title: Clastogenic effects of cesium chloride on mouse bone marrow cells in vivo.
abstract: Clastogenic effects of cesium chloride (CsCl) on mouse bone marrow cells in vivo following oral administration were studied after 24 h. The incidence of chromosome aberrations increased linearly with increasing concentrations of the chemical from 1/20th to 1/5th of the LD50. The frequency of cell division was also enhanced by the lower doses but higher doses were mitostatic. This report is the first on the clastogenicity of cesium on animals.
authors.affiliation: Department of Botany, University of Calcutta, India.
authors.forename: A
authors.initials: A
authors.lastname: Ghosh
authors.forename: A
authors.initials: A
authors.lastname: Sharma
authors.forename: G
authors.initials: G
authors.lastname: Talukder
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001853:Bone Marrow / Q000187:drug effects; D001854:Bone Marrow Cells; D002586:Cesium / Q000008:administration & dosage / Q000633:toxicity*; D002712:Chlorides; D002869:Chromosome Aberrations; D005260:Female; D051379:Mice; D008938:Mitosis / Q000187:drug effects*; D008940:Mitotic Index; D009153:Mutagens
chemical_list: D002712:Chlorides; D009153:Mutagens; D002586:Cesium; C028019:cesium chloride