Determination of lysergic acid diethylamide (LSD) in urine by instrumental high-performance thin-layer chromatography.
An instrumental high-performance thin-layer chromatographic (HPTLC) technique for the determination of lysergic acid diethylamide (LSD) in urine was developed. Before chromatographic separation, a single-step extraction with alkaline wash is performed. The procedure can detect less than 1 microgram LSD/L urine. Results of HPTLC determination are compared with those from a radioimmunoassay (RIA) procedure.
Blum
L M
LM
National Medical Services, Inc., Willow Grove, Pennsylvania 19090.
Carenzo
E F
EF
Rieders
F
F
D002855:Chromatography, Thin Layer; D006801:Humans; D007202:Indicators and Reagents; D008238:Lysergic Acid Diethylamide / Q000652:urine*; D011863:Radioimmunoassay; D013050:Spectrometry, Fluorescence
D007202:Indicators and Reagents; D008238:Lysergic Acid Diethylamide