[Immunological reactivity during the pathogenetic treatment of experimental tuberculosis].
The authors studied the state of the T- and B-systems of immunity in guinea pigs and mice of the C57Bl6/Sto lines in the treatments of experimental tuberculosis when isoniazide and rifampicin treatment was associated with RNAse, contrical and indomethacin. It was established that this combined treatment produced a positive effect on the specific immunological reactivity. The treatment scheme using indomethacin proved most effective.
Sibirnaia
R I
RI
Snitinskaia
O S
OS
D000818:Animals; D000995:Antitubercular Agents / Q000627:therapeutic use; D004353:Drug Evaluation, Preclinical; D004359:Drug Therapy, Combination; D006168:Guinea Pigs; D007111:Immunity, Cellular / Q000187:drug effects / Q000276:immunology; D007113:Immunity, Innate / Q000187:drug effects / Q000276:immunology; D008297:Male; D051379:Mice; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000276:immunology*
D000995:Antitubercular Agents
Immunologicheskaia reaktivnost' pri patogeneticheskom lechenii tuberkuleza v éksperimente.