[Effect of castration on bone mineral metabolism in rats].
We have tried to experimentally determine what effect castration is going to have on rats bone and on the main mineral bone regulatory hormones. Twenty ovariectomized female rats and their age and weight matched controls were used. Parathormone, calcitonin, osteocalcin and serum calcium levels were determined as well as mineral bone content and head of femur density. Castration produces, in rat, a marked decrease in circulating calcitonin, parathormone (PTH) and bone density, with no changes in mineral bone concentration. Finally, castration produces a slight increase in osteocalcin serum levels although without a statistical value.
González Rodríguez
M D
MD
Universidad de Las Palmas de Gran Canaria, Colegio Universitario de Las Palmas.
Sosa Henríquez
M
M
Limiñana Cañal
J M
JM
Betancor León
P
P
D000818:Animals; D015519:Bone Density; D001842:Bone and Bones / Q000378:metabolism*; D005260:Female; D008903:Minerals / Q000378:metabolism*; D010052:Ovariectomy; D010053:Ovary / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains
D008903:Minerals
Efecto de la castración sobre el metabolismo mineral óseo en la rata.