Comparison of serum and plasma taurine values in Bengal tigers with values in taurine-sufficient and -deficient domestic cats.
A white Bengal tiger was determined to have a central retinal lesion and a central visual defect. Because of the known association between feline central retinal degeneration (CRD) and taurine deficiency in domestic cats, plasma concentrations of taurine were measured in this tiger. Serum concentrations of taurine, methionine, and cystine also were measured in white Bengal tigers, orange Bengal tigers, taurine-sufficient domestic cats, and taurine-deprived and tissue-taurine-depleted visually impaired cats with CRD. Hepatic and brain enzymes responsible for taurine synthesis were identified in tissue specimens from an orange Bengal tiger. Serum taurine concentrations were lower in white vs orange tigers, but were not as low as those in cats with CRD. Thus, we concluded that taurine depletion did not account for the central retinal lesion in the white Bengal tiger.
Pickett
J P
JP
Department of Pediatrics, School of Veterinary Medicine, University of Wisconsin, Madison 53706.
Chesney
R W
RW
Beehler
B
B
Moore
C P
CP
Lippincott
S
S
Sturman
J
J
Ketring
K L
KL
D000818:Animals; D002335:Carnivora / Q000097:blood*; D002371:Cat Diseases / Q000097:blood*; D002415:Cats / Q000097:blood*; D003553:Cystine / Q000097:blood; D005260:Female; D008297:Male; D008715:Methionine / Q000097:blood; D012016:Reference Values; D012162:Retinal Degeneration / Q000097:blood / Q000662:veterinary*; D013654:Taurine / Q000097:blood*
D013654:Taurine; D003553:Cystine; D008715:Methionine