[Evaluation of effectiveness and safety and quantitative evaluation of the use of fluocinolone acetonide in cream (0.025%) and medicated tape (8 micrograms/cm2) in the treatment of psoriasis].
Eighteen male patients, mean aged of 55.7 years, affected by psoriasis were treated for an average of 19 days with fluocinolone acetonide (FA) using an occlusive traditional dressing with a 0.025% cream or with a medicated plastic porous tape (8 micrograms/cm2), according to a controlled hemipart design. The average total quantity of FA administrated for each patient was 3.431 mg on the side treated with tape and 19.827 mg on the side treated with cream. Both the treatments showed excellent efficacy (ANOVA between times p less than 0.01), better with the tape than with the occlusive conventional dressing. The patients preferred the use of the tape to the cream. The tolerability was very good. Treatment with the medicated tape was shown to be more effective than the occlusive traditional dressing, and yielded a reduction of the quantity of corticosteroid administrated to the patients.
Bedello
P
P
Clinica Dermatologica, Università degli Studi di Torino.
De Paoli
M
M
D000279:Administration, Cutaneous; D000328:Adult; D000368:Aged; D001458:Bandages; D005446:Fluocinolone Acetonide / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009824:Ointments; D011565:Psoriasis / Q000188:drug therapy*
D009824:Ointments; D005446:Fluocinolone Acetonide
Valutazione dell'efficacia e della tollerabilità e valutazione quantitativa del consumo di fluocinolone acetonide in pomata allo 0.025% e cerotto medicato (8 micrograms/cm2) nella psoriasi.