title: Blood histamine levels in HIV-1-infected infants and children.
abstract: Blood histamine levels (BHL; ng histamine base/ml blood, mean +/- SEM) were determined in 118 infants born to HIV-1-infected mothers and in children infected after blood transfusion. In asymptomatic infected infants, BHL were not significantly different from HIV-1-negative infants born to HIV-infected mothers (54.1 +/- 5.6 vs. 56.4 +/- 3.5). BHL progressively decreased in the group with polyadenopathies (40.0 +/- 4.0), in the group with AIDS-related complex (28.8 +/- 2.9), and in patients with AIDS (20.4 +/- 0.9). The decrease in BHL was associated with a decrease in blood basophil number.
authors.affiliation: INSERM U200, Laboratoire de Médecine Expérimentale et Immunologie, Faculté Necker-Enfants-Malades, Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Burtin
authors.forename: S
authors.initials: S
authors.lastname: Blanche
authors.forename: L
authors.initials: L
authors.lastname: Galoppin
authors.forename: R
authors.initials: R
authors.lastname: Merval
authors.forename: C
authors.initials: C
authors.lastname: Griscelli
authors.forename: P
authors.initials: P
authors.lastname: Scheinmann
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D015658:HIV Infections / Q000097:blood*; D015497:HIV-1; D006632:Histamine / Q000097:blood*; D006801:Humans; D007223:Infant; D007958:Leukocyte Count; D008297:Male
chemical_list: D006632:Histamine