Developmental expression of two forms of pp60c-src in mouse brain.
The expression during mouse development of two forms of protein-tyrosine kinase pp60c-src, pp60 and pp60+, was investigated. At embryonic day 9 (E9), only pp60 was detected in whole-brain lysates. A trace of pp60+ was first seen at E10. In E18 embryos and in adults, pp60+ was the predominant form of pp60c-src in forebrain and midbrain lysates.
D000818:Animals; D001921:Brain / Q000196:embryology* / Q000201:enzymology; D001931:Brain Mapping; D007158:Immunologic Techniques; D008099:Liver / Q000201:enzymology; D051379:Mice; D011505:Protein-Tyrosine Kinases / Q000235:genetics*; D011518:Proto-Oncogene Proteins / Q000378:metabolism*; D016392:Proto-Oncogene Proteins pp60(c-src); D013116:Spinal Cord / Q000196:embryology / Q000201:enzymology
D011518:Proto-Oncogene Proteins; D011505:Protein-Tyrosine Kinases; D016392:Proto-Oncogene Proteins pp60(c-src)