title: Morphologic study of changes of collagenous tissue in the amnion and cervix during prostaglandin-induced abortion and delivery.
abstract: Marked dissociation of the cervical collagenous tissue during prostaglandin-induced abortion is well recognized, but the response of collagenous tissue of the amnion to prostaglandin treatment is not known. A morphologic study of amniotic collagenous tissue was performed after prostaglandin-induced abortion and prostaglandin-induced term delivery. The collagenous fibers of the amnion were found to be closely packed with no ground substances and formed in a thick layer. Cervical collagenous tissue of the same patients showed a marked dissociation of fibers and abundant ground substance. The fetus was often delivered within a complete sac at midtrimester. These findings suggest differences in collagenous tissue responses to prostaglandin treatment between the amnion and cervix.
authors.affiliation: Department of Obstetrics and Gynecology, Kyoto University School of Medicine, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Manabe
authors.forename: Y
authors.initials: Y
authors.lastname: Yoshida
mesh_terms: D000028:Abortion, Induced; D000650:Amnion / Q000166:cytology* / Q000378:metabolism / Q000648:ultrastructure; D002584:Cervix Uteri / Q000166:cytology* / Q000378:metabolism / Q000648:ultrastructure; D003094:Collagen / Q000378:metabolism*; D036861:Delivery, Obstetric; D005260:Female; D005347:Fibroblasts / Q000166:cytology / Q000648:ultrastructure; D006801:Humans; D008854:Microscopy, Electron; D011247:Pregnancy; D011453:Prostaglandins / Q000494:pharmacology*
chemical_list: D011453:Prostaglandins; D003094:Collagen