title: Ionic channels: I. The biophysical basis for ion passage and channel gating.
abstract: This article reviews the biophysics of ion passage through membrane pores, as well as the physical factors that control the ion selectivity, gating, and conductance of an ionic channel. Different voltage clamp techniques are discussed in detail. The biophysical properties of sodium channels are reviewed.
mesh_terms: D000200:Action Potentials; D000818:Animals; D004594:Electrophysiology / Q000379:methods; D007473:Ion Channels / Q000378:metabolism / Q000502:physiology*; D008433:Mathematics; D008564:Membrane Potentials; D008839:Microelectrodes; D009132:Muscles / Q000378:metabolism / Q000502:physiology; D009474:Neurons / Q000378:metabolism / Q000502:physiology; D011930:Reaction Time / Q000502:physiology
chemical_list: D007473:Ion Channels