[Comparison of virus isolation and antigen enzyme immunoassay in the detection of HIV].
Virus isolation from peripheral blood lymphocytes and antigen detection in serum by ELISA were compared in 75 patients with a serologically confirmed HIV infection. 25 per cent of the lymphocyte cultures were HIV positive, but only 2 of the 14 patients were also antigen positive. In addition, infectious virus was not detected in 15 antigen positive patients, thus revealing only a low degree of correlation between the two assay systems.
Barrett
P N
PN
Immuno AG, Wien.
Dorner
F
F
Stingl
G
G
Heinz
F X
FX
Kunz
C
C
D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology; D004797:Enzyme-Linked Immunosorbent Assay; D006678:HIV / Q000302:isolation & purification*; D015483:HIV Antibodies / Q000032:analysis; D015488:HIV Antigens / Q000032:analysis*; D016655:HIV Core Protein p24; D006679:HIV Seropositivity / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology; D006801:Humans; D012191:Retroviridae Proteins / Q000032:analysis; D013601:T-Lymphocytes / Q000382:microbiology
D015483:HIV Antibodies; D015488:HIV Antigens; D016655:HIV Core Protein p24; D012191:Retroviridae Proteins
Vergleich von Virusisolierung und Antigenenzymimmunoassay zum Nachweis von HIV.