title: Brainstem acoustic evoked responses: maturational aspects from cochlea to midbrain.
abstract: BAEPs were recorded from 92 healthy children with a gestational age of 35 weeks up to 16 years. The maturation kinetic of I-III and I-V interpeak latency can well be approximated by the exponential regressions I-V : y = 0.9588 x e -0.9215 x x + 3.9728; r = 0.87; I-III : y = 0.6182 x e -1.1737 x x + 2.1759; r = 0.81; Adult values are reached by about two years of life. In contrast to this immaturity of the central auditory pathways the slopes of latency--intensity functions of waves I and V show no significant differences between premature infants and neonates versus older children over three years. Caused by the prolonged I-V IPL wave V latency is about 1 ms longer in the first group, whereas wave I is only slightly prolonged (0.2 ms) within the first three months of life.
authors.affiliation: Department of Neuropediatrics, Children's Hospital, University of Erlangen.
authors.forename: H
authors.initials: H
authors.lastname: Lauffer
authors.forename: D
authors.initials: D
authors.lastname: Wenzel
mesh_terms: D000161:Acoustic Stimulation; D000293:Adolescent; D000375:Aging / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D003051:Cochlea / Q000254:growth & development / Q000502:physiology*; D005072:Evoked Potentials, Auditory; D006801:Humans; D007223:Infant; D008636:Mesencephalon / Q000254:growth & development / Q000502:physiology*