AIDS encephalopathy with response to treatment.
A 3 year old boy who had acquired HIV infection transplacentally developed the classical features of AIDS encephalopathy, spastic diplegia and expressive aphasia. His computed tomogram showed cerebral atrophy. Treatment with zidovudine and weekly infusions of gammaglobulin led to considerable clinical improvement and an almost normal computed tomogram nine weeks later.
Matthes
J
J
Department of Paediatrics, Newcastle General Hospital.
Walker
L A
LA
Watson
J G
JG
Bird
A G
AG
D000998:Antiviral Agents / Q000627:therapeutic use; D001927:Brain Diseases / Q000150:complications / Q000628:therapy*; D002675:Child, Preschool; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D008297:Male; D009894:Opportunistic Infections / Q000209:etiology; D013936:Thymidine / Q000031:analogs & derivatives / Q000627:therapeutic use; D015215:Zidovudine; D005719:gamma-Globulins / Q000627:therapeutic use
D000998:Antiviral Agents; D005719:gamma-Globulins; D015215:Zidovudine; D013936:Thymidine