title: C-reactive protein concentrations pre- and post-transfusion.
abstract: In a prospective study, serum C-reactive protein (CRP) levels were analysed before and after 18 transfusional episodes, using a fluorescence polarization immunoassay. Only patients with a stable CRP value for two consecutive days before transfusion were assessed. Although small rises in CRP concentrations occurred following 55.6% of transfusions, there was no statistically significant difference between pre- and post-transfusion CRP values, and these increases also failed to reach clinical significance. An increase in CRP post-transfusion of greater than 100 mg/l occurred on only one occasion, and was more likely to be due to underlying infection.
authors.affiliation: Department of Haematology, St Vincent's Hospital, Dublin, Ireland.
authors.forename: H
authors.initials: H
authors.lastname: Enright
authors.forename: M
authors.initials: M
authors.lastname: Coyle
authors.forename: L G
authors.initials: LG
authors.lastname: O'Connell
mesh_terms: D001803:Blood Transfusion; D002097:C-Reactive Protein / Q000378:metabolism*; D015200:Fluoroimmunoassay; D006801:Humans; D007239:Infections / Q000097:blood; D011446:Prospective Studies; D013997:Time Factors
chemical_list: D002097:C-Reactive Protein