[The behavior of plutonium in the body of rats after its intragastric administration as its tributyl phosphate complex in a mixture of organic diluents].
Dilution of tribytylphosphate with normal paraffin, hexachlorbutadiene and trichlorobenzene does not change the pattern of plutonium distribution, but introduces some peculiarities in its dynamics. The lowest resorption of the radio element from the gastrointestinal tract was noted in the case of normal paraffins which, together with their low toxicity, makes this diluent preferable.
Zhuravleva
A K
AK
D000042:Absorption; D000284:Administration, Oral; D000818:Animals; D002070:Butadienes / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology; D002722:Chlorobenzenes / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology; D005260:Female; D009942:Organometallic Compounds / Q000008:administration & dosage / Q000493:pharmacokinetics*; D010755:Organophosphates / Q000008:administration & dosage / Q000493:pharmacokinetics*; D009943:Organophosphorus Compounds / Q000008:administration & dosage / Q000493:pharmacokinetics*; D010232:Paraffin / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology; D011005:Plutonium / Q000008:administration & dosage / Q000493:pharmacokinetics*; D051381:Rats; D011919:Rats, Inbred Strains; D012997:Solvents / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000494:pharmacology; D013270:Stomach; D013997:Time Factors; D014018:Tissue Distribution / Q000187:drug effects
D002070:Butadienes; D002722:Chlorobenzenes; D009942:Organometallic Compounds; D010755:Organophosphates; D009943:Organophosphorus Compounds; D012997:Solvents; C038503:plutonium tri-n-butylphosphate complex; C036720:trichlorobenzene; D011005:Plutonium; D010232:Paraffin; C001335:hexachlorobutadiene
Povedenie plutoniia v organizme krys posle vnutrizheludochnogo vvedeniia ego kompleksa s tribulitfosfatom v smesi s organicheskimi razbaviteliami.