Design, properties, and effective use of the oral chelator L1 and other alpha-ketohydroxypyridines in the treatment of transfusional iron overload in thalassemia.
Kontoghiorghes
G J
GJ
Department of Haematology, Royal Free Hospital School of Medicine, London, United Kingdom.
D002614:Chelating Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use*; D000077543:Deferiprone; D015195:Drug Design; D006801:Humans; D007501:Iron / Q000097:blood*; D007502:Iron Chelating Agents; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use*; D011728:Pyridones / Q000627:therapeutic use*; D013789:Thalassemia / Q000628:therapy*; D065227:Transfusion Reaction
D002614:Chelating Agents; D007502:Iron Chelating Agents; D011725:Pyridines; D011728:Pyridones; D000077543:Deferiprone; D007501:Iron