title: Model identifying the reproductive decision after genetic counseling.
abstract: To assess the identifiability of reproductive planning after genetic counseling, a model was designed to study 8 relevant factors influencing reproductive decisions after genetic counseling. Altogether, 164 couples were interviewed at home 2 to 3 years after genetic counseling. The factors were arranged in a flow chart distinguishing 3 groups: reproductive outcome prior to genetic counseling, desire to have children, and interpretation of information gained from genetic counseling. The model based upon these retrospective data showed that reproductive decisions were identified correctly in 91% of the cases. The model consisted of 8 factors and documented the urgency of the desire to have children and the interpretation of the genetic risk. In addition, linear discriminant analysis of the 8 relevant factors enabled identification of the reproductive decision in 96% of the cases. This model may prove helpful to counselors and counselees by showing what other couples have decided in comparable circumstances and for which reasons.
authors.affiliation: Department of Clinical Genetics, Erasmus University, Rotterdam, The Netherlands.
authors.forename: P G
authors.initials: PG
authors.lastname: Frets
authors.forename: H J
authors.initials: HJ
authors.lastname: Duivenvoorden
authors.forename: F
authors.initials: F
authors.lastname: Verhage
authors.forename: E
authors.initials: E
authors.lastname: Ketzer
authors.forename: M F
authors.initials: MF
authors.lastname: Niermeijer
mesh_terms: D016002:Discriminant Analysis; D005193:Family Planning Services; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D008297:Male; D008960:Models, Psychological; D009426:Netherlands; D012306:Risk