[Leukergy-stimulating factors in polycythemia vera].
In a group of patients with polycythaemia vera (n = 10) a leukocyte activation could be identified in all cases by leukocyte agglomeration (LA). During full remission, LA remained within the normal range in nearly all patients. By means of plasma exchange trials leukocyte activation could be demonstrated to be caused by humoral factors being insensitive to inactivation at 56 degrees C. Factors stimulating leukergy apparently indicate a close relation to the activity of myelopoiesis. Its evidence can be applied as a diagnostic criterion for polycythaemia vera.
Fischer
H
H
D000328:Adult; D002066:Busulfan / Q000627:therapeutic use; D002449:Cell Aggregation; D005260:Female; D006801:Humans; D007962:Leukocytes / Q000502:physiology*; D008213:Lymphocyte Activation; D008222:Lymphokines / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011087:Polycythemia Vera / Q000188:drug therapy / Q000503:physiopathology*
D008222:Lymphokines; D002066:Busulfan
Leukergie stimulierende Faktoren bei Polyzythaemia vera.