Aspartate kinase as an enzyme able to phosphorylate aspartate in the nervous system. Immunocytochemical study.
An immunohistochemical method using antibodies against bacterial aspartate kinase has been carried out in order to localize this enzyme in the cerebellar cortex of rat. The results obtained with light microscope have demonstrated a positive immunoreaction in both the granular and molecular layers. Electron microscopic observation has also revealed the reaction in several dendrites, axons and myelinated fibers. These facts lead us to think that aspartate kinase could be involved in the phosphorylation of aspartate in the nervous tissue.
Arenas-Díaz
G
G
Laboratorio Inmunocitoquímica, Universidad Católica de Valparaíso, Chile.
Martínez-Rodríguez
R
R
D000818:Animals; D001222:Aspartate Kinase / Q000378:metabolism*; D001224:Aspartic Acid / Q000378:metabolism; D002525:Cerebellar Cortex / Q000378:metabolism*; D007150:Immunohistochemistry; D008297:Male; D010766:Phosphorylation; D051381:Rats; D011919:Rats, Inbred Strains
D001224:Aspartic Acid; D001222:Aspartate Kinase