title: [Acicular ichthyosis (the Curth-Macklin type)].
abstract: It is suggested that the double-nucleus phenomenon in the epidermis in type Curth-Macklin [correction of Kurt-McLean] acicular ichthyosis is due to cytokinesis-controlling gene mutation. Other hereditary dermatoses associated with needle-like hyperkeratosis appear to be a heterogenic group not necessarily involving the formation of double-nuclear cells. The essence of double-nucleus phenomenon and morphogenesis of acicular ichthyosis are disputable at present.
authors.forename: A A
authors.initials: AA
authors.lastname: Aĭvazian
mesh_terms: D002467:Cell Nucleus / Q000648:ultrastructure; D006801:Humans; D007057:Ichthyosis / Q000175:diagnosis* / Q000473:pathology; D007223:Infant; D008297:Male; D008854:Microscopy, Electron; D012867:Skin / Q000473:pathology; D013577:Syndrome
vernacular_title: Iglistyĭ ikhtioz (tip Kurta--Maklina).