title: [Interaction of xenobiotics and the body from the viewpoint of biokinetics].
abstract: On the basis of biokinetic principles with account of the concept of receptors in toxicology there were derived equations of concentration/time/effect relationship to describe both nonreversible and reversible interaction of xenobiotics and receptors in a critical organ regarded as a unique compartment responsible for xenobiotic toxic effect. An example of calculating xenoreceptor concentration in a critical organ was given.
authors.forename: V N
authors.initials: VN
authors.lastname: Pavlov
mesh_terms: D006801:Humans; D007700:Kinetics; D007928:Lethal Dose 50; D008954:Models, Biological; D015262:Xenobiotics
chemical_list: D015262:Xenobiotics
vernacular_title: Vzaĭmodeĭstvie ksenobiotikov i organizma s pozitsiĭ biokinetiki.