The Rett syndrome related to fragile X(P22) in caffeine-induced lymphocyte culture.
Chromosome analyses of lymphocytes cultured in a medium supplemented with caffeine showed a significantly higher frequency of fragile X(p22) in 13 girls with the Rett syndrome (RS) than in 9 healthy controls (p less than 0.05).
Wahlström
J
J
Department of Psychiatry III, East Hospital, Göteborg, Sweden.
Witt-Engerström
I
I
Mellquist
L
L
Anvret
M
M
Oden
A
A
D000293:Adolescent; D000328:Adult; D002110:Caffeine / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D002648:Child; D002675:Child, Preschool; D005260:Female; D005600:Fragile X Syndrome / Q000235:genetics*; D006801:Humans; D008214:Lymphocytes / Q000166:cytology* / Q000187:drug effects; D015518:Rett Syndrome / Q000235:genetics*; D012729:Sex Chromosome Aberrations / Q000235:genetics*
D002110:Caffeine