Locally advanced unresectable gastric cancer successfully resected after neoadjuvant chemotherapy with FADE regimen.
The prognosis of unresectable advanced gastric cancer is extremely poor. We tried a neoadjuvant chemotherapy in locally advanced unresectable stomach cancer diagnosed by initial explo-laparotomy. After chemotherapy with the FADE regimen (5-fluorouracil + adriamycin + cisplatin + etoposide), the patient was diagnosed clinically as a complete response state on re-staging with radiological gastrointestinal study, fiber-gastroscopy and computerized tomography. During the second-look operation, the advanced cancer was completely resected and the pathological diagnosis was early gastric cancer (EGC) type IIc, stage II (T1N2Mo).
Chung
H C
HC
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Roh
J K
JK
Park
Y J
YJ
Lee
S I
SI
Min
J S
JS
Lee
J T
JT
Lee
K B
KB
Kim
B S
BS
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000188:drug therapy*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage*; D003131:Combined Modality Therapy; D004317:Doxorubicin / Q000008:administration & dosage*; D005047:Etoposide / Q000008:administration & dosage*; D005472:Fluorouracil / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013270:Stomach / Q000000981:diagnostic imaging / Q000473:pathology; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery*; D014057:Tomography, X-Ray Computed
D005047:Etoposide; D004317:Doxorubicin; D002945:Cisplatin; D005472:Fluorouracil