title: [Respiratory distress after endotracheal insufflation of baby powder in dogs].
abstract: The cause of delayed respiratory distress after endotracheal insufflation of baby powder was investigated in dogs. Ten dogs were divided into 2 groups. In the insufflation group (n = 6), baby powder 1g.kg-1 was insufflated through an endotracheal tube under controlled mechanical ventilation. In the control group (n = 4), artificial ventilation was continued for 36 hours without insufflation of baby powder. PaO2 in the insufflation group fell until 1 hour, and then improved until 12 hours after the insufflation. But PaO2 fell again after 12 hours, and all dogs died by 36 hours after the insufflation. Pathological examination of the lungs of the insufflation group revealed gram-negative bacillus pneumonia, but no pneumonia occurred in the control group. Gram-negative bacillus was not detected in the baby powder, but Acinetobacter calcoaceticus was found from the tracheal swabs of the dog. Therefore, delayed respiratory distress was thought to have been caused by A. calcoaceticus pneumonia. It was concluded that A. calcoaceticus, which comprises a part of the indigenous flora of the respiratory tract of the dog, finally caused pneumonia and death of the dogs after baby powder insufflation because baby powder had damaged the lung's defence of bacterial clearance.
authors: Department of Anesthesiology, Yokohama City University School of Medicine.
authors: M
authors: M
authors: Sumitomo
mesh_terms: D000151:Acinetobacter Infections / Q000209:etiology*; D000280:Administration, Inhalation; D000818:Animals; D004285:Dogs; D007442:Intubation, Intratracheal; D011014:Pneumonia / Q000209:etiology*; D012131:Respiratory Insufficiency / Q000209:etiology*; D013627:Talc / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D013627:Talc