Administration of egg-derived vaccines in patients with history of egg sensitivity.
A history of a prior hypersensitivity reaction to egg has precluded patients from receiving egg-derived vaccines. We present three cases of successful administration of egg-derived vaccines; specifically influenza and measles, mumps, and rubella (MMR) to patients with egg hypersensitivity. Two were given influenza vaccine without incident and one was successfully desensitized to MMR. Skin testing and desensitization protocols are described. Desensitization to all three components of MMR has not been reported previously.
Kletz
M R
MR
Department of Medicine, UMDNJ-New Jersey Medical School, Newark 07103-2714.
Holland
C L
CL
Mendelson
J S
JS
Bielory
L
L
D000328:Adult; D003888:Desensitization, Immunologic; D004338:Drug Combinations; D004527:Egg Proteins / Q000276:immunology*; D005260:Female; D005512:Food Hypersensitivity / Q000276:immunology*; D006801:Humans; D007223:Infant; D007252:Influenza Vaccines / Q000276:immunology*; D007428:Intradermal Tests; D008297:Male; D008458:Measles Vaccine; D022542:Measles-Mumps-Rubella Vaccine; D008875:Middle Aged; D009108:Mumps Vaccine; D011852:Radioallergosorbent Test; D012411:Rubella Vaccine
D004338:Drug Combinations; D004527:Egg Proteins; D007252:Influenza Vaccines; D008458:Measles Vaccine; D022542:Measles-Mumps-Rubella Vaccine; D009108:Mumps Vaccine; D012411:Rubella Vaccine