[Effects of 4-methyluracil and carnosine on healing of skin wounds in rats].
In experiments in vivo and in vitro the authors studied antioxidative properties of 4-methyluracil and carnosine, their capacity to inhibit sex and accelerate healing of skin wounds. 4-methyluracil and carnosine discover almost the same capacity to decrease in the tissues of the wound and the blood serum in the formation of various intermediate products of free radical oxidation. Data are given on the study of the dynamics of wound healing after a 5-day treatment with equimolar quantities.
Silaeva
S A
SA
Guliaeva
N V
NV
Khatsernova
B Ia
BIa
Onufriev
M V
MV
Nikolaev
A Ia
AIa
D000818:Animals; D002336:Carnosine / Q000008:administration & dosage / Q000494:pharmacology*; D004151:Dipeptides / Q000494:pharmacology*; D005609:Free Radicals; D015227:Lipid Peroxidation / Q000187:drug effects; D051381:Rats; D012867:Skin / Q000293:injuries*; D013997:Time Factors; D014498:Uracil / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D014945:Wound Healing / Q000187:drug effects*
D004151:Dipeptides; D005609:Free Radicals; D014498:Uracil; C008378:6-methyluracil; D002336:Carnosine
Vliianie 4-metiluratsila i karnozina na zazhivlenie kozhnykh ran u krys.