[Endothelial changes in the pulmonary blood vessels of mice with Lewis lung carcinoma and experimental stress].
The influence of surgical tumour removal and of the emotional-pain stress described by Desiderato on the lung metastases development and lung vascular internal surface state was studied in C57BL mice with Lewis carcinoma. Scanning electron microscopy revealed a stress-damaging effect on vascular walls. It is possible to assume that the stress damage of pulmonary blood vessels greatly influences the stimulation of metastases. Concrete mechanisms responsible for this phenomenon are elucidated.
Nadiradze
Z O
ZO
Shmal'ko
Iu P
IuP
Balitskiĭ
K P
KP
Pinchuk
V G
VG
D000818:Animals; D002196:Capillaries / Q000648:ultrastructure; D004730:Endothelium, Vascular / Q000648:ultrastructure*; D008168:Lung / Q000098:blood supply* / Q000648:ultrastructure; D008175:Lung Neoplasms / Q000601:surgery / Q000648:ultrastructure*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008855:Microscopy, Electron, Scanning; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D013315:Stress, Psychological / Q000473:pathology* / Q000601:surgery; D013997:Time Factors
Izmeneniia éndoteliia krovenosnykh sosudov legkogo mysheĭ s kartsinomoĭ legkogo L'iuis pri éksperimental'nom stresse.