title: [The prevention of skin melanoma metastases to the regional lymph nodes].
abstract: Results are reported of the treatment of 82 patients with grade 1 melanoma of the skin of extremities and trunk. Endolymphatic chemotherapy was carried out after surgery. During the first postoperative year metastases to the regional lymph nodes developed in 15.7% of patients while in the control group of 333 patients metastases were found in 38.6%.
authors.forename: S I
authors.initials: SI
authors.lastname: Korovin
authors.forename: B A
authors.initials: BA
authors.lastname: Tolstopiatov
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D003606:Dacarbazine / Q000008:administration & dosage; D006801:Humans; D007272:Injections, Intralymphatic / Q000379:methods; D008207:Lymphatic Metastasis; D008545:Melanoma / Q000628:therapy*; D008727:Methotrexate / Q000008:administration & dosage; D011182:Postoperative Care / Q000379:methods; D011447:Prospidium / Q000008:administration & dosage; D012074:Remission Induction; D012878:Skin Neoplasms / Q000628:therapy*
chemical_list: D003606:Dacarbazine; D011447:Prospidium; D003520:Cyclophosphamide; D008727:Methotrexate
vernacular_title: Profilaktika metastazov melanomy kozhi v regionarnye limfaticheskie uzly.