title: [Hormonal reaction of steroid-producing glands of female Papio to long-term hypokinesia].
abstract: The endocrine function of steroid-producing glands of hamadryas baboon females exposed to 28-day clinostatic hypokinesia at different stages of the menstrual cycle was investigated. The adrenocortical response to hypokinesia developed in two phases: early stimulation was followed by inhibition of the adrenocortical activity which persisted during the subsequent period of hypokinesia and two weeks after exposure. The degree and duration of the activation effect of hypokinesia were determined by the initial phase of the menstrual cycle: the adrenocortical response during the follicular phase was higher than during the luteal phase. The hormonal function of ovaries was inhibited under the action of hypokinesia. The ovarian response was dependent on the initial phase of the menstrual cycle. Exposure to hypokinesia that began in the follicular phase resulted in a drastic reduction of estradiol while that started at the luteal phase led to a significant decline of progesterone. Monotonously low secretion of ovarian steroids was combined with desynchronosis of their circadian rhythms. Disorders in the function of steroid-producing glands during hypokinesia were transient.
authors.forename: N P
authors.initials: NP
authors.lastname: Goncharov
authors.forename: A N
authors.initials: AN
authors.lastname: Shekhova
mesh_terms: D000305:Adrenal Cortex Hormones / Q000378:metabolism; D000818:Animals; D002940:Circadian Rhythm; D004958:Estradiol / Q000378:metabolism; D005260:Female; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism*; D010053:Ovary / Q000378:metabolism*; D010215:Papio; D010913:Pituitary-Adrenal System / Q000378:metabolism*; D011374:Progesterone / Q000378:metabolism; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000209:etiology / Q000503:physiopathology*; D013997:Time Factors
chemical_list: D000305:Adrenal Cortex Hormones; D011374:Progesterone; D004958:Estradiol
vernacular_title: Gormonal'naia reaktsiia steroidprodutsiruiushchikh zhelez samok pavianov gamadrilov na dlitel'nuiu gipokineziiu.