The effects of carbamazepine and sodium valproate on SEPs and BAEPs.
SEPs and BAEPs were studied in 36 previously untreated epileptics receiving either carbamazepine (CBZ) or sodium valproate (VPA) monotherapy. CBZ prolonged central conduction times in SEPs and BAEPs. SEP latency prolongation correlated with serum CBZ levels. VPA had minimal effects on evoked potentials. The present study gives evidence of similar effects of carbamazepine and phenytoin on central neural conduction.
D000328:Adult; D000368:Aged; D001933:Brain Stem / Q000503:physiopathology*; D002220:Carbamazepine / Q000494:pharmacology* / Q000627:therapeutic use; D004827:Epilepsy / Q000188:drug therapy / Q000503:physiopathology; D005072:Evoked Potentials, Auditory / Q000187:drug effects*; D005073:Evoked Potentials, Somatosensory / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014635:Valproic Acid / Q000494:pharmacology* / Q000627:therapeutic use
D002220:Carbamazepine; D014635:Valproic Acid