Efficacy of alternative tests for delayed-cyclic food hypersensitivity.
With the oral challenge food test (OCFT) used as the standard for delayed-cyclic food hypersensitivity diagnosis, blinded comparison studies were accomplished with 175 in vitro food specific IgE and 180 IgG radioallergosorbent tests, 180 food enzyme-linked immune complex assays, and 155 in vivo Multi-Test prick tests. The study was multi-centered, eight physicians and 37 patients participating. All of the compared tests were shown to be approximately 50% efficient when compared with the OCFT results, and, thus, nonefficacious.
King
W P
WP
Department of Otolaryngology and Communicative Sciences, Baylor College of Medicine, Waco, Texas.
Rubin
W
W
Fadal
R G
RG
Ward
W A
WA
Trevino
R J
RJ
Pierce
W B
WB
Stewart
A
A
Boyles
J H
JH
D004311:Double-Blind Method; D004797:Enzyme-Linked Immunosorbent Assay; D005502:Food; D005512:Food Hypersensitivity / Q000175:diagnosis*; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000175:diagnosis; D015337:Multicenter Studies as Topic; D011852:Radioallergosorbent Test; D012882:Skin Tests