title: [Electrolyte disorders in cadaveric kidney donors before explantation and the functional development of the transplant in the early postoperative period].
abstract: In a group of cadaveric kidney transplantations the problem of the dependence of the functional development of the graft on the function of donor kidney before explanation and on the total time of ischaemia in the immediate postoperative period was investigated. Based on the plasma concentration of endogenous creatinine (PKr), urea (PUrea) and the total ischaemic time (GI), the early function of the graft cannot be predicted. On the contrary, the values of PKr, GI and the kidney index (NIKI = PKr x GI) allow an accurate prediction that the early function of the graft will not be sufficient. Early function of the graft is not likely to develop when PKr is higher than 160 mumol/l, total ischaemic time is longer than 30 hours and the NIKI is over 3,500. Severe alterations in the level of serum potassium (SK) occurred in 61.4% of the donors. In cases where SK was 3.0 mmol/l or less, early function of the graft did not develop in 82.3%. With high probability haemodialysis was necessary. More pronounced alterations of the level of SNa occurred in more than 60% of the donors. When SNa was 125 mmol/l or less, early function of the graft did not develop in 76%. Diuresis over 400 ml/h increased significantly the number of early nonfunctional grafts. In cases where fractional sodium excretion (FENa) was over 5%, early function of the graft did not develop. With a FENa less or equal to 1%, early function of the graft was most likely to develop.
authors.affiliation: Institut für Klinische und Experimentelle Medizin, Insitut für Weiterbildung von Arzten und Pharmazeuten, Prag/CSSR.
authors.forename: V
authors.initials: V
authors.lastname: Teplan
authors.forename: O
authors.initials: O
authors.lastname: Schück
authors.forename: H
authors.initials: H
authors.lastname: Nádvorníková
authors.forename: Z
authors.initials: Z
authors.lastname: Vránová
authors.forename: V
authors.initials: V
authors.lastname: Kocandrle
authors.forename: V
authors.initials: V
authors.lastname: Martínek
authors.forename: M
authors.initials: M
authors.lastname: Englis
mesh_terms: D004573:Electrolytes / Q000097:blood*; D006801:Humans; D007511:Ischemia / Q000503:physiopathology; D007668:Kidney / Q000098:blood supply; D016030:Kidney Transplantation; D011379:Prognosis; D014019:Tissue Donors
chemical_list: D004573:Electrolytes
vernacular_title: Elektrolytstörungen bei Leichennierenspendern vor der Entnahme und die Funktionsentwicklung des Transplantates in der frühen postoperativen Periode.