title: Single-channel and whole-cell currents in rat cerebellar granule cells.
abstract: The patch-clamp technique was used to study both whole-cell and single-channel currents in cultured rat cerebellar granule cells. In whole-cell recordings under voltage-clamp conditions 3 types of current were found; a transient inward sodium current and a transient and a sustained outward potassium current. Single-channel currents were recorded from both inside-out and outside-out membrane patches. Three types of potassium channel were identified; two non-inactivating channels with unit conductances of 160 and 60 pS and one inactivating channel of 20 pS. No calcium currents were detected.
authors.affiliation: Department of Biomedical Sciences, University of Tampere, Finland.
authors.forename: T
authors.initials: T
authors.lastname: Jalonen
authors.forename: S
authors.initials: S
authors.lastname: Johansson
authors.forename: I
authors.initials: I
authors.lastname: Holopainen
authors.forename: S S
authors.initials: SS
authors.lastname: Oja
authors.forename: P
authors.initials: P
authors.lastname: Arhem
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000818:Animals; D002478:Cells, Cultured; D002531:Cerebellum / Q000166:cytology / Q000502:physiology*; D008564:Membrane Potentials / Q000502:physiology; D015221:Potassium Channels / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D015221:Potassium Channels