Plasma 3-methoxy-4-hydroxyphenylglycol in manic patients: relationships with clinical variables.
Plasma levels of 3-methoxy-4-hydroxyphenylglycol (MHPG) were found to be significantly higher in manic patients than in age- and sex-matched normal controls (n = 22). In 18 manic patients plasma MHPG correlated with manic symptoms but not with anxiety, depression, motor behaviour, acute psychosis, schizophrenia and severity of illness. A positive correlation between MHPG and grandiosity items on rating scales suggests a link with cognitive contents and therefore a relationship with central factors.
Azorin
J M
JM
Department of Psychiatry, Timone Hospital, Marseille, France.
Pupeschi
G
G
Valli
M
M
Joanny
P
P
Raucoules
D
D
Lancon
C
C
Tissot
R
R
D000293:Adolescent; D000328:Adult; D001714:Bipolar Disorder / Q000097:blood*; D003071:Cognition / Q000502:physiology; D005260:Female; D006018:Glycols / Q000097:blood*; D006801:Humans; D008297:Male; D008734:Methoxyhydroxyphenylglycol / Q000097:blood*; D008875:Middle Aged
D006018:Glycols; D008734:Methoxyhydroxyphenylglycol