[The effect of middle molecules isolated from the serum of burn patients on the state of lipid peroxidation in animal tissues].
Intensity of ascorbate-, NADPH-dependent and spontaneous lipid peroxidation were studied in mice brain and liver tissues after intravenous administration of middle molecular mass peptides, isolated from blood serum of animals with thermic burns. Positive effect of these peptides on lipid peroxidation was detected in tissues of animals with altered rate of lipid peroxidation (strong burns of 10-12% of body surface served as a biological model). The data obtained suggest that individual components of blood serum middle molecular fraction appear to exhibit the regulating effects on lipid peroxidation in animal tissues.
Tupikova
Z A
ZA
Osipovich
V K
VK
D000818:Animals; D001798:Blood Proteins / Q000302:isolation & purification / Q000502:physiology*; D001921:Brain / Q000378:metabolism; D002056:Burns / Q000097:blood*; D006801:Humans; D015227:Lipid Peroxidation; D008099:Liver / Q000378:metabolism; D008297:Male; D051379:Mice; D008970:Molecular Weight
D001798:Blood Proteins
Vliianie srednikh molekul, vydelennykh iz syvorotki krovi obozhzhennykh patsientov, na sostoianie protsessov perekisnogo okisleniia lipidov v tkaniakh zhivotnykh.