title: Cyromazine pour-on for the prevention of cutaneous myiasis of sheep.
abstract: The results of trials on eight farms to assess the efficacy of two pour-on formulations containing cyromazine for the prevention of cutaneous myiasis of sheep are presented; data from trials on sheep with larval implants and on sheep kept in cages with adult flies are also reported. The incidence of cutaneous myiasis was reduced by between 87 per cent and 100 per cent for eight weeks when a formulation containing 6 per cent w/v cyromazine was used at an application rate of 60 to 85 mg of active ingredient/kg bodyweight. When a formulation containing 10 per cent w/v was used at an application rate of 50 to 100 mg/kg, the incidence of the condition was reduced by between 90 per cent and 100 per cent for eight weeks. Studies of sheep with larval implants, using the formulation containing 10 per cent w/v cyromazine at 50, 100 and 150 mg/kg bodyweight gave variable results with some animals at each dose rate having lost protection by the seventh week. When sheep were treated with the formulation containing 10 per cent w/v cyromazine at 50 or 100 mg/kg and exposed to adult flies in fly-proof cages they were completely protected for nine and eight weeks, respectively.
authors.affiliation: Ciba-Geigy Agrochemicals, Whittlesford, Cambridge.
authors.forename: B
authors.initials: B
authors.lastname: Lonsdale
authors.forename: D W
authors.initials: DW
authors.lastname: Tarry
authors.forename: F L
authors.initials: FL
authors.lastname: Bowen
authors.forename: D G
authors.initials: DG
authors.lastname: Stansfield
mesh_terms: D000287:Administration, Topical; D000818:Animals; D007814:Larva / Q000502:physiology; D009198:Myiasis / Q000517:prevention & control*; D012756:Sheep; D012757:Sheep Diseases / Q000517:prevention & control*; D012876:Skin Diseases, Parasitic / Q000517:prevention & control / Q000662:veterinary*; D014227:Triazines / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D014227:Triazines; C028704:cyromazine