5q deletion. The sole chromosome change in a carcinoma of the bladder.
Direct chromosome preparations of a transitional cell carcinoma of the bladder that had invaded the mucosa but not more deeply showed a 46,XY,5q- karyotype in nearly all metaphases. This is the first description of a 5q deletion, which may have been interstitial, del(5)(q13q22), as the only change in a bladder carcinoma.
Atkin
N B
NB
Department of Cancer Research, Mount Vernon Hospital, Northwood, Middlesex, England.
Fox
M F
MF
D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000235:genetics / Q000473:pathology; D002872:Chromosome Deletion; D002895:Chromosomes, Human, Pair 5; D006801:Humans; D007621:Karyotyping; D008297:Male; D001749:Urinary Bladder Neoplasms / Q000235:genetics* / Q000473:pathology