title: Lamins A, B and C share an epitope with the common domain of intermediate filament proteins.
abstract: Peripheral lamina were isolated from rat liver nuclei and probed with a monoclonal antibody reactive against a common domain of all intermediate filament (IF) proteins. The antibody reacted against lamins A and C as expected from their known sequence homology with IF proteins. Lamin B was also recognized by the antibody. These results indicate that lamin B, despite important biochemical differences vs lamins A and C, also shares sequence homology with IF proteins.
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal; D000936:Antigen-Antibody Complex; D002460:Cell Line; D002467:Cell Nucleus / Q000032:analysis; D000939:Epitopes / Q000032:analysis*; D007381:Intermediate Filament Proteins / Q000032:analysis* / Q000276:immunology; D034921:Lamin Type B; D034882:Lamins; D008099:Liver / Q000032:analysis / Q000166:cytology; D051379:Mice; D009698:Nucleoproteins / Q000032:analysis* / Q000276:immunology; D051381:Rats
chemical_list: D000911:Antibodies, Monoclonal; D000936:Antigen-Antibody Complex; D000939:Epitopes; D007381:Intermediate Filament Proteins; D034921:Lamin Type B; D034882:Lamins; D009698:Nucleoproteins