[The effect of combined drug treatment on rheologic properties of the blood in patients with disordered circulatory encephalopathy].
The effect of vasoactive agents, nootropic drugs and cerebrolysin on blood viscosity was studied in 128 patients with atherosclerotic disordered circulatory encephalopathy. Vasoactive and nootropic agents excluding cerebrolysin reduced blood viscosity, spontaneous aggregation of erythrocytes and thrombocytes. The most pronounced effect in reducing blood viscosity and aggregation properties of erythrocytes produced by sermion, pentoxyphyllin and pyriditol while the spontaneous aggregation of thrombocytes was reduced by calcium antagonists (corinfar, phynoptin) and pentoxyphyllin. Cerebrolysin produced a marked effect on erythrocytes, elevation of blood viscosity. Hence, its use in patients with ischemic blood circulation disorders requires cautious approach.
Ishchenko
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MM
Ostrovskaia
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OS
D001161:Arteriosclerosis / Q000097:blood / Q000150:complications / Q000188:drug therapy; D001809:Blood Viscosity / Q000187:drug effects*; D002561:Cerebrovascular Disorders / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D004359:Drug Therapy, Combination; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000150:complications / Q000188:drug therapy; D008875:Middle Aged
Vliianie kompleksnogo medikamentoznogo lecheniia na reologicheskie svoĭstva krovi u bol'nykh distsirkuliatornoĭ éntsefalopatieĭ.