Carbamazepine-induced pseudolymphoma and immune dysregulation.
Pseudolymphoma is a condition that closely resembles malignant lymphoma, both clinically and on histopathological examination. Immunological cell typing is necessary for correct diagnosis. We present here the case of a patient with carbamazepine-induced generalized lymphadenopathy, hepatosplenomegaly, anaemia, abnormal differential leucocyte count, and hypergammaglobulinaemia. There was evidence of severe immune dysregulation. All abnormalities subsided spontaneously after withdrawal of carbamazepine and the patient remained in good health afterwards.
Sinnige
H A
HA
Department of Internal Medicine, Sophia Ziekenhuis Zwolle, The Netherlands.
Boender
C A
CA
Kuypers
E W
EW
Ruitenberg
H M
HM
D000368:Aged; D002220:Carbamazepine / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007154:Immune System Diseases / Q000139:chemically induced*; D008223:Lymphoma / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology
D002220:Carbamazepine