title: Factors associated with conjunctival intraepithelial neoplasia: a case control study.
abstract: Familial and environmental factors may play a role in the development of conjunctival intraepithelial neoplasia (CIN). Nineteen patients with biopsy-proven CIN completed a questionnaire to evaluate possible predisposing factors. Nineteen age-matched and sex-matched controls completed questionnaires and received slit-lamp examinations. Factors associated with a relatively increased risk of developing CIN included exposure to petroleum products, heavy cigarette smoking, light hair and ocular pigmentation, and family origin in the British Isles, Austria or Switzerland. Non-office and nonprofessional workers were more likely to develop conjunctival intraepithelial neoplasia (p = .05), as were those who were not college graduates (p = .07).
authors.affiliation: Cornea Service, Wills Eye Hospital, Philadelphia, Pa. 19107.
authors.forename: C
authors.initials: C
authors.lastname: Napora
authors.forename: E J
authors.initials: EJ
authors.lastname: Cohen
authors.forename: G I
authors.initials: GI
authors.lastname: Genvert
authors.forename: A C
authors.initials: AC
authors.lastname: Presson
authors.forename: J J
authors.initials: JJ
authors.lastname: Arentsen
authors.forename: R C
authors.initials: RC
authors.lastname: Eagle
authors.forename: P R
authors.initials: PR
authors.lastname: Laibson
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D003230:Conjunctival Neoplasms / Q000453:epidemiology* / Q000208:ethnology / Q000209:etiology / Q000235:genetics; D004522:Educational Status; D004781:Environmental Exposure; D004848:Epithelium; D005127:Eye Color; D005260:Female; D006200:Hair Color; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000453:epidemiology; D012307:Risk Factors; D011795:Surveys and Questionnaires