Cloning and sequencing of RNA of hepatitis delta virus isolated from human serum.
The RNA of hepatitis delta virus (HDV) 1682 nucleotides long, has been cloned from a human serum isolate. Comparison with the three complete published sequences shows that a region of the HDV genome, between positions 620 and 1350, which contains sequences involved in replication and possibly pathogenicity, is highly conserved.
Saldanha
J A
JA
Department of Medicine, St Mary's Hospital Medical School, London, U.K.
Thomas
H C
HC
Monjardino
J P
JP
D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D005814:Genes, Viral; D003699:Hepatitis D / Q000097:blood / Q000382:microbiology; D003698:Hepatitis Delta Virus / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D008969:Molecular Sequence Data; D002679:Pan troglodytes; D012367:RNA, Viral / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D014772:Viroids / Q000235:genetics
D012367:RNA, Viral