Impaired verbal reasoning and constructional apraxia in subjects with right hemisphere damage.
In addition to causing visuospatial deficits, damage to the right cerebral hemisphere also impairs other cognitive abilities, including those requiring higher-order aspects of language. The present study used a standardized test battery to examine the relationship between visuospatial abilities and comprehension of narrative material in subjects having unilateral right hemisphere damage (RHD). In a series of 41 consecutively admitted RHD subjects, impairments in abstracting information from narrative passages were as prevalent and as severe in magnitude as constructional apraxia. Moreover, the extent of the visuospatial and linguistic impairments were highly correlated. Although age, educational levels, and degree of premorbid brain atrophy were all found to influence performance, analysis of a select subgroup of the population established that the covariation of visuospatial and verbal impairments is related to right hemisphere damage per se. Clinically, these findings may be of significance for understanding the pervasive cognitive impairments that are often evidenced by RHD patients.
Benowitz
L I
LI
Department of Psychiatry, Harvard Medical School, Belmont, Massachusetts.
Moya
K L
KL
Levine
D N
DN
D000368:Aged; D001072:Apraxias / Q000503:physiopathology*; D001925:Brain Damage, Chronic / Q000175:diagnosis / Q000503:physiopathology*; D002561:Cerebrovascular Disorders / Q000503:physiopathology; D003210:Concept Formation / Q000502:physiology*; D004292:Dominance, Cerebral / Q000502:physiology*; D006801:Humans; D011939:Mental Recall / Q000502:physiology; D008875:Middle Aged; D011597:Psychomotor Performance / Q000502:physiology*; D012193:Reversal Learning / Q000502:physiology; D012691:Serial Learning / Q000502:physiology; D013067:Speech Perception / Q000502:physiology*; D014057:Tomography, X-Ray Computed