Granular corneal dystrophy Groenouw type I. A report of a probable homozygous patient.
A case of severe granular corneal dystrophy is described. The patient, who is most probably homozygous for the dominantly inherited dystrophy gene, is the product of a first cousin marriage with both parents mildly affected by the same dystrophy. The case report describes an early onset and a severe course with two grafts in each eye before the age of 17. Pictures of the clinical appearance, histology and transmission electronmicroscopy are shown.
Møller
H U
HU
Department of Ophthalmology, University Hospital, Arhus, Denmark.
Ridgway
A E
AE
D003317:Corneal Dystrophies, Hereditary / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D003318:Corneal Opacity / Q000473:pathology; D016039:Corneal Transplantation; D005260:Female; D006720:Homozygote; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D014792:Visual Acuity