title: Premalignant changes in nasal and sinus polyps: a retrospective 10 year study (1979-1988).
abstract: One hundred and seventy cases of nasal and/or sinus polyps diagnosed in the Pathology Service of the Hospital Militar Central GOMEZ/ULLA of Madrid (Spain) between 1.9.79 and 1.9.88 are reviewed. In two cases areas of 'carcinoma in situ' in the epithelium covering the polyps were demonstrated. The literature is reviewed for reports of malignant transformation and dysplastic changes in nasal and sinusal polyps. We suggest that precancerous changes may occasionally be noted in inflammatory lesions, a fact that pathologists should keep in mind.
authors.affiliation: Hospital Militar Central Gomez-Ulla, Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: de la Cruz Mera
authors.forename: M J
authors.initials: MJ
authors.lastname: Sánchez López
authors.forename: E
authors.initials: E
authors.lastname: Merino Royo
authors.forename: L
authors.initials: L
authors.lastname: Requena
mesh_terms: D000368:Aged; D002278:Carcinoma in Situ / Q000473:pathology*; D006801:Humans; D008297:Male; D009298:Nasal Polyps / Q000473:pathology*; D010255:Paranasal Sinus Neoplasms / Q000473:pathology*; D010256:Paranasal Sinuses / Q000473:pathology; D011127:Polyps / Q000473:pathology*; D012189:Retrospective Studies