title: [Functional classification of pituitary adenomas].
abstract: Pituitary adenomas might be classified into different groups according to different variety of hormone produced. 225 surgical specimens were labeled with anti- sera of GH, PRL, ACTH, TSH, FSH, and LH, via immunohistochemical technique (ABC method). Data indicated that 100 out of the 225 (44.5%) were monohormonal adenomas, including 24 GH, 39 PRL, 1 FSH and 9 LH, 77 (34.2%) were multi- hormonal adenomas, including 28 positive for 2 hormones, 30 positive for 3 hormones, 19 positive for 4 or more different hormones, and the remaining 48 (21.3%) were nonfunctional adenomas. In comparison with Kovacs series, factors which might participate in the mechanism of developing monohormonal or multi- hormonal adenomas are discussed.
authors.affiliation: Institute of Neurology, Huashan Hospital of Shanghai Medical University.
authors.forename: F L
authors.initials: FL
authors.lastname: Zhang
mesh_terms: D000236:Adenoma / Q000145:classification* / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D010907:Pituitary Hormones / Q000378:metabolism; D010911:Pituitary Neoplasms / Q000145:classification* / Q000378:metabolism
chemical_list: D010907:Pituitary Hormones