[The effect of ionizing radiation on the respiration of rat thymocytes].
The oligomycin-sensitive component of the rate of oxygen consumption by rat thymocytes increased by 22% after X-irradiation. The postirradiation increase in the thymocyte respiration rate was connected with the impairment of a balance between sodium, potassium and calcium and with the protein synthesis activation, and was independent of lymphokine production by lipoxygenase. Irradiation was ineffective with respect to electron transport in the respiratory chain and electrogenic leakages through the inner membrane of thymocyte mitochondria.
Gudz'
T I
TI
Novgorodov
S A
SA
Pandelova
I G
IG
Goncharenko
E N
EN
D000818:Animals; D003513:Cycloheximide / Q000494:pharmacology; D066298:In Vitro Techniques; D007811:Lanthanum / Q000494:pharmacology; D009637:Masoprocol / Q000494:pharmacology*; D009840:Oligomycins / Q000494:pharmacology; D010042:Ouabain / Q000494:pharmacology; D010101:Oxygen Consumption / Q000187:drug effects / Q000528:radiation effects*; D051381:Rats; D013950:Thymus Gland / Q000166:cytology* / Q000528:radiation effects
D009840:Oligomycins; D010042:Ouabain; D007811:Lanthanum; D009637:Masoprocol; D003513:Cycloheximide
Vliianie ioniziruiushchego izlucheniia na dykhanie timotsitov krys.