Family history of alcoholism in violent offenders and impulsive fire setters.
Fifty-six of 58 violent offenders and impulsive fire setters fulfilled the DSM-III criteria for alcohol abuse. Information necessary for evaluation of family history of alcoholism was obtained on 54 subjects. Forty-four of the 54 subjects had first- or second-degree blood relatives with alcoholism. Thirty-five had alcoholic fathers. Subjects with alcoholic fathers had a lower mean cerebrospinal fluid 5-hydroxyindoleacetic acid concentration and were more often impulsive than subjects without alcoholic fathers.
Linnoila
M
M
Laboratory of Clinical Studies, DICBR, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Md 20892.
De Jong
J
J
Virkkunen
M
M
D000328:Adult; D000437:Alcoholism / Q000235:genetics* / Q000523:psychology; D003417:Criminal Psychology; D007174:Disruptive, Impulse Control, and Conduct Disorders / Q000235:genetics*; D005220:Fathers / Q000523:psychology; D005260:Female; D005391:Firesetting Behavior / Q000134:cerebrospinal fluid / Q000235:genetics*; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000134:cerebrospinal fluid; D007175:Impulsive Behavior / Q000134:cerebrospinal fluid / Q000235:genetics*; D008297:Male; D012737:Sex Factors; D014754:Violence
D006897:Hydroxyindoleacetic Acid