title: Angiotrophic lymphoma. Presentation in uterine vessels with cytogenetic studies.
abstract: An unusual case of angiotrophic lymphoma diagnosed initially in the uterus is described. Immunohistochemical studies documented the intravascular tumor cells in the myometrium to be of B lymphocytic origin. The patient's bone marrow was hypercellular, and cytogenetic studies of the aspirate revealed a subpopulation of cells with multiple clonal chromosomal abnormalities. To our knowledge, this is the first case to document abnormal cytogenetic findings in this uncommon malignancy.
authors.affiliation: Department of Pathology, University of Kentucky Medical Center, Lexington 40536-0093.
authors.forename: D D
authors.initials: DD
authors.lastname: Davey
authors.forename: R
authors.initials: R
authors.lastname: Munn
authors.forename: L W
authors.initials: LW
authors.lastname: Smith
authors.forename: M L
authors.initials: ML
authors.lastname: Cibull
mesh_terms: D001402:B-Lymphocytes; D001853:Bone Marrow / Q000473:pathology; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007150:Immunohistochemistry; D007621:Karyotyping; D008223:Lymphoma / Q000235:genetics / Q000473:pathology*; D008875:Middle Aged; D009360:Neoplastic Cells, Circulating / Q000473:pathology; D014594:Uterine Neoplasms / Q000235:genetics / Q000473:pathology*; D014599:Uterus / Q000098:blood supply