title: Structure of the toxin isolated from carp (Cyprinus carpio) bile.
abstract: Attempts were made to elucidate the structure of the toxin isolated from the bile of carp Cyprinus carpio, which is possibly responsible for carp poisoning. By fast atom bombardment (FAB) mass spectrometry, along with 1H- and 13C-NMR, a molecular formula of C27H48O8S containing a sulfate ester group was deduced. Those and other analytical data allowed us to conclude the structure of carp toxin to be 5 alpha-cholestane-3 alpha, 7 alpha, 12 alpha, 26, 27-pentol 26-sulfate, which agreed essentially with that of 5 alpha-cyprinol, an alcohol specific to carp bile, in which the sulfate ester at the C-26 position is lacking.
authors: Laboratory of Marine Biochemistry, Faculty of Agriculture, University of Tokyo, Japan.
authors: M
authors: M
authors: Asakawa
authors: T
authors: T
authors: Noguchi
authors: H
authors: H
authors: Seto
authors: K
authors: K
authors: Furihata
authors: K
authors: K
authors: Fujikura
authors: K
authors: K
authors: Hashimoto
mesh_terms: D000818:Animals; D001646:Bile / Q000737:chemistry*; D002347:Carps / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D008387:Marine Toxins / Q000737:chemistry*
chemical_list: D008387:Marine Toxins