Tetracyclines in urology: current concepts.
Tetracyclines have an unusually broad spectrum of antimicrobial activity. They are generally well tolerated, with relatively few side effects compared with alternative antibiotic choices. Tetracyclines also compare favorably with newer antimicrobials, i.e., oral quinolones, with respect to cost and microbial resistance. Doxycycline's and minocycline's spectrum of antibacterial activity, pharmacokinetic profile, and safety profile make them preferred drugs when tetracyclines are indicated in urologic infections.
Cunha
B A
BA
Infectious Diseases Division, Winthrop-University Hospital, Mineola, New York.
Garabedian-Ruffalo
S M
SM
D001419:Bacteria / Q000187:drug effects; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy; D006801:Humans; D007408:Intestinal Absorption; D008219:Lymphogranuloma Venereum / Q000188:drug therapy; D008297:Male; D011467:Prostate / Q000378:metabolism; D011472:Prostatitis / Q000188:drug therapy; D011704:Pyelonephritis / Q000188:drug therapy; D013752:Tetracycline / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D013753:Tetracycline Resistance; D014018:Tissue Distribution; D014526:Urethritis / Q000188:drug therapy; D014552:Urinary Tract Infections / Q000188:drug therapy*
D013752:Tetracycline