[The effect of local UHF hyperthermia and a fractionated radiation dosage on the incidence of perichondritis during the treatment of laryngeal cancer].
Perichondritis in patients treated by a continuous course were noted in 12.5 +/- 1.5%, in patients treated by a split method--in 4.6 +/- 1.2%, in chemoradiotherapy--in 5.75 +/- 1.3%, in thermoradiotherapy--in 3.0 +/- 2.9%, and after synchronization using 5-FU and large fractions--in 30.5 +/- 3.9%. Complications appeared mainly during the 1st year (85%), after 2-3 yrs.--in 8.4%, later on--in 6.6%. Local hyperthermia did not cause an increase in the number of complications.
Vakker
A V
AV
Puchinina
E A
EA
D000328:Adult; D003131:Combined Modality Therapy; D005472:Fluorouracil / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D006979:Hyperthermia, Induced / Q000009:adverse effects*; D015994:Incidence; D007818:Laryngeal Diseases / Q000453:epidemiology* / Q000209:etiology; D007822:Laryngeal Neoplasms / Q000150:complications* / Q000628:therapy; D008875:Middle Aged; D011832:Radiation Injuries / Q000453:epidemiology* / Q000209:etiology; D011878:Radiotherapy / Q000009:adverse effects*; D011879:Radiotherapy Dosage
D005472:Fluorouracil
Vliianie lokal'noĭ SVCh-gipertermii i fraktsionirovaniia dozy izlucheniia na chastotu perikhondritov pri lechenii raka gortani.