Oxytoxins, bioactive molecules produced by the marine opisthobranch mollusc Oxynoe olivacea from a diet-derived precursor.
The ethereal extract of the mucous secretion from the opisthobranch mollusc Oxynoe olivacea was examined and found to contain two novel ichthyotoxic compounds, named oxytoxin 1 and 2 (1,2). The structures of 1 and 2 are closely related to the metabolites previously isolated from the alga Caulerpa prolifera. The activity of the most stable compound was studied in order to investigate the possibility of a further biological role for these metabolites, which represent an uncommon example of bioactive molecules produced in vivo from a dietary precursor.
Cimino
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Istituto per la Chimica di Molecole d'Interesse Biologico, Napoli, Italy.
Crispino
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A
Di Marzo
V
V
Gavagnin
M
M
Ros
J D
JD
D000447:Aldehydes; D000818:Animals; D004032:Diet; D056890:Eukaryota; D009682:Magnetic Resonance Spectroscopy; D008974:Mollusca / Q000032:analysis* / Q000378:metabolism; D008978:Mollusk Venoms / Q000302:isolation & purification* / Q000378:metabolism; D014118:Toxins, Biological / Q000302:isolation & purification* / Q000378:metabolism
D000447:Aldehydes; D008978:Mollusk Venoms; D014118:Toxins, Biological