[Latent vitamin K deficiency in breast-fed infants].
Quick test, coagulation activity of vitamin K-dependent clotting factors, factor II activity by ecarin, levels of factor II immunoreactive antigen and acarboxyprothrombin were examined in two groups of infants, breast-fed and bottle-fed at the ages of one month and 3 months. None of them received vitamin K at birth and later. Acarboxyprothrombin could be demonstrated in about 14% at the both age of life of breast-fed children, but not in the groups of bottle-fed infants. The activity of coagulation factors was significantly lower in the acarboxyprothrombin-positive group compared to the acarboxyprothrombin-negative group. In none of the infants manifest bleeding was observed. No difference in the activities of factors could be detected in the acarboxyprothrombin-negative groups of breast- and bottle-fed children. These data suggest a frequent latent deficiency of vitamin K in breast-fed infants.
Pest Megyei Semmelweis Kórház, Gyermekosztály.
B
B
Goldschmidt
L
L
Benedek
Z
Z
Golán
M
M
Bukovszky
I
I
Markó
D001942:Breast Feeding; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D007020:Hypoprothrombinemias / Q000097:blood / Q000175:diagnosis; D007231:Infant, Newborn; D011516:Prothrombin / Q000032:analysis; D011517:Prothrombin Time; D014813:Vitamin K Deficiency / Q000097:blood / Q000175:diagnosis* / Q000453:epidemiology
D011516:Prothrombin
Latens K-vitamin-hiány anyatejjel táplált csecsemökben.