Retrospective investigation of transfusion-related non-A, non-B viral hepatitis associated with M2 antigen.
A retrospective study of transfusion-related non-A, non-B viral hepatitis was conducted in seven patients. Findings showed that six recipients had been exposed to at least one unit of blood possessing a putative serological marker for non-A, non-B hepatitis, the M2 antigen or anti-M2IgM. The M2 markers were associated with non-A, non-B hepatitis that developed 3-7 weeks after transfusion. It sees increasingly probable that M2 markers may be useful for diagnosis and/or prevention of post-transfusion hepatitis.
Field
S
S
Hopkins
R
R
Davidson
J
J
Coutts
E
E
Finlayson
N D
ND
Eade
O E
OE
Nixon
S J
SJ
Parker
A C
AC
D000956:Antigens, Viral / Q000032:analysis*; D006510:Hepatitis B Antibodies / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006526:Hepatitis C / Q000276:immunology*; D018936:Hepatitis C Antigens; D006525:Hepatitis, Viral, Human / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D065227:Transfusion Reaction
D000956:Antigens, Viral; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D018936:Hepatitis C Antigens; D007074:Immunoglobulin G; D007075:Immunoglobulin M