title: Evaluation of complex congenital ventricular anomalies with magnetic resonance imaging.
abstract: Complex ventricular anomalies are frequently associated with abnormalities of thoracic and abdominal situs, arterioventricular connection, and venous connection. The definition of all components of these anomalies is difficult to accomplish with imaging techniques. This study compared the effectiveness of electrocardiographic (ECG) gated spin-echo magnetic resonance imaging (MRI) with cardiac angiography for the evaluation of all components of central cardiovascular anatomy in patients with the clinical diagnosis of single or common ventricle or complete atrioventricular (AV) septal (canal) defect. MRI studies and angiograms of 29 patients were evaluated independently. A sequential approach was used to define cardiac anatomy assessing nine anatomic features in each patient. MRI provided 261 observations and angiography provided 209 observations. In the mutual 209 observations, only 17 discrepancies were found. Comparison of MRI and angiography in individual cases showed that MRI was as effective as angiography in the depiction of ventricular anomalies, including determination of morphology and evaluation of the size of the ventricles, the orientation of the ventricular septum relative to the AV valves, as well as the origins and spatial relationships of the great arteries. MRI was more informative for the determination of thoracic and abdominal situs and systemic and pulmonary venoatrial connections, but was not as effective for the evaluation of semilunar valves. Thus MRI provides complete evaluation of central cardiovascular anatomy and is effective in the anatomic assessment of most components of complex ventricular anomalies.
authors.affiliation: Department of Radiology, University of California Medical Center, San Francisco 94143.
authors.forename: B A
authors.initials: BA
authors.lastname: Kersting-Sommerhoff
authors.forename: L
authors.initials: L
authors.lastname: Diethelm
authors.forename: P
authors.initials: P
authors.lastname: Stanger
authors.forename: R
authors.initials: R
authors.lastname: Dery
authors.forename: S M
authors.initials: SM
authors.lastname: Higashino
authors.forename: S S
authors.initials: SS
authors.lastname: Higgins
authors.forename: C B
authors.initials: CB
authors.lastname: Higgins
mesh_terms: D000293:Adolescent; D000328:Adult; D000792:Angiography; D002648:Child; D002675:Child, Preschool; D005260:Female; D006330:Heart Defects, Congenital / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006345:Heart Septal Defects, Ventricular / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009626:Terminology as Topic