[HPV-induced subclinical lesions of the male genitalia. Use of a colposcope].
Thirty-nine HIV-negative men, without apparent genital warts, were evaluated for evidence of subclinical genital condylomata by visual examination of the genitalia with colposcopy after the application of 5% acetic acid. 24 patients (group I) had a history of recurrent genital condylomata; 8 (group II) were sexual partners of women with HPV-related lesions and 7 (group III) presented another sexually transmitted disease. Under colposcopic magnification, acetowhite areas were biopsied for conventional histology and in situ hybridization using 6/11, 16/18 and 31/35/51 HPV-DNA probes. Colposcopy and histologic features were positive for condylomata acuminata in 16 patients of group III (14%). HPV 16/18 - whose oncogenic potentiality is well known - was detected in 3 patients: of these, one patient of group I presented a histologic picture suggestive of bowenoid papulosis.
Massone
L
L
Divisione di Dermatologia, Centro MTS, E.O. Ospedali Galliera, Genova.
Anonide
A
A
Pestarino
A
A
Solari
G
G
Priano
L
L
Isola
V
V
D000293:Adolescent; D000328:Adult; D003127:Colposcopy; D003218:Condylomata Acuminata / Q000175:diagnosis* / Q000473:pathology; D015344:DNA Probes, HPV; D003937:Diagnosis, Differential; D005834:Genital Neoplasms, Male / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged
D015344:DNA Probes, HPV
Lesioni subcliniche HPV-indotte dei genitali maschili. Uso del colposcopio.