[Evaluation of the effectiveness of regional interleukin-2 dependent adoptive immunocytotherapy of mice with transplanted rhabdomyosarcoma].
Alternative principles of regional IL-2-dependent adoptive immunocytotherapy of malignant tumours are suggested. Regional adoptive immunocytotherapy consists in the administration of the short-term IL-2 treated lymphocytes of the lymph nodes removed from the tumour which have tumour-associated suppressor activity and spleen cells after elimination of cells with the immunosuppressive activity.
Semenova-Kobzar'
R A
RA
Iudin
V M
VM
Kushko
L Ia
LIa
Iakhimovich
L V
LV
Berezhnaia
N M
NM
D000818:Animals; D010478:Chemotherapy, Cancer, Regional Perfusion; D007116:Immunization, Passive; D007376:Interleukin-2 / Q000008:administration & dosage*; D008198:Lymph Nodes / Q000166:cytology; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009368:Neoplasm Transplantation; D012208:Rhabdomyosarcoma / Q000628:therapy*; D012513:Sarcoma, Experimental / Q000628:therapy*; D013154:Spleen / Q000166:cytology
D007376:Interleukin-2
Otsenka éffektivnosti regionarnoĭ interleĭkin-2-zavisimoĭ adoptivnoĭ immunotsitoterapii mysheĭ s perevivnoĭ rabdomiosarkomoĭ.