Combined treatment of ocular squamous cell carcinoma in a horse, using radiofrequency hyperthermia and interstitial 198Au implants.
Unilateral ocular squamous cell carcinoma in a horse was treated effectively with a combination of repeated radiofrequency hyperthermia and interstitial radiotherapy. These 2 modalities of treatment are synergistic. Interstitial irradiation was achieved, using 198Au implants to deliver a total dose of approximately 5,000 rads/implant over an area of 1 cm2. Radio frequency hyperthermia was repeated 3 times, and radiotherapy was used twice. Treatment resulted in complete regression of the tumor, and ocular complications have not been seen.
Wilkie
D A
DA
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University, Columbus 43210-1089.
Burt
J K
JK
D000818:Animals; D001918:Brachytherapy / Q000662:veterinary; D002294:Carcinoma, Squamous Cell / Q000628:therapy / Q000662:veterinary*; D003131:Combined Modality Therapy; D005134:Eye Neoplasms / Q000628:therapy / Q000662:veterinary*; D006050:Gold Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use*; D006734:Horse Diseases / Q000628:therapy*; D006736:Horses; D006979:Hyperthermia, Induced / Q000662:veterinary*; D008297:Male
D006050:Gold Radioisotopes