[Correlation of hereditary and environmental effects on external respiratory function and its changes during aging in twins].
The genetic-statistical analysis of 11 variables of the external respiration has been made in 90 twin pairs of the same sex divided into two age groups: 20-44 and 45-80 years. The following classification of indices of the lung ventilation function can be suggested: with high hereditary coefficients that remain unchanged with age, with low coefficients gamma 2 that are the same in both age groups, with increasing hereditary coefficients in aging, and with the high Ignatiev-Jensen criteria in the group of people aged 20-44 and declining ones in the group aged 45-80. The last group of ventilation variables is the largest. In the group aged 20-44 a test with oxygen inhalation increases the effect of environmental factors whereas in the group aged 45-80 it decreases this effect on the indices of the lung ventilation.
Ivanov
L A
LA
D000328:Adult; D000368:Aged; D000375:Aging / Q000235:genetics / Q000502:physiology*; D004777:Environment; D005260:Female; D005838:Genotype; D006801:Humans; D008168:Lung / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D012119:Respiration / Q000235:genetics / Q000502:physiology*; D012129:Respiratory Function Tests; D014427:Twins / Q000235:genetics*; D014430:Twins, Monozygotic / Q000235:genetics*
Sootnoshenie nasledstvennogo i sredovogo vliianiĭ na funktsiiu vneshnego dykhaniia i naee izmeneniia pri starenii po rezul'tatam bliznetsovykh issledovaniĭ.