title: [Suppression by luteectomy of the simultaneous increase in intramammary pressure and blood oxytocin levels induced by the injection of PGF2-alpha in ewes].
abstract: Seven lactating Lacaune ewes underwent either a total luteectomy on day 19 of pregnancy (D19) (compensated from that stage by a daily progesterone supplementation of 25 mg to ensure embryonic survival; group 1:4 animals) or a control laparotomy (group 2: 3 animals). Intra-jugular injection of 200 micrograms of a synthetic PGF2 alpha analogue (Dinolytic, Upjohn) caused an increase in the intramammary pressure (IMP) and a concomitant rise in oxytocinaemia only in the presence of a corpus luteum, ie in all ewes of groups 1 and 2 before D19 and only in those of group 2 after that stage. These experiments confirm that the corpus luteum, and not the other ovarian compartments, releases oxytocin when prostaglandin F2 alpha is administered.
authors.affiliation: Laboratoire de la traite, INRA, Rennes, France.
authors.forename: J
authors.initials: J
authors.lastname: Labussière
authors.forename: M C
authors.initials: MC
authors.lastname: Lacroix
authors.forename: J F
authors.initials: JF
authors.lastname: Combaud
authors.forename: F A
authors.initials: FA
authors.lastname: de la Chevalerie
authors.forename: P
authors.initials: P
authors.lastname: Thomas
mesh_terms: D000818:Animals; D003338:Corpus Luteum / Q000187:drug effects / Q000502:physiology* / Q000601:surgery; D015237:Dinoprost / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D007275:Injections, Intravenous; D007601:Jugular Veins; D008321:Mammary Glands, Animal / Q000187:drug effects / Q000502:physiology*; D010121:Oxytocin / Q000097:blood* / Q000378:metabolism; D011247:Pregnancy; D011312:Pressure; D011374:Progesterone / Q000097:blood; D012636:Secretory Rate / Q000187:drug effects; D012756:Sheep / Q000502:physiology
chemical_list: D011374:Progesterone; D010121:Oxytocin; D015237:Dinoprost
vernacular_title: Suppression par la lutectomie de l'accroissement simultané de la pression intramammaire et de l'ocytocinémie, induit par l'injection de PGF2 alpha chez la brebis.