title: Elevated soluble CD8 levels in sera of human immunodeficiency virus-infected populations.
abstract: Soluble CD8 levels in sera were quantitated in asymptomatic intravenous drug abusers, homosexuals, and patients with lymphadenopathy or acquired immunodeficiency syndrome. Soluble CD8 levels were elevated in human immunodeficiency virus-seronegative intravenous drug abusers and homosexuals, probably reflecting infections like cytomegalovirus. The sera of human immunodeficiency virus-seropositive groups of patients with human immunodeficiency virus infection also had elevated levels of soluble CD8, reflecting infections like cytomegalovirus and human immunodeficiency virus infection.
authors.affiliation: R. A. Cooke Institute of Allergy, St. Luke's-Roosevelt Hospital Center, New York, New York 10019.
authors.forename: M M
authors.initials: MM
authors.lastname: Reddy
authors.forename: M
authors.initials: M
authors.lastname: Lange
authors.forename: M H
authors.initials: MH
authors.lastname: Grieco
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology*; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis*; D016827:CD8 Antigens; D006679:HIV Seropositivity / Q000276:immunology; D006716:Homosexuality; D006801:Humans; D019966:Substance-Related Disorders / Q000150:complications; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D000945:Antigens, Differentiation, T-Lymphocyte; D016827:CD8 Antigens