Whipple's disease in an HLA-B27 positive female.
The first reported case of Whipple's disease in a female who was HLA-B27 positive and had asymptomatic sacroiliitis is discussed. She presented great difficulty in diagnosis as she had multi-system involvement without diarrhea. This case supports the hypothesis that Whipple's disease is a disorder related to HLA-B27.
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D000890:Anti-Infective Agents / Q000627:therapeutic use; D001168:Arthritis / Q000150:complications; D001706:Biopsy; D002701:Chloramphenicol / Q000627:therapeutic use; D004338:Drug Combinations / Q000627:therapeutic use; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D015796:HLA-B27 Antigen; D006801:Humans; D007421:Intestine, Small / Q000473:pathology; D008198:Lymph Nodes / Q000648:ultrastructure; D008199:Lymphadenitis / Q000150:complications; D008875:Middle Aged; D011859:Radiography; D012446:Sacroiliac Joint / Q000000981:diagnostic imaging; D012737:Sex Factors; D013420:Sulfamethoxazole / Q000627:therapeutic use; D014295:Trimethoprim / Q000627:therapeutic use; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D008061:Whipple Disease / Q000150:complications / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology
D000890:Anti-Infective Agents; D004338:Drug Combinations; D006680:HLA Antigens; D015796:HLA-B27 Antigen; D002701:Chloramphenicol; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim; D013420:Sulfamethoxazole