title: [Determination of effective renal blood flow and the rate of glomerular filtration by sequential administration of I-131 hippuran and Yb-169 DTPA].
abstract: The authors present the results of the determination of the effective renal blood flow (ERB), the effective renal plasma flow (ERP) and the rate of glomerular filtration (GRF) by sequential administration of 131I-hippuran and 169Yb-DTPK assessing the contribution of each radionuclide in blood plasma specimens with the help of a multichannel pulse analyzer. The mean values of ERB (738.4 +/- 27.3 ml/min), ERP (391 +/- 22.4 ml/min) and GRF (128.9 ml/min) were in full accord with the literature data. The difference between GRF values calculated in the presence of 131I in plasma and after its decomposition, did not exceed 5% (6.4 +/- 1.8 ml/min), and the ratio of correlation between them was 0.948, p less than 0.01. A possibility of simultaneous determination of ERB and GRF under clinical conditions was shown.
authors.forename: Iu N
authors.initials: IuN
authors.lastname: Kasatkin
authors.forename: E V
authors.initials: EV
authors.lastname: Shliakhto
authors.forename: I B
authors.initials: IB
authors.lastname: Dolgova
authors.forename: R I
authors.initials: RI
authors.lastname: Karpikov
authors.forename: A A
authors.initials: AA
authors.lastname: Pushkarev
mesh_terms: D000328:Adult; D005919:Glomerular Filtration Rate; D006626:Hippurates; D006801:Humans; D007457:Iodine Radioisotopes; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D004369:Pentetic Acid; D011868:Radioisotopes; D012079:Renal Circulation; D015018:Ytterbium
chemical_list: D006626:Hippurates; D007457:Iodine Radioisotopes; D011868:Radioisotopes; D004369:Pentetic Acid; D015018:Ytterbium
vernacular_title: Opredelenie éffektivnogo pochechnogo krovotoka i skorosti klubochkovoĭ fil'tratsii putem posledovatel'nogo vvedeniia 131 I-gippurana i 169 Yb-DTPK.