[Precipitating monoclonal antibodies to 1 of the antigenic determinants of streptococcal group-A polysaccharide].
Monoclonal antibodies (MCA) to streptococcal group A polysaccharide (A-PS) were prepared. Precipitating MCA are directed to the determinant common for A-PS and streptococcal group L polysaccharide (L-PS). The antibodies react in the immunodiffusion test and give identity reaction in A- and L-PS tests. Other MCA are non-precipitating but react with A-PS studied by immunoenzyme method. The reasons for the formation of precipitating and non-precipitating MCA to different antigenic determinants of A-PS are discussed.
Drobyshevskaia
E I
EI
Borodiiuk
N A
NA
Kolesnikova
V Iu
VIu
Liampert
I M
IM
D000818:Animals; D000911:Antibodies, Monoclonal / Q000032:analysis / Q000302:isolation & purification*; D000939:Epitopes / Q000276:immunology*; D006825:Hybridomas / Q000276:immunology; D007114:Immunization; D005779:Immunodiffusion; D007124:Immunoenzyme Techniques; D051379:Mice; D008807:Mice, Inbred BALB C; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D011233:Precipitin Tests; D011817:Rabbits; D013297:Streptococcus pyogenes / Q000276:immunology*
D000911:Antibodies, Monoclonal; D000939:Epitopes; D011135:Polysaccharides, Bacterial
Pretsipitiruiushchie monoklonal'nye antitela k odnoĭ iz antigennykh determinant polisakharida streptokokka gruppy A.