Microbial contamination and preservation efficacy of cough preparations.
Cough syrups, manufactured by four different Jordanian pharmaceutical companies, were examined for microbial contents and efficacy of preservation from fungal and bacterial contamination. Five per cent of the tested samples were found to be contaminated by Candida albicans and 30% of the products examined did not comply with the pharmacopoeial requirements for optimal preservation from fungal contamination. All the products tested were free from bacteria and were efficiently preserved against accidental bacterial contamination.
Na'was
T E
TE
Faculty of Medicine, Jordan University of Science and Technology, Irbid.
Salem
M S
MS
Alkaysi
H N
HN
D000996:Antitussive Agents; D001419:Bacteria / Q000302:isolation & purification; D002176:Candida albicans / Q000302:isolation & purification; D004340:Drug Contamination / Q000706:statistics & numerical data*; D007597:Jordan; D011310:Preservatives, Pharmaceutical / Q000494:pharmacology*
D000996:Antitussive Agents; D011310:Preservatives, Pharmaceutical