A pilot study of metoclopramide, dexamethasone, diphenhydramine and acupuncture in women treated with cisplatin.
A total of 26 women who submitted to cisplatin chemotherapy received as antiemetic treatment a combination of metoclopramide, dexamethasone and diphenhydramine. Acupuncture according to traditional Chinese medicine was also carried out. The results were compared with those obtained in a similar group of women with cancer, who were treated in the same setting with the same antiemetic combination but without additional acupuncture. Acupuncture was shown to increase complete protection from nausea and to decrease the intensity and duration of nausea and vomiting. However, the difficulties of performing acupuncture routinely in daily practice are a hindrance to its wider use.
Aglietti
L
L
Medical Oncology Division, Ospedale Policlinico, Perugia, Italy.
Roila
F
F
Tonato
M
M
Basurto
C
C
Bracarda
S
S
Picciafuoco
M
M
Ballatori
E
E
Del Favero
A
A
D015670:Acupuncture Therapy; D000328:Adult; D000368:Aged; D002945:Cisplatin / Q000009:adverse effects*; D003131:Combined Modality Therapy; D003907:Dexamethasone / Q000627:therapeutic use*; D004155:Diphenhydramine / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008787:Metoclopramide / Q000627:therapeutic use*; D008875:Middle Aged; D013997:Time Factors; D014839:Vomiting / Q000139:chemically induced / Q000628:therapy
D003907:Dexamethasone; D004155:Diphenhydramine; D008787:Metoclopramide; D002945:Cisplatin