The human genome: the nature of the enterprise.
The development of methods of cloning and sequencing DNA has liberated genetics from the constraints of breeding experiments, and all organisms are now accessible to genetical analysis by the new methods. The analysis of the human genome is likely to produce a revolution in biomedical science, and it is argued that high priority should be given to gene identification. The strategy advocated is one which identifies the expressed genes and pursues mapping in parallel.
Brenner
S
S
MRC Molecular Genetics Unit, Cambridge, UK.
D015894:Genome, Human; D015698:Genomic Library; D006801:Humans; D009710:Nucleotide Mapping