[Treatment of 2 newborn infants with autoimmune thrombocytopenia by high-dose intravenous gamma globulins].
We report 2 cases of neonatal auto-immune thrombocytopenia treated with high-dose intravenous gamma-globulins. Efficacy of treatment was immediate, inducing an increase in platelet levels which was transitory during the first 2 weeks but stabilized in the third week. Tolerance was excellent. Injections of 400 mg/kg/day repeated for 4 to 5 days should be preferred to a single dose of 1 to 2 g/kg.
D000328:Adult; D001323:Autoantibodies / Q000032:analysis; D001327:Autoimmune Diseases / Q000151:congenital / Q000628:therapy*; D001792:Blood Platelets / Q000276:immunology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007275:Injections, Intravenous; D008297:Male; D008431:Maternal-Fetal Exchange; D010976:Platelet Count; D011247:Pregnancy; D013921:Thrombocytopenia / Q000151:congenital / Q000628:therapy*; D005719:gamma-Globulins / Q000008:administration & dosage*
D001323:Autoantibodies; D005719:gamma-Globulins
Traitement de deux nouveau-nés atteints de thrombocytopénies auto-immunes par les gammaglobulines intraveineuses à fortes doses.