[Changes in the serum fraction composition of nucleic acids in radiation injuries. Alterations in an early period after gamma-irradiation of rats].
The content and fractional composition of nucleic acids of blood serum change after lethal (8 Gy) particularly superlethal (100 Gy) gamma-irradiation of rats. This concerns DNA the content of which increases by 7 times 5 h following 100 Gy irradiation. It has been shown by electrophoresis in 0.85% agarose that a heterogeneous DNA fraction with the molecular weight of (1-15) X 10(6) dalton increases. The analysis of the preparation in the polyacrylamide gel has revealed a DNA fraction that is not found in norm: the fraction possesses the electrophoretic mobility corresponding to that of nucleosome DNA.
D000818:Animals; D005591:Chemical Fractionation; D004247:DNA / Q000097:blood* / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D004587:Electrophoresis, Agar Gel; D004591:Electrophoresis, Polyacrylamide Gel; D008297:Male; D008970:Molecular Weight; D012313:RNA / Q000097:blood* / Q000528:radiation effects; D011833:Radiation Injuries, Experimental / Q000097:blood*; D051381:Rats; D013997:Time Factors
D012313:RNA; D004247:DNA
Izmeneniia fraktsionnogo sostava nukleinovykh kislot syvorotki krovi pri radiatsionnykh porazheniiakh. Narusheniia v rannie sroki posle gamma-oblucheniia krys.