[Endocrine tumors of the hepatobiliary system. Case report and review of the literature].
Immunohistochemical findings are reported from an endocrinologically active tumor of the liver hilus in a 39 year old woman. Clinical findings were dominated by difficult to control hypokalemia, cholelithiasis and mild hypoglycemia. Immunohistochemical studies demonstrated somatostatin, beta-HCG and neuron-specific enolase in the tumor cells. No further tumor was found at autopsy. Review of the literature relating to the previously reported tumors of the hepatobiliary system demonstrates great variability in these neoplasms with respect to histologic structure, staining characteristics, ultrastructure, results of immunohistochemical studies and clinical manifestations.
D000328:Adult; D001650:Bile Duct Neoplasms / Q000032:analysis / Q000378:metabolism / Q000473:pathology*; D006063:Chorionic Gonadotropin / Q000032:analysis; D018997:Chorionic Gonadotropin, beta Subunit, Human; D005260:Female; D006729:Hormones, Ectopic / Q000032:analysis*; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000032:analysis / Q000378:metabolism / Q000473:pathology*; D008854:Microscopy, Electron; D010446:Peptide Fragments / Q000032:analysis; D010751:Phosphopyruvate Hydratase / Q000378:metabolism; D013004:Somatostatin / Q000032:analysis
D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D006729:Hormones, Ectopic; D010446:Peptide Fragments; D013004:Somatostatin; D010751:Phosphopyruvate Hydratase
Endokrine Tumoren des hepatobiliären Systems. Fallbericht und Literaturübersicht.