Amphotericin B-related thrombocytopenia. A report of two cases.
Thrombocytopenia is a rare side effect of amphotericin B. Two patients with acute leukaemia in remission who developed severe thrombocytopenia during amphotericin B therapy are reported. Thrombocytopenia recovered after the withdrawal of the drug in one patient and after reducing the dose in the other patient.
Charak
B S
BS
Department of Medical Oncology, Tata Memorial Hospital, Parel, Bombay.
Iyer
R S
RS
Rajoor
B G
BG
Saikia
T K
TK
Gopal
R
R
Advani
S H
SH
D000328:Adult; D000666:Amphotericin B / Q000009:adverse effects* / Q000627:therapeutic use; D001228:Aspergillosis / Q000188:drug therapy*; D001996:Bronchopneumonia / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008172:Lung Diseases, Fungal / Q000188:drug therapy*; D008297:Male; D009894:Opportunistic Infections / Q000188:drug therapy*; D013921:Thrombocytopenia / Q000139:chemically induced*
D000666:Amphotericin B