title: Catalysis by the RNA subunit of RNase P--a minireview.
abstract: RNase P, an enzyme that contains both RNA and protein components, cleaves tRNA precursors to generate mature 5' termini. The catalytic activity of RNase P resides in the RNA component, with the protein cofactor affecting the rate of the cleavage reaction. The reaction is also influenced by the nature of the tRNA substrate.
authors: Department of Biology, Yale University, New Haven, CT 06520.
authors: S
authors: S
authors: Altman
authors: M F
authors: MF
authors: Baer
authors: M
authors: M
authors: Bartkiewicz
authors: H
authors: H
authors: Gold
authors: C
authors: C
authors: Guerrier-Takada
authors: L A
authors: LA
authors: Kirsebom
authors: N
authors: N
authors: Lumelsky
authors: K
authors: K
authors: Peck
mesh_terms: D002384:Catalysis; D004722:Endoribonucleases / Q000502:physiology*; D009690:Nucleic Acid Conformation; D012313:RNA / Q000502:physiology*; D012322:RNA Precursors / Q000378:metabolism*; D012326:RNA Splicing; D012338:RNA, Ribosomal, 23S / Q000378:metabolism; D043262:Ribonuclease P; D013379:Substrate Specificity
chemical_list: D012322:RNA Precursors; D012338:RNA, Ribosomal, 23S; D012313:RNA; D004722:Endoribonucleases; D043262:Ribonuclease P