[The adhesion of clinical isolates of Campylobacter jejuni to intestinal epithelial cells in vitro].
The adhesive activity of C. jejuni isolated from feces of children with Campylobacter infection was studied with the use of a newly developed model. 47 clinical isolates were analyzed; of these, 91% were found to be enteroadhesive to a variable degree. As the result of in vitro studies, Campylobacter were found to have much greater tropism to colonic cells and epithelial cells of Peyer's patches in comparison with the epithelial cells of the small intestine. The correlation between the degree of adhesive activity and the severity of the course of Campylobacter infection in children.
Gorelov
A V
AV
Gorskaia
E M
EM
Zhukhovitskiĭ
V G
VG
Bondarenko
V M
VM
D000208:Acute Disease; D000293:Adolescent; D000818:Animals; D001422:Bacterial Adhesion; D016123:Campylobacter jejuni / Q000302:isolation & purification / Q000472:pathogenicity*; D002478:Cells, Cultured / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D004848:Epithelium / Q000382:microbiology; D005243:Feces / Q000382:microbiology; D006801:Humans; D007223:Infant; D007410:Intestinal Diseases / Q000382:microbiology; D007422:Intestines / Q000382:microbiology*; D051381:Rats; D011919:Rats, Inbred Strains
Adgeziia klinicheskikh izoliatov Campylobacter jejuni k épitelial'nym kletkam kishechnika in vitro.