title: Chromatin changes in frog neurons after eighth nerve transection.
abstract: Fourteen days after unilateral eighth nerve transection in the frog, Purkinje neurons of the lobus vestibulolateralis and corpus of the cerebellum and medium-sized neurons of the vestibular nuclear complex showed changes in metabolic activity. In the ipsilateral parts, and to a lesser extent in the contralateral parts, of operated frogs, the Feulgen-DNA values were higher and the nuclear areas larger, associated with decondensation of chromatin. The cytoplasmic basophilia was also less. These changes could be due to anabolic responses of the neuronal populations during regeneration. The anabolic reaction of the corpus cerebelli and contralateral vestibular nuclear complex is only partially non-specific and ascribable to the surgical trauma (comparison between sham-operated and unoperated frogs). The results indicate clear patterns of connection between the ipsilateral and contralateral parts and between the cerebellar and vestibular nuclear complex neurons.
authors: Centro di Studio per l'Istochimica del C.N.R., Universita' di Pavia, Italy.
authors: G
authors: G
authors: Bernocchi
authors: S
authors: S
authors: Giacometti
authors: E
authors: E
authors: Scherini
authors: P
authors: P
authors: Valli
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure; D002843:Chromatin / Q000648:ultrastructure*; D006652:Histological Techniques; D009474:Neurons / Q000502:physiology / Q000648:ultrastructure*; D011893:Rana esculenta / Q000502:physiology*; D013194:Staining and Labeling
chemical_list: D002843:Chromatin