Epidermolysis bullosa acquisita antigen is synthesized by human keratinocytes cultured in serum-free medium.
The epidermolysis bullosa acquisita antigen is a newly discovered major extracellular matrix component within basement membranes beneath stratified squamous epithelia. Human keratinocytes cultured without mesenchymal cells synthesize the major 290 kd chain of the epidermolysis bullosa acquisita antigen.
Woodley
D T
DT
Briggaman
R A
RA
Gammon
W R
WR
O'Keefe
E J
EJ
D000328:Adult; D000941:Antigens / Q000302:isolation & purification*; D001485:Basement Membrane / Q000276:immunology; D002478:Cells, Cultured; D003470:Culture Media; D004591:Electrophoresis, Polyacrylamide Gel; D004820:Epidermolysis Bullosa / Q000276:immunology*; D006801:Humans; D007633:Keratins; D008970:Molecular Weight; D012867:Skin / Q000276:immunology*
D000941:Antigens; D003470:Culture Media; D007633:Keratins