Total red cell Ca2+ content and rheological determinants in a group of subjects with vascular atherosclerotic disease.
We evaluated the total red cell Ca2+ content and the macro- and microrheological determinants in a group of subjects with vascular atherosclerotic disease (VAD). From the results obtained it is evident that, compared to controls, the VAD group presents an alteration of the macro- and microrheological parameters. No difference is evident for the red cell Ca2+ content in normals and in VAD subjects. No relationship is present between total red cell Ca2+ content, VBC (volume blood cells), MEA (mean erythrocyte aggregation) and red cell membrane fluidity expressed as Iex/Im ratio. In contrast to the latter, are the correlation between the red cell Ca2+ content and the degree of polarization obtained with fatty acid probes.
Caimi
G
G
Istituto di Clinica Medica e Malattie Cardiovascolari, Università di Palermo, Italy.
Lo Presti
R
R
Serra
A
A
Grifò
G
G
Romano
A
A
Catania
A
A
Sarno
A
A
D000368:Aged; D001161:Arteriosclerosis / Q000097:blood*; D002118:Calcium / Q000097:blood*; D004903:Erythrocyte Aggregation; D004911:Erythrocyte Volume; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D005374:Filtration; D005456:Fluorescent Dyes; D006801:Humans; D008297:Male; D008560:Membrane Fluidity / Q000502:physiology; D008875:Middle Aged
D005456:Fluorescent Dyes; D002118:Calcium