Enhancement of chemical activation via radical-dependent mechanisms: an emerging concept in chemical-chemical interactions.
Trush
M A
MA
Department of Environmental Health Sciences, Johns Hopkins University, Baltimore, Maryland 21205.
Thompson
D C
DC
D000818:Animals; D001761:Bleomycin / Q000494:pharmacology*; D002083:Butylated Hydroxyanisole / Q000633:toxicity*; D002084:Butylated Hydroxytoluene / Q000633:toxicity*; D055598:Chemical Phenomena; D002621:Chemistry; D004247:DNA / Q000187:drug effects*; D004347:Drug Interactions; D005609:Free Radicals; D008168:Lung / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D008175:Lung Neoplasms / Q000378:metabolism; D008297:Male; D008546:Melanoma, Experimental / Q000378:metabolism; D051379:Mice; D008861:Microsomes / Q000378:metabolism*; D016685:Mitomycin; D008937:Mitomycins / Q000494:pharmacology*
D005609:Free Radicals; D008937:Mitomycins; D001761:Bleomycin; D002084:Butylated Hydroxytoluene; D002083:Butylated Hydroxyanisole; D016685:Mitomycin; D004247:DNA