title: Finding hydrophobic microdomains using an object-oriented database.
abstract: A procedure for finding clusters of adjacent residues in protein hydrophobic cores--hydrophobic microdomains--has been proposed by Plochocka et al. A program is presented that finds hydrophobic microdomains, making use of protein structure data stored in an object-oriented database and the list-processing features of Prolog. Alternative definitions for hydrophobic microdomains are explored. Results are presented for haemoglobin.
authors: Department of Computing Science, University of Aberdeen, King's College, UK.
authors: G J
authors: GJ
authors: Kemp
authors: P M
authors: PM
authors: Gray
mesh_terms: D000465:Algorithms; D006454:Hemoglobins / Q000737:chemistry; D046911:Macromolecular Substances; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*; D012984:Software; D012985:Software Design
chemical_list: D006454:Hemoglobins; D046911:Macromolecular Substances; D011506:Proteins