[Morphological study of the disruption of the blood-aqueous barrier following paracentesis].
Long-term morphological changes of the blood-aqueous barrier following paracentesis were studied in monkeys. Horseradish peroxidase molecules given intravenously were detected in the intercellular space beyond the tight junction between the nonpigmented ciliary epithelial cells in a monkey 7 days after the operation. The data demonstrated that the breakdown of the blood-aqueous barrier was not functionally repaired 7 days after the operation. Cysts were observed at the most anterior portions of the ciliary processes in monkeys surviving for 14 days to 1 year. These cysts consisted of two layers of both pigmented and nonpigmented epithelial cells. These findings suggest that the breakdown of the blood-aqueous barrier remains not to be repaired for log periods.
Department of Ophthalmology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
T
T
Kubota
Y
Y
Ohnishi
T
T
Ishibashi
S
S
Sugai
D000818:Animals; D000867:Anterior Chamber / Q000601:surgery*; D001082:Aqueous Humor / Q000502:physiology*; D002924:Ciliary Body / Q000648:ultrastructure*; D004848:Epithelium / Q000648:ultrastructure; D006735:Horseradish Peroxidase; D007365:Intercellular Junctions / Q000648:ultrastructure; D008251:Macaca
D006735:Horseradish Peroxidase