title: 5q deletion. The sole chromosome change in a carcinoma of the bladder.
abstract: Direct chromosome preparations of a transitional cell carcinoma of the bladder that had invaded the mucosa but not more deeply showed a 46,XY,5q- karyotype in nearly all metaphases. This is the first description of a 5q deletion, which may have been interstitial, del(5)(q13q22), as the only change in a bladder carcinoma.
authors.affiliation: Department of Cancer Research, Mount Vernon Hospital, Northwood, Middlesex, England.
authors.forename: N B
authors.initials: NB
authors.lastname: Atkin
authors.forename: M F
authors.initials: MF
authors.lastname: Fox
mesh_terms: D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000235:genetics / Q000473:pathology; D002872:Chromosome Deletion; D002895:Chromosomes, Human, Pair 5; D006801:Humans; D007621:Karyotyping; D008297:Male; D001749:Urinary Bladder Neoplasms / Q000235:genetics* / Q000473:pathology