Circadian rhythm and seasonal variations in basal cAMP content of rat heart ventricles.
The cAMP content in rat heart ventricles was studied at 3-hr intervals during 24hr at different times of the year. A significant circadian rhythm in cAMP content was found. Time of the year reproducibly influenced the 24-hr mean, the amplitude as well as the peak value in cAMP in relation to circadian time.
D015056:1-Methyl-3-isobutylxanthine / Q000494:pharmacology; D000818:Animals; D002940:Circadian Rhythm; D000242:Cyclic AMP / Q000378:metabolism*; D006352:Heart Ventricles / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012621:Seasons; D016276:Ventricular Function
D000242:Cyclic AMP; D015056:1-Methyl-3-isobutylxanthine