title: [Initial experiences with interstitial brachycurietherapy (low dose rate I-125 seeds in carrier/vicryl and high dose rate Ir-192 afterloading system) in the palliative treatment of head and neck tumors].
abstract: The local control rates for previously irradiated recurrent tumours of the head and neck is dose dependent. High dose percutaneous irradiation alone is associated with a high complication rate. On the other hand it is possible to apply high local doses by interstitial irradiation, whilst sparing the surrounding tissue. In the last 2 years we have used Iodine 125-seeds in carrier (Vicryl) and a high dose rate Iridium 192-source for the afterloading technique. Our first experiences with 12 patients show reasonable palliation, but not effect on survival.
mesh_terms: D001918:Brachytherapy / Q000379:methods*; D006258:Head and Neck Neoplasms / Q000532:radiotherapy*; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D007495:Iridium / Q000627:therapeutic use; D008207:Lymphatic Metastasis; D009364:Neoplasm Recurrence, Local / Q000532:radiotherapy; D010166:Palliative Care; D011868:Radioisotopes / Q000627:therapeutic use; D011879:Radiotherapy Dosage
chemical_list: D007457:Iodine Radioisotopes; D011868:Radioisotopes; D007495:Iridium
vernacular_title: Erste Erfahrungen mit interstitieller Brachycurietherapie (low-dose-rate J-125-seeds in carrier/Vicryl bzw. high-dose-rate Ir-192-afterloading system) in der Palliativbehandlung von Kopf-Hals-Tumoren.