Structural variations in actins. A study of the immunological reactivity of the N-terminal region.
The antigenicity of the N-terminal region of skeletal-muscle actin was analysed. Two epitopes, corresponding to the 1-7 and 18-28 sequences, were determined. The antibodies specific for the first epitope discriminate skeletal-muscle actin from cardiac-muscle and smooth-muscle actins. The antibodies specific for the second epitope interact with all the actins tested, ranging from invertebrate to higher-vertebrate actins.
Roustan
C
C
Benyamin
Y
Y
Boyer
M
M
Cavadore
J C
JC
D000199:Actins / Q000276:immunology*; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D000906:Antibodies / Q000276:immunology; D004591:Electrophoresis, Polyacrylamide Gel; D004797:Enzyme-Linked Immunosorbent Assay; D000939:Epitopes; D009131:Muscle, Smooth, Vascular / Q000276:immunology; D009132:Muscles / Q000276:immunology*; D010446:Peptide Fragments / Q000276:immunology; D013045:Species Specificity
D000199:Actins; D000596:Amino Acids; D000906:Antibodies; D000939:Epitopes; D010446:Peptide Fragments