Nodular bleomycin toxicity.
Pulmonary interstitial fibrosis, a well-known toxic effect of bleomycin therapy, usually presents radiographically as diffuse reticularity. The authors report an unusual case of biopsy-proven bleomycin toxicity that presented as pulmonary nodules mimicking metastatic tumor. The histologic findings resembled those seen in the diffuse form of toxicity but notably also included foci of bronchiolitis obliterans.
Cohen
M B
MB
Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, New York 10032.
Austin
J H
JH
Smith-Vaniz
A
A
Lutzky
J
J
Grimes
M M
MM
D000328:Adult; D001761:Bleomycin / Q000009:adverse effects*; D003937:Diagnosis, Differential; D006801:Humans; D008171:Lung Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D011859:Radiography
D001761:Bleomycin