Infection of multipotent IL-3-dependent stem cells with a retroviral vector containing the IL-3 gene confers density-dependent growth autonomy without blocking differentiation.
Just
U
U
Paterson Institute for Cancer Research, Christie Hospital and Holt Radium Institute, Manchester, United Kingdom.
Spooncer
E
E
Katsuno
M
M
Hampson
I
I
Dexter
M
M
DeLamarter
J F
JF
Stocking
C
C
Kluge
N
N
Ostertag
W
W
D000818:Animals; D001854:Bone Marrow Cells; D002452:Cell Count; D002454:Cell Differentiation; D002455:Cell Division; D002478:Cells, Cultured; D003114:Colony-Forming Units Assay; D004247:DNA / Q000032:analysis; D015194:Diffusion Chambers, Culture; D015870:Gene Expression; D005822:Genetic Vectors / Q000502:physiology*; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D007377:Interleukin-3 / Q000096:biosynthesis / Q000235:genetics*; D051379:Mice; D012313:RNA / Q000032:analysis; D012190:Retroviridae / Q000235:genetics*
D007377:Interleukin-3; D012313:RNA; D004247:DNA