Bactericidal activity of human sera with a physiologic or genetic defect of the complement system.
The serum of patient suffering genetically conditioned C2 defect showed a weak bactericidal activity against Pseudomonas aeruginosa strains. Out of 23 tested strains one was susceptible comparing with 16 ones sensitive to normal human serum. The normal cord serum exerted a bactericidal effect on 8 strains. All sera were found to be active against Salmonella strains tested.
Jankowski
S
S
Department of Microbiology, Wrocław, Poland.
Grzybek-Hryncewicz
K
K
Kopeć
W
W
Zalewski
J
J
Zielinsk
S A
SA
D001770:Blood Bactericidal Activity; D003175:Complement C2 / Q000172:deficiency / Q000235:genetics; D003165:Complement System Proteins / Q000172:deficiency / Q000235:genetics*; D003967:Diarrhea / Q000382:microbiology; D005312:Fetal Blood / Q000276:immunology; D006801:Humans; D007231:Infant, Newborn; D011552:Pseudomonas Infections / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000276:immunology*; D012475:Salmonella / Q000276:immunology*; D012480:Salmonella Infections / Q000382:microbiology; D012477:Salmonella enteritidis / Q000276:immunology; D012486:Salmonella typhimurium / Q000276:immunology; D014552:Urinary Tract Infections / Q000382:microbiology
D003175:Complement C2; D003165:Complement System Proteins