title: A case of renal lymphangioma with a karyotype 45,X,-X,i dic(7q).
abstract: Cytogenetic analysis of a polycystic unilateral renal lymphangioma was performed by short-term culture and banding methods. The tumor's cells showed an isochromosome of the long arm of chromosome #7 and monosomy of X chromosome, whereas the peripheral lymphocytes stimulated with phytohemagglutinin showed a normal female karyotype, 46,XX. These karyotypic anomalies suggest that lymphangioma, although clinically benign, may have malignant potential.
authors.affiliation: Department of Medical Genetics, Medical Academy of Lodz, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Debiec-Rychter
authors.forename: B
authors.initials: B
authors.lastname: Kałuzewski
authors.forename: H
authors.initials: H
authors.lastname: Saryusz-Wolska
authors.forename: J
authors.initials: J
authors.lastname: Jankowska
mesh_terms: D002675:Child, Preschool; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D025063:Chromosome Disorders; D002897:Chromosomes, Human, Pair 7; D005260:Female; D006801:Humans; D007621:Karyotyping; D007680:Kidney Neoplasms / Q000235:genetics* / Q000473:pathology; D008202:Lymphangioma / Q000235:genetics* / Q000473:pathology; D012729:Sex Chromosome Aberrations; D014960:X Chromosome