[The determination of the activity of natural killer cells in chronic lympholeukemia based on radiometric and morphological data].
Function of lymphocytes as effector cells of natural cytotoxicity in chronic lympholeukemia was investigated using radiometric and morphological methods. The effectiveness of these methods was compared. A significant decrease in NKC activity in B-cell type of chronic lympholeukemia was detected. A high degree of positive correlation between radiometry and morphology findings was revealed. The radionuclide (51Cr) method of investigation of NKC activity of lymphocytes was shown to have more advantages over the alternative morphological method in terms of practicability, accuracy and objectiveness.
Sivachenko
T P
TP
Fed'ko
A A
AA
Guseva
S A
SA
D000328:Adult; D000368:Aged; D002860:Chromium Radioisotopes; D003601:Cytotoxicity Tests, Immunologic / Q000379:methods; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007694:Killer Cells, Natural / Q000000981:diagnostic imaging / Q000276:immunology* / Q000473:pathology; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000000981:diagnostic imaging / Q000276:immunology* / Q000473:pathology; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D012397:Rosette Formation
D002860:Chromium Radioisotopes
Opredelenie aktivnosti estestvennykh kletok-killerov pri khronicheskom limfoleĭkoze po dannym radiometricheskogo i morfologicheskogo metodov.