[The characteristics of the temporal dynamics of stereotypic behavior in rats during chronic fenamine administration].
Amphetamine-induced stereotyped behavior is a nonsteady oscillatory process. In its structure waves with 2-3, 4-5 and 10-15 minute periods may be distinguished. In some animals (30%) after chronic amphetamine administration the stereotyped behavior was attenuated with reorganization of its rhythmical pattern but in other cases (35%) stereotype on the contrary increased. Tolerance developed in the animals which had initially the more pronounced stereotype with the predomination of short-period (2-3 min) waves on the chronogram. These animals demonstrated low locomotor activity in the opened field, greater immobility in the forced swimming test and better relearning in Y-maze.
Arushanian
E B
EB
Popov
A V
AV
D000661:Amphetamine / Q000494:pharmacology*; D000818:Animals; D001332:Automatism / Q000139:chemically induced / Q000503:physiopathology; D004361:Drug Tolerance; D008297:Male; D051381:Rats; D011916:Rats, Inbred F344; D013239:Stereotyped Behavior / Q000187:drug effects* / Q000502:physiology; D013997:Time Factors
D000661:Amphetamine
Osobennosti vremennóĭ dinamiki stereotipnogo povedeniia krys pri khronicheskom vvedenii fenamina.