title: [Xenodiagnosis using Lutzomyia youngi in Venezuelan cases of cutaneous leishmaniasis due to Leishmania braziliensis].
abstract: Eight patients infected with Leishmania braziliensis were used for xenodiagnosis with Lutzomyia youngi, before and after specific antileishmanial treatment with "glucantime" and "gabbromycin". All of them infected sandflies fed on the borders of the skin lesions before the treatment, suggesting that infected persons might act as reservoirs of infection for an indoor-biting sandfly species. The negative results obtained by xenodiagnosis carried out after specific treatment of the same individuals indicated cure of the patients, and a reduction of risk for further intradomiciliary transmission.
authors.affiliation: Centro de Investigaciones Jose W. Torrealba, Trujillo, Venezuela.
authors.forename: E
authors.initials: E
authors.lastname: Rojas
authors.forename: J V
authors.initials: JV
authors.lastname: Scorza
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000965:Antimony / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004197:Disease Reservoirs; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D007896:Leishmaniasis / Q000188:drug therapy / Q000469:parasitology / Q000635:transmission*; D008297:Male; D008536:Meglumine / Q000627:therapeutic use; D000077485:Meglumine Antimoniate; D009942:Organometallic Compounds / Q000627:therapeutic use; D011576:Psychodidae / Q000469:parasitology* / Q000472:pathogenicity / Q000502:physiology
chemical_list: D009942:Organometallic Compounds; D008536:Meglumine; D000077485:Meglumine Antimoniate; D000965:Antimony
vernacular_title: Xenodiagnostico con Lutzomyia youngi en casos venezolanos de leishmaniasis cutanea por Leishmania braziliensis.