title: [Structural basis of the spleen in rats].
abstract: The basic function of the spleen in the rat, similarly as in man, is to cleanse the blood of damaged old particles of the body itself, but also of foreign particles. To fulfill this function, the spleen is equipped with the white and red pulp with a specific structure of blood circulation. In an open system of circulation, blood from the arterial terminals opens into the cords of the red pulp, where it is adequately processed. From the cords the blood gets through the walls of sinuses, acting as the last filtration barrier, into the lumen of sinuses and then into the venous circulation. Unlike the human spleen, this organ in the rat has a marked marginal sinus and channel systems bridging the marginal zone. The channels mediate the circulation of lymphocytes between the red white pulp.
authors.affiliation: Oddelenia histochémie a ultrastruktúrnej patológie Centra klinických oddelení VULB v Bratislave.
authors.forename: J
authors.initials: J
authors.lastname: Jakubovský
authors.forename: M
authors.initials: M
authors.lastname: Brozman
authors.forename: M
authors.initials: M
authors.lastname: Ruzicková
authors.forename: E
authors.initials: E
authors.lastname: Surmíková
authors.forename: I
authors.initials: I
authors.lastname: Belko
authors.forename: J
authors.initials: J
authors.lastname: Líska
authors.forename: S
authors.initials: S
authors.lastname: Polák
authors.forename: I
authors.initials: I
authors.lastname: Sadlonová
authors.forename: M
authors.initials: M
authors.lastname: Belosovic
mesh_terms: D000818:Animals; D005260:Female; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000098:blood supply / Q000502:physiology / Q000648:ultrastructure*
vernacular_title: Struktúrne základy funkcie sleziny potkana.