Comparison of four local extradural anaesthetic solutions for elective caesarean section.
We have examined a combination of two local anaesthetics to see if the resultant solution is superior to the agents individually. This study shows that a mixture of bupivacaine and lignocaine provided an excellent alternative to bupivacaine alone, and was superior to 2% lignocaine with adrenaline for elective Caesarean section. By reducing the dose of bupivacaine used, the combination may reduce the risk of cardiotoxicity.
Howell
P
P
Queen Charlotte's and Chelsea Hospital, London.
Davies
W
W
Wrigley
M
M
Tan
P
P
Morgan
B
B
D000328:Adult; D000767:Anesthesia, Epidural / Q000379:methods*; D000773:Anesthesia, Obstetrical / Q000379:methods*; D000779:Anesthetics, Local; D002045:Bupivacaine; D002585:Cesarean Section; D004338:Drug Combinations; D004837:Epinephrine; D005260:Female; D006801:Humans; D008012:Lidocaine; D011247:Pregnancy; D013997:Time Factors
D000779:Anesthetics, Local; D004338:Drug Combinations; D008012:Lidocaine; D002045:Bupivacaine; D004837:Epinephrine