Models of localized energy coupling.
It is proven that any model of localized protonmotive energy coupling that relies upon properties of a homogeneous surface phase must, when operated in the steady state, lead to bulk phase electrochemical potentials for protons that are as large as those required by the delocalized chemiosmotic theory. To obtain models consistent with experiments supporting localized energy coupling requires some kind of surface heterogeneity for the proton conducting pathways. Two general classes of heterogeneous surface models are mentioned. One class involves phase-separated lipid domains. The second class involves hydrogen-bonded chains in proteins that traverse the membrane laterally.
J F
JF
Nagle
R A
RA
Dilley
D001693:Biological Transport, Active; D002462:Cell Membrane / Q000378:metabolism; D004734:Energy Metabolism; D007473:Ion Channels / Q000378:metabolism*; D007700:Kinetics; D008563:Membrane Lipids / Q000378:metabolism; D008954:Models, Biological; D011522:Protons
D007473:Ion Channels; D008563:Membrane Lipids; D011522:Protons