title: [Hyperkeratosis lenticularis perstans. A clinical case and review of the literature].
abstract: A case of a woman of 55-years-old with verrucous lesions localized on the dorsa of her feet and hands is reported. The light microecopy reveals marked hyperkeratosis with some degree of parakeratosis, epidermal atrophy and light lympho-histiocytic infiltrate in the papillary dermis. A diagnosis of hyperkeratosis lenticularis perstans is made on the basis of the physical examination and histologic findings. A brief review of the literature on the genetic, ultrastructural characteristics and pathogenesis of the disease is made.
authors.affiliation: Divisione di Dermatologia, E.O. Ospedali Galliera, Genova.
authors.forename: L
authors.initials: L
authors.lastname: Massone
authors.forename: A
authors.initials: A
authors.lastname: Pestarino
authors.forename: C
authors.initials: C
authors.lastname: Gambini
authors.forename: V
authors.initials: V
authors.lastname: Isola
mesh_terms: D005260:Female; D005533:Foot Dermatoses / Q000473:pathology*; D006229:Hand Dermatoses / Q000473:pathology*; D006801:Humans; D007642:Keratosis / Q000473:pathology*; D008875:Middle Aged
vernacular_title: Hyperkeratosis lenticularis perstans. Caso clinico e review della letteratura.