title: Clinical application of prostatic markers. I. Classification of prostatic tumours using immunohistochemical techniques.
abstract: Immunohistochemical techniques using antibodies to prostate specific antigen (PSA) and prostate specific acid phosphatase (PAP) have greatly increased the feasibility of reliable diagnosis of primary or metastatic prostatic carcinoma. A review of the literature showed the diagnostic specificity of antibodies to PSA or PAP to be 100% and 87-100%, respectively. The corresponding figures for diagnostic sensitivity were 94-100% and 90-100%.
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism*; D000230:Adenocarcinoma / Q000378:metabolism*; D000951:Antigens, Neoplasm / Q000032:analysis*; D014408:Biomarkers, Tumor / Q000032:analysis*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D011467:Prostate / Q000378:metabolism*; D017430:Prostate-Specific Antigen; D011471:Prostatic Neoplasms / Q000378:metabolism*
chemical_list: D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D000135:Acid Phosphatase; D017430:Prostate-Specific Antigen