title: Diabetic ulcers--a clinical and bacteriological study.
abstract: In an 8 month period we have studied 100 consecutive patients with diabetic ulcers. The sex distribution was even. Eighty-three percent had non-insulin dependent diabetes mellitus. Sixty-nine percent of the ulcers were gangrenous as opposed to neuropathic and over half the ulcers involved the big toes. Osteomyclitis was seen in 44% of the patients. Staphylococcus aureus and Escherichia coli were the commonest infecting organisms at initial cultures and at repeat cultures 4 weeks later. Amoxicillin plus clavulinic acid (Augmentin) and Clindamycin were the best antimicrobial combinations in cases where the ulcers had some acute features (e.g. surrounding cellulitis).
authors: College of Health Sciences, University of Nairobi, Department of Medicine, Kenya.
authors: McLigeyo
authors: S
authors: S
authors: Oumah
authors: Otieno
authors: L
authors: L
authors: Saul
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D048909:Diabetes Complications; D005260:Female; D005534:Foot Diseases / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D006225:Hand; D006801:Humans; D007630:Kenya / Q000453:epidemiology; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012883:Skin Ulcer / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents