title: The effect of sleep deprivation on the rate of focal interictal epileptiform discharges.
abstract: Eight men with complex partial seizures who had frequent focal interictal epileptiform discharges (FIEDs) during routine EEGs were selected for all-night EEG recording before, and after 36 h of sleep deprivation. After sleep deprivation 6 of 8 patients showed increased FIEDs. The pooled mean number of FIEDs was greatest during light non-REM stages of sleep, especially stage II. Thus sleep deprivation is an effective activation method in medicated patients with complex partial seizures. However, a significant activation requires recording stage II sleep after sleep deprivation.
authors: Department of Neurology, SUNY Health Science Center.
authors: M
authors: M
authors: Molaie
authors: A
authors: A
authors: Cruz
mesh_terms: D000328:Adult; D004569:Electroencephalography; D004827:Epilepsy / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012892:Sleep Deprivation