title: The effect of plasma volume expansion on uteroplacental blood flow in hypertensive pregnancies.
abstract: The effect of plasma volume expansion on uteroplacental blood flow was investigated in 20 hypertensive women in the 3rd trimester of pregnancy by measuring the radioactivity in the region of the placenta with a gamma camera after an intravenous injection of indium-113. Despite a significant increase in plasma volume there was no change in maternal blood pressure or in uteroplacental blood flow. This suggests an autoregulation of both blood pressure and uteroplacental blood flow.
authors.affiliation: Department of Obstetrics and Gynaecology, University of Cape Town.
authors.forename: A E
authors.initials: AE
authors.lastname: Rees
authors.forename: D A
authors.initials: DA
authors.lastname: Davey
authors.forename: J
authors.initials: J
authors.lastname: Boniaszczuk
authors.forename: J
authors.initials: J
authors.lastname: Smith
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D005260:Female; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D010920:Placenta / Q000098:blood supply*; D010952:Plasma Substitutes / Q000494:pharmacology*; D010953:Plasma Volume / Q000502:physiology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000503:physiopathology*; D011263:Pregnancy Trimester, Third
chemical_list: D010952:Plasma Substitutes