title: Susceptibility to mercurials of clinical Pseudomonas aeruginosa isolated in México.
abstract: Susceptibility to inorganic mercuric ions and to organomercurials of 237 Pseudomonas aeruginosa clinical strains isolated in Mexico was determined by agar dilution tests. Resistant strains fell into two classes: i) narrow-spectrum resistant strains (27% of total isolates) resistant only to mercuric ions and to merbromin, and most grouped in pyocin type 1; and ii) broad-spectrum resistant strains (5%) with additional resistances to thimerosal, phenylmercury, methylmercury and p-hydroxymercuribenzoate, that belonged mostly to pyocin type 10. Mercurial resistant isolates showed a higher proportion of resistance to antibiotics and metals than did mercurial sensitive isolates, and broad-spectrum resistant strains had the highest frequency of resistance to antibiotics and to tellurite and arsenate.
mesh_terms: D006801:Humans; D006902:Hydroxymercuribenzoates / Q000494:pharmacology; D008622:Merbromin / Q000494:pharmacology; D008627:Mercuric Chloride / Q000494:pharmacology; D008628:Mercury / Q000494:pharmacology*; D008767:Methylmercury Compounds / Q000494:pharmacology; D010662:Phenylmercuric Acetate / Q000494:pharmacology; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D013849:Thimerosal / Q000494:pharmacology
chemical_list: D006902:Hydroxymercuribenzoates; D008767:Methylmercury Compounds; C030601:4-hydroxymercuribenzoate; D013849:Thimerosal; D008627:Mercuric Chloride; D008628:Mercury; D008622:Merbromin; D010662:Phenylmercuric Acetate; C004925:methylmercuric chloride