Determination of 2,6-dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethylester in nifedipine by derivative UV-spectrophotometry in bulk material and pharmaceutical forms.
A method for the determination of 2,6-dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethylester in nifedipine (bulk material and pharmaceutical formulations) by second-derivative ultraviolet spectrophotometry is described. The procedure is simple and rapid and gives accurate and precise results.
Dipartimento di Chimica, Università dell'Aquila, Italy.
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G
Carlucci
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A
Colanzi
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Mazzeo
D004095:Dihydropyridines / Q000032:analysis*; D007202:Indicators and Reagents; D009543:Nifedipine / Q000032:analysis*; D012996:Solutions; D013056:Spectrophotometry, Ultraviolet; D013607:Tablets
D004095:Dihydropyridines; D007202:Indicators and Reagents; D012996:Solutions; D013607:Tablets; C065818:2,6-dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester; D009543:Nifedipine