[239Pu metabolism after its intratracheal administration].
The paper is concerned with the results of distribution and kinetics of metabolism of 239Pu-citrate in the respiratory tracts. Time-periods of the accumulation and excretion of this radionuclide from various tissue systems were defined. Data on the time course of 239Pu resorption from the lungs to organs and tissues, first of all to the blood, especially at the early stage of metabolism (up to 1-3 days), are the basis for the optimization of a method of osseous tissue protection against the radionuclide by using competitive action of iron preparations.
N S
NS
Shvydko
N P
NP
Ivanova
S I
SI
Rushonik
D000818:Animals; D002951:Citrates / Q000008:administration & dosage / Q000493:pharmacokinetics*; D006207:Half-Life; D008297:Male; D009942:Organometallic Compounds / Q000008:administration & dosage / Q000493:pharmacokinetics*; D011005:Plutonium / Q000008:administration & dosage / Q000493:pharmacokinetics*; D051381:Rats; D012996:Solutions; D013997:Time Factors; D014018:Tissue Distribution / Q000502:physiology / Q000528:radiation effects; D014132:Trachea
D002951:Citrates; D009942:Organometallic Compounds; D012996:Solutions; D011005:Plutonium
Obmen 239Pu posle intratrakheal'nogo vvedeniia.