title: Value of Humphrey perimetry in the detection of early chloroquine retinopathy.
abstract: Various forms of perimetry are used to confirm Chloroquine retinopathy diagnosed by Amsler grid testing. Little is known about the value of using a red target generated statically. The purpose of this study was to determine the sensitivity and specificity of both red and white perimetry using program 10-2 on the Humphrey automated perimeter. Sixty-nine eyes were tested in total. Fifty eyes were from patients with known early Chloroquine retinopathy with abnormal Amslers. Red perimetry was 91.3% sensitive and 57.8% specific for Chloroquine retinopathy. White perimetry was 78% sensitive and 84% specific for this condition. In conclusion, red Humphrey perimetry was highly sensitive but not highly specific for Chloroquine retinopathy.
authors.affiliation: Department of Ophthalmology, University of Toronto, Ontario.
authors.forename: M
authors.initials: M
authors.lastname: Easterbrook
authors.forename: G
authors.initials: G
authors.lastname: Trope
mesh_terms: D000368:Aged; D002738:Chloroquine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D011379:Prognosis; D012164:Retinal Diseases / Q000139:chemically induced / Q000175:diagnosis*; D012680:Sensitivity and Specificity; D058609:Visual Field Tests / Q000379:methods*; D014794:Visual Fields / Q000187:drug effects
chemical_list: D002738:Chloroquine