[Effect of calcium chloride on interferon production and the biosynthesis of cellular macromolecules].
The influence of calcium chloride in production of interferon and biosynthesis of cell proteins, RNA and DNA in the cultures of chick embryo fibroblast cells and murine cells L-929 in response to induction of the cells by poly(I).poly(C) was studied. It was shown that calcium ions in concentrations of 10 to 30 mM markedly increased formation of interferon in the cell cultures.
Askarkhodzhaev
N A
NA
Tazulakhova
E B
EB
Ershov
F I
FI
D000818:Animals; D002122:Calcium Chloride / Q000494:pharmacology*; D002478:Cells, Cultured; D002642:Chick Embryo; D004247:DNA / Q000096:biosynthesis / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D007372:Interferons / Q000032:analysis / Q000096:biosynthesis*; D046911:Macromolecular Substances; D051379:Mice; D011070:Poly I-C / Q000494:pharmacology; D012313:RNA / Q000096:biosynthesis / Q000187:drug effects
D046911:Macromolecular Substances; D012313:RNA; D004247:DNA; D007372:Interferons; D002122:Calcium Chloride; D011070:Poly I-C
Vliianie khlorida kal'tsiia na produktsiiu interferona i biosintez kletochnykh makromolekul.