[Specific cerebral alpha 1-globulin in glial tumors].
The level of specific alpha 1-globulin (S alpha 1-GB) and autoantibodies to it was measured by the immunoenzyme method in blood serum of 160 donors and 88 neurological patients. The S alpha 1-GB level was increased most frequently in blood serum of patients with glial brain tumors. In malignant glial tumors the increased serum S alpha 1-GB level was combined with a reduced level of autoantibodies to it. The work discusses the role of the suggested immunochemical tests and the mechanisms of the increase in the S alpha 1-GB level and decrease in the level of autoantibodies to this antigen.
S K
SK
Obukhov
D000510:Alpha-Globulins / Q000032:analysis*; D001323:Autoantibodies / Q000032:analysis*; D001932:Brain Neoplasms / Q000097:blood*; D005910:Glioma / Q000097:blood*; D006801:Humans; D009419:Nerve Tissue Proteins / Q000097:blood*
D000510:Alpha-Globulins; D001323:Autoantibodies; D009419:Nerve Tissue Proteins
Izuchenie spetsificheskogo al'fa 1-globulina mozga pri glial'nykh opukholiakh.