[Antigen, common for mature human B- and T-lymphocytes, detected with the use of autolymphocytotoxins].
The investigation of adsorption capacity of B- and T-lymphocytes in respect to autolymphocytotoxic antibodies (ALCTA) has shown that these two populations of mature cells have a common antigen against which ALCTA are directed. This antigen is insufficiently expressed of pathologic cells of patients with B-cellular variant of chronic lymphoid leukemia (CLL). B-lymphocytes of patients with malignant non-Hodgkin's lymphoma, hairy-cell leukemia, Waldenström's macroglobulinemia are more mature, as compared to those of CLL patients, and carry surface antigens to which autoantibodies are directed.
Zotikov
E A
EA
Golovkina
L L
LL
Sevast'ianova
M G
MG
Kovaleva
L G
LG
Gabrilevskaia
O V
OV
D000937:Antigen-Antibody Reactions; D000961:Antilymphocyte Serum / Q000276:immunology*; D001323:Autoantibodies / Q000276:immunology*; D001402:B-Lymphocytes / Q000276:immunology*; D002478:Cells, Cultured; D006680:HLA Antigens / Q000032:analysis* / Q000276:immunology; D006801:Humans; D066298:In Vitro Techniques; D008232:Lymphoproliferative Disorders / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
D000961:Antilymphocyte Serum; D001323:Autoantibodies; D006680:HLA Antigens
Antigen, obshchiĭ dlia zrelykh B- i T-limfotsitov cheloveka, obnaruzhivaemyĭ s pomoshch'iu autolimfotsitotoksinov.