title: Free jejunal interposition graft for reconstruction of the esophagus.
abstract: Forty-seven patients underwent pharyngoesophageal reconstruction using a free jejunal interposition graft (FJIG) at Duke University Medical Center from 1978 through 1987. There were 30 men and 17 women with ages ranging from 38 to 87 years old (mean age, 64 years). Twenty-one patients (group A) had no prior surgical procedures, 20 (group B) were reconstructed following radiation and/or surgical failure, with 6 patients (group C) having benign strictures of the upper alimentary tract. Follow-up ranged up to 122 months (mean, 23 months), with 3 patients lost to follow-up, and 4 perioperative deaths (within 3 months of surgery). There were a total of 9 initial graft failures, 4 patients undergoing successful re-implantation, resulting in an overall success rate of 89% (42 of 47). Excluding patients with graft failures, perioperative deaths, and patients lost to follow-up, 33 of 36 patients with a viable FJIG were able to maintain adequate swallowing function yielding a physiologic success rate of 86%. All of the 21 patients dying of recurrent disease had excellent palliation with the FJIG. Of the 7 patients who are alive, only 1 has dysphagia secondary to stricture. In conclusion, it is felt that the FJIG is a sophisticated method of reconstructing large surgical defects of the pharyngoesophagus with a high technical and physiologic success rate.
authors.affiliation: Department of Surgery, Duke University Medical Center, Durham, NC 27710.
authors.forename: S R
authors.initials: SR
authors.lastname: Fisher
authors.forename: R
authors.initials: R
authors.lastname: Cameron
authors.forename: D J
authors.initials: DJ
authors.lastname: Hoyt
authors.forename: T B
authors.initials: TB
authors.lastname: Cole
authors.forename: H F
authors.initials: HF
authors.lastname: Seigler
authors.forename: W C
authors.initials: WC
authors.lastname: Meyers
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004940:Esophageal Stenosis / Q000601:surgery; D004944:Esophagoplasty / Q000401:mortality; D005260:Female; D006084:Graft Rejection; D006085:Graft Survival; D006258:Head and Neck Neoplasms / Q000601:surgery; D006801:Humans; D007583:Jejunum / Q000637:transplantation*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010611:Pharyngectomy / Q000401:mortality; D011183:Postoperative Complications / Q000453:epidemiology / Q000401:mortality; D012086:Reoperation