title: Changes in total and mitochondrial nucleic acid content in aging Caryedon serratus Oliver (Coleoptera).
abstract: Aging in the beetle Caryedon serratus was accompanied by a decline in total DNA content (9.28% in males and 9.79% in females). Mitochondrial DNA remained constant until the 11th day of age and then decreased gradually with advancing age in both sexes. RNA content and the RNA/DNA ratio showed similar changes in whole body as well as mitochondrial fractions. The two parameters decreased continuously and significantly (p less than 0.001) in males whereas in females an initial rise during the reproductive period was followed by decline until death. The observations suggest that there is a loss of mitochondria in the senescent period and a decline in the total nucleic acid content and protein synthetic capacity of C. serratus.
mesh_terms: D000375:Aging / Q000378:metabolism*; D000818:Animals; D001517:Coleoptera / Q000032:analysis*; D004247:DNA / Q000032:analysis*; D004272:DNA, Mitochondrial / Q000032:analysis*; D005260:Female; D008297:Male; D008928:Mitochondria / Q000032:analysis; D012313:RNA / Q000032:analysis*; D012737:Sex Factors
chemical_list: D004272:DNA, Mitochondrial; D012313:RNA; D004247:DNA