[Effects of tiao-zhi-tang on lipoprotein and apolipoprotein in hyperlipemic patients].
In this research, 68 patients suffering from hyperlipemia were divided into observation group taking Tiao-Zhi-Tang (TZT) and control group taking inositol and Mai Tong at random and matched-pair, and the serum levels of HDL-c, HDL2-c, LDL-c, Apo A-I and Apo B were measured respectively by the methods of polyethylene glycol precipitation separation and single radial immunodiffusion. The results showed that there were significant difference in the levels of lipoprotein, apolipoprotein between the patient groups and the healthy group before taking medicines. After taking medicines for four weeks, the serum levels of total cholesterol, triglyceride (TG), LDL-c and Apo B were lowered and the serum levels of HDL-c, HDL2-c and Apo A-I were elevated in the observation group. The serum level of TG was lowered and the serum levels of HDL2-c, Apo A-I were elevated in the control group. The effects of TZT, with the serum levels of LDL-c and Apo B being lowered and the serum level of HDL-c being elevated, were more beneficial than inositol and Mai Tong. These results suggested that TZT had a good effect on regulating the lipoprotein metabolism.
Jia
B
B
Hospital Attached to Heilongjiang College of TCM, Harbin.
Bao
L
L
D000328:Adult; D001055:Apolipoproteins B / Q000097:blood*; D002784:Cholesterol / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood
D001055:Apolipoproteins B; D008078:Cholesterol, LDL; D004365:Drugs, Chinese Herbal; D014280:Triglycerides; D002784:Cholesterol