Determination of neuron specific enolase in amniotic fluid and maternal serum for the prenatal diagnosis of fetal neural tube defects.
Maternal serum neuron-specific enolase was tested as a marker for fetal nural tube defect. In around 50% of pregnancies with affected fetus the level was elevated. The increase was also found in the amniotic fluids. Normal fetal serum did not display elevation of neuron-specific enolase.
D000110:Acetylcholinesterase / Q000097:blood; D000653:Amniotic Fluid / Q000201:enzymology*; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D005865:Gestational Age; D006801:Humans; D009436:Neural Tube Defects / Q000175:diagnosis*; D010751:Phosphopyruvate Hydratase / Q000032:analysis*; D011247:Pregnancy; D011296:Prenatal Diagnosis; D000509:alpha-Fetoproteins / Q000032:analysis
D000509:alpha-Fetoproteins; D000110:Acetylcholinesterase; D010751:Phosphopyruvate Hydratase