[Expression of antigens related to structural protein antigens of MMTV in breast cancer cells].
This study was concerned with expression of MMTV-related antigens in cells of stable MCF-7 and T47D lines of human breast cancer. Indirect immunoperoxidase technique using antisera against whole preparations of virus of RIII and C3H mice as well as certain MMTV proteins identified cells which express proteins cross-reactive with both gp52 and p27. MCF-7 sublines with a high level of positive cells were obtained. The stimulating effect of pregnancy and lactation hormones on MMTV-related proteins was studied.
Litvinov
S V
SV
Golovkina
T V
TV
D000951:Antigens, Neoplasm / Q000032:analysis*; D000956:Antigens, Viral / Q000032:analysis*; D001374:Azacitidine / Q000494:pharmacology; D001943:Breast Neoplasms / Q000276:immunology*; D002460:Cell Line; D002999:Clone Cells / Q000187:drug effects / Q000276:immunology; D003907:Dexamethasone / Q000494:pharmacology; D004958:Estradiol / Q000494:pharmacology; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008324:Mammary Tumor Virus, Mouse / Q000276:immunology*; D011374:Progesterone / Q000494:pharmacology; D014764:Viral Proteins / Q000276:immunology*
D000951:Antigens, Neoplasm; D000956:Antigens, Viral; D014764:Viral Proteins; D011374:Progesterone; D004958:Estradiol; D003907:Dexamethasone; D001374:Azacitidine
Ekspressiia v kletkakh raka molochnoĭ zhelezy antigenov, rodstvennykh antigenam strukturnykh belkov MMTV.