[Synchronization of calcium channel activity in mollusk neurons after treatment with ferricyanide and barium ions].
Using the patch-voltage-clamp method on the isolated membrane patches from molluscan neurons, effects of ferricyanide and barium on fast potassium channels with a priori destroyed synchronism in the transitions between conductance sublevels were studied. Ferricyanide (0.1-0.5 mM) applied at the inner membrane side produced irreversible transformation of occasional transitions of the channel conductance between intermediate states into highly cooperative and potential-dependent process. Barium ions completely or partly reversibly restore synchronism.
D000818:Animals; D001464:Barium / Q000494:pharmacology*; D002118:Calcium / Q000378:metabolism*; D005292:Ferricyanides / Q000494:pharmacology*; D066298:In Vitro Techniques; D007473:Ion Channels / Q000187:drug effects*; D008195:Lymnaea; D008564:Membrane Potentials / Q000187:drug effects; D009474:Neurons / Q000378:metabolism / Q000502:physiology*
D005292:Ferricyanides; D007473:Ion Channels; C007931:hexacyanoferrate III; D001464:Barium; D002118:Calcium
Sinkhronizatsiia aktivnosti kalievykh kanalov neĭronov molliuska pod deĭstviem ferritsianida i ionov bariia.