Effects of prenatal alcohol exposure on rat pups' ability to elicit retrieval behavior from dams.
Research on fetal alcohol syndrome (FAS) has historically held that postnatal deficits result directly from prenatal alcohol exposure. Such exposure may alter infant behavior, and this in turn may affect maternal responsiveness and consequently increase the infant's risk for postnatal deficits. This study examined the effect of prenatal alcohol exposure on postnatal blood ethanol concentrations, pup development, and the ability of pups to elicit retrieval behaviors from the dam. Dams given access to a 15% ethanol solution throughout gestation and lactation showed blood ethanol concentrations of 0.1%, whereas their pups had concentrations below the sensitivity of the test. Prenatal alcohol exposure was shown to have pharmacological effects on the pup's righting reflex and nutritional effects on its rate of weight gain. Control pups were better able to elicit retrieval behavior from control and alcoholic dams than were fetally alcoholic pups. These results indicate that the condition of the pup can influence maternal responsiveness which, in turn, can influence pup development.
Ness
J W
JW
Department of Psychology, Virginia Polytechnic Institute and State University, Blacksburg.
Franchina
J J
JJ
D000818:Animals; D001143:Arousal / Q000502:physiology; D000431:Ethanol / Q000493:pharmacokinetics; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000097:blood / Q000523:psychology*; D008425:Maternal Behavior; D008431:Maternal-Fetal Exchange / Q000502:physiology; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D011930:Reaction Time / Q000502:physiology; D014828:Vocalization, Animal / Q000502:physiology
D000431:Ethanol