title: [Malignant mesodermal mixed tumor of the bladder: report of a case].
abstract: An 81-year-old woman was admitted to our clinic due to gross hematuria. A large bulky pedunculated mass was found in the bladder by cystoscopic examination. Subtotal cystectomy and bilateral cutaneostomy was performed on January 12, 1987. Histologically the tumor was composed of carcinomatous and sarcomatous elements. The carcinomatous element was composed fundamentally of grade 2, transitional cell carcinoma with numerous foci of squamous metaplasia. The sarcomatous element was composed of myxosarcomatous, chondro-sarcomatous pattern and non-differentiated malignant spindle cell component. Immunohistochemical examination demonstrated the presence of cytokeratin and epithelial membrane antigen in the spindle cell and more obvious carcinomatous regions, using the avidin-biotin conjugated immunoperoxidase technique. The patient died 3 months after operation. Autopsy findings showed multiple organ metastasis which were composed of carcinomatous and sarcomatous elements.
authors: Department of Urology, Aichi Medical University.
authors: Y
authors: Y
authors: Yamada
authors: H
authors: H
authors: Yamada
authors: Y
authors: Y
authors: Miyagawa
authors: H
authors: H
authors: Nonomura
authors: Y
authors: Y
authors: Hatano
authors: M
authors: M
authors: Waki
authors: S
authors: S
authors: Hiraiwa
authors: T
authors: T
authors: Muramatsu
authors: E
authors: E
authors: Nishikawa
authors: T
authors: T
authors: Satou
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000951:Antigens, Neoplasm / Q000032:analysis; D005260:Female; D006801:Humans; D007633:Keratins / Q000032:analysis; D008562:Membrane Glycoproteins; D018396:Mucin-1; D009373:Neoplasms, Germ Cell and Embryonal / Q000032:analysis / Q000473:pathology*; D001749:Urinary Bladder Neoplasms / Q000032:analysis / Q000473:pathology*
chemical_list: D000951:Antigens, Neoplasm; D008562:Membrane Glycoproteins; D018396:Mucin-1; D007633:Keratins