Possible implication of an efferent neuropathy in vestibular upset.
This essay examines two possible mechanisms whereby a neuropathy affecting the efferent vestibular innervation may cause incoordination of vestibular afferent input to the Vestibular Integrating Centres: firstly, by loss of the normal fine control of afferent impulses; secondly, by a disruption of the sodium-potassium pump mechanism that maintains the ionic stability of the inner ear fluids.
D006801:Humans; D007473:Ion Channels / Q000378:metabolism; D007761:Labyrinthine Fluids / Q000378:metabolism; D009422:Nervous System Diseases / Q000503:physiopathology*; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D014717:Vertigo / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology*; D014725:Vestibular Nerve / Q000503:physiopathology*; D014722:Vestibule, Labyrinth / Q000503:physiopathology*
D007473:Ion Channels; D012964:Sodium; D011188:Potassium