title: Adnexal torsion of hyperstimulated ovaries in pregnancies after gonadotropin therapy.
abstract: A series of 201 cycles of ovarian hyperstimulation syndrome (OHSS) in 154 women were reviewed. Pregnancy occurred in 75 of 201 cycles. Twelve pregnant women (16%) presented with torsion of hyperstimulated ovary, but only 3 out of 126 patients (2.3%) who did not conceive had torsion. Because diagnosis of adnexal torsion is usually uncertain and surgical intervention is likely to be delayed, these infertile women risk losing their ovaries. The clinical picture of torsion of adnexa in patients with OHSS is presented here. The combination of ovarian enlargement, abdominal pain, nausea, progressive leukocytosis, and anemias might indicate torsion of adnexa. Although during operation the adnexa appears dark, hemorrhagic and ischemic, we suggest that it can be saved by simply unwinding it. In 11 such cases intraoperative unwinding of the adnexa was performed, and in 8 patients it was the only operative procedure. No postoperative complications were noted and in all the cases the ovaries were proven functional by ultrasonography. We concluded that torsion of hyperstimulated adnexa in patients who conceived after gonadotropin therapy, is a special entity that requires more attention to achieve early diagnosis. Nevertheless even with delayed diagnosis, the ovary can still be saved.
authors.affiliation: Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
authors.forename: S
authors.initials: S
authors.lastname: Mashiach
authors.forename: D
authors.initials: D
authors.lastname: Bider
authors.forename: O
authors.initials: O
authors.lastname: Moran
authors.forename: M
authors.initials: M
authors.lastname: Goldenberg
authors.forename: Z
authors.initials: Z
authors.lastname: Ben-Rafael
mesh_terms: D000291:Adnexal Diseases / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D006063:Chorionic Gonadotropin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D010049:Ovarian Diseases / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D010053:Ovary / Q000187:drug effects* / Q000473:pathology / Q000503:physiopathology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D011256:Pregnancy Outcome; D014102:Torsion Abnormality
chemical_list: D006063:Chorionic Gonadotropin