[Histology and immunopathology of colonic carcinoma].
The correlation among lymphoid cell infiltration (LI), cell-mediated immunity and immunoglobulin-containing cells distribution in the colon cancer was studied in resected materials of 136 patients with colonic cancer. The results were as follows: 1) LI of the colon cancer tended to be found more commonly in patients with colonic cancer in clinical early stage than advanced stage. 2) The cumulative 5-year survival rate in patients with positive LI was longer than that in the patients with negative or normal LI. 3) In colonic cancer patients with the better prognosis, IgA-containing cells were distributed around the tumor tissues more abundantly than that in the poor ones. 4) These results suggest that the IgA system somewhat participates in cancer immunity.
Usami
S
S
Department of Surgery, Kariya Toyota General Hospital, Kanjya, Japan.
Sato
M
M
Matsumoto
K
K
Nishiwaki
K
K
Ohkubo
T
T
Kotani
H
H
Yura
J
J
D003110:Colonic Neoplasms / Q000276:immunology / Q000401:mortality / Q000473:pathology*; D006801:Humans; D007111:Immunity, Cellular; D007070:Immunoglobulin A / Q000032:analysis; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000276:immunology; D011379:Prognosis
D007070:Immunoglobulin A