Plasma 5-S-cysteinyldopa concentrations in oculocutaneous albinism.
5-S-cysteinyldopa concentrations were determined by high-pressure liquid chromatography and electrochemical detection in plasma from normally pigmented patients and patients with oculocutaneous albinism, both tyrosinase-positive and tyrosinase-negative. The plasma 5-S-cysteinyldopa concentrations were similar in all three groups, suggesting that 5-S-cysteinyldopa can be produced by mechanisms which do not involve tyrosinase.
Nimmo
J E
JE
Hunter
J A
JA
Percy-Robb
I W
IW
Jay
B
B
Phillips
C I
CI
Taylor
W O
WO
D000417:Albinism / Q000097:blood* / Q000145:classification / Q000378:metabolism; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D003548:Cysteinyldopa / Q000096:biosynthesis / Q000097:blood*; D004295:Dihydroxyphenylalanine / Q000031:analogs & derivatives*; D004563:Electrochemistry; D005260:Female; D006801:Humans; D008297:Male; D008543:Melanins / Q000378:metabolism; D051379:Mice; D014442:Monophenol Monooxygenase / Q000378:metabolism; D051381:Rats
D008543:Melanins; D003548:Cysteinyldopa; D004295:Dihydroxyphenylalanine; D014442:Monophenol Monooxygenase