A brief technical communication: detection of fentanyl in urine.
A reliable and sensitive method to analyze fentanyl in urine was developed using radioimmunoassay (RIA). Fentanyl, a highly lipophilic drug (pKa 7.7), has become a common drug of abuse. We evaluated three analytical techniques to detect fentanyl in urine. This paper reports the best of the three - a modified solvent extraction combined with a fentanyl RIA.
Stiller
R L
RL
Department of Anesthesiology, Children's Hospital of Pittsburgh, PA 15213-2583.
Scierka
A M
AM
Davis
P J
PJ
Cook
D R
DR
D005283:Fentanyl / Q000652:urine*; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D011863:Radioimmunoassay; D015203:Reproducibility of Results; D019966:Substance-Related Disorders / Q000175:diagnosis*
D005283:Fentanyl