Widespread cutaneous necrosis associated with cardiolipin antibodies.
Many clinical phenomena have been described in association with antiphospholipid antibodies, which are measured by a variety of techniques. The relationship of each assay is not completely clear, nor is it apparent which assay correlates best with the various clinical conditions. We describe a patient with anticardiolipin antibodies but without lupus inhibitor who had widespread cutaneous necrosis and underlying thrombosis in dermal blood vessels.
O'Neill
A
A
Royal Prince Alfred Hospital, Sydney, N.S.W., Australia.
Gatenby
P A
PA
McGaw
B
B
Painter
D M
DM
McKenzie
P R
PR
D000328:Adult; D000906:Antibodies / Q000032:analysis*; D001706:Biopsy; D002308:Cardiolipins / Q000276:immunology*; D005260:Female; D006801:Humans; D009336:Necrosis; D011239:Prednisolone / Q000627:therapeutic use; D012867:Skin / Q000098:blood supply / Q000473:pathology; D012871:Skin Diseases / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D013927:Thrombosis / Q000276:immunology
D000906:Antibodies; D002308:Cardiolipins; D011239:Prednisolone