title: Melanoma as a cause of spinal cord compression in two horses.
abstract: Spinal cord compression by melanomas at C7-T1 is described in 2 horses. Despite similar location of the lesions, the onset of neurologic signs and clinical progression varied. Both horses were gray, but few cutaneous melanomas were found. Internal dissemination, however, was extensive in both horses. Antemortem diagnosis was made in one horse, and surgical decompression of the spinal cord was performed. Neoplasms of the vertebral canal and spinal cord are uncommon in horses. Melanoma in the spinal canal should be included in the differential diagnosis of neurologic disease, especially in mature gray horses.
authors.affiliation: Department of Veterinary Clinical Medicine and Surgery, Washington State University, Pullman 99164-6610.
authors.forename: H C
authors.initials: HC
authors.lastname: Schott
authors.forename: M D
authors.initials: MD
authors.lastname: Major
authors.forename: B D
authors.initials: BD
authors.lastname: Grant
authors.forename: W M
authors.initials: WM
authors.lastname: Bayly
mesh_terms: D000818:Animals; D005260:Female; D006734:Horse Diseases / Q000209:etiology*; D006736:Horses; D008297:Male; D008545:Melanoma / Q000150:complications / Q000662:veterinary*; D009192:Myelography / Q000662:veterinary; D013117:Spinal Cord Compression / Q000209:etiology / Q000662:veterinary*; D013120:Spinal Cord Neoplasms / Q000150:complications / Q000662:veterinary*