Immunologic factors related to survival and performance in neonatal swine.
Logistic regression was used to develop models predicting preweaning survival in 334 neonatal swine. Measured risk factors included birth weight, litter size (live born), dam parity, serum IgG concentration, serum ELISA titers recognizing common gram-negative core antigens, and serum concentrations of the third component of complement. Larger birth weights were associated with increased probability of preweaning survival. The highest mortality was observed in litters with more than 12 pigs. Pigs with serum concentration of the third component of complement (C3) in the lowest stratum, less than 20% adult pooled C3 standard (APC3), had reduced mortality, compared with high (greater than 38% APC3) and middle (20 to 38% APC3) groups. Associations between all other variables, including total serum IgG concentration and preweaning survival were not significant. Few pigs had hypogammaglobulinemia, less than 3% of the study population had serum IgG concentrations less than 1 g/dl. Of all measured variables, only birth weight and dam parity were significant predictors of preweaning gain. Larger pigs and pigs born to third or greater parity dams had more preweaning gain than other pigs.
Tyler
J W
JW
Department of Clinical Pathology, School of Veterinary Medicine, University of California, Davis 95616.
Cullor
J S
JS
Thurmond
M C
MC
Douglas
V L
VL
Parker
K M
KM
D000818:Animals; D000831:Animals, Newborn / Q000097:blood / Q000276:immunology*; D001724:Birth Weight; D003176:Complement C3 / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005260:Female; D007074:Immunoglobulin G / Q000032:analysis; D008098:Litter Size; D009026:Mortality; D010298:Parity; D012307:Risk Factors; D015996:Survival Rate; D013552:Swine / Q000097:blood / Q000276:immunology*
D003176:Complement C3; D007074:Immunoglobulin G