Tumor markers in non-malignant diseases.
This paper reviews the specificity of tumor markers recently introduced in clinical use, namely CA 19-9, CA 125, CA 15-3, CA 50 and SCC antigen. It appears that a large number of either biological conditions (age, sex, pregnancy, menstruation etc.), intoxication (smoking and alcohol addictions) or various non-malignant diseases do affect the serum levels of tumor markers. These data are of practical use in the interpretation of tumor marker determinations in the follow-up of cancer patients.
Touitou
Y
Y
Department of Biochemistry, Faculté de Médecine, Pitié-Salpêtrière, Paris, France.
Bogdan
A
A
D000951:Antigens, Neoplasm / Q000032:analysis; D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor / Q000097:blood*; D000939:Epitopes / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy
D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor; D000939:Epitopes