title: Evaluation of pupil constriction and dilation from cycling measurements.
abstract: Pupil cycling was produced using an electronic circuit so that the retina was illuminated in Maxwellian view only when pupil area exceeded an adjustable area threshold, Aref. The maximum (Amax) and minimum (Amin) amplitude of the oscillations varied linearly with Aref. These observations are described by a delay-differential equation. The Aref-dependent changes in Amax, Amin were used, respectively, to quantitate dilation and constriction. A comparison of the predicted and observed period of pupil cycling suggests that the latency times for light onset and offset are the same. Measurements of Amax, Amin provide a method for determining the average pupil light response.
authors.affiliation: Department of Physiology, McGill University, Montreal, Quebec, Canada.
authors.forename: J G
authors.initials: JG
authors.lastname: Milton
authors.forename: A
authors.initials: A
authors.lastname: Longtin
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008027:Light; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D008959:Models, Neurological; D011680:Pupil / Q000502:physiology*; D012025:Reflex, Pupillary / Q000502:physiology; D013997:Time Factors