Folate treatment of a boy with fragile-X syndrome.
A severely behaviourally disturbed three year old boy with the fragile-X syndrome was treated with intermittent folate therapy over a period of 2 years. No behavioural improvement was noted in this time but variations between cultural regimes for the successful detection of the fragile-X marker were observed.
Webb
T
T
University of Birmingham, Department of Clinical Genetics, Birmingham Maternity Hospital, Edgbaston, England.
Crawley
P
P
Bundey
S
S
D002675:Child, Preschool; D005492:Folic Acid / Q000008:administration & dosage*; D005600:Fragile X Syndrome / Q000188:drug therapy* / Q000235:genetics / Q000523:psychology; D006801:Humans; D007621:Karyotyping; D008297:Male; D010375:Pedigree; D012729:Sex Chromosome Aberrations / Q000188:drug therapy*; D014960:X Chromosome / Q000187:drug effects
D005492:Folic Acid