[Kinetics of the ATP-activated ionic currents in the sensory neurons of the rat].
It is shown that ATP being applied to sensory neurons of the rat activates ionic currents with variable kinetics of desensitization. The rate constant of the most "rapid" component of these currents is about 30 ms. The rate constant of the most "slow" component is about 30 s. Pharmacology and ionic properties of different components of the ATP-activated current is, probably, identical.
D000255:Adenosine Triphosphate / Q000494:pharmacology*; D000818:Animals; D002478:Cells, Cultured; D005726:Ganglia, Parasympathetic / Q000187:drug effects; D005727:Ganglia, Spinal / Q000187:drug effects; D007473:Ion Channels / Q000187:drug effects*; D007700:Kinetics; D009475:Neurons, Afferent / Q000187:drug effects*; D009620:Nodose Ganglion / Q000187:drug effects; D051381:Rats; D013268:Stimulation, Chemical
D007473:Ion Channels; D000255:Adenosine Triphosphate
Kinetika ATF-aktiviruemykh ionnykh tokov v sensornykh neĭronakh krysy.