Antidiuretic effect of indapamide in central diabetes insipidus.
Indapamide produced a significant decrease in urinary output in three patients with central diabetes insipidus. The 24-h urinary volume was reduced from 5 to 2.3 l in a 39-year-old woman; from 11 to 4.3 l in a 30-year-old man, and from 16 to 9.2 l in a 40-year-old man receiving 2.5 mg of indapamide per day. To our knowledge, the antidiuretic effect of indapamide in central diabetes insipidus has not been reported previously.
Koçak
M
M
Department of Medicine, Cukurova University Medical Faculty Hospital, Adana, Turkey.
Karademir
B M
BM
Tetiker
T
T
D000328:Adult; D003919:Diabetes Insipidus / Q000188:drug therapy* / Q000503:physiopathology; D004231:Diuresis / Q000187:drug effects*; D005260:Female; D006801:Humans; D007190:Indapamide / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male
D007190:Indapamide