Effect of ibuprofen on the postburn hypermetabolic response: a case report.
Severely burned patients exhibit a postburn hypermetabolic response which, with the most severe burns, can double the patient's metabolic rate. We report on a 54-year-old man who was on long-term ibuprofen administration for treatment of arthritis before sustaining a 38% total body surface area burn. This patient failed to demonstrate the normal hypermetabolic response. The possibility that the ibuprofen administration prevented the hypermetabolic response is discussed.
Waymack
J P
JP
Shriners Burns Institute, Cincinnati, Ohio.
Jenkins
M
M
Gottschlich
M
M
Alexander
J W
JW
Warden
G D
GD
D001168:Arthritis / Q000188:drug therapy; D001481:Basal Metabolism / Q000187:drug effects; D002056:Burns / Q000378:metabolism*; D002153:Calorimetry, Indirect; D004734:Energy Metabolism / Q000187:drug effects*; D006801:Humans; D007052:Ibuprofen / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D007052:Ibuprofen