[Two components of calcium-dependent potassium permeability coexist in the membrane of frog skeletal muscle].
Two components of Ca-dependent K permeabilities were demonstrated in the membrane of voltage-clamped muscles fibres by raising the internal calcium concentration with 3 mM caffeine or 0.1 microM Bay K 8644. One, which is TEA-sensitive, is enhanced by an increase of intracellular calcium and the other, which is apamin-sensitive, is inhibited by high levels of internal calcium concentration.
D001498:3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester / Q000494:pharmacology; D000818:Animals; D002110:Caffeine / Q000494:pharmacology; D002118:Calcium / Q000378:metabolism / Q000494:pharmacology*; D007473:Ion Channels / Q000187:drug effects / Q000502:physiology*; D008564:Membrane Potentials / Q000187:drug effects; D009119:Muscle Contraction / Q000187:drug effects; D009132:Muscles / Q000187:drug effects / Q000502:physiology*; D011188:Potassium / Q000378:metabolism*; D011898:Ranidae; D019789:Tetraethylammonium; D013757:Tetraethylammonium Compounds / Q000494:pharmacology
D007473:Ion Channels; D013757:Tetraethylammonium Compounds; D002110:Caffeine; D019789:Tetraethylammonium; D001498:3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; D011188:Potassium; D002118:Calcium
Deux composantes de perméabilité potassique calcium-dépendante coexistent dans la membrane du muscle squelettique de Grenouille.