title: [IgG subclass distribution in the serum of patients with homozygous alpha1-antitrypsin deficiency].
abstract: In 12 patients with homozygotic ZZ-phenotype alpha 1 antitrypsin deficiency, the serum levels of the IgG subclasses IgG1-4 were studied. In four of these patients, isolated or combined disorders or defects in the distribution of the IgG subclasses were detected; in cases with low IgG2 and absent IgG3, the clinical course of the disease was complicated by bronchiectasis.
authors.affiliation: Medizinische Klinik Bergmannsheil, Ruhr-Universität, Bochum.
authors.forename: J
authors.initials: J
authors.lastname: Barth
authors.forename: I
authors.initials: I
authors.lastname: Winkler
authors.forename: E W
authors.initials: EW
authors.lastname: Schmidt
authors.forename: B E
authors.initials: BE
authors.lastname: Braun
authors.forename: H W
authors.initials: HW
authors.lastname: Möllmann
authors.forename: F
authors.initials: F
authors.lastname: Skvaril
mesh_terms: D000328:Adult; D000361:Agammaglobulinemia / Q000235:genetics*; D001987:Bronchiectasis / Q000235:genetics*; D005260:Female; D006720:Homozygote; D006801:Humans; D017099:IgG Deficiency; D007074:Immunoglobulin G / Q000145:classification*; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D012141:Respiratory Tract Infections / Q000235:genetics*; D019896:alpha 1-Antitrypsin Deficiency
chemical_list: D007074:Immunoglobulin G
vernacular_title: IgG-Subklassenverteilung im Serum von Patienten mit homozygotem alpha 1-Antitrypsinmangel.