Sites of origin of growth hormone-releasing factor-containing neurons projecting to the stalk-median eminence of the rat.
The topographical location of neurons containing GRF which project to the median eminence were studied with immunofluorescence for GRF in combination with the retrograde transport of True blue. After the injection of True blue into the median eminence, retrogradely-labeled GRF neurons were identified in the arcuate nucleus and the lateral basal hypothalamus. GRF neurons in the perifornical area contained no positive dye. We concluded that the location of neurons containing hypophysiotrophic GRF are confined within the arcuate nucleus and the lateral basal hypothalamus.
Niimi
M
M
Department of Clinical Laboratory, Kagawa Medical School, Japan.
Takahara
J
J
Sato
M
M
Kawanishi
K
K
D000344:Afferent Pathways / Q000033:anatomy & histology* / Q000166:cytology; D000818:Animals; D001111:Arcuate Nucleus of Hypothalamus / Q000033:anatomy & histology* / Q000166:cytology; D005455:Fluorescent Antibody Technique; D013007:Growth Hormone-Releasing Hormone / Q000032:analysis*; D007031:Hypothalamus / Q000033:anatomy & histology* / Q000166:cytology; D008297:Male; D008473:Median Eminence / Q000033:anatomy & histology* / Q000166:cytology; D009474:Neurons / Q000166:cytology / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains
D013007:Growth Hormone-Releasing Hormone