Glucose 6-phosphate dehydrogenase deficiency and cataract of patients in northern Sardinia.
We determined the activity level of glucose 6-phosphate dehydrogenase in 467 patients with cataract from northern Sardinia. Of 226 men, 18 (8%) had glucose 6-phosphate dehydrogenase deficiency. Of 241 women, 30 (12%) were heterozygous and two (1%) were homozygous for glucose 6-phosphate dehydrogenase deficiency. These prevalences were not significantly different from those expected in the general population. We concluded that patients with glucose 6-phosphate dehydrogenase deficiency do not have a higher risk of developing cataract.
Meloni
T
T
Clinica Pediatrica A. Filia, Università di Sassari, Italy.
Carta
F
F
Forteleoni
G
G
Carta
A
A
Ena
F
F
Meloni
G F
GF
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D002386:Cataract / Q000150:complications* / Q000453:epidemiology; D005260:Female; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000150:complications* / Q000453:epidemiology / Q000235:genetics; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D015995:Prevalence