[The mechanism of the radioprotective action of cystamine and mexamine].
It was found that at the time when cystamine and mexamine exert their maximum radioprotective action DNA synthesis rate decreases in bone marrow cells, the ratio between the colony-forming units in the bone marrow and peripheral blood changes, and functional activity of neutrophils increases.
Chigareva
N G
NG
Morozova
I N
IN
Deev
S P
SP
D008735:5-Methoxytryptamine / Q000494:pharmacology*; D000818:Animals; D002452:Cell Count / Q000187:drug effects / Q000528:radiation effects; D003114:Colony-Forming Units Assay; D003538:Cystamine / Q000494:pharmacology*; D004247:DNA / Q000096:biosynthesis / Q000187:drug effects / Q000528:radiation effects; D005720:Gamma Rays; D006412:Hematopoietic Stem Cells / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009504:Neutrophils / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D051381:Rats; D012701:Serotonin / Q000494:pharmacology*
D012701:Serotonin; D008735:5-Methoxytryptamine; D004247:DNA; D003538:Cystamine
K mekhanizmu radiozashchitnogo deĭstviia tsistamina i meksamina.