[Onchocerciasis in travelers to the tropics].
Two men, aged 54 and 31 years respectively, developed an itching skin rash 18 and 6 months respectively after returning from a trip to Africa, the former also recurrent conjunctivitis. Two years and 6 months, respectively, passed from the time of first symptoms until the diagnosis of onchocerciasis was made. Both patients had an eosinophilia (10.5 and 19%) and specific antibodies against Onchocerca volvulus. Microfilaria were demonstrated in the skin of the younger man. The other one had bilateral corneal infiltrates. Both patients were treated with a single dose of ivermectin, 150 micrograms/kg. Within several months, the clinical symptoms and eosinophilia disappeared and the antibody titres decreased.
Junghanss
T
T
Schweizerisches Tropeninstitut, Basel.
Weiss
N
N
D000328:Adult; D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood; D004802:Eosinophilia / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology; D006801:Humans; D007559:Ivermectin / Q000627:therapeutic use; D008297:Male; D008842:Microfilariae / Q000302:isolation & purification; D008875:Middle Aged; D009854:Onchocerca / Q000276:immunology / Q000302:isolation & purification; D009855:Onchocerciasis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D015827:Onchocerciasis, Ocular / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology; D012867:Skin / Q000469:parasitology; D013997:Time Factors; D014195:Travel; D014329:Tropical Climate
D000909:Antibodies, Helminth; D007559:Ivermectin
Onchozerkose bei Tropenreisenden.