Crystallization of blood coagulation factor XIII by an automated procedure.
Both recombinant blood coagulation factor XIII alpha-chain and factor XIII isolated from human placenta have been crystallized using a novel robotic system for the automatic screening of crystallization conditions. The monoclinic and orthorhombic crystals obtained are suitable for X-ray analysis.
Hilgenfeld
R
R
Hoechst Aktiengesellschaft, Frankfurt, FRG.
Liesum
A
A
Storm
R
R
Metzner
H J
HJ
Karges
H E
HE
D003460:Crystallization; D004792:Enzyme Precursors / Q000302:isolation & purification; D005176:Factor XIII / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D010920:Placenta / Q000201:enzymology; D011247:Pregnancy; D014961:X-Ray Diffraction
D004792:Enzyme Precursors; D005176:Factor XIII