title: Characteristics of a cell line established from a Chinese patient with a squamous carcinoma of the uterine cervix.
abstract: A new cell line, CC3/CUHK3, was established from a squamous carcinoma of the uterine cervix from a Chinese patient. Light microscopy of the cell line revealed keratin and electron microscopy demonstrated tonofilaments and desmosomes, thereby confirming its epithelial nature. The population doubling time of CC3/CUHK3, estimated from the exponential growth phase of the growth curve established from the cell line was 42 hours. When the tumour cells were inoculated into athymic mouse, a tumour, microscopically diagnosed as a well-differentiated carcinoma, developed. These cells are highly invasive in vitro.
authors.affiliation: Department of Anatomy, Faculty of Medicine, The Chinese University of Hong Kong.
authors.forename: E C
authors.initials: EC
authors.lastname: Chew
authors.forename: T H
authors.initials: TH
authors.lastname: Ho
authors.forename: S O
authors.initials: SO
authors.lastname: Yeung
authors.forename: H J
authors.initials: HJ
authors.lastname: Hou
authors.forename: R S
authors.initials: RS
authors.lastname: Li
authors.forename: D P
authors.initials: DP
authors.lastname: Huang
authors.forename: F W
authors.initials: FW
authors.lastname: Wong
mesh_terms: D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000235:genetics / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D051379:Mice; D014407:Tumor Cells, Cultured; D002583:Uterine Cervical Neoplasms / Q000235:genetics / Q000473:pathology* / Q000648:ultrastructure