[Process of fibrin depolymerization and non-enzymatic fibrinolysis in rabbits receiving atherogenic rations with addition of antioxidants].
The rabbits were kept on atherogenic ration for 2 months. This diet contained 0.3 mg/kg of cholesterol. In blood plasma of animals the authors observed a sharply reduced non-enzymatic fibrinolysis and depolymerization activity of non-stabilized fibrin. The addition of antioxidants and alpha-tocopherol (10 + 10 mg/kg) for 1 month to the atherogenic ration protected from the disturbance of the system hemostasis and normalized the depolymerization of non-stabilized fibrin.
Kudriashov
B A
BA
Pastorova
V E
VE
Liapina
L A
LA
Kondashevskaia
M V
MV
Kobozeva
L P
LP
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001780:Blood Coagulation Tests; D002791:Cholesterol, Dietary; D004036:Diet, Atherogenic; D005337:Fibrin / Q000032:analysis*; D005342:Fibrinolysis; D008297:Male; D011817:Rabbits; D014810:Vitamin E / Q000494:pharmacology*
D000975:Antioxidants; D002791:Cholesterol, Dietary; D014810:Vitamin E; D005337:Fibrin
Protsess depolimerizatsii fibrina i nefermentativnyĭ fibrinoliz u krolikov, poluchaiushchikh aterogennyĭ ratsion s dobavleniem antioksidantov.