title: [Oxygen radical production by alveolar macrophages in sarcoidosis in relation to activity status of bronchoalveolar lavage lymphocytes].
abstract: Mediators of lymphocytic alveolitis in sarcoidosis are able to activate alveolar macrophages. In sarcoidosis, there is a pre-activation of the alveolar macrophages, which is reflected in an elevated production of O2 by the alveolar macrophages. There is a positive correlation between this radical load in the distal respiration tract and parameters of lymphocytic alveolitis.
authors.affiliation: III. Medizinische Klinik-Schwerpunkt Pneumologie, Universitätskliniken Mainz.
authors.forename: J
authors.initials: J
authors.lastname: Strausz
authors.forename: J
authors.initials: J
authors.lastname: Müller-Quernheim
authors.forename: H
authors.initials: H
authors.lastname: Steppling
authors.forename: M
authors.initials: M
authors.lastname: Nagel
authors.forename: R
authors.initials: R
authors.lastname: Ferlinz
mesh_terms: D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology*; D005609:Free Radicals; D006801:Humans; D008163:Luminescent Measurements; D008171:Lung Diseases / Q000276:immunology*; D008213:Lymphocyte Activation / Q000276:immunology*; D008262:Macrophage Activation / Q000276:immunology*; D008264:Macrophages / Q000276:immunology*; D010101:Oxygen Consumption / Q000502:physiology*; D011650:Pulmonary Alveoli / Q000276:immunology*; D012507:Sarcoidosis / Q000276:immunology*
chemical_list: D005609:Free Radicals
vernacular_title: Sauerstoffradikalproduktion durch Alveolarmakrophagen (AM) bei Sarkoidose in Abhängigkeit des Aktivitätsstatus der bronchoalveolären Lavage Lymphozyten.