Involvement of corticospinal tract in Wilson's disease. A study of three cases with transcranial stimulation.
Muscle responses evoked by transcranial stimulation were studied in three patients with Wilson's disease. Abnormalities indicating involvement of corticospinal tract were demonstrated in one patient. In keeping with recent evoked potential studies, this finding suggests that lesions in Wilson's disease may affect structures other than the extrapyramidal system.
Berardelli
A
A
Department of Neurological Sciences, University of Rome, La Sapienza, Italy.
Inghilleri
M
M
Priori
A
A
Thompson
P D
PD
Fabri
S
S
Fieschi
C
C
Manfredi
M
M
D000293:Adolescent; D000328:Adult; D004558:Electric Stimulation; D005260:Female; D006527:Hepatolenticular Degeneration / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D008297:Male; D009119:Muscle Contraction / Q000502:physiology; D009132:Muscles / Q000294:innervation*; D010396:Penicillamine / Q000008:administration & dosage; D011712:Pyramidal Tracts / Q000503:physiopathology*; D011930:Reaction Time / Q000502:physiology; D014266:Trientine / Q000008:administration & dosage
D010396:Penicillamine; D014266:Trientine