[Post-heparin LPL and HL activities after two months' treatment with gemfibrozil. Study in 6 normolipemic volunteers].
Post-heparin lipolytic activities and lipidic parameters (cholesterol, HDL-cholesterol, triglycérides, Apo B) were studied in 6 human volunteers submitted to gemfibrozil treatment (900 mg once a day) during two months. Though lipidic parameters were not modified after treatment, gemfibrozil increased the LPL and HL plasmatic activities measured 10 minutes after heparin injection.
Millot
F
F
Service de Biochimie, Hôpital Tenon, Paris.
Etienne
J
J
Cloarec
M
M
Laruelle
P
P
D000328:Adult; D005260:Female; D015248:Gemfibrozil / Q000494:pharmacology*; D006493:Heparin / Q000008:administration & dosage / Q000494:pharmacology; D006801:Humans; D007275:Injections, Intravenous; D008049:Lipase / Q000378:metabolism*; D008071:Lipoprotein Lipase / Q000378:metabolism*; D008099:Liver / Q000201:enzymology; D008297:Male; D008875:Middle Aged
D006493:Heparin; D008049:Lipase; D008071:Lipoprotein Lipase; D015248:Gemfibrozil
Activités LPL et HL post-hépariniques après traitement de 2 mois par le gemfibrozil. Etude chez 6 volontaires normalipémiques.