title: Acute renal failure due to pyelonephritis.
abstract: Acute renal failure developed in a 3-year-old boy with acute pyelonephritis. Renal biopsy showed acute interstitial infiltration of neutrophils and macrophages. There were also glomerulitis and capillary tuft thrombosis. He required peritoneal dialysis, but subsequently recovered renal function. Prompt antimicrobial therapy is crucial to insure a favorable outcome. Pyelonephritis is an unusual cause of acute renal failure in infants and children.
authors.affiliation: Department of Pediatrics, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, N.C.
authors.forename: W B
authors.initials: WB
authors.lastname: Lorentz
authors.forename: S
authors.initials: S
authors.lastname: Iskandar
authors.forename: M C
authors.initials: MC
authors.lastname: Browning
authors.forename: G D
authors.initials: GD
authors.lastname: Reynolds
mesh_terms: D000208:Acute Disease; D058186:Acute Kidney Injury / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D000900:Anti-Bacterial Agents; D002675:Child, Preschool; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D006801:Humans; D008297:Male; D010530:Peritoneal Dialysis; D011704:Pyelonephritis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents