Cutaneous squamous cell carcinoma with mucinous metaplasia.
A case of superficially invasive well-differentiated cutaneous squamous cell carcinoma containing numerous mucin-producing cells both within the epidermal and dermal components is reported. Histological, histochemical and immunohistochemical overlap exists between these cells and those of extramammary Paget's disease. The presence of mucinous metaplasia within this tumor supports an intraepidermal origin for extramammary Paget's disease.
Friedman
K J
KJ
Department of Dermatology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21205.
Hood
A F
AF
Farmer
E R
ER
D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000378:metabolism / Q000473:pathology*; D004817:Epidermis / Q000378:metabolism / Q000473:pathology; D005153:Facial Neoplasms / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007633:Keratins; D008297:Male; D008679:Metaplasia / Q000473:pathology; D008875:Middle Aged; D009077:Mucins / Q000096:biosynthesis; D013194:Staining and Labeling
D009077:Mucins; D007633:Keratins