title: False-negative amniotic fluid acetylcholinesterase in a case of meningo-encephalocele.
abstract: We describe a patient with a significantly elevated serum alphafetoprotein (AFP) concentration at 17 weeks of gestation, who showed only a marginally increased amniotic fluid AFP and lacked the second rapidly migrating band of acetylcholinesterase electrophoresis. Ultrasound examination revealed an encephalocele and ventriculomegaly. Autopsy showed that the encephalocele was not covered by skin.
authors: Department of Obstetrics and Gynaecology, University Hospital Groningen, The Netherlands.
authors: A
authors: A
authors: Boogert
authors: J G
authors: JG
authors: Aarnoudse
authors: H W
authors: HW
authors: De Bruijn
authors: A
authors: A
authors: Gouw
mesh_terms: D000110:Acetylcholinesterase / Q000032:analysis*; D000328:Adult; D000653:Amniotic Fluid / Q000201:enzymology*; D004591:Electrophoresis, Polyacrylamide Gel; D004677:Encephalocele / Q000175:diagnosis*; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D008588:Meningocele / Q000175:diagnosis*; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014463:Ultrasonography; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D000509:alpha-Fetoproteins; D000110:Acetylcholinesterase