[HLA and otosclerosis].
The HLA antigens frequencies were studied in 30 Japanese patients with otosclerosis, and were compared with those of 220 randomly-selected apparently healthy unrelated Japanese. Serological HLA typing was performed by the modified two-stage complement-dependent microcytotoxicity method at the Blood Transfusion Service, Tokyo University Hospital. The results were as follows: There was no significant deviation of HLA class I antigen frequencies in the patients tested as compared with those in controls. As for HLA class II antigens, the DRw11 antigens frequency showed slight increase; however, after the correction of the P value, this was not significant.
Nibu
K
K
Department of Otolaryngology, National Tohsei Hospital, Sizuoka.
Okuno
T
T
Nomura
Y
Y
Matsuki
K
K
Juji
T
T
D000328:Adult; D000368:Aged; D016009:Chi-Square Distribution; D005260:Female; D006680:HLA Antigens / Q000378:metabolism*; D006684:HLA-DR Antigens / Q000378:metabolism; D059810:HLA-DR Serological Subtypes; D006801:Humans; D008297:Male; D008875:Middle Aged; D010040:Otosclerosis / Q000276:immunology*
D006680:HLA Antigens; D006684:HLA-DR Antigens; D059810:HLA-DR Serological Subtypes; C080766:HLA-DR11 antigen