title: Acute oxalate poisoning attributable to ingestion of curly dock (Rumex crispus) in sheep.
abstract: Ten of 100 mature ewes were afflicted with acute oxalate toxicosis within 40 hours after being temporarily penned in a lot that contained considerable growing Rumex crispus (curly dock). Clinical signs of toxicosis included excess salivation, tremors, ataxia, and recumbency. Affected ewes were markedly hypocalcemic and azotemic. Oxalate crystals were not observed in urine. Gross postmortem lesions were minimal and nondiagnostic in 2 ewes that died peracutely, but perirenal edema and renal tubular degeneration were clearly observable in ewes euthanatized on the third day of toxicosis. Diagnosis of oxalate toxicosis was confirmed by histopathologic findings. Samples of Rumex spp contained 6.6 to 11.1% oxalic acid on a dry-weight basis, a concentration comparable with that in other oxalate-containing plants that have caused acute oxalate toxicosis.
authors.affiliation: Department of Veterinary Pathology, College of Veterinary Medicine, Oklahoma State University, Stillwater 74078.
authors.forename: R J
authors.initials: RJ
authors.lastname: Panciera
authors.forename: T
authors.initials: T
authors.lastname: Martin
authors.forename: G E
authors.initials: GE
authors.lastname: Burrows
authors.forename: D S
authors.initials: DS
authors.lastname: Taylor
authors.forename: L E
authors.initials: LE
authors.lastname: Rice
mesh_terms: D058186:Acute Kidney Injury / Q000662:veterinary*; D000818:Animals; D005260:Female; D006996:Hypocalcemia / Q000139:chemically induced / Q000662:veterinary; D007668:Kidney / Q000473:pathology; D007683:Kidney Tubular Necrosis, Acute / Q000139:chemically induced / Q000662:veterinary*; D010070:Oxalates / Q000506:poisoning*; D010939:Plant Poisoning / Q000662:veterinary*; D012756:Sheep; D012757:Sheep Diseases / Q000139:chemically induced*; D014511:Uremia / Q000139:chemically induced / Q000662:veterinary
chemical_list: D010070:Oxalates