[Hereditary protein C deficiency and portal vein thrombosis].
Inherited defects of the natural coagulation inhibitors predispose patients to thrombosis. These disorders have similar clinical presentations with a strong family of thrombosis, episodes of recurrent venous thromboembolism, beginning in early adulthood. We report a case of upper gastrointestinal bleeding in a patient with portal hypertension due to portal-vein thrombosis secondary to hereditary protein C deficiency, an association that has seldom been reported. We conclude that protein C deficiency should be investigated in thrombotic states, namely after more frequent causes have been excluded.
dos Santos
J N
JN
Serviço de Medicina 4, Hospital de Santa Maria, Faculdade de Medicina de Lisboa.
Mello e Silva
A
A
Alexandrino
P
P
Saldanha
T
T
Carreira
M O
MO
Ferreira
E
E
de Pádua
F
F
D005190:Family; D006801:Humans; D008297:Male; D008875:Middle Aged; D011169:Portal Vein; D020151:Protein C Deficiency; D012008:Recurrence; D013927:Thrombosis / Q000209:etiology* / Q000235:genetics
Deficiência hereditária de proteína C e trombose da veia porta.