Continuous vasopressin replacement in diabetes insipidus.
Five children who developed diabetes insipidus as a manifestation of severe brain injury received continuous intravenous treatment with a solution containing both aqueous vasopressin and appropriate crystalloid replacement. Polyuria, hypernatraemia, and decreased urine osmolalities were safely corrected in all patients within eight to 28 hours.
Intensive Care Unit, Royal Children's Hospital, Victoria, Australia.
C
C
Ralston
W
W
Butt
D000293:Adolescent; D001930:Brain Injuries / Q000150:complications; D002648:Child; D003919:Diabetes Insipidus / Q000188:drug therapy* / Q000209:etiology / Q000652:urine; D006801:Humans; D007223:Infant; D007262:Infusions, Intravenous; D009994:Osmolar Concentration; D012964:Sodium / Q000652:urine; D014667:Vasopressins / Q000008:administration & dosage / Q000627:therapeutic use*
D014667:Vasopressins; D012964:Sodium