Distribution of GABA-like immunoreactivity in guinea pig vestibular cristae ampullaris.
Post-embedding immunocytochemical techniques were used to assess distribution of gamma-aminobutyric acid (GABA) in the guinea pig cristae ampullaris. GABA-like immunoreactivity (GABA-LIR) was found in the cytoplasm of both type I (HCI) and type II hair cells (HCII), in the afferent calyx (AC) contacting HCI and some myelinated fibers in the subjacent stroma. HCI and its calyceal contacts showed variation in GABA-LIR, suggesting different populations in HCI and AC. These results support a putative afferent neurotransmitter role of GABA in HC and a possible degradation site of GABA in AC.
López
I
I
Departamento de Neurociencias, Instituto de Fisiología Celular, UNAM, México D.F. México.
Juiz
J M
JM
Altschuler
R A
RA
Meza
G
G
D000818:Animals; D005260:Female; D006168:Guinea Pigs; D007124:Immunoenzyme Techniques; D008297:Male; D014722:Vestibule, Labyrinth / Q000737:chemistry* / Q000648:ultrastructure; D005680:gamma-Aminobutyric Acid / Q000032:analysis*
D005680:gamma-Aminobutyric Acid