title: The presence of substance P-immunoreactive nerve fibres in the organum vasculosum laminae terminalis of the Mongolian gerbil (Meriones unguiculatus).
abstract: Serial frontal and sagittal sections through the organum vasculosum laminae terminalis (OVLT) of the male Mongolian gerbil (Meriones unguiculatus) were incubated with an antibody against substance P and stained by the indirect peroxidase anti-peroxidase technique. A high density of nerve fibres with large-sized terminals exhibiting substance P-immunoreactivity was observed in the OVLT in close relation to the blood vessels both in the internal and the external zone of the organ. In addition, a few fibres penetrated into the ependyma covering the organ. These results indicate that substance P is released into the bloodstream from the OVLT and in addition might influence the ependymal cells bordering the organ towards the third ventricle.
mesh_terms: D000818:Animals; D001921:Brain / Q000166:cytology*; D005849:Gerbillinae; D007124:Immunoenzyme Techniques; D008297:Male; D009474:Neurons / Q000166:cytology*; D013373:Substance P / Q000032:analysis*
chemical_list: D013373:Substance P