Use of a modified test system to determine early pregnancy factor (EPF) levels in patients with normal first trimester pregnancy and after therapeutic abortion.
Human pregnancy can be recognized as early as 48 hours after conception using the rosette inhibition test (RIT) to detect early pregnancy factor (EPF). A modification of the test as originally described by Morton et al. is demonstrated using a monoclonal pan T-cell antibody. Studies were performed to investigate the relationship between EPF levels during normal first trimester intact pregnancies and therapeutic abortions. The change in EPF levels is compared with those of hormones after interrupted pregnancy.
Tinneberg
H R
HR
Staves
R P
RP
Hanf
V
V
Scholz
W
W
Semm
K
K
Mettler
L
L
D000032:Abortion, Therapeutic; D018835:Chaperonin 10; D006063:Chorionic Gonadotropin / Q000097:blood; D018997:Chorionic Gonadotropin, beta Subunit, Human; D004958:Estradiol / Q000097:blood; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000032:analysis*; D010446:Peptide Fragments / Q000097:blood; D010455:Peptides; D011247:Pregnancy; D011257:Pregnancy Proteins; D011261:Pregnancy Trimester, First; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood; D012016:Reference Values; D012397:Rosette Formation; D013491:Suppressor Factors, Immunologic; D013997:Time Factors
D018835:Chaperonin 10; D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D007166:Immunosuppressive Agents; D010446:Peptide Fragments; D010455:Peptides; D011257:Pregnancy Proteins; D013491:Suppressor Factors, Immunologic; C025124:early pregnancy factor; D011374:Progesterone; D004958:Estradiol; D011388:Prolactin