Evidence for aggregation of endothelin 1 in water.
In this report it is shown by CD spectroscopy that endothelin 1, when dissolved in water, is able to present intermolecular interactions leading to formation of aggregates. Surface tension and conductivity measurements suggest that the aggregation occurs through formation of micelles with a CMC of about 2.2 x 10(-5) M.
Bennes
R
R
UA 330 CNRS, Montpellier, France.
Calas
B
B
Chabrier
P E
PE
Demaille
J
J
Heitz
F
F
D002851:Chromatography, High Pressure Liquid; D002942:Circular Dichroism; D016232:Endothelins / Q000138:chemical synthesis / Q000737:chemistry*; D046911:Macromolecular Substances; D011487:Protein Conformation; D013500:Surface Tension; D014867:Water
D016232:Endothelins; D046911:Macromolecular Substances; D014867:Water