Lectin binding sites in duodeno-jejunal mucosae from coeliac children.
The distribution pattern of some labelled lectins (WGA, SBA, PNA, DBA, ConA, LCA) has been investigated in small intestinal mucosa of coeliac children (119 cases) and normal (short stature) and pathological (postenteritis syndrome) controls. The oligosaccharide side chains of glycoproteins present in the cytoplasm and in the brush border of enterocytes, goblet cells and luminal crypt surface have been revealed. The most important differences in lectin binding reactivity between coeliac and controls mucosae are discussed.
D001665:Binding Sites; D002446:Celiac Disease / Q000175:diagnosis / Q000378:metabolism*; D002648:Child; D002675:Child, Preschool; D004386:Duodenum / Q000032:analysis / Q000648:ultrastructure; D006801:Humans; D007223:Infant; D007413:Intestinal Mucosa / Q000032:analysis* / Q000648:ultrastructure; D007583:Jejunum / Q000032:analysis / Q000648:ultrastructure; D037102:Lectins / Q000378:metabolism*; D008871:Microvilli / Q000032:analysis; D009844:Oligosaccharides / Q000032:analysis*; D011975:Receptors, Mitogen / Q000032:analysis; D013194:Staining and Labeling
D037102:Lectins; D009844:Oligosaccharides; D011975:Receptors, Mitogen