Opsonic activity of anti-flagellar serum against Clostridium chauvoei by mouse polymorphonuclear leucocytes.
The role of anti-flagellar serum against Clostridium chauvoei in phagocytosis by mouse polymorphonuclear leucocytes was examined. Anti-flagellar serum markedly increased phagocytic rate against the flagellated strain Okinawa but not against a non-flagellated mutant (NFM) derived from the same strain, while anti-NFM serum increased the phagocytic rate against both strains. These results indicate that anti-flagellar serum exerts its protective effect by opsonic activity.
D000372:Agglutination Tests; D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology; D003013:Clostridium / Q000276:immunology*; D005260:Female; D005407:Flagella / Q000276:immunology*; D007106:Immune Sera / Q000276:immunology; D051379:Mice; D009504:Neutrophils / Q000276:immunology*; D019081:O Antigens; D009895:Opsonin Proteins / Q000276:immunology*; D010587:Phagocytosis
D000942:Antigens, Bacterial; C022863:H antigen; D007106:Immune Sera; D019081:O Antigens; D009895:Opsonin Proteins