[Acute changes in the body of laboratory rats during development after the parenteral administration of the herbicide Zeazin S-40. I. Determination of LD50 and other biochemical findings].
On laboratory rats of different age the effect of the acute intraperitoneal administration of the herbicide Zeazin S-40, 570 mg.kg-1 was investigated. The dose was derived after assessment of LD50 i. p. It was revealed that this substance causes during the first hour after introduction into the organism a response in the internal environment manifested among others by changes in the serum levels of glucose, lactate and triacylglycerols.
Trojanová
M
M
Fyziologický ústav fakulty vseobecného lékarství Univerzity Karlovy, Praha.
Mourek
J
J
D000375:Aging / Q000378:metabolism; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D005260:Female; D006540:Herbicides / Q000494:pharmacology / Q000633:toxicity*; D007274:Injections, Intraperitoneal; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D007928:Lethal Dose 50; D008297:Male; D009930:Organic Chemicals; D051381:Rats; D011919:Rats, Inbred Strains; D014280:Triglycerides / Q000097:blood
D001786:Blood Glucose; D006540:Herbicides; D007773:Lactates; D009930:Organic Chemicals; D014280:Triglycerides; D019344:Lactic Acid; C064418:Zeazin S 40
Akutní zmĕny v organismu laboratorního potkana za vývoje po parenterálním podání herbicidu Zeazin S-40. I. Stanovení LD50 a nĕkteré biochemické nálezy.