title: [Clinical characteristics of 153 patients with Crohn's disease. Presentation of a Turin case series].
abstract: This clinical and epidemiological retrospective study of 153 Italian Crohn's disease patients, surveyed between 1965 and 1988 took into account the following features: male to female ratio; region of origin; familiarity; age at onset; anatomical site of lesions; symptoms at onset; diagnostic delay; local and general complications; relapses; admissions; surgery and mortality rates. The clinical patterns of 67 patients surveyed between 1965 and 1977 (group A) were compared with those of 86 patients observed from 1978 to 1988 (group B). Overall results agreed with those of the literature, except for a male prevalence and a longer diagnostic delay. As compared to group A, group B showed: a) a higher number of females; b) a statistically significant increase (p less than 0.001) of patients from Southern Italy, thus supporting the hypothesis of a role of environmental factors in the onset of the disease; c) a reduced surgery rate, in agreement with the general trend of a more cautious surgical approach in Crohn's disease.
authors: Dipartimento di Fisiopatologia clinica, Università, Torino.
authors: C
authors: C
authors: Sategna-Guidetti
authors: E
authors: E
authors: Marucco
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003424:Crohn Disease / Q000453:epidemiology* / Q000401:mortality / Q000601:surgery; D005260:Female; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D012737:Sex Factors
vernacular_title: Caratteristiche cliniche di 153 pazienti affetti da malattia di Crohn. Presentazione di una casistica torinese.