Human aggression and the role of central serotonin.
Human intraspecies aggression can be defined as a broad sequential pattern of psychic experience and/or behavior, the goal response to which is to deliver stimuli suitable to damage the integrity of a social partner, the subject itself, or a surrogate-object. This article reviews work concerning human aggression, auto-aggression (suicide) and the role of central serotonin. The impact of a "high-risk - low 5-HIAA group" upon clinical psychiatric practice is discussed. Damaging and self-destructive experience and behavior and its biochemical aspects are regarded as a dysbalance syndrome causing well-defined vulnerability, which, in turn, becomes the basis of the psychopathology and psychodynamics of phenomena like aggression.
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Mühlbauer
D000374:Aggression / Q000502:physiology*; D001921:Brain / Q000503:physiopathology*; D003866:Depressive Disorder / Q000503:physiopathology; D006719:Homovanillic Acid / Q000134:cerebrospinal fluid; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000134:cerebrospinal fluid; D007398:Interpersonal Relations; D008734:Methoxyhydroxyphenylglycol / Q000134:cerebrospinal fluid; D009638:Norepinephrine / Q000502:physiology; D011985:Receptors, Serotonin / Q000502:physiology*; D012306:Risk; D012701:Serotonin / Q000502:physiology*; D013405:Suicide / Q000523:psychology; D014754:Violence
D011985:Receptors, Serotonin; D012701:Serotonin; D008734:Methoxyhydroxyphenylglycol; D006897:Hydroxyindoleacetic Acid; D009638:Norepinephrine; D006719:Homovanillic Acid