title: Sex differences in the hyperkinetic syndrome of childhood.
abstract: Among a clinic sample of 6525 subjects, 61 males and 18 females with an ICD-9 diagnosis of the hyperkinetic syndrome of childhood were identified. Hyperactive girls had a lower IQ and significantly higher rates of language disorders and neurological disorders, suggesting a possible neurological basis for hyperactivity in females. In contrast, there was a population of male hyperactives with less evidence of brain dysfunction and a normal IQ, evidence compatible with the model of greater male constitutional variability. There was little evidence for the polygenetic multiple threshold model of sex inheritance.
authors.affiliation: Highfield Family and Adolescent Unit, Warneford Hospital, Oxford, U.K.
authors.forename: A
authors.initials: A
authors.lastname: James
authors.forename: E
authors.initials: E
authors.lastname: Taylor
mesh_terms: D002648:Child; D002653:Child Behavior Disorders / Q000453:epidemiology* / Q000523:psychology; D005260:Female; D006801:Humans; D006948:Hyperkinesis / Q000453:epidemiology* / Q000523:psychology; D007361:Intelligence Tests; D008297:Male; D019965:Neurocognitive Disorders / Q000523:psychology; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors