Platelet-activating factor (PAF) and its relation to prostaglandins, leukotrienes and other aspects of arachidonate metabolism.
This article summarizes some of the previously reported findings regarding a lipid mediator known as platelet-activating factor (PAF), and briefly describes its effects on cells and tissues. The effects of PAF have also been considered in relation to certain products of arachidonate metabolism released in response to PAF.
Peplow
P V
PV
Department of Anatomy, Medical School, University of Otago, Dunedin, New Zealand.
Mikhailidis
D P
DP
D000818:Animals; D001095:Arachidonic Acids / Q000378:metabolism*; D001249:Asthma / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000378:metabolism; D015289:Leukotrienes / Q000378:metabolism*; D010195:Pancreatitis / Q000378:metabolism; D010972:Platelet Activating Factor / Q000378:metabolism*; D011453:Prostaglandins / Q000378:metabolism*
D001095:Arachidonic Acids; D015289:Leukotrienes; D010972:Platelet Activating Factor; D011453:Prostaglandins