Glutaraldehyde inactivated pertussis vaccine: a safe vaccine in the innocuity test.
The adsorbed diphtheria-pertussis-tetanus (DPT) vaccine containing glutaraldehyde inactivated pertussis vaccine passed the innocuity test only after one month's storage of the preparation at 4-8 degrees C when the adsorbed DPT vaccine containing pertussis vaccine inactivated by heat, formaldehyde, thimerosal or acetone did not pass the test. The adsorbed DPT vaccine became innocuous when it was stored at 4-8 degrees C. The innocuity test was passed more easily in guinea pigs than in mice.
D000818:Animals; D001681:Biological Assay; D005976:Glutaral; D006636:Histamine Release; D051379:Mice; D010567:Pertussis Vaccine / Q000009:adverse effects / Q000592:standards*
D010567:Pertussis Vaccine; D005976:Glutaral