Galanin- and neuropeptide Y-like immunoreactivities coexist in paravertebral sympathetic neurones of the cat.
Paraffin sections of feline cervicothoracic sympathetic ganglia were investigated for galanin-like immunoreactivity (galanin-LI) by means of immunohistochemistry. Galanin-LI was observed in postganglionic neurones, which, as revealed by investigation of adjacent sections, also displayed neuropeptide Y (NPY)-LI. Additional NPY-LI ganglion cells were devoid of galanin-LI. Galanin-LI did not coexist with vasoactive intestinal polypeptide-LI in neurones. Galanin-LI nerve fibres and paraganglionic cells were few in number. The findings suggest that galanin may participate in sympathetic control of organ function.
D000818:Animals; D001338:Autonomic Fibers, Postganglionic / Q000378:metabolism; D002415:Cats; D019004:Galanin; D005728:Ganglia, Sympathetic / Q000378:metabolism*; D006168:Guinea Pigs; D007124:Immunoenzyme Techniques; D009478:Neuropeptide Y / Q000378:metabolism*; D010455:Peptides / Q000378:metabolism*; D051381:Rats; D013045:Species Specificity; D014660:Vasoactive Intestinal Peptide / Q000378:metabolism
D009478:Neuropeptide Y; D010455:Peptides; D014660:Vasoactive Intestinal Peptide; D019004:Galanin