[An experimental study of the water balance and acid-base state of the blood during infusions of the plasma substitute oksiamal].
The influence of the plasma substitute oxyamal on shifts in the water and acid-base balance of the blood was studied in experiments on dogs with simulated severe hemorrhagic shock. Oxyamal therapy of the severe hemorrhagic shock led to a stable reduction of the volume of circulating plasma and blood, and to a rapid normalization of blood circulation. No disorders were observed in the fluid distribution in the body, acid-base balance rapidly recovered that has evidenced a full-value transcapillary water-ion exchange.
Litvinenko
Iu A
IuA
Kolonina
I R
IR
Gorbunova
N A
NA
D000136:Acid-Base Equilibrium / Q000187:drug effects*; D000818:Animals; D003911:Dextrans / Q000008:administration & dosage; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D005260:Female; D006895:Hydroxyethyl Starch Derivatives / Q000008:administration & dosage*; D007262:Infusions, Intravenous; D008297:Male; D012771:Shock, Hemorrhagic / Q000097:blood / Q000628:therapy; D013213:Starch / Q000031:analogs & derivatives*; D013997:Time Factors; D014882:Water-Electrolyte Balance / Q000187:drug effects*
D003911:Dextrans; D006895:Hydroxyethyl Starch Derivatives; D013213:Starch
Eksperimental'noe izuchenie vodnogo balansa i kislotno-osnovnogo sostoianiia krovi pri infuziiakh plazmozamenitelia oksiamala.