[Administration of interferon suppresses clinical and electromyographic signs of myasthenia gravis experimentally transmitted from man to rats].
Intramuscular injection of rat interferon to rats which have been rendered myasthenic after injection of whole blood from patients suffering from myasthenia gravis, suppressed rapidly and almost totally the clinical and electromyographical signs of the disease. Moreover, diseased rats injected with interferon immediately presented an increase in appetite, often accompanied with a rapid and important increase in body weight.
Cueva
J
J
Löshl
D
D
André
P
P
Warter
J M
JM
Poindron
P
P
D000818:Animals; D004195:Disease Models, Animal; D004576:Electromyography; D005247:Feeding Behavior / Q000187:drug effects; D006801:Humans; D007372:Interferons / Q000627:therapeutic use*; D009157:Myasthenia Gravis / Q000503:physiopathology / Q000628:therapy*; D051381:Rats
D007372:Interferons
L'administration d'interféron supprime les signes cliniques et électromyographiques de la myasthenia gravis transmise expérimentalement de l'homme au rat.