[Fatal hemoptysis during bronchial aspergillosis with multiple pulmonary artery aneurysms].
Aspergillosis with fatal outcome are usually pulmonary invasive aspergillosis with or without dissemination, developed in patients with severe immunosuppression. We report a fatal case of bronchial necrotizing aspergillosis in a young woman with diabetes mellitus, who developed similar lesions to "Semi-invasive Aspergillosis", so-called "Chronic Necrotizing Pulmonary Aspergillosis". This aspergillosis was complicated by large pulmonary artery aneurysms requiring an hemostatic lobectomy. These aneurysms, secondary to the bronchial lesions, contrast with infectious aneurysms (so-called mycotic) secondary to septic embols. They differ from Rasmussen's aneurysms, due to tuberculosis, by their size, fusiform shape and extent. Lesions of vessels' walls and parietal fungal invasion in the vicinity of an endo-bronchial aspergilloma explain the vascular rupture. The multiplicity of these aneurysms, showed on C T Scan, is responsible for death by post-surgical recurrence of hemoptysis.
Caulet
S
S
Service Central d'Anatomie et de Cytologie Pathologiques Jacques Delarue, Hôtel-Dieu, Paris.
Capron
F
F
Laaban
J P
JP
Prudent
J
J
Rochemaure
J
J
Diebold
J
J
D000328:Adult; D000783:Aneurysm / Q000150:complications* / Q000473:pathology; D001228:Aspergillosis / Q000150:complications* / Q000473:pathology; D001982:Bronchial Diseases / Q000150:complications / Q000473:pathology; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D005260:Female; D006469:Hemoptysis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008168:Lung / Q000473:pathology; D008172:Lung Diseases, Fungal / Q000150:complications* / Q000473:pathology; D011651:Pulmonary Artery / Q000473:pathology
Hémoptysie fatale au cours d'une aspergillose bronchique par anévrysmes artériels pulmonaires multiples.