[Pathogenesis of disorders of transparency of the optic media of the eye. VI. Transmission electron microscopy in chalcosis of the lens].
By means of transmission electron microscopy in the chalcotic lens ultrastructural changes were probed which can be divided into specific and non-specific ones. Specific findings include proliferation of vacuoles in the cytoplasm, development of oedema of lenticular fibres and dilatation of intercellular spaces. For specific findings intercellular chalcosomes in the shape of copper crystals are typical. Copper crystals are dispersed also in the cytoplasm in formations lined by the membrane. Non-specific changes in the chalcotic lens can be classified as degenerative changes in the lenticular capsule, which is divided into segments.
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Oftalmologická biofyzikální laborator, ocní klinika LF UJEP, Brno.
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D000818:Animals; D003300:Copper / Q000378:metabolism / Q000633:toxicity*; D007905:Lens Diseases / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D007908:Lens, Crystalline / Q000378:metabolism / Q000648:ultrastructure*; D008854:Microscopy, Electron; D011817:Rabbits
D003300:Copper
Patogeneze poruch transparence optického prostredí oka. VI. Transmisní elektronová mikroskopie u chalkózy cocky.