title: Chronic achilles paratenonitis with tendinosis: an experimental model in the rabbit.
abstract: An experimental model for inducing chronic Achilles paratenonitis with tendinosis in the rabbit is presented. Thirteen rabbits were exercised in a kicking machine producing passive flexions and extensions of the ankle joint. Active contractions of the triceps surae muscles were induced by electric stimulation via surface electrodes. The animals were exercised for 5 to 6 weeks, with a rate of 150 flexions and extensions per minute for 2 h, three times a week. Light microscopic examination showed degenerative changes of the tendon, and increased number of capillaries, infiltrates of inflammatory cells, edema, and fibrosis in the paratenon. We conclude that chronic Achilles paratenonitis with tendinosis can be experimentally induced in a standardized manner in rabbits.
authors.affiliation: Department of Hand and Plastic Surgery, University of Umeå, Sweden.
authors.forename: C
authors.initials: C
authors.lastname: Backman
authors.forename: L
authors.initials: L
authors.lastname: Boquist
authors.forename: J
authors.initials: J
authors.lastname: Fridén
authors.forename: R
authors.initials: R
authors.lastname: Lorentzon
authors.forename: G
authors.initials: G
authors.lastname: Toolanen
mesh_terms: D000125:Achilles Tendon / Q000473:pathology*; D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D008297:Male; D011817:Rabbits; D052256:Tendinopathy / Q000150:complications* / Q000473:pathology; D013708:Tendon Injuries / Q000150:complications* / Q000473:pathology