title: Oxytoxins, bioactive molecules produced by the marine opisthobranch mollusc Oxynoe olivacea from a diet-derived precursor.
abstract: The ethereal extract of the mucous secretion from the opisthobranch mollusc Oxynoe olivacea was examined and found to contain two novel ichthyotoxic compounds, named oxytoxin 1 and 2 (1,2). The structures of 1 and 2 are closely related to the metabolites previously isolated from the alga Caulerpa prolifera. The activity of the most stable compound was studied in order to investigate the possibility of a further biological role for these metabolites, which represent an uncommon example of bioactive molecules produced in vivo from a dietary precursor.
authors.affiliation: Istituto per la Chimica di Molecole d'Interesse Biologico, Napoli, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Cimino
authors.forename: A
authors.initials: A
authors.lastname: Crispino
authors.forename: V
authors.initials: V
authors.lastname: Di Marzo
authors.forename: M
authors.initials: M
authors.lastname: Gavagnin
authors.forename: J D
authors.initials: JD
authors.lastname: Ros
mesh_terms: D000447:Aldehydes; D000818:Animals; D004032:Diet; D056890:Eukaryota; D009682:Magnetic Resonance Spectroscopy; D008974:Mollusca / Q000032:analysis* / Q000378:metabolism; D008978:Mollusk Venoms / Q000302:isolation & purification* / Q000378:metabolism; D014118:Toxins, Biological / Q000302:isolation & purification* / Q000378:metabolism
chemical_list: D000447:Aldehydes; D008978:Mollusk Venoms; D014118:Toxins, Biological