Familial spontaneous pneumothorax.
In a three generation family with 27 members we examined a relationship could be found between spontaneous pneumothorax and HLA-haplotypes, alpha 1-antitrypsin phenotypes or concentration or lung volumes and ventilatory capacity. Eight individuals in the family suffered from spontaneous pneumothorax. No relationship with the investigated markers could be found in this informative family. All patients showed normal lung volumes and ventilatory capacity after recovery.
Lenler-Petersen
P
P
Dept. of Pulmonary Diseases, Skive Hospital, Denmark.
Grunnet
N
N
Jespersen
T W
TW
Jaeger
P
P
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006680:HLA Antigens / Q000235:genetics; D006239:Haplotypes; D006801:Humans; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D010641:Phenotype; D011030:Pneumothorax / Q000235:genetics* / Q000503:physiopathology; D000515:alpha 1-Antitrypsin / Q000378:metabolism
D006680:HLA Antigens; D000515:alpha 1-Antitrypsin