title: Prospective study utilizing transdermal scopolamine in detrusor instability.
abstract: Ten patients with pure detrusor instability were treated in a prospective fashion with transdermal scopolamine. Seventy percent of patients experienced moderate to severe untoward symptoms requiring discontinuation of medication. Three of 10 patients (30%) demonstrated a subjective improvement although only 1 was able to tolerate the medication. No objective change in detrusor instability was demonstrated.
authors.affiliation: Department of Obstetrics and Gynecology, University of California, Irvine.
authors.forename: J L
authors.initials: JL
authors.lastname: Cornella
authors.forename: A E
authors.initials: AE
authors.lastname: Bent
authors.forename: D R
authors.initials: DR
authors.lastname: Ostergard
authors.forename: N S
authors.initials: NS
authors.lastname: Horbach
mesh_terms: D000279:Administration, Cutaneous; D006801:Humans; D010865:Pilot Projects; D011446:Prospective Studies; D012601:Scopolamine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001750:Urinary Bladder, Neurogenic / Q000188:drug therapy*
chemical_list: D012601:Scopolamine