Chemotaxis of macrophage in inflammation.
Our particular attention in this article was given to natural mediators for macrophages isolated from the sites of tissue injury. A number of chemotactic factors, which may satisfy many criteria making them acceptable as inflammatory leucocyte chemotactic factors, has been separated. Among them, our laboratory has isolated three macrophage (monocyte) chemotactic factors (MCF-a, -b and -c). Their purification, characterization and functional specificity are discussed.
Hayashi
H
H
Yoshimura
T
T
Chen
J Y
JY
D000818:Animals; D002630:Chemotactic Factors / Q000276:immunology / Q000302:isolation & purification*; D002633:Chemotaxis; D003182:Complement C5 / Q000276:immunology; D003872:Dermatitis / Q000276:immunology; D000939:Epitopes / Q000276:immunology; D006168:Guinea Pigs; D000949:Histocompatibility Antigens Class II / Q000276:immunology; D007074:Immunoglobulin G / Q000276:immunology; D007249:Inflammation / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology; D008264:Macrophages / Q000276:immunology*; D051379:Mice; D009000:Monocytes / Q000276:immunology; D051381:Rats
D002630:Chemotactic Factors; D003182:Complement C5; D000939:Epitopes; D000949:Histocompatibility Antigens Class II; D007074:Immunoglobulin G