Trisomy 5 and loss of the Y chromosome as the sole cytogenetic anomalies in a cavernous hemangioma/angiosarcoma.
Cytogenetic analysis of a cavernous hemangioma with transition to angiosarcoma revealed the mosaic karyotype 47,XY,+5/46,X,-Y,+5/45,X,-Y/46,XY. No cytogenetically analyzed hemangiomas or angiosarcomas have been reported before.
Mandahl
N
N
Department of Clinical Genetics, Lund University Hospital, Sweden.
Jin
Y S
YS
Heim
S
S
Willén
H
H
Wennerberg
J
J
Biörklund
A
A
Mitelman
F
F
D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D002872:Chromosome Deletion; D002895:Chromosomes, Human, Pair 5; D006392:Hemangioma, Cavernous / Q000235:genetics* / Q000473:pathology; D006394:Hemangiosarcoma / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007621:Karyotyping; D008297:Male; D014314:Trisomy; D014998:Y Chromosome