Respiratory muscle function in cystic fibrosis.
Maximal static expiratory and inspiratory mouth pressures (PEmax and PImax) and quadriceps femoris muscle strength were measured in 25 patients aged 16-28 years with cystic fibrosis (mean FEV1 46% predicted). Mean (SD) PEmax was 64% (18%) predicted (below 75% predicted in 16 of the 25 patients), and PImax was 64% (24%) predicted (below 75% predicted in 14 patients). Quadriceps muscle strength was 68% (20%) predicted (below 75% predicted in 17 patients). The relatively small reduction in respiratory muscle strength in these patients was unlikely to have contributed appreciably to their respiratory problems.
Mier
A
A
Brompton Hospital, London.
Redington
A
A
Brophy
C
C
Hodson
M
M
Green
M
M
D000293:Adolescent; D000328:Adult; D000399:Air Pressure; D003550:Cystic Fibrosis / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D009119:Muscle Contraction / Q000502:physiology; D012119:Respiration / Q000502:physiology; D012132:Respiratory Muscles / Q000503:physiopathology*; D013848:Thigh / Q000503:physiopathology