Ocular atopy and mycotic keratitis.
In a retrospective analysis, we studied the association between ocular atopy and keratomycosis. Forty-one (26.3%) of 156 patients with fungal corneal ulcers were found to have preexisting allergic conjunctivitis. All patients had been using a combination of antibiotics and corticosteroids before developing the corneal ulcer. Fungus isolation on Sabouraud's agar medium was obtained in 74.8% (31/42) ulcers. The most common fungi isolated were Fusarium (32.3%) and Aspergillus (29%). One percent silver sulfadiazine was used as an antifungal agent in these patients. Overall efficacy of this drug was found to be 77.8%, with Fusarium being the most sensitive (87.5%).
Vajpayee
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RB
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.
Gupta
S K
SK
Bareja
U
U
Kishore
K
K
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D003233:Conjunctivitis, Allergic / Q000150:complications*; D015821:Eye Infections, Fungal / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D005260:Female; D005658:Fungi / Q000187:drug effects / Q000302:isolation & purification; D006801:Humans; D007634:Keratitis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D012189:Retrospective Studies; D012837:Silver Sulfadiazine / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D012837:Silver Sulfadiazine