Renal excretion of sucrose after transfusion of sucrose containing red cell concentrates.
The elimination of sucrose from plasma and the urinary excretion after transfusions of 394 units of sucrose containing red cell concentrates (RCC) to 108 patients has been studied. 70 mmol sucrose corresponding 3 units of RCC were eliminated from the blood plasma to 90% within 3 hours and excreted by kidneys to 55-80% within 12 hours. The rate of excretion depended on the kidney function. The transfusion of RCC resuspended with the sucrose-rich CSD-AG preservation solution (80 mmol sucrose/l RCC) raised the hemoglobin concentration in patient's blood by 0.5-0.6 mmol/l related to 1 unit of RCC.
D001793:Blood Preservation / Q000379:methods*; D001803:Blood Transfusion; D017707:Erythrocyte Transfusion; D006801:Humans; D007677:Kidney Function Tests; D008657:Metabolic Clearance Rate; D013395:Sucrose / Q000008:administration & dosage / Q000652:urine*
D013395:Sucrose