title: Vesical instillation of emepronium bromide in defunctionalized postobstructive noncompliant bladder: an alternative to intestinal augmentation surgery?
abstract: A contracted noncompliant bladder is an infrequent but severe complication of cutaneous ureterostomy. Recently, we effected a significant increase in bladder capacity by long-term, gentle hydraulic dilation with saline solution plus an anticholinergic drug (emepronium bromide). Based on this experience, we suggest a conservative approach like this before electing a patient for bladder augmentation or permanent diversion for any child with vesical contracture.
authors.affiliation: Institute of Urology, University of Padua, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Aragona
authors.forename: F
authors.initials: F
authors.lastname: di Tonno
authors.forename: T
authors.initials: T
authors.lastname: Prayer-Galetti
authors.forename: G
authors.initials: G
authors.lastname: Maio
authors.forename: E
authors.initials: E
authors.lastname: Ostardo
authors.forename: G
authors.initials: G
authors.lastname: Passerini Glazel
mesh_terms: D000283:Administration, Intravesical; D002675:Child, Preschool; D004106:Dilatation / Q000379:methods; D004629:Emepronium / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D000644:Quaternary Ammonium Compounds / Q000008:administration & dosage*; D012965:Sodium Chloride / Q000627:therapeutic use; D014519:Ureterostomy / Q000009:adverse effects; D001743:Urinary Bladder / Q000601:surgery; D001750:Urinary Bladder, Neurogenic / Q000188:drug therapy* / Q000209:etiology; D014563:Urodynamics / Q000502:physiology
chemical_list: D000644:Quaternary Ammonium Compounds; D004629:Emepronium; D012965:Sodium Chloride