[The chronic action of lead on the vascular system: the problem of ecological pathology].
Problem of chronic effects of the lead (L) on the cardiovascular system is presented from the viewpoint of the ecological pathology. The review summarizes: sources of L in the environment, industries in which L is widely used in the technological process, occupations in which L intoxication is possible, routes of L penetration into the organism and the organs of its accumulation, mechanisms and variants of chronic L effects on the vascular system. In case of chronic L toxicity the vessels of various organs and system are affected; the pathologic process is of a vasculitis or arteriosclerosis type and is predominantly observed in the arteries of small and mean caliber. The mechanisms of vascular L effect is not sufficiently studied.
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D000818:Animals; D001808:Blood Vessels / Q000187:drug effects* / Q000473:pathology; D002318:Cardiovascular Diseases / Q000139:chemically induced / Q000473:pathology; D002908:Chronic Disease; D004463:Ecology; D004782:Environmental Health; D004785:Environmental Pollutants; D006801:Humans; D007854:Lead / Q000009:adverse effects* / Q000633:toxicity; D007855:Lead Poisoning / Q000209:etiology / Q000473:pathology; D009784:Occupational Diseases / Q000139:chemically induced / Q000473:pathology
D004785:Environmental Pollutants; D007854:Lead
Khronicheskoe vozdeĭstvie svintsa na sosudistuiu sistemu: problema ékologicheskoĭ patologii.