[Glomerular erythrocytes, albuminuria, glycosaminoglycans and exposure to hydrocarbons].
As part of a study on the possible nephrotoxicity of hydrocarbons, the urinary erythrocyte concentration and the percentage of glomerular erythrocytes were assessed. Albumin excretion rate, glycosaminoglycan and retinol-binding protein concentration, and N-acetyl-beta-glucosaminidase activity were measured simultaneously. The results show that the erythrocyte concentration and the percentage of glomerular erythrocytes tend to increase with hydrocarbon exposure, and that a nephrotoxic effect of occupational hydrocarbon exposure deserves consideration.
Hotz
P
P
Institut universitaire de médecine et hygiène du travail, Division d'endocrinologie et biochimie clinique, Faculté de médecine, Lausanne.
Pilliod
J
J
Bernard
A
A
Rey
F
F
Boillat
M A
MA
D000118:Acetylglucosaminidase / Q000652:urine; D000293:Adolescent; D000328:Adult; D000419:Albuminuria / Q000175:diagnosis*; D004781:Environmental Exposure; D004912:Erythrocytes; D006025:Glycosaminoglycans / Q000652:urine; D006801:Humans; D006846:Hydrocarbons, Halogenated / Q000633:toxicity*; D007678:Kidney Glomerulus / Q000166:cytology / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D011890:Railroads; D012177:Retinol-Binding Proteins / Q000652:urine; D014556:Urine / Q000166:cytology*
D006025:Glycosaminoglycans; D006846:Hydrocarbons, Halogenated; D012177:Retinol-Binding Proteins; D000118:Acetylglucosaminidase
Erythrocytes glomérulaires, albuminurie, glycosaminoglycanes et exposition aux hydrocarbures.