title: Is there an isolated arrhythmogenic right atrial myocarditis?
abstract: Two cases with drug refractory ectopic atrial tachycardia are described. A map-guided partial resection of the right atrium (RA) was done after preoperative endocardial catheter mapping had shown well-defined areas of fractionated RA potentials. Intraoperatively, there were no aneurysmal formations present as described by other authors. Histopathologic examination of the resected tissue showed atrial myocarditis in both patients. Postoperative right ventricular myocardial biopsies revealed no inflammatory tissue. A minor elevation of antibodies against echoviruses was found in one case. Postoperative electrophysiologic studies were negative. We conclude: focal RA myocarditis without concomitant ventricular myocarditis may represent one cause of drug-resistant ectopic atrial tachycardia. Map-guided surgical intervention may cure the disease.
authors.affiliation: Division of Cardiology, Medical Clinic, University Hospital, Lausanne, Switzerland.
authors.forename: M
authors.initials: M
authors.lastname: Fromer
authors.forename: C
authors.initials: C
authors.lastname: Genton
authors.forename: J
authors.initials: J
authors.lastname: Schlaepfer
authors.forename: J J
authors.initials: JJ
authors.lastname: Goy
authors.forename: L
authors.initials: L
authors.lastname: Kappenberger
mesh_terms: D000328:Adult; D004562:Electrocardiography; D005355:Fibrosis; D006325:Heart Atria / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D009205:Myocarditis / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D009206:Myocardium / Q000473:pathology; D009336:Necrosis; D013612:Tachycardia, Ectopic Atrial / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D013617:Tachycardia, Supraventricular / Q000209:etiology*