Primary choriocarcinoma of mediastinum with immunohistochemical study and review of the literature.
Primary germinal tumors of the mediastinum are extremely rare. Most germ cell tumors in that location occur as metastasis from testis. A case report with immunocytochemical studies is described. Histologically, the tumor had features of choriocarcinoma and with immunoperoxidase technique stained positively for Beta human chorionic gonadotropin (BHCG). The patient is alive and asymptomatic 2 years post surgery and chemotherapy.
D000328:Adult; D002272:Carcinoembryonic Antigen / Q000032:analysis; D002822:Choriocarcinoma / Q000473:pathology* / Q000601:surgery; D006063:Chorionic Gonadotropin / Q000032:analysis; D005500:Follow-Up Studies; D006651:Histocytochemistry; D006801:Humans; D007124:Immunoenzyme Techniques; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D008297:Male; D008479:Mediastinal Neoplasms / Q000473:pathology* / Q000601:surgery; D000509:alpha-Fetoproteins / Q000032:analysis
D002272:Carcinoembryonic Antigen; D006063:Chorionic Gonadotropin; D000509:alpha-Fetoproteins; D007770:L-Lactate Dehydrogenase