The radiographic changes of scleroderma in the hands.
Hand radiographs from 160 patients with scleroderma were reviewed. The presence of calcinosis distal to the metacarpophalangeal joints was significantly associated with the female sex, disease duration over 10 years, digital ulceration, telangiectasia, tuft erosion and the presence of anticentromere antibodies. The presence of calcinosis proximal to the metacarpophalangeal joints was significantly associated with tuft erosions and erosions involving all joints. The lack of distal calcinosis was significantly associated with anti Scl 70 and antinucleolar antibodies. The prevalence of other radiological manifestations of scleroderma such as osteoarthritis, erosions and dorsal tuft modelling was documented. Specific radiological findings correlate with certain clinical and serological characteristics in scleroderma.
Doyle
T
T
Department of Radiology, Royal Melbourne Hospital.
Littlejohn
G
G
Miller
M
M
Barnett
A
A
D002114:Calcinosis; D005260:Female; D006229:Hand Dermatoses / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008297:Male; D015999:Multivariate Analysis; D011859:Radiography; D012594:Scleroderma, Localized / Q000000981:diagnostic imaging* / Q000473:pathology