title: The mutagenicity of refuse leachate from a municipal incinerator.
abstract: The mutagenicity of refuse leachate from a municipal incinerator was studied by liquid rec-assay and Ames assay. Volatile components were found to be negative, and nonvolatile components positive, in the Ames assay and the leachate was found to have DNA-damaging capacity in the liquid rec-assay with S-9 mix. PAHs derived from tobacco ash and carbonyl compounds generated by the putrefaction of foods were confirmed to be main contributors to DNA-damaging capacity and mutagenicity in refuse leachate.
authors.affiliation: Department of Environmental Hygiene, Gifu Pharmaceutical University, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Kamiya
authors.forename: Y
authors.initials: Y
authors.lastname: Ose
authors.forename: Y
authors.initials: Y
authors.lastname: Sakagami
mesh_terms: D000818:Animals; D001412:Bacillus subtilis / Q000187:drug effects; D001711:Biotransformation; D004249:DNA Damage; D006801:Humans; D007564:Japan; D008862:Microsomes, Liver / Q000378:metabolism; D009152:Mutagenicity Tests; D009153:Mutagens / Q000032:analysis* / Q000494:pharmacology; D009154:Mutation; D012037:Refuse Disposal; D013014:SOS Response, Genetics; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics; D014505:Urban Population; D014873:Water Pollutants / Q000032:analysis
chemical_list: D009153:Mutagens; D014873:Water Pollutants