title: The local recurrence of pigmented Spitz nevus after removal.
abstract: A seventeen-month-old female had a pigmented nodule on her left lower leg. The excised lesion was histologically diagnosed as a Spitz nevus, composed mainly of spindle-shaped melanocytes containing large amounts of melanin pigment. When nodular regrowth was seen at the operative site, the recurrent lesion was radically excised as nodular melanoma. However the histological characteristics of the second excised specimen were essentially the same as those in the initially excised one except for the existence of the newly formed collagen fibers, which may suggest an involuting stage in the central portion of the lesion.
authors.affiliation: Department of Dermatology, Tottori University School of Medicine, Yonago, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: M
authors.initials: M
authors.lastname: Mihara
authors.forename: S
authors.initials: S
authors.lastname: Shimao
authors.forename: K
authors.initials: K
authors.lastname: Taniguchi
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D007642:Keratosis; D007866:Leg; D008543:Melanins / Q000737:chemistry; D008544:Melanocytes / Q000473:pathology; D008545:Melanoma / Q000473:pathology; D009364:Neoplasm Recurrence, Local; D009508:Nevus, Pigmented / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*
chemical_list: D008543:Melanins