Membrane channel blockers impair cell coupling in the rabbit sinus node strips.
Barium ions, (-) verapamil or tetrodotoxin added to the sucrose gap increased the longitudinal internal resistance in the rabbit sinus node strips. The possible mechanism of these effects are discussed.
Tuganowski
W
W
Department of Physiology, Silesian Medical Academy, Katowice, Poland.
Bukowski
M
M
D000818:Animals; D001464:Barium / Q000494:pharmacology; D017609:Barium Compounds; D002712:Chlorides; D004594:Electrophysiology; D066298:In Vitro Techniques; D007473:Ion Channels / Q000187:drug effects*; D008566:Membranes / Q000378:metabolism; D011817:Rabbits; D012849:Sinoatrial Node / Q000166:cytology* / Q000187:drug effects; D013779:Tetrodotoxin / Q000494:pharmacology; D014700:Verapamil / Q000494:pharmacology
D017609:Barium Compounds; D002712:Chlorides; D007473:Ion Channels; C024986:barium chloride; D001464:Barium; D013779:Tetrodotoxin; D014700:Verapamil