title: [The relationship between the intracellular content of 1-methyl-3-isobutylxanthine and the permeability for water of the bladder wall in the frog].
abstract: The data obtained show a direct interrelationship between the concentration of MIBX in cells and an increase of osmotic permeability. The method of determination of intracellular concentration of the MIBX using [3H]-MIBX, was developed, and the way to obtain radioactive MIBX described. The used approach permits to take into consideration functional changes as related to the intracellular concentration of inhibiting agents.
authors: Iu V
authors: IuV
authors: Natochin
authors: R G
authors: RG
authors: Parnova
authors: D L
authors: DL
authors: Firsov
authors: E I
authors: EI
authors: Shakhmatova
authors: Iu L
authors: IuL
authors: Kaminskiĭ
mesh_terms: D015056:1-Methyl-3-isobutylxanthine / Q000494:pharmacology*; D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000037:antagonists & inhibitors; D000818:Animals; D002463:Cell Membrane Permeability / Q000187:drug effects / Q000502:physiology*; D000242:Cyclic AMP / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D009995:Osmosis / Q000187:drug effects; D011896:Rana temporaria; D013806:Theophylline / Q000031:analogs & derivatives*; D014316:Tritium; D001743:Urinary Bladder / Q000187:drug effects / Q000502:physiology*; D014867:Water / Q000378:metabolism*
chemical_list: D014867:Water; D014316:Tritium; D013806:Theophylline; D000242:Cyclic AMP; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D015056:1-Methyl-3-isobutylxanthine
vernacular_title: Zavisimost' mezhdy vnutrikletochnym soderzhaniem 1-metil-3-izobutilksantina i pronitsaemost'iu dlia vody stenki mochevogo puzyria liagushki.