Translocation t(11;13) and deletion of chromosome 7 in a patient with acute myelomonocytic leukemia.
A translocation between chromosomes 11 and 13, together with a deletion of the long arm of chromosome 7, was found in the bone marrow of a patient with acute myelomonocytic leukemia (AMMOL). All three breakpoints are believed to be associated with a predisposition to malignancy.
Pati
A
A
Department of Haematology, Coventry and Warwickshire Hospital, England.
Creasy
M
M
Challinor
P R
PR
Ng
J P
JP
Harris
R I
RI
D000368:Aged; D002871:Chromosome Banding; D002872:Chromosome Deletion; D002880:Chromosomes, Human, Pair 11; D002882:Chromosomes, Human, Pair 13; D002897:Chromosomes, Human, Pair 7; D006801:Humans; D007621:Karyotyping; D015479:Leukemia, Myelomonocytic, Acute / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic