[Neutrophils do not affect clonal growth of granulocyte progenitor cells cultured in vivo in diffuse chambers].
The effect of polymorphonuclear leukocytes on the growth of granulocytic progenitors in the diffusion chamber culture (CFU-dG) has been studied. It has been shown that peripheral blood neutrophils do not affect the myeloid colony formation in this culture system. The inhibition of CFU-dG growth, observed in the presence of peripheral blood leukocytes was dependent on prostaglandins release from monocytes.
Hansz
J
J
Kliniki Hematologii Instytutu Chorób Wewnetrznych Akademii Medycznej w Poznaniu.
Wozny
T
T
Jurkowiecka
J
J
Sawiński
K
K
Mensah
O W
OW
D000818:Animals; D002455:Cell Division / Q000502:physiology; D002478:Cells, Cultured; D003114:Colony-Forming Units Assay; D015194:Diffusion Chambers, Culture / Q000379:methods; D005260:Female; D006098:Granulocytes / Q000166:cytology*; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D006801:Humans; D009504:Neutrophils / Q000502:physiology*; D010529:Peritoneal Cavity; D051381:Rats; D011919:Rats, Inbred Strains
Granulocyty obojetnochłonne nie wpływaja na wzrost klonalny komórek ukierunkowanych szeregu granulocytarnego w hodowli w komorach dyfuzyjnych in vivo.