Duodenal melanosis.
Melanosis duodeni is a rare benign condition that has only recently been recognized. We describe melanosis duodeni in a 64-year-old woman who had been taking propranolol and furosemide for 5 years. The cause and clinical significance of this unusual finding remain obscure. But we assume that it is an idiosyncratic metabolism of benzene-ring-containing drugs resulting in the accumulation of pigment in the duodenal mucosa.
Kuo
Y C
YC
Department of Gastroenterology, Chang Gung Memorial Hospital, Lin-Kou Medical Center, Taipei, Taiwan, Republic of China.
Wu
C S
CS
D004378:Duodenal Diseases / Q000473:pathology*; D004384:Duodenoscopy; D004386:Duodenum / Q000032:analysis; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000032:analysis; D008264:Macrophages / Q000032:analysis; D008543:Melanins / Q000032:analysis; D008548:Melanosis / Q000473:pathology*; D008875:Middle Aged; D012835:Silver Nitrate; D013194:Staining and Labeling
C051037:Fontana-Masson stain; D008543:Melanins; D012835:Silver Nitrate