[Evaluation of the therapeutic effect of flumazenil in hepatic encephalopathy using cerebral cartography].
We investigated the therapeutic effect of flumanezil on acute and chronic hepatic encephalopathy in a group of cirrhotics; its efficacy was evaluated using clinical data and neurophysiologic examination, e.g. brain mapping. Flumazenil was not found to induce significant changes in the clinical status or in maps of the cerebral activity of patients with chronic encephalopathy. In acute encephalopathy, flumazenil improved clinical status, as was confirmed neurophysiologically by improved cerebral activity on brain mapping.
Bello Mimbrera
G
G
García de León
M
M
de la Torre Gutiérrez
S
S
Montero Vázquez
J
J
Torres Salcines
J
J
de la Torre Fernández
J M
JM
D000208:Acute Disease; D000368:Aged; D001931:Brain Mapping; D002908:Chronic Disease; D004341:Drug Evaluation; D005260:Female; D005442:Flumazenil / Q000627:therapeutic use*; D006501:Hepatic Encephalopathy / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications; D008297:Male; D008875:Middle Aged
D005442:Flumazenil
Evaluación del efecto terapéutico del flumazenil en la encefalopatía hepática mediante cartografía cerebral.