title: Irradiated homologous tarsal plate banking: a new alternative in eyelid reconstruction. Part I. Technique and animal research.
abstract: Reconstruction of full thickness eyelid defects requires the correction of both posterior lamella (tarsus, conjunctiva) and anterior lamella (skin, muscle). Tarsal substitutes including banked sclera, nasal cartilage, ear cartilage, and periosteum can be beneficial for posterior lamellar repair, while anterior lamellar replacement, including skin grafts, pedicle flaps, advancement flaps, etc., is important to cover the posterior reconstructed portion. At times, due to extensive tissue loss, the eyelid reconstruction can be particularly challenging. We have found an alternative posterior lamellar reconstructive technique utilizing irradiated homologous tarsal plate that can be particularly useful in selected cases of severe tissue loss. The experimental surgical procedure in monkeys and the histological fate of the implanted tarsus is described in Part I, and followed in Part II by our experience with this tissue in six human patients.
authors: Oculoplastic, Lacrimal, and Orbital Service, University of Ottawa, Ontario, Canada.
authors: D R
authors: DR
authors: Jordan
authors: D T
authors: DT
authors: Tse
authors: R L
authors: RL
authors: Anderson
authors: S O
authors: SO
authors: Hansen
mesh_terms: D000818:Animals; D003238:Connective Tissue / Q000473:pathology / Q000528:radiation effects / Q000637:transplantation*; D005143:Eyelids / Q000473:pathology / Q000601:surgery*; D005720:Gamma Rays; D006801:Humans; D008252:Macaca fascicularis; D014015:Tissue Banks; D014021:Tissue Preservation / Q000379:methods*