title: [Results and prospects of development of neuropharmacology in the department of pharmacology of the Acad. S. V. Anichkov Research Institute of Experimental Medicine, USSR Academy of Medical Sciences].
abstract: Basic strategic and tactical principles of neuropharmacological studies are outlined, whose aim is to find and explore new synthetic neuro-blocking agents and substances simulating the structure of natural metabolites. The basic research has resulted in the development of new highly effective drugs and experimentally substantiated recommendations for their clinical application. The conceptions of the action mechanism of adrenergic and cholinergic agents, stimulants of tissue energy exchange, which have been formulated in the department, suggested new approaches to the pharmacological treatment of diseases of the central and peripheral nervous systems and neurogenic diseases of the gastrointestinal and cardiovascular systems.
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Borodkin
authors.forename: I S
authors.initials: IS
authors.lastname: Zavodskaia
authors.forename: N A
authors.initials: NA
authors.lastname: Losev
authors.forename: E V
authors.initials: EV
authors.lastname: Moreva
authors.forename: N S
authors.initials: NS
authors.lastname: Sapronov
mesh_terms: D000818:Animals; D006801:Humans; D009422:Nervous System Diseases / Q000188:drug therapy; D009480:Neuropharmacology / Q000639:trends*; D010277:Parasympathomimetics / Q000627:therapeutic use; D051381:Rats; D012106:Research; D013566:Sympathomimetics / Q000627:therapeutic use; D014586:USSR
chemical_list: D010277:Parasympathomimetics; D013566:Sympathomimetics
vernacular_title: Itogi i perspektivy razvitiia neĭrofarmakologii v otdele farmakologii im. akad. AMN SSSR S. B. Anichkova NII éksperimental'noĭ meditsiny AMN SSSR.