title: Frequency and prognosis of arrhythmias after operative "correction" of tetralogy of Fallot.
abstract: Two hundred twenty-four consecutive patients operated on for tetralogy of Fallot were followed from 1 to 28 years (mean 11). Mean age at surgery was 5.3 years (range 1 to 14). Postoperative right ventricular systolic pressure was 60 mm Hg in 19 of 213 patients (9%). Fourteen patients (6%) had ventricular premature complexes on surface electrocardiograms. Seventy-nine patients underwent treadmill exercise tests, and ventricular premature complexes were induced in 17 (22%). Twenty-four-hour ambulatory monitoring in 92 patients demonstrated significant ventricular arrhythmias (greater than or equal to grade 2 of the Lown classification) in 41 (45%). The frequency of ventricular arrhythmias correlated with length of follow-up and duration of cardiopulmonary bypass. No correlation was found with age at surgery, postoperative right ventricular systolic pressure and importance of conduction defects on electrocardiogram. There were no sudden or unexpected deaths during follow-up.
authors.affiliation: Division of Pediatric Cardiology, Sainte-Justine Hospital, Montréal, Québec, Canada.
authors.forename: G
authors.initials: G
authors.lastname: Vaksmann
authors.forename: A
authors.initials: A
authors.lastname: Fournier
authors.forename: A
authors.initials: A
authors.lastname: Davignon
authors.forename: G
authors.initials: G
authors.lastname: Ducharme
authors.forename: L
authors.initials: L
authors.lastname: Houyel
authors.forename: J C
authors.initials: JC
authors.lastname: Fouron
mesh_terms: D000293:Adolescent; D001145:Arrhythmias, Cardiac / Q000188:drug therapy / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D015716:Electrocardiography, Ambulatory; D005080:Exercise Test; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D010672:Phenytoin / Q000627:therapeutic use; D011183:Postoperative Complications / Q000188:drug therapy; D011379:Prognosis; D012307:Risk Factors; D013771:Tetralogy of Fallot / Q000150:complications / Q000401:mortality / Q000601:surgery*
chemical_list: D010672:Phenytoin