title: Two-dimensional electrophoresis of heart muscle proteins in human cardiomyopathies.
abstract: Human heart muscle proteins have been analyzed by two-dimensional electrophoresis. Twenty five autopsy heart muscle samples obtained from individuals who had died in accidents and who had no signs of cardiovascular pathology have been compared with biopsy and autopsy myocardium samples of patients with: dilated cardiomyopathy (5 cases), hypertrophical cardiomyopathy (2 cases) and myocarditis (2 cases). In dilated cardiomyopathy in 3 out of 5 cases an additional protein spot was found in the myocardial myosin light chain 1 area.
authors.affiliation: Institute of Medical Genetics, Academy of Medical Sciences of the USSR, Moscow.
authors.forename: L I
authors.initials: LI
authors.lastname: Kovalyov
authors.forename: V G
authors.initials: VG
authors.lastname: Naumov
authors.forename: H V
authors.initials: HV
authors.lastname: Pulyayeva
authors.forename: A M
authors.initials: AM
authors.lastname: Samko
authors.forename: M N
authors.initials: MN
authors.lastname: Tsvetkova
authors.forename: S S
authors.initials: SS
authors.lastname: Shishkin
authors.forename: N M
authors.initials: NM
authors.lastname: Mukharlyamov
mesh_terms: D009202:Cardiomyopathies / Q000378:metabolism*; D002311:Cardiomyopathy, Dilated / Q000378:metabolism; D002312:Cardiomyopathy, Hypertrophic / Q000378:metabolism; D015180:Electrophoresis, Gel, Two-Dimensional; D006321:Heart / Q000196:embryology; D006801:Humans; D009124:Muscle Proteins / Q000378:metabolism*; D009205:Myocarditis / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism*; D009218:Myosins / Q000378:metabolism
chemical_list: D009124:Muscle Proteins; D009218:Myosins