[Experimental research on toxic reaction of rats to sodium fluoride after a short period of exposure].
This article reported the effects of 3 different dosages of NaF on the rats when they were exposed for 30-90 days. The results showed that many toxic indexes had significant changes when high dose of NaF (3.37 mg/kg) was given to rats for 30 days. Some toxic indexes had significant changes when medium dose of NaF (1.12 mg/kg) was given to rats for 90 days. But no significant difference was observed when compared to the normal control group, when low dose of NaF (0.37 mg/kg) was given to rats for 90 days.
Zhang
J
J
Department of Military Hygiene, 4th Military Medical University, Xi'an.
D000818:Animals; D001806:Blood Urea Nitrogen; D004305:Dose-Response Relationship, Drug; D005260:Female; D009050:Fluorosis, Dental; D007668:Kidney / Q000033:anatomy & histology; D008297:Male; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D012969:Sodium Fluoride / Q000633:toxicity*
D012969:Sodium Fluoride