title: Long-term follow-up of patients with residual thyroid autonomy after surgical treatment of Plummer's disease.
abstract: Residual autonomously functioning tissue after surgical treatment of Plummer's disease was previously shown to be present in 18 of 87 patients; no clear symptoms were found in these cases. In the present study the results are presented of a second follow-up study in 15 of these 18 patients, an average of 12.2 years after the operation (or 5.8 years after the previous study). Overt hyperthyroidism was found in one case, minor (scintigraphic and/or biochemical) signs of progression in nine others. It is concluded that clinical recurrence may eventually develop in some operated patients, but rarely within ten years.
authors.affiliation: VU Ziekenhuis, Department of Medicine, Amsterdam, The Netherlands.
authors.forename: J D
authors.initials: JD
authors.lastname: Wiener
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013577:Syndrome; D013961:Thyroid Gland / Q000000981:diagnostic imaging / Q000503:physiopathology*; D013963:Thyroid Hormones / Q000097:blood
chemical_list: D013963:Thyroid Hormones