[Evaluation of the clinical significance of determining the level of plasma fibronectin in acute poisoning].
Changes in plasma fibronectin (FN) levels in acute toxic conditions have been studied in 24 patients. A significant reduction of FN concentration was found within the first days of the disease; further changes in the FN levels are related to the disease outcome and have a prognostic value. An inverse correlation was found between the FN concentration and other blood biochemical parameters (LDH, creatinine, and urea). Developed renal insufficiency in the presence of hypofibronectinemia suggests a poor prognosis of the disease.
Shimanko
I I
II
Nazarenko
A A
AA
Osmanov
S K
SK
Tsepliaeva
G I
GI
Kuz'mina
N S
NS
Lebedeva
Iu N
IuN
Zimina
L N
LN
D000208:Acute Disease; D005353:Fibronectins / Q000097:blood*; D006801:Humans; D011041:Poisoning / Q000097:blood*; D011379:Prognosis
D005353:Fibronectins
Otsenka klinicheskoĭ znachimosti opredeleniia urovnia plazmennogo fibronektina pri ostrykh toksicheskikh porazheniiakh.