[Fatal hepatitis caused by disulfiram].
A case of fatal fulminant hepatitis following treatment with disulphiram in a man aged 34 year is reported. Acute toxic hepatitis produced by disulphiram is a rare but serious side effect with a lethality about 40%. In the case reported here, immediate withdrawal of disulphiram administration on the earliest signs of hepatitis did not prevent toxic development of severe hepatic necrosis.
Knudsen
T E
TE
Silkeborg Centralsygehus, medicinsk afdeling.
Nielsen-Kudsk
J E
JE
D000328:Adult; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D004221:Disulfiram / Q000009:adverse effects*; D006801:Humans; D008297:Male
D004221:Disulfiram
Letalt forløbende hepatitis efter disulfiram.