[Molecular mechanisms of radiation-induced cell death].
Current data on the molecular mechanisms responsible for radiation-induced interphase death of lymphoid cells are presented. This radiobiological phenomenon is considered to be a special case of the general biological event of programmed cell death. Ionizing radiation and factors inducing terminal differentiation and programmed cell death are shown to activate some specific genes, whose products are needed for further steps of cellular self-destruction.
Khanson
K P
KP
Zhivotovskiĭ
B D
BD
D000818:Animals; D002454:Cell Differentiation / Q000502:physiology / Q000528:radiation effects; D002470:Cell Survival / Q000528:radiation effects*; D004249:DNA Damage; D006801:Humans; D007399:Interphase / Q000502:physiology / Q000528:radiation effects; D008938:Mitosis / Q000502:physiology / Q000528:radiation effects*; D011832:Radiation Injuries / Q000235:genetics / Q000473:pathology*; D011836:Radiation Tolerance; D051381:Rats; D013601:T-Lymphocytes / Q000473:pathology / Q000528:radiation effects* / Q000648:ultrastructure; D013950:Thymus Gland / Q000473:pathology / Q000528:radiation effects*
Molekuliarnye mekhanizmy radiatsionnoĭ gibeli kletok.