title: [ERCP under ceftriaxone antibiotic cover in patients with obstructive jaundice].
abstract: The risk of cholangitis after ERCP has been reported to occur in up to 50% of patients with obstructive jaundice. Prophylactic antibiotics have therefore been advocated to reduce the risk. Here we report on the results of 46 patients with obstructive jaundice who were given 1 g of Ceftriaxone i.v. 30 to 60 min. prior to the procedure. Only one patient developed cholangitis with septicemia, which was treated conservatively. No side effects were observed in this group of patients. It is suggested that Ceftriaxone is an adequate prophylactic method to prevent cholangitis and septicemia in patients with obstructive jaundice.
authors.affiliation: Abteilung für Gastroenterologie, Kantonsspital Basel.
authors.forename: B
authors.initials: B
authors.lastname: Werth
authors.forename: G A
authors.initials: GA
authors.lastname: Stalder
authors.forename: U
authors.initials: U
authors.lastname: Marbet
authors.forename: K
authors.initials: K
authors.lastname: Gyr
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002443:Ceftriaxone / Q000627:therapeutic use*; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000009:adverse effects; D002761:Cholangitis / Q000209:etiology / Q000517:prevention & control; D002779:Cholestasis / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011292:Premedication
chemical_list: D002443:Ceftriaxone
vernacular_title: ERCP unter antibiotischem Schutz mit Ceftriaxon bei Patienten mit Verschlussikterus.