N-cadherin detected in the membrane fraction of lens fiber cells.
N-cadherin was identified as a glycoprotein present in the fiber cell membranes of frog, chick, bovine, rabbit and human lenses. The molecular size of N-cadherin varies with the species. Homogenization of the chick lens in the presence of Ca2+ resulted in a decrease in the concentration of N-cadherin. This suggests that the lens contains a Ca2(+)-activated protease which can act on N-cadherin.
Maisel
H
H
Department of Anatomy/Cell Biology, Wayne State University, School of Medicine, Detroit, Michigan 48201.
Atreya
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P
D000818:Animals; D015153:Blotting, Western; D015820:Cadherins / Q000032:analysis*; D002417:Cattle; D002462:Cell Membrane / Q000032:analysis; D002645:Chickens; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007908:Lens, Crystalline / Q000032:analysis*; D011817:Rabbits; D011894:Rana pipiens
D015820:Cadherins