[Determination of cerebral blood flow using an 81Rb/81mKr generator system].
A method is being developed which not only measures cerebral blood flow as a static quantity but also its changes with time. For that purpose a semiconductor device ascertains the proportion of intracerebral 81 Rb and 81mKr activities. By opening the hemato-encephalic barrier in animal experiments a sufficient concentration of intracerebral 81 Rb could be attained and the modified blood circulation after step-wise ligature of all brain arteries brought into relation to the corresponding Rb/Kr quotient. Over the range from undisturbed to completely interrupted cerebral blood flow this quotient varied up to 25% of its initial value.
Schroth
H J
HJ
Abteilung für Nuklearmedizin und med. Physik der Med, Fakultät, Universitätsklinik des Saarlandes Homburg/Saar, Bundesrepublik Deutschland.
Bialy
J
J
Hans
F J
FJ
Oberhausen
E
E
Peters
J W
JW
Schmitt
M
M
Warnke
P
P
D000818:Animals; D001812:Blood-Brain Barrier; D002560:Cerebrovascular Circulation; D004285:Dogs; D007727:Krypton Radioisotopes; D009994:Osmolar Concentration; D011817:Rabbits; D011876:Radionuclide Generators; D012414:Rubidium Radioisotopes; D012996:Solutions
D007727:Krypton Radioisotopes; D012414:Rubidium Radioisotopes; D012996:Solutions
Bestimmung des zerebralen Blutflusses mittels des 81Rb/81mKr-Generatorsystems.