[Contribution of proteolytic enzymes to the knowledge of biologic functions of fibronectin].
Proteolytic enzymes have been used to separate and analyze the fibronectin sequences responsible for the multiple interactions between fibronectin and collagens, proteoglycans, cell surfaces, etc. The location of these sequences on the molecule subunits has also been determined. This short article summarizes these results as well as future prospects.
Labat-Robert
J
J
Laboratoire de Biochimie du Tissu Conjonctif, UA CNRS 1174, Faculté de Médecine, Créteil, France.
D002462:Cell Membrane / Q000378:metabolism; D003094:Collagen / Q000378:metabolism; D004347:Drug Interactions; D005337:Fibrin / Q000378:metabolism; D005353:Fibronectins / Q000378:metabolism*; D006493:Heparin / Q000378:metabolism; D009369:Neoplasms / Q000378:metabolism; D010446:Peptide Fragments / Q000378:metabolism; D010447:Peptide Hydrolases / Q000378:metabolism*
D005353:Fibronectins; D010446:Peptide Fragments; D005337:Fibrin; D006493:Heparin; D003094:Collagen; D010447:Peptide Hydrolases
Apport des enzymes protéolytiques à la connaissance des fonctions biologiques de la fibronectine.