Effect of malonate and p-chlorophenoxy acetic acid on hepatic succinic dehydrogenase activity of ageing lizards.
The degree of inhibition of hepatic succinic dehydrogenase activity by malonate, a competitive inhibitor, did not differ between young and middle-aged lizards. On the other hand, the same parameter increased significantly between middle-aged and old lizards. The percent inhibition of enzyme activity by p-chlorophenoxy acetic acid was also age-dependent, being higher in middle-aged and old than in young lizards.
Jena
B S
BS
Department of Zoology, Berhampur University, Orissa, India.
Patnaik
B K
BK
D000375:Aging / Q000502:physiology*; D000818:Animals; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006016:Glycolates / Q000494:pharmacology*; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects / Q000201:enzymology* / Q000378:metabolism; D008116:Lizards / Q000502:physiology*; D008297:Male; D008314:Malonates / Q000494:pharmacology*; D013385:Succinate Dehydrogenase / Q000378:metabolism*
D004791:Enzyme Inhibitors; D006016:Glycolates; D008314:Malonates; C010474:iproclozide; C030290:malonic acid; D013385:Succinate Dehydrogenase