The impact of intrauterine transfusions on morphological picture of red cells in Rh incompatibility.
The purpose of the study was to analyse the changing picture of red cells in fetuses treated with intrauterine transfusions for Rh incompatibility. The study included 28 live-born infants who were given 48 intrauterine transfusions. The reference group consisted of 232 newborns with haemolytic disease of the newborn (HDN), untreated in the fetal period. The number of erythroblasts and reticulocytes in the red cells along with fetal haemoglobin (HbF), in relation to the number of the own erythrocytes of the fetus and the total number of red cells in cord blood were examined. The suppressing influence of the transfused blood on haematopoiesis and a significant stimulation of erythrocyte renowal, in cases of smaller number of HbF erythrocytes in cord blood were observed.
Lozińska
D
D
Department of Neonatology, Medical Centre of Postgraduate Education, Warsaw.
D001805:Blood Transfusion, Intrauterine; D004899:Erythroblastosis, Fetal / Q000097:blood / Q000517:prevention & control*; D004900:Erythroblasts / Q000473:pathology; D004906:Erythrocyte Count; D004912:Erythrocytes / Q000473:pathology*; D005260:Female; D005319:Fetal Hemoglobin / Q000032:analysis; D006410:Hematopoiesis; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D012156:Reticulocytes / Q000473:pathology
D005319:Fetal Hemoglobin