The relevance of clinical and laboratory data at diagnosis to survival time of chronic granulocytic leukemia patients.
Clinical and laboratory data were investigated in 80 patients diagnosed during the chronic phase of CGL. Comparison has been made between the group of 24 patients surviving longer than 5 years vs. a group of 56 patients surviving shorter than 5 years. Additionally, a group of 6 patients surviving longer than 10 years was analysed separately. According to our findings the most favourable prognostic factors at diagnosis are: young age, normal hemoglobin level, leukocytosis less than 60 X 10(9)/l, absence of splenomegaly indicating rather a small tumour mass in the body.
D000328:Adult; D001752:Blast Crisis / Q000473:pathology; D001773:Blood Cells / Q000473:pathology; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000175:diagnosis* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D011379:Prognosis