Two brothers with idiopathic membranous nephropathy and familial sensorineural deafness.
Genetic factors could play an important role in the pathogenesis of idiopathic membranous nephropathy, and a few cases of familial membranous nephropathy have been described: an increased incidence of some HLA antigens as DR3 and others has been reported. We present two brothers with idiopathic membranous nephropathy and sensorineural deafness. HLA typing was performed in the two patients and in the members of the family, and it showed the absence of linkage of an HLA antigen with the renal disease in the family.
Meroni
M
M
Unita Operativa di Nefrologia e Dialisi, Ospedale di Vimercate, Università degli Studi, Milano, Italy.
Volpi
A
A
Usberti
M
M
Battini
G
G
Tarelli
L T
LT
Giordano
F
F
Sessa
A
A
D000328:Adult; D003638:Deafness / Q000235:genetics*; D005260:Female; D015433:Glomerulonephritis, Membranous / Q000235:genetics* / Q000473:pathology; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D010375:Pedigree; D010641:Phenotype
D006680:HLA Antigens