Changes in the synaptic region of auditory hair cells during noise-induced temporary threshold shift.
During noise-induced temporary threshold shift cytoplasmic vacuoles increase in the synaptic region of auditory hair cells. This structural change in the presynaptic region suggests that afferent synapses between hair cells and auditory nerve fibers fail during the period of threshold elevation, and that synaptic fatigue may play a major role.
Mulroy
M J
MJ
Department of Anatomy, Medical College of Georgia, Augusta 30912.
Fromm
R F
RF
Curtis
S
S
D000818:Animals; D003055:Cochlear Microphonic Potentials; D006198:Hair Cells, Auditory / Q000502:physiology* / Q000648:ultrastructure; D008116:Lizards; D008854:Microscopy, Electron; D009622:Noise; D012684:Sensory Thresholds; D013569:Synapses / Q000502:physiology*; D013997:Time Factors; D014617:Vacuoles / Q000648:ultrastructure; D000159:Vestibulocochlear Nerve / Q000502:physiology