Treatment of recurrent common warts with one low dose of intralesional natural human leukocyte interferon alpha.
Nine patients with recurrent and long lasting common warts were treated with intralesional Hu-IFN-alpha. The schedule was a single dose per wart, ranged between 10(5) and 2 x 10(5) IU. Placebo was also administered in 3 of these patients. Complete remission was observed in 7 of the 9 patients. The pattern of warts involution and the possible interferon mechanism of action are discussed. A significant pain relief, produced by interferon injection was observed in the patients with plantar warts and in one patient with subungueal wart.
Pueyo
S
S
Dermatologic Unit Children's Hospital, San Isidro, Argentina.
Criscuolo
M
M
Davidovich
C
C
Zorzópulos
J
J
Pesce
A
A
Díaz
A
A
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D007370:Interferon Type I / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D012008:Recurrence; D014860:Warts / Q000628:therapy*
D007370:Interferon Type I