title: Esophageal carcinoma in Indian Jews of southern Israel. An epidemiologic study.
abstract: The incidence of esophageal cancer varies in different populations and localities. The varied composition of the immigrant population of southern Israel afforded us an opportunity to investigate the frequency of the disease. The results of a retrospective study (1961-1985) revealed a high mean age-adjusted incidence rate (per 10(5)) in immigrant Indian men (6.5 +/- 2.17) and Indian women (17.2 +/- 5.12). Rates in all non-Indian immigrants were significantly lower: men 2.7 +/- 1.19, women 2.1 +/- 0.24. The relative risk of developing the disease was significantly higher in Indians. The age at diagnosis was lower in Indian women (54.6 +/- 10.4 years) than Indian men and other immigrants (p less than 0.05). The clinical features were similar in all cases. The risk factors in Indian men were not apparent; in women, the indiscrete use of spices might have raised the rate of esophageal cancer. The disease is more frequent in Indian populations in several parts of the world, and vigilance is required on the part of physicians.
authors.affiliation: Department of Internal Medicine, Soroka Medical Center, Beer Sheva, Israel.
authors.forename: H S
authors.initials: HS
authors.lastname: Odes
authors.forename: J
authors.initials: J
authors.lastname: Gross
authors.forename: T
authors.initials: T
authors.lastname: Lozover
authors.forename: H
authors.initials: H
authors.lastname: Vardi
authors.forename: J
authors.initials: J
authors.lastname: Krawiec
mesh_terms: D000328:Adult; D003212:Condiments; D003680:Deglutition Disorders / Q000209:etiology; D004938:Esophageal Neoplasms / Q000150:complications / Q000453:epidemiology*; D005247:Feeding Behavior / Q000208:ethnology; D005260:Female; D006801:Humans; D015994:Incidence; D007194:India / Q000208:ethnology; D007557:Israel / Q000453:epidemiology; D007585:Jews; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors