title: Studies on the interactions of two different serotypes of Actinobacillus pleuropneumoniae.
abstract: In vitro and in vivo interactions of various field strains of Actinobacillus pleuropneumoniae of serotypes 1, 2, 5 and 7 were studied. There was no influence of one serotype over the other when strains belonging to two serotypes were cultivated together in vitro. In vivo interactions showed predominance of serotype 1 over other serotypes when a strain of serotype 1 was inoculated together with a strain of serotype 2 or 5 in mice. Serotype 1 strain remained predominant irrespective of whether it was inoculated before or after the inoculation of serotype 2 strain. The mortality caused by the inoculation of two strains was higher than the mortality caused by a single strain. Early mortality was observed on inoculation of strains of serotype 2, 5 or 7 along with a strain of serotype 1. Both serotypes could be detected in the blood on cultural examination of mice infected with mixed serotypes.
authors.affiliation: Department of Pathology and Microbiology, Faculty of Veterinary Medicine, University of Montreal, Saint-hyacinthe, Quebec, Canada.
authors.forename: J P
authors.initials: JP
authors.lastname: Komal
authors.forename: K R
authors.initials: KR
authors.lastname: Mittal
mesh_terms: D000187:Actinobacillosis / Q000276:immunology; D000188:Actinobacillus / Q000145:classification / Q000276:immunology*; D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis; D008099:Liver / Q000276:immunology; D008168:Lung / Q000276:immunology; D008297:Male; D051379:Mice; D011001:Pleuropneumonia / Q000382:microbiology / Q000662:veterinary; D012703:Serotyping; D013154:Spleen / Q000276:immunology; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology
chemical_list: D000942:Antigens, Bacterial