title: Selective parenteral and enteral antisepsis regimen (SPEAR).
abstract: With infection rates approaching 80% for patients staying in ICU for more than 5 days there is clearly a need for effective prophylaxis. SPEAR is a system of antimicrobial prophylaxis which extends the regimen of selective digestive tract decontamination to encompass systemic antimicrobial prophylaxis and includes oral non-absorbable antibacterial and antifungal agents with initial use of a broad-spectrum systemic antibacterial.
authors: City Hospital, Aberdeen.
authors: I M
authors: IM
authors: Gould
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D000935:Antifungal Agents / Q000008:administration & dosage*; D001424:Bacterial Infections / Q000517:prevention & control*; D004064:Digestive System / Q000382:microbiology; D004359:Drug Therapy, Combination; D006801:Humans; D007362:Intensive Care Units; D009181:Mycoses / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents