Effects of fibrin sealant on the fixation of porous titanium and pyrolytic carbon implants.
The authors investigated the potential role the fibrin sealant system may portray in the fixation of osseous implants. The application of a layer of fibrin did not interfere with the fixation of osseous implants of either pyrolytic carbon or Biolite-coated porous titanium. A greater percentage of tissue ingrowth was observed in the porous titanium implants in the presence of the fibrin sealant system; however, no significant difference in the ultimate interfacial shear stress was observed.
Hetherington
V J
VJ
University of Osteopathic Medicine and Health Sciences, College of Podiatric Medicine and Surgery, Des Moines, Iowa.
Park
J B
JB
Park
S H
SH
Carnett
J A
JA
Patterson
B A
BA
Bratkiewicz
L
L
Kessler
D A
DA
D000818:Animals; D007611:Aprotinin / Q000494:pharmacology*; D002244:Carbon; D004285:Dogs; D004338:Drug Combinations / Q000494:pharmacology; D005176:Factor XIII / Q000494:pharmacology*; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen / Q000494:pharmacology*; D007595:Joint Prosthesis; D019736:Prostheses and Implants; D013917:Thrombin / Q000494:pharmacology*; D014014:Tissue Adhesives / Q000494:pharmacology*; D014025:Titanium
D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives; C009139:pyrolytic carbon; D002244:Carbon; D005340:Fibrinogen; D005176:Factor XIII; D007611:Aprotinin; D014025:Titanium; D013917:Thrombin