title: Long-term impairments of brain and auditory functions of children recovered from purulent meningitis.
abstract: Sixty children who had recovered from purulent meningitis one to six years earlier were investigated for long-term impairment of brain and auditory function, using brainstem auditory evoked potentials(BAEP) and developmental screening tests. Neurological and/or audiological BAEP abnormalities were found in 23 per cent of the children: 15 per cent had mild brainstem impairment and 12 per cent had hearing dysfunction. Developmental screening tests were administered to 46 children, of whom 61 per cent had normal, 22 per cent questionable and 17 per cent abnormal results. The results of the BAEP significantly correlated with those of the developmental screening tests, suggesting that the neuropsychological development of children with BAEP abnormalities was significantly delayed compared with that of children without BAEP abnormalities. The characteristic finding in a neurologically abnormal BAEP was slightly depressed amplitude of wave V, and the authors suggest that this is the most sensitive BAEP measure for the assessment of brainstem function in children recovered from meningitis.
authors.affiliation: Department of Child Health, Children's Hospital, Shanghai Medical University, P.R.C.
authors.forename: Z D
authors.initials: ZD
authors.lastname: Jiang
authors.forename: X Y
authors.initials: XY
authors.lastname: Liu
authors.forename: Y Y
authors.initials: YY
authors.lastname: Wu
authors.forename: M S
authors.initials: MS
authors.lastname: Zheng
authors.forename: H C
authors.initials: HC
authors.lastname: Liu
mesh_terms: D000161:Acoustic Stimulation; D001927:Brain Diseases / Q000209:etiology* / Q000503:physiopathology; D001933:Brain Stem / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D005072:Evoked Potentials, Auditory; D005260:Female; D006311:Hearing Disorders / Q000209:etiology*; D006801:Humans; D008297:Male; D008581:Meningitis / Q000150:complications*