title: HLA-antigens in a Tunisian familial chondrocalcinosis.
abstract: Thirty members of a Tunisian family with hereditary chondrocalcinosis were typed for HLA-A, B, and DR antigens: 7 affected and 23 unaffected subjects in three consecutive generations. The haplotype A1 B12 DR3 was found in all affected subjects and in 8 unaffected members. Chondrocalcinosis in this family may be associated with the haplotype A1 B12 DR3. The mode of transmission was autosomal dominant with incomplete penetrance.
authors: Service de Rhumatologie, Hôpital Le Rabta Tunis, Tunisie.
authors: M
authors: M
authors: Hamza
authors: K
authors: K
authors: Ayed
authors: R
authors: R
authors: Bardi
authors: L
authors: L
authors: Gebuhrer
authors: H
authors: H
authors: Betuel
authors: T
authors: T
authors: Bardin
authors: R
authors: R
authors: Plaetke
authors: M
authors: M
authors: Lathrop
mesh_terms: D002805:Chondrocalcinosis / Q000208:ethnology / Q000235:genetics*; D003241:Consanguinity; D004198:Disease Susceptibility; D005260:Female; D005799:Genes, Dominant; D005819:Genetic Markers; D006680:HLA Antigens / Q000032:analysis*; D006239:Haplotypes; D006801:Humans; D008297:Male; D010375:Pedigree; D014416:Tunisia
chemical_list: D005819:Genetic Markers; D006680:HLA Antigens