title: Fundamental considerations in pacing of the diaphragm for chronic ventilatory insufficiency: a multi-center study.
abstract: Records were reviewed of 477 patients who had diaphragm pacemakers implanted for treatment of chronic hypoventilation. Three groups were established for comparison. (1) Center group: 165 patients operated on in six medical centers participating in a cooperative study; (2) Noncenter group, sufficient data available: 203 patients operated on by surgeons with experience limited to a few cases; (3) Nonstudy group, minimal data available: 109 patients operated on as in group 2; vital statistics only were contributed. The protocol for data gathering was comprised of 154 major variables. Basic data on age, sex, diagnosis and etiology were analyzed for homogenicity of data among the groups. A comprehensive analysis of the pacing methods, complication and results from the Center group yielded information on the early experience with diaphragm pacing important to its future application.
authors: Department of Surgery, Yale University School of Medicine, New Haven, CT 06510.
authors: W W
authors: WW
authors: Glenn
authors: R T
authors: RT
authors: Brouillette
authors: B
authors: B
authors: Dentz
authors: H
authors: H
authors: Fodstad
authors: C E
authors: CE
authors: Hunt
authors: T G
authors: TG
authors: Keens
authors: H M
authors: HM
authors: Marsh
authors: S
authors: S
authors: Pande
authors: D G
authors: DG
authors: Piepgras
authors: R G
authors: RG
authors: Vanderlinden
mesh_terms: D003964:Diaphragm / Q000294:innervation*; D004599:Electric Stimulation Therapy / Q000295:instrumentation*; D006801:Humans; D007040:Hypoventilation / Q000628:therapy*; D015337:Multicenter Studies as Topic; D010791:Phrenic Nerve / Q000502:physiology*; D012131:Respiratory Insufficiency / Q000628:therapy*