title: Genetic studies among the Nagas and Hmars of eastern India.
abstract: A total of 148 Nagas (65 urban and 83 rural) and 81 Hmars from northeastern India were tested for 15 blood genetic markers. Both the Nagas and Hmars lacked haemoglobin variants and G6PD deficiency and had a high frequency of PGDC. This may be attributed to selective pressures operating at these loci. Genetic distance estimates using 41 alleles at 11 polymorphic loci showed appreciable heterogeneity between the urban and rural Nagas that were in line with the differences in gene frequencies. Considerable genetic admixture of the urban Nagas from the Hmar and other neighbouring populations is evident. The Nagas were found to be quite distant from the mainland Han Chinese and Malays as well as from the Bengalis and Oraons. However, they appear to be related to the Hmar and Lepcha. Evidence supporting the ethnohistoric origin of the Nagas from China or the South Seas is lacking.
authors.affiliation: Department of Paediatrics, National University of Singapore.
authors.forename: N
authors.initials: N
authors.lastname: Saha
authors.forename: J S
authors.initials: JS
authors.lastname: Tay
mesh_terms: D000483:Alleles; D044466:Asian People / Q000235:genetics*; D001789:Blood Group Antigens / Q000235:genetics; D005006:Ethnicity; D005787:Gene Frequency; D005819:Genetic Markers; D005828:Genetics, Population; D005954:Glucosephosphate Dehydrogenase / Q000235:genetics; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000235:genetics; D006454:Hemoglobins / Q000235:genetics; D006801:Humans; D007194:India; D010734:Phosphogluconate Dehydrogenase / Q000235:genetics; D012424:Rural Population; D014505:Urban Population
chemical_list: D001789:Blood Group Antigens; D005819:Genetic Markers; D006454:Hemoglobins; D010734:Phosphogluconate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase