title: [IgA antibodies in exogenous allergic alveolitis are more specific than IgG antibodies].
abstract: Nineteen sera from patients suffering from extrinsic allergic alveolitis (bird fancier's lung, farmer's lung) and 19 sera from asymptomatic persons demonstrating IgG-antibodies were examined for IgA-antibodies against pigeon serum, Micropolyspora faeni and Aspergillus fumigatus. The IgA-antibodies against pigeon serum and Micropolyspora faeni were less of ten false-positive than the corresponding IgG-antibodies. Hence the IgA-antibodies were more specific than the IgG-antibodies. However, the sensitivity of the IgA-antibodies was lower than that of the IgG-antibodies. On the other hand IgA-antibodies against Aspergillus fumigatus were scarcely more specific than the corresponding IgG-antibodies against pigeon and M. faeni. It would thus seem that IgA-antibodies can supplement the IgG-serodiagnosis of extrinsic allergic alveolitis.
authors.forename: J
authors.initials: J
authors.lastname: Sennekamp
authors.forename: M
authors.initials: M
authors.lastname: Rust
authors.forename: R
authors.initials: R
authors.lastname: Kroidl
authors.forename: M
authors.initials: M
authors.lastname: Spyra
mesh_terms: D000542:Alveolitis, Extrinsic Allergic / Q000175:diagnosis*; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000175:diagnosis; D001716:Bird Fancier's Lung / Q000175:diagnosis; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G
vernacular_title: IgA-Antikörper bei exogen allergischer Alveolitis sind spezifischer als IgG-Antikörper.