[The specificity of so-called "smoker cells" in lung tissue].
A simple test for demonstration of smoker cells was verified on bronchoalveolar lavage (BAL) and cytological smears of lung tissue. Alveolar macrophages exhibit in 81% (BAL) respectively 86% (surgical material) of the smokers with Fettrot 7B a red colouring of the cytoplasm. Only few non-smokers show a positive reaction for smoker cells. In ex-smokers this positive reaction disappears after 7 month. We conclude, that this method is very sensitive but not absolutely specific for detecting smokers with a simple cytological test.
Forschungsinstitut für Lungenkrankheiten und Tuberkulose, Berlin-Buch, DDR.
H
H
Eckert
C
C
Engelmann
U
U
Unger
D000328:Adult; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008264:Macrophages / Q000473:pathology*; D008297:Male; D008856:Microscopy, Fluorescence; D011650:Pulmonary Alveoli / Q000473:pathology*; D012907:Smoking / Q000473:pathology* / Q000628:therapy
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