title: A new technique for delivering antegrade/retrograde blood cardioplegia without right heart isolation.
abstract: We report our updated experience with combined antegrade/retrograde cardioplegia using a self-inflating/deflating balloon cannula that allows rapid transatrial retrograde coronary sinus cannulation (10-15 s) without right heart isolation. This permits routine single venous cannulation and optimizes myocardial protection when combined with antegrade cardioplegia. Two hundred fifty-five consecutive patients underwent antegrade/retrograde cardioplegia. Initial antegrade blood cardioplegia caused immediate arrest (less than 1 min), and the cardioplegic dose was divided equally between antegrade and retrograde delivery. Included are 173 isolated CABG patients (39 with either extending infarction, cardiogenic shock, or ejection fraction less than 20%), and 37 coronary reoperations, 67 with aortic and/or mitral valve procedures, 3 with arrhythmia surgery, and 7 children (VSD, Rastelli, Konno, etc). Septal temperature in patients with LAD occlusion fell to 11.6 degrees C +/- 0.5 after retrograde vs only 16.1 degrees C +/- 3 after antegrade cardioplegia (p less than 0.05). Overall hospital mortality was 2.8% and no complications followed transatrial retrograde coronary sinus cannulation. Antegrade/retrograde cardioplegia allowed retrograde flushing of debris in redo coronary operations, produced immediate arrest with low cardioplegic volumes, improved cardioplegic distribution during IMA grafting, allowed aortic and mitral valve procedures to proceed uninterrupted, and ensured distribution in unforeseen aortic insufficiency. Antegrade/retrograde cardioplegia is now used routinely in all adult and in many pediatric operations because of its speed, safety, and simplicity.
authors.affiliation: Department of Surgery, UCLA School of Medicine.
authors.forename: G D
authors.initials: GD
authors.lastname: Buckberg
authors.forename: D C
authors.initials: DC
authors.lastname: Drinkwater
authors.forename: H
authors.initials: H
authors.lastname: Laks
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002314:Cardioplegic Solutions / Q000008:administration & dosage*; D002404:Catheterization / Q000379:methods; D002648:Child; D002675:Child, Preschool; D001026:Coronary Artery Bypass / Q000379:methods; D005260:Female; D006324:Heart Arrest, Induced / Q000379:methods*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D015425:Myocardial Reperfusion / Q000379:methods*
chemical_list: D002314:Cardioplegic Solutions