Sudden death from choroid plexus vascular malformation hemorrhage: case report and review of the literature.
A case of primary intraventricular hemorrhage in a previously healthy 13-year-old boy due to rupture of a choroid plexus vascular malformation is described. Review of the literature reveals that individuals with choroid plexus malformations usually present under age 40 with serious neurological symptoms. Sudden death, however, is an unusual outcome. This case and literature review illustrate the importance of early clinical recognition and surgical intervention. Choroid plexus should be microscopically examined at autopsy in any individual in which the cause of intracerebral hemorrhage is not clear, since the gross recognition of choroid plexus vascular malformations may be quite difficult.
van Rybroek
J J
JJ
Department of Pathology, University of Iowa College of Medicine, Iowa City 52242.
Moore
S A
SA
D000293:Adolescent; D002543:Cerebral Hemorrhage / Q000150:complications* / Q000209:etiology / Q000473:pathology; D002552:Cerebral Ventricles / Q000473:pathology; D002831:Choroid Plexus / Q000002:abnormalities*; D003645:Death, Sudden / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008854:Microscopy, Electron