title: [Lipomatous atrophy of the parotid gland in chronic alcohol consumption].
abstract: The effect of chronic ethanol consumption on the morphology of the rat parotid gland was investigated. After feeding an ethanol diet containing 36% of total calories as ethanol for 90 days light microscopic and electron microscopic investigations of the parotid gland tissue showed a striking fat accumulation compared to control rats. Besides interstitial fat tissue dispositions, fat droplets of various size occurred in most of the acinar cells. Additional morphometric investigations revealed a decrease in mean acinar cell volume (-21.9% p greater than 0.001). The latter finding reflects an atrophy of the secretory parenchyma and appears to be responsible for the impaired saliva secretion after chronic ethanol consumption which has been observed in former studies.
authors: Universitäts-HNO-Klinik Heidelberg.
authors: H
authors: H
authors: Maier
authors: H K
authors: HK
authors: Seitz
authors: B
authors: B
authors: Mayer
authors: D
authors: D
authors: Adler
authors: G
authors: G
authors: Mall
authors: I A
authors: IA
authors: Born
mesh_terms: D000428:Alcohol Drinking / Q000009:adverse effects*; D000818:Animals; D001284:Atrophy / Q000473:pathology; D000431:Ethanol / Q000633:toxicity*; D008055:Lipids / Q000032:analysis; D008297:Male; D008854:Microscopy, Electron; D010306:Parotid Gland / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains; D012463:Saliva / Q000378:metabolism
chemical_list: D008055:Lipids; D000431:Ethanol
vernacular_title: Lipomatöse atrophie der Glandula parotis bei chronischem Alkoholkonsum.