Incidence of developmental handicaps among the offspring of men treated for testicular seminoma.
Although the issue of fertility in patients successfully treated for testicular seminoma seems to be resolved, it remains to be determined whether these patients can father normal, healthy children. At NYU Medical Center we have surveyed the patients treated between 1969 and 1984 who were treated with radiotherapy for testicular seminomas. The survey requested information regarding the qualitative development in offspring produced before and after radiation treatments. In the 33 patients responding we were unable to find any detrimental effect, either emotionally, physically, or developmentally in offspring sired by fathers following radiation therapy for testicular seminoma.
D002658:Developmental Disabilities / Q000209:etiology*; D004407:Dysgerminoma / Q000235:genetics* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D005298:Fertility; D006801:Humans; D007248:Infertility, Male; D008297:Male; D009367:Neoplasm Staging; D009919:Orchiectomy; D011247:Pregnancy; D011879:Radiotherapy Dosage; D013736:Testicular Neoplasms / Q000235:genetics* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery