Smallest zinc quantities affect the histamine release from peritoneal mast cells of the rat.
Seven individual 0.025-mg doses of zinc administered as lactose tablets on consecutive days, significantly increase histamine release from peritoneal mast cells of the rat. Seven individual doses of 0.25 microgram caused a somewhat smaller, though still very pronounced increase in the release in comparison with zero control.
Harisch
G
G
Institut für Physiologische Chemie, Tierärztliche Hochschule Hannover, Federal Republic of Germany.
Kretschmer
M
M
D000818:Animals; D004305:Dose-Response Relationship, Drug; D006636:Histamine Release / Q000187:drug effects*; D008407:Mast Cells / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains; D015032:Zinc / Q000494:pharmacology*
D015032:Zinc