title: [Diuretic-induced edema].
abstract: The diagnosis of "diuretic-induced oedema" was made in 17 women (mean age 42.4 [23-60] years) who had developed generalized oedema after stopping their (chronic) intake of diuretics. Five patients were between 11 and 32% overweight, five of them were unusually old. A further four patients had severe concomitant diseases, such as primary lymphoedema, mitral valve defect and lupus erythematosus. In 10 of the 17 discontinuation was successful: the initial weight gain averaged 3.9 (1.5-7.5) kg. The maximal weight-gain, in a woman in the course of weaning her of the diuretic, was reversed within 20 days. Diuretic withdrawal after more than 20 years in a woman with mitral valve disease caused heart failure. Diuretic abuse caused prerenal failure in one women, but renal function became normal again after stopping of the diuretic and rehydration.
authors.affiliation: Medizinische Poliklinik, Universität München.
authors.forename: M
authors.initials: M
authors.lastname: Middeke
authors.forename: W
authors.initials: W
authors.lastname: Pinter
authors.forename: M
authors.initials: M
authors.lastname: Jahn
authors.forename: H
authors.initials: H
authors.lastname: Holzgreve
mesh_terms: D000328:Adult; D001835:Body Weight / Q000187:drug effects; D004232:Diuretics / Q000009:adverse effects*; D004487:Edema / Q000139:chemically induced / Q000175:diagnosis; D005260:Female; D006801:Humans; D008875:Middle Aged; D012651:Self Medication / Q000009:adverse effects; D013375:Substance Withdrawal Syndrome / Q000175:diagnosis / Q000209:etiology; D013997:Time Factors
chemical_list: D004232:Diuretics
vernacular_title: Diuretika-induzierte Odeme.