[Effect of extracellular potassium ions on the potassium outward current which depends on extracellular calcium ions].
Changes in the delayed potassium outward current induced by introduction of K+ ions into extracellular solution have been studied in experiments on isolated intracellularly perfused Helix neurons. It is shown that extracellular administration of 5-10 mmol/l K+ ions into the solution produces a reversible increase of the potassium outward current which depends on the extracellular Ca2+ ions (IK(Ca out)). Extracellular potassium increases this component of the potassium current as a result of weakening of its inactivation.
D000818:Animals; D002118:Calcium / Q000502:physiology*; D004533:Egtazic Acid / Q000494:pharmacology; D005724:Ganglia / Q000187:drug effects* / Q000502:physiology; D006372:Helix, Snails; D066298:In Vitro Techniques; D007473:Ion Channels / Q000187:drug effects* / Q000502:physiology; D011188:Potassium / Q000378:metabolism* / Q000494:pharmacology*
D007473:Ion Channels; D004533:Egtazic Acid; D011188:Potassium; D002118:Calcium
Deĭstvie vnekletochnykh ionov kaliia na kalievyĭ vykhodiashchiĭ tok, zavisiashchiĭ ot vnekletochnykh ionov kal'tsiia.