[A case of liver metastasis of gastric cancer which was made resectable by hypertheromo-chemo-radiotherapy].
A 60-year-old woman was diagnosed as having liver metastasis from gastric cancer 14 months after total gastrectomy and total pancreatectomy. The liver tumor was so huge and the complication, diabetes mellitus, was so severe that she was palliatively treated by hyperthermo-chemo-radiotherapy (HCR therapy) with 8-MHz capacitive heating system. Because hyperthermia for deep seated tumor is very difficult, irradiation (10 MV X-ray, 36 Gy) and systemic chemotherapy (CDDP, MMC) were combinedly used. After 10 session of hyperthermia, the tumor showed a remarkable regression in size, followed by S8 subsegmentectomy of the liver. Histologically, cancer cells were still viable in the midst of fibrosis around coagulation necrosis, while normal liver cells remained intact. Multidisciplinary HCR therapy is quite a useful modality for liver tumors and may serve to expand the indication for surgical operation.
Urade
M
M
Department of Surgery-II, School of Medicine, Kanazawa University, Japan.
Yonemura
Y
Y
Fujimura
T
T
Takegawa
S
S
Kamata
T
T
Fushida
Y
Y
Miyazaki
I
I
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D005260:Female; D006498:Hepatectomy; D006801:Humans; D006979:Hyperthermia, Induced; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery / Q000628:therapy; D008875:Middle Aged; D008937:Mitomycins / Q000008:administration & dosage; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D005641:Tegafur / Q000008:administration & dosage; D014498:Uracil / Q000008:administration & dosage
D008937:Mitomycins; D005641:Tegafur; D014498:Uracil; D002945:Cisplatin