[Humoral mechanisms of the membrano-toxic effects of mastocytoma P815 and leukemia EL4 cells].
The membranotoxicity activity of P815 and EL4 tumor cells and their humoral factors containing in cultural supernatants and ascitic fluids was estimated. Tumor cells and their humoral factors exert dose-dependent membranotoxicity effect on murine splenocytes and lymphoblasts. Normal murine splenocytes and renal cells have no membranotoxicity properties. Thus tumor cells membranotoxicity effect is carried out by humoral mechanism.
Medvedev
A E
AE
Fuks
B B
BB
D000818:Animals; D001202:Ascitic Fluid / Q000276:immunology; D003470:Culture Media; D003601:Cytotoxicity Tests, Immunologic; D007942:Leukemia, Experimental / Q000276:immunology / Q000473:pathology*; D008214:Lymphocytes / Q000276:immunology; D012515:Mast-Cell Sarcoma / Q000276:immunology / Q000473:pathology*; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D012513:Sarcoma, Experimental / Q000276:immunology / Q000473:pathology*; D013154:Spleen / Q000276:immunology; D014407:Tumor Cells, Cultured
D003470:Culture Media
Isledovanie gumoral'nogo mekhanizma membranotoksicheskogo éffekta kletok mastotsitomy P815 i leĭkoza EL4.