Alpha-diketone and alpha-keto ester derivatives of N-protected amino acids and peptides as novel inhibitors of cysteine and serine proteinases.
Angelastro
M R
MR
Merrell Dow Research Institute, Cincinnati, Ohio 45215.
Mehdi
S
S
Burkhart
J P
JP
Peet
N P
NP
Bey
P
P
D000596:Amino Acids / Q000494:pharmacology*; D002154:Calpain / Q000037:antagonists & inhibitors*; D055598:Chemical Phenomena; D002621:Chemistry; D002918:Chymotrypsin / Q000037:antagonists & inhibitors*; D004151:Dipeptides / Q000494:pharmacology*; D004952:Esters / Q000494:pharmacology; D007659:Ketones / Q000494:pharmacology*; D015394:Molecular Structure; D011480:Protease Inhibitors / Q000494:pharmacology
D000596:Amino Acids; D004151:Dipeptides; D004952:Esters; D007659:Ketones; D011480:Protease Inhibitors; D002918:Chymotrypsin; D002154:Calpain