Expression of differentiated functions in kidney epithelial cell lines.
The expression of differentiated functions in long-term cell lines MDCK and LLC-PK1 derived from renal epithelia is briefly summarized. Topics include differentiated transport properties and enzymatic functions expressed by these cell lines, modulation of a differentiated phenotype by exogenous inducers, substratum and cell-cell contact, and possible mechanisms of inducer action.
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JE
Lever
D000081:Acetamides / Q000494:pharmacology; D000818:Animals; D002450:Cell Communication; D002454:Cell Differentiation; D002460:Cell Line; D002999:Clone Cells; D003470:Culture Media; D000242:Cyclic AMP / Q000378:metabolism; D004121:Dimethyl Sulfoxide / Q000494:pharmacology; D004126:Dimethylformamide / Q000494:pharmacology; D004285:Dogs; D004847:Epithelial Cells; D006867:Hydrolases / Q000378:metabolism; D007473:Ion Channels / Q000378:metabolism; D007684:Kidney Tubules / Q000166:cytology / Q000201:enzymology / Q000378:metabolism*; D007687:Kidney Tubules, Proximal / Q000166:cytology / Q000201:enzymology / Q000378:metabolism*; D008871:Microvilli / Q000201:enzymology / Q000378:metabolism; D009004:Monosaccharide Transport Proteins / Q000378:metabolism; D010641:Phenotype; D012964:Sodium / Q000378:metabolism; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism; D013552:Swine
D000081:Acetamides; D003470:Culture Media; D007473:Ion Channels; D009004:Monosaccharide Transport Proteins; D004126:Dimethylformamide; D012964:Sodium; D000242:Cyclic AMP; D006867:Hydrolases; D000254:Sodium-Potassium-Exchanging ATPase; C014026:hexamethylene bisacetamide; D004121:Dimethyl Sulfoxide