title: Neuropeptide K-like immunoreactivity in human dental pulp.
abstract: Nerve fibres displaying such immunoreactivity were revealed by indirect immunofluorescence. Neuropeptide K-like immunoreactive fibres, entering the pulp within large nerve trunks, were distributed around blood vessels as well as in the stroma. Some immunoreactive fibres were also observed in the para-odontoblastic region. In view of the biological activity of neuropeptide K, it is tentatively proposed that it may act in the dental pulp as a regulatory peptide involved in neurogenic inflammation, blood flow regulation and sensory transmission.
authors.affiliation: Istituto di Istologia ed Embriologia, University of Pavia, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Casasco
authors.forename: A
authors.initials: A
authors.lastname: Calligaro
authors.forename: D R
authors.initials: DR
authors.lastname: Springall
authors.forename: M
authors.initials: M
authors.lastname: Casasco
authors.forename: P
authors.initials: P
authors.lastname: Poggi
authors.forename: K L
authors.initials: KL
authors.lastname: Valentino
authors.forename: J M
authors.initials: JM
authors.lastname: Polak
mesh_terms: D001808:Blood Vessels / Q000294:innervation; D003782:Dental Pulp / Q000032:analysis* / Q000098:blood supply / Q000294:innervation; D006801:Humans; D007150:Immunohistochemistry; D009412:Nerve Fibers / Q000032:analysis / Q000648:ultrastructure; D009479:Neuropeptides / Q000032:analysis*; D015320:Tachykinins
chemical_list: D009479:Neuropeptides; D015320:Tachykinins; C045206:neuropeptide K