[Effects of different saccharose and electrolyte concentrations on preserved erythrocytes].
Preservation solutions for buffy coat-free red cell concentrates with sucrose concentrations from 234 decreasing up to 15 mmol per 1 solution were tested. The hemolysis rate increased from 0.5 up to 1.9% by decreasing the sucrose concentration. The red cell volume was unchanged at low sucrose concentrations. No differences were noticed in ATP content and morphological changes. A considerable extracellular pH shift at high sucrose concentration exists only at the beginning of storage. A sucrose concentration of 30-50 mmol/l solution (3-5 mmol per unit red cell concentrate) at an ionic strength of 0.16 proves to be most suitable.
D000255:Adenosine Triphosphate / Q000097:blood; D001793:Blood Preservation / Q000379:methods*; D004573:Electrolytes; D004911:Erythrocyte Volume; D004912:Erythrocytes / Q000032:analysis; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006461:Hemolysis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D012996:Solutions; D013395:Sucrose / Q000494:pharmacology*
D004573:Electrolytes; D006454:Hemoglobins; D012996:Solutions; D013395:Sucrose; D000255:Adenosine Triphosphate
Zum Einfluss unterschiedlicher Saccharose- und Elektrolytkonzentrationen auf konservierte Erythrozyten.