title: The influence of inner ear melanin on susceptibility to TTS in humans.
abstract: In order to investigate the function of the inner ear melanin, the relationship between skin pigmentation and noise-induced temporary hearing loss (TTS) was studied. Forty-four normal-hearing Caucasian subjects were divided into three groups according to their sun sensitivity. Hearing thresholds before and after exposure were ascertained with a computerized sweep frequency audiometer in the frequency range 2-8 kHz. The noise exposure consisted of a 1/3-octave band-filtered noise with a centre frequency of 2 kHz at 105 dB SPL for 10 min. The mean TTS in the frequency range 2-8 kHz showed statistically significant differences between the three groups, i.e. the most pigmented subjects developed least TTS, and the least pigmented subjects most TTS.
authors.affiliation: Department of Audiology, Sahlgrenska Sjukhuset, Göteborg, Sweden.
authors.forename: M L
authors.initials: ML
authors.lastname: Barrenäs
authors.forename: F
authors.initials: F
authors.lastname: Lindgren
mesh_terms: D000293:Adolescent; D001299:Audiometry; D001309:Auditory Threshold / Q000502:physiology; D007758:Ear, Inner / Q000502:physiology*; D006317:Hearing Loss, Noise-Induced / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008297:Male; D008543:Melanins / Q000502:physiology*; D008544:Melanocytes / Q000502:physiology; D012880:Skin Pigmentation / Q000502:physiology*; D013997:Time Factors
chemical_list: D008543:Melanins