title: Zygote intrafallopian transfer with "donor rescue": a new option for severe male factor infertility.
abstract: Clinical pregnancies have been initiated by ZIFT using zygotes produced by reinsemination of oocytes with donor sperm ("donor rescue") after an initial 15- to 20-hour exposure to husband's sperm. A total of 54 oocytes from four couples experiencing failed fertilization by husband's sperm were reinseminated with donor sperm, resulting in 38 zygotes (70.4% fertilization). Four zygotes were transferred during ZIFT in each case and resulted in two (50%) continuing pregnancies. Additional zygotes from donor reinsemination were cryopreserved for each couple. Donor rescue expands the utility of ZIFT as a treatment for male factor infertility.
authors.affiliation: Southwest Texas Methodist Hospital, San Antonio.
authors.forename: T B
authors.initials: TB
authors.lastname: Pool
authors.forename: J E
authors.initials: JE
authors.lastname: Martin
authors.forename: L R
authors.initials: LR
authors.lastname: Ellsworth
authors.forename: J B
authors.initials: JB
authors.lastname: Perez
authors.forename: S H
authors.initials: SH
authors.lastname: Atiee
mesh_terms: D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007248:Infertility, Male / Q000628:therapy*; D007315:Insemination, Artificial; D007316:Insemination, Artificial, Heterologous; D007317:Insemination, Artificial, Homologous; D008297:Male