Expression of functional potassium channels from Shaker cDNA in Xenopus oocytes.
The Shaker gene of Drosophila melanogaster encodes a potassium-selective ion channel, the 'A' channel, or one of its subunits. A single Shaker messenger RNA species suffices to direct the synthesis of functional A channels in Xenopus oocytes. Physiological characteristics of the A currents induced by two different mRNA species are compared.
D000818:Animals; D004247:DNA / Q000235:genetics*; D004331:Drosophila melanogaster / Q000235:genetics*; D007267:Injections; D007473:Ion Channels / Q000378:metabolism* / Q000502:physiology; D007700:Kinetics; D009154:Mutation; D009865:Oocytes / Q000378:metabolism*; D011188:Potassium / Q000378:metabolism*; D012333:RNA, Messenger / Q000494:pharmacology; D014981:Xenopus / Q000378:metabolism*
D007473:Ion Channels; D012333:RNA, Messenger; D004247:DNA; D011188:Potassium