title: Results of total correction of tetralogy of Fallot performed in adults.
abstract: Today, total correction of tetralogy of Fallot is rarely performed in adults. In a 10-year period, 40 patients aged 20 to 67 years underwent intracardiac repair in our institution. Twenty-eight of them had had a palliative procedure 11 to 30 years earlier. Preoperatively, 23 patients were in New York Heart Association (NYHA) Functional Class II, 14 were in Class III, and 3 were in Class IV. Operative mortality was 2.5% (1/40). Follow-up ranged from 1 year to 11 years (average, 3 years). One patient died of a noncardiac cause 4 years after operation. Residual cardiac defects were observed in 4 patients. Postoperatively, 30 patients were in NYHA Functional Class I, 8 were in Class II, and 1 was in Class III. Major ventricular arrhythmias were recorded in 7 (35%) of 20 patients. Radionuclide angiography demonstrated impaired right ventricular function in 8 patients. Left ventricular impairment was present in 2. Total correction of tetralogy of Fallot can be performed safely in adults with low mortality and good functional improvement. The incidence of residual cardiac defects is low. The long-term importance of impaired ventricular function and arrhythmias remains to be ascertained.
authors: Istituto di Medicina e Chirurgia Cardiovascolare, Università di Torino, Italy.
authors: P
authors: P
authors: Presbitero
authors: D
authors: D
authors: Demarie
authors: E
authors: E
authors: Aruta
authors: M
authors: M
authors: Villani
authors: M
authors: M
authors: Disumma
authors: G M
authors: GM
authors: Ottino
authors: F
authors: F
authors: Orzan
authors: A
authors: A
authors: Fubini
authors: M T
authors: MT
authors: Spinnler
authors: M R
authors: MR
authors: Conte
mesh_terms: D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000209:etiology; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008722:Methods; D008875:Middle Aged; D010166:Palliative Care; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality; D011788:Quality of Life; D012189:Retrospective Studies; D013318:Stroke Volume; D013771:Tetralogy of Fallot / Q000401:mortality / Q000601:surgery*