[Fecal intestinal flora in patients with colon adenoma and colon cancer].
Fecal intestinal flora in patients with colon adenoma showed significant decrease of Bifidobacterium. A tendency of decrease of Bifidobacterium and increase of Clostridium-other was shown in adenomas with higher degree atypia, but no definite tendency could be found concerning its size. Compared with the control group, patients with colon cancer showed significant increase of Clostridium-other and decrease tendency of Bifidobacterium which was not relevant to its percentage of total circum ference involved by the cancer. From the above findings, it is suggested that tumor growth or malignant transformation has relation to Bifidobacterium and Clostridium-other.
Kubota
Y
Y
Fourth Department of Internal Medicine, Tokyo Medical College.
D000236:Adenoma / Q000382:microbiology* / Q000473:pathology; D000368:Aged; D001419:Bacteria / Q000302:isolation & purification; D001644:Bifidobacterium / Q000302:isolation & purification; D003013:Clostridium / Q000302:isolation & purification; D003110:Colonic Neoplasms / Q000382:microbiology* / Q000473:pathology; D005243:Feces / Q000382:microbiology*; D005260:Female; D006801:Humans; D007422:Intestines / Q000382:microbiology*; D008297:Male; D008875:Middle Aged