Neisseria meningitidis: heterogenicity in the outer membrane proteins released into the growth medium.
Eight strains of Neisseria meningitidis belonging to different serogroups were analysed for their virulence in mice and their release of outer membrane proteins into the medium during growth. All strains released proteins. No detectable lipopolysaccharide was observed. However, SDS-PAGE showed a heterogenicity in the protein number and profile among the different strains of N. meningitidis tested.
Jascolt
E
E
Biomedical Defence Section, Defence Research Establishment Suffield, Ralston, Alberta, Canada.
Siddiqui
S
S
Chaudhry
G R
GR
Bhatti
A R
AR
D000818:Animals; D001425:Bacterial Outer Membrane Proteins / Q000032:analysis / Q000145:classification*; D001789:Blood Group Antigens; D004591:Electrophoresis, Polyacrylamide Gel; D006023:Glycoproteins / Q000032:analysis; D008070:Lipopolysaccharides / Q000032:analysis; D051379:Mice; D008970:Molecular Weight; D009345:Neisseria meningitidis / Q000032:analysis* / Q000254:growth & development / Q000472:pathogenicity; D012834:Silver; D013194:Staining and Labeling; D014774:Virulence
D001425:Bacterial Outer Membrane Proteins; D001789:Blood Group Antigens; D006023:Glycoproteins; D008070:Lipopolysaccharides; D012834:Silver