[Cardiologic side effects of therapeutic irradiation of breast cancer--early results].
Authors prospectively examined 54 breast-cancer patients treated by postoperative telecobalt (28), or electron therapy (26). They studied the cardiological side-effects caused by ionizing radiation. ECG, echocardiography and measurement of the systolic time intervals were performed before, immediately, 6 weeks, 6 months, one and 1.5-2 yrs after the completion of radiotherapy. Twenty-three symptom-free patients were found to have signs of transitorial pericardial irritation, more after telecobalt, than electron therapy (17/6). T-wave inversions were seen on the ECG of twenty patients. In 5 and 3 patients small amounts of pericardial effusion could be detected by echocardiography with, or without ECG alterations, respectively. Other side-effects mentioned by the literature could not be found yet, further follow-up is recommended, however. In the authors' opinion the effect of ionizing radiation, mainly of telecobalt therapy is possibly a risk factor for cardiovascular diseases, it is suggested to be considered at the planning of radiation therapy accordingly.
Gyenes
G
G
Semmelweis Orvostudományi Egyetem, Budapest.
Faragó
K
K
D000328:Adult; D001943:Breast Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D003037:Cobalt Radioisotopes / Q000009:adverse effects*; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000528:radiation effects; D006331:Heart Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D008297:Male; D008408:Mastectomy; D008875:Middle Aged; D011182:Postoperative Care; D011867:Radioisotope Teletherapy / Q000009:adverse effects*; D014463:Ultrasonography
D003037:Cobalt Radioisotopes
Emlörákos betegek kuratív besugárzásának kardiológiai mellékhatásai--korai eredmények.