Tetralogy of Fallot in three sibs.
We report on three sibs (2 boys, one girl) with tetralogy of Fallot from non-consanguineous parents. The first child died during corrective surgery in 1972 from irreversible right ventricular failure. Corrective surgery was successful in the 2nd son and the daughter. The occurrence of tetralogy of Fallot in 3 sibs suggests a recessive gene.
Pankau
R
R
Department of Pediatrics, University Hospital of Kiel, West Germany.
Siekmeyer
W
W
Stoffregen
R
R
D002648:Child; D002675:Child, Preschool; D005190:Family; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D008297:Male; D013771:Tetralogy of Fallot / Q000235:genetics* / Q000601:surgery