Effect of exercise conditioning on red blood cell volume and erythropoietin concentration in the beagle dog.
To determine if endurance conditioning has a stimulating effect on red blood cell and erythropoietin production, we exercised five beagle dogs on a motor-driven treadmill for 1 hour per day, 5 days per week, for 6 weeks at a speed near their maximal capability. Three additional beagles were kept in cages and served as nonconditioned controls. Endurance conditioning in these dogs produced no increase in red blood cell mass, serum erythropoietin concentration, or any other blood cell index measured. We conclude that this type of exercise conditioning does not produce the necessary stimulus for an increase in erythropoiesis.
Mägerlein
H U
HU
Department of Anatomy and Physiology, Kansas State University, Manhattan 66506.
Heffner
S A
SA
Fedde
M R
MR
D000818:Animals; D004285:Dogs; D004911:Erythrocyte Volume / Q000502:physiology; D004921:Erythropoietin / Q000097:blood*; D005260:Female; D008297:Male; D010805:Physical Conditioning, Animal; D010807:Physical Endurance; D011863:Radioimmunoassay
D004921:Erythropoietin