Sick sinus syndrome as a complication of mediastinal radiation therapy.
A 33-year-old man who had received mediastinal radiation therapy for Hodgkin's disease 12 years earlier developed a symptomatic sick sinus syndrome requiring the implantation of a permanent pacemaker. The sick sinus syndrome and a finding of an occult constrictive pericarditis were considered to be due to the previous mediastinal irradiation. A ventricular pacemaker was chosen because mediastinal radiotherapy also increases the risk of developing atrioventricular conduction defects.
Pohjola-Sintonen
S
S
First Department of Medicine, Helsinki University Central Hospital, Finland.
Tötterman
K J
KJ
Kupari
M
M
D000328:Adult; D006689:Hodgkin Disease / Q000532:radiotherapy; D006801:Humans; D008297:Male; D008482:Mediastinum / Q000528:radiation effects*; D011878:Radiotherapy / Q000009:adverse effects*; D012804:Sick Sinus Syndrome / Q000209:etiology*