[The diagnostic importance of determining minimal amounts of the Bence-Jones protein in the urine of patients with morphologically nondemonstrable lymphatic tumors].
Urinalysis by the IITP method in 115 patients with lymphatic tumors has shown that in half of them, BJ protein can be identified. The authors' and reported data evidence the lack of BJ proteinuria in normal people and in patients afflicted with other diseases. Since BJ proteinuria was demonstrable with the minimal tumorous mass in successfully treated patients with CLL and LC, the IITP method was used for excluding a morphologically undemonstrable lymphatic tumor in 23 patients with rheumatic diseases, AIHA, and splenomegaly of obscure genesis. Based on the identified BJ protein secretion in the urine, the diagnoses of CLL (I), LC (2), and LS (I) were proved in 4 cases. Later on these diagnoses were supported by the cytologic and histologic findings.
Sinitsina
T V
TV
Andreeva
N E
NE
D000328:Adult; D001536:Bence Jones Protein / Q000652:urine*; D003378:Counterimmunoelectrophoresis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007147:Immunoglobulin Light Chains / Q000032:analysis; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000175:diagnosis / Q000652:urine*; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000652:urine*; D008297:Male; D008875:Middle Aged; D012216:Rheumatic Diseases / Q000175:diagnosis / Q000652:urine; D013163:Splenomegaly / Q000175:diagnosis / Q000652:urine
D007147:Immunoglobulin Light Chains; D001536:Bence Jones Protein
Diagnosticheskoe znachenie opredeleniia minimal'nykh kolichestv belka Bens-Dzhonsa v moche bol'nykh s morfologicheski nedokazuemymi limfaticheskimi opukholiami.