[Characteristics of immune reactions to the influenza virus in mice with a slow influenzal infection].
It had previously been shown that intrauterine infection of mice with influenza virus resulted in growth retardation and significant immunosuppression to various nonspecific agents and influenza virus. The present study demonstrated that such mice also had lower production of specific antibody and reduced capacity to form the delayed hypersensitivity to influenza virus. Despite the lack of specific immune response, such mice had high levels of response to influenza virus in adoptive transfer. The reasons for which lymphocytes of mice with slow influenza infection fail to manifest their immunological potentials in situ require further study.
Cherniakhovskaia
I Iu
IIu
Kobets
N V
NV
Mirchink
E P
EP
Fontalin
L N
LN
Zuev
V A
VA
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D000918:Antibody Specificity / Q000276:immunology; D000921:Antibody-Producing Cells / Q000276:immunology; D000937:Antigen-Antibody Reactions / Q000276:immunology*; D005260:Female; D006968:Hypersensitivity, Delayed / Q000276:immunology; D009980:Influenza A virus / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D009976:Orthomyxoviridae Infections / Q000276:immunology*; D011247:Pregnancy; D012897:Slow Virus Diseases / Q000276:immunology*
D000914:Antibodies, Viral
Osobennosti immunnykh reaktsiĭ na virus grippa u mysheĭ pri medlennoĭ grippoznoĭ infektsii.