title: Alpha-fetoprotein and mediastinal germ cell tumors.
abstract: The Authors discuss the utility of alpha-fetoprotein (AFP) determination in mediastinal dysembryomas. AFP should be determined in all cases of mediastinal lesion. High levels of up to 500 ng/ml are a sure sign of germ cell tumors. An extremely high level (greater than 1,000 ng/ml) is an indication that the lesion is a mesoblastoma. An increase in the AFP level in the follow-up of patients affected by germ cell tumors is a sure sign of the recurrence of the disease.
authors: M
authors: M
authors: Rapellino
authors: A
authors: A
authors: Cellerino
authors: F
authors: F
authors: Ardissone
authors: D
authors: D
authors: Libertucci
authors: F
authors: F
authors: Coni
authors: G
authors: G
authors: Aimo
authors: F
authors: F
authors: Pecchio
mesh_terms: D006801:Humans; D008479:Mediastinal Neoplasms / Q000175:diagnosis*; D009373:Neoplasms, Germ Cell and Embryonal / Q000175:diagnosis*; D013724:Teratoma / Q000175:diagnosis*; D000509:alpha-Fetoproteins / Q000032:analysis*
chemical_list: D000509:alpha-Fetoproteins