A double-blind controlled trial of a new alpha-1 blocking drug in the treatment of bladder outflow obstruction.
Thirty-one patients with urodynamically proven bladder outflow obstruction were treated with Alfuzosin in a 3-month, double-blind, placebo-controlled study. The irritative symptoms of bladder outflow obstruction were improved significantly in the treatment group, according to both objective and subjective evaluation. There was no objective evidence of a reduction in outflow resistance or obstruction in either group.
J W
JW
Ramsay
G I
GI
Scott
H N
HN
Whitfield
D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D006801:Humans; D008297:Male; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000150:complications*; D011799:Quinazolines / Q000009:adverse effects / Q000627:therapeutic use*; D001748:Urinary Bladder Neck Obstruction / Q000188:drug therapy* / Q000209:etiology; D014563:Urodynamics / Q000187:drug effects
D011799:Quinazolines; C047638:alfuzosin