Enzyme histochemical demonstration of hairy cell leukaemia in paraffin-embedded tissue sections.
Hairy cell leukaemia is a form of leukaemia difficult to diagnose since pancytopenia is often present. Hairy cells contain tartrate-resistant acid phosphatase, and this factor is utilised in the diagnosis of the condition. This study confirms that it is also possible to demonstrate tartrate-resistant acid phosphatase in leukaemic infiltrates in formalin fixed paraffin-embedded tissue sections.
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Therkildsen
D000135:Acid Phosphatase / Q000032:analysis*; D004796:Clinical Enzyme Tests; D006651:Histocytochemistry; D006801:Humans; D007943:Leukemia, Hairy Cell / Q000175:diagnosis*; D008099:Liver / Q000201:enzymology; D008198:Lymph Nodes / Q000201:enzymology; D010232:Paraffin; D011402:Pronase; D013154:Spleen / Q000201:enzymology; D013194:Staining and Labeling; D013644:Tartrates
D013644:Tartrates; D010232:Paraffin; D000135:Acid Phosphatase; D011402:Pronase