title: Induction of the SOS response in Escherichia coli by heavy ions.
abstract: The effectiveness of heavy ions in inducing the SOS response in E. coli cells has been measured by means of the SOS-chromotest. The SOS induction potency of ionizing radiation increases with increasing LET, to 40-60 keV/microns, reaches a maximum and then decreases at greater LET values. We conclude that the SOS-inducing damages in the case of ionizing radiation could be DNA injuries of a 'complex' type, e.g., DNA double-strand breaks or some kind of heavily damaged single-strand lesions.
authors.affiliation: Joint Institute for Nuclear Research, Dubna, U.S.S.R.
authors.forename: S
authors.initials: S
authors.lastname: Kozubek
authors.forename: E A
authors.initials: EA
authors.lastname: Krasavin
authors.forename: I
authors.initials: I
authors.lastname: Soska
authors.forename: V
authors.initials: V
authors.lastname: Drasil
authors.forename: K G
authors.initials: KG
authors.lastname: Amirtayev
authors.forename: B
authors.initials: B
authors.lastname: Tokarova
authors.forename: M
authors.initials: M
authors.lastname: Bonev
mesh_terms: D000469:Alkaline Phosphatase / Q000235:genetics / Q000378:metabolism; D002588:Cesium Radioisotopes; D003037:Cobalt Radioisotopes; D004260:DNA Repair / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics* / Q000528:radiation effects; D005720:Gamma Rays; D005798:Genes, Bacterial; D007700:Kinetics; D013014:SOS Response, Genetics / Q000528:radiation effects*; D001616:beta-Galactosidase / Q000235:genetics / Q000378:metabolism
chemical_list: D002588:Cesium Radioisotopes; D003037:Cobalt Radioisotopes; D000469:Alkaline Phosphatase; D001616:beta-Galactosidase