Ion mobility detection of polydimethylsilicone oligomers following supercritical fluid chromatographic separation.
A mixture of polydimethylsilicones (Dow Corning 200), average molecular weight 2000 a.m.u., was separated by simultaneous density and temperature-programmed supercritical fluid chromatography and detected by ion mobility detection. Ion mobility spectra were captured by Fourier transform ion mobility spectrometry. Using information from these spectra it was possible to selectively detect a single compound in the complex mixture. A detector temperature investigation demonstrated that, for the efficient transfer of high-molecular-weight compounds from the column to the detector, the interface to the detector must be heated. Using a 50 microns I.D. column, a Guthrie-type restrictor and a detection temperature of 250 degrees C, as many as 70 oligomers were separated and detected.
Morrissey
M A
MA
Department of Chemistry, Washington State University, Pullman 99164-4630.
Siems
W F
WF
Hill
H H
HH
D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004129:Dimethylpolysiloxanes / Q000302:isolation & purification*; D007477:Ions; D012828:Silicones / Q000302:isolation & purification*; D013057:Spectrum Analysis
D004129:Dimethylpolysiloxanes; D007477:Ions; D012828:Silicones