[Effect of an anthralin-containing hydrocolloid dressing in psoriasis vulgaris].
We investigated the effect of hydrocolloid dressings on the clearing of chronic plaque psoriasis. In comparison to a short-contact therapy with anthralin alone, following application of a hydrocolloid dressing accelerated the clearing of the plaques. This effect was significant after 3 weeks of therapy. A considerable improvement was achieved by the application of a hydrocolloid dressing containing anthralin. For this purpose anthralin in concentrations of 0.02 to 0.20 mg/cm2 was applied to the dressing immediately after it had been solved in acetone. The acetone was evaporated, and the anthralin was left on the dressing in a homogenous layer. In our study, the difference to short-contact anthralin was significant after 1, 2, 3, and 4 weeks of therapy. We conclude that this new way of anthralin application is suitable for the treatment of psoriasis and has therapeutical as well as technical advantages over a treatment with anthralin ointments.
Bunse
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Universitäts-Hautklinik Köln.
Merk
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D000328:Adult; D000875:Anthralin / Q000008:administration & dosage*; D047070:Bandages, Hydrocolloid; D003102:Colloids; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D009779:Occlusive Dressings; D011565:Psoriasis / Q000188:drug therapy*
D003102:Colloids; D000875:Anthralin
Effekt eines Anthralin-haltigen Hydrokolloid-Verbandes bei Psoriasis vulgaris.