Goat-mouse hybridomas secreting goat immunoglobulins.
Monoclonal antibodies specific for an allotypic marker of goat IgG2 were used to select goat-mouse hybrid cells secreting goat IgG2. Four of these hybrid cell clones continued to synthesize goat IgG2 (5-15 micrograms/ml) for over eight months. They will be used to study goat IgG gene regulation.
Capparelli
R
R
Department of Animal Production, University of Naples, Portici (NA), Italy.
Del Sorbo
G
G
Iannelli
D
D
D000818:Animals; D002459:Cell Fusion; D002460:Cell Line; D005260:Female; D006041:Goats / Q000276:immunology*; D006825:Hybridomas / Q000276:immunology*; D007074:Immunoglobulin G / Q000378:metabolism*; D008214:Lymphocytes; D051379:Mice; D009101:Multiple Myeloma
D007074:Immunoglobulin G