The efficacy of combined therapy with methotrexate and 5-fluorouracil from the view point of cellular PRPP level of L1210 cells and HeLa S3 cells.
D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000494:pharmacology*; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage; D006367:HeLa Cells; D006801:Humans; D007939:Leukemia L1210 / Q000378:metabolism*; D008727:Methotrexate / Q000008:administration & dosage; D051379:Mice; D010428:Pentosephosphates / Q000378:metabolism*; D010754:Phosphoribosyl Pyrophosphate / Q000378:metabolism*
D010428:Pentosephosphates; D010754:Phosphoribosyl Pyrophosphate; D005472:Fluorouracil; D008727:Methotrexate