title: A multicenter evaluation of the Boehringer Mannheim/Hitachi 717 system.
abstract: Analytical performance of the Boehringer Mannheim/Hitachi 717 system was evaluated in a multicenter study involving seven different laboratories. Fifty-five methods including end point chemistries, enzymes, ISE, TDM, DAU, and specific protein assays were assessed over a 7 month period. Methods on the analyzer exhibited excellent precision with CVs less than 2% for within run precision, and CVs less than 3% for between day precision for most analytes; linearity, which met or exceeded manufacturer's claims; minimal sample and reagent carryover, and no significant interference from hemolysis; icterus; and lipemia. Recovery of the assigned value for 10 analytes in SRM 909 was acceptable. Comparison of methods with other BM/Hitachi analyzers resulted in slopes close to unity (0.93-1.06); comparison to other clinical chemistry analyzers yielded slopes of 0.88-1.07. Excellent performance and diverse method applications make the BM/Hitachi 717 analyzer a suitable instrument for work station consolidation.
authors.affiliation: Department of Chemistry, Massachusetts General Hospital, Boston 02114.
authors.forename: J
authors.initials: J
authors.lastname: Flood
authors.forename: R
authors.initials: R
authors.lastname: Liedtke
authors.forename: H
authors.initials: H
authors.lastname: Mattenheimer
authors.forename: L
authors.initials: L
authors.lastname: Rothouse
authors.forename: D
authors.initials: D
authors.lastname: Trundle
authors.forename: D
authors.initials: D
authors.lastname: Vroon
authors.forename: K
authors.initials: K
authors.lastname: Whisler
authors.forename: W
authors.initials: W
authors.lastname: Collinsworth
mesh_terms: D002138:Calibration; D002624:Chemistry, Clinical / Q000295:instrumentation*; D019411:Clinical Laboratory Techniques / Q000295:instrumentation*; D012015:Reference Standards; D015203:Reproducibility of Results