title: Malignant carcinoid syndrome. Failure of anti-oestrogenic therapy.
abstract: A pre-menopausal patient with a six-year history of symptoms of the metastatic carcinoid syndrome leading to progressively worsening carcinoid heart disease is described. The failure of anti-oestrogenic therapy (sequential bilateral oophorectomy and Tamoxifen therapy) to halt progression of disease was documented. Death resulted from right ventricular failure associated with pulmonary and tricuspid valvular disease.
authors.affiliation: San Fernando General Hospital, Trinidad.
authors.forename: K
authors.initials: K
authors.lastname: Ramcharan
authors.forename: C
authors.initials: C
authors.lastname: Pooransingh
authors.forename: C
authors.initials: C
authors.lastname: Harnarayan
authors.forename: M
authors.initials: M
authors.lastname: Shah-Parsad
authors.forename: H
authors.initials: H
authors.lastname: McFarlane
mesh_terms: D001706:Biopsy; D005260:Female; D006801:Humans; D008303:Malignant Carcinoid Syndrome / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D008875:Middle Aged; D013629:Tamoxifen / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D013629:Tamoxifen