title: Piroxicam suppositories in the treatment of osteoarthritis of the knee joint.
abstract: The subjects were 231 patients aged 16 to 75 years with osteoarthritis of the knee joint. Each patient received 20 mg of piroxicam daily as a suppository administered before sleep; 75% of the patients were treated for 14 days or longer. Overall treatment outcome was excellent in 34% according to physicians' ratings and in 36% according to the patients' self-ratings, good in 39% and 41%, fair in 22% and 17%, and unimproved in 5% and 7%, respectively. Side effects were reported by 3% of the patients. It is concluded that treatment of osteoarthritis with piroxicam suppositories is safe and effective.
authors.affiliation: Department of Orthopaedic Surgery, Tohoku University, School of Medicine, Sendai, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Hatori
authors.forename: M
authors.initials: M
authors.lastname: Sakurai
authors.forename: S
authors.initials: S
authors.lastname: Kokubun
authors.forename: K P
authors.initials: KP
authors.lastname: Rijal
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007719:Knee Joint; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy*; D010894:Piroxicam / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D013488:Suppositories
chemical_list: D013488:Suppositories; D010894:Piroxicam