Correlates of lateral ventricular size in chronic schizophrenia, II: biological measures.
CSF homovanillic acid levels showed a significant negative correlation with ventricle-brain ratios (VBRs) in a group of drug-free chronic schizophrenic male veterans, while CSF 5-hydroxyindoleacetic acid levels showed a similar, nearly significant trend. The response of plasma human growth hormone to 0.75 mg of apomorphine also demonstrated a significant negative correlation with VBR in this group, but other measures of central neurotransmitter activity were unrelated to ventricular size.
D000328:Adult; D001058:Apomorphine / Q000494:pharmacology; D001921:Brain / Q000033:anatomy & histology*; D002552:Cerebral Ventricles / Q000033:anatomy & histology*; D002908:Chronic Disease; D013006:Growth Hormone / Q000097:blood / Q000378:metabolism; D006719:Homovanillic Acid / Q000134:cerebrospinal fluid; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000134:cerebrospinal fluid; D008297:Male; D012559:Schizophrenia / Q000175:diagnosis*; D012636:Secretory Rate / Q000187:drug effects
D006897:Hydroxyindoleacetic Acid; D013006:Growth Hormone; D001058:Apomorphine; D006719:Homovanillic Acid