title: Alterations in pulmonary mechanics after transfusion in anemic preterm infants.
abstract: Pulmonary mechanics were studied in ten anemic preterm infants using an esophageal balloon and mask, before and after transfusion with 10 ml/kg of packed RBC. Their mean birth weight was 1212 +/- 323 g and gestational age was 29.27 +/- 2.4 wk. Transfusions were carried out at a mean postnatal age of 41.9 +/- 21.8 days. The mean Hct increased from 28 +/- 3.1 to 38.3 +/- 3.3%. Dynamic lung compliance decreased in all infants after transfusion. There was a 33.8% increase in resistance; the work of breathing increased after transfusion. These changes might be due to volume overload or increased lung water content.
authors: Department of Pediatrics, Medical College of Wisconsin, Milwaukee.
authors: P
authors: P
authors: Sasidharan
authors: R
authors: R
authors: Heimler
mesh_terms: D000403:Airway Resistance; D000740:Anemia / Q000503:physiopathology* / Q000628:therapy; D001696:Biomechanical Phenomena; D001803:Blood Transfusion / Q000592:standards*; D002404:Catheterization; D004947:Esophagus; D005069:Evaluation Studies as Topic; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D007441:Intubation, Gastrointestinal; D008170:Lung Compliance; D012119:Respiration / Q000502:physiology*; D012129:Respiratory Function Tests; D014939:Work of Breathing