[Comparative immunochemical characteristics and serological activity of the antigens of Cysticercus tenuicollis and Taenia hydatigena].
Data are given on immunochemical analysis and serological activity of different antigens from larval and imaginal forms of Taenia hydatigena. Considerable heterogeneity and close antigenic affinity of the parasite's extracts under study both between each other and with the host's proteins, excluding the antigens from T. hydatigena, which has no common components with the latter, are established. In the homologous system in each extract under study there were recognised no less than 5 to 9 antigenic components. It is shown, however, by the method of adsorption of heterologous antibodies that the number of specific antigens in each of them does not exceed 1 or 2. All antigens happened to be serologically active, but the highest diagnostic efficiency was shown by extracts from scolices of C. tenuicollis and T. hydatigena. Antiparasitic antibodies were followed by these antigens in the sera of experimentally infected sucking pigs from the 10th day of the infection. They reached their maximum level on the 24th day and then was observed a gradual fall of the titre of specific antibodies, the level of which by the 115th day did not actually differ from initial values. The highest sensitivity and specificity in the immunoenzyme reaction under experimental conditions was displayed by the extracts from scolices of C. tenuicollis.
Berezhko
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D000818:Animals; D000909:Antibodies, Helminth / Q000032:analysis; D000918:Antibody Specificity; D000947:Antigens, Helminth / Q000032:analysis*; D003551:Cysticercosis / Q000276:immunology / Q000662:veterinary; D003552:Cysticercus / Q000276:immunology*; D004285:Dogs / Q000469:parasitology; D000939:Epitopes / Q000032:analysis; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D007124:Immunoenzyme Techniques; D007150:Immunohistochemistry; D007814:Larva / Q000276:immunology; D013552:Swine / Q000469:parasitology; D013553:Swine Diseases / Q000276:immunology; D013621:Taenia / Q000276:immunology*; D013622:Taeniasis / Q000276:immunology / Q000662:veterinary
D000909:Antibodies, Helminth; D000947:Antigens, Helminth; D000939:Epitopes
Sravnitel'naia immunokhimicheskaia kharakteristika i serologicheskaia aktivnost' antigenov Cysticercus tenuicollis i Taenia hydatigena.