title: [Complete remission without marrow aplasia phase in a patient with acute promyelocytic leukosis treated with aggressive chemotherapy].
abstract: A patient diagnose of acute promyelocytic leukemia treated with chemotherapy schedule type VAPA. 2 weeks after the administration, there was no response this being the reason to administer a new induction course. 2 weeks after this, a new bone marrow aspiration was performed showing leukemic infiltration with 78% promyelocytes. The clinical situation of the patient did not recommend the addition of more chemotherapy. 10 days later complete remission in bone marrow and blood were demonstrated. The importance of this finding is discussed, complete remission without aplasia, as well as the diagnosis and therapeutic remarks of the case.
authors.forename: E
authors.initials: E
authors.lastname: del Potro Gómez
authors.forename: R
authors.initials: R
authors.lastname: Martínez Martínez
authors.forename: J C
authors.initials: JC
authors.lastname: López Martín
authors.forename: M
authors.initials: M
authors.lastname: Díaz Morfa
authors.forename: J
authors.initials: J
authors.lastname: Díaz Mediavilla
authors.forename: D
authors.initials: D
authors.lastname: Espinos Pérez
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000494:pharmacology / Q000627:therapeutic use*; D001853:Bone Marrow / Q000473:pathology*; D002454:Cell Differentiation / Q000187:drug effects; D003561:Cytarabine / Q000008:administration & dosage / Q000494:pharmacology; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D004317:Doxorubicin / Q000008:administration & dosage / Q000494:pharmacology; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D014411:Neoplastic Stem Cells / Q000187:drug effects; D011239:Prednisolone / Q000008:administration & dosage / Q000494:pharmacology; D012074:Remission Induction; D013997:Time Factors; D014750:Vincristine / Q000008:administration & dosage / Q000494:pharmacology
chemical_list: D003561:Cytarabine; D014750:Vincristine; D004317:Doxorubicin; D011239:Prednisolone
vernacular_title: Remisión completa sin fase de aplasia medular en un paciente con leucosis aguda promielocítica tratado con quimioterapia agresiva.