title: Neuropeptide Y-immunoreactive cells in the caudal medulla project to the median preoptic nucleus.
abstract: The region surrounding the anteroventral third ventricle, particularly the median preoptic nucleus, has been implicated in the control of fluid balance and blood pressure. Previous studies indicate that catecholaminergic inputs from the caudal medulla are important in these controls. In this study we report that neuropeptide Y-immunoreactive cells in the caudal medulla project to the median preoptic nucleus in the basal forebrain. Notably these cells are found in the caudal ventral lateral medulla and the nucleus of the solitary tract. Since catecholaminergic projections to the median preoptic nucleus also arise from these regions the possibility of interactions between NPY and catecholamines exists, particularly in the control of fluid balance and blood pressure.
authors.affiliation: Department of Psychology, University of Iowa, Iowa City 52242.
authors.forename: G L
authors.initials: GL
authors.lastname: Edwards
authors.forename: J T
authors.initials: JT
authors.lastname: Cunningham
authors.forename: T G
authors.initials: TG
authors.lastname: Beltz
authors.forename: A K
authors.initials: AK
authors.lastname: Johnson
mesh_terms: D000818:Animals; D016650:Fluorescein-5-isothiocyanate; D005452:Fluoresceins; D005455:Fluorescent Antibody Technique; D007150:Immunohistochemistry; D008297:Male; D008526:Medulla Oblongata / Q000166:cytology* / Q000378:metabolism; D009478:Neuropeptide Y / Q000276:immunology / Q000378:metabolism*; D011301:Preoptic Area / Q000166:cytology* / Q000378:metabolism; D011817:Rabbits / Q000276:immunology; D051381:Rats; D011919:Rats, Inbred Strains; D013194:Staining and Labeling; D013861:Thiocyanates
chemical_list: D005452:Fluoresceins; D009478:Neuropeptide Y; D013861:Thiocyanates; D016650:Fluorescein-5-isothiocyanate