[Immunophenotype of lymphocytic infiltrate in mycosis fungoides at the plaque stage and at the tumor stage. A comparative study].
An immunohistochemical study of 18 cases of mycosis fungoides (8 cases in tumor stage, 10 in plaque stage) is reported. Seven immunohistochemical parameters were set to evaluate the immunophenotype of the lymphocytes int he two stages of the disease. The results showed loss of differentiation and marked activation of the neoplastic lymphocytes with the progression of the disease from plaque to tumor stage.
Cerroni
L
L
Clinica Dematologica, Università de L'Aquila.
Peris
K
K
Torlone
G
G
Chimenti
S
S
D000911:Antibodies, Monoclonal; D006801:Humans; D007150:Immunohistochemistry; D016130:Immunophenotyping; D008214:Lymphocytes / Q000276:immunology*; D009182:Mycosis Fungoides / Q000276:immunology* / Q000473:pathology; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000276:immunology* / Q000473:pathology
D000911:Antibodies, Monoclonal
Immunofenotipo dell'infiltrato linfocitario nella micosi fungoide in stadio a placca ed in stadio tumorale. Studio comparativo.