title: Steady state kinetics of enzymes with substrates having multiple reaction sites.
abstract: An enzyme catalysing the reaction of a substrate with multiple reaction sites may display steady state kinetics described by a Michaels-Menten equation. The Km is identical for all sites considered individually and all sites together. The maximum velocity for a single site depends on the rate constants for reaction at that site and at all of other sites.
authors.affiliation: Department of Biochemistry, Memorial University, St. John's, Newfoundland, Canada.
authors.forename: E A
authors.initials: EA
authors.lastname: Barnsley
mesh_terms: D000818:Animals; D002384:Catalysis; D004798:Enzymes / Q000378:metabolism*; D007700:Kinetics; D008954:Models, Biological
chemical_list: D004798:Enzymes