title: Pseudohypertestosteronemia during danazol therapy. A case report.
abstract: Several steroid radioimmunoassay kits, particularly testosterone, cross-react with danazol, producing false elevations of serum steroid levels. A patient taking danazol simultaneously developed signs of virilization and an apparent 15-fold elevation in her serum testosterone. Discontinuation of danazol resulted in a prompt return to physical and biochemical normality.
authors.affiliation: Department of Obstetrics and Gynecology, Darnall Army Community Hospital, Fort Hood, Texas 76544-5063.
authors.forename: E J
authors.initials: EJ
authors.lastname: Miller
authors.forename: F H
authors.initials: FH
authors.lastname: Coleman
mesh_terms: D000328:Adult; D003613:Danazol / Q000009:adverse effects* / Q000378:metabolism; D004715:Endometriosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D011245:Pregnadienes / Q000009:adverse effects*; D011863:Radioimmunoassay; D013739:Testosterone / Q000097:blood*; D014594:Uterine Neoplasms / Q000188:drug therapy*; D014770:Virilism / Q000139:chemically induced*
chemical_list: D011245:Pregnadienes; D013739:Testosterone; D003613:Danazol