title: Neurologic complications of cloacogenic carcinoma.
abstract: Cloacogenic carcinoma is a rare tumor, originating from epithelium of the anal transition zone. We report a 63-yr-old man with pathologically proven cloacogenic carcinoma which caused a rapidly progressive paraparesis and changes in mental status. These were related to extramedullary deposits around the spinal cord and cauda equina and intramedullary deposits in the brain. This pattern of neural involvement with anal canal carcinoma has not been reported previously.
authors.affiliation: Department of Neurology, St. Vincent's Hospital, New York, NY.
authors.forename: M
authors.initials: M
authors.lastname: Garofalo
authors.forename: C A
authors.initials: CA
authors.lastname: Martin
authors.forename: T T
authors.initials: TT
authors.lastname: Eng
authors.forename: H
authors.initials: H
authors.lastname: Donnenfeld
authors.forename: F B
authors.initials: FB
authors.lastname: Smith
authors.forename: J C
authors.initials: JC
authors.lastname: Masdeu
mesh_terms: D001005:Anus Neoplasms / Q000473:pathology*; D002295:Carcinoma, Transitional Cell / Q000473:pathology*; D002493:Central Nervous System Diseases / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009423:Nervous System Neoplasms / Q000150:complications / Q000473:pathology / Q000556:secondary*