[Hypocalcemia after total thyroidectomy. Therapeutic considerations].
One of the post-operative complications of total thyroidectomy is the onset of a transitory or permanent hypocalcemic syndrome. Hypocalcemia is caused by different physiopathological mechanisms that operate either individually or in association (parathyroidal deficit, deficiency of bone calcium subsequent to parathyroid osteodystrophy, acute emission of calcitonin into the circulation). Calcemia levels were studied p.o. in a selected group of 25 patients who had undergone total extracapsular thyroidectomy with the apparent preservation of the parathyroid glands. Totals thyroidectomy has been performed in 15 patients with euthyroid goitre, in 4 with papillary carcinoma, in 3 with diffuse toxic goitre and in 3 with multinodular toxic goitre. Eight patients received drug and diet therapy since calcemia levels were lower than 7.5 mg/ml. Fifteen days after the operation, calcemia levels in 21 patients were subliminal and dihydrotachysterol therapy was commenced. Hypocalcemia was permanent in only one case.
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Istituto di Patologia Chirurgica III, Università degli Studi di Catania.
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D002118:Calcium / Q000097:blood; D004097:Dihydrotachysterol / Q000627:therapeutic use; D006801:Humans; D006996:Hypocalcemia / Q000188:drug therapy / Q000209:etiology*; D013577:Syndrome; D013965:Thyroidectomy / Q000009:adverse effects*
D004097:Dihydrotachysterol; D002118:Calcium
La ipocalcemia post-tiroidectomia totale. Considerazioni terapeutiche.