Intracranial stimulation of facial nerve in humans with the magnetic coil.
Using ourselves as subjects, maximal compound motor action potentials (CMAPs) were evoked in ipsilateral nasal and orbicularis oculi muscles (onset latency 4.9-5.4 msec) by a magnetic coil (MC) tangentially oriented over parieto-occipital scalp. The facial nerve was also electrically stimulated sequentially at the posterior tragus near the stylomastoid foramen, anterior tragus and 3 cm more distally. Onset latency of the CMAP elicited at posterior tragus ranged from 1.0 to 1.3 msec less than that elicited by the MC over scalp. Because the measured distal facial nerve motor conduction velocity was 50-60 m/sec, the locus of impulse generation induced by magnetic coil stimulation was estimated to be approximately 6.5 cm proximal to the site of electrical stimulation at the posterior tragus, i.e., closer to the exit of the facial nerve from the brain-stem than to its entrance into the internal auditory meatus. This non-invasive technique should be useful in evaluating patients with peripheral facial nerve disorders including Bell's palsy.
Maccabee
P J
PJ
Department of Neurology, State University of New York, Brooklyn 11203.
Amassian
V E
VE
Cracco
R Q
RQ
Cracco
J B
JB
Anziska
B J
BJ
D000200:Action Potentials; D000328:Adult; D004558:Electric Stimulation; D005154:Facial Nerve / Q000502:physiology*; D006801:Humans; D008280:Magnetics; D008875:Middle Aged; D009132:Muscles / Q000502:physiology