Plasma lipid and lipoprotein profiles in pre- and post-menopausal middle-aged runners.
Plasma lipid and lipoprotein profiles were compared in middle-aged trained and untrained women before and after menopause. Subjects were assigned to one of four groups: (1) pre-menopausal trained (Pre-T: n = 17, aged 42 +/- 5 years, body fat 19 +/- 5%, training distance 53 +/- 20 km week-1, VO2max 49 +/- 4 ml kg-1 min-1, mean +/- SD); (2) pre-menopausal untrained (Pre-UT: n = 26, 42 +/- 5 years, 24 +/- 7%, 34 +/- 6 ml kg-1 min-1); (3) post-menopausal trained (Post-T: n = 16, 54 +/- 3 years, 20 +/- 4%, 43 +/- 19 km week-1, 41 +/- 5 ml kg-1 min-1); and (4) post-menopausal untrained (Post-UT: n = 15, 55 +/- 3 years, 25 +/- 6%, 31 +/- 3 ml kg-1 min-1). There were no significant differences in total cholesterol (range 173-194 mg dl-1), triglyceride (56-72 mg dl-1), and HDL-cholesterol (HDLC: 76-85 mg dl-1) among the four groups. LDL-cholesterol (LDLC) in the post-menopausal women (Post-T: 96 +/- 32 mg dl-1; Post-UT: 104 +/- 23 mg dl-1) tended to be higher than in the premenopausal women (Pre-T: 86 +/- 25 mg dl-1, Pre-UT: 81 +/- 23 mg dl-1).(ABSTRACT TRUNCATED AT 250 WORDS)
Higuchi
M
M
Division of Health Promotion, National Institute of Health and Nutrition, Tokyo, Japan.
Iwaoka
K
K
Ishii
K
K
Matsuo
S
S
Kobayashi
S
S
Tamai
T
T
Takai
H
H
Nakai
T
T
D000328:Adult; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*; D008593:Menopause / Q000097:blood* / Q000502:physiology; D008875:Middle Aged; D010743:Phospholipids / Q000097:blood; D012420:Running; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D008074:Lipoproteins; D010743:Phospholipids; D014280:Triglycerides; D002784:Cholesterol