title: [Clinical trial of the treatment of rheumatoid arthritis with TFX (thymus factor X)].
abstract: The results of rheumatoid arthritis treatment with the preparation TFX (extract of calf thymus) are reported. The drug was given to 11 patients with intense inflammatory process treated previously in typical fashion without evident improvement and in whom immunological studies demonstrated disturbances of cell-mediated and humoral response. The duration of treatment and observation was 6 months. In 9 patients clinical improvement was achieved. We observed no correlation between clinical improvement and immunological indices besides statistically significant changes of skin tests. The results (assessment of health state, laboratory investigations) encourage to TFX use in the treatment of rheumatoid arthritis.
authors.affiliation: Oddziału Reumatologicznego w Gryfowie Sl., Katedry i Kliniki Endokrynologicznej Ak. Med., we Wrocławiu.
authors.forename: B
authors.initials: B
authors.lastname: Lasisz
authors.forename: Z
authors.initials: Z
authors.lastname: Zdrojewicz
authors.forename: W
authors.initials: W
authors.lastname: Dul
authors.forename: J
authors.initials: J
authors.lastname: Strychalski
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013949:Thymus Extracts / Q000627:therapeutic use*
chemical_list: D000893:Anti-Inflammatory Agents; C019108:TFX; D013949:Thymus Extracts
vernacular_title: Próba leczenia reumatoidalnego zapalenia stawów preparatem TFX (Thymus factor X).