title: A low flow open circle system for anaesthesia. Part I: Laboratory evaluation at normal and high frequencies.
abstract: A circle breathing system was connected by deadspace tubing to an open system valveless ventilator. The minimum volume of this tubing, required to prevent dilution of anaesthetic gas in the breathing system by the driving gas of the ventilator, was determined at frequencies of 15, 30, 60, 100 and 150 breaths/minute, with tidal volumes that ranged from 100 to 1100 ml and a fresh gas supply to the circle system of 1, 2 and 4 litres/minute. At 15 breaths/minute, tidal volumes equal to or less than the deadspace volume could be used safely without any mixing with the ventilator driving gas, when a fresh gas flow of 2 litres/minute or above is supplied to the circle system. At 1 litre/minute of fresh gas flow, mixing occurred at tidal volumes less than the deadspace volume. Mixing of gas occurred in the system at frequencies greater than 30 breaths/minute even when the tidal volume was much less than the deadspace volume. However, at high frequencies of ventilation, since the tidal volume requirement decreases, deadspace tubing with a safe internal volume, that is greater than 600 ml, may be used up to 100 breaths/minute.
authors.affiliation: Department of Anaesthetics, Royal Postgraduate Medical School, Hammersmith Hospital, London.
authors.forename: M K
authors.initials: MK
authors.lastname: Chakrabarti
authors.forename: R G
authors.initials: RG
authors.lastname: Stacey
authors.forename: A
authors.initials: A
authors.lastname: Holdcroft
authors.forename: J G
authors.initials: JG
authors.lastname: Whitwam
mesh_terms: D000764:Anesthesia, Closed-Circuit / Q000295:instrumentation; D000769:Anesthesia, Inhalation / Q000295:instrumentation*; D005069:Evaluation Studies as Topic; D006801:Humans; D009609:Nitrous Oxide / Q000008:administration & dosage; D010100:Oxygen / Q000008:administration & dosage; D013990:Tidal Volume; D012122:Ventilators, Mechanical
chemical_list: D009609:Nitrous Oxide; D010100:Oxygen