title: [Destabilization of erythrocyte lipid structures in blood coagulation].
abstract: Main parameters of lipid complex were studied in erythrocytes of whole blood and of the blood containing anticoagulant. Initial steps of blood coagulation involved activation of erythrocyte endogenous phospholipase A, which led to destabilization of erythrocyte lipid structures as a result of an increase in concentration of free fatty acids, accumulation of lysophospholipids as well as of alterations in microviscosity of erythrocyte membranes.
authors.forename: V I
authors.initials: VI
authors.lastname: Rubin
authors.forename: G A
authors.initials: GA
authors.lastname: Bezrukova
mesh_terms: D001777:Blood Coagulation; D002784:Cholesterol / Q000097:blood; D004789:Enzyme Activation; D004910:Erythrocyte Membrane / Q000201:enzymology / Q000378:metabolism*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D006801:Humans; D008563:Membrane Lipids / Q000097:blood*; D010741:Phospholipases A / Q000097:blood; D010743:Phospholipids / Q000097:blood
chemical_list: D005230:Fatty Acids, Nonesterified; D008563:Membrane Lipids; D010743:Phospholipids; D002784:Cholesterol; D010741:Phospholipases A
vernacular_title: Destabilizatsiia lipidnykh struktur éritrotsitov pri svertyvanii krovi.