Monoclonal antibodies specific for a tumor-associated membrane phosphoprotein in human cell hybrids.
Four monoclonal antibodies, 5/138, 5/32, BD6 and 6/266, are reported which recognize a previously described membrane associated dimeric protein of Mr = 2 X 75,000 and whose expression is correlated with malignant phenotype in HeLa-normal fibroblast hybrids.
Bicknell
D C
DC
Sutherland
D R
DR
Stanbridge
E J
EJ
Greaves
M F
MF
D000911:Antibodies, Monoclonal / Q000276:immunology*; D000918:Antibody Specificity; D000951:Antigens, Neoplasm / Q000276:immunology*; D000939:Epitopes; D006367:HeLa Cells / Q000276:immunology*; D006801:Humans; D006822:Hybrid Cells / Q000276:immunology*; D046911:Macromolecular Substances; D008565:Membrane Proteins / Q000276:immunology*; D008970:Molecular Weight; D009363:Neoplasm Proteins / Q000276:immunology; D009439:Neuraminidase; D010750:Phosphoproteins / Q000276:immunology*; D014357:Trypsin
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D000939:Epitopes; D046911:Macromolecular Substances; D008565:Membrane Proteins; D009363:Neoplasm Proteins; D010750:Phosphoproteins; D009439:Neuraminidase; D014357:Trypsin