title: Enhancement of Candida albicans killing activity of separated human epidermal cells by ultraviolet radiation.
abstract: Ultraviolet irradiation enhanced the Candida albicans killing activity of freshly separated human epidermal cells in vitro. The stimulation was dose-dependent and was not due to soluble extracellular factors acting on non-irradiated epidermal cells. The enhancement of the killing activity remained unchanged when epidermal cells were depleted of Langerhans cells. Protein synthesis inhibitors and prostaglandin antagonists abrogated the ultraviolet-induced augmentation of killing activity.
mesh_terms: D002176:Candida albicans; D002478:Cells, Cultured; D004307:Dose-Response Relationship, Radiation; D000078404:Epidermal Cells; D004817:Epidermis / Q000502:physiology; D006801:Humans; D007633:Keratins; D010587:Phagocytosis / Q000528:radiation effects*; D014466:Ultraviolet Rays
chemical_list: D007633:Keratins