title: Refraction in diabetics during metabolic dysregulation, acute or chronic. With special reference to the diabetic myopia concept.
abstract: The influence of diabetic dysregulation on refraction was analysed by a short-term and a long-term approach. a) Out of 15 patients admitted due to high blood sugars and followed over weeks, 11 showed refractive fluctuation of 1-6.5 D, in either direction-often with excess hypermetropia, while 4 appeared refractively stable. In those with refractive change a transient increase of lens thickness was suggested from ultrasound measurements. b) Diabetes control was evaluated retrospectively in 74 adult diabetics, mainly based on repeated 24 h urine glucose determinations over a 6-year period. As a group, those with low myopia did not score worse than those who had stayed emmetropic. Among the myopes, diabetes duration was longer in the subgroup where diabetes preceded myopia onset. - All considered, we found no support for dysregulation per se as an underlying factor behind the 'diabetic myopia' previously reported from our clinic.
authors.affiliation: Department of Ophthalmology, Hillerød Central Hospital, Denmark.
authors.forename: H C
authors.initials: HC
authors.lastname: Fledelius
authors.forename: J
authors.initials: J
authors.lastname: Fuchs
authors.forename: A
authors.initials: A
authors.lastname: Reck
mesh_terms: D000208:Acute Disease; D000328:Adult; D000867:Anterior Chamber / Q000503:physiopathology; D001786:Blood Glucose / Q000378:metabolism; D002908:Chronic Disease; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000378:metabolism; D005260:Female; D006801:Humans; D007908:Lens, Crystalline / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000209:etiology* / Q000378:metabolism; D012029:Refraction, Ocular; D012030:Refractive Errors / Q000209:etiology* / Q000378:metabolism; D012189:Retrospective Studies
chemical_list: D001786:Blood Glucose