[Local use of leukotriene inhibitor--NDGA in psoriasis].
NDGA is known as an inhibitor of leukotrienes and may exert some effect on psoriatic lesion formation. The aim of the study was to test the influence of this drug on appearance of psoriatic plaques. 7 day application of 0.015% NDGA on psoriatic lesions under occlusion in 23 patients, gave some flattening of lesions as compared to controls. However, after finishing of application all the changes reappeared in previous form. We have never observed permanent beneficial effect in any patient.
Szmurło
A
A
Kliniki Dermatologicznej AM w Warszawie.
D000208:Acute Disease; D000279:Administration, Cutaneous; D006801:Humans; D020024:Leukotriene Antagonists; D009637:Masoprocol / Q000008:administration & dosage*; D009779:Occlusive Dressings; D011565:Psoriasis / Q000188:drug therapy*; D012008:Recurrence
D020024:Leukotriene Antagonists; D009637:Masoprocol
Miejscowe stosowanie inhibitora leukotrienów--NDGA w łuszczycy.