Non-sutured fibrin adhesive vs. sutured anastomosis. A comparative intra-individual study in dog colon.
In each of ten dogs the colon was subjected to a two-layered sutured anastomosis and a non-sutured fibrin adhesive anastomosis. Intra-individual comparisons showed no significant difference of in vivo bursting strength after 7 days between the colon segments with sutured and those with non-sutured anastomoses. Under experimental conditions it was thus possible to achieve a safe, sutureless anastomosis in the colon using only fibrin adhesive.
D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D007611:Aprotinin / Q000627:therapeutic use*; D003106:Colon / Q000601:surgery*; D004285:Dogs; D004338:Drug Combinations / Q000627:therapeutic use; D005176:Factor XIII / Q000627:therapeutic use*; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen / Q000627:therapeutic use*; D013045:Species Specificity; D013537:Sutures; D013917:Thrombin / Q000627:therapeutic use*
D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen; D005176:Factor XIII; D007611:Aprotinin; D013917:Thrombin