[Intraperitoneal hyperthermic chemotherapy in the treatment of peritoneal carcinosis of digestive origin. A case report and physiopathology].
The authors describe their first experience of IP hyperthermochemiotherapy using mitomycin C under hypothermic coverage at 32 degrees C, in a female patient with peritoneal carcinosis secondary to stomach cancer. Postoperative complications were not observed. Tested mitomycin blood levels evidenced good absorption via the peritoneal route. 4 months later, the patient is doing well and the authors are propounding the method be started in a series of patients, in order to assess its long-term efficacy.
Gilly
F N
FN
Service de Chirurgie Générale et Thoracique, Centre Hospitalier Lyon-Sud, Pierre Bénite.
Sayag
A C
AC
Carry
P Y
PY
Braillon
G
G
Roche
M
M
James
I
I
Voloch
A
A
Panteix
G
G
D000328:Adult; D002277:Carcinoma / Q000188:drug therapy* / Q000556:secondary; D002985:Clinical Protocols; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods; D007036:Hypothermia, Induced / Q000379:methods; D007263:Infusions, Parenteral / Q000379:methods*; D008937:Mitomycins / Q000008:administration & dosage*; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000556:secondary; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D013274:Stomach Neoplasms / Q000473:pathology
D008937:Mitomycins
Chimio-hyperthermie intra-péritonéale (CHIP) dans le traitement des carcinoses péritonéales d'origine digestive. Rapport d'une observation et données physiopathologiques.