Antiplatelet components in Panax ginseng.
Panaxynol and ginsenosides Ro, Rg1, and Rg2 were found to be the main antiplatelet components in the diethyl ether and 1-butanol fractions, respectively, during the activity-guided fractionation of Panax ginseng, Panaxynol inhibited the aggregation, release reaction, and thromboxane formation in rabbit platelets while ginsenosides Ro, Rg1, and Rg2 suppressed the release reaction only.
Kuo
S C
SC
Graduate Institute of Pharmaceutical Chemistry, China Medical College, Taichung, Taiwan.
Teng
C M
CM
Lee
J C
JC
Ko
F N
FN
Chen
S C
SC
Wu
T S
TS
D000818:Animals; D005894:Panax / Q000032:analysis*; D010946:Plants, Medicinal; D010975:Platelet Aggregation Inhibitors / Q000032:analysis*; D011817:Rabbits
D010975:Platelet Aggregation Inhibitors