Immunoglobulin subclasses in chronic tonsillitis.
The distribution and proportion of immunoglobulin-producing cells in palatine tonsil, including IgG and IgA subclasses, have been examined in chronic tonsillitis using an immunofluorescence method. Results obtained indicate that the percentage ratios of IgG1:IgG2:IgG3:IgG4 were 53.1:35.9:4.7:6.3. Higher percentages of IgG1- and lower percentages of IgG2-producing cells were found among 3 types of tonsillitis. Proportional ratios of IgA1:IgA2 were approximately 80:20, and a slight elevation of IgA2-producing cells was observed in chronic tonsillitis.
Moro
I
I
Department of Pathology, Nihon University School of Dentistry, Tokyo, Japan.
Komiyama
K
K
Iwase
T
T
Kusama
K
K
Asano
M
M
Takahashi
T
T
Okamura
N
N
D000921:Antibody-Producing Cells / Q000473:pathology*; D002452:Cell Count; D002908:Chronic Disease; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis / Q000145:classification*; D007074:Immunoglobulin G / Q000032:analysis / Q000145:classification*; D007150:Immunohistochemistry; D014066:Palatine Tonsil / Q000473:pathology; D012871:Skin Diseases / Q000473:pathology; D013194:Staining and Labeling; D014069:Tonsillitis / Q000473:pathology*
D007070:Immunoglobulin A; D007074:Immunoglobulin G