Immunohistochemical and immunochemical characterization of a new endothelial cell-specific antigen.
A new monoclonal antibody (moab BW 200) of IgG3 kappa-isotype was generated which recognizes an epitope located on an antigen molecule restricted to human neoplastic and non-neoplastic endothelial cells. The molecular weight of the antigen was determined using immunoprecipitation analysis followed by SDS-PAGE. Despite its similar molecular weight to FVIII-RAG, the antigen detected by moab BW 200 was shown to be different from FVIII-RAG.
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Alles
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Bosslet
D000911:Antibodies, Monoclonal / Q000276:immunology; D000941:Antigens / Q000032:analysis*; D001808:Blood Vessels / Q000276:immunology*; D004727:Endothelium / Q000276:immunology; D000939:Epitopes / Q000032:analysis; D005169:Factor VIII / Q000032:analysis / Q000276:immunology; D006651:Histocytochemistry; D006801:Humans; D007120:Immunochemistry; D008970:Molecular Weight; D014841:von Willebrand Factor
D000911:Antibodies, Monoclonal; D000941:Antigens; D000939:Epitopes; D014841:von Willebrand Factor; D005169:Factor VIII