title: Irrelevant IgE binding to cellulose discs in RAST.
abstract: This study describes two sera that showed irrelevant IgE binding to all allergen-coated cellulose discs tested. This irrelevant IgE binding was not observed when allergen extracts were coupled to agarose beads. Such irrelevant IgE binding can be detected using human serum albumin-coated discs.
mesh_terms: D000328:Adult; D001666:Binding Sites, Antibody; D002482:Cellulose / Q000494:pharmacology*; D003429:Cross Reactions; D005109:Extracellular Matrix / Q000276:immunology; D005189:False Positive Reactions; D005260:Female; D006636:Histamine Release / Q000187:drug effects; D006801:Humans; D007073:Immunoglobulin E / Q000378:metabolism*; D007962:Leukocytes / Q000276:immunology; D008297:Male; D011485:Protein Binding; D011852:Radioallergosorbent Test / Q000379:methods; D011863:Radioimmunoassay / Q000379:methods; D012685:Sepharose / Q000494:pharmacology; D012709:Serum Albumin / Q000494:pharmacology
chemical_list: D012709:Serum Albumin; D007073:Immunoglobulin E; D002482:Cellulose; D012685:Sepharose