title: [Studies of the dependence of alkoxycyanodiphenyl toxicity on structure with the aim of health-related group standardization].
abstract: The article presents results of toxicity and hazard effects studies of alcoxicyandiphenyl CnH2n+ 1OC12H8CN with n = 1-8, octilcyandiphenyl and octildiphenyl. Toxicity parameters were established in animal tests and on isolated mitochondria, and inhibiting concentrations were calculated. Correlation was established between the alcoxicyandiphenyl detainment in high-performance liquid chromatography and the inhibition rate constant. The allowable and hazard levels are also specified.
authors.forename: B A
authors.initials: BA
authors.lastname: Kurliandskiĭ
authors.forename: E L
authors.initials: EL
authors.lastname: Balabanova
authors.forename: A M
authors.initials: AM
authors.lastname: Kliachkina
authors.forename: E V
authors.initials: EV
authors.lastname: Braude
authors.forename: I V
authors.initials: IV
authors.lastname: Pervukhina
mesh_terms: D000818:Animals; D001713:Biphenyl Compounds / Q000032:analysis / Q000592:standards / Q000633:toxicity*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D002851:Chromatography, High Pressure Liquid; D066298:In Vitro Techniques; D007928:Lethal Dose 50; D008452:Maximum Allowable Concentration; D051379:Mice; D008930:Mitochondria, Liver / Q000187:drug effects; D009570:Nitriles / Q000032:analysis / Q000592:standards / Q000633:toxicity*; D011817:Rabbits; D051381:Rats
chemical_list: D001713:Biphenyl Compounds; D009570:Nitriles
vernacular_title: Izuchenie zavisimosti toksichnosti alkoksitsiandifenilov ot ikh struktury s tsel'iu gruppovogo gigienicheskogo normirovaniia.