title: Treatment of cerebral coenuriosis in sheep with praziquantel.
abstract: Sheep (n = 14) with coenuriosis were treated with praziquantel in single or divided doses at total dosage rates of 50 to 500 mg kg-1 live mass. Nine of the sheep also received corticosteroid, diuretic and analgesic supportive therapy. Stress was avoided as far as practically possible. Treatment of one sheep with acute coenuriosis at a total dosage rate of 500 mg kg-1 praziquantel, was unsuccessful. Eight sheep were successfully treated at total dosages ranging from 100 to 500 mg kg-1 live mass, whereas dosages of 50 mg kg-1 were successful in 2 sheep only. Dosages of 50 mg kg-1 in 2 other sheep with multiple cerebral coenuri, were unsuccessful or only partially successful in killing parasites.
authors: Department of Parasitology, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, Republic of South Africa.
authors: A
authors: A
authors: Verster
authors: R C
authors: RC
authors: Tustin
mesh_terms: D000208:Acute Disease; D000818:Animals; D001927:Brain Diseases / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D002908:Chronic Disease; D010865:Pilot Projects; D011223:Praziquantel / Q000008:administration & dosage* / Q000627:therapeutic use; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy*; D013622:Taeniasis / Q000188:drug therapy / Q000662:veterinary*
chemical_list: D011223:Praziquantel