McCune-Albright syndrome: the patterns of scintigraphic abnormalities.
This study of 22 patients with the McCune-Albright syndrome examined the scintigraphic distribution of fibrous dysplasia. The most frequently affected areas were the base of the skull (82% of patients), mandible (50%), facial bones (45%), femora (59%), and legs (64%). The least frequently affected areas included the hands (none), wrists (none), ankles (none), feet (5%), sacrum (5%), and vertebrae (9%). The distribution varied somewhat from idiopathic fibrous dysplasia but generally agreed with the distributions reported in radiographic studies of patients with the McCune-Albright Syndrome. The serum alkaline phosphatase was not an accurate predictor of the extent of fibrous dysplasia.
Pfeffer
S
S
Department of Nuclear Medicine, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892.
Molina
E
E
Feuillan
P
P
Simon
T R
TR
D001842:Bone and Bones / Q000000981:diagnostic imaging*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000000981:diagnostic imaging*; D005359:Fibrous Dysplasia, Polyostotic / Q000000981:diagnostic imaging*; D006801:Humans; D011877:Radionuclide Imaging