title: Serum protease inhibitors in opisthorchiasis, hepatoma, cholangiocarcinoma, and other liver diseases.
abstract: Serum alpha 1-antitrypsin, alpha 1-antichymotrypsin and alpha 2-macroglobulin increased significantly in patients suffering from liver diseases: hepatoma, amoebic liver abscess, hepatitis, hepatic cirrhosis, cholangiocarcinoma, carcinoma of the head of pancreas including liver fluke infection (opisthorchiasis). Marked increase of alpha 1-antitrypsin and alpha 1-antichymotrypsin were found in cholangiocarcinoma, carcinoma of the head of pancreas, amoebic liver abscess, hepatic cirrhosis and hepatoma. alpha 2-macroglobulin increased markedly in hepatic cirrhosis. The concentrations of protease inhibitors found in opisthorchiasis were only moderately elevated.
authors: Department of Tropical Nutrition and Food Science, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
authors: S
authors: S
authors: Changbumrung
authors: P
authors: P
authors: Migasena
authors: V
authors: V
authors: Supawan
authors: P
authors: P
authors: Juttijudata
authors: T
authors: T
authors: Buavatana
mesh_terms: D002759:Adenoma, Bile Duct / Q000097:blood; D000328:Adult; D001650:Bile Duct Neoplasms / Q000097:blood; D006528:Carcinoma, Hepatocellular / Q000097:blood; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000097:blood*; D008113:Liver Neoplasms / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009889:Opisthorchiasis / Q000097:blood*; D011480:Protease Inhibitors / Q000097:blood*; D000514:alpha 1-Antichymotrypsin / Q000032:analysis; D000515:alpha 1-Antitrypsin / Q000032:analysis; D000511:alpha-Macroglobulins / Q000032:analysis
chemical_list: D011480:Protease Inhibitors; D000514:alpha 1-Antichymotrypsin; D000515:alpha 1-Antitrypsin; D000511:alpha-Macroglobulins