title: [Studies on the production of epidermal cytokines after UVB irradiation in patients with epidermodysplasia verruciformis].
abstract: The production of interleukin-1 (IL-1) and interleukin-1 inhibitor by keratinocytes isolated from the skin of epidermodysplasia verruciformis patients was studied. Keratinocytes from uninvolved skin of patients with most pronounced neoplastic lesions produced large amounts of an IL-1 inhibitor (20-40 kD). Keratinocytes from preneoplastic lesions showed no significant differences compared to cells from healthy donors but their production of IL-1 after UVB irradiation was increased.
authors.affiliation: Kliniki Dermatologicznej AM w Warszawie.
authors.forename: S
authors.initials: S
authors.lastname: Majewski
authors.forename: J
authors.initials: J
authors.lastname: Malejczyk
authors.forename: A
authors.initials: A
authors.lastname: Urbanski
authors.forename: T
authors.initials: T
authors.lastname: Schwarz
authors.forename: M
authors.initials: M
authors.lastname: Malejczyk
authors.forename: J
authors.initials: J
authors.lastname: Misiewicz
authors.forename: L
authors.initials: L
authors.lastname: Rudnicka
authors.forename: J
authors.initials: J
authors.lastname: Szymańczyk
authors.forename: T A
authors.initials: TA
authors.lastname: Luger
authors.forename: S
authors.initials: S
authors.lastname: Jabłońska
mesh_terms: D000328:Adult; D004819:Epidermodysplasia Verruciformis / Q000378:metabolism* / Q000532:radiotherapy; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D007375:Interleukin-1 / Q000096:biosynthesis*; D015603:Keratinocytes / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions / Q000378:metabolism; D012878:Skin Neoplasms / Q000378:metabolism*; D014467:Ultraviolet Therapy
chemical_list: D007375:Interleukin-1
vernacular_title: Badania nad produkcja cytokin naskórkowych pod wpływem UVB u chorych z epidermodysplasia verruciformis.