Beta-glucan and pectin derivatives stimulate prolactin secretion from hypophysis in vitro.
Previous work has shown that various plant extracts administered to animals stimulate milk protein synthesis through the secretion of prolactin. It has also been shown that beta-glucan and pectin are the active molecules capable of stimulating prolactin release in vivo after intravenous injections. In this work, it is shown that beta-glucan and several pectin derivatives are able to stimulate prolactin secretion from hypophysis fragments incubated for 2 hr in a synthetic medium.
Sepehri
H
H
Unite de Différenciation Cellulaire, Institute National de la Recherche Agronomique, Jouy-en-Josas, France.
Renard
C
C
Houdebine
L M
LM
D000818:Animals; D003470:Culture Media; D046508:Culture Techniques; D005260:Female; D005936:Glucans / Q000494:pharmacology*; D010368:Pectins / Q000494:pharmacology*; D010902:Pituitary Gland / Q000187:drug effects* / Q000378:metabolism; D010936:Plant Extracts / Q000494:pharmacology; D011388:Prolactin / Q000378:metabolism*; D012756:Sheep
D003470:Culture Media; D005936:Glucans; D010936:Plant Extracts; D010368:Pectins; D011388:Prolactin