Hst-3: an X-linked hybrid sterility gene.
A gene, Hst-3, responsible for sterility in F1 males from crosses between Mus spretus and laboratory strains of mice such as C57BL/6, has been localized on the distal part of the X chromosome, using both DNA probes and biochemical markers on a panel of F1(C57BL/6 x SEG) x C57BL/6 backcross males. This gene may be a model for studying mammalian hybrid sterility.
Guénet
J L
JL
Unité de Génétique des Mammifères de l'Institut Pasteur, Paris, France.
Nagamine
C
C
Simon-Chazottes
D
D
Montagutelli
X
X
Bonhomme
F
F
D000818:Animals; D015139:Blotting, Southern; D003433:Crosses, Genetic; D005260:Female; D005796:Genes; D008040:Genetic Linkage; D007248:Infertility, Male / Q000235:genetics*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009115:Muridae; D014960:X Chromosome