title: [Primary cytostatic therapy of progressive squamous cell carcinoma of the oral cavity].
abstract: Reported on therapeutic study by 20 patients with inoperable carcinoma of the oral cavity. Primary we made a systemic antineoplastic chemotherapy with combination of methotrexate, bleomycine and vincristine. After the cytostatic therapy we lead through an operative revision or a radiological treatment. The patients live on an average 11.5 months. This is not longer than in the control-group with solitary radiological treatment. At present we cannot recommend the neoadjuvant chemotherapy of progressive squamous cell carcinomas of the oral cavity.
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000628:therapy; D003131:Combined Modality Therapy; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage; D009062:Mouth Neoplasms / Q000188:drug therapy* / Q000628:therapy; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D001761:Bleomycin; D014750:Vincristine; D008727:Methotrexate
vernacular_title: Primäre Zytostatikabehandlung ausgedehnter Plattenepithelkarzinome der Mundhöhle.