title: Plasma amino acids in term neonates and infants with phenylketonuria before and after institution of the diet.
abstract: The plasma amino acid concentrations were measured in 12 neonates with phenylketonuria (PKU). Blood samples were taken when fasting and two hours after a meal. The individual amino acid concentrations, the glycine/valine ratios, and the total amino acid concentrations were mutually compared and also compared to reference intervals. When the diet was instituted and plasma phenylalanine decreased, we observed a normalization of the postprandial response of isoleucine, leucine, tyrosine, and valine.
authors.affiliation: John F. Kennedy Institute, Glostrup, Denmark.
authors.forename: A M
authors.initials: AM
authors.lastname: Gerdes
authors.forename: J B
authors.initials: JB
authors.lastname: Nielsen
authors.forename: H
authors.initials: H
authors.lastname: Lou
authors.forename: F
authors.initials: F
authors.lastname: Güttler
mesh_terms: D000596:Amino Acids / Q000097:blood*; D005215:Fasting / Q000097:blood; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010649:Phenylalanine / Q000009:adverse effects; D010661:Phenylketonurias / Q000097:blood* / Q000178:diet therapy; D013997:Time Factors
chemical_list: D000596:Amino Acids; D010649:Phenylalanine