[The action of interferon preparations on strains of Legionella of various serogroups and species].
The action of different preparations of interferon on Legionella strains has been studied in vivo and in vitro. The preparations of leukinferon at a concentration of 500 international units (I.U.) and reaferon at a concentration of 10,000 I.U. have been found to produce an inhibiting effect on Legionella strains in vitro, in a medium with carbon-yeast agar. Leukinferon at a concentration of 125 I.U. suppresses the growth of L. pneumophila also in a liquid medium. The preparation of leukinferon at a minimal concentration of 100 I.U. has been found to suppress the development of lethal infection in chick embryos infected with L. pneumophila strain Philadelphia 1.
Tartakovskiĭ
I S
IS
Marakusha
B I
BI
Kuznetsov
V V
VV
Nebozhina
L V
LV
Prozorovskiĭ
S V
SV
D000818:Animals; D002642:Chick Embryo; D004305:Dose-Response Relationship, Drug; D004917:Erythromycin / Q000494:pharmacology; D007372:Interferons / Q000494:pharmacology*; D007875:Legionella / Q000145:classification / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D012703:Serotyping; D013045:Species Specificity
D004917:Erythromycin; D007372:Interferons
Deĭtsvie preparatov interferona na shtammy legionell razlichnykh serogrupp i vidov.