title: Comparison of a human T-cell lymphotropic virus type I strain from cerebrospinal fluid of a Jamaican patient with tropical spastic paraparesis with a prototype human T-cell lymphotropic virus type I.
abstract: The isolation and characterization of a human T-cell lymphotropic retrovirus related to human T-cell lymphotropic virus type I (HTLV-I) from cerebrospinal fluid of a Jamaican patient with tropical spastic paraparesis is described. The virus isolate is a typical type C retrovirus as seen by electron microscopy and is related to prototype HTLV-I isolated from patients with adult T-cell leukemia but is not identical to this prototype HTLV-I as seen by restriction enzyme mapping.
authors: Laboratory of Tumor Cell Biology, National Cancer Institute, Bethesda, MD 20892.
authors: P S
authors: PS
authors: Sarin
authors: P
authors: P
authors: Rodgers-Johnson
authors: D K
authors: DK
authors: Sun
authors: A H
authors: AH
authors: Thornton
authors: O S
authors: OS
authors: Morgan
authors: W N
authors: WN
authors: Gibbs
authors: C
authors: C
authors: Mora
authors: G
authors: G
authors: McKhann
authors: D C
authors: DC
authors: Gajdusek
authors: C J
authors: CJ
authors: Gibbs
mesh_terms: D000368:Aged; D002478:Cells, Cultured; D002555:Cerebrospinal Fluid / Q000382:microbiology*; D004262:DNA Restriction Enzymes; D004279:DNA, Viral / Q000032:analysis; D015480:Deltaretrovirus Antibodies / Q000032:analysis; D005260:Female; D005455:Fluorescent Antibody Technique; D015368:Human T-lymphotropic virus 1 / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D007563:Jamaica; D015458:Leukemia, T-Cell / Q000382:microbiology; D007963:Leukocytes, Mononuclear / Q000382:microbiology; D008854:Microscopy, Electron; D015493:Paraparesis, Tropical Spastic / Q000276:immunology / Q000382:microbiology*; D012194:RNA-Directed DNA Polymerase / Q000032:analysis
chemical_list: D004279:DNA, Viral; D015480:Deltaretrovirus Antibodies; D012194:RNA-Directed DNA Polymerase; D004262:DNA Restriction Enzymes