[The use of hyperbaric oxygenation in treating viral hepatitis B and the reaction of the blood leukocytes].
A total of 75 patients with virus hepatitis B of medium gravity were examined for the effect of HBO on the clinical course of the disease and blood leukocyte reaction. This reaction was tested on the basis of a complex of rosette-forming and cytochemical tests. HBO was found to produce a favourable effect if used at the early stages of the treatment (the first week of hospitalization). The effect consisted in significant reduction of the rate of exacerbations and residual phenomena. HBO provoked a decrease in the content of T and B lymphocytes by the 10th session of the treatment. A close relationship was revealed between HBO efficacy and the initial level of functional metabolic activity of leukocytes. The use of HBO was always accompanied by the rise of that activity during the treatment. The use of HBO at later times of the treatment (weeks 4-5) did not produce any well-defined clinical effect. Thus, HBO (8-10 sessions, pressure 1.5 absolute atmosphere, exposure 45 min) may be indicated as a prophylactic measure in respect of an unfavourable disease course with regard to the patients' selection on the basis of a complex of cytochemical tests.
Gabrilovich
D I
DI
Musarov
A L
AL
Zmyzgova
A V
AV
Shalygina
N B
NB
D000293:Adolescent; D000328:Adult; D003131:Combined Modality Therapy; D005069:Evaluation Studies as Topic; D005260:Female; D006509:Hepatitis B / Q000097:blood / Q000628:therapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D007958:Leukocyte Count; D007962:Leukocytes / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000502:physiology; D012397:Rosette Formation
Primenenie giperbaricheskoĭ oksigenatsii v lechenii virusnogo gepatita B i reaktsiia leĭkotsitov krovi.