title: The effects of menthol on reaction time and nasal sensation of airflow in subjects suffering from the common cold.
abstract: The effects of sucking a lozenge containing 11 mg L-menthol on reaction time and nasal sensation were investigated in a double blind trial on 60 subjects suffering from the common cold. Reaction time was determined by measuring the response time to a stimulus presented on a microcomputer screen and nasal sensation was scored on a visual analogue scale. Menthol ingestion compared to placebo caused a significant increase in nasal sensation of airflow which persisted for up to 30 min. The simple and choice reaction times measured before ingestion of the lozenge were similar to those found in healthy uninfected subjects and there was no change in reaction time after ingestion of menthol.
authors.affiliation: Department of Physiology, University of Wales, Cardiff, UK.
authors.forename: R
authors.initials: R
authors.lastname: Eccles
authors.forename: S
authors.initials: S
authors.lastname: Morris
authors.forename: M S
authors.initials: MS
authors.lastname: Jawad
mesh_terms: D000293:Adolescent; D000328:Adult; D003139:Common Cold / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008610:Menthol / Q000494:pharmacology / Q000627:therapeutic use*; D012123:Pulmonary Ventilation / Q000187:drug effects*; D011930:Reaction Time / Q000187:drug effects*
chemical_list: D008610:Menthol