Are oxygen radicals responsible for the acute cardiotoxicity of doxorubicin?
Piccinini
F
F
Istituto di Farmacologia Applicata, Università di Milano, Italy.
Monti
E
E
Paracchini
L
L
Perletti
G
G
D000111:Acetylcysteine / Q000494:pharmacology; D000818:Animals; D004317:Doxorubicin / Q000037:antagonists & inhibitors / Q000633:toxicity*; D004562:Electrocardiography; D005260:Female; D005609:Free Radicals; D006331:Heart Diseases / Q000139:chemically induced* / Q000503:physiopathology; D066298:In Vitro Techniques; D009200:Myocardial Contraction / Q000187:drug effects; D010100:Oxygen / Q000633:toxicity*; D010117:Oxypurinol / Q000494:pharmacology; D051381:Rats
D005609:Free Radicals; D004317:Doxorubicin; D010117:Oxypurinol; D010100:Oxygen; D000111:Acetylcysteine