Ovarian clear-cell carcinoma producing estradiol and human chorionic gonadotropin.
A case of clear-cell carcinoma of the ovary in a 52-year-old woman having an unusual menstrual history is presented. Serum concentrations of human chorionic gonadotropin (hCG) and estradiol were 120 mIU/ml and 86 pg/ml, respectively, while the serum FSH level was 43 mIU/ml. Immunohistochemistry of the tumor revealed positive staining for both hCG and estradiol in the tumor cells.
Kobayashi
M
M
Department of Obstetrics and Gynecology, Wakayama Medical College, Japan.
Hamada
H
H
Yamoto
M
M
Nakano
R
R
D000230:Adenocarcinoma / Q000378:metabolism* / Q000473:pathology; D006063:Chorionic Gonadotropin / Q000378:metabolism*; D004958:Estradiol / Q000378:metabolism*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000378:metabolism* / Q000473:pathology; D010053:Ovary / Q000378:metabolism / Q000473:pathology
D006063:Chorionic Gonadotropin; D004958:Estradiol