title: Vasculitis simulating eczematous dermatitis due to C2 deficiency.
abstract: In a patient with total C2 deficiency and repeated respiratory infections a papulovesicular rash showed to be due to leukocytoclastic vasculitis. The patient's brother also had a total deficiency of C2 but no clinical symptoms. HLA-investigation in both him and the proband showed the genotype commonly reported in cases with homozygous C2 deficiency. Their heterozygous mother and sister had slightly decreased C2 levels.
mesh_terms: D000328:Adult; D003175:Complement C2 / Q000172:deficiency*; D003876:Dermatitis, Atopic / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006680:HLA Antigens / Q000032:analysis; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D008297:Male; D014657:Vasculitis / Q000175:diagnosis / Q000276:immunology*
chemical_list: D003175:Complement C2; D006680:HLA Antigens