Cytogenetic analysis of peripheral blood lymphocytes in workers exposed to vinyl chloride.
In the present study, the method of cytogenetic analysis of peripheral blood lymphocytes was used to examine 43 workers exposed to vinyl chloride monomer (average exposure 11.2 years) and 22 subjects selected from the same locality (control group). A total number of 8650 metaphases were analysed. All cytogenetic parameters examined were increased in the exposed group as compared to the control group and 3 parameters, chromatid breaks, percentage of aberrant cells and breaks per cell, were significantly increased (P less than 0.001).
Hrivnak
L
L
Regional Institute of Hygiene, Banska Bystrica, Czechoslovakia.
Rozinova
Z
Z
Korony
S
S
Fabianova
E
E
D000328:Adult; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000187:drug effects*; D004781:Environmental Exposure; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects* / Q000648:ultrastructure; D014752:Vinyl Chloride / Q000633:toxicity*; D014753:Vinyl Compounds / Q000633:toxicity*
D014753:Vinyl Compounds; D014752:Vinyl Chloride