[Immunochemical study of estrogen-binding alpha-globulin in the tissues and blood serum of cancer patients].
EBA distribution in tumour and normal tissues was investigated using immunochemical method. The antigen was found in spleen, kidney and mammary gland extracts, as well as in the extracts of the malignant stomach tissue, throat, kidney, urinary bladder, testicles, i.e. this antigen can be secreted into blood in some forms of malignant neoplasia and is, consequently, a tumour-associated antigen. Further investigations will show, if this protein can be used for the diagnosis of malignant diseases.
Mis'kova
V I
VI
Pchelkina
Z M
ZM
Terent'ev
A A
AA
Tatarinov
Iu S
IuS
D000510:Alpha-Globulins / Q000032:analysis* / Q000276:immunology / Q000302:isolation & purification; D000941:Antigens / Q000032:analysis* / Q000276:immunology / Q000302:isolation & purification; D002846:Chromatography, Affinity; D004967:Estrogens / Q000032:analysis / Q000276:immunology* / Q000302:isolation & purification; D005260:Female; D006801:Humans; D007120:Immunochemistry; D005779:Immunodiffusion; D008297:Male; D009369:Neoplasms / Q000276:immunology*
D000510:Alpha-Globulins; D000941:Antigens; D004967:Estrogens
Immunokhimicheskoe izuchenie éstrogensviazyvaiushchego al'fa-globulina v tkaniakh i syvorotke krovi onkologicheskikh bol'nykh.