title: [Normal thyroid gland volume and factors which affect it under physiologic conditions].
abstract: The introduction of accurate methods for assessment of the volume of the thyroid gland in vivo into clinical practice is a new aspect of the problem of the normal size of the thyroid in healthy subjects. So far we have only vague ideas on its value in the Czechoslovak population. Standards from abroad cannot be adopted mechanically and a local investigation is necessary which will evaluate also the possible persistence of regional differences. The influence of body weight on the volume of the thyroid is accepted in general and this explains also sexual differences. There are no unequivocal views on the effect of age and the stage of the menstrual cycle on the volume of the thyroid gland; few reports on the influence of the season; there is no definite proof of the effect of smoking and alcohol consumption. Precise sonographic measurements did not prove a correlation between the volume of the thyroid gland and basic laboratory parameters (plasma thyroxine, triiodothyronine, thyroglobulin level, level of free fractions of thyroxine and triiodothyronine, globulin binding thyroxine and adenopituitary thyrotropic hormone). So far we do not know when and to what extent omission of these factors distorts diagnostic and therapeutic conclusions.
authors.affiliation: Wýzkumný ústav endokrinologický, Praha.
authors.forename: J
authors.initials: J
authors.lastname: Fexa
authors.forename: J
authors.initials: J
authors.lastname: Nĕmec
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D012016:Reference Values; D013961:Thyroid Gland / Q000033:anatomy & histology* / Q000502:physiology
vernacular_title: Objem normální stítné zlázy a faktory, které jej ovlivnují za fyziologických okolností.