title: Lymphangiosarcoma in chronic lymphedema. Reports of 3 cases and review of the literature.
abstract: Lymphangiosarcoma is an extremely rare but highly lethal complication of chronic lymphedema. The classic clinical picture is described and three cases are presented. Current concepts of etiology, histopathology, treatment and prognosis are discussed. Since early diagnosis may be the key to longer survival, all patients with chronic lymphedema should undergo careful examination at regular intervals throughout their lives.
mesh_terms: D000368:Aged; D001132:Arm; D005260:Female; D006801:Humans; D008204:Lymphangiosarcoma / Q000209:etiology* / Q000401:mortality / Q000473:pathology; D008209:Lymphedema / Q000150:complications*; D008408:Mastectomy; D008875:Middle Aged; D010166:Palliative Care; D011379:Prognosis; D012867:Skin / Q000473:pathology; D013848:Thigh