A report on 341 six-antigen matched transplants.
1. One-year graft survival for patients receiving 6-antigen matched transplants was 90% compared to 78% for control nonshipped, nonmatched kidneys. 2. Graft survival with more than 30 hours of cold ischemia time was 90% for 6-antigen matched transplants compared to 80% for control transplants with short cold ischemia times of less than 30 hours. 3. Among 188 paired kidneys in which 1 kidney was shipped and transplanted into a 6-antigen matched patient, the 1-year graft survival was 87% compared to 75% for the contralateral, nonshipped kidney. 4. Almost 40% of 6-antigen matched transplants were performed in sensitized patients. As many as 13% of the 6-antigen matched kidneys were grafted into highly sensitized patients. The 1-year graft survival of 32 patients with antibodies reactive to more than 80% of the random panel was 92% compared to 72% for transplants in similarly sensitized controls.
Takemoto
S
S
Terasaki
P I
PI
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D006085:Graft Survival; D006680:HLA Antigens; D006650:Histocompatibility Testing; D006801:Humans; D016030:Kidney Transplantation / Q000276:immunology* / Q000706:statistics & numerical data; D008875:Middle Aged; D009926:Organ Preservation; D011446:Prospective Studies; D012042:Registries; D012086:Reoperation
D006680:HLA Antigens