Cationic liposome-mediated transfection.
A lipid named DOTMA has been created that forms unilamellar liposomes which complex with DNA and RNA for the transfection of mammalian cells, including suspension cells and hybridomas.
Felgner
P L
PL
Vical, Inc., San Diego, California 92121.
Ringold
G M
GM
D004247:DNA / Q000235:genetics; D008081:Liposomes; D000644:Quaternary Ammonium Compounds; D012313:RNA / Q000235:genetics; D014162:Transfection
D008081:Liposomes; D000644:Quaternary Ammonium Compounds; C054005:N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium; D012313:RNA; D004247:DNA