title: Dose calculations about shielded gynecological colpostats.
abstract: Although shielded gynecological colpostats have been shown experimentally to reduce doses to bladder and rectal tissue by as much as 50%, nearly all previously described dose computation algorithms ignore applicator heterogeneities. We describe the use of realistic Monte Carlo calculations to study the dosimetric effects of applicator structure. Use of sophisticated solid modeling techniques allows the complex internal structure of two commercially-available Fletcher-Suit colpostats, as well as that of 226Ra or 137Cs tubes, to be accurately simulated. Our results show significant differences among these source-applicator combinations. In addition, a novel dose computation algorithm for efficiently estimating absorbed dose near shielded applicators is described. Our approach is based upon empirical separation of primary- and scatter-dose components. The algorithm requires a small base of Monte Carlo-generated data, reproduces the Monte Carlo dose estimates within 3%, and is faster than Monte Carlo by a factor of 15,000. The scatter-separation method has the potential to make accurate dose estimates to bladder, rectum, tumor, and vagina available for clinical treatment planning and for extraction of more meaningful dose-response curves from clinical data.
authors.affiliation: Department of Radiation Oncology, University of Arizona, Tucson 85724.
authors.forename: J F
authors.initials: JF
authors.lastname: Williamson
mesh_terms: D001918:Brachytherapy / Q000379:methods*; D002588:Cesium Radioisotopes / Q000627:therapeutic use; D005260:Female; D005833:Genital Neoplasms, Female / Q000532:radiotherapy*; D006801:Humans; D008432:Mathematical Computing; D009010:Monte Carlo Method; D011835:Radiation Protection; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D011881:Radiotherapy, Computer-Assisted; D011883:Radium / Q000627:therapeutic use
chemical_list: D002588:Cesium Radioisotopes; D011883:Radium