Basal cell carcinoma with hyaline inclusions.
A 67-year-old woman had a basal cell carcinoma of the forehead containing numerous hyaline cytoplasmic inclusions. Electron microscopic studies revealed that these inclusions were aggregates of cytoplasmic filaments. Immunohistochemical studies demonstrated reactivity for keratin, vimentin, and smooth-muscle myosin in these structures. Because of potential diagnostic difficulties, the pathologist should be aware of this unusual form of basal cell carcinoma.
Sahin
A A
AA
Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston 77030.
Ro
J Y
JY
Grignon
D J
DJ
Ordóñez
N G
NG
D000368:Aged; D002280:Basal Cell Carcinoma / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D006818:Hyalin / Q000473:pathology*; D002479:Inclusion Bodies / Q000473:pathology* / Q000648:ultrastructure; D007382:Intermediate Filaments / Q000473:pathology / Q000648:ultrastructure; D007633:Keratins / Q000032:analysis; D009364:Neoplasm Recurrence, Local; D012878:Skin Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D013194:Staining and Labeling
D007633:Keratins