title: Population data on acute infantile and chronic childhood spinal muscular atrophy in Warsaw.
abstract: This study provides epidemiological data on acute infantile (ASMA) and chronic childhood spinal (CSMA) muscular atrophy in Warsaw for the period 1976-1985. All calculations are based on the assumption that ASMA and CSMA result from mutations at two different gene loci. The incidence of ASMA and CSMA was 1 in 19474 live births with a corresponding gene and carrier frequency of 714 x 10(-5) and 1 in 70, respectively. The prevalence of CSMA for the year 1985 was 1.26 x 10(-5). These figures are higher than in similar studies in other countries. This fact might be connected with the careful ascertainment in this study.
authors.affiliation: Department of Neurology, Polish Academy of Sciences, Warsaw.
authors.forename: A W
authors.initials: AW
authors.lastname: Spiegler
authors.forename: I
authors.initials: I
authors.lastname: Hausmanowa-Pertrusewicz
authors.forename: J
authors.initials: J
authors.lastname: Borkowska
authors.forename: A
authors.initials: A
authors.lastname: Kłopocka
mesh_terms: D002908:Chronic Disease; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D015994:Incidence; D008297:Male; D009134:Muscular Atrophy, Spinal / Q000453:epidemiology* / Q000235:genetics; D011044:Poland / Q000453:epidemiology; D015995:Prevalence; D014897:Spinal Muscular Atrophies of Childhood / Q000453:epidemiology / Q000235:genetics