title: Maintenance of polygenic variation through mutation-selection balance: bifurcation analysis of a biallelic model.
abstract: Biallelic models which ignore linkage disequilibrium have been used to study variability maintained by mutation in the presence of Gaussian stabilizing selection. Recent work of Barton (1986) showed that these models have stable equilibria at which the mean phenotype differed from the optimum, and that the variability maintained at such equilibria would be higher than at the symmetric equilibria calculated by Bulmer (1980) and others. Here I determine the bifurcation structure of this model, and confirm and extend Barton's results. The form of the bifurcations gives information about the domains of attraction of various equilibria, and shows why the nonsymmetric equilibria may not be observed. The techniques may prove useful in the analysis of other population genetic models.
authors.affiliation: Division of Environmental Studies, University of California, Davis 95616.
authors.forename: A
authors.initials: A
authors.lastname: Hastings
mesh_terms: D000483:Alleles; D005796:Genes; D014644:Genetic Variation; D008433:Mathematics; D008957:Models, Genetic; D009154:Mutation; D012641:Selection, Genetic