title: [Treatment of cancer of the anal canal with combination radiochemotherapy: apropos of 12 cases].
abstract: We present 12 patients (3 male, 9 female) aged from 53-88 years with squamous cell cancer of the anal canal treated with combined radiotherapy-chemotherapy (5 FU-mitomycin C); the distribution of the tumours was 2 T4, 6 T3, 3 T2, 1 T1). In 11 patients evaluated, complete remission was obtained in 8 with partial remission in 2 others. In spite of this good result with combined treatment, 4 patients had a recurrence between 9 and 26 months. Five patients survived and 2 died without disease (16-38 month), 3 patients died and one survived with disease. The small series confirms the efficacy of this combination which treated bulky tumours (T3-T4). It is necessary however to compare these results with radiation alone in a randomised trial.
authors.affiliation: Centre Antoine-Lacassagne, Nice, France.
authors.forename: J
authors.initials: J
authors.lastname: Bourry
authors.forename: J L
authors.initials: JL
authors.lastname: Lagrange
authors.forename: P
authors.initials: P
authors.lastname: Chauvel
authors.forename: E
authors.initials: E
authors.lastname: François
authors.forename: M
authors.initials: M
authors.lastname: Abbes
authors.forename: J
authors.initials: J
authors.lastname: Monticelli
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001005:Anus Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors
vernacular_title: Traitement des cancers du canal anal par association radio-chimiothérapie: à propos de 12 cas.