title: [The determination of the concentration of antithrombin III in the urine].
abstract: The authors developed the special enzyme immunoassay technique for the detection of the urinary antitrombin III (AT-III) levels. Sensitivity of the method was 7.8 ng/ml. The study lasted for 2 hrs. The levels of AT-III were studied in the circadian human urine in health, in physiological and nephropathy-complicated pregnancy, as well as in patients with gastroduodenal ulcer-induced bleeding. There was a 34.1-fold increase in the urinary AT-III levels in pregnant females with Stages II-III nephropathy and a 17.3-fold increase in those who sustained the resection of the stomach, which could be explained by proteinuria and abnormal resorption of AT-III in the proximal tubules of the kidney.
authors.forename: O A
authors.initials: OA
authors.lastname: Markova
authors.forename: V V
authors.initials: VV
authors.lastname: Kalashnikov
authors.forename: L L
authors.initials: LL
authors.lastname: Parfenov
mesh_terms: D000990:Antithrombin III / Q000652:urine*; D002138:Calibration; D004381:Duodenal Ulcer / Q000150:complications / Q000652:urine; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007674:Kidney Diseases / Q000652:urine; D010438:Peptic Ulcer Hemorrhage / Q000652:urine; D011247:Pregnancy; D011248:Pregnancy Complications / Q000652:urine; D013276:Stomach Ulcer / Q000150:complications / Q000652:urine
chemical_list: D000990:Antithrombin III
vernacular_title: Opredelenie kontsentratsii antitrombina III v moche.