Placental and decidual u-PA, t-PA, PAI-1 and PAI-2 concentrations, as affected by cervical dilatation with laminaria tents or Hegar dilators.
The effect of cervical dilatation on PA and PAI concentrations was compared in a laminaria tent group and a mechanical dilatation (control) group. In both groups, u-PA and t-PA were found to be present both in decidual and placental tissue. Values for PAI-1 in the decidua were higher in the laminaria tent group than in controls, and those for PAI-2 in the placenta were lower. These findings provide support for the contention that cervical dilatation with laminaria tents may result in partial detachment of the placenta.
Jonasson
A
A
Department of Obstetrics, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden.
Larsson
B
B
Lecander
I
I
Astedt
B
B
D003656:Decidua / Q000378:metabolism; D004107:Dilatation and Curettage; D005260:Female; D005343:Fibrinolytic Agents / Q000378:metabolism*; D006801:Humans; D007795:Laminaria; D010920:Placenta / Q000378:metabolism; D010960:Plasminogen Activators / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D015849:Plasminogen Inactivators; D011247:Pregnancy; D010959:Tissue Plasminogen Activator / Q000378:metabolism*; D014568:Urokinase-Type Plasminogen Activator / Q000378:metabolism*
D005343:Fibrinolytic Agents; D015849:Plasminogen Inactivators; D010960:Plasminogen Activators; D010959:Tissue Plasminogen Activator; D014568:Urokinase-Type Plasminogen Activator