Influence of local anesthetic solution on postdural puncture headache.
A total of 2,511 patients who received spinal anesthesia for cesarean delivery were observed for the development of postdural puncture headache (PDPH); 804 patients received a mixture of tetracaine and procaine, 942 received bupivacaine-glucose, and 765 received lidocaine-glucose. They were observed for the development of PDPH for a minimum of 72 h. PDPH occurred in 9.54% of patients who received lidocaine-glucose during the first 36 h compared with 7.64% of patients who received bupivacaine-glucose and 5.85% of patients who received tetracaine-procaine. The differences between all groups was statistically significant. No differences were found in the percentage of patients who ultimately required epidural blood patch for relief of symptoms after 36 h.
Naulty
J S
JS
Department of Anesthesia, George Washington University, Washington, DC.
Hertwig
L
L
Hunt
C O
CO
Datta
S
S
Ostheimer
G W
GW
Weiss
J B
JB
D000328:Adult; D000773:Anesthesia, Obstetrical; D000775:Anesthesia, Spinal; D000779:Anesthetics, Local; D001769:Blood; D002045:Bupivacaine; D002585:Cesarean Section; D005260:Female; D005947:Glucose; D006261:Headache / Q000209:etiology*; D006801:Humans; D007268:Injections, Epidural; D008012:Lidocaine; D011247:Pregnancy; D012996:Solutions; D013129:Spinal Puncture / Q000009:adverse effects*; D013748:Tetracaine
D000779:Anesthetics, Local; D012996:Solutions; D013748:Tetracaine; D008012:Lidocaine; D005947:Glucose; D002045:Bupivacaine