Mössbauer spectroscopy of haemoglobins. Study of the relationship of Fe2+ electronic and molecular structure of the active site.
Human normal, adult and foetal oxyhaemoglobins and oxyhaemoglobins from leukaemic patients were studied, by Mössbauer spectroscopy. The estimations of quadrupole splitting delta EQ and isomer shift delta allow one to distinguish between adult, foetal and leukaemic oxyhaemoglobins. The differences in the Fe2+ electronic structure and active site molecular structure of foetal and leukaemic oxyhaemoglobins were analyzed.
D000494:Allosteric Regulation; D001665:Binding Sites; D005296:Ferrous Compounds; D005319:Fetal Hemoglobin; D006418:Heme; D006454:Hemoglobins; D006801:Humans; D007938:Leukemia / Q000097:blood; D010108:Oxyhemoglobins; D013057:Spectrum Analysis
D005296:Ferrous Compounds; D006454:Hemoglobins; D010108:Oxyhemoglobins; D006418:Heme; D005319:Fetal Hemoglobin