Adenocarcinoma of the stomach following radical radiotherapy for testicular cancer.
Two male patients who underwent curative surgery and adjuvant radiotherapy (with further chemotherapy in one) for testicular cancer developed adenocarcinoma of the stomach 5 and 19 years after treatment. The stomach is included in the field of radiotherapy used to treat the para-aortic lymph nodes and this may lead to dysplastic changes in the stomach mucosa which can lead to frank malignancy. Early endoscopy should be offered to patients with dyspeptic symptoms after adjuvant radiotherapy for testicular cancer.
Griffith
C D
CD
Department of Surgery, Queen's Medical Centre, Nottingham, UK.
Chadderton
R
R
Bourke
J B
JB
D000230:Adenocarcinoma / Q000209:etiology* / Q000473:pathology; D000328:Adult; D003131:Combined Modality Therapy; D004407:Dysgerminoma / Q000532:radiotherapy / Q000628:therapy; D006801:Humans; D015182:Lymphatic Irradiation / Q000009:adverse effects; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D011878:Radiotherapy / Q000009:adverse effects*; D011879:Radiotherapy Dosage; D013274:Stomach Neoplasms / Q000209:etiology* / Q000473:pathology; D013724:Teratoma / Q000532:radiotherapy / Q000628:therapy; D013736:Testicular Neoplasms / Q000532:radiotherapy* / Q000628:therapy