Fatal pneumococcal bacteremia with disseminated intravascular coagulation and Waterhouse-Friderichsen syndrome in a vaccinated splenectomized adult. Case report.
Fatal pneumococcal bacteremia, disseminated intravascular coagulation and Waterhouse Friderichsen syndrome in a vaccinated, splenectomized adult were caused by serotype 22F (Danish classification), which was not included in the vaccine. Revaccination with a 23-valent pneumococcal vaccine and antibiotic prophylaxis are advocated for patients who have undergone splenectomy.
Lindblad
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BE
Second University Clinic of Internal Medicine, Kommunehospitalet, Aarhus, Denmark.
Lindblad
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LN
D001428:Bacterial Vaccines; D004211:Disseminated Intravascular Coagulation / Q000209:etiology*; D005260:Female; D006801:Humans; D008589:Meningococcal Infections / Q000209:etiology*; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000209:etiology*; D022242:Pneumococcal Vaccines; D018805:Sepsis / Q000209:etiology*; D012703:Serotyping; D013156:Splenectomy; D013296:Streptococcus pneumoniae / Q000145:classification*; D014611:Vaccination; D014884:Waterhouse-Friderichsen Syndrome / Q000209:etiology*
D001428:Bacterial Vaccines; D022242:Pneumococcal Vaccines