[Acute lymphatic leukemia with pre-B-cell characteristics].
54 patients affected with acute lymphatic leukaemia (ALL) in the period from 1978-1984 were examined concerning the frequency of pre-B-ALL in comparison with other immunological subtypes of ALL. For this purpose the following markers were tested: 1. Cytoplasmatic IgM 2. Rosette formation with sheep erythrocytes 3. T-cell specific antigen 4. C-ALL antigen 5. Surface immunoglobulin By means of these markers the patients were divided into 5 immunological subtypes of ALL, viz. 1. Pre-B-ALL (16.6%) 2. O-ALL (37.1%) 3. C-ALL (27.9%) 4. T-ALL (16.6%) 5. B-ALL (1.8%) The immunological subtypes of ALL were compared by means of clinical parameters (age, initial leukocyte number, mediastinal tumor, initial CNS involvement). No difference could be detected between O-ALL, pre-B-ALL and C-ALL, whereas T-ALL showed a distinctly worse prognosis.
Sauerbrey
A
A
Universitäts-Kinderklinik und Poliklinik Jussuf Ibrahim Jena.
Häfer
R
R
Zintl
F
F
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D003593:Cytoplasm / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D005859:Germany, East; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007223:Infant; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000175:diagnosis; D008297:Male; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000401:mortality
D007074:Immunoglobulin G
Akute lymphatische Leukämie mit Prä-B-Zell-Charakteristik.