Dark-rearing modifies serotonin and 5-hydroxyindoleacetic acid contents in specific regions of rabbit brain.
The contents of serotonin (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) in specific brain regions of rabbits dark-reared from birth until 3 months of age are higher than those of controls. After light exposure, 5-HT and 5-HIAA levels become similar to normal values. In adult rabbits kept in darkness for 3 months, 5-HT and 5-HIAA contents increase only in the superior colliculi. These results are discussed in relation to the early development of the vestibulo-ocular reflex.
Alesci
R
R
Dipartimento di Fisiologia e Biochimica, Università di Pisa, Italy.
La Noce
A
A
Bagnoli
P
P
Ghelarducci
B
B
D000344:Afferent Pathways; D000818:Animals; D001921:Brain / Q000502:physiology*; D002531:Cerebellum / Q000502:physiology; D003623:Dark Adaptation; D005260:Female; D006897:Hydroxyindoleacetic Acid / Q000502:physiology*; D008297:Male; D009473:Neuronal Plasticity; D011817:Rabbits; D011985:Receptors, Serotonin / Q000502:physiology; D012027:Reflex, Vestibulo-Ocular; D012701:Serotonin / Q000502:physiology*
D011985:Receptors, Serotonin; D012701:Serotonin; D006897:Hydroxyindoleacetic Acid