Intimal protection of bypass-veins during intraoperative storage in blood or Euro-Collins-solution: the role of medium, temperature, and time.
The patency-rate of venous bypasses depends - beside other important factors - upon the integrity of the transplanted vessel, especially on the condition of the tunica intima. Under this aspect we examined by light microscopy a total of over 1100 slices of human as well as animal vein-segments which had been stored in arterial heparinized blood or Euro-Collins-Solution at 4 degrees C, 20 degrees C and 37 degrees C up to 90 minutes. The results show that veins should be used immediately after harvesting. If intraoperative storage is necessary blood at a temperature between 20 degrees C and 37 degrees C is the better medium for storage periods up to 90 minutes.
Wagner
R
R
Department of Surgery, University Hospital, Frankfurt, FRG.
D000818:Animals; D001769:Blood; D003470:Culture Media; D004730:Endothelium, Vascular / Q000473:pathology*; D005260:Female; D006801:Humans; D006982:Hypertonic Solutions; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D009926:Organ Preservation; D051381:Rats; D012501:Saphenous Vein / Q000637:transplantation*; D013696:Temperature; D013997:Time Factors; D014654:Vascular Patency; D014682:Vena Cava, Inferior / Q000637:transplantation*
D003470:Culture Media; C037096:Euro-Collins' solution; D006982:Hypertonic Solutions