title: Dose-response analysis of infants prenatally exposed to methyl mercury: an application of a single compartment model to single-strand hair analysis.
abstract: A new method of estimating fetal exposure is used in a dose-response analysis of data from the 1971 outbreak of methyl mercury poisoning in rural Iraq. An X-ray fluorescence instrument for the measurement of single strands of human hair was employed to obtain longitudinal profiles recapitulating fetal exposure. Logit and hockey-stick models as well as nonparametric smoothing are used to describe data on delayed development and central nervous system abnormality.
authors: Division of Biostatistics, University of Rochester School of Medicine, New York 14642.
authors: C
authors: C
authors: Cox
authors: T W
authors: TW
authors: Clarkson
authors: D O
authors: DO
authors: Marsh
authors: L
authors: L
authors: Amin-Zaki
authors: S
authors: S
authors: Tikriti
authors: G G
authors: GG
authors: Myers
mesh_terms: D001939:Bread; D002490:Central Nervous System / Q000187:drug effects; D002658:Developmental Disabilities / Q000209:etiology; D005260:Female; D005506:Food Contamination; D006197:Hair / Q000032:analysis*; D006801:Humans; D007231:Infant, Newborn; D007493:Iraq; D008431:Maternal-Fetal Exchange; D008767:Methylmercury Compounds / Q000506:poisoning*; D008962:Models, Theoretical; D011247:Pregnancy; D012307:Risk Factors; D013052:Spectrometry, X-Ray Emission / Q000379:methods
chemical_list: D008767:Methylmercury Compounds