title: High versus low ligation of the inferior mesenteric artery in rectal cancer.
abstract: The argument for and against high ligation of the inferior mesenteric artery in rectal cancer has yet to be resolved. Between 1948 and 1983, 4250 patients underwent surgery for rectal carcinoma at St. Mark's Hospital, London. From these, 250 patients were selected who had undergone curative anterior resection of a Dukes' C adenocarcinoma and their records were examined. In 150 (60 per cent) the inferior mesenteric artery was ligated above the origin of the left colic artery. The outcome was analysed using the Dukes', Gastrointestinal Tumour Study Group and Astler-Coller classifications, either alone or in combination. Tumour differentiation and extent of local invasion were also considered. Despite this detailed analysis, no improved survival was seen in patients when the inferior mesenteric artery was ligated above the origin of the left colic artery.
authors.affiliation: Professional Surgical Unit, St. Bartholomew's Hospital, London, UK.
authors.forename: P
authors.initials: P
authors.lastname: Surtees
authors.forename: J K
authors.initials: JK
authors.lastname: Ritchie
authors.forename: R K
authors.initials: RK
authors.lastname: Phillips
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008026:Ligation; D008297:Male; D008638:Mesenteric Arteries / Q000601:surgery*; D008722:Methods; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D015996:Survival Rate