title: Massive, solitary, intrahepatic, extramedullary hematopoietic tumor in thalassemia.
abstract: Diffuse compensatory extramedullary hematopoiesis is well known to involve the spleen and liver in certain hematologic disorders. Hematopoietic tumor masses occasionally form and usually occur paraspinally in the posterior mediastinum. A 31-year-old patient with thalassemia is described with a massive, solitary, intrahepatic hematopoietic tumor and a smaller one in the posterior mediastinum. Review of the literature indicates that presentation as a large, focal liver lesion is unique. The implications and differential diagnosis are discussed.
authors.affiliation: Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin.
authors.forename: G
authors.initials: G
authors.lastname: Dewar
authors.forename: N W
authors.initials: NW
authors.lastname: Leung
authors.forename: H K
authors.initials: HK
authors.lastname: Ng
authors.forename: M
authors.initials: M
authors.lastname: Bradley
authors.forename: A K
authors.initials: AK
authors.lastname: Li
mesh_terms: D000328:Adult; D001706:Biopsy; D005260:Female; D006410:Hematopoiesis; D006801:Humans; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology; D013789:Thalassemia / Q000150:complications*; D014057:Tomography, X-Ray Computed