title: [Factors causing deafness in deaf-mute students].
abstract: An analysis of 240 deaf-mute students revealed that the main cause of congenital deafness had been heredity (68.5%) which was different from that before 1970s. Of the patients with delayed deafness, 29.8% were hereditary. Altogether, 92 cases (38.3%) had hereditary deafness, among which, 50 cases (46 families) were of autosomal recessive and 42 cases (37 families) autosomal dominant. Thirty-eight cases (41.3%) had their deafness induced by ototoxic antibiotics. A significant familial history of high susceptibility to such antibiotics was available in 26 cases (68.4%). It is suggested that the key of deaf-prevention should be eugenics and the avoidance of ototoxic antibiotic abuse.
authors.forename: J
authors.initials: J
authors.lastname: Zhuang
mesh_terms: D002675:Child, Preschool; D003638:Deafness / Q000139:chemically induced / Q000235:genetics*; D005260:Female; D005839:Gentamicins / Q000009:adverse effects; D006801:Humans; D007223:Infant; D007612:Kanamycin / Q000009:adverse effects; D008297:Male; D013307:Streptomycin / Q000009:adverse effects
chemical_list: D005839:Gentamicins; D007612:Kanamycin; D013307:Streptomycin