title: Doppler echocardiographic assessment of time to peak velocity in the aorta and pulmonary artery of small for gestational age fetuses.
abstract: The time to peak velocity was measured at the level of the ascending aorta and pulmonary artery by Doppler echocardiography in 38 small-for-gestational age (SGA) fetuses before and during maternal hyperoxygenation. The values were compared to a reference range derived from the study of 142 appropriate-for-gestational age (AGA) fetuses. In the SGA fetuses the time to peak velocity at the level of pulmonary artery was significantly lower and at the level of the aorta significantly higher than in AGA fetuses. During maternal hyperoxygenation the aortic time to peak velocity decreased towards normal range but there was no significant change at the level of the pulmonary artery. These results may indicate variations of aortic and pulmonary pressures in SGA fetuses that can be partially modified by maternal hyperoxygenation and which may be associated with changes in the peripheral resistance of the cerebral circulation.
authors.affiliation: Department of Obstetrics and Gynecology, Università Cattolica S. Cuore, Roma, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Rizzo
authors.forename: D
authors.initials: D
authors.lastname: Arduini
authors.forename: C
authors.initials: C
authors.lastname: Romanini
authors.forename: S
authors.initials: S
authors.lastname: Mancuso
mesh_terms: D001013:Aorta, Thoracic / Q000502:physiology; D001783:Blood Flow Velocity; D015150:Echocardiography, Doppler; D005314:Embryonic and Fetal Development / Q000502:physiology*; D005260:Female; D005865:Gestational Age; D006340:Heart Rate, Fetal; D006801:Humans; D010100:Oxygen / Q000008:administration & dosage; D011247:Pregnancy; D011651:Pulmonary Artery / Q000502:physiology; D012044:Regression Analysis
chemical_list: D010100:Oxygen