title: A comparison between changes in rat parotid protein composition 1 and 12 weeks following surgical sympathectomy.
abstract: One week after surgical sympathectomy the amylase and protein concentrations of parotid glands were increased by 250 and 51% respectively. Whilst these concentration changes had partly returned to normal after 12 weeks, major differences still remained in the protein composition of parotid glands. Anion-exchange chromatography showed that proline-rich proteins were progressively reduced and that the relative proportions of other proteins changed variably. These results indicate that normal synthesis of proline-rich proteins requires on-going stimulation of the cells via the sympathetic nerve. In the absence of sympathetic nerve activity there was initially an increased synthesis of amylase which then returned towards normal.
authors: Department of Oral Pathology, King's College School of Medicine and Dentistry, London.
authors: G B
authors: GB
authors: Proctor
authors: B
authors: B
authors: Asking
mesh_terms: D000681:Amylases / Q000378:metabolism; D000818:Animals; D002852:Chromatography, Ion Exchange; D003545:Cysteine / Q000032:analysis; D007700:Kinetics; D008297:Male; D010306:Parotid Gland / Q000378:metabolism*; D011392:Proline / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains; D012471:Salivary Proteins and Peptides / Q000032:analysis / Q000378:metabolism*; D013562:Sympathectomy
chemical_list: D012471:Salivary Proteins and Peptides; D011392:Proline; D000681:Amylases; D003545:Cysteine