[Immunogenic and immunomodulating properties of phospholipids from Coxiella burnetii].
It is proved that the challenging of the extract isolated from Coxiella (as a result of treatment with the mixture of chloroform and methanol) to animals doesn't provoke the appearance of antibodies to these microorganisms. It also doesn't cause the sensibilization of lymphocytes to Coxiella, but the extract can interact specifically with a serum containing antibodies to Coxiella. It permits to characterise the tested extract of Coxiella as a hapten with properties of adjuvant because it stimulates antibody-appearance.
Tokarevich
N K
NK
Daĭter
A B
AB
Lukacheva
M
M
Kartseva
N A
NA
D000276:Adjuvants, Immunologic / Q000502:physiology*; D000818:Animals; D000907:Antibodies, Bacterial / Q000276:immunology; D002642:Chick Embryo; D016997:Coxiella burnetii / Q000276:immunology*; D006168:Guinea Pigs; D008214:Lymphocytes / Q000276:immunology; D051379:Mice; D008809:Mice, Inbred C3H; D010743:Phospholipids / Q000276:immunology*; D011817:Rabbits
D000276:Adjuvants, Immunologic; D000907:Antibodies, Bacterial; D010743:Phospholipids
Izuchenie immunogennykh i immunomoduliruiushchikh svoĭstv fosfolipida koksiella berneta.