title: Features of systemic sclerosis (scleroderma) in South African goldminers.
abstract: Systemic sclerosis is more common among men exposed to silica-containing dust than in the general male population. The clinical features of systemic sclerosis in a group of 24 black goldminers are described. The better-known presenting features of systemic sclerosis, including Raynaud's phenomenon and dysphagia, were rare in this population. Initial presentation was usually with nonspecific features including swelling of the feet or hands, weakness, arthralgia or symptoms of respiratory or cardiac disease. Clinical evidence of pleural or pericardial involvement was more common than is usually described in non-occupational systemic sclerosis. Interstitial lung disease was frequently encountered and renal disease was rare.
authors.affiliation: Department of Medicine, Ernest Oppenheimer Hospital, Welkom, OFS.
authors.forename: R L
authors.initials: RL
authors.lastname: Cowie
authors.forename: R D
authors.initials: RD
authors.lastname: Dansey
mesh_terms: D000328:Adult; D006046:Gold; D006801:Humans; D008297:Male; D008875:Middle Aged; D008906:Mining; D009784:Occupational Diseases / Q000503:physiopathology*; D012595:Scleroderma, Systemic / Q000503:physiopathology*; D013019:South Africa
chemical_list: D006046:Gold