title: [Disorders of zinc transport through the ileal epithelium in vitamin A deficiency and ischemia].
abstract: By means of histochemical revealing of zinc and applying radioactive isotope 65Zn accumulation, absorption and distribution of cations of this metal in the mucous membrane of the iliac intestine have been studied in chicken, normal, at ischemia and at A-avitaminosis. An essential zinc-depositing ability is peculiar to coverings of mucus upon the intestine epithelium, and among intracellular components--to smooth endoplasmic reticulum. A-avitaminosis and especially ischemia result in increasing permeability of the apical part of the external membrane of epitheliocytes, in overloading of the latter with zinc cations, when they are introduced into the intestine, as well as in decreasing transepithelial transport of zinc. The changes mentioned are accompanied with certain disturbances in the barrier function of the intestinal epithelium.
authors.forename: Iu G
authors.initials: IuG
authors.lastname: Markov
authors.forename: N I
authors.initials: NI
authors.lastname: Berzin'
mesh_terms: D000818:Animals; D001692:Biological Transport; D002645:Chickens / Q000378:metabolism*; D002712:Chlorides / Q000493:pharmacokinetics*; D004195:Disease Models, Animal; D004848:Epithelium / Q000098:blood supply / Q000378:metabolism / Q000648:ultrastructure; D007082:Ileum / Q000098:blood supply / Q000378:metabolism* / Q000648:ultrastructure; D066298:In Vitro Techniques; D007511:Ischemia / Q000378:metabolism* / Q000473:pathology; D008854:Microscopy, Electron; D014802:Vitamin A Deficiency / Q000378:metabolism* / Q000473:pathology; D015032:Zinc / Q000493:pharmacokinetics*; D017967:Zinc Compounds
chemical_list: D002712:Chlorides; D017967:Zinc Compounds; C016837:zinc chloride; D015032:Zinc
vernacular_title: Narushenie transporta tsinka cherez épiteliĭ podvzdoshnoĭ kishki pri A-avitaminoze i ishemii.