title: [The anti-koro effect of a tricyclic antidepressant].
abstract: The authors are reporting a case of koro syndrome which was associated with major depression. Koro syndrome is a rare disease which manifests itself with a severe anxiety associated with the fear of having the penis shrinking and disappearing in the abdomen. The case reported was treated with trimipramine, a tricyclic antidepressant, at a dose of 150 mg/day associated with bromazepam, a benzodiazepine. In addition, the patient received psychotherapy, which allowed him to deal with the situation and to eliminate guilt feelings. It is hypothesized that the tricyclic antidepressant, by treating the depression, had a curative effect on the koro syndrome.
authors.affiliation: Centre de recherche, Unité psychopharmacologique, Hôpital Louis-H. Lafontaine, Montréal, Québec.
authors.forename: L
authors.initials: L
authors.lastname: Turnier
authors.forename: G
authors.initials: G
authors.lastname: Chouinard
mesh_terms: D000328:Adult; D001009:Anxiety, Castration / Q000188:drug therapy* / Q000523:psychology; D001960:Bromazepam / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003702:Delusions / Q000188:drug therapy*; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D003984:Dibenzazepines / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005239:Fear / Q000187:drug effects*; D006801:Humans; D008297:Male; D010200:Panic / Q000187:drug effects*; D011613:Psychotherapy; D014299:Trimipramine / Q000627:therapeutic use*
chemical_list: D003984:Dibenzazepines; D014299:Trimipramine; D001960:Bromazepam
vernacular_title: Effet anti-koro d'un antidépresseur tricyclique.