Pediatric urological complications with intraoperative radiation therapy.
Intraoperative radiotherapy with variable energy electrons has been used as a supplemental boost to treat 6 children with locally advanced retroperitoneal malignancies. Of the patients 4 had treatment-related injuries to portions of the urinary tract within the intraoperative and external radiation fields. Three patients had significant renal impairment requiring surgical correction. The pathogenesis and management of treatment-induced injury to the urinary tract are discussed.
Ritchey
M L
ML
Department of Urology, Mayo Clinic, Rochester, Minnesota 55905.
Gunderson
L L
LL
Smithson
W A
WA
Kelalis
P P
PP
Kaufman
B H
BH
Telander
R L
RL
Evans
R G
RG
Kramer
S A
SA
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D007674:Kidney Diseases / Q000209:etiology* / Q000473:pathology; D008297:Male; D011832:Radiation Injuries / Q000473:pathology*; D011878:Radiotherapy / Q000009:adverse effects; D012186:Retroperitoneal Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D014515:Ureteral Diseases / Q000209:etiology* / Q000473:pathology