title: [Gangliocytic paraganglioma of the duodenum. Case report with immunocytochemical characterization].
abstract: Described in this paper are histological, electron-microscopic, and immunocytochemical findings recorded from a duodenal gangliocytic paraganglioma in a 21-year old man. The sessile polypoid tumor consisted of epithelial cells, neuroid spindle cells, and gangliocytic elements. Neurosecretory granules were detected by electron-microscopy in the epithelial cells. The neuroid spindle cells exhibited the ultrastructural feature of Schwann cells. The tumor was immunocytochemically characterized by the S-100-reactivity of the spindle cells and numerous PP-reactive epithelial cells. Gangliocytic paragangliomas of the duodenum are of benign behaviour and should be removed by local excision.
authors.affiliation: Institut für Pathologische Anatomie, Wilhelm-Pieck-Universität Rostock, DDR.
authors.forename: M
authors.initials: M
authors.lastname: Barten
authors.forename: G
authors.initials: G
authors.lastname: Klöppel
mesh_terms: D000328:Adult; D004379:Duodenal Neoplasms / Q000032:analysis / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D010235:Paraganglioma / Q000032:analysis / Q000473:pathology* / Q000648:ultrastructure
vernacular_title: Das gangliozytische Paragangliom des Duodenums. Fallbericht mit immunzytochemischer Charakterisierung.