title: Comparative electron histochemistry of thiamine monophosphatase and substance P in the upper dorsal horn.
abstract: The genuine marker enzyme of primary nociceptive neurons, thiamine monophosphatase (TMPase) has been localized in the substantia gelatinosa of the rat spinal cord by means of light-and electron microscopic histochemistry; localization of substance P has been studied by light-and and electron microscopic immunohistochemical methods. It has been shown that TMPase and substance P are located in two, regionally and structurally different populations of axon terminals. Substance P is contained both in A delta and in drC axons. In the postero-lateral funiculus of the white matter, substance P-positive axons establish axo-somatic synaptic contacts with large multipolar neurons of Cajal's interstitial nucleus.
mesh_terms: D000818:Animals; D001369:Axons / Q000201:enzymology; D005260:Female; D005727:Ganglia, Spinal / Q000201:enzymology*; D006651:Histocytochemistry; D007124:Immunoenzyme Techniques; D008297:Male; D008854:Microscopy, Electron; D010744:Phosphoric Monoester Hydrolases / Q000032:analysis* / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013116:Spinal Cord / Q000201:enzymology; D013373:Substance P / Q000032:analysis*
chemical_list: D013373:Substance P; C022734:thiamine monophosphatase; D010744:Phosphoric Monoester Hydrolases