[Experimental investigations of the propagation mechanism and the nerve regulatory mechanism of the interdigestive migrating electric complex in intestinal movement].
Segments and Thirty-Vella type loops of the small intestine of dogs were prepared, and the excitation propagation pattern of the interdigestive migrating electric complex (IMEC) was observed by electromyography. The nerve regulatory mechanism in intestinal movement was investigated. The results indicated that first, the frequency of the basic electric rhythm (BER) is controlled so that a downward gradient is formed from the upper to the lower intestine, but this gradient continues to be controlled by a two-dimensional control mechanism involving parietal factors and extrinsic nerves due to transection of the intestines and damage to the extrinsic nerves in the dominant region. However, propagation of the IMEC in the small intestine appeared to be regulated by a combination of the two-dimensional control mechanism involving extrinsic and parietal nerves corresponding to the BER control mechanism. It was clear that the propagation mechanism of IMEC is related to the BER frequency, and propagation of the IMEC is downward in accordance with the frequency gradient of BER.
Ozawa
T
T
2nd Department of Surgery, Toho University, School of Medicine, Tokyo.
Kawamura
K
K
Kitahara
S
S
Murakuni
H
H
Deguchi
H
H
Shimada
N
N
Tsugu
Y
Y
D000818:Animals; D003714:Denervation; D004285:Dogs; D004435:Eating; D004576:Electromyography; D005769:Gastrointestinal Motility / Q000502:physiology*; D066298:In Vitro Techniques; D007421:Intestine, Small / Q000294:innervation / Q000502:physiology*; D008026:Ligation; D010525:Peripheral Nerves / Q000502:physiology*