title: Decreased necessity for dialysis with loop diuretic therapy in hemolytic uremic syndrome.
abstract: High dose loop diuretic therapy was administered at time of admission to hospital or at time of diagnosis to 54 patients with childhood hemolytic uremic syndrome. Forty-one patients maintained a diuresis sufficient to avoid the necessity for dialysis. When compared to an earlier time period the dialysis rate fell from 82% to 24% with furosemide therapy. Though a change in disease severity may explain the decrease in necessity for dialysis, a salutary effect of furosemide therapy may also be responsible.
authors.affiliation: Department of Pediatrics, University of Montreal, Hôpital Ste-Justine, Quebec, Canada.
authors.forename: E
authors.initials: E
authors.lastname: Rousseau
authors.forename: N
authors.initials: N
authors.lastname: Blais
authors.forename: S
authors.initials: S
authors.lastname: O'Regan
mesh_terms: D001806:Blood Urea Nitrogen; D002675:Child, Preschool; D003404:Creatinine / Q000378:metabolism; D005665:Furosemide / Q000627:therapeutic use*; D006454:Hemoglobins; D006463:Hemolytic-Uremic Syndrome / Q000188:drug therapy* / Q000628:therapy; D006801:Humans; D007262:Infusions, Intravenous; D010530:Peritoneal Dialysis; D010976:Platelet Count; D012189:Retrospective Studies
chemical_list: D006454:Hemoglobins; D005665:Furosemide; D003404:Creatinine