Late results of combined iodine-125 and external beam radiotherapy in carcinoma of prostate.
A total of 96 patients were treated for localized carcinoma of the prostate using combined Iodine-125 (125I) implantation and external beam radiotherapy. The implant was tailored to deliver 10,000 rad to the periphery of the prostate. A significant incidence of serious late rectal complications was observed. Positive pelvic nodes were found in 28 percent of the patients. Disease-free survival at seven years was 76 percent for those with negative nodes and 46 percent for patients with positive nodes.
Patel
J
J
Division of Urology, University of Missouri School of Medicine, Columbia.
Worthen
R
R
Abadir
R
R
Weaver
D J
DJ
Weinstein
S
S
Ross
G
G
D005402:Fistula / Q000209:etiology; D005500:Follow-Up Studies; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D008207:Lymphatic Metastasis; D008297:Male; D009367:Neoplasm Staging; D011349:Proctitis / Q000209:etiology; D011469:Prostatic Diseases / Q000209:etiology; D011471:Prostatic Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D011832:Radiation Injuries; D011878:Radiotherapy / Q000379:methods; D012003:Rectal Fistula / Q000209:etiology; D012008:Recurrence; D015996:Survival Rate; D014549:Urinary Incontinence / Q000209:etiology
D007457:Iodine Radioisotopes