[Lung metastases of prostatic cancer vanished by early combined hormonal and chemotherapy: report of a case].
A 69-year-old man initially came to our hospital with the chief complaint of dysuria and hematuria. On rectal examination, the prostate gland was found to be grossly enlarged and rock hard in consistency. Abnormal laboratory data included: lactate dehydrogenase, alkaline phosphatase, acid phosphatase and prostatic acid phosphatase. Chest X-ray revealed multiple nodular lesions in both lung fields. Pathologic findings of the prostate needle biopsy revealed moderately well differentiated adenocarcinoma. Early combined hormonal and chemotherapy (adriamycin, TGF, methotrexate, bleomycin) was performed. After two courses of this regimen, the pulmonary lesions vanished completely. In addition, partial disappearance of osteoblastic lesions on bone scans was recognized.
Sakamoto
S
S
Department of Urology, Saitama Medical School.
Kusuyama
H
H
Numa
H
H
Okada
K
K
D000230:Adenocarcinoma / Q000556:secondary* / Q000601:surgery / Q000628:therapy; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004317:Doxorubicin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D004961:Estramustine / Q000008:administration & dosage; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary* / Q000601:surgery / Q000628:therapy; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D009919:Orchiectomy; D011471:Prostatic Neoplasms; D011509:Proteoglycans / Q000008:administration & dosage; D005641:Tegafur / Q000008:administration & dosage; D014498:Uracil / Q000008:administration & dosage
D011509:Proteoglycans; D001761:Bleomycin; D005641:Tegafur; D004961:Estramustine; C010770:polysaccharide-K; D014498:Uracil; D004317:Doxorubicin; D008727:Methotrexate