title: Changes of immunological parameters in immunocompromised patients under selective decontamination of the digestive tract. Third Part: Behaviour of some plasma proteins.
abstract: We studied the importance of changes in plasma protein concentrations in patients with hematologic systemic diseases treated by selective decontamination of the digestive tract. The concentrations of albumin, acute-phase proteins, immunoglobulins and fibronectin were determined by laser nephelometry in 125 serum samples of eight patients. Results obtained allow the following conclusions: 1. There was a correlation between the clinical condition and concentrations of acid alpha-1-glycoprotein, IgG, CRP and fibronectin. These concentrations might be important for assessment of the course of the disease, effectiveness of therapy and the detection of pathogenetic relations. 2. The acid alpha-1-glycoprotein is of particular importance since relations exist between changes in its concentration and therapeutic results as well as the prognosis of the disease.
authors.affiliation: Institute of Immunology, Military Medical Academy, Bad Saarow, GDR.
authors.forename: E
authors.initials: E
authors.lastname: Wulf
authors.forename: H
authors.initials: H
authors.lastname: Koch
authors.forename: R
authors.initials: R
authors.lastname: Gille
mesh_terms: D000209:Acute-Phase Proteins / Q000378:metabolism; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001798:Blood Proteins / Q000378:metabolism; D004064:Digestive System / Q000187:drug effects / Q000382:microbiology; D006402:Hematologic Diseases / Q000097:blood / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D007108:Immune Tolerance / Q000187:drug effects* / Q000276:immunology; D017053:Infection Control
chemical_list: D000209:Acute-Phase Proteins; D000890:Anti-Infective Agents; D001798:Blood Proteins