Ultrastructural features of the interferon-treated adult laryngeal papilloma.
The ultrastructural features of the interferon-treated adult laryngeal papillomas are described. Compared with untreated papillomas, no differences in ultrastructure were found by transmission electron microscopy. By scanning electron microscopy, significant alterations comprising a smooth and oedematous surface with a uniform microvilli pattern of the superficial cells were observed after interferon therapy. Our observations suggest an increased cell adhesion and maturation of epithelial cells caused by interferon.
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Bomholt
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T
Horn
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007372:Interferons / Q000627:therapeutic use*; D007822:Laryngeal Neoplasms / Q000628:therapy / Q000648:ultrastructure*; D007830:Larynx / Q000648:ultrastructure; D008297:Male; D008855:Microscopy, Electron, Scanning; D008871:Microvilli / Q000648:ultrastructure; D008875:Middle Aged; D010212:Papilloma / Q000628:therapy / Q000648:ultrastructure*
D007372:Interferons