Renal failure in the trauma patient.
Acute renal failure is a serious complication of the resuscitation and post-traumatic critical care of the severely injured patient. Renal ischemia secondary to shock is the most common cause of post-traumatic renal failure. The unrecognized or untreated renal ischemic state can lead to nephrotoxic damage in the post-traumatic patient. Prevention of acute failure by rapid resuscitation and restoration of circulating volume to prevent ongoing renal ischemia and prerenal azotemia is imperative for reducing the incidence of post-traumatic renal failure. Once post-traumatic renal failure is established, aggressive dialysis can reduce the mortality resulting from post-traumatic renal failure.
Department of Anesthesia, Pennsylvania State University School of Medicine, Hershey 17033.
J K
JK
Stene
D058186:Acute Kidney Injury / Q000517:prevention & control* / Q000628:therapy; D003422:Critical Care; D006801:Humans; D012151:Resuscitation; D014947:Wounds and Injuries / Q000150:complications*