Molecular epidemiology of Pseudomonas aeruginosa--urinary tract infections in paraplegic patients.
84 Pseudomonas aeruginosa strains from 29 paraplegic patients with urinary tract infections (UTI) and from the water reservoirs of specialized wards in two German hospitals were typed using a P. aeruginosa-specific DNA probe. P. aeruginosa strains were present in 51% of all accessible water reservoirs, including sinks of wash-basins and toilets in the wards. 14 of the 29 patients with UTI (48%) were infected by P. aeruginosa strains which were also isolated from these sources. Groups of up to four patients were infected by single strains. Some of the strains persisted in the wards and were isolated from the water reservoirs five to eight months after causing UTI. 89.5% of the investigated water samples yielded P. aeruginosa strains which were identical with strains from up to nine other sites. The wide distribution of single P. aeruginosa genotypes in the ward, the isolation of strains causing UTI from rooms inaccessible to the patients, and the outbreak of UTI caused by single, identical P. aeruginosa strains in groups of patients within short time periods, suggest that the strains are distributed by the personnel rather than by the patients who for the most part are immobile.
Worlitzsch
D
D
Department of General and Environmental Hygiene, Hygiene Institut, Universität Tübingen, Federal Republic of Germany.
Wolz
C
C
Botzenhart
K
K
Hansis
M
M
Burgdörfer
H
H
Ogle
J W
JW
Döring
G
G
D003428:Cross Infection / Q000453:epidemiology / Q000209:etiology* / Q000382:microbiology; D004196:Disease Outbreaks; D005838:Genotype; D006801:Humans; D010264:Paraplegia / Q000150:complications*; D011552:Pseudomonas Infections / Q000453:epidemiology / Q000209:etiology* / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000145:classification / Q000235:genetics; D014552:Urinary Tract Infections / Q000453:epidemiology / Q000209:etiology* / Q000382:microbiology; D014871:Water Microbiology