[Dynamics of change in the antibacterial activity of mouse peritoneal cells during the development of experimental influenzal infection].
The method of the radiometric determination of the antibacterial activity of peritoneal cells in the process of the development of viral infection has been approved. The genetically determined specific level of the antibacterial activity of these cells in different strains of mice has been established. The development of the lethal form of experimental influenza A in mice has been shown to be accompanied by the mobilization of nonspecific protective factors, including the system of interferons and the antibacterial activity of peritoneal cells. The latter factor is, seemingly, insufficient for ensuring the necessary level of protection in the animals, whose death occurs at a shorter time than that necessary for the development of specific immune response.
D000818:Animals; D007113:Immunity, Innate; D007372:Interferons / Q000097:blood; D008264:Macrophages / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009976:Orthomyxoviridae Infections / Q000276:immunology*; D010529:Peritoneal Cavity / Q000166:cytology / Q000276:immunology*; D012486:Salmonella typhimurium / Q000276:immunology; D013997:Time Factors
D007372:Interferons
Dinamika izmeneniia antibakterial'noĭ aktivnocti peritoneal'nykh kletok mysheĭ pri razvitii éksperimental'noĭ grippoznoĭ infektsii.