Gallstones and obesity: observations from 352 autopsied patients.
Obesity has been considered a risk factor for gallstones, but the association remains controversial. To test this possible association we studied autopsy reports of 352 adult patients. These included 248 obese and 104 non-obese patients. The body mass index, defined as body weight in kg/m2, was used to assess and measure the degree of obesity and to divide patients into two groups: Group 1 (normal weight and mildly obese individuals) and Group 2 (moderately and severely obese individuals). The comparative frequency of gallstones in these two groups was statistically analyzed by the Mantel-Haenzel method with stratification for age, sex, and diabetes mellitus. No significant association between gallstones and obesity (p less than 0.2) was found.
Fraire
A E
AE
Department of Pathology, Baylor College of Medicine, Houston, TX 77030.
Johnson
E H
EH
Kim
H S
HS
Titus
J L
JL
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002769:Cholelithiasis / Q000473:pathology*; D003920:Diabetes Mellitus / Q000473:pathology; D005260:Female; D005704:Gallbladder / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000473:pathology*; D009767:Obesity, Morbid / Q000473:pathology; D012307:Risk Factors