[Cystic fibrosis: choices of treatment of respiratory manifestations (except Pseudomonas aeruginosa infections)].
A knowledge of the natural history of cystic fibrosis is the basis for a treatment which, so far, has only been symptomatic. The three fundamental elements of our therapeutic possibilities are: prevention and treatment of bronchial obstruction, administration of antibiotics active against staphylococci and Haemophilus influenza (Pseudomonas aeruginosa infections will be dealt with in another article of this journal), and control of bronchial inflammatory processes. Some complications of cystic fibrosis regarded as serious are no longer beyond our resources. Many works of fundamental research are needed, concerning the local conditions that are necessary to the selective implantation and the development of Staphylococcus aureus in the lung, and the virus Staphylococcus and Staphylococcus-Pseudomonas relations. The real hope of an absolute treatment justifies the new, aggressive therapeutic approach but the precise indications of an antistaphylococcal treatment must still be evaluated carefully. Finally, the complexity of a treatment which must constantly be adjusted is one of the reasons for the existence of "specialized consultations", the organization of which is summarized.
Gilly
R
R
Clinique médicale infantile A, centre hospitalier Lyon Sud, Pierre-Bénite.
Bellon
G
G
D000402:Airway Obstruction / Q000209:etiology / Q000517:prevention & control / Q000628:therapy; D001991:Bronchitis / Q000150:complications / Q000209:etiology / Q000628:therapy*; D003550:Cystic Fibrosis / Q000150:complications* / Q000503:physiopathology; D006801:Humans
Mucoviscidose: abord du traitement des manifestations respiratoires (infections à Pseudomonas aeruginosa exceptées).