Finding hydrophobic microdomains using an object-oriented database.
A procedure for finding clusters of adjacent residues in protein hydrophobic cores--hydrophobic microdomains--has been proposed by Plochocka et al. A program is presented that finds hydrophobic microdomains, making use of protein structure data stored in an object-oriented database and the list-processing features of Prolog. Alternative definitions for hydrophobic microdomains are explored. Results are presented for haemoglobin.
Kemp
G J
GJ
Department of Computing Science, University of Aberdeen, King's College, UK.
Gray
P M
PM
D000465:Algorithms; D006454:Hemoglobins / Q000737:chemistry; D046911:Macromolecular Substances; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*; D012984:Software; D012985:Software Design
D006454:Hemoglobins; D046911:Macromolecular Substances; D011506:Proteins