[Results of combined therapy of irradiation and intra-arterial one-shot injection of cisplatin for head and neck cancers].
Thirty-six previously untreated cases of head and neck cancer were given a combined therapy of irradiation and intra-arterial, one-shot injection of Cisplatin. As a result, the primary lesions in 35 cases were seen to achieve a 66% complete remission (CR) and a 100% overall response (OR). The lymph metastases in twenty-one cases with positive node achieved a 62% CR and a 100% OR. Good, local control of supraglottic and hypopharyngeal cancers were found to be an advantageous factor considered from the standpoint of the "quality of life". The cumulative survival rate, using Kaplan-Meier's method, was 82% for the first year, and 62% for the second year. No severe side effects were observed.
Mariya
Y
Y
Dept. of Radiology, Aomori Prefectural Central Hospital.
Watanabe
S
S
Yokoyama
Y
Y
Takahashi
S
S
Kattou
K
K
Tarusawa
N
N
Tarusawa
K
K
Saikawa
Y
Y
Kamada
K
K
Yodono
H
H
D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000401:mortality / Q000532:radiotherapy; D002945:Cisplatin / Q000008:administration & dosage* / Q000627:therapeutic use; D003131:Combined Modality Therapy; D006258:Head and Neck Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000532:radiotherapy; D006801:Humans; D007269:Injections, Intra-Arterial; D012074:Remission Induction; D015996:Survival Rate
D002945:Cisplatin