Determination of salicilic acid in saliva by high-performance liquid chromatography.
A sensitive reversed-phase HPLC method with fluorimetric detection was developed for the determination of salicilic acid in saliva samples. The method, involving a preliminary solid-phase extraction procedure, was found to be suitable for the determination of salivary salicilic acid concentrations following the administration of a single oral dose of some commercial acetylsalicilic acid formulations.
Cavrini
V
V
Dipartimento di Scienze Farmaceutiche, Università, Bologna, Italy.
Gatti
R
R
Di Pietra
A M
AM
D001241:Aspirin / Q000032:analysis; D001682:Biological Availability; D002851:Chromatography, High Pressure Liquid; D006801:Humans; D012459:Salicylates / Q000032:analysis*; D020156:Salicylic Acid; D012463:Saliva / Q000737:chemistry*
D012459:Salicylates; D020156:Salicylic Acid; D001241:Aspirin