Relaxin in the male.
Relaxin, a hormone usually associated with pregnancy, has been found in the semen plasma of many species. The prostate gland appears to be a source of relaxin. Relaxin stimulates sperm motility from suboptimal samples and increases sperm penetration into oocytes. Thus, relaxin may be an effective therapeutic agent in male infertility.
Weiss
G
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Department of Obstetrics and Gynecology, UMDNJ-New Jersey Medical School, Newark 07103.
D000818:Animals; D005260:Female; D005303:Fertility Agents, Male / Q000494:pharmacology*; D006801:Humans; D008297:Male; D009865:Oocytes / Q000187:drug effects; D012065:Relaxin / Q000494:pharmacology / Q000502:physiology*; D013081:Sperm Motility / Q000187:drug effects*; D013084:Sperm-Ovum Interactions / Q000187:drug effects
D005303:Fertility Agents, Male; D012065:Relaxin