Cholinergic urticaria shows neutrophilic inflammation.
Three patients with cholinergic urticaria were studied by biopsy and neutrophilic urticaria was observed in two. Direct immunofluorescence was negative in 1 patient, and monoclonal antibody studies identified a large population of OKM-1 antibody positive cells.
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Winkelmann
D000911:Antibodies, Monoclonal; D001007:Anxiety / Q000150:complications; D001706:Biopsy; D003872:Dermatitis / Q000473:pathology*; D005455:Fluorescent Antibody Technique; D006358:Hot Temperature / Q000009:adverse effects; D006801:Humans; D009504:Neutrophils / Q000473:pathology*; D005082:Physical Exertion; D014581:Urticaria / Q000209:etiology / Q000473:pathology*
D000911:Antibodies, Monoclonal