Intravascular hemolytic transfusion reaction without detectable antibodies: A case report and review of literature.
A case of intravascular hemolytic transfusion reaction without detectable antibodies occurring in a 55-year-old male is reported. Specificity for the C antigen in the Rh system was demonstrated by technetium-99m red cell survival studies. A cell-mediated mechanism of hemolysis was suspected and investigated. Previously reported cases are reviewed and discussed. The entity of intravascular hemolytic transfusion reaction associated with minimal symptoms and no detectable antibodies deserves further investigation.
D000954:Antigens, Surface; D000939:Epitopes; D004903:Erythrocyte Aggregation / Q000209:etiology*; D004905:Erythrocyte Aging; D017707:Erythrocyte Transfusion; D004912:Erythrocytes / Q000276:immunology; D006456:Hemoglobinuria / Q000097:blood; D006801:Humans; D007111:Immunity, Cellular; D007518:Isoantibodies / Q000032:analysis; D008213:Lymphocyte Activation; D008297:Male; D008875:Middle Aged; D012204:Rh-Hr Blood-Group System / Q000276:immunology; D013667:Technetium; D065227:Transfusion Reaction
D000954:Antigens, Surface; D000939:Epitopes; D007518:Isoantibodies; D012204:Rh-Hr Blood-Group System; D013667:Technetium