Mitotic activity of the endothelial vascular cell in the immature retina.
We studied the ultrastructural characteristics of the mitoses of the retinal vascular endothelium during normal vasculogenesis in the immature retina of 45 newborn albino rats, from birth to the end of the 1st month of postnatal development. For the first time mitotic phenomena in the endothelial cells to the adjacent endothelium during all mitosis stages. Direct budding from the pre-existing vessels seems to be the actual mechanism of growth of the retinal vessels in the holangiotic immature retina.
Alio y Sanz
J
J
Department of Ophthalmology, University of Alicante, Spain.
Ludeña
M
M
Millan
A A
AA
Garcia
S
S
Caballero
V
V
D000818:Animals; D000831:Animals, Newborn; D004730:Endothelium, Vascular / Q000166:cytology*; D007365:Intercellular Junctions / Q000648:ultrastructure; D008938:Mitosis; D009389:Neovascularization, Pathologic / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains; D012160:Retina / Q000098:blood supply*; D012171:Retinal Vessels / Q000254:growth & development* / Q000648:ultrastructure