[Ovarian sex cord tumor with annular tubules--a report of 7 cases].
Seven cases of ovarian sex cord tumor with annular tubules are reported in this paper. All lesions occurred in the young (6-25 years of age with a mean of 15 years) without Poutz-Jeghers syndrome. Four cases had estrogenic hormonal imbalance and abdominal mass. Gross examination revealed that the tumors were unilateral with smooth surface. Except one, all showed varying degrees of cystic degeneration on section. The sections appeared as roe-like granular substance in a pale yellowish brown shade in the parenchymal region. Microscopic examination showed single or complex annular tubules with prominent basement membrane-like material around the tubules. Lipid in the cytoplasm and granulosa cell tumor-like differentiation were observed in isolated area of some cases. Ultrastructurally, Charcot-Battcher filaments were found in 1 case, indicating differentiation towards Sertoli's cells. The malignant potential of this tumor had been elucidated in the literature.
Li
X Z
XZ
81 Hospital, PLA, Nanjing.
D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000209:etiology / Q000473:pathology* / Q000648:ultrastructure