title: [Trypsin and pancreatic elastase-inhibitory capacity of serum and bronchoalveolar lavage fluid of smokers, ex-smokers and nonsmokers].
abstract: Smoking habits have no differentiating effect on the functional activity of protease inhibitor (alpha 1PI) in the serum and bronchoalveolar lavage fluid (BALF). In the BALF, the trypsin-inhibitory capacity TIC/alpha 1PI ratio is significantly greater in patients with emphysema than in non-emphysematous subjects. PIC/alpha 1PI ratios that are greater than 1 demonstrate the existence of additional antiproteases in the lower respiratory tract.
authors.affiliation: Thoraxklinik Heidelberg-Rohrbach.
authors.forename: W
authors.initials: W
authors.lastname: Ebert
authors.forename: G
authors.initials: G
authors.lastname: Trefz
authors.forename: B
authors.initials: B
authors.lastname: Heck
authors.forename: V
authors.initials: V
authors.lastname: Schulz
mesh_terms: D001992:Bronchoalveolar Lavage Fluid / Q000032:analysis*; D006801:Humans; D010196:Pancreatic Elastase / Q000037:antagonists & inhibitors*; D011656:Pulmonary Emphysema / Q000201:enzymology*; D012907:Smoking / Q000097:blood*; D014361:Trypsin Inhibitors / Q000097:blood*; D000515:alpha 1-Antitrypsin / Q000378:metabolism*
chemical_list: D014361:Trypsin Inhibitors; D000515:alpha 1-Antitrypsin; D010196:Pancreatic Elastase
vernacular_title: Trypsin- und Pankreaselastase-inhibitorische Kapazität von Serum und bronchoalveolärer Lavageflüssigkeit bei Rauchern, Exrauchern und Nichtrauchern.