[Serotonin and its metabolites in the cerebrospinal fluid and blood of patients with tumors of the spinal cord].
Twenty-six patients with extra- and intramedullary tumors of the spinal cord had a considerably increased content of serotonin, 5-hydroxyindoleacetic acid, and melatonin in the cerebrospinal fluid (highest in patients with total blockade of the subarachnoid space) as well as of serotonin in blood platelets. The results of tests for serotonin metabolism can be used as a diagnostic test in the early stages of the tumor growth and are an additional factor in determining the indications for contrast examination of patients with a suspected spinal tumor.
Makarov
A Iu
AIu
Pomnikov
V G
VG
Sheludchenko
F I
FI
D000328:Adult; D000368:Aged; D002781:Cholesteatoma / Q000134:cerebrospinal fluid*; D005260:Female; D006394:Hemangiosarcoma / Q000134:cerebrospinal fluid*; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000134:cerebrospinal fluid; D008297:Male; D008550:Melatonin / Q000134:cerebrospinal fluid; D008577:Meningeal Neoplasms / Q000134:cerebrospinal fluid*; D008579:Meningioma / Q000134:cerebrospinal fluid*; D008875:Middle Aged; D009442:Neurilemmoma / Q000134:cerebrospinal fluid*; D012701:Serotonin / Q000134:cerebrospinal fluid*; D013118:Spinal Cord Diseases / Q000134:cerebrospinal fluid*; D013120:Spinal Cord Neoplasms / Q000134:cerebrospinal fluid*
D012701:Serotonin; D006897:Hydroxyindoleacetic Acid; D008550:Melatonin
Serotonin i ego metabolity v likvore i krovi bol'nykh s opukholiami spinnogo mozga.