Renovascular hypertension after combination chemotherapy for testicular cancer.
Chemotherapy with cis-platinum, vinblastine and bleomycin for germ cell tumors of the testis has been highly effective but it also has been associated with acute and chronic vascular damage. We report the development of hypertension in a 38-year-old man after chemotherapy that was shown to be owing to nonatherosclerotic partial occlusion of the major branches of the left renal artery. Vascular complications following combination chemotherapy for germ cell tumors are reviewed.
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D001761:Bleomycin / Q000009:adverse effects; D002945:Cisplatin / Q000009:adverse effects; D006801:Humans; D006978:Hypertension, Renovascular / Q000139:chemically induced*; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000188:drug therapy*; D011859:Radiography; D012078:Renal Artery Obstruction / Q000139:chemically induced / Q000000981:diagnostic imaging; D013736:Testicular Neoplasms / Q000188:drug therapy*; D014747:Vinblastine / Q000009:adverse effects
D001761:Bleomycin; D014747:Vinblastine; D002945:Cisplatin