An evaluation of the TDX fluorescence polarization immunoassays for procainamide and n-acetylprocainamide.
The TDX fluorescence polarization assays (FPIA) for procainamide (PA) and n-acetylprocainamide (NAPA) were evaluated. Coefficients of variation for within- and between-assay precision studies were less than 6%. Both methods correlated well with a referenced HPLC technique; r2 values for PA and NAPA were 0.980 and 0.986, respectively.
P K
PK
Sonsalla
R R
RR
Bridges
T A
TA
Jennison
C M
CM
Smith
D000120:Acecainide / Q000032:analysis*; D001322:Autoanalysis; D002851:Chromatography, High Pressure Liquid; D005454:Fluorescence Polarization; D005455:Fluorescent Antibody Technique; D006801:Humans; D011342:Procainamide / Q000031:analogs & derivatives* / Q000032:analysis*; D011933:Reagent Kits, Diagnostic / Q000592:standards
D011933:Reagent Kits, Diagnostic; D000120:Acecainide; D011342:Procainamide