Cutaneous T-cell lymphoma in a patient infected with human immunodeficiency virus type 1. Use of radiation therapy.
A patient with cutaneous T-cell lymphoma (CTCL) and acquired immune deficiency syndrome (AIDS) is presented. The patient had a localized lesion on his scalp. Evaluation for systemic lymphoma was negative. A biopsy specimen showed superficial and deep dermal infiltrates of pleomorphic lymphocytes. Immunohistochemistry was consistent with T-cell lymphoma. The patient was treated successfully with local irradiation. He remained free of further systemic and cutaneous recurrences of the lymphoma until he died 8 months after treatment of pneumonia. This case is the first to our knowledge to describe a localized CTCL in a patient infected with human immunodeficiency virus type 1 (HIV-1).
Department of Radiation Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York.
J
J
Goldstein
N
N
Becker
J
J
DelRowe
L
L
Davis
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D015497:HIV-1; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000209:etiology / Q000473:pathology / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D012535:Scalp / Q000473:pathology / Q000528:radiation effects; D012878:Skin Neoplasms / Q000209:etiology / Q000473:pathology / Q000532:radiotherapy*; D013601:T-Lymphocytes / Q000473:pathology