A monoclonal antibody to platelet glycoprotein IIb induces aggregation of platelet rich plasma.
The monoclonal antibody (MAb) GAP 5.9 directed against platelet glycoprotein IIb is described. This MAb is able to induce aggregation of platelet rich plasma in the absence of further stimuli and likely recognizes a glycoprotein epitope not closely related to calcium binding sites on the molecule.
Perutelli
P
P
Divisione di Ematologia e Oncologia, Istituto G. Gaslini, Genova, Italy.
Marchese
P
P
Mori
P G
PG
D000911:Antibodies, Monoclonal / Q000276:immunology*; D006801:Humans; D010974:Platelet Aggregation / Q000276:immunology*; D010980:Platelet Membrane Glycoproteins / Q000276:immunology*
D000911:Antibodies, Monoclonal; D010980:Platelet Membrane Glycoproteins