[Progress in immunological methods of drug quantitation in clinical laboratory].
Progress in immunological methods of drug quantitation in the clinical laboratory was discussed from three different view points, (1) Immunoassay techniques: (a) Kinds of drug to be tested, (b) Classification of tests, (c) Utilization rate of the tests and (d) Non-instrumental technique, (2) Therapeutic monitoring: (a) An example of digoxin monitoring and (b) Problems related to creatinine clearance in digoxin monitoring, (3) Development in future: (a) Identification and characterization of endogenous digoxin-like substance and (b) Application of optical isomer of drug to laboratory test.
Miura
Y
Y
Central Clinical Laboratories, Fukushima Medical College.
Yoshida
H
H
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003404:Creatinine / Q000097:blood; D004077:Digoxin / Q000008:administration & dosage / Q000493:pharmacokinetics*; D005260:Female; D006801:Humans; D007118:Immunoassay / Q000145:classification / Q000379:methods*; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D013810:Therapeutic Equivalency
D004077:Digoxin; D003404:Creatinine