[Characteristics of the silver-stained nucleoli in blast elements of various diameters from patients with acute leukemia].
Using silver staining, a study was made of the activity of ribosomal cistrons (RC) in proliferating and non-proliferating subpopulations of bone marrow and peripheral blood blasts, taken from 33 patients with acute non-lymphoblastic leukemia and from 17 patients with acute lymphoblastic leukemia. All the blasts including non-proliferating ones were revealed to synthesize ribosomal RNA (rRNA). The RC activity of large blasts was higher than that of small ones. A significant difference (P less than 0.01) in RC activity between lymphoid and non-lymphoid blasts was found. The relation between nucleolar organizer activity of blasts and their proliferating potentials is discussed, in addition to a possibility for practical use of the above mentioned data.
Mamaev
N N
NN
Martinez
H
H
Morozova
E O
EO
Ivanova
N A
NA
D001853:Bone Marrow / Q000648:ultrastructure; D002466:Cell Nucleolus / Q000648:ultrastructure*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000097:blood*; D008214:Lymphocytes / Q000648:ultrastructure*; D009697:Nucleolus Organizer Region / Q000648:ultrastructure; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000097:blood*; D012835:Silver Nitrate; D013194:Staining and Labeling / Q000379:methods
D012835:Silver Nitrate
Kharakteristika okrashennykh serebrom iadryshek v blastnykh élementakh raznogo diametra bol'nykh ostrymi leĭkozami.