title: Carcinoma of the nasal vestibule: report of 12 cases.
abstract: Carcinoma of the nasal vestibule has an individual clinical character; in this retrospective analysis the data of 12 consecutive patients are reported. Small lesions were treated by surgical resection and larger tumours by intra-arterial chemotherapy (IAC) followed by external beam radiotherapy. One patient had a recurrence which was successfully treated surgically; six had previous or subsequent malignancies. The results of the most recent series reported in the literature are reviewed and the rationale of the IAC approach is discussed. The reported treatment policy seems effective in achieving the highest cure rate with the best functional results.
authors.affiliation: Division of Otolaryngology, General Hospital, Pordenone, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Barzan
authors.forename: G
authors.initials: G
authors.lastname: Franchin
authors.forename: S
authors.initials: S
authors.lastname: Frustaci
authors.forename: A
authors.initials: A
authors.lastname: De Paoli
authors.forename: R
authors.initials: R
authors.lastname: Comoretto
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery; D012189:Retrospective Studies