Orchidectomy alone for stage I seminoma of the testis.
Between 1983 and 1988, 113 patients with Stage I seminoma were managed after orchidectomy by surveillance rather than adjuvant radiotherapy. The actuarial risk of relapse at 3 years was 15.8% (95% confidence interval, 7.8% to 23.8%). All 13 patients who experienced a relapse are currently in remission (4 to 45 months after salvage therapy), although 5 suffered second relapses requiring further treatment. Close surveillance is a safe alternative to adjuvant radiotherapy in Stage I seminoma. However, the policy requires prolonged observation of patients with intensive use of resources. Therefore, adjuvant radiotherapy should be considered the treatment of choice.
Duchesne
G M
GM
Testicular Tumour Unit, Royal Marsden Hospital, Surrey, United Kingdom.
Horwich
A
A
Dearnaley
D P
DP
Nicholls
J
J
Jay
G
G
Peckham
M J
MJ
Hendry
W F
WF
D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D004407:Dysgerminoma / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009919:Orchiectomy; D012008:Recurrence; D012074:Remission Induction; D012086:Reoperation; D013736:Testicular Neoplasms / Q000473:pathology / Q000601:surgery*