[Growth of the axons in organotypic culture of the spinal cord].
Peculiarities of the axons growth in the culture of 14-day old chick embryo spinal cord after 24, 48 hr, 3, 5 and 7 days in the Maximov's chamber were observed. For the stimulation of axon growth the spinal cord was cultivated simultaneously with the explants of the muscle tissue and in the medium after the addition of supernatant of the somatic muscle. It has been demonstrated that the growth of the axons stimulated with the muscle explants or muscle supernatant takes place through the growth cones, while in the absence of growth stimulation effect glial cells can take part in the axons growth. It is supposed that the glial cells are capable of playing the role of the cells, which direct axons growth in the absence of influence of specific target factor.
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Museridze
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D000818:Animals; D001369:Axons / Q000648:ultrastructure*; D002642:Chick Embryo; D003470:Culture Media; D009132:Muscles / Q000166:cytology; D009457:Neuroglia / Q000166:cytology; D009924:Organ Culture Techniques; D013116:Spinal Cord / Q000166:cytology*
D003470:Culture Media
Rost aksonov v organotipicheskoĭ kul'ture spinnogo mozga.