title: Complement C2, C3, C4 and factor B allele distribution in the Gipsy population in Hungary.
abstract: Allotype frequencies of four complement proteins (C3, C2, factor B, and C4) were tested in 150 healthy Hungarian and 126 healthy Gipsy individuals living in Hungary. We observed significant differences between the two ethnic groups in the incidence of C3*F, Bf*F, C4A*Q0, C4A*3, C4B*1 and C4B*2 allotypes. Bf*F occurred more frequently among Gipsies, while frequencies for the other three allotypes was lower in this group than in Hungarians. The similarities in the allotype frequencies of C3 and Bf among Gipsy and Gaddis (India) populations supports the Indian origin of the former ethnic group.
authors.affiliation: National Institute of Haematology and Blood Transfusion, Budapest, Hungary.
authors.forename: J
authors.initials: J
authors.lastname: Kramer
authors.forename: T
authors.initials: T
authors.lastname: Kassai
authors.forename: T
authors.initials: T
authors.lastname: Tauszik
authors.forename: G
authors.initials: G
authors.lastname: Füst
mesh_terms: D000328:Adult; D000483:Alleles; D003175:Complement C2 / Q000235:genetics*; D003176:Complement C3 / Q000235:genetics*; D003181:Complement C4 / Q000235:genetics*; D011415:Complement Factor B / Q000235:genetics*; D004792:Enzyme Precursors / Q000235:genetics*; D005006:Ethnicity; D005260:Female; D005787:Gene Frequency; D006801:Humans; D006814:Hungary; D008297:Male; D006178:Romani People / Q000235:genetics*
chemical_list: D003175:Complement C2; D003176:Complement C3; D003181:Complement C4; D004792:Enzyme Precursors; D011415:Complement Factor B