[Questionable usefulness of the edrophonium test in the diagnosis of non-cardiac retrosternal pain].
Of 69 patients with non-cardiac chest pain, one third had abnormal esophageal motility as evidenced by basal esophageal manometry. 8 patients (12%) reported chest pain during a provocation test (edrophonium). While this pain seemed similar to the spontaneous chest pain described by 7 patients, it was not associated with manometric changes in 30% of these cases. The causal relationship between disorders of esophageal motility and non-cardiac chest pain has still to be confirmed, and caution must be exercised in interpreting edrophonium tests.
Apollonio
G
G
Département de médecine, Hôpital cantonal universitaire, Genève.
Dederding
J P
JP
Bosson
R
R
Baumann
R
R
Loup
R
R
Girard
L
L
Miazza
B
B
de Peyer
R
R
Loizeau
E
E
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002637:Chest Pain / Q000175:diagnosis* / Q000209:etiology; D004491:Edrophonium; D015154:Esophageal Motility Disorders / Q000150:complications / Q000175:diagnosis*; D005189:False Positive Reactions; D005260:Female; D005769:Gastrointestinal Motility / Q000187:drug effects; D006801:Humans; D008297:Male; D008365:Manometry / Q000379:methods; D008875:Middle Aged
D004491:Edrophonium
Utilité discutable du test à l'édrophonium dans le diagnostic d'une douleur rétrosternale non cardiaque.