title: The tubular maximum for calcium reabsorption in patients with chronic active thoracic sarcoidosis.
abstract: The tubular maximum for calcium reabsorption (TmCa) was evaluated in 52 patients with chronic active thoracic sarcoidosis. Hypercalcaemia was found in five patients (9.6%). The mean serum calcium value of 2.54 +/- 0.18 mmol.l-1 in patients with sarcoidosis was significantly higher than that obtained in the control group (2.42 +/- 0.11 mmol.l-1). The mean TmCa in patients with sarcoidosis (2.11 +/- 0.26 mmol.l-1 glomerular filtrate (GF] was not statistically different from the mean TmCa for the group of healthy subjects (2.18 +/- 0.23 mmol.l-1 GF). Urinary sodium corrected TmCa in both groups of patients was affected in a similar way. Our study demonstrates for the first time that there is no increase in TmCa in patients with chronic active thoracic sarcoidosis. Hypercalcaemia is not a result of an increased TmCa.
authors.affiliation: Third Dept of Internal Medicine, Charles University, Faculty of Medicine, Prague, Czechoslovakia.
authors.forename: P D
authors.initials: PD
authors.lastname: Broulik
authors.forename: V
authors.initials: V
authors.lastname: Votava
authors.forename: V
authors.initials: V
authors.lastname: Pacovsky
mesh_terms: D000328:Adult; D000368:Aged; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology; D002118:Calcium / Q000097:blood / Q000378:metabolism* / Q000652:urine; D002908:Chronic Disease; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D006934:Hypercalcemia / Q000453:epidemiology / Q000209:etiology; D007684:Kidney Tubules / Q000378:metabolism*; D007958:Leukocyte Count; D008171:Lung Diseases / Q000150:complications / Q000175:diagnosis / Q000378:metabolism*; D008214:Lymphocytes; D008297:Male; D008875:Middle Aged; D012507:Sarcoidosis / Q000150:complications / Q000175:diagnosis / Q000378:metabolism*
chemical_list: D002118:Calcium