Malignant carcinoid syndrome. Failure of anti-oestrogenic therapy.
A pre-menopausal patient with a six-year history of symptoms of the metastatic carcinoid syndrome leading to progressively worsening carcinoid heart disease is described. The failure of anti-oestrogenic therapy (sequential bilateral oophorectomy and Tamoxifen therapy) to halt progression of disease was documented. Death resulted from right ventricular failure associated with pulmonary and tricuspid valvular disease.
Ramcharan
K
K
San Fernando General Hospital, Trinidad.
Pooransingh
C
C
Harnarayan
C
C
Shah-Parsad
M
M
McFarlane
H
H
D001706:Biopsy; D005260:Female; D006801:Humans; D008303:Malignant Carcinoid Syndrome / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D008875:Middle Aged; D013629:Tamoxifen / Q000008:administration & dosage / Q000627:therapeutic use*
D013629:Tamoxifen