title: Responses of astrocytes in culture after low dose laser irradiation.
abstract: The effect of Helium-Neon low dose laser on astrocytes was investigated in cultures of isolated astrocytes from albino neonatal rats. The laser appeared to inhibit the growth of astrocytes as exemplified by the smaller sizes of the cells and the decreased leucine uptake in each cell after treatment. Temporary decrease in the number of mitoses was also observed, but this trend was reversed soon after. Electron microscopic studies revealed an increase in buddings from cell bodies and processes (branches) after irradiation.
authors.affiliation: Department of Anatomy, Chinese University of Hong Kong, Shatin, N.T.
authors.forename: D T
authors.initials: DT
authors.lastname: Yew
authors.forename: D R
authors.initials: DR
authors.lastname: Zheng
authors.forename: C
authors.initials: C
authors.lastname: Au
authors.forename: W W
authors.initials: WW
authors.lastname: Li
mesh_terms: D000818:Animals; D001253:Astrocytes / Q000378:metabolism / Q000528:radiation effects* / Q000648:ultrastructure; D002478:Cells, Cultured; D004307:Dose-Response Relationship, Radiation; D005904:Glial Fibrillary Acidic Protein / Q000378:metabolism; D006371:Helium / Q000528:radiation effects; D007150:Immunohistochemistry; D007834:Lasers; D007930:Leucine / Q000378:metabolism; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D009356:Neon / Q000528:radiation effects; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D005904:Glial Fibrillary Acidic Protein; D006371:Helium; D009356:Neon; D007930:Leucine