[The metabolic and phagocytic activities of the neutrophilic granulocytes in patients with nonspecific ulcerative colitis nd Crohn's disease].
Immune homeostasis is of importance in the pathogenesis of unspecific inflammatory diseases of the colon. The authors studied the state of unspecific resistance of patients with unspecific ulcerative colitis (UUC) and Crohn's disease (KD); 27 with UUC and 21 KD patients with chronic relapsing forms of the disease were examined. Patients in the acute form of the disease showed an activation of the metabolic processes in the neutrophil granulocytes that was more pronounced in UUC and a reduction of the phagocytic activity in KD. During the period of early remission these values were practically normal evidencing the prognostic value of factors of unspecific defense in unspecific inflammatory diseases of the intestine.
Blazhenko
I L
IL
Bychkova
N G
NG
Shvets
N I
NI
D000293:Adolescent; D000328:Adult; D002648:Child; D003093:Colitis, Ulcerative / Q000097:blood* / Q000276:immunology / Q000628:therapy; D003424:Crohn Disease / Q000097:blood* / Q000276:immunology / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology / Q000378:metabolism*; D010587:Phagocytosis; D012074:Remission Induction
Metabolicheskaia i fagotsitarnaia aktivnost' neĭtrofil'nykh granulotsitov u bol'nykh nespetsificheskim iazvennym kolitom i bolezn'iu Krona.