[Microtests for evaluating hemostasis and their clinical value].
A system of microtests, adapted for pediatric practice, has been developed, tested, and proposed for practical use. The system includes 13 microtests, 4 of them meet the requirements of a rapid diagnostic test, the others are used as differentiating and specifying. For the first time three levels of the coagulation status have been distinguished in the newborn: physiologic, border and pathologic; this enables orientation in hemorrhagic and thrombohemorrhagic diseases in the newborn. On the basis of the unified microtests the authors have determined the tactics in early diagnosis and follow-up of newborns suffering from hemorrhage treated outpatiently. The diagnosis was verified under dispensary conditions in 158 (66.6%) children with hemorrhagic diathesis. The results of the investigations described are promising for further improvement of the diagnosis and treatment of hemostasis disorders in newborns with the use of the microtests of new generation.
Barkagan
L Z
LZ
Chuprova
A V
AV
Doroshenko
L A
LA
D001777:Blood Coagulation / Q000187:drug effects / Q000502:physiology*; D001780:Blood Coagulation Tests / Q000379:methods*; D002675:Child, Preschool; D006474:Hemorrhagic Disorders / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007231:Infant, Newborn
D006490:Hemostatics
Mikrotesty otsenki gemostaza i ikh klinicheskoe znachenie.