Localisation of neurone-specific enolase (ENO2) to 12p13.
We have localised the human cDNA for neurone-specific enolase (ENO2) to chromosome region 12p13 by in situ hybridisation. Two additional smaller peaks of hybridisation to specific chromosomal subregions were observed. That on chromosome 1p36 probably represents cross-hybridisation to the locus for nonneuronal enolase (ENO1), which has been previously localised to this chromosome and with which ENO2 shares homology. A further gene for a member of the enolase family may be responsible for the hybridisation to chromosome 17.
Craig
S P
SP
Biochemistry Department, University of Oxford, UK.
Day
I N
IN
Thompson
R J
RJ
Craig
I W
IW
D002871:Chromosome Banding; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D002881:Chromosomes, Human, Pair 12; D002886:Chromosomes, Human, Pair 17; D006801:Humans; D005810:Multigene Family; D009693:Nucleic Acid Hybridization; D010751:Phosphopyruvate Hydratase / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid
D010751:Phosphopyruvate Hydratase