DNA-binding fingers encoded by a trypanosome retroposon.
A Trypanosoma brucei repeated DNA element (TRS-1, for trypanosome repeated sequence), which seems transposable, may encode a 1651 amino acid polypeptide showing homology with reverse transcriptase. This polypeptide would also carry a DNA-binding domain, as suggested by the presence of five DNA-binding "fingers" homologous to those of the transcription factor TFIIIA of Xenopus laevis and retroviral DNA-binding proteins.
D000818:Animals; D004247:DNA; D004251:DNA Transposable Elements; D004268:DNA-Binding Proteins; D008969:Molecular Sequence Data; D012194:RNA-Directed DNA Polymerase / Q000235:genetics; D012091:Repetitive Sequences, Nucleic Acid; D014346:Trypanosoma brucei brucei / Q000235:genetics*
D004251:DNA Transposable Elements; D004268:DNA-Binding Proteins; D004247:DNA; D012194:RNA-Directed DNA Polymerase