[Nuclear DNA content in tumors of the colon and rectum. Relationship between ploidy and site of the neoplasm].
The DNA distribution pattern was determined 30 colo-rectal carcinomas. The DNA content in individual cells was measured according to a cytophotometric method based on light transmission measurement of Feulgen-stained nuclei. The DNA non diploid carcinomas were significantly more common from the left (descending and sigmoid) colon and rectum (P = 0.0002). No relationship existed between DNA pattern and age, sex, Dukes' stage, tumor grade.
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GC
Cattedra di Patologia Speciale Chirurgica II, Università degli Studi di Genova.
Ottonello
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M
Testa
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T
Scarpettini
S
S
Abbondati
A
A
Capponi
G
G
D000230:Adenocarcinoma / Q000235:genetics*; D000328:Adult; D000368:Aged; D003110:Colonic Neoplasms / Q000235:genetics*; D004273:DNA, Neoplasm / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011003:Ploidies; D012004:Rectal Neoplasms / Q000235:genetics*
D004273:DNA, Neoplasm
Contenuto nucleare di DNA nei tumori del colon-retto. Rapporto tra ploidia e sede della neoplasia.