[Vaccination of mice against murine coccidiosis by ingestion of surface proteins of Eimeria falciformis incorporated in liposomes].
Proteins are released from the surface of sporozoites of Eimeria falciformis during their in vitro incubation in a detergent solution. Some of these proteins reacted with antibodies from infected mice and specifically stimulated the proliferation of mesenteric lymph node cells of these mice. Oral immunization of mice with liposome encapsulated sporozoite surface antigens protected mice against a challenge infection. Two proteins (M.W. 27 and 180 K) induced an antibody synthesis in these vaccinated mice.
Rhalem
A
A
Station de Recherches de Virologie et d'Immunologie, I.N.R.A., Centre de Recherches de Jouy-en-Josas, Domaine de Vilvert.
Bekhti
K
K
Bourdieu
C
C
Luffau
G
G
Péry
P
P
D000284:Administration, Oral; D000818:Animals; D000953:Antigens, Protozoan / Q000008:administration & dosage*; D000954:Antigens, Surface / Q000008:administration & dosage*; D003048:Coccidiosis / Q000517:prevention & control*; D004337:Drug Carriers; D004539:Eimeria / Q000276:immunology*; D008081:Liposomes; D051379:Mice; D008807:Mice, Inbred BALB C; D014611:Vaccination
D000953:Antigens, Protozoan; D000954:Antigens, Surface; D004337:Drug Carriers; D008081:Liposomes
Vaccination de la souris contre la coccidiose murine par ingestion de protéines de surface d'Eimeria falciformis incorporées dans des liposomes.