Relationship between serum-amylase activity and intraductal pressures in the rat parotid and submandibular salivary glands after administration of pilocarpine or isoprenaline.
Ligation of the parotid ducts induced marked elevation of serum-amylase activity after administration of pilocarpine or isoprenaline. Secretion of saliva and serum-amylase activity increased most rapidly in the first 15 min after injection of pilocarpine, whereas isoprenaline induced a constant rate of secretion and serum-amylase activity over 120 min. Amylase activity in the serum was closely connected with intraductal pressure due to saliva secretion.
Ikeno
T
T
Department of Oral Biochemistry, Tohoku Dental University, Koriyama, Japan.
Ikeno
K
K
Uno
T
T
D000681:Amylases / Q000097:blood*; D000818:Animals; D007545:Isoproterenol / Q000494:pharmacology*; D008026:Ligation; D010306:Parotid Gland / Q000187:drug effects* / Q000201:enzymology / Q000502:physiology; D010862:Pilocarpine / Q000494:pharmacology*; D011312:Pressure; D051381:Rats; D011919:Rats, Inbred Strains; D012472:Salivation / Q000187:drug effects; D013363:Submandibular Gland / Q000187:drug effects* / Q000201:enzymology / Q000502:physiology
D010862:Pilocarpine; D000681:Amylases; D007545:Isoproterenol