title: Use of rhodamine 123 in the treatment of the Pollard III rat prostate adenocarcinoma.
abstract: Significant destruction of the Pollard III rat prostate adenocarcinoma was achieved by treatment with rhodamine 123 at a dosage of 15 mg/kg every other day for 33 to 38 days. Injection of tumor remnants into untreated animals produced no tumor regrowth. Our data have demonstrated rhodamine 123 to be a significant drug for the management of the very aggressive Pollard III tumor.
authors.affiliation: Cancer Research Laboratory, Whittier College, CA 90608.
authors.forename: J A
authors.initials: JA
authors.lastname: Arcadi
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy*; D000728:Androgens / Q000502:physiology; D000818:Animals; D008297:Male; D009376:Neoplasms, Hormone-Dependent / Q000188:drug therapy; D011471:Prostatic Neoplasms / Q000188:drug therapy*; D051381:Rats; D020112:Rhodamine 123; D012235:Rhodamines / Q000627:therapeutic use*; D014966:Xanthenes / Q000627:therapeutic use*
chemical_list: D000728:Androgens; D012235:Rhodamines; D014966:Xanthenes; D020112:Rhodamine 123