title: Anterior temporal lobectomy and medically refractory temporal lobe epilepsy of childhood.
abstract: The evaluation and outcome of 22 patients who had onset of complex partial seizures (CPS) of temporal lobe origin in childhood and subsequently underwent anterior temporal lobectomy are described. All patients showed improved seizure control; 81.8% had a reduction greater than or equal to 95% in seizure frequency. However, many patients had difficulty adjusting to a seizure-free life. Psychosocial, behavioral, and educational problems occurred more frequently in patients whose surgery was delayed until adult life. We conclude that attempts should be made early in the course of CPS of childhood to determine whether the seizures are truly intractable to medical management so that surgical intervention can be expedited.
authors.affiliation: Department of Neurology, Baylor College of Medicine, Houston, TX 77030.
authors.forename: E M
authors.initials: EM
authors.lastname: Mizrahi
authors.forename: P
authors.initials: P
authors.lastname: Kellaway
authors.forename: R G
authors.initials: RG
authors.lastname: Grossman
authors.forename: P A
authors.initials: PA
authors.lastname: Rutecki
authors.forename: D
authors.initials: D
authors.lastname: Armstrong
authors.forename: G
authors.initials: G
authors.lastname: Rettig
authors.forename: S
authors.initials: S
authors.lastname: Loewen
mesh_terms: D000223:Adaptation, Psychological; D002540:Cerebral Cortex / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D004493:Education; D004569:Electroencephalography; D004827:Epilepsy / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D005260:Female; D006801:Humans; D007802:Language; D008297:Male; D008568:Memory; D009420:Nervous System / Q000503:physiopathology; D009790:Occupations; D011184:Postoperative Period; D013702:Temporal Lobe / Q000601:surgery*; D014057:Tomography, X-Ray Computed