[Simplified intraarterial infusion and angiographic method for rabbit VX-2 hind limb tumor via the saphenous artery].
We developed a new simplified intraarterial infusion and angiographic method for rabbit VX-2 hind limb tumors. A 24 gauge cannula was placed in the saphenous artery of the tumor-bearing leg (not supplying the tumor) and used for intraarterial drug infusion or angiography. This method has several advantages as follows: 1) easy and time-saving in manipulation (about 15 minutes per a rabbit); 2) selective drug infusion into the tumor-supplying artery without fluoroscopy; 3) sequential follow-up angiographies available for weeks.
Homma
Y
Y
Department of Radiology, Yamaguchi University School of Medicine.
Suda
H
H
Ebe
K
K
Hatanaka
M
M
Nakanishi
T
T
D000818:Animals; D004317:Doxorubicin / Q000008:administration & dosage* / Q000493:pharmacokinetics; D006614:Hindlimb / Q000098:blood supply; D007261:Infusions, Intra-Arterial / Q000379:methods; D008297:Male; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000098:blood supply* / Q000188:drug therapy; D011150:Popliteal Artery / Q000000981:diagnostic imaging*; D011817:Rabbits; D011859:Radiography; D014018:Tissue Distribution
D004317:Doxorubicin