[Methodologic aspects of measuring the potential differences in the gastrointestinal tract: effect of electrode placement and electrolyte concentration of the measuring electrode on the magnitude of the transepithelial potential difference].
The transepithelial electric potential difference (tPD) of the colonic mucosa was investigated in children in-vivo. The potential difference was measured by so-called "flowing"-electrodes. The current paper presents methodical considerations, for instance electrolyte concentration of the luminal electrode and position of the serosal electrode (reference-electrode), and their influence on the tPD-measurement.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004566:Electrodes; D004573:Electrolytes / Q000378:metabolism*; D004848:Epithelium / Q000502:physiology; D006801:Humans; D007413:Intestinal Mucosa / Q000502:physiology*; D007473:Ion Channels / Q000502:physiology*; D008564:Membrane Potentials; D012016:Reference Values
D004573:Electrolytes; D007473:Ion Channels
Methodische Aspekte der Potentialdifferenzmessung im Gastrointestinaltrakt: Einfluss der Elektrodenplazierung und Elektrolytkonzentration der Messelektrode auf die Grösse der transepithelialen Potentialdifferenz (tPD).