title: Hydrocephalus induced by cyclophosphamide in chick embryos.
abstract: Cyclophosphamide was injected into the yolk sac of chick embryos for 6 days (Days 0-5). Embryos collected on the 21st day of incubation had a 37% incidence of hydrocephalus. Agenesis or stenosis of the aqueduct, as well as hypertrophy of the choroid plexus, was observed in 20% of the embryos.
authors.affiliation: Department of Surgery, Banaras Hindu University, Varanasi, India.
authors.forename: S N
authors.initials: SN
authors.lastname: Singh
authors.forename: S
authors.initials: S
authors.lastname: Mohanty
authors.forename: G
authors.initials: G
authors.lastname: Singh
mesh_terms: D000818:Animals; D002642:Chick Embryo; D003520:Cyclophosphamide / Q000633:toxicity*; D006849:Hydrocephalus / Q000139:chemically induced* / Q000473:pathology
chemical_list: D003520:Cyclophosphamide