title: [Recombinant human alfa2-interferon (reaferon) in ointment form in the treatment of various diseases of the skin and mucosa].
abstract: Clinical trials of the gene engineered human alpha 2-interferon as ointment were performed. The ointment was used in the treatment of patients with relapsing herpes of various localization, relapsing aphthous stomatitis and pemphigus vulgaris. It was shown that the ointment was harmless and its therapeutic effect was favourable. The preparation is recommended for introduction into the practice of public health.
authors.affiliation: Institute of Immunology, Ministry of Medical Industry of the USSR, Moscow Region.
authors.forename: V V
authors.initials: VV
authors.lastname: Parfenov
authors.forename: V N
authors.initials: VN
authors.lastname: Grebeniuk
authors.forename: E I
authors.initials: EI
authors.lastname: Abramova
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Voronin
authors.forename: V V
authors.initials: VV
authors.lastname: Bumialis
authors.forename: T N
authors.initials: TN
authors.lastname: Volodina
authors.forename: L A
authors.initials: LA
authors.lastname: Denisov
mesh_terms: D000328:Adult; D005260:Female; D006561:Herpes Simplex / Q000188:drug therapy; D006801:Humans; D007370:Interferon Type I / Q000009:adverse effects / Q000627:therapeutic use*; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D008297:Male; D008875:Middle Aged; D009092:Mucous Membrane / Q000187:drug effects; D009824:Ointments; D010392:Pemphigus / Q000188:drug therapy; D011994:Recombinant Proteins; D012871:Skin Diseases / Q000188:drug therapy*; D013281:Stomatitis, Aphthous / Q000188:drug therapy
chemical_list: D007370:Interferon Type I; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D009824:Ointments; D011994:Recombinant Proteins
vernacular_title: Gennoinzhenernyĭ chelovecheskiĭ interferon al'fa-2 (reaferon) v vide mazi pri lechenii nekotorykh zabolevaniĭ kozhi i slizistykh obolochek.