[The late results of treating membranous glomerulonephritis].
27 patients with membranous glomerulonephritis treated with corticosteroids, anticoagulants and some with immunosuppressors are discussed. Men prevailed. Nephrotic syndrome proved by renal biopsy was found in 88.9%, proteinuria under 3.5 g/24 h--in 11.1%, arterial hypertension--in 18.5%, renal failure--in 14.8% of the patients. At the end of the follow up 15 patients (55.6%) showed a complete remission and 4 patients a partial remission. In 8 patients (29.6%) there was chronic renal failure and three of them had gone through hemodialysis. Comparing the patients with and without chronic renal failure we found that only the presence of impaired renal function as found by renal biopsy and the greated duration of the disease are of statistically significant importance for the prognosis of membranous glomerulonephritis. A 5 year survival of the patients treated actively is 100% and a 10 year survival is 94.9% which allows the assumption that treatment of membranous glomerulonephritis can lead to a permanent remission and preservation of renal function.
Belovezhdov
N
N
Robeva
R
R
Dimitrova
V
V
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000925:Anticoagulants / Q000627:therapeutic use; D002908:Chronic Disease; D003404:Creatinine / Q000097:blood; D004359:Drug Therapy, Combination; D005260:Female; D015433:Glomerulonephritis, Membranous / Q000097:blood / Q000150:complications / Q000188:drug therapy* / Q000401:mortality; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000209:etiology; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007676:Kidney Failure, Chronic / Q000188:drug therapy / Q000209:etiology; D008297:Male; D009404:Nephrotic Syndrome / Q000188:drug therapy / Q000209:etiology; D011507:Proteinuria / Q000188:drug therapy / Q000209:etiology
D000305:Adrenal Cortex Hormones; D000925:Anticoagulants; D007166:Immunosuppressive Agents; D003404:Creatinine
Kŭsni rezultati ot lechenieto na membranozniia glomerulonefrit.