Chlorpromazine-induced liver and bone marrow granulomas associated with agranulocytosis.
Chlorpromazine-induced liver damage is usually manifested by intrahepatic cholestasis. Hypoplastic bone marrow associated with agranulocytosis is a well-known side effect of chlorpromazine treatment. A 35-year-old woman with liver and bone marrow granulomas associated with agranulocytosis induced by chlorpromazine treatment is described.
Department of Medicine, Hadassah University Hospital, Jerusalem, Israel.
A
A
Ben-Yehuda
A
A
Bloom
G
G
Lijovetzky
D
D
Flusser
R
R
Tur-Kaspa
D000328:Adult; D000380:Agranulocytosis / Q000139:chemically induced* / Q000150:complications; D001855:Bone Marrow Diseases / Q000139:chemically induced* / Q000150:complications; D056486:Chemical and Drug Induced Liver Injury; D002746:Chlorpromazine / Q000009:adverse effects*; D005260:Female; D006099:Granuloma / Q000139:chemically induced* / Q000150:complications; D006801:Humans; D008107:Liver Diseases / Q000150:complications
D002746:Chlorpromazine