title: Pregnancy in panhypopituitarism.
abstract: The case of a 30-year-old pregnant patient suffering from panhypopituitarism is presented. Pregnancy induced by HMG/HCG had been uneventful. Induction of labor by PGE2 vaginal tablets and by intravenous oxytocin at 42 gestational weeks failed and the patient was operated. Following the operation severe exacerbation of her diabetes insipidus occurred. Fluid balance mechanism failed and electrolyte status deteriorated rapidly. The importance of pitressin in maintenance of fluid and electrolyte balance in panhypopituitaric patients in labor and surgical trauma is stressed.
authors.affiliation: Department of Ob-Gyn B, Serlin Maternity Hospital (Hakyria), Tel Aviv Medical Center, Israel.
authors.forename: A
authors.initials: A
authors.lastname: Golan
authors.forename: L
authors.initials: L
authors.lastname: Abramov
authors.forename: G
authors.initials: G
authors.lastname: Yedwab
authors.forename: M P
authors.initials: MP
authors.lastname: David
mesh_terms: D000328:Adult; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D006854:Hydrocortisone / Q000009:adverse effects; D007018:Hypopituitarism / Q000150:complications / Q000188:drug therapy*; D007751:Labor, Induced; D011241:Prednisone / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D013974:Thyroxine / Q000627:therapeutic use; D014667:Vasopressins / Q000627:therapeutic use; D014883:Water-Electrolyte Imbalance / Q000209:etiology / Q000628:therapy
chemical_list: D014667:Vasopressins; D013974:Thyroxine; D011241:Prednisone; D006854:Hydrocortisone