[Neurological symptoms and etiology of severely retarded children].
I identified forty-three patients with severe retardation aged 6-14 years in a defined community. More than half of the patients (23/43) had spastic tetraplegia and 9 had spastic diplegia. Only one case showed abnormal increase of muscle tone of dyskinetic type. The period when they had got underlying causes of their handicaps was as follows : congenital (acquired intrauterine, including intractable cases) 25, perinatal 6, and after the neonatal period 12. An increased proportion of congenital cases and a decreased proportion of perinatal cases are noted when the data were compared with previous reports. About a half of the total cases could be considered to be caused by preventable diseases such as perinatal anoxia, purulent meningitis, or intracranial hemorrhage due to vitamin K deficiency.
Suzuki
H
H
Division of Child Neurology, National Center Hospital for Mental, Nervous and Muscular Disorders, Tokyo.
D000293:Adolescent; D000367:Age Factors; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D001927:Brain Diseases / Q000150:complications; D002543:Cerebral Hemorrhage / Q000150:complications; D002648:Child; D005260:Female; D006801:Humans; D008607:Intellectual Disability; D008297:Male; D008581:Meningitis / Q000150:complications; D009122:Muscle Hypertonia / Q000209:etiology*; D010264:Paraplegia / Q000209:etiology*; D011782:Quadriplegia / Q000209:etiology*; D013492:Suppuration; D014057:Tomography, X-Ray Computed; D014813:Vitamin K Deficiency / Q000150:complications