title: Developmentally regulated interactions of liver nuclear factors with the rat phosphoenolpyruvate carboxykinase promoter.
abstract: A sequential pattern of interactions of trans-acting factors in rat liver with the phosphoenolpyruvate carboxykinase promoter during late development was observed. A liver-enriched factor, possibly AF1, interacted with the promoter in fetal liver, whereas a factor with the characteristics of C/EBP bound the promoter after birth with the onset of the gene expression.
authors.affiliation: Department of Developmental Biochemistry, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
authors.forename: M
authors.initials: M
authors.lastname: Trus
authors.forename: N
authors.initials: N
authors.lastname: Benvenisty
authors.forename: H
authors.initials: H
authors.lastname: Cohen
authors.forename: L
authors.initials: L
authors.lastname: Reshef
mesh_terms: D000367:Age Factors; D000818:Animals; D001483:Base Sequence; D005786:Gene Expression Regulation; D008099:Liver / Q000254:growth & development / Q000502:physiology*; D008969:Molecular Sequence Data; D009687:Nuclear Proteins / Q000502:physiology*; D010729:Phosphoenolpyruvate Carboxykinase (GTP) / Q000235:genetics*; D011401:Promoter Regions, Genetic; D051381:Rats; D012045:Regulatory Sequences, Nucleic Acid; D014157:Transcription Factors / Q000502:physiology*; D014158:Transcription, Genetic
chemical_list: D009687:Nuclear Proteins; D014157:Transcription Factors; D010729:Phosphoenolpyruvate Carboxykinase (GTP)