[Treatment of Kawasaki's syndrome with high dose intravenous gammaglobulins].
The apparition of coronary aneurysms in Kawasaki syndrome is the reason for the serious nature of this disease. Many attempts have been made to prevent this complication. Two children, respectively 10 and 28 months old, were treated in our unit with salicylate and high dose intravenous gammaglobulin by analogy with the treatment of idiopathic thrombocytopenic purpura. The clinical, electrical, radiological, echographic cardiac surveillance did not show any sign of aneurysms more than 6 months after the onset of the disease. Following the Furusho's study, high dose intravenous gammaglobulin seems to reduce the frequency of coronary aneurysms in patients with Kawasaki syndrome.
D006801:Humans; D007116:Immunization, Passive; D007223:Infant; D007275:Injections, Intravenous; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000188:drug therapy*; D005719:gamma-Globulins / Q000008:administration & dosage* / Q000494:pharmacology
D005719:gamma-Globulins
Traitement du syndrome de Kawasaki par gammaglobulines intra-veineuses à forte dose.