Temporal fluctuation of the lead level in the cord blood of neonates in Taipei.
From August 1985 to September 1987, 9,502 cord blood samples were obtained from the Taipei Municipal Maternal and Child Hospital. A total of 205 cord blood samples chosen randomly from newborns without parental exposure to lead were analyzed by flameless atomic absorption spectrophotometry. The average blood lead level was .36 +/- .11 mumol/l (7.48 +/- 2.25 micrograms/dl). A similar analysis was performed on samples obtained from 160 newborns whose fathers had occupational lead exposure. In both groups, the average concentration of lead in cord blood in the summer was statistically greater than that in the winter. Air lead and total amount of lead in gasoline consumed in Taipei appeared to be associated with this seasonal fluctuation in the average lead level of cord blood. After considering alternative sources, we conclude that the seasonal fluctuation of cord blood lead is probably influenced by air lead produced from the combustion of gasoline.
Hwang
Y H
YH
Center for Research of Environmental and Occupational Diseases, College of Medicine, National Taiwan University, ROC.
Wang
J D
JD
D000393:Air Pollutants / Q000032:analysis; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage; D004781:Environmental Exposure; D005220:Fathers; D005260:Female; D005312:Fetal Blood / Q000032:analysis*; D005742:Gasoline / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn / Q000097:blood*; D007854:Lead / Q000032:analysis / Q000097:blood*; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011897:Random Allocation; D012621:Seasons; D013624:Taiwan
D000393:Air Pollutants; D004365:Drugs, Chinese Herbal; D005742:Gasoline; D007854:Lead