title: Midfacial necrotizing lesion of the nasal cavity attributable to peripheral T-cell lymphoma.
abstract: The initial progression of a nonhealing ulcerative lesion in the nasopalatal region with nondiagnostic biopsy results, combined with progression of systemic symptoms, is suggestive of a PTL. Because therapy requires accurate histologic diagnosis, the clinician must be persistent to make a correct diagnosis. As the disease progresses, PTL histology matures, allowing diagnosis with immunohistochemical techniques. It is possible that earlier diagnosis will allow more timely treatment and a reduction in mortality related to this disease.
authors.affiliation: Department of Otolaryngology--Head and Neck Surgery, University of Southern California, Los Angeles County Medical Center.
authors.forename: J R
authors.initials: JR
authors.lastname: Austin
authors.forename: M C
authors.initials: MC
authors.lastname: Fieber
mesh_terms: D001706:Biopsy; D006801:Humans; D007150:Immunohistochemistry; D008223:Lymphoma / Q000175:diagnosis / Q000473:pathology* / Q000503:physiopathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity / Q000473:pathology* / Q000503:physiopathology; D009300:Nasal Septum / Q000473:pathology; D009336:Necrosis / Q000473:pathology; D013601:T-Lymphocytes