Acetylated fetal haemoglobin in neonates born to mothers with established and gestational diabetes.
Birth weight ratios (BWRs) and cord blood C-peptide values were significantly higher in neonates born to mothers with well-controlled gestational diabetes (GD) than in those born to mothers with well-controlled established diabetes (ED) or mothers with normal results on glucose tolerance testing. The neonates born to the ED mothers had the highest cord blood acetylated fetal haemoglobin (Hb F1) values, and these values correlated with cord C-peptide values. The cord C-peptide values in the GD group correlated with BWRs, but not with Hb F1 values. These results suggest differential tissue utilization of glucose in neonates born to mothers with different types of diabetes.
Macfarlane
C M
CM
Tsakalakos
N
N
Taljaard
J J
JJ
D001724:Birth Weight; D002096:C-Peptide / Q000097:blood; D005260:Female; D005312:Fetal Blood / Q000032:analysis*; D005319:Fetal Hemoglobin / Q000031:analogs & derivatives* / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011254:Pregnancy in Diabetics
D002096:C-Peptide; C028560:acetylated human fetal hemoglobin; D005319:Fetal Hemoglobin