Immunohistochemical studies on the development of 5-HT (serotonin) neurons in the nuclei of the reticular formations of human fetuses.
5-HT-positive neurons were detected by the PAP immunohistochemical methods in different nuclei of the reticular formations of human fetuses as early as 10 weeks of gestation. The majority of positive 5-HT cells were located in dorsal raphe and central superior nuclei, and there was a reduction of these neurons per 40-microns section as the fetus aged.
Shen
W Z
WZ
Department of Anatomy, Jinan University, Guangzhou, China.
Luo
Z B
ZB
Zheng
D R
DR
Yew
D T
DT
D002452:Cell Count; D002454:Cell Differentiation / Q000502:physiology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007124:Immunoenzyme Techniques; D007231:Infant, Newborn; D009474:Neurons / Q000166:cytology; D011247:Pregnancy; D011903:Raphe Nuclei / Q000166:cytology; D012154:Reticular Formation / Q000166:cytology*; D012701:Serotonin / Q000096:biosynthesis*
D012701:Serotonin