Primary structure of a proteinase inhibitor released from goat serum inter-alpha-trypsin inhibitor.
An acid-resistant trypsin inhibitor was released from goat serum inter-alpha-trypsin inhibitor and isolated by affinity chromatography. The primary structure of the inhibitor was established and the inhibitory properties were estimated. The inhibitor designed gIK-14 was characterized as a serine proteinase inhibitor from the family of the double-headed Kunitz-type inhibitors as suggested.
Rasp
G
G
Biochemisches Labor der Klinik und Poliklinik für Hals-, Nasen- und Ohrenkranke, Universität Müchen, FRG.
Hochstrasser
K
K
Gerl
C
C
Wachter
E
E
D000510:Alpha-Globulins / Q000032:analysis*; D000595:Amino Acid Sequence; D000818:Animals; D002846:Chromatography, Affinity; D006041:Goats; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000032:analysis; D010447:Peptide Hydrolases; D011480:Protease Inhibitors / Q000097:blood*; D014361:Trypsin Inhibitors / Q000097:blood*
D000510:Alpha-Globulins; D010446:Peptide Fragments; D011480:Protease Inhibitors; D014361:Trypsin Inhibitors; C011877:inter-alpha-inhibitor; D010447:Peptide Hydrolases