Diabetic ulcers--a clinical and bacteriological study.
In an 8 month period we have studied 100 consecutive patients with diabetic ulcers. The sex distribution was even. Eighty-three percent had non-insulin dependent diabetes mellitus. Sixty-nine percent of the ulcers were gangrenous as opposed to neuropathic and over half the ulcers involved the big toes. Osteomyclitis was seen in 44% of the patients. Staphylococcus aureus and Escherichia coli were the commonest infecting organisms at initial cultures and at repeat cultures 4 weeks later. Amoxicillin plus clavulinic acid (Augmentin) and Clindamycin were the best antimicrobial combinations in cases where the ulcers had some acute features (e.g. surrounding cellulitis).
McLigeyo
College of Health Sciences, University of Nairobi, Department of Medicine, Kenya.
Oumah
S
S
Otieno
Saul
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L
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D048909:Diabetes Complications; D005260:Female; D005534:Foot Diseases / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D006225:Hand; D006801:Humans; D007630:Kenya / Q000453:epidemiology; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012883:Skin Ulcer / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology
D000900:Anti-Bacterial Agents