title: [Detection of the activation of alveolar lymphocytes in alveolar proteinosis].
abstract: In 7 patients with pulmonary alveolar proteinosis, differential cytology and lymphocyte subsets in BAL fluid were investigated. The study showed that pulmonary alveolar proteinosis is another disorder characterized by a lymphocytic alveolitis and activation of T-lymphocytes (expression of HLA-DR antigens and IL-2 receptors). Our data indicate that immunological mechanisms involving T-cell activation may contribute to be pathogenesis of pulmonary alveolar proteinosis.
authors.affiliation: Ruhrlandklinik Essen-Heidhausen, Medizinischen Universitätsklinik Freiburg.
authors.forename: H
authors.initials: H
authors.lastname: Teschler
authors.forename: R
authors.initials: R
authors.lastname: Ziesche
authors.forename: H
authors.initials: H
authors.lastname: Matthys
authors.forename: D
authors.initials: D
authors.lastname: Greschuchna
authors.forename: N
authors.initials: N
authors.lastname: Konietzko
authors.forename: J
authors.initials: J
authors.lastname: Guzman
authors.forename: U
authors.initials: U
authors.lastname: Costabel
mesh_terms: D000328:Adult; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology; D006801:Humans; D007958:Leukocyte Count; D008213:Lymphocyte Activation / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D011649:Pulmonary Alveolar Proteinosis / Q000276:immunology*; D011658:Pulmonary Fibrosis / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*
vernacular_title: Nachweis der Aktivierung alveolärer Lymphozyten bei Alveolarproteinose.