[Urinary calculus protective side effects of anti-rheumatic therapy].
In a retrospective study two patient groups suffering from recurrent calcium oxalate lithiasis are compared before and after antirheumatic therapy using Diclofenac-Natrium alone or in combination with xanthine oxidase inhibitors and/or hydrochlorothiazides. The examination of concentration and excretion of lithogenic important parameters show a partly significant reduction of the concentration mean values of calcium, oxalic acid and uric acid. The influence of non-steroidal antiphlogistics (NSAP) on calculus recurrence rate in calcium oxalate lithiasis is recognized.
Schlichter
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Urologische Klinik und Poliklinik, Bereichs Medizin der Friedrich-Schiller-Universität Jena.
Brundig
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P
D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000652:urine; D002118:Calcium / Q000652:urine; D002129:Calcium Oxalate / Q000652:urine*; D004008:Diclofenac / Q000008:administration & dosage*; D005500:Follow-Up Studies; D006801:Humans; D007213:Indomethacin / Q000008:administration & dosage*; D008274:Magnesium / Q000652:urine; D014527:Uric Acid / Q000652:urine; D014545:Urinary Calculi / Q000517:prevention & control* / Q000652:urine
D004008:Diclofenac; D002129:Calcium Oxalate; D014527:Uric Acid; D008274:Magnesium; D002118:Calcium; D007213:Indomethacin
Harnsteinprotektive Nebeneffekte bei antirheumatischer Therapie.