title: [Mutagenicity testing of some azo dyes used as food additives].
abstract: The mutagenicity of 4 azo dyes (Ponceau 4R, Amaranth, Sunset Yellow FCF and Tartrazine) that are widely used to color food has been evaluated. They were tested for mutagenicity in the Salmonella typhimurium plate-incorporation and preincubation assays. The standard plate-incorporation and preincubation assays performed directly on the dyes in the absence and presence of rat-liver S9. No mutagenic activity was seen for any of the azo dyes tested by using the standard tester strains, TA 98 and TA 100.
authors.affiliation: Hacettepe Universitesi, Fen Fakültesi, Biyoloji Bölümü, Moleküler Biyoloji Anabilim Dah.
authors.forename: A
authors.initials: A
authors.lastname: Izbirak
authors.forename: S
authors.initials: S
authors.lastname: Sümer
authors.forename: N
authors.initials: N
authors.lastname: Diril
mesh_terms: D000548:Amaranth Dye / Q000633:toxicity; D001391:Azo Compounds / Q000633:toxicity*; D005505:Food Coloring Agents / Q000633:toxicity*; D009152:Mutagenicity Tests; D009282:Naphthalenesulfonates; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics; D013645:Tartrazine / Q000633:toxicity
chemical_list: D001391:Azo Compounds; D005505:Food Coloring Agents; D009282:Naphthalenesulfonates; D000548:Amaranth Dye; C005842:6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt; D013645:Tartrazine; C576297:ponceau 4R
vernacular_title: Gidalara katilan bazi azo boyalarinin mutajenik etkilerinin test edilmesi.