Atypical fibroxanthoma: two unusual variants.
Two unusual fibroxanthomas were studied by light microscopy. The first case contained numerous osteoclast-like cells and resembled malignant giant cell tumour of soft tissues, a variant of malignant fibrous histiocytoma. Osteoclast-like giant cells were negative for lysozyme and alpha-1-antitrypsin. The second case contained areas of chondroid differentiation which resembled chondrosarcoma. Tumour cells within the cartilaginous areas were positive for S100 protein.
Wilson
P R
PR
Department of Dermatology, Royal Brisbane Hospital, Cairns, Australia.
Strutton
G M
GM
Stewart
M R
MR
D000368:Aged; D000369:Aged, 80 and over; D002813:Chondrosarcoma / Q000473:pathology; D005260:Female; D005350:Fibroma / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D014644:Genetic Variation; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000378:metabolism; D009113:Muramidase / Q000378:metabolism; D009418:S100 Proteins / Q000378:metabolism; D012878:Skin Neoplasms / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D000515:alpha 1-Antitrypsin / Q000378:metabolism
D009418:S100 Proteins; D000515:alpha 1-Antitrypsin; D007633:Keratins; D009113:Muramidase