Distribution of capsaicin-sensitive urinary bladder afferents in the rat spinal cord.
The capsaicin-sensitive afferent innervation of the urinary bladder and the central nervous system distribution of urinary bladder afferents have been studied in the rat. Capsaicin-sensitive primary sensory neurones supplying the urinary bladder have been found in two groups of spinal ganglia located in the Th13-L2 and L6-S1 segments. Capsaicin-sensitive primary sensory afferents from the bladder terminate within Rexed's laminae I, V and X, and in the dorsal gray commissure of the lumbosacral spinal cord. In addition, the results point to a possible vagal sensory innervation of the urinary bladder.
D000344:Afferent Pathways / Q000033:anatomy & histology / Q000166:cytology; D000818:Animals; D002211:Capsaicin / Q000494:pharmacology*; D005727:Ganglia, Spinal / Q000033:anatomy & histology / Q000166:cytology; D006735:Horseradish Peroxidase; D008297:Male; D009410:Nerve Degeneration / Q000187:drug effects; D009475:Neurons, Afferent / Q000145:classification / Q000166:cytology* / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D013116:Spinal Cord / Q000033:anatomy & histology* / Q000166:cytology; D001743:Urinary Bladder / Q000294:innervation*; D018998:Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; D014909:Wheat Germ Agglutinins
D018998:Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; D014909:Wheat Germ Agglutinins; D006735:Horseradish Peroxidase; D002211:Capsaicin