Three types of vitronectin in human blood.
Vitronectin is a cell-adhesive glycoprotein in serum and plasma, also termed serum spreading factor and complement S-protein. It consists of a mixture of a polypeptide of molecular weight 75 kilodalton (kDa) and its nicked product of 65 kDa plus 10 kDa. By a quantitative immunoblotting assay, human blood samples could be classified into three distinct vitronectin types; type I (58% of the population) was 75 kDa rich and 65 kDa poor, type II (35% of the population) contained approximately equal amounts of 75 kDa and 65 kDa, and type III (5% of the population) was 75 kDa poor and 65 kDa rich. The vitronectin type did not correlate with age, sex, or ABO blood type.
Kubota
K
K
Department of Biology, Ochanomizu University, Tokyo, Japan.
Katayama
S
S
Matsuda
M
M
Hayashi
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M
D000017:ABO Blood-Group System; D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D006023:Glycoproteins / Q000032:analysis / Q000097:blood* / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008970:Molecular Weight; D012737:Sex Factors; D019096:Vitronectin
D000017:ABO Blood-Group System; D006023:Glycoproteins; D019096:Vitronectin