title: Trisomy 4 in a case of acute undifferentiated myeloblastic leukemia with hand-mirror cells.
abstract: A case of acute undifferentiated myelocytic leukemic with trisomy 4 is described. The patient is a 61-year-old woman who developed leukemia 4 1/2 years after receiving radiation therapy for uterine carcinoma. Many leukemic cells exhibited hand-mirror configuration after the bone marrow aspirate was left at room temperature overnight. The relationship between trisomy 4 and hand-mirror cells in acute myelocytic leukemia is unknown.
authors.affiliation: Department of Pathology, Louisiana State University Medical Center, New Orleans 70112-1393.
authors.forename: Y S
authors.initials: YS
authors.lastname: Kao
authors.forename: C
authors.initials: C
authors.lastname: McCormick
authors.forename: R
authors.initials: R
authors.lastname: Vial
mesh_terms: D001856:Bone Marrow Examination; D002894:Chromosomes, Human, Pair 4; D005260:Female; D006801:Humans; D007621:Karyotyping; D015479:Leukemia, Myelomonocytic, Acute / Q000209:etiology / Q000235:genetics* / Q000473:pathology; D008875:Middle Aged; D014314:Trisomy; D014594:Uterine Neoplasms / Q000532:radiotherapy