Unusual presentation of paraproteinemic corneal infiltrates.
A 76-year-old man with bilateral corneal infiltrates secondary to a monoclonal gammopathy of undetermined significance (MGUS) is described. The corneal changes simulated a remote lattice dystrophy. Although the clinical presentation of corneal opacities secondary to paraproteinemic conditions is somewhat variable, this patient's corneas lacked the common crystalline appearance of immunoglobulin deposits. This patient demonstrates an atypical clinical presentation of corneal infiltration secondary to a paraproteinemia.
Spiegel
P
P
Department of Pathology, University Hospitals of Cleveland, Case Western Reserve University, Ohio.
Grossniklaus
H E
HE
Reinhart
W J
WJ
Thomas
R H
RH
D000368:Aged; D001797:Blood Protein Electrophoresis; D003315:Cornea / Q000648:ultrastructure; D003316:Corneal Diseases / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007122:Immunoelectrophoresis; D007136:Immunoglobulins / Q000378:metabolism; D015948:Keratoplasty, Penetrating; D007910:Lenses, Intraocular; D008297:Male; D010265:Paraproteinemias / Q000150:complications*; D014792:Visual Acuity
D007136:Immunoglobulins