[Transforming growth factor beta--a new type of inhibitor of proliferation of normal and tumor cells].
Based on literature data and on the results of the authors' investigation, the analysis of the transforming growth factor beta action as an inhibitor of proliferation of normal and tumor cells was carried out. The possible mechanisms of modulation of this action by other growth factors and by the cultivation conditions were considered. An attempt was made to determine the role of the transforming growth factor beta in the system of regulators of cell proliferation on the early stages of ontogenesis and during carcinogenesis.
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D000818:Animals; D002455:Cell Division / Q000187:drug effects*; D006801:Humans; D016212:Transforming Growth Factor beta / Q000494:pharmacology*; D014407:Tumor Cells, Cultured / Q000166:cytology / Q000187:drug effects*
D016212:Transforming Growth Factor beta
Transformiruiushchiĭ faktor rosta beta--novyĭ tip ingibitora proliferatsii normal'nykh i opukholevykh kletok.