title: [Energy metabolism in the kidneys after hypokinesia of varying duration].
abstract: This paper presents data suggesting that tissue homogenates can be used to assess mitochondrial oxidation. The effect of hypokinesia of various duration on tissue respiration and oxidative phosphorylation of rat kidneys was investigated for the first time. It was found that 3-day hypokinesia led to a decrease of tissue respiration due to a lower contribution of endogenous fatty acids; 10-day hypokinesia caused activation of tissue respiration on endogenous and exogenous pyridine and flavoprotein-dependent substrates; 30-, 70- and 140-day hypokinesia brought about changes in energy formation at the expense of inhibition of respiratory activity of preparations and uncoupling of oxidative phosphorylation. Mechanisms of the above disturbances in energy metabolism reactions of kidneys are discussed.
authors.forename: A I
authors.initials: AI
authors.lastname: Gritsuk
authors.forename: N A
authors.initials: NA
authors.lastname: Glotov
authors.forename: I G
authors.initials: IG
authors.lastname: Danilova
authors.forename: N K
authors.initials: NK
authors.lastname: Segal'
mesh_terms: D000818:Animals; D004734:Energy Metabolism / Q000502:physiology*; D007103:Immobilization / Q000502:physiology*; D007668:Kidney / Q000378:metabolism*; D008297:Male; D008928:Mitochondria / Q000378:metabolism*; D008954:Models, Biological; D010085:Oxidative Phosphorylation; D010101:Oxygen Consumption / Q000502:physiology; D051381:Rats; D013997:Time Factors
vernacular_title: Energeticheskiĭ obmen v pochkakh pri deĭstvii na organizm gipokinezii razlichnoĭ dlitel'nosti.