title: Angiotensin-converting enzyme inhibitors in pregnancy may result in neonatal renal failure.
abstract: Oligohydramnios and neonatal renal failure is reported in a premature infant whose mother had used enalapril in weeks 32-35 of her pregnancy. The infant recovered adequate renal function after peritoneal dialysis. Review of the literature supports our view that angiotensin-converting enzyme inhibitors should not be used in pregnancy; if they are, both mother and fetus should be monitored with extreme care.
authors: Department of Paediatrics and Child Health, University of the Witwatersrand, Johannesburg Hospital.
authors: S A
authors: SA
authors: Hulton
authors: P D
authors: PD
authors: Thomson
authors: P A
authors: PA
authors: Cooper
authors: A D
authors: AD
authors: Rothberg
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced*; D004656:Enalapril / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy*
chemical_list: D004656:Enalapril