[Antitoxic activity of interferon preparations].
The antitoxic activity of leucocytic injection interferon I and immune interferon was shown in experimental erythrocyte hemolysis in the presence of staphylococcus alpha-toxin. The antitoxic effect was directly proportional to the interferon concentration in the medium and inversely proportional to the toxin concentration. Neutralization of the antiviral activity of leucocytic interferon did not lower its antitoxic effect. The highly purified and concentrated preparation of leucocytic injection interferon I and recombinant interferon had no antitoxic effect.
Zueva
V S
VS
Pashutin
S B
SB
Kuznetsov
V P
VP
Spivak
N Ia
NIa
Korobko
I V
IV
D004768:Enterotoxins / Q000037:antagonists & inhibitors*; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D007370:Interferon Type I / Q000494:pharmacology; D007371:Interferon-gamma / Q000494:pharmacology; D007372:Interferons / Q000276:immunology / Q000494:pharmacology*; D011994:Recombinant Proteins / Q000494:pharmacology; D013211:Staphylococcus aureus
D004768:Enterotoxins; D007136:Immunoglobulins; D007370:Interferon Type I; D011994:Recombinant Proteins; C026066:enterotoxin A, Staphylococcal; D007371:Interferon-gamma; D007372:Interferons
Antitoksicheskaia aktivnost' preparatov interferona.