title: Gangliocytic paraganglioma of the duodenum: case report.
abstract: A case of gangliocytic paraganglioma of the second portion of the duodenal loop is presented. The tumor was polypoid and, histologically, composed of mature ganglion cells, spindle cells and epithelial-like cells. Immunocytochemical examination demonstrated the presence of neurofilament 200 K and S-100 protein only in the first two types of cells; all the cells were positive for neuron-specific enolase. The reaction for cytokeratin was negative in all neoplastic components. According to morphologic and immunocytochemical findings, we suggest a hamartomatous nature of this entity.
mesh_terms: D000328:Adult; D004379:Duodenal Neoplasms / Q000032:analysis / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D005724:Ganglia / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D007382:Intermediate Filaments / Q000032:analysis; D007633:Keratins / Q000032:analysis; D010235:Paraganglioma / Q000032:analysis / Q000473:pathology* / Q000648:ultrastructure
chemical_list: D007633:Keratins