Growth cone morphology, axon trajectory and branching patterns in the neonatal rat corpus callosum.
The pattern of outgrowth of visual callosal axons was studied in neonatal rats. Both the pioneer axons and the main fascicle grow laterally and ventrally past their topographically appropriate target. Side branches of these axons penetrate the overlying gray matter in the target area. Growth cones with the most complex morphologies were seen in the midline area.
Hogan
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Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City 66103.
Berman
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NE
D000818:Animals; D000831:Animals, Newborn; D001369:Axons / Q000502:physiology* / Q000648:ultrastructure; D002454:Cell Differentiation; D003337:Corpus Callosum / Q000166:cytology* / Q000502:physiology; D009473:Neuronal Plasticity; D051381:Rats