Self recognition by the immune system.
In each organism, the immune system must acquire the ability to distinguish self from nonself. Experiments in T cell receptor transgenic mice indicate that this process involves the selection of lymphocytes in the thymus.
von Boehmer
H
H
Basel Institute for Immunology, Switzerland.
D000818:Animals; D007107:Immune System / Q000502:physiology*; D008213:Lymphocyte Activation; D008285:Major Histocompatibility Complex / Q000276:immunology; D051379:Mice; D008822:Mice, Transgenic; D013601:T-Lymphocytes / Q000502:physiology; D013950:Thymus Gland / Q000502:physiology