title: [Course of pregnancy and labor following in vitro fertilization. A retrospective study of 246 deliveries].
abstract: This record concerns the statistical registration and analysis of the courses and developments having taken place in 246 pregnancies and births after in-vitro-fertilization. The cases were registered retrospectively, the degree of registration being 77.2% approximately; the scientific evaluation was carried out on the basis of the BPE 1987. It can be shown that there is an increased incidence of the EPH-gestosis, the clinically relevant placenta insufficiency syndrome, the intrauterine death of fetus, the abruptio placentae and prematurity. As predisposing factors must primarily be seen and discussed the ovarian hyperstimulation being--in most cases--connected with IVF and the higher age of the patients; it can be supposed that the method of fertilization in vitro itself is of minor importance. Its importance in the pathogenesis of abruptio placentae, however, cannot be exactly evaluated so far. The frequency of multiple pregnancies represents a special problem. Though the rate is lower in the examined group than in comparable--that is due to the limited number of collected oocytes--it should be aimed at a further lowering of multiple pregnancy rates.
authors.affiliation: Abteilung für Sterilitätsdiagnostik und in-vitro-Fertilisation, Frauenklinik Dr. Krüsmann.
authors.forename: K
authors.initials: K
authors.lastname: Fiedler
authors.forename: W
authors.initials: W
authors.lastname: Würfel
authors.forename: G
authors.initials: G
authors.lastname: Krüsmann
authors.forename: M
authors.initials: M
authors.lastname: Rothenaicher
authors.forename: P
authors.initials: P
authors.lastname: Hirsch
authors.forename: W
authors.initials: W
authors.lastname: Krüsmann
mesh_terms: D000328:Adult; D004624:Embryo Transfer; D005113:Extraction, Obstetrical; D005260:Female; D005307:Fertilization in Vitro; D005317:Fetal Growth Retardation / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D007744:Obstetric Labor Complications / Q000209:etiology*; D007752:Obstetric Labor, Premature / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology*; D011272:Pregnancy, Multiple; D012189:Retrospective Studies; D012307:Risk Factors
vernacular_title: Zum Schwangerschafts- und Geburtsverlauf nach In-Vitro-Fertilisation (IVF). Eine retrospektive Untersuchung nach 246 Entbindungen.