title: Blood viscosity and optimal hematocrit in narrow tubes.
abstract: Blood viscosity in normal adults was measured in glass tubes with diameters of 50, 100 and 500 microns for a wide range of adjusted feed hematocrits (15-70%). Blood viscosity decreased at each of the adjusted feed hematocrits when going from a 500-micron tube to a 50-micron tube. The viscosity reduction increased with increasing hematocrit. The steepness in the hematocrit-viscosity curves decreased with decreasing tube diameter. Erythrocyte transport efficiency (hematocrit/blood viscosity) was calculated to estimate the optimal hematocrit for oxygen transport. Optimal hematocrit averaged 38% in 500-micron tubes, 44% in 100-micron tubes and 51% in 50-micron tubes. Our results suggest that the strong Fåhraeus-Lindqvist effect at high hematocrits may help to maintain oxygen transport in polycythemic patients as long as the driving pressure is sufficient.
authors: Department of Pediatrics, University of Heidelberg, Federal Republic of Germany.
authors: A A
authors: AA
authors: Stadler
authors: E P
authors: EP
authors: Zilow
authors: O
authors: O
authors: Linderkamp
mesh_terms: D000328:Adult; D001809:Blood Viscosity / Q000502:physiology*; D006400:Hematocrit; D006801:Humans; D008954:Models, Biological; D010100:Oxygen / Q000502:physiology; D011086:Polycythemia / Q000097:blood
chemical_list: D010100:Oxygen