Pseudomelanosis of the duodenum. Endoscopic, histologic, and ultrastructural study of a case.
We present the endoscopic, microscopic, and histochemical studies of a patient with pseudomelanosis of the duodenum. The pigment was located mainly in the lysosomes of macrophages in the lamina propria and was heterogeneous, showing features of melanin, pseudomelanin, and hemosiderin. The origin of this pigment remains unknown, but antihypertensive medication may have played a role.
Castellano
G
G
Service of Gastroenterology, Hospital 1 de Octubre, Universidad Complutense, Madrid, Spain.
Canga
F
F
Lopez
I
I
Colina
F
F
Gutierrez
J
J
Costa
R
R
Solis-Herruzo
J A
JA
D000368:Aged; D004378:Duodenal Diseases / Q000473:pathology*; D004384:Duodenoscopy; D004386:Duodenum / Q000032:analysis* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000032:analysis; D008247:Lysosomes / Q000032:analysis; D008264:Macrophages / Q000032:analysis / Q000648:ultrastructure; D008548:Melanosis / Q000473:pathology*; D008854:Microscopy, Electron; D010860:Pigments, Biological / Q000032:analysis; D012737:Sex Factors; D013194:Staining and Labeling
D010860:Pigments, Biological