Determination of N-acetylaspartic acid in human cerebrospinal fluid by gas chromatography-mass spectrometry.
N-Acetyl-L-aspartic acid was identified and determined in human cerebrospinal fluid. The concentration in lumbar fluid was about 2 nmol/ml and about 20 nmol/ml in ventricular fluid. There was no difference between healthy subjects and schizophrenic patients.
Swahn
C G
CG
Department of Psychiatry and Psychology, Karolinska Institutet, Stockholm, Sweden.
D000328:Adult; D001224:Aspartic Acid / Q000031:analogs & derivatives* / Q000134:cerebrospinal fluid; D002849:Chromatography, Gas; D004952:Esters / Q000134:cerebrospinal fluid; D005260:Female; D006801:Humans; D008297:Male; D013058:Mass Spectrometry; D008875:Middle Aged; D009994:Osmolar Concentration; D012016:Reference Values; D012559:Schizophrenia / Q000134:cerebrospinal fluid; D013345:Subarachnoid Hemorrhage / Q000134:cerebrospinal fluid
D004952:Esters; D001224:Aspartic Acid; C000179:N-acetylaspartate