[Evaluation of diagnostic potential of various methods of chorionic sampling in the first trimester of pregnancy].
Potentials of the most common chorionic sampling methods have been examined: transcervical biopsy (TCB) (n-65), transcervical aspiration (TCA) (n-63) and transabdominal aspiration (TAA) (n-10). These procedures were done in outpatient settings at 6-12 week's gestation with sonographic guidance using accepted methodologies. TCB and TCA yielded 14.3 mg and 27.5 mg of a sample, respectively. The chorionic sample obtained with TAA was at best 3 mg. The incidence of successful chorionic sampling was 92.4% for TCB, 76.1% for TCA and 80.0% for TAA. Spontaneous abortions occurred after TAA (7.9%) and combined transcervical procedures (10%). These results suggest a potential of TCB and TCA in first-trimester prenatal diagnosis, but TCB has a number of advantages. TAA is a promising technique which, however, requires further sophistication.
Bakharev
V A
VA
Karetnikova
N A
NA
Iantovskiĭ
Iu R
IuR
D000328:Adult; D000553:Ambulatory Care; D001707:Biopsy, Needle / Q000379:methods; D002823:Chorion / Q000473:pathology*; D015193:Chorionic Villi Sampling / Q000295:instrumentation / Q000379:methods*; D005260:Female; D030342:Genetic Diseases, Inborn / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy; D011261:Pregnancy Trimester, First
Otsenka vozmozhnosteĭ razlichnykh sposobov polucheniia tkani khoriona v I trimestre beremennosti.