A small catalytic oligoribonucleotide.
A 19-nucleotide RNA fragment can cause rapid, highly specific cleavage of a 24-nucleotide RNA fragment under physiological conditions. Because each 19-mer can participate in many cleavage reactions, this molecule has all the properties associated with an RNA enzyme.
D002413:Cations, Divalent; D004247:DNA; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008274:Magnesium / Q000494:pharmacology; D015636:Magnesium Chloride; D009843:Oligoribonucleotides / Q000378:metabolism*; D012313:RNA / Q000096:biosynthesis; D016337:RNA, Catalytic; D012335:RNA, Ribosomal / Q000378:metabolism*; D013604:T-Phages / Q000201:enzymology; D013698:Templates, Genetic
D002413:Cations, Divalent; D009843:Oligoribonucleotides; D016337:RNA, Catalytic; D012335:RNA, Ribosomal; D015636:Magnesium Chloride; D012313:RNA; D004247:DNA; D012321:DNA-Directed RNA Polymerases; D008274:Magnesium