[Isolated prolongation of the PTT: 2-year retrospective study].
The hemorrhagic risk associated with isolated prolongation of the PTT has been evaluated in a 2-year retrospective study. Of the 60 cases thus found, a hemorrhagic risk was present in 15 patients of whom 7 had hemophilia A, 5 von Willebrand's disease and 3 factor XI deficiency. Among the other etiologies not associated with a bleeding tendency, there were 31 proved or suspected cases with inhibitors of the PTT, most of whom were children, 2 factor XII deficiencies, 2 prekallikrein deficiencies and 4 contact phase activations. Isolated prolongation of the PTT is therefore without specificity and needs further investigation of hemostasis to determine the associated hemorrhagic risk.
Michel-Reymond
G
G
Département de médecine interne, Centre hospitalier universitaire vaudois, Lausanne.
Knecht
H
H
Hauert
J
J
Bachmann
F
F
D005173:Factor XI Deficiency / Q000097:blood; D006402:Hematologic Diseases / Q000097:blood*; D006467:Hemophilia A / Q000097:blood; D006470:Hemorrhage / Q000097:blood*; D006801:Humans; D011517:Prothrombin Time; D012189:Retrospective Studies; D012307:Risk Factors; D014842:von Willebrand Diseases / Q000097:blood
Allongement isolé du PTT: étude rétrospective sur 2 ans.