[The role of arachidonic acid metabolites in the skin].
The metabolism of the arachidonic acid (AA) in normal skin is presented, and the role of its metabolites (eicosanoids) in pathogenesis of psoriasis is reviewed. Beside, possibility of the treatment of psoriasis by means of fish oil and eicosapentaenoic acid (EPA) is discussed.
Brus
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Katedry i Zakładu Farmakologii w Rokitnicy Slaskiej.
Rzempołuch
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Wylezoł
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D001095:Arachidonic Acids / Q000378:metabolism*; D015118:Eicosapentaenoic Acid / Q000378:metabolism / Q000627:therapeutic use*; D005395:Fish Oils / Q000627:therapeutic use*; D006801:Humans; D015289:Leukotrienes / Q000378:metabolism; D010741:Phospholipases A / Q000037:antagonists & inhibitors / Q000378:metabolism; D011453:Prostaglandins / Q000378:metabolism; D011565:Psoriasis / Q000209:etiology / Q000378:metabolism* / Q000628:therapy; D012867:Skin / Q000378:metabolism*
D001095:Arachidonic Acids; D005395:Fish Oils; D015289:Leukotrienes; D011453:Prostaglandins; D015118:Eicosapentaenoic Acid; D010741:Phospholipases A
Rola metabolitów kwasu arachidonowego w skórze.