Spontaneous neuronal firing patterns in the occipital cortex of developing rats.
Spontaneous action potentials have been recorded in the cerebral cortex of developing rats under chloral hydrate anaesthesia. These "spike-trains" were subjected to a multivariate analysis of parameters describing different aspects of temporal patterning within each train. Three parameters which reflected clustering of action potentials in, respectively, the range of: (i) milliseconds (the modal interval, derived from the interval histograms); (ii) seconds (the mean "burst period", i.e. the time elapsing between the onset of successive clusters of relatively short intervals); and (iii) minutes (the coefficient of variation for the number of spikes in consecutive 2 min time bins) showed distinctive developmental patterns.
Corner
M A
MA
Netherlands Institute for Brain Research, Amsterdam.
Mirmiran
M
M
D000200:Action Potentials; D000375:Aging; D000704:Analysis of Variance; D000818:Animals; D002540:Cerebral Cortex / Q000254:growth & development / Q000502:physiology; D005260:Female; D008297:Male; D009474:Neurons / Q000502:physiology*; D009778:Occipital Lobe / Q000254:growth & development* / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors