Radiation associated eosinophilia and monocytosis in carcinoma of the uterine cervix: a simple reliable clinical and prognostic indicator.
Clinical and prognostic significance of radiation associated eosinophilia (RAE) and radiation associated monocytosis (RAM) was evaluated in 176 patients with squamous cell carcinoma of the uterine cervix followed up after radiotherapy. Significant RAE was noticed in patients with Stages I/IIA and IIB who remained disease-free after treatment. On the contrary, patients belonging to these two stages but who developed recurrent disease showed absence of RAE. These patients as well as those belonging to Stage III showed considerably higher levels of RAM as compared to those patients remaining disease-free. These observations showed the usefulness of these two simple inexpensively carried out parameters in prognosticating disease course in malignant cervical neoplasia.
Radhakrishna Pillai
M
M
Regional Cancer Centre, Trivandrum, India.
Balaram
P
P
Bindu
S
S
Hareendran
N K
NK
Padmanabhan
T K
TK
Nair
M K
MK
D002294:Carcinoma, Squamous Cell / Q000276:immunology / Q000532:radiotherapy*; D004802:Eosinophilia / Q000209:etiology*; D005260:Female; D006801:Humans; D007964:Leukocytosis / Q000209:etiology*; D009000:Monocytes / Q000528:radiation effects*; D009367:Neoplasm Staging; D011379:Prognosis; D011878:Radiotherapy / Q000009:adverse effects*; D002583:Uterine Cervical Neoplasms / Q000276:immunology / Q000532:radiotherapy*