title: [Determination of thymidine phosphorylase in adenoma and cancer of the human prostate].
abstract: The presence of thymidine phosphorylase was observed in healthy, adenomatous and tumoral prostatic cells. In healthy and adenomatous tissues the enzyme activity was recovered as a single peak after ion exchange chromatography on DEAE-Sephadex gel. On the contrary, two forms of thymidine phosphorylase were found in prostatic cancers, one of them, with high activity appeared consequently as a characteristic feature of prostatic tumoral cells.
authors: Centre Régional de Recherche en Endocrinologie, Faculté de Médecine et Pharmacie, Rennes.
authors: S
authors: S
authors: Touffet
authors: S
authors: S
authors: Samperez
authors: P
authors: P
authors: Jouan
mesh_terms: D002852:Chromatography, Ion Exchange; D006801:Humans; D008297:Male; D010430:Pentosyltransferases / Q000032:analysis*; D011467:Prostate / Q000201:enzymology; D011470:Prostatic Hyperplasia / Q000201:enzymology*; D011471:Prostatic Neoplasms / Q000201:enzymology*; D013939:Thymidine Phosphorylase / Q000032:analysis* / Q000302:isolation & purification / Q000378:metabolism
chemical_list: D010430:Pentosyltransferases; D013939:Thymidine Phosphorylase
vernacular_title: Mise en évidence de la thymidine phosphorylase dans les adénomes et les cancers de la prostate humaine.