Isolation, crystallization and preliminary X-ray diffraction data of human progastricsin.
Human progastricsin, a zymogen of one of the gastric aspartic proteinases, was isolated and crystallized. The crystals belong to the tetragonal space group P4(2)2(1)2, and have unit cell dimensions a = b = 105.5 +/- 0.1 A, c = 70.6 A. The native crystals of progastricsin diffract X-rays at least to 2.5 A and are suitable for a high-resolution X-ray analysis.
All-Union Cancer Research Centre, Moscow, USSR.
P K
PK
Ivanov
M M
MM
Chernaya
A E
AE
Gustchina
I V
IV
Pechik
S V
SV
Nikonov
N I
NI
Tarasova
D003460:Crystallization; D004591:Electrophoresis, Polyacrylamide Gel; D005753:Gastric Mucosa / Q000201:enzymology*; D006801:Humans; D007527:Isoenzymes / Q000302:isolation & purification*; D010435:Pepsinogens / Q000302:isolation & purification*; D011487:Protein Conformation; D014961:X-Ray Diffraction / Q000379:methods
D007527:Isoenzymes; D010435:Pepsinogens