title: Epidemiology of invasive Haemophilus influenzae type b infections in Bedouins and Jews in southern Israel.
abstract: We report the epidemiology of invasive Haemophilus influenzae type b disease requiring hospital intervention in Southern Israel, an area that contains two ethnic populations, Bedouins and Jews. The study is based on 107 blood or cerebrospinal fluid culture-positive cases during the years 1984 to 1988. The annual incidence rate among children younger than 5 years of age was 51/100,000 (48/100,000 for Jews and 58/100,000 for Bedouins). Thirty-nine percent of patients had meningitis, 32% had pneumonia and 31% had otitis media. Epiglottitis was present in only one case (less than 1%). The median age was 8 months. Twenty-six percent of the cases were 6 months old or younger, 75% were 1 year old or younger and 87% were 18 months old or younger. Ninety-five percent of all meningitis cases occurred during the first 18 months of life. A projected number of 2938 hospitalization days and 9.8 deaths/year for a population in which 100,000 births occur yearly was calculated. The major impact of invasive H. influenzae type b infections and the very young age involved justify initiation of H. influenzae vaccine studies in our region.
authors.affiliation: Pediatric Infections Diseases Unit, Soroka University Medical Center, Beer-Sheva, Israel.
authors.forename: I
authors.initials: I
authors.lastname: Halfon-Yaniv
authors.forename: R
authors.initials: R
authors.lastname: Dagan
mesh_terms: D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005006:Ethnicity; D005260:Female; D006192:Haemophilus Infections / Q000453:epidemiology* / Q000208:ethnology; D006193:Haemophilus influenzae; D006801:Humans; D015994:Incidence; D007223:Infant; D007557:Israel / Q000453:epidemiology; D007585:Jews; D008297:Male; D008583:Meningitis, Haemophilus / Q000453:epidemiology / Q000208:ethnology; D012621:Seasons