title: Rhabdomyosarcoma presenting as a cutaneous nodule.
abstract: Two patients with rhabdomyosarcoma presented clinically with dermal nodules on the face. The first patient was a 12-month-old girl with a 2 X 3-cm-diameter red nodule on her left cheek that had begun as a small red papule when she was 3 months old and had progressively increased in size. The second patient was a 19-year-old girl who presented with an enlarging mass on her right cheek that had begun as a pea-sized nodule three months previously. In both cases, biopsies revealed a rhabdomyosarcoma in the underlying soft tissue with extension into the overlying dermis. Rhabdomyosarcoma presenting as a dermal nodule is rare. It usually presents as an asymptomatic papule without distinctive clinical features and therefore may result in delayed diagnosis unless a biopsy is performed.
authors: Department of Dermatology, University of Texas Medical Branch, Galveston.
authors: K
authors: K
authors: Wiss
authors: A R
authors: AR
authors: Solomon
authors: S S
authors: SS
authors: Raimer
authors: T E
authors: TE
authors: Lobe
authors: W
authors: W
authors: Gourley
authors: J T
authors: JT
authors: Headington
mesh_terms: D000328:Adult; D001706:Biopsy; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005153:Facial Neoplasms / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D007223:Infant; D008854:Microscopy, Electron; D011379:Prognosis; D012208:Rhabdomyosarcoma / Q000473:pathology* / Q000556:secondary / Q000628:therapy; D013194:Staining and Labeling