[An alpha-fetoprotein producing Sertoli-Leydig cell tumor--a case report].
A case of an ovarian, poorly differentiated, Sertoli-Leydig cell tumor in a 55-year-old woman is reported. The patient showed no virilization, but did show elevated serum alpha-fetoprotein (AFP) levels. The tumor, measuring 70 x 45 x 50 mm, consisted mainly of a diffuse proliferation of spindle cells. Among this proliferation, some tubules of Sertoli cells and groups of leydig cells were found. Immunoperoxidase studies, using anti-AFP, localized the AFP in the leydig cells.
Taniyama
K
K
Dept. of Pathology, Shizuoka General Hospital.
Suzuki
H
H
Hara
T
T
Yokoyama
S
S
Tahara
E
E
D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007984:Leydig Cell Tumor / Q000378:metabolism / Q000473:pathology*; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000378:metabolism / Q000473:pathology*; D012707:Sertoli Cell Tumor / Q000378:metabolism / Q000473:pathology*; D000509:alpha-Fetoproteins / Q000378:metabolism*
D000509:alpha-Fetoproteins