Carbamazepine and the lung.
A 69 yr old man was admitted with a 10 day history of fever, arthromyalgia, dyspnoea, dry cough and pleuritic pain. Temperature was 38 degrees C; tachypnoea 36 rpm. Extensive crackles were audible over both upper lung fields. Chest X-ray showed bilateral alveolar infiltrates. Forced vital capacity was 49% of predicted, and carbon monoxide transfer coefficient was 32% of predicted value. The patient had been taking carbamazepine for one month because of a trigeminal neuralgia. After withdrawal of the drug he gradually recovered.
Barreiro
B
B
Servei de Pneumologia, Hospital de Bellvitge, University of Barcelona, Spain.
Manresa
F
F
Valldeperas
J
J
D000368:Aged; D002220:Carbamazepine / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009437:Neuralgia / Q000175:diagnosis / Q000188:drug therapy; D011014:Pneumonia / Q000139:chemically induced*
D002220:Carbamazepine