title: Chrysanthemum virus B: antibodies to structural protein in mammals and Mg2(+)-dependent reverse-transcriptase activity.
abstract: Human plasma has been found to contain antibodies reacting with the structural protein of chrysanthemum virus B (CV-B) and about 10 times less intensively with the structural protein of another carlavirus, the potato virus M. It has been shown that the antibodies bind to CV-B through their F(ab)2 fragments. No reaction with proteins of other plant viruses or retroviruses was observed. Antibodies reacting with CV-B protein are also present in the plasma of green monkey, goat, rabbit, and mouse, their level being somewhat lower than in man. In addition, Mg2(+)-dependent reverse transcriptase activity reaching maximum at 37 degrees C was detected in the CV-B preparations. It is suggested that humans and the mammals in question developed antibodies to CV-B which could enter into some enzymatic reactions at the body temperature.
authors: All-Union Oncological Centre, U.S.S.R. Academy of Medical Sciences, Moscow.
authors: V A
authors: VA
authors: Morozov
authors: P O
authors: PO
authors: Ilyinskii
authors: K V
authors: KV
authors: Ilyin
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D002522:Chlorocebus aethiops; D011723:Chrysanthemum cinerariifolium / Q000382:microbiology; D006041:Goats; D006801:Humans; D008274:Magnesium; D051379:Mice; D010942:Plant Viruses / Q000201:enzymology / Q000276:immunology* / Q000302:isolation & purification; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism*; D011817:Rabbits; D012190:Retroviridae / Q000276:immunology; D015678:Viral Structural Proteins / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D015678:Viral Structural Proteins; D012194:RNA-Directed DNA Polymerase; D008274:Magnesium