title: A simple method for measuring patient anti-globulin responses against isotypic or idiotypic determinants.
abstract: A simple inhibition of capture enzyme-linked immunosorbent assay (IOC-ELISA) was developed which permitted the independent measurement of anti-idiotypic and anti-isotypic antiglobulins in serum samples from patients receiving therapeutic monoclonal antibodies.
authors.affiliation: Department of Pathology, Cambridge University, U.K.
authors.forename: S P
authors.initials: SP
authors.lastname: Cobbold
authors.forename: P R
authors.initials: PR
authors.lastname: Rebello
authors.forename: H F
authors.initials: HF
authors.lastname: Davies
authors.forename: P J
authors.initials: PJ
authors.lastname: Friend
authors.forename: M R
authors.initials: MR
authors.lastname: Clark
mesh_terms: D000888:Antibodies, Anti-Idiotypic / Q000032:analysis*; D001710:Biotin; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007132:Immunoglobulin Isotypes / Q000276:immunology*
chemical_list: D000888:Antibodies, Anti-Idiotypic; D007132:Immunoglobulin Isotypes; D001710:Biotin