DNA binding of the mouse class II major histocompatibility CCAAT factor depends on two components.
A CCAAT-binding factor that recognizes a CCAAT sequence (Y box) located upstream of the major histocompatibility class II gene I-A beta has been partially purified. This CCAAT-binding factor was found to consist of two components, designated factors A and B, both of which were required for efficient binding to the DNA. Factor A had an apparent molecular size of 34 kilodaltons, and factor B had an apparent molecular size of 42 to 46 kilodaltons.
Celada
A
A
La Jolla Cancer Research Foundation, California 92037.
Maki
R A
RA
D000818:Animals; D001483:Base Sequence; D022762:CCAAT-Enhancer-Binding Proteins; D002845:Chromatography / Q000379:methods; D004247:DNA / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000302:isolation & purification / Q000378:metabolism*; D004591:Electrophoresis, Polyacrylamide Gel; D005802:Genes, MHC Class II; D051379:Mice; D008970:Molecular Weight; D013463:Sulfuric Acid Esters; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
D022762:CCAAT-Enhancer-Binding Proteins; D004268:DNA-Binding Proteins; D013463:Sulfuric Acid Esters; D014157:Transcription Factors; D004247:DNA; C007482:dimethyl sulfate