[The importance of neuronal plasticity for regeneration and transplantation in the CNS].
In the CA3 area of the hippocampus the pyramidal neurons were destroyed by intraventricular application of kainic acid. After transplantation of a suspension of embryonic hippocampal cells agglomerations of cells at the site of injection were observed. Some of them were in the layer of the destroyed neuronal population. These neurons formed dendritic branches and dendritic spines. As compared with control areas with a normal neuronal population, the neurons at the site of transplantation had less regular branching of dendrites and some of the branches were quite chaotic.
Pokorný
J
J
Fyziologický ústav fakulty vseobecného lékarství Univerzity Karlovy, Praha.
Trojan
S
S
D000818:Animals; D006624:Hippocampus / Q000166:cytology / Q000502:physiology*; D008297:Male; D009416:Nerve Regeneration; D009473:Neuronal Plasticity; D009474:Neurons / Q000637:transplantation*; D051381:Rats; D011919:Rats, Inbred Strains
Význam neuroplasticity pro regeneraci a transplantaci v CNS.