[Ultrastructural manifestations of pulmonary thrombohemorrhagic syndrome in endotoxic shock].
In electron microscopic investigation in the initial period of endotoxin shock in rats, rabbits and dogs there are haemorrhages and microthrombi with precipitation of fibrin. In intermediate period of shock signs of intravascular coagulation predominate and on the stage of late endotoxemia qualitatively new sign of destruction is interstitial fibrosis. Involving of coagulative link completes and enhances microcirculatory changes in the lungs and promotes formation of acute lung insufficiency.
Bardakhch'ian
E A
EA
Kharlanova
N G
NG
D000208:Acute Disease; D000818:Animals; D004211:Disseminated Intravascular Coagulation / Q000473:pathology; D004285:Dogs; D006470:Hemorrhage / Q000473:pathology*; D008168:Lung / Q000648:ultrastructure*; D008171:Lung Diseases / Q000473:pathology*; D008833:Microcirculation; D011652:Pulmonary Circulation; D011658:Pulmonary Fibrosis / Q000473:pathology; D011817:Rabbits; D051381:Rats; D012131:Respiratory Insufficiency / Q000209:etiology; D012772:Shock, Septic / Q000473:pathology*; D013577:Syndrome; D013927:Thrombosis / Q000473:pathology*
Ul'trastrukturnye proiavleniia trombogemorragichskogo sindroma v legkikh pri éndotoksinovom shoke.