[Functional activity of segmentonuclear neutrophils and monocytes in children with different cytologic variants of acute myeloid leukemia].
Bone marrow and blood neutrophils and monocytes were examined over time in 31 patients with different versions of acute myeloid leukemia according to the phagocytosis and NBT tests. As compared to the phagocytic indicators in healthy children, the absorptive activity in the acute disease period was increased and the digestive activity was lowered. Approximation of the digestive activity of blood neutrophils to the control data was only noted in long remissions (over 1 year). Function of mature cells together with other markers can be used as an initial sign of a favourable prognosis of the underlying disease.
Borodina
T M
TM
D002648:Child; D006801:Humans; D007948:Leukemia, Monocytic, Acute / Q000276:immunology*; D015470:Leukemia, Myeloid, Acute / Q000276:immunology*; D015479:Leukemia, Myelomonocytic, Acute / Q000276:immunology*; D009000:Monocytes / Q000276:immunology*; D009504:Neutrophils / Q000276:immunology*; D010587:Phagocytosis / Q000276:immunology*; D011379:Prognosis
Funktsional'naia aktivnost' segmentoiadernykh neĭtrofilov i monotsitov u deteĭ z razlichnymi tsitologicheskimi variantami ostrogo mieloleĭkoza.