[Use of antilymphocytic gamma globulin to monitor the course of viral hepatitis B].
The authors suggest a method for immunologic monitoring of the lymphocytic activity in viral hepatitis B (VHB) by the antilymphocytic gammaglobulin (ALG) capacity to inhibit rosette formation with sheep red blood cells. The findings evidence that sensitivity to ALG augments in the majority of VHB patients, this manifesting as an increased titre of this globulin inhibiting activity in the E-rosette formation test. A decreased sensitivity of the lymphocytes to the effects of specific antibodies points to activation of T lymphocytes and is regarded as an unfavourable prognostic sign.
Gerasun
B A
BA
Burlev
V A
VA
Danileĭchenko
I V
IV
D000328:Adult; D005260:Female; D006509:Hepatitis B / Q000276:immunology*; D006801:Humans; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D012397:Rosette Formation; D005719:gamma-Globulins / Q000032:analysis*
D005719:gamma-Globulins
Ispol'zovanie antilimfotsitarnogo gamma-globulina dlia kontrolia techeniia virusnogo gepatita B.