title: Synthesis and activity of a novel, irreversible inhibitor of cathepsin B.
authors.affiliation: Department of Biochemistry, Queen's University of Belfast, Northern Ireland.
authors.forename: B M
authors.initials: BM
authors.lastname: Cullen
authors.forename: A
authors.initials: A
authors.lastname: McGinty
authors.forename: B
authors.initials: B
authors.lastname: Walker
authors.forename: J
authors.initials: J
authors.lastname: Nelson
authors.forename: I
authors.initials: I
authors.lastname: Halliday
authors.forename: J R
authors.initials: JR
authors.lastname: Bailie
authors.forename: G
authors.initials: G
authors.lastname: Kay
mesh_terms: D000818:Animals; D001665:Binding Sites; D001710:Biotin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D002401:Cathepsin B / Q000037:antagonists & inhibitors*; D002417:Cattle; D015853:Cysteine Proteinase Inhibitors / Q000494:pharmacology; D003978:Diazomethane / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D066298:In Vitro Techniques
chemical_list: D015853:Cysteine Proteinase Inhibitors; C024918:benzyloxycarbonylphenylalanylalanine diazomethyl ketone; C064862:biotin-phenylalanyl-alanine diazomethyl ketone; D003978:Diazomethane; D001710:Biotin; D002401:Cathepsin B