Ultrastructure of the parathyroid gland of the mouse fetus after calcium chloride or ethylenediaminetetraacetic acid administration.
Ultrastructural changes of the parathyroid glands of 18-day-old mouse fetuses after administration of calcium chloride (calcium) or ethylenediaminetetraacetic acid (EDTA) were examined. Many chief cells in the parathyroid glans of the calcium-treated mouse fetuses contained poorly developed Golgi complexes and cisternae of the granular endoplasmic reticulum and many secretory granules as compared with those of the control fetuses. Many chief cells in the glands of the EDTA-treated mouse fetuses contained well-developed Golgi complexes and cisternae of the granular endoplasmic reticulum and many prosecretory granules as compared with those of the control fetuses. These findings suggest that calcium or EDTA affects the secretory activity of the parathyroid gland of the mouse fetus.
Ishizaki
N
N
Department of Anatomy, Gifu University School of Medicine, Japan.
Shoumura
S
S
Emura
S
S
Yamahira
T
T
Ito
M
M
Chen
H
H
Kanbara
K
K
Arakawa
M
M
Isono
H
H
D000818:Animals; D002122:Calcium Chloride / Q000008:administration & dosage*; D004492:Edetic Acid / Q000008:administration & dosage*; D005314:Embryonic and Fetal Development / Q000187:drug effects*; D051379:Mice; D008854:Microscopy, Electron; D010280:Parathyroid Glands / Q000187:drug effects / Q000196:embryology* / Q000648:ultrastructure
D004492:Edetic Acid; D002122:Calcium Chloride