Lymphocyte concanavalin A capping in hereditary cerebral haemorrhage with amyloidosis--Dutch type.
Lymphocyte capping with concanavalin A was studied in 11 patients with hereditary cerebral haemorrhage with amyloidosis (Dutch type) and 10 controls. No difference in capping was found between patients and controls. Abnormal lymphocyte concanavalin A capping has been reported in patients with the Icelandic type of cerebral amyloidosis and in patients with Alzheimer's disease, a disease in which cerebral amyloid angiopathy can also be found. The results suggest a difference in pathogenesis between the Dutch type of cerebral amyloidosis and the other amyloid diseases.
Haan
J
J
Department of Neurology, University Hospital, Leiden, The Netherlands.
Demmers
R T
RT
Buruma
O J
OJ
Roos
R A
RA
D000368:Aged; D000686:Amyloidosis / Q000145:classification / Q000150:complications / Q000235:genetics / Q000276:immunology*; D002543:Cerebral Hemorrhage / Q000209:etiology / Q000235:genetics / Q000276:immunology*; D003078:Colchicine / Q000494:pharmacology; D003208:Concanavalin A; D004148:Dioxolanes / Q000494:pharmacology; D005260:Female; D006801:Humans; D007152:Immunologic Capping / Q000187:drug effects; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008722:Methods; D008875:Middle Aged
D004148:Dioxolanes; D003208:Concanavalin A; C040422:tubulazole; D003078:Colchicine