Presentation and management of an acute caffeine overdose.
A one-year-old white female ingested approximately two to three grams of caffeine (200-300 mg/kg). The patient survived the ingestion with a maximum caffeine concentration of 385 micrograms/ml four hours postingestion. The child developed ventricular arrhythmias, seizures, metabolic disturbances, and severe pulmonary edema. She survived without apparent long-term sequelae despite having reached a serum caffeine concentration that is the second highest reported level in a survivor.
Dietrich
A M
AM
Ohio State University.
Mortensen
M E
ME
D002110:Caffeine / Q000506:poisoning*; D062787:Drug Overdose / Q000628:therapy; D005260:Female; D006801:Humans; D007223:Infant; D012128:Respiratory Distress Syndrome / Q000139:chemically induced; D012640:Seizures / Q000139:chemically induced; D013610:Tachycardia / Q000139:chemically induced
D002110:Caffeine