Pregnancy-specific parameters in early pregnancies after in vitro fertilization: prediction of the course of pregnancy.
The plasma concentrations of the beta subunit of human chorionic gonadotropin (beta-hCG), pregnancy-specific glycoprotein, and progesterone were measured in 37 pregnancies after in vitro fertilization. Twenty-one pregnancies ended with delivery, 9 as clinical abortions, and 7 as biochemical abortions. To predict the pregnancy outcome as early as possible, we designed a prediction graph by calculating a "cutoff line" using discriminant analysis and prediction bands up to 95% probability. This prediction graph can help in the estimation of the probability of pregnancy outcome with satisfactory reliability by determination of beta-hCG only.
D000022:Abortion, Spontaneous / Q000097:blood; D006063:Chorionic Gonadotropin / Q000097:blood; D018997:Chorionic Gonadotropin, beta Subunit, Human; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D010446:Peptide Fragments / Q000097:blood; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011268:Pregnancy-Specific beta 1-Glycoproteins / Q000032:analysis; D011374:Progesterone / Q000097:blood; D011379:Prognosis; D013223:Statistics as Topic
D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D010446:Peptide Fragments; D011268:Pregnancy-Specific beta 1-Glycoproteins; D011374:Progesterone