title: [Treatment of retinoblastoma and results. Lausanne 1963-1989].
abstract: 97 cases of retinoblastoma were studied with particular attention to methods of treatment and results. The series includes 41 unilateral cases (42%) and 56 bilateral cases (58%), giving a total of 153 eyes. Of these, 19 (20%) were familial cases. Immediate enucleation was necessary in 88 of the 153 eyes; 61 eyes received conservative treatment; 4 eyes, including one bilateral case, showed spontaneous recovery (retinomas). Conservative treatment consisted of high-voltage external beam irradiation in 43 cases, cryo or photocoagulation in 12 cases, and radioactive applicators in 6 cases. The mortality-rate in cases with over 2-years follow up is of 11%. In 65% of treated cases the eye was saved, with 87% of these retaining useful or central vision. The most serious complications are radiation retinopathy (19%), cataract (16%) and exsudative retinal detachment (9%).
authors.affiliation: Clinique ophtalmologique universitaire de Lausanne.
authors.forename: A
authors.initials: A
authors.lastname: Balmer
authors.forename: C
authors.initials: C
authors.lastname: Gailloud
authors.forename: P
authors.initials: P
authors.lastname: De Potter
authors.forename: F
authors.initials: F
authors.lastname: Munier
authors.forename: J
authors.initials: J
authors.lastname: Chamero
mesh_terms: D001918:Brachytherapy / Q000379:methods; D002648:Child; D003131:Combined Modality Therapy; D003452:Cryosurgery; D015353:Eye Enucleation; D005134:Eye Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy; D009378:Neoplasms, Multiple Primary / Q000532:radiotherapy* / Q000601:surgery; D012175:Retinoblastoma / Q000532:radiotherapy* / Q000601:surgery
vernacular_title: Traitement du rétinoblastome et résultats. Lausanne 1963-1989.