Aromatic DNA adducts in white blood cells of coke workers.
White blood cell DNA adducts were measured in coke workers, local controls and countryside controls using the 32P-postlabelling technique. The method detected aromatic adducts including those formed by polycyclic aromatic hydrocarbons (PAHs). Coke workers are heavily exposed to PAHs particularly when working at the batteries. A difference in adduct levels was noted between the coke workers at the battery as compared to other jobs. The adduct levels in the non-battery were higher than those in the countryside controls.
Hemminki
K
K
Institute of Occupational Health, Helsinki, Finland.
Grzybowska
E
E
Chorazy
M
M
Twardowska-Saucha
K
K
Sroczynski
J W
JW
Putman
K L
KL
Randerath
K
K
Phillips
D H
DH
Hewer
A
A
D000395:Air Pollutants, Occupational / Q000032:analysis; D001345:Autoradiography; D001564:Benzo(a)pyrene / Q000032:analysis*; D002274:Carcinogens, Environmental / Q000097:blood*; D002855:Chromatography, Thin Layer; D003077:Coke / Q000009:adverse effects*; D004247:DNA / Q000097:blood*; D018736:DNA Adducts; D004784:Environmental Monitoring; D006801:Humans; D007962:Leukocytes / Q000737:chemistry*; D008669:Metallurgy
D000395:Air Pollutants, Occupational; D002274:Carcinogens, Environmental; D003077:Coke; D018736:DNA Adducts; C056612:benzo(a)pyrene-DNA adduct; D001564:Benzo(a)pyrene; D004247:DNA