title: Exon-intron-like pattern of the first propagating molecule?
abstract: A biogeochemical scenario is proposed, according to which prebiotic self-replication of RNA-like molecules evolved gradually from domain propagation to entire strand replication. The hypothetical replicating entities that formed an evolutionary continuity in time, the prebioectons, were characterized by self-structuring, and started their evolution from strands possessing one or more templatable domains. The inherent self-structuring implies a very early coevolution of the replicating molecules with prebiotic peptides, in line with the cassette model of Cedergren and Grosjean (1987). The proposed approach can be partially tested in the laboratory.
authors: Hebrew University of Jerusalem, Seagram Center for Soil and Water Sciences, Faculty of Agriculture, Rehovot, Israel.
authors: N
authors: N
authors: Lahav
mesh_terms: D005075:Biological Evolution; D004777:Environment; D005091:Exons; D007438:Introns; D009690:Nucleic Acid Conformation; D012313:RNA / Q000096:biosynthesis*; D014158:Transcription, Genetic
chemical_list: D012313:RNA