Hyperpigmentation, neutrophilic alveolitis, and erythema nodosum resulting from minocycline.
Hyperpigmentation, pulmonary infiltration, and erythema nodosum occurred in a patient receiving long-term minocycline therapy. Bronchoalveolar lavage revealed both a neutrophilic and an eosinophilic alveolitis. The pulmonary and systemic symptoms promptly resolved after discontinuation of minocycline.
Bridges
A J
AJ
Department of Internal Medicine, University of Wisconsin Hospital and Clinics, Madison, WI 53792.
Graziano
F M
FM
Calhoun
W
W
Reizner
G T
GT
D000279:Administration, Cutaneous; D000328:Adult; D001992:Bronchoalveolar Lavage Fluid / Q000032:analysis; D004893:Erythema Nodosum / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D006801:Humans; D008911:Minocycline / Q000008:administration & dosage / Q000009:adverse effects*; D009504:Neutrophils; D010859:Pigmentation Disorders / Q000139:chemically induced* / Q000473:pathology; D011658:Pulmonary Fibrosis / Q000139:chemically induced* / Q000473:pathology; D013754:Tetracyclines / Q000009:adverse effects*
D013754:Tetracyclines; D008911:Minocycline