title: Effects of growth hormone injections on ovulation rate in ewes.
abstract: Coopworth ewes were either treated with 5 mg recombinant-derived bovine growth hormone per day for each day of the oestrous cycle or were untreated. Ovulation rates at the pre-treatment, post-treatment and a subsequent oestrus were determined by endoscopy. These were 1.34, 1.51, 1.38 for the treated ewes and 1.32, 1.43, 1.39 for the control ewes. The ovulation rate post-treatment was significantly higher than for the other two cycles in the treated ewes but it was not significantly different from the post-treatment value of the control ewes. Plasma concentrations of insulin-like growth factor-I (IGF-I) were elevated during treatment (90-130 nmol L-1) compared with concentrations of 25-50 nmol L-1 in the control ewes. No relationship was found between plasma IGF-I concentration and ovulation rate. Injection of ewes grazing ryegrass/white clover pasture with bovine growth hormone did not result in increased ovulation rate.
authors.affiliation: Ruakura Agricultural Centre, Private Bag, Hamilton, New Zealand.
authors.forename: S R
authors.initials: SR
authors.lastname: Davis
authors.forename: J F
authors.initials: JF
authors.lastname: Smith
authors.forename: P D
authors.initials: PD
authors.lastname: Gluckman
mesh_terms: D000818:Animals; D004724:Endoscopy; D004971:Estrus / Q000187:drug effects / Q000378:metabolism; D005260:Female; D013006:Growth Hormone / Q000494:pharmacology*; D007334:Insulin-Like Growth Factor I / Q000096:biosynthesis; D010060:Ovulation / Q000187:drug effects*; D012756:Sheep
chemical_list: D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone