[An analysis of the cellular DNA contents in lung-metastasized stomach cancers].
A study has been conducted of the cellular DNA contents in the primary and metastatic lesions of 30 cases of lung-metastasized stomach cancers, in which each DNA Index (DI) was calculated and analysed comparatively. As a consequence, the rate of the diploid type in the nodular lung metastases was found to be higher than the rate of the others. Further, the DI's of 22 out of 30 (73%) metastatic lymph nodes corresponded with those of the primary lesions. Four lung metastatic lesions out of five differed from their primary lesions, but all five lesions simulated their metastatic lymph nodes. Thus understanding of the properties of the metastatic lymph nodes, rather than their primary lesions, would seen to be helpful in planning the therapy to combat recurrent cancers.
Umehara
Y
Y
1st Dept. of Surgery, Hamamatsu Univ. School of Med.
Miyahara
T
T
Yoshida
M
M
Oba
N
N
Matsuda
T
T
Gotou
H
H
Harada
Y
Y
D000782:Aneuploidy; D004273:DNA, Neoplasm / Q000032:analysis*; D004171:Diploidy; D005434:Flow Cytometry; D006801:Humans; D008175:Lung Neoplasms / Q000032:analysis / Q000401:mortality / Q000556:secondary*; D008198:Lymph Nodes / Q000032:analysis / Q000473:pathology; D008207:Lymphatic Metastasis; D011379:Prognosis; D013274:Stomach Neoplasms / Q000032:analysis* / Q000401:mortality / Q000473:pathology; D015996:Survival Rate
D004273:DNA, Neoplasm