title: High-speed separations of DNA sequencing reactions by capillary electrophoresis.
abstract: Fluorescently labeled DNA fragments generated in enzymatic sequencing reactions are rapidly separated by capillary gel electrophoresis and detected at attomole levels within the gel-filled capillary. The application of this technology to automated DNA sequence analysis may permit the development of a second generation automated sequencer capable of efficient and cost-effective sequence analysis on the genomic scale.
authors.affiliation: Department of Chemistry, University of Wisconsin, Madison 53706.
authors.forename: H
authors.initials: H
authors.lastname: Drossman
authors.forename: J A
authors.initials: JA
authors.lastname: Luckey
authors.forename: A J
authors.initials: AJ
authors.lastname: Kostichka
authors.forename: J
authors.initials: J
authors.lastname: D'Cunha
authors.forename: L M
authors.initials: LM
authors.lastname: Smith
mesh_terms: D001483:Base Sequence; D004247:DNA / Q000032:analysis*; D004586:Electrophoresis; D008969:Molecular Sequence Data; D013050:Spectrometry, Fluorescence
chemical_list: D004247:DNA