[Immunization of rabbits with Lassa virus].
The parameters of humoral and cell-mediated immunity after inoculation of the infectious and inactivated antigen of Lassa virus to rabbits which are insusceptible to this infection were studied. Lassa virus antigen was demonstrated to induce synthesis of specific antibodies in rabbits the level of which was proportional to the dose of inoculation and the time of immunization. The results of leukocyte blastogenesis test and delayed type hypersensitivity test confirm the development of sensitization to inactivated Lassa virus in immune rabbits.
Orlova
S V
SV
Godneva
A T
AT
Ignat'ev
G M
GM
Bystrova
S I
SI
D000818:Animals; D000917:Antibody Formation; D001116:Arenaviridae / Q000276:immunology*; D007111:Immunity, Cellular; D007114:Immunization; D007836:Lassa virus / Q000276:immunology*; D011817:Rabbits
Immunizatsiia krolikov virusom Lassa.