The use of N-ethyl-N-nitrosourea to produce mouse models for human phenylketonuria and hyperphenylalaninemia.
McDonald
J D
JD
McArdle Laboratory, University of Wisconsin Medical School, Madison 53706.
Bode
V C
VC
Dove
W F
WF
Shedlovsky
A
A
D000592:Amino Acid Metabolism, Inborn Errors / Q000139:chemically induced / Q000235:genetics*; D000818:Animals; D003433:Crosses, Genetic; D004195:Disease Models, Animal; D005038:Ethylnitrosourea / Q000633:toxicity*; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D008817:Mice, Mutant Strains; D009154:Mutation; D010641:Phenotype; D010649:Phenylalanine / Q000097:blood*; D010661:Phenylketonurias / Q000139:chemically induced / Q000235:genetics*
D010649:Phenylalanine; D005038:Ethylnitrosourea