title: Extensive nuclear lobulation in the cells of a patient with acute myelomonocytic leukemia. The role of electron microscopy for establishment of a correct diagnosis.
abstract: Extensive nuclear convolution and lobulation was found in the peripheral blood cells of a patient with acute leukemia. While the morphology of the cells, such as observed with the light microscope, was compatible with the diagnosis of acute myeloid leukemia, the finding of Sezary-like cells with the electron microscope helped to establish the diagnosis of acute myelomonocytic leukemia. This report emphasizes the importance of the electron microscope for the correct diagnosis of leukemias.
authors.affiliation: Department of Medicine B, Hasharon Hospital, Petah-Tiqva, Israel.
authors.forename: M
authors.initials: M
authors.lastname: Djaldetti
authors.forename: A
authors.initials: A
authors.lastname: Cohen
authors.forename: J
authors.initials: J
authors.lastname: Gardyn
authors.forename: D
authors.initials: D
authors.lastname: Bendayan
mesh_terms: D000368:Aged; D001853:Bone Marrow / Q000473:pathology / Q000648:ultrastructure*; D006801:Humans; D015479:Leukemia, Myelomonocytic, Acute / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D008854:Microscopy, Electron