Characterization of premotor interneurones by their input patterns--application of principal component analysis to cat cervical interneurones.
Principal component analysis of input patterns of cat C6-C8 interneurones (300 cells) revealed that identified premotor interneurones (11 cells) activated from skin afferents and projecting to T1 motoneurones possessed a special input pattern, characterized by restricted distribution on the plane of the first (Prin 1) versus second (Prin 2) principal component (high positive values of both components). These premotor neurones were located mostly in laminae V-VI. Among other laminae V-VI cells descending in the lateral funiculus to T1 similar to such premotor neurones, there were cells distributed similarly on the Prin 1-2 plane. Further, a majority of interneurones antidromically activated from the T1 motor nucleus at low thresholds also showed a distribution on the plane similar to the premotor neurones. We suggest that premotor neurones of this input pattern constitute a major group among laminae V-VI premotor neurones projecting to T1.
Kitazawa
S
S
Department of Neurophysiology, Faculty of Medicine, University of Tokyo, Japan.
Ohki
Y
Y
Xi
M C
MC
D000818:Animals; D002415:Cats; D005528:Foot / Q000294:innervation; D007395:Interneurons / Q000502:physiology*; D009046:Motor Neurons / Q000502:physiology; D009475:Neurons, Afferent / Q000502:physiology; D012867:Skin / Q000294:innervation; D013116:Spinal Cord / Q000166:cytology* / Q000502:physiology