Identical forms of the CD2 antigen expressed by mouse T and B lymphocytes.
A monoclonal antibody (12-15) reactive with the mouse CD2 was used to study the expression of the antigen in different lymphoid cell subsets. By two-color immunofluorescence using B or T cell-specific reagents and cell sorting in combination with biochemical analysis we provide evidence that the CD2 antigen is present on mouse B and T cells. The antigen is expressed by both subsets at similar density and appears to be biochemically indistinguishable.
Altevogt
P
P
Institut für Immunologie und Genetik, Deutsches Krebsforschungszentrum, Heidelberg, FRG.
Michaelis
M
M
Kyewski
B
B
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D000943:Antigens, Differentiation / Q000276:immunology; D000945:Antigens, Differentiation, T-Lymphocyte / Q000276:immunology*; D001402:B-Lymphocytes / Q000276:immunology*; D015152:Blotting, Northern; D018801:CD2 Antigens; D000939:Epitopes; D005434:Flow Cytometry; D005455:Fluorescent Antibody Technique; D051379:Mice; D011233:Precipitin Tests; D011961:Receptors, Fc / Q000276:immunology; D017452:Receptors, IgG; D011971:Receptors, Immunologic / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
D000911:Antibodies, Monoclonal; D000943:Antigens, Differentiation; D000945:Antigens, Differentiation, T-Lymphocyte; D018801:CD2 Antigens; D000939:Epitopes; D011961:Receptors, Fc; D017452:Receptors, IgG; D011971:Receptors, Immunologic