Prospective study utilizing transdermal scopolamine in detrusor instability.
Ten patients with pure detrusor instability were treated in a prospective fashion with transdermal scopolamine. Seventy percent of patients experienced moderate to severe untoward symptoms requiring discontinuation of medication. Three of 10 patients (30%) demonstrated a subjective improvement although only 1 was able to tolerate the medication. No objective change in detrusor instability was demonstrated.
Cornella
J L
JL
Department of Obstetrics and Gynecology, University of California, Irvine.
Bent
A E
AE
Ostergard
D R
DR
Horbach
N S
NS
D000279:Administration, Cutaneous; D006801:Humans; D010865:Pilot Projects; D011446:Prospective Studies; D012601:Scopolamine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001750:Urinary Bladder, Neurogenic / Q000188:drug therapy*
D012601:Scopolamine