title: Two new natural azafluorene alkaloids and a cytotoxic aporphine alkaloid from Polyalthia longifolia.
abstract: The stem and stem bark of Polyalthia longifolia afforded the cytotoxic aporphine alkaloid liriodenine [1], as well as two aporphine alkaloids, noroliveroline [2] and oliveroline-beta-N-oxide [3] and three azafluorene alkaloids, darienine [4], polyfothine [6], and isooncodine [7], which are not bioactive. Polyfothine [6] and isooncodine [7] are new natural compounds.
authors.affiliation: School of Pharmacy, Kaohsiung Medical College, Taiwan, Republic of China.
authors.forename: Y C
authors.initials: YC
authors.lastname: Wu
authors.forename: C Y
authors.initials: CY
authors.lastname: Duh
authors.forename: S K
authors.initials: SK
authors.lastname: Wang
authors.forename: K S
authors.initials: KS
authors.lastname: Chen
authors.forename: T H
authors.initials: TH
authors.lastname: Yang
mesh_terms: D000470:Alkaloids / Q000302:isolation & purification* / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification*; D001060:Aporphines / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D004354:Drug Screening Assays, Antitumor; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010944:Plants / Q000032:analysis*
chemical_list: D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D001060:Aporphines; C067653:polyfothine; C067652:darienine; C067654:isooncodine; C026980:liriodenine