title: [Role of drug assays in the treatment of epileptic patients].
abstract: Drug assays play an important role in the control of antiepileptic treatment because the relationship between the serum concentration of an active drug and its therapeutic effects and side-effects is closer than between dose and effect. Bioavailability, protein binding and drug elimination are subject to inter- and intraindividual variations. However, it is important to remember that the optimal therapeutic ranges reported for serum levels are only a guideline to drug therapy. It is the patient who must be treated and not the serum level.
authors.affiliation: National Center for Epilepsy, Sandvika, Norvège.
authors.forename: S I
authors.initials: SI
authors.lastname: Johannessen
mesh_terms: D000367:Age Factors; D000927:Anticonvulsants / Q000009:adverse effects / Q000097:blood* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D004827:Epilepsy / Q000188:drug therapy*; D006801:Humans
chemical_list: D000927:Anticonvulsants
vernacular_title: Rôle du dosage des médicaments dans le traitement des épileptiques.