title: Treatment of transitional cell carcinoma of the ureter: is the controversy justified?
abstract: Between 1938 and 1985, 73 patients with ureteral tumors underwent surgery at Puigvert Foundation (1 case with bilateral synchronous tumors). Sixty-three patients were males and 10 females. Ages ranged between 49 and 78 (mean of 62) years. Tumoral stages were: pTa 5 cases; pT1 56 cases; pT2 10 cases, and pT3 2 cases. Radical treatment was performed in 38 cases and conservative treatment in 35 cases. Follow-up ranged between 2 and 20 (mean of 7) years. The overall survival rate at 5 years was 100, 82 and 50% for stages pTa, pT1 and pT2-3, respectively (p less than 0.05). Analyzed together, the actuarial survival at 5 years was 90.3% with conservative surgery and 67.8% with radical surgery (p not significant). The survival by stages for the patients treated with radical surgery was: 100% in pTa; 69.6% in pT1, and 57.1% in pT2-3. For those treated conservatively, survival was 100% in pTa, 95.8% in pT1 and 33.3% in pT2. Thus patients presenting with infiltrating tumors should not be treated conservatively, while patients with superficial lesions had a similar evolution whether treated by conservative or radical surgery.
authors.affiliation: Urology Service, Puigvert Foundation, Barcelona, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Zungri
authors.forename: G
authors.initials: G
authors.lastname: Chéchile
authors.forename: F
authors.initials: F
authors.lastname: Algaba
authors.forename: I
authors.initials: I
authors.lastname: Diaz
authors.forename: F
authors.initials: F
authors.lastname: Vilá
authors.forename: C
authors.initials: C
authors.lastname: Castro
mesh_terms: D002295:Carcinoma, Transitional Cell / Q000401:mortality / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D015996:Survival Rate; D013997:Time Factors; D014513:Ureter / Q000601:surgery; D014516:Ureteral Neoplasms / Q000401:mortality / Q000601:surgery*; D014547:Urinary Diversion