Structure of a mouse histone-encoding gene cluster.
In addition to a previously described histone (H)-encoding H4 gene [Meier et al., Nucleic Acids Res. 17 (1989) 795], the mouse genomic DNA clone 53 contains two H3 genes, one functional and one partially deleted H2A gene, and one H2B gene. Clone 53 overlaps for 3 kb with MH143, another previously isolated mouse H-encoding clone [Yang et al., J. Biol. Chem. 262 (1987) 17118-17125], thus defining a 32-kb region of mouse chromosome 13 with a total of seven H-encoding genes. We have determined the nucleotide sequences and transcription start points of two genes coding for the H2A.1 and H3.2 proteins.
Gruber
A
A
Abteilung für Entwicklungsbiologie, Zoologisches Institut der Universität Bern, Switzerland.
Streit
A
A
Reist
M
M
Benninger
P
P
Böhni
R
R
Schümperli
D
D
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D006657:Histones / Q000235:genetics*; D051379:Mice; D008969:Molecular Sequence Data; D005810:Multigene Family; D015183:Restriction Mapping; D014158:Transcription, Genetic
D006657:Histones