"In vitro" effects of bovine growth hormone on RNA labelling in brain and liver slices of neonatal hypothyroid rats.
The present studies were performed in order to analize the "in vitro" effects of bovine growth hormone upon the RNA labelling slices from cerebrum and liver of neonatal hypothyroid rats. The [3H]-uridine incorporation was significantly enhanced by bovine growth hormone in both tissues. The stimulation was higher in liver than in cerebrum. The present results confirm the direct action of growth hormone on the RNA synthesis in liver and cerebrum during the postnatal development of the rat.
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Krawiec
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Berti-Mattera
D000818:Animals; D000831:Animals, Newborn; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D005260:Female; D013006:Growth Hormone / Q000494:pharmacology*; D007037:Hypothyroidism / Q000378:metabolism*; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D012313:RNA / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D012313:RNA; D013006:Growth Hormone