[Tiaprofenic acid: a clinical study of 1186 patients with inflammatory ORL diseases].
A multicenter trial is presented involving 39 Italian university and hospital centers and 1186 patients (mean age 37.6 +/- 0.46 years) suffering from phlogistic aural (33.7%), rhino-sinusal (22.5%) or pharyngolaryngeal (43.8%) pathology. These patients were treated with 600 mg of tiaprofenic acid daily for a period of 7 days. The drug was administered either as monotherapy (53.2% of the cases) or in association with antibiotics (46.8%). Tiaprofenic acid showed similar therapeutic efficacy under both conditions, carrying out a clear antipyretic, anti-inflammatory, mainly analgesic action in the pathologies of all three otolaryngological areas. Treatment tolerance and compliance proved quite good. Only 20% of the patients claimed light side effects. The treatment was interrupted only in 18 (1.5%) of the 1186 patients studied.
Marcucci
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Divisione ORL, Ospedale Grande degli Infermi di Viterbo.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D010038:Otorhinolaryngologic Diseases / Q000188:drug therapy*; D011422:Propionates / Q000008:administration & dosage / Q000627:therapeutic use*
D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D011422:Propionates; C021270:tiaprofenic acid
Acido tiaprofenico: studio clinico su 1186 pazienti con forme flogistiche di pertinenza otorinolaringoiatrica.