Cephalexin in ponies: a preliminary investigation.
The administration of a single dose of the antibacterial agent cephalexin intramuscularly to six ponies at a dose rate of 7 mg/kg was well tolerated. No reactions at the injection site were apparent. It was absorbed rapidly and reached a mean peak plasma concentration of 6.77 micrograms/ml after a mean of 1.41 hours; plasma concentrations above 2.0 and 0.5 micrograms/ml were maintained for 3.8 and 9.8 hours, respectively.
Lees
P
P
Department of Veterinary Basic Sciences, Royal Veterinary College, North Mymms, Hatfield.
May
S A
SA
Hooke
R E
RE
Silley
P
P
D000042:Absorption; D000818:Animals; D002506:Cephalexin / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics*; D004361:Drug Tolerance; D005260:Female; D006207:Half-Life; D006736:Horses / Q000378:metabolism*; D007273:Injections, Intramuscular / Q000662:veterinary; D008297:Male; D012867:Skin / Q000187:drug effects
D002506:Cephalexin