[Rapid diagnosis of epidemic cerebrospinal meningitis by co-agglutination].
Group A meningococcus polysaccharide antigen from cerebrospinal fluid (CSF), serum and urine were detected by Co-agglutination (COA) method. In total 478 samples, CSF, sear and urines 195, 214, and 69 samples were detected respectively. COA positive rate of CSF were 81.2%, serum were 64.6% and urine were 50%, in the patients from whom group A bacteria were isolated, but the samples from which group B meningococcus, pneumococcus or other isolates positive showed negative in COA. A good sensitivity and specificity of COA method have been proved in this paper. The advantages of COA method were rapid, simple and could be easily performed in ordinary laboratory conditions.
Gao
E M
EM
National Institute for the control of Pharmaceutical and Biological Products, Beijing.
D000372:Agglutination Tests / Q000379:methods; D000942:Antigens, Bacterial / Q000032:analysis; D006801:Humans; D008585:Meningitis, Meningococcal / Q000175:diagnosis*; D011135:Polysaccharides, Bacterial / Q000276:immunology; D013205:Staphylococcal Protein A / Q000276:immunology
D000942:Antigens, Bacterial; D011135:Polysaccharides, Bacterial; D013205:Staphylococcal Protein A; C043226:meningococcal group A polysaccharide