title: Clinical and biological features in the 12 months preceding onset of AIDS in HIV-infected subjects.
abstract: Biological markers of HIV infection were studied in 17 asymptomatic HIV seropositive subjects in the 12 months preceding the onset of the disease. No single marker of HIV infection preceded the development of AIDS. Therefore, the clinical care of asymptomatic seropositive subjects should include a number of tests to evaluate HIV activity and immune suppression.
authors.affiliation: Institut National de Transfusion Sanguine, Paris, France.
authors.forename: J J
authors.initials: JJ
authors.lastname: Lefrere
authors.forename: A M
authors.initials: AM
authors.lastname: Courouce
authors.forename: P
authors.initials: P
authors.lastname: Lambin
authors.forename: J M
authors.initials: JM
authors.lastname: Fine
authors.forename: C
authors.initials: C
authors.lastname: Doinel
authors.forename: C
authors.initials: C
authors.lastname: Salmon
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis / Q000276:immunology*; D000328:Adult; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis; D015331:Cohort Studies; D005260:Female; D015483:HIV Antibodies / Q000032:analysis; D015488:HIV Antigens / Q000276:immunology; D016655:HIV Core Protein p24; D006679:HIV Seropositivity; D006801:Humans; D008297:Male; D008875:Middle Aged; D010455:Peptides / Q000276:immunology; D012191:Retroviridae Proteins / Q000032:analysis / Q000276:immunology; D013997:Time Factors; D054301:gag Gene Products, Human Immunodeficiency Virus
chemical_list: D000945:Antigens, Differentiation, T-Lymphocyte; C052407:HGP-30 peptide, Human immunodeficiency virus-1; D015483:HIV Antibodies; D015488:HIV Antigens; D016655:HIV Core Protein p24; D010455:Peptides; D012191:Retroviridae Proteins; D054301:gag Gene Products, Human Immunodeficiency Virus