Additional salutary hemodynamic effects of the combined use of the paraaortic counterpulsation device and intraaortic balloon pump versus a paraaortic counterpulsation device alone.
The hemodynamic effects of the combined use of the paraaortic counterpulsation device (PACD) (stroke volume 65 ml) implanted on the ascending aorta, and a 20 ml intraaortic balloon pump (IABP) placed in the descending aorta, were compared with the PACD working alone in 12 dogs after the induction of heart failure. Heart failure was characterized by left ventricular end-diastolic pressure (LVEDP) greater than 18 mmHg and systolic aortic pressure (SAP) in stage A: 116 mmHg greater than or equal to SAP greater than 70 mmHg; in stage B: 70 mmHg greater than or equal to SAP greater than 30 mmHg; and in stage C: SAP less than or equal to 30 mmHg. Both modalities of mechanical assistance produced significant salutary hemodynamic effects in stages A and B. No difference was observed in stage C. In conclusion, the combined use of PACD and IABP is more effective than the use of either of these devices alone. This modality of mechanical assistance may easily be applied in patients that cannot be weaned from extracorporeal circulation, and in whom IABP was unsuccessfully applied.
Nanas
J N
JN
Department of Clinical Therapeutics, University of Athens, Greece.
Poyiadjis
A
A
Charitos
C
C
Nanas
S N
SN
Kontoyiannis
D
D
Anastasiou-Nana
M
M
Alevizakos
N
N
Voudris
V
V
Moulopoulos
S D
SD
D000818:Animals; D002302:Cardiac Output / Q000502:physiology; D003131:Combined Modality Therapy; D015908:Counterpulsation / Q000295:instrumentation*; D004285:Dogs; D006333:Heart Failure / Q000503:physiopathology; D006439:Hemodynamics / Q000502:physiology*; D007423:Intra-Aortic Balloon Pumping / Q000295:instrumentation*; D008955:Models, Cardiovascular; D016277:Ventricular Function, Left / Q000502:physiology