Acute, rapidly progressive renal failure with simultaneous use of amphotericin B and pentamidine.
We report four cases of acute reversible renal failure in patients with acquired immune deficiency syndrome who received both amphotericin B (for systemic mycoses) and pentamidine isethionate (for Pneumocystis carinii pneumonia). The concurrent use of amphotericin B with either inhaled pentamidine or trimethoprim-sulfamethoxazole did not cause significant renal impairment.
Antoniskis
D
D
Los Angeles County-University of Southern California Medical Center 90033.
Larsen
R A
RA
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy; D058186:Acute Kidney Injury / Q000139:chemically induced*; D000328:Adult; D000666:Amphotericin B / Q000009:adverse effects*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D009181:Mycoses / Q000188:drug therapy; D010419:Pentamidine / Q000009:adverse effects*; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy
D010419:Pentamidine; D000666:Amphotericin B