Marrow grown in long-term culture can be used for autologous transplantation in the treatment of acute myeloid leukaemia.
Leukaemic cells can be selectively depleted in the conditions of long-term bone marrow culture (LTBMC). Use can be made of LTBMC to purge bone marrow of leukaemic cells in autologous bone marrow transplantation (ABMT).
Chang
J
J
Christie Hospital and Holt Radium Institute, Manchester, U.K.
Morgenstern
G R
GR
Testa
N G
NG
Dexter
T M
TM
D000293:Adolescent; D000328:Adult; D001854:Bone Marrow Cells; D016026:Bone Marrow Transplantation; D002478:Cells, Cultured; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000601:surgery*; D008297:Male; D014182:Transplantation, Autologous