title: [Quality of life and time of survival following diagnosis of a bronchus carcinoma in 267 patients from 1977 to 1984].
abstract: The data of all patients diagnosed and/or treated for lung cancer at the Zürcher Höhenklinik Wald in the years 1977 to 1984 were analyzed retrospectively. In 1986 follow-up interviews were conducted with surviving patients and physicians of all patients. Quality of life was assessed by a performance scale in three stages, adapted from Karnofsky. Overall survival in the 267 patients (age 65 +/- 10 years, 85% males, 91% smokers) was 18 months. 14 patients have thus far lived longer than 5 years after diagnosis, resulting in a 5-year survival (Kaplan-Meier) of 9.6%. Statistical analysis showed survival to be significantly influenced by the performance scale and stage of disease at the time of diagnosis. Decision trees or algorithms calculated with a new computer program (CART) established the importance of performance scale, stage of disease and patients' age, followed by histology and patient's sex for therapeutic decisions and prognosis in lung cancer. Surgical resection in stage I and II was feasible in 20% of all patients only, with a 5-year survival rate of 36%.
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010166:Palliative Care; D011379:Prognosis; D011788:Quality of Life; D013557:Switzerland
vernacular_title: Lebensqualität und -dauer nach Diagnose eines Bronchuskarzinoms bei 267 Patienten in den Jahren 1977 bis 1984.