title: [Immune response to a synthetic polysaccharide and protein conjugate].
abstract: Synthetic polysaccharide (S-PS) containing aglycone-spacer with a free amino group was really alpha 1,6-mannan with Cn approximately 10. S-PS was transformed into isothiocyanate derivative by treating it with thiophosgene and engaged into reaction with amino group of bovine serum albumin (BSA) lysine residues. Rabbits were immunized with S-PS-BSA conjugate and antibodies to S-PS titres were estimated by means of ELISA. S-PS-BSA conjugate was proved to provoke specific anti-polysaccharide antibodies formation in rabbits.
authors: T A
authors: TA
authors: Makarenko
authors: N A
authors: NA
authors: Kocharova
authors: Iu E
authors: IuE
authors: Tsvetkov
authors: L S
authors: LS
authors: Edvabnaia
authors: Iu A
authors: IuA
authors: Knirel'
authors: L V
authors: LV
authors: Bakanovskiĭ
authors: E V
authors: EV
authors: Kholodkova
authors: E S
authors: ES
authors: Stanislavskiĭ
authors: N K
authors: NK
authors: Kochetkov
mesh_terms: D000818:Animals; D000906:Antibodies / Q000032:analysis; D000917:Antibody Formation; D000941:Antigens / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D011134:Polysaccharides / Q000276:immunology*; D011817:Rabbits; D012710:Serum Albumin, Bovine / Q000276:immunology*
chemical_list: D000906:Antibodies; D000941:Antigens; D011134:Polysaccharides; D012710:Serum Albumin, Bovine
vernacular_title: Immunnyĭ otvet k kon"iugatu sinteticheskogo polisakharida s belkom.