[Long-term results following surgery or radioiodine treatment of solitary autonomous adenoma of the thyroid gland].
128 patients were investigated after surgery (n = 72) or 131-iodine therapy (n = 56) of a scintigraphically solitary, hyperfunctioning adenoma of the thyroid gland. The median follow-up period amounted to 10.6 years. Recurrent hyperthyroidism was observed in six patients after surgery and in one patient after 131-iodine therapy. Hypothyroidism occurred in one patient after 131-iodine therapy. The percentage of 131-iodine treated patients with a normal TSH-response to TSH-releasing hormone (TRH) increased during the follow-up period from 57 to 90%, whereas after surgery the percentage of patients showing a normal TSH-response to TSH decreased from 58 to 31%. This latter observation points to persistent hyperfunctioning tissue areas inducing late recurrent hyperthyroidism in 8.3% of the patients who underwent surgery.
Müller-Gärtner
H W
HW
Abteilung für Nuklearmedizin, Universitätskrankenhaus Hamburg-Eppendorf.
Schneider
C
C
Riechert
B
B
Kayser
D
D
Kremer
B
B
D000236:Adenoma / Q000532:radiotherapy / Q000601:surgery*; D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006980:Hyperthyroidism / Q000532:radiotherapy / Q000601:surgery*; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000097:blood; D011183:Postoperative Complications / Q000097:blood; D013964:Thyroid Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D013965:Thyroidectomy; D013972:Thyrotropin / Q000097:blood; D013973:Thyrotropin-Releasing Hormone
D007457:Iodine Radioisotopes; D013973:Thyrotropin-Releasing Hormone; D013972:Thyrotropin
Langzeitergebnisse nach Operation oder Radiojodbehandlung des solitären autonomen Adenoms der Schilddrüse.