title: Rapid control of a chancroid outbreak: implications for Canada.
abstract: From June to November 1987 an outbreak of chancroid occurred in Winnipeg, the first in more than 10 years; 14 people (9 men, 5 women) were involved. Nine of the cases were confirmed through culture. A control strategy was implemented in November 1987 that included presumptive treatment of genital ulcer disease with single-dose antimicrobial therapy, intensive tracing of contacts and treatment of asymptomatic sexual contacts. The origin of the outbreak was not determined, and an epidemiologic link between all the patients could not be demonstrated. The isolates were found to contain the same plasmid; this suggested that a single clone of Haemophilus ducreyi was responsible for the outbreak.
authors.affiliation: Department of Medicine, University of Manitoba, Winnipeg.
authors.forename: P G
authors.initials: PG
authors.lastname: Jessamine
authors.forename: R C
authors.initials: RC
authors.lastname: Brunham
mesh_terms: D000328:Adult; D000368:Aged; D002170:Canada; D002443:Ceftriaxone / Q000627:therapeutic use; D002602:Chancroid / Q000188:drug therapy / Q000517:prevention & control* / Q000635:transmission; D004196:Disease Outbreaks / Q000517:prevention & control*; D005260:Female; D006191:Haemophilus ducreyi / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008350:Manitoba; D008875:Middle Aged; D010957:Plasmids; D011477:Sex Work; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D002443:Ceftriaxone; D015662:Trimethoprim, Sulfamethoxazole Drug Combination