The effect of chlorpheniramine on asthma.
Patients with stable asthma can tolerate antihistamines without any significant deleterious effects both on a short- and a long-term basis. In addition, patients with steroid-dependent asthma appear to tolerate antihistamines without any significant deleterious effects. Therefore, oral chlorpheniramine does not appear to have ill effects on patients with asthma. Warning labels required by the FDA for antihistamine use in asthmatics are unnecessary.
Ricci
A R
AR
Brown University Program in Medicine, Division of Allergy, Rhode Island Hospital, Providence 02903.
Settipane
R J
RJ
Goldstein
B M
BM
Kalliel
J N
JN
Settipane
G A
GA
D000328:Adult; D001249:Asthma / Q000188:drug therapy* / Q000503:physiopathology; D002744:Chlorpheniramine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D005541:Forced Expiratory Volume / Q000187:drug effects; D006801:Humans; D008297:Male; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy / Q000503:physiopathology; D013256:Steroids / Q000008:administration & dosage / Q000627:therapeutic use; D013997:Time Factors; D014797:Vital Capacity / Q000187:drug effects
D013256:Steroids; D002744:Chlorpheniramine