Applications of bit-mapped "cognitive" potentials (ERPs) in clinical neurophysiology--CNV complex in patients with destruction of the dorso-anteromedial bidirectional thalamo-prefrontal pathways.
We discuss the most important current problems relative to the recording procedures and methods of analysis, using inter alia spatio/temporal topographic maps, of some cognitive event-related potentials (CNV complex etc.) in normal and pathological conditions. After these initial premises of neurocognitive electrophysiology, we summarize the results for 8 patients in whom we examined the effects on CNV activity formation of surgical or spontaneous bihemispheric deafferentation of prefrontal/premotor cortical associative areas. These observations bear out the hypothesis that the bidirectional homohemispheric long and short distance pathways connecting associative parieto-temporal and occipital cortical areas to the prefrontal ones, play an important role in the genesis of the long-latency cognitive event-related potentials.
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Dipartimento di Scienze Neurologiche e Psichiatriche, Università di Firenze.
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D000328:Adult; D001927:Brain Diseases / Q000503:physiopathology; D003071:Cognition / Q000502:physiology*; D005071:Evoked Potentials; D005625:Frontal Lobe / Q000503:physiopathology; D006801:Humans; D008297:Male; D009434:Neural Pathways / Q000503:physiopathology; D009482:Neurophysiology / Q000379:methods*; D013788:Thalamus / Q000503:physiopathology