Hemostasis of solid viscus trauma by intraparenchymal injection of fibrin glue.
Fibrin glue (FG) is an effective hemostatic agent applied topically to the spleen. In this study, FG was found to be an effective hemostatic agent when applied topically in standardized wounds of the canine liver, spleen, and pancreas. It was markedly more effective, however, when injected intraparenchymally. In a case of severe blunt trauma in a patient with acute alcoholic hepatitis, intraparenchymal FG was lifesaving. Fibrin glue is a useful adjunct in the management of trauma to all the abdominal solid viscera. Intraparenchymal injection is the preferred mode of FG application.
Hauser
C J
CJ
Division of Trauma, Hollywood Presbyterian Medical Center, Los Angeles CA 90027.
D000287:Administration, Topical; D000328:Adult; D000818:Animals; D007611:Aprotinin / Q000008:administration & dosage*; D004285:Dogs; D004338:Drug Combinations / Q000008:administration & dosage; D005176:Factor XIII / Q000008:administration & dosage*; D005337:Fibrin / Q000008:administration & dosage*; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen / Q000008:administration & dosage*; D006488:Hemostasis, Surgical / Q000379:methods*; D006801:Humans; D007267:Injections; D008099:Liver / Q000293:injuries*; D008297:Male; D010179:Pancreas / Q000293:injuries*; D013154:Spleen / Q000293:injuries*; D013917:Thrombin / Q000008:administration & dosage*; D014014:Tissue Adhesives / Q000008:administration & dosage*; D014950:Wounds, Penetrating / Q000601:surgery*
D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives; D005337:Fibrin; D005340:Fibrinogen; D005176:Factor XIII; D007611:Aprotinin; D013917:Thrombin