title: [Locally advanced breast cancer--primary treatment with tamoxifen].
abstract: Tamoxifen was given as primary systemic treatment to 28 patients with locally advanced breast cancer. In all tumours, receptors for estrogen (ER) and/or progesterone (PGR) were positive. All patients (15) with high levels of hormone receptors (ER greater than or equal to 100 mumols/g protein and/or PGR greater than or equal to 200 mumols/g protein) were alive after two years of observation as against 60% of the patients (13) with lower hormone receptor values.
authors.affiliation: Avdeling for medisinsk onkologi Det Norske Radiumhospital, Oslo.
authors.forename: H
authors.initials: H
authors.lastname: Melsom
authors.forename: O R
authors.initials: OR
authors.lastname: Monge
authors.forename: S D
authors.initials: SD
authors.lastname: Fosså
authors.forename: S
authors.initials: S
authors.lastname: Gundersen
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000378:metabolism; D005260:Female; D006801:Humans; D008875:Middle Aged; D013629:Tamoxifen / Q000627:therapeutic use*
chemical_list: D013629:Tamoxifen
vernacular_title: Lokalavansert brystkreft--primaerbehandling med tamoxifen.