Comparative inhibitory effects of mefloquine and primaquine on hepatic drug-metabolizing enzymes.
Sukhumanan
T
T
Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand.
Suphakawanich
W
W
Thithapandha
A
A
D000429:Alcohol Oxidoreductases / Q000037:antagonists & inhibitors; D000633:Aminopyrine N-Demethylase / Q000037:antagonists & inhibitors; D000815:Aniline Hydroxylase / Q000037:antagonists & inhibitors; D000818:Animals; D004791:Enzyme Inhibitors; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D015767:Mefloquine / Q000494:pharmacology*; D010089:Oxidoreductases, N-Demethylating / Q000037:antagonists & inhibitors; D010090:Oxidoreductases, O-Demethylating / Q000037:antagonists & inhibitors; D011319:Primaquine / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
D004791:Enzyme Inhibitors; C026048:4-nitroanisole O-demethylase; D010090:Oxidoreductases, O-Demethylating; D000429:Alcohol Oxidoreductases; C021353:hexobarbital oxidase; D000815:Aniline Hydroxylase; C030154:4-chloro-N-methylaniline demethylase; D010089:Oxidoreductases, N-Demethylating; D000633:Aminopyrine N-Demethylase; D011319:Primaquine; D015767:Mefloquine