title: The viability of articular cartilage in fresh osteochondral allografts after clinical transplantation.
abstract: The articular cartilage of four fresh osteochondral allografts was biopsied after transplantation, and its viability was studied by autoradiography. The biopsy specimens were labeled with both 3H-cytidine, for newly synthesized ribonucleic acid, and 35S-sulphate, for newly synthesized proteoglycans. The cartilage of a lateral humeral condylar graft at twelve months had 96 to 99 per cent labeled chondrocytes, the articular cartilage of a medial femoral condylar graft at twenty-four months showed 69 to 78 per cent labeled chondrocytes, and the cartilage of a medial tibial-plateau graft at forty-one months had 90 per cent labeled cells. At six years, a lateral tibial-plateau graft had 37 per cent labeled chondrocytes.
authors.affiliation: Department of Surgery, University of Toronto, Ontario, Canada.
authors.forename: A A
authors.initials: AA
authors.lastname: Czitrom
authors.forename: S
authors.initials: S
authors.lastname: Keating
authors.forename: A E
authors.initials: AE
authors.lastname: Gross
mesh_terms: D000328:Adult; D001345:Autoradiography; D002358:Cartilage, Articular / Q000473:pathology / Q000637:transplantation*; D002470:Cell Survival; D003562:Cytidine; D004551:Elbow Joint / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D006085:Graft Survival; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D013431:Sulfates; D013997:Time Factors
chemical_list: D013431:Sulfates; D003562:Cytidine