title: Standardized non-invasive assessment of myocardial free fatty acid kinetics by means of 15-(para-iodo-phenyl) pentadecanoic acid (123I-pPPA)scintigraphy: I. Method.
abstract: Two simple mathematical functions have been applied for estimating myocardial perfusion and fatty acid metabolism from planar, dynamic 123I-para-phenylpentadecanoic acid (123I-pPPA) studies. The first one uses a modified gamma function and the latter one a biexponential fit. The reciprocal of mean transit time is assumed to represent myocardial blood flow and the fast phase (size and half-time) of the biexponential fit primarily accounts for beta oxidation of 123I-pPPA.
authors.affiliation: Department of Nuclear Medicine, Koblenz, FRG.
authors.forename: H
authors.initials: H
authors.lastname: Wieler
authors.forename: K P
authors.initials: KP
authors.lastname: Kaiser
authors.forename: J
authors.initials: J
authors.lastname: Frank
authors.forename: J T
authors.initials: JT
authors.lastname: Kuikka
authors.forename: K
authors.initials: K
authors.lastname: Ladwein
authors.forename: A
authors.initials: A
authors.lastname: Winkens
mesh_terms: D003326:Coronary Circulation; D005227:Fatty Acids; D005230:Fatty Acids, Nonesterified / Q000378:metabolism*; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D007700:Kinetics; D009206:Myocardium / Q000378:metabolism*; D011877:Radionuclide Imaging; D013997:Time Factors
chemical_list: D005227:Fatty Acids; D005230:Fatty Acids, Nonesterified; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; C049338:iodofiltic acid