title: Investigation of mechanistic consequences of natural structural variation within the cysteine proteinases by knowledge-based modelling and kinetic methods.
authors.affiliation: Department of Crystallography, Birkbeck College, University of London, U.K.
authors.forename: C M
authors.initials: CM
authors.lastname: Topham
authors.forename: J
authors.initials: J
authors.lastname: Overington
authors.forename: D
authors.initials: D
authors.lastname: Kowlessur
authors.forename: M
authors.initials: M
authors.lastname: Thomas
authors.forename: E W
authors.initials: EW
authors.lastname: Thomas
authors.forename: K
authors.initials: K
authors.lastname: Brocklehurst
mesh_terms: D000595:Amino Acid Sequence; D001185:Artificial Intelligence; D003198:Computer Simulation; D003546:Cysteine Endopeptidases / Q000737:chemistry* / Q000378:metabolism / Q000648:ultrastructure; D007700:Kinetics; D008958:Models, Molecular; D008969:Molecular Sequence Data; D010944:Plants / Q000201:enzymology; D013329:Structure-Activity Relationship
chemical_list: D003546:Cysteine Endopeptidases