title: Antistaphylococcal activity of pentamidine.
abstract: Pentamidine isethionate was bacteriostatic against Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, Streptococcus sanguis, Micrococcus sp., and Candida albicans. S. aureus was inhibited by concentrations of 16 to 64 micrograms/ml and killed by 64 to greater than or equal to 128 micrograms/ml. Staphylococcal killing was consistently greater in the presence of cations and was unaffected by methicillin resistance.
authors.affiliation: McGill University, Montreal General Hospital, Quebec, Canada.
authors.forename: M D
authors.initials: MD
authors.lastname: Libman
authors.forename: M A
authors.initials: MA
authors.lastname: Miller
authors.forename: G K
authors.initials: GK
authors.lastname: Richards
mesh_terms: D006801:Humans; D008826:Microbial Sensitivity Tests; D010419:Pentamidine / Q000494:pharmacology*; D013210:Staphylococcus / Q000187:drug effects*; D013211:Staphylococcus aureus / Q000187:drug effects; D013212:Staphylococcus epidermidis / Q000187:drug effects
chemical_list: D010419:Pentamidine