Increased concentrations of D-dimers in newborn infants.
The concentrations of D-dimers (the D fragments of fibrinogen) were measured in blood from 15 preterm infants, and 45 born at full term, to establish normal ranges. The adult normal range is less than 0.25 mg/l; 31 of the 60 infants (52%) had values less than 0.25 mg/l, in 16 (27%) they were 0.25-0.5, in eight (13%) 0.5-1, in three (5%) 1-2, and in two (3%) 2-4. D-dimer concentrations measured during the neonatal period should be interpreted with caution.
Hudson
I R
IR
Royal Hospital for Sick Children, Yorkhill, Glasgow.
Gibson
B E
BE
Brownlie
J
J
Holland
B M
BM
Turner
T L
TL
Webber
R G
RG
D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D006801:Humans; D007231:Infant, Newborn / Q000097:blood*; D007234:Infant, Premature / Q000097:blood; D012016:Reference Values
D005338:Fibrin Fibrinogen Degradation Products; C015214:fibrinogen D fragment