title: One pot solution synthesis of cyclic oligodeoxyribonucleotides.
abstract: Several cyclic oligodeoxynucleotides with different base composition and size have been prepared from 5',3'-unprotected linear precursors, using a bifunctional phosphorylating reagent. The final deprotected oligomers have been characterized by 1H- and 31P-NMR. The present procedure is particularly useful for millimolar scale syntheses.
authors.affiliation: ICoCEA-CNR, Bologna, Italy.
authors.forename: M L
authors.initials: ML
authors.lastname: Capobianco
authors.forename: A
authors.initials: A
authors.lastname: Carcuro
authors.forename: L
authors.initials: L
authors.lastname: Tondelli
authors.forename: A
authors.initials: A
authors.lastname: Garbesi
authors.forename: G M
authors.initials: GM
authors.lastname: Bonora
mesh_terms: D001483:Base Sequence; D009682:Magnetic Resonance Spectroscopy; D008722:Methods; D015394:Molecular Structure; D009712:Nucleotides, Cyclic / Q000138:chemical synthesis* / Q000302:isolation & purification; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis* / Q000302:isolation & purification; D010766:Phosphorylation
chemical_list: D009712:Nucleotides, Cyclic; D009838:Oligodeoxyribonucleotides