[Mathematical model of radioactive colloid transport in the evaluation of the functional state of the reticuloendothelial system].
The authors assess the functional potentialities of a mathematical model of transport of labeled colloids in the body. Some additions to and modifications of the model were analyzed. They made it possible to get 4 diagnostically important indices: the rate of colloid excretion from the vascular bed, the rate phagocytosis, RES volume, and the rate of RP accumulation by the liver. Besides, the authors presented the results of a computerized experiment for the determination of maintenance characteristics of a program developed for computer. The iteration algorithm for parameter identification based on a method of linearization of minimized function, was used in the program. They also formulated recommendations for a choice of arbitrary components of a calculation procedure and the use of a method of barrier functions, developed as a result of prolonged maintenance of the program.
Bondareva
I B
IB
Narkevich
B Ia
BIa
D000465:Algorithms; D003102:Colloids / Q000378:metabolism*; D006801:Humans; D008954:Models, Biological; D012157:Mononuclear Phagocyte System / Q000502:physiology*; D010587:Phagocytosis; D011851:Radioactivity; D012984:Software
D003102:Colloids
Issledovanie matematicheskoĭ modeli transporta radioaktivnogo kolloida dlia otsenki funktsional'nogo sostoianiia retikuloéndotelial'noĭ sistemy.