Adhesion properties of a neuronal epitope recognized by the monoclonal antibody HNK-1.
A carbohydrate epitope on adhesion proteins of the developing nervous system, and on myelin-associated glycoprotein, is recognized by the monoclonal antibody HNK-1. The HNK-1 epitope bearing proteins and the monoclonal antibody alter, in a dose-dependent manner, the interaction between neurons and neurite-promoting substrate-attached materials released from cultured neural cells.
Riopelle
R J
RJ
McGarry
R C
RC
Roder
J C
JC
D000818:Animals; D000911:Antibodies, Monoclonal; D000954:Antigens, Surface / Q000276:immunology*; D015815:Cell Adhesion Molecules; D002478:Cells, Cultured; D002642:Chick Embryo; D003429:Cross Reactions; D000939:Epitopes / Q000032:analysis*; D005109:Extracellular Matrix / Q000276:immunology; D005727:Ganglia, Spinal / Q000276:immunology; D009185:Myelin Proteins / Q000276:immunology*; D018992:Myelin-Associated Glycoprotein; D009414:Nerve Growth Factors / Q000276:immunology*; D009420:Nervous System / Q000276:immunology*; D013116:Spinal Cord / Q000276:immunology
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface; D015815:Cell Adhesion Molecules; D000939:Epitopes; D009185:Myelin Proteins; D018992:Myelin-Associated Glycoprotein; D009414:Nerve Growth Factors