Pathogenesis of AIDS-associated Kaposi's sarcoma.
Kaposi's sarcoma presents the oncologist with a myriad of unanswered questions. What accounts for the genesis, distribution, and natural history of this tumor? How could a tumor with such a singular histologic appearance occur in such diverse clinical circumstances? What accounts for the unusual geographic, ethnic, and demographic features of Kaposi's sarcoma? Clearly, the answers to these questions will involve a multifactorial etiology, and may only be arrived at by methodical, piecemeal dissection of each question.
Ziegler
J L
JL
School of Medicine, University of California, San Francisco.
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D043925:Angiogenesis Inducing Agents / Q000032:analysis; D004727:Endothelium / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000032:analysis; D009389:Neovascularization, Pathologic / Q000209:etiology; D012514:Sarcoma, Kaposi / Q000209:etiology* / Q000378:metabolism / Q000473:pathology
D043925:Angiogenesis Inducing Agents