Conception in the resistant ovary syndrome occurring during hormone replacement therapy: a report of 2 cases.
Two patients with resistant ovary syndrome are described. Both patients conceived while on hormone replacement therapy. Both women were taking the phasic preparation containing mestranol and norethisterone known as 'Menophase' (Syntex Pharmaceuticals Ltd). The possible mechanism of action of this type of hormone preparation in the induction of ovulation in patients with resistant ovary syndrome is discussed.
Jequier
A M
AM
Department of Obstetrics and Gynaecology, University of Nottingham, University Hospital, Queens Medical Centre.
D000328:Adult; D004359:Drug Therapy, Combination; D004967:Estrogens / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D005306:Fertilization; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy* / Q000503:physiopathology; D008656:Mestranol / Q000494:pharmacology / Q000627:therapeutic use*; D009640:Norethindrone / Q000494:pharmacology / Q000627:therapeutic use*; D010053:Ovary / Q000187:drug effects / Q000503:physiopathology*; D010062:Ovulation Induction; D013577:Syndrome
D004967:Estrogens; D008656:Mestranol; D009640:Norethindrone