title: DNA----DNA, and DNA----RNA----protein: orchestration by a single complex operon.
abstract: In Escherichia coli, the workhorse of molecular biology, a single operon is involved in the replication, transcription and translation of genetic information. This operon is controlled in a complex manner involving multiple cis-acting regulatory sequences and trans-acting regulatory proteins. It interacts with global regulatory networks by mechanisms which are presently being dissected.
authors: J R
authors: JR
authors: Lupski
authors: G N
authors: GN
authors: Godson
mesh_terms: D000595:Amino Acid Sequence; D001412:Bacillus subtilis / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics*; D019915:DNA Primase; D004261:DNA Replication; D004269:DNA, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics*; D005796:Genes; D005798:Genes, Bacterial; D008969:Molecular Sequence Data; D014176:Protein Biosynthesis; D012316:RNA Nucleotidyltransferases / Q000235:genetics; D012329:RNA, Bacterial / Q000235:genetics*; D012486:Salmonella typhimurium / Q000235:genetics; D012689:Sequence Homology, Nucleic Acid; D014158:Transcription, Genetic
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; D012329:RNA, Bacterial; D019915:DNA Primase; D012316:RNA Nucleotidyltransferases