Cytogenetic study of a patient with the Sézary syndrome.
A cytogenetic study was performed in a patient with Sézary syndrome, which is a T-helper lymphoproliferative disorder. Metaphases were obtained from a phytohemagglutinin-stimulated lymphocyte culture. Normal, hypodiploid (42 to 45 chromosomes) and hypotetraploid (84 to 88 chromosomes) cells were observed. Both abnormal cell lines showed the same abnormalities involving chromosomes 1, 2, 4, 6, 10, 11, 12, 14, 16, and 20.
Solé
F
F
Departament de Biologia Cellular i Fisiologia, Facultat de Ciències, Universitat Autònoma de Barcelona, Spain.
Tarrida
N
N
Coll
M D
MD
Caballin
M R
MR
De Miguel
A
A
Woessner
S
S
Egozcue
J
J
D000368:Aged; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D007621:Karyotyping; D011003:Ploidies; D012751:Sezary Syndrome / Q000235:genetics*