[Correlation between the lymphocyte surface potential and membrane potential in various physiological states].
Present work shows that changes in the surface potential (SP) are linearly connected with alterations of the cell membrane potential (MP) at three physiological states of the organism: control (C), induced cancerogenesis (IC) and total reaction of the organism to damage (TRD). In the control greater SP changes are corresponded with the least MP changes. When SP is changed almost by 100%, MP change is about 20%. In the course of TRD development a reverse relationship is observed: 20% change of the charge is corresponded by a practically 100% change of MP. The relationship indices of MP and SP change in the course of TRD and in the control are equal: with a decrease of MP the lymphocyte SP is also decreased. At the initial stages of IC development the relationship index of MP with SP is changed. In this case a 20% decrease of SP is accompanied by a 60% increase of MP.
Gorkin
P N
PN
Zatsepina
G N
GN
Tarasova
I M
IM
D000817:Anilino Naphthalenesulfonates; D000818:Animals; D002478:Cells, Cultured; D005456:Fluorescent Dyes; D008214:Lymphocytes / Q000502:physiology*; D008564:Membrane Potentials; D051379:Mice; D008805:Mice, Inbred A; D009369:Neoplasms / Q000139:chemically induced / Q000503:physiopathology*; D014947:Wounds and Injuries / Q000503:physiopathology*
D000817:Anilino Naphthalenesulfonates; D005456:Fluorescent Dyes
Korreliatsii mezhdu potentsialom poverkhnosti limfotsitov i membrannym potentsialom v fiziologicheski razlichnykh sostoianiiakh organizma.