title: Chronic osteomyelitis treated by cancellous homografts and fibrin adhesion.
abstract: Twenty-nine bone defects caused by chronic osteomyelitis have been treated by radical excision of necrotic bone followed by packing the cavities with cancellous homografts held in position by a fibrin sealant. At follow-up three years after operation all except one had healed, though one case had needed a repeat operation. Good incorporation and remodelling of the grafts was observed even when the osseous bed was severely sclerosed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D007611:Aprotinin / Q000627:therapeutic use*; D001843:Bone Cements / Q000627:therapeutic use*; D016025:Bone Transplantation; D002648:Child; D002908:Chronic Disease; D004338:Drug Combinations / Q000627:therapeutic use; D005176:Factor XIII / Q000627:therapeutic use*; D005260:Female; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000601:surgery*; D013917:Thrombin / Q000627:therapeutic use*
chemical_list: D001843:Bone Cements; D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen; D005176:Factor XIII; D007611:Aprotinin; D013917:Thrombin