[The effect of increased production of androgens on the development of body build morphology. Case report of an androgen-active tumor in a monozygotic twin].
The authors present an account on monozygotic twins where in one girl an androgen-active adenoma of the adrenal cortex during early puberty led to the development of the Morphogram of Body Build (Case-report of throughout the period of investigation intact from the hormonal aspect. Four years after resection of the tumour endocrine and anthropometric characteristics of the two sisters were evaluated: the hormonal status of both is normal, the somatic differences are manifested by a different final height, biacromial width and chest circumference. The results are conceived as a precedent for evaluation of risks associated with administration of anabolic steroids in children.
Lebl
J
J
II. dĕtská klinika, Univerzity Karlovy, Praha-Motol.
Zemková
D
D
Kopecký
A
A
Zikán
J
J
Marcek
P
P
D000236:Adenoma / Q000150:complications / Q000235:genetics / Q000378:metabolism*; D000306:Adrenal Cortex Neoplasms / Q000150:complications / Q000235:genetics / Q000378:metabolism*; D000728:Androgens / Q000378:metabolism*; D000886:Anthropometry; D001824:Body Constitution; D002648:Child; D004200:Diseases in Twins; D005260:Female; D006801:Humans; D014770:Virilism / Q000209:etiology* / Q000473:pathology
D000728:Androgens
Vliv nadprodukce androgenů na vývoj morfogramu tĕlesné stavby. (Kasuistika androgennĕ aktivního tumoru u monozygotního dvojcete).