title: A comparison of SCE test in human lymphocytes and Vicia faba: a hopeful technique using plants to detect mutagens and carcinogens.
abstract: A comparison of the Vicia faba SCE with the human lymphocyte SCE test was made with regard to their capacity to detect mutagens. Twelve chemical agents that can induce sister-chromatid exchanges (SCEs) in both Vicia faba root tip cells and human lymphocytes were used. The results indicate that the plant SCE technique is a sensitive test for screening various chemical agents including food preservatives, pesticides and essences which may have mutagenic activity. A new simplified procedure was introduced for differential staining of sister chromatids in Vicia faba.
authors.affiliation: Department of Biology, Nankai University, Tianjin, China.
authors.forename: W J
authors.initials: WJ
authors.lastname: Xing
authors.forename: Z L
authors.initials: ZL
authors.lastname: Zhang
mesh_terms: D015197:Carcinogenicity Tests / Q000379:methods; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure*; D009152:Mutagenicity Tests / Q000379:methods*; D010944:Plants / Q000235:genetics*; D012854:Sister Chromatid Exchange