title: Extramedullary plasmacytoma of the thyroid associated with a serum monoclonal gammopathy.
abstract: Extramedullary plasmacytoma is a malignant plasma cell dyscrasia that is most commonly found in the head and neck. Progression to disseminated disease in the form of multiple myeloma occurs in 17% to 32% of cases. Herein, we describe a patient with extramedullary plasmacytoma of the thyroid gland in whom a serum monoclonal gammopathy resolved with surgery and irradiation of the primary. Although rare, this diagnosis should be considered in patients presenting with obstructive thyromegaly and autoimmune thyroiditis.
authors.affiliation: Department of Otolaryngology, University of Pittsburgh School of Medicine, PA.
authors.forename: J
authors.initials: J
authors.lastname: Rubin
authors.forename: J T
authors.initials: JT
authors.lastname: Johnson
authors.forename: R
authors.initials: R
authors.lastname: Killeen
authors.forename: L
authors.initials: L
authors.lastname: Barnes
mesh_terms: D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D010265:Paraproteinemias / Q000209:etiology*; D010954:Plasmacytoma / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D013964:Thyroid Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000628:therapy