[The immunobiological properties of the antigenic preparations obtained from a vaccinal strain of Klebsiella pneumoniae 204 grown in media of differing compositions].
In the technology of the cultivation of K. pneumoniae vaccine strain 204 with a view to obtaining biomass for the production of antigenic preparations the traditionally used culture medium with full nutritional value has been replaced by the alternative variant of synthetic medium. The specific physiological and morphological features of this strain grown in synthetic culture medium have been studied and described. Irrespective of the composition of the culture media used for cultivation, the antigenic preparations have been shown to have no difference in their chemical composition, immunogenic and toxic properties.
Miriasova
L V
LV
Basnak'ian
I A
IA
Egorova
N B
NB
Kurbatova
E A
EA
Reshilov
L N
LN
Krylova
A Iu
AIu
Efimtseva
O V
OV
Shagam
N L
NL
Salov
V F
VF
D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology* / Q000302:isolation & purification / Q000633:toxicity; D001428:Bacterial Vaccines / Q000276:immunology* / Q000302:isolation & purification / Q000633:toxicity; D003470:Culture Media; D007114:Immunization; D007711:Klebsiella pneumoniae / Q000254:growth & development / Q000276:immunology* / Q000648:ultrastructure; D007928:Lethal Dose 50; D051379:Mice; D008854:Microscopy, Electron
D000942:Antigens, Bacterial; D001428:Bacterial Vaccines; D003470:Culture Media
Immunobiologicheskie svoĭstva antigennykh preparatov, poluchennykh iz vaktsinnogo shtamma Klebsiella pneumoniae 204, vyrashchennogo v sredakh razlichnogo sostava.