title: Neuroblastoma in a patient with Sotos' syndrome.
abstract: Sotos' syndrome, or cerebral gigantism, is a disorder of growth regulation. Tumours have occasionally been reported in children with Sotos' syndrome, but it is uncertain whether this is a coincidence, or whether it is aetiologically related to the underlying disorder of growth. We report a 15 month old child with a paraspinal neuroblastoma and Sotos' syndrome and suggest that children with this condition may be at higher risk for developing tumours than the general population.
authors.affiliation: Department of Pediatrics, University of Minnesota, Minneapolis 55455.
authors.forename: M A
authors.initials: MA
authors.lastname: Nance
authors.forename: J P
authors.initials: JP
authors.lastname: Neglia
authors.forename: D
authors.initials: D
authors.lastname: Talwar
authors.forename: S A
authors.initials: SA
authors.lastname: Berry
mesh_terms: D005147:Facial Bones / Q000002:abnormalities; D005260:Female; D005877:Gigantism / Q000150:complications*; D006130:Growth Disorders / Q000150:complications*; D006801:Humans; D006972:Hypertelorism; D007223:Infant; D009447:Neuroblastoma / Q000175:diagnosis / Q000209:etiology*; D013125:Spinal Neoplasms / Q000175:diagnosis / Q000209:etiology*; D013577:Syndrome