title: Vocal changes in patients undergoing radiation therapy for glottic carcinoma.
abstract: A prospective evaluation of vocal changes in patients receiving radiation therapy for T1 and T2 (AJC) glottic carcinoma was undertaken in January 1987. Vocal analysis was performed prior to radiotherapy and at specific intervals throughout the radiation treatment program. The voicing ratio was extrapolated from a sustained vowel phonation using the Visipitch interfaced with the IBM-PC. Preliminary observations suggested three distinct patterns of vocal behavior: 1. reduced voicing ratio with precipitous improvement within the course of treatment, 2. high initial voicing ratio with reduction secondary to radiation induced edema, with rapid improvement in the voicing component after the edema subsided, and 3. fluctuating voicing ratio during and following treatment. Enrollment of new patients and a 2-year follow-up of current patients was undertaken.
authors.affiliation: Speech and Hearing Center, Memorial Sloan-Kettering Cancer Center, New York.
authors.forename: S
authors.initials: S
authors.lastname: Miller
authors.forename: L B
authors.initials: LB
authors.lastname: Harrison
authors.forename: B
authors.initials: B
authors.lastname: Solomon
authors.forename: R B
authors.initials: RB
authors.lastname: Sessions
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000428:Alcohol Drinking; D005931:Glottis; D006801:Humans; D007822:Laryngeal Neoplasms / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012907:Smoking; D014831:Voice / Q000528:radiation effects*