title: Role of interleukin-2-receptor-positive cells and natural killer cells on rejected liver grafts of rats.
abstract: We explored the subpopulation and distribution of infiltrating leukocytes in rejected liver grafts using an orthotopic liver transplantation model of rats. We obtained the following results: (1) OX08- and recombinant-interleukin 2-receptor-positive cells were numerously increased in rejected grafts. (2) There was an abnormal distribution of R73-positive OX08-positive OX19-negative cells in the sinusoidal area of rejected grafts. These results suggest that R73-positive OX08-positive OX19-negative cells (natural killer cells or T cells?) have a role in the immunologic reaction in the sinusoidal area of rejected liver grafts of rats.
authors.affiliation: Department of Surgery II, University of Nagoya, School of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Hayashi
authors.forename: H
authors.initials: H
authors.lastname: Takagi
mesh_terms: D000818:Animals; D006084:Graft Rejection / Q000276:immunology*; D007519:Isoantigens / Q000276:immunology; D007694:Killer Cells, Natural / Q000276:immunology*; D008099:Liver / Q000473:pathology; D016031:Liver Transplantation / Q000276:immunology*; D008297:Male; D051381:Rats; D011912:Rats, Inbred ACI; D011917:Rats, Inbred Lew; D015375:Receptors, Interleukin-2 / Q000502:physiology*
chemical_list: D007519:Isoantigens; D015375:Receptors, Interleukin-2