The association of serum proteins with preeclampsia.
In 239 pregnant women, 107 with preeclampsia and 132 controls, phenotype frequency distribution of serum group-specific component (Gc) and haptoglobin (Hp) was studied by disc-electrophoresis in polyacrylamide gel. The results demonstrate a significant statistical difference in phenotype frequency distribution of the Gc-system. Gc 2-1 phenotype was expressed significantly in women with preeclampsia compared to controls. Gc 2-1 phenotype may be useful as a genetic marker for early detection of preeclampsia.
Mekbeb
T
T
Yekatit 12 Hospital, Department of Obstetrics and Gyneacology, Addis Ababa, Ethiopia.
D005260:Female; D005819:Genetic Markers; D006242:Haptoglobins / Q000235:genetics*; D006801:Humans; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D012307:Risk Factors; D014809:Vitamin D-Binding Protein / Q000235:genetics*
D005819:Genetic Markers; D006242:Haptoglobins; D014809:Vitamin D-Binding Protein