Reversible hearing loss in a patient with cryptococcosis.
A 16-year-old girl had hearing loss, paroxysmal tremor, gait disorders, and psychiatric disturbances as the initial manifestations of a cryptococcal meningoencephalitis. Imaging demonstrated an obstructive hydrocephalus, and neuro-otological explorations showed a retrocochlear deafness and diffuse brainstem involvement. Emphasis is on the deafness, which rarely occurs as a presenting symptom in this condition, and on its dramatic improvement following antimycotic therapy.
Mayer
J M
JM
Department of Neurosurgery, Lariboisière, Paris, France.
Chevalier
X
X
Albert
E
E
Casteran
J M
JM
Boutin
B
B
Ponsot
G
G
Dematons
C
C
Cophignon
J
J
D000293:Adolescent; D003453:Cryptococcosis / Q000150:complications*; D005260:Female; D034381:Hearing Loss / Q000209:etiology*; D006801:Humans; D008590:Meningoencephalitis / Q000150:complications*