title: The chronic proliferative disease of large granular lymphocytes.
abstract: This review deals with the chronic lymphoproliferative disease of large granular lymphocytes endowed with T and natural killer cell characteristics. The disease is sufficiently characterized to allow its distinction from other lymphoproliferative disorders of the T cell type. The heterogeneous clinical course and laboratory findings illustrate the complexity of the interaction between proliferating large granular lymphocytes and other haematopoietic cells.
authors.forename: R
authors.initials: R
authors.lastname: Bassan
authors.forename: A
authors.initials: A
authors.lastname: Rambaldi
authors.forename: T
authors.initials: T
authors.lastname: Barbui
mesh_terms: D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis; D001172:Arthritis, Rheumatoid / Q000150:complications; D001327:Autoimmune Diseases / Q000209:etiology; D001402:B-Lymphocytes / Q000473:pathology; D003937:Diagnosis, Differential; D008232:Lymphoproliferative Disorders / Q000175:diagnosis / Q000235:genetics / Q000276:immunology / Q000473:pathology; D010198:Pancytopenia / Q000209:etiology; D013601:T-Lymphocytes / Q000145:classification / Q000473:pathology*
chemical_list: D000945:Antigens, Differentiation, T-Lymphocyte