The characteristics of the HLA antigens determined by cellular techniques.
The complexity of the D region of the HLA complex is rather great. Three loci--HLA-DP, DQ, DR are very well established in this time. However, the question about the independence of the first known locus of this region--HLA-D--remains elusive--it is still not known if HLA-D antigens are really independent or they rather represent some epitopes of HLA-DR/DQ antigens. The HLA-DP antigens represent the additional series of specificities of the HLA complex recognized by PLT technique. On the other hand HLA-PL antigens, detected by PLT too, correlate as to HLA-D as to HLA-DR antigens and with a great probability they do not form an independent group of HLA antigens.
D000911:Antibodies, Monoclonal; D002874:Chromosome Mapping; D000939:Epitopes / Q000276:immunology; D006680:HLA Antigens / Q000032:analysis / Q000145:classification / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D006682:HLA-DP Antigens; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II / Q000032:analysis / Q000235:genetics; D006801:Humans; D007959:Lymphocyte Culture Test, Mixed / Q000379:methods; D008214:Lymphocytes / Q000276:immunology; D008285:Major Histocompatibility Complex; D008722:Methods
D000911:Antibodies, Monoclonal; D000939:Epitopes; D006680:HLA Antigens; D006682:HLA-DP Antigens; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II