Genetic polymorphisms of HLA class III and GLO1 in Chinese Yao nationality.
Yao is one of the minority nationalities located mainly in the South of China (Guang Xi province). The purpose of this study was to examine HLA class III and GLO1 in Yao nationality to identify the difference between Yao and Han. Han is the major nationality in China. Yao has the lowest C2*C frequency (0.9336) in the world. Before this study the lowest C2*C frequency known was that of the Japanese (0.9386). Gene frequencies in Yao are the following: C2*C = 0.9336, C2*B = 0.0664; BF*S = 0.9071, BF*F = 0.0929; C4A*4 = 0.0253, C4A*3 = 0.6061, C4A*2 = 0.2121, C4A*1 = 0.0152, C4A*Q0 = 0.1414; C4B*3 = 0.0051, C4B*2 = 0.0657, C4B*1 = 0.7071, C4B*92 = 0.0455, C4B*95 = 0.0253, C4B*96 = 0.0253, C4B*12 = 0.0051, C4B*Q0 = 0.1212; GLO1*1 = 0.1161, GLO1*2 = 0.8839. We have compared these data with those reported for Han.
Wang
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Department of Patophysiology, Tongji Medical University, Wuhan, P.R. of China.
Tian
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YW
Wu
X W
XW
Zhao
X Z
XZ
D001782:Blood Donors; D002681:China; D003175:Complement C2 / Q000235:genetics*; D003181:Complement C4 / Q000235:genetics*; D011415:Complement Factor B / Q000235:genetics*; D005006:Ethnicity; D005787:Gene Frequency; D005819:Genetic Markers; D006801:Humans; D007791:Lactoylglutathione Lyase / Q000235:genetics*; D008285:Major Histocompatibility Complex; D010641:Phenotype; D011110:Polymorphism, Genetic
D003175:Complement C2; D003181:Complement C4; D005819:Genetic Markers; D011415:Complement Factor B; D007791:Lactoylglutathione Lyase