[Study of normal human fetal and adult hemoglobins by Mössbauer spectroscopy].
Human normal fetal and adult hemoglobins were investigated by Mössbauer spectroscopy. The differences discovered in quadrupole splitting are connected with distinctions in protein molecular structures. An approximation of Mössbauer spectra of hemoglobins in supposition of nonequivalence of Fe(II) electronic structure in alpha-, beta- and gamma-subunits in tetramers was proposed. Qualitative analysis of the relationship of Fe(II) electronic structure, molecular structure of the active site and functionality of hemoglobin was carried out.
Oshtrakh
M I
MI
Semenkin
V A
VA
D005296:Ferrous Compounds / Q000032:analysis; D005319:Fetal Hemoglobin / Q000032:analysis*; D006441:Hemoglobin A / Q000032:analysis*; D006801:Humans; D010108:Oxyhemoglobins / Q000032:analysis; D013057:Spectrum Analysis / Q000379:methods
D005296:Ferrous Compounds; D010108:Oxyhemoglobins; D006441:Hemoglobin A; D005319:Fetal Hemoglobin
Issledovanie normal'nykh fetal'nogo i vzroslogo gemoglobinov cheloveka metodom messbauérovskoĭ spektroskopii.