title: Ultrastructural study of Chlamydia trachomatis surface antigens by immunogold staining with monoclonal antibodies.
abstract: Surface antigens of Chlamydia trachomatis were studied by immunogold staining with monoclonal antibodies and by electron microscopy. The serovar- and subspecies-specific epitopes were the most surface accessible. The species- and genus-specific epitopes were the least surface exposed. Similar serological specificity as that in the microimmunofluorescence test was demonstrated by immunogold staining.
mesh_terms: D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial / Q000302:isolation & purification*; D000954:Antigens, Surface / Q000302:isolation & purification; D002692:Chlamydia trachomatis / Q000276:immunology* / Q000648:ultrastructure; D000939:Epitopes / Q000302:isolation & purification; D006046:Gold; D008854:Microscopy, Electron; D013045:Species Specificity
chemical_list: D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial; D000954:Antigens, Surface; D000939:Epitopes; D006046:Gold