title: Structural hair abnormalities in ectodermal dysplasia.
abstract: The hair of patients with three ectodermal dysplasias--ectrodactyly ectodermal dysplasia clefting syndrome (EEC); orofacial-digital syndrome (OFD) type I; and anhidrotic ectodermal dysplasia syndrome (AED)--were studied by scanning electron microscopy. While no pathognomonic abnormalities were noted for each condition, hair shaft structural defects were evident in all patients studied. The EEC clefting syndrome and OFD I shared the most deforming defects, while AED had fewer.
authors.affiliation: Department of Dermatology, University of Illinois, Chicago, IL 60612.
authors.forename: G
authors.initials: G
authors.lastname: Micali
authors.forename: B
authors.initials: B
authors.lastname: Cook
authors.forename: I
authors.initials: I
authors.lastname: Blekys
authors.forename: L M
authors.initials: LM
authors.lastname: Solomon
mesh_terms: D000015:Abnormalities, Multiple / Q000473:pathology*; D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004476:Ectodermal Dysplasia / Q000473:pathology*; D005260:Female; D006197:Hair / Q000002:abnormalities* / Q000648:ultrastructure; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008855:Microscopy, Electron, Scanning