Pregnancy in a homozygous familial hypercholesterolemic patient treated with long-term plasma exchange.
We describe the first pregnancy in a homozygous familial hypercholesterolemic woman who started plasma exchange therapy 3 years before she became pregnant. We especially studied the effects of plasma exchange on lipid profile, uteroplacental circulation, and pregnancy course.
Beigel
Y
Y
Lipid Unit, Beilinson Medical Center, Sackler School of Medicine, Tel Aviv University, Petah Tiqua, Israel.
Hod
M
M
Fuchs
J
J
Lurie
J
J
Friedman
S
S
Green
P
P
Merlob
P
P
Melamed
R
R
Ovadia
J
J
D002784:Cholesterol / Q000097:blood; D005260:Female; D005312:Fetal Blood; D006720:Homozygote; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000097:blood / Q000628:therapy*; D007231:Infant, Newborn; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D010920:Placenta / Q000098:blood supply; D010951:Plasma Exchange; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic; D012039:Regional Blood Flow; D013997:Time Factors; D014599:Uterus / Q000098:blood supply
D008077:Lipoproteins, LDL; D002784:Cholesterol