[The Lupus Band Test and serology of lupus erythematosus. Our experience].
The Authors studied, from 1986 to 1988, 84 patients (24 men and 60 women, in an age group that went from 13 to 75 years, with an average of 42 years) in whom DLE was diagnosed. In these patients, a direct immunofluorescent assay was carried out on the affected skin, on the non-affected photoexposed skin, and on the non-affected non-photoexposed skin: furthermore, the serum of these patients was tested for the presence of antinuclear antibodies (ANA), antibodies to extractable nuclear antigens (anti-ENA), and antibodies to double-stranded DNA (anti-DNA). In the study, a significant correlation between the presence of ANA and entity of cutaneous involvement at the Lupus Band Test was found. Furthermore, it was noticed that anti-ENA and/or anti-nDNA tend to be present in association to a positive Lupus Band Test in all 3 biopsied tissues.
Varotti
C
C
Istituto di Clinica Dermatologica, Università di Bologna.
Patrizi
A
A
Siverio
G A
GA
Masina
M
M
Passarini
B
B
D000293:Adolescent; D000328:Adult; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012698:Serologic Tests
Lupus Band Test e sierologia nel lupus eritematoso. Nostra esperienza.