Focus on the large arteries in hypertension.
Considerable progress in the treatment of hypertension has been made in the last few years. Thanks to medical treatments, blood pressure can be reduced and the incidence of renal, cerebral, and cardiac accidents, i.e., cardiovascular morbidity and mortality can be decreased. If it is to be effective, an antihypertensive drug must induce dilation of the small arterial vessels, namely the arterioles. When these vessels are dilated, blood pressure falls. However, cardiovascular morbidity and mortality arise from accidents that occur in the large arterial vessels (coronary, intracerebral, carotid arteries), which are subject to thickening, stenosis, and ischemia. The aim of this symposium is to describe the state of the large arteries in the hypertensive patient, a subject on which few studies have been carried out in the last few years, and to propose suitable therapeutic measures to reduce cardiovascular morbidity and mortality further.
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Safar
D000818:Animals; D000959:Antihypertensive Agents / Q000494:pharmacology; D001158:Arteries / Q000187:drug effects / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*
D000959:Antihypertensive Agents