Survival of BSC-1 cells through the maintenance of cell volume brought about by epidermal growth factor depends on attachment to the substratum.
Addition of epidermal growth factor to culture medium without calf serum suppressed the increase in cell volume and then enhanced the survival of BSC-1 cells attached to culture dishes. However, these effects of epidermal growth factor were not observed in the case of cells on dishes coated with heat-denatured bovine serum albumin.
Shiba
Y
Y
Department of Oral Physiology, Hiroshima University School of Dentistry, Japan.
Kanno
Y
Y
D000818:Animals; D002448:Cell Adhesion; D002470:Cell Survival; D002478:Cells, Cultured; D002522:Chlorocebus aethiops; D003470:Culture Media; D004815:Epidermal Growth Factor / Q000494:pharmacology*; D005346:Fibroblast Growth Factors / Q000494:pharmacology; D007668:Kidney / Q000166:cytology*; D010982:Platelet-Derived Growth Factor / Q000494:pharmacology; D012710:Serum Albumin, Bovine / Q000494:pharmacology; D015291:Transforming Growth Factors / Q000494:pharmacology
D003470:Culture Media; D010982:Platelet-Derived Growth Factor; D012710:Serum Albumin, Bovine; D005346:Fibroblast Growth Factors; D004815:Epidermal Growth Factor; D015291:Transforming Growth Factors