[The possible connection of adenylic nucleotides to the rhythm of protein synthesis in hepatocytes in vitro].
Circahoral protein synthesis rhythms observed in hepatocytes in vitro differ in phase from the oscillations of intracellular amount of ATP. ATP added to culture medium interferes with the rhythms of protein synthesis and intracellular DNA content. Addition of ADP increases both the incorporation level of hepatocytes and ATP content. The data obtained has been discussed.
Iurovitskiĭ
Iu G
IuG
Nechaeva
N V
NV
Novikova
T E
TE
Fateeva
V I
VI
D000227:Adenine Nucleotides / Q000494:pharmacology*; D000244:Adenosine Diphosphate / Q000494:pharmacology; D000255:Adenosine Triphosphate / Q000494:pharmacology; D000818:Animals; D002478:Cells, Cultured / Q000187:drug effects / Q000378:metabolism; D002940:Circadian Rhythm / Q000187:drug effects / Q000502:physiology; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D014176:Protein Biosynthesis; D011506:Proteins / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains
D000227:Adenine Nucleotides; D011506:Proteins; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate
Vozmozhnaia sviaz' adenilovykh nukleotidov s ritmom sinteza belka v gepatotsitakh in vitro.