title: Urethral dilation improves bladder compliance in children with myelomeningocele and high leak point pressures.
abstract: Among 350 children with myelomeningocele 18 with elevated leak point pressures were managed by urethral dilation and followed for 1 to 5 years. Longitudinal measurements of bladder compliances revealed durable improvement in the pressure-volume relationships after dilation. These data suggest that noncompliant bladders are acquired because of high outlet resistance, and early intervention may improve long-term bladder storage characteristics.
authors.affiliation: Department of Surgery, University of Michigan, Ann Arbor.
authors.forename: D A
authors.initials: DA
authors.lastname: Bloom
authors.forename: J M
authors.initials: JM
authors.lastname: Knechtel
authors.forename: E J
authors.initials: EJ
authors.lastname: McGuire
mesh_terms: D002648:Child; D002675:Child, Preschool; D004106:Dilatation; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008591:Meningomyelocele / Q000150:complications / Q000503:physiopathology*; D014521:Urethra; D001743:Urinary Bladder / Q000503:physiopathology*; D001750:Urinary Bladder, Neurogenic / Q000503:physiopathology / Q000628:therapy*; D014546:Urinary Catheterization; D014563:Urodynamics