title: Urography with spasmolytics.
abstract: The effects of glucagon (1 mg i.v.) and hyoscine butylbromide (Buscopan 20 mg i.v.) and placebo on the visualization of the pyelocalyceal systems and ureters was compared in a routine urography with abdominal compression in a double-blind, randomized trial comprising 189 kidneys and ureters. The visualization of the ureters in the supine position was highly significantly better than in the prone. In the prone position the ureteral visualization with Buscopan was marginally significantly better than with placebo or glucagon. Otherwise, neither Buscopan nor glucagon improved the pyeloureteral visualization. However, with glucagon the pyelocalyceal visualization was highly significantly poorer than with placebo, and marginally significantly poorer than with Buscopan.
authors.affiliation: Department of Diagnostic Radiology, Surgical Hospital, Helsinki, Finland.
authors.forename: J
authors.initials: J
authors.lastname: Kinnunen
authors.forename: O
authors.initials: O
authors.lastname: Saarinen
authors.forename: J
authors.initials: J
authors.lastname: Ahovuo
authors.forename: J
authors.initials: J
authors.lastname: Edgren
authors.forename: L
authors.initials: L
authors.lastname: Laasonen
authors.forename: J
authors.initials: J
authors.lastname: Pietilä
mesh_terms: D000818:Animals; D002086:Butylscopolammonium Bromide; D005260:Female; D005934:Glucagon; D006417:Hematuria / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010276:Parasympatholytics; D011507:Proteinuria / Q000000981:diagnostic imaging*; D012602:Scopolamine Derivatives; D014552:Urinary Tract Infections / Q000000981:diagnostic imaging*; D014563:Urodynamics / Q000187:drug effects; D014567:Urography / Q000379:methods*
chemical_list: D010276:Parasympatholytics; D012602:Scopolamine Derivatives; D002086:Butylscopolammonium Bromide; D005934:Glucagon