title: [Study of genetic markers in families of patients with tuberculosis].
abstract: The article deals with findings of the study of HLA-genotype influence on tuberculosis susceptibility in 26 families with tuberculosis patients. It was found that sensitivity to tuberculosis in the examined families is associated with HLA-DR2 antigen. Segregation analyses conducted in the families of patients with tuberculosis revealed a correlation between the sensitivity to tuberculosis and inheritance of certain HLA haplotypes from the affected parents to their children with tuberculosis.
authors.forename: A Kh
authors.initials: AKh
authors.lastname: Rakhimov
authors.forename: L E
authors.initials: LE
authors.lastname: Pospelov
mesh_terms: D000328:Adult; D002648:Child; D004198:Disease Susceptibility; D005190:Family; D005260:Female; D005819:Genetic Markers; D005838:Genotype; D006680:HLA Antigens / Q000032:analysis; D015802:HLA-DR2 Antigen / Q000032:analysis; D006801:Humans; D008297:Male; D014376:Tuberculosis / Q000235:genetics*
chemical_list: D005819:Genetic Markers; D006680:HLA Antigens; D015802:HLA-DR2 Antigen
vernacular_title: Izuchenie geneticheskikh markerov v sem'iakh bol'nykh tuberkulezom.