Studies of the mode of action of anthelmintic drugs: tools to investigate the biochemical peculiarities of helminths.
An overview is given of the results from mode of action studies which improved our knowledge of some biochemical and/or electrophysiological aspects of parasitic helminths. Studies of the molecular mechanism of action of for example, antimonials, piperazine, levamisole, ivermectin, salicylanilides, praziquantel, benzimidazole carbamates, oxamniquine and hycanthone offered tools to learn more of the parasites and their hosts.
Vanden Bossche
H
H
Department of Comparative Biochemistry, Janssen Research Foundation, Beerse, Belgium.
D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology*; D050260:Carbohydrate Metabolism; D006376:Helminths / Q000187:drug effects* / Q000502:physiology; D008563:Membrane Lipids / Q000502:physiology; D009132:Muscles / Q000187:drug effects; D009420:Nervous System / Q000187:drug effects
D000871:Anthelmintics; D008563:Membrane Lipids