title: [Achievements in the search for and creation of Soviet anthelmintic agents].
abstract: Basic achievements in the creation of antinematodal, anticestodal and antitrematodal agents are reviewed chronologically. It is shown that the search was performed mainly among the derivatives of benzimidazole, cyclic amidines, diphenylmethane, salicyl anilides, pyrazine isoquinolines, among natural products of avermictines and milbemicines. It is noted that nowadays there is every possibility for the treatment of mass helminthiases in the USSR. However, it has been found that some drugs are associated with a certain risk and therefore the necessity for further search of safe anthelminthic agents has been emphasized.
authors: M N
authors: MN
authors: Lebedeva
authors: F S
authors: FS
authors: Mikhaĭlitsyn
authors: Iu S
authors: IuS
authors: Tsizin
authors: B A
authors: BA
authors: Astaf'ev
mesh_terms: D000871:Anthelmintics / Q000737:chemistry / Q000627:therapeutic use*; D000923:Anticestodal Agents / Q000737:chemistry / Q000627:therapeutic use; D000969:Antinematodal Agents / Q000737:chemistry / Q000627:therapeutic use; D000980:Antiplatyhelmintic Agents / Q000737:chemistry / Q000627:therapeutic use; D004341:Drug Evaluation; D006373:Helminthiasis / Q000188:drug therapy; D006801:Humans; D012106:Research; D014586:USSR
chemical_list: D000871:Anthelmintics; D000923:Anticestodal Agents; D000969:Antinematodal Agents; D000980:Antiplatyhelmintic Agents
vernacular_title: Uspekhi v poiske i sozdanii otechestvennykh protivogel'mintnykh sredstv.