title: A comparison of methodologies in detection of the anaerobic threshold.
abstract: Peak cardiopulmonary exercise performance is readily evaluated. The most appropriate methodology for assessment of submaximal exercise performance, however, is a subject of controversy. Therefore, we assessed the difference between conventional methodologies using standard criteria to estimate the onset of anaerobiosis and compared them with known gas exchange and blood lactate [( La]) concentrations. Oxygen uptake (VO2) was determined at both the gas exchange anaerobic threshold (ATge) and the lactate threshold (LaT) using the following three types of commonly used methodologies in a blinded fashion: 1) conventional techniques based on manual inspection of plots of gas exchange indexes and [La] versus time, 2) computerized linear regression analysis of two-segment model plots for VCO2 versus VO2 and log [La] versus log VO2, and 3) fixed values determining the VO2 at a respiratory exchange ratio (VCO2/VO2) of 1.00 and at an [La] of 2 mmol/l. Respiratory exchange data were collected on a breath-by-breath basis in 30 men with documented myocardial infarction. Simultaneously, arterial blood was sampled for [La] every 20 seconds during maximal exercise on an upright bicycle ergometer programmed for a continuous ramp protocol of 15 W/min. The mean (+/- SD) peak VO2 was 1,463 (+/- 312) ml/min. The mean (+/- SD) VO2 values for each method were as follows: (table; see text) These results indicate that a good positive correlation exists between the gas exchange and lactate data by all three approaches. The chosen fixed values yield the highest threshold detection for both ATge and LaT. Detection was lowest using regression analysis for LaT.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Cardiology Department, Central Hospital in Rogaland, Stavanger, Norway.
authors.forename: K
authors.initials: K
authors.lastname: Dickstein
authors.forename: S
authors.initials: S
authors.lastname: Barvik
authors.forename: T
authors.initials: T
authors.lastname: Aarsland
authors.forename: S
authors.initials: S
authors.lastname: Snapinn
authors.forename: J
authors.initials: J
authors.lastname: Karlsson
mesh_terms: D000368:Aged; D015308:Anaerobic Threshold; D005080:Exercise Test / Q000379:methods*; D006333:Heart Failure / Q000175:diagnosis*; D006801:Humans; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D008297:Male; D008955:Models, Cardiovascular; D011659:Pulmonary Gas Exchange / Q000502:physiology*; D012044:Regression Analysis
chemical_list: D007773:Lactates; D019344:Lactic Acid