[Inhibitors of the nitrite oxidation of hemoglobin].
Different types of active inhibitors of the reaction of nitrite hemoglobin oxidation have been revealed and studied. The dependence of inhibition of methemoglobin formation, on concentration of inhibitors at pH 5.9 and 7.17 has been determined. Differential absorption spectra of the inhibitors in the presence sodium nitrite in UV and visual light has been studied. The values of oxidation-reduction potentials have been estimated. Possible mechanism of action of the inhibitors has been discussed.
Kostenko
L Kh
LKh
Rozantsev
E G
EG
Ozhogina
O A
OA
D000818:Animals; D002417:Cattle; D003864:Depression, Chemical; D006454:Hemoglobins / Q000187:drug effects* / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D008706:Methemoglobin / Q000187:drug effects / Q000378:metabolism; D009573:Nitrites / Q000037:antagonists & inhibitors*; D010084:Oxidation-Reduction / Q000187:drug effects
D006454:Hemoglobins; D009573:Nitrites; D008706:Methemoglobin
Ingibitory nitritnogo okisleniia gemoglobina.