title: Anaesthesia for the treatment of a giant cerebral aneurysm under hypothermic circulatory arrest.
abstract: The anaesthetic management of a patient whose giant cerebral aneurysm was clipped is described. Profound hypothermia and thiopentone were used to provide cerebral protection during circulatory arrest. Atracurium was used to provide muscle relaxation; the level of neuromuscular block and plasma concentrations of atracurium and laudanosine were measured.
authors.affiliation: Department of Anaesthesia, Manchester Royal Infirmary.
authors.forename: A N
authors.initials: AN
authors.lastname: Thomas
authors.forename: J M
authors.initials: JM
authors.lastname: Anderton
authors.forename: N J
authors.initials: NJ
authors.lastname: Harper
mesh_terms: D000328:Adult; D000768:Anesthesia, General; D001279:Atracurium / Q000008:administration & dosage / Q000097:blood; D005260:Female; D005283:Fentanyl; D006324:Heart Arrest, Induced; D006801:Humans; D007036:Hypothermia, Induced; D002532:Intracranial Aneurysm / Q000097:blood / Q000601:surgery*; D007530:Isoflurane; D007546:Isoquinolines / Q000097:blood; D013874:Thiopental
chemical_list: D007546:Isoquinolines; D001279:Atracurium; D007530:Isoflurane; C001522:laudanosine; D013874:Thiopental; D005283:Fentanyl