Axonal transport of neuroreceptors: possible involvement in long-term memory.
Evidence is presented that neuroreceptors move bidirectionally along axons of neurons through fast axoplasmic transport mechanisms. The retrograde transport of receptor-bound signal molecules from nerve terminals to the perikaryon represents a corridor of information between synapses and the cell body of neurons. It is speculated that this process could be involved in long-term memory.
D000818:Animals; D001370:Axonal Transport; D008568:Memory / Q000502:physiology*; D011956:Receptors, Cell Surface / Q000378:metabolism / Q000502:physiology; D017475:Receptors, Nerve Growth Factor; D017981:Receptors, Neurotransmitter / Q000378:metabolism / Q000502:physiology*; D011957:Receptors, Opioid / Q000378:metabolism / Q000502:physiology
D011956:Receptors, Cell Surface; D017475:Receptors, Nerve Growth Factor; D017981:Receptors, Neurotransmitter; D011957:Receptors, Opioid