title: [Biotechnological and biomedical aspects of production and study of metal cation-phospholipid complexes].
abstract: Problems relating to the technology of a phospholipid preparation from natural materials, liposome production, and studies into the mechanisms of interaction between metal (trace elements) cations and model bilayer lipid membranes are discussed. The proposed technology of extraction allows for preparation of phospholipids utilizable for liposome formation. The cation specificity of lipid bilayers is found to be determined by the presence of anionic phosphate adsorption sites on their surface.
authors.forename: A M
authors.initials: AM
authors.lastname: Omel'chenko
authors.forename: B A
authors.initials: BA
authors.lastname: Bovykin
authors.forename: O I
authors.initials: OI
authors.lastname: Shkola
authors.forename: F
authors.initials: F
authors.lastname: Ryshka
authors.forename: M
authors.initials: M
authors.lastname: Sosada
mesh_terms: D001709:Biotechnology / Q000379:methods*; D002412:Cations; D004337:Drug Carriers; D008051:Lipid Bilayers; D008081:Liposomes / Q000138:chemical synthesis*; D008670:Metals / Q000008:administration & dosage / Q000138:chemical synthesis*; D010713:Phosphatidylcholines / Q000008:administration & dosage / Q000302:isolation & purification*; D013678:Technology, Pharmaceutical / Q000379:methods*; D014455:Ukraine
chemical_list: D002412:Cations; D004337:Drug Carriers; D008051:Lipid Bilayers; D008081:Liposomes; D008670:Metals; D010713:Phosphatidylcholines
vernacular_title: Biotekhnologicheskie i biomeditsinskie aspekty polucheniia i isslodovaniia kompleksov kation metalla-fosfolipid.