title: [Heterogeneity of epithelial cells in the human thymus during early ontogeny (an immunohistochemical study)].
abstract: An immunohistochemical study of thymic epithelial cells at an early stage of prenatal development of man (II-III lunar month of pregnancy) was carried out. Serial cryostatic sections were prepared by a standardized method (Takacs, 1987) with monoclonal antibodies against four types of tonofilament-bound keratinic antigens (BH11, BG3, AG3, T2/30). There were phenotypic-heterogeneity, caused by differences in the expression of keratinic antigens, as well as regional peculiarities in inner thymic distribution of various types of keratin-positive epithelial cells. The obtained results are discussed in connection with the possibility of securing specific epithelial microencirclement of thymic lymphocytes during their proliferation and differentiation at early ontogeny.
authors: Ts
authors: Ts
authors: Marinova
mesh_terms: D000941:Antigens / Q000032:analysis; D004847:Epithelial Cells; D004848:Epithelium / Q000276:immunology / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D013601:T-Lymphocytes / Q000276:immunology; D013950:Thymus Gland / Q000196:embryology* / Q000276:immunology / Q000378:metabolism
chemical_list: D000941:Antigens; D007633:Keratins
vernacular_title: Kheterogennost na epitelnite kletki na timusa u chovek v rannata ontogeneza (imunokhistokhimichno izsledvane).