title: Distinctive cataract in the Stickler syndrome.
abstract: We determined the clinical characteristics of cataract in 133 patients with the Stickler syndrome. Cataracts of various types or aphakia were found in 115 of 231 eyes (49.8%) studied. The most frequent and distinctive lesions, described as wedge and fleck cataracts, accounted for 40 of the 93 cataracts (43.0%) observed. These distinctive opacities may serve as a clinical marker for the Stickler syndrome and facilitate early diagnosis.
authors.affiliation: Retina Associates, Eye Research Institute, Boston, MA 02114.
authors.forename: C M
authors.initials: CM
authors.lastname: Seery
authors.forename: R C
authors.initials: RC
authors.lastname: Pruett
authors.forename: R M
authors.initials: RM
authors.lastname: Liberfarb
authors.forename: B Z
authors.initials: BZ
authors.lastname: Cohen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001035:Aphakia / Q000453:epidemiology; D002386:Cataract / Q000453:epidemiology / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D005128:Eye Diseases / Q000235:genetics / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D013577:Syndrome