i(12p) in a malignant ovarian tumor.
We have found one or more copies of i(12p) in an ovarian germ cell tumor, histologically a yolk sac tumor. This chromosome marker is characteristically associated with germ cell tumors in males. This report indicates that further investigation is necessary to establish the role of the i(12p) marker in the pathogenesis of germ cell tumors also in females.
Speleman
F
F
Department of Medical Genetics, University Hospital Gent, Belgium.
De Potter
C
C
Dal Cin
P
P
Mangelschots
K
K
Ingelaere
H
H
Laureys
G
G
Benoit
Y
Y
Leroy
J
J
Van Den Berghe
H
H
D002675:Child, Preschool; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002881:Chromosomes, Human, Pair 12; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D008649:Mesonephroma / Q000235:genetics* / Q000473:pathology; D010051:Ovarian Neoplasms / Q000235:genetics* / Q000473:pathology
D005819:Genetic Markers