title: Acute management of intracranial hemorrhage in patients receiving thrombolytic therapy: case reports.
abstract: Intracranial hemorrhage is an uncommon complication of antithrombotic therapy. We present two patients who suffered life-threatening intracranial bleeding as a complication of thrombolytic/anticoagulant treatment. Early diagnosis and treatment appear to be crucial factors for survival. We suggest an approach to perioperative management for intracranial hemorrhage resulting from antithrombotic therapy.
authors.affiliation: Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine and Hospital, Baltimore, Maryland.
authors.forename: S M
authors.initials: SM
authors.lastname: Eleff
authors.forename: C
authors.initials: C
authors.lastname: Borel
authors.forename: W R
authors.initials: WR
authors.lastname: Bell
authors.forename: D M
authors.initials: DM
authors.lastname: Long
mesh_terms: D000368:Aged; D002543:Cerebral Hemorrhage / Q000209:etiology* / Q000601:surgery; D005260:Female; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013300:Streptokinase / Q000009:adverse effects*; D015912:Thrombolytic Therapy / Q000009:adverse effects*; D014568:Urokinase-Type Plasminogen Activator / Q000009:adverse effects*
chemical_list: D006493:Heparin; D013300:Streptokinase; D014568:Urokinase-Type Plasminogen Activator