Low material serum alpha-fetoprotein levels and congenital diaphragmatic defects.
We report on 2 cases of fetal congenital diaphragmatic defects with normal chromosomes among 105 patients referred for evaluation for low maternal serum alpha-fetoprotein (MSAFP) levels. The mechanism for this striking association is not clear. The association of low MSAFP levels and congenital diaphragmatic defects may have importance for MSAFP screening programs.
D000328:Adult; D003964:Diaphragm / Q000002:abnormalities*; D005260:Female; D006801:Humans; D011247:Pregnancy; D000509:alpha-Fetoproteins / Q000097:blood*
D000509:alpha-Fetoproteins