title: [Can tumors of the breast larger than 3 centimeters be treated conservatively?].
abstract: Unlike small breast cancers, which are now treated conservatively by primary tumorectomy, the most important lesions (T2 and T3) as usually treated tumorectomy, the most important lesions (T2 and T3) as usually treated by mastectomy. However, in patients with these large lesions attempts may be made at conserving the breast with reliable oncological safety and good cosmetic results. Depending on clinical presentation, one or the other of two therapeutic approaches may be considered. The most common treatment is preoperative radiotherapy of 45 Gy which, in more than 50 p. 100 of the cases results in a tumoral regression that is sufficient for secondary tumorectomy to be performed. In some patients, the first-line treatment consists of wide tumoral excision as part of a reductive mammaplasty, followed by radiation.
authors.affiliation: Département interhospitalier de cancérologie, hôpital Henri-Mondor, Créteil.
authors.forename: E
authors.initials: E
authors.lastname: Calitchi
authors.forename: F
authors.initials: F
authors.lastname: Feuilhade
authors.forename: Y
authors.initials: Y
authors.lastname: Otmezguine
authors.forename: B
authors.initials: B
authors.lastname: Brun
authors.forename: P
authors.initials: P
authors.lastname: Piedbois
authors.forename: M
authors.initials: M
authors.lastname: Julien
authors.forename: J
authors.initials: J
authors.lastname: Baruch
authors.forename: J P
authors.initials: JP
authors.lastname: Le Bourgeois
authors.forename: B
authors.initials: B
authors.lastname: Pierquin
mesh_terms: D001943:Breast Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008408:Mastectomy / Q000379:methods*; D011300:Preoperative Care; D011829:Radiation Dosage; D016019:Survival Analysis
vernacular_title: Peut-on être conservateur pour les tumeurs du sein supérieures à 3 centimètres?