Specific and shared antigenic components of Taenia saginata oncospheres.
Taenia saginata oncosphere components were analysed by double diffusion. Antigenic components in saline or detergent (Triton x-100) extracts of T saginata oncospheres were identified using a rabbit polyclonal serum directed against the oncosphere and compared with extracts prepared from the metacestodes and proglottids of T saginata and six other helminths commonly found in cattle. There were seven antigenic components found in the saline extract of the oncospheres, of which six were shared with the metacestodes and proglottids. None of these components was consistently different from those of the other six helminths. However, one of the four components in the detergent extract of the oncospheres was present in neither of the extracts of other stages of T saginata nor in extracts of other helminths. This may be of diagnostic significance.
Onyango-Abuje
J A
JA
Veterinary Research Department, Kikuyu, Kenya.
Waiyaki
P G
PG
Gathuma
J M
JM
D000818:Animals; D000947:Antigens, Helminth / Q000032:analysis* / Q000302:isolation & purification; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis; D003551:Cysticercosis / Q000175:diagnosis / Q000662:veterinary; D000939:Epitopes / Q000032:analysis; D006801:Humans; D007106:Immune Sera / Q000276:immunology; D005779:Immunodiffusion; D013621:Taenia / Q000276:immunology*
D000947:Antigens, Helminth; D000939:Epitopes; D007106:Immune Sera