[Study of the effect of vinblastine on hair growth in rats].
In the trichological studies on the model of Wistar rats aged 4-5 weeks intraperitoneal vinblastine in doses of 0.008-0.030 mg/100 g of body weight caused initially mixed (dystrophic-telogenic) hair loss. After higher doses and longer drug administration the mechanism of hair loss was transformed to dystrophic. In both forms of hair loss signs of advanced diffuse alopecia were found.
Brzezińska-Wcisło
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I Katedry i Kliniki Dermatologii Sl. AM w Katowicach.
D000505:Alopecia / Q000139:chemically induced*; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D006197:Hair / Q000187:drug effects* / Q000254:growth & development; D007274:Injections, Intraperitoneal; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors; D014747:Vinblastine / Q000008:administration & dosage / Q000009:adverse effects*
D014747:Vinblastine
Badanie wpływu winblastyny na dynamike wzrostu włosów u szczurów.