Sleep disturbance and computerized axial tomographic scan findings in former prisoners of war.
Ten drug-free former American prisoners of war (POWs), captured on Bataan and Corregidor by the Japanese in World War II, participated in a study of the relationship between structural brain abnormalities on computerized axial tomographic (CT) scans and sleep electroencephalographic (EEG) findings. All subjects had complaints of sleep disturbances and other posttraumatic stress disorder (PTSD)-related symptoms. Six of 10 subjects had no stage 4 sleep, and had significantly higher mean ventricular brain ratios (VBRs). Structural brain measures such as VBRs and global sulcal widening (GSW) correlated significantly with the number of awakenings; GSW also correlated significantly with time spent asleep. However, because data from normal age-matched controls are not available, it remains to be seen whether our findings are PTSD specific.
Peters
J
J
Veterans Affairs Medical Center, Pittsburgh, PA 15206.
van Kammen
D P
DP
van Kammen
W B
WB
Neylan
T
T
D000368:Aged; D001143:Arousal / Q000502:physiology; D001921:Brain / Q000473:pathology; D002552:Cerebral Ventricles / Q000473:pathology; D003130:Combat Disorders / Q000503:physiopathology / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000503:physiopathology / Q000523:psychology*; D011329:Prisoners / Q000523:psychology*; D012894:Sleep Stages / Q000502:physiology; D012893:Sleep Wake Disorders / Q000175:diagnosis* / Q000503:physiopathology; D014057:Tomography, X-Ray Computed; D014104:Torture; D014728:Veterans / Q000523:psychology*