title: Predicting the compliance of small diameter vascular grafts from uniaxial tensile tests.
abstract: The compliance hypothesis states that the compliance of vascular grafts should match that of the host artery for optimal patency. Although this has not been proven, the literature shows that much effort has gone into measuring compliance. Uniaxial circumferential tensile tests are simpler than compliance tests, but do not give the compliance (a multiaxial property) directly. Therefore, we have used mechanical models to correlate the two. Simple models suffer from inappropriate simplifying assumptions. In a clinically useful range, a Laplace law model and an incremental elasticity model do not predict the compliance from the rigidity as well as does a model derived from finite elasticity. This latter model has helped locate sources of errors. Variations in graft thickness, diameter, and anisotropy may be responsible for scatter in the experimental correlations between compliance and uniaxial rigidity.
authors.affiliation: Department of Materials Science and Engineering, University of Utah, Salt Lake City 84112.
authors.forename: S F
authors.initials: SF
authors.lastname: Stewart
authors.forename: D J
authors.initials: DJ
authors.lastname: Lyman
mesh_terms: D000818:Animals; D001158:Arteries / Q000502:physiology / Q000637:transplantation*; D001807:Blood Vessel Prosthesis; D003187:Compliance; D004285:Dogs; D006801:Humans; D008955:Models, Cardiovascular; D013314:Stress, Mechanical; D013718:Tensile Strength / Q000502:physiology; D014654:Vascular Patency / Q000502:physiology