Digoxin-like immunoreactive substance and preterm labor.
An endogenous digoxin-like substance (DLIS) that may be related to preterm labor has been studied. Using a commercially available radioimmunoassay kit. DLIS levels were determined in 110 women, of whom 33 were in preterm labor, 27 were in labor at term, 26 had normally ongoing pregnancies before term and were not in labor, and finally 24 were at term but not in labor. Mean DLIS levels of women in preterm labor was found to be significantly high (greater than 0.2 ng/ml, p less than 0.05). Whether this finding points to a causative role for DLIS in preterm labor remains to be further investigated.
Ayhan
A
A
Department of Obstetrics and Gynecology, Faculty of Medicine, University of Hacettepe, Ankara, Turkey.
Yarali
H
H
Diker
I
I
Urman
B
B
Develioğlu
O
O
D000328:Adult; D015415:Biomarkers / Q000097:blood; D001798:Blood Proteins / Q000378:metabolism*; D002298:Cardenolides; D004077:Digoxin; D005260:Female; D005865:Gestational Age; D006801:Humans; D008423:Maternal Age; D007752:Obstetric Labor, Premature / Q000097:blood* / Q000209:etiology; D010298:Parity; D011247:Pregnancy; D011446:Prospective Studies; D011863:Radioimmunoassay; D012503:Saponins
D015415:Biomarkers; D001798:Blood Proteins; D002298:Cardenolides; D012503:Saponins; C034504:digoxin-like factors; D004077:Digoxin