title: Distress call reactivation in isolated chicks: a behavioral indicator with high selectivity for antidepressants.
abstract: Four-day-old chicks respond to isolation with distress calling. A decrease in distress calling during isolation seems to reflect some general aspect of depressive syndrome and appears to be sensitive to pharmacological manipulation. Diverse clinically active antidepressants are able to counteract this decrease with high selectivity; non-antidepressants have either no influence or further inhibit the distress calling.
authors.affiliation: Department of Pharmacology, Boehringer Ingelheim, Federal Republic of Germany.
authors.forename: E
authors.initials: E
authors.lastname: Lehr
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001522:Behavior, Animal / Q000187:drug effects*; D002645:Chickens; D008297:Male; D012934:Social Isolation; D014828:Vocalization, Animal / Q000187:drug effects*
chemical_list: D000928:Antidepressive Agents