title: [Usefulness of midazolam for premedication before local anesthesia].
abstract: The optimal dose and adverse effects of midazolam for premedication were evaluated in 45 patients undergoing local anesthesia. The patients were divided into 3 groups and administered midazolam intramuscularly: group-A 0.075 mg.kg-1, group-B 0.1mg.kg-1, group-C 0.125 mg.kg-1. In this study, concerning sedative and hypnotic effects, the administration of midazolam (0.075-0.1mg.kg-1) showed satisfactory results except in conduction anesthesia of upper extremities (brachial plexus block). However, severe decrease in PaO2 was observed in relatively younger patients. Therefore, it is necessary to observe patients carefully during perioperative period.
authors.affiliation: Department of Anesthesiology, Osaka Medical College, Takatsuki.
authors.forename: M
authors.initials: M
authors.lastname: Akatsuka
authors.forename: H
authors.initials: H
authors.lastname: Sasaki
authors.forename: H
authors.initials: H
authors.lastname: Kataoka
authors.forename: M
authors.initials: M
authors.lastname: Hyodo
authors.forename: F
authors.initials: F
authors.lastname: Ohno
authors.forename: H
authors.initials: H
authors.lastname: Umegaki
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000772:Anesthesia, Local; D006801:Humans; D007273:Injections, Intramuscular; D008874:Midazolam / Q000008:administration & dosage* / Q000009:adverse effects; D008875:Middle Aged; D011229:Preanesthetic Medication / Q000009:adverse effects
chemical_list: D008874:Midazolam