Alopecia with rickets: an end organ unresponsiveness to 1,25-dihydroxyvitamin D--a case report.
Two siblings of a rare syndrome of vitamin D dependent type II rickets are reported for the first time from India. The clinical and biochemical picture was characterised by florid rickets, alopecia, hypocalcemia and resistance to therapy with high dosages of vitamin D3. Due to lack of facilities for estimation of 1,25(OH)2D, alopecia remains the only clue to the diagnosis of this rare syndrome in association with resistant rickets.
Gupta
P C
PC
Dept. of Pediatrics, Lady Hardinge Medical College, New Delhi.
Patwari
A K
AK
Mullick
D N
DN
D000505:Alopecia; D002117:Calcitriol / Q000627:therapeutic use*; D002675:Child, Preschool; D004100:Dihydroxycholecalciferols / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D012279:Rickets / Q000097:blood / Q000150:complications / Q000188:drug therapy*
D004100:Dihydroxycholecalciferols; D002117:Calcitriol