title: Lubrication of selected salivary molecules and artificial salivas.
abstract: The lubrication regime displayed by human salivas (parotid and submandibular-sublingual), purified salivary molecules (the mucins MG1 and MG2 and alpha-amylases), and selected artificial salivas (Oracare D, Saliva Substitute, and Orthana) was assessed in vitro using a friction-testing device. Thin-film (boundary) lubrication was observed for all of the salivary samples and two of the artificial salivas examined. Oracare D, a glycerol-based artificial saliva, was the exception since it lubricated by a thick-film (hydrodynamic) regime. On a molar basis, the best lubricants of the purified salivary molecules were MG1 greater than MG2 approximately nonglycosylated alpha-amylases approximately glycosylated alpha-amylases.
authors.forename: A
authors.initials: A
authors.lastname: Aguirre
authors.forename: B
authors.initials: B
authors.lastname: Mendoza
authors.forename: M S
authors.initials: MS
authors.lastname: Reddy
authors.forename: F A
authors.initials: FA
authors.lastname: Scannapieco
authors.forename: M J
authors.initials: MJ
authors.lastname: Levine
authors.forename: M N
authors.initials: MN
authors.lastname: Hatton
mesh_terms: D000681:Amylases / Q000502:physiology*; D006801:Humans; D009067:Mouthwashes; D009077:Mucins / Q000502:physiology*; D012463:Saliva / Q000502:physiology*; D012464:Saliva, Artificial; D014783:Viscosity
chemical_list: D009067:Mouthwashes; D009077:Mucins; D012464:Saliva, Artificial; D000681:Amylases