Erythrocyte fatty acid profiles in childhood malignancy.
The erythrocyte fatty acid composition was determined for 79 children using gas chromatography. The stearic:oleic acid ratio (SOR) was significantly lower in those children with newly diagnosed malignancies than in a reference group of healthy children. However, a control group of children with chronic, non-malignant conditions were also found to have a low SOR. These results suggest that the erythrocyte SOR cannot be used as a tumour marker in children.
Heard
W
W
Department of Child Health, Southampton General Hospital, England, UK.
Kohler
J A
JA
Postle
A D
AD
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002849:Chromatography, Gas; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009369:Neoplasms / Q000097:blood*; D009829:Oleic Acids / Q000097:blood*; D013229:Stearic Acids / Q000097:blood*
D009829:Oleic Acids; D013229:Stearic Acids