Formulas predicting the percentile of heart weights by body weight in subjects from birth to 19 years of age.
The values reported by Scholz and his coworkers [Mayo Clin Proc, 63 (1988) 126-136,637] show that distributions of normal heart weights in the period of body growth from birth to 19 years of age are age and sex dependent and actually more dependent on body weight. General formulas are constructed on the basis of the values of Scholz and his coworkers to predict percentile in the population for heart weights by body weight. A mathematical model and a computer program previously published by the author are employed in this study. Analysis of the computer-assisted predicted values and the data on heart weights for specific body weights and percentiles reported by Scholz and his coworkers indicates that the designed computer program for calculating the formula is accurate and reliable. The formulas can determine the mathematical relationship among body weight, heart weight and population percentile. It seems to the author that the computer-assisted predictive formula has limited values in its clinical application since heart weights are to be evaluated practically only in autopsy service in pathology, but that a similar mathematical model as used in this study would be applicable in analysis of other clinical, age- and sex-dependent measurable parameters.
Chung
S J
SJ
Department of Pathology, Morristown-Hamblen Hospital, TN 37814.
D000328:Adult; D000367:Age Factors; D001835:Body Weight / Q000502:physiology*; D005260:Female; D006321:Heart / Q000033:anatomy & histology / Q000254:growth & development*; D006801:Humans; D008297:Male; D008432:Mathematical Computing; D008838:Microcomputers; D008954:Models, Biological; D009929:Organ Size / Q000502:physiology; D012985:Software Design