Changes in parathyroid hormone in diabetic patients on long-term hemodialysis.
Changes in parathyroid hormone (PTH) and osteocalcin over 3 years were studied in hemodialyzed patients with diabetic nephropathy (HD/DM) and hemodialyzed patients without diabetes (HD/non-DM). In HD/DM patients, concentrations of the carboxyl terminal regions of PTH and osteocalcin in the serum did not change significantly, but in HD/non-DM patients, both concentrations increased significantly. In patients in both groups, the mean concentration of the mid-region of PTH increased significantly. Secondary hyperparathyroidism in HD/DM develops slower than in HD/non-DM.
Kikunami
K
K
Inoue Hospital, Suita, Japan.
Nishizawa
Y
Y
Tabata
T
T
Nakatsuka
K
K
Matsushita
Y
Y
Inoue
T
T
Miki
T
T
Morii
H
H
D005260:Female; D006030:Glycosuria, Renal / Q000097:blood*; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000097:blood; D008297:Male; D008875:Middle Aged; D015675:Osteocalcin / Q000097:blood*; D010281:Parathyroid Hormone / Q000097:blood*; D006435:Renal Dialysis; D013997:Time Factors
D010281:Parathyroid Hormone; D015675:Osteocalcin