title: Accuracy of two wavelength pulse oximetry in neonates and infants.
abstract: In 60 neonates (gestational age, 26.5-40 weeks; postnatal age, 1-14 days) and in 11 infants (gestational age, 26-33 weeks; postnatal age, 4.5-38 weeks), the accuracy of two wavelength pulse oximetry was examined. A total of 112 comparisons between transcutaneous pulse oximetry saturation (StcO2, NELLCOR N-100) and arterial oxygen saturation (SaO2, OSM2 RADIOMETER) were obtained. SaO2 ranged from 80 to 100%. Criteria for comparison between StcO2 and SaO2 were standardized: patients in behavioral state 1, StcO2 stable for 2 min, and arterial samples drawn from an indwelling arterial line. StcO2 was significantly related to SaO2 (P less than 0.01), but the difference, StcO2 - SaO2, significantly increased when SaO2 decreased [StcO2 - SaO2(%) = -0.39 SaO2(%) + 37.95; r = -0.64, P less than 0.01]. No significant relationship was found between StcO2 - SaO2 and either bilirubinemia (range, 5-222 mumol/L) or fetal hemoglobin (HbF) (range, 12-95%). We conclude that StcO2 overestimates SaO2 when SaO2 decreases, and this overestimation is not due to high levels of bilirubin or HbF.
authors: Laboratory of Physiology, CNRS UA 1159, Hospital Antoine Béclère, Clamart, France.
authors: J P
authors: JP
authors: Praud
authors: A
authors: A
authors: Carofilis
authors: F
authors: F
authors: Bridey
authors: F
authors: F
authors: Lacaille
authors: M
authors: M
authors: Dehan
authors: C L
authors: CL
authors: Gaultier
mesh_terms: D001663:Bilirubin / Q000097:blood; D001785:Blood Gas Monitoring, Transcutaneous; D001997:Bronchopulmonary Dysplasia / Q000097:blood*; D005319:Fetal Hemoglobin / Q000032:analysis; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010100:Oxygen / Q000097:blood*; D012120:Respiration Disorders / Q000097:blood*
chemical_list: D005319:Fetal Hemoglobin; D001663:Bilirubin; D010100:Oxygen