[Comparison of the antigenic properties of the HMG proteins composing the chromatin of tissues differing in levels of transcription activity].
In experiments on tissues with a high level of transcription (liver, brain) and with blocked genome (amphibian erythrocytes), it has been shown that the accessibility of antigenic determinants of HMG14 and HMG17 proteins is decreased in a sequence: liver, brain, erythrocytes. No differences in interaction of antigenic determinants of HMG2 protein with corresponding antibodies were found in the chromatin of the tissues investigated. Complement binding was higher in the interaction of chromatin from the liver and brain with antisera to HMG14 and HMG17 proteins, than with antiserum to HMG2 protein. No differences in antigenic properties of the investigated fractions of HMG proteins were observed in the amphibian erythrocytes.
D000818:Animals; D000941:Antigens / Q000276:immunology*; D001921:Brain / Q000276:immunology; D002417:Cattle; D002843:Chromatin / Q000276:immunology*; D003168:Complement Fixation Tests; D000939:Epitopes / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology; D006609:High Mobility Group Proteins / Q000276:immunology*; D008099:Liver / Q000276:immunology; D011898:Ranidae; D051381:Rats; D014158:Transcription, Genetic
D000941:Antigens; D002843:Chromatin; D000939:Epitopes; D006609:High Mobility Group Proteins
Sravnenie antigennykh svoĭstv belkov HMG v sostave khromatina tkaneĭ razlichaiushchikhsia po urovniu transkriptsionnoĭ aktivnosti.