Two syndromes of aphasia occurring with ischemic lesions involving the left basal ganglia.
Seven aphasic patients with circumscribed left basal ganglia infarctions were investigated within the first 15 days after their strokes. Five showed transcortical motor aphasia initially. Two patients suffered from anterior chorioideal artery infarction. As this vessel does not contribute to cortical supply, cortical malfunction probably cannot account for the language deficits. Patients with infarctions in the supply area of anterior lenticulostriate arteries became fluent with frequent phonemic and semantic paraphasias resembling Wernicke's aphasia. Three of four patients showed transiently more pronounced deficits in auditory than in written-language comprehension.
Wallesch
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CW
D000293:Adolescent; D000368:Aged; D001037:Aphasia / Q000209:etiology* / Q000503:physiopathology; D001039:Aphasia, Broca / Q000209:etiology* / Q000523:psychology; D001041:Aphasia, Wernicke / Q000209:etiology* / Q000523:psychology; D001479:Basal Ganglia / Q000503:physiopathology*; D002544:Cerebral Infarction / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged