title: Rapid diagnosis of streptococcal pharyngitis with enzyme immunoassay.
abstract: From June 1988 to May 1989, 444 throat swab specimens were tested with an enzyme immunoassay kit for rapid diagnosis of group A streptococcal pharyngitis. The results were compared with those of throat culture method. The rapid test was positive in 37 of 42 culture-positive specimens and negative in 379 of 402 culture-negative specimens, thus yielding a total agreement of 93.7%, sensitivity 88.1%, specificity 94.7%, positive predictive value 61.7%, negative predictive value 98.7%. According to this practical application, we suggest that enzyme immunoassay test can be applied in outpatient clinics by busy pediatricians for rapid diagnosis of group A streptococcal pharyngitis.
authors.affiliation: Department of Pediatrics, National Taiwan University Hospital, Taipei, R.O.C.
authors.forename: J M
authors.initials: JM
authors.lastname: Chu
authors.forename: J M
authors.initials: JM
authors.lastname: Chen
authors.forename: M H
authors.initials: MH
authors.lastname: Wu
authors.forename: J Y
authors.initials: JY
authors.lastname: Hong
authors.forename: Y M
authors.initials: YM
authors.lastname: Wang
authors.forename: H H
authors.initials: HH
authors.lastname: Hsu
authors.forename: H C
authors.initials: HC
authors.lastname: Lue
mesh_terms: D000293:Adolescent; D000942:Antigens, Bacterial / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007124:Immunoenzyme Techniques; D010612:Pharyngitis / Q000175:diagnosis*; D013290:Streptococcal Infections / Q000175:diagnosis*; D013297:Streptococcus pyogenes / Q000276:immunology*
chemical_list: D000942:Antigens, Bacterial