title: [A quantitative method of determining middle molecule peptides in the blood serum of patients with chronic renal insufficiency].
abstract: Gel chromatography and high performance liquid chromatography have been applied to analysis of the blood serum peptides in renal patients. The levels of the peptides with a molecular mass of 300-5000 D have been found to correlate with the severity of the kidney involvement. A rapid method for measuring the concentrations of these peptides has been developed, based on the precipitation of the blood serum high-molecular peptides followed by measurement of the concentration of the peptides remaining in the supernatant with the use of a specific reagent. The suggested method has been used to define the severity of the kidney involvement and to monitor the efficacy of hemodialysis and hemoperfusion.
authors: N N
authors: NN
authors: Salikhova
authors: R I
authors: RI
authors: Akhmedzhanov
authors: Sh G
authors: ShG
authors: Mukhamadieva
authors: A D
authors: AD
authors: Sakhibov
mesh_terms: D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood*; D010455:Peptides / Q000097:blood*
chemical_list: D010455:Peptides
vernacular_title: Kolichestvennyĭ metod opredeleniia srednemolekuliarnykh peptidov v syvorotke krovi bol'nykh s khronicheskoĭ pochechnoĭ nedostatochnost'iu.