Serological characterisation of a mouse monoclonal anti-P-like antibody.
An IgM mouse monoclonal antibody, LM 147/328, raised against an Escherichia coli immunogen, was found to possess anti-P-like specificity. It is proposed that this antibody recognises an epitope on a Gal beta 1-3GalNAc disaccharide structure (GalNAc = N-acetyl-D-galactosamine). The haemagglutinating activity of this antibody was consistently strong with adult erythrocytes, but gave significantly weak reactions with about 7% of cord erythrocyte samples.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D001789:Blood Group Antigens / Q000276:immunology*; D000939:Epitopes / Q000276:immunology; D005312:Fetal Blood / Q000276:immunology; D006384:Hemagglutination; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology; D051379:Mice; D010127:P Blood-Group System / Q000276:immunology*; D014281:Trihexosylceramides / Q000097:blood / Q000276:immunology
D000911:Antibodies, Monoclonal; D001789:Blood Group Antigens; D000939:Epitopes; D007075:Immunoglobulin M; D010127:P Blood-Group System; D014281:Trihexosylceramides