Danazol induced pancreatitis and hepatitis.
Danazol, a C17 alkylated anabolic steroid, has been tried as a hormonomodulator in the management of systemic lupus erythematosus. We report the case of a patient receiving 400 mg of danazol per day who developed mild pancreatitis associated with hepatitis, both induced by danazol.
Chevalier
X
X
Clinique de Rhumatologie, Hôpital Cochin, Paris.
Awada
H
H
Baetz
A
A
Amor
B
B
D000082:Acetaminophen / Q000627:therapeutic use; D000328:Adult; D056486:Chemical and Drug Induced Liver Injury; D002927:Cimetidine / Q000627:therapeutic use; D003613:Danazol / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy; D010195:Pancreatitis / Q000139:chemically induced*; D011245:Pregnadienes / Q000009:adverse effects*
D011245:Pregnadienes; D000082:Acetaminophen; D002927:Cimetidine; D003613:Danazol