A defect in mitochondrial electron-transport activity (NADH-coenzyme Q oxidoreductase) in Leber's hereditary optic neuropathy.
Parker
W D
WD
Department of Neurology, University of Colorado School of Medicine, Denver.
Oley
C A
CA
Parks
J K
JK
D004579:Electron Transport; D015417:Hereditary Sensory and Motor Neuropathy / Q000201:enzymology*; D006801:Humans; D008297:Male; D008928:Mitochondria / Q000201:enzymology* / Q000378:metabolism; D016660:NAD(P)H Dehydrogenase (Quinone); D015418:Optic Atrophies, Hereditary / Q000201:enzymology* / Q000235:genetics; D011808:Quinone Reductases / Q000172:deficiency* / Q000235:genetics; D012402:Rotenone / Q000378:metabolism
D012402:Rotenone; D016660:NAD(P)H Dehydrogenase (Quinone); D011808:Quinone Reductases