title: [Ultrastructure of the liver and endocrine system in aging rats: effect of piracetam].
abstract: Lipogenic pigmentation is described in thyroid follicular, parathyroid, and pineal cells, as well as in adrenocortical macrophages. Piracetam activated pituitary prolactin cells and increased paracrystals in thyroid follicular cells; smooth endoplasmic reticulum was increased and glycogen content decreased in numerous hepatocytes randomly distributed over the lobule.
authors.affiliation: Institut für Pharmakologie und Toxikologie, Fakultät für Klinische Medizin Mannheim, Universität Heidelberg.
authors.forename: E
authors.initials: E
authors.lastname: Schiller
mesh_terms: D000302:Adrenal Cortex / Q000187:drug effects; D000818:Animals; D002470:Cell Survival / Q000187:drug effects*; D003594:Cytoplasmic Granules / Q000187:drug effects; D004702:Endocrine Glands / Q000187:drug effects*; D005609:Free Radicals; D008062:Lipofuscin / Q000378:metabolism; D008099:Liver / Q000187:drug effects*; D008264:Macrophages / Q000187:drug effects; D010280:Parathyroid Glands / Q000187:drug effects; D010870:Pineal Gland / Q000187:drug effects; D051381:Rats; D013961:Thyroid Gland / Q000187:drug effects
chemical_list: D005609:Free Radicals; D008062:Lipofuscin
vernacular_title: Ultrastruktur von Leber und Inkretsystem alter Ratten: Einfluss von Piracetam.