5q- anomaly in lymphoid disorders.
Observations made in two patients and a review of the literature confirm the occurrence of a 5q- chromosome anomaly in lymphoproliferative disorders of both T and B cell type. Additional chromosome changes were invariably present and are of the "lymphoid" type. The chromosome morphology of the 5q- is indistinguishable from that found in myeloid disorders.
Center for Human Genetics, University of Leuven, Belgium.
S
S
Kerim
C
C
Mecucci
A
A
Cuneo
E
E
Vandenberghe
A
A
Louwagie
M
M
Stul
J L
JL
Michaux
H
H
Van Den Berghe
D000954:Antigens, Surface / Q000032:analysis; D002869:Chromosome Aberrations; D002895:Chromosomes, Human, Pair 5; D005260:Female; D015321:Gene Rearrangement; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000235:genetics*; D008875:Middle Aged
D000954:Antigens, Surface