The effect of iloprost on the rabbit eye.
Some prostaglandins, topically applied, are known to lower intraocular pressure; a few have been shown to increase facility of outflow. Iloprost (ZK36374), a stable PGI2 analog, was tested in rabbits for effect on intraocular pressure and facility, but was found totally inactive on either.
Moses
R A
RA
Department of Ophthalmology, Washington University School of Medicine, St. Louis, Missouri.
Schmoll
D W
DW
Dihenia
B
B
D000287:Administration, Topical; D000818:Animals; D011464:Epoprostenol / Q000008:administration & dosage / Q000494:pharmacology*; D016285:Iloprost; D007429:Intraocular Pressure / Q000187:drug effects*; D011817:Rabbits
D011464:Epoprostenol; D016285:Iloprost