Persistent Cushing's disease in a patient with invasive pituitary adenoma.
A patient with invasive basophilic pituitary adenoma is described, in whom the hypercortisolaemia and clinical features persisted despite two attempts to reduce the tumour mass by transfrontal pituitary surgery and external beam radiotherapy. The patient responded to oral ketoconazole with clinical and biochemical improvement.
Dash
R J
RJ
Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh.
Khandekar
S
S
Kak
V K
VK
D000230:Adenocarcinoma / Q000097:blood / Q000150:complications* / Q000473:pathology / Q000628:therapy; D000328:Adult; D003131:Combined Modality Therapy; D003480:Cushing Syndrome / Q000097:blood / Q000150:complications* / Q000628:therapy; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007654:Ketoconazole / Q000627:therapeutic use; D010911:Pituitary Neoplasms / Q000097:blood / Q000150:complications* / Q000473:pathology / Q000628:therapy
D007654:Ketoconazole; D006854:Hydrocortisone