Ultrastructural study of Chlamydia trachomatis surface antigens by immunogold staining with monoclonal antibodies.
Surface antigens of Chlamydia trachomatis were studied by immunogold staining with monoclonal antibodies and by electron microscopy. The serovar- and subspecies-specific epitopes were the most surface accessible. The species- and genus-specific epitopes were the least surface exposed. Similar serological specificity as that in the microimmunofluorescence test was demonstrated by immunogold staining.
D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial / Q000302:isolation & purification*; D000954:Antigens, Surface / Q000302:isolation & purification; D002692:Chlamydia trachomatis / Q000276:immunology* / Q000648:ultrastructure; D000939:Epitopes / Q000302:isolation & purification; D006046:Gold; D008854:Microscopy, Electron; D013045:Species Specificity
D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial; D000954:Antigens, Surface; D000939:Epitopes; D006046:Gold