title: [Sex chromosome aberrations in patients with menstruation disorders].
abstract: We studied 150 women with primary/secondary amenorrhea and/or oligomenorrhea; in 61 cases we found an abnormal karyotype (i.e. 40.7%): 51 cases in the first group of 110 patients with amenorrhea (i.e. 46%) and 10 cases in the second group of 40 patients with oligomenorrhea and/or secondary amenorrhea (i.e. 25%). The chromosome aberrations we found consisted in X aneuploidy, male karyotype and the different structural changes as mono- and dicentric X isochromosomes, dicentric, ring, deleted or inverted X chromosomes. Our results suggest a cytogenetic examination in patients with primary amenorrhea as well as in patients with oligomenorrhea and/or amenorrhea secundaria.
authors.affiliation: Service de Génétique Clinique Académie de Médecine de Bialystok, Pologne.
authors.forename: A T
authors.initials: AT
authors.lastname: Midro
authors.forename: B
authors.initials: B
authors.lastname: Panasiuk
authors.forename: J
authors.initials: J
authors.lastname: Radwan
authors.forename: I
authors.initials: I
authors.lastname: Sipowicz
authors.forename: B
authors.initials: B
authors.lastname: Jaworowska
authors.forename: E
authors.initials: E
authors.lastname: Korsak
mesh_terms: D000293:Adolescent; D000328:Adult; D000568:Amenorrhea / Q000209:etiology / Q000235:genetics*; D002648:Child; D002869:Chromosome Aberrations / Q000235:genetics*; D005260:Female; D006801:Humans; D007621:Karyotyping; D008875:Middle Aged; D009839:Oligomenorrhea / Q000209:etiology / Q000235:genetics*; D012730:Sex Chromosomes; D014424:Turner Syndrome / Q000150:complications / Q000235:genetics; D014960:X Chromosome; D014998:Y Chromosome
vernacular_title: Les aberrations des chromosomes sexuels chez les patientes présentant des troubles de la menstruation.