[Animal experimental and clinical studies on the behavior of an in vitro electrically produced thrombus mass].
In the electric field the solid blood components will move to the anode because of their negative surface charge. When influenced by a direct current of constant force and duration a thrombus differing in size will develop depending on the composition of the coagulation system. This regularity could be used for diagnostic purposes. By means of experiments with animals and clinical examinations the development of the "electro-clot" is observed in vitro before and after the administration of heparin. In addition, the behaviour of the thrombus developed in vitro in the electric field is checked in patients affected with obstructive lung diseases. Here a correlation existing between the mass of the thrombus and hematocrit could be proved.
Sedlarik
K M
KM
Klöcking
H P
HP
Ursinus
K
K
Ursinus
W
W
Kirsten
D
D
D000328:Adult; D000368:Aged; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D001777:Blood Coagulation / Q000187:drug effects*; D004285:Dogs; D004329:Droperidol / Q000494:pharmacology; D004564:Electrocoagulation; D005112:Extracorporeal Circulation; D005260:Female; D005283:Fentanyl / Q000494:pharmacology; D006400:Hematocrit; D006493:Heparin / Q000494:pharmacology; D006591:Hexobarbital / Q000494:pharmacology; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011479:Protamines / Q000494:pharmacology; D011817:Rabbits; D013552:Swine
D011479:Protamines; D001285:Atropine; D006493:Heparin; D006591:Hexobarbital; D004329:Droperidol; D005283:Fentanyl
Tierexperimentelle und klinische Untersuchungen über das Verhalten der in vitro elektrisch gewonnenen Thrombusmasse.