Glutathione peroxidase and selenium levels in the preterm infant.
Glutathione peroxidase (GPX) and selenium are important in the prevention of cellular oxidant damage. Whole-blood GPX and plasma selenium were measured at birth and sequentially afterwards in 75 preterm babies. GPX activity at birth was 2.74 +/- 0.08 (mean +/- SEM) U/ml. Mean GPX activity remained relatively unchanged for up to 70 days postnatal age. Plasma selenium at birth was 0.43 +/- 0.02 (mean +/- SEM) mumol/l), decreasing to low levels by 10 weeks postnatal age. Neither GPX activity nor plasma selenium was related to birth weight, gestational age or infant sex.
Tubman
T R
TR
Neonatal Intensive Care Unit, Royal Maternity Hospital, Belfast, UK.
Halliday
H L
HL
McMaster
D
D
D000367:Age Factors; D005260:Female; D005979:Glutathione Peroxidase / Q000097:blood* / Q000378:metabolism; D006801:Humans; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D007234:Infant, Premature / Q000097:blood*; D008297:Male; D009660:Northern Ireland; D012643:Selenium / Q000097:blood* / Q000378:metabolism; D012987:Soil
D012987:Soil; D005979:Glutathione Peroxidase; D012643:Selenium