title: [An aggressive angiomyxoma of the vulva].
abstract: A case of an aggressive angiomyxoma of the vulva in a 38-year-old lady is reported. The tumor was gelatinous and 12 x 8 x 7 cm in size. Histologically, spindle or stellate-shaped tumor cells and blood vessels were found distributed in a myxoid stroma. It was found that the tumor cells were immunoreactive to vimentin but negative to desmin and smooth muscle specific actin. Ultrastructurally the tumor cells had an intercellular junction, an abundant, rough endemic reticulum, and intracytoplasmic filaments, but no focal densities of the filaments and the basal lamina. These findings have revealed that this tumor consisted of myofibroblastic cells resembling fibroblasts rather than myofibroblasts.
authors.affiliation: Dept. of Pathology, Hamamatsu Univ. School of Med.
authors.forename: M
authors.initials: M
authors.lastname: Maeda
authors.forename: S
authors.initials: S
authors.lastname: Baba
authors.forename: I
authors.initials: I
authors.lastname: Kosugi
authors.forename: H
authors.initials: H
authors.lastname: Shirasawa
authors.forename: T
authors.initials: T
authors.lastname: Fujishiro
mesh_terms: D000328:Adult; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007382:Intermediate Filaments / Q000648:ultrastructure; D008854:Microscopy, Electron; D009232:Myxoma / Q000473:pathology* / Q000648:ultrastructure; D014846:Vulvar Neoplasms / Q000473:pathology* / Q000648:ultrastructure