title: [Hyperprostaglandin E syndrome in a nine-year-old child].
abstract: The authors describe the history of a nine year old girl, with a disease that seemed to be hyperprostaglandin-E syndrome. They give a survey of the literature about the pathophysiological cause of the disease, the clinical and laboratory findings and the effect of indomethacin, which can inhibit the synthesis of prostaglandins. Prolonged treatment with indomethacin can decrease the urinary excretion of prostaglandine, polyuria and hypercalciuria and it can moderate the growth retardation. They found the same but milder clinical and laboratory features at the four year old brother of the patient too.
authors.affiliation: Baranya Megyei Tanács Gyermekkórháza, Pécs.
authors.forename: E
authors.initials: E
authors.lastname: Kollmann
authors.forename: H W
authors.initials: HW
authors.lastname: Seyberth
authors.forename: E
authors.initials: E
authors.lastname: Sulyok
mesh_terms: D002118:Calcium / Q000652:urine; D002648:Child; D005260:Female; D006130:Growth Disorders / Q000150:complications; D006801:Humans; D007213:Indomethacin / Q000494:pharmacology / Q000627:therapeutic use*; D008607:Intellectual Disability / Q000150:complications; D011141:Polyuria / Q000150:complications; D011458:Prostaglandins E / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000652:urine*; D013577:Syndrome
chemical_list: D011458:Prostaglandins E; D002118:Calcium; D007213:Indomethacin
vernacular_title: Kilencéves gyermek hyperprostaglandin-E syndromája.