Physiological values of cysteine and metalloproteinase activities in chorionic villi.
Lysosomal cysteine proteinases (cathepsin H, B + L) and metalloproteinase (MMP7-ase) activities were measured from early gestational period (6-12 weeks) in frozen, non-cultivated chorionic villi. The mean activity of cathepsin H was 50.99 mU/mg protein, of cathepsin B + L, 71.16 mU/mg protein, and of MMP7-ase, 16.16 mU/mg protein. The MMP7-ase enzyme activities showed a correlation with gestational age. There was a significant correlation between the activities of cathepsin H and MMP7-ase.
László
A
A
Department of Pediatrics, A. Szent-Györgyi University Medical School, Szeged, Hungary.
Sohár
I
I
Falkay
G
G
Kovács
A
A
Halmos
V
V
Szabó
J
J
D002403:Cathepsins / Q000032:analysis*; D002824:Chorionic Villi / Q000201:enzymology*; D003546:Cysteine Endopeptidases / Q000032:analysis; D005260:Female; D005865:Gestational Age; D006801:Humans; D008666:Metalloendopeptidases / Q000032:analysis*; D011247:Pregnancy
D002403:Cathepsins; D003546:Cysteine Endopeptidases; D008666:Metalloendopeptidases