title: The effect of malathion on RNA polymerase activity of cell nuclei and transcription products in lymphocyte culture.
abstract: Malathion decreased polymerase activity of cell nuclei and inhibited RNA synthesis in cultured lymphocytes. The mechanism of action of this compound at the cellular level is suggested.
mesh_terms: D002467:Cell Nucleus / Q000187:drug effects* / Q000201:enzymology; D002478:Cells, Cultured; D012321:DNA-Directed RNA Polymerases / Q000037:antagonists & inhibitors*; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects* / Q000378:metabolism; D008294:Malathion / Q000633:toxicity*; D012313:RNA / Q000096:biosynthesis; D014158:Transcription, Genetic / Q000187:drug effects*
chemical_list: D012313:RNA; D012321:DNA-Directed RNA Polymerases; D008294:Malathion