Distinctive cataract in the Stickler syndrome.
We determined the clinical characteristics of cataract in 133 patients with the Stickler syndrome. Cataracts of various types or aphakia were found in 115 of 231 eyes (49.8%) studied. The most frequent and distinctive lesions, described as wedge and fleck cataracts, accounted for 40 of the 93 cataracts (43.0%) observed. These distinctive opacities may serve as a clinical marker for the Stickler syndrome and facilitate early diagnosis.
Seery
C M
CM
Retina Associates, Eye Research Institute, Boston, MA 02114.
Pruett
R C
RC
Liberfarb
R M
RM
Cohen
B Z
BZ
D000293:Adolescent; D000328:Adult; D000368:Aged; D001035:Aphakia / Q000453:epidemiology; D002386:Cataract / Q000453:epidemiology / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D005128:Eye Diseases / Q000235:genetics / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D013577:Syndrome