title: Biological effect of alkoxymethylene trimethylammonium chlorides on yeast Saccharomyces cerevisiae.
abstract: Six compounds of the group of quaternary ammonium salts have been tested for their biological activity using yeasts as a biological system. They have an inhibitory effect on respiration, cell growth and amino acid transport. A destroying action on protoplast regeneration and respiration has been also observed. The studied chemicals appear to have very pleiotropic action, focused on a damage of mitochondrial and cell plasma membranes.
authors: Department of Genetics, Wrocław University, Poland.
authors: J
authors: J
authors: Skała
authors: G
authors: G
authors: Orłowska-Matuszewska
authors: M
authors: M
authors: Misiewicz
authors: M
authors: M
authors: Oświecimska
authors: S
authors: S
authors: Witek
authors: Z
authors: Z
authors: Kotylak
mesh_terms: D000596:Amino Acids / Q000378:metabolism; D001692:Biological Transport / Q000187:drug effects; D002462:Cell Membrane / Q000187:drug effects; D008928:Mitochondria / Q000187:drug effects; D010101:Oxygen Consumption / Q000187:drug effects; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*; D012441:Saccharomyces cerevisiae / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure
chemical_list: D000596:Amino Acids; D000644:Quaternary Ammonium Compounds