[Manufacture and characterization of lyophilized suppositories].
Pharmaceutic usual hydrophilic macromolecular substances were investigated of usefulness to manufacture lyophilized suppositories contained propyphenazon or paracetamol. It was shown that gelatin, hydroxyethylcellulose and polyacrylic acid are able to form suitable solid structures.
Bornschein
M
M
Sektion Chemie, Wissenschaftsbereich Pharmazie, Humboldt-Universität, Berlin.
Gödicke
U
U
Voigt
R
R
Horsch
C
C
D000082:Acetaminophen / Q000008:administration & dosage; D000180:Acrylic Resins; D000983:Antipyrine / Q000008:administration & dosage / Q000031:analogs & derivatives; D002482:Cellulose / Q000031:analogs & derivatives; D004339:Drug Compounding; D004345:Drug Industry; D005612:Freeze Drying; D005780:Gelatin; D013488:Suppositories; D014783:Viscosity
D000180:Acrylic Resins; D013488:Suppositories; D000082:Acetaminophen; C006903:carbopol 940; D005780:Gelatin; D002482:Cellulose; C002283:hydroxyethylcellulose; C009077:propyphenazone; D000983:Antipyrine
Herstellung und Charakterisierung von lyophilisierten Suppositorien.