title: [An autopsy case of lethal midline granuloma that terminated in an intracranial hemorrhage].
abstract: Reported is an autopsy case of a lethal midline granuloma (LMG) that originally had been manifested as chronic sinusitis and that terminated in intracranial hemorrhage. A 30-year-old woman developed a necrosis of the nasal cavity while being treated for chronic sinusitis for approximately four months. She subsequently died of an intracranial hemorrhage, and an autopsy revealed a necrosis that had progressed from the nasal cavity to the frontal base of the brain, and an infiltration of atypical cells that had an immunoreactivity to the T-cell antigens was observed. Recent studies have strongly suggested the possibility that some cases of an LMG, if not all, may be identical to a T-cell lymphoma. Our case is described and this disease is discussed.
authors.affiliation: 1st Dept. of Pathology, Kagawa Med. School.
authors.forename: A
authors.initials: A
authors.lastname: Kurose
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: M
authors.initials: M
authors.lastname: Ohmori
authors.forename: H
authors.initials: H
authors.lastname: Uda
authors.forename: M
authors.initials: M
authors.lastname: Miyaguchi
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000209:etiology / Q000473:pathology*; D005260:Female; D006103:Granuloma, Lethal Midline / Q000150:complications / Q000473:pathology*; D006801:Humans