[Evaluation of the interferon status of human subjects by whole-blood specimens].
A simple method for the determination of three parameters of human interferon status: serum interferon (IFN) and induction of alpha- and gamma-IFN in specimens of 10-fold-diluted whole blood in a volume of 200 microliters is described. Standard parameters of interferon status of normal subjects in the whole blood are given which can be visually presented as a triangle of interferon status, and its deviations in various pathological conditions. The whole-blood method is recommended for large-scale clinical surveys, especially in pediatrics.
Grigorian
S S
SS
Maĭorov
I A
IA
Ivanova
A M
AM
Ershov
F I
FI
D001681:Biological Assay / Q000379:methods; D002478:Cells, Cultured; D006801:Humans; D007369:Interferon Inducers / Q000494:pharmacology; D007370:Interferon Type I / Q000097:blood; D007371:Interferon-gamma / Q000097:blood; D007372:Interferons / Q000097:blood*; D008214:Lymphocytes / Q000276:immunology; D009522:Newcastle disease virus; D010835:Phytohemagglutinins / Q000494:pharmacology; D014721:Vesicular stomatitis Indiana virus
D007369:Interferon Inducers; D007370:Interferon Type I; D010835:Phytohemagglutinins; C028784:phytohemagglutinin-P; D007371:Interferon-gamma; D007372:Interferons
Otsenka interferonovogo statusa liudeĭ po probam tsel'noĭ krovi.