title: Aldrin toxicity on amphibian neuronal, hepatic and muscular tissue oxidative enzymes.
abstract: Aldrin toxicity was studied in the brain, liver and muscle of Rana hexadactyla. It was observed that sublethal concentration of aldrin inhibited the activities of SDH, MDH and ICDH while it elevated the activities of LDH and G-6-PDH. The increase and the decrease was progressive with the exposure period. The changes were attributed to the induced toxic effects such as oxygen distress, energy crisis and microstructural changes.
authors.affiliation: Department of Zoology, Sri Venkateswara University, Tirupati, India.
authors.forename: K V
authors.initials: KV
authors.lastname: Joseph
authors.forename: K J
authors.initials: KJ
authors.lastname: Rao
mesh_terms: D000452:Aldrin / Q000633:toxicity*; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000201:enzymology*; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D007521:Isocitrate Dehydrogenase / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008291:Malate Dehydrogenase / Q000378:metabolism; D009132:Muscles / Q000187:drug effects / Q000201:enzymology*; D010084:Oxidation-Reduction; D011898:Ranidae; D013385:Succinate Dehydrogenase / Q000378:metabolism
chemical_list: D007770:L-Lactate Dehydrogenase; D008291:Malate Dehydrogenase; D007521:Isocitrate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D013385:Succinate Dehydrogenase; D000452:Aldrin