title: Sequential chemotherapy with methotrexate and 5-fluorouracil: mechanism of synergistic effect.
mesh_terms: D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage; D009369:Neoplasms / Q000188:drug therapy* / Q000378:metabolism; D011687:Purines / Q000096:biosynthesis; D012313:RNA / Q000378:metabolism
chemical_list: D011687:Purines; D012313:RNA; D005472:Fluorouracil; D008727:Methotrexate