[Effect of biliary obstruction and cholangitis on serum SPan-1 level].
We investigated the effect of biliary obstruction and cholangitis on serum SPan-1 level in 14 patients (5 patients with pancreatic cancer and 9 patients with biliary tract cancer) who were performed PTCD for biliary obstruction. 1 out of 5 cases with pancreatic cancer and 8 out of 9 cases with biliary tract cancer showed a decrease of SPan-1 level with improvement of jaundice. It suggested that the effect of biliary obstruction and cholangitis on serum SPan-1 level was much more in biliary tract cancer than in pancreatic cancer. There was no significant difference in changes of between serum SPan-1 level and serum CA 19-9 level after PTCD. We conclude that the effect of biliary obstruction and cholangitis on serum SPan-1 level is almost same on serum CA 19-9 level.
Matsumoto
S
S
Department of Radiology, National Fukuoka Central Hospital.
Muranaka
T
T
Hanada
K
K
Matsuura
Y
Y
Oshiumi
Y
Y
D000951:Antigens, Neoplasm / Q000032:analysis*; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis; D001661:Biliary Tract Neoplasms / Q000097:blood*; D014408:Biomarkers, Tumor / Q000032:analysis*; D002761:Cholangitis / Q000097:blood*; D002779:Cholestasis / Q000097:blood* / Q000601:surgery; D006801:Humans; D010190:Pancreatic Neoplasms / Q000097:blood*
D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor; C059729:pancreatic associated antigen, SPan-1