Serological specificity of Mycobacterium tuberculosis glycolipids.
Six glycolipid fractions can be extracted from lipid crude extracts of Canetti type strains of M. tuberculosis. Among these fractions are two phenolglycolipids. The major component is a triglycosyl phenolphthiocerol dimycocerosate (PGL-Tb 1) and the second is a monoglycosyl diacyl phenolphthiocerol identical to mycoside B of M. bovis. Similar glycolipid compounds can also be found in wild strains of M. tuberculosis recently isolated from tuberculous patients. One of these compounds has been identified as PGL-Tb 1.
Papa
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F
Unité de la Tuberculose et des Mycobactéries, Institut Pasteur, Paris, France.
Laszlo
A
A
David
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HL
Daffé
M
M
D000907:Antibodies, Bacterial; D000918:Antibody Specificity; D000942:Antigens, Bacterial / Q000302:isolation & purification*; D004797:Enzyme-Linked Immunosorbent Assay; D006017:Glycolipids / Q000276:immunology* / Q000302:isolation & purification; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000276:immunology*; D012698:Serologic Tests; D014376:Tuberculosis / Q000175:diagnosis
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D006017:Glycolipids; C045169:phenolic glycolipid I, Mycobacterium leprae