Fabrication of a metal-cored multi-barrelled microiontophoresis assembly.
A method is described for fabrication of 7-barrelled microiontophoresis electrodes with a center barrel of platinum-coated tungsten. The electrodes require a minimum of expensive apparatus and can be fabricated in an hour or two. The electrodes have low recording impedance (typically 100 k omega and low resistance iontophoresis barrels (typically 20-50 M omega). Compared to electrodes with a micropipette recording barrel, these electrodes are practically noise-free and can pass ionotophoretic currents of up to 200 nA without an appreciable increase in recording noise.
Hellier
M
M
Department of Neurology, Prince Henry Hospital and School of Medicine, University of New South Wales, Sydney, Australia.
Boers
P
P
Lambert
G A
GA
D005898:Glass; D007478:Iontophoresis / Q000295:instrumentation*; D008839:Microelectrodes