False-positive amniotic fluid acetylcholinesterase results: the need for a multifacet approach to the prenatal diagnosis of neural tube defects.
Two cases are presented with false-positive amniotic fluid alpha-fetoprotein and acetylcholinesterase results for the prenatal diagnosis of neural tube defects. Stage II ultrasound revealed no lesions of the fetal spine in both cases. The alpha-fetoprotein and acetylcholinesterase results returned to normal on subsequent taps. Both pregnancies resulted in normal outcomes. A protocol is presented for managing pregnancies with abnormal alpha-fetoprotein and acetylcholinesterase results.
Lee
J E
JE
Ng
W G
WG
Falk
R E
RE
Alfi
O
O
Lopez
L
L
Platt
L D
LD
D000110:Acetylcholinesterase / Q000032:analysis*; D000328:Adult; D000653:Amniotic Fluid / Q000032:analysis*; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D009436:Neural Tube Defects / Q000175:diagnosis*; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods*; D014463:Ultrasonography; D000509:alpha-Fetoproteins / Q000032:analysis*
D000509:alpha-Fetoproteins; D000110:Acetylcholinesterase