Influenza vaccine and anticoagulation control in patients receiving warfarin.
The effects of a trivalent split virion influenza vaccine on anticoagulation control were prospectively evaluated in a sample of well-controlled warfarin recipients. Vaccine-induced changes in prothrombin time ratios were not detected during one month of follow-up after immunisation. The results are supported by the findings of other studies conducted in this country and the USA, which have all refuted the conclusions of early reports that suggested a possible interaction between warfarin and influenza vaccine.
Arnold
W S
WS
Medical Affairs, Meriuex UK Ltd, Maidenhead, Berks.
Mehta
M K
MK
Roberts
J S
JS
D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007252:Influenza Vaccines / Q000009:adverse effects / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D011517:Prothrombin Time; D014859:Warfarin / Q000378:metabolism*
D007252:Influenza Vaccines; D014859:Warfarin