title: Patient variables and the subarachnoid spread of hyperbaric bupivacaine in the term parturient.
abstract: To determine if age, height, weight, body mass index, or vertebral column length significantly influence the distribution of sensory analgesia or anesthesia after subarachnoid injection of hyperbaric bupivacaine, 52 women presenting for cesarean section were studied. All received 15 mg hyperbaric bupivacaine via subarachnoid injection at L-2 or L-3. Fifteen minutes after injection, while the women lay supine on a horizontal operating table, the maximum cephalad extent of sensory analgesia (loss of sensation of sharpness to pin prick) and anesthesia (loss of sensation of light touch) was determined. Age (20-42 yr), height (146.9-174.0 cm), weight (55.5-136.4 kg), body mass index (19.2-50.0 kg/m2), and vertebral column length (49.6-67.0 cm) did not correlate with the spread of sensory blockade. In conclusion, in parturients of age, height, weight, body mass index, and vertebral column length within the aforementioned ranges, it is not necessary to vary the dose of injected hyperbaric bupivacaine with changes in any of the patient variables studied.
authors.affiliation: Department of Anesthesiology, Thomas Jefferson University, Philadelphia, Pennsylvania.
authors.forename: M C
authors.initials: MC
authors.lastname: Norris
mesh_terms: D000328:Adult; D000367:Age Factors; D000773:Anesthesia, Obstetrical; D000775:Anesthesia, Spinal; D001827:Body Height; D015992:Body Mass Index; D001835:Body Weight; D002045:Bupivacaine / Q000008:administration & dosage* / Q000493:pharmacokinetics; D002585:Cesarean Section; D005260:Female; D005947:Glucose; D006801:Humans; D011247:Pregnancy; D012996:Solutions; D013046:Specific Gravity; D013131:Spine / Q000033:anatomy & histology; D013346:Subarachnoid Space
chemical_list: D012996:Solutions; D005947:Glucose; D002045:Bupivacaine