Current method for first and second trimester prenatal diagnosis: transabdominal chorionic villi sampling.
Transabdominal CVS (chorionic villi sampling) was performed in 40 patients belonging to first or second trimester of pregnancy with 97.5% success, using a double and later single needle technique with no immediate complications. Karyotyping by direct method was successful in 75% of samples thus indicating the feasibility of cytogenetic analysis using villus tissue from first and second trimesters of pregnancy. It is a safe, simple, rapid and practical method of prenatal diagnosis in first and second trimesters of pregnancy with a potentially lower risk for fetal and maternal complications.
Buckshee
K
K
Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi.
Parveen
S
S
Verma
I C
IC
D015193:Chorionic Villi Sampling / Q000379:methods*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy