Occurrence of MRI abnormalities in patients with isolated optic neuritis.
24 patients with clinically isolated optic neuritis (ON) were examined with MRI. Only 5 patients (22.9%) had a normal MRI scan. The number of detected clinically silent lesions ranged from 0 to 38. They were mainly located in the frontal and parietal white matter. All patients with more than 3 lesions on MRI had pathological findings in CSF. There was no correlation between the number and location of lesions and age at onset of ON.
Städt
D
D
Max-Planck-Society, Clinical Research Unit for Multiple Sclerosis, FRG.
Kappos
L
L
Rohrbach
E
E
Heun
R
R
Ratzka
M
M
D000328:Adult; D005260:Female; D005625:Frontal Lobe / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009902:Optic Neuritis / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D010296:Parietal Lobe / Q000473:pathology