title: Mutual effect of glucose and glutamine on their utilization by tumour cells.
abstract: Interactions between glucose and glutamine metabolisms have been studied in a line of Ehrlich ascites tumour cells and the results obtained are compared with those recently published for ascites Lettré cells. In contrast with Lettré cells, in the less malignant line used in this work, glucose did not modify glutaminolytic flux and glutamine changed the rate of glucose consumption. It is concluded that the biochemical behaviour of the cells could be correlated to the degree of malignancy.
authors.affiliation: Departamento de Bioquimica, Biologia Molecular y Quimica Orgánica, Facultad de Ciencias, Universidad de Málaga, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Luque
authors.forename: S
authors.initials: S
authors.lastname: Paredes
authors.forename: J A
authors.initials: JA
authors.lastname: Segura
authors.forename: I
authors.initials: I
authors.lastname: Núñez de Castro
authors.forename: M A
authors.initials: MA
authors.lastname: Medina
mesh_terms: D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism*; D002455:Cell Division; D005260:Female; D005947:Glucose / Q000378:metabolism* / Q000494:pharmacology; D005973:Glutamine / Q000378:metabolism* / Q000494:pharmacology; D006019:Glycolysis / Q000187:drug effects; D051379:Mice; D014407:Tumor Cells, Cultured
chemical_list: D005973:Glutamine; D005947:Glucose