The upstream sequence -537 to -278 is necessary for transcription of the human nucleolar antigen p120 gene.
Two cis-acting elements in the p120 gene play important roles in transcription; the region from -537 to -278 is necessary for initiation of transcription, and the region from -1426 to -1223 is necessary for efficient transcription. The distal element(s) which lies upstream of -278 is required for initiation of transcription.
Haidar
M A
MA
Department of Pharmacology, Baylor College of Medicine, Houston, Texas 77030.
Henning
D
D
Busch
H
H
D000941:Antigens / Q000235:genetics*; D001483:Base Sequence; D002466:Cell Nucleolus / Q000276:immunology; D002872:Chromosome Deletion; D005809:Genes, Regulator; D006801:Humans; D008969:Molecular Sequence Data; D009154:Mutation; D009687:Nuclear Proteins / Q000235:genetics*; D015345:Oligonucleotide Probes; D011401:Promoter Regions, Genetic; D015183:Restriction Mapping; D014157:Transcription Factors / Q000378:metabolism; D014158:Transcription, Genetic
D000941:Antigens; D009687:Nuclear Proteins; D015345:Oligonucleotide Probes; D014157:Transcription Factors