High-performance liquid chromatographic assay of iomeprol in plasma and urine.
A high-performance liquid chromatographic method for assaying the radiographic contrast agent iomeprol in plasma and urine samples is described. Before reversed-phase chromatography, the biological fluids are treated with ion-exchange resins and iopamidol is added as internal standard. The compounds are monitored during elution by ultraviolet-visible spectrometry at 245 nm. The method shows good precision and accuracy and gives similar results to X-ray fluorescence analysis.
Lorusso
V
V
Bracco Research Department, Milan, Italy.
Poggesi
I
I
Dal Fiume
D
D
Tirone
P
P
D002851:Chromatography, High Pressure Liquid; D002852:Chromatography, Ion Exchange; D003287:Contrast Media; D006801:Humans; D007479:Iopamidol / Q000032:analysis / Q000031:analogs & derivatives; D015394:Molecular Structure; D011786:Quality Control; D013052:Spectrometry, X-Ray Emission; D013053:Spectrophotometry
D003287:Contrast Media; C057937:iomeprol; D007479:Iopamidol