Carriage and antibiotic susceptibility of Haemophilus influenzae type b and non b in Danish day-care attendees.
A study of carriage of Haemophilus influenzae type b (Hib) and non b in Danish day-care facilities, employing a highly selective medium supplemented with three antibiotics and direct detection of the type b capsular antigen by latex-agglutination and coagglutination, was carried out. Of 329 children, 217 (66%) were found to be carriers of Haemophilus influenzae. Among 64 children from day-care centers in which a case of invasive Hib infection had occurred, four carriers of type b were found, whereas no type b carriers were identified among 265 children from unexposed day-care centers (p less than 0.003). Of 217 isolated strains, seven (3.2%) were found to have lowered susceptibility to ampicillin, two (0.9%) to chloramphenicol, two (0.9%) to cefuroxim, and one (0.5%) to cefotaxim.
Kristensen
K
K
Streptococcus Department, Statens Seruminstitut, Copenhagen, Denmark.
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002353:Carrier State; D002648:Child; D002675:Child, Preschool; D003631:Day Care, Medical; D003718:Denmark; D006192:Haemophilus Infections / Q000635:transmission*; D006193:Haemophilus influenzae / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D008826:Microbial Sensitivity Tests
D000900:Anti-Bacterial Agents