[Different predisposition to the development of spontaneous and induced liver tumors in mice of different strains and their hybrids].
No correlation between the sensitivity to induction of liver tumours by ortho-aminoazotoluene and predisposition to spontaneous development of these tumours was found in mice. Under crossing the predisposition to spontaneous tumours was inherited dominantly, while sensitivity to their induction was inherited by the intermediate type. Spontaneous hepatomas were more frequent in males, whereas induced onesin females of the same genotype.
Kaledin
V I
VI
Serova
I A
IA
Semenova
L A
LA
D000818:Animals; D005260:Female; D005799:Genes, Dominant; D008114:Liver Neoplasms, Experimental / Q000139:chemically induced / Q000209:etiology / Q000235:genetics*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C / Q000235:genetics; D008808:Mice, Inbred CBA / Q000235:genetics; D008815:Mice, Inbred Strains / Q000235:genetics*; D012737:Sex Factors; D009762:o-Aminoazotoluene
D009762:o-Aminoazotoluene
Neodinakovaia predraspolozhennost' k razvitiiu spontannykh i indutsirovannykh opukholeĭ pecheni u mysheĭ raznykh liniĭ i ikh gibridov.