[The importance of magnesium in orthopedics. VI. The importance of magnesium in the treatment of ectopic calcification and ossification].
In a five-year investigation the authors demonstrate their results with Mg treatment in 54 patients with ectopic calcifications and ossifications. Based on the results of experimental work, where the inhibiting action of Mg ions on calcium phosphate precipitation was proved in vitro as well as in vivo, the authors treated by means of local MgSO4 injections and oral administration of Mg lactate 17 patients with ossifying myositis, 16 with calcareal bursitis, 4 patients with paraosteoarthropathy of the elbow after craniocerebral injuries, 6 calcifications of the hip joint after operations and 5 calcifications in the insertions of tendons and ligaments. In all instances diminution to complete disappearance of the calcificates and ossificates was observed. The authors achieved also very favourable functional results. In the majority of patients the mobility in adjacent joints was restored. Clinical experience indicates that Mg prevents the development or suppresses further growth of ectopic calcifications and ossifications. During the formation of the ossificate, which is still immature, Mg causes diminution and sometimes complete absorption of the immature bone.
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D000293:Adolescent; D000328:Adult; D002114:Calcinosis / Q000188:drug therapy*; D002648:Child; D005260:Female; D006801:Humans; D008274:Magnesium / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009999:Ossification, Heterotopic / Q000188:drug therapy*
D008274:Magnesium
Význam magnézia v ortopedii. Cást VI. Význam magnézia v lécbĕ ektopickych kalcifikací a osifikací.