Occurrence of ABO group antigens in bladder carcinoma.
Biopsies of bladder carcinoma obtained from 46 patients were tested for the presence of the group antigens, A, B and H. Lack of the antigens was confirmed in 69.6% of the samples examined. On the basis of histopathologic studies the patients were divided into three groups. The lack of the group antigens was reported in 86.4% bladder carcinoma patients; the lowest (45.5%) in the group of patients with papilloma of bladder. In cases of tumors with intermediate differentiation of tissue, the number of patients showing lack of group antigens amounted to 61.5%. Clinical observations carried out for five years suggest that the lack of group antigens is related to a recurrence of bladder carcinoma.
D000017:ABO Blood-Group System / Q000276:immunology*; D000372:Agglutination Tests; D000954:Antigens, Surface / Q000032:analysis*; D002277:Carcinoma / Q000453:epidemiology / Q000276:immunology*; D000939:Epitopes / Q000032:analysis; D006801:Humans; D010212:Papilloma / Q000276:immunology; D001749:Urinary Bladder Neoplasms / Q000453:epidemiology / Q000276:immunology*
D000017:ABO Blood-Group System; D000954:Antigens, Surface; D000939:Epitopes