[A quantitative study on invasive process of mouse uterine cervix carcinoma (U14) cells implanted subcapsularly in testis].
Computer-image processing system was used for the quantitative study on tumor invasion in vivo in this experiment. Fragments of U14 tumor were subcapsularly transplanted in testis of the inbred 615-line mouse. One of serial sections (5-8 microns) through the thickest site of the inoculated tumor was selected and stained by PAP for quantitative study of the tumor invasion on day 1, 3, 5, 7, 9, 11 after transplantation. Both the volume of the lesion region and that of the total region were calculated. The invasion of U14 tumor cells in testis was shown to be progressive. The computer-image processing system is a good method for quantitative study of tumor invasion.
Huang
J W
JW
Institute of Bosic Medical Sciences, Chinese Academy of Medical Sciences, Beijing.
D000818:Animals; D005260:Female; D007091:Image Processing, Computer-Assisted; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009361:Neoplasm Invasiveness; D009368:Neoplasm Transplantation; D013737:Testis / Q000473:pathology*; D002583:Uterine Cervical Neoplasms / Q000473:pathology*