Possible intramuscular midazolam-associated cardiorespiratory arrest and death.
Midazolam hydrochloride is commonly used for dental or endoscopic procedures. Although generally consisted safe when given intramuscularly, intravenous administration is known to cause respiratory and cardiovascular depression. This report describes the first published case of cardiorespiratory arrest and death associated with intramuscular administration of midazolam. Information regarding midazolam use is reviewed to provide recommendation for safe administration.
Taylor
J W
JW
Department of Clinical Pharmacy Practice, University of Mississippi, Jackson 39216.
Simon
K B
KB
D006323:Heart Arrest / Q000139:chemically induced*; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008874:Midazolam / Q000008:administration & dosage / Q000009:adverse effects*; D008875:Middle Aged; D012140:Respiratory Tract Diseases / Q000139:chemically induced*
D008874:Midazolam