[Lipoproteins, elastases and atherogenesis].
Increased lipid deposition and fragmentation of elastic lamellae are main events in atherogenesis. Relationships between lipoproteins and elastase can exist: i) interactions between lipoproteins and arterial wall cells from mesenchymal or inflammatory origin can modulate the expression and secretion of elastase; ii) such neutral proteases can degrade protein constituents of lipoproteins, and modify their physical and biological properties.
Hornebeck
W
W
URA 1174, CNRS, Faculté de Médecine, Hôpital Henri-Mondor, Créteil, France.
D000818:Animals; D001161:Arteriosclerosis / Q000378:metabolism*; D004347:Drug Interactions; D005347:Fibroblasts / Q000378:metabolism; D006801:Humans; D007962:Leukocytes / Q000378:metabolism; D008074:Lipoproteins / Q000378:metabolism*; D009130:Muscle, Smooth / Q000378:metabolism; D010196:Pancreatic Elastase / Q000378:metabolism*; D051381:Rats
D008074:Lipoproteins; D010196:Pancreatic Elastase
Lipoprotéines, élastases et athérogenèse.