Research approaches on the diagnosis of multiple sclerosis by CSF examination.
The diagnostic value of CSF oligoclonal IgG bands, intrathecal IgG synthesis, cytology and markers of myelin breakdown in the cerebro-spinal fluid were evaluated in multiple sclerosis. None of the various immunological alterations were unique to MS. The diagnosis depends therefore mainly on course and clinical symptoms, but can be supported by CSF analysis.
D002555:Cerebrospinal Fluid / Q000166:cytology*; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis*; D006801:Humans; D007136:Immunoglobulins / Q000134:cerebrospinal fluid; D007958:Leukocyte Count; D008590:Meningoencephalitis / Q000134:cerebrospinal fluid; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid* / Q000175:diagnosis; D004676:Myelin Basic Protein / Q000134:cerebrospinal fluid; D009494:Neurosyphilis / Q000134:cerebrospinal fluid; D043025:Oligoclonal Bands; D009902:Optic Neuritis / Q000134:cerebrospinal fluid; D013344:Subacute Sclerosing Panencephalitis / Q000134:cerebrospinal fluid
D002556:Cerebrospinal Fluid Proteins; D007136:Immunoglobulins; D004676:Myelin Basic Protein; D043025:Oligoclonal Bands