[Is sodium salicylate suitable as a protective agent in the analgesic-induced asthma syndrome?].
The protective effect of NaS in analgetic-induced asthma (AIA) was investigated in patients with AIA. In none of the patients was the asthmatic reaction to acetylsalicylic acid (ASS) completely inhibited by the oral administration of NaS. In a single patient, an intolerance reaction occurred after oral ingestion of the substance. In several patients, induction of tolerance towards acetylsalicyclic acid was facilitated after prior ingestion of NaS.
Schäufele
A
A
Hochgebirgsklinik Davos-Wolfgang, Schweiz.
Schmitz-Schumann
M
M
Virchow
J C
JC
Menz
G
G
Virchow
C
C
D000328:Adult; D000368:Aged; D001241:Aspirin; D001249:Asthma / Q000517:prevention & control*; D001985:Bronchial Provocation Tests / Q000379:methods*; D004342:Drug Hypersensitivity / Q000517:prevention & control*; D005260:Female; D005541:Forced Expiratory Volume / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D011292:Premedication; D012980:Sodium Salicylate / Q000008:administration & dosage*
D001241:Aspirin; D012980:Sodium Salicylate
Eignet sich Natriumsalizylat (NaS) als Protektivum beim Analgetika-Asthma-Syndrom (AIA)?