Human scalp hair as evidence of individual dosage history of haloperidol: longer-term follow-up study.
The patients reported in our previous paper were followed further, by analyzing hair samples collected monthly for 4 or 5 months, while growing hair continues to reflect the individual dosage history of haloperidol. In patients in whom the drug had been discontinued, the portion of hair that reflected the change of dose continued to move upward. In hair of patients in whom the dosage was decreased by one-half, the portion of change was also shown to move upward. These results indicate the potential usefulness of hair for assessing the individual past dosage history of haloperidol.
Uematsu
T
T
Department of Pharmacology, Hamamatsu University School of Medicine, Japan.
Sato
R
R
D000293:Adolescent; D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006197:Hair / Q000737:chemistry*; D006220:Haloperidol / Q000008:administration & dosage / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D012535:Scalp / Q000737:chemistry; D013997:Time Factors
D006220:Haloperidol