Spectrophotometric determination of oxprenolol hydrochloride as its Fe (III) complex.
A spectrophotometric determination of oxprenolol hydrochloride in pharmaceutical preparations is described. The method is based on the reaction of oxprenolol hydrochloride with Fe (III) ion in the presence of ammonium thiocyanate, in acid media. The complex formed between oxprenolol hydrochloride and Fe (III) ion was extracted with chloroform and assayed spectrophometrically at 477 nm. The results obtained are reproducible and hence the method is suitable for the determination of oxprenolol hydrochloride in pharmaceutical dosage forms.
Radulović
D
D
Institute of Pharmaceutical Chemistry, Faculty of Pharmacy, Belgrade, Yugoslavia.
Pećanac
D
D
Zivanović
L
L
Agatonović-Kustrin
S
S
D004355:Drug Stability; D005290:Ferric Compounds / Q000032:analysis*; D007202:Indicators and Reagents; D010096:Oxprenolol / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet; D013607:Tablets
D005290:Ferric Compounds; D007202:Indicators and Reagents; D013607:Tablets; D010096:Oxprenolol