title: Epidermolysis bullosa: report of one case.
abstract: Epidermolysis bullosa (EB) is a group of inherited skin diseases manifested as bullae formation induced by minor trauma. According to the anatomical level of skin splitting, it could be classified mainly into three types: simplex, junctional and dystrophic EB. We have a female term newborn noted to have had skin defect and ulceration over lower legs concurrent with oral mucosal ulceration and blister formation since birth. New blisters occurred over friction and pressure areas shortly after birth. The histopathologic pictures revealed dystrophic type of EB. These lesions seemed responsive to phenytoin and topical skin care, healing gradually with minimal scarring and atrophy. However, it is important to follow these patients to help alleviate complications of extracutaneous involvement which may occur during later life.
authors.affiliation: Department of Pediatrics, Taiwan Provincial Tao-Yuan General Hospital, R.O.C.
authors.forename: S L
authors.initials: SL
authors.lastname: Yen
authors.forename: L H
authors.initials: LH
authors.lastname: Chao
authors.forename: M M
authors.initials: MM
authors.lastname: Ho
authors.forename: K C
authors.initials: KC
authors.lastname: Hwang
mesh_terms: D004820:Epidermolysis Bullosa / Q000145:classification / Q000473:pathology* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D011296:Prenatal Diagnosis