[Plasmocellular leukemia with IgD paraproteinemia].
The authors describe the case of an 80-year-old woman with a plasmocytoma IgD-lambda, which developed into plasmocellular leukaemia. The laboratory finding reminded at first of chronic lymphatic leukaemia. The correct diagnosis was assisted by marked leucocytosis with the release of a major number of plasmatic cells into the peripheral blood stream. The finding was confirmed on the basis of sternal puncture, cytochemical examination, immunochemical examination of the blood and urine and X-ray of the skull. Treatment led to marked clinical and laboratory improvement. The patient died, however, from pneumonia three months after establishment of the diagnosis. Post-mortem examination revealed an extensive infiltration of many organs and a myelomatous kidney. The authors present some differential diagnostic reflections on plasmocellular leukaemia.
Matĕja
F
F
Oddĕlení klinické hematologie fakultní nemocnice Brno.
Tichý
M
M
Novotný
J
J
Foukal
T
T
D000368:Aged; D005260:Female; D006801:Humans; D007072:Immunoglobulin D; D007952:Leukemia, Plasma Cell / Q000150:complications* / Q000175:diagnosis; D010265:Paraproteinemias / Q000150:complications* / Q000175:diagnosis
D007072:Immunoglobulin D
Plasmocelulární leukémie s paraproteinémií IgD.