[Pyoderma gangrenosum and paraneoplastic chronic polyarthritis disclosing Hodgkin's lymphoma].
Pyoderma gangrenosum is a rare skin disease of unknown pathogenesis associated, in almost 8 out of 10 cases, with a systemic disease, notably enterocolitis or hemopathy. We report the case of a 57-year old man who had been presenting with pyoderma gangrenosum for 5 years when he developed a rheumatoid-like seronegative chronic polyarthritis. The occurrence, some time later, of a supraclavicular adenopathy led to the diagnosis of Hodgkin's disease. To our knowledge, the pyoderma-chronic polyarthritis-Hodgkin's lymphoma association has never been reported. Treatment of the lymphoma resulted in complete disappearance of cutaneous and articular symptoms. The fact that neither the skin disease nor the polyarthritis recurred during a 3-year follow-up after treatment was discontinued, incites us to discuss the possibility that the pyoderma and the polyarthritis observed in this patient were neoplastic diseases.
Flipo
R M
RM
Clinique Rhumatologique, Hôpital de la Charité, Lille.
Hardouin
P
P
Walter
M P
MP
Thomas
P
P
Bauters
F
F
Duquesnoy
B
B
D001168:Arthritis / Q000150:complications*; D002908:Chronic Disease; D006689:Hodgkin Disease / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011711:Pyoderma / Q000150:complications*
Pyoderma gangrenosum et polyarthrite chronique paranéoplasiques révélateurs d'une maladie de Hodgkin.