title: Hyperthyroidism during pregnancy due to coexistence of struma ovarii and Graves' disease.
abstract: A patient with hyperthyroid Graves' disease and struma ovarii is described. She had pre-existing Graves' disease and positive thyrotrophin receptor antibody. She was treated with radioactive iodine 5 months before she became pregnant. Paripartum she had torsion of an ovarian cyst with histological evidence of a functional struma ovarii. Immediate exacerbation of her thyrotoxic state was observed after operation as a result of release of thyroid hormone from the tumour. It is postulated that the tumour was stimulated by circulating thyrotrophin receptor antibody.
authors.affiliation: Department of Medicine, University of Hong Kong, Queen Mary Hospital.
authors.forename: A W
authors.initials: AW
authors.lastname: Kung
authors.forename: J T
authors.initials: JT
authors.lastname: Ma
authors.forename: C
authors.initials: C
authors.lastname: Wang
authors.forename: R T
authors.initials: RT
authors.lastname: Young
mesh_terms: D000328:Adult; D000906:Antibodies / Q000032:analysis; D005260:Female; D006111:Graves Disease / Q000150:complications* / Q000532:radiotherapy; D006801:Humans; D006980:Hyperthyroidism / Q000209:etiology*; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D010051:Ovarian Neoplasms / Q000150:complications*; D011247:Pregnancy; D011248:Pregnancy Complications; D011252:Pregnancy Complications, Neoplastic; D011989:Receptors, Thyrotropin / Q000276:immunology; D013330:Struma Ovarii / Q000150:complications*
chemical_list: D000906:Antibodies; D007457:Iodine Radioisotopes; D011989:Receptors, Thyrotropin