Effects of pH on the toxicity and uptake of [14C]lindane in the midge, Chironomus riparius.
The toxicity of the insecticide, lindane, was measured in the midge, Chironomus riparius, at pH 4, 6, and 8 with the finding that lindane is significantly more toxic at pH 6 than at pH 4 and 8. The higher toxicity of lindane at pH 6 is a product of two factors. First the penetration of the compound into the midge is lower at pH 4 than at pH 6 and 8. Second, a greater percentage of total radioactivity is contributed by parent compound at pH 6.
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D000818:Animals; D002250:Carbon Radioisotopes; D002683:Chironomidae / Q000378:metabolism*; D004175:Diptera / Q000378:metabolism*; D001556:Hexachlorocyclohexane / Q000378:metabolism / Q000633:toxicity*; D006863:Hydrogen-Ion Concentration; D007700:Kinetics
D002250:Carbon Radioisotopes; D001556:Hexachlorocyclohexane