Orcein-positive material in Kupffer cells from the liver.
Orcein-positive material in Kupffer cells obtained from 1,377 needle biopsies of the liver was studied for hepatitis B surface antigen (HBsAg). Fifty-five (57%) out of 96 cases with orcein-positive Kupffer cells had acute hepatitis, and 46 (84%) of these 55 were in the late stage of their illness. Orcein-positive material in Kupffer cells was not associated with HBsAg as evaluated by the immune peroxidase method. Orcein-positive material in Kupffer cells appears to consist mainly of lipofuscins developing in the course of acute hepatitis.
Uehara
C
C
Sakurai
M
M
Ishizu
H
H
Mitsutani
N
N
Koizumi
T
T
D000208:Acute Disease; D006505:Hepatitis / Q000276:immunology; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006801:Humans; D007728:Kupffer Cells / Q000032:analysis*; D008062:Lipofuscin / Q000032:analysis; D008099:Liver / Q000473:pathology; D010078:Oxazines; D013194:Staining and Labeling
D006514:Hepatitis B Surface Antigens; D008062:Lipofuscin; D010078:Oxazines; C002313:PAcein