title: [Monoclonal antibodies of the IPO series in studying and diagnosing malignant lymphoproliferative diseases].
abstract: The authors have developed a panel of monoclonal antibodies (MCA) of IPO series (Institute of Problems of Oncology, Kiev). RPMI-1788 cell line, Daudi, as well as splenocytes of a patient with hairy-cell leukemia were used for immunization of mice. It has been shown that IPO-3, IPO-10 and IPO-24 MCA are directed against differentiation antigens of human B-lymphocytes. IPO-4 MCA reveal the antigen of activated T- and B-cells. IPO-5 and IPO-20 MCA recognize HLA-ABC, while IPO-37 a common leucocytic antigen. IPO-38 MCA are directed against the nuclear antigen. The possibilities of using IPO MCA in hematology have been discussed.
authors.forename: S P
authors.initials: SP
authors.lastname: Sidorenko
authors.forename: E P
authors.initials: EP
authors.lastname: Vetrova
authors.forename: O V
authors.initials: OV
authors.lastname: Iurchenko
authors.forename: L N
authors.initials: LN
authors.lastname: Shlapatskaia
authors.forename: A G
authors.initials: AG
authors.lastname: Berdova
authors.forename: A M
authors.initials: AM
authors.lastname: Elenskaia
authors.forename: M D
authors.initials: MD
authors.lastname: Bal'shin
authors.forename: D F
authors.initials: DF
authors.lastname: Gluzman
mesh_terms: D000047:Academies and Institutes; D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis / Q000276:immunology; D015703:Antigens, CD / Q000276:immunology; D003937:Diagnosis, Differential; D006801:Humans; D007938:Leukemia / Q000175:diagnosis* / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology; D008223:Lymphoma / Q000175:diagnosis* / Q000276:immunology; D008495:Medical Oncology; D051379:Mice; D014455:Ukraine
chemical_list: D000911:Antibodies, Monoclonal; D015703:Antigens, CD
vernacular_title: Monoklonal'nye antitela serii IPO v izuchenii i diagnostike zlokachestvennykh limfoproliferativnykh zabolevaniĭ.