[Cytoskeletal principles of the functional organization of cells].
The paper provides basic information on cytoskeletal structures [microtubules, microfilaments and intermediate filaments] which form a very dynamic system in the cytoplasm and in specialized cellular structures. The cytoskeleton comprises also the membrane and nuclear skeleton. The cytoskeleton performs all motor functions of the cell, incl. intracellular transport, some morphogenic processes and it is the carrier of positional information in the cell and probably also the memory structure of non-genetic cell memory. The author mentions some molecular mechanisms of transformation of the chemical energy into mechanical energy. The article indicates also some perspectives of the application of findings in the sphere of medicine, in particular in the biology of tumour cells, in the pathogenesis of some diseases, in cytostatic treatment, in toxicology and in diagnostic applications.
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Katedra biologie lékarské fakulty Univerzity J. E. Purkynĕ Brno.
D003599:Cytoskeleton / Q000502:physiology*
Cytoskeletální princip funkcní organizace bunky.