title: Caries preventive effect of fluoride varnish applications performed two or four times a year.
abstract: The efficacy of Duraphat varnish applications performed two or four times a year was compared in a 2-yr clinical trial. 254 children aged 9-13 yr and having higher than average DMFS values participated in the study. The children were randomly divided into two treatment groups. Clinical and radiographical examinations were performed at baseline and after 2 yr by one dentist. For the group receiving applications every 3 months, the 2-yr DMFS increment was 2.90 (SD 4.45) and for the group receiving applications every 6 months, 2.92 (4.47). There were no significant differences in DMFS increments between the groups for any type of tooth surfaces. Neither was there any difference between the groups when the children were divided into two subgroups on the basis of baseline DMFS values. The increments for the children with high (greater than or equal to 10) baseline DMFS values were 4.25 (4.81) and 4.30 (5.53) in the groups receiving applications four times and twice a year, respectively. The results suggest that fluoride varnish applications performed more frequently than twice a year may not provide additional caries protection in a population with relatively low caries activity.
authors.affiliation: Faculty of Dentistry, University of Kuopio, Finland.
authors.forename: L
authors.initials: L
authors.lastname: Seppä
authors.forename: T
authors.initials: T
authors.lastname: Tolonen
mesh_terms: D000293:Adolescent; D002648:Child; D004245:DMF Index; D003731:Dental Caries / Q000517:prevention & control*; D005459:Fluorides / Q000008:administration & dosage / Q000627:therapeutic use; D005460:Fluorides, Topical / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D011897:Random Allocation; D012969:Sodium Fluoride / Q000008:administration & dosage / Q000627:therapeutic use*; D013607:Tablets; D013997:Time Factors; D014100:Toothpastes
chemical_list: D005460:Fluorides, Topical; D013607:Tablets; D014100:Toothpastes; C023807:sodium fluoride topical preparation; D012969:Sodium Fluoride; D005459:Fluorides