title: The pattern of vertebral involvement in metastatic vertebral breast cancer.
abstract: The spine is a common site of bony metastasis. To date, studies have not identified the initial site and pattern of vertebral metastasis in a homogeneous group of patients. Twenty-seven magnetic resonance imaging studies performed on 25 patients with metastatic vertebral breast cancer were reviewed retrospectively. The location and extent of metastatic vertebral involvement were determined. The vertebral body is the most frequent initial site of metastatic seeding. Although radiographically an absent pedicle is often the first sign of metastatic disease, involvement of the pedicle is by direct extension from either the vertebral body or the posterior elements and is therefore a late occurrence in the disease process.
authors.affiliation: Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois.
authors.forename: P L
authors.initials: PL
authors.lastname: Asdourian
authors.forename: M
authors.initials: M
authors.lastname: Weidenbaum
authors.forename: R L
authors.initials: RL
authors.lastname: DeWald
authors.forename: K W
authors.initials: KW
authors.lastname: Hammerberg
authors.forename: R G
authors.initials: RG
authors.lastname: Ramsey
mesh_terms: D001943:Breast Neoplasms; D002574:Cervical Vertebrae / Q000473:pathology; D006801:Humans; D008159:Lumbar Vertebrae / Q000473:pathology; D008279:Magnetic Resonance Imaging; D012189:Retrospective Studies; D013125:Spinal Neoplasms / Q000175:diagnosis / Q000556:secondary*; D013904:Thoracic Vertebrae / Q000473:pathology