[Locally advanced breast cancer--primary treatment with tamoxifen].
Tamoxifen was given as primary systemic treatment to 28 patients with locally advanced breast cancer. In all tumours, receptors for estrogen (ER) and/or progesterone (PGR) were positive. All patients (15) with high levels of hormone receptors (ER greater than or equal to 100 mumols/g protein and/or PGR greater than or equal to 200 mumols/g protein) were alive after two years of observation as against 60% of the patients (13) with lower hormone receptor values.
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Avdeling for medisinsk onkologi Det Norske Radiumhospital, Oslo.
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Fosså
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Gundersen
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D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000378:metabolism; D005260:Female; D006801:Humans; D008875:Middle Aged; D013629:Tamoxifen / Q000627:therapeutic use*
D013629:Tamoxifen
Lokalavansert brystkreft--primaerbehandling med tamoxifen.