[Morphometric characteristics of hepatocyte mitochondria during internal administration of boron-containing water].
The changes of hepatic mitochondrial cells were studied in white male rats during internal application of boron-containing waters, having 250 mg/l concentration of boron, but different ionic-salt basis. Mitochondrial hepatocytes and hepatic boron content relationships were established. It was shown that during boron accumulation in liver (15 applications) decreasing of mitochondrial size occurred, independently, of the type of boron-containing waters. During stable boron level and particularly during its excretion from organism (24 applications, 6 days aftereffect), increase of size of mitochondria and their ellipticity, change of configuration, that depend on the type of applied waters was shown.
Korolev
Iu N
IuN
Panova
L N
LN
Zhukotskiĭ
A V
AV
Butusova
N N
NN
Kogan
E M
EM
D000818:Animals; D001895:Boron / Q000008:administration & dosage / Q000009:adverse effects* / Q000032:analysis; D008099:Liver / Q000032:analysis / Q000187:drug effects; D008297:Male; D008930:Mitochondria, Liver / Q000187:drug effects / Q000648:ultrastructure*; D008954:Models, Biological; D051381:Rats; D013053:Spectrophotometry; D014881:Water Supply
D001895:Boron
Morfometricheskaia kharakteristika mitokhondriĭ gepatotsitov pri vnutrennem primeneniem borsoderzhashchikh vod.