[Etiologic and biologic heterogeneity of growth hormone deficiency: significance of neuro-secretory dysfunction].
The pharmacological tests and the 24 hours secretion permitted to accept 96 cases among a group of 301 children with short stature. The aetiologic parameters are numerous. There are too a great heterogeneity for the diagnostic criteria of GH deficiency: severe or partial, concordant or discordant between the two biologic methods with a new variety called neuro-secretory dysfunction with normal pharmacological tests and poor endogenous secretion.
Battin
J
J
Clinique universitaire de Pédiatrie et Génétique médicale, Hôpital des Enfants, Bordeaux.
D000293:Adolescent; D002648:Child; D002940:Circadian Rhythm; D005260:Female; D006130:Growth Disorders / Q000097:blood* / Q000175:diagnosis / Q000209:etiology; D013006:Growth Hormone / Q000097:blood / Q000172:deficiency*; D006801:Humans; D008297:Male; D009489:Neurosecretion
D013006:Growth Hormone
Hétérogénéité étiologique et biologique des déficits en hormone de croissance: intérêt de la dysfonction neuro-sécrétoire.