[An ultrastructural study of the optic papilla in experimental hypotony].
The ultrastructures of the optic papilla at different intervals during experimental hypotony in rabbits were studied by transmission electron microscopy, with the results that after 14 days the axons of optic nerve fibers showed signs of degeneration; after 21 days there appeared marked pathological changes, and after 30 days there were serious irreversible pathological changes. These findings suggest that clinical hypotony, such as occurs after glaucoma operations particularly, should be duly attended to.
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Department of Ophthalmology, Third Affiliated Hospital, Hebei Medical College, Shijiazhuang, Hebei, Province.
D000818:Animals; D008854:Microscopy, Electron; D015814:Ocular Hypotension / Q000473:pathology*; D009898:Optic Disk / Q000648:ultrastructure*; D011817:Rabbits; D013997:Time Factors