[Short-term antibiotic prophylaxis in surgery. Our experience with the use of piperacillin in 261 patients].
Personal experience of short-term chemoprophylaxis with piperacillin in 261 consecutive "clean" and "non-contaminating" operations is reported. Piperacillin was employed in a dose of 2 g i.m. every 8 hours for a total of 48 hours, the first administration being carried out at the same time as pre-anaesthesia. Results of the study showed 8 cases (3.06%) of hyperpyrexia (greater than 38.5 C for at least 3 days) and no cases of wound, bronchopulmonary or urinary infection or systemic sepsis were encountered. It is concluded that the use of piperacillin enables "clean" and "non-contaminating" general surgery interventions to be carried out almost without risk of infection.
Bonatti
P L
PL
Istituto di Clinica Chirurgica Generale, Università Cattolica del Sacro Cuore, Roma.
Destito
C
C
Venuto
V
V
Wiel Marin
A
A
D001424:Bacterial Infections / Q000517:prevention & control*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D010878:Piperacillin / Q000008:administration & dosage / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000517:prevention & control*; D011229:Preanesthetic Medication
D010878:Piperacillin
La profilassi antibiotica "short term" in chirurgia. Nostra esperienza con l'uso della piperacillina in 261 pazienti.