Diagnostic value of immunoreactive phospholipase A2 in acute pancreatitis.
In a prospective clinical trial 85 patients with acute pancreatitis were analysed for serum total amylase, pancreatic amylase, pancreatic lipase, trypsin, elastase 1, and immunoreactive phospholipase A2 (IR-PLA2). The diagnostic sensitivity of serum IR-PLA2 was comparable to that of serum total amylase, pancreatic amylase, and trypsin. The specificity of IR-PLA2 is superior to that of serum total amylase determination due to the fact that the IR-PLA2 determination is based on an antibody against human pancreatic PLA2.
Malfertheiner
P
P
Department of Gastroenterology, University of Ulm.
Nevalainen
T
T
Uhl
W
W
Schädlich
H
H
Büchler
M
M
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000437:Alcoholism / Q000150:complications; D000681:Amylases / Q000097:blood; D002769:Cholelithiasis / Q000150:complications; D005260:Female; D015200:Fluoroimmunoassay; D006801:Humans; D008049:Lipase / Q000097:blood; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000175:diagnosis* / Q000201:enzymology; D010740:Phospholipases / Q000097:blood*; D010741:Phospholipases A / Q000097:blood*; D054467:Phospholipases A2; D014357:Trypsin / Q000097:blood
D010740:Phospholipases; D008049:Lipase; D010741:Phospholipases A; D054467:Phospholipases A2; D000681:Amylases; D014357:Trypsin