Investigation of drug-containing multiple phase emulsions.
We studied the efficiency of the formation of w/o/w emulsions as a function of composition and mixing time. We found that the concentration of emulsifier 1, the concentration and HLB of emulsifier 2, the viscosity of the oil phase and the external water phase as well as the mixing time in second step of preparing the emulsion characteristically influence the "efficiency" of emulsification and the stability of the emulsions.
Department of Pharmaceutical Technology, Albert Szent-Györgyi Medical University, Szeged, Hungary.
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Erös
J
J
Balázs
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Péter
M
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Tacsi
D002626:Chemistry, Pharmaceutical; D004355:Drug Stability; D004655:Emulsions; D009821:Oils; D004364:Pharmaceutical Preparations / Q000032:analysis; D014783:Viscosity; D014867:Water
D004655:Emulsions; D009821:Oils; D004364:Pharmaceutical Preparations; D014867:Water