[The intravital pathologicoanatomical diagnosis and prognosis of chronic inflammatory processes in the lungs].
Bronchial biopsies and bronchoalveolar lavage (BAL) in 226 patients with chronic inflammatory pulmonary diseases of different genesis were studied using light and electron microscopies and radioautography. 76 patients were treated with endobronchial laser therapy. Two types of structural-functional reorganization of epithelium in large bronchi were established: atrophy and squamous metaplasia both accompanied by the decrease of metabolic activity of epitheliocytes, but differing in DNA synthesis level. The most essential index of the lung respiratory compartment state was revealed according to BAL data, i.e. quantitative and qualitative characteristics of alveolar macrophages. Correlation between metabolic activity of BAL cells and bronchial epithelial cells characterizing structural-function interaction of air-way and respiratory compartments of lungs in chronic inflammatory processes was found. After endobronchial laser therapy the processes was found. After endobronchial laser therapy the regeneratory processes in lungs were stimulated, their important property was structural-functional value of regenerating tissue.
Nepomniashchikh
G I
GI
Nepomniashchkikh
I M
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D000328:Adult; D000368:Aged; D001345:Autoradiography; D001706:Biopsy; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology / Q000378:metabolism; D001999:Bronchoscopy; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008168:Lung / Q000378:metabolism / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D011014:Pneumonia / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D011379:Prognosis; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000175:diagnosis / Q000473:pathology
Prizhiznennaia patologoanatomicheskaia diagnostika i prognoz khronicheskikh vospalitel'nykh protsessov v legkikh.