[A case of breast cancer with multiple bone metastases effectively treated with UFT and tamoxifen].
A 51-year-old female with advanced breast cancer involving multiple bone metastases was daily administered 400 mg of UFT and 20 mg of tamoxifen. X-ray examination revealed remarkable osteosclerosis. Laboratory data revealed a high serum alkali phosphatase level of 820 mU/ml(at 3 months), which gradually decreased to 274 mU/ml with pain relief at 11 months after the beginning of this chemotherapy.
Endo
F
F
Dept. of Orthopaedic Surgery, School of Medicine, Chiba University.
Ishii
T
T
Kito
T
T
D000469:Alkaline Phosphatase / Q000097:blood; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000556:secondary; D001943:Breast Neoplasms / Q000473:pathology*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008875:Middle Aged; D011859:Radiography; D012074:Remission Induction; D013629:Tamoxifen / Q000008:administration & dosage* / Q000627:therapeutic use; D005641:Tegafur / Q000008:administration & dosage; D014498:Uracil / Q000008:administration & dosage
D013629:Tamoxifen; D005641:Tegafur; D014498:Uracil; D000469:Alkaline Phosphatase