Recurrence and malignant transformation of endotracheal chondroma.
An endotracheal chondroma with recurrent course and malignant transformation is described. The first chondroma recurrence appeared 5 years after the primary operation, with no histopathological signs of malignancy. A second recurrence after a further 6 years showed obvious histological evidence of malignant chondrosarcoma. A third recurrence after 1 more year metastasized to various organs and led to the patient's death 14 years from the date of primary diagnosis.
Salminen
U S
US
Department of Thoracic and Cardiovascular Surgery, Helsinki University Central Hospital, Finland.
Halttunen
P
P
Taskinen
E
E
Mattila
S
S
D001932:Brain Neoplasms / Q000556:secondary; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D002812:Chondroma / Q000473:pathology* / Q000601:surgery; D002813:Chondrosarcoma / Q000473:pathology* / Q000556:secondary; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery; D013899:Thoracic Neoplasms / Q000556:secondary; D014134:Tracheal Neoplasms / Q000473:pathology* / Q000601:surgery