title: Vaccination of free-ranging Pennsylvania raccoons (Procyon lotor) with inactivated rabies vaccine.
abstract: Thirty-nine free-ranging raccoons (Procyon lotor) in an endemic rabies area of Pennsylvania (USA) were vaccinated with a single intramuscular inoculation of commercial inactivated rabies virus vaccine, 17 June to 23 August 1987. Paired serum samples, pre- and postvaccination, were obtained from eight raccoons and were analyzed in vitro for rabies virus neutralizing antibody using a modified rapid fluorescent focus inhibition test. Seven of eight (88%) recaptured raccoons demonstrated seroconversion within 15 to 26 days of vaccination. At 1 yr postvaccination, three vaccinated raccoons were recaptured and challenged in captivity with street rabies virus, resulting in the death of two of three vaccinates and five of five unvaccinated control raccoons.
authors.affiliation: West Virginia Department of Natural Resources, French Creek 26218.
authors.forename: C L
authors.initials: CL
authors.lastname: Brown
authors.forename: C E
authors.initials: CE
authors.lastname: Rupprecht
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis*; D005260:Female; D007273:Injections, Intramuscular; D008297:Male; D009500:Neutralization Tests; D010414:Pennsylvania; D011818:Rabies / Q000517:prevention & control / Q000662:veterinary*; D011819:Rabies Vaccines / Q000008:administration & dosage / Q000276:immunology*; D011820:Rabies virus / Q000276:immunology*; D011821:Raccoons; D014611:Vaccination / Q000662:veterinary; D015164:Vaccines, Inactivated / Q000008:administration & dosage / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D011819:Rabies Vaccines; D015164:Vaccines, Inactivated