Characteristic new members of the phthiocerol and phenolphthiocerol families from Mycobacterium ulcerans.
Diacyl phthiodiolone A and phenolphthiodiolone A lipids were isolated from two strains of Mycobacterium ulcerans. The diol units of the phthiodiolone A and phenolphthiodiolone A components were shown to have erythro stereochemistry by infrared spectroscopy and proton nuclear magnetic resonance of an acetal derivative. This stereochemistry is shared only by related diols from M. marinum, the diols from M. bovis, M. kansasii, M. leprae and M. tuberculosis having threo stereochemistry.
Besra
G S
GS
Department of Chemistry, University Newcastle-upon-Tyne, U.K.
Minnikin
D E
DE
Sharif
A
A
Stanford
J L
JL
D005233:Fatty Alcohols / Q000302:isolation & purification*; D006017:Glycolipids / Q000302:isolation & purification*; D008055:Lipids / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D009161:Mycobacterium / Q000032:analysis*; D013045:Species Specificity; D013237:Stereoisomerism
D005233:Fatty Alcohols; D006017:Glycolipids; D008055:Lipids