Response of early disseminated Herpes simplex to acycloguanosine: a case report.
Acycloguanosine, an anti-viral agent with few side effects and good activity in vitro against Herpes simplex, has not produced a consistently high cure rate in clinical practice (1). This may in part be related to delayed initiation of therapy (2). We describe a case of disseminated Herpes simplex (DHS) in an immunocompromised child (which is normally associated with a fatal outcome) who responded rapidly and completely to treatment with acycloguanosine.
M E
ME
Ellis
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MK
Mackenjee
D000212:Acyclovir / Q000627:therapeutic use*; D005260:Female; D006561:Herpes Simplex / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D007223:Infant
D000212:Acyclovir