title: Ivermectin and coagulation: an in vitro study.
abstract: The prothrombin time, partial thromboplastin time with kaolin, and thrombin clotting time of plasma derived from healthy human volunteers were unaltered after in vitro addition of therapeutic concentrations (20-90 ng ml-1) of ivermectin. No difference in these coagulation tests, relative to untreated controls, was observed after 12 hours' incubation with the drug.
authors: School of Pharmacy, Leicester Polytechnic.
authors: J
authors: J
authors: Hay
authors: M A
authors: MA
authors: Arnott
mesh_terms: D000328:Adult; D001777:Blood Coagulation / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D066298:In Vitro Techniques; D007559:Ivermectin / Q000494:pharmacology*; D008297:Male; D010314:Partial Thromboplastin Time; D011517:Prothrombin Time; D013918:Thrombin Time; D013997:Time Factors
chemical_list: D007559:Ivermectin