title: [Mitral valve replacement in young children: a long-term follow-up].
abstract: The Authors report follow-up data (mean 60, range 13-101 months) from 4 patients under two years of age (mean 11.5 months) operated on for prosthetic mitral valve implantation. Two patients were male and two female. Pre-operative diagnosis was partial atrioventricular septal defect with parachute mitral valve in one case and isolated mitral valve anomaly in the others (1 parachute, 2 hammock valves). One bioprosthesis (Liotta n. 23) and three mechanical prostheses (Björk-Shiley) were implanted. Complications occurred in two patients: one case of endocarditis on the bioprosthesis, leading to substitution with a Björk-Shiley valve; one case of acute thrombosis 8 months after implantation in the only pt receiving aspirin as prophylactic therapy. This complication was resolved by intravenous thrombolytic agents. All the patients are alive, in I NYHA functional class and receiving oral anti-coagulants. Instrumental follow-up with eco-Doppler demonstrated normal functioning prostheses in all the patients. A sub-aortic gradient was found in the patient with partial atrioventricular septal defect. Prosthesis-patient mismatch was identified in a patient operated on when she was 6 months old who was followed-up for 5 years.
authors.affiliation: Divisione di Cardiologia, P.O. Casa del Sole, Palermo.
authors.forename: R
authors.initials: R
authors.lastname: Grillo
authors.forename: A
authors.initials: A
authors.lastname: Rubino
authors.forename: S
authors.initials: S
authors.lastname: Pipitone
authors.forename: D
authors.initials: D
authors.lastname: Pieri
authors.forename: M
authors.initials: M
authors.lastname: Donzelli
authors.forename: L
authors.initials: L
authors.lastname: Patanè
authors.forename: V
authors.initials: V
authors.lastname: Sperandeo
mesh_terms: D001705:Bioprosthesis; D002648:Child; D002675:Child, Preschool; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis; D006801:Humans; D007223:Infant; D008297:Male; D008943:Mitral Valve / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000601:surgery; D008946:Mitral Valve Stenosis / Q000601:surgery; D013997:Time Factors
vernacular_title: Sostituzione valvolare mitralica nella prima infanzia: follow-up a lungo termine.