title: [Inhibition of caries by Na-saccharin].
abstract: The inhibition of dental caries by Na-saccharin was studied in an optimized and standardized experiment with cara rats. The animals were given a cariogenic diet ad libitum as well as under controlled frequency feeding conditions. The addition of 0.5% Na-saccharin to the cariogenic diet produced no cariostatic effects. Ancilliary microbiological in vitro and in vivo experiments showed no appreciable bacteriostatic effects on the cariogenic bacteria flora.
authors: Universität Wurzburg.
authors: E J
authors: EJ
authors: Karle
authors: F
authors: F
authors: Gehring
mesh_terms: D000818:Animals; D003731:Dental Caries / Q000517:prevention & control*; D003773:Dental Plaque / Q000382:microbiology*; D004037:Diet, Cariogenic; D051381:Rats; D012439:Saccharin / Q000378:metabolism*
chemical_list: D012439:Saccharin
vernacular_title: Zur kariostatischen Wirkung von Na-Saccharin.