Experimental study of lymphatic contractility and its clinical importance.
Lymphatic contractility in rats was studied, and changes in lymphatic contractility were recorded under the influence of various factors. We suggest that this contraction is not only the essential driving force in lymph drainage, but also that it plays an important role in the effect resulting from external forces. It was proved that there are alpha- and beta-receptors on the smooth muscle of the lymphatics. Under the control of neurohumoral factors, alpha and beta receptors regulate the lymphatic motion coordinately. We recommend that the lymphatics that still have contractile function be selected for lymphaticovenous anastomoses or other microlymphatic operations for treating lymphedema. Diluted epinephrine is dropped onto the local lymphatic to identify its contractile function.
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Wang
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Zhong
D000818:Animals; D003714:Denervation; D004837:Epinephrine / Q000494:pharmacology; D005260:Female; D007552:Isotonic Solutions / Q000494:pharmacology; D007717:Knee; D008196:Lymph / Q000502:physiology; D008208:Lymphatic System / Q000098:blood supply / Q000294:innervation / Q000502:physiology*; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology; D051381:Rats; D013194:Staining and Labeling
D007552:Isotonic Solutions; C010380:Locke's solution; D004837:Epinephrine