title: Sex chromosome configurations in pachytene spermatocytes of an XYY mouse.
abstract: Karyotypic investigation of a phenotypically normal but sterile male mouse showed the presence of an XYY sex chromosome constitution. The synaptic behaviour of the three sex chromosomes was examined in 65 pachytene cells. The sex chromosomes formed a variety of synaptic configurations: an XYY trivalent (40%); an XY bivalent and Y univalent (38.5%); an X univalent and YY bivalent (13.8%); or X, Y, Y univalence (7.7%). There was considerable variation in the extent of synapsis and some of the associations clearly involved nonhomologous pairing. These observations have been compared with previously published information on chromosome configurations at metaphase I from other XYY males.
authors: M.R.C. Radiobiology Unit, Chilton, Didcot, Oxon, U.K.
authors: C
authors: C
authors: Tease
mesh_terms: D000818:Animals; D005260:Female; D007621:Karyotyping; D008297:Male; D008540:Meiosis; D051379:Mice; D013090:Spermatocytes / Q000378:metabolism*; D014960:X Chromosome / Q000648:ultrastructure*; D014997:XYY Karyotype / Q000235:genetics*; D014998:Y Chromosome / Q000648:ultrastructure*