Vitamin K treatment of sweet clover poisoning in calves.
Dicumarol poisoning was reproduced by feeding naturally spoiled, sweet clover hay, which contained a minimum of 90 ppm dicumarol. Vitamin K1 administered IM was effective in treating the disease at dosages of 1.1, 2.2, and 3.3 mg/kg of body weight. Vitamin K3 treatment by various routes and dosages was ineffective.
Alstad
A D
AD
Casper
H H
HH
Johnson
L J
LJ
D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000139:chemically induced / Q000188:drug therapy / Q000209:etiology*; D002986:Clinical Trials as Topic; D001728:Dicumarol / Q000506:poisoning*; D007020:Hypoprothrombinemias / Q000139:chemically induced / Q000662:veterinary*; D010939:Plant Poisoning / Q000188:drug therapy / Q000662:veterinary*; D011517:Prothrombin Time / Q000662:veterinary; D014812:Vitamin K / Q000008:administration & dosage / Q000627:therapeutic use; D010837:Vitamin K 1 / Q000008:administration & dosage / Q000627:therapeutic use*
D014812:Vitamin K; D001728:Dicumarol; D010837:Vitamin K 1