Review of published studies on single dose therapy of urinary tract infections.
The published studies of the use of single dose antimicrobial therapy for the treatment of urinary tract infection have been reviewed. In women and children a single dose of any of several antimicrobial agents was as effective as a course of treatment for uncomplicated urinary tract infections caused by Escherichia coli. Trimethoprim or co-trimoxazole are currently the preferred agents for single dose therapy. Failure of single dose therapy may prove to be a simple guide as to the need for further urinary tract investigation or more intensive therapy. Single dose antimicrobial therapy is now the treatment of choice for uncomplicated urinary tract infections.
Bailey
R R
RR
Department of Nephrology, Christchurch Hospital, New Zealand.
D000892:Anti-Infective Agents, Urinary / Q000008:administration & dosage* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D005260:Female; D049673:History, 20th Century; D006801:Humans; D013997:Time Factors; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000266:history
D000892:Anti-Infective Agents, Urinary