Alpha-1-antitrypsin phenotypes in leukaemia and lymphoma.
Serum samples from 564 Caucasian patients suffering from either leukaemia or lymphoma were typed for the protease inhibitor (Pi) alpha-1-antitrypsin (AAT). No evidence was found for the predisposition of any Pi phenotype to leukaemia or lymphoma. However, the frequency of PiM3 was significantly lowered among patients with acute myeloid leukaemia.
Janardhana
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Department of Applied Biology, Royal Melbourne Institute of Technology, Australia.
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D006801:Humans; D007938:Leukemia / Q000235:genetics*; D015470:Leukemia, Myeloid, Acute / Q000235:genetics; D008223:Lymphoma / Q000235:genetics*; D010641:Phenotype; D000515:alpha 1-Antitrypsin / Q000235:genetics*
D000515:alpha 1-Antitrypsin