A family exhibiting the cis-AB genotype.
Studies on blood samples from a 30-year-old woman of Korean origin, her husband and children, showed the presence of the cis-AB genotype in the mother and one child. The cis-AB red cells showed abnormal reactions with both polyclonal and monoclonal anti-B reagents and an elevated level of H antigen. The serum contained weak anti-B that reacted with normal B antigen but not with that on cis-AB cells. Normal levels of A substance but reduced levels of B and H substances were present in the saliva. Conversely, the serum showed reduced A and normal B and H blood group transferase activity.
Ford
D S
DS
National Blood Group Reference Laboratory, Commonwealth Serum Laboratories, Parkville, Victoria.
Condon
J A
JA
Bacon
J
J
Richards
V L
VL
Kronenberg
H
H
D000017:ABO Blood-Group System / Q000235:genetics*; D000328:Adult; D005260:Female; D005647:Fucosyltransferases / Q000097:blood; D005700:Galactosyltransferases / Q000097:blood; D005838:Genotype; D006801:Humans; D008297:Male; D017350:N-Acetylgalactosaminyltransferases; D010375:Pedigree; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000201:enzymology; D011296:Prenatal Diagnosis; D000097631:Galactoside 2-alpha-L-fucosyltransferase
D000017:ABO Blood-Group System; D005647:Fucosyltransferases; D005700:Galactosyltransferases; D017350:N-Acetylgalactosaminyltransferases; D000097631:Galactoside 2-alpha-L-fucosyltransferase; C003742:UDPgalactosamine-galactose acetylgalactosaminyltransferase