[In vitro enzyme inhibitory and in vivo cardioprotective activities of hibiscus (Hibiscus sabdariffa L.)].
A crude hydroalcoholic extract from Hibiscus sabdariffa L. calyces showed in vitro an appreciable enzyme-inhibiting activity towards the Angiotensin I Converting Enzyme (ACE), attributable to flavones, but weak inhibiting activities towards elastase, trypsin and alpha-chymotrypsin. The angioprotective activity in vivo, also important, was due to flavones and anthocyanins.
Jonadet
M
M
C.N.R.S. U.F.R. de Pharmacie, Clermont-Ferrand.
Bastide
J
J
Bastide
P
P
Boyer
B
B
Carnat
A P
AP
Lamaison
J L
JL
D000818:Animals; D004791:Enzyme Inhibitors; D005060:Europe; D006331:Heart Diseases / Q000517:prevention & control*; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D051381:Rats
D004791:Enzyme Inhibitors; D010936:Plant Extracts
Activités inhibitrices enzymatiques in vitro et angioprotectrice in vivo d'extraits de karkadé (Hibiscus sabdariffa L.).