Serum uric acid correlates in elderly men and women with special reference to body composition and dietary intake (Dutch Nutrition Surveillance System).
In 460 apparently healthy Dutch elderly, aged 65-79 years, serum uric acid correlates were studied by linear regression analyses, for men and women separately. Diuretic therapy, total serum cholesterol (women only) and creatinine clearance (in bivariate analysis only) were significantly associated with serum uric acid level. Positive associations of serum uric acid with body weight, body mass index, body fatness (men) and lean body mass (men) were observed, with and without adjustment for diuretic therapy, creatinine clearance and age. Serum uric acid levels, whether adjusted or not for these variables and for body mass index, were positively associated with alcohol intake (men) and consumption of meat and fish (women), and inversely with consumption of bread, margarine and milk products (women). These results indicate that limited medication with diuretics, weight control and restriction of alcohol use may help to prevent hyperuricemia in the elderly.
Loenen
H M
HM
Department of Environmental and Tropical Health, Agricultural University, Wageningen, The Netherlands.
Eshuis
H
H
Löwik
M R
MR
Schouten
E G
EG
Hulshof
K F
KF
Odink
J
J
Kok
F J
FJ
D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects; D000886:Anthropometry; D000959:Antihypertensive Agents / Q000009:adverse effects; D015992:Body Mass Index; D001835:Body Weight; D004032:Diet; D004232:Diuretics / Q000009:adverse effects; D005260:Female; D015577:Geriatric Assessment; D006073:Gout / Q000097:blood / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications; D008019:Life Style; D008297:Male; D009426:Netherlands / Q000453:epidemiology; D009749:Nutrition Surveys; D009765:Obesity / Q000150:complications; D011159:Population Surveillance; D015995:Prevalence; D012307:Risk Factors; D014527:Uric Acid / Q000097:blood*
D000959:Antihypertensive Agents; D004232:Diuretics; D014527:Uric Acid