The blind loop syndrome in children.
Anatomical abnormalities of the small bowel that cause intestinal stagnation result in bacterial overgrowth and a blind loop syndrome (BLS). Bacterial breakdown of bile salts and deamination of protein lead to malabsorption, steatorrhea, and fat-soluble vitamin deficiencies. Four children developed BLS as a complication of necrotizing enterocolitis, jejunal atresia, gastroschisis, and biliary atresia. BLS was suggested by abdominal pain, feculent vomiting, steatorrhea, and hypoalbuminemia. Dilated, stagnant bowel loops were demonstrated in each instance by upper gastrointestinal contrast study. Positive intestinal bacterial aspirates were confirmatory. Antibiotic treatment in two patients improved symptomatology but all children ultimately required surgery. Surgical procedures consisted of blind loop resection, intestinal plication, and catheterization of the bilioenteric conduit. All patients are now asymptomatic but one child suffers from parenteral nutrition-related cirrhosis and another requires chronic antibiotic therapy.
Department of Surgery, University of Colorado School of Medicine, Denver.
B A
BA
Stewart
F M
FM
Karrer
R J
RJ
Hall
J R
JR
Lilly
D001424:Bacterial Infections / Q000150:complications / Q000628:therapy; D001656:Biliary Atresia / Q000150:complications; D001765:Blind Loop Syndrome / Q000150:complications / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D002675:Child, Preschool; D005260:Female; D005769:Gastrointestinal Motility; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012086:Reoperation