Comparison of pancreatic digestive enzyme secretion induced by volatile fatty acids in mice, Japanese field voles and goats.
The secretory response of the exocrine pancreas to volatile fatty acids was investigated in the isolated preparations of mice, Japanese field voles and goats. The amylase content in pancreases of the voles was half that of the mice, and the trypsin content was four times higher than that of the mice. Amylase release to volatile fatty acids in the goats showed a dose-dependent relationship. The response in the voles was obtained by acetate and propionate, but preparations in the mice were ineffective in response to volatile fatty acids. The results indicate that the pancreatic digestive enzyme secretory function in voles resembles that of ruminants.
Harada
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D000681:Amylases / Q000378:metabolism*; D000818:Animals; D003411:Arvicolinae; D001786:Blood Glucose / Q000032:analysis; D001835:Body Weight; D002217:Carbachol / Q000494:pharmacology; D005232:Fatty Acids, Volatile / Q000494:pharmacology*; D006041:Goats; D007700:Kinetics; D051379:Mice; D009929:Organ Size; D010179:Pancreas / Q000033:anatomy & histology / Q000187:drug effects; D010189:Pancreatic Juice / Q000187:drug effects / Q000201:enzymology*; D013045:Species Specificity; D014357:Trypsin / Q000378:metabolism
D001786:Blood Glucose; D005232:Fatty Acids, Volatile; D002217:Carbachol; D000681:Amylases; D014357:Trypsin