Histopathological findings in the biopsied muscle of a juvenile type III glycogenosis.
We report a case of juvenile type III glycogenosis that was confirmed by histopathological and biochemical studies. The histopathological findings consisted of vacuoles, periodic acid-Schiff positive materials, type 2B fiber deficiency, mildly positive acid phosphatase reaction and intensely positive non-specific esterase reaction. It is suggested that the enzyme reactions may be related to membrane-bound sacs containing glycogen.
Hachisuka
K
K
Department of Rehabilitation Medicine, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Umezu
Y
Y
Nagayoshi
M
M
Hasegawa
E
E
Ohnishi
A
A
D000135:Acid Phosphatase / Q000378:metabolism; D000293:Adolescent; D000367:Age Factors; D004950:Esterases / Q000378:metabolism; D006004:Glycogen Debranching Enzyme System / Q000378:metabolism; D006010:Glycogen Storage Disease Type III / Q000201:enzymology / Q000473:pathology*; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009132:Muscles / Q000201:enzymology / Q000473:pathology* / Q000648:ultrastructure
D006004:Glycogen Debranching Enzyme System; D004950:Esterases; D000135:Acid Phosphatase