[The rate and duration of the yield of labelled biologically active factors from ethylenevinylacetate copolymer].
The possibility to use polymer carrier for transport of retinol (R) and the peptide enhancing regeneration of head section of Hydra (PH) has been studied. Efflux of R occurs both through intact polymer and through pores formed in the polymer by albumin, whereas PH is not able to penetrate the polymer and its rate of efflux is determined by the amount of albumin added. The efflux of both R and PH changes with time in a stepwise manner. The total yield of R and PH after 37 days varied in the range of 17 to 40% and 1 to 95%, respectively, in different experimental conditions.
Znoĭko
S L
SL
Miloserdov
Iu V
IuV
Pozdniakov
S P
SP
D000818:Animals; D004058:Diffusion; D004337:Drug Carriers; D005025:Ethylene Dichlorides / Q000494:pharmacology; D006829:Hydra / Q000187:drug effects / Q000502:physiology; D008970:Molecular Weight; D009479:Neuropeptides / Q000493:pharmacokinetics; D010209:Paper; D011145:Polyvinyls / Q000494:pharmacology*; D011761:Pyrrolidonecarboxylic Acid / Q000031:analogs & derivatives; D012038:Regeneration / Q000187:drug effects / Q000502:physiology; D012709:Serum Albumin / Q000494:pharmacology; D013997:Time Factors; D014801:Vitamin A / Q000493:pharmacokinetics
D004337:Drug Carriers; D005025:Ethylene Dichlorides; D009479:Neuropeptides; D011145:Polyvinyls; D012709:Serum Albumin; D014801:Vitamin A; C016438:ethylenevinylacetate copolymer; C024565:ethylene dichloride; C032522:head activator peptide; D011761:Pyrrolidonecarboxylic Acid
Izuchenie skorosti i prodolzhitel'nosti vykhoda mechenykh biologicheski aktivnykh faktorov iz kopolimera étilenvinilatsetata.