Transgenic mice expressing the bacterial O6 alkylguanine-DNA alkyltransferase gene: an animal model to study the role of DNA repair in the carcinogenesis of N-nitroso compounds.
Dumenco
L L
LL
Ireland Cancer Center, OH.
Donovan
C
C
Warman
B
B
Clapp
D W
DW
Lim
I K
IK
Yun
J
J
Wagner
T
T
Hanson
R W
RW
Gerson
S L
SL
D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics*; D004260:DNA Repair; D004790:Enzyme Induction; D005838:Genotype; D008780:Methyltransferases / Q000096:biosynthesis / Q000235:genetics*; D051379:Mice; D008822:Mice, Transgenic / Q000235:genetics*; D009603:Nitroso Compounds / Q000494:pharmacology*; D019853:O(6)-Methylguanine-DNA Methyltransferase; D009928:Organ Specificity; D010729:Phosphoenolpyruvate Carboxykinase (GTP) / Q000096:biosynthesis / Q000235:genetics; D011401:Promoter Regions, Genetic; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis / Q000235:genetics
D001426:Bacterial Proteins; D009603:Nitroso Compounds; D011993:Recombinant Fusion Proteins; D008780:Methyltransferases; D019853:O(6)-Methylguanine-DNA Methyltransferase; D010729:Phosphoenolpyruvate Carboxykinase (GTP)