title: The use of intravenous streptokinase (SK) in a peripheral hospital in the treatment of acute myocardial infarction.
abstract: We report our early experience in the use of intravenous Streptokinase in acute coronary occlusion in a peripheral hospital. From 1st November 1988 to 20th July 1989, 30 patients were treated with Streptokinase. The hospital mortality was 1/30 (3.3%) from a non-streptokinase related event. The commonest complication following streptokinase infusion was transient hypotension, affecting 10/30 patients. From a total of 30 patients, 3 had transient bleeding complications and was self limiting. Follow up coronary angiograms were performed on 17/30 patients, demonstrating a patent infarct related artery in 12/17 patients (70.6%). We concluded that it is both feasible and safe to use intravenous streptokinase in a peripheral setting in the treatment of acute myocardial infarction.
authors.affiliation: Department of Medicine, Alexandra Hospital, Singapore.
authors.forename: G
authors.initials: G
authors.lastname: Chia
authors.forename: N S
authors.initials: NS
authors.lastname: Chan
authors.forename: P K
authors.initials: PK
authors.lastname: Mah
authors.forename: L S
authors.initials: LS
authors.lastname: Chew
authors.forename: A T
authors.initials: AT
authors.lastname: Tan
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000628:therapy; D006781:Hospitals, Satellite; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality / Q000628:therapy*; D012770:Shock, Cardiogenic / Q000628:therapy; D012846:Singapore / Q000453:epidemiology; D013300:Streptokinase / Q000008:administration & dosage*; D015996:Survival Rate
chemical_list: D013300:Streptokinase