title: Disseminated skeletal lesions associated with pathogenic actinomycetes in a Pygmy hog (Sus salvanius).
abstract: The clinical and pathological features of an unusual crippling bone disease in an adult male Pygmy Hog, Sus salvanius, born the smallest in a litter of five and representing the rarest of the known living Suidae, are described. Radiological studies revealed severe spondylosis deformans and focal sharply demarcated radiolucencies in virtually the whole skeleton, but particularly in the bones of the skull, the processes of multiple vertebrae, the ribs, scapulae and parts of the humeri and femora. The clinical chemistry measurements were indicative of pathological lytic processes in the skeleton. The focal bone lesions consisted of caseous necrosis, dystrophic calcification and peripheral fibroblastic demarcation. They contained colonies of filamentous bacteria identified as members of the Order Actinomycetales. Case history evidence suggests that the infection may have resulted from repeated skin trauma inflicted by litter-mates.
authors.affiliation: Department of Preclinical Veterinary Sciences, University of Edinburgh, Scotland.
authors.forename: A A
authors.initials: AA
authors.lastname: Macdonald
authors.forename: P
authors.initials: P
authors.lastname: Ossent
authors.forename: A
authors.initials: A
authors.lastname: Rubel
authors.forename: B
authors.initials: B
authors.lastname: Hauser
authors.forename: E
authors.initials: E
authors.lastname: Isenbugel
authors.forename: C R
authors.initials: CR
authors.lastname: Schmidt
mesh_terms: D000193:Actinomycetales Infections / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D001847:Bone Diseases / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D006614:Hindlimb; D008159:Lumbar Vertebrae; D008297:Male; D009135:Muscular Diseases / Q000473:pathology / Q000662:veterinary*; D011859:Radiography; D013128:Spinal Osteophytosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000473:pathology*; D013556:Swine, Miniature; D013904:Thoracic Vertebrae