[Blood flow in skin wound tissue and systemic hemodynamics as affected by a collagen-dalargin complex].
In has been demonstrated that a collagen-dalargin complex increases blood flow in the granulation tissue (microsphere technique) due to the formation of new capillaries and a decrease in the vascular resistance. Dalargin had no effect on the capillary blood flow in the unaffected tissues. It has been concluded that the wound healing effect of dalargin may be related to its involvement in angiogenesis regulation.
D000818:Animals; D003094:Collagen / Q000494:pharmacology*; D004743:Enkephalin, Leucine / Q000031:analogs & derivatives* / Q000494:pharmacology; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives*; D006097:Granulation Tissue / Q000098:blood supply* / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D008297:Male; D009389:Neovascularization, Pathologic / Q000139:chemically induced; D051381:Rats; D014945:Wound Healing / Q000187:drug effects
D004743:Enkephalin, Leucine; D016308:Enkephalin, Leucine-2-Alanine; D003094:Collagen; C040996:enkephalin-Leu, Ala(2)-Arg(6)-
Krovotok v tkaniakh kozhnoĭ rany i sistemnaia gemodinakika pod vliianiem kollagen-dalarginovogo kompleksa.