[Cytoplasmic and nuclear receptors of estradiol in the hypothalamus and cerebral cortex of female rats in the neonatal period].
The content of estradiol receptors (E2) was studied in the cytoplasmic and nuclear fractions of the female rat hypothalamus and cortex during neonatal development. In the cytosol the E2-binding proteins, having a high capacity, include both true estradiol receptors and proteins identical with alpha-fetoprotein. True E2 receptors were found in the nuclear fraction: their concentration underwent almost no changes in hypothalamus and decreased from the 1st to the 5th day of postnatal development in cortex.
Shishkina
I V
IV
Ozol'
L Iu
LIu
Babichev
V N
VN
D000818:Animals; D000831:Animals, Newborn; D002467:Cell Nucleus / Q000032:analysis; D002540:Cerebral Cortex / Q000032:analysis*; D003593:Cytoplasm / Q000032:analysis; D003600:Cytosol / Q000032:analysis; D004958:Estradiol / Q000378:metabolism*; D005260:Female; D007031:Hypothalamus / Q000032:analysis*; D007986:Luteinizing Hormone / Q000097:blood; D051381:Rats; D011959:Receptors, Estradiol / Q000032:analysis*; D011960:Receptors, Estrogen / Q000032:analysis*; D012741:Sexual Maturation; D000509:alpha-Fetoproteins / Q000378:metabolism
D011959:Receptors, Estradiol; D011960:Receptors, Estrogen; D000509:alpha-Fetoproteins; D004958:Estradiol; D007986:Luteinizing Hormone
Tsitoplazmaticheskie i iadernye retseptory éstradiola v gipotalamuse i kore golovnogo mozga samok krys v neonatal'nom periode.