[Evaluation of the development of immunologic response in patients with cutaneous leishmaniasis].
In this study we present epidemiological and immunological data about cutaneous Leishmaniasis in Panama, in an area where recurrence occurs in 65% of the cases evaluated. The development of the cellular immune response, during clinical evolution of primary and recurrent cases, indicates that initial stimulation index (SI) less than 3 are observed in recurrent cases, while this level is higher than 3 in primary cases. The humoral immune response is related only with the time of clinical evolution. We point out the importance of looking at the population of T lymphocytes quantitatively, as well as looking at the levels of lymphokines, in order to explain the differences that we observed in the cellular immune response.
de Carreira
P F
PF
Centro de Investigación y Diagnóstico de Enfermedades Parasitarias, Facultad de Medicina, Universidad de Panamá.
Suárez
M O
MO
Pascale
J M
JM
Sousa
O E
OE
D000293:Adolescent; D000917:Antibody Formation; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007223:Infant; D007896:Leishmaniasis / Q000097:blood / Q000276:immunology*; D008297:Male; D011446:Prospective Studies; D012008:Recurrence
Evaluación del desarrollo de la respuesta inmunológica en pacientes con Leishmaniasis cutánea.