Familial aggregation of defects of the left-sided structures of the heart.
A family is described where a mother and her three children had left heart defects. Three members of a second family were also noted to have such defects. This experience adds support to the hypothesis that in some families, such defects may have an incidence of recurrence higher than the 3% predicted by a multifactorial model.
Menahem
S
S
Department of Paediatrics and Cardiology, Monash Medical Centre, Melbourne, Australia.
D000328:Adult; D001017:Aortic Coarctation / Q000235:genetics; D001024:Aortic Valve Stenosis / Q000151:congenital* / Q000235:genetics; D005260:Female; D006330:Heart Defects, Congenital / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D008297:Male