[Changes in several characteristics of the erythrocyte membrane and erythrocyte structure in severe burns in animal experiments].
It is determined in experiments on rats that the IIIB degree thermal injuries of 20% of the total body surface significantly reduce the erythrocytic membrane's resistance and cause the production of peroxides in 15 minutes after trauma. Simultaneously the electrical properties begin to change. The structure of erythrocytes is also altered. In 30 minutes post injury these alterations are in progress, but in 60 minutes they are less expressed. The structure of the erythrocytes is significantly altered. The authors consider that the influence of membranotoxic factors--the products of free radicals' reactions and phospholipases--is accounted for all noticed alterations.
Zaets
T L
TL
Lavrov
V A
VA
Marchuk
A I
AI
Nosova
I M
IM
D000818:Animals; D002056:Burns / Q000097:blood* / Q000378:metabolism; D004910:Erythrocyte Membrane / Q000378:metabolism* / Q000502:physiology; D004912:Erythrocytes / Q000166:cytology* / Q000378:metabolism; D005609:Free Radicals; D008297:Male; D010545:Peroxides / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D005609:Free Radicals; D010545:Peroxides
Izmenenie nekotorykh svoĭstv éritrotsitnoĭ membrany i struktury éritrotsitov pri tiazhelykh ozhogakh v éksperimente.