Effects of microwave irradiation on blood flow in the dog hindlimb.
Physiotherapeutic doses of microwave irradiation to the hindlimb of the anaesthetized dog increased the temperature in the underlying skin and muscle by 5-6 degrees C and, after a latency of 2-8 min, heart rate, blood pressure and femoral conductance all increased. The conductance increase was predominantly in the paw. At this time plasma catecholamine levels were elevated above resting values. At the conclusion of irradiation, heart rate and blood pressure rapidly returned to basal levels, but there was a sustained increase in femoral conductance which was mainly in the leg. The results are discussed in terms of the likely mechanisms underlying the effects of microwave irradiation on limb blood flow and compared with those obtained with direct heating of arterial blood and limb tissue in the accompanying paper.
McMeeken
J M
JM
Department of Physiology, University of Melbourne Medical Centre, Victoria, Australia.
Bell
C
C
D000818:Animals; D001783:Blood Flow Velocity / Q000528:radiation effects*; D001794:Blood Pressure / Q000502:physiology / Q000528:radiation effects; D001831:Body Temperature / Q000502:physiology / Q000528:radiation effects; D002395:Catecholamines / Q000097:blood; D004285:Dogs; D005260:Female; D005263:Femoral Artery; D006339:Heart Rate / Q000502:physiology / Q000528:radiation effects; D006614:Hindlimb / Q000098:blood supply; D006979:Hyperthermia, Induced / Q000379:methods*; D008297:Male; D008872:Microwaves; D012881:Skin Temperature / Q000502:physiology / Q000528:radiation effects
D002395:Catecholamines