title: Angioleiomyoma within a histiocytoma.
abstract: We report an angioleiomyoma developed within a cellular histiocytoma on the calf of a 77-year-old man. The lesion consisted of a spherical nodule with two well-defined concentric areas. The outer circular area was a cellular histiocytoma and the inner central area consisted of an angioleiomyoma. Immunoperoxidase investigations for desmin demonstrated positivity in the angio-leiomyoma, whereas the histiocytoma remained negative. Serial sections of the lesion failed to demonstrate a connection between the angioleiomyoma and a normal vein which could have been trapped by the histiocytoma. The angioleiomyoma may have originated from a vessel in the histiocytoma.
authors: Department of Dermatology, San Carlos University Hospital, Madrid, Spain.
authors: L
authors: L
authors: Requena
authors: S
authors: S
authors: Ortiz
authors: M
authors: M
authors: Sánchez
authors: E S
authors: ES
authors: Yus
mesh_terms: D000368:Aged; D003893:Desmin / Q000032:analysis; D003937:Diagnosis, Differential; D005350:Fibroma / Q000098:blood supply / Q000473:pathology*; D006391:Hemangioma / Q000098:blood supply / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007889:Leiomyoma / Q000098:blood supply / Q000473:pathology*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000098:blood supply / Q000473:pathology*; D012878:Skin Neoplasms / Q000098:blood supply / Q000473:pathology*
chemical_list: D003893:Desmin