title: Anterograde transsynaptic transport of WGA-HRP in rat olfactory pathways.
abstract: The transport of wheat germ agglutinin conjugated to horseradish peroxidase (WGA-HRP) was studied in rat olfactory pathways. After applications of tracer to the vomeronasal organ, the olfactory epithelium or injections into the olfactory bulb, WGA-HRP reaction product was observed in second-order neuron terminal areas of each pathway, e.g. within posteromedial cortical amygdaloid nucleus, primary olfactory cortex and contralateral primary olfactory cortex, respectively. The results indicate that anterograde transsynaptic transport of WGA-HRP occurs in olfactory pathways, as has been shown in visual, somatosensory and limbic systems, and thus, anterograde transsynaptic transport may be a mechanism for neurons to exchange materials and/or messages.
mesh_terms: D000818:Animals; D001692:Biological Transport; D002450:Cell Communication; D002490:Central Nervous System / Q000378:metabolism*; D006735:Horseradish Peroxidase; D008032:Limbic System / Q000378:metabolism; D009830:Olfactory Bulb / Q000378:metabolism; D009833:Olfactory Pathways / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013194:Staining and Labeling; D013569:Synapses / Q000378:metabolism; D014909:Wheat Germ Agglutinins
chemical_list: D014909:Wheat Germ Agglutinins; D006735:Horseradish Peroxidase