Contact thermography for assessment of skin damage due to experimental irritants.
Irritant dermatitis after application of experimental irritants was studied by means of contact thermography. Sixteen healthy persons were patch-tested, using the following irritants: Sodium lauryl sulphate, benzalkonium chloride, nonanoic acid, hydrochloric acid, croton oil, sapo kalinus and sodium hydroxide. A main finding was that croton oil after 24 h caused a warm skin lesion, and sodium lauryl sulphate after 96 h caused a cold skin lesion. This study emphasizes the differences in the skin reactions to different irritants.
Agner
T
T
Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark.
Serup
J
J
D003436:Croton Oil / Q000009:adverse effects; D003877:Dermatitis, Contact / Q000209:etiology*; D006801:Humans; D007509:Irritants / Q000009:adverse effects*; D010328:Patch Tests / Q000379:methods; D012881:Skin Temperature / Q000187:drug effects; D012967:Sodium Dodecyl Sulfate / Q000009:adverse effects; D013817:Thermography / Q000379:methods*
D007509:Irritants; D012967:Sodium Dodecyl Sulfate; D003436:Croton Oil