[Evaluation of the effectiveness of general anesthesia with kalipsol in congenital heart defects based on indicators of contraction, relaxation and pump function of the myocardium and systemic and pulmonary hemodynamics].
Calipsol has no significant effect on the preload, cardiac pump function and systemic arterial pressure. Patients with congenital heart valve defects under calipsol anesthesia reveal different hemodynamic changes in systemic and pulmonary circulation; left ventricular afterload is increased, which leads to an enhancement in left ventricular work. The type of general anesthesia under study decreases right ventricular afterload and right ventricular work. The deterioration in myocardial relaxation in patients with congenital heart valve defects is accompanied by the improvement of myocardial contractility, which necessitates different approaches to calipsol administration in patients with cyanotic and acyanotic heart valve defects.
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D000293:Adolescent; D000768:Anesthesia, General; D002648:Child; D002675:Child, Preschool; D005112:Extracorporeal Circulation; D006330:Heart Defects, Congenital / Q000503:physiopathology / Q000601:surgery*; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D007432:Intraoperative Period; D007649:Ketamine / Q000008:administration & dosage* / Q000494:pharmacology*; D009200:Myocardial Contraction / Q000187:drug effects* / Q000502:physiology
D007649:Ketamine
Otsenka éffektivnosti obshcheĭ anestezii kalipsolom pri vrozhdennykh porokakh serdtsa po pokazateliam sokratimosti, rasslavleniia, nasosnoĭ funktsii miokarda, sistemnoĭ i legochnoĭ gemodinamiki.