HLA antigens in cancer of the gallbladder.
Thirty one patients with gallbladder cancer (GBC) and 32 healthy controls were typed using antisera against 12 HLA-A, 31 HLA-B, 7 HLA-C and 13 HLA-DR antigens. The DR4 frequency of 61.3% (19/31) in GBC was significantly different from that of 28.1% (9/32) in the control (p = 0.00794 by Fisher's exact test). The relative risk and the etiologic fraction were 4.0 and 0.46, respectively.
Department of Hygiene and Preventive Medicine, Niigata University School of Medicine.
M
M
Yamamoto
M
M
Haga
S
S
Takagi
K
K
Endoh
S
S
Ito
K
K
Yoshida
K
K
Kato
S
S
Akai
D000328:Adult; D000368:Aged; D005706:Gallbladder Neoplasms / Q000235:genetics / Q000276:immunology*; D005787:Gene Frequency; D006680:HLA Antigens / Q000235:genetics*; D015804:HLA-DR4 Antigen / Q000235:genetics; D006801:Humans; D008875:Middle Aged
D006680:HLA Antigens; D015804:HLA-DR4 Antigen