title: [Reaction of the protein-synthesizing apparatus of the major stomach cells in rats to thyroxine administration].
abstract: Electron microscopy and cytochemical analysis have shown that protein-synthesizing apparatus of major stomach cells was characterized by the most pronounced changes observed in cell structures. Comparison between ultrastructural and biochemical analysis demonstrating leucine and orotic acid incorporation into the total protein and RNA, respectively, has revealed the correlation between the structure of nucleus, nucleolia and biosynthesizing activity of secretory cells. It was established that, while in parietal cells the enzymes at the organella level affected mainly mitochondria, in major cells protein-synthesizing apparatus was involved.
mesh_terms: D000818:Animals; D005753:Gastric Mucosa / Q000378:metabolism; D008297:Male; D014176:Protein Biosynthesis; D012313:RNA / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013270:Stomach / Q000187:drug effects* / Q000648:ultrastructure; D013974:Thyroxine / Q000494:pharmacology*; D013997:Time Factors
chemical_list: D012313:RNA; D013974:Thyroxine
vernacular_title: Reaktsiia beloksinteziruiushchego apparata glavnykh kletok zheludka krys na vvedenie tiroksina.