title: Necrotizing perianal infection in children: report of two cases.
abstract: Two girls aged 1 9/12 years and 5 months were treated for necrotizing perianal infection. In both patients, the necrotizing ulcers around the anus developed following an episode of diarrhea. A poor nutritional status with low body weight (25th percentile) and hypoalbuminemia (2.5 g/L) in the elder patient, as well as a hypogammaglobulinemia in the younger one, may predispose them to bacterial infection and subsequent perianal lesions. Anorectal trauma was denied. The necrotizing infection was confined to the skin and the subcutaneous tissue layer, and both patients had a benign clinical course. We report it and briefly discuss the etiology and treatment of this rare disorder.
authors.affiliation: Department of Surgery, Chang Gung Memorial Hospital, Kaohsiung, Taiwan, Republic of China.
authors.forename: J H
authors.initials: JH
authors.lastname: Chuang
authors.forename: K S
authors.initials: KS
authors.lastname: Wong
mesh_terms: D001004:Anus Diseases / Q000209:etiology* / Q000628:therapy; D001424:Bacterial Infections / Q000209:etiology* / Q000628:therapy; D003968:Diarrhea, Infantile / Q000150:complications; D005260:Female; D006801:Humans; D007223:Infant; D009336:Necrosis / Q000209:etiology; D011349:Proctitis / Q000209:etiology* / Q000628:therapy