Computer pattern recognition: an automated method for evaluating motor activity and testing for neurotoxicity.
An economical computer-based pattern recognition system, which has been designed to observe, classify, analyze, and record the spontaneous motor activity of the laboratory rat, is presented. The advantages and disadvantages of the system are assessed in terms of characteristics generally held to be desirable for a motor activity screen of potentially neurotoxic chemicals. Data from rats exposed to 1 mg/kg d-amphetamine are compared with similar data previously taken with an earlier version of the system at another laboratory.
Hopper
D L
DL
Veterinary Diagnostic Laboratory, Iowa State University, Ames 50011.
Kernan
W J
WJ
Wright
J R
JR
D000818:Animals; D002965:Classification; D003627:Data Interpretation, Statistical; D007091:Image Processing, Computer-Assisted; D008838:Microcomputers; D009043:Motor Activity / Q000187:drug effects*; D009420:Nervous System / Q000187:drug effects*; D010363:Pattern Recognition, Automated; D051381:Rats; D015203:Reproducibility of Results; D014116:Toxicology / Q000379:methods*; D014741:Video Recording