title: [Fatal thrombotic microangiopathy in the mother and fetus].
abstract: The appearance of thrombotic microangiopathy (thrombotic thrombocytopenic purpura, haemolytic uraemic syndrome) could have been documented in a 23 years old pregnant woman, who had been treated previously for immune-thrombocytolytic purpura. The disturbing anamnestic data caused significant delay in correct diagnosis and in starting of fresh-frozen plasma therapy, so the woman and her fetus (in utero) had been died. The specific histological microangiopathic lesions could have been well documented by the autopsy of the mother, however no such alterations could have been detected in the fetus and placenta. This latter intriguing observation might be remarkable in the evaluation of several concepts dealing with the aetiopathogenesis of thrombotic microangiopathy. The short review of literature of thrombotic microangiopathy in pregnancy and puerperial period is also given.
authors.affiliation: Debreceni Orvostudományi Egyetem, II. sz. Belgyógyászati Klinika.
authors.forename: M
authors.initials: M
authors.lastname: Udvardy
authors.forename: B
authors.initials: B
authors.lastname: Telek
authors.forename: A
authors.initials: A
authors.lastname: Kiss
authors.forename: M
authors.initials: M
authors.lastname: Flóra Nagy
authors.forename: T
authors.initials: T
authors.lastname: Mikó
authors.forename: K
authors.initials: K
authors.lastname: Rák
mesh_terms: D005260:Female; D005313:Fetal Death; D006463:Hemolytic-Uremic Syndrome / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis*; D011697:Purpura, Thrombotic Thrombocytopenic / Q000150:complications / Q000175:diagnosis*
vernacular_title: Az anya és a magzat halálához vezetö thrombotikus microangiopathia.