title: Congenital leukonychia striata.
abstract: Leukonychia striata of a unique appearance and distribution is described in a 51-year-old woman. Histopathologic examination of a specimen from the nail plate revealed a transverse band of parakeratosis on the ventral surface. Disturbance in keratinization on the nail plate is presumed to be secondary to abnormalities in the nail matrix. We review briefly the classification and pathogenesis of leukonychia, an interesting aberration in nail plate keratinization.
mesh_terms: D005260:Female; D006801:Humans; D007633:Keratins / Q000096:biosynthesis; D008875:Middle Aged; D009260:Nail Diseases / Q000151:congenital*; D014034:Toes
chemical_list: D007633:Keratins