title: An investigation of the clinical use of botulinum toxin A as a postoperative adjustment procedure in the therapy of strabismus.
abstract: Attempts to circumvent multiple surgical procedures are an integral part of the history of investigations in strabismus. In 1973, Botulinum toxin A (Oculinum) injections into human EOM was proposed as an alternate method to surgery for strabismus and has since proved to be effective. This article reports the results from a retrospective investigation of EOM Oculinum injection used in the postoperative period as an alternate to additional surgery. It is difficult to establish whether Oculinum altered the time span of the clinical course in these patients, but when it was effective, it provided unprecedented convenience.
authors.affiliation: Department of Ophthalmology, Medical College of Virginia, Richmond 23298.
authors.forename: K W
authors.initials: KW
authors.lastname: McNeer
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001905:Botulinum Toxins / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005133:Eye Movements / Q000187:drug effects; D006801:Humans; D007273:Injections, Intramuscular; D008875:Middle Aged; D009801:Oculomotor Muscles / Q000187:drug effects; D011184:Postoperative Period; D011379:Prognosis; D012189:Retrospective Studies; D013285:Strabismus / Q000188:drug therapy* / Q000601:surgery
chemical_list: D001905:Botulinum Toxins