title: In vitro maturation of the exoerythrocytic stage of Plasmodium knowlesi observed under phase contrast microscopy.
abstract: Exoerythrocytic stages of Plasmodium knowlesi were obtained in primary culture of rhesus monkey hepatocytes. The development of a single parasite was followed with phase contrast microscopy until release of merozoites in slightly less than 5 days. This direct observation may offer opportunities to determine visually factors that may influence specific steps of schizont development.
authors: Malaria Branch, Centers for Disease Control, U.S. Department of Health and Human Services, Atlanta, Georgia 30333.
authors: P
authors: P
authors: Millet
authors: W E
authors: WE
authors: Collins
authors: C E
authors: CE
authors: Monken
authors: B G
authors: BG
authors: Brown
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D008099:Liver / Q000166:cytology / Q000469:parasitology; D008253:Macaca mulatta; D008858:Microscopy, Phase-Contrast; D010961:Plasmodium / Q000254:growth & development*