Chronic nicotine induces a specific appetite for sucrose in rats.
Thirty female albino rats were implanted with subcutaneous pellets releasing nicotine or amphetamine in order to study the effects of chronic pharmacological treatment on food intake and body weight. The pellets were removed after tolerance (a decrease in anorectic properties of the drugs) had developed. Nicotine administration produced a specific appetite for sucrose both during and following treatment (p less than 0.05).
Jias
L M
LM
University of California, Los Angeles 90024.
Ellison
G
G
D000661:Amphetamine / Q000494:pharmacology; D000818:Animals; D001066:Appetite / Q000187:drug effects*; D003314:Corn Oil; D004343:Drug Implants; D004361:Drug Tolerance; D005260:Female; D005518:Food Preferences / Q000187:drug effects*; D009538:Nicotine / Q000008:administration & dosage / Q000494:pharmacology*; D011897:Random Allocation; D051381:Rats; D013395:Sucrose
D004343:Drug Implants; D013395:Sucrose; D009538:Nicotine; D003314:Corn Oil; D000661:Amphetamine