The effect of intrathecal baclofen on the lower urinary tract in paraplegia.
The effect of intrathecal baclofen on urethral pressure was investigated in 6 spinal cord injured patients. Although the response was inconsistent, and further studies are necessary to define its role more clearly in the bladder management of these patients, its possible application as an alternative to sensory rhizotomy to improve bladder emptying in patients having sacral nerve stimulation procedures is discussed.
Talalla
A
A
McMaster University, Hamilton, Ontario, Canada.
Grundy
D
D
Macdonell
R
R
D001418:Baclofen / Q000627:therapeutic use*; D006801:Humans; D007278:Injections, Spinal; D007866:Leg; D008297:Male; D009129:Muscle Tonus / Q000187:drug effects; D010264:Paraplegia / Q000188:drug therapy* / Q000503:physiopathology; D010410:Penile Erection / Q000187:drug effects; D011312:Pressure; D014521:Urethra / Q000503:physiopathology; D014551:Urinary Tract / Q000187:drug effects* / Q000503:physiopathology; D014554:Urination / Q000187:drug effects
D001418:Baclofen