title: [Neuropsychological disintegration in the early ontogenesis of children from a group at high-risk of developing endogenous mental diseases].
abstract: The article is devoted to the topical questions of the study of the progeny born to patients with endogenic mental diseases, the search for psychopathological, neurological and other precursors of schizophrenia and the appearance of initial psychic disturbances associated with endogenic diseases in young children. A prospective study on the neuropsychic development of children from a high risk group has made it possible to identify specific deviations in the formation of mental and motor functions, as well as in the formation of behavioural reactions, contacts, and speech. Following specific disontogenesis some children developed psychopathological phenomena which may be considered as an onset of mental diseases at the given age. Further follow-up of this group of children will make it possible to differentiate symptoms of the disease from developmental deviations. At the present stage of the investigation it is difficult to answer the question whether the detected neuropsychic disintegration in the first years of life is only an indicator of subsequent schizophrenia.
mesh_terms: D002653:Child Behavior Disorders / Q000523:psychology; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000523:psychology*; D006801:Humans; D007223:Infant; D019964:Mood Disorders / Q000523:psychology; D011596:Psychomotor Disorders / Q000523:psychology; D012306:Risk; D012559:Schizophrenia / Q000235:genetics*; D012561:Schizophrenia, Childhood / Q000209:etiology*
vernacular_title: Nervno-psikhicheskaia dezintegratsiia v rannem ontogeneze deteĭ iz gruppy vysokogo riska po éndogennym psikhicheskim zabolevaniiam.