[Necrobiosis lipoidica diabeticorum in children. Description of a case].
A case of necrobiosis lipoidica diabeticorum (NLD) in a 12-year-old male patient is described. Diabetes mellitus (DM) was diagnosed at the age of 1.5 years. The onset of the first NLD lesion had been previously observed at the age of 7, on the back of the left foot. Three new lesions appeared at the age of 8, one on the left leg, the others on the thighs. At the age of 12, four infiltrated, reddish patches, with slight central atrophy were evident on his lower extremities. Histopathological features showed foci of collagen degeneration with sclerosis, surrounded by a chronic, mainly perivascular, granulomatous infiltrate, made up of lymphocytes and histiocytes. The patient is now 19-year old, with no eye or kidney failure, owing to a constant metabolic control of DM. A constant follow-up of the patient demonstrated a self-resolution of NLD plaques, with no evidence of further lesions.
Zaccone
C
C
Dipartimento di Patologia Umana ed Ereditaria, Università di Pavia.
Vignoli
G P
GP
Vignati
G
G
Borroni
G
G
D002648:Child; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009335:Necrobiosis Lipoidica / Q000473:pathology; D011379:Prognosis; D012867:Skin / Q000473:pathology; D013997:Time Factors
Necrobiosis lipoidica diabeticorum nel bambino. Descrizione di un caso.