title: [Dose titration with Euphylong following prior determination of serum concentration in the steady state].
abstract: Euphylong is a theophylline preparation with new galenic slow-release design (micropellets in a capsule), developed for daily single-dose administration in the evening. It has been shown that the majority of patients with bronchial asthma, chronic obstructive bronchitis or emphysema who receive a single evening dose of Euphylong have a theophylline serum concentration that remains within the therapeutic range for 24 hours when the theophylline serum concentration measured at 8 a.m. under steady-state conditions is found to lie within the therapeutic range.
authors.affiliation: Abt. Pneumologie, Medizinische Universitätsklinik, Homburg/Saar.
authors.forename: D
authors.initials: D
authors.lastname: Schnabel
authors.forename: S
authors.initials: S
authors.lastname: von Treufels
authors.forename: M
authors.initials: M
authors.lastname: Oellerich
authors.forename: H C
authors.initials: HC
authors.lastname: Böttger
authors.forename: G W
authors.initials: GW
authors.lastname: Sybrecht
mesh_terms: D000328:Adult; D000368:Aged; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000097:blood / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D013806:Theophylline / Q000008:administration & dosage* / Q000493:pharmacokinetics
chemical_list: D013806:Theophylline
vernacular_title: Untersuchungen zur Dosistitration mit Euphylong nach vorausgegangener Serumkonzentrationsbestimmung im steady state.