Testing and abuse liability of drugs in humans.
In summary, there are a number of factors to be considered in abuse liability testing such as the purpose of the testing and its potential applications that determine which subject population we should employ. Furthermore, we should not expect to see a perfect correlation between abuse liability testing and the actual abuse of these drugs because there are many factors that will modulate or modify whether or not abuse liability becomes activated and the abuse of any specific drug becomes a social problem.
Schuster
C R
CR
National Institute on Drug Abuse, Rockville, Maryland 20857.
D000662:Amphetamines; D001569:Benzodiazepines; D004341:Drug Evaluation; D006801:Humans; D013287:Illicit Drugs; D019966:Substance-Related Disorders / Q000517:prevention & control
D000662:Amphetamines; D013287:Illicit Drugs; D001569:Benzodiazepines