The biology of myelopoiesis.
The myelopoietic system includes the hematopoietic cells derived from a common hematopoietic stem cell that includes erythroid, granulocytic, monocytic, and megakaryocytic lineages. The contributions of molecular genetic techniques to hematopoiesis in the past 5 years have led to quantum leaps in our understanding, but there is room for further research. Current concepts of stem cells and the hematopoietic microenvironment are discussed, as are committed progenitor cells and hematopoietic growth factors, particularly those concerning the neutrophilic, monocytic, and erythroid systems.
Nelson
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Department of Pathology, State University of New York Health Science Center, Syracuse.
D000818:Animals; D001853:Bone Marrow / Q000502:physiology; D001854:Bone Marrow Cells; D003115:Colony-Stimulating Factors / Q000502:physiology; D006410:Hematopoiesis; D006412:Hematopoietic Stem Cells / Q000166:cytology; D006801:Humans
D003115:Colony-Stimulating Factors