title: Bleeding patterns and acceptability among Norplant users in two Asian countries.
abstract: Changes in menstrual bleeding patterns are the most frequent reason for discontinuing NORPLANT during the first year of use. Although NORPLANT is used by more women in Asia than in any other region, the changes that occur among these women are not well documented. In pre-introductory clinical trials of NORPLANT in the Philippines and Sri Lanka, 175 women were enrolled with greater than 95% continuing the method after one year. Daily menstrual bleeding calendars were kept by 94% of subjects for nine months and by 66% for one year. In contrast to findings in previous studies which showed that approximately 60% of NORPLANT users had bleeding disruptions in the first year of use, almost all of these women experienced bleeding disruptions. In a one-year study of menstrual pattern changes, increased bleeding was found to occur with the same frequency as reduced bleeding. However, the changes experienced by the Asian women tended to be decreases, rather than increases, in menstrual bleeding.
authors.affiliation: Family Health International, Research Triangle Park, NC 27709.
authors.forename: S A
authors.initials: SA
authors.lastname: Balogh
authors.forename: S L
authors.initials: SL
authors.lastname: Klavon
authors.forename: S
authors.initials: S
authors.lastname: Basnayake
authors.forename: N
authors.initials: N
authors.lastname: Puertollano
authors.forename: R M
authors.initials: RM
authors.lastname: Ramos
authors.forename: G S
authors.initials: GS
authors.lastname: Grubb
mesh_terms: D000328:Adult; D003277:Contraceptives, Oral, Combined; D003710:Demography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016912:Levonorgestrel; D008598:Menstruation / Q000187:drug effects*; D009644:Norgestrel / Q000494:pharmacology; D010679:Philippines; D013188:Sri Lanka; D013237:Stereoisomerism
chemical_list: D003277:Contraceptives, Oral, Combined; D009644:Norgestrel; D016912:Levonorgestrel