title: Immature mediastinal teratoma in early infancy: report of one case.
abstract: Immature mediastinal teratomas are rare, found in only 1% of all mediastinal teratomas; those occurring in the neonatal period are even more rare. A male baby suffering from tachypnea, weak crying and hoarseness since birth was noted, from a chest radiograph, to have a superior mediastinal mass. This mass enlarged progressively to an extent that the airway was threatened by one month of age. After resuscitation, intubation and mechanical ventilation, the infant became respirator-dependent. Chest computed tomography and ultrasonography revealed a heterogeneous cystic tissue mass containing focal calcifications. A well-encapsulated tumor, measuring 6 x 4 x 4 cm in size, located anterior to the thymus, was successfully removed at 58 days of age. The pathology showed an immature teratoma. After operation, respiratory distress dramatically improved. However, a superior mediastinal mass reappeared on a chest roentgenogram four months later. After a short course of chemotherapy, the infant received another operation to excise a mass composed of hypertrophic thymic tissue and a small nodular mature teratoma. The patient has remained well for more than nine months now.
authors: Department of Pediatrics, National Taiwan University Hospital, Taipei, R.O.C.
authors: C H
authors: CH
authors: Chien
authors: W M
authors: WM
authors: Chuu
authors: K I
authors: KI
authors: Tsou Yau
authors: K H
authors: KH
authors: Lin
authors: M Z
authors: MZ
authors: Wu
authors: B F
authors: BF
authors: Chen
mesh_terms: D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications / Q000473:pathology*; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology; D013724:Teratoma / Q000150:complications / Q000473:pathology*