Hemodynamic changes with arterial stenosis experimentally created using the sliding calipers method.
The relationship of blood pressure, blood flow and Doppler waveform to arterial stenosis was investigated in a canine model. The method of making a stenosis involved using slide calipers and the critical stenosis of the femoral artery was 75 per cent. Among the parameters from Doppler waveform; peak forward velocity, pulsatility index, acceleration and deceleration correlated well with arterial stenosis, having correlation coefficients of -0.729, -0.856, -0.824 and -0.739, respectively. The results of this method conform closely to clinical conditions with regard to progress of the occlusive process.
Second Department of Surgery, Kumamoto University School of Medicine, Japan.
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H
Yamashita
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Hayakawa
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Akagi
D000818:Animals; D001783:Blood Flow Velocity; D003251:Constriction, Pathologic / Q000503:physiopathology*; D004285:Dogs; D005263:Femoral Artery / Q000503:physiopathology*; D006439:Hemodynamics; D008433:Mathematics; D008962:Models, Theoretical; D014463:Ultrasonography