title: [Exogenous allergic asthma following pectin exposure--a new occupational allergen].
abstract: In a 51-year-old male worker, workplace-related dyspnoea in the sense of bronchial asthma, was observed. On the basis of the medical history, the results of serology, inhalatory provocation and histamine release tests, despite a negative skin test, pectins were established to be the precipitating substances; in experiments on animals (Wistar rats), the instillation of pectins led to the development of bronchiolitis. An exogenous, allergic asthma following exposure to pectin may be considered to have been proven.
authors.affiliation: Medizinische Klinik Forschungsinstitut Borstel.
authors.forename: W
authors.initials: W
authors.lastname: Westphal
authors.forename: E
authors.initials: E
authors.lastname: Müller
authors.forename: K
authors.initials: K
authors.lastname: Schübeler
authors.forename: W M
authors.initials: WM
authors.lastname: Becker
authors.forename: E
authors.initials: E
authors.lastname: Fasske
authors.forename: M
authors.initials: M
authors.lastname: Schlaak
mesh_terms: D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D000542:Alveolitis, Extrinsic Allergic / Q000209:etiology*; D000818:Animals; D001985:Bronchial Provocation Tests; D004391:Dust / Q000009:adverse effects*; D005511:Food Handling; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000209:etiology*; D010368:Pectins / Q000009:adverse effects*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D000395:Air Pollutants, Occupational; D004391:Dust; D010368:Pectins
vernacular_title: Exogen-allergisches Asthma nach Pektin-Exposition--ein neues Berufsallergen.