Glucose tolerance test and insulin levels in children with transfusion-dependent thalassaemia.
Blood glucose and serum immunoreactive insulin levels were measured following an oral glucose load in 20 unrelated children with multiple transfused thalassaemia. Results suggest that even though overt diabetes and glucose intolerance are uncommon before the age of 13 years, the presence of insulin resistance is evident, especially in those who have been splenectomized.
Lee
B W
BW
Tan
S H
SH
Lee
W K
WK
Yap
H K
HK
Aw
S E
SE
Wong
H B
HB
D000293:Adolescent; D001786:Blood Glucose / Q000032:analysis; D001803:Blood Transfusion; D002648:Child; D002675:Child, Preschool; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D007223:Infant; D007328:Insulin / Q000097:blood* / Q000276:immunology; D008297:Male; D013156:Splenectomy; D013789:Thalassemia / Q000097:blood* / Q000628:therapy
D001786:Blood Glucose; D007328:Insulin