[An immunologic study of patients with epilepsy].
Eight indices of the immunological function were studied in 246 adult epileptic patients with 100 normal adults as control, it was found that mean contents of blood IgA, and IgM decreased, that of complement C3 increased, and the rates of lymphocyte transformation as well as rosette formation decreased in this group of epileptic patients. The decrease of IgA was related to the types of seizures and the taking of antiepileptic drugs. Suggesting that immunological abnormality did exist in the epileptic patients. The mean content of circulating immune complexes. (CIC) had a negative correlation with the period of time after seizures. It was much higher than that of the controls within the first 3 days after the seizures with its highest levels reached on the first day. Suggesting that immune reactions took part in the process of seizure episodes.
Xie
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Department of Neurology, Affiliated Hospital of Qingdao medical college.
D000293:Adolescent; D000328:Adult; D000936:Antigen-Antibody Complex / Q000097:blood; D003176:Complement C3 / Q000032:analysis; D004827:Epilepsy / Q000276:immunology*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008297:Male; D008875:Middle Aged
D000936:Antigen-Antibody Complex; D003176:Complement C3; D007070:Immunoglobulin A; D007075:Immunoglobulin M