title: Evaluation of the Beckman Synchron CX4 clinical chemistry analyzer in a hospital laboratory.
abstract: The Beckman Synchron CX4 random-access multianalyzer was evaluated in a medium sized hospital laboratory. The instrument does end-point, rate, and multipoint assays and carries on-board reagents for 24 tests. In addition to predefined tests, the instrument can be programmed for 100 user-defined tests; these are stored on the hard disk and can utilize up to three component reagents each. The throughput is 200 tests per hour. There is stat testing capability. In our evaluation, within-run and between-run precision and linearity were good, and no reagent carryover was detected. There was good correlation with the in-house methodology for the 19 tests evaluated. A disadvantage at the time of evaluation was interference by elevated bilirubin on creatinine, phosphorus, uric acid, and triglycerides. This problem of interference is being addressed by the manufacturer.
authors.affiliation: Department of Clinical Biochemistry, University of Toronto, Ontario, Canada.
authors.forename: T
authors.initials: T
authors.lastname: Ambus
authors.forename: N
authors.initials: N
authors.lastname: Korogyi
authors.forename: F
authors.initials: F
authors.lastname: DeCampos
authors.forename: B
authors.initials: B
authors.lastname: Groom
authors.forename: V T
authors.initials: VT
authors.lastname: Innanen
mesh_terms: D001322:Autoanalysis / Q000295:instrumentation* / Q000592:standards; D001663:Bilirubin / Q000097:blood; D001774:Blood Chemical Analysis / Q000295:instrumentation* / Q000592:standards; D002624:Chemistry, Clinical / Q000295:instrumentation* / Q000592:standards; D005069:Evaluation Studies as Topic; D006461:Hemolysis; D006949:Hyperlipidemias / Q000097:blood; D007755:Laboratories, Hospital; D011786:Quality Control
chemical_list: D001663:Bilirubin