Case of direct insertion within a chromosome 3 leading to a chromosome 3p duplication in an offspring.
An infant with developmental delay and multiple minor congenital anomalies had a duplication of bands p11.1----p14.2 in 3p. Maternal chromosome studies demonstrated a direct intrachromosomal insertion within chromosome 3p.
Watson
M S
MS
Edward Mallinckrodt Department of Pediatrics, St. Louis Children's Hospital, Washington University School of Medicine, MO 63110.
Dowton
S B
SB
Rohrbaugh
J
J
D002871:Chromosome Banding; D002893:Chromosomes, Human, Pair 3; D006801:Humans; D007223:Infant; D008297:Male; D005810:Multigene Family; D013577:Syndrome