[Excretion of 5-hydroxyindole-3-acetic and 5-methoxyindole-3-acetic acids in cancer patients].
Daily urinary excretion of 5-hydroxy-3-indoleacetic acid (5-HIAA) and 5-methoxyindole-3-acetic acid (5-MIAA) was studied by chromatography-mass-spectrometry in patients with cancer and healthy subjects. A considerable increase in urinary 5-MIAA-excretion was shown in patients with cancer of the stomach, rectum and lung. In some cases, a correlation was found between high urine levels of carcinogenic 5-MIAA and similarly high levels of 5-HIAA excretion with urine.
D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000031:analogs & derivatives* / Q000652:urine*; D009369:Neoplasms / Q000652:urine*; D012016:Reference Values; D012701:Serotonin / Q000378:metabolism / Q000652:urine
D012701:Serotonin; C001736:5-methoxyindoleacetic acid; D006897:Hydroxyindoleacetic Acid
Ekskretsiia 5-oksiindolil-3-uksusnoĭ i 5-metoksiindolil-3-uksusnoĭ kislot u onkologicheskikh bol'nykh.