Adenofibroma of the uterus: multiple recurrences following wide local excision.
The uterine adenofibroma is a form of mixed mesodermal tumor in which both epithelial and stromal components are benign. A case is presented in which a patient with this lesion was treated with excision of the tumor rather than hysterectomy. Two years later, she developed a recurrence of the lesion, which was again treated with wide local excision. A hysterectomy was done 9 months later, and a polypoid lesion was noted in the fundus of the uterus which on histologic examination was thought to be potentially either an adenofibroma precursor or a maturation of the previous cellular adenofibroma. Since uterine adenofibroma usually occurs in older patients, the standard treatment has been hysterectomy. Because of this patient's age, she was initially treated with a more conservative approach. However, despite the fact that the uterine adenofibroma is a benign lesion, it has an obvious potential to recur when treated conservatively.
Seltzer
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VL
Department of Obstetrics and Gynecology, Long Island Jewish Medical Center, New Hyde Park, New York.
Levine
A
A
Spiegel
G
G
Rosenfeld
D
D
Coffey
E L
EL
D000232:Adenofibroma / Q000473:pathology / Q000601:surgery*; D000328:Adult; D004715:Endometriosis / Q000473:pathology / Q000601:surgery; D005187:Fallopian Tubes / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D009364:Neoplasm Recurrence, Local; D009378:Neoplasms, Multiple Primary; D010052:Ovariectomy / Q000379:methods; D014594:Uterine Neoplasms / Q000473:pathology / Q000601:surgery*; D014599:Uterus / Q000473:pathology