[Role of growth hormone in proliferative diabetic retinopathy. Clinical and immunohistochemical aspects].
The first part of this work deals with the various therapeutics with pituitary aims on ten patients with proliferative retinopathy. In the second part, the Growth Hormone involvement is considered, by the mean of IGF-I dosages in the serum and the vitreous of diabetic and non-diabetic patients. IGF-I is also sought in neovascular membranes by immunohistological methods. If radioimmunological dosages are negative, IGF-I deposits are found into new vessels wall. The significance of these immunohistological findings remains to be determined.
Negre
F
F
Hôpital Saint-Roch, Service d'Ophtalmologie, Nice.
Fredj-Reygrobellet
D
D
Harroche
S
S
Taieb
J C
JC
D000328:Adult; D003930:Diabetic Retinopathy / Q000378:metabolism* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D007334:Insulin-Like Growth Factor I / Q000032:analysis*; D008297:Male; D014822:Vitreous Body / Q000737:chemistry
D007334:Insulin-Like Growth Factor I
Rôle de l'hormone de croissance dans les rétinopathies diabétiques prolifératives. Aspects cliniques et immunohistochimiques.