Trigeminal airstream stimulation. Maturation-related cardiac and respiratory responses during REM sleep in human infants.
Thirty-three premature and full-term infants (PCA, 31.5 to 50 weeks) who were free from neurologic and cardiopulmonary disease at the time of testing underwent a standardized TAS test during polygraphically controlled REM sleep. The R-R interval and the TTOT were measured before and during TAS. The R-R interval and TTOT changes during TAS were compared to the preceding 60-second mean R-R interval and TTOT in each infant and expressed as a percentage of mean control values (ie, % RR and % TTOT). During TAS, there was a significant negative correlation between cardiac and respiratory responses and postconceptional age (p less than 0.001 and p less than 0.0001, respectively). Prolongation of both the R-R interval and the TTOT elicited by TAS was significantly blunted by maturation.
Ramet
J
J
Laboratory of Physiology, Hôpital Antoine Béclère, Clamart, France.
Praud
J P
JP
D'Allest
A M
AM
Dehan
M
M
Gaultier
C
C
D004562:Electrocardiography; D004569:Electroencephalography; D005260:Female; D006321:Heart / Q000502:physiology*; D006801:Humans; D007231:Infant, Newborn / Q000502:physiology*; D007234:Infant, Premature / Q000502:physiology*; D008297:Male; D008991:Monitoring, Physiologic; D010812:Physical Stimulation; D012016:Reference Values; D012119:Respiration / Q000502:physiology*; D012895:Sleep, REM / Q000502:physiology*; D013484:Supination; D014276:Trigeminal Nerve / Q000502:physiology*