title: IgG heavy-chain (Gm) allotypes in demyelinating polyneuropathy associated with MAG-binding monoclonal IgM autoantibodies.
abstract: IgG heavy-chain (Gm) allotypes were determined in 11 Caucasian patients with the syndrome of demyelinating polyneuropathy associated with monoclonal IgM autoantibodies with affinity for myelin-associated glycoprotein. The frequency of Gm phenotypes in the patient group was significantly different from that seen in a normal Caucasian population.
mesh_terms: D001323:Autoantibodies / Q000235:genetics; D001327:Autoimmune Diseases / Q000235:genetics*; D001666:Binding Sites, Antibody; D003711:Demyelinating Diseases / Q000235:genetics*; D006801:Humans; D007074:Immunoglobulin G / Q000235:genetics*; D007129:Immunoglobulin Gm Allotypes / Q000235:genetics*; D007143:Immunoglobulin Heavy Chains / Q000235:genetics*; D007075:Immunoglobulin M / Q000235:genetics*; D009185:Myelin Proteins / Q000276:immunology*; D018992:Myelin-Associated Glycoprotein; D010641:Phenotype; D011115:Polyneuropathies / Q000235:genetics*
chemical_list: D001323:Autoantibodies; D007074:Immunoglobulin G; D007129:Immunoglobulin Gm Allotypes; D007143:Immunoglobulin Heavy Chains; D007075:Immunoglobulin M; D009185:Myelin Proteins; D018992:Myelin-Associated Glycoprotein