Timed sequential chemotherapy following ifosfamide-induced kinetic recruitment in refractory ovarian cancer.
A total of 22 relapsed or refractory ovarian cancer patients were treated with ifosfamide-containing polychemotherapy. Kinetic analyses were done to evaluate the tumor-cell-recruiting potential of the alkylating agent. Our study shows that ifosfamide can enhance tumor proliferative activity in pretreated ovarian cancers.
Rosso
R
R
Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy.
Alama
A
A
Repetto
L
L
Conte
P F
PF
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage*; D007700:Kinetics; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000473:pathology
D007069:Ifosfamide