[Studies on anti-tumor activity of crude drugs. II. The effects of aqueous extracts of some crude drugs in shortterm screening test. (2)].
The selective toxicity was often shown by experiments with in vitro screening test in human cancer cell (JTC-26) and human normal embryonic cell (HE-1) on the crude extract of crude drugs. The active fractions with selective toxicity were obtained by column chromatography. However, the selective toxicity disappeared in the simple constituent in which the activity remained. The selective toxicity of crude drugs was presumed to appear with the complex constituents.
Sato
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A
Institute of Osaka Oriental Medicine Co., Ltd., Japan.
D000972:Antineoplastic Agents, Phytogenic; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D006801:Humans; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal