title: Effect of lithium on the intracellular potassium concentration in sheep heart Purkinje fibres.
abstract: Simultaneous measurements were made of the intracellular activities of potassium and lithium in sheep heart Purkinje fibres using ion-sensitive microelectrodes. On exposure of the fibres to lithium, the intracellular activity of lithium rose, with an equivalent decrease in the level of intracellular potassium.
authors.affiliation: Department of Physiology, University Medical School, Edinburgh.
authors.forename: I F
authors.initials: IF
authors.lastname: Gow
authors.forename: D
authors.initials: D
authors.lastname: Ellis
mesh_terms: D000818:Animals; D003593:Cytoplasm / Q000378:metabolism; D006329:Heart Conduction System / Q000187:drug effects*; D008094:Lithium / Q000494:pharmacology*; D008839:Microelectrodes; D011188:Potassium / Q000378:metabolism*; D011690:Purkinje Fibers / Q000187:drug effects* / Q000378:metabolism; D012756:Sheep
chemical_list: D008094:Lithium; D011188:Potassium