Antigenic and biological properties of Rift Valley fever virus isolated during the 1987 Mauritanian epidemic.
The antigenic and biological properties of three strains of Rift Valley fever virus (RVFV) isolated during the 1987 epidemic in Mauritania were compared with those of strains isolated previously in West Africa and with other selected African strains. Neither the antigenic characteristics of the Mauritanian isolates, as monitored by the binding of 59 monoclonal antibodies, nor the electrophoretic migration of the virus-specific structural and non-structural proteins were significantly different from other strains of RVFV isolated in this region or elsewhere in sub-Saharan Africa. Biological and antigenic traits which distinguished the strains isolated from the 1977 Egyptian epidemic were not associated with the Mauritanian isolates.
Saluzzo
J F
JF
United States Army Medical Research, Institute of Infectious Diseases, Fort Detrick, Frederick, MD.
Anderson
G W
GW
Hodgson
L A
LA
Digoutte
J P
JP
Smith
J F
JF
D000818:Animals; D000911:Antibodies, Monoclonal; D002043:Bunyaviridae / Q000276:immunology*; D002478:Cells, Cultured; D004196:Disease Outbreaks; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D007372:Interferons / Q000494:pharmacology; D008435:Mauritania; D011233:Precipitin Tests; D051381:Rats; D011920:Rats, Inbred WF; D012295:Rift Valley Fever / Q000453:epidemiology* / Q000382:microbiology; D012296:Rift Valley fever virus / Q000276:immunology* / Q000302:isolation & purification / Q000502:physiology; D013045:Species Specificity; D010948:Viral Plaque Assay; D014764:Viral Proteins / Q000032:analysis
D000911:Antibodies, Monoclonal; D014764:Viral Proteins; D007372:Interferons