title: A facile synthesis of 1,5-diphenyl-3-(substituted oxy)-1H-1,2,4-triazoles.
abstract: A series of 1,5-diphenyl-3-alkoxy (or acyloxy)-1H-1,2,4-triazoles were synthesized and assayed in the rat adjuvant induced arthritis model. Some compounds show significant anti-inflammatory activity.
authors.affiliation: Institute for Drug Research, Budapest, Hungary.
authors.forename: L
authors.initials: L
authors.lastname: Czollner
authors.forename: G
authors.initials: G
authors.lastname: Szilágyi
authors.forename: J
authors.initials: J
authors.lastname: Langó
authors.forename: J
authors.initials: J
authors.lastname: Janáky
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis*; D001169:Arthritis, Experimental / Q000188:drug therapy; D001555:Benzene Derivatives / Q000138:chemical synthesis* / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D008297:Male; D051381:Rats; D014230:Triazoles / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D001555:Benzene Derivatives; D014230:Triazoles