[Superoxide dismutase activity as an index of the toxic action of pesticides].
A biochemical method for evaluation of the pesticide effect on the living organisms has been proposed. The key enzyme of antioxidant protection, superoxide dismutase (SOD) serves as an index of toxic influence. In the experiments with mollusks Physa, the inhibition of enzyme under the action of pesticides has been revealed. A reverse dependence between the activity of SOD and the number of perished mollusks has been revealed on the background of increased concentration of toxicant. The proposed method is delicate, simple, sufficiently informative, with the help of it the determination of permissible concentration of adverse substances considerably accelerates.
Karnaukhova
T B
TB
Korobova
L N
LN
Reĭkh
E M
EM
D000818:Animals; D004305:Dose-Response Relationship, Drug; D007306:Insecticides / Q000633:toxicity; D008974:Mollusca / Q000187:drug effects / Q000201:enzymology; D009570:Nitriles; D010575:Pesticides / Q000633:toxicity*; D011722:Pyrethrins / Q000633:toxicity; D013482:Superoxide Dismutase / Q000037:antagonists & inhibitors*
D007306:Insecticides; D009570:Nitriles; D010575:Pesticides; D011722:Pyrethrins; C017160:cypermethrin; D013482:Superoxide Dismutase; C017690:fenvalerate
Aktivnost' superoksiddismutazy kak pokazatel' toksicheskogo deĭstviia pestitsidov.