title: [Thymolytic effects of methandrostenolone].
abstract: It was shown, that in castrated rats dianabol (10 mg/kg of body mass daily for 7 days) inhibits the protein synthesis in thymus. The binding analysis of 3H-dianabol showed the specific binding sites in thymic cytosol, which are identical to those for androgens. Isolated thymocytes didn't bind dianabol.
authors.forename: N S
authors.initials: NS
authors.lastname: Chermnykh
authors.forename: A S
authors.initials: AS
authors.lastname: Dukhanin
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Andreev
authors.forename: Ch T
authors.initials: ChT
authors.lastname: Karymshakova
mesh_terms: D000728:Androgens / Q000378:metabolism; D000818:Animals; D001665:Binding Sites; D002369:Castration; D003600:Cytosol / Q000378:metabolism; D008297:Male; D008696:Methandrostenolone / Q000008:administration & dosage / Q000494:pharmacology*; D014176:Protein Biosynthesis; D051381:Rats; D013601:T-Lymphocytes / Q000378:metabolism; D013950:Thymus Gland / Q000187:drug effects* / Q000378:metabolism; D013997:Time Factors
chemical_list: D000728:Androgens; D008696:Methandrostenolone
vernacular_title: Izuchenie mekhanizmov timoliticheskogo éffekta metandrostenolona.