title: Effects of pressure and potassium chloride on the aggregation of poly(gamma-benzyl-L-glutamate) in liposomal bilayers.
abstract: Fluorescence depolarization studies were made on dimyristoylphosphatidylcholine liposomes containing four kinds of dansylated poly(gamma-benzyl-L-glutamate) with different degrees of polymerization or hydrocarbon chain lengths under high pressure at up to 981 bar (1 bar = 10 MPa). Potassium chloride promoted the aggregation of the synthetic peptides in liposomal bilayers at both atmospheric and high pressure. The chain lengths of the hydrocarbons of the peptides had more influence than their degrees of polymerization on aggregation.
mesh_terms: D004134:Dimyristoylphosphatidylcholine; D008051:Lipid Bilayers; D046911:Macromolecular Substances; D010455:Peptides; D011099:Polyglutamic Acid / Q000031:analogs & derivatives; D011189:Potassium Chloride; D011312:Pressure; D013050:Spectrometry, Fluorescence
chemical_list: D008051:Lipid Bilayers; D046911:Macromolecular Substances; D010455:Peptides; C003172:poly-gamma-benzyl-L-glutamate; D011099:Polyglutamic Acid; D011189:Potassium Chloride; D004134:Dimyristoylphosphatidylcholine