title: CAF-603: a new antifungal carotane sesquiterpene. Isolation and structure elucidation.
abstract: A new antifungal compound, CAF-603, was isolated from the culture broth of Gliocladium virens IFO 9166. The structure of compound 1 has been elucidated by spectroscopic methods that also allowed the relative stereochemistry to be assigned. CAF-603 [1] was active against yeasts and dermatophytes.
authors.affiliation: Research Institute, Taisho Pharmaceutical, Saitama-ken, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Watanabe
authors.forename: M
authors.initials: M
authors.lastname: Yamagishi
authors.forename: T
authors.initials: T
authors.lastname: Mizutani
authors.forename: H
authors.initials: H
authors.lastname: Kondoh
authors.forename: S
authors.initials: S
authors.lastname: Omura
authors.forename: K
authors.initials: K
authors.lastname: Hanada
authors.forename: K
authors.initials: K
authors.lastname: Kushida
mesh_terms: D000935:Antifungal Agents / Q000302:isolation & purification*; D002176:Candida albicans / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D003904:Mitosporic Fungi / Q000032:analysis*; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000494:pharmacology*
chemical_list: D000935:Antifungal Agents; D012717:Sesquiterpenes; C067644:CAF 603