Ascorbic acid, HDL cholesterol, and apolipoprotein A-I in an elderly Chinese population in Boston.
The relationships between plasma HDL cholesterol, apolipoprotein A-I, and plasma ascorbic acid were examined in 146 women and 92 men in a Chinese population in Boston, aged 60 and above. A significant partial correlation (r = 0.21, p = 0.015) between plasma ascorbic acid and plasma HDL cholesterol was observed among (predominantly nonsmoking) females after the effects of potentially confounding variables were taken into account. A similar relationship among 26 nonsmoking men was suggestive but inconclusive; there was no evidence of a relationship among 66 male smokers. The partial correlation between plasma apolipoprotein A-I and plasma ascorbic acid was marginally significant for women (r = 0.22, p = 0.057, n = 87) but was highly significant for men (r = 0.43, p = 0.007, n = 51). The correlation coefficient for men was highly dependent on smoking status, being 0.80 for those who never smoked and almost zero for current smokers.
Dallal
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GE
USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111.
Choi
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E
Jacques
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Schaefer
E J
EJ
Jacob
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RA
D000368:Aged; D000369:Aged, 80 and over; D016632:Apolipoprotein A-I; D001054:Apolipoproteins A / Q000097:blood*; D001205:Ascorbic Acid / Q000097:blood*; D044466:Asian People; D001900:Boston; D008076:Cholesterol, HDL / Q000097:blood*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012907:Smoking / Q000009:adverse effects
D016632:Apolipoprotein A-I; D001054:Apolipoproteins A; D008076:Cholesterol, HDL; D001205:Ascorbic Acid