Water goitrogens and endemic goitre in the Sudan.
The main cause of endemic goitre in the Sudan is dietary iodine deficiency. Water samples from four areas [Kass, Kosti, Wad Medani and Omdurman] two of which are known for endemic goitre did not appear to have any goitrogenic effect in our preliminary experiment using porcine thyroid follicle cell preparations.
D000818:Animals; D013956:Antithyroid Agents / Q000032:analysis*; D002478:Cells, Cultured; D004032:Diet; D006043:Goiter, Endemic / Q000209:etiology*; D006801:Humans; D007455:Iodine / Q000172:deficiency; D013397:Sudan; D013552:Swine; D013961:Thyroid Gland / Q000166:cytology; D014881:Water Supply / Q000032:analysis*
D013956:Antithyroid Agents; D007455:Iodine