title: Electroretinographic findings in panretinal photocoagulation for diabetic retinopathy. A randomized study with blue-green argon and red krypton lasers.
abstract: A total of 16 patients (16 eyes) with type II diabetes mellitus and proliferative retinopathy were studied electroretinographically before panretinal photocoagulation, during intervals between the treatment sittings, within 36 h of the final treatment and 4 months after its conclusion. Treatments were carried out with blue-green argon (eight eyes) and red krypton (eight eyes) lasers; the type of laser was randomly chosen. The analysis of the results obtained showed a significant and marked reduction in peak amplitudes of both a- and b-waves in photopic and dark-adapted conditions as early as between the multiple treatments. Electroretinograph (ERG) tracks did not change significantly at subsequent checks. Amplitude reductions were higher for scotopic b-waves and in eyes that had the less altered baseline tracks. Implicit times did not change significantly. The type of laser used did not significantly influence ERG evolution.
authors.affiliation: Department of Ophthalmology, San Raffaele Hospital, University of Milan, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Capoferri
authors.forename: M
authors.initials: M
authors.lastname: Bagini
authors.forename: A
authors.initials: A
authors.lastname: Chizzoli
authors.forename: A
authors.initials: A
authors.lastname: Pece
authors.forename: R
authors.initials: R
authors.lastname: Brancato
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D001128:Argon; D003623:Dark Adaptation; D003930:Diabetic Retinopathy / Q000601:surgery*; D004596:Electroretinography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007726:Krypton; D008028:Light Coagulation / Q000379:methods; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011897:Random Allocation; D014792:Visual Acuity
chemical_list: D007726:Krypton; D001128:Argon