An atypical neurocognitive profile in alcoholic fathers and their sons.
Prepubescent boys and their recovering alcoholic fathers exhibited an Atypical Neurocognitive Profile consisting of (1) a reduction in amplitude of the late positive complex (LPC) of the event-related potential (ERP) during a complex visual discrimination task, and (2) reduced visuoperceptual performance evidenced by significantly lower scores on the Object Assembly, Block Design and Picture Completion subtests of the WISC-R and the Embedded Figures Test. Low LPC amplitudes were significantly correlated with poorer visuoperceptual performance. This Atypical Neurocognitive Profile may represent a marker for alcoholism.
D000328:Adult; D000437:Alcoholism / Q000235:genetics / Q000503:physiopathology*; D002648:Child; D002658:Developmental Disabilities / Q000503:physiopathology*; D004569:Electroencephalography; D005220:Fathers; D006801:Humans; D008297:Male; D008568:Memory / Q000502:physiology; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000379:methods*; D012307:Risk Factors; D014796:Visual Perception / Q000502:physiology