title: Reduction of intrapulmonary shunt and resolution of digital clubbing associated with primary biliary cirrhosis after liver transplantation.
abstract: This report describes a patient with marked hypoxemia caused by intrapulmonary shunt associated with primary biliary cirrhosis. Liver transplantation resulted in resolution of digital clubbing and reduction of intrapulmonary shunt as demonstrated by normalization of room air arterial blood gases, reduction in shunt fraction and normalization of the indocyanine-enhanced echocardiogram and perfusion lung scan. This patient's course challenges the conventional notion that intrapulmonary shunting associated with chronic liver disease does not reverse after liver transplantation.
authors.affiliation: Department of Pulmonary Disease, Cleveland Clinic Foundation, Ohio 44195.
authors.forename: J K
authors.initials: JK
authors.lastname: Stoller
authors.forename: D
authors.initials: D
authors.lastname: Moodie
authors.forename: W A
authors.initials: WA
authors.lastname: Schiavone
authors.forename: D
authors.initials: D
authors.lastname: Vogt
authors.forename: T
authors.initials: T
authors.lastname: Broughan
authors.forename: E
authors.initials: E
authors.lastname: Winkelman
authors.forename: P K
authors.initials: PK
authors.lastname: Rehm
authors.forename: W D
authors.initials: WD
authors.lastname: Carey
mesh_terms: D000328:Adult; D001164:Arteriovenous Fistula / Q000601:surgery*; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000209:etiology / Q000601:surgery; D008105:Liver Cirrhosis, Biliary / Q000150:complications* / Q000601:surgery; D016031:Liver Transplantation; D010005:Osteoarthropathy, Secondary Hypertrophic / Q000209:etiology / Q000601:surgery*; D011651:Pulmonary Artery; D011652:Pulmonary Circulation; D011667:Pulmonary Veins