[Loco-regional transcatheter thrombolysis].
Eight cases of recent arterial thrombosis (average time of symptoms: 11 days) are considered: 2 popliteal and 6 prosthetic thromboses (2 aorto-bifemoral and 4 femoropopliteal by-passes). After percutaneous catheterization, with catheter tip either in contact with or inside the thrombus, urokinase was locally injected (200,000 UI bolus, and 75,000 UI with slow infusion for 24 +/- 72 hours); general heparin treatment was also administered. PTA was employed in 2 cases (1 surgical anastomosis and 1 popliteal thrombosis). Arterial recanalization was always obtained within 72 hours in 2 aorto-bifemoral and in 1/4 femoropopliteal by-passes. Patency was also obtained in the 2 popliteal thrombosis.
Camerini
E
E
Istituto di Radiologia, Università, Pisa.
Trippi
D
D
Vignali
C
C
Susini
C
C
Orsitto
E
E
D002406:Catheterization, Peripheral / Q000379:methods; D004359:Drug Therapy, Combination; D006083:Graft Occlusion, Vascular / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D011150:Popliteal Artery / Q000000981:diagnostic imaging; D015641:Radiography, Interventional / Q000379:methods*; D015912:Thrombolytic Therapy / Q000379:methods*; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage
D006493:Heparin; D014568:Urokinase-Type Plasminogen Activator
Trombolisi loco-regionale transcatetere.