Immunoglobulin allotypes in myasthenia gravis patients with a thymoma.
Gm and Km allotypes were examined in 29 myasthenia gravis patients with a thymoma and non-receptor skeletal muscle antibodies. The frequency of the phenotype Gm1,2,3;23;5,21 was significantly higher in the patients than in 292 healthy controls (P less than 0.01). Km allotype frequencies did not differ in patients and controls.
Gilhus
N E
NE
Department of Neurology, University of Bergen, Norway.
Pandey
J P
JP
Gaarder
P I
PI
Aarli
J A
JA
D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001323:Autoantibodies / Q000097:blood / Q000276:immunology; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000276:immunology*; D005260:Female; D006386:Hemagglutination Tests; D006801:Humans; D007126:Immunoglobulin Allotypes / Q000276:immunology*; D007074:Immunoglobulin G / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000276:immunology; D009157:Myasthenia Gravis / Q000150:complications / Q000276:immunology*; D010641:Phenotype; D011950:Receptors, Cholinergic / Q000276:immunology; D013945:Thymoma / Q000150:complications / Q000276:immunology*; D013953:Thymus Neoplasms / Q000150:complications / Q000276:immunology*
D001323:Autoantibodies; D007126:Immunoglobulin Allotypes; D007074:Immunoglobulin G; D011950:Receptors, Cholinergic