[The effect of the delta-sleep peptide on the adrenaline level in rat tissues under normal conditions and during cold stress].
Adrenalin content in the brain, liver and adrenal glands under the effect of cold stress grows by 314, 500 and 56% as compared to the control. A single administration of the delta-sleep inducing peptide (DSIP) in a dose of 12 microgram/100 g to intact animals makes the adrenalin content in the brain higher 1, 3, 6 and 24h after administration; two and three days later the adrenalin content in the brain does not change. The amount of adrenalin in the liver of the same animals increases 1, 3, 6 h and 1, 2, 3 days after DSIP administration. Intraperitoneal administration of DSIP induces an increase of the adrenalin level in the adrenal glands of rats an hour and a day after administration. Two days later the level of adrenaline decreases by 41%; 3, 6 h and 3 days after DSIP administration the content of adrenaline remains unchanged. As a result of the DSIP administration in a dose of 12 micrograms/100 g to the animals in the state of cold stress, the content of adrenalin increases in the rat brain by 129, in the liver--by 300, adrenal glands--by 44% as compared with the control.
Bondarenko
T I
TI
Krichevskaia
A A
AA
Sheĭkina
I V
IV
Kiriukhina
E V
EV
D000311:Adrenal Glands / Q000737:chemistry / Q000187:drug effects; D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects; D003080:Cold Temperature; D003701:Delta Sleep-Inducing Peptide / Q000494:pharmacology*; D004837:Epinephrine / Q000032:analysis*; D008099:Liver / Q000737:chemistry / Q000187:drug effects; D008297:Male; D051381:Rats; D013312:Stress, Physiological / Q000378:metabolism*
D003701:Delta Sleep-Inducing Peptide; D004837:Epinephrine
Vliianie peptida del'ta-sna na soderzhanie adrenalina v tkaniakh krys v norme i pri deĭstvii kholodnovogo stressa.