title: [Estradiol binding and lipid metabolism in the plasma membrane of myometrial cells during tumor growth].
abstract: The study was concerned with evaluation of the parameters of specific binding of 17-beta-estradiol to myometrial plasma membrane in tumor growth versus lipid profile of the membrane and A2 and C phospholipase activity. Tumor growth was shown to involve an increase in the association constant of plasma membrane, changes in the lipid profile and activity of the enzymes. The role of these factors in myometrial carcinogenesis is discussed.
authors.forename: P V
authors.initials: PV
authors.lastname: Sergeev
authors.forename: E N
authors.initials: EN
authors.lastname: Mineeva
authors.forename: T V
authors.initials: TV
authors.lastname: Ukhina
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002462:Cell Membrane / Q000378:metabolism*; D004958:Estradiol / Q000378:metabolism*; D005260:Female; D006801:Humans; D008563:Membrane Lipids / Q000378:metabolism*; D008875:Middle Aged; D009215:Myometrium / Q000166:cytology / Q000378:metabolism* / Q000473:pathology; D010741:Phospholipases A / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism; D011959:Receptors, Estradiol / Q000378:metabolism; D010738:Type C Phospholipases / Q000378:metabolism; D014594:Uterine Neoplasms / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology
chemical_list: D008563:Membrane Lipids; D010743:Phospholipids; D011959:Receptors, Estradiol; D004958:Estradiol; D010741:Phospholipases A; D010738:Type C Phospholipases
vernacular_title: Sviazyvanie éstradiola i metabolizm lipidov v plazmaticheskikh membranakh kletok miometriia pri opukholevom roste.