title: A distinctive neurologic syndrome after induced profound hypothermia.
abstract: Four patients suffered a distinctive neurologic syndrome after undergoing profound hypothermia and complete circulatory arrest for congenital heart lesion repair. Symptom onset was delayed 24-120 hours postoperatively. The syndrome consists of choreoathetosis and oral-facial dyskinesias, hypotonia, affective changes, and pseudobulbar signs (CHAP). Precise anatomic localization is uncertain. Magnetic resonance imaging of 2 patients did not reveal basal ganglia lesions. Pathogenesis is obscure.
authors.affiliation: Department of Neurology, University of New Mexico School of Medicine, Albuquerque 87131.
authors.forename: B S
authors.initials: BS
authors.lastname: Wical
authors.forename: L G
authors.initials: LG
authors.lastname: Tomasi
mesh_terms: D001264:Athetosis / Q000209:etiology*; D001794:Blood Pressure; D002675:Child, Preschool; D002819:Chorea / Q000209:etiology*; D005145:Face; D005260:Female; D006330:Heart Defects, Congenital / Q000601:surgery*; D006801:Humans; D007036:Hypothermia, Induced / Q000009:adverse effects*; D007223:Infant; D008297:Male; D019964:Mood Disorders / Q000209:etiology; D009069:Movement Disorders / Q000209:etiology*; D010243:Paralysis / Q000209:etiology; D011183:Postoperative Complications / Q000209:etiology*; D013577:Syndrome