[Histochemical study of carbohydrate residues in human aortic atherosclerotic lesions by application of lectins].
Carbohydrate residues of various cells in human normal aortic intima, fatty streaks and atherosclerotic plaques were studied with 10 kinds of biotinylated-lectins by immunohistochemical techniques in 10 cases. The results showed that: (1) The amount of carbohydrate residues increased along with the progressing of atherosclerotic lesions. (2) The cells in atherosclerotic lesions could be marked by more than one kind of lectins. (3) Decrease of carbohydrate residues on the endothelial membrane might be considered helpful to the formation of fatty streak.
Zheng
M
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Department of Pathology, Chinese PLA General Hospital.
You
L B
LB
D000368:Aged; D000369:Aged, 80 and over; D001011:Aorta; D001161:Arteriosclerosis / Q000378:metabolism* / Q000473:pathology; D050260:Carbohydrate Metabolism; D004730:Endothelium, Vascular / Q000378:metabolism / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D037102:Lectins; D008875:Middle Aged
D037102:Lectins