[Interferon-induced effects of lectins in vitro and following oral administration].
The interferon inducing effects of lectins such as ConA, PHA, LCA und WGA had been demonstrated. The studies were carried out in human-blood-cell cultures and in serum of mice after an oral uptake of substances subjected. In both experiments under determined conditions the lectins showed an interferogen effect. Especially efficacious was WGA. Most interesting was the systemic IFN-activation after oral stimulation using WGA.
Schubert
K
K
Forschungsinstitut für Lungenkrankheiten und Tuberkulose Berlin-Buch/DDR.
Noack
K
K
Luther
P
P
D000284:Administration, Oral; D000818:Animals; D002460:Cell Line; D003588:Cytopathogenic Effect, Viral / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D007369:Interferon Inducers; D007372:Interferons / Q000096:biosynthesis*; D037102:Lectins / Q000008:administration & dosage*; D051379:Mice; D014407:Tumor Cells, Cultured / Q000187:drug effects
D007369:Interferon Inducers; D037102:Lectins; D007372:Interferons
Interferoninduzierende Effekte von Lektinen in vitro und nach oraler Applikation.