C-reactive protein during normal pregnancy.
Serum C-reactive protein (CRP) is determined in a prospective longitudinal study of 60 low-risk pregnant women. CRP is also measured in umbilical-cord blood after delivery. The serum CRP concentrations seem to be independent of pregnancy and gestational age. The 95th percentile is estimated to be 20 mg/l, and this value is considered as the upper limit of normal. A rise in CRP level is considered more predictive of infection than a determination of a single high value. CRP does not cross the placental barrier, and may therefore be useful in diagnosing infections in newborns.
Nielsen
F R
FR
Department of Obstetrics and Gynecology, Sct Maria Hospital, Vejle, Denmark.
Bek
K M
KM
Rasmussen
P E
PE
Qvist
I
I
Tobiassen
M
M
D002097:C-Reactive Protein / Q000378:metabolism*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis; D007239:Infections / Q000175:diagnosis; D008137:Longitudinal Studies; D011237:Predictive Value of Tests; D011247:Pregnancy / Q000097:blood*; D011446:Prospective Studies; D012016:Reference Values
D002097:C-Reactive Protein