title: Systemic complications associated with retinal cryoablation for retinopathy of prematurity.
abstract: Eighty infants with proliferative retinopathy of prematurity (ROP) were treated with peripheral retinal cryoablation. Among the serious systemic complications encountered were three instances of respiratory arrest and one of cardiorespiratory arrest. Recommendations that may help prevent these adverse systemic effects in premature infants include: (1) avoidance of excess subconjunctival anesthetic doses, (2) preoperative administration of systemic atropine to minimize the oculocardiac reflex, (3) consideration of an analgesic agent to decrease the pain and exhaustion, and (4) cardiorespiratory monitoring in a hospital setting, with an intravenous line in place, at the time of treatment.
authors.affiliation: Retina Service, Wills Eye Hospital, Philadelphia, PA.
authors.forename: G C
authors.initials: GC
authors.lastname: Brown
authors.forename: W S
authors.initials: WS
authors.lastname: Tasman
authors.forename: M
authors.initials: M
authors.lastname: Naidoff
authors.forename: D B
authors.initials: DB
authors.lastname: Schaffer
authors.forename: G
authors.initials: G
authors.lastname: Quinn
authors.forename: V K
authors.initials: VK
authors.lastname: Bhutani
mesh_terms: D000777:Anesthetics / Q000008:administration & dosage; D001285:Atropine / Q000627:therapeutic use; D002675:Child, Preschool; D003452:Cryosurgery / Q000009:adverse effects*; D005260:Female; D006323:Heart Arrest / Q000209:etiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007431:Intraoperative Complications / Q000188:drug therapy / Q000517:prevention & control; D008297:Male; D011379:Prognosis; D012131:Respiratory Insufficiency / Q000209:etiology*; D012178:Retinopathy of Prematurity / Q000601:surgery*
chemical_list: D000777:Anesthetics; D001285:Atropine