[Dietary protein as a modulator of the activity of enzymes metabolizing xenobiotics. Epoxide hydrolase].
Growing male rats received rations containing 5.18 and 33% of protein during 2 months. In contrast to other microsomal enzymes, epoxide hydrolase activity was maximal in the liver of the animals which received the ration with 5% of protein, and minimal--with 18% of protein. Epoxide hydrolase in the liver of rats that received the rations with 5 and 18% of protein showed equally expressed capacity for induction and activation in vivo and in vitro.
Tutel'ian
V A
VA
Kravchenko
L V
LV
Kuz'mina
E E
EE
D000818:Animals; D004044:Dietary Proteins / Q000494:pharmacology*; D004851:Epoxide Hydrolases / Q000378:metabolism*; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains; D015262:Xenobiotics
D004044:Dietary Proteins; D015262:Xenobiotics; D004851:Epoxide Hydrolases
Pishchevoĭ belok kak moduliator aktivnosti fermentov, metaboliziruiushchikh ksenobiotiki. Epoksidgidrolaza.