Soybean agglutinin for detection of macrophages in Whipple's disease: a possible aid in diagnosis.
The lectin binding pattern of PAS-positive macrophages in Whipple's disease was examined with SBA, LPA, UEA I, PNA and WGA. All PAS-positive macrophages of Whipple's disease were SBA positive. Other macrophages and epitheloid cells, so far tested, did not react with SBA. This finding may be helpful in the diagnosis of Whipple's disease especially in lymph node biopsies, where the amount of PAS-positive macrophages usually is much lower than in intestinal biopsies.
Borisch
B
B
Pathologisches Institut, Universität Würzburg.
Schumacher
U
U
Kirchner
T
T
Müller-Hermelink
H K
HK
D006651:Histocytochemistry; D006801:Humans; D037102:Lectins; D008264:Macrophages / Q000032:analysis*; D037121:Plant Lectins; D030262:Soybean Proteins; D008061:Whipple Disease / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D010835:Phytohemagglutinins
D037102:Lectins; D037121:Plant Lectins; D030262:Soybean Proteins; C028824:soybean lectin; D010835:Phytohemagglutinins