Ovarian dysgerminoma: immunocytochemical localization of human chorionic gonadotropin in the germinoma cell cytoplasm.
A case of a pure ovarian dysgerminoma is reported in which the tumor was devoid of syncytiotrophoblastic giant cells, yet it produced human chorionic gonadotropin (hCG). Immunocytochemical studies localized the hCG in the germinoma cell cytoplasm, suggesting that these cells were the site of production.
D000293:Adolescent; D006063:Chorionic Gonadotropin / Q000032:analysis* / Q000097:blood; D018997:Chorionic Gonadotropin, beta Subunit, Human; D003593:Cytoplasm / Q000032:analysis; D004407:Dysgerminoma / Q000032:analysis* / Q000473:pathology; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007124:Immunoenzyme Techniques; D010051:Ovarian Neoplasms / Q000032:analysis* / Q000473:pathology; D010446:Peptide Fragments / Q000097:blood
D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D010446:Peptide Fragments