[A case of familial congenital analgesia with autosome-dominant type of inheritance].
Inborn analgesia (IA) is described in 3 members of a family: a 14 month-old girl, hel father and grandfather on the paternal line. Generalized indifference to pain and visceral analgesia with other senses intact was noted in all patients since birth. Profound reflexes, intellectual development, karyotype, motor and sensory nervous excitation propagation velocities, somatosensory evoked potentials were all normal. Notedly, the IA inheritance was found to be autosome-dominant in this family.
Aver'ianov
Iu N
IuN
Nechkina
N P
NP
Vinogradova
N V
NV
Zakhidov
A Ia
AIa
D000328:Adult; D002869:Chromosome Aberrations / Q000209:etiology / Q000235:genetics*; D025063:Chromosome Disorders; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D007223:Infant; D008297:Male; D000699:Pain Insensitivity, Congenital / Q000209:etiology / Q000235:genetics*
Semeĭnyĭ sluchaĭ vrozhdennoĭ anal'gezii s autosomno-dominantnym tipom nasledovaniia.