title: [Instability of the detrusor. Treatment with oxybutynin chloride (Ditropan) in children].
abstract: We study the effect of oxybutynin chloride (Ditropan) in a random sample of 24 children with ages ranging from 5 to 14 years, diagnosed as having vesical instability from both the clinical and urodynamic standpoints. These effects were evaluated after a period of treatment that ranged from 10 to 36 months (x = 20). We obtained overall clinical improvement in 87.5%, and improvement of urodynamic alterations in 83.3% of the patients. We single out the beneficial effect of oxybutynin chloride with prolonged treatments, in instability of the detrusor, as well as its good tolerance.
authors.affiliation: Servicio de Urología, Hospital Ramón y Cajal, Universidad de Alcalá de Henares, Madrid.
authors.forename: J
authors.initials: J
authors.lastname: Vallejo Herrador
authors.forename: J M
authors.initials: JM
authors.lastname: Rodríguez Luna
authors.forename: A
authors.initials: A
authors.lastname: Fernández Fernández
authors.forename: L
authors.initials: L
authors.lastname: Perales Cabanas
authors.forename: J
authors.initials: J
authors.lastname: Romero Maroto
authors.forename: I
authors.initials: I
authors.lastname: Pérez Bustamante
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008333:Mandelic Acids / Q000627:therapeutic use*; D001750:Urinary Bladder, Neurogenic / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D008333:Mandelic Acids; C005419:oxybutynin
vernacular_title: Inestabilidad del detrusor. Tratamiento con cloruro de oxibutinina (Ditropan) en niños.