title: [Effect of enkephalins and naloxone on the activity of the kallikrein-kinin system in experimental hemorrhagic shock].
abstract: The effect of enkephalin derivates with different receptor subtype specificity and opioid antagonist naloxone on kallikrein-kinin system was studied in anaesthetized rats exposed to 30% hemorrhage. Hemorrhage by itself caused only a slight activation of KKS. Pretreatment with naloxone induced a significant activation of KKS, which was potentiated by subsequent hemorrhage.
authors.affiliation: Institut für Pathologische Biochemie, Medizinischen Akademie Carl Gustav Carus, Dresden.
authors.forename: H
authors.initials: H
authors.lastname: Kühne
authors.forename: J
authors.initials: J
authors.lastname: Grässler
authors.forename: M
authors.initials: M
authors.lastname: Steinke
authors.forename: V D
authors.initials: VD
authors.lastname: Slepuschkin
authors.forename: G K
authors.initials: GK
authors.lastname: Zoloev
mesh_terms: D000818:Animals; D004745:Enkephalins / Q000494:pharmacology*; D007610:Kallikreins / Q000378:metabolism*; D007705:Kinins / Q000378:metabolism*; D008297:Male; D009270:Naloxone / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D012771:Shock, Hemorrhagic / Q000378:metabolism*
chemical_list: D004745:Enkephalins; D007705:Kinins; D009270:Naloxone; D007610:Kallikreins
vernacular_title: Einfluss von Enkephalinen und Naloxon auf die Aktivierung des Kallikrein-Kinin-Systems im experimentellen hämorrhagischen Schock.