title: [Evaluation of the development of immunologic response in patients with cutaneous leishmaniasis].
abstract: In this study we present epidemiological and immunological data about cutaneous Leishmaniasis in Panama, in an area where recurrence occurs in 65% of the cases evaluated. The development of the cellular immune response, during clinical evolution of primary and recurrent cases, indicates that initial stimulation index (SI) less than 3 are observed in recurrent cases, while this level is higher than 3 in primary cases. The humoral immune response is related only with the time of clinical evolution. We point out the importance of looking at the population of T lymphocytes quantitatively, as well as looking at the levels of lymphokines, in order to explain the differences that we observed in the cellular immune response.
authors.affiliation: Centro de Investigación y Diagnóstico de Enfermedades Parasitarias, Facultad de Medicina, Universidad de Panamá.
authors.forename: P F
authors.initials: PF
authors.lastname: de Carreira
authors.forename: M O
authors.initials: MO
authors.lastname: Suárez
authors.forename: J M
authors.initials: JM
authors.lastname: Pascale
authors.forename: O E
authors.initials: OE
authors.lastname: Sousa
mesh_terms: D000293:Adolescent; D000917:Antibody Formation; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007223:Infant; D007896:Leishmaniasis / Q000097:blood / Q000276:immunology*; D008297:Male; D011446:Prospective Studies; D012008:Recurrence
vernacular_title: Evaluación del desarrollo de la respuesta inmunológica en pacientes con Leishmaniasis cutánea.