An on-line, column-switching high-performance liquid chromatographic procedure for the removal of probenecid from human plasma, serum, or urine in the quantitative determination of cefmetazole or cefoxitin.
Bothwell
W M
WM
Biofluids Analytical Laboratories, Drug Metabolism Research, Upjohn Company, Kalamazoo, MI 49001.
Cathcart
K S
KS
Bombardt
P A
PA
D001331:Automation; D002138:Calibration; D015311:Cefmetazole / Q000032:analysis* / Q000097:blood / Q000652:urine; D002440:Cefoxitin / Q000032:analysis* / Q000097:blood / Q000652:urine; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006801:Humans; D011339:Probenecid / Q000097:blood / Q000302:isolation & purification* / Q000652:urine; D015203:Reproducibility of Results
D015311:Cefmetazole; D002440:Cefoxitin; D011339:Probenecid