Hemodialysis and the acute-phase response in chronic uremic patients.
In comparison with healthy persons, chronic uremic patients on regular hemodialysis treatment had significantly higher blood serum concentrations of alpha 1-acid glycoprotein, ceruloplasmin and C4 complement component, while levels of haptoglobin, C3 and transferrin were lower. Serum alpha 2-macroglobulin and alpha 1-antitrypsin levels were similar in both groups. Hemodialysis with cuprophan membrane induced only slight changes in some of these glycoproteins during a 48-hour follow-up period. Seven hours after termination of hemodialysis slight, but significant, decreases in blood serum transferrin and alpha 1-antitrypsin concentrations were observed. Hemodialysis thus does not seem to induce a conspicuous acute-phase reaction.
Trznadel
K
K
2nd Department of Internal Medicine, WAM, Lódź, Poland.
Luciak
M
M
Paradowski
M
M
Kubasiewicz-Ujma
B
B
D000209:Acute-Phase Proteins / Q000032:analysis*; D000210:Acute-Phase Reaction / Q000209:etiology*; D000328:Adult; D005260:Female; D006801:Humans; D007249:Inflammation / Q000209:etiology*; D008297:Male; D006435:Renal Dialysis; D013997:Time Factors; D014511:Uremia / Q000628:therapy*
D000209:Acute-Phase Proteins