title: Localization of mediastinal parathyroid adenoma by T1-201 scintiscan and SPECT.
abstract: A 64-year-old female patient was admitted to our department for fatigue, pain in the right upper abdomen, obstipation, and meteorism. The laboratory findings showed total calcium and ionized calcium elevated, phosphate close to lower limit, and parathyroid hormone increased. T1-201/Tc-99m subtraction scintiscan of the neck and upper mediastinal region did not give any evidence of isolated enhanced uptake suggesting the presence of parathyroid adenoma. After further increases in calcium and parathyroid hormone level T1-201 whole-body scan and single photon emission computed tomography of the thoracic region were performed. These revealed a circumscribed T1-201 uptake in the mediastinum immediately cranial ventral to the heart base. The postcontrast transmission computed tomography of this area confirmed the finding of the T1-201 scintigraphy with a 4 x 3 x 2 cm tumor. After sternotomy and surgical removal of the mediastinal parathyroid adenoma (chief cell adenoma), calcium and parathyroid hormone levels returned to normal values.
authors.affiliation: Abteilung Innere Medizin, Barmherzige Brüder Eggenberg Hospital, Graz.
authors.forename: P
authors.initials: P
authors.lastname: Lind
authors.forename: W
authors.initials: W
authors.lastname: Langsteger
authors.forename: P
authors.initials: P
authors.lastname: Költringer
authors.forename: B
authors.initials: B
authors.lastname: Eber
authors.forename: F
authors.initials: F
authors.lastname: Kammerhuber
authors.forename: F
authors.initials: F
authors.lastname: Smolle-Jüttner
authors.forename: O
authors.initials: O
authors.lastname: Eber
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging* / Q000601:surgery; D002118:Calcium / Q000097:blood; D002828:Choristoma / Q000000981:diagnostic imaging* / Q000601:surgery; D006801:Humans; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery; D010280:Parathyroid Glands; D010281:Parathyroid Hormone / Q000097:blood; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D010281:Parathyroid Hormone; D013794:Thallium Radioisotopes; D002118:Calcium