Disseminated porokeratosis in an infant with craniosynostosis.
An infant with craniosynostosis and other congenital defects developed a progressive skin rash from the age of 1 month. Histological examination revealed dyskeratosis and a cornoid lamella suggestive of porokeratosis. This patient is remarkable for the early onset and severity of the skin disease.
Hospitals for Sick Children, London, U.K.
M R
MR
Judge
M
M
Michaels
V R
VR
Sams
T J
TJ
David
J I
JI
Harper
D000015:Abnormalities, Multiple; D003398:Craniosynostoses / Q000150:complications*; D006801:Humans; D007223:Infant; D007642:Keratosis / Q000150:complications* / Q000473:pathology; D008297:Male; D012867:Skin / Q000473:pathology