[Study of genetic markers in families of patients with tuberculosis].
The article deals with findings of the study of HLA-genotype influence on tuberculosis susceptibility in 26 families with tuberculosis patients. It was found that sensitivity to tuberculosis in the examined families is associated with HLA-DR2 antigen. Segregation analyses conducted in the families of patients with tuberculosis revealed a correlation between the sensitivity to tuberculosis and inheritance of certain HLA haplotypes from the affected parents to their children with tuberculosis.
Rakhimov
A Kh
AKh
Pospelov
L E
LE
D000328:Adult; D002648:Child; D004198:Disease Susceptibility; D005190:Family; D005260:Female; D005819:Genetic Markers; D005838:Genotype; D006680:HLA Antigens / Q000032:analysis; D015802:HLA-DR2 Antigen / Q000032:analysis; D006801:Humans; D008297:Male; D014376:Tuberculosis / Q000235:genetics*
D005819:Genetic Markers; D006680:HLA Antigens; D015802:HLA-DR2 Antigen
Izuchenie geneticheskikh markerov v sem'iakh bol'nykh tuberkulezom.