Skeletal muscle pathology in AIDS: an autopsy study.
A survey of skeletal muscle pathology in 92 autopsied cases of AIDS revealed microscopic alterations in 64 cases. There were 40 cases of disuse atrophy, 8 of denervation atrophy, 2 of cryptococcal myositis, 1 of Mycobacterium avium intracellulare (MAI) infection and 2 of necrotizing myopathy associated with hyperkalemia. A second group of cases with changes of unknown etiology was found. These were tentatively ascribed to the direct or indirect action of HIV. This category includes 8 cases of inflammatory myopathy, 8 of necrotizing myopathy in absence of a known etiological factor, 3 of extreme atrophy and 4 of "regenerating" myopathy.
Wrzolek
M A
MA
State University of New York Health Science Center, Brooklyn and Kings County Hospital Center.
Sher
J H
JH
Kozlowski
P B
PB
Rao
C
C
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000453:epidemiology / Q000473:pathology*; D001706:Biopsy; D005260:Female; D006801:Humans; D008297:Male; D009132:Muscles / Q000473:pathology*; D009135:Muscular Diseases / Q000150:complications / Q000453:epidemiology / Q000473:pathology*