Pattern of end growth of the fission yeast Schizosaccharomyces pombe.
The patterns of end growth of individual cells of Schizosaccharomyces pombe, wild-type cells (strain 972 h-), cells exposed to 8 mM hydroxyurea, and cdc mutants (cdc11-123 and cdc2-33), were investigated by time-lapse photomicrography. It was reconfirmed that there are three patterns of end growth: cells growing at the old end, at the new end, and at both ends from the beginning of the cell cycle. Cells that initiated growth at the old (new) end increased their growth rate at the new (old) end and became constant in their growth rate at the old (new) end when cells had their growth rate higher than a critical value: 0.08, 0.09, 0.08, and 0.11 microns/min in wild-type cells, cells exposed to hydroxyurea, cdc11-123 cells, and cdc2-33 cells, respectively. The critical value is proportional to the doubling time in length.
Miyata
H
H
Division of Biological Sciences, National Research Council of Canada, Ottawa, Ont.
Miyata
M
M
Johnson
B F
BF
D002455:Cell Division / Q000187:drug effects; D006918:Hydroxyurea / Q000494:pharmacology*; D007700:Kinetics; D009154:Mutation; D012044:Regression Analysis; D004718:Saccharomycetales / Q000254:growth & development*; D012568:Schizosaccharomyces / Q000187:drug effects / Q000235:genetics / Q000254:growth & development*
D006918:Hydroxyurea