[Seasonal rhythm of melatonin in manic depressive patients].
Melatonin is secreted by the pineal gland with a circadian and a circannual rhythm. For some authors the circadian rhythm is modified during depressive states. The present study evaluates the melatonin circannual rhythm in five manic-depressive patients. Each patient is clinically and biologically evaluated every month during one year. The results of the present study show a lack of clinical relapse and a lack of seasonal variation of plasma melatonin level.
Fanget
F
F
Service Hospitalo-Universitaire, C.H.S. Le Vinatier, Bron.
Terra
J L
JL
Dalery
J
J
Brun
J
J
Claustrat
B
B
Marie-Cardine
M
M
Guyotat
J
J
D000328:Adult; D000704:Analysis of Variance; D001714:Bipolar Disorder / Q000097:blood* / Q000378:metabolism / Q000503:physiopathology; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008550:Melatonin / Q000097:blood* / Q000502:physiology; D010507:Periodicity; D010870:Pineal Gland / Q000503:physiopathology; D012008:Recurrence
D008550:Melatonin
Rythme circannuel de mélatonine chez des patients maniaco-dépressifs.