Cytosine arabinoside-induced differentiation and killing: unresolved questions.
A brief survey of the problems related to leukemic cell differentiation is proposed. The role of cytosine-arabinoside among the differentiation inducers and its potential clinical utility is discussed on the basis of the present literature. The authors report a case of myelomonocytic leukemia which displayed a differentiative response to cytarabine treatment.
D000368:Aged; D002454:Cell Differentiation / Q000187:drug effects*; D003561:Cytarabine / Q000494:pharmacology* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007951:Leukemia, Myeloid / Q000473:pathology; D008297:Male
D003561:Cytarabine