Polycystic ovary syndrome.
Polycystic ovary syndrome is a disorder of unknown cause characterized by anovulation, hyperandrogenism, and gonadotropin secretory abnormalities producing oligo-ovulation or anovulation. Hyperinsulinemia and insulin resistance are important features of this syndrome. Because other causes of androgen excess may produce similar clinical and biochemical findings, PCO remains a diagnosis of exclusion. Treatment is directed toward relieving symptoms of hyperandrogenemia in order to stimulate ovulation, correcting obesity, and inducing regular menses to reduce the risk of endometrial cancer.
Shelley
D R
DR
Department of Medicine, Mount Sinai Medical Center, New York, NY 10029.
Dunaif
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D005260:Female; D006628:Hirsutism / Q000188:drug therapy; D006801:Humans; D009765:Obesity / Q000628:therapy; D010062:Ovulation Induction; D011085:Polycystic Ovary Syndrome / Q000175:diagnosis / Q000628:therapy