Language and memory disturbances from mesencephalothalamic infarcts. A clinical and computed tomography study.
Three right-handed subjects presented impairment of consciousness, paralysis of vertical gaze, aphasia and memory disturbances. Computed tomography scans showed low-density lesions in the paramedian areas of the left thalamus. Neuropsychological examination revealed a fluent aphasia in one patient and a nonfluent in two; all had paraphasias and perseveration. Comprehension, repetition and writing were normal. In the literature on so-called thalamic aphasia only a few cases are reported with involvement of the paramedian nuclear complex.
D000328:Adult; D000368:Aged; D000849:Anomia / Q000473:pathology; D001037:Aphasia / Q000473:pathology*; D002544:Cerebral Infarction / Q000473:pathology*; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011939:Mental Recall / Q000502:physiology; D008636:Mesencephalon / Q000473:pathology*; D008875:Middle Aged; D009483:Neuropsychological Tests; D013786:Thalamic Diseases / Q000473:pathology*; D013788:Thalamus / Q000473:pathology; D014057:Tomography, X-Ray Computed