title: Purification and amino-terminal sequence analysis of the complement-fixing and precipitin antigens from Coccidioides immitis.
abstract: Two proteins (21 and 48 kilodaltons) purified from endospore-spherule culture filtrates of Coccidioides immitis are identified as precipitin and complement-fixing antigens, respectively. To allow specific structural comparison to antigens identified by other investigators and as a first step to eventual serodiagnostic antigen production by recombinant DNA technology, amino-terminal amino acid sequences were determined for these antigens.
authors.affiliation: Department of Dermatology, University of California, San Francisco 94143.
authors.forename: S
authors.initials: S
authors.lastname: Resnick
authors.forename: B
authors.initials: B
authors.lastname: Zimmer
authors.forename: D
authors.initials: D
authors.lastname: Pappagianis
authors.forename: A
authors.initials: A
authors.lastname: Eakin
authors.forename: J
authors.initials: J
authors.lastname: McKerrow
mesh_terms: D000595:Amino Acid Sequence; D000946:Antigens, Fungal / Q000302:isolation & purification*; D003045:Coccidioides / Q000276:immunology*; D003047:Coccidioidomycosis / Q000175:diagnosis / Q000276:immunology; D003168:Complement Fixation Tests; D005656:Fungal Proteins / Q000276:immunology / Q000302:isolation & purification; D006801:Humans; D008969:Molecular Sequence Data; D008970:Molecular Weight; D011234:Precipitins / Q000302:isolation & purification; D012698:Serologic Tests
chemical_list: D000946:Antigens, Fungal; D005656:Fungal Proteins; D011234:Precipitins