A case of sclerosing lymphangitis of the lip.
A 62-year-old woman noted a cord-like swelling on the inner surface of her upper lip. A cross-section of the lesion showed a radial-shaped lumen surrounded by a thickened fibrous wall. Immunohistochemical staining with the anti-factor VIII-related antigen (FVIII-RAg) antibody was negative on the luminal surface and swollen wall, although the vasa vasorum in the swollen wall were positive. The lesion was thus considered to be of lymphatic origin; that is, it derived from a lymphatic collecting vessel. For the present case, the term 'lymphangiopathia obliterans' is considered appropriate. This is the second report of such a lesion appearing on the lip in the literature.
Inamura
K
K
Department of Dermatology, Kitasato University School of Medicine, Kanagawa, Japan.
Suzuki
Y
Y
Nishioka
K
K
Nishiyama
S
S
D000941:Antigens / Q000032:analysis; D005260:Female; D006801:Humans; D008046:Lip; D008205:Lymphangitis / Q000276:immunology / Q000473:pathology*; D008875:Middle Aged; D012598:Sclerosis; D014841:von Willebrand Factor / Q000032:analysis
D000941:Antigens; C029417:Von Willebrand antigen; D014841:von Willebrand Factor