title: Epithelial differentiation in Drosophila pupae.
abstract: The construction of cell hairs on the wings in developing pupae of Drosophila provides a unique system for studies of the regulation of differentiation in the absence of cell division. Early steps in hair construction are the extrusion of cell hairs and the deposition of the external impervious layer called "cuticulin." Some properties of six of the most abundant proteins that are present during the early stages of hair construction are described. These proteins make up about 40% of the total protein of the preparation.
authors.affiliation: Division of Biology, California Institute of Technology, Pasadena.
authors.forename: H K
authors.initials: HK
authors.lastname: Mitchell
authors.forename: N S
authors.initials: NS
authors.lastname: Petersen
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D004331:Drosophila melanogaster / Q000254:growth & development*; D004847:Epithelial Cells; D004848:Epithelium / Q000648:ultrastructure; D008970:Molecular Weight; D009024:Morphogenesis; D014176:Protein Biosynthesis; D011506:Proteins / Q000302:isolation & purification; D011679:Pupa; D014921:Wings, Animal
chemical_list: D011506:Proteins