Immunomodulators and allergy.
The role played by immunomodulation in allergy is critically reviewed. The prospective mechanisms of immunomodulation, specifically including those showing relation with allergic phenomena, are taken into consideration, examining the main interfering factors. Type I, IgE-mediated immunoreaction, in its two aspects, IgE synthesis and mediator's release, is analyzed, bearing in mind some agents involved or affecting these processes, mimicking immunomodulation. Other agents, such as Corynebacterium granulosum derivatives and glucocorticoids have been also appraised, to highlight their action in this connection.
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D000119:Acetylmuramyl-Alanyl-Isoglutamine / Q000276:immunology; D000818:Animals; D017302:Annexins; D000918:Antibody Specificity; D002121:Calcium Channel Blockers / Q000494:pharmacology; D002147:Calmodulin / Q000037:antagonists & inhibitors; D002634:Chemotaxis, Leukocyte / Q000187:drug effects; D002927:Cimetidine / Q000494:pharmacology; D002940:Circadian Rhythm; D003352:Corynebacterium / Q000276:immunology; D004205:Cromolyn Sodium / Q000494:pharmacology; D004334:Drug Administration Schedule; D000939:Epitopes / Q000276:immunology; D006023:Glycoproteins / Q000276:immunology; D006680:HLA Antigens / Q000276:immunology; D006632:Histamine / Q000276:immunology; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology*; D007107:Immune System; D007073:Immunoglobulin E / Q000276:immunology; D007141:Immunoglobulin Fc Fragments / Q000276:immunology; D007167:Immunotherapy; D007372:Interferons / Q000627:therapeutic use; D007694:Killer Cells, Natural / Q000276:immunology; D007975:Leukotriene B4 / Q000494:pharmacology; D007978:Levamisole / Q000627:therapeutic use; D008264:Macrophages / Q000276:immunology; D011453:Prostaglandins / Q000494:pharmacology; D011899:Ranitidine / Q000494:pharmacology; D011951:Receptors, Complement / Q000378:metabolism; D017463:Receptors, Complement 3b; D013256:Steroids / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
D017302:Annexins; D002121:Calcium Channel Blockers; D002147:Calmodulin; D000939:Epitopes; D006023:Glycoproteins; D006680:HLA Antigens; D007141:Immunoglobulin Fc Fragments; D011453:Prostaglandins; D011951:Receptors, Complement; D017463:Receptors, Complement 3b; D013256:Steroids; D007975:Leukotriene B4; D007978:Levamisole; D007073:Immunoglobulin E; D000119:Acetylmuramyl-Alanyl-Isoglutamine; D002927:Cimetidine; D006632:Histamine; D011899:Ranitidine; D007372:Interferons; D004205:Cromolyn Sodium