[Biological features of the skin of the pika, Ochotona rufescens rufescens--concentration of histamine in the skin].
The quantity of histamine and the number of mast cells in the skin of the pika were measured and compared with rabbits, guinea pigs and rats. The ranking of regional histamine levels in the skin of the pika was: perianal region greater than abdomen greater than interscapular region = back greater than lumbus greater than head greater than auricle, and the average value of the 7 regions was 22.6 micrograms/g. The level of histamine in the 6 regions, except the auricle, was 2-5 times that of rabbits and guinea pigs. In the auricle of each of the 4 kinds of animal (pika, rabbit, guinea pig and rat), the levels were almost identical. With respect to histamine levels, those in the pika resembled those in rats. The number of mast cells in the skin of the pika was less than in rats, and was greater than that in rabbits and guinea pigs. The average value was 9.9/mm2.
Department of Veterinary Hygiene, College of Agriculture and Veterinary Medicine, Nihon University, Kanagawa, Japan.
Y
Y
Kodama
T
T
Sakai
K
K
Naitou
S
S
Horiuchi
D000818:Animals; D002452:Cell Count; D006168:Guinea Pigs; D006632:Histamine / Q000032:analysis*; D008407:Mast Cells; D011817:Rabbits / Q000378:metabolism*; D051381:Rats; D012867:Skin / Q000032:analysis* / Q000166:cytology
D006632:Histamine