Mast cells and IgE-mediated release of histamine and arachidonate metabolites from human kidney.
We report a pilot study of mast cells and IgE-mediated release of histamine, leukotrienes and thromboxanes from human kidney. The results together with previous findings in the guinea-pig and rat suggest that mast cells and IgE may play an important role in kidney disease.
Assem
E S
ES
Department of Pharmacology, University College London, UK.
Abdullah
N A
NA
Cowie
A G
AG
D006636:Histamine Release; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D066298:In Vitro Techniques; D007668:Kidney / Q000276:immunology* / Q000378:metabolism; D008407:Mast Cells / Q000276:immunology; D013189:SRS-A / Q000378:metabolism; D013931:Thromboxanes / Q000378:metabolism
D013189:SRS-A; D013931:Thromboxanes; D007073:Immunoglobulin E