title: [Malignant schwannoma of the trigeminal nerve].
abstract: We report on diagnosis, treatment and clinical course of a solitary schwannoma of the trigeminal nerve with consecutive metastatic spread in a 45-year-old woman. The patient presented a temporal lobe syndrome with psychomotor seizures. Trigeminal nerve function was intact apart from a transient hypaesthesia in the mandibular branch. Assuming a meningioma the tumor was removed via a temporal approach. Secondary to the definitive histological diagnosis radiation therapy was performed. After that the patient was symptom-free. 4 months later a large recurrent tumor was found involving the cavernous sinus and the pterygopalatine fossa. In a second operation the tumor was resected intra- and extradurally through an infratemporal preauricular approach in cooperation with an oral and maxillo-facial surgeon. At this time multiple pulmonary metastases developed showing no response to polychemotherapy (EVI). The patient died 13 months after onset of the disease. Hitherto, only 5 cases of a primary malignant schwannoma of the trigeminal nerve have been published in the world literature.
authors.affiliation: Neurochirurgische Universitätsklinik Kiel.
authors.forename: E
authors.initials: E
authors.lastname: Kraus
authors.forename: W E
authors.initials: WE
authors.lastname: Braunsdorf
authors.forename: H
authors.initials: H
authors.lastname: Klinge
authors.forename: J P
authors.initials: JP
authors.lastname: Jensen
mesh_terms: D003390:Cranial Nerve Neoplasms / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D009442:Neurilemmoma / Q000175:diagnosis / Q000601:surgery*; D009460:Neurologic Examination; D011183:Postoperative Complications / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D012668:Trigeminal Ganglion / Q000601:surgery; D014276:Trigeminal Nerve / Q000473:pathology / Q000601:surgery*
vernacular_title: Malignes Schwannom des Nervus trigeminus.