[Use of lithium carbonate as a leukocyte stimulant in acute radiation sickness in humans].
A total of 50 patients, who had suffered from acute radiation sickness (I-III degree of severity) as a result of the accident at the Chernobyl Nuclear Power Plant, were followed up for hematological changes. The absorbed dose of relatively even gamma-irradiation assessed by karyometry fluctuated from 0.5 to 5.7 Gy. In 17 of the patients the influence of lithium carbonate on the course of radiation neutropenia was evaluated. No appreciable effect of the agent administration in a dose of 900 mg/patient/day was recorder from 9 to 42 day after irradiation. The authors have also considered the correlations of the values of irradiation doses calculated by varying methods of biological dosimetry.
Konchalovskiĭ
M V
MV
Shishkova
T V
TV
Chotiĭ
V G
VG
Baranov
A E
AE
D000059:Accidents; D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000380:Agranulocytosis / Q000188:drug therapy*; D005260:Female; D006410:Hematopoiesis / Q000187:drug effects* / Q000528:radiation effects; D006801:Humans; D007958:Leukocyte Count / Q000187:drug effects / Q000528:radiation effects; D008094:Lithium / Q000627:therapeutic use*; D016651:Lithium Carbonate; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000188:drug therapy* / Q000209:etiology; D009504:Neutrophils / Q000187:drug effects* / Q000528:radiation effects; D009688:Nuclear Reactors; D011210:Power Plants; D011832:Radiation Injuries / Q000097:blood*; D013268:Stimulation, Chemical; D014455:Ukraine
D016651:Lithium Carbonate; D008094:Lithium
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