title: The clinical usefulness of serum fructosamine and HbAlc in patients with NIDDM.
abstract: To evaluate the clinical values of serum fructosamine and HbAlc, serum fructosamine and HbAlc were assessed in 50 normal controls and 36 patients with NIDDM (non-insulin-dependent diabetes mellitus). And we studied 10 patients selected at random among the 36 patients with NIDDM. The values of serum fructosamine and HbAlc in controls were 2.1 mmol/L and 5.3%, respectively. The levels of serum fructosamine and HbAlc were significantly higher in NIDDM patients (3.27 mmol/L and 8.8%, respectively, p less than 0.005) compared with those in the controls. The serum fructosamine was significantly correlated with fasting plasma glucose and HbAlc (r = 0.78, p less than 0.78, p less than 0.001; r = 0.76, p less than 0.005, respectively). Also, in retrograde study, serum fructosamine concentration had a significant correlation to fasting plasma glucose determined 2 weeks before (r = 0.72, p less than 0.002), and 4 weeks before (r = 0.54, p less than 0.005). It is concluded that serum fructosamine measurement may be useful in monitoring short-term control of plasma glucose in patients with NIDDM.
authors.forename: S Y
authors.initials: SY
authors.lastname: Lim
authors.forename: Y M
authors.initials: YM
authors.lastname: Jhoo
authors.forename: S S
authors.initials: SS
authors.lastname: Lee
authors.forename: M H
authors.initials: MH
authors.lastname: Lee
authors.forename: E S
authors.initials: ES
authors.lastname: Chung
authors.forename: S J
authors.initials: SJ
authors.lastname: Lee
mesh_terms: D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D004784:Environmental Monitoring; D005260:Female; D019270:Fructosamine; D006442:Glycated Hemoglobin / Q000032:analysis*; D006595:Hexosamines / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D001786:Blood Glucose; D019270:Fructosamine; D006442:Glycated Hemoglobin; D006595:Hexosamines