[Adenylate cyclase activity of the plasma membranes of lung tissue at lengthy periods following non-lethal gamma-irradiation of rats].
Basal and stimulated activity of adenylate cyclase (cyclizing ATP-pyrophosphate lyase, E.C. 4.6.1.1., AC) in plasma membranes of pulmonary tissue was being studied during a year after fractionated irradiation of rats (2 GyX3). Basal and hormone-stimulated activity of AC was shown to vary significantly from normal 6 and 12 months after irradiation. The exposed membranes responded differently to AC activation by isoproterenol and F-.
Slozhenikina
L V
LV
Ruda
V P
VP
Ushakova
T E
TE
Kuzin
A M
AM
D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D002462:Cell Membrane / Q000201:enzymology* / Q000528:radiation effects; D003037:Cobalt Radioisotopes; D005260:Female; D005461:Fluorine / Q000494:pharmacology; D005720:Gamma Rays; D008168:Lung / Q000166:cytology* / Q000201:enzymology / Q000528:radiation effects; D008297:Male; D011833:Radiation Injuries, Experimental / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains; D013268:Stimulation, Chemical; D013997:Time Factors
D003037:Cobalt Radioisotopes; D005461:Fluorine; D000262:Adenylyl Cyclases
Aktivnost' adenilattsiklazy plasmaticheskikh membran legochnoĭ tkani v otdalennye sroki posle neletal'nogo gamma-oblucheniia krys.