Mapping of different neuropeptides in the lower brainstem of the rat: with special reference to the ventral surface.
A neuropeptide map of beta-endorphin-, vasoactive intestinal peptide-, substance P-, and somatostatin-like reactive neurons and nerve fibers was made by means of immunohistochemistry. Indirect immunofluorescence was carried out in parallel to peroxidase-antiperoxidase reaction using a modified fixation technique. Special interest was directed to the superficial ventral regions of the medulla oblongata where regulative centers for respiration and circulation have been localized. The atlas presented offers a reliable tool for a precise neuromorphological localization of these neuropeptides in pharmacophysiological experiments.
Leibstein
A G
AG
Dermietzel
R
R
Willenberg
I M
IM
Pauschert
R
R
D000818:Animals; D001931:Brain Mapping; D001933:Brain Stem / Q000166:cytology / Q000378:metabolism*; D004723:Endorphins / Q000378:metabolism; D005260:Female; D005455:Fluorescent Antibody Technique; D007124:Immunoenzyme Techniques; D008297:Male; D008526:Medulla Oblongata / Q000166:cytology / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism*; D051381:Rats; D013004:Somatostatin / Q000378:metabolism; D013373:Substance P / Q000378:metabolism; D014660:Vasoactive Intestinal Peptide / Q000378:metabolism; D001615:beta-Endorphin
D004723:Endorphins; D009419:Nerve Tissue Proteins; D013373:Substance P; D014660:Vasoactive Intestinal Peptide; D013004:Somatostatin; D001615:beta-Endorphin