Smooth lipopolysaccharide of Salmonella adelaide has an atypical Salmonella Ra core.
Two wild isolates as well as two laboratory strains of Salmonella adelaide obtained from different geographical areas failed to react with a monoclonal antibody directed against the terminal alpha-1,2-linked N-acetylglucosamine residue of the outer core of Salmonella lipopolysaccharide (LPS). This finding was confirmed by the lack of reactivities of Salmonella Ra LPS with S. adelaide antiserum or of S. adelaide R oligosaccharide with Salmonella Ra serum. Furthermore, S. adelaide proved to be resistant to lysis by phage FO1, which binds to a receptor also believed to involve the terminal alpha-1,2-linked N-acetylglucosamine of the Salmonella R oligosaccharide. These results suggest that the outer core structure of S. adelaide LPS may be different from that of S. typhimurium and other Salmonella strains.
Tsang
R S
RS
Department of Microbiology, University of Hong Kong.
Schlecht
S
S
D000911:Antibodies, Monoclonal / Q000276:immunology; D000937:Antigen-Antibody Reactions / Q000276:immunology; D002467:Cell Nucleus / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D066298:In Vitro Techniques; D008070:Lipopolysaccharides / Q000276:immunology*; D012475:Salmonella / Q000166:cytology* / Q000276:immunology
D000911:Antibodies, Monoclonal; D008070:Lipopolysaccharides