title: [Activation tests in the diagnosis of myasthenia gravis using repetitive stimulation].
abstract: 145 patients with confirmed myasthenia gravis were examined by repetitive stimulation at a frequency of 2-3 s-1. A decrement of the proximal muscles at rest was demonstrated in 116 (80%) of the patients and the deltoid muscle was most sensitive. In 29 patients without a significant decrement at rest activation test were supplemented. Prolonged maximum isometric contraction for a period of 1 minute revealed a subsequent decrement in 13 patients. The ischaemic test was positive in 5, incl. 1 where activation by isometric contraction was negative. The total number of patients, where impaired neuromuscular transmission was diagnosed by repetitive stimulation, increased to 130 (90%) when activation tests were used. The described activation tests are technically unpretentious, non-invasive and can be used in routine practice of any EMG laboratory.
authors.affiliation: Neurologická klinika KUNZ FN, Plzen.
authors.forename: Z
authors.initials: Z
authors.lastname: Ambler
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D004568:Electrodiagnosis / Q000379:methods; D004576:Electromyography; D005260:Female; D006801:Humans; D007537:Isometric Contraction; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000503:physiopathology*; D009157:Myasthenia Gravis / Q000175:diagnosis*
vernacular_title: Aktivacní testy pri diagnostice myasthenie gravis repetitivní stimulací.