title: [Immunologic response to inflammation and trauma in children].
abstract: Inflammation and injury influence plasma proteins and immunoglobulins. They respond to noxious agents by a rise of c-reactive protein (CRP), orosomucoid, fibrinogen, haptaglobulin, alpha-1 antitrypsin, ceruloplasmin, C 3 and C 4 components of complement. The rate of rise and return to normal values varies. CRP reacts most'promptly. The following substances react by a decline of the levels: albumin, prealbumin, transferrin, alpha-1 lipoprotein and immunoglobulins. Investigation of the patient's immunological state is of prognostic value. CRP, orosomucoid, albumin and prealbumin are considered the most valuable indicators; from their values the so-called PINI index can be calculated and the patients can be divided into five prognostic zones. To threatened patients all-round care must be devoted incl. aimed provision of ATB and immunoprotective substances.
authors: H
authors: H
authors: Hájková
authors: M
authors: M
authors: Kudlácková
authors: J
authors: J
authors: Nováková
mesh_terms: D000209:Acute-Phase Proteins / Q000032:analysis; D002097:C-Reactive Protein / Q000032:analysis; D002648:Child; D003165:Complement System Proteins / Q000032:analysis; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007239:Infections / Q000097:blood / Q000276:immunology*; D008297:Male; D014947:Wounds and Injuries / Q000097:blood / Q000276:immunology*
chemical_list: D000209:Acute-Phase Proteins; D007136:Immunoglobulins; D003165:Complement System Proteins; D002097:C-Reactive Protein
vernacular_title: Immunologická odpovĕd na zánĕt a trauma u détí.