[Effect of terrilytin on the activity of nonspecific resistance factors during immunization with staphylococcal anatoxin and staphylococcal infection].
Terrilytin and immobilized terrilytin enhance the activity and intensity of phagocytosis and increase the concentration of lysozyme in nonimmunized animals. Both preparations increase the production of antibodies to staphylococcal alpha-hemolysin, the titers of beta-lysins, the activity and intensity of the phagocytosis of bacterial cells by peripheral blood leukocytes in animals immunized with staphylococcal toxoid and challenged with live staphylococcal culture. In healthy animals terrilytin and immobilized terrilytin induce an increase in total proteolytic activity and in the activity of alpha-1-antitrypsin and alpha-2-macroglobulin, decreased as the result of staphylococcal infection.
Bel'skiĭ
V V
VV
Zakarian
L M
LM
Prokopenko
L G
LG
Chalyĭ
G A
GA
D000681:Amylases / Q000627:therapeutic use*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000907:Antibodies, Bacterial / Q000032:analysis; D004338:Drug Combinations / Q000627:therapeutic use; D004353:Drug Evaluation, Preclinical; D004800:Enzymes, Immobilized / Q000627:therapeutic use*; D007113:Immunity, Innate / Q000187:drug effects; D007114:Immunization; D010447:Peptide Hydrolases / Q000627:therapeutic use*; D010587:Phagocytosis / Q000187:drug effects; D011817:Rabbits; D051381:Rats; D011919:Rats, Inbred Strains; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000276:immunology; D013208:Staphylococcal Toxoid / Q000276:immunology*; D013210:Staphylococcus / Q000276:immunology; D013997:Time Factors
D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D004338:Drug Combinations; D004800:Enzymes, Immobilized; D013208:Staphylococcal Toxoid; C009402:amylase, phosphates, proteases drug combinations; D000681:Amylases; D010447:Peptide Hydrolases
Vliianie terrilitina na aktivnost' faktorov nespetsificheskoĭ rezistentnosti pri immunizatsii stafilokokkovom anatoksinom i infitsirovanii stafilokokkom.