Identification of Babesia bigemina and Babesia bovis merozoite proteins with isolate- and species-common epitopes recognized by antibodies in bovine immune sera.
Immunoprecipitation of radiolabeled antigens with bovine antisera indicated that many Babesia bigemina and Babesia bovis merozoite proteins contain isolate-common epitopes, while at least 16 B. bigemina and 8 B. bovis proteins contain species-cross-reactive epitopes. One immunogenic, isolate-common, and species-specific candidate diagnostic protein from each species was identified.
D000818:Animals; D000907:Antibodies, Bacterial; D000937:Antigen-Antibody Reactions; D000953:Antigens, Protozoan / Q000276:immunology / Q000302:isolation & purification*; D001403:Babesia / Q000276:immunology* / Q000302:isolation & purification; D001404:Babesiosis / Q000276:immunology*; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology; D000939:Epitopes / Q000276:immunology*; D013045:Species Specificity
D000907:Antibodies, Bacterial; D000953:Antigens, Protozoan; D000939:Epitopes