title: Extravasation of nonionic radiologic contrast media: efficacy of conservative treatment.
abstract: The authors report four large-volume (greater than 20-mL) extravasations in adults and one intermediate-volume (18-mL) extravasation in an infant of iopamidol, a nonionic contrast medium, that occurred during dynamic enhanced computed tomography. The largest volume that extravasated (in two patients) was 150 mL. Although all five patients initially had swelling, erythema, and/or pain after extravasation, all recovered uneventfully. The authors suggest that emergent surgical drainage of all large-volume extravasations, a procedure that was recently recommended, is unnecessary. Large extravascular collections of nonionic contrast media can be well tolerated and are often resorbed without adverse sequelae.
authors.affiliation: Department of Radiology, Duke University Medical Center, Durham, NC 27710.
authors.forename: R H
authors.initials: RH
authors.lastname: Cohan
authors.forename: N R
authors.initials: NR
authors.lastname: Dunnick
authors.forename: R A
authors.initials: RA
authors.lastname: Leder
authors.forename: M E
authors.initials: ME
authors.lastname: Baker
mesh_terms: D000368:Aged; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000000981:diagnostic imaging / Q000628:therapy*; D005121:Extremities / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007223:Infant; D007479:Iopamidol / Q000008:administration & dosage / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D011859:Radiography
chemical_list: D007479:Iopamidol