title: [Granulomatous thrombophlebitis in Lyme borreliosis--case report].
abstract: The presented case report shows a patient with Lyme disease who also developed thrombophlebitis saltans. Histopathologically we found a granulomatous perivasculitis, an immunohistological investigation showed deposits of IgG, IgA, IgM, C3 and C4 in the vessels. Antibody titers against Borrelia burgdorferi were elevated, but no anti-cardiolipin antibodies were found. A pathogenetic correlation due to anti-phospholipid antibodies that have been found in thrombosis and borreliosis or a vasculitis vasorum comparable to a previously described vasculitis nervorum might be discussed.
authors.affiliation: Krankenhaus Müchen-Bogenhausen IV. Medizinische Abetilung/Rheumatologie und Klinische Immunologie.
authors.forename: M
authors.initials: M
authors.lastname: Lauer
authors.forename: K
authors.initials: K
authors.lastname: Stölze
authors.forename: H J
authors.initials: HJ
authors.lastname: Hatz
authors.forename: K
authors.initials: K
authors.lastname: Helmke
authors.forename: W
authors.initials: W
authors.lastname: Löffler
mesh_terms: D000907:Antibodies, Bacterial / Q000032:analysis; D015748:Borrelia burgdorferi Group / Q000276:immunology; D003176:Complement C3 / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D006099:Granuloma / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007150:Immunohistochemistry; D008193:Lyme Disease / Q000150:complications*; D008297:Male; D013924:Thrombophlebitis / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D014465:Ultrasonics
chemical_list: D000907:Antibodies, Bacterial; D003176:Complement C3; D003181:Complement C4; D007136:Immunoglobulins
vernacular_title: Granulomatöse Thrombophlebitis bei Lyme-Borreliose--Fallvorstellung.