title: [Primary lymphoma of the nervous system following radiculoneuritis caused by Borrelia burgdorferi: study of a case].
abstract: A 50-year-old man had a primary lymphoma of the central nervous system one year after a tick bite and a radiculoneuritis secondary to Borrelia burgdorferi infection. Determination of antibodies against Borrelia burgdorferi revealed increasing IgM and IgG titers, and the autopsy showed a primary B-cell immunoblastic lymphoma of the brain without evidence of extraneural lymphoproliferative disorder. Lymphoma of the brain is a rare type of central nervous system cancer, and sporadic cases appear without predisposing features such as immunosuppression or viral infection. The controversy surrounding the histogenesis of this neoplasm is reviewed: an unknown agent or a cofactor should provoke cellular proliferation and the formation of a lymphoma.
mesh_terms: D000818:Animals; D001733:Bites and Stings / Q000150:complications; D001899:Borrelia Infections / Q000473:pathology*; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007075:Immunoglobulin M / Q000378:metabolism; D008223:Lymphoma / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D011129:Polyradiculoneuropathy / Q000473:pathology*; D013987:Ticks; D014057:Tomography, X-Ray Computed
chemical_list: D007075:Immunoglobulin M
vernacular_title: Lymphome primaire du système nerveux après radiculonévrite à Borrelia burgdorferi: étude d'une observation.