title: Group A streptococcal pyrogenic exotoxin (scarlet fever toxin) type A and blastogen A are the same protein.
abstract: Group A streptococcal pyrogenic exotoxins A, B, and C (also known as scarlet fever toxins and erythrogenic toxins) were evaluated for relatedness to another streptococcus-derived lymphocyte mitogen, blastogen A. Streptococcal pyrogenic exotoxin A and blastogen A were immunologically cross-reactive and shared the same molecular weight, N-terminal amino acid sequence, and capacity to stimulate rabbit splenocyte proliferation nonspecifically.
authors.affiliation: Department of Microbiology, University of Minnesota, Minneapolis 55455.
authors.forename: P M
authors.initials: PM
authors.lastname: Schlievert
authors.forename: E D
authors.initials: ED
authors.lastname: Gray
mesh_terms: D001426:Bacterial Proteins / Q000032:analysis*; D004591:Electrophoresis, Polyacrylamide Gel; D005098:Exotoxins / Q000032:analysis*; D015151:Immunoblotting; D005779:Immunodiffusion; D008565:Membrane Proteins; D008934:Mitogens / Q000032:analysis*; D011749:Pyrogens / Q000032:analysis*; D013290:Streptococcal Infections / Q000276:immunology; D013297:Streptococcus pyogenes / Q000276:immunology*
chemical_list: D001426:Bacterial Proteins; D005098:Exotoxins; D008565:Membrane Proteins; D008934:Mitogens; D011749:Pyrogens; C117980:SpeA protein, Streptococcus pyogenes; C027951:erythrogenic toxin; C034866:streptococcal group A mitogen