Exacerbation of psoriasis precipitated by an oestradiol-testosterone implant.
A 47-year-old woman developed widespread psoriasis following insertion of a combined oestradiol-testosterone implant into her anterior abdominal wall for post-oophorectomy symptoms. The rash did not resolve until the effects of the implant had worn off and recurred following insertion of a second oestradiol-testosterone implant. Implants containing oestradiol alone were tolerated. We have found no previous reports suggesting a relationship between testosterone implants and psoriasis.
O'Driscoll
J B
JB
Skin Hospital, Salford, UK.
August
P J
PJ
D004343:Drug Implants; D004958:Estradiol / Q000009:adverse effects; D005260:Female; D006801:Humans; D008875:Middle Aged; D011565:Psoriasis / Q000139:chemically induced*; D013739:Testosterone / Q000009:adverse effects*
D004343:Drug Implants; D013739:Testosterone; D004958:Estradiol