C-fos mRNA expression following electrical-induced seizure and acute nociceptive stress in mouse brain.
A single electroconvulsive shock (ECS) induced a rapid and transient expression of c-fos mRNA in mouse brain. In earclipped sham controls, low but significant expression of c-fos mRNA was also observed. These data suggest that c-fos mRNA may be transiently induced by seizure activity as well as much more subtle and qualitative different stimuli, such as the acute nociceptive stress associated with earclipping.
Nakajima
T
T
Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892.
Daval
J L
JL
Gleiter
C H
CH
Deckert
J
J
Post
R M
RM
Marangos
P J
PJ
D000818:Animals; D004558:Electric Stimulation; D008297:Male; D051379:Mice; D010146:Pain / Q000378:metabolism*; D011518:Proto-Oncogene Proteins / Q000378:metabolism*; D016760:Proto-Oncogene Proteins c-fos; D012333:RNA, Messenger / Q000378:metabolism*; D012640:Seizures / Q000378:metabolism* / Q000503:physiopathology; D013997:Time Factors
D011518:Proto-Oncogene Proteins; D016760:Proto-Oncogene Proteins c-fos; D012333:RNA, Messenger