[Schönlein-Henoch purpura. A clinical study of 119 patients with special reference to unusual complications].
119 patients with Schönlein-Henoch purpura from 1 to 17 years were investigated. All patients had a rash, 76% joint affections, 76% gastrointestinal symptoms, 54% renal involvement, 17% of the boys orchitis, 2% intramuscular bleeding and 2% coagulation disorder. 1 boy showed perforation of the nasal septum, to our knowledge not described in Schönlein-Henoch purpura up to now. The mean age was 6.4 years. The seasonal peak was in October, 63% of our patients had a preceding infection, mostly of the upper respiratory tract, pointing to various infectious agents as a trigger of this disease. Patients with abdominal pain had a 4-fold, patients with bloody stools a 7.5-fold increased risk of renal involvement. 13/38 Patients had a serum albumin level below 3.5 g/dl that may have been caused either by renal or gastrointestinal losses.
Fischer
P J
PJ
Kinderklinik des Olgahospitals Stuttgart.
Hagge
W
W
Hecker
W
W
D000293:Adolescent; D001780:Blood Coagulation Tests; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D005767:Gastrointestinal Diseases / Q000209:etiology; D006801:Humans; D011695:IgA Vasculitis / Q000150:complications* / Q000175:diagnosis; D007223:Infant; D007674:Kidney Diseases / Q000209:etiology; D008297:Male; D012640:Seizures / Q000209:etiology
Purpura Schönlein-Henoch. Eine klinische Studie an 119 Patienten unter besonderer Berücksichtigung ungewöhnlicher Komplikationen.