title: Measurement of right ventricular blood temperature during exercise as a means of rate control in physiological pacemakers.
abstract: Several biological parameters have been suggested for rate control in physiological pacemakers in the past. Up to now, measurements of central venous blood temperature have been mostly done on dogs. We studied central venous blood temperature and heart rate in 14 healthy volunteers under conditions of treadmill and bicycle exercise with different workloads. A custom-made 5F lead with a thermistor incorporated near the tip was placed at the right ventricle under fluoroscopic control. Temperature was recorded with an accuracy of 1/100 degrees C on a digital memory device at a sampling rate of 5-10 s. We found the increase in blood temperature to be not only a function of absolute workloads but also a function of the individual's maximum exercise tolerance. Independent of the absolute increase in heart rate and temperature at a given workload, the individual's relation of increase in temperature and heart rate was found to be highly correlating (r = 0.9095). At a load of 100 W, we found a mean increase in heart rate of 52 beats and of temperature of 0.57 degree C, at 150 W of 74 beats/min and 0.84 degree C. During, as well as after, the exercise, heart rate and temperature have a parallel course. According to our data, control of physiological pacemakers by means of central venous blood temperature is possible.
mesh_terms: D001769:Blood; D006339:Heart Rate; D006801:Humans; D010138:Pacemaker, Artificial; D005082:Physical Exertion; D013696:Temperature