Low frequency Raman spectra of Z-DNA.
We have performed a Raman study of the low frequency modes in three oligo- and polynucleotides in Z-conformation, and we compare the spectra of these samples to those of two polynucleotides in B-conformation. In Z-DNA we find 5 intrahelical modes below 200 cm-1, in addition to the interhelical mode near 30 cm-1 which is only observed in crystalline samples. The most prominent intrahelical mode has a frequency of about 105 cm-1, close to the frequency of the strongest intrahelical mode in A-and B-DNA. The sequence dependence of the frequency of this mode is considerably larger than for the same mode in B-DNA. The other modes are less pronounced, and their frequency variations with base sequence are within the experimental accuracy.
Weidlich
T
T
Physics Department, Arizona State University, Tempe 85287.
Lindsay
S M
SM
Peticolas
W L
WL
Thomas
G A
GA
D001483:Base Sequence; D003460:Crystallization; D004247:DNA; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides; D011089:Polydeoxyribonucleotides; D013059:Spectrum Analysis, Raman
D009838:Oligodeoxyribonucleotides; D011089:Polydeoxyribonucleotides; C031156:poly d(I-C); C019530:poly(dC-dG); C029988:poly(dG-m(5)dC).poly(dG-m(5)dC); D004247:DNA