title: Electroretinographic responses of the short-wavelength-sensitive cones.
abstract: An electroretinographic response of the human short wavelength (S) cone system can be distinguished from that of the longer wavelength (L or M) cone system by using ganzfeld short-wavelength stimulation at relatively high levels of retinal adaptation. The S cone response has both an a- and b-wave component in its ERG, both of which are slower than those of the L or M cone response at the same level of retinal adaptation. Proof that this is the S cone response is obtained by action spectra and by examination of a sex-linked achromat who is known to have only S cone and rod vision. This approach allows the simultaneous and rapid assessment of both the S and the L or M cone systems in the human retina using conventional electroretinogram (ERG) equipment, ganzfeld blue flashes on a white background, and computer averaging.
authors.affiliation: Department of Ophthalmology, Columbia University, New York, NY 10032.
authors.forename: P
authors.initials: P
authors.lastname: Gouras
authors.forename: C J
authors.initials: CJ
authors.lastname: MacKay
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003117:Color Vision Defects / Q000503:physiopathology; D004596:Electroretinography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010775:Photic Stimulation; D010786:Photoreceptor Cells / Q000502:physiology*; D014792:Visual Acuity