title: Parathyroid autotransplantation in total thyroidectomy.
abstract: Although parathyroid autotransplantation during the course of thyroidectomy was first described by Halsted in 1907, it is only during the past 20 years that this simple and effective method of preserving parathyroid function is being used by an increasing number of surgeons. Our group has autotransplanted normal parathyroids since 1965, whenever these glands could not be preserved in situ with adequate blood supply. With increasing experience, we find it much simpler to autotransplant parathyroid glands attached to the thyroid, than to dissect their precarious blood supply, hoping they will survive postoperative edema and fibrosis. Furthermore, it is our impression that in operations for thyroid carcinoma, attempts to preserve the blood supply to the parathyroids may compromise the completeness of the thyroidectomy or of the dissection of cervical nodes in the tracheoesophageal groove. In a review of our experience during the past four years (January 1, 1984 to December 31, 1988), 87 patients underwent total thyroidectomy. Parathyroid glands that could not be saved in situ were biopsied to confirm their identity by frozen section and autotransplanted in the ipsilateral sternocleidomastoid muscle. Among the 87 patients undergoing total thyroidectomy, 34 required no autotransplantation, whereas 52 had one to three glands autotransplanted, and one had four glands autotransplanted. Postoperatively, 23 patients (26 percent) developed hypocalcemia, whereas 18 required CaCO3 and five required vitamin D in addition. All patients (98%) except two had normal parathyroid function at four-month follow-up and thereafter, as judged by serum calcium, phosphorus and parathormone, when indicated.
authors.affiliation: Department of Surgery, Loyola University Stritch School of Medicine, Maywood, Illinois.
authors.forename: M A
authors.initials: MA
authors.lastname: Smith
authors.forename: H
authors.initials: H
authors.lastname: Jarosz
authors.forename: P
authors.initials: P
authors.lastname: Hessel
authors.forename: A M
authors.initials: AM
authors.lastname: Lawrence
authors.forename: E
authors.initials: E
authors.lastname: Paloyan
mesh_terms: D000328:Adult; D002118:Calcium / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006996:Hypocalcemia / Q000209:etiology / Q000628:therapy; D008297:Male; D010280:Parathyroid Glands / Q000637:transplantation*; D013964:Thyroid Neoplasms / Q000601:surgery*; D013965:Thyroidectomy / Q000009:adverse effects / Q000379:methods*; D014182:Transplantation, Autologous; D014807:Vitamin D / Q000627:therapeutic use
chemical_list: D014807:Vitamin D; D002118:Calcium