title: [Effect of biliary obstruction and cholangitis on serum SPan-1 level].
abstract: We investigated the effect of biliary obstruction and cholangitis on serum SPan-1 level in 14 patients (5 patients with pancreatic cancer and 9 patients with biliary tract cancer) who were performed PTCD for biliary obstruction. 1 out of 5 cases with pancreatic cancer and 8 out of 9 cases with biliary tract cancer showed a decrease of SPan-1 level with improvement of jaundice. It suggested that the effect of biliary obstruction and cholangitis on serum SPan-1 level was much more in biliary tract cancer than in pancreatic cancer. There was no significant difference in changes of between serum SPan-1 level and serum CA 19-9 level after PTCD. We conclude that the effect of biliary obstruction and cholangitis on serum SPan-1 level is almost same on serum CA 19-9 level.
authors.affiliation: Department of Radiology, National Fukuoka Central Hospital.
authors.forename: S
authors.initials: S
authors.lastname: Matsumoto
authors.forename: T
authors.initials: T
authors.lastname: Muranaka
authors.forename: K
authors.initials: K
authors.lastname: Hanada
authors.forename: Y
authors.initials: Y
authors.lastname: Matsuura
authors.forename: Y
authors.initials: Y
authors.lastname: Oshiumi
mesh_terms: D000951:Antigens, Neoplasm / Q000032:analysis*; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis; D001661:Biliary Tract Neoplasms / Q000097:blood*; D014408:Biomarkers, Tumor / Q000032:analysis*; D002761:Cholangitis / Q000097:blood*; D002779:Cholestasis / Q000097:blood* / Q000601:surgery; D006801:Humans; D010190:Pancreatic Neoplasms / Q000097:blood*
chemical_list: D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor; C059729:pancreatic associated antigen, SPan-1