Sandimmun metabolites: their potential to cause adverse reactions in the rat.
Donatsch
P
P
Department of Drug Safety Assessment, Sandoz, Basel, Switzerland.
Rickenbacher
U
U
Ryffel
B
B
Brouillard
J F
JF
D000818:Animals; D003524:Cyclosporins / Q000493:pharmacokinetics / Q000633:toxicity*; D007166:Immunosuppressive Agents / Q000493:pharmacokinetics / Q000633:toxicity*; D007668:Kidney / Q000187:drug effects*; D007677:Kidney Function Tests; D007684:Kidney Tubules / Q000187:drug effects; D008099:Liver / Q000187:drug effects*; D008111:Liver Function Tests; D051381:Rats; D011918:Rats, Inbred SHR; D013329:Structure-Activity Relationship
D003524:Cyclosporins; D007166:Immunosuppressive Agents