Study of chlorhexidine-tenside interactions by means of charge-transfer chromatography.
The interactions of chlorhexidine with 42 nonionic tensides were studied by means of charge-transfer reversed-phase thin-layer chromatography. The alkyl chain of chlorhexidine interacted with the alkyl chains in the hydrophobic part of the tensides, while the ethylene oxide groups of the tensides interacted with the polar guanidine groups of chlorhexidine. These two types of interaction (hydrophobic and hydrophilic) are probably not independent of each other.
Cserháti
T
T
Central Research Institute for Chemistry, Hungarian Academy of Sciences, Budapest.
Szögyi
M
M
Lelkes
L
L
D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002710:Chlorhexidine / Q000032:analysis*; D002855:Chromatography, Thin Layer; D013501:Surface-Active Agents
D013501:Surface-Active Agents; D002710:Chlorhexidine