title: Glycaemic responses to three different honeys given to normal and alloxan-diabetic rabbits.
abstract: Blood glucose levels of normal and diabetic rabbits were determined after oral administration of graded doses of three different types of honeys; namely honeys of Apis florea (Small-Bee) and Apis dorsata (Large-Bee) and an adulterated commercial honey. The chemical analysis showed that commercial honey was adulterated with a saturated sucrose solution as it contained lower ash but higher nonreducing sugar levels than the natural ones. Oral administration of pure small or large-bee honeys in 5 ml/kg/doses could not produce a significant (P greater than 0.05) increase in glucose levels in normal and alloxan-diabetic rabbits whereas the adulterated honey significantly raised the blood glucose levels in normal and hyperglycaemic rabbits even at this low dosage. In higher doses of 10 ml/kg and 15 ml/kg body weight, all the three honeys produced a significant (P less than 0.05 or P less than 0.001) rise in blood glucose levels of normal as well as alloxan-diabetic rabbits. It may, therefore, be suggested that pure natural honeys in low doses may be recommended as a source of carbohydrates and even as a sweetening agent in place of sucrose to the human patients suffering from diabetes mellitus (JPMA 39: 107, 1989).
authors.forename: M S
authors.initials: MS
authors.lastname: Akhtar
authors.forename: M S
authors.initials: MS
authors.lastname: Khan
mesh_terms: D000284:Administration, Oral; D000496:Alloxan; D000818:Animals; D001786:Blood Glucose / Q000032:analysis*; D002241:Carbohydrates / Q000008:administration & dosage / Q000032:analysis; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000378:metabolism*; D004032:Diet; D006722:Honey / Q000032:analysis; D011817:Rabbits
chemical_list: D001786:Blood Glucose; D002241:Carbohydrates; D000496:Alloxan