[The interphase death of dividing cells. The relation of interphase death to cell energy requirements].
In experiments with irradiated cells of Chinese hamster and Ehrlich ascites tumor a study was made of the influence of energy provision on their interphase death rate. The presence of the uncoupler of respiration and oxidative phosphorylation--carbonyl cyanide-3-chlorophenylhydrazone--in a medium without glucose was shown to drastically increase the interphase death rate of cells of both types, whereas this effect was not observed in a medium with glucose.
Degtiareva
O V
OV
Korystov
Iu N
IuN
Kublik
L N
LN
Veksler
A M
AM
Dobrovinskaia
O R
OR
Eĭdus
L Kh
LKh
D000818:Animals; D002258:Carbonyl Cyanide m-Chlorophenyl Hydrazone / Q000494:pharmacology; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D004734:Energy Metabolism / Q000187:drug effects / Q000528:radiation effects*; D066298:In Vitro Techniques; D007399:Interphase / Q000187:drug effects / Q000528:radiation effects*
D002258:Carbonyl Cyanide m-Chlorophenyl Hydrazone
Issledovanie interfaznoĭ gibeli deliashchikhsia kletok. Zavisimost' interfaznoĭ gibeli ot énergoobespecheniia kletki.