Using the scoparone O-demethylase assay for categorizing types of hepatic microsomal monooxygenase inducers.
Kato
S
S
School of Pharmacy, Hokuriku University, Kanazawa, Japan.
Yamamoto
K
K
D000818:Animals; D003374:Coumarins / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D004790:Enzyme Induction; D008297:Male; D008748:Methylcholanthrene / Q000633:toxicity; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D006899:Mixed Function Oxygenases / Q000096:biosynthesis*; D010088:Oxidoreductases / Q000032:analysis*; D010090:Oxidoreductases, O-Demethylating / Q000032:analysis*; D010634:Phenobarbital / Q000633:toxicity; D011078:Polychlorinated Biphenyls / Q000633:toxicity; D051381:Rats; D011919:Rats, Inbred Strains
D003374:Coumarins; D008748:Methylcholanthrene; D011078:Polychlorinated Biphenyls; D006899:Mixed Function Oxygenases; D010088:Oxidoreductases; D010090:Oxidoreductases, O-Demethylating; C018145:scoparone; D010634:Phenobarbital