[Cutaneous extramedullary hematopoiesis in idiopathic myelofibrosis. Description of a case].
The Authors present a case of cutaneous extramedullary hematopoiesis in a 63-year-old male patient with agnogenic myeloid metaplasia. The skin lesions appeared before splenectomy as multiple papules and nodules on the trunk. Histologic examination of a lesion showed all the tree components of the hematopoietic tissue, i.e. myeloid, erythroid and megakaryocytic series. A review of the literature revealed 18 previously reported cases, with polymorphous clinical manifestations of skin involvement. The possibility of extramedullary hematopoiesis should be considered in a patient with agnogenic myeloid metaplasia who shows cutaneous eruptions.
Del Forno
C
C
IRCCS Policlinico S. Matteo, Clinica Dermatologica, Università delgi Studi di Pavia.
Borroni
G
G
Caresana
G
G
Nalli
G
G
Barosi
G
G
D006410:Hematopoiesis; D006801:Humans; D008297:Male; D008533:Megakaryocytes; D008875:Middle Aged; D055728:Primary Myelofibrosis / Q000473:pathology*; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000473:pathology*
Ematopoiesi extramidollare cutanea in mielofibrosi idiopatica. Descrizione di un caso.