Gramicidin A--phospholipid model systems.
Gramicidin A forms ion-conducting channels which can traverse the hydrocarbon core of lipid bilayer membranes. The structures formed by gramicidin A are among the best characterized of all membrane-bound polypeptides or proteins. In this review a brief summary is given of the occurrence, conformation, and synthesis of gramicidin A, and of its use as a model for ion transport and the interaction of proteins and lipids in biological membranes.
D006096:Gramicidin; D007473:Ion Channels / Q000502:physiology*; D008051:Lipid Bilayers; D008823:Micelles; D008954:Models, Biological; D010743:Phospholipids
D007473:Ion Channels; D008051:Lipid Bilayers; D008823:Micelles; D010743:Phospholipids; D006096:Gramicidin