[Kallikrein inhibition of the expression of the lymphocyte E rosette receptor. Prevention of this effect by alpha-2-macroglobulin].
In vitro Kallikrein inhibits the expression of lymphocytes-E-rosetting-receptor. The preincubation of alpha-2-macroglobulin with Kallikrein prevents this effect quickly. The incubation with alpha-2-macroglobulin of Kallikrein pretreated-lymphocytes is ineffective.
J
J
Hainaut
M
M
Joussemet
J
J
Nicolas
D006801:Humans; D066298:In Vitro Techniques; D007610:Kallikreins / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology*; D011971:Receptors, Immunologic / Q000187:drug effects*; D012397:Rosette Formation; D000511:alpha-Macroglobulins / Q000494:pharmacology*
D011971:Receptors, Immunologic; D000511:alpha-Macroglobulins; D007610:Kallikreins
Inhibition par la kallicréine de l'expression du récepteur lymphocytaire des rosettes E. Prévention de cet effet par l'alpha-2-macroglobuline.