title: Cardiovascular screening in Army personnel over age 40 in the State of Hawaii.
abstract: A cardiovascular screening protocol was applied prospectively to 1,900 soldiers over 40 years of age to identify individuals with latent coronary artery disease. Primary screening included a cardiovascular history, physical examination, electrocardiogram, serum cholesterol and serum glucose determinations, and calculated Framingham risk index. Seven hundred ninety-six individuals required secondary screening, consisting of stress testing and cardiac fluoroscopy. The screening process led to coronary angiography in 43 individuals; of these, 17 had obstructive coronary artery disease, ten had nonobstructive coronary artery disease, and 16 had normal coronary arteries. Application of primary screening before exercise testing increased the posttest probability of obstructive coronary artery disease to 50% in the individuals with a positive treadmill test. This is four times the expected value of 11% calculated using Bayes' theorem. The combination of a positive treadmill test and the finding of coronary artery calcification on fluoroscopy was an excellent predictor of obstructive coronary artery disease.
authors.affiliation: Cardiology Clinic, Tripler Army Medical Center, Honolulu, Hawaii.
authors.forename: D C
authors.initials: DC
authors.lastname: Wortham
authors.forename: L W
authors.initials: LW
authors.lastname: Jordan
authors.forename: S L
authors.initials: SL
authors.lastname: Jones
authors.forename: H M
authors.initials: HM
authors.lastname: Thomas
mesh_terms: D000328:Adult; D000367:Age Factors; D001499:Bayes Theorem; D006328:Cardiac Catheterization; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000503:physiopathology / Q000517:prevention & control*; D003327:Coronary Disease / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D004562:Electrocardiography; D005069:Evaluation Studies as Topic; D005260:Female; D005471:Fluoroscopy; D006254:Hawaii / Q000453:epidemiology; D006334:Heart Function Tests / Q000379:methods; D006801:Humans; D015994:Incidence; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D008889:Military Personnel; D011446:Prospective Studies; D012307:Risk Factors