Vesicle-membrane fusion. Observation of simultaneous membrane incorporation and content release.
Vesicle fusion, the central process of neurotransmitter release and hormonal secretion, is a complex process culminating in simultaneous incorporation of vesicle membrane into the plasma membrane and release of the vesicular contents extracellularly. This report describes simultaneous observation of membrane incorporation and content release using a model system composed of a planar bilayer and dye-filled vesicles.
Woodbury
D J
DJ
Department of Physiology and Biophysics, University of California, Irvine 92717.
Hall
J E
JE
D001425:Bacterial Outer Membrane Proteins / Q000502:physiology*; D005089:Exocytosis; D007473:Ion Channels / Q000502:physiology*; D007700:Kinetics; D008051:Lipid Bilayers; D008954:Models, Biological; D018272:Porins; D013050:Spectrometry, Fluorescence
D001425:Bacterial Outer Membrane Proteins; D007473:Ion Channels; D008051:Lipid Bilayers; D018272:Porins