Treatment of bacterial vaginosis in pregnancy with a lactate gel.
10 pregnant women with bacterial vaginosis were treated vaginally with a low-pH lactate gel intermittently during 6 weeks. Reappearance of a lactobacillus-dominated vaginal flora was observed after a few days treatment in all patients. All women experienced a subjective disappearance of abnormal vaginal discharge and malodour. This local treatment restores the normal vaginal acidity and facilitates recolonization with lactobacilli. It may be preferable to oral antimicrobial therapy, especially during pregnancy.
Holst
E
E
Department of Clinical Microbiology, University Hospital, Lund, Sweden.
Brandberg
A
A
D000282:Administration, Intravaginal; D001424:Bacterial Infections / Q000188:drug therapy*; D005260:Female; D005782:Gels; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007773:Lactates / Q000008:administration & dosage / Q000627:therapeutic use*; D007778:Lactobacillus / Q000254:growth & development; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy*; D014621:Vagina / Q000382:microbiology; D014627:Vaginitis / Q000188:drug therapy*
D005782:Gels; D007773:Lactates