[Comparative evaluation of the antiviral efficacy of virazole and ribamidil in experimental Lassa fever in monkeys].
Lassa virus administered to monkeys aerogenically induced in these laboratory animals a fatal disease modelling the severe course of human Lassa fever. It was demonstrated experimentally that ribamydil, a Soviet analogue of virasol, as well as foreign commercial virasol was therapeutically effective in experimental Lassa fever in aerogenically infected monkeys.
Dvoretskaia
V I
VI
Evseev
A A
AA
Bogatikov
G V
GV
Pshenichnov
V A
VA
D000818:Animals; D004353:Drug Evaluation, Preclinical; D007273:Injections, Intramuscular; D007835:Lassa Fever / Q000188:drug therapy* / Q000401:mortality; D010215:Papio; D012254:Ribavirin / Q000627:therapeutic use*; D012263:Ribonucleosides / Q000627:therapeutic use*
D012263:Ribonucleosides; D012254:Ribavirin
Sravnitel'naia otsenka protivovirusnoĭ éffektivnosti virazola i ribamidila pri éksperimental'noĭ likhoradke Lassa u obez'ian.