title: The effect of sustained release application of chlorhexidine on salivary levels of Streptococcus mutans in partial denture wearers.
abstract: The effect of a slow-releasing dosage (SRD) coating of chlorhexidine on the salivary levels of Streptococcus mutans and on plaque index scores in patients with removable partial dentures (RPD) was tested. The SRD proved to be effective in maintaining a low level of S. mutans counts after mechanical cleaning, as compared to a baseline established during the control period. Plaque index scores were lower following the treatment and correlated with the microbiological results. Our findings indicate that a single application of sustained-release chlorhexidine to removable partial dentures effectively maintains S. mutans levels as well as reducing the plaque score for a minimum period of 1 week.
authors.affiliation: Department of Oral Rehabilitation, Hebrew University of Jerusalem, Israel.
authors.forename: D
authors.initials: D
authors.lastname: Zyskind
authors.forename: D
authors.initials: D
authors.lastname: Steinberg
authors.forename: A
authors.initials: A
authors.lastname: Stabholz
authors.forename: M
authors.initials: M
authors.lastname: Friedman
authors.forename: M N
authors.initials: MN
authors.lastname: Sela
mesh_terms: D002710:Chlorhexidine / Q000008:administration & dosage*; D015169:Colony Count, Microbial; D003692:Delayed-Action Preparations; D003773:Dental Plaque / Q000382:microbiology; D003774:Dental Plaque Index; D003832:Denture, Partial, Removable; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012463:Saliva / Q000382:microbiology*; D013295:Streptococcus mutans / Q000187:drug effects*
chemical_list: D003692:Delayed-Action Preparations; D002710:Chlorhexidine