Therapeutic trials using tacrine and other cholinesterase inhibitors.
At this time, the data available on tacrine are inconclusive with respect to efficacy. Preliminary data are often overinterpreted, and it seems prudent to wait for the results of the ongoing multicenter double-blind studies before reaching a definite conclusion about efficacy.
Gamzu
E R
ER
Parke-Davis Pharmaceutical Research Division, University of California, San Diego.
Thal
L J
LJ
Davis
K L
KL
D000544:Alzheimer Disease / Q000188:drug therapy* / Q000378:metabolism; D000609:Aminoacridines / Q000627:therapeutic use*; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D006801:Humans; D013619:Tacrine / Q000627:therapeutic use*
D000609:Aminoacridines; D002800:Cholinesterase Inhibitors; D013619:Tacrine