title: Coumamidines, new broad spectrum antibiotics of the cinodine type. I. Discovery, taxonomy of the producing organism and fermentation.
abstract: Coumamidines are water-soluble basic antibiotics related to the glycocinnamoylspermidines. They are produced by a soil isolate designated Saccharopolyspora sp. AB 1167L-65. The coumamidines have broad spectrum activity and were selected in a screen for substances which inhibit Pseudomonas aeruginosa.
authors.affiliation: Anti-infective Research Division, Abbott Laboratories, Abbott Park, Illinois.
authors.forename: M
authors.initials: M
authors.lastname: Jackson
authors.forename: J P
authors.initials: JP
authors.lastname: Karwowski
authors.forename: R J
authors.initials: RJ
authors.lastname: Theriault
authors.forename: W L
authors.initials: WL
authors.lastname: Kohl
authors.forename: P E
authors.initials: PE
authors.lastname: Humphrey
authors.forename: G N
authors.initials: GN
authors.lastname: Sunga
authors.forename: S J
authors.initials: SJ
authors.lastname: Swanson
authors.forename: R M
authors.initials: RM
authors.lastname: Villarreal
mesh_terms: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000494:pharmacology; D001419:Bacteria / Q000145:classification / Q000254:growth & development / Q000378:metabolism* / Q000648:ultrastructure; D003470:Culture Media; D005285:Fermentation; D008855:Microscopy, Electron, Scanning; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D012988:Soil Microbiology
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D003470:Culture Media