Auditory evoked potentials in vertebrobasilar transient ischemic attacks.
Brainstem auditory evoked potentials (BAEPs) are affected by stroke or migraine in the vertebrobasilar arterial system. Some studies have reported BAEP changes in vertebrobasilar transient ischemic attacks (TIAs), but others have shown no alterations. We recorded BAEPs in 35 patients with TIAs in the vertebrobasilar system who did not have a stroke, other neurologic disease or significant hearing loss. Thirty patients were recorded after resolution of symptoms, while five individuals still had some resolving signs or symptoms. TIA patients as a group had longer interpeak latencies, but I-III, III-V, and I-V latencies were not significantly longer than in controls. Wave V was significantly longer in latency and lower in amplitude in TIA patients, however. The patients whose TIAs had resolved at absolute and interpeak latencies were within normal limits, but three of five had interpeak latencies at or above three standard deviations beyond the normal mean in the still symptomatic group. One of these was later tested and found to be within normal limits. BAEPs after subsidence of symptoms may add little to the evaluation of vertebrobasilar ischemia, but further AEP analysis may show more definitive differences of diagnostic use. The occasional BAEP abnormality during the resolving transient ischemia supports the recently suggested continuum between ischemia and infarction in the vertebrobasilar territory.
Drake
M E
ME
Clinical Neurophysiology Laboratory, Ohio State University Hospitals, Columbus.
Pakalnis
A
A
Padamadan
H
H
Hietter
S A
SA
D000368:Aged; D001488:Basilar Artery / Q000503:physiopathology*; D001933:Brain Stem / Q000503:physiopathology*; D005072:Evoked Potentials, Auditory; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011930:Reaction Time; D014711:Vertebral Artery / Q000503:physiopathology*