title: [Good response to azidothymidine in 3 patients with vacuolar myelopathy].
abstract: We report 3 drug abusers with human immunodeficiency virus (HIV) infection who had presented with myelopathic symptoms. A diagnosis of vacuolar myelopathy associated with HIV was made. The patients had a favorable response to azidothymidine. They were followed up as outpatients, and they showed a significant clinical improvement within 1-3 months of therapy. They remained stable 11 months afterwards. The patients with this type of disease may benefit from azidothymidine therapy.
authors.affiliation: Unidad de Enfermedades infecciosas, Hospital Nuestra Señora de Aránzazu, San Sebastián.
authors.forename: M A
authors.initials: MA
authors.lastname: von Wichmann
authors.forename: J A
authors.initials: JA
authors.lastname: Iribarren
authors.forename: J
authors.initials: J
authors.lastname: Arrizabalaga
authors.forename: P
authors.initials: P
authors.lastname: Bernardo
authors.forename: C
authors.initials: C
authors.lastname: Garde
authors.forename: F J
authors.initials: FJ
authors.lastname: Rodríguez-Arrondo
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D013118:Spinal Cord Diseases / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D014617:Vacuoles; D015215:Zidovudine / Q000627:therapeutic use*
chemical_list: D015215:Zidovudine
vernacular_title: Buena respuesta a azidotimidina en tres pacientes con mielopatía vacuolar.