[The characteristics of the synaptic reorganization in the sensorimotor cortex of cats after the destruction of the symmetrical portion of the cortex in the opposite hemisphere].
Intracellular recording technique has been used to study reactions of corticospinal neurons (CSN) to stimulation of the ipsilateral ventrolateral nucleus (VLN) of the thalamus in acute experiments on adult intact cats and on cats after lesion on the contralateral sensorimotor cortex (exposition from 6 months to 1.5 years). Acceleration of the monosynaptic EPSPs rise phase in slow CSN was revealed in operated animals, which presumed the reorganization of the synaptic contacts in the SD membrane of flow CSN. Detailed analysis of features and branching of CSN axon, collaterals passing to VLN of the thalamus and participating in formation of the ipsilateral pyramidal tract was made by the method of collision test. The significance of the plastic synaptic reconstruction in the ipsilateral thalamo-cortex reverberating system during the outflow formation under conditions of the partial cortex interhemisphere deafferentation is discussed.
Sarkisian
D S
DS
Tsakanian
K V
KV
Metsoian
N A
NA
D000818:Animals; D001369:Axons / Q000502:physiology; D002415:Cats; D004292:Dominance, Cerebral / Q000502:physiology*; D004558:Electric Stimulation / Q000379:methods; D005071:Evoked Potentials / Q000502:physiology; D009044:Motor Cortex / Q000502:physiology*; D009474:Neurons / Q000502:physiology; D011712:Pyramidal Tracts / Q000502:physiology; D013569:Synapses / Q000502:physiology*; D013787:Thalamic Nuclei / Q000502:physiology
Osobennosti sinapticheskoĭ reorganizatsii v sensomotornoĭ kore mozga u koshek posle razrusheniia simmetrichnogo otdela kory protivopolozhnogo polushariia.