[Interferon-inducing and antiviral activity of maleic anhydride copolymers].
Data on synthesis of new polymer compounds with potential interferon-inducing and antiviral activity are presented. Maleic anhydride (MA)-based alternating copolymers, in particular, copolymers of divinyl ether with MA containing five-member oxygen cycles in the chain, as well as furan copolymers with MA, were shown to be promising interferon inducers. The antiviral activity was found in copolymers based on allene hydrocarbons.
D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D004675:Encephalitis, Tick-Borne / Q000188:drug therapy; D005663:Furans / Q000494:pharmacology*; D007369:Interferon Inducers / Q000494:pharmacology* / Q000627:therapeutic use; D007372:Interferons / Q000097:blood; D007739:L Cells / Q000187:drug effects; D008299:Maleic Anhydrides / Q000494:pharmacology* / Q000627:therapeutic use; D051379:Mice; D011108:Polymers / Q000494:pharmacology* / Q000627:therapeutic use; D013329:Structure-Activity Relationship; D013997:Time Factors; D014753:Vinyl Compounds / Q000494:pharmacology
D000998:Antiviral Agents; D005663:Furans; D007369:Interferon Inducers; D008299:Maleic Anhydrides; D011108:Polymers; D014753:Vinyl Compounds; C100195:vinyl ether; D007372:Interferons
Interferonindutsiruiushchaia i protivovirusnaia aktivnost' sopolimerov maleinovogo angidrida.