Psychiatric phenomena in Alzheimer's disease. IV: Disorders of behaviour.
Out of a sample of 178 patients with AD, aggression was present in 20%, wandering in 19%, binge-eating in 10%, hyperorality in 6%, urinary incontinence in 48%, and sexual disinhibition in 7%. Behavioural abnormalities were greater in those with more severe dementia. Temporallobe atrophy correlated with aggression, and widening of the third ventricle with hyperorality. Features of the Kluver-Bucy syndrome were commonly seen, but the full syndrome occurred in only one subject. Patients with at least one feature of the Kluver-Bucy syndrome had greater temporal-lobe atropy than those without any of the features.
Institute of Psychiatry, De Crespigny Park, Denmark Hill, London.
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Burns
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Jacoby
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Levy
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000374:Aggression / Q000523:psychology; D000544:Alzheimer Disease / Q000175:diagnosis / Q000523:psychology*; D001143:Arousal; D001284:Atrophy; D002540:Cerebral Cortex / Q000473:pathology; D002552:Cerebral Ventricles / Q000473:pathology; D005260:Female; D006801:Humans; D006963:Hyperphagia / Q000523:psychology; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011889:Rage; D012920:Social Behavior Disorders / Q000523:psychology*; D013577:Syndrome; D014057:Tomography, X-Ray Computed