Safety of the nonionic contrast medium omnipaque in coronary angiography.
The low osmolar nonionic contrast medium Omnipaque was used in 5,339 consecutive coronary angiographies and serious complications were registered. Myocardial infarction occurred in 4 patients, of whom 2 died, and ventricular fibrillation in 1. Cerebral embolism occurred in 11 patients, all of whom survived. The results are compared with those of previous series of coronary angiography with high osmolar ionic media. It is concluded that use of the nonionic medium Omnipaque resulted in a significant reduction of the frequency of serious complications.
Levorstad
K
K
Department of Diagnostic Radiology, National Hospital, University of Oslo, Norway.
Vatne
K
K
Brodahl
U
U
Laake
B
B
Simonsen
S
S
Aakhus
T
T
D000328:Adult; D000368:Aged; D003287:Contrast Media / Q000008:administration & dosage / Q000009:adverse effects; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000209:etiology; D007472:Iohexol / Q000008:administration & dosage / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology; D011446:Prospective Studies; D012449:Safety; D014693:Ventricular Fibrillation / Q000209:etiology
D003287:Contrast Media; D007472:Iohexol