[The Binder syndrome and goniodysgenesis. Apropos of a case].
A 15 years old boy was deferred to our department with growth hormone deficiency, deafness with middle ear bones involvement, and a facial dysmorphy called Binder syndrome. He presented ocular abnormalities with juvenile glaucoma and iris anterior insertion and goniodysgenesis. All these pathologic features are linked with the development of the neural crests. In our knowledge, it is the first so complete clinical association reported, which emphasizes the important role of the neural crest cells in early organogenesis.
Bron
A
A
Service d'Ophtalmologie, Hôpital Jean-Minjoz, Besançon.
Bertrand
A M
AM
Chabod
C
C
Royer
J
J
D000015:Abnormalities, Multiple / Q000196:embryology*; D000328:Adult; D005147:Facial Bones / Q000002:abnormalities / Q000196:embryology; D005901:Glaucoma / Q000151:congenital* / Q000196:embryology*; D006801:Humans; D008297:Male; D009432:Neural Crest / Q000196:embryology*; D013131:Spine / Q000002:abnormalities / Q000196:embryology; D013577:Syndrome
Syndrome de Binder et goniodysgénésies. A propos d'un cas.