Liver transplantation: an unfinished product.
Liver transplantation has become an extraordinarily valuable and useful operation, but one that is not perfect and that has not been exploited to anything like its full potential. Better immunosuppression may become available soon as exemplified by developments with the Japanese drug, FK506. Improved preservation with the UW solution is already here. With these advantages, liver transplantation is certain to become far more widely used than at any time in the past. Examples were cited of innovative approaches using liver transplantation for the treatment of hepatic malignancies.
Starzl
T E
TE
Department of Surgery, University of Pittsburgh Health Center, Pennsylvania.
Todo
S
S
Tzakis
A G
AG
Gordon
R D
RD
Makowka
L
L
Stieber
A
A
Podesta
L
L
Yanaga
K
K
Concepcion
W
W
Iwatsuki
S
S
D000818:Animals; D001379:Azathioprine / Q000627:therapeutic use; D003524:Cyclosporins / Q000627:therapeutic use; D006085:Graft Survival; D006509:Hepatitis B / Q000517:prevention & control; D006801:Humans; D007165:Immunosuppression Therapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016031:Liver Transplantation; D011725:Pyridines / Q000627:therapeutic use; D016559:Tacrolimus; D014021:Tissue Preservation
D003524:Cyclosporins; D007166:Immunosuppressive Agents; D011725:Pyridines; D001379:Azathioprine; D016559:Tacrolimus