Polymorphism of a platelet polypeptide.
Polymorphism of a platelet protein is described. The gene products are represented by two peptides of MW around 30 kD. The allele frequency was estimated to 0.85 and 0.15, the common variant being of slightly higher MW and about 2 charge units more acidic than the other. The peptides were neither released nor phosphorylated, and subcelluar fractionation indicated localization to the cytosol. Attempts to raise antibodies failed, and further characterization could not be done, but the peptides seem to differ from all reasonably well characterized platelet proteins so far.
Stormorken
H
H
Research Institute of Internal Medicine, Medical Dept A, Oslo, Norway.
Hellum
B
B
Nakstad
B
B
Thorsrud
A K
AK
Jellum
E
E
D000483:Alleles; D001792:Blood Platelets / Q000737:chemistry*; D003600:Cytosol / Q000737:chemistry; D005787:Gene Frequency; D006801:Humans; D007526:Isoelectric Point; D008970:Molecular Weight; D010455:Peptides / Q000097:blood* / Q000737:chemistry / Q000235:genetics; D011110:Polymorphism, Genetic
D010455:Peptides