[Frequency distribution of DNA in blood and bone marrow cells of children with acute non-lymphatic leukemia using impulse cytophotometry].
1. As compared with the peripheral blood lymphocytes of healthy subjects the cells in the mononuclear fraction of peripheral blood and in the bone marrow of children with ANLL show a significant higher S- and G2 + M-phase. 2. A high proliferative activity correlate with a bad prognosis or with reaching no haematological remission. 3. Frequently, aneuploid cell populations will occur in the morphological subtypes M 4 and M 5.
D000208:Acute Disease; D000293:Adolescent; D000782:Aneuploidy; D001853:Bone Marrow / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D003592:Cytophotometry; D004273:DNA, Neoplasm / Q000378:metabolism*; D005260:Female; D006801:Humans; D007399:Interphase; D007938:Leukemia / Q000473:pathology*; D007945:Leukemia, Lymphoid / Q000473:pathology; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D011379:Prognosis
D004273:DNA, Neoplasm
Untersuchungen der DNS-Häufigkeitsverteilung in Blut- und Knochenmarkzellen von Kindern mit akuter nichtlymphatischer Leukämie mittels Impulszytophotometrie.