title: Antibody persistence in splenectomized adults after pneumococcal vaccination.
abstract: 16 splenectomized adults, all vaccinated with a 14-valent pneumococcal vaccine (Pneumovax) 1978-79 had their pneumococcal antibody concentrations measured before and up to 10 years after vaccination. The antibody concentrations after vaccination declined to 71% in 2 years and remained at this level during the 10-year study period. Further studies are needed to see whether this applies to all vaccinated splenectomized adults.
authors.affiliation: WHO Collaborating Centre for Reference and Research on Pneumococci, Statens Seruminstitut, Copenhagen, Denmark.
authors.forename: H B
authors.initials: HB
authors.lastname: Konradsen
authors.forename: J L
authors.initials: JL
authors.lastname: Nielsen
authors.forename: F K
authors.initials: FK
authors.lastname: Pedersen
authors.forename: J
authors.initials: J
authors.lastname: Henrichsen
mesh_terms: D000907:Antibodies, Bacterial / Q000032:analysis* / Q000276:immunology; D001428:Bacterial Vaccines / Q000008:administration & dosage*; D006801:Humans; D022242:Pneumococcal Vaccines; D013156:Splenectomy; D013296:Streptococcus pneumoniae / Q000276:immunology*; D013997:Time Factors; D014611:Vaccination
chemical_list: D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines; D022242:Pneumococcal Vaccines