title: Juxta-articular large cell lymphoma.
abstract: Three patients with juxta-articular large cell lymphoma presented as suffering from monarthropathies. A spectrum of radiographic changes was observed that included subchondral sclerosis, regional osteopenia, effusion, and mottled lytic changes in the juxta-articular region of the affected joint. MRI was performed in two patients. In one, it revealed a high signal mass on T2-weighted sequences. In the second, a mass bridging the joint was demonstrated which was difficult to appreciate on CT and was not visible radiographically. In all cases, biopsies revealed large cell non-Hodgkin's lymphoma of bone. We present these studies to emphasize this unusual pattern of non-Hodgkin's lymphoma as well as to demonstrate the contribution of MRI to the diagnosis.
authors.affiliation: Department of Diagnostic Radiology and Medical Imaging, Henry Ford Hospital, Detroit, Michigan 48202.
authors.forename: H V
authors.initials: HV
authors.lastname: Nghiem
authors.forename: B I
authors.initials: BI
authors.lastname: Ellis
authors.forename: A M
authors.initials: AM
authors.lastname: Haggar
authors.forename: J M
authors.initials: JM
authors.lastname: Meis
mesh_terms: D000173:Acromioclavicular Joint; D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis*; D004551:Elbow Joint; D005260:Female; D006801:Humans; D007592:Joint Diseases / Q000175:diagnosis*; D007719:Knee Joint; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed