Glaucoma in oculo-dento-osseous dysplasia.
Two patients with oculo-dento-osseous dysplasia developed glaucoma in infancy or early childhood. Aggressive surgical management resulted in the preservation of vision in both patients in at least one eye. A review of published reports disclosed that glaucoma in oculo-dento-osseous dysplasia develops at different ages and is possibly secondary to a variety of mechanisms. Glaucoma is the main cause of visual loss in this syndrome, for which patients otherwise have a good prognosis for life and intellect. Early screening for glaucoma in oculo-dento-osseous dysplasia is mandatory, especially when there are symptoms that suggest high intraocular pressure.
Traboulsi
E I
EI
Department of Ophthalmology, Children's National Medical Center, Washington, D.C. 20010.
Parks
M M
MM
D000015:Abnormalities, Multiple; D001848:Bone Diseases, Developmental / Q000150:complications*; D002675:Child, Preschool; D005124:Eye Abnormalities / Q000150:complications*; D005260:Female; D005901:Glaucoma / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007223:Infant; D007429:Intraocular Pressure; D011379:Prognosis; D013577:Syndrome; D014071:Tooth Abnormalities / Q000150:complications*