[Protein phosphorylation during mast cell secretion in radioprophylaxis].
A study was made of the role of protein phosphorylation of mast cells and their cytoskeleton upon secretion induced by biogenic amines (histamine and serotonin) and bradykinin, a possible mediator of the effect of MEA, a sulfur-containing radioprotector. The data obtained indicate that the incorporation of phosphate in some proteins of mast cells is an important stage in the process of exocytosis during radioprophylaxis. Cytoskeletal proteins were shown to be involved in mast cell secretion.
Dulin
N O
NO
Kravtsov
G M
GM
Graevskaia
E E
EE
Kudriashov
Iu B
IuB
D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology; D003598:Cytoskeletal Proteins / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects; D008297:Male; D008407:Mast Cells / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects; D010766:Phosphorylation / Q000528:radiation effects; D011837:Radiation-Protective Agents / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
D003598:Cytoskeletal Proteins; D011837:Radiation-Protective Agents
Fosforilirovanie belkov v protsesse sekretsii tuchnykh kletok v usloviiakh radioprofilaktiki.