[Percutaneous transfemoral arterial placement of 3 Fr. balloon infusion catheter for infusion chemotherapy of liver tumors].
A 3 Fr. single lumen balloon catheter was successfully introduced for arterial infusion chemotherapy by percutaneous transfemoral arterial insertion. This balloon catheter was used combined with 6.3 Fr. outer catheter coaxially. After placing the catheter into the target artery, the balloon catheter was ruptured by injecting 1 ml contrast medium. On the other hand the balloon was made as a leak balloon catheter by a small needle puncture before use. Some merits of this system were as follows: Transarterial infusion chemotherapy can be followed immediately after making a diagnosis by transfemoral angiography. At the time of rupturing the balloon, we can see the area that must be infused under the conventional fluoroscopy. In the case of leak balloon catheter no blood regurgitation through the catheter was occurred during the procedure because of elasticity of the rubber. In 40 patients having liver tumor we performed this method combined with continuous infusion of 5-fluorouracil for 3 to 5 weeks and also once a week intra-arterial administration of mitomycin C and adriamycin. In some patients hyperthermia therapy was also carried out for the purpose of potentiation of cellular chemosensitivity by low temperature hyperthermia. The result of this therapy was as follows: CR; 10.3%, PR; 20.7%, NC; 63.9% and PD; 5.1%. No serious complications were encountered in our series except for some minor arterial troubles caused by catheter tip.
Sawada
S
S
Department of Radiology, Tottori University School of Medicine.
Fujiwara
Y
Y
Koyama
T
T
Katsube
Y
Y
Kato
T
T
Oshima
T
T
Nakamura
H
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002404:Catheterization; D005260:Female; D005263:Femoral Artery; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000295:instrumentation*; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008297:Male; D008875:Middle Aged
D000970:Antineoplastic Agents