Effect of ibuprofen on the postburn hypermetabolic response: a case report.
Severely burned patients exhibit a postburn hypermetabolic response which, with the most severe burns, can double the patient's metabolic rate. We report on a 54-year-old man who was on long-term ibuprofen administration for treatment of arthritis before sustaining a 38% total body surface area burn. This patient failed to demonstrate the normal hypermetabolic response. The possibility that the ibuprofen administration prevented the hypermetabolic response is discussed.
Shriners Burns Institute, Cincinnati, Ohio.
J P
JP
Waymack
M
M
Jenkins
M
M
Gottschlich
J W
JW
Alexander
G D
GD
Warden
D001168:Arthritis / Q000188:drug therapy; D001481:Basal Metabolism / Q000187:drug effects; D002056:Burns / Q000378:metabolism*; D002153:Calorimetry, Indirect; D004734:Energy Metabolism / Q000187:drug effects*; D006801:Humans; D007052:Ibuprofen / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D007052:Ibuprofen