[The clinical pharmacology of antiepileptic agents].
The correct choice of an antiepileptic drug, its individual dosage and schedule of administration at the beginning of treatment and then during the maintenance therapy promotes a complete control of seizures using one anticonvulsant in 60-90% of patients. The treatment should be initiated with administration of one drug which is adequate for the given type of seizures taking into consideration that different drugs can appear effective in different patients with the same form of epilepsy. One has to choose drugs by consecutively gradually changing them. The optimization of epilepsy treatment should be performed on the basis of the knowledge of the clinicopharmacological characteristic of the main antiepileptic drugs described in the lecture.
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D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology*; D002648:Child; D004827:Epilepsy / Q000188:drug therapy / Q000378:metabolism; D006801:Humans; D007408:Intestinal Absorption / Q000187:drug effects
D000927:Anticonvulsants
Klinicheskaia farmakologiia protivoépilepticheskikh sredstv.