[Distribution of proteins in neural membranes as a factor of reabsorption of endoneural (interstitial) fluid].
An investigation on distribution of horseradish peroxidase (HP) product in the sciatic nerve membranes of albino rats, after HP intravenous injection, has been performed. Getting into the interstitial space of epineurium across the microvessel walls, HP spreads as far as the internal layer of the perineural membrane, forming a distinct gradient of concentration of protein at its border. In 60 min after injection of the tracer the value of the perineural-endoneural gradient for proteins is about 70-80% of the value of the plasma-endoneural gradient. A possible mechanism of the endoneural fluid evacuation, connected with various values of protein concentration in the endoneural space and within the nerve perineural membrane is discussed.
Banin
V V
VV
Gasymov
E K
EK
D000042:Absorption; D000818:Animals; D002199:Capillary Permeability / Q000502:physiology; D002462:Cell Membrane / Q000378:metabolism; D002463:Cell Membrane Permeability / Q000502:physiology; D004058:Diffusion; D005110:Extracellular Space / Q000378:metabolism*; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D051381:Rats; D012584:Sciatic Nerve / Q000098:blood supply / Q000378:metabolism* / Q000648:ultrastructure
D009419:Nerve Tissue Proteins
Raspredelenie proteinov v obolochkakh nerva kak faktor reabsorbtsii éndonevral'noĭ (interstitsial'noĭ) hidkosti.