title: Preparation and antimicrobial activity of 1-arylazo-3,4,6,7,8,9-hexahydroquinolizines.
abstract: A set of 1-(R-arylazo)-3,4,6,7,8,9-hexahydroquinolizines, bearing different substituents on the benzene ring, were prepared and tested for antimicrobial activity. These compounds exhibit only a very weak activity against gram-positive and gram-negative bacteria, but are fairly active against several Candida species and other yeast-like fungi.
authors.affiliation: Istituto Chimico Farmaceutico, Università di Milano, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Sparatore
authors.forename: C C
authors.initials: CC
authors.lastname: Boido
authors.forename: V
authors.initials: V
authors.lastname: Boido
authors.forename: F
authors.initials: F
authors.lastname: Sparatore
authors.forename: E
authors.initials: E
authors.lastname: Debbia
authors.forename: A P
authors.initials: AP
authors.lastname: Schito
mesh_terms: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001391:Azo Compounds / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D009643:Norfloxacin / Q000494:pharmacology; D011807:Quinolizines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013056:Spectrophotometry, Ultraviolet; D015003:Yeasts / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D001391:Azo Compounds; D011807:Quinolizines; D009643:Norfloxacin