Cis-platinum therapy in a patient with extragonadal seminoma and hydronephrosis of the only functioning kidney. A case report.
A 41-year-old man presented with a massive abdominal extragonadal seminoma. His only functioning kidney was hydronephrotic and the serum creatinine clearance was 55 ml/min. He was given combination chemotherapy including cis-platinum. At 46 months' follow-up he has improved renal function and no evidence of active disease.
D000008:Abdominal Neoplasms / Q000150:complications / Q000188:drug therapy*; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use*; D004407:Dysgerminoma / Q000150:complications / Q000188:drug therapy* / Q000556:secondary; D006801:Humans; D006869:Hydronephrosis / Q000150:complications*; D008297:Male; D014747:Vinblastine / Q000008:administration & dosage
D001761:Bleomycin; D014747:Vinblastine; D002945:Cisplatin