Models for skin tumour risks in workers exposed to mineral oils.
The relationship between skin tumours in man and exposure to polyaromatic hydrocarbons has been studied in lathe operators exposed to cutting oils. Seven cases of scrotal cancer and 13 cases of senile keratosis and keratoacanthoma were observed. The risk varied as the 1.6th power of duration of exposure for cancer on the scrotum and the 2.4th power for tumours on the hand and forearms. These results accord well with experiments on animals. There was some evidence of an increasing trend in risk with increasing age at first exposure.
Järvholm
B
B
Department of Occupational Medicine, Sahlgren University Hospital, Göteborg, Sweden.
Easton
D
D
D000328:Adult; D000367:Age Factors; D000368:Aged; D005542:Forearm; D006801:Humans; D008297:Male; D008875:Middle Aged; D008899:Mineral Oil / Q000009:adverse effects*; D009784:Occupational Diseases / Q000139:chemically induced*; D016273:Occupational Exposure; D011083:Polycyclic Compounds / Q000009:adverse effects*; D012306:Risk; D012611:Scrotum; D012878:Skin Neoplasms / Q000139:chemically induced*
D011083:Polycyclic Compounds; D008899:Mineral Oil