title: Diagnosis and differentiation of von Willebrand's disease type II.
abstract: Out of 113 patients with vWD 15 were of type II. The basic test programme included F VIII:C, vWF-Ag, RCF and BT (Ivy). All type II patients had relatively high vWF-Ag and low RCF values. CIEP proved increased anodal migration velocity. IRMA testing of vWF:Ag was showing narrow correlation with RCF. Thrombocyte count was unchanged after DDAVP infusion and RIPA was always diminished. Finally multimeric sizing was done in 6 patients. From the completely diagnosed patients 5 are of type IIA and one seems to have type IIC. Nobody of the 15 had the characteristics of type IIB.
authors: Department of Paediatrics, Karl-Marx-University Leipzig, GDR.
authors: H
authors: H
authors: Lenk
authors: I M
authors: IM
authors: Nilsson
authors: L
authors: L
authors: Holmberg
authors: G
authors: G
authors: Weissbach
mesh_terms: D000941:Antigens / Q000032:analysis; D001760:Bleeding Time; D003894:Deamino Arginine Vasopressin; D006801:Humans; D014842:von Willebrand Diseases / Q000175:diagnosis*; D014841:von Willebrand Factor / Q000276:immunology
chemical_list: D000941:Antigens; C029417:Von Willebrand antigen; D014841:von Willebrand Factor; D003894:Deamino Arginine Vasopressin