Structure and function of prostatic- and seminal vesicle-secreted proteins involved in the gelation and liquefaction of human semen.
At ejaculation, the epididymal spermatozoa mix with the secretions produced by the seminal vesicles and the prostate. The glandular secretions immediately turns into a gel-like structure which entraps the spermatozoa. The ejaculated spermatozoa become progressively motile as the gel dissolves. The discovery, structure, and interactions of proteins involved in these post-ejaculatory phase reactions of semen are here reported.
Lilja
H
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Department of Clinical Chemistry, University of Lund, Malmö General Hospital, Sweden.
D000595:Amino Acid Sequence; D000951:Antigens, Neoplasm / Q000502:physiology*; D003001:Cloning, Molecular; D005782:Gels; D012739:Gonadal Steroid Hormones / Q000502:physiology*; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D008970:Molecular Weight; D011467:Prostate / Q000502:physiology*; D017430:Prostate-Specific Antigen; D012661:Semen / Q000502:physiology*; D029607:Seminal Vesicle Secretory Proteins; D012669:Seminal Vesicles / Q000502:physiology*; D013081:Sperm Motility; D013329:Structure-Activity Relationship
D000951:Antigens, Neoplasm; D005782:Gels; D012739:Gonadal Steroid Hormones; D029607:Seminal Vesicle Secretory Proteins; C424482:seminal vesicle-specific antigen; D017430:Prostate-Specific Antigen