title: Activation of the mas oncogene during transfection of monoblastic cell line DNA.
abstract: Using the tumorigenicity assay, we observed an activation of the mas oncogene during transfection of human acute myelocytic leukemia (CTV-2) DNA. Respective transfectants contained amplified mas sequences characterized by rearrangements in 5' and 3' noncoding regions that were transcribed into a 3.3 kb mas RNA species. Our data represent the second report on activation of the mas gene.
mesh_terms: D000818:Animals; D004262:DNA Restriction Enzymes / Q000378:metabolism; D004273:DNA, Neoplasm / Q000378:metabolism*; D005786:Gene Expression Regulation; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D051379:Mice; D008819:Mice, Nude; D009857:Oncogenes; D011061:Poly A / Q000032:analysis; D012313:RNA / Q000032:analysis; D012333:RNA, Messenger; D014162:Transfection
chemical_list: D004273:DNA, Neoplasm; D012333:RNA, Messenger; D011061:Poly A; D012313:RNA; D004262:DNA Restriction Enzymes