Evidence for possible increase of sodium channel open time and involvement of Na/Ca exchange by a new positive inotropic drug: OPC-8212.
D A
DA
Lathrop
A
A
Schwartz
D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D002118:Calcium / Q000378:metabolism*; D002316:Cardiotonic Agents / Q000494:pharmacology*; D004594:Electrophysiology; D006168:Guinea Pigs; D066298:In Vitro Techniques; D007473:Ion Channels / Q000187:drug effects*; D008012:Lidocaine / Q000494:pharmacology; D009206:Myocardium / Q000378:metabolism; D011690:Purkinje Fibers / Q000187:drug effects; D011719:Pyrazines; D011804:Quinolines / Q000494:pharmacology*; D012964:Sodium / Q000378:metabolism*; D014702:Veratrine / Q000494:pharmacology
D002316:Cardiotonic Agents; D007473:Ion Channels; D011719:Pyrazines; D011804:Quinolines; C041667:vesnarinone; D008012:Lidocaine; D012964:Sodium; D014702:Veratrine; D002118:Calcium