[Cystitis in 8 patients treated with tranilast].
We encountered 8 cases of cystitis probably caused by Tranilast. Bladder biopsy performed on 6 of the 8 cases revealed eosinophilic cystitis in 3 cases. In the lymphocyte stimulation test using Tranilast as an antigen, a positive and false positive reaction was seen in one case each. This disease seemed to occur as a result of allergy of the bladder specific to Tranilast.
Kuwabara
T
T
Department of Urology, Mito Red Cross Hospital.
Kase
T
T
Kuroda
K
K
Suzuki
R
R
Ando
K
K
D000328:Adult; D000368:Aged; D001249:Asthma / Q000188:drug therapy; D003556:Cystitis / Q000139:chemically induced* / Q000473:pathology; D004802:Eosinophilia / Q000139:chemically induced / Q000473:pathology; D005260:Female; D006801:Humans; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D062367:ortho-Aminobenzoates / Q000009:adverse effects* / Q000494:pharmacology
D062367:ortho-Aminobenzoates; C012293:tranilast