[Serotonin modulation of glycine-induced ionic currents in mollusk neurons].
It was found that serotonin decreases glycine-induced response in Helix pomatia neurons. The Ca2+ injection into the cell increased glycine-induced currents, i.e. the type of modulating serotonin action on the glycine-induced response was changed. Effects of theophylline, dibutyryl-cAMP and imidazole on glycine-induced currents indicated that the cyclase system of the nerve cell was involved in the bimodal action of serotonin of glycine-induced ionic currents.
Diatlov
V A
VA
D000818:Animals; D003994:Bucladesine / Q000494:pharmacology; D002118:Calcium / Q000494:pharmacology; D005998:Glycine / Q000494:pharmacology*; D007093:Imidazoles / Q000494:pharmacology; D066298:In Vitro Techniques; D007473:Ion Channels / Q000187:drug effects* / Q000502:physiology; D008974:Mollusca / Q000502:physiology*; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D012701:Serotonin / Q000502:physiology*; D013806:Theophylline / Q000494:pharmacology
D007093:Imidazoles; D007473:Ion Channels; D012701:Serotonin; D003994:Bucladesine; D013806:Theophylline; D002118:Calcium; D005998:Glycine
Moduliatsiia serotoninom glitsin-indutsiruemykh ionnykh tokov v neĭronakh molliuska.