Detection of the time of ovulation in clomiphene stimulated cycles with an easily applicable urine test.
40 cycles of 35 patients, 38 of which were stimulated with clomiphen, were monitored with the LH-Colortest. This urine test, which was applied by the patients themselves twice daily, detected the LH peak in 33 out of 34 cycles with proven ovulation. In 24 cycles, the LH peak was registered in urine already fourteen hours before it showed in the daily serum controls. The urine LH peak (the test becomes positive at an LH concentration of at least 50 IU/ml) was observed on cycle day 13.6. on average while the corresponding LH peak in serum occurred on cycle day 14.2 on average. The sensitivity of the LH-Colortest was 97.2% and its specificity was 100%.
Lehmann-Willenbrock
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Department of Gynecology and Obstetrics, University of Kiel.
Riedel
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HH
Langenbucher
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Grillo
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M
D000328:Adult; D000372:Agglutination Tests; D002996:Clomiphene / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy* / Q000652:urine; D007986:Luteinizing Hormone / Q000652:urine*; D010060:Ovulation / Q000187:drug effects*; D010061:Ovulation Detection / Q000379:methods*; D011933:Reagent Kits, Diagnostic
D011933:Reagent Kits, Diagnostic; D002996:Clomiphene; D007986:Luteinizing Hormone