[Experimental study on the etiology of pathogenesis of acetabular dysplasia in congenital dislocation of the hip].
In order to investigate the etiology of pathogenesis of congenital hip dislocation and acetabular dysplasia, experiments using fetuses of pregnant rabbits were conducted. The following findings were obtained. (1) Dislocation occurred in approximately 40% of total animals used. The earliest dislocation was seen 2 days after birth. (2) The hip dislocation could be relatively and easily generated by exogenous factors during the perinatal period, even without such primary cause, as hip joint dysplasia. The acetabular dysplasia could be generated secondarily to dislocation. (3) There was a difference in the cause of acetabular dysplasia between areas of the acetabulum with and without load. (4) The acetabular depth growth in the dislocated hip was more seriously impaired than the longitudinal and transverse diameters of the acetabular entrance. These results have indicated that endochondral ossification of the epiphyseal cartilage of the acetabulum in the dislocated hip was more markedly impaired than that of Y epiphyseal cartilage.
Ooishi
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Department of Orthopaedic Surgery, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
D000077:Acetabulum / Q000002:abnormalities* / Q000473:pathology; D000818:Animals; D005260:Female; D006132:Growth Plate / Q000473:pathology / Q000503:physiopathology; D006618:Hip Dislocation, Congenital / Q000209:etiology* / Q000473:pathology; D010012:Osteogenesis; D011247:Pregnancy; D011817:Rabbits