[Cross-reactivity of milk proteins: statistical analysis of RAST results].
RIA dosages of specific IgE antibodies to cow milk, alpha-lactalbumin, beta-lactoglobulin, casein, cheddar and mould cheese were determined in 440 patients. Statistic analysis has been carried out with: 1) the linear regression and correlation coefficient r2: 2) U test of Mann-Whitney and then S test of Kendall Results show that casein has low allergenicity in comparison to other cow's milk proteins. It could be unnecessary to quantify specific IgE to cow milk and cheeses. From the observed data we could suppose that the formulas with casein/blood protein ratio similar to maternal milk may be more allergenic than casein based ones.
Di Berardino
L
L
Divisione di Pediatria, Presidio Ospedaliero di Bollate Milano, Italia.
Angrisano
A
A
Zatta
G
G
Fregoso
A
A
Bagliani
G
G
Compostella
R
R
D000293:Adolescent; D000328:Adult; D000818:Animals; D002364:Caseins / Q000276:immunology; D002611:Cheese; D002648:Child; D002675:Child, Preschool; D003429:Cross Reactions; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D007223:Infant; D007768:Lactalbumin / Q000276:immunology; D007782:Lactoglobulins / Q000276:immunology; D008297:Male; D016269:Milk Hypersensitivity / Q000276:immunology*; D008894:Milk Proteins / Q000276:immunology*; D011852:Radioallergosorbent Test; D013223:Statistics as Topic
D002364:Caseins; D007782:Lactoglobulins; D008894:Milk Proteins; D007073:Immunoglobulin E; D007768:Lactalbumin
Reattività crociata fra le proteine del latte con l'analisi statistica dei risultati del RAST.