[Two cases of Turner's syndrome with spondyloepiphyseal dysplasia like bone appearance].
We report two cases of mosaic karyotype (45XO/46XiXq) Turner's syndrome with unique bone appearance. The cases were 44 and 34 year-old women and latter was complicated by Hashimoto's thyroiditis (hypothyroidism). Following the systemic bone surveys, we found the patients showed not only osteoporotic bone change and short stature, but also spondyloepiphyseal dysplasia (SED) like bone appearance (thinness of vertebral bodies, irregularity of vertebral end-plates, shortness of femoral necks, Coxa valga, Coxa magna and hypoplasia of acetabula). Those findings can not be explained by degenerative bone changes like osteoporosis, rather are suggestive the sequelae of malgrowth of the bone system in Turner's syndrome.
Nakashima
N
N
Third Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka.
Suematsu
E
E
Takayanagi
R
R
Ohashi
M
M
Hotokebuchi
T
T
Nawata
H
H
D000328:Adult; D005260:Female; D006801:Humans; D010009:Osteochondrodysplasias / Q000209:etiology*; D014424:Turner Syndrome / Q000150:complications*