The photoprotective potential of the new superpotent sunscreens.
A sun protection factor (SPF)-15 and an SPF-30 sunscreen were compared with regard to their ability to prevent sunburn cell formation after the exposure of human skin to a standardized dose of solar-simulated radiation. The SPF-30 sunscreen provided a significantly superior degree of photoprotection and almost prevented sunburn cell induction. Because sunburn cells may be markers of ultraviolet radiation-induced damage to DNA, the new superpotent sunscreens should offer an advantage in the prevention of skin cancer and long-term actinic damage to skin.
Kaidbey
K H
KH
Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia 19104.
D000293:Adolescent; D000328:Adult; D004341:Drug Evaluation; D004890:Erythema / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D008875:Middle Aged; D013471:Sunburn / Q000517:prevention & control*; D013473:Sunscreening Agents / Q000008:administration & dosage*; D014466:Ultraviolet Rays
D013473:Sunscreening Agents