title: Epitope analysis: biotinylated short peptides as inhibitors of anti-peptide antibody.
abstract: The interaction of anti-melittin antisera with melittin-coated ELISA plates could be inhibited by biotinylated peptides of the C terminal epitope which is one of three defined antigenic sites on the hexacosapeptide melittin. Non-biotinylated short peptides and peptide derivatives were inactive. It is suggested that biotinylation of epitopic peptides enhances their inhibitory properties in a methodologically useful way.
authors: University of Bern, Institute for Clinical Immunology, Inselspital, Switzerland.
authors: R
authors: R
authors: Von Grünigen
authors: C H
authors: CH
authors: Schneider
mesh_terms: D000595:Amino Acid Sequence; D001514:Bee Venoms / Q000276:immunology*; D001667:Binding, Competitive; D001710:Biotin; D000939:Epitopes; D008555:Melitten / Q000276:immunology*; D008969:Molecular Sequence Data; D010455:Peptides / Q000276:immunology*; D013329:Structure-Activity Relationship
chemical_list: D001514:Bee Venoms; D000939:Epitopes; D010455:Peptides; D008555:Melitten; D001710:Biotin