Ovulation induction and pregnancy with an estrogen-gonadotropin stimulation technique in a menopausal woman with marked hypoplastic ovaries.
A case is described of a woman with ovarian failure and documented atrophic ovaries in whom ovulation was achieved with the use of high-dose estrogen and human menopausal gonadotropins. The proposed mechanism involves a reduction in the elevated gonadotropins, which restored an adequate number of receptors. Thus sensitivity to exogenous menotropins was reestablished.
Check
J H
JH
Department of Obstetrics and Gynecology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA.
Chase
J S
JS
Wu
C H
CH
Adelson
H G
HG
D000328:Adult; D004997:Ethinyl Estradiol / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008593:Menopause / Q000502:physiology*; D008594:Menopause, Premature / Q000502:physiology*; D008596:Menotropins / Q000008:administration & dosage; D010053:Ovary / Q000473:pathology* / Q000503:physiopathology; D010062:Ovulation Induction / Q000379:methods; D011247:Pregnancy
D004997:Ethinyl Estradiol; D008596:Menotropins