title: Changes in rat liver mRNA for alpha-1-acid-glycoprotein, apolipoprotein E, apolipoprotein B and beta-actin after mouse recombinant tumor necrosis factor injection.
abstract: Hybridization studies using specific cDNA probes have been used to determine the specific mRNA levels for apolipoproteins B and E, alpha 1 acid glycoprotein and beta actin in extracts of rat liver. Injection of rats with recombinant mouse tumor necrosis factor had led to a rapid increase in liver mRNA levels for alpha 1 acid glycoprotein (x 12) and for beta actin (x 2.5) whereas mRNA levels for Apolipoprotein B and E remained stable over the same period.
authors: Laboratoire des proteines de la réaction inflamatoire, U.E.R. Biomédicale des Saints Pères, Paris, France.
authors: F
authors: F
authors: Delers
authors: M
authors: M
authors: Mangeney
authors: D
authors: D
authors: Raffa
authors: I
authors: I
authors: Vallet-Colom
authors: M
authors: M
authors: Daveau
authors: N
authors: N
authors: Tran-Quang
authors: C
authors: C
authors: Davrinches
authors: J
authors: J
authors: Chambaz
mesh_terms: D000199:Actins / Q000096:biosynthesis / Q000378:metabolism; D000209:Acute-Phase Proteins / Q000096:biosynthesis / Q000378:metabolism*; D000818:Animals; D001055:Apolipoproteins B / Q000096:biosynthesis / Q000378:metabolism; D001057:Apolipoproteins E / Q000096:biosynthesis / Q000378:metabolism; D015152:Blotting, Northern; D007279:Injections, Subcutaneous; D008099:Liver / Q000378:metabolism*; D008297:Male; D051379:Mice; D009961:Orosomucoid / Q000096:biosynthesis / Q000097:blood / Q000378:metabolism; D012333:RNA, Messenger / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D011994:Recombinant Proteins / Q000008:administration & dosage; D014409:Tumor Necrosis Factor-alpha / Q000008:administration & dosage*
chemical_list: D000199:Actins; D000209:Acute-Phase Proteins; D001055:Apolipoproteins B; D001057:Apolipoproteins E; D009961:Orosomucoid; D012333:RNA, Messenger; D011994:Recombinant Proteins; D014409:Tumor Necrosis Factor-alpha