title: Evolving theories of enzyme evolution.
authors.affiliation: Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110-1095.
authors.forename: D L
authors.initials: DL
authors.lastname: Hartl
mesh_terms: D005075:Biological Evolution; D004798:Enzymes / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics; D009154:Mutation; D011110:Polymorphism, Genetic; D013379:Substrate Specificity; D001616:beta-Galactosidase / Q000235:genetics
chemical_list: D004798:Enzymes; D001616:beta-Galactosidase