[Selectivity of inhibition of enzyme secretion by the pancreas after introduction of amylase into the duodenum].
Intraduodenal administration of both pancreatic and vegetative amylase induces inhibition of pancreatic secretion of the amylase. The secretion activated with intraduodenal administration of oxidized hydrolysine or i.v. administration of secretin, is also inhibited. High doses of intraduodenal amylase inhibit secretion of the juice's other components too. I.v. amylase inhibit secretion of bicarbonates and hydrolases in the pancreas. The selective inhibiting effect of amylase is sharply reduced with starch solution. The duodenum seems to be able to inhibit selectively the pancreatic enzymes secretion, this mechanism participating in urgent adaptations of the pancreatic juice enzyme range to properties of duodenal chyme.
D000681:Amylases / Q000378:metabolism / Q000494:pharmacology*; D000818:Animals; D001639:Bicarbonates / Q000378:metabolism; D004285:Dogs; D004386:Duodenum / Q000187:drug effects*; D008049:Lipase / Q000378:metabolism; D010179:Pancreas / Q000378:metabolism*; D010189:Pancreatic Juice / Q000378:metabolism*; D010447:Peptide Hydrolases / Q000378:metabolism; D011506:Proteins / Q000378:metabolism
D001639:Bicarbonates; D011506:Proteins; D008049:Lipase; D000681:Amylases; D010447:Peptide Hydrolases
Izbiratel'nost' tormozheniia sekretsii fermentov podzheludochnoĭ zhelezoĭ pri vvedenii amilazy v dvenadtsatiperstnuiu kishku.