Amniotic fluid alpha-fetoprotein and acetylcholinesterase measurements in pregnancies associated with gastroschisis.
In this study we define for the first time the distribution of alpha-fetoprotein levels and acetylcholinesterase ratios in amniotic fluid samples associated with fetal gastroschisis. Elevated alpha-fetoprotein levels and positive acetylcholinesterase measurements are found in virtually all cases, indicating that these combined measurements are highly reliable in detecting this lesion.
Goldfine
C
C
Foundation for Blood Research, Scarborough, ME 04074.
Haddow
J E
JE
Knight
G J
GJ
Palomaki
G E
GE
D000009:Abdominal Muscles / Q000002:abnormalities*; D000110:Acetylcholinesterase / Q000032:analysis*; D000649:Amniocentesis; D000653:Amniotic Fluid / Q000032:analysis*; D002091:Butyrylcholinesterase / Q000032:analysis; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome; D013270:Stomach / Q000002:abnormalities*; D000509:alpha-Fetoproteins / Q000032:analysis*
D000509:alpha-Fetoproteins; D000110:Acetylcholinesterase; D002091:Butyrylcholinesterase