title: On the hydrodynamic instability of hemoglobin solutions.
abstract: The formation of heterogeneous fibers well observable under a magnifying glass in stirred "stroma-free" hemolysates of outdated banked erythrocytes was found to be predominantly due to random surface denaturation of both hemoglobin and non-heme proteins at the air-liquid interface. Electrophoretic analysis revealed that the precipitated and washed fibers contain residual membrane proteins as well as a certain amount of hemoglobin. The latter, however, largely remains in solution.
authors.affiliation: Institute of Hematology and Blood Transfusion, Prague, Czechoslovakia.
authors.forename: T I
authors.initials: TI
authors.lastname: Pristoupil
authors.forename: T
authors.initials: T
authors.lastname: Marík
mesh_terms: D001802:Blood Substitutes; D011232:Chemical Precipitation; D004355:Drug Stability; D004591:Electrophoresis, Polyacrylamide Gel; D006454:Hemoglobins; D006801:Humans; D066298:In Vitro Techniques; D010477:Perfusion; D011489:Protein Denaturation; D012996:Solutions
chemical_list: D001802:Blood Substitutes; D006454:Hemoglobins; D012996:Solutions