Ranitidine-associated recurrent acute pancreatitis.
Ranitidine is a safe, widely prescribed drug for the treatment of peptic ulcer disease and is rarely associated with serious adverse reactions. This report describes a patient who suffered three episodes of acute pancreatitis associated with ranitidine prescribed for duodenal ulcer disease. On each occasion the pancreatitis resolved after withdrawal of ranitidine and recurred upon re-exposure. Underlying biliary and pancreatic disease was excluded. There has been no recurrence of pancreatitis in the five years of follow-up since ranitidine was discontinued.
Herrmann
R
R
Department of Gastroenterology, Royal Melbourne Hospital, Victoria, Australia.
Shaw
R G
RG
Fone
D J
DJ
D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D010195:Pancreatitis / Q000139:chemically induced*; D011899:Ranitidine / Q000009:adverse effects*; D012008:Recurrence
D011899:Ranitidine