Drug molecules of marine origin.
Somewhat accelerated developments in the chemistry and pharmacology of marine molecules during the eighties are a clear indication of the biomedical potential of marine organisms for the twenty-first century. Unfortunately, the overall effort toward the field is still insignificant. Both industry and governments are spending only a token share of R&D funds in pursuit of pharmacologically active substances from the sea. A critical appraisal of the literature reveals the existence of fascinating molecules with unusual and potent activities. The challenge of harnessing the clinical potential of these molecules is clearly evident. It is only awaiting the awakening of the academic, industrial, and federal researchers and resources. Only a concerted and a massive effort can shorten the time between now and the first clinical drug from the sea.
Kaul
P N
PN
Clark Atlanta University, Georgia 30314.
D000818:Animals; D000959:Antihypertensive Agents / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000737:chemistry*; D002317:Cardiovascular Agents / Q000737:chemistry*; D006801:Humans; D008387:Marine Toxins / Q000737:chemistry*; D015394:Molecular Structure
D000959:Antihypertensive Agents; D000970:Antineoplastic Agents; D002317:Cardiovascular Agents; D008387:Marine Toxins