[Neonatal lupus].
Neonatal lupus erythematosus is characterized by congenital atrioventricular heart block and/or transient lupus skin lesions frequently similar to those seen in patients with subacute cutaneous lupus erythematosus. The mothers have anti-SSA (Ro) and/or anti-SSB (La) antibodies. The syndrome is important to recognize because newborns may develop complete heart block with congestive heart failure. However, in the majority of cases, neonatal lupus erythematosus is a relatively benign disorder and cutaneous lesions generally disappear completely by 6 months of age.
de Prost
Y
Y
Service de Dermatologie, Hôpital Necker, Paris.
Bodemer
C
C
D001323:Autoantibodies / Q000502:physiology; D005260:Female; D006327:Heart Block / Q000209:etiology; D006330:Heart Defects, Congenital / Q000209:etiology / Q000276:immunology; D006331:Heart Diseases / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000151:congenital* / Q000276:immunology; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology; D011379:Prognosis; D012871:Skin Diseases / Q000209:etiology / Q000473:pathology
D001323:Autoantibodies
Lupus néonatal.