[Clinical study on serum immunosuppressive factors in gastric cancer patients--with special reference to preoperative IAP values and the influence of surgical stress].
Serum IAP values were measured preoperatively in 83 gastric cancer patients. The levels were significantly higher in cases of total, stage III and IV, n (+) and non-curative resection than in normal subjects, stage I, n (-) and curative resection. There was a significant correlation between IAP on the one hand, and IgG FcR (+) T cell, alpha 2-globulin and CEA on the other. OK-432 was serially administered pre- and postoperatively (A) and only postoperatively (B). IAP was examined at one, two and four weeks postoperatively, and the findings were compared. It was increased markedly at one week and was slightly reduced at two and four weeks. These changes in IAP showed no significant differences between groups A and B.
Yokoyama
Y
Y
Saji
S
S
Niwa
H
H
Takao
H
H
Kida
H
H
Umemoto
T
T
Kawata
R
R
Sakata
K
K
Tanaka
S
S
D002272:Carcinoembryonic Antigen / Q000032:analysis; D005293:Ferritins / Q000097:blood; D005743:Gastrectomy; D006801:Humans; D007141:Immunoglobulin Fc Fragments / Q000032:analysis; D008213:Lymphocyte Activation; D009363:Neoplasm Proteins / Q000032:analysis*; D010844:Picibanil / Q000627:therapeutic use; D012016:Reference Values; D013274:Stomach Neoplasms / Q000097:blood / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology; D000511:alpha-Macroglobulins / Q000032:analysis
D002272:Carcinoembryonic Antigen; D007141:Immunoglobulin Fc Fragments; D009363:Neoplasm Proteins; D000511:alpha-Macroglobulins; C030193:immunosuppressive acidic protein; D010844:Picibanil; D005293:Ferritins