Autoantibodies to the thyrotrophin receptor mimic thyrotrophin in stimulating both thyroglobulin and thyroid peroxidase mRNA transcription in human thyroid cells.
Collison
K S
KS
Department of Medicine, King's College Hospital School of Medicine, Denmark Hill, London, U.K.
Banga
J P
JP
Barnett
P S
PS
Huang
G C
GC
McGregor
A M
AM
D001323:Autoantibodies / Q000378:metabolism*; D002478:Cells, Cultured; D006111:Graves Disease / Q000276:immunology / Q000378:metabolism; D006801:Humans; D007453:Iodide Peroxidase / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D011989:Receptors, Thyrotropin / Q000276:immunology*; D013954:Thyroglobulin / Q000235:genetics; D013961:Thyroid Gland / Q000187:drug effects / Q000378:metabolism*; D013972:Thyrotropin / Q000494:pharmacology; D014158:Transcription, Genetic / Q000187:drug effects
D001323:Autoantibodies; D012333:RNA, Messenger; D011989:Receptors, Thyrotropin; D013972:Thyrotropin; D013954:Thyroglobulin; D007453:Iodide Peroxidase