Immunoglobulin allotypes in myasthenia gravis patients with a thymoma.
Gm and Km allotypes were examined in 29 myasthenia gravis patients with a thymoma and non-receptor skeletal muscle antibodies. The frequency of the phenotype Gm1,2,3;23;5,21 was significantly higher in the patients than in 292 healthy controls (P less than 0.01). Km allotype frequencies did not differ in patients and controls.
Department of Neurology, University of Bergen, Norway.
N E
NE
Gilhus
J P
JP
Pandey
P I
PI
Gaarder
J A
JA
Aarli
D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001323:Autoantibodies / Q000097:blood / Q000276:immunology; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000276:immunology*; D005260:Female; D006386:Hemagglutination Tests; D006801:Humans; D007126:Immunoglobulin Allotypes / Q000276:immunology*; D007074:Immunoglobulin G / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000276:immunology; D009157:Myasthenia Gravis / Q000150:complications / Q000276:immunology*; D010641:Phenotype; D011950:Receptors, Cholinergic / Q000276:immunology; D013945:Thymoma / Q000150:complications / Q000276:immunology*; D013953:Thymus Neoplasms / Q000150:complications / Q000276:immunology*
D001323:Autoantibodies; D007126:Immunoglobulin Allotypes; D007074:Immunoglobulin G; D011950:Receptors, Cholinergic