The effects of selective cytochrome P-450 inducing agents on trimethadione metabolism as an indicator of hepatic drug-oxidizing capacity in rats.
Tanaka
E
E
Institute of Community Medicine, University of Tsukuba, Ibaraki, Japan.
Etoh
H
H
Misawa
S
S
D000818:Animals; D001140:Aroclors / Q000494:pharmacology; D001571:Benzoflavones / Q000494:pharmacology; D020111:Chlorodiphenyl (54% Chlorine); D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis*; D003907:Dexamethasone / Q000494:pharmacology; D004790:Enzyme Induction / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology; D010080:Oxazoles / Q000378:metabolism*; D010634:Phenobarbital / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D012451:Safrole / Q000494:pharmacology; D014293:Trimethadione / Q000378:metabolism*; D019324:beta-Naphthoflavone
D001140:Aroclors; D001571:Benzoflavones; D010080:Oxazoles; D020111:Chlorodiphenyl (54% Chlorine); D008748:Methylcholanthrene; D019324:beta-Naphthoflavone; D003907:Dexamethasone; D003577:Cytochrome P-450 Enzyme System; D014293:Trimethadione; D012451:Safrole; C015959:isosafrole; D010634:Phenobarbital