Measurement of monoamines and monoamine metabolites in various brain regions of six shark species.
1. The concentrations of six monoamines or monoamine metabolites were measured in six brain regions of six shark species using high performance liquid chromatography with electrochemical detection. 2. Serotonin concentrations were greatest in the hypothalamus and tegmentum, intermediate in the midline ridge formation, spinal cord and forebrain, and lowest in the cerebellum in all species. 3. Specie differences in dopamien concentration were significant only in the forebrain; species differences in the levels of the norepinephrine, epinephrine and 5-hydroxyindoleacetic acid were significant in most brain regions, including the midline ridge formation. 4. Differences and similarities to the mammalian pattern of monoamine distribution in the brain are discussed.
Howard
S B
SB
Department Biological Sciences, Rutgers University, Piscataway, NJ 08855-1059.
MacDonnell
M F
MF
Auerbach
S B
SB
D000818:Animals; D015306:Biogenic Monoamines / Q000378:metabolism*; D001921:Brain / Q000378:metabolism*; D002851:Chromatography, High Pressure Liquid; D004285:Dogs; D004298:Dopamine / Q000378:metabolism; D004837:Epinephrine / Q000378:metabolism; D006897:Hydroxyindoleacetic Acid / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism; D051381:Rats; D012701:Serotonin / Q000378:metabolism; D012754:Sharks / Q000378:metabolism*; D013045:Species Specificity
D015306:Biogenic Monoamines; D012701:Serotonin; D006897:Hydroxyindoleacetic Acid; D004298:Dopamine; D009638:Norepinephrine; D004837:Epinephrine