[Good response to azidothymidine in 3 patients with vacuolar myelopathy].
We report 3 drug abusers with human immunodeficiency virus (HIV) infection who had presented with myelopathic symptoms. A diagnosis of vacuolar myelopathy associated with HIV was made. The patients had a favorable response to azidothymidine. They were followed up as outpatients, and they showed a significant clinical improvement within 1-3 months of therapy. They remained stable 11 months afterwards. The patients with this type of disease may benefit from azidothymidine therapy.
von Wichmann
M A
MA
Unidad de Enfermedades infecciosas, Hospital Nuestra Señora de Aránzazu, San Sebastián.
Iribarren
J A
JA
Arrizabalaga
J
J
Bernardo
P
P
Garde
C
C
Rodríguez-Arrondo
F J
FJ
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D013118:Spinal Cord Diseases / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D014617:Vacuoles; D015215:Zidovudine / Q000627:therapeutic use*
D015215:Zidovudine
Buena respuesta a azidotimidina en tres pacientes con mielopatía vacuolar.