[Thrombocytopenia induced by heparin and cardiac surgery with extracorporeal circulation].
A case of mitral and aortic valvular replacement combined with double coronary artery bypass grafting is reported in a 64-year-old woman who presented with a history of heparin-induced thrombocytopenia. The use of a conventional dose of heparin did not induce the formation of a plasma platelet-aggregation factor. The necessity of postoperative anticoagulation was ensured by the prescription of antivitamin K, started on the morning of the operative day.
Lugrin
D
D
Département d'Anesthésiologie, Hôpital Saint-Roch, Nice.
Isetta
C
C
Roul
C
C
Kotaiche
M
M
Jourdan
J
J
D001779:Blood Coagulation Factors / Q000302:isolation & purification; D006348:Cardiac Surgical Procedures; D005112:Extracorporeal Circulation; D005260:Female; D006493:Heparin / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D010972:Platelet Activating Factor; D010974:Platelet Aggregation / Q000187:drug effects; D011184:Postoperative Period; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000276:immunology; D014812:Vitamin K / Q000037:antagonists & inhibitors
D001779:Blood Coagulation Factors; D010972:Platelet Activating Factor; D014812:Vitamin K; D006493:Heparin
Thrombopénie induite par l'héparine et chirurgie cardiaque sous circulation extracorporelle.