title: [Hemophagocytic syndrome in two elderly men].
abstract: Case 1: A 68-year-old male, who was admitted to our hospital because of massive intestinal bleeding, died 1 day after admission. Case 2: An 80-year-old male, who was admitted to our hospital because of a loss of consciousness, died 4 days after admission. In both cases prodromic infection was not detected. At autopsy, phagocytosis of RBC and WBC by histiocytes was shown markedly in the spleen in case 1 and in the bone marrow in case 2. So diagnosis of virus-associated hemophagocytic syndrome was made. It might be related to some underlying immunologic derangement, because both cases were in advanced age.
authors.affiliation: Department of Internal Medicine, Koseiren Tyuusei General Hospital.
authors.forename: T
authors.initials: T
authors.lastname: Nakase
authors.forename: K
authors.initials: K
authors.lastname: Morita
authors.forename: M
authors.initials: M
authors.lastname: Tomeoku
authors.forename: M
authors.initials: M
authors.lastname: Katou
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001853:Bone Marrow / Q000473:pathology; D015616:Histiocytosis, Non-Langerhans-Cell / Q000209:etiology / Q000473:pathology*; D006801:Humans; D008297:Male; D013154:Spleen / Q000473:pathology; D014777:Virus Diseases / Q000150:complications