title: Effect of weaning, week postweaning and diet composition on pancreatic and small intestinal luminal lipase response in young swine.
abstract: The effects of weaning, week postweaning and diet composition on concentration of lipase in the pancreas and small intestinal lumen were investigated in weanling swine. In Exp. 1, lipase levels were evaluated in suckling pigs from 2 to 35 d of age and in pigs weaned at 21 or 35 d of age. Pigs weaned at 21 d of age were fed a corn-soybean meal diet with lipase levels measured from 3 to 28 d postweaning. Pancreas weights increased during the suckling period; they were lowered at 3 d postweaning and were lower at 7 d postweaning than in suckling pigs but increased linearly from 3 to 28 d postweaning. Lipase level per unit wet tissue and total pancreatic levels increased from 2 to 35 d of age in suckling pigs (P less than .01). Weaning at 21 d of age resulted in a decline (P less than .05) in lipase levels in the pancreas at 3 and 7 d postweaning, but the levels subsequently tended to increase between 7 and 28 d postweaning. Whereas relative lipase levels in the intestinal lumen increased from 2 to 35 d of age in suckling pigs, total luminal enzyme did not decline upon weaning when pigs were weaned at either 21 or 35 d of age. Total luminal lipase per unit empty body increased linearly (P less than .01) each week postweaning. In Exp. 2, a 2 X 2 factorial arrangement of corn oil (0 or 6%) and dried whey (0 or 25%) was used to evaluate digestive lipase levels in pigs weaned at 21 d of age.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Ohio State University, Columbus.
authors.forename: K R
authors.initials: KR
authors.lastname: Cera
authors.forename: D C
authors.initials: DC
authors.lastname: Mahan
authors.forename: G A
authors.initials: GA
authors.lastname: Reinhart
mesh_terms: D000821:Animal Feed; D000818:Animals; D000833:Animals, Suckling / Q000254:growth & development / Q000378:metabolism; D001835:Body Weight; D004032:Diet; D007421:Intestine, Small / Q000201:enzymology*; D008049:Lipase / Q000096:biosynthesis*; D009929:Organ Size; D010179:Pancreas / Q000201:enzymology*; D013552:Swine / Q000254:growth & development / Q000378:metabolism*; D014886:Weaning
chemical_list: D008049:Lipase