Interaction of dietary protein content and exogenous porcine growth hormone administration on protein and lipid accretion rates in growing pigs.
Sixty-six intact male pigs were used to investigate the relationships between exogenous porcine growth (pGH) administration (0, excipient-treated, and .09 mg recombinant pGH.kg-1.d-1) and dietary protein content (8.3, 11.4, 14.5, 17.6, 20.7 and 23.8%) on protein and lipid accretion rates over the live weight range of 30 to 60 kg. Feed intakes were restricted (1.84 kg.pig-1.d-1) and pGH was administered daily by i.m. injection. Rate of protein deposition increased with increasing dietary protein up to 17.6 and 20.7%, respectively, for control and pGH-treated pigs; both growth and protein deposition were enhanced by pGH on the four higher protein diets but remained unaffected by pGH administration to pigs given the two lowest protein diets. Plasma IGF-I concentration was elevated by pGH administration in pigs given the four higher protein diets but unaffected by pGH with the two lowest protein diets. Rate of fat deposition was depressed on all dietary protein treatments by pGH administration; carcass fat content of control and pGH-treated pigs declined with each increase in dietary protein up to 17.6 and 23.8%, respectively. The results demonstrate that pGH acts independently on protein and lipid metabolism.
Campbell
R G
RG
Animal Research Institute, Werribee, Victoria, Australia.
Johnson
R J
RJ
King
R H
RH
Taverner
M R
MR
Meisinger
D J
DJ
D000273:Adipose Tissue / Q000254:growth & development; D000818:Animals; D004044:Dietary Proteins / Q000494:pharmacology*; D013006:Growth Hormone / Q000494:pharmacology*; D050356:Lipid Metabolism; D008297:Male; D024510:Muscle Development; D011506:Proteins / Q000378:metabolism*; D012044:Regression Analysis; D013552:Swine / Q000254:growth & development / Q000378:metabolism*
D004044:Dietary Proteins; D011506:Proteins; D013006:Growth Hormone