title: [Long-term results following surgery or radioiodine treatment of solitary autonomous adenoma of the thyroid gland].
abstract: 128 patients were investigated after surgery (n = 72) or 131-iodine therapy (n = 56) of a scintigraphically solitary, hyperfunctioning adenoma of the thyroid gland. The median follow-up period amounted to 10.6 years. Recurrent hyperthyroidism was observed in six patients after surgery and in one patient after 131-iodine therapy. Hypothyroidism occurred in one patient after 131-iodine therapy. The percentage of 131-iodine treated patients with a normal TSH-response to TSH-releasing hormone (TRH) increased during the follow-up period from 57 to 90%, whereas after surgery the percentage of patients showing a normal TSH-response to TSH decreased from 58 to 31%. This latter observation points to persistent hyperfunctioning tissue areas inducing late recurrent hyperthyroidism in 8.3% of the patients who underwent surgery.
authors.affiliation: Abteilung für Nuklearmedizin, Universitätskrankenhaus Hamburg-Eppendorf.
authors.forename: H W
authors.initials: HW
authors.lastname: Müller-Gärtner
authors.forename: C
authors.initials: C
authors.lastname: Schneider
authors.forename: B
authors.initials: B
authors.lastname: Riechert
authors.forename: D
authors.initials: D
authors.lastname: Kayser
authors.forename: B
authors.initials: B
authors.lastname: Kremer
mesh_terms: D000236:Adenoma / Q000532:radiotherapy / Q000601:surgery*; D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006980:Hyperthyroidism / Q000532:radiotherapy / Q000601:surgery*; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000097:blood; D011183:Postoperative Complications / Q000097:blood; D013964:Thyroid Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D013965:Thyroidectomy; D013972:Thyrotropin / Q000097:blood; D013973:Thyrotropin-Releasing Hormone
chemical_list: D007457:Iodine Radioisotopes; D013973:Thyrotropin-Releasing Hormone; D013972:Thyrotropin
vernacular_title: Langzeitergebnisse nach Operation oder Radiojodbehandlung des solitären autonomen Adenoms der Schilddrüse.