[A method for the experimental determination of the doses of antigen protecting 50% of animals from a series of doses of pathogenic material].
A new immunological regularity has been discovered mathematically. Proceeding from this regularity, a simple index characterizing the pathological reactivity of animals has been proposed and a new (universal) method for the determination of the D50 of the antigen, i. e. doses protecting 50% of the animals receiving a series of doses of pathogenic material, has been developed and checked according to experimental data.
Kachevskiĭ
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D000818:Animals; D000941:Antigens / Q000008:administration & dosage* / Q000276:immunology; D003140:Communicable Disease Control; D003141:Communicable Diseases / Q000276:immunology*; D004306:Dose-Response Relationship, Immunologic; D007114:Immunization; D016018:Least-Squares Analysis; D013997:Time Factors
D000941:Antigens
Metodika éksperimental'nogo opredeleniia doz antigena, zashchishchaiushchikh 50% zhivotnykh ot serii doz patogennogo materiala.