[Activation of Rickettsiae prowazekii in the composition of immune complexes by antiglobulin serum].
The antiglobulin serum (AGS) against spotted fever immunoglobulin of guinea pigs was studied for its effect on the in vitro created immune complex rickettsiae + antibody in experiments using the procedure of laboratory cultivation of Rickettsiae prowazekii according to Weigl. The biological activity of the pathogen is shown to be restored under the action of AGS. This fact may be used for detecting the antigen + antibody complexes in case of the spotted fever and for studying their role in the relapsive forms of the disease.
Klimchuk
N D
ND
Frolov
A F
AF
Shablovskaia
E A
EA
Sagaĭdakovskiĭ
N N
NN
Gavrilov
S V
SV
D000818:Animals; D000888:Antibodies, Anti-Idiotypic / Q000276:immunology*; D000936:Antigen-Antibody Complex / Q000276:immunology*; D008003:Phthiraptera / Q000382:microbiology*; D012283:Rickettsia prowazekii / Q000276:immunology*
D000888:Antibodies, Anti-Idiotypic; D000936:Antigen-Antibody Complex
Aktivatsiia rikketsiĭ provacheka v sostave immunnykh kompleksov antiglobulinovoĭ syvorotkoĭ.