[Changes in the prolactin level under the effect of pulsatile infusion of gonadotropin releasing hormone].
Plasma prolactin levels were measured in 18 GnRH loading tests and, in 24 cycles involving treatment with GnRH. During 17 GnRH loading tests the prolactin levels production remained virtually unchanged, the individual GnRH pulses not raising the prolactin level. In one case the GnRH loading test led to a considerable rise in prolactin level, which is considered to be a pathological prognostic sign as concerns subsequent GnRH treatment. During unsuccessful pulsatile GnRH treatment, the prolactin secretion in monotonous, while treatment resulting in ovulation, even in hyperprolactinaemia cases, is accompanied by higher prolactin levels in the preovulation and luteal periods than in the early follicular phase.
Koloszár
S
S
Bártfai
G
G
Sas
M
M
D000328:Adult; D000568:Amenorrhea / Q000097:blood / Q000188:drug therapy*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D005498:Follicular Phase; D006801:Humans; D006966:Hyperprolactinemia / Q000097:blood / Q000188:drug therapy; D007262:Infusions, Intravenous / Q000379:methods; D007986:Luteinizing Hormone / Q000097:blood; D008597:Menstrual Cycle / Q000187:drug effects; D010906:Pituitary Hormone-Releasing Hormones / Q000008:administration & dosage* / Q000494:pharmacology; D011388:Prolactin / Q000096:biosynthesis / Q000097:blood*; D011673:Pulsatile Flow
D010906:Pituitary Hormone-Releasing Hormones; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
Prolactin-szint változás gonadotropin releasing hormon pulzatorikus infúziója során.