The interaction between fibrinogen and 3H-arginine labelled proteins derived from fibrosarcoma in the presence of thrombin.
With the use of 3H-arginine labelled cationic proteins derived from fibrosarcoma induced by methylcholanthrene it has been shown in studies in vitro that these proteins interact with fibrinogen under the influence of thrombin. The effect of this reaction depends on the concentration of cationic proteins. it was calculated that 1 mg of fibrinogen can be interacted with 2.5 micrograms of 3H-arginine labelled cationic proteins. The clinical role of cationic proteins appearing in circulation in malignancy have been discussed briefly.
D000818:Animals; D005337:Fibrin / Q000502:physiology; D005340:Fibrinogen / Q000502:physiology*; D005342:Fibrinolysis; D005354:Fibrosarcoma / Q000097:blood* / Q000139:chemically induced; D008748:Methylcholanthrene; D009361:Neoplasm Invasiveness; D009363:Neoplasm Proteins / Q000502:physiology*; D051381:Rats; D013917:Thrombin / Q000502:physiology*
D009363:Neoplasm Proteins; D008748:Methylcholanthrene; D005337:Fibrin; D005340:Fibrinogen; D013917:Thrombin