[Evaluation of large doses of vitamin E in the treatment of anemia in patients with chronic renal failure].
The studied group comprised 10 patients with chronic renal failure on a programme of extracorporeal haemodialyses continued since 4 to 52 months, in whom the haematocrit value obtained during monthly laboratory investigations was below 21%, and who required at least one blood transfusion in three months. Before the study, after 3 months of treatment with vitamin E 600 mg in 24 hours, and 3 months after the completion of this treatment the following parameters were analysed: haemoglobin level, erythrocyte count, volume of blood transfused in various periods of the treatment. A slight rise of haematocrit value, haemoglobin level and erythrocyte count was observed after vitamin E treatment, but this rise was not significant statistically. No effect of vitamin E was noted on the osmotic resistance of the erythrocytes and the amount of blood transfused in the observed time periods. No side effects of vitamin E were noted.
Bogdanowicz
G
G
Oddziału Nefrologicznego i Ośrodka Dializ Wojewódzkiego Szpitala Zespolonego w Opolu.
Kwieciński
R
R
D000328:Adult; D000740:Anemia / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D004906:Erythrocyte Count / Q000187:drug effects; D005260:Female; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000150:complications*; D008875:Middle Aged; D014810:Vitamin E / Q000008:administration & dosage*; D014811:Vitamin E Deficiency / Q000097:blood / Q000188:drug therapy* / Q000209:etiology
D006454:Hemoglobins; D014810:Vitamin E
Ocena duzych dawek wit. E w leczeniu niedokrwistości u chorych z przewlekła niewydolnościa nerek.