title: [Determination of variability factors of arterial pressure using 3843 self-measurements of blood pressure in 34 active hypertensives].
abstract: To assess the role of physical activity, stress and treatment on BP variations in working hypertensives we used repeated self measurements of BP which are cheaper and more simple than ambulatory BP measurements but allow for a smaller number of measurements. 34 working hypertensives self measured daily life BP, at home and at workplace, 7 times a day, for at least one week, before and 6 weeks after beta-blockade with metoprolol 200 to 400 mg daily. They used a Spengler SP9 electronic sphygmometer and specified on 4 grades scales their physical activity and stress just before measurement. The time for self measurement of BP was settled according to occupations more than to clocktime. The equipment was standardized at each visit by measuring BP with a mercury manometer then with the electronic sphygmometer. There were no significant differences neither for SBP nor for DBP and the two measures correlate closely (r = 0.91), P = 0.0001). Analysis of variance on SBP exhibits the role of time (p (0.001) and stress (p (0.0001). Physical activity does not interfere (p = 0.19). There is no difference between work days and sundays (p = 0.17). Treatment effect was very strong (p (0.0001) but there was no interaction neither with physical activity nor stress. Analysis of variance on DBP exhibits similar results except that BP on workdays is significantly higher than on sundays (p = 0.03). We conclude that: Repeated self measurement of BP is able to display variation of BP with occupations and stress. Beta-blockade lowers BP but does not interfere with variability.
authors.affiliation: Service de cardiologie, hôpital militaire du Val de Grâce, Paris.
authors.forename: A
authors.initials: A
authors.lastname: Chatelin
authors.forename: R
authors.initials: R
authors.lastname: Brion
authors.forename: D
authors.initials: D
authors.lastname: Moyse
authors.forename: J
authors.initials: J
authors.lastname: Droniou
authors.forename: M
authors.initials: M
authors.lastname: Le Davay
authors.forename: J P
authors.initials: JP
authors.lastname: Ollivier
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D001795:Blood Pressure Determination / Q000379:methods; D005260:Female; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D005082:Physical Exertion; D012648:Self Care; D013315:Stress, Psychological / Q000503:physiopathology; D014937:Work
vernacular_title: Approche des facteurs de variabilité de la pression artérielle par 3 843 automesures tensionnelles chez 34 hypertendus actifs.