A potent cold autoagglutinin that recognizes type 2H determinant on red cells.
An example of an IgM (lambda) cold autoagglutinin against a Type 2H determinant of the ABO blood group system is described. The direct antiglobulin test was positive due to C3d on the patient's red cells. The antibody in the patient's serum was active at 37 degrees C, and the degree of agglutination was almost the same at 37 and 4 degrees C. It agglutinated group O red cells preferentially, but not Bombay (Oh) red cells. The specificity was determined by adsorption with synthetic oligosaccharide immunoadsorbent.
Uchikawa
M
M
Tohyama
H
H
D000017:ABO Blood-Group System; D000373:Agglutinins / Q000032:analysis*; D001323:Autoantibodies / Q000032:analysis*; D002240:Carbohydrate Sequence; D003450:Cryoglobulins; D000939:Epitopes; D005260:Female; D006388:Hemagglutinins / Q000032:analysis*; D006801:Humans; D008875:Middle Aged
D000017:ABO Blood-Group System; D000373:Agglutinins; D001323:Autoantibodies; D003450:Cryoglobulins; D000939:Epitopes; D006388:Hemagglutinins; C029443:cold agglutinins