Pseudoinvasion with high-grade dysplasia in a colonic adenoma. Distinction from adenocarcinoma.
High-grade dysplasia was found to extend to an area of pseudoinvasion in the submucosa of a colonic adenoma mimicking invasive carcinoma. The presence of both benign and cytologically malignant epithelium and residual foci of lamina propria among the submucosal glands distinguishes this entity from adenocarcinoma arising in an adenomatous polyp.
Pascal
R R
RR
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322.
Hertzler
G
G
Hunter
S
S
Goldschmid
S
S
D000230:Adenocarcinoma / Q000473:pathology*; D000236:Adenoma / Q000473:pathology*; D000368:Aged; D003110:Colonic Neoplasms / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness