Signet ring cell carcinoma in a Schistosoma-infested bladder: case report and histochemical study.
A case of signet ring cell carcinoma of the urinary bladder with concomitant Schistosoma haematobium infection is reported with a histochemical study of mucous secretion. This rare kind of tumor differentiation in Schistosoma-related neoplasms may suggest that the tumor-promoting stimuli, acting on reserve cells of bladder epithelium, do not determine the tumor differentiation pattern as strictly as currently thought.
Bianco
P
P
Department of Human Biopathology, La Sapienza University, Rome, Italy.
Crescenzi
A
A
Savioli
L
L
D002288:Adenocarcinoma, Mucinous / Q000150:complications* / Q000378:metabolism; D006801:Humans; D008297:Male; D009093:Mucus / Q000378:metabolism; D012553:Schistosomiasis haematobia / Q000150:complications*; D013194:Staining and Labeling; D001749:Urinary Bladder Neoplasms / Q000150:complications* / Q000378:metabolism