title: [Optimization of the use of etmozin in treating patients suffering from frequent ventricular extrasystole].
abstract: Fifteen patients with frequent and stably recordable ventricular premature heart beat received etmozine treatment (the priming dose 500 mg, the maintenance dose 200 mg). Of these, 3 patients presented with coronary heart disease, 1 with mitral valve prolapse, and 11 with the idiopathic pattern of heart rhythm disorders. The drug was found to be highly effective. The 90% decrease in the number of ventricular premature heart beats during 2 h after administration of the priming dose can be used as criterion in predicting the efficacy of etmozine treatment.
mesh_terms: D000293:Adolescent; D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage*; D005117:Cardiac Complexes, Premature / Q000175:diagnosis / Q000188:drug therapy*; D004341:Drug Evaluation; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016293:Moricizine; D010640:Phenothiazines / Q000008:administration & dosage*; D013997:Time Factors
chemical_list: D000889:Anti-Arrhythmia Agents; D010640:Phenothiazines; D016293:Moricizine
vernacular_title: Optimizatsiia ispol'zovaniia étmozina pri lechenii bol'nykh, stradaiushchikh chastoĭ zheludochkovoĭ ékstrasistolieĭ.