title: Recognition of the Ek1Ek1 homozygote for plasma cholinesterase.
abstract: A family is reported in which the propositus was found to be sensitive to suxamethonium. Both parents were heterozygote each having genotype Ea1Ek1. The sibling of the propositus had the most common phenotype as defined by dibucaine, fluoride and RO2 numbers. Genetic analysis, however, indicated that this sibling must be an Ek1Ek1 homozygote.
authors.affiliation: Department of Environmental Science, Polytechnic South West, Plymouth, UK.
authors.forename: M
authors.initials: M
authors.lastname: Whittaker
authors.forename: J J
authors.initials: JJ
authors.lastname: Britten
mesh_terms: D000328:Adult; D000368:Aged; D002802:Cholinesterases / Q000235:genetics*; D003992:Dibucaine; D005260:Female; D005838:Genotype; D006720:Homozygote; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D000644:Quaternary Ammonium Compounds; D012969:Sodium Fluoride
chemical_list: D000644:Quaternary Ammonium Compounds; C006266:Ro 20683; D012969:Sodium Fluoride; D002802:Cholinesterases; D003992:Dibucaine