title: Electrical oscillation and fluctuation in phospholipid membranes. Phospholipids can form a channel without protein.
abstract: Fluctuations and/or step-wise changes in membrane potential and electrical current were observed in bilayer membranes of dioleoylphosphatidylcholine (DOPC) in the absence of any channel protein. The DOPC membranes consisted of three types: black lipid membranes, pipette-clamp membranes and lipid membranes transferred to porous filter paper by conventional Langmuir-Blodgett techniques. This finding is significant since phospholipids are the main constituents of biomembranes. Lipid molecules with a cis double bond in their carbon skeleton are suggested to be important in the gating or excitation of biomembranes.
authors: College of General Education, University of Tokushima, Japan.
authors: K
authors: K
authors: Yoshikawa
authors: T
authors: T
authors: Fujimoto
authors: T
authors: T
authors: Shimooka
authors: H
authors: H
authors: Terada
authors: N
authors: N
authors: Kumazawa
authors: T
authors: T
authors: Ishii
mesh_terms: D004553:Electric Conductivity; D007473:Ion Channels / Q000502:physiology*; D008051:Lipid Bilayers; D008564:Membrane Potentials; D008954:Models, Biological; D010713:Phosphatidylcholines; D011506:Proteins
chemical_list: D007473:Ion Channels; D008051:Lipid Bilayers; D010713:Phosphatidylcholines; D011506:Proteins; C017251:1,2-oleoylphosphatidylcholine