title: A recombination map of the human X-chromosome.
abstract: A family with 11 normal boys has been typed with DNA probes spanning the whole of the X-chromosome to observe directly the recombination events in 11 meioses from one female. This has (a) identified apparent recombination hot-spots on the X-chromosome; (b) shown the positions and numbers of cross-overs that have occurred in the p and q arms; (c) not shown any cross-overs in the centromeric region and (d) enabled the calculation of the genetic length of the X-chromosome.
authors: Department of Clinical Genetics, Birmingham Maternity Hospital, University of Birmingham, UK.
authors: R G
authors: RG
authors: Del Mastro
authors: P A
authors: PA
authors: Farndon
authors: M W
authors: MW
authors: Kilpatrick
mesh_terms: D002871:Chromosome Banding; D002874:Chromosome Mapping; D015342:DNA Probes; D005260:Female; D006801:Humans; D008297:Male; D011995:Recombination, Genetic; D014960:X Chromosome
chemical_list: D015342:DNA Probes