Low molecular weight RNA of Drosophila cells which is induced by heat shock--I. Synthesis and its effect on protein synthesis.
When Drosophila cells were heat shocked, low molecular weight RNA of a novel type was synthesized and accumulated in the cytoplasm. This RNA, which is about 320 nucleotides long, inhibited the translation of Drosophila mRNAs in rabbit reticulocyte lysate. It remains to be clarified whether this RNA is involved in the regulation mechanism of heat shock at the translational level.
Kawata
Y
Y
Department of Biology, College of Arts and Sciences, University of Tokyo, Japan.
Fujiwara
H
H
Ishikawa
H
H
D000818:Animals; D002478:Cells, Cultured; D004331:Drosophila melanogaster / Q000235:genetics / Q000378:metabolism*; D006360:Heat-Shock Proteins / Q000096:biosynthesis* / Q000235:genetics; D006358:Hot Temperature / Q000009:adverse effects; D008970:Molecular Weight; D014176:Protein Biosynthesis; D012313:RNA / Q000096:biosynthesis* / Q000235:genetics
D006360:Heat-Shock Proteins; D012313:RNA