title: A salivary gland-specific, maltase-like gene of the vector mosquito, Aedes aegypti.
abstract: Genomic and cDNA clones of a gene expressed specifically in the salivary glands of adult Aedes aegypti have been isolated and sequenced. This gene encodes an abundant mRNA that is transcribed throughout the male salivary gland but only in the cells of the proximal lateral lobes of the female gland. The deduced protein has many basic amino acids, several possible sites for N-glycosylation, and displays striking similarities with the products of a yeast maltase gene and three previously unidentified genes from Drosophila melanogaster. We propose the name 'Maltase-like I' (MalI) to designate this gene. The presumed function of this gene product is to assist the mosquito in its sugar-feeding capabilities. The mosquito and fruitfly genes have similar structural features 5' to the protein coding regions, indicating that these genes may share common control mechanisms.
authors: Department of Tropical Public Health, Harvard School of Public Health, Boston, MA 02115.
authors: A A
authors: AA
authors: James
authors: K
authors: K
authors: Blackmer
authors: J V
authors: JV
authors: Racioppi
mesh_terms: D000330:Aedes / Q000235:genetics*; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015152:Blotting, Northern; D003001:Cloning, Molecular; D004247:DNA / Q000302:isolation & purification; D008969:Molecular Sequence Data; D012313:RNA / Q000302:isolation & purification; D012469:Salivary Glands / Q000201:enzymology*; D014158:Transcription, Genetic; D000520:alpha-Glucosidases / Q000235:genetics*
chemical_list: D012313:RNA; D004247:DNA; D000520:alpha-Glucosidases