[Studies on the antiarrhythmic effects of leaves of Dendropanax chevalieri (Vig.) Merr. et Chun].
Aqueous extract of the leaves of Dendropanax chevalieri (DC), administrated orally, showed prominent protective effect against arrhythmias induced by iv aconitine CaCl2 (120mg/kg) in mice and BaCl2 (4mg/kg) in rats. In anesthetized rabbits, the duration of arrhythmia elicited by ivAdr 75 micrograms/kg was markedly shortened by iv DC 0.4g/kg. It might also obviously delay the onset of arrhythmias and cardiac electricity disappearance evoked by ouabain perfusing consistently into isolated guinea-pig hearts.
Huang
J Y
JY
Liu
C M
CM
Qi
P L
PL
Liu
K M
KM
D000818:Animals; D001145:Arrhythmias, Cardiac / Q000188:drug therapy*; D001794:Blood Pressure / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D006168:Guinea Pigs; D006339:Heart Rate / Q000187:drug effects; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D011817:Rabbits; D051381:Rats; D011919:Rats, Inbred Strains
D004365:Drugs, Chinese Herbal