title: [In vitro enzyme inhibitory and in vivo cardioprotective activities of hibiscus (Hibiscus sabdariffa L.)].
abstract: A crude hydroalcoholic extract from Hibiscus sabdariffa L. calyces showed in vitro an appreciable enzyme-inhibiting activity towards the Angiotensin I Converting Enzyme (ACE), attributable to flavones, but weak inhibiting activities towards elastase, trypsin and alpha-chymotrypsin. The angioprotective activity in vivo, also important, was due to flavones and anthocyanins.
authors.affiliation: C.N.R.S. U.F.R. de Pharmacie, Clermont-Ferrand.
authors.forename: M
authors.initials: M
authors.lastname: Jonadet
authors.forename: J
authors.initials: J
authors.lastname: Bastide
authors.forename: P
authors.initials: P
authors.lastname: Bastide
authors.forename: B
authors.initials: B
authors.lastname: Boyer
authors.forename: A P
authors.initials: AP
authors.lastname: Carnat
authors.forename: J L
authors.initials: JL
authors.lastname: Lamaison
mesh_terms: D000818:Animals; D004791:Enzyme Inhibitors; D005060:Europe; D006331:Heart Diseases / Q000517:prevention & control*; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D051381:Rats
chemical_list: D004791:Enzyme Inhibitors; D010936:Plant Extracts
vernacular_title: Activités inhibitrices enzymatiques in vitro et angioprotectrice in vivo d'extraits de karkadé (Hibiscus sabdariffa L.).