[Fluorophotometry of the vitreous body in diabetics without retinopathy or with minimal retinopathy].
Vitreous fluorophotometry using the Fluorotron Master, was performed on the two eyes of 56 diabetics patients 45,65 year-old +/- 14,91 (mean +/- S.D.), duration of diabetes was 15,14 years +/- 9,17; and on one eye of 17 normal subjects 39,18 years old +/- 11,19. According to biomicroscopic and angiographic examinations, only diabetic subjects with either no or microaneurysmal retinopathy were included. Three groups of right and three groups of left eyes were made: Groups 1: no retinopathy (28 right eyes, 27 left eyes); Groups 2: 1 to 5 microaneurysms (11 right eyes, 20 left eyes); Groups 3: greater than 5 microaneurysms (11 right eyes, 9 left eyes) For the two eyes, posterior vitreous penetration ratio increased with the degree of retinopathy. In the eyes without retinopathy (Groups 1), the penetration ration is not statistically different from the normal subjects; it was the opposite for the eyes with microaneurysmal retinopathy (Groups 2 et 3). The results indicated a breakdown of the blood-retinal barrier only when clinical diabetic retinopathy was present. The relation between fluorophotometric evaluation and the degree of retinopathy showed that vitreous fluorophotometry can be useful in the follow-up of diabetic subjects.
Bordat
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B
CHRU Hôpital Gui de Chauliac, Service d'Ophthalmologie, Montpellier.
Guirgis
I R
IR
Manderscheid
J C
JC
D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001813:Blood-Retinal Barrier; D003920:Diabetes Mellitus / Q000503:physiopathology*; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology; D003930:Diabetic Retinopathy / Q000503:physiopathology; D005260:Female; D015590:Fluorophotometry; D006801:Humans; D008297:Male; D008875:Middle Aged
Fluorophotométrie du vitré chez les diabétiques avec rétinopathie absente ou minime.