Chronic intake of panax ginseng extract stabilizes sleep and wakefulness in food-deprived rats.
The amount of wakefulness and slow wave sleep significantly fluctuated during 48 h food deprivation and subsequent recovery periods in freely behaving male rats. In contrast, such fluctuations were significantly less prominent in age-matched male rats chronically treated with Panax ginseng extract via drinking water. It is speculated that the ginseng extract may exert a stabilizing effect on sleep-waking disturbances which possibly accounts for its outstanding health-improving activities.
Lee
S P
SP
Institute for Medical and Dental Engineering, Tokyo Medical and Dental University, Japan.
Honda
K
K
Rhee
Y H
YH
Inoué
S
S
D000818:Animals; D002940:Circadian Rhythm; D005508:Food Deprivation / Q000502:physiology*; D008297:Male; D011134:Polysaccharides / Q000008:administration & dosage*; D051381:Rats; D011919:Rats, Inbred Strains; D012890:Sleep / Q000187:drug effects*; D014851:Wakefulness / Q000187:drug effects*
D011134:Polysaccharides; C044185:panaxans