title: [A case of a gastric cancer patient with high serum pepsinogen levels at relapse].
abstract: A rare case of a 68-year-old female cancer patient with an extremely high serum level of pepsinogens (PG) at relapse is presented. She had stage 3 Borrmann 3 type gastric cancer which was a poorly differentiated adenocarcinoma. Her postoperative serum PG levels had been within normal limits (23.0 ng/ml for PG-I and 3.2 ng/ml for PG-II), but at the time of the peritoneal relapse they were 5,630 ng/ml and 3,380 ng/ml, respectively. After was chemotherapy initiated, her serum PG levels decreased in parallel with an improvement of her clinical status. Immunohistochemical examination with monoclonal antibodies revealed PG-I and PG-II production in the primary and the metastatic lesions.
authors.affiliation: Dept. of Radiology, Ehime Univ. Med. School.
authors.forename: Y
authors.initials: Y
authors.lastname: Kimura
authors.forename: T
authors.initials: T
authors.lastname: Fujii
authors.forename: N
authors.initials: N
authors.lastname: Miyagawa
authors.forename: S
authors.initials: S
authors.lastname: Tanada
authors.forename: K
authors.initials: K
authors.lastname: Hamamoto
authors.forename: S
authors.initials: S
authors.lastname: Kimura
mesh_terms: D000230:Adenocarcinoma / Q000201:enzymology* / Q000473:pathology / Q000601:surgery; D000368:Aged; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D010435:Pepsinogens / Q000097:blood*; D013274:Stomach Neoplasms / Q000201:enzymology* / Q000473:pathology / Q000601:surgery
chemical_list: D010435:Pepsinogens