title: Solid facial edema as a complication of acne vulgaris: treatment with isotretinoin and clofazimine.
abstract: We present two patients, a 20-year-old female and an 18-year-old male, who suffered from persistent solid facial edema as a complication of acne vulgaris. They were treated with isotretinoin with moderate response and thereafter with lymph massage with further response. The female patient also received clofazimine with good response.
mesh_terms: D000152:Acne Vulgaris / Q000150:complications*; D000293:Adolescent; D000328:Adult; D002991:Clofazimine / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000627:therapeutic use; D004487:Edema / Q000188:drug therapy / Q000209:etiology*; D005145:Face; D005260:Female; D006801:Humans; D015474:Isotretinoin; D008297:Male; D014212:Tretinoin / Q000627:therapeutic use*
chemical_list: D003879:Dermatologic Agents; D014212:Tretinoin; D002991:Clofazimine; D015474:Isotretinoin