Incidence of visual cortical neurons which have axon collaterals projecting to both cerebral hemispheres during prenatal primate development.
Fast blue was injected massively in extrastriate cortex of one hemisphere Diamidino yellow in area 17 of the other hemisphere, in adult and prenatal cynomolgus monkeys. After a suitable survival period the brains were processed for fluorescent dyes. Counts were made of the total number of labeled neurons and of those neurons which were labeled by both dyes and which project therefore to both hemispheres by means of bifurcating axon collaterals. At 122 and 135 days after conception (E122 and E135), shortly after cortico-cortical pathways are established, double-labeled neurons constituted 0.45% and 0.46% of the total population of labeled neurons in area V2. In V2 in the adult the range of values of double-labeled neurons was 0.03-0.08%.
Meissirel
C
C
Vision et Motricité, INSERM U94, Bron, France.
Dehay
C
C
Berland
M
M
Kennedy
H
H
D000818:Animals; D001369:Axons / Q000648:ultrastructure; D002452:Cell Count; D002540:Cerebral Cortex / Q000196:embryology* / Q000254:growth & development / Q000648:ultrastructure; D005314:Embryonic and Fetal Development / Q000502:physiology; D005260:Female; D008252:Macaca fascicularis / Q000196:embryology; D009434:Neural Pathways / Q000196:embryology / Q000254:growth & development / Q000648:ultrastructure; D009474:Neurons / Q000648:ultrastructure*; D014793:Visual Cortex / Q000166:cytology / Q000196:embryology* / Q000254:growth & development