(+)-Alpha-viniferin, an anti-inflammatory compound from Caragana chamlagu root.
The roots of Caragana chamlagu Lamarck (Leguminosae) are used as an anti-neuralgic, anti-rheumatic, anti-arthritic, etc. in the folk medicine of Korea. An ether extract was fractionated with monitoring of the anti-inflammatory activity, and the active principle was elucidated as (+)-alpha-viniferin on the basis of spectroscopic data, including two-dimensional nuclear magnetic resonance and circular dichroism spectra.
Kitanaka
S
S
College of Pharmacy, Nihon University, Chiba, Japan.
Ikezawa
T
T
Yasukawa
K
K
Yamanouchi
S
S
Takido
M
M
Sung
H K
HK
Kim
I H
IH
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D001572:Benzofurans / Q000032:analysis / Q000494:pharmacology*; D002351:Carrageenan; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D007723:Korea; D008297:Male; D051379:Mice; D010946:Plants, Medicinal / Q000032:analysis*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D001572:Benzofurans; C064176:alpha-viniferin; D002351:Carrageenan