Sympathetic stimulation causes increased output of lymphocytes from the popliteal node in anaesthetized sheep.
Stimulation of the lumbar sympathetic chain at a frequency of 4 Hz caused a threefold increase in the lymphocyte output in efferent lymph from the popliteal node in anaesthetized sheep. The increase was accounted for by a rise in both lymph flow and lymphocyte count. Intra-arterial infusion of phentolamine (10 micrograms kg-1 min-1) abolished the nerve-mediated increases in flow and cell count.
McHale
N G
NG
School of Biomedical Science, Queen's University, Belfast.
Thornbury
K D
KD
D000818:Animals; D002465:Cell Movement; D004558:Electric Stimulation; D005260:Female; D007717:Knee; D007958:Leukocyte Count; D008196:Lymph / Q000378:metabolism; D008198:Lymph Nodes / Q000166:cytology / Q000294:innervation*; D008214:Lymphocytes / Q000378:metabolism*; D012756:Sheep; D013564:Sympathetic Nervous System / Q000502:physiology*