Postinflammatory hyperpigmentation.
The epidermis provides a barrier against environmental toxins. The epidermal inflammatory response (dermatitis) causes the release of many peptides, chemical agents that alter the activity of both immune cells and pigment cells. Postinflammatory pigmentation may be an indicator that the melanocytes are part of the epidermal inflammatory system. Programs for treatment of postinflammatory pigmentation have been outlined.
Nordlund
J J
JJ
Department of Dermatology, University of Cincinnati College of Medicine, Ohio.
D000818:Animals; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000502:physiology; D003872:Dermatitis / Q000503:physiopathology*; D006801:Humans; D006854:Hydrocortisone / Q000502:physiology; D007372:Interferons / Q000502:physiology; D007375:Interleukin-1 / Q000502:physiology; D009074:Melanocyte-Stimulating Hormones / Q000502:physiology; D008544:Melanocytes / Q000502:physiology; D010859:Pigmentation Disorders / Q000628:therapy; D011453:Prostaglandins / Q000502:physiology; D012880:Skin Pigmentation; D014807:Vitamin D / Q000502:physiology
D001095:Arachidonic Acids; D007375:Interleukin-1; D011453:Prostaglandins; D014807:Vitamin D; D016718:Arachidonic Acid; D009074:Melanocyte-Stimulating Hormones; D007372:Interferons; D006854:Hydrocortisone