title: A possible genetic component of obesity in childhood. Observations on acid phosphatase polymorphism.
abstract: Phenotypes of acid phosphatase with low enzymatic activity (ACP1 A and BA) are correlated with the highest degree of body mass increase observed in a sample of obese children. Since acid phosphatase probably functions as a flavin-mononucleotide phosphatase, differential modulation of flavo-enzyme activity and energy metabolism due to acid phosphatase genetic variability may explain the observed association.
authors.affiliation: Chair of Human Development, 2nd University of Rome School of Medicine, Italy.
authors.forename: N
authors.initials: N
authors.lastname: Lucarini
authors.forename: G
authors.initials: G
authors.lastname: Finocchi
authors.forename: F
authors.initials: F
authors.lastname: Gloria-Bottini
authors.forename: M
authors.initials: M
authors.lastname: Macioce
authors.forename: P
authors.initials: P
authors.lastname: Borgiani
authors.forename: A
authors.initials: A
authors.lastname: Amante
authors.forename: E
authors.initials: E
authors.lastname: Bottini
mesh_terms: D000135:Acid Phosphatase / Q000235:genetics*; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity / Q000235:genetics*; D010641:Phenotype; D011110:Polymorphism, Genetic
chemical_list: D000135:Acid Phosphatase