title: [Thrombolytic treatment of myocardial infarction at the prehospital and hospital stage].
abstract: Thrombolytic therapy was performed in 59 patients within the first hours of myocardial infarction. Twenty three patients (Group 1) were given streptokinase (SK) by an emergency team, 36 patients (Group 2) received SK following coronary angiography. In Group 1, SK was initiated earlier (p less than 0.001) than in Group 2. In Group 1 there was no coronary artery occlusion in the appropriate site of myocardial infarction in 86% of the patients. In Group 2, coronary occlusion was detected in 88% reperfusion, in 50% of the cases. Severe overall and regional left ventricular contractility abnormalities were found within the first month of the disease. The incidence of complications is the same in the two groups. High efficiency and relatively safe of thrombolytic therapy in the prehospital period makes this method particularly promising for practical medicine.
authors.forename: I I
authors.initials: II
authors.lastname: Staroverov
authors.forename: I A
authors.initials: IA
authors.lastname: Tagieva
authors.forename: E V
authors.initials: EV
authors.lastname: Pomerantsev
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Ovasapian
authors.forename: B N
authors.initials: BN
authors.lastname: Dorogun
authors.forename: V P
authors.initials: VP
authors.lastname: Serov
authors.forename: A T
authors.initials: AT
authors.lastname: Puchkov
authors.forename: S L
authors.initials: SL
authors.lastname: Abramov
authors.forename: A N
authors.initials: AN
authors.lastname: Plotnikov
authors.forename: A P
authors.initials: AP
authors.lastname: Savchenko
mesh_terms: D000328:Adult; D000368:Aged; D004359:Drug Therapy, Combination; D004632:Emergency Medical Services / Q000458:organization & administration*; D005392:First Aid; D006493:Heparin / Q000008:administration & dosage*; D006760:Hospitalization; D006801:Humans; D007262:Infusions, Intravenous; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D011239:Prednisolone / Q000008:administration & dosage*; D013300:Streptokinase / Q000008:administration & dosage*; D015912:Thrombolytic Therapy; D013997:Time Factors
chemical_list: D006493:Heparin; D011239:Prednisolone; D013300:Streptokinase
vernacular_title: Tromboliticheskaia terapiia pri infarkte miokarda na dogospital'nom i statsionarnom étapakh.