title: [A case-control study of the etiologic factors of a multiple primary cancer following a prior first breast cancer].
abstract: At the Kanagawa Cancer Center, the cases of 48 women who were found to have a multiple primary cancer (MPC) and who had previously had a first breast cancer (FBC) were reviewed, and a hospital-based, matched-pair, case-control study was performed. Studied were the effects of the reproductive factors, the therapies for their FBC, their drinking and smoking habits, and similar criteria on the development of the MPC. The case-control pairs were matched for age, year of their FBC diagnosis, and place of residence. The controls had only breast cancer and each lived beyond the MPC patient with whom they had been matched. The odds ratios for radiation therapy and drinking habits, calculated by McNemar's Test, were 4.00 (95% CI = 1.06-17.82) and 8.00 (1.03-170.60), respectively.
authors.affiliation: Dept. of Epidemiology, Kanagawa Cancer Center.
authors.forename: N
authors.initials: N
authors.lastname: Okamoto
authors.forename: S
authors.initials: S
authors.lastname: Morio
authors.forename: S
authors.initials: S
authors.lastname: Kawahara
authors.forename: A
authors.initials: A
authors.lastname: Yoshida
authors.forename: T
authors.initials: T
authors.lastname: Suzuki
mesh_terms: D000328:Adult; D000368:Aged; D000428:Alcohol Drinking; D001943:Breast Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000532:radiotherapy; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology / Q000209:etiology*; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology / Q000209:etiology; D012907:Smoking