title: Acute disseminated encephalomyelitis. MRI findings and the distinction from multiple sclerosis.
abstract: Brain MRI was performed on 12 patients with acute disseminated encephalomyelitis (ADEM). Multifocal white matter lesions indistinguishable from those seen in multiple sclerosis (MS) were found in 10. In 5 there were rather extensive symmetric abnormalities in the cerebral (2) or cerebellar white matter (2), or basal ganglia (1). Follow-up MRI after intervals of 2 wks to 18 months demonstrated partial resolution of the abnormalities, but some persisting lesions. New MRI lesions were found at follow-up in only 1 case after an interval of 2 wks. Serial MRI makes a useful contribution to the distinction between MS and ADEM.
authors.affiliation: Multiple Sclerosis NMR Research Group, Institute of Neurology, Queen Square, London, UK.
authors.forename: J
authors.initials: J
authors.lastname: Kesselring
authors.forename: D H
authors.initials: DH
authors.lastname: Miller
authors.forename: S A
authors.initials: SA
authors.lastname: Robb
authors.forename: B E
authors.initials: BE
authors.lastname: Kendall
authors.forename: I F
authors.initials: IF
authors.lastname: Moseley
authors.forename: D
authors.initials: D
authors.lastname: Kingsley
authors.forename: E P
authors.initials: EP
authors.lastname: du Boulay
authors.forename: W I
authors.initials: WI
authors.lastname: McDonald
mesh_terms: D000208:Acute Disease; D000328:Adult; D001921:Brain / Q000473:pathology; D003937:Diagnosis, Differential; D004679:Encephalomyelitis / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009103:Multiple Sclerosis / Q000175:diagnosis*