Determination of enzyme activities in serum for the detection of xenobiotic effects on the liver.
The determinations of enzyme activities in the serum are of considerable importance in detecting xenobiotic effects on the liver. After a brief introduction to the basics of enzyme diagnostics, the enzymes ALAT, ASAT, ICDH, LDH, SDH, GLDH, AP, gamma-GT, CHE are characterized with regard to their occurrence, their half-life periods in the serum and their clinical value. They are followed by enzyme levels and the presentation of the dynamics of enzyme activities in the serum after xenobiotic influences on the liver in humans.
Keil
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Department of Clinical Chemistry and Laboratory Medicine, Friedrich Schiller University, Jena, GDR.
D000818:Animals; D001648:Bile Canaliculi / Q000201:enzymology; D003600:Cytosol / Q000201:enzymology*; D004798:Enzymes / Q000097:blood*; D006801:Humans; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008930:Mitochondria, Liver / Q000201:enzymology; D012270:Ribosomes / Q000201:enzymology; D015262:Xenobiotics / Q000494:pharmacology*
D004798:Enzymes; D015262:Xenobiotics