[ICO-45 monoclonal antibodies to the new epitope of antigen CD38].
Monoclonal antibodies (MoAB) ICO-45 discovered the antigen with 45 kD molecular mass, expressed on the surface of 77% thymocytes, 68% monocytes, 95% granulocytes, 46% T-lymphocytes, 59% non-T-lymphocytes. MoAB ICO-45 blocked T-lymphocyte blast transformation and inhibited the respiratory burst of monocytes and granulocytes of the peripheral blood.
Baryshnikov
A Iu
AIu
Zabotina
T N
TN
Dubinkin
I V
IV
Korotkova
O V
OV
Shchvartsbergs
A M
AM
D000293:Adolescent; D000911:Antibodies, Monoclonal / Q000032:analysis* / Q000276:immunology; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D000939:Epitopes / Q000032:analysis / Q000276:immunology*; D005434:Flow Cytometry; D005455:Fluorescent Antibody Technique; D006801:Humans; D007223:Infant; D008213:Lymphocyte Activation; D008970:Molecular Weight; D011233:Precipitin Tests; D011863:Radioimmunoassay; D013601:T-Lymphocytes / Q000276:immunology
D000911:Antibodies, Monoclonal; D000945:Antigens, Differentiation, T-Lymphocyte; D000939:Epitopes
Monoklonal'nye antitela IKO-45 k novomu épitopu antigena CD38.