title: Probabilities of orders in linkage calculations.
abstract: The present state of linkage estimation procedures is surveyed. When information on linkage between several loci on one chromosome is given in the form of lod scores or likelihoods, a method is developed for finding the probabilities of the different possible orders of the loci, and the distribution of the map distances between them. This depends largely on a Monte Carlo method of integrating the probabilities.
authors.affiliation: Galton Laboratory, University College London.
authors.forename: C A
authors.initials: CA
authors.lastname: Smith
mesh_terms: D005260:Female; D008040:Genetic Linkage; D005838:Genotype; D006801:Humans; D008126:Lod Score; D008297:Male; D009010:Monte Carlo Method