title: Hepatic lipase activity after liver denervation in hypothyroid rats.
abstract: Hepatic hilar denervation, hepatic vagotomy or sham operation were performed in hypothyroid rats. Activities of hepatic lipase were measured nine days after surgery. Sham operation in itself was associated with a decrease of hepatic lipase activity by about 40% compared with non-operated animals. Both hilar denervation and hepatic vagotomy were associated with increased hepatic lipase activity (40% and 35%, compared with sham-operated animals). Liver contents of norepinephrine were reduced by about 90% after hilar denervation, whereas hepatic vagotomy did not affect norepinephrine levels. No major changes in lipids and lipoproteins were noted.
authors.affiliation: Department of Medicine, Malmö General Hospital, University of Lund, Sweden.
authors.forename: A L
authors.initials: AL
authors.lastname: Berg
authors.forename: L E
authors.initials: LE
authors.lastname: Hammarström
authors.forename: P
authors.initials: P
authors.lastname: Hansson
authors.forename: T
authors.initials: T
authors.lastname: Holmin
authors.forename: P
authors.initials: P
authors.lastname: Nilsson-Ehle
mesh_terms: D000818:Animals; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D003714:Denervation; D007037:Hypothyroidism / Q000139:chemically induced / Q000201:enzymology*; D008049:Lipase / Q000378:metabolism*; D008055:Lipids / Q000097:blood; D008074:Lipoproteins / Q000097:blood; D008099:Liver / Q000201:enzymology / Q000294:innervation*; D008297:Male; D009638:Norepinephrine / Q000378:metabolism; D011441:Propylthiouracil; D051381:Rats; D011919:Rats, Inbred Strains; D014628:Vagotomy
chemical_list: D008076:Cholesterol, HDL; D008055:Lipids; D008074:Lipoproteins; D011441:Propylthiouracil; D002784:Cholesterol; D008049:Lipase; D009638:Norepinephrine