Characteristics of a cell line established from a Chinese patient with a squamous carcinoma of the uterine cervix.
A new cell line, CC3/CUHK3, was established from a squamous carcinoma of the uterine cervix from a Chinese patient. Light microscopy of the cell line revealed keratin and electron microscopy demonstrated tonofilaments and desmosomes, thereby confirming its epithelial nature. The population doubling time of CC3/CUHK3, estimated from the exponential growth phase of the growth curve established from the cell line was 42 hours. When the tumour cells were inoculated into athymic mouse, a tumour, microscopically diagnosed as a well-differentiated carcinoma, developed. These cells are highly invasive in vitro.
Chew
E C
EC
Department of Anatomy, Faculty of Medicine, The Chinese University of Hong Kong.
Ho
T H
TH
Yeung
S O
SO
Hou
H J
HJ
Li
R S
RS
Huang
D P
DP
Wong
F W
FW
D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000235:genetics / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D051379:Mice; D014407:Tumor Cells, Cultured; D002583:Uterine Cervical Neoplasms / Q000235:genetics / Q000473:pathology* / Q000648:ultrastructure