title: UMC, another Cromer-related blood group antigen.
abstract: An antibody found in the serum of a Japanese blood donor detects a new high-frequency red cell antigen named UMC. UMC is absent from Inab phenotype cells, weakly expressed on Dr(a-) cells, and destroyed by alpha-chymotrypsin but not trypsin treatment of red cells. UMC is, therefore, a Cromer-related antigen. Immunoblotting with anti-UMC showed that UMC antigen, in common with other Cromer-related antigens, is carried on a red cell surface glycoprotein with an apparent molecular weight of 70,000, which presumably is the complement regulatory protein decay-accelerating factor.
authors: Medical Research Council Blood Group Unit, London, UK.
authors: G L
authors: GL
authors: Daniels
authors: Y
authors: Y
authors: Okubo
authors: H
authors: H
authors: Yamaguchi
authors: T
authors: T
authors: Seno
authors: M
authors: M
authors: Ikuta
mesh_terms: D000328:Adult; D001789:Blood Group Antigens / Q000235:genetics; D015153:Blotting, Western; D018958:CD55 Antigens; D004910:Erythrocyte Membrane / Q000276:immunology*; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D008562:Membrane Glycoproteins / Q000276:immunology*; D008565:Membrane Proteins / Q000276:immunology*; D008970:Molecular Weight; D010375:Pedigree
chemical_list: D001789:Blood Group Antigens; D018958:CD55 Antigens; D008562:Membrane Glycoproteins; D008565:Membrane Proteins