Hereditary non-polyposis colorectal cancer in a Namaqualand kindred.
A family with hereditary non-polyposis colonic cancer affecting 16 males over three generations is described. Autosomal dominant inheritance with male predominance is demonstrated. The clinical features of this condition and methods for screening family members are discussed.
Goldblatt
J
J
Department of Human Genetics, University of Cape Town.
Madden
M V
MV
Boshoff
P J
PJ
Wallis
C
C
Price
S K
SK
D000328:Adult; D000368:Aged; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D013019:South Africa