title: Evaluation of the effects of antigen specific immunotherapy on chronic sinusitis in children with allergy.
abstract: The purpose of this study is to evaluate the clinical significance of allergy in children with chronic sinusitis. After allergic examinations, 52 sinusitis children were divided into allergic and non-allergic groups: 37 allergic children were treated with either the combination of antigen specific immunotherapy and medication with lysozyme chloride preparation (AI group, n = 20) or medication alone (AM group, n = 17); 15 non-allergic patients were also treated with lysozyme chloride preparation (NAM group). The treatment results including the radiographic improvements were significantly better in the AI group than in the AM or NAM group. The clinical effects of lysozyme chloride preparation tended to be better in the NAM group than in the AM group.
authors.affiliation: Department of Otolaryngology, Sapporo Medical College, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Asakura
authors.forename: T
authors.initials: T
authors.lastname: Kojima
authors.forename: H
authors.initials: H
authors.lastname: Shirasaki
authors.forename: A
authors.initials: A
authors.lastname: Kataura
mesh_terms: D000485:Allergens / Q000276:immunology; D000941:Antigens / Q000008:administration & dosage / Q000276:immunology; D002648:Child; D002908:Chronic Disease; D006801:Humans; D006967:Hypersensitivity / Q000150:complications / Q000276:immunology / Q000628:therapy*; D007167:Immunotherapy / Q000379:methods*; D009113:Muramidase / Q000627:therapeutic use; D009299:Nasal Provocation Tests; D011852:Radioallergosorbent Test; D012852:Sinusitis / Q000150:complications / Q000276:immunology / Q000628:therapy*; D012882:Skin Tests
chemical_list: D000485:Allergens; D000941:Antigens; D009113:Muramidase