[Clinical and pathogenetic aspects of aspirin intolerance].
Aspirin intolerance has become increasingly important in clinical dermatology during the past decade, especially as a diagnostic aid in chronic urticaria. It is recommended, to distinguish clinically between the intolerance syndrome and an intolerance provocation (of preexistent asthma or urticaria). Pathogenetically, various antibody-independent mechanisms are discussed of which most authors favour a defective regulation of arachidonic acid metabolism.
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Voigtländer
D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000378:metabolism; D001241:Aspirin / Q000009:adverse effects*; D001249:Asthma / Q000139:chemically induced; D003167:Complement Activation / Q000187:drug effects; D003875:Drug Eruptions / Q000209:etiology*; D006636:Histamine Release / Q000187:drug effects; D006801:Humans; D011448:Prostaglandin Antagonists
D001095:Arachidonic Acids; D011448:Prostaglandin Antagonists; D016718:Arachidonic Acid; D001241:Aspirin
Klinische und pathogenetische Aspekte der Aspirin-Intoleranz.