title: Occurrence of cerebrohepatorenal (Zellweger) syndrome in the Karaite community in Israel: a genetic hypothesis.
abstract: Two infants with the cerebrohepatorenal (Zellweger) syndrome in Karaite families are described. This syndrome has an autosomal recessive mode of inheritance with an estimated incidence of between 1:25,000 and 1:100,000 live births. In addition to a previous report of the syndrome in a Karaite family, this report raises the possibility of a high incidence of Zellweger Syndrome among the Karaites in Israel.
authors: Department of Pediatrics A, Kaplan Hospital, Rehovot, Israel.
authors: A
authors: A
authors: Zung
authors: B M
authors: BM
authors: Mogilner
authors: R
authors: R
authors: Nissani
authors: Z
authors: Z
authors: Appelman
authors: Z
authors: Z
authors: Gelman de Kohan
mesh_terms: D000328:Adult; D003466:Cultural Characteristics; D005260:Female; D005787:Gene Frequency; D006801:Humans; D007231:Infant, Newborn; D007557:Israel; D007599:Judaism; D008297:Male; D010375:Pedigree; D015211:Zellweger Syndrome / Q000208:ethnology / Q000235:genetics*