title: Treatment of hidradenitis suppurativa with combination hypothalamic-pituitary-ovarian and adrenal suppression. A case report.
abstract: A 33-year-old woman with severe familial hidradenitis suppurativa of the vulva and perineum was treated with a combination of dexamethasone and a new synthetic gonadotropin releasing hormone agonist, leuprolide acetate. The clinical improvement paralleled the adrenal and ovarian suppression, as demonstrated by falling blood levels of testosterone, dehydroepiandrosterone sulfate, androstenedione and estradiol.
authors.affiliation: Department of Dermatology, Cleveland Clinic Foundation, OH 44106.
authors.forename: C
authors.initials: C
authors.lastname: Camisa
authors.forename: C
authors.initials: C
authors.lastname: Sexton
authors.forename: C
authors.initials: C
authors.lastname: Friedman
mesh_terms: D000328:Adult; D001050:Apocrine Glands; D003864:Depression, Chemical; D003907:Dexamethasone / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage / Q000627:therapeutic use; D006728:Hormones / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007031:Hypothalamus / Q000187:drug effects*; D007249:Inflammation; D016729:Leuprolide; D008297:Male; D010053:Ovary / Q000187:drug effects*; D010902:Pituitary Gland / Q000187:drug effects*; D013492:Suppuration; D013543:Sweat Gland Diseases / Q000188:drug therapy*; D013545:Sweat Glands
chemical_list: D006728:Hormones; D007987:Gonadotropin-Releasing Hormone; D003907:Dexamethasone; D016729:Leuprolide