title: [The efferent therapy of the critical state due to status asthmaticus].
abstract: A total of 200 patients with severe infection-induced bronchial asthma (BA) admitted to hospital with a diagnosis of status asthmaticus (SA) have been subjected to complex examination. It has been demonstrated that SA is a severe combined toxemia that leads to insensitivity of bronchial receptor apparatus to broncholytic effects and requires efferent therapy. 50 out of 130 patients with I to II and III degree SA were resistant to conventional intensive care procedures. The patients were successfully treated with urgent hemodynamic low-volume fraction extracorporeal hemosorption (EHS). EHS ensures positive hemodynamic and detoxicating effects, removing "critical" concentration of toxic ligands that block broncholytic adrenoreception. The use of efferent therapeutic techniques in SA makes it possible to reduce the mortality rate, promote the condition arrest, relieve the critical condition, reduce the doses of broncho- and spasmolytics, glucocorticoids, facilitate future drug withdrawal, and reduce the duration of the patients' stay in intensive care units.
authors.forename: R I
authors.initials: RI
authors.lastname: Novikova
authors.forename: V P
authors.initials: VP
authors.lastname: Shano
authors.forename: A N
authors.initials: AN
authors.lastname: Nesterenko
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001249:Asthma / Q000628:therapy*; D003131:Combined Modality Therapy / Q000379:methods; D003422:Critical Care / Q000379:methods*; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D012151:Resuscitation / Q000379:methods; D013224:Status Asthmaticus / Q000503:physiopathology / Q000628:therapy*
vernacular_title: Efferentnaia terapiia kriticheskogo sostoianiia, obuslovlennogo astmaticheskim statusom.