[An immunologic method for identification of M. tuberculosis and M. bovis (BCG) based on the use of monoclonal antibodies].
Monoclonal antibodies interacting with specific selectivity with human tubercle bacilli (monoclonal antibodies of the cell producing strain 62D) and bovine tubercle bacilli (BCG) (monoclonal antibodies of the cell producing strain 60D) were produced with hybridoma technology. A rapid, productive and safe procedure for identification of M. tuberculosis and M. bovis (BCG) was developed on the basis of solid phase enzyme immunoassay. The immunological procedure was compared with the biochemical (niacin) method for identification of mycobacteria. The immunological procedure was shown to be reliable and promising for practical use.
Androsova
M V
MV
Vladimirskiĭ
M A
MA
Alekseeva
G I
GI
D000818:Animals; D000911:Antibodies, Monoclonal; D006168:Guinea Pigs; D006801:Humans; D006825:Hybridomas; D007124:Immunoenzyme Techniques; D009163:Mycobacterium bovis / Q000302:isolation & purification*; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D009525:Niacin
D000911:Antibodies, Monoclonal; D009525:Niacin
Immunologicheskiĭ metod identifikatsii M. tuberculosis i M. bovis (BTsZH) na osnove primeneniia monoklonal'nykh antitel.