Angiotrophic lymphoma. Presentation in uterine vessels with cytogenetic studies.
An unusual case of angiotrophic lymphoma diagnosed initially in the uterus is described. Immunohistochemical studies documented the intravascular tumor cells in the myometrium to be of B lymphocytic origin. The patient's bone marrow was hypercellular, and cytogenetic studies of the aspirate revealed a subpopulation of cells with multiple clonal chromosomal abnormalities. To our knowledge, this is the first case to document abnormal cytogenetic findings in this uncommon malignancy.
Davey
D D
DD
Department of Pathology, University of Kentucky Medical Center, Lexington 40536-0093.
Munn
R
R
Smith
L W
LW
Cibull
M L
ML
D001402:B-Lymphocytes; D001853:Bone Marrow / Q000473:pathology; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007150:Immunohistochemistry; D007621:Karyotyping; D008223:Lymphoma / Q000235:genetics / Q000473:pathology*; D008875:Middle Aged; D009360:Neoplastic Cells, Circulating / Q000473:pathology; D014594:Uterine Neoplasms / Q000235:genetics / Q000473:pathology*; D014599:Uterus / Q000098:blood supply