title: Primary malignant liver tumors in childhood: assessment of resectability with high-field MR and comparison with CT.
abstract: Nine children (mean age 20 months), with proven primary malignant hepatic tumors have been examined prospectively by high-field magnetic resonance (MR) imaging to assess tumor resectability. All patients had comparative ultrasonography (US), 8 patients had X-Ray computed tomography (CT), and surgical correlation was available in 8 patients. The hepatic and portal veins and the inferior vena cava were visualized in all patients on MR and in 4 of 8 patients on CT. MR accurately defined liver parenchymal involvement in all 8 patients who had surgical exploration. CT underestimated disease in 2 cases, and defined tumour margins less clearly than MR. MR identified abnormal extrahepatic tissue when present, but was unable to distinguish viable tumor from necrotic tumor or reactive nodes. High quality short TR/short TE spin echo images were obtained by combining cardiac triggering and signal averaging. Short TI inversion recovery images demonstrated tumor and lymphadenopathy most clearly. We conclude that MR is the imaging method of choice for the assessment of liver tumor resectability in children.
authors.affiliation: Department of Radiology, Hospital for Sick Children, London, UK.
authors.forename: J P
authors.initials: JP
authors.lastname: Finn
authors.forename: M A
authors.initials: MA
authors.lastname: Hall-Craggs
authors.forename: C
authors.initials: C
authors.lastname: Dicks-Mireaux
authors.forename: L
authors.initials: L
authors.lastname: Spitz
authors.forename: E R
authors.initials: ER
authors.lastname: Howard
authors.forename: J
authors.initials: J
authors.lastname: Pritchard
authors.forename: G M
authors.initials: GM
authors.lastname: Vergani
mesh_terms: D002675:Child, Preschool; D003287:Contrast Media; D006503:Hepatic Veins / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007089:Image Enhancement; D007223:Infant; D007231:Infant, Newborn; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D008279:Magnetic Resonance Imaging / Q000379:methods; D011169:Portal Vein / Q000000981:diagnostic imaging / Q000473:pathology; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods; D014463:Ultrasonography
chemical_list: D003287:Contrast Media