Activity of 2-acetylaminofluorene as a UDS inducing agent in B6C3F1 mouse hepatocytes in vitro.
2-Acetylaminofluorene (2AAF) is shown to be reproducibly active in inducing UDS in cultured hepatocytes from a B6C3F1 mouse liver.
Lefevre
P A
PA
ICI Central Toxicology Laboratory, Macclesfield, Cheshire.
Ashby
J
J
D015073:2-Acetylaminofluorene / Q000494:pharmacology* / Q000633:toxicity; D000818:Animals; D002478:Cells, Cultured; D004247:DNA / Q000096:biosynthesis* / Q000378:metabolism; D004261:DNA Replication / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D008099:Liver / Q000166:cytology* / Q000187:drug effects / Q000378:metabolism; D008297:Male; D051379:Mice
D004247:DNA; D015073:2-Acetylaminofluorene