Characterization of monoclonal antibodies specific for human Tamm-Horsfall protein.
Fifteen monoclonal antibodies have been produced to human Tamm-Horsfall protein (THP), identifying at least seven distinct epitopes. The antibodies have been used to isolate from serum an immunoreactive protein which comigrates with urinary THP. In addition, the antibodies may prove useful to set up an immunoenzymoassay for urinary THP as well as for immunoaffinity purification.
D000911:Antibodies, Monoclonal / Q000276:immunology*; D000918:Antibody Specificity; D000939:Epitopes; D006801:Humans; D007124:Immunoenzyme Techniques; D009088:Mucoproteins / Q000032:analysis / Q000276:immunology*; D058949:Uromodulin
D000911:Antibodies, Monoclonal; D000939:Epitopes; D009088:Mucoproteins; C548612:UMOD protein, human; D058949:Uromodulin