[Intermediate thalassemia. Study of 5 cases in their clinical, ferrokinetic and erythrokinetic aspects].
Five cases of thalassaemia intermedia are reported, they being considered from clinical and biologic standpoints. All patients had long-lasting anaemia, variable enlargement of spleen and low transfusion requirements. The ferro-erythrokinetic pattern was that of chronic haemolysis with effective erythropoiesis, and some comments are included on the different patterns found in each genetic variety. None of the patients is subjected to a defined transfusion protocol.
Muñoz
J A
JA
Martín
M V
MV
Risueño
C E
CE
Freire
J
J
Pajares
M
M
Campos
J
J
D004200:Diseases in Twins; D004920:Erythropoiesis; D005319:Fetal Hemoglobin / Q000032:analysis; D005914:Globins / Q000235:genetics; D006443:Hemoglobin A2 / Q000032:analysis; D006444:Hemoglobin C / Q000032:analysis; D006445:Hemoglobin C Disease / Q000097:blood* / Q000150:complications / Q000235:genetics; D006801:Humans; D007501:Iron / Q000097:blood; D010375:Pedigree; D013163:Splenomegaly / Q000209:etiology; D013789:Thalassemia / Q000097:blood* / Q000150:complications / Q000235:genetics
D005914:Globins; D006444:Hemoglobin C; D006443:Hemoglobin A2; D005319:Fetal Hemoglobin; D007501:Iron
Talasemia intermedia. Estudio de cinco casos en sus aspectos clínicos, ferrocinéticos y eritrocinéticos.