title: Inflammatory and immunomodulatory roles of TGF-beta.
abstract: Transforming growth factors (TGFs) are small polypeptides that were initially defined by their ability to induce transformation of non-neoplastic cells in culture. However, it has become increasingly clear that TGFs are not restricted in function to promoting cell growth. One type of transforming growth factor, TGF-beta, is a multifunctional molecule which has unique and potent effects on many target cells and tissues. In this article, Sharon Wahl, Nancy McCartney-Francis and Stephan Mergenhagen focus on the evolving role of TGF-beta in regulating inflammation, immune responses and tissue repair.
authors: S M
authors: SM
authors: Wahl
authors: N
authors: N
authors: McCartney-Francis
authors: S E
authors: SE
authors: Mergenhagen
mesh_terms: D000818:Animals; D007249:Inflammation / Q000209:etiology; D051379:Mice; D009389:Neovascularization, Pathologic; D015291:Transforming Growth Factors / Q000276:immunology*
chemical_list: D015291:Transforming Growth Factors