title: [The importance of a sequence of laboratory diagnostic micromethods in detecting tumors in subjects with complaints of functional disorders of the gastrointestinal tract].
abstract: The paper is concerned with the diagnostic value of a complex of laboratory micromethods for detection of tumors which were used in 421 subjects who had been endoscopically examined for gastrointestinal discomfort. The methods assured correct diagnosis in 61.1% and gave false-positive results in 35.6%. Ninety-seven percent of the latter group showed preneoplastic lesions of the stomach which must be followed up. Half of the patients with preneoplastic lesions of the stomach revealed changes in the physico-chemical properties of blood similar to those observed in gastric cancer patients. False-negative results were obtained in 3.8% of the whole group (far-advanced cancer). The sensitivity of the suggested complex of micromethods for gastric cancer detection was 86%, reliability--61 and specificity--52%.
authors.forename: N A
authors.initials: NA
authors.lastname: Grigorovich
authors.forename: G Iu
authors.initials: GIu
authors.lastname: Bychkova
authors.forename: P L
authors.initials: PL
authors.lastname: Monastyrnaia
mesh_terms: D014408:Biomarkers, Tumor / Q000097:blood*; D019411:Clinical Laboratory Techniques / Q000379:methods; D004064:Digestive System / Q000503:physiopathology*; D005340:Fibrinogen / Q000032:analysis; D005453:Fluorescence; D005770:Gastrointestinal Neoplasms / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D009088:Mucoproteins / Q000097:blood
chemical_list: D014408:Biomarkers, Tumor; D009088:Mucoproteins; D005340:Fibrinogen
vernacular_title: Znachenie kompleksa mikrometodov laboratornoĭ diagnostiki v vyiavlenii opukholeĭ u lits s zhalobami na narushenie funktsiĭ zheludochno-kishechnogo trakta.