Hereditary sensory neuropathy type II without trophic changes.
Three cases with sensory peripheral neuropathies are reported. Case 1 presented with scoliosis, and cases 2 and 3 presented with abnormal gait. None had trophic limb changes, evidence of weakness, or a tendency to self-mutilation and each had normal motor studies on neurophysiological testing. Sural nerve biopsies showed a severe loss of myelinated fibres and case 3 had evidence of denervation on muscle biopsy. These cases are presented as examples of hereditary sensory neuropathy type II. They are unusual in that they do not have trophic changes.
Bye
A M
AM
Department of Neurology, Prince of Wales Children's Hospital, Randwick, N.S.W., Australia.
Baker
W D
WD
Pollard
J
J
Wise
G
G
D000293:Adolescent; D002675:Child, Preschool; D005260:Female; D009477:Hereditary Sensory and Autonomic Neuropathies / Q000503:physiopathology*; D006801:Humans; D008297:Male; D009431:Neural Conduction