title: The ventricular-brain ratio (VBR) in functional psychoses: the relationship of lateral ventricular and total intracranial area.
abstract: CT scans were performed on 72 consecutive patients with a functional psychosis, and compared with 50 community controls. There was a specific difference in lateral ventricular area between these two groups but it accounted for only 11% of the variance in this measure. In contrast, racial and sexual differences in the ventricular-brain ratio (VBR) related to differences in intracranial area. It is argued that analysis of variance, using lateral ventricular area and intra-cranial area, is more informative than VBR in examining these structural changes in functional psychoses.
authors.affiliation: Department of Psychological Medicine, King's College Hospital, London.
authors.forename: I
authors.initials: I
authors.lastname: Harvey
authors.forename: M
authors.initials: M
authors.lastname: Williams
authors.forename: B K
authors.initials: BK
authors.lastname: Toone
authors.forename: S W
authors.initials: SW
authors.lastname: Lewis
authors.forename: S W
authors.initials: SW
authors.lastname: Turner
authors.forename: P
authors.initials: P
authors.lastname: McGuffin
mesh_terms: D000293:Adolescent; D000328:Adult; D001714:Bipolar Disorder / Q000473:pathology; D001921:Brain / Q000473:pathology*; D001925:Brain Damage, Chronic / Q000523:psychology*; D002552:Cerebral Ventricles / Q000473:pathology*; D003702:Delusions / Q000473:pathology; D003866:Depressive Disorder / Q000473:pathology; D003937:Diagnosis, Differential; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D006212:Hallucinations / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000473:pathology*; D011446:Prospective Studies; D011618:Psychotic Disorders / Q000473:pathology*; D012559:Schizophrenia / Q000473:pathology; D014057:Tomography, X-Ray Computed