Asthenozoospermia/teratozoospermia and infertility.
Abnormal spermiograms with asthenozoospermia and teratozoospermia are often classified as subfertile, and the cause of these findings has been obscure. A new method, the 8-h in vitro motility profile test (MPT), showed a significant difference in motility profile between 130 fertile men and men of infertile couples. In the infertile group, an infertility factor (IF) was found. The method was applied to 133 cases, group A, with asthenozoospermia and teratozoospermia. Microbial cultures of semen were also done. Controls, group B, which were 52 males with asthenozoospermia and teratozoospermia, were also investigated with MPT and microbial cultures. All 133 cases of group A had abnormal MPT indicating infertility factor. One hundred and twenty-six cases had positive microbial findings (95%). Long-term treatment with antibiotics of the 126 normalized motility and morphology and eradicated microbes. The MPT was, however, only normalized in 5 cases with two men becoming fathers. The infertility factor, according to the MPT, remained in 128 cases. Though treatment of bacteriospermia has an apparent normalization of parameters as motility, morphology, and cultures, an underlying infertility factor remains in cases of asthenozoospermia and teratozoospermia.
Dahlberg
B
B
Department of Obstetrics and Gynecology, University of Lund, General Hospital, Malmö, Sweden.
D000328:Adult; D006801:Humans; D007248:Infertility, Male / Q000382:microbiology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D013076:Sperm Count; D013081:Sperm Motility; D013997:Time Factors