[Clinical investigation of basic fetoprotein (BFP) and carcinoembryonic antigen (CEA) in stomach cancer and lung cancer].
The object of present study is to investigate the clinical value of BFP and CEA in stomach and lung cancer. BFP-positive cases were found in 36.8% of 378 stomach cancer and in 65.2% of 89 lung cancer. CEA-positive cases revealed in 37.6% of 205 stomach cancer and in 65.6% of 64 lung cancer. In serum levels of BFP, there was no difference between differentiated type and undifferentiated type of stomach cancer by histological classification. In lung cancer, BFP levels in serum of large cell type were significantly higher than those of other types. The combination assay using BFP and CEA revealed 54.1% and 82.8% positive rate of stomach cancer and lung cancer, respectively. These results suggested that BFP and CEA assay appeared to be available for elevation of cancer diagnosis, especially useful for diagnosis of lung cancer.
Kanda
Y
Y
Ishii
M
M
D000230:Adenocarcinoma / Q000276:immunology; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D002277:Carcinoma / Q000276:immunology; D018288:Carcinoma, Small Cell / Q000276:immunology; D002294:Carcinoma, Squamous Cell / Q000276:immunology; D006801:Humans; D008175:Lung Neoplasms / Q000276:immunology*; D011014:Pneumonia / Q000276:immunology; D013274:Stomach Neoplasms / Q000276:immunology*; D013276:Stomach Ulcer / Q000276:immunology; D014397:Tuberculosis, Pulmonary / Q000276:immunology; D000509:alpha-Fetoproteins / Q000032:analysis*
D002272:Carcinoembryonic Antigen; D000509:alpha-Fetoproteins