[Fractionated radiation and thermal-radiation actions on transplantable tumors].
The paper is concerned with the results of fractionated thermal-radiation action on Brown-Pearce tumor in rabbits, sarcoma-37 (C-37) and Lewis carcinoma (LLC) in outbred and hybrid F1 (C57B1/6 x CBA) mice. Rabbit tumors were subjected to hyperthermia on UHF Plot units 4 h after irradiation, and in mice with a water-bath directly before irradiation. The frequency of Brown-Pearce tumor regression was increased as a result of hyperthermia in 4 h. The comparison of the effectiveness of fractionated radiation or thermal-radiation action on murine tumors (2 of 3 fractions for 4 days) indicated different type changes of the value of the coefficient of thermal enhancement of hyperthermia. For C-37 it was decreased with an increase in the number of fractions, for LLC it was increased, probably as a result of reoxygenation and high radiosensitivity of C-37.
Kurpeshev
O K
OK
Isaev
I G
IG
Konopliannikov
A G
AG
Lebedeva
T V
TV
D000818:Animals; D002284:Carcinoma, Brown-Pearce / Q000532:radiotherapy; D003131:Combined Modality Therapy; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006979:Hyperthermia, Induced; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000532:radiotherapy*; D011817:Rabbits; D012074:Remission Induction; D013997:Time Factors
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