Myoglobinuria: the importance of reaching a firm diagnosis--a patient with defective fatty acid oxidation.
A 52 year old man presented with myoglobinuria-induced acute renal failure requiring dialysis. Despite renal biopsy, the cause of the myoglobinuria was not established until he re-presented a year later with a milder episode. At this stage investigations, including a muscle biopsy, demonstrated a defect in fatty acid oxidation amenable to dietary and lifestyle advice. This report emphasizes the importance of reaching a definitive diagnosis in myoglobinuria.
Ellis
C J
CJ
Department of Medicine, Royal South Hants Hospital, Southampton, UK.
Dewhurst
A G
AG
Cooper
M
M
Brenton
D P
DP
Dathan
J R
JR
D058186:Acute Kidney Injury / Q000209:etiology; D004041:Dietary Fats / Q000008:administration & dosage; D005227:Fatty Acids / Q000378:metabolism*; D006801:Humans; D008052:Lipid Metabolism, Inborn Errors / Q000150:complications* / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009212:Myoglobinuria / Q000178:diet therapy / Q000209:etiology*; D010084:Oxidation-Reduction; D010172:Palmitoylcarnitine / Q000378:metabolism; D012206:Rhabdomyolysis / Q000209:etiology*
D004041:Dietary Fats; D005227:Fatty Acids; D010172:Palmitoylcarnitine