title: [The extracellular epidermal compartment of mammals].
abstract: The structure and function of the intercorneocyte cement of the corneal layer of epidermis in mammals has been reviewed on the basis of the author's and published data. Two functions of the layer have been considered: a water-tight barrier and a desquamation. Chemical structure of the barrier has been characterized. Comparison of the barrier in water and terrestrial mammals suggest that the peculiarities of the barrier correlate with different pathways of keratinization. Factors that determine the adhesion have been described. The authors show the possibility to use natural models for studying the processes of keratinization and, in particular, functioning the intercellular compartment of the corneal layer.
authors: V E
authors: VE
authors: Sokolov
authors: L V
authors: LV
authors: Stepanova
mesh_terms: D000663:Amphibians; D000818:Animals; D002448:Cell Adhesion / Q000502:physiology; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D000078404:Epidermal Cells; D004817:Epidermis / Q000502:physiology; D005110:Extracellular Space / Q000502:physiology*; D015603:Keratinocytes / Q000166:cytology / Q000502:physiology; D008322:Mammals / Q000033:anatomy & histology*; D008563:Membrane Lipids / Q000502:physiology; D008954:Models, Biological; D013499:Surface Properties
chemical_list: D008563:Membrane Lipids
vernacular_title: Vnekletochnyĭ kompartment épidermisa mlekopitaiushchikh.