[The use of apressin in patients with pulmonary tuberculosis and functional disorders of the external respiration and hemodynamics].
Effects of apressin, a peripheral vasodilator, on external respiration function and central hemodynamics was studied in 51 patients with pulmonary tuberculosis. The study showed that a single administration of 20 mg apressin in pulmonary tuberculosis patients failed to bring about any changes in both external respiration function and blood gases, only causing a minor shift in the buffer bases. Systolic pressure in the pulmonary artery remained unchanged after a single 20 mg dose of apressin was given. A statistically significant decrease in total pulmonary vascular resistance and an increase of the central hemodynamic values in pulmonary tuberculosis patients with hypokinetic type of circulation are recorded.
Mar'iandyshev
A O
AO
Tikhonov
V A
VA
Evsraf'ev
Iu A
IuA
Grigor'ev
Iu G
IuG
D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D006830:Hydralazine / Q000627:therapeutic use*; D012119:Respiration / Q000187:drug effects*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy* / Q000503:physiopathology; D014665:Vasodilator Agents / Q000627:therapeutic use*
D014665:Vasodilator Agents; D006830:Hydralazine
Ispol'zovanie apressina u bol'nykh tuberkulezom legkikh s narusheniem funktsii vneshnego dykhaniia i gemodinamiki.