Increased tubulin messenger RNA in the frog retina after optic nerve transection.
The optic nerve of the bullfrog (Rana catesbeiana) was transected and the regeneration process was investigated. The nerve regeneration was confirmed by observing the extension of the axon and by examining the recovery of axonal transport. Following optic nerve transection, the rapid and transient increase of messenger RNA of alpha-tubulin gene was observed in the retina, but no specific change of actin messenger RNA was observed.
D000818:Animals; D001370:Axonal Transport; D001369:Axons / Q000378:metabolism / Q000502:physiology; D005786:Gene Expression Regulation; D009416:Nerve Regeneration; D009900:Optic Nerve / Q000502:physiology; D012333:RNA, Messenger / Q000378:metabolism*; D011892:Rana catesbeiana; D012160:Retina / Q000378:metabolism* / Q000502:physiology; D014404:Tubulin / Q000378:metabolism* / Q000502:physiology
D012333:RNA, Messenger; D014404:Tubulin