[Lipids in the lungs and alveolar surfactant in anaphylactic shock].
The process of anaphylactoid response of rats to introduction of egg protein is associated with a decrease of the pulmonary surfactant surface activity. The factors of metabolic surfactant inactivation are as follows: protein accumulation, the disturbance of lipids transport between pulmonary cells and alveolar surface, change in fatty-acidic composition of surfactant phospholipids. The isolation of arachidonic acid from surfactant phospholipids in anaphylactoid shock is an evidence for the participation of the pulmonary surface-active phase in the process of biosynthesis of the lipid mediators in respiratory organs.
Bashmakov
Iu K
IuK
Briuzgina
T S
TS
D000707:Anaphylaxis / Q000209:etiology / Q000378:metabolism*; D000818:Animals; D004527:Egg Proteins; D005227:Fatty Acids / Q000032:analysis / Q000378:metabolism; D050356:Lipid Metabolism; D008055:Lipids / Q000032:analysis; D008168:Lung / Q000378:metabolism*; D008297:Male; D010743:Phospholipids / Q000032:analysis / Q000378:metabolism; D011650:Pulmonary Alveoli / Q000378:metabolism; D011663:Pulmonary Surfactants / Q000032:analysis / Q000378:metabolism*; D051381:Rats
D004527:Egg Proteins; D005227:Fatty Acids; D008055:Lipids; D010743:Phospholipids; D011663:Pulmonary Surfactants
Lipidy legkogo i al'veoliarnogo surfaktanta pri anafilakticheskom shoke.