Maternal serum AFP levels in the first trimester of pregnancy.
Maternal serum alphafetoprotein was assayed in 436 women presenting for termination of pregnancy at 6 to 12 weeks. The normal range for each week is presented. There was a progressive rise of AFP levels from week 7 onwards, but a clear separation from non-pregnant values was only apparent after 8 weeks. The definition of a 'low normal' range for the identification of cases at risk of Down's syndrome will probably only be possible at 11 weeks or later.
Olajide
F
F
Department of Obstetrics & Gynaecology, St. Bartholomew's Hospital Medical College, London, U.K.
Kitau
M J
MJ
Chard
T
T
D004314:Down Syndrome / Q000175:diagnosis; D005260:Female; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy / Q000097:blood*; D011261:Pregnancy Trimester, First; D011296:Prenatal Diagnosis; D012016:Reference Values; D000509:alpha-Fetoproteins / Q000032:analysis*
D000509:alpha-Fetoproteins