title: Hydrogen ultrathin phase-encoded spectroscopy (HUPSPEC).
abstract: This paper describes a new clinical spectroscopy pulse program, hydrogen ultrathin phase-encoded spectroscopy. This sequence combines high spatial resolution with magnitude hydrogen spectroscopy. A linear volume is spatially frequency encoded with a conventional readout gradient and phase encoded spectrally by incrementing the timing of acquisition. The pulse sequence is implemented on a whole-body MRI scanner and supports several standard scanner options, including autoprescanning, offset of the center of field of view in the frequency-encoding direction, and oblique imaging. Some preliminary experimental experience is reported, demonstrating the possibility of observing the spectral linewidths of fat and water in marrow, and of observing the spectral linewidths of fat and water in marrow, and of observing multiline spectra. Combination of the technique with water suppression methods in a sequence called WASHUP is also discussed.
authors.affiliation: Pendergrass Diagnostic Radiology Research Laboratory, University of Pennsylvania, Philadelphia 19104.
authors.forename: J
authors.initials: J
authors.lastname: Listerud
authors.forename: R E
authors.initials: RE
authors.lastname: Lenkinski
authors.forename: L
authors.initials: L
authors.lastname: Axel
authors.forename: M
authors.initials: M
authors.lastname: Roberts
mesh_terms: D000328:Adult; D005260:Female; D005270:Femur Head / Q000033:anatomy & histology / Q000473:pathology; D005271:Femur Head Necrosis / Q000175:diagnosis; D006801:Humans; D006859:Hydrogen; D007680:Kidney Neoplasms / Q000175:diagnosis; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D013057:Spectrum Analysis / Q000379:methods
chemical_list: D006859:Hydrogen