Determination of dissolution profiles for several commercially available therapeutic [131I]sodium iodide capsules.
The dissolution profiles for [131I]sodium iodide therapeutic capsules from three commercial vendors were studied. The 131I release rate in water was rapid for the capsules with 100% release attained within 35 min. There was no significant difference in dissolution profiles for the capsules from the three vendors.
Yu
W K
WK
School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, Indiana.
Shaw
S M
SM
Peck
G E
GE
D002214:Capsules; D007457:Iodine Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use*; D012974:Sodium Iodide / Q000008:administration & dosage; D012995:Solubility
D002214:Capsules; D007457:Iodine Radioisotopes; D012974:Sodium Iodide