title: Improved cancer chemotherapy. Benefits of delivery by infusion.
abstract: Chemotherapy delivered by infusion has developed in the last decade, primarily as a consequence of advances in technology but perhaps also because of increasing scientific understanding of pharmacology and tumor cell kinetics. Although few prospective, randomized trials have compared infusion-delivery with bolus-delivery schedules, those that have been performed have found that the infusion schedule provides at least a comparable response rate while improving drug toxicity.
authors.affiliation: Cancer Center, Boston.
authors.forename: J J
authors.initials: JJ
authors.lastname: Lokich
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D006801:Humans; D007262:Infusions, Intravenous; D007275:Injections, Intravenous; D009369:Neoplasms / Q000188:drug therapy*