Treatment of apocrine chromhidrosis with topical capsaicin.
A 30-year-old white woman with facial apocrine chromhidrosis was treated successfully with topical capsaicin once or twice daily. Paired comparison of treated versus untreated sides and active drug-treated versus vehicle-treated sides showed suppression of the chromhidrosis only when capsaicin was used. After treatment was discontinued, the chromhidrosis returned within 2 days.
Marks
J G
JG
Division of Dermatology, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey 17033.
D000287:Administration, Topical; D000328:Adult; D000367:Age Factors; D001050:Apocrine Glands; D002211:Capsaicin / Q000008:administration & dosage / Q000627:therapeutic use*; D005145:Face; D005260:Female; D006801:Humans; D008062:Lipofuscin / Q000032:analysis; D010859:Pigmentation Disorders / Q000188:drug therapy; D013373:Substance P / Q000032:analysis; D013543:Sweat Gland Diseases / Q000188:drug therapy; D013545:Sweat Glands
D008062:Lipofuscin; D013373:Substance P; D002211:Capsaicin