Center variability.
1. Variation among centers accounted for about one-third of the assignable variation in kidney transplant graft survival. 2. Centers varied systematically in their use of CsA and of pretransplant transfusions and in transplant cold ischemia times--factors strongly related to graft outcome. About 90% of patients received CsA. 3. At some centers, graft survival rates in the low 90% range were attained for first transplants from cadaver donors. 4. Variation among centers was less noticeable at high survival rates. Nearly all centers had good results using HLA-identical sibling donors. 5. Centers with better survival rates tended to treat fewer transplants with CsA. There was a modest, but potentially interesting, negative correlation.
Mickey
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D000704:Analysis of Variance; D003524:Cyclosporins / Q000627:therapeutic use; D005260:Female; D006085:Graft Survival; D006680:HLA Antigens; D006268:Health Facilities; D006801:Humans; D016030:Kidney Transplantation / Q000276:immunology / Q000706:statistics & numerical data*; D008297:Male; D012042:Registries
D003524:Cyclosporins; D006680:HLA Antigens