Direct quantitation of skin elasticity in systemic sclerosis.
A simple instrument, the "skin elastometer," was used to evaluate the elastic and plastic properties of volar forearm skin in 24 patients with systemic sclerosis and 24 healthy individuals matched for age, race and sex. Skin elastance in 17 patients with diffuse scleroderma was found to be significantly different from matched controls (p less than 0.001), and was associated with clinical skin scores independently determined by examination (r = 0.89, p less than 0.001). Seven patients with limited scleroderma (the CREST variant) had values for skin elastance which were intermediate between those of the patients with diffuse scleroderma and healthy persons. Plastic deformation of the stretched skin was similar in patients and controls. Quantitative measurement of skin elastance is a simple technique which may prove to be of value in the assessment of patients with systemic sclerosis.
Ballou
S P
SP
Department of Medicine, Case Western Reserve University, Cleveland Metropolitan General Hospital, OH 44109.
Mackiewicz
A
A
Lysikiewicz
A
A
Neuman
M R
MR
D000328:Adult; D000368:Aged; D004548:Elasticity; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000503:physiopathology*; D012879:Skin Physiological Phenomena; D012882:Skin Tests / Q000295:instrumentation / Q000379:methods