[The effect of contrasting fat diets on the cholesterol-esterifying activity of the blood plasma].
The blood plasma cholesterol (CS) level increased by 170% due CS of atherogenic lipoproteins (LP) in dogs that received atherogenic rations including lamb fat (LF) (group 1) during 2 months. In dogs of group 2 that received atherogenic rations including sunflower oil (SFO), the total content of CS in the blood plasma rose only by 50%, the portion of high density LP (HDLP) decreased from 73 to 25% in both groups of animals. LF and SFO produced no effect on the plasma CS level, when the dogs did not receive excessive CS in the ration (groups 3 and 4). SFO induced reduction in the rate of the lecitin-cholesterolacyltransferase (LCAT) reaction, both in normal and excessive CS consumption. Nevertheless, the ratio free CS/CS esters was lowered that denoted the appearance in the blood of CS esters, the nature of which was not associated with the LCAT reaction. In the animals of groups 1, 2 and 3 the share of oleic acid in phosphatidylcholine of HDLP increased (in group 3 this increase was most manifest), while the portion of stearic acid significantly diminished.
Akhmetov
B S
BS
Nikitin
B N
BN
Dukravets
N A
NA
D000818:Animals; D002784:Cholesterol / Q000097:blood; D002788:Cholesterol Esters / Q000097:blood*; D004036:Diet, Atherogenic; D004041:Dietary Fats / Q000008:administration & dosage*; D004042:Dietary Fats, Unsaturated / Q000008:administration & dosage*; D004285:Dogs; D006937:Hypercholesterolemia / Q000097:blood / Q000178:diet therapy / Q000209:etiology; D008055:Lipids / Q000097:blood; D008075:Lipoproteins, HDL / Q000097:blood; D008297:Male; D007862:Phosphatidylcholine-Sterol O-Acyltransferase / Q000097:blood
D002788:Cholesterol Esters; D004041:Dietary Fats; D004042:Dietary Fats, Unsaturated; D008055:Lipids; D008075:Lipoproteins, HDL; D002784:Cholesterol; D007862:Phosphatidylcholine-Sterol O-Acyltransferase
Vliianie kontrastnykh zhirovykh diet na kholesterinésterifitsiruiushchuiu aktivnost' plazmy krovi.