[Current results with surgery and adjuvant chemotherapy in malignant melanoma].
The paper presents the results of three randomized trials for adjuvant chemo- and immunotherapy in malignant melanoma clinical stage II: 770 patients were treated by surgery, surgery + DTIC, surgery + BCG or surgery + DTIC + BCG, 248 patients were treated by surgery or surgery + poly-U-A; 40 patients were treated by surgery or surgery + vinblastine/bleomycine/cisplatinum. Neither the recidive free interval nor the survival could be enhanced by surgically adjuvant chemo- and immunotherapy in this group of patients.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001500:BCG Vaccine / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage; D002945:Cisplatin / Q000008:administration & dosage; D002986:Clinical Trials as Topic; D003606:Dacarbazine / Q000627:therapeutic use; D006801:Humans; D008545:Melanoma / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D011897:Random Allocation; D014747:Vinblastine / Q000008:administration & dosage
D001500:BCG Vaccine; D001761:Bleomycin; D014747:Vinblastine; D003606:Dacarbazine; D002945:Cisplatin
Aktuelle Ergebnisse zur chirurgisch adjuvanten Chemotherapie beim malignen Melanom.