title: [Temperature influence on human testicular function--optimal temperature for testicular macromolecular synthesis].
abstract: Precursor incorporations into DNA, RNA and protein fractions of the human testicular tissue were examined at 28 degrees C-43 degrees C in vitro to study the optimal temperature for DNA, RNA and protein synthesis in the human testis. The results suggest that the DNA synthesis shows delicate temperature sensitivity and is at a maximum at 31 degrees C, whereas the RNA and protein syntheses are at a maximum at 37 degrees C-40 degrees C. The slight variation of the testicular temperature may cause spermatogenic dysfunction because of delicate temperature sensitivity of the testicular DNA synthesis.
authors: M
authors: M
authors: Nakamura
authors: N
authors: N
authors: Nonomura
authors: M
authors: M
authors: Namiki
authors: A
authors: A
authors: Okuyama
authors: E
authors: E
authors: Koh
authors: N
authors: N
authors: Kondoh
authors: M
authors: M
authors: Takeyama
authors: H
authors: H
authors: Kiyohara
authors: H
authors: H
authors: Fujioka
mesh_terms: D046508:Culture Techniques; D004247:DNA / Q000096:biosynthesis*; D006801:Humans; D046911:Macromolecular Substances; D008297:Male; D014176:Protein Biosynthesis; D012313:RNA / Q000096:biosynthesis*; D013696:Temperature; D013737:Testis / Q000378:metabolism / Q000502:physiology*
chemical_list: D046911:Macromolecular Substances; D012313:RNA; D004247:DNA