Surface view patterns of intrinsic and extrinsic cortical connections of area 17 in a prosimian primate.
Patterns of cortical connections were studied in brain sections cut parallel to the surface of mechanically flattened cortex after single, double, or multiple injections of wheatgerm agglutinin conjugated to horseradish peroxidase (WGA-HRP) in area 17 of galagos (Galago crassicaudatus). Intrinsic connections of area 17 included a systematic pattern of patches of labeled cells and terminations associated with blobs of high cytochrome oxidase activity. The patches of connections extended with decreasing density for a distance of 2 mm or more from the margins of injection sites. Injections also revealed dense interconnections with area 18 (V-II) and the middle temporal visual area (MT). Single injections in area 17 produced several foci of label in both area 18 and MT, suggesting that a given location in area 17 is interconnected with subsets of processing modules in both of these fields. Injections including dorsolateral area 17 also labeled cortex between area 18 and MT. Finally, most injections in area in the temporal lobe.
Cusick
C G
CG
Department of Psychology, Vanderbilt University, Nashville, TN 37240.
Kaas
J H
JH
D000818:Animals; D001370:Axonal Transport; D001921:Brain / Q000033:anatomy & histology; D002540:Cerebral Cortex / Q000033:anatomy & histology*; D005701:Galago / Q000033:anatomy & histology*; D006735:Horseradish Peroxidase; D013045:Species Specificity; D018998:Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; D014909:Wheat Germ Agglutinins
D018998:Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; D014909:Wheat Germ Agglutinins; D006735:Horseradish Peroxidase