title: Treatment of panic-like attacks with a long-acting analogue of somatostatin.
abstract: Psychiatric evaluations were completed on four patients who were treated for "idiopathic flushing" with a long-acting analogue of somatostatin. All four patients had symptom profiles consistent with a diagnosis of panic disorder. All four experienced clinically significant relief from panic-like attacks while on the experimental medication. These findings suggest a possible role for somatostatin in the pathophysiology and treatment of panic disorder.
authors.affiliation: Department of Psychiatry, University of Michigan, Ann Arbor 48109-0840.
authors.forename: J L
authors.initials: JL
authors.lastname: Abelson
authors.forename: R M
authors.initials: RM
authors.lastname: Nesse
authors.forename: A
authors.initials: A
authors.lastname: Vinik
mesh_terms: D000328:Adult; D001008:Anxiety Disorders / Q000188:drug therapy*; D005239:Fear; D005260:Female; D005483:Flushing / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D015282:Octreotide / Q000627:therapeutic use*; D010200:Panic; D011569:Psychiatric Status Rating Scales; D013997:Time Factors
chemical_list: D015282:Octreotide