Catalysis by the RNA subunit of RNase P--a minireview.
RNase P, an enzyme that contains both RNA and protein components, cleaves tRNA precursors to generate mature 5' termini. The catalytic activity of RNase P resides in the RNA component, with the protein cofactor affecting the rate of the cleavage reaction. The reaction is also influenced by the nature of the tRNA substrate.
Altman
S
S
Department of Biology, Yale University, New Haven, CT 06520.
Baer
M F
MF
Bartkiewicz
M
M
Gold
H
H
Guerrier-Takada
C
C
Kirsebom
L A
LA
Lumelsky
N
N
Peck
K
K
D002384:Catalysis; D004722:Endoribonucleases / Q000502:physiology*; D009690:Nucleic Acid Conformation; D012313:RNA / Q000502:physiology*; D012322:RNA Precursors / Q000378:metabolism*; D012326:RNA Splicing; D012338:RNA, Ribosomal, 23S / Q000378:metabolism; D043262:Ribonuclease P; D013379:Substrate Specificity
D012322:RNA Precursors; D012338:RNA, Ribosomal, 23S; D012313:RNA; D004722:Endoribonucleases; D043262:Ribonuclease P