The polymerase chain reaction: current and future clinical applications.
The polymerase chain reaction has undergone rapid improvement since its initial development, such that the technique currently permits rapid, accurate, predictive tests to be made in the field of prenatal diagnosis and has greatly aided forensic medicine. It is anticipated that the polymerase chain reaction will also facilitate advances in other fields, in particular preimplantation diagnosis, virology, bacteriology, and cancer therapy.
Lynch
J R
JR
Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Headington, Oxford.
Brown
J M
JM
D000755:Anemia, Sickle Cell / Q000235:genetics; D047108:Embryonic Development / Q000235:genetics; D005260:Female; D005554:Forensic Medicine; D005784:Gene Amplification; D015497:HIV-1 / Q000302:isolation & purification; D006801:Humans; D008828:Microbiological Techniques; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods