title: Studies on the stage of action of lasalocid against Eimeria tenella and Eimeria acervulina in the chicken.
abstract: Broiler chickens in battery pens were either fed a diet containing 100 ppm lasalocid or no drug for 24 h prior to inoculation with sporulated oocysts of Eimeria tenella or Eimeria acervulina. Different groups of birds remained on medicated feed for 24, 48, 72, 96, 120 or 144 h after inoculation. Conversely, other groups started on an unmedicated diet, were given medicated feed at different times after oocyst inoculation. Starting lasalocid medication 24 h (E. tenella) or 48 h (E. acervulina) after inoculation reduced the lesions and improved the weight gain. There was no significant difference in performance of birds after withdrawal of the drug at 48 h (E. tenella) or 72 h (E. acervulina) and thereafter. Starting lasalocid medication at 96 or 120 h did not suppress but rather reduced oocyst production.
authors: Department of Poultry Science, University of Georgia, Athens 30602.
authors: V
authors: V
authors: Guyonnet
authors: J K
authors: JK
authors: Johnson
authors: P L
authors: PL
authors: Long
mesh_terms: D000818:Animals; D002645:Chickens / Q000469:parasitology*; D003048:Coccidiosis / Q000188:drug therapy / Q000662:veterinary*; D004539:Eimeria / Q000187:drug effects*; D007832:Lasalocid / Q000494:pharmacology / Q000627:therapeutic use*; D011201:Poultry Diseases / Q000188:drug therapy*; D015430:Weight Gain
chemical_list: D007832:Lasalocid