title: Clinical use of the Berlin Biventricular Assist Device as a bridge to transplantation.
abstract: The Berlin Artificial Heart System/Biventricular Assist Device (BVAD) was used in 38 patients. 1) Twenty-eight patients were awaiting cardiac transplantation (Tx) (age 23-56 yrs). All patients had contraindications not allowing immediate Tx. 2) Five patients were emergency cases not on our Tx list (postcardiotomy cardiac failure, acute myocarditis) (age 28-59). 3) Five patients were post Tx patients with graft failure (age 22-52). Extracorporal circulation was used for implantation of the BVAD. In group 1, 21 of 28 patients (pts) recovered, and all were subsequently transplanted after 6 hours to 39 days, when all organ function was restored. In 7 pts, mechanical circulation was terminated after 1-40 days because of further deterioration. Five of the transplanted pts died, 14 pts survived (greater than 30 days), and 2 pts were just transplanted with satisfactory postoperative courses. Of group 2 and 3 pts, two were successfully weaned. In one patient the allograft recovered after 11 days of support.
authors: Deutsches Herzzentrum Berlin, Herz-, Thorax- und Gefässchirurgie, West Germany.
authors: A
authors: A
authors: Schiessler
authors: H
authors: H
authors: Warnecke
authors: N
authors: N
authors: Friedel
authors: E
authors: E
authors: Hennig
authors: R
authors: R
authors: Hetzer
mesh_terms: D002302:Cardiac Output / Q000502:physiology; D004867:Equipment Design; D005500:Follow-Up Studies; D006333:Heart Failure / Q000401:mortality / Q000503:physiopathology*; D016027:Heart Transplantation / Q000502:physiology*; D006354:Heart, Artificial; D006353:Heart-Assist Devices; D006801:Humans; D012307:Risk Factors; D015996:Survival Rate; D016276:Ventricular Function / Q000502:physiology*