[Mutagenesis, directed by artificial oligonucleotide analogs. I. Participation of ribonucleotide fragments in DNA replication and repair].
The mutation system has been developed to study the mutagenic properties of modified oligonucleotide analogs. The mutagenic properties of oligonucleotides containing one ribonucleotide have been examined. The presence of a ribonucleotide is shown not to induce any mutations. But when the oligonucleotide induces two marker deletions detached by 6 nucleotides they may be repaired separately, in this case the deletion bordering with the ribonucleotide is predominantly repaired.
Petrenko
V A
VA
Kuz'micheva
G A
GA
Tat'kov
S I
SI
Krasnoborov
I I
II
Il'ichev
A A
AA
Baturina
I I
II
Maĭstrenko
V F
VF
Tsytovich
A V
AV
Dolinnaia
N G
NG
Shabarova
Z A
ZA
D001483:Base Sequence; D004260:DNA Repair; D004261:DNA Replication; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D009841:Oligonucleotides / Q000235:genetics*; D012265:Ribonucleotides / Q000235:genetics*
D009841:Oligonucleotides; D012265:Ribonucleotides
Mutagenez, napravlennyĭ neprirodnymi analogami oligonukleotidov. I. Uchastie ribonukleotidnykh zven'ev v reparatsii i replikatsii DNK.