[Participation of cyclic nucleotides and calcium in regulation of the sensitivity of vertebrate photoreceptors].
Effects of PDE inhibitor IBMX and of Ca2+ decrease upon sensitivity of rods and cones were compared. IBMX greatly increases the sensitivity of rods but not that of cones. Ca2+ does not significantly affect the sensitivity of both rods and cones. Possible role of cyclic nucleotides as feed--back regulator in mechanisms of photoreception is discussed.
Bochkin
L M
LM
Zak
P P
PP
Ostrovskii
M A
MA
D015056:1-Methyl-3-isobutylxanthine / Q000494:pharmacology; D000818:Animals; D002118:Calcium / Q000502:physiology*; D010856:Columbidae; D003623:Dark Adaptation / Q000187:drug effects; D009712:Nucleotides, Cyclic / Q000502:physiology*; D010786:Photoreceptor Cells / Q000502:physiology*; D011896:Rana temporaria; D012911:Snakes
D009712:Nucleotides, Cyclic; D002118:Calcium; D015056:1-Methyl-3-isobutylxanthine
Ob uchastii tsiklicheskikh nukleotidov i kal'tsiia v reguliatsii chuvstvitel'nosti fotoretseptorov pozvonochnykh.