title: [Determination of cerebral blood flow using an 81Rb/81mKr generator system].
abstract: A method is being developed which not only measures cerebral blood flow as a static quantity but also its changes with time. For that purpose a semiconductor device ascertains the proportion of intracerebral 81 Rb and 81mKr activities. By opening the hemato-encephalic barrier in animal experiments a sufficient concentration of intracerebral 81 Rb could be attained and the modified blood circulation after step-wise ligature of all brain arteries brought into relation to the corresponding Rb/Kr quotient. Over the range from undisturbed to completely interrupted cerebral blood flow this quotient varied up to 25% of its initial value.
authors.affiliation: Abteilung für Nuklearmedizin und med. Physik der Med, Fakultät, Universitätsklinik des Saarlandes Homburg/Saar, Bundesrepublik Deutschland.
authors.forename: H J
authors.initials: HJ
authors.lastname: Schroth
authors.forename: J
authors.initials: J
authors.lastname: Bialy
authors.forename: F J
authors.initials: FJ
authors.lastname: Hans
authors.forename: E
authors.initials: E
authors.lastname: Oberhausen
authors.forename: J W
authors.initials: JW
authors.lastname: Peters
authors.forename: M
authors.initials: M
authors.lastname: Schmitt
authors.forename: P
authors.initials: P
authors.lastname: Warnke
mesh_terms: D000818:Animals; D001812:Blood-Brain Barrier; D002560:Cerebrovascular Circulation; D004285:Dogs; D007727:Krypton Radioisotopes; D009994:Osmolar Concentration; D011817:Rabbits; D011876:Radionuclide Generators; D012414:Rubidium Radioisotopes; D012996:Solutions
chemical_list: D007727:Krypton Radioisotopes; D012414:Rubidium Radioisotopes; D012996:Solutions
vernacular_title: Bestimmung des zerebralen Blutflusses mittels des 81Rb/81mKr-Generatorsystems.