Anaerobes: problems and controversies in bacteriology, infections, and susceptibility testing.
Three key questions are discussed in this manuscript: (1) What is the clinical relevance of anaerobic bacteriology? (2) How can the microbiologist, with limited and decreasing resources, perform reliable, detailed studies of anaerobic bacteriology? (3) When and how should susceptibility testing be done with anaerobes? If the clinician knows the usual bacteriology of various types of infection and how this may be modified by pathophysiologic processes in the host or by prior therapy, he/she can use a logical empiric approach to treatment of the patient. As to the microbiologist's dilemma, it is not realistic or rational for a microbiologist in a nonteaching hospital to do detailed bacteriologic studies and routine anaerobic susceptibility testing. The resources available should be committed primarily to the patient who is seriously ill. Such allocation of resources, of course, requires repeated and effective communication between microbiologist and clinician.
Medical Service, Wadsworth Veterans Administration Medical Center, Los Angeles, California 90073.
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Finegold
D001421:Bacteria, Anaerobic / Q000187:drug effects / Q000502:physiology*; D001424:Bacterial Infections / Q000382:microbiology*; D001431:Bacteriological Techniques; D006801:Humans; D008826:Microbial Sensitivity Tests