title: Quantitative static secondary ion mass spectrometry of molecular ions from 1-beta-3,4-dihydroxyphenylalanine (L-dopa) and indolic derivatives.
abstract: Traditionally, static secondary ion mass spectrometry (SIMS) is believed to yield qualitative information and very little quantitative information. A method to obtain quantitative molecular ion data from organic static SIMS analysis of L-DOPA and related compounds is presented. Linear calibration curves have been constructed by integrating the protonated molecular ion to silver ion peak area ratios over a known ion dosage and plotting versus the original sample concentration.
authors.affiliation: Department of Chemistry, State University of New York, Buffalo 14214.
authors.forename: M B
authors.initials: MB
authors.lastname: Clark
authors.forename: J A
authors.initials: JA
authors.lastname: Gardella
mesh_terms: D007477:Ions; D007980:Levodopa / Q000032:analysis*; D013058:Mass Spectrometry / Q000379:methods
chemical_list: D007477:Ions; D007980:Levodopa