title: A simple and accurate grading system for orthoiodohippurate renal scans in the assessment of post-transplant renal function.
abstract: Orthoiodohippurate renal scanning has proved to be a reliable, noninvasive method for the evaluation and followup of renal allograft function. However, a standardized system for grading renal function with this test is not available. We propose a simple grading system to distinguish the different functional phases of hippurate scanning in renal transplant recipients. This grading system was studied in 138 patients who were evaluated 1 week after renal transplantation. There was a significant correlation between the isotope renographic functional grade and clinical correlates of allograft function such as the serum creatinine level (p = 0.0001), blood urea nitrogen level (p = 0.0001), urine output (p = 0.005) and need for hemodialysis (p = 0.007). We recommend this grading system as a simple and accurate method to interpret orthoiodohippurate renal scans in the evaluation and followup of renal allograft recipients.
authors.affiliation: Department of Urology, Cleveland Clinic Foundation, Ohio 44195.
authors.forename: S K
authors.initials: SK
authors.lastname: Zaki
authors.forename: P N
authors.initials: PN
authors.lastname: Bretan
authors.forename: R T
authors.initials: RT
authors.lastname: Go
authors.forename: P K
authors.initials: PK
authors.lastname: Rehm
authors.forename: S B
authors.initials: SB
authors.lastname: Streem
authors.forename: A C
authors.initials: AC
authors.lastname: Novick
mesh_terms: D000328:Adult; D005500:Follow-Up Studies; D006801:Humans; D007457:Iodine Radioisotopes; D007465:Iodohippuric Acid; D007677:Kidney Function Tests; D016030:Kidney Transplantation / Q000502:physiology*; D011866:Radioisotope Renography / Q000379:methods*
chemical_list: D007457:Iodine Radioisotopes; D007465:Iodohippuric Acid