A case of carmofur-induced leukoencephalopathy--MR images and CT findings.
In a patient with carmofur-induced leukoencephalopathy with a fairly good prognosis, serial MR images demonstrated reversible abnormal signal intensity areas located in the cerebral white matter surrounding the lateral ventricles. These findings suggested that the edematous change together with demyelination of the white matter is important in the pathogenesis underlying carmofur-induced leukoencephalopathy.
Saitoh
H
H
Department of Neurology, School of Medicine, Tokai University, Kanagawa, Japan.
Shinohara
Y
Y
Fujita
H
H
Aoki
Y
Y
Takagi
S
S
D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects; D003110:Colonic Neoplasms / Q000188:drug therapy; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D007968:Leukoencephalopathy, Progressive Multifocal / Q000139:chemically induced* / Q000175:diagnosis / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D014057:Tomography, X-Ray Computed
D000970:Antineoplastic Agents; C017367:carmofur; D005472:Fluorouracil