A human alpha satellite DNA subset specific for chromosome 12.
We have isolated a DNA clone (pBR12, locus D12Z3) which identifies an alphoid subset specific for chromosome 12. This alphoid subset has an EcoRI periodicity of 680 bp and is characterized by a higher-order repeat of about 1.4 kb (eight basic units of about 170 bp each) as revealed by several restriction enzymes. The sequence analysis confirmed the alphoid nature of pBR12 and the dimeric organization.
Baldini
A
A
Department of Molecular Biology and Genetics, Wayne State University, Detroit, MI 48201.
Rocchi
M
M
Archidiacono
N
N
Miller
O J
OJ
Miller
D A
DA
D015139:Blotting, Southern; D002881:Chromosomes, Human, Pair 12; D004247:DNA / Q000235:genetics; D004276:DNA, Satellite / Q000235:genetics*; D005819:Genetic Markers; D006801:Humans; D012091:Repetitive Sequences, Nucleic Acid
D004276:DNA, Satellite; D005819:Genetic Markers; D004247:DNA