Use of rhodamine 123 in the treatment of the Pollard III rat prostate adenocarcinoma.
Significant destruction of the Pollard III rat prostate adenocarcinoma was achieved by treatment with rhodamine 123 at a dosage of 15 mg/kg every other day for 33 to 38 days. Injection of tumor remnants into untreated animals produced no tumor regrowth. Our data have demonstrated rhodamine 123 to be a significant drug for the management of the very aggressive Pollard III tumor.
Arcadi
J A
JA
Cancer Research Laboratory, Whittier College, CA 90608.
D000230:Adenocarcinoma / Q000188:drug therapy*; D000728:Androgens / Q000502:physiology; D000818:Animals; D008297:Male; D009376:Neoplasms, Hormone-Dependent / Q000188:drug therapy; D011471:Prostatic Neoplasms / Q000188:drug therapy*; D051381:Rats; D020112:Rhodamine 123; D012235:Rhodamines / Q000627:therapeutic use*; D014966:Xanthenes / Q000627:therapeutic use*
D000728:Androgens; D012235:Rhodamines; D014966:Xanthenes; D020112:Rhodamine 123