title: [Relation between DNA replication and neutral Mn 2+-dependent DNAse activity in chromatin].
abstract: In cultures of primary murine fibroblasts the 10% serum stimulates the replicative synthesis of DNA inhibited by aphidicolin and araC (cytosine arabinoside). Using direct immunofluorescence analysis, it was shown that antibodies penetrate inside the cells and after 4 hours are pooled in the nuclei, where they remain for another 20 hours. The substitution of antibodies against chromatin DNAase by bovine serum albumin of normal serum gamma-globulins does not interfere with the DNA synthesis induction.
authors.forename: V G
authors.initials: VG
authors.lastname: Vinter
authors.forename: A N
authors.initials: AN
authors.lastname: Askarova
authors.forename: N L
authors.initials: NL
authors.lastname: Zotkina
authors.forename: V V
authors.initials: VV
authors.lastname: Kulikov
authors.forename: O B
authors.initials: OB
authors.lastname: Drize
authors.forename: M A
authors.initials: MA
authors.lastname: Shliankevich
mesh_terms: D000818:Animals; D000906:Antibodies / Q000276:immunology; D002478:Cells, Cultured; D002843:Chromatin / Q000201:enzymology* / Q000378:metabolism; D004261:DNA Replication; D003851:Deoxyribonucleases / Q000276:immunology / Q000378:metabolism*; D005347:Fibroblasts / Q000201:enzymology / Q000378:metabolism; D007114:Immunization; D008099:Liver / Q000201:enzymology; D008345:Manganese / Q000378:metabolism*; D051379:Mice
chemical_list: D000906:Antibodies; D002843:Chromatin; D008345:Manganese; D003851:Deoxyribonucleases
vernacular_title: Zavisimost' replikatsii DNK ot aktivnosti neĭtral'noĭ Mn 2+-zavisimoĭ DNKazy khromatina.