Cytogenetics of thyroid follicular adenomas.
We present the results of a cytogenetic study of three cases of follicular adenoma of the thyroid. All three cases had a numerical strongly abnormal karyotype with most abnormalities (eg, +4 or +5, +7, +9, +12, +16) in common, possibly indicating that this cluster of abnormalities might be specific for follicular adenomas. For benign tumors, the three cases showed a remarkably abnormal karyotype. These cases are another example of benign tumors with chromosomal abnormalities that might be specific for follicular adenomas.
van den Berg
E
E
Department of Pathology, State University of Groningen, The Netherlands.
Oosterhuis
J W
JW
de Jong
B
B
Buist
J
J
Vos
A
A
Dam
A
A
Vermeij
B
B
D000236:Adenoma / Q000235:genetics* / Q000473:pathology; D000328:Adult; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000235:genetics* / Q000473:pathology