[Mutagenicity testing of some azo dyes used as food additives].
The mutagenicity of 4 azo dyes (Ponceau 4R, Amaranth, Sunset Yellow FCF and Tartrazine) that are widely used to color food has been evaluated. They were tested for mutagenicity in the Salmonella typhimurium plate-incorporation and preincubation assays. The standard plate-incorporation and preincubation assays performed directly on the dyes in the absence and presence of rat-liver S9. No mutagenic activity was seen for any of the azo dyes tested by using the standard tester strains, TA 98 and TA 100.
Izbirak
A
A
Hacettepe Universitesi, Fen Fakültesi, Biyoloji Bölümü, Moleküler Biyoloji Anabilim Dah.
Sümer
S
S
Diril
N
N
D000548:Amaranth Dye / Q000633:toxicity; D001391:Azo Compounds / Q000633:toxicity*; D005505:Food Coloring Agents / Q000633:toxicity*; D009152:Mutagenicity Tests; D009282:Naphthalenesulfonates; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics; D013645:Tartrazine / Q000633:toxicity
D001391:Azo Compounds; D005505:Food Coloring Agents; D009282:Naphthalenesulfonates; D000548:Amaranth Dye; C005842:6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt; D013645:Tartrazine; C576297:ponceau 4R
Gidalara katilan bazi azo boyalarinin mutajenik etkilerinin test edilmesi.