title: The nucleotide sequence of the equine herpesvirus 4 thymidine kinase gene.
abstract: We have determined the genomic location and nucleotide sequence of the equine herpesvirus 4 thymidine kinase (TK) gene. The gene is positioned at approximately 0.48 map units within the long unique component of the genome and is flanked by genes encoding a herpes simplex virus 1 (HSV-1) UL24 homologue and glycoprotein H. The predicted protein is composed of 352 amino acids, has an Mr of 38,800 and exhibits 36% identity to the predicted TK of HSV-1.
authors.affiliation: Department of Veterinary Pathology, University of Glasgow Veterinary School, Bearsden, U.K.
authors.forename: L
authors.initials: L
authors.lastname: Nicolson
authors.forename: A A
authors.initials: AA
authors.lastname: Cullinane
authors.forename: D E
authors.initials: DE
authors.lastname: Onions
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D006564:Herpesviridae / Q000201:enzymology / Q000235:genetics*; D008969:Molecular Sequence Data; D015183:Restriction Mapping; D012689:Sequence Homology, Nucleic Acid; D013937:Thymidine Kinase / Q000235:genetics* / Q000378:metabolism
chemical_list: D013937:Thymidine Kinase