Skeletal disease, arthro-osteitis, in adult patients with pustulosis palmoplantaris.
A follow-up study of 13 patients with pustulosis palmoplantaris (PPP) and skeletal disease is reported. A prolonged and fluctuating course occurred in all patients. Nine patients had anterior chest wall involvement with erosions or ankylosis of the sternoclavicular, first sternocostal and/or manubriosternal joint together with sclerosis and often hyperostosis of adjacent bones, ossification/calcification of the first costal cartilage, and in 7 patients of the costoclavicular ligament. Spinal involvement in the form of spondylodiscitis, sclerosis of vertebral bodies, syndesmophytes, paravertebral ossifications and/or spondyloarthritis occurred in 11 patients, three of whom also had involvement of the sacroiliac joints. One patient had sclerosis of a pubic and ischial bone. Peripheral arthritis or tenosynovitis occurred in 5 patients, two of whom had signs of enthesopathy, and one also erosions. The presence of a distinct PPP syndrome is suggested.
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001168:Arthritis / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D001706:Biopsy; D001847:Bone Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D005533:Foot Dermatoses / Q000150:complications*; D006229:Hand Dermatoses / Q000150:complications*; D006801:Humans; D008297:Male; D010000:Osteitis / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D010166:Palliative Care; D011859:Radiography; D012872:Skin Diseases, Vesiculobullous / Q000150:complications*; D013122:Spinal Diseases / Q000150:complications / Q000000981:diagnostic imaging; D013492:Suppuration; D014054:Tomography
D000894:Anti-Inflammatory Agents, Non-Steroidal