The role of venous and neural invasion on survival in rectal adenocarcinoma.
A total of 254 rectal adenocarcinomas were examined for the presence of venous and neural invasion. Both the incidence of venous and neural invasion increased with Astler-Coller's stage, except for stage C1 related to neural invasion. Both prognostic factors predicted significantly reduced actuarial survival rates in patients with node-negative tumors. Thus, examination for the presence of venous and neural invasion can add information to conventional staging in node-negative tumors for assessing prognosis after radical surgery for rectal adenocarcinoma.
Horn
A
A
Department of Surgery, Haukeland Hospital, University of Bergen.
Dahl
O
O
Morild
I
I
D000206:Actuarial Analysis; D000230:Adenocarcinoma / Q000098:blood supply / Q000401:mortality / Q000473:pathology*; D006801:Humans; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011379:Prognosis; D012004:Rectal Neoplasms / Q000098:blood supply / Q000401:mortality / Q000473:pathology*; D012007:Rectum / Q000098:blood supply / Q000294:innervation; D012307:Risk Factors