title: Mouse strain differences in plasma corticosterone following uncontrollable footshock.
abstract: Exposure to acute inescapable footshock provoked marked increases of plasma corticosterone concentrations in six strains of mice (A/J, Balb/cByJ, C57BL/6J, C3H/HeJ, DBA/2J and CD-1). However, the magnitude of the increase, as well as the time required for corticosterone to return to control values, varied appreciably across strains. Moreover, it appeared that the strain-specific corticoid increases ordinarily observed after acute shock were also evidence following a chronic stressor regimen. The data were related to previously observed strain differences in stressor-induced alterations of brain norepinephrine, dopamine and serotonin, as well as variations in performance in several behavioral paradigms.
authors.affiliation: Department of Psychology, Carleton University, Ottawa, Ontario, Canada.
authors.forename: N
authors.initials: N
authors.lastname: Shanks
authors.forename: J
authors.initials: J
authors.lastname: Griffiths
authors.forename: S
authors.initials: S
authors.lastname: Zalcman
authors.forename: R M
authors.initials: RM
authors.lastname: Zacharko
authors.forename: H
authors.initials: H
authors.lastname: Anisman
mesh_terms: D000818:Animals; D003345:Corticosterone / Q000097:blood*; D004597:Electroshock; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D013045:Species Specificity; D013312:Stress, Physiological / Q000097:blood* / Q000209:etiology
chemical_list: D003345:Corticosterone