title: Taurine in normal and diseased human skeletal muscle.
abstract: Taurine content of 199 clinical muscle biopsies was determined and correlated to histometric data of 121 cases. Taurine concentration in muscles was markedly dependent on fiber type distribution, taurine being more abundant in the slow, oxidative type 1 fibers than in the type 2 fibers. Taurine concentration rose slightly with age and tended to be higher in denervations, muscular dystrophies and myotonias, but the differences from the control values were non-significant.
authors.affiliation: Department of Paediatrics, University of Kuopio, Finland.
authors.forename: E M
authors.initials: EM
authors.lastname: Airaksinen
authors.forename: L
authors.initials: L
authors.lastname: Paljärvi
authors.forename: J
authors.initials: J
authors.lastname: Partanen
authors.forename: Y
authors.initials: Y
authors.lastname: Collan
authors.forename: R
authors.initials: R
authors.lastname: Laakso
authors.forename: T
authors.initials: T
authors.lastname: Pentikäinen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000473:pathology; D009132:Muscles / Q000378:metabolism* / Q000473:pathology; D009135:Muscular Diseases / Q000378:metabolism* / Q000473:pathology; D009468:Neuromuscular Diseases / Q000378:metabolism* / Q000473:pathology; D013654:Taurine / Q000378:metabolism*
chemical_list: D013654:Taurine