title: Adrenoleukodystrophy associated with cerebral arteriovenous malformation.
abstract: Adrenoleukodystrophy (ALD) is now considered to be an X-linked recessive peroxisomal disorder. We report the case of a patient with ALD associated with a left parietal arteriovenous malformation (AVM) who deteriorated progressively six months after recovery from a hemorrhage of the AVM. Serial CT scans and MR imagings showed progressive demyelination spreading from the affected area. This case suggests that local brain damage due to AVM hemorrhage may accelerate the progress of demyelination.
authors.affiliation: Department of Neuropediatrics, Metropolitan Medical Center for the Severely Handicapped, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kubota
authors.forename: E
authors.initials: E
authors.lastname: Kurihara
authors.forename: M
authors.initials: M
authors.lastname: Yonezawa
authors.forename: Y
authors.initials: Y
authors.lastname: Mizuno
authors.forename: K
authors.initials: K
authors.lastname: Tamagawa
authors.forename: K
authors.initials: K
authors.lastname: Komiya
authors.forename: Y
authors.initials: Y
authors.lastname: Suzuki
mesh_terms: D000326:Adrenoleukodystrophy / Q000150:complications*; D002543:Cerebral Hemorrhage / Q000150:complications; D002648:Child; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000150:complications*; D008297:Male