title: [Cefuroxime axetil (Zinnat)--laboratory and clinical study].
abstract: The authors investigated the antibacterial action of cefuroxim in vitro and proved its relatively broad spectrum of action. Administration of the esterified form, Zinnat, produced very satisfactory therapeutic concentrations of cefuroxim in serum, bile tissue of operated gallbladders. The prophylactic administration of the combined parenteral and oral form of cefuroxim proved excellent in biliary surgery in twenty patients.
authors: Katedra chirurgie LFH UK, Praha.
authors: F
authors: F
authors: Vyhnánek
authors: M
authors: M
authors: Hejzlar
authors: M
authors: M
authors: Procházka
authors: T
authors: T
authors: Pellar
authors: L
authors: L
authors: St'astná
authors: J
authors: J
authors: Silarová
authors: E
authors: E
authors: Kittnar
authors: T
authors: T
authors: Vedral
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002444:Cefuroxime / Q000031:analogs & derivatives* / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use; D002763:Cholecystectomy; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011292:Premedication; D011355:Prodrugs / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D011355:Prodrugs; D002444:Cefuroxime; C040738:cefuroxime axetil
vernacular_title: Axetil cefuroxim (Zinnat)--laboratorní a klinické studie.