title: The Yale-Brown Obsessive-Compulsive Scale: a reliability and validity study.
abstract: Twenty-eight nondepressed patients with DSM-III obsessive-compulsive disorder completed both the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) and the Leyton Obsessional Inventory (LOI) once a week for a total of three times change. In general, the correlations between the Y-BOCS change scores and the Global Ratings were significantly greater than between the LOI and the Global scores, the Y-BOCS was found to be more reliable than the LOI. Correlations were also obtained for the baseline period between the Y-BOCS and Leyton scores. At the end of a 14-week trial of clomipramine, the Y-BOCS and the LOI were again administered along with a Physician and Patient Global Rating of change. In general, the correlations between the Y-BOCS change scores and the Global Ratings were significantly greater than between the LOI and the Global Ratings. This last finding suggests that the Y-BOCS is a better measure of clinical change than is the LOI.
authors: Dept. of Psychiatry, Hennepin County Medical Center, Minneapolis, MN 55415.
authors: S W
authors: SW
authors: Kim
authors: M W
authors: MW
authors: Dysken
authors: M
authors: M
authors: Kuskowski
mesh_terms: D000328:Adult; D002997:Clomipramine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D010555:Personality Inventory; D011594:Psychometrics; D015203:Reproducibility of Results
chemical_list: D002997:Clomipramine