Acute leukemia in patients with breast cancer.
Symptoms related to pancytopenia were the earliest signs of acute myelogenous leukemia (AML) in two patients with breast cancer. Although some patients with breast cancer may be predisposed to AML, prolonged treatment with alkylating agents may be leukemogenic.
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HG
Taylor
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PE
Baldwin
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000601:surgery / Q000628:therapy*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000209:etiology*; D008207:Lymphatic Metastasis; D008408:Mastectomy; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D010166:Palliative Care; D010198:Pancytopenia / Q000209:etiology; D011379:Prognosis