[The use of finoptin and alpha-tocopherol in patients with stable exertional stenocardia].
A study of 59 patients of stable exertion stenocardia (functional class III) revealed an increased content of lipid hydroperoxide in lipoproteids of low and very low density that was associated with an increased level of malonic dialdehyde in of their functional activity, in particular, during physical loads. Finoptin monotherapy did not effect essentially the level of hydroperoxides in lipoproteids of low density, malonic dialdehyde in thrombocytes. Combination of finoptin and alpha-tocopherol reduced essentially the processes of lipid peroxidation, reducing, thus, the functional activity of thrombocytes at rest and loads.
Levchenko
V A
VA
Serediuk
N N
NN
Gereliuk
I P
IP
Vakaliuk
I P
IP
Bondar'
M M
MM
D000328:Adult; D000787:Angina Pectoris / Q000097:blood / Q000188:drug therapy*; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D008875:Middle Aged; D010807:Physical Endurance / Q000187:drug effects; D005082:Physical Exertion; D010974:Platelet Aggregation / Q000187:drug effects; D014700:Verapamil / Q000627:therapeutic use*; D014810:Vitamin E / Q000627:therapeutic use*
D014810:Vitamin E; D014700:Verapamil
Primenenie finoptina i al'fa-tokoferola ubol'nykh stabil'noĭ stenokardieĭ napriazheniia.