Metaproterenol intoxication in a dog.
Intoxication with metaproterenol, a mainly beta-2 selective agonist, was diagnosed in a dog with tachycardia, tachypnea, weakness, vomiting, and a history of exposure to the drug. Electrocardiography and echocardiography disclosed sinus tachycardia with episodes of ventricular tachycardia and exuberant systolic ventricular function, respectively. Administration of the beta blocking drugs propranolol and atenolol led to resolution of the clinical signs. Excessive sympathetic stimulation caused by metaproterenol is an unusual intoxication in dogs.
Rush
J E
JE
Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706.
Keene
B W
BW
D000818:Animals; D001145:Arrhythmias, Cardiac / Q000139:chemically induced / Q000662:veterinary; D001262:Atenolol / Q000627:therapeutic use; D004283:Dog Diseases / Q000139:chemically induced* / Q000188:drug therapy; D004285:Dogs; D004452:Echocardiography / Q000662:veterinary; D004562:Electrocardiography / Q000662:veterinary; D005260:Female; D009921:Metaproterenol / Q000506:poisoning*; D013610:Tachycardia / Q000139:chemically induced / Q000662:veterinary
D001262:Atenolol; D009921:Metaproterenol