title: Endogenous alkaloids in man, VII: 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline--a potential chloral-derived indol alkaloid in man.
abstract: The trichloromethyl tetrahydro-beta-carboline 5, an imaginable, chloral-derived mammalian indol "alkaloid", was prepared in high yields and was shown to be formed even under mild, physiological conditions, in aqueous medium. For its detection in low concentrations, a chromatographic procedure was elaborated. Furthermore, its potential metabolite 8 was synthesized for the first time.
authors.affiliation: Institut für Organische Chemie, Universität Würzburg.
authors.forename: G
authors.initials: G
authors.lastname: Bringmann
authors.forename: A
authors.initials: A
authors.lastname: Hille
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D002243:Carbolines / Q000138:chemical synthesis / Q000737:chemistry*; D006801:Humans
chemical_list: D000470:Alkaloids; D002243:Carbolines; C067372:1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline