title: Antiplatelet components in Panax ginseng.
abstract: Panaxynol and ginsenosides Ro, Rg1, and Rg2 were found to be the main antiplatelet components in the diethyl ether and 1-butanol fractions, respectively, during the activity-guided fractionation of Panax ginseng, Panaxynol inhibited the aggregation, release reaction, and thromboxane formation in rabbit platelets while ginsenosides Ro, Rg1, and Rg2 suppressed the release reaction only.
authors.affiliation: Graduate Institute of Pharmaceutical Chemistry, China Medical College, Taichung, Taiwan.
authors.forename: S C
authors.initials: SC
authors.lastname: Kuo
authors.forename: C M
authors.initials: CM
authors.lastname: Teng
authors.forename: J C
authors.initials: JC
authors.lastname: Lee
authors.forename: F N
authors.initials: FN
authors.lastname: Ko
authors.forename: S C
authors.initials: SC
authors.lastname: Chen
authors.forename: T S
authors.initials: TS
authors.lastname: Wu
mesh_terms: D000818:Animals; D005894:Panax / Q000032:analysis*; D010946:Plants, Medicinal; D010975:Platelet Aggregation Inhibitors / Q000032:analysis*; D011817:Rabbits
chemical_list: D010975:Platelet Aggregation Inhibitors