Yersinia enterocolitica in the synovial membrane of patients with Yersinia-induced arthritis.
Using a monospecific rabbit antibody against Yersinia enterocolitica outer membrane protein 1, we examined synovial biopsy specimens from 7 patients with Yersinia-induced arthritis. Yersinia were demonstrated in the synovial membrane by indirect immunofluorescence in 4 patients with Yersinia-induced arthritis, but not in 6 control patients with Salmonella-induced arthritis or with rheumatoid arthritis. These findings suggest the persistence of Yersinia in the joints of patients with Yersinia-induced arthritis.
Hammer
M
M
Division of Rheumatology, Medizinische Hochschule Hannover, Federal Republic of Germany.
Zeidler
H
H
Klimsa
S
S
Heesemann
J
J
D000328:Adult; D000942:Antigens, Bacterial / Q000276:immunology; D001170:Arthritis, Infectious / Q000276:immunology / Q000382:microbiology* / Q000473:pathology; D001706:Biopsy; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008297:Male; D008875:Middle Aged; D013583:Synovial Membrane / Q000276:immunology / Q000382:microbiology* / Q000473:pathology; D015009:Yersinia Infections / Q000276:immunology / Q000473:pathology; D015008:Yersinia enterocolitica / Q000276:immunology / Q000302:isolation & purification* / Q000648:ultrastructure
D000942:Antigens, Bacterial