title: Probable assignment of the dihydropteridine reductase gene to 4p15.31.
abstract: We report the dihydropteridine reductase (DHPR) activity in cases with interstitial deletion of the short arm of chromosome 4. Case 1 with the segment 4p15.32-4p16 deleted has normal DHPR activity. Case 2 with 4p15.2-4p15.32 deleted has reduced DHPR activity, less than 50% of normal.
authors.affiliation: Department of Pediatrics, Nagoya City University Medical School.
authors.forename: S
authors.initials: S
authors.lastname: Sumi
authors.forename: T
authors.initials: T
authors.lastname: Ishikawa
authors.forename: Y
authors.initials: Y
authors.lastname: Ito
authors.forename: H
authors.initials: H
authors.lastname: Oishi
authors.forename: K
authors.initials: K
authors.lastname: Asai
authors.forename: Y
authors.initials: Y
authors.lastname: Wada
mesh_terms: D002871:Chromosome Banding; D002872:Chromosome Deletion; D002894:Chromosomes, Human, Pair 4; D004093:Dihydropteridine Reductase / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D009247:NADH, NADPH Oxidoreductases / Q000235:genetics*
chemical_list: D004093:Dihydropteridine Reductase; D009247:NADH, NADPH Oxidoreductases