title: Deficiency of methionine synthesis enzyme activity in ascites tumor cells.
abstract: Betaine-homocysteine- and S-adenosylmethionine-homocysteine-methyltransferases which catalyze synthesis of methionine from homocysteine are absent in tumor cells such as mouse Ehrlich ascites tumor cells and rat hepatoma AH-109A ascites cells.
authors.affiliation: Department of Pathological Biochemistry, Medical Research Institute, Tokyo Medical and Dental University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Shimizu
authors.forename: M
authors.initials: M
authors.lastname: Abe
authors.forename: K
authors.initials: K
authors.lastname: Tsukada
mesh_terms: D000818:Animals; D050940:Betaine-Homocysteine S-Methyltransferase; D002286:Carcinoma, Ehrlich Tumor / Q000201:enzymology*; D002855:Chromatography, Thin Layer; D050904:Homocysteine S-Methyltransferase; D008297:Male; D008715:Methionine / Q000096:biosynthesis*; D008780:Methyltransferases / Q000378:metabolism*; D051379:Mice; D014407:Tumor Cells, Cultured
chemical_list: D008715:Methionine; D008780:Methyltransferases; D050904:Homocysteine S-Methyltransferase; D050940:Betaine-Homocysteine S-Methyltransferase; C494549:Bhmt protein, mouse