[The effect of L-DOPA on the accumulation of lipid peroxidation products in separate brain structures during irradiation].
A study was made of the effect of L-DOPA on the dynamics of changes in lipid peroxidation products (LPP) and the content of various types of SH groups in certain brain structures (oblongata, cerebellum, visual and sensorimotor cortex) and their synaptosomal fractions upon irradiation. The preadministration of L-DOPA to irradiated rats inhibited LPP accumulation, prevented the decrease in the content of various types of thiols and thus exerted an antioxidant effect.
Babaev
R A
RA
Kocharli
R Kh
RKh
Akhmedova
G Sh
GSh
Gasanova
A A
AA
Babaev
Kh F
KhF
D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects*; D003864:Depression, Chemical; D007980:Levodopa / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects* / Q000502:physiology / Q000528:radiation effects*; D051381:Rats; D013438:Sulfhydryl Compounds / Q000378:metabolism / Q000528:radiation effects; D013574:Synaptosomes / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D013997:Time Factors
D013438:Sulfhydryl Compounds; D007980:Levodopa
Vliianie L-DOFA na nakoplenie produktov perekisnogo okisleniia lipidov v otdel'nykh strukturakh mozga pri obluchenii.