Non-immunological facets of poliovirus vaccines.
Failures of oral poliovirus vaccine lots in developing countries are explained by interference during their 'take' by other enteroviruses colonizing the host intestinal system. Oral poliovirus vaccines, on their part, have also exerted an interfering effect on multiplication of other enteroviruses. Apart from the intrafamilial enterovirus interference, oral poliovirus vaccine has not spared rotaviruses.
Arya
S C
SC
Centre of Logistical Research and Innovation, New Delhi, India.
D002648:Child; D003906:Developing Countries; D003967:Diarrhea / Q000517:prevention & control; D004769:Enterovirus Infections / Q000517:prevention & control; D006801:Humans; D007231:Infant, Newborn; D011055:Poliovirus Vaccine, Oral / Q000494:pharmacology*; D014762:Viral Interference
D011055:Poliovirus Vaccine, Oral