[Chemotherapy and partial surgery in epithelioma of the pharyngo-larynx].
On the basis of a series of 185 patients, the authors evaluate the results of the therapeutic sequence chemotherapy-partial surgery in carcinomas of the pharyngolarynx. The action of chemotherapy is confirmed (80% clinical responses greater than 50%, 55% residual tumours or in complete histological regression). The therapeutic sequence chemotherapy-surgery gave 25% local failures and 1% lymph node failures. The development of the therapeutic strategy in carcinomas of the pharyngolarynx is considered in relation to the action of current modalities of chemotherapy.
Laccourreye
H
H
Service d'Oto-Rhino-Laryngologie, Hôpital Laënnec, Paris.
Bonfils
P
P
Brasnu
D
D
Ménard
M
M
Fabre
A
A
Janot
F
F
Bassot
V
V
D000206:Actuarial Analysis; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage; D002277:Carcinoma / Q000628:therapy*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007822:Laryngeal Neoplasms / Q000628:therapy*; D008207:Lymphatic Metastasis; D008727:Methotrexate / Q000008:administration & dosage; D010610:Pharyngeal Neoplasms / Q000628:therapy*
D001761:Bleomycin; D002945:Cisplatin; D005472:Fluorouracil; D008727:Methotrexate
Chimiothérapie et chirurgie partielle dans les épithéliomas du pharyngo-larynx.