Trisomy 12 in benign fibroma and granulosa cell tumor of the ovary.
Chromosome studies were performed on two benign ovarian fibromas and one ovarian granulosa cell tumor. Trisomy 12 was found in all three cases, and additional abnormalities, monosomy 22 and the translocation t(3;9;21), were also observed in the granulosa cell tumor.
Leung
W Y
WY
Department of Human Genetics, Yale University School of Medicine, New Haven, Connecticut 06510-8005.
Schwartz
P E
PE
Ng
H T
HT
Yang-Feng
T L
TL
D000368:Aged; D002881:Chromosomes, Human, Pair 12; D002891:Chromosomes, Human, Pair 21; D002892:Chromosomes, Human, Pair 22; D002893:Chromosomes, Human, Pair 3; D002899:Chromosomes, Human, Pair 9; D005260:Female; D005350:Fibroma / Q000235:genetics*; D006106:Granulosa Cell Tumor / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D008875:Middle Aged; D009006:Monosomy; D010051:Ovarian Neoplasms / Q000235:genetics*; D014178:Translocation, Genetic; D014314:Trisomy