The effect of epinephrine and serotonin on hepatic poly(A)+ RNA synthesis.
In vivo administration of epinephrine or serotonin has been shown to stimulate the incorporation of 14C-orotic acid into Poly(A)+ RNA. However, only epinephrine and not serotonin could stimulate DNA dependent RNA polymerase activity of isolated hepatic nuclei in in vitro experiments.
A K
AK
Roy
R
R
Bhadra
A G
AG
Datta
D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism; D002482:Cellulose / Q000031:analogs & derivatives; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism; D004837:Epinephrine / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D009838:Oligodeoxyribonucleotides; D009963:Orotic Acid / Q000378:metabolism; D011061:Poly A / Q000096:biosynthesis*; D011132:Polyribosomes / Q000378:metabolism; D012313:RNA / Q000096:biosynthesis*; D012333:RNA, Messenger; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000494:pharmacology*; D014544:Uridine Triphosphate / Q000378:metabolism
D009838:Oligodeoxyribonucleotides; D012333:RNA, Messenger; C021722:oligo(dT)-cellulose; D011061:Poly A; D012701:Serotonin; D009963:Orotic Acid; D012313:RNA; D002482:Cellulose; D012321:DNA-Directed RNA Polymerases; D014544:Uridine Triphosphate; D004837:Epinephrine