[Preliminary report on various symptoms of chronic hepatitis treated with radix Astragali and its regulative effect on levels of serum hormone].
67 cases of chronic hepatitis were treated with Radix Astragali. After treatment (2-month course), the clinical improvement rates in 38 cases of the Gan-Yu Pi-Xu type and in 26 cases of the Gan-Shen Yin-Xu type were 92.1% and 88.5% respectively, more effective than that of the control group (P less than 0.05). The regulative effect to the levels of serum hormone was observed in the patients of Gan-Yu Pi-Xu type with this medicine. The results showed that the levels of serum T3, E2 (female) and T (male) were increased after treatment (1.40 +/- 1.38 ng/dl, 129.30 +/- 1.23 pg/ml and 496.24 +/- 1.47 ng/dl respectively) than that before treatment (1.22 +/- 1.49 ng/dl, 104.60 +/- 1.45 pg/ml and 398.17 +/- 1.55 ng/dl respectively, P less than 0.05); however, the level of serum PRL (2.75 +/- 4.46 ng/ml) was lower after treatment than that (3.20 +/- 3.82 ng/ml) before treatment (P less than 0.05). No obvious changes were observed in the levels of serum FSH, LH, TSH, T4; T3U and F after treatment.
Institute of Infectious Diseases, Zhejiang Medical University.
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Liu
D000328:Adult; D002908:Chronic Disease; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004958:Estradiol / Q000097:blood*; D005260:Female; D006509:Hepatitis B / Q000097:blood / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013739:Testosterone / Q000097:blood*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood*
D004365:Drugs, Chinese Herbal; D014284:Triiodothyronine; D013739:Testosterone; D004958:Estradiol; D013972:Thyrotropin; D013974:Thyroxine