title: Cadmium contamination of the countryside, a case study on health effects.
abstract: The border region between Belgium and The Netherlands, the Kempen, was found to be polluted with cadmium. The main route of pollution had been by air but some cadmium came by way of surface-water and solid waste. This resulted in an increase in the cadmium content of locally grown vegetables. The consequential exposure to cadmium of humans living in the area has been estimated using various methods and is approximately the FAO/WHO maximum allowable daily intake, smoking disregarded. Several studies of possible effects on public health were conducted. Among these studies were two geographic studies, one on hospital admissions for various non-malignant diseases and one on cancer-incidence. Two cohort studies on possible teratogenic effects in a non-occupationally exposed, non-smoking vegetarian population with a high fertility and good registration were also conducted. A survey on cadmium content of the urine and kidney damage in a longtime but non-occupationally exposed rural population and a reference population formed the main study. Also, a survey on cadmium content of the kidney samples of autopsied patients in a population based study and a reference population was conducted. Together these studies showed that the extra exposure had lead to an additional body-burden of cadmium resulting in various signs of malfunction. In consequence of the findings the Netherlands Ministry for Housing, Physical Planning and Environment appropriated money to cleanup contaminated gardens.
authors.affiliation: Division of Epidemiology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands.
authors.forename: I A
authors.initials: IA
authors.lastname: Kreis
mesh_terms: D002104:Cadmium / Q000009:adverse effects*; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D004785:Environmental Pollutants / Q000009:adverse effects*; D006801:Humans; D009426:Netherlands; D012423:Rural Health
chemical_list: D004785:Environmental Pollutants; D002104:Cadmium