A note on the antibacterial properties of 3-(3'-isocyanocyclopent-2'-enylidene)propionic acid in the ovine rumen.
The concentration of 3-(3'-isocyanocyclopent-2'-enylidene)propionic acid after introduction into the ovine rumen declined by 50% during 30 min. Its antibacterial activity in the rumen could be demonstrated by the decline in numbers of cellulolytic rumen bacteria from about 10(6)/ml to about 10(2)/ml.
Brewer
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D
National Research Council of Canada, Atlantic Research Laboratory, Halifax, Nova Scotia.
Parkinson
V O
VO
Taylor
A
A
D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D003517:Cyclopentanes / Q000737:chemistry / Q000494:pharmacology*; D005260:Female; D016018:Least-Squares Analysis; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry / Q000494:pharmacology*; D012417:Rumen / Q000382:microbiology*; D012756:Sheep / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D003517:Cyclopentanes; D009570:Nitriles; C047864:3-(3-isocyanocyclopent-2-enylidene)propionic acid