[Histo-autoradiographic study of the secretion of gastric mucus in the rat stomach. II. Role of feeding and its combination with an antacid].
The authors use the technique of histoautoradiography after injection of glucose 3H to study the production and excretion of acid mucus in the fundus mucosa of the rat stomach. They demonstrate the effect of fasting, of eating and of eating combined with a topical agent consisting of 3 active principles: beidellitic montmorillonite, aluminum hydroxide and magnesium hydroxide. Eating stimulates the excretion of mucus during the digestive phase. Gelox combined with food allows for the late creation (6 to 12 hours after the meal) of an abundant layer of protective mucus. This topical action on the secretion of acid mucus favourises the physiological protection of the gastric mucosa.
J G
JG
Rateau
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N
Maurin
D000536:Aluminum Hydroxide / Q000494:pharmacology*; D000538:Aluminum Silicates / Q000494:pharmacology*; D000818:Animals; D001345:Autoradiography; D001546:Bentonite / Q000494:pharmacology*; D004338:Drug Combinations / Q000494:pharmacology; D004435:Eating; D005215:Fasting; D005260:Female; D005752:Gastric Mucins / Q000378:metabolism*; D008274:Magnesium / Q000494:pharmacology*; D008276:Magnesium Hydroxide / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D013270:Stomach / Q000187:drug effects*
D000538:Aluminum Silicates; D004338:Drug Combinations; D005752:Gastric Mucins; D001546:Bentonite; D000536:Aluminum Hydroxide; C041775:Gelox; D008274:Magnesium; D008276:Magnesium Hydroxide
Etude histo-autoradiographique de la sécreétion du mucus gastrique del l'estomac du rat. II. Rôle de l'alimentation et de son avec l'administration d'une anti-acide.