title: [The pharmacology of recombinant hirudin].
abstract: A review about comprehensive studies on pharmacological properties of hirudin produced by genetic engineering is given. Anticoagulant effects, influence on platelet functions, studies on toxicity and side effects as well as the pharmacokinetic behaviour and antithrombotic actions of this highly effective thrombin inhibitor are described.
authors: Institut für Pharmakologie und Toxikologie, Medizinischen Akademie Erfurt.
authors: B
authors: B
authors: Kaiser
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000187:drug effects; D004285:Dogs; D005343:Fibrinolytic Agents; D006629:Hirudins / Q000009:adverse effects / Q000493:pharmacokinetics / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D051381:Rats; D011994:Recombinant Proteins
chemical_list: D005343:Fibrinolytic Agents; D006629:Hirudins; D011994:Recombinant Proteins
vernacular_title: Zur Pharmakologie von rekombinantem Hirudin.