title: Age-related sensitivity of rats to induction of anaemia.
abstract: The intensity of symptoms of experimental anaemia significantly depended on the age of animals. It increased in elder rats after administration of substances with haemolytic potential (phenylhydrazine, phenacetin, 3-chloro-4-benzyloxyphenylacetic acid, nitrobenzene) whereas it decreased after cyclophosphamide-induced erythropoietic suppression.
mesh_terms: D000367:Age Factors; D000740:Anemia / Q000097:blood / Q000139:chemically induced*; D000818:Animals; D003520:Cyclophosphamide / Q000009:adverse effects; D064420:Drug-Related Side Effects and Adverse Reactions; D004906:Erythrocyte Count; D006454:Hemoglobins / Q000032:analysis; D008297:Male; D009578:Nitrobenzenes / Q000009:adverse effects; D010615:Phenacetin / Q000009:adverse effects; D010648:Phenylacetates / Q000009:adverse effects; D010659:Phenylhydrazines / Q000009:adverse effects; D051381:Rats; D011919:Rats, Inbred Strains; D012156:Reticulocytes; D012307:Risk Factors
chemical_list: D006454:Hemoglobins; D009578:Nitrobenzenes; D010648:Phenylacetates; D010659:Phenylhydrazines; C030299:phenylhydrazine; C023677:3-chloro-4-benzoyloxyphenylacetic acid; D003520:Cyclophosphamide; C036077:nitrobenzene; D010615:Phenacetin