Magnetic resonance imaging in MELAS syndrome.
MELAS syndrome is a distinct clinical entity belonging to a group of mitochondrial encephalomyopathies characterized by the tetrad of myopathy, encephalopathy, lactic acidosis, and stroke-like episodes. Computed tomography (CT) and magnetic resonance (MR) findings are reviewed in a patient with MELAS. Serial CT studies demonstrated multiple "migrating" infarcts in various stages of evolution involving primarily the posterior temporal and occipital regions. MR was more sensitive than CT in demonstrating the number and extent of cortical lesions in this disease entity.
Department of Diagnostic Radiology and Neurology, Stanford University School of Medicine, California.
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Rosen
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S
Phillips
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D
Enzmann
D000140:Acidosis, Lactic / Q000175:diagnosis; D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D002544:Cerebral Infarction / Q000175:diagnosis / Q000000981:diagnostic imaging; D002561:Cerebrovascular Disorders / Q000175:diagnosis* / Q000000981:diagnostic imaging; D004569:Electroencephalography; D005260:Female; D006261:Headache / Q000175:diagnosis / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D009135:Muscular Diseases / Q000175:diagnosis; D012640:Seizures / Q000175:diagnosis / Q000000981:diagnostic imaging; D013577:Syndrome; D014057:Tomography, X-Ray Computed