title: Rheumatic disorders in Zimbabwe: a prospective analysis of patients attending a rheumatic diseases clinic.
abstract: The pattern of rheumatic disease in Africa differs from that in Europe and the United States and these differences may provide clues to its cause or pathogenesis. In a six month prospective analysis of 141 patients (83 female) attending a rheumatic diseases clinic rheumatoid arthritis was the commonest disorder, occurring in 49 patients. Twenty seven of the 49 (55%) were seropositive, 25 (51%) had erosive disease with rheumatoid nodules (13/49, 27%), and extra-articular complications (6/49, 12%), indicating a pattern of disease unlike the early reports from Africa. Systemic lupus erythematosus found in 18/141 (13%), gout in 12 (9%), ankylosing spondylitis in six (4%), and Reiter's syndrome in five (4%), in contrast with their rarity in previous reports from Africa, were not uncommon, whereas tropical polyarthritis was seldom diagnosed. The pattern of rheumatic disease in Harare, a large city, is changing to approximate more closely the pattern seen in developed countries.
authors.affiliation: Department of Clinical Pharmacology, University of Zimbabwe, Avondale, Harare.
authors.forename: M
authors.initials: M
authors.lastname: Stein
authors.forename: P
authors.initials: P
authors.lastname: Davis
mesh_terms: D000328:Adult; D016918:Arthritis, Reactive / Q000453:epidemiology; D001172:Arthritis, Rheumatoid / Q000453:epidemiology; D005260:Female; D006073:Gout / Q000453:epidemiology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000453:epidemiology; D008297:Male; D010044:Outpatient Clinics, Hospital; D011446:Prospective Studies; D012216:Rheumatic Diseases / Q000453:epidemiology*; D013167:Spondylitis, Ankylosing / Q000453:epidemiology; D015030:Zimbabwe / Q000453:epidemiology