Massive histamine release in a patient with systemic mastocytosis.
We have measured plasma histamine concentrations, systemic vascular resistance, cardiac output and arterial pressure during laparotomy in a patient with systemic mastocytosis. The patient developed vasodilation and hypotension during surgery, associated with a massive increase in plasma histamine concentration.
Desborough
J P
JP
Department of Anesthestic, Royal Postgraduate Medical School, Hammersmith Hospital, London.
Taylor
I
I
Hattersley
A
A
Garden
A
A
Wolff
A
A
Bloom
S R
SR
Morgan
M
M
D000768:Anesthesia, General; D001794:Blood Pressure; D002302:Cardiac Output; D006632:Histamine / Q000097:blood*; D006801:Humans; D007022:Hypotension / Q000209:etiology*; D007431:Intraoperative Complications / Q000209:etiology; D007813:Laparotomy; D008297:Male; D008415:Mastocytosis / Q000097:blood* / Q000503:physiopathology; D008875:Middle Aged; D012769:Shock / Q000209:etiology*; D014655:Vascular Resistance
D006632:Histamine