title: Prefabricated neovascularized free muscle flaps: pedicle variations.
abstract: Current techniques of free muscle transplantation with microvascular anastomosis have the disadvantages of limitation of available donor sites, loss of donor muscle function, and the possibility of donor site defect or deformity. Using modifications of a "secondary tissue flap" created by neovascularization of a given tissue, neovascularized muscle flaps with pedicle vessels were created by wrapping external abdominal oblique muscles around the superficial inferior epigastric blood vessels. Different pedicle types were examined to explore possible differences in neovascularization. In 60 rats, four groups of neovascularized muscle flaps were created and transplanted as free flaps, with a high degree of success. After transplantation, neovascularization of the flaps was evaluated by histology and latex casts of vascular tree of the muscle flaps. Degree of neovascularization differed, depending on the type of vascular pedicle used to create the flap.
authors: Department of Plastic Surgery, NYU/Bellevue Medical Center, New York.
authors: F A
authors: FA
authors: Valauri
authors: Y
authors: Y
authors: Hirasé
authors: H J
authors: HJ
authors: Buncke
mesh_terms: D000009:Abdominal Muscles / Q000098:blood supply*; D000818:Animals; D001158:Arteries / Q000601:surgery; D001166:Arteriovenous Shunt, Surgical; D005263:Femoral Artery / Q000601:surgery; D005268:Femoral Vein / Q000601:surgery; D008297:Male; D009132:Muscles / Q000098:blood supply / Q000473:pathology / Q000637:transplantation*; D009133:Muscular Atrophy / Q000473:pathology; D009389:Neovascularization, Pathologic / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains; D013524:Surgical Flaps; D014654:Vascular Patency; D014680:Veins / Q000601:surgery