Jejunal water and sodium secretion occurs in chronic idiopathic intestinal pseudo-obstruction.
We observed jejunal water and sodium secretion in two patients with chronic idiopathic intestinal pseudo-obstruction by standard perfusion techniques. The ability of glucose to reverse this secretory state was impaired. These observations suggest that a jejunal secretory state may contribute to the diarrhea in chronic idiopathic intestinal pseudo-obstruction.
Rolston
D D
DD
Department of Gastroenterology, St. Bartholomew's Hospital, West Smithfield, London, U.K.
Hunt
J B
JB
Fairclough
P D
PD
Wilks
M
M
Levison
D A
DA
Clark
M L
ML
Farthing
M J
MJ
D000328:Adult; D001834:Body Water / Q000378:metabolism*; D002908:Chronic Disease; D003967:Diarrhea / Q000150:complications; D005260:Female; D005947:Glucose / Q000502:physiology; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000150:complications / Q000378:metabolism* / Q000503:physiopathology; D007552:Isotonic Solutions / Q000493:pharmacokinetics; D007583:Jejunum / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism*
D007552:Isotonic Solutions; D012964:Sodium; D005947:Glucose