title: [Progressive multifocal leukoencephalopathy associated with leukopenia of unknown (iatrogenic?) origin].
abstract: Progressive multifocal leukoencephalopathy is a virtually always opportunistic infection of central nervous system caused by papova viruses, which clinically presents with symptoms and signs of involvement of different encephalic levels. We report a case with a double interest: on the one hand, both clinical features and lesions were limited to the brainstem and cerebellum; on the other hand, the disease developed in a previously healthy female in whom laboratory evidence of immunodeficiency of unknown origin was demonstrated. A reason for immunodeficiency was also not found at autopsy, being speculated that it could have been iatrogenically associated with antidepressant drugs.
authors.affiliation: Servicio y Cátedra de Neurología, Hospital de Cruces, Facultad de Medicina y Odontología, Universidad del País Vasco-Euskal Herriko Unibersitatea.
authors.forename: M
authors.initials: M
authors.lastname: Gómez Beldarrain
authors.forename: M
authors.initials: M
authors.lastname: Pérez-Bas
authors.forename: M
authors.initials: M
authors.lastname: Rosell
authors.forename: J
authors.initials: J
authors.lastname: Tánago
authors.forename: I
authors.initials: I
authors.lastname: Forcadas
authors.forename: J J
authors.initials: JJ
authors.lastname: Zarranz
mesh_terms: D001933:Brain Stem; D002531:Cerebellum; D005260:Female; D006801:Humans; D007968:Leukoencephalopathy, Progressive Multifocal / Q000150:complications*; D007970:Leukopenia / Q000150:complications* / Q000209:etiology; D008875:Middle Aged
vernacular_title: Leucoencefalopatía multifocal progresiva asociada a leucopenia de origen desconocido (yatrógena?).