title: Jejunal water and sodium secretion occurs in chronic idiopathic intestinal pseudo-obstruction.
abstract: We observed jejunal water and sodium secretion in two patients with chronic idiopathic intestinal pseudo-obstruction by standard perfusion techniques. The ability of glucose to reverse this secretory state was impaired. These observations suggest that a jejunal secretory state may contribute to the diarrhea in chronic idiopathic intestinal pseudo-obstruction.
authors.affiliation: Department of Gastroenterology, St. Bartholomew's Hospital, West Smithfield, London, U.K.
authors.forename: D D
authors.initials: DD
authors.lastname: Rolston
authors.forename: J B
authors.initials: JB
authors.lastname: Hunt
authors.forename: P D
authors.initials: PD
authors.lastname: Fairclough
authors.forename: M
authors.initials: M
authors.lastname: Wilks
authors.forename: D A
authors.initials: DA
authors.lastname: Levison
authors.forename: M L
authors.initials: ML
authors.lastname: Clark
authors.forename: M J
authors.initials: MJ
authors.lastname: Farthing
mesh_terms: D000328:Adult; D001834:Body Water / Q000378:metabolism*; D002908:Chronic Disease; D003967:Diarrhea / Q000150:complications; D005260:Female; D005947:Glucose / Q000502:physiology; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000150:complications / Q000378:metabolism* / Q000503:physiopathology; D007552:Isotonic Solutions / Q000493:pharmacokinetics; D007583:Jejunum / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism*
chemical_list: D007552:Isotonic Solutions; D012964:Sodium; D005947:Glucose