title: [Acid-base balance and carbohydrate metabolism after palatoplasty in children with cleft palate].
abstract: Eighteen children with cleft palate were studied to determine whether the narrowing of epipharynx following palatoplasty results in post-operative respiratory insufficiency. Arterial blood-gas levels, acid-base balance and concentrations of blood lactate, pyruvate, inorganic phosphorus and glucose were measured before and after surgery and compared with those of seventeen children with minor operations. In both groups, respiratory insufficiency was not detected but metabolic acidosis was observed immediately after surgery. The increase in blood lactate and pyruvate was greater in palatoplasty group, indicating an enhanced anaerobic metabolism in peripheral tissues, probably due to larger surgical stress and longer anesthesia. It is concluded that the narrowing of epipharynx does not cause respiratory insufficiency after palatoplasty in children.
authors.affiliation: Second Department of Oral Surgery, Faculty of Dentistry, Kyushu University, Fukuoka.
authors.forename: C
authors.initials: C
authors.lastname: Takuma
mesh_terms: D000136:Acid-Base Equilibrium / Q000502:physiology*; D050260:Carbohydrate Metabolism; D002675:Child, Preschool; D002972:Cleft Palate / Q000378:metabolism / Q000601:surgery*; D006801:Humans; D007223:Infant; D010159:Palate / Q000601:surgery*