Unusual concretions in the hepatocyte rough endoplasmic reticulum of sheep given tunicamycin.
Unusual concentric laminar bodies in the RER of ovine hepatocytes treated with tunicamycin are described. These bodies are probably proteinaceous in nature and related to inhibition of protein glycosylation by tunicamycin in the RER.
S.A. Department of Agriculture, S.E. Regional Veterinary Laboratory, Naracoorte, Australia.
J W
JW
Finnie
J D
JD
O'Shea
D000818:Animals; D004721:Endoplasmic Reticulum / Q000187:drug effects*; D008099:Liver / Q000648:ultrastructure*; D008129:Lolium; D006109:Poaceae; D011041:Poisoning; D012756:Sheep; D014415:Tunicamycin / Q000009:adverse effects*
D014415:Tunicamycin