In vitro activities of ampicillin-sulbactam and cefoperazone-sulbactam against oxacillin-susceptible and oxacillin-resistant staphylococci.
Ampicillin-sulbactam and cefoperazone-sulbactam were tested against staphylococci that were collected from 40 different medical centers throughout the United States. Oxacillin-resistant strains were resistant to both drug combinations, but oxacillin-susceptible strains were uniformly susceptible. The latter included strains with borderline susceptibility to oxacillin and methicillin.
Barry
A L
AL
Clinical Microbiology Institute, Tualatin, Oregon 97062.
Jones
R N
RN
D000667:Ampicillin / Q000494:pharmacology*; D002438:Cefoperazone / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D004359:Drug Therapy, Combination / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods; D010068:Oxacillin / Q000494:pharmacology*; D012965:Sodium Chloride / Q000494:pharmacology; D013210:Staphylococcus / Q000187:drug effects*; D013407:Sulbactam / Q000494:pharmacology*
D012965:Sodium Chloride; D000667:Ampicillin; D002438:Cefoperazone; D013407:Sulbactam; D010068:Oxacillin