Effect of Cd2+ on growth of the cadmium-resistant and -sensitive Staphylococcus aureus.
The effect of Cd2+ on aerobic and anaerobic growth was studied in the Cd2+-resistant Staphylococcus aureus 17810R which harbours the cadA and cadB markers on a penicillinase plasmid pII17810. Also the effect of Cd2+ on growth of the plasmidless strain 17810S, sensitive to Cd2+ was investigated. The results indicate that under all growth conditions the Cd2+-resistant S. aureus 17810R is protected against Cd2+ toxicity up to 100 microM Cd2+ by the 2H+/Cd2+ antiporter, the product of the cadA gene. Energetics of growth of both strains under various conditions is also discussed.
Tynecka
Z
Z
Department of Pharmaceutical Microbiology, Medical Academy, Lublin, Poland.
Malm
A
A
Skwarek
T
T
D000693:Anaerobiosis; D002104:Cadmium / Q000494:pharmacology*; D003470:Culture Media; D004352:Drug Resistance, Microbial; D007476:Ionophores / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development*
D003470:Culture Media; D007476:Ionophores; D002104:Cadmium