title: Idiopathic pulmonary fibrosis. A rare cause of scintigraphic ventilation-perfusion mismatch.
abstract: A case of idiopathic pulmonary fibrosis with multiple areas of mismatch on ventilation-perfusion lung imaging in the absence of pulmonary embolism is presented. Idiopathic pulmonary fibrosis is one of the few nonembolic diseases producing a pulmonary ventilation-perfusion mismatch. In this condition, chest radiographs may not detect the full extent of disease, and xenon-133 ventilation imaging may be relatively insensitive to morbid changes in small airways. Thus, when examining patients with idiopathic pulmonary fibrosis, one should be aware that abnormal perfusion imaging patterns without matching ventilation abnormalities are not always due to embolism. In this setting, contrast pulmonary angiography is often needed for accurate differential diagnosis.
authors.affiliation: Department of Radiology, Medical College of Wisconsin, Milwaukee.
authors.forename: W T
authors.initials: WT
authors.lastname: Pochis
authors.forename: A Z
authors.initials: AZ
authors.lastname: Krasnow
authors.forename: B D
authors.initials: BD
authors.lastname: Collier
authors.forename: M W
authors.initials: MW
authors.lastname: Mewissen
authors.forename: U A
authors.initials: UA
authors.lastname: Almagro
authors.forename: R S
authors.initials: RS
authors.lastname: Hellman
authors.forename: A T
authors.initials: AT
authors.lastname: Isitman
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000000981:diagnostic imaging; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging*; D011658:Pulmonary Fibrosis / Q000000981:diagnostic imaging*; D011667:Pulmonary Veins / Q000000981:diagnostic imaging; D011859:Radiography; D011877:Radionuclide Imaging; D014692:Ventilation-Perfusion Ratio; D014980:Xenon Radioisotopes
chemical_list: D014980:Xenon Radioisotopes