[The neuraminic acid/protein quotient in amniotic fluid: indicator for fetal maturity].
The concentration of neuraminic acid and proteins was determined in amniotic fluid of 207 pregnancies during the amniocentesis, performed in the 16.-21. week of gestation, 17 prematurities and 101 deliveries in time. The neuraminic acid/protein quotient increases significantly at term. Than, its reference range is 51.3-154.8 mumol/g (2.5-97.5 percentile). The neuraminic acid/protein quotient can be an useful prenatal indicator of the fetal maturity because of its high diagnostic specificity (97%) and sensitivity (88%).
Kästner
B
B
Institut für Pathologische Biochemie, Medizinischen Akademie Magdeburg.
Schenk
H
H
Weise
W
W
Donat
H
H
D000649:Amniocentesis; D000653:Amniotic Fluid / Q000032:analysis*; D005260:Female; D005326:Fetal Proteins / Q000032:analysis*; D005328:Fetal Viability; D006801:Humans; D009438:Neuraminic Acids / Q000032:analysis*; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012016:Reference Values
D005326:Fetal Proteins; D009438:Neuraminic Acids
Der Neuraminsäure/Protein-Quotient im Fruchtwasser: Indikator für die fetale Reife.