Stimulation of sexual performance in male rats with the root extract of dinh lang (Policias fruticosum L.).
Ginseng (Panax ginseng C.A. Meyer) is probably the best known medicinal plant, the extract of which is used in the Far East as a traditional remedy. Dinh lang (Polycias fruticosum L.) root extract (DLRE) was found to have a pharmacological spectrum similar to Ginseng. Experimental and clinical studies have shown a wide range of pronounced stimulatory effects of DLRE which showed low toxicity. It increases mental and physical performance. This study is devoted to demonstrate the effect of DLRE on sexual performance of male rats. Different age-cohorts of Wistar male rats [6-8 months old (n = 204), 16-18-months old (n = 240) and 22-24 month old (n = 122)], were used for these experiments. The rats of each age cohort were divided into 4 groups. One group received saline, others were treated with various doses of DLRE daily. Treatment started 10 days before the screening test and continued during the test period. DLRE reduced the percentage of non-copulators in the aged rats compared to the younger ones. In the aged rats DLRE transformed high percentage of sluggish rats to sexually fully active animals. In sexually fully active 6-8 months old rats the percentage of rats displaying ejaculation with the second female was found to be significantly higher in DLRE-treated males. Also the recovery of the sexually exhausted male rats proved to be faster in DLRE-treated groups.
Tran Ty Yen
Department of Pharmacology, Semmelweis University Medical School, Budapest, Hungary.
D000375:Aging / Q000502:physiology; D000818:Animals; D003307:Copulation / Q000187:drug effects; D005260:Female; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D014744:Vietnam
D010936:Plant Extracts