Multiple sclerosis. Magnetic resonance imaging, evoked potentials and cerebrospinal fluid analysis.
We have studied 27 patients with multiple sclerosis (22 definite, 5 probable) by magnetic resonance imaging (MRI), visual evoked potentials (VEPs), brainstem auditory evoked potentials (BAEPs), and oligoclonal bands (OBs) in cerebrospinal fluid (CSF), MRI was altered in 92.5% of the cases, the presence of OBs in CSF was revealed in 73.1% of the examined patients, the frequency of evoked potentials (EPs) alteration was VEPs = 59.3% and BAEPs = 29.6%, at least one of the two EPs occurred positive in 66.6% of the cases. Our data confirm the more sensitive value of MRI compared with OBs and EPs studies in assessing MS, and stress the utility of the combined use of these tests.
Institute of Neurology, Catholic University of Rome.
P
P
David
G P
GP
Ristori
M
M
Elia
A
A
Bartoli
A
A
Ciervo
A R
AR
Massaro
G
G
Carbone
D000293:Adolescent; D000328:Adult; D001921:Brain / Q000503:physiopathology; D001933:Brain Stem; D005072:Evoked Potentials, Auditory; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid / Q000175:diagnosis*