title: High levels of interferon in synovial fluid of retrovirus-infected goats.
abstract: A high level of interferon (IFN) was found in the synovial fluid of goats with naturally acquired caprine arthritis-encephalitis (CAE), a disease caused by caprine arthritis-encephalitis virus (CAEV), a nononcogenic retrovirus of the lentivirus group. Intraarticular injection of CAEV or control inoculum in the joints of affected goats caused increased amounts of IFN production in synovial fluid.
mesh_terms: D000818:Animals; D001168:Arthritis / Q000503:physiopathology / Q000662:veterinary*; D006041:Goats; D007372:Interferons / Q000032:analysis*; D012190:Retroviridae; D012192:Retroviridae Infections / Q000503:physiopathology*; D013582:Synovial Fluid / Q000032:analysis*; D013997:Time Factors
chemical_list: D007372:Interferons