[Erythrocyte membrane permeability to monovalent ions of sodium and potassium in adolescents with essential arterial hypertension and renal hypertension].
In healthy adolescents, patients with essential hypertension (EH) or symptomatic (renal) hypertension (SRH), erythrocyte electrolyte composition and membrane permeability were studied for Na+ and K+ (as an example Na+ and K+ current rates being studied by the Garay and Meyer method, 1979). Study into the erythrocyte Na+ and K+ concentrations in adolescents demonstrated that those having EH exhibited higher Na+ concentrations than in healthy ones. The adolescents with EH showed abnormal erythrocyte membrane permeability that appeared as changed Na+ and K+ current rates. Such changes were not detected in the erythrocytes of adolescents with SRH. The results of the study into erythrocyte membrane permeability in healthy adolescents and patients with EH or SRH confirm the fact that this index may be used as an additional test for differential diagnosis of EH and SRH.
Kavtaradze
V G
VG
Nadiradze
N I
NI
Lomouri
M A
MA
Chachava
T M
TM
D000293:Adolescent; D002463:Cell Membrane Permeability / Q000502:physiology*; D004910:Erythrocyte Membrane / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000097:blood*; D006977:Hypertension, Renal / Q000097:blood*; D066298:In Vitro Techniques; D011188:Potassium / Q000097:blood* / Q000493:pharmacokinetics; D012964:Sodium / Q000097:blood* / Q000493:pharmacokinetics
D012964:Sodium; D011188:Potassium
Pronitsaemost' membran éritrotsitov dlia odnovalentnykh ionov natriia i kaliia u podrostkov s essentsial'noĭ arterial'noĭ gipertenzieĭ i gipertenzieĭ pochechnogo geneza.