Elevated second trimester maternal serum alpha-fetoprotein and cytomegalovirus infection.
A case is presented of intrauterine cytomegalovirus infection. Initially, the infection was most probably manifested by elevated second trimester maternal serum alpha-fetoprotein levels. Placental involvement by the infectious agent may have produced the elevations in maternal serum. Alpha-fetoprotein elevation unrelated to fetal anatomic abnormalities, twins, or incorrect dates may represent a potential marker of placental pathology.
D000293:Adolescent; D003586:Cytomegalovirus Infections / Q000097:blood* / Q000175:diagnosis; D005260:Female; D005317:Fetal Growth Retardation / Q000175:diagnosis; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000097:blood*; D000509:alpha-Fetoproteins / Q000378:metabolism*
D000509:alpha-Fetoproteins