Influence of beta-sitosterol on the fibrinolytic potential in rabbits.
Long-term treatment of rabbits with beta-sitosterol (40 mg/kg over 3 months) caused an increased fibrinolytic activity in blood, an increased fibrinolytic capacity and an enhanced plasminogen activator activity in tissue of lungs and kidneys. The 3-months lasting beta-sitosterol administration did not influence the content of plasminogen activator inhibitor, plasminogen, alpha 2-antiplasmin, antithrombin III and fibrinogen.
Hoffmann
A
A
Institute of Pharmacology and Toxicology, Medical Academy Erfurt, GDR.
Klöcking
H P
HP
D000818:Animals; D005260:Female; D005342:Fibrinolysis / Q000187:drug effects*; D007668:Kidney / Q000201:enzymology; D008026:Ligation; D008168:Lung / Q000201:enzymology; D008297:Male; D010960:Plasminogen Activators / Q000037:antagonists & inhibitors / Q000097:blood; D015849:Plasminogen Inactivators; D011817:Rabbits; D012855:Sitosterols / Q000494:pharmacology*; D013997:Time Factors
D015849:Plasminogen Inactivators; D012855:Sitosterols; C025473:gamma-sitosterol; D010960:Plasminogen Activators