Haloperidol-induced torsades de pointes.
A patient had torsades de pointes ventricular tachycardia related to psychotherapy with haloperidol in conventional doses. The QT interval was prolonged, and shortened after the cessation of the medication and infusion of isoproterenol. Concomitantly, torsades de pointes bursts disappeared. The observation might contribute to the understanding of the mechanism of sudden death of patients during pharmacologic psychotherapy.
Kriwisky
M
M
Heart Institute, Edith Wolfson Medical Center, Holon, Israel.
Perry
G Y
GY
Tarchitsky
D
D
Gutman
Y
Y
Kishon
Y
Y
D000328:Adult; D004562:Electrocardiography; D006220:Haloperidol / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D012559:Schizophrenia / Q000188:drug therapy; D013610:Tachycardia / Q000139:chemically induced* / Q000175:diagnosis
D006220:Haloperidol