Serum proteins of rats exposed to organic solvents examined by horizontal two-dimensional electrophoresis with an immobilized pH gradient in the first dimension.
Serum proteins of rats, exposed to methoxyethylacetate and a combination of methoxyethylacetate and isobutylacetate, were analyzed by horizontal high resolution two-dimensional gel electrophoresis with immobilized pH gradients in the first dimension. A total of 410 polypeptides were detected with either increasing or decreasing spot intensities after rat exposure to the organic solvents.
Zastrow
G
G
Universität Bremen, Federal Republic of Germany.
Günther
S
S
Postel
W
W
Görg
A
A
Diehl
H A
HA
Jansen
E H
EH
D000085:Acetates; D000818:Animals; D001798:Blood Proteins / Q000378:metabolism*; D015180:Electrophoresis, Gel, Two-Dimensional; D005026:Ethylene Glycols; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012997:Solvents
D000085:Acetates; D001798:Blood Proteins; D005026:Ethylene Glycols; D012997:Solvents; C038989:isobutyl acetate; C045156:2-methoxyethanol acetate