title: Indices of intact serum parathyroid hormone and renal excretion of calcium, phosphate, and magnesium.
abstract: Up to date reference ranges were established for fasting renal excretion of calcium, phosphorus, and magnesium on 101 healthy children aged 2-15 years. A normal range for intact parathyroid hormone was also measured. The indices of calcium and magnesium excretion showed no correlation with age or sex so that a common range for all children could be established. The 97th centile values for urinary calcium:creatinine and magnesium:creatinine ratios were 0.69 mmol:mmol and 1.05 mmol:mmol respectively. The calculated tubular maximum for phosphate/litre of glomerular filtrate (TmPO4/GFR) showed no correlation with age with a geometric mean value of 1.67 mmol/l. The normal range for intact serum parathyroid hormone for the age group was 11-35 ng/l, which is lower than the adult normal range using the same assay. There was an inverse correlation between TmPO4/GFR and intact parathyroid hormone in this group of normal children.
authors: Department of Paediatrics and Child Health, St James's University Hospital, Leeds.
authors: N J
authors: NJ
authors: Shaw
authors: J
authors: J
authors: Wheeldon
authors: J T
authors: JT
authors: Brocklebank
mesh_terms: D000293:Adolescent; D002118:Calcium / Q000652:urine*; D002648:Child; D002675:Child, Preschool; D003404:Creatinine / Q000652:urine; D005215:Fasting / Q000378:metabolism; D005260:Female; D005919:Glomerular Filtration Rate / Q000502:physiology; D006801:Humans; D007668:Kidney / Q000378:metabolism*; D008274:Magnesium / Q000652:urine*; D008297:Male; D010281:Parathyroid Hormone / Q000097:blood*; D010756:Phosphoric Acids / Q000652:urine*; D012016:Reference Values
chemical_list: D010281:Parathyroid Hormone; D010756:Phosphoric Acids; D003404:Creatinine; C030242:phosphoric acid; D008274:Magnesium; D002118:Calcium