Trisomy 4 in a case of acute undifferentiated myeloblastic leukemia with hand-mirror cells.
A case of acute undifferentiated myelocytic leukemic with trisomy 4 is described. The patient is a 61-year-old woman who developed leukemia 4 1/2 years after receiving radiation therapy for uterine carcinoma. Many leukemic cells exhibited hand-mirror configuration after the bone marrow aspirate was left at room temperature overnight. The relationship between trisomy 4 and hand-mirror cells in acute myelocytic leukemia is unknown.
Kao
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YS
Department of Pathology, Louisiana State University Medical Center, New Orleans 70112-1393.
McCormick
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Vial
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D001856:Bone Marrow Examination; D002894:Chromosomes, Human, Pair 4; D005260:Female; D006801:Humans; D007621:Karyotyping; D015479:Leukemia, Myelomonocytic, Acute / Q000209:etiology / Q000235:genetics* / Q000473:pathology; D008875:Middle Aged; D014314:Trisomy; D014594:Uterine Neoplasms / Q000532:radiotherapy