title: [Multifocal carcinoma of the upper female genital tract: diffuse Müllerian neoplasia].
abstract: The simultaneous occurrence of moderately differentiated mesonephroid adenocarcinomas of the endocervix and the ovary and a well differentiated adenocarcinoma of the endometrium in a 46-year-old woman are reported. The problems of classification as multiple primary neoplasma or as metastatic spread are discussed. Histogenesis of multiple primary epithelial malignancies of the female genital tract is explained by the theory of area response of embryologically related organs to an unknown carcinogenic stimulus.
authors.affiliation: Frauenklinik, Universität Köln.
authors.forename: A
authors.initials: A
authors.lastname: Scharl
authors.forename: M
authors.initials: M
authors.lastname: Günther
authors.forename: U J
authors.initials: UJ
authors.lastname: Göhring
authors.forename: A
authors.initials: A
authors.lastname: Bolte
authors.forename: R
authors.initials: R
authors.lastname: Fischer
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D002584:Cervix Uteri / Q000473:pathology; D004717:Endometrium / Q000473:pathology; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008649:Mesonephroma / Q000473:pathology*; D008875:Middle Aged; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000473:pathology*; D010053:Ovary / Q000473:pathology; D002583:Uterine Cervical Neoplasms / Q000473:pathology*; D014594:Uterine Neoplasms / Q000473:pathology*
vernacular_title: Multifokale Karzinome des oberen weiblichen Genitaltrakts: Diffuse Müllersche Neoplasie.