title: Two kinds of transducer.
abstract: After recognizing that there are two kinds of biotransducers, attention is focused on the kind that transduces energy, as in muscle or in ion pumps. Using muscle as the example, it is suggested that the essential elements in the transducer (S-1 segment of myosin) are (1) An ATPase site that, in time, is occupied by a succesion of ligands ("intermediates"); (2) A spatially separate site for binding a second ligand (actin, in the case of muscle) that can be held in a variety of spatial relations; and (3) A transmitting mechanism (electric field, propagated structural distortion) that allows the conformation impressed by the ligand of (1) to be conducted over space and impose a specific relation to the ligand of (2).
mesh_terms: D055592:Biophysical Phenomena; D001703:Biophysics; D004734:Energy Metabolism; D009119:Muscle Contraction; D009132:Muscles / Q000502:physiology*