title: Anterior temporal lobectomy for complex partial seizures: evaluation, results, and long-term follow-up in 100 cases.
abstract: We report evaluation and results in 100 patients who had undergone anterior temporal lobectomy for intractable complex partial seizures. Average follow-up was 9.0 years (range, 2 to 21 years). In the 2nd postoperative year, 63% were seizure free, 16% were significantly improved, and 21% were considered not significantly improved. Mean number of seizures in the last group was 27% of preoperative levels. Surgical results did not change significantly in subsequent postoperative years; good outcomes tended to persist over the longer term. We also examined the utility of continuous depth electrode monitoring in the evaluation of patients with independent bitemporal interictal epileptiform activity. Despite limited numbers of subjects in this category, there was a trend toward improved surgical outcome when such subjects were evaluated with depth electrodes.
authors.affiliation: Department of Medicine, Duke University Medical Center, Durham, NC 27710.
authors.forename: T S
authors.initials: TS
authors.lastname: Walczak
authors.forename: R A
authors.initials: RA
authors.lastname: Radtke
authors.forename: J O
authors.initials: JO
authors.lastname: McNamara
authors.forename: D V
authors.initials: DV
authors.lastname: Lewis
authors.forename: J S
authors.initials: JS
authors.lastname: Luther
authors.forename: E
authors.initials: E
authors.lastname: Thompson
authors.forename: W P
authors.initials: WP
authors.lastname: Wilson
authors.forename: A H
authors.initials: AH
authors.lastname: Friedman
authors.forename: B S
authors.initials: BS
authors.lastname: Nashold
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography / Q000379:methods; D004833:Epilepsy, Temporal Lobe / Q000503:physiopathology / Q000601:surgery*; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011184:Postoperative Period; D011379:Prognosis; D011446:Prospective Studies; D013702:Temporal Lobe / Q000601:surgery*