[Effects of auricular electrostimulation and naloxone on nociceptive sensitivity in rabbits].
Auriculo-acupuncture electrostimulation (AES) (15 H2) decreased the amplitude of somatosensory evoked potential (EP) in response to tooth pulp electrostimulation in 64% of acupuncture-sensitive unanesthetized rabbits and didn't induce the changes of EP in 36% of animals (acupuncture-resistant rabbits). The systemic naloxone (0.2 mg/kg) injection reversed the AES analgetic effect and induced the hyperalgesic one in acupuncture-sensitive rabbits but induced the analgetic effect in acupuncture-resistant animals. It has been suggested that the differences of individual characteristics of endogenous opioid system determined different naloxone action in acupuncture-sensitive and acupuncture-resistant rabbits.
Raevskaia
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OS
Grishanin
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GG
D000698:Analgesia; D000818:Animals; D004558:Electric Stimulation; D015671:Electroacupuncture; D005073:Evoked Potentials, Somatosensory; D008297:Male; D009270:Naloxone / Q000494:pharmacology*; D010146:Pain / Q000503:physiopathology; D010147:Pain Measurement; D011817:Rabbits
D009270:Naloxone
Vliianie aurikuliarnoĭ élektrostimuliatsii i naloksona na notsitseptivnuiu chuvstvitel'nost' u krolikov.