title: Pathogenicity of attenuated peste des petits ruminants virus in sheep and goats.
abstract: Progressive loss of virulence for goat kids was noticed when peste des petits ruminants (PPR) virus was passaged in Vero cells. While goats inoculated with the 60th passage suffered from the clinical PPR disease and mortality, goats inoculated with the 80th passage did not show any sign of the disease. If the progressive loss of virulence of the virus with passage continues, it will not be long before a homologous PPR vaccine will be obtained at the National Veterinary Institute, Vom.
authors: Virology Division, National Veterinary Research Institute, Vom, Nigeria.
authors: F D
authors: FD
authors: Adu
authors: T
authors: T
authors: Joannis
authors: E
authors: E
authors: Nwosuh
authors: A
authors: A
authors: Abegunde
mesh_terms: D000818:Animals; D015511:Goat Diseases / Q000382:microbiology*; D006041:Goats; D009549:Nigeria; D012302:Rinderpest virus / Q000472:pathogenicity* / Q000502:physiology; D012756:Sheep; D012757:Sheep Diseases / Q000382:microbiology*; D014765:Viral Vaccines; D014774:Virulence
chemical_list: D014765:Viral Vaccines