The range of albumin concentrations in the single-void first morning urine of 1090 healthy young children.
To predict microalbuminuria easily in the diabetic outpatient clinic, we determined the range of albumin concentrations in the single-void first morning urine in 1090 healthy subjects of age 6-11 by the modified turbidimetry immunoassay (TIA) method, which uses 96-well microplates and a microplate reader to perform the assay quickly and conveniently. As the correlation coefficient of albumin concentration by the TIA uncorrected for creatinine versus corrected for creatinine was r = 0.79 (P less than 0.005), the values uncorrected for creatinine were used. When the distribution of values from 1090 healthy young children was simulated by using the chi-square test (k = 1), the 95% confidence interval was 0-18 micrograms/ml.
Kodama
K
K
Diabetes Centre, Tokyo Women's Medical College, Japan.
Tomioka
M
M
Otani
T
T
Shimizu
S
S
Uchigata
Y
Y
Hirata
Y
Y
D000419:Albuminuria; D002648:Child; D003404:Creatinine / Q000652:urine; D005260:Female; D006801:Humans; D008297:Male; D009391:Nephelometry and Turbidimetry / Q000379:methods; D011863:Radioimmunoassay / Q000379:methods; D012016:Reference Values
D003404:Creatinine