Effect of major surgery on absorption rate of NPH insulin injected s.c.
The absorption rate of NPH insulin injected s.c. was evaluated before operation and on the day of surgery by continuous measurements of residual radioactivity of 125I-labelled insulin in 10 patients undergoing major abdominal surgery. The results show that major surgery has no effect on rate of absorption of intermediate acting insulin.
Hjortrup
A
A
Department of Surgical Gastroenterology F, Bispebjerg Hospital, University of Copenhagen, Denmark.
Madsbad
S
S
Andersen
M
M
Sørensen
C
C
D000005:Abdomen / Q000601:surgery*; D000368:Aged; D005260:Female; D006801:Humans; D007279:Injections, Subcutaneous; D007336:Insulin, Isophane / Q000008:administration & dosage / Q000493:pharmacokinetics*; D007457:Iodine Radioisotopes / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D012039:Regional Blood Flow; D012867:Skin / Q000098:blood supply; D013997:Time Factors; D014980:Xenon Radioisotopes / Q000032:analysis
D007457:Iodine Radioisotopes; D014980:Xenon Radioisotopes; D007336:Insulin, Isophane