[The duration and strength of postvaccinal measles immunity].
A prolonged immunoepidemiological follow-up of a large group of children immunized against measles revealed a high epidemiological efficacy of a single vaccination. Cases of measles were registered only among those vaccinees in whose blood sera no specific hemagglutinins were detectable by titration with 4 hemagglutinating units of measles antigen prior to the disease. The study showed that groups of children seronegative with respect to measles appeared, as a rule, after unsatisfactory immunization and not due to loss of postvaccinal immunity with time. Properly immunized children in whom the formation of antimeasles antibodies had occurred in response to the injection of live measles vaccine retained postvaccinal immunity for more that 15 years (the term of observation).
Bolotovskiĭ
V M
VM
Gelikman
B G
BG
Auzinia
A V
AV
Glinskaia
E V
EV
D000914:Antibodies, Viral / Q000097:blood; D000917:Antibody Formation / Q000276:immunology; D000918:Antibody Specificity / Q000276:immunology; D002648:Child; D005500:Follow-Up Studies; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D008457:Measles / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control*; D008458:Measles Vaccine / Q000276:immunology*; D008459:Measles virus / Q000276:immunology; D016036:Seroepidemiologic Studies; D013997:Time Factors; D014586:USSR / Q000453:epidemiology
D000914:Antibodies, Viral; D008458:Measles Vaccine
Dlitel'nost' i napriazhennost' postvaktsinal'nogo protivokorevogo immuniteta.