title: Ureteral obstruction due to blood clot following percutaneous renal biopsy: resolution with intraureteral streptokinase.
abstract: The nonsurgical approach to unilateral ureteral obstruction due to impaction of a blood clot is described. A patient with the nephrotic syndrome secondary to minimal change disease had gross hematuria and acute renal failure following percutaneous renal biopsy. After he responded to prednisone therapy, clot obstruction developed at the site of the percutaneous biopsied kidney, which was treated with intracaliceal infusion of streptokinase via a ureteral catheter. Complete resolution of the clot and the urinary tract obstruction was accomplished within 3 days. This approach appears to be the treatment of choice in upper urinary tract obstruction secondary to blood clots when simple ureteral catheter drainage is ineffective.
authors.affiliation: Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana 70112.
authors.forename: S M
authors.initials: SM
authors.lastname: Bergman
authors.forename: G D
authors.initials: GD
authors.lastname: Frentz
authors.forename: J D
authors.initials: JD
authors.lastname: Wallin
mesh_terms: D000328:Adult; D001706:Biopsy / Q000009:adverse effects*; D006406:Hematoma / Q000209:etiology; D006801:Humans; D007668:Kidney / Q000473:pathology*; D007674:Kidney Diseases / Q000209:etiology; D008297:Male; D011677:Punctures / Q000009:adverse effects; D011859:Radiography; D013300:Streptokinase / Q000008:administration & dosage* / Q000627:therapeutic use; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology; D014517:Ureteral Obstruction / Q000000981:diagnostic imaging / Q000209:etiology*
chemical_list: D013300:Streptokinase