Prenatal detection of simian crease.
We present the prenatal detection of a simian crease (transverse palmar line) in seven fetuses. Three fetuses had trisomy 21, four had normal chromosomes but another anomaly (meningomyelocele, thanatophoric dysplasia, achondroplasia [2]). The technique used and normal anatomy are described.
Jeanty
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Department of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2675.
D000013:Congenital Abnormalities / Q000175:diagnosis*; D003878:Dermatoglyphics; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D011247:Pregnancy; D011296:Prenatal Diagnosis