title: Perinatal glucose metabolism as an indicator for stress and hypoxia during different forms of delivery.
abstract: In 82 term newborns divided into three groups (spontaneous delivery, caesarean section and vacuum extraction) we investigated umbilical artery pH, artery and vein glucose levels and calculated the veno-arterial difference of glucose. The three groups showed significant differences of artery and vein glucose levels. The highest umbilical artery (UA) and umbilical vein (UV) glucose levels were found after vacuum extractions (n = 13, UA: 98 mg/dl, UV: 104 mg/dl), the lowest levels were present in the group of caesarean section (n = 16, UA: 52 mg/dl, UV: 65 mg/dl). After spontaneous deliveries the intermediate levels were observed (n = 55, UA: 70 mg/dl, UV: 84 mg/dl). The mean of UA-UV-glucose difference was low after vacuum extractions and statistically different from the values after caesarean section and spontaneous deliveries. The mean of UA-pH did not show statistically significant differences in the three groups. The regression analysis between UA-pH and UA-UV-glucose difference revealed a highly significant dependency in the group of caesarean section (p less than 0.01) but no dependency after vacuum extraction. Significant dependency was also found in the group of spontaneous delivery (p less than 0.05).
authors.affiliation: Department of Pediatrics, University of Kiel, West-Germany.
authors.forename: W
authors.initials: W
authors.lastname: Nikischin
authors.forename: D
authors.initials: D
authors.lastname: Weisner
authors.forename: H D
authors.initials: HD
authors.lastname: Oldigs
mesh_terms: D000704:Analysis of Variance; D001786:Blood Glucose / Q000378:metabolism*; D002585:Cesarean Section; D036861:Delivery, Obstetric; D005260:Female; D005316:Fetal Distress / Q000097:blood / Q000175:diagnosis*; D005311:Fetal Hypoxia / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D014469:Umbilical Arteries / Q000378:metabolism; D014471:Umbilical Veins / Q000378:metabolism; D014620:Vacuum Extraction, Obstetrical
chemical_list: D001786:Blood Glucose