Molecular mechanisms of the hepatotoxicity caused by acetaminophen.
Nelson
S D
SD
Department of Medicinal Chemistry, University of Washington, Seattle 98195.
D000082:Acetaminophen / Q000009:adverse effects*; D000818:Animals; D016227:Benzoquinones / Q000378:metabolism; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D004347:Drug Interactions; D006801:Humans; D007097:Imines / Q000378:metabolism; D008099:Liver / Q000187:drug effects* / Q000378:metabolism
D016227:Benzoquinones; D007097:Imines; D000082:Acetaminophen; C028473:N-acetyl-4-benzoquinoneimine