title: Tumoral calcinosis in scleroderma.
abstract: A 36-year-old female patient with scleroderma/Sjögren's syndrome developed multiple cystic tumors on the dorsal aspect of her left hand, right elbow, and left shoulder joint two years after the onset of scleroderma. Histologically, amorphous eosinophilic substances located in subcutaneous tissue showed a strong positive reaction to PTAH and rosindole stain, and focal positive reaction to Von Kossa stain. Rheumatoid rice body like substances with chalky fluid were discharged from tumoral lesions. From these results, this case was diagnosed as tumoral calcinosis secondary to connective tissue degeneration due to the pathogenetic mechanism underlying scleroderma/Sjögren's syndrome.
authors: I
authors: I
authors: Katayama
authors: K
authors: K
authors: Higashi
authors: H
authors: H
authors: Mukai
authors: K
authors: K
authors: Nishioka
authors: S
authors: S
authors: Nishiyama
mesh_terms: D000328:Adult; D002114:Calcinosis / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D007596:Joints / Q000473:pathology; D012595:Scleroderma, Systemic / Q000150:complications*; D012859:Sjogren's Syndrome / Q000175:diagnosis; D013194:Staining and Labeling