Reversal of an abnormal free fatty acid response to emotional stress in a diabetic adolescent using a portable insulin-infusion pump.
Repeated episodes of ketoacidosis in some juvenile diabetics has been associated with an abnormal rise in circulating free fatty acids (FFA) following emotional stress. Reversal of this phenomenon occurred after treatment with a portable insulin infusion pump (PIIP). Following initiation of PIIP treatment, this abnormal rise in FFA secretion was eliminated, as were the patient's episodes of ketoacidosis. We believe that PIIP treatment should be considered in the poorly controlled compliant diabetic patient.
Noto
R A
RA
Department of Pediatrics, North Shore University Hospital, Cornell Medical College, Valhalla, NY.
Kaplan
S
S
Tames
S M
SM
Matthews
M
M
Ginsberg
L
L
Lifshitz
F
F
D000293:Adolescent; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy*; D016883:Diabetic Ketoacidosis / Q000209:etiology; D005230:Fatty Acids, Nonesterified / Q000378:metabolism*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007332:Insulin Infusion Systems; D008016:Life Change Events; D013315:Stress, Psychological / Q000097:blood*
D005230:Fatty Acids, Nonesterified