2-substituted-N5-(2'-aminophenyl)-4-thiohydantoic acids as aminopeptidase inhibitors with pro-antinociceptive activity.
Welsh School of Pharmacy, UWCC, Cardiff, U.K.
Z
Z
Yu
P S
PS
Williams
A
A
Patel
H J
HJ
Smith
R D
RD
Sewell
J P
JP
Gonzalez
D000626:Aminopeptidases / Q000037:antagonists & inhibitors*; D000700:Analgesics; D000818:Animals; D004347:Drug Interactions; D004743:Enkephalin, Leucine / Q000031:analogs & derivatives / Q000494:pharmacology; D016308:Enkephalin, Leucine-2-Alanine; D006827:Hydantoins / Q000494:pharmacology*; D066298:In Vitro Techniques; D051379:Mice; D009270:Naloxone / Q000494:pharmacology; D010147:Pain Measurement; D011691:Puromycin / Q000494:pharmacology; D013867:Thiohydantoins / Q000494:pharmacology*
D000700:Analgesics; D006827:Hydantoins; D013867:Thiohydantoins; D009270:Naloxone; D011691:Puromycin; D004743:Enkephalin, Leucine; D016308:Enkephalin, Leucine-2-Alanine; D000626:Aminopeptidases