title: [New strain-specific determinants in the hemagglutinins of influenza B viruses isolated in 1983-1984].
abstract: A comparative study of sensitivity to inhibitors and antigenic composition of hemagglutinins of influenza B virus strains isolated in the epidemic season of 1983-1984 and those circulating in 1940-1981 was carried out. The method of selective adsorption of highly active rabbit and rat sera demonstrated that hemagglutinins of contemporary influenza B viruses had both common cross-reacting determinants with previously circulating variants and qualitatively different, strain-specific ones. Among the variants isolated in 1983-1984, three subgroups of viruses were detected with different strain-specific hemagglutinin determinants.
mesh_terms: D000327:Adsorption; D000818:Animals; D003429:Cross Reactions; D004196:Disease Outbreaks; D000939:Epitopes / Q000032:analysis*; D014644:Genetic Variation; D006385:Hemagglutination Inhibition Tests; D006389:Hemagglutinins, Viral / Q000032:analysis*; D006801:Humans; D007114:Immunization; D009981:Influenza B virus / Q000276:immunology* / Q000302:isolation & purification; D007251:Influenza, Human / Q000382:microbiology; D011817:Rabbits; D051381:Rats; D013045:Species Specificity
chemical_list: D000939:Epitopes; D006389:Hemagglutinins, Viral
vernacular_title: Novye shtammospetsificheskie determinanty v gemaggliutininakh virusov grippa B, izolirovannykh v 1983-1984 gg.