Nephrogenic diabetes insipidus and intracerebral calcification.
Three children who presented with two rare conditions, nephrogenic diabetes insipidus and intracerebral calcification, were studied. The lack of evidence for the presence of a metabolic defect other than nephrogenic diabetes insipidus suggests that it can lead to the development of intracerebral calcification. Perhaps the main risk factor is inadequate fluid intake during early infancy.
University Children's Hospital, Mainz 1, Federal Republic of Germany.
O
O
Schofer
R
R
Beetz
K
K
Kruse
C
C
Rascher
C
C
Schütz
J
J
Bohl
D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000209:etiology* / Q000473:pathology; D002114:Calcinosis / Q000209:etiology* / Q000473:pathology; D003919:Diabetes Insipidus / Q000150:complications / Q000151:congenital*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007674:Kidney Diseases / Q000503:physiopathology; D007684:Kidney Tubules / Q000503:physiopathology; D008297:Male; D012307:Risk Factors