[The therapeutic effect of somofilin in bronchial asthma patients].
The sustained release theophylline drug Somophylline in capsules was applied in 21 asthmatic patients (12 women and 9 men), mean age 44.5 years in the course of 14 days in hospital conditions. The dose of the drug was 9-10 mg/kg body mass (24 h given in two equal doses in 12 h intervals). The effect was favourable in 17 patients (80.95%), weak--in 2 patients (9.52%) and no effect in 2 patients (9.52%). Somophylline is very well tolerated. The blood level remains in the therapeutic ranges during the treatment (about 10 micrograms/ml).
Kosturkov
G
G
Staneva
M
M
Mileva
Zh
Zh
Gerzilova
S
S
Slavov
S
S
Dimitrov
V
V
Vŭlcheva
T
T
Popov
T
T
D000328:Adult; D000368:Aged; D000628:Aminophylline / Q000009:adverse effects / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy*; D002214:Capsules; D003692:Delayed-Action Preparations; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D002214:Capsules; D003692:Delayed-Action Preparations; D000628:Aminophylline
Lecheben efekt na somofilin pri bolni ot bronkhialna astma.