title: Plasma exchange for removal of anti-A and anti-B group antibodies in AB0 major-incompatible bone marrow transplantation.
abstract: Between 1980-1986 seven patients underwent AB0-major incompatible bone marrow transplantation. Incompatible anti-A and anti-B antibodies could be decreased by the plasma exchange from titers 8-256 down to 0-8. Our practice combined with additional depletion of erythrocytes from marrow allowed to transplant all patients successfully, however, one patient demonstrated an acute haemolytic reaction during infusion of marrow. Plasma exchange was fairly well tolerated, however, 4 patients developed slight urticarial reactions. Both thrombocytopenic patients overcompensated the platelet loss caused by the exchange.
authors: Department of Internal Medicine, Karl Marx University, Leipzig, G.D.R.
authors: B
authors: B
authors: Haustein
authors: H
authors: H
authors: Achenbach
authors: A
authors: A
authors: Weissflog
authors: M
authors: M
authors: Kubel
mesh_terms: D000017:ABO Blood-Group System / Q000276:immunology*; D000328:Adult; D000906:Antibodies / Q000032:analysis; D001787:Blood Group Incompatibility; D016026:Bone Marrow Transplantation / Q000276:immunology*; D006801:Humans; D008297:Male; D010951:Plasma Exchange
chemical_list: D000017:ABO Blood-Group System; D000906:Antibodies