title: SequenceEditingAligner: a multiple sequence editor and aligner.
abstract: Here we present the SequenceEditingAligner system for editing multiple, aligned genetic sequences. This is an interactive multi-window color system that displays more than 3500 nucleotides or amino acids. The system handles nucleic acid or protein sequences with or without secondary structure data. More than 300 sequences, each more than 1500 elements in length, may be analyzed together. With the system scientists can classify elements, align sequences, edit them, find consensus patterns, and simultaneously generate oligomer frequency histograms and other statistics.
authors.affiliation: Laboratory of Mathematical Biology, National Cancer Institute, Frederick, MD 21701-1013.
authors.forename: A M
authors.initials: AM
authors.lastname: Barber
authors.forename: J V
authors.initials: JV
authors.lastname: Maizel
mesh_terms: D000465:Algorithms; D000595:Amino Acid Sequence; D001483:Base Sequence; D003196:Computer Graphics; D004247:DNA / Q000235:genetics*; D007256:Information Systems; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D011487:Protein Conformation; D011506:Proteins / Q000235:genetics; D012984:Software
chemical_list: D011506:Proteins; D004247:DNA