title: Arthropathy associated with Brucella abortus strain 19 vaccination in cattle. II. Experimental studies.
abstract: Attempts to reproduce in calves the arthropathy associated with Brucella abortus strain 19 (S19) vaccination by direct intra-articular injection of S19 or virulent Brucella cells were unsuccessful. Intra-articular injection of rabbits and a calf with immune complexes isolated from the synovial fluid of a field case produced clinical and histological signs of arthropathy accompanied by the development of rheumatoid factor.
authors.forename: M J
authors.initials: MJ
authors.lastname: Corbel
authors.forename: F A
authors.initials: FA
authors.lastname: Stuart
authors.forename: R A
authors.initials: RA
authors.lastname: Brewer
authors.forename: M
authors.initials: M
authors.lastname: Jeffrey
authors.forename: R
authors.initials: R
authors.lastname: Bradley
mesh_terms: D000818:Animals; D000936:Antigen-Antibody Complex / Q000032:analysis; D002004:Brucella Vaccine / Q000009:adverse effects*; D002003:Brucella abortus / Q000276:immunology*; D002417:Cattle; D002418:Cattle Diseases / Q000209:etiology* / Q000276:immunology; D007592:Joint Diseases / Q000209:etiology / Q000276:immunology / Q000662:veterinary*; D007794:Lameness, Animal / Q000209:etiology / Q000276:immunology; D011817:Rabbits; D012217:Rheumatoid Factor / Q000032:analysis; D013582:Synovial Fluid / Q000276:immunology; D013583:Synovial Membrane / Q000276:immunology / Q000473:pathology; D014611:Vaccination / Q000662:veterinary
chemical_list: D000936:Antigen-Antibody Complex; D002004:Brucella Vaccine; D012217:Rheumatoid Factor