Successful pregnancy following bone marrow transplantation for leukaemia.
We report three pregnancies with successful outcomes in two women following allogeneic bone marrow transplantation (BMT) for acute leukaemia using high dose melphalan alone as conditioning therapy. The increasing application and success of BMT together with the instigation of conditioning regimens that do not include total body irradiation should increase such cases. These and previous cases document that a normal outcome of pregnancy is likely in these patients.
Milliken
S
S
Leukaemia Unit, Royal Marsden Hospital, Sutton, UK.
Powles
R
R
Parikh
P
P
Whitehead
M
M
Mayes
I
I
Prentice
A
A
Falconer
A
A
Aboud
H
H
Helenglass
G
G
Nandi
A
A
D000328:Adult; D016026:Bone Marrow Transplantation; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy / Q000601:surgery*; D008558:Melphalan / Q000627:therapeutic use*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000188:drug therapy / Q000601:surgery*; D012074:Remission Induction
D008558:Melphalan