Ambulant monitoring to assess the efficacy of oxybutynin chloride in patients with mixed incontinence.
Objective parameters show the efficacy of oxybutynin chloride on uninhibited detrusor behavior. In the 24-hour ambulant monitoring method, intravesical and abdominal pressure are recorded. This enables quantification of the amplitude, duration, and frequency of uninhibited detrusor contractions. It is even possible to show the efficacy of this drug objectively in patients with severe mixed incontinence.
Department of Urology, University Hospital Maastricht, Eindhoven, The Netherlands.
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van Waalwijk van Doorn
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Zwiers
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008333:Mandelic Acids / Q000627:therapeutic use*; D008991:Monitoring, Physiologic; D009119:Muscle Contraction / Q000187:drug effects; D010276:Parasympatholytics / Q000627:therapeutic use*; D011312:Pressure; D012007:Rectum / Q000503:physiopathology; D001743:Urinary Bladder / Q000503:physiopathology; D014549:Urinary Incontinence / Q000188:drug therapy*; D014550:Urinary Incontinence, Stress / Q000188:drug therapy*
D008333:Mandelic Acids; D010276:Parasympatholytics; C005419:oxybutynin