title: Plasma 3-methoxy-4-hydroxyphenylglycol in manic patients: relationships with clinical variables.
abstract: Plasma levels of 3-methoxy-4-hydroxyphenylglycol (MHPG) were found to be significantly higher in manic patients than in age- and sex-matched normal controls (n = 22). In 18 manic patients plasma MHPG correlated with manic symptoms but not with anxiety, depression, motor behaviour, acute psychosis, schizophrenia and severity of illness. A positive correlation between MHPG and grandiosity items on rating scales suggests a link with cognitive contents and therefore a relationship with central factors.
authors.affiliation: Department of Psychiatry, Timone Hospital, Marseille, France.
authors.forename: J M
authors.initials: JM
authors.lastname: Azorin
authors.forename: G
authors.initials: G
authors.lastname: Pupeschi
authors.forename: M
authors.initials: M
authors.lastname: Valli
authors.forename: P
authors.initials: P
authors.lastname: Joanny
authors.forename: D
authors.initials: D
authors.lastname: Raucoules
authors.forename: C
authors.initials: C
authors.lastname: Lancon
authors.forename: R
authors.initials: R
authors.lastname: Tissot
mesh_terms: D000293:Adolescent; D000328:Adult; D001714:Bipolar Disorder / Q000097:blood*; D003071:Cognition / Q000502:physiology; D005260:Female; D006018:Glycols / Q000097:blood*; D006801:Humans; D008297:Male; D008734:Methoxyhydroxyphenylglycol / Q000097:blood*; D008875:Middle Aged
chemical_list: D006018:Glycols; D008734:Methoxyhydroxyphenylglycol