Determination of diphenhydramine hydrochloride by flow injection with bromophenol blue and turbidimetric measurement.
The study of a number of diphenhydramine-dye systems was carried out in order to determine the most suitable precipitate for the turbidimetric determination of diphenhydramine using flow injection (FI). The reagent selected was Bromophenol Blue. The chemical and FI variables were optimised. The calibration graph was linear over the concentration range 50-230 p.p.m. of diphenhydramine hydrochloride. A number of interfering substances were also investigated.
Martinez Calatayud
J
J
Departamento de Quimica Analitica, Facultad de CC Quimicas, Universidad de Valencia, Spain.
Sanchez Sampedro
A
A
Navasquillo Sarrion
S
S
D001978:Bromphenol Blue; D004155:Diphenhydramine / Q000032:analysis*; D007202:Indicators and Reagents; D009391:Nephelometry and Turbidimetry
D007202:Indicators and Reagents; D001978:Bromphenol Blue; D004155:Diphenhydramine