Intrinsic release rate from matrix-type drug delivery systems.
A simple method was presented for evaluation of the intrinsic release rate from a matrix-type drug delivery system. The effect of the hydrodynamic diffusion boundary layer on the rate of drug release was corrected to obtain the release profile without any diffusion boundary layer effect. The experimental release data was logically explained in terms of the intrinsic rate of release evaluated from the present method.
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D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002715:Chlormadinone Acetate; D003692:Delayed-Action Preparations; D004058:Diffusion; D007700:Kinetics; D008962:Models, Theoretical; D012826:Silicone Elastomers; D012995:Solubility
D003692:Delayed-Action Preparations; D012826:Silicone Elastomers; D002715:Chlormadinone Acetate