[Activity of the nucleolar organizers of the cells in epithelial tumors of the human large intestine].
Normal, adenoma and cancer cell nucleoli have been studied by silver impregnation in 13 cancer patients, 48 patients with adenoma (14-tubular, 35-tubulovillous and villous) and 15 controls. It has been shown that the content of silver granules per cell was significantly higher (34.0 +/- 9.7) in cancer cells than in the control (12.3 +/- 3.1). Adenoma cells were heterogeneous. Most villous adenomas, like adenocarcinomas, had high content of Ag granules per cell. The importance of these findings for theoretical and clinical oncology is discussed.
D000230:Adenocarcinoma / Q000648:ultrastructure; D000236:Adenoma / Q000648:ultrastructure; D002277:Carcinoma / Q000648:ultrastructure*; D006801:Humans; D007413:Intestinal Mucosa / Q000648:ultrastructure; D007414:Intestinal Neoplasms / Q000648:ultrastructure*; D007420:Intestine, Large / Q000648:ultrastructure*; D009697:Nucleolus Organizer Region / Q000648:ultrastructure*; D013194:Staining and Labeling / Q000379:methods
Aktivnost' iadryshkovykh organizatorov kletok épitelial'nykh opukholeĭ tolstoĭ kishki cheloveka.