Single-channel and whole-cell currents in rat cerebellar granule cells.
The patch-clamp technique was used to study both whole-cell and single-channel currents in cultured rat cerebellar granule cells. In whole-cell recordings under voltage-clamp conditions 3 types of current were found; a transient inward sodium current and a transient and a sustained outward potassium current. Single-channel currents were recorded from both inside-out and outside-out membrane patches. Three types of potassium channel were identified; two non-inactivating channels with unit conductances of 160 and 60 pS and one inactivating channel of 20 pS. No calcium currents were detected.
Jalonen
T
T
Department of Biomedical Sciences, University of Tampere, Finland.
Johansson
S
S
Holopainen
I
I
Oja
S S
SS
Arhem
P
P
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D002478:Cells, Cultured; D002531:Cerebellum / Q000166:cytology / Q000502:physiology*; D008564:Membrane Potentials / Q000502:physiology; D015221:Potassium Channels / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains
D015221:Potassium Channels