title: [I-125 labeling of human, rat, and bovine fibrinogen].
abstract: Human, rat and bovine fibrinogen were radioiodinated using a modified chloramine-T method under mild labelling conditions and with a satisfactory labelling efficiency. The 125I-human, rat and bovine fibrinogen preparations obtained met the requirements with respect to clottability, low content of 125Iodide as well as stability in vitro and in vivo. SDS-PAGE mobility demonstrated that the integrity of the fibrinogen molecule was not affected by the labelling procedure.
authors.affiliation: Institut für Pharmakologie und Toxikologie, Medizinischen Akademie Erfurt.
authors.forename: M
authors.initials: M
authors.lastname: Richter
authors.forename: U
authors.initials: U
authors.lastname: Cyranka
authors.forename: F
authors.initials: F
authors.lastname: Markwardt
mesh_terms: D000818:Animals; D002417:Cattle; D002855:Chromatography, Thin Layer; D004591:Electrophoresis, Polyacrylamide Gel; D005340:Fibrinogen / Q000032:analysis*; D006801:Humans; D007457:Iodine Radioisotopes; D007553:Isotope Labeling; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D007457:Iodine Radioisotopes; D005340:Fibrinogen
vernacular_title: 125I-Markierung von Human-, Ratten- und Rinderfibrinogen.