title: Scleroderma-like skin lesions in two patients with phenylketonuria.
abstract: Two patients with phenylketonuria and scleroderma-like skin lesions are presented. Since scleroderma is a rare collagen disease of childhood, the occurrence of these two disorders in the same patient does not seem to be coincidental but raises the possibility of a causal relationship. Improvement in the skin lesions of the patients after the commencement of a low-phenylalanine diet supports this hypothesis.
authors.affiliation: Division of Metabolism, Hacettepe University, Ankara, Turkey.
authors.forename: T
authors.initials: T
authors.lastname: Coşkun
authors.forename: I
authors.initials: I
authors.lastname: Ozalp
authors.forename: G
authors.initials: G
authors.lastname: Kale
authors.forename: S
authors.initials: S
authors.lastname: Göğüş
mesh_terms: D005260:Female; D006801:Humans; D007223:Infant; D010661:Phenylketonurias / Q000150:complications* / Q000628:therapy; D012594:Scleroderma, Localized / Q000150:complications* / Q000473:pathology; D012867:Skin / Q000473:pathology