title: Genetic polymorphism of factor B of the complement system (Bf) in the Slovak population.
abstract: The distribution of factor B (Bf) phenotypes and gene frequencies were investigated in 280 genetically unrelated persons of the Slovak population. Thin-layer agarose gel high-voltage electrophoresis and subsequent immunofixation were used. A low frequency of the "rare" allele BfFl was observed (BfFl = 0.0017). The frequencies of common Bf alleles BfS and BfF (BfS = 0.816, BfF = 0.1625) and a "rare" allele BfSO.7 (BfSO.7 = 0.0178) were inside the corresponding ranges of BfS, BfF and BfSO.7 found in European Caucasoids. No other variants were observed.
authors.affiliation: Department of Microbiology and Immunology, Faculty of Medicine, Comenius University, Bratislava.
authors.forename: D
authors.initials: D
authors.lastname: Staneková
authors.forename: Z
authors.initials: Z
authors.lastname: Starsia
authors.forename: M
authors.initials: M
authors.lastname: Niks
mesh_terms: D000483:Alleles; D011415:Complement Factor B / Q000235:genetics*; D003604:Czechoslovakia; D004587:Electrophoresis, Agar Gel; D005787:Gene Frequency / Q000235:genetics; D006801:Humans; D010641:Phenotype; D011110:Polymorphism, Genetic
chemical_list: D011415:Complement Factor B