[A case of a gastric cancer patient with high serum pepsinogen levels at relapse].
A rare case of a 68-year-old female cancer patient with an extremely high serum level of pepsinogens (PG) at relapse is presented. She had stage 3 Borrmann 3 type gastric cancer which was a poorly differentiated adenocarcinoma. Her postoperative serum PG levels had been within normal limits (23.0 ng/ml for PG-I and 3.2 ng/ml for PG-II), but at the time of the peritoneal relapse they were 5,630 ng/ml and 3,380 ng/ml, respectively. After was chemotherapy initiated, her serum PG levels decreased in parallel with an improvement of her clinical status. Immunohistochemical examination with monoclonal antibodies revealed PG-I and PG-II production in the primary and the metastatic lesions.
Kimura
Y
Y
Dept. of Radiology, Ehime Univ. Med. School.
Fujii
T
T
Miyagawa
N
N
Tanada
S
S
Hamamoto
K
K
Kimura
S
S
D000230:Adenocarcinoma / Q000201:enzymology* / Q000473:pathology / Q000601:surgery; D000368:Aged; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D010435:Pepsinogens / Q000097:blood*; D013274:Stomach Neoplasms / Q000201:enzymology* / Q000473:pathology / Q000601:surgery
D010435:Pepsinogens