Quantitative static secondary ion mass spectrometry of molecular ions from 1-beta-3,4-dihydroxyphenylalanine (L-dopa) and indolic derivatives.
Traditionally, static secondary ion mass spectrometry (SIMS) is believed to yield qualitative information and very little quantitative information. A method to obtain quantitative molecular ion data from organic static SIMS analysis of L-DOPA and related compounds is presented. Linear calibration curves have been constructed by integrating the protonated molecular ion to silver ion peak area ratios over a known ion dosage and plotting versus the original sample concentration.
Clark
M B
MB
Department of Chemistry, State University of New York, Buffalo 14214.
Gardella
J A
JA
D007477:Ions; D007980:Levodopa / Q000032:analysis*; D013058:Mass Spectrometry / Q000379:methods
D007477:Ions; D007980:Levodopa