[The characteristics of the proliferative processes in the epithelium of the sigmoid intestine in acute bacillary dysentery].
Proliferative processes were studied using radioautography with 3H-thymidine at the height of the disease and in the early convalescence of the bacterial dysentery. The mucous membrane of the sigmoid colon of healthy persons undergoing rectoromanoscopy due to the epidemic reasons served as control. No pathologic changes were found in these healthy persons; the labeled nuclei index (LNI) was 5.75 +/- 0.4%, the label intensity (LI) characterizing the rate of DNA synthesis was 14.9 +/- 0.8. During the peak of bacterial dysentery LNI increased up to 12.9 +/- 1.3% and there was a three-fold increase of LI. Activation of the proliferative processes persisted in the period of an early recovery. LNI was 9.4 +/- 1.0%, LI was 2.6 times higher as compared to control.
Borovskaia
T F
TF
Timoshin
S S
SS
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001345:Autoradiography; D001706:Biopsy; D002455:Cell Division / Q000502:physiology; D012809:Colon, Sigmoid / Q000378:metabolism / Q000473:pathology*; D003289:Convalescence; D004247:DNA / Q000096:biosynthesis; D004405:Dysentery, Bacillary / Q000378:metabolism / Q000473:pathology*; D004848:Epithelium / Q000378:metabolism / Q000473:pathology; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000378:metabolism / Q000473:pathology*; D008297:Male; D012763:Shigella flexneri; D012764:Shigella sonnei; D012812:Sigmoidoscopy
D004247:DNA
Kharakteristika proliferativnykh protsessov v épitelii sigmoidnoĭ kishki pri ostroĭ bakterial'noĭ dizenterii.