Age-incidence artifacts do not account for the season-of-birth effect in schizophrenia.
Contrary to the position taken by Lewis (1989), several articles have demonstrated an association between season of birth and the risk of schizophrenia after controlling for the age-incidence effect. The method used by Pulver et al. (1983) was misinterpreted by Lewis. Clarification of this method is provided along with additional references related to the season-of-birth issue.
Pulver
A E
AE
Epidemilogy/Genetics Program, Johns Hopkins University School of Medicine, Baltimore, MD 21203.
Moorman
C C
CC
Brown
C H
CH
McGrath
J A
JA
Wolyniec
P S
PS
D000328:Adult; D000367:Age Factors; D000368:Aged; D015982:Bias; D003430:Cross-Sectional Studies; D006801:Humans; D015994:Incidence; D015993:Life Tables; D008875:Middle Aged; D012307:Risk Factors; D012559:Schizophrenia / Q000453:epidemiology / Q000209:etiology*; D012565:Schizophrenic Psychology; D012621:Seasons