Inhibitory effect of ethanol and acetaldehyde on the amidolytic activity of trypsin and chymotrypsin.
Ethanol and in higher degree acetaldehyde displayed inhibitory effect directed against amidolytic activity of trypsin and chymotrypsin. The decrease of the activity of both enzymes is related to the concentration of these compounds. The rate of inhibition of amidolytic activity of chymotrypsin with both reagents is more evident in comparison to trypsin.
Skrzydlewska
E
E
Department of Instrumental Analysis, Bialystok, Poland.
Worowski
K
K
Zakrzewska
I
I
Prokopowicz
J
J
Puchalski
Z
Z
Piotrowski
Z
Z
D000079:Acetaldehyde / Q000494:pharmacology*; D002918:Chymotrypsin / Q000037:antagonists & inhibitors*; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D014361:Trypsin Inhibitors / Q000494:pharmacology*
D014361:Trypsin Inhibitors; D000431:Ethanol; D002918:Chymotrypsin; D000079:Acetaldehyde