Antistaphylococcal activity of pentamidine.
Pentamidine isethionate was bacteriostatic against Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, Streptococcus sanguis, Micrococcus sp., and Candida albicans. S. aureus was inhibited by concentrations of 16 to 64 micrograms/ml and killed by 64 to greater than or equal to 128 micrograms/ml. Staphylococcal killing was consistently greater in the presence of cations and was unaffected by methicillin resistance.
Libman
M D
MD
McGill University, Montreal General Hospital, Quebec, Canada.
Miller
M A
MA
Richards
G K
GK
D006801:Humans; D008826:Microbial Sensitivity Tests; D010419:Pentamidine / Q000494:pharmacology*; D013210:Staphylococcus / Q000187:drug effects*; D013211:Staphylococcus aureus / Q000187:drug effects; D013212:Staphylococcus epidermidis / Q000187:drug effects
D010419:Pentamidine