title: Aortic valve decalcification.
abstract: Ultrasonic decalcification of the aortic valve was performed in 22 elderly patients with critical aortic stenosis (aortic valve areas less than 0.8 cm2) as an alternative to prosthetic valve replacement. All of the patients had symptoms. The mean New York Heart Association class was 3.3 +/- 0.9. Adequate decalcification with restoration of leaflet mobility was achieved in all patients, including seven with bicuspid aortic valves. Leaflet perforation occurred and was successfully repaired in five patients. Ten patients underwent concomitant myocardial revascularization. There were two operative deaths (9%) and three late deaths. Echocardiograms were obtained preoperatively, postoperatively, and at 6 months. The mean aortic valve area increased significantly from 0.72 +/- 0.17 to 1.42 +/- 0.31 cm2 (p less than 0.001) and the peak gradient decreased from 74 +/- 34 to 25 +/- 13 mm Hg (p less than 0.001). At 6 months the aortic valve area (1.29 +/- 0.48 cm2) and peak gradient (31 +/- 12 mm Hg) continued to be significantly better than the preoperative measurements (p less than 0.001), but the 6-month aortic valve area was slightly decreased and the gradient increased when compared with the immediate postoperative values (p less than 0.02). The prevalence of mild to moderate aortic insufficiency increased from 50% of the patients preoperatively to 87% at 6 months (p less than 0.05). Two patients subsequently required aortic valve replacement for restenosis and aortic insufficiency. Ultrasonic decalcification is effective in relieving aortic stenosis, but subsequent restenosis and insufficiency may limit its application.
authors.affiliation: Department of Surgery, St. Louis University Medical Center, Mo. 63110-0250.
authors.forename: L R
authors.initials: LR
authors.lastname: McBride
authors.forename: K S
authors.initials: KS
authors.lastname: Naunheim
authors.forename: A C
authors.initials: AC
authors.lastname: Fiore
authors.forename: H H
authors.initials: HH
authors.lastname: Harris
authors.forename: V L
authors.initials: VL
authors.lastname: Willman
authors.forename: G C
authors.initials: GC
authors.lastname: Kaiser
authors.forename: D G
authors.initials: DG
authors.lastname: Pennington
authors.forename: A J
authors.initials: AJ
authors.lastname: Labovitz
authors.forename: H B
authors.initials: HB
authors.lastname: Barner
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001021:Aortic Valve / Q000503:physiopathology / Q000601:surgery; D001022:Aortic Valve Insufficiency / Q000209:etiology; D001024:Aortic Valve Stenosis / Q000503:physiopathology / Q000601:surgery*; D002114:Calcinosis / Q000601:surgery*; D004452:Echocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D013396:Suction / Q000295:instrumentation; D014464:Ultrasonic Therapy / Q000295:instrumentation