Sudden cortical blindness following transient enhancement of steroids administered in congenital adrenal hyperplasia (case report).
A case of cortical blindness developed in an infant who suffered from congenital adrenal hyperplasia and was hospitalized for enteritis is reported. The severe but transient hypertension recorded raises the possibility that the increased doses of steroid administered may have contributed to the pathogenesis of visual impairment.
Decsi
T
T
Department of Paediatrics, University Medical School, Pécs, Hungary.
Kosztolányi
G
G
Czopf
J
J
D000208:Acute Disease; D000312:Adrenal Hyperplasia, Congenital / Q000188:drug therapy* / Q000503:physiopathology; D001766:Blindness / Q000139:chemically induced* / Q000503:physiopathology; D002540:Cerebral Cortex / Q000473:pathology*; D004357:Drug Synergism; D005074:Evoked Potentials, Visual; D005438:Fludrocortisone / Q000009:adverse effects*; D006801:Humans; D006973:Hypertension / Q000139:chemically induced; D007223:Infant; D008297:Male; D011239:Prednisolone / Q000009:adverse effects / Q000031:analogs & derivatives*
D011239:Prednisolone; C021322:prednisolone hemisuccinate; D005438:Fludrocortisone