title: [Structure and properties of collagen in leukemia].
abstract: Collagen I was isolated from human bone tissue and from mice bone tissue of the AKR-50 strain at the pronounced stage of leukosis. Dissimilarity of native and leukemic collagens was exhibited after evaluation of their amino acid composition, electrophoretic mobility in polyacrylamide gel containing SDS, content of the carbohydrate moiety as well as of isopoints, elution profiles in reverse-phase chromatography and gel filtration and electron microscopy of SLS-crystallites. Impairments of collagen processing in leukemia appear to be responsible for its alterations in structure and properties.
authors: T T
authors: TT
authors: Volodina
authors: V D
authors: VD
authors: Drozdova
authors: T N
authors: TN
authors: Pechenova
authors: A K
authors: AK
authors: Shimanovskaia
authors: A V
authors: AV
authors: Nartikov
authors: N A
authors: NA
authors: Nosal'
authors: V B
authors: VB
authors: Boĭko
authors: V G
authors: VG
authors: Bebeshko
authors: M F
authors: MF
authors: Gulyĭ
mesh_terms: D000293:Adolescent; D000596:Amino Acids / Q000737:chemistry; D000818:Animals; D002648:Child; D002675:Child, Preschool; D002851:Chromatography, High Pressure Liquid; D003094:Collagen / Q000737:chemistry* / Q000648:ultrastructure; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007223:Infant; D007525:Isoelectric Focusing; D051379:Mice; D008806:Mice, Inbred AKR; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000378:metabolism* / Q000473:pathology
chemical_list: D000596:Amino Acids; D003094:Collagen
vernacular_title: Osobennosti struktury i svoĭstv kollagena pri leĭkoze.