title: [Clinical evaluation of norfloxacin in children].
abstract: We administered norfloxacin (NFLX) to 16 children aged 3 to 14 year-old at the dose of 5.2 to 17.2 mg/kg/day. We evaluated the efficacy and safety of NFLX in 6 children with respiratory tract infections, 8 urinary tract infections, and 2 gastrointestinal tract infections. Efficacy rate of NFLX was 93.8% and eradicated rate was 92.9%. Any adverse effects were not observed. These results suggested that NFLX could be used safely to the children.
authors.affiliation: Department of Pediatrics, Mie University.
authors.forename: T
authors.initials: T
authors.lastname: Ihara
authors.forename: H
authors.initials: H
authors.lastname: Kawaguchi
authors.forename: M
authors.initials: M
authors.lastname: Ito
authors.forename: H
authors.initials: H
authors.lastname: Kamiya
authors.forename: M
authors.initials: M
authors.lastname: Sakurai
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001419:Bacteria / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D004352:Drug Resistance, Microbial; D004751:Enteritis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D009643:Norfloxacin / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D014552:Urinary Tract Infections / Q000188:drug therapy*
chemical_list: D009643:Norfloxacin