[Effect of partial pressure of solute oxygen on the intensity of respiration of cultures of antibiotic producers].
It was shown possible to use feeding of hydrogen peroxide as a method for investigating the impact of dissolved oxygen concentrations on growth and development of microorganisms. The influence of pO2 on the respiration intensity was studied in penicillin- and erythromycin-producing cultures and it was found that dependence of the respiration intensity on pO2 had the form of a curve with saturation, at pO2 equal to zero the value of the culture respiration intensity being different from zero. A mathematical model accounting for the presence in the fermentation broth of microbial agglomerates with the average size depending on the agitation conditions is proposed for describing the relationships.
Arzumanian
O G
OG
Shnaĭder
L E
LE
Tarasova
S S
SS
Biriukov
V V
VV
Mal'tsev
N I
NI
D000388:Air; D003470:Culture Media; D004917:Erythromycin / Q000096:biosynthesis*; D005285:Fermentation / Q000187:drug effects / Q000502:physiology; D066298:In Vitro Techniques; D010100:Oxygen / Q000008:administration & dosage*; D010101:Oxygen Consumption; D010406:Penicillins / Q000096:biosynthesis*; D010407:Penicillium / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D012996:Solutions; D013302:Streptomyces / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism
D003470:Culture Media; D010406:Penicillins; D012996:Solutions; D004917:Erythromycin; D010100:Oxygen
Vliianie partsial'nogo davleniia rastvorennogo kisloroda na intensivnost' dykhaniia kul'tur-produtsentov antibiotikov.