title: Subcutaneous fat necrosis associated with pancreatitis: histochemical and electron microscopic findings.
abstract: Subcutaneous fat necrosis associated with pancreatitis has been postulated to be due to the effects of circulating pancreatic lipase. We report positive intracellular staining of adipocytes with a monoclonal antibody to pancreatic lipase in a lesion of subcutaneous pancreatic fat necrosis, and confirm the role of pancreatic lipase in the pathogenesis of this syndrome.
authors.affiliation: Department of Dermatology, Mt. Sinai Medical Center, Miami Beach, Florida.
authors.forename: S S
authors.initials: SS
authors.lastname: Dhawan
authors.forename: F
authors.initials: F
authors.lastname: Jimenez-Acosta
authors.forename: R J
authors.initials: RJ
authors.lastname: Poppiti
authors.forename: J S
authors.initials: JS
authors.lastname: Barkin
mesh_terms: D000273:Adipose Tissue / Q000201:enzymology / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008049:Lipase / Q000032:analysis; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D010195:Pancreatitis / Q000150:complications* / Q000201:enzymology; D015434:Panniculitis / Q000150:complications* / Q000201:enzymology / Q000473:pathology
chemical_list: D008049:Lipase