[Modelling of ion channel properties and study of channel role in the formation of impulse activity of the neuron].
The electron analogue of a neuron working in real time scale is suggested. The sequence of signals' transformation in this analogue is in line with synaptic, postsynaptic membrane and somatic processes. Data on the synapse as on a "key" and on the postsynaptic membrane as on the ion channel with conductivity changed under the influence of a mediator and intracellular potential permit making the neuron analog on the basis of the pulse generator with the possibility to reproduce the synaptic apparatus activity and the neuronal dendrites' structure. The processes of the impulse flow transformation characteristic for neurons of different types, for example motoneurons and Renshow cells are modelled by changing the parameters of the membrane resistance and capacity. The study of simple networks has shown possible to use the suggested analogues for investigating principles of neuronal structure organizations and mechanisms of neuronal interactions, particularly in the motor control system.
Romanov
S P
SP
D003712:Dendrites / Q000502:physiology; D005071:Evoked Potentials; D007473:Ion Channels / Q000502:physiology*; D008564:Membrane Potentials; D008959:Models, Neurological; D009046:Motor Neurons / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D013569:Synapses / Q000502:physiology
D007473:Ion Channels
Modelirovanie svoĭstva ionnogo kanala i issledovanie ego roli v formirovanii impul'snoĭ aktivnosti neĭrona.