[Hypersensitivity pneumonia caused by sulfonamides].
A 59-year-old man with Duhring's disease (herpetiform dermatitis) developed undulating fever and pulmonary infiltrates soon after sulfapyridine treatment was started. When the drug was discontinued, a positive provocation test unequivocally established the diagnosis of hypersensitivity pneumonia. There was also a cross-reaction with sulfonyldianiline (dapsone). This case illustrates the need of considering a hypersensitivity reaction as the cause of fever and (or) pulmonary infiltration during sulphonamide administration.
von Breska
B
B
Pneumologische Klinik Lenglern, Kreiskrenkenhaus an der Lieth, Bovenden.
Criée
C P
CP
Hüttemann
U
U
D003429:Cross Reactions; D003622:Dapsone / Q000009:adverse effects; D003874:Dermatitis Herpetiformis / Q000188:drug therapy; D004342:Drug Hypersensitivity; D006801:Humans; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000139:chemically induced*; D012130:Respiratory Hypersensitivity / Q000139:chemically induced*; D013424:Sulfanilamides / Q000009:adverse effects*; D013427:Sulfapyridine / Q000009:adverse effects* / Q000627:therapeutic use
D013424:Sulfanilamides; D003622:Dapsone; D013427:Sulfapyridine
Hypersensitivitätspneumonie durch Sulfonamide.