title: Mixed transcortical aphasia without anatomic isolation of the speech area.
abstract: We report two patients with mixed transcortical aphasia following left frontal lobe infarctions. Although there was no evidence of anatomic isolation of the speech area on computed tomograms or magnetic resonance imaging scans, single-photon emission computed tomography in one case demonstrated diminished blood flow over the left parietal convexity suggestive of "functional isolation" of the posterior perisylvian language zone.
authors.affiliation: Department of Neurology, University of Arizona, Tucson.
authors.forename: S Z
authors.initials: SZ
authors.lastname: Rapcsak
authors.forename: L B
authors.initials: LB
authors.lastname: Krupp
authors.forename: A B
authors.initials: AB
authors.lastname: Rubens
authors.forename: J
authors.initials: J
authors.lastname: Reim
mesh_terms: D000368:Aged; D001037:Aphasia / Q000209:etiology / Q000503:physiopathology*; D002544:Cerebral Infarction / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D005625:Frontal Lobe / Q000098:blood supply / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015899:Tomography, Emission-Computed, Single-Photon