Enhancement of natural resistance of mice to Rhodococcus equi infection by Dextran Sulfate 500.
The effect of intraperitoneal injection of Dextran Sulfate 500 (DS-500, 500,000 Mr) on the intravenous clearance and host resistance to Rhodococcus equi in mice was studied. Contrary to the results seen with Listeria monocytogenes, DS-500 enhanced murine resistance to R. equi and altered organ distribution and clearance.
Takai
S
S
Department of Animal Hygiene, School of Veterinary Medicine and Animal Sciences, Kitasato University, Aomori.
Yokoyama
Y
Y
Tsubaki
S
S
D000193:Actinomycetales Infections / Q000276:immunology* / Q000382:microbiology / Q000517:prevention & control; D000818:Animals; D016264:Dextran Sulfate / Q000494:pharmacology*; D005260:Female; D007113:Immunity, Innate / Q000187:drug effects; D008088:Listeriosis / Q000276:immunology; D051379:Mice; D012240:Rhodococcus / Q000276:immunology* / Q000302:isolation & purification; D014018:Tissue Distribution
D016264:Dextran Sulfate