[Cholinergic pyramidal neurons of the motor region of human neocortex].
By means of histochemical methods for revealing +choline acetyltransferase (ChAT) and acetylcholinesterase (AChE) cytoarchitectonic of the field 4 of the motor cortex of the cerebrum has been studied in 5 persons at the age of 33-65 years. An essential part of neurons at revealing AChE and most of them at revealing ChAT do not react. Among giant pyramidal neurons (Bets) according to ChAT activity, 4 types are distinguished: neurons with low, middle, high and very high activity. The presence of ChAT is ascertained in middle and large pyramidal neurons of the III layer. Presence of ChAT-positive synapses is demonstrated in apical dendrites. A conclusion is made that less part of the pyramidal in the III, V layers are cholinergic ones.
Motavkin
P A
PA
Okhotin
V E
VE
Sulimov
G Iu
GIu
D000109:Acetylcholine / Q000096:biosynthesis; D000110:Acetylcholinesterase / Q000378:metabolism*; D000328:Adult; D000368:Aged; D002795:Choline O-Acetyltransferase / Q000378:metabolism*; D003712:Dendrites / Q000201:enzymology; D006801:Humans; D008875:Middle Aged; D009044:Motor Cortex / Q000473:pathology* / Q000648:ultrastructure; D009046:Motor Neurons / Q000201:enzymology*
D002795:Choline O-Acetyltransferase; D000110:Acetylcholinesterase; D000109:Acetylcholine
Kholinergicheskie piramidnye neĭrony dvigatel'noĭ oblasti neokorteksa cheloveka.