title: Spectral editing of tumor 13C MRS in situ.
abstract: The editing pulse sequence DEPT (D.T. Pegg, D.M. Doddrell, and M.R. Bendall, J. Chem. Phys. 77, 2745 (1982)) was modified using a scheme of various composite pulses and a 16-step phase cycling to obtain proton-decoupled natural-abundance 13C edited subspectra of solid tumors. A solenoidal probe including a Faraday shield and an orthogonal saddle decoupling coil was built for this purpose.
authors.affiliation: MR Research Center, Division of Radiology, Cleveland Clinic Foundation, Ohio 44106.
authors.forename: M
authors.initials: M
authors.lastname: Xue
authors.forename: T C
authors.initials: TC
authors.lastname: Ng
authors.forename: A
authors.initials: A
authors.lastname: Majors
mesh_terms: D000818:Animals; D002247:Carbon Isotopes; D002460:Cell Line; D005260:Female; D005354:Fibrosarcoma / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D051379:Mice; D008809:Mice, Inbred C3H; D009368:Neoplasm Transplantation
chemical_list: D002247:Carbon Isotopes