[The applicability of the concept of morpho-physiologic metabolic factors to the modification of the distribution of 239Pu deposited in the respiratory organs].
At the stage of intensive resorption of plutonium from lungs to blood the competitive per os administration of an iron preparation increased plutonium excretion from blood. As a result, soft tissues were enriched with plutonium at an early stage of metabolism. However, at the end of the experiment (30 days) the radionuclide content of soft tissues dropped to control values. Simultaneously, the share of plutonium deposited in bone tissue decreased considerably and that of the radionuclide eliminated from the body increased throughout the entire period of observation.
Shvydko
N S
NS
Ivanova
N P
NP
Rushonik
S I
SI
D000284:Administration, Oral; D000818:Animals; D003666:Decontamination / Q000379:methods; D005243:Feces / Q000737:chemistry; D005290:Ferric Compounds / Q000008:administration & dosage*; D008168:Lung / Q000378:metabolism*; D008297:Male; D011005:Plutonium / Q000097:blood / Q000493:pharmacokinetics* / Q000652:urine; D051381:Rats; D014018:Tissue Distribution
D005290:Ferric Compounds; D011005:Plutonium; C025314:ferric citrate
Primenimost' kontseptsii morfofiziologicheskikh faktorov obmena k modifikatsii raspredeleniia popavshego v organy dykhaniia 239Pu.