Delayed tissue necrosis due to mitomycin C.
We report about a patient having received intravenous mitomycin C without evidence of tissue injury until three months following its extravasation. After drinking alcoholic beverages 3 months later he developed a severe ulcer at the site of the previous extravasation. There are only a few reports about such extravasation ulcers occurring a long time after the injection.
D006801:Humans; D008297:Male; D008875:Middle Aged; D016685:Mitomycin; D008937:Mitomycins / Q000009:adverse effects*; D009336:Necrosis; D012883:Skin Ulcer / Q000139:chemically induced* / Q000473:pathology
D008937:Mitomycins; D016685:Mitomycin