title: Fibreoptic bronchoscopy: an assessment of immediate cytological diagnosis using methylene blue stain.
abstract: A method of examining cytological material during fibreoptic bronchoscopy using a methylene blue (MB) stain was assessed in 164 consecutive fibreoptic bronchoscopies where cytology specimens were taken. The MB method provided an immediate positive diagnosis in 86% of bronchoscopically visible tumours. Subsequent histology provided a positive diagnosis in 69%, conventional brush cytology in 81% and trap cytology in 77%. The MB method produced no false positive diagnosis of malignancy and the tumour cell type identified by MB stain agreed with the histological cell type in 72% of cases. This technique is considered to be sufficiently specific to provide a method of controlling the quality of specimens taken at bronchoscopy, for further analysis in the laboratory.
authors: Regional Cell Pathology Service, Wandle Valley Hospital, Mitcham Junction, Surrey, U.K.
authors: I
authors: I
authors: Titley
authors: R N
authors: RN
authors: Davidson
authors: E
authors: E
authors: Turner
authors: E R
authors: ER
authors: Hicks
authors: N T
authors: NT
authors: Cooke
authors: W N
authors: WN
authors: Landells
authors: M M
authors: MM
authors: Levene
mesh_terms: D001984:Bronchial Neoplasms / Q000175:diagnosis*; D001999:Bronchoscopy / Q000379:methods*; D003581:Cytodiagnosis / Q000379:methods*; D005336:Fiber Optic Technology; D006801:Humans; D008751:Methylene Blue; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D013194:Staining and Labeling
chemical_list: D008751:Methylene Blue