title: The growth of circumferential scars of the major airways from infancy to adulthood.
abstract: The factors affecting the development and prognosis of scarred airways in children are presented from a long-term follow-up study of 14 cases of tracheobronchial lesions following either injury or operation. Four children managed by endoluminal treatment developed severe stenosis and required treatment, later as adults, by laser resection in 2 cases and by laryngotracheal plastic enlargement and resection with anastomosis in 1 case each. The follow-up of 7 children managed by plastic procedures showed inconsistent results: they were good or excellent in 3 cases but with a decrease in the laryngotracheal diameter of 36%, 28% and 7% respectively. The laryngotracheal calibre decreased in 2 patients to 45% due to partial fibrous stenosis. Resection and anastomosis was required in the remaining 2 patients after 11 and 12 years for severe re-stenosis. The 3 patients who underwent immediate surgical resection all had an excellent clinical and morphological result, with a decrease in the laryngotracheal diameter of only 7%, 13% and 19% after a follow-up of 18, 20 and 15 years, respectively. These results show that the growth capacity of scars in children's airways is closely related to residual sclerosis following the initial treatment. It is thus suggested that primary resection and anastomosis should be performed in as many cases as possible. In the performance of plastic procedures, special attention should be paid to complete resection of the fibrotic tissues. Finally, a very long postoperative follow-up is always required in children in order to assess the development of the airway.
authors: Thoracic Surgery Unit, Bordeaux II University, Xavier Arnozan Hospital, Pessac, France.
authors: L
authors: L
authors: Couraud
authors: J M
authors: JM
authors: Moreau
authors: J F
authors: JF
authors: Velly
mesh_terms: D000293:Adolescent; D002648:Child; D002921:Cicatrix / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007829:Laryngostenosis / Q000209:etiology / Q000473:pathology* / Q000601:surgery / Q000628:therapy; D007830:Larynx / Q000293:injuries / Q000473:pathology / Q000601:surgery; D008297:Male; D014132:Trachea / Q000293:injuries / Q000473:pathology / Q000601:surgery; D014135:Tracheal Stenosis / Q000209:etiology / Q000473:pathology* / Q000601:surgery / Q000628:therapy