Trial of low versus high osmolar contrast media in endoscopic retrograde cholangiopancreatography.
A double-blind trial of low versus high osmolar contrast media in ERCP was performed. The results provide convincing evidence that the incidence of both biochemical and clinical pancreatitis is higher when the conventional high osmolar medium is used. It is therefore suggested that low ionic contrast media should be used routinely in ERCP.
Banerjee
A K
AK
Gastrointestinal Laboratory, Rayne Institute, St Thomas' Hospital Medical School, London.
Grainger
S L
SL
Thompson
R P
RP
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000379:methods*; D003287:Contrast Media / Q000009:adverse effects*; D003974:Diatrizoate Meglumine; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007472:Iohexol; D008297:Male; D008875:Middle Aged; D009994:Osmolar Concentration; D010195:Pancreatitis / Q000139:chemically induced; D011446:Prospective Studies
D003287:Contrast Media; D003974:Diatrizoate Meglumine; D007472:Iohexol