Nonmucinous, glycogen-poor cystadenocarcinoma of the pancreas.
True cystic neoplasms of the pancreas generally have mucinous, glycogen-rich, or acinar-type-cyst-lining epithelium. A malignant polycystic pancreatic neoplasm in a 74-year-old black woman whose cyst-lining epithelium had none of the above-cited attributes and thus appears to represent an exception is described. The primary tumor was a large, encapsulated mass whose cysts contained watery fluid. Basically, two types of epithelium lined the cysts: a single layered, low-grade malignant-appearing type and a proliferative, overtly malignant-appearing pseudostratified and papillary type. Oncocytic metaplasia, canaliculi, and microvilli were ultrastructural features.
Friedman
H D
HD
Department of Pathology, State University of New York Health Science Center, Syracuse 13210.
D000368:Aged; D003536:Cystadenocarcinoma / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006003:Glycogen / Q000032:analysis*; D006801:Humans; D007150:Immunohistochemistry; D009077:Mucins / Q000032:analysis*; D010190:Pancreatic Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure
D009077:Mucins; D006003:Glycogen