Changes in sensory-cognitive input: effects on cerebral blood flow.
Eight healthy right-handed young men were subjected to local CBF measurement by [15O]water and positron emission tomography during partial sensory deprivation and during sensory-cognitive activation; physiological, hormonal, and subjective stress measurements were also performed. Results indicated that (a) "whole-brain" CBF increased during activation; (b) the greatest increase in CBF was in the primary visual cortex; (c) differences between hemispheres were not observed, but CBF was greater anteriorly than posteriorly in the deprivation condition only; (d) within-subject variability of CBF was not influenced by the sensory-cognitive condition; and (e) the procedure was not stressful.
Cameron
O G
OG
Department of Psychiatry, University of Michigan Medical Center, Ann Arbor 48109-0722.
Modell
J G
JG
Hichwa
R D
RD
Agranoff
B W
BW
Koeppe
R A
RA
D000328:Adult; D001794:Blood Pressure; D002395:Catecholamines / Q000097:blood; D002560:Cerebrovascular Circulation / Q000502:physiology*; D003071:Cognition / Q000502:physiology*; D006801:Humans; D008297:Male; D012677:Sensation / Q000502:physiology*; D013223:Statistics as Topic; D014793:Visual Cortex / Q000098:blood supply
D002395:Catecholamines