[Dynamic changes in the hemostatic indices of diabetics during biostator control].
In 25 patients with insulin-dependent diabetes and without microangiopathic complications the main hemostatic inhibitors antithrombin III, alpha-2-macroglobulin, and alpha-2-antiplasmin were examined before and after an optimal compensation of the carbohydrate metabolism was achieved. The patients were treated for 24 hours with the help of an artificial endocrine pancreas--biostator. The initial mean value of hyperglycemia of 15.61 mmol/l fell significantly to a mean value of 5.67 mmol/l at the end of the 24 hour treatment. During this 24 hour period the levels of the indices followed up did not change significantly. They were as follows: antithrombin III--98.48%, alpha-2-macroglobulin--112.25%, alpha-2-antiplasmin--110.68%. The lack of changes in the hemostatic inhibitors is explained by the short term biostator treatment.
Petkova
M
M
Kamenov
V
V
Tsanev
A
A
D000293:Adolescent; D000328:Adult; D000990:Antithrombin III / Q000032:analysis; D001786:Blood Glucose / Q000032:analysis; D002908:Chronic Disease; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000188:drug therapy; D005341:Fibrinolysin / Q000032:analysis; D006487:Hemostasis / Q000502:physiology*; D006801:Humans; D007332:Insulin Infusion Systems; D013997:Time Factors; D000979:alpha-2-Antiplasmin / Q000032:analysis; D000511:alpha-Macroglobulins / Q000032:analysis
D001786:Blood Glucose; D000979:alpha-2-Antiplasmin; D000511:alpha-Macroglobulins; C024668:plasmin-alpha(2)-macroglobulin complex; D000990:Antithrombin III; D005341:Fibrinolysin
Dinamichni promeni na niakoi pokazateli na khemostazata pri diabetitsi po vreme na biostatoren kontrol.