[Usefulness and limitations of hormonal monitoring of pregnancy with HPL and estriol in improving fetal prognosis and preventing neonatal neurologic deficiency].
This multidisciplinary research has been subdivided into two parts. The first examines prognosis of the foetus and its weight development in relation to changes in the hormonal curves of HPL and E3 carried out in a batch of 339 3rd term pregnancies. A very high incidence of small-for-date newborns (30-64%) was noted in mothers with low hormonal values and generally a more frequent onset of hypoxia in pregnancy and in labour. The second part assesses the neurological profile of children born to the same mothers examined in the first part up to the 4th year of life. A neurological deficiency of a different extent was evidenced in 33.3% of the children born to mothers with low hormonal values in pregnancy, especially among those born underweight. The neurological deficiency in the control sample was 7.84%.
Paci
S
S
Russo
G
G
Mure
G
G
Parisi
R
R
de Filippo
V
V
Correnti
R
R
Eliamo
A
A
Comis
B
B
Latagliata
C
C
Ventimiglia
E
E
D000293:Adolescent; D000328:Adult; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000209:etiology*; D004964:Estriol / Q000097:blood*; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology*; D005311:Fetal Hypoxia / Q000209:etiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010928:Placental Lactogen / Q000097:blood*; D011237:Predictive Value of Tests; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D011379:Prognosis
D010928:Placental Lactogen; D004964:Estriol
Utilità e limiti del monitoraggio ormonale della gravidanza con HPL ed estriolo nel miglioramento della prognosi fetale e nella prevenzione del deficit neurologico neonatale.