Single non-inactivating K+ channels in the myotubes of the chick embryo in tissue culture.
Single-channel K+ currents were studied in the myotubes from the chick embryo grown in tissue culture for 4--9 days by employing the patch clamp technique. The "cell attached" configuration was used and the pipette was filled with a solution containing 3 mmol.l-1 K+. The channels exhibited a high conductance of approximately 90 pS and the probability of finding them open increased by an e-fold factor for 13 mV depolarization for low levels of activity. The channels did not inactivate during long-lasting depolarization. These channels have been suggested to contribute to delayed rectification.
L
L
Vyklický
L
L
Vyklický
F
F
Vyskocil
E
E
Ujec
J
J
Michl
V
V
Vlachová
D000818:Animals; D002642:Chick Embryo; D007473:Ion Channels / Q000032:analysis*; D008564:Membrane Potentials; D009132:Muscles / Q000032:analysis* / Q000196:embryology; D013997:Time Factors
D007473:Ion Channels