[Study of transcription of the DNA sequence of a mts271 clone in various tumor and normal mouse cells].
Transcription of the mts271 gene was studied in 27 mouse cell tumor lines. Transcripts of the gene have been found in 6 out of 7 different metastatic lines. No transcription of the gene has been observed in non-metastatic tumor lines. In normal tissues, specific gene DNA was only found in hemopoietic cells--in bone marrow, spleen, thymus and lymphocytes. Transcription of the gene mts271 is not dependent on the level of DNA methylation.
Grigorian
M S
MS
Ebralidze
A K
AK
Tyl'chinskiĭ
E M
EM
Revazova
E S
ES
Senin
V M
VM
Lukanidin
E M
EM
D000818:Animals; D002478:Cells, Cultured; D002999:Clone Cells; D004247:DNA / Q000235:genetics* / Q000302:isolation & purification; D004273:DNA, Neoplasm / Q000235:genetics* / Q000302:isolation & purification; D015870:Gene Expression; D008745:Methylation; D051379:Mice; D009362:Neoplasm Metastasis; D009693:Nucleic Acid Hybridization; D012313:RNA / Q000235:genetics / Q000302:isolation & purification; D012334:RNA, Neoplasm / Q000235:genetics / Q000302:isolation & purification; D014158:Transcription, Genetic; D014407:Tumor Cells, Cultured
D004273:DNA, Neoplasm; D012334:RNA, Neoplasm; D012313:RNA; D004247:DNA
Issledovanie transcriptsii posledovatelnosteĭ DNK klona mts271 v razlichnykh opukholevykh i normal'nykh kletkakh myshi.