Morning glory syndrome: a histopathological study.
The clinical and histopathological findings in a case of morning glory syndrome are described. Axial optic nerve retrodisplacement into a peripapillary scleral ectasia (staphyloma), absence of fibrous lamina cribrosa, and optic nerve atrophy were associated with various other, non-inherent ocular developmental anomalies. The uninterrupted lining of the inner wall of the staphyloma by one-layered, normal retinal pigment epithelium proves that the syndrome is not due to a neuroectodermal closure defect.
Manschot
W A
WA
Institute of Pathology, Erasmus University, Rotterdam, The Netherlands.
D000869:Anterior Eye Segment / Q000473:pathology*; D005124:Eye Abnormalities / Q000473:pathology*; D006801:Humans; D007223:Infant; D008297:Male; D009900:Optic Nerve / Q000002:abnormalities; D012590:Sclera / Q000002:abnormalities; D013577:Syndrome