title: Optic nerve involvement associated with the multiple evanescent white-dot syndrome.
abstract: Five patients presenting with signs and symptoms of primary optic nerve disease were, after careful examination, diagnosed as having the multiple evanescent white-dot syndrome. Optic nerve findings in these patients included disc edema, central visual loss, enlarged blind spots, and other optic nerve field defects. The subtlety of the white spots in some cases made the diagnosis difficult. Multiple evanescent white-dot syndrome should be considered in the differential diagnosis of young, healthy patients who present with unilateral or bilateral optic nerve dysfunction.
authors.affiliation: Department of Ophthalmology, Northwestern University Medical School, Chicago, IL.
authors.forename: D G
authors.initials: DG
authors.lastname: Dodwell
authors.forename: L M
authors.initials: LM
authors.lastname: Jampol
authors.forename: M
authors.initials: M
authors.lastname: Rosenberg
authors.forename: A
authors.initials: A
authors.lastname: Berman
authors.forename: C R
authors.initials: CR
authors.lastname: Zaret
mesh_terms: D000328:Adult; D003951:Diagnostic Errors; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D009900:Optic Nerve / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D010211:Papilledema / Q000473:pathology; D012164:Retinal Diseases / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D013577:Syndrome; D014792:Visual Acuity; D014794:Visual Fields