Effects of alfentanil on induction and recovery from propofol anaesthesia in day surgery.
The influence of alfentanil on induction and recovery characteristics of propofol was examined in women presenting as day cases for minor gynaecological surgery. Alfentanil reduced the incidence of pain on injection and the induction and maintenance requirements of propofol. This was at the expense of more prolonged apnoea. Immediate recovery characteristics were similar in each group although changes in Critical Flicker Fusion Threshold as a measure of psychomotor impairment were more pronounced after alfentanil. Such differences were insignificant at three hours by which time Critical Flicker Fusion Threshold had returned to baseline and patients were ready for discharge home.
Wall
R J
RJ
Southland Hospital, Kew, Invercargill, New Zealand.
Zacharias
M
M
D000328:Adult; D015760:Alfentanil / Q000008:administration & dosage / Q000494:pharmacology; D000556:Ambulatory Surgical Procedures; D000762:Anesthesia Recovery Period; D000771:Anesthesia, Intravenous; D001049:Apnea / Q000139:chemically induced; D001794:Blood Pressure / Q000187:drug effects; D005260:Female; D005425:Flicker Fusion / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D011229:Preanesthetic Medication; D015742:Propofol / Q000008:administration & dosage / Q000494:pharmacology; D011897:Random Allocation; D012018:Reflex / Q000187:drug effects; D012119:Respiration / Q000187:drug effects
D015760:Alfentanil; D015742:Propofol