title: [Fading of the provocation effect following inhaled provocation with carbachol].
abstract: The results of the present study aimed at establishing the subsidence of the effect of inhalative provocation with carbachol show that no ceiling activity is reached. Rather, following a maximum effect that is achieved after approximately 2 minutes, spontaneous subsidence of the provocation-related changes occurs. The average duration of this subsidence to below the level of change that is considered significant for the respective measured parameter was between 20 and 25 minutes.
authors.affiliation: III. Med. Klinik-Schwerpunkt Pneumologie, Univ.-Kliniken Mainz.
authors.forename: J
authors.initials: J
authors.lastname: Schlegel
authors.forename: V
authors.initials: V
authors.lastname: Schulz
mesh_terms: D000328:Adult; D000403:Airway Resistance / Q000187:drug effects*; D001249:Asthma / Q000175:diagnosis*; D001985:Bronchial Provocation Tests / Q000379:methods*; D002217:Carbachol; D005260:Female; D005541:Forced Expiratory Volume / Q000187:drug effects*; D006801:Humans; D008297:Male
chemical_list: D002217:Carbachol
vernacular_title: Untersuchungen zum Abklingen der Provokationswirkung nach inhalativer Provokation mit Carbachol.