Heterogeneity in chemotaxis of neutrophils with different densities.
We investigated N-formyl-Methionyl-Leucyl-Phenylalanine (fMLP)-induced chemotaxis of neutrophils with different densities. FMLP-induced (10(-8)M) chemotaxis of neutrophils with lower density were significantly reduced when compared to neutrophils with higher density (p less than 0.05). These findings imply a relationship between the neutrophil density and chemotaxis.
Miyagawa
H
H
Allergic Disease Center, Creighton University, Omaha, Nebraska.
Okada
C
C
Sugiyama
H
H
Hopp
R J
RJ
Bewtra
A K
AK
Townley
R G
RG
D000328:Adult; D002634:Chemotaxis, Leukocyte / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D009240:N-Formylmethionine Leucyl-Phenylalanine / Q000008:administration & dosage / Q000494:pharmacology*; D009504:Neutrophils / Q000187:drug effects / Q000276:immunology*
D009240:N-Formylmethionine Leucyl-Phenylalanine