Actin and dynein-like protein are involved in axoplasmic transport mechanism in saponized squid axons.
The particle transport in axons permeabilized with saponin was blocked by three actin-related proteins, 88 K protein/actin complex, actinogelin, and cofilin. The particle movement was reactivated by ATP, but neither by GTP nor by ITP. We conclude that an actin and a dynein-like protein are involved in retrograde phase of axoplasmic transport mechanism.
D000199:Actins / Q000502:physiology*; D000251:Adenosine Triphosphatases / Q000502:physiology*; D000818:Animals; D001370:Axonal Transport; D001369:Axons / Q000502:physiology*; D049832:Decapodiformes / Q000502:physiology; D004398:Dyneins / Q000502:physiology*; D012503:Saponins
D000199:Actins; D012503:Saponins; D000251:Adenosine Triphosphatases; D004398:Dyneins