[Preliminary results of an open study on the effects of DEAE-dextran on various lipid metabolism parameters in dyslipidemic subjects].
The authors report the results of a study of 1963 patients treated with daily doses of 2 g DEAE-dextran. This was an open trial intended to evaluate the evolution of several biohumoral parameters under treatment for dyslipidemias. Statistically significant results were obtained for cholesterol blood level, triglycerides and body weight, as well as a favorable trend for HDL-cholesterol. Side effects or untoward reactions to DEAE-dextran were not observed.
Graziani
P
P
Leproux
G B
GB
Gavelli
M S
MS
Vitaliano
E
E
Serra
T
T
Santini
G
G
D000368:Aged; D000369:Aged, 80 and over; D001835:Body Weight / Q000187:drug effects; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D003637:DEAE-Dextran / Q000627:therapeutic use*; D003911:Dextrans / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000150:complications / Q000188:drug therapy; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D003911:Dextrans; D000960:Hypolipidemic Agents; D014280:Triglycerides; D003637:DEAE-Dextran; D002784:Cholesterol
Prime osservazioni di uno studio aperto sugli effetti del DEAE-destrano su alcuni parametri lipometabolici di soggetti dislipidemici.