Effect of prolactin and bromocriptine administration on testicular metabolism in albino rats.
Prolactin (PRL) and bromocriptine were administered subcutaneously to adult male albino rats and their effects on testicular metabolism have been analysed. PRL enhanced the activities of testicular androgen-dependent enzymes. In contrast, bromocriptine inhibited these enzyme activities, which was correlated to the blocking of PRL release by this agent. Hence, direct participation of PRL on the testicular function was evident.
Dhananjaya Reddy
Y
Y
Govindappa
S
S
D000728:Androgens / Q000378:metabolism; D000818:Animals; D001971:Bromocriptine / Q000494:pharmacology*; D004347:Drug Interactions; D008297:Male; D011388:Prolactin / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D013737:Testis / Q000187:drug effects / Q000201:enzymology*
D000728:Androgens; D001971:Bromocriptine; D011388:Prolactin