title: The etiology of genital ulceration in Rwanda.
abstract: The etiology of genital ulcer disease was determined in 210 consecutive patients (110 men and 100 women) who presented at a clinic in Kigali, Rwanda, because of genital ulcers. When mixed infections are included, syphilis (21%), chancroid (24%), and genital herpes (17%) were about equally frequent in men. Lymphogranuloma venereum with ulceration was found in 11% of patients. Syphilis (40%) was the most common diagnosis in women; genital herpes (20%), lymphogranuloma venereum with ulceration (19%) and chancroid (12%) also were frequent diagnoses. Microscopic examination for treponemes after silver-impregnation staining had a poor sensitivity and specificity for the diagnosis of primary syphilis. Overall, 59% of the patients (43% of the men and 77% of the women) had IgG antibodies to the human immunodeficiency virus.
authors.affiliation: Centre Hospitalier de Kigali, Rwanda.
authors.forename: J
authors.initials: J
authors.lastname: Bogaerts
authors.forename: C A
authors.initials: CA
authors.lastname: Ricart
authors.forename: E
authors.initials: E
authors.lastname: Van Dyck
authors.forename: P
authors.initials: P
authors.lastname: Piot
mesh_terms: D000293:Adolescent; D000328:Adult; D002602:Chancroid / Q000175:diagnosis; D002690:Chlamydia Infections / Q000175:diagnosis; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D005189:False Positive Reactions; D005260:Female; D005831:Genital Diseases, Female / Q000175:diagnosis / Q000209:etiology*; D005832:Genital Diseases, Male / Q000175:diagnosis / Q000209:etiology*; D006069:Gonorrhea / Q000175:diagnosis; D015483:HIV Antibodies / Q000032:analysis; D015658:HIV Infections / Q000175:diagnosis; D006191:Haemophilus ducreyi / Q000302:isolation & purification; D006558:Herpes Genitalis / Q000175:diagnosis; D006801:Humans; D008219:Lymphogranuloma Venereum / Q000175:diagnosis; D008297:Male; D009344:Neisseria gonorrhoeae / Q000302:isolation & purification; D011237:Predictive Value of Tests; D012432:Rwanda; D013587:Syphilis / Q000175:diagnosis; D013588:Syphilis Serodiagnosis; D014456:Ulcer / Q000175:diagnosis / Q000209:etiology*
chemical_list: D015483:HIV Antibodies