title: [Results of percutaneous transluminal irradiation of biliary tract carcinoma with 192Iridium].
abstract: In 22 patients with bile duct carcinoma's intratumoral irradiation was performed through a percutaneous biliary drainage. 17 of them had been found to be inoperable at laparotomy, 5 others had recurrent carcinoma at the site of a biliodigestive anastomosis. The applied dose ranged from 60 to 80 Gy at 6 mm distance of the centre of the Iridium source. In 12/22 patients a clear reduction in the degree of tumor stenosis could be established. Regarding the survival of the patients (8.6 months) results were relatively poor, due to extensive metastases. Patients with a documented dilatation of tumor stenosis showed a low significant longer survival period (12.3 months) than those without detectable response (4.2 months).
authors.affiliation: Abteilung Diagnostische Radiologie I, Medizinische Hochschule Hannover.
authors.forename: P
authors.initials: P
authors.lastname: Hendrickx
authors.forename: G
authors.initials: G
authors.lastname: Luska
authors.forename: D
authors.initials: D
authors.lastname: Junker
authors.forename: R
authors.initials: R
authors.lastname: Grote
mesh_terms: D001661:Biliary Tract Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D001918:Brachytherapy / Q000379:methods; D002277:Carcinoma / Q000401:mortality / Q000532:radiotherapy*; D006801:Humans; D007496:Iridium Radioisotopes / Q000627:therapeutic use*; D009364:Neoplasm Recurrence, Local / Q000532:radiotherapy; D011879:Radiotherapy Dosage; D013997:Time Factors
chemical_list: D007496:Iridium Radioisotopes
vernacular_title: Ergebnisse der perkutan transluminalen Bestrahlung von Gallenwegskarzinomen mit 192Iridium.