[Clastogenicity effect of ruthenium red in vivo, in bone marrow cells in mice].
The ability of ruthenium red to induce chromosome aberrations in vivo in mammalian somatic cells has been evaluated by the micronucleus test on mouse bone marrow cells. Our results show that this compound, when administered i.p. at a sublethal level, can be considered as a weak clastogen.
Deknudt
G
G
Laboratoire de Génétique des Mammifères, Département de Radioprotection, Belgique.
van Hessche
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D
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects*; D001854:Bone Marrow Cells; D003520:Cyclophosphamide / Q000494:pharmacology; D005260:Female; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D015162:Micronucleus Tests; D009154:Mutation; D012428:Ruthenium / Q000494:pharmacology*; D012430:Ruthenium Red / Q000494:pharmacology*
D012430:Ruthenium Red; D012428:Ruthenium; D003520:Cyclophosphamide
Etude de l'effet clastogène du rouge de ruthénium in vivo, dans les cellules de moelle osseuse de la Souris.