title: The syndrome of unilateral tuberothalamic artery territory infarction.
abstract: The study of 3 personal cases and 5 published cases of unilateral infarct limited to the territory of the tuberothalamic artery suggests that this syndrome should be differentiated from the other thalamic syndromes. The onset is usually sudden, with moderate contralateral weakness. Sensory changes may be present but remain mild. The patients are apathetic, show perseveration and may be disoriented. In left-sided infarcts, transcortical aphasia, verbal and visual memory impairment and sometimes acalculia are found. In right-sided infarcts, hemispatial neglect, visual memory impairment and disturbed visuospatial processing are common. A decreased level of consciousness, disturbed ocular movements, severe motor weakness and delayed abnormal movements do not occur. Involvement of the ventral lateral and dorsomedial nucleus with sparing of the intralaminar nuclei, posterolateral formation and upper midbrain may explain this picture. The fact that the tuberothalamic artery arises from the posterior communicating artery, which often receives its supply from the carotid system, further justifies considering unilateral tuberothalamic infarcts as a syndrome.
mesh_terms: D000208:Acute Disease; D000368:Aged; D001037:Aphasia / Q000503:physiopathology; D002544:Cerebral Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000523:psychology; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000503:physiopathology; D008875:Middle Aged; D009483:Neuropsychological Tests; D013577:Syndrome; D013786:Thalamic Diseases / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000523:psychology; D013788:Thalamus / Q000098:blood supply* / Q000503:physiopathology; D014057:Tomography, X-Ray Computed