title: [X-ray and scintigraphic diagnosis of thyroid cancer metastatic to bone].
abstract: Comparative analysis of the results of radio- and scintigraphic investigation of 101 patients with thyroid cancer (TC) metastases to the bones has shown the appropriateness of combined diagnosis at all stages of patients' examination. The use of osteoscintigraphy with 99mTc-phosphates with subsequent x-ray investigation and whole-body scintigraphy with 131I contributes to early and more complete diagnosis of TC skeletal metastases. Iodine accumulation in TC bone metastases depends on the morphological structure of a tumor, the presence of functioning thyroid tissue and the level of iodine in the patient's body at the time of examination. In complete ablation of thyroid tissue and a low iodine level, iodine concentrating TC metastases in the skeleton are detected in 65.8% of patients with follicular cancer, in 41.7% of patients with papillary cancer, and in rare cases of medullary and undifferentiated TC. The results of combined radiological (with 131I) and scintigraphic investigation reflect important aspects in anatomy and function of TC bone metastases and can be used for the objective evaluation of the effectiveness of applied therapy.
authors.forename: V V
authors.initials: VV
authors.lastname: Babushkin
authors.forename: L S
authors.initials: LS
authors.lastname: Zvekotkina
authors.forename: A Z
authors.initials: AZ
authors.lastname: Naumenko
mesh_terms: D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D001842:Bone and Bones / Q000000981:diagnostic imaging; D003131:Combined Modality Therapy; D006801:Humans; D007457:Iodine Radioisotopes; D010710:Phosphates; D011859:Radiography; D013667:Technetium; D017556:Technetium Compounds; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000628:therapy; D014055:Tomography, Emission-Computed; D014915:Whole-Body Counting
chemical_list: D007457:Iodine Radioisotopes; D010710:Phosphates; D017556:Technetium Compounds; C046451:technetium Tc 99m phosphate; D013667:Technetium
vernacular_title: Rentgenologicheskaia i stsintigraficheskaia diagnostika metastazov raka shchitovidnoĭ zhelezy v kosti.