A rare blood group antigen, Ola (Oldeide), associated with weak Rh antigens.
A 'new', rare blood group antigen, Ola (Oldeide), is described. Only one Ol(a+) person was found among the 7,151 blood donors tested. Examination of the family of the proposita revealed 10 additional Ol(a+) persons. The study indicated that Ola is inherited as a Mendelian dominant character and segregates independently of the ABO, MNSs, P, Rh and Kidd blood group systems, of the ABH secretor genes, and of sex. Ol(a+) family members had depressed Rh antigens, while the Ol(a-) members had Rh antigens of normal strength. The depression was particularly pronounced for the C and E antigens, less marked for the D antigen. Individual antisera differed in their ability to demonstrate the presence of the antigens. Depression of the c and e antigens could not be demonstrated conclusively with the antisera available.
D001789:Blood Group Antigens / Q000235:genetics* / Q000276:immunology; D000939:Epitopes / Q000032:analysis* / Q000235:genetics; D005260:Female; D006801:Humans; D009664:Norway; D010375:Pedigree; D012204:Rh-Hr Blood-Group System / Q000235:genetics* / Q000276:immunology
D001789:Blood Group Antigens; D000939:Epitopes; D012204:Rh-Hr Blood-Group System