title: Fine needle aspiration biopsy of cystic benign lymphoepithelial lesion of the parotid gland in patients at risk for the acquired immune deficiency syndrome.
abstract: Cystic benign lymphoepithelial lesion (BLL), a previously rare lesion of the parotid gland consisting of marked lymphoid hyperplasia with accompanying squamous-lined cysts, has recently been described in patients with the acquired immune deficiency syndrome (AIDS) or AIDS risk factors. Thirteen fine needle aspiration (FNA) samples of parotid gland masses from patients with AIDS (one case), AIDS risk factors (five cases) or denial of AIDS risk factors (two cases) and a histopathologic diagnosis of BLL were examined. The FNA features that correlated best with the histopathologic findings were (1) a heterogeneous lymphoid population, (2) scattered single and/or clustered foamy macrophages and (3) superficial and/or anucleated squamous cells. Most aspirates showed some combination of these three components. The differential diagnostic considerations, the clinical and radiologic correlations and the relationship of this lesion to HIV infection are discussed. Patients with parotid masses whose aspirates consist of some combination of squamous cells, lymphocytes and foamy macrophages should be questioned for possible AIDS risk factors.
authors: Department of Pathology, New York University Medical Center, New York 10016.
authors: M D
authors: MD
authors: Finfer
authors: L
authors: L
authors: Gallo
authors: A
authors: A
authors: Perchick
authors: R A
authors: RA
authors: Schinella
authors: D E
authors: DE
authors: Burstein
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000473:pathology; D000328:Adult; D001707:Biopsy, Needle / Q000379:methods; D003560:Cysts / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D006716:Homosexuality; D006801:Humans; D006965:Hyperplasia; D008198:Lymph Nodes / Q000473:pathology; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010305:Parotid Diseases / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D010306:Parotid Gland / Q000473:pathology*; D012307:Risk Factors; D019966:Substance-Related Disorders