title: The significance of Pseudomonas aeruginosa in chronic otitis media.
abstract: Fifteen patients with chronic otitis media, where the organism cultured was Pseudomonas aeruginosa, had previously been treated with a variety of antibiotics, ear drops and surgical procedures. In 8 patients the discharge persisted. Between October 1986 and August 1987 these patients were treated with a combination of antibiotics (including piperacillin, ceftriaxone, amikacin and tobramycin) specific for Pseudomonas administered intravenously. In 7 patients the infection cleared completely. Follow-up ranged from 1 month to 1 year (average 4.5 months). The regimen described could be of value in patients who do not respond to standard methods of treatment.
authors.affiliation: Department of Otorhinolaryngology, University of Pretoria.
authors.forename: D L
authors.initials: DL
authors.lastname: Stolp
authors.forename: J G
authors.initials: JG
authors.lastname: Swart
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D006801:Humans; D008875:Middle Aged; D010033:Otitis Media / Q000382:microbiology*; D010035:Otitis Media, Suppurative / Q000188:drug therapy / Q000382:microbiology*; D011552:Pseudomonas Infections / Q000188:drug therapy; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents