Immunocytochemical study of a trabecular carcinoma of the skin (Merkel cell tumor). Case report.
The existence of different neuroendocrine markers was investigated by immunocytochemistry in a case of Merkel cells tumor. Neuroplastic cells contain NSE,NF,CK and chromogranin A i.r. On the basis of the results the neuroendocrine nature of this uncommon neoplasm of the skin is confirmed and it is suggested that chromogranin A could represent an additional marker for Merkel cells tumors.
D000230:Adenocarcinoma / Q000276:immunology / Q000378:metabolism* / Q000473:pathology; D000368:Aged; D053379:Chromogranin A; D002864:Chromogranins / Q000378:metabolism; D006801:Humans; D007124:Immunoenzyme Techniques; D007382:Intermediate Filaments / Q000378:metabolism; D007633:Keratins / Q000378:metabolism; D008207:Lymphatic Metastasis; D008297:Male; D010751:Phosphopyruvate Hydratase / Q000378:metabolism; D012878:Skin Neoplasms / Q000276:immunology / Q000378:metabolism* / Q000473:pathology; D013194:Staining and Labeling
D053379:Chromogranin A; D002864:Chromogranins; D007633:Keratins; D010751:Phosphopyruvate Hydratase