Olfactory bulb control of circadian activity rhythm in mice.
Ablation of mouse olfactory bulbs lengthened the circadian period of wheel-running activity by 43 min and delayed the onset of entrained activity by 108 min. A transient increase in activity during the light phase of the 12:12 h light-dark photoperiod also occurred following surgery. These disruptions suggest that olfactory systems can modulate mammalian circadian rhythms.
Possidente
B
B
Biopsychology Program, Skidmore College, Saratoga Springs, NY 12866.
Lumia
A R
AR
McGinnis
M Y
MY
Teicher
M H
MH
deLemos
E
E
Sterner
L
L
Deros
L
L
D000818:Animals; D002940:Circadian Rhythm; D008297:Male; D051379:Mice; D009043:Motor Activity / Q000502:physiology*; D009830:Olfactory Bulb / Q000502:physiology*