[Recent findings on the molecular biology of Plasmodium antigens].
The cloning of several genes coding for Plasmodium antigens has allowed to determine the nucleotide sequence of these genes and to deduce the amino acid sequence of the antigens. In this review we summarize the first results concerning the CSP of P. knowlesi and P. falciparum as well as several antigens from the asexual erythrocytic stages. These antigens show the unique feature to contain one or several antigenic determinants composed of repetitive units.
Jaureguiberry
G
G
Mercereau-Puijalon
O
O
D000595:Amino Acid Sequence; D000818:Animals; D000953:Antigens, Protozoan / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis; D003001:Cloning, Molecular; D000939:Epitopes / Q000032:analysis*; D010961:Plasmodium / Q000235:genetics / Q000276:immunology*; D010963:Plasmodium falciparum / Q000235:genetics / Q000276:immunology; D015800:Protozoan Proteins
D000953:Antigens, Protozoan; D000954:Antigens, Surface; D000939:Epitopes; C044243:FIRA protein, Plasmodium falciparum; D015800:Protozoan Proteins; C041595:circumsporozoite protein, Protozoan
Données récentes sur la biologie moléculaire des antigènes de Plasmodium.