title: [Long-term results of high-tolerance extracorporeal methods in the light of the new high-efficiency treatments].
abstract: While the efficiency of treatment has been recently related to long-term clinical outcome, the relevance of tolerance on this subject, even on critically ill patients, has seldom been evaluated, for the limited size of single pools on high tolerance dialytic treatments (HTT) and the flux of pts. among treatments. Since 1981, on 2243 pts on files of the Dialytic Piedmont Regional Registry, 1399 treatments on acetate-hemodialysis (HD), 1153 on bicarbonate dialysis (BC) and 249 hemofiltration (HF) were compared by survival analysis (Mantel test) and yearly hospitalization rate (YH), according to age, factors of clinical high risk (HR) and presence of diabetes. BC and HF showed on HR pts. LTS comparable to HD (at 1 yr. 82, 78.3 vs 76.77%) despite the higher age, and the lower proportion of first choice (38.9%, 25% vs. 83.5%) testifying successful treatment of more critical cases. On non HR pts. HF, a less efficient treatment vs BD and AD, showed slightly reduced LTS (95.2% at 1 yr. vs. 98.1 and 97.9%). HY results higher on HF vs. BD on non HR pts. (10.4 vs. 5.3 and 2.1%) but improves on HR pts. (10.7 vs. 12.5%) and is lower than BC on diabetics (8.3 vs. 14.5%) (p less than 0.01).
authors.affiliation: Ospedale Maggiore S. Giovanni Battista (Molinette), Torino, Cattedra di Nefrologia dell'Università.
authors.forename: A
authors.initials: A
authors.lastname: Pacitti
authors.forename: M
authors.initials: M
authors.lastname: Salomone
authors.forename: G P
authors.initials: GP
authors.lastname: Segoloni
authors.forename: A
authors.initials: A
authors.lastname: Vercellone
mesh_terms: D000328:Adult; D000368:Aged; D048909:Diabetes Complications; D005069:Evaluation Studies as Topic; D005260:Female; D015312:Hemodialysis Solutions; D006440:Hemofiltration; D006760:Hospitalization; D006801:Humans; D007558:Italy / Q000453:epidemiology; D007676:Kidney Failure, Chronic / Q000401:mortality / Q000628:therapy; D015993:Life Tables; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000379:methods*; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate
chemical_list: D015312:Hemodialysis Solutions
vernacular_title: Risultati a lungo termine delle metodiche extracorporee ad alta tolleranza alla luce dei nuovi trattamenti ad alta efficienza.