[Retrospective immunohistologic search for metastases using monoclonal anti-cytokeratin antibodies in lymph nodes of patients with stage Ib-IIb cervix cancer dying within 5 years].
With immunohistological methods using monoclonal antibodies more metastases were detected in carcinomas today. We examined 10 women, where the carcinoma of the cervix was removed today in healthy and where the lymph nodes were free of metastases. With use of the monoclonal cytokeratin-antibody lu-5 it was not possible to improve the diagnostic. In a histomorphological differentiation of grade 2 or 3 a radiation should be considered.
Domke
N
N
Klinik und Poliklinik für Gynäkologie und Geburtshilfe, Bezirkskrankenhauses, Görlitz.
Kasper
M
M
Stosiek
P
P
Bergander
S
S
D000328:Adult; D000911:Antibodies, Monoclonal; D003893:Desmin / Q000032:analysis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007124:Immunoenzyme Techniques; D007633:Keratins / Q000032:analysis*; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009367:Neoplasm Staging; D009360:Neoplastic Cells, Circulating; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000401:mortality / Q000473:pathology*; D014746:Vimentin / Q000032:analysis
D000911:Antibodies, Monoclonal; D003893:Desmin; D014746:Vimentin; D007633:Keratins
Retrospektive immunohistologische Metastasensuche mittels monoklonalem Anti-Zytokeratin-Antikörper an Lymphknoten von Zervixkarzinompatientinnen der Stadien Ib-IIb, die innerhalb von 5 Jahren verstarben.