title: [Diagnosis and treatment of the toxic syndrome in diffuse peritonitis].
abstract: Based on an analysis of clinico-laboratory manifestations of intoxication in 202 patients with widespread forms of peritonitis the authors give a classification of severity of the intoxication syndrome. The role of proteases and middle size peptides in pathogenesis of endogenous intoxication in peritonitis is shown. The irrigation of the abdominal cavity with Kontrical is recommended in the postoperative period for decreasing the intoxication. Hemosorption was also used in patients with the growing syndrome of endogenous III degree intoxication. The methods used lowered lethality from 29.9% to 17.8%.
mesh_terms: D007611:Aprotinin / Q000627:therapeutic use; D001202:Ascitic Fluid / Q000201:enzymology; D006464:Hemoperfusion; D006801:Humans; D010447:Peptide Hydrolases / Q000378:metabolism; D010455:Peptides / Q000097:blood; D010538:Peritonitis / Q000175:diagnosis* / Q000628:therapy; D007507:Therapeutic Irrigation; D014115:Toxemia / Q000175:diagnosis* / Q000628:therapy
chemical_list: D010455:Peptides; D007611:Aprotinin; D010447:Peptide Hydrolases
vernacular_title: Diagnostik i lechenie intoksikatsionnogo sindroma pri razlitom peritonite.