Fast increase of proteinase inhibitors in necrotic collagenous tissue.
Using the PAP immunohistochemical technique, accumulation of two proteinase inhibitors, alpha-1-antichymotrypsin and alpha-2-macroglobulin, can be detected at the edges of collagenous fibers in the corium after slash wounds of the skin. This accumulation was observed within a survival time of 10-30 min. It, however, is not detectable in postmortally inflicted trauma.
Oehmichen
M
M
Department of Forensic Medicine, University of Cologne, F.R.G.
D006801:Humans; D007124:Immunoenzyme Techniques; D009336:Necrosis; D011180:Postmortem Changes; D011480:Protease Inhibitors / Q000032:analysis*; D012867:Skin / Q000201:enzymology / Q000293:injuries* / Q000473:pathology; D013997:Time Factors; D014951:Wounds, Stab / Q000201:enzymology*; D000514:alpha 1-Antichymotrypsin / Q000032:analysis; D000511:alpha-Macroglobulins / Q000032:analysis
D011480:Protease Inhibitors; D000514:alpha 1-Antichymotrypsin; D000511:alpha-Macroglobulins