Sudan black B positivity in acute lymphoblastic leukemia.
The records of 458 patients with acute lymphoblastic leukemia (ALL) have been reviewed. The diagnosis of ALL was based on clinical examination and morphological, cytochemical and immunophenotypic characteristics (20% or more blasts reacting with lymphoid monoclonal antibodies) of blood and/or bone marrow. Blast cells of 6 (1.3%) patients showed positive reaction with Sudan black B (SBB) in the absence of reactivity to any other myeloid markers. Positive reaction with SBB stain cannot be considered specific for myeloid series.
Charak
B S
BS
Department of Medical Oncology, Tata Memorial Hospital, Bombay, India.
Advani
S H
SH
Karandikar
S M
SM
Parikh
P M
PM
Nair
C N
CN
Das Gupta
A
A
Gopal
R
R
Tapan
K S
KS
Nadkarni
K S
KS
Kurkure
P A
PA
D000293:Adolescent; D000328:Adult; D001391:Azo Compounds; D002454:Cell Differentiation; D002471:Cell Transformation, Neoplastic / Q000032:analysis / Q000473:pathology; D002648:Child; D004396:Coloring Agents; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009281:Naphthalenes; D009195:Peroxidase; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000097:blood / Q000473:pathology*; D013194:Staining and Labeling / Q000379:methods
D001391:Azo Compounds; D004396:Coloring Agents; D009281:Naphthalenes; C016118:Sudan Black B; D009195:Peroxidase