[Surfactant phospholipids in bronchoalveolar lavage fluid in smokers with healthy lungs and non-smokers].
The surfactant phospholipids were determined in the BA1 fluid of 9 smokers and 9 non-smokers with no disease of the lungs. The total phospholipid content was reduced significantly in smokers to 10 +/- 6 nmol/ml as compared with 24 +/- 10 nmol/ml in the non-smokers (p less than 0.02). The composition of major phospholipid fractions (phosphatidyl-choline and phosphatidyl-ethanolamine) did not differ between the two groups. Possible reasons for this reduction of surfactant in smokers are discussed.
Würtemberger
G
G
Abteilung Pneumologie, Universitätsklinik Freiburg.
Herceg
R
R
Matthys
H
H
Ferber
E
E
Costabel
U
U
D001992:Bronchoalveolar Lavage Fluid / Q000032:analysis*; D006801:Humans; D010713:Phosphatidylcholines / Q000032:analysis; D010714:Phosphatidylethanolamines / Q000032:analysis; D010743:Phospholipids / Q000032:analysis*; D011663:Pulmonary Surfactants / Q000032:analysis*; D012907:Smoking / Q000009:adverse effects*
D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D010743:Phospholipids; D011663:Pulmonary Surfactants
Surfactant-Phospholipide der BAL-Flüssigkeit bei lungengesunden Rauchern und Nichtrauchern.