[A study of the sequelae of perinatal hypoxia and convulsions in full-term newborn infants].
Perinatal hypoxia may result in neuromotor handicaps. The occurrence of convulsions after perinatal hypoxia is regarded as a bad prognostic sign. Thirty-two full-term babies with perinatal hypoxia were studied retrospectively. Post-hypoxic convulsions were seen in 20 newborns. In 26 out of 29 survivors follow-up assessments were made between 2 months and 2 years of age. Severe neuromotor abnormalities were demonstrated in 10 out of 19 patients with post-hypoxic convulsions, whereas no abnormalities were found in 7 patients without convulsions (p = 0.016, Fisher exact test). Although post-hypoxic convulsions are a bad prognostic sign, a number of infants with convulsions appear to develop normally. Further research on prognostic factors concerning neurodevelopment after perinatal hypoxia and convulsions appears indicated.
Groenendaal
F
F
Afd. Kindergeneeskunde, Academisch Ziekenhuis, Rotterdam-Sophia Kinderziekenhuis.
Fetter
W P
WP
Baerts
W
W
D002657:Child Development; D002675:Child, Preschool; D005311:Fetal Hypoxia / Q000150:complications*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008607:Intellectual Disability / Q000209:etiology; D009468:Neuromuscular Diseases / Q000209:etiology*; D012189:Retrospective Studies; D012640:Seizures / Q000150:complications* / Q000523:psychology
Onderzoek naar de gevolgen van perinatale hypoxie en convulsies bij voldragen pasgeborenen.