title: Sector pupillary dilation: an alternative technique.
abstract: Sector pupillary dilation is a method for controlled delivery of topical ophthalmic adrenergic agonists to stimulate the dilator muscle focally in patients predisposed to pharmacologically induced acute angle-closure glaucoma. Sector pupillary dilation can be achieved by applying a sterile cotton-tipped applicator moistened with 2.5% phenylephrine ophthalmic solution at the 6:00 o'clock limbus. A pilot study (N = 2) was conducted of one blue-eyed subject (M, age 38 years) and one brown-eyed subject (F, age 36 years) using drug contact times of 5 to 30 s in 5-s intervals. The horizontal and vertical pupil diameters were measured using photographs taken every 10 min for 1 h and every 20 min for the second hour. Sector pupil dilation developed with all application times. For the blue-eyed subject maximum sector dilation (delta = V-H = 1.5 mm) occurred with a 20-s contact time and peaked after 40 min. For the brown-eyed subject, the sector dilation effect was less marked and did not demonstrate a clear-cut peak time.
authors.affiliation: Walker Eye Clinic, Indiana University School of Optometry, Indianapolis.
authors.forename: L C
authors.initials: LC
authors.lastname: Locke
authors.forename: R
authors.initials: R
authors.lastname: Meetz
mesh_terms: D000328:Adult; D005127:Eye Color; D005260:Female; D006801:Humans; D007498:Iris / Q000187:drug effects*; D008297:Male; D008722:Methods; D010656:Phenylephrine / Q000008:administration & dosage / Q000494:pharmacology*; D010865:Pilot Projects; D011680:Pupil / Q000187:drug effects*
chemical_list: D010656:Phenylephrine