title: [Control of anticoagulant therapy by using soluble thromboplastin].
abstract: The characteristics of soluble thromboplastin, a new coagulant agent, were under study. This drug is a high-molecular lipoprotein complex of human cadaver brain, purified by gel chromatography. The new preparation has been standardized and compared to thromboplastin preparations manufactured in this country and abroad. Soluble thromboplastin has been found fairly sensitive to reductions of the prothrombin factors levels, it may be used for monitoring the efficacy of indirect anticoagulant therapy, and conforms to WHO regulations for thromboplastin reference agents; this latter fact recommends this new drug as a thromboplastin reference agent in this country.
authors: A V
authors: AV
authors: Gaĭda
authors: V A
authors: VA
authors: Monastyrskiĭ
authors: Iu V
authors: IuV
authors: Magerovskiĭ
authors: Zh N
authors: ZhN
authors: Torik
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D001921:Brain; D006801:Humans; D008991:Monitoring, Physiologic / Q000379:methods; D011517:Prothrombin Time; D012995:Solubility; D013925:Thromboplastin / Q000592:standards; D013927:Thrombosis / Q000097:blood / Q000188:drug therapy*; D014020:Tissue Extracts; D014586:USSR
chemical_list: D000925:Anticoagulants; D014020:Tissue Extracts; D013925:Thromboplastin
vernacular_title: Kontro'l antikoaguliantnoĭ terapii pri pomoshchi preparata "tromboplastin rastvorimyĭ".