title: Profile analysis of chondroitin sulfates in human urine and serum.
abstract: A highly sensitive high-performance liquid chromatographic method with fluorometric postcolumn labeling using 2-cyanoacetamide was developed for the profile analysis of chondroitin sulfates (ChS) in normal human urine and serum. Over-sulfated disaccharide units such as di- or trisulfated unsaturated disaccharides in urine were estimated and unsaturated 6-sulfated disaccharide (delta Di-6S) was found as a major component from ChS in urine, although only small amounts of delta Di-6S from ChS were present in serum.
authors.forename: H
authors.initials: H
authors.lastname: Toyoda
authors.forename: S
authors.initials: S
authors.lastname: Yamanashi
authors.forename: Y
authors.initials: Y
authors.lastname: Hakamada
authors.forename: K
authors.initials: K
authors.lastname: Shinomiya
authors.forename: T
authors.initials: T
authors.lastname: Imanari
mesh_terms: D002807:Chondroitin / Q000031:analogs & derivatives*; D002809:Chondroitin Sulfates / Q000032:analysis* / Q000097:blood / Q000652:urine; D002851:Chromatography, High Pressure Liquid; D006801:Humans
chemical_list: D002807:Chondroitin; D002809:Chondroitin Sulfates