title: [Conservative treatment of malignant liver tumors].
abstract: Conservative treatment was carried out in 119 cases of hepatic malignancy (primary cancer--36 and metastatic tumors--83). Radiation therapy using a Rokus-M installation or a Saturn linear accelerator was performed in 26 cases, chemoradiation treatment--14 and cytostatic therapy alone--in 79 patients. Single focal dose used was 2 Gy, while total dose was as high as 51-70 Gy in cases receiving radiation alone and 35-40 Gy in the combined therapy group. Various combinations of carminomycin, bleomycin, cisplatinum, adriamycin, 5-fluorouracil, allopurinol and cyclophosphamide were employed. Radiation and chemoradiation treatment proved effective in 67.5% of cases. Mean survival time for patients suffering primary cancer was 15.8 +/- 4.3 months, and for those with metastatic tumor--8.3 +/- 1.6 months. Remission was registered in 14, while stabilization--in 31 out of 79 patients who had received chemotherapy. The symptomatic effect was observed in 38%.
authors.forename: D V
authors.initials: DV
authors.lastname: Komov
authors.forename: A I
authors.initials: AI
authors.lastname: Barkanov
authors.forename: E M
authors.initials: EM
authors.lastname: Roshchin
mesh_terms: D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000532:radiotherapy* / Q000556:secondary; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D010315:Particle Accelerators; D011879:Radiotherapy Dosage; D005641:Tegafur / Q000627:therapeutic use
chemical_list: D005641:Tegafur; D005472:Fluorouracil; D008727:Methotrexate
vernacular_title: Konservativnoe lechenie zlokachestvennykh opukholeĭ pecheni.