[Effect of prostaglandins E2 and F2alpha on hemodynamics during adrenoreceptor activation in dogs with the limb reperfusion syndrome].
Experiments were conducted on 47 mongrel dogs with the limb reperfusion syndrome (RS) to study the effect of prostaglandins (PG) E2 and F2 alpha on changes of hemodynamics and some values of adrenergic reaction induced by norepinephrine injection. Increase of the adrenergic reaction in the limb RS was found to be directly dependent on the duration of the syndrome. PG E2 intensified still more the norepinephrine effect on hemodynamics, while F2 alpha, in contrast, weakened the adrenergic reaction in the limb RS.
Abaskulieva
L I
LI
Mekhtieva
A A
AA
D000818:Animals; D015237:Dinoprost / Q000494:pharmacology*; D015232:Dinoprostone / Q000494:pharmacology*; D004285:Dogs; D005121:Extremities / Q000098:blood supply*; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D008297:Male; D011941:Receptors, Adrenergic / Q000187:drug effects*; D015427:Reperfusion Injury / Q000503:physiopathology*; D013577:Syndrome
D011941:Receptors, Adrenergic; D015237:Dinoprost; D015232:Dinoprostone
Vliianie prostaglandinov E2 i F2alpha na gemodinamiku na fone aktivatsii adrenoretseptorov u sobak s sindromom reperfuzii konechnosti.