[The induction and elimination of cytogenetic disorders in monkey lymphocytes following thiophosphamide action].
The dynamics of sister chromatid exchanges and chromosome aberrations in lymphocyte of monkey has been investigated after a thiophosphamide exposure. The process of induction and elimination of cytogenetic damages was described by the mathematical model. Developing the model in detail will allow to make a cytogenetic prognosis of remote consequences of mutagenic exposure.
Kuzin
S M
SM
Stukalov
S V
SV
Viktorov
V V
VV
Dzhemilev
Z A
ZA
Popandopulo
P G
PG
D000818:Animals; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D008214:Lymphocytes / Q000187:drug effects* / Q000648:ultrastructure; D008253:Macaca mulatta; D008297:Male; D008433:Mathematics; D008957:Models, Genetic; D012854:Sister Chromatid Exchange / Q000187:drug effects; D013852:Thiotepa / Q000633:toxicity*; D013997:Time Factors
D013852:Thiotepa
Induktsiia i éliminatsiia tsitogeneticheskikh narusheniĭ v limfotsitakh obez'ian posle vozdeĭstviia tiofosfamidom.