Plasma requirement for expression of lupus-like anticoagulant.
Described here are five patients with lupus-like anticoagulants, four of whom required coincubation of normal plasma in order to inhibit the pro-coagulant activity of crude brain phospholipid. It is suggested that this plasma requirement for expression of anticoagulant activity is similar or identical to the "lupus-cofactor" effect described by earlier observers.
D001779:Blood Coagulation Factors / Q000097:blood / Q000276:immunology*; D003324:Coronary Artery Disease / Q000097:blood; D005260:Female; D006801:Humans; D016682:Lupus Coagulation Inhibitor; D008180:Lupus Erythematosus, Systemic / Q000097:blood; D008297:Male; D010314:Partial Thromboplastin Time; D010949:Plasma / Q000502:physiology*
D001779:Blood Coagulation Factors; D016682:Lupus Coagulation Inhibitor