Ga-labeling of immunoglobulin G with high specific radioactivity.
To obtain radiogallium labeled immunoglobulin G with a high specific radioactivity for in vitro use, a 67Ga source was purified by extraction from 67Ga-gallium citrate with butyl acetate, and a 67Ga-labeling solution was produced. This solution was then used to label a deferoxamine-immunoglobulin G conjugate. Both a very high specific radioactivity (872 +/- 56 MBq/mg) and a high labeling efficiency (94.0%) were achieved.
Furukawa
T
T
Department of Health Chemistry, Kansai Medical University, Osaka, Japan.
Fujibayashi
Y
Y
Fukunaga
M
M
Yokoyama
A
A
D005710:Gallium Radioisotopes; D007074:Immunoglobulin G; D007553:Isotope Labeling; D011863:Radioimmunoassay
D005710:Gallium Radioisotopes; D007074:Immunoglobulin G