[Causes of death in hemophilia patients in East Germany].
By means of the Central Card Index of Haemophilia, a working material of the Section of Haemophilia in the Society of Haematology and Blood Transfusion of the GDR, 52 patients with heriditary haemorrhagic diatheses could be registered. These persons had died between 1962 and 1984. The average age of death amounted to 33.8 years. With 23 cases intracranial bleedings were the dominating cause of death in all haemophiliacs. From this fact the absolute necessity arises to initiate a substitutive therapy with a sufficiently high dosage, if there is an assumption of a craniocerebral trauma and, in addition, to treat hypertension in such a way that normotonic values are achieved. Even retrospectively no signs of an acquired immunodeficiency syndrome could be found in any of the patients. As haemophilic bleedings apparently represented the life limiting factors in the majority of the deceased, the importance of an early adequate substitutive therapy is stressed, the principles of which should be known to all general practioners.
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WG
Schiller
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Hartmann
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Remde
D000163:Acquired Immunodeficiency Syndrome / Q000401:mortality; D000293:Adolescent; D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000401:mortality; D002543:Cerebral Hemorrhage / Q000401:mortality; D002648:Child; D002675:Child, Preschool; D003327:Coronary Disease / Q000401:mortality; D003430:Cross-Sectional Studies; D005859:Germany, East; D006467:Hemophilia A / Q000401:mortality*; D002836:Hemophilia B / Q000401:mortality; D006470:Hemorrhage / Q000401:mortality; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000401:mortality; D008103:Liver Cirrhosis / Q000401:mortality; D008875:Middle Aged
Todesursachen von Hämophiliepatienten in der DDR.