Competitive inhibition of lipolytic enzymes. II. Preparation of 'monoacylamino' phospholipids.
This paper describes the synthesis of a number of phosphatidylcholines and phosphatidylglycols, in which one fatty acyl ester group is replaced by an acylamino function. The phospholipids, both of the alpha- and beta-type, are prepared in racemic and enantiomeric pure forms.
Dijkman
R
R
Department of Biochemistry, State University of Utrecht, The Netherlands.
Dekker
N
N
de Haas
G H
GH
D001667:Binding, Competitive; D055598:Chemical Phenomena; D002621:Chemistry; D004791:Enzyme Inhibitors; D008066:Lipolysis; D015394:Molecular Structure; D010713:Phosphatidylcholines / Q000138:chemical synthesis*; D010715:Phosphatidylglycerols / Q000138:chemical synthesis*; D011412:Propanolamines; D011409:Propylene Glycols; D013237:Stereoisomerism
D004791:Enzyme Inhibitors; D010713:Phosphatidylcholines; D010715:Phosphatidylglycerols; D011412:Propanolamines; D011409:Propylene Glycols; C063408:1-aminopropanediol