title: Clinical and angiographic recurrence following PTCA for nonacute total occlusions: comparison of one- versus five-minute inflations.
abstract: To assess potential efficacy of longer inflations to reduce restenosis, 49 patients with nonacute total occlusions were randomized into two groups after successful guide wire passage across the occlusive stenosis. Twenty-one group I patients had all inflations less than 1 minute, while 28 group II patients received at least one inflation of 5 minutes' duration. There was no significant difference between group I and group II patients in mean age (56 +/- 3 versus 57 +/- 2 years), percent male sex (76% versus 68%), or frequency of left anterior descending (LAD) percutaneous transluminal coronary angioplasty (PTCA) (33% versus 32%), p = NS for all. All lesions post PTCA were less than or equal to 50% stenosed and no patient had coronary artery bypass surgery (CABG). Mean post PTCA stenosis was 29 +/- 2% for group I versus 33 +/- 2% for group II, p = NS. Clinical follow-up was available for all patients 8 +/- 0.6 months after PTCA. Recurrent symptoms were present in 8 of 21 (38%) group I patients compared with 12 of 28 (43%) patients in group II, p = NS. Angiographic follow-up was available in 32 patients (65%), with confirmation of restenosis in seven (33%) group I patients and in 11 (39%) group II patients, p = NS. In conclusion, this prospective study suggests that recurrence rates following successful PTCA of nonacute total occlusions is not modified by 5-minute versus 1-minute inflations.
authors.affiliation: Department of Medicine, Medical College of Virginia, Richmond 23298.
authors.forename: G
authors.initials: G
authors.lastname: DiSciascio
authors.forename: G W
authors.initials: GW
authors.lastname: Vetrovec
authors.forename: S A
authors.initials: SA
authors.lastname: Lewis
authors.forename: A
authors.initials: A
authors.lastname: Nath
authors.forename: S K
authors.initials: SK
authors.lastname: Cole
authors.forename: V L
authors.initials: VL
authors.lastname: Edwards
mesh_terms: D000792:Angiography; D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D017023:Coronary Angiography; D003327:Coronary Disease / Q000503:physiopathology / Q000628:therapy; D005500:Follow-Up Studies; D006801:Humans; D011183:Postoperative Complications; D012008:Recurrence; D013997:Time Factors