title: Hypothyroidism and respiratory insufficiency in a neonatal foal.
abstract: Hypothyroidism was diagnosed in a neonatal Thoroughbred foal that was weak, hypothermic, and septicemic. Administration of thyroid-releasing hormone elicited attenuated increases in concentrations of free and total triiodothyronine and thyroxine, as compared with a clinically normal, age-matched foal. The foal died of apparent respiratory insufficiency, pre- and postmortem findings compatible with hypothyroidism included hypothermia, large thyroid glands with distended, colloid-filled follicles, and severe, diffuse atelectasis, with thickened alveolar septae and degenerating alveolar squamous epithelial cells.
authors.affiliation: Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Leesburg 22075.
authors.forename: M J
authors.initials: MJ
authors.lastname: Murray
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D005260:Female; D006734:Horse Diseases; D006736:Horses; D007037:Hypothyroidism / Q000150:complications / Q000662:veterinary*; D012131:Respiratory Insufficiency / Q000150:complications / Q000662:veterinary*; D013961:Thyroid Gland / Q000473:pathology; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
chemical_list: D014284:Triiodothyronine; D013974:Thyroxine