title: [Sterigmatocystin induced adenocarcinoma of the lung and atypical hyperplasia of glandular stomach in mice].
abstract: Aspergillus versicolor was isolated from the gastric juice of patients with chronic stomach diseases in high-risk area of gastric cancer. Mice fed with aspergillus-inoculated corn flour developed adenocarcinoma of the lung in 15 of 35 mice (42.9%) and atypical hyperplasia of the glandular stomach in 13 of 35 mice (37.4%). Sterigmatocystin was identified by HPLC and fluorescence spectrophotometry in the extract of aspergillus-inoculated corn flour. The results suggest that the mycotoxin sterigmatocystin is a potential carcinogen in human.
authors.affiliation: Hebei Medical College, Shijiazhuang.
authors.forename: T X
authors.initials: TX
authors.lastname: Xie
mesh_terms: D000230:Adenocarcinoma / Q000139:chemically induced*; D000818:Animals; D005260:Female; D006965:Hyperplasia; D008175:Lung Neoplasms / Q000139:chemically induced*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D011230:Precancerous Conditions / Q000139:chemically induced; D013241:Sterigmatocystin; D013270:Stomach / Q000473:pathology*
chemical_list: D013241:Sterigmatocystin