Experimental studies on the pathogenesis of retinopathy of prematurity.
The angiogenic activity of various parts of the retina in kittens with oxygen-induced retinopathy has been studied by the use of a corneal micropocket technique and chorioallantoic assay. The results indicate that in retinopathy of prematurity the most important role in the pathogenesis of fibrovascular proliferation is played by the so-called primary avascular retina, that is, that part of the retina which has not yet been vascularised during ontogenesis.
Prost
M
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Clinic of Ophthalmology, Medical Academy, Lublin, Poland.
D000818:Animals; D002415:Cats; D005321:Extraembryonic Membranes / Q000098:blood supply; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009389:Neovascularization, Pathologic / Q000473:pathology; D012171:Retinal Vessels / Q000473:pathology*; D012178:Retinopathy of Prematurity / Q000209:etiology* / Q000473:pathology