Parkinsonian tremor loses its alternating aspect during non-REM sleep and is inhibited by REM sleep.
Non-REM sleep transforms the waking alternating Parkinsonian tremor into subclinical repetitive muscle contractions whose amplitude and duration decrease as non-REM sleep progresses from stages I to IV. During REM sleep Parkinsonian tremor disappears while the isolated muscle events increase significantly.
Askenasy
J J
JJ
Department of Neurology, Sackler School of Medicine, Tel-Aviv University, Israel.
Yahr
M D
MD
D000328:Adult; D000368:Aged; D001143:Arousal / Q000502:physiology; D001931:Brain Mapping; D004576:Electromyography; D005071:Evoked Potentials / Q000502:physiology; D005116:Extrapyramidal Tracts / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction / Q000502:physiology; D009132:Muscles / Q000294:innervation; D009433:Neural Inhibition / Q000502:physiology*; D010300:Parkinson Disease / Q000503:physiopathology*; D012894:Sleep Stages / Q000502:physiology*; D012895:Sleep, REM / Q000502:physiology*; D014202:Tremor / Q000503:physiopathology*