title: Gene mapping of mouse laminin A and B2 subunits using mouse-Chinese hamster somatic cell hybrids.
abstract: Laminin is a multichain extracellular matrix glycoprotein found primarily in basement membranes. The molecule is made up of three subunits, designated as A, B1, and B2. Using an 850-base cDNA probe for the mouse laminin A-chain and a 1000-base cDNA probe for the mouse laminin B2 chain, we have screened mouse-Chinese hamster somatic cell hybrids in order to assign the genes for each of these polypeptides to their respective mouse chromosome. We have determined that the mouse laminin B2-chain gene is located on chromosome 1 (confirming this assignment) and the laminin A-chain gene is located on chromosome 17.
authors: Department of Anatomy, Cell Biology and Neurobiology, Albany Medical College, New York.
authors: N W
authors: NW
authors: Kaye
authors: A E
authors: AE
authors: Chung
authors: P A
authors: PA
authors: Lalley
authors: M E
authors: ME
authors: Durkin
authors: S L
authors: SL
authors: Phillips
authors: R L
authors: RL
authors: Church
mesh_terms: D000818:Animals; D015139:Blotting, Southern; D006822:Hybrid Cells; D007797:Laminin / Q000235:genetics*; D051379:Mice
chemical_list: D007797:Laminin