Increased cyclosporine uptake by cells pretreated with FK506 and evidence for binding of both drugs to a common intracellular protein.
Sanghvi
A
A
Department of Pathology, University of Pittsburgh School of Medicine, Pennsylvania.
Warty
V S
VS
Diven
W F
WF
Todo
S
S
Starzl
T
T
D002478:Cells, Cultured; D003524:Cyclosporins / Q000378:metabolism*; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007700:Kinetics; D008214:Lymphocytes / Q000378:metabolism*; D011485:Protein Binding; D011725:Pyridines / Q000494:pharmacology*; D011971:Receptors, Immunologic / Q000378:metabolism*; D016559:Tacrolimus
D003524:Cyclosporins; D007166:Immunosuppressive Agents; D011725:Pyridines; D011971:Receptors, Immunologic; C028752:cyclosporin receptor; D016559:Tacrolimus