title: Efficacy of laidlomycin propionate for increasing rate and efficiency of gain by feedlot cattle.
abstract: One thousand twenty steers and heifers were used in six feeding trials to examine the influence of laidlomycin propionate on feedlot performance and to determine the most efficacious dietary concentrations of that ionophore. Cattle were fed diets ranging in energy content from 1.08 to 1.49 Mcal NEg/kg of DM. Laidlomycin propionate improved rate of gain and feed conversion in both steers and heifers. Improvements in performance were not evident when laidlomycin propionate was fed at only 3 mg/kg. However, both average daily gain and feed conversion were improved by laidlomycin propionate within the range of 6 to 12 mg/kg of DM (P less than .001). Feed consumption was not substantially affected by inclusion of laidlomycin propionate in the diet. Improvements in ADG and feed conversion were greater on lower-energy diets than on higher-energy diets, but both these performance characteristics were improved regardless of the type of diet fed. Average daily gain was maximized with laidlomycin propionate at 6 mg/kg, whereas improvements in feed conversion were sustained through 12 mg/kg. Carcasses of cattle fed diets containing 6 to 12 mg/kg of laidlomycin propionate weighed 7.3 kg more (P less than .001) than carcasses of cattle fed the control diets. Yield grade and quality grade were not affected by laidlomycin propionate (P greater than .05).
authors: Syntex Research, Palo Alto, CA 94304.
authors: H R
authors: HR
authors: Spires
authors: A
authors: A
authors: Olmsted
authors: L L
authors: LL
authors: Berger
authors: J P
authors: JP
authors: Fontenot
authors: D R
authors: DR
authors: Gill
authors: J G
authors: JG
authors: Riley
authors: M I
authors: MI
authors: Wray
authors: R A
authors: RA
authors: Zinn
mesh_terms: D000821:Animal Feed; D000818:Animals; D002417:Cattle / Q000254:growth & development* / Q000378:metabolism; D004063:Digestion / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004435:Eating / Q000187:drug effects; D002149:Energy Intake; D005260:Female; D008297:Male; D008985:Monensin / Q000031:analogs & derivatives* / Q000494:pharmacology; D015430:Weight Gain / Q000187:drug effects*
chemical_list: D008985:Monensin; C010208:laidlomycin