title: Development of keratoconus after contact lens wear. Patient characteristics.
abstract: A retrospective review of 398 eyes of 199 patients with keratoconus revealed 106 eyes of 53 patients with an association between contact lens wear and the development of keratoconus. The absence of keratoconus at the time of contact lens fitting was confirmed by slit-lamp examination, keratometry readings, and manifest refraction. Keratoconus was diagnosed after a mean of 12.2 years of contact lens wear. This group was compared with patients with sporadic keratoconus with either no history of contact lens wear or a history of contact lens wear after the diagnosis. They were older at the time of diagnosis, had central vs decentered cones, and had a tendency toward flatter corneal curvatures. We believe that these patients suggest that long-term contact lens wear is a factor that can lead to keratoconus.
authors.affiliation: Department of Ophthalmology, University of Iowa Hospital, Iowa City 52242.
authors.forename: M S
authors.initials: MS
authors.lastname: Macsai
authors.forename: G A
authors.initials: GA
authors.lastname: Varley
authors.forename: J H
authors.initials: JH
authors.lastname: Krachmer
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D003261:Contact Lenses / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007640:Keratoconus / Q000453:epidemiology / Q000209:etiology*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors