A gene locus controlling a serum protein migrating electrophoretically in the beta region of mice and detected by using a strain derived from the Japanese wild mouse (Mus musculus molossinus).
Antigenic specificities of serum proteins from the MOL-ANJ strain of mice (a strain derived from Japanese wild mice, Mus musculus molossinus) were studied by gel precipitation with alloantisera produced by reciprocal alloimmunization between MOL-ANJ and BALB/c mice. An alloantigen which migrates immunoelectrophoretically in the beta region of serum proteins has been identified. Evidence indicates that this antigenic specificity is controlled by a co-dominant autosomal gene locus designated by the symbol Sas-2. The evidence also suggests that Sas-2 is genetically different from the previously described Sas-1 which controls a serum protein in the mouse. Sas-2 was located by linkage analysis between Idh-1 locus and Akp-1 locus on chromosome 1.
D000818:Animals; D000835:Animals, Wild / Q000235:genetics; D001609:Beta-Globulins / Q000235:genetics / Q000276:immunology; D001798:Blood Proteins / Q000235:genetics* / Q000276:immunology; D002874:Chromosome Mapping; D004586:Electrophoresis; D005799:Genes, Dominant; D008040:Genetic Linkage; D005779:Immunodiffusion; D051379:Mice / Q000235:genetics* / Q000276:immunology
D001609:Beta-Globulins; D001798:Blood Proteins