Branch retinal artery occlusion after excessive use of nasal spray.
A young, otherwise healthy man presented with an acute retinal artery obstruction following excessive use of oxymethazolone hydrochloride 0.5% (Afrin) nasal spray. Platelet coagulation studies indicated a platelet aggregation hypersensitivity to adenosine diphosphate and epinephrine. A predisposition for sympathomimetic drug-induced platelet fibrin embolus formation appears to be the cause of the retinal artery obstruction in this case.
Magargal
L E
LE
Sanborn
G E
GE
Donoso
L A
LA
Gonder
J R
JR
D000328:Adult; D001157:Arterial Occlusive Diseases / Q000209:etiology*; D006801:Humans; D007093:Imidazoles / Q000009:adverse effects*; D008297:Male; D014663:Nasal Decongestants / Q000008:administration & dosage / Q000009:adverse effects*; D010109:Oxymetazoline / Q000009:adverse effects*; D012161:Retinal Artery / Q000473:pathology
D007093:Imidazoles; D014663:Nasal Decongestants; D010109:Oxymetazoline