Changes of immunological parameters in immunocompromised patients under selective decontamination of the digestive tract. Third Part: Behaviour of some plasma proteins.
We studied the importance of changes in plasma protein concentrations in patients with hematologic systemic diseases treated by selective decontamination of the digestive tract. The concentrations of albumin, acute-phase proteins, immunoglobulins and fibronectin were determined by laser nephelometry in 125 serum samples of eight patients. Results obtained allow the following conclusions: 1. There was a correlation between the clinical condition and concentrations of acid alpha-1-glycoprotein, IgG, CRP and fibronectin. These concentrations might be important for assessment of the course of the disease, effectiveness of therapy and the detection of pathogenetic relations. 2. The acid alpha-1-glycoprotein is of particular importance since relations exist between changes in its concentration and therapeutic results as well as the prognosis of the disease.
Wulf
E
E
Institute of Immunology, Military Medical Academy, Bad Saarow, GDR.
Koch
H
H
Gille
R
R
D000209:Acute-Phase Proteins / Q000378:metabolism; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001798:Blood Proteins / Q000378:metabolism; D004064:Digestive System / Q000187:drug effects / Q000382:microbiology; D006402:Hematologic Diseases / Q000097:blood / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D007108:Immune Tolerance / Q000187:drug effects* / Q000276:immunology; D017053:Infection Control
D000209:Acute-Phase Proteins; D000890:Anti-Infective Agents; D001798:Blood Proteins