Esophageal prostaglandins in guinea pigs and rats.
The synthesis of prostaglandins (PGs) in the mucosa of the esophagus is studied in 20 albinotic adult guinea pigs and rats using the radioimmunoassay method. Both species investigated synthesize five PGs. The PG synthesis activity in the guinea pig's esophagus is higher than that in the rat's. PGE2 and PGF2 alpha might be involved in the regulation of lower esophagus sphincter pressure.
Aharinejad
S
S
1st Department of Anatomy, University of Vienna, Austria.
Franz
P
P
Sinzinger
H
H
Firbas
W
W
D015121:6-Ketoprostaglandin F1 alpha / Q000032:analysis / Q000378:metabolism / Q000502:physiology; D000818:Animals; D015232:Dinoprostone / Q000032:analysis / Q000378:metabolism / Q000502:physiology; D004947:Esophagus / Q000737:chemistry* / Q000378:metabolism / Q000502:physiology; D005260:Female; D006168:Guinea Pigs; D008297:Male; D015230:Prostaglandin D2 / Q000032:analysis / Q000378:metabolism / Q000502:physiology; D011453:Prostaglandins / Q000032:analysis* / Q000378:metabolism / Q000502:physiology; D011863:Radioimmunoassay; D051381:Rats; D013929:Thromboxane B2 / Q000032:analysis / Q000378:metabolism / Q000502:physiology
D011453:Prostaglandins; D013929:Thromboxane B2; D015121:6-Ketoprostaglandin F1 alpha; D015232:Dinoprostone; D015230:Prostaglandin D2