title: Cryptococcal choroiditis.
abstract: Two patients with acquired immune deficiency syndrome presented with headaches and fevers. A diagnosis of cryptococcal meningitis was made by lumbar puncture and elevated cryptococcal antigens. Complaints of decreased vision in both patients led to the diagnosis of optic disc edema and cryptococcal choroiditis with yellow-white choroidal infiltrates noted in both eyes of the two patients. Systemic treatment with amphotericin B and 5' flucytosine led to resolution of the choroidal infiltrates. Late visual acuity loss was believed to be secondary to optic atrophy.
authors.affiliation: Department of Ophthalmology, Medical College of Virginia, Virginia Commonwealth University, Richmond.
authors.forename: M D
authors.initials: MD
authors.lastname: Carney
authors.forename: J L
authors.initials: JL
authors.lastname: Combs
authors.forename: W
authors.initials: W
authors.lastname: Waschler
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000946:Antigens, Fungal / Q000134:cerebrospinal fluid; D002833:Choroiditis / Q000150:complications* / Q000188:drug therapy; D003453:Cryptococcosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D015821:Eye Infections, Fungal / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005437:Flucytosine / Q000627:therapeutic use; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D010211:Papilledema / Q000209:etiology; D014792:Visual Acuity
chemical_list: D000946:Antigens, Fungal; D000666:Amphotericin B; D005437:Flucytosine