Suspected familial renal disease in chow chows.
Renal disease was diagnosed in 6 young Chow Chows. Clinical abnormalities included vomiting, polyuria, polydipsia, and weight loss. Common abnormal laboratory findings were azotemia, hyperphosphatemia, hypocalcemia, nonregenerative anemia, and low urine specific gravity. All 6 dogs had similar microscopic renal lesions. characterized by interstitial fibrosis, a population of small glomeruli, and lack of inflammatory cells. A familial basis for the renal disease is suggested because of its development in 4 closely related dogs.
Brown
C A
CA
Department of Veterinary Pathology, College of Veterinary Medicine, University of Georgia, Athens 30602.
Crowell
W A
WA
Brown
S A
SA
Barsanti
J A
JA
Finco
D R
DR
D000818:Animals; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D005260:Female; D007668:Kidney / Q000473:pathology; D007674:Kidney Diseases / Q000235:genetics / Q000662:veterinary*; D007676:Kidney Failure, Chronic / Q000235:genetics / Q000662:veterinary*; D008297:Male; D010375:Pedigree