RNA-like conformational properties of a synthetic DNA poly(dA-dU).poly(dA-dU).
Differences in the circular dichroism of poly(dA-dT).poly(dA-dT) and poly(dA-dU).poly(dA-dU) and in its temperature induced changes are reported. A comparison to the data obtained with DNA and RNA indicates that an absence of thymine methyl groups in the polynucleotide results in promoting its RNA-like conformational properties. However, poly(dA-dU).poly(dA-dU) is not an A-DNA type of double helix.
Kypr
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Vorlícková
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D000818:Animals; D002417:Cattle; D002942:Circular Dichroism; D004247:DNA / Q000032:analysis*; D003854:Deoxyribonucleotides / Q000032:analysis*; D009690:Nucleic Acid Conformation; D011063:Poly A-U / Q000032:analysis*; D011089:Polydeoxyribonucleotides; D012313:RNA / Q000032:analysis*
D003854:Deoxyribonucleotides; D011089:Polydeoxyribonucleotides; D011063:Poly A-U; C020468:poly(d(A-U)); D012313:RNA; D004247:DNA