Acute rejection and endomyocardial biopsy after heart transplantation.
The paper presents the experience with acute rejection and endomyocardial biopsy in heart transplantation in 28 patients over a period of five years. The authors regards endomyocardial biopsy as a sensitive marker of acute rejection, especially in patients on long-term cyclosporin immunosuppression. Some aspects of episodes of incipient acute rejection and mild acute rejection as well as their therapy are discussed.
Urbanová
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Institute for Clinical and Experimental Medicine, Prague, Czechoslovakia.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D003524:Cyclosporins / Q000627:therapeutic use; D004699:Endocardium / Q000473:pathology*; D006084:Graft Rejection; D016027:Heart Transplantation / Q000276:immunology / Q000473:pathology*; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008775:Methylprednisolone / Q000494:pharmacology; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology*; D013997:Time Factors
D003524:Cyclosporins; D008775:Methylprednisolone