[Decreased chemoreactivity of neurons of the sensorimotor cortex during adaptation to stress and its role in the prevention of heart fibrillation in acute ischemia].
The effect of the adaptation to repeated short-term stress on the bioelectrical responses of neurons in the IV layer of the sensorimotor cortex developed under the action of acetylcholine and norepinephrine was studied in rats along with the effects on the development of arrhythmias, fibrillation and mortality in conscious animals with cardiac ischemia. It has been established that the preliminary adaptation reduced considerably the chemoreactivity and especially adrenoreactivity of the neurons and at the same time decreased fibrillation and mortality in acute ischemia.
Meerson
F Z
FZ
Kruglikov
R I
RI
Diusenov
S S
SS
Markarova
M Iu
MIu
Koshtoiants
O Kh
OKh
D000109:Acetylcholine / Q000494:pharmacology; D000222:Adaptation, Physiological; D000818:Animals; D005117:Cardiac Complexes, Premature / Q000209:etiology / Q000517:prevention & control; D006352:Heart Ventricles; D007103:Immobilization; D008297:Male; D009044:Motor Cortex / Q000187:drug effects*; D009203:Myocardial Infarction / Q000401:mortality / Q000503:physiopathology*; D009474:Neurons / Q000187:drug effects*; D009638:Norepinephrine / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D013312:Stress, Physiological / Q000503:physiopathology*; D013610:Tachycardia / Q000209:etiology / Q000517:prevention & control; D013997:Time Factors; D014693:Ventricular Fibrillation / Q000209:etiology* / Q000517:prevention & control
D000109:Acetylcholine; D009638:Norepinephrine
Snizhenie khemoreaktivnosti neĭronov sensomotornoĭ kory pri adaptatsii k stressovym vozdeĭstviiam i rol' étogo iavleniia v preduprezhdenii fibrilliatsii serdtsa pri ostroĭ ishemii.