Successful treatment of acquired pendular elliptical nystagmus in multiple sclerosis with isoniazid and base-out prisms.
We treated 3 multiple sclerosis patients who had pendular nystagmus with isoniazid (800 to 1,000 mg/d). Isoniazid abolished the nystagmus and relieved oscillopsia in 2 patients but was ineffective in the 3rd in whom the nystagmus was damped with convergence and vision improved with converging (base-out) prisms.
Traccis
S
S
Neurological Clinic, Sassari University, Italy.
Rosati
G
G
Monaco
M F
MF
Aiello
I
I
Agnetti
V
V
D000293:Adolescent; D000328:Adult; D005139:Eyeglasses; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use*; D008297:Male; D009103:Multiple Sclerosis / Q000503:physiopathology*; D009759:Nystagmus, Pathologic / Q000188:drug therapy*
D007538:Isoniazid