Cerebrospinal fluid levels of beta-endorphin in patients with fibromyalgia (fibrositis syndrome).
Cerebrospinal fluid (CSF) samples from 18 female patients with fibromyalgia (fibrositis syndrome) were analyzed for beta-endorphin. The mean CSF level of beta-endorphin was 20.7 +/- 0.7 fmol/ml in the patients compared to 20.5 +/- 2.0 fmol/ml (mean +/- SEM) in healthy controls (p greater than 0.05). Thus, patients with fibromyalgia (fibrositis syndrome) seem to have normal CSF levels of the pain modulatory neuropeptide beta-endorphin.
Vaeroy
H
H
Department of Rheumatology Oslo Sanitetsforenings Rheumatism Hospital, Norway.
Helle
R
R
Førre
O
O
Kåss
E
E
Terenius
L
L
D000328:Adult; D005260:Female; D005356:Fibromyalgia / Q000134:cerebrospinal fluid*; D006801:Humans; D008875:Middle Aged; D011863:Radioimmunoassay; D013373:Substance P / Q000134:cerebrospinal fluid; D001615:beta-Endorphin / Q000134:cerebrospinal fluid*
D013373:Substance P; D001615:beta-Endorphin