Parvicellular adrenergic neurons receive substance P-ergic inputs in the nucleus of the tractus solitarius of the rat.
Synaptic interaction between parvicellular adrenergic neurons and substance P (SP) afferents in the caudal part of the nucleus of the tractus solitarius (NTS) was demonstrated by the immunoelectron microscopic mirror method, using antisera against phenylethanolamine N-methyltransferase (PNMT) and SP. SP-immunoreactive (SP-IR) terminals formed synaptic contacts with PNMT-IR neurons. It is suggested that SP afferents directly affect parvicellular adrenergic neurons via synapse in the NTS.
Kawai
Y
Y
1st Department of Anatomy, Osaka City University Medical School, Japan.
Takagi
H
H
D000320:Adrenergic Fibers / Q000502:physiology* / Q000648:ultrastructure; D000818:Animals; D007150:Immunohistochemistry; D008297:Male; D008526:Medulla Oblongata / Q000166:cytology / Q000378:metabolism*; D008854:Microscopy, Electron; D051381:Rats; D011919:Rats, Inbred Strains; D013373:Substance P / Q000378:metabolism*
D013373:Substance P