Urinary excretion of 5-S-cysteinyldopa and 6-hydroxy-5-methoxyindole-2-carboxylic acid: differences between pigmented and albino mice.
Urinary excretion of the phaeomelanin precursor 5-S-cysteinyldopa (5-S-CD) and the eumelanin metabolite 6-hydroxy-5-methoxyindole-2-carboxylic acid (6H5MI-2-C) was studied in black and albino mice. The urinary concentration of 5-S-CD was 31.7 ng/ml in black and 16.1 ng/ml in albino mice. The concentration of 6H5MI-2-C was 21.0 ng/ml in the urine of black mice. The compound could not be demonstrated in the urine of albino mice.
M C
MC
Ekelund
R
R
Carstam
C
C
Hansson
H
H
Rorsman
E
E
Rosengren
D000417:Albinism / Q000652:urine*; D000818:Animals; D003548:Cysteinyldopa / Q000652:urine; D005260:Female; D007211:Indoles / Q000652:urine; D051379:Mice; D008810:Mice, Inbred C57BL; D008815:Mice, Inbred Strains; D012016:Reference Values
D007211:Indoles; D003548:Cysteinyldopa; C017408:6-hydroxy-5-methoxy-2-indolylcarboxylic acid