[A case of multiple myeloma responding very well to the combination of K18 with prednisolone].
A case of multiple myeloma refractory to various anticancer drugs was effectively treated with the combination of K 18 with prednisolone, which led to a remarkable decrease of serum M-protein and overall recovery. In 8 months of the treatment, although slight bone marrow suppression was noted, no severe side effect was observed. The patient has survived for more than one year in remission. We suggest that the combination of K18 with prednisolone may be effective for multiple myeloma which is unresponsive to treatment with anticancer drugs.
D004338:Drug Combinations / Q000008:administration & dosage / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D000922:Immunotoxins; D008558:Melphalan / Q000008:administration & dosage* / Q000627:therapeutic use; D008875:Middle Aged; D009101:Multiple Myeloma / Q000628:therapy*; D011239:Prednisolone / Q000008:administration & dosage* / Q000627:therapeutic use; D012074:Remission Induction; D005719:gamma-Globulins / Q000008:administration & dosage* / Q000627:therapeutic use
D004338:Drug Combinations; D000922:Immunotoxins; C045927:K-18 conjugate; D005719:gamma-Globulins; D011239:Prednisolone; D008558:Melphalan