title: [Intraluminal thrombosis and growth-mechanism of giant intracranial aneurysms].
abstract: 12 giant intracranial aneurysms were studied by MRI. Intraluminal thrombosis was observed in 9 aneurysms. Thrombosis was found more frequently in larger aneurysms. Thrombi were formed posteriorly or inferiorly in the lumen of 4 among 5 IC-cavernous aneurysms. Location of the neck of the aneurysms and stagnation of blood flow influenced by gravity may be causative factors determining the location of thrombi. In 6 aneurysms intraluminal thrombi were inhomogeneous on MRI, suggesting that the thrombi had been formed at different times. New thrombi were formed between the aneurysmal wall and the old thrombus in 3 cases. Dissection of the aneurysmal wall by residual blood flow in the lumen or hemorrhage in the aneurysmal wall may be one of the growth mechanisms of giant intracranial aneurysms.
authors.affiliation: Department of Neurosurgery, Kyoto University Medical School.
authors.forename: I
authors.initials: I
authors.lastname: Nagata
authors.forename: H
authors.initials: H
authors.lastname: Kikuchi
authors.forename: S
authors.initials: S
authors.lastname: Yamagata
authors.forename: S
authors.initials: S
authors.lastname: Miyamoto
authors.forename: T
authors.initials: T
authors.lastname: Kaneko
authors.forename: R
authors.initials: R
authors.lastname: Asato
mesh_terms: D000293:Adolescent; D000368:Aged; D001921:Brain / Q000473:pathology; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000175:diagnosis* / Q000473:pathology; D002542:Intracranial Embolism and Thrombosis / Q000150:complications* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged