Interstitial cystitis treated with intravesical doxorubicin.
Three patients with interstitial cystitis diagnosed on the basis of clinical symptoms, classic endoscopic findings, and a typical histologic picture were treated with intravesical doxorubicin. All 3 patients showed remarkable improvement, as manifested by complete clearance of irritative bladder symptoms and healing of ulceration. Doxorubicin therefore may be the breakthrough drug for interstitial cystitis.
Khanna
O P
OP
Department of Surgery (Division of Urology), Hahnemann University, Philadelphia, Pennsylvania.
Loose
J H
JH
D000283:Administration, Intravesical; D000328:Adult; D003556:Cystitis / Q000188:drug therapy* / Q000473:pathology; D004317:Doxorubicin / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D004317:Doxorubicin