[The distribution of kainate and quisqualate receptors in the rat cerebellum].
Sensitivity of isolated Purkinje neurons from rat cerebellum to agonists of excitatory amino acids was studied. Kainate and quisqualate activated inward currents in the most studied neurons. NMDA and APB were ineffective. Distribution of kainate and quisqualate receptors was different. Currents activated by kainate and quisqualate were not additive. Hypotheses allowing one to explain the observed results were discussed.
Marchenko
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SM
D000613:Aminobutyrates / Q000494:pharmacology; D000818:Animals; D002478:Cells, Cultured / Q000187:drug effects / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D007608:Kainic Acid / Q000494:pharmacology*; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D016202:N-Methylaspartate / Q000494:pharmacology; D011689:Purkinje Cells / Q000187:drug effects* / Q000502:physiology; D016318:Quisqualic Acid / Q000494:pharmacology*; D051381:Rats; D011955:Receptors, Drug / Q000187:drug effects* / Q000502:physiology
D000613:Aminobutyrates; D011955:Receptors, Drug; D016202:N-Methylaspartate; D016318:Quisqualic Acid; C012729:2-amino-4-phosphonobutyric acid; D007608:Kainic Acid
Raspredelenie retseptorov kainata i kviskvalata v neĭronakh mozzhechka krysy.