[Age-related characteristics of RNA transport through the nuclear membrane].
The effect of cytosol and ATP-regenerating system on RNA, transport was studied in isolated liver nuclei of adult and old rats. The stimulating effect of cytosol was found not to depend on the age of animals. The release of RNA from old rat liver nuclei activated by the ATP-regenerating system was more expressed compared to adult rats. It is assumed that the age changes of energy-delivering system of the RNA transport through nuclear membrane may be conditioned by the deficit of endogenous energetic substrates in the hepatic cells of old animals.
Mozzhukhina
T G
TG
Litoshenko
A Ia
AIa
D000255:Adenosine Triphosphate / Q000494:pharmacology; D000367:Age Factors; D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism; D003593:Cytoplasm / Q000378:metabolism; D003600:Cytosol; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism; D009685:Nuclear Envelope / Q000378:metabolism*; D012313:RNA / Q000187:drug effects / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013053:Spectrophotometry
D012313:RNA; D000255:Adenosine Triphosphate
Vozrastnye osobennosti transporta RNK cherez iadernuiu obolochku.