title: Analysis of surgical and medical management of glaucoma in Sturge-Weber syndrome.
abstract: Management of glaucoma associated with Sturge-Weber syndrome (SWS) is difficult. The authors reviewed 36 eyes of 30 SWS patients with either early or late-onset glaucoma with a mean follow-up of 122 months (range, 24-253 months). Intervals between required surgical or medical interventions were analyzed. Intervention was attributed to elevated intraocular pressure (IOP) in 55% of cases and disc change in 45%. Median stable postoperative interval with goniotomy was 12 months; with trabeculotomy, 21 months; with trabeculectomy, 34 months; with argon laser trabeculoplasty, 25 months; and with medications, 57 months. Survival analysis shows statistically significant differences between goniotomy and medications. Intraoperative choroidal expansions developed in 24% of cases receiving a trabeculectomy, and none developed with either goniotomy or trabeculotomy.
authors.affiliation: Foundation for Glaucoma Research, San Francisco, CA 94102.
authors.forename: A G
authors.initials: AG
authors.lastname: Iwach
authors.forename: H D
authors.initials: HD
authors.lastname: Hoskins
authors.forename: J
authors.initials: J
authors.lastname: Hetherington
authors.forename: R N
authors.initials: RN
authors.lastname: Shaffer
mesh_terms: D000293:Adolescent; D000328:Adult; D000798:Angiomatosis / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D005901:Glaucoma / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D006801:Humans; D007223:Infant; D007429:Intraocular Pressure / Q000187:drug effects; D053685:Laser Therapy; D009883:Ophthalmic Solutions / Q000627:therapeutic use*; D011379:Prognosis; D012189:Retrospective Studies; D013341:Sturge-Weber Syndrome / Q000150:complications*; D014130:Trabeculectomy; D014792:Visual Acuity
chemical_list: D009883:Ophthalmic Solutions