title: [The anti-arrhythmia properties of bonnecor metabolites].
abstract: The experiments on the model of aconitine-induced arrhythmia in anesthetized rats and awake dogs with cardiac rhythm disorders caused by the coronary artery occlusion showed that all four metabolites of bonnecor possessed the antiarrhythmic activity. Metabolite 4 proved to be the most active on both models of cardiac rhythm disorders.
authors.forename: E K
authors.initials: EK
authors.lastname: Grigor'eva
authors.forename: H
authors.initials: H
authors.lastname: Poppe
authors.forename: E A
authors.initials: EA
authors.lastname: Tolmacheva
authors.forename: L M
authors.initials: LM
authors.lastname: Krasnykh
mesh_terms: D000157:Aconitine; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000378:metabolism / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000188:drug therapy / Q000209:etiology; D003984:Dibenzazepines / Q000378:metabolism / Q000627:therapeutic use*; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D051381:Rats; D013997:Time Factors
chemical_list: D000889:Anti-Arrhythmia Agents; D003984:Dibenzazepines; C048166:tiracizine; D000157:Aconitine
vernacular_title: Antiaritmicheskie svoĭstva metabolitov bonnekora.