title: The chromatin fiber: structure and conformational transitions as revealed by optical anisotropy studies.
abstract: Structure and conformational transitions of the chromatin fiber as revealed by optical anisotropy studies are reviewed. The data in the literature do not allow a definite interpretation; in fact some of them are contradictory. The major findings are reported here and an attempt is made to analyse them with respect to the internal dynamics and the various models suggested for the organization of the chromatin fiber.
authors.affiliation: Institute of Molecular Biology, Bulgarian Academy of Sciences, Sofia.
authors.forename: S I
authors.initials: SI
authors.lastname: Dimitrov
authors.forename: V L
authors.initials: VL
authors.lastname: Makarov
authors.forename: I G
authors.initials: IG
authors.lastname: Pashev
mesh_terms: D002412:Cations / Q000494:pharmacology; D002843:Chromatin / Q000737:chemistry*; D004247:DNA / Q000737:chemistry* / Q000187:drug effects; D004563:Electrochemistry; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D011487:Protein Conformation; D013329:Structure-Activity Relationship; D014961:X-Ray Diffraction
chemical_list: D002412:Cations; D002843:Chromatin; D004247:DNA