Fetal cystic hygromata: insights gained from fetal blood sampling.
Twelve second-trimester fetuses with cystic hygroma underwent fetal blood sampling for rapid karyotyping, haematologic evaluation, and blood gas analysis. An abnormal karyotype was found in seven cases: monosomy X in five, trisomy 21 in one, and trisomy 13 in the other. Eight of ten fetuses undergoing blood gas analysis showed hypoxaemia, five of which were growth-retarded. Nine pregnancies were terminated. Of the remaining three, only one fetus survived the perinatal period.
Tannirandorn
Y
Y
Royal Postgraduate Medical School, Institute of Obstetrics and Gynecology, Queen Charlotte's Chelsea Hospital, London, U.K.
Nicolini
U
U
Nicolaidis
P C
PC
Fisk
N M
NM
Arulkumaran
S
S
Rodeck
C H
CH
D001784:Blood Gas Analysis; D004909:Erythrocyte Indices; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D005315:Fetal Diseases / Q000175:diagnosis*; D006801:Humans; D007621:Karyotyping; D008202:Lymphangioma / Q000175:diagnosis*; D011247:Pregnancy; D011262:Pregnancy Trimester, Second