title: [Endoscopic laser recanalization in the chemo- and radiotherapy of stenosing cancer of the esophagus].
abstract: The authors analyze the results of endoscopic laser recanalization in 11 patients with stenosing esophageal carcinoma, whose mean age is 61 years. The tumor was located in the upper thoracic portion of the esophagus in 3 patients, in the middle thoracic portion in 6, and in the lower thoracic portion in 2 patients. The diagnosis of carcinoma was morphologically verified. The length of the esophagus involvement was estimated by x-ray data and varied from 5 to 12 cm and longer. Endophytic form predominated--it was diagnosed in 5 patients. The technique of endoscopic laser recanalization by means of Raduga-1 unit with neodymium alumo-yttrium garnet laser as the source of irradiation is described. The method was specified with consideration for the type of tumor growth. The patients were kept on parenteral nutrition during the treatment session. Three-five days after endoscopic laser destruction long-distance open-field gamma-beam therapy was administered to 10 patients and polychemotherapy to 9 of these. After laser destruction dilatation of the stenosed portion of the esophagus from 0.2-0.6 to 1.0-2.0 cm was recorded in 10 patients. Complete regression of the tumor resultant from laser destruction and chemoradiotherapy was achieved in 5 patients, partial regression in the rest 5. The patients were followed up for 5-12 months. No recurrences were recorded in patients with complete regression of the tumor; the process progressed in 3 cases with partial regression. Studies on improvement of recanalization technique, specification of indications for and contraindications against this treatment modality are in progress.
authors.forename: Iu P
authors.initials: IuP
authors.lastname: Kuvshinov
authors.forename: B K
authors.initials: BK
authors.lastname: Poddubnyĭ
authors.forename: V M
authors.initials: VM
authors.lastname: Aliev
authors.forename: N F
authors.initials: NF
authors.lastname: Vasygova
authors.forename: O N
authors.initials: ON
authors.lastname: Efimov
authors.forename: Kh B
authors.initials: KhB
authors.lastname: Khydyrov
authors.forename: V A
authors.initials: VA
authors.lastname: Saliuk
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D004317:Doxorubicin / Q000008:administration & dosage / Q000627:therapeutic use*; D004938:Esophageal Neoplasms / Q000150:complications / Q000601:surgery*; D004940:Esophageal Stenosis / Q000209:etiology / Q000601:surgery*; D004945:Esophagoscopy; D005472:Fluorouracil / Q000008:administration & dosage*; D006801:Humans; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011867:Radioisotope Teletherapy
chemical_list: D004317:Doxorubicin; D005472:Fluorouracil
vernacular_title: Endoskopicheskaia lazernaia rekanalizatsiia v khimioluchevom lechenii stenoziruiushchego raka pishchevoda.