Atypical polypoid adenomyoma of the uterus. An immunohistochemical study of a case.
We studied one case of atypical polypoid adenomyoma of the uerus immunohistochemically using antisera against keratins, vinentin, S-100 protein, desmin and actin. The stromal cells were reactive with anti-actin and antidesmin antibodies suggesting a muscular phenotype and confirming previous ultrastructural data. Immunohistochemical investigations have proved to be useful in differential diagnosis of APA with invasive adenocarcinoma, adenosarcoma and adenofibroma of the endometrium.
Di Palma
S
S
Divisione di Anatomia Patologica e Citologia, Istituto Nazionale Tumori, Milano, Italy.
Santini
D
D
Martinelli
G
G
D000199:Actins / Q000378:metabolism; D000230:Adenocarcinoma / Q000378:metabolism; D000232:Adenofibroma / Q000378:metabolism; D003893:Desmin / Q000378:metabolism; D003937:Diagnosis, Differential; D004715:Endometriosis / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000378:metabolism; D008875:Middle Aged; D009418:S100 Proteins / Q000378:metabolism; D014594:Uterine Neoplasms / Q000378:metabolism* / Q000473:pathology; D014746:Vimentin / Q000378:metabolism
D000199:Actins; D003893:Desmin; D009418:S100 Proteins; D014746:Vimentin; D007633:Keratins