Epilepsy in children with attention deficit disorder: cognitive, behavioral, and neuroanatomic indices.
Our study examined the hypothesis that if epilepsy adversely influences the cognitive and behavioral performance of children, then children with both attention deficit-hyperactivity disorder and epilepsy (ADHD-Sz) should exhibit more severe cognitive and behavioral difficulties and be more likely to demonstrate abnormalities on cranial computed tomography than ADHD children without epilepsy. We compared ADHD-Sz and ADHD patients using a variety of psychologic, behavioral, and educational measures, as well as cranial computed tomography. ADHD-Sz children scored significantly below the ADHD group on the Wechsler Intelligence Scale for Children-Revised (performance and full scale scores). In both ADHD-Sz and ADHD groups, the prevalence of learning disabilities (LD) and a variety of behavioral features were similar. Neither seizure disorder nor ADHD was associated with an increased incidence of structural abnormalities or asymmetries of the brain. These findings support the belief that epilepsy adversely affects IQ but does not appear to affect the prevalence of LD or behavioral abnormalities in ADHD children. They further support the accumulating body of data demonstrating normal brain anatomy in ADHD by computed tomography.
Kinney
R O
RO
Department of Internal Medicine, Park Nicollet Medical Center, Brooklyn Center, Minnesota.
Shaywitz
B A
BA
Shaywitz
S E
SE
Sarwar
M
M
Holahan
J M
JM
D000293:Adolescent; D001289:Attention Deficit Disorder with Hyperactivity / Q000150:complications* / Q000000981:diagnostic imaging; D002648:Child; D002653:Child Behavior Disorders / Q000209:etiology*; D002675:Child, Preschool; D003072:Cognition Disorders / Q000209:etiology*; D004827:Epilepsy / Q000150:complications* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007361:Intelligence Tests; D008297:Male; D014057:Tomography, X-Ray Computed