[Experimental studies on treating anti-anaphylactic asthma with a qingfei bushen decoction].
On the basis of satisfying clinical effects of Qingfei Bushen Decoction, the authors carried out experimental studies with animals on anti-anaphylactic asthma with the decoction (200% condensed) to probe into the effective mechanism. The experimental results showed that the condensed decoction could effectively suppress rats' passive cutaneous anaphylaxis and guinea pigs' anaphylactic asthma allergized by egg protein. The results also showed that the condensed decoction obviously resisted the guinea pigs' bronchial spasm induced by histamine and acetylcholine, and it could significantly promote the multiplication of rats' thymus gland. Thymus gland multiplication and immunomodulating action are also discussed in the paper.
Chen
L
L
Zhejiang College of TCM, Hangzhou.
Zhang
M
M
Li
J
J
D000109:Acetylcholine / Q000502:physiology; D000818:Animals; D001249:Asthma / Q000188:drug therapy* / Q000276:immunology; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006168:Guinea Pigs; D006632:Histamine / Q000502:physiology; D008297:Male; D010323:Passive Cutaneous Anaphylaxis; D051381:Rats; D011919:Rats, Inbred Strains
D004365:Drugs, Chinese Herbal; D006632:Histamine; D000109:Acetylcholine