[Natural killers and their physiological importance].
Natural killer cells (NK cells) are a distinct subset of mononuclear cells that rapidly kill certain tumor cell lines and even normal cells without a prior sensibilization to the targets. Probably, NK cells are the "first line of defence" in the body against foreign agents. A hypothesis about the role of NK cells in the natural antitumor resistance and in the control of cell proliferation and differentiation has recently been confirmed.
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Malygin
D000818:Animals; D000954:Antigens, Surface / Q000276:immunology; D001327:Autoimmune Diseases / Q000276:immunology; D001853:Bone Marrow / Q000276:immunology; D002454:Cell Differentiation / Q000187:drug effects; D002455:Cell Division; D002999:Clone Cells / Q000276:immunology; D003602:Cytotoxicity, Immunologic; D005347:Fibroblasts / Q000276:immunology; D006801:Humans; D007113:Immunity, Innate; D007114:Immunization; D007125:Immunogenetics; D007372:Interferons / Q000494:pharmacology; D007694:Killer Cells, Natural / Q000187:drug effects / Q000276:immunology / Q000502:physiology*; D051379:Mice; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000276:immunology; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology
D000954:Antigens, Surface; D007372:Interferons
Natural'nye killery i ikh fiziologicheskoe znachenie.