title: Percutaneous transhepatic venous sampling of the pancreas in localizing insulinomas.
abstract: Fourteen percutaneous transhepatic venous samplings of the pancreas were performed in 13 patients. Ten patients undergoing 11 samplings were operated, while 3 patients were not operated. Surgical intervention disclosed a single tumor in 8 patients, a double tumor in 1 patient and diffuse hyperplasia in 1 patient. The method allowed correct localization of 5 insulinomas and correct regionalizing of 4 insulinomas in 9 of 10 small tumoral lesions. In 1 double localization of the pancreatic body percutaneous venous sampling only detected 1 lesion. In 1 case of diffuse hyperplasia of the pancreatic tail, the venous sampling was suggestive for a tumor in the pancreatic tail. The method appears to be highly accurate in diagnosing and localizing insulinomas of the pancreas. However, a need persists for 3-dimensional localization of the lesions to facilitate enucleation. Intraoperative ultrasound could become the method of choice for localization of insulinomas.
authors.affiliation: Department of Radiology, University Hospitals, KU Leuven, Belgium.
authors.forename: G
authors.initials: G
authors.lastname: Wilms
authors.forename: A L
authors.initials: AL
authors.lastname: Baert
authors.forename: A N
authors.initials: AN
authors.lastname: Dardenne
authors.forename: P
authors.initials: P
authors.lastname: Mathurin
authors.forename: P
authors.initials: P
authors.lastname: Staels
authors.forename: R
authors.initials: R
authors.lastname: Bouillon
authors.forename: J
authors.initials: J
authors.lastname: Lerut
authors.forename: T
authors.initials: T
authors.lastname: Lerut
mesh_terms: D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D001800:Blood Specimen Collection / Q000379:methods*; D001815:Bloodletting / Q000379:methods; D005260:Female; D006801:Humans; D007340:Insulinoma / Q000097:blood*; D008099:Liver; D008297:Male; D008642:Mesenteric Veins; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000097:blood*; D011169:Portal Vein; D013162:Splenic Vein
chemical_list: D001786:Blood Glucose