Susceptibility to mercurials of clinical Pseudomonas aeruginosa isolated in México.
Susceptibility to inorganic mercuric ions and to organomercurials of 237 Pseudomonas aeruginosa clinical strains isolated in Mexico was determined by agar dilution tests. Resistant strains fell into two classes: i) narrow-spectrum resistant strains (27% of total isolates) resistant only to mercuric ions and to merbromin, and most grouped in pyocin type 1; and ii) broad-spectrum resistant strains (5%) with additional resistances to thimerosal, phenylmercury, methylmercury and p-hydroxymercuribenzoate, that belonged mostly to pyocin type 10. Mercurial resistant isolates showed a higher proportion of resistance to antibiotics and metals than did mercurial sensitive isolates, and broad-spectrum resistant strains had the highest frequency of resistance to antibiotics and to tellurite and arsenate.
D006801:Humans; D006902:Hydroxymercuribenzoates / Q000494:pharmacology; D008622:Merbromin / Q000494:pharmacology; D008627:Mercuric Chloride / Q000494:pharmacology; D008628:Mercury / Q000494:pharmacology*; D008767:Methylmercury Compounds / Q000494:pharmacology; D010662:Phenylmercuric Acetate / Q000494:pharmacology; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D013849:Thimerosal / Q000494:pharmacology
D006902:Hydroxymercuribenzoates; D008767:Methylmercury Compounds; C030601:4-hydroxymercuribenzoate; D013849:Thimerosal; D008627:Mercuric Chloride; D008628:Mercury; D008622:Merbromin; D010662:Phenylmercuric Acetate; C004925:methylmercuric chloride