title: [Changes in cardiac hemodynamics, volume and pumping function of the heart ventricles in natural course of Fallot's tetrad].
abstract: The work analyses the results of repeated clinical and intracardiac examination of 13 patients with tetralogy of Fallot, conducted at the age of 23.1 +/- 9.9 and 42.3 +/- 13.1 months. The severity of the clinical condition grew markedly during natural course of tetralogy of Fallot (TF): the SaO2 value reduced from 71.8 +/- 7.2 to 65.0 +/- 8.0% and the blood hemoglobin level grew from 165 +/- 28 to 194 +/- 30 g/l. The data presented are evidence that in TF following a natural course a distinct tendency is displayed to growth of end diastolic volume of both ventricles in relation to the normal value and their dysfunction progresses in the form of reduction of the ejection fraction and increase of right-ventricular diastolic "rigidity". The results of the present work may be considered a substantiation of the tactics of early TF correction in infants and young children before the development of serious morphological changes and functional disorders.
authors: V N
authors: VN
authors: Il'in
authors: N A
authors: NA
authors: Chigogidze
mesh_terms: D002306:Cardiac Volume; D002675:Child, Preschool; D006321:Heart / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D007223:Infant; D008954:Models, Biological; D013318:Stroke Volume; D013771:Tetralogy of Fallot / Q000503:physiopathology* / Q000601:surgery
vernacular_title: Izmeneniia vnutriserdechnoĭ gemodinamiki, ob"ema i nasosnoĭ funktsii zheludochkov serdtsa pri estestvennom techenii tetrady Fallo.