[Carboxylic acid anhydrides as a cause for occupational allergic respiratory tract diseases in the handling of epoxy resins].
Low molecular weight chemicals like anhydrides of dicarboxylic acids, capable of reaction with human serum proteins and of formation of hapten-carrier conjugates, can produce pathogenic immunoreactions. It was proved, that the observed diseases can also be of allergic genesis after the exposure to these noxae of the respiratory tract with mainly irritating effect.
Schöneich
R
R
Zentralinstitut für Arbeitsmedizin, DDR.
Wallenstein
G
G
D000812:Anhydrides / Q000009:adverse effects*; D003998:Dicarboxylic Acids / Q000009:adverse effects*; D004781:Environmental Exposure; D004853:Epoxy Resins / Q000009:adverse effects; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D011009:Pneumoconiosis / Q000209:etiology*; D011852:Radioallergosorbent Test; D011863:Radioimmunoassay; D012130:Respiratory Hypersensitivity / Q000175:diagnosis / Q000209:etiology*
D000812:Anhydrides; D003998:Dicarboxylic Acids; D004853:Epoxy Resins; D007073:Immunoglobulin E
Carbonsäureanhydride als Ursache arbeitsbedingter allergischer Atemwegserkrankungen beim Umgang mit Epoxidharz.