[Substance P: a peripheral inhibitor of gastric acid secretion in the rat].
The inhibition of some peptidases in the central nervous system induces a decrease in gastric acid secretion. The present experiments indicate that substance P is not likely a candidate to mediate this effect in rats. Substance P, indeed, potently inhibits gastric acid secretion, but this effect appears mainly peripheral.
Rozé
C
C
Chicau-Chovet
M
M
D000818:Animals; D005744:Gastric Acid / Q000378:metabolism*; D005750:Gastric Juice / Q000187:drug effects*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013373:Substance P / Q000494:pharmacology*
D013373:Substance P
La substance P: un inhibiteur periphérique de la sécrétion gastrique acide chez le rat.