title: In vivo functional localization of the human visual cortex using positron emission tomography and magnetic resonance imaging.
abstract: Positron emission tomography (PET) and magnetic resonance imaging (MRI) are two recently developed methods for imaging the human brain in vivo. One application of PET measures stimulus-evoked changes in cerebral blood flow while MRI provides a detailed anatomical map of the brain. Here we report the combined application of these two techniques in the same human subject. Subtracted PET scans of a brain receiving visual stimulation were superimposed upon MRI images of the same brain. The PET scans were converted into the MRI coordinate space before superposition, which allowed for a more precise correlation between MRI anatomical data and PET physiological data. Responses were localized in striate and extrastriate visual areas as well as in the posterior thalamus.
authors: B N
authors: BN
authors: Mora
authors: G J
authors: GJ
authors: Carman
authors: J M
authors: JM
authors: Allman
mesh_terms: D006801:Humans; D008279:Magnetic Resonance Imaging; D014055:Tomography, Emission-Computed; D014793:Visual Cortex / Q000502:physiology*