Comparison of giant cell granuloma of the jaw and non-ossifying fibroma.
The present investigation concerns 113 patients with peripheral giant cell granulomas, 52 patients with central giant cell granulomas and 18 patients with non-ossifying fibromas of the long bones. The purpose was to analyze the possible equivalence of central giant cell granulomas with non-ossifying fibromas. Non-ossifying fibromas occur at a lower mean age than central giant cell granulomas and moreover, although central giant cell granulomas may exhibit areas that are histologically similar to non-ossifying fibromas, the presence of other features, especially bone formation, warrants a recognition of central giant cell granulomas and non-ossifying fibromas as separate entities.
Slootweg
P J
PJ
Pathology Institute, Utrecht, The Netherlands.
D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000473:pathology*; D002675:Child, Preschool; D005260:Female; D005347:Fibroblasts / Q000473:pathology; D005350:Fibroma / Q000473:pathology*; D006101:Granuloma, Giant Cell / Q000473:pathology*; D006470:Hemorrhage / Q000473:pathology; D006801:Humans; D007571:Jaw Diseases / Q000473:pathology*; D008297:Male; D008938:Mitosis; D009999:Ossification, Heterotopic; D010006:Osteoblasts / Q000473:pathology