[The use of blood plasma with elevated titers of antibodies to Re-chemotype glycolipid in peritonitis].
The article analyzes the possibility of immunotherapy of septic complications in cases of peritonitis caused by gram-negative bacteria. A strictly inverse correlation between the severity of intoxication and the level of antibodies to glycolipid Re in blood serum has been established. About 5% of healthy nonimmunized donors have elevated Re-antibody titers (1:128 and higher) in their blood plasma. Screening of blood preparations from more than 1000 donors permitted the creation of the blood plasma bank used for the treatment of peritonitis patients. Immunotherapy of such patients has made it possible to decrease almost two-fold the death rate and to reduce the severity and duration of the intoxication syndrome in patients, as well as to improve the results of the treatment of peritonitis.
Apollonin
A V
AV
Rudik
A A
AA
Kropacheva
E I
EI
Likhoded
V G
VG
D000208:Acute Disease; D000906:Antibodies / Q000097:blood / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000276:immunology / Q000628:therapy; D001782:Blood Donors; D001803:Blood Transfusion; D003131:Combined Modality Therapy; D006017:Glycolipids / Q000097:blood / Q000276:immunology*; D006090:Gram-Negative Bacteria; D006386:Hemagglutination Tests; D006801:Humans; D010538:Peritonitis / Q000276:immunology / Q000628:therapy*; D010949:Plasma / Q000032:analysis / Q000276:immunology*; D011183:Postoperative Complications / Q000628:therapy
D000906:Antibodies; D006017:Glycolipids; C055264:Re-glycolipid
Primenenie plazmy krovi s povyshennymi titrami antitel k glikolipidu Re-khemotipa pri peritonitakh.