Demonstration of tenascin-like immunoreactivity in rabbit corneal wounds.
Tenascin, a novel extracellular matrix protein, was demonstrated immunohistochemically in rabbit corneas that had healed after anterior keratectomy. Tenascin-like immunofluorescence (T-LI) appeared in the corneal stroma at the wound area only. The wound edge showed the most intense specific fluorescence. The corneal epithelium, in general, displayed a moderate T-LI. Wounding did not induce any change in epithelial T-LI or T-LI located in the stroma outside the wound.
Tervo
K
K
Department of Anatomy, University of Helsinki, Finland.
Tervo
T
T
van Setten
G B
GB
Tarkkanen
A
A
Virtanen
I
I
D000818:Animals; D003315:Cornea / Q000378:metabolism / Q000601:surgery*; D005260:Female; D007150:Immunohistochemistry; D008297:Male; D011506:Proteins / Q000378:metabolism*; D011817:Rabbits; D019063:Tenascin
D011506:Proteins; D019063:Tenascin