Treatment with desmopressin in severe nocturnal enuresis in childhood.
A series of 22 patients with severe nocturnal enuresis were treated with desmopressin in a randomised double-blind cross-over study. Treatment with 20 and 40 micrograms was highly effective compared with placebo. No difference in dry nights was found between the 2 dosages. Desmopressin proved to be a safe and effective treatment.
Janknegt
R A
RA
Department of Urology, Groot Ziekengasthuis, The Netherlands.
Smans
A J
AJ
D000293:Adolescent; D001835:Body Weight / Q000187:drug effects; D002648:Child; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D004775:Enuresis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male
D003894:Deamino Arginine Vasopressin