On the transmitter at the A-to-B cell in Aplysia californica.
Cerebral A neurons make excitatory contact with cerebral B cells. While glutamate, histamine and serotonin all have excitatory receptors on B cells, the A-to-B cells synaptic potential was not found sensitive to curare, strychnine, antihistaminergic or antiserotoninergic drugs, nor did bath-perfused glutamate or serotonin cause desensitization of the synaptic response. We conclude that none of these candidates is the transmitter at this synapse.
D000818:Animals; D001048:Aplysia; D005724:Ganglia / Q000166:cytology / Q000187:drug effects* / Q000502:physiology; D005971:Glutamates / Q000502:physiology; D018698:Glutamic Acid; D006632:Histamine / Q000502:physiology; D066298:In Vitro Techniques; D007473:Ion Channels / Q000187:drug effects*; D018377:Neurotransmitter Agents / Q000494:pharmacology* / Q000502:physiology; D012701:Serotonin / Q000502:physiology; D009435:Synaptic Transmission / Q000187:drug effects*
D005971:Glutamates; D007473:Ion Channels; D018377:Neurotransmitter Agents; D012701:Serotonin; D018698:Glutamic Acid; D006632:Histamine