[Histology and immunopathology of colonic carcinoma].
The correlation among lymphoid cell infiltration (LI), cell-mediated immunity and immunoglobulin-containing cells distribution in the colon cancer was studied in resected materials of 136 patients with colonic cancer. The results were as follows: 1) LI of the colon cancer tended to be found more commonly in patients with colonic cancer in clinical early stage than advanced stage. 2) The cumulative 5-year survival rate in patients with positive LI was longer than that in the patients with negative or normal LI. 3) In colonic cancer patients with the better prognosis, IgA-containing cells were distributed around the tumor tissues more abundantly than that in the poor ones. 4) These results suggest that the IgA system somewhat participates in cancer immunity.
Department of Surgery, Kariya Toyota General Hospital, Kanjya, Japan.
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S
Usami
M
M
Sato
K
K
Matsumoto
K
K
Nishiwaki
T
T
Ohkubo
H
H
Kotani
J
J
Yura
D003110:Colonic Neoplasms / Q000276:immunology / Q000401:mortality / Q000473:pathology*; D006801:Humans; D007111:Immunity, Cellular; D007070:Immunoglobulin A / Q000032:analysis; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000276:immunology; D011379:Prognosis
D007070:Immunoglobulin A