Modulation of cytotoxicity and metabolism of 5-fluorouracil in two intestine cell lines.
D002453:Cell Cycle / Q000187:drug effects; D002460:Cell Line; D004247:DNA / Q000378:metabolism; D004357:Drug Synergism; D005467:Floxuridine / Q000633:toxicity*; D005472:Fluorouracil / Q000378:metabolism / Q000633:toxicity*; D006801:Humans; D019271:Hypoxanthine; D007042:Hypoxanthines / Q000378:metabolism; D066298:In Vitro Techniques; D007288:Inosine / Q000031:analogs & derivatives / Q000378:metabolism / Q000494:pharmacology; D009943:Organophosphorus Compounds / Q000378:metabolism / Q000494:pharmacology; D010430:Pentosyltransferases / Q000378:metabolism; D057845:Pyrimidine Phosphorylases; D012313:RNA / Q000378:metabolism; D012267:Ribosemonophosphates / Q000378:metabolism; D013936:Thymidine / Q000494:pharmacology; D013940:Thymidylate Synthase / Q000378:metabolism
D007042:Hypoxanthines; D009943:Organophosphorus Compounds; D012267:Ribosemonophosphates; D005467:Floxuridine; D019271:Hypoxanthine; C023477:diisopropyl methylphosphonate; D007288:Inosine; D012313:RNA; D004247:DNA; D013940:Thymidylate Synthase; D010430:Pentosyltransferases; D057845:Pyrimidine Phosphorylases; C012271:deoxyinosine; D005472:Fluorouracil; C025034:doxifluridine; D013936:Thymidine