title: The antimicrobial susceptibility patterns of the Bacteroides fragilis group in the United States, 1987.
abstract: A nationwide survey to monitor the susceptibility of the Bacteroides fragilis group, which began in 1981, was continued during 1987. In addition to the eleven drugs evaluated in 1986, sulbactam, a potent beta-lactamase inhibitor, was tested alone and in combination with ampicillin and cefoperazone. Imipenem, ampicillin/sulbactam, cefoperazone/sulbactam, and ticarcillin/clavulanic acid were the most active newer drugs tested, with less than 1% resistance rates. Chloramphenicol, metronidazole and clindamycin also had excellent activity with resistance rates of 0%, 0%, and 3% respectively. Resistance rates to cefoxitin remained stable at 8%. Ceftizoxime and cefotetan had resistance rates of 26% and 29%, respectively. Rates of resistance varied among different institutions and between the various species.
authors.affiliation: Department of Medicine, New England Medical Center, Boston, MA 02111.
authors.forename: N A
authors.initials: NA
authors.lastname: Cornick
authors.forename: G J
authors.initials: GJ
authors.lastname: Cuchural
authors.forename: D R
authors.initials: DR
authors.lastname: Snydman
authors.forename: N V
authors.initials: NV
authors.lastname: Jacobus
authors.forename: P
authors.initials: P
authors.lastname: Iannini
authors.forename: G
authors.initials: G
authors.lastname: Hill
authors.forename: T
authors.initials: T
authors.lastname: Cleary
authors.forename: J P
authors.initials: JP
authors.lastname: O'Keefe
authors.forename: C
authors.initials: C
authors.lastname: Pierson
authors.forename: S M
authors.initials: SM
authors.lastname: Finegold
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001439:Bacteroides / Q000187:drug effects; D001441:Bacteroides fragilis / Q000187:drug effects*; D004338:Drug Combinations; D004352:Drug Resistance, Microbial; D006801:Humans; D007769:Lactams; D008826:Microbial Sensitivity Tests; D014481:United States
chemical_list: D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D007769:Lactams