title: Stress-induced increase in noradrenaline release in the rat hypothalamus assessed by intracranial microdialysis.
abstract: The hypothalamic microdialysis of conscious rats was used to investigate the effects of immobilization stress (20 min) on extracellular noradrenaline (NA) levels. The stress significantly increased NA levels relative to basal efflux by 106% and this elevation continued for 40 min after release from stress.
authors.affiliation: Department of Pharmacology, Kurume University School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Yokoo
authors.forename: M
authors.initials: M
authors.lastname: Tanaka
authors.forename: T
authors.initials: T
authors.lastname: Tanaka
authors.forename: A
authors.initials: A
authors.lastname: Tsuda
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid; D003956:Dialysis / Q000379:methods; D005110:Extracellular Space / Q000378:metabolism; D007032:Hypothalamus, Anterior / Q000378:metabolism*; D008297:Male; D009638:Norepinephrine / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012149:Restraint, Physical; D013312:Stress, Physiological / Q000378:metabolism / Q000503:physiopathology*; D013997:Time Factors
chemical_list: D009638:Norepinephrine