title: Prospective study of central nervous system changes in children with acute lymphoblastic leukemia receiving two different methods of central nervous system prophylaxis.
mesh_terms: D000293:Adolescent; D001215:Asparaginase / Q000627:therapeutic use; D002490:Central Nervous System / Q000473:pathology*; D002648:Child; D002986:Clinical Trials as Topic; D004569:Electroencephalography; D006801:Humans; D007275:Injections, Intravenous; D007278:Injections, Spinal; D007945:Leukemia, Lymphoid / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D007958:Leukocyte Count; D015122:Mercaptopurine / Q000627:therapeutic use; D008727:Methotrexate / Q000008:administration & dosage / Q000627:therapeutic use; D004676:Myelin Basic Protein / Q000032:analysis; D011241:Prednisone / Q000627:therapeutic use; D011446:Prospective Studies; D011897:Random Allocation; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D004676:Myelin Basic Protein; D014750:Vincristine; D015122:Mercaptopurine; D001215:Asparaginase; D011241:Prednisone; D008727:Methotrexate