[A case of hemoptysis due to administration of an anti-thrombotic drug].
A 63-year-old woman was referred to our division because of massive hemoptysis (200 ml) after administration of ticlopidine, an anti-thrombotic drug, for prevention of recurrent brain infarction. Ticlopidine treatment was stopped on the first hospital day, thereafter the patient's hemoptysis immediately disappeared. A chest roentgenogram and broncho-fiberscopic examination did not reveal any organic lesion associated with hemoptysis. Laboratory data revealed prolonged bleeding time and decreased platelet aggregation, suggesting that the patient had had a hemorrhagic diathesis associated with the administration of ticlopidine. Although many anti-thrombotic drugs have been recently employed in a variety of clinical cases, the patient's hemoptysis was considered to be due to side effects.
Wakunami
M
M
Department of Medicine, Kawasaki Medical School.
Umeki
S
S
Hashiguchi
K
K
Yagi
S
S
Kawane
H
H
Soejima
R
R
D002544:Cerebral Infarction / Q000517:prevention & control; D005260:Female; D006469:Hemoptysis / Q000139:chemically induced*; D006801:Humans; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects*; D012008:Recurrence; D013988:Ticlopidine / Q000009:adverse effects*
D010975:Platelet Aggregation Inhibitors; D013988:Ticlopidine