title: Cloning and nucleotide sequence of placental hGH-V cDNA.
abstract: We have previously demonstrated the presence in human placenta and maternal serum of a GH variant, called human placental growth hormone (hPGH). We have also shown that the hGH-V gene is expressed at the placental level thus possibly coding for hPGH. The hGH-V cDNA has now been isolated from a lambda gt 11 human placenta cDNA library. Its sequence has been determined which firmly establishes the GH-V gene mode of splicing as well as the GH-V protein structure. Our data give final evidence of placental hGH-V gene expression and reinforce the hypothesis of identity between the hGH-V protein and hPGH.
authors: Endocrinologie Clinique et Expérimentale, Centre Hospitalier Universitaire, Liège.
authors: A
authors: A
authors: Igout
authors: M L
authors: ML
authors: Scippo
authors: F
authors: F
authors: Frankenne
authors: G
authors: G
authors: Hennen
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics*; D005260:Female; D013006:Growth Hormone / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy
chemical_list: D013006:Growth Hormone; D004247:DNA