Cis-platinum combination chemotherapy during pregnancy for advanced epithelial ovarian carcinoma.
Epithelial carcinoma of the ovary, a rare complication of pregnancy, was diagnosed at 16 weeks' gestation after presentation as an acute abdomen. Exploration with conservative surgery was done, and cis-platinum-based combination chemotherapy was administered for the remainder of the pregnancy. Induction and vaginal delivery resulted in a successful outcome for mother and fetus. Postpartum laparotomy was negative.
Malfetano
J H
JH
Department of Obstetrics and Gynecology, Albany Medical Center, New York.
Goldkrand
J W
JW
D000328:Adult; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D003520:Cyclophosphamide / Q000008:administration & dosage; D003536:Cystadenocarcinoma / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000188:drug therapy*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis / Q000188:drug therapy*
D015295:Antigens, Tumor-Associated, Carbohydrate; D003520:Cyclophosphamide; D002945:Cisplatin