[Cefuroxime axetil (Zinnat)--laboratory and clinical study].
The authors investigated the antibacterial action of cefuroxim in vitro and proved its relatively broad spectrum of action. Administration of the esterified form, Zinnat, produced very satisfactory therapeutic concentrations of cefuroxim in serum, bile tissue of operated gallbladders. The prophylactic administration of the combined parenteral and oral form of cefuroxim proved excellent in biliary surgery in twenty patients.
Vyhnánek
F
F
Katedra chirurgie LFH UK, Praha.
Hejzlar
M
M
Procházka
M
M
Pellar
T
T
St'astná
L
L
Silarová
J
J
Kittnar
E
E
Vedral
T
T
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002444:Cefuroxime / Q000031:analogs & derivatives* / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use; D002763:Cholecystectomy; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011292:Premedication; D011355:Prodrugs / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use
D011355:Prodrugs; D002444:Cefuroxime; C040738:cefuroxime axetil
Axetil cefuroxim (Zinnat)--laboratorní a klinické studie.