title: [The destruction of perikaryas of the mesencephalic reticular formation and the posterior hypothalamus does not cause major disorders of awakening in the cat].
abstract: Ibotenic acid microinjections have been realized at the level of the mesencephalic reticular formation and the posterior hypothalamus in 7 cats. This technique has led to a quasi-total destruction of cell bodies in the two areas (including the histaminergic neurons). 2 to 3 days after such lesions, there were no major effects on behavioral waking. These results do not favor the hypothesis of the existence of a waking system at the level of the mesencephalic reticular formation and/or posterior hypothalamus.
authors.affiliation: Département de Médecine expérimentale, I.N.S.E.R.M., Lyon.
authors.forename: M
authors.initials: M
authors.lastname: Denoyer
authors.forename: C
authors.initials: C
authors.lastname: Buda
authors.forename: M
authors.initials: M
authors.lastname: Jouvet
mesh_terms: D000818:Animals; D002415:Cats; D005260:Female; D007031:Hypothalamus / Q000502:physiology*; D007034:Hypothalamus, Posterior / Q000187:drug effects / Q000502:physiology*; D007051:Ibotenic Acid / Q000494:pharmacology; D008297:Male; D008636:Mesencephalon / Q000187:drug effects / Q000502:physiology*; D012894:Sleep Stages / Q000187:drug effects / Q000502:physiology*; D014851:Wakefulness
chemical_list: D007051:Ibotenic Acid
vernacular_title: La destruction des périkaryas de la formation réticulée mésencéphalique et de l'hypothalamus postérieur n'entraîne pas de troubles majeurs de l'éveil chez le chat.