title: Detecting early glaucomatous field defects with the size I stimulus and Statpac.
abstract: The influence of stimulus size and normal database on the detection of visual field defects in automated static threshold perimetry (Humphrey Field Analyzer) was investigated in 82 eyes having a diagnosis of normal, glaucoma suspect, or early glaucoma. Using a mathematically derived 'normal' database, which assumes constantly decreasing threshold sensitivities with increasing eccentricity, the size I stimulus showed significantly greater sensitivity than the size III stimulus for detecting small, shallow scotomata in the central visual field. The use of Statpac, which contains an empirically derived, age-related normal database, increased the sensitivity significantly over that of the size III stimulus (with its mathematical model), and to a degree similar to that of the size I stimulus. The results obtained with the size I stimulus were reproducible and independent of the patient's age. This study suggests a potential role for the size I stimulus in evaluating eyes having or at risk of developing early glaucomatous field loss.
authors.affiliation: Department of Ophthalmology, University of Cincinnati College of Medicine, Ohio.
authors.forename: A H
authors.initials: AH
authors.lastname: Zalta
authors.forename: J C
authors.initials: JC
authors.lastname: Burchfield
mesh_terms: D000328:Adult; D005901:Glaucoma / Q000503:physiopathology*; D006801:Humans; D008433:Mathematics; D008875:Middle Aged; D008954:Models, Biological; D012684:Sensory Thresholds / Q000502:physiology; D058609:Visual Field Tests / Q000379:methods; D014794:Visual Fields / Q000502:physiology*