Visual prognosis in macular retinoblastomas.
Since 1979, we have treated 11 patients who had macular retinoblastomas. Two patients eventually recovered 20/20 visual acuity despite the presence of subretinal fluid in the fovea at the time of diagnosis. The diagnosis was made at 11 and 14 months of age, and follow-up periods were ten and seven years, respectively. One case was sporadic and the other was hereditary. Both patients were treated with external radiation; one patient was also treated with chemotherapy. The lesions regressed markedly after treatment. These cases demonstrate that visual prognosis in macular retinoblastomas is not uniformly poor even when a foveal detachment is present. Visual acuity may be good in some cases, which supports the merits of medical treatment rather than enucleation in selected patients.
Lam
B L
BL
Department of Ophthalmology, University of Iowa Hospitals and Clinics, Iowa City 52242.
Judisch
G F
GF
Sobol
W M
WM
Blodi
C F
CF
D005134:Eye Neoplasms / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D007223:Infant; D008266:Macula Lutea; D011379:Prognosis; D012175:Retinoblastoma / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy; D014785:Vision, Ocular