Suppression of human alpha-foetoprotein-producing hepatocellular carcinoma growth in nude mice by an anti alpha-foetoprotein antibody-daunorubicin conjugate with a poly-L-glutamic acid derivative as intermediate drug carrier.
Y
Y
Tsukada
K
K
Ohkawa
N
N
Hibi
D000818:Animals; D000906:Antibodies / Q000008:administration & dosage*; D000912:Antibodies, Neoplasm / Q000008:administration & dosage*; D001835:Body Weight; D003602:Cytotoxicity, Immunologic; D003630:Daunorubicin / Q000008:administration & dosage*; D008114:Liver Neoplasms, Experimental / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D008938:Mitosis; D014677:Pharmaceutical Vehicles; D011099:Polyglutamic Acid; D000509:alpha-Fetoproteins / Q000276:immunology* / Q000378:metabolism
D000906:Antibodies; D000912:Antibodies, Neoplasm; D014677:Pharmaceutical Vehicles; D000509:alpha-Fetoproteins; C043914:anti-alpha-fetoprotein antibody-daunomycin conjugate; D011099:Polyglutamic Acid; D003630:Daunorubicin