title: Suspected familial renal disease in chow chows.
abstract: Renal disease was diagnosed in 6 young Chow Chows. Clinical abnormalities included vomiting, polyuria, polydipsia, and weight loss. Common abnormal laboratory findings were azotemia, hyperphosphatemia, hypocalcemia, nonregenerative anemia, and low urine specific gravity. All 6 dogs had similar microscopic renal lesions. characterized by interstitial fibrosis, a population of small glomeruli, and lack of inflammatory cells. A familial basis for the renal disease is suggested because of its development in 4 closely related dogs.
authors.affiliation: Department of Veterinary Pathology, College of Veterinary Medicine, University of Georgia, Athens 30602.
authors.forename: C A
authors.initials: CA
authors.lastname: Brown
authors.forename: W A
authors.initials: WA
authors.lastname: Crowell
authors.forename: S A
authors.initials: SA
authors.lastname: Brown
authors.forename: J A
authors.initials: JA
authors.lastname: Barsanti
authors.forename: D R
authors.initials: DR
authors.lastname: Finco
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D005260:Female; D007668:Kidney / Q000473:pathology; D007674:Kidney Diseases / Q000235:genetics / Q000662:veterinary*; D007676:Kidney Failure, Chronic / Q000235:genetics / Q000662:veterinary*; D008297:Male; D010375:Pedigree