Autoimmune hemolytic anemia in Gaucher's disease.
A 23-year-old Ashkenazi woman with Gaucher's disease developed Coombs-positive warm-type autoimmune hemolytic anemia. Treatment with high-dose steroids resulted in complete remission within 2 weeks. Study of an additional 72 patients with Gaucher's disease revealed another case of Coombs-positive warm-type autoimmune hemolytic anemia; other autoimmune disorders were found in 17 of these patients. The possible association of Coombs-positive hemolytic anemia and Gaucher's disease is discussed.
Haratz
D
D
Department of Medicine, Hadassah University Hospital, Jerusalem, Israel.
Manny
N
N
Raz
I
I
D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000175:diagnosis / Q000235:genetics*; D002869:Chromosome Aberrations / Q000175:diagnosis / Q000235:genetics*; D025063:Chromosome Disorders; D003298:Coombs Test; D005260:Female; D005776:Gaucher Disease / Q000175:diagnosis / Q000235:genetics*; D005808:Genes, Recessive; D006801:Humans; D012307:Risk Factors