title: Optic disc neovascularization in dominant exudative vitreoretinopathy.
abstract: Dominant exudative vitreoretinopathy (DEVR) is inherited retinal vascular disorder which is characterized by peripheral retinal neovascularization, tractional retinal detachment, subretinal, exudation, and vitreous fibrosis. A milder form of involvement characterized by capillary nonperfusion and straightening of the retinal vessels may be present in asymptomatic individuals. We describe a 15-year-old patient who presented with optic disc neovascularization, a finding not previously reported in association with DEVR. Angiographic evidence of DEVR in successive generations confirmed the diagnosis. The findings in mild and advanced DEVR are reviewed, and the pathogenesis of the capillary nonperfusion is discussed.
authors: Moorfields Eye Hospital, London, England.
authors: M J
authors: MJ
authors: Barondes
authors: A M
authors: AM
authors: Hamilton
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic; D009898:Optic Disk / Q000098:blood supply*; D012164:Retinal Diseases / Q000235:genetics / Q000473:pathology*; D012171:Retinal Vessels / Q000473:pathology*