[The sociomedical efficacy of the enzyme therapy of gonorrhea patients].
The study has involved 3702 male patients with gonorrhea. Of these 62 percent were fresh cases, 38 percent chronic ones; there were 218 patients (5.9 percent) with recurrences, of these 63.3 percent with new relapses and 36.7 percent with chronic ones. 85.3 percent of patients developed monorelapses. The recurrences were equally frequent after antibiotic therapy (50.2 percent) and after combined treatment (49.8 percent). Proteolytic enzymes (chymotrypsin, trapsin 5 mg twice daily with a 12 hrs interval) in combination with an antibiotic were administered to 242 patients with gonorrhea complicated by epididymo-orchitis and with gonorrhea relapses. Etiologic cure was achieved in all of them; postgonorrheal conditions were recorded in 6-7 percent and depended on the antibiotic administered; in reference patients recurrences were recorded in 4.2-6.5 percent of cases, postgonorrheal conditions in 14-21.4 percent of cases. Enzymic therapy helped reduce the length of inpatient therapy of a patient by 5.93 days on an average in cases with orchidoepididymitis and by 14.64 days in gonorrhea relapses, with the economic effect per worker being 131.4 and 307.2 rubles, respectively.
Glozman
V N
VN
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002908:Chronic Disease; D002918:Chymotrypsin / Q000627:therapeutic use*; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D006069:Gonorrhea / Q000188:drug therapy* / Q000191:economics; D006801:Humans; D008297:Male; D012008:Recurrence; D012936:Social Medicine; D014357:Trypsin / Q000627:therapeutic use*
D000900:Anti-Bacterial Agents; D002918:Chymotrypsin; D014357:Trypsin
Mediko-sotsial'naia éffektivnost' énzimoterapii bol'nykh gonoreĭ.