[IgG subclass distribution in the serum of patients with homozygous alpha1-antitrypsin deficiency].
In 12 patients with homozygotic ZZ-phenotype alpha 1 antitrypsin deficiency, the serum levels of the IgG subclasses IgG1-4 were studied. In four of these patients, isolated or combined disorders or defects in the distribution of the IgG subclasses were detected; in cases with low IgG2 and absent IgG3, the clinical course of the disease was complicated by bronchiectasis.
Barth
J
J
Medizinische Klinik Bergmannsheil, Ruhr-Universität, Bochum.
Winkler
I
I
Schmidt
E W
EW
Braun
B E
BE
Möllmann
H W
HW
Skvaril
F
F
D000328:Adult; D000361:Agammaglobulinemia / Q000235:genetics*; D001987:Bronchiectasis / Q000235:genetics*; D005260:Female; D006720:Homozygote; D006801:Humans; D017099:IgG Deficiency; D007074:Immunoglobulin G / Q000145:classification*; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D012141:Respiratory Tract Infections / Q000235:genetics*; D019896:alpha 1-Antitrypsin Deficiency
D007074:Immunoglobulin G
IgG-Subklassenverteilung im Serum von Patienten mit homozygotem alpha 1-Antitrypsinmangel.