Isolation of glutamyltaurine from bovine brains and proof of its gamma-linkage by the B/E linked scan SIMS technique.
We isolated a glutamyltaurine from bovine brains and determined its structure as gamma-glutamyltaurine (gamma-Glu-Tau; glutaurine) by use of a new mass spectrometric technique [B/E linked scan sputtered ion mass spectrometry (SIMS)], which we have recently shown to be useful for distinguishing the gamma- from the alpha-isomer of glutamyl-dipeptides. Neither the alpha-isomer of glutamyltaurine nor any aspartyltaurines could be detected in bovine brain.
Nakamura
K
K
Institute of Bio-Active Science, Nippon Zoki Pharmaceutical Co., Ltd., Hyogo, Japan.
Higashiura
K
K
Nishimura
N
N
Yamamoto
A
A
Tooyama
I
I
Kimura
H
H
Ienaga
K
K
D000818:Animals; D001923:Brain Chemistry; D002417:Cattle; D005973:Glutamine / Q000031:analogs & derivatives* / Q000302:isolation & purification; D013058:Mass Spectrometry; D015394:Molecular Structure; D013654:Taurine / Q000031:analogs & derivatives* / Q000302:isolation & purification
D005973:Glutamine; D013654:Taurine; C020903:glutaurine