Chondroitinase C activity of Streptococcus intermedius.
Chondroitin 6-sulfate depolymerizing activity was examined in the culture supernatant of Streptococcus intermedius ATCC 27335. 2-Acetamido-2-deoxy-3-O-(beta-D-gluco-4-enepyranosyluronic acid)-6-O-sulfo-D-galactose was split from the substrate. The enzyme(s) was not active upon chondroitin 4-sulfate or dermatan sulfate, which indicated that the enzyme responsible for the depolymerization is chondroitinase C.
Hibi
E
E
Department of Microbiology, School of Dentistry, Aichi-Gakuin University, Nagoya, Japan.
Osano
E
E
Fujii
Y
Y
Moriyama
T
T
D002808:Chondroitin Lyases / Q000378:metabolism*; D002809:Chondroitin Sulfates; D002810:Chondroitinases and Chondroitin Lyases / Q000378:metabolism*; D003871:Dermatan Sulfate; D013291:Streptococcus / Q000201:enzymology*; D013379:Substrate Specificity
D003871:Dermatan Sulfate; D002809:Chondroitin Sulfates; D002808:Chondroitin Lyases; D002810:Chondroitinases and Chondroitin Lyases