High-performance liquid chromatographic measurement of (R)-4-[3-[(2-hydroxy-2-phenethyl)amino]-3-methylbutyl]benzamide monohydrochloride (LY195448) and its p-hydroxy metabolite in human plasma and urine.
Engineer
M S
MS
Department of Medical Oncology, University of Texas, M.D. Anderson Cancer Center, Houston 77030.
Newman
R A
RA
D000970:Antineoplastic Agents / Q000097:blood* / Q000493:pharmacokinetics / Q000652:urine; D001549:Benzamides / Q000097:blood* / Q000493:pharmacokinetics / Q000652:urine; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004983:Ethanolamines / Q000097:blood* / Q000493:pharmacokinetics / Q000652:urine; D006801:Humans; D015394:Molecular Structure
D000970:Antineoplastic Agents; D001549:Benzamides; D004983:Ethanolamines; C060459:4-(3-(2-hydroxy-2-phenyl)ethylamino-3-methylbutyl)benzamide; C065163:LY 135114