Primary structure of the alpha-subunit of bovine adenylate cyclase-inhibiting G-protein deduced from the cDNA sequence.
The primary structure of the alpha-subunit of the adenylate cyclase-inhibiting G-protein (Gi) has been deduced from the nucleotide sequence of cloned DNA complementary to the bovine cerebral mRNA encoding the polypeptide. A much higher degree of amino acid sequence homology is observed between the alpha-subunits of Gi and transducin (68%) than between those of Gi and the adenylate cyclase-stimulating G-protein (Gs) (43%) or between those of transducin and Gs (42%).
Nukada
T
T
Tanabe
T
T
Takahashi
H
H
Noda
M
M
Haga
K
K
Haga
T
T
Ichiyama
A
A
Kanagawa
K
K
Hiranaga
M
M
Matsuo
D000067956:Adenylyl Cyclase Inhibitors; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D001923:Brain Chemistry; D002417:Cattle; D004247:DNA; D004274:DNA, Recombinant; D019204:GTP-Binding Proteins / Q000235:genetics*; D008565:Membrane Proteins / Q000235:genetics; D009693:Nucleic Acid Hybridization; D010446:Peptide Fragments; D011061:Poly A / Q000235:genetics; D012313:RNA / Q000235:genetics; D012333:RNA, Messenger; D015293:Transducin
D000067956:Adenylyl Cyclase Inhibitors; D004274:DNA, Recombinant; D008565:Membrane Proteins; D010446:Peptide Fragments; D012333:RNA, Messenger; D011061:Poly A; D012313:RNA; D004247:DNA; D019204:GTP-Binding Proteins; D015293:Transducin