Neuroradiologic findings in leptomeningeal carcinomatosis: the value interest of gadolinium-enhanced MRI.
Four patients with leptomeningeal metastases documented by neuroradiological examinations are reported. All had central nervous system or systemic neoplasms and showed clinical signs of carcinomatous meningitis. Gadolinium-enhanced MRI (Gd-MRI) disclosed for each patient pathological foci, allowing delineation of the extent of meningeal disease. Although non-specific, these findings, combined with the clinical context and CSF analysis, may lead to a rapid diagnosis and treatment of carcinomatous meningitis, even when malignant cells are not detected in the cerebrospinal fluid.
Rodesch
G
G
Department of Neuroradiology, Hôpital Erasme, Université Libre de Bruxelles, Belgium.
Van Bogaert
P
P
Mavroudakis
N
N
Parizel
P M
PM
Martin
J J
JJ
Segebarth
C
C
Van Vyve
M
M
Baleriaux
D
D
Hildebrand
J
J
D000328:Adult; D000368:Aged; D001932:Brain Neoplasms; D002648:Child; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D008175:Lung Neoplasms; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000556:secondary*; D008579:Meningioma / Q000175:diagnosis / Q000556:secondary*; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid
D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA