[Infection rate with adenivirus 1 to 39 in infants and adults].
To study the infection rate with adenoviruses (Ad) in infants, sera from 75 infants aged 8 to 26 months were tested for neutralizing antibodies against Ad 1 to 39. Antibodies against Ad 1, 2, 5, and 6 were frequently found, against Ad 7 more rarely, whereas one serum reacted with each Ad 3, 4, 18, 31, and 37 and none with all other types. A significant association of positive reactions against several or all of Ad 1, 2, 5, and 6 was observed in neutralization, but not in hemagglutination inhibition, probably due to a subgenus-specific antibody response. The titer of neutralizing antibodies in human gammaglobulin was determined as an estimate for the prevalence of Ad 1 to 39 in the general population.
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Fatz
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Wigand
D000257:Adenoviridae Infections / Q000453:epidemiology*; D000258:Adenovirus Infections, Human / Q000453:epidemiology* / Q000382:microbiology; D000260:Adenoviruses, Human / Q000145:classification / Q000276:immunology*; D000328:Adult; D000367:Age Factors; D000914:Antibodies, Viral / Q000032:analysis*; D002675:Child, Preschool; D005860:Germany, West; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007223:Infant; D009500:Neutralization Tests; D012703:Serotyping; D005719:gamma-Globulins / Q000032:analysis
D000914:Antibodies, Viral; D005719:gamma-Globulins
Die Durchseuchung mit Adenovirus 1 bis 39 im Kleinkindesalter und bei Erwachsenen.