title: Experimental studies on red cell-based assays for total IgE and allergen-specific IgE.
abstract: The potential of red cell-based assays for IgE and allergen-specific IgE has been examined using mouse monoclonal anti-human IgE antibodies and chimaeric human IgE anti-4-hydroxy-3-iodo-5-nitrophenacetyl. Experiments concerned with developing a red cell IgE antibody-capture assay for allergen-specific IgE have pointed to the advantages of presenting the allergen on a second agglutinable red cell.
mesh_terms: D000485:Allergens / Q000276:immunology; D000818:Animals; D000888:Antibodies, Anti-Idiotypic / Q000378:metabolism; D000911:Antibodies, Monoclonal / Q000378:metabolism; D002417:Cattle; D002678:Chimera; D000939:Epitopes; D004912:Erythrocytes / Q000276:immunology*; D006388:Hemagglutinins / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis* / Q000276:immunology; D012756:Sheep; D012995:Solubility
chemical_list: D000485:Allergens; D000888:Antibodies, Anti-Idiotypic; D000911:Antibodies, Monoclonal; D000939:Epitopes; D006388:Hemagglutinins; D007073:Immunoglobulin E