Hydrodynamically balanced systems as sustained release dosage forms for propranolol hydrochloride.
Sustained release hydrodynamically balanced capsules (HBS) of propranolol.HCl have been prepared and evaluated in vitro. Data to support the mechanism of drug release from the HBS capsule are also presented. Floating behaviour of the HBS capsule has also been seen in vivo with the help of endoscopy.
Khattar
D
D
Department of Pharmaceutics, Hamdard College of Pharmacy, New Dehli, India.
Ahuja
A
A
Khar
R K
RK
D000328:Adult; D002214:Capsules; D002626:Chemistry, Pharmaceutical; D003102:Colloids; D003692:Delayed-Action Preparations; D005773:Gastroscopy; D006801:Humans; D008297:Male; D011433:Propranolol / Q000008:administration & dosage* / Q000032:analysis; D012995:Solubility
D002214:Capsules; D003102:Colloids; D003692:Delayed-Action Preparations; D011433:Propranolol