title: Prevalence of antithyroglobulin antibodies detected by enzyme-linked immunosorbent assay of canine serum.
abstract: Antithyroglobulin antibody (ATA) values were higher in dogs with low total serum thyroxine (T4) and triiodothyronine (T3) values than in dogs with T3 and T4 values within reference value limits. In the population studied, Doberman Pinschers were predisposed to the development of ATA; there was no sex predilection for development of ATA. Antithyroglobulin antibodies and thyroid status were evaluated in 2 groups of healthy dogs (n = 30) and in 470 canine serum samples submitted for T3 and T4 value determination. Antithyroglobulin antibodies were evaluated by ELISA, and thyroid status was evaluated by measurement of total serum T3 and T4 by radioimmunoassay.
authors.affiliation: Blanche Saunders Dermatology Laboratory, College of Veterinary Medicine, University of Florida, J. Hillis Miller Health Center, Gainesville 32610-0126.
authors.forename: K M
authors.initials: KM
authors.lastname: Beale
authors.forename: R E
authors.initials: RE
authors.lastname: Halliwell
authors.forename: C L
authors.initials: CL
authors.lastname: Chen
mesh_terms: D000818:Animals; D001323:Autoantibodies / Q000097:blood*; D001947:Breeding; D016009:Chi-Square Distribution; D004283:Dog Diseases / Q000209:etiology; D004285:Dogs / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D007037:Hypothyroidism / Q000209:etiology / Q000662:veterinary; D008297:Male; D011863:Radioimmunoassay; D012737:Sex Factors; D013954:Thyroglobulin / Q000037:antagonists & inhibitors*; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
chemical_list: D001323:Autoantibodies; C006606:anti-thyroglobulin; D014284:Triiodothyronine; D013954:Thyroglobulin; D013974:Thyroxine