Pefloxacin in the treatment of septicaemia: three years' experience.
Sixty cases of septicaemia treated with pefloxacin, alone (30) or in combination with other antibiotics (30) were analysed retrospectively. A satisfactory outcome was achieved in 33 (87%) of 38 evaluable Gram-negative septicaemias (including success in 25 of 29 treated with pefloxacin alone) and in 15 of 21 staphylococcal septicaemias, mainly treated with combinations of antibiotics. Failures and relapses were associated with a variety of local or systemic underlying conditions.
Bernard
E
E
Maladies Infectieuses et Tropicales, CHRU Nice, Hôpital de l'Archet, France.
Durant
J
J
Elbaze
P
P
Dellamonica
P
P
D000284:Administration, Oral; D000328:Adult; D000900:Anti-Bacterial Agents; D004359:Drug Therapy, Combination / Q000008:administration & dosage / Q000627:therapeutic use; D004927:Escherichia coli Infections / Q000188:drug therapy; D005260:Female; D006801:Humans; D007710:Klebsiella Infections / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D015366:Pefloxacin / Q000008:administration & dosage / Q000627:therapeutic use*; D011512:Proteus Infections / Q000188:drug therapy; D012189:Retrospective Studies; D018805:Sepsis / Q000188:drug therapy*; D013997:Time Factors
D000900:Anti-Bacterial Agents; D015366:Pefloxacin