title: A comparison of lexical-semantic impairments in left hemisphere stroke and Alzheimer's disease.
abstract: Patients with aphasia due to left hemisphere stroke and patients with Alzheimer's disease, who were matched for severity of naming impairment, were compared on tests of lexical-semantic processing. The results suggest that the lexical-semantic impairments in both groups are due to a combination of impaired access to, and loss of, lexical-semantic information, but that impaired access is more prominent in stroke patients, whereas Alzheimer's disease patients suffer a greater loss of information. The results are discussed in terms of a brain model of the storage and processing of lexical-semantic information, and with respect to implications for treatment strategies.
authors: Department of Psychiatry, University of Pittsburgh, PA 15213.
authors: F J
authors: FJ
authors: Huff
authors: L
authors: L
authors: Mack
authors: J
authors: J
authors: Mahlmann
authors: S
authors: S
authors: Greenberg
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000523:psychology*; D000849:Anomia / Q000523:psychology; D001037:Aphasia / Q000523:psychology*; D002544:Cerebral Infarction / Q000523:psychology*; D004292:Dominance, Cerebral; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D010364:Pattern Recognition, Visual; D010700:Phonetics; D012660:Semantics; D014936:Word Association Tests