title: [Development of 62 typical carcinoid tumor of the bronchi surgically treated. Prognostic value of histopathological features].
abstract: The pathological and clinical features of 62 carcinoid tumours of the bronchus operated between 1975 and 1987 were reviewed in order to determine the prognostic value of certain parameters: limit of proliferation, vascular invasion, lymph node involvement. This series corresponded to 36 central tumours and 25 peripheral tumours, all treated surgically. One patient was lost to follow-up, 3 developed recurrences, 56 are still alive without recurrence and 3 died from intercurrent causes. The histological appearance of the tumours was homogeneous and typical. Twenty-eight lesions were strictly intrabronchial, 34 invaded the lung with incomplete limits in twenty cases. The tumour showed signs of vascular invasion in ten cases and the adjacent lymph nodes were invaded in eight cases. The local recurrence was undoubtedly related to an excessively conservative primary resection, as the primary tumour did not demonstrate any unusual features. The two tumours which metastasized showed vascular invasion: one metastasized to a hilar node, but these features were observed in other cases which retained a benign course. The standard histological diagnosis of typical carcinoid tumour does not appear to raise any particular difficulties; it is reliable. The course of the disease is sometimes malignant but no histological parameter is able to accurately predict this outcome.
authors: Service de Chirurgie Thoracique, CHU de Strasbourg.
authors: N
authors: N
authors: Roeslin
authors: B
authors: B
authors: Gasser
authors: E
authors: E
authors: Popin
authors: A
authors: A
authors: Warter
authors: J M
authors: JM
authors: Wihlm
authors: G
authors: G
authors: Morand
authors: J P
authors: JP
authors: Witz
mesh_terms: D000328:Adult; D001984:Bronchial Neoplasms / Q000473:pathology* / Q000601:surgery; D002276:Carcinoid Tumor / Q000473:pathology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate
vernacular_title: Evolution de soixante-deux tumeurs carcinoïdes typiques des bronches opérées. Valeur pronostique des caractères histopathologiques.