A nerve cuff technique for selective excitation of peripheral nerve trunk regions.
Numerical modeling and experimental testing of a nerve cuff technique for selective stimulation of superficial peripheral nerve trunk regions is presented. Two basic electrode configurations ("snug" cuff monopolar and tripolar longitudinally aligned dots) have been considered. In addition, the feasibility of "steering" excitation into superficial nerve trunk regions using subthreshold levels of current flow from an electrode dot located on the opposite side of the nerve has been tested. Modeling objectives were to solve for the electric field that would be generated within a representative nerve trunk by each electrode configuration; and to use a simple nerve cable model to predict the effectiveness of each configuration in producing localized excitation. In three acute experiments on cat sciatic nerve the objective was to characterize the effectiveness of each electrode configuration in selectively activating only the medial gastrocnemius muscle. Modeling and experimentation both suggest that longitudinally aligned tripolar dot electrodes on the surface of a nerve trunk, and bounded by a layer of insulation (such as a nerve cuff), will restrict excitation to superficial nerve trunk regions more successfully than will monopolar dot electrodes. Excitation "steering" will improve the spatial selectivity of both monopolar and tripolar electrode configurations.
Sweeney
J D
JD
Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106.
Ksienski
D A
DA
Mortimer
J T
JT
D000818:Animals; D002415:Cats; D004558:Electric Stimulation / Q000379:methods; D004566:Electrodes; D007537:Isometric Contraction / Q000502:physiology; D008959:Models, Neurological; D010525:Peripheral Nerves / Q000502:physiology*