title: Substance P and hydra: an immunohistochemical and physiological study.
abstract: 1. The distribution of substance P-like immunoreactivity was studied in Hydra attenuata using the peroxidase-antiperoxidase technique. 2. Positive immunoreactivity was observed in ectodermal nerve cells and fibers as well as in nematoblasts at various stages of differentiation. 3. Administration of synthetic substance P to regenerating hydra did not affect regeneration rates. Exogenous substance P administration stimulated tentacle contraction and nematocyst displacement within battery cells. 4. It is suggested that substance P acts on the contractile apparatus of Hydra tissues.
authors: Istituto Cibernetica C.N.R., Napoli, Italy.
authors: P
authors: P
authors: Pierobon
authors: M
authors: M
authors: Kemali
authors: N
authors: N
authors: Milici
mesh_terms: D000818:Animals; D006829:Hydra; D009474:Neurons / Q000166:cytology / Q000378:metabolism; D012038:Regeneration / Q000187:drug effects; D013373:Substance P / Q000378:metabolism* / Q000494:pharmacology
chemical_list: D013373:Substance P