title: Possible methodologies for the detection and study of DNA sequence changes following mutagen exposure: magnetic enrichment in mutant DNA.
abstract: The restriction site mutation method described by Parry et al. (1990) for isolating mutant sequences directly from DNA is discussed and an additional enrichment step proposed using magnetic beads.
authors: MRC Cell Mutation Unit, University of Sussex, Falmer, Brighton, UK.
authors: B A
authors: BA
authors: Bridges
authors: A M
authors: AM
authors: Carr
authors: A R
authors: AR
authors: Lehmann
mesh_terms: D000818:Animals; D001483:Base Sequence; D004247:DNA / Q000187:drug effects / Q000235:genetics*; D005821:Genetic Techniques; D008280:Magnetics; D016296:Mutagenesis; D009153:Mutagens / Q000494:pharmacology*; D016133:Polymerase Chain Reaction / Q000379:methods; D015183:Restriction Mapping
chemical_list: D009153:Mutagens; D004247:DNA