Lack of specific placental abnormality associated with cocaine use.
Detailed gross and histologic examinations were performed on 13 placentas from pregnancies complicated by maternal cocaine use. There were no characteristic changes in placental morphologic features that would explain the increased morbidity associated with cocaine use. It is likely that cocaine exerts its deleterious effects through acute or chronic pathophysiologic changes rather than alterations in placental architecture.
Department of Reproductive Medicine, University of California, San Diego 92123.
W M
WM
Gilbert
C M
CM
Lafferty
K
K
Benirschke
R
R
Resnik
D002821:Chorioamnionitis / Q000473:pathology; D003042:Cocaine; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D010920:Placenta / Q000473:pathology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000473:pathology*; D011256:Pregnancy Outcome; D019966:Substance-Related Disorders / Q000473:pathology*
D003042:Cocaine