title: [Efficacy of intra-arterial infusion chemotherapy in colorectal cancer with liver metastasis].
abstract: Twenty-nine cases with metastatic liver cancer from colorectal carcinoma were reviewed to clarify the efficacy of intra-arterial infusion chemotherapy for survival. Liver resection was performed in eight cases, ten patients were treated with intra-arterial chemotherapy and 11 patients by systemic chemotherapy. The survival rate was calculated by Kaplan-Meier method. One-year and two-year survival rate were 65% and 65% in the resected group, 63% and 32% in the intra-arterial chemotherapy group, and 45% and 0% in the systemic chemotherapy group. More favorable results were observed in the intra-arterial chemotherapy group than the systemic group, especially in H2 patients. However, no statistical difference was observed. From our results, intra-arterial chemotherapy may be an effective treatment for the patients with liver metastasis from colorectal cancer in terms of survival.
authors.affiliation: Dept. of Surgery, Sendai National Hospital.
authors.forename: K
authors.initials: K
authors.lastname: Kakizaki
authors.forename: N
authors.initials: N
authors.lastname: Takahashi
authors.forename: H
authors.initials: H
authors.lastname: Yamauchi
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D015179:Colorectal Neoplasms / Q000473:pathology; D003131:Combined Modality Therapy; D006498:Hepatectomy; D006801:Humans; D015918:Infusion Pumps, Implantable; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000556:secondary* / Q000601:surgery; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate