title: [The effect of chemical sympathectomy on the cell kinetics of gastric mucosa in golden hamsters].
abstract: The effects of chemical sympathectomy on the differentiation of the generative cells, superficial epithelial cells and gastrin cells of the gastric mucosa of hamster were examined by 3H-thymidine autoradiography. The labeling indices of the generative cell zone in the gastric mucosa and antral gastrin cells showed a transient significant decrease after chemical sympathectomy, and then they were gradually restore with time. After 4 weeks onward, the labeling indices of the generative cells showed a slightly low value compared with those in controls. The renewal of superficial epithelial cells and gastrin cells was examined in the hamster sympathectomized for 4 weeks. The time required for the differentiation to PAS positive superficial epithelial cells or gastrin cells had a tendency to elogate after chemical sympathectomy. These results suggest that chemical sympathectomy played an inhibitive action on the proliferation and the differentiation of gastric mucosa.
authors.forename: C
authors.initials: C
authors.lastname: Nakajima
authors.forename: T
authors.initials: T
authors.lastname: Azuma
authors.forename: Y
authors.initials: Y
authors.lastname: Magami
authors.forename: Z
authors.initials: Z
authors.lastname: Sasaki
authors.forename: K
authors.initials: K
authors.lastname: Kawai
authors.forename: H
authors.initials: H
authors.lastname: Inokuchi
authors.forename: T
authors.initials: T
authors.lastname: Kawai
authors.forename: T
authors.initials: T
authors.lastname: Seki
authors.forename: Y
authors.initials: Y
authors.lastname: Harada
authors.forename: T
authors.initials: T
authors.lastname: Saito
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D002455:Cell Division; D006224:Cricetinae; D005753:Gastric Mucosa / Q000166:cytology*; D006892:Hydroxydopamines; D008297:Male; D008647:Mesocricetus; D016627:Oxidopamine; D013563:Sympathectomy, Chemical
chemical_list: D006892:Hydroxydopamines; D016627:Oxidopamine