Distribution of immunoglobulin G and E antibody levels to salivary gland extracts of Aedes albopictus (Diptera: Culicidae) in several age groups of a Japanese population.
A total of 300 Japanese people from 2 wk to 98 yr of age were tested for immunoglobulin (Ig) G and E antibodies to salivary gland extracts of Aedes albopictus (Skuse) mosquitoes by an enzyme-linked immunosorbent assay. Almost all had IgG antibodies. The mean IgG antibody levels increased with age up to 2 yr and then leveled off, indicating a relatively frequent exposure to Aedes-mosquito bites. Distribution patterns of IgE antibody levels were similar among all age groups. The antibody status involved in mosquito allergy, especially in the five-stage sequence of skin reactivity, is discussed.
Konishi
E
E
Department of Medical Zoology, Kobe University School of Medicine, Japan.
D000293:Adolescent; D000328:Adult; D000330:Aedes / Q000276:immunology*; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D007223:Infant; D007231:Infant, Newborn; D007564:Japan; D008297:Male; D008875:Middle Aged; D012469:Salivary Glands / Q000276:immunology
D007074:Immunoglobulin G; D007073:Immunoglobulin E