[Postradiation cancer of oral and maxillofacial regions].
Twenty-two patients with postradiation cancer of oral and maxillofacial regions treated in our hospital from 1969 to 1985 are reported. Of them, 3 patients had double postradiation cancers. The shortest interval between the two primary cancers was 3 years, the longest was 32 years with a median of 9 years. Of 15 patients treated with 60Co, 9 patients developed cancers and 6 sarcomas. In 4 patients treated with deep X-ray, cancers developed in 3 and sarcoma in one. Three patients were treated with 60Co, deep X-ray and radium implantation, all of them developed cancers. Radiation dose ranged from 3000 to 10,000 cGy but in most of the patients it was 7000-8000 cGy. In 19/22 patients the postradiation cancers were resected, giving 3 and 5 year survival rates of 50% and 23%. Only 1 patient survived for 14 years. Three patients treated by non-operative methods all died within 1-2 years. More aggressive treatments in patients with postradiation cancer are therefore indicated.
Lin
G C
GC
Ninth People's Hospital, Shanghai Second Medical College.
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000209:etiology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008441:Maxillary Neoplasms / Q000209:etiology / Q000601:surgery*; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000209:etiology / Q000601:surgery*; D009303:Nasopharyngeal Neoplasms / Q000532:radiotherapy*; D009381:Neoplasms, Radiation-Induced / Q000601:surgery*; D012509:Sarcoma / Q000209:etiology / Q000601:surgery*