title: The treatment of stage IV carcinoma of cervix by radical dose radiotherapy.
abstract: During 1974-1979, 92 patients (14% of all carcinoma cervix cases) were assigned to Stage IV; 68 (10%) to Stage IVa and 24 (4%) to Stage IVb. Fifty-five patients were treated radically using 4 MeV X-rays (42.5 Gy in 20 fractions) followed by a 137Cs insertion (33.5 Gy to the A points). Twenty-six patients were treated palliatively and 11 received no treatment. Sixteen per cent of radically treated patients were alive at 5 years, whereas all patients treated palliatively were dead in 18 months. Pelvic tumour was eliminated in 22/55 (40%) treated radically, but in only 1/26 treated palliatively. The 5-year survival for Stage IVa treated radically was 18% and 19/44 (43%) had local tumour control. Only one patient in Stage IVb (involvement of vulva) was alive at 5 years. The overall 5-year survival for Stage IV patients in this series was 11/92 (12%).
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy; D002588:Cesium Radioisotopes / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D010166:Palliative Care; D011379:Prognosis; D011882:Radiotherapy, High-Energy; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*
chemical_list: D002588:Cesium Radioisotopes