title: [Atropine resistance and its significance in the selection of the method of surgical treatment of duodenal ulcer].
abstract: Medical vagotomy with atropine allows two types of patients with duodenal ulcer to be distinguished--atropine-resistant and atropine-sensitive. A complicated course of the disease, high values of nocturnal gastric secretion before the operation, and positive Hollander's insulin test after vagotomy are encountered most frequently in atropine-resistant patients. The values of gastrin are significantly higher in these patients than in atropine sensitive patients. In 3-year follow-up periods, recurrence of the ulcer after vagotomy was revealed in 6.5% of atropine-resistant patients but in none of the atropine sensitive patients. Medical vagotomy with consideration for atropine sensitivity may be a reliable prognostic criterion in the choice of the operative intervention in patients with duodenal ulcer.
authors: A I
authors: AI
authors: Nechaĭ
authors: A V
authors: AV
authors: Karachunov
authors: K N
authors: KN
authors: Movchan
authors: V K
authors: VK
authors: Zuev
authors: G N
authors: GN
authors: Ivanov
authors: Iu N
authors: IuN
authors: Fokin
mesh_terms: D001285:Atropine / Q000494:pharmacology*; D004351:Drug Resistance; D004381:Duodenal Ulcer / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D005744:Gastric Acid / Q000378:metabolism*; D005745:Gastric Acidity Determination; D005753:Gastric Mucosa / Q000187:drug effects / Q000378:metabolism*; D006801:Humans; D011379:Prognosis; D011706:Pyloric Antrum / Q000294:innervation / Q000601:surgery*; D013268:Stimulation, Chemical; D014628:Vagotomy / Q000379:methods*
chemical_list: D001285:Atropine
vernacular_title: Atropinorezistentnost'i ee znachenie v vybore metoda khirurgicheskogo lecheniia bol'nykh iazvoĭ dvenadtsatiperstnoĭ kishki.