title: [Gadolinium-DTPA in the study of intracranial tumors in the adult].
abstract: Thirty intracranial tumours were explored by MRI, using T1- and T2-weighted sequences, before and after intravenous injection of Gd-DTPA. Two-thirds of the intra-axial tumours were accurately detected on one section plane by MRI without Gd-DTPA, but in one quarter of the cases Gd-DTPA only delineated precisely the tumour. On the other hand, Gd-DTPA failed to detect certain tumours (benign gliomas) or showed only a small part of them (mixed grade gliomas), while they were detected by MRI without contrast injection. However, in such cases Gd-DTPA was useful for the stereotaxic biopsy of the tumour. Gd-DTPA appears of lesser interest in extra-axial tumours. Gd-DTPA is thus valuable for the neuroradiological diagnosis of brain tumours, particularly to evaluate the grade of gliomas and to confirm the diagnosis of recurrent growths.
authors.affiliation: Service de Neuroradiologie Clinique et Experimentale CHU, La Timone, Marseille.
authors.forename: N
authors.initials: N
authors.lastname: Grégoire
authors.forename: T
authors.initials: T
authors.lastname: Momose
authors.forename: C
authors.initials: C
authors.lastname: Rumeau
authors.forename: S
authors.initials: S
authors.lastname: Perot
authors.forename: N
authors.initials: N
authors.lastname: Girard
authors.forename: A
authors.initials: A
authors.lastname: Lavanga
authors.forename: G
authors.initials: G
authors.lastname: Salamon
mesh_terms: D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000601:surgery; D002493:Central Nervous System Diseases / Q000175:diagnosis / Q000473:pathology; D005260:Female; D019786:Gadolinium DTPA; D005910:Glioma / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D009942:Organometallic Compounds; D004369:Pentetic Acid
chemical_list: D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA
vernacular_title: Apport du gadolinium-DTPA à l'étude des tumeurs intracrâniennes de l'adulte.