Results of fractionated TBI prior to bone marrow transplantation in standard risk leukaemia at Marseille.
One hundred and six patients with standard risk leukaemia were given fractionated TBI prior to allogeneic (72 cases, 27 of whom were T-depleted) or autologous (34 cases) bone marrow transplantation (BMT). Disease free survival at 5 years is 68% for allogeneic non T-depleted BMT and 33% for T-depleted BMT. Deaths are related to relapse, GVHD, infections, pneumonitis, encephalitis, VOD, AIDS, rejection.
Resbeut
M
M
Institut J. Paoli-I.Calmettes, Marseille, France.
Altschuler
C
C
Blaise
D
D
Maraninchi
D
D
Stoppa
A M
AM
Guillet
J P
JP
Carcassonne
Y
Y
D000293:Adolescent; D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects; D002985:Clinical Protocols; D003131:Combined Modality Therapy; D006801:Humans; D007938:Leukemia / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery; D008212:Lymphocyte Depletion; D009364:Neoplasm Recurrence, Local; D011879:Radiotherapy Dosage; D013601:T-Lymphocytes; D014916:Whole-Body Irradiation / Q000379:methods*