title: Synthesis of the tetrasaccharide repeating-unit of the polysaccharide from Klebsiella type 23.
abstract: Methyl 2-O-allyl-4-O-benzyl-3-O-(2,3,4,6-tetra-O-acetyl-beta-D- glucopyranosyl)-alpha-L-rhamnospyranoside was obtained by condensing methyl 2-O-allyl-4-O-benzyl-alpha-L-rhamnopyranoside with tetra-O-acetyl-alpha-D-glucopyranosyl bromide. Benzylation, removal of the allyl group, and condensation of the product with ethyl 6-O-acetyl-2,3,4-tri-O-benzyl-1-thio-beta-D-glucopyranoside gave methyl 2-O-(6-O-acetyl-2,3,4-tri-O-benzyl-alpha-D-glucopyranosyl)-4-O-benzyl-3- O- (2,3,4,6-tetra-O-benzyl-beta-D-glucopyranosyl)-alpha-L-rhamnopyranoside. O-Deacetylation, condensation of the product with methyl (2,3,4-tri-O-acetyl-alpha-D-glucopyranosyl bromide)-uronate, and removal of the protecting groups gave methyl 3-O-beta-D-glucopyranosyl-2-O-[6-O-(beta-D-glucopyranosyluronic acid)-alpha-D-glucopyranosyl]-alpha-L-rhamnopyranoside (13).
authors.affiliation: Department of Biological Chemistry, Indian Association for the Cultivation of Science, Calcutta.
authors.forename: A K
authors.initials: AK
authors.lastname: Ray
authors.forename: N
authors.initials: N
authors.lastname: Roy
mesh_terms: D002240:Carbohydrate Sequence; D007709:Klebsiella; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D009844:Oligosaccharides / Q000138:chemical synthesis*; D011135:Polysaccharides, Bacterial / Q000138:chemical synthesis*
chemical_list: D009844:Oligosaccharides; D011135:Polysaccharides, Bacterial; C064323:methyl 3-O-glucopyranosyl-2-O-(6-O-(glucopyranosyluronic acid)glucopyranosyl)rhamnopyranoside