2-Aminooxazolines, I: Crystal and molecular structure of 5-(1-aryl-4-piperazino)methyl-substituted derivatives with antidepressant activity.
The structure of two 5-(1-aryl-4-piperazino)methyl-2-aminooxazolines were determined by X-ray crystallography. An amino form is preponderant in a free base whereas an imino form is preponderant in a salt. The molecular conformations were studied by molecular mechanics.
Jarry
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Laboratoire de Chimie Physique, Faculté des Sciences Pharmaceutiques, Université de Bordeaux II, France.
Bosc
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Ouhabi
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J
Carpy
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D000928:Antidepressive Agents / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D003460:Crystallization; D008968:Molecular Conformation; D010080:Oxazoles / Q000138:chemical synthesis* / Q000494:pharmacology
D000928:Antidepressive Agents; D010080:Oxazoles; C064245:COR 3286; C056984:COR 32-24