Spectrophotometric determination of bismuth in pharmaceutical preparations using 1-[di(2-pyridyl)--methylene]-5-salicylidene-thiocarbonohydrazide.
A simple and fast spectrophotometric method for the determination of bismuth in pharmaceutical preparations is described. The used chromatic reactive is 1-[di(2-pyridyl)methylene]-5-salicilydene-thiocarbonohydrazide+ ++ forming a yellow complex with bismuth. In a solution containing 40% v/v of dimethylformamide molar absorption is 5.7 x 10(4) l.mol-1.cm-1 at 421 nm and at pH 4.3. The optimal conditions for the color development and the possible interferences are studied.
Morales
M T
MT
Department of Analytical Chemistry, Faculty of Pharmacy, University of Seville, Spain.
Montaña
M T
MT
Galan
G
G
Gomez Ariza
J L
JL
D001729:Bismuth / Q000032:analysis*; D055598:Chemical Phenomena; D002621:Chemistry; D004126:Dimethylformamide / Q000032:analysis; D006834:Hydrazines; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents; D011725:Pyridines; D013053:Spectrophotometry
D006834:Hydrazines; D007202:Indicators and Reagents; D011725:Pyridines; C066715:1-(di-(2-pyridyl)methylene)-5-salicylidenethiocarbonohydrazide; D004126:Dimethylformamide; D001729:Bismuth