title: Are SCE frequencies indicative of adaptive response of plant cells?
abstract: Low-dose pretreatments with maleic hydrazide, mitomycin C, and N-methyl-N-nitrosourea or sublethal heat shock were tested with regard to their effect on sister-chromatid exchange (SCE) induction by high doses of the same mutagens administered 2 h later to root-tip meristems of Vicia faba. Consecutive treatments resulted in either additive or, in a minority of experiments, in below-additive SCE frequencies. A model is proposed to explain the conflicting data reported on adaptation to SCE and aberration induction.
authors.affiliation: Zentralinstitut für Genetik und Kulturpflanzenforschung, Gatersleben G.D.R.
authors.forename: I
authors.initials: I
authors.lastname: Schubert
authors.forename: K
authors.initials: K
authors.lastname: Heindorff
mesh_terms: D000064:Acclimatization; D006358:Hot Temperature; D008300:Maleic Hydrazide / Q000494:pharmacology*; D008770:Methylnitrosourea / Q000494:pharmacology*; D016685:Mitomycin; D008937:Mitomycins / Q000494:pharmacology*; D009153:Mutagens; D009154:Mutation; D018521:Plant Physiological Phenomena; D010944:Plants / Q000187:drug effects / Q000235:genetics*; D011724:Pyridazines / Q000494:pharmacology*; D012854:Sister Chromatid Exchange
chemical_list: D008937:Mitomycins; D009153:Mutagens; D011724:Pyridazines; D016685:Mitomycin; D008770:Methylnitrosourea; D008300:Maleic Hydrazide