[Lipoproteins as coronary risk or non-risk indicators in elderly people].
Lipid and apolipoprotein (apo) levels were investigated in 98 (68 female, 30 male) subjects older than 85 years and 86 (59 female, 27 male) subjects aged 65-75 years. The mean cholesterol level of the long-lived persons who were free from overt degenerative arterial disease was 5.2 mmol/l and ranged markedly below the mean level of the population. Comparing both age groups, the triglyceride level of the high-age subjects was at 0.3 mmol/l, significantly lower; HDL-cholesterol and apo A-I at 0.15 mmol/l or 0.3 g/l were higher. Cholesterol, LDL-cholesterol, and apo B only tended to be lower in the higher age. Subjects suffering from degenerative arterial disease (circulatory disturbance, hypertonia, diabetes mellitus), especially the long-lived group, had a more marked unfavorable lipoprotein profile. Subjects over 85 years (13%) had markedly less disturbance in lipoprotein metabolism of high atherogenic potency (hyper-beta-, hypo-alpha-lipoproteinemia) than did subjects 65-75 years old (23%). Hypertriglyceridemia is with 38% or rather 21% very frequent and seems to be of less atherogenic potency. Hyper-alpha-lipoproteinemia as anti-risk factor for coronary heart diseases was established more frequently in the long-lived group with 13% in comparison to 3.5% in those 65-75 years of age.
Herrmann
W
W
Zentrallabor des Bezirkskrankenhauses Meinigen.
Hanf
S
S
Lindhofer
H G
HG
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000097:blood*; D001053:Apolipoproteins / Q000097:blood; D002784:Cholesterol / Q000097:blood; D003327:Coronary Disease / Q000209:etiology*; D005260:Female; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood
D001053:Apolipoproteins; D008074:Lipoproteins; D014280:Triglycerides; D002784:Cholesterol
Lipoproteine als koronare Risiko- oder Antirisikoindikatoren bei alten Menschen.