Latex agglutination: an appropriate technology for the diagnosis of bacterial meningitis in developing countries.
We evaluated prospectively the utility of a latex agglutination technique for the diagnosis of Haemophilus influenzae type b meningitis in a paediatric ward in India. Eight of 44 children had H. influenzae grown from cerebrospinal fluid. These proven cases plus four additional cases of H. influenzae meningitis were detected by the latex agglutination test. There were no cross reactions with other organisms. The high degree of sensitivity and specificity, combined with the speed and simplicity of this technique make it an appropriate method for developing countries.
Venkatesh
V C
VC
Steinhoff
M C
MC
Moses
P
P
Jadhav
M
M
Pereira
S M
SM
D002648:Child; D002675:Child, Preschool; D003906:Developing Countries; D006193:Haemophilus influenzae / Q000302:isolation & purification; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007841:Latex Fixation Tests; D008583:Meningitis, Haemophilus / Q000175:diagnosis* / Q000209:etiology / Q000382:microbiology; D011446:Prospective Studies