Effects of acidic fibroblast growth factor and epidermal growth factor on fetal rat calvaria cell cultures.
An inhibitory effect of alkaline phosphatase (LP) activity on short and long term fetal rat calvaria cell cultures was recorded with both acidic fibroblast growth factor (aFGF) and epidermal growth factor (EGF) at a concentration of 30 ng ml-1. This inhibition was well correlated with the nodule number on long term culture, except for EGF treatment in subconfluent cell culture.
Laboratoire de Biologie-Odontologie, Université Paris 2 place Jussieu, France.
V
V
Nicolas
J R
JR
Nefussi
D
D
Barritault
N
N
Forest
D000469:Alkaline Phosphatase / Q000037:antagonists & inhibitors; D000818:Animals; D002478:Cells, Cultured; D004591:Electrophoresis, Polyacrylamide Gel; D004815:Epidermal Growth Factor / Q000494:pharmacology*; D005109:Extracellular Matrix / Q000187:drug effects / Q000201:enzymology; D005333:Fetus / Q000166:cytology; D005346:Fibroblast Growth Factors / Q000494:pharmacology*; D010012:Osteogenesis / Q000187:drug effects*; D051381:Rats; D012886:Skull / Q000166:cytology / Q000196:embryology / Q000201:enzymology
D005346:Fibroblast Growth Factors; D004815:Epidermal Growth Factor; D000469:Alkaline Phosphatase