title: Sex-linked determinants for IgM?
abstract: Evidence for a sex-linked determinant of immunoglobulin M levels was sought using correlational and commingling analyses in a sample of 174 randomly selected nuclear families. While mean IgM levels in females were approximately 25% higher than that in males, the pattern of familial correlations did not follow the expectations under a sex-linked model, and there was no commingling in the distribution of IgM levels as expected when a trait is under the influence of a major gene.
authors.affiliation: Department of Psychology, University of Minnesota, Minneapolis.
authors.forename: M
authors.initials: M
authors.lastname: McGue
authors.forename: I B
authors.initials: IB
authors.lastname: Borecki
authors.forename: J W
authors.initials: JW
authors.lastname: Gerrard
authors.forename: D C
authors.initials: DC
authors.lastname: Rao
mesh_terms: D002170:Canada; D003198:Computer Simulation; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D007075:Immunoglobulin M / Q000235:genetics*; D008297:Male; D014960:X Chromosome
chemical_list: D007075:Immunoglobulin M