title: A new variant of the Es-4 locus in the rat.
abstract: A new variant of kidney esterase in the DK/Nac rat strain is reported. The new esterase was tentatively named ES-4C determined by a third allele of the Es-4 locus of Linkage Group V (LGV). Strain distribution was surveyed using 17 inbred strains, but no strain except for the DK/Nac strain possessed the ES-4C type. Although we surveyed outbred stocks (Jcl: Wistar and Jcl: SD) we could not find rats carrying the ES-4C type. Genetic analysis of the ES-4C type was carried out using mating experiments between DK/Nac and BUF/Nac (ES-4B). The results indicated that the new variant was controlled by the Es-4 locus and it was named the Es-4c allele.
authors.affiliation: Department of Genetics, Central Institute for Experimental Animals, Kawasaki, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Katoh
authors.forename: S
authors.initials: S
authors.lastname: Utsu
authors.forename: S
authors.initials: S
authors.lastname: Wakana
authors.forename: Q F
authors.initials: QF
authors.lastname: Li
mesh_terms: D000483:Alleles; D000818:Animals; D002874:Chromosome Mapping; D004950:Esterases / Q000235:genetics* / Q000378:metabolism; D008040:Genetic Linkage; D014644:Genetic Variation; D007668:Kidney / Q000201:enzymology*; D010641:Phenotype; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D004950:Esterases