Comments on two recent deconvolution methods.
In a recent paper Vajda et al. presented a deconvolution method based on the assumptions that the response of a system and the input function to a system are described by first-order linear processes. The method is similar to one proposed by Veng-Pedersen, and obtains similar results. In this article a simpler, not new, and now generally available method for this special use is considered to point out potential risks associated with all three deconvolution methods.
Verotta
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Department of Laboratory Medicine, School of Medicine, University of California, San Francisco 94143.
D002927:Cimetidine / Q000493:pharmacokinetics; D003627:Data Interpretation, Statistical; D016014:Linear Models; D008432:Mathematical Computing; D008722:Methods; D010599:Pharmacokinetics
D002927:Cimetidine