[Autologous fibrin glue--a local hemostyptic agent following dental surgical interventions in patients undergoing anticoagulant therapy].
It could be proved that anticoagulants with direct and indirect effects, which are given in usual doses, do not have an influence on the concentration of fibrinogen and the activity of factor VIII in plasma and that consequently same conditions exist for the preparation of the autologous fibrin adhesive in patients treated with anticoagulants as in healthy probands. In 39 patients who are treated with anticoagulants a total of 69 teeth were extracted and autologous fibrin adhesive was used for haemostasis. Secondary bleeding which occurred in 5 patients could be stopped by resticking with autologous fibrin.
Leuthold
B
B
Bormann
R
R
D000925:Anticoagulants / Q000627:therapeutic use*; D007611:Aprotinin / Q000302:isolation & purification / Q000627:therapeutic use*; D004338:Drug Combinations / Q000302:isolation & purification / Q000627:therapeutic use; D004341:Drug Evaluation; D004347:Drug Interactions; D005176:Factor XIII / Q000302:isolation & purification / Q000627:therapeutic use*; D005260:Female; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen / Q000302:isolation & purification / Q000627:therapeutic use*; D006490:Hemostatics / Q000302:isolation & purification / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D013917:Thrombin / Q000302:isolation & purification / Q000627:therapeutic use*; D014081:Tooth Extraction
D000925:Anticoagulants; D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D006490:Hemostatics; D005340:Fibrinogen; D005176:Factor XIII; D007611:Aprotinin; D013917:Thrombin
Autologer Fibrinkleber--lokales Hämostyptikum nach stomatologisch-chirurgischen Eingriffen bei Patienten, die unter Antikoagulantien-therapie stehen.