title: Altromycins, novel pluramycin-like antibiotics. II. Isolation and elucidation of structure.
abstract: A novel complex of Gram-positive antibiotics was produced from the fermentation of an actinomycete culture AB 1246E-26. The antibiotics were recovered from the whole fermentation broth by extraction with organic solvent and isolated using counter-current chromatography. UV and IR data place these compounds in the anthraquinone-derived class of antibiotics. Mass spectral and NMR data indicate a new complex of compounds related to, but distinctly different from the pluramycin type antibiotics.
authors.affiliation: Anti-infective Research Division, Abbott Laboratories, IL 60064.
authors.forename: G M
authors.initials: GM
authors.lastname: Brill
authors.forename: J B
authors.initials: JB
authors.lastname: McAlpine
authors.forename: D N
authors.initials: DN
authors.lastname: Whittern
authors.forename: A M
authors.initials: AM
authors.lastname: Buko
mesh_terms: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000032:analysis / Q000302:isolation & purification*; D002845:Chromatography; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; C063716:altromycin A; C063718:altromycin C; C063717:altromycin B; C063719:altromycin D