title: [Isolation of non-type-specific protein antigens of Streptococcus group B].
abstract: Hydrochloride extracts obtained from group B streptococcal strains of different serotypes have proved to be the source of type-nonspecific protein antigens, precipitated with ethanol and studied by gel chromatography and spectrophotometric scanning in ultraviolet rays. Thus, 2 or 3 antigens, one of them found to be common for streptococci of groups A, B and G, as well as the admixture of group-specific polysaccharide, have been detected. In extracts obtained from group B streptococcal strains of different serotypes a common protein antigen, specific only for group B, has been detected. The suitability of gel chromatography with the use Toyopearl gel HW-55F for the preparative isolation of the specific fraction of protein type-nonspecific antigen with a view to the subsequent study of immune response to group B streptococci has been shown.
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis / Q000302:isolation & purification*; D001426:Bacterial Proteins / Q000032:analysis / Q000276:immunology / Q000302:isolation & purification*; D002850:Chromatography, Gel / Q000379:methods; D000939:Epitopes / Q000032:analysis / Q000302:isolation & purification*; D007114:Immunization; D011817:Rabbits; D012703:Serotyping; D013056:Spectrophotometry, Ultraviolet; D013292:Streptococcus agalactiae / Q000145:classification / Q000276:immunology*
chemical_list: D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D000939:Epitopes
vernacular_title: Poluchenie netipospetsificheskikh belkovykh antigenov streptokokka gruppy B.