Hospital admission for xanthine toxicity.
A follow-up study of 35,909 outpatients who filled more than 220,000 prescriptions for theophylline over 9 years revealed 30 hospitalizations for xanthine toxicity. The overall estimated incidence rate of 7.8/10,000 person-years at risk indicates that in this population, hospitalization for xanthine toxicity is a relatively rare event.
Derby
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Boston Collaborative Drug Surveillance Program, Boston University Medical Center, Waltham, Massachusetts.
Jick
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Langlois
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Johnson
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Jick
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D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006760:Hospitalization; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011358:Product Surveillance, Postmarketing; D012307:Risk Factors; D013806:Theophylline / Q000506:poisoning* / Q000627:therapeutic use / Q000633:toxicity; D013997:Time Factors
D013806:Theophylline