[Modulation of the induction of interferon formation by calcium chloride].
The results of the study confirm earlier reports on the stimulating effect of calcium ions on production of interferon induced by poly(I) X poly(C) and on translation of messenger RNA for interferon. Neutralization of the inhibiting activity of interferon production suppressor present in the cytoplasm of normal cells has first been demonstrated which broadens our concepts on the mechanism of action of calcium ions.
T G
TG
Orlova
A I
AI
Bokhon'ko
T V
TV
Mamontova
A I
AI
Kognovitskaia
D000818:Animals; D002122:Calcium Chloride / Q000494:pharmacology*; D003600:Cytosol / Q000187:drug effects / Q000276:immunology; D003637:DEAE-Dextran / Q000494:pharmacology; D007372:Interferons / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D007739:L Cells / Q000187:drug effects / Q000276:immunology; D051379:Mice; D011070:Poly I-C / Q000494:pharmacology; D013268:Stimulation, Chemical; D013997:Time Factors
D007372:Interferons; D003637:DEAE-Dextran; D002122:Calcium Chloride; D011070:Poly I-C
Moduliatsiia induktsii interferonoobrazovaniia khloridom kal'tsiia.