title: [Neonatal screening for phenylketonuria and hypothyroidism. An optimizing system].
abstract: Screening for phenylketonuria and hypothyroidism in neonates is currently performed on blood samples collected on the 5th day of life. The efficacy of blood-sampling is evaluated subsequently. Double-sampled and non-sampled children are not always identified. We present a system which provides complete control of child, and was tested experimentally over one year on the 4,260 births in a maternity hospital. The sampling done by the maternity hospital as very thorough: only 0.47% of the children were not sampled spontaneously (ET = 1.07 10(-3)). The sampling of children transferred to pediatric units before the 5th day was a little less rigorous: 6.06% were not sampled before the telephone reminder (ET = 1.86 10(-2)). After a year our system ensured a 100% sampling after identification and telephone reminder for non sampled children, and allowed us to spot and count cases of double-sampling.
authors.affiliation: Laboratoire de santé publique, Faculté de Médecine, Marseille.
authors.forename: D
authors.initials: D
authors.lastname: Reviron
authors.forename: P
authors.initials: P
authors.lastname: Auquier
authors.forename: B
authors.initials: B
authors.lastname: Giusiano
authors.forename: N
authors.initials: N
authors.lastname: Maurin
authors.forename: R
authors.initials: R
authors.lastname: Sambuc
authors.forename: F
authors.initials: F
authors.lastname: Giraud
mesh_terms: D006751:Hospital Information Systems; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000517:prevention & control*; D007231:Infant, Newborn; D015997:Neonatal Screening / Q000379:methods*; D010661:Phenylketonurias / Q000097:blood / Q000517:prevention & control*
vernacular_title: Dépistage néonatal de la phénylcétonurie et de l'hypothyroïdie. Un système d'optimisation.