title: Human Schwann cells: cytochemical, ultrastructural and immunological studies in vivo and in vitro.
abstract: Cytochemical, ultrastructural and immunological properties of human Schwann cells were studied in normal adult and foetal nerve sections and in tissue cultures. As specific markers for Schwann cells we used S-100 protein and laminin. The presence of Sudan black-positive, Oil Red-O-negative material was found in Schwann cells in vitro. Structural features, examined at E.M. level, are described. This information may be useful in nerve tissue culture studies, a new tool for the investigation of dyschwannian neuropathies.
mesh_terms: D002478:Cells, Cultured; D006651:Histocytochemistry; D006801:Humans; D007158:Immunologic Techniques; D007797:Laminin / Q000378:metabolism; D008854:Microscopy, Electron; D009418:S100 Proteins / Q000378:metabolism; D012583:Schwann Cells / Q000166:cytology* / Q000276:immunology / Q000378:metabolism; D013194:Staining and Labeling
chemical_list: D007797:Laminin; D009418:S100 Proteins