title: In vitro study (Rusitec) of the action of abierixin, a new ionophore antibiotic, on the end products of fermentation and the degradation of nitrogen in the rumen.
abstract: We investigated the capacity of a new ionophore antibiotic, abierixin, to modify fermentations in the rumen using a semi-continuous fermenter (Rusitec). As in the studies carried out on a "batch" fermenter (HILLAIRE et al., 1989a), abierixin failed to alter volatile fatty acids and gas productions but, in contrast, it limited the degradation of dietary nitrogen without affecting microbial synthesis. This molecule which has a low level of toxicity and is capable of improving the use of dietary proteins by ruminants, was found to be more effective when used at very low dose levels.
authors.affiliation: I.N.R.A., Centre de Recherches de Clermont-Theix, Station de Recherches sur la Nutrition des Herbivores, Ceyrat-France.
authors.forename: L
authors.initials: L
authors.lastname: Gomez
authors.forename: M C
authors.initials: MC
authors.lastname: Hillaire
authors.forename: J P
authors.initials: JP
authors.lastname: Jouany
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D005232:Fatty Acids, Volatile / Q000096:biosynthesis; D005285:Fermentation / Q000187:drug effects; D066298:In Vitro Techniques; D007476:Ionophores / Q000494:pharmacology*; D009584:Nitrogen / Q000378:metabolism*; D011714:Pyrans / Q000494:pharmacology; D012417:Rumen / Q000187:drug effects / Q000378:metabolism*; D013025:Glycine max
chemical_list: D000900:Anti-Bacterial Agents; D005232:Fatty Acids, Volatile; D007476:Ionophores; D011714:Pyrans; C047796:abierixin; D009584:Nitrogen