Treatment of hepatic cancer by hepatic arterial infusion chemotherapy.
A group of 213 patients with advanced primary hepatic carcinomas and 353 patients with metastatic liver cancers were treated by the prolonged intra-arterial infusion of mitomycin C and 5-fluorouracil through a surgically placed catheter over a period of time from 1966 to 1987. Regionalized chemotherapy by hepatic arterial infusion for hepatic cancer produced a greater degree and higher incidence of response than are obtainable through systemic administration. Intra-arterial infusion chemotherapy seems to offer an exciting new avenue of approach to the control of hepatic cancer.
Miura
T
T
Department of Surgery, Hanzomon Hospital, Tokyo, Japan.
D004621:Embolization, Therapeutic; D005472:Fluorouracil / Q000008:administration & dosage*; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy*; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage*
D008937:Mitomycins; D016685:Mitomycin; D005472:Fluorouracil