title: Comparative assessment of dual-photon absorptiometry and dual-energy radiography.
abstract: Dual-energy bone densitometry can be performed with two types of scanners. The traditional dual-photon absorptiometry (DPA) machines use an isotope source, whereas the newly introduced dual-energy radiography (DER) devices use an incorporated x-ray tube. The authors evaluated the performance of DPA and DER devices at their institution. The short-term precision error in vivo was 1.2% for femoral neck measurements with DER. Long-term precision error in vitro was reduced from 1.30% (DPA) to 0.44% (DER). The scanning time for both spine and hip measurements was reduced from 20-40 minutes to 6-7 minutes. Intraosseous fat sensitivity remained the same, at a level of 12 mg/cm2 apparent decrease of bone mineral density (BMD) per 10% fat by volume change, and for both devices there was no shift in BMD when phantom thickness was increased by 1.5 inches. The correlation of DPA and DER was high: r = .98 for the spine and r = .95 for the femoral neck. Correlation of DPA versus quantitative computed tomography (CT) (r = .83) and DER versus quantitative CT (r = .85) was good. The advent of DER represents a significant advance for the field of bone densitometry.
authors.affiliation: Department of Radiology, University of California, San Francisco 94143.
authors.forename: C C
authors.initials: CC
authors.lastname: Glüer
authors.forename: P
authors.initials: P
authors.lastname: Steiger
authors.forename: R
authors.initials: R
authors.lastname: Selvidge
authors.forename: K
authors.initials: K
authors.lastname: Elliesen-Kliefoth
authors.forename: C
authors.initials: C
authors.lastname: Hayashi
authors.forename: H K
authors.initials: HK
authors.lastname: Genant
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D015519:Bone Density; D003720:Densitometry / Q000379:methods; D005272:Femur Neck; D006801:Humans; D008159:Lumbar Vertebrae; D008961:Models, Structural; D015900:Radiography, Dual-Energy Scanned Projection