[A case of primary anterior mediastinal choriocarcinoma].
A 25-year-old man was admitted to our hospital because of hemosputum and abnormal shadows on chest X-ray film. The chest film showed a mass shadow located in the right hilum and multiple coin lesions in bilateral lung fields. The chest CT scan showed a bulky mass sized 7 cm X 6 cm at the anterior mediastinum. This case was suspected to be choriocarcinoma because he was young, it was rapidly progressive and also because serum LDH and beta-HCG values were raised. The specimens obtained by surgical biopsy showed HCG-stain positive syncytiotrophoblasts. Cancer chemotherapy was started with CDDP and other anti-cancer drugs, but he succumbed about 3 months after admission. Autopsy findings showed no scar formation of his testes, and the primary lesion was finally diagnosed to be in the anterior mediastinum. Extra-gonadal choriocarcinoma is rare, and beta-HCG is very useful for its diagnosis and the follow-up of the clinical course.
Narushima
M
M
Department of Internal Medicine, Showa University Fujigaoka Hospital.
Katsumura
Y
Y
Ootsuka
H
H
Shimizu
S
S
Takagi
H
H
Akisawa
T
T
Tanaka
K
K
Suzuki
H
H
Noguchi
E
E
Suzuki
T
T
D000328:Adult; D002822:Choriocarcinoma / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis*