Shwartzman reaction in germfree rabbits.
The local Shwartzman reaction occurred in germfree rabbits which had no natural antibody to endotoxin and none or only a very small amount of immunoglobulin G. From the results it was concluded that the presence of natural antibody to endotoxin is not a prerequisite of the production of the local Shwartzman reaction by bacterial endotoxin.
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D000818:Animals; D004731:Endotoxins / Q000276:immunology; D004926:Escherichia coli / Q000276:immunology; D005260:Female; D005856:Germ-Free Life; D007422:Intestines / Q000276:immunology / Q000382:microbiology; D007958:Leukocyte Count; D008297:Male; D011817:Rabbits; D012790:Shwartzman Phenomenon / Q000276:immunology*; D012867:Skin / Q000276:immunology; D005719:gamma-Globulins / Q000032:analysis
D004731:Endotoxins; D005719:gamma-Globulins