Prolonged survival of Pseudomonas cepacia in commercially manufactured povidone-iodine.
Pseudomonas cepacia organisms were recently recovered from a povidone-iodine antiseptic solution. During the subsequent investigation, laboratory studies were initiated to determine the survival time of these organisms in the iodophor solution, which contains 1% titratable iodine. The solution was sampled weekly upon receipt in our laboratory, and P. cepacia was subsequently recovered through 29 weeks of sampling. Current laboratory data and lot production date information from the manufacturer indicate that P. cepacia survived for up to 68 weeks from the time of manufacture. Scanning electron microscopic examination of contaminated solution demonstrated bacterial cells embedded in extracellular material.
Anderson
R L
RL
Nosocomial Infections Laboratory Branch, Centers for Disease Control, Atlanta, Georgia 30333.
Vess
R W
RW
Panlilio
A L
AL
Favero
M S
MS
D015169:Colony Count, Microbial; D004340:Drug Contamination; D006801:Humans; D008855:Microscopy, Electron, Scanning; D011206:Povidone-Iodine / Q000009:adverse effects / Q000494:pharmacology*; D011549:Pseudomonas / Q000187:drug effects* / Q000254:growth & development / Q000302:isolation & purification; D011552:Pseudomonas Infections / Q000209:etiology
D011206:Povidone-Iodine