[Studies on the virulence in the guinea pig of tuberculosis bacilli isolated from patients with pulmonary tuberculosis before treatment in Shanghai].
The virulence in guinea-pig of 44 tubercle bacilli cultures from patients of tuberculosis before treatment in Shanghai and 26 from Tokyo has been studied for comparison. The results showed that the virulence of tubercle bacilli from Shanghai was lower than that from Tokyo. The difference was statistically significant (P less than 0.01). Among the 44 cultures from Shanghai high virulence accounted for 54.5%, low virulence 15.9% and middle virulence 29.5% whereas for the cultures from Tokyo high virulence accounted for 96.2% and middle virulence 3.8%.
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D000818:Animals; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D008297:Male; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification / Q000472:pathogenicity*; D013183:Sputum / Q000382:microbiology; D014397:Tuberculosis, Pulmonary / Q000382:microbiology*; D014774:Virulence