[Clinical picture and course of newly detected pulmonary tuberculosis in elderly and senile patients, discharging L-forms of Mycobacterium tuberculosis].
One hundred and forty two new cases of pulmonary tuberculosis of elderly and senile ages were observed clinically. In terms of the vegetating mycobacterial population, all the patients were divided into 3 groups. It was shown that pronounced clinical and x-ray signs of pulmonary tuberculosis were characteristic of the patients isolating only bacterial forms of the pathogen (group 1). Intensive chemotherapy of the patients of that group was the most efficient. At the same time lethality in that group was the highest. In the patients isolating both the bacterial forms and the L-forms of the pathogen (group 2), the clinical signs of the disease were similar to those in the patients of group 1. However, the time-course of their clinical, x-ray and laboratory indices was slower and the therapy results were less satisfactory than in the patients isolating pure cultures of tubercle bacilli. In the patients isolating only L-transformed variants of tubercle bacilli (group 3), the clinical symptoms were characterized by their latent onset and torpid course. The treatment results in the patients of that group were not sufficient.
Kochetkova
E Ia
EIa
D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007740:L Forms / Q000302:isolation & purification*; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy
Klinika i techenie vpervye vyiavlennogo tuberkuleza legkikh u bol'nykh pozhilogo i starcheskogo vozrasta, vydeliaiushchikh L-formy Mikobakteriĭ tuberkuleza.