Two new sheep haemoglobins, one of which is replaced by haemoglobin C in anaemia.
Two new haemoglobin variants, provisionally named Hb G and Hb H, were found during a survey of 295 Welsh Mountain cross-bred sheep. Both haemoglobins appear to be beta chain variants controlled by genes allelic to those for the common forms Hb A and Hb B. Studies on an anaemic Hb AH and an Hb AG type sheep showed that Hb G, like Hb A, is replaced by Hb C in anaemia whereas Hb H, like Hb B, is not replaced.
Kilgour
L
L
AFRC Institute of Animal Physiology and Genetics Research, Babraham, Cambridge, UK.
Dixon
S C
SC
Tucker
E M
EM
D000740:Anemia / Q000097:blood*; D000818:Animals; D005260:Female; D014644:Genetic Variation; D006444:Hemoglobin C / Q000032:analysis; D006447:Hemoglobin H / Q000032:analysis; D006454:Hemoglobins / Q000032:analysis*; D007525:Isoelectric Focusing; D008297:Male; D010641:Phenotype; D012156:Reticulocytes / Q000032:analysis; D012756:Sheep / Q000097:blood*
D006454:Hemoglobins; D006444:Hemoglobin C; D006447:Hemoglobin H