title: Comparative in vitro activities of newer quinolones against Pseudomonas species and Xanthomonas maltophilia isolated from patients with cancer.
abstract: The in vitro susceptibilities of three Pseudomonas species (Pseudomonas aeruginosa, Pseudomonas putida, and Pseudomonas fluorescens) and Xanthomonas maltophilia to quinolone antimicrobial agents were determined. Several newer agents, particularly PD117558, PD117596, PD127391, sparfloxacin (AT-4140), A-56620, and temafloxacin, were active against Pseudomonas species. X. maltophilia isolates were generally less susceptible than were Pseudomonas isolates but were inhibited by some of the newer quinolones.
authors.affiliation: Department of Medical Specialties, University of Texas M.D. Anderson Cancer Center, Houston 77030.
authors.forename: K V
authors.initials: KV
authors.lastname: Rolston
authors.forename: M
authors.initials: M
authors.lastname: Messer
authors.forename: D H
authors.initials: DH
authors.lastname: Ho
mesh_terms: D042462:4-Quinolones; D000890:Anti-Infective Agents / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D009369:Neoplasms / Q000382:microbiology*; D011549:Pseudomonas / Q000187:drug effects* / Q000302:isolation & purification; D014974:Xanthomonas / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D042462:4-Quinolones; D000890:Anti-Infective Agents