title: Treatment of choroidal melanoma: MR imaging in the assessment of radioactive plaque position.
abstract: Verification of the position of an episcleral iodine-125 gold plaque in relation to underlying choroidal melanoma is essential during early radiation therapy to ensure accurate plaque placement and thus optimum dose delivery. The authors used magnetic resonance (MR) imaging to examine 15 patients with choroidal melanoma after plaque placement to assess tumor coverage. The relationship of the plaque to the tumor was well defined in all cases, including two tumors anterior to the ora serrata. MR imaging measurements of the plaques were within 1 mm of the actual plaque sizes, while tumor measurements were within 2 mm of the preoperative ultrasound estimations of tumor dimensions. Tumors as small as 3 mm thick were readily visualized with MR imaging. Associated subretinal effusion was demonstrated in seven cases.
authors.affiliation: Department of Diagnostic Imaging, St Jude Children's Research Hospital, Memphis, TN 38101.
authors.forename: S L
authors.initials: SL
authors.lastname: Hanna
authors.forename: M A
authors.initials: MA
authors.lastname: Lemmi
authors.forename: J W
authors.initials: JW
authors.lastname: Langston
authors.forename: J
authors.initials: J
authors.lastname: Fontanesi
authors.forename: H L
authors.initials: HL
authors.lastname: Brooks
authors.forename: S
authors.initials: S
authors.lastname: Gronemeyer
mesh_terms: D000368:Aged; D001918:Brachytherapy; D002830:Choroid Neoplasms / Q000175:diagnosis / Q000532:radiotherapy*; D003287:Contrast Media; D019786:Gadolinium DTPA; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008545:Melanoma / Q000175:diagnosis / Q000532:radiotherapy*; D009942:Organometallic Compounds; D004369:Pentetic Acid
chemical_list: D003287:Contrast Media; D007457:Iodine Radioisotopes; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA