Dextran sulfate and pentosan polysulfate (HOE/BAY 946), potent anti-HIV-agents, inhibit protein kinase C.
Schiebler
W
W
Hoechst AG, Frankfurt, FRG.
Schmidt
C
C
Weber
P
P
D000818:Animals; D000998:Antiviral Agents; D001792:Blood Platelets / Q000378:metabolism; D001921:Brain / Q000201:enzymology; D002853:Chromatography, Liquid; D016264:Dextran Sulfate; D003911:Dextrans / Q000494:pharmacology*; D006678:HIV / Q000187:drug effects*; D008934:Mitogens; D010426:Pentosan Sulfuric Polyester / Q000494:pharmacology*; D010766:Phosphorylation; D011134:Polysaccharides / Q000494:pharmacology*; D011493:Protein Kinase C / Q000037:antagonists & inhibitors*; D051381:Rats; D012701:Serotonin / Q000378:metabolism; D013917:Thrombin / Q000378:metabolism
D000998:Antiviral Agents; D003911:Dextrans; D008934:Mitogens; D011134:Polysaccharides; D012701:Serotonin; D010426:Pentosan Sulfuric Polyester; D016264:Dextran Sulfate; D011493:Protein Kinase C; D013917:Thrombin