Melanocyte metabolites in the urine of people of different skin colour.
The urinary excretion of 2 melanocyte metabolites was studied in normal people of different skin type. The sulphur-free indole derivative 6-hydroxy-5-methoxyindole-2-carboxylic acid was excreted in larger quantities by people with genetically dark skin, whereas the excretion of 5-S-cysteinyldopa was not related to pigment type. No correlation between 5-S-cysteinyldopa and 6-hydroxy-5-methoxyindole-2-carboxylic acid excretion emerged.
Wirestrand
L E
LE
Hansson
C
C
Rosengren
E
E
Rorsman
H
H
D000328:Adult; D044383:Black People; D003548:Cysteinyldopa / Q000652:urine*; D004295:Dihydroxyphenylalanine / Q000031:analogs & derivatives*; D005260:Female; D006801:Humans; D007211:Indoles / Q000652:urine*; D008297:Male; D008543:Melanins / Q000378:metabolism; D008544:Melanocytes / Q000378:metabolism*; D012880:Skin Pigmentation; D044465:White People
D007211:Indoles; D008543:Melanins; D003548:Cysteinyldopa; C017408:6-hydroxy-5-methoxy-2-indolylcarboxylic acid; D004295:Dihydroxyphenylalanine