[Comparison of the in vitro antibacterial activity of ofloxacin and nalidixic acid].
The in-vitro activity of ofloxacin and nalidixic acid was determined against 964 Gram-negative and 66 Gram-positive isolates from different clinical specimens. Ofloxacin showed excellent in vitro activity against Enterobacteriaceae. The compound was significantly more potent than nalidixic acid against Pseudomonas spp. Acinetobacter spp. and Staphylococcus spp. We conclude from our studies that ofloxacin could be a valuable therapeutic agent with a variety of indications.
Hasçelik
G
G
Hacettepe Universitesi Tip Fakültesi, Mikrobiyoloji Anabilim, Dali.
Baykal
M
M
D000150:Acinetobacter / Q000187:drug effects; D001419:Bacteria / Q000187:drug effects*; D004755:Enterobacteriaceae / Q000187:drug effects; D006801:Humans; D009268:Nalidixic Acid / Q000494:pharmacology*; D015242:Ofloxacin / Q000494:pharmacology*; D011549:Pseudomonas / Q000187:drug effects; D013210:Staphylococcus / Q000187:drug effects
D009268:Nalidixic Acid; D015242:Ofloxacin
Ofloxacin ve nalidixic acidin in vitro antibakteriyel aktivitelerinin karşilaştirilmasi.