Failure to detect anti-MAG antibodies by RIA in CSF of patients with multiple sclerosis.
Using a sensitive double-antibody radioimmunoassay (RIA) we measured IgG antibodies to the myelin-associated glycoprotein (MAG) in cerebrospinal fluid (CSF) of patients with active multiple sclerosis (MS) and with other neurological diseases (OND). Comparable levels of precipitation of radiolabeled MAG were obtained with CSF from the patients of the two groups.
E
E
Nobile-Orazio
G
G
Spagnol
G
G
Scarlato
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid / Q000276:immunology; D051379:Mice / Q000276:immunology; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid* / Q000276:immunology; D009185:Myelin Proteins / Q000134:cerebrospinal fluid* / Q000276:immunology; D018992:Myelin-Associated Glycoprotein; D011863:Radioimmunoassay
D000911:Antibodies, Monoclonal; D007074:Immunoglobulin G; D009185:Myelin Proteins; D018992:Myelin-Associated Glycoprotein