title: Occurrence of the general control of amino acid biosynthesis in yeasts.
abstract: The response of three amino acid biosynthetic enzymes, threonine dehydratase, tyrosine aminotransferase and saccharopine dehydrogenase, to conditions of histidine, tryptophan or lysine limitation was investigated in 15 yeast species. The activities of all these enzymes increased about two- to fourfold as a result of action of the general control of amino acid biosynthesis in Brettanomyces anomalus, Candida maltosa, Hansenula polymorpha, Rhodosporidium toruloides, Saccharomyces cerevisiae and Yarrowia lipolytica. No evidence for the existence of the general control was found in Candida brumptii, Candida utilis, Hansenula anomala, Hansenula henricii, Kluyveromyces marxianus, Pichia guilliermondii, Saccharomycopsis capsularis, Trichosporon adeninovorans and Trigonopsis variabilis.
authors.affiliation: Sektion Biologie der Ernst-Moritz-Arndt-Universität Greifswald, WB Molekularbiologie.
authors.forename: R
authors.initials: R
authors.lastname: Bode
authors.forename: K
authors.initials: K
authors.lastname: Schüssler
authors.forename: H
authors.initials: H
authors.lastname: Schmidt
authors.forename: T
authors.initials: T
authors.lastname: Hammer
authors.forename: D
authors.initials: D
authors.lastname: Birnbaum
mesh_terms: D000596:Amino Acids / Q000096:biosynthesis*; D000640:Amitrole / Q000494:pharmacology; D014364:Tryptophan / Q000031:analogs & derivatives / Q000494:pharmacology; D015003:Yeasts / Q000378:metabolism*
chemical_list: D000596:Amino Acids; C004182:5-methyltryptophan; D014364:Tryptophan; D000640:Amitrole