[Pharmacological studies on dingchuanning].
Dingchuanning has been found to increase markedly the perfusion of isolated lung of guinea-pig. It may produce a relaxing effect on the smooth muscles of the isolated trachea, bronchus and lung strips of guinea-pigs, as well as a prominent protective effect on the bronchial asthma induced by inhalation of bronchoconstrictors in conscious guinea-pigs. It also has significant expectorant and antianaphylactic effects and helps to inhibit markedly the SRS-A release from lung tissues and to counteract directly the activity of SRS-A.
Huang
J
J
Jiangxi College of Traditional Chinese Medicine, Nanchang.
Xu
P
P
Zhang
Z
Z
D000818:Animals; D001249:Asthma / Q000188:drug therapy; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D005100:Expectorants; D005260:Female; D006168:Guinea Pigs; D000860:Hypoxia / Q000188:drug therapy; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D009119:Muscle Contraction / Q000187:drug effects*; D009130:Muscle, Smooth / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D013189:SRS-A / Q000378:metabolism; D014132:Trachea / Q000187:drug effects
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D005100:Expectorants; D013189:SRS-A