Genetic loci ordering instability: an example.
In attempting to establish the order of genetic loci by constructing a map from pairwise linkage data, one assumes that the loci satisfy a linear-order relation. If the data utilized in the construction are not consistent with the linear-order assumption, then a very small change in the data may lead to a large qualitative change in the map. An example of such an instability is presented in this paper.
Falk
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Department of Physics, City College of the City University of New York.
Falk
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D002874:Chromosome Mapping; D005796:Genes; D008040:Genetic Linkage; D008433:Mathematics; D008957:Models, Genetic