title: [Clinical use of ceftriaxone in short-term prophylaxis in general surgery. A case load contribution].
abstract: The results obtained after short-term surgical prophylaxis with ceftriaxone in 443 patients of whom 361 operated of choice are reported. In all, only 3 failures were encountered. The drug also proved to be well tolerated and there were no noteworthy side-effects in the treated patients. The effectiveness of prophylactic treatment is attributed to the long half-life of the molecule (about 8 hours) guaranteeing efficient antibacterial cover with just one administration for the whole period that is critical for surgical infections, during and after operation.
authors.affiliation: Ospedale S. Giacomo-Novi Ligure, Divisione di Chirurgia Generale.
authors.forename: G
authors.initials: G
authors.lastname: Brigli
authors.forename: S
authors.initials: S
authors.lastname: Sommariva
authors.forename: F E
authors.initials: FE
authors.lastname: Doria
authors.forename: F L
authors.initials: FL
authors.lastname: Doria
authors.forename: Z
authors.initials: Z
authors.lastname: Kotitsa
authors.forename: R M
authors.initials: RM
authors.lastname: Lo Casto
mesh_terms: D001424:Bacterial Infections / Q000517:prevention & control; D002443:Ceftriaxone / Q000627:therapeutic use*; D006801:Humans; D011292:Premedication; D013997:Time Factors
chemical_list: D002443:Ceftriaxone
vernacular_title: Impiego clinico del ceftriaxone in corso di profilassi "short-term" in chirurgia generale. Contributo casistico.