Progressive dystonia following resuscitation from cardiac arrest.
We report a case of a 55-year-old man in whom progressive extrapyramidal disease developed nearly 1 year after resuscitation from cardiopulmonary arrest. Parkinsonian features evolved within 3 months, and progressive generalized dystonia developed after 11 months. CT and MRI revealed bilateral basal ganglia infarction. Autopsy after 4 years of illness showed bilateral basal ganglia necrosis with preserved corticospinal tracts. These findings support earlier suggestions that postinfarction dystonia is mediated by a pyramidal system lacking normal striatal control.
Boylan
K B
KB
Department of Neurology, School of Medicine, University of California, San Francisco 94143.
Chin
J H
JH
DeArmond
S J
SJ
D004421:Dystonia / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D006323:Heart Arrest / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012151:Resuscitation; D013997:Time Factors; D014057:Tomography, X-Ray Computed