Sex-linked determinants for IgM?
Evidence for a sex-linked determinant of immunoglobulin M levels was sought using correlational and commingling analyses in a sample of 174 randomly selected nuclear families. While mean IgM levels in females were approximately 25% higher than that in males, the pattern of familial correlations did not follow the expectations under a sex-linked model, and there was no commingling in the distribution of IgM levels as expected when a trait is under the influence of a major gene.
McGue
M
M
Department of Psychology, University of Minnesota, Minneapolis.
Borecki
I B
IB
Gerrard
J W
JW
Rao
D C
DC
D002170:Canada; D003198:Computer Simulation; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D007075:Immunoglobulin M / Q000235:genetics*; D008297:Male; D014960:X Chromosome
D007075:Immunoglobulin M