title: In vivo 19F spin relaxation in index finger bones.
abstract: 19F free induction decay (FID) signals have been observed from the index fingers of four male and two female adult volunteers using a 27-MHz pulsed nuclear magnetic resonance spectrometer equipped with a split ring resonator probe. The value of the in vivo spin-lattice relaxation time T1 of the fluoride ions naturally accumulated in bone mineral has been determined to be 2.0 +/- 0.3 s. The shape of the observed FID signals in the inhomogeneous external magnetic field indicates that the F distribution is not uniform along the length of the finger. The fluoride ion content of the index finger (within a 65-mm length from its distal end) was measured with a sensitivity of +/- 0.5 mg F within a 30-min observation time.
authors.affiliation: Department of Physics, University of Toronto, Canada.
authors.forename: R F
authors.initials: RF
authors.lastname: Code
authors.forename: J E
authors.initials: JE
authors.lastname: Harrison
authors.forename: K G
authors.initials: KG
authors.lastname: McNeill
authors.forename: M
authors.initials: M
authors.lastname: Szyjkowski
mesh_terms: D000328:Adult; D001842:Bone and Bones / Q000032:analysis*; D005260:Female; D005385:Fingers; D005459:Fluorides / Q000032:analysis*; D005461:Fluorine; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation; D008297:Male; D008961:Models, Structural; D013997:Time Factors
chemical_list: D005461:Fluorine; D005459:Fluorides