[Trypsin and pancreatic elastase-inhibitory capacity of serum and bronchoalveolar lavage fluid of smokers, ex-smokers and nonsmokers].
Smoking habits have no differentiating effect on the functional activity of protease inhibitor (alpha 1PI) in the serum and bronchoalveolar lavage fluid (BALF). In the BALF, the trypsin-inhibitory capacity TIC/alpha 1PI ratio is significantly greater in patients with emphysema than in non-emphysematous subjects. PIC/alpha 1PI ratios that are greater than 1 demonstrate the existence of additional antiproteases in the lower respiratory tract.
Ebert
W
W
Thoraxklinik Heidelberg-Rohrbach.
Trefz
G
G
Heck
B
B
Schulz
V
V
D001992:Bronchoalveolar Lavage Fluid / Q000032:analysis*; D006801:Humans; D010196:Pancreatic Elastase / Q000037:antagonists & inhibitors*; D011656:Pulmonary Emphysema / Q000201:enzymology*; D012907:Smoking / Q000097:blood*; D014361:Trypsin Inhibitors / Q000097:blood*; D000515:alpha 1-Antitrypsin / Q000378:metabolism*
D014361:Trypsin Inhibitors; D000515:alpha 1-Antitrypsin; D010196:Pancreatic Elastase
Trypsin- und Pankreaselastase-inhibitorische Kapazität von Serum und bronchoalveolärer Lavageflüssigkeit bei Rauchern, Exrauchern und Nichtrauchern.