title: CSF beta-endorphins in childhood neuropsychiatric disorders.
abstract: Thirty-one children with autistic disorder, 8 with the Rett syndrome (RS), 2 with childhood disintegrative disorder and 5 with infantile spasms were compared with healthy adult controls with respect to cerebrospinal fluid (CSF) beta-endorphin levels. The autistic disorder and RS groups showed significantly lower values than the other groups. There were no age trends within the various groups. Further study of CSF beta-endorphins in these disorders and blindly examined age matched controls is warranted.
authors.affiliation: Child Neuropsychiatry Centre, University of Gothenburg, Sweden.
authors.forename: C
authors.initials: C
authors.lastname: Gillberg
authors.forename: L
authors.initials: L
authors.lastname: Terenius
authors.forename: B
authors.initials: B
authors.lastname: Hagberg
authors.forename: I
authors.initials: I
authors.lastname: Witt-Engerström
authors.forename: I
authors.initials: I
authors.lastname: Eriksson
mesh_terms: D000293:Adolescent; D001321:Autistic Disorder / Q000134:cerebrospinal fluid*; D001927:Brain Diseases / Q000134:cerebrospinal fluid* / Q000523:psychology; D002648:Child; D002675:Child, Preschool; D004723:Endorphins / Q000134:cerebrospinal fluid*; D005260:Female; D006801:Humans; D008297:Male; D015518:Rett Syndrome / Q000134:cerebrospinal fluid*
chemical_list: D004723:Endorphins