Nucleosome unit repeat size in aneuploid mice.
Male 8-day-old mice that have part of chromosome 7 translocated to an X chromosome [T(X;7)1 Ct] and that are chromosomally unbalanced for chromosome 7, and consequently trisomic for that part of chromosome 7, were found to have a smaller nucleosome repeat unit size than normal littermate males (Rake, A. V., and Edwards, R. H., Biochem. Genet. 25:671, 1987). This smaller nucleosome size is maintained in adult trisomic males. Males with a balanced chromosomal translocation [T(X;7)1Ct] had a normal nucleosome size compared to their littermates. The nucleosome unit size is not altered in two other types of aneuploid mice studied (XO vs XX, 2n = 39 and 40, respectively; and Ts12(17) vs normal, 2n = 40 and 41, respectively).
Rake
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Biological Sciences, Wright State University, Dayton, Ohio 45435.
D000782:Aneuploidy; D000818:Animals; D002875:Chromosomes / Q000737:chemistry*; D005260:Female; D008098:Litter Size; D008297:Male; D051379:Mice / Q000235:genetics*; D009707:Nucleosomes / Q000737:chemistry*; D009928:Organ Specificity; D012091:Repetitive Sequences, Nucleic Acid; D014178:Translocation, Genetic
D009707:Nucleosomes