Adult T-cell leukemia/lymphoma of the tongue.
A case of posterior tongue lymphoma associated with adult T-cell leukemia (ATL) that occurred as a lesion in the lingual dorsal portion is reported in a 64-year-old woman. Initially, a diagnosis of Hodgkin's lymphoma was considered as no findings associated with ATL except lymphadenopathy and serum anti-ATLA antibodies were present. Combined radiotherapy and chemotherapy were administered with favorable results; however, 4 months later, Pneumocystis carinii pneumonia developed, and 2 months later, generalized lymphadenopathy and hypercalcemia evolved. At this time, a diagnosis of ATL was made. The patient died of renal dysfunction 6 months after the initial presentation. In suspected cases of ATL and malignant diseases of T-cell lineage, namely, malignant lymphoma and mycosis fungoides, the presence of HTLV-1 infection should be confirmed by testing for anti-ATLA antibodies.
Segami
N
N
Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Kyoto University, Japan.
Hosoda
M
M
Fukuda
M
M
Sugihara
T
T
Yahata
Y
Y
D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000473:pathology*; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis; D008875:Middle Aged; D014062:Tongue Neoplasms / Q000473:pathology*