An erythroid-specific DNA binding factor mediates increased gamma-globin expression in hereditary persistence of fetal hemoglobin (HPFH).
Martin
D I
DI
Department of Hematology/Oncology, Children's Hospital, Boston, Massachusetts.
Orkin
S H
SH
D001483:Base Sequence; D004268:DNA-Binding Proteins / Q000302:isolation & purification / Q000378:metabolism*; D015672:Erythroid Precursor Cells / Q000378:metabolism; D005319:Fetal Hemoglobin / Q000235:genetics; D005914:Globins / Q000096:biosynthesis / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D009928:Organ Specificity; D011401:Promoter Regions, Genetic; D012045:Regulatory Sequences, Nucleic Acid; D013789:Thalassemia / Q000235:genetics*; D014157:Transcription Factors / Q000302:isolation & purification / Q000378:metabolism*
D004268:DNA-Binding Proteins; D014157:Transcription Factors; D005914:Globins; D005319:Fetal Hemoglobin