title: [Metaphylaxis and therapy of the MMA syndrome of sows with Baytril].
abstract: The efficiency of antibacterial metaphylaxis and therapy on the control of the MMA-syndrome has been investigated in a large breeding-herd with a total of 828 sows in the study. For this the recently developed quinolone-derivate Baytril was used. Feed medication with furazolidone and sulfadimidine reduced the incidence of disease to 29.7% (control 41.3%), injection of Baytril on the day of parturition reduced it to 10.8% (using a dosage of 1.25 mg/kg body weight) respectively 6.8% (dosage 5 mg/kg). Treatment also resulted in a lower incidence of elevated milk-pH (greater than 6.7). The development of piglets was good in all groups of metaphylaxis. Litters of sows which had been treated with Baytril as prophylaxis or therapy had no low extremes in the weight gains of the piglets. In the treatment of MMA-affected animals Baytril was significantly superior as compared to Trimethoprim-Sulfonamide, if a dosage of 5 mg/kg body weight was used. Using a dosage of 1.25 mg/kg body weight both drugs had the same effect. Even at the end of the five month of the study there was no isolation of bacteria resistant against Baytril.
authors.affiliation: Klinik für Klauentiere, Fortpflanzung und Haltungshygiene des FB Veterinärmedizin, FU Berlin.
authors.forename: G
authors.initials: G
authors.lastname: Schöning
authors.forename: H
authors.initials: H
authors.lastname: Plonait
mesh_terms: D042462:4-Quinolones; D000818:Animals; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D000077422:Enrofloxacin; D004756:Enterobacteriaceae Infections / Q000188:drug therapy / Q000662:veterinary*; D005260:Female; D024841:Fluoroquinolones; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy / Q000662:veterinary*; D015363:Quinolones; D013552:Swine; D013553:Swine Diseases / Q000188:drug therapy*; D013577:Syndrome
chemical_list: D042462:4-Quinolones; D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D015363:Quinolones; D000077422:Enrofloxacin
vernacular_title: Metaphylaxe und Therapie des MMA-Syndroms der Sauen mit Baytril.