Altromycins, novel pluramycin-like antibiotics. II. Isolation and elucidation of structure.
A novel complex of Gram-positive antibiotics was produced from the fermentation of an actinomycete culture AB 1246E-26. The antibiotics were recovered from the whole fermentation broth by extraction with organic solvent and isolated using counter-current chromatography. UV and IR data place these compounds in the anthraquinone-derived class of antibiotics. Mass spectral and NMR data indicate a new complex of compounds related to, but distinctly different from the pluramycin type antibiotics.
Brill
G M
GM
Anti-infective Research Division, Abbott Laboratories, IL 60064.
McAlpine
J B
JB
Whittern
D N
DN
Buko
A M
AM
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000032:analysis / Q000302:isolation & purification*; D002845:Chromatography; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; C063716:altromycin A; C063718:altromycin C; C063717:altromycin B; C063719:altromycin D