title: Lesion patterns of vasoactive intestinal polypeptide-containing neurons in the myenteric plexus induced by clamping or transsection of rat jejunum.
abstract: The acute reactions of vasoactive intestinal polypeptide (VIP)-containing neurons in the myenteric plexus of the rat jejunum in response to circumferential clamping or transection/reanastomosis were evaluated in a detailed time course of up to ten days. Whereas in sham-operated controls VIP immunostaining was confined exclusively to varicose fibers, either clamping or transection induced the appearance of strongly VIP-immunoreactive beaded neuronal processes and neuronal perikarya in the oral part of the lesion one day postoperatively. After five days strongly immunostained varicose fibers orientated in the longitudinal axis of the gut towards the lesion reappeared suggestive of the onset of regenerative processes.
authors.affiliation: Anatomical Institute, Department Neuroanatomy, Munich, F.R.G.
authors.forename: P
authors.initials: P
authors.lastname: Trudrung
authors.forename: H
authors.initials: H
authors.lastname: Waldner
authors.forename: J
authors.initials: J
authors.lastname: Sklarek
authors.forename: C
authors.initials: C
authors.lastname: Nitsch
mesh_terms: D000818:Animals; D005260:Female; D007150:Immunohistochemistry; D007583:Jejunum / Q000294:innervation* / Q000378:metabolism / Q000601:surgery; D009197:Myenteric Plexus / Q000378:metabolism* / Q000601:surgery; D051381:Rats; D011919:Rats, Inbred Strains; D014660:Vasoactive Intestinal Peptide / Q000378:metabolism*
chemical_list: D014660:Vasoactive Intestinal Peptide