Variation in virulence among oculogenital serovars of Chlamydia trachomatis in experimental genital tract infection.
Seven different oculogenital serovars (D, E, F, G, H, I, and K) of Chlamydia trachomatis were inoculated intravaginally into CF-1 mice, and subsequent infection was monitored. The duration of infection was longest with serovars D and E. This may help to explain clinical surveys which demonstrate a high (50%) prevalence of these serovars. Furthermore, a comparison of the invasiveness of strains D and H demonstrated a much higher frequency of uterine horn infection with serovar D.
Ito
J I
JI
Department of Infectious Diseases, City of Hope National Medical Center, Duarte, California 91010.
Lyons
J M
JM
Airo-Brown
L P
LP
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D002690:Chlamydia Infections / Q000382:microbiology*; D002692:Chlamydia trachomatis / Q000145:classification / Q000276:immunology / Q000472:pathogenicity*; D005260:Female; D005831:Genital Diseases, Female / Q000382:microbiology*; D051379:Mice; D012703:Serotyping; D014621:Vagina / Q000382:microbiology
D000907:Antibodies, Bacterial