title: [Up-date on atherosclerosis].
abstract: The major steps of the pathogenesis of atherosclerosis are now well defined. Efforts are still required to better characterize: 1. the cellular mechanisms of atherogenesis, without ignoring the limitations of the available experimental models; 2. the complications of human atherosclerosis, ie the events (ulceration, thrombosis) that provoke ischaemic manifestations. Four short reviews on topics of special interest follow: proliferation of arterial smooth muscle cells; interactions of blood cells (platelets, leukocytes) with the arterial wall; lipoproteins in the genesis of foam cells; recent progresses in genetic epidemiology of cardiovascular diseases.
authors.affiliation: Service du Pr J.-N. Fiessinger, hôpital Broussais, Paris.
authors.forename: L
authors.initials: L
authors.lastname: Capron
authors.forename: N
authors.initials: N
authors.lastname: Blaes
authors.forename: J L
authors.initials: JL
authors.lastname: Wautier
authors.forename: J
authors.initials: J
authors.lastname: Chapman
authors.forename: F
authors.initials: F
authors.lastname: Cambien
mesh_terms: D000818:Animals; D001161:Arteriosclerosis / Q000150:complications / Q000453:epidemiology / Q000209:etiology / Q000235:genetics; D001773:Blood Cells; D002450:Cell Communication; D002455:Cell Division; D005487:Foam Cells / Q000502:physiology; D006801:Humans; D008074:Lipoproteins / Q000378:metabolism; D009131:Muscle, Smooth, Vascular / Q000166:cytology
chemical_list: D008074:Lipoproteins
vernacular_title: Actualités de l'athérosclérose.