Cytogenetic analyses of three papillary carcinomas and a follicular adenoma of the thyroid.
Cytogenetic data of three papillary carcinomas and a follicular adenoma using direct preparations or cell cultures or both after 7 to 60 days in vitro are presented. Although karyotype of the follicular adenoma proved completely normal, in each of the three papillary carcinomas a modal chromosome number in the diploid range and a deleted 11q were observed. In case 1 the del(11)(q23) was associated with rearrangement of chromosome 1 and other marker chromosomes. Our results suggest that 11q deletion may be specific for papillary carcinoma of the thyroid.
Olah
E
E
Department of Pediatrics, Medical University, Debrecen, Hungary.
Balogh
E
E
Bojan
F
F
Juhasz
F
F
Stenszky
V
V
Farid
N R
NR
D000236:Adenoma / Q000235:genetics* / Q000473:pathology; D000293:Adolescent; D000328:Adult; D000368:Aged; D002291:Carcinoma, Papillary / Q000235:genetics* / Q000473:pathology; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D008297:Male; D013964:Thyroid Neoplasms / Q000235:genetics* / Q000473:pathology
D005819:Genetic Markers