Primary germinoma of the brain. Immunocytochemical demonstration of tumour cells in the cerebrospinal fluid.
A patient is presented, who developed a suprasellar tumour. Stereotactical biopsy of the tumour revealed the diagnosis of a dysgerminoma. Immunocytochemical examination of the CSF showed neoplastic cells staining for human chorionic gonadotropin and for alpha-fetoprotein. The authors stress the possibility to diagnose primary intracranial germ cell tumours without operation.
D000293:Adolescent; D002551:Cerebral Ventricle Neoplasms / Q000134:cerebrospinal fluid* / Q000175:diagnosis; D002555:Cerebrospinal Fluid / Q000166:cytology; D006063:Chorionic Gonadotropin / Q000134:cerebrospinal fluid; D004407:Dysgerminoma / Q000134:cerebrospinal fluid* / Q000175:diagnosis; D006651:Histocytochemistry; D006801:Humans; D007158:Immunologic Techniques; D008297:Male; D000509:alpha-Fetoproteins / Q000134:cerebrospinal fluid
D006063:Chorionic Gonadotropin; D000509:alpha-Fetoproteins