title: [Questionable usefulness of the edrophonium test in the diagnosis of non-cardiac retrosternal pain].
abstract: Of 69 patients with non-cardiac chest pain, one third had abnormal esophageal motility as evidenced by basal esophageal manometry. 8 patients (12%) reported chest pain during a provocation test (edrophonium). While this pain seemed similar to the spontaneous chest pain described by 7 patients, it was not associated with manometric changes in 30% of these cases. The causal relationship between disorders of esophageal motility and non-cardiac chest pain has still to be confirmed, and caution must be exercised in interpreting edrophonium tests.
authors.affiliation: Département de médecine, Hôpital cantonal universitaire, Genève.
authors.forename: G
authors.initials: G
authors.lastname: Apollonio
authors.forename: J P
authors.initials: JP
authors.lastname: Dederding
authors.forename: R
authors.initials: R
authors.lastname: Bosson
authors.forename: R
authors.initials: R
authors.lastname: Baumann
authors.forename: R
authors.initials: R
authors.lastname: Loup
authors.forename: L
authors.initials: L
authors.lastname: Girard
authors.forename: B
authors.initials: B
authors.lastname: Miazza
authors.forename: R
authors.initials: R
authors.lastname: de Peyer
authors.forename: E
authors.initials: E
authors.lastname: Loizeau
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002637:Chest Pain / Q000175:diagnosis* / Q000209:etiology; D004491:Edrophonium; D015154:Esophageal Motility Disorders / Q000150:complications / Q000175:diagnosis*; D005189:False Positive Reactions; D005260:Female; D005769:Gastrointestinal Motility / Q000187:drug effects; D006801:Humans; D008297:Male; D008365:Manometry / Q000379:methods; D008875:Middle Aged
chemical_list: D004491:Edrophonium
vernacular_title: Utilité discutable du test à l'édrophonium dans le diagnostic d'une douleur rétrosternale non cardiaque.