Rhesus sensitization after midtrimester genetic amniocentesis.
In 944 Rh-negative patients who received rhesus immunoglobulin (anti-D) following genetic amniocentesis, not a single case of Rh sensitization occurred. Routine administration of a small dose (100 micrograms) of anti-D is effective in preventing Rh sensitization after midtrimester amniocentesis.
Brandenburg
H
H
Department of Clinical Genetics, Academic Hospital Dijkzigt, Erasmus University, Rotterdam, The Netherlands.
Jahoda
M G
MG
Pijpers
L
L
Wladimiroff
J W
JW
D000649:Amniocentesis; D005260:Female; D006801:Humans; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D012203:Rh Isoimmunization / Q000209:etiology* / Q000235:genetics; D012204:Rh-Hr Blood-Group System / Q000235:genetics; D012307:Risk Factors
D012204:Rh-Hr Blood-Group System