[Effect of actions inhibiting neovascularization of the metastasis of Lewis lung carcinoma].
Indomethacine, protamine-sulphate and hydrocortisone were found to decrease the activity of metastatic processes of Lewis carcinoma after the removal of the primary tumour. The most pronounced effect was observed in case of the complex application of these preparations. The effect obtained correlates with the ability of these preparations to inhibit the neovascularization.
E B
EB
Sopotsinskaia
I A
IA
Lisniak
K P
KP
Balitskiĭ
D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002277:Carcinoma / Q000098:blood supply* / Q000188:drug therapy; D004353:Drug Evaluation, Preclinical; D006854:Hydrocortisone / Q000008:administration & dosage; D007213:Indomethacin / Q000008:administration & dosage; D008175:Lung Neoplasms / Q000098:blood supply* / Q000188:drug therapy; D051379:Mice; D008810:Mice, Inbred C57BL; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D009389:Neovascularization, Pathologic; D011182:Postoperative Care; D011479:Protamines / Q000008:administration & dosage
D011479:Protamines; D006854:Hydrocortisone; D007213:Indomethacin
Vliiania vozdeĭstviĭ, ingibiruiushchikh neovaskuliarizatsiiu, na metastazirovanie kartsinomy legkikh L'iuis.