title: Familial multiple upper gastrointestinal leiomyoma.
abstract: This report describes three adult members of a family who developed leiomyomas in the muscularis propria of their upper gastrointestinal tract. When in their thirties, numerous leiomyomas were present in ileum and jejunum. In their sixties, multiple and confluent esophageal leiomyomas formed the clinical picture of esophageal leiomyomatosis. Presenting symptoms were esophageal obstruction and hemorrhage. This is the first case in the published literature describing an association of familial multiple upper gastrointestinal leiomyomas with esophageal leiomyomatosis.
authors.affiliation: Kennedy Memorial Hospital, Stratford, New Jersey.
authors.forename: R M
authors.initials: RM
authors.lastname: Rosen
mesh_terms: D000328:Adult; D000368:Aged; D004067:Digestive System Neoplasms / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007889:Leiomyoma / Q000235:genetics* / Q000473:pathology; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000235:genetics* / Q000473:pathology; D010375:Pedigree