title: A primary map of 24 loci on human chromosome 16.
abstract: A primary genetic map of chromosome 16 has been constructed by linkage analysis of 24 polymorphic loci, typed in 59 reference families. These loci form a continuous map that covers the whole chromosome and spans genetic distances of 187 cM in males and 226 cM in females. Most of the sex-specific recombination rate difference comes from a nontelomeric region that covers 10 cM in males and 74 cM in females. Both telomeric regions show the opposite trend, with a significant increase in the male recombination rate.
authors.affiliation: Howard Hughes Medical Institute, University of Utah School of Medicine, Salt Lake City 84132.
authors.forename: C
authors.initials: C
authors.lastname: Julier
authors.forename: Y
authors.initials: Y
authors.lastname: Nakamura
authors.forename: M
authors.initials: M
authors.lastname: Lathrop
authors.forename: P
authors.initials: P
authors.lastname: O'Connell
authors.forename: M
authors.initials: M
authors.lastname: Leppert
authors.forename: T
authors.initials: T
authors.lastname: Mohandas
authors.forename: J M
authors.initials: JM
authors.lastname: Lalouel
authors.forename: R
authors.initials: R
authors.lastname: White
mesh_terms: D002873:Chromosome Fragility; D002874:Chromosome Mapping; D002885:Chromosomes, Human, Pair 16 / Q000648:ultrastructure; D005260:Female; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D008297:Male; D011995:Recombination, Genetic; D012737:Sex Factors
chemical_list: D005819:Genetic Markers