title: Phase diagrams of pseudo-binary phospholipid systems. II. Selected calorimetric studies on the influence of branching on the mixing properties of phosphatidylcholines.
abstract: The miscibility properties of branched phosphatidylcholines in mixtures of aqueous dispersions were studied by means of differential scanning calorimetry. The phase diagrams of four pseudo-binary systems from mixing type unbranched phosphatidylcholine/branched phosphatidylcholine/water (50 wt. % water) were investigated and discussed. The unbranched dipalmitoylphosphatidylcholine acts as a reference component of the mixtures. The phase diagrams of these four pseudo-binary phosphatidylcholine systems showed some connections between chain structure of the branched phosphatidylcholines and miscibility of the components. A change of the phase diagram type has been observed according to the branching and/or chain length differences of the phosphatidylcholines: complete miscibility and peritectic mixing behaviour. Generally we observed complete miscibility in the high-temperature phase (La-phase) and demixing in the low-temperature phases (gel phase). This is dependent on the branching and chain length differences of the mixing components.
authors.affiliation: Sektion Chemie der Technischen Universität Dresden, G.D.R.
authors.forename: H D
authors.initials: HD
authors.lastname: Dörfler
authors.forename: P
authors.initials: P
authors.lastname: Miethe
mesh_terms: D015060:1,2-Dipalmitoylphosphatidylcholine; D002151:Calorimetry / Q000379:methods; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D010713:Phosphatidylcholines; D010743:Phospholipids; D012015:Reference Standards; D014867:Water
chemical_list: D010713:Phosphatidylcholines; D010743:Phospholipids; D014867:Water; D015060:1,2-Dipalmitoylphosphatidylcholine