Choroidal neovascular membrane and other chorioretinal complications of acquired syphilis.
We reviewed ten patients who had posterior segment complications of acquired syphilis. Five of these patients had a neovascular membrane of the choroid associated with secondary or tertiary syphilis. Vision was stabilized after laser photocoagulation in one patient who had a choroidal neovascular membrane. Five additional patients had ocular manifestations including uveitis, optic neuritis, neuroretinitis, chorioretinitis, retinal hemorrhages, arterial and venous occlusion, vasculitis, and retinitis. Treatment of chorioretinal complications of syphilis with intravenous penicillin, if initiated early in the course of the disease, may result in excellent visual recovery.
Halperin
L S
LS
Department of Ophthalmology, Washington University School of Medicine, St. Louis, MO.
Lewis
H
H
Blumenkranz
M S
MS
Gass
J D
JD
Olk
R J
RJ
Fine
S L
SL
D000328:Adult; D002829:Choroid / Q000098:blood supply*; D015862:Choroid Diseases / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008028:Light Coagulation; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000473:pathology; D010406:Penicillins / Q000627:therapeutic use; D012164:Retinal Diseases / Q000188:drug therapy / Q000209:etiology*; D013587:Syphilis / Q000150:complications* / Q000188:drug therapy; D014792:Visual Acuity
D010406:Penicillins