Fatal rhabdomyolysis as a complication of bone marrow transplantation.
We describe fatal rhabdomyolysis in a 24-year-old man who had received a bone marrow transplant from a sibling for the treatment of chronic granulocytic leukaemia. The rhabdomyolysis was preceded by a grand mal seizure probably caused by a combination of cyclosporin A and corticosteroids given for the prevention and treatment of acute graft-versus-host disease.
Volin
L
L
Third Department of Medicine, Helsinki University Central Hospital, Finland.
Järventie
G
G
Ruutu
T
T
D000208:Acute Disease; D000305:Adrenal Cortex Hormones / Q000009:adverse effects; D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D003524:Cyclosporins / Q000009:adverse effects; D006086:Graft vs Host Disease / Q000188:drug therapy; D006801:Humans; D007654:Ketoconazole / Q000009:adverse effects; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy / Q000601:surgery; D008297:Male; D012206:Rhabdomyolysis / Q000209:etiology*; D012640:Seizures / Q000209:etiology
D000305:Adrenal Cortex Hormones; D003524:Cyclosporins; D007654:Ketoconazole