title: Hyalinizing plasmacytic granulomatosis of the falx.
abstract: Computed tomography scan in a 43-year-old woman revealed a fusiform mass involving the falx. Pathological tissue removed at craniotomy revealed a hyalinizing plasmacytic granulomatosis composed of masses of lymphocytes, plasmacytes, and various sized islands of hyalinized fibers arranged in parallel and surrounded by multinucleated giant cells. Ultrastructurally, the hyalinized fibers consisted of electron-dense, amorphous deposits. After partial removal, irradiation, and steroid therapy, the lesion decreased considerably in size.
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D003907:Dexamethasone / Q000627:therapeutic use; D004388:Dura Mater; D005260:Female; D006099:Granuloma / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D006818:Hyalin / Q000378:metabolism*; D008854:Microscopy, Electron; D010950:Plasma Cells / Q000473:pathology* / Q000648:ultrastructure; D014057:Tomography, X-Ray Computed
chemical_list: D003907:Dexamethasone