title: Fibrin and fibronectin sealing system in a guided tissue regeneration procedure. A case report.
abstract: A case is reported showing an iatrogenic, chronic abscess of six years' duration associated with a bony defect between the maxillary right central and lateral incisors. The osseous defect was treated by a guided tissue regeneration procedure with the use of a fibrin and fibronectin sealing system. The system was employed to fix the membranes and keep them apart from the root surface, thereby maintaining room for bone regeneration. This operation resulted in a 9-mm clinical attachment gain and in an 11-mm filling of the osseous defect. The second surgical stage after a three-month reentry procedure was strictly for cosmetic improvement by means of a free gingival graft.
authors: Department of Periodontology, Dental School, University of Siena, Italy.
authors: G P
authors: GP
authors: Pini Prato
authors: P
authors: P
authors: Cortellini
authors: C
authors: C
authors: Clauser
mesh_terms: D000293:Adolescent; D000539:Alveolar Process / Q000502:physiology; D007611:Aprotinin / Q000627:therapeutic use*; D001862:Bone Resorption / Q000601:surgery; D004338:Drug Combinations / Q000627:therapeutic use; D005176:Factor XIII / Q000627:therapeutic use*; D005337:Fibrin / Q000627:therapeutic use*; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008851:Micropore Filters; D010508:Periodontal Abscess / Q000601:surgery*; D010518:Periodontitis / Q000601:surgery*; D010519:Periodontium / Q000502:physiology* / Q000601:surgery; D012038:Regeneration; D013524:Surgical Flaps; D013917:Thrombin / Q000627:therapeutic use*; D014014:Tissue Adhesives / Q000627:therapeutic use*; D014092:Tooth Root / Q000601:surgery
chemical_list: D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives; D005337:Fibrin; D005340:Fibrinogen; D005176:Factor XIII; D007611:Aprotinin; D013917:Thrombin