title: Toxicity of the pyrethroid insecticide fenvalerate to a fresh water fish, Tilapia mossambica (Peters): changes in glycogen metabolism of muscle.
abstract: Toxic effects of a pyrethroid insecticide, fenvalerate, on fish muscle glycogen metabolism were investigated. Estimations were made after 10 and 20 days of exposure, and altered muscle glycogen metabolism was observed. The changes included a significant (P less than 0.001) decrease in the levels of glycogen, pyruvate, maleate dehydrogenase (MDH), succinate dehydrogenase (SDH), and phosphorylase a, b, and ab activities, while elevated levels of lactic acid, aldolase, and lactate dehydrogenase (LDH) activity were observed under fenvalerate intoxication. There was a decrease in opercular movement and oxygen consumption with an increase in concentration of fenvalerate.
authors.affiliation: Department of Zoology, Sri Venkateswara University, Tirupati, India.
authors.forename: V
authors.initials: V
authors.lastname: Radhaiah
authors.forename: K J
authors.initials: KJ
authors.lastname: Rao
mesh_terms: D000818:Animals; D005399:Fishes / Q000378:metabolism*; D005634:Fructose-Bisphosphate Aldolase / Q000378:metabolism; D006003:Glycogen / Q000378:metabolism*; D007306:Insecticides / Q000633:toxicity*; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D007773:Lactates / Q000378:metabolism; D019344:Lactic Acid; D008291:Malate Dehydrogenase / Q000378:metabolism; D009132:Muscles / Q000187:drug effects* / Q000378:metabolism; D009570:Nitriles; D010101:Oxygen Consumption / Q000187:drug effects; D006005:Phosphorylases / Q000378:metabolism; D011722:Pyrethrins / Q000633:toxicity*; D011773:Pyruvates / Q000378:metabolism; D019289:Pyruvic Acid; D013385:Succinate Dehydrogenase / Q000378:metabolism
chemical_list: D007306:Insecticides; D007773:Lactates; D009570:Nitriles; D011722:Pyrethrins; D011773:Pyruvates; D019344:Lactic Acid; D019289:Pyruvic Acid; D006003:Glycogen; D007770:L-Lactate Dehydrogenase; D008291:Malate Dehydrogenase; D013385:Succinate Dehydrogenase; D006005:Phosphorylases; D005634:Fructose-Bisphosphate Aldolase; C017690:fenvalerate