title: [Gonadotropic insufficiency in men with disorders of spermatogenesis].
abstract: The results of the investigation of 111 male patients with azoospermia, oligozoospermia and asthenoteratozoospermia revealed gonadotropic insufficiency in 28 (25.2%). The mean level of LH in the peripheral blood of the patients (4.36 +/- 0.70 IU/l) did not differ significantly from the indices in the control group (5.71 +/- 0.64 IU/l). The blood FSH level (0.86 +/- 0.13 IU/l) was significantly lower than the control one (4.48 +/- 0.44 IU/l), p less than 0.001. The level of testosterone in 14 patients was within normal. The clinical signs of hypogonadism were slightly expressed, gynecomastia and anosmia were absent. In 6 of 11 patients the response of FSH to LH-RH i. v. injection was either absent or sharply decreased. The LH response was absent in 2 patients. A conclusion has been made that disorder of spermatogenesis can be the only noticeable manifestation of isolated insufficiency of FSH secretion by the pituitary gland.
authors.forename: V V
authors.initials: VV
authors.lastname: Potin
authors.forename: T I
authors.initials: TI
authors.lastname: Ustinkina
mesh_terms: D005640:Follicle Stimulating Hormone / Q000097:blood; D006062:Gonadotropins / Q000172:deficiency*; D006801:Humans; D007006:Hypogonadism / Q000097:blood; D007248:Infertility, Male / Q000503:physiopathology*; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D009845:Oligospermia / Q000503:physiopathology; D013091:Spermatogenesis; D013739:Testosterone / Q000097:blood
chemical_list: D006062:Gonadotropins; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
vernacular_title: Gonadotropnaia nedostatochnost' u muzhchin s narusheniiami spermatogeneza.