title: Radiation-induced esophageal cancer: a case report and a review of the literature.
abstract: A 63 year old woman who had been irradiated for thyroid carcinoma at 36 years of age developed a cervico-esophageal stricture, the biopsy specimens from which revealed squamous cell carcinoma. Total esophagectomy was performed and a small linear ulcer was found in the resected specimen. Histological examination revealed moderately differentiated squamous cell carcinoma with severe fibrosis around the tumor, indicating radiation-induced cervical esophageal cancer. The characteristics of radiation-induced esophageal cancers described in the literature are reviewed in context of the present case.
authors.affiliation: First Department of Surgery, Tottori University School of Medicine, Yonago, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Shimizu
authors.forename: T
authors.initials: T
authors.lastname: Matsui
authors.forename: O
authors.initials: O
authors.lastname: Kimura
authors.forename: M
authors.initials: M
authors.lastname: Maeta
authors.forename: S
authors.initials: S
authors.lastname: Koga
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology; D004938:Esophageal Neoplasms / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000473:pathology*