[Beta-lipotropin and beta-endorphin in the hypothalamic syndrome].
Experiments were conducted on 90 non-strain male albino rats to study the possibility of compensating food intake and the functions related to its activity in disturbances caused by damage to the arcuate region of the hypothalamus. Neuropeptides beta-lipotropin (beta-LTP) and beta-endorphin were chosen as the compensation factors. The registered parameters were as follows: the volume of food and water intake, feeding and drinking behaviors, orientating-exploratory activity, comforting behavior, and the duration of sleep and drowsiness. It was established that destruction of the hypothalamic arcuate zone is attended by the formation of a specific syndrome including disorders of food and water intake and other forms of behavior. Intraventricular injections of beta-LPT and beta-endorphin under such conditions was conductive to the restoration of the disturbed functions and compensated for food intake and other related functions.
Dzhafarov
F I
FI
D000818:Animals; D007027:Hypothalamic Diseases / Q000503:physiopathology*; D008297:Male; D051379:Mice; D001615:beta-Endorphin / Q000502:physiology*; D008083:beta-Lipotropin / Q000502:physiology*
D001615:beta-Endorphin; D008083:beta-Lipotropin
Beta-lipotropin i beta-éndorfin pri gipotalamicheskom sindrome.