title: Low calcium diet in idiopathic urolithiasis: a risk factor for osteopenia as great as in primary hyperparathyroidism.
abstract: The bone mineral content of the radius was measured in 32 male renal stone formers, 18 of them presenting with idiopathic urolithiasis and 14 with primary hyperparathyroidism, a disease known to disturb bone metabolism. The idiopathic stone formers had been on regular treatment with a low calcium diet. The bone mineral content of the radius was reduced to a similar level in both groups of patients. The data suggest that idiopathic stone formers on a low calcium diet are at risk of osteopenia; the factors which could lead to a negative calcium balance included uncompensated renal hypercalciuria, hypophosphataemia and exaggerated serum levels of 1,25-dihydroxyvitamin D. To treat idiopathic hypercalciuria, thiazide diuretics, which reduce the renal excretion of calcium and have been shown to be beneficial for bone, seem safer than a low calcium diet.
authors.affiliation: Department of Internal Medicine, Brugmann Hospital, Brussels, Belgium.
authors.forename: M
authors.initials: M
authors.lastname: Fuss
authors.forename: T
authors.initials: T
authors.lastname: Pepersack
authors.forename: P
authors.initials: P
authors.lastname: Bergman
authors.forename: T
authors.initials: T
authors.lastname: Hurard
authors.forename: J
authors.initials: J
authors.lastname: Simon
authors.forename: J
authors.initials: J
authors.lastname: Corvilain
mesh_terms: D000328:Adult; D000368:Aged; D015519:Bone Density; D001851:Bone Diseases, Metabolic / Q000209:etiology*; D002136:Calcium, Dietary / Q000008:administration & dosage*; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D014545:Urinary Calculi / Q000178:diet therapy* / Q000209:etiology / Q000378:metabolism
chemical_list: D002136:Calcium, Dietary