[Effects of aminoglycosides on T and B lymphocyte populations: in vitro study].
The authors tested the influence of gentamycin, spectinomycin,and dihydrostreptomycin on the formation of EAChu and EAT rosettes and they have found a significant reduction of the percentage of EAChu rosettes. Probably this reduction is due to an interaction with the receptor sites for the Complement of B lymphocytes and/or an in vitro denaturation Complement.
Nubile
G
G
Tresca
E
E
Di Profio
E
E
Ridolfi
D
D
Di Biagio
A
A
D000328:Adult; D001402:B-Lymphocytes / Q000187:drug effects* / Q000276:immunology; D004096:Dihydrostreptomycin Sulfate / Q000494:pharmacology*; D005260:Female; D005839:Gentamicins / Q000494:pharmacology*; D006801:Humans; D008297:Male; D012397:Rosette Formation; D000198:Spectinomycin / Q000494:pharmacology*; D013601:T-Lymphocytes / Q000187:drug effects* / Q000276:immunology
D005839:Gentamicins; D000198:Spectinomycin; D004096:Dihydrostreptomycin Sulfate
Effetti degli aminoglicosidi sulle popolazioni linfocitarie T e B: studio "in vitro".