title: Chemotherapy of breast cancer in Nigerians: side-effects and quality of life.
abstract: Fifty-seven breast cancer patients under follow-up between 1987 and 1988 at the Radiotherapy Department, Lagos University Teaching Hospital following mastectomy and radiotherapy were given combination chemotherapy as adjuvant therapy or as a result of recurrent disease. With the use of a detailed questionnaire the side-effects and reactions to chemotherapy were assessed. Apart from disturbances of menstruation in 24 (53.3%) of the 45 premenopausal patients, the majority of patients tolerated treatment very well, whilst the side-effects that occurred were limited. Nigerian women may be more tolerant to the side-effects of chemotherapy than those women living in developed countries.
authors: Department of Radiation Biology and Radiotherapy, College of Medicine, University of Lagos, Nigeria.
authors: K K
authors: KK
authors: Ketiku
authors: A T
authors: AT
authors: Ajekigbe
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy*; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000009:adverse effects; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects; D008875:Middle Aged; D011788:Quality of Life
chemical_list: D003520:Cyclophosphamide; D005472:Fluorouracil; D008727:Methotrexate