Keratinocyte T6 antigen expression after PUVA therapy.
We report T6 antigen expression on keratinocytes in 11 cutaneous T lymphomas treated by PUVA therapy. This staining was absent before treatment. T6 reactivity was strictly limited to cell membrane. The nature of this expression is discussed, and it is suggested that it could be attributed to a passive diffusion from Langerhans's cells.
D000911:Antibodies, Monoclonal; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis*; D000078404:Epidermal Cells; D004817:Epidermis / Q000276:immunology*; D006684:HLA-DR Antigens / Q000032:analysis; D006801:Humans; D007633:Keratins; D007958:Leukocyte Count; D008223:Lymphoma / Q000188:drug therapy* / Q000276:immunology; D011701:PUVA Therapy / Q000009:adverse effects*; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000276:immunology; D013601:T-Lymphocytes; D006377:T-Lymphocytes, Helper-Inducer; D050378:T-Lymphocytes, Regulatory
D000911:Antibodies, Monoclonal; D000945:Antigens, Differentiation, T-Lymphocyte; D006684:HLA-DR Antigens; D007633:Keratins