[Immunogenetic analysis of delayed hypersensitivity to tuberculin in mice by the method of local adoptive transfer].
It has been demonstrated that a specific phase of DTH reaction to tuberculin is carried out (and in adoptive transfer-transferred) by T-lymphocytes with Lyt-1+, Lyt-2-, L3T4+ phenotype by a method of local adoptive transfer of this reaction from BCG-immunized mice to the pads of intact recipients. From genetic viewpoint, the above reaction is limited by 1-A beta, 1-A alpha genes. In a syngeneic apposition, monoclonal antibodies anti-1-A kappa beta (without complement) were blocking the reaction transfer to CBA mice A beta chain affected mutation bm12 failed to limit the reaction transfer in apposition B6----B6.C-H-2bm12.
Mezhlumova
M B
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D000818:Animals; D001500:BCG Vaccine / Q000276:immunology*; D006968:Hypersensitivity, Delayed / Q000209:etiology* / Q000235:genetics / Q000276:immunology; D007116:Immunization, Passive / Q000379:methods*; D051379:Mice; D008815:Mice, Inbred Strains; D010641:Phenotype; D013601:T-Lymphocytes / Q000276:immunology*; D014373:Tuberculin / Q000276:immunology*; D014374:Tuberculin Test / Q000379:methods
D001500:BCG Vaccine; D014373:Tuberculin
Immunogeneticheskiĭ analiz giperchuvstvitel'nosti zamedlennogo tipa k tuberkulinu u mysheĭ metodom lokal'nogo adoptivnogo perenosa.