title: [Ampicillin pharmacokinetics in prostatic adenoma patients].
abstract: Studies on ampicillin pharmacokinetics in patients with prostate adenoma showed that adenoma did not influence the antibiotic kinetics. The ampicillin maximum concentration in tissues and organs of the urinary corresponded to the peak concentrations in blood. Therefore, development of dosage regimens providing the drug efficient concentrations in tissues and organs of the urinary tract should be based on ampicillin kinetics in the blood.
mesh_terms: D000328:Adult; D000368:Aged; D000667:Ampicillin / Q000032:analysis / Q000493:pharmacokinetics*; D001681:Biological Assay; D006801:Humans; D008297:Male; D008875:Middle Aged; D009176:Mycoplasma mycoides / Q000378:metabolism; D011470:Prostatic Hyperplasia / Q000378:metabolism*; D013997:Time Factors; D014018:Tissue Distribution; D014551:Urinary Tract / Q000378:metabolism
chemical_list: D000667:Ampicillin
vernacular_title: Farmakokinetika ampitsillina u bol'nykh s adenomoĭ predstatel'noĭ zhelezy.