Use of cultured epidermal autografts and dermal allografts as skin replacement after burn injury.
An adult with burns over 55% of body surface area (80% of which were third degree) was treated with cadaver skin allografts. The allografts were later abraded to remove allogeneic epidermis and resurfaced with autogenous keratinocyte cultures. Complete reconstitution of skin, consisting of epidermal autograft and dermal allograft, was achieved.
Cuono
C
C
Langdon
R
R
McGuire
J
J
D002056:Burns / Q000601:surgery*; D002102:Cadaver; D002478:Cells, Cultured; D000078404:Epidermal Cells; D004817:Epidermis / Q000637:transplantation*; D006801:Humans; D007633:Keratins; D008297:Male; D008875:Middle Aged; D016038:Skin Transplantation; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous
D007633:Keratins