[Relation of circulating immunocomplexes and epileptic discharges in the electroencephalograms (EEG) of epileptic patients].
The relation between the EEG manifestations and the contents of the circulating immune complexes (CIC) in 160 epileptic patients was studied. It was found that the CIC contents of the patients with epileptic discharges (P less than 0.01). It was not related to the sexual distinction, age, type of seizures frequency of attacks treatment, and length of the time between the last attacks and the time for the measurements. Even in the same patient, the CIC content would be at a high level when epileptic discharges appeared, and decreased when epileptic discharges disappeared in the EEG observed. It was surmised that this might be due to some biological active factors released during the epileptic discharges of the brain which destroyed the integrity of the blood brain barrier so that large quantity of brain antigen entered the systemic circulation and combine with corresponding antibodies thus leading to the increase of CIC.
Yang
J
J
Neurological Research Unit, Affiliated Hospital of Qingdao Medical College.
D000293:Adolescent; D000328:Adult; D000936:Antigen-Antibody Complex / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004827:Epilepsy / Q000276:immunology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D000936:Antigen-Antibody Complex