title: Loop diathermy excision of the cervical transformation zone in patients with abnormal cervical smears.
abstract: OBJECTIVE
  To determine the efficacy and morbidity of fine loop diathermy excision of the cervical transformation zone as applied to the management of outpatients with abnormal cervical smears.
  
  
  METHODS
  Prospective programme trial with six month follow up.
  
  
  METHODS
  Two hospital based colposcopy clinics.
  
  
  METHODS
  616 Patients aged 16-60 with abnormal cervical smears.
  
  
  METHODS
  After colposcopic and cytological assessment excision of the cervical transformation zone by fine loop diathermy under local anaesthesia in the outpatient department.
  
  
  METHODS
  Time to complete the treatment, immediate morbidity in terms of discomfort and bleeding, and cytological and colposcopic findings at six months.
  
  
  RESULTS
  Treatment was completed in a mean of 3.47 minutes (SD 1.99). Immediate morbidity was minimal, and histological specimens were adequate in over 90% of cases. Almost two thirds of patients were treated at their first visit to the clinic. 58 Patients (9.4%) failed to attend for follow up at six months and one had had a hysterectomy. Of the 557 patients who attended for colposcopic and cytological follow up at six months, 506 (91%) were normal cytologically and 19 (3.4%) had histologically confirmed persistence of cervical intraepithelial neoplasia. The overall confirmed failure rate of the technique was 4.4%.
  
  
  CONCLUSIONS
  Loop diathermy excision is an effective treatment with low morbidity and is an appropriate modality for patients with abnormal cervical smears.
authors: Department of Obstetrics and Gynaecology, University of Birmingham.
authors: D M
authors: DM
authors: Luesley
authors: J
authors: J
authors: Cullimore
authors: C W
authors: CW
authors: Redman
authors: F G
authors: FG
authors: Lawton
authors: J M
authors: JM
authors: Emens
authors: T P
authors: TP
authors: Rollason
authors: D R
authors: DR
authors: Williams
authors: E J
authors: EJ
authors: Buxton
mesh_terms: D000293:Adolescent; D000328:Adult; D002584:Cervix Uteri / Q000473:pathology; D003127:Colposcopy; D004564:Electrocoagulation; D005260:Female; D006801:Humans; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*; D014626:Vaginal Smears