Decreased necessity for dialysis with loop diuretic therapy in hemolytic uremic syndrome.
High dose loop diuretic therapy was administered at time of admission to hospital or at time of diagnosis to 54 patients with childhood hemolytic uremic syndrome. Forty-one patients maintained a diuresis sufficient to avoid the necessity for dialysis. When compared to an earlier time period the dialysis rate fell from 82% to 24% with furosemide therapy. Though a change in disease severity may explain the decrease in necessity for dialysis, a salutary effect of furosemide therapy may also be responsible.
Rousseau
E
E
Department of Pediatrics, University of Montreal, Hôpital Ste-Justine, Quebec, Canada.
Blais
N
N
O'Regan
S
S
D001806:Blood Urea Nitrogen; D002675:Child, Preschool; D003404:Creatinine / Q000378:metabolism; D005665:Furosemide / Q000627:therapeutic use*; D006454:Hemoglobins; D006463:Hemolytic-Uremic Syndrome / Q000188:drug therapy* / Q000628:therapy; D006801:Humans; D007262:Infusions, Intravenous; D010530:Peritoneal Dialysis; D010976:Platelet Count; D012189:Retrospective Studies
D006454:Hemoglobins; D005665:Furosemide; D003404:Creatinine