title: Sex in flies: the splice of life.
abstract: The discovery that the primary transcripts of many genes are processed to produce more than one kind of messenger RNA focuses attention on the control of RNA processing as a developmental regulatory mechanism. In the fruit-fly Drosophila melanogaster, differential splicing of a hierarchy of regulatory genes determines sex, and thus the molecular biology of sex determination in the fruit-fly may lead to insights into the mechanisms by which alternative splicing is regulated.
authors.affiliation: Department of Biological Sciences, Stanford University, California 94305.
authors.forename: B S
authors.initials: BS
authors.lastname: Baker
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D005809:Genes, Regulator; D008297:Male; D012326:RNA Splicing; D012732:Sex Determination Analysis