Age-related changes in evoked otoacoustic emissions.
Outer hair cells of the organ of Corti play an important part in the genesis of evoked otoacoustic emissions (EOAEs), which are related to cochlear biomechanics. The aim of this study was to investigate the age factor in relation to EOAEs in 166 ears of subjects between 6 weeks and 83 years of age. The results show that when age increases, the presence of EOAEs by age group and the frequency peak in spectral analysis decrease, and EOAE threshold increases. Thus, there is an effect of age upon EOAEs, and it seems linked with alteration of cochlear biomechanics and/or hair cell loss. Such an effect has to be taken into consideration when EOAEs are used in clinical applications, and limits the use of EOAEs in older subjects.
Collet
L
L
Laboratoire d'Explorations Fonctionnelles Neurosensorielles, Hôpital Edouard Herriot, Lyon, France.
Moulin
A
A
Gartner
M
M
Morgon
A
A
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000473:pathology / Q000502:physiology*; D001309:Auditory Threshold / Q000502:physiology; D001696:Biomechanical Phenomena; D002648:Child; D002675:Child, Preschool; D003051:Cochlea / Q000502:physiology; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged