title: Salivary levels of gramicidin after use of a tyrothricin-containing gargle/mouth-wash and tyrothricin lozenges.
abstract: Three pharmaceutical preparations for the disinfection of the oropharynx were tested with regard to the gramicidin concentration obtained in the saliva after their appropriate application. Peak values followed a dose-concentration relationship and were highest after sucking a lozenge containing 10 mg tyrothricin (mean 109.3 mg/L) followed by that of a gargle/mouth-wash containing 667 mg tyrothricin/L (mean 21.1 mg/L) and of a lozenge containing 4 mg tyrothricin (mean 14.4 mg/L).
authors: Department of Medicine, Biochemie Ges. m.b.H., Vienna, Austria.
authors: C
authors: C
authors: Matula
authors: G
authors: G
authors: Nahler
authors: F
authors: F
authors: Kreuzig
mesh_terms: D000328:Adult; D005260:Female; D006096:Gramicidin / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009067:Mouthwashes; D012463:Saliva / Q000032:analysis*; D014449:Tyrothricin / Q000008:administration & dosage*
chemical_list: D009067:Mouthwashes; D014449:Tyrothricin; D006096:Gramicidin