Psychobiological concomitants of history of suicide attempts among violent offenders and impulsive fire setters.
Psychobiological data on 58 violent offenders and impulsive fire setters were analyzed for associations with history of suicide attempts. Subjects with a history of suicide attempts serious enough to require an admission to a medical facility had significantly lower mean cerebrospinal fluid 5-hydroxyindoleacetic acid and 3-methoxy-4-hydroxyphenylglycol concentrations than subjects who had not made such attempts. A linear discriminant function analysis based on psychobiological and behavioral variables correctly classified 79% of the subjects according to the suicide attempt history positive and negative outcomes.
Virkkunen
M
M
Laboratory of Clinical Studies, DICBR, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD 20892.
De Jong
J
J
Bartko
J
J
Linnoila
M
M
D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D003417:Criminal Psychology; D007174:Disruptive, Impulse Control, and Conduct Disorders / Q000175:diagnosis*; D005391:Firesetting Behavior / Q000097:blood / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D005500:Follow-Up Studies; D006018:Glycols / Q000134:cerebrospinal fluid*; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000134:cerebrospinal fluid*; D007175:Impulsive Behavior / Q000097:blood / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D008297:Male; D008734:Methoxyhydroxyphenylglycol / Q000134:cerebrospinal fluid*; D011336:Probability; D013406:Suicide, Attempted / Q000523:psychology*; D014754:Violence
D001786:Blood Glucose; D006018:Glycols; D008734:Methoxyhydroxyphenylglycol; D006897:Hydroxyindoleacetic Acid