title: Electron microscopy study of human myeloma immunoglobulin G1.
abstract: Human immunoglobulin G1 Van was studied by negative staining, freeze drying and high resolution shadow casting. The Fab and Fc subunits of an intact IgG1 molecule were shown to possess limited mobility. It was found that about 70% of molecules in the IgG1 Van specimen are not flat but have a tripod-like shape.
authors: Institute of Immunology, Moscow Region, Chekhov District, USSR.
authors: S N
authors: SN
authors: Ryazantsev
authors: V M
authors: VM
authors: Abramov
authors: V P
authors: VP
authors: Zav'yalov
authors: V D
authors: VD
authors: Vasiliev
mesh_terms: D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000648:ultrastructure; D007074:Immunoglobulin G / Q000648:ultrastructure*; D008854:Microscopy, Electron; D009194:Myeloma Proteins; D011487:Protein Conformation
chemical_list: D007140:Immunoglobulin Fab Fragments; D007074:Immunoglobulin G; D009194:Myeloma Proteins