title: Tooth pulp changes following Le Fort I maxillary osteotomy in a primate model.
abstract: Le Fort I maxillary 'down-fracture' osteotomy with 8 mm advancement was performed in 15 adult rhesus monkeys. Forty-five tooth pulps were examined histologically at intervals from 0 to 24 weeks after surgery. Cell degeneration occurred in 31% of pulps examined, necrosis in 16% of pulps and osteo-dentine was found in 7% of pulps. Almost half of the teeth examined (47%) showed marked cellular changes, more frequently found in posterior teeth. Other features noted were inflammation (13%) and reactive dentine in pulps (24%). Axons degenerated initially but recovered by 24 weeks. It is concluded that Le Fort I maxillary osteotomy caused pulpal disturbances in an animal model and the extent to which this occurs in patients needs to be carefully monitored.
authors.affiliation: Department of Oral Surgery and Oral Pathology, Birmingham Dental School.
authors.forename: R M
authors.initials: RM
authors.lastname: Browne
authors.forename: C L
authors.initials: CL
authors.lastname: Brady
authors.forename: J W
authors.initials: JW
authors.lastname: Frame
mesh_terms: D000818:Animals; D001864:Bone Wires; D003790:Dental Pulp Necrosis / Q000209:etiology* / Q000473:pathology; D003809:Dentin, Secondary / Q000473:pathology*; D005260:Female; D008253:Macaca mulatta; D008437:Maxilla / Q000601:surgery*; D010027:Osteotomy / Q000009:adverse effects*; D011671:Pulpitis / Q000209:etiology* / Q000473:pathology; D013997:Time Factors