Quinine-induced hearing loss.
Sensorineural hearing loss due to quinine therapy for malaria has frequently been mentioned in the literature but has not been a subject of research during the last decades. The global spreading of chloroquine-resistant falciparum malaria brings about an increasing use of quinine. The ototoxicity of quinine can accurately be studied with ultrahigh frequency audiometry (up to 20 kHz). The case of a 29-year-old man suffering from falciparum malaria disease who got a reversible hearing loss from quinine therapy is presented.
ENT Department, University of Amsterdam, The Netherlands.
F W
FW
Nielsen-Abbring
R M
RM
Perenboom
R J
RJ
van der Hulst
D000328:Adult; D000818:Animals; D001299:Audiometry / Q000379:methods; D006319:Hearing Loss, Sensorineural / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D008288:Malaria / Q000188:drug therapy*; D008297:Male; D010963:Plasmodium falciparum; D011803:Quinine / Q000009:adverse effects* / Q000627:therapeutic use
D011803:Quinine