[The effect of oxytocin, prostenon and obzidan on uterine contractile activity in pregnant rats].
The results of experimental pharmacological studies may help obstetricians to make a choice of a schedule of using the uterotropic drugs and their doses. In vivo and in vitro experiments on pregnant rats showed that administration of the Soviet-made prostaglandin E2--prostenon--in combination with oxytocin and obsidan in half doses increased its stimulating effect on the myometrium. The use of prostenon and oxytocin against the background of partusisten treatment was not followed by a significant change of their stimulating uterotropic action.
Korkhov
V V
VV
Sulukhiia
R V
RV
Makusheva
V P
VP
Mats
M N
MN
D000818:Animals; D015232:Dinoprostone / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D005260:Female; D066298:In Vitro Techniques; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D010121:Oxytocin / Q000494:pharmacology*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects* / Q000502:physiology; D011433:Propranolol / Q000494:pharmacology*; D051381:Rats; D013997:Time Factors; D014590:Uterine Contraction / Q000187:drug effects* / Q000502:physiology
D010121:Oxytocin; D011433:Propranolol; D015232:Dinoprostone
Vliianie oksitotsina, prostenona i obzidana na sokratitel'nuiu aktivnost' matki beremennykh krys.