Fine-needle cytology of solid tumors: method, diagnostic accuracy, and role in management.
Fine-needle cytology was obtained from 14 solid tumors in 12 children. Both aspiration and nonaspiration techniques were used and several staining methods were applied. May Grünwald Giemsa and Papanicolaou stains were preferred. The nonaspiration method yielded a superior quality cytology smear with less blood contamination. There were no complications recorded. Confirmation of the diagnosis with cytology allowed for planned management with preoperative cytotoxic chemotherapy and/or radiotherapy in 10 children, immediate surgery in one, and radiotherapy to a vertebral recurrence in one. Fine-needle cytology is considered a useful technique in the management of a selected group of children with solid tumors.
Millar
A J
AJ
Department of Paediatric Surgery, Red Cross War Memorial Children's Hospital, Cape Town, Africa.
Sinclair-Smith
C
C
Rode
H
H
Hartley
P
P
Karabus
C
C
Cywes
S
S
D001707:Biopsy, Needle / Q000379:methods* / Q000592:standards; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D009369:Neoplasms / Q000175:diagnosis / Q000473:pathology*