title: Mechanical properties of human forearm and vulvar skin.
abstract: Using a newly developed suction device, the mechanical properties of forearm and vulvar skin were studied in 22 healthy women, 12 before and 10 after the menopause. The ratio between viscous deformation (Uv) and elastic deformation (Ue) and the biological elasticity, i.e. the ratio between immediate recovery (Ur) and total deformation (Uf), were both significantly lower in vulvar than in forearm skin. Ur/Uf decreased significantly with load in vulvar, but not in forearm skin, whereas Uv/Ue was not load-dependent in either site. Uv/Ue remained constant with age in both test sites, whereas Ur/Uf was significantly lower in post-menopausal women in both forearm and vulvar skin. In vulvar, but not in forearm skin, Uv/Ue was significantly correlated with body height which may be an indicator of mechanical connective tissue properties. Viscous deformation plays a lesser role and biological elasticity is decreased in vulvar compared to forearm skin. Despite differences in mechanical parameters at both sites, age-related changes seem to be similar.
authors.affiliation: Department of Dermatology, School of Medicine, University of California, San Francisco 94143-0989.
authors.forename: P
authors.initials: P
authors.lastname: Elsner
authors.forename: D
authors.initials: D
authors.lastname: Wilhelm
authors.forename: H I
authors.initials: HI
authors.lastname: Maibach
mesh_terms: D000328:Adult; D000368:Aged; D001696:Biomechanical Phenomena; D001827:Body Height; D004548:Elasticity; D005260:Female; D005542:Forearm; D006801:Humans; D008593:Menopause / Q000502:physiology; D008875:Middle Aged; D012879:Skin Physiological Phenomena; D013314:Stress, Mechanical; D013396:Suction; D014844:Vulva / Q000502:physiology*