The effect of human chorionic gonadotropin (HCG) on restoration of physiological continuity of the spinal cord. A preliminary report.
The effect of human chorionic gonadotropin (HCG) hormone on restoration of physiological continuity of the spinal cord in rats was studied. After complete transection of the spinal cord at the midthoracic level eleven of these 21 rats in the study received HCG for six weeks. The other ten served as controls. At the end of six weeks amplitude of the cortically evoked motor At the end of six weeks amplitude of the cortically evoked motor action potential (CEMAP) was measured. The amplitude of the motor action potentials was significantly greater (P less than 0.02) in HCG treated rats. The study thus shows that HCG might help in the restoration of spinal cord function.
Patil
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Division of Neurosurgery, University of Nebraska Medical Center, Omaha 68105.
Filmore
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K
Hill
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D000818:Animals; D006063:Chorionic Gonadotropin / Q000494:pharmacology / Q000627:therapeutic use*; D005071:Evoked Potentials / Q000502:physiology; D051381:Rats; D013116:Spinal Cord / Q000187:drug effects* / Q000502:physiology; D013119:Spinal Cord Injuries / Q000188:drug therapy*
D006063:Chorionic Gonadotropin