title: [Canthaxanthin retinopathy and macular pucker--clinical picture and ultrastructural findings of macular pucker].
abstract: Canthaxanthine retinopathy is a crystalline retinopathy that follow oral ingestion of canthaxanthine-containing drugs. We describe the clinical course of a patient with canthaxanthine retinopathy and preexisting idiopathic macular pucker over a period of 2.5 years. Light microscopic investigation of the macular pucker revealed a fibrocellular membrane containing granular, birefringent material and vacuoles within the cells of the membrane resulting from canthaxanthine deposits in the epiretinal membrane. Long-term follow-up shows a slight, but significant, reduction of the retinal crystals.
authors.forename: S
authors.initials: S
authors.lastname: Bopp
authors.forename: E
authors.initials: E
authors.lastname: el-Hifnawi
authors.forename: H
authors.initials: H
authors.lastname: Laqua
mesh_terms: D000368:Aged; D016644:Canthaxanthin; D002338:Carotenoids / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D003460:Crystallization; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008266:Macula Lutea / Q000187:drug effects; D008269:Macular Edema / Q000139:chemically induced*; D012164:Retinal Diseases / Q000139:chemically induced*
chemical_list: D002338:Carotenoids; D016644:Canthaxanthin
vernacular_title: Canthaxanthin-Retinopathie und Macula Pucker--klinisches Bild und ultrastrukturelle Befunde des Macula Pucker.