[A long-term follow-up study of intra-arterial infusion chemotherapy in locally advanced breast cancer].
Long-term follow-up results were reported for 61 patients with locally advanced breast cancer treated by intraarterial infusion chemotherapy (IA), compared with those for 96 patients who received no such treatment. The results were as follows. (1) The response rate of the primary lesions to IA was 53.6%, and the post-surgical survival of responders (CR, PR) was significantly better than those of non-responders (NC). (2) Excellent loco-regional control was also achieved in the IA-group. The local recurrence rate was only 16.2%. (3) However, there was no difference between survival rates of each group. The author confirmed that IA was an effective initial treatment for locally advanced breast cancer in terms of loco-regional control, but definite conclusions can be made only after randomized study.
Takatsuka
Y
Y
Dept. of Surgery, Osaka National Hospital.
Okamura
Y
Y
Kawahara
T
T
Yayoi
E
E
Miyauchi
K
K
Shiba
E
E
D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007261:Infusions, Intra-Arterial; D009367:Neoplasm Staging; D011379:Prognosis; D015996:Survival Rate; D013629:Tamoxifen / Q000008:administration & dosage
D000970:Antineoplastic Agents; D013629:Tamoxifen