title: Juxtapapillary choroidal neovascular membrane in a patient with Paget's disease and lattice corneal dystrophy.
abstract: Paget's disease (osteitis deformans) is a relatively common metabolic bone disease characterized by the gradual development of bony deformities. These deformities lead to cranial and peripheral neuropathies from nerve and blood vessel impingement. Angioid streaks are associated with Paget's disease and are the result of linear breaks in Bruch's membrane caused by the calcification and degeneration of this elastic tissue layer. A case report of a patient with Paget's disease with angioid streaks and a secondary choroidal neovascular membrane is presented. The membrane was treated with argon laser photocoagulation. The patient also had an incidental finding of lattice corneal dystrophy which required penetrating keratoplasty.
authors: Eye Clinic, Veterans Administration Medical Center, Baltimore/Fort Howard, MD 21052.
authors: J D
authors: JD
authors: Boehme
authors: A B
authors: AB
authors: Litwak
mesh_terms: D000368:Aged; D000793:Angioid Streaks / Q000150:complications; D002387:Cataract Extraction; D002829:Choroid / Q000098:blood supply*; D003317:Corneal Dystrophies, Hereditary / Q000150:complications*; D016039:Corneal Transplantation; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy; D008028:Light Coagulation; D008297:Male; D009389:Neovascularization, Pathologic / Q000175:diagnosis*; D010001:Osteitis Deformans / Q000150:complications* / Q000000981:diagnostic imaging; D011859:Radiography; D014792:Visual Acuity