Clinical pharmacokinetic studies with lornoxicam.
Pharmacokinetic data from several studies in young and elderly human subjects are reviewed. Lornoxicam appears to be extensively metabolized and no unchanged drug has been found in the urine. It has a relatively short elimination half-life (about 4 hours), and no significant differences in pharmacokinetic data have been found between young and elderly volunteers.
Turner
P
P
Department of Clinical Pharmacology, St. Bartholomew's Hospital, London, UK.
Johnston
A
A
D000328:Adult; D000368:Aged; D000375:Aging / Q000378:metabolism; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000493:pharmacokinetics*; D006207:Half-Life; D006801:Humans; D010894:Piroxicam / Q000031:analogs & derivatives* / Q000493:pharmacokinetics
D000894:Anti-Inflammatory Agents, Non-Steroidal; D010894:Piroxicam; C059451:lornoxicam