title: Systemic malignant lymphoma presenting as bilateral exudative retinal detachment.
abstract: A 52-year-old male patient presented with a sudden painful loss of vision in both eyes. Ophthalmological examination revealed bilateral uveitis and marked bilateral nonrhegmatogenous retinal detachment near the optic disk. Systemic workup demonstrated IgM paraproteinemia. Abdominal ultrasound and computed tomographic studies revealed enlarged adrenal glands and irregular masses in the right hepatic lobe. Immune electrophoresis and multiple biopsy specimens established the diagnosis of systemic polymorphous immunocytoma. Polychemotherapy of this B-cell-derived type of non-Hodgkin's lymphoma led to a rapid remission and fast reduction of serous retinal detachment. We believe this is the first case of bilateral exudative retinal detachment as the initial ocular manifestation of systemic malignant B-cell lymphoma.
authors.affiliation: Medizinische Poliklinik, Universität München.
authors.forename: B A
authors.initials: BA
authors.lastname: Kormann
authors.forename: H
authors.initials: H
authors.lastname: Holzgreve
authors.forename: P G
authors.initials: PG
authors.lastname: Wolff-Kormann
authors.forename: K G
authors.initials: KG
authors.lastname: Riedel
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000175:diagnosis; D005134:Eye Neoplasms / Q000175:diagnosis / Q000556:secondary*; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis; D016393:Lymphoma, B-Cell / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis; D009887:Ophthalmoscopy; D012163:Retinal Detachment / Q000175:diagnosis*