[Clinical and experimental control of optimal therapy in epilepsy].
On the basis of a psychopathologically calibrated battery of tests, the effects of four drugs commonly prescribed for the alleviation of epilepsy (Valproinat, Carbamazepin, Diphenylhydantoin, and Primidon) were examined before and after optimisation of therapy. The positive psychotropic effect of Valproinat and Carbamazepin, and probably also of Diphenylhydantoin, consists in the acceleration of the psychic and motor rate and in the reduction of viscosity and perseveration.
Ruser
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Lehrstuhl Psychiatrie, Bereichs Medizin Charité, Humboldt-Universität zu Berlin.
D000927:Anticonvulsants / Q000008:administration & dosage* / Q000009:adverse effects; D002220:Carbamazepine / Q000008:administration & dosage / Q000009:adverse effects; D004359:Drug Therapy, Combination; D004827:Epilepsy / Q000188:drug therapy* / Q000523:psychology; D006801:Humans; D019965:Neurocognitive Disorders / Q000188:drug therapy* / Q000523:psychology; D009483:Neuropsychological Tests; D010672:Phenytoin / Q000008:administration & dosage / Q000009:adverse effects; D011324:Primidone / Q000008:administration & dosage / Q000009:adverse effects; D019966:Substance-Related Disorders / Q000175:diagnosis / Q000523:psychology; D014635:Valproic Acid / Q000008:administration & dosage / Q000009:adverse effects
D000927:Anticonvulsants; D011324:Primidone; D002220:Carbamazepine; D014635:Valproic Acid; D010672:Phenytoin
Klinische und experimentell kontrollierte Therapieoptimierung bei Epilepsie.