[Ektacytometry: a method for characterizing erythrocyte deformability].
In principle, the ektacytometer consists of a combination of a Laser-illuminated diffractometer with a circular viscometric fluid flow, analogous to that of a rotation viscometer. In this device erythrocytes are deformed to ellipsoid-like shapes and produce a diffraction pattern which, depending on the flow conditions, is to some degree elliptically distorted. From the shape of this pattern the extent of cell deformation can be deduced. In this survey an introduction into the mode of operation of the ektacytometer as well as an overview on methodical variants are given on the basis of literature. Since its publication in 1974 ektacytometry has found many applications, mainly in basic research. Presumably, it will receive still broader interest also as a routine method in haematological or pharmaceutical laboratories.
Scheven
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Institut für Anatomie, Friedrich-Schiller-Universität Jena.
D004864:Equipment and Supplies; D004907:Erythrocyte Deformability; D006801:Humans; D007834:Lasers; D012212:Rheology
Ektazytometrie--ein Verfahren zur Charakterisierung der Deformierbarkeit von Erythrozyten.