Intravenous gammaglobulin therapy for neonatal alloimmune thrombocytopenia.
A clinical experience with the combined use of intravenous gammaglobulin and platelet transfusions in a neonate with alloimmune thrombocytopenia secondary to PLA1 incompatibility is described and compared to a previously affected sibling treated with a conventional regimen of corticosteroids, random donor platelet transfusions, and exchange transfusion for neonatal alloimmune thrombocytopenia.
D000906:Antibodies / Q000032:analysis; D001803:Blood Transfusion; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007116:Immunization, Passive / Q000379:methods*; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D008297:Male; D010976:Platelet Count; D017713:Platelet Transfusion; D013921:Thrombocytopenia / Q000209:etiology / Q000276:immunology / Q000628:therapy*; D005719:gamma-Globulins / Q000008:administration & dosage*
D000906:Antibodies; D005719:gamma-Globulins