[Dynamics of absorption of C-14-biotin by blood cells and plasma protein binding in ontogenesis].
Age peculiarities of absorption of 14C-biotin by the blood cells and plasma proteins in vitro are studied. The phase dynamics of 14C-biotin absorption by the blood cells and binding by plasma proteins is found. The reliable ontogenetic differences in absorption of 14C-biotin by the blood cells and plasma proteins are determined. The biotin-binding in vitro by the blood cells and plasma proteins decreases and becomes slower in old rats as compared with young ones.
El'kina
V A
VA
Rozanov
A Ia
AIa
D000042:Absorption; D000367:Age Factors; D000818:Animals; D001710:Biotin / Q000097:blood* / Q000493:pharmacokinetics; D001798:Blood Proteins / Q000378:metabolism*; D002250:Carbon Radioisotopes; D004912:Erythrocytes / Q000378:metabolism*; D066298:In Vitro Techniques; D007962:Leukocytes / Q000378:metabolism*; D008297:Male; D011485:Protein Binding; D051381:Rats; D011919:Rats, Inbred Strains
D001798:Blood Proteins; D002250:Carbon Radioisotopes; D001710:Biotin
Dinamika pogloshcheniia 14C-biotina kletkami krovi i sviazyvanie belkami plazmy v ontogeneze.