Acute lymphoblastic leukemia with t(4;11) in a patient previously exposed to a carcinogen.
A case of early B t(4;11)(q21;q23) acute lymphoblastic leukemia (ALL) with low white blood cell (WBC) count, without splenomegaly, short survival time, in a patient previously exposed to benzol is presented. We discuss the relationship between the t(4;11)(q21;q23) and the exposure to a carcinogen.
Departament de Biologia Cel.lulari Fisiologia, Facultat de Ciències, Universitat Autònoma de Barcelona, Spain.
F
F
Solé
M R
MR
Caballín
M D
MD
Coll
S
S
Woessner
J
J
Egozcue
D001554:Benzene / Q000633:toxicity*; D002880:Chromosomes, Human, Pair 11; D002894:Chromosomes, Human, Pair 4; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced* / Q000235:genetics; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000139:chemically induced* / Q000235:genetics; D014178:Translocation, Genetic
D005819:Genetic Markers; D001554:Benzene