UMC, another Cromer-related blood group antigen.
An antibody found in the serum of a Japanese blood donor detects a new high-frequency red cell antigen named UMC. UMC is absent from Inab phenotype cells, weakly expressed on Dr(a-) cells, and destroyed by alpha-chymotrypsin but not trypsin treatment of red cells. UMC is, therefore, a Cromer-related antigen. Immunoblotting with anti-UMC showed that UMC antigen, in common with other Cromer-related antigens, is carried on a red cell surface glycoprotein with an apparent molecular weight of 70,000, which presumably is the complement regulatory protein decay-accelerating factor.
Daniels
G L
GL
Medical Research Council Blood Group Unit, London, UK.
Okubo
Y
Y
Yamaguchi
H
H
Seno
T
T
Ikuta
M
M
D000328:Adult; D001789:Blood Group Antigens / Q000235:genetics; D015153:Blotting, Western; D018958:CD55 Antigens; D004910:Erythrocyte Membrane / Q000276:immunology*; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D008562:Membrane Glycoproteins / Q000276:immunology*; D008565:Membrane Proteins / Q000276:immunology*; D008970:Molecular Weight; D010375:Pedigree
D001789:Blood Group Antigens; D018958:CD55 Antigens; D008562:Membrane Glycoproteins; D008565:Membrane Proteins