[The interferon system in ducks infected with viral hepatitis B].
The duck peripheral blood lymphocytes and spleen cells were shown to be relatively resistant to interferon induction by viral (NDV) and nonviral (dsRNA) inducers as well as to Con A induction of gamma-interferon. The concentration of the inducers had to be increased 4-5-fold to induce interferon production. Charry valley ducks produced more alpha-interferon than Peking ducks. The level of interferon production induced by NDV and dsRNA (Ridostin) was similar in DHBV-positive Peking ducks and in the control group, but in the infected Charry valley ducks interferon production was lower than in the controls (224 to 180 U/0.1 ml in NDV-induced and from 192 to 43.3 U/0.1 ml in dsRNA-induced). Early bursectomy brought down the interferon production in non-infected ducts, but in DHBV-positive bursectomized ducks (Y) the level of interferon was higher than in the control bursectomized ducks.
Nosik
N N
NN
Li-sheng
Q
Q
Di
Q
Q
Yu-mei
W
W
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology; D004279:DNA, Viral / Q000032:analysis; D004372:Ducks / Q000276:immunology*; D006515:Hepatitis B virus / Q000302:isolation & purification*; D006524:Hepatitis, Viral, Animal / Q000276:immunology* / Q000382:microbiology; D007369:Interferon Inducers / Q000494:pharmacology; D007371:Interferon-gamma / Q000096:biosynthesis / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology; D009693:Nucleic Acid Hybridization; D011201:Poultry Diseases / Q000276:immunology
D004279:DNA, Viral; D007369:Interferon Inducers; D007371:Interferon-gamma
Sistema interferon u utok pri virusnom gepatite B.