[Kinetics of aliphatic alcohols (methanol, propanol-1 and isobutanol) in the presence of alcohol in the human body].
I. In several experiments the kinetics and questionable mutial influences of Methanol, Propanol-1 and Isobutanol were examined while Ethanol was present. II. In five different experiments 30 persons got separate congeners (7 mg Methanol/kg body weight, 5 mg Propanol-1/kg body weight, 5 mg Isobutanol/kg body weight) with 0.8 g Ethanol/kg body weight. The times of drinking took both 30 and 60 minutes. Blood samples were taken partly half hourly, partly every quarter of an hour while the experiments took 4 to 9.5 hours. III. Apart from shown exceptions the curves of the Ethanol concentrations during the phases of elimination showed the familiar linear slope, whereas the corresponding Methanol concentrations went up on average of 0.17 mg/kg/hour. Propanol-1 as well as Isobutanol took exponential courses in their phases of elimination. The corresponding results have been shown and discussed in detail.
Bilzer
N
N
Abteilung Rechtsmedizin der Christian-Albrechts-Universität Kiel.
Schmutte
P
P
Jehs
M
M
Penners
B M
BM
D000433:1-Propanol / Q000493:pharmacokinetics*; D000328:Adult; D000428:Alcohol Drinking / Q000097:blood*; D000440:Butanols / Q000493:pharmacokinetics*; D000431:Ethanol / Q000493:pharmacokinetics*; D005260:Female; D006801:Humans; D008297:Male; D008657:Metabolic Clearance Rate / Q000502:physiology; D000432:Methanol / Q000493:pharmacokinetics*; D008875:Middle Aged
D000440:Butanols; D000431:Ethanol; C040507:isobutyl alcohol; D000433:1-Propanol; D000432:Methanol
Kinetik aliphatischer Alkohole (Methanol, Propanol-1 und Isobutanol) bei Anwesenheit von Athanol im menschlichen Körper.