[Chromoendoscopic study of the gastric mucosa].
Chromoendoscopy is an intravital endoscopic mucosa dyeing method. Chromoendoscopical methods suitable for examination of gastric mucosa are described including the steps of premedication as well as the steps of Congo-red and methylene-blue tests. The Congo-red test is capable of estimating the extent of acid-secreting area of gastric mucosa. Large acid secreting areas were found in four-fifth of duodenal ulcer patients with the Congo-red test. An equal ratio of small and large acid-secreting areas was found in gastric ulcer patients. The extent of acid-secreting area decreased parallely with the increase of mucosal atrophy in chronic gastritis patients. Methylene-blue test is suitable for detecting mucosal areas containing intestinal metaplasia and cancer. Intestinal metaplasia was detected histologically in 80% of cases containing mucosal areas stained by methylene-blue test. According to the authors' observations chromoendoscopy is a time consumptive additional method, which requires careful premedication and accurate endoscopic technique. Chromoendoscopy is suitable to detect the accurate places of mucosal biopsies therefore it seems to be a valuable element of morpho-functional diagnostic methods.
Rácz
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Tóth
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D003224:Congo Red; D005753:Gastric Mucosa / Q000473:pathology*; D005773:Gastroscopy / Q000379:methods; D006801:Humans; D008751:Methylene Blue; D013194:Staining and Labeling; D013272:Stomach Diseases / Q000175:diagnosis* / Q000473:pathology; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000473:pathology
D003224:Congo Red; D008751:Methylene Blue
A gyomornyálkahártya chromoendoscopiás vizsgálata.