Human immunodeficiency virus transmission through artificial insemination.
Six human immunodeficiency virus type 1 (HIV-1) seropositive semen donors were identified during an antibody screening program initiated at an artificial insemination clinic in New York City in 1985. A total of 176 women underwent artificial insemination with fresh semen from these six donors between 1978 and mid-1985. Of these 176 women, 134 women were HIV-1 antibody tested and 1 was found to be seropositive; she denied all other AIDS-associated risk behavior and her husband was seronegative. The results of this investigation provide additional evidence that HIV-1 transmission can occur through artificial insemination with semen from an infected donor although the risk of HIV-1 transmission appears to be lower than that reported by other investigators. It is clear that HIV-1 screening of all potential semen donors should be routine practice whenever artificial insemination is performed.
Chiasson
M A
MA
AIDS Research Unit, New York City Department of Health, New York 10013.
Stoneburner
R L
RL
Joseph
S C
SC
D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology / Q000635:transmission*; D005260:Female; D006679:HIV Seropositivity; D015497:HIV-1; D006801:Humans; D007315:Insemination, Artificial; D007316:Insemination, Artificial, Heterologous; D008297:Male; D009519:New York City / Q000453:epidemiology