Resting energy expenditure in women: impact of obesity and body-fat distribution.
Postabsorptive resting metabolic rate (RMR) and diet-induced thermogenesis (DIT) were repeatedly assessed with an indirect calorimetric ventilated hood system in a group of 32 healthy premenopausal obese women, body fat percentage 46.4 +/- 0.9 (mean +/- SEM), age 38.5 +/- 0.9 years. RMR and DIT were also measured in a group of 10 healthy premenopausal non-obese women, body fat percentage 31.3 +/- 1.7, age 37.7 +/- 2.4 years. The obese women were subdivided according to the waist-to-hips girth ratio (WHR) into three groups with a different type of body fat distribution: A gluteal-femoral obese group (n = 10), WHR less than 0.79; an intermediate obese group (n = 10), 0.79 less than WHR less than 0.85; and an abdominal obese group (n = 12), WHR greater than 0.85. No significant differences were observed among the obese groups in age, body weight, body fat mass, and fat-free body mass. Body fat distribution was not associated with differences in DIT, pre- and postprandial respiratory quotients and substrate oxidation rates, but the abdominal obese women had significantly higher RMRs adjusted for age, fat mass, and fat-free body mass (6,075 +/- 200 kJ/d) in comparison with the gluteal-femoral obese women (5,502 +/- 205 kJ/d) and in comparison with obese women with an intermediate body fat distribution (5,517 +/- 193 kJ/d), but not in comparison with a non-obese control group, 6,790 +/- 261 kJ/d. It is concluded that within the total group of obese women, the non-abdominal obese can be characterized by relatively reduced resting metabolic rates in comparison with either the abdominal obese or with non-obese women.
Weststrate
J A
JA
Department of Human Nutrition, Wageningen Agricultural University, The Netherlands.
Dekker
J
J
Stoel
M
M
Begheijn
L
L
Deurenberg
P
P
Hautvast
J G
JG
D000273:Adipose Tissue / Q000378:metabolism*; D002001:Adipose Tissue, Brown / Q000378:metabolism; D000328:Adult; D000367:Age Factors; D001481:Basal Metabolism; D001786:Blood Glucose / Q000378:metabolism; D001823:Body Composition; D002153:Calorimetry, Indirect; D004041:Dietary Fats / Q000378:metabolism*; D004435:Eating; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D007408:Intestinal Absorption; D050356:Lipid Metabolism; D009765:Obesity / Q000097:blood / Q000378:metabolism*; D015657:Respiratory Transport; D012885:Skinfold Thickness; D013008:Somatotypes
D001786:Blood Glucose; D004041:Dietary Fats