Diagnosis of anterior chamber metastasis by serologic marker found during anterior chamber paracentesis.
A 29-year-old man developed anterior uveitis unresponsive to intensive topical and systemic therapy. He had recently completed a course of chemotherapy with apparent response and resolution of metastasis from a mixed germ cell tumor (embryonal carcinoma and seminoma). Anterior chamber paracentesis was nondiagnostic on two occasions for metastatic cells. At the time of his second paracentesis a tumor marker, human chorionic gonadotropin-beta subunit, was used to confirm the diagnosis of anterior chamber metastasis to the eye.
D000328:Adult; D000867:Anterior Chamber / Q000032:analysis; D001826:Body Fluids / Q000032:analysis; D006063:Chorionic Gonadotropin / Q000097:blood*; D018997:Chorionic Gonadotropin, beta Subunit, Human; D004407:Dysgerminoma / Q000097:blood / Q000175:diagnosis* / Q000556:secondary; D005134:Eye Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000556:secondary; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D010446:Peptide Fragments / Q000097:blood*; D013396:Suction / Q000379:methods; D013724:Teratoma / Q000097:blood / Q000175:diagnosis* / Q000556:secondary
D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D010446:Peptide Fragments