Lomefloxacin (SC-47111 or NY-198). Comparative antimicrobial activity against 2002 clinical isolates from hospitals in Mexico City.
A new difluorinated quinolone, lomefloxacin, was shown to have potent in vitro activity against a broad spectrum of bacteria, including multiresistant strains isolated from patients with severe infections in three hospitals in Mexico City. Whereas its activity was comparable to that of another fluoroquinolone (enoxacin), the pharmacokinetic advantages offered by lomefloxacin may be a significant benefit in clinical use.
Durazo
F
F
Hospital Mocel, Mexico City, Mexico.
Resano
F
F
Gonzalez
M A
MA
D042462:4-Quinolones; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D001424:Bacterial Infections / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D024841:Fluoroquinolones; D006801:Humans; D008800:Mexico; D008826:Microbial Sensitivity Tests; D015363:Quinolones
D042462:4-Quinolones; D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D015363:Quinolones; C053091:lomefloxacin