Allergic nephropathy associated with ciprofloxacin.
We report a case of ciprofloxacin-related allergic tubulointerstitial nephritis, which manifested as nonoliguric renal failure, eosinophilia, and eosinophiluria. Our patient responded to discontinuation of ciprofloxacin therapy and oral administration of a brief course of corticosteroids. Although rare, allergic tubulointerstitial nephritis apparently can be caused by ciprofloxacin therapy. Clinicians should be aware of this entity.
Rastogi
S
S
Division of Nephrology and Internal Medicine, Mayo Clinic, Rochester, MN 55905.
Atkinson
J L
JL
McCarthy
J T
JT
D058186:Acute Kidney Injury / Q000139:chemically induced; D000368:Aged; D002939:Ciprofloxacin / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology*; D004802:Eosinophilia / Q000139:chemically induced; D006801:Humans; D008297:Male; D009395:Nephritis, Interstitial / Q000139:chemically induced*
D002939:Ciprofloxacin