title: Serum concentrations of prilocaine following retrobulbar block.
abstract: Retrobulbar block for eye surgery is associated with adverse reactions. We performed retrobulbar block in 10 patients using prilocaine (Citanest) and found mean (SD) peak serum concentrations of 851 (165.6) ng ml-1 (range 540-1100 mg ml-1). Peak serum concentrations occurred 3-7 min after the end of administration of the block, and in all cases were less than those associated with toxicity.
authors.affiliation: Department of Ophthalmology, St Vincent's Hospital, Dublin.
authors.forename: M
authors.initials: M
authors.lastname: Goggin
authors.forename: K
authors.initials: K
authors.lastname: Crowley
authors.forename: K
authors.initials: K
authors.lastname: O'Malley
authors.forename: P
authors.initials: P
authors.lastname: Barry
authors.forename: G
authors.initials: G
authors.lastname: Kelly
authors.forename: J
authors.initials: J
authors.lastname: Blake
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction; D005123:Eye / Q000294:innervation*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009407:Nerve Block; D011318:Prilocaine / Q000008:administration & dosage / Q000097:blood*; D011625:Pterygium / Q000601:surgery; D013997:Time Factors
chemical_list: D011318:Prilocaine