The carcinogenic potential of cocaine.
Analysis of cocaine by CASE, an expert system, results in the prediction that cocaine is a rodent carcinogen. In view of the widespread exposure to cocaine this is cause for alarm, especially as in utero exposure has been widely documented and the developing human fetus is at an increased risk of transplacental cancer induction.
Rosenkranz
H S
HS
Department of Environmental Health Sciences, Case Western Reserve University, School of Medicine, Cleveland Ohio 44106.
Klopman
G
G
D000818:Animals; D002273:Carcinogens; D003042:Cocaine / Q000633:toxicity*; D004054:Diethylstilbestrol / Q000633:toxicity; D005260:Female; D008297:Male; D051379:Mice; D008962:Models, Theoretical; D015394:Molecular Structure; D051381:Rats; D013805:Theobromine / Q000633:toxicity
D002273:Carcinogens; D004054:Diethylstilbestrol; D003042:Cocaine; D013805:Theobromine