title: Common surface epitope of Bartonella bacilliformis and Chlamydia psittaci.
abstract: A serosurvey revealed intense cross-reactivity between Bartonella bacilliformis and Chlamydia psittaci. One of the cross-reacting Bartonella antigens was identified as lipopolysaccharide which reacted with Bartonella as well as with Chlamydia serum antibodies. A monoclonal Bartonella antibody bound to Bartonella lipopolysaccharide as well as to the surfaces of Bartonella bacilliformis and Chlamydia psittaci. It was thus demonstrated that Chlamydia psittaci carries a surface epitope identical to an epitope of Bartonella lipopolysaccharide. The lipopolysaccharide was preliminarily characterized by polyacrylamide gel electrophoresis and by a lectin-binding assay. The lipopolysaccharides of Bartonella bacilliformis and Chlamydia psittaci are not identical.
authors: Bernhard-Nocht-Institut für Tropenmedizin, Hamburg, Federal Republic of Germany.
authors: J
authors: J
authors: Knobloch
authors: R
authors: R
authors: Bialek
authors: G
authors: G
authors: Müller
authors: P
authors: P
authors: Asmus
mesh_terms: D000907:Antibodies, Bacterial / Q000276:immunology; D000942:Antigens, Bacterial / Q000032:analysis / Q000276:immunology*; D000954:Antigens, Surface / Q000032:analysis / Q000276:immunology; D001473:Bartonella / Q000276:immunology* / Q000648:ultrastructure; D002691:Chlamydophila psittaci / Q000276:immunology* / Q000648:ultrastructure; D003429:Cross Reactions; D004591:Electrophoresis, Polyacrylamide Gel; D004797:Enzyme-Linked Immunosorbent Assay; D000939:Epitopes / Q000032:analysis / Q000276:immunology; D006801:Humans; D007106:Immune Sera / Q000276:immunology; D007150:Immunohistochemistry; D037102:Lectins / Q000378:metabolism; D008070:Lipopolysaccharides / Q000032:analysis / Q000276:immunology; D008854:Microscopy, Electron
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D000954:Antigens, Surface; D000939:Epitopes; D007106:Immune Sera; D037102:Lectins; D008070:Lipopolysaccharides