Blue rubber-bleb naevus syndrome: report of a case with consumption coagulopathy complicated by manifest thrombosis.
Blue rubber-bleb naevus (BRBN) syndrome is a rare disorder characterized by subcutaneous and gastrointestinal haemangiomas. The latter may lead to bleeding complications. A case is reported in which a process of chronic intravascular coagulation resulted in serious thrombotic complications. In the presence of a chronic consumption coagulopathy, it remains uncertain whether antiplatelet drugs are of prophylactic antithrombotic value.
Hofhuis
W J
WJ
Department of Paediatrics, Erasmus University, Rotterdam, The Netherlands.
Oranje
A P
AP
Bouquet
J
J
Sinaasappel
M
M
D000743:Anemia, Hemolytic / Q000150:complications*; D001241:Aspirin / Q000627:therapeutic use; D004176:Dipyridamole / Q000627:therapeutic use; D004211:Disseminated Intravascular Coagulation / Q000150:complications*; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000150:complications*; D006392:Hemangioma, Cavernous / Q000150:complications*; D006801:Humans; D007223:Infant; D012878:Skin Neoplasms / Q000150:complications*; D013577:Syndrome; D013924:Thrombophlebitis / Q000188:drug therapy / Q000209:etiology*
D004176:Dipyridamole; D001241:Aspirin