[Experiences and clinical results following 99 kidney transplantations with kidneys from relatives].
99 living related kidney transplantations were performed between January 1967 and December 1988. At the time of observation 4 of 94 organ donors had died; there was no correlation between unilateral nephrectomy and the patient's death. Intraoperative (2.9%) and postoperative (25%) complications did not result in severe physical consequences for the organ donors. Hypertension was found in 2 donors. There was no decrease in function of the remaining kidneys. The 3-year organ survival of the transplanted kidney was 60% with "conventional immunosuppression" and 93% with cyclosporin. No association was found between HLA DR-matching and graft survival. Rejection episodes occurred significantly more often in the HLA DR-mismatched grafts.
Längle
F
F
I. Chirurgische Universitätsklinik, Wien.
Gnant
M
M
Sautner
T
T
Mühlbacher
F
F
Kretschmer
G
G
Traindl
O
O
Kovarik
J
J
Derfler
K
K
Balcke
P
P
Steger
J
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection / Q000235:genetics* / Q000276:immunology; D006680:HLA Antigens / Q000235:genetics; D006684:HLA-DR Antigens / Q000235:genetics; D006648:Histocompatibility / Q000235:genetics*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery*; D007677:Kidney Function Tests; D016030:Kidney Transplantation / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology*; D012307:Risk Factors; D014019:Tissue Donors
D006680:HLA Antigens; D006684:HLA-DR Antigens
Erfahrungen und klinische Ergebnisse nach 99 Verwandtennierentransplantationen.