[Effects of oxygenated volume expander on hemorrhagic shock].
36 dogs were divided into 3 groups: group A were administered with non-oxygenated crystalloid solution as a control; group B, with oxygenated crystalloid solution; group C, with oxygenated no 3 perfluorocarbon emulsion (PFC-O2) as volume expander. Result of measurements of serum CPK, LDH, lactic acid, gas analysis, MAP, and dynamic heart function (including pulmonary water index, LVET, LVEF, SV, CO and HR) and ultrastructural observation on lung tissue and skeletal muscles showed that oxygenated crystalloid solution can more quickly revert the hemodynamic changes after hemorrhagic shock, improves oxygen-utilizing ability of the tissue, and therefore possesses a good protective effect of the organ cells.
Yao
Z
Z
First Affiliated Hospital of Hubei Medical College, Wuhan.
D000818:Animals; D003402:Creatine Kinase / Q000097:blood*; D004285:Dogs; D005260:Female; D005466:Fluorocarbons / Q000627:therapeutic use; D006439:Hemodynamics; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008168:Lung / Q000648:ultrastructure; D008297:Male; D010100:Oxygen / Q000378:metabolism; D010952:Plasma Substitutes / Q000627:therapeutic use*; D011188:Potassium; D017680:Potassium Compounds; D012771:Shock, Hemorrhagic / Q000097:blood / Q000503:physiopathology / Q000628:therapy*
D005466:Fluorocarbons; D010952:Plasma Substitutes; D017680:Potassium Compounds; C018369:potassium cardioplegic solution; D007770:L-Lactate Dehydrogenase; D003402:Creatine Kinase; D011188:Potassium; D010100:Oxygen