title: [Multiple sclerosis with early manifestation in children].
abstract: From the starting point of cases reported in literature, five of the authors' own cases are reported in which multiple sclerosis had its origins not later than in the fourteenth year of the patient's life. There is no basic difference from adult cases in respect of neurological symptoms, course, and cerebrospinal-fluid condition, but unmistakably, well remitting episodic courses were in the foreground, multilocular failures preponderated, and cerebral symptoms predominated over spinal symptoms. As in adult cases, females were more commonly affected. There were inflammatory changes in the cerebrospinal fluid.
authors.affiliation: Klinik für Psychiatrie und Neurologie, Medizinischen Akademie Carl Gustav Carus, Dresden.
authors.forename: J
authors.initials: J
authors.lastname: Müller
authors.forename: H
authors.initials: H
authors.lastname: Todt
authors.forename: W
authors.initials: W
authors.lastname: Sauermann
mesh_terms: D000293:Adolescent; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000188:drug therapy; D009460:Neurologic Examination; D009896:Optic Atrophy / Q000175:diagnosis; D009902:Optic Neuritis / Q000175:diagnosis; D011241:Prednisone / Q000627:therapeutic use
chemical_list: D011241:Prednisone
vernacular_title: Multiple Sklerose mit Frühmanifestation im Kindesalter.