title: Hyperimmunoglobulinemia E syndrome of neonatal onset.
abstract: A case of hyperimmunoglobulinemia IgE with recurrent infections of neonatal onset and unfavourable evolution is described. The first clinical finding was the appearance of maculopapular rash in the skin when the child was fifteen days old. From this period onwards, respiratory and cutaneous infections were continuous, leading to a progressive deterioration of the general condition, and malnutrition, which ended fatally at the age of three years. IgE levels were measured on several occasions, this being 17 IU/ml at the onset of the symptoms; afterwards, the mean value was 17.680 IU/ml (Range: 14.9-32.710 IU/ml).
authors: Departamento de Pediatría y Anatomía Patológica, Facultad de Medicina, Universidad de Alicante, Spain.
authors: M
authors: M
authors: Juste
authors: J
authors: J
authors: González Perabá
authors: M J
authors: MJ
authors: Mayol
authors: M
authors: M
authors: Moya
mesh_terms: D004198:Disease Susceptibility; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications / Q000151:congenital*; D007073:Immunoglobulin E / Q000032:analysis*; D007231:Infant, Newborn; D007589:Job Syndrome / Q000150:complications / Q000151:congenital* / Q000276:immunology; D008297:Male; D009748:Nutrition Disorders / Q000209:etiology; D012008:Recurrence; D012141:Respiratory Tract Infections / Q000209:etiology; D012600:Scoliosis / Q000150:complications; D012874:Skin Diseases, Infectious / Q000209:etiology; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000209:etiology
chemical_list: D007073:Immunoglobulin E