Pediatric HIV-1 disease in a Kampala Hospital.
Data of pediatric patients screened for HIV-1 infection between 1985 and 1989 were studied retrospectively in one of the major mission hospitals of Kampala (Uganda). Symptomatic HIV-1 infection was mainly acquired perinatally and was diagnosed in 87 per cent in children under 2 years of age. The mortality rate was 40 per cent in pediatric in-patients with symptomatic HIV-1 infection as compared to 12 per cent in overall pediatric inpatients. Symptoms included in the WHO clinical case definition for pediatric AIDS were mainly insensitive, unspecific and demonstrated a low positive predictive value. There was no difference in the prevalence of malaria and measles between HIV-1 positive and HIV-1 negative children.
Müller
O
O
League of Red Cross and Red Crescent Societies, Geneva, Switzerland.
Musoke
P
P
Sen
G
G
Moser
R
R
D002648:Child; D002675:Child, Preschool; D005260:Female; D015658:HIV Infections / Q000453:epidemiology* / Q000401:mortality / Q000503:physiopathology; D015497:HIV-1; D006786:Hospitals, Urban; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008921:Religious Missions; D012189:Retrospective Studies; D014454:Uganda / Q000453:epidemiology