Inhibition by sodium citrate on 67Ga adsorption to various materials.
The adsorption of 67Ga to the inner surface of stainless steel, polyethylene and silicone tubings was studied. The three tubings remarkably adsorbed 67Ga in order of stainless steel, silicone and polyethylene tubing. Sodium citrate inhibited the adsorption of 67Ga in a dose-dependent manner. These phenomena were also observed in blood sampling via the catheter inserted into the external jugular vein. These results show that constant concentration of sodium citrate is necessary for the in vitro study of 67Ga in order to prevent the adsorption to the surface of experimental materials.
Kohno
H
H
Department of Radiopharmacy, Tohoku College of Pharmacy, Sendai-shi, Japan.
Katoh
S
S
Ohkubo
Y
Y
Kubodera
A
A
D000327:Adsorption; D000818:Animals; D002406:Catheterization, Peripheral; D002951:Citrates; D019343:Citric Acid; D005708:Gallium; D005710:Gallium Radioisotopes; D008297:Male; D011095:Polyethylenes; D051381:Rats; D011919:Rats, Inbred Strains; D012828:Silicones; D013193:Stainless Steel
D002951:Citrates; D005710:Gallium Radioisotopes; D011095:Polyethylenes; D012828:Silicones; D013193:Stainless Steel; D019343:Citric Acid; C034163:gallium chloride; D005708:Gallium