title: [Evaluation of the efficacy of sanguinarine using the experimental gingivitis model].
abstract: Some studies showed positive results in testing the efficacy of sanguinarine delivered as oral rinse or dentifrice against plaque and gingivitis. The application of a gel containing 0.05 and 0.5% sanguinarine using special trays did not prevent plaque formation in regions with no oral hygiene. In contrast to placebo the 0.5% sanguinaria-gel was able to retard the formation of an experimental gingivitis. Chlorhexidine was superior to sanguinarine. Side effects were not detected.
authors: Sektion Stomatologie der Medizinischen Akademie Erfurt.
authors: A
authors: A
authors: Kurbad
authors: P
authors: P
authors: Gängler
authors: K
authors: K
authors: Kaufmann
mesh_terms: D000328:Adult; D000470:Alkaloids / Q000627:therapeutic use*; D053119:Benzophenanthridines; D002710:Chlorhexidine / Q000627:therapeutic use; D003773:Dental Plaque / Q000517:prevention & control*; D005891:Gingivitis / Q000628:therapy*; D006801:Humans; D007546:Isoquinolines
chemical_list: D000470:Alkaloids; D053119:Benzophenanthridines; D007546:Isoquinolines; C005705:sanguinarine; D002710:Chlorhexidine
vernacular_title: Prüfung von Sanguinaria-Alkaloiden am Modell der experimentellen Gingivitis.