title: Thermospray liquid chromatographic-mass spectrometric analysis of castanospermine-related alkaloids in Castanospermum australe.
abstract: Crude sample solution prepared from the seeds of Castanosperum australe was fractionated by preparative liquid chromatography. The fractions thus obtained were subsequently analyzed by means of thermospray liquid chromatography-mass spectrometry (tsp lc-ms). Under the conditions employed, castanospermine [1], 6-epi-castanospermine [2], australine [3], 3,8-di-epi-alexine [4], and fagomine [5] could be separated and detected. The possible structures of other castanospermine-related alkaloids found in the crude sample solution are also discussed.
authors.affiliation: Merrell Dow Research Institute, Cincinnati, Ohio 45215.
authors.forename: T M
authors.initials: TM
authors.lastname: Chen
authors.forename: R C
authors.initials: RC
authors.lastname: George
authors.forename: J L
authors.initials: JL
authors.lastname: Weir
authors.forename: T
authors.initials: T
authors.lastname: Leapheart
mesh_terms: D000470:Alkaloids / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D007212:Indolizines; D010944:Plants / Q000032:analysis*; D054836:Indolizidines
chemical_list: D000470:Alkaloids; D007212:Indolizines; C037806:castanospermine; D054836:Indolizidines