A novel synthesis of xanthines: support for a new binding mode for xanthines with respect to adenosine at adenosine receptors.
Peet
N P
NP
Merrell Dow Research Institute, Cincinnati, Ohio 45215.
Lentz
N L
NL
Meng
E C
EC
Dudley
M W
MW
Ogden
A M
AM
Demeter
D A
DA
Weintraub
H J
HJ
Bey
P
P
D000241:Adenosine / Q000378:metabolism*; D000818:Animals; D004285:Dogs; D006801:Humans; D008968:Molecular Conformation; D015394:Molecular Structure; D011485:Protein Binding; D051381:Rats; D011983:Receptors, Purinergic / Q000378:metabolism*; D013329:Structure-Activity Relationship; D013806:Theophylline / Q000737:chemistry / Q000378:metabolism; D014970:Xanthines / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism*
D011983:Receptors, Purinergic; D014970:Xanthines; D013806:Theophylline; D000241:Adenosine