title: Surgical treatment of Wolff-Parkinson-White syndrome combined with variant angina pectoris.
abstract: Seven patients with coexistent Wolff-Parkinson-White (WPW) syndrome and variant angina pectoris underwent surgical interruption of an accessory atrioventricular conduction pathway. In two of these patients, perioperative coronary artery spasm occurred. One patient had a perioperative myocardial infarction and the other patient treated successfully had no infarction. Nitroglycerin and nifedipine were administered during and following operation in the other 5 patients without perioperative coronary artery spasm. No adverse effect was observed in the intraoperative electrophysiological study. Combined therapy of intravenous nitroglycerin administration and sublingual nifedipine administration are useful in the perioperative management of patients with coexistent WPW syndrome and variant angina pectoris.
authors.affiliation: Department of Surgery (I), Kanazawa University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kawasuji
authors.forename: T
authors.initials: T
authors.lastname: Misaki
authors.forename: K
authors.initials: K
authors.lastname: Mukai
authors.forename: T
authors.initials: T
authors.lastname: Iwa
mesh_terms: D000328:Adult; D000788:Angina Pectoris, Variant / Q000150:complications / Q000601:surgery*; D002304:Cardiac Pacing, Artificial; D004562:Electrocardiography; D005260:Female; D006329:Heart Conduction System / Q000601:surgery*; D006801:Humans; D007430:Intraoperative Care; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000627:therapeutic use; D005996:Nitroglycerin / Q000627:therapeutic use; D014927:Wolff-Parkinson-White Syndrome / Q000150:complications / Q000601:surgery*
chemical_list: D005996:Nitroglycerin; D009543:Nifedipine