[Combination of cancer markers in the detection and prognosis of digestive system tumors].
The role of carcinoembryonic antigen (CEA), gamma glutamyl transpeptidase (gamma GT), phosphohexose isomerase (PHI), pseudouridine (PSD) and acute phase reactant proteins (C-reactive protein (C-RP], alpha 1-acid glycoprotein (alpha 1-AGP) and alpha 1-antichymotrypsin (alpha 1-ACT) in distinguishing benign from malignant conditions of the digestive tract and their value in assessing the prognosis of gastrointestinal neoplasms was evaluated. For each marker it has been possible to produce a simple scoring index derived from the values found in the control population. This work suggests that pre-operative levels of certain cancer markers may be useful in tumor detection and may also give prognostic information additional to pathological staging.
D000209:Acute-Phase Proteins / Q000032:analysis*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D014408:Biomarkers, Tumor / Q000097:blood; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000097:blood* / Q000401:mortality / Q000473:pathology; D005956:Glucose-6-Phosphate Isomerase / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D011560:Pseudouridine / Q000097:blood*; D014529:Uridine / Q000031:analogs & derivatives*; D005723:gamma-Glutamyltransferase / Q000097:blood*
D000209:Acute-Phase Proteins; D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D011560:Pseudouridine; D005723:gamma-Glutamyltransferase; D005956:Glucose-6-Phosphate Isomerase; D014529:Uridine
Combinação de marcadores de câncer na detecção e prognóstico de tumores do aparelho digestivo.