title: The effect of fluoride drop administration on dental caries increment--a longitudinal study.
abstract: The effect of fluoride drop supplementation was investigated in a longitudinal study initiated in 1980. The def-t and DMF-T indices were used to estimate the incremental caries rate of the deciduous and first molars of 211 children aged 7-8 and 9.5-10.5 years. No statistically significant differences between the experimental and control def-t and DMF-T scores were found after 3 years. The incremental caries rate of the deciduous dentition of the experimental group was found to be significantly lower than that of the control group (def-t = 0.61 and 1.07 respectively), whereas the difference in the caries increments of the first molars was not significant (DMF-T = 1.62 in both groups). It is estimated that the efficacy was due to the long-term cariostatic effect of the topically acting fluoride on the erupting primary dentition, whereas the permanent dentition (first molars) had already completed calcification of the crown, but had not erupted at initiation of the study. It was estimated that the most effective cariostatic benefits would be apparent in the late erupting teeth of this study group.
authors.affiliation: Hebrew University, Jersualem, Israel.
authors.forename: J
authors.initials: J
authors.lastname: Mann
authors.forename: E
authors.initials: E
authors.lastname: Horesh
authors.forename: F
authors.initials: F
authors.lastname: Ran
authors.forename: I
authors.initials: I
authors.lastname: Gedalia
mesh_terms: D002648:Child; D002675:Child, Preschool; D004245:DMF Index; D003731:Dental Caries / Q000517:prevention & control*; D006801:Humans; D008137:Longitudinal Studies; D008963:Molar; D012969:Sodium Fluoride / Q000008:administration & dosage* / Q000493:pharmacokinetics; D014074:Tooth Calcification / Q000187:drug effects; D014078:Tooth Eruption; D014094:Tooth, Deciduous
chemical_list: D012969:Sodium Fluoride