title: Coma blisters: report and review.
abstract: Coma blisters are self-limited lesions that occur in the setting of coma of various causes, but are most commonly associated with barbiturate overdose. Examination of a skin biopsy specimen demonstrates the characteristic presence of eccrine sweat duct necrosis. Although the exact cause of coma blisters remains unknown, they are not related to underlying infections or rheumatologic disorders, and do not contraindicate the continued therapeutic use of barbiturates.
authors.affiliation: Department of Dermatology, Columbia University, College of Physicians and Surgeons, New York, New York.
authors.forename: C
authors.initials: C
authors.lastname: Dunn
authors.forename: J L
authors.initials: JL
authors.lastname: Held
authors.forename: J
authors.initials: J
authors.lastname: Spitz
authors.forename: D N
authors.initials: DN
authors.lastname: Silvers
authors.forename: M E
authors.initials: ME
authors.lastname: Grossman
authors.forename: S R
authors.initials: SR
authors.lastname: Kohn
mesh_terms: D000328:Adult; D001768:Blister / Q000139:chemically induced* / Q000473:pathology; D003128:Coma / Q000188:drug therapy*; D006801:Humans; D008297:Male; D010634:Phenobarbital / Q000009:adverse effects*
chemical_list: D010634:Phenobarbital