The promoter region of the Drosophila alpha 2-tubulin gene directs testicular and neural specific expression.
The temporal and spatial expression pattern of the Drosophila melanogaster alpha 2-tubulin gene (alpha 2) has been investigated by examining the expression of an alpha 2-lacZ fusion gene. When this fusion gene is introduced into the germ line by P-element mediated transformation, expression is only detected in chordotonal organs and testes. Chordotonal organs, which are sensory organs of the peripheral nervous system, express the gene from late embryonic through adult stages in both males and females. Testicular expression occurs from larval through adult stages and is limited to germ-line cells, the primary and secondary spermatocytes and perhaps the early spermatids.
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Department of Biology, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts 02254-9110.
Wensink
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PC
D000818:Animals; D003001:Cloning, Molecular; D004331:Drosophila melanogaster / Q000196:embryology* / Q000235:genetics; D004625:Embryo, Nonmammalian / Q000166:cytology / Q000502:physiology; D005786:Gene Expression Regulation; D005796:Genes; D007814:Larva; D008297:Male; D009420:Nervous System / Q000196:embryology; D011401:Promoter Regions, Genetic; D011679:Pupa; D013737:Testis / Q000196:embryology; D014404:Tubulin / Q000235:genetics*; D001616:beta-Galactosidase / Q000235:genetics
D014404:Tubulin; D001616:beta-Galactosidase