Connective tissue reaction to buffered and unbuffered glutaraldehyde.
The dorsal skin of 18 healthy Sprague-Dawley rats was used to investigate the reaction of connective tissue to buffered and unbuffered glutaraldehyde. Both the agents produced well-circumscribed lesions that underwent resolution within 30 days. Observation also shows that 2.0% buffered and unbuffered glutaraldehyde maintained a relatively inflammation-free status in connective tissue.
Meon
R
R
Department of Children's Dentistry, Faculty of Dentistry, University of Malaya.
D000447:Aldehydes / Q000494:pharmacology*; D000818:Animals; D002021:Buffers; D003238:Connective Tissue / Q000187:drug effects* / Q000473:pathology; D004487:Edema / Q000473:pathology; D005976:Glutaral / Q000008:administration & dosage / Q000494:pharmacology*; D007249:Inflammation / Q000473:pathology; D009336:Necrosis / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains; D012867:Skin; D013997:Time Factors
D000447:Aldehydes; D002021:Buffers; D005976:Glutaral