title: Successful treatment of sarcoidosis-associated pulmonary hypertension with corticosteroids.
abstract: We report a case of sarcoidosis presenting with cor pulmonale of a greater severity than would be expected from the degree of hypoxia and pulmonary fibrosis. Right heart catheterization revealed that mean pulmonary artery pressure was markedly increased (42 mm Hg), was not reduced by supplemental oxygen, but was reduced significantly (25 mm Hg) after 16 weeks of therapy with corticosteroids. Improvement in symptoms and pulmonary function was maintained for an 18-month period of observation after cessation of corticosteroid therapy.
authors.affiliation: Department of Medicine, University of Colorado Health Sciences Center, Denver.
authors.forename: D M
authors.initials: DM
authors.lastname: Rodman
authors.forename: J
authors.initials: J
authors.lastname: Lindenfeld
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy* / Q000209:etiology; D008171:Lung Diseases / Q000150:complications*; D011241:Prednisone / Q000627:therapeutic use*; D012507:Sarcoidosis / Q000150:complications*
chemical_list: D011241:Prednisone