[Detection of the activation of alveolar lymphocytes in alveolar proteinosis].
In 7 patients with pulmonary alveolar proteinosis, differential cytology and lymphocyte subsets in BAL fluid were investigated. The study showed that pulmonary alveolar proteinosis is another disorder characterized by a lymphocytic alveolitis and activation of T-lymphocytes (expression of HLA-DR antigens and IL-2 receptors). Our data indicate that immunological mechanisms involving T-cell activation may contribute to be pathogenesis of pulmonary alveolar proteinosis.
Teschler
H
H
Ruhrlandklinik Essen-Heidhausen, Medizinischen Universitätsklinik Freiburg.
Ziesche
R
R
Matthys
H
H
Greschuchna
D
D
Konietzko
N
N
Guzman
J
J
Costabel
U
U
D000328:Adult; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology; D006801:Humans; D007958:Leukocyte Count; D008213:Lymphocyte Activation / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D011649:Pulmonary Alveolar Proteinosis / Q000276:immunology*; D011658:Pulmonary Fibrosis / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*
Nachweis der Aktivierung alveolärer Lymphozyten bei Alveolarproteinose.