title: The cis-configuration effects of rare chromosomal fragile sites.
abstract: Rare chromosomal fragile sites may adversely affect specific alleles of closely linked genes when in cis-configuration. This is illustrated by data published in Sutherland & Hecht (1985) on chromosome 16 at band q22.1.
authors.affiliation: Genetics Division, Institute of Child Health, Athens, Greece.
authors.forename: G B
authors.initials: GB
authors.lastname: Côté
mesh_terms: D000483:Alleles; D043283:Chromosome Fragile Sites; D002873:Chromosome Fragility; D002885:Chromosomes, Human, Pair 16; D003434:Crossing Over, Genetic; D008040:Genetic Linkage; D006801:Humans; D010641:Phenotype