[Energy metabolism in the brain during experimental hemorrhagic shock].
State of energy metabolism was studied in brain of rats at agonal steps caused by bleeding during severe and long-term hypotension (30 mmHg, up to 30 hrs). Fast loss of high energy-containing phosphates, cell energy potential of adenine nucleotides and an increase in the lactate/pyruvate ratio were found in non-resistant rats. At the same time, in the most resistant rats normal content of creatine phosphate, ATP was maintained; energy potential was unaltered and anaerobic glycolysis was not activated. Content of glucose and glycogen did not alter considerably in all the animals studied.
Loginova
M P
MP
Assur
M V
MV
Boldina
I G
IG
D000227:Adenine Nucleotides / Q000378:metabolism; D000818:Animals; D001794:Blood Pressure; D001921:Brain / Q000378:metabolism*; D004734:Energy Metabolism; D008297:Male; D010084:Oxidation-Reduction; D051381:Rats; D012771:Shock, Hemorrhagic / Q000378:metabolism* / Q000503:physiopathology
D000227:Adenine Nucleotides
Sostoianie énergeticheskogo obmena mozga pri éksperimental'nom gemorragicheskom shoke.