Endogenous Listeria monocytogenes endophthalmitis presenting as keratouveitis.
We report a case of Listeria monocytogenes endophthalmitis that presented as a recalcitrant keratouveitis in a nonimmunocompromized patient. L. monocytogenes was recovered from the patient's aqueous, vitreous, and two of three blood cultures. He was treated with topical, subconjunctival, and systemic antibiotics, but the visual outcome was poor, possibly because of late diagnosis. A review of previous cases of L. monocytogenes endophthalmitis demonstrates unique features of this infection: (a) presentation as an anterior uveitis or keratouveitis with elevated intraocular pressure, (b) endogenous origin, and (c) frequent occurrence in nonimmunocompromized patients.
Heidemann
D G
DG
Department of Ophthalmology, William Beaumont Hospital, Royal Oak, Michigan.
Trese
M
M
Murphy
S F
SF
Bradford
D
D
Lewis
M
M
Dunn
S P
SP
D000368:Aged; D000667:Ampicillin / Q000627:therapeutic use; D002437:Cefazolin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D009877:Endophthalmitis / Q000175:diagnosis* / Q000188:drug therapy; D015818:Eye Infections, Bacterial / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007634:Keratitis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008088:Listeriosis / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D014605:Uveitis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D014792:Visual Acuity
D000667:Ampicillin; D002437:Cefazolin