Misinterpretation of iodine uptake in papillary thyroid carcinoma and primary lung adenocarcinoma.
This is the first case report of an iodine-storing metastasising carcinoma of extrathyroidal origin and the simultaneous presence of a papillary thyroid carcinoma. In the course of the disease, an increase in pathological iodine uptake was observed after repeated iodine-131 ablation, so that the original tentative diagnosis of a metastasising, differentiated thyroid carcinoma appeared to be confirmed; moreover, the histological work-up of a femur metastasis--without adequate immunohistochemical assessment--was misinterpreted. What is also remarkable about this case report is a pathological iodine-131 uptake both in the extrathyroidal primary tumor and the metastases.
Langsteger
W
W
Internal Department Barmherzige Brüder Graz-Eggenberg Hospital Graz, Austria.
Lind
P
P
Költringer
P
P
Beham
A
A
Eber
O
O
D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology; D002291:Carcinoma, Papillary / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D005266:Femoral Neoplasms / Q000556:secondary; D006801:Humans; D007457:Iodine Radioisotopes; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging* / Q000473:pathology; D011877:Radionuclide Imaging; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology
D007457:Iodine Radioisotopes