title: Generalized motor seizures after portosystemic shunt ligation in dogs: five cases (1981-1988).
abstract: Severe generalized motor seizures developed in 5 dogs between 13 hours and 3 days after surgical attenuation of a single extrahepatic portosystemic shunt. Three dogs died, and a fourth was euthanatized because of poor prognosis for recovery. The fifth dog, although improved, was still not clinically normal 15 months after surgery. An intra-or extracranial cause for the seizures could not be identified in any of these dogs. Postmortem examination results in 3 dogs were similar to findings previously reported in dogs with portosystemic shunts, but which did not undergo surgical shunt ligation. Of the 5 dogs, 4 were greater than 18 months old, which may indicate that older dogs are more likely to develop seizures after shunt ligation than are younger dogs.
authors.affiliation: Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison 53706.
authors.forename: K J
authors.initials: KJ
authors.lastname: Matushek
authors.forename: D
authors.initials: D
authors.lastname: Bjorling
authors.forename: K
authors.initials: K
authors.lastname: Mathews
mesh_terms: D000818:Animals; D001401:Azygos Vein / Q000002:abnormalities / Q000601:surgery; D004283:Dog Diseases / Q000209:etiology* / Q000601:surgery; D004285:Dogs / Q000002:abnormalities; D005260:Female; D008026:Ligation; D008297:Male; D011168:Portal System / Q000002:abnormalities* / Q000601:surgery; D011169:Portal Vein / Q000002:abnormalities / Q000601:surgery; D011183:Postoperative Complications / Q000209:etiology / Q000662:veterinary*; D012189:Retrospective Studies; D012640:Seizures / Q000209:etiology / Q000662:veterinary*