Relationship between body fat distribution and blood lipids in obese adolescents.
Associations between body fat distribution, measured by waist/hip circumference ratio (WHR), and plasma lipids and lipoproteins were examined in 74 grossly obese adolescents. WHR was positively correlated in adolescent girls with total triglycerides (r = 0.44, P less than 0.01), total cholesterol (r = 0.49, P less than 0.001), and LDL-cholesterol (r = 0.59, P less than 0.001). In adolescent boys no correlation was found for total cholesterol but there were correlations for triglycerides (r = 0.41, P less than 0.05), LDL-cholesterol (r = 0.49, P less than 0.001), HDL-cholesterol (r = -0.66, P less than 0.001) and the ratio cholesterol/HDL-cholesterol (r = 0.62, P less than 0.001). Waist/hip ratio was not correlated with BMI or percentual overweight in obese girls, but a significant association was found in obese boys for both (r = -0.46, P less than 0.03 and r = 0.53, P less than 0.02). These results indicate that in obese girls a prevalence of abdominal fat distribution is correlated with increased triglycerides, serum cholesterol and LDL-C. In male adolescents total cholesterol is only slightly influenced but HDL-C concentrations are lower and LDL-C and the ratio CHOL/HDL-C higher.
Zwiauer
K
K
Department of Pediatrics, University of Vienna, Austria.
Widhalm
K
K
Kerbl
B
B
D000273:Adipose Tissue / Q000473:pathology*; D000293:Adolescent; D000704:Analysis of Variance; D001827:Body Height; D015992:Body Mass Index; D001835:Body Weight; D002648:Child; D005260:Female; D006615:Hip; D006801:Humans; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood; D008297:Male; D009767:Obesity, Morbid / Q000097:blood / Q000473:pathology*
D008055:Lipids; D008074:Lipoproteins