[Changes in rheological properties of blood in patients with chronic glomerulonephritis].
The study of rheological blood properties in patients with chronic glomerulonephritis (CGN) demonstrates an increase in red blood cells aggregation and blood viscosity 3-4-fold while red blood cells deformability is two times less compared to healthy subjects. These findings well correlated with plasma fibrinogen and protein/lipid ratio of plasma and red blood cells. The highest informative value is associated with middle-sized and maximum-sized red blood cells aggregates which are significally related with a clinical form of the disease and its activity. The evidence obtained in the study is indicative of profound microcirculatory abnormalities in CGN patients necessitating administration of active antiaggregate therapy.
Riabov
S I
SI
Gromov
A E
AE
Kulikova
A I
AI
Mitrofanova
O V
OV
D000293:Adolescent; D000328:Adult; D001809:Blood Viscosity / Q000502:physiology*; D002908:Chronic Disease; D004903:Erythrocyte Aggregation; D004907:Erythrocyte Deformability / Q000502:physiology*; D005260:Female; D005921:Glomerulonephritis / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged
Izmenenie reologicheskikh svoĭstv krovi u bol'nykh khronicheskim glomerulonefritom.