Cerebrospinal fluid amino acid and monoamine metabolite levels of Papio papio: correlation with photosensitivity.
Several putative neurotransmitter amino acids and monoamine metabolites were measured in the cerebrospinal fluid of spontaneously photosensitive baboons (Papio papio) at different periods with varying degrees of photosensitivity in the same animals. At maximum photosensitivity the inhibitory amino acids gamma-aminobutyric acid and taurine were lower, and those of asparagine (metabolite of the excitatory amino acid aspartate) were higher, than when the animals were not photosensitive. Thus a decreased inhibition and perhaps increased excitation correlates with the level of photosensitivity.
K G
KG
Lloyd
B
B
Scatton
C
C
Voltz
P
P
Bryere
A
A
Valin
R
R
Naquet
D000596:Amino Acids / Q000134:cerebrospinal fluid*; D000818:Animals; D001679:Biogenic Amines / Q000134:cerebrospinal fluid*; D004827:Epilepsy / Q000134:cerebrospinal fluid*; D005260:Female; D006719:Homovanillic Acid / Q000134:cerebrospinal fluid; D006897:Hydroxyindoleacetic Acid / Q000134:cerebrospinal fluid; D008297:Male; D008734:Methoxyhydroxyphenylglycol / Q000134:cerebrospinal fluid; D010215:Papio; D010775:Photic Stimulation / Q000009:adverse effects; D013654:Taurine / Q000134:cerebrospinal fluid; D005680:gamma-Aminobutyric Acid / Q000134:cerebrospinal fluid
D000596:Amino Acids; D001679:Biogenic Amines; D013654:Taurine; D008734:Methoxyhydroxyphenylglycol; D006897:Hydroxyindoleacetic Acid; D005680:gamma-Aminobutyric Acid; D006719:Homovanillic Acid