[The isolation and characteristics of long-term continuous lymphoid cell lines (IK-10 and IK-12) from patients with mycosis fungoides].
Examinations of 26 cell cultures have detected in two cases continuous IK-10 and IK-12 cell lines from patients with mycosis fungoides. Studies of these cell ultrastructure, carried out by transmission electron microscopy, have shown organoids of all types, that are characteristic of both minor and medium lymphocytes and of lymphoblasts. Markers of T-, B-cells and mononuclears are also detectable in these cell lines. The cells express surface immunoglobulins and interleukin-2 receptors. Noteworthy that association of these cells in a population may be in vitro cultivated for more than 2 years.
Parfenova
T M
TM
Faradzhev
Z G
ZG
Kubanova
A A
AA
Shevliagin
V Ia
VIa
Chuvirov
G N
GN
Bykovskiĭ
A F
AF
D002460:Cell Line; D002469:Cell Separation; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000648:ultrastructure*; D010641:Phenotype; D012878:Skin Neoplasms / Q000648:ultrastructure*; D014407:Tumor Cells, Cultured / Q000648:ultrastructure
Poluchenie i kharakteristika dlitel'no perevivaemykh limfoidnykh kletochnykh liniĭ (IK-10 i IK-12) ot bol'nykh gribovidnym mikozom.