title: Intersecting staple lines and blood flow in oesophagojejunal anastomoses.
abstract: Total gastrectomy and oesophagojejunostomy with linear stapling devices were performed on 22 pigs to evaluate whether intersecting staple lines reduce the blood flow with an increased risk of anastomotic leakage. The blood flow at intersecting staple lines and single row staple lines of the anastomosis was studied with the reference organ method 24 h after the first operation. The mean blood flow in intersecting staple lines was 0.305 ml min-1 g-1 tissue and 0.307 ml min-1 g-1 tissue for single row staple lines. The confidence interval for the reduction in blood flow for intersecting staple lines compared with non-crossing staple lines was from -16 to +17 per cent. In one animal the reduction in blood flow was 37 per cent; in all other animals there was no reduction in blood flow or a reduction less than 25 per cent. An equivalence test shows that if a reduction in blood flow exists it is most likely to be less than 30 per cent (P less than 0.001). Our data confirm that intersecting staple lines in oesophagojejunal anastomoses do not reduce mean anastomotic blood flow to a dangerous level.
authors.affiliation: Department of Surgery, Lund University, Sweden.
authors.forename: T L
authors.initials: TL
authors.lastname: Zilling
authors.forename: B S
authors.initials: BS
authors.lastname: Walther
authors.forename: J
authors.initials: J
authors.lastname: Ranstam
mesh_terms: D000713:Anastomosis, Roux-en-Y; D000714:Anastomosis, Surgical; D000818:Animals; D016001:Confidence Intervals; D004947:Esophagus / Q000601:surgery*; D005260:Female; D005743:Gastrectomy; D007583:Jejunum / Q000601:surgery*; D008297:Male; D008833:Microcirculation / Q000502:physiology; D012039:Regional Blood Flow / Q000502:physiology; D013528:Surgical Staplers; D013536:Suture Techniques; D013552:Swine