Virulence associated plasmid and R-plasmid curing in Yersinia enterocolitica by some tricyclic compounds.
The virulence plasmid which confers calcium-dependent growth in Yersinia enterocolitica and the R-plasmid of a Y. enterocolitica strain were eliminated by several, tricyclic psychopharmacons, e.g. promethazine, imipramine, and (+) and (-)-butaclamols.
Molnár
J
J
Institute of Microbiology, University Medical School, Szeged, Hungary.
Nakamura
M J
MJ
D000929:Antidepressive Agents, Tricyclic / Q000494:pharmacology*; D002069:Butaclamol / Q000494:pharmacology; D002118:Calcium / Q000378:metabolism; D007099:Imipramine / Q000494:pharmacology; D010957:Plasmids / Q000187:drug effects*; D011398:Promethazine / Q000494:pharmacology; D011815:R Factors / Q000187:drug effects; D014774:Virulence; D015008:Yersinia enterocolitica / Q000187:drug effects* / Q000378:metabolism / Q000472:pathogenicity
D000929:Antidepressive Agents, Tricyclic; D002069:Butaclamol; D011398:Promethazine; D007099:Imipramine; D002118:Calcium