[Effect of the transplantation of cultured pancreatic islet cell on the status of diabetic microangiopathy].
Investigation of the effect of allo- and xenotransplantation of pancreatic tissue cultures on the hemodynamic indices of 85 patients with diabetes mellitus using ophthalmoscopy, biomicroophthalmoscopy, integral rheography, capillaroscopy and clinical biochemical tests at varying time (from 3 mos to 4 yrs.) showed a gradual improvement of the ophthalmological picture of the fundus of the eye in 58 patients (86%) during the first 9 mos with further stabilization of a process. Lower limb improvement was noted in 18% of the patients, stabilization of a process--in 74%. The improvement of the renal clinico-biochemical indices was noted in 47-67%. Contraindications for beta = culture transplantation were diabetic glomerulosclerosis with stage III chronic renal insufficiency and retinopathy of diabetorenal type.
Danilova
A I
AI
Zubkova
S T
ST
Efimov
A S
AS
Komissarenko
I V
IV
Turchin
I S
IS
D000293:Adolescent; D000328:Adult; D003925:Diabetic Angiopathies / Q000503:physiopathology / Q000601:surgery*; D003928:Diabetic Nephropathies / Q000601:surgery; D005654:Fundus Oculi; D006439:Hemodynamics; D006801:Humans; D016381:Islets of Langerhans Transplantation; D008875:Middle Aged; D009887:Ophthalmoscopy; D014792:Visual Acuity
Vliianie transplantatsii kul'tury ostrovkovykh kletok podzheludochnoĭ zhelezy na sostoianie diabeticheskikh mikroangiopatiĭ.