[A study on the serological effects of newborn babies using China made 50 micrograms hepatitis B vaccine].
The blood source Hepatitis B vaccine produced by Beijing Institute of Biological Products was given to New born babies. The procedure and doses are as follows: first dose 30 micrograms was given within 24 hours after birth; second dose 10 micrograms was given one month after birth and the third dose 10 micrograms was given 6 months after birth. The sera samples were collected during 1-6 months after 3 times of inoculation. And tested HBsAg, anti-HBs and anti-HBc by using Solid-phase Radioimmunoassay (SPRIA). In total, 288 sera samples were tested. All samples were negative in HBsAg; Positive rate of anti-HBs was 96.18%, geometric titer was 1105.14 mIU/m. The results showed that the China made 50 micrograms Hepatitis B vaccine has a good serological effect on newborn babies.
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Sanitary and Anti-Epidemic Station of Hei Long Jiang Province, Harbin.
D000914:Antibodies, Viral / Q000032:analysis; D005260:Female; D006509:Hepatitis B / Q000517:prevention & control*; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011863:Radioimmunoassay; D014761:Viral Hepatitis Vaccines
D000914:Antibodies, Viral; D006514:Hepatitis B Surface Antigens; D014761:Viral Hepatitis Vaccines