Effects of octopaminergic substances on the labellar lobe spreading response in the blowfly Protophormia terraenovae.
The effectiveness of labellar taste input in evoking the feeding response of labellar lobe spreading in Protophormia was greatly increased by injecting flies with clonidine or DL-octopamine. This effect was suppressed when either drug was administered together with yohimbine; when injected alone, the latter determined a strong decrease in the feeding responses. Drug treatment did not determine variations in labellar taste input or evoke spontaneous activity in the denervated muscle. These results suggest that the injected substances lower the feeding-related reflex threshold at the CNS level.
Angioy
A M
AM
Dipartimento di Biologia Sperimentale, Università di Cagliari, Italy.
Barbarossa
I T
IT
Crnjar
R
R
Liscia
A
A
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D002490:Central Nervous System / Q000187:drug effects / Q000502:physiology; D003000:Clonidine / Q000494:pharmacology*; D004175:Diptera / Q000187:drug effects / Q000502:physiology*; D004435:Eating / Q000187:drug effects; D004594:Electrophysiology; D009132:Muscles / Q000502:physiology; D009655:Octopamine / Q000494:pharmacology*; D011941:Receptors, Adrenergic / Q000502:physiology; D017982:Receptors, Biogenic Amine; D013650:Taste Buds / Q000187:drug effects / Q000502:physiology; D015016:Yohimbine / Q000494:pharmacology
D011941:Receptors, Adrenergic; D017982:Receptors, Biogenic Amine; C027604:norsynephrine receptor; D009655:Octopamine; D015016:Yohimbine; D003000:Clonidine