Prediction of the halothane (Hal) genotypes by means of linked marker loci (Phi, Po2, Pgd) in Quebec Landrace pigs.
Quebec Landrace pigs (n = 896) were halothane tested and blood samples were taken for the determination of Phi, Po2 and Pgd phenotypes. The incidence of the halothane positive pigs was 5.3%. The frequencies of the favorable alleles PhiA, Po2S and PdgA were respectively 29.2%, 39.6% and 64.4%. The highest linkage disequilibrium was found between Hal-Phi (0.0606) followed by Hal-Pgd (0.0428) and Hal-Po2 (-0.0308). Alleles PhiB, PgdB and Po2F were associated respectively with 97%, 81% and 74% of Haln haplotypes. It was concluded that a selection in order to increase the favorable marker loci PhiA and PgdA would reduce the Haln frequency in Quebec Landrace pigs.
Doizé
F
F
Laboratoire de Biomédecine Comparée, Faculté de Médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec.
Roux
I
I
Martineau-Doizé
B
B
DeRoth
L
L
D000483:Alleles; D000818:Animals; D005787:Gene Frequency; D008040:Genetic Linkage; D005819:Genetic Markers; D006221:Halothane / Q000009:adverse effects*; D006239:Haplotypes; D015994:Incidence; D015810:Linkage Disequilibrium; D008305:Malignant Hyperthermia / Q000209:etiology / Q000235:genetics / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000235:genetics*
D005819:Genetic Markers; D006221:Halothane