title: Role of intraoperative prograde colonic lavage and a decompressive loop ileostomy in the management of transmural amoebic colitis.
abstract: A prospective analysis is presented of a selected group of 45 consecutive patients with transmural amoebic colitis treated by laparotomy, colonic lavage and ileostomy (phase 1 surgery) over 3 years. The diagnosis of amoebic colitis and amoebic perforation of the bowel were difficult and therefore all patients with 'acute abdomen' had proctosigmoidoscopy and a trial of metronidazole for 24-48 h before laparotomy. At laparotomy, adhesive wraps were present in all patients; 13 perforations were exposed by inadvertent disturbance of adhesive wraps but were successfully closed by suture to any available organ in close proximity, such as the omentum or small bowel. Four patients (9 per cent) died after phase 1 surgery. After 6 weeks when the acute disease had healed, 33 of the remaining 41 patients (80 per cent) required closure of ileostomy only, five had resection of stricture and three (7 per cent) needed stricturoplasty (phase 2 surgery). Two patients (5 per cent) died after phase 2 surgery. Thus, in surgery for transmural amoebic colitis adhesive wraps should not be disturbed as they mechanically protect the peritoneal cavity from faecal soiling when perforation occurs. The colon should be emptied by lavage and the faecal stream diverted to avoid secondary bacterial effects.
authors.affiliation: Department of Surgery, University of Natal, Faculty of Medicine, Congella, South Africa.
authors.forename: F M
authors.initials: FM
authors.lastname: Luvuno
mesh_terms: D000328:Adult; D000368:Aged; D003106:Colon; D004404:Dysentery, Amebic / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D007081:Ileostomy; D007432:Intraoperative Period; D007813:Laparotomy; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology; D011446:Prospective Studies; D007507:Therapeutic Irrigation; D000267:Tissue Adhesions / Q000601:surgery