title: Pediatric urological complications with intraoperative radiation therapy.
abstract: Intraoperative radiotherapy with variable energy electrons has been used as a supplemental boost to treat 6 children with locally advanced retroperitoneal malignancies. Of the patients 4 had treatment-related injuries to portions of the urinary tract within the intraoperative and external radiation fields. Three patients had significant renal impairment requiring surgical correction. The pathogenesis and management of treatment-induced injury to the urinary tract are discussed.
authors.affiliation: Department of Urology, Mayo Clinic, Rochester, Minnesota 55905.
authors.forename: M L
authors.initials: ML
authors.lastname: Ritchey
authors.forename: L L
authors.initials: LL
authors.lastname: Gunderson
authors.forename: W A
authors.initials: WA
authors.lastname: Smithson
authors.forename: P P
authors.initials: PP
authors.lastname: Kelalis
authors.forename: B H
authors.initials: BH
authors.lastname: Kaufman
authors.forename: R L
authors.initials: RL
authors.lastname: Telander
authors.forename: R G
authors.initials: RG
authors.lastname: Evans
authors.forename: S A
authors.initials: SA
authors.lastname: Kramer
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D007674:Kidney Diseases / Q000209:etiology* / Q000473:pathology; D008297:Male; D011832:Radiation Injuries / Q000473:pathology*; D011878:Radiotherapy / Q000009:adverse effects; D012186:Retroperitoneal Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D014515:Ureteral Diseases / Q000209:etiology* / Q000473:pathology