Immunochemical and kinetic evidence that heparin enhances aprotinin activity.
Both immunochemical and kinetic evidence suggest that the increase in aprotinin activity in the presence of heparin is not due to an increase in the active form of aprotinin, but rather to a qualitative change in the aprotinin molecule which would lead to an increase in aprotinin activity.
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Shikimi
D000818:Animals; D007611:Aprotinin / Q000378:metabolism*; D002417:Cattle; D006493:Heparin / Q000494:pharmacology*; D007120:Immunochemistry; D066298:In Vitro Techniques; D007700:Kinetics; D013268:Stimulation, Chemical; D014357:Trypsin / Q000378:metabolism
D006493:Heparin; D007611:Aprotinin; D014357:Trypsin