[Isovolemic hemodilution--an adjuvant treatment principle in patients with chronic cor pulmonale caused by chronic obstructive lung disease].
On the basis of 10 patients with chronic cor pulmonale due to chronic obstructive lung disease and secondary polyglobulia in a clinical and experimental study could be made evident that by limited isovolaemic haemodilution (haematocrit value of 0.58 +/- 0.03 reduced to 0.36 +/- 0.01) are to be expected a decrease of the total pulmonary-arterial resistance, a reduction of the mean pulmonary arterial pressure, an increase of the partial O2-pressure as well as an increase of the heart index. Analogically to this as a consequence of the improved rheologic conditions a clear involution of the clinical signs of a heart insufficiency developed. Complications were not observed. The technique of the limited haemodilution should find a broader use in the medical practice, taking into consideration the isovolaemia as adjuvant treatment principle for patients with the indication mentioned.
Klinik für Innere Medizin, Bezirkskrankenhauses St. Georg Leipzig.
G
G
Thiele
I
I
Bürkmann
K
K
Ziesenhenn
B
B
Herold
D001810:Blood Volume / Q000502:physiology; D006333:Heart Failure / Q000628:therapy; D006438:Hemodilution / Q000379:methods*; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000150:complications*; D010100:Oxygen / Q000097:blood; D011660:Pulmonary Heart Disease / Q000628:therapy*
D010100:Oxygen
Die isovolämische Hämodilution--ein adjuvantes Behandlungsprinzip bei Patienten mit Cor pulmonale chronicum infolge chronisch obstruktiver Lungenkrankheit.