Should ovulation be induced in women recovering from an eating disorder or who are compulsive exercisers?
The eating and exercise history of women with secondary amenorrhea and failure of ovulation using CC was studied in 14 consecutive women on a GnRH-a program. All had a history of an eating or exercise disorder. At the time of the interview, 7 women continued to have an eating or exercise disorder. There were 15 pregnancies (12 women) with 12 live births, of which 4 weighed less than 2,500 g. Infertility specialists should inquire routinely about a woman's body weight and eating and exercise behaviors, and consider treatment for these before prescribing drugs to induce ovulation.
Department of Obstetrics and Gynaecology, University of Sydney, New South Wales, Australia.
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Abraham
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Mira
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Llewellyn-Jones
D000328:Adult; D000568:Amenorrhea / Q000209:etiology; D001835:Body Weight; D002996:Clomiphene / Q000494:pharmacology / Q000627:therapeutic use; D015444:Exercise / Q000502:physiology*; D001068:Feeding and Eating Disorders / Q000150:complications / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy; D010060:Ovulation / Q000187:drug effects / Q000502:physiology; D010062:Ovulation Induction; D010906:Pituitary Hormone-Releasing Hormones / Q000502:physiology; D011247:Pregnancy; D011256:Pregnancy Outcome
D010906:Pituitary Hormone-Releasing Hormones; D002996:Clomiphene