Apolipoprotein E: receptor binding properties.
The E apoprotein plays a central role in lipoprotein metabolism. It is a key protein determinant responsible for the recognition of lipoproteins by specific lipoprotein receptors. Structure-function studies are providing insights into the normal function of this apoprotein in cholesterol homeostasis and into the clinical abnormalities resulting from the occurrence of specific mutants.
K H
KH
Weisgraber
T L
TL
Innerarity
S C
SC
Rall
R W
RW
Mahley
D000911:Antibodies, Monoclonal; D001057:Apolipoproteins E / Q000145:classification / Q000276:immunology / Q000378:metabolism*; D001665:Binding Sites; D001667:Binding, Competitive; D000939:Epitopes; D006801:Humans; D006952:Hyperlipoproteinemia Type III / Q000378:metabolism*; D007526:Isoelectric Point; D010446:Peptide Fragments / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000378:metabolism*; D011973:Receptors, LDL / Q000378:metabolism; D018110:Receptors, Lipoprotein; D013329:Structure-Activity Relationship
D000911:Antibodies, Monoclonal; D001057:Apolipoproteins E; D000939:Epitopes; D010446:Peptide Fragments; D011956:Receptors, Cell Surface; D011973:Receptors, LDL; D018110:Receptors, Lipoprotein; C032531:apolipoprotein B,E receptor