Effect of oral antacid administration on the pharmacokinetics of oral fluconazole.
Absorption and elimination of fluconazole after oral administration of a 100-mg capsule were unaffected by concomitant administration of an antacid containing aluminum and magnesium hydroxides.
Thorpe
J E
JE
Department of Clinical Research Pfizer Central Research, Sandwich, Kent United Kingdom.
Baker
N
N
Bromet-Petit
M
M
D000284:Administration, Oral; D000328:Adult; D000863:Antacids / Q000008:administration & dosage / Q000494:pharmacology*; D004347:Drug Interactions; D015725:Fluconazole / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D006801:Humans; D008297:Male
D000863:Antacids; D015725:Fluconazole