title: Effects of nifedipine on diastolic function in hypertensive patients--an echocardiographic study.
abstract: This study was undertaken to observe the changes in heart function and evaluate the effects of nifedipine on diastolic function in 70 patients with uncomplicated hypertension by M-mode and Doppler echocardiography. The results showed that diastolic abnormalities in hypertensive patients may precede systolic dysfunction and that nifedipine can improve diastolic function. It is easy and quick to estimate the diastolic function by measuring the EF slope, EA and EPSS, especially the E wave velocities. This method proved to be applicable to clinical practice.
authors: Department of Cardiology, Tongji Hospital, Tongji Medical University, Wuhan.
authors: Z M
authors: ZM
authors: Hu
authors: S Q
authors: SQ
authors: Xiang
authors: S Y
authors: SY
authors: Gao
mesh_terms: D000328:Adult; D000368:Aged; D003971:Diastole / Q000502:physiology; D004452:Echocardiography; D015150:Echocardiography, Doppler; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000494:pharmacology / Q000627:therapeutic use*; D016277:Ventricular Function, Left / Q000187:drug effects*
chemical_list: D009543:Nifedipine