title: Increase in hematocrit by nifedipine in hypertensive patients.
abstract: The hematocrit, hemoglobin, serum total protein and serum albumin concentration increased significantly following sublingual administration of nifedipine in patients with essential hypertension (p less than 0.05). The mean increase in hematocrit at 60 min after administration was 1.5%. The results suggest a decrease in plasma volume, perhaps due to diuresis and a shift of fluid from the intravascular to the extravascular space.
authors: Cardiovascular Hospital of Central Japan.
authors: Y
authors: Y
authors: Takayama
authors: S
authors: S
authors: Ichikawa
authors: T
authors: T
authors: Sakamaki
authors: K
authors: K
authors: Murata
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D001798:Blood Proteins / Q000378:metabolism; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006400:Hematocrit; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000188:drug therapy / Q000503:physiopathology; D008297:Male; D009543:Nifedipine / Q000009:adverse effects* / Q000627:therapeutic use; D011188:Potassium / Q000097:blood; D012709:Serum Albumin / Q000378:metabolism; D012964:Sodium / Q000097:blood
chemical_list: D001798:Blood Proteins; D012709:Serum Albumin; D012964:Sodium; D009543:Nifedipine; D011188:Potassium