Aggravation of diabetic nephropathy by lithium: a case report and review of the literature.
A manic-depressive diabetic man receiving lithium carbonate therapy had massive proteinuria, which dramatically improved after the withdrawal of lithium. The authors discuss previous cases of lithium-induced nephrotic syndrome in nondiabetics and draw attention to the possibility that lithium therapy aggravates protein excretion in diabetic patients.
Pawel
B R
BR
Department of Medicine, Joslin Diabetes Center, Boston.
Kaye
W A
WA
Khan
M Y
MY
Fergusen
B D
BD
Federman
M
M
Crosson
A W
AW
D000208:Acute Disease; D001714:Bipolar Disorder / Q000188:drug therapy; D003928:Diabetic Nephropathies / Q000139:chemically induced*; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D008094:Lithium / Q000009:adverse effects*; D016651:Lithium Carbonate; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000139:chemically induced* / Q000473:pathology
D016651:Lithium Carbonate; D008094:Lithium