Drugs and the bone marrow.
Some drugs have a predictable suppressive effect upon the bone marrow and are used in the treatment of malignant disease. Others are unpredictable and may cause unanticipated side effects to bone marrow during the treatment of non-malignant pathologies. In this article, bone marrow maturation is discussed and both the defined and potential effects of drugs upon the bone marrow are considered.
Treleaven
J
J
Royal Marsden Hospital, Sutton, Surrey, London.
Barrett
J
J
D000380:Agranulocytosis / Q000139:chemically induced / Q000628:therapy; D000741:Anemia, Aplastic / Q000139:chemically induced; D000744:Anemia, Hemolytic, Autoimmune / Q000139:chemically induced; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000494:pharmacology; D001853:Bone Marrow / Q000187:drug effects*; D004361:Drug Tolerance; D064420:Drug-Related Side Effects and Adverse Reactions; D006412:Hematopoietic Stem Cells / Q000187:drug effects*; D006801:Humans; D007938:Leukemia / Q000139:chemically induced
D000970:Antineoplastic Agents