title: Tc-99m HMPAO SPECT of the brain in the neonate.
abstract: A brain scan with Tc-99m hexamethylpropyleneamineoxime (HMPAO) performed on a neonate demonstrated normal localization only in the sensorimotor cortex, basal ganglia, and cerebellum. This pattern of localization is remarkably similar to previously published PET images of the neonate. Because Tc-99m HMPAO is readily available and has biochemical and physical characteristics that are suitable for perfusion imaging of the brain, it likely will become a major imaging agent in nuclear medicine. Normal scan findings in the neonatal age group with Tc-99m HMPAO have not been previously reported because of limited clinical use to date.
authors.affiliation: Department of Diagnostic Radiology, University of Kentucky Medical Center, Lexington 40536-0084.
authors.forename: D S
authors.initials: DS
authors.lastname: Fockele
authors.forename: R J
authors.initials: RJ
authors.lastname: Baumann
authors.forename: W J
authors.initials: WJ
authors.lastname: Shih
authors.forename: U Y
authors.initials: UY
authors.lastname: Ryo
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging*; D005260:Female; D005311:Fetal Hypoxia / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D015609:Organotechnetium Compounds; D010091:Oximes; D011247:Pregnancy; D011877:Radionuclide Imaging; D012016:Reference Values; D019690:Technetium Tc 99m Exametazime
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime