title: [Validation of a Doppler catheter for intravascular flow measurement in vivo. A comparison with simultaneous electromagnetic flow measurement].
abstract: A new 3-French Doppler catheter has recently been developed for direct measurement of blood flow velocity within the vessel. In in-vitro studies Doppler and real flow measurements correlated strongly. To validate this method in-vivo, phasic flow measurements in the aorta ascendens of 11 narcotized Wistar rats using Doppler and an external electromagnetic flowmeters were performed. The individual stroke volume was varied over a wide range. High intraindividual correlations were found (r = 0.92-0.99). However, a considerable variation of the slope a of the regression lines was noted (a = 0.42-1.47). Thus, qualitative registration of phasic flow is possible and relative changes of flow can be determined with sufficient accuracy through intravascular Doppler measurements. Probably due to interindividual differences of the catheter position within the vessel, however, measurements of absolute flow volumes are unreliable in this setting.
authors.affiliation: Medizinische Klinik III, Physiologisches Institut II der Eberhard-Karls-Universität Tübingen.
authors.forename: W
authors.initials: W
authors.lastname: Voelker
authors.forename: M
authors.initials: M
authors.lastname: Brändle
authors.forename: K R
authors.initials: KR
authors.lastname: Karsch
authors.forename: G
authors.initials: G
authors.lastname: Kissling
mesh_terms: D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology*; D006328:Cardiac Catheterization / Q000295:instrumentation*; D002302:Cardiac Output / Q000502:physiology; D015150:Echocardiography, Doppler / Q000295:instrumentation*; D004574:Electromagnetic Fields; D055590:Electromagnetic Phenomena; D008955:Models, Cardiovascular; D051381:Rats
vernacular_title: Validisierung eines Dopplerkatheters zur intravasalen Flussmessung in vivo. Ein Vergleich zur simultanen elektromagnetischen Flussmessung.