Oxidation of dopa in human albinism.
The urine of an albino woman contained small quantities of 5-S-cysteinyldopa; 6-hydroxy-5-methoxyindole-2-carboxylic acid, a melanin precursor metabolite, was lacking. The 5-S-cysteinyldopa excretion observed may reflect non-specific oxidation of dopa. Two other albino patients showed normal values for the excretion of 5-S-cysteinyldopa and of 6-hydroxy-5-methoxyindole-2-carboxylic acid.
R
R
Carstam
C
C
Hansson
G
G
Krook
H
H
Rorsman
E
E
Rosengren
L E
LE
Wirestrand
D000328:Adult; D000417:Albinism / Q000378:metabolism* / Q000652:urine; D003548:Cysteinyldopa / Q000652:urine; D004295:Dihydroxyphenylalanine / Q000378:metabolism*; D005260:Female; D006801:Humans; D007211:Indoles / Q000652:urine; D009994:Osmolar Concentration; D010084:Oxidation-Reduction
D007211:Indoles; D003548:Cysteinyldopa; C017408:6-hydroxy-5-methoxy-2-indolylcarboxylic acid; D004295:Dihydroxyphenylalanine