Grinspan's syndrome: a drug-induced phenomenon?
Three cases of apparently drug-induced Grinspan's syndrome involving the triad of oral lichen planus, diabetes mellitus, and hypertension are reported. Because drug therapy for diabetes mellitus and hypertension is capable of producing lichenoid reactions of the oral mucosa, the question arises as to whether Grinspan's syndrome is an iatrogenically induced syndrome.
Lamey
P J
PJ
Department of Oral Medicine and Pathology, Glasgow Dental Hospital and School, Scotland.
Gibson
J
J
Barclay
S C
SC
Miller
S
S
D000368:Aged; D000369:Aged, 80 and over; D001262:Atenolol / Q000009:adverse effects; D001539:Bendroflumethiazide / Q000009:adverse effects; D002747:Chlorpropamide; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D005665:Furosemide / Q000009:adverse effects; D005913:Glipizide / Q000009:adverse effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008010:Lichen Planus / Q000139:chemically induced* / Q000473:pathology; D008687:Metformin / Q000009:adverse effects; D008875:Middle Aged; D009059:Mouth Diseases / Q000139:chemically induced* / Q000473:pathology; D013148:Spironolactone / Q000009:adverse effects; D013577:Syndrome
D013148:Spironolactone; D001262:Atenolol; D001539:Bendroflumethiazide; D005665:Furosemide; D008687:Metformin; D002747:Chlorpropamide; D005913:Glipizide