Concomitant allergic Aspergillus sinusitis and allergic bronchopulmonary aspergillosis associated with familial occurrence of allergic bronchopulmonary aspergillosis.
A 24-year-old male, who had nasal symptoms with occasional wheezing was evaluated for consolidation of the right lung which led to the diagnosis of concomitant allergic Aspergillus sinusitis (AAS) and allergic bronchopulmonary aspergillosis (ABPA), a rarely reported association. The patient's mother was a diagnosed case of ABPA. Dramatic relief of nasal and pulmonary symptoms resulted with prednisolone that could not be tapered off completely. No untoward effect of prednisolone was observed on the disease process in a follow-up of 2 years. A high index of suspicion is required for the diagnosis of AAS and family members with history of asthma and/or rhinitis should be investigated for ABPA and/or AAS.
Shah
A
A
Department of Clinical Research, University of Delhi, India.
Khan
Z U
ZU
Chaturvedi
S
S
Malik
G B
GB
Randhawa
H S
HS
D000328:Adult; D001228:Aspergillosis / Q000150:complications* / Q000628:therapy; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000150:complications* / Q000235:genetics / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012852:Sinusitis / Q000150:complications* / Q000628:therapy