[Use of immozymase in the treatment of suppurative wounds].
The authors discuss the results of application of proteinase preparations immobilized on a water soluble carrier (Immozymase) and a water insoluble carrier (Profezyme) in the management of ++pyo-necrotic processes of various etiology and localization in 1,059 patients. The wounds were cleansed 1.5-2 times quicker than with the traditional methods of treatment. Immobilized proteinases possessing a prolonged therapeutic effect were found to stimulate the regeneration process. The authors believe the use of Immozymase to be promising in the treatment of purulent foci which are drained with difficulty and in intracavitary administration for treating purulent processes in the thoracic or abdominal cavity.
Gonchar
A M
AM
Kogan
A S
AS
Troitskiĭ
A V
AV
Beliaev
M D
MD
Sokolov
B N
BN
Usov
S A
SA
Danilov
D G
DG
D001419:Bacteria / Q000201:enzymology*; D001424:Bacterial Infections / Q000188:drug therapy*; D004337:Drug Carriers; D010450:Endopeptidases / Q000008:administration & dosage*; D004722:Endoribonucleases / Q000008:administration & dosage*; D004800:Enzymes, Immobilized / Q000008:administration & dosage*; D006801:Humans; D010447:Peptide Hydrolases / Q000008:administration & dosage*; D011092:Polyethylene Glycols / Q000008:administration & dosage*; D012874:Skin Diseases, Infectious / Q000188:drug therapy*; D012995:Solubility; D014867:Water; D014946:Wound Infection / Q000188:drug therapy*
D004337:Drug Carriers; D004800:Enzymes, Immobilized; D014867:Water; D011092:Polyethylene Glycols; D004722:Endoribonucleases; C044803:ds RNase; D010450:Endopeptidases; D010447:Peptide Hydrolases; C072623:immozymase
Primenenie immozimazy dlia lecheniia gnoĭnykh ran.