Sudden death following accidental ingestion of chlormequat.
A 59-year-old white male accidentally ingested a mouthful of a plant growth chemical, Cycocel, containing 11.8% of the active ingredient (2-chloroethyl)trimethylammonium chloride (chlormequat). He was seen by a family physician and then transferred to a hospital where he died as a result of ventricular fibrillation, which progressed to asystole. Postingestion symptoms were typical of cholinergic crisis and included salivation, diaphoresis, bradycardia, visual disturbances, and seizure. Autopsy findings showed marked pulmonary edema, coronary atherosclerosis, atheromata of aorta, and localized adenocarcinoma of the prostate. Toxicological analyses of biological samples showed the presence of chlormequat in the stomach contents and urine.
Allegheny County Department of Laboratories, Pittsburgh, Pennsylvania 15219.
C L
CL
Winek
W W
WW
Wahba
J M
JM
Edelstein
D000062:Accidents, Occupational; D002716:Chlormequat / Q000378:metabolism / Q000506:poisoning*; D003645:Death, Sudden / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D000644:Quaternary Ammonium Compounds / Q000506:poisoning*
D000644:Quaternary Ammonium Compounds; D002716:Chlormequat