title: An open study of the efficacy and safety of single dose fosfomycin trometamol in treatment of hospitalised patients with urinary tract infection (pilot study).
abstract: Single dose fosfomycin trometamol (3 g) was used to treat 20 hospitalised patients with UTI. Tolerance was good or excellent in 19/20 patients; a satisfactory bacteriological outcome was recorded in 11/17 of patients with sensitive organisms and a satisfactory clinical outcome was noted in 12/16 symptomatic individuals.
authors.affiliation: Department of Medical Microbiology, Southmead Hospital, Bristol, United Kingdom.
authors.forename: A P
authors.initials: AP
authors.lastname: MacGowan
authors.forename: R A
authors.initials: RA
authors.lastname: Bailey
authors.forename: W
authors.initials: W
authors.lastname: Egner
authors.forename: D M
authors.initials: DM
authors.lastname: Picken
authors.forename: D S
authors.initials: DS
authors.lastname: Reeves
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000369:Aged, 80 and over; D004361:Drug Tolerance; D004926:Escherichia coli / Q000187:drug effects; D005260:Female; D005578:Fosfomycin / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D012074:Remission Induction; D013997:Time Factors; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D005578:Fosfomycin