Colony-stimulating factors.
Recombinant hematopoietic colony-stimulating factors have profound effects on developing and mature granulocytes, macrophages, and lymphocytes. Use of these agents for treatment of disease may result in a variety of adverse cutaneous reactions. The recent discovery of colony-stimulating factor production by keratinocytes and dermal cells suggests that these agents may also be significant in cutaneous homeostasis and in the pathogenesis of cutaneous diseases.
Wakefield
P E
PE
Dermatology Service, Walter Reed Army Medical Center, Washington, DC 20307-5001.
James
W D
WD
Samlaska
C P
CP
Meltzer
M S
MS
D002454:Cell Differentiation; D002455:Cell Division; D003115:Colony-Stimulating Factors / Q000009:adverse effects / Q000096:biosynthesis / Q000378:metabolism / Q000627:therapeutic use; D006801:Humans; D009503:Neutropenia / Q000188:drug therapy; D012867:Skin / Q000166:cytology
D003115:Colony-Stimulating Factors