Blink reflex recovery after electrical stimulation of the reinnervated orbicularis oculi muscle in dogs.
The paralytic lagophthalmos following palpebral nerve neurotmesis and consequent peripheral denervation of the orbicularis oculi muscle is often associated with harmful effects on the exposed cornea. This study investigated how daily electrical stimulation affects the blink reflex recovery of this muscle after its reinnervation. Six dogs underwent unilateral facial nerve neurotmesis with immediate epineurial repair of the palpebral nerve. Three dogs were randomly chosen to receive electrical stimulation of the reinnervated orbicularis oculi muscles for 75 days. The remaining 3 dogs were controls (nonstimulated muscles). During the study, the reinnervated orbicularis oculi muscle electrophysiology and blink reflex recovery were investigated. The Student's t test was used for statistical analysis. The results can be summarized as follows: (1) between 30 and 50 days, the minimum mean stimulus intensities evoking complete up-per palpebral closure of the stimulated muscles were significantly lower than those of the nonstimulated muscles (p less than 0.01) and (2) the stimulated muscles recovered complete closure of the interpalpebral fissure (blink reflex) at 49.6 days, significantly earlier (p less than 0.01) than the nonstimulated muscles (72.6 days). It is concluded that daily electrical stimulation of the orbicularis oculi muscles, if started immediately after epineurial repair of the palpebral nerve neurotmesis, promotes a faster blink reflex recovery in the dog model.
Salerno
G M
GM
Division of Plastic and Reconstructive Surgery, Creighton University School of Medicine, Omaha, NE 68131.
Bleicher
J N
JN
Stromberg
B V
BV
D000818:Animals; D001767:Blinking / Q000502:physiology*; D004285:Dogs; D004558:Electric Stimulation; D004599:Electric Stimulation Therapy; D005141:Eyelid Diseases / Q000628:therapy; D005143:Eyelids / Q000294:innervation* / Q000502:physiology; D009119:Muscle Contraction; D009121:Muscle Denervation