Immunohistochemical diagnosis of central nervous system tumours on smear preparations.
The successful application of immunostaining on smear preparations from 34 tumours of the central nervous system using the peroxidase-antiperoxidase technique and the avidin-biotin-peroxidase complex technique with commercially available antibodies is described. When combined with conventional smear preparations, the technique contributed to a rapid and accurate diagnosis in 79% of cases and is advocated to be a useful adjunct in neurosurgical diagnosis.
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Department of Morbid Anatomy, Chinese University of Hong Kong.
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D000941:Antigens / Q000276:immunology; D001254:Astrocytoma / Q000175:diagnosis / Q000276:immunology; D001706:Biopsy; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000276:immunology; D005904:Glial Fibrillary Acidic Protein / Q000276:immunology; D006801:Humans; D007150:Immunohistochemistry; D066298:In Vitro Techniques; D007633:Keratins / Q000276:immunology; D008562:Membrane Glycoproteins / Q000276:immunology; D008579:Meningioma / Q000175:diagnosis / Q000276:immunology; D018396:Mucin-1; D009418:S100 Proteins / Q000276:immunology; D013120:Spinal Cord Neoplasms / Q000175:diagnosis* / Q000276:immunology
D000941:Antigens; D005904:Glial Fibrillary Acidic Protein; D008562:Membrane Glycoproteins; D018396:Mucin-1; D009418:S100 Proteins; D007633:Keratins