title: [Plasmocellular leukemia with IgD paraproteinemia].
abstract: The authors describe the case of an 80-year-old woman with a plasmocytoma IgD-lambda, which developed into plasmocellular leukaemia. The laboratory finding reminded at first of chronic lymphatic leukaemia. The correct diagnosis was assisted by marked leucocytosis with the release of a major number of plasmatic cells into the peripheral blood stream. The finding was confirmed on the basis of sternal puncture, cytochemical examination, immunochemical examination of the blood and urine and X-ray of the skull. Treatment led to marked clinical and laboratory improvement. The patient died, however, from pneumonia three months after establishment of the diagnosis. Post-mortem examination revealed an extensive infiltration of many organs and a myelomatous kidney. The authors present some differential diagnostic reflections on plasmocellular leukaemia.
authors.affiliation: Oddĕlení klinické hematologie fakultní nemocnice Brno.
authors.forename: F
authors.initials: F
authors.lastname: Matĕja
authors.forename: M
authors.initials: M
authors.lastname: Tichý
authors.forename: J
authors.initials: J
authors.lastname: Novotný
authors.forename: T
authors.initials: T
authors.lastname: Foukal
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D007072:Immunoglobulin D; D007952:Leukemia, Plasma Cell / Q000150:complications* / Q000175:diagnosis; D010265:Paraproteinemias / Q000150:complications* / Q000175:diagnosis
chemical_list: D007072:Immunoglobulin D
vernacular_title: Plasmocelulární leukémie s paraproteinémií IgD.