Chronic cough due to angiotensin-converting enzyme inhibitors.
The ACE-inhibiting drugs enalapril and captopril may result in a chronic and sometimes severe cough for which no pathologic cause can be found. Drug-induced cough should therefore be considered in any symptomatic patient taking these medications. In such cases, prompt withdrawal of the drug and substitution of a non-ACE inhibitor is curative and conserves the time and resources of the patient and the physician by avoiding unnecessary diagnostic and therapeutic measures.
Nuss
D W
DW
Department of Otolaryngology, Louisiana State University Medical Center, New Orleans.
Lyons
G D
GD
Joseph
J J
JJ
D000368:Aged; D002908:Chronic Disease; D003371:Cough / Q000139:chemically induced* / Q000628:therapy; D004305:Dose-Response Relationship, Drug; D004656:Enalapril / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged
D004656:Enalapril