title: Concerning the decreased D-3-hydroxybutyrate dehydrogenase activity in the liver and heart of hyperthyroid rats.
abstract: Whereas in rat liver mitochondria the hyperthyroid state causes an increase both in fatty acid unsaturation and in the Ea of D-3-hydroxybutyrate dehydrogenase and a decrease in phase transition temperature, in hyperthyroid rat heart mitochondria these changes are negligible. D-3-hydroxybutyrate dehydrogenase in both the liver and the heart mitochondria of hyperthyroid rats is reduced by about 35% [12] but this reduction is not due to changes in membrane fluidity in either tissue. Hypothyroidism, on the other hand, affects BDH activity in neither heart nor liver.
authors.affiliation: Research Unit on Mitochondria and Energy Metabolism, National Research Council, Bari, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Lippolis
authors.forename: P
authors.initials: P
authors.lastname: Morini
authors.forename: A R
authors.initials: AR
authors.lastname: Conserva
authors.forename: E
authors.initials: E
authors.lastname: Casalino
authors.forename: C
authors.initials: C
authors.lastname: Landriscina
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000201:enzymology; D005227:Fatty Acids / Q000032:analysis; D006884:Hydroxybutyrate Dehydrogenase / Q000378:metabolism*; D006980:Hyperthyroidism / Q000378:metabolism*; D008297:Male; D008929:Mitochondria, Heart / Q000201:enzymology*; D008930:Mitochondria, Liver / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains; D013696:Temperature
chemical_list: D005227:Fatty Acids; D006884:Hydroxybutyrate Dehydrogenase