[C-peptide, diabetogenic factor and the blood anticoagulating system in patients with the insulin-dependent type of diabetes mellitus before and after heparin therapy].
The authors analyzed the results of investigation of insulin residual secretion determined by the concentration of C-peptide in response to the stimulation of 1 mg of glucagon. The blood level of the diabetogenic factor (DGF) and activity of the anticoagulative system (ACS) were studied in parallel in patients with insulin-dependent type of diabetes mellitus before and after heparin therapy. The blood DGF disappeared, ACS function was restored, and the patient's body resistance to blood hypercoagulation developed against a background of heparin therapy. A decrease in insulin residual secretion was shown to be related to a duration of diabetes mellitus.
Balabolkin
M I
MI
Kudriashov
B A
BA
Levitskaia
Z I
ZI
Liapina
L A
LA
Ul'ianov
A M
AM
D000293:Adolescent; D000328:Adult; D001777:Blood Coagulation / Q000187:drug effects / Q000502:physiology*; D002096:C-Peptide / Q000097:blood* / Q000187:drug effects; D002648:Child; D002908:Chronic Disease; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000188:drug therapy; D005260:Female; D005934:Glucagon; D006493:Heparin / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010907:Pituitary Hormones / Q000097:blood*; D013997:Time Factors
D002096:C-Peptide; D010907:Pituitary Hormones; C010912:diabetogenic factor, human; D006493:Heparin; D005934:Glucagon
C-peptid, diabetogennyĭ faktor i protivosvertyvaiushchaia sistema krovi u bol'nykh insulinzavisimym tipom sakharnogo diabeta do i posle geparinoterapii.