title: [The mechanisms of a decreased tolerance for graduated physical loading in young patients suffering from diabetes mellitus].
abstract: A study of graded exercise tolerance (GET), indices of central hemodynamics and energy metabolism in 136 patients with insulin-dependent diabetes mellitus and 35 controls aged 16 to 40 has shown reduced GET in 86% of the patients. It was combined with a decrease in the CVS functional potentialities and disorder of energy formation. The lowest level of GET was noted in patients with a severe type of diabetes mellitus in marked decompensation, with disease of 10 yrs. of duration at advanced stages of diabetic microangiopathies. The use of inosine and AMP is accompanied by a rise of GET and the activity of energy producing systems.
authors.forename: M N
authors.initials: MN
authors.lastname: Solun
authors.forename: A I
authors.initials: AI
authors.lastname: Kalashnikova
authors.forename: A N
authors.initials: AN
authors.lastname: Goch
mesh_terms: D000293:Adolescent; D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000503:physiopathology*; D004734:Energy Metabolism / Q000502:physiology; D004912:Erythrocytes / Q000378:metabolism; D005080:Exercise Test; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D010807:Physical Endurance / Q000502:physiology*; D005082:Physical Exertion / Q000502:physiology*; D013997:Time Factors
vernacular_title: O mekhanizmakh snizheniia tolerantnosti k dozirovannoĭ fizicheskoĭ nagruzke u bol'nykh molodovogo vozrasta, stradaiushchikh sakharnym diabetom.