[Serum antibodies to bovine retinal S antigen in the patients with uveitis and healthy subjects].
The antibodies to bovine S-Ag in sera were determined by ELISA in 43 patients with acute or chronic, anterior or panuveitis and in 32 healthy persons as controls. The results showed that the antibodies titers to bovine S-Ag in the patients with panuveitis were not different from those in the controls (P greater than 0.05). However the antibody titers to bovine S-Ag in the patients with anterior uveitis were significantly lower than those in the controls (0.01 less than P less than 0.05). It is suggested that there are naturally occurring antibodies to S-Ag in health persons. The relationship between antibodies to S-Ag and uveitis is discussed. It is indicated that natural antibodies to S-Ag may play a protective role in the healthy subjects.
Xie
C
C
Eye Research Institute, Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou, China.
Yang
P
P
Huang
X
X
D000293:Adolescent; D000328:Adult; D000818:Animals; D000906:Antibodies / Q000032:analysis*; D000941:Antigens / Q000276:immunology*; D019393:Arrestin; D001323:Autoantibodies / Q000097:blood*; D002417:Cattle; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay; D005136:Eye Proteins / Q000276:immunology*; D005260:Female; D006801:Humans; D008297:Male; D008565:Membrane Proteins / Q000276:immunology*; D008875:Middle Aged; D015864:Panuveitis / Q000276:immunology*; D014605:Uveitis / Q000276:immunology*; D014606:Uveitis, Anterior / Q000276:immunology
D000906:Antibodies; D000941:Antigens; D019393:Arrestin; D001323:Autoantibodies; D005136:Eye Proteins; D008565:Membrane Proteins