Direct high-performance liquid chromatographic analysis of p-hydroxyphenyl-phenylhydantoin glucuronide, the final metabolite of phenytoin, in human serum and urine.
Vree
T B
TB
Department of Clinical Pharmacy, Academic Hospital Nijmegen Sint Radboud, Nijmegen, The Netherlands.
Steegers-Theunissen
R P
RP
Baars
A M
AM
Hekster
Y A
YA
D002851:Chromatography, High Pressure Liquid; D004827:Epilepsy / Q000188:drug therapy / Q000378:metabolism; D005965:Glucuronates / Q000032:analysis* / Q000097:blood / Q000652:urine; D005966:Glucuronidase; D006801:Humans; D010672:Phenytoin / Q000031:analogs & derivatives* / Q000032:analysis / Q000097:blood / Q000378:metabolism* / Q000627:therapeutic use / Q000652:urine; D013237:Stereoisomerism
D005965:Glucuronates; C001419:hydroxyphenytoin; D010672:Phenytoin; D005966:Glucuronidase