Effect of cambendazole and haloxon on the carbohydrate metabolism of Ascaridia galli and Heterakis gallinae (Nematoda).
Cambendazole 10(-4) M significantly reduced the level of glycogen in both the parasites. Lactic acid level was found enhanced. Oxygen consumption was suppressed by 63 and 94% in A. galli and H. gallinae, respectively, by 10(-4) M cambendazole. Haloxon did not cause any significant change in glycogen and lactic acid level in either parasite, but reduced oxygen consumption by 23 and 31% in Ascaridia galli and Heterakis gallinae, respectively.
Sharma
R K
RK
Postgraduate Department of Zoology, Bareilly College, India.
Singh
K
K
Saxena
K K
KK
D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology*; D001197:Ascaridia / Q000187:drug effects* / Q000378:metabolism; D001562:Benzimidazoles / Q000494:pharmacology*; D002159:Cambendazole / Q000494:pharmacology*; D050260:Carbohydrate Metabolism; D006003:Glycogen / Q000032:analysis; D007773:Lactates / Q000032:analysis; D019344:Lactic Acid; D009348:Nematoda / Q000187:drug effects* / Q000378:metabolism; D009943:Organophosphorus Compounds / Q000494:pharmacology*; D010101:Oxygen Consumption; D014468:Umbelliferones / Q000494:pharmacology*
D000871:Anthelmintics; D001562:Benzimidazoles; D007773:Lactates; D009943:Organophosphorus Compounds; D014468:Umbelliferones; D002159:Cambendazole; D019344:Lactic Acid; D006003:Glycogen; C007902:haloxon