Morphology and functional characteristics of isolated porcine intraepithelial lymphocytes.
We have examined the morphology and functional characteristics of porcine intraepithelial lymphocytes (IEL). A subpopulation of IEL contains granules as seen in other species, and their ultrastructure was also similar. They were capable of producing T-cell growth factor and interferon on in vitro stimulation. IEL killed P815 cells in the presence of PHA, but did not kill K562 cells.
D000818:Animals; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D003602:Cytotoxicity, Immunologic; D004847:Epithelial Cells; D004848:Epithelium / Q000648:ultrastructure; D007372:Interferons / Q000096:biosynthesis; D007376:Interleukin-2 / Q000096:biosynthesis; D007694:Killer Cells, Natural / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology / Q000648:ultrastructure*; D008854:Microscopy, Electron; D013552:Swine
D007376:Interleukin-2; D007372:Interferons