title: Evidence that chicken CR1 elements represent a novel family of retroposons.
abstract: We report the first precise delineation of a chicken CR1 element and show that it is flanked by a 6-base-pair target site duplication that occurred when this repetitive element transposed. The 3' end of this CR1 element is defined by an 8-base-pair imperfect direct repeat, and we infer that this sequence represents the 3' end of all intact CR1 elements. In contrast, the 5' ends are not unique, and we argue that this variation existed at the time each element transposed. We also provide evidence that CR1 elements transposed into preferred target sites. CR1 elements therefore appear to represent a novel class of passive retroposons.
authors: Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111.
authors: R
authors: R
authors: Silva
authors: J B
authors: JB
authors: Burch
mesh_terms: D000818:Animals; D001483:Base Sequence; D002645:Chickens / Q000235:genetics*; D004251:DNA Transposable Elements; D007438:Introns; D008969:Molecular Sequence Data; D012194:RNA-Directed DNA Polymerase; D012091:Repetitive Sequences, Nucleic Acid; D012689:Sequence Homology, Nucleic Acid; D014819:Vitellogenins / Q000235:genetics
chemical_list: D004251:DNA Transposable Elements; D014819:Vitellogenins; D012194:RNA-Directed DNA Polymerase