title: [The action of interferon preparations on strains of Legionella of various serogroups and species].
abstract: The action of different preparations of interferon on Legionella strains has been studied in vivo and in vitro. The preparations of leukinferon at a concentration of 500 international units (I.U.) and reaferon at a concentration of 10,000 I.U. have been found to produce an inhibiting effect on Legionella strains in vitro, in a medium with carbon-yeast agar. Leukinferon at a concentration of 125 I.U. suppresses the growth of L. pneumophila also in a liquid medium. The preparation of leukinferon at a minimal concentration of 100 I.U. has been found to suppress the development of lethal infection in chick embryos infected with L. pneumophila strain Philadelphia 1.
authors: I S
authors: IS
authors: Tartakovskiĭ
authors: B I
authors: BI
authors: Marakusha
authors: V V
authors: VV
authors: Kuznetsov
authors: L V
authors: LV
authors: Nebozhina
authors: S V
authors: SV
authors: Prozorovskiĭ
mesh_terms: D000818:Animals; D002642:Chick Embryo; D004305:Dose-Response Relationship, Drug; D004917:Erythromycin / Q000494:pharmacology; D007372:Interferons / Q000494:pharmacology*; D007875:Legionella / Q000145:classification / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D012703:Serotyping; D013045:Species Specificity
chemical_list: D004917:Erythromycin; D007372:Interferons
vernacular_title: Deĭtsvie preparatov interferona na shtammy legionell razlichnykh serogrupp i vidov.