Elimination of goat haemoglobin and its complexes with goat haptoglobin from goat and rat circulation.
The rate of elimination from rat and goat circulation of 125I-labelled goat haemoglobin and its complexes with human and goat haptoglobin in goat circulation, was studied. The half-life time t1/2 of haemoglobin in rat circulation was 1.5h, whereas in goat circulation -- 4 h, and was 10 times shorter than t1/2 for its complexes.
Osada
J
J
Chair and Department of Pharmaceutical Biochemistry, Medical Academy, Wroclaw, Poland.
Nowacki
W
W
D000818:Animals; D006041:Goats / Q000097:blood*; D006242:Haptoglobins / Q000378:metabolism*; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D008297:Male; D008657:Metabolic Clearance Rate; D051381:Rats
D006242:Haptoglobins; D006454:Hemoglobins