title: [Chemotherapy of disseminated forms of breast cancer using platinum derivatives].
abstract: Platinum-based combination chemotherapy regimens (CAP or CMF + cisplatin) were used for the treatment of disseminated breast cancer. Response rate for the CAP regimen was 47.5%. The most frequent side-effects were nausea, vomiting, nephrotoxicity and myelosuppression. Relationship between survival and response was identified.
authors.forename: V A
authors.initials: VA
authors.lastname: Gorbunova
authors.forename: N B
authors.initials: NB
authors.lastname: Trofimova
authors.forename: L V
authors.initials: LV
authors.lastname: Manziuk
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000401:mortality; D002945:Cisplatin / Q000008:administration & dosage*; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010752:Phosphoramide Mustards / Q000008:administration & dosage; D013997:Time Factors
chemical_list: D010752:Phosphoramide Mustards; D004317:Doxorubicin; D003520:Cyclophosphamide; D002945:Cisplatin; D005472:Fluorouracil; D008727:Methotrexate
vernacular_title: Khimioterapiia rasprostranennykh form raka molochnoĭ zhelezy s ispol'zovaniem proizvodnykh platiny.