title: Induction of labour postdates in primiparae using vaginal prostaglandin tablets.
abstract: The management of pregnancy after 40 completed weeks remains controversial because induction of labour has been, in the past, associated with an increase in the incidence of caesarean section. This study examined the use of vaginal prostaglandin tablets for the induction of labour in selected primiparae after forty one weeks of pregnancy. The outcome of prostaglandin induction in 118 consecutive patients was compared with the outcome in 90 consecutive patients who went into labour spontaneously at the same gestation before induction could be undertaken. The active management of labour was applied in both groups and, therefore, the management of labour was strictly standardised. There was no difference between the two groups in the mode of delivery. Nor was prostaglandin induction associated with an increased incidence of prolonged labour. In selected primiparae, the cautious use of vaginal prostaglandin tablets can induce labour successfully postdates without increasing the complications of labour. A larger study is required to examine the effects of the induction of labour at this gestation on the fetal outcome.
authors.affiliation: Maternity Department, Northwick Park Hospital, Harrow, Middlesex, England.
authors.forename: M J
authors.initials: MJ
authors.lastname: Turner
authors.forename: R
authors.initials: R
authors.lastname: Fox
authors.forename: M
authors.initials: M
authors.lastname: Brassil
authors.forename: R
authors.initials: R
authors.lastname: Gleeson
authors.forename: H
authors.initials: H
authors.lastname: Gordon
mesh_terms: D000282:Administration, Intravaginal; D015232:Dinoprostone / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007751:Labor, Induced / Q000379:methods*; D010298:Parity / Q000187:drug effects*; D011247:Pregnancy; D012307:Risk Factors; D013607:Tablets; D013997:Time Factors
chemical_list: D013607:Tablets; D015232:Dinoprostone