title: Spect bone scintigraphy in assessment of cranial Paget's disease.
abstract: Single photon emission computed tomography (SPECT) bone scintigraphy was used in the assessment of Paget's disease in 3 patients with skull involvement. In comparison with conventional scintigraphy, SPECT improved the three-dimensional perception and made precise outlining of involved bones possible. The radionuclide uptake in lesions expressed as counts per pixel was 1.5 to 10 times that of normal bones. Routine use of SPECT in cranial Paget's disease for staging and monitoring the effect of treatment is proposed.
authors.affiliation: Department of Clinical Physiology, Aarhus Municipal Hospital, Denmark.
authors.forename: K
authors.initials: K
authors.lastname: Brixen
authors.forename: H H
authors.initials: HH
authors.lastname: Hansen
authors.forename: L
authors.initials: L
authors.lastname: Mosekilde
authors.forename: H
authors.initials: H
authors.lastname: Halaburt
mesh_terms: D000368:Aged; D004164:Diphosphonates; D005260:Female; D006801:Humans; D008297:Male; D015609:Organotechnetium Compounds; D010001:Osteitis Deformans / Q000000981:diagnostic imaging*; D012886:Skull / Q000000981:diagnostic imaging*; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D004164:Diphosphonates; D015609:Organotechnetium Compounds; C033905:technetium Tc 99m 1,1-diphosphonopropane-2,3-dicarboxylic acid