[Structural changes in hepatocytes during rheopolyglucine administration and subsequent stress in mice].
A lysosomotropic agent rheopolyglucine was injected intravenously to male CBA mice at a dose of 1 ml per 100 g body weight. Two hours later hepatocyte hypertrophy and cytoplasmic organoid hyperplasia were observed. The exposure of these mice to acute stress did not lead to catabolic changes in hepatocytes.
Shkurupiĭ
V A
VA
D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D003911:Dextrans / Q000494:pharmacology*; D008099:Liver / Q000166:cytology* / Q000187:drug effects / Q000648:ultrastructure; D008115:Liver Regeneration; D008247:Lysosomes / Q000187:drug effects / Q000648:ultrastructure; D008297:Male; D051379:Mice; D008930:Mitochondria, Liver / Q000648:ultrastructure; D013312:Stress, Physiological / Q000473:pathology*
D003911:Dextrans
Strukturnye preobrazovaniia v gepatotsitakh pri vvedenii mysham reopoligliukina i posleduiuschchem vozdeĭstvii stressa.