CSF beta-endorphins in childhood neuropsychiatric disorders.
Thirty-one children with autistic disorder, 8 with the Rett syndrome (RS), 2 with childhood disintegrative disorder and 5 with infantile spasms were compared with healthy adult controls with respect to cerebrospinal fluid (CSF) beta-endorphin levels. The autistic disorder and RS groups showed significantly lower values than the other groups. There were no age trends within the various groups. Further study of CSF beta-endorphins in these disorders and blindly examined age matched controls is warranted.
Gillberg
C
C
Child Neuropsychiatry Centre, University of Gothenburg, Sweden.
Terenius
L
L
Hagberg
B
B
Witt-Engerström
I
I
Eriksson
I
I
D000293:Adolescent; D001321:Autistic Disorder / Q000134:cerebrospinal fluid*; D001927:Brain Diseases / Q000134:cerebrospinal fluid* / Q000523:psychology; D002648:Child; D002675:Child, Preschool; D004723:Endorphins / Q000134:cerebrospinal fluid*; D005260:Female; D006801:Humans; D008297:Male; D015518:Rett Syndrome / Q000134:cerebrospinal fluid*
D004723:Endorphins