title: Epiglottic augmentation in the horse.
abstract: Epiglottic augmentation with injectable bovine collagen or an autogenous or allogenous auricular cartilage graft was performed in 12 horses with endoscopically and radiographically normal epiglottises. The grafting procedures were easy to perform and did not cause apparent discomfort. Cartilage graft extrusion or resorption may have occurred, but was not seen by endoscopy and lateral laryngeal radiography. Only collagen implants remained evident endoscopically, as smooth round submucosal bulges ventral to the epiglottic cartilage. Two horses with collagen implants, and all horses with cartilage autografts and allografts, were euthanatized at week 16. One horse with a collagen implant was euthanatized at week 4 and one at week 6. The epiglottis appeared thickened in three horses with collagen implants, two horses with autogenous grafts, and three horses with allogenous grafts. Pharyngeal lymphoid tissue was hyperplastic in two horses with autografts and three horses with allografts, but not in horses with collagen implants. Collagen grafts persisted as one or two smooth bulges 8 mm in diameter. Collagen incited a brisk foreign body reaction that was surrounded by a fibrous connective tissue capsule. Epiglottises of the horses with collagen implants were significantly thicker 20 mm from the tip than those of normal horses and horses with allografts. Cartilage graft incorporation was not evident grossly and was seen on microscopic examination in only one autograft. Thickening was caused by submucosal fibrosis.
authors.affiliation: Department of Clinical Studies, University of Pennsylvania, School of Veterinary Medicine, Kennett Square.
authors.forename: E
authors.initials: E
authors.lastname: Tulleners
authors.forename: P
authors.initials: P
authors.lastname: Mann
authors.forename: C W
authors.initials: CW
authors.lastname: Raker
mesh_terms: D000818:Animals; D002356:Cartilage / Q000637:transplantation*; D003094:Collagen; D004423:Ear; D004825:Epiglottis / Q000033:anatomy & histology / Q000601:surgery*; D005260:Female; D006736:Horses / Q000601:surgery*; D007828:Laryngoscopy / Q000662:veterinary; D008297:Male; D011182:Postoperative Care / Q000662:veterinary; D019736:Prostheses and Implants / Q000662:veterinary*; D014182:Transplantation, Autologous / Q000662:veterinary; D014184:Transplantation, Homologous / Q000662:veterinary
chemical_list: D003094:Collagen