Pathophysiology of the aging kidney.
It is the alterations in renal function associated with age that necessitate physicians treating geriatric patients to have an understanding of the fragile senescent kidney. This article examines the physiologic impact of the aging kidney on homeostasis and includes a discussion of altered pharmacodynamics occurring with impaired renal function. We also discuss the limitations of various quantitative methods of measuring renal function and present several "bedside techniques" for the assessment of renal function.
James Buchanan Brady Foundation, Department of Surgery, New York Hospital-Cornell Medical Center, New York.
B R
BR
Gilbert
E D
ED
Vaughan
D000367:Age Factors; D000368:Aged; D005919:Glomerular Filtration Rate / Q000502:physiology; D006801:Humans; D007668:Kidney / Q000098:blood supply / Q000503:physiopathology*; D007674:Kidney Diseases / Q000175:diagnosis / Q000378:metabolism / Q000503:physiopathology*; D007677:Kidney Function Tests; D010599:Pharmacokinetics; D012079:Renal Circulation / Q000502:physiology