title: Postarthroscopy analgesia with bupivacaine. A prospective, randomized, blinded evaluation.
abstract: The analgesic effect of intraarticular bupivacaine injected at the conclusion of knee arthroscopy done under general anesthesia was investigated in a prospective, randomized, and blinded fashion. Pain scores, the use of analgesic medications, crutch use, weight-bearing, activity level, and difficulty sleeping the night after surgery were all unaffected by the use of bupivacaine. The apparent lack of effect is most likely due to rapid clearance from the knee, leaving only a transient, 1 to 2 hours of potential benefit. In this study, the patients were already quite comfortable during this time period due to the routine use of intraoperative narcotics. The preoperative level of knee discomfort was found to be a major determinant of postoperative discomfort. Other much less important factors were synovial and chondral shaving, sex of the patient, and experience of the surgeon.
authors.affiliation: Division of Orthopaedics, University of North Carolina, Chapel Hill 27599.
authors.forename: R C
authors.initials: RC
authors.lastname: Henderson
authors.forename: E R
authors.initials: ER
authors.lastname: Campion
authors.forename: R A
authors.initials: RA
authors.lastname: DeMasi
authors.forename: T N
authors.initials: TN
authors.lastname: Taft
mesh_terms: D000328:Adult; D001182:Arthroscopy; D002045:Bupivacaine / Q000008:administration & dosage*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007592:Joint Diseases / Q000175:diagnosis / Q000601:surgery; D007719:Knee Joint / Q000601:surgery*; D008297:Male; D010149:Postoperative Pain / Q000517:prevention & control*; D011446:Prospective Studies; D011795:Surveys and Questionnaires
chemical_list: D002045:Bupivacaine