title: Prism adaptation and other tasks involving spatial abilities in patients with Parkinson's disease, patients with frontal lobe lesions and patients with unilateral temporal lobectomies.
abstract: Patients in the early stages of Parkinson's disease were compared with patients who had sustained damage specific to either the frontal or temporal lobes and normal controls on a delayed alternation task, a test of the left right orientation and a prism adaptation task. On the former two tasks age accounted for more of the variability in performance than did site of brain lesion. However, patients with frontal lobe, right temporal lobe or basal ganglia damage were significantly impaired on the adaptation task. The results are discussed with regard to "switching", "sequencing" and "internal guidance" of movement hypotheses.
authors: Department of Experimental Psychology, Oxford, UK.
authors: A G
authors: AG
authors: Canavan
authors: R E
authors: RE
authors: Passingham
authors: C D
authors: CD
authors: Marsden
authors: N
authors: N
authors: Quinn
authors: M
authors: M
authors: Wyke
authors: C E
authors: CE
authors: Polkey
mesh_terms: D000328:Adult; D000368:Aged; D001288:Attention / Q000502:physiology; D001925:Brain Damage, Chronic / Q000503:physiopathology*; D001931:Brain Mapping; D004292:Dominance, Cerebral / Q000502:physiology; D004833:Epilepsy, Temporal Lobe / Q000601:surgery; D005260:Female; D005625:Frontal Lobe / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D009949:Orientation / Q000502:physiology*; D010300:Parkinson Disease / Q000503:physiopathology*; D010469:Perceptual Distortion / Q000502:physiology*; D011183:Postoperative Complications / Q000503:physiopathology*; D011340:Problem Solving; D011597:Psychomotor Performance / Q000502:physiology*; D011612:Psychosurgery; D011930:Reaction Time; D013702:Temporal Lobe / Q000503:physiopathology* / Q000601:surgery