[Changes in the nuclei of the mammary glandular cells in the secretory cycle].
At the early stages of the secretory cycle, the activation of secretory cell nuclear chromatin is observed: the binding of acridine orange increases, while chromatin condensation in the peripheral zone of the nucleus decreases. The increase of the chromatin transcriptional activity provides for a significant increase in cytoplasmic RNA. Under the action of oxytocin reaction product granules are accumulated in conglomerates suggesting some changes in calcium distribution in the decondensed chromatin.
D000818:Animals; D002118:Calcium / Q000378:metabolism; D002466:Cell Nucleolus / Q000378:metabolism / Q000648:ultrastructure; D002467:Cell Nucleus / Q000378:metabolism / Q000648:ultrastructure*; D003593:Cytoplasm / Q000378:metabolism / Q000648:ultrastructure; D004247:DNA / Q000378:metabolism; D005260:Female; D006651:Histocytochemistry; D007774:Lactation / Q000502:physiology*; D008321:Mammary Glands, Animal / Q000378:metabolism / Q000648:ultrastructure*; D008854:Microscopy, Electron; D008857:Microscopy, Interference; D011247:Pregnancy; D012313:RNA / Q000378:metabolism; D051381:Rats
D012313:RNA; D004247:DNA; D002118:Calcium
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