title: R-banding and in situ hybridization localization of single copy genes on high resolution banded chromosomes.
abstract: A method to preserve high resolution R-bands on human lymphocyte chromosomes after in situ hybridization to 3H-labelled probes and autoradiography is presented. The technique was used to re-examine the location of the known oncogene N-myc. Due to the high resolution power of the present technique, this gene could be located to subband 2p24.1 in the human karyotype.
authors.affiliation: Institute of Anatomy and Cytology, Odense University, Denmark.
authors.forename: M
authors.initials: M
authors.lastname: Rønne
authors.forename: F
authors.initials: F
authors.lastname: Kirpekar
authors.forename: Y
authors.initials: Y
authors.lastname: Shibasaki
authors.forename: B S
authors.initials: BS
authors.lastname: Poulsen
authors.forename: K
authors.initials: K
authors.lastname: Kristiansen
mesh_terms: D002871:Chromosome Banding / Q000379:methods*; D002874:Chromosome Mapping; D002889:Chromosomes, Human, Pair 2; D006801:Humans; D009693:Nucleic Acid Hybridization; D009857:Oncogenes; D014960:X Chromosome