Immunological aspects of virology. WHO Working Group.
This article summarizes the conclusions of a WHO Working Group concerning progress towards an improved understanding of the mechanisms of natural and vaccine-induced immunity to viral infection in man. Particular attention is given to the role of humoral immunity, non-specific cellular and virus-specific T-cell responses, interferons and lymphokines in the immune response to virus infection. Detailed knowledge of the immune responses relevant to protection by vaccines is important for a rational approach to vaccine design. Recommendations are made for future collaborative research in immunovirology with due consideration given to the needs of the recently established WHO Vaccine Development Programme.
D006801:Humans; D007113:Immunity, Innate; D007372:Interferons / Q000276:immunology; D007694:Killer Cells, Natural / Q000276:immunology; D017955:Poliovirus / Q000472:pathogenicity; D013601:T-Lymphocytes / Q000276:immunology; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology; D014774:Virulence; D014777:Virus Diseases / Q000276:immunology*
D007372:Interferons