Variations in antigen-specific histamine release related with immunotherapeutic treatment.
The present study analyzes the variations in the percentage of histamine release of 34 allergic patients receiving immunotherapy; the determinations were realized at two different periods of their immunotherapeutic treatment, that is, at an average of 18 months (mite allergy group) and 12 months (grass allergy group) after the first determination. We found that the percentage of histamine release decreased significantly in the second determination in relation to the first, and that this decrease was more intense when more time elapsed between both determinations.
Castillo
J G
JG
Departamento de Alergologia, Facultad de Medicina, Universidad de Navarra, Pamplona, Spain.
Gamboa
P M
PM
Oehling
A
A
Wong
E
E
de la Cuesta
C G
CG
D000485:Allergens / Q000276:immunology; D000818:Animals; D039741:Antigens, Dermatophagoides; D004391:Dust; D005069:Evaluation Studies as Topic; D006636:Histamine Release; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology / Q000628:therapy*; D007167:Immunotherapy; D008925:Mites / Q000276:immunology; D006109:Poaceae / Q000276:immunology; D011058:Pollen / Q000276:immunology
D000485:Allergens; D039741:Antigens, Dermatophagoides; D004391:Dust