[Spontaneous hepatomas in hybrid mice (CBA x C57Bl/6)F1].
The spontaneous hepatomas of male mice (CBA X C57B1/6)F1 were studied using complex cytologic, histologic, immunochemical, and cytochemical methods. The AFP was detected in trace amount in the serum of tumour-bearing mice and in single cells of hepatomas. As a rule the hepatocarcinoma cells have the polymodal DNA distribution (2C-8C) with major peak of 4 C (in 18 out of 26 cases). More rarely the tumours with predominant diploid and octoploid cells were observed.
Khar'kovskaia
N A
NA
Shipova
L Ia
LIa
Faktor
V M
VM
Khrustalev
S A
SA
D000818:Animals; D004273:DNA, Neoplasm / Q000032:analysis; D007124:Immunoenzyme Techniques; D007150:Immunohistochemistry; D008099:Liver / Q000032:analysis / Q000378:metabolism / Q000473:pathology; D008114:Liver Neoplasms, Experimental / Q000032:analysis / Q000378:metabolism / Q000473:pathology*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D000509:alpha-Fetoproteins / Q000032:analysis
D004273:DNA, Neoplasm; D000509:alpha-Fetoproteins
Issledovanie spontannykh gepatom mysheĭ-gibridov (CBA x C57Bl/6)F1.