Hypertension in sickle cell disease.
We report a young male with sickle cell trait who developed severe hypertension and splenic infarction soon after travel to a high altitude. Hypertension persisted for three days after a diagnostic laparotomy. His blood pressure then continued to be normal over the next one and a half years. Red cell sludging in the small vessels of the kidney possibly activated the renin angiotensin system.
Narasimhan
C
C
Department of Medicine Unit-I, CMC Hospital, Vellore, Tamil Nadu.
George
T
T
George
J T
JT
Pulimood
B M
BM
D000328:Adult; D000532:Altitude Sickness / Q000209:etiology; D000755:Anemia, Sickle Cell / Q000150:complications*; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D008297:Male; D012805:Sickle Cell Trait / Q000150:complications*; D013159:Splenic Infarction / Q000209:etiology*