[Relation between the anti-oxidative potential of psoriasis blood plasma in reactivity of granulocytes].
It was revealed a positive correlation between an antioxidative potential (AP) of blood plasma from psoriasis patients and generation of O2- by normal granulocytes, stimulated by zymosan or aggregated human gamma-globulin, in the presence of the same plasma samples. The AP of plasma was measured by means of inhibition of the chemiluminescence arising during photoautoxidation of luminol. The production of O2- after cell stimulation was estimated by means of the reduction of tetrazolium salt. The result is discussed from the viewpoint of informative-regulatory role of the plasma AP for the white blood cells as a part of the whole organism, participating in its common defence reactions.
Popov
I
I
Institut für Medizinische Immunologie, Bereichs Medizin (Charité), Humboldt-Universität zu Berlin.
Müller
G M
GM
Miehe
M
M
Lewin
G
G
von Baehr
R
R
D000975:Antioxidants / Q000493:pharmacokinetics*; D005260:Female; D005609:Free Radicals; D006098:Granulocytes / Q000276:immunology*; D006801:Humans; D008163:Luminescent Measurements; D008297:Male; D011565:Psoriasis / Q000276:immunology*; D012016:Reference Values
D000975:Antioxidants; D005609:Free Radicals
Die Beziehung zwischen dem antioxidativen Potential des psoriatischen Blutplasmas und der Reaktivität von Granulozyten.