Axonal branching of basal forebrain projections to the neocortex: a double-labeling study in the cat.
Double-labeling of basal forebrain neurons by retrograde axonal transport demonstrates divergent collateralization among undecussated axonal projections to the neocortex. These branched fibers originate from a considerable complement of large polymorphic cell bodies located mainly in the basal nucleus of Meynert. They terminate in multiple neocortical sites including the precruciate, postcruciate and/or cingulate gyri. This extensive intra- and intergyral axonal branching indicates that neurons in the basal forebrain of the cat have extensive axonal fields innervating adjacent neocortical gyri.
D000818:Animals; D001369:Axons / Q000032:analysis*; D001479:Basal Ganglia / Q000033:anatomy & histology*; D001562:Benzimidazoles; D001931:Brain Mapping; D002415:Cats; D002540:Cerebral Cortex / Q000033:anatomy & histology*; D006735:Horseradish Peroxidase; D037102:Lectins; D009434:Neural Pathways / Q000033:anatomy & histology; D018998:Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; D000096926:Benzenesulfonamides
D001562:Benzimidazoles; D006735:Horseradish Peroxidase; D037102:Lectins; D018998:Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; C036574:nuclear yellow; D000096926:Benzenesulfonamides