[Lethal midline granuloma as a result of months-long immunosuppressive therapy. A case report].
A case of lethal midline granuloma is reported, which resulted from immunosuppressive therapy with corticoids over months because of pulmonary fibrosis. An autoimmune disease according to a cell mediated immune reaction (type IV--classification of Coombs and Gell) is discussed. Wegener's granulomatosis and a T-cell lymphoma were excluded. Continuation of this lymphoproliferative disease would eventually have resulted in a T-cell lymphoma.
Suttner
H J
HJ
Universitäts-Hals-Nasen-Ohren-Klinik Heidelberg.
Enzmann
H
H
D002908:Chronic Disease; D003937:Diagnosis, Differential; D006103:Granuloma, Lethal Midline / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011658:Pulmonary Fibrosis / Q000150:complications / Q000473:pathology / Q000628:therapy; D012852:Sinusitis / Q000175:diagnosis; D013997:Time Factors
Letales Mittelliniengranulom infolge monatelanger immunsuppressiver Therapie.