Association of microscopic gonadoblastoma and contralateral ovarian fibroadenoma in patients with gonadal dysgenesis and Turner phenotype.
A rare case of microscopic gonadoblastoma associated with gonadal fibroadenoma in a patient with gonadal dysgenesis and Turner phenotype is reported. The higher incidence of tumor pathologies in patients with gonadal dysgenesis presenting a Y chromosome in their karyotype is discussed, and the need for judicious microscopic analysis of the gonadal streaks of these patients for the detection of possible incipient tumors is emphasized.
de Sá
M F
MF
Department of Gynecology and Obstetrics, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Brazil.
de Moura
M D
MD
Ferriani
R A
RA
Velludo
M A
MA
Soares
L R
LR
Cavalcanti
D P
DP
D000232:Adenofibroma / Q000473:pathology*; D000293:Adolescent; D004407:Dysgerminoma / Q000473:pathology*; D005260:Female; D006066:Gonads / Q000473:pathology; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010641:Phenotype; D014424:Turner Syndrome / Q000150:complications / Q000235:genetics / Q000473:pathology*