Transformation of refractory anemia with excess of blasts into acute myelogenous leukemia with Ph-negative chronic myelogenous leukemia-like characteristics.
We report a 56 year old patient with acute myelogenous leukemia (FAB classification: M2), in whom the number of mature myeloid cells similar to those seen in Ph-negative chronic myelogenous leukemia increased markedly 2 months after the diagnosis of refractory anemia with excess of blasts (RAEB). This is a rare case of leukemic evolution as a terminal event of RAEB.
Yamauchi
K
K
Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.
Arimori
S
S
Nagao
T
T
D000754:Anemia, Refractory, with Excess of Blasts / Q000150:complications*; D002871:Chromosome Banding; D002882:Chromosomes, Human, Pair 13; D002895:Chromosomes, Human, Pair 5; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics; D054438:Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative / Q000209:etiology* / Q000235:genetics; D008297:Male; D008875:Middle Aged; D014178:Translocation, Genetic