[The treatment of juvenile migraine using flunarizine or propranolol].
The clinical efficacy of flunarizine and propranolol for the prevention of migraine attacks was assessed in 33 children in a double blind study. After a run-in phase of one month, 32 patients started the active medication. A reduction in the number of migraine attacks was observed in 75% of the flunarizine group and in 73.8% of the propranolol group. Propranolol also reduced the severity of attacks. Transient side effects were observed in 3 of 17 of the flunarizine group and in 5 of 15 of the propranolol group. The most frequent side effect was increased fatigue, which required interruption of therapy in 2 patients of the propranolol group.
Lütschg
J
J
Kinderklinik, Kantonsspital Bruderholz.
Vassella
F
F
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004311:Double-Blind Method; D005260:Female; D005444:Flunarizine / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008881:Migraine Disorders / Q000517:prevention & control*; D011433:Propranolol / Q000009:adverse effects / Q000627:therapeutic use*; D011795:Surveys and Questionnaires
D011433:Propranolol; D005444:Flunarizine
Behandlung der kindlichen Migräne mit Flunarizin bzw. Propranolol.