Preserved organization of semantic attributes in Alzheimer's disease.
This study investigated whether Alzheimer's disease (AD) disrupts the basic organization of the semantic attributes of concepts. Young and normal older subjects and AD patients were presented with a target concept followed by a stimulus word and were to decide whether the stimulus was related to the target. On those trials where it was, the stimulus was either a high-, medium-, or low-dominance attribute of the target. The higher the normative dominance, the more important the attribute to concept meaning. In all 3 subject groups, decision time varied as a function of dominance. The higher the dominance, the faster the decision. Attribute dominance affected the performance of AD patients more than that of normal subjects. These results suggest that AD patients retain their knowledge of the relative importance that the different attributes of a concept have for concept meaning.
Nebes
R D
RD
Department of Psychiatry, University of Pittsburgh, Pennsylvania 15213.
Brady
C B
CB
D000328:Adult; D000368:Aged; D000544:Alzheimer Disease / Q000523:psychology*; D003210:Concept Formation; D003657:Decision Making; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory; D011569:Psychiatric Status Rating Scales; D012660:Semantics; D014936:Word Association Tests