[Thrombocyte-specific antigens/antibodies and their clinical importance].
This review updates our present state of knowledge with regard to platelet-specific alloantigens, i.e. Zwa/Zwb (PlAl/PlA2), Baka/Bakb, Koa/Kob, Yuka/Yukb (Penb/Pena), Bra/Brb, Nak, Sib, and summarizes relevant immunogenetical and biochemical data. The impact of corresponding platelet-specific antibodies in clinical conditions such as neonatal alloimmune thrombocytopenia, posttransfusion purpura, and the refractory state of platelet transfusions is reviewed with particular emphasis on our own case material.
Mueller-Echardt
C
C
Institut für Klinische Immunologie und Transfusionsmedizin, Justus-Liebig-Universität, Giessen, BRD.
Kiefel
V
V
Santoso
S
S
D001323:Autoantibodies / Q000032:analysis*; D001792:Blood Platelets / Q000276:immunology*; D001803:Blood Transfusion; D006801:Humans; D007519:Isoantigens / Q000276:immunology*; D017713:Platelet Transfusion; D013921:Thrombocytopenia / Q000276:immunology*
D001323:Autoantibodies; D007519:Isoantigens
Thrombozytenspezifische Antigene/Antikörper und ihre klinische Bedeutung.