Studies of peptidergic input to the lateral spinal nucleus.
Lesions were made to interrupt potential sources of peptidergic input to the lateral spinal nucleus (LSn) in rats. Rhizotomies and spinal transections, as well as lesions of the lateral funiculus, failed to reduce immunohistochemical staining for substance P, dynorphin, Met-enkephalin, somatostatin and FMRF-amide in the LSn at lumbar levels. Thus, all examined peptidergic afferent input to the LSn appears to originate locally within the spinal cord.
Cliffer
K D
KD
Department of Cell Biology and Neuroanatomy, University of Minnesota, Minneapolis 55455.
Urca
G
G
Elde
R P
RP
Giesler
G J
GJ
D000818:Animals; D004399:Dynorphins / Q000032:analysis* / Q000276:immunology; D004744:Enkephalin, Methionine / Q000032:analysis* / Q000276:immunology; D019835:FMRFamide; D005455:Fluorescent Antibody Technique; D007106:Immune Sera; D007796:Laminectomy; D008297:Male; D009479:Neuropeptides / Q000032:analysis* / Q000276:immunology; D010446:Peptide Fragments / Q000032:analysis* / Q000276:immunology; D051381:Rats; D011919:Rats, Inbred Strains; D013004:Somatostatin / Q000032:analysis* / Q000276:immunology; D013116:Spinal Cord / Q000166:cytology / Q000502:physiology*; D013373:Substance P / Q000032:analysis / Q000276:immunology
D007106:Immune Sera; D009479:Neuropeptides; D010446:Peptide Fragments; D013373:Substance P; D013004:Somatostatin; D004744:Enkephalin, Methionine; D019835:FMRFamide; D004399:Dynorphins; C026770:dynorphin (1-8)