title: Cytogenetic damage in operation theatre personnel.
abstract: The study in a group of 24 (11 anaesthetists and 13 support staff) was planned to ascertain the cytogenetic risk in a group of theatre personnel who worked in various city hospitals. Their exposure in terms of duration of service vary from 3-30 years. The control group (n = 24) consisted of people with different occupations matched for possible confounding variables. Cytogenetic risk was assessed in terms of chromosome aberration and sister chromatid exchange in 72-hour lymphocyte cultures. A significant increase in the percentage of chromosome aberration was observed. The sister chromatid exchange was double that of the baseline value in 20% of the exposed individuals. These findings indicate the possible risk of cytogenetic damage for staff working in unscavenged rooms.
authors.affiliation: Darwin College, Cambridge, UK.
authors.forename: D
authors.initials: D
authors.lastname: Natarajan
authors.forename: S T
authors.initials: ST
authors.lastname: Santhiya
mesh_terms: D000328:Adult; D000395:Air Pollutants, Occupational / Q000009:adverse effects; D000776:Anesthesiology; D000777:Anesthetics / Q000009:adverse effects; D002869:Chromosome Aberrations; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure; D008297:Male; D008505:Medical Staff, Hospital; D008875:Middle Aged; D009872:Operating Room Technicians; D009873:Operating Rooms; D012307:Risk Factors; D012854:Sister Chromatid Exchange; D013997:Time Factors
chemical_list: D000395:Air Pollutants, Occupational; D000777:Anesthetics