Treatment of "intractable childhood epilepsy" with high doses of intravenous gamma-globulins.
The authors refer their experience in the treatment of intractable childhood epilepsies (18 cases) with intravenous gamma globulin. Seven patients showed great reduction or indeed disappearance of the seizures whereas modest improvement was observed in other 4 cases. A better organization of the EEG corresponded to this clinical improvement with a reduction or disappearance of paroxysmal anomalies, and also a better result in motor and cognitive capacities.
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D000927:Anticonvulsants / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D004827:Epilepsy / Q000188:drug therapy / Q000628:therapy*; D005260:Female; D006801:Humans; D007116:Immunization, Passive; D007223:Infant; D007275:Injections, Intravenous; D008297:Male; D005719:gamma-Globulins / Q000008:administration & dosage*
D000927:Anticonvulsants; D005719:gamma-Globulins