Heparin action in pemphigus vulgaris: clinical and immunologic studies.
Heparin administration to 34 patients with pemphigus vulgaris before the beginning of steroid treatment or in combination with it proved to be therapeutically useful. Its suppressive effect on T- and B-lymphocytes in vitro and in vivo was revealed in the examined patients by the test of rosette-formation.
Mashkilleyson
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D000328:Adult; D000368:Aged; D001402:B-Lymphocytes / Q000166:cytology / Q000276:immunology; D004359:Drug Therapy, Combination; D005260:Female; D006493:Heparin / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D010392:Pemphigus / Q000188:drug therapy / Q000276:immunology*; D012397:Rosette Formation; D013256:Steroids / Q000008:administration & dosage / Q000627:therapeutic use; D013601:T-Lymphocytes / Q000166:cytology / Q000276:immunology
D013256:Steroids; D006493:Heparin