title: [The effect of noradrenaline on the neuronal reactions of the motor cortex evoked by conditional stimulation].
abstract: In chronic experiments on cats the influence of iontophoretic application of adrenomimetic ephedrin and beta-adrenoblocker obsidan (propranolol) on motor cortex neuron reactions following conditional stimuli was investigated under instrumental placing reaction. It was shown for a majority of neurons that the background impulse activity and reactions following conditional stimulation were suppressed by the influence of ephedrin and on the contrary were increased by obsidan application. It is concluded that there exists a consistent tonic suppressing influence of the noradrenergic system on background and evoked cortical neurons impulse activity in the natural state. It is supposed that noradrenergic influence temporal increase may serve as an important link in mechanisms of external inhibition during stress situations, aversive effects, and distractive external excitations.
authors: V M
authors: VM
authors: Storozhuk
authors: V V
authors: VV
authors: Stezhka
authors: S F
authors: SF
authors: Ivanova
mesh_terms: D000109:Acetylcholine / Q000008:administration & dosage / Q000494:pharmacology; D000161:Acoustic Stimulation; D000818:Animals; D002415:Cats; D003214:Conditioning, Classical / Q000187:drug effects* / Q000502:physiology; D004809:Ephedrine / Q000008:administration & dosage / Q000494:pharmacology; D007478:Iontophoresis; D008297:Male; D008839:Microelectrodes; D009044:Motor Cortex / Q000187:drug effects* / Q000502:physiology; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D009638:Norepinephrine / Q000494:pharmacology*; D011433:Propranolol / Q000008:administration & dosage / Q000494:pharmacology; D012701:Serotonin / Q000008:administration & dosage / Q000494:pharmacology
chemical_list: D012701:Serotonin; D011433:Propranolol; D004809:Ephedrine; D000109:Acetylcholine; D009638:Norepinephrine
vernacular_title: Vliianie noradrenalina na reaktsii neĭronov dvigatel'noĭ kory, vyzvannye uslovnoĭ stimuliatsieĭ.