title: Biochemical predictors for osteoporotic fractures in elderly Chinese--a longitudinal study.
abstract: In a longitudinal study of 283 elderly subjects aged 60 years or over living in the community, 9 subjects (7 women and 2 men) developed osteoporosis-related fractures in 30 months. These subjects initially had higher random urinary hydroxyproline/creatinine and calcium/creatinine ratios, and lower plasma 25-hydroxyvitamin D concentrations. These biochemical variables may be useful predictors of osteoporosis-related fractures and may provide a suitable community screening method to identify those most at risk.
authors.affiliation: Department of Medicine, Chinese University of Hong Kong.
authors.forename: J
authors.initials: J
authors.lastname: Woo
authors.forename: E
authors.initials: E
authors.lastname: Lau
authors.forename: R
authors.initials: R
authors.lastname: Swaminathan
authors.forename: C P
authors.initials: CP
authors.lastname: Pang
authors.forename: D
authors.initials: D
authors.lastname: MacDonald
mesh_terms: D015652:25-Hydroxyvitamin D 2 / Q000097:blood; D000368:Aged; D044466:Asian People; D015415:Biomarkers / Q000097:blood / Q000652:urine; D002118:Calcium / Q000652:urine; D015331:Cohort Studies; D003404:Creatinine / Q000652:urine; D003625:Data Collection; D005260:Female; D050723:Fractures, Bone / Q000453:epidemiology / Q000209:etiology*; D006723:Hong Kong; D006801:Humans; D006909:Hydroxyproline / Q000652:urine; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications* / Q000453:epidemiology; D012307:Risk Factors
chemical_list: D015415:Biomarkers; D015652:25-Hydroxyvitamin D 2; D003404:Creatinine; D006909:Hydroxyproline; D002118:Calcium