[Blood coagulating properties of the copperhead Agkisrodon halys halys venom and its thrombin-like fractions].
Venom and its fraction with hemocoagulation properties from Agkistrodon halys halys exhibited dissimilar effects on blood plasma and fibrinogen preparation. The major component of this fraction proved to be a thrombin-like enzyme, properties of which were studied by means of several coagulation tests. Dissimilarity in coagulating effects of the venom and its thrombin-like fraction as well as different physical properties of blood clots formed after their action suggest that the venom from Agkistrodon halys halys contained other protein factors affecting blood coagulation besides the thrombin-like proteases.
Kalmykova
I B
IB
Zaĭchenko
O B
OB
Sadykov
E S
ES
Barabanshchikova
N A
NA
Iukel'son
L Ia
LIa
D001777:Blood Coagulation / Q000187:drug effects*; D001780:Blood Coagulation Tests; D003435:Crotalid Venoms / Q000032:analysis / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D013917:Thrombin / Q000302:isolation & purification / Q000494:pharmacology*
D003435:Crotalid Venoms; D013917:Thrombin
Gemokoaguliatsionnaia kharakteristika iada shchitomordika Agkistrodon halys halys i ego trombinopodobnoĭ fraktsii.