title: Expression of villin in the mouse oviduct and the seminiferous ducts.
abstract: Villin, a 95-kD cytoskeletal protein selectively expressed in the microvilli of some absorptive cells was localized immunohistochemically in the oviduct and the seminiferous excretory ducts of the mouse. Villin was found in the proximal part of the oviduct, comprising the preampulla, ampulla, and part of the isthmus. Distal to the isthmus the oviductal cells lining the junctura and the intrauterine colliculus tubaris were devoid of villin. No villin could be detected in the uterine cells. Ductuli efferentes, connecting the rete testis with the epididymis were the only portion of the male seminiferous ductal system expressing villin. The cells lining the epididymis and the vas deferens were devoid of villin. These data show that villin is selectively expressed in male and female reproductive systems and that it is limited to anatomically defined proximal portions of the reproductive ducts.
authors.affiliation: Department of Pathology and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107.
authors.forename: B
authors.initials: B
authors.lastname: Horvat
authors.forename: M
authors.initials: M
authors.lastname: Osborn
authors.forename: I
authors.initials: I
authors.lastname: Damjanov
mesh_terms: D000818:Animals; D002352:Carrier Proteins / Q000096:biosynthesis*; D005187:Fallopian Tubes / Q000378:metabolism*; D005260:Female; D007150:Immunohistochemistry; D008297:Male; D051379:Mice; D008840:Microfilament Proteins / Q000096:biosynthesis*; D012671:Seminiferous Tubules / Q000378:metabolism*; D013737:Testis / Q000378:metabolism*
chemical_list: D002352:Carrier Proteins; D008840:Microfilament Proteins; C026615:villin