title: Ventilation parameters and arterial blood gases as a prediction of hypoplasia in congenital diaphragmatic hernia.
abstract: Attempts to predict the degree of pulmonary hypoplasia associated with congenital diaphragmatic hernia have been made by evaluating the ventilation parameters and the arterial blood gasses of these patients. A CO2 index as a predictor of outcome, which correlates the PaCO2 with the ventilation index, was recently proposed. However, in this study the postductal PaO2 was a better predictor of survival. And the so-called "honeymoon period" was a better indicator of the efficacy of extracorporeal membrane oxygenation (ECMO) than the CO2 index. Nineteen patients were evaluated; 11 were treated with ECMO, and eight were not considered suitable for ECMO.
authors.affiliation: Department of Neonatology, Huntington Memorial Hospital, Pasadena, CA.
authors.forename: P W
authors.initials: PW
authors.lastname: Johnston
authors.forename: R
authors.initials: R
authors.lastname: Liberman
authors.forename: E
authors.initials: E
authors.lastname: Gangitano
authors.forename: J
authors.initials: J
authors.lastname: Vogt
mesh_terms: D000403:Airway Resistance; D001784:Blood Gas Analysis; D015199:Extracorporeal Membrane Oxygenation; D006548:Hernia, Diaphragmatic / Q000097:blood / Q000503:physiopathology; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000002:abnormalities* / Q000503:physiopathology; D011184:Postoperative Period; D012123:Pulmonary Ventilation; D015656:Respiratory Mechanics