title: Optochin-resistant variants of Streptococcus pneumoniae.
abstract: Ten Streptococcus pneumoniae clinical isolates, possessing physiologically typical pneumococcal characteristics, showed optochin-susceptible and optochin-resistant colonies around the optochin disk, when tested for optochin susceptibility. Equivocal optochin disk test results should be confirmed by bile solubility, agglutination tests, or both.
authors.affiliation: Servicio de Bacteriologia, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Muñoz
authors.forename: A
authors.initials: A
authors.lastname: Fenoll
authors.forename: D
authors.initials: D
authors.lastname: Vicioso
authors.forename: J
authors.initials: J
authors.lastname: Casal
mesh_terms: D000372:Agglutination Tests; D001646:Bile / Q000382:microbiology; D004352:Drug Resistance, Microbial; D006801:Humans; D011803:Quinine / Q000031:analogs & derivatives* / Q000494:pharmacology; D012995:Solubility; D013296:Streptococcus pneumoniae / Q000187:drug effects* / Q000378:metabolism
chemical_list: C017303:ethylhydrocupreine; D011803:Quinine