[The protein C inhibitory system].
The chemical and physical characteristics of the individual components of the protein-C inhibiting system, protein C, thrombomodulin, protein S and the inhibitor of the activated protein C are summarized in a survey, with their mutual relations and their physiological impact on the course of the coagulating and fibrinolytic systems being represented. Finally, the clinical implications of a hereditary and acquired protein C deficiency, of a diminished protein S level and a lowered inhibitor of the activated protein C are discussed. The complications caused by a rapid decline of protein C values after administration of coumarin derivates are referred too.
D001798:Blood Proteins / Q000502:physiology*; D006801:Humans; D011486:Protein C / Q000037:antagonists & inhibitors*; D020151:Protein C Deficiency; D018046:Protein C Inhibitor
D001798:Blood Proteins; D011486:Protein C; D018046:Protein C Inhibitor
Das Inhibierungssystem des Protein C.