title: Immunologic conditions and infectious complications in colon and rectal surgery for neoplasms.
abstract: The authors evaluated the peroperative immunologic state of patients with colorectal tumors and controlled the postoperative incidence of infections. Twenty-one patients were studied, and delayed type hypersensitivity reactivity determined by the CMI multitest (Merieux) eight days before and eight days after surgery. A lymphocytogram was performed using monoclonal antibodies. A significant percentage of patients were anergic preoperatively. Immunologic analysis revealed lymphocytosis in the first postoperative period. The largest absolute quantitative increase was shown by NK CD16+ cells. It is possible that the results, obtained by dynamic monitoring of the main parameters of cellular immunity, will offer a new way for prognostic evaluation of surgical risk.
authors.affiliation: General Surgery Division, Mauriziano Hospital, Torino, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Fragapane
authors.forename: G
authors.initials: G
authors.lastname: Varvello
authors.forename: M
authors.initials: M
authors.lastname: Bossotti
authors.forename: V
authors.initials: V
authors.lastname: Vergara
authors.forename: G
authors.initials: G
authors.lastname: Poccardi
mesh_terms: D000328:Adult; D000368:Aged; D015179:Colorectal Neoplasms / Q000276:immunology* / Q000601:surgery*; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology; D007111:Immunity, Cellular; D007239:Infections / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012307:Risk Factors; D013601:T-Lymphocytes / Q000276:immunology