[Assessment of cisplatin in concurrent use with radiotherapy in esophageal carcinoma--joint research among nationwide multi-facilities, primary results. Research Committee for Radiation and Cisplatin Treatment of Esophageal Carcinoma].
The effect of cisplatin in concurrent use with radiotherapy for esophageal carcinoma has been assessed as a theme of joint research among nationwide 40 facilities for 18 months from October, 1985, to March, 1987. As the subjects, non-operative cases, recurrent cases and metastatic cases diagnosed as esophageal carcinoma were enrolled. Regimens in 4 kinds were used for treatment and CDDP was used concurrently with radiotherapy in all the regimens. The results of classifying and totalizing the effects in 73 cases, of whom the local effects were analyzed, turned out to be: CR-25 cases, CR rate being 34.2% and PR-33 cases, the effective rate being 79.5%. As a result of aggregating the effects by major axis of X-ray image, CR and effective rates were found as 60 and 90% in the cases with the axes less than 5 cm; 36 and 79% in the cases with axes more than 5 cm and less than 10 cm; and 19 and 76% in the cases with the axes more than 10 cm, all respectively.
Naruto Hospital.
T
T
Ishikawa
G
G
Irie
H
H
Asakawa
M
M
Ikeda
T
T
Dokiya
K
K
Morita
T
T
Inoue
K
K
Masuda
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D011379:Prognosis; D011879:Radiotherapy Dosage; D012074:Remission Induction
D002945:Cisplatin