[Assay of chorionic gonadotrophin, follicle-stimulating hormone and alpha-fetoprotein in the efferent blood in germinal tumors of the testis].
Assays of human chorionic gonadotrophin (hCG), follicle-stimulating hormone (FSH) and alpha-foetoprotein were performed in peripheral blood and spermatic vein in 73 cases of testicular germ cell tumors. This study showed that the detection sensitivity of hCG is up to 40 times higher in the efferent blood of the tumor than in peripheral blood and that the drop in FSH concentrations often precedes a trophoblastic transformation. These results are of particular interest in the search for a minor trophoblastic or embryonic component. As a result, we propose a new strategy leading to a more efficient diagnosis and an adequate therapy.
D000328:Adult; D002822:Choriocarcinoma / Q000097:blood; D006063:Chorionic Gonadotropin / Q000097:blood*; D004407:Dysgerminoma / Q000097:blood; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000097:blood*; D009919:Orchiectomy; D011184:Postoperative Period; D011863:Radioimmunoassay; D013736:Testicular Neoplasms / Q000097:blood*; D013997:Time Factors; D000509:alpha-Fetoproteins / Q000032:analysis*
D006063:Chorionic Gonadotropin; D000509:alpha-Fetoproteins; D005640:Follicle Stimulating Hormone
Dosage de la gonadotrophine chorionique, de la folliculostimuline et de l'alpha-foetoprotéine dans le sang efférent des tumeurs germinales du testicule.