Primary structure of human salivary alpha-amylase gene.
A recombinant clone which covers the human salivary alpha-amylase gene in a single insert has been isolated from a human genomic DNA library using a human salivary alpha-amylase cDNA as a probe. Restriction mapping and nucleotide (nt) sequence analysis revealed that this gene is approx. 10 kb long and is separated into eleven exons by ten introns. Its 5'-flanking region has some sequence homology with that of mouse salivary alpha-amylase gene [Schibler et al., J. Mol. Biol. 155 (1982) 247-266].
T
T
Nishide
Y
Y
Nakamura
M
M
Emi
T
T
Yamamoto
M
M
Ogawa
T
T
Mori
K
K
Matsubara
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000032:analysis; D004262:DNA Restriction Enzymes; D005796:Genes; D006801:Humans; D008099:Liver / Q000201:enzymology; D051379:Mice; D008854:Microscopy, Electron; D008970:Molecular Weight; D010179:Pancreas / Q000201:enzymology; D011061:Poly A / Q000235:genetics; D012313:RNA / Q000235:genetics; D012333:RNA, Messenger; D012463:Saliva / Q000201:enzymology*; D014158:Transcription, Genetic; D000516:alpha-Amylases / Q000235:genetics*
D012333:RNA, Messenger; D011061:Poly A; D012313:RNA; D004247:DNA; D004262:DNA Restriction Enzymes; D000516:alpha-Amylases