title: Lactate and isoproterenol infusions in bulimic patients.
abstract: We compared the responses of bulimic subjects to those of panic disorder patients and normal controls during infusions of sodium lactate and isoproterenol in a double-blind, placebo-controlled study. Four of 8 bulimics infused with lactate had panic attacks. Three of 9 bulimics infused with isoproterenol panicked, and 1 bulimic panicked with a placebo infusion. Although bulimics were less likely than panic disorder patients to panic during provocative infusions, their anxiety levels as measured by a panic description scale were as great. A large portion of the anxiety response in bulimics occurred in those who had concurrent panic attacks.
authors.affiliation: Wayne State University, School of Medicine, Detroit, Mich.
authors.forename: R
authors.initials: R
authors.lastname: Pohl
authors.forename: V K
authors.initials: VK
authors.lastname: Yeragani
authors.forename: R
authors.initials: R
authors.lastname: Balon
authors.forename: H
authors.initials: H
authors.lastname: Lycaki
mesh_terms: D000328:Adult; D001008:Anxiety Disorders / Q000175:diagnosis* / Q000523:psychology; D002032:Bulimia / Q000175:diagnosis* / Q000523:psychology; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D007545:Isoproterenol; D007773:Lactates; D019344:Lactic Acid; D008875:Middle Aged; D010200:Panic / Q000187:drug effects
chemical_list: D007773:Lactates; D019344:Lactic Acid; D007545:Isoproterenol