Effect of gangliosides on memory formation of a conditioned avoidance response (CAR).
The influence of ganglioside application on the memory formation of an active conditioned avoidance response in rats was examined. Gangliosides produce retardation of the memory formation if applied immediately after the training session. If an interval of 2 h posttraining was used this effect was not observed.
Haselhorst
U
U
Institute of Pathobiochemistry, Academy of Medicine, Magdeburg, GDR.
Krusche
A
A
Schenk
H
H
Hantke
H
H
Grecksch
G
G
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects* / Q000502:physiology; D003213:Conditioning, Psychological / Q000187:drug effects* / Q000502:physiology; D005732:Gangliosides / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D008568:Memory / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D005732:Gangliosides