title: [Nuclear DNA content in tumors of the colon and rectum. Relationship between ploidy and site of the neoplasm].
abstract: The DNA distribution pattern was determined 30 colo-rectal carcinomas. The DNA content in individual cells was measured according to a cytophotometric method based on light transmission measurement of Feulgen-stained nuclei. The DNA non diploid carcinomas were significantly more common from the left (descending and sigmoid) colon and rectum (P = 0.0002). No relationship existed between DNA pattern and age, sex, Dukes' stage, tumor grade.
authors.affiliation: Cattedra di Patologia Speciale Chirurgica II, Università degli Studi di Genova.
authors.forename: G C
authors.initials: GC
authors.lastname: Larghero
authors.forename: M
authors.initials: M
authors.lastname: Ottonello
authors.forename: T
authors.initials: T
authors.lastname: Testa
authors.forename: S
authors.initials: S
authors.lastname: Scarpettini
authors.forename: A
authors.initials: A
authors.lastname: Abbondati
authors.forename: G
authors.initials: G
authors.lastname: Capponi
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics*; D000328:Adult; D000368:Aged; D003110:Colonic Neoplasms / Q000235:genetics*; D004273:DNA, Neoplasm / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011003:Ploidies; D012004:Rectal Neoplasms / Q000235:genetics*
chemical_list: D004273:DNA, Neoplasm
vernacular_title: Contenuto nucleare di DNA nei tumori del colon-retto. Rapporto tra ploidia e sede della neoplasia.