[The effect of different regimens of artificial ventilation on the pulmonary microcirculation during the development of experimental edema].
Acute experiments were conducted on male cats with a closed chest by the biomicroscopic method to study the effect of artificial ventilation (AV) of increased frequency and volume on the diameter and length of the pulmonary microvessels and the character of blood flow in them during the development of pulmonary edema induced by intravenous infusion of a fatty acid mixture. It is shown that AV of increased frequency inhibits the reduction of the length of the functioning narrow capillaries and dilatation of the wide capillaries of the lungs as compared to the initial ventilation parameters and prevents a change in the directions of the blood flow in the pulmonary arterioles after exposure to the edematogenic effect. The diameter of the arterioles and venules reduces and that of the wide capillaries increases at the beginning of edema more in AV of increased volume than in ventilation of the initial parameters. It is assumed that AV of increased frequency is more effective than ventilation of increased volume in preventing pulmonary microcirculatory disorders in edema of the lungs.
Tkachenko
S B
SB
Kulik
A M
AM
D000818:Animals; D002415:Cats; D005069:Evaluation Studies as Topic; D008168:Lung / Q000098:blood supply*; D008297:Male; D008833:Microcirculation / Q000503:physiopathology; D000069463:Olive Oil; D010938:Plant Oils; D011654:Pulmonary Edema / Q000139:chemically induced / Q000503:physiopathology / Q000517:prevention & control*; D012121:Respiration, Artificial / Q000379:methods*; D013997:Time Factors
D000069463:Olive Oil; D010938:Plant Oils
Vliianie razlichnykh rezhimov iskusstvennoĭ ventiliatsii na mikrotsirkuliatsiiu legkikh pri razvitii ikh éksperimental'nogo oteka.