Hb F-Xinjiang or A gamma T25(B7)Gly----Arg: a new slow-moving unstable fetal hemoglobin variant.
This report describes a new fetal hemoglobin variant, Hb F-Xinjiang, which was observed in a newborn baby of the Han nationality. Its electrophoretic mobility at pH 8.6 was slower than that of Hb D. Structural analyses identified the variant as A gamma T25(B7)Gly----Arg. Heat stability test showed that the variant was unstable.
D000595:Amino Acid Sequence; D004588:Electrophoresis, Cellulose Acetate; D005260:Female; D005312:Fetal Blood / Q000032:analysis*; D005319:Fetal Hemoglobin / Q000032:analysis*; D006455:Hemoglobins, Abnormal / Q000032:analysis*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008969:Molecular Sequence Data; D010449:Peptide Mapping
D006455:Hemoglobins, Abnormal; C054743:hemoglobin F Xingjiang; D005319:Fetal Hemoglobin