Long-term results following surgical removal of pulmonary metastases in children with malignomas.
Between 1972 and June 1983, 21 children (mean age 9 years, range 20 months to 16.5 years) were operated on for pulmonary metastatic disease. Primary malignant tumors were Wilms-tumor (7 patients), osteogenic sarcoma (7 patients), Ewing's sarcoma (4 patients), hepatoblastoma (2 patients), and rhabdomyosarcoma (1 patient). The surgical intervention was part of a therapeutic pediatric oncological concept with curative purpose including chemotherapy and/or radiation in different combinations. Ten out of these 21 children survived disease-free 3 years and more after pulmonary metastasectomy. An aggressive surgical approach towards pulmonary metastatic disease in children thus appears to be justified.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D008175:Lung Neoplasms / Q000556:secondary / Q000601:surgery*; D009364:Neoplasm Recurrence, Local; D012516:Osteosarcoma / Q000601:surgery; D011379:Prognosis; D012189:Retrospective Studies; D012512:Sarcoma, Ewing / Q000601:surgery; D009396:Wilms Tumor / Q000601:surgery