title: [A case of demyelinating disease showing a peculiar honeycomb-like and lamellar structure on magnetic resonance imaging].
abstract: A case of subacute demyelinating disease showing large honeycomb-like and lamellar lesions in bilateral cerebral white matter on MRI was reported. A 22 year-old woman felt general fatigue on sept. 30, 1988, and developed complete quadriplegia and mutism in about 10 days. She recovered shortly after high-dose corticosteroid therapy. She had neither fever nor meningeal irritation. There were no inflammatory changes in examinations of blood and CSF. On MRI, high and low signal areas of irregular shape in the cerebral white matter and brainstem, were observed on T2 and T1 weighted images, respectively, suggesting that the lesions are of demyelinating nature. These lesions appeared lamellar or honeycomb-like structures on T1 and T2 weighted image. This patient was diagnosed as having a subacute type of demyelinating disease similar to Balo's disease (concentric sclerosis).
authors.affiliation: Department of Neurology, Faculty of Medicine, Kyushu University.
authors.forename: K
authors.initials: K
authors.lastname: Miyata
authors.forename: Y
authors.initials: Y
authors.lastname: Itoyama
authors.forename: T
authors.initials: T
authors.lastname: Kobayashi
authors.forename: K
authors.initials: K
authors.lastname: Yasumori
authors.forename: I
authors.initials: I
authors.lastname: Goto
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology*; D003711:Demyelinating Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D003907:Dexamethasone / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging
chemical_list: D003907:Dexamethasone