title: Hemolysis of rabbit erythrocytes induced by cigarette smoke.
abstract: Cigarette smoke has been found to induce the hemolysis of rabbit erythrocytes. The particulate phase had more profound effect than the gas phase. Neither free radical scavengers such as ascorbic acid, uric acid and water-soluble vitamin E analogue nor antioxidant enzymes such as catalase and superoxide dismutase suppressed the cigarette smoke-induced hemolysis, suggesting that free radicals, hydrogen peroxide, and superoxide were not the active species.
authors: Department of Reaction Chemistry, Faculty of Engineering, University of Tokyo, Japan.
authors: S
authors: S
authors: Minamisawa
authors: E
authors: E
authors: Komuro
authors: E
authors: E
authors: Niki
mesh_terms: D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology; D001219:Aspartate Aminotransferases / Q000378:metabolism; D002374:Catalase / Q000494:pharmacology; D004912:Erythrocytes / Q000187:drug effects; D005609:Free Radicals; D006454:Hemoglobins / Q000378:metabolism; D006461:Hemolysis; D010947:Plants, Toxic; D011188:Potassium / Q000378:metabolism; D011817:Rabbits; D012906:Smoke / Q000009:adverse effects*; D013482:Superoxide Dismutase / Q000494:pharmacology; D014026:Nicotiana; D014527:Uric Acid / Q000494:pharmacology; D014810:Vitamin E / Q000494:pharmacology
chemical_list: D005609:Free Radicals; D006454:Hemoglobins; D012906:Smoke; D014810:Vitamin E; D014527:Uric Acid; D002374:Catalase; D013482:Superoxide Dismutase; D001219:Aspartate Aminotransferases; D001205:Ascorbic Acid; D011188:Potassium