Immunodiagnosis of human cysticercosis in cerebrospinal fluid. Antigens from murine Taenia crassiceps cysticerci effectively substitute those from porcine Taenia solium.
Tapeworm antigens from Taenia crassiceps performed as well as those antigens from Taenia solium in an enzyme-linked immunosorbent assay for the detection of Cysticercus antibodies in 96 cerebrospinal fluid samples from patients with neurocysticercosis and in 96 CSF samples from patients with other varied neurological ailments. Thus, this manageable murine model of experimental cysticercosis solved the problem of antigen supply for clinical and epidemiological applications, and it provided an immediate means of abundant production of antigens for the wide distribution and standardization of immunodiagnostic tests for cysticercosis.
Larralde
C
C
Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico City.
Sotelo
J
J
Montoya
R M
RM
Palencia
G
G
Padilla
A
A
Govezensky
T
T
Diaz
M L
ML
Sciutto
E
E
D000818:Animals; D000947:Antigens, Helminth / Q000032:analysis*; D003551:Cysticercosis / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D003552:Cysticercus / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D013621:Taenia / Q000276:immunology*
D000947:Antigens, Helminth