Lysozyme activity of cystic mucosal and submucosal glands in the stomal area of the gastric remnant.
In order to study the lysozyme activity in the cystic mucosal and submucosal glands in the stomal area of the gastric remnant, which is one of the components of gastritis cystica polyposa, we carried out a pathological and immunohistochemical examination of 55 patients with gastric remnants, including 19 with stomal carcinoma, after partial gastrectomy for benign gastro-duodenal diseases. These stomach specimens were examined immunohistochemically for lysozyme. The cytoplasm of some epithelial cells of cystic mucosal and submucosal glands, which showed characteristic changes in the gastro-intestinal stoma as well as background changes in the stomal carcinoma, showed a strongly positive reaction for lysozyme. These strongly lysozyme-positive cells in the cystic mucosal glands appeared more frequently in the cases of stomal carcinoma than in the non-cancerous controls.
D000368:Aged; D004848:Epithelium / Q000201:enzymology; D005260:Female; D005743:Gastrectomy; D005753:Gastric Mucosa / Q000201:enzymology*; D005774:Gastrostomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009113:Muramidase / Q000378:metabolism*; D011379:Prognosis; D013194:Staining and Labeling; D013274:Stomach Neoplasms / Q000201:enzymology* / Q000601:surgery
D009113:Muramidase