[Hypothyroid myopathy: apropos of a case with a great increase of creatine phosphokinase, myoglobinemia and transient kidney failure].
Clinical, usually moderate myopathy, frequently develops in patients with hypothyroidism and may reveal the thyroid dysfunction. Biological signs of myolysis, essentially a, usually moderate, rise in creatine phosphokinase plasma levels, are often found. On the other hand, rhabdomyolysis seems to be exceptional in this context. We report a case where an extremely severe clinical and biological myopathy associated with transient renal failure revealed hypothyroidism due to prolonged intake of amiodarone.
Service de Médecine Interne, CMC Foch, Suresnes.
P
P
Gepner
H
H
Botto
A M
AM
Piette
P
P
Graveleau
A
A
Chapman
D058186:Acute Kidney Injury / Q000150:complications*; D000638:Amiodarone / Q000009:adverse effects*; D003402:Creatine Kinase / Q000097:blood*; D006801:Humans; D007037:Hypothyroidism / Q000139:chemically induced* / Q000150:complications / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D012206:Rhabdomyolysis / Q000150:complications* / Q000201:enzymology
D003402:Creatine Kinase; D000638:Amiodarone
Myopathie hypothyroïdienne: à propos d'un cas avec élévation majeure de la créatine phosphokinase, myoglobinémie et insuffisance rénale transitoire.