Death following suspected alprazolam withdrawal seizures: a case report.
This is a case report of severe psychosis and seizures following abrupt discontinuation of alprazolam and then the recurrence of seizures at the end of a gradual tapering schedule. The last of these seizures appeared to be a contributing factor in the patient's death. To the authors' knowledge, this is the first published report of a fatality associated with alprazolam withdrawal.
Haque
W
W
Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, Galveston 77550.
Watson
D J
DJ
Bryant
S G
SG
D000525:Alprazolam / Q000009:adverse effects*; D001145:Arrhythmias, Cardiac / Q000150:complications / Q000209:etiology; D003645:Death, Sudden / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011605:Psychoses, Substance-Induced / Q000209:etiology; D012008:Recurrence; D012640:Seizures / Q000139:chemically induced* / Q000150:complications; D013375:Substance Withdrawal Syndrome
D000525:Alprazolam