title: The action of Triton X-100 and sodium dodecyl sulphate on lipid layers. Effect on monolayers and liposomes.
abstract: The action of two detergents, Triton X-100 and sodium dodecyl sulphate (SDS), on large, unilamellar liposomes was determined as liposome size variation, polydispersity and ability to release a soluble marker from liposomes. Triton X-100 produced stronger effects than SDS. Nevertheless, these differences in behaviour of such detergents could not be deduced from the interaction of the detergents with monolayers of the same composition as liposomes.
authors.affiliation: Unitat de Fisicoquímica, Facultat de Farmàcia, Avda. Diagonal s/n, Barcelona, Catalonia, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Hernández-Borrell
authors.forename: M
authors.initials: M
authors.lastname: Pons
authors.forename: J C
authors.initials: JC
authors.lastname: Juarez
authors.forename: J
authors.initials: J
authors.lastname: Estelrich
mesh_terms: D015060:1,2-Dipalmitoylphosphatidylcholine; D055598:Chemical Phenomena; D002621:Chemistry; D002784:Cholesterol; D003902:Detergents; D008081:Liposomes; D008567:Membranes, Artificial; D017830:Octoxynol; D011092:Polyethylene Glycols; D012967:Sodium Dodecyl Sulfate; D013501:Surface-Active Agents
chemical_list: D003902:Detergents; D008081:Liposomes; D008567:Membranes, Artificial; D013501:Surface-Active Agents; D015060:1,2-Dipalmitoylphosphatidylcholine; D012967:Sodium Dodecyl Sulfate; D011092:Polyethylene Glycols; D017830:Octoxynol; D002784:Cholesterol