title: Epidermal growth factor receptor mRNA in livers from newborn, adult and partially hepatectomized rats.
abstract: Epidermal growth factor (EGF) receptor mRNA expression in livers of newborn, adult control and partially hepatectomized rats 1 and 3 days post-operation was examined by Northern blot analysis. A human EGF receptor cDNA (P 64-1, Ullrich et al., 1984) was hybridized to RNA species of 10, 6 and 3 kb. These mRNAs were profoundly decreased in livers from newborn rats and relatively decreased in regenerating rat livers. beta-Actin mRNA in these tissues showed a tendency to increase over that of the adult controls.
authors: Division of Physiology, Tottori University School of Medicine, Yonago, Japan.
authors: Y
authors: Y
authors: Satoh
authors: Y
authors: Y
authors: Hoshikawa
authors: S
authors: S
authors: Ichii
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000378:metabolism*; D015152:Blotting, Northern; D066246:ErbB Receptors / Q000235:genetics*; D006498:Hepatectomy; D008099:Liver / Q000737:chemistry* / Q000254:growth & development / Q000502:physiology; D008297:Male; D012333:RNA, Messenger / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D012333:RNA, Messenger; D066246:ErbB Receptors