title: Pacing failure due to markedly increased stimulation threshold 2 years after implantation: successful management with oral prednisolone: a case report.
abstract: In a 53-year-old male who had undergone transvenous permanent pacing, intracardiac potential reduced progressively over a 2-year period and exit block developed, while the stimulation threshold was markedly increased. After oral prednisolone for 5 months, the stimulation threshold reduced gradually along with an increase in intracardiac potential, culminating in no recurrence of exit block for the ensuing 2 years. The clinical course suggests that progressive reduction in intracardiac potential may have presaged the late development of exit block, and that oral prednisolone may be a therapeutic approach for the restoration of ventricular capture even 2 years after implantation.
authors: First Department of Internal Medicine, Miyazaki Medical College, Japan.
authors: Y
authors: Y
authors: Nagatomo
authors: T
authors: T
authors: Ogawa
authors: H
authors: H
authors: Kumagae
authors: Y
authors: Y
authors: Koiwaya
authors: K
authors: K
authors: Tanaka
mesh_terms: D000284:Administration, Oral; D002304:Cardiac Pacing, Artificial / Q000009:adverse effects*; D004868:Equipment Failure; D006327:Heart Block / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D011239:Prednisolone