title: [Clinical evaluation of cefdinir in pediatric field].
abstract: We studied the clinical efficacy of cefdinir (CFDN), a new oral cephalosporin, in 18 children with ages 2 years and 4 months to 11 years and 4 months with pediatric infections. The diagnoses consisted of respiratory tract infections in 15 cases, impetigo in 2 and balanoposthitis in 1. Clinical efficacies were excellent in 11 patients and good in 7, with an efficacy rate of 100%. Bacteriologically, 9 (64.3%) of the 14 strains of clinical isolates were eradicated. No side effects nor abnormal laboratory findings were observed. We have concluded that CFDN is a useful antibiotic for the treatment of mild to moderate pediatric infections.
authors.affiliation: Department of Pediatrics, School of Medicine, Kyorin University.
authors.forename: K
authors.initials: K
authors.lastname: Mikuni
authors.forename: Y
authors.initials: Y
authors.lastname: Ishikawa
authors.forename: S
authors.initials: S
authors.lastname: Takahashi
authors.forename: H
authors.initials: H
authors.lastname: Hirosawa
authors.forename: H
authors.initials: H
authors.lastname: Ichihashi
mesh_terms: D000284:Administration, Oral; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification; D000077525:Cefdinir; D002511:Cephalosporins / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D007169:Impetigo / Q000188:drug therapy* / Q000378:metabolism / Q000382:microbiology; D008297:Male; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000378:metabolism / Q000382:microbiology
chemical_list: D002511:Cephalosporins; D000077525:Cefdinir