[Changes in histones and transcription in the nuclei of sympathetic neurons in rats of various ages under the action of testosterone].
A study of chromatin in KSTG neurocytes revealed the most remarkable changes of template activity after testosterone administration in 9 days old rats and less significant changes in adult rats. No changes were detected in 19 days old rats. The pattern of silver staining of the nuclei did not differ from the control in all age groups. The possible role of testosterone in differentiation of KSTG neurocytes in early postnatal period as well as the stage-related differences in mechanisms of the hormone action during ontogenesis are discussed.
Chernykh
G V
GV
Grigor'eva
A V
AV
Iarygin
V N
VN
D000375:Aging / Q000187:drug effects* / Q000502:physiology; D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects / Q000502:physiology; D002467:Cell Nucleus / Q000187:drug effects* / Q000648:ultrastructure; D005260:Female; D005728:Ganglia, Sympathetic / Q000187:drug effects* / Q000648:ultrastructure; D006657:Histones / Q000187:drug effects* / Q000648:ultrastructure; D009474:Neurons / Q000187:drug effects* / Q000648:ultrastructure; D009562:Nissl Bodies / Q000187:drug effects / Q000648:ultrastructure; D015530:Nuclear Matrix / Q000187:drug effects / Q000648:ultrastructure; D051381:Rats; D013194:Staining and Labeling / Q000379:methods; D013739:Testosterone / Q000494:pharmacology*; D014158:Transcription, Genetic / Q000187:drug effects* / Q000502:physiology
D006657:Histones; D013739:Testosterone
Izmenenie gistonov i transkriptsii v iadrakh simpaticheskikh neĭronov krys raznogo vozrasta pri deĭstvii testosterona.