[Levels of homovanillic acid and 5-hydroxyindoleacetic acid in the cerebrospinal fluid in patients with focal cerebral ischemia].
The investigated group comprised 35 patients where clinical examination revealed focal cerebral ischaemia in the area of the a. cerebri media. In the group of elderly patients above 60 years, as compared with controls, the homovanillic acid (HVA) and 5-hydroxyindolacetic acid (5-HIAA) concentration in cerebrospinal fluid was elevated. In the group of patients under 60 years no changes in the concentration of these metabolites were found. In older patients the increased level of metabolites in cerebrospinal fluid persisted also after three days following the attack, while in younger patients the elevated HVA and 5-HIAA levels were found only in specimens collected up to three days.
Chavko
M
M
Kehr
J
J
Vasková
M
M
Eiben
E
E
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006719:Homovanillic Acid / Q000134:cerebrospinal fluid*; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000134:cerebrospinal fluid*; D002546:Ischemic Attack, Transient / Q000134:cerebrospinal fluid*; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D006897:Hydroxyindoleacetic Acid; D006719:Homovanillic Acid
Koncentrácia kyseliny homovanilovej a 5-hydroxyindoloctovej v CSL u pacientov s loziskovou ischémiou mozgu.