title: Tumefactive fibroinflammatory lesions of the head and neck.
abstract: The term 'tumefactive fibroinflammatory lesion' has been used to describe a fibrosclerosing disorder which has a locally destructive nature but is characterized by a benign histological appearance. We report five patients, over a five year period, with such a lesion. The clinical behaviour and surgical findings suggest the lesion to be an invasive malignancy. However, the histological appearance of an admixture of chronic inflammatory cells and fibrosis is consistent with a benign condition. We recommend surgical excision of the lesion as the mainstay of treatment; other studies report the use of steroids and radiotherapy.
authors: Department of Otolaryngology, Leicester Royal Infirmary.
authors: A J
authors: AJ
authors: Prichard
authors: P
authors: P
authors: Colloby
authors: R P
authors: RP
authors: Barton
authors: J M
authors: JM
authors: Heaton
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005355:Fibrosis; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007249:Inflammation; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed