The influence of extracorporeal circulation on extravascular lung water in coronary surgery patients.
The influence of extracorporeal circulation (ECC) on extravascular lung water (EVLW) was investigated in a total of 45 consenting patients undergoing coronary artery bypass surgery. The patients were subdivided into 3 groups according to positive fluid balance during ECC: 1. less than 500 ml; 2. 500 to 1500 ml; 3. 1500 to 3000 ml. Lung water measurement was performed intraoperatively using the thermal green-dye double indicator dilution technique, with indocyanine green and a microprocessed lung water computer, before and after ECC. In the group with high positive fluid balance during ECC (group 3) EVLW - increase was more pronounced (5.18 ml/kg----8.18 ml/kg) than in the groups with lower positive fluid input (group 1: 5.35 ml/kg----5.68 ml/kg, group 2: 5.56 ml/kg----6.70 ml/kg). Extravascular lung water increase was accompanied by a deterioration of pulmonary gas exchange demonstrated by the greatest decrease of paO2 in group 3 (490 mmHg----243 mmHg). No significant relationship of lung water changes to various hemodynamic parameters was observed in this study.
D001834:Body Water / Q000378:metabolism*; D001026:Coronary Artery Bypass; D005110:Extracellular Space / Q000378:metabolism*; D005112:Extracorporeal Circulation; D006801:Humans; D008168:Lung / Q000378:metabolism*; D008875:Middle Aged; D010100:Oxygen / Q000378:metabolism; D013997:Time Factors; D014882:Water-Electrolyte Balance
D010100:Oxygen