[Structure and properties of collagen in leukemia].
Collagen I was isolated from human bone tissue and from mice bone tissue of the AKR-50 strain at the pronounced stage of leukosis. Dissimilarity of native and leukemic collagens was exhibited after evaluation of their amino acid composition, electrophoretic mobility in polyacrylamide gel containing SDS, content of the carbohydrate moiety as well as of isopoints, elution profiles in reverse-phase chromatography and gel filtration and electron microscopy of SLS-crystallites. Impairments of collagen processing in leukemia appear to be responsible for its alterations in structure and properties.
Volodina
T T
TT
Drozdova
V D
VD
Pechenova
T N
TN
Shimanovskaia
A K
AK
Nartikov
A V
AV
Nosal'
N A
NA
Boĭko
V B
VB
Bebeshko
V G
VG
Gulyĭ
M F
MF
D000293:Adolescent; D000596:Amino Acids / Q000737:chemistry; D000818:Animals; D002648:Child; D002675:Child, Preschool; D002851:Chromatography, High Pressure Liquid; D003094:Collagen / Q000737:chemistry* / Q000648:ultrastructure; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007223:Infant; D007525:Isoelectric Focusing; D051379:Mice; D008806:Mice, Inbred AKR; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000378:metabolism* / Q000473:pathology
D000596:Amino Acids; D003094:Collagen
Osobennosti struktury i svoĭstv kollagena pri leĭkoze.