[Comparative study of the tumor regression rate of 127 uveal melanomas irradiated with 106 Ru/106 Rh. Attempted analysis of the correlations between per-operative cytology and histopathology of the enucleated eye and the tumoral regression on the one hand, and general prognosis on the other hand].
A study of the speed of tumor regression in 127 uveal melanomas treated with beta-rays brachyterapy, since June 1983, allows a division into 2 groups: radiosensitive forms with a volume less than 50% in the following year, and radioresistant forms. Correlation between radio sensitivity and tumor cell type were obtained with intraoperative cytopunction, and showed the prevalence of epithelioid type. The results of enucleation indicate the prevalence of fusiform type inside the radioresistant tumor group. No precise correlation could be brought between death and the previous data, the most important negative criteria being the level of initial tumor height equal or superior to 7 mm.
Grange
J D
JD
Clinique Ophtalmologique Universitaire B, Hôpital Croix-Rousse, Lyon.
Thacoor
S
S
Bievelez
B
B
Jean-Louis
B
B
Baute
B
B
Gérard
J P
JP
Sentenac
I
I
Fontanière
B
B
Bailly
C
C
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy; D002830:Choroid Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D002924:Ciliary Body; D015353:Eye Enucleation; D006801:Humans; D008545:Melanoma / Q000473:pathology / Q000532:radiotherapy*; D008875:Middle Aged; D011379:Prognosis; D012074:Remission Induction; D013997:Time Factors; D014604:Uveal Neoplasms / Q000473:pathology / Q000532:radiotherapy*
Etude comparative de la vitesse de régression tumorale de 127 mélanomes uvéaux irradiés par 106 RU/106 RH. Essai d'analyse des corrélations entre la cytologie per-opératoire, l'histophathologie des globes énucléés et la régression tumorale d'une part, le pronostic général d'autre part.