Specific effect of the amount of dietary fat on esterase-1 (ES-1) activity of rat plasma.
The question addressed is whether the amount of dietary fat rather than that of carbohydrates or protein affects esterase-1 (ES-1) activity in plasma of rats. For this purpose, the effects on plasma ES-1 activity of replacement of dietary fat, by isocaloric amounts of either carbohydrates or protein were studied in male rats. In rats fed high-fat diets, corn oil induced higher plasma ES-1 activities than coconut fat. Plasma ES-1 activity was decreased by a decrease in fat intake. Replacement of fat by carbohydrates produced a similar decrease of plasma ES-1 activity as did replacement of fat by protein. Replacement of carbohydrates by protein did not significantly change plasma ES-1 activity. It is concluded that the amount of fat in the diet specifically influences ES-1 activity in plasma.
Department of Laboratory Animal Science, Veterinary Faculty, State University, Utrecht, The Netherlands.
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Van Lith
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Meijer
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Van Zutphen
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Beynen
D000818:Animals; D043182:Carboxylesterase; D002265:Carboxylic Ester Hydrolases / Q000097:blood*; D004040:Dietary Carbohydrates / Q000378:metabolism; D004041:Dietary Fats / Q000008:administration & dosage / Q000378:metabolism*; D004044:Dietary Proteins / Q000378:metabolism; D004435:Eating; D008297:Male; D051381:Rats; D015430:Weight Gain
D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins; D002265:Carboxylic Ester Hydrolases; D043182:Carboxylesterase