Distribution of hypoxia-induced calcium accumulation in gerbil hippocampal slice.
Microfluorometry was used to examine distribution of hypoxia-induced intracellular free calcium accumulations in Mongolian gerbil hippocampal slice. Acute increase of intracellular free calcium was detected 80-170 s after the beginning of hypoxia. Large calcium accumulations were seen in the stratum radiatum, stratum lacunosum and stratum oriens of CA1 region and in the inner portions of the dentate gyrus molecular layer, and moderate accumulations were seen in the other laminae of CA1 region, other portions of dentate gyrus and the CA3 region.
Mitani
A
A
Department of Physiology, School of Medicine, Ehime University, Japan.
Kadoya
F
F
Kataoka
K
K
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D016257:Fura-2; D005849:Gerbillinae; D006624:Hippocampus / Q000378:metabolism*; D000860:Hypoxia; D066298:In Vitro Techniques; D007700:Kinetics; D008856:Microscopy, Fluorescence
D002118:Calcium; D016257:Fura-2