title: [Therapeutic efficacy of the principal antitubercular drugs: an evaluation by antibiogram].
abstract: Pulmonary and extrapulmonary tuberculosis is still encountered in clinical practice, sometimes in forms that are difficult to categorize nosographically. In this study, the therapeutic efficacy of the 6 main antitubercular drugs (rifampicin, streptomycin, isoniazide, ethambutol, kanamycin, para-aminosalicylic acid) in 20 patients with early TB of the lungs was assessed on the basis of antibiogram findings. Para-aminosalicylic acid was found to be the least effective; isoniazide, rifampicin and streptomycin were reasonably so; both kanamycin and ethambutol were extremely effective.
authors.affiliation: Divisione di Medicina Generale, Ospedale Civile, Novi Ligure.
authors.forename: L G
authors.initials: LG
authors.lastname: Cremonte
authors.forename: E
authors.initials: E
authors.lastname: Mantellini
mesh_terms: D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002675:Child, Preschool; D004353:Drug Evaluation, Preclinical; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000187:drug effects*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000995:Antitubercular Agents
vernacular_title: Efficacia terapeutica dei principali farmaci antitubercolari: valutazione mediante antibiogramma.