title: Activities of serum cathepsin (B, H and L) and metalloproteinase (MMP7-ase) in patients with gastrointestinal and bronchial malignant tumours.
abstract: Serum lysosomal cysteine proteinases cathepsin B, H, L and metalloproteinase (MMP7-ase) activities of 14 patients suffering from gastrointestinal and bronchial carcinomas were investigated. The serum cathepsin B and H activities were significantly diminished in the carcinoma group as compared to the controls, while the activity of cathepsin L and of MMP7-ase was normal.
authors.affiliation: Pediatric Department, Albert Szent-Györgyi University Medical School, Szeged.
authors.forename: A
authors.initials: A
authors.lastname: László
authors.forename: I
authors.initials: I
authors.lastname: Sohár
authors.forename: S
authors.initials: S
authors.lastname: Karácsonyi
authors.forename: A
authors.initials: A
authors.lastname: Petri
authors.forename: I
authors.initials: I
authors.lastname: Troján
mesh_terms: D002401:Cathepsin B / Q000097:blood; D056655:Cathepsin H; D056668:Cathepsin L; D002403:Cathepsins / Q000097:blood*; D003546:Cysteine Endopeptidases; D010450:Endopeptidases; D005770:Gastrointestinal Neoplasms / Q000097:blood / Q000201:enzymology*; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood / Q000201:enzymology*; D008247:Lysosomes / Q000201:enzymology; D008666:Metalloendopeptidases / Q000097:blood*; D012016:Reference Values
chemical_list: D002403:Cathepsins; D010450:Endopeptidases; D003546:Cysteine Endopeptidases; D002401:Cathepsin B; C534281:CTSL protein, human; D056668:Cathepsin L; C534126:CTSH protein, human; D056655:Cathepsin H; D008666:Metalloendopeptidases