title: Enhanced inhibition of plant virus replication by pyridylthiourea compounds complexed with metal ions.
abstract: Inhibition of potato virus X replication can be enhanced by complexation of N-allyl-N'-2-pyridyl-thiourea and of N-phenyl-N'-2-pyridyl-thiourea with Cu+, Zn2+ and Cd2+. The antiphytoviral activity of some complexes with pyridylthiourea can be further augmented by adding small quantities of 2,4-dioxohexahydro-1,3,5-triazine.
authors.affiliation: Department of Life Sciences, Karl-Marx-University, Leipzig, G.D.R.
authors.forename: G
authors.initials: G
authors.lastname: Schuster
authors.forename: K A
authors.initials: KA
authors.lastname: Davarsky
authors.forename: G N
authors.initials: GN
authors.lastname: Vassilev
mesh_terms: D000998:Antiviral Agents / Q000494:pharmacology*; D002104:Cadmium / Q000494:pharmacology; D003300:Copper / Q000494:pharmacology; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000494:pharmacology*; D010942:Plant Viruses / Q000187:drug effects* / Q000502:physiology; D010947:Plants, Toxic; D011725:Pyridines / Q000494:pharmacology*; D013890:Thiourea / Q000031:analogs & derivatives* / Q000494:pharmacology; D014026:Nicotiana; D014227:Triazines / Q000494:pharmacology; D014779:Virus Replication / Q000187:drug effects; D015032:Zinc / Q000494:pharmacology
chemical_list: D000998:Antiviral Agents; D009942:Organometallic Compounds; D011725:Pyridines; D014227:Triazines; D002104:Cadmium; C020894:dioxohexahydrotriazine; D003300:Copper; D013890:Thiourea; D015032:Zinc