[The hygienic evaluation of modified Alaska pollack protein based on pathomorphological research].
It has been established that daily inclusion of modified Alaska pollack protein into the rat ration as a 10% substitute of casein does not induce any changes in the body. A long term (during 12 months) feeding of rats with the rations containing 50 and 100% of Alaska pollack protein, as casein substitute, results in significant changes in the histological structure of the kidneys and liver. The data of electron microscopy enabled the authors to make a conclusion on the presence of a toxic factor in the protein product studied.
Gulich
M P
MP
Onoprienko
E N
EN
Sokolova
A G
AG
D000818:Animals; D004044:Dietary Proteins / Q000008:administration & dosage / Q000633:toxicity*; D005260:Female; D005399:Fishes; D006651:Histocytochemistry; D007413:Intestinal Mucosa / Q000378:metabolism; D007422:Intestines / Q000187:drug effects / Q000473:pathology; D007668:Kidney / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D008099:Liver / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D010179:Pancreas / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D051381:Rats; D013997:Time Factors
D004044:Dietary Proteins
Gigienicheskaia otsenka modifitsirovannogo belka mintaia na osnove patomorfologicheskikh issledovaniĭ.