[Effect of Biseptol on the state of gastric mucosa in the white rat under experimental conditions (after excision of one lobe of the liver or one kidney)].
The effect of Biseptol on the mucous membrane of the stomach of an unoperated white rat was analysed and also the effect after liver lobectomy or unilateral nephrectomy. There were performed histochemical reactions to mucopolysaccharides and nucleic acids as well as staining with hematoxyline ond eosine. After administration of Biseptol in a dose of 270 mg/kg b.w. for 7 consecutive d, increased secretion of mucous and inflammation in gastric mucous membrane was observed. No intensification of these symptoms was found after administration of Biseptol to operated animals. It may be supposed that hepatectomy and nephrectomy are not counterindications for the use of Biseptol.
Czerny
K
K
Ciszewska-Popiołek
B
B
Dowgird
E
E
D000818:Animals; D000892:Anti-Infective Agents, Urinary / Q000494:pharmacology*; D004338:Drug Combinations / Q000494:pharmacology; D005753:Gastric Mucosa / Q000187:drug effects* / Q000378:metabolism; D006025:Glycosaminoglycans / Q000378:metabolism; D006498:Hepatectomy; D006651:Histocytochemistry; D007668:Kidney / Q000502:physiology*; D008099:Liver / Q000502:physiology*; D008297:Male; D009392:Nephrectomy; D051381:Rats; D013194:Staining and Labeling; D013420:Sulfamethoxazole / Q000494:pharmacology*; D014295:Trimethoprim / Q000494:pharmacology*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
D000892:Anti-Infective Agents, Urinary; D004338:Drug Combinations; D006025:Glycosaminoglycans; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim; D013420:Sulfamethoxazole
Untersuchungen des Einflusses von Biseptol auf den Zustand der Magenschleimhaut der weissen Ratte unter Versuchsbedingungen (nach der Entfernung eines Leberlappens oder einer Niere).