Neutrophilic eccrine hidradenitis in two neutropenic patients.
Neutrophilic eccrine hidradenitis is an uncommon, self-limited dermatosis with a variable clinical presentation. It seems to be due to chemotherapeutic drugs in most cases. Necrosis of the eccrine gland associated with a neutrophilic infiltrate is the histologic hallmark of this disease. We report two additional cases in neutropenic patients with acute myelogenous leukemia in which there was a striking lack of neutrophil infiltration. A new term, drug-associated eccrine hidradenitis, is suggested.
Allegue
F
F
Department of Dermatology, Hospital Ramón y Cajal, Madrid, Spain.
Soria
C
C
Rocamora
A
A
Muñoz
E
E
Freire-Murgueytio
P
P
Arrazola
J M
JM
Ledo
A
A
D000293:Adolescent; D000970:Antineoplastic Agents / Q000009:adverse effects; D004439:Eccrine Glands / Q000473:pathology; D006801:Humans; D007249:Inflammation / Q000139:chemically induced / Q000473:pathology; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000473:pathology*; D012867:Skin / Q000473:pathology; D013543:Sweat Gland Diseases / Q000139:chemically induced / Q000473:pathology*
D000970:Antineoplastic Agents