Evaluation of topical povidone-iodine versus gentamycin in staphylococcus coagulase positive corneal ulcers--an experimental study.
Povidone iodine was found highly effective in controlling the infection and reducing the period of morbidity caused by experimentally produced staphylococcal coagulase positive corneal ulcers in 50 eyes of rabbits in comparison to Gentamycin sulphate. Povidone-iodine was also found to be safe, without any adverse reaction. Hence it can be considered for use in human beings for effective control of corneal infections.
Sharma
L G
LG
Department of Ophthalmology, JLN Medical College, Ajmer.
Goyal
J K
JK
Sharma
U
U
Chandak
G K
GK
Nepalia
L K
LK
D000818:Animals; D003030:Coagulase / Q000096:biosynthesis; D003320:Corneal Ulcer / Q000188:drug therapy*; D004341:Drug Evaluation; D005839:Gentamicins / Q000627:therapeutic use*; D011205:Povidone; D011206:Povidone-Iodine / Q000627:therapeutic use*; D011817:Rabbits; D013203:Staphylococcal Infections / Q000188:drug therapy*; D013210:Staphylococcus / Q000201:enzymology
D003030:Coagulase; D005839:Gentamicins; D011206:Povidone-Iodine; D011205:Povidone