Cholecystocolonic fistula: malabsorptive consequences of lost bile acids.
A patient with the painless onset of a cholecystocolonic fistula associated with virtually complete common bile duct obstruction due to stones provided a unique opportunity to assess the consequences of prolonged bile acid depletion on the digestion and absorption of nutrients. Over 2 years, the patient insidiously developed steatorrhea, osteomalacia with an atraumatic pelvic fracture, and congestive heart failure complicated by polymorphic ventricular tachycardia (torsade de pointes) all of which could be attributed to malabsorption of fat and fat-soluble vitamins.
Benage
D
D
Department of Medicine, Indiana University School of Medicine, Indianapolis.
O'Connor
K W
KW
D000368:Aged; D001647:Bile Acids and Salts / Q000172:deficiency*; D001658:Biliary Fistula / Q000150:complications / Q000378:metabolism*; D002769:Cholelithiasis / Q000150:complications / Q000378:metabolism*; D003108:Colonic Diseases / Q000150:complications / Q000378:metabolism*; D005260:Female; D005705:Gallbladder Diseases / Q000150:complications / Q000378:metabolism*; D006801:Humans; D007412:Intestinal Fistula / Q000150:complications / Q000378:metabolism*; D008286:Malabsorption Syndromes / Q000209:etiology
D001647:Bile Acids and Salts