title: [Experimental positional nystagmus induced by argon laser irradiation to the oval window].
abstract: Experimental positional nystagmus (EPN) similar to benign paroxysmal positional nystagmus (BPPN) was induced in 8 of 20 rabbits by argon laser irradiation to the footplate. The power of the argon beam used was 2.0 watts and irradiation time was 1 or 2 sec. EPN and BPPN showed the following similarities maintained (1) When the head was maintained in the affected ear down position and the head positioned from the sitting to the supine position nystagmus directed to the affected ear or vertical nystagmus corresponding to rotatory nystagmus in man were provoked. (2) Delayed onset for provocation of nystagmus. (3) Limited duration. (4) Fatigability. (5) The direction of nystagmus was reversed when the head returned to the initial position (in two rabbits). Histological examination of the temporal bones showed separation of otoconia from the otolithic membrane of the saccule and bleeding in the saccule in both conditions. No lesions in the utricle and semicircular canals were evident. It was assumed that ablation of otoconia of the saccule causes this experimental positional nystagmus.
authors.affiliation: Department of Otolaryngology, School of Medicine, Nagasaki University.
authors.forename: K
authors.initials: K
authors.lastname: Shigeno
authors.forename: H
authors.initials: H
authors.lastname: Kumagami
authors.forename: T
authors.initials: T
authors.lastname: Noda
authors.forename: T
authors.initials: T
authors.lastname: Egami
authors.forename: S
authors.initials: S
authors.lastname: Nakajima
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D006257:Head; D007834:Lasers; D009759:Nystagmus, Pathologic / Q000209:etiology*; D010046:Oval Window, Ear / Q000528:radiation effects*; D011187:Posture; D011817:Rabbits; D012444:Saccule and Utricle / Q000473:pathology / Q000528:radiation effects; D014722:Vestibule, Labyrinth / Q000528:radiation effects*