title: Introduction: B27-associated diseases.
abstract: As an introduction, a hypothesis for the causation of ankylosing spondylitis, reactive arthritis, psoriatic arthritis, and rheumatoid arthritis is outlined. It comprises ten basic mechanisms. With that hypothesis as a background, a further ten issues based on clinical evidence are presented for discussion. Finally, four questions are presented on behalf of the clinicians.
authors: Department of Therapeutics, Charing Cross and Westminster Medical School, London, U.K.
authors: D A
authors: DA
authors: Brewerton
mesh_terms: D001170:Arthritis, Infectious / Q000276:immunology; D015535:Arthritis, Psoriatic / Q000276:immunology; D001172:Arthritis, Rheumatoid / Q000276:immunology; D015796:HLA-B27 Antigen / Q000378:metabolism*; D006801:Humans; D013167:Spondylitis, Ankylosing / Q000276:immunology
chemical_list: D015796:HLA-B27 Antigen