[Pharmacokinetic modeling in clinical practice: pefloxacin].
Pharmacokinetic modelling allows to set up a therapeutic plan for administering a drug. The advances of this procedure are particularly remarkable in drugs discharged by the liver. The principles of this approach are presented and illustrated on the treatment with pefloxacin. The potential causes of the adverse effect of the drug observed in one patient of the series studied could thus be suggested.
Dzúriková
V
V
Výskumného ústavu lekárskej bioniky v Bratislave.
Krechnáková
A
A
Svĕtlovská
E
E
Spustová
V
V
Gajdos
M
M
Krivosíková
Z
Z
Dzúrik
R
R
D003198:Computer Simulation; D006801:Humans; D007262:Infusions, Intravenous; D007676:Kidney Failure, Chronic / Q000378:metabolism; D015366:Pefloxacin / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000627:therapeutic use
D015366:Pefloxacin
Farmakokinetické modelovanie v klinickej praxi: pefloxacín.