Synovial sarcomas. True carcinosarcomas?
The histogenesis of synovial sarcomas remains controversial. An origin from epithelium, synovium, or synovial-related cells and neural tissue has been advanced. Using a combination of a cytokeratin (epithelial marker) antibody and a vimentin (mesenchymal marker) antibody, this study suggests that a synovial sarcoma might be regarded as a carcinosarcoma. It also highlights the diagnostic utility of those antibodies in the diagnosis of synovial sarcomas.
D002296:Carcinosarcoma / Q000145:classification / Q000473:pathology; D004848:Epithelium / Q000473:pathology; D006801:Humans; D007124:Immunoenzyme Techniques; D007633:Keratins / Q000032:analysis; D008648:Mesoderm / Q000473:pathology; D012509:Sarcoma / Q000145:classification / Q000473:pathology*; D013584:Sarcoma, Synovial / Q000145:classification / Q000473:pathology*; D014746:Vimentin / Q000032:analysis
D014746:Vimentin; D007633:Keratins