[An analysis of calcium pidolate absorption and a comparison with that of a salt in common use, gluconate-lactate-carbonate, in postmenopausal osteoporosis].
The absorption of calcium pidolate is studied in 10 females suffering from osteoporosis by oral overload compared to the results of the glucono-lactate-carbonate. 405 mq of Ca pidolate produced a higher excretion of calcium by urine and an increase of Ca levels in blood than that produced by 1000 mq of Ca glucono-lactate-carbonate. The tolerance and the lack of side effects were the common feature in both salts. There were no effects on parathyroid glands nor bone resorption. We concluded that calcium pidolate is a safe and efficient treatment for osteoporosis because of easy absorption, which is very helpful in maintaining the calcium balance.
Farrerons
J
J
Olazabal
A
A
Díaz López
C
C
López Ciudad
A
A
Rams
A
A
D000042:Absorption; D000368:Aged; D002118:Calcium / Q000493:pharmacokinetics* / Q000627:therapeutic use; D002119:Calcium Carbonate / Q000493:pharmacokinetics* / Q000627:therapeutic use; D002125:Calcium Gluconate / Q000493:pharmacokinetics* / Q000627:therapeutic use; D004338:Drug Combinations; D004341:Drug Evaluation; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D007773:Lactates / Q000493:pharmacokinetics* / Q000627:therapeutic use; D019344:Lactic Acid; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000188:drug therapy / Q000378:metabolism*; D011761:Pyrrolidonecarboxylic Acid / Q000493:pharmacokinetics* / Q000627:therapeutic use
D004338:Drug Combinations; D007773:Lactates; D019344:Lactic Acid; D002119:Calcium Carbonate; D002125:Calcium Gluconate; D002118:Calcium; D011761:Pyrrolidonecarboxylic Acid
Análisis de la absorción del pidolato de calcio y comparación con la da una sal de uso común, el glucono-lactato-carbonato, en la osteoporosis postmenopáusica.