Inhibition of herpes simplex virus type 1 (HSV-1) plaque enlargement by neutralizing sera.
The inhibitory activity of neutralizing sera on Herpes simplex virus type 1 (HSV-1) plaque enlargement (PE) is easily detected using the S variant of low passage clinical isolates (Mannini-Palenzona et al., 1985b; Costanzo et al., 1986). The same sera show little or no activity on PE of the product of the S variant rapid in vitro conversion, the L variant, and laboratory strains HSV-1 (F) and (MP). No significant difference was found in the inhibitory activity of sera from healthy individuals with no history of recurrence and patients with recurrences.
Mannini-Palenzona
A
A
Dipartimento di Patologia-Sperimentale, University of Bologna, Italy.
Costanzo
F
F
Foà-Tomasi
L
L
Negosanti
M
M
Lanzoni
A
A
D000328:Adult; D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D003470:Culture Media; D006561:Herpes Simplex / Q000276:immunology*; D006801:Humans; D007106:Immune Sera / Q000276:immunology; D007223:Infant; D007372:Interferons / Q000032:analysis; D008875:Middle Aged; D009500:Neutralization Tests; D012008:Recurrence; D018139:Simplexvirus / Q000254:growth & development / Q000276:immunology*; D014709:Vero Cells
D000914:Antibodies, Viral; D003470:Culture Media; D007106:Immune Sera; D007372:Interferons