[Results of pregnancies characterized by a decrease in the level of alpha-fetoprotein in the maternal blood].
Pregnancy outcome was followed in 123 women showing maternal serum alpha-fetoprotein, less than or equal to 0.50 MOM. In 28 cases AFP was secondarily considered as normal either after ultrasonography and correction of gestation age or after a second sample normal result. In 95 cases AFP level was confirmed lowered; perinatal outcome was normal in 70 cases and abnormal in 25. Among these 25 cases, 3 autosomal trisomies occurred, 2 trisomies 18 and 1 trisomy 21; in the 22 other cases, we observed antepartum risk factors (10 cases with impending premature labor or premature labor, 9 cases with chronic hypertension, 2 cases with Ag HBs hepatitis and 1 case with diabetes).
Guibaud
S
S
Laboratoire Central, Hôpital de la Croix-Rousse, Lyon.
Boisson
C
C
Simplot
A
A
Thoulon
J M
JM
Guibaud
P
P
Robert
J M
JM
D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood* / Q000175:diagnosis; D014314:Trisomy; D014463:Ultrasonography; D000509:alpha-Fetoproteins / Q000172:deficiency*
D000509:alpha-Fetoproteins
Suivi de grossesses caractérisées par une diminution du taux d'alpha-foetoprotéine dans le sang maternel.