Tourette-like disorder in Asperger's syndrome.
An eight-year-old boy with Asperger's syndrome was given haloperidol to control agitation and aggressive outbursts. Withdrawal of the drug after two years was followed by Tourette-like symptoms. Subsequently neither haloperidol nor a second antipsychotic drug altered the core features of Asperger's syndrome, despite suppressing the movement disorder. His first exposure to neuroleptics was in utero.
Littlejohns
C S
CS
North Wales Hospital, Denbigh.
Clarke
D J
DJ
Corbett
J A
JA
D000293:Adolescent; D001321:Autistic Disorder / Q000188:drug therapy*; D005260:Female; D006220:Haloperidol / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D005879:Tourette Syndrome / Q000209:etiology*
D006220:Haloperidol