A tether-free, moving actuator total artificial heart.
An electromechanical moving-actuator TAH was developed and implanted for 5 days in a calf experiment. The efficiency and durability were further improved using pendulous motion of the actuator. This new pendulum pump has a circular motion produced by gear mechanisms connected to the motor. It has a height (from valves to housing bottom) of 7 cm and centrally directed inlets and outlets for good fittability. Active filling (-10 mmHg) inside inner blood sacs was produced by the suction effects of the outer sacs attached to a moving actuator. Two acute animal experiments were performed using the pendulum pump with a Coridale sheep (50 kg weight), and a male calf (70 kg weight). A test was made of 30 minutes of tether-free operation of the implanted pendulum pump inside the small chest of the calf. The pump shows the engineering feasibility of the implantable electrical TAH inside a human chest cavity.
Min
B G
BG
Department of Biomedical Engineering, College of Medicine, Seoul National University, Korea.
Kim
H C
HC
Lee
S H
SH
Chang
J K
JK
Choi
J W
JW
Kim
J W
JW
Seo
K P
KP
Rho
J R
JR
Ahn
H
H
Kim
S W
SW
D000818:Animals; D001794:Blood Pressure / Q000502:physiology; D002417:Cattle; D004867:Equipment Design; D006354:Heart, Artificial; D006439:Hemodynamics / Q000502:physiology*; D008297:Male; D008955:Models, Cardiovascular