The serum protein content of human follicular fluid and its correlation with the maturity of oocytes.
The authors determined, by an immunochemical method, the alpha-1-antitrypsin, Gc globulin, prealbumin, albumin, haemopexin, transferrin, haptoglobin, IgA, IgG, ceruloplasmin, alpha-2-macroglobulin contents of 98 follicular fluids, 10 peritoneal fluids and 24 blood sera. Out of these proteins analysed, change in the concentration of alpha-1-antitrypsin showed correlation with the maturity and fertilisation of the oocyte. The alpha-1-antitrypsin content was 1.6 +/- 0.26 g/l in the case of mature oocytes, and 3.1 +/- 1.12 g/l in the case of immature ones. Fertilisation was also concomitant of low alpha-1-antitrypsin levels.
Nagy
B
B
First Department of Obstetrics and Gynecology, Semmelweis Medical University, Budapest, Hungary.
Pulay
T
T
Szarka
G
G
Csömör
S
S
D000328:Adult; D000367:Age Factors; D001798:Blood Proteins / Q000032:analysis*; D005260:Female; D006801:Humans; D007120:Immunochemistry; D005779:Immunodiffusion; D009865:Oocytes / Q000502:physiology*; D006080:Ovarian Follicle / Q000032:analysis*; D010533:Peritoneal Lavage; D000515:alpha 1-Antitrypsin / Q000032:analysis
D001798:Blood Proteins; D000515:alpha 1-Antitrypsin