[Basic nuclear proteins of transition during spermiogenesis in Scylliorhinus caniculus].
During dog-fish spermiogenesis, 2 basic nuclear protein transitions occur: the first from histones to spermatid-specific proteins S1 and S2, the second leading to protamines. S1, the most abundant transition protein, is a polypeptide containing 87 residues (Mr = 11,179 Da) whereas S2, the minor transition protein, contains 80 residues (Mr = 9,726 Da). The 2 proteins are mainly characterized by an asymmetry of the molecule, a very high content of basic residues, a relatively high level of hydrophobic residues and a cluster of acidic residues in the carboxy-terminal quarter of the molecule. The 2 proteins are phosphorylated on serine residues and the degree of phosphorylation is relatively important in protein S1. The 2 transition proteins are structurally unrelated to testis histones or sperm protamines and cannot be considered either as their proteolytic degradation products or as their precursors.
Chauvière
M
M
Université Paris-Val de Marne, laboratoire de biologie cellulaire, Créteil, France.
Martinage
A
A
Sautière
P
P
Chevaillier
P
P
D000595:Amino Acid Sequence; D000818:Animals; D002868:Chromosomal Proteins, Non-Histone / Q000378:metabolism; D004284:Dogfish / Q000378:metabolism*; D006657:Histones / Q000378:metabolism; D008297:Male; D008969:Molecular Sequence Data; D009687:Nuclear Proteins / Q000378:metabolism*; D010766:Phosphorylation; D010768:Phosphoserine / Q000378:metabolism; D011479:Protamines / Q000378:metabolism; D012754:Sharks / Q000378:metabolism*; D013091:Spermatogenesis / Q000502:physiology*
D002868:Chromosomal Proteins, Non-Histone; D006657:Histones; D009687:Nuclear Proteins; D011479:Protamines; C053886:spermatid transition proteins; D010768:Phosphoserine
Les protéines nucléaires basiques de transition au cours de la spermiogenèse de la roussette Scylliorhinus caniculus.