[Comparative studies of bronchial secretions in children with chronic, nontuberculous lung diseases. 3. The detection of lysozyme, transferrin, alpha 1-antitrypsin, alpha 2-macroglobulin, haptoglobin and alpha 1-acid glycoprotein].
In 166 bronchial secretions from 63 children with chronic nontuberculous lung diseases lysozyme, transferrin, alpha 1-antitrypsin, alpha 2-macroglobulin, haptoglobin and alpha 1-acid glycoprotein were estimated. In patients with hard bronchoscopic or bronchographic alterations a reduction of lysozyme, alpha 1-antitrypsin and alpha 2-macroglobulin could be found. These proteins were measured more frequently in cases with dark altered mucosa. Moreover no relation could be found between transferrin, alpha 1-antitrypsin and alpha 2-macroglobulin and the outbreak of the diseases. -In bacterial contaminated secretions transferrin could be demonstrated more frequently in comparison with sterile bronchial secretions.
Stelzner
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A
Zentralinstitut für Mikrobiologie und experimentelle Therapie der AdW der DDR, Jena.
Groh
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A
Lehnert
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U
D000293:Adolescent; D001980:Bronchi / Q000032:analysis* / Q000201:enzymology / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D006242:Haptoglobins / Q000032:analysis; D006801:Humans; D008171:Lung Diseases / Q000378:metabolism*; D009113:Muramidase / Q000032:analysis; D009961:Orosomucoid / Q000032:analysis; D011506:Proteins / Q000032:analysis*; D014168:Transferrin / Q000032:analysis; D000515:alpha 1-Antitrypsin / Q000032:analysis; D000511:alpha-Macroglobulins / Q000032:analysis
D006242:Haptoglobins; D009961:Orosomucoid; D011506:Proteins; D014168:Transferrin; D000515:alpha 1-Antitrypsin; D000511:alpha-Macroglobulins; D009113:Muramidase
Vergleichende Bronchialsekretuntersuchungen bei Kindern mit chronischen, nichttuberkulösen Lungenerkrankungen. 3. Mitteilung: Zum Nachweis von Lysozym, Transferrin, Alpha 1-Antitrypsin, Alpha 2-Makroglobulin, Haptoglobin, Alpha 1-saures Glykoprotein.