Metastasizing pineal germinoma. A case report and review.
A patient with biopsy-proven pineal germinoma was treated successfully by craniospinal irradiation. Lung and hilar node metastases developed 22 months after therapy. These were subtotally resected and further cis-platinum, vinblastine and bleomycin chemotherapy given with control 8 months later. Twenty cases of metastases from pineal tumours are documented. The role of chemotherapy as adjuvant therapy, and in recurrent and metastatic disease is reviewed.
C V
CV
Levin
G S
GS
Rutherfoord
D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage; D001932:Brain Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D008297:Male; D010871:Pinealoma / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D014747:Vinblastine / Q000008:administration & dosage
D001761:Bleomycin; D014747:Vinblastine; D002945:Cisplatin