Fibrillary glomerulonephritis in a patient with metastatic carcinoma of the liver.
A 61-year-old women presented with nephrotic syndrome and progressive renal failure associated with metastatic adenocarcinoma of the liver. Renal biopsy revealed marked widening of the basement membrane and nonamyloidotic fibrillary deposits composed chiefly of polyclonal IgG. This is the first reported case of Congo-red-negative fibrillary glomerulopathy in association with adenocarcinoma of the liver.
Abraham
G
G
Division of Nephrology, Toronto Western Hospital, Ont., Canada.
Bargman
J M
JM
Blake
P G
PG
Katz
A
A
Oreopoulos
D G
DG
D000230:Adenocarcinoma / Q000150:complications / Q000556:secondary*; D001859:Bone Neoplasms / Q000150:complications / Q000556:secondary; D005260:Female; D005921:Glomerulonephritis / Q000150:complications* / Q000473:pathology; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007668:Kidney / Q000473:pathology*; D007676:Kidney Failure, Chronic / Q000209:etiology; D008113:Liver Neoplasms / Q000150:complications*; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000209:etiology
D007074:Immunoglobulin G