title: Unusual promoter-independent transcription reactions with bacteriophage RNA polymerases.
abstract: Efficient transcription reactions of DNA-dependent RNA polymerases require the presence of a specific promoter sequence. This report shows that in the absence of their cognate promoter, two bacteriophage RNA polymerases are capable of performing unusual transcription reactions: (i) the DNA template serves also as a primer for RNA synthesis and this leads to hybrid DNA/RNA molecules, (ii) if the DNA template forms a hairpin structure, the linear DNA can be transcribed via the 'rolling circle' mechanism.
authors: Institute for General Microbiology, Kiel, FRG.
authors: G
authors: G
authors: Krupp
mesh_terms: D005075:Biological Evolution; D003090:Coliphages / Q000201:enzymology*; D012321:DNA-Directed RNA Polymerases / Q000502:physiology*; D009838:Oligodeoxyribonucleotides / Q000378:metabolism; D011401:Promoter Regions, Genetic; D012313:RNA / Q000096:biosynthesis*; D012045:Regulatory Sequences, Nucleic Acid; D013698:Templates, Genetic; D014158:Transcription, Genetic
chemical_list: D009838:Oligodeoxyribonucleotides; D012313:RNA; D012321:DNA-Directed RNA Polymerases