title: [Severe tetanus and intrathecal baclofen].
abstract: Case report of a 48-year-old man with a severe tetanus managed with conventional treatment associated with subarachnoid administration of baclofen. An epidural catheter was placed in spinal fluid at level L3-L4. Two injections of 1 mg baclofen at an interval of 1 hour amended the spasticity. Thereafter the treatment was maintained with a continuous infusion of 2 mg.24 h-1 over 20 days which resulted in an efficient control of spasticity. The final outcome was favourable.
authors.affiliation: Service de Réanimation, Hôpital Principal, Dakar, Sénégal.
authors.forename: J M
authors.initials: JM
authors.lastname: Saissy
authors.forename: O
authors.initials: O
authors.lastname: Raux
authors.forename: R
authors.initials: R
authors.lastname: Gohard
authors.forename: B
authors.initials: B
authors.lastname: Diatta
mesh_terms: D001418:Baclofen / Q000008:administration & dosage / Q000627:therapeutic use*; D003402:Creatine Kinase / Q000097:blood; D006801:Humans; D007278:Injections, Spinal; D008297:Male; D008875:Middle Aged; D013742:Tetanus / Q000188:drug therapy*
chemical_list: D003402:Creatine Kinase; D001418:Baclofen
vernacular_title: Tétanos sévère et baclofène intrathécal.