title: [Vibration-induced inactivation of insulin].
abstract: A case of diabetic ketoacidosis precipitated by employment of flocculated, and thus inactivated, insulin is presented. The flocculation is presumed to have been produced by vibrations which are presumed to make slow-action insulin form insoluble fibrils at room temperature. This mechanism is recognized in rapid-action insulin.
authors.forename: B
authors.initials: B
authors.lastname: Mathiassen
mesh_terms: D000328:Adult; D016883:Diabetic Ketoacidosis / Q000209:etiology; D004355:Drug Stability; D006801:Humans; D007328:Insulin / Q000008:administration & dosage; D008297:Male; D014732:Vibration
chemical_list: D007328:Insulin
vernacular_title: Vibrationsinduceret insulin-inaktivering.