[Effects of inactivated influenza vaccine on postvaccination immunity against tuberculosis].
The importance of inactivated influenza virus vaccines (IIVV) as a risk factor leading to a change of immunologic reactivity in persons earlier revaccinated with BCG once, twice or thrice was studied. The condition of T system was investigated by blast-transformation reaction with PPD-L and PHA in 1 and 3 months after administration of different types of IIVV. If all types of IIVV are administered, there is an inhibition of a specific activity of T cells with a certain stimulation of their nonspecific functions. The intensity of IIVV impact depends on the type, number, and duration of prior BCG vaccinations, as well as the initial condition of T-link.
Kalmykova
G N
GN
Dorofeeva
I K
IK
D000293:Adolescent; D001500:BCG Vaccine / Q000494:pharmacology; D002648:Child; D006801:Humans; D007252:Influenza Vaccines / Q000494:pharmacology*; D008213:Lymphocyte Activation; D013601:T-Lymphocytes / Q000276:immunology; D014376:Tuberculosis / Q000276:immunology*; D015164:Vaccines, Inactivated / Q000494:pharmacology
D001500:BCG Vaccine; D007252:Influenza Vaccines; D015164:Vaccines, Inactivated
Vliianie inaktivirovannykh grippoznykh vaktsin na postvaktsinal'nyĭ immunitet protiv tuberkuleza.