title: Diabetic ketoacidosis in children.
abstract: Ketoacidosis is a metabolic alteration caused by absolute or relative insulin deficiency and oversecretion of glucagon. Prompt diagnosis and rapid initiation of treatment are mandatory to avoid the complications and fatal outcome. Reduction of plasma glucose to levels within acceptable limits, block of ketogenesis, re-establishment of hydroelectrolytic balance, correction of alterations of acido-base status are the most important goals in DKA treatment. However, all the corrections should be made slowly and under continuous control. Altered parameters must slope off very gradually to prevent dangerous hazards.
authors.affiliation: Clinica Pediatrica II, Università di Catania, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Reitano
mesh_terms: D001786:Blood Glucose / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D016883:Diabetic Ketoacidosis / Q000175:diagnosis / Q000209:etiology* / Q000378:metabolism / Q000628:therapy; D005934:Glucagon / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000172:deficiency / Q000378:metabolism; D007651:Keto Acids / Q000378:metabolism
chemical_list: D001786:Blood Glucose; D007328:Insulin; D007651:Keto Acids; D005934:Glucagon