title: Gastrointestinal lymphoma. A case for primary surgical resection.
abstract: The cases of 42 consecutive patients with primary gastrointestinal lymphoma were reviewed to compare the risks and outcomes of different primary treatment modalities. Among patients with localized disease (stages I and II), 12 underwent complete tumor resection and 6 underwent radiation therapy; 5-year survival was 82% and 50%, respectively. Among patients with disseminated disease (stages III and IV), 6 underwent resection of the primary tumor followed by chemotherapy and 18 were treated with radiation and chemotherapy; 5-year survival was 81% and 6%, respectively. Five patients who did not undergo surgical resection before radiation therapy or chemotherapy developed severe life-threatening complications from their primary tumor. Surgical resection before the administration of other therapy should be performed when the patient is considered to be a surgical candidate and resection of the primary tumor is deemed feasible.
authors.affiliation: Department of Surgery, Northwestern University Medical School, Chicago, IL 60611.
authors.forename: M S
authors.initials: MS
authors.lastname: Talamonti
authors.forename: L G
authors.initials: LG
authors.lastname: Dawes
authors.forename: R J
authors.initials: RJ
authors.lastname: Joehl
authors.forename: D L
authors.initials: DL
authors.lastname: Nahrwold
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D005770:Gastrointestinal Neoplasms / Q000150:complications / Q000401:mortality / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology; D008223:Lymphoma / Q000150:complications / Q000401:mortality / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D011832:Radiation Injuries; D012189:Retrospective Studies; D015996:Survival Rate