title: Improvement of pneumonia and arthritis in Felty's syndrome by treatment with granulocyte-macrophage colony-stimulating factor (GM-CSF).
abstract: A 63-year old man with Felty's syndrome and pneumonia of unknown origin was treated with GM-CSF. Granulocyte counts increased and arthritis-related symptoms improved under GM-CSF. Pneumonia was treated effectively with antibiotics only during or after GM-CSF application. This suggests, that antibiotic-resistant infections can be treated effectively in patients with Felty's syndrome when granulocyte counts are raised by GM-CSF.
authors.affiliation: Department of Internal Medicine, Free University of Berlin, Federal Republic of Germany.
authors.forename: A S
authors.initials: AS
authors.lastname: Lübbe
authors.forename: N
authors.initials: N
authors.lastname: Schwella
authors.forename: H
authors.initials: H
authors.lastname: Riess
authors.forename: D
authors.initials: D
authors.lastname: Huhn
mesh_terms: D005258:Felty Syndrome / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000627:therapeutic use*; D006098:Granulocytes / Q000473:pathology; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000097:blood / Q000150:complications / Q000188:drug therapy*
chemical_list: D016178:Granulocyte-Macrophage Colony-Stimulating Factor