title: Fatal pneumococcal bacteremia with disseminated intravascular coagulation and Waterhouse-Friderichsen syndrome in a vaccinated splenectomized adult. Case report.
abstract: Fatal pneumococcal bacteremia, disseminated intravascular coagulation and Waterhouse Friderichsen syndrome in a vaccinated, splenectomized adult were caused by serotype 22F (Danish classification), which was not included in the vaccine. Revaccination with a 23-valent pneumococcal vaccine and antibiotic prophylaxis are advocated for patients who have undergone splenectomy.
authors.affiliation: Second University Clinic of Internal Medicine, Kommunehospitalet, Aarhus, Denmark.
authors.forename: B E
authors.initials: BE
authors.lastname: Lindblad
authors.forename: L N
authors.initials: LN
authors.lastname: Lindblad
mesh_terms: D001428:Bacterial Vaccines; D004211:Disseminated Intravascular Coagulation / Q000209:etiology*; D005260:Female; D006801:Humans; D008589:Meningococcal Infections / Q000209:etiology*; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000209:etiology*; D022242:Pneumococcal Vaccines; D018805:Sepsis / Q000209:etiology*; D012703:Serotyping; D013156:Splenectomy; D013296:Streptococcus pneumoniae / Q000145:classification*; D014611:Vaccination; D014884:Waterhouse-Friderichsen Syndrome / Q000209:etiology*
chemical_list: D001428:Bacterial Vaccines; D022242:Pneumococcal Vaccines