[Characteristics of the isovolumic relaxation period in dilated cardiomyopathy].
The duration of isovolumic relaxation (IR) was used in order to analyze several aspects of diastolic function in patients with dilated cardiomyopathy (DC). This period as measured from the aortic closure sound (A2 on phonocardiogram) to the opening of the mitral valve (on echocardiogram) was determined in 14 patients with DC and compared with findings in 10 normal volunteers (N). Heart rate (HR) and blood pressure (BP) were similar in both groups. The duration of IR was significantly increased in DC (72 ms +/- 6.3 ns) compared with N (41.6 ms +/- 2.8 ns; p less than 0.01). These data suggest that the prolongation in IR may result from alterations in ventricular relaxation.
Escudero
E M
EM
Plastino
J A
JA
Puig
S P
SP
Chiabaut
J
J
D000328:Adult; D000368:Aged; D001794:Blood Pressure; D002311:Cardiomyopathy, Dilated / Q000503:physiopathology*; D006339:Heart Rate; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D009200:Myocardial Contraction
Características del periódo de relajación isovolúmica en la miocardiopatía dilatada.