title: Development of a multiple thin-film semimicro DC-probe for intracerebral recordings.
abstract: A thin-film multiple-electrode probe for measuring de potentials at eight sites with interdistances of 1 mm was constructed for the investigation of slow potential changes in deep regions of the human brain during surgery. The thin-film electrodes had to be placed on curved cylinder-shaped surgical instruments with dimensions of 2 mm diameter and 33 cm length used with the Freiburg stereotactic equipment. Several novel technological steps had to be introduced for the solution of the encountered problems: 1) Structuring of the metal layers on curved substrates was accomplished by using flexible masks. 2) Special feed-through technologies had to be invented in order to obtain reliable connections between the thin-film sensors and the copper wires inside the stereotactic instrument. 3) Thin-film Ag-AgCl electrodes had to be formed in order to obtain satisfying recordings of slow potential changes below 10 Hz. Slow potential changes were recorded from different depths in interdistances of only 1 mm with these new miniaturized thin film Ag-AgCl electrodes and bipolar recordings with an electrode interdistance of only 3 mm showed clearly the appearance of Bereitschaftspotentials.
authors: Institut für allgemeine Elektrotechnik und Elektronik, Technical University of Vienna, Austria.
authors: G A
authors: GA
authors: Urban
authors: J A
authors: JA
authors: Ganglberger
authors: F
authors: F
authors: Olcaytug
authors: F
authors: F
authors: Kohl
authors: R
authors: R
authors: Schallauer
authors: M
authors: M
authors: Trimmel
authors: H
authors: H
authors: Schmid
authors: O
authors: O
authors: Prohaska
mesh_terms: D001931:Brain Mapping / Q000295:instrumentation*; D004553:Electric Conductivity; D004566:Electrodes; D004569:Electroencephalography; D004867:Equipment Design; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000503:physiopathology; D013238:Stereotaxic Techniques; D013788:Thalamus / Q000503:physiopathology*