title: [Antibiotic therapy of nosocomial infections in children].
abstract: The choice of antibiotics for the treatment of hospital-acquired infections in children is a rational choice based on the child's general condition, on the site of infection, on the most probable pathogens and on their current sensitivity to antibiotics. The antibiotic chosen must reach bactericidal concentrations at the site of infection for rapid reduction or the inoculum and to limit the systemic spread of infection, thereby decreasing the risk of a rapidly expanding infectious process in the younger children. The optimal antibiotic is selected on the basis of what is known about bacterial resistance. General therapeutic rules must be adjusted to the epidemiological situation prevailing in each hospital department.
authors.affiliation: Laboratoire de bactériologie, hôpital Robert-Debré, Paris.
authors.forename: E
authors.initials: E
authors.lastname: Bingen
authors.forename: N
authors.initials: N
authors.lastname: Lambert-Zechovsky
authors.forename: J C
authors.initials: JC
authors.lastname: Mercier
authors.forename: F
authors.initials: F
authors.lastname: Beaufils
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy*; D002648:Child; D003428:Cross Infection / Q000188:drug therapy*; D004352:Drug Resistance, Microbial; D004756:Enterobacteriaceae Infections / Q000188:drug therapy; D006801:Humans; D011552:Pseudomonas Infections / Q000188:drug therapy; D013203:Staphylococcal Infections / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: L'antibiothérapie des infections nosocomiales de l'enfant.