[The surgical treatment of ovarian cancer].
Between 1980 and 1988, 350 women suffering from ovarian cancer stage I-IV were admitted to the Department of Gynaecology and Obstetrics of the University of Graz. 320 patients underwent surgery, 174 of 175 with stage III disease, 95 patients had a pelvic lymphadenectomy and 76 both pelvic and para-aortic lymphadenectomy. During the last 4 years, 75% of all patients with stage III disease underwent lymphadenectomy; in 30% the abdomen could be completely cleared of the disease. Bowel resection was necessary in 29% of these patients. After surgery and adjuvant chemotherapy, actuarial 5-year survival was 80% in stage I, 65% in stage II. and 45% in stage III. Lymph node status and amount of residual tumour were the most important factors affecting survival. After pelvic lymphadenectomy 23% patients of stage III showed no evidence of disease (NED) after 5 years. If there was no residual tumour at primary surgery, survival with NED increased to 62% and to 71% in patients with negative pelvic nodes. The data indicates, that pelvic lymphadenectomy improved the 5-year survival of patients with stage II-IV ovarian cancer.
Burghardt
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E
Geburtshilflich-gynäkologische Univ.-Klinik Graz.
Lahousen
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M
Stettner
H
H
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002277:Carcinoma / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D015996:Survival Rate
Die operative Behandlung des Ovarialkarzinoms.