title: Loss of nerve fibres in the corpus callosum of progressive subcortical vascular encephalopathy.
abstract: The nerve fibres of the corpus callosum were studied by electron microscopy in five elderly patients with progressive subcortical vascular encephalopathy (PSVE) and compared with those in six age-matched controls. The number of nerve fibres per unit area of the corpus callosum was decreased in PSVE by 18-26%. The loss of nerve fibres in the corpus callosum can play a role in inducing the cognitive deficit of PSVE, on the basis of the loss of nerve fibres in the cerebral hemispheres.
authors.affiliation: Department of Neurology, Tokyo Metropolitan Geriatric Hospital, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Yamanouchi
authors.forename: S
authors.initials: S
authors.lastname: Sugiura
authors.forename: H
authors.initials: H
authors.lastname: Shimada
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003337:Corpus Callosum / Q000648:ultrastructure*; D015140:Dementia, Vascular / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009412:Nerve Fibers / Q000648:ultrastructure*