title: [Atrioventricular block, a complication of radiotherapy of the mediastinum].
abstract: Cardiac complications of mediastinal irradiation usually concern the pericardium, the ventricular myocardium and the coronary arteries. We report the case of a 42-year old woman who experienced a syncopal atrioventricular (AV) block 12 years after irradiation of a mediastinal Hodgkin's lymphoma. Electrophysiological recordings showed infranodal conduction disturbances. A review of the literature yielded only 12 cases of syncopal radiation-induced AV block. This case highlights the risk of syncopal AV blocks occurring a long time after mediastinal irradiation and leading to severe damage of the His bundle and its branches. The presence, as in our patient, of an associated right ventricular outflow tract stenosis confirms the importance and severity of radiation-induced cardiac lesions.
authors.affiliation: Service de cardiologie, Centre hospitalo-universitaire Nord, Marseille.
authors.forename: A
authors.initials: A
authors.lastname: Ebagosti
authors.forename: M
authors.initials: M
authors.lastname: Gueunoun
authors.forename: R
authors.initials: R
authors.lastname: Favre
authors.forename: A
authors.initials: A
authors.lastname: Baralla
authors.forename: P
authors.initials: P
authors.lastname: Farisse
authors.forename: G
authors.initials: G
authors.lastname: Pons
authors.forename: P
authors.initials: P
authors.lastname: Barragan
authors.forename: R
authors.initials: R
authors.lastname: Gerard
authors.forename: S
authors.initials: S
authors.lastname: Levy
mesh_terms: D000328:Adult; D005260:Female; D006327:Heart Block / Q000209:etiology*; D006689:Hodgkin Disease / Q000532:radiotherapy*; D006801:Humans; D008479:Mediastinal Neoplasms / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000150:complications*; D013575:Syncope / Q000209:etiology
vernacular_title: Bloc auriculo-ventriculaire, complication de la radiothérapie du médiastin.