title: [The mechanisms of the inhibition of erythrocyte acetylcholinesterase activity by photodynamic herbicides].
abstract: A comparative study of kinetics and mechanisms of action of some photodynamic herbicides (dipyridil, phenantroline, and acepox) on mechanical resistance and acetylcholinesterase activity of erythrocytes has been carried out. Acepox had a slight damaging effect, and phenantroline was the strongest inhibitor. The data on mechanical destruction of erythrocytes correlated with tests on toxicity of obtained samples carried out on mice and infusorians. The proposed criteria may help to search for nontoxic drugs.
authors.forename: F I
authors.initials: FI
authors.lastname: Braginskaia
authors.forename: O M
authors.initials: OM
authors.lastname: Zorina
authors.forename: N R
authors.initials: NR
authors.lastname: Borodiuk
authors.forename: V G
authors.initials: VG
authors.lastname: Kartsev
mesh_terms: D015082:2,2'-Dipyridyl / Q000494:pharmacology; D000110:Acetylcholinesterase / Q000097:blood*; D002800:Cholinesterase Inhibitors; D004910:Erythrocyte Membrane / Q000187:drug effects* / Q000201:enzymology; D006461:Hemolysis / Q000502:physiology; D006540:Herbicides / Q000494:pharmacology*; D006801:Humans; D006868:Hydrolysis / Q000187:drug effects; D066298:In Vitro Techniques; D010618:Phenanthrolines / Q000494:pharmacology; D014465:Ultrasonics
chemical_list: D002800:Cholinesterase Inhibitors; D006540:Herbicides; D010618:Phenanthrolines; D015082:2,2'-Dipyridyl; D000110:Acetylcholinesterase; C025205:1,10-phenanthroline
vernacular_title: Mekhanizmy tormozheniia aktivnosti éritrotsitarnoĭ atsetilkholinésterazy nekotorymi fotodinamicheskimi gerbitsidami.