Equine interferons following exposure to equid herpesvirus-1 or -4.
When 23 ponies were infected with equid herpesvirus-1 or -4 (EHV-1 or EHV-4), nasal shedding of interferon (IFN) correlated closely with the duration of viral excretion. Equine interferon (EqIFN) was detected in the serum only from animals infected with the EHV-1 virus, and here high levels correlated with clinical symptoms of locomotor disorder and indicated a poor prognosis. Low levels of IFN were detected in explanted mononuclear cells from ponies infected with either virus.
Edington
N
N
Department of Veterinary Pathology, Royal Veterinary College, University of London.
Bridges
C G
CG
Griffiths
L
L
D000818:Animals; D005260:Female; D006566:Herpesviridae Infections / Q000276:immunology / Q000662:veterinary*; D004861:Herpesvirus 1, Equid; D006734:Horse Diseases / Q000276:immunology* / Q000382:microbiology; D006736:Horses; D007372:Interferons / Q000096:biosynthesis*; D014766:Viremia / Q000276:immunology / Q000662:veterinary*
D007372:Interferons