title: Characterization and localization to human chromosome 1 of human fast-twitch skeletal muscle calsequestrin gene.
abstract: A genomic clone encoding human fast-twitch skeletal muscle calsequestrin was isolated, and the amino acid sequence of the protein and the exon-intron boundaries of the gene were deduced from its sequence. A comparison with the rabbit gene showed that the sequence Glu-Asp-Asp-Asp-Asp near the COOH terminus of the rabbit sequence is lacking in the human gene. The calsequestrin gene was assigned to human chromosome 1 through the use of a human-mouse somatic cell hybrid mapping panel.
authors.affiliation: Banting and Best Department of Medical Research, University of Toronto, Ontario, Canada.
authors.forename: J
authors.initials: J
authors.lastname: Fujii
authors.forename: H F
authors.initials: HF
authors.lastname: Willard
authors.forename: D H
authors.initials: DH
authors.lastname: MacLennan
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002155:Calsequestrin / Q000032:analysis / Q000235:genetics*; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1 / Q000648:ultrastructure*; D004247:DNA / Q000032:analysis / Q000235:genetics; D005796:Genes / Q000235:genetics*; D006801:Humans; D006822:Hybrid Cells / Q000032:analysis / Q000166:cytology / Q000648:ultrastructure; D008969:Molecular Sequence Data; D009124:Muscle Proteins / Q000235:genetics*; D009132:Muscles / Q000032:analysis* / Q000502:physiology; D012377:Rodentia
chemical_list: D002155:Calsequestrin; D009124:Muscle Proteins; D004247:DNA