title: [Evaluation of the clinical significance of determining the level of plasma fibronectin in acute poisoning].
abstract: Changes in plasma fibronectin (FN) levels in acute toxic conditions have been studied in 24 patients. A significant reduction of FN concentration was found within the first days of the disease; further changes in the FN levels are related to the disease outcome and have a prognostic value. An inverse correlation was found between the FN concentration and other blood biochemical parameters (LDH, creatinine, and urea). Developed renal insufficiency in the presence of hypofibronectinemia suggests a poor prognosis of the disease.
authors.forename: I I
authors.initials: II
authors.lastname: Shimanko
authors.forename: A A
authors.initials: AA
authors.lastname: Nazarenko
authors.forename: S K
authors.initials: SK
authors.lastname: Osmanov
authors.forename: G I
authors.initials: GI
authors.lastname: Tsepliaeva
authors.forename: N S
authors.initials: NS
authors.lastname: Kuz'mina
authors.forename: Iu N
authors.initials: IuN
authors.lastname: Lebedeva
authors.forename: L N
authors.initials: LN
authors.lastname: Zimina
mesh_terms: D000208:Acute Disease; D005353:Fibronectins / Q000097:blood*; D006801:Humans; D011041:Poisoning / Q000097:blood*; D011379:Prognosis
chemical_list: D005353:Fibronectins
vernacular_title: Otsenka klinicheskoĭ znachimosti opredeleniia urovnia plazmennogo fibronektina pri ostrykh toksicheskikh porazheniiakh.