[Effect of dry ginger and roasted ginger on experimental gastric ulcers in rats].
This paper reports the effect of dry ginger and roasted ginger decoctions on four experimental gastric ulcer models in rats at an oral administration of 4.5 g/kg. The result shows that the roasted ginger has an obvious inhibiting tendency on three gastric ulcer models except the indomethacin induced model while the dry ginger has no such effects. The acute toxicity test has shown that the LD50 of roasted ginger decoction administered orally is 170.6 +/- 1.1 g/kg, but it is over 250 g/kg with dry ginger. This suggests that the water soluble constituents of the dry ginger have changed in the roasting process.
Wu
H
H
Nanjing College of Traditional Chinese Medicine.
Ye
D
D
Bai
Y
Y
Zhao
Y
Y
D000085:Acetates; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006358:Hot Temperature; D007213:Indomethacin; D008297:Male; D051379:Mice; D051381:Rats; D011919:Rats, Inbred Strains; D013276:Stomach Ulcer / Q000139:chemically induced / Q000188:drug therapy*; D013312:Stress, Physiological
D000085:Acetates; D004365:Drugs, Chinese Herbal; D007213:Indomethacin