Recombinant interleukin-2-induced regression of pulmonary metastasis of renal cell carcinoma.
A patient having renal cell carcinoma with multiple pulmonary metastasis was treated with recombinant interleukin-2. Pulmonary metastatic nodes were markedly diminished. The response was maintained for 4 months. At Autopsy, many fibrotic areas in which metastatic carcinoma was thought to have previously existed and then healed were observed in the bilateral pulmonary lobes, although a few microscopically tiny metastatic lesions still remained.
Fujioka
T
T
Department of Urology, Iwate Medical University School of Medicine, Morioka, Japan.
Tanji
S
S
Koike
H
H
Kumagai
K
K
Kubo
T
T
Ohhori
T
T
Satoh
T
T
Satodate
R
R
D002292:Carcinoma, Renal Cell / Q000556:secondary* / Q000628:therapy*; D005260:Female; D006801:Humans; D007376:Interleukin-2 / Q000627:therapeutic use*; D007680:Kidney Neoplasms; D008175:Lung Neoplasms / Q000556:secondary* / Q000628:therapy; D008875:Middle Aged; D011994:Recombinant Proteins / Q000627:therapeutic use
D007376:Interleukin-2; D011994:Recombinant Proteins