Treatment of ectopic pregnancy with prostaglandin E2.
In 10 patients the treatment of ectopic pregnancy consisted of the use of 0.75 to 2.25 mg of prostaglandin E2 (Prostin E2, 1 mg/ml, Upjohn). In 8 patients PGE2 was injected in the tubal wall under laparoscopic control, in 2 under the control of vaginal ultrasound probe. The effect of the treatment was controlled by serial determinations of serum beta HCG. In 8 patients with PGE2 injected laparoscopically, negativization of beta HCG took place in 14 +/- 8 days which meant successful treatment of ectopic pregnancy. For persistently elevated beta HCG concentrations in both patients with PGE2 applied under the ultrasound control, laparotomy had to be performed.
Ribic-Pucelj
M
M
University Department of Obstetrics and Gynecology, Ljubljana, Yugoslavia.
Novak-Antolic
Z
Z
Vrhovec
I
I
D006063:Chorionic Gonadotropin / Q000097:blood*; D018997:Chorionic Gonadotropin, beta Subunit, Human; D015232:Dinoprostone / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D010446:Peptide Fragments / Q000097:blood*; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000097:blood / Q000188:drug therapy*
D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D010446:Peptide Fragments; D015232:Dinoprostone