title: On the theory of the measurement of the first-pass pulmonary extraction using the indicator dilution technique.
abstract: Theory and concept of extraction involving invasive as well as non-invasive procedures to assess the first-pass extraction of tracers based on the indicator dilution technique are discussed. The experimental result of a non-invasive method using a gamma scintillation camera-computer system of first-pass pulmonary extraction of N-Isopropyl-123I-p-Iodoamphetamine (123I-IMP) are also discussed.
mesh_terms: D000662:Amphetamines / Q000378:metabolism; D000818:Animals; D003911:Dextrans / Q000378:metabolism; D004285:Dogs; D007204:Indium / Q000378:metabolism; D007457:Iodine Radioisotopes / Q000378:metabolism; D020367:Iofetamine; D008168:Lung / Q000000981:diagnostic imaging*; D008657:Metabolic Clearance Rate; D009942:Organometallic Compounds / Q000378:metabolism; D015609:Organotechnetium Compounds; D004369:Pentetic Acid / Q000378:metabolism; D011865:Radioisotope Dilution Technique; D011868:Radioisotopes / Q000378:metabolism; D011877:Radionuclide Imaging
chemical_list: D000662:Amphetamines; D003911:Dextrans; D007457:Iodine Radioisotopes; D009942:Organometallic Compounds; D015609:Organotechnetium Compounds; D011868:Radioisotopes; C034146:technetium Tc 99m dextran; D007204:Indium; D004369:Pentetic Acid; D020367:Iofetamine