title: C-reactive protein during normal pregnancy.
abstract: Serum C-reactive protein (CRP) is determined in a prospective longitudinal study of 60 low-risk pregnant women. CRP is also measured in umbilical-cord blood after delivery. The serum CRP concentrations seem to be independent of pregnancy and gestational age. The 95th percentile is estimated to be 20 mg/l, and this value is considered as the upper limit of normal. A rise in CRP level is considered more predictive of infection than a determination of a single high value. CRP does not cross the placental barrier, and may therefore be useful in diagnosing infections in newborns.
authors.affiliation: Department of Obstetrics and Gynecology, Sct Maria Hospital, Vejle, Denmark.
authors.forename: F R
authors.initials: FR
authors.lastname: Nielsen
authors.forename: K M
authors.initials: KM
authors.lastname: Bek
authors.forename: P E
authors.initials: PE
authors.lastname: Rasmussen
authors.forename: I
authors.initials: I
authors.lastname: Qvist
authors.forename: M
authors.initials: M
authors.lastname: Tobiassen
mesh_terms: D002097:C-Reactive Protein / Q000378:metabolism*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis; D007239:Infections / Q000175:diagnosis; D008137:Longitudinal Studies; D011237:Predictive Value of Tests; D011247:Pregnancy / Q000097:blood*; D011446:Prospective Studies; D012016:Reference Values
chemical_list: D002097:C-Reactive Protein