Malignant plasma cell tumors in human immunodeficiency virus-infected patients.
The development of malignant neoplasms in patients with the acquired immune deficiency syndrome (AIDS) or with a positive human immunodeficiency virus (HIV) antibody test is a well known phenomenon. According to the guidelines from the Centers for Disease Control (Atlanta, GA), the presence of intermediate-grade or high-grade B-cell non-Hodgkin's lymphoma in HIV antibody-positive patients is considered a diagnostic criterion for AIDS. The authors describe two cases of malignant plasma cell tumors in two young HIV-infected patients. In light of this and other reports of plasma cell tumors in patients at risk for AIDS or with a positive HIV antibody test, the finding of another manifestation of B-cell neoplasia in these patients may enlarge the spectrum of AIDS-related tumors.
Gold
J E
JE
Department of Medicine, Beth Israel Medical Center, Mount Sinai School of Medicine, New York, NY 10003.
Schwam
L
L
Castella
A
A
Pike
S B
SB
Opfell
R
R
Zalusky
R
R
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000473:pathology; D000328:Adult; D001853:Bone Marrow / Q000473:pathology; D006679:HIV Seropositivity / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D010413:Penis; D010954:Plasmacytoma / Q000150:complications* / Q000473:pathology; D012307:Risk Factors; D012878:Skin Neoplasms / Q000150:complications* / Q000473:pathology; D013909:Thorax