[Results of combined treatment of malignant brain tumors with various cytostatic protocols].
Nowadays best results in the treatment of malignant brain tumors can be obtained with an interdisciplinary combined treatment (operation, radiation, antineoplastic chemotherapy). We treated 83 patients with gliomas after operation with a combined radiation/chemotherapy. Chemotherapy was performed by two different schemas (Israel n = 49, COMP n = 34). Both groups had the same structure concerning the 10 most important prognostic factors. The median survival time was found to be 26.1 months in the Israel-group and 22.8 months respectively in the COMP-group. The number of the long-time survivors is increasing in the COMP-group.
Bauer
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Abteilung Neurologie, Universität Rostock.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality; D011241:Prednisone / Q000008:administration & dosage; D011867:Radioisotope Teletherapy; D015996:Survival Rate; D014750:Vincristine / Q000008:administration & dosage
D003037:Cobalt Radioisotopes; D014750:Vincristine; D003520:Cyclophosphamide; D011241:Prednisone; D008727:Methotrexate
Ergebnisse der Kombinations-behandlung maligner Hirntumoren mit unterschiedlichen Zytostatikaprotokollen.