title: [Increase of the negative charge of erythrocyte membrane proteins in hereditary neuromuscular diseases].
abstract: The parameters of erythrocyte ghost protein's fluorophores by nitrate's anions were studied in patients with various hereditary myodystrophy. In all the groups under examination the share of fluorophores accessible to a quencher was close to 1. In erythrocyte membranes of healthy donors the relevant constant quenchering was about 17.3 +/- 1.9 M-1 while those of patients were decreased by 3.1 (Duchenne's myodystrophy) and by about 2.0 (other forms of primary and secondary progressive muscular dystrophies). The most probable reason for the decreasing constant of quenchering is the increase of negative charges on the erythrocyte membrane proteins.
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Khrennikov
authors.forename: A I
authors.initials: AI
authors.lastname: Deev
authors.forename: V F
authors.initials: VF
authors.lastname: Sitnikov
authors.forename: A F
authors.initials: AF
authors.lastname: Tagiev
mesh_terms: D004910:Erythrocyte Membrane / Q000737:chemistry*; D006801:Humans; D008565:Membrane Proteins / Q000032:analysis*; D008954:Models, Biological; D009468:Neuromuscular Diseases / Q000235:genetics / Q000378:metabolism*; D013050:Spectrometry, Fluorescence; D013053:Spectrophotometry
chemical_list: D008565:Membrane Proteins
vernacular_title: Uvelichenie otritsatel'nogo zariada belkov membrany éritrotsitov pri nasledstvennykh nervno-myshechnykh zabolevaniiakh.