title: Human neuroblastoma cells in culture: a model for neuronal cell differentiation and function.
abstract: The human neuroblastoma cell line, SH-SY5Y, differentiates into neuron-like cells according to morphological, biochemical and functional criteria when treated with biologically active phorbol-esters. The differentiated phenotype is described and alterations in proto-oncogene expression in connection with growth control and differentiation are presented and discussed.
authors: Department of Pathology, University Hospital, University of Uppsala, Sweden.
authors: S
authors: S
authors: Påhlman
authors: S
authors: S
authors: Mamaeva
authors: G
authors: G
authors: Meyerson
authors: M E
authors: ME
authors: Mattsson
authors: C
authors: C
authors: Bjelfman
authors: E
authors: E
authors: Ortoft
authors: U
authors: U
authors: Hammerling
mesh_terms: D002454:Cell Differentiation / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D009447:Neuroblastoma / Q000473:pathology*; D009474:Neurons / Q000502:physiology*; D000090063:Proto-Oncogene Mas; D014407:Tumor Cells, Cultured / Q000473:pathology*