Recent developments in clinical immunology.
Developments in the area of molecular biology and gene cloning have led to the better understanding of the pathophysiology of immune responses that in turn have been instrumental in the delineation of defects in a variety of human disorders and the formulation of therapeutic approaches. In this review, areas of the T cell receptors, signal transduction, transfer of human immune response in SCID mouse model, gene therapy, adoptive immunotherapy, and immunotoxins as therapeutic modalities are discussed.
Gupta
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Division of Basic and Clinical Immunology, University of California, Irvine 92717.
D000818:Animals; D015316:Genetic Therapy; D006801:Humans; D007109:Immunity; D007111:Immunity, Cellular; D007116:Immunization, Passive; D000922:Immunotoxins / Q000627:therapeutic use; D051379:Mice; D008817:Mice, Mutant Strains; D011948:Receptors, Antigen, T-Cell / Q000276:immunology; D015398:Signal Transduction / Q000276:immunology
D000922:Immunotoxins; D011948:Receptors, Antigen, T-Cell