title: Human fibrin glue versus sutures in periodontal surgery.
abstract: A fibrin-sealing system consisting of symmetrical flap and graft procedures versus silk sutures in a split-mouth clinical trial was tested in 51 patients. Clinical parameters and operative times were recorded and compared. In clinical use, the fibrin glue provided quick hemostasis and adequate tissue adhesion on the whole inner surface of grafts or flaps. Its use saved remarkable amounts of time and made it easier to fix tissues in difficult areas. The time saved ranged from 3 to 19.5 minutes per procedure, and 1 to 8.5 minutes per tooth. The convenience of the fibrin glue was especially appreciated in pedicle flap procedures.
mesh_terms: D000293:Adolescent; D000328:Adult; D007611:Aprotinin / Q000627:therapeutic use*; D002648:Child; D004338:Drug Combinations / Q000627:therapeutic use; D005176:Factor XIII / Q000627:therapeutic use*; D005260:Female; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen / Q000627:therapeutic use*; D006801:Humans; D019476:Insect Proteins; D008297:Male; D008875:Middle Aged; D010510:Periodontal Diseases / Q000601:surgery*; D011506:Proteins; D047011:Silk; D013524:Surgical Flaps; D013537:Sutures; D013917:Thrombin / Q000627:therapeutic use*; D013997:Time Factors; D014014:Tissue Adhesives / Q000627:therapeutic use*; D014945:Wound Healing
chemical_list: D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D019476:Insect Proteins; D011506:Proteins; D047011:Silk; D014014:Tissue Adhesives; D005340:Fibrinogen; D005176:Factor XIII; D007611:Aprotinin; D013917:Thrombin