title: Diffuse angiomatosis of the extremities presenting as a sarcoma.
abstract: Diffuse angiomatosis of the extremities is a rare condition characterized by extensive or multifocal benign mass-forming vascular lesions involving multiple tissue planes; histologically, adipose and fibrous tissue are admixed with vascular elements that vary from capillary proliferations to large vessels that are often structurally abnormal. Although diffuse angiomatosis most likely represents a hamartomatous form of arteriovenous malformation, it behaves clinically as a benign but slowly progressive and unresectable neoplasm. We describe a case of diffuse angiomatosis of the lower extremity that presented clinically as a soft-tissue sarcoma.
authors.affiliation: Department of Pathology, Ohio State University Hospitals, Columbus 43210.
authors.forename: P A
authors.initials: PA
authors.lastname: Allenby
authors.forename: C P
authors.initials: CP
authors.lastname: Boesel
authors.forename: W L
authors.initials: WL
authors.lastname: Marsh
mesh_terms: D000798:Angiomatosis / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007866:Leg / Q000098:blood supply* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012509:Sarcoma / Q000175:diagnosis* / Q000473:pathology; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000473:pathology