Management of immediate graft failure after cardiac transplantation using cardiopulmonary bypass and intraaortic balloon-pumping followed by cardiac retransplantation.
A 37-year-old man underwent cardiac transplantation for diffuse coronary artery disease and malignant arrhythmias. During the harvesting of the donor heart slight distention of the left ventricle was present due to insufficiency of the aortic valve. After explantation of the graft, fusion of 2 cusps was found and a commissurotomy of the aortic valve was performed and the graft transplanted. Despite maximum inotropic support immediate graft failure and aortic insufficiency was present and discontinuation of cardiopulmonary bypass (CPB) was impossible. After replacement of the aortic valve using a bioprosthesis and implantation of an intraaortic balloon-pump, low cardiac output persisted and CPB had to be continued. After 11 hours of normothermic cardiopulmonary bypass and intraaortic balloon-pumping a second graft became available and was retransplanted successfully. The postoperative course was uneventful and the patient remains well 3 months after the operation.
D000328:Adult; D001145:Arrhythmias, Cardiac / Q000150:complications / Q000601:surgery; D002315:Cardiopulmonary Bypass; D003327:Coronary Disease / Q000150:complications / Q000601:surgery; D006084:Graft Rejection; D016027:Heart Transplantation; D006801:Humans; D007423:Intra-Aortic Balloon Pumping; D008297:Male; D012086:Reoperation