Bilateral visual loss with eosinophilic infiltration in the bone marrow and the retina.
A young patient is described who presented with sudden visual loss in the left eye quickly followed by proliferative retinopathy with retinal detachment and thrombotic glaucoma. He developed similar initial symptoms in the right eye but has now made a complete recovery in that eye on systemic steroids, oral acyclovir, cyclosporin A and colchicine. Pathological examination of the left eye revealed inflammation in the ciliary body, retina and choroid with prominent eosinophils. The nature of the initial insult and the possible role of the eosinophils are discussed.
Woon
H W
HW
Medical Eye Unit, St. Thomas' Hospital, London, England.
Graham
E M
EM
D000328:Adult; D001766:Blindness / Q000209:etiology* / Q000473:pathology; D001853:Bone Marrow / Q000473:pathology*; D004804:Eosinophils; D005128:Eye Diseases / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D015353:Eye Enucleation; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D005901:Glaucoma / Q000150:complications / Q000209:etiology; D006801:Humans; D008297:Male; D012160:Retina / Q000473:pathology*; D012163:Retinal Detachment / Q000150:complications / Q000209:etiology / Q000473:pathology; D012164:Retinal Diseases / Q000150:complications / Q000209:etiology / Q000473:pathology