Schizophrenic individuals with bipolar first-degree relatives: analysis of two pedigrees.
During the course of a family-interview study of probands with psychotic disorders, the authors encountered two pedigrees in which schizophrenic individuals had first-degree relatives with bipolar disorder. The authors describe the members of both families in detail and discuss several hypotheses that might account for the co-occurrence of schizophrenia and bipolar disorder in the same family.
Pope
H G
HG
Laboratories for Psychiatric Research, McLean Hospital, Belmont, Mass. 02178.
Yurgelun-Todd
D
D
D000293:Adolescent; D000328:Adult; D001714:Bipolar Disorder / Q000150:complications / Q000175:diagnosis / Q000235:genetics*; D003951:Diagnostic Errors; D005190:Family; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors; D012559:Schizophrenia / Q000150:complications / Q000175:diagnosis / Q000235:genetics*; D012565:Schizophrenic Psychology; D012737:Sex Factors