Retinal origin of VECP delays as revealed by simultaneously recorded ERG to patterned stimuli.
Electroretinal and electrocortical potentials evoked by reversing checkerboards (PERG, PVECP) were simultaneously recorded in diseases of the central retina (10 patients) and in tumor-related optic nerve disorders (11 patients) exhibiting comparable P-100 delays in the PVECP. Retinal diseases showed a peak-time delay both in the PERG and in the PVECP, while optic nerve disorders revealed no delay in the PERG. Thus, simultaneous recording of PERG and PVECP may differentiate retinal from postretinal disorders of the visual system. The method also may provide information about the site of an underlying disorder in cases of visual disturbance without obvious changes of the ocular fundus.
Lorenz
R
R
Max-Planck-Institute for Physiological and Clinical Research, Bad Nauheim, Germany.
Heider
W
W
D003390:Cranial Nerve Neoplasms / Q000503:physiopathology; D004596:Electroretinography; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000503:physiopathology; D008297:Male; D009901:Optic Nerve Diseases / Q000503:physiopathology; D010364:Pattern Recognition, Visual; D012160:Retina / Q000503:physiopathology*; D012164:Retinal Diseases / Q000503:physiopathology; D014792:Visual Acuity