[Furosemide capsules in the treatment of hypertension or heart failure in the elderly in general practice].
The article reports the efficacy and tolerability of a new slow-release formulation of furosemide (Lasix Retard) given to an elderly (mean: 72 years, range 48-92) population (n = 115, 77 females) suffering from hypertension or heart failure. In 34 of 52 patients with heart failure the clinical condition improved. Lasix Retard reduced blood pressure significantly from 187/99 to 166/93 after one year on 30 mg/day (n = 19). It was found that Lasix Retard replaces thiazide diuretics without causing any significant change in blood pressure. There were no significant changes in metabolic indicators (S-potassium, S-urate, S-glucose). Side effects were in the same range as reported for thiazide diuretics. There were 33 (29%) drop-outs.
Terland
O
O
D000368:Aged; D003692:Delayed-Action Preparations / Q000627:therapeutic use; D005260:Female; D005665:Furosemide / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged
D003692:Delayed-Action Preparations; D005665:Furosemide
Furosemidkapsler i behandlingen av hypertensjon eller hjertesvikt hos eldre i allmennpraksis.