[Bronchiolitis obliterans, pneumocystosis and HIV infection].
A 39 year old man who was HIV positive and was treated with trimethoprim-sulfamethoxazole for pneumocystis with hypoxaemia. During the acute episode he had a persistent fever of 38 degrees and hypoxaemia with a PaO2 of 65 mm/Hg and bilateral opacities both radiologically and on a CT scan, which were of alveolar type, with bronchograms identical to those observed before the treatment of the pneumocystis. In view of the negative evidence for a respiratory or extra respiratory infection, a surgical biopsy was performed and this revealed lesions of bronchiolitis obliterans with an organising pneumonia (BOOP). After the thoracotomy, there was a spontaneous clinical cure in a few days and radiological clearance in a month. This very rare diagnosis should be added to the list of causes of alveolar pneumopathy with infiltration and fever occurring during the course of an HIV infection.
Liote
H
H
Service de Pneumologie et Réanimation Respiratoire, Groupe Hospitalier Pitié-Salpêtrière, Paris.
Porte
J M
JM
Postal
M J
MJ
Martin de Lassalle
E
E
Derenne
J P
JP
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D001706:Biopsy; D001980:Bronchi / Q000473:pathology; D001989:Bronchiolitis Obliterans / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D011020:Pneumonia, Pneumocystis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D014057:Tomography, X-Ray Computed
Bronchiolite oblitérante, pneumocystose et infection par le V.I.H.