Synthesis of some monodeoxy- and dideoxy-hexitols, and derivatives thereof, from D-glucono-1,5-lactone.
Syntheses of 2-deoxy-D-arabino-hexitol (1), D-rhamnitol (2), 1,2-dideoxy-D-arabino-hexitol (3), 2,3-dideoxy-D-erythro-hexitol (4), and some derivatives thereof are described. These compounds were obtained by reductive sequences on various compounds formed from methyl 3,4:5,6-di-O-isopropylidene-D-gluconate (9).
Regeling
H
H
Department of Organic Chemistry, University, Toernooiveld, Nijmegen, The Netherlands.
Chittenden
G J
GJ
D003837:Deoxy Sugars / Q000138:chemical synthesis* / Q000737:chemistry; D005942:Gluconates; D007783:Lactones; D015394:Molecular Structure; D013402:Sugar Alcohols / Q000138:chemical synthesis* / Q000737:chemistry
D003837:Deoxy Sugars; D005942:Gluconates; D007783:Lactones; D013402:Sugar Alcohols; C010730:beta-glucono-1,5-lactone