title: Gastric emptying for solids in patients with duodenal ulcer before and after highly selective vagotomy.
abstract: In a series of 31 duodenal ulcer patients (23 males and 8 females), who underwent a highly selective vagotomy, gastric emptying characteristics of a solid meal, labeled with [99mTc]stannous colloid, were assessed before, two weeks and six months after operation. The clinical diagnosis was confirmed by endoscopy and x-ray; failure of treatment with H2 antagonists or antacids during 1-18 (mean 5) years was the direct indication for operative treatment. A temporary delay in gastric emptying is noted two weeks after operation (T1/2: 124 vs 57 min). After six months, gastric emptying time has practically normalized. It appears that this is the result of the preservation of the antropyloric vagal nerve supply. In these patients, a 10% recurrence rate is noted, comparable to the results in the literature. Highly selective vagotomy proves to be a safe and effective procedure with few side effects. It does not impair gastric motility.
authors.affiliation: Department of Surgical Research University of Antwerp, Belgium.
authors.forename: W
authors.initials: W
authors.lastname: Mistiaen
authors.forename: R
authors.initials: R
authors.lastname: Van Hee
authors.forename: P
authors.initials: P
authors.lastname: Blockx
authors.forename: A
authors.initials: A
authors.lastname: Hubens
mesh_terms: D000328:Adult; D003102:Colloids; D004381:Duodenal Ulcer / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005746:Gastric Emptying / Q000502:physiology*; D006801:Humans; D008297:Male; D011184:Postoperative Period; D013667:Technetium; D017556:Technetium Compounds; D013997:Time Factors; D014001:Tin; D017971:Tin Compounds; D014629:Vagotomy, Proximal Gastric
chemical_list: D003102:Colloids; D017556:Technetium Compounds; D017971:Tin Compounds; C033493:technetium Tc 99m tin colloid; D013667:Technetium; D014001:Tin