Photodynamic therapy in gynecologic malignancies.
Twenty-one patients with recurrent gynecologic malignancies were treated with photodynamic therapy using Photofrin II and argon dye laser. Seven of twenty-one patients with cutaneous lesions treated palliatively had a complete response and four of eleven patients with cervical and vaginal recurrences had an objective response to phototherapy. Two of the patients with complete response continued to be free of disease after 28 and 36 months of follow-up.
Lele
S B
SB
Department of Gynecologic Oncology, Roswell Park Memorial Institute, Buffalo, New York 14263.
Piver
M S
MS
Mang
T S
TS
Dougherty
T J
TJ
Tomczak
M J
MJ
D017323:Dihematoporphyrin Ether; D004341:Drug Evaluation; D005260:Female; D005500:Follow-Up Studies; D005833:Genital Neoplasms, Female / Q000188:drug therapy*; D006415:Hematoporphyrins / Q000627:therapeutic use; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy; D010166:Palliative Care; D010778:Photochemotherapy / Q000009:adverse effects
D006415:Hematoporphyrins; D017323:Dihematoporphyrin Ether