[Radioprotective properties of ubiquinones during acute and chronic irradiation of rats].
Protective and therapeutic effect of ubiquinone-8 was demonstrated on rats exposed to 8 Gy radiation. There was a 16-20% increase in the survival rate of the irradiated rats as compared with the controls. The per os administration of ubiquinone-8 during a five-month period in conditions of chronic exposure arrested the radiation-induced accumulation of lipids in rat liver and somewhat improved the dynamics of the body mass growth in the exposed rats.
Novoselova
E G
EG
Kolomiĭtseva
I K
IK
Korsunskiĭ
O F
OF
Obol'nikova
E A
EA
Samokhvalov
G I
GI
Kogan
A M
AM
Mozgovoĭ
E G
EG
Kuzin
A M
AM
D000208:Acute Disease; D000284:Administration, Oral; D000818:Animals; D002908:Chronic Disease; D003037:Cobalt Radioisotopes; D005720:Gamma Rays; D007279:Injections, Subcutaneous; D008297:Male; D011833:Radiation Injuries, Experimental / Q000188:drug therapy* / Q000401:mortality / Q000517:prevention & control; D011837:Radiation-Protective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D051381:Rats; D011919:Rats, Inbred Strains; D014451:Ubiquinone / Q000008:administration & dosage / Q000627:therapeutic use*
D003037:Cobalt Radioisotopes; D011837:Radiation-Protective Agents; D014451:Ubiquinone; C030778:ubiquinone 8
Radioprotektornye svoĭstva ubikhinonov pri ostroĭ i khronicheskom obluchenii krys.