Substance P-like immunoreactivity in the gracile nucleus and fasciculus in old mice.
Substance P-like immunoreactivity (SPI) was observed in many axonal profiles within the gracile nucleus and fasciculus of 13-month-old mice. No SPI, however, was detected in the gracile nucleus and fasciculus in 3- and 6-month-old mice. The results suggest that the accumulation of SPI elements in axons of the gracile nucleus and fasciculus is one of the age-related changes in the central nervous system.
Yamazaki
K
K
National Institute of Neuroscience, NCNP, Tokyo, Japan.
Moriya
H
H
Wakabayashi
T
T
Kikuchi
T
T
D000818:Animals; D007150:Immunohistochemistry; D008297:Male; D008526:Medulla Oblongata / Q000166:cytology / Q000378:metabolism*; D051379:Mice; D008807:Mice, Inbred BALB C; D013116:Spinal Cord / Q000166:cytology / Q000378:metabolism*; D013373:Substance P / Q000378:metabolism*
D013373:Substance P