title: [Treatment of severe hepatic insufficiency by perfusion of patients' blood through a suspension of cryopreserved hepatocytes].
abstract: The results of hemoperfusion through a suspension of cryoconserved hepatocytes in 21 patients with severe hepatic insufficiency are analysed. It is shown that the manipulation had a beneficial effect on the clinical and biochemical indices, which was manifested by diminished jaundice and skin pruritus, increased physical activity, improved appetite; reduced levels of bilirubin, transaminase, alkaline phosphatase, bile acids, and cholesterol. The information gained is evidence that the method can be included in the complex treatment of patients with severe hepatic insufficiency.
authors.forename: V I
authors.initials: VI
authors.lastname: Shumakov
authors.forename: V S
authors.initials: VS
authors.lastname: Arzumanov
authors.forename: N A
authors.initials: NA
authors.lastname: Onishchenko
authors.forename: A V
authors.initials: AV
authors.lastname: Sechkin
authors.forename: M A
authors.initials: MA
authors.lastname: Danilov
authors.forename: N K
authors.initials: NK
authors.lastname: Shestakova
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Toshchakov
mesh_terms: D000328:Adult; D000818:Animals; D015925:Cryopreservation; D005260:Female; D006464:Hemoperfusion / Q000379:methods*; D006501:Hepatic Encephalopathy / Q000628:therapy*; D006801:Humans; D066298:In Vitro Techniques; D008099:Liver / Q000166:cytology; D008297:Male; D008875:Middle Aged; D013535:Suspensions; D013552:Swine; D014019:Tissue Donors
chemical_list: D013535:Suspensions
vernacular_title: Lechenie tiazheloĭ pechenochnoĭ nedostatochnosti perfuzieĭ krovi bol'nogo cherez vzves' kriokonservirovannykh gepatotsitov.