Dendritic cells of the chicken spleen are capable in vivo of giant cell formation.
In this report, we offer evidence that carrageenan, a polyclonal B-cell mitogen, and Salmonella O antigen, when administered together, can induce in vivo multinucleated giant cells from dendritic cells in the chicken spleen.
Olah
I
I
Glick
B
B
D000818:Animals; D000942:Antigens, Bacterial / Q000008:administration & dosage; D002351:Carrageenan / Q000494:pharmacology*; D002645:Chickens; D008854:Microscopy, Electron; D019081:O Antigens; D013154:Spleen / Q000166:cytology* / Q000187:drug effects / Q000648:ultrastructure
D000942:Antigens, Bacterial; D019081:O Antigens; D002351:Carrageenan