title: Comparison of TestPack and Ovustick for predicting ovulation.
abstract: A study was designed to compare two methods of predicting the time of ovulation by detection of the urinary luteinizing hormone (LH) surge with two immunoassay kits designed for home use. A newly developed kit, TestPack, was compared with an existing kit, Ovustick. A group of 20 women with regular cycles were studied for one menstrual cycle. Ovulation was established with a serum LH surge and disappearance of the dominant follicle using transvaginal sonography followed by a rise in the serum progesterone level. In the 20 subjects, presumptive evidence of ovulation was obtained by determining the LH surge and the subsequent progesterone peak. In 18 of the 20, disappearance of the dominant follicle was also documented. Ovulation was predicted in 17 of the 20 subjects by both TestPack and Ovustick. Both tests were effective in predicting the day of ovulation, but TestPack provided a more easily defined end point and required less time and effort to perform.
authors.affiliation: Department of Obstetrics and Gynecology, University of Southern California School of Medicine, Los Angeles.
authors.forename: M H
authors.initials: MH
authors.lastname: Rodriquez
authors.forename: D R
authors.initials: DR
authors.lastname: Mishell
authors.forename: C
authors.initials: C
authors.lastname: Grozinger
authors.forename: J N
authors.initials: JN
authors.lastname: Cao
authors.forename: M
authors.initials: M
authors.lastname: Lacarra
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D007986:Luteinizing Hormone / Q000652:urine; D006080:Ovarian Follicle / Q000502:physiology; D010061:Ovulation Detection / Q000379:methods*; D011374:Progesterone / Q000097:blood
chemical_list: D011374:Progesterone; D007986:Luteinizing Hormone