[Energy metabolism characteristics of various sections of the rat brain under the action of ethanol and lithium carbonate].
Acute alcohol intoxication (AAI, 2.5 g/kg intraperitoneally) was found to be followed by ATP level increase in all brain regions under study. As a result, creatinine kinase and ATPase activities were decreased. Following administration of lithium carbonate (80 mg/kg intragastrically) and ethanol, the content of ATP was increased in the thalamus and cerebellum regions while ATPase activity and non-organic phosphorus level were decreased. Under this condition creatinine kinase activity in the brain cortex as well as in the cerebellum increased as compared to AAI group of animals.
Korablev
M V
MV
Lelevich
V V
VV
D000427:Alcohol Deterrents / Q000494:pharmacology*; D000435:Alcoholic Intoxication / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D004347:Drug Interactions; D004734:Energy Metabolism / Q000187:drug effects* / Q000502:physiology; D000431:Ethanol / Q000494:pharmacology*; D008094:Lithium / Q000494:pharmacology*; D016651:Lithium Carbonate; D008297:Male; D051381:Rats
D000427:Alcohol Deterrents; D016651:Lithium Carbonate; D000431:Ethanol; D008094:Lithium
Kharakteristika énergeticheskogo obmena v raznykh otdelakh golovnogo mozga krys pri deĭstvii étanola i karbonata litiia.