title: Cranial postoperative site: assessment with contrast-enhanced MR imaging.
abstract: To define duration and patterns of postoperative contrast material enhancement, the authors evaluated magnetic resonance (MR) images obtained with gadolinium diethylenetriaminepentaacetic acid (DTPA) in 46 patients who had undergone major intracranial surgery. Intervals between surgery and MR imaging ranged from 1 day to 40 years (median, 1.3 years). Moderate or marked brain and dural enhancement was noted in nearly every patient imaged within 3 months of surgery, but all brain enhancement was gone by 1 year. Abnormal dural enhancement was noted in every patient imaged within 1 year of surgery and in approximately 50% at 1-2 years afterward. One patient had persistent mild enhancement of the dura 40 years after surgery. MR images revealed enhancement in several sites not frequently recognized on computed tomographic (CT) scans. Brain and meningeal enhancement with Gd-DTPA at cranial operative sites was more extensive and persisted much longer than is commonly seen on contrast-enhanced CT scans. Enhancement of the brain or pia mater does not normally last beyond 1 year, but dural enhancement may persist for decades.
authors.affiliation: Department of Radiology, Bowman Gray School of Medicine, Winston-Salem, NC 27103.
authors.forename: A D
authors.initials: AD
authors.lastname: Elster
authors.forename: D A
authors.initials: DA
authors.lastname: DiPersio
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology; D002648:Child; D003287:Contrast Media; D003399:Craniotomy; D004388:Dura Mater / Q000473:pathology; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008578:Meninges / Q000473:pathology; D009942:Organometallic Compounds; D004369:Pentetic Acid; D011183:Postoperative Complications / Q000175:diagnosis*; D011184:Postoperative Period; D011446:Prospective Studies; D012886:Skull / Q000473:pathology*; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA