title: Type I hypersensitivity to rubber.
abstract: Seven patients with type I hypersensitivity reactions to rubber are reported. Radioallergosorbent testing with crude latex antigen was positive in 6/7 patients. Five patients had coexisting spina bifida, and all had undergone surgery before the development of rubber allergy. Rubber allergy is a new phenomenon that should be in the differential diagnosis of idiopathic anaphylaxis and urticaria.
authors: Department of Allergy and Immunology, (Spina Bifida Program), Children's National Medical Center, Washington, DC.
authors: J E
authors: JE
authors: Slater
authors: L A
authors: LA
authors: Mostello
authors: C
authors: C
authors: Shaer
authors: R W
authors: RW
authors: Honsinger
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000209:etiology*; D007073:Immunoglobulin E / Q000276:immunology; D008297:Male; D011852:Radioallergosorbent Test; D012408:Rubber / Q000009:adverse effects*; D016135:Spinal Dysraphism / Q000150:complications
chemical_list: D007073:Immunoglobulin E; D012408:Rubber