Transient lymphoblastosis and thrombocytopenia in Gianotti-Crosti syndrome.
Gianotti-Crosti Syndrome, or papular acrodermatitis of childhood, represents a characteristic rash that is irregularly associated with hepatitis B infection. The authors report papular acrodermatitis in a 10-month-old child with leukopenia, thrombocytopenia, circulating lymphoblasts, and acute anicteric hepatitis B. Physical examination revealed a densely distributed papular rash on the patient's extremities and face and neck, but not on his trunk, buttocks, palms, or soles. Laboratory investigation revealed a normal bone marrow and positive hepatitis B serology. This case reinforces the fact that hematologic findings should not dissuade the work-up of papular acrodermatitis for hepatitis B or other less commonly associated viruses.
Weinerman
H C
HC
Department of Pediatrics, University of Connecticut Health Center, Farmington.
Weisman
S J
SJ
Cates
K L
KL
D000169:Acrodermatitis / Q000503:physiopathology*; D000208:Acute Disease; D006509:Hepatitis B / Q000503:physiopathology*; D006801:Humans; D007223:Infant; D007970:Leukopenia / Q000503:physiopathology*; D008218:Lymphocytosis; D008297:Male; D013577:Syndrome; D013921:Thrombocytopenia / Q000503:physiopathology*