title: Spectral baseline correction using CLEAN.
abstract: Baseline distortion in NMR spectroscopy, caused by the "dead time" between signal excitation and detection, makes quantitative interpretation difficult and is aesthetically displeasing. Here the use of the CLEAN algorithm for deconvolving the effect of signal dead time to produce a distortionless baseline is discussed. Unlike other nonlinear spectral estimation techniques, CLEAN is easy to program, easy to use, quite robust, and fast.
authors.affiliation: Institute of Biomedical Engineering and Medical Informatics, Swiss Federal Institute of Technology and University, Zurich.
authors.forename: G C
authors.initials: GC
authors.lastname: McKinnon
authors.forename: C
authors.initials: C
authors.lastname: Burger
authors.forename: P
authors.initials: P
authors.lastname: Boesiger
mesh_terms: D000465:Algorithms; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008433:Mathematics; D013997:Time Factors