title: [The clinical efficacy of and tolerance for lariam (mefloquine) in tropical malaria in the south of the Socialist Republic of Vietnam].
abstract: The study was performed in the area of distribution of tropical malaria resistant to 4-aminoquinolines (Vietnam) on 30 patients receiving lariam (mefloquine). The results were compared to the standard therapy with quinine and fansidar. They indicate a high efficacy of and a good tolerance to the drug tested. The use of lariam leads to a more rapid (as compared to the standard treatment) elimination of parasitemia and complete eradication of the disease relapses. The findings make it possible to recommend lariam for the prevention and treatment of tropical malaria.
authors: A M
authors: AM
authors: Shcherbakov
authors: T L
authors: TL
authors: Nguyen
authors: K A
authors: KA
authors: Chin
authors: K T
authors: KT
authors: Chan
authors: S A
authors: SA
authors: Rabinovich
authors: V D
authors: VD
authors: Nguyen
authors: V F
authors: VF
authors: Chan
authors: T L
authors: TL
authors: Nguyen
authors: T T
authors: TT
authors: Vu
authors: H
authors: H
authors: Padelt
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use; D004338:Drug Combinations; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D008288:Malaria / Q000188:drug therapy*; D008297:Male; D015767:Mefloquine / Q000627:therapeutic use*; D008875:Middle Aged; D010963:Plasmodium falciparum; D011739:Pyrimethamine / Q000627:therapeutic use; D011803:Quinine / Q000627:therapeutic use; D013413:Sulfadoxine / Q000627:therapeutic use; D014744:Vietnam
chemical_list: D000962:Antimalarials; D004338:Drug Combinations; C001205:fanasil, pyrimethamine drug combination; D013413:Sulfadoxine; D011803:Quinine; D015767:Mefloquine; D011739:Pyrimethamine
vernacular_title: Klinicheskaia éffektivnost' i perenosimost' lariama (meflokhina) pri tropicheskoĭ maliarii na iuge SRV.