title: The possibility of a healthy progeny in patients after acute lymphoblastic leukaemia.
abstract: Five patients, cured from acute lymphoblastic leukaemia (ALL), four women and one man, have seven healthy children: four girls and three boys. The children were born in the period from 13 to 25 years since the beginning of the disease and 5 to 16 years after cessation of monotherapy. Age of the children varied from 2 to 13 years. In two patients and in their children an inversion or a partial inversion of the heterochromatic region of chromosome 9 was observed.
authors.forename: R
authors.initials: R
authors.lastname: Rokicka-Milewska
authors.forename: D
authors.initials: D
authors.lastname: Derulska
authors.forename: E
authors.initials: E
authors.lastname: Chmurzyńska-Mróz
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000633:toxicity; D002648:Child; D002675:Child, Preschool; D005260:Female; D005298:Fertility / Q000502:physiology*; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics* / Q000401:mortality; D012098:Reproduction / Q000502:physiology*
chemical_list: D000970:Antineoplastic Agents