title: [Effect of super-high doses of gamma-radiation on the level and metabolism of serotonin in the rat brain].
abstract: As early as 60 mi after gamma-irradiation of Wistar rats with a dose of 150 Gy the content of serotonin and 5-hydroxyindoleacetic acid decreases in the midbrain, hippocampus, and cerebral hemisphere cortex. The decrease is most pronounced in the midbrain where serotoninergic neurons are located. The changes are accumulated during the first 24 h following irradiation.
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism / Q000528:radiation effects*; D006897:Hydroxyindoleacetic Acid / Q000378:metabolism; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000378:metabolism*
chemical_list: D012701:Serotonin; D006897:Hydroxyindoleacetic Acid
vernacular_title: Vliianie sverkhvysokikh doz gamma-radiatsii na soderzhanie i obmen serotonina v golovnom mozge krys.