Serum cholesterol, high-density lipoprotein cholesterol and five-year survival in elderly people.
In the year 1982 serum cholesterol and high-density lipoprotein (HDL) cholesterol were measured in 535 people aged 85 years participating in a health survey screening. All subjects were living at home. During the 5-year follow-up, 186 (34.8%) of the subjects died. There was a J-shaped relation between serum cholesterol and mortality. Mortality was lowest at serum cholesterol 5.0-5.9 mmol/l for men and 7.0-7.9 mmol/l for women. The greatest mortality was observed in men with cholesterol greater than or equal to 6.0 mmol/l and in women with cholesterol greater than or equal to 8.0 mmol/l. There was a significant negative association of serum HDL cholesterol with mortality. Mortality was highest (53.3%) in men with serum HDL cholesterol less than 0.80 mmol/l. Mortality was low (16.5%) in women with serum HDL cholesterol greater than 1.8 mmol/l.
Nikkilä
M
M
Department of Clinical Sciences, University of Tampere, Finland.
Heikkinen
J
J
D000368:Aged; D000369:Aged, 80 and over; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D009026:Mortality; D015996:Survival Rate
D008076:Cholesterol, HDL; D002784:Cholesterol