Complete spontaneous regression of multiple basal cell carcinomas in the basal cell nevus syndrome: the possible role of transepithelial elimination.
A 36-year-old Latin American man with the basal cell nevus syndrome had multiple, soft, hairless, depressed scars of the face, scalp, neck, and back, ranging in size from 0.3 x 0.5 cm to 3.5 x 3.9 cm. These areas had never been treated and previously were sites of basal cell carcinomas that underwent complete spontaneous regression 4-5 years from the date of onset. Pathology of these spontaneously regressed sites was consistent with the criteria established by Curson and Weedon (1979). Type III transepithelial elimination was demonstrated for a basal cell carcinoma. Type III transepithelial elimination may play a role in the spontaneous regression of basal cell carcinomas.
Kelley
R S
RS
Department of Pathology, University of Texas Medical Branch, Galveston 77550.
Wagner
R F
RF
Sanchez
R L
RL
Duff
R R
RR
D000328:Adult; D001478:Basal Cell Nevus Syndrome / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D005153:Facial Neoplasms / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D008297:Male; D015580:Mohs Surgery; D012075:Remission, Spontaneous