Insulin-dependent diabetes mellitus associated with danazol.
Insulin-dependent diabetes mellitus developed in a young woman 8 weeks after the initiation of danazol for treatment of pelvic endometriosis. After discontinuation of danazol the diabetes completely resolved. We suspect a possible cause-and-effect relationship, which has not previously been reported in the literature.
Seifer
D B
DB
Department of Obstetrics and Gynecology, State University of New York Health Science Center, Syracuse.
Freedman
L N
LN
Cavender
J R
JR
Baker
R A
RA
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D003613:Danazol / Q000009:adverse effects*; D003922:Diabetes Mellitus, Type 1 / Q000139:chemically induced*; D004715:Endometriosis / Q000188:drug therapy; D005260:Female; D006801:Humans; D011245:Pregnadienes / Q000009:adverse effects*; D011247:Pregnancy
D001786:Blood Glucose; D011245:Pregnadienes; D003613:Danazol