title: [The changes of serum gamma-Sm level in acute prostatitis].
abstract: gamma-Sm, the specific antigen of the prostate, is useful for the diagnosis and following-up of prostatic cancer. It is recognized as the tumor marker. The serum gamma-Sm is increased in some cases of acute prostatitis. We evaluated the serum gamma-Sm in patients with acute prostatitis. Serum gamma-Sm, PAP, CRP and WBC count were measured before treatment with antibiotics and 3 to 5 days and 1 week thereafter. In the acute phase of inflammation (before treatment) serum gamma-Sm increased in 62.5% of the cases. Then it decreased quickly and was within the normal range 3 to 5 days later. This change of serum gamma-Sm is similar to that of WBC count, fever and urinalysis. But the decrease of serum gamma-Sm is earlier than that of CRP. PAP does not increase in any phase of inflammation. It suggests that the serum gamma-Sm reflects cell damages of the prostatic gland or increased permeability due to prostatitis.
authors.affiliation: Department of Urology, Yokosuka Hokubu Kyosai Hospital.
authors.forename: K
authors.initials: K
authors.lastname: Fujimoto
authors.forename: T
authors.initials: T
authors.lastname: Kodaira
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D014408:Biomarkers, Tumor / Q000032:analysis; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000175:diagnosis; D029584:Prostatic Secretory Proteins; D011472:Prostatitis / Q000175:diagnosis*; D011506:Proteins / Q000032:analysis*; D029589:Seminal Plasma Proteins
chemical_list: D014408:Biomarkers, Tumor; D029584:Prostatic Secretory Proteins; D011506:Proteins; D029589:Seminal Plasma Proteins; C043076:beta-microseminoprotein