[Gadolinium-DTPA in the study of intracranial tumors in the adult].
Thirty intracranial tumours were explored by MRI, using T1- and T2-weighted sequences, before and after intravenous injection of Gd-DTPA. Two-thirds of the intra-axial tumours were accurately detected on one section plane by MRI without Gd-DTPA, but in one quarter of the cases Gd-DTPA only delineated precisely the tumour. On the other hand, Gd-DTPA failed to detect certain tumours (benign gliomas) or showed only a small part of them (mixed grade gliomas), while they were detected by MRI without contrast injection. However, in such cases Gd-DTPA was useful for the stereotaxic biopsy of the tumour. Gd-DTPA appears of lesser interest in extra-axial tumours. Gd-DTPA is thus valuable for the neuroradiological diagnosis of brain tumours, particularly to evaluate the grade of gliomas and to confirm the diagnosis of recurrent growths.
Grégoire
N
N
Service de Neuroradiologie Clinique et Experimentale CHU, La Timone, Marseille.
Momose
T
T
Rumeau
C
C
Perot
S
S
Girard
N
N
Lavanga
A
A
Salamon
G
G
D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000601:surgery; D002493:Central Nervous System Diseases / Q000175:diagnosis / Q000473:pathology; D005260:Female; D019786:Gadolinium DTPA; D005910:Glioma / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D009942:Organometallic Compounds; D004369:Pentetic Acid
D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA
Apport du gadolinium-DTPA à l'étude des tumeurs intracrâniennes de l'adulte.