title: Repair of osteochondral defects in the rabbit knee with Gore-Tex (expanded polytetrafluoroethylene). An experimental study.
abstract: In 28 knee joints in 14 rabbits 4 mm circular osteochondral defects were created in each medial femoral condyle. In 24 of the knee joints 4 mm Gore-Tex (E-PTFE) patches were glued into the defects with fibrin glue. Four joints were left without implants and served as controls. In 16 joints the membrane showed good macroscopic incorporation into the joint surface. In four joints the E-PTFE patches were lying loose. In the controls the defects were covered by thin irregular layers of reparative tissue. On histological examination at 12 weeks, cells were seen proliferating through the membrane and overlying its joint facing surface with the morphological appearance of the outer layers of the normal articular surface. We conclude that Gore-Tex might be of potential value in restoring the architecture of a damaged articular surface.
authors.affiliation: Department of Orthopaedic Surgery, Lund University Hospital, Sweden.
authors.forename: G
authors.initials: G
authors.lastname: Hanff
authors.forename: C
authors.initials: C
authors.lastname: Sollerman
authors.forename: S O
authors.initials: SO
authors.lastname: Abrahamsson
authors.forename: G
authors.initials: G
authors.lastname: Lundborg
mesh_terms: D000818:Animals; D002358:Cartilage, Articular / Q000473:pathology / Q000601:surgery; D005269:Femur / Q000473:pathology / Q000601:surgery; D007719:Knee Joint / Q000473:pathology / Q000601:surgery*; D011138:Polytetrafluoroethylene; D019736:Prostheses and Implants; D011817:Rabbits
chemical_list: D011138:Polytetrafluoroethylene