Nursing care of patients receiving orthoclone OKT 3.
Orthoclone OKT 3 (muromonab-CD3) is a monoclonal antibody to the T3 antigen of human T cells that has been used successfully to treat acute cell-mediated renal allograft rejection. The adverse reactions of OKT 3, though temporary, are quite disabling to patients. Common nursing diagnoses include potential alteration in respiratory function; altered body temperature: hyperthermia; alteration in comfort: pain; potential fluid volume deficit; potential for infection; and knowledge deficit. Patients receiving OKT 3 require diligent nursing care and monitoring during the course of therapy.
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D000911:Antibodies, Monoclonal / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D006084:Graft Rejection / Q000187:drug effects; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods / Q000451:nursing*; D016853:Muromonab-CD3; D009730:Nursing Assessment; D009733:Nursing Diagnosis
D000911:Antibodies, Monoclonal; D016853:Muromonab-CD3