title: [Use of monospecific antibodies for determining the antigenic determinant composition in the hemagglutinins of the H3N2 influenza viruses of 1979-1983].
abstract: The study of the antigenic composition of hemagglutinins of influenza H3N2 viruses isolated during epidemic outbreaks in 1979-1983, carried out by means of monospecific antibodies to individual antigenic determinants, showed heterogeneity of the antigenic structure of epidemically active variants. Some variants were antigenically identical to A/Bangkok/1/79 virus. Hemagglutinin structure of A/Shanghai/31/80, A/Philippines/2/82 and the like was found to contain a qualitatively new antigenic determinant heretofore undetectable in H1N1, H3N2 viruses.
mesh_terms: D000327:Adsorption; D000914:Antibodies, Viral / Q000276:immunology*; D000918:Antibody Specificity; D000939:Epitopes / Q000032:analysis*; D014644:Genetic Variation; D006389:Hemagglutinins, Viral / Q000032:analysis*; D007158:Immunologic Techniques; D053122:Influenza A Virus, H3N2 Subtype; D009980:Influenza A virus / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D000939:Epitopes; D006389:Hemagglutinins, Viral
vernacular_title: Ispol'zovanie monospetsificheskikh antitel dlia opredeleniia sostava antigennykh determinant v gemaggliutininakh virusov grippa H3N2 1979-1983 gg.