[The results of the radiation treatment of cervical cancer using low, sensitizing doses of radiation].
Combined radiation treatment for cervical cancer is associated with radiation injury to the intestine, bladder, hemopoietic system and suppression of T-system, nonspecific immunity and thyroid function. Modified gamma-ray teletherapy was suggested which included low-dose (0.1 Gy) sensitizing irradiation of tumor and zones of regional dissemination prior to delivering therapeutic dose (1.9 Gy). The procedure assured lower incidence of radiation-induced reactions and complications, leukopenia and T-lymphocyte function suppression, stimulated nonspecific resistance and thyrotropic function of the pituitary, and provided normal function of the thyroid. As a result, five-year survival rate in patients with stage III cancer increased by 14%.
Iakimova
T P
TP
Gerinshteĭn
I G
IG
Pashchenko
N S
NS
Lozinskaia
I N
IN
Kozyreva
T V
TV
Serebriakov
A M
AM
D000328:Adult; D000368:Aged; D001918:Brachytherapy; D003037:Cobalt Radioisotopes / Q000008:administration & dosage; D005260:Female; D005720:Gamma Rays / Q000627:therapeutic use; D006801:Humans; D007111:Immunity, Cellular / Q000528:radiation effects; D007113:Immunity, Innate / Q000528:radiation effects; D008875:Middle Aged; D011832:Radiation Injuries / Q000453:epidemiology; D011867:Radioisotope Teletherapy; D011879:Radiotherapy Dosage; D013961:Thyroid Gland / Q000528:radiation effects; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000276:immunology / Q000401:mortality / Q000532:radiotherapy*
D003037:Cobalt Radioisotopes
Rezul'taty luchevogo lecheniia raka sheĭki matki s ispol'zovaniem malykh sensibiliziruiushchikh doz radiatsii.