title: [Obstruction of the upper urinary tract caused by a malignant retrovesicular schwannoma. Therapeutic strategy].
abstract: We present a case of malignant Schwannoma (MS) of uncommon, retroperitoneal and retrovesical localization in a 42-year-old male, which provoked bilateral ureteral obstruction as a urological manifestation. We show our therapeutic strategy by means of a schedule of systemic neoadjuvant chemotherapy with vincristine, adriamycin, cyclophosphamide, decarbacine combined with exeresis and urinary continuity reconstruction surgery. We point out that it is a low incidence but highly aggressive tumour and that treatment continues to be local radical excision, whilst chemotherapy probably continues to have little value.
authors.affiliation: Servicios de Urología, Hospital Miguel Servet, Zaragoza.
authors.forename: C
authors.initials: C
authors.lastname: González Enguita
authors.forename: C
authors.initials: C
authors.lastname: Caro Cebrián
authors.forename: M J
authors.initials: MJ
authors.lastname: Gil Sanz
authors.forename: L
authors.initials: L
authors.lastname: Rodríguez Vela
authors.forename: I
authors.initials: I
authors.lastname: Valero Palomero
authors.forename: A
authors.initials: A
authors.lastname: Roncalés Badal
authors.forename: C
authors.initials: C
authors.lastname: Rioja Sanz
authors.forename: L A
authors.initials: LA
authors.lastname: Rioja Sanz
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D008297:Male; D009442:Neurilemmoma / Q000150:complications* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery / Q000628:therapy; D011300:Preoperative Care; D014517:Ureteral Obstruction / Q000209:etiology*; D001749:Urinary Bladder Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery / Q000628:therapy; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D004317:Doxorubicin
vernacular_title: Obstrucción del tracto urinario superior causada por un Schwannoma maligno retrovesical. Estrategia terapéutica.