The wrinkly skin syndrome: a report of a case and review of the literature.
A 2 1/2-year-old boy born of Jewish Moroccan parents is reported with physical findings of wrinkled skin on the dorsum of the hands and feet, with poor skin elasticity, syndactyly, mild kyphosis and poor muscle tone, the diagnosis being the wrinkly skin syndrome. All reported cases of this heritable disorder of connective tissue are reviewed and discussed in terms of genetics, ethnic clustering and differential diagnosis.
Hurvitz
S A
SA
Department of Medical Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
Baumgarten
A
A
Goodman
R M
RM
D002675:Child, Preschool; D004535:Ehlers-Danlos Syndrome / Q000235:genetics*; D006801:Humans; D008297:Male; D015595:Skin Aging / Q000235:genetics*