The role of animal models in electrophysiologic studies of life-threatening arrhythmias.
Animal models have made substantial contributions to the understanding of basic electrophysiologic principles and arrhythmia mechanisms, as well as to the development of antiarrhythmic drugs, devices and procedures. The field of clinical electrophysiology has progressed very dramatically and there have also been advances in the basic laboratory that bear relevance to the methods, design and interpretation of clinical electrophysiologic testing, and to the application of new, potential antiarrhythmic interventions.
D000818:Animals; D001145:Arrhythmias, Cardiac / Q000503:physiopathology* / Q000628:therapy; D002304:Cardiac Pacing, Artificial; D004195:Disease Models, Animal