Use of dextran to prevent intraperitoneal adhesions caused by maize starch powder.
Experimental studies in rats demonstrated that maize starch powder used as lubricant in surgical gloves induces intraperitoneal granulomatosis with formation of adhesions. The possible use of dextran 70 to minimize these adhesions was investigated. By grading the formation of adhesions, it was found that dextran given intraperitoneally reduced the extent of adhesions.
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D000818:Animals; D003911:Dextrans / Q000494:pharmacology*; D005932:Gloves, Surgical; D008153:Lubrication; D008297:Male; D010532:Peritoneal Diseases / Q000209:etiology / Q000517:prevention & control*; D011208:Powders / Q000009:adverse effects; D051381:Rats; D011919:Rats, Inbred Strains; D013213:Starch / Q000009:adverse effects*; D000267:Tissue Adhesions / Q000209:etiology / Q000517:prevention & control
D003911:Dextrans; D011208:Powders; D013213:Starch