title: Crystallization and preliminary x-ray diffraction study of neurotoxin-I from Naja naja oxiana venom.
abstract: Crystals of the neurotoxin-I (NTX-I) from the venom of the middle Asian cobra Naja naja oxiana have been grown by vapour diffusion and dialysis methods. The crystals belong to space group P2(1)2(1)2 with dimension of a = 25.19 A, b = 75.59 A, c = 36.09 A and diffract to 1.9 A resolution. The asymmetric unit contains one molecule (Vm = 2.2 A/Da). Using the molecule of alpha-cobratoxin (CTX) as a starting model for NTX-I structure determination coordinates of C alpha atoms of the NTX-I molecule were obtained and the position of NTX-I in the unit cell was derived.
authors.affiliation: Institute of Crystallography of the USSR Academy of Sciences, Moscow.
authors.forename: A M
authors.initials: AM
authors.lastname: Mikhailov
authors.forename: A V
authors.initials: AV
authors.lastname: Nickitenko
authors.forename: S D
authors.initials: SD
authors.lastname: Trakhanov
authors.forename: B K
authors.initials: BK
authors.lastname: Vainshtein
authors.forename: E V
authors.initials: EV
authors.lastname: Chetverina
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D003039:Cobra Neurotoxin Proteins; D003461:Crystallography; D004546:Elapid Venoms; D008969:Molecular Sequence Data; D011487:Protein Conformation; D014961:X-Ray Diffraction
chemical_list: D003039:Cobra Neurotoxin Proteins; D004546:Elapid Venoms