[Effect of dioxidine on extracellular proteins and enzymes in Staphylococcus aureus].
Dioxidine++-induced changes were shown to occur in the protein composition of the cells of Staphylococcus aureus. The most significant damages were observed in the composition of exoproteins. Dioxidine++ had a specific inhibitory effect on intracellular nuclease, which was accompanied by a decrease in virulence and disorders in the toxin formation.
Fadeeva
N I
NI
Degtiareva
I N
IN
Fominova
A N
AN
Degteva
G K
GK
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000378:metabolism*; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D003851:Deoxyribonucleases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D066298:In Vitro Techniques; D008565:Membrane Proteins / Q000378:metabolism*; D010447:Peptide Hydrolases / Q000378:metabolism*; D011810:Quinoxalines / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D008565:Membrane Proteins; D011810:Quinoxalines; C001077:dioxidine; D003851:Deoxyribonucleases; D010447:Peptide Hydrolases
Deĭstvie dioksidina na vnekletochnye belki i fermenty Staphylococcus aureus.