title: Effects of nebulized lignocaine on the intraocular pressure responses to tracheal intubation.
abstract: We have examined the effect of preoperative administration of nebulized lignocaine or saline on the intraocular pressure (IOP) response to tracheal intubation in 20 adults. In the saline group, tracheal intubation was associated with a significant increase in IOP above control and preintubation values (P less than 0.01); in the lignocaine group there was no change in IOP following intubation. After intubation, IOP was significantly less in the lignocaine group than in the saline group (P less than 0.05).
authors.affiliation: Department of Anaesthesia, Royal Liverpool Hospital.
authors.forename: S M
authors.initials: SM
authors.lastname: Mostafa
authors.forename: J R
authors.initials: JR
authors.lastname: Wiles
authors.forename: T
authors.initials: T
authors.lastname: Dowd
authors.forename: R
authors.initials: R
authors.lastname: Bates
authors.forename: S
authors.initials: S
authors.lastname: Bricker
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D007442:Intubation, Intratracheal; D008012:Lidocaine / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D009330:Nebulizers and Vaporizers; D011292:Premedication; D011897:Random Allocation
chemical_list: D008012:Lidocaine