[Comparison of fluconazole and ketoconazole in the therapy of vaginal candidiasis by administration in two different oral doses].
The authors examined 20 patients affected by vaginal candidiasis and evaluated the efficacy and tolerability of treatment with Fluconazole in comparison with Ketoconazole, using two different doses of oral administration: Fluconazole, 150 mg in a single dose; Ketoconazole, 400 mg/die for 5 days. There were no significant differences in results; adverse effects were insignificant and the level of efficacy, which was the same in both cases, was high. In conclusion, both molecules are confirmed to be efficacious, although patients showed a preference for the single dose and for only one day of therapy.
Bottino
G
G
USL n. 35, Ospedale Civile di Giaveno.
Menna
C
C
D002181:Candidiasis, Vulvovaginal / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation; D005260:Female; D015725:Fluconazole / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007654:Ketoconazole / Q000008:administration & dosage / Q000627:therapeutic use*
D015725:Fluconazole; D007654:Ketoconazole
Confronto tra Fluconazolo e Ketoconazolo nella terapia orale della candidosi vaginale in due differenti modalità di somministrazione.