title: [Skeletal structures of the cell nucleus in the normal state and pathology].
abstract: The structure and composition of the nuclear skeleton (nuclear matrix) are considered. The literature data are referred to and the findings of the original author's research on the associations of the nuclear matrix with DNA, its involvement in the control of replication and transcription occurring on the nuclear matrix sites. Special attention is given to the protein composition of the nuclear matrix, and to its changes in tumour growth, virus infection, as well as during mitosis and embryonal development.
authors.forename: I B
authors.initials: IB
authors.lastname: Zbarskiĭ
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000235:genetics / Q000502:physiology; D002455:Cell Division / Q000502:physiology; D002467:Cell Nucleus / Q000502:physiology / Q000648:ultrastructure*; D004261:DNA Replication / Q000502:physiology*; D006801:Humans; D008114:Liver Neoplasms, Experimental / Q000235:genetics / Q000648:ultrastructure*; D015530:Nuclear Matrix / Q000502:physiology / Q000648:ultrastructure*; D009687:Nuclear Proteins / Q000378:metabolism*; D051381:Rats; D014158:Transcription, Genetic / Q000502:physiology*; D014777:Virus Diseases / Q000235:genetics / Q000473:pathology*
chemical_list: D009687:Nuclear Proteins
vernacular_title: Skeletnye struktury kletochnogo iadra v norme i pri patologii.