title: Neutropenic enterocolitis in a patient with ovarian cancer after treatment with high-dose carboplatin and granulocyte macrophage-colony stimulating factor (GM-CSF).
abstract: A 50-yr-old women is described with relapsed ovarian cancer. She developed neutropenic enterocolitis after treatment with high-dose carboplatin (1000 mg/m2) and granulocyte macrophage-colony stimulating factor (GM-CSF). The clinical features and the pathogenesis of neutropenic enterocolitis are discussed. This case is the first report of neutropenic enterocolitis associated with the treatment of carboplatin.
authors: Department of Internal Medicine, The Netherlands Cancer Institute, Amsterdam.
authors: L T
authors: LT
authors: Vlasveld
authors: W W
authors: WW
authors: Ten Bokkel Huinink
authors: S
authors: S
authors: Rodenhuis
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D016190:Carboplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004760:Enterocolitis / Q000139:chemically induced*; D005260:Female; D006801:Humans; D016173:Macrophage Colony-Stimulating Factor / Q000008:administration & dosage; D008875:Middle Aged; D009503:Neutropenia / Q000139:chemically induced*; D010051:Ovarian Neoplasms / Q000188:drug therapy*
chemical_list: D016173:Macrophage Colony-Stimulating Factor; D016190:Carboplatin