Antimicrobial properties of N-carboxybutyl chitosan.
N-Carboxybutyl chitosan, a modified chitin of crustacean origin, displayed inhibitory, bactericidal, and candidacidal activities when tested against 298 cultures of various pathogens. Examination by electron microscopy showed that microbial cells exposed to N-carboxybutyl chitosan underwent marked morphological alterations. The data are of importance in defining the suitability of N-carboxybutyl chitosan as a wound dressing.
Muzzarelli
R
R
Institute of Biochemistry, Faculty of Medicine, University of Ancona, Italy.
Tarsi
R
R
Filippini
O
O
Giovanetti
E
E
Biagini
G
G
Varaldo
P E
PE
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000648:ultrastructure; D002473:Cell Wall / Q000187:drug effects; D002686:Chitin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D048271:Chitosan
D000900:Anti-Bacterial Agents; C067347:N-carboxybutyl chitosan; D002686:Chitin; D048271:Chitosan