Hyperthyroidism during pregnancy due to coexistence of struma ovarii and Graves' disease.
A patient with hyperthyroid Graves' disease and struma ovarii is described. She had pre-existing Graves' disease and positive thyrotrophin receptor antibody. She was treated with radioactive iodine 5 months before she became pregnant. Paripartum she had torsion of an ovarian cyst with histological evidence of a functional struma ovarii. Immediate exacerbation of her thyrotoxic state was observed after operation as a result of release of thyroid hormone from the tumour. It is postulated that the tumour was stimulated by circulating thyrotrophin receptor antibody.
Kung
A W
AW
Department of Medicine, University of Hong Kong, Queen Mary Hospital.
Ma
J T
JT
Wang
C
C
Young
R T
RT
D000328:Adult; D000906:Antibodies / Q000032:analysis; D005260:Female; D006111:Graves Disease / Q000150:complications* / Q000532:radiotherapy; D006801:Humans; D006980:Hyperthyroidism / Q000209:etiology*; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D010051:Ovarian Neoplasms / Q000150:complications*; D011247:Pregnancy; D011248:Pregnancy Complications; D011252:Pregnancy Complications, Neoplastic; D011989:Receptors, Thyrotropin / Q000276:immunology; D013330:Struma Ovarii / Q000150:complications*
D000906:Antibodies; D007457:Iodine Radioisotopes; D011989:Receptors, Thyrotropin