title: Two new fluorescent derivatives of progesterone to use in fluoroimmunoassay.
abstract: Synthesis, fluorometric and immunological properties of two new fluorescent derivatives of progesterone are reported. Both compounds were obtained from 11 alpha-hydroxyprogesterone 11-hemisuccinate; the fluorescent molecules were joined to the steroid by bifunctional arms. The first of these is cysteamine whose thiol group was reacted with N-(3-fluoranthenyl) maleimide, and the second is tyramine whose phenolic group was reacted with 1-nitroso-2 naphthol.
mesh_terms: D003429:Cross Reactions; D000939:Epitopes; D005456:Fluorescent Dyes; D007118:Immunoassay / Q000379:methods; D011374:Progesterone / Q000031:analogs & derivatives* / Q000032:analysis / Q000138:chemical synthesis / Q000276:immunology
chemical_list: D000939:Epitopes; D005456:Fluorescent Dyes; D011374:Progesterone