title: Dermal toxicity of hexachlorocyclohexane (HCH) in rabbit.
abstract: Application of HCH (25 mg/kg) on dorsal, ventral and thigh regions of the skin of male rabbits resulted in poisoning and mortality of animals. Morphological changes in skin, liver, kidney, testes and cerebellum together with highly significant alterations in serum and liver enzymatic activity and residue in blood suggested that absorption of HCH and its toxicity could be severe when the pesticide comes in contact with the skin of thigh region of body.
authors: T S
authors: TS
authors: Dikshith
authors: R B
authors: RB
authors: Raizada
authors: M K
authors: MK
authors: Srivastava
authors: S N
authors: SN
authors: Kumar
authors: R A
authors: RA
authors: Kaushal
authors: R P
authors: RP
authors: Singh
authors: K P
authors: KP
authors: Gupta
authors: K S
authors: KS
authors: Lakshmi
mesh_terms: D000818:Animals; D002531:Cerebellum / Q000187:drug effects; D001556:Hexachlorocyclohexane / Q000493:pharmacokinetics / Q000633:toxicity*; D007668:Kidney / Q000187:drug effects; D008099:Liver / Q000187:drug effects; D008297:Male; D011817:Rabbits; D012867:Skin / Q000187:drug effects*; D012869:Skin Absorption; D013737:Testis / Q000187:drug effects
chemical_list: D001556:Hexachlorocyclohexane