title: [Plasma levels of various gastrointestinal polypeptides in patients with cholelithiasis and different degree of functional disorders of the major duodenal papilla].
abstract: Findings of dynamic cholangiomanometry with the analysis of the tension curves are overviewed. This technique helped reveal different functional ailments of the bile papilla in major variants of the cholelithiasis course (acute obstructive++ cholecystitis, recurrent pancreatitis, and choledocholythiasis with obstructive jaundice). Parallel radioimmunoassay-based studies of a series of gastrointestinal polypeptides (insulin, glucagon, gastrin, vasoactive peptide, bombesin , and somatostatin) were conducted to determine the importance of these polypeptides in the pathogenesis of cholelithiasis complications. The levels of certain polypeptides were found to be related to the clinical manifestations of the disease. The complex assessment of the bile papilla function and gastrointestinal polypeptide concentrations offers a possibility for elaborating the pathogenetically relevant methods of therapy for this group of diseases.
authors.forename: A V
authors.initials: AV
authors.lastname: Pugachev
authors.forename: V A
authors.initials: VA
authors.lastname: Sandrikov
authors.forename: E P
authors.initials: EP
authors.lastname: Gitel'
authors.forename: P S
authors.initials: PS
authors.lastname: Gordeev
authors.forename: A V
authors.initials: AV
authors.lastname: Mukha
authors.forename: E M
authors.initials: EM
authors.lastname: Maĭorova
authors.forename: A R
authors.initials: AR
authors.lastname: Gambarian
authors.forename: Z U
authors.initials: ZU
authors.lastname: Rodzhiashvili
mesh_terms: D000328:Adult; D000368:Aged; D014670:Ampulla of Vater; D001651:Cholestasis, Extrahepatic / Q000097:blood*; D005260:Female; D042882:Gallstones / Q000097:blood*; D005768:Gastrointestinal Hormones / Q000097:blood*; D006801:Humans; D008875:Middle Aged; D010455:Peptides / Q000097:blood*; D012720:Severity of Illness Index
chemical_list: D005768:Gastrointestinal Hormones; D010455:Peptides
vernacular_title: Soderzhanie riada gastrointestinal'nykh polipeptidov v plazme krovi u bol'nykh zhelchekamennoĭ bolezn'iu s razlichnoĭ stepen'iu narusheniia funktsii bol'shogo sosochka dvenadtsatiperstno'i kishki.