A monocyte-activation inhibitory factor produced by fibroblasts.
Culture media from human fibroblasts pretreated with culture media from activated normal human monocytes partially inhibited the activation of monocytes. Molecular weight of the major inhibitory factor in these culture media was very close to that of human fibroblast interferon. However, an immunoadsorption experiment using monoclonal antibody to human fibroblast interferon failed to adsorb this inhibitory factor.
Baba
T
T
Department of Dermatology, University of Tsukuba, Japan.
Naito
Y
Y
Uyeno
K
K
D002460:Cell Line; D005347:Fibroblasts / Q000276:immunology*; D006801:Humans; D007370:Interferon Type I / Q000276:immunology; D008262:Macrophage Activation; D009000:Monocytes / Q000276:immunology*; D010587:Phagocytosis
D007370:Interferon Type I