[The development of a complex Leptospira antigenic erythrocyte diagnostic agent].
Blood-sensitive activity of antigenic extracts obtained from leptospiras using the supersound and sodium dodecyl sulphate has been studied. Erythrocytic diagnostica, obtained on the basis of the mentioned sensitines, possess the genus and serogroup specificity, which expands their diagnostic spectrum. New diagnostica are shown to possess higher sensitivity as compared with the previously developed leptospirosis genus-specific erythrocytic diagnostica. The data are presented confirming the prospects of development of erythrocytic diagnostica based on antigens of leptospiras obtained by means of a supersound and sodium dodecyl sulphate. These preparations may be used in the diagnosis of human and animal leptospirosis.
Bernasovskaia
E P
EP
Mel'nitskaia
E V
EV
Kondratenko
V N
VN
D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D000918:Antibody Specificity / Q000276:immunology; D000942:Antigens, Bacterial / Q000302:isolation & purification; D003429:Cross Reactions / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology*; D006386:Hemagglutination Tests; D006801:Humans; D007919:Leptospira / Q000276:immunology*; D007922:Leptospirosis / Q000175:diagnosis* / Q000662:veterinary
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial
Razrabotka leptospiroznogo kompleksnogo antigennogo éritrotsitarnogo diagnostikuma.