Sclerema neonatorum and subcutaneous fat necrosis of the newborn in the same infant.
Sclerema neonatorum (SN) is a rare disease of the newborn characterised by diffuse hardening of the subcutaneous adipose tissue. The condition is distinct from the localised violacious nodules observed in subcutaneous fat necrosis of the newborn (SCFN). Both conditions were diagnosed within the first 2 weeks of life in the same infant. SN and SCFN are unusual conditions in the newborn, the former usually associated with a severe clinical illness, following delivery or major surgery. The skin lesions of these two conditions are distinct and do not usually occur simultaneously. SN is associated with a poor prognosis.
Jardine
D
D
Department of Paediatrics, Royal Free Hospital, London, UK.
Atherton
D J
DJ
Trompeter
R S
RS
D000273:Adipose Tissue / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012593:Sclerema Neonatorum / Q000150:complications* / Q000473:pathology; D012867:Skin