title: Primary wound closure in haemophiliacs undergoing dental extractions.
abstract: 215 teeth were extracted in 62 haemophiliacs following a single infusion of factor VIII supplemented with antifibrinolytics. Tooth sockets were packed with Sorbacel gauze soaked with an antifibrinolytic. 1 group was sutured and the other left open. Primary closure of the extraction wound did not show direct effect on haemostasis. However, the size of the clot showed a statistically significant difference between the primary closure and open wound groups. The authors conclude that primary closure of the extraction wound protects the blood clot, makes the postoperative period more comfortable for patients and may subsequently decrease the risk of postoperative bleeding.
authors.affiliation: Oral Surgery Clinic, Faculty of Stomatology, University of Belgrade, Yugoslavia.
authors.forename: Z
authors.initials: Z
authors.lastname: Stajcić
authors.forename: R
authors.initials: R
authors.lastname: Baklaja
authors.forename: I
authors.initials: I
authors.lastname: Elezović
authors.forename: Z
authors.initials: Z
authors.lastname: Rolović
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D015119:Aminocaproic Acid / Q000008:administration & dosage; D001458:Bandages; D001777:Blood Coagulation; D002648:Child; D005169:Factor VIII / Q000008:administration & dosage; D006467:Hemophilia A; D006488:Hemostasis, Surgical / Q000379:methods*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D006472:Oral Hemorrhage / Q000517:prevention & control; D010149:Postoperative Pain / Q000517:prevention & control; D013537:Sutures; D014081:Tooth Extraction / Q000379:methods
chemical_list: D005169:Factor VIII; D015119:Aminocaproic Acid