Substance P-like immunoreactivity in sympathetic ganglion from toad.
Substance P-like immunoreactivity cellular in toad sympathetic ganglia was studied in normal and capsaicin-treated ganglia. In the eighth sympathetic ganglion substance P-like immunoreactive are found in mast cells and SIF cells. The effect of substance P (0.001-0.003 mM) caused increase of compound action potential during tetanical stimulation (50 Hz by 40 sec.) and post-tetanic potentiation (0.1 Hz). Our results show that substance P facilitates synaptic transmission in the sympathetic ganglia from Caudiverbera caudiverbera.
Montoya
G A
GA
Villena
F
F
Jofre
A
A
Pezo
A A
AA
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D001001:Anura; D002211:Capsaicin / Q000494:pharmacology; D005728:Ganglia, Sympathetic / Q000032:analysis* / Q000187:drug effects; D007150:Immunohistochemistry; D008407:Mast Cells / Q000032:analysis*; D013373:Substance P / Q000032:analysis* / Q000276:immunology / Q000494:pharmacology; D009435:Synaptic Transmission
D013373:Substance P; D002211:Capsaicin