Therapy of depressions in post-stroke patients.
In a study of 90 patients with post-stroke depression the Hamilton Depression Scale was used together with a clinical psychopathological study. One group of patients was treated with amitriptyline, another with minor tranquilizers (seduxen), and the third (controls) received neither antidepressants, nor tranquilizers. Only treatment in the first group was effective, i.e. depressions were reduced after therapy with amitriptyline So amitriptyline was demonstrated to be the most effective drug of choice in the treatment of non-psychotic post-stroke depressions.
Balunov
O A
OA
Department for Rehabilitation of Neurological Patients, V.M. Bekhterev Psychoneurological Research Institute, Leningrad, USSR.
Sadov
O G
OG
Alemasova AYu
D000328:Adult; D000368:Aged; D000639:Amitriptyline / Q000627:therapeutic use*; D002561:Cerebrovascular Disorders / Q000150:complications* / Q000523:psychology; D003866:Depressive Disorder / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D000639:Amitriptyline