[Mathematical approach to the evaluation of prognostic factors in chronic myeloid leukemia].
The incidence rate of each out of 25 clinico-laboratory signs was analyzed mathematically in 87 patients with chronic myeloid leukemia, the estimation of the signs was conducted in relation to the aggressiveness of the leukemic process. Prognostically unfavourable signs have been revealed, on their basis groups of "risk" could be formed among the patients who need individually selected chemotherapy. The combination of unfavourable factors produces a noticeable effect on the mean lifetime and the disease prognosis in patients with an aggressive course of chronic myeloid leukemia.
Shardkov
V I
VI
Dem'ianova
V T
VT
D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive; D008432:Mathematical Computing; D011379:Prognosis; D012307:Risk Factors
Matematicheskiĭ podkhod k otsenke prognosticheskikh faktorov pri khronickeskom mieloleĭkoze.