title: A study of the mutagenicity of some commercially canned Spanish mushrooms.
abstract: The mutagenicity of two wild (Lactarius deliciosus and Boletus luteus) and two cultivated (Agaricus bisporus and Pleurotus ostreatus) mushrooms, preserved by canning and widely consumed in Spain, was studied in the Ames Salmonella/microsome test and in the CHO/HPRT assay system using mammalian cells. The mushroom extracts did not show mutagenicity in the microbial Ames test nor in the mammalian CHO-K1 cells, and this response was not modified by the presence of S-9 mix in the assay mixtures. Only the extracts from P. ostreatus showed a weak mutagenic activity in the CHO/HPRT assay in the presence of a metabolic activation system (S-9).
authors: Departamento de Higiene y Tecnología de los Alimentos, Facultad de Veterinaria, Universidad Complutense, Madrid, Spain.
authors: P
authors: P
authors: Morales
authors: E
authors: E
authors: Bermúdez
authors: B
authors: B
authors: Sanz
authors: P E
authors: PE
authors: Hernández
mesh_terms: D000818:Animals; D001487:Basidiomycota; D002478:Cells, Cultured / Q000187:drug effects; D006224:Cricetinae; D003412:Cricetulus; D005260:Female; D008099:Liver / Q000187:drug effects*; D009152:Mutagenicity Tests; D009183:Mycotoxins / Q000633:toxicity*; D051381:Rats; D011919:Rats, Inbred Strains; D012486:Salmonella typhimurium / Q000187:drug effects; D013030:Spain
chemical_list: D009183:Mycotoxins