[Pepsinogen messenger RNA of human gastric mucosa and stomach cancer].
The cell-free translation method has shown that pepsinogen mRNA is a predominant fraction in the total poly(A)+ RNA from human gastric mucosa. The pepsinogen protein with the molecular weight of 45 kDa has been identified. The level of pepsinogen mRNA decreased in tumours as compared with normal mucosa but in most cases pepsinogen mRNA synthesis depression was not total.
Kalinovskiĭ
V P
VP
Glebov
A V
AV
Seĭts
I F
IF
D004591:Electrophoresis, Polyacrylamide Gel / Q000379:methods; D005753:Gastric Mucosa / Q000032:analysis*; D006801:Humans; D010435:Pepsinogens / Q000032:analysis*; D011061:Poly A / Q000032:analysis; D014176:Protein Biosynthesis; D012313:RNA / Q000032:analysis; D012333:RNA, Messenger / Q000032:analysis*; D012334:RNA, Neoplasm / Q000032:analysis*; D013274:Stomach Neoplasms / Q000032:analysis*
D010435:Pepsinogens; D012333:RNA, Messenger; D012334:RNA, Neoplasm; D011061:Poly A; D012313:RNA
Izuchenie informatsionnoĭ RNK pepsinogena slizistoĭ obolochki i raka zheludka cheloveka.