Spontaneous postpartum factor VIII inhibitor development with bleeding into the face and neck.
The coagulopathy caused by factor VIII inhibitor development can cause life-threatening bleeding that may be difficult to manage. Control of the bleeding, medically and surgically, and normalization of factor VIII and inhibitor levels are the goals of treatment; several modes of therapy are available. A case of spontaneous post-partum development of factor VIII inhibitors was presented and discussed.
O'Sullivan
J L
JL
Department of Plastic and Reconstructive Surgery, Rhode Island Hospital, Providence.
Haedicke
G J
GJ
Bevivino
J
J
D000328:Adult; D001778:Blood Coagulation Disorders / Q000209:etiology*; D005169:Factor VIII / Q000037:antagonists & inhibitors*; D005260:Female; D006406:Hematoma / Q000209:etiology; D006801:Humans; D009333:Neck; D006472:Oral Hemorrhage / Q000209:etiology*; D011247:Pregnancy; D011644:Puerperal Disorders / Q000097:blood*
D005169:Factor VIII