Dose-response to pancuronium in identical twins.
The dose-response to pancuronium was determined in identical twins within an hour with the same anesthetic technique. The dose-response curves did not differ from parallelism, but one infant was more sensitive to pancuronium than the other. The recovery rates were also different. The variation in the dose response to pancuronium seems to extend to identical twins.
Goudsouzian
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Department of Anaesthesia, Harvard Medical School, Massachusetts General Hospital, Boston.
D000771:Anesthesia, Intravenous; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007223:Infant; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D009132:Muscles / Q000187:drug effects; D010197:Pancuronium / Q000008:administration & dosage / Q000494:pharmacology*; D014427:Twins; D014430:Twins, Monozygotic
D010197:Pancuronium