Duplication of euchromatin without phenotypic effects: a variant of chromosome 16.
A family with an unusual variant of chromosome 16 is presented. The mother and son both with additional material present in the short arm of chromosome 16 adjacent to the centromere are phenotypically normal. The extra C-band negative region has been shown not to be composed of alpha satellite DNA. The literature regarding other familial cases of what appears to be the same variant of chromosome 16 is reviewed.
Bryke
C R
CR
Department of Human Genetics, Yale University School of Medicine, New Haven, Connecticut 06510-8005.
Breg
W R
WR
Potluri
V R
VR
Yang-Feng
T L
TL
D000328:Adult; D002843:Chromatin / Q000648:ultrastructure*; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002885:Chromosomes, Human, Pair 16; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male; D010641:Phenotype; D011247:Pregnancy
D002843:Chromatin