A comparison of unit process systems for anchorage dependent cells.
The performance of three unit process systems for anchorage-dependent cells, namely the APV plate heat exchanger, glass bead reactor and microcarrier culture are reviewed. All three systems have been used for the production of various viruses and protein products and their use in a production process is related to various scaling-up parameters.
D000818:Animals; D001709:Biotechnology / Q000295:instrumentation*; D002448:Cell Adhesion; D002455:Cell Division; D002478:Cells, Cultured / Q000166:cytology / Q000502:physiology*; D003911:Dextrans; D005898:Glass; D013696:Temperature
D003911:Dextrans