title: The peptidergic innervation of the developing mesenteric vascular bed in the rat.
abstract: We have followed the development of perivascular nerve fibres using antisera to substance P, calcitonin gene related peptide, neuropeptide Y and vasoactive intestinal polypeptide in the mesenteric vascular bed of developing Sprague-Dawley rats. The pattern and density of innervation appeared to be determined by one week of age. The pattern of innervation by SP- and CGRP-positive fibres was similar. The pattern of innervation by neuropeptide Y-containing fibres was distinct from that of SP and CGRP. The VIP-positive fibre plexus was sparse and irregular compared with the others examined. The density of innervation by all fibre types was highest in the jejunal arteries.
authors: Faculty of Medicine, Memorial University of Newfoundland, St John's, Canada.
authors: T M
authors: TM
authors: Scott
authors: J
authors: J
authors: Robinson
authors: J
authors: J
authors: Foote
mesh_terms: D000818:Animals; D015740:Calcitonin Gene-Related Peptide / Q000378:metabolism; D008638:Mesenteric Arteries / Q000254:growth & development / Q000294:innervation*; D008642:Mesenteric Veins / Q000254:growth & development / Q000294:innervation*; D009478:Neuropeptide Y / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013373:Substance P / Q000378:metabolism; D014660:Vasoactive Intestinal Peptide / Q000378:metabolism
chemical_list: D009478:Neuropeptide Y; D013373:Substance P; D014660:Vasoactive Intestinal Peptide; D015740:Calcitonin Gene-Related Peptide