title: In vitro antigen-binding properties of coelomocytes of Eisenia foetida (Annelida).
abstract: Annelids are capable of cellular and humoral defence reactions against foreign antigens. The main aim of this study was to characterise the antigen-binding properties of coelomocytes of Eisenia foetida by means of quantitative autoradiography and direct measurement of radioactivity. It was found that the antigen-binding capacity was significantly increased after antigen stimulation. Furthermore, the preincubation of coelomocytes with non-labelled proteins reduced the binding of radiolabelled antigen. The highest level of inhibition was found when the same protein was used for preincubation. These results indicate that antigen-binding properties are to some extent specific.
authors: Department of Immunology, Czechoslovak Academy of Science, Prague.
authors: M
authors: M
authors: Bilej
authors: L
authors: L
authors: Tuckova
authors: J
authors: J
authors: Rejnek
authors: V
authors: V
authors: Vetvicka
mesh_terms: D000818:Animals; D000845:Annelida / Q000166:cytology / Q000276:immunology*; D000941:Antigens / Q000276:immunology*; D000954:Antigens, Surface / Q000276:immunology; D001147:Arsanilic Acid / Q000276:immunology; D001345:Autoradiography; D066298:In Vitro Techniques; D007700:Kinetics; D012709:Serum Albumin / Q000276:immunology*
chemical_list: D000941:Antigens; D000954:Antigens, Surface; D012709:Serum Albumin; D001147:Arsanilic Acid