Eosinophilic myositis an expression of L-tryptophan toxicity?
Eosinophilia-myalgia syndrome possibly due to L-tryptophan is a new clinical entity that has been recently reported. We describe the clinical presentation of eosinophilia, eosinophilic pustular folliculitis, myalgia, and eosinophilic myositis, that led to respiratory failure in a young man taking an L-tryptophan containing compound.
Estrada
C A
CA
Department of Medicine and Neurology, Henry Ford Hospital, Detroit, MI 48202.
Harrington
D W
DW
Glasberg
M R
MR
D000328:Adult; D001706:Biopsy; D004802:Eosinophilia / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008297:Male; D009132:Muscles / Q000473:pathology; D009220:Myositis / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D012131:Respiratory Insufficiency / Q000139:chemically induced; D013256:Steroids / Q000627:therapeutic use; D014364:Tryptophan / Q000009:adverse effects*
D013256:Steroids; D014364:Tryptophan