title: [Antiulcer treatment with Biotidin and Gastrozepin and its effect on the occupational fitness of drivers and machinery operators].
abstract: The contemporary antiulcer treatment is performed with drugs which act unfavorably on the professional fitness on automobile and engine drivers. In 28 patients with newly discovered and untreated peptic ulcer disease the supporting treatment with Biotitin and Gastrozepin did not show unfavorable effect on the ability to concentrate, to fix the attention, fast choice of conduct and on the length of the latent period and the motion times. In comparison with 14 healthy persons the patients examined showed changes in their neurophysiological condition prior to the antiulcer treatment which correlate with the onset of the peptic ulcer disease, the disturbances of the prostaglandin synthesis and the development of functional beta-adrenergic protective reaction. The timely and modern antiulcer treatment is in the interest of safety of road traffic.
authors.forename: D
authors.initials: D
authors.lastname: Pekhlivanov
authors.forename: R
authors.initials: R
authors.lastname: Rankov
authors.forename: N
authors.initials: N
authors.lastname: Pekhlivanov
authors.forename: I
authors.initials: I
authors.lastname: Lambev
authors.forename: N
authors.initials: N
authors.lastname: Minkova
mesh_terms: D000328:Adult; D001334:Automobile Driving; D002031:Bulgaria; D004381:Duodenal Ulcer / Q000188:drug therapy / Q000503:physiopathology / Q000523:psychology; D004738:Engineering; D006801:Humans; D008875:Middle Aged; D010809:Physical Fitness / Q000502:physiology / Q000523:psychology; D010890:Pirenzepine / Q000627:therapeutic use*; D011597:Psychomotor Performance / Q000187:drug effects / Q000502:physiology; D011603:Psychophysiology; D011899:Ranitidine / Q000627:therapeutic use*; D013276:Stomach Ulcer / Q000188:drug therapy / Q000503:physiopathology / Q000523:psychology
chemical_list: D010890:Pirenzepine; D011899:Ranitidine
vernacular_title: Protivoiazveno lechenie s Biotidin i Gastrozepin i negovoto otrazhenie vŭrkhu profesionalnata godnost na shof'ori i mashinisti.