[Cells presenting GABA immunoreactivity in the hypothalamus of the cat].
The distribution of GABA-immunoreactive (IR) cells was studied by immunohistochemistry in conjunction with highly specific antiserum GABA in the cat hypothalamus. Colchicine pretreatment made it possible to visualize a large number of labeled cells in the medial preoptic and dorsal hypothalamic areas. In contrast, the ventromedial and anterior hypothalamic nuclei contained only a few labeled cells, and the paraventricular and supraoptic nuclei were devoid of them. A very dense network of GABA-IR presumptive terminals was seen in the ventrolateral posterior hypothalamus where labeled cells could be recognized. The possibility of an involvement of the GABAergic neuronal system in the regulation of sleep-waking cycle is discussed.
Kitahama
K
K
Département de Médecine expérimentale, Faculté de Médecine, I.N.S.E.R.M.-U52, Université Claude-Bernard, Lyon.
Sallanon
M
M
Okamura
H
H
Geffard
M
M
Jouvet
M
M
D000818:Animals; D002415:Cats; D003078:Colchicine / Q000494:pharmacology; D005260:Female; D006651:Histocytochemistry; D007031:Hypothalamus / Q000032:analysis / Q000166:cytology*; D008297:Male; D009474:Neurons / Q000032:analysis*; D014018:Tissue Distribution; D005680:gamma-Aminobutyric Acid / Q000032:analysis*
D005680:gamma-Aminobutyric Acid; D003078:Colchicine
Cellules présentant une immunoréactivité au GABA dans l'hypothalamus du Chat.