[Dose titration with Euphylong following prior determination of serum concentration in the steady state].
Euphylong is a theophylline preparation with new galenic slow-release design (micropellets in a capsule), developed for daily single-dose administration in the evening. It has been shown that the majority of patients with bronchial asthma, chronic obstructive bronchitis or emphysema who receive a single evening dose of Euphylong have a theophylline serum concentration that remains within the therapeutic range for 24 hours when the theophylline serum concentration measured at 8 a.m. under steady-state conditions is found to lie within the therapeutic range.
Schnabel
D
D
Abt. Pneumologie, Medizinische Universitätsklinik, Homburg/Saar.
von Treufels
S
S
Oellerich
M
M
Böttger
H C
HC
Sybrecht
G W
GW
D000328:Adult; D000368:Aged; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000097:blood / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D013806:Theophylline / Q000008:administration & dosage* / Q000493:pharmacokinetics
D013806:Theophylline
Untersuchungen zur Dosistitration mit Euphylong nach vorausgegangener Serumkonzentrationsbestimmung im steady state.