Serum prolactin levels during extended cocaine abstinence.
Following a report indicating almost a 100% risk for hyperprolactinemia in cocaine users after 1 month of abstinence, the authors determined the serum prolactin concentrations of 23 male inpatients who had abstained from cocaine for 2-43 weeks. None showed high prolactin levels; this places the incidence below 12.3% with 95% confidence. These results imply that persistent hyperprolactinemia requires a medical explanation other than cocaine abstinence itself.
Swartz
C M
CM
Department of Psychiatry, University of Health Sciences/Chicago Medical School, IL 60064.
Breen
K
K
Leone
F
F
D001971:Bromocriptine / Q000627:therapeutic use; D003042:Cocaine; D006760:Hospitalization; D006801:Humans; D006966:Hyperprolactinemia / Q000097:blood*; D008297:Male; D011388:Prolactin / Q000097:blood*; D019966:Substance-Related Disorders / Q000097:blood / Q000534:rehabilitation*; D013808:Therapeutic Community
D001971:Bromocriptine; D011388:Prolactin; D003042:Cocaine