[The effect of prednisolone on the immunoglobulin content of the blood in patients with disseminated sclerosis].
The authors examined the dynamics of IgA, IgM, IgG in the blood of 100 patients with multiple sclerosis. Of them 50 patients received complex treatment in combination with prednisolone. Comparison of indices of concentration of serum immunoglobulins revealed a distinct reduction of their level of all classes in patients with multiple sclerosis, especially in those receiving prednisolone. Prednisolone produced an unfavourable effect on the course of the demyelinating process in patients with multiple sclerosis.
Iarosh
A A
AA
Prokopiv
M M
MM
Zhovnir
I K
IK
Kanevskaia
S A
SA
D000328:Adult; D000917:Antibody Formation / Q000187:drug effects / Q000276:immunology; D003131:Combined Modality Therapy; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D009103:Multiple Sclerosis / Q000188:drug therapy* / Q000276:immunology; D011239:Prednisolone / Q000009:adverse effects / Q000627:therapeutic use*; D011379:Prognosis
D007136:Immunoglobulins; D011239:Prednisolone
Vliianie prednizolona na soderzhanie immunoglobulinov v krovi bol'nykh rasseiannym sklerozom.