title: The value of umbilical blood 2,3 diphosphoglycerate levels in the diagnosis of chronic fetal hypoxia.
abstract: The authors assessed the levels of lactate and 2,3 diphosphoglycerate in the umbilical blood of 105 full-term neonates. A significant increase was found in the levels of 2,3 diphosphoglycerate in newborns of mothers with a history of imminent chronic intrauterine hypoxia. The lactate levels of these newborns were the same as in children of mothers without a history showing a risk of intrauterine hypoxia. The psychomotor development of newborns with increased levels of 2,3 diphosphoglycerate was significantly more altered than in those with normal levels in their first year of life.
authors.affiliation: Institute for Care of Mother and Child, Prague.
authors.forename: M
authors.initials: M
authors.lastname: Zapadlo
authors.forename: J
authors.initials: J
authors.lastname: Böswart
authors.forename: J
authors.initials: J
authors.lastname: Petová
authors.forename: K
authors.initials: K
authors.lastname: Hosková
mesh_terms: D019794:2,3-Diphosphoglycerate; D002908:Chronic Disease; D004163:Diphosphoglyceric Acids / Q000097:blood*; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D005312:Fetal Blood / Q000032:analysis*; D005311:Fetal Hypoxia / Q000175:diagnosis*; D006801:Humans; D007231:Infant, Newborn; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D011247:Pregnancy; D011248:Pregnancy Complications
chemical_list: D004163:Diphosphoglyceric Acids; D007773:Lactates; D019794:2,3-Diphosphoglycerate; D019344:Lactic Acid