[Scleromyxedema without paraproteinemia].
The identification of an abnormal paraproteinaemia has been considered as main criterium for the diagnosis of scleromyxedema. We report a case of scleromyxedema in a 51-year old man, without any immunochemical evidence of paraprotein. Our case is a clinical support to the independence of this disease from gammopathy, as underlined by other experimental and clinical data. Thus demonstration of paraprotein should not be considered as a fundamental criterion for the diagnosis of scleromyxedema.
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D001797:Blood Protein Electrophoresis; D005347:Fibroblasts / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009077:Mucins / Q000032:analysis; D010266:Paraproteins; D012871:Skin Diseases / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D013194:Staining and Labeling
D009077:Mucins; D010266:Paraproteins
Scleromixedema senza paraproteinemia.