[Effect of hemodialysis fluids with different pH values and buffer types used in peritoneal dialysis on the phagocyte system in the peritoneal cavity. The experimental part].
In a four-hour exchange of dialysing fluid in 120 healthy mice it was checked whether and in what degree changes of the pH of the dialysing fluid in the range from 5.09 to 7.02 and change of the buffer in the dialysing fluid (acetate, lactate) have an effect on the phagocytic and bactericidal ability of the phagocytic cells in the peritoneal dialysate. The study of the count of phagocytic cells, their bactericidal ability (NBT test) and phagocytosis ability (latex test) showed that neither the type of the used buffer nor pH changes of the dialysing fluid in the range 5.09-6.18 had no effect on the defensive properties of the phagocytes in healthy peritoneal cavity. The observation of a statistically significant increase in the proportion of cells of low phagocytic ability in the group of mice receiving acetate buffer of pH 7.02 requires further studies.
Szczylik
C
C
Zakładu Immunologii CSK WAM.
Panasiuk
E
E
Urbanowska
E
E
Ratajczak
M Z
MZ
Wańkowicz
Z
Z
D000818:Animals; D002021:Buffers; D005260:Female; D015312:Hemodialysis Solutions / Q000032:analysis / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D007958:Leukocyte Count / Q000187:drug effects; D051379:Mice; D009504:Neutrophils / Q000276:immunology*; D010529:Peritoneal Cavity / Q000166:cytology*; D010531:Peritoneal Dialysis, Continuous Ambulatory; D010587:Phagocytosis / Q000187:drug effects* / Q000276:immunology
D002021:Buffers; D015312:Hemodialysis Solutions
Wpływ płynów dializacyjnych o róznych wartościach pH i rodzajach buforów stosowanych w dializie otrzewnowej na układ fagocytów jamy otrzewnowej. Cześć doświadczalna.