[The storiform M-8333/1,3 neurofibroma].
Attention concentrated on features of storiform neurofibroma failed to find an unambiguous universal interpretation. 15 consecutively published cases were collectively revised with partial conclusions from a comparison of findings and references: Nosological identity of dermatofibrosarcoma protuberans and its "pigmented variant" is substantiated but fails to solve histogenetic embarrassment of both items. Characteristic storiform structure is connected with layered very flat cells. No doubt they remind of spindle-shaped fibroblasts in cross section but flat dendritic cells remain an essential component no matter whether pigmented or not. Open to discuss is whether fibroblasts belong to adaptable cells which generally can get a flat shape among dendritic cells. Their pigmentation may have local origin according to paraneuronal theory.
Bednár
B
B
Hlavův I. patologickoanatomický ústav FVL UK, Praha.
D005354:Fibrosarcoma / Q000473:pathology*; D006801:Humans; D012878:Skin Neoplasms / Q000473:pathology*
Storiformní neurofibrom M-8833/1, 3.