Seminal plasma anti-sperm antibodies and IVF: the effect of semen sample collection into 50% serum.
A retrospective analysis was carried out which studied IVF results for couples in whom the male partner had anti-sperm antibodies in seminal plasma, as judged by a positive MAR test. Of the 59 couples studied over a total of 113 cycles, 30 had IVF semen samples collected into sterile, dry pots. Thirty-eight of the couples had samples collected into medium containing 50% serum, and nine couples underwent separate treatment cycles with samples collected both dry and into 50% serum. The results demonstrate that the addition of serum to sample collection pots significantly improves the oocyte fertilization rate and is followed by a greater chance of conception for these couples.
Elder
K T
KT
Bourn Hallam Infertility Centre, Bourn Hall Clinic, Cambridge, UK.
Wick
K L
KL
Edwards
R G
RG
D000906:Antibodies / Q000502:physiology*; D001769:Blood; D005260:Female; D005306:Fertilization; D005307:Fertilization in Vitro; D006801:Humans; D008297:Male; D011247:Pregnancy; D012661:Semen / Q000276:immunology*; D013048:Specimen Handling / Q000379:methods*; D013076:Sperm Count; D013081:Sperm Motility; D013094:Spermatozoa / Q000276:immunology*
D000906:Antibodies