The glucagon-stimulated C-peptide test: an aid in classification of patients with diabetes mellitus.
Ninety-eight patients with diabetes mellitus (52 women and 46 men) underwent a glucagon stimulated C-peptide test. Treatment was instigated on the basis of classical criteria, independent of the test results, and remained unchanged during a 2-yr test period. The type of treatment and metabolic control were then related to the test results. Fasting C-peptide concentrations do not discriminate between insulin dependent and non-insulin dependent diabetes mellitus. C-peptide concentrations 10 min after intravenous injection of 1 mg of glucagon, however, correctly classified the patients. With the help of this test, the correct model of treatment for patients with diabetes mellitus can be chosen.
Vahlkamp
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Department of Clinical Chemistry, Streekziekenhuis Waterland, Purmerend.
Lütjens
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Nauta
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D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000032:analysis; D002096:C-Peptide / Q000097:blood*; D003920:Diabetes Mellitus / Q000145:classification*; D005260:Female; D005934:Glucagon; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged
D001786:Blood Glucose; D002096:C-Peptide; D005934:Glucagon; D006442:Glycated Hemoglobin