title: Separation of tubular electrical activity in amphibian skeletal muscle through temperature change.
abstract: The effect of temperature on the form of the propagated action potential was investigated in frog skeletal muscle fibres. Increasing the temperature decreased the duration of the initial overshoot but a hump then appeared during a more prominent after-depolarization. Finally, at 28-30 degrees C, the after-depolarization was either noticeably enlarged or entirely absent. This all-or-none failure of tubular conduction suggests that excitation of the tubular membrane takes place through regenerative activity rather than graded electrotonic spread of depolarization. However, it is consistent with a partial electrical isolation of the tubular lumina, possibly through the access resistance proposed in earlier theoretical models for muscle membrane.
authors: Physiological Laboratory, Cambridge.
authors: N
authors: N
authors: Padmanabhan
authors: C L
authors: CL
authors: Huang
mesh_terms: D000200:Action Potentials; D000818:Animals; D004594:Electrophysiology; D009132:Muscles / Q000502:physiology*; D011896:Rana temporaria; D013696:Temperature