Tm(DOTP)5-: a 23Na+ shift agent for perfused rat hearts.
Tm(DOTP)5-, the thulium(III) complex of 1,4,7,10-tetraazacyclododecane-N,N',N',N'''-tetra(methylenephos p hon ate), is introduced as a 23Na+ shift agent for use in discrimination of the NMR resonances of intra- and extracellular 23Na+ ions in perfused rat hearts. The novel shift agent is directly compared to the widely used Dy(TTHA)3- (dysprosium(III) triethylenetetraminehexaacetate).
Buster
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DC
Department of Chemistry, University of Texas, Dallas, Richardson 75083-0688.
Castro
M M
MM
Geraldes
C F
CF
Malloy
C R
CR
Sherry
A D
AD
Siemers
T C
TC
D000818:Animals; D006321:Heart; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D009206:Myocardium / Q000032:analysis*; D010080:Oxazoles; D010477:Perfusion; D011744:Pyrimidinones; D051381:Rats; D012964:Sodium / Q000032:analysis*; D013932:Thulium
D007202:Indicators and Reagents; D010080:Oxazoles; D011744:Pyrimidinones; C063359:2,3-dihydro-5H-oxazolo(3,2-a)thieno(3,2-d)pyrimidin-5-one; D013932:Thulium; D012964:Sodium