Serotonin content of foods: effect on urinary excretion of 5-hydroxyindoleacetic acid.
Using a highly specific radioenzymatic assay we determined the serotonin concentration in 80 types of foods. The following fruits had a high serotonin concentration (mean +/- SEM) expressed in micrograms/g weight: plantain 30.3 +/- 7.5; pineapple 17.0 +/- 5.1; banana 15.0 +/- 2.4; Kiwi fruit 5.8 +/- 0.9; plums 4.7 +/- 0.8; and tomatoes 3.2 +/- 0.6. Only nuts in the walnut or hickory family had a high serotonin concentration expressed in micrograms/g weight; butternuts 398 +/- 90; black walnuts 304 +/- 46; English walnuts 87 +/- 20; shagbark hickory nuts 143 +/- 23; mockernut hickory nuts 67 +/- 13; pecans 29 +/- 4; and sweet pignuts 25 +/- 8. Ingestion of these fruits and nuts resulted in an increase in urinary 5-hydroxyindoleacetic acid excretion with no change in platelet serotonin concentration. The above foods should not be eaten while a urine is being collected for 5-hydroxyindoleacetic acid analysis.
J M
JM
Feldman
E M
EM
Lee
D000328:Adult; D001792:Blood Platelets / Q000378:metabolism; D002855:Chromatography, Thin Layer; D005260:Female; D005504:Food Analysis; D005638:Fruit / Q000032:analysis; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000652:urine*; D008297:Male; D008875:Middle Aged; D009754:Nuts / Q000032:analysis; D012701:Serotonin / Q000032:analysis* / Q000097:blood / Q000652:urine; D014675:Vegetables / Q000032:analysis
D012701:Serotonin; D006897:Hydroxyindoleacetic Acid