title: Selective photoreceptor cell loss in hypoxic ischemia.
abstract: We studied the histopathologic changes in the brain and eye of a 5 1/2-month-old infant who suffered a profound hypotensive episode three days antemortem. Nuclear pyknosis and other histologic changes characteristic of ischemic cell necrosis were found throughout the brain and in the retina's photoreceptor-cell layer. These findings suggest that hypoxic ischemia may produce preferential damage to the photoreceptor-cell layer.
authors: Department of Ophthalmology, School of Medicine, University of North Carolina, Chapel Hill 27599-7040.
authors: R E
authors: RE
authors: Holman
authors: R L
authors: RL
authors: Peiffer
authors: T W
authors: TW
authors: Bouldin
authors: B S
authors: BS
authors: Grimson
mesh_terms: D001344:Autopsy; D001921:Brain / Q000473:pathology; D002545:Brain Ischemia / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D010786:Photoreceptor Cells / Q000648:ultrastructure*; D012171:Retinal Vessels / Q000648:ultrastructure*; D014057:Tomography, X-Ray Computed