title: Changes of glycogen and ATP contents of the major cerebral arteries after experimentally produced subarachnoid haemorrhage in the dog.
abstract: The contents of glycogen and ATP in the major cerebral arteries were examined in dogs undergoing subarachnoid haemorrhage (SAH). SAH was produced by a single injection of autologous arterial blood (1 ml/kg body weight) into the cisterna magna. Vertebral angiograms showed biphasic basilar arterial narrowings after the injection of blood: Early arterial narrowing occurred immediately after the injection and continued for a few hours. Late arterial narrowing occurred from Day 1 to Day 14 of post-SAH period, and recovered to the normal level on Day 21 of post-SAH period. The content of glycogen in the large pial arteries significantly decreased from Day 1 to Day 14 and returned to the control level on Day 21. The content of ATP in the large pial arteries also decreased from Day 1 to Day 7 and returned to the control level on Day 14. These results show that energy stores in the major cerebral arteries might be diminished during late arterial narrowing.
authors.affiliation: Department of Neurosurgery, Faculty of Medicine, Kyoto University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Nozaki
authors.forename: S
authors.initials: S
authors.lastname: Okamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Uemura
authors.forename: H
authors.initials: H
authors.lastname: Yanamoto
authors.forename: H
authors.initials: H
authors.lastname: Kikuchi
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism*; D000818:Animals; D001488:Basilar Artery / Q000503:physiopathology; D002536:Cerebral Arteries / Q000503:physiopathology*; D004195:Disease Models, Animal; D004285:Dogs; D005260:Female; D006003:Glycogen / Q000378:metabolism*; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000503:physiopathology*; D011859:Radiography; D013345:Subarachnoid Hemorrhage / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D013997:Time Factors
chemical_list: D000255:Adenosine Triphosphate; D006003:Glycogen