title: Origins of substance P- and calcitonin gene-related peptide-containing nerves in the internal carotid artery of rat.
abstract: An aggregation of substance P (SP)- and calcitonin gene-related peptide (CGRP)-containing nerve cells (internal carotid mini-ganglion) is described at the junction between the greater superficial petrosal nerve and the internal carotid nerve close to the internal carotid artery. A retrograde tracer dye technique demonstrates that this ganglion and the trigeminal and superior vagal ganglia supply the internal carotid artery with SP/CGRP fibers at, above and below this level, respectively. Implications of this finding for cranial painful syndromes in man are discussed.
authors: Department of Medical Cell Research, University of Lund, Sweden.
authors: J E
authors: JE
authors: Hardebo
authors: N
authors: N
authors: Suzuki
authors: C
authors: C
authors: Owman
mesh_terms: D000818:Animals; D001572:Benzofurans; D015740:Calcitonin Gene-Related Peptide; D002343:Carotid Artery, Internal / Q000294:innervation*; D005456:Fluorescent Dyes; D007150:Immunohistochemistry; D008297:Male; D009479:Neuropeptides / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains; D013373:Substance P / Q000032:analysis*; D014665:Vasodilator Agents / Q000032:analysis
chemical_list: D001572:Benzofurans; D005456:Fluorescent Dyes; D009479:Neuropeptides; D014665:Vasodilator Agents; D013373:Substance P; C038675:true blue; D015740:Calcitonin Gene-Related Peptide