title: Intravesical dimethyl sulfoxide instillations in the treatment of secondary amyloidosis of the bladder.
abstract: A-22-year-old woman with long-standing rheumatoid arthritis and secondary amyloidosis of the bladder had recurrent profuse macroscopic hematuria. She was treated with intravesical dimethyl sulfoxide instillation every 2 weeks for 1 year. She remained asymptomatic during the treatment and at 6 months. Progressive disappearance of amyloid from the superficial mucosa of the bladder was demonstrated in sequential histological examinations.
authors.affiliation: Department of Surgery, University of Turku, Finland.
authors.forename: M J
authors.initials: MJ
authors.lastname: Nurmi
authors.forename: T O
authors.initials: TO
authors.lastname: Ekfors
authors.forename: P O
authors.initials: PO
authors.lastname: Rajala
authors.forename: P V
authors.initials: PV
authors.lastname: Puntala
mesh_terms: D000283:Administration, Intravesical; D000328:Adult; D000686:Amyloidosis / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D004121:Dimethyl Sulfoxide / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D006417:Hematuria / Q000150:complications; D006801:Humans; D001745:Urinary Bladder Diseases / Q000150:complications / Q000188:drug therapy* / Q000473:pathology
chemical_list: D004121:Dimethyl Sulfoxide