title: [Properties of glucose-6-phosphate dehydrogenase of the liver tissue of intact rats and rats with Zaidel ascitic hepatoma].
abstract: The properties of glucose-6-phosphate dehydrogenase (G6PDH; glucose-6-phosphate-NADP-oxidoreductase, EC 1.1.1.49) in the liver tissue of intact rats and those with ascites Zaidel hepatoma were compared. The specific activity of the enzyme from hepatoma was 7 times as high as that of the enzyme from the normal liver. The G6PDH preparations with the specific activity of 1.5 U/mg of protein were obtained by the three-stage purification. No differences in kinetic properties, coenzyme specificity and electrophoretic mobility of the enzymes from hepatoma and normal liver were observed.
authors.forename: L S
authors.initials: LS
authors.lastname: Chesnokova
mesh_terms: D000818:Animals; D004586:Electrophoresis; D005954:Glucosephosphate Dehydrogenase / Q000032:analysis*; D008099:Liver / Q000032:analysis*; D008114:Liver Neoplasms, Experimental / Q000032:analysis / Q000201:enzymology*; D008297:Male; D051381:Rats
chemical_list: D005954:Glucosephosphate Dehydrogenase
vernacular_title: Svoĭstva gliukozo-6-fosfatdegidrogenazy tkaneĭ pecheni intaktnykh krys i krys s astsitnoĭ gepatomoĭ Zaĭdela.