[Relation between disorders of systemic microcirculation and chemotactic activity of macrophages in children with appendicular peritonitis].
As many as 58 children aged 3 to 14 years operated on for destructive forms of appendicitis complicated by diffuse peritonitis were examined for microcirculation of eye conjunctiva microvessels using biomicroscopy and for chemotactic++ activity of macrophages in an area of aseptic inflammatory reaction. The correlation analysis made it possible to reveal specific dependence of macrophagal chemotaxis on primary derangement in one or another component of the microcirculatory bed, the extent of diminution of the arteriolar, capillary and venular lumen as well as on the impairment of blood aggregation in microvessels. Detoxication therapy contributed to the improvement of microcirculation and the growth of the release of macrophages to the area of aseptic inflammatory reaction.
Stepanova
N A
NA
Tsvetkova
E I
EI
D000293:Adolescent; D001064:Appendicitis / Q000150:complications / Q000276:immunology / Q000503:physiopathology*; D002633:Chemotaxis / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D003228:Conjunctiva / Q000098:blood supply*; D006801:Humans; D007511:Ischemia / Q000209:etiology / Q000276:immunology*; D008264:Macrophages / Q000276:immunology*; D008833:Microcirculation / Q000503:physiopathology; D010538:Peritonitis / Q000209:etiology / Q000276:immunology / Q000503:physiopathology*
Vzaimosviaz' narusheniĭ sistemnoĭ mikrotsirkuliatsii i khemo- taksicheskoĭ aktivnosti makrofagov u deteĭ s appendikuliarnym peritonitom.