Hepatoprotective effects of astraglus root.
Oral administration of an ethanol extract of the root of Astragalus membranaceus alleviated liver injury induced by stilbenemidine. Pre-administration in mice reduced elevated SGPT levels and subacute toxicity of stilbenemidine, decreased pentobarbital-induced loss of righting reflex and protected hepatic cells from pathological changes.
Zhang
Z L
ZL
Tianjin Institute of Pharmaceutical Research, State Pharmaceutical Administration of China.
Wen
Q Z
QZ
Liu
C X
CX
D000410:Alanine Transaminase / Q000378:metabolism; D000818:Animals; D027885:Astragalus propinquus; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D008099:Liver / Q000187:drug effects / Q000473:pathology; D008107:Liver Diseases / Q000201:enzymology / Q000517:prevention & control*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009336:Necrosis; D010424:Pentobarbital / Q000494:pharmacology; D012890:Sleep / Q000187:drug effects; D013267:Stilbenes / Q000633:toxicity
D004365:Drugs, Chinese Herbal; D013267:Stilbenes; C066598:stilbenemide; D000410:Alanine Transaminase; D010424:Pentobarbital