Comparison of the polymorphic modifications of famotidine.
The polymorphic modifications of famotidine are described and characterized by their spectroscopic (infrared, X-ray) and some physico-chemical data. In addition to the standard physico-chemical data (melting point, solubility, bulk density) some further properties influencing its use in pharmaceutical technology are also characterized. The methods used to prepare the morphologically homogeneous modifications are also given.
Hegedüs
B
B
Gedeon Richter Ltd, Budapest, Hungary.
Bod
P
P
Harsányi
K
K
Péter
I
I
Kálmán
A
A
Párkányi
L
L
D002152:Calorimetry, Differential Scanning; D004355:Drug Stability; D015738:Famotidine / Q000737:chemistry*; D008958:Models, Molecular; D013055:Spectrophotometry, Infrared; D013816:Thermodynamics; D014961:X-Ray Diffraction
D015738:Famotidine