title: Discrimination of the determinant specificity of two competitive Semliki Forest virus neutralizing monoclonal antibodies by anti-idiotypic antibodies.
abstract: The two highly competitive, monoclonal antibodies (MAs), UM 5.1 and UM 8.1, recognize on the E2 glycoprotein of Semliki Forest virus different determinants as indicated by the absence of cross-reactive anti-idiotypic antibodies in rabbit immune sera induced against these highly neutralizing MAs.
authors: Laboratorium voor Microbiologie, Rijksuniversiteit Utrecht, The Netherlands.
authors: T A
authors: TA
authors: Oosterlaken
authors: C A
authors: CA
authors: Kraaijeveld
authors: A
authors: A
authors: Snijders
authors: M
authors: M
authors: Harmsen
authors: B J
authors: BJ
authors: Benaissa-Trouw
authors: H
authors: H
authors: Snippe
mesh_terms: D000818:Animals; D000888:Antibodies, Anti-Idiotypic; D000911:Antibodies, Monoclonal; D000918:Antibody Specificity; D001667:Binding, Competitive; D000939:Epitopes / Q000032:analysis*; D007130:Immunoglobulin Idiotypes / Q000276:immunology*; D007739:L Cells; D051379:Mice; D009500:Neutralization Tests; D012672:Semliki forest virus / Q000276:immunology*; D014764:Viral Proteins / Q000276:immunology*; D014776:Virus Cultivation
chemical_list: D000888:Antibodies, Anti-Idiotypic; D000911:Antibodies, Monoclonal; D000939:Epitopes; D007130:Immunoglobulin Idiotypes; D014764:Viral Proteins