title: Fetal cystic hygromata: insights gained from fetal blood sampling.
abstract: Twelve second-trimester fetuses with cystic hygroma underwent fetal blood sampling for rapid karyotyping, haematologic evaluation, and blood gas analysis. An abnormal karyotype was found in seven cases: monosomy X in five, trisomy 21 in one, and trisomy 13 in the other. Eight of ten fetuses undergoing blood gas analysis showed hypoxaemia, five of which were growth-retarded. Nine pregnancies were terminated. Of the remaining three, only one fetus survived the perinatal period.
authors.affiliation: Royal Postgraduate Medical School, Institute of Obstetrics and Gynecology, Queen Charlotte's Chelsea Hospital, London, U.K.
authors.forename: Y
authors.initials: Y
authors.lastname: Tannirandorn
authors.forename: U
authors.initials: U
authors.lastname: Nicolini
authors.forename: P C
authors.initials: PC
authors.lastname: Nicolaidis
authors.forename: N M
authors.initials: NM
authors.lastname: Fisk
authors.forename: S
authors.initials: S
authors.lastname: Arulkumaran
authors.forename: C H
authors.initials: CH
authors.lastname: Rodeck
mesh_terms: D001784:Blood Gas Analysis; D004909:Erythrocyte Indices; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D005315:Fetal Diseases / Q000175:diagnosis*; D006801:Humans; D007621:Karyotyping; D008202:Lymphangioma / Q000175:diagnosis*; D011247:Pregnancy; D011262:Pregnancy Trimester, Second