title: Childhood aplastic anaemia in Kenya.
abstract: Forty two children with aplastic anaemia were seen at Kenyatta National Hospital, Nairobi, over a period of 8 years (1980-1988). These have been analysed with respect to sex, age and area of geographical origin. The overall male:female ratio is 1:1 with a preponderance of Kikuyu patients. Repeated transfusions was the commonest presenting feature and rapid onset was associated with poor prognosis. Exposure to herbicides/pesticides and other agrochemicals is implicated in the aetiopathogenesis of childhood aplastic anaemia in Kenya.
authors.affiliation: Department of Pathology, College of Health Sciences, University of Nairobi, Kenya.
authors.forename: M S
authors.initials: MS
authors.lastname: Riyat
authors.forename: E G
authors.initials: EG
authors.lastname: Kasili
authors.forename: W O
authors.initials: WO
authors.lastname: Mwanda
mesh_terms: D000293:Adolescent; D000741:Anemia, Aplastic / Q000139:chemically induced / Q000453:epidemiology* / Q000473:pathology; D015984:Causality; D002648:Child; D002675:Child, Preschool; D005260:Female; D006540:Herbicides / Q000009:adverse effects; D006801:Humans; D007223:Infant; D007630:Kenya; D008297:Male; D010575:Pesticides / Q000009:adverse effects; D011446:Prospective Studies; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D006540:Herbicides; D010575:Pesticides