Secondary metabolites by chemical screening. 7. I. Elaiophylin derivatives and their biological activities.
The synthesis and the biological activity of 34 acyl derivatives of elaiophylin (1) and 6 deglycosidation products were described. Especially the unsymmetric deglycosidation products 33, 38 and 40 and dimethyloctahydroelaiophylin (21) exhibited an activity against nematodes.
Hammann
P
P
Hoechst Aktiengesellschaft, Frankfurt/M., FRG.
Kretzschmar
G
G
Seibert
G
G
D000107:Acetylation; D000215:Acylation; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D018942:Macrolides; D015394:Molecular Structure
D000900:Anti-Bacterial Agents; D018942:Macrolides; C033279:elaiophylin