title: [Chronic ITP with a remarkable response to vitamin C administration after splenectomy].
abstract: This report deals with a case of 23-year-old woman with chronic idiopathic thrombocytopenic purpura (ITP) showing a favorable response to vitamin C (VC) administration. She was treated with glucocorticoids and immunosuppressants, whereas inadequately controlled with its tolerable dosage. Next, she underwent splenectomy. However, there were only transient effects on platelet counts, so the therapy with ascorbate was carried out according to the report by Brox et al. The platelet counts increased to 20 x 10(4)/microliters after 4 months. Side effects of VC therapy did not occur.
authors.affiliation: First Department of Internal Medicine, Kansai Medical University.
authors.forename: S
authors.initials: S
authors.lastname: Nomura
authors.forename: M
authors.initials: M
authors.lastname: Yanabu
authors.forename: T
authors.initials: T
authors.lastname: Soga
authors.forename: T
authors.initials: T
authors.lastname: Fukuroi
authors.forename: H
authors.initials: H
authors.lastname: Kido
authors.forename: H
authors.initials: H
authors.lastname: Nagata
authors.forename: T
authors.initials: T
authors.lastname: Kokawa
authors.forename: K
authors.initials: K
authors.lastname: Yasunaga
mesh_terms: D000328:Adult; D001205:Ascorbic Acid / Q000627:therapeutic use*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D011182:Postoperative Care; D011696:Purpura, Thrombocytopenic / Q000188:drug therapy* / Q000601:surgery; D013156:Splenectomy
chemical_list: D001205:Ascorbic Acid