title: Lesions and immune responses produced in hamsters and guinea pigs inoculated with some strains of leptospira.
abstract: Pathogenic lesions and immune responses in hamsters and guinea pigs produced by three leptospiral serovars, viz. autumnalis, grippotyphosa, and pomona, and their pool were experimentally studied. Hepatic lesions precede renal localisation. The infections were documented by the demonstration of leptospires and histopathological study. The 2-Me sensitive IgM was responsible for MAT titres in the early immune response.
authors.affiliation: Department of Preventive Medicine and Microbiology, Madras Veterinary College, India.
authors.forename: K
authors.initials: K
authors.lastname: Venugopal
authors.forename: S
authors.initials: S
authors.lastname: Ratnam
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis; D001428:Bacterial Vaccines / Q000276:immunology*; D006224:Cricetinae; D005260:Female; D006168:Guinea Pigs; D007668:Kidney / Q000473:pathology; D007919:Leptospira / Q000276:immunology* / Q000472:pathogenicity; D008099:Liver / Q000473:pathology; D008297:Male; D014774:Virulence
chemical_list: D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines