[The kallikrein-kinin system in experimental uveitis].
The author analyzes changes in the activities of the kallikrein-kinin system (KKS) parameters over the course of experimental toxic allergic uveitis induced in 24 animals; the reference group consisted of 8 intact animals. Clinical examinations of the eyes were parallelled by biochemical analyses that revealed a significant activation of the blood serum and vitreous KKS, the degree of this activation correlating with uveitis severity. No normalization of KKS parameters was associated with complete clinical cure, this being possibly due to a chronic course of the condition and thus valuable for pathogenetically oriented therapy.
Aktasheva
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D000818:Animals; D002265:Carboxylic Ester Hydrolases / Q000378:metabolism*; D004789:Enzyme Activation; D007610:Kallikreins / Q000378:metabolism*; D011288:Prekallikrein / Q000378:metabolism; D011817:Rabbits; D014605:Uveitis / Q000201:enzymology*; D014822:Vitreous Body / Q000201:enzymology*
D011288:Prekallikrein; D002265:Carboxylic Ester Hydrolases; C019763:benzoylarginine ethyl esterase; D007610:Kallikreins
Kallikrein-kininovaia sistema pri éksperimental'nom uveite.