Human T-cell leukemia virus-associated nuclear antigen (HTLV-NA).
Replication-competent retroviruses are not known to encode or induce nuclear antigens that are immunogenic in their natural hosts. We describe here the detection of a human T-lymphotropic virus (type I and type II) associated nuclear antigen (HTLV-NA) by an anticomplement immunofluorescence assay. Antibody to HTLV-NA is detected in 18 of 68 (26%) HTLV-I seropositives.
D000956:Antigens, Viral / Q000235:genetics / Q000276:immunology; D002353:Carrier State / Q000097:blood; D002460:Cell Line; D002467:Cell Nucleus / Q000276:immunology; D003165:Complement System Proteins / Q000276:immunology; D017977:Deltaretrovirus / Q000276:immunology*; D000939:Epitopes / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D015683:Gene Products, gag; D006801:Humans; D009698:Nucleoproteins / Q000276:immunology*; D012191:Retroviridae Proteins / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology / Q000473:pathology
D000956:Antigens, Viral; D000939:Epitopes; D015683:Gene Products, gag; D009698:Nucleoproteins; D012191:Retroviridae Proteins; D003165:Complement System Proteins