Positron emission tomography with 68-Ga-EDTA and computed tomography in patients with subarachnoid haemorrhage.
26 patients with subarachnoid haemorrhage (SAH) were investigated with 68-Ga-EDTA and positron emission tomography (PET) in order to evaluate the presence of a blood brain barrier (BBB) disturbance. Only one patient showed a BBB disruption. It is suggested that increased levels of substances with higher molecular weight than 68-Ga-EDTA in the cerebrospinal fluid (CSF) are the result of a change in the metabolism of the CSF and the brain tissue caused by a SAH.
von Holst
H
H
Department of Neurosurgery, Karolinska Hospital, Stockholm, Sweden.
Ericson
K
K
Edner
G
G
D000328:Adult; D000368:Aged; D001812:Blood-Brain Barrier; D004492:Edetic Acid; D005260:Female; D005710:Gallium Radioisotopes; D006801:Humans; D008297:Male; D008875:Middle Aged; D013345:Subarachnoid Hemorrhage / Q000000981:diagnostic imaging / Q000503:physiopathology*; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed
D005710:Gallium Radioisotopes; D004492:Edetic Acid