[Effect of lithium oxybutyrate on lipid metabolic changes in pituitrin-induced pulmonary edema].
The experiments on white rats have confirmed that the development of lung edema following pituitrin infusion is characterized by considerable changes in phospholipid and cholesterol lung metabolism and cholesterol blood metabolism. Lithium hydroxybutyrate preinjection at a dose of 400 mg/kg prevented a decrease in cholesterol lung content and an increase in cholesterol blood plasma level which was accompanied by less prominent lung edema.
D000818:Animals; D004353:Drug Evaluation, Preclinical; D006885:Hydroxybutyrates / Q000627:therapeutic use*; D050356:Lipid Metabolism; D008168:Lung / Q000187:drug effects / Q000378:metabolism; D009929:Organ Size / Q000187:drug effects; D009942:Organometallic Compounds / Q000627:therapeutic use*; D010909:Pituitary Hormones, Posterior / Q000633:toxicity*; D011654:Pulmonary Edema / Q000139:chemically induced / Q000188:drug therapy / Q000378:metabolism*; D051381:Rats
D006885:Hydroxybutyrates; D009942:Organometallic Compounds; D010909:Pituitary Hormones, Posterior; C022826:lithium hydroxybutyrate
Vliianie oksibutirata litiia na izmeneniia lipidnogo obmena pri pituitrinovom oteke legkikh.