title: Cytochemical localization of calcium in the corpus Luysi of the rat after ischemia.
abstract: The postischemic ultrastructural localization of calcium in the corpus Luysi of the rat was investigated. We observed an increased calcium sequestration in mitochondria of some neurons and astrocytes in the post-ischemic period. Calcium precipitates were also present in Golgi vesicles, multivesicular bodies, synaptic vesicles, synaptic clefts and some channels of the smooth endoplasmic reticulum. These cellular organelles may be involved in the control of intracellular calcium exchange. Abundant Ca2+ precipitates were found in the cytoplasmic matrix of some neurons and astrocytes. Occasional neurons exhibited changes in cytoskeleton elements. Ultrastructural alterations in the myelin sheaths were noticed. Increased amounts of calcium were found between disjuncted myelin lamellae. The possible role of calcium in ischemic neuronal damage is briefly discussed.
authors: Medical Research Centre, Polish Academy of Sciences, Warsaw.
authors: A
authors: A
authors: Zareba-Kowalska
authors: B
authors: B
authors: Gajkowska
mesh_terms: D000818:Animals; D001253:Astrocytes / Q000378:metabolism / Q000648:ultrastructure; D002545:Brain Ischemia / Q000378:metabolism* / Q000473:pathology; D002118:Calcium / Q000378:metabolism*; D003712:Dendrites / Q000378:metabolism / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D008928:Mitochondria / Q000378:metabolism / Q000648:ultrastructure; D010487:Periaqueductal Gray / Q000378:metabolism* / Q000473:pathology / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D002118:Calcium