[Use of fibrin glue in prevention and therapy of intra-abdominal adhesions].
In prevention of the recurrent intestinal obstruction we performed at the Department of Pediatric Surgery of the University of Mannheim a sutureless plication of the small bowel with fibrin glue only over the last 7-year period. The postoperative course was uncomplicated in all patients. The clinical and experimental experiences suggest that the high concentrated human fibrinogen is able to start healing of the lesions of the serosa to prevent intraabdominal adhesions prospectively. Furthermore the time saving and easy procedure is to be stressed. First of all the high risk of tissue necrosis or intestinal perforation due to ischemia by sutures and stitches like in the traditional technique of plication is not present.
Brands
W
W
Kinderchirurgische Klinik, Universität Heidelberg.
Diehm
T
T
Lochbühler
H
H
König
M
M
Stock
M
M
D000818:Animals; D002675:Child, Preschool; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage*; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007415:Intestinal Obstruction / Q000601:surgery*; D008643:Mesentery / Q000601:surgery*; D011183:Postoperative Complications / Q000517:prevention & control* / Q000601:surgery; D051381:Rats; D012008:Recurrence; D012086:Reoperation; D000267:Tissue Adhesions; D014945:Wound Healing / Q000187:drug effects
D015718:Fibrin Tissue Adhesive
Die Anwendung des Fibrinklebers zur Prophylaxe und Therapie intraabdomineller Adhäsionen.