title: Chemical studies on Mexican plants used in traditional medicine, XV. Sesquiterpene evoninoate alkaloids from Hippocratea excelsa.
abstract: Three sesquiterpene evoninoate alkaloids, hippocrateine I [1], hippocrateine II [2], and emarginatine A have been isolated from the root and stem barks of Hippocratea excelsa. Compounds 1 and 2 are new naturally occurring substances. The structure of 1 was unequivocally established by X-ray crystallographic analysis, and the structure of the second new alkaloid was deduced by spectral analysis.
authors.affiliation: División de Bioquímica y Farmacia, Facultad de Química, Ciudad Universitaria, México D.F.
authors.forename: R
authors.initials: R
authors.lastname: Mata
authors.forename: F
authors.initials: F
authors.lastname: Calzada
authors.forename: E
authors.initials: E
authors.lastname: Díaz
authors.forename: R A
authors.initials: RA
authors.lastname: Toscano
mesh_terms: D000470:Alkaloids / Q000302:isolation & purification* / Q000494:pharmacology; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification*; D001156:Artemia / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D009682:Magnetic Resonance Spectroscopy; D008519:Medicine, Traditional; D008800:Mexico; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000032:analysis*; D012717:Sesquiterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured / Q000187:drug effects
chemical_list: D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D012717:Sesquiterpenes; C064682:emarginatine A; C067646:hippocrateine I; C067647:hippocrateine II