Antibodies to antinuclear subsets in systemic lupus erythematosus and rheumatoid arthritis.
In this study, technical, clinical and genetic aspects of anti-Ro/SSA, anti-Sm, and anti-RNP are discussed; different techniques may reveal differences in autoantibody frequencies and associations. Finally, the importance of anti-RA33, a new autoantibody characteristic of rheumatoid arthritis, is evidenced.
Smolen
J S
JS
2nd Department of Medicine, Lainz Hospital, Vienna, Austria.
Hassfeld
W
W
Graninger
W
W
Steiner
G
G
D000906:Antibodies / Q000032:analysis; D000974:Antibodies, Antinuclear / Q000032:analysis* / Q000235:genetics; D001172:Arthritis, Rheumatoid / Q000276:immunology*; D001324:Autoantigens / Q000276:immunology; D006801:Humans; D007158:Immunologic Techniques; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000235:genetics / Q000276:immunology*; D012261:Ribonucleoproteins / Q000276:immunology; D017411:Ribonucleoproteins, Small Nuclear; D055517:snRNP Core Proteins
D000906:Antibodies; D000974:Antibodies, Antinuclear; D001324:Autoantigens; D012261:Ribonucleoproteins; D017411:Ribonucleoproteins, Small Nuclear; C035356:SS-A antibodies; D055517:snRNP Core Proteins