[Proliferation of cultured endothelial cells under the effect of aprotinin and 4-aminomethylbenzoic acid].
Though the migration of cultivated endothelial cells is decreased by aprotinin, their proliferation is not influenced. The inhibition of migration caused by PAMBA is lower than that caused by aprotinin. PAMBA, however, inhibits the proliferation of endothelial cells. Simultaneous application of both agents is not more effective than PAMBA alone. The probability of the intracellular action of PAMBA is discussed.
D010129:4-Aminobenzoic Acid / Q000494:pharmacology*; D062365:Aminobenzoates / Q000494:pharmacology*; D000818:Animals; D001011:Aorta; D007611:Aprotinin / Q000494:pharmacology*; D002417:Cattle; D002455:Cell Division / Q000187:drug effects; D002465:Cell Movement / Q000187:drug effects; D004347:Drug Interactions; D004727:Endothelium / Q000166:cytology* / Q000187:drug effects; D062366:para-Aminobenzoates
D062365:Aminobenzoates; D062366:para-Aminobenzoates; C015668:4-aminomethylbenzoic acid; D007611:Aprotinin; D010129:4-Aminobenzoic Acid
Proliferation kultivierter Endothelzellen unter dem Einfluss von Aprotinin und 4-Aminomethylbenzoesäure.