Acromegaly first diagnosed in pregnancy: the role of bromocriptine therapy.
We report a case of acromegaly diagnosed in the second trimester of pregnancy. Bromocriptine (7.5 mg per day) corrected visual field defects and suppressed prolactin secretion but did not reduce fasting growth hormone levels. We propose that suppression of physiologic lactotroph hyperplasia by bromocriptine may permit noninvasive management of pituitary adenomas during pregnancy.
Yap
A S
AS
Department of Endocrinology, Royal Brisbane Hospital, Herston, Australia.
Clouston
W M
WM
Mortimer
R H
RH
Drake
R F
RF
D000172:Acromegaly / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D000236:Adenoma / Q000150:complications / Q000175:diagnosis*; D000328:Adult; D001971:Bromocriptine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000150:complications / Q000175:diagnosis*
D001971:Bromocriptine