title: Cord blood basophil releasability: a predictive marker for allergy?
abstract: Liberation of histamine and LTC4 by cord-blood basophils was measured in the newborn from healthy and atopic parents. The cord-blood basophils of the second classification produced more histamine than those from the first, after challenge with anti-IgE. Thus, a newborn from atopic parent(s) probably carries more fixed IgE on the basophils than a newborn from healthy parents and so the capacity of cord-blood basophils to liberate mediators may be a good marker of allergy.
authors: Istituto di Clinica Medica II, Università di Milano, Italy.
authors: A
authors: A
authors: Miadonna
authors: A
authors: A
authors: Tedeschi
authors: E
authors: E
authors: Leggieri
authors: G
authors: G
authors: Motta
authors: C
authors: C
authors: Fabbri
authors: M
authors: M
authors: Lorini
authors: G
authors: G
authors: Lucci
authors: M
authors: M
authors: Froldi
authors: A
authors: A
authors: Marini
authors: C
authors: C
authors: Zanussi
mesh_terms: D000328:Adult; D001491:Basophils / Q000276:immunology* / Q000378:metabolism; D005312:Fetal Blood / Q000276:immunology*; D006636:Histamine Release; D006801:Humans; D006967:Hypersensitivity / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D007073:Immunoglobulin E / Q000032:analysis; D007231:Infant, Newborn; D013189:SRS-A / Q000096:biosynthesis
chemical_list: D013189:SRS-A; D007073:Immunoglobulin E