title: A brief technical communication: detection of fentanyl in urine.
abstract: A reliable and sensitive method to analyze fentanyl in urine was developed using radioimmunoassay (RIA). Fentanyl, a highly lipophilic drug (pKa 7.7), has become a common drug of abuse. We evaluated three analytical techniques to detect fentanyl in urine. This paper reports the best of the three - a modified solvent extraction combined with a fentanyl RIA.
authors.affiliation: Department of Anesthesiology, Children's Hospital of Pittsburgh, PA 15213-2583.
authors.forename: R L
authors.initials: RL
authors.lastname: Stiller
authors.forename: A M
authors.initials: AM
authors.lastname: Scierka
authors.forename: P J
authors.initials: PJ
authors.lastname: Davis
authors.forename: D R
authors.initials: DR
authors.lastname: Cook
mesh_terms: D005283:Fentanyl / Q000652:urine*; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D011863:Radioimmunoassay; D015203:Reproducibility of Results; D019966:Substance-Related Disorders / Q000175:diagnosis*
chemical_list: D005283:Fentanyl