[The interrelationship between the electronic structure and the radioprotective activity of indolylalkylamines].
Using MNDO and geometry optimization the ground state of indolylalkylamine molecules' monocationic form was calculated. Statistical relationship was established between charge distribution near atom in the fifth position and radioprotective activity of indolylalkylamines.
Sokolov
Iu A
IuA
Golubovich
V P
VP
Gurskiĭ
S G
SG
D000577:Amides / Q000494:pharmacology*; D004583:Electrons; D066298:In Vitro Techniques; D007211:Indoles / Q000494:pharmacology*; D011837:Radiation-Protective Agents; D012044:Regression Analysis; D013329:Structure-Activity Relationship
D000577:Amides; D007211:Indoles; D011837:Radiation-Protective Agents
Vzaimosviaz' mezhdu élektronnoĭ strukturoĭ i radiozashchitnoĭ aktivnnost'iu indolilalkilaminov.