Immunological studies in chronic mucocutaneous candidiasis before and after ketoconazole treatment.
Immune functions were studied in eight patients with chronic mucocutaneous candidiasis representing a broad clinical spectrum of this disease. Clinical improvement after ketoconazole for 6 months was not associated with amelioration of cutaneous delayed hypersensitivity to Candida antigen or the in vitro lymphocyte responses to Candida antigen of T-cell mitogens.
D000293:Adolescent; D000328:Adult; D000936:Antigen-Antibody Complex / Q000378:metabolism; D002177:Candidiasis / Q000276:immunology*; D002178:Candidiasis, Chronic Mucocutaneous / Q000188:drug therapy / Q000276:immunology*; D002648:Child; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D007654:Ketoconazole / Q000627:therapeutic use*; D008213:Lymphocyte Activation; D008297:Male; D008875:Middle Aged; D012882:Skin Tests
D000936:Antigen-Antibody Complex; D007654:Ketoconazole