title: [Antibody adsorption to tetrodotoxin-sensitive cytoplasmic proteins by murine neuroblastoma cells].
abstract: The study was aimed to examine properties of polyclonal antibodies elicited after immunization by cytoplasmic nerve cell glycoproteins forming sodium channels in liposomes. It was shown that intact murine neuroblastoma cells can absorb these antibodies. Absorbing cell dose-effect curves were found to have a characteristic form able to shift when the cell culture time or serum concentration in the growth medium varied.
authors: G V
authors: GV
authors: Pinchuk
authors: L N
authors: LN
authors: Pinchuk
authors: O V
authors: OV
authors: Gerasimenko
mesh_terms: D000327:Adsorption; D000818:Animals; D000912:Antibodies, Neoplasm / Q000502:physiology*; D004306:Dose-Response Relationship, Immunologic; D000939:Epitopes; D006023:Glycoproteins / Q000276:immunology / Q000378:metabolism*; D007114:Immunization; D007473:Ion Channels / Q000378:metabolism; D008081:Liposomes / Q000378:metabolism; D051379:Mice; D024101:Mitochondrial Proteins; D009363:Neoplasm Proteins / Q000276:immunology / Q000378:metabolism*; D009447:Neuroblastoma / Q000276:immunology / Q000378:metabolism*; D011485:Protein Binding; D012964:Sodium / Q000378:metabolism; D013779:Tetrodotoxin; D014407:Tumor Cells, Cultured
chemical_list: D000912:Antibodies, Neoplasm; D000939:Epitopes; D006023:Glycoproteins; D007473:Ion Channels; D008081:Liposomes; D024101:Mitochondrial Proteins; D009363:Neoplasm Proteins; C031044:insulin-dependent cytoplasmic regulator protein, rat; D013779:Tetrodotoxin; D012964:Sodium
vernacular_title: Adsorbtsiia antitel k tsitoplazmaticheskim tetrodotoksinchuvstvitel'nym belkam kletkami myshinoĭ neĭroblastomy.