[Can macromolecules be absorbed and what effect does the immune status have on it?].
It was shown by means of radioactive labelling that adult animals and humans are also able to absorb protein intact in its biological active form from the gastro-intestinal tract. A large part of these macromolecules retains their original biological activity. Depending on size, particles (polls, synthetic particles) can also be absorbed. The energy supply is not influenced by this phenomenon. It is postulated that a rudimentary mechanism present in the lymphatic system of the gastro-intestinal tract is involved. This absorbation mechanism receives information from the immune system about foreign and the body's own substances and about useful and unuseful nutriment. On the basis of investigations, carried out by us, it is speculated that immunological information takes place over the lymphatic tissue of the gastro-intestinal tract and is passed on the lymphatic system.
D000818:Animals; D000941:Antigens / Q000276:immunology; D003602:Cytotoxicity, Immunologic; D006801:Humans; D007408:Intestinal Absorption; D007413:Intestinal Mucosa / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology; D051381:Rats; D005719:gamma-Globulins / Q000378:metabolism*
D000941:Antigens; D005719:gamma-Globulins
Werden Makromoleküle resorbiert und welchen Einfluss hat dabei die Immunitätslage?