title: [Cow's milk protein intolerance: evaluation of immunological markers. A preliminary study].
abstract: Cow's milk protein intolerance (CMPI) is recognised as an important cause of protean symptoms in infants. There are no tests with enough specificity and sensibility to set up a diagnostic assay. We carried out preliminary study on children suffering from CMPI with the following aims: a) to ascertain the importance of the variation in circulating antibodies to cow's milk proteins in CMPI, b) to establish a useful screening tool to diagnose CMPI. Seventy-four subjects (s.) were studied and divided into four diagnostic groups as follows: Six s. (3 M, 3 F) suffering from CMPI mean age 4.8 +/- 3.9 months, assuming a diet containing cow's milk: I group. Eleven s. (O M, 7 F) suffering from CMPI mean age 7.8 +/- 4.6 months, assuming a cow's milk free diet, for several months (mean 4.5 +/- 1.5): II group. Nine s. (5 M, 4 F) suffering from enteropathies not cow's milk correlated, mean age 18.5 +/- 10.6 months, assuming a diet containing cow's milk: III group. Fourty-eight healthy s. (24 M, 24 F), mean age 10.5 +/- 4.3 months, assuming a diet containing cow's milk.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Istituto di Clinica Pediatrica, Università di Modena, Italia.
authors.forename: F
authors.initials: F
authors.lastname: Balli
authors.forename: F
authors.initials: F
authors.lastname: Del Bianco
authors.forename: A
authors.initials: A
authors.lastname: Savoini
authors.forename: P
authors.initials: P
authors.lastname: Bertolani
mesh_terms: D002364:Caseins / Q000276:immunology; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005470:Fluorometry; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007223:Infant; D007231:Infant, Newborn; D007768:Lactalbumin / Q000276:immunology; D007782:Lactoglobulins / Q000276:immunology*; D008297:Male; D016269:Milk Hypersensitivity / Q000175:diagnosis* / Q000276:immunology; D008894:Milk Proteins / Q000009:adverse effects* / Q000276:immunology
chemical_list: D002364:Caseins; D007074:Immunoglobulin G; D007782:Lactoglobulins; D008894:Milk Proteins; D007768:Lactalbumin
vernacular_title: Intolleranza alle proteine del latte vaccino: valutazione di alcuni marcatori immunologici. Studio preliminare.