[A comparative evaluation of the biological action of allergens and allergoids prepared from plant pollen by the double radial immunodiffusion method].
Antisera to allergens and allergoids prepared from timothy, orchard grass, birch and wormwood pollen have been obtained and used in the double radial immunodiffusion test. The preparations of the allergoid row have been found capable of inducing immune response in laboratory animals (rabbits). Both forms of pollen preparations, allergens and allergoids, have been shown to possess common antigenic determinants reacting with antibodies present in antisera to allergens and allergoids. The absence of identity in the ratio of manifestations of gel precipitation reactions for allergoid with respect to the initial forms of allergens of individual pollen preparation has been noted.
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D000485:Allergens / Q000032:analysis / Q000276:immunology* / Q000302:isolation & purification; D000080384:Allergoids; D000818:Animals; D000939:Epitopes / Q000276:immunology; D007114:Immunization / Q000379:methods; D005779:Immunodiffusion / Q000379:methods; D010936:Plant Extracts / Q000032:analysis / Q000276:immunology* / Q000302:isolation & purification; D011058:Pollen / Q000276:immunology*; D011233:Precipitin Tests; D011817:Rabbits
D000485:Allergens; D000080384:Allergoids; D000939:Epitopes; D010936:Plant Extracts
Sravnitel'naia otsenka biologicheskoĭ aktivnosti allergenov i allergoidov, izgotovlennykh iz pyl'tsy rasteniĭ, metodom dvoĭnoĭ radial'noĭ immunodiffuzii.