title: Local antibiotic treatment of soft tissue and bone infections of the foot.
abstract: Twenty-seven pedal soft tissue and bone infections in 26 patients were treated with surgical necrectomy of infected tissues and implantation of antibiotic-loaded polymethyl methacrylate bone cement beads on chains. The definitive diagnosis of the infected tissues was obtained by culture and histologic examination in all of the cases. A wide variety of foot infections was successfully treated in this manner. The success rate without recurrence of osteomyelitis or soft tissue infection was 95% in this study at an average of 16 months after surgery.
authors.affiliation: Deaconess Hospital, St. Louis, MO.
authors.forename: D E
authors.initials: DE
authors.lastname: Stabile
authors.forename: A M
authors.initials: AM
authors.lastname: Jacobs
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy*; D001843:Bone Cements; D001864:Bone Wires; D004343:Drug Implants; D005260:Female; D005500:Follow-Up Studies; D005534:Foot Diseases / Q000188:drug therapy* / Q000601:surgery; D005839:Gentamicins / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000188:drug therapy* / Q000517:prevention & control / Q000601:surgery; D012008:Recurrence; D013530:Surgical Wound Infection / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents; D001843:Bone Cements; D004343:Drug Implants; D005839:Gentamicins