Partial response to lonidamine of advanced bladder carcinoma: a case report.
A 76 year old woman presented with locally advanced papillary transitional cell carcinoma. The patient had elsewhere had trans-urethral resection and radiotherapy and declined salvage cystectomy. She was treated with Lonidamine (150 mg X 3/day p.o. Repeat CT scan after 8 months showed partial remission. This response was unchanged after 28 months Lonidamine therapy.
Lo Re
G
G
Division of Oncology, Centro di Riferimento Oncologico, Aviano.
Veronesi
A
A
Tumolo
S
S
Morassut
S
S
Belmonte
P
P
Francini
M
M
Monfardini
S
S
D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002295:Carcinoma, Transitional Cell / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007191:Indazoles / Q000627:therapeutic use*; D011720:Pyrazoles / Q000627:therapeutic use*; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy*
D000970:Antineoplastic Agents; D007191:Indazoles; D011720:Pyrazoles; C016371:lonidamine