[Immunosorption in the treatment of bronchial asthma patients. The late results of a 5-year observation].
Analysis was made of the long-term results of immunosorption in 30 patients afflicted with bronchial asthma. 26 patients (14 with hypersensitivity to home dust allergen and 12 with pollenosis associated with hypersensitivity to timothy pollen allergen) received extracorporeal immunosorption: 1 patient underwent extracorporeal lymphocytic perfusion, 3 patients extracorporeal anti-IgE-plasma immunosorption. The use of immunosorption provides short-term beneficial results. The follow-up for 1 to 5 years revealed that the procedure exerted a beneficial action in 24 patients. In 6 patients, immunosorption did not produce any noticeable effect or else it was short-lived. External respiratory function differed substantially before and after immunosorption and correlated with the clinical improvement of the patients' status. Examination of cellular humoral immunity permitted the positive dynamics to be established in the content of T-lymphocyte subpopulations, the total and specific IgE.
Chuchalin
A G
AG
Raudla
L A
LA
D000293:Adolescent; D000328:Adult; D000936:Antigen-Antibody Complex / Q000627:therapeutic use*; D001249:Asthma / Q000276:immunology / Q000628:therapy*; D005112:Extracorporeal Circulation / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007164:Immunosorbents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012119:Respiration; D012130:Respiratory Hypersensitivity / Q000276:immunology / Q000628:therapy; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology / Q000628:therapy
D000936:Antigen-Antibody Complex; D007164:Immunosorbents; D007073:Immunoglobulin E
Immunosorbtsiia v lechenii bol'nykh bronkhial'noĭ astmoĭ. Otdalennye rezul'taty 5-letnego nabliudeniia.