Bilateral spontaneous dislocated lenses, retinal vasculitis and progeria-like changes.
Findings are reported for a 70-year-old man with a progeria-like syndrome consisting of premature aging (per history), diffuse wasting, skin atrophy, disseminated skeletal osteoporosis (documented for at least 25 years), especially in the vertebral column and metacarpal joints with short stature, beaked nose and high-pitched voice, The ocular findings include: spontaneous bilateral dislocation of spherophakic mature cataracts into the vitreous together with bilateral retinal vasculitis, characterized by venous congestion, tortuosity and occlusion, To the best of our knowledge, there is no case report with all the above features in one person, Hence, the differential diagnosis will also be discussed.
Sharir
M
M
Goldschlager Eye Institute, Sheba Medical Center, Tel Hashomer, Israel.
Ragenbogen
L
L
D000368:Aged; D002386:Cataract / Q000150:complications / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D007906:Lens Subluxation / Q000150:complications / Q000473:pathology*; D008297:Male; D012164:Retinal Diseases / Q000150:complications / Q000473:pathology*; D014657:Vasculitis / Q000150:complications / Q000473:pathology*; D014898:Werner Syndrome / Q000150:complications / Q000473:pathology*