[Surgical experience of bronchogenic early squamous cell carcinoma detected by sputum cytology in lung cancer screening].
Eighty-one patients of roentgenologically occult lung cancer (all men, and squamous cell carcinoma) were detected by sputum cytology in lung cancer screening of "Miyagi Program". Sixty-seven patients were resected surgically, and sixty-four of them underwent absolutely curative resection. In fifty-six patients, carcinoma did not penetrate the bronchial wall, and all of them were free from lymph node involvement. In eleven patients, carcinoma penetrated the bronchial wall, and three of them were proved to have lymph node involvement. For that reason, carcinoma which did not penetrate the bronchial wall and was free from lymph node involvement, was defined as early squamous cell carcinoma. Fourty-two early squamous cell carcinoma were located on segmental or more proximal bronchi, but twelve were located on subsegmental or more peripheral bronchi. Five-year survival of fifty-six patients with early squamous cell carcinoma were 91.8%, seven of fifty-six early squamous cell carcinoma patients were multicentric, which were detected synchronously in four cases, postoperatively in two cases, and both synchronously and postoperatively in one case. Two of three postoperatively detected cases were resected surgically and alive without cancer. These results indicate the validity of surgical treatment for roentgenologically occult squamous cell carcinoma. As the most serious prognostic problem is multicentricity, careful localization of primary lesion and postoperative intensive follow-up should be considered.
Saito
Y
Y
Department of Surgery, Research Institute for Chest Diseases and Cancer, Tohoku University, Sendai, Japan.
Nagamoto
N
N
Sagawa
M
M
Takahashi
S
S
Usuda
K
K
Fujimura
S
S
Nakada
T
T
Imai
T
T
Hashimoto
K
K
Ohkuda
K
K
D000368:Aged; D000369:Aged, 80 and over; D002283:Carcinoma, Bronchogenic / Q000517:prevention & control / Q000601:surgery*; D002294:Carcinoma, Squamous Cell / Q000517:prevention & control / Q000601:surgery*; D006801:Humans; D008175:Lung Neoplasms / Q000517:prevention & control / Q000601:surgery*; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D013183:Sputum / Q000166:cytology*