title: Number, volume and size distribution of nucleoli in rat neurosecretory cells with suppressed and stimulated secretion.
abstract: The nucleoli in the neurons of the supraoptic nucleus were investigated in the rat. This was performed after the secretion of vasopressin had been suppressed by water load, after the secretion had been stimulated by water deprival and in normal rats which had water ad libitum. The cells with high secretory activity had large single nucleoli. The cells with low secretory activity had less nucleolar volume, and a substantial part of the cells contained two nucleoli.
authors.affiliation: Anatomy Department C, University of Copenhagen, Denmark.
authors.forename: L
authors.initials: L
authors.lastname: Andersen
mesh_terms: D000284:Administration, Oral; D000818:Animals; D002466:Cell Nucleolus / Q000187:drug effects / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D009474:Neurons / Q000187:drug effects / Q000648:ultrastructure; D009490:Neurosecretory Systems / Q000166:cytology* / Q000378:metabolism / Q000648:ultrastructure; D051381:Rats; D013495:Supraoptic Nucleus / Q000166:cytology / Q000378:metabolism / Q000648:ultrastructure; D014667:Vasopressins / Q000378:metabolism; D014867:Water / Q000008:administration & dosage
chemical_list: D014867:Water; D014667:Vasopressins