title: Retained trophoblast after conservative management of ectopic pregnancy. A report of two cases.
abstract: With the advent of conservative management of ectopic gestation, several patients have had persistent trophoblastic tissue after their surgical procedure. In the past such patients required repeat laparoscopy or laparotomy and further conservative or radical surgery. However, the use of methotrexate with leukovorum rescue offers a new alternative in the management of patients with persistent trophoblastic tissue after conservative surgery. Two patients with persistent trophoblastic tissue were treated successfully with methotrexate and leukovorum rescue. The use of medical therapy in such patients avoids a second surgical procedure, is associated with few side effects and appears to be an acceptable management alternative.
authors.affiliation: Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee 37232.
authors.forename: G A
authors.initials: GA
authors.lastname: Hill
authors.forename: P S
authors.initials: PS
authors.lastname: Cartwright
authors.forename: C M
authors.initials: CM
authors.lastname: Herbert
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use; D008727:Methotrexate / Q000008:administration & dosage; D011183:Postoperative Complications; D011247:Pregnancy; D011274:Pregnancy, Tubal / Q000601:surgery*; D014327:Trophoblasts
chemical_list: D002955:Leucovorin; D008727:Methotrexate