Alcohol drinking, food and fluid intakes and body weight gain in rats.
Body weight (BW) and food and fluid intakes were compared in rats receiving a 10% or a 20% alcohol solution as the only source of fluid and in water-drinking rats. Intake of the 20% alcohol solution caused a marked reduction in BW gain without affecting energy intake. Meal size (alcohol plus powder) and meal number over the 24-hour circadian cycle were not modified. Examination of simultaneous recordings of eating and drinking revealed that preprandial drinking increased significantly in rats drinking alcohol solutions. The reduced BW gain may be due to increased energy expenditure through increased alcohol metabolism and/or postprandial thermogenesis. Thus, in rats drinking alcohol solutions up to 20%, energy input is unchanged while energy output is increased.
Larue-Achagiotis
C
C
Laboratoire de Neurobiologie de la Nutrition, Université Pierre et Marie Curie, Paris, France.
Poussard
A M
AM
Louis-Sylvestre
J
J
D000428:Alcohol Drinking / Q000502:physiology*; D000818:Animals; D001834:Body Water / Q000187:drug effects; D002940:Circadian Rhythm; D004326:Drinking / Q000187:drug effects*; D004435:Eating / Q000187:drug effects*; D002149:Energy Intake; D000431:Ethanol / Q000494:pharmacology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D015430:Weight Gain / Q000187:drug effects*
D000431:Ethanol