Riboflavin intakes and status of morbidly obese females during the first postoperative year following gastroplasty.
Eighteen women participated in a prospective study to assess the need for supplemental riboflavin after gastroplasty. Three groups of five patients received either a placebo or 0.6 or 1.2 mg riboflavin daily for up to 12 months, except during months 4 and 7 when all participants were given a "one-a-day" supplement containing 1.7 mg riboflavin. Dietary intakes of riboflavin decreased from 1.43 +/- 0.17 mg before the operation to 0.70 +/- 0.07 mg at 3 months, and then increased to 1.02 +/- 0.17 mg by 6 months. Even at 12 months, only 33% of the subjects had dietary intakes greater than or equal to 1.2 mg. All those with total intakes less than or equal to 1.7 mg at 3 months had impaired riboflavin status, as indicated by an erythrocyte gluthatione reductase activity coefficient greater than 1.40 and an erythrocyte riboflavin concentration less than 372 nmol/L. In contrast, 62% of the same subjects had urinary riboflavin excretion in the acceptable range. Supplemental intake of 1.7 mg riboflavin appeared to prevent tissue depletion in all subjects.
Turkki
P R
PR
Department of Nutrition and Food Management, Syracuse University, New York 13244-1250.
Ingerman
L
L
Schroeder
L A
LA
Chung
R S
RS
Chen
M
M
Russo-McGraw
M A
MA
Dearlove
J
J
D000328:Adult; D004044:Dietary Proteins / Q000008:administration & dosage; D004311:Double-Blind Method; D002149:Energy Intake; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D015391:Gastroplasty; D005980:Glutathione Reductase / Q000097:blood; D006801:Humans; D008875:Middle Aged; D009767:Obesity, Morbid / Q000378:metabolism / Q000601:surgery*; D011184:Postoperative Period; D011446:Prospective Studies; D012044:Regression Analysis; D012256:Riboflavin / Q000008:administration & dosage* / Q000097:blood / Q000652:urine; D015431:Weight Loss
D004044:Dietary Proteins; D005980:Glutathione Reductase; D012256:Riboflavin