title: Screening of seven putative 45,X subjects with deoxyribonucleic acid probes to detect low-level mosaicism for Y cell lines.
abstract: The frequency of monosomy X in cytogenetically abnormal abortion material (10% to 15%) suggests that viable 45,X subjects might have covert mosaicism for X or Y cell lines. The deoxyribonucleic acid samples from seven 45,X subjects with Turner syndrome were examined with three Y-specific deoxyribonucleic acid probes. Successive hybridizations with each of these three sensitive deoxyribonucleic acid probes did not reveal any Y-specific band.
authors.affiliation: Department of Obstetrics and Gynecology, Medical College of Georgia, Augusta 30912.
authors.forename: S P
authors.initials: SP
authors.lastname: Tho
authors.forename: A
authors.initials: A
authors.lastname: Behzadian
authors.forename: P G
authors.initials: PG
authors.lastname: McDonough
mesh_terms: D002460:Cell Line; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D015342:DNA Probes; D005260:Female; D006801:Humans; D009006:Monosomy; D009030:Mosaicism; D009693:Nucleic Acid Hybridization; D014424:Turner Syndrome / Q000235:genetics; D014960:X Chromosome; D014998:Y Chromosome
chemical_list: D015342:DNA Probes