Lindane-induced changes in glucose and glutathione levels in cats.
Cats were given lindane (1 and 2 mg/kg i.v.) and the levels of glucose in blood and glutathione in blood and liver were measured at 30 min, 1, 2, 4 and 8 h. The results showed a sharp decrease in blood glutathione at an early interval with subsequent recovery, whereas there was no change in liver up to 2 h followed by a significant decrease at later intervals with no sign of recovery. The pesticide also showed a hypoglycemic effect at all intervals.
D000818:Animals; D001786:Blood Glucose; D002415:Cats; D005260:Female; D005978:Glutathione / Q000097:blood*; D001556:Hexachlorocyclohexane / Q000633:toxicity*; D007003:Hypoglycemia / Q000139:chemically induced; D007275:Injections, Intravenous; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008297:Male
D001786:Blood Glucose; D001556:Hexachlorocyclohexane; D005978:Glutathione