Indications for keratoepithelioplasty.
Thirteen patients with ocular surface failure were treated by keratoepithelioplasty using allografts of corneal limbal epithelial cells from donor eyes. The ocular surface was stabilized with long-term healing of persistent epithelial defects in five of eight eyes followed up for 4 to 19 months. The procedure was performed on an additional 5 patients with superficial keratopathies. Three of those five procedures resulted in a stable and clear optical surface. These results suggest that epithelial transplantation may be a useful option in the care of chronic ocular surface failure unresponsive to conventional medical management.
Turgeon
P W
PW
Eye and Ear Institute, University of Pittsburgh, PA 15213.
Nauheim
R C
RC
Roat
M I
MI
Stopak
S S
SS
Thoft
R A
RA
D000328:Adult; D015783:Aniridia / Q000150:complications; D003315:Cornea / Q000601:surgery; D003316:Corneal Diseases / Q000209:etiology / Q000601:surgery*; D004848:Epithelium / Q000637:transplantation*; D005126:Eye Burns / Q000150:complications; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015948:Keratoplasty, Penetrating / Q000009:adverse effects; D008297:Male; D008722:Methods; D008875:Middle Aged; D011379:Prognosis; D013262:Stevens-Johnson Syndrome / Q000150:complications; D014792:Visual Acuity