title: Colony-stimulating factors.
abstract: Recombinant hematopoietic colony-stimulating factors have profound effects on developing and mature granulocytes, macrophages, and lymphocytes. Use of these agents for treatment of disease may result in a variety of adverse cutaneous reactions. The recent discovery of colony-stimulating factor production by keratinocytes and dermal cells suggests that these agents may also be significant in cutaneous homeostasis and in the pathogenesis of cutaneous diseases.
authors: Dermatology Service, Walter Reed Army Medical Center, Washington, DC 20307-5001.
authors: P E
authors: PE
authors: Wakefield
authors: W D
authors: WD
authors: James
authors: C P
authors: CP
authors: Samlaska
authors: M S
authors: MS
authors: Meltzer
mesh_terms: D002454:Cell Differentiation; D002455:Cell Division; D003115:Colony-Stimulating Factors / Q000009:adverse effects / Q000096:biosynthesis / Q000378:metabolism / Q000627:therapeutic use; D006801:Humans; D009503:Neutropenia / Q000188:drug therapy; D012867:Skin / Q000166:cytology
chemical_list: D003115:Colony-Stimulating Factors