[Pathomorphological and morphometric evaluation of a model of aortic insufficiency in rabbits treated with taurine].
In 45 experimental rabbits, subjected to trans-carotid aorto-valvulotomy in a month developed a congestive heart failure. When this group of rabbits was compared to the control group of 20 animals, in the course of complete pathomorphologic, histochemical and stereomorphologic analysis the following results were obtained: potassium oroticum did not show any efficacy at all; the efficacy of taurine in a dose of 10 mg/kg was low. Its effect was both direct and indirect acting through the autonomic nervous system.
Ryff
I M
IM
Elizarova
E P
EP
Orlova
Ts R
TsR
Faron
R A
RA
Puchkova
V A
VA
Petrusenko
A N
AN
Rudzhianskaĭte
A F
AF
D000818:Animals; D001021:Aortic Valve / Q000473:pathology; D001022:Aortic Valve Insufficiency / Q000188:drug therapy* / Q000473:pathology; D006321:Heart / Q000187:drug effects / Q000503:physiopathology; D006333:Heart Failure / Q000188:drug therapy / Q000473:pathology; D006439:Hemodynamics; D008297:Male; D009206:Myocardium / Q000473:pathology; D011817:Rabbits; D013654:Taurine / Q000008:administration & dosage / Q000627:therapeutic use*
D013654:Taurine
Patomorfologicheskaia i morfometricheskaia otsenka modeli aortal'noĭ nedostatochnosti u krolikov pri lechenii taurinom.