Peptide coincidence in rat superior cervical ganglion.
The immunofluorescent localization of substance P (SP), somatostatin and methionine enkephalin has been determined in the rat superior cervical ganglion of the sympathetic nervous system. Immunoreactivity was confined to the norepinephrine-containing post-ganglionic neurons and their processes. Nearly 20% of the postganglionic somata demonstrate dual coincidence in staining for SP-somatostatin, somatostatin-enkephalin, or SP-enkephalin. Almost 10% of the positively stained neurons show a coincident staining of all 3 peptide compounds within their somata. This suggests that multiple neurotransmitter chemicals may be employed by the postganglionic cells of the superior cervical ganglion.
Ariano
M A
MA
Kenny
S L
SL
D000818:Animals; D002452:Cell Count; D004744:Enkephalin, Methionine / Q000032:analysis; D005455:Fluorescent Antibody Technique; D005728:Ganglia, Sympathetic / Q000032:analysis*; D009419:Nerve Tissue Proteins / Q000032:analysis*; D009474:Neurons / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains; D013004:Somatostatin / Q000032:analysis; D013373:Substance P / Q000032:analysis
D009419:Nerve Tissue Proteins; D013373:Substance P; D013004:Somatostatin; D004744:Enkephalin, Methionine