[Antimicrobial action of new imidazolinium compounds].
Syntheses and antibacterial activity of 1-ethyl-2-alkyl-3-(alkoxymethyl)- and 1-ethyl-2-alkyl-3-(alkylthiomethyl)imidazolinium chlorides are described. Syntheses of the imidazolinium compounds were performed by reaction of 1-ethyl-2-alkylimidazoline with chloromethylalkyl ether or with chloromethylalkyl sulfide. Antimicrobial properties of obtained compounds was tested on 13 strains of bacteria and fungi. Chlorides with alkylthiomethyl residue showed the highest antimicrobial activity.
Kuncewicz
Z
Z
Institut für Chemische Technologie der Technischen Universität, Poznań, Polen.
Krysiński
J
J
Pernak
J
J
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis*; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D002851:Chromatography, High Pressure Liquid; D004755:Enterobacteriaceae / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D007093:Imidazoles / Q000032:analysis / Q000138:chemical synthesis* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D007093:Imidazoles
Antimikrobielle Wirkung neuer Imidazoliniumverbindungen.