title: Partial splenectomy for treatment of chronic idiopathic thrombocytopenia in childhood.
abstract: The aim of this paper was to demonstrate the efficiency of partial splenic resection in treatment of chronic idiopathic thrombocytepenie purpura (Werlhof-Disease). In all but one case remissions of thrombocyte counts over 100 Gpt/l could be achieved. Immunological studies demonstrate the existence of a suppressor-state after this operation, which could be responsible for success of this procedure. In contrast to general considerations the partial-splenectomized child must be considered as an immunological deficient organism for about 6 to 12 months. Restoration of immunological-means whole splenic functions-parameters is to expect always after this time.
authors: Department of Paediatric Surgery, Clinic and Ambulance for Surgery, GDR.
authors: U
authors: U
authors: Specht
authors: H
authors: H
authors: Mau
authors: H
authors: H
authors: Winter
authors: S
authors: S
authors: Jahn
authors: H
authors: H
authors: Volk
authors: W R
authors: WR
authors: Cario
mesh_terms: D000293:Adolescent; D002648:Child; D004912:Erythrocytes / Q000473:pathology; D005260:Female; D006801:Humans; D007159:Immunologic Tests; D008297:Male; D010976:Platelet Count; D011696:Purpura, Thrombocytopenic / Q000097:blood / Q000601:surgery*; D013156:Splenectomy