Factors associated with conjunctival intraepithelial neoplasia: a case control study.
Familial and environmental factors may play a role in the development of conjunctival intraepithelial neoplasia (CIN). Nineteen patients with biopsy-proven CIN completed a questionnaire to evaluate possible predisposing factors. Nineteen age-matched and sex-matched controls completed questionnaires and received slit-lamp examinations. Factors associated with a relatively increased risk of developing CIN included exposure to petroleum products, heavy cigarette smoking, light hair and ocular pigmentation, and family origin in the British Isles, Austria or Switzerland. Non-office and nonprofessional workers were more likely to develop conjunctival intraepithelial neoplasia (p = .05), as were those who were not college graduates (p = .07).
Napora
C
C
Cornea Service, Wills Eye Hospital, Philadelphia, Pa. 19107.
Cohen
E J
EJ
Genvert
G I
GI
Presson
A C
AC
Arentsen
J J
JJ
Eagle
R C
RC
Laibson
P R
PR
D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D003230:Conjunctival Neoplasms / Q000453:epidemiology* / Q000208:ethnology / Q000209:etiology / Q000235:genetics; D004522:Educational Status; D004781:Environmental Exposure; D004848:Epithelium; D005127:Eye Color; D005260:Female; D006200:Hair Color; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000453:epidemiology; D012307:Risk Factors; D011795:Surveys and Questionnaires