Antigenic property of pediocin AcH produced by Pediococcus acidilactici H.
Pediocin AcH, a bacteriocin of Pediococcus acidilactici H, inhibits the growth of several food spoilage and pathogenic bacteria. The antigenic property of partially purified pediocin AcH was tested by immunizing mice and a rabbit. Pediocin AcH was not immunogenic in these animals as determined by immunoblotting even after conjugation to bovine serum albumin. The non-immunogenic nature of pediocin AcH, its non-toxicity to laboratory animals and its hydrolysis by gastric proteolytic enzymes may be considered favourably in its possible use as a food preservative.
Bhunia
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Department of Animal Science, University of Wyoming, Laramie 82071.
Johnson
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Ray
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Belden
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D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis*; D000942:Antigens, Bacterial / Q000276:immunology*; D001430:Bacteriocins / Q000276:immunology* / Q000302:isolation & purification; D004797:Enzyme-Linked Immunosorbent Assay; D005516:Food Microbiology; D005519:Food Preservation; D015151:Immunoblotting; D051379:Mice; D008807:Mice, Inbred BALB C; D000070017:Pediocins; D010376:Pediococcus / Q000276:immunology*; D011817:Rabbits
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D001430:Bacteriocins; D000070017:Pediocins; C074288:pediocin PA-1