title: Early dentinogenesis in mice: von Korff fibres and their possible significance. A preliminary study by light and electron microscopy.
abstract: By light and electron microscopy we have confirmed the collagenous nature of von Korff fibres in early dentinogenesis in mice. Each fibre array begins as an argyrophil 'stem' lying between the outermost cells of the dental papilla, with finer divisions passing into the papilla. With the appearance of odontoblasts, a cone-like 'spray' of nonargyrophil fibres in continuity with the stem spreads peripherally between these cells to the dental epithelial basement membrane. After the sprays become immured in dentine matrix, the stems are removed. Later, new stems appear. Sprays are restricted to enamel-bearing parts of teeth. The possible nature and functions of von Korff fibres are discussed.
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development; D003810:Dentinogenesis; D007180:Incisor / Q000254:growth & development / Q000648:ultrastructure; D051379:Mice; D008854:Microscopy, Electron; D008963:Molar / Q000254:growth & development / Q000648:ultrastructure; D013194:Staining and Labeling; D013997:Time Factors