title: Successful treatment of acquired pendular elliptical nystagmus in multiple sclerosis with isoniazid and base-out prisms.
abstract: We treated 3 multiple sclerosis patients who had pendular nystagmus with isoniazid (800 to 1,000 mg/d). Isoniazid abolished the nystagmus and relieved oscillopsia in 2 patients but was ineffective in the 3rd in whom the nystagmus was damped with convergence and vision improved with converging (base-out) prisms.
authors.affiliation: Neurological Clinic, Sassari University, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Traccis
authors.forename: G
authors.initials: G
authors.lastname: Rosati
authors.forename: M F
authors.initials: MF
authors.lastname: Monaco
authors.forename: I
authors.initials: I
authors.lastname: Aiello
authors.forename: V
authors.initials: V
authors.lastname: Agnetti
mesh_terms: D000293:Adolescent; D000328:Adult; D005139:Eyeglasses; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use*; D008297:Male; D009103:Multiple Sclerosis / Q000503:physiopathology*; D009759:Nystagmus, Pathologic / Q000188:drug therapy*
chemical_list: D007538:Isoniazid