title: Chromosome abnormalities in multiple meningiomas of a child.
abstract: We report the cytogenetic findings in two meningiomas from a child presenting with multiple meningiomas. In contrast to the chromosomal profile of adult meningiomas, both tumors studied revealed excess of chromosomes in addition to monosomy 22. This difference is remarkable considering several reports indicating that childhood meningiomas behave differently and have a worse prognosis than those in adults.
authors.affiliation: Institut für Humangenetik und Anthropologie der Universität, Freiburg, Federal Republic of Germany.
authors.forename: B
authors.initials: B
authors.lastname: Wullich
authors.forename: L
authors.initials: L
authors.lastname: Mayfrank
authors.forename: K
authors.initials: K
authors.lastname: Schwechheimer
authors.forename: J
authors.initials: J
authors.lastname: Finke
authors.forename: W
authors.initials: W
authors.lastname: Schempp
mesh_terms: D000782:Aneuploidy; D001932:Brain Neoplasms / Q000235:genetics*; D002648:Child; D002869:Chromosome Aberrations; D002892:Chromosomes, Human, Pair 22; D005260:Female; D006801:Humans; D007621:Karyotyping; D008579:Meningioma / Q000235:genetics*; D009006:Monosomy; D009378:Neoplasms, Multiple Primary / Q000235:genetics*