title: [IgA-nephropathy in childhood].
abstract: IgA nephropathy or M. Berger is regularly diagnosed in childhood. A kidney biopsy is necessary to verify the diagnosis, by demonstrating deposition of IgA in the glomerular mesangium. The kidney biopsy is performed in cases of recurrent macroscopic haematuria or persistence of microscopic haematuria, with or without proteinuria. The prognosis and factors influencing the prognosis in childhood IgA nephropathy are uncertain. In a mainly retrospective study we tried to find correlations between clinical and histological findings and the outcome after a mean follow up period of 7.36 years in 56 patients. In this study with its restrictions it was impossible to find correlations between histological parameters and outcome on one side and between sex, hypertension, macroscopic c.q. microscopic haematuria, proteinuria and outcome on the other hand.
authors.affiliation: Instituut voor Kindergeneeskunde, Academisch Ziekenhuis Nijmegen.
authors.forename: M C
authors.initials: MC
authors.lastname: de Jong
authors.forename: C M
authors.initials: CM
authors.lastname: van Dael
authors.forename: B
authors.initials: B
authors.lastname: van Damme
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D005922:Glomerulonephritis, IGA / Q000150:complications / Q000453:epidemiology* / Q000473:pathology; D006417:Hematuria / Q000209:etiology; D006801:Humans; D007070:Immunoglobulin A / Q000302:isolation & purification; D007677:Kidney Function Tests; D007678:Kidney Glomerulus / Q000473:pathology; D008297:Male; D009426:Netherlands / Q000453:epidemiology; D011446:Prospective Studies
chemical_list: D007070:Immunoglobulin A
vernacular_title: IgA-nefropathie op de kinderleeftijd.