Idiopathic fibrosing alveolitis: a review with emphasis on ultrastructural and immunohistochemical features.
Fibrosing alveolitis is a usually chronic pulmonary disease affecting middle-aged men and women and causing progressive dyspnea. This review discusses the nosologic, etiologic, immunopathogenic, histologic, immunohistochemical and ultrastructural features of this condition. A hypothesis is presented suggesting microvascular damage as the primary pathologic change in cases associated with collagen vascular diseases and viral pneumonia.
S P
SP
Hammar
R H
RH
Winterbauer
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D
Bockus
F
F
Remington
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S
Friedman
D000163:Acquired Immunodeficiency Syndrome / Q000473:pathology; D001706:Biopsy; D005260:Female; D005353:Fibronectins / Q000032:analysis; D006133:Growth Substances / Q000032:analysis; D006651:Histocytochemistry; D006801:Humans; D007370:Interferon Type I / Q000032:analysis; D007633:Keratins / Q000032:analysis; D008168:Lung / Q000473:pathology; D008297:Male; D008833:Microcirculation; D008854:Microscopy, Electron; D008970:Molecular Weight; D010994:Pleura / Q000473:pathology; D011658:Pulmonary Fibrosis / Q000473:pathology*; D013601:T-Lymphocytes / Q000032:analysis
D005353:Fibronectins; D006133:Growth Substances; D007370:Interferon Type I; D007633:Keratins