Characterisation of compounds isolated from the sera of horses with acute grass sickness.
Isolates were prepared from the sera of 12 horses with acute grass sickness, using methods reported to yield serum fractions associated with neurotoxicity, and their components identified by liquid chromatography and spectroscopy. All isolates were found to contain cortisol and six isolates also contained a degradation product of an analgesic drug, dipyrone. However, no recognised neurotoxin was detected.
Pemberton
A D
AD
Moredun Research Institute, Edinburgh.
Hodgson
J C
JC
Gilmour
J S
JS
Doxey
D L
DL
D000208:Acute Disease; D000818:Animals; D001342:Autonomic Nervous System Diseases / Q000097:blood / Q000662:veterinary*; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D004177:Dipyrone / Q000031:analogs & derivatives; D006734:Horse Diseases / Q000097:blood*; D006736:Horses; D006854:Hydrocortisone / Q000097:blood; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D009498:Neurotoxins / Q000097:blood* / Q000737:chemistry; D006109:Poaceae; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D009498:Neurotoxins; D004177:Dipyrone; D006854:Hydrocortisone