title: [Isolated symplasts and stromal syncytial buds of the normal human placenta at 6 to 14 weeks of pregnancy].
abstract: Formation of isolated symplasts (IS) ("deported trophoblast", according to English nomenclature) and stromal syncytial buds (SSB) has been studied in 10 normal patients at pregnancy of 6-14 weeks by means of the indirect immunoperoxidase method. Monoclonal antibodies against beta-subunit of the human chorionic gonadotropin (beta-HCG), serial paraffin slices, stained with hematoxylin-eosin, semithin slices, stained with toluidin blue-pyronine and scanning electron microscopy have been used. A great amount of syncytiotrophoblastic processes and IS, analogous by their structure to syncytiotrophoblast are revealed. Presence of beta-HCG in the syncytiotrophoblast and its absence in the cytotrophoblast are proved. Concentration of beta-HCG in the IS is higher than in the syncytiotrophoblast of the villi. Maximal concentration of beta-HCG in the SSB is described for the first time. The functional role of the IS and SSB is discussed in the system mother-placenta-fetus.
authors: I N
authors: IN
authors: Voloshchuk
authors: R
authors: R
authors: Fidler
authors: A P
authors: AP
authors: Milovanov
authors: M Sh
authors: MSh
authors: Verbitskiĭ
authors: O Iu
authors: OIu
authors: Zakharova
mesh_terms: D002459:Cell Fusion; D006063:Chorionic Gonadotropin / Q000378:metabolism; D018997:Chorionic Gonadotropin, beta Subunit, Human; D002824:Chorionic Villi / Q000378:metabolism / Q000648:ultrastructure*; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007124:Immunoenzyme Techniques; D010446:Peptide Fragments / Q000378:metabolism; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D012016:Reference Values
chemical_list: D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D010446:Peptide Fragments
vernacular_title: Izolirovannye simplasty i stromal'nye sintsitial'nye pochki normal'noĭ platsenty cheloveka pri 6--14 nedeliakh beremennosti.