title: [Pathological mechanism of spontaneous hemostasis in traumatic artery rupture].
abstract: In ruptures of arteries the spontaneous haemostasis was supposed to be induced by 'rolling' of the intima until now. Experiments with isolated arterial segments (human femoral artery) and in vivo with ovine femoral arteries could not show this mechanism as the reason for the spontaneous haemostasis. The structure of the adventitia and its typical behavior during rupture procedure explains better the 'sandglass formation' in arterial ruptures with fractures and dislocations. This is induced by a 'fingertrap'-mechanism of the adventitia. The adventitia is sealed by platelets, which show a direct interaction with the collagen fibers of the adventitia. The platelet thrombus is stabilized by fibrin.
authors.affiliation: Unfallchirurgische Klinik, Medizinischen Hochschule Hannover.
authors.forename: E
authors.initials: E
authors.lastname: Scola
mesh_terms: D000328:Adult; D000673:Amputation, Traumatic; D000818:Animals; D001134:Arm Injuries / Q000503:physiopathology; D001158:Arteries / Q000033:anatomy & histology / Q000293:injuries* / Q000502:physiology; D005260:Female; D005263:Femoral Artery / Q000033:anatomy & histology / Q000293:injuries / Q000502:physiology; D006487:Hemostasis; D006801:Humans; D008297:Male; D008875:Middle Aged; D012421:Rupture; D012756:Sheep
vernacular_title: Pathomechanismus des spontanen Gefässverschlusses bei traumatischer Arterienruptur.