Congenital absence of the corticospinal fibers: pathologic and clinical observations.
We describe 2 patients with primary absence of corticospinal tracts. Both presented with delayed motor development, head lag, and spasticity of the limbs. We could not identify precentral cortex, and there were no corticospinal fibers below the internal capsules. We postulate that the fibers were displaced or interrupted early in their development.
Roessmann
U
U
Division of Neuropathology, Case Western Reserve University, Cleveland, OH 44106.
Horwitz
S J
SJ
Kennell
J H
JH
D001921:Brain / Q000473:pathology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011712:Pyramidal Tracts / Q000002:abnormalities* / Q000473:pathology