[L-tyrosine: a long term treatment of Parkinson's disease].
That l-dopa represents a major advance in Parkinson treatment should not hide that a number of problems remain unanswered: on-off effects, transient improvements... Based on the beneficial effects of l-tyrosine in dopamine dependent depressions and narcolepsy, five naive patients diagnosed after sleep polygraphy criteria and five l-dopa and/or dopamine agonist treated patients were prescribed l-tyrosine as a long-term treatment. For some patients, 3 years of L-tyrosine treatment was followed by better clinical results and many fewer side effects than with L-DOPA or dopamine agonists. However, the theoretical long-term sparing neurons potentiality of approach requires further studies.
Lemoine
P
P
Unité clinique de Psychiatrie biologique, C.H.S. Le Vinatier, Lyon-Bron.
Robelin
N
N
Sebert
P
P
Mouret
J
J
D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy*; D014443:Tyrosine / Q000627:therapeutic use*
D014443:Tyrosine
La L-tyrosine: traitement au long cours de la maladie de Parkinson.