title: Biochemical properties of mammalian DNA ligase I and the molecular defect in Bloom's syndrome.
authors.affiliation: Imperial Cancer Research Fund, South Mimms, Herts, U.K.
authors.forename: A E
authors.initials: AE
authors.lastname: Tomkinson
authors.forename: D D
authors.initials: DD
authors.lastname: Lasko
authors.forename: T
authors.initials: T
authors.lastname: Lindahl
mesh_terms: D000249:Adenosine Monophosphate / Q000378:metabolism; D000818:Animals; D001816:Bloom Syndrome / Q000201:enzymology / Q000235:genetics*; D002417:Cattle; D002460:Cell Line; D004247:DNA / Q000378:metabolism; D000072481:DNA Ligase ATP; D011088:DNA Ligases / Q000172:deficiency* / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism; D004261:DNA Replication; D006801:Humans; D008214:Lymphocytes / Q000201:enzymology; D011118:Polynucleotide Ligases / Q000172:deficiency*; D012854:Sister Chromatid Exchange; D013950:Thymus Gland / Q000201:enzymology
chemical_list: C000607892:LIG1 protein, human; D000249:Adenosine Monophosphate; D004247:DNA; D011088:DNA Ligases; D011118:Polynucleotide Ligases; D000072481:DNA Ligase ATP