title: Cytogenetics of thyroid follicular adenomas.
abstract: We present the results of a cytogenetic study of three cases of follicular adenoma of the thyroid. All three cases had a numerical strongly abnormal karyotype with most abnormalities (eg, +4 or +5, +7, +9, +12, +16) in common, possibly indicating that this cluster of abnormalities might be specific for follicular adenomas. For benign tumors, the three cases showed a remarkably abnormal karyotype. These cases are another example of benign tumors with chromosomal abnormalities that might be specific for follicular adenomas.
authors.affiliation: Department of Pathology, State University of Groningen, The Netherlands.
authors.forename: E
authors.initials: E
authors.lastname: van den Berg
authors.forename: J W
authors.initials: JW
authors.lastname: Oosterhuis
authors.forename: B
authors.initials: B
authors.lastname: de Jong
authors.forename: J
authors.initials: J
authors.lastname: Buist
authors.forename: A
authors.initials: A
authors.lastname: Vos
authors.forename: A
authors.initials: A
authors.lastname: Dam
authors.forename: B
authors.initials: B
authors.lastname: Vermeij
mesh_terms: D000236:Adenoma / Q000235:genetics* / Q000473:pathology; D000328:Adult; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000235:genetics* / Q000473:pathology