title: Magnetic resonance imaging in Parkinson's disease.
abstract: Magnetic resonance imaging was utilized to examine changes in the pars compacta associated with Parkinson's disease. We found a reduction in average width of the pars compacta in advanced- but not early-stage patients. Conversely, a significant difference in width (right minus left) was observed in early- but not late-stage patients. Width asymmetry may be a sensitive magnetic resonance imaging indicator for the early detection of Parkinson's disease when there is a predominance of unilateral clinical symptoms.
authors.affiliation: Department of Neurology, Ohio State University College of Medicine, Columbus.
authors.forename: S J
authors.initials: SJ
authors.lastname: Huber
authors.forename: D W
authors.initials: DW
authors.lastname: Chakeres
authors.forename: G W
authors.initials: GW
authors.lastname: Paulson
authors.forename: R
authors.initials: R
authors.lastname: Khanna
mesh_terms: D000328:Adult; D000368:Aged; D001921:Brain / Q000473:pathology*; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000175:diagnosis*