title: Treatment of peritonitis due to Curvularia and Trichosporon with amphotericin B.
abstract: Fungal infection is a rare cause of peritonitis among patients receiving continuous ambulatory peritoneal dialysis. Most cases of fungal peritonitis are secondary to candida infection. Two uncommon agents of fungal peritonitis are Curvularia species and Trichosporon beigelii. We report on two patients receiving peritoneal dialysis who presented for medical evaluation within a 1-week period. Fungal culture of the dialysis catheter was positive for Curvularia species in one case and for T. beigelii in the other. Both patients probably had acquired their infections through environmental contamination. Successful treatment of these infections includes removal of the peritoneal dialysis catheter and administration of intravenous amphotericin B.
authors.affiliation: School of Pharmacy, University of North Carolina, Chapel Hill.
authors.forename: M R
authors.initials: MR
authors.lastname: Ujhelyi
authors.forename: R H
authors.initials: RH
authors.lastname: Raasch
authors.forename: C M
authors.initials: CM
authors.lastname: van der Horst
authors.forename: W D
authors.initials: WD
authors.lastname: Mattern
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D003904:Mitosporic Fungi; D009181:Mycoses / Q000188:drug therapy*; D010531:Peritoneal Dialysis, Continuous Ambulatory; D010538:Peritonitis / Q000188:drug therapy* / Q000209:etiology; D014250:Trichosporon
chemical_list: D000666:Amphotericin B