[Antibody response to capsular polysaccharide antigen in an infection caused by meningococcus serogroup B in children].
The continuous synchronous cultivation of serogroup B meningococci and the use of the selected clones of producer strains has made it possible to obtain the serologically active preparation of the group-specific antigen from the culture in the exponential phase. The erythrocyte diagnosticum produced on the basis of this preparation has permitted the detection of group-specific antibodies in the sera of immunized rabbits and children with generalized infection caused by serogroup B meningococci. The intensity of immune response depends on the age of children. This new technique of the passive hemagglutination test is recommended for the confirmation of generalized infection caused by serogroup B meningococci.
D000907:Antibodies, Bacterial / Q000032:analysis; D000937:Antigen-Antibody Reactions; D000942:Antigens, Bacterial / Q000276:immunology*; D002648:Child; D000939:Epitopes / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology; D006386:Hemagglutination Tests / Q000379:methods; D006801:Humans; D008589:Meningococcal Infections / Q000175:diagnosis / Q000276:immunology*; D009345:Neisseria meningitidis / Q000276:immunology*; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D013997:Time Factors
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D000939:Epitopes; D011135:Polysaccharides, Bacterial
Antitel'nyĭ otvet na kapsul'nyĭ polisakharidnyĭ antigen pri infektsii, vyzvannoĭ meningokokkami serogruppy B, u deteĭ.