Two false-negative responses to the ajmaline test in the Wolff-Parkinson-White syndrome.
Anterograde block in the accessory pathway with a short effective refractory period was observed after intravenous (IV) injection of 1 mg/kg of ajmaline in two patients with the Wolff-Parkinson-White syndrome. The possibility of a false-negative response to this test is discussed. Ajmaline is proposed as an emergency drug in the Wolff-Parkinson-White syndrome in the setting of atrial fibrillation with a very high ventricular rate.
Cavalli
A
A
Maggioni
A
A
Tusa
M
M
Volpi
A
A
D000328:Adult; D000368:Aged; D000404:Ajmaline / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000175:diagnosis; D004562:Electrocardiography; D005188:False Negative Reactions; D006327:Heart Block / Q000175:diagnosis; D006801:Humans; D008297:Male; D014693:Ventricular Fibrillation / Q000175:diagnosis / Q000188:drug therapy; D014927:Wolff-Parkinson-White Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology
D000404:Ajmaline