[Synthesis of the isocamphene series. 33. The synthesis of fungicidal norbornane derivatives].
Starting from the corresponding amines the syntheses of various norbornyl ureas with potential fungicidal activity are described. These new compounds possess a tricyclo[5.2.1.0(2,6)]decane, or an isocamphenilane, a camphenilane, an exo- and endo- dimethylnorbornane or a bicyclo[2.2.2]octane carbon skeleton. With the exception of the first class all other derivatives bear a geminal dimethyl group--important because of its shielding effect--at C-3 of the bicyclus. Some ureas, especially 6 and the acetamide 5, are active against phytopathogenic fungi.
Institut für Pharmazeutische Chemie der Universität, Wien.
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Buchbauer
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Spreitzer
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Püringer
D001203:Ascomycota / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D005659:Fungicides, Industrial / Q000138:chemical synthesis*; D008826:Microbial Sensitivity Tests; D009636:Norbornanes / Q000138:chemical synthesis* / Q000494:pharmacology
D005659:Fungicides, Industrial; D009636:Norbornanes
Synthesen in der Isocamphanreihe, 33. Mitt.: Zur Synthese von fungizid wirksamen Norbornanderivaten.