Intranuclear inclusions in urinary cytology.
Twenty-one urinary cytology specimens from 16 patients showed red intranuclear inclusion bodies. The literature pertinent to these inclusions mainly suggests that lead poisoning is a cause for such inclusions. Histories were reviewed for possible causes, particularly lead poisoning, associated medications, associated illness or relationship to neoplasia. The only consistent associations found were that all the patients were women over the age of 50 and that all inclusions were found in voided urine specimens. Four slides containing inclusions were stained by acid-fast methods, with negative results. The origin of these inclusions remains unknown.
B A
BA
Rouse
L D
LD
Donaldson
J R
JR
Goellner
D000368:Aged; D002467:Cell Nucleus / Q000648:ultrastructure*; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure*; D007855:Lead Poisoning / Q000652:urine; D008875:Middle Aged; D009161:Mycobacterium / Q000166:cytology; D009369:Neoplasms / Q000652:urine; D013194:Staining and Labeling; D001749:Urinary Bladder Neoplasms / Q000652:urine; D014556:Urine / Q000166:cytology*