title: [Symptomatic irradiation therapy of the spleen in advanced osteomyelosclerosis].
abstract: A retrospective analysis of spleen irradiation in 25 patients with progressive idiopathic myelosclerosis (agnogenic myeloid metaplasia), treated between 1948 and 1983, shows that there is a place for the mechanical effect of irradiation being an indication for its use as a palliative measure. A decrease in spleen size of varying extent was achieved in 84% of patients, while the symptoms of abdominal compression improved in 88%. Remission period averaged 10 months. On the other hand, in all seven patients in whom a decrease in the size of the spleen might have been expected to signal an improved blood picture, the frequency of transfusion remained unchanged.
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010026:Osteosclerosis / Q000150:complications / Q000532:radiotherapy*; D010166:Palliative Care; D055728:Primary Myelofibrosis / Q000150:complications / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D013154:Spleen / Q000528:radiation effects; D013163:Splenomegaly / Q000209:etiology / Q000532:radiotherapy*
vernacular_title: Symptomatische Milzbestrahlung bei fortgeschrittener Osteomyelosklerose.