[Opsonic and anti-opsonic effects of the synovial fluid in patients with rheumatoid arthritis based on its effect on the complement-dependent adhesion of neutrophils].
A method has been developed for the assessment of the synovial fluid (SF) complement-dependent opsonic characteristics basing on the intensity of neutrophil adhesion to SF-pretreated Sephadex granules. Examinations of 25 patients with rheumatoid arthritis have detected the lowest complement-dependent opsonization (CDD) in the patients with extraarticular symptoms. CDD showed a tendency to normalization over the course of intraarticular glucocorticoid therapy. No anti-opsonic effects of SF have been recorded. Examinations of 8 synovial exudates from patients with osteoarthrosis deformans have revealed SF CDD much higher than that in rheumatoid arthritis patients.
Salikhov
I G
IG
Fomina
L L
LL
Maianskiĭ
A N
AN
Konyshkina
T M
TM
D001172:Arthritis, Rheumatoid / Q000276:immunology*; D002448:Cell Adhesion; D003165:Complement System Proteins / Q000276:immunology*; D006801:Humans; D066298:In Vitro Techniques; D009504:Neutrophils / Q000276:immunology*; D009895:Opsonin Proteins / Q000276:immunology*; D013582:Synovial Fluid / Q000276:immunology*
D009895:Opsonin Proteins; D003165:Complement System Proteins
Issledovanie opsonicheskikh i antiopsonicheskikh éffektov sinovial'noĭ zhidkosti bol'nykh revmatoidnym artritom po vliianiiu na komplementzavisimuiu adgeziiu neĭtrofilov,