[Comparison of salivary with serum levels of retard theophylline under steady-state conditions].
In 86 asthmatic children, the theophylline levels in the serum and saliva were compared. A pronounced (r = 0.95) and statistically highly significant (p less than 0.001) relationship was observed to exist between the theophylline concentrations in serum and saliva.
Virchow
C
C
Hochgebirgsklinik Davos, Davos-Wolfgang.
Schmitz-Schumann
M
M
Mansfeld
J
J
D000293:Adolescent; D001249:Asthma / Q000097:blood* / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D003692:Delayed-Action Preparations; D005260:Female; D006801:Humans; D008297:Male; D012463:Saliva / Q000378:metabolism*; D013806:Theophylline / Q000008:administration & dosage / Q000493:pharmacokinetics*
D003692:Delayed-Action Preparations; D013806:Theophylline
Vergleich von Saliva- mit Serumspiegeln bei Retardtheophyllin unter Steady-State-Bedingungen.