[Clarifying the pathophysiologic mechanism of food allergy].
Various lymphocyte populations, dendritic cells and macrophages contribute to the intake of antigen. The transportation of antigen in the intestinal wall is possible with the help of receptive endocytosis, including extracellular protein in fluid droplets, bacterial and vegetable toxins, as well as certain viruses, which seem to be able to penetrate the cell membrane and enter directly into the cell. Own investigations: After endoscope controlled allergy-irritation of the gastro-intestinal tract, 20 people used in the clinical test showed acute signs of mucosal reaction with inflammation and swelling of the mucous membrane as well as haemorrhagic lesions. A histamine release from the mastcell was proved.
D000941:Antigens / Q000276:immunology*; D005512:Food Hypersensitivity / Q000276:immunology*; D006636:Histamine Release; D006801:Humans; D007413:Intestinal Mucosa / Q000276:immunology*; D008407:Mast Cells / Q000276:immunology
D000941:Antigens
Untersuchungen zur Klärung des pathophysiologischen Mechanismus der Nahrungsmittelallergie.