Temporal control of bovine herpesvirus 1 glycoprotein synthesis.
The gI, gIII, and gIV glycoproteins are major bovine herpesvirus 1 antigens involved in virus neutralization. Results indicate that the gI and gIV glycoproteins were expressed as beta proteins, whereas the gIII glycoprotein was expressed strictly as a gamma protein. These findings suggest that gI and gIV may be superior to gIII as vaccine candidates.
D000818:Animals; D000956:Antigens, Viral / Q000096:biosynthesis / Q000276:immunology; D002417:Cattle; D002460:Cell Line; D003513:Cycloheximide; D000939:Epitopes / Q000276:immunology; D006023:Glycoproteins / Q000096:biosynthesis* / Q000276:immunology; D007242:Herpesvirus 1, Bovine / Q000276:immunology / Q000378:metabolism*; D007118:Immunoassay; D013997:Time Factors; D014764:Viral Proteins / Q000096:biosynthesis* / Q000276:immunology; D014765:Viral Vaccines
D000956:Antigens, Viral; D000939:Epitopes; D006023:Glycoproteins; D014764:Viral Proteins; D014765:Viral Vaccines; D003513:Cycloheximide