Myelofibrosis discovered after diagnosis of Sweet's syndrome.
Multiple edematous plaques and nodules suddenly developed on the face and neck of a 26-year-old man whose physical examination was said to be normal Because the patient's condition fulfilled the diagnostic criteria of Sweet's syndrome, a further general medical examination and hematologic evaluation were performed. Extensive myelofibrosis was revealed by bone marrow biopsy. This case supports the belief that Sweet's syndrome is a reactive phenomenon. Because myelofibrosis was discovered in this patient after Sweet's syndrome was diagnosed, the importance of having the diagnostic criteria of Sweet's syndrome is emphasized. Careful systemic evaluation is indicated, especially when cutaneous lesions are severe or hematologic values are abnormal.
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W P
WP
Department of Dermatology, Mayo Clinic, Rochester, Minnesota 55905.
Alegre
V A
VA
White
W L
WL
D000328:Adult; D005334:Fever; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000473:pathology*; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use; D055728:Primary Myelofibrosis / Q000150:complications*; D012871:Skin Diseases / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D013577:Syndrome
D011241:Prednisone