title: [Significance of gastrointestinal microflora for the metabolism of foreign compounds].
abstract: Microbiological biotransformation as a part of metabolism of foreign compounds in general, has great toxicological consequences. An overview on the most important types of reactions is given. In detail, comparative investigations of the metabolism of gamma-HCH, azobenzene and progoitrin in germfree and conventionalized rats are described and results from the literature are presented.
mesh_terms: D000818:Animals; D013956:Antithyroid Agents / Q000378:metabolism*; D001391:Azo Compounds / Q000378:metabolism; D001419:Bacteria / Q000378:metabolism*; D001711:Biotransformation; D002432:Cecum / Q000378:metabolism; D004064:Digestive System / Q000382:microbiology*; D005243:Feces / Q000032:analysis; D005856:Germ-Free Life; D005961:Glucosinolates / Q000378:metabolism; D001556:Hexachlorocyclohexane / Q000378:metabolism; D011078:Polychlorinated Biphenyls / Q000378:metabolism; D051381:Rats
chemical_list: D013956:Antithyroid Agents; D001391:Azo Compounds; D005961:Glucosinolates; C015550:2,4',5-trichlorobiphenyl; C009048:progoitrin; D001556:Hexachlorocyclohexane; D011078:Polychlorinated Biphenyls; C009850:azobenzene
vernacular_title: Die Bedeutung der Gastrointestinalflora für den Fremdstoffmetabolismus.