Raised C-reactive protein levels in serum from smokers.
Investigation of a possible quantitative relationship between the extent of tissue injury due to inhalation of tobacco smoke and changes in concentrations of a number of acute phase proteins were studied in smokers. Smokers showed an acute phase response as indicated by significantly raised serum C-reactive protein levels. Significant lowering of serum albumin levels was also observed in smokers. Serum levels of alpha 1-antitrypsin, alpha 1-antichymotrypsin, alpha 1-acid glycoprotein, transferrin and haptoglobin did not show any significant changes due to inhalation of tobacco smoke. Although the C-reactive protein test is non-specific, evidence for elevated levels of C-reactive protein indicates the presence of tissue inflammation.
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D000209:Acute-Phase Proteins; D000328:Adult; D001798:Blood Proteins / Q000032:analysis; D002097:C-Reactive Protein / Q000032:analysis*; D005260:Female; D006801:Humans; D007249:Inflammation / Q000097:blood; D008297:Male; D012907:Smoking
D000209:Acute-Phase Proteins; D001798:Blood Proteins; D002097:C-Reactive Protein