title: Distribution of aflatoxins in tissues of growing pigs fed an aflatoxin-contaminated diet amended with a high affinity aluminosilicate sorbent.
abstract: The effect of hydrated sodium calcium aluminosilicate (HSCAS) added to the diet of swine fed an aflatoxin-contaminated diet on tissue aflatoxin levels was investigated. Pigs were fed control (less than 10 ng/g B1 + B2), contaminated (500-600 ng/g B1 + B2), and contaminated +0.5% HSCAS diets. Tissues analyzed for the presence of aflatoxin B1, B2, and M1 residues included liver, muscle, kidney, and adipose. Addition of HSCAS to the contaminated diet significantly reduced the amount of M1 in liver, kidney, and muscle tissue. Aflatoxin B1 was not reduced in liver or kidney, but was decreased in muscle.
authors.affiliation: Coastal Plain Experiment Station, University of Georgia, Tifton 31793-0748.
authors.forename: R W
authors.initials: RW
authors.lastname: Beaver
authors.forename: D M
authors.initials: DM
authors.lastname: Wilson
authors.forename: M A
authors.initials: MA
authors.lastname: James
authors.forename: K D
authors.initials: KD
authors.lastname: Haydon
authors.forename: B M
authors.initials: BM
authors.lastname: Colvin
authors.forename: L T
authors.initials: LT
authors.lastname: Sangster
authors.forename: A H
authors.initials: AH
authors.lastname: Pikul
authors.forename: J D
authors.initials: JD
authors.lastname: Groopman
mesh_terms: D000348:Aflatoxins / Q000493:pharmacokinetics* / Q000633:toxicity; D000538:Aluminum Silicates; D000821:Animal Feed / Q000032:analysis*; D000818:Animals; D004032:Diet; D005260:Female; D005506:Food Contamination / Q000032:analysis*; D008297:Male; D013552:Swine; D014018:Tissue Distribution
chemical_list: D000348:Aflatoxins; D000538:Aluminum Silicates