Microbiology, chemotherapy and mortality of brain abscess in Newcastle-upon-Tyne between 1979 and 1988.
71 patients admitted to Newcastle Regional Neurosurgical Centre between 1979 and 1988 with a diagnosis of brain abscess are reviewed. The overall mortality was 9.9%, with an operative mortality of 7%. The bacteriology of these abscesses is discussed in detail, together with the importance of effective standardized antimicrobial treatment regimens. The low mortality figures appeared to be in direct relationship to early recognition of this condition, prompt surgical intervention and effective chemotherapy.
Richards
J
J
Department of Microbiology, General Hospital, Newcastle-upon-Tyne, England.
Sisson
P R
PR
Hickman
J E
JE
Ingham
H R
HR
Selkon
J B
JB
D000667:Ampicillin / Q000627:therapeutic use; D001421:Bacteria, Anaerobic / Q000302:isolation & purification*; D001707:Biopsy, Needle; D001922:Brain Abscess / Q000188:drug therapy / Q000382:microbiology / Q000401:mortality*; D003131:Combined Modality Therapy; D003907:Dexamethasone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004739:England / Q000453:epidemiology; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
D005839:Gentamicins; D008795:Metronidazole; D000667:Ampicillin; D003907:Dexamethasone