Osteoclast-type giant cell neoplasms of the parotid gland.
The parotid gland is added to the list of parenchymal organs, notably the pancreas, in which osteoclast-like cells appear as constituent cells in their neoplasms. The cells' role in the neoplasms is a reactive one or, more rarely, as an integral element in an osteoclast-type giant cell neoplasm or so-called osteoclastoma. Distinctive in histological appearance, the osteoclast-type giant cell neoplasm is a malignant lesion that, to date, has been described only in the pancreas and parotid glands. This report presents examples of each type of giant cell lesion in the parotid gland.
Batsakis
J G
JG
Department of Pathology, University of Texas M.D. Anderson Hospital and Tumor Institute, Houston.
Ordonez
N G
NG
Sevidal
P A
PA
Baker
J R
JR
D000368:Aged; D000369:Aged, 80 and over; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology*; D005870:Giant Cell Tumors / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000473:pathology*; D013194:Staining and Labeling