[Immunofluorescence study of intermediate filament protein vimentin of CP-activated macrophages].
Vimentin is an important cytoskeleton protein for the biological function of macrophages. Alterations of vimentin filaments of CP-activated macrophages stained with FITC-labeled anti-vimentin antibody were observed under immunofluorescence microscope. Activated macrophages showed changes with the following characteristics: the intensity of immunofluorescence of vimentin was increased; the filaments of vimentin became thicker than those of normal macrophages when they were treated with colchicine; and the arrangement of vimentin filaments was parallel in direction to the polarization of the activated macrophages.
Su
Y X
YX
Department of Pathology, Shanghai Second Medical University.
D000818:Animals; D001428:Bacterial Vaccines / Q000627:therapeutic use; D003352:Corynebacterium / Q000276:immunology; D008262:Macrophage Activation; D008264:Macrophages / Q000378:metabolism*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D010529:Peritoneal Cavity / Q000166:cytology; D014746:Vimentin / Q000378:metabolism*
D001428:Bacterial Vaccines; D014746:Vimentin