[Properties of adenylate cyclase system in heart muscle and aorta of rats with experimental renal hypertension].
Properties of the adenylate cyclase system were simultaneously studied in heart and aorta of rats with renovascular hypertension. Under conditions of the pathology molecular interactions between adrenoreceptors, regulating proteins (N-proteins) and catalytic subunit of the adenylate cyclase system were deteriorated in rat myocardium as well as functions of the regulating component were impaired in the adenylate cyclase system of aorta smooth muscles.
Soltitskaia
L P
LP
Balashov
N V
NV
Soltitskiĭ
V V
VV
D000067956:Adenylyl Cyclase Inhibitors; D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D001011:Aorta / Q000201:enzymology*; D004789:Enzyme Activation; D006160:Guanosine Triphosphate / Q000494:pharmacology; D006977:Hypertension, Renal / Q000201:enzymology*; D007545:Isoproterenol / Q000494:pharmacology; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains; D012969:Sodium Fluoride / Q000494:pharmacology
D000067956:Adenylyl Cyclase Inhibitors; D006160:Guanosine Triphosphate; D012969:Sodium Fluoride; D000262:Adenylyl Cyclases; D007545:Isoproterenol
Svoĭstva adenilattsiklaznoĭ sistemy myshts serdtsa i aorty u krys s éksperimental'noĭ pochechnoĭ gipertonieĭ.