title: Ultrastructure of multinucleated giant myeloma cells: report of one case.
abstract: The ultrastructure of multinucleated giant myeloma cells obtained from an IgA kappa myeloma patient was investigated. The characteristic findings were marked nucleocytoplasmic asynchrony, irregular nuclear indentation, branched mitochondria, and Golgi apparatus surrounded by nuclei. The patient died of renal failure only 6 months after diagnosis.
authors.affiliation: Third Department of Medicine, Gunma University School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kurabayashi
authors.forename: S
authors.initials: S
authors.lastname: Miyawaki
authors.forename: H
authors.initials: H
authors.lastname: Murakami
authors.forename: K
authors.initials: K
authors.lastname: Nemoto
authors.forename: M
authors.initials: M
authors.lastname: Sawamura
authors.forename: K
authors.initials: K
authors.lastname: Kubota
authors.forename: T
authors.initials: T
authors.lastname: Naruse
authors.forename: J
authors.initials: J
authors.lastname: Tsuchiya
mesh_terms: D001853:Bone Marrow / Q000473:pathology / Q000648:ultrastructure; D002467:Cell Nucleus / Q000473:pathology / Q000648:ultrastructure*; D004721:Endoplasmic Reticulum / Q000473:pathology / Q000648:ultrastructure; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000648:ultrastructure*; D010950:Plasma Cells / Q000473:pathology / Q000648:ultrastructure
chemical_list: D007145:Immunoglobulin kappa-Chains