[Progesterone-induced activation of RNA-binding casein kinase type II during maturation of frog oocytes].
During progesterone-induced maturation of the Rana temporaria oocytes phosphorylation of RNA(heparin)-binding proteins changes drastically due to the alterations in the activity of RNA-binding casein kinase II. Its activity increases 7 hr later administration of progesterone and correlates with the level of translation in oocytes. Cycloheximide almost completely inhibits the protein biosynthesis but has no effect on the activity of RNA-binding casein kinase and the set of phosphorylated polypeptides. The possibility is discussed that this enzyme participates in the translation control mechanisms.
Stepanov
A S
AS
Kandror
K V
KV
D000818:Animals; D047388:Casein Kinases; D004789:Enzyme Activation; D009865:Oocytes / Q000201:enzymology / Q000254:growth & development*; D010766:Phosphorylation; D011374:Progesterone / Q000494:pharmacology*; D011494:Protein Kinases / Q000378:metabolism*; D012313:RNA / Q000378:metabolism*; D011896:Rana temporaria
D011374:Progesterone; D012313:RNA; D011494:Protein Kinases; D047388:Casein Kinases
Indutsiruemaia progesteronom aktivatsiia RNK-sviazyvaiushcheĭ kazeinovoĭ kinazy tipa II pri sozrevanii ootsitov liagushki.