Alteration of renal blood flow during sequential embolization of the canine kidney.
Experimental embolization of the renal artery with cross-linked dextran (CLD) microspheres was performed in 6 dogs. The blood flow was monitored by electromagnetic flow meter (EM) in 3 dogs and by video dilution technique (VDT), adapted to an angiographic digital subtraction system, in a second group of 3 dogs. Retrograde flow in the embolized renal artery was detected by 99Tcm microspheres. Sequential emboli produce a predictable and equal flow response with both measuring techniques. Thus, the less invasive VDT can be used in the clinical setting to optimize and control embolization procedures. This type of flow monitoring has great potential in alerting the angiographer when approaching the risk level for retrograde flow.
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D P
DP
Department of Diagnostic Radiology, University of California Davis Medical Center, Sacramento 95817.
Lantz
B M
BM
Swanson
M
M
Tesluk
H
H
D000818:Animals; D003911:Dextrans / Q000627:therapeutic use; D004285:Dogs; D055590:Electromagnetic Phenomena; D004621:Embolization, Therapeutic; D007201:Indicator Dilution Techniques; D012077:Renal Artery; D012079:Renal Circulation; D012212:Rheology; D013668:Technetium Tc 99m Aggregated Albumin; D014741:Video Recording
D003911:Dextrans; D013668:Technetium Tc 99m Aggregated Albumin; C025614:sephadex