Oxalate nephropathy in a Tibetan spaniel litter. A probable case of primary hyperoxaluria.
Severe oxalate nephropathy with end-stage kidney lesions was found in two pups of a litter of three Tibetan Spaniels. This histopathological finding strongly suggests a primary hyperoxaluria since there was no exposure to agents capable of producing secondary hyperoxaluria. Primary hyperoxaluria has not been reported as a spontaneous disease in the dog, although it is a well-known, but rare, inherited metabolic disease of man.
Department of Pathology, Norweigan College of Veterinary Medicine, Oslo.
J H
JH
Jansen
K
K
Arnesen
D000818:Animals; D004283:Dog Diseases / Q000139:chemically induced* / Q000473:pathology; D004285:Dogs; D005260:Female; D006959:Hyperoxaluria / Q000662:veterinary*; D006960:Hyperoxaluria, Primary / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary*; D008297:Male; D010070:Oxalates / Q000506:poisoning*; D019815:Oxalic Acid
D010070:Oxalates; D019815:Oxalic Acid