Influence of serum on in vitro digestion of Paracoccidioides brasiliensis by neutrophils.
Serum from patients with paracoccidioidomycosis (PARA) did not block digestive abilities of neutrophils (PMNs) from healthy individuals against Paracoccidioides brasiliensis. Conversely, serum from healthy donors did not enhance digestive capacities of PMNs from patients with PARA vis á vis the causative organism. We conclude that the specific digestive defect present in PMNs from patients with PARA is not mediated by serum factors.
Goihman-Yahr
M
M
Section of Immunology I, Central University of Venezuela, Caracas.
Bastardo de Albornoz
M C
MC
Istúriz
G
G
Viloria
N
N
Saavedra de Borges
N
N
Carrasquero
M
M
Avila-Millán
E
E
Guilarte
A
A
Pereira
J
J
de Gómez
M H
MH
D000328:Adult; D001790:Blood Physiological Phenomena; D002478:Cells, Cultured; D005260:Female; D006801:Humans; D008297:Male; D003904:Mitosporic Fungi / Q000276:immunology*; D009504:Neutrophils / Q000276:immunology*; D010228:Paracoccidioides / Q000276:immunology*; D010229:Paracoccidioidomycosis / Q000276:immunology*; D010587:Phagocytosis