[Changes in the spongiosa density in the femoral head of rabbits in atherosclerosis].
Modulations of spongiosa density in the femoral head of rabbits by atherosclerosis. In a long-term study 31 rabbits (+5 control animals) were fed about 20 weeks on a diet rich in cholesterol. An important observation in this study was, that spongiosa density in the femoral head decreases after cholesterol rich diet in contrast to the control group. This effect could be modulated by the Trapidil AR 12463 content (50 mg/die) of the diet, but not by the high density lipoprotein application. Serum cholesterol levels and induced atherosclerosis were determined. Correlations between spongiosa density and atherosclerosis were discussed.
Bartels
T
T
Klinik und Poliklinik für Orthopädie, Bereichs Medizin der Martin-Luther-Universität Halle-Wittenberg.
Beitz
J
J
Hein
W
W
Schumann
M
M
Laag
L
L
Beitz
A
A
Szymanski
C
C
Mest
H J
HJ
D000818:Animals; D001018:Aortic Diseases / Q000503:physiopathology; D001161:Arteriosclerosis / Q000209:etiology / Q000503:physiopathology*; D015992:Body Mass Index; D015519:Bone Density; D004036:Diet, Atherogenic; D005270:Femur Head / Q000503:physiopathology*; D011817:Rabbits
Veränderungen der Spongiosadichte im Femurkopf des Kaninchens bei Atherosklerose.