[The effect of combined ALL therapy in childhood on body growth].
Female ALL long-term survivors who received cranial telecobalt radiation under the conditions of Therapy Study III of the Study Group on "Paediatric Haematology/Oncology" showed a significant reduction in adult height. On completion of therapy a drop in growth can already be observed in female ALL patients. This limitation on growth can probably be attributed to a disturbance in the hypothalamus-hypophysis system and to reduced GH secretion as a result of radiation.
Reddemann
H
H
Hämatologisch/Onkologische Abt., Ernst-Moritz-Arndt-Universität, Greifswald.
Beyer
B
B
D001827:Body Height / Q000502:physiology*; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000401:mortality / Q000503:physiopathology* / Q000628:therapy; D012189:Retrospective Studies; D012727:Sex Characteristics
Zum Einfluss der komplexen ALL-Therapie im Kindesalter auf das Körperwachstum.