title: Automated percutaneous lumbar discectomy with and without chymopapain pretreatment versus non-automated discoscopy-monitored percutaneous lumbar discectomy. An experimental study in human cadaver spines.
abstract: Percutaneous lumbar discectomy has gained growing interest during recent years as an alternative to open surgery for protrusions and non-sequestrated subligamentous intervertebral disc herniations. As a less invasive method it competes with chemonucleolysis. At least two modifications are known to date: automated percutaneous lumbar discectomy (APLD) with a 2-mm suction probe and non-automated, discoscopy-monitored percutaneous lumbar discectomy with a suction rongeur and a motor-driven shaver (NAPLD). In this study these two methods are compared for the amount of material extracted, dependence upon the degree of degeneration of the disc and intrinsic technical problems, using 20 human cadaver lumbar specimens for experimental testing. Total nucleotomy was not possible with either method. APLD yielded significantly less material and proved to be less effective in severely degenerated intervertebral discs than the NAPLD procedure, as preexisting gaps within the degenerated nucleus pulposus allowed the tissue to shift away from the tip of the 2-mm probe and facilitated displacement of the probe within the anulus fibrosus. By contrast, the rongeur, which first cuts the material to be removed and then carries it away by suction, was much more effective. Further data to support the advantages of non-automated percutaneous nucleotomy are discussed. Pretreatment of the disc with chymopapain did not result in a higher yield of nucleus material when combined with APLD.
authors.affiliation: Department of Orthopedic Surgery, University of Marburg/Lahn, Federal Republic of Germany.
authors.forename: M
authors.initials: M
authors.lastname: Pfeiffer
authors.forename: T
authors.initials: T
authors.lastname: Schäfer
authors.forename: P
authors.initials: P
authors.lastname: Griss
authors.forename: H D
authors.initials: HD
authors.lastname: Mennel
authors.forename: D
authors.initials: D
authors.lastname: Arndt
authors.forename: K
authors.initials: K
authors.lastname: Henkel
mesh_terms: D002917:Chymopapain / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004867:Equipment Design; D006801:Humans; D007403:Intervertebral Disc / Q000601:surgery*; D007404:Intervertebral Disc Chemolysis; D007405:Intervertebral Disc Displacement / Q000601:surgery / Q000628:therapy*; D008159:Lumbar Vertebrae / Q000601:surgery; D013396:Suction / Q000295:instrumentation; D013525:Surgical Instruments
chemical_list: D002917:Chymopapain