[The functional topography of the digestive enzymes in the gastrointestinal tract and in nondigestive organs (liver, kidney) in the ontogeny of rats and the effect of inducing agents].
Activities of the digestive enzymes (lactase, maltase, saccharose, di-, tri- and aminopeptidases, alkaline and acid phosphatase) in the gastrointestinal tract, the kidney and the liver in one-day-old and adult rats as well as in 10-day-old rats after injections of hydrocortisone (H) or thyroxine (T4) were determined. On the basis of the results obtained it is summarized that (1) high levels of the digestive enzyme activities are observed in the nondigestive organs in immature and adult rats; (2) H induces the enzyme activities in the small intestine more than in other organs; T4 does not influence the activities of the most of enzymes studied both in the digestive and in the nondigestive organs; (3) high activities of a number of enzymes in the colon in one-day-old rats implies its involvement in the digestion at early stages of the ontogenesis.
Nikitina
A A
AA
Egorova
V V
VV
Iezuitova
N N
NN
Timofeeva
N M
NM
Ugolev
A M
AM
D000135:Acid Phosphatase / Q000032:analysis / Q000096:biosynthesis; D000375:Aging / Q000187:drug effects / Q000378:metabolism*; D000469:Alkaline Phosphatase / Q000032:analysis / Q000096:biosynthesis; D000626:Aminopeptidases / Q000032:analysis / Q000096:biosynthesis; D000818:Animals; D000831:Animals, Newborn; D004063:Digestion / Q000187:drug effects / Q000502:physiology*; D004064:Digestive System / Q000187:drug effects / Q000201:enzymology*; D004790:Enzyme Induction / Q000187:drug effects; D006026:Glycoside Hydrolases / Q000032:analysis / Q000096:biosynthesis; D007668:Kidney / Q000187:drug effects / Q000201:enzymology*; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D051381:Rats
D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D006026:Glycoside Hydrolases; D000626:Aminopeptidases
Funktsional'naia topografiia pishchevaritel'nykh fermentov v zheludochno-kishechnom trakte i nepishchevaritel'nykh organakh (pechen', pochka) v ontogeneze u krys i vliianie nekotorykh indutsiruiushchikh agentov.