Involvement of 9p in metastatic ovarian adenocarcinomas.
By a direct method and after in vitro culture, we cytogenetically analyzed five ovarian adenocarcinomas, using six samples of ascitic fluid. The structural aberrations included rearrangements of chromosomes 1 and 3, in agreement with the results of other researchers. The long arm of chromosome 6 was rearranged in three samples, but no translocation t(6;14) was found. Rearrangements involving 9p were present in all cases, with breakpoints at p13 or p22-23.
Bello
M J
MJ
Instituto de Investigaciones Biomédicas del CSIC, Madrid, Spain.
Moreno
S
S
Rey
J A
JA
D000230:Adenocarcinoma / Q000235:genetics* / Q000556:secondary; D002869:Chromosome Aberrations; D002872:Chromosome Deletion; D002899:Chromosomes, Human, Pair 9; D005260:Female; D006801:Humans; D007621:Karyotyping; D010051:Ovarian Neoplasms / Q000235:genetics* / Q000473:pathology; D014407:Tumor Cells, Cultured