Hepatomegaly as a single presenting sign of stage IV-S neuroblastoma.
This article presents the case of an infant who on routine physical examination at the age of 5 months was found to have hepatomegaly. The initial investigation revealed borderline liver function tests, and ultrasonography showed multiple space-occupying lesions. Further workup using different imaging techniques, urinary vanillylmandelic acid, serum catecholamines, and liver biopsy led to the diagnosis of stage IV-S neuroblastoma. No primary site outside of the liver could be demonstrated. The tumor regressed spontaneously.
Bujanover
Y
Y
Department of Pediatrics, Rokach Hospital, Tel Aviv Medical Center, Sackler Faculty of Medicine, Israel.
Hareel
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A
Burstein
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Y
D006529:Hepatomegaly / Q000209:etiology*; D006801:Humans; D007223:Infant; D008297:Male; D009365:Neoplasm Regression, Spontaneous; D009367:Neoplasm Staging; D009447:Neuroblastoma / Q000150:complications / Q000175:diagnosis*