Imaging of water distribution in the rat brain by activation autoradiography.
Regional water distribution in the rat brain was obtained autoradiographically by activation analysis. The autoradiogram obtained for the normal rat brain showed high accumulation of water in the areas of sensory-motor cortex, hippocampus, thalamus, and amygdaloid cortex, whereas corpus callosum and internal capsule showed low water contents as expected. The estimated values of water content were 78.6 +/- 4.9 weight % for gray matter, and 73.5 +/- 4.9 weight % for white matter, respectively. The mean values of the water content were consistent with those obtained by a conventional drying-weighing method.
Department of Neurology, Tohoku University School of Medicine, Sendai, Japan.
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Kogure
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Kawashima
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Iwata
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Ido
D000818:Animals; D001345:Autoradiography / Q000379:methods*; D001834:Body Water / Q000032:analysis* / Q000528:radiation effects; D001921:Brain / Q000473:pathology / Q000528:radiation effects; D001923:Brain Chemistry; D001929:Brain Edema / Q000378:metabolism*; D005462:Fluorine Radioisotopes / Q000032:analysis; D008297:Male; D009686:Nuclear Physics; D009929:Organ Size; D010100:Oxygen / Q000528:radiation effects; D051381:Rats; D011919:Rats, Inbred Strains
D005462:Fluorine Radioisotopes; D010100:Oxygen