title: Clinical investigations on long-term activation of fibrinolysis by anabolic steroids.
abstract: The influence of anabolic steroids plus phenformin on the course of disease was studied in patients suffering from occlusive vascular diseases. In arteriosclerosis obliterans of the lower limbs the combined therapy led to a higher percentage of improvement than the control group showed. In coronary heart disease there was also a beneficial effect of this treatment. The drugs were found to exert beneficial clinical effects especially in patients with thrombophlebitis migrans and superficial thrombophlebitis. From the results of this study it is concluded that this therapy may be of clinical value in the treatment of patients with occlusive vascular diseases.
mesh_terms: D000328:Adult; D000368:Aged; D001162:Arteriosclerosis Obliterans / Q000097:blood* / Q000188:drug therapy; D002986:Clinical Trials as Topic; D003327:Coronary Disease / Q000097:blood* / Q000188:drug therapy; D005260:Female; D005342:Fibrinolysis / Q000187:drug effects*; D006801:Humans; D008297:Male; D008696:Methandrostenolone / Q000494:pharmacology / Q000627:therapeutic use*; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000150:complications / Q000188:drug therapy; D010629:Phenformin / Q000494:pharmacology / Q000627:therapeutic use*; D013197:Stanozolol / Q000494:pharmacology / Q000627:therapeutic use*; D013924:Thrombophlebitis / Q000097:blood* / Q000188:drug therapy / Q000209:etiology; D014648:Varicose Veins / Q000097:blood / Q000150:complications / Q000188:drug therapy
chemical_list: D013197:Stanozolol; D008696:Methandrostenolone; D010629:Phenformin