Peripheral blood morphology: could it be of value in prediction and diagnosis of renal allograft rejection?
Forty kidney transplant recipients were examined twice weekly during the first postoperative month and once weekly during the second month and whenever graft rejection was suspected. Fine-needle aspiration biopsies (FNAB) of the graft and examination of the peripheral blood for changes in different cell population were performed. Furthermore, to study the predictive value of peripheral blood examination for diagnosis of graft rejection another 30 patients were subjected to daily peripheral blood examination after transplantation during the first postoperative month. The sensitivity of peripheral blood examination to diagnose rejection was found to be 53.8% and the specificity was 81% while the predictive value was 75%. We conclude that peripheral blood examination is an additional beneficial test for diagnosis of graft rejection.
Moustafa
F E
FE
Urology and Nephrology Center, University of Mansoura, Egypt.
Sobh
M A
MA
Ghoneim
M A
MA
D001772:Blood Cell Count; D001773:Blood Cells / Q000473:pathology*; D003951:Diagnostic Errors; D006084:Graft Rejection; D006801:Humans; D016030:Kidney Transplantation