[Differences in the expression of blood group antigens A and B in carcinoma of the stomach in relation to Laurén's classification].
Expression of blood group antigens A and B was studied in a group of 48 gastric carcinomas (classified according to Laurén as intestinal and diffuse types respectively) by monoclonal antibodies in an indirect immunoperoxidase method. Results could be summarized as followings: 1. Significant difference concerned the expression of blood group antigens A and AB. Intestinal type was characterized by striking heterogeneity of expression and more pronounced deletion of antigens. Diffuse type had a homogenous expression and a distinctly smaller deletion. 2. Supranuclear immunoreactivity with monoclonal antibody HE 10 in intestinal type carcinoma may have a prognostic importance. This expression could not be observed in diffuse type carcinoma.
Tichý
M
M
Katedra patologické anatomie LFUP, Olomouc.
Jansa
P
P
Vanák
J
J
Tichá
V
V
D000017:ABO Blood-Group System; D000230:Adenocarcinoma / Q000097:blood* / Q000145:classification / Q000276:immunology; D000911:Antibodies, Monoclonal; D004912:Erythrocytes / Q000276:immunology; D006801:Humans; D013274:Stomach Neoplasms / Q000097:blood* / Q000145:classification / Q000276:immunology
D000017:ABO Blood-Group System; D000911:Antibodies, Monoclonal
Rozdíly v expresi krevních skupinových antigenů A a B v karcinomu zaludku s prihlédnutím k Laurénovĕ klasifikaci.