title: Distribution of GABA-like immunoreactive neurons in the slug Limax maximus.
abstract: Immunohistochemical techniques were used to study the distribution of gamma-amino butyric acid (GABA)-like immunoreactive neurons in the nervous system of the slug Limax maximus. Approximately 170 GABA-like immunoreactive cell bodies were found in the central nervous system. These were located in the cerebral, buccal and pedal ganglia. Most GABA-like immunoreactive neurons had small cell bodies, which were aggregated into discrete clusters within the cerebral and pedal ganglia. Three pairs of longer, uniquely identifiable, GABA-like immunoreactive cells were found in the cerebral ganglion. GABA-like immunoreactive nerve fibres were also found in all of the central ganglia but were absent from peripheral nerves. These results suggest that GABA acts as a central neurotransmitter in the slug. The possible roles of GABA-ergic neurotransmission in the slug are discussed.
authors: Department of Biology, Princeton University, New Jersey.
authors: I R
authors: IR
authors: Cooke
authors: A
authors: A
authors: Gelperin
mesh_terms: D000818:Animals; D005247:Feeding Behavior / Q000502:physiology; D007150:Immunohistochemistry; D008974:Mollusca / Q000033:anatomy & histology*; D009412:Nerve Fibers / Q000648:ultrastructure; D009474:Neurons / Q000502:physiology / Q000648:ultrastructure*; D013194:Staining and Labeling; D005680:gamma-Aminobutyric Acid / Q000276:immunology* / Q000502:physiology
chemical_list: D005680:gamma-Aminobutyric Acid