title: [Effects of dysbacteriosis and impairment of immunity formation in the early neonatal period on morbidity of children during the 1st year of life and ways of its reduction].
abstract: The catamnesis of 124 infants has been studied in the course of 12 months by means of questionnaires. Dysbacteriosis that occur in the early neonatal period produce an unfavourable effect on the immunity establishment and increase the disease incidence among the neonates. Moreover, dysbacteriosis may later result in the impairment of the formation of tolerance to food antigens supplied to the gastrointestinal tract. The carriership of Staphylococcus aureus in the fauces occurring in the presence of the decreased characteristics of local defence and phagocytic system of the newborn favours an increase of the disease incidence in the babies as well as the formation of the chronic foci of infection in the future. Prevention of dysbacteriosis of the early neonatal period by means of the use of biopreparations, particularly of pure cultures of Lactobacillus acidophilus does not only reduce the disease incidence in children of the first year of life but also improves on the whole their health status.
authors.forename: L I
authors.initials: LI
authors.lastname: Chernyshova
mesh_terms: D000367:Age Factors; D001424:Bacterial Infections / Q000517:prevention & control*; D006304:Health Status; D006801:Humans; D007223:Infant; D007231:Infant, Newborn / Q000276:immunology* / Q000382:microbiology*; D007779:Lactobacillus acidophilus
vernacular_title: Vliianie disbakterioza i narusheniia stanovleniia immuniteta v rannem neonatal'nom periode na zabolevaemost' deteĭ pervogo goda zhizni i puti ee snizheniia.