title: [Antithyroid antibody dynamics in patients with Hashimoto's goiter receiving conservative treatment and after surgical interventions].
abstract: The content of antithyroid antibodies (AtAb) in the blood of patients with Hashimoto's goiter was studied over time, namely during the treatment with thyroid drugs and after surgical interventions of different scope. The patients' groups with diverse changes in the AtAb titers during the conservative treatment were revealed. The analogous types of the time-course of changes in antibodies to thyroglobulins (AbTg) were discovered after a surgical intervention irrespective of the operation scope whereas the persistence of antibodies to microsomal antigen (AbMa) after the operation depended on the mass of the remaining thyroid tissue. A correlation was found between the high titers of AbTg (rather than AbMa) and the elevated content of thyrotropic hormone in untreated patients with Hashimoto's goiter and after large-scope surgical interventions.
authors.forename: T A
authors.initials: TA
authors.lastname: Okeanova
authors.forename: S L
authors.initials: SL
authors.lastname: Vnotchenko
authors.forename: G I
authors.initials: GI
authors.lastname: Fedoseeva
authors.forename: E N
authors.initials: EN
authors.lastname: Bazarova
authors.forename: I V
authors.initials: IV
authors.lastname: Kriukova
authors.forename: E V
authors.initials: EV
authors.lastname: Konnova
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000906:Antibodies / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D013954:Thyroglobulin / Q000276:immunology; D013961:Thyroid Gland / Q000276:immunology*; D013965:Thyroidectomy / Q000379:methods; D013967:Thyroiditis, Autoimmune / Q000097:blood / Q000276:immunology* / Q000628:therapy; D013972:Thyrotropin / Q000097:blood
chemical_list: D000906:Antibodies; D013972:Thyrotropin; D013954:Thyroglobulin
vernacular_title: Dinamika antitireoidnykh antitel u bol'nykh zobom Khashimoto na fone konservativnogo lecheniia i posle operativnykh vmeshatel'stv.