Relationship between asthma and seasonal allergic rhinitis in schoolchildren.
The relationship between sensitization to common allergens and the development of asthma and seasonal allergic rhinitis (SAR) was investigated in a total of 419 schoolchildren in a farming community where allergens of both Dermatophagoides farinae (Df) and orchard grass (OG) pollen predominate. Twelve subjects (2.9%) were found to have asthma and 35 subjects (8.4%) SAR. There was no significant association between occurrences of asthma and SAR. The incidence of asthma correlated with DF-specific IgE levels but not with OG-specific IgE levels, whereas that of SAR correlated with OG-specific IgE levels but not with Df-specific IgE levels. No significant correlation was detected between IgE antibody levels against Df and OG. These results suggest that asthma occurs independently of SAR.
Shibasaki
M
M
Department of Pediatrics, University of Tsukuba, Japan.
Hori
T
T
Shimizu
T
T
Isoyama
S
S
Takeda
K
K
Takita
H
H
D000293:Adolescent; D000485:Allergens / Q000276:immunology / Q000494:pharmacology; D000818:Animals; D000941:Antigens / Q000276:immunology; D001249:Asthma / Q000453:epidemiology* / Q000276:immunology; D002648:Child; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis / Q000276:immunology; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008297:Male; D008925:Mites / Q000276:immunology; D006109:Poaceae; D011058:Pollen / Q000276:immunology; D011852:Radioallergosorbent Test; D006255:Rhinitis, Allergic, Seasonal / Q000453:epidemiology* / Q000276:immunology
D000485:Allergens; D000941:Antigens; D007073:Immunoglobulin E