title: [Single preoperative intravenous dose of metronidazole for appendectomy in children].
abstract: One hundred children were prophylactically treated with 15 mg/kg-1 of metronidazole immediately before appendicectomy and retrospectively compared with 100 other patients without any antibioprophylaxis. No statistically significant difference was found between the two groups as regards age, weight, sex and macroscopic appearance of the appendix. The overall incidence of complications was 1% in the antibioprophylactic group and 9% in the control group. Furthermore, a single pre-operative intravenous dose of metronidazole was as effective as conventional antibioprophylaxis.
authors.affiliation: Département d'Anesthésie Réanimation, CHRU Dupuytren, Limoges.
authors.forename: A
authors.initials: A
authors.lastname: Lansade
authors.forename: G
authors.initials: G
authors.lastname: Terrier
authors.forename: B
authors.initials: B
authors.lastname: Longis
authors.forename: D
authors.initials: D
authors.lastname: Moulies
authors.forename: J L
authors.initials: JL
authors.lastname: Alain
authors.forename: A
authors.initials: A
authors.lastname: Fouillard
mesh_terms: D001062:Appendectomy; D002648:Child; D005260:Female; D006801:Humans; D007239:Infections / Q000453:epidemiology; D007262:Infusions, Intravenous; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000453:epidemiology; D011292:Premedication; D012189:Retrospective Studies
chemical_list: D008795:Metronidazole
vernacular_title: Antibioprophylaxie par dose unique de métronidazole pour appendicectomie chez l'enfant.