Extramedullary plasmacytoma of the thyroid associated with a serum monoclonal gammopathy.
Extramedullary plasmacytoma is a malignant plasma cell dyscrasia that is most commonly found in the head and neck. Progression to disseminated disease in the form of multiple myeloma occurs in 17% to 32% of cases. Herein, we describe a patient with extramedullary plasmacytoma of the thyroid gland in whom a serum monoclonal gammopathy resolved with surgery and irradiation of the primary. Although rare, this diagnosis should be considered in patients presenting with obstructive thyromegaly and autoimmune thyroiditis.
Rubin
J
J
Department of Otolaryngology, University of Pittsburgh School of Medicine, PA.
Johnson
J T
JT
Killeen
R
R
Barnes
L
L
D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D010265:Paraproteinemias / Q000209:etiology*; D010954:Plasmacytoma / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D013964:Thyroid Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000628:therapy