[The pathogenesis of generalized suppurative-septic complications in patients with eclampsia and massive blood loss of obstetrical origin].
Changes in immune status, central hemodynamics, oxygen regimen and endogenous intoxication indexes have been compared in patients with eclampsia combined with blood loss and in patients with isolated blood loss. It has been established that severe septic processes were 1.5 times and lethality was 4 times more frequent in the first group of patients than in patients with isolated blood loss. Generalized septic processes accompany marked secondary immune defects. The main reasons for the immune system damage are circulatory hypoxia and severe endogenous intoxication.
Vrublevskiĭ
O P
OP
Mazurov
N V
NV
Edeleva
N V
NV
Isaeva
N P
NP
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000917:Antibody Formation / Q000276:immunology; D001424:Bacterial Infections / Q000209:etiology* / Q000276:immunology / Q000503:physiopathology; D004461:Eclampsia / Q000150:complications* / Q000276:immunology / Q000503:physiopathology; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology; D007744:Obstetric Labor Complications / Q000276:immunology* / Q000503:physiopathology; D010100:Oxygen / Q000097:blood; D011247:Pregnancy; D011644:Puerperal Disorders / Q000150:complications* / Q000276:immunology / Q000503:physiopathology; D013997:Time Factors; D014592:Uterine Hemorrhage / Q000150:complications* / Q000276:immunology / Q000503:physiopathology
D010100:Oxygen
Patogenez generalizovannykh gnoĭno-septicheskikh oslozhneniĭ u bol'nykh s éklampsieĭ i massivnoĭ krovopotereĭ akusherskogo geneza.