A morphometric ultrastructural study of the nucleus of cerebellar granule cells.
A quantitative approach to the nuclear ultrastructure of cerebellar granule cells is described here. The study was made using conventional electron microscopy from cerebellar cortices of adult rats by means of a semiautomatic image analyzer. The basic observation is that the nuclei of mature granule cells constitute a homogeneous population in terms of morphometric and stereologic data; in fact, the volume density of condensed chromatin within the nuclei remains practically constant in all nuclear sections. These results seem to indicate the existence of a cell-specific nuclear morphometric phenotype which might be considered as an effective criterion for the typification of this cellular lineage.
Hervás
J P
JP
Department of Cytology and Histology, Faculty of Sciences, Autonomous University of Barcelona, Bellaterra, Spain.
Berciano
M T
MT
Silos
I
I
Lafarga
M
M
D000818:Animals; D002467:Cell Nucleus / Q000737:chemistry / Q000648:ultrastructure*; D002525:Cerebellar Cortex / Q000166:cytology* / Q000648:ultrastructure; D002843:Chromatin / Q000737:chemistry / Q000648:ultrastructure; D003594:Cytoplasmic Granules / Q000648:ultrastructure*; D004247:DNA / Q000032:analysis; D007091:Image Processing, Computer-Assisted; D008297:Male; D008854:Microscopy, Electron; D051381:Rats; D011919:Rats, Inbred Strains
D002843:Chromatin; D004247:DNA