Removal of radiation-induced cataracts in patients treated for retinoblastoma.
Experience with removal of radiation-induced cataract in patients treated for retinoblastoma is limited. We retrospectively reviewed the records of 38 patients with retinoblastoma (42 eyes) who underwent removal of radiation-induced cataract from 1973 to 1989. Nineteen eyes (45%) without macular tumors or severe radiation complications had final visual acuities in the range of 20/20 to 20/50. One eye (2.4%) developed a rhegmatogenous retinal detachment and four eyes (9.5%) were noted to have amblyopia after cataract removal. Three eyes (7%) developed retinoblastoma recurrence, one with extension of retinoblastoma into the subconjunctival space through the previous sclerotomy. Exenteration was performed and the patient was alive after 8 years. Cataract removal can be visually beneficial in selected patients with radiation-induced cataracts.
Brooks
H L
HL
Vitreoretinal Service, Tallahassee, Fla.
Meyer
D
D
Shields
J A
JA
Balas
A G
AG
Nelson
L B
LB
Fontanesi
J
J
D000293:Adolescent; D002386:Cataract / Q000209:etiology*; D002387:Cataract Extraction / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D003315:Cornea / Q000601:surgery; D005134:Eye Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D007223:Infant; D007908:Lens, Crystalline / Q000601:surgery; D008297:Male; D009364:Neoplasm Recurrence, Local; D011184:Postoperative Period; D011832:Radiation Injuries; D012175:Retinoblastoma / Q000473:pathology / Q000532:radiotherapy*; D012189:Retrospective Studies; D014792:Visual Acuity; D014821:Vitrectomy