The dose response of granulocyte-macrophage colony stimulating activity (GM-CSA) for sera of "Swiss" mice after endotoxin "lipopolysaccharide B" Escherichia coli (0127: B8) intraperitoneal administration.
The effect of different doses of endotoxin (Lipopolysaccharide B) on Granulocyte-Macrophage Colony Stimulating Activity (GM-CSA) in the sera of "Swiss" male mice was measured by granulocyte-macrophage "in vitro" colony formation. The highest GM-CSA was found to be present 3-4 hours after 200 micrograms of endotoxin intraperitoneal injection.
D000818:Animals; D003114:Colony-Forming Units Assay; D004305:Dose-Response Relationship, Drug; D004731:Endotoxins / Q000008:administration & dosage*; D004926:Escherichia coli; D007274:Injections, Intraperitoneal; D007377:Interleukin-3 / Q000032:analysis*; D008070:Lipopolysaccharides / Q000008:administration & dosage*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains
D004731:Endotoxins; D007377:Interleukin-3; D008070:Lipopolysaccharides; C036757:lipopolysaccharide B