Ocular amyloidosis: clinical points learned from one case.
The etiology of bilateral vitreous opacification in a 72-year-old man was undiagnosed until after a second vitrectomy when the aspirate was tested with Congo red and found to stain for amyloid. Failure to recognize the significance of a mild peripheral neuropathy delayed the diagnosis. Visual acuity OU remained 20/40 for one year after completion of multiple ocular surgeries. Experience from this case suggests that amyloidosis should be considered in all patients with unexplained vitreous infiltration. A conjunctival biopsy may be helpful diagnostically, and removal of as much cortical and retrolental vitreous as is safe may reduce the incidence of reopacification.
Bene
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Christ Hospital, Cincinnati, OH.
Kranias
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D000368:Aged; D000686:Amyloidosis / Q000150:complications* / Q000473:pathology; D002386:Cataract / Q000209:etiology; D005128:Eye Diseases / Q000209:etiology*; D006801:Humans; D008297:Male; D012163:Retinal Detachment / Q000209:etiology / Q000601:surgery; D012591:Scleral Buckling; D014792:Visual Acuity; D014821:Vitrectomy; D014822:Vitreous Body / Q000473:pathology*