title: [The mechanisms regulating pulse-wave spreading time in a biological feedback regimen in patients with borderline arterial hypertension and in healthy subjects].
abstract: The regulatory mechanisms of pulse transit time (PTT) during biofeedback training were studied by noninvasive cardiovascular monitoring in borderline hypertensive and normotensive subjects. Hemodynamic parameters were used as indirect indices of autonomous nervous system activity. All the patients were capable of increasing PTT. Systolic blood pressure demonstrated significant correlation with PTT. The effects were mediated by the different combinations of sympathetic and parasympathetic drives. In the initial 5 sessions, there was the most significant decrement of sympathetic, especially beta-adrenergic activity, expressed in the reduction of the myocardial contractility and cardiac output. In the retraining period (6 to 12 sessions), the leading role was played by the reduction of the arterial tone and total peripheral resistance. Respiratory arrhythmia rose in both cases as a result of the increased parasympathetic activity.
authors.forename: E M
authors.initials: EM
authors.lastname: Sokhadze
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Tsellarius
authors.forename: M B
authors.initials: MB
authors.lastname: Shtark
mesh_terms: D000328:Adult; D001676:Biofeedback, Psychology / Q000295:instrumentation / Q000502:physiology*; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000503:physiopathology* / Q000628:therapy; D008297:Male; D008838:Microcomputers; D011674:Pulse / Q000502:physiology*; D013997:Time Factors
vernacular_title: Mekhanizmy reguliatsii rasprostraneniia pul'sovoĭ volny v rezhime biologicheskoĭ obratnoĭ sviazi u patsientov s pogranichnoĭ arterial'noĭ gipertonieĭ i zdorovykh lits.