title: Terminal deletions of the long arm of chromosome 7: five new cases.
abstract: Twenty-two cases of terminal deletions of the long arm of chromosome 7 have been reported. We present 5 new cases, 3 of which were ascertained due to fetal holoprosencephaly, one due to anencephaly, and one due to multiple structural defects in a 15-year-old boy. The presence of holoprosencephaly in 3 of the 5 cases reported herein and in 2 previously reported cases suggests that this manifestation may be commonly observed in individuals with deletion 7q.
authors.affiliation: Department of Medicine, University of California, San Diego 92093.
authors.forename: M H
authors.initials: MH
authors.lastname: Bogart
authors.forename: C
authors.initials: C
authors.lastname: Cunniff
authors.forename: C
authors.initials: C
authors.lastname: Bradshaw
authors.forename: K L
authors.initials: KL
authors.lastname: Jones
authors.forename: O W
authors.initials: OW
authors.lastname: Jones
mesh_terms: D000015:Abnormalities, Multiple / Q000196:embryology / Q000235:genetics*; D000293:Adolescent; D001921:Brain / Q000002:abnormalities; D002871:Chromosome Banding; D002872:Chromosome Deletion; D002897:Chromosomes, Human, Pair 7; D005260:Female; D005333:Fetus / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011296:Prenatal Diagnosis