[Subfractions of high density lipoproteins in relation to age].
In dependence on age women show both elevated levels of serum triglycerides and changes of lipid composition of HDL. A decrease of HDL- and HDL2-cholesterol levels and an increase of HDL- and HDL2-triglyceride concentrations are seen in the group of older persons. The concentration of HDL3-phospholipids decreases in dependence on aging. The content of triglycerides and the relation triglyceride/cholesterol of the subfraction HDL2, but not of HDL3, show positive correlations with the level of serum triglycerides. These changes are related to an age-dependent decrease of post-heparin lipolytic activity and a remodulation of HDL in dependence on the relation of the concentration of triglyceride rich lipoproteins and HDL.
Richter
V
V
Institut für Klinische Chemie und Laboratoriumsdiagnostik, Bereich Medizin der Karl-Marx-Universität Leipzig.
Rassoul
F
F
Purcz
T
T
Faki
R
R
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000097:blood*; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D005260:Female; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood* / Q000145:classification; D053439:Lipoproteins, HDL2; D053440:Lipoproteins, HDL3; D008875:Middle Aged; D010743:Phospholipids / Q000097:blood; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; C034396:HDL-triglyceride; D008075:Lipoproteins, HDL; D053439:Lipoproteins, HDL2; D053440:Lipoproteins, HDL3; D010743:Phospholipids; D014280:Triglycerides; D002784:Cholesterol
Subfraktionen der High-density-Lipoproteine (HDL) in Abhängigkeit vom Lebensalter.