title: Pyrolytic carbon, porous implants, and the fibrin adhesive system.
abstract: The bone implant interface for Pyrolite and titanium alloy was evaluated. The effects of a fibrin adhesive system (FAS) on the interface was also compared. Fixation of the Pyrolite and porous titanium implants was observed to occur in the 4-week period of the study with minimal fibrous tissue encapsulation. The ultimate interfascial shear strength for bone-Pyrolite interface was attained at 4 weeks. No adverse effect with utilization of the FAS could be identified. Further investigation into the use of Pyrolite and the FAS in foot surgery is anticipated.
mesh_terms: D000818:Animals; D007611:Aprotinin / Q000627:therapeutic use*; D001842:Bone and Bones / Q000473:pathology / Q000601:surgery*; D002244:Carbon; D004338:Drug Combinations / Q000627:therapeutic use; D005176:Factor XIII / Q000627:therapeutic use*; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen / Q000627:therapeutic use*; D019736:Prostheses and Implants; D011817:Rabbits; D013917:Thrombin / Q000627:therapeutic use*; D014014:Tissue Adhesives / Q000627:therapeutic use*; D014025:Titanium
chemical_list: D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives; C009139:pyrolytic carbon; D002244:Carbon; D005340:Fibrinogen; D005176:Factor XIII; D007611:Aprotinin; D014025:Titanium; D013917:Thrombin