[Renal involvement in rheumatoid polyarthritis].
Urinary disorders were investigated in 162 patients with specific or standard rheumatoid disease, over a period of 5 years. 43 patients presented disturbances of the urinary laboratory tests, or 26.5 p. cent and 17 of them underwent a renal needle-biopsy. The findings were as follows: 11 isolated proteinurias, iatrogenic and reversible when the treatment in question was discontinued (gold salts, D-penicillamine), 13 microscopic hematurias, 3 isolated leucocyturias, 3 combinations hematuria-leucocyturia, 3 combinations hematuria-leucocyturia-proteinuria, 6 nephrotic syndromes including 5 of iatrogenic origin, 4 isolated renal failures. The most interesting discussion concerns microscopic hematurias. Besides the standard lesions of extra-membranous glomerulonephritis, amyloidosis and interstitial nephritis, 50 p. cent of the renal histologic examinations corresponded to lesions of mesangial glomerulonephritis. This lesion seems unrelated to long-term treatments and could be encouraged by the chronic inflammatory condition of the rheumatoid disease.
Cantagrel
A
A
Clinique de Rhumatologie, CHU de Purpan, Toulouse.
Pourrat
J
J
Fournié
B
B
Conte
J J
JJ
Fournié
A
A
D000293:Adolescent; D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy / Q000652:urine; D005260:Female; D015432:Glomerulonephritis, Membranoproliferative / Q000209:etiology / Q000473:pathology; D006417:Hematuria / Q000209:etiology; D006801:Humans; D007668:Kidney / Q000473:pathology; D007674:Kidney Diseases / Q000139:chemically induced / Q000209:etiology* / Q000473:pathology; D007964:Leukocytosis / Q000209:etiology / Q000652:urine; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000209:etiology; D011507:Proteinuria / Q000209:etiology; D012189:Retrospective Studies; D013997:Time Factors
L'atteinte rénale au cours de la polyarthrite rhumatoïde.