title: Corneal ulcers associated with disposable hydrogel contact lenses.
abstract: Four patients developed corneal ulcers associated with the use of disposable extended-wear hydrogel contact lenses. Bacteria were recovered from corneal ulcers in three of the patients. Three patients discarded their contact lenses after ten or more days of extended wear; the corneal ulcers in these patients developed toward the end of the wearing cycle. The fourth patient removed her contact lenses every two days for cleaning and disinfection and discarded them for a new pair on a weekly basis. Improper lens hygiene was noted in only one patient. All corneal ulcers responded to antibiotic treatment. In three patients visual acuity returned to normal, but scarring of one patient's cornea resulted in a visual acuity of 20/60.
authors.affiliation: Department of Ophthalmology, UCLA School of Medicine.
authors.forename: J P
authors.initials: JP
authors.lastname: Dunn
authors.forename: B J
authors.initials: BJ
authors.lastname: Mondino
authors.forename: B A
authors.initials: BA
authors.lastname: Weissman
authors.forename: P B
authors.initials: PB
authors.lastname: Donzis
authors.forename: D O
authors.initials: DO
authors.lastname: Kikkawa
mesh_terms: D000328:Adult; D001424:Bacterial Infections; D003262:Contact Lenses, Extended-Wear / Q000009:adverse effects*; D003320:Corneal Ulcer / Q000209:etiology*; D004209:Disposable Equipment / Q000009:adverse effects*; D005260:Female; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D011092:Polyethylene Glycols; D011425:Propionibacterium acnes; D011552:Pseudomonas Infections; D011550:Pseudomonas aeruginosa; D013290:Streptococcal Infections
chemical_list: D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D011092:Polyethylene Glycols