title: Identification of drug interactions by meta-analysis of premarketing trials: the effect of smoking on the pharmacokinetics and dosage requirements for flecainide acetate.
authors.affiliation: Medical Service, Veterans Affairs Medical Center, Minneapolis, MN 55417.
authors.forename: J L
authors.initials: JL
authors.lastname: Holtzman
authors.forename: C E
authors.initials: CE
authors.lastname: Weeks
authors.forename: D C
authors.initials: DC
authors.lastname: Kvam
authors.forename: D A
authors.initials: DA
authors.lastname: Berry
authors.forename: L
authors.initials: L
authors.lastname: Mottonen
authors.forename: B P
authors.initials: BP
authors.lastname: Ekholm
authors.forename: S F
authors.initials: SF
authors.lastname: Chang
authors.forename: G J
authors.initials: GJ
authors.lastname: Conard
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D005260:Female; D005424:Flecainide / Q000008:administration & dosage / Q000493:pharmacokinetics*; D006331:Heart Diseases / Q000188:drug therapy*; D006801:Humans; D008297:Male; D015201:Meta-Analysis as Topic; D008875:Middle Aged; D012907:Smoking / Q000378:metabolism*
chemical_list: D005424:Flecainide