Antigenic differences between virulent and avirulent strains of Semliki Forest viruses detected with monoclonal antibodies. Brief report.
Eleven monoclonal antibodies (MAs) reacted strongly in an enzyme immunoassay with virulent Semliki Forest virus (SFV) replicating in L cell monolayers. Three MAs showed a considerably diminished reaction with an avirulent strain of SFV both in enzyme immunoassays and plaque reduction tests.
Boere
W A
WA
Harmsen
M
M
Kraaijeveld
C A
CA
Snippe
H
H
D000595:Amino Acid Sequence; D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000956:Antigens, Viral / Q000032:analysis*; D000939:Epitopes / Q000032:analysis; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009500:Neutralization Tests; D012672:Semliki forest virus / Q000276:immunology* / Q000472:pathogenicity; D014774:Virulence
D000911:Antibodies, Monoclonal; D000956:Antigens, Viral; D000939:Epitopes