Cryptosporidiosis and acute leukaemia.
Six children with cryptosporidiosis, concurrently receiving chemotherapy for acute leukaemia (n = 5) and lymphoma (n = 1), are described. Two died with evidence of persistent infection. Modification of the chemotherapy regimens in the other four children was associated with successful eradication of the pathogen and permitted continued treatment of the primary disease.
Foot
A B
AB
Regional Paediatric Oncology Unit, Royal Hospital for Sick Children, Bristol.
Oakhill
A
A
Mott
M G
MG
D002648:Child; D002675:Child, Preschool; D003457:Cryptosporidiosis / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D007223:Infant; D008297:Male; D008727:Methotrexate / Q000009:adverse effects; D009503:Neutropenia / Q000150:complications; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D015572:Spiramycin / Q000627:therapeutic use
D015572:Spiramycin; D008727:Methotrexate