[Shigella toxicity in immunological tolerance].
The toxic effect of killed and live Shigella sonnei cultures on normal mice and on mice, tolerant to Shigella O-antigen and to human erythrocytes of different blood groups (in the ABO system) was under study. The toxicity of shigellae, introduced intraperitoneally, has been found to depend on their viability, on their capacity for penetration into the blood, and on the split character of immunological tolerance to Shigella antigens.
D000017:ABO Blood-Group System / Q000276:immunology; D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D000942:Antigens, Bacterial / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology; D004926:Escherichia coli / Q000276:immunology / Q000472:pathogenicity; D006801:Humans; D007108:Immune Tolerance; D007114:Immunization; D007928:Lethal Dose 50; D051379:Mice; D019081:O Antigens; D012764:Shigella sonnei / Q000276:immunology / Q000472:pathogenicity*; D013997:Time Factors; D014774:Virulence
D000017:ABO Blood-Group System; D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D019081:O Antigens
Toksichnost' shigell pri immunologicheskoĭ tolerantnosti.