[New developments in the area of markers in diagnosis and monitoring of ovarian cancer].
The diagnostic and prognostic prediction of ovarian carcinoma can be substantially improved by combining serological markers synchronized with radiological and morphological methods. The validity of the following markers was investigated in a prospective trial between 1977 and 1983: CEA, TPA, SP-1, SP-3, alpha-1-antitrypsin, alpha-2-macroglobulin, c-reactive protein. The results were correlated with those of the CA 12-5 determination. Pre-operatively, ovarian carcinoma was indicated by CA 12-5 (93.7%), sialyl transferase (65.6%), TPA (53.1%), CEA (28.1%). These markers would appear suitable to control the clinical course.
Kreienberg
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Melchert
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D000951:Antigens, Neoplasm / Q000032:analysis*; D015295:Antigens, Tumor-Associated, Carbohydrate; D002097:C-Reactive Protein / Q000032:analysis; D002272:Carcinoembryonic Antigen / Q000032:analysis; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000276:immunology; D010455:Peptides / Q000032:analysis; D011257:Pregnancy Proteins / Q000032:analysis; D011268:Pregnancy-Specific beta 1-Glycoproteins / Q000032:analysis; D019396:Tissue Polypeptide Antigen; D000515:alpha 1-Antitrypsin / Q000032:analysis; D000509:alpha-Fetoproteins / Q000032:analysis; D000511:alpha-Macroglobulins / Q000032:analysis
D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate; D002272:Carcinoembryonic Antigen; D010455:Peptides; D011257:Pregnancy Proteins; D011268:Pregnancy-Specific beta 1-Glycoproteins; D019396:Tissue Polypeptide Antigen; D000515:alpha 1-Antitrypsin; D000509:alpha-Fetoproteins; D000511:alpha-Macroglobulins; C017589:ovarian tumor associated antigen; D002097:C-Reactive Protein
Neuentwicklungen auf dem Gebiet der Marker zur Diagnostik und Uberwachung des Ovarialkarzinoms.