title: Prevalence of congenital adrenal hyperplasia in Kuwait.
abstract: Between 1978 and 1988 congenital adrenal hyperplasia (CAH) was diagnosed in 60 children in Kuwait with an estimated prevalence of 1:9,000 livebirths, which is higher than that reported from Europe and Canada. In addition, there was presumptive evidence of CAH resulting in the death of 20 other children, giving a prevalence figure of 1:7000. There were 41 girls (68%) and 19 boys (32%). Thirty-one of the girls (75.6%) and 11 of the boys (57.9%) were saltlosers. Fifty-four patients (90%) were diagnosed as 21-hydroxylase deficient, 3 patients (5%) had a deficiency of the 3 beta-hydroxy-steroid dehydrogenase enzyme, and 3 patients (5%) showed a deficiency of 11 beta-hydroxylase.
authors.affiliation: Department of Paediatrics, Farwaniya Hospital, Kuwait.
authors.forename: M M
authors.initials: MM
authors.lastname: Lubani
authors.forename: A R
authors.initials: AR
authors.lastname: Issa
authors.forename: R
authors.initials: R
authors.lastname: Bushnaq
authors.forename: Q A
authors.initials: QA
authors.lastname: al-Saleh
authors.forename: K I
authors.initials: KI
authors.lastname: Dudin
authors.forename: P C
authors.initials: PC
authors.lastname: Reavey
authors.forename: M Y
authors.initials: MY
authors.lastname: el-Khalifa
authors.forename: D S
authors.initials: DS
authors.lastname: Manandhar
authors.forename: Y K
authors.initials: YK
authors.lastname: Abdul Al
authors.forename: E A
authors.initials: EA
authors.lastname: Ismail
mesh_terms: D000312:Adrenal Hyperplasia, Congenital / Q000453:epidemiology* / Q000401:mortality / Q000503:physiopathology; D002170:Canada / Q000453:epidemiology; D002648:Child; D005060:Europe / Q000453:epidemiology; D005260:Female; D006801:Humans; D007730:Kuwait / Q000453:epidemiology; D008297:Male; D015995:Prevalence; D013250:Steroid Hydroxylases / Q000172:deficiency*; D014481:United States / Q000453:epidemiology
chemical_list: D013250:Steroid Hydroxylases