title: Sandimmun metabolites: their potential to cause adverse reactions in the rat.
authors.affiliation: Department of Drug Safety Assessment, Sandoz, Basel, Switzerland.
authors.forename: P
authors.initials: P
authors.lastname: Donatsch
authors.forename: U
authors.initials: U
authors.lastname: Rickenbacher
authors.forename: B
authors.initials: B
authors.lastname: Ryffel
authors.forename: J F
authors.initials: JF
authors.lastname: Brouillard
mesh_terms: D000818:Animals; D003524:Cyclosporins / Q000493:pharmacokinetics / Q000633:toxicity*; D007166:Immunosuppressive Agents / Q000493:pharmacokinetics / Q000633:toxicity*; D007668:Kidney / Q000187:drug effects*; D007677:Kidney Function Tests; D007684:Kidney Tubules / Q000187:drug effects; D008099:Liver / Q000187:drug effects*; D008111:Liver Function Tests; D051381:Rats; D011918:Rats, Inbred SHR; D013329:Structure-Activity Relationship
chemical_list: D003524:Cyclosporins; D007166:Immunosuppressive Agents