The relationship between certain blood constituents in cows with milk fever and the response following treatment with calcium borogluconate solutions.
The association between the concentrations of various blood constituents and the responses of cows with milk fever following calcium borogluconate therapy was determined using analysis of variance. In cows which had not received herdsman treatment prior to sampling (n = 63), plasma potassium was the only constituent with a significant effect (p less than 0.01), the mean concentrations for cows classified as unassisted, assisted, or delayed, recoveries, and deaths ranging down from 4.3 to 2.8 mmol/l, respectively. In cows which had received treatment prior to sampling (n = 55) those making unassisted recoveries had significantly lower mean concentrations of serum total calcium than those making assisted recoveries (1.3 v 1.9 mmol/l, respectively, p less than 0.05), and cows making delayed recoveries had significantly lower mean plasma inorganic phosphate concentrations (0.3 mmol/l) than those making unassisted and assisted recoveries (both 0.7 mmol/l, p less than 0.05) and those subsequently dying (1.2 mmol/l, p less than 0.01). Response was not dependent on plasma potassium concentrations in the treated group of cows, and plasma sodium, serum magnesium, and erythrocyte sodium concentrations were not significant in either group of cows.
Fenwick
D C
DC
Department of Physiology and Pharmacology, University of Queensland, St Lucia.
D000704:Analysis of Variance; D000818:Animals; D001888:Boric Acids / Q000627:therapeutic use*; D002118:Calcium / Q000097:blood; D002417:Cattle; D002418:Cattle Diseases / Q000097:blood* / Q000188:drug therapy; D004912:Erythrocytes / Q000032:analysis; D005260:Female; D008274:Magnesium / Q000097:blood; D010319:Parturient Paresis / Q000097:blood* / Q000188:drug therapy; D010758:Phosphorus / Q000097:blood; D011188:Potassium / Q000097:blood; D011247:Pregnancy; D012964:Sodium / Q000097:blood; D012996:Solutions
D001888:Boric Acids; D012996:Solutions; D010758:Phosphorus; C034286:borogluconate; D012964:Sodium; D008274:Magnesium; D011188:Potassium; D002118:Calcium