title: Handling of blood specimens for glucose analysis.
abstract: There is no consensus concentration of sodium fluoride (NaF) required for preserving glucose in blood specimens. We examined the effectiveness of different concentrations of NaF. Glucose concentration in blood samples decreased with time, despite the presence of a high concentration of NaF (12 g/l). The decrease in glucose concentration was less with increasing amounts of NaF but could not be totally abolished. The clinical implications of these pre-analytical errors is discussed.
authors.affiliation: Department of Chemical Pathology, Chinese University of Hong Kong, Prince of Wales Hospital.
authors.forename: A Y
authors.initials: AY
authors.lastname: Chan
authors.forename: C S
authors.initials: CS
authors.lastname: Ho
authors.forename: C S
authors.initials: CS
authors.lastname: Cockram
authors.forename: R
authors.initials: R
authors.lastname: Swaminathan
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis*; D001793:Blood Preservation / Q000379:methods; D004305:Dose-Response Relationship, Drug; D006801:Humans; D012969:Sodium Fluoride / Q000494:pharmacology; D013048:Specimen Handling / Q000379:methods*
chemical_list: D001786:Blood Glucose; D012969:Sodium Fluoride