title: Neuroradiologic findings in leptomeningeal carcinomatosis: the value interest of gadolinium-enhanced MRI.
abstract: Four patients with leptomeningeal metastases documented by neuroradiological examinations are reported. All had central nervous system or systemic neoplasms and showed clinical signs of carcinomatous meningitis. Gadolinium-enhanced MRI (Gd-MRI) disclosed for each patient pathological foci, allowing delineation of the extent of meningeal disease. Although non-specific, these findings, combined with the clinical context and CSF analysis, may lead to a rapid diagnosis and treatment of carcinomatous meningitis, even when malignant cells are not detected in the cerebrospinal fluid.
authors.affiliation: Department of Neuroradiology, Hôpital Erasme, Université Libre de Bruxelles, Belgium.
authors.forename: G
authors.initials: G
authors.lastname: Rodesch
authors.forename: P
authors.initials: P
authors.lastname: Van Bogaert
authors.forename: N
authors.initials: N
authors.lastname: Mavroudakis
authors.forename: P M
authors.initials: PM
authors.lastname: Parizel
authors.forename: J J
authors.initials: JJ
authors.lastname: Martin
authors.forename: C
authors.initials: C
authors.lastname: Segebarth
authors.forename: M
authors.initials: M
authors.lastname: Van Vyve
authors.forename: D
authors.initials: D
authors.lastname: Baleriaux
authors.forename: J
authors.initials: J
authors.lastname: Hildebrand
mesh_terms: D000328:Adult; D000368:Aged; D001932:Brain Neoplasms; D002648:Child; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D008175:Lung Neoplasms; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000556:secondary*; D008579:Meningioma / Q000175:diagnosis / Q000556:secondary*; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid
chemical_list: D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA