title: [Dental sac and its role in periodontal development].
abstract: The present study examined the role of the innermost layer of dental sac tissue in periodontal development. Empty bony crypts were filled with Hydroxylapatite ceramic granules of porous consistency in 5-day-old rats. After 4.5 and 24 weeks the specimens were processed for light and transmission electron microscopy. Only 4 weeks later cement regeneration was seen on ceramic surfaces with bundles of oriented collagen fibers inserting in the cementoid matrix. Ultrastructurally the newly formed cementum-like tissue was in intimate contact to the synthetic hydroxylapatite crystals. A consistent finding was the presence of an interface between cementum and the ceramic surface. The present findings question the unique role of the "investing layer" in periodontal development and the existence of cement-inducting properties of dentin.
authors: Poliklinik für Kieferorthopadie der Freien Universität Berlin.
authors: E A
authors: EA
authors: Holtgrave
mesh_terms: D000818:Animals; D025021:Cementogenesis; D003795:Dental Sac / Q000502:physiology*; D006882:Hydroxyapatites; D010519:Periodontium / Q000254:growth & development*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D006882:Hydroxyapatites
vernacular_title: Das Zahnsäckchen und dessen Bedeutung bei der Entstehung des Parodontiums.