[Characteristics of chromosomal and mitotic disorders in patients with acute non-lymphoblastic leukemia exposed to chemical factors].
Cytogenetic and mitotic disorders were studied in 151 patients with acute non-lymphoblastic leukemia. A significant rise in the incidence of clonal disorders with predominant affection of chromosomes 5 and 7, and an increase in the percentage of cases with the presence of pathologic mitoses in hemopoietic cells have been recorded in patients who, due to their occupation, have been exposed to potentially mutagenic chemical substances.
Zedginidze
A G
AG
Chakvetadze
L V
LV
Abdushelishvili
R G
RG
Chinchaladze
Ts V
TsV
Dzhanashiia
M D
MD
Glonti
L M
LM
D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D002617:Chemical Industry; D002869:Chromosome Aberrations / Q000235:genetics*; D002895:Chromosomes, Human, Pair 5 / Q000187:drug effects*; D002897:Chromosomes, Human, Pair 7 / Q000187:drug effects*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000139:chemically induced / Q000235:genetics*; D008938:Mitosis / Q000187:drug effects*; D009784:Occupational Diseases / Q000139:chemically induced / Q000235:genetics*; D014586:USSR
D000395:Air Pollutants, Occupational
Kharakter khromosomnykh i mitoticheskikh narusheniĭ u bol'nykh ostrymi nelimfoblastnymi leĭkozami, podvergavshikhsia vozdeĭstviiu khimicheskikh faktorov.