title: Examination of the effect of histodil prophylaxis in infarction patients with inhibited haemostasis.
abstract: The initiation of anticoagulants and drugs with platelet aggregation inhibiting properties is justified for the treatment of myocardial infarction in a great number of conditions. The well-known complications of this therapy are gastro-intestinal haemorrhage and the concomitant discomfort. In the period from 1983 to 1986 Histodil was given as adjuvant to therapy for infarction patients with ulcer, gastro-intestinal haemorrhage, hyperacidity or other epigastric burn-pain syndrome in history. The patients treated at our department between 1979-82 had not received Histodil for this purpose. According to the retrospective examinations the preventive effect of Histodil prophylaxis was 100%. Therefore the drug may be recommended to myocardial infarction patients in whom the inhibition of haemostasis means an increased risk of gastro-intestinal alteration.
authors.affiliation: Second Department of Medicine, Municipal Ujpesti Hospital, Outpatient Clinic, Budapest.
authors.forename: V
authors.initials: V
authors.lastname: Nagy
authors.forename: L
authors.initials: L
authors.lastname: Csürös
authors.forename: M
authors.initials: M
authors.lastname: Iskum
mesh_terms: D015746:Abdominal Pain / Q000517:prevention & control*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000009:adverse effects* / Q000627:therapeutic use; D002927:Cimetidine / Q000627:therapeutic use*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy; D012189:Retrospective Studies
chemical_list: D000925:Anticoagulants; D002927:Cimetidine