Polydactyly in four generations of an Algerian family with variable metacarpo-phalangeal relationship in an individual.
We report an Algerian family in which four generations show polydactyly with variable numbers of metacarpals and phalanges. The extraordinary rearrangements of the metacarpals and phalanges shown in the X-rays are most unusual. The family is highly consanguineous. The mode of inheritance appears to be dominant with reduced penetrance and variable expression.
Sinha
A K
AK
Department of Orthopedic Surgery, Long Island College Hospital, Suny Health Science Center, Brooklyn.
Verma
R S
RS
D000328:Adult; D000462:Algeria; D003241:Consanguinity; D005385:Fingers / Q000002:abnormalities*; D005799:Genes, Dominant; D006801:Humans; D008297:Male; D008663:Metacarpus / Q000002:abnormalities*; D010375:Pedigree