title: Drugs-of-abuse testing. Screening and confirmation.
abstract: It is essential to understand that any rapid urine drugs-of-abuse screening test should be confirmed by an equally sensitive and more specific test. In this regard, the confirmation procedure chosen should provide the most accurate and unequivocal results possible. Confirmation techniques other than GC/MS may be adequate for certain drugs of abuse, but GC/MS is generally accepted as the most rigorous confirmation technique for most drugs of abuse. It provides the best confirmatory information when performed appropriately. Consumers should be aware of the limitations of screening tests and the need for more specific confirmatory testing. Each drug-of-abuse testing claim must be supported by appropriate data. Labeling instructions and other pertinent information must be accurate. Labeling for drug-testing devices must provide adequate information about the intended use and expected performance, in addition to instructions for use, known limitations, and indications of the quality of performance.
authors: Division of Clinical Laboratory Devices, US Food and Drug Administration, Rockville, Maryland.
authors: K
authors: K
authors: Aziz
mesh_terms: D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D013287:Illicit Drugs / Q000032:analysis*; D011786:Quality Control; D013048:Specimen Handling
chemical_list: D013287:Illicit Drugs