Drug interactions involving immunologic agents. Part I. Vaccine-vaccine, vaccine-immunoglobulin, and vaccine-drug interactions.
Information about immunologic drug interactions is needed by pharmacists to make rational drug-use decisions. Previously, reports of interactions involving vaccines, immune globulins, and immunodiagnostic reagents were widely dispersed. In this two-part review article, over 50 individual and categorical interactions are described, as are dozens of vaccine-vaccine and vaccine-immunoglobulin, and vaccine-drug interactions are reviewed in this first part. Vigilance by all pharmacists is needed to detect previously unreported immunologic drug interactions and to further assess known interactions.
Pharmacy Service, U.S. Army Hospital-Bremerhaven, West Germany.
J D
JD
Grabenstein
D004347:Drug Interactions; D006801:Humans; D007136:Immunoglobulins / Q000009:adverse effects*; D014612:Vaccines / Q000009:adverse effects*
D007136:Immunoglobulins; D014612:Vaccines