Increased placental phospholipase A2 activities in pre-eclampsia.
Phospholipase A2 activity was significantly increased in placental homogenates from 22 patients with pre-eclampsia in comparison to placental homogenates from women with uncomplicated pregnancy. Such an abnormality may be responsible for an altered release of free arachidonic acid, thus playing a major role in the pathogenesis of this syndrome.
Jendryczko
A
A
Department of Biochemistry and Chemistry, Silesian Medical School, Katowica.
Drózdz
M
M
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D010741:Phospholipases A / Q000378:metabolism*; D054467:Phospholipases A2; D010920:Placenta / Q000201:enzymology*; D011225:Pre-Eclampsia / Q000175:diagnosis / Q000201:enzymology*; D011247:Pregnancy
D010741:Phospholipases A; D054467:Phospholipases A2