[Features of the electrical responses of isolated neurons of the chick embryo spinal cord to L-glutamate application].
Isolated cells from the spinal cord of chick embryo were investigated under conditions of intracellular perfusion and voltage clamp using the method of rapid application of extracellular solutions. Two components were found in the L-glutamate-activated current: a fast-inactivating component and a steady one. The dose-response relationship demonstrated one-to-one interaction between L-glutamate and membrane receptor with Kd values about 0.75 X 10(-5) mol/l for the steady component and 3.2 X 10(-5) mol/l for the fast one.
D000818:Animals; D002642:Chick Embryo; D005971:Glutamates / Q000494:pharmacology*; D018698:Glutamic Acid; D007473:Ion Channels / Q000187:drug effects; D009431:Neural Conduction / Q000187:drug effects; D013116:Spinal Cord / Q000187:drug effects*; D013268:Stimulation, Chemical
D005971:Glutamates; D007473:Ion Channels; D018698:Glutamic Acid
Osobennosti élektricheskikh otvetov izolirovannykh neĭronov spinnogo mozga kurinogo émbriona na applikatsiiu L-glutamata.