[Incoercible hemorrhagic cystitis induced by pelvic radiotherapy and simultaneous treatment with cyclophosphamide].
We present a case of incoercible hemorrhagic cystitis provoked by the therapeutic association of systemic cyclophosphamide and pelvic radiotherapy in a woman with disseminated mammary carcinoma disease. The conservative treatment, including vesical irrigation with aluminum salts, did not succeed in stopping the bleeding. A "sauvatage" cystectomy was carried out with Bricher-Wallace II type urinary derivation. We conclude by pointing out how the simultaneity of two therapies with individual vesical toxicity risk were boosted and how cystectomy continues to be the definitive treatment once conservative measures have been used up.
González Enguita
C
C
Servicio de Urología, Hospital Miguel Servet, Zaragoza.
Gil Sanz
M J
MJ
Rodríguez Vela
L
L
Pérez Salinas
V
V
Roncalés Badal
A
A
Allepuz Losa
C
C
Martínez Bengoechea
J
J
Rioja Sanz
C
C
Rioja Sanz
L A
LA
D003520:Cyclophosphamide / Q000009:adverse effects*; D003556:Cystitis / Q000209:etiology*; D005260:Female; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D011832:Radiation Injuries / Q000209:etiology*; D001743:Urinary Bladder / Q000187:drug effects* / Q000528:radiation effects*; D001745:Urinary Bladder Diseases / Q000209:etiology
D003520:Cyclophosphamide
Cistitis hemorrágica incoercible inducida por la radioterapia pelviana y tratamiento simultáneo con ciclofosfamida.