title: The expression of genes coding for positive acute-phase proteins in the reproductive tract of the female rat. High levels of ceruloplasmin mRNA in the uterus.
abstract: High levels of ceruloplasmin mRNA were measured in the uterus of both pregnant and non-pregnant rats. No mRNA for alpha 2-macroglobulin and alpha 1-acid glycoprotein could be detected in the uterus in contrast to the high levels of those two mRNAs found in the decidua in the mid-gestation period. Synthesis of plasma proteins with a protective function in the decidua or uterus may be important in maintaining homeostasis at different stages of reproduction. In addition, ceruloplasmin synthesis by the uterus may be part of a system transporting copper to the fetus.
authors: Russell Grimwade School of Biochemistry, University of Melbourne, Parkville, VIC, Australia.
authors: T
authors: T
authors: Thomas
authors: G
authors: G
authors: Schreiber
mesh_terms: D000209:Acute-Phase Proteins / Q000235:genetics* / Q000378:metabolism; D000818:Animals; D002570:Ceruloplasmin / Q000235:genetics* / Q000378:metabolism / Q000502:physiology; D003656:Decidua / Q000378:metabolism*; D005260:Female; D005786:Gene Expression Regulation; D006706:Homeostasis; D009961:Orosomucoid / Q000235:genetics; D010920:Placenta / Q000378:metabolism; D011247:Pregnancy; D012333:RNA, Messenger / Q000378:metabolism*; D051381:Rats; D014168:Transferrin / Q000235:genetics; D014599:Uterus / Q000378:metabolism*; D015017:Yolk Sac / Q000378:metabolism; D000511:alpha-Macroglobulins / Q000235:genetics
chemical_list: D000209:Acute-Phase Proteins; D009961:Orosomucoid; D012333:RNA, Messenger; D014168:Transferrin; D000511:alpha-Macroglobulins; D002570:Ceruloplasmin