title: [Enamel mineralization in rats subjected to an excess fluoride diet: SEM study].
abstract: Aim of our present work is to investigate with the SEM the process of enamel mineralization in the lower incisors of albino rats submitted for 21 days (a single amelogenetic cycle) to an hyperfluoric diet (five folds more than the normal). Our observations were performed on specimens fractured 8, 12 and 16 mm from the cervical loop transversally along the major axis of the incisor. It was demonstrated that the three different phases of enamel maturation were slower, so that, when the incisor erupted, mineralization was not completed and localized areas of demineralization were present. The authors are of the opinion that all morphological changes are dependent on the effect of fluoride on ameloblasts, either during their secretory or modulatory phases. On the basis of our results attention is pointed on the possible lesions of the enamel dependent from an unwary fluoride administration, particularly when decidual teeth are still present.
authors.affiliation: Dipartimento di Biomorfologia, Università di Messina.
authors.forename: G
authors.initials: G
authors.lastname: Anastasi
authors.forename: D
authors.initials: D
authors.lastname: Bruschetta
authors.forename: S
authors.initials: S
authors.lastname: De Leo
authors.forename: L
authors.initials: L
authors.lastname: Magaudda
authors.forename: G
authors.initials: G
authors.lastname: Santoro
authors.forename: F
authors.initials: F
authors.lastname: Trimarchi
mesh_terms: D000818:Animals; D003743:Dental Enamel / Q000648:ultrastructure*; D004032:Diet; D005459:Fluorides / Q000008:administration & dosage*; D005614:Freeze Fracturing; D007180:Incisor; D008855:Microscopy, Electron, Scanning; D051381:Rats; D011919:Rats, Inbred Strains; D013499:Surface Properties; D013997:Time Factors; D014074:Tooth Calcification
chemical_list: D005459:Fluorides
vernacular_title: Mineralizzazione dello smalto in ratti sottoposti a dieta iperfluorica: studio al MES.