title: i(12p) in a malignant ovarian tumor.
abstract: We have found one or more copies of i(12p) in an ovarian germ cell tumor, histologically a yolk sac tumor. This chromosome marker is characteristically associated with germ cell tumors in males. This report indicates that further investigation is necessary to establish the role of the i(12p) marker in the pathogenesis of germ cell tumors also in females.
authors.affiliation: Department of Medical Genetics, University Hospital Gent, Belgium.
authors.forename: F
authors.initials: F
authors.lastname: Speleman
authors.forename: C
authors.initials: C
authors.lastname: De Potter
authors.forename: P
authors.initials: P
authors.lastname: Dal Cin
authors.forename: K
authors.initials: K
authors.lastname: Mangelschots
authors.forename: H
authors.initials: H
authors.lastname: Ingelaere
authors.forename: G
authors.initials: G
authors.lastname: Laureys
authors.forename: Y
authors.initials: Y
authors.lastname: Benoit
authors.forename: J
authors.initials: J
authors.lastname: Leroy
authors.forename: H
authors.initials: H
authors.lastname: Van Den Berghe
mesh_terms: D002675:Child, Preschool; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002881:Chromosomes, Human, Pair 12; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D008649:Mesonephroma / Q000235:genetics* / Q000473:pathology; D010051:Ovarian Neoplasms / Q000235:genetics* / Q000473:pathology
chemical_list: D005819:Genetic Markers