Diagnostic efficacy of physical examination, mammography, fine needle aspiration cytology (triple-test) in solid breast lumps: an analysis of 1708 consecutive cases.
The clinical-radiologic-cytologic triplet was used for diagnostic evaluation in 1708 women over 30 years old with a breast lump. All the lumps were subjected to surgery except for 258 cases in which clinical resolution took place within 1-2 months. Seven-hundred and ninety-three out of 1450 nodules removed were cancers. Sensitivity of the clinical, mammographic and cytologic examinations was 82%, 73% and 68%, respectively. It increased to 95% when they were associated. Specificity was 63%, 80% and 97%, respectively. The predictive value of positive results of the triple test was 100%. No patient with malignant cytology was subsequently shown to have benign disease. The systematic use of the triple test in solid breast lumps for the early detection of cancer is recommended as a routine procedure. However, participation of experienced radiologists and pathologists as well as physicians skilled in fine needle puncture is required.
Martelli
G
G
Division of Diagnostic Oncology, Istituto Nazionale Tumori, Milan, Italy.
Pilotti
S
S
Coopmans de Yoldi
G
G
Viganotti
G
G
Fariselli
G
G
Lepera
P
P
Moglia
D
D
D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D010808:Physical Examination