title: Elevated endogenous nitrate synthesis associated with giardiasis.
abstract: Mean nitrate content in the morning urine of 117 patients with giardiasis comprises 155.3 mg/l, which exceeds about 4 fold the normal value. Maximum concentrations of 1000 mg/l were observed. Under treatment with metronidazol (Vagimid) nitrate content at first increased and then restored to normal. Endogenously synthesized nitrate with giardiasis 3-4 fold exceeds the daily nitrate intake by food and, therefore, plays an important role in total nitrate load of the patients.
authors.affiliation: Forschungsinstitut für Hygiene und Mikrobiologie Bad Elster, GDR.
authors.forename: K
authors.initials: K
authors.lastname: Wettig
authors.forename: H J
authors.initials: HJ
authors.lastname: Dobberkau
authors.forename: F
authors.initials: F
authors.lastname: Flentje
mesh_terms: D000328:Adult; D000818:Animals; D005243:Feces / Q000469:parasitology; D005260:Female; D005872:Giardia / Q000302:isolation & purification; D005873:Giardiasis / Q000188:drug therapy / Q000652:urine*; D006801:Humans; D007223:Infant; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D009573:Nitrites / Q000652:urine*; D011247:Pregnancy; D011292:Premedication
chemical_list: D009573:Nitrites; D008795:Metronidazole