title: Genetic evidence that the gene controlling Aub is located on chromosome 19.
abstract: DNA from a series of families segregating for Aub was analyzed with a genomic DNA probe which defines a Bg1 I polymorphism for apolipoprotein C II (APOC2). The investigation revealed that the gene for Aub is closely linked to APOC2 (z = 8.43 at theta = 0.00) for paternal and maternal meioses combined, to LW (z = 3.61 at theta = 0.00) in paternal meioses and less closely linked to SE (z = 3.10 at theta = 0.09) for combined paternal and maternal meioses. Therefore, we propose a chromosome 19 location for the Aub gene.
authors.affiliation: Department of Pediatrics, University of Manitoba, Canada.
authors.forename: T
authors.initials: T
authors.lastname: Zelinski
authors.forename: H
authors.initials: H
authors.lastname: Kaita
authors.forename: K
authors.initials: K
authors.lastname: Johnson
authors.forename: M
authors.initials: M
authors.lastname: Moulds
mesh_terms: D001789:Blood Group Antigens / Q000235:genetics*; D002874:Chromosome Mapping; D002888:Chromosomes, Human, Pair 19; D008040:Genetic Linkage; D006801:Humans
chemical_list: D001789:Blood Group Antigens