[Validity of the use of penbutolol in essential arterial hypertension].
Thirty patients suffering from WHO I-II class slight-moderate essential arterial hypertension were treated with a beta-blocker (Penbutolol) alone and once a day to assess its antihypertensive effectiveness and its affect on heart frequency, lipid metabolism and kidney function. The drug proved highly effective in reducing P.A.S. and P.A.D. values and no negative influence was documented on lipid metabolism, kidney function or heart frequency.
Pepe
S
S
Cattedra di Fisiopatologia Medica, Università degli Studi di Palermo.
Scalici
G
G
D'Angelo
A
A
Curiale
B
B
Corrao
S
S
Agnello
C
C
D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D003971:Diastole; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010394:Penbutolol / Q000627:therapeutic use*; D011412:Propanolamines / Q000627:therapeutic use*; D013599:Systole
D011412:Propanolamines; D010394:Penbutolol
Validità dell'uso del penbutololo nell'ipertensione arteriosa essenziale.