Renal stone formation following medical treatment of renal candidiasis.
Two very low birth weight infants who developed renal candidiasis with pelvicalyceal fungal concretions were treated medically with Amphotericin B and 5 Fluorocytosine. Two months following cessation of therapy, the fungal concretions decreased in size, became sterile and developed calcification in residual debris. The calcifications was still present at demise in one patient and at 18 months follow up in the other. These calcifications occurred in the absence of simultaneous furosemide therapy.
Cramer
B C
BC
Department of Radiology, Dr. Charles A. Janeway Child Health Centre, Newfoundland, St. John's, Canada.
Ozere
R
R
Andrews
W
W
D000666:Amphotericin B / Q000009:adverse effects*; D002177:Candidiasis / Q000150:complications / Q000188:drug therapy*; D005260:Female; D005437:Flucytosine / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases; D007669:Kidney Calculi / Q000139:chemically induced* / Q000209:etiology; D007674:Kidney Diseases / Q000150:complications / Q000188:drug therapy*
D000666:Amphotericin B; D005437:Flucytosine