Studies on monoamine levels in rat myocardium in different stresses.
Albino rats were exposed to isolation, haemorrhagic, and psychic stress. The myocardial norepinephrine (NE), epinephrine (E), dopamine (DA), 5-hydroxytryptamine (5HT) and 5-hydroxy indole acetic acid (5HIAA) were quantitatively estimated at varying periods of time. The results indicate that 5HT, E, and DA are the common denominators in various types of stress and show similar qualitative changes in all the stresses studied whereas norepinephrine shows both quantitative and qualitative differences in the various stresses studied indicating thereby a differential modulatory mechanisms operating for the release of noradrenaline.
Suthanthirarajan
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N
Department of Physiology, P.G. Institute of Basic Medical Sciences, University of Madras, Taramani.
Namasivayam
A
A
D000818:Animals; D001679:Biogenic Amines / Q000378:metabolism*; D004298:Dopamine / Q000378:metabolism; D004837:Epinephrine / Q000378:metabolism; D006470:Hemorrhage / Q000378:metabolism; D006897:Hydroxyindoleacetic Acid / Q000378:metabolism; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000378:metabolism; D012934:Social Isolation; D013312:Stress, Physiological / Q000378:metabolism*; D013315:Stress, Psychological / Q000378:metabolism
D001679:Biogenic Amines; D012701:Serotonin; D006897:Hydroxyindoleacetic Acid; D004298:Dopamine; D009638:Norepinephrine; D004837:Epinephrine