"No suture" microanastomosis using Vicryl rings and fibrin adhesive system: an unsuccessful attempt.
Vascular repairs using a combination of Vicryl rings to evert vessel edges and the Tisseel two-component fibrin adhesive system failed to achieve patent microanastomosis without using stay sutures. The bonding force of Tisseel alone was not sufficient to hold the cut ends of rat femoral arteries and veins together. All 10 arterial and 8 venous end-to-end anastomoses separated under normal intraluminal pressure immediately after the removal of microclamps. This method was found to be an unacceptable alternative to the conventional suturing method.
D000818:Animals; D007611:Aprotinin; D002122:Calcium Chloride; D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen; D011098:Polyglactin 910; D011108:Polymers; D051381:Rats; D011919:Rats, Inbred Strains; D013529:Surgical Wound Dehiscence / Q000209:etiology*; D013536:Suture Techniques; D013917:Thrombin; D014656:Vascular Surgical Procedures / Q000379:methods*
D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D011108:Polymers; D011098:Polyglactin 910; D005340:Fibrinogen; D007611:Aprotinin; D013917:Thrombin; D002122:Calcium Chloride