title: [Essential blepharospasm and botulinum toxin. An electrophysiologic study].
abstract: Thirty-five patients with essential blepharospasm were investigated electrophysiologically after local treatment with subcutaneous periocular injections of botulinum toxin. In all patients the blink reflex was measured on both sides. The results showed in some cases reproducible changes in the reflexes, indicating a central supranuclear origin for the spasm. Furthermore, an influence of afferent information on the "spasm threshold" via the trigeminal nerve is suggested.
authors.affiliation: Universitäts-HNO-Klinik, Göttingen.
authors.forename: R
authors.initials: R
authors.lastname: Laskawi
authors.forename: W
authors.initials: W
authors.lastname: Damenz
authors.forename: P
authors.initials: P
authors.lastname: Roggenkämper
authors.forename: M
authors.initials: M
authors.lastname: Schröder
authors.forename: J
authors.initials: J
authors.lastname: Brauneis
mesh_terms: D001764:Blepharospasm / Q000188:drug therapy*; D001905:Botulinum Toxins / Q000008:administration & dosage*; D005071:Evoked Potentials / Q000187:drug effects; D005141:Eyelid Diseases / Q000188:drug therapy*; D005143:Eyelids / Q000294:innervation*; D005154:Facial Nerve / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D009431:Neural Conduction / Q000187:drug effects*; D011930:Reaction Time / Q000187:drug effects; D012018:Reflex / Q000187:drug effects*; D014276:Trigeminal Nerve / Q000187:drug effects
chemical_list: D001905:Botulinum Toxins
vernacular_title: Essentieller Blepharospasmus und Botulinus-Toxin. Eine elektrophysiologische Untersuchung.