title: Avian thymic hormone (ATH) is a parvalbumin.
abstract: Amino acid sequence analysis of a protein from chicken thymus tissue which promotes immunological maturity in chicken bone marrow cells in culture has established sequences of a 45-residue fragment, a 24-residue fragment and a 9-residue and an 8-residue peptide. Independent comparison of the 45- and 24-residue fragments with known amino acid sequences by computer search has unequivocally identified avian thymic hormone as a parvalbumin. This is the first demonstration that a protein previously identified by a biological function is a parvalbumin.
authors.affiliation: Department of Biochemistry, University of Georgia, Athens 30602.
authors.forename: J M
authors.initials: JM
authors.lastname: Brewer
authors.forename: J K
authors.initials: JK
authors.lastname: Wunderlich
authors.forename: D H
authors.initials: DH
authors.lastname: Kim
authors.forename: M Y
authors.initials: MY
authors.lastname: Carr
authors.forename: G G
authors.initials: GG
authors.lastname: Beach
authors.forename: W L
authors.initials: WL
authors.lastname: Ragland
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002645:Chickens / Q000378:metabolism*; D002918:Chymotrypsin; D007256:Information Systems; D008969:Molecular Sequence Data; D009124:Muscle Proteins; D010320:Parvalbumins; D010434:Pepsin A; D010446:Peptide Fragments; D012689:Sequence Homology, Nucleic Acid; D013950:Thymus Gland / Q000032:analysis; D013951:Thymus Hormones; D014357:Trypsin
chemical_list: D009124:Muscle Proteins; D010320:Parvalbumins; D010446:Peptide Fragments; D013951:Thymus Hormones; D002918:Chymotrypsin; D014357:Trypsin; D010434:Pepsin A