Ethnopharmacology of rhinoceros horn. I: Antipyretic effects of rhinoceros horn and other animal horns.
Intraperitoneal administration of an aqueous extract of rhinoceros horn at 5, 2.5 and 1 g/ml, showed a significant antipyretic effect in rats with hyperthermia induced by subcutaneous injection of terpentine oil. Similar assays with extracts of the horns of saiga antelope, water buffalo and cattle at 5 g/ml also caused a significant drop in fever; however, at 1 g/ml, only saiga antelope horn produced an antipyretic action.
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Department of Biology, Chinese University of Hong Kong, Shatin, N.T.
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D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D001831:Body Temperature / Q000187:drug effects; D002020:Buffaloes; D002417:Cattle; D006733:Horns; D008297:Male; D008516:Medicine, Chinese Traditional; D010527:Perissodactyla / Q000033:anatomy & histology*; D051381:Rats; D011919:Rats, Inbred Strains; D014020:Tissue Extracts / Q000494:pharmacology*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D014020:Tissue Extracts