[Effect of body weight and acute mesenteric ischemia duration on the mortality of rats subjected to intestinal revascularization].
We have studied the influence of corporal weight and acute mesenteric ischemia (AMI) duration on the mortality and average survival of rats submitted to intestinal revascularization. The results demonstrated that mortality is under 50% when the AMI is equal or less than 2 hours. There are also important differences in mortality, for the same AMI duration, depending on the corporal weight and age of the animals. The differences are statistically significant up to 210 g. In conclusion, in experimental studies on intestinal ischemia-revascularization, it is necessary to correct for factors as ischemia duration and weight, which are variables that can alter the results.
Ortiz Lacorzana
J
J
Cátedra de Patología y Clínica Quirúrgicas (Laboratorio de Cirugía Experimental), Facultad de Medicina y Ondontología, Universidad del País Vasco.
García-Alonso Montoya
I
I
Portugal Porras
V
V
Méndez Martín
J
J
D000208:Acute Disease; D000818:Animals; D001835:Body Weight; D005260:Female; D007421:Intestine, Small / Q000098:blood supply; D007511:Ischemia / Q000401:mortality* / Q000601:surgery*; D008643:Mesentery / Q000098:blood supply*; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
Influencia del peso corporal y del período de isquemia mesentérica aguda en la mortalidad de ratas sometidas a revascularización intestinal.