Systemic polychemotherapy in patients with mycosis fungoides and lymph node involvement: a follow-up study of 17 patients.
Seventeen patients with mycosis fungoides and lymph node involvement were treated with polycytostatic courses consisting of cyclophosphamide, vincristin (Oncovin) and prednisone (COP). A response rate of 76% was found. In 7 patients (41%) a complete remission and in 6 patients (35%) a partial remission was obtained. The actuarial survival rate at 5 years was 64%. This treatment was well-tolerated by most patients and severe side effects were not observed.
H J
HJ
Sentis
R
R
Willemze
W A
WA
Van Vloten
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D011241:Prednisone / Q000627:therapeutic use; D011879:Radiotherapy Dosage; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D013997:Time Factors; D014750:Vincristine / Q000627:therapeutic use
D014750:Vincristine; D003520:Cyclophosphamide; D011241:Prednisone