Adenomatoid tumor of the uterus. Ultrastructural, histochemical, and immunohistochemical analysis.
A uterine tumor from a 34-year-old woman was investigated morphologically and immunohistochemically. The tumor tissue was composed of multiple cystic spaces of various sizes. The cyst wall was covered by a single layer or occasionally multiple layers of flattened cells. Electron micrographs of the tumor tissue revealed that the cells were delimited with conspicuous basal lamina from the stroma, possessed numerous microvilli at the apical surface, and connected with desmosomes. Furthermore, immunohistochemical staining with antikeratin antibody disclosed the strong positivity of the tumor cells, whereas anti-UEA-I antibody could not stain the tumor cells. The results did not favor the theory of endothelial origin of the tumor and confirmed the mesothelial origin, namely, adenomatoid tumor of the uterus.
Suzuki
T
T
Yoshida
Y
Y
Kaku
T
T
Kikuchi
K
K
Mori
M
M
D000328:Adult; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D006820:Hyaluronic Acid / Q000378:metabolism; D007158:Immunologic Techniques; D007633:Keratins / Q000378:metabolism; D008654:Mesothelioma / Q000378:metabolism / Q000648:ultrastructure*; D014594:Uterine Neoplasms / Q000378:metabolism / Q000648:ultrastructure*
D007633:Keratins; D006820:Hyaluronic Acid