Studies on immunotropic activity of certain immunomodulators.
Immunotropic activity of natural and synthetic immunomodulators was evaluated by cytotoxic and rosette tests. In both experimental models the above groups of drugs were observed to exert similar effect. Thus, it may be assumed that synthetic immunomodulators and thymus hormones have much alike mechanisms of activity. The usefulness of both tests applied, however, differed; more sensitive appeared the model of the rosette test.
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D001388:Aziridines / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects; D003602:Cytotoxicity, Immunologic / Q000187:drug effects; D006854:Hydrocortisone / Q000494:pharmacology; D066298:In Vitro Techniques; D007542:Inosine Pranobex / Q000494:pharmacology; D051379:Mice; D012397:Rosette Formation; D013949:Thymus Extracts / Q000494:pharmacology
D000276:Adjuvants, Immunologic; D001388:Aziridines; C019108:TFX; D013949:Thymus Extracts; C016866:azimexon; D007542:Inosine Pranobex; D006854:Hydrocortisone