title: Major burns managed without blood or blood products.
abstract: Four major burns (two flame, one scald, one electrical) were managed without administration of blood or plasma. Serial changes in hemoglobin, and serum albumin and total protein measurements were compared with those of controlled patients matched in age and total body surface area burned who were treated by standard methods. Hemoglobin values were lower but within one standard deviation, although serum protein and albumin measurements fell more than one standard deviation below mean values observed in control patients at comparable times after burn injury. Important treatment principles that were instrumental to recovery include a high-calorie, high-protein diet, iron supplementation, use of pediatric blood sampling techniques, and monitoring for and prophylaxis against infection while allowing eschar to separate spontaneously rather than performing early debridement. Amputation of mummified electrically burned limbs at more proximal levels, including marginally viable muscle, is recommended to minimize infection and decrease blood loss associated with customary conservative serial debridements.
authors.affiliation: Division of Plastic Surgery, Vancouver General Hospital, B.C., Canada.
authors.forename: S
authors.initials: S
authors.lastname: Schlagintweit
authors.forename: C F
authors.initials: CF
authors.lastname: Snelling
authors.forename: E
authors.initials: E
authors.lastname: Germann
authors.forename: R J
authors.initials: RJ
authors.lastname: Warren
authors.forename: D G
authors.initials: DG
authors.lastname: Fitzpatrick
authors.forename: D A
authors.initials: DA
authors.lastname: Kester
authors.forename: B
authors.initials: B
authors.lastname: Foley
mesh_terms: D000328:Adult; D001798:Blood Proteins / Q000032:analysis; D001803:Blood Transfusion; D002056:Burns / Q000097:blood / Q000601:surgery / Q000628:therapy*; D002058:Burns, Electric / Q000601:surgery / Q000628:therapy; D003646:Debridement; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007223:Infant; D008297:Male; D010349:Patient Compliance; D010949:Plasma; D012709:Serum Albumin / Q000032:analysis; D014946:Wound Infection / Q000628:therapy
chemical_list: D001798:Blood Proteins; D006454:Hemoglobins; D012709:Serum Albumin