[Severe liver involvement by Capillaria hepatica].
Human hepatic capillariasis is a rare disease, which predominantly affects children aged 1 to 4 years and has a poor prognosis in extensive infections. This is the first case observed in Germany. The main symptoms are those of severe parasitosis: persistent high fever, hepatomegaly, and excessive hypereosinophilia. Diagnosis is confirmed by the finding of intracellular typical eggs in liver biopsy. There is a lack of established therapy; our 18 months old girl developed liver fibrosis. She survived under a prolonged treatment with high doses of Thiabendazole and two single doses of Ivermectine. Decortin was given to inhibit further granulomatous processes in the liver.
Pannenbecker
J
J
Kinderklinik und Kinderpoliklinik, Universität Würzburg.
Miller
T C
TC
Müller
J
J
Jeschke
R
R
D000818:Animals; D002195:Capillaria / Q000648:ultrastructure; D003937:Diagnosis, Differential; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007223:Infant; D007559:Ivermectin / Q000008:administration & dosage; D008099:Liver / Q000473:pathology; D008109:Liver Diseases, Parasitic / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D009349:Nematode Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D013827:Thiabendazole / Q000008:administration & dosage
D007559:Ivermectin; D013827:Thiabendazole
Schwerer Leberbefall durch Capillaria hepatica.