title: A unique fucoganglioside with blood group B determinant in rat spleen.
abstract: A unique fucoganglioside was isolated from rat spleen and characterized by compositional analysis, methylation analysis, exoglycosidase treatment, negative ion fast atom bombardment (FAB) mass spectrometry, and proton NMR spectrometry. The ganglioside was identified as alpha Gal,Fuc-GM1(NeuGc), which has the blood group B determinant at the nonreducing termini, as shown below: (formula; see text) This is the first report describing the occurrence in nature of alpha Gal,Fuc-GM1 containing N-glycolylneuraminic acid.
authors.affiliation: National Institute for Environmental Studies, Ibaraki.
authors.forename: K
authors.initials: K
authors.lastname: Nohara
authors.forename: M
authors.initials: M
authors.lastname: Suzuki
authors.forename: F
authors.initials: F
authors.lastname: Inagaki
authors.forename: H
authors.initials: H
authors.lastname: Ito
authors.forename: K
authors.initials: K
authors.lastname: Kaya
mesh_terms: D000017:ABO Blood-Group System; D000818:Animals; D002240:Carbohydrate Sequence; D005227:Fatty Acids / Q000032:analysis; D005260:Female; D005732:Gangliosides / Q000302:isolation & purification*; D006868:Hydrolysis; D008297:Male; D008745:Methylation; D008969:Molecular Sequence Data; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000737:chemistry*
chemical_list: D000017:ABO Blood-Group System; D005227:Fatty Acids; D005732:Gangliosides; C031153:fucogangliosides