Complete recovery of pure red cell aplasia by intramuscular gammaglobulin therapy in a child with hypoparathyroidism.
A 10-year-old girl with multiple endocrinopathies, hypoparathyroidism, and pernicious anemia subsequently developed pure red cell aplasia, which responded only temporarily to cytotoxic therapy. Because of transfusion dependency, resistance to steroids, plasmapheresis, and Cytoxan, she was given injections of intramuscular gammaglobulin. The injections caused a prompt and sustained rise in the child's erythropoiesis.
D002648:Child; D005260:Female; D006801:Humans; D007011:Hypoparathyroidism / Q000150:complications / Q000276:immunology / Q000628:therapy*; D007116:Immunization, Passive; D007136:Immunoglobulins / Q000032:analysis; D007273:Injections, Intramuscular; D012010:Red-Cell Aplasia, Pure / Q000150:complications / Q000276:immunology / Q000628:therapy*; D013601:T-Lymphocytes / Q000276:immunology; D005719:gamma-Globulins / Q000008:administration & dosage*
D007136:Immunoglobulins; D005719:gamma-Globulins