title: [Developmental profile of HIV infection in children].
abstract: The natural history of HIV-1 infection in children has not yet been determined precisely. Contrary to what is observed in adults, the disease seems to follow a bimodal course. One-quarter to one-third of infected children develop, before the end of their first year of life, a deep immunodeficiency which is responsible for severe infectious and neurological symptoms; survival does not exceed 4 to 5 years. In contrast, although the other children are symptomatic, their disease progresses much more slowly, perhaps as slowly as in adults, and their long-term outcome remains uncertain.
authors.affiliation: Hôpital Necker, service d'immunologie et d'hématologie, Paris.
authors.forename: S
authors.initials: S
authors.lastname: Blanche
mesh_terms: D005260:Female; D015658:HIV Infections / Q000453:epidemiology* / Q000635:transmission; D006679:HIV Seropositivity; D006801:Humans; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange / Q000276:immunology*; D011247:Pregnancy; D011446:Prospective Studies; D012189:Retrospective Studies
vernacular_title: Profil évolutif de l'infection à VIH de l'enfant.