title: [Treatment of secretory otitis media].
abstract: Blood serum of 38 patients with otitis media (14 men and 24 women), aged 16 to 55 years, was examined immunologically. The patients were subdivided into two groups that received identical traditional therapy. However the Group 2 patients were also given per os 0.5 g sodium nucleinate 3 times a day for 10 days. Before and after treatment all the patients underwent immunological tests which included measurements of T- and B-lymphocytes, T-helpers and T-suppressors as well as immunoglobulins M, A, G and complement. It was demonstrated that sodium nucleinate exerted beneficial clinical and immunological effects.
authors.forename: S A
authors.initials: SA
authors.lastname: Iarlykov
authors.forename: A M
authors.initials: AM
authors.lastname: Zemskov
authors.forename: S D
authors.initials: SD
authors.lastname: Poliakova
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000293:Adolescent; D000328:Adult; D003165:Complement System Proteins / Q000032:analysis; D004322:Drainage; D004432:Ear, Middle / Q000601:surgery; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007958:Leukocyte Count; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009696:Nucleic Acids / Q000627:therapeutic use; D010034:Otitis Media with Effusion / Q000188:drug therapy / Q000276:immunology / Q000628:therapy*; D013997:Time Factors
chemical_list: D000276:Adjuvants, Immunologic; D007136:Immunoglobulins; D009696:Nucleic Acids; D003165:Complement System Proteins; C013683:sodium nucleinate
vernacular_title: Lechenie sekretornykh srednikh otitov.