Combined UVA-UVB versus UVB phototherapy for atopic dermatitis: a paired-comparison study.
In a paired-comparison study 30 patients with atopic dermatitis underwent treatment with a combination of UVA and UVB radiation (UVAB) on one side of the body and UVB on the other. Treatment was administered three times a week for a maximum of 8 weeks. Each patient was evaluated with respect to eight effect variables. Statistically significant differences in favor of UVAB were observed for all analyzed variables, namely total score (p = 0.002), pruritus score (p = 0.04), and overall evaluation score (p = 0.03). No statistically significant differences in healing rate were seen; 25 of 30 UVB-treated, and 26 of 30 UVAB-treated, body halves healed or were considerably improved. Patient preference was overwhelmingly in favor of UVAB; 23 of 24 patients who completed an evaluation form preferred this treatment. Only 1 of 24 preferred UVB.
Jekler
J
J
Department of Dermatology, University of Göteborg, Sahigren's Hospital, Sweden.
Larkö
O
O
D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D003876:Dermatitis, Atopic / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D008297:Male; D011897:Random Allocation; D013997:Time Factors; D014466:Ultraviolet Rays; D014467:Ultraviolet Therapy / Q000009:adverse effects / Q000295:instrumentation; D014945:Wound Healing