Radiation-induced esophageal cancer: a case report and a review of the literature.
A 63 year old woman who had been irradiated for thyroid carcinoma at 36 years of age developed a cervico-esophageal stricture, the biopsy specimens from which revealed squamous cell carcinoma. Total esophagectomy was performed and a small linear ulcer was found in the resected specimen. Histological examination revealed moderately differentiated squamous cell carcinoma with severe fibrosis around the tumor, indicating radiation-induced cervical esophageal cancer. The characteristics of radiation-induced esophageal cancers described in the literature are reviewed in context of the present case.
Shimizu
T
T
First Department of Surgery, Tottori University School of Medicine, Yonago, Japan.
Matsui
T
T
Kimura
O
O
Maeta
M
M
Koga
S
S
D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology; D004938:Esophageal Neoplasms / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000473:pathology*