The influence of isoprinosine (ISO) on some cell immunity parameters in mice infected with influenza viruses and in mixed viral-bacterial infections. II. Phagocytosis and bactericidal activity of granulocytes.
The influence of ISO on some stages of the phagocytosis was examined. Namely, the capacity for absorbing and intracellular killing of bacteria in animals infected with influenza viruses and with mixed, viral-bacterial infections was considered. The stimulative influence of the drug was observed. It was particularly visible with the viruses adapted to mice. The influence of the drug is probably in some way specific.
Kowalska
M
M
Denys
A
A
Szydłowska
T
T
Białek
J
J
D000818:Animals; D001770:Blood Bactericidal Activity; D006098:Granulocytes / Q000276:immunology*; D007111:Immunity, Cellular / Q000187:drug effects; D007288:Inosine / Q000031:analogs & derivatives*; D007542:Inosine Pranobex / Q000276:immunology / Q000494:pharmacology*; D051379:Mice; D008807:Mice, Inbred BALB C; D009975:Orthomyxoviridae / Q000472:pathogenicity*; D010529:Peritoneal Cavity / Q000166:cytology; D010587:Phagocytosis / Q000187:drug effects*; D051381:Rats; D013203:Staphylococcal Infections / Q000503:physiopathology; D013211:Staphylococcus aureus
D007288:Inosine; D007542:Inosine Pranobex