[The characteristics of the immune response to Chlamydia antigens in patients with Reiter's disease].
Immunologic tests (complement fixation, microprecipitation reaction, leukocytic agglomeration phenomenon, leukocyte migration inhibition tests) with standard chlamydial antigen were used in examinations of 116 male patients with Reiter's disease, 54 of these with the first (early) and 62 with the second (late) stages of this process. The findings evidence a higher intensity of antichlamydial humoral and cellular immune response in the patients with the first stage of the disease and a much lower intensity of those with the second stage. The pathologic process in patients with the second stage is liable to a prolonged self-maintaining course and is torpid to anti-infection therapy, as against that in the patients with the first stage of the condition; this fact prompts a conclusion that such a course of the process is explained not so much by the infectious agent, as by immune inflammation.
Kovalev
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IuN
D000907:Antibodies, Bacterial / Q000097:blood; D000917:Antibody Formation / Q000276:immunology; D000937:Antigen-Antibody Reactions / Q000276:immunology*; D000942:Antigens, Bacterial / Q000276:immunology*; D016918:Arthritis, Reactive / Q000276:immunology*; D002689:Chlamydia / Q000276:immunology*; D002908:Chronic Disease; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology; D008297:Male; D013997:Time Factors
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial
Osobennosti immunnogo otveta na antigeny khlamidiĭ bol'nykh bolezn'iu Reĭtera.