Inhalant allergy following occupational exposure to blowflies.
An allergic reaction, provoked by exposure to the blowfly Lucilia cuprina and shown to be IgE-mediated, occurred in a subject employed in an entomological research laboratory. The subject's serum, and sera from three other asthmatic patients with IgE antibodies to blowfly extracts, also reacted with extracts from the screw-worm fly (Chrysomya bezziana). Results suggested that antigens from the two species share immunological cross-reactivity. Cross-reactions also exist between the different developmental stages of both species. Allergic reactions to inhaled insect allergens may not be uncommon in the Australian community.
G L
GL
Kaufman
B A
BA
Baldo
E R
ER
Tovey
T E
TE
Bellas
B H
BH
Gandevia
D000328:Adult; D000395:Air Pollutants, Occupational / Q000032:analysis / Q000302:isolation & purification; D000485:Allergens / Q000032:analysis; D001249:Asthma / Q000276:immunology; D001315:Australia; D003429:Cross Reactions; D004175:Diptera / Q000276:immunology*; D000939:Epitopes / Q000032:analysis; D005541:Forced Expiratory Volume; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D008297:Male; D009784:Occupational Diseases / Q000276:immunology*; D011852:Radioallergosorbent Test / Q000379:methods; D012130:Respiratory Hypersensitivity / Q000276:immunology*; D012221:Rhinitis, Allergic, Perennial / Q000276:immunology; D012882:Skin Tests
D000395:Air Pollutants, Occupational; D000485:Allergens; D000939:Epitopes; D007073:Immunoglobulin E