title: Increased concentrations of D-dimers in newborn infants.
abstract: The concentrations of D-dimers (the D fragments of fibrinogen) were measured in blood from 15 preterm infants, and 45 born at full term, to establish normal ranges. The adult normal range is less than 0.25 mg/l; 31 of the 60 infants (52%) had values less than 0.25 mg/l, in 16 (27%) they were 0.25-0.5, in eight (13%) 0.5-1, in three (5%) 1-2, and in two (3%) 2-4. D-dimer concentrations measured during the neonatal period should be interpreted with caution.
authors.affiliation: Royal Hospital for Sick Children, Yorkhill, Glasgow.
authors.forename: I R
authors.initials: IR
authors.lastname: Hudson
authors.forename: B E
authors.initials: BE
authors.lastname: Gibson
authors.forename: J
authors.initials: J
authors.lastname: Brownlie
authors.forename: B M
authors.initials: BM
authors.lastname: Holland
authors.forename: T L
authors.initials: TL
authors.lastname: Turner
authors.forename: R G
authors.initials: RG
authors.lastname: Webber
mesh_terms: D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D006801:Humans; D007231:Infant, Newborn / Q000097:blood*; D007234:Infant, Premature / Q000097:blood; D012016:Reference Values
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; C015214:fibrinogen D fragment