[Antihistaminic or anti-degranulating activity of pregnancy serum].
From observation of women who had anaphylactic accidents to hymenoptera venoms, with positive histamine release, we have noticed that these same patients lose their histamine release during pregnancy. Measurement of histamine release to pollens confirms the existence of a histaminase, which develops from the third month of the pregnancy and which is the origin of the loss of histamine release. This study makes eliminates a possible anti-degranulation ability of pregnancy sera.
Sabbah
A
A
Laboratoire d'Immuno-Allergologie CHU, Angers.
Heulin
M G
MG
Drouet
M
M
Bonneau
J C
JC
Sellin
J L
JL
Bouquin
D
D
D006631:Amine Oxidase (Copper-Containing) / Q000097:blood; D001491:Basophils / Q000276:immunology*; D003594:Cytoplasmic Granules / Q000276:immunology*; D005260:Female; D006633:Histamine Antagonists / Q000097:blood*; D006636:Histamine Release; D006801:Humans; D011247:Pregnancy / Q000276:immunology*; D011852:Radioallergosorbent Test; D012882:Skin Tests
D006633:Histamine Antagonists; D006631:Amine Oxidase (Copper-Containing)
Activité anti-histaminique ou anti-dégranulante de sérum de grossesse.