Recent time trends in uterine cancer.
Recent trends in corpus uterine cancer incidence rates were explored using 1979-86 data from the Surveillance and End Results Program (SEER); recent trends in hospitalizations for corpus uterine cancer were explored using 1979-86 data from National Hospital Discharge Surveys (NHDS); and recent trends in exogenous hormone use were delineated using data from the 1980, 1981, and 1985 National Ambulatory Medical Care Surveys (NAMCS). Uterine cancer incidence rates using SEER data have continued to decline since 1979. An acceleration in the decline since 1983-84 is suggested in all women and in women with intact uteri ages 45-64. Hospitalizations for uterine cancer have also declined since 1979, with a marked acceleration in the decline since 1983-84 for all women and for women ages 40-79 has increased 22 percent and use of unopposed exogenous estrogens in women of similar age has increased 7 percent, while use of exogenous progesterones have shown much more substantial increases of approximately 700 percent. Possible relationships between trends in exogenous hormone use and incidence rates of corpus uterine cancer are discussed.
Persky
V
V
Epidemiology Program, School of Public Health, University of Illinois, Chicago 60680.
Davis
F
F
Barrett
R
R
Ruby
E
E
Sailer
C
C
Levy
P
P
D000328:Adult; D000368:Aged; D016001:Confidence Intervals; D004359:Drug Therapy, Combination; D004967:Estrogens / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data / Q000639:trends; D006801:Humans; D008875:Middle Aged; D011374:Progesterone / Q000008:administration & dosage / Q000627:therapeutic use; D011372:Progestins / Q000627:therapeutic use; D011647:Puerto Rico / Q000453:epidemiology; D012044:Regression Analysis; D014481:United States / Q000453:epidemiology; D014594:Uterine Neoplasms / Q000453:epidemiology*
D004967:Estrogens; D011372:Progestins; D011374:Progesterone