[A child with neonatal allo-immune neutropenia].
A newborn child with neonatal neutropenia as a result of the presence of maternal IgG isoantibodies against neutrophil granulocyte blood group antigens is reported. Mechanism, diagnostics and therapy of the disease are discussed. The diagnosis not only has consequences for the child, but also for the mother and following pregnancies. A review of the most important causes of neonatal neutropenia is given.
Markhorst
D G
DG
Afd. Kindergeneeskunde, Academisch Ziekenhuis der Vrije Universiteit, Amsterdam.
Hack
W W
WW
de Waal
F C
FC
Kuypers
R
R
D001789:Blood Group Antigens / Q000276:immunology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000276:immunology; D007518:Isoantibodies / Q000276:immunology*; D008297:Male; D008431:Maternal-Fetal Exchange; D009503:Neutropenia / Q000151:congenital / Q000276:immunology*; D011247:Pregnancy
D001789:Blood Group Antigens; D007518:Isoantibodies
Een kind met neonatale allo-immuun neutropenie.