title: [Reproductive death of the apoptosis type in irradiated cells of the BW5147 thymoma].
abstract: The method of flow cytofluorometry and biochemical analysis were used to study the pattern and kinetics of the postirradiation death of proliferating BW5147 lymphoid cells. Irradiation with a dose of 10 Gy was shown to induce thymoma cell death by apoptosis. Radiation-induced synchronous transfer of part of cells from G1 to S-stage and blocking of all cells at G2/M stages of the cell cycle preceded the cell death. Decreasing of the growth factor content in a medium through its depletion or cultivation in conditions of low serum content accelerated cell death. A possible relationship between cell death and proliferation is discussed.
authors: I I
authors: II
authors: Kruman
authors: N P
authors: NP
authors: Matylevich
authors: V N
authors: VN
authors: Afanas'ev
authors: S R
authors: SR
authors: Umanskiĭ
mesh_terms: D000818:Animals; D002453:Cell Cycle / Q000528:radiation effects; D002455:Cell Division / Q000528:radiation effects*; D002470:Cell Survival / Q000528:radiation effects*; D002588:Cesium Radioisotopes; D004273:DNA, Neoplasm / Q000528:radiation effects; D005720:Gamma Rays; D066298:In Vitro Techniques; D051379:Mice; D013945:Thymoma / Q000473:pathology*; D013953:Thymus Neoplasms / Q000473:pathology*
chemical_list: D002588:Cesium Radioisotopes; D004273:DNA, Neoplasm
vernacular_title: Reproduktivnaia gibel' obluchennykh kletok timomy BW5147 po tipu apoptoza.