Ventilation parameters and arterial blood gases as a prediction of hypoplasia in congenital diaphragmatic hernia.
Attempts to predict the degree of pulmonary hypoplasia associated with congenital diaphragmatic hernia have been made by evaluating the ventilation parameters and the arterial blood gasses of these patients. A CO2 index as a predictor of outcome, which correlates the PaCO2 with the ventilation index, was recently proposed. However, in this study the postductal PaO2 was a better predictor of survival. And the so-called "honeymoon period" was a better indicator of the efficacy of extracorporeal membrane oxygenation (ECMO) than the CO2 index. Nineteen patients were evaluated; 11 were treated with ECMO, and eight were not considered suitable for ECMO.
Johnston
P W
PW
Department of Neonatology, Huntington Memorial Hospital, Pasadena, CA.
Liberman
R
R
Gangitano
E
E
Vogt
J
J
D000403:Airway Resistance; D001784:Blood Gas Analysis; D015199:Extracorporeal Membrane Oxygenation; D006548:Hernia, Diaphragmatic / Q000097:blood / Q000503:physiopathology; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000002:abnormalities* / Q000503:physiopathology; D011184:Postoperative Period; D012123:Pulmonary Ventilation; D015656:Respiratory Mechanics