[Interferons in the treatment of solid tumors. A general review].
A potential activity of interferons in the treatment of solid tumors has been suggested by in vitro experiments and, more recently, by phase I trials. Phase II trials have demonstrated a possible antitumoral activity in treating some solid tumors: malignant melanoma, renal cell carcinoma, ovarian adenocarcinoma, carcinoid tumor, superficial bladder cancer. Further trials are necessary to establish the precise role of interferons in treating solid tumors, when administered alone or in combination.
Dorval
T
T
Service de médecine oncologique, Institut Curie, Paris, France.
Pouillart
P
P
D002276:Carcinoid Tumor / Q000628:therapy; D002453:Cell Cycle / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D005260:Female; D006801:Humans; D007372:Interferons / Q000494:pharmacology / Q000627:therapeutic use*; D007680:Kidney Neoplasms / Q000628:therapy; D008297:Male; D008545:Melanoma / Q000556:secondary / Q000628:therapy; D009369:Neoplasms / Q000628:therapy*; D010051:Ovarian Neoplasms / Q000628:therapy; D001749:Urinary Bladder Neoplasms / Q000628:therapy
D007372:Interferons
Interférons dans le traitement des tumeurs solides. Revue générale.