The mouse mutation ulnaless on chromosome 2.
The dominant skeletal mutation ulnaless (Ul) in the mouse causes extreme reduction of the radius and ulna and deformities of the tibia and fibula. Penetrance appears to be complete, but the homozygote is not known, as heterozygous males do not breed. We report the linkage of the Ul gene on Chromosome 2, 18 cM proximal to pallid (pa), and describe its phenotypic effects.
Davisson
M T
MT
Jackson Laboratory, Bar Harbor, Maine 04609.
Cattanach
B M
BM
D000818:Animals; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D005260:Female; D008040:Genetic Linkage; D006579:Heterozygote; D017880:Limb Deformities, Congenital; D008297:Male; D051379:Mice / Q000235:genetics*; D008815:Mice, Inbred Strains; D009154:Mutation; D010641:Phenotype; D012098:Reproduction