Renographic comparison of function in bivalved kidneys repaired using either a fibrin adhesive (Tisseel) or conventional suturing.
In 6 male baboons, the left kidney was bivalved and repaired using a fibrin adhesive (group A) or conventional suturing (group B). 99mTc diethylenetriamine penta-acetic acid (DTPA) renography was used to evaluate renal function for up to 24 weeks after surgery. No significant impairment of renal function could be detected for either of the two repair methods. It seems as though the function was less affected after suturing, but the trend could not be supported statistically. The fibrin adhesive did not prove superior to conventional suturing.
D000818:Animals; D007611:Aprotinin; D004338:Drug Combinations; D005176:Factor XIII; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen; D007668:Kidney / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D010215:Papio; D011866:Radioisotope Renography; D013536:Suture Techniques; D013917:Thrombin; D014014:Tissue Adhesives
D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives; D005340:Fibrinogen; D005176:Factor XIII; D007611:Aprotinin; D013917:Thrombin