title: Antimicrobial properties of N-carboxybutyl chitosan.
abstract: N-Carboxybutyl chitosan, a modified chitin of crustacean origin, displayed inhibitory, bactericidal, and candidacidal activities when tested against 298 cultures of various pathogens. Examination by electron microscopy showed that microbial cells exposed to N-carboxybutyl chitosan underwent marked morphological alterations. The data are of importance in defining the suitability of N-carboxybutyl chitosan as a wound dressing.
authors.affiliation: Institute of Biochemistry, Faculty of Medicine, University of Ancona, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Muzzarelli
authors.forename: R
authors.initials: R
authors.lastname: Tarsi
authors.forename: O
authors.initials: O
authors.lastname: Filippini
authors.forename: E
authors.initials: E
authors.lastname: Giovanetti
authors.forename: G
authors.initials: G
authors.lastname: Biagini
authors.forename: P E
authors.initials: PE
authors.lastname: Varaldo
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000648:ultrastructure; D002473:Cell Wall / Q000187:drug effects; D002686:Chitin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D048271:Chitosan
chemical_list: D000900:Anti-Bacterial Agents; C067347:N-carboxybutyl chitosan; D002686:Chitin; D048271:Chitosan