[Systemic candidiasis and ureteral fungus ball. Ketoconazole and irrigating solutions in the management of urinary candidiasis].
A case of systemic candidiasis is presented in a patient with one kidney in the post-operative period from a cysto-prostatouretrectomy with Bricker ureteroileal derivation, performed due to multifocal superficial vesical tumour non controllable by endoscopy. The clinical picture developed with anuria and temporary diuresis periods associated to a severe septic picture; a deep Candida albicans infection was demonstrated by laboratory tests and a fungus ball ureteral obstruction was demonstrated by radiology. Urinary derivation by means of percutaneous nephrostomy, associated with oral treatment with ketoconazole and local treatment with amphotericin B solution intermittently irrigated through the nephrostomy allowed the patient's resuperation and the fungus ball was spontaneously ejected after 30 days of treatment. The different forms of presentation of urinary candidiasis are discussed together with the diagnostic methods and present therapeutical options, with special reference to the imidazole derivative ketoconazole and irrigation solutions.
Martínez Bengoechea
J
J
Servicio de Urología, Hospital Miguel Servet, Zaragoza, España.
Allepuz Losa
C
C
Gil Sanz
M J
MJ
Minguez Pemán
J
J
Rioja Sanz
L A
LA
D000666:Amphotericin B / Q000627:therapeutic use*; D002177:Candidiasis / Q000150:complications / Q000188:drug therapy*; D003131:Combined Modality Therapy; D006801:Humans; D007654:Ketoconazole / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009403:Nephrostomy, Percutaneous; D011183:Postoperative Complications / Q000628:therapy; D007507:Therapeutic Irrigation; D014517:Ureteral Obstruction / Q000382:microbiology* / Q000628:therapy*
D000666:Amphotericin B; D007654:Ketoconazole
Candidiasis sistémica y fungus ball ureteral. Ketoconazol y soluciones irrigantes en el manejo de la candidiasis urinaria.