A carbohydrate-rich diet not only leads to incorporation of medium-chain fatty acids (6:0-14:0) in milk triglycerides but also in each milk-phospholipid subclass.
We isolated phospholipid (PL) subclasses from milk of women in Dominica and Belize. Fatty acid (FA) compositions of PLs and total lipids were determined. In the total-lipid fraction Dominican milk showed higher relative amounts of medium-chain saturated fatty acids (MC-SAFAs; 6:0-14:0) and 22:6n-3 and lower amounts of long-chain saturated fatty acids (LC-SAFAs) and monounsaturated fatty acids (MUFAs). There was a positive relationship between the MC-SAFA content in total lipids and total PLs. Incorporation of MC-SAFAs in PLs occurred at the expense of LC-SAFAs, MUFAs, polyunsaturated fatty acids (PUFAs), and long-chain PUFAs with greater than or equal to 20 carbon atoms (LC-PUFAs greater than or equal to C20). Previous studies from Western countries revealed low amounts of MCSAFAs and high amounts of PUFAs and LC-PUFAs greater than or equal to C20 in milk PLs. Our data show that carbohydrate-rich diets give rise to incorporation of MC-SAFAs in PLs at the expense of PUFAs and LC-PUFAs greater than or equal to C20. The data are discussed in relation to the presumed origin of fat-globule membrane phospholipids.
van Beusekom
C
C
Central Laboratory for Clinical Chemistry, University Hospital Groningen, The Netherlands.
Martini
I A
IA
Rutgers
H M
HM
Boersma
E R
ER
Muskiet
F A
FA
D001531:Belize; D004040:Dietary Carbohydrates / Q000008:administration & dosage*; D005227:Fatty Acids / Q000032:analysis*; D005260:Female; D006801:Humans; D008895:Milk, Human / Q000032:analysis*; D010743:Phospholipids / Q000032:analysis*; D012044:Regression Analysis; D014280:Triglycerides / Q000032:analysis*; D014900:West Indies
D004040:Dietary Carbohydrates; D005227:Fatty Acids; D010743:Phospholipids; D014280:Triglycerides