Susceptibility pattern of bacterial isolates to lomefloxacin.
The in vitro susceptibility pattern with respect to lomefloxacin was determined in case of 1009 bacterial isolates from clinical specimens with varying susceptibility to commonly used antimicrobial agents. The MIC50 and MIC90 values of lomefloxacin for the Gram negative bacilli showed susceptibility value ranging between 0.12 to 4.0 micrograms/ml, while 90 per cent of the streptococci tested were inhibited only at 16 micrograms/ml. Lomefloxacin was comparable in activity to enoxacin and ciprofloxacin but it was more active than norfloxacin and nalidixic acid.
Lalitha
M K
MK
Department of Microbiology, Christian Medical College Hospital, Vellore, India.
Nisha
A K
AK
Bhattacharya
S S
SS
Ramamoorthy
U
U
Lal
H M
HM
D000890:Anti-Infective Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D002939:Ciprofloxacin / Q000494:pharmacology; D015365:Enoxacin / Q000494:pharmacology; D024841:Fluoroquinolones; D006801:Humans; D009268:Nalidixic Acid / Q000494:pharmacology; D009643:Norfloxacin / Q000494:pharmacology; D015363:Quinolones
D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D015363:Quinolones; D015365:Enoxacin; D009268:Nalidixic Acid; D002939:Ciprofloxacin; C053091:lomefloxacin; D009643:Norfloxacin