The sickle erythrocyte in double jeopardy: autoxidation and iron decompartmentalization.
Hebbel
R P
RP
University of Minnesota Medical School, Minneapolis 55455.
D000755:Anemia, Sickle Cell / Q000097:blood* / Q000188:drug therapy; D000975:Antioxidants / Q000627:therapeutic use; D002451:Cell Compartmentation / Q000502:physiology*; D004910:Erythrocyte Membrane / Q000502:physiology; D004913:Erythrocytes, Abnormal / Q000378:metabolism*; D006451:Hemoglobin, Sickle / Q000378:metabolism; D006455:Hemoglobins, Abnormal / Q000378:metabolism; D006801:Humans; D007501:Iron / Q000097:blood*; D010084:Oxidation-Reduction
D000975:Antioxidants; D006451:Hemoglobin, Sickle; D006455:Hemoglobins, Abnormal; D007501:Iron