[Possibilities of more accurate evaluation of the degree of myocardial damage and the completeness of reparative processes in patients with acute myocardial infarction by studying the characteristics of monocytes].
Patients with acute myocardial infarction (MI) were found to have hyper- and dyslipidemias independent of the depth of myocardial lesions and, in addition, to have more severe granulo- and monocytosis, higher adhesive and phagocytic ability of blood mononuclears that are typical for penetrating MI. Examining biochemical and immunological indices in the time-course of acute MI enables one to assess the completeness of reparative process in the myocardium. A significant and long-term monocyte activation in patients with penetrating MI seems to be due to an extended necrotic area and further formation of a focus aseptic inflammation, from whose the product that stimulate the production and function of blood monocytes are absorbed.
Krasil'nikova
E I
EI
Almazov
V A
VA
Freĭdlin
I S
IS
Magracheva
E Ia
EIa
Vasil'eva
L E
LE
D000328:Adult; D002478:Cells, Cultured; D006801:Humans; D066298:In Vitro Techniques; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000276:immunology*; D009203:Myocardial Infarction / Q000276:immunology* / Q000473:pathology / Q000534:rehabilitation; D009206:Myocardium / Q000473:pathology*; D010587:Phagocytosis / Q000276:immunology*; D011379:Prognosis
Vozmozhnosti utochneniia glubiny povrezhdeniia miokarda i zavershennosti reparativnykh protsessov u bol'nykh ostrym infarktom miokarda pri izuchenii kharakteristik monotsitov krovi.