title: Heart rate and blood pressure: significance of the law of initial values.
abstract: Thirty normal controls, 30 panic-disorder patients and 19 depressed patients participated in a study involving postural and isometric handgrip tests. Prestimulus values of heart-rate and blood-pressure were correlated with stimulus phasic responses. The law of initial values did not hold during the change from supine to standing posture or during the isometric handgrip test for heart-rate and blood-pressure, but it held for heart-rate during the change from standing to supine posture. The effect of regression toward the mean was accounted for in the analyses.
authors.affiliation: Lafayette Clinic, Detroit, MI 48207.
authors.forename: V K
authors.initials: VK
authors.lastname: Yeragani
authors.forename: P C
authors.initials: PC
authors.lastname: Meiri
authors.forename: R
authors.initials: R
authors.lastname: Pohl
authors.forename: R
authors.initials: R
authors.lastname: Balon
authors.forename: B
authors.initials: B
authors.lastname: Merlos
mesh_terms: D000328:Adult; D000553:Ambulatory Care; D001008:Anxiety Disorders / Q000503:physiopathology; D001794:Blood Pressure / Q000502:physiology*; D003866:Depressive Disorder / Q000188:drug therapy / Q000503:physiopathology; D005260:Female; D006339:Heart Rate / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D007099:Imipramine / Q000494:pharmacology / Q000627:therapeutic use; D007537:Isometric Contraction / Q000502:physiology; D008297:Male; D010200:Panic; D005082:Physical Exertion / Q000502:physiology; D011187:Posture; D011603:Psychophysiology
chemical_list: D007099:Imipramine