title: Effect of vasectomy on in situ pH in rat testis and epididymis.
abstract: The effect of bilateral vasectomy on in situ pH in seminiferous tubules, initial segments, proximal caput, middle corpus and proximal cauda epididymides of the rat has been studied employing in vivo microelectrode techniques. After bilateral vasectomy of four weeks duration, a significant increase in acidity of luminal fluid in the initial segments of the caput epididymides was observed. By eight weeks post vasectomy, luminal pH in the initial segments was significantly more acid as compared to sham-operated control animals or four weeks vasectomy while, in contrast, luminal pH in the proximal cauda epididymides was significantly more alkaline. The alteration of luminal fluid pH in the initial segments and proximal cauda epididymides after bilateral vasectomy may be the result of impairment of acid-base, as well as water transport pathways.
authors: Department of Internal Medicine, University of Texas Medical Branch, Galveston 77550.
authors: C R
authors: CR
authors: Caflisch
authors: T D
authors: TD
authors: DuBose
mesh_terms: D000818:Animals; D004822:Epididymis / Q000502:physiology*; D006863:Hydrogen-Ion Concentration; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012661:Semen / Q000378:metabolism; D013737:Testis / Q000502:physiology*; D014659:Vasectomy / Q000009:adverse effects*