title: [A polypoidal adenosquamous cell carcinoma of the esophagus with a pseudosarcomatous stromal reaction].
abstract: A case of a polypoidal carcinoma with a pseudosarcomatous stromal reaction is presented. Histologically, the polypoidal tumor of the lower esophagus was revealed to be an adenosquamous cell carcinoma associated with the proliferation of atypical stromal cells, osteoclastic-like giant cells, and histiocytes. Using an immunohistochemical stain, these stromal atypical cells were found to be positive for vimentin, with some cells positive for alpha 1-antichymotrypsin. However these atypical cells proved negative as epithelial markers (keratin and EMA). Thus, it was felt that such atypical stromal cells may be a reactive proliferation of the stromal cells to an adenosquamous cell carcinoma.
authors.affiliation: Dept. of Pathology, Shimonoseki City Hospital.
authors.forename: A
authors.initials: A
authors.lastname: Tanimura
authors.forename: K
authors.initials: K
authors.lastname: Yatsuka
authors.forename: R
authors.initials: R
authors.lastname: Sakai
authors.forename: K
authors.initials: K
authors.lastname: Tachibana
authors.forename: S
authors.initials: S
authors.lastname: Noda
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000473:pathology*; D005350:Fibroma / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D014746:Vimentin / Q000032:analysis; D000514:alpha 1-Antichymotrypsin / Q000032:analysis
chemical_list: D014746:Vimentin; D000514:alpha 1-Antichymotrypsin