Secretion of amylase from the rat parotid salivary gland after degeneration of the auriculotemporal nerve.
The output of amylase into saliva secreted after injection of methacholine or substance P was increased after parasympathetic denervation, but the salivary concentration of amylase was unchanged. The increased output corresponded to the increased flow. Isoprenaline injected during the methacholine-induced secretion raised the output, more being secreted from the denervated than from the contralateral gland. Vasoactive intestinal peptide, given while substance P caused salivation, also increased the amylase output, but equally from the two glands.
Asking
B
B
Institute of Physiology and Biophysics, University of Lund, Sweden.
Emmelin
N
N
D000681:Amylases / Q000378:metabolism*; D000818:Animals; D007545:Isoproterenol / Q000494:pharmacology; D008297:Male; D008340:Mandibular Nerve / Q000502:physiology*; D016210:Methacholine Chloride; D008688:Methacholine Compounds / Q000494:pharmacology; D009410:Nerve Degeneration; D010306:Parotid Gland / Q000201:enzymology* / Q000294:innervation; D051381:Rats; D011919:Rats, Inbred Strains; D011941:Receptors, Adrenergic / Q000187:drug effects; D011976:Receptors, Muscarinic / Q000187:drug effects; D012463:Saliva / Q000201:enzymology / Q000378:metabolism; D013373:Substance P / Q000494:pharmacology; D014660:Vasoactive Intestinal Peptide / Q000494:pharmacology
D008688:Methacholine Compounds; D011941:Receptors, Adrenergic; D011976:Receptors, Muscarinic; D016210:Methacholine Chloride; D013373:Substance P; D014660:Vasoactive Intestinal Peptide; D000681:Amylases; D007545:Isoproterenol