Human immunodeficiency virus wasting syndrome may represent a treatable myopathy.
We evaluated 5 patients with the diagnosis of HIV wasting syndrome. None had severe diarrhea or other causes for malabsorption. All had myopathy by clinical, laboratory, and muscle biopsy criteria. Withdrawal of azidothymidine in 3 patients did not lead to improvement. Corticosteroid therapy was effective in 3 patients.
Simpson
D M
DM
Department of Neurology, Mount Sinai Medical Center, New York, NY.
Bender
A N
AN
Farraye
J
J
Mendelson
S G
SG
Wolfe
D E
DE
D000163:Acquired Immunodeficiency Syndrome / Q000503:physiopathology; D000328:Adult; D015658:HIV Infections / Q000503:physiopathology*; D006679:HIV Seropositivity / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D009135:Muscular Diseases / Q000188:drug therapy* / Q000503:physiopathology; D011241:Prednisone / Q000008:administration & dosage; D013997:Time Factors; D015431:Weight Loss; D015215:Zidovudine / Q000008:administration & dosage
D015215:Zidovudine; D011241:Prednisone