[The effect of mitochondrial Ca 2+-transporting Ca 2+-binding glycoprotein on development of Ehrlich ascites carcinoma].
Single administration of Ca2(+)-transporting-Ca2(+)-binding glycoprotein simultaneously with intraperitoneal inoculation of Ehrlich ascites tumor cells into mice led to a decrease in the animals weight growth by approximately 34% as compared with the animals which were not treated with the glycoprotein. The effect observed was clearly pronounced, especially within the first days after inoculation of Ehrlich ascites tumor. Lifetime of individual experimental animals was increased whereas that of the whole group remained unchanged.
Sirota
T V
TV
Utesheva
Zh A
ZhA
D000818:Animals; D002135:Calcium-Binding Proteins / Q000302:isolation & purification / Q000494:pharmacology*; D002286:Carcinoma, Ehrlich Tumor / Q000473:pathology / Q000503:physiopathology / Q000517:prevention & control*; D006023:Glycoproteins / Q000302:isolation & purification / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008929:Mitochondria, Heart / Q000032:analysis; D015430:Weight Gain / Q000187:drug effects
D002135:Calcium-Binding Proteins; D006023:Glycoproteins
Vliianie mitokhondrial'nogo Ca 2+-transportiruiushchego Ca 2+-sviazyvaiushchego glikoproteina na razvitie astsitnoĭ kartsinomy Erlikha.