title: Cloning and sequencing of human LH/hCG receptor cDNA.
abstract: We have isolated and sequenced a cDNA encoding the human luteinizing hormone--choriogonadotropin (LH/hCG) receptor. The deduced amino acid sequence (699 residues) containing seven putative transmembrane segments displays sequence similarity to G protein-coupled receptors. The receptor consists of 335 residue extracellular domain which contains six N-linked glycosylation sites. While the protein is 85 and 87% identical overall with the previously cloned rat and porcine LH/hCG receptor respectively, the most highly conserved regions are the putative transmembrane segments (91 and 94% similarity, respectively).
authors: Department of Obstetrics and Gynecology, Gunma University School of Medicine, Japan.
authors: T
authors: T
authors: Minegishi
authors: K
authors: K
authors: Nakamura
authors: Y
authors: Y
authors: Takakura
authors: K
authors: K
authors: Miyamoto
authors: Y
authors: Y
authors: Hasegawa
authors: Y
authors: Y
authors: Ibuki
authors: M
authors: M
authors: Igarashi
authors: T ]
authors: T]
authors: Minegish T [corrected to Minegishi
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000737:chemistry; D006801:Humans; D008969:Molecular Sequence Data; D051381:Rats; D011974:Receptors, LH / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D013552:Swine
chemical_list: D011974:Receptors, LH; D004247:DNA