title: The use of magnetic resonance imaging in the diagnosis of pigmented villonodular synovitis.
abstract: Although the clinical and radiographic features of pigmented villonodular synovitis (PVS) have been well described, diagnosis is often delayed and high rates of recurrence after synovectomy are reported. Magnetic resonance imaging (MRI) has been shown to be useful in the diagnosis of soft tissue masses. Three patients with biopsy-proven PVS and radiographs showing only effusion underwent MRI in the axial, coronal, and sagittal planes. The margins of the diseased synovium were best demonstrated on long TR/TE (T2-weighted) images. The synovium contained areas of void signal intensity felt to be due to hemosiderin, interspersed with increased signal from both inflammation and fat. In all cases, the margins of the diseased synovium were clearly delineated, allowing classification as nodular or diffuse. No appreciable change in signal intensity was seen when comparing nodular and diffuse forms. MRI is useful but not specific for PVS, since rheumatoid synovitis may show a similar signal pattern. However, MRI in patients with suspected PVS may decrease the time until diagnosis, aid in preoperative planning and obtaining adequate margins of resection, and may be a non-invasive method of long-term follow up for possible recurrence.
authors.affiliation: Division of Orthopedic Surgery, Duke University Medical Center, Durham, NC 27710.
authors.forename: S C
authors.initials: SC
authors.lastname: Poletti
authors.forename: H S
authors.initials: HS
authors.lastname: Gates
authors.forename: S M
authors.initials: SM
authors.lastname: Martinez
authors.forename: W J
authors.initials: WJ
authors.lastname: Richardson
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007717:Knee / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D012008:Recurrence; D013585:Synovitis / Q000175:diagnosis*; D013586:Synovitis, Pigmented Villonodular / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery