[Elimination of T lymphocytes from the bone marrow in HLA-incompatible bone marrow transplantation].
The method presented is very well suited to eliminate T-lymphocytes from great amounts of bone-marrow. The stem cells required to reconstitute the bone-marrow are enriched in this way. It can be completely performed in a closed system. Any contamination with germs is excluded. It can be reproduced well and learnt quickly. It takes 10 hours for two trained co-workers to process 1,500 ml of bone-marrow. The vitality of cells is very good (100%). Its suitability for transplantation has still to be checked.
D001854:Bone Marrow Cells; D016026:Bone Marrow Transplantation; D002469:Cell Separation; D006650:Histocompatibility Testing; D006801:Humans; D013601:T-Lymphocytes
T-Lymphozytenelimination aus dem Knochenmark bei der HLA-inkompatiblen Knochenmarktransplantation.