Dysplastic naevi in association with partial deletion of chromosome 11.
A patient is reported who developed dysplastic naevi at an early age. He also suffered from a syndrome including Wilms' tumour, aniridia, mental retardation and diabetes mellitus in association with an interstitial deletion of the short arm of chromosome 11. It is suggested that genetic factors may be important in sporadic as well as familial cases of the dysplastic naevus syndrome.
McDonagh
A J
AJ
Department of Dermatology, Royal Hallamshire Hospital, Sheffield, UK.
Wright
A L
AL
Messenger
A G
AG
D000328:Adult; D002872:Chromosome Deletion; D002880:Chromosomes, Human, Pair 11; D004416:Dysplastic Nevus Syndrome / Q000235:genetics* / Q000473:pathology; D006801:Humans; D008297:Male; D012867:Skin / Q000473:pathology