title: Adenofibroma of the uterus: multiple recurrences following wide local excision.
abstract: The uterine adenofibroma is a form of mixed mesodermal tumor in which both epithelial and stromal components are benign. A case is presented in which a patient with this lesion was treated with excision of the tumor rather than hysterectomy. Two years later, she developed a recurrence of the lesion, which was again treated with wide local excision. A hysterectomy was done 9 months later, and a polypoid lesion was noted in the fundus of the uterus which on histologic examination was thought to be potentially either an adenofibroma precursor or a maturation of the previous cellular adenofibroma. Since uterine adenofibroma usually occurs in older patients, the standard treatment has been hysterectomy. Because of this patient's age, she was initially treated with a more conservative approach. However, despite the fact that the uterine adenofibroma is a benign lesion, it has an obvious potential to recur when treated conservatively.
authors.affiliation: Department of Obstetrics and Gynecology, Long Island Jewish Medical Center, New Hyde Park, New York.
authors.forename: V L
authors.initials: VL
authors.lastname: Seltzer
authors.forename: A
authors.initials: A
authors.lastname: Levine
authors.forename: G
authors.initials: G
authors.lastname: Spiegel
authors.forename: D
authors.initials: D
authors.lastname: Rosenfeld
authors.forename: E L
authors.initials: EL
authors.lastname: Coffey
mesh_terms: D000232:Adenofibroma / Q000473:pathology / Q000601:surgery*; D000328:Adult; D004715:Endometriosis / Q000473:pathology / Q000601:surgery; D005187:Fallopian Tubes / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D009364:Neoplasm Recurrence, Local; D009378:Neoplasms, Multiple Primary; D010052:Ovariectomy / Q000379:methods; D014594:Uterine Neoplasms / Q000473:pathology / Q000601:surgery*; D014599:Uterus / Q000473:pathology