Factitiously high sodium activities on the Ektachem 400 owing to interferences by high gamma-globulin concentrations.
Sera from patients with above-normal gamma-globulin concentrations give sodium values as much as 10% higher when measured in the Kodak Ektachem 400 analyzer than results obtained with the Beckman Astra-8 analyzer. Results obtained with the Astra were in agreement with flame photometry. A similar relative bias was observed for potassium measurement in the Ektachem. This discrepancy was corrected when we used a new generation of reference fluid provided by Kodak, which is currently available for general use.
Eastep
S J
SJ
Clinical Laboratories #812, Hennepin County Medical Center, Minneapolis, MN 55415.
Benson
P J
PJ
Preese
L M
LM
Apple
F S
FS
D000328:Adult; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008108:Liver Diseases, Alcoholic / Q000097:blood; D012964:Sodium / Q000097:blood*; D005719:gamma-Globulins / Q000032:analysis*
D005719:gamma-Globulins; D012964:Sodium