title: An evaluation of 99mTc-HMPAO uptake in cerebral gliomas--a comparison with X-ray CT.
abstract: Nineteen patients with biopsy-proven cerebral gliomas were studied with 99mTc-HMPAO single photon emission tomography (SPECT) imaging and X-ray computed tomography (CT). The uptake of 99mTc-HMPAO was correlated with tumour size and morphology as shown by X-ray CT, and overall patient survival. It appears that uptake of 99mTc-HMPAO is associated with larger, ill-defined tumours and was an adverse factor in patient survival. In those tumours with normal or increased uptake, 99mTc-HMPAO imaging is useful in distinguishing the tumour margin from surrounding oedema.
authors.affiliation: Department of Nuclear Medicine, Royal Marsden Hospital, Sutton, Surrey, UK.
authors.forename: A T
authors.initials: AT
authors.lastname: Irvine
authors.forename: M A
authors.initials: MA
authors.lastname: Flower
authors.forename: R J
authors.initials: RJ
authors.lastname: Ott
authors.forename: J W
authors.initials: JW
authors.lastname: Babich
authors.forename: F
authors.initials: F
authors.lastname: Kabir
authors.forename: V R
authors.initials: VR
authors.lastname: McCready
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging*; D005910:Glioma / Q000000981:diagnostic imaging*; D006801:Humans; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime