[Diagnostic value of 5'nucleotidase in primary and secondary neoplasms of the liver].
64 patients with various malignant neoplasms (6 primary and 18 secondary liver cancers, 40 tumors without evidence of hepatic involvement) entered a comparative study measuring serum levels of 5'nucleotidase, AFP, TPA, CEA, CA 19-9. In primary liver cancer, 5'nucleotidase true positive rate was 100% (vs 67% of AFP, TPA, CA 19-9 and 33% of CEA); in secondary liver tumors it was 67% (vs 11% of AFP, 44% of CEA, 55% of CA 19-9 100% of TPA). Diagnostic sensitivity was 75% and specificity 90.5%.
Tozzoli
R
R
Ospedale Civile di Latisana (Udine), U.S.L. N. 88, Laboratorio Analisi Chimico-Cliniche e Microbiologia.
Risaliti
A
A
Bacelle
L
L
Perosa
A
A
Formentini
V
V
Bruno
G
G
Calandra
A
A
D015720:5'-Nucleotidase; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis; D002272:Carcinoembryonic Antigen / Q000032:analysis; D006801:Humans; D008113:Liver Neoplasms / Q000201:enzymology* / Q000556:secondary; D009708:Nucleotidases / Q000097:blood*; D010959:Tissue Plasminogen Activator / Q000032:analysis; D000509:alpha-Fetoproteins / Q000032:analysis
D015295:Antigens, Tumor-Associated, Carbohydrate; D002272:Carcinoembryonic Antigen; D000509:alpha-Fetoproteins; D009708:Nucleotidases; D015720:5'-Nucleotidase; D010959:Tissue Plasminogen Activator
Valore diagnostico della 5'nucleotidasi nelle neoplasie primitive e secondarie del fegato.