Cytomembrane-sandwiching in human epidermal Langerhans cells: a novel reaction to an irritant.
Relatively mild exposure of human epidermis to sodium lauryl sulphate caused a general activation of the Langerhans cell system within 5 hours. An unexpected reactive phenomenon was that this irritant caused some cytomembrane parts to fold upon each other, thereby forming numerous Birbeck granules, several of which had an irregular shape. Spotty cytomembrane damage to the Langerhans cells was also observed.
Mikulowska
A
A
Department of Medical Cell Research, University of Lund, Sweden.
Andersson
A
A
Bartosik
J
J
Falck
B
B
D000279:Administration, Cutaneous; D000328:Adult; D002462:Cell Membrane / Q000187:drug effects; D003594:Cytoplasmic Granules / Q000187:drug effects; D006801:Humans; D007509:Irritants / Q000009:adverse effects*; D007801:Langerhans Cells / Q000187:drug effects* / Q000473:pathology; D012967:Sodium Dodecyl Sulfate / Q000009:adverse effects*
D007509:Irritants; D012967:Sodium Dodecyl Sulfate