Molecular biology as a tool in the study of glucose transport and metabolism.
The rationale for pharmacologically increasing the transcription of the insulin responsive-glucose transporter of muscle and fat in diabetes is presented. The experimental approaches to achieve such a goal are outlined as well as a delineation of the assumptions and potential problems associated with this approach.
Foley
J E
JE
Diabetes Department, Sandoz Pharmaceutical Corp., E. Hanover, N.J. 07036.
Bell
P A
PA
D000273:Adipose Tissue / Q000378:metabolism; D000818:Animals; D001692:Biological Transport; D003920:Diabetes Mellitus / Q000235:genetics / Q000378:metabolism*; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D009004:Monosaccharide Transport Proteins / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D012333:RNA, Messenger / Q000378:metabolism; D051381:Rats
D009004:Monosaccharide Transport Proteins; D012333:RNA, Messenger; D005947:Glucose