Combined action of nicotinamide and adenine in preservation of packed red cells.
An alkaline resuspension solution "Erythronaph" with adenine and nicotinamide has been developed. It allows to preserve red blood cells for 35 days. Removing leukocytes and platelets up to 90% by brief warning of 24-hour blood prior to centrifugation combined with return of 10% of plasma provide further prolongation of storage of red blood cells in "Erythronaph".
D000225:Adenine / Q000494:pharmacology*; D001793:Blood Preservation / Q000379:methods*; D001803:Blood Transfusion; D004905:Erythrocyte Aging / Q000187:drug effects*; D017707:Erythrocyte Transfusion; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D009536:Niacinamide / Q000494:pharmacology*; D013696:Temperature
D009536:Niacinamide; D000225:Adenine