title: [Germinal tumors of the testis. A caseload and review of the literature].
abstract: Between 1974 and 1988, 35 testicle germinal tumours, 16 seminomas and 19 non seminomas, were studied. Mean age in seminoma cases was 34 years and 26 in non seminoma cases; the former were mainly presented as located stages at the time of diagnosis (75%) while the latter were, on the contrary, mostly stages II and III. Following orchiectomy, all histologically pure seminomas received radiotherapy with the exception of two cases. All of them are presently free from the disease with an average follow-up of 2.8 years (range 0.5-5 Yr.) Radiotherapy continues to be proposed as first choice therapeutic action for siminomas in located stages, although we do not disagree with other more conservative possibilities. In the non seminoma group, all three patients diagnosed in stage I were clinically controlled without supplementary therapy, two of them having a recurrence during the first year of follow-up, but currently free of the disease after chemotherapy and surgery of residual masses. Of the three non seminoma patients in stage II, with negative post-orchiectomy markers, two underwent lymphadenectomy and the other one only chemotherapy. In the remaining group of non seminoma patients, and always after an orchiectomy, chemotherapy was performed as first choice therapy, although rescue lymphadenectomy was required in eight cases. Chemotherapy schemes with cisplatin have relegated to a second level any other therapy for the non seminoma patients. The excellent response and reduction of side effects allow the adoption of more conservative attitudes. This paper explains our retrospective study and, following a wide review of exiting literature, discussed any conflictive prognostic and therapeutic items.
authors.affiliation: Servicio Urologia Hospital Príncipes de España, L'Hospitalet, Barcelona.
authors.forename: J
authors.initials: J
authors.lastname: Armora Mani
authors.forename: L
authors.initials: L
authors.lastname: Riera Canals
authors.forename: E
authors.initials: E
authors.lastname: Franco Miranda
authors.forename: M
authors.initials: M
authors.lastname: Pérez Céspedes
authors.forename: M A
authors.initials: MA
authors.lastname: López Costea
authors.forename: N
authors.initials: N
authors.lastname: Serrallach Mila
authors.forename: F
authors.initials: F
authors.lastname: Cardenal
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016063:Blood Loss, Surgical; D003131:Combined Modality Therapy; D004407:Dysgerminoma / Q000628:therapy*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013736:Testicular Neoplasms / Q000628:therapy*
vernacular_title: Tumores germinales de testículo. Casuística y revisión bibliográfica.