[A method of searching for amphipathic structures in protein sequences].
A simple method for searching amphipathic helices based on estimation of correlation between hydrophobicity distribution and periodic function is proposed. The method was examined in a series of proteins with known T-cell epitopes, which are mostly amphipathic helices. The predictive power of the method is discussed.
Gabriélian
A E
AE
Ivanov
V S
VS
Kozhich
A T
AT
D000465:Algorithms; D000595:Amino Acid Sequence; D000939:Epitopes / Q000032:analysis; D011487:Protein Conformation; D013329:Structure-Activity Relationship; D013601:T-Lymphocytes / Q000276:immunology
D000939:Epitopes
Metod poiska amfipatichnykh struktur v belkovykh posledovatel'nostiakh