title: Mapping and gene order of U1 small nuclear RNA, endogenous viral env sequence, amylase, and alcohol dehydrogenase-3 on mouse chromosome 3.
abstract: Linkage was established between a number of genes that map on chromosome 3 by studying the distribution patterns of DNA polymorphisms and protein electrophoretic mobility polymorphisms in recombinant inbred (RI) strains of mice. This analysis resulted in the following suggested gene order between the newly assigned genes and previously mapped genes: gamma-fibrinogen (Fgg), Xmmv-22 of mink cell focus-inducing (MCF) virus, U1b small nuclear RNA gene cluster (Rnu-1b), amylase (Amy-1,2), cadmium resistance (cdm), alcohol dehydrogenase-3 (Adh-3), alcohol dehydrogenase-1 (Adh-1). In situ hybridization to chromosome spreads confirmed the assignment of the Ulb small nuclear RNA (snRNA) gene cluster and the gamma-fibrinogen gene to the center of chromosome 3.
mesh_terms: D000426:Alcohol Dehydrogenase / Q000235:genetics; D000681:Amylases / Q000235:genetics; D000818:Animals; D002871:Chromosome Banding; D002874:Chromosome Mapping; D005340:Fibrinogen / Q000235:genetics; D005819:Genetic Markers; D007621:Karyotyping; D051379:Mice; D008908:Mink Cell Focus-Inducing Viruses / Q000235:genetics; D005810:Multigene Family; D009693:Nucleic Acid Hybridization; D012150:Polymorphism, Restriction Fragment Length; D012342:RNA, Small Nuclear / Q000235:genetics; D014759:Viral Envelope Proteins / Q000235:genetics
chemical_list: D005819:Genetic Markers; D012342:RNA, Small Nuclear; D014759:Viral Envelope Proteins; D005340:Fibrinogen; D000426:Alcohol Dehydrogenase; D000681:Amylases