[The clinical aspects of using plasmapheresis in sepsis].
The rise of the sepsis incidence at therapeutic hospitals, the emergence of new forms and evolutionally new mechanisms of infection, insufficient efficacy of antibacterial therapy necessitate the search of novel approaches to the treatment of sepsis. The use of plasmapheresis (PP) in 27 sepsis patients allowed a two-fold reduction of the lethality as compared to that in the control group. The main mechanisms by which PP acts may involve deblockade of the system of phagocytosing mononuclears, enhancement of the efficacy of antibacterial therapy, protective action on the system of natural detoxication of the body.
Gorshkov
M P
MP
Fil'ko
V N
VN
Borisenko
A P
AP
Evseev
N G
NG
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000917:Antibody Formation; D001424:Bacterial Infections / Q000276:immunology / Q000628:therapy*; D003131:Combined Modality Therapy; D006801:Humans; D007111:Immunity, Cellular; D008875:Middle Aged; D010956:Plasmapheresis; D018805:Sepsis / Q000276:immunology / Q000628:therapy; D013997:Time Factors
Klinicheskie aspekty primeneniia plazmafereza pri sepsise.