Characterization of an IgG2, G2m(23) anti-Rh-D antibody.
IgG2, G2m(23) anti-Rh-D antibodies were detected in the serum of a donor. It has been characterized by Gm typing and the use of polyclonal and mouse monoclonal anti-IgG subclasses (which had proved to be satisfactory for agglutination of sensitized red blood cells). This anti-D constitutes a good reagent for G2m(23) typing.
Dugoujon
J M
JM
Centre de Recherches du CNRS sur le Polymorphisme Génétique des Populations Humaines, Toulouse, France.
de Lange
G G
GG
Blancher
A
A
Alie-Daram
S
S
Marty
Y
Y
D000911:Antibodies, Monoclonal; D001782:Blood Donors; D003298:Coombs Test; D006386:Hemagglutination Tests; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D007129:Immunoglobulin Gm Allotypes / Q000276:immunology*; D007518:Isoantibodies / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D012204:Rh-Hr Blood-Group System / Q000276:immunology*
D000911:Antibodies, Monoclonal; D007074:Immunoglobulin G; D007129:Immunoglobulin Gm Allotypes; D007518:Isoantibodies; C033242:RH-antibodies; D012204:Rh-Hr Blood-Group System