Cell surface molecule A5: a putative involvement in retinal central connection.
We produced monoclonal antibodies against Xenopus tadpole visual centers and obtained an antibody named A5 (MAb-A5). The antigen of MAb-A5 is a cell-surface-related protein molecule (A5 antigen). Immunohistochemistry using MAb-A5 and an eye-transplantation experiment suggest the involvement of A5 antigen in specific cell recognition between retinal axons and their targets.
Fujisawa
H
H
Department of Anatomy, Kyoto Prefectural University of Medicine, Japan.
Takagi
S
S
Hirata
T
T
D000818:Animals; D000911:Antibodies, Monoclonal; D000954:Antigens, Surface / Q000276:immunology; D001921:Brain / Q000378:metabolism / Q000502:physiology*; D006825:Hybridomas / Q000166:cytology / Q000378:metabolism; D007814:Larva; D008565:Membrane Proteins / Q000276:immunology / Q000378:metabolism / Q000502:physiology*; D012160:Retina / Q000502:physiology*; D013997:Time Factors; D014018:Tissue Distribution; D014795:Visual Pathways / Q000254:growth & development / Q000293:injuries / Q000502:physiology*; D014981:Xenopus
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface; D008565:Membrane Proteins