title: Facilitated ERG recovery in taurine-treated bovine eyes, an ex vivo study.
abstract: Excorporal bovine eye with stable ERG patterns were used in this study to examine the possible antihypoxic property of the taurine. Taurine (1 mM) given prior to or after the on-set of hypoxia facilitated the retinal recovery as indicated by the B-wave amplitude changes. This observation is consistent with previous observations in hippocampal slice and other tissues which suggests an antihypoxic function of this sulfur-containing amino acid.
authors.affiliation: Department of Anatomical Sciences and Neurobiology, School of Medicine, University of Louisville, KY 40292.
authors.forename: M T
authors.initials: MT
authors.lastname: Tseng
authors.forename: K N
authors.initials: KN
authors.lastname: Liu
authors.forename: N R
authors.initials: NR
authors.lastname: Radtke
mesh_terms: D000818:Animals; D002417:Cattle; D005260:Female; D000860:Hypoxia / Q000188:drug therapy / Q000503:physiopathology*; D066298:In Vitro Techniques; D008564:Membrane Potentials; D010775:Photic Stimulation; D012160:Retina / Q000187:drug effects / Q000502:physiology*; D013654:Taurine / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D013654:Taurine