title: [The clinical use of sodium hyaluronate eyedrops as a substitute for tears].
abstract: The present paper reports on the curative effect of the 0.1% Sodium hyaluronate (Na-HA) eyedrops jointly manufactured by Guangzhou Red Cross Hospital and Guangzhou Institute of Medical & Pharmaceutical Industry. 70 cases were studied. There were kerato-conjunctivitis sicca, lagophthalmos corneal fluorescein diffuse punctate epithelial lesion caused by contact lens, and keratitis punctata superficialis. The results showed effective treatment which occupied 95.7%. In the discussion, the authors point out that Na-HA has the same stagnatisity and elasticity as biotears because of its adhesion to the corneal epithelium. Moreover, it has the water-retaining microsponge action similar to that of mucopolysaccharide. Hence, Na-HA has protective effects on corneal epithelium. Finally, the authors conclude that Na-HA eyedrop is so far the most ideal substitute for tears and superior to other artificial tears.
authors.affiliation: Department of Ophthalmology, Guangzhou Red Cross Hospital, China.
authors.forename: Z
authors.initials: Z
authors.lastname: He
authors.forename: S
authors.initials: S
authors.lastname: Han
authors.forename: Z
authors.initials: Z
authors.lastname: Zhen
authors.forename: X
authors.initials: X
authors.lastname: Ding
authors.forename: S
authors.initials: S
authors.lastname: Liang
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage* / Q000627:therapeutic use*; D007634:Keratitis / Q000188:drug therapy; D007638:Keratoconjunctivitis Sicca / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions; D013666:Tears
chemical_list: D009883:Ophthalmic Solutions; D006820:Hyaluronic Acid