title: CGRP-like immunoreactivity in sensory nerve endings of the Golgi tendon organ. A light- and electron-microscopic study in the grey short-tailed opossum (Monodelphis domestica).
abstract: Using light- and electron-microscopic immunohistochemistry, it was shown that primary sensory nerve endings in Golgi tendon organs of the grey short-tailed opossum (Monodelphis domestica) contain immunoreactivities to a polyclonal antibody directed against calcitonin gene-related peptide (CGRP). Myelinated afferent axons (6-9 microns in diameter) of the Golgi tendon organs stained moderately for CGRP. Sensory nerve endings within the sensory compartment of the Golgi tendon organs displayed electron-dense accumulations corresponding to dark-brown staining in adjacent semithin sections. On the outer surface of tendon organs C fibre bundles were observed showing CGRP-like immunoreactivity.
authors.affiliation: Institute of Anatomy, University of Hamburg, FRG.
authors.forename: T
authors.initials: T
authors.lastname: Strasmann
authors.forename: E
authors.initials: E
authors.lastname: Weihe
authors.forename: Z
authors.initials: Z
authors.lastname: Halata
mesh_terms: D000818:Animals; D015740:Calcitonin Gene-Related Peptide / Q000276:immunology*; D005260:Female; D007150:Immunohistochemistry / Q000379:methods; D008854:Microscopy, Electron / Q000379:methods; D009475:Neurons, Afferent / Q000166:cytology / Q000276:immunology* / Q000648:ultrastructure; D009893:Opossums / Q000033:anatomy & histology*; D012679:Sense Organs / Q000166:cytology / Q000276:immunology* / Q000648:ultrastructure
chemical_list: D015740:Calcitonin Gene-Related Peptide