Vaccinia virus growth factor stimulates tyrosine protein kinase activity of A431 cell epidermal growth factor receptors.
Infection of A431 cells with vaccinia virus, or exposure to a mitogenic polypeptide secreted by vaccinia virus-infected cells, induces tyrosine phosphorylation of epidermal growth factor receptors.
D002294:Carcinoma, Squamous Cell / Q000378:metabolism; D002460:Cell Line; D002472:Cell Transformation, Viral; D004789:Enzyme Activation; D066246:ErbB Receptors / Q000378:metabolism*; D006133:Growth Substances / Q000502:physiology*; D006801:Humans; D010766:Phosphorylation; D019000:Phosphotyrosine; D011505:Protein-Tyrosine Kinases / Q000378:metabolism*; D014443:Tyrosine / Q000031:analogs & derivatives / Q000032:analysis; D014616:Vaccinia virus / Q000235:genetics*; D014764:Viral Proteins / Q000502:physiology*
D006133:Growth Substances; D014764:Viral Proteins; D019000:Phosphotyrosine; D014443:Tyrosine; D066246:ErbB Receptors; D011505:Protein-Tyrosine Kinases