[The simultaneous synthesis of peptides and oligonucleotides on kaolinite with the participation of aminoacyladenylates].
A simultaneous synthesis of peptides (2-5 residues) and oligonucleotides (3-9 residues) has been carried out on caolinite matrix using amino acids and aminoacyladenylates as substrates. The rate of oligomer synthesis on mineral surface is higher than that in solution. The mechanism of synthesis has been described. The data has been discussed in connection with abiogenesis of two major types of biopolymers, proteins and nucleic acids.
Egofarova
R Kh
RKh
Vasil'eva
N V
NV
Moiseeva
L N
LN
Otroshchenko
V A
VA
Pavlovskaia
T E
TE
D000249:Adenosine Monophosphate / Q000031:analogs & derivatives; D000596:Amino Acids; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D066298:In Vitro Techniques; D007616:Kaolin; D009841:Oligonucleotides / Q000032:analysis / Q000138:chemical synthesis*; D010455:Peptides / Q000032:analysis / Q000138:chemical synthesis*; D013696:Temperature
D000596:Amino Acids; D009841:Oligonucleotides; D010455:Peptides; D007616:Kaolin; D000249:Adenosine Monophosphate
Odnovremennyĭ sintez peptidov i oligonukleotidov na kaolinite s uchastiem aminoatsiladenilatov.