Ciliated cells in the human gastric mucosa. Evidence of metaplastic change.
In the gastric mucosa of Japanese patients, ciliated cells were found in association with intestinal metaplasia. The cells occurred frequently in the pyloric mucosa of nearly half of the cases examined but rarely in the cardiac mucosa of total 12 cases, but never adjacent to the chief cells of gastric glands. The ciliated cells were always found in the basal part of cardiac and pyloric glands, but never in the surface or in the foveolar epithelium. Furthermore, ciliated cells containing a few small mucus granules and simultaneously possessing numerous cilia and basal bodies were noted. Ciliated cells in the gastric mucosa have been found mainly in elderly Japanese patients, but were also observed exceptionally in one Chinese, two Swedes and one American. These ciliated cells are not present in the normal human gastric and intestinal mucosa, and therefore a new term, "ciliated metaplasia", is proposed for their occurrence.
Torikata
C
C
Department of Pathology, Keio University School of Medicine, Tokyo, Japan.
Mukai
M
M
Kawakita
H
H
D002923:Cilia / Q000648:ultrastructure; D005260:Female; D005753:Gastric Mucosa / Q000166:cytology / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007413:Intestinal Mucosa / Q000166:cytology; D008297:Male; D008679:Metaplasia / Q000473:pathology; D008854:Microscopy, Electron; D010437:Peptic Ulcer / Q000473:pathology; D013274:Stomach Neoplasms / Q000473:pathology