title: Labat lecture. Phantom limbs.
abstract: A phantom limb is universally experienced after a limb has been amputated or its sensory roots have been destroyed. A complete break of the spinal cord also often leads to a phantom body below the level of the break. Furthermore, phantom breasts, genitals and other body areas occur in a substantial number of people after surgical removal or denervation of the body part. The most astonishing feature of a phantom limb (or other body area) is its incredible "reality" to the person. An examination of phantom limb phenomena has led to a new theory. It is proposed that we are born with a widespread neural network--the neuromatrix--for the body-self, which is subsequently modified by experience. The neuromatrix imparts a pattern--the neurosignature--on all inputs from the body, so that experiences of one's own body have a quality of self and are imbued with affective tone and cognitive meaning. The theory is presented with supporting evidence as well as implications for research.
authors.affiliation: Department of Psychology, McGill University, Montreal, Quebec, Canada.
authors.forename: R
authors.initials: R
authors.lastname: Melzack
mesh_terms: D001921:Brain / Q000503:physiopathology*; D006801:Humans; D010146:Pain / Q000503:physiopathology; D010591:Phantom Limb / Q000503:physiopathology*