The clinical significance of microalbuminuria in diabetes mellitus.
Diabetic nephropathy is the major cause of death in patients with type I diabetes mellitus and accounts for one forth of all patients with end stage renal disease. Once the renal disease becomes established, glycemic control does not significantly delay its progression. Microalbuminuria has been shown to be an early marker for the subsequent development of diabetic nephropathy. Recent evidence suggests that intensive therapy started during this subclinical phase might delay the progression of diabetic nephropathy to renal failure. Methods for measuring microalbuminuria are now commercially available.
Nagoshi
M H
MH
University of Hawaii, Dept. of Medicine, Queen Emma Clinics, Honolulu.
Miyahira
W Y
WY
D000419:Albuminuria / Q000652:urine*; D003920:Diabetes Mellitus / Q000652:urine*; D003928:Diabetic Nephropathies / Q000652:urine; D006801:Humans