Antibodies as probes of the structure and function of the nicotinic acetylcholine receptor.
Structural and functional studies of the nicotinic acetylcholine receptor from Torpedo marmorata are discussed as examples for the distinct differences in properties of antibodies raised against a native antigen as compared to antibodies raised against short or long synthetic peptides.
Maelicke
A
A
Max-Planck-Institut für Ernährungsphysiologie, Dortmund, FRG.
Fels
G
G
Plümer-Wilk
R
R
Schreiber
M
M
D000494:Allosteric Regulation; D000818:Animals; D000906:Antibodies / Q000276:immunology*; D000918:Antibody Specificity; D000939:Epitopes / Q000138:chemical synthesis / Q000276:immunology; D010446:Peptide Fragments / Q000138:chemical synthesis / Q000276:immunology; D011978:Receptors, Nicotinic / Q000276:immunology*; D013045:Species Specificity; D014101:Torpedo
D000906:Antibodies; D000939:Epitopes; D010446:Peptide Fragments; D011978:Receptors, Nicotinic