Comparative molecular properties of swine and human very low density lipoproteins-apoproteins E and C.
1. By means of 2-dimensional gradient-gel electrophoresis, the very low density lipoproteins (VLDL) apoproteins E and C profiles from human and swine plasma were studied. 2. The molecular properties (isoelectric point and molecular weight) of the VLDL apoproteins and their isoforms were determined and showed many similarities between species. 3. It also appears evident that a previously unrecognized apoprotein (C-III) and several associated isoforms may exist in swine; however, it's mobility on 2-dimensional gradient gels is very similar to Apo C-II.
Stucchi
A F
AF
University of New Hampshire, Department of Animal and Nutritional Sciences, College of Life Sciences and Agriculture, Durham 03824.
Ordovas
J M
JM
Shwaery
G T
GT
Smith
S C
SC
D000818:Animals; D053304:Apolipoprotein C-II; D053305:Apolipoprotein C-III; D001056:Apolipoproteins C / Q000097:blood*; D001057:Apolipoproteins E / Q000097:blood*; D015180:Electrophoresis, Gel, Two-Dimensional; D006801:Humans; D008079:Lipoproteins, VLDL / Q000097:blood*; D013045:Species Specificity; D013552:Swine / Q000097:blood*
D053304:Apolipoprotein C-II; D053305:Apolipoprotein C-III; D001056:Apolipoproteins C; D001057:Apolipoproteins E; D008079:Lipoproteins, VLDL