[Stabilizing selection and linkage disequilibrium].
An approach to the investigation of the evolution of quantitative traits on the basis of analysis of two-locus marginal systems dynamics has been developed. It has been shown that under stabilizing selection the "quasi-stationary" state is quickly reached and maintained continuously. The "quasi-stationary" state is characterized by small changes in allele frequencies and by linkage disequilibrium that significantly decreases genotypic variance. Equations defining the role of linkage disequilibrium in the stationary state of mutation-selection balance are derived.
Zhivotovskiĭ
L A
LA
Gavrilets
S Iu
SIu
D000483:Alleles; D008040:Genetic Linkage; D008957:Models, Genetic; D015233:Models, Statistical; D009154:Mutation; D012641:Selection, Genetic
Stabiliziruiushchiĭ otbor i neravnovesie po stsepleniiu.