An open study of the efficacy and safety of single dose fosfomycin trometamol in treatment of hospitalised patients with urinary tract infection (pilot study).
Single dose fosfomycin trometamol (3 g) was used to treat 20 hospitalised patients with UTI. Tolerance was good or excellent in 19/20 patients; a satisfactory bacteriological outcome was recorded in 11/17 of patients with sensitive organisms and a satisfactory clinical outcome was noted in 12/16 symptomatic individuals.
MacGowan
A P
AP
Department of Medical Microbiology, Southmead Hospital, Bristol, United Kingdom.
Bailey
R A
RA
Egner
W
W
Picken
D M
DM
Reeves
D S
DS
D000284:Administration, Oral; D000368:Aged; D000369:Aged, 80 and over; D004361:Drug Tolerance; D004926:Escherichia coli / Q000187:drug effects; D005260:Female; D005578:Fosfomycin / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D012074:Remission Induction; D013997:Time Factors; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology
D005578:Fosfomycin