Sister chromatid exchanges induced in peripheral lymphocytes of workers exposed to low concentrations of styrene.
This study employed a longitudinal sampling design to obtain measurements of exposure and exhaled air from all members of a cohort several times over the course of one year. Styrene in exhaled air correlated well with styrene in breathing zone air. Both smoking and exposure to styrene appear to have contributed significantly and separately to increased SCEs. Early results imply that SCEs were somewhat more highly correlated with styrene in exhaled air than in breathing zone air.
Yager
J W
JW
Department of Biomedical and Environmental Health Sciences, University of California, Berkeley 94720.
Paradisin
W M
WM
Symanski
E
E
Rappaport
S M
SM
D000328:Adult; D000395:Air Pollutants, Occupational / Q000633:toxicity; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D012854:Sister Chromatid Exchange / Q000187:drug effects*; D012907:Smoking / Q000235:genetics; D020058:Styrene; D013343:Styrenes / Q000633:toxicity*
D000395:Air Pollutants, Occupational; D013343:Styrenes; D020058:Styrene