[Use of recombinant proteins carrying antigenic determinants of the envelope proteins of AIDS virus in the diagnosis of acquired immunodeficiency syndrome].
The testing of sera from patients with AIDS and AIDS-related complex, using ELISA with recombinant env protein produced by E. coli, gave a 94% coincidence with the results obtained on "Organon" test-system. Sera samples that gave different results in two tests lacked antibodies to env-encoded proteins, as revealed by immunoblotting assay. The application of the above test for the estimation of the disease prognosis is discussed.
Bukrinskiĭ
M I
MI
Barsov
E V
EV
Karamov
E V
EV
D000386:AIDS-Related Complex / Q000175:diagnosis; D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis*; D004797:Enzyme-Linked Immunosorbent Assay; D000939:Epitopes / Q000032:analysis; D004926:Escherichia coli / Q000276:immunology; D006678:HIV / Q000276:immunology*; D006801:Humans; D011379:Prognosis; D011994:Recombinant Proteins; D014759:Viral Envelope Proteins / Q000032:analysis / Q000276:immunology*
D000939:Epitopes; D011994:Recombinant Proteins; D014759:Viral Envelope Proteins
Ispol'zovanie rekombinantnogo belka, nesushchego antigennye determinanty obolochechnogo belka virusa SPID, dlia diagnostiki sindroma priobretennogo immunodefitsita.