[Double action potentials in the command neurons of Helix pomatia in response to the action of cobalt ions].
Cobalt chloride (20 mmol/l) in physiological solution results in generation of doublets of spikes in Helix pomatia command neurons in response to intracellularly injected depolarizing current. The extraspikes arise in arborizations of neuron and are determined by influx sodium ions. It is supposed that facilitation of extraspikes in apparently due to long-lasting blockade of calcium-dependent potassium current by Co2+ ions.
D000200:Action Potentials / Q000187:drug effects*; D000818:Animals; D002118:Calcium / Q000502:physiology; D003035:Cobalt / Q000494:pharmacology*; D005724:Ganglia / Q000187:drug effects* / Q000502:physiology; D006372:Helix, Snails; D066298:In Vitro Techniques; D007473:Ion Channels / Q000187:drug effects* / Q000502:physiology; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism
D007473:Ion Channels; D003035:Cobalt; D012964:Sodium; D011188:Potassium; D002118:Calcium
Dvoĭnye potentsialy deĭstviia v komandnykh neĭronakh vinogradnoĭ ulitki v usloviiakh deĭstviia ionov kobal'ta.