Three new primary pelvic carcinomas in a patient following radiotherapy for carcinoma of the cervix. Case report.
A 67-year-old woman developed three separate pelvic malignancies forty years after undergoing radiotherapy for a squamous cell carcinoma of the cervix. Although previous exposure to ionising radiation is associated with certain malignancies, review of the literature indicates that there is no strong evidence to support such an association with urothelial or colorectal malignancy.
Gatzen
C
C
Academic Surgical Unit, St. Mary's Hospital, London, United Kingdom.
Vipond
M N
MN
Fish
D E
DE
Snell
M E
ME
D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D001918:Brachytherapy; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy*; D002295:Carcinoma, Transitional Cell / Q000473:pathology*; D005260:Female; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009381:Neoplasms, Radiation-Induced / Q000473:pathology*; D011183:Postoperative Complications / Q000473:pathology; D012004:Rectal Neoplasms / Q000473:pathology*; D012006:Rectovaginal Fistula / Q000473:pathology; D012007:Rectum / Q000473:pathology / Q000528:radiation effects; D001743:Urinary Bladder / Q000473:pathology / Q000528:radiation effects; D001749:Urinary Bladder Neoplasms / Q000473:pathology*; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*