title: [Treatment of bone infection by plaster of Paris pellets impregnated with antibiotics].
abstract: In two prospective clinical trials, the authors treated 83 chronic osteomyelitis from various origins by sequestrectomy completed with insertion of Plaster of Paris pellets impregnated with antibiotics. After a review of the experimental and clinical reports on the subjects, the authors give their results: 61.5% of healings and 38.5% of failures. Because of the small number of cases, it was not possible to find out an explanation for this fair results. However wide extension of the lesions, which is frequent in chronic haematogenous osteomyelitis, seems to be a contraindication to the technics. The authors conclude to the necessity of carrying up new experiments with new antibiotics and large series of patients in order to point out the righted indications of the method.
authors.affiliation: Service de Chirurgie Orthopédique A, Hôpital Cochin, Paris.
authors.forename: J
authors.initials: J
authors.lastname: Evrard
authors.forename: O
authors.initials: O
authors.lastname: Kerri
authors.forename: M
authors.initials: M
authors.lastname: Martini
authors.forename: O
authors.initials: O
authors.lastname: Conort
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D002133:Calcium Sulfate; D002908:Chronic Disease; D004343:Drug Implants; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009985:Orthopedics / Q000379:methods; D010000:Osteitis / Q000188:drug therapy* / Q000382:microbiology; D010019:Osteomyelitis / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D004343:Drug Implants; D002133:Calcium Sulfate
vernacular_title: Traitement des infections osseuses par linguettes de plâtre de Paris imprégnées d'antibiotiques.