[The immunological reactivity indices (the humoral component) in persons in contact with mycotoxin-contaminated food products].
Blood serum levels of immunoglobulins (IgG, IgA, IgM, IgD, IgE), concentration of complement components (C1-inhibitor, C3, C4, C5, C9) as well as the content of some protein fractions (transferrin, ceruloplasmin, haptoglobin, orosomucoid, alpha 1-antitrypsin, alpha 2-macroglobulin, albumin and prealbumin) in the plasma were assayed in subjects exposed (due to their occupational necessity) to food raw materials (wheat, corn, barley, combined fodder) contaminated with mycotoxins. A total of 50 subjects, who have been working from 1 to 15 years at grain-treating factories, were investigated. It has been shown that a long-term exposure to food and fodder products containing mycotoxins induces a growth of IgE level attended by a drop in IgG content, and a decrease in the concentration of the complement components C3 and C9, transferrin and orosomucoid.
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D000917:Antibody Formation / Q000187:drug effects / Q000276:immunology; D000937:Antigen-Antibody Reactions / Q000187:drug effects* / Q000276:immunology; D001798:Blood Proteins / Q000032:analysis; D003165:Complement System Proteins / Q000032:analysis; D004781:Environmental Exposure; D005506:Food Contamination; D005524:Food Technology; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D009183:Mycotoxins / Q000009:adverse effects*; D013997:Time Factors
D001798:Blood Proteins; D007136:Immunoglobulins; D009183:Mycotoxins; D003165:Complement System Proteins
Sostoianie nekotorykh pokazateleĭ immunologicheskoĭ reaktivnosti (gumoral'nogo zvena) u lits, kontaktiruiushchikh s zagriaznennymi mikotoksinami pishchevymi produktami.