[The action of gramicidin S on the ionic permeability of bilayer lipid membranes].
The effect of cyclic decapeptide of gramicidin S on electrical conductivity of bilayer lipid membranes has been studied. The integral conductivity of bilayer has been shown to increase with the growth of antibiotic concentration. The integral conductivity increase occurs as series of conductivity discrete leaps, differing in amplitude from fluctuations of conductivity caused by linear gramicidins. In the series of selectivity of bilayer membranes for cations of alkaline metals the rubidium ion is before the cesium ion. This is the only difference between this series and the series of relative ionic mobility series of cations of alkaline metals in water solutions.
Korolev
P N
PN
Bulgakova
V G
VG
Polin
A N
AN
Korolev
N P
NP
Mil'gram
V D
VD
D002463:Cell Membrane Permeability / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D004553:Electric Conductivity; D006096:Gramicidin / Q000494:pharmacology*; D066298:In Vitro Techniques; D008051:Lipid Bilayers / Q000494:pharmacology*; D008563:Membrane Lipids / Q000494:pharmacology*; D008670:Metals / Q000494:pharmacology
D008051:Lipid Bilayers; D008563:Membrane Lipids; D008670:Metals; D006096:Gramicidin
Deĭstvie gramitsidina S na ionnuiu pronitsaemost' bisloĭnykh lipidnykh membran.