Allografted keratinocytes used to accelerate the treatment of burn wounds are replaced by recipient cells.
Cultured keratinocytes were used as allografts on burn wounds in two patients. In both patients successful covering of the wounds was obtained. DNA fingerprinting of the epidermis covering the wounds 21 days later showed that the cultured keratinocytes were replaced by the patients' cells.
van der Merwe
A E
AE
Department of Surgery, University of Stellenbosch Medical School, Tygerberg, Republic of South Africa.
Mattheyse
F J
FJ
Bedford
M
M
van Helden
P D
PD
Rossouw
D J
DJ
D000328:Adult; D001706:Biopsy; D002056:Burns / Q000473:pathology / Q000628:therapy*; D002478:Cells, Cultured; D004247:DNA / Q000032:analysis; D004817:Epidermis / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D015603:Keratinocytes / Q000637:transplantation* / Q000648:ultrastructure; D008297:Male; D008875:Middle Aged; D009710:Nucleotide Mapping; D014019:Tissue Donors; D014184:Transplantation, Homologous
D004247:DNA