Hydrolysis of dextran metronidazole monosuccinate ester prodrugs. Evidence for participation of intramolecularly catalyzed hydrolysis of the conjugate metronidazole-succinic acid ester by the neighbouring dextran hydroxy groups.
D002851:Chromatography, High Pressure Liquid; D003911:Dextrans / Q000032:analysis*; D006868:Hydrolysis; D007700:Kinetics; D008795:Metronidazole / Q000031:analogs & derivatives* / Q000032:analysis
D003911:Dextrans; C051965:metronidazole monosuccinate-dextran conjugate; C051964:metronidazole monosuccinate; D008795:Metronidazole