Fetal brain disruption sequence: a milder variant.
We report on a female infant with severe microcephaly, scalp rugae, overlapping sutures, and telancephalic damage with relatively satisfactory early motor development. This case represents a milder form of the 'fetal brain disruption sequence', which is thought to be the result of an exogenous insult to the developing brain during the second half of gestation.
Bönnemann
C G
CG
Altonaer Kinderkrankenhaus, Hamburg, Federal Republic of Germany.
Meinecke
P
P
D005147:Facial Bones / Q000002:abnormalities*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008831:Microcephaly / Q000175:diagnosis* / Q000000981:diagnostic imaging; D011859:Radiography; D012535:Scalp / Q000002:abnormalities*; D012886:Skull / Q000002:abnormalities*; D014054:Tomography