title: Hypertension in sickle cell disease.
abstract: We report a young male with sickle cell trait who developed severe hypertension and splenic infarction soon after travel to a high altitude. Hypertension persisted for three days after a diagnostic laparotomy. His blood pressure then continued to be normal over the next one and a half years. Red cell sludging in the small vessels of the kidney possibly activated the renin angiotensin system.
authors.affiliation: Department of Medicine Unit-I, CMC Hospital, Vellore, Tamil Nadu.
authors.forename: C
authors.initials: C
authors.lastname: Narasimhan
authors.forename: T
authors.initials: T
authors.lastname: George
authors.forename: J T
authors.initials: JT
authors.lastname: George
authors.forename: B M
authors.initials: BM
authors.lastname: Pulimood
mesh_terms: D000328:Adult; D000532:Altitude Sickness / Q000209:etiology; D000755:Anemia, Sickle Cell / Q000150:complications*; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D008297:Male; D012805:Sickle Cell Trait / Q000150:complications*; D013159:Splenic Infarction / Q000209:etiology*