Antibody persistence in splenectomized adults after pneumococcal vaccination.
16 splenectomized adults, all vaccinated with a 14-valent pneumococcal vaccine (Pneumovax) 1978-79 had their pneumococcal antibody concentrations measured before and up to 10 years after vaccination. The antibody concentrations after vaccination declined to 71% in 2 years and remained at this level during the 10-year study period. Further studies are needed to see whether this applies to all vaccinated splenectomized adults.
Konradsen
H B
HB
WHO Collaborating Centre for Reference and Research on Pneumococci, Statens Seruminstitut, Copenhagen, Denmark.
Nielsen
J L
JL
Pedersen
F K
FK
Henrichsen
J
J
D000907:Antibodies, Bacterial / Q000032:analysis* / Q000276:immunology; D001428:Bacterial Vaccines / Q000008:administration & dosage*; D006801:Humans; D022242:Pneumococcal Vaccines; D013156:Splenectomy; D013296:Streptococcus pneumoniae / Q000276:immunology*; D013997:Time Factors; D014611:Vaccination
D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines; D022242:Pneumococcal Vaccines