[Effects of bronchial secretions of patients with bronchial asthma and chronic bronchitis on the motility of ciliated cells of the ciliated epithelium].
It has been shown that bronchial mucus from patients with bronchial asthma and chronic bronchitis can produce a ciliostatic effect when incubated with strips of frog palate mucosa. This effect can more often be found during clinical exacerbation and is supposed to be reversible. The ciliostatically active samples of bronchial mucus taken from asthmatic patients markedly inhibit reactivation glycerol models of frog's ciliated epithelium. It can therefore be suggested that the found activity acts directly on tubulin-dynein complex of the cilia. In contrast to these findings, the ciliostatically active samples of bronchial of glycerol models and therefore possibly act through some other mechanism.
Shanina
N A
NA
Dykhanov
I I
II
D000818:Animals; D001249:Asthma / Q000503:physiopathology*; D001980:Bronchi / Q000378:metabolism*; D001991:Bronchitis / Q000503:physiopathology*; D002908:Chronic Disease; D002923:Cilia / Q000502:physiology*; D004848:Epithelium / Q000502:physiology; D006801:Humans; D009079:Mucociliary Clearance; D011898:Ranidae
Vliianie bronkhial'nogo sekreta bol'nykh bronkhial'noĭ astmoĭ i khronicheskim bronkhitom na podvizhnost' resnichek kletok mertsatel'nogo épiteliia.