[Synthesis and animal experiments of ethylnitrosourea].
Ethylnitrosourea (ENU) was synthesized with raw materials such as ethylamine and sodium nitrite. The product was a yellowish powder. Its melting point, solubility and infrared absorption spectrum coincided with those reported in the literature. The result form elementary analysis for the product was almost the same as the theoretical value. The product was applied to rats by various methods. It was found that ENU was a cancerogenic compound, especially to the nervous system. More details about the animal experiments will be published in some other papers.
Tao
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Yang
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Huang
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D000818:Animals; D001932:Brain Neoplasms / Q000139:chemically induced; D003390:Cranial Nerve Neoplasms / Q000139:chemically induced; D005038:Ethylnitrosourea / Q000138:chemical synthesis*; D005260:Female; D005910:Glioma / Q000139:chemically induced; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D014276:Trigeminal Nerve
D005038:Ethylnitrosourea