title: Clinical and radiographic improvement of bone of the second lumbar vertebra in Paget's disease following therapy with etidronate disodium: a case report.
abstract: Paget's disease of bone is most commonly seen in the spine; it may either be asymptomatic or may cause pain and neurologic impairment. We describe a patient with back pain due to Paget's disease of the second lumbar vertebra and spinal stenosis. The patient had a dramatic clinical and radiographic response to 2 courses of etidronate disodium, which was evidenced by resolution of the back pain and improvement in bony spinal stenosis. Etidronate may be effective in reversing bony spinal stenosis due to Paget's disease.
authors.affiliation: University of Pittsburgh School of Medicine, Pennsylvania.
authors.forename: J J
authors.initials: JJ
authors.lastname: Nicholas
authors.forename: D J
authors.initials: DJ
authors.lastname: Helfrich
authors.forename: L
authors.initials: L
authors.lastname: Cooperstein
authors.forename: M
authors.initials: M
authors.lastname: Goodman
mesh_terms: D012968:Etidronic Acid / Q000627:therapeutic use*; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D010001:Osteitis Deformans / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011859:Radiography; D013997:Time Factors
chemical_list: D012968:Etidronic Acid