Primary germinoma of the posterior fossa with CSF and extracranial metastases.
We describe the case of a 1-year-old boy presenting clinically and radiologically with a haematoma occurring in the cerebellum. Histological examination revealed a germ cell tumour with a pure germinomatous component. The patient subsequently succumbed with extensive tumour metastases in the spinal cord and the subcutaneous tissues of the scalp. This represents the first comprehensive documented report of a germinoma arising in the posterior fossa.
Department of Anatomical and Cellular Pathology, Chinese University of Hong Kong.
H K
HK
Ng
W S
WS
Poon
D002528:Cerebellar Neoplasms / Q000134:cerebrospinal fluid / Q000473:pathology* / Q000601:surgery; D002543:Cerebral Hemorrhage / Q000473:pathology; D003388:Cranial Fossa, Posterior; D004407:Dysgerminoma / Q000134:cerebrospinal fluid / Q000556:secondary* / Q000601:surgery; D006406:Hematoma / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D012535:Scalp; D012878:Skin Neoplasms / Q000556:secondary; D013120:Spinal Cord Neoplasms / Q000556:secondary