Anti-inflammatory compounds from Sideritis javalambrensis n-hexane extract.
The anti-inflammatory activities of the n-hexane extract of Sideritis javalambrensis and several purified fractions were investigated using the carrageenan mouse paw edema test. Progressive fractionation led to the isolation of the active principles ent-16-hydroxy-13-epimanoyl oxide [1] and esters of tyrosol with palmitic, stearic, behenic, and lignoceric acids.
Alcaraz
M J
MJ
Departamento de Farmacología y Farmacotecnia, Facultad de Farmacia, Universitat de València, Spain.
Jimenez
M J
MJ
Valverde
S
S
Sanz
J
J
Rabanal
R M
RM
Villar
A
A
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000302:isolation & purification*; D004952:Esters; D006586:Hexanes; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D051379:Mice; D010626:Phenylethyl Alcohol / Q000031:analogs & derivatives / Q000302:isolation & purification / Q000494:pharmacology; D010944:Plants / Q000032:analysis*; D013729:Terpenes / Q000302:isolation & purification / Q000494:pharmacology*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004952:Esters; D006586:Hexanes; D013729:Terpenes; C062200:16-hydroxy-13-manoyl oxide; C011867:4-hydroxyphenylethanol; C026385:n-hexane; D010626:Phenylethyl Alcohol