title: [Therapy with high-dose intravenous gamma globulin in the newborn infant with thrombocytopenia from passive immunization].
abstract: High doses of gammaglobulin intravenously have been found useful in controlling thrombocytopenia of a neonate born to a mother who developed acute idiopathic thrombocytopenic purpura during pregnancy. Administration of 0.4 gm/kg/day of intact gammaglobulin intravenously for five days was followed by dramatic rise of platelet count without any side-effect. After 1 month the platelet count was still normal. Passively-acquired immune thrombocytopenia of the newborn consequently is another indication for intravenous gammaglobulin therapy.
mesh_terms: D006801:Humans; D007112:Immunity, Maternally-Acquired; D007231:Infant, Newborn; D007275:Injections, Intravenous; D013921:Thrombocytopenia / Q000209:etiology / Q000276:immunology / Q000628:therapy*; D005719:gamma-Globulins / Q000008:administration & dosage*
chemical_list: D005719:gamma-Globulins
vernacular_title: La terapia con alte dosi di gammaglobuline endovena nel neonato affetto da trombocitopenia da immunizzazione passiva.