title: Intra-oral softening of bovine enamel exposed to Lycasin and sucrose.
abstract: In previous experiments, the sucrose substitute Lycasin has been shown to possess low acidogenic potential. Intra-oral cariogenicity tests were carried out in humans to explore the enamel softening effects of Lycasin, using sucrose and saline as controls. The results confirmed that Lycasin would be preferred to sucrose as a sweetener for confections and medicines, although some softening of enamel by Lycasin was evident when compared to the saline controls. The magnitude of this enamel change was small and of doubtful clinical significance.
authors.affiliation: Department of Restorative Dentistry, School of Dentistry, University of Otago, Dunedin, New Zealand.
authors.forename: N P
authors.initials: NP
authors.lastname: Chandler
authors.forename: M E
authors.initials: ME
authors.lastname: Thomson
authors.forename: C W
authors.initials: CW
authors.lastname: Thomson
authors.forename: M M
authors.initials: MM
authors.lastname: Ferguson
mesh_terms: D000328:Adult; D000818:Animals; D002417:Cattle; D003743:Dental Enamel / Q000187:drug effects*; D005260:Female; D006245:Hardness Tests; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D013395:Sucrose / Q000494:pharmacology; D013402:Sugar Alcohols / Q000494:pharmacology*; D013549:Sweetening Agents / Q000494:pharmacology*
chemical_list: D013402:Sugar Alcohols; D013549:Sweetening Agents; D013395:Sucrose; C014646:Lycasin