Poststreptococcal glomerulonephritis flare-up in a patient with varicella infection.
A 15-year-old boy with poststreptococcal glomerulonephritis is described. During his recovery from nephritis he acquired varicella, which led to a flare-up of the glomerulonephritis with a transitory increase in blood pressure, body weight, and serum creatinine. We can only speculate on the pathogenetic mechanism of the flare-up. The glomerulonephritis may have been reactivated by immune complexes containing varicella antigens, or the varicella infection may have provoked immunologic changes leading to a new burst of immune complexes containing streptococcal antigens.
Fuhrer
J A
JA
Medizinische Klinik, Regionalspital Langenthal, Universität Basel, Schweiz.
Mihatsch
M J
MJ
Streuli
R A
RA
D000293:Adolescent; D002644:Chickenpox / Q000150:complications*; D005921:Glomerulonephritis / Q000150:complications / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D008297:Male; D013290:Streptococcal Infections / Q000150:complications*; D013297:Streptococcus pyogenes