The supramammillary region of the cat sends substance P-like immunoreactive axons to the hippocampal formation and the entorhinal cortex.
A combined method of the tracing of WGA-HRP (wheat germ agglutinin-conjugated horseradish peroxidase) and the immunohistochemistry of substance P (SP) showed that many SP-like immunoreactive neurons in the supramammillary nucleus of cat hypothalamus sent their axons to the hippocampal formation. SP-like immunoreactive axons in the hippocampal formation and entorhinal cortex were markedly reduced in number ipsilaterally after placing an electrothermic lesion in the supramammillary region of the hypothalamus.
Ino
T
T
Department of Anatomy (1st Division), Faculty of Medicine, Kyoto University, Japan.
Itoh
K
K
Sugimoto
T
T
Kaneko
T
T
Kamiya
H
H
Mizuno
N
N
D000818:Animals; D002415:Cats; D002540:Cerebral Cortex / Q000032:analysis* / Q000166:cytology; D006624:Hippocampus / Q000032:analysis* / Q000166:cytology; D006735:Horseradish Peroxidase; D007031:Hypothalamus / Q000032:analysis* / Q000166:cytology; D007150:Immunohistochemistry; D009434:Neural Pathways / Q000033:anatomy & histology; D013373:Substance P / Q000032:analysis*; D018998:Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; D014909:Wheat Germ Agglutinins
D018998:Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; D014909:Wheat Germ Agglutinins; D013373:Substance P; D006735:Horseradish Peroxidase