Macrophages and mast cells in chronic cholecystitis and "normal" gall bladders.
An attempt was made to quantify mast cells using toluidine blue and macrophages, with alpha-1-antitrypsin as a marker, from adjacent sections in the mucosa of two groups of gall bladders showing either minimal inflammatory change or established chronic cholecystitis. The results were expressed as cells/mm2 of mucosa. Alpha-1-antitrypsin showed both macrophages and mast cells, and therefore an estimate of macrophage numbers was obtained by subtraction. Mast cells comprised more than 60% of the alpha-1-antitrypsin positive cells. There were significantly (p greater than 0.001) more mast cells and macrophages in minimal inflammatory gall bladder mucosa than in established chronic cholecystitis.
D002452:Cell Count; D002764:Cholecystitis / Q000473:pathology*; D005704:Gallbladder / Q000473:pathology*; D006801:Humans; D008264:Macrophages / Q000473:pathology*; D008407:Mast Cells / Q000473:pathology*; D009092:Mucous Membrane / Q000473:pathology; D013194:Staining and Labeling; D014048:Tolonium Chloride; D000515:alpha 1-Antitrypsin
D000515:alpha 1-Antitrypsin; D014048:Tolonium Chloride