[Diagnostic value of the lupus band test in patients treated by chronic hemodialysis].
The diagnosis of systemic lupus erythematosus in cases with advanced renal failure is a serious clinical problem. The purpose of the study was an analysis of the incidence of various non-renal criteria (according to ARA) for the diagnosis of SLE in patients with chronic renal failure of various aetiology and find out whether the lupus band test in these patients may serve as an additional criterion for the diagnosis of SLE. The studied group comprised 39 patients with chronic renal failure (28 men and 13 women) aged 17-58 years. In this group 29 cases were treated with dialyses and 10 conservatively. The most frequent clinical sign (apart from renal changes) accepted as diagnostic criteria for the SLE was polyserositis and leucopenia and thrombocytopenia. In no case antinuclear antibodies, antibodies against DNA and against soluble nuclear antigens were found. Positive LBT was obtained in 72.4% of cases with chronic renal failure, particularly frequently in the dialysed patients. A positive result of the LBT cannot be of decisive importance in the diagnosis of SLE but may suggest a need of more detailed investigations (determination of Ro antibodies) for confirmation of the diagnosis.
Billip-Tomecka
Z
Z
Kliniki Chorób Wewnetrznych AM w Warszawie.
Gellert
R
R
Błaszczyk
M
M
Jarzabek-Chorzelska
M
M
Switalski
M
M
Chorzelski
T
T
D000293:Adolescent; D000328:Adult; D003181:Complement C4 / Q000032:analysis*; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000276:immunology / Q000628:therapy*; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D012867:Skin / Q000276:immunology*
D003181:Complement C4; D007136:Immunoglobulins
Wartość diagnostyczna lupus band test u chorych przewlekle dializowanych.