[Protective properties of Vi-antigen preparations as dependent on their adhesin content].
Adhesins contained in the preparation of Vi-antigen have been found to enhance its immunogenic and protective properties. In the preparations of Vi-antigen obtained from Salmonella typhi and Citrobacter freundii the presence of two antigenic determinants has been revealed. One of them is associated with the Vi-receptor and the other determinant, with adhesin. Both determinants take part in the protection of mice from Salmonella infection.
Alliluev
A P
AP
Kotel'nikova
O V
OV
Korneeva
S A
SA
Fish
N G
NG
Kulinich
L I
LI
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D000942:Antigens, Bacterial / Q000276:immunology*; D001422:Bacterial Adhesion; D001426:Bacterial Proteins / Q000276:immunology*; D002954:Citrobacter / Q000276:immunology*; D004353:Drug Evaluation, Preclinical; D000939:Epitopes / Q000276:immunology; D007114:Immunization; D051379:Mice; D008806:Mice, Inbred AKR; D008808:Mice, Inbred CBA; D011135:Polysaccharides, Bacterial; D012481:Salmonella Infections, Animal / Q000517:prevention & control; D012485:Salmonella typhi / Q000276:immunology* / Q000472:pathogenicity; D012486:Salmonella typhimurium / Q000472:pathogenicity; D013329:Structure-Activity Relationship; D014774:Virulence
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D000939:Epitopes; D011135:Polysaccharides, Bacterial
Protektivnye svoĭstva preparatov Vi-antigena v zavisimosti ot soderzhaniia v nikh adgezina.