title: Cytogeneticity of quinalphos and methyl parathion in human peripheral lymphocytes.
abstract: 1. Four different concentrations of quinalphos and methyl parathion were tested on human peripheral lymphocytes over different time periods, for the analysis of chromosomal aberrations and sister chromatid exchanges (SCEs). 2. A significant increase in chromosomal aberrations was observed when cells were treated with quinalphos for 48 and 72 h and a significant increase in SCEs was observed at all the concentrations and over all the time periods. 3. Methyl-parathion did not induce chromosomal aberrations but it did induce SCEs significantly over all time periods.
authors: Institute of Genetics, Hospital for Genetic Diseases, Hyderabad, India.
authors: D S
authors: DS
authors: Rupa
authors: P P
authors: PP
authors: Reddy
authors: O S
authors: OS
authors: Reddi
mesh_terms: D002478:Cells, Cultured / Q000187:drug effects; D002869:Chromosome Aberrations / Q000235:genetics*; D006801:Humans; D007306:Insecticides / Q000633:toxicity*; D008214:Lymphocytes / Q000187:drug effects*; D008677:Metaphase; D008743:Methyl Parathion / Q000633:toxicity*; D009946:Organothiophosphorus Compounds / Q000633:toxicity*; D012854:Sister Chromatid Exchange / Q000187:drug effects* / Q000235:genetics; D013997:Time Factors
chemical_list: D007306:Insecticides; D009946:Organothiophosphorus Compounds; C009145:quinalphos; D008743:Methyl Parathion