[The direct use of cytogenetic data for plotting prognostic curves of the dynamics of neutrophil count after acute relatively uniform gamma irradiation (based on data from the victims of the accident at the Chernobyl Atomic Electric Power Station].
A considerable number of irradiated persons appeared as a result of the accident at the Chernobyl Atomic Power Station. Analysis of chromosome aberrations and detailed hematological investigations were performed in them. Relatively uniform affection of the hemopoietic tissue could be anticipated on the basis of the results of the cytogenetic analysis in most of these persons who had been exposed to radiation at doses that were critical for the development of the bone marrow syndrome. It made it possible to establish direct quantitative relationship between the indices of a postradiation curve of the time course of the neutrophil count in peripheral blood and the mean rate of dicentrics in lymphocytes for cases of relatively uniform irradiation and to plot prognostic curves of neutrophils for different frequencies of dicentrics.
Piatkin
E K
EK
Chirkov
A A
AA
Solov'ev
V Iu
VIu
Nugis
V Iu
VIu
D000059:Accidents; D002869:Chromosome Aberrations / Q000235:genetics*; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D006801:Humans; D007958:Leukocyte Count / Q000528:radiation effects; D009503:Neutropenia / Q000097:blood / Q000209:etiology; D009504:Neutrophils / Q000528:radiation effects* / Q000648:ultrastructure; D009688:Nuclear Reactors; D011210:Power Plants; D011379:Prognosis; D011832:Radiation Injuries / Q000097:blood / Q000209:etiology; D013997:Time Factors; D014455:Ukraine
Priamoe ispol'zovanie tsitogeneticheskikh dannykh dlia postroeniia prognosticheskikh krivykh dinamiki chisla neĭtrofilov posle ostrogo otnositel'no ravnomerno gamma-oblucheniia (na materiale postradavshikh pri avarii na Chernobylskoĭ AES).