Hydroxyurea-induced acute alveolitis in a patient with chronic myeloid leukaemia.
A number of cytotoxic agents have been implicated in the production of widespread pulmonary alveolar damage. We present a case of life-threatening alveolitis in a patient on hydroxyurea for chronic myeloid leukaemia. The clinical course suggests that the alveolitis was induced by the hydroxyurea. This is the first reported case of hydroxyurea-induced pulmonary alveolitis.
Jackson
G H
GH
Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne, UK.
Wallis
J
J
Ledingham
J
J
Lennard
A
A
Proctor
S J
SJ
D000368:Aged; D000542:Alveolitis, Extrinsic Allergic / Q000139:chemically induced* / Q000000981:diagnostic imaging; D006801:Humans; D006918:Hydroxyurea / Q000009:adverse effects*; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy*; D008297:Male; D011859:Radiography
D006918:Hydroxyurea