Magnetic field exposure from electric appliances and childhood cancer.
The effect on childhood cancer of prolonged exposure to 60-H magnetic fields from electric appliances was examined using interview data from a recently completed case-control study. Exposures of children aged 0-14 years whose incident cancers were diagnosed between 1976 and 1983 and who resided in the Denver, Colorado, Standard Metropolitan Statistical Area were compared with those of controls selected by random digit dialing, matched on age, sex, and telephone exchange area. Parents of 252 cases and 222 controls were interviewed at home about the use of electric appliances by the mother during pregnancy (prenatal exposure) and by the child (postnatal exposure). After adjustment for income, prenatal electric blanket exposure was associated with a small increase in the incidence of childhood cancers (odds ratio (OR) = 1.3, 95% confidence interval (CI) 0.7-2.2) that was more pronounced for leukemia (OR = 1.7, 95% CI 0.8-3.6) and brain cancer (OR = 2.5, 95% CI 1.1-5.5). Postnatal exposure to electric blankets was also weakly associated with childhood cancer (OR = 1.5, 95% CI 0.6-3.4), with a larger but imprecise association with acute lymphocytic leukemia (OR = 1.9, 95% CI 0.6-6.5). Water beds and bedside electric clocks were unrelated to childhood cancer incidence. Results are limited by nonresponse and imprecision resulting from the rarity of appliance use, especially for subgroups of cases. Nonetheless, electric blankets, one of the principal sources of prolonged magnetic field exposure, were weakly associated with childhood cancer and warrant a more thorough evaluation.
Savitz
D A
DA
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill 27599.
John
E M
EM
Kleckner
R C
RC
D000293:Adolescent; D001512:Bedding and Linens; D001932:Brain Neoplasms / Q000453:epidemiology / Q000209:etiology*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D003120:Colorado; D004574:Electromagnetic Fields; D055590:Electromagnetic Phenomena; D004781:Environmental Exposure; D004869:Equipment Safety; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007938:Leukemia / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011897:Random Allocation; D012307:Risk Factors; D013997:Time Factors