title: A questionnaire investigation of anxiety and depression in early dementia.
abstract: We report findings on a study of anxiety and depression by questionnaire in 50 patients with mild dementia and 134 control subjects using the Hospital Anxiety and Depression Scale. Thirty-eight percent of patients and 9% of controls had a possible or probable diagnosis of an anxiety disorder. Possible or probable depression was found in 28% of the patients and 3% of the controls. These rates for the patients were above those in normal populations. All patients and control subjects were tested with the Extended Scale for Dementia (ESD). Neither group showed a significant relationship between depression and ESD scores. In the control subjects there was a negative correlation (P less than .006) between anxiety and cognitive scores, one that was not found in the patients.
authors.affiliation: Department of Research, London Psychiatric Hospital, Ontario, Canada.
authors.forename: K
authors.initials: K
authors.lastname: Wands
authors.forename: H
authors.initials: H
authors.lastname: Merskey
authors.forename: V C
authors.initials: VC
authors.lastname: Hachinski
authors.forename: M
authors.initials: M
authors.lastname: Fisman
authors.forename: H
authors.initials: H
authors.lastname: Fox
authors.forename: M
authors.initials: M
authors.lastname: Boniferro
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001008:Anxiety Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D003704:Dementia / Q000150:complications*; D003866:Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D006778:Hospitals, Psychiatric; D006785:Hospitals, University; D006801:Humans; D008297:Male; D008875:Middle Aged; D009864:Ontario; D015995:Prevalence; D011569:Psychiatric Status Rating Scales; D011795:Surveys and Questionnaires