Hydrocephalus induced by cyclophosphamide in chick embryos.
Cyclophosphamide was injected into the yolk sac of chick embryos for 6 days (Days 0-5). Embryos collected on the 21st day of incubation had a 37% incidence of hydrocephalus. Agenesis or stenosis of the aqueduct, as well as hypertrophy of the choroid plexus, was observed in 20% of the embryos.
Singh
S N
SN
Department of Surgery, Banaras Hindu University, Varanasi, India.
Mohanty
S
S
Singh
G
G
D000818:Animals; D002642:Chick Embryo; D003520:Cyclophosphamide / Q000633:toxicity*; D006849:Hydrocephalus / Q000139:chemically induced* / Q000473:pathology
D003520:Cyclophosphamide