The effects of graded exercise on plasma proenkephalin peptide F and catecholamine responses at sea level.
The purpose of this study was to evaluate the effects of graded treadmill exercise on plasma preproenkephalin peptide F immunoreactivity and concomitant catecholamine responses at sea level (elevation, 50 m). Few data exist regarding the sea-level responses of plasma peptide F immunoreactivity to exercise. thirty-five healthy men performed a graded exercise test on a motor-driven treadmill at the relative exercise intensities of 25, 50, 75, and 100% of maximum oxygen consumption (VO2max). Significant (P less than 0.05) increases above rest were observed for plasma peptide F immunoreactivity and norepinephrine at 75 and 100% of the VO2 max and at 5 min into recovery. Significant increases in plasma epinephrine were observed at 75 and 100% of VO2max. Whole blood lactate significantly increased above resting values at 50, 75, and 100% of the VO2max and at 5 min into recovery. These data demonstrate that exercise stress increases plasma peptide F immunoreactivity levels at sea level. While the exercise response patterns of peptide F immunoreactivity are similar to catecholamines and blood lactate responses, no bivariate relationships were observed. These data show that sea-level response patterns to graded exercise are similar to those previously observed at moderate altitude (elevation, 2200 m).
Kraemer
W J
WJ
Exercise Physiology Division, U.S. Army Research Institute of Environmental Medicine, Natick, MA 01760.
Dziados
J E
JE
Gordon
S E
SE
Marchitelli
L J
LJ
Fry
A C
AC
Reynolds
K L
KL
D000328:Adult; D004744:Enkephalin, Methionine / Q000031:analogs & derivatives* / Q000097:blood; D004837:Epinephrine / Q000097:blood*; D015444:Exercise / Q000502:physiology*; D006801:Humans; D007700:Kinetics; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D008297:Male; D009638:Norepinephrine / Q000097:blood*; D010101:Oxygen Consumption; D011498:Protein Precursors / Q000097:blood*
D007773:Lactates; D011498:Protein Precursors; D019344:Lactic Acid; D004744:Enkephalin, Methionine; C036452:peptide F; D009638:Norepinephrine; D004837:Epinephrine