Inhibition of human dihydrofolate reductase by antifolyl polyglutamates.
Kumar
P
P
Department of Biochemistry, Tufts University, Health Science Campus, Boston, MA 02111.
Kisliuk
R L
RL
Gaumont
Y
Y
Freisheim
J H
JH
Nair
M G
MG
D000630:Aminopterin / Q000031:analogs & derivatives* / Q000494:pharmacology; D005493:Folic Acid Antagonists / Q000494:pharmacology*; D006801:Humans; D008727:Methotrexate / Q000031:analogs & derivatives* / Q000494:pharmacology; D010455:Peptides / Q000494:pharmacology*; D011099:Polyglutamic Acid / Q000031:analogs & derivatives / Q000494:pharmacology*
D005493:Folic Acid Antagonists; D010455:Peptides; D011099:Polyglutamic Acid; C014085:methotrexate polyglutamate; C040210:edatrexate; D000630:Aminopterin; C017178:10-deazaaminopterin; D008727:Methotrexate