Glycoprotein expression in foetal and adult mouse cerebellum.
1. Explants of cerebellum from foetal mouse were cultured in vitro for up to 12 days. Some glycoprotein components displayed time-dependent changes in concentration in the cultured explants. 2. The specific activity of several enzymes involved in the biosynthesis or degradation of N-linked glycoproteins, increased markedly in the cerebellar explants as a function of time in culture. 3. Glycoprotein expression in foetal mouse cerebellum is compared with that in the adult tissue.
Carroll
M
M
Department of Biochemistry, London Hospital Medical College, UK.
Bird
M M
MM
D000818:Animals; D002531:Cerebellum / Q000201:enzymology / Q000378:metabolism* / Q000648:ultrastructure; D046508:Culture Techniques; D005333:Fetus / Q000378:metabolism; D006023:Glycoproteins / Q000302:isolation & purification / Q000378:metabolism*; D008565:Membrane Proteins / Q000302:isolation & purification / Q000378:metabolism; D051379:Mice; D008970:Molecular Weight; D009419:Nerve Tissue Proteins / Q000302:isolation & purification / Q000378:metabolism*; D012995:Solubility
D006023:Glycoproteins; D008565:Membrane Proteins; D009419:Nerve Tissue Proteins