title: The effects of fractioned human urine on urease-induced crystallisation in vitro.
abstract: Previous studies have shown human urine to have an inhibitory action on urease-induced crystallisation. Centrifugation and 0.45 microns filtration of the urine did not reduce this activity. This eliminates larger urine particles as being the cause of the inhibitory activity. Both the retenate and the filtrate after ultrafiltration of urine with a 100.000 mol weight cut-off influenced the urease-induced crystallisation of magnesium ammonium phosphate and calcium phosphate. The results indicate that the inhibitory action is exerted by more than one urinary component.
authors.affiliation: Department of Urology, Sahlgrenska Hospital, University of Göteborg, Sweden.
authors.forename: H
authors.initials: H
authors.lastname: Hedelin
authors.forename: L
authors.initials: L
authors.lastname: Grenabo
authors.forename: S
authors.initials: S
authors.lastname: Petterson
mesh_terms: D002130:Calcium Phosphates; D003460:Crystallization; D006801:Humans; D066298:In Vitro Techniques; D008274:Magnesium; D017616:Magnesium Compounds; D008970:Molecular Weight; D010710:Phosphates; D000069877:Struvite; D014462:Ultrafiltration; D014510:Urease / Q000494:pharmacology*; D014556:Urine
chemical_list: D002130:Calcium Phosphates; D017616:Magnesium Compounds; D010710:Phosphates; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; C020243:calcium phosphate; D000069877:Struvite; D014510:Urease; D008274:Magnesium; C485829:calcium phosphate, dibasic, anhydrous