title: Reduced regional cerebral metabolic rate for glucose at the terminal stage in a case of late infantile neuronal ceroid lipofuscinosis.
abstract: Regional cerebral metabolic rate for glucose was determined for six different areas of the gray matter in an 8-year-old girl with late infantile neuronal ceroid lipofuscinosis. In all regions, the rates were almost half of the control values. The regional cerebral metabolic rate for glucose was relatively preserved in the striatal region and severely reduced in the frontal cortex.
authors.affiliation: Department of Pediatrics, Tohoku University School of Medicine, Sendai, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Fueki
authors.forename: K
authors.initials: K
authors.lastname: Iinuma
authors.forename: A
authors.initials: A
authors.lastname: Kojima
authors.forename: K
authors.initials: K
authors.lastname: Yanai
authors.forename: K
authors.initials: K
authors.lastname: Haginoya
authors.forename: K
authors.initials: K
authors.lastname: Tada
authors.forename: T
authors.initials: T
authors.lastname: Ido
authors.forename: M
authors.initials: M
authors.lastname: Ito
mesh_terms: D001786:Blood Glucose / Q000378:metabolism*; D001921:Brain / Q000000981:diagnostic imaging*; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000000981:diagnostic imaging; D002648:Child; D003241:Consanguinity; D003342:Corpus Striatum / Q000000981:diagnostic imaging; D003847:Deoxyglucose / Q000031:analogs & derivatives / Q000378:metabolism; D004734:Energy Metabolism / Q000502:physiology; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D009472:Neuronal Ceroid-Lipofuscinoses / Q000000981:diagnostic imaging* / Q000235:genetics; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed
chemical_list: D001786:Blood Glucose; D019788:Fluorodeoxyglucose F18; D003847:Deoxyglucose