[Clinical evaluation of CA 19-9, TPA, IAP and 5'-NPD-V as tumor markers of hepatocellular, bile duct and pancreas carcinoma].
The serum level of CA 19-9 elevated exponentially in gastrointestinal carcinoma and the specificity of CA 19-9 was extraordinarily high. The sensitivity of CA 19-9 to pancreas, bile duct, hepatocellular and metastatic liver carcinoma was 75%, 79%, 22%, and 82% each. TPA seems to be useful as a screening tumor maker of gastrointestinal carcinoma, because the sensitivity was very high (84%) in every gastrointestinal carcinoma. IAP increased in pancreas and bile duct carcinoma and reflected immunological status of tumor bearing host. 5'-NPD-V was useful tumor marker not only of hepatocellular carcinoma but also pancreas and bile duct carcinoma.
Takahashi
H
H
Miyazaki
H
H
Deura
M
M
Shimizu
Y
Y
Asukata
I
I
Kameda
H
H
D000951:Antigens, Neoplasm / Q000032:analysis*; D015295:Antigens, Tumor-Associated, Carbohydrate; D001650:Bile Duct Neoplasms / Q000175:diagnosis*; D002272:Carcinoembryonic Antigen / Q000032:analysis; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis*; D005293:Ferritins / Q000097:blood; D006801:Humans; D007414:Intestinal Neoplasms / Q000175:diagnosis; D008113:Liver Neoplasms / Q000175:diagnosis*; D009363:Neoplasm Proteins / Q000097:blood*; D010190:Pancreatic Neoplasms / Q000175:diagnosis*; D010455:Peptides / Q000032:analysis*; D043264:Phosphodiesterase I; D010727:Phosphoric Diester Hydrolases / Q000097:blood*; D019396:Tissue Polypeptide Antigen; D000509:alpha-Fetoproteins / Q000032:analysis
D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate; D002272:Carcinoembryonic Antigen; D009363:Neoplasm Proteins; D010455:Peptides; D019396:Tissue Polypeptide Antigen; D000509:alpha-Fetoproteins; C030193:immunosuppressive acidic protein; D005293:Ferritins; D010727:Phosphoric Diester Hydrolases; D043264:Phosphodiesterase I