Parathyroid carcinoma with steroid-suppressible plasma immunoreactive parathyroid hormone and human chorionic gonadotrophin.
A 31-year old male presented with bone pain, polyuria and a palpable nodule in the neck. Radiological examination showed generalised osteopenia, subperiosteal erosion and presence of bilateral renal stones. The essential chemical pathological changes were increased plasma calcium, mid-molecule immuno-reactive parathyroid hormone (iPTH), human chorionic gonadotrophin (hCG) levels. Surgical excision of the nodule revealed a parathyroid carcinoma. The uniqueness of this case is the steroid-suppressible plasma calcium, iPTH, and hCG levels. The diagnostic implications of the findings are discussed.
Chng
S L
SL
Department of Pathology, Faculty of Medicine, University of Malaya, Kuala, Lumpur.
Krishnan
M M
MM
Ramachandran
Chan
C H
CH
Zain
Z
Z
D000328:Adult; D002118:Calcium / Q000097:blood*; D006063:Chorionic Gonadotropin / Q000032:analysis*; D006801:Humans; D008297:Male; D010281:Parathyroid Hormone / Q000032:analysis*; D010282:Parathyroid Neoplasms / Q000601:surgery*
D006063:Chorionic Gonadotropin; D010281:Parathyroid Hormone; D002118:Calcium