Lack of effects of a lyposterolic extract of Serenoa repens on plasma levels of testosterone, follicle-stimulating hormone, and luteinizing hormone.
Twenty men, aged 50 to 75 years (mean, 67 years), suffering from benign prostatic hypertrophy received 160 mg of a lyposterolic extract of Serenoa repens, twice daily for 30 days. Before and at the end of treatment, plasma levels of testosterone, follicle-stimulating hormone, and luteinizing hormone were determined. No changes in plasma hormone levels occurred as a result of treatment. It is concluded that Serenoa extract, which is useful in the treatment of benign prostatic hypertrophy, does not act via systemic changes of hormone levels.
Casarosa
C
C
Division of Urology, Hospital Riuniti S. Chiara, Pisa, Italy.
Cosci di Coscio
M
M
Fratta
M
M
D000368:Aged; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use*; D010946:Plants, Medicinal; D011470:Prostatic Hyperplasia / Q000097:blood / Q000188:drug therapy*; D028024:Serenoa; D013739:Testosterone / Q000097:blood*
D010936:Plant Extracts; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; C040972:saw palmetto extract