title: Dilation and evacuation for second-trimester genetic pregnancy termination.
abstract: Dilation and evacuation (D&E) is the most common procedure for second-trimester pregnancy termination currently used by United States obstetrician-gynecologists. Although this method carries morbidity and mortality rates significantly lower than methods requiring labor induction, the procedure most commonly used for second-trimester genetic terminations seems to be labor induction (eg, vaginal prostaglandin suppositories). Many geneticists appear reluctant to recommend D&E over induction methods of pregnancy termination because they perceive that fetal abnormalities cannot be consistently confirmed by evaluation of the products of conception obtained by D&E. We report here 60 consecutive patients who underwent D&E (14-22 weeks' gestation) after detection of fetal abnormalities. The prenatal diagnoses were confirmed in all cases. Our experience thus indicates that D&E is reliable in confirming most prenatal diagnoses and should be the procedure of choice when second-trimester pregnancy termination is chosen because of fetal abnormalities.
authors.affiliation: Department of Obstetrics and Gynecology, University Physicians Foundation, Memphis, Tennessee.
authors.forename: L P
authors.initials: LP
authors.lastname: Shulman
authors.forename: F W
authors.initials: FW
authors.lastname: Ling
authors.forename: C M
authors.initials: CM
authors.lastname: Meyers
authors.forename: D R
authors.initials: DR
authors.lastname: Shanklin
authors.forename: J L
authors.initials: JL
authors.lastname: Simpson
authors.forename: S
authors.initials: S
authors.lastname: Elias
mesh_terms: D000025:Abortion, Eugenic / Q000379:methods*; D000028:Abortion, Induced / Q000379:methods*; D000013:Congenital Abnormalities / Q000175:diagnosis; D004106:Dilatation / Q000379:methods; D005113:Extraction, Obstetrical / Q000379:methods; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis; D006801:Humans; D011247:Pregnancy; D011262:Pregnancy Trimester, Second