title: [Development of Escherichia diagnostic O-test systems].
abstract: The principles of the rational development of new diagnostic preparations, Escherichia agglutinating O-test systems consisting of polyvalent reagents (reapols), were worked out, and two O-test systems, "small" and "large", were made up on the basis of these reagents (for the identification of 22 and 151 Escherichia serovars, respectively). The agglutinogenicity of Escherichia O-antigens was studied and found to be poorly pronounced in 40% of cases. The practical scheme for the identification of Escherichia O-antigens (key to the O-test system) has been made; the scheme permitted the determination of 84.8% of Escherichia O-test strains, only 29.1% of the strains showing due positive reactions. Ways for improving these preparations are presented.
mesh_terms: D000372:Agglutination Tests / Q000379:methods; D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis* / Q000276:immunology; D001428:Bacterial Vaccines / Q000276:immunology; D000939:Epitopes / Q000032:analysis; D004925:Escherichia / Q000145:classification* / Q000276:immunology; D007114:Immunization / Q000379:methods; D007202:Indicators and Reagents; D019081:O Antigens; D011817:Rabbits; D012703:Serotyping / Q000379:methods
chemical_list: D000942:Antigens, Bacterial; D001428:Bacterial Vaccines; D000939:Epitopes; D007202:Indicators and Reagents; D019081:O Antigens
vernacular_title: Razrabotka diagnosticheskikh ésherikhioznykh O-test-sistem.