Water vapour loss threshold and induction of cholinergic urticaria.
A patient is described with cholinergic urticaria (CU) in whom the symptoms could be provoked by gustatory stimuli. The aim of this study was to investigate whether there is a threshold of sweating (monitored by skin water vapour loss (SVL) measurements) at which CU can be provoked. Provocations with lemon and sal-ammoniac liquorice induced transient sweating differing both in degree and duration. Only 'doubly salted' liquorice, which caused the most intense sweat response, resulted in urticarial lesions. This findings suggest a threshold dependency for the induction of CU. SVL measurement may be a useful method for the evaluation of sweating tests in CU patients.
Tupker
R A
RA
Dermatology Department, State University Hospital, Groningen, The Netherlands.
Doeglas
H M
HM
D001834:Body Water / Q000502:physiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D010275:Parasympathetic Nervous System / Q000503:physiopathology; D013546:Sweating / Q000502:physiology*; D013547:Sweating, Gustatory / Q000503:physiopathology; D014581:Urticaria / Q000209:etiology* / Q000503:physiopathology