[An analysis of the antigenic structure of the hemagglutinins from different strains of the influenza B virus by using monoclonal antibodies].
A comparative immunological analysis of the antigenic composition of hemagglutinin (HA) of influenza B virus drift-variants isolated during 46 years was carried out using monoclonal antibodies (MAb) to HA of B/Oregon 5/80 virus in HI test and solid-phase enzyme immunoassay. The presence of type- and group-specific antigenic determinants was demonstrated which agreed with our previous data obtained in studies with polyvalent sera. However, using Mab three more group-specific determinants were detected which characterize HA of influenza B viruses isolated in 1970-1979, 1970-1984, and 1970-1986.
Platonova
A L
AL
Rovnova
Z I
ZI
Podcherniaeva
R Ia
RIa
D000911:Antibodies, Monoclonal; D000940:Antigenic Variation / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D006385:Hemagglutination Inhibition Tests; D006389:Hemagglutinins, Viral / Q000032:analysis / Q000276:immunology*; D009981:Influenza B virus / Q000276:immunology*; D013997:Time Factors
D000911:Antibodies, Monoclonal; D006389:Hemagglutinins, Viral
Analiz antigennoĭ struktury gemaggliutininov razlichnykh shtammov virusa B s pomoshch'iu monoklonal'nykh antitel.