Use of bovine lung heparin to obviate anaphylactic shock caused by porcine gut heparin.
Intracardiac repair in a 7-year-old girl with tetralogy of Fallot was hampered because of an anaphylactic reaction with cardiopulmonary collapse caused by porcine gut heparin. This patient had an extremely rare case of hypersensitivity to porcine gut heparin but not to bovine lung heparin. Uneventful radical operation could be performed with the use of bovine lung heparin for systemic heparinization during cardiopulmonary bypass.
Harada
A
A
Division of Cardiac Surgery, Sakakibara Heart Institute, Tokyo, Japan.
Tatsuno
K
K
Kikuchi
T
T
Takahashi
Y
Y
Sai
S
S
Murakami
Y
Y
Takada
K
K
D000707:Anaphylaxis / Q000209:etiology / Q000517:prevention & control*; D000818:Animals; D002417:Cattle; D002648:Child; D004342:Drug Hypersensitivity / Q000209:etiology / Q000517:prevention & control*; D005260:Female; D006493:Heparin / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D007261:Infusions, Intra-Arterial; D013045:Species Specificity; D013552:Swine; D013771:Tetralogy of Fallot / Q000601:surgery*
D006493:Heparin