title: A method for reconstruction of large full-thickness defects of the bony thorax.
abstract: Wide resection in 12 cases of malignant or potentially malignant lesions of the chest wall resulted in full-thickness loss of skeleton and frequently of overlying soft tissues (defect greater than or equal to 15 cm in its smallest diameter or at least 90% of the sternum resected). In reconstruction of the defect, steel bars were used to replace lost ribs and a double layer of Marlex mesh for intercostal spaces. Soft-tissue coverage and primary closure were accomplished with current plastic surgical procedures and good stability of the chest wall was achieved. Protracted respiratory support was required in only one case. Postoperative pain was managed with epidural anesthesia and routine analgesics. Functionally and cosmetically satisfactory long-term results were obtained, with no infection and no need for removal of prosthetic material. The overall 5-year and 10-year actuarial survival rates were 60% and 37.5%. If lesions are radically resectable, the extent of thoracic wall resection need not be restricted because of inability to close the defects.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Sahlgren's Hospital, University of Gothenburg, Sweden.
authors.forename: S
authors.initials: S
authors.lastname: Larsson
authors.forename: N
authors.initials: N
authors.lastname: al-Khaja
authors.forename: D
authors.initials: D
authors.lastname: Roberts
mesh_terms: D000328:Adult; D000368:Aged; D001672:Biocompatible Materials; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D019736:Prostheses and Implants; D011474:Prosthesis Design; D012272:Ribs / Q000601:surgery / Q000637:transplantation; D013899:Thoracic Neoplasms / Q000534:rehabilitation / Q000601:surgery*; D013903:Thoracic Surgery / Q000379:methods*
chemical_list: D001672:Biocompatible Materials