title: [Functional deficiency of riboflavin in patients with melanoma].
abstract: Preliminary data on the functional riboflavin deficiency in patients with malignant skin melanoma are discussed. In 50% of 36 patients with skin melanoma the glutathione reductase activation coefficient was higher than 1.21 and in 28% of the patients--above 1.31. Oral administration of high doses of riboflavin normalized the riboflavin status.
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Bukin
authors.forename: M Ia
authors.initials: MIa
authors.lastname: Kurtsman
authors.forename: A F
authors.initials: AF
authors.lastname: Mukeriia
authors.forename: D G
authors.initials: DG
authors.lastname: Zaridze
mesh_terms: D000328:Adult; D004789:Enzyme Activation; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D005980:Glutathione Reductase / Q000097:blood; D006801:Humans; D008297:Male; D008545:Melanoma / Q000097:blood* / Q000150:complications; D008875:Middle Aged; D012257:Riboflavin Deficiency / Q000097:blood* / Q000209:etiology
chemical_list: D005980:Glutathione Reductase
vernacular_title: Funktsional'naia nedostatochnost' riboflavina u bol'nykh melanomoĭ.