title: Ga-labeling of immunoglobulin G with high specific radioactivity.
abstract: To obtain radiogallium labeled immunoglobulin G with a high specific radioactivity for in vitro use, a 67Ga source was purified by extraction from 67Ga-gallium citrate with butyl acetate, and a 67Ga-labeling solution was produced. This solution was then used to label a deferoxamine-immunoglobulin G conjugate. Both a very high specific radioactivity (872 +/- 56 MBq/mg) and a high labeling efficiency (94.0%) were achieved.
authors.affiliation: Department of Health Chemistry, Kansai Medical University, Osaka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Furukawa
authors.forename: Y
authors.initials: Y
authors.lastname: Fujibayashi
authors.forename: M
authors.initials: M
authors.lastname: Fukunaga
authors.forename: A
authors.initials: A
authors.lastname: Yokoyama
mesh_terms: D005710:Gallium Radioisotopes; D007074:Immunoglobulin G; D007553:Isotope Labeling; D011863:Radioimmunoassay
chemical_list: D005710:Gallium Radioisotopes; D007074:Immunoglobulin G