Effect of dihydrotestosterone on testicular and accessory gland function in male rhesus monkeys.
Pituitary, testicular and accessory gland functions were assessed at intervals of 10-20 days in adult male rhesus monkeys given 10, 100 or 1000 micrograms dihydrotestosterone (DHT). Circulating levels of LH and testosterone were suppressed. Ejaculated spermatozoa showed morphological abnormalities and decrease in motility but sperm counts were unaffected. Seminal fructose was decreased in animals receiving DHT. Sexual behaviour was maintained in these animals.
Ramakrishnan
P R
PR
Department of Reproductive Biology, All India Institute of Medical Sciences, New Delhi.
Kaur
J
J
Rajalakshmi
M
M
D000135:Acid Phosphatase / Q000378:metabolism; D000818:Animals; D013196:Dihydrotestosterone / Q000494:pharmacology*; D004958:Estradiol / Q000097:blood; D005640:Follicle Stimulating Hormone / Q000097:blood; D005632:Fructose / Q000032:analysis; D005997:Glycerylphosphorylcholine / Q000032:analysis; D007986:Luteinizing Hormone / Q000032:analysis; D008253:Macaca mulatta; D008297:Male; D011388:Prolactin / Q000097:blood; D012661:Semen / Q000032:analysis / Q000187:drug effects*; D013076:Sperm Count / Q000187:drug effects; D013081:Sperm Motility / Q000187:drug effects; D013094:Spermatozoa / Q000166:cytology / Q000187:drug effects*; D013737:Testis / Q000187:drug effects* / Q000502:physiology; D013739:Testosterone / Q000097:blood
D013196:Dihydrotestosterone; D005632:Fructose; D013739:Testosterone; D004958:Estradiol; D005997:Glycerylphosphorylcholine; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D000135:Acid Phosphatase