title: [Histiocytosis X--histiocytosis from Langerhans' cells].
abstract: A review of literature has been presented involving clinicomorphological characteristics of certain variants of histiocytosis X (HX) and current conception considering this disease as an immunopathologic process that is underlain by reactive proliferation of a specific subtype of antigen-presenting macrophages--Langerhans' cells. Clinico-morphological picture has been described and the results of successful treatment with roferon (human gene-engineering alpha 2-interferon) in 3 adult patients with HX have been presented. It is stressed that the actual effectiveness of the treatment with roferon could not be critically evaluated due to a high frequency of spontaneous remissions of this disease.
authors: E A
authors: EA
authors: Lukina
authors: A S
authors: AS
authors: Kozlovskaia
authors: I B
authors: IB
authors: Kaplanskaia
authors: R A
authors: RA
authors: Mokeeva
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000473:pathology*; D006801:Humans
vernacular_title: Gistiotsitoz Kh--gistiotsitoz iz kletok langergansa.