title: The effect of ethanol on stress-induced tachycardia.
abstract: A study was designed to answer the questions if low doses of ethanol would reduce stress induced increases in heart rates, if covariations would be observed between ethanol induced changes in heart rates and changes in emotional states and mental performance and if tolerance to ethanol or other personality factors would influence the ethanol induced cardiac effects. Forty-four male students with a history of high and low alcohol consumption according to questionnaire scores were matched for extraversion and neuroticism and then assigned to a group receiving either 0.8 g/kg of ethanol or a placebo drink. A stress condition of mental arithmetic was applied prior to and 45 minutes after ingestion of the drink. Heart rates and ratings of emotional states by adjective check lists were recorded before and after each stress session. A significant reduction of stress induced heart rate increases in both high and low drinking groups but no ethanol dependent change of resting heart rates were observed. Reductions of autonomic stress response by ethanol were weakly but positively correlated to respective reductions of affective stress responses and impairment of the quality of mental performance. High trait anxiety subjects seemed to benefit more from ethanol with respect to reductions of cardiac and emotional arousal than low anxious subjects.
authors.affiliation: Department of Pharmacology and Psychiatry and Human Behavior, Thomas Jefferson University, Philadelphia, PA 19107.
authors.forename: W H
authors.initials: WH
authors.lastname: Vogel
authors.forename: P
authors.initials: P
authors.lastname: Netter
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000503:physiopathology / Q000523:psychology*; D001143:Arousal / Q000187:drug effects* / Q000502:physiology; D004562:Electrocardiography / Q000187:drug effects*; D004644:Emotions / Q000502:physiology; D006339:Heart Rate / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D008297:Male; D010556:Personality Tests; D013315:Stress, Psychological / Q000150:complications*