Neodymium: YAG laser hysteroscopy in large submucous fibroids.
The preoperative use of a potent, subcutaneously injected gonadotropin-releasing hormone agonist (GnRH-a) was evaluated in a series of 60 women with large submucosal fibroids. Myomectomy by hysteroscopy and Nd:YAG laser was easily performed. In 12 cases, the largest portion of the myoma was not inside the uterine cavity and myomectomy was carried by a two-step hysteroscopy. In women who wished to become pregnant, a pregnancy rate of 66% was achieved. Advantages of preoperative use of a GnRH-a are (1) the significant decrease of the fibroid size, (2) a lower fluid absorption, and (3) the restoration of a normal hemoglobin concentration.
Donnez
J
J
Department of Gynecology, University of Louvain, Brussels, Belgium.
Gillerot
S
S
Bourgonjon
D
D
Clerckx
F
F
Nisolle
M
M
D000328:Adult; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D007987:Gonadotropin-Releasing Hormone / Q000502:physiology; D006801:Humans; D015907:Hysteroscopy; D007834:Lasers; D007889:Leiomyoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014599:Uterus / Q000473:pathology
D007987:Gonadotropin-Releasing Hormone