Ontogenesis of endocrine cells in the chicken intestine: an immunohistochemical study.
The authors report the time of appearance, morphology and topographic distribution of gastrin/cholecystochinin- (G/CCK-), somatostatin- (SRIF-), neurotensin- (NT-), motilin- (MO-) and substance P-like immunoreactive (SP-LI) elements during embryonic and postnatal development, in ileum, caeca and colon of chick embryos (from 8 days of incubation to hatching), newborn chicks (up to 15-days old) and adult chickens. In the ileum, G/CCK-LI and SP-LI cells appeared on day 11, the others on about day 13. In the caeca the first cells of all types were seen from about day 17. In the colon, NT-LI cells appeared early, on day 9, SP-LI and occasional SRIF-LI cells from day 13 on and MO-LI and G/CCK-LI only from day 17. In the ileum all the cells studied were present, in the caeca and colon they were extremely scarce, apart from NT-LI cells which were more numerous. In the prenatal stages, SP-LI was found only in epithelial cells; after hatching, it was also present in metasympathetic nerve elements.
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D000375:Aging; D000818:Animals; D002432:Cecum / Q000166:cytology / Q000196:embryology / Q000254:growth & development*; D002642:Chick Embryo; D002645:Chickens; D002766:Cholecystokinin / Q000032:analysis; D003106:Colon / Q000166:cytology / Q000196:embryology / Q000254:growth & development*; D005755:Gastrins / Q000032:analysis; D007082:Ileum / Q000166:cytology / Q000196:embryology / Q000254:growth & development*; D009037:Motilin / Q000032:analysis; D009479:Neuropeptides / Q000032:analysis*; D009496:Neurotensin / Q000032:analysis; D013004:Somatostatin / Q000032:analysis; D013373:Substance P / Q000032:analysis
D005755:Gastrins; D009479:Neuropeptides; D013373:Substance P; D009496:Neurotensin; D013004:Somatostatin; D009037:Motilin; D002766:Cholecystokinin