Low serum alpha-fetoprotein level and sex chromosome monosomy.
A case of 45,X karyotype in association with low maternal serum alpha-fetoprotein levels is reported. Previous cases of trisomy have been linked to low alpha-fetoprotein levels. Cases of sex chromosome aneuploidy may be included in the group of aneuploidies with low levels of maternal serum alpha-fetoprotein.
Winston
Y E
YE
Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston 29425.
Horger
E O
EO
Van Dorsten
J P
JP
D000328:Adult; D000782:Aneuploidy; D002872:Chromosome Deletion; D005260:Female; D005315:Fetal Diseases / Q000097:blood*; D006801:Humans; D009006:Monosomy; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012729:Sex Chromosome Aberrations / Q000097:blood*; D000509:alpha-Fetoproteins / Q000032:analysis*
D000509:alpha-Fetoproteins