title: Growth control in mammalian cells by cell-cell contacts.
abstract: Growth of normal diploid mammalian cells in vitro is strongly regulated by the actual cell density. Cell-cell contacts via specific plasma membrane glycoproteins whose glycan moieties interact with specific receptors has been found to be a main growth regulatory principle. Malignant growth is suggested to result from impaired function of these receptors.
authors: Institute of Toxicology, Johannes Gutenberg University, Mainz, Federal Republic of Germany.
authors: R J
authors: RJ
authors: Wieser
authors: D
authors: D
authors: Renauer
authors: A
authors: A
authors: Schäfer
authors: R
authors: R
authors: Heck
authors: R
authors: R
authors: Engel
authors: S
authors: S
authors: Schütz
authors: F
authors: F
authors: Oesch
mesh_terms: D002448:Cell Adhesion / Q000502:physiology; D002449:Cell Aggregation / Q000502:physiology; D002450:Cell Communication / Q000502:physiology*; D002455:Cell Division / Q000502:physiology*; D003260:Contact Inhibition / Q000502:physiology; D006801:Humans; D010980:Platelet Membrane Glycoproteins / Q000737:chemistry / Q000502:physiology*
chemical_list: D010980:Platelet Membrane Glycoproteins