[The efficiency of treating ulcerative corneal lesions with fibro nectin].
The paper analyses results after experimental studies of effectiveness of medical forms of fibronectin used in a form of eye drops for treatment of infectious keratitis on a model of bacterial corneal ulcer in 30 rabbits (60 eyes). The results obtained speak about a pronounced stimulating action of fibronectin on reparative processes: almost a twice quicker epithelialization of corneal defects (by 46.8%) and a quicker reverse development of inflammatory signs as compared with the control group of animals. Results of experimental studies allow to recommend fibronectin for treatment of patients with infectious keratitis, bacterial ulcers of the cornea.
Adamova
N A
NA
Gorgiladze
T U
TU
Artemov
A V
AV
D000818:Animals; D065306:Corneal Injuries; D003320:Corneal Ulcer / Q000188:drug therapy* / Q000209:etiology; D004353:Drug Evaluation, Preclinical; D004359:Drug Therapy, Combination; D005353:Fibronectins / Q000627:therapeutic use*; D009883:Ophthalmic Solutions; D011817:Rabbits; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000209:etiology; D014945:Wound Healing / Q000187:drug effects
D005353:Fibronectins; D009883:Ophthalmic Solutions
Effektivnost' lecheniia iazvennykh porazheniĭ rogovitsy fibronektinom.