title: [Seasonal rhythm of melatonin in manic depressive patients].
abstract: Melatonin is secreted by the pineal gland with a circadian and a circannual rhythm. For some authors the circadian rhythm is modified during depressive states. The present study evaluates the melatonin circannual rhythm in five manic-depressive patients. Each patient is clinically and biologically evaluated every month during one year. The results of the present study show a lack of clinical relapse and a lack of seasonal variation of plasma melatonin level.
authors.affiliation: Service Hospitalo-Universitaire, C.H.S. Le Vinatier, Bron.
authors.forename: F
authors.initials: F
authors.lastname: Fanget
authors.forename: J L
authors.initials: JL
authors.lastname: Terra
authors.forename: J
authors.initials: J
authors.lastname: Dalery
authors.forename: J
authors.initials: J
authors.lastname: Brun
authors.forename: B
authors.initials: B
authors.lastname: Claustrat
authors.forename: M
authors.initials: M
authors.lastname: Marie-Cardine
authors.forename: J
authors.initials: J
authors.lastname: Guyotat
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001714:Bipolar Disorder / Q000097:blood* / Q000378:metabolism / Q000503:physiopathology; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008550:Melatonin / Q000097:blood* / Q000502:physiology; D010507:Periodicity; D010870:Pineal Gland / Q000503:physiopathology; D012008:Recurrence
chemical_list: D008550:Melatonin
vernacular_title: Rythme circannuel de mélatonine chez des patients maniaco-dépressifs.