[An analysis of the expression of the mutant angora-Y gene in the mouse].
We studied the rate and duration of the growth of G1 and G3 hairs in mice homozygous for angora-Y mutant gene (goY). The follicular diameter of G3 hairs and the growth rate of G1 and G3 hairs in goY/goY mice do not differ from normal. However, the duration of growth period of all four studied types of hairs in goY/goY mice is longer than in the normal phenotype. Growth of the guard hairs G1 and G3 in mutants continues longer than in the normal phenotype by 7 and 3 days, respectively. For other hair types G1 and G3 (awl, auchene, zigzag) the duration of the growth period is approximately 3 days longer than in the control. As a result in goY/goY mice guard hairs G1 and G3 which have completed growth are 2 and 1.5 times longer than in +/+ mice. Other types of G1 hairs in mutants are longer by 50% and G3 hairs by 30% than in the wild type.
Koniukhov
B V
BV
Berdaliev
A S
AS
D000375:Aging / Q000502:physiology; D000818:Animals; D002965:Classification; D005260:Female; D005786:Gene Expression Regulation / Q000502:physiology*; D005808:Genes, Recessive / Q000502:physiology*; D005838:Genotype; D006197:Hair / Q000254:growth & development*; D006720:Homozygote; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008817:Mice, Mutant Strains; D009154:Mutation / Q000502:physiology*
Analiz ékspressii mutantnogo gena angora-Y u myshi.