Ultrasound versus digitally directed prostatic needle biopsy.
During an 8-month period 55 patients with suspected but unproved prostatic carcinoma were entered randomly into a study designed to evaluate the effectiveness of ultrasound-directed transperineal needle biopsy of the prostate. Each patient was biopsied with and without ultrasound assistance; the method used first was determined randomly. Of the 15 patients diagnosed as having adenocarcinoma only 9 were proved by conventional transperineal biopsy, whereas ultrasound-guided biopsy was accurate in all 15 patients (p less than 0.005). Transrectal ultrasound guidance significantly improves the yield of transperineal needle biopsy when it is performed for suspected malignancy.
H T
HT
Liddell
W S
WS
McDougal
D D
DD
Burks
A C
AC
Fleischer
D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology*; D001707:Biopsy, Needle / Q000379:methods*; D006801:Humans; D008297:Male; D011446:Prospective Studies; D011470:Prostatic Hyperplasia / Q000473:pathology; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000473:pathology*; D011897:Random Allocation; D014463:Ultrasonography