title: [Primary hypothyroidism associated with changes in the sella turcica and the hypophyseal function. Description of 5 cases].
abstract: We report 5 clinical cases of primary hypothyroidism or premixedema with associated pituitary lesion. Before treatment was started with L-thyroixine (L-T4) pituitary hormones were examined and an X-ray of the silla turca as well as a CT scan of the hypophysis (CTH) was done. Once supplementation treatment was started hormone levels normalized. In three out of the 5 cases, CT scan done after establishing therapy, showed empty silla turca. Therefore, me stress the importance of closely examining the pituitary gland in patients with untreated primary hypothyroidism.
authors.affiliation: Hospital Universitario de Granada, Section de Endocrinología.
authors.forename: M
authors.initials: M
authors.lastname: Muñoz Torres
authors.forename: S
authors.initials: S
authors.lastname: Céspedes Mas
authors.forename: J
authors.initials: J
authors.lastname: Díaz de Madrid
authors.forename: A
authors.initials: A
authors.lastname: Vidal Puig
authors.forename: E
authors.initials: E
authors.lastname: Alvarez Cienfuegos
authors.forename: F
authors.initials: F
authors.lastname: Escobar Jiménez
mesh_terms: D000328:Adult; D004652:Empty Sella Syndrome / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000150:complications* / Q000188:drug therapy; D008297:Male; D010900:Pituitary Diseases / Q000150:complications / Q000188:drug therapy; D013974:Thyroxine / Q000627:therapeutic use
chemical_list: D013974:Thyroxine
vernacular_title: Hipotiroidismo primario asociado a alteraciones de la silla turca y de la función hipofisaria. Descripción de cinco casos.