Surface modification of polystyrene--platelet adhesion.
Indomethacine is an analgesic and antiinflammatory drug which has antiplatelet and antithrombotic properties. In our work, we have tried to immobilize the same onto a polymer surface covalently. Surface parameters like water contact angle and platelet adhesion are studied. Similar studies are conducted on heparin immobilized surfaces, for relative comparison.
Sharma
C P
CP
Biosurface Technology Division, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Poojapura, Trivandrum, India.
Hari
P R
PR
D000418:Albumins; D000818:Animals; D001672:Biocompatible Materials; D002417:Cattle; D007213:Indomethacin / Q000494:pharmacology; D008422:Materials Testing; D008970:Molecular Weight; D010973:Platelet Adhesiveness / Q000187:drug effects / Q000502:physiology*; D011137:Polystyrenes; D013499:Surface Properties
D000418:Albumins; D001672:Biocompatible Materials; D011137:Polystyrenes; D007213:Indomethacin