[The general biological principles of the development of complications in the postoperative period of acute peritonitis and the expediency of hemosorption].
The dynamic study of a number of clinical and laboratory findings in 107 patients with acute peritonitis have shown that with the current complex infusion therapy the onset of postoperative complications is to a great extent mediated by high toxin level--medium molecular mass polypeptide, inhibiting the processes of protein synthesis and consequently causing changes in the relationship between adaptation compensatory reactions, which demonstrates the necessity of additional active detoxicating therapy, i.e. hemosorption (HS). HS was performed to 126 patients and its efficacy in pronounced toxemia was established. The data obtained make it possible to consider HS as an effective means preventing the onset of postoperative complications in acute peritonitis.
Poluéktov
L V
LV
Reĭs
B A
BA
Red'kin
Iu V
IuV
Konvaĭ
V D
VD
Ktenidi
L I
LI
Sen'ko
V P
VP
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D006464:Hemoperfusion; D006801:Humans; D008875:Middle Aged; D010538:Peritonitis / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology* / Q000628:therapy; D014118:Toxins, Biological / Q000096:biosynthesis*
D014118:Toxins, Biological
Obshchebiologicheskie zakonomernosti formirovaniia oslozheniĭ v posleoperatsionnom periode ostrogo peritonita i tselesoobraznost' gemosorbtsii.