title: Sensitization to povidone-iodine.
abstract: Eight patients are described with adverse skin reactions to povidone-iodine-containing preparations (Betadine). Patch test reactions were positive to povidone-iodine 5 or 10 per cent in petrolatum or to Betadine Solution, Ointment, or Scrub. In five of eight patients, also tested with potassium iodide in concentrations ranging from 5 to 20 per cent in petrolatum, the reactions were negative. Open tests with iodine tincture performed in three patients were completely negative. Allergy to povidone-iodine seems not to be based on sensitization to iodine.
authors.affiliation: Department of Occupational Dermatology, Free University Academic Hospital, Amsterdam, The Netherlands.
authors.forename: W G
authors.initials: WG
authors.lastname: van Ketel
authors.forename: W H
authors.initials: WH
authors.lastname: van den Berg
mesh_terms: D003877:Dermatitis, Contact / Q000209:etiology*; D004485:Eczema / Q000139:chemically induced*; D006801:Humans; D010328:Patch Tests / Q000379:methods; D011205:Povidone; D011206:Povidone-Iodine / Q000009:adverse effects*; D013997:Time Factors
chemical_list: D011206:Povidone-Iodine; D011205:Povidone