title: [Soluble interleukin 2 receptor (sIL-2R) in chronic polyarthritis].
abstract: An ELISA was used to measure soluble interleukin-2 receptor (sIL-2R) in the sera and synovial fluid (SF) of patients with rheumatoid arthritis (RA). Patients with seropositive, as well as seronegative RA had raised levels of sIL-2R in serum and SF compared to patients with osteoarthritis and sex-age matched healthy subjects. According to literature, sIL-2R levels in the sera of RA-patients may be a useful marker of disease activity. Increased sIL-2R levels in SF show new aspects in pathophysiology of RA.
authors.affiliation: Rheumatologische Universitätsklinik, Felix Platter-Spital, Basel, Schweiz.
authors.forename: C
authors.initials: C
authors.lastname: Herzog
authors.forename: A
authors.initials: A
authors.lastname: Herzog
authors.forename: A
authors.initials: A
authors.lastname: Aeschlimann
authors.forename: H
authors.initials: H
authors.lastname: Gerber
authors.forename: W
authors.initials: W
authors.lastname: Müller
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001172:Arthritis, Rheumatoid / Q000188:drug therapy / Q000276:immunology*; D003524:Cyclosporins / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D015375:Receptors, Interleukin-2 / Q000032:analysis*; D012217:Rheumatoid Factor / Q000032:analysis; D013582:Synovial Fluid / Q000276:immunology*
chemical_list: D003524:Cyclosporins; D015375:Receptors, Interleukin-2; D012217:Rheumatoid Factor
vernacular_title: Löslicher Interleukin-2-Rezeptor (sIL-2R) bei der chronischen Polyarthritis.