title: Influence of certain drugs on the densitometry results of optic lens sections in posterior subcapsular cataracts.
abstract: A clinical follow-up of 157 patients with initial changes in lens transparency demonstrated that the proteolytic drug Lekosim contributes to the restoration of the optic properties, primarily in those cases where opacities are located subcapsularly and parallel to the lens fibers in the surface cortical regions. As regards the combined use of Lekosim and Sencatalin for the treatment of diabetic patients with cataracts, it was found that the former enhanced the effect of the latter. A more pronounced reduction in the optic density of the cortical regions of the lens was observed in the combination treatment with the two drugs as compared with the use of Sencatalin alone.
authors.affiliation: All-Union Research Institute for Eye Diseases, USSR Ministry of Health, Moscow.
authors.forename: G S
authors.initials: GS
authors.lastname: Polunin
mesh_terms: D002386:Cataract / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D003720:Densitometry; D048909:Diabetes Complications; D004333:Drug Administration Routes; D004338:Drug Combinations; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D007908:Lens, Crystalline / Q000473:pathology*; D010781:Photography
chemical_list: D004338:Drug Combinations