title: Functional anatomy of the choroidal circulation: methyl methacrylate casting of human choroid.
abstract: The functional anatomy of the normal choroidal circulation in man is described from scanning electron microscopic examination of methyl methacrylate microvascular casts. Distal and para-optic short posterior ciliary arteries supply wedge-shaped areas of choroid. Regional variations in choriocapillary morphology are well recognised; the lobules are densely packed at the posterior pole with a high capillary to inter-capillary ratio. Choroidal capillaries are flattened providing a large surface area for metabolic exchange with the retinal pigment epithelium. In acute choroidal ischaemia (from a variety of systemic disease), wedge shaped choroidal lesions may correspond to occlusion of short posterior ciliary arteries and geographic or focal lesions to occlusion of choroidal arterioles or choriocapillary lobules.
authors.affiliation: Moorfields Eye Hospital, London.
authors.forename: J M
authors.initials: JM
authors.lastname: Olver
mesh_terms: D002196:Capillaries / Q000648:ultrastructure; D002829:Choroid / Q000098:blood supply* / Q000648:ultrastructure; D002924:Ciliary Body / Q000098:blood supply / Q000648:ultrastructure; D006801:Humans; D007511:Ischemia / Q000473:pathology; D008768:Methylmethacrylates; D008855:Microscopy, Electron, Scanning
chemical_list: D008768:Methylmethacrylates