[Acquired paraneoplastic hypertrichosis lanuginosa associated with scleroderma].
Acquired hypertrichosis lanuginosa is universally recognized as an individual disease and seldom reported as a genuine paraneoplastic manifestation. We report the case of a 30-year old woman with acquired hypertrichosis lanuginosa. Due to the finding of a cervical lymph node metastasis, she was investigated for an internal neoplasm, but the original tumour could not be found by the usual methods. A bronchogenic carcinoma was discovered at autopsy. Beside hypertrichosis, this patient had other disorders not described in the literature as associated with that disease, viz.: progressive systemic scleroderma, fissured and hyperpigmented tongue, thrombocytopenia, galactorrhoea, axillary and pubic alopecia and overcurvature of toe nails. A review of similar cases in the literature provided clinical arguments in favour of the hormonal origin of this paraneoplastic hypertrichosis.
Valda Rodriguez
L
L
Service de dermatologie, Hospital de Clinicas, Universitario, La Paz, Bolivia.
Torrico Velasco
J
J
Zeballos Vasconcellos
R
R
D000328:Adult; D002283:Carcinoma, Bronchogenic; D005260:Female; D005687:Galactorrhea / Q000150:complications; D006801:Humans; D006983:Hypertrichosis / Q000150:complications* / Q000473:pathology; D008175:Lung Neoplasms; D010257:Paraneoplastic Syndromes / Q000150:complications*; D012595:Scleroderma, Systemic / Q000150:complications*; D013921:Thrombocytopenia / Q000150:complications; D014060:Tongue Diseases / Q000150:complications
Hypertrichose lanugineuse acquise paranéoplasique associée à sclérodermie.