Fulminant myasthenia gravis soon after initiation of acebutolol therapy.
We report the case of myasthenia gravis in a 74-year-old woman, 2 weeks after acebutolol had been introduced as the sole treatment for systemic hypertension. The disease developed at a fulminant and fatal course despite drug withdrawal. The possibilities of coincidental association between the two events, triggering of a preexisting latent myasthenia gravis or full induction of the disease by acebutolol, are discussed.
Confavreux
C
C
Hôpital Neurologique, Lyon, France.
Charles
N
N
Aimard
G
G
D000070:Acebutolol / Q000008:administration & dosage / Q000009:adverse effects*; D000368:Aged; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004576:Electromyography / Q000187:drug effects; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D009157:Myasthenia Gravis / Q000139:chemically induced*; D009460:Neurologic Examination
D000070:Acebutolol