[Phagocytic reactivity of granulocytes in the peripheral blood of patients with multiple sclerosis and normal probands].
For estimation of phagocytic activity the uptake by granulocytes of heat-inactivated, opsonised yeast particles (Saccharomyces cerevisiae) was measured. Peripheral granulocytes of multiple sclerosis patients revealed an enhanced ability for phagocytosis in comparison to normal healthy controls, if tested with normal serum as opsonic source. An activated state of cells in multiple sclerosis is supposed. The selective influence on granulocyte phagocytosis of treatment by ultraviolet-irradiated blood in multiple sclerosis patients supports the view of altered reactivity of these cells in comparison to normal controls.
Lehmitz
R
R
Abteilung Neurologie, Bereiches Medizin, Wilhelm-Pieck-Universität Rostock.
Mix
E
E
Jenssen
H L
HL
D000936:Antigen-Antibody Complex / Q000276:immunology; D006801:Humans; D009103:Multiple Sclerosis / Q000276:immunology*; D004676:Myelin Basic Protein / Q000276:immunology; D009504:Neutrophils / Q000276:immunology*; D010587:Phagocytosis
D000936:Antigen-Antibody Complex; D004676:Myelin Basic Protein
Phagozytoseaktivität von Granulozyten aus dem peripheren Blut bei Patienten mit Multipler Sklerose und Normalprobanden.