title: Comparison of the iodide permeability test, the surface microhardness test, and mineral dissolution of bovine enamel following acid challenge.
abstract: The relationship among the iodide permeability (Ip) test, the surface microhardness (SMH) test, and enamel demineralization chemically analyzed as mineral loss was investigated using bovine enamel blocks. Demineralization periods of 0 (control) and 5, 15, 30, and 45 min using 0.05 mol/l lactate (pH 4.75) were chosen to approximate the acid challenge occurring during the intraoral enamel demineralization test. Mineral loss (Ca and PO4) was found to be directly proportional to dissolution time (r = 0.95). Changes (delta) in Ip and SMH each increased linearly over time (r = 0.58 and 0.64, respectively) and were similarly related to mineral loss (r = 0.60 and 0.65, respectively). The correlation between delta Ip and delta SMH was 0.55. When longer demineralization periods (60, 120, and 240 min) were included, the correlation between delta Ip and delta SMH was 0.68. We conclude that both the Ip test and the SMH test can be used as measures of the early stages of enamel dissolution.
authors.affiliation: Eastman Dental Center, Rochester, N.Y.
authors.forename: D T
authors.initials: DT
authors.lastname: Zero
authors.forename: I
authors.initials: I
authors.lastname: Rahbek
authors.forename: J
authors.initials: J
authors.lastname: Fu
authors.forename: H M
authors.initials: HM
authors.lastname: Proskin
authors.forename: J D
authors.initials: JD
authors.lastname: Featherstone
mesh_terms: D000818:Animals; D002118:Calcium / Q000032:analysis; D002417:Cattle; D003731:Dental Caries / Q000473:pathology*; D003745:Dental Enamel Permeability; D003747:Dental Enamel Solubility; D006245:Hardness Tests; D006863:Hydrogen-Ion Concentration; D007454:Iodides; D007773:Lactates; D019344:Lactic Acid; D010710:Phosphates / Q000032:analysis; D012044:Regression Analysis; D014088:Tooth Permeability
chemical_list: D007454:Iodides; D007773:Lactates; D010710:Phosphates; D019344:Lactic Acid; D002118:Calcium