Physical activity and colon cancer: a case-referent study in Stockholm.
A population-based case-referent study on physical activity (during working and recreational hours) and colon cancer was performed in Stockholm in 1986-1988. The study included 1,081 subjects. Low physical activity was associated with an excess risk of colon (but not rectum) cancer for both men and women, showing a dose-response relationship with decreasing levels of physical activity. The effect was seen in the left colon (relative risk = 3.2, 95% confidence interval = 1.5-7.0) rather than in the right colon (relative risk = 1.1, 0.5-2.5). These results persisted after adjustment for year of birth, gender, body mass, intake of total energy, protein, total fat, dietary fibre, and browned meat surface.
Gerhardsson de Verdier
M
M
Department of Epidemiology, Karolinska Institutet, Stockholm, Sweden.
Steineck
G
G
Hagman
U
U
Rieger
A
A
Norell
S E
SE
D000230:Adenocarcinoma / Q000453:epidemiology*; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D003110:Colonic Neoplasms / Q000453:epidemiology*; D015444:Exercise; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000453:epidemiology*; D012306:Risk; D012307:Risk Factors; D013548:Sweden / Q000453:epidemiology