[Effects of indomethacin and BCG vaccine on growth of transplanted tumors in mice].
Continuous administration of indomethacin (IM) in drinking water (20 micrograms/ml) causes moderate inhibition of the growth of transplantable tumors in control mice but significantly increases the antitumor effect of BCG vaccine inoculated in combination with transplanted tumor cells. Hepatoma 29, insensitive to the vaccine becomes highly sensitivity to it under IM administration.
Kurunov
Iu N
IuN
Kaledin
V I
VI
D000230:Adenocarcinoma / Q000473:pathology* / Q000628:therapy; D000818:Animals; D001500:BCG Vaccine / Q000494:pharmacology* / Q000627:therapeutic use; D007213:Indomethacin / Q000494:pharmacology* / Q000627:therapeutic use; D008114:Liver Neoplasms, Experimental / Q000473:pathology* / Q000628:therapy; D008175:Lung Neoplasms / Q000473:pathology* / Q000628:therapy; D051379:Mice; D008808:Mice, Inbred CBA; D008815:Mice, Inbred Strains; D009368:Neoplasm Transplantation
D001500:BCG Vaccine; D007213:Indomethacin
Vliianie indometatsina i vaktsiny BTsZh na rost perevivnykh opukholeĭ u mysheĭ.