Evaluation and treatment of a male factor component to unexplained infertility.
The standard semen analysis frequently fails to identify subfertile males even when findings are normal and conversely often fails to identify fertile males with subnormal semen analyses. This has created the need to produce other tests of sperm physiology that will better distinguish a fertile from a subfertile specimen. Understanding more about the nature of the sperm defect should lead to the establishment of more specific and effective therapies. Until that time, it would still be reasonable to try some of the available empirical therapies even though they may work merely by a placebo mechanism.
Check
J H
JH
UMDNJ, Robert Wood Johnson Medical School, Camden.
Nowroozi
K
K
Lee
M
M
Adelson
H
H
Katsoff
D
D
D001205:Ascorbic Acid / Q000627:therapeutic use; D002996:Clomiphene / Q000627:therapeutic use; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007248:Infertility, Male / Q000209:etiology* / Q000628:therapy; D008297:Male; D012661:Semen / Q000166:cytology; D013084:Sperm-Ovum Interactions; D013090:Spermatocytes / Q000502:physiology*
D002996:Clomiphene; D001205:Ascorbic Acid