Neuropeptide K-like immunoreactivity in human dental pulp.
Nerve fibres displaying such immunoreactivity were revealed by indirect immunofluorescence. Neuropeptide K-like immunoreactive fibres, entering the pulp within large nerve trunks, were distributed around blood vessels as well as in the stroma. Some immunoreactive fibres were also observed in the para-odontoblastic region. In view of the biological activity of neuropeptide K, it is tentatively proposed that it may act in the dental pulp as a regulatory peptide involved in neurogenic inflammation, blood flow regulation and sensory transmission.
Casasco
A
A
Istituto di Istologia ed Embriologia, University of Pavia, Italy.
Calligaro
A
A
Springall
D R
DR
Casasco
M
M
Poggi
P
P
Valentino
K L
KL
Polak
J M
JM
D001808:Blood Vessels / Q000294:innervation; D003782:Dental Pulp / Q000032:analysis* / Q000098:blood supply / Q000294:innervation; D006801:Humans; D007150:Immunohistochemistry; D009412:Nerve Fibers / Q000032:analysis / Q000648:ultrastructure; D009479:Neuropeptides / Q000032:analysis*; D015320:Tachykinins
D009479:Neuropeptides; D015320:Tachykinins; C045206:neuropeptide K