title: Comparison of antigen immunoassay and reverse transcriptase assay for monitoring human immunodeficiency virus infection in an antiviral trial.
abstract: We compared the Abbott enzyme immunoassay for human immunodeficiency virus (HIV) antigen with the reverse transcriptase assay (RTA) as a means of monitoring HIV infection during an antiviral trial. The Abbott enzyme immunoassay detected HIV earlier than RTA whether or not the patients were antigenemic and appears to be superior to RTA for detecting HIV in cultures used for monitoring clinical trials.
authors: Department of Medicine, State University of New York, Stony Brook 11794.
authors: H
authors: H
authors: Burger
authors: D
authors: D
authors: Paul
authors: F P
authors: FP
authors: Siegal
authors: I
authors: I
authors: Wendel
authors: S
authors: S
authors: Neff
authors: D
authors: D
authors: Eilbott
authors: K
authors: K
authors: Gehan
authors: R
authors: R
authors: Grimson
authors: B
authors: B
authors: Weiser
mesh_terms: D000386:AIDS-Related Complex / Q000188:drug therapy / Q000382:microbiology*; D000998:Antiviral Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006678:HIV / Q000201:enzymology*; D015488:HIV Antigens / Q000032:analysis*; D006801:Humans; D007124:Immunoenzyme Techniques; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism*; D017828:Rifabutin; D012294:Rifamycins / Q000627:therapeutic use
chemical_list: D000998:Antiviral Agents; D015488:HIV Antigens; D012294:Rifamycins; D017828:Rifabutin; D012194:RNA-Directed DNA Polymerase