Lubrication of selected salivary molecules and artificial salivas.
The lubrication regime displayed by human salivas (parotid and submandibular-sublingual), purified salivary molecules (the mucins MG1 and MG2 and alpha-amylases), and selected artificial salivas (Oracare D, Saliva Substitute, and Orthana) was assessed in vitro using a friction-testing device. Thin-film (boundary) lubrication was observed for all of the salivary samples and two of the artificial salivas examined. Oracare D, a glycerol-based artificial saliva, was the exception since it lubricated by a thick-film (hydrodynamic) regime. On a molar basis, the best lubricants of the purified salivary molecules were MG1 greater than MG2 approximately nonglycosylated alpha-amylases approximately glycosylated alpha-amylases.
Aguirre
A
A
Mendoza
B
B
Reddy
M S
MS
Scannapieco
F A
FA
Levine
M J
MJ
Hatton
M N
MN
D000681:Amylases / Q000502:physiology*; D006801:Humans; D009067:Mouthwashes; D009077:Mucins / Q000502:physiology*; D012463:Saliva / Q000502:physiology*; D012464:Saliva, Artificial; D014783:Viscosity
D009067:Mouthwashes; D009077:Mucins; D012464:Saliva, Artificial; D000681:Amylases