[Rare malignant tumors of the ovaries in adolescents--clinical aspects in deciding therapeutic aggressiveness].
4 patients below the age of 20 years have been treated for a malignant tumor of the ovary during the period November 1, 1984 until April 30, 1988. Dysgerminoma was the diagnosis in two cases, as the third patient suffered from a bilateral malignant teratoma. Burkitt's Lymphoma involved both ovaries primarily in an 17-year-old girl. Retrospectively we analyzed diagnosis, therapy and clinical course of these young patients. Regarding the different histological types of the tumors that have been found we discuss critically current recommendations in therapeutic managements referring chemotherapy and/or radiotherapy. Defined conditions provided surgical treatment, that preserves fertility in early stages of malignant germ cell tumors of adolescent women, may be justified, especially for dysgerminomas. A real benefit relate to survival and quality of life by using chemotherapeutic agents can only be expected, if all prognostic factors are regarded.
Frauenklinik der Städtischen Kliniken Offenbach.
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D000293:Adolescent; D000328:Adult; D002051:Burkitt Lymphoma / Q000601:surgery*; D004407:Dysgerminoma / Q000601:surgery*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D009378:Neoplasms, Multiple Primary / Q000601:surgery*; D010051:Ovarian Neoplasms / Q000601:surgery*; D010052:Ovariectomy; D012086:Reoperation; D013724:Teratoma / Q000601:surgery*
Seltene maligne Tumoren der Ovarien bei Jugendlichen--klinische Aspekte zur Wahl der therapeutischen Aggressivität.