The course of influenza virus infection in mice sensitized with hen's egg albumin.
The present study was undertaken to test the effect of sensitization of mice with ovalbumin on the course of influenza virus infection. It was shown that the endogenous interferon level as well as degree of degranulation of lung mast cells were higher in sensitized and influenza virus-infected mice than in infected and nonsensitized ones. Also, lung cells of mice subjected to influenza virus effect in vitro revealed higher degranulation degree.
D000818:Animals; D002645:Chickens; D005260:Female; D007114:Immunization; D007372:Interferons / Q000378:metabolism; D008168:Lung / Q000166:cytology / Q000276:immunology; D008297:Male; D008407:Mast Cells / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D009976:Orthomyxoviridae Infections / Q000276:immunology* / Q000503:physiopathology; D010047:Ovalbumin / Q000276:immunology*
D010047:Ovalbumin; D007372:Interferons