[Early results of the treatment of patients with recurrences of pulmonary tuberculosis].
Efficacy of treatment of 106 patients with destructive forms of recurring pulmonary tuberculosis is analysed. Treatment was conducted in comparable groups on 2 chemotherapeutic regimens. With regimen 1 consisting of a 4-drug combination, cavity closure was evident in 72.2%, while with regimen 2 including 3 drugs, cavities were closed in 42.3% of the cases. Cavity decay healing and bacteriostasis rates were higher for regimen 1 as compared to regimen 2, though the incidence of bacteriostasis was the same with both chemotherapeutic regimens, i.e. in 93.6% and in 92.8% with regimen 1 and 2, respectively. The incidence of side effects was practically unchanged in terms of the given chemotherapeutic regimen. A 4-drug combination should be chosen for the management of patients with destructive recurring pulmonary tuberculosis.
Bobarykin
V S
VS
D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D013997:Time Factors; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
D000995:Antitubercular Agents
Neposredstvennye resul'taty lecheniia bol'nykh s retsidivom tuberkuleza legkikh.