"C" trigonocephaly syndrome: clinical variability and possibility of surgical treatment.
We report on 3 new cases of C trigonocephaly syndrome. In addition to the findings characteristic of this condition, one of the patients also had a large omphalocele. This patient was referred from a suburban hospital with a diagnosis of Down syndrome, stressing the fact that C syndrome is still under-recognized and underdiagnosed. Another patient was diagnosed at birth and immediately submitted to craniosynostectomy. A second operation was performed 7 months later resulting in normal brain growth and close to normal psychomotor development at 3 years, in contrast to the third patient, who was not treated surgically and was severely retarded at 4 years.
Lalatta
F
F
Seconda Clinica Pediatrica, Università di Milano, Italy.
Clerici Bagozzi
D
D
Salmoiraghi
M G
MG
Tagliabue
P
P
Tischer
C
C
Zollino
M
M
Di Rocco
C
C
Neri
G
G
Opitz
J M
JM
D000015:Abnormalities, Multiple; D002675:Child, Preschool; D003398:Craniosynostoses / Q000601:surgery*; D005260:Female; D006554:Hernia, Umbilical; D006801:Humans; D007231:Infant, Newborn; D008607:Intellectual Disability / Q000517:prevention & control*; D007558:Italy; D008297:Male; D012886:Skull / Q000002:abnormalities*; D013577:Syndrome