Leiomyosarcoma arising in a lipoleiomyoma.
A leiomyosarcoma arising in a uterine lipoleiomyoma is described in a 70-year-old woman. The tumor measured 11 cm and was located in the corpus uteri. It was composed of a mixture of firm, pale tan, whorled tissue and soft, white or hemorrhagic areas. Histologically, the firm tissue was a mixture of bland smooth muscle, fat and fibrous tissue, whereas the soft areas showed a malignant spindle cell tumor with smooth muscle differentiation. Pure sarcoma similar to the malignant portion of the lipoleiomyoma had metastasized to the vaginal wall.
Scurry
J
J
Department of Anatomical Pathology, Monash Medical Centre, Clayton, Australia.
Hack
M
M
D000368:Aged; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000473:pathology* / Q000648:ultrastructure; D007890:Leiomyosarcoma / Q000473:pathology* / Q000648:ultrastructure; D008067:Lipoma / Q000473:pathology* / Q000648:ultrastructure; D009130:Muscle, Smooth / Q000473:pathology; D009378:Neoplasms, Multiple Primary