Oral immunization with a polyvalent bacterial lysate can reduce mortality by infection with S. pneumoniae or influenza A in mice.
We investigated the effect of oral immunization in of mice which were exposed to S. pneumoniae or influenza A. The results suggest that oral immunization reduces the mortality rate. We believe that this effect is partially due to nonspecific defense mechanisms.
van Daal
G J
GJ
Dept. of Anesthesia, Erasmus University Rotterdam, The Netherlands.
So
K L
KL
Mouton
J W
JW
van 't Veen
A
A
Tenbrinck
R
R
Bergmann
K C
KC
Lachmann
B
B
D000284:Administration, Oral; D000818:Animals; D001427:Bacterial Toxins / Q000008:administration & dosage; D007116:Immunization, Passive; D009980:Influenza A virus / Q000276:immunology*; D051379:Mice; D009976:Orthomyxoviridae Infections / Q000517:prevention & control*; D011008:Pneumococcal Infections / Q000517:prevention & control*; D013296:Streptococcus pneumoniae / Q000276:immunology*
D001427:Bacterial Toxins