Spectral editing of tumor 13C MRS in situ.
The editing pulse sequence DEPT (D.T. Pegg, D.M. Doddrell, and M.R. Bendall, J. Chem. Phys. 77, 2745 (1982)) was modified using a scheme of various composite pulses and a 16-step phase cycling to obtain proton-decoupled natural-abundance 13C edited subspectra of solid tumors. A solenoidal probe including a Faraday shield and an orthogonal saddle decoupling coil was built for this purpose.
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MR Research Center, Division of Radiology, Cleveland Clinic Foundation, Ohio 44106.
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Majors
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D000818:Animals; D002247:Carbon Isotopes; D002460:Cell Line; D005260:Female; D005354:Fibrosarcoma / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D051379:Mice; D008809:Mice, Inbred C3H; D009368:Neoplasm Transplantation
D002247:Carbon Isotopes