title: Cerebrospinal fluid creatine kinase activity in horses with central nervous system disease: 69 cases (1984-1989).
abstract: The CSF creatine kinase (CK) activity was determined in 70 CSF samples from 69 horses with CNS disease. Abnormal values (greater than or equal to 1 IU/L) were determined from 32 CSF samples, and normal values (less than 1 IU/L) were found in 38 samples. Increased CK activity was most frequently associated with a diagnosis of equine protozoal myelitis; CK activity was not increased in 11 horses with cervical compressive myelopathy. Other diagnoses, in which CSF CK activity was increased included trauma (n = 1), idiopathic epilepsy (n = 2), botulism (n = 2), articular facet fracture (n = 1), intervertebral disk protrusion (n = 1), and toxemia (n = 1).
authors.affiliation: Department of Large Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg, VA 24061.
authors.forename: M O
authors.initials: MO
authors.lastname: Furr
authors.forename: R D
authors.initials: RD
authors.lastname: Tyler
mesh_terms: D000818:Animals; D002493:Central Nervous System Diseases / Q000134:cerebrospinal fluid / Q000662:veterinary*; D003402:Creatine Kinase / Q000134:cerebrospinal fluid*; D006734:Horse Diseases / Q000134:cerebrospinal fluid*; D006736:Horses; D012189:Retrospective Studies
chemical_list: D003402:Creatine Kinase