title: [Cardiogenic shock caused by 5-fluorouracil].
abstract: The authors report the observation of one patient in whom the first administration of chemotherapy with fluoro-5 uracil has induced a severe but reversible cardiogenic shock. The latter was preceded by a prolonged, constrictive thoracic pain without myocardial infarction constitution. The cardiac toxicity of fluoro-5 uracil has been well described in the form of anginal pains receding with the discontinuation of the treatment. However, the possible occurrence of arrhythmias, of collapse and even sudden deaths leads the authors to suggest the daily clinical and electrical observation of the patients treated with fluoro-5 uractil.
authors.affiliation: Service de Médecine interne, Centre Hospitalier Lyon-Sud, Pierre-Bénite.
authors.forename: C
authors.initials: C
authors.lastname: Mazet
authors.forename: A
authors.initials: A
authors.lastname: Dellinger
authors.forename: D
authors.initials: D
authors.lastname: Vital Durand
authors.forename: M
authors.initials: M
authors.lastname: Adnaoui
authors.forename: G
authors.initials: G
authors.lastname: Fournier
authors.forename: R
authors.initials: R
authors.lastname: Levrat
mesh_terms: D005472:Fluorouracil / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012770:Shock, Cardiogenic / Q000139:chemically induced* / Q000209:etiology
chemical_list: D005472:Fluorouracil
vernacular_title: Choc cardiogénique dû au 5-fluorouracile.