[Endogenous Na, K-ATPase inhibitors and biochemical markers of hypertension].
Molecular mechanisms of disturbances in the system responsible for ion transport taking place in the development of the initial hypertension in linear animals have been analysed in this review. On the basis of own and literary data the diagnostic significance of the biochemical parameters which characterize the membrane ion transport state at given disease is estimated. Using the results of correlation analysis of facts which characterize the connection between the human hypertension and specific blood factors, a probability of hypertension development depending on the degree of the given factors expression is determined.
A A
AA
Boldyrev
E A
EA
Rogaeva
D000818:Animals; D001692:Biological Transport; D001773:Blood Cells / Q000201:enzymology; D001794:Blood Pressure; D001798:Blood Proteins / Q000378:metabolism; D002463:Cell Membrane Permeability; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000209:etiology / Q000378:metabolism*; D007473:Ion Channels / Q000187:drug effects / Q000378:metabolism; D007668:Kidney / Q000201:enzymology / Q000503:physiopathology; D011188:Potassium / Q000378:metabolism; D051381:Rats; D011918:Rats, Inbred SHR; D012964:Sodium / Q000378:metabolism; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D013312:Stress, Physiological / Q000503:physiopathology
D001798:Blood Proteins; D007473:Ion Channels; D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase; D011188:Potassium
Endogennye ingibitory Na, K-ATFazy i biokhimicheskie markery gipertonii.