[Increase in the activity of nuclear DNA polymerases in the tissues of mice subjected to long-term gamma irradiation].
Activity of nuclear DNA-polymerase in the liver, lung and spleen tissues of mice subjected to long-term chronic gamma-irradiation (1.3 mGy/h) has been investigated. Chronic gamma-irradiation with a cumulative dose of 1.7 Gy during 55 days raises DNA polymerase activity in the irradiated tissue nuclei. Analysis of DNA-polymerase activity in the liver nuclei have demonstrated that this increase is connected with activation of DNA-polymerase beta.
Kozhanovskaia
Ia K
IaK
Fomenko
L A
LA
Gaziev
A I
AI
D000818:Animals; D002467:Cell Nucleus / Q000201:enzymology*; D002588:Cesium Radioisotopes; D004259:DNA-Directed DNA Polymerase / Q000378:metabolism*; D005720:Gamma Rays; D008099:Liver / Q000201:enzymology; D008168:Lung / Q000201:enzymology; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D011833:Radiation Injuries, Experimental / Q000201:enzymology*; D013154:Spleen / Q000201:enzymology; D013997:Time Factors
D002588:Cesium Radioisotopes; D004259:DNA-Directed DNA Polymerase
Povyshenie aktivnosti iadernykh DNK-polimeraz v tkaniakh mysheĭ, podvergnutykh dlitel'nomu gamma-oblucheniiu.