The clear-cell variant of uterine epithelioid leiomyoma. An immunohistologic and ultrastructural study.
A case of a rare uterine clear-cell epithelioid leiomyoma is presented, emphasizing immunohistologic and ultrastructural findings. The presence of actin, vimentin, desmin, muscle-specific antigen, and smooth-muscle-specific actin in tumor cells indicates a smooth-muscle origin, confirmed by electron microscopy. Numerous vacuolated mitochondria produced the cytoplasmic "clearing" on light microscopy.
Hyde
K E
KE
Department of Pathology, Wake Forest University, Bowman Gray School of Medicine, Winston-Salem, NC 27103.
Geisinger
K R
KR
Marshall
R B
RB
Jones
T L
TL
D000199:Actins / Q000378:metabolism; D000368:Aged; D003893:Desmin / Q000378:metabolism; D000939:Epitopes / Q000378:metabolism; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007889:Leiomyoma / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D009132:Muscles / Q000276:immunology; D014594:Uterine Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D014746:Vimentin / Q000378:metabolism
D000199:Actins; D003893:Desmin; D000939:Epitopes; D014746:Vimentin