title: Functional deficits of central sensory and motor pathways in patients with cervical spinal stenosis: a study of SEPs and EMG responses to non-invasive brain stimulation.
abstract: The central conduction time of the descending and ascending fibers of the spinal cord were examined in patients with radiologically defined cervical spinal stenosis (antero-posterior diameter of the spinal canal less than 13 mm). Nineteen patients were examined, only 4 of whom showed clinical signs of spastic weakness or ataxia. The electromyographic response after non-invasive stimulation of the leg area of the motor cortex was delayed in 13 of the 15 clinically unaffected patients. The central latency (N21-P39) of the somatosensory evoked response after stimulation of the tibial nerve (tibialis SEP) was increased in 12 of the 15 individuals. The 4 patients with clinical signs showed abnormal latencies with both methods. The use of both techniques for the examination of the function of the spinal cord revealed increased latencies in the central motor and/or sensory pathways in all patients. The technique of non-invasive stimulation of the corticospinal system therefore provides an additional tool to detect and quantify subclinical and clinically apparent lesions in patients with defined cervical spinal stenosis.
authors: Department of Neurology, University of Münster, F.R.G.
authors: H
authors: H
authors: Masur
authors: C E
authors: CE
authors: Elger
authors: K
authors: K
authors: Render
authors: G
authors: G
authors: Fahrendorf
authors: A C
authors: AC
authors: Ludolph
mesh_terms: D002490:Central Nervous System / Q000503:physiopathology*; D004558:Electric Stimulation; D004576:Electromyography; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D006801:Humans; D007866:Leg / Q000503:physiopathology; D009044:Motor Cortex / Q000503:physiopathology; D011930:Reaction Time / Q000502:physiology; D013116:Spinal Cord / Q000503:physiopathology*; D013130:Spinal Stenosis / Q000503:physiopathology*; D013979:Tibial Nerve / Q000503:physiopathology