[Hemodynamic effects of a water soluble extract of Liriope spicata Lour on anesthetized cats].
The effects of water soluble extract of Liriope spicata on acute hemodynamics were studied in anesthetized cats. The results showed that LV dp/dt max was increased by 87%, whereas t-dp/dt max was shortened by 28% after administration of WSEL (1.75 g/kg, iv). At the same time CO, CI, SI, and SVWI were increased by 146, 151, 153, and 194%, respectively. HR was declined slightly. SVR was reduced by about 48%. WSEL (0.7 g/kg, iv) induced an increase of 38% in LV dp/dt max, 44% in CO, 50% in SI and a decrease of 20% in t-dp/dt max and 20% in SVR. Preliminary results indicated that WSEL increased ventricular contractile force and might increase cardiac pump function.
Gao
G Y
GY
Li
C X
CX
Duan
P
P
Han
X Y
XY
Yang
Y Q
YQ
D000818:Animals; D002415:Cats; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D006334:Heart Function Tests; D006439:Hemodynamics / Q000187:drug effects*; D008297:Male; D009200:Myocardial Contraction / Q000187:drug effects*; D013268:Stimulation, Chemical
D004365:Drugs, Chinese Herbal