[Methotrexate induced pulmonary disease].
Methotrexate may cause pulmonary side effects. Two cases of methotrexate-induced fibrosing alveolitis are reported. One of the patients died from perforated gastric ulcer, the other was successfully treated with systemic steroids. The pulmonary side effects of methotrexate are reviewed. The most common clinical manifestation is fibrosing alveolitis. Pulmonary fibrosis and acute, non-cardiogenic pulmonary oedema are rare.
Sundset
A
A
Medisinsk avdeling, Aker sykehus, Oslo.
Ellingsen
I
I
Bergholtz
B
B
D000368:Aged; D005260:Female; D006801:Humans; D008168:Lung / Q000187:drug effects / Q000473:pathology; D008727:Methotrexate / Q000009:adverse effects*; D011658:Pulmonary Fibrosis / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography
D008727:Methotrexate
Metotrexatindusert lungesykdom.