title: Systemic activity of ivermectin on the human body louse (Anoplura: Pediculidae).
abstract: Eighty-one to 100% of nymphs and females of the human body louse (Pediculus humanus humanus) that fed artificially on blood containing 2.5-10 ng ivermectin/ml died. The mortality of nymphs and female lice fed on rabbits treated with 200 micrograms/kg ivermectin was very high during the first two to three days, then declined sharply, reaching the level of the controls on day six. Nymphs were more sensitive than females. The average number of eggs laid by surviving females and the percentage that hatched from those eggs were lower than in controls.
authors.affiliation: Department of Parasitology, Hebrew University, Hadassah Medical School, Jerusalem, Israel.
authors.forename: K Y
authors.initials: KY
authors.lastname: Mumcuoglu
authors.forename: J
authors.initials: J
authors.lastname: Miller
authors.forename: L J
authors.initials: LJ
authors.lastname: Rosen
authors.forename: R
authors.initials: R
authors.lastname: Galun
mesh_terms: D000818:Animals; D000854:Anoplura; D005260:Female; D006801:Humans; D007559:Ivermectin / Q000627:therapeutic use*; D010373:Lice Infestations / Q000188:drug therapy*; D009758:Nymph; D011817:Rabbits
chemical_list: D007559:Ivermectin