Kinetic parameters in the growth plate of normal and achondroplastic (cn/cn) mice.
We have reinvestigated the overall size, zone size, mitotic rate and growth rate in the tibial epiphysis of normal and achondroplastic (cn/cn) mice aged 7-55 days. Our present sample did not contain the two phenotypes characteristic of some stocks carrying the gene: cn/cn mice showed smaller zone sizes within the growth plates, smaller cells, decreased mitotic indices and growth rates.
Sannasgala
S S
SS
Department of Anatomy, University of Leeds, West Yorks, UK.
Johnson
D R
DR
D000130:Achondroplasia / Q000473:pathology*; D000818:Animals; D006132:Growth Plate / Q000033:anatomy & histology / Q000254:growth & development / Q000473:pathology*; D006984:Hypertrophy / Q000473:pathology; D051379:Mice; D008817:Mice, Mutant Strains; D008938:Mitosis; D013977:Tibia / Q000254:growth & development / Q000473:pathology