Detection of combined ABH and Lewis glycosphingolipids in sera of H-deficient donors.
The sera of H-normal, H-weak and H-deficient individuals transferred the same amounts of ABH and Lewis antigens to lymphocytes in culture, confirming that the circulating ABH and Lewis antigens detected by lymphocytotoxicity are independent of the H-h system. These antigens were, as expected, under the control of the secretor and Lewis systems in the same way as exocrine secretions. These results suggest that both circulating ABH and Lewis glycosphingolipids and exocrine ABH and Lewis glycoproteins can be synthesized by the same tissues.
Bernoco
M
M
Danilovs
J
J
Terasaki
P I
PI
Cartron
J P
JP
Mollicone
R
R
Le Pendu
J
J
Oriol
R
R
D000017:ABO Blood-Group System / Q000032:analysis / Q000235:genetics / Q000276:immunology*; D003601:Cytotoxicity Tests, Immunologic; D000939:Epitopes; D006028:Glycosphingolipids / Q000097:blood / Q000276:immunology*; D006801:Humans; D007983:Lewis Blood Group Antigens / Q000032:analysis / Q000235:genetics / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology
D000017:ABO Blood-Group System; D000939:Epitopes; D006028:Glycosphingolipids; D007983:Lewis Blood Group Antigens