title: The differential descending projections from the anterior, central and posterior regions of the lateral hypothalamic area: an autoradiographic study.
abstract: The descending projection sites of the anterior, central (or tuberal) and posterior regions of the lateral hypothalamic area were studied by anterograde axonal transport after local injection of tritiated amino acids. The results show that the neurons of the anterior regions project to the lateral mammillary nucleus, the ventral tegmental area, the midbrain central gray and the anterior parts of the dorsal raphe nucleus. The neurons of the central region project in the same structures and extend a projection into the dorsal tegmentum at the level of the pontine central gray, the midbrain and pontine reticular nuclei. In the ventral tegmentum region, the substantia nigra pars compacta, the interpeduncular nucleus and the anterior group of raphe nuclei were also found to be labelled. The neurons of the posterior region of the lateral hypothalamic area extend a projection to the level of the prepositus hypoglossi nucleus and to the nucleus of solitary tract. In the ventral tegmentum they project at the level of posterior group of the raphe nuclei and the inferior olivary complex.
mesh_terms: D000344:Afferent Pathways / Q000033:anatomy & histology*; D000818:Animals; D001345:Autoradiography; D001370:Axonal Transport; D001921:Brain / Q000033:anatomy & histology*; D007026:Hypothalamic Area, Lateral / Q000033:anatomy & histology*; D051381:Rats; D011919:Rats, Inbred Strains; D014316:Tritium
chemical_list: D014316:Tritium