[The prostacyclin-thromboxane system and the functional properties of the thrombocytes in patients of different ages with ischemic heart disease].
A study is presented of the reactions of prostacyclin-thromboxane system and functions of thrombocytes to physical loads inducing myocardial ischemia in patients with ischemic heart disease of different age groups. Examined were 62 patients with stable stenocardia of the II and III functional classes. Age of the patients: from 44 to 60 years. It was found that the elderly showed deterioration of the prostacyclin-thromboxane imbalance and a reduction of the sensitivity of thrombocytes to prostacyclin. The should be considered in instituting prolonged drug treatment.
Ermakovich
I I
II
Ladnyĭ
A I
AI
Volkov
V I
VI
Tseluĭko
V I
VI
D000328:Adult; D000375:Aging / Q000097:blood*; D000787:Angina Pectoris / Q000097:blood; D001792:Blood Platelets / Q000502:physiology*; D003327:Coronary Disease / Q000097:blood*; D011464:Epoprostenol / Q000097:blood*; D005080:Exercise Test; D006801:Humans; D008297:Male; D008875:Middle Aged; D005082:Physical Exertion / Q000502:physiology; D013931:Thromboxanes / Q000097:blood*
D013931:Thromboxanes; D011464:Epoprostenol
Sostoianie prostatsiklin-tromboksanovoĭ sistemy i funktsional'nye svoĭstva trombotsitov u bol'nykh ishemicheskoĭ bolezn'iu serdtsa razlichnogo vozrasta.