title: PRPP and purine nucleotide metabolism in human lymphoblasts with both PRPP synthetase superactivity and HGPRT deficiency.
authors: Department of Medicine, University of Chicago, Illinois.
authors: M A
authors: MA
authors: Becker
authors: M
authors: M
authors: Kim
authors: K
authors: K
authors: Husain
mesh_terms: D001402:B-Lymphocytes / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D006801:Humans; D007041:Hypoxanthine Phosphoribosyltransferase / Q000172:deficiency*; D008778:Methylthioinosine / Q000494:pharmacology; D010428:Pentosephosphates / Q000378:metabolism*; D010754:Phosphoribosyl Pyrophosphate / Q000378:metabolism*; D010770:Phosphotransferases / Q000378:metabolism*; D011685:Purine Nucleotides / Q000378:metabolism*; D011687:Purines / Q000378:metabolism*; D012268:Ribose-Phosphate Pyrophosphokinase / Q000378:metabolism*; D013866:Thioguanine / Q000494:pharmacology
chemical_list: D010428:Pentosephosphates; D011685:Purine Nucleotides; D011687:Purines; D008778:Methylthioinosine; D010754:Phosphoribosyl Pyrophosphate; D007041:Hypoxanthine Phosphoribosyltransferase; D010770:Phosphotransferases; D012268:Ribose-Phosphate Pyrophosphokinase; D013866:Thioguanine