Clostridium difficile-associated diarrhea after norfloxacin.
Although theoretically the spectrum of antimicrobial quinolone antibiotics are at low risk of producing Clostridium difficile overgrowth and diarrhea, a patient developed this clinical problem while receiving norfloxacin. We review the antimicrobial activity of the quinolone antibiotics, with respect to their predisposition for producing C. difficile-induced diarrhea.
Ehrenpreis
E D
ED
Department of Medicine, Northwestern University Medical School, Chicago, Illinois.
Lievens
M W
MW
Craig
R M
RM
D000368:Aged; D003015:Clostridium Infections / Q000139:chemically induced* / Q000150:complications; D003967:Diarrhea / Q000139:chemically induced* / Q000150:complications; D005759:Gastroenteritis / Q000188:drug therapy; D006801:Humans; D008297:Male; D009643:Norfloxacin / Q000009:adverse effects* / Q000627:therapeutic use
D009643:Norfloxacin