Evidence for a highly nuclease resistant RNA fragment in prosomes.
Prosomes, small cytoplasmic particles of mouse erythroblasts were found to contain low molecular weight RNA molecules in the range of 80 nucleotides. Nuclease digestion of prosomes suggests that prosomal proteins cover and protect almost the whole length of their RNA(s). Our results demonstrate clearly that RNA is an intrinsic component of prosomes.
Dineva
B
B
Biologisches Institut, Universität Stuttgart, FRG.
Tomek
W
W
Köhler
K
K
Schmid
H P
HP
D000818:Animals; D003593:Cytoplasm / Q000032:analysis; D004591:Electrophoresis, Polyacrylamide Gel; D004900:Erythroblasts / Q000032:analysis; D051379:Mice; D008807:Mice, Inbred BALB C; D012313:RNA / Q000032:analysis*; D012260:Ribonucleases; D012261:Ribonucleoproteins / Q000032:analysis*
D012261:Ribonucleoproteins; D012313:RNA; D012260:Ribonucleases