title: Endoscopic localization of the squamocolumnar junction before cervical cone biopsy in 284 patients.
abstract: A preoperative examination of the endocervical canal was performed in 284 patients scheduled for excisional cone biopsy because of abnormal cervical cytology and unsatisfactory colposcopy. The information obtained regarding the depth of the new squamocolumnar junction (SCJ) was used to tailor the length of the cone specimen in an attempt to remove the entire transformation zone (TZ), and was associated with a low rate of incomplete disease excision. An analysis of the data generated by this study indicates that the position of the new SCJ is influenced by age, menopausal status, and the use of estrogen-containing medication.
authors.affiliation: University Department of Obstetrics and Gynaecology, Northern General Hospital, Sheffield, England.
authors.forename: N
authors.initials: N
authors.lastname: Saunders
authors.forename: D
authors.initials: D
authors.lastname: Anderson
authors.forename: E
authors.initials: E
authors.lastname: Sheridan
authors.forename: L
authors.initials: L
authors.lastname: Gilbert
authors.forename: F
authors.initials: F
authors.lastname: Sharp
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001706:Biopsy / Q000295:instrumentation*; D002278:Carcinoma in Situ / Q000473:pathology*; D002584:Cervix Uteri / Q000473:pathology*; D020681:Colposcopes; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D002583:Uterine Cervical Neoplasms / Q000473:pathology*