title: Prechemotherapy dental treatment to prevent bacteremia.
abstract: Infection is the most common cause of morbidity and death in patients receiving chemotherapy for treatment of acute leukemia. Studies performed during the past decade suggest that over 30% of these infections originate from oral sources, particularly periodontal pockets and pericoronal flaps. Studies of large numbers of patients receiving a variety of myelosuppressive chemotherapy protocols are necessary to determine the risk-benefit ratio of dental treatment prior to chemotherapy.
authors.affiliation: University of Pennsylvania School of Dental Medicine, Philadelphia.
authors.forename: M S
authors.initials: MS
authors.lastname: Greenberg
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007938:Leukemia / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology; D018805:Sepsis / Q000209:etiology / Q000517:prevention & control*; D014076:Tooth Diseases / Q000150:complications / Q000628:therapy*
chemical_list: D000970:Antineoplastic Agents