title: [Estimate of the dose of chlorinated pesticides consumed daily by the Italian population (1978-1984)].
abstract: This work reports an estimate of the doses of chlorinated pesticides taken with a total diet by the Italian population in the period 1978-84. Previous researches, carried out in 1971-72, had regarded both uncooked and cooked diets, ready for the consumption. It was found that the amount of the considered pesticides taken in total (HCB, gamma-BHC and total-BHC, Aldrin/Dieldrin, Heptachlor/Heptachlor-epoxide and DDT total-equivalent) calculated as a sum of the percentage of each acceptable daily intake (A.D.I.), at that time recommended was near the limit of acceptability (98.5% for cooked diets and 107.0% for uncooked diets). In addition it was found that nearly the 40% of the dose assumed in all came from milk and its derivates (butter, cheese). Then considering the contribution of milk and derivates to the amount of pollutants assumed with a total diet, a new evaluation has been done, with regard to the period 1978-84, i.e. after the prohibition of the use of these pesticides in Italy and in other industrialized countries. Then the data have been processed, with regard to 211 samples of foods (90 of milk, 45 of cheese, 76 butter) coming from determinations carried out by the Multizonal Laboratory of Hygiene and Prevention of Ferrara, Milano, Udine, Bolzano, Trento, Pescara and from the Institute of Hygiene of Rome University "La Sapienza" in the period mentioned. Furthermore, alimentary consumptions of milk, butter and cheese in 1978-84 have been evaluated, and amounts of chlorinated pesticides taken with these foods have been calculated. Finally the dose taken with these foods has been extrapolated to a total diet. It has come out that the doses (estimated) taken with the total diet have notably decreased between 1971-72 and 1978-84. An anomaly is yet represented by HCB: while the quantity taken with food has decreased from 1971-72 to 1978-84 (from 3.7 to 1.3 micrograms/man/day), the concentrations in human adipose tissues have increased (from 1.02 to 1.99 mg/Kg). It can reasonably mean that assumption of HCB is not prevalently alimentary, but that it is due to other factors of environmental contamination. The data of the doses of chlorinated pesticides taken have also been compared with the respective ADI indicated in 1971-72 and in 1978-84.
authors: V
authors: V
authors: Leoni
authors: I
authors: I
authors: Camoni
authors: G
authors: G
authors: Puccetti
authors: A
authors: A
authors: Di Muccio
authors: L
authors: L
authors: Fabiani
mesh_terms: D000818:Animals; D002079:Butter / Q000032:analysis; D002611:Cheese / Q000032:analysis; D003634:DDT / Q000032:analysis; D005506:Food Contamination / Q000032:analysis*; D006581:Hexachlorobenzene / Q000032:analysis; D006801:Humans; D007306:Insecticides / Q000032:analysis*; D007558:Italy; D008892:Milk / Q000032:analysis
chemical_list: D007306:Insecticides; D006581:Hexachlorobenzene; D002079:Butter; D003634:DDT
vernacular_title: Una stima della dose di pesticidi clorurati assunta quotidianamente dalla popolazione italiana (1978-84).