title: [Usefulness of ioversol (MP-328) in angiocardiography--a multicenter comparative study with iopamidol].
abstract: A randomized, controlled study was conducted to compare the radiographic efficacy, safety and usefulness of ioversol and iopamidol in 146 patients undergoing angiocardiography at six institutions. The hemodynamic and electrocardiographic effects were clinically insignificant and comparable for both agents. Ioversol demonstrated lower incidence of adverse reactions and less heat sensation in left coronary arteriography than those with iopamidol. Overall radiographic efficacy with ioversol was slightly better than with iopamidol, according to the evaluation by both investigators and committee members. Ioversol appears to be very useful for angiocardiography. This comparative study demonstrated the value of safety and efficacy evaluation criteria suggested by the preceding clinical trial with ioversol.
authors: Department of Radiology, Osaka University Medical School.
authors: S
authors: S
authors: Morimoto
authors: T
authors: T
authors: Kozuka
authors: M
authors: M
authors: Takamiya
authors: K
authors: K
authors: Kimura
authors: S
authors: S
authors: Matsuyama
authors: S
authors: S
authors: Kuribayashi
authors: A
authors: A
authors: Shigeta
authors: J
authors: J
authors: Umemura
authors: J
authors: J
authors: Harada
authors: T
authors: T
authors: Yamada
mesh_terms: D000328:Adult; D000368:Aged; D000790:Angiocardiography; D003287:Contrast Media; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007479:Iopamidol; D008297:Male; D008875:Middle Aged; D014283:Triiodobenzoic Acids
chemical_list: D003287:Contrast Media; D014283:Triiodobenzoic Acids; D007479:Iopamidol; C054871:ioversol