A clinical application of iodine quantitation using digital fluorography.
A preliminary clinical study of 20 patients is described in which a method of iodine quantitation in vitro using digital fluoroscopy was applied to the intravenous urogram. It was possible to quantitate iodine levels, in terms of mass thickness, in both the renal parenchyma and collecting system in 38 of 40 kidneys studied (20 patients). In the two kidneys on which measurements could not be made, the cause of failure was subtraction artefact due to movement of bowel gas, compounded in one case by poor renal opacification. The variations of iodine mass thickness against time were plotted and their forms were similar to dynamic computed tomography and magnetic resonance imaging studies of transplanted kidneys. Potential clinical applications of this method, in particular the functional assessment of the dilated upper urinary tract, are suggested based on its ability to offer quantitative information in addition to anatomical images.
Thompson
W D
WD
Department of Radiology, North Tees General Hospital, Stockton on Tees.
Kotre
C J
CJ
Owen
J P
JP
Laker
M F
MF
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007455:Iodine / Q000493:pharmacokinetics*; D007479:Iopamidol; D007668:Kidney / Q000000981:diagnostic imaging* / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010779:Photofluorography; D010865:Pilot Projects; D013382:Subtraction Technique
D007455:Iodine; D007479:Iopamidol