title: [Therapeutic aspects of hairy cell leukemia].
abstract: This work considers the new advances in hairy cell leukemia therapy. During the last decades the only useful treatments were splenectomy, or, in case of failure or relapse, various chemotherapeutic approaches. Sometimes leukapheresis, radiotherapy, androgens, allogenic bone marrow transplantation, corticosteroids and lithium salts were used with few good results. Interferon and 2-deoxicoformycin recently introduced for the treatment of HCL have determined a dramatic change in the outlook of this disease, producing a high percentage of complete and partial remission.
authors: F
authors: F
authors: Rosa
authors: S
authors: S
authors: Casciaro
authors: A M
authors: AM
authors: Gatti
authors: P
authors: P
authors: Boccaccio
authors: R
authors: R
authors: Ghio
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D003070:Coformycin / Q000031:analogs & derivatives / Q000627:therapeutic use*; D006801:Humans; D007372:Interferons / Q000627:therapeutic use*; D007943:Leukemia, Hairy Cell / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D015649:Pentostatin; D012263:Ribonucleosides / Q000627:therapeutic use*; D013156:Splenectomy
chemical_list: D000970:Antineoplastic Agents; D012263:Ribonucleosides; D003070:Coformycin; D015649:Pentostatin; D007372:Interferons
vernacular_title: Aspetti terapeutici dell'hairy cell leukemia.