title: Progressive degeneration of the right temporal lobe studied with positron emission tomography.
abstract: A 79 year old man with a twelve year progressive history of prosopagnosia and recent naming difficulty, in whom other intellectual skills were preserved, is described. Positron emission tomography (PET) revealed an area of right temporal lobe hypometabolism, with an additional area of less severe hypometabolism at the left temporal pole. This may represent an example of progressive focal cortical degeneration similar to that associated with primary progressive dysphasia, but affecting the right temporal lobe.
authors.affiliation: Medical Research Council Cyclotron Unit, Hammersmith Hospital, London, United Kingdom.
authors.forename: P J
authors.initials: PJ
authors.lastname: Tyrrell
authors.forename: E K
authors.initials: EK
authors.lastname: Warrington
authors.forename: R S
authors.initials: RS
authors.lastname: Frackowiak
authors.forename: M N
authors.initials: MN
authors.lastname: Rossor
mesh_terms: D000368:Aged; D000377:Agnosia / Q000150:complications / Q000175:diagnosis; D001927:Brain Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000378:metabolism*; D002560:Cerebrovascular Circulation; D003072:Cognition Disorders / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D010101:Oxygen Consumption; D010104:Oxygen Radioisotopes / Q000378:metabolism; D013702:Temporal Lobe / Q000000981:diagnostic imaging / Q000378:metabolism*; D014055:Tomography, Emission-Computed
chemical_list: D010104:Oxygen Radioisotopes