title: Automated volume determination of the liver and spleen from Tc-99m colloid SPECT imaging. Quantification of the liver functional and nonfunctional tissue in disease.
abstract: An automated volume determination program using SPECT imaging with Tc-99m has been validated by both phantom and patient studies. Its use for monitoring change of function of the liver and change in tumor mass during different therapy regimes has been assessed. The technique is not restricted to the estimation of the hepatic functioning tissues; it therefore has many potential clinical implementations for volume determination in other organs.
authors.affiliation: Department of Nuclear Medicine, Hospital of the Good Samaritan, Los Angeles, California.
authors.forename: G J
authors.initials: GJ
authors.lastname: Kavanagh
authors.forename: J T
authors.initials: JT
authors.lastname: Kavanagh
authors.forename: P B
authors.initials: PB
authors.lastname: Kavanagh
authors.forename: L E
authors.initials: LE
authors.lastname: Irwin
authors.forename: A C
authors.initials: AC
authors.lastname: Perkins
authors.forename: L A
authors.initials: LA
authors.lastname: Swanson
mesh_terms: D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D008961:Models, Structural; D008991:Monitoring, Physiologic / Q000379:methods; D012984:Software; D013154:Spleen / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D013671:Technetium Tc 99m Sulfur Colloid; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D013671:Technetium Tc 99m Sulfur Colloid