title: The structure of tautomycetin, a dialkylmaleic anhydride antibiotic.
abstract: The chemical structure of tautomycetin (C33H50O10) was determined by chemical degradation and spectroscopic evidence. Tautomycetin exists in methanol-buffer solution (1% diethylamine-formic acid, pH 7.3) as an equilibrium mixture of a 2,3-dialkylmaleic anhydride and its dicarboxylic acid. The structure of tautomycetin is similar to tautomycin in many respects.
authors.affiliation: Antibiotics Laboratory, RIKEN (The Institute of Physical and Chemical Research), Saitama, Japan.
authors.forename: X C
authors.initials: XC
authors.lastname: Cheng
authors.forename: M
authors.initials: M
authors.lastname: Ubukata
authors.forename: K
authors.initials: K
authors.lastname: Isono
mesh_terms: D000107:Acetylation; D000935:Antifungal Agents / Q000032:analysis* / Q000378:metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D004952:Esters; D005663:Furans; D006868:Hydrolysis; D008055:Lipids; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000935:Antifungal Agents; D004952:Esters; D005663:Furans; D008055:Lipids; C058744:tautomycetin