Inflammatory cells from the rat pleural cavity can activate the food-derived carcinogen MeIQx.
O'Farrell
F J
FJ
Department of Clinical Pharmacology, Royal Postgraduate Medical School, London, U.K.
Gooderham
N J
NJ
D000818:Animals; D001711:Biotransformation; D002273:Carcinogens / Q000493:pharmacokinetics*; D005506:Food Contamination; D066298:In Vitro Techniques; D007249:Inflammation / Q000378:metabolism; D009153:Mutagens / Q000493:pharmacokinetics; D010586:Phagocytes / Q000378:metabolism*; D010994:Pleura / Q000166:cytology; D011810:Quinoxalines / Q000493:pharmacokinetics*; D051381:Rats
D002273:Carcinogens; D009153:Mutagens; D011810:Quinoxalines; C036990:2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline