Increased silver stainability of metaphase chromosomes from rat hepatocytes during in vivo hepatocarcinogenesis.
Silver stainability of metaphase chromosomes was studied in hepatocytes obtained from rats exposed or not to a partial or complete carcinogenic treatment with diethylnitrosamine and phenobarbital. An increased hyperstaining is reported in the carcinogen-treated animals.
Kirsch-Volders
M
M
Deleener
A
A
Lans
M
M
de Gerlache
J
J
D000818:Animals; D002471:Cell Transformation, Neoplastic; D002875:Chromosomes / Q000032:analysis*; D004052:Diethylnitrosamine; D008113:Liver Neoplasms / Q000139:chemically induced / Q000235:genetics*; D008677:Metaphase; D010634:Phenobarbital; D051381:Rats; D012834:Silver; D013194:Staining and Labeling
D004052:Diethylnitrosamine; D012834:Silver; D010634:Phenobarbital