[Anthrax toxin dynamics in the body].
Anthrax toxin introduced subcutaneously into white rats Fisher-344 caused specific intoxication accompanied by characteristic pathomorphological changes and, when studied by the immunoperoxidase method in histological sections, could be detected in the blood stream (in plasma) and in the cytoplasm of macrophages (in the lungs and the spleen). The content of the preparation introduced into the animals in the blood stream is directly related to its toxicity, being probably indicative of the relative functional failure of the macrophagal system.
Golubinskiĭ
E P
EP
Tafel'shteĭn
E E
EE
Kolesnik
V S
VS
Osipenko
I I
II
Kondrat'eva
A M
AM
D000818:Animals; D000881:Anthrax / Q000209:etiology / Q000276:immunology / Q000473:pathology; D000942:Antigens, Bacterial / Q000032:analysis; D001408:Bacillus anthracis / Q000276:immunology; D001427:Bacterial Toxins / Q000032:analysis / Q000633:toxicity*; D000939:Epitopes / Q000032:analysis; D007124:Immunoenzyme Techniques; D008264:Macrophages / Q000276:immunology; D051381:Rats; D011916:Rats, Inbred F344
D000942:Antigens, Bacterial; D001427:Bacterial Toxins; D000939:Epitopes; C030325:anthrax toxin
O dinamike sibireiazvennogo toksina v organizme.