title: Malignant melanoma of the cervix. Report of a case.
abstract: A malignant melanoma of the cervix, a rare neoplasm, was found to have an unusual cytologic pattern, similar to that of a leiomyosarcoma. A biopsy sample was diagnosed as cervical malignant melanoma of the spindle cell type. Some neoplastic cells in the tissue contained melanin pigment, whereas none of the abnormal cells in the cervical scrapes, except for an abnormal giant cell, had visible cytoplasmic pigment. The abnormal cells in the cervical scrape specimen were spindle-shaped, as were their nuclei, which is why the cytologic pattern was interpreted as that of a leiomyosarcoma. Evidence from this and previously reported cases shows that malignant melanoma must be considered as a possible source of exfoliated abnormal nonpigmented spindle-shaped cells in a cervicovaginal cell sample.
mesh_terms: D002467:Cell Nucleus / Q000473:pathology; D003593:Cytoplasm / Q000473:pathology; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology; D008543:Melanins / Q000032:analysis; D008545:Melanoma / Q000473:pathology*; D008875:Middle Aged; D013194:Staining and Labeling; D002583:Uterine Cervical Neoplasms / Q000473:pathology*; D014625:Vaginal Neoplasms / Q000473:pathology
chemical_list: D008543:Melanins