Biochemical predictors for osteoporotic fractures in elderly Chinese--a longitudinal study.
In a longitudinal study of 283 elderly subjects aged 60 years or over living in the community, 9 subjects (7 women and 2 men) developed osteoporosis-related fractures in 30 months. These subjects initially had higher random urinary hydroxyproline/creatinine and calcium/creatinine ratios, and lower plasma 25-hydroxyvitamin D concentrations. These biochemical variables may be useful predictors of osteoporosis-related fractures and may provide a suitable community screening method to identify those most at risk.
Woo
J
J
Department of Medicine, Chinese University of Hong Kong.
Lau
E
E
Swaminathan
R
R
Pang
C P
CP
MacDonald
D
D
D015652:25-Hydroxyvitamin D 2 / Q000097:blood; D000368:Aged; D044466:Asian People; D015415:Biomarkers / Q000097:blood / Q000652:urine; D002118:Calcium / Q000652:urine; D015331:Cohort Studies; D003404:Creatinine / Q000652:urine; D003625:Data Collection; D005260:Female; D050723:Fractures, Bone / Q000453:epidemiology / Q000209:etiology*; D006723:Hong Kong; D006801:Humans; D006909:Hydroxyproline / Q000652:urine; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications* / Q000453:epidemiology; D012307:Risk Factors
D015415:Biomarkers; D015652:25-Hydroxyvitamin D 2; D003404:Creatinine; D006909:Hydroxyproline; D002118:Calcium