Relevance of immuno-contraceptive vaccines for population control. II. Gamete antigens.
Some new information on the sperm and seminal plasma antigens which can induce responses which decrease fertility has been obtained. This recent development has not, however, brought the understanding of the subject to a stage where the production of a contraceptive antisperm vaccine for the female can be discussed realistically. Many laboratories are continuing the active investigation of the potentials of zona pellucida antigens for contraceptive approach. Also, passive immunization with human monoclonal antibodies promises to be an effective and safe method for short-term contraception and early pregnancy termination.
Kurpisz
M
M
Institute of Human Genetics, Polish Academy of Sciences, Pozhán.
D000595:Amino Acid Sequence; D000818:Animals; D000941:Antigens; D003269:Contraception, Immunologic / Q000379:methods*; D005260:Female; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000737:chemistry / Q000276:immunology; D008297:Male; D008969:Molecular Sequence Data; D011155:Population Control / Q000379:methods*; D013094:Spermatozoa / Q000201:enzymology / Q000276:immunology; D014612:Vaccines; D015044:Zona Pellucida / Q000276:immunology
D000941:Antigens; D007527:Isoenzymes; D014612:Vaccines; D007770:L-Lactate Dehydrogenase