title: Disseminated Mycobacterium fortuitum successfully treated with combination therapy including ciprofloxacin.
abstract: We report a case of disseminated Mycobacterium fortuitum in a 76-yr-old male with no identifiable predisposing factors except chronic interstitial lung disease. Recurrent, progressive pulmonary symptoms and radiographic findings were followed by the development of multiple, culture-positive peripheral lesions. The patient responded rapidly and completely to combination therapy consisting primarily of ciprofloxacin, minocycline, and surgical drainage. Our experience supports the cautious use and further study of fluorinated quinolones for M. fortuitum infections caused by susceptible isolates.
authors.affiliation: Division of Infectious Diseases, Washington Veterans Affairs Medical Center, Washington, DC 20422.
authors.forename: D N
authors.initials: DN
authors.lastname: Burns
authors.forename: P K
authors.initials: PK
authors.lastname: Rohatgi
authors.forename: R
authors.initials: R
authors.lastname: Rosenthal
authors.forename: M
authors.initials: M
authors.lastname: Seiler
authors.forename: F M
authors.initials: FM
authors.lastname: Gordin
mesh_terms: D000368:Aged; D002939:Ciprofloxacin / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004322:Drainage; D006801:Humans; D008297:Male; D008911:Minocycline / Q000627:therapeutic use*; D009165:Mycobacterium Infections, Nontuberculous / Q000628:therapy; D013754:Tetracyclines / Q000627:therapeutic use*; D014382:Tuberculosis, Cutaneous / Q000628:therapy*; D014394:Tuberculosis, Osteoarticular / Q000628:therapy*; D014397:Tuberculosis, Pulmonary / Q000628:therapy*
chemical_list: D013754:Tetracyclines; D002939:Ciprofloxacin; D008911:Minocycline