Piroxicam suppositories in the treatment of osteoarthritis of the knee joint.
The subjects were 231 patients aged 16 to 75 years with osteoarthritis of the knee joint. Each patient received 20 mg of piroxicam daily as a suppository administered before sleep; 75% of the patients were treated for 14 days or longer. Overall treatment outcome was excellent in 34% according to physicians' ratings and in 36% according to the patients' self-ratings, good in 39% and 41%, fair in 22% and 17%, and unimproved in 5% and 7%, respectively. Side effects were reported by 3% of the patients. It is concluded that treatment of osteoarthritis with piroxicam suppositories is safe and effective.
Hatori
M
M
Department of Orthopaedic Surgery, Tohoku University, School of Medicine, Sendai, Japan.
Sakurai
M
M
Kokubun
S
S
Rijal
K P
KP
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007719:Knee Joint; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy*; D010894:Piroxicam / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D013488:Suppositories
D013488:Suppositories; D010894:Piroxicam