RNA synthesis in guinea pig peripheral blood lymphocytes and heterophils during sensitization.
The synthesis of RNA in guinea pig leukocytes was investigated during sensitization by the use of tritiated uridine. The increase of the number of RNA-synthetizing heterophils was found in 21st day of sensitization. That was connected with morphological features of heterophils nuclei. Among lymphocytes in 11th day of sensitization the subpopulation of cells intensively synthetizing RNA was observed. The possible role of cells, which synthetize RNA in the process of sensitization is discussed.
D000818:Animals; D006168:Guinea Pigs; D008214:Lymphocytes / Q000378:metabolism*; D008297:Male; D009504:Neutrophils / Q000378:metabolism*; D010047:Ovalbumin; D012313:RNA / Q000096:biosynthesis*; D014316:Tritium; D014529:Uridine / Q000378:metabolism
D014316:Tritium; D012313:RNA; D010047:Ovalbumin; D014529:Uridine