Neurotrophic factors.
In addition to nerve growth factor (NGF), many proteins present in soluble tissue extracts and in the extracellular matrix influence the survival and development of cultured neurons. The structure, synthesis, and mechanism of action of NGF as a neurotrophic factor are considered along with the experiments on the new putative trophic molecules.
Thoenen
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Edgar
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D000818:Animals; D001483:Base Sequence; D002417:Cattle; D002470:Cell Survival; D002478:Cells, Cultured; D002642:Chick Embryo; D002645:Chickens; D000242:Cyclic AMP / Q000502:physiology; D004247:DNA / Q000235:genetics; D005109:Extracellular Matrix / Q000502:physiology; D006801:Humans; D007473:Ion Channels / Q000502:physiology; D008297:Male; D051379:Mice; D008970:Molecular Weight; D009206:Myocardium / Q000166:cytology; D009414:Nerve Growth Factors / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology*; D009474:Neurons / Q000502:physiology; D011498:Protein Precursors / Q000235:genetics; D012333:RNA, Messenger / Q000378:metabolism; D051381:Rats; D011956:Receptors, Cell Surface / Q000502:physiology; D017475:Receptors, Nerve Growth Factor; D013564:Sympathetic Nervous System / Q000166:cytology
D007473:Ion Channels; D009414:Nerve Growth Factors; D011498:Protein Precursors; D012333:RNA, Messenger; D011956:Receptors, Cell Surface; D017475:Receptors, Nerve Growth Factor; C044242:nerve growth factor, beta subunit precursor; D004247:DNA; D000242:Cyclic AMP