title: Dipyridamole-thallium myocardial scanning in the preoperative assessment of patients undergoing abdominal aortic aneurysmectomy.
abstract: Dipyridamole thallium scanning (DTS) is an imaging technique with good sensitivity for coronary artery disease (CAD). The purpose of this study was to compare the haemodynamic courses and the correlation between pulmonary capillary wedge pressure (PCWP) and central venous pressure (CVP) in patients with normal DTS (Group 1: n = 12) with those whose scans demonstrated CAD (Group 2: n = 11). Haemodynamic profiles were obtained prior to anaesthesia and at several times during surgery. The haemodynamic courses in both groups were similar with significant decreases in cardiac index, stroke index, and left ventricular stroke work index during aortic cross-clamping compared with values prior to anaesthesia. There were no significant changes in PCWP and CVP throughout the study. The correlations between PCWP and CVP were significant in both groups as were the correlations between the changes in PCWP and the changes in CVP observed at the time of cross-clamping. These correlations all had large standard errors of the estimate, however, making it impossible to predict the PCWP from the CVP with precision. It is concluded that, in a limited study population, an abnormal DTS did not identify patients in whom the PCWP and CVP correlated poorly during abdominal aortic aneurysmectomy.
authors.affiliation: Department of Anaesthesiology, Faculty of Medicine, University of British Columbia, Vancouver.
authors.forename: R P
authors.initials: RP
authors.lastname: Grant
authors.forename: C
authors.initials: C
authors.lastname: Morgan
authors.forename: M S
authors.initials: MS
authors.lastname: Page
authors.forename: D N
authors.initials: DN
authors.lastname: Malm
authors.forename: V
authors.initials: V
authors.lastname: Huckel
authors.forename: L C
authors.initials: LC
authors.lastname: Jenkins
mesh_terms: D000368:Aged; D001012:Aorta, Abdominal / Q000601:surgery; D001014:Aortic Aneurysm / Q000503:physiopathology / Q000601:surgery*; D001794:Blood Pressure / Q000502:physiology; D002302:Cardiac Output / Q000502:physiology; D002315:Cardiopulmonary Bypass; D002496:Central Venous Pressure / Q000502:physiology; D003250:Constriction; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology; D004176:Dipyridamole; D005260:Female; D015637:Gated Blood-Pool Imaging; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D007430:Intraoperative Care; D008297:Male; D011300:Preoperative Care; D011669:Pulmonary Wedge Pressure / Q000502:physiology; D013794:Thallium Radioisotopes
chemical_list: D013794:Thallium Radioisotopes; D004176:Dipyridamole