Management of severe hemolytic disease with ultrasound-guided intravascular fetal transfusions.
Between January 1987 and March 1989, 22 fetuses with severe hemolytic disease were treated with 64 ultrasound-guided intrauterine intravascular transfusions. Eighteen infants survived and are doing well. In 12 fetuses, hydropic changes were present at the first transfusion; 9 of these survived. In 8 of the 10 fetuses with a gestational age less than 26 weeks, intrauterine treatment was successful.
Kanhai
H H
HH
Department of Obstetrics, University of Leiden, The Netherlands.
Bennebroek Gravenhorst
J
J
van Kamp
I L
IL
Meerman
R H
RH
Brand
A
A
Dohmen-Feld
M W
MW
Ruys
J H
JH
D001805:Blood Transfusion, Intrauterine / Q000379:methods*; D004899:Erythroblastosis, Fetal / Q000628:therapy*; D005260:Female; D005865:Gestational Age; D006400:Hematocrit; D006801:Humans; D015160:Hydrops Fetalis / Q000628:therapy; D007231:Infant, Newborn; D011247:Pregnancy; D014463:Ultrasonography