Radiation therapy alone and in combination with bleomycin and 5-fluorouracil in advanced carcinoma esophagus.
This presentation is a randomized prospective study of 74 patients of squamous cell carcinoma of esophagus divided into two groups. First group was treated with radical radiation alone and the other with radical radiation and combination of bleomycin and 5-FU. Analysis at the end of two years showed that the patients treated with addition of chemotherapy had an overall survival of 23 percent as compared to nine percent in the radiation alone group (P less than 0.05).
Hukku
S
S
Fernandes
P
P
Vasishta
S
S
Sharma
V K
VK
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D016032:Randomized Controlled Trials as Topic
D001761:Bleomycin; D005472:Fluorouracil