title: Plasma substance P levels in fibrositis.
abstract: The mechanism of pain in the fibrositis syndrome is unknown. We measured plasma levels of substance P in 32 patients with fibrositis and 26 sex and age matched controls using a radioimmunoassay. The mean plasma level of substance P in the patients with fibrositis was 371 +/- 91 pg/ml and in controls 397 +/- 84 pg/ml (p = NS). We conclude that determination of plasma levels of substance P in fibrositis is of no diagnostic value. This does not exclude the possible role of substance P as a neurotransmitter in the fibrositis syndrome.
authors: Rheumatic Disease Unit, Toronto Western Hospital, University of Toronto, ON, Canada.
authors: W J
authors: WJ
authors: Reynolds
authors: B
authors: B
authors: Chiu
authors: R D
authors: RD
authors: Inman
mesh_terms: D000328:Adult; D005260:Female; D005356:Fibromyalgia / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D013373:Substance P / Q000097:blood*
chemical_list: D013373:Substance P