Neuropeptides and inflammation: the role of substance P.
The neuropeptide substance P modulates the activities of a number of different leukocytes that characterize both acute and delayed inflammatory responses. Substance P may play a role in the pathogenesis of such diverse diseases as arthritis, asthma, and inflammatory bowel disease.
Payan
D G
DG
Howard Hughes Medical Institute, San Francisco, California.
D000818:Animals; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000503:physiopathology; D006969:Hypersensitivity, Immediate / Q000503:physiopathology; D007249:Inflammation / Q000503:physiopathology*; D012157:Mononuclear Phagocyte System / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D018040:Receptors, Neurokinin-1; D017981:Receptors, Neurotransmitter / Q000187:drug effects; D013373:Substance P / Q000502:physiology*
D018040:Receptors, Neurokinin-1; D017981:Receptors, Neurotransmitter; D013373:Substance P