title: Oral lichen planus: the clinical, historical, and therapeutic features of 100 cases.
abstract: Lichen planus is a chronic inflammatory epidermal and mucosal disease, the cause of which is poorly understood. We reviewed the clinical and historic features of 100 patients referred to our clinic for diagnosis and management of lichen planus. The age, gender, chief complaint, duration of the chief complaint, medical history, medications, and clinical findings were recorded. Past therapeutic modalities were reviewed. Of therapeutic significance, 25 patients with oral lichen planus had a secondary oral candidiasis. Management of symptomatic lichen planus with topical and systemic steroid is discussed. The pharmacology of topical and systemic steroid usage and the rationale for treatment are discussed.
authors.affiliation: Department of Oral Pathology and Diagnosis, University of Iowa College of Dentistry, Iowa City.
authors.forename: S D
authors.initials: SD
authors.lastname: Vincent
authors.forename: P G
authors.initials: PG
authors.lastname: Fotos
authors.forename: K A
authors.initials: KA
authors.lastname: Baker
authors.forename: T P
authors.initials: TP
authors.lastname: Williams
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005882:Gingival Diseases / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008010:Lichen Planus / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000188:drug therapy* / Q000473:pathology; D009067:Mouthwashes; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use; D014060:Tongue Diseases / Q000188:drug therapy / Q000473:pathology; D014222:Triamcinolone Acetonide / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D009067:Mouthwashes; D014222:Triamcinolone Acetonide; D011241:Prednisone