[Inhibition of caries by Na-saccharin].
The inhibition of dental caries by Na-saccharin was studied in an optimized and standardized experiment with cara rats. The animals were given a cariogenic diet ad libitum as well as under controlled frequency feeding conditions. The addition of 0.5% Na-saccharin to the cariogenic diet produced no cariostatic effects. Ancilliary microbiological in vitro and in vivo experiments showed no appreciable bacteriostatic effects on the cariogenic bacteria flora.
Karle
E J
EJ
Universität Wurzburg.
Gehring
F
F
D000818:Animals; D003731:Dental Caries / Q000517:prevention & control*; D003773:Dental Plaque / Q000382:microbiology*; D004037:Diet, Cariogenic; D051381:Rats; D012439:Saccharin / Q000378:metabolism*
D012439:Saccharin
Zur kariostatischen Wirkung von Na-Saccharin.