Cytochrome c oxidase depleted of subunit III: proton-pumping, respiratory control, and pH dependence of the midpoint potential of cytochrome a.
An examination of respiratory control, proton pumping, and the pH dependence of the redox potential of cytochrome a is reported for subunit III-depleted rat liver cytochrome oxidase prepared by chromatography in laurylmaltoside. The results indicate a facilitating rather than essential role for subunit III in these properties related to energy conservation.
D A
DA
Thompson
L
L
Gregory
S
S
Ferguson-Miller
D000818:Animals; D002417:Cattle; D017936:Cytochrome a Group; D003580:Cytochromes / Q000378:metabolism*; D004579:Electron Transport; D003576:Electron Transport Complex IV / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D007473:Ion Channels / Q000378:metabolism*; D008099:Liver / Q000201:enzymology; D046911:Macromolecular Substances; D009206:Myocardium / Q000201:enzymology; D010084:Oxidation-Reduction; D010101:Oxygen Consumption; D011522:Protons; D051381:Rats
D017936:Cytochrome a Group; D003580:Cytochromes; D007473:Ion Channels; D046911:Macromolecular Substances; D011522:Protons; D003576:Electron Transport Complex IV