[Long-term consequences of the damaging effect of cytostatic drugs on hematopoiesis and lymphoid tissue].
The evidence on the changes detectable in remote periods (at 1, 3, and 6 months) is presented. It shows that the quantitative and functional defects are retained in the hemopoietic and lymphoid tissues within 3-6 months after exposure to the effects of various cytostatic agents. These defects may be corrected by means of immunomodulators.
Gol'dberg
E D
ED
Novitskiĭ
V V
VV
Zapuskalova
O B
OB
Klimova
M Iu
MIu
D000276:Adjuvants, Immunologic / Q000494:pharmacology; D000818:Animals; D000970:Antineoplastic Agents / Q000009:adverse effects*; D001792:Blood Platelets / Q000187:drug effects; D001853:Bone Marrow / Q000187:drug effects; D002478:Cells, Cultured; D003520:Cyclophosphamide / Q000009:adverse effects; D004317:Doxorubicin / Q000009:adverse effects; D006410:Hematopoiesis / Q000187:drug effects*; D008221:Lymphoid Tissue / Q000187:drug effects*; D051379:Mice; D008808:Mice, Inbred CBA; D051381:Rats; D013154:Spleen / Q000187:drug effects; D013997:Time Factors; D014747:Vinblastine / Q000009:adverse effects
D000276:Adjuvants, Immunologic; D000970:Antineoplastic Agents; D014747:Vinblastine; D004317:Doxorubicin; D003520:Cyclophosphamide
Problemy otdalennykh posledstviĭ povrezhdaiushchego deĭstviia tsitostaticheskikh preparatov na krovetvorenie i limfoidnuiu tkan'.