[Antineoplastic activity of combinations of cytostatics and dextran-ferrite administered to mice with leukemia P-388].
Water solutions of adriblastin, dactinomycin, rosevin, methotrexate, cisplatin, sarcolysine, rubomycin, cyclophosphamide, 5-fluorouracil or ftorafur were combined with dextran ferrite. The obtained compositions were injected i.p. to BDF1 mice 24 hours after they were inoculated with one million of murine P388 leukemic cells. Antitumor activity was fully retained for each of these agents in combination with dextran ferrite.
Brusentsov
N A
NA
Glazkova
T Iu
TIu
Iavorskaia
N P
NP
Iurchenko
N Ia
NIa
D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002945:Cisplatin / Q000008:administration & dosage; D003520:Cyclophosphamide / Q000008:administration & dosage; D003609:Dactinomycin / Q000008:administration & dosage; D003630:Daunorubicin / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D004338:Drug Combinations; D005472:Fluorouracil / Q000008:administration & dosage; D007505:Iron-Dextran Complex / Q000008:administration & dosage*; D007941:Leukemia P388 / Q000188:drug therapy*; D008558:Melphalan / Q000008:administration & dosage; D008727:Methotrexate / Q000008:administration & dosage; D051379:Mice; D005641:Tegafur / Q000008:administration & dosage
D000970:Antineoplastic Agents; D004338:Drug Combinations; D005641:Tegafur; D003609:Dactinomycin; D004317:Doxorubicin; D003520:Cyclophosphamide; D007505:Iron-Dextran Complex; D002945:Cisplatin; D008558:Melphalan; D005472:Fluorouracil; D008727:Methotrexate; D003630:Daunorubicin
Protivoopukholevaia aktivnost' kompozitsiĭ tsitostatikov s dekstran-ferritom pri vvedenii mysham s leĭkozom P-388.