title: [Colonic neoplasms and skin fibromas: common determinants and their significance].
abstract: To find common factors for colonic-neoplasias and skin-tags, 157 inpatients, who consecutively had a coloscopy because of intestinal complaints, were intensively examined dermatologically. Regression-analyses showed that the number of colonic polyps were age- (p = 3 x 10(-8)) and sex-dependent (1.9 x 10(-2)) and skin-tags had no influence on the number of colonic polyps. The size of colonic polyps also showed a clear age dependency (p = 3 x 10(-8)). The number of skin-tags were dependent on weight (p = 9 x 10(-3)) and age (p = 1.3 x 10(-2)), its size on the interaction of sex and triglyceride-levels (p = 3 x 10(-8)). Discriminant-analyses identified the following factors as important: age and triglyceride-concentration to recognize a patient with colonic polyps; age, positive Haemoccult-test and number of skin-tags to recognize a patient with tubulovillous adenomas or colonic carcinomas. The essential common factor of colonic polyps and skin-tags was the age. For the recognition of a patient with colonic polyps the age was the most essential factor, skin-tags, on the contrary, were unimportant. The association between colonic polyps and skin-tags therefore was merely an effect of age.
authors.affiliation: I. Medizinische Klinik des St. Markus-Krankenhauses, Frankfurt/M.
authors.forename: A
authors.initials: A
authors.lastname: Leopolder-Ochsendorf
authors.forename: F R
authors.initials: FR
authors.lastname: Ochsendorf
authors.forename: K H
authors.initials: KH
authors.lastname: Tews
authors.forename: R
authors.initials: R
authors.lastname: Milbradt
authors.forename: P
authors.initials: P
authors.lastname: Herzog
authors.forename: K H
authors.initials: KH
authors.lastname: Holtermüller
mesh_terms: D000367:Age Factors; D002784:Cholesterol / Q000097:blood; D003110:Colonic Neoplasms / Q000209:etiology*; D003111:Colonic Polyps / Q000209:etiology*; D005260:Female; D005350:Fibroma / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000209:etiology*; D009780:Occult Blood; D010257:Paraneoplastic Syndromes / Q000209:etiology*; D012307:Risk Factors; D012878:Skin Neoplasms / Q000209:etiology*; D014280:Triglycerides / Q000097:blood
chemical_list: D014280:Triglycerides; D002784:Cholesterol
vernacular_title: Kolonneoplasien und Hautfibrome: Gemeinsame Einflussgrössen und deren Bedeutung.