Neuroendocrinology and limbic epilepsy: relationships to psychopathology, seizure variables, and neuropsychological function.
Correlations were sought among neuroendocrine, psychopathologic, neuropsychological, and seizure variables in 16 male patients with limbic epilepsy. Plasma prolactin and luteinizing hormone levels were directly correlated with seizure frequency. Plasma prolactin was inversely correlated with thought disorder. Post hoc findings included a strong direct correlation between total plasma testosterone levels and aggression. These relationships may help to elucidate mechanisms related to interictal symptomatology in patients with limbic epilepsy.
Leiderman
D B
DB
Department of Neurology, Stanford University School of Medicine, California.
Csernansky
J G
JG
Moses
J A
JA
D004827:Epilepsy / Q000150:complications / Q000503:physiopathology* / Q000523:psychology; D006801:Humans; D008032:Limbic System / Q000503:physiopathology*; D008297:Male; D001523:Mental Disorders / Q000209:etiology; D009422:Nervous System Diseases / Q000209:etiology; D009484:Neuropsychology; D009490:Neurosecretory Systems / Q000503:physiopathology*; D011599:Psychopathology