[The effect of ultrasound on the functional state of the nicotinic cholinoreceptors in mollusk neurons].
It was found that ultrasound (0.5 W/cm2, 2.64 MHz) produced a blocking effect on acetylcholine (ACh)-induced chloride current in Helix pomatia neurons. Atropine blocked the chloride channels opened by ACh and did not prevent from the blocking effect of ultrasound. Ultrasound became effectless after binding of ACh molecules to the recognizing centre of nicotinic acetylcholine receptors.
Diatlov
V A
VA
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D002463:Cell Membrane Permeability / Q000187:drug effects / Q000502:physiology; D066298:In Vitro Techniques; D007473:Ion Channels / Q000187:drug effects / Q000502:physiology; D008974:Mollusca / Q000187:drug effects / Q000502:physiology*; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D011978:Receptors, Nicotinic / Q000187:drug effects / Q000502:physiology*; D014465:Ultrasonics
D007473:Ion Channels; D011978:Receptors, Nicotinic; D001285:Atropine; D000109:Acetylcholine
Vliianie ul'trazvuka na funktsional'noe sostoianie nikotinovykh kholinoretseptorov neĭronov molliuska.