[Present status of surgical adjuvant chemotherapy of gastric cancer].
We need to come back to the origin of chemotherapy in the research of post-operative adjuvant chemotherapy for stomach cancer. We need to establish good regimens of adjuvant chemotherapy, which certainly work in advanced stomach cancer. If chemotherapeutic regimens are modified to use them as adjuvant therapies, we should follow the principle rules of chemotherapy. One of measures which we can take is to conduct randomised controlled studies in patients at high risk to compare best possible regimens which are currently available. On these studies, it is recommended that patients are first stratified by prognostic factors, followed by randomization.
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Dept. of Surgery, Osaka University.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage*; D011182:Postoperative Care; D011379:Prognosis; D011897:Random Allocation; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000601:surgery
D008937:Mitomycins; D016685:Mitomycin; D005472:Fluorouracil