[The characteristics of the changes in the aortic endothelium of old rabbits administered adrenaline].
The effect of sharp increase of arterial pressure and blood adrenalin content on the vascular endothelium increases with age. Structural disorders and disturbances in permeability of aortic endothelium after 30-minute adrenalin infusion are more marked in old rabbits. This may be among the factors which induce intensified development of preatherosclerotic changes in the vessels.
Kozhura
I P
IP
Kopylova
G V
GV
D000375:Aging / Q000187:drug effects*; D000818:Animals; D001011:Aorta / Q000187:drug effects* / Q000648:ultrastructure; D001794:Blood Pressure / Q000187:drug effects; D002199:Capillary Permeability / Q000187:drug effects; D004730:Endothelium, Vascular / Q000187:drug effects* / Q000648:ultrastructure; D004837:Epinephrine / Q000097:blood / Q000494:pharmacology*; D008297:Male; D008854:Microscopy, Electron; D008856:Microscopy, Fluorescence; D011817:Rabbits; D013997:Time Factors; D014343:Trypan Blue
D014343:Trypan Blue; D004837:Epinephrine
Osobennosti izmenenia éndoteliia aorty starykh krolikov pri vvedenii adrenalina.