[Distribution of labeled amino acids and delta-sleep inducing peptide in the body after instillation into the conjunctiva of the rabbit eye].
Dynamics of 3H-valine, 3H-glycine and 3H-DSIP distribution in various brain structures, tissues and liquids of an organism due to administration of these substances in eye conjunctive were studied in rabbits with scintillation spectrometry method. Marked amino acids and DSIP were observed in all substrates in 10 min after administration. Maximal activity was found in 2 h in the brain visual cortex and in 30 min in cardiac tissue, spleen and optical chiasma.
Badikov
V I
VI
Gitel'
E P
EP
Ivanova
N Ia
NIa
Ivolgina
L G
LG
Fedianina
M G
MG
Zaĭtsev
D A
DA
Miasoedov
N F
NF
Sudakov
K V
KV
D000596:Amino Acids / Q000008:administration & dosage / Q000378:metabolism*; D000818:Animals; D003228:Conjunctiva; D003701:Delta Sleep-Inducing Peptide / Q000008:administration & dosage / Q000378:metabolism*; D005998:Glycine / Q000378:metabolism; D007322:Instillation, Drug; D007553:Isotope Labeling; D009206:Myocardium / Q000378:metabolism; D009897:Optic Chiasm / Q000378:metabolism; D011817:Rabbits; D013154:Spleen / Q000378:metabolism; D014018:Tissue Distribution; D014316:Tritium; D014633:Valine / Q000378:metabolism; D014793:Visual Cortex / Q000378:metabolism*
D000596:Amino Acids; D014316:Tritium; D003701:Delta Sleep-Inducing Peptide; D014633:Valine; D005998:Glycine
Raspredelenie mechenykh aminokislot i peptida, vyzyvaiushchego del'ta-son, v organizme pri instiliatsii na kon"iunktivu glaza krolika.