title: Human sex-chromosome-specific repeats within a region of pseudoautosomal/Yq homology.
abstract: Several categories of human X-Y homologous DNA sequences have been recognized. We report that a locus (DXYS77) approximately 14 kb distal to the pseudoautosomal boundary (PAB) is 93% identical in nucleotide sequence to a locus (DYS148) on the long arm of the Y chromosome (Yq). Within this segment of pseudoautosomal/Yq homology we identified a member of a family of repeats that are concentrated in Xp22.3 and in the euchromatic portion of the Y chromosome. The repeat sequence structure--a dimer bounded by short terminal repeats--is reminiscent of retroposons derived from RNA polymerase III transcripts.
authors.affiliation: Whitehead Institute, Cambridge, Massachusetts.
authors.forename: E M
authors.initials: EM
authors.lastname: Fisher
authors.forename: T
authors.initials: T
authors.lastname: Alitalo
authors.forename: S W
authors.initials: SW
authors.lastname: Luoh
authors.forename: A
authors.initials: A
authors.lastname: de la Chapelle
authors.forename: D C
authors.initials: DC
authors.lastname: Page
mesh_terms: D001483:Base Sequence; D006801:Humans; D008969:Molecular Sequence Data; D012091:Repetitive Sequences, Nucleic Acid; D012689:Sequence Homology, Nucleic Acid; D014960:X Chromosome; D014998:Y Chromosome