[Current overview of diagnostic possibilities of complement analysis].
The complement system is composed of at least 21 serum proteins and 8 cell surface receptors sensitive to complement components or their fragments. Qualitative and quantitative analysis of complement components in clinical samples has become standard procedure in many laboratories thanks to the availability of easy-to-perform test kits. However, interpretation of results is still a task that requires great skill and the situation are rare, in which analysis of the complement system goes beyond diagnosis into therapeutic consequences. The present paper is an update of previous similar reviews now available in the international literature; in addition, the author attempts at bringing the often complicated world of complement and clinical practice together and thus contributes to answering the question: what should the clinician know about complement?
Nydegger
U
U
Hämatologischen Zentrallabor Inselspitals, Bern, Schweiz.
D000936:Antigen-Antibody Complex / Q000276:immunology; D001327:Autoimmune Diseases / Q000276:immunology*; D003167:Complement Activation / Q000276:immunology; D003170:Complement Pathway, Alternative / Q000276:immunology; D003171:Complement Pathway, Classical / Q000276:immunology; D003165:Complement System Proteins / Q000032:analysis*; D006801:Humans; D007239:Infections / Q000276:immunology*; D007249:Inflammation / Q000276:immunology*; D011951:Receptors, Complement / Q000502:physiology
D000936:Antigen-Antibody Complex; D011951:Receptors, Complement; D003165:Complement System Proteins
Aktuelle Zusammenstellung diagnostischer Möglichkeiten der Komplementanalytik.