Estradiol stimulates cadherin expression in rat granulosa cells.
We have investigated the ability of hormones to modulate cadherin expression by differentiating cells. Immunocytochemical and immunoblot techniques were employed to analyze the effects of estradiol and follicle-stimulating hormone on cadherin expression in rat granulosa cells. Estradiol was shown to stimulate the expression of cadherin by these cells. This is the first report of a hormone regulating the levels of cadherin in differentiating cells.
Blaschuk
O W
OW
Department of Surgery, McGill University, Royal Victoria Hospital, Montreal, Quebec, Canada.
Farookhi
R
R
D000595:Amino Acid Sequence; D000818:Animals; D015153:Blotting, Western; D015820:Cadherins / Q000378:metabolism*; D002449:Cell Aggregation / Q000187:drug effects; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D005455:Fluorescent Antibody Technique; D005640:Follicle Stimulating Hormone / Q000494:pharmacology; D006107:Granulosa Cells / Q000166:cytology / Q000378:metabolism*; D008969:Molecular Sequence Data; D051381:Rats
D015820:Cadherins; D004958:Estradiol; D005640:Follicle Stimulating Hormone