Insulin-like growth factor-I in the parenterally fed low birth weight infant.
Postnatal change in insulin-like growth factor-1 (IGF-I) was studied longitudinally in 9 very low birth weight infants (less than 1,200 g, less than 30 weeks at birth) who were receiving 85% or more of their nutrient intake via the parenteral route. There was no apparent relationship between IGF-I, nitrogen intake, energy intake, or nitrogen retention. In 6/9 infants IGF-I decreased with postnatal age. A low IGF-I may reflect the poor nutritional status and growth rate commonly seen in sick preterm infants.
Saini
J R
JR
Department of Child Health, Charing Cross and Westminster Medical School, London, UK.
Morgan
J B
JB
Teale
J D
JD
Kovar
I Z
IZ
D002149:Energy Intake; D005260:Female; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007334:Insulin-Like Growth Factor I / Q000378:metabolism*; D008137:Longitudinal Studies; D008297:Male; D009584:Nitrogen / Q000378:metabolism; D010289:Parenteral Nutrition, Total; D013002:Somatomedins / Q000378:metabolism*
D013002:Somatomedins; D007334:Insulin-Like Growth Factor I; D009584:Nitrogen