Merkel cell tumor of the back detected during pregnancy.
Merkel cell tumor is an unusual, aggressive malignancy of skin that has been considered to be derived from cutaneous Merkel cells. We are reporting a case of Merkel cell tumor overlying the left scapula with metastases to the thoracic spine and pleura. The tumor was found incidentally in a 23-year-old pregnant black woman. The tumor recurred locally 5 months after initial wide excision. Subsequently, a second wide excision of the recurrent tumor with ipsilateral axillary dissection was performed. The course of the disease was complicated by local recurrence and formation of distant metastases to pleura and spine. At the end-stage of the disease, the patient was found to have a cardiac murmur, and echocardiography revealed a mass in the anterior wall of the right ventricle that was suspicious for a metastatic lesion. The patient expired from extensive distant metastases 23 months after diagnosis.
Chao
T C
TC
Department of Surgery, University of Illinois College of Medicine, Chicago.
Park
J M
JM
Rhee
H
H
Greager
J A
JA
D000328:Adult; D001415:Back; D015266:Carcinoma, Merkel Cell / Q000473:pathology* / Q000601:surgery; D005260:Female; D006338:Heart Neoplasms / Q000556:secondary; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D010997:Pleural Neoplasms / Q000556:secondary; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology* / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery; D013125:Spinal Neoplasms / Q000556:secondary