title: [The therapeutic effect of somofilin in bronchial asthma patients].
abstract: The sustained release theophylline drug Somophylline in capsules was applied in 21 asthmatic patients (12 women and 9 men), mean age 44.5 years in the course of 14 days in hospital conditions. The dose of the drug was 9-10 mg/kg body mass (24 h given in two equal doses in 12 h intervals). The effect was favourable in 17 patients (80.95%), weak--in 2 patients (9.52%) and no effect in 2 patients (9.52%). Somophylline is very well tolerated. The blood level remains in the therapeutic ranges during the treatment (about 10 micrograms/ml).
authors.forename: G
authors.initials: G
authors.lastname: Kosturkov
authors.forename: M
authors.initials: M
authors.lastname: Staneva
authors.forename: Zh
authors.initials: Zh
authors.lastname: Mileva
authors.forename: S
authors.initials: S
authors.lastname: Gerzilova
authors.forename: S
authors.initials: S
authors.lastname: Slavov
authors.forename: V
authors.initials: V
authors.lastname: Dimitrov
authors.forename: T
authors.initials: T
authors.lastname: Vŭlcheva
authors.forename: T
authors.initials: T
authors.lastname: Popov
mesh_terms: D000328:Adult; D000368:Aged; D000628:Aminophylline / Q000009:adverse effects / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy*; D002214:Capsules; D003692:Delayed-Action Preparations; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D002214:Capsules; D003692:Delayed-Action Preparations; D000628:Aminophylline
vernacular_title: Lecheben efekt na somofilin pri bolni ot bronkhialna astma.