Renal amyloidosis characterized by abnormally thick fibrils.
A renal biopsy of a 57-year-old man with nephrotic syndrome revealed marked glomerular deposition of Congo red-positive, bire-fringent material characteristic for amyloid. Ultrastructurally, however, this material is composed of nonbranching, haphazardly arranged fibrils of approximately three times the thickness of typical amyloid fibrils. To our knowledge, there has been no report of such a finding, and this unique case enlarges the morphologic spectrum of renal fibrillosis.
Yoshikawa
Y
Y
Department of Pathology, Baylor College of Medicine, Houston, TX.
Truong
L D
LD
Mattioli
C
C
Cartwright
J
J
D000686:Amyloidosis / Q000473:pathology*; D002648:Child; D003224:Congo Red; D006801:Humans; D007668:Kidney / Q000473:pathology*; D007674:Kidney Diseases / Q000473:pathology*; D008297:Male; D008854:Microscopy, Electron
D003224:Congo Red