[Peritoneal oxygenation-dialysis as a temporary treatment of intestinal infarction].
The interval preceding the growth of irreversible lesions in an abdominal apoplexy is variable (3-48 hours). It may be used to improve the ischaemic viscus oxygenation, also compensating possible metabolic imbalances. 16 rabbits were used for research, in which apoplexy by the ligature of the arteria mesenterica superior was induced. Dialysis-oxygenation peritoneal treatment was carried out for 8 rabbits, the results of which were evaluated on the basis of the intestine macroscopic morphologic aspect; on the basis of the hematic phosphates values and in enteral biopsy. The oxygenation-dialysis produced a rapid improvement in enteral hue and in enteral motility, an important increase of PO2 and a reduction of hematic phosphates compared with the control group. Histologic examination did not show any significant variation. The attempt to increase general oxygenation by supplying PO2 via the peritoneum, was partly successful (10-15%). The aim of oxygenation the ischaemic enteral zone was successful. This due to elimination of CO2 and toxic products using dialysis. This simple method seems to be effective but further tests on swine would be necessary for clinical applications.
Aglietti
L
L
I Istituto di Clinica Chirurgica, Università degli Studi di Roma La Sapienza.
Mangialardi
N
N
Serrao
E
E
Occhigrossi
G
G
Soranna
V
V
Derme
G
G
Corteggiani
P
P
Cosenza
U M
UM
D000818:Animals; D003956:Dialysis; D008641:Mesenteric Vascular Occlusion / Q000097:blood / Q000473:pathology / Q000628:therapy*; D008642:Mesenteric Veins; D010100:Oxygen / Q000008:administration & dosage*; D010537:Peritoneum; D010710:Phosphates / Q000097:blood; D011817:Rabbits
D010710:Phosphates; D010100:Oxygen
L'ossigenazione-dialisi per via peritoneale come trattamento provvisorio dell'infarto dell'intestino.