Lack of hemostatic effects of adult and suckling cat salivary gland heteropolysaccharides on blood coagulation.
Like other mammalian salivary glands, the cat submandibular and parotid glands belonging to adult and growing subjects contain heteropolysaccharides with very heterogeneous composition. Such glycoconjugates were this time tested in humans at doses used previously showing anticoagulant properties in rodents and lagomorphs. But surprisingly, no anticoagulant effects could be detected consistently. In fact, neither thromboelastography, nor hemocoagulation screening tests were affected in a statistically significant manner.
Menghi
G
G
Dipartimento di Biologia Cellulare, Università di Camerino, Italy.
Lai
G
G
Piciotti
D
D
D000818:Animals; D000833:Animals, Suckling; D001777:Blood Coagulation / Q000187:drug effects*; D002415:Cats; D006001:Glycoconjugates / Q000032:analysis / Q000494:pharmacology*; D011134:Polysaccharides / Q000032:analysis / Q000494:pharmacology*; D012469:Salivary Glands / Q000032:analysis*
D006001:Glycoconjugates; D011134:Polysaccharides