A case of subungual amelanotic malignant melanoma: an electron microscopic study of aberrant melanosomes.
A 68-year-old woman with amelanotic malignant melanoma (AMM) of her left thumbnail bed was reported. The tumor cells were positive with S-100 protein. Electron microscopic findings revealed the presence of typical melanosomes and a variety of aberrant melanosomes within the tumor cells, obviously different from the results for common malignant melanoma.
Department of Dermatology, Iwate Medical University School of Medicine, Morioka Iwate, Japan.
M
M
Matsuta
I
I
Segawa
T
T
Akasaka
S
S
Kon
T
T
Nara
S
S
Minato
D000368:Aged; D005260:Female; D006801:Humans; D008544:Melanocytes / Q000473:pathology / Q000648:ultrastructure; D008545:Melanoma / Q000473:pathology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D009262:Nails; D012878:Skin Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D013933:Thumb