title: Plaque formation of dietary isomaltulose in humans.
abstract: The plaque formation of isomaltulose, a sucrose isomer, was examined in 15 human volunteers with both diet and oral hygiene under supervision. The subjects were requested to refrain from all oral hygiene procedures for 3 days and were provided between-meal snacks containing 157 g of 4 test sugars (100% isomaltulose, 70% isomaltulose + 30% sucrose, 50% isomaltulose + 50% sucrose, and 100% sucrose). The study was repeated 4 times over 4 weeks. The isomaltulose diet resulted in the lowest plaque index, while sucrose induced a significantly greater deposition. In the absence of sucrose-containing snacks, mutans streptococci in saliva decreased below the baseline level. These results suggest that isomaltulose may be a suitable substitute for sucrose in between meal snacks.
authors.affiliation: Department of Pedodontics, Osaka University Faculty of Dentistry, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ooshima
authors.forename: A
authors.initials: A
authors.lastname: Izumitani
authors.forename: T
authors.initials: T
authors.lastname: Takei
authors.forename: T
authors.initials: T
authors.lastname: Fujiwara
authors.forename: S
authors.initials: S
authors.lastname: Sobue
mesh_terms: D000328:Adult; D003773:Dental Plaque / Q000209:etiology* / Q000378:metabolism; D003774:Dental Plaque Index; D004040:Dietary Carbohydrates / Q000008:administration & dosage / Q000378:metabolism; D004187:Disaccharides / Q000378:metabolism*; D006801:Humans; D007534:Isomaltose / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D012463:Saliva / Q000382:microbiology*; D013295:Streptococcus mutans / Q000302:isolation & purification*; D013395:Sucrose / Q000008:administration & dosage / Q000378:metabolism*
chemical_list: D004040:Dietary Carbohydrates; D004187:Disaccharides; D013395:Sucrose; D007534:Isomaltose; C008189:isomaltulose