title: [The effect of the duration of a weight reduction regimen on the hormonal, metabolic and cardiovascular response].
abstract: The rapid weight decrease at the beginning of strict slimming regimens leads often to an inconsiderate shortening of these cures. Our long-termed experience with a slimming regimen lasting 13 days and based on diet (3.7 MJ) and 4 hours of supervised exercise of low to moderate intensity was omitted by the organizers. They shortened the cure to 8 days. We checked therefore a group of obese women on the first, eighth and twelfth day in the course of this regimen. A statistically significant decrease of serum insulin, growth hormone, triiodothyronine and cholesterol was observed on the twelfth day. These trends were not significant on the eighth day. On the other hand, the step-test has shown on the eighth day a reduction of the heart rate during recovery. Nevertheless, a higher level of significance was obtained after a cure of 12 days. No significant response to the regimen was obtained in the case of blood glucose, thyroxine, cortisol, uric acid, AST and ALT. The advantages of the 12 day regimen were discussed--especially the decrease of insulinemia, because hyperinsulinemia is responsible for several complications of obesity. The importance of the decrease of cholesterolemia and the modification of heart rate after a load was also stressed. These favourable effects should not be depreciated by a smaller weight decrease on the second week due to an enhanced synthesis of proteins, stimulated by exercise and supported by a decrease of T3 which brings a protection against energy defficiency.
authors: III. interní klinika 1. lékarské fakulty Univerzity Karlovy, Praha.
authors: J
authors: J
authors: Sonka
authors: Z
authors: Z
authors: Límanová
authors: I
authors: I
authors: Neffeová
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D002784:Cholesterol / Q000032:analysis; D005080:Exercise Test; D005260:Female; D006339:Heart Rate; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007328:Insulin / Q000097:blood; D009765:Obesity / Q000097:blood / Q000503:physiopathology* / Q000628:therapy; D013963:Thyroid Hormones / Q000032:analysis; D013997:Time Factors; D015431:Weight Loss
chemical_list: D001786:Blood Glucose; D007328:Insulin; D013963:Thyroid Hormones; D002784:Cholesterol; D006854:Hydrocortisone
vernacular_title: Vliv délky kombinovaného redukcního rezimu na hormonální, metabolickou a kardiovaskulární odezvu.