Bovine viral diarrhea virus-induced cerebellar disease in a calf.
Bovine viral diarrhea virus (BVDV) was isolated from buffy coat cells of a 10-day-old calf with signs of cerebellar disease--ataxia, hypermetria, and intention head tremor. The tentative diagnosis was BVDV-induced cerebellar hypoplasia. At necropsy, gross lesions were not identified. Histologic findings suggested BVDV-induced diffuse hypomyelination throughout the CNS, as reported in the United Kingdom and The Netherlands.
Riond
J L
JL
Department of Food Animal and Equine Medicine, College of Veterinary Medicine, North Carolina State University, Raleigh 27606.
Cullen
J M
JM
Godfrey
V L
VL
Hunt
E L
EL
Anderson
K L
KL
D000818:Animals; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000473:pathology*; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology*; D002526:Cerebellar Diseases / Q000473:pathology / Q000662:veterinary*; D002531:Cerebellum / Q000473:pathology; D005260:Female; D009186:Myelin Sheath / Q000473:pathology