[Prognosis factors in adenocarcinoma of the kidney. III. Nuclear area].
Nuclear morphometry was performed with the MOP-Videoplan morphometry device in 95 cases of renal adenocarcinoma submitted to radical nephrectomy and hilar lymphadenectomy with a 5-year follow-up. For each case, 100 nuclei were randomly selected and delineated (magnification: 1,000x). A statistically significant correlation (p less than 0.05) was observed for the nuclear area and the overall as well as stage-related survivorship. Using a nuclear size of 35 microns 2, the study population can be divided into two groups: those with a good and those with a poor prognosis regardless of stage. A statistically significant difference was observed for the overall as well as the stage-related survivorship for the group with a nuclear area less than 35 microns 2 (good prognosis) in comparison with the group with a nuclear area greater than 35 microns 2.
Gutiérrez
J L
JL
Departamento de Anatomía Patológica, Hospital Nacional Marqués de Valdecila, Santander, España.
Val-Bernal
J F
JF
Portillo
J A
JA
Garijo
F
F
Buelta
L
L
D000230:Adenocarcinoma / Q000401:mortality / Q000648:ultrastructure*; D002467:Cell Nucleus / Q000648:ultrastructure*; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000401:mortality / Q000648:ultrastructure*; D009367:Neoplasm Staging; D011379:Prognosis; D015996:Survival Rate
Factores pronósticos en el adenocarcinoma renal. III. Area nuclear.