Human placental tissue stimulates bovine capillary endothelial cell growth, migration and protease production.
A crude extract of human placenta has been demonstrated to stimulate growth, motility and the production of the proteases plasminogen activator and collagenase in cultured bovine capillary endothelial cells. These data are in keeping with the presence of an angiogenic factor(s) in human placenta.
M
M
Presta
P
P
Mignatti
D E
DE
Mullins
D A
DA
Moscatelli
D002455:Cell Division; D002465:Cell Movement; D004727:Endothelium / Q000166:cytology* / Q000201:enzymology; D006801:Humans; D003012:Microbial Collagenase / Q000378:metabolism; D009389:Neovascularization, Pathologic; D010447:Peptide Hydrolases / Q000378:metabolism; D010920:Placenta / Q000098:blood supply* / Q000502:physiology; D010959:Tissue Plasminogen Activator / Q000378:metabolism
D010447:Peptide Hydrolases; D010959:Tissue Plasminogen Activator; D003012:Microbial Collagenase