Hysteroscopic follow-up during tamoxifen treatment.
In order to study the action of Tamoxifen upon the uterus, 16 breast cancer patients were prospectively evaluated by means of an hysteroscopy before Tamoxifen therapy and again after 6 to 36 months of treatment. The results show the occurrence of an endometrial polyp in four cases and of an adenocarcinoma in one case. Moreover, the previously atrophic mucosa became mildly proliferative in seven of the patients who were evaluated.
Neven
P
P
Department of Obstetrics and Gynaecology, Clinique Générale Saint-Jean, Bruxelles, Belgium.
De Muylder
X
X
Van Belle
Y
Y
Vanderick
G
G
De Muylder
E
E
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000188:drug therapy; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D008875:Middle Aged; D011446:Prospective Studies; D013629:Tamoxifen / Q000009:adverse effects*; D014591:Uterine Diseases / Q000139:chemically induced; D014599:Uterus / Q000187:drug effects*
D013629:Tamoxifen