title: Dopaminergic afferents to the mesencephalic trigeminal nucleus of the rat: a light and electron microscope immunocytochemistry study.
abstract: The localization and sources of dopaminergic projections on the primary afferent neurons in the mesencephalic trigeminal nucleus (Me5) of the rat were studied using light and electron microscopic immunocytochemical staining techniques combined with anterograde and retrograde neuroanatomical tract tracing methods. Me5 neurons were found to receive a dopaminergic input that is part of a dopaminergic fibre plexus extending over the neighbouring nucleus parabrachialis and locus coeruleus. These dopaminergic afferents originate from the substantia nigra, the ventral tegmental area and the medial hypothalamus.
authors.affiliation: Department of Neurobiology and Oral Physiology, University of Groningen, The Netherlands.
authors.forename: J C
authors.initials: JC
authors.lastname: Copray
authors.forename: R S
authors.initials: RS
authors.lastname: Liem
authors.forename: G J
authors.initials: GJ
authors.lastname: Ter Horst
authors.forename: J D
authors.initials: JD
authors.lastname: van Willigen
mesh_terms: D000818:Animals; D004298:Dopamine / Q000378:metabolism* / Q000502:physiology; D007033:Hypothalamus, Middle / Q000166:cytology / Q000378:metabolism*; D007150:Immunohistochemistry; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013378:Substantia Nigra / Q000166:cytology / Q000378:metabolism*; D013681:Tegmentum Mesencephali / Q000166:cytology / Q000378:metabolism*; D014278:Trigeminal Nuclei / Q000378:metabolism* / Q000648:ultrastructure
chemical_list: D004298:Dopamine