Alpha-fetoprotein and mediastinal germ cell tumors.
The Authors discuss the utility of alpha-fetoprotein (AFP) determination in mediastinal dysembryomas. AFP should be determined in all cases of mediastinal lesion. High levels of up to 500 ng/ml are a sure sign of germ cell tumors. An extremely high level (greater than 1,000 ng/ml) is an indication that the lesion is a mesoblastoma. An increase in the AFP level in the follow-up of patients affected by germ cell tumors is a sure sign of the recurrence of the disease.
Rapellino
M
M
Cellerino
A
A
Ardissone
F
F
Libertucci
D
D
Coni
F
F
Aimo
G
G
Pecchio
F
F
D006801:Humans; D008479:Mediastinal Neoplasms / Q000175:diagnosis*; D009373:Neoplasms, Germ Cell and Embryonal / Q000175:diagnosis*; D013724:Teratoma / Q000175:diagnosis*; D000509:alpha-Fetoproteins / Q000032:analysis*
D000509:alpha-Fetoproteins