[The Hellp syndrome: is this a clinical form of thrombotic microangiopathy?].
There are similarities between the clinical, biological and histological features of thrombotic micro-angiopathy (TMA) when it is a complication of pregnancy and the "Help Syndrome" (HS). HS can be associated in pregnancy with pre-eclampsia, thrombocytopenia, micro-angiopathic haemolysis and hepatic cytolysis. We have analysed on the one hand biological features of six cases that occurred in the literature and two personal cases of thrombotic micro-angiopathy that had been proven histologically; and on the other hand the histological findings of the liver in two cases of the literature and in a personal case of HS. Demonstration that in HS deposits exist under the endothelium in the region of the hepatic biopsy suggest that the latter can only be a special clinical form of TMA.
Ducroz
B
B
Polyclinique St-François, St-Antoine, Montluçon.
Villemonteix
P
P
Magnin
G
G
Pourrat
O
O
D000743:Anemia, Hemolytic / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D011225:Pre-Eclampsia / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D013577:Syndrome; D013921:Thrombocytopenia / Q000097:blood / Q000175:diagnosis* / Q000473:pathology
Le Hellp syndrome: forme clinique de la micro-angiopathie thrombotique?