title: Hemorrhagic bullous amyloidosis. A histologic, immunocytochemical, and ultrastructural study of two patients.
abstract: In patients with bullous hemorrhagic amyloidosis of the skin, the skin lesions were the first manifestations of a plasma cell dyscrasia. Both cases were characterized by similar clinical, histologic, and ultrastructural findings showing an intradermal blister within deposits of amyloid substances. Immunohistologic investigations with a panel of antibodies directed against amyloid fibril proteins showed reactivity of the amyloid deposits with an anti-A lambda serum in both patients.
authors: Department of Dermatology, Ludwig-Maximilians University, Munich, West Germany.
authors: T
authors: T
authors: Bieber
authors: T
authors: T
authors: Ruzicka
authors: R P
authors: RP
authors: Linke
authors: R
authors: R
authors: von Kries
authors: G
authors: G
authors: Goerz
authors: O
authors: O
authors: Braun-Falco
mesh_terms: D000368:Aged; D000682:Amyloid / Q000032:analysis; D000686:Amyloidosis / Q000150:complications / Q000473:pathology*; D001485:Basement Membrane / Q000473:pathology; D005260:Female; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D007124:Immunoenzyme Techniques; D012867:Skin / Q000032:analysis / Q000473:pathology* / Q000648:ultrastructure; D012872:Skin Diseases, Vesiculobullous / Q000150:complications / Q000473:pathology*; D013194:Staining and Labeling
chemical_list: D000682:Amyloid