title: [Cellular kinetics and the nuclear ploidy pattern in relation to the gross pathological classification and location of advanced colorectal cancers as analyzed by DNA-RNA cytofluorometry].
abstract: Correlated studies on the cellular kinetics in association with the nuclear ploidy pattern and the pathological morphology of advanced colorectal cancers have been carried out using DNA-RNA cytofluorometry with an AO stain. The results showed that advanced colorectal cancers could be separated into the 3 distinct groups that follow: group I, involving a diploid cell population; group II, a polyploid cell population; and, group II', an aneuploid cell population. The group I type was located in the entire colorectal region, where as groups II and II', were in the sigmoid and rectum. Three groups were mostly Borrmann type 3 cancers, and the gross pathological classification was not found to be related to the ploidy pattern.
authors.affiliation: Dept. of 1st Pathology, Kyoto Prefectural Univ. of Med.
authors.forename: T
authors.initials: T
authors.lastname: Hashimoto
authors.forename: N
authors.initials: N
authors.lastname: Morotomi
authors.forename: H
authors.initials: H
authors.lastname: Itoi
authors.forename: Y
authors.initials: Y
authors.lastname: Urata
authors.forename: K
authors.initials: K
authors.lastname: Ueda
authors.forename: E
authors.initials: E
authors.lastname: Konishi
authors.forename: S
authors.initials: S
authors.lastname: Yagi
authors.forename: Y
authors.initials: Y
authors.lastname: Tsuchihashi
authors.forename: M
authors.initials: M
authors.lastname: Kodama
authors.forename: T
authors.initials: T
authors.lastname: Ashihara
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000782:Aneuploidy; D002453:Cell Cycle; D002467:Cell Nucleus / Q000032:analysis; D015179:Colorectal Neoplasms / Q000032:analysis / Q000235:genetics / Q000473:pathology*; D004273:DNA, Neoplasm / Q000032:analysis*; D004171:Diploidy; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D008297:Male; D008875:Middle Aged; D011003:Ploidies; D011123:Polyploidy; D012334:RNA, Neoplasm / Q000032:analysis*
chemical_list: D004273:DNA, Neoplasm; D012334:RNA, Neoplasm