title: HLA typing in actinic prurigo.
abstract: Thirty-two actinic prurigo patients of Cree ancestry underwent human lymphocyte antigen (HLA) typing and were compared with 32 control subjects of Cree ancestry. We found a significantly increased frequency of HLA-A24 and Cw4 antigens and a significant decrease in the frequency of the A3 antigen in actinic prurigo patients. These HLA associations may be helpful in determining whether actinic prurigo is a distinct disease or a variant of polymorphous light eruption.
authors.affiliation: Department of Medicine, University of Saskatchewan, Saskatoon, Canada.
authors.forename: D P
authors.initials: DP
authors.lastname: Sheridan
authors.forename: P R
authors.initials: PR
authors.lastname: Lane
authors.forename: J
authors.initials: J
authors.lastname: Irvine
authors.forename: M J
authors.initials: MJ
authors.lastname: Martel
authors.forename: D J
authors.initials: DJ
authors.lastname: Hogan
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D007198:Indians, North American; D008297:Male; D008875:Middle Aged; D010787:Photosensitivity Disorders / Q000235:genetics / Q000276:immunology*; D011536:Prurigo / Q000235:genetics / Q000276:immunology*; D012525:Saskatchewan
chemical_list: D006680:HLA Antigens