[The occurrence of goitrogenic substances in milk. 1. Release of goitrin in the milk of cows fed on rapeseed extract cakes].
A total of six cows, divided into 3 groups, were fed various amounts of rape cake containing 6 g of goitrin/kg over a period of 7 days. The cows were milked twice a day and the goitrin content of the heated milk samples were determined by a HPLC-method within 2 h. When rape cake was fed at 0.39, 1.9 and 3.9% resp. of the total feed this resulted in medium goitrin values of 37, 163 and 707 micrograms/l milk. These values correspond to a transfer of about 0.1% of the original progoitrin content in the feed. 12 h after the last rape feeding the amount of goitrin in the milk was below the detection limit of 7 ppb. The toxicological significance of these findings are dicussed.
M
M
Bachmann
R
R
Theus
J
J
Lüthy
C
C
Schlatter
D000821:Animal Feed; D000818:Animals; D013956:Antithyroid Agents / Q000032:analysis*; D001937:Brassica; D002417:Cattle; D002851:Chromatography, High Pressure Liquid; D008892:Milk / Q000032:analysis*; D010080:Oxazoles / Q000032:analysis*; D023303:Oxazolidinones; D013056:Spectrophotometry, Ultraviolet; D013997:Time Factors
D013956:Antithyroid Agents; D010080:Oxazoles; D023303:Oxazolidinones; C004333:goitrin
Vorkommen von goitrogenen Stoffen in Milch. 1. Mitteilung: Ubergang von Goitrin in die Milch von Kühen bei Verfütterung von rapsextraktionsschrot.