UH series of monoclonal antibodies recognizing major histocompatibility complex class II antigen(s) of Japanese monkeys (Macaca fuscata).
Six mouse monoclonal antibodies were developed by immunization with a Japanese monkey cell line. These monoclonal antibodies, designated the UH series, reacted with large populations of peripheral B cells and monocytes, but not with T cells. The distribution of reactivities and the molecular weight of the membrane antigens recognized were similar to those of the HLA-DR monoclonal antibody; one inhibited the binding of HLA-DR. Human interferon-gamma induced increased expressions of all the UH antigen epitopes.
Murayama
Y
Y
Primate Research Institute, Kyoto University, Aichi, Japan.
Ishida
T
T
Hashiba
K
K
Noguchi
A
A
Takenaka
O
O
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D015153:Blotting, Western; D002427:Cebidae; D002460:Cell Line; D003429:Cross Reactions; D000939:Epitopes / Q000276:immunology; D005434:Flow Cytometry; D005455:Fluorescent Antibody Technique; D006684:HLA-DR Antigens / Q000276:immunology; D000882:Haplorhini; D000949:Histocompatibility Antigens Class II / Q000032:analysis / Q000276:immunology*; D006801:Humans; D007371:Interferon-gamma / Q000276:immunology; D007962:Leukocytes / Q000276:immunology; D008251:Macaca / Q000276:immunology*; D008970:Molecular Weight; D008971:Moles; D009000:Monocytes / Q000276:immunology; D011443:Strepsirhini
D000911:Antibodies, Monoclonal; D000939:Epitopes; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II; D007371:Interferon-gamma