title: Severe disseminated staphylococcal disease associated with osteitis and septic arthritis.
abstract: We reviewed the records of 1,156 patients treated for acute staphylococcal osteitis or septic arthritis over a 12-year period; 38 had been critically ill with evidence of multiple-organ involvement and 30 (79%) had features of the toxic shock syndrome. The mortality rate of these 38 patients was 13% and the long-term orthopaedic complication rate was 39%. The diagnosis and management of patients with osteitis or septic arthritis, disseminated staphylococcal disease, and the toxic shock syndrome is discussed.
authors.affiliation: Red Cross Children's Hospital, Cape Town, Republic of South Africa.
authors.forename: M P
authors.initials: MP
authors.lastname: Paterson
authors.forename: E B
authors.initials: EB
authors.lastname: Hoffman
authors.forename: P
authors.initials: P
authors.lastname: Roux
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D001170:Arthritis, Infectious / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D001842:Bone and Bones / Q000000981:diagnostic imaging; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010000:Osteitis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D011859:Radiography; D012772:Shock, Septic / Q000150:complications; D013203:Staphylococcal Infections / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology