The antimicrobial susceptibility patterns of the Bacteroides fragilis group in the United States, 1987.
A nationwide survey to monitor the susceptibility of the Bacteroides fragilis group, which began in 1981, was continued during 1987. In addition to the eleven drugs evaluated in 1986, sulbactam, a potent beta-lactamase inhibitor, was tested alone and in combination with ampicillin and cefoperazone. Imipenem, ampicillin/sulbactam, cefoperazone/sulbactam, and ticarcillin/clavulanic acid were the most active newer drugs tested, with less than 1% resistance rates. Chloramphenicol, metronidazole and clindamycin also had excellent activity with resistance rates of 0%, 0%, and 3% respectively. Resistance rates to cefoxitin remained stable at 8%. Ceftizoxime and cefotetan had resistance rates of 26% and 29%, respectively. Rates of resistance varied among different institutions and between the various species.
Cornick
N A
NA
Department of Medicine, New England Medical Center, Boston, MA 02111.
Cuchural
G J
GJ
Snydman
D R
DR
Jacobus
N V
NV
Iannini
P
P
Hill
G
G
Cleary
T
T
O'Keefe
J P
JP
Pierson
C
C
Finegold
S M
SM
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001439:Bacteroides / Q000187:drug effects; D001441:Bacteroides fragilis / Q000187:drug effects*; D004338:Drug Combinations; D004352:Drug Resistance, Microbial; D006801:Humans; D007769:Lactams; D008826:Microbial Sensitivity Tests; D014481:United States
D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D007769:Lactams