title: Churg-Strauss vasculitis and ascaris infection.
abstract: A patient with Churg-Strauss vasculitis presenting with mononeuritis multiplex, who developed obstructive jaundice, is described. On investigation the jaundice proved to be due to ascaris infestation. As the immune abnormalities associated with ascaris infection are also typical of those seen in the Churg-Strauss syndrome it is speculated that the vasculitis occurred because of a failure to regulate the anti-ascaris immune response.
authors.affiliation: Department of Rheumatology, University of Birmingham, UK.
authors.forename: A
authors.initials: A
authors.lastname: Chauhan
authors.forename: D G
authors.initials: DG
authors.lastname: Scott
authors.forename: J
authors.initials: J
authors.lastname: Neuberger
authors.forename: J S
authors.initials: JS
authors.lastname: Gaston
authors.forename: P A
authors.initials: PA
authors.lastname: Bacon
mesh_terms: D000936:Antigen-Antibody Complex / Q000032:analysis; D001196:Ascariasis / Q000150:complications* / Q000276:immunology; D002779:Cholestasis / Q000209:etiology* / Q000276:immunology; D015267:Churg-Strauss Syndrome / Q000150:complications* / Q000276:immunology; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D008297:Male; D008875:Middle Aged
chemical_list: D000936:Antigen-Antibody Complex; D007070:Immunoglobulin A