Nutritional and immunological investigations in head and neck cancer patients before and after therapy.
We studied the nutritional and immunological states of 20 patients with advanced head and neck carcinomas. Treatment included chemotherapy with methotrexate, cis-platinum and bleomycin prior to operation and radiotherapy. Nutritional and immunological parameters were examined before and after each therapy given. Most of these parameters decreased during chemotherapy. However, while we found that nutrition improved or normalized by the end of the primary tumor treatment, immunologic parameters failed to change significantly.
Picker
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Bichler
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D000328:Adult; D000368:Aged; D001761:Bleomycin / Q000627:therapeutic use; D001798:Blood Proteins / Q000032:analysis; D001835:Body Weight; D002802:Cholinesterases / Q000097:blood; D002945:Cisplatin / Q000627:therapeutic use; D006258:Head and Neck Neoplasms / Q000276:immunology* / Q000532:radiotherapy / Q000628:therapy; D006801:Humans; D007958:Leukocyte Count; D008214:Lymphocytes; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D009747:Nutritional Physiological Phenomena; D011379:Prognosis; D012177:Retinol-Binding Proteins / Q000032:analysis; D012882:Skin Tests; D013997:Time Factors; D014801:Vitamin A / Q000097:blood
D001798:Blood Proteins; D012177:Retinol-Binding Proteins; D001761:Bleomycin; D014801:Vitamin A; D002802:Cholinesterases; D002945:Cisplatin; D008727:Methotrexate