Effect of acute burn trauma on reticuloendothelial system phagocytic activity in rats. II: Comparison of uptake of radiolabelled colloid and bacteria.
The uptake of radiolabelled colloid or bacteria was compared in normal rats and animals subjected to acute burn trauma. The uptake of colloid by the liver was unaffected by burn trauma, but uptake of the labelled bacteria was reduced. Spleen uptake of both colloid and bacteria was reduced by burn trauma while lung uptake was increased. These data are consistent with the hypothesis that acute burn trauma alters reticuloendothelial system phagocytic activity in the rat towards both inert particles and live bacteria.
Trop
M
M
Department of Pediatrics, Massachusetts General Hospital, Boston.
Schiffrin
E J
EJ
Callahan
R J
RJ
Strauss
H W
HW
Carter
E A
EA
D000208:Acute Disease; D000818:Animals; D002056:Burns / Q000378:metabolism*; D004195:Disease Models, Animal; D004926:Escherichia coli / Q000378:metabolism*; D005260:Female; D008099:Liver / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D012157:Mononuclear Phagocyte System / Q000378:metabolism*; D010587:Phagocytosis / Q000502:physiology*; D051381:Rats; D013154:Spleen / Q000378:metabolism; D013671:Technetium Tc 99m Sulfur Colloid / Q000378:metabolism*
D013671:Technetium Tc 99m Sulfur Colloid