Diffuse malignant pericardial mesothelioma.
A 67-year-old male case of pericardial mesothelioma is reported. The diagnosis was established by the gross appearance at autopsy and its histological findings. The tumor arising from the anterior epicardium of the right half of the heart was located within the pericardial sac, and displaced and compressed the heart to the posterior direction. Histologically, large areas of the tumor were composed of spindle-shaped malignant cells which were arranged in interlacing bundles. The other areas showed the presence of tubular structures and ill-defined solid nests. Distant metastasis was found only in a small focus of the 8th vertebral bone marrow composed of spindle-shaped cells. A meticulous search failed to find any tumor in other organs. Based on these findings, the tumor was diagnosed as diffuse malignant mesothelioma of biphasic type.
Nomori
H
H
Shimosato
Y
Y
Tsuchiya
R
R
D000199:Actins / Q000032:analysis; D000368:Aged; D000951:Antigens, Neoplasm / Q000032:analysis; D002272:Carcinoembryonic Antigen / Q000032:analysis; D006338:Heart Neoplasms / Q000473:pathology*; D006801:Humans; D007633:Keratins / Q000032:analysis; D008297:Male; D008654:Mesothelioma / Q000032:analysis / Q000175:diagnosis / Q000473:pathology*; D010496:Pericardium / Q000473:pathology*
D000199:Actins; D000951:Antigens, Neoplasm; D002272:Carcinoembryonic Antigen; D007633:Keratins