Detection of an HLA-DPw1-associated epitope by an alloreactive T cell clone.
An alloreactive T cell clone was generated using HLA-A, B, C, DR, DQ, D identical, but HLA-DP different homozygous typing cells as responder and stimulator. The alloproliferative and -cytotoxic clone appears to recognize an epitope associated with HLA-DPw1.
D002999:Clone Cells; D003602:Cytotoxicity, Immunologic; D000939:Epitopes; D006681:HLA-D Antigens / Q000032:analysis*; D006682:HLA-DP Antigens / Q000032:analysis*; D059868:HLA-DP beta-Chains; D006801:Humans; D008213:Lymphocyte Activation; D013601:T-Lymphocytes / Q000276:immunology*
D000939:Epitopes; D006681:HLA-D Antigens; D006682:HLA-DP Antigens; D059868:HLA-DP beta-Chains; C054111:HLA-DPw1 antigen