title: Effects of melatonin on gonadal steroids and glucose plasma levels in frogs (Rana perezi and Rana temporaria).
abstract: The effect of melatonin treatment on the Gonosomatic Index (GSI), ovarian germinal epithelium, plasma estradiol and testosterone levels was studied in Rana perezi females in December. No significant changes were observed in GSI, estradiol, and testosterone levels in melatonin treated animals when compared with saline injected controls, but the percentage of previtellogenic follicles decreased in animals treated with melatonin (100 micrograms). The effect of melatonin treatment on glucose level was studied in Rana perezi females in December and Rana temporaria males in February. In Rana perezi no significant differences were observed between melatonin treated and control animals; however, significant reductions by melatonin treatment were obtained in Rana temporaria. The possibility that the inhibitory effect of melatonin can be observed only when gonadal function and metabolism are stimulated by temperature is discussed.
authors.affiliation: Departamento de Fisiologia Animal, Facultad de Biologia, Universidad Complutense de Madrid, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Alonso-Bedate
authors.forename: R
authors.initials: R
authors.lastname: Carballada
authors.forename: M J
authors.initials: MJ
authors.lastname: Delgado
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000032:analysis*; D004958:Estradiol / Q000097:blood*; D005260:Female; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D009929:Organ Size / Q000187:drug effects; D010053:Ovary / Q000033:anatomy & histology / Q000187:drug effects; D011896:Rana temporaria / Q000502:physiology*; D011898:Ranidae / Q000502:physiology*; D013739:Testosterone / Q000097:blood*
chemical_list: D001786:Blood Glucose; D013739:Testosterone; D004958:Estradiol; D008550:Melatonin