[Effect of immunostimulants on the intensity of vaccinal antirabies immunity].
Experiments in BALB/c and CBA mice demonstrated that among 5 immunopotentiators (RFf2, a complex of polyguacylic and polycytidylic acids (GC), glucosomuramyldipeptide, levamisole, and dsRNA) a significant immunostimulating effect on the intensity of rabies immunity to intracerebral challenge with street rabies virus was exerted by RFf2 interferon inductor or by a combination of inosiplex + + GC + vaccine. A correlation between the immunostimulating and protective (therapeutic) activity of the drugs was established.
Barinskiĭ
I F
IF
Gribencha
S V
SV
Ignat'ev
G M
GM
Amitina
N N
NN
Tazulakhova
E B
EB
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D007109:Immunity / Q000187:drug effects; D007369:Interferon Inducers / Q000494:pharmacology; D007372:Interferons / Q000097:blood; D051379:Mice; D008807:Mice, Inbred BALB C; D008808:Mice, Inbred CBA; D011818:Rabies / Q000276:immunology*; D011819:Rabies Vaccines / Q000276:immunology*
D000276:Adjuvants, Immunologic; D007369:Interferon Inducers; D011819:Rabies Vaccines; D007372:Interferons
Vliianie nekotorykh immunostimuliatorov na napriazhennost' vaktsinal'nogo antirabicheskogo immuniteta.