[Circulating immune complexes and myasthenia gravis (analysis of 78 cases)].
For the sake of studying the circulating immune complexes (CIC) of 78 patients with myasthenia gravis (MG), the agglutination assay of C3b sensitized with yeast cell (C3bSYCA) was used. The anti human C3 ELISA was also used for 21 out of the 78 patients. The positive results in the entire group of the patients studied were found to reach 82% and the IgG and IgM CIC were detected also with anti-human C3 ELISA. The titres of CIC thus determined decreased as the clinical conditions improved. It was considered that CIC might be regarded as a referential index to observe the patient's clinical condition and to evaluate the effect of treatment and to identify certain immune aberration of MG as well.
Tu
L H
LH
Changhai Hospital, Shanghai.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000372:Agglutination Tests / Q000379:methods; D000936:Antigen-Antibody Complex / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000276:immunology*
D000936:Antigen-Antibody Complex