[Interrelation between static parameters of trabecular bones in acromegaly, the STH levels and the duration of the condition. Histomorphometric study].
To evaluate trabecular bone formations of active acromegalic patients the authors used the method of histomorphometry and correlated the calculated variables of the trabecular volume (V), osteoid volume (Vos), osteoid surface (Sf) and width of the osseous trabeculum (MTT) with STH levels, the patients' age and the period of the acromegalic process. No correlations were found between Vos, Sf, MTT and STH levels, age and the length of the case-history. There were negative correlations (p less than 0.05) between the trabecular volume (V) and the period of the case-history and trabecular volume (V) and the patients' age. From the results it may be concluded that STH does not influence the balance between resorption and formation of the acromegalic spongiosa in favour of formation.
Zák
J
J
III. interní katedra 1. lékarské fakulty Univerzity Karlovy, Praha.
Povýsil
C
C
Pacovský
V
V
Marek
J
J
D000172:Acromegaly / Q000097:blood / Q000473:pathology*; D000328:Adult; D001842:Bone and Bones / Q000473:pathology*; D013006:Growth Hormone / Q000097:blood*; D006801:Humans; D008875:Middle Aged; D013997:Time Factors
D013006:Growth Hormone
Souvislost statických parametrů akromegalické trabekulární kosti s hladinami STH a délkou anamnézy. Histomorfometrickástudie.