[Use of enzyme test in chemotherapy of patients with cancer of the breast].
The activity of thymidine kinase, thymidine phosphorylase, adenosine deaminase, AMP 5'-nucleotidase was assessed in the serum of healthy females, patients with mastopathia cystica and those with stage IIIB breast cancer. The females age ranged from 23 to 70 years. The activity of the enzymes had significant differences in cancer patients. Minimal thymidine phosphorylase activity was found to suggest fibrous cancer. Changes in the enzymes levels in cancer patients on combined treatment may serve a biochemical test indicating the efficacy of the chemotherapy conducted.
Borzenko
B G
BG
D015720:5'-Nucleotidase / Q000097:blood; D000243:Adenosine Deaminase / Q000097:blood; D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000188:drug therapy* / Q000601:surgery; D004796:Clinical Enzyme Tests; D003937:Diagnosis, Differential; D005260:Female; D005348:Fibrocystic Breast Disease / Q000175:diagnosis; D006801:Humans; D008875:Middle Aged; D013937:Thymidine Kinase / Q000097:blood; D013939:Thymidine Phosphorylase / Q000097:blood
D013939:Thymidine Phosphorylase; D013937:Thymidine Kinase; D015720:5'-Nucleotidase; D000243:Adenosine Deaminase
Ispol'zovanie fermentativnogo testa pri khimioterapii bol'nykh rakom molochnoĭ zhelezy.