title: [Changes in indicators of nonspecific humoral immunity in carriers of N. meningitidis].
abstract: The aim of the work was to assess the immunity response of the macroorganism to "sound" meningococcal carriership in relation to its length. Furthermore the author wanted to assess the state of immunity changes during the inter-epidemic period. Although the differences in the immunity response in different groups are not significant, they exist and correlate with data reported in the literature. The most important finding is that during the period of the maximum drop of IgG and IgM antibodies there is an increase of the IgA class of immunoglobulins and the C3 component of complement. This correlates with the maximum number of carriers in the investigated group. Despite existing described changes of non-specific humoral immunity, the author considers specific, in particular collective immunity which determines the epidemic process of meningococcal infections, decisive for the development of meningococcal carriership.
authors.forename: E
authors.initials: E
authors.lastname: Tomásik
mesh_terms: D002353:Carrier State / Q000276:immunology*; D003165:Complement System Proteins / Q000032:analysis; D006801:Humans; D007113:Immunity, Innate; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D008585:Meningitis, Meningococcal / Q000276:immunology*; D009345:Neisseria meningitidis / Q000276:immunology
chemical_list: D007136:Immunoglobulins; D003165:Complement System Proteins
vernacular_title: Zmeny niektorých ukazovatel'ov nespecifickej humorálnej imunity pri nosicstve N. meningitidis.