Effects of a sclerosant, ethanolamine, on the venous drainage system of the dog penis.
To explore the possibility of using venous sclerosant therapy to overcome venogenic impotence we studied the effects of ethanolamine on the veins draining the dog penis. Following injection of the sclerosant into the deep dorsal vein radiological and histological evidence of occlusion was obtained but by one month recanalization of thrombi had occurred and collateral venous channels had formed. These findings cast doubt on the effectiveness of this sclerosant as a means of treating impotence.
Tiong
J T
JT
Reproductive Medicine Research Institute, Sir Charles Gairdner Hospital, Nedlands, Australia.
Wisniewski
Z S
ZS
Keogh
E J
EJ
Earle
C M
CM
Tulloch
A G
AG
Lord
D J
DJ
Harvey
J M
JM
Papadimitriou
J M
JM
D000818:Animals; D004285:Dogs; D007172:Erectile Dysfunction / Q000628:therapy*; D008297:Male; D009829:Oleic Acids / Q000494:pharmacology* / Q000627:therapeutic use; D010413:Penis / Q000098:blood supply*; D012597:Sclerosing Solutions / Q000494:pharmacology* / Q000627:therapeutic use; D015911:Sclerotherapy; D014680:Veins / Q000187:drug effects
D009829:Oleic Acids; D012597:Sclerosing Solutions; C033343:ethanolamine oleate