Durable remission of pure red cell aplasia after treatment with high-dose intravenous gammaglobulin and prednisone.
Pure red cell aplasia (PRCA) is a rare disorder of erythrocyte production believed to have an autoimmune basis in most cases. Responses to a variety of immunosuppressive regimens are regularly observed, but toxicity is considerable. Brief responses to high-dose intravenous immunoglobulin (IVIg) have been previously reported. This case demonstrates a durable clinical remission of PRCA treated with IVIg and glucocorticoids.
Needleman
S W
SW
Department of Medicine, University of Maryland Cancer Center, Baltimore.
D000284:Administration, Oral; D000328:Adult; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use*; D012010:Red-Cell Aplasia, Pure / Q000188:drug therapy*; D005719:gamma-Globulins / Q000008:administration & dosage / Q000627:therapeutic use*
D005719:gamma-Globulins; D011241:Prednisone