Effects of a gonadotropin-releasing hormone agonist on sexual behavior in male rhesus monkeys (Macaca mulatta).
Low levels of sexual behavior persist in male rhesus monkeys treated with GnRH-a despite very low levels of T and gonadotropin that occur during such treatment. The behavior of male rhesus monkeys treated with GnRH-a resembles the behavior of surgically castrated male rhesus monkeys more closely than it does the behavior of reproductively quiescent males during the normal nonmating season. The normal, seasonal cessation of sexual behavior in male rhesus monkeys may result from changes in behavioral sensitivity to circulating androgens.
Division of Neurobiology, Yerkes Regional Primate Research Center, Emory University, Atlanta, Georgia.
J J
JJ
Turner
J M
JM
Copenhaver
J G
JG
Herndon
D C
DC
Collins
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives* / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D007986:Luteinizing Hormone / Q000097:blood; D008251:Macaca / Q000502:physiology*; D008253:Macaca mulatta / Q000502:physiology*; D008297:Male; D010906:Pituitary Hormone-Releasing Hormones / Q000502:physiology*; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D013739:Testosterone / Q000097:blood
D010906:Pituitary Hormone-Releasing Hormones; D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone; D007986:Luteinizing Hormone; C030741:lutrelin acetate