Electron microscopic detection of Whipple's bacillus in sarcoidlike periodic acid-Schiff-negative granulomas.
We describe a patient with Whipple's disease without apparent intestinal involvement at initial presentation. Electron microscopy demonstrated the typical bacilli in PAS-negative lymph node and muscle biopsy specimens.
Spapen
H D
HD
Department of Internal Medicine, Vrije Universiteit Brussel, Belgium.
Segers
O
O
De Wit
N
N
Goossens
A
A
Buydens
P
P
Dierckx
R
R
Somers
G
G
D001706:Biopsy; D004378:Duodenal Diseases / Q000382:microbiology*; D004386:Duodenum / Q000473:pathology; D006099:Granuloma / Q000382:microbiology*; D006644:Histiocytes / Q000648:ultrastructure*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D010503:Periodic Acid-Schiff Reaction; D008061:Whipple Disease / Q000382:microbiology*