[Clinical cytogenetic studies on patients with cleft lip and/or cleft palate--2. Chromosome analysis of twins].
Development of DNA diagnosis on the monocular level for patients with cleft lip and/or palate may be expected in the near future. The necessary condition for this is to confirm the heredity, elucidate the mode of inheritance and decide on the regional mapping etc. The authors tried a chromosome analysis on a pair of monozygotic twins with cleft lip and palate by using high-resolution banding techniques (about 700 bands). However, chromosome aberration was not confirmed. Therefore, the relation between this congenital anomaly and the chromosome aberration could not be confirmed. In this paper the authors discussed about this problem.
Hashimoto
K
K
Department of Dentistry and Oral Surgery, Hamamatsu University School of Medicine.
Shioda
S
S
Yoshimasu
H
H
Nakamura
K
K
Tamura
T
T
Hagiwara
H
H
Yajima
Y
Y
Furusho
T
T
D002869:Chromosome Aberrations; D002871:Chromosome Banding / Q000379:methods; D002971:Cleft Lip / Q000235:genetics*; D002972:Cleft Palate / Q000235:genetics*; D004200:Diseases in Twins / Q000235:genetics*; D005260:Female; D006801:Humans; D007621:Karyotyping; D014430:Twins, Monozygotic / Q000235:genetics