Induction of the synthesis of thymidine kinase by aldosterone in the kidney of the immature male rat.
Thymidine kinase activity was studied in kidneys from immature male rats after administration of aldosterone. Kinetic studies showed that the enzyme activity reached its maximum level 24 h after aldosterone injection. That increase was specific for aldosterone and could be related to the synthesis of new molecules of enzyme.
A R
AR
Bukhari
H G
HG
Hartmann
P
P
Jouan
D000450:Aldosterone / Q000494:pharmacology*; D000818:Animals; D003513:Cycloheximide / Q000494:pharmacology; D003609:Dactinomycin / Q000494:pharmacology; D004790:Enzyme Induction / Q000187:drug effects; D004958:Estradiol / Q000494:pharmacology; D007668:Kidney / Q000201:enzymology*; D007700:Kinetics; D008297:Male; D014176:Protein Biosynthesis / Q000187:drug effects; D051381:Rats; D013937:Thymidine Kinase / Q000096:biosynthesis*; D014158:Transcription, Genetic / Q000187:drug effects
D003609:Dactinomycin; D000450:Aldosterone; D004958:Estradiol; D003513:Cycloheximide; D013937:Thymidine Kinase