Clonidine and nifedipine inhibit the abstinence but not the development of dependence in isolated guinea pig ileum.
Morrone
L A
LA
Institute of Pharmacology and Pharmacognosy, University of Rome La Sapienza.
Pimpinella
G
G
Romanelli
L
L
Piccinelli
D
D
Valeri
P
P
D000818:Animals; D003000:Clonidine / Q000494:pharmacology*; D004576:Electromyography; D006168:Guinea Pigs; D007082:Ileum / Q000187:drug effects; D066298:In Vitro Techniques; D009021:Morphine Dependence / Q000503:physiopathology*; D009130:Muscle, Smooth / Q000187:drug effects*; D009543:Nifedipine / Q000494:pharmacology*; D013375:Substance Withdrawal Syndrome / Q000503:physiopathology*
D009543:Nifedipine; D003000:Clonidine