title: Thrombocytopenia following treatment with low doses of aminoglutethimide.
abstract: The authors report a case of severe thrombocytopenia during treatment with low doses of aminoglutethimide in a woman with advanced breast cancer. Hematologic toxicity secondary to aminoglutethimide did not seem to be dose-related, and an immunologic mechanism may be postulated. Although the incidence of the side effect is probably low, monitoring of blood counts during the first months of therapy is necessary.
authors: Medical Oncology Service of Internal Medicine Institute, General Hospital S. Maria, Terni, Italy.
authors: F
authors: F
authors: Di Costanzo
authors: M
authors: M
authors: Brugia
authors: D
authors: D
authors: Parriani
authors: R
authors: R
authors: Bartolucci
mesh_terms: D000616:Aminoglutethimide / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D013921:Thrombocytopenia / Q000139:chemically induced*
chemical_list: D000616:Aminoglutethimide