Rapid response of patients simultaneously treated with lithium and nortriptyline.
To shorten the latency-to-response time for antidepressant treatment, three patients diagnosed with major depression were treated simultaneously with lithium and nortriptyline. Symptoms responded markedly by Day 7 and completely resolved by Day 14. Patients experienced few side effects.
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425.
L S
LS
Austin
G W
GW
Arana
J C
JC
Ballenger
D000328:Adult; D002986:Clinical Trials as Topic; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D004359:Drug Therapy, Combination; D005260:Female; D006760:Hospitalization; D006801:Humans; D008094:Lithium / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009661:Nortriptyline / Q000627:therapeutic use*; D011569:Psychiatric Status Rating Scales
D008094:Lithium; D009661:Nortriptyline