[Congenital adrenal hyperplasia secondary to 21-hydroxylase deficiency].
The clinical charts belonging to patients suffering from congenital adrenal hyperplasia secondary to a deficiency of the enzyme 21-hydroxylase seen at the Endocrinology Department during 1978 to 1988 were reviewed. The 34 patients were analyzed for various clinical and biochemical parameters when admitted and during their follow-up. The reason for their consultation, in 73.5% of the cases was due to the presence of ambiguity in their genitalia at the time of their birth. The most frequent clinical variety was the classical or "salt-loser" in 55.8% of the cases. The growth chart analysis showed that those patients who were "salt-losers" grew and were categorized in lesser percentiles than those who had the simple variety of the disease. The results are similar to those reported in worldwide literature. A close follow-up with emphasis placed on clinical and laboratory data seems to allow for adequate growth and development of these patients.
Rodríguez-León
G A
GA
Departamento de Endocrinología, Hospital Infantil de México Federico Gómez, México, D.F.
Bautista-Rojas
J J
JJ
Dorantes-Alvarez
L M
LM
D000312:Adrenal Hyperplasia, Congenital / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male
Hiperplasia adrenal congénita secundaria a deficiencia de 21-hidroxilasa.