Exposure of health care workers to ribavirin during therapy for respiratory syncytial virus infections.
Health care workers (HCW) are exposed to ribavirin aerosol during therapy of infants with respiratory syncytial virus infections. To assess the degree of HCW exposure, we analyzed air samples from patient rooms and HCW personal breathing zones during ribavirin aerosol delivery by ventilator (two samples), oxygen hood (two samples), and a new vacuum exhaust hood (four samples). HCW exposure to ribavirin during aerosol delivery by ventilator or vacuum exhaust hood system was substantially lower than HCW exposure during aerosol delivery by oxygen hood in rooms with adequate ventilation.
Bradley
J S
JS
Department of Pediatrics, University of California, San Diego, La Jolla 92093.
Connor
J D
JD
Compogiannis
L S
LS
Eiger
L L
LL
D000336:Aerosols; D000395:Air Pollutants, Occupational / Q000032:analysis; D004781:Environmental Exposure; D006801:Humans; D010348:Patient Care Team; D012134:Respiratory Protective Devices; D012136:Respiratory Syncytial Viruses; D010253:Respirovirus Infections / Q000188:drug therapy*; D012254:Ribavirin / Q000032:analysis / Q000097:blood / Q000627:therapeutic use*; D012263:Ribonucleosides / Q000627:therapeutic use*
D000336:Aerosols; D000395:Air Pollutants, Occupational; D012263:Ribonucleosides; D012254:Ribavirin