[Effect of a limitation of the food ration on macrophage functional activity and angiogenesis in mice with metastasizing tumors].
In mice with metastasizing tumors that received a reduced (by 30-40%) daily ration, suppression of neovascularization processes and normalization of macrophage function were recorded: activity of macrophages in the area of the metastatic growth increased, while activity of macrophages suppressing T-lymphocytes in the spleen was decreased. It has been suggested that these effects play a role in the phenomenon observed by the authors--suppression of the metastatic processes in the test mice kept on a reduced food ration.
Sopotsinskaia
E B
EB
Umanskiĭ
V Iu
VIu
Lisniak
I A
IA
D000818:Animals; D005260:Female; D007108:Immune Tolerance; D007113:Immunity, Innate; D008175:Lung Neoplasms / Q000178:diet therapy* / Q000276:immunology / Q000556:secondary; D008264:Macrophages / Q000201:enzymology / Q000276:immunology*; D051379:Mice; D008810:Mice, Inbred C57BL; D009368:Neoplasm Transplantation; D009389:Neovascularization, Pathologic; D011650:Pulmonary Alveoli / Q000276:immunology; D012867:Skin / Q000098:blood supply; D013154:Spleen / Q000276:immunology
Vliianie ogranicheniia pishchevogo ratsiona na funktsional'nuiu aktivnost' makrofagov i angiogenez u mysheĭ s metastaziruiushchimi opukholiami.