title: Multiple sclerosis: correlation of magnetic resonance imaging with cerebrospinal fluid findings.
abstract: MRI examination of 41 patients with clinical definite multiple sclerosis showed white matter lesions of high proton T2 signal consistent with demyelination in 76% and CSF abnormalities present in 76%. Of patients with CSF abnormalities, 26% had normal MRI scans; conversely 26% of patients with MRI abnormalities had negative CSF studies. Thus a significant number of multiple sclerosis patients had negative results on either MRI or CSF examination, while only 5% had normal results on both tests.
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid; D007136:Immunoglobulins / Q000134:cerebrospinal fluid; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid / Q000473:pathology*; D004676:Myelin Basic Protein / Q000134:cerebrospinal fluid; D043025:Oligoclonal Bands
chemical_list: D007074:Immunoglobulin G; D007136:Immunoglobulins; D004676:Myelin Basic Protein; D043025:Oligoclonal Bands