title: Albumin adsorption on to aluminium oxide and polyurethane surfaces.
abstract: The changes in protein adsorption onto aluminium surfaces coated with different thicknesses of oxide layers were examined. The oxide layers on aluminium substrates were derived by the anodizing technique. Protein adsorption studies were conducted using 125I-labelled albumin and the amount of albumin adsorbed was estimated with the help of a gamma counter. An increase in albumin adsorption was observed on oxide layer coated aluminium surfaces. The effect of anti-Hageman factor on albumin and fibrinogen adsorption on to bare aluminium, oxide layer coated aluminium and bare polyether urethane urea surfaces was also investigated. It was observed that the presence of anti-Hageman factor increased the adsorption of albumin and fibrinogen on to all these substrates.
authors.affiliation: Biosurface Technology Division, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Poojapura, Trivandrum, India.
authors.forename: C P
authors.initials: CP
authors.lastname: Sharma
authors.forename: M C
authors.initials: MC
authors.lastname: Sunny
mesh_terms: D000327:Adsorption; D000418:Albumins; D000535:Aluminum; D000537:Aluminum Oxide; D001672:Biocompatible Materials; D005340:Fibrinogen; D008422:Materials Testing; D010087:Oxides; D011140:Polyurethanes; D013499:Surface Properties
chemical_list: D000418:Albumins; D001672:Biocompatible Materials; D010087:Oxides; D011140:Polyurethanes; D005340:Fibrinogen; D000535:Aluminum; D000537:Aluminum Oxide