title: Chronic postoperative endophthalmitis from Staphylococcus aureus.
abstract: We recently treated a patient with chronic postoperative endophthalmitis caused by Staphylococcus aureus, which usually presents with a fulminant clinical course. Because of the chronic course, the initial treatment was high dose steroids followed by lensectomy and vitrectomy. However, this was not effective, and intravitreal antibiotics and steroids were ultimately required. We now recommend that in patients with chronic postoperative inflammation unresponsive to high dose steroids, intraocular cultures followed by injection of intraocular antibiotics be considered.
authors.affiliation: Department of Ophthalmology, New York Eye and Ear Infirmary, New York.
authors.forename: J A
authors.initials: JA
authors.lastname: Seedor
authors.forename: R S
authors.initials: RS
authors.lastname: Koplin
authors.forename: M
authors.initials: M
authors.lastname: Shah
authors.forename: E E
authors.initials: EE
authors.lastname: Almeda
authors.forename: H D
authors.initials: HD
authors.lastname: Perry
mesh_terms: D001082:Aqueous Humor / Q000382:microbiology; D002437:Cefazolin / Q000627:therapeutic use; D002908:Chronic Disease; D009877:Endophthalmitis / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D005260:Female; D006801:Humans; D007249:Inflammation / Q000188:drug therapy / Q000209:etiology; D007910:Lenses, Intraocular / Q000009:adverse effects*; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D014821:Vitrectomy; D014822:Vitreous Body / Q000382:microbiology
chemical_list: D011239:Prednisolone; D002437:Cefazolin