Does inhibition of K+ transport in glial cells by local anaesthetics contribute to seizures?
Shokeir
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O
Department of Anaesthesia, University of Saskatchewan, Saskatoon, Canada.
Code
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Hertz
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L
D000779:Anesthetics, Local / Q000633:toxicity*; D000818:Animals; D001253:Astrocytes / Q000187:drug effects*; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D005917:Globus Pallidus / Q000166:cytology; D008012:Lidocaine / Q000633:toxicity; D051379:Mice; D008815:Mice, Inbred Strains; D011188:Potassium / Q000378:metabolism; D015221:Potassium Channels / Q000187:drug effects*; D011343:Procaine / Q000633:toxicity; D012640:Seizures / Q000139:chemically induced*; D013748:Tetracaine / Q000633:toxicity
D000779:Anesthetics, Local; D015221:Potassium Channels; D013748:Tetracaine; D011343:Procaine; D008012:Lidocaine; D011188:Potassium