title: [Characteristics of immunologic homeostasis in the late period after reconstructive operations on the heart valves].
abstract: The immune status, i.e. T and B lymphocytes and their populations, was assessed after heart valve replacement or reconstruction in 70 patients with acquired heart defects. In 30%, the immune status was found to be normal which corresponded to inactive rheumatic process in these patients; 40% showed activated immunity manifested by increased T-active, T-total, T-helper, and T-suppressor numbers compared to the first group, which corresponded to activation of a rheumatic process in these patients. The rest 30% patients showed suppressed immunity, i.e. diminished subpopulations of T lymphocytes and B lymphocytes. These changes were detected in patients with circulatory insufficiency and progressive septic endocarditis. This allows for a conclusion that determination of the status of immunity and its correction are essential for cardiac surgery patients.
authors.forename: R A
authors.initials: RA
authors.lastname: Liudinovskova
authors.forename: G V
authors.initials: GV
authors.lastname: Gromova
authors.forename: S T
authors.initials: ST
authors.lastname: Tsygankova
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Tarichko
authors.forename: V A
authors.initials: VA
authors.lastname: Ivanov
authors.forename: K A
authors.initials: KA
authors.lastname: Buniatian
authors.forename: N I
authors.initials: NI
authors.lastname: Akimova
authors.forename: L V
authors.initials: LV
authors.lastname: Tokareva
mesh_terms: D001021:Aortic Valve / Q000601:surgery*; D001402:B-Lymphocytes / Q000276:immunology*; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D007958:Leukocyte Count; D008231:Lymphopenia / Q000209:etiology; D008297:Male; D008943:Mitral Valve / Q000601:surgery*; D011184:Postoperative Period; D012214:Rheumatic Heart Disease / Q000276:immunology / Q000601:surgery*; D013601:T-Lymphocytes / Q000276:immunology*; D013997:Time Factors
vernacular_title: Osobennosti immunnogo gomeostaza v otdalennom periode posle rekonstruktivnykh operatsiĭ na klapanakh serdtsa.