title: Secondary structure prediction for RNA binding domain in RNP proteins identifies beta alpha beta as the main structural motif.
abstract: In eukaryotic cells transcript processing is strictly dependent upon binding of specific proteins. Nuclear RNA binding proteins share a common domain, which is involved in RNA binding. In order to characterize RNP-RNA interactions we have performed a secondary structure prediction based both on statistical algorithms and comparative analysis of different proteins. A high conservation for secondary structure propensity between different RNPs was observed.
authors: Istituto di Scienze Biologiche, Università di Verona, Italy.
authors: A
authors: A
authors: Ghetti
authors: C
authors: C
authors: Padovani
authors: G
authors: G
authors: Di Cesare
authors: C
authors: C
authors: Morandi
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D003198:Computer Simulation; D006801:Humans; D006860:Hydrogen Bonding; D008969:Molecular Sequence Data; D011487:Protein Conformation; D012313:RNA / Q000378:metabolism; D012261:Ribonucleoproteins / Q000648:ultrastructure
chemical_list: D012261:Ribonucleoproteins; D012313:RNA