title: Synthetic biological response modifiers; Part 1. Synthesis and immunomodulatory properties of some N2-(omega-(hypoxanthin-9-yl)alkoxycarbonyl)-L-arginines.
abstract: The synthesis and the main chemical and physical properties of some N2-(omega-(hypoxanthin-9-yl)alkoxycarbonyl)-L-arginines are described. The ability of the synthesized compounds to modulate the natural cytotoxic response (NK cells) in mice has also been analyzed and described.
authors.affiliation: Institute of Organic Chemistry, Faculty of Pharmacy, University of Milan.
authors.forename: R
authors.initials: R
authors.lastname: Stradi
authors.forename: E
authors.initials: E
authors.lastname: Rossi
authors.forename: L
authors.initials: L
authors.lastname: Perezzani
authors.forename: G
authors.initials: G
authors.lastname: Migliorati
authors.forename: C
authors.initials: C
authors.lastname: Riccardi
authors.forename: G
authors.initials: G
authors.lastname: Cornaglia
authors.lastname: Ferraris
mesh_terms: D000276:Adjuvants, Immunologic / Q000138:chemical synthesis* / Q000494:pharmacology; D000818:Animals; D001120:Arginine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D007042:Hypoxanthines / Q000138:chemical synthesis* / Q000494:pharmacology; D007155:Immunologic Factors / Q000138:chemical synthesis* / Q000494:pharmacology; D007694:Killer Cells, Natural / Q000187:drug effects; D051379:Mice; D008809:Mice, Inbred C3H; D014407:Tumor Cells, Cultured / Q000187:drug effects
chemical_list: D000276:Adjuvants, Immunologic; D007042:Hypoxanthines; D007155:Immunologic Factors; D001120:Arginine