Toxicity studies with potassium embelate, a new analgesic compound.
Potassium embelate, 2,5-dihydroxy, 3-undecyl-1, 4-benzoquinone, from Embelia ribes Burm. was subjected to toxicity evaluation which included subacute, chronic, reproductive toxicity testing and teratological investigations in laboratory animals (mice, rats and monkeys). The results did not indicate adverse effects suggesting that potassium embelate is a safe compound.
Johri
R K
RK
Regional Research Laboratory, Jammu-Tawi, India.
Dhar
S K
SK
Pahwa
G S
GS
Sharma
S C
SC
Kaul
J L
JL
Zutshi
U
U
D000014:Abnormalities, Drug-Induced; D000700:Analgesics / Q000633:toxicity*; D000818:Animals; D016227:Benzoquinones; D001835:Body Weight / Q000187:drug effects; D005260:Female; D005298:Fertility / Q000187:drug effects; D008253:Macaca mulatta; D008297:Male; D051379:Mice; D010946:Plants, Medicinal; D011809:Quinones / Q000633:toxicity*; D051381:Rats
D000700:Analgesics; D016227:Benzoquinones; D011809:Quinones; C010945:embelin