[Experimental studies of the prevention of postoperative adhesions].
Female wistar rats were used for the testing of different substances to prevent postoperative intraabdominal adhesions. It could be demonstrated that the best results were obtained by dextran 70 with a concentration of 10%. Good effects were seen also by contrykal (aprotinin) and hylase (hyaluronidase). By the combination of dextran 70 30% with contrykal the spread of adhesions was very low but the effect was not significant better than with dextran 70 10% alone. For the prevention of intraabdominal adhesions operative techniques with minimal lesions are important too of the peritoneal epithelium.
Schwarz
J
J
Klinik für Gynäkologie und Geburtshilfe, Medizinischen Akademie Magdeburg.
Donat
H
H
D000818:Animals; D007611:Aprotinin / Q000008:administration & dosage; D002918:Chymotrypsin / Q000008:administration & dosage; D003911:Dextrans / Q000008:administration & dosage; D005260:Female; D005836:Genitalia, Female / Q000473:pathology / Q000601:surgery*; D006821:Hyaluronoglucosaminidase / Q000008:administration & dosage; D011183:Postoperative Complications / Q000473:pathology / Q000517:prevention & control*; D051381:Rats; D012965:Sodium Chloride / Q000008:administration & dosage; D000267:Tissue Adhesions
D003911:Dextrans; D012965:Sodium Chloride; D007611:Aprotinin; D006821:Hyaluronoglucosaminidase; D002918:Chymotrypsin
Experimentelle Untersuchungen zur Prävention postoperativer Adhäsionen.