title: A highly abundant transcript in adult murine cerebellar granule cells contains repetitive sequences homologous to L1.
abstract: Cloned cDNA from adult mouse cerebellum composed of subsequences homologous to the L1Md consensus sequence (long interspersed repetitive element "LINE" family of the mouse) hybridizes specifically with large nuclear poly(A)+RNAs that are highly concentrated in the murine and rat cerebellum. These homogeneous L1-related transcripts were localized in the mouse CNS by in situ hybridization with 3H- and biotin-labeled DNA probes. They were found to hybridize to cerebellar granule cells specifically.
mesh_terms: D000818:Animals; D001483:Base Sequence; D002531:Cerebellum / Q000032:analysis* / Q000166:cytology; D003001:Cloning, Molecular; D004247:DNA; D051379:Mice; D008810:Mice, Inbred C57BL; D009693:Nucleic Acid Hybridization; D011061:Poly A / Q000032:analysis; D012313:RNA / Q000032:analysis; D012333:RNA, Messenger; D012091:Repetitive Sequences, Nucleic Acid; D012689:Sequence Homology, Nucleic Acid
chemical_list: D012333:RNA, Messenger; D011061:Poly A; D012313:RNA; D004247:DNA