title: Physiologic mucosal changes within the nose and ethmoid sinus: imaging of the nasal cycle by MRI.
abstract: Magnetic resonance studies frequently demonstrate increased T2-weighted signal in the nasal area. To further evaluate this phenomenon, several MRI examinations of the nasal cavity were performed within an 8- to 12-hour period. The study demonstrated that changes alternated from side to side and were interrupted by the administration of topical vasoconstriction, confirming imaging of the normal nasal cycle. Changes were also observed within the ethmoid sinuses. Signal intensity on T2-weighted images during the congested phase was similar to inflammatory mucosa. Occasionally, these changes make interpretation of the extent of pathology difficult in patients with sinus disease, and raise the possibility of inflammatory pathology in asymptomatic patients. Awareness of MRI imaging of nasal cycle should reduce the likelihood of diagnostic errors and provides another method for study of this physiologic phenomenon.
authors: Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, MD.
authors: D W
authors: DW
authors: Kennedy
authors: S J
authors: SJ
authors: Zinreich
authors: A J
authors: AJ
authors: Kumar
authors: A E
authors: AE
authors: Rosenbaum
authors: M E
authors: ME
authors: Johns
mesh_terms: D000328:Adult; D005005:Ethmoid Sinus / Q000033:anatomy & histology / Q000187:drug effects / Q000502:physiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009092:Mucous Membrane / Q000033:anatomy & histology / Q000187:drug effects / Q000502:physiology; D014663:Nasal Decongestants / Q000494:pharmacology; D009297:Nasal Mucosa / Q000033:anatomy & histology / Q000187:drug effects / Q000502:physiology*; D010507:Periodicity
chemical_list: D014663:Nasal Decongestants