Influence of dietary protein and recombinant porcine somatotropin administration in young pigs: growth, body composition and hormone status.
The influence of dietary protein and recombinant porcine somatotropin (rpST) administration on growth and body composition was investigated in barrows. Ten groups of six pigs starting at 30 kg were restrictively fed (approximately 80% of ad libitum) one of five diets containing 11, 15, 19, 23 or 27% protein. Diets contained skim milk (12%). Soybean meal diluted with cornstarch was used as the supplemental source of dietary protein. Diets were isocaloric (3.8 Mcal DE/kg) and all contained the same amount of lysine (18 to 20 g/kg). Thirty pigs were treated daily with rpST (100 micrograms/kg) by i.m. injection; the remaining pigs were treated with sterile diluent (control) for 42 d. Growth rate was greater in rpST-treated pigs at all levels of protein intake; however, the magnitude of the response to rpST treatment was lowest among pigs fed the diet containing 11% protein. Feed:gain ratio, backfat depth and carcass fat content were decreased in rpST-treated pigs compared to respective controls. Additionally, the concentration of carcass fat decreased concomitantly with an increase in dietary protein intake. Concentration of carcass protein increased linearly as dietary protein increased in control and rpST-treated pigs. In contrast, treatment with rpST was associated with an increased visceral mass; the concentration of protein and fat in the viscera was influenced by protein intake but not by rpST. These results, characterized by few treatment interactions, suggest that when energy intake is kept constant and appropriately fed pigs serve as controls, dietary protein and rpST influence growth and body composition by independent mechanisms.(ABSTRACT TRUNCATED AT 250 WORDS)
Caperna
T J
TJ
U.S. Department of Agriculture, Beltsville, MD 20705.
Steele
N C
NC
Komarek
D R
DR
McMurtry
J P
JP
Rosebrough
R W
RW
Solomon
M B
MB
Mitchell
A D
AD
D000273:Adipose Tissue / Q000254:growth & development; D000818:Animals; D001823:Body Composition / Q000187:drug effects*; D004044:Dietary Proteins / Q000008:administration & dosage / Q000378:metabolism*; D005934:Glucagon / Q000097:blood; D013006:Growth Hormone / Q000097:blood / Q000494:pharmacology*; D006321:Heart / Q000254:growth & development; D006728:Hormones / Q000097:blood*; D006854:Hydrocortisone / Q000097:blood; D007328:Insulin / Q000097:blood; D007334:Insulin-Like Growth Factor I / Q000032:analysis; D007668:Kidney / Q000254:growth & development; D008099:Liver / Q000254:growth & development; D008297:Male; D009929:Organ Size / Q000187:drug effects; D014176:Protein Biosynthesis; D011506:Proteins / Q000187:drug effects; D011994:Recombinant Proteins / Q000494:pharmacology; D013552:Swine / Q000097:blood / Q000254:growth & development*; D014781:Viscera / Q000187:drug effects / Q000254:growth & development; D015430:Weight Gain / Q000187:drug effects
D004044:Dietary Proteins; D006728:Hormones; D007328:Insulin; D011506:Proteins; D011994:Recombinant Proteins; D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone; D005934:Glucagon; D006854:Hydrocortisone