Coronary artery spasm and myocardial infarction in a patient with normal coronary arteries: temporal relationship to pseudoephedrine ingestion.
A 28 yr-old male presented with chest pain and acute ST elevation following ingestion of pseudoephedrine. The pain and electrocardiographic changes disappeared after the administration of sublingual Nitroglycerin. Myocardial enzymes did show some evidence for myocardial necrosis. A subsequent coronary arteriogram showed no occlusive lesions. Pseudoephedrine, a sympathomimetic agent, may be implicated in the initiation of coronary spasm and myocardial infarction in some patients.
Wiener
I
I
Division of Cardiology, UCLA School of Medicine.
Tilkian
A G
AG
Palazzolo
M
M
D000328:Adult; D017023:Coronary Angiography; D003329:Coronary Vasospasm / Q000139:chemically induced* / Q000000981:diagnostic imaging; D003331:Coronary Vessels / Q000187:drug effects*; D004562:Electrocardiography / Q000187:drug effects; D004809:Ephedrine / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000139:chemically induced* / Q000000981:diagnostic imaging; D012220:Rhinitis / Q000188:drug therapy*
D004809:Ephedrine