Immunochemical comparisons of proteins that bind heme and bilirubin: human serum albumin, alpha-fetoprotein and glutathione S-transferases from liver, placenta and erythrocyte.
1. Antisera to native or unfolded glutathione S-transferase from human liver recognize either antigen but do not recognize native or unfolded glutathione S-transferase from human placenta. 2. Antisera to native or unfolded glutathione S-transferase from placenta recognize either antigen but do not recognize native or unfolded glutathione S-transferase from liver. 3. Antisera to unfolded human serum albumin crossreacts with unfolded alpha-fetoprotein but does not recognize unfolded glutathione S-transferase.
D001663:Bilirubin / Q000378:metabolism; D003429:Cross Reactions; D004797:Enzyme-Linked Immunosorbent Assay; D004912:Erythrocytes / Q000201:enzymology*; D005982:Glutathione Transferase / Q000276:immunology* / Q000378:metabolism; D006418:Heme / Q000378:metabolism; D006801:Humans; D008099:Liver / Q000201:enzymology*; D010920:Placenta / Q000201:enzymology*; D011485:Protein Binding; D012709:Serum Albumin / Q000276:immunology / Q000378:metabolism; D000509:alpha-Fetoproteins / Q000276:immunology / Q000378:metabolism
D012709:Serum Albumin; D000509:alpha-Fetoproteins; D006418:Heme; D005982:Glutathione Transferase; D001663:Bilirubin