Rapidly progressive non-A, non-B hepatitis in patients with human immunodeficiency virus infection.
No information is available on the role of non-A, non-B hepatitis in the various hepatic abnormalities described in patients with the acquired immune deficiency syndrome. Of 97 patients referred with suspected non-A, non-B hepatitis, 3 were found to have antibody to the human immunodeficiency virus. These latter 3 patients all developed symptomatic cirrhosis within 3 yr of onset of hepatitis. Such a rapid progression of liver disease was rare in patients with non-A, non-B hepatitis who did not have simultaneous human immunodeficiency infection. These findings suggest that human immunodeficiency virus infection may potentiate the liver injury of chronic non-A, non-B hepatitis.
Martin
P
P
Liver Diseases Section, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.
Di Bisceglie
A M
AM
Kassianides
C
C
Lisker-Melman
M
M
Hoofnagle
J H
JH
D006679:HIV Seropositivity / Q000150:complications*; D006526:Hepatitis C / Q000150:complications* / Q000635:transmission; D006525:Hepatitis, Viral, Human; D006801:Humans; D008297:Male; D008875:Middle Aged