title: Intrauterine insemination in subfertile couples.
abstract: Forty-three subfertile women were treated by intrauterine insemination with washed sperm. Among the couples, infertility was, in 7 cases due to cervical factor infertility, in 17 cases due to subfertile sperm quality, and 19 cases, unexplained. All women ovulated: 9 spontaneously, 26 where treated with clomiphene citrate and 8 with hMG-hCG. One hundred and sixty seven inseminations were performed in 90 ovulatory cycles. Six pregnancies were recorded (14%): three pregnancies among the cervical factor infertility group (42.8%), two among the couples with low sperm quality (11.7%) and one pregnancy in the group with unexplained infertility (5.2%). Thus, it can be concluded that IUI is effective for achieving pregnancy when unfavourable cervical factor is detected. The method is of doubtful value in cases of low sperm quality or unexplained infertility.
authors.affiliation: Institute for the Study of Fertility Serlin Maternity Hospital, Tel-Aviv Medical Centre, Sackler School of Medicine, Tel Aviv University, Israel.
authors.forename: H
authors.initials: H
authors.lastname: Yavetz
authors.forename: A
authors.initials: A
authors.lastname: Mosek
authors.forename: L
authors.initials: L
authors.lastname: Yogev
authors.forename: G
authors.initials: G
authors.lastname: Paz
authors.forename: Z T
authors.initials: ZT
authors.lastname: Homonnai
mesh_terms: D000328:Adult; D002582:Cervix Mucus / Q000502:physiology; D005260:Female; D006801:Humans; D007246:Infertility / Q000209:etiology / Q000628:therapy*; D007247:Infertility, Female / Q000628:therapy; D007248:Infertility, Male / Q000628:therapy; D007317:Insemination, Artificial, Homologous / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010062:Ovulation Induction; D011247:Pregnancy; D014599:Uterus