[Effect of the antihypoxic agent ionol on the morphofunctional state of the air-blood barrier of the lungs in hypoxic anoxia].
It is shown that antihypoxic ionol has promoted normalization of the air-blood lung barrier ultrastructure, activation of the surfactant system under acute hypoxic hypoxia effect as well as compensatory redistribution of the thickness of separate barrier layers due to intensified synthesis of phospholipids which are the components of cytoplasmic membranes and pulmonary surfactant.
Rozova
E V
EV
Dubovaia
M G
MG
D000818:Animals; D015824:Blood-Air Barrier / Q000187:drug effects* / Q000502:physiology; D002084:Butylated Hydroxytoluene / Q000627:therapeutic use*; D000860:Hypoxia / Q000188:drug therapy* / Q000473:pathology; D008168:Lung / Q000502:physiology* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D010101:Oxygen Consumption / Q000187:drug effects*; D011663:Pulmonary Surfactants / Q000187:drug effects / Q000502:physiology; D051381:Rats
D011663:Pulmonary Surfactants; D002084:Butylated Hydroxytoluene
Vliianie antigipoksanta ionola na morfofunktsional'noe sostoianie aérogematicheskogo bar'era legkikh pri gipoksicheskoĭ.