Time trends (1980-1987) of ten selected informative morphogenetic variants in a newborn population.
The annual prevalence rates of ten selected informative morphogenetic variants (IMVs) were studied in 31,194 newborn infants over a period of 8 years (1980-1987). Two of them (preauricular sinus and ocular hypertelorism) revealed a highly significant decrease by logistic regression analysis. The other eight presented a stable pattern or small fluctuations which did not reach statistical significance. These data may serve as valuable baseline rates for monitoring IMVs in a specific newborn population. Their potential informative value as indicators of altered morphogenesis and their power for monitoring programs of environmental teratogenicity should be carefully verified.
Merlob
P
P
Department of Neonatology, Beilinson Medical Center, Petah Tiqva, Israel.
Aitkin
I
I
D000013:Congenital Abnormalities / Q000453:epidemiology* / Q000235:genetics; D005314:Embryonic and Fetal Development / Q000235:genetics; D005260:Female; D005820:Genetic Testing; D005828:Genetics, Population; D006801:Humans; D007231:Infant, Newborn; D007557:Israel; D008297:Male; D011159:Population Surveillance / Q000379:methods*; D015995:Prevalence