title: [Surgical treatment of giant cell tumor of bone--a report of 50 cases].
abstract: Fifty cases of giant cell tumor of bone are reported in this paper. The peak age was 20-40 years (76%). 75% of the tumors occurred in the extremity of long bones, of which 36% were around the knee. These patients were treated by curettage and bone graft or bone cement filling, bloc resection with or without bone graft and amputation. In this series, the follow-up time was 4 months-22 years and 3 months, and recurrence rate was 34%. There was no marked relation between recurrence and grade of tumor (35% for Grade I, 31% for Grade II and 25% for 25% Grade III). Patients with Grade III tumor had much poorer prognosis than those with Grade I or II. The surgical treatment of giant cell tumor of bone, particularly tumor of the spine, is still a challenge for orthopedic surgeons. Bloc resection of the tumor might be the treatment of choice for giant cell tumor of bone.
authors.affiliation: Huashan Hospital, Shanghai Medical College.
authors.forename: J W
authors.initials: JW
authors.lastname: Zhou
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000473:pathology / Q000601:surgery*; D003475:Curettage; D005260:Female; D005266:Femoral Neoplasms / Q000473:pathology / Q000601:surgery; D005500:Follow-Up Studies; D005870:Giant Cell Tumors / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D013125:Spinal Neoplasms / Q000473:pathology / Q000601:surgery