[Therapy of malignant pheochromocytoma using I-131 metaiodobenzylguanidine--report of a case].
A 67 year-old-female had multiple metastases to her lung, liver and paraaortic lymph nodes from a post-operative malignant pheochromocytoma. She was treated with 3.7 GBq (100 mCi) of I-131 metaiodobenzylguanidine (MIBG). Metastatic nodules in lung and liver almost disappeared and the secretion of catecholamines decreased than baseline rates. However, major but temporary untoward response, such as hypertension and hyperglycemia, was seen after the I-131 MIBG administration.
Okazawa
H
H
Department of Radiology and Nuclear Medicine, Kyoto University Hospital.
Endo
K
K
Saga
T
T
Watanabe
Y
Y
Nakai
T
T
Kasagi
K
K
Konishi
J
J
Abe
M
M
Goto
K
K
Nakao
K
K
D019797:3-Iodobenzylguanidine; D000310:Adrenal Gland Neoplasms / Q000532:radiotherapy*; D000368:Aged; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D007462:Iodobenzenes / Q000627:therapeutic use*; D008113:Liver Neoplasms / Q000532:radiotherapy / Q000556:secondary*; D008175:Lung Neoplasms / Q000532:radiotherapy / Q000556:secondary*; D010673:Pheochromocytoma / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery
D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D019797:3-Iodobenzylguanidine