[Increased specificity of immunoenzyme analysis for diagnosing meningococcal infection].
The ELISA test system for the detection of polysaccharide antigens of meningococci, groups A and C, on the basis of the neutralization of specific antibodies has been developed. The specificity of this reaction is determined by the chemically pure preparations of group A and C meningococcal polysaccharides. The sensitivity of this test system based on the neutralization of antibodies is not inferior to that of ELISA with the use of double antiserum.
G V
GV
Zhuravleva
A A
AA
Demina
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D000942:Antigens, Bacterial / Q000032:analysis; D002555:Cerebrospinal Fluid / Q000276:immunology; D004796:Clinical Enzyme Tests / Q000379:methods*; D004797:Enzyme-Linked Immunosorbent Assay; D000939:Epitopes / Q000032:analysis; D006801:Humans; D008589:Meningococcal Infections / Q000175:diagnosis*; D009345:Neisseria meningitidis / Q000276:immunology; D009500:Neutralization Tests; D011817:Rabbits
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D000939:Epitopes
Povyshenie spetsifichnsoti immunofermentnogo analiza dlia diagnostiki meningokokkovoĭ infektsii.