Reconstructive microsurgery of the rabbit oviduct using serosal microsutures and fibrin sealant.
Microsurgical reconstruction of the rabbit oviduct was undertaken utilizing either: A: fibrin sealant in a thick layer applied to two or three serosa microsutures (20 rabbits), B: fibrin sealant only (20 rabbits), and C: microsutures only (20 rabbits). The pregnancy rates and the patency rates of the oviducts showed no significant differences between the three groups. However, the formation of adhesions at the site of reanastomosis was significantly lower and the total duration of surgery significantly shortened when fibrin sealant was employed. It is concluded that fibrin sealant combined with serosa microsutures certainly is the most convenient method in human tubal microsurgery seeing that this method maintains a higher tensil strength at the site of reanastomosis as compared to group B and avoid the risk of mucosal lesions as compared to group C.
D000818:Animals; D007611:Aprotinin; D004338:Drug Combinations; D005176:Factor XIII; D005187:Fallopian Tubes / Q000473:pathology / Q000601:surgery*; D005260:Female; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen; D008866:Microsurgery / Q000379:methods*; D011247:Pregnancy; D011817:Rabbits; D013536:Suture Techniques; D013917:Thrombin; D000267:Tissue Adhesions / Q000209:etiology
D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen; D005176:Factor XIII; D007611:Aprotinin; D013917:Thrombin