title: Treatment of acanthosis nigricans with etretinate (Tigason) in a patient with Lawrence-Seip syndrome (generalized lipodystrophy).
abstract: The major symptoms of Lawrence-Seip syndrome or generalized lipodystrophy consist of muscle hypertrophy, loss of subcutaneous fat, hyperlipaemia, diabetes mellitus and acanthosis nigricans. We have successfully treated acanthosis nigricans in a patient with Lawrence-Seip syndrome.
mesh_terms: D000052:Acanthosis Nigricans / Q000188:drug therapy* / Q000209:etiology; D000328:Adult; D005050:Etretinate / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008060:Lipodystrophy / Q000150:complications*
chemical_list: D005050:Etretinate