title: [Surfactant phospholipids in bronchoalveolar lavage fluid in smokers with healthy lungs and non-smokers].
abstract: The surfactant phospholipids were determined in the BA1 fluid of 9 smokers and 9 non-smokers with no disease of the lungs. The total phospholipid content was reduced significantly in smokers to 10 +/- 6 nmol/ml as compared with 24 +/- 10 nmol/ml in the non-smokers (p less than 0.02). The composition of major phospholipid fractions (phosphatidyl-choline and phosphatidyl-ethanolamine) did not differ between the two groups. Possible reasons for this reduction of surfactant in smokers are discussed.
authors.affiliation: Abteilung Pneumologie, Universitätsklinik Freiburg.
authors.forename: G
authors.initials: G
authors.lastname: Würtemberger
authors.forename: R
authors.initials: R
authors.lastname: Herceg
authors.forename: H
authors.initials: H
authors.lastname: Matthys
authors.forename: E
authors.initials: E
authors.lastname: Ferber
authors.forename: U
authors.initials: U
authors.lastname: Costabel
mesh_terms: D001992:Bronchoalveolar Lavage Fluid / Q000032:analysis*; D006801:Humans; D010713:Phosphatidylcholines / Q000032:analysis; D010714:Phosphatidylethanolamines / Q000032:analysis; D010743:Phospholipids / Q000032:analysis*; D011663:Pulmonary Surfactants / Q000032:analysis*; D012907:Smoking / Q000009:adverse effects*
chemical_list: D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D010743:Phospholipids; D011663:Pulmonary Surfactants
vernacular_title: Surfactant-Phospholipide der BAL-Flüssigkeit bei lungengesunden Rauchern und Nichtrauchern.