[The dynamics of the enzymatic activity of DNA metabolism during the treatment of stomach cancer patients].
The activity of thymidine kinase was found to be distinctly elevated while the activity of thymidine phosphorylase was markedly reduced in the blood serum of patients with gastric cancer. The dynamics of enzymatic activity depended on the form of surgical intervention. In patients undergoing chemotherapy positive effects were observed in those with a high initial activity of thymidine phosphorylase. This enzyme test is recommended for determination of treatment efficiency and prognosis of the course of the disease.
Borzenko
B G
BG
Gorbachev
A A
AA
Dumanskiĭ
Iu V
IuV
Efimova
I A
IA
D004796:Clinical Enzyme Tests; D003131:Combined Modality Therapy; D004273:DNA, Neoplasm / Q000187:drug effects / Q000378:metabolism*; D005472:Fluorouracil / Q000627:therapeutic use; D005743:Gastrectomy; D006801:Humans; D008875:Middle Aged; D011182:Postoperative Care; D011379:Prognosis; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000628:therapy; D013937:Thymidine Kinase / Q000097:blood*; D013939:Thymidine Phosphorylase / Q000097:blood*
D004273:DNA, Neoplasm; D013939:Thymidine Phosphorylase; D013937:Thymidine Kinase; D005472:Fluorouracil
Dinamika aktivnosti fermentov metabolizma DNK v protsesse lecheniia bol'nykh bol'nykh rakom zheludka.