title: Application of encapsulated enzyme dispersed in a continuous stirred tank reactor.
abstract: An application of encapsulated lipase to the hydrolysis of triacetin (triglyceride of acetic acid) was carried out with a continuous stirred tank reactor, in which the encapsulated enzyme was dispersed. An automatic control device to control pH of the reaction mixture at a desired level was designed and installed in the reactor system. Conversion of triacetin at the steady state operation with pH controlled became significantly higher than that without pH control. A particular kinetic model proposed by the authors, which regarded the mass-transfer through the wall of microcapsules as a dominant resistance to the overall reaction rate, was also applicable to simulate the behaviour of CSTR system as in the case of packed-bed reactor.
authors.affiliation: Department of Chemical Engineering, Tokyo University of Agriculture and Technology, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Iso
authors.forename: H
authors.initials: H
authors.lastname: Masumoto
authors.forename: S
authors.initials: S
authors.lastname: Urushiyama
authors.forename: S
authors.initials: S
authors.lastname: Omi
mesh_terms: D004339:Drug Compounding / Q000379:methods; D004800:Enzymes, Immobilized; D006868:Hydrolysis; D008049:Lipase; D014215:Triacetin; D014280:Triglycerides
chemical_list: D004800:Enzymes, Immobilized; D014280:Triglycerides; D008049:Lipase; D014215:Triacetin