title: Malignant transformation occurring in mature cystic teratomas of the ovary.
abstract: Two cases in which tumours of contrasting malignant potential arose in mature cystic teratomas (dermoid cysts) of the ovary are presented: one patient had a spindle-cell sarcoma and the other a trabecular carcinoid. The first patient's clinical course was characterized by rapid recurrence of the tumour and death 3 months after surgery. The second patient is alive and well with no evidence of residual carcinoid, although the follow-up time is short. Since the surgical procedure of choice differs substantially if malignant transformation occurs in an ovarian dermoid cyst, the pathologist should be consulted intraoperatively in selected cases.
authors: Department of Pathology, Foothills Hospital, Calgary, Alta.
authors: G
authors: G
authors: Richardson
authors: D I
authors: DI
authors: Robertson
authors: M E
authors: ME
authors: O'Connor
authors: J G
authors: JG
authors: Nation
authors: G C
authors: GC
authors: Stuart
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D002276:Carcinoid Tumor / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D002471:Cell Transformation, Neoplastic / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D005629:Frozen Sections; D006801:Humans; D007430:Intraoperative Care / Q000379:methods / Q000592:standards; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D012509:Sarcoma / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D013724:Teratoma / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery