title: [Legionellosis].
abstract: Although increasing attention is being given to Legionella pneumonia in Japan, reports of solitary onset of this disease are scant in Japan. The patient, from whom L. dumoffii was isolated, was a 59-year-old male with no underlying disease. He visited our hospital because of fever and cough, and was admitted to our department for X-ray findings consistent with pneumonia. After admission, pulmonary lesions spread rapidly, and based on the suspicion of Legionella pneumonia, drugs such as EM, RFP and MINO were used. However, the patient died on the 26th hospital day. L. dumoffii was isolated from specimens obtained by airway aspiration before death and specimens of lung abscess and airway discharge obtained during autopsy (7 specimens in total). In addition, the L. dumoffii antibody titer in the serum became elevated. This is the first case of L. dumoffii pneumonia reported in Japan. The other case was in an 81-year-old male with underlying disease. He was admitted urgently with suspected pneumonia but died on the following day. L. pneumophila serogroup 5 was isolated from autopsied lung tissue. Fatality is high for this disease, making early diagnosis and treatment with appropriate antibiotics essential. Physicians should bear in mind the possibility of this disease and request the necessary laboratory tests in suspected cases without delay.
authors: Central Clinical Research Laboratory, Nissei Hospital, Osaka.
authors: I
authors: I
authors: Sano
authors: I
authors: I
authors: Fujita
authors: H
authors: H
authors: Tsuboi
authors: Y
authors: Y
authors: Murakami
authors: M
authors: M
authors: Nagata
authors: T
authors: T
authors: Yasui
authors: S
authors: S
authors: Konishi
authors: H
authors: H
authors: Akioka
authors: M
authors: M
authors: Hayashi
authors: M
authors: M
authors: Ohshima
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004917:Erythromycin / Q000008:administration & dosage; D006801:Humans; D007875:Legionella / Q000302:isolation & purification*; D007876:Legionellosis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D012293:Rifampin / Q000008:administration & dosage
chemical_list: D004917:Erythromycin; D012293:Rifampin