title: Clostridium difficile-associated diarrhea after norfloxacin.
abstract: Although theoretically the spectrum of antimicrobial quinolone antibiotics are at low risk of producing Clostridium difficile overgrowth and diarrhea, a patient developed this clinical problem while receiving norfloxacin. We review the antimicrobial activity of the quinolone antibiotics, with respect to their predisposition for producing C. difficile-induced diarrhea.
authors.affiliation: Department of Medicine, Northwestern University Medical School, Chicago, Illinois.
authors.forename: E D
authors.initials: ED
authors.lastname: Ehrenpreis
authors.forename: M W
authors.initials: MW
authors.lastname: Lievens
authors.forename: R M
authors.initials: RM
authors.lastname: Craig
mesh_terms: D000368:Aged; D003015:Clostridium Infections / Q000139:chemically induced* / Q000150:complications; D003967:Diarrhea / Q000139:chemically induced* / Q000150:complications; D005759:Gastroenteritis / Q000188:drug therapy; D006801:Humans; D008297:Male; D009643:Norfloxacin / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D009643:Norfloxacin