Reproductive immunology: relevance to infertility practice.
Both, men and women can develop antisperm antibodies as the response to numerous factors, however immune-mediated infertility is a relative condition, i.e. may reduce but not totally prevent fertility. Different techniques can detect antisperm antibodies and show how these antibodies may interfere with fertilization process. To overcome immune-mediated infertility, the immunosuppressive therapy and in vitro treatment of antibody-coated sperm cells including in vitro fertilization have been proposed.
Alexander
N J
NJ
Department of Obstetrics and Gynecology, Howard and Georgeanna Jones Institute for Reproductive Medicine, Eastern Virginia Medical School, Norfolk 23507.
D000906:Antibodies; D005260:Female; D006801:Humans; D007246:Infertility / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D008297:Male; D012098:Reproduction / Q000276:immunology*; D013094:Spermatozoa / Q000276:immunology
D000906:Antibodies