title: [The localization of the components of the extracellular matrix and cytoskeleton in myocardial biopsies in alcoholic cardiomyopathy].
abstract: Distribution of I, III, IV and V-type collagen, fibronectin, vimentin, filamin, and desmin in myocardial biopsy specimens of 8 patients with alcoholic cardiomyopathy was studied by indirect immunofluorescence. It is found that all types of collagen and fibronectin participate in formation of diffuse cardiosclerosis while small cardiosclerosis is formed by interstitial types of collagen and to a lower extent of fibronectin. Filamin and desmin distribution in cardiomyocytes proves deformation and destruction of Z-lines and intercalated discs.
authors: V S
authors: VS
authors: Rukosuev
authors: A K
authors: AK
authors: Nanaev
authors: A N
authors: AN
authors: Samko
authors: V P
authors: VP
authors: Shirinskiĭ
authors: T A
authors: TA
authors: Batyraliev
mesh_terms: D000911:Antibodies, Monoclonal; D001706:Biopsy; D002310:Cardiomyopathy, Alcoholic / Q000473:pathology*; D003599:Cytoskeleton / Q000648:ultrastructure*; D005109:Extracellular Matrix / Q000648:ultrastructure*; D005455:Fluorescent Antibody Technique; D006352:Heart Ventricles / Q000648:ultrastructure; D006801:Humans; D009206:Myocardium / Q000648:ultrastructure*; D013194:Staining and Labeling / Q000379:methods
chemical_list: D000911:Antibodies, Monoclonal
vernacular_title: Lokalizatsiia nekotorykh komponentov vnekletochnogo matriksa i tsitoskeleta v miokarde bioptatov pri alkogol'noĭ kardiomiopatii.