[Clinical significance of serum bile acid determination in liver diseases].
The recent availability of radioimmunological and enzymatic kits to measure serum bile acids (SBA) has allowed diffusion of this laboratory test. The aim of this paper is to provide an assessment of diagnostic and prognostic significance of SBA in liver cirrhosis, on the basis of the most recent data available to us. Measurement of these substances in serum does not appear to be very useful either in screening or in differential diagnosis of liver disorders, since it seems unable to provide further information with respect to commonly used parameters. On the contrary, SBA show a remarkable predictive value both in chronic active hepatitis and in liver cirrhosis. SBA measurement may therefore become a useful tool in planning the therapeutic approach to these hepatic diseases.
Siciliano
M
M
Istituto di Patologia Speciale Medica, Facoltà di Medicina e Chirurgia, Università Cattolica del S. Cuore, Roma.
Lorenzin
F
F
Milani
A
A
Rossi
L
L
D001647:Bile Acids and Salts / Q000097:blood*; D006521:Hepatitis, Chronic / Q000097:blood / Q000175:diagnosis; D006801:Humans; D008103:Liver Cirrhosis / Q000097:blood / Q000175:diagnosis; D008107:Liver Diseases / Q000097:blood* / Q000175:diagnosis; D011379:Prognosis
D001647:Bile Acids and Salts
Significato clinico del dosaggio degli acidi biliari sierici nelle epatopatie.