[Potentiation of the antiviral activity of human interferons by virazole in in vitro experiments].
Combination of interferon and virazole results in potentiation of their antiviral activity. This was demonstrated with all three types of natural interferons and the recombinant RL-2-interferon. This effect is retained at a temperature of 37 degrees C and increases when the chemical drug is combined with a mixture of alpha- and gamma-interferon.
D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D004686:Encephalomyocarditis virus / Q000187:drug effects*; D006801:Humans; D007372:Interferons / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D011994:Recombinant Proteins / Q000494:pharmacology; D012254:Ribavirin / Q000494:pharmacology*; D012263:Ribonucleosides / Q000494:pharmacology*; D013696:Temperature; D014616:Vaccinia virus / Q000187:drug effects*; D014776:Virus Cultivation
D011994:Recombinant Proteins; D012263:Ribonucleosides; D012254:Ribavirin; D007372:Interferons
Potentsirovanie antivirusnoĭ aktivnosti chelovecheskikh interferonov virazolom v opytakh in vitro.