title: [Acute hemodynamic effects of adriamycin].
abstract: Several authors reported about acute haemodynamic effects of ADM years ago. We studied this problem in five patients in the invasive and noninvasive way and thus obtained the most important haemodynamic parameters. Acute haemodynamic effects in the meaning of a negative inotropy and vasodilatation are confirmed. The usual intravenous injection does not avoid the decrease of important haemodynamic parameters (SV, SWI, CI) even though injected over ten minutes. Possible infarction and complications during the injection may be the result of decrease of perfusion pressure in the meaning of a "steal phenomenon".
authors.affiliation: Klinik für Innere Medizin des Bezirkskrankenhauses Stralsund.
authors.forename: U
authors.initials: U
authors.lastname: Gerecke
authors.forename: B
authors.initials: B
authors.lastname: Katzberg
mesh_terms: D003864:Depression, Chemical; D004317:Doxorubicin / Q000008:administration & dosage / Q000494:pharmacology*; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D007275:Injections, Intravenous; D009200:Myocardial Contraction / Q000187:drug effects; D013318:Stroke Volume / Q000187:drug effects
chemical_list: D004317:Doxorubicin
vernacular_title: Hämodynamische Akutwirkungen von Adriamycin.