A comparison of rapid adenine nucleotide incorporation into phosphoglyceroyl-ATP and into RNA-like species in perfused rat heart.
Four main species of rapidly synthesised trichloroacetic acid-insoluble derivatives of adenylate can be separated in extracts from rat hearts. The major species, accounting for more than 70% of the total, is phosphoglyceroyl-ATP; two others (16% of the total) are closely related to it. Around 10% of incorporated radioactivity is in a high-molecular-weight form with a phosphate/purine ratio of 0.8; comparison of [14C]uridylate and [14C]adenylate incorporation supports the suggestion that this is a rapidly synthesised species of RNA which represents about 4% of total RNA in heart. Values are given for the contents of UTP, UDP and UDPglucose in adult rat hearts.
D000255:Adenosine Triphosphate / Q000031:analogs & derivatives* / Q000096:biosynthesis; D000818:Animals; D003609:Dactinomycin / Q000494:pharmacology; D005994:Glycerophosphates / Q000096:biosynthesis*; D009206:Myocardium / Q000378:metabolism*; D012313:RNA / Q000096:biosynthesis*; D051381:Rats; D014158:Transcription, Genetic / Q000187:drug effects; D014530:Uridine Diphosphate / Q000032:analysis; D014532:Uridine Diphosphate Glucose / Q000032:analysis; D014544:Uridine Triphosphate / Q000032:analysis
D005994:Glycerophosphates; C049248:phosphoglyceroyl-ATP; D003609:Dactinomycin; D014530:Uridine Diphosphate; D012313:RNA; D000255:Adenosine Triphosphate; D014544:Uridine Triphosphate; D014532:Uridine Diphosphate Glucose