[Role of intracellular contact interactions in macrophage reaction to activators containing and not containing the Arg-Gly-Asp sequence].
It was found out that macrophage superoxide production is stimulated by intracellular contacts. The high level of the nitro-blue tetrazolium salt reduction in individual cells non-contacting with others is reached when using fibronectin or serum-opsonized zymosan but not phorbol myristate acetate or chemotactic formyl-peptide as activators. The reaction enhancement in non-contacting macrophages stimulated with phorbol ester occurs in the presence of Arg-Gly-Asp-Ser synthetic peptide.
Zemskov
V M
VM
Subbotin
S M
SM
Skliarov
L Iu
LIu
Bykova
I V
IV
Nikolaev
A Iu
AIu
D000595:Amino Acid Sequence; D000818:Animals; D001120:Arginine; D001224:Aspartic Acid; D002450:Cell Communication; D005353:Fibronectins / Q000494:pharmacology; D005998:Glycine; D008264:Macrophages / Q000187:drug effects*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D015054:Zymosan / Q000494:pharmacology
D005353:Fibronectins; D001224:Aspartic Acid; D015054:Zymosan; D001120:Arginine; D013755:Tetradecanoylphorbol Acetate; D005998:Glycine
Rol' mezhkletochnykh kontaktnykh vzaimodeĭstviĭ pri reaktsii makrofagov na aktivatory, soderzhashchie i ne soderzhashchie posledovatel'nost' ARG-CLY-ASP.