title: A comparison of the effects of alfentanil/droperidol or fentanyl/droperidol on intra-ocular pressure.
abstract: The influence of two intravenous sedative regimens on intra-ocular pressure was investigated in conjunction with retrobulbar local anaesthesia. Forty patients were allocated randomly to either group A (alfentanil and droperidol) or group F (fentanyl and droperidol). Measurements of intra-ocular pressure, arterial pressure and oxygen saturation were made before operation, after premedication, after intravenous sedation and after surgery. Paco2 was also measured before and after operation. Each sedation technique caused a similar reduction in intra-ocular pressure. There was less effect on Paco2 and oxygenation in group A.
authors.affiliation: Department of Anaesthesia, Leicester Royal Infirmary.
authors.forename: S
authors.initials: S
authors.lastname: Coley
authors.forename: G W
authors.initials: GW
authors.lastname: Jones
authors.forename: D
authors.initials: D
authors.lastname: Lassey
authors.forename: A E
authors.initials: AE
authors.lastname: May
authors.forename: D
authors.initials: D
authors.lastname: Fell
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015760:Alfentanil / Q000494:pharmacology*; D000772:Anesthesia, Local; D001794:Blood Pressure / Q000187:drug effects; D002387:Cataract Extraction; D004329:Droperidol / Q000494:pharmacology*; D005123:Eye / Q000294:innervation; D005260:Female; D005283:Fentanyl / Q000494:pharmacology*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D009407:Nerve Block; D010100:Oxygen / Q000097:blood; D011229:Preanesthetic Medication; D011897:Random Allocation
chemical_list: D015760:Alfentanil; D004329:Droperidol; D010100:Oxygen; D005283:Fentanyl