title: Resection guided by antibodies (REGAJ): a diagnostic procedure during second-look operation in ovarian cancer patients.
abstract: A hand-held probe has been used to localise the 131I-labelled antibody OC125 during second-look operation (SLO) in 22 ovarian cancer patients. In six patients microscopic cancer was detected with the procedure and a further six patients with areas of increased radioactivity during SLO developed recurrent disease within 1-4 months. We suggest examining resection guided by antibodies as a possible means of removing antigen-producing cancerous tissues during surgery.
authors.affiliation: Department of Obstetrics and Gynecology, University of Erlangen-Nürnberg, FRG.
authors.forename: W
authors.initials: W
authors.lastname: Jäger
authors.forename: H
authors.initials: H
authors.lastname: Feistel
authors.forename: E M
authors.initials: EM
authors.lastname: Paterok
authors.forename: G
authors.initials: G
authors.lastname: Ronay
authors.forename: A H
authors.initials: AH
authors.lastname: Tulusan
authors.forename: F
authors.initials: F
authors.lastname: Wolf
authors.forename: N
authors.initials: N
authors.lastname: Lang
mesh_terms: D000911:Antibodies, Monoclonal; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis*; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000601:surgery; D011877:Radionuclide Imaging / Q000379:methods*; D012086:Reoperation
chemical_list: D000911:Antibodies, Monoclonal; D015295:Antigens, Tumor-Associated, Carbohydrate