title: Immunoreactive circulating alpha-interferon is low in Sjögren's syndrome.
abstract: Circulating alpha-interferon in plasma of 26 patients with Sjögren's syndrome was 0.069 +/- 0.034 ng/ml, a significant decrease compared with 0.119 +/- 0.051 ng/ml for age- and sex-matched healthy subjects (P less than 0.01) and compared with values previously found for healthy donors at ages 1-89 years. The results indicate the inability of Sjögren's syndrome patients to maintain circulating alpha-interferon.
authors.affiliation: Department of Medicine, Kobe University School of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Shiozawa
authors.forename: K
authors.initials: K
authors.lastname: Shiozawa
authors.forename: S
authors.initials: S
authors.lastname: Shimizu
authors.forename: Y
authors.initials: Y
authors.lastname: Tanaka
authors.forename: I
authors.initials: I
authors.lastname: Morimoto
authors.forename: R
authors.initials: R
authors.lastname: Yoshihara
authors.forename: Y
authors.initials: Y
authors.lastname: Kuroki
authors.forename: M
authors.initials: M
authors.lastname: Hashimoto
authors.forename: T
authors.initials: T
authors.lastname: Fujita
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007370:Interferon Type I / Q000097:blood*; D008875:Middle Aged; D011863:Radioimmunoassay; D012016:Reference Values; D012859:Sjogren's Syndrome / Q000097:blood*
chemical_list: D007370:Interferon Type I