Perfluorocarbon gases in the suprachoroidal space of rabbit eyes.
Four perfluorocarbon gases were injected into the suprachoroidal space of rabbit eyes. Temporary, expanding choroidal detachments were observed in all cases. Depending on the amount of gas injected (0.1 or 0.2 cc, respectively), they lasted 1 or 2 days in the case of perfluoromethane, 4 or 5 days with perfluoroethane, 6 or 8 days with perfluoropropane, and 9 or 11 days with perfluoro-N-butane. Due to its longevity, perfluoro-N-butane appeared to be the most suitable gas for temporary "buckling" of the suprachoroidal space in rabbit eyes.
Mittl
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RN
College of Physicians and Surgeons, Columbia University, Edward S. Harkness Eye Institute, Columbia-Presbyterian Medical Center, New York, NY 10032.
D000818:Animals; D002829:Choroid; D015862:Choroid Diseases / Q000000981:diagnostic imaging; D005466:Fluorocarbons / Q000008:administration & dosage*; D005654:Fundus Oculi; D005740:Gases / Q000008:administration & dosage; D011817:Rabbits; D012163:Retinal Detachment / Q000628:therapy*; D013997:Time Factors; D014463:Ultrasonography; D014822:Vitreous Body / Q000187:drug effects
D005466:Fluorocarbons; D005740:Gases