[Ultrastructure of hemangio-endothelioma of the bone].
Specimens of hemangio-endothelioma of bone from 3 patients were prepared and scrupulously analyzed with light and electron microscopes. The main findings are summarized as follows: (1) The tumour cells are of endothelial nature to form vascular spaces lined with atypical endothelial cells which bulge into the lumen. (2) Most tumour cells have a good number of organellae, especially plasmic vesicles and filaments in cytoplasm. (3) Many tumour cells are closely opposite with bridging granules in between. These features are the differentiating points of hemangio-endothelioma from other bone tumours. The plasmic vesicles are of particular interest in their function which has not yet been made clear. They may either be a structure for transporting large molecular substance including endocytosis, intracytosis and exocytosis, or a temporary storage of membrane or of plasma.
Bi
W C
WC
Beijing Institute of Traumautology and Orthopedics.
D001859:Bone Neoplasms / Q000648:ultrastructure*; D006801:Humans; D012512:Sarcoma, Ewing / Q000648:ultrastructure*