title: Synthetic laminaria tent for cervical ripening.
abstract: The efficacy and safety of a synthetic laminaria tent (Lamicel; Cabot) in ripening the cervix before induction of labour was compared with prostaglandin E2 (PGE2) oral tablets used intravaginally. Eighty patients were randomly assigned to use of the laminaria tent (N = 40) or PGE2 (N = 40). There were an equal number of primigravidas and multigravidas in each group. The only significant difference between the groups was the higher frequency of uterine hypertonicity (29 v. 5 : PGE2 v. tent) and consequent fetal distress (5 v. 1 : PGE2 v. tent) in the PGE2 group. However, the duration of labour was shorter in the PGE2 group than in the tent group (10, 14 h v. 11,61 h). These findings indicate that the synthetic laminaria tent is the preferred agent for cervical ripening in high-risk pregnancies and in developing countries.
authors: Department of Obstetrics and Gynaecology, University of Natal, Durban.
authors: J S
authors: JS
authors: Bagratee
authors: J
authors: J
authors: Moodley
mesh_terms: D000282:Administration, Intravaginal; D000293:Adolescent; D000328:Adult; D002584:Cervix Uteri / Q000502:physiology*; D005260:Female; D006801:Humans; D007751:Labor, Induced / Q000379:methods*; D007795:Laminaria; D011247:Pregnancy; D011458:Prostaglandins E / Q000008:administration & dosage; D011897:Random Allocation
chemical_list: D011458:Prostaglandins E