Donor selection for single and double lung transplantation. Chest size matching and other factors influencing posttransplantation vital capacity.
In six single lung transplant (SLT) and six double lung transplant (DLT) recipients, the relationships of the recipient's posttransplantation vital capacity (posttx VCR) to the recipient's predicted normal vital capacity (pred VCR) and the donor's predicted normal vital capacity (pred VCD) were investigated. After left SLT the left posttx VCR was correlated with the left predicted VCD (r = 0.83; p less than 0.05); however, no correlation was found between these after DLT. In contrast, there was a tendency toward correlation between the posttx VCR and the predicted VCR after DLT (r = 0.75; p less than 0.1), but no such trend was apparent after SLT. These results suggest that posttx VCR depends primarily on predicted VCD after SLT and on pred VCR after DLT. Therefore, in donor-recipient size matching for lung transplantation a donor with a pred VCD greater than the pred VCR should be chosen for a left SLT recipient, whereas a donor with a pred VCD near the pred VCR would be suitable for a DLT recipient.
Miyoshi
S
S
Division of Thoracic Surgery, General Hospital, Faculty of Medicine, Toronto, Canada.
Schaefers
H J
HJ
Trulock
E P
EP
Yamazaki
F
F
Schreinemakers
H
H
Patterson
G A
GA
Cooper
J
J
D000328:Adult; D001824:Body Constitution; D005260:Female; D006801:Humans; D016040:Lung Transplantation / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011656:Pulmonary Emphysema / Q000601:surgery; D011658:Pulmonary Fibrosis / Q000601:surgery; D013909:Thorax / Q000033:anatomy & histology*; D013997:Time Factors; D014019:Tissue Donors; D014797:Vital Capacity / Q000502:physiology*