title: Infectious crystalline keratopathy associated with topical anesthetic abuse.
abstract: Two patients with infectious crystalline keratopathy associated with topical anesthetic abuse are described. No previously reported predisposing factors existed, including topical corticosteroid use during active Herpes simplex or Acanthamoeba keratitis, or following penetrating keratoplasty. Cultures from corneal biopsies of both patients grew Streptococcus viridans. Both infections resulted in corneal scarring with vascularization. Ultimately, corneal transplantation was performed in one case.
authors.affiliation: Division of Ophthalmology, University Hospitals of Cleveland, Case Western Reserve University, Ohio.
authors.forename: J C
authors.initials: JC
authors.lastname: Kintner
authors.forename: H E
authors.initials: HE
authors.lastname: Grossniklaus
authors.forename: J H
authors.initials: JH
authors.lastname: Lass
authors.forename: G
authors.initials: G
authors.lastname: Jacobs
mesh_terms: D000328:Adult; D000779:Anesthetics, Local / Q000009:adverse effects*; D001706:Biopsy; D003316:Corneal Diseases / Q000209:etiology* / Q000473:pathology; D015818:Eye Infections, Bacterial / Q000209:etiology*; D005260:Female; D006801:Humans; D015948:Keratoplasty, Penetrating; D012651:Self Medication / Q000009:adverse effects*; D013290:Streptococcal Infections / Q000209:etiology*; D013291:Streptococcus / Q000302:isolation & purification
chemical_list: D000779:Anesthetics, Local