Charcot-Marie-Tooth disease and nephropathy in a mother and daughter with a review of the literature.
We report a mother-and-child combination of Charcot-Marie-Tooth disease and nephropathy. The mother received a cadaveric renal transplant, and the daughter has heavy proteinuria with normal glomerular filtration rate. There have been 7 single case reports of both disease entities and 1 report of 3 patients which includes the only sib pair. The related literature is reviewed.
Paul
M D
MD
Department of Medicine, Memorial University of Newfoundland, St. John's, Canada.
Fernandez
D
D
Pryse-Phillips
W
W
Gault
M H
MH
D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000150:complications / Q000235:genetics; D002607:Charcot-Marie-Tooth Disease / Q000150:complications / Q000235:genetics*; D002648:Child; D003638:Deafness / Q000150:complications; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000235:genetics* / Q000473:pathology; D008297:Male; D009134:Muscular Atrophy, Spinal / Q000235:genetics*