Antiphospholipid antibodies and necrotizing purpura.
A 30-year-old woman with recurrent necrotizing purpura on the legs which did not fit, to our knowledge, within any distinctive pathological entity, is described. Laboratory investigations disclosed a mild thrombocytopenia and antiphospholipid antibodies, i.e. lupus anticoagulant and anticardiolipin. Cutaneous lesions may be an early marker of the antiphospholipid antibody syndrome.
Naldi
L
L
Department of Dermatology, Ospedali Riuniti di Bergamo, Italy.
Marchesi
L
L
Finazzi
G
G
Locati
F
F
Cainelli
T
T
D000328:Adult; D001323:Autoantibodies / Q000032:analysis*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D009336:Necrosis; D010743:Phospholipids / Q000276:immunology*; D011693:Purpura / Q000276:immunology* / Q000473:pathology; D012008:Recurrence; D013577:Syndrome
D001323:Autoantibodies; D010743:Phospholipids