Corneal subepithelial monoclonal kappa IgG deposits in essential cryoglobulinaemia.
A 60-year-old man suffering from photophobia and visual disturbances was found to have bilateral superficial corneal grey-white gelatinous deposits. An abnormal cold-precipitable serum component was found and characterised as homogeneous IgG-kappa immunoglobulin. Corneal immunohistochemical examination revealed subepithelial IgG-kappa deposits, focally replacing Bowman's layer. The patient underwent superficial keratectomy in both eyes with satisfactory visual results.
Kremer
I
I
Department of Ophthalmology, Beilinson Medical Center, Petah Tiqva, Israel.
Wright
P
P
Merin
S
S
Weiss
J
J
Pick
A I
AI
Kaufman
H
H
D003315:Cornea / Q000276:immunology*; D003449:Cryoglobulinemia / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007145:Immunoglobulin kappa-Chains / Q000032:analysis*; D008297:Male; D008875:Middle Aged
D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains