[The context analysis of polynucleotide sequences. II. Inverted repeats and complementary palindromes in RNA-polymerase genes].
A new approach to the reconstruction of the RNA secondary structure is suggested on the basis of the method of contextual analysis of polynucleotide sequences. The coding gene regions of beta-, beta'-, sigma-subunits of E. coli RNA polymerase and of phage T7 RNA polymerase were analysed. The clusters of non-random inverted repeats were found in all these genes. The mRNA coded by them can be folded into compact secondary structures. The latter are formed by quite long helices with a few cases of mispairing.
A A
AA
Zharkikh
V V
VV
Solov'ev
N A
NA
Kolchanov
D007446:Chromosome Inversion; D004269:DNA, Bacterial / Q000235:genetics; D012321:DNA-Directed RNA Polymerases / Q000235:genetics*; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics*; D005798:Genes, Bacterial; D005816:Genetic Complementation Test; D008957:Models, Genetic; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D012329:RNA, Bacterial / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics; D012091:Repetitive Sequences, Nucleic Acid
D004269:DNA, Bacterial; D012329:RNA, Bacterial; D012333:RNA, Messenger; D012321:DNA-Directed RNA Polymerases
Kontekstnyĭ analiz polinukleotidnykh posledovatel'nosteĭ. II. Invertirovannye povtory i komplementarnye palindromy v genakh RNK-polimeraz.