title: Influence of "nuclear" estrogen receptor content on prognosis of early stage carcinoma of the uterine body. A short-time follow-up.
abstract: Sixty-five patients with Stage I and II endometrial carcinoma were investigated. After a short-time follow-up (17-24 months) significant differences in frequency of relapses were observed between patients with tumors containing low amounts of estrogen receptor (ER less than 60 fmol/mg DNA) in the nuclear pellet, and those with tumors containing greater than 60 fmol ER/mg DNA (p = 0.01). Other prognostic factors showed no differences in frequency of relapses. In this small patient material with a short-time follow-up we therefore suggest that ER in the nuclear pellet may be an important prognostic factor.
authors.affiliation: Gynecologic Section, University Hospital, Lund, Sweden.
authors.forename: G
authors.initials: G
authors.lastname: Horvath
authors.forename: J E
authors.initials: JE
authors.lastname: Johnsson
authors.forename: C
authors.initials: C
authors.lastname: Tropé
authors.forename: L
authors.initials: L
authors.lastname: Samuelsson
authors.forename: P
authors.initials: P
authors.lastname: Alm
authors.forename: H
authors.initials: H
authors.lastname: Olsson
mesh_terms: D000230:Adenocarcinoma / Q000032:analysis* / Q000401:mortality; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D011960:Receptors, Estrogen / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis; D015996:Survival Rate; D014594:Uterine Neoplasms / Q000032:analysis* / Q000401:mortality
chemical_list: D011960:Receptors, Estrogen; D011980:Receptors, Progesterone