title: Cushing's syndrome: new variants and association with empty sella syndrome.
abstract: In this article we propose a review of the literature on clinical variants of Cushing's syndrome (CS) and personal observations on one of these variants. Clinical variants of CS are: (1) tumors of the intermediate pituitary lobe; (2) hypothalamic Cushing's with pituitary hyperplasia; (3) cyclic CS; (4) primitive nodular adrenal dysplasia; (5) pre-Cushing's syndrome; (6) association of CS and empty sella. The personal observations relate to the association of CS and empty sella. This syndrome consists of: (a) inappropriate cortisol secretion of pituitary origin; this alteration is less pronounced in comparison with other patients affected by Cushing's disease; (b) marked hirsutism; (c) slight hyperprolactinemia or augmented PRL response after metoclopramide; (d) elevated DHEAS levels.
authors: Institute of Endocrinology, Catholic University School of Medicine, Rome, Italy.
authors: A
authors: A
authors: Mancini
authors: F
authors: F
authors: Calabrò
authors: G
authors: G
authors: Lagonigro
authors: A
authors: A
authors: Saporosi
authors: C
authors: C
authors: Colosimo
authors: C
authors: C
authors: Anile
authors: G
authors: G
authors: Maira
authors: L
authors: L
authors: De Marinis
mesh_terms: D000293:Adolescent; D000328:Adult; D003480:Cushing Syndrome / Q000150:complications / Q000175:diagnosis*; D004652:Empty Sella Syndrome / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008875:Middle Aged