Serum protein electrophoresis in spontaneous canine hyperadrenocorticalism.
The serum protein concentrations of dogs with confirmed spontaneous hyperadrenocorticalism were determined by agarose gel electrophoresis before and during treatment with mitotane. In untreated animals a significant increase was detected in the mean concentration of total protein and the mean concentration and percentage of alpha-2 globulin. The mean concentration and percentage of albumin and gamma-globulin were significantly decreased. In animals on treatment the mean concentration of total proteins and the mean concentration and percentage of beta-2 globulin were significantly reduced.
van den Broek
A H
AH
Department of Veterinary Clinical Studies, Royal (Dick) School of Veternary Studies, Summerhall, Edinburgh.
Lida
J
J
D000303:Adrenal Cortex Diseases / Q000097:blood / Q000188:drug therapy / Q000662:veterinary*; D000510:Alpha-Globulins / Q000032:analysis; D000818:Animals; D001609:Beta-Globulins / Q000032:analysis; D001797:Blood Protein Electrophoresis; D001798:Blood Proteins / Q000032:analysis*; D004283:Dog Diseases / Q000097:blood* / Q000188:drug therapy; D004285:Dogs; D008939:Mitotane / Q000627:therapeutic use; D012709:Serum Albumin / Q000032:analysis; D005719:gamma-Globulins / Q000032:analysis
D000510:Alpha-Globulins; D001609:Beta-Globulins; D001798:Blood Proteins; D012709:Serum Albumin; D005719:gamma-Globulins; D008939:Mitotane