(Avid) rosette-forming cells as evidence for cellular immunity following measles virus vaccination in monkeys: correlation with the presence of haemagglutination inhibitory antibodies.
Lymphocytes characterized by in vitro rosette formation with sheep erythrocytes were enumerated in blood of normal and measles virus-vaccinated monkeys. Rosetting lymphocyte counts increased significantly as a result of vaccination. Concomitantly, HAI-antibody, undetectable before vaccination, became detectable, suggesting that the simple and inexpensive technique of enumerating rosetting lymphocytes can be used as an alternative to other more cumbersome and expensive methods for evaluation of development of cell-mediated immunity following measles virus vaccination.
Eghafona
N O
NO
Department of Microbiology, Ahmadu Bello University, Zaria, Nigeria.
Emejuaiwe
S O
SO
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D004901:Erythrocebus patas; D006385:Hemagglutination Inhibition Tests; D007958:Leukocyte Count; D008214:Lymphocytes / Q000276:immunology*; D008459:Measles virus / Q000276:immunology*; D012397:Rosette Formation / Q000379:methods; D014611:Vaccination
D000914:Antibodies, Viral