[Liquid storage of thrombocytes: in vivo survival capability of thrombocytes after storage at +12 degrees C].
Platelet concentrates were prepared from ACD-blood and stored at +12 degrees C for 3 days with gentle agitation. The viability of the platelets was estimated by autologous transfusion of 51chromium-labeled platelets into healthy volunteers. The in vivo recovery amounted to 33.5 +/- 6.9% and mean half survival time T0,5 was 1.1 ++/- 0.2 days on the 3rd day. The control values for freshly prepared platelet concentrates were 52.5 +/- 5.9% and T0.5 3.9 +/- 0.3 days. The decrease of viability due to lowering the temperature to +12 degrees C did not correspond to the pH-value, which was well maintained in the stored platelets.
D001792:Blood Platelets / Q000502:physiology; D001793:Blood Preservation; D002470:Cell Survival; D002860:Chromium Radioisotopes; D006801:Humans; D006863:Hydrogen-Ion Concentration; D017713:Platelet Transfusion; D013696:Temperature
D002860:Chromium Radioisotopes
Zur Thrombozytenflüssiglagerung: In-vivo-Uberlebensfähigkeit von Thrombozyten nach Lagerung bei +12 grade C.