The influence of peripheral connections on wallerian degeneration.
Following electrophysiological techniques we investigated whether wallerian degeneration of the cat sural nerve may be influenced by (1) its peripheral connection and (2) the distance from the cell body. Distal stumps connected to their innervation sites peripherally showed less degeneration than proximal ones when isolated between two sections. However, when two isolated adjacent segments were produced by making 3 sections, the resulting degeneration was more pronounced in the distal segment. Thus, both the factors mentioned above appear to influence wallerian degeneration.
Delgado-Lezama
R
R
Escuela Superior de Física y Matemáticas, Instituto Politécnico Nacional, México, D.F.
Muñoz-Martínez
E J
EJ
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D002415:Cats; D004558:Electric Stimulation; D013497:Sural Nerve / Q000033:anatomy & histology / Q000502:physiology*; D014855:Wallerian Degeneration / Q000502:physiology*