title: Topical prostaglandin E2 gel for cervical ripening and closure of the ductus arteriosus in the newborn.
abstract: The closure time of the ductus arteriosus was investigated in 29 full term babies born vaginally after induction with prostaglandin E2 and in 22 controls. Serial Doppler echocardiography studies showed a significantly prolonged closure time in babies induced by prostaglandin E2. Whether the difference is related to changes in fetal prostaglandin E2 concentration remains to be established.
authors.affiliation: Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin.
authors.forename: R Y
authors.initials: RY
authors.lastname: Sung
authors.forename: J A
authors.initials: JA
authors.lastname: Yin
authors.forename: E P
authors.initials: EP
authors.lastname: Loong
authors.forename: T F
authors.initials: TF
authors.lastname: Fok
authors.forename: J
authors.initials: J
authors.lastname: Lau
mesh_terms: D000287:Administration, Topical; D015232:Dinoprostone / Q000008:administration & dosage* / Q000097:blood; D004373:Ductus Arteriosus / Q000187:drug effects* / Q000502:physiology; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn; D007751:Labor, Induced; D011247:Pregnancy; D013997:Time Factors
chemical_list: D015232:Dinoprostone