title: [Clinical course and prognosis in T-cell lymphoblastic tumors in children typed with Soviet-produced monoclonal antibodies].
abstract: Correlation analysis of the clinical course and prognosis was made in 56 children with T-cell lymphoblastic tumors (acute lymphoblastic leukemia and lymphosarcoma) typed with the use of monoclonal antibodies obtained in this country. The frequency of T-cell marker detection among all immunological subvariants in acute lymphoid leukemia and lymphosarcoma proved to be similar (36.6 and 37%, respectively). In acute lymphoid leukemia type T1 of tumor cells prevailed (58%), while in lymphosarcoma type T3 (63%). T2 and T3-cell lymphoblastic tumors were characterized by the most severe clinical course.
authors.forename: L A
authors.initials: LA
authors.lastname: Makhonova
authors.forename: S A
authors.initials: SA
authors.lastname: Maiakova
authors.forename: G A
authors.initials: GA
authors.lastname: Gordina
authors.forename: N N
authors.initials: NN
authors.lastname: Tupitsyn
authors.forename: A V
authors.initials: AV
authors.lastname: Kiselev
authors.forename: I S
authors.initials: IS
authors.lastname: Peterson
authors.forename: I E
authors.initials: IE
authors.lastname: Gavrilova
authors.forename: E I
authors.initials: EI
authors.lastname: Moiseenko
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Baryshnikov
mesh_terms: D000293:Adolescent; D000911:Antibodies, Monoclonal; D000970:Antineoplastic Agents / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D004351:Drug Resistance; D005260:Female; D006801:Humans; D007223:Infant; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D007958:Leukocyte Count; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D008297:Male; D011379:Prognosis; D012074:Remission Induction; D013601:T-Lymphocytes / Q000276:immunology*; D014586:USSR
chemical_list: D000911:Antibodies, Monoclonal; D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor
vernacular_title: Klinicheskoe techenie i prognoz T-kletochnykh limfoblastnykh opukholeĭ u deteĭ, tipirovannykh otechestvennymi monoklonal'nymi antitelami.