Neonatal polycythaemia: effect of partial dilutional exchange transfusion with human albumin on whole blood viscosity.
Haematocrit (HCT) and viscosity of whole blood were measured in ten polycythaemic hyperviscous newborn infants both before and after dilutional partial exchange transfusion with 5% albumin. This was performed in order to evaluate the effect on the lowering of HCT and whole blood viscosity. Mean umbilical HCT values decreased from 68.7% before, to 54.4% post transfusion. This decrease in HCT and viscosity was highly significant (P less than 0.001). Safety and lack of complications make human albumin solution superior to human plasma for exchange transfusion in neonatal polycythaemia.
Levy
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I
Department of Neonatology, Beilinson Medical Centre, Petah Tiqva, Israel.
Merlob
P
P
Ashkenazi
S
S
Reisner
S H
SH
D001798:Blood Proteins / Q000627:therapeutic use*; D001809:Blood Viscosity; D006801:Humans; D007231:Infant, Newborn; D010951:Plasma Exchange; D010952:Plasma Substitutes / Q000627:therapeutic use*; D011086:Polycythemia / Q000097:blood / Q000628:therapy*; D012709:Serum Albumin / Q000627:therapeutic use*; D000075462:Serum Albumin, Human; D012712:Serum Globulins
D001798:Blood Proteins; D010952:Plasma Substitutes; D012709:Serum Albumin; D012712:Serum Globulins; C008930:plasma protein fraction; D000075462:Serum Albumin, Human