Lithium and imipramin effects on paw preference in cats.
The effect of lithium and imipramin on paw preference was studied in cats. Paw preference was assessed by the food-reaching test. It was found that lithium decreased, and imipramin increased the asymmetry of paw use. The lithium effect was antagonized by imipramin. It was concluded that paw preference may reflect a biochemical asymmetry in the brain. These effects of these psychoactive drugs may be of importance for the origin and treatment of affective disorders.
Tan
U
U
Atatürk University, Medical Faculty, Institute of Physiology, Erzurum, Turkey.
Kara
I
I
Tan
S
S
D000818:Animals; D002415:Cats; D005552:Forelimb; D007839:Functional Laterality / Q000187:drug effects*; D007099:Imipramine / Q000494:pharmacology*; D008094:Lithium / Q000037:antagonists & inhibitors / Q000494:pharmacology*
D008094:Lithium; D007099:Imipramine