title: POEMS syndrome: a case report.
abstract: A case of POEMS syndrome in a 43-year-old male with polyneuropathy, osteolytic lesion of the basin due to solitary IgA-lambda plasmacytoma, cutaneous scleroderma-like changes, diffuse lymphadenopathy and hepatosplenomegaly is described. Liver biopsy showed a regenerative process of the parenchyma without laboratory and histologic evidence of necrosis. A peculiar finding was the onset of a right hemiparesis in the absence of signs of vascular disease or other predisposing factors. The possible links between the peculiar elements of the POEMS syndrome are briefly analyzed and discussed.
authors.affiliation: Department of Medicine, University of Sassari, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Bisail
authors.forename: A
authors.initials: A
authors.lastname: Cossu
authors.forename: G
authors.initials: G
authors.lastname: Massarelli
authors.forename: F
authors.initials: F
authors.lastname: Tanda
authors.forename: V
authors.initials: V
authors.lastname: Agnetti
authors.forename: S
authors.initials: S
authors.lastname: Traccis
authors.forename: L
authors.initials: L
authors.lastname: Cassisa
authors.forename: M V
authors.initials: MV
authors.lastname: Puliga
authors.forename: E
authors.initials: E
authors.lastname: Bartoli
mesh_terms: D001859:Bone Neoplasms / Q000150:complications*; D005871:Castleman Disease / Q000150:complications; D003711:Demyelinating Diseases / Q000209:etiology*; D006529:Hepatomegaly / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010014:Osteolysis; D010257:Paraneoplastic Syndromes / Q000209:etiology*; D010954:Plasmacytoma / Q000150:complications*; D013163:Splenomegaly / Q000209:etiology