title: Visual evoked potentials in a patient with prosopagnosia.
abstract: Visual evoked potentials (VEPs) were recorded from a 53-year-old man with prosopagnosia during presentation of slides of known and unknown faces and under two control conditions. ANOVA comparisons with a normal male group showed no differences in P100 amplitude, P300 amplitude or P300 latency. There were no significant evoked potential differences between the patient and controls specifically related to the face conditions. There was, however, a significant delay in the latency of P100 from both hemispheres during all types of stimuli. This prolonged latency was asymmetrical, showing a right sided emphasis with the control conditions: pattern reversal and slides of geometric designs. This finding, of a dissociation in the interhemispheric delay, provides physiological evidence of stimulus-specific organisation at an early, sensory level. The fact that the P100 component showed a marked delay, yet P300 fell within normal limits for amplitude and latency, suggests that this patient's problem lies at a perceptual level.
mesh_terms: D000377:Agnosia / Q000503:physiopathology*; D001921:Brain / Q000503:physiopathology*; D004569:Electroencephalography; D005074:Evoked Potentials, Visual; D006801:Humans; D008297:Male; D008875:Middle Aged; D010364:Pattern Recognition, Visual / Q000502:physiology