[The treatment of laryngeal cancer by using local hyperthermia].
Potentiation of the effect of radiation and combined treatment of laryngeal cancer by local hyperthermia was studied in 43 patients. In 51 cases of the control group (radiotherapy), conventionally-dynamic fractionation of dose was used. At 32 Gy, complete or partial regression of tumor was observed in 72.1% in the study group and 64.7% of controls. An increased frequency of radiation-induced damage of the oral mucosa was observed whereas radiation epidermitis did not occur. Three-year relapse-free survival following a course of radical thermoradiotherapy was as high as 76.5% compared to 40% in controls. Overall three-year survival (including the results of combined treatment and treatment for relapse) increased from 66.7 to 83.3%.
Andreev
V G
VG
Shaimbetov
B O
BO
Kurpeshev
O K
OK
Lopatin
V F
VF
Iglin
A V
AV
Filippov
K G
KG
D000328:Adult; D003131:Combined Modality Therapy; D006801:Humans; D006979:Hyperthermia, Induced / Q000009:adverse effects / Q000379:methods; D007822:Laryngeal Neoplasms / Q000150:complications / Q000401:mortality / Q000628:therapy*; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D011855:Radiodermatitis / Q000453:epidemiology; D011879:Radiotherapy Dosage; D012074:Remission Induction; D013997:Time Factors
Lechenie raka gortani s ispol'zovaniem lokal'noĭ gipertemii.