title: Variation in virulence among oculogenital serovars of Chlamydia trachomatis in experimental genital tract infection.
abstract: Seven different oculogenital serovars (D, E, F, G, H, I, and K) of Chlamydia trachomatis were inoculated intravaginally into CF-1 mice, and subsequent infection was monitored. The duration of infection was longest with serovars D and E. This may help to explain clinical surveys which demonstrate a high (50%) prevalence of these serovars. Furthermore, a comparison of the invasiveness of strains D and H demonstrated a much higher frequency of uterine horn infection with serovar D.
authors.affiliation: Department of Infectious Diseases, City of Hope National Medical Center, Duarte, California 91010.
authors.forename: J I
authors.initials: JI
authors.lastname: Ito
authors.forename: J M
authors.initials: JM
authors.lastname: Lyons
authors.forename: L P
authors.initials: LP
authors.lastname: Airo-Brown
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D002690:Chlamydia Infections / Q000382:microbiology*; D002692:Chlamydia trachomatis / Q000145:classification / Q000276:immunology / Q000472:pathogenicity*; D005260:Female; D005831:Genital Diseases, Female / Q000382:microbiology*; D051379:Mice; D012703:Serotyping; D014621:Vagina / Q000382:microbiology
chemical_list: D000907:Antibodies, Bacterial