title: Polymorphism of plasminogen in Tuscany (Italy).
abstract: The distribution of PLG phenotypes in the population of Tuscany (Central Italy) has been investigated by means of isoelectric focusing followed by immunofixation of desialyzed sera. In a random sample of 383 unrelated healthy blood donors registered at the Hospital of Pisa, three common phenotypes, PLG A, A-B, and B, and two rare variants were found. The allele frequencies calculated in our study were: PLG*A = 0.6749, PLG*B = 0.3225, and PLG*rare = 0.0026. The theoretical exclusion rate in cases of disputed paternity is 17.42%.
authors.affiliation: Dipartimento di Biomedicina, Università, Pisa, Italy.
authors.forename: I
authors.initials: I
authors.lastname: Spinetti
authors.forename: R
authors.initials: R
authors.lastname: Domenici
authors.forename: A
authors.initials: A
authors.lastname: Giari
authors.forename: M
authors.initials: M
authors.lastname: Bargagna
mesh_terms: D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D007558:Italy; D010641:Phenotype; D010958:Plasminogen / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics*
chemical_list: D010958:Plasminogen