Crystallization and preliminary X-ray diffraction results of snowdrop (Galanthus nivalis) lectin.
Well-ordered single crystals have been grown for a mannose-specific lectin from snowdrop (Galanthus nivalis) bulbs in the presence of methyl-alpha-D-mannoside. The space group symmetry is consistent with the orthorhombic space group P2(1)2(1)2(1). The unit cell parameters are a = 140.0 A, b = 64.7 A, c = 62.0 A. The asymmetric unit can accommodate a tetramer. The functional molecule (50,000 daltons) consists of four identical subunits and is highly specific for alpha 1,3-linked mannose oligosaccharides.
Wright
C S
CS
Department of Biochemistry and Molecular Biophysics, MCV/VCU, MCV Station, Richmond 23298-0001.
Kaku
H
H
Goldstein
I J
IJ
D003461:Crystallography; D027801:Galanthus; D037102:Lectins; D008358:Mannose / Q000378:metabolism; D037121:Plant Lectins; D010944:Plants; D011487:Protein Conformation; D014961:X-Ray Diffraction
D037102:Lectins; D037121:Plant Lectins; D008358:Mannose