title: Endoscopic correction of vesicoureteral reflux: our experience with 115 ureters.
abstract: Endoscopic subureteral injection of polytetrafluoroethylene was performed in 115 ureters to correct vesicoureteral reflux. We treated primary reflux in 84 single ureters, 16 duplex ureters and 4 megaureters (grade V), and secondary reflux in 11 ureters associated with neurogenic bladder, uncapped ureteroceles and failed ureteroneocystostomy. Followup evaluation consisted of a voiding cystourethrogram, which was done in the operating room immediately after the endoscopic procedure, ultrasound 1 month postoperatively, and a diethylenetriaminepentaacetic acid renal isotope scan and repeat voiding cystourethrogram 6 months after injection. Grades II to IV primary reflux involving single as well as duplex ureters resolved in 94% and 82%, respectively, of the cases after 1 injection and in 98% and 93% of the cases after 2 or more injections. The severely and chronically dilated ureters did not respond to the treatment.
authors.affiliation: Department of Urology, Shaare Zedek Medical Center, Jerusalem, Israel.
authors.forename: A
authors.initials: A
authors.lastname: Farkas
authors.forename: E Z
authors.initials: EZ
authors.lastname: Moriel
authors.forename: S
authors.initials: S
authors.lastname: Lupa
mesh_terms: D002675:Child, Preschool; D004724:Endoscopy; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D011138:Polytetrafluoroethylene / Q000008:administration & dosage*; D014513:Ureter / Q000002:abnormalities; D014718:Vesico-Ureteral Reflux / Q000209:etiology / Q000628:therapy*
chemical_list: D011138:Polytetrafluoroethylene