[Effects of stress on colon in the canine].
In order to clarify the effects of stress on the colon, functions of the colon in conscious dogs were examined by using strain gauge force transducers and periodical X-ray pictures. Immediately after loading the stress, the motility of colon increased, while 2 weeks after loading the stress the motility of the colon had decreased. Under these circumstances all dogs with dysfunctions of right colon had diarrhea, while dogs with dysfunctions of left colon had no diarrhea. This stress model did not result in the formation of ulcers and dogs had intestinal dysfunction and diarrhea. Therefore, this stress model may be an appropriate method in which to study diarrhea and irritable bowel syndrome.
Ochiai
T
T
First Department of Surgery, Juntendo University School of Medicine, Tokyo.
D000818:Animals; D003106:Colon / Q000503:physiopathology*; D003967:Diarrhea / Q000209:etiology; D004285:Dogs; D005769:Gastrointestinal Motility; D013312:Stress, Physiological / Q000503:physiopathology*