Poly(A) metabolism and polysomal recruitment of maternal mRNAs during early Xenopus development.
Up to the midblastula stage, cell division in Xenopus is directed by maternal mRNAs and proteins that are inherited by the fertilized egg. We have isolated cDNA clones for mRNAs that undergo either adenylation or deadenylation during this developmental period. Coincidental with this poly(A) metabolism are changes in polysomal localization. The relationship between polyadenylation and translation is discussed.
Paris
J
J
Laboratoire de biologie et genetique du developpement, CNRS URA 256, Universite de Rennes I, France.
Philippe
M
M
D000818:Animals; D015152:Blotting, Northern; D005260:Female; D015723:Gene Library; D009865:Oocytes / Q000378:metabolism; D011061:Poly A / Q000378:metabolism*; D011132:Polyribosomes / Q000378:metabolism*; D011247:Pregnancy; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000378:metabolism*; D014981:Xenopus / Q000196:embryology*
D012333:RNA, Messenger; D011061:Poly A