Peptidylarginine deiminase in rat and mouse hemopoietic cells.
Peptidylarginine (protein-L-arginine) deiminase activities have been demonstrated in extracts of rat and mouse peritoneal macrophages, bone marrow cells, splenic adherent cells, neutrophils, and mouse monocyte/macrophage cell lines. The enzyme in these cells is indistinguishable from the skeletal muscle enzyme with respect to immunochemical properties.
Department of Biochemistry, Tokyo Metropolitan Institute of Gerontology, Itabashiku, Tokyo.
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Nagata
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Senshu
D000641:Ammonia / Q000378:metabolism; D000818:Animals; D001120:Arginine / Q000031:analogs & derivatives / Q000378:metabolism; D015153:Blotting, Western; D001853:Bone Marrow / Q000201:enzymology; D001854:Bone Marrow Cells; D002956:Citrulline / Q000378:metabolism; D005260:Female; D006867:Hydrolases / Q000378:metabolism*; D007163:Immunosorbent Techniques; D008264:Macrophages / Q000201:enzymology*; D051379:Mice; D008810:Mice, Inbred C57BL; D009000:Monocytes / Q000201:enzymology*; D009504:Neutrophils / Q000201:enzymology*; D010529:Peritoneal Cavity / Q000166:cytology; D000080002:Protein-Arginine Deiminase Type 4; D000076342:Protein-Arginine Deiminases; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000166:cytology* / Q000201:enzymology
D002956:Citrulline; D000641:Ammonia; D001120:Arginine; C009727:benzoylarginine ethyl ester; D006867:Hydrolases; D000080002:Protein-Arginine Deiminase Type 4; D000076342:Protein-Arginine Deiminases; C552151:peptidylarginine deiminase 4, mouse