title: Bone flap replacement vs acrylic cranioplasty: a clinical audit.
abstract: A 5-year retrospective study comparing bone flap replacement with acrylic cranioplasty was carried out. There was no significant difference in the high infection rates associated with the two procedures. We suggest that antibiotic-impregnated acrylic cranioplasty may be the safest and best surgical procedure based on the orthopaedic experience with gentamicin-impregnated cement in joint replacement surgery.
authors: Department of Neurosurgery, University Hospital of Wales, Heath Park, Cardiff, UK.
authors: T Z
authors: TZ
authors: Aziz
authors: B G
authors: BG
authors: Mathew
authors: P J
authors: PJ
authors: Kirkpatrick
mesh_terms: D000180:Acrylic Resins; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008485:Medical Audit; D011292:Premedication; D012189:Retrospective Studies; D013518:Surgery, Plastic / Q000009:adverse effects / Q000379:methods*; D013524:Surgical Flaps / Q000009:adverse effects / Q000379:methods*; D013530:Surgical Wound Infection / Q000453:epidemiology / Q000209:etiology; D006113:United Kingdom / Q000453:epidemiology
chemical_list: D000180:Acrylic Resins; D000900:Anti-Bacterial Agents