title: First clinical experience with an oxygen saturation controlled pacemaker in man.
abstract: This article describes the characteristics of a new implantable pacemaker controlled by right atrial oxygen saturation and reports the first clinical experience in man. During the observation period over 5 months, there was no evidence of malfunction due to tissue growth. The system's reaction to exercise changes proved to be quick (5 s to 17 s); decay times varied depending on the magnitude of the power previously performed. Under various exercise tests, the rate increase was linear to the stress load. Measurements of cardiac output showed the system's hemodynamic feedback and its potential self-optimization of pacing rate.
authors: I. Medical Clinic, Technical University Munich, FRG.
authors: K
authors: K
authors: Stangl
authors: A
authors: A
authors: Wirtzfeld
authors: R
authors: R
authors: Heinze
authors: M
authors: M
authors: Laule
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002304:Cardiac Pacing, Artificial / Q000379:methods; D004867:Equipment Design; D005080:Exercise Test; D006339:Heart Rate; D006801:Humans; D008297:Male; D010100:Oxygen / Q000097:blood*; D010138:Pacemaker, Artificial; D005082:Physical Exertion; D013997:Time Factors
chemical_list: D010100:Oxygen