[Multiple urothelial cancers accompanied by acquired cystic disease of the kidney in a long-term hemodialysis patient].
A 41-year-old miller undergoing hemodialysis for 9 years presented with recurrent episodes of asymptomatic gross hematuria of a 7 years' duration and left flank pain with slight fever of a four months' duration. CT scans revealed bilateral acquired cystic disease of the kidney (ACDK) and a mass (phi 4 cm) in the medial portion of the left kidney, which was angiographically a hypovascular tumor. Cystoscopic examination revealed multiple papillary tumors arising from the entire bladder wall. These findings suggested that the renal mass was a renal pelvic tumor. Bilateral nephroureterectomy with left paraaortic lymph nodes dissection and radical cystectomy were carried out, followed by urethrectomy two weeks later. Histologically, multiple papillary transitional cell carcinomas with G2 greater than G3 anaplasia were found in the left renal pelvis, the lower portion of the left ureter and the bladder. The tumors were predominantly superficial, although the renal pelvic one focally invaded into the muscular layer. Lymph node metastasis and renal cell carcinoma were not recognized. Postoperative course was uneventful with normal blood pressure, though anemia was slightly progressive. He has been free of disease for six months.
Department of Urology, Tokyo Medical and Dental University School of Medicine.
S
S
Kawakami
I
I
Fukui
K
K
Nagahama
S
S
Sumi
S
S
Takeuchi
H
H
Oshima
D000328:Adult; D002295:Carcinoma, Transitional Cell / Q000150:complications / Q000473:pathology*; D006801:Humans; D052177:Kidney Diseases, Cystic / Q000150:complications*; D007680:Kidney Neoplasms / Q000150:complications / Q000473:pathology*; D007682:Kidney Pelvis; D008297:Male; D009378:Neoplasms, Multiple Primary; D006435:Renal Dialysis; D013997:Time Factors; D014516:Ureteral Neoplasms / Q000150:complications / Q000473:pathology*; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000473:pathology*