[Enzymatic lysis of staphylococci in relation to their species and strain properties].
The lysoenzyme preparation from Streptomyces recifensis subsp. lyticus 2435 had a marked lytic activity against staphylococci of different species, spectra and antibiotic sensitivity. Certain strain differences of the cells in the population could be easily eliminated with increasing the dose. The preparation is a complex of lytic enzymes with high antimicrobial activity. It was concluded that it could be considered as a potentially promising chemotherapeutic agent for treatment of staphylococcal infections.
Babenko
Iu S
IuS
Ghilomedova
L E
LE
Kukushkina
N V
NV
D001433:Bacteriolysis / Q000187:drug effects* / Q000502:physiology; D003470:Culture Media; D004352:Drug Resistance, Microbial; D066298:In Vitro Techniques; D009113:Muramidase / Q000494:pharmacology*; D013045:Species Specificity; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000502:physiology; D013212:Staphylococcus epidermidis / Q000187:drug effects* / Q000502:physiology; D013291:Streptococcus / Q000201:enzymology*; D014020:Tissue Extracts / Q000494:pharmacology
D003470:Culture Media; D014020:Tissue Extracts; D009113:Muramidase
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