[Beta-2-microglobulin expression in oral lichen planus].
In 15 patients suffering from oral lichen planus (OLP), we took biopsies of both involved and noninvolved oral mucosa. The specimens were immunohistochemically studied with regard to the expression of beta-2-microglobulin (beta 2-M). In contrast to noninvolved mucosa, we proved definite beta 2-M expression in keratinocytes from OLP lesions. Our findings agree with the assumption that an autoimmunological process is involved in the pathogenesis of OLP.
Simon
M
M
Dermatologische Universitäts-Klinik Erlangen.
Vigneswaran
N
N
D000328:Adult; D001706:Biopsy; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008010:Lichen Planus / Q000473:pathology*; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology; D013280:Stomatitis / Q000473:pathology*; D001613:beta 2-Microglobulin / Q000032:analysis*
D001613:beta 2-Microglobulin
Beta-2-Mikroglobulin-Expression bei oralem Lichen planus.