Long term follow-up after portacaval shunt and internal mammary coronary bypass graft in homozygous familial hypercholesterolemia: report of two cases.
Homozygous familial hypercholesterolemia (HFH) is characterized by a very shortened lifespan, mainly due to cardiac events, and by resistance to conventional lipid lowering therapies. Two patients are described for whom a combination of portacaval shunt and mammary coronary bypass graft were done with good long term success. A review of the actual forms of treatment of HFH is made. To the authors' knowledge, there is no report in the literature of this double surgical approach.
Reeves
F
F
Department of Medicine, Montreal Heart Institute, Quebec.
Gosselin
G
G
Hébert
Y
Y
Lambert
M
M
D000293:Adolescent; D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000601:surgery* / Q000628:therapy; D007387:Internal Mammary-Coronary Artery Anastomosis; D008297:Male; D011167:Portacaval Shunt, Surgical