title: Occurrence of MRI abnormalities in patients with isolated optic neuritis.
abstract: 24 patients with clinically isolated optic neuritis (ON) were examined with MRI. Only 5 patients (22.9%) had a normal MRI scan. The number of detected clinically silent lesions ranged from 0 to 38. They were mainly located in the frontal and parietal white matter. All patients with more than 3 lesions on MRI had pathological findings in CSF. There was no correlation between the number and location of lesions and age at onset of ON.
authors.affiliation: Max-Planck-Society, Clinical Research Unit for Multiple Sclerosis, FRG.
authors.forename: D
authors.initials: D
authors.lastname: Städt
authors.forename: L
authors.initials: L
authors.lastname: Kappos
authors.forename: E
authors.initials: E
authors.lastname: Rohrbach
authors.forename: R
authors.initials: R
authors.lastname: Heun
authors.forename: M
authors.initials: M
authors.lastname: Ratzka
mesh_terms: D000328:Adult; D005260:Female; D005625:Frontal Lobe / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009902:Optic Neuritis / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D010296:Parietal Lobe / Q000473:pathology