Converting enzyme inhibitors and the cardiovascular system.
Most commonly used drugs reduce blood pressure equally. Reduction in pressure lessens the chance of stroke but appears to have little impact on death from ischaemic heart disease in the majority. Loss of arterial compliance, development of cardiac hypertrophy, impaired coronary blood flow, and dysrhythmias may contribute, at least in part, to the adverse cardiac effects of hypertension. It is speculated that converting enzyme inhibitors could offer beneficial effects in these areas.
D000806:Angiotensin-Converting Enzyme Inhibitors; D002318:Cardiovascular Diseases / Q000188:drug therapy*; D002319:Cardiovascular System / Q000187:drug effects*; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans
D000806:Angiotensin-Converting Enzyme Inhibitors