title: Effect of isosorbide dinitrate on enzymatically estimated infarction size and on clinical condition of the patients of acute myocardial infarction.
abstract: With the aim of reducing myocardial infarction size, isosorbide dinitrate (ISDN) was tried in 27 patients of acute myocardial infarction (AMI). There was 11% reduction of infarction size, in the ISDN treated group, in comparison to that of non treated group, though the result was not statistically significant. But, many of the in-hospital complications were significantly less in the treated group. After a critical analysis of the result it was concluded that a statistically insignificant result, as regard reduction of infarction size in AMI, cannot always exclude the utility of a drug therapy in AMI.
authors.affiliation: N.R.S. Medical College, Calcutta.
authors.forename: D
authors.initials: D
authors.lastname: Mukherjee
authors.forename: S K
authors.initials: SK
authors.lastname: Lodh
authors.forename: M
authors.initials: M
authors.lastname: Sengupta
authors.forename: A K
authors.initials: AK
authors.lastname: Maity
authors.forename: A K
authors.initials: AK
authors.lastname: Mondal
authors.forename: J C
authors.initials: JC
authors.lastname: Ghose
mesh_terms: D003402:Creatine Kinase / Q000032:analysis; D005260:Female; D006801:Humans; D007527:Isoenzymes; D007548:Isosorbide Dinitrate / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000201:enzymology
chemical_list: D007527:Isoenzymes; D003402:Creatine Kinase; D007548:Isosorbide Dinitrate