51Cr-bleomycin in the diagnosis of tumours of the chest.
51Cr-bleomycin was used for the scintigraphic diagnosis of primary and secondary tumours of the thorax. The study was based on observations in 104 patients. The scintigraphy was performed using a gamma camera coupled to an on-line computer. Active lesions were scored using a semiquantitative scale of scores 0 to 5. Images were subdivided into 222 regions considered. In 72 of these, the presence of disease was diagnosed (64 malignant, 8 non-malignant) and 150 regions were classified as free from disease. At the decision threshold of score 2, over-all sensitivity and specificity of the scintigraphic detection of malignant tumours amounted to 97 and 79%, respectively. Inflammatory changes displayed some detectable accumulation of 51Cr-bleomycin but scores attributed to these lesions did not exceed the value of 2.
Brykalski
D
D
Liniecki
J
J
Dobek
J
J
Pertyński
T
T
Fajndt
S
S
Studniarek
M
M
Durski
K
K
Mussur
M
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D001761:Bleomycin; D002648:Child; D002675:Child, Preschool; D002860:Chromium Radioisotopes; D005069:Evaluation Studies as Topic; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D011859:Radiography; D011877:Radionuclide Imaging; D013899:Thoracic Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary
D002860:Chromium Radioisotopes; D001761:Bleomycin