Possible chloroquine-induced modification of N-acetylation of isoniazid and sulphadimidine in the rat.
Nwankwo
J O
JO
Department of Biochemistry College of Medicine, University of Ibadan, Nigeria.
Garba
M A
MA
Chinje
C E
CE
Mgbojikwe
L O
LO
Emerole
G O
GO
D000107:Acetylation; D000818:Animals; D001191:Arylamine N-Acetyltransferase / Q000037:antagonists & inhibitors / Q000378:metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D002738:Chloroquine / Q000494:pharmacology*; D005260:Female; D007538:Isoniazid / Q000378:metabolism* / Q000652:urine; D008099:Liver / Q000201:enzymology; D008297:Male; D015394:Molecular Structure; D051381:Rats; D011919:Rats, Inbred Strains; D013418:Sulfamethazine / Q000378:metabolism* / Q000652:urine
D013418:Sulfamethazine; D002738:Chloroquine; D001191:Arylamine N-Acetyltransferase; D007538:Isoniazid