Colocalization of substance P and gamma-aminobutyric acid in amacrine cells of the cat retina.
Substance P and gamma-aminobutyric acid (GABA) were colocalized by immunocytochemistry in two subpopulations of amacrine cells in the cat retina. All of the cells which stained for substance P also showed GABA reactivity. However, there were many GABA-immunoreactive cells which did not stain for substance P. The presence of neuropeptides provides a basis for additional neurochemical characterization of the multiple populations of GABA immunoreactive cells.
Pourcho
R G
RG
Department of Anatomy and Cell Biology, Wayne State University, Detroit, MI 48201.
Goebel
D J
DJ
D000818:Animals; D000911:Antibodies, Monoclonal; D002415:Cats; D005455:Fluorescent Antibody Technique; D012160:Retina / Q000166:cytology*; D013373:Substance P / Q000032:analysis*; D005680:gamma-Aminobutyric Acid / Q000032:analysis*
D000911:Antibodies, Monoclonal; D013373:Substance P; D005680:gamma-Aminobutyric Acid