Mutagenesis and micronutrients relationship.
Several micronutrients have been reported to be mutagenic or co-mutagenic in certain in vitro testing systems. However, micronutrients have not been shown to be mutagenic or co-mutagenic in vivo, or at physiological concentrations in vitro. Most of the mutagenic or co-mutagenic effects of micronutrients observed in vitro can be attributed to their involvement in the generation of oxygen radicals. Many micronutrients have been shown to possess anti-mutagenic or co-antimutagenic activity in vitro and in vivo. This property of micronutrients appears to be linked to their specific and interrelated biochemical functions.
Chow
C K
CK
Department of Nutrition and Food Science, University of Kentucky, Lexington 40506.
D000818:Animals; D000975:Antioxidants / Q000009:adverse effects*; D002478:Cells, Cultured; D009153:Mutagens; D014131:Trace Elements / Q000009:adverse effects*; D014815:Vitamins / Q000009:adverse effects*
D000975:Antioxidants; D009153:Mutagens; D014131:Trace Elements; D014815:Vitamins