title: Do the benefits of breastfeeding outweigh the risk of postnatal transmission of HIV via breastmilk?
abstract: Conflicting recommendations have been offered about whether HIV+ mothers should breastfeed. Since there is a strong precedent for US infant feeding practices to be imitated in developing countries, a model was constructed to estimate infant mortality if the CDC admonition for HIV+ mothers not to breastfeed were upheld in less developed settings. Estimates are given for infant mortality in the presence and absence of breastfeeding across several baseline levels of infant mortality and across several theoretical rates of transmission through breastfeeding. The infant mortality associated with HIV infection acquired through breastfeeding is estimated to be lower than the mortality associated with the diseases of infancy that would result if breastmilk were withheld. The difference in these estimates is greater in areas with high baseline levels of infant mortality.
authors.affiliation: Family Health International, Research Triangle Park Branch, Durham, NC 27709.
authors.forename: K I
authors.initials: KI
authors.lastname: Kennedy
authors.forename: J A
authors.initials: JA
authors.lastname: Fortney
authors.forename: M G
authors.initials: MG
authors.lastname: Bonhomme
authors.forename: M
authors.initials: M
authors.lastname: Potts
authors.forename: P
authors.initials: P
authors.lastname: Lamptey
authors.forename: W
authors.initials: W
authors.lastname: Carswell
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000401:mortality / Q000635:transmission*; D001903:Bottle Feeding; D001942:Breast Feeding; D003906:Developing Countries; D005260:Female; D006679:HIV Seropositivity; D006801:Humans; D007226:Infant Mortality; D012307:Risk Factors