Continuous-flow fast atom bombardment mass spectrometry.
The continuous-flow fast atom bombardment probe performs equally well with or without a high-performance liquid chromatography column producing clean spectra containing little or no background noise. Its function as a liquid chromatography-mass spectrometry interface for labile and involatile samples has been illustrated with reference to dansylated amino acids. The versatility of the new probe has been exemplified by on-line enzymatic peptide sequencing.
D000596:Amino Acids / Q000032:analysis*; D002853:Chromatography, Liquid; D003524:Cyclosporins / Q000032:analysis; D003619:Dansyl Compounds / Q000032:analysis; D013058:Mass Spectrometry; D010455:Peptides / Q000032:analysis; D013056:Spectrophotometry, Ultraviolet; D013373:Substance P / Q000032:analysis
D000596:Amino Acids; D003524:Cyclosporins; D003619:Dansyl Compounds; D010455:Peptides; D013373:Substance P