title: Localization of ribosomal cistrons at the ultrastructural level by in situ hybridization technique.
abstract: In situ hybridization with 3H 28 S ribosomal RNA at the ultrastructural level shows labelling exclusively over the nucleolus and specifically over the dense nucleolar component (DNC). These findings clearly reveal that the ribosomal cistrons are located in the DNC of the nucleolus.
authors.affiliation: Institute of Cell and Tumor Biology, German Cancer Research Centre, Heidelberg.
authors.forename: S
authors.initials: S
authors.lastname: Ghosh
authors.forename: N
authors.initials: N
authors.lastname: Paweletz
mesh_terms: D000818:Animals; D001345:Autoradiography; D002466:Cell Nucleolus / Q000648:ultrastructure; D002478:Cells, Cultured; D002843:Chromatin / Q000648:ultrastructure; D004275:DNA, Ribosomal / Q000648:ultrastructure*; D005796:Genes; D006367:HeLa Cells; D006801:Humans; D007614:Macropodidae; D009693:Nucleic Acid Hybridization
chemical_list: D002843:Chromatin; D004275:DNA, Ribosomal