title: Interferons and systemic lupus erythematosus.
abstract: An array of data exists in patients with systemic lupus erythematosus which strong supports a role for interferon (IFN) in the disease process. The mechanism(s) which lead to an elevation of serum IFN in patients with SLE is unclear. IFN abnormalities may also contribute to a defect in natural killer function.
mesh_terms: D000917:Antibody Formation; D006801:Humans; D007108:Immune Tolerance; D007111:Immunity, Cellular; D007372:Interferons / Q000502:physiology*; D007694:Killer Cells, Natural / Q000276:immunology; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D008264:Macrophages / Q000276:immunology
chemical_list: D007372:Interferons