title: Translocation t(1;17)(q12;q25) with a clinical picture like of a proximal deletion of 1q: identification by in situ hybridization with chromosome 1-specific satellite DNA probes.
abstract: The authors report a case of a balanced 1;17 translocation with breakpoints located in the secondary constriction of chromosome 1. This translocation is associated with pathological symptoms similar to those observed following a proximal deletion of 1q. We request contact with colleques who have observed similar, or related, cases of translocation with breakpoints in heterochromatic regions of human chromosomes.
authors: Institute of Pediatrics and Children's Surgery, MH of the USSR, Moscow.
authors: S G
authors: SG
authors: Vorsanova
authors: Y B
authors: YB
authors: Yurov
authors: M B
authors: MB
authors: Kurbatov
authors: L Z
authors: LZ
authors: Kazantzeva
mesh_terms: D002648:Child; D002871:Chromosome Banding; D002872:Chromosome Deletion; D002878:Chromosomes, Human, Pair 1; D002886:Chromosomes, Human, Pair 17; D015342:DNA Probes; D004276:DNA, Satellite / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D008297:Male; D009693:Nucleic Acid Hybridization; D014178:Translocation, Genetic
chemical_list: D015342:DNA Probes; D004276:DNA, Satellite