title: Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor.
abstract: Cloning and sequencing of the complementary DNA for platelet-derived endothelial cell growth factor indicates that it is a novel factor distinct from previously characterized proteins. The factor, a protein with a relative molecular mass of about 45,000, stimulates endothelial cell growth and chemotaxis in vitro and angiogenesis in vivo.
authors: Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.
authors: F
authors: F
authors: Ishikawa
authors: K
authors: K
authors: Miyazono
authors: U
authors: U
authors: Hellman
authors: H
authors: H
authors: Drexler
authors: C
authors: C
authors: Wernstedt
authors: K
authors: K
authors: Hagiwara
authors: K
authors: K
authors: Usuki
authors: F
authors: F
authors: Takaku
authors: W
authors: W
authors: Risau
authors: C H
authors: CH
authors: Heldin
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D015152:Blotting, Northern; D015139:Blotting, Southern; D002633:Chemotaxis; D002642:Chick Embryo; D003001:Cloning, Molecular; D004247:DNA; D051379:Mice; D008819:Mice, Nude; D008969:Molecular Sequence Data; D009389:Neovascularization, Pathologic; D010982:Platelet-Derived Growth Factor / Q000502:physiology*; D014407:Tumor Cells, Cultured
chemical_list: D010982:Platelet-Derived Growth Factor; D004247:DNA