title: A new predictive equation for resting energy expenditure in healthy individuals.
abstract: A predictive equation for resting energy expenditure (REE) was derived from data from 498 healthy subjects, including females (n = 247) and males (n = 251), aged 19-78 y (45 +/- 14 y, mean +/- SD). Normal-weight (n = 264) and obese (n = 234) individuals were studied and REE was measured by indirect calorimetry. Multiple-regression analyses were employed to drive relationships between REE and weight, height, and age for both men and women (R2 = 0.71): REE = 9.99 x weight + 6.25 x height - 4.92 x age + 166 x sex (males, 1; females, 0) - 161. Simplification of this formula and separation by sex did not affect its predictive value: REE (males) = 10 x weight (kg) + 6.25 x height (cm) - 5 x age (y) + 5; REE (females) = 10 x weight (kg) + 6.25 x height (cm) - 5 x age (y) - 161. The inclusion of relative body weight and body-weight distribution did not significantly improve the predictive value of these equations. The Harris-Benedict Equations derived in 1919 overestimated measured REE by 5% (p less than 0.01). Fat-free mass (FFM) was the best single predictor of REE (R2 = 0.64): REE = 19.7 x FFM + 413. Weight also was closely correlated with REE (R2 = 0.56): REE = 15.1 x weight + 371.
authors.affiliation: Nutrition Education and Research Program, University of Nevada School of Medicine, Reno 89557.
authors.forename: M D
authors.initials: MD
authors.lastname: Mifflin
authors.forename: S T
authors.initials: ST
authors.lastname: St Jeor
authors.forename: L A
authors.initials: LA
authors.lastname: Hill
authors.forename: B J
authors.initials: BJ
authors.lastname: Scott
authors.forename: S A
authors.initials: SA
authors.lastname: Daugherty
authors.forename: Y O
authors.initials: YO
authors.lastname: Koh
mesh_terms: D000328:Adult; D000368:Aged; D001827:Body Height; D001835:Body Weight; D002153:Calorimetry, Indirect; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D012885:Skinfold Thickness