Effect of pentosan polysulphate in minipigs with experimental pulmonary emboli.
As a result of treatment with pentosan polysulphate in minipigs with experimental pulmonary emboli a decrease in mean pulmonary arterial pressure, an increase in blood flow of pulmonary artery and an increase in plasminogen activator was seen, compared with control animals who received saline infusion only.
Sedlarik
K
K
Center of Heart and Lung Diseases, Bad Berka, GDR.
Klöcking
H P
HP
Mönch
C
C
D000818:Animals; D001783:Blood Flow Velocity / Q000187:drug effects; D002496:Central Venous Pressure / Q000187:drug effects; D005260:Female; D008297:Male; D010426:Pentosan Sulfuric Polyester / Q000494:pharmacology*; D010960:Plasminogen Activators / Q000097:blood; D011134:Polysaccharides / Q000494:pharmacology*; D011655:Pulmonary Embolism / Q000097:blood / Q000209:etiology / Q000503:physiopathology*; D011669:Pulmonary Wedge Pressure / Q000187:drug effects; D013552:Swine; D013556:Swine, Miniature
D011134:Polysaccharides; D010426:Pentosan Sulfuric Polyester; D010960:Plasminogen Activators