HLA-B27 positive idiopathic acute anterior uveitis: a unique manifestation of subclinical gut inflammation.
Ileocolonoscopy was performed on 2 HLA-B27 positive patients with idiopathic acute anterior uveitis neither of whom had articular or intestinal complaints. Microscopic examination of the biopsy specimens revealed the presence of chronic inflammatory lesions in the ileum. Since these lesions have also been described in other forms of spondyloarthropathy, we postulate the presence of gut inflammation was related to the uveitis.
Mielants
H
H
Department of Rheumatology, Ghent University Hospital, Belgium.
Veys
E M
EM
Verbraeken
H
H
De Vos
M
M
Cuvelier
C
C
D000208:Acute Disease; D000328:Adult; D003113:Colonoscopy; D005260:Female; D005767:Gastrointestinal Diseases / Q000150:complications / Q000473:pathology; D015796:HLA-B27 Antigen / Q000276:immunology*; D006801:Humans; D007082:Ileum / Q000473:pathology; D007249:Inflammation / Q000150:complications / Q000473:pathology; D014606:Uveitis, Anterior / Q000209:etiology / Q000276:immunology* / Q000473:pathology
D015796:HLA-B27 Antigen