Restoration of skin defects with fibrin glue.
After experiments with absorbable bioplasts for substitution of skin defects, this time the absorbable fibrin glue named Tissucol was used by the authors. The experiments on 22 dogs unanimously proved that, beneath the layer of tissue adhesive, scarring occurred free of inflammation as compared to the controls where inflammatory phenomena were not excluded. The procedure has been found good and useful in high-degree burns and injuries up to their final management.
D000818:Animals; D007611:Aprotinin; D004285:Dogs; D004338:Drug Combinations; D005176:Factor XIII; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen; D012867:Skin / Q000293:injuries*; D012879:Skin Physiological Phenomena; D013917:Thrombin; D014014:Tissue Adhesives; D014945:Wound Healing
D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives; D005340:Fibrinogen; D005176:Factor XIII; D007611:Aprotinin; D013917:Thrombin