title: Coincidence of risk factors and early carotid lesions, detected with modern ultrasound techniques.
abstract: Using a multichannel pulsed Doppler ultrasound device, studies of flow kinetics and vessel wall motility at the beginning of the internal carotid artery (ICA) were carried out. Regarding the results of special computer analysis in 120 subjects with healthy vessels, a dilation of the proximal ICA and a decrease in mean flow velocity which was related to the age of the individual could be assessed. Depending on age and risk factors, wall dyskinetics and turbulences in the dorso-lateral part of the vessel could be detected and confirmed by the flow imaging method. In a second study of 100 subjects (between 15 and 50 years of age) without risk factors, an age-dependent dilatation of ICA could be diagnosed by high resolution Duplex system. In the same study an increased incidence of wall thickening and plaques formation in the dilated area of the ICA was observed. The study of 234 patients with different risk factors showed that hypertonics developed an extended dilatation of the ICA and that wall thickening and plaque formation occurred significantly more often than in other risk groups.
authors.affiliation: Abteilung für Klinische Hämostaseologie, Angiologische Ambulanz, Universitätskliniken Homburg/Saar.
authors.forename: P
authors.initials: P
authors.lastname: Scheffler
authors.forename: G
authors.initials: G
authors.lastname: Leipnitz
authors.forename: C
authors.initials: C
authors.lastname: Bender
authors.forename: D
authors.initials: D
authors.lastname: de la Hamette
authors.forename: F
authors.initials: F
authors.lastname: Kettenbaum
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001783:Blood Flow Velocity / Q000502:physiology; D002545:Brain Ischemia / Q000000981:diagnostic imaging*; D002339:Carotid Arteries / Q000000981:diagnostic imaging; D002340:Carotid Artery Diseases / Q000000981:diagnostic imaging*; D003251:Constriction, Pathologic / Q000000981:diagnostic imaging; D004453:Echoencephalography / Q000295:instrumentation*; D005260:Female; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged