The effect of neonatal anoxia on brain cholecystokinin-8-like immunoreactivity and monoamine levels of mature rats.
The effect of neonatal anoxia upon cholecystokinin-8-like immunoreactivity (CCK-8-I) concentrations was investigated in different brain areas of mature rats. Anoxia within 24 h after birth resulted in significantly lower CCK-8-I levels in the cortex, nucleus accumbens, amygdala and hypothalamus of 10-week-old rats. In contrast, no change was observed in the monoamine levels of these brain areas. The data suggest that neonatal anoxia selectively affects CCK-containing neurons.
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Yamamoto
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Kato
D000818:Animals; D000831:Animals, Newborn; D001679:Biogenic Amines / Q000032:analysis*; D001923:Brain Chemistry; D005260:Female; D006719:Homovanillic Acid / Q000032:analysis; D006897:Hydroxyindoleacetic Acid / Q000032:analysis; D002534:Hypoxia, Brain / Q000378:metabolism*; D008297:Male; D009638:Norepinephrine / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000032:analysis; D012844:Sincalide / Q000032:analysis*
D001679:Biogenic Amines; D012701:Serotonin; D006897:Hydroxyindoleacetic Acid; D012844:Sincalide; D009638:Norepinephrine; D006719:Homovanillic Acid