Ephedrine as a marker of intravascular injection in laboring parturients.
Thirty healthy laboring parturients were randomly chosen to receive either normal saline (NS), ephedrine 10 mg (EPH-10), or ephedrine 15 mg (EPH-15) intravenously. Changes in maternal heart rate and blood pressure and fetal heart rate were monitored. A clinically useful and statistically significant (less than 0.001) increase in systolic blood pressure of 10 torr or more occurred in all 10 patients in the EPH-15 group. There was no adverse fetal outcome. Transient fetal tachycardia was seen in three fetuses in the EPH-15 group.
Cherala
S R
SR
Cooper Green Hospital, University of Alabama, Birmingham.
Mehta
D
D
Greene
R
R
D000767:Anesthesia, Epidural; D000773:Anesthesia, Obstetrical; D001794:Blood Pressure / Q000187:drug effects; D004809:Ephedrine; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006340:Heart Rate, Fetal / Q000187:drug effects; D006801:Humans; D007275:Injections, Intravenous / Q000009:adverse effects; D007743:Labor, Obstetric; D011247:Pregnancy
D004809:Ephedrine