The immunosuppressive agent 15-deoxyspergualin induces tolerance and modulates MHC-antigen expression and interleukin-1 production in the early phase of rat allograft responses.
Waaga
A M
AM
Department of Immunology, Medical School, University of Kiel, FRG.
Ulrichs
K
K
Krzymanski
M
M
Treumer
J
J
Hansmann
M L
ML
Rommel
T
T
Müller-Ruchholtz
W
W
D000818:Animals; D015870:Gene Expression; D006084:Graft Rejection; D006085:Graft Survival; D006146:Guanidines / Q000494:pharmacology*; D015395:Histocompatibility Antigens Class I / Q000235:genetics; D007108:Immune Tolerance; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007375:Interleukin-1 / Q000096:biosynthesis*; D016030:Kidney Transplantation / Q000276:immunology*; D008285:Major Histocompatibility Complex / Q000187:drug effects*; D051381:Rats; D011917:Rats, Inbred Lew; D011919:Rats, Inbred Strains; D016038:Skin Transplantation / Q000276:immunology*; D014184:Transplantation, Homologous / Q000276:immunology
D006146:Guanidines; D015395:Histocompatibility Antigens Class I; D007166:Immunosuppressive Agents; D007375:Interleukin-1; C037258:gusperimus