[Small intestinal perforation as complication of loperamide treatment of Salmonella typhimurium infection].
A patient is described with an acute gastroenteritis, after ingestion of French fries and a raw egg and the simultaneous use of loperamide, due to an infection with Salmonella typhimurium phage type 10. As a complication multiple perforations of the ileum developed which needed surgical resection. This is the first report of this complication in the literature. The simultaneous use of loperamide is suspected to be the promoting factor in the development of this complication.
Afd. Interne Geneeskunde, Academisch Ziekenhuis, Maastricht.
R J
RJ
Loffeld
P B
PB
Soeters
D000293:Adolescent; D005260:Female; D006801:Humans; D007077:Ileal Diseases / Q000139:chemically induced / Q000209:etiology*; D007416:Intestinal Perforation / Q000139:chemically induced / Q000209:etiology*; D008139:Loperamide / Q000009:adverse effects* / Q000627:therapeutic use; D010880:Piperidines / Q000009:adverse effects*; D012478:Salmonella Food Poisoning / Q000150:complications* / Q000188:drug therapy
D010880:Piperidines; D008139:Loperamide
Dunne-darmperforatie als complicatie van een behandeling met loperamide bij een infectie met Salmonella typhimurium.