The absolute configuration of decilonitrose, a sugar component of decilorubicin, is undoubtedly 2,3,6-trideoxy-3-C-methyl-3-nitro-L-ribo-hexopyranose.
The absolute structure of decilonitrose, a sugar component of an antitumor antibiotic decilorubicin was decided to be 2,3,6-trideoxy-3-C-methyl-3-nitro-L-ribo-hexopyranose by synthesis of its methyl beta-glycoside starting from L-rhamnose through the 3-ulose. In the synthetic route, any configurational ambiguities do not exist.
Nishimura
Y
Y
Institute of Microbial Chemistry, Tokyo, Japan.
Ishii
K
K
Kondo
S
S
D018943:Anthracyclines; D000903:Antibiotics, Antineoplastic / Q000032:analysis*; D055598:Chemical Phenomena; D002621:Chemistry; D006601:Hexoses / Q000032:analysis*; D008968:Molecular Conformation; D015394:Molecular Structure
D018943:Anthracyclines; D000903:Antibiotics, Antineoplastic; D006601:Hexoses; C038318:decilorubicin; C038320:decilonitrose