title: Experimental Brugia pahangi and B. malayi infections of callitrichid primates.
abstract: The callitrichid primates, Callithrix jacchus jacchus (the marmoset) and Saguinus labiatus (the tamarin) were inoculated with infective larvae of Brugia malayi and B. pahangi. Microfilaraemia at low levels developed in 3 out of 4 C.j. jacchus infected with B. malayi and living or dead adult worms found in all 4. Only one of 4 C.j. jacchus became microfilaraemic (mf + ve) when given B. pahangi and adults were found in two. Of 4 S. labiatus given B. pahangi one became very lightly mf + ve and adults were found in 3. It is concluded that these animals are not suitable hosts for chemotherapeutic experiments.
authors.affiliation: London School of Hygiene and Tropical Medicine, England.
authors.forename: D A
authors.initials: DA
authors.lastname: Denham
authors.forename: R R
authors.initials: RR
authors.lastname: Suswillo
authors.forename: C M
authors.initials: CM
authors.lastname: Hetherington
mesh_terms: D000818:Animals; D002009:Brugia / Q000472:pathogenicity*; D002144:Callithrix / Q000469:parasitology*; D002143:Callitrichinae / Q000469:parasitology*; D004195:Disease Models, Animal; D004198:Disease Susceptibility; D005260:Female; D008297:Male; D012452:Saguinus / Q000469:parasitology*