title: Rhinocerebral mucormycosis: management and survival after carotid occlusion.
abstract: Rhinocerebral mucormycosis is a rare but often fatal fungal infection. We present 2 patients with mucormycosis complicated by internal carotid artery thrombosis. Magnetic resonance imaging was superior to computed tomography in localizing the pathological process. Subtotal resection of devitalized tissue and intravenous amphotericin B therapy resulted in a successful outcome for both patients. Prompt recognition of this disorder by using modern diagnostic and therapeutic modalities promises to improve survival rates.
authors.affiliation: Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia.
authors.forename: S L
authors.initials: SL
authors.lastname: Galetta
authors.forename: A E
authors.initials: AE
authors.lastname: Wulc
authors.forename: H I
authors.initials: HI
authors.lastname: Goldberg
authors.forename: C W
authors.initials: CW
authors.lastname: Nichols
authors.forename: J S
authors.initials: JS
authors.lastname: Glaser
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D002340:Carotid Artery Diseases / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging; D002426:Cavernous Sinus / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D009916:Orbital Diseases / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D010254:Paranasal Sinus Diseases / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D011859:Radiography