[The pharmacologic and biochemical effects of unsaturated phospholipids].
The review deals with the analysis of the recent publications indicating the important biological function of essential phospholopids (EP) in the cell and in the organism as a whole. The protective mechanism of action of EP in diseases of the liver, atherosclerosis, ischemic heart disease, myocardial infarction determined by their high biological activity in some pathological conditions associated with lipid metabolism disturbance is discussed. The efficiency of the biological action of EP is determined by the depends on the type of phospholipids, the form of phospholipid preparations, their charge, and also on the routes of their administration.
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D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000188:drug therapy / Q000378:metabolism; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy / Q000378:metabolism; D004337:Drug Carriers; D006801:Humans; D008081:Liposomes; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D010742:Phospholipid Ethers / Q000493:pharmacokinetics / Q000494:pharmacology* / Q000627:therapeutic use; D010743:Phospholipids / Q000378:metabolism
D004337:Drug Carriers; D008081:Liposomes; D010742:Phospholipid Ethers; D010743:Phospholipids
Farmakologicheskie i biokhimicheskie éffekty nenasyshchennykh fosfolipidov.