[Effect of sucrose on lipid metabolism in rats: confirmation of the disaccharide effect].
Disaccharide effect of sucrose on lipid metabolism was confirmed in male Wistar rats (initial weight 119-127 g). The rats were given rations containing either sucrose (30% of total caloric++ value), or invert sugar, or starch only (control). The duration of the dietary period was 40 days. To study lipid metabolism the rats were injected i. p. with 1-14C-glucose and 3H-palmitic acid. 14C-radioactivity increased in the total lipid of serum and epididymal adipose tissue, in liver phospholipids and mostly in liver neutral lipids with the saccharose-supplemented diet but not with invert sugar-supplemented diet. In contrast, 3H-radioactivity in liver phospholipids decreased in rats that were given saccharose, no changes were recorded in the animals fed with invert sugar or starch.
Virovets
O A
OA
Sokolov
A I
AI
Gapparov
M M
MM
D000273:Adipose Tissue / Q000187:drug effects / Q000378:metabolism*; D000818:Animals; D004040:Dietary Carbohydrates / Q000008:administration & dosage / Q000494:pharmacology*; D005632:Fructose / Q000008:administration & dosage / Q000494:pharmacology; D005947:Glucose / Q000008:administration & dosage / Q000494:pharmacology; D006868:Hydrolysis / Q000187:drug effects; D050356:Lipid Metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013213:Starch / Q000008:administration & dosage / Q000494:pharmacology; D013395:Sucrose / Q000008:administration & dosage / Q000494:pharmacology*
D004040:Dietary Carbohydrates; D005632:Fructose; D013395:Sucrose; D013213:Starch; C008133:invert sugar; D005947:Glucose
Osobennosti vliianiia sakharozy na metabolizm lipidov u krysy: podtverzhdenie disakharidnogo éffekta.