Natural cytotoxicity in draining lymph nodes of squamous cell cancer in the maxillofacial region.
There is at present very little information available, including the presented preliminary data, concerning NK activity in patients with head and neck cancer. The objective of the present investigation was to study NK activity in peripheral blood (PB) and regional lymph nodes (LNs) in patients with different stages of head and neck cancer. Furthermore, phenotypic characterization of lymph node cells was performed. Finally, the in vitro response of mononuclear cells isolated from blood and lymph nodes to interferon was investigated.
D002294:Carcinoma, Squamous Cell / Q000097:blood / Q000473:pathology*; D003601:Cytotoxicity Tests, Immunologic; D003602:Cytotoxicity, Immunologic; D006801:Humans; D007372:Interferons / Q000494:pharmacology; D007694:Killer Cells, Natural / Q000187:drug effects / Q000276:immunology*; D008198:Lymph Nodes / Q000473:pathology*; D008214:Lymphocytes / Q000145:classification / Q000187:drug effects; D009062:Mouth Neoplasms / Q000097:blood / Q000473:pathology*; D009333:Neck; D010641:Phenotype
D007372:Interferons