Influence of time of mating and paced copulation on induction of pseudopregnancy in cyclic female rats.
The present experiment was designed to examine whether changes occur during the course of behavioural oestrus in the sensitivity of the female to copulatory stimulation and in patterns of sexual behaviour which might influence the likelihood of luteal maintenance. Cyclic female rats were mated on the evening of pro-oestrus (21:00 h) or early on the morning of oestrus (05:00 h) and received either 5 or 10 intromissions from males under conditions which allowed or did not allow pacing of contacts with males to occur. During mating, the levels of sexual receptivity, the timing of sexual mounts from males, and pacing behaviours were measured. The occurrence of pseudopregnancy or pregnancy in each animal was determined by examining vaginal smears for 14 days after mating and by examining the uterus for the presence of fetuses at the end of the experiment. At both mating times, pacing of copulation with males increased the likelihood of prolonged luteal activity. However, females were more likely to become pseudopregnant following non-paced mating at 05:00 h than at 21:00 h the previous evening. Of those females receiving an ejaculation during mating, no difference were seen between groups in the incidence of pregnancy. This change in sensitivity to cervical-vaginal stimulation during oestrus was not associated with changes in sexual receptivity or pacing behaviour. The ability of cervical-vaginal stimulation to induce pseudopregnancy therefore increases toward the end of the period of oestrus, but the behavioural mechanisms which regulate receipt of such stimulation remain constant during that time.
Frye
C A
CA
Department of Biology, Boston University, Massachusetts 02193.
Erskine
M S
MS
D000818:Animals; D002584:Cervix Uteri / Q000502:physiology; D003307:Copulation / Q000502:physiology*; D003340:Corpus Luteum Maintenance / Q000502:physiology; D004971:Estrus / Q000502:physiology*; D005260:Female; D011247:Pregnancy; D011555:Pseudopregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors; D014621:Vagina / Q000502:physiology