Subacute necrotizing lymphadenitis.
We report the skin manifestations and abnormalities of subacute necrotizing lymphadenitis. As far as we are aware, this is the first report of this disease in the dermatology literature. The main features of subacute necrotizing lymphadenitis are fever, a cervical lymphadenopathy, and, occasionally, a skin eruption resembling urticaria, rubella, or a drug-induced erythema. A skin biopsy specimen showed a mild lymphohistiocytic perivascular infiltrate of cells in the papillary and mid dermis and deposition of fibrinogen around the capillary vessels. Subacute necrotizing lymphadenitis responds to oral corticosteroid therapy but not to antibiotics.
Ikeda
S
S
Department of Dermatology, Juntendo University School of Medicine, Tokyo, Japan.
Ogawa
H
H
D000208:Acute Disease; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008199:Lymphadenitis / Q000188:drug therapy / Q000473:pathology*; D008875:Middle Aged; D009336:Necrosis; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D012737:Sex Factors; D012867:Skin / Q000473:pathology
D011239:Prednisolone