[Morphological evaluation of tissue and cellular components of the corpus striatum, globus pallidus and substantia nigra in 7-day-old rats].
The aim of the study was the morphometric evaluation of tissue and cell composition of brain structures which are involved into transplantation in experimental model of parkinsonism in the rat-substantia nigra as the implanted structure and caudate-putamen as the host structure into which the graft is placed. Three parts of caudate-putamen (anterior, medial and posterior), three parts of substantia nigra (compact, reticular and lateral) as well as pallidum were investigated in 7-day-old rat. It was found that the density of nerve cells is highest in medial part (2236/l mm2), lower in anterior part (2129/1 mm2) and the lowest in posterior one (1842/1 mm2). The number of giant neurons in relation to the rest of neurons in anterior, medial and posterior parts of caudate-putamen was 1:268, 1:147 and 1:545 respectively. This indicates that the numbers of complexes formed by giant neurons with other neurons vary depending on the area of this brain structure. The zonal differences in distribution and size of neurons in caudate-putamen should be taken in account in qualitative and quantitative studies.
Wegiel
J
J
Zakład Neuropatologii, Instytutu Psychiatrii i Neurologii, Warszawa.
Medyńska
E
E
Dziedziak
W
W
Szirkowiec-Gmurczyk
W
W
Dymecki
J
J
D000367:Age Factors; D000818:Animals; D001699:Biometry; D002452:Cell Count; D002454:Cell Differentiation; D003342:Corpus Striatum / Q000166:cytology*; D005917:Globus Pallidus / Q000166:cytology; D008297:Male; D009474:Neurons / Q000166:cytology*; D051381:Rats; D011919:Rats, Inbred Strains; D013378:Substantia Nigra / Q000166:cytology*
Morfologiczna ocena składników tkankowych i komórkowych prazkowia, gałki bladej i istoty czarnej szczura 7-dniowego.