title: Prenatal diagnosis of chromosomal disorders in Delhi.
abstract: Prenatal diagnosis of chromosomal disorders was carried out in 144 samples of amniotic fluid during 1986-1989. The commonest indication was pregnancy in women having a previous child with Down syndrome. Cultures were successful in 104 (72.2%) of 144 cases. Three (2.9%) abnormal karyotypes were detected. Of 53 women who had a previous child with Down syndrome, recurrence of trisomy 21 occur d in one (1.9%); while considering all abnormal karyotypes, there were three recurrences (2.9%).
authors.affiliation: Genetic Unit, All India Institute of Medical Sciences, New Delhi.
authors.forename: I C
authors.initials: IC
authors.lastname: Verma
authors.forename: S
authors.initials: S
authors.lastname: Mathew
authors.forename: R
authors.initials: R
authors.lastname: Elango
authors.forename: I
authors.initials: I
authors.lastname: Khanna
mesh_terms: D000328:Adult; D000649:Amniocentesis / Q000379:methods; D002869:Chromosome Aberrations / Q000175:diagnosis*; D025063:Chromosome Disorders; D005260:Female; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy