Effect of copperglycinate on the radiation induced micronuclei formation in mice bone marrow.
The frequency of micronuclei were determined in the bone marrow of Swiss albino mice treated with or without copperglycinate 15 min before exposure to 4.5 Gy gamma radiation. The frequency of micronuclei increased from day 1/4 to day 1 post-irradiation in both the irradiated groups and declined thereafter, with the frequency of micronuclei remaining significantly lower in the copperglycinate treated animals.
Jagetia
G C
GC
Department of Radiobiology, Kasturba Medical College, Karnataka, India.
Ganapathi
N G
NG
D000818:Animals; D001853:Bone Marrow / Q000528:radiation effects*; D003300:Copper / Q000494:pharmacology*; D005998:Glycine / Q000494:pharmacology*; D008297:Male; D051379:Mice; D048629:Micronuclei, Chromosome-Defective / Q000187:drug effects*; D009942:Organometallic Compounds / Q000494:pharmacology*; D011837:Radiation-Protective Agents / Q000494:pharmacology*
D009942:Organometallic Compounds; D011837:Radiation-Protective Agents; C018493:cupric glycinate; D003300:Copper; D005998:Glycine