Malignant melanoma at sites of therapeutic X-irradiation.
Two patients are reported in whom malignant melanoma developed at sites of low-dose superficial X-ray therapy given for treatment of benign dermatoses. No causal link has been established between melanoma and X-irradiation, but previous reports of a possible association are reviewed. The probably importance of ultraviolet exposure after X-irradiation in such patients is emphasised.
Rupert Hallam Department of Dermatology, Royal Hallamshire Hospital, Sheffield, UK.
A J
AJ
McDonagh
A L
AL
Wright
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000209:etiology* / Q000601:surgery; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects*; D012878:Skin Neoplasms / Q000209:etiology* / Q000601:surgery; D014964:X-Ray Therapy / Q000009:adverse effects*