title: Three-dimensional photon radiotherapy planning for laryngeal and hypopharyngeal tumours.
abstract: Three-dimensional absorbed dose distributions have been computed for high-energy photon radiation therapy of laryngeal and hypopharyngeal cancers, using a coaxial pair of opposing lateral beams in fixed positions. Treatment plans obtained under various conditions of irradiation are analyzed and compared for a cobalt-60 gamma unit (GAMMATRON S80, Siemens), photon beams from a 6 MV (CLINAC 1800, VARIAN), an 8 MV (SATURNE, CGR) and a 15 MV (MEVATRON 77, Siemens) linear accelerator. Using open fields a somewhat non-uniform and partly insufficient dose in target volume of interest is obtained with all treatment units if sufficient protection of the spinal cord is provided. The x-ray plans are somewhat superior to the cobalt-60 ones. Depending on the quantum energy and wedge isodose angle, wedging only slightly improves or sometimes moderately decreases the homogeneity of the dose in the target volume. According to these small and/or controversial effects of wedges their application seems unnecessary and/or non-convenient. Simulations show that extreme care is needed in positioning the isocentre: an accuracy of +/- 3 mm is required in the median sagittal plane.
authors.affiliation: Department of Radiology, Albert Szent-Györgyi Medical University, Szeged, Hungary.
authors.forename: O
authors.initials: O
authors.lastname: Esik
authors.forename: W
authors.initials: W
authors.lastname: Schlegel
authors.forename: J
authors.initials: J
authors.lastname: Doll
authors.forename: G
authors.initials: G
authors.lastname: Németh
authors.forename: W J
authors.initials: WJ
authors.lastname: Lorenz
mesh_terms: D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D005720:Gamma Rays; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000532:radiotherapy*; D007822:Laryngeal Neoplasms / Q000532:radiotherapy*; D010610:Pharyngeal Neoplasms / Q000532:radiotherapy*; D011829:Radiation Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D011881:Radiotherapy, Computer-Assisted; D014965:X-Rays
chemical_list: D003037:Cobalt Radioisotopes