title: [Effect of prazosin on human prostatic adenoma tissue].
abstract: The effect of prazosin on epinephrine-induced contractions of human benign prostatic hyperplasia strips was studied. It was shown that prazosin has a pronounced adrenoblocking activity (EC50 = 5.10(-9) g/ml) but fails to affect strip contractions induced by KCL. It is suggested that prazosin can be used in the treatment of patients suffering from benign prostatic hyperplasia.
authors: M E
authors: ME
authors: Kaminka
authors: M L
authors: ML
authors: Zhirnikova
authors: A Z
authors: AZ
authors: Vinarov
authors: M D
authors: MD
authors: Mashkovskiĭ
authors: Iu A
authors: IuA
authors: Pytel'
mesh_terms: D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D004347:Drug Interactions; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D011224:Prazosin / Q000627:therapeutic use*; D011467:Prostate / Q000187:drug effects; D011470:Prostatic Hyperplasia / Q000188:drug therapy*
chemical_list: D011224:Prazosin
vernacular_title: Vliianie prazozina na tkan' adenomy predstatel'noĭ zhelezy cheloveka.