title: [An immunoenzyme system for determining antibodies to Streptococcus pneumoniae polysaccharides in biological fluids].
abstract: The enzyme immunoassay (EIA) system for the determination of antibodies to capsular polysaccharides of pneumococci, serotypes 1, 3, 6B, 8, 9N, 15F, 23F, and C-polysaccharide has been developed on the basis of poly-L-lysin-modified antigens. The use of isotype-specific conjugates in this system permits the detection of IgG and IgA antibodies in different biological fluids: blood serum, pleural fluid, saliva, milk. Samples obtained from children with pneumococcal infection and from nursing mothers have been studied. As shown in this study, the EIA system can be used for the evaluation of the dynamics of pneumococcal infection in children.
authors: L N
authors: LN
authors: Padiukov
authors: M A
authors: MA
authors: Ulanova
authors: E M
authors: EM
authors: Kuznetsova
authors: M K
authors: MK
authors: Ksenofontova
authors: Iu V
authors: IuV
authors: Kulak
authors: M Kh
authors: MKh
authors: Sharapova
authors: A P
authors: AP
authors: Baturo
mesh_terms: D000293:Adolescent; D000907:Antibodies, Bacterial / Q000032:analysis*; D001826:Body Fluids / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006801:Humans; D007223:Infant; D008895:Milk, Human / Q000276:immunology; D011018:Pneumonia, Pneumococcal / Q000276:immunology; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D013296:Streptococcus pneumoniae / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial; D011135:Polysaccharides, Bacterial
vernacular_title: Immunofermentnaia sistema dlia opredeleniia antitel k polisakharidam Streptococcus pneumoniae v biologicheskikh zhidkostiakh.