[The pharmacokinetics and metabolism of bonnecor in rats].
The pharmacokinetics of 14C-bonnecor after intravenous and oral administration was studied. The bioavailability was 70%. It was shown that administration of doses in the range of from 3 to 43 mg/kg as well as the repeated use of bonnecor failed to influence the pharmacokinetic parameters.
Klemm
V
V
VEB Pharmazeutisches Kombinat GERMED, Dresden, DDR.
Morgenroth
U
U
Starke
F
F
Zeriatke
W
W
Ioram
U
U
D000284:Administration, Oral; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D002250:Carbon Radioisotopes; D003984:Dibenzazepines / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D004305:Dose-Response Relationship, Drug; D007275:Injections, Intravenous; D051381:Rats; D013997:Time Factors
D000889:Anti-Arrhythmia Agents; D002250:Carbon Radioisotopes; D003984:Dibenzazepines; C048166:tiracizine
Farmakokinetika i metabolizm bonnekora u krys.