[Inhibition of the depressive action of cyclophosphane on immunity and hematopoiesis].
Experiments demonstrated sodium nucleinate treatment to inhibit the cytotoxic and immunosuppressive effect of cyclophosphamide. This is an effective treatment for hemopoietic disturbances induced by cyclophosphamide.
D000276:Adjuvants, Immunologic / Q000494:pharmacology; D000818:Animals; D003520:Cyclophosphamide / Q000037:antagonists & inhibitors* / Q000633:toxicity; D004247:DNA / Q000032:analysis; D004305:Dose-Response Relationship, Drug; D006410:Hematopoiesis / Q000187:drug effects*; D007109:Immunity / Q000187:drug effects*; D007113:Immunity, Innate / Q000187:drug effects; D051379:Mice; D009696:Nucleic Acids / Q000494:pharmacology; D012313:RNA / Q000032:analysis; D012331:RNA, Fungal / Q000494:pharmacology; D012481:Salmonella Infections, Animal / Q000276:immunology; D012486:Salmonella typhimurium; D013154:Spleen / Q000032:analysis; D013997:Time Factors
D000276:Adjuvants, Immunologic; D009696:Nucleic Acids; D012331:RNA, Fungal; D012313:RNA; D003520:Cyclophosphamide; D004247:DNA; C013683:sodium nucleinate
Tormozhenie depressivnogo deĭstviia tsiklofosfana na immunitet i krovetvorenie.