Synthesis of poly-L-glutamates containing 5-substituted uracil moieties.
The polymer reaction of cyclic derivatives of uracil and 5-bromouracil with polyacrylic and polymethacrylic acids, and poly-L-glutamic acid was studied in dimethylformamide solution. A similar reaction of cyclic derivatives of uridine with the polymeric acids was also made. Alkaline hydrolysis was further carried out on the polymers obtained.
Mochizuki
E
E
Inaki
Y
Y
Takemoto
K
K
D007202:Indicators and Reagents; D007700:Kinetics; D010455:Peptides / Q000138:chemical synthesis*; D011099:Polyglutamic Acid / Q000031:analogs & derivatives / Q000138:chemical synthesis*; D013329:Structure-Activity Relationship; D014498:Uracil
D007202:Indicators and Reagents; D010455:Peptides; D011099:Polyglutamic Acid; D014498:Uracil