Substance P-like immunoreactive neurons in the arcuate nucleus project to the median eminence in rat.
Substance P-containing nerve fibers in the median eminence of rat arise in cells located in the arcuate nucleus. Two days following surgical lesioning of the median eminence immunoreactive substance P accumulated in neuronal perikarya in the middle part (rostrocaudally) of the arcuate nucleus, mainly in its ventromedial portion. Substance P-immunostained cells appeared nowhere else in the hypothalamus following surgical lesion of the median eminence while they were found in several hypothalamic and extrahypothalamic cell groups after colchicine treatment.
Palkovits
M
M
First Department of Anatomy, Semmelweis University Medical School, Budapest, Hungary.
Kakucska
I
I
Makara
G B
GB
D000818:Animals; D001111:Arcuate Nucleus of Hypothalamus / Q000166:cytology / Q000378:metabolism*; D007150:Immunohistochemistry; D008297:Male; D008473:Median Eminence / Q000166:cytology*; D051381:Rats; D013373:Substance P / Q000378:metabolism*
D013373:Substance P