title: Treatment of idiopathic spasmodic torticollis with botulinum-A toxin: a pilot study of 19 patients.
abstract: Nineteen patients with spasmodic torticollis, unresponsive to standard therapy, were administered local injections of botulinum-A toxin into the affected muscles. During an average follow-up period of 11.5 months, a more than 25% improvement was noted in 14 of 19 patients. All those with purely focal dystonia and 9 of 10 patients with a disease history of less than three years benefited from treatment. Side effects were insignificant and transient. Botulinum toxin is a very effective and safe method of treatment for spasmodic torticollis.
authors.affiliation: Westmead Hospital, NSW.
authors.forename: I T
authors.initials: IT
authors.lastname: Lorentz
authors.forename: S S
authors.initials: SS
authors.lastname: Subramaniam
authors.forename: C
authors.initials: C
authors.lastname: Yiannikas
mesh_terms: D000328:Adult; D000368:Aged; D001905:Botulinum Toxins / Q000627:therapeutic use*; D004421:Dystonia / Q000188:drug therapy / Q000503:physiopathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009128:Muscle Spasticity / Q000188:drug therapy / Q000503:physiopathology; D010865:Pilot Projects; D011379:Prognosis; D014103:Torticollis / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D001905:Botulinum Toxins