Immunohistological study in chordomas.
An immunohistological study of 15 chordomas, six chondrosarcomas, four liposarcomas and seven carcinomas on paraffin embedded samples using anti-cytokeratin, anti-epithelial membrane antigen (EMA), anti-S100 protein, anti-vimentin and anti-neurofilaments showed that chordomas has a characteristic immuno-staining, i.e. positive for cytokeratin, EMA, S100 protein and vimentin; and negative for neurofilaments. This immuno-staining allows a clear distinction of chordomas from other tumours.
D000230:Adenocarcinoma / Q000032:analysis; D002288:Adenocarcinoma, Mucinous / Q000032:analysis; D002813:Chondrosarcoma / Q000032:analysis; D002817:Chordoma / Q000032:analysis*; D006801:Humans; D007124:Immunoenzyme Techniques; D007633:Keratins / Q000032:analysis; D008080:Liposarcoma / Q000032:analysis; D008565:Membrane Proteins / Q000032:analysis; D018396:Mucin-1; D009418:S100 Proteins / Q000032:analysis; D014746:Vimentin / Q000032:analysis
D008565:Membrane Proteins; D018396:Mucin-1; D009418:S100 Proteins; D014746:Vimentin; D007633:Keratins