title: Chloral hydrate in intractable status epilepticus.
abstract: Five adult patients were admitted to the neurological department in a state of status epilepticus. All were treated unsuccessfully with IV diazepam and diphenylhydantoin. Administration of sodium valporate or phenobarbital also was ineffective. However, after treatment with intrarectal chloral hydrate, all seizures ceased. The excellent effect of this drug was proved both clinically and electrodiagnostically. Discussed is the possibility of using chloral hydrate to treat patients with status epilepticus in whom conventional treatment has failed.
authors.affiliation: Department of Neurology, Edith Wolfson Medical Center, Holon, Israel.
authors.forename: Y
authors.initials: Y
authors.lastname: Lampl
authors.forename: Y
authors.initials: Y
authors.lastname: Eshel
authors.forename: R
authors.initials: R
authors.lastname: Gilad
authors.forename: I
authors.initials: I
authors.lastname: Sarova-Pinchas
mesh_terms: D000285:Administration, Rectal; D000328:Adult; D002697:Chloral Hydrate / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D004357:Drug Synergism; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013226:Status Epilepticus / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed
chemical_list: D002697:Chloral Hydrate