title: Use of a vaccinia-rabies recombinant virus for the oral vaccination of foxes against rabies.
abstract: The vaccination of wild animals against rabies has been developed most extensively in Europe. Experiments have demonstrated the efficacy of a vaccinia-rabies recombinant virus administered by the oral route in foxes. The innocuity of this vaccine was tested in the target species as well as in several non-target wild and domestic species. Because of its safety and heat-stability, this recombinant virus should offer an excellent alternative to the attenuated strains of rabies virus currently used in the field. A large scale field trial was conducted in Belgium in October 1988 to assess the efficacy of this new vaccine-bait systems.
authors.affiliation: Department of Virology, Faculty of Veterinary Medicine, University of Liege, Brussels, Belgium.
authors.forename: B
authors.initials: B
authors.lastname: Brochier
authors.forename: I
authors.initials: I
authors.lastname: Thomas
authors.forename: B
authors.initials: B
authors.lastname: Bauduin
authors.forename: T
authors.initials: T
authors.lastname: Leveau
authors.forename: P P
authors.initials: PP
authors.lastname: Pastoret
authors.forename: B
authors.initials: B
authors.lastname: Languet
authors.forename: G
authors.initials: G
authors.lastname: Chappuis
authors.forename: P
authors.initials: P
authors.lastname: Desmettre
authors.forename: J
authors.initials: J
authors.lastname: Blancou
authors.forename: M
authors.initials: M
authors.lastname: Artois
mesh_terms: D000818:Animals; D002415:Cats; D005589:Foxes; D009115:Muridae / Q000276:immunology; D011818:Rabies / Q000517:prevention & control / Q000662:veterinary*; D011819:Rabies Vaccines / Q000008:administration & dosage* / Q000009:adverse effects; D011820:Rabies virus / Q000276:immunology; D013696:Temperature; D014611:Vaccination / Q000662:veterinary*; D014612:Vaccines / Q000276:immunology*; D014614:Vaccines, Synthetic / Q000276:immunology*; D014615:Vaccinia / Q000235:genetics / Q000276:immunology*; D014765:Viral Vaccines / Q000276:immunology*
chemical_list: D011819:Rabies Vaccines; D014612:Vaccines; D014614:Vaccines, Synthetic; D014765:Viral Vaccines