[The cytotoxic effect of the thrombocytes from patients with mycosis fungoides and Kaposi's sarcoma].
The platelet cytotoxic action on tumor cells was studied in patients with mycosis fungoides and Kaposi's sarcoma. The findings evidence, that along with the known populations of cytotoxic effector cells, such as lymphocytes and monocytes, platelets may destroy tumor cells as well. Platelet ability to induce tumor cell lysis is essentially increased in mycosis fungoides patients treated according to scheme B. The data indicate that platelets from patients with mycosis fungoides and Kaposi's sarcoma are characterized by cytotoxic activity against AKL continuous tumor target cell line.
Faradzhev
Z G
ZG
Bolvacheva
A V
AV
Bykovskaia
S N
SN
D000293:Adolescent; D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000276:immunology*; D003601:Cytotoxicity Tests, Immunologic / Q000379:methods; D003602:Cytotoxicity, Immunologic / Q000276:immunology*; D006801:Humans; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000276:immunology*; D012514:Sarcoma, Kaposi / Q000276:immunology*; D012878:Skin Neoplasms / Q000276:immunology*; D014407:Tumor Cells, Cultured / Q000276:immunology
Tsitotoksicheskiĭ éffekt trombotsitov u bol'nykh gibovidnym mikozom i sarkomoĭ Kaposhi.