Nucleotide sequence of the visna lentivirus: relationship to the AIDS virus.
We have determined the complete 9202 nucleotide sequence of the visna lentivirus. The deduced genetic organization most closely resembles that of the AIDS retrovirus in that there is a novel central region separating pol and env. Moreover, there is a close phylogenetic relationship between the conserved reverse transcriptase and endonuclease/integrase domains of the visna and AIDS viruses. These findings support the inclusion of the AIDS virus in the retroviral subfamily Lentivirinae.
P
P
Sonigo
M
M
Alizon
K
K
Staskus
D
D
Klatzmann
S
S
Cole
O
O
Danos
E
E
Retzel
P
P
Tiollais
A
A
Haase
S
S
Wain-Hobson
D000163:Acquired Immunodeficiency Syndrome / Q000382:microbiology; D000595:Amino Acid Sequence; D001483:Base Sequence; D003001:Cloning, Molecular; D003062:Codon; D004247:DNA; D004279:DNA, Viral; D017977:Deltaretrovirus / Q000145:classification / Q000235:genetics*; D004720:Endonucleases / Q000235:genetics; D015683:Gene Products, gag; D005814:Genes, Viral; D010802:Phylogeny; D012194:RNA-Directed DNA Polymerase / Q000235:genetics; D012091:Repetitive Sequences, Nucleic Acid; D014759:Viral Envelope Proteins / Q000235:genetics; D014764:Viral Proteins / Q000235:genetics; D014790:Visna-maedi virus / Q000145:classification / Q000235:genetics*
D003062:Codon; D004279:DNA, Viral; D015683:Gene Products, gag; D014759:Viral Envelope Proteins; D014764:Viral Proteins; D004247:DNA; D012194:RNA-Directed DNA Polymerase; D004720:Endonucleases