title: [Diagnostic and therapeutic aspects in Klinefelter's syndrome. Our experience].
abstract: We present a retrospective study of 30 new cases of Klinefelter's syndrome and set forth our customary diagnostic and therapeutic schedule. We analyse the results obtained and single out the fact that 100% of the patients displayed high gonadotropins and 45% apparent plasmatic testosterone normality at the time of diagnosis. There is a relationship between lower semen fructose concentration, smaller volume of semen and higher degree of hypoandrogenism in Klinefelter's syndrome. Long duration hormonal treatment with testosterone esters is effective in improving the physical psychic and sexual state of patients. The interval between the last administration and the control hormone determination should be uniform for correct result evaluation.
authors.affiliation: Servicio de Urología, Hospital Miguel Servel, Zaragoza.
authors.forename: C A
authors.initials: CA
authors.lastname: Allepuz Losa
authors.forename: J
authors.initials: J
authors.lastname: Sánchez García
authors.forename: I
authors.initials: I
authors.lastname: Rodríguez Vela
authors.forename: A
authors.initials: A
authors.lastname: Villanueva Benedicto
authors.forename: L
authors.initials: L
authors.lastname: Rioja Sanz
mesh_terms: D000293:Adolescent; D000328:Adult; D006801:Humans; D007621:Karyotyping; D007713:Klinefelter Syndrome / Q000097:blood / Q000188:drug therapy / Q000235:genetics; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013739:Testosterone / Q000627:therapeutic use
chemical_list: D013739:Testosterone
vernacular_title: Aspectos diagnósticos y terapéuticos en el síndrome de Klinefelter. Nuestra experiencia.