[The role of a protein factor in the effect of alpha-tocopherol on mitochondrial respiration].
It is shown that alpha-tocopherol in vitro stimulates respiration of the liver mitochondria in E-hypovitaminosis rats only in the presence of the specific protein factor isolated from the liver cytosol. The action of alpha-tocopherol on mitochondria in the presence of NAD and a protein factor is not accompanied by an increase in the NADH level, that evidences for the absence of the direct redox interaction between NAD and tocopherol.
Donchenko
G V
GV
Malen'kykh
L B
LB
Palyvoda
O M
OM
Zhalylo
L I
LI
D000818:Animals; D005260:Female; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D009243:NAD / Q000378:metabolism; D010084:Oxidation-Reduction; D010101:Oxygen Consumption / Q000187:drug effects*; D011506:Proteins / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D014810:Vitamin E / Q000494:pharmacology*; D014811:Vitamin E Deficiency / Q000378:metabolism*
D011506:Proteins; D009243:NAD; D014810:Vitamin E
Rol' bilkovogo chynnyka v diï alpha-tokoferolu na dykhannia mitokhondriĭ.