[The morphological justification for the use of collagenoplasty in progressive myopia].
A morphological study in 20 rabbits was performed in order to investigate the response of the eye tissues and the changes in the collagen spongious preparations implanted into the episcleral space. Aseptic inflammation developing in the episcleral space was local and did not have influence on the state of the retina and choroid. The collagen implants underwent lysis, resorption and were gradually replaced by the connective tissue with the development of the episcleral scar that increased the thickness of the sclera from 1.5 to 2.5-fold during 1-2 months. These results are the basis for the successful surgical correction of the high progressing myopia.
Milovanova
Z P
ZP
Svirin
A V
AV
Istranova
E V
EV
Khashem
A
A
D000818:Animals; D003094:Collagen / Q000008:administration & dosage*; D003238:Connective Tissue / Q000187:drug effects / Q000473:pathology; D004353:Drug Evaluation, Preclinical; D004343:Drug Implants; D005123:Eye / Q000187:drug effects / Q000473:pathology; D008297:Male; D009216:Myopia / Q000473:pathology* / Q000628:therapy; D011817:Rabbits; D012590:Sclera; D013997:Time Factors
D004343:Drug Implants; D003094:Collagen
Morfologicheskoe obosnovanie primeneniia kollagenoplastiki pri progressiruiushcheĭ blizorukosti.