Cardiac risk in vascular surgery. The oral dipyridamole-thallium stress test.
The value of the oral dipyridamole-thallium stress test in identifying patients at high risk of myocardial infarction after vascular procedures has not been documented. We studied prospectively 46 patients who underwent an oral dipyridamole-thallium stress test before undergoing vascular operations. Twenty patients (43%) had a positive test result, defined by a thallium defect with reperfusion, while 26 patients had a negative test result. Myocardial infarctions were documented postoperatively in 5 (25%) of 20 of the group with positive results and 1 (4%) of 26 of the group with negative results. Three of the six myocardial infarctions were clinical; all three were in the group with positive results. No correlation was identified between dipyridamole-thallium stress test results and clinical cardiac history. A positive dipyridamole-thallium stress test result is a more sensitive predictor of postoperative myocardial infarction than ejection fraction or history of coronary artery disease. The oral dipyridamole-thallium stress test is as useful as the intravenous test in this setting.
Makaroun
M S
MS
Department of Surgery, Veterans Affairs Medical Center, Pittsburgh, PA 15240.
Shuman-Jackson
N
N
Rippey
A
A
Schreiner
D
D
Arvan
S
S
D000284:Administration, Oral; D004176:Dipyridamole / Q000008:administration & dosage; D006801:Humans; D009203:Myocardial Infarction / Q000209:etiology*; D011183:Postoperative Complications / Q000209:etiology*; D011446:Prospective Studies; D012307:Risk Factors; D013312:Stress, Physiological / Q000175:diagnosis* / Q000503:physiopathology; D013793:Thallium / Q000008:administration & dosage; D014656:Vascular Surgical Procedures
D004176:Dipyridamole; D013793:Thallium