[Favorable outcome of Wegener's disease limited to the lungs. Apropos of a case].
A case of Wegener's granuloma limited to the lungs is reported in a 22 year old man. The pulmonary radiograph showed bilateral nodules. A lung biopsy of a nodule revealed a necrosing vasculitis involving the arteries and the veins and some areas of necrosis in geographical contours around these vessels. The renal function was normal and 4 1/2 years later the outcome remains favourable with the minimum of treatment, the exception being a course of antibiotics post operatively. Fifty seven cases of Wegener's granuloma limited to the lungs have been diagnosed after lung biopsy, transbronchial or bronchial material. The outcome was favourable in 72% of cases. This result was observed in the absence of any treatment in 6 cases (13%). In 2 cases the pulmonary nodules disappeared or developed cavities. In 4 cases the anatomical and/or radiological progress is unknown. Currently the factors leading to such an outcome have not yet been identified.
Justrabo
E
E
Laboratoire d'Anatomie Pathologique, Faculté de Médecine, Dijon.
Piard
F
F
Michiels
J F
JF
Reybet-Degat
O
O
Jacquot
J P
JP
Michiels
R
R
D000328:Adult; D014890:Granulomatosis with Polyangiitis / Q000473:pathology; D006801:Humans; D008168:Lung / Q000098:blood supply / Q000473:pathology; D008297:Male; D014657:Vasculitis / Q000473:pathology
Evolution favorable de la maladie de Wegener limitée aux poumons. A propos d'un cas.