title: Cervical os obliteration after laser surgery in patients with amenorrhea.
abstract: Thirty-eight postmenopausal women and one with pituitary amenorrhea underwent cervical laser surgery. The cervical canal of each patient was patent 2 weeks later. Eighteen of the 30 women reevaluated 4-48 months later had total obliteration of the cervical canal. In some patients, the cervix was obliterated and flush with the vaginal vault so that it could not be identified. Five other patients had severe cervical stenosis. Factors contributing to cervical os obliteration appeared to be the depth of the cervical defect, the lack of the physical action of blood passing through the cervical canal, and the hypoestrogenic state. This outcome makes continued adequate cytologic and colposcopic surveillance of these patients impossible and leaves them at risk for developing unrecognized cervical and endometrial disease.
authors.affiliation: Department of Obstetrics and Gynecology, Queens Hospital Center Affiliation, Long Island Jewish Medical Center, Jamaica, New York.
authors.forename: M
authors.initials: M
authors.lastname: Spitzer
authors.forename: B A
authors.initials: BA
authors.lastname: Krumholz
authors.forename: V L
authors.initials: VL
authors.lastname: Seltzer
mesh_terms: D000328:Adult; D000568:Amenorrhea / Q000150:complications*; D002584:Cervix Uteri / Q000473:pathology*; D003251:Constriction, Pathologic / Q000209:etiology; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects*; D008875:Middle Aged; D011446:Prospective Studies; D002583:Uterine Cervical Neoplasms / Q000150:complications / Q000601:surgery*