Cerebral thrombosis in beta-thalassemia/hemoglobin E disease.
We describe two Chinese patients with beta-thalassemia/hemoglobin E disease who developed cerebral infarction due to occlusion or stenosis of their extracranial carotid arteries. The roles of platelet abnormalities and other factors in this condition are discussed.
Wong
V
V
University Department of Paediatrics, Queen Mary Hospital, Hong Kong.
Yu
Y L
YL
Liang
R H
RH
Tso
W K
WK
Li
A M
AM
Chan
T K
TK
D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging; D002339:Carotid Arteries / Q000000981:diagnostic imaging; D002533:Cerebral Angiography; D002544:Cerebral Infarction / Q000209:etiology; D002648:Child; D005260:Female; D006446:Hemoglobin E / Q000235:genetics; D006455:Hemoglobins, Abnormal / Q000235:genetics; D006579:Heterozygote; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000150:complications* / Q000000981:diagnostic imaging; D008297:Male; D013789:Thalassemia / Q000150:complications* / Q000235:genetics; D014057:Tomography, X-Ray Computed
D006455:Hemoglobins, Abnormal; D006446:Hemoglobin E