title: [Complex radionuclide diagnosis of tumor lesions of the bones].
abstract: A complex examination of 320 patients with breast tumors of varying degree of advancement was carried out. Also, the data on examination of 20 cases of fibrous-cystic mastopathy and 40 healthy females were analysed. Similar studies were conducted in 20 cases of acute and chronic osteomyelitis, 14--tuberculosis of bones and joints, 63--rheumatoid arthritis and 36--Bekhterev's disease. Pyrphotech, Tc99m; pyrophosphate, Tc99m and diphosphonate Tc99m were used in carrying out scintigraphic examination. Parathyrin, prolactin, carcinoembryonic antigen (CEA), alpha-fetoprotein and ferritin were assayed in patients' blood serum. Tumor dissemination to bones was matched by a significant rise in CEA and prolactin levels. However, these parameters were normal in patients with non-tumor skeletal pathology. No significant rise in ferritin and alpha-fetoprotein were recorded in all patients. The specificity of the said complex examination, including osteoscintigraphy and blood plasma parathyrin assays in breast cancer patients, was 79%.
authors: I S
authors: IS
authors: Kolpakov
authors: V N
authors: VN
authors: Korsunskiĭ
authors: A Z
authors: AZ
authors: Naumenko
authors: V P
authors: VP
authors: Lapshin
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D001943:Breast Neoplasms; D002272:Carcinoembryonic Antigen / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D005293:Ferritins / Q000097:blood; D006801:Humans; D010281:Parathyroid Hormone / Q000097:blood; D011388:Prolactin / Q000097:blood; D011859:Radiography; D011877:Radionuclide Imaging; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D002272:Carcinoembryonic Antigen; D010281:Parathyroid Hormone; D000509:alpha-Fetoproteins; D011388:Prolactin; D005293:Ferritins
vernacular_title: Kompleksnaia radionuklidnaia diagnostika opukholevykh porazheniĭ skeleta.