title: [Passive transport of Ca2+ in vesiculated preparations of myocardial sarcolemma].
abstract: The highly purified vesicles of myocardial sarcolemma oriented outward mainly by the cytoplasmic side are used to show that Ca2+-calmodulin-dependent phosphorylation inhibits passive Ca2+-transport, while R24571, a blocking agent of calmodulin-dependent processes, removes this inhibitory effect. Passive Ca2+ transport is also inhibited by nicardipin with Ki (5 X 10(-8) M) and Mg2+. Tetrodotoxin and tetraethylammonium exert no effect on Ca2+-transport.
mesh_terms: D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D002118:Calcium / Q000378:metabolism*; D066298:In Vitro Techniques; D007473:Ion Channels / Q000187:drug effects / Q000378:metabolism*; D008274:Magnesium / Q000494:pharmacology; D009206:Myocardium / Q000378:metabolism* / Q000648:ultrastructure; D009529:Nicardipine / Q000494:pharmacology; D010766:Phosphorylation; D011817:Rabbits; D012508:Sarcolemma / Q000378:metabolism* / Q000648:ultrastructure
chemical_list: D007473:Ion Channels; D009529:Nicardipine; D008274:Magnesium; D002118:Calcium
vernacular_title: Passivnyĭ transport Ca2+ v vezikulirovannykh preparatakh sarkolemmy miokarda.