title: [Treatment of condyloma acuminata using human lymphoblastoid interferon].
abstract: Eighteen cases of condyloma acuminata were treated by human lymphoblastoid interferon (HLBI). Seventeen were male and one was female. Five cases were recurrent cases. Except one patient, all the patients were administered HLBI by intralesional injection. Five patients were treated by single injection. Others were given 2 to 8 injections during one to 5 weeks. Total dose varied from 3 x 10(6) to 24 x 10(6) U. Of the eighteen patients, 6 showed a complete response and 3 a partial response (greater than 50% reduction in size of the lesion). In 5 of the 11 patients (45%) who were treated with a total dosage of more than 12 x 10(6) U, the lesion was completely cleared. Six patients who showed a complete response did not experience recurrent disease during the 6-month follow-up period. In conclusion, intralesional administration of HLBI for condyloma acuminata proved to be effective.
authors.affiliation: Department of Urology, Okazaki City Hospital.
authors.forename: T
authors.initials: T
authors.lastname: Kinukawa
authors.forename: R
authors.initials: R
authors.lastname: Hattori
authors.forename: T
authors.initials: T
authors.lastname: Furukawa
authors.forename: S
authors.initials: S
authors.lastname: Ohshima
authors.forename: O
authors.initials: O
authors.lastname: Matsuura
authors.forename: N
authors.initials: N
authors.lastname: Takeuchi
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: J
authors.initials: J
authors.lastname: Hashimoto
authors.forename: Y
authors.initials: Y
authors.lastname: Ono
authors.forename: J
authors.initials: J
authors.lastname: Watanabe
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003218:Condylomata Acuminata / Q000628:therapy*; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D007370:Interferon Type I / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D010412:Penile Neoplasms / Q000628:therapy*; D012008:Recurrence; D014846:Vulvar Neoplasms / Q000628:therapy*
chemical_list: D007370:Interferon Type I