title: Adult follow-up of the acquired aphasia-epilepsy syndrome in childhood. Report of 7 cases.
abstract: The authors report at adult age 7 patients (6 men, one woman) with the syndrome of "acquired aphasia-epilepsy", 6 of which had been previously studied as children. The results of the language, neuropsychological and socio-educational evaluation detailed many years after the onset of the aphasia are the subject of this report. One man has recovered completely, one has a normal oral language but is severely dyslexic, one has recovered normal comprehension but has severe expressive language problems. Four have absent language comprehension and lack of expressive speech, and only one of them has learned and is using sign language with some efficiency. None has developed functional written language. Attempts to offer a substitutive language to children with prolonged inability to understand and use oral language appears important but is fraught with problems. Although there are no conclusive data about the role of the continuous paroxysmal EEG discharges and the effect of their suppression with drug treatment on the prognosis of the aphasia, the definite fluctuations of the aphasia in some cases, the isolated recent case reports of definitive improvement with drug treatment justify further trials in this potentially severe and chronic condition.
authors: Pediatric Department, CHUV, Lausanne, Switzerland.
authors: T
authors: T
authors: Deonna
authors: C
authors: C
authors: Peter
authors: A L
authors: AL
authors: Ziegler
mesh_terms: D000293:Adolescent; D000328:Adult; D001037:Aphasia / Q000150:complications / Q000503:physiopathology*; D004827:Epilepsy / Q000150:complications / Q000503:physiopathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007806:Language Disorders / Q000209:etiology*; D008297:Male; D013577:Syndrome