title: Ingestion of carbohydrates varying in complexity produce differential brain responses.
abstract: Variations in the complexity of carbohydrate substances were studied with respect to their differential effects on brain function. Glucose, sucrose, fructose and corn starch were each administered as part of an oral carbohydrate tolerance test during 17 test trials. Brain EEG changes and blood glucose levels were monitored concurrently throughout a 5 hour period. The glucose solution produced more substantial EEG effects than the other three carbohydrate solutions. Absolute blood glucose level was the primary determinant of electrocortical changes found predominantly in the left parietal-occipital and left temporal cortical regions. Implications for the study and evaluation of cognitive function were discussed.
authors.affiliation: NIDA-Addiction Research Center, Baltimore, Maryland 21224.
authors.forename: D H
authors.initials: DH
authors.lastname: Fishbein
authors.forename: R W
authors.initials: RW
authors.lastname: Thatcher
authors.forename: D S
authors.initials: DS
authors.lastname: Cantor
mesh_terms: D001921:Brain / Q000502:physiology*; D004040:Dietary Carbohydrates / Q000494:pharmacology*; D004569:Electroencephalography; D005632:Fructose / Q000494:pharmacology; D005947:Glucose / Q000494:pharmacology; D005951:Glucose Tolerance Test; D006801:Humans; D013213:Starch / Q000494:pharmacology; D013395:Sucrose / Q000494:pharmacology; D003313:Zea mays
chemical_list: D004040:Dietary Carbohydrates; D005632:Fructose; D013395:Sucrose; D013213:Starch; D005947:Glucose