title: Lymphoproliferation in captive wild ruminants affected with malignant catarrhal fever: 25 cases (1977-1985).
abstract: The severity of lymphoproliferative disease associated with malignant catarrhal fever was extremely variable among 25 animals at the San Diego Wild Animal Park. Severe lymphoproliferative disease was seen in 3 of 10 Formosan Sika deer (Cervus nippon taiouanus), 3 of 6 Indian Axis deer (Cervus a axis), 3 of 6 Barasingha deer (Cervus d duvauceli), and 1 of 3 Nilgai (Boselaphus tragocamelus). Two Sika deer and 2 Barasingha deer had lesions morphologically indistinguishable from lymphosarcoma. Our findings were consistent with the hypothesis that alcelaphine herpesvirus-1 has oncogenic potential.
authors.affiliation: Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada.
authors.forename: J E
authors.initials: JE
authors.lastname: Blake
authors.forename: N O
authors.initials: NO
authors.lastname: Nielsen
authors.forename: W P
authors.initials: WP
authors.lastname: Heuschele
mesh_terms: D000367:Age Factors; D000818:Animals; D000836:Animals, Zoo; D003670:Deer; D005260:Female; D006564:Herpesviridae / Q000302:isolation & purification; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology / Q000662:veterinary; D008232:Lymphoproliferative Disorders / Q000453:epidemiology / Q000209:etiology / Q000662:veterinary*; D008297:Male; D008304:Malignant Catarrh / Q000150:complications*; D012418:Ruminants; D013997:Time Factors