The response of broilers' adiposity to testosterone after embryonic exposure to androgen and tamoxifen.
1. The effects of early exposure of heavy breed (HB) chicks to an anti-oestrogen (tamoxifen--TAM) and to an androgen which cannot be aromatised (5 alpha-dihydrotestosterone--DHT) on subsequent adiposity and its response to testosterone were studied. 2. Embryonic TAM administration reduced adiposity in females but not in males at 8 weeks of age. Embryonic DHT produced similar responses but to a lesser extent. 3. Testosterone propionate (TP) administration during growth had no effect on adiposity in any of the treated groups but TP reduced adiposity in males which had been exposed to DHT at the embryonic stage.
Rozenboim
I
I
Department of Animal Science, Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel.
Robinzon
B
B
Ron
B
B
Arnon
E
E
Snapir
N
N
D000273:Adipose Tissue / Q000187:drug effects / Q000254:growth & development*; D000818:Animals; D002642:Chick Embryo / Q000187:drug effects; D002645:Chickens / Q000254:growth & development*; D013196:Dihydrotestosterone / Q000494:pharmacology*; D005260:Female; D008297:Male; D009929:Organ Size / Q000187:drug effects; D013629:Tamoxifen / Q000494:pharmacology*; D013739:Testosterone / Q000494:pharmacology*
D013196:Dihydrotestosterone; D013629:Tamoxifen; D013739:Testosterone