title: Attaching and effacing Escherichia coli infections in calves, pigs, lambs, and dogs.
abstract: Attaching and effacing Escherichia coli (AEEC) adhere to mucosal epithelium in both small and large intestine and induce a distinctive lesion characterized by an irregular scalloped appearance of the epithelial layer. Infection with attaching and effacing E. coli was detected in 14 calves, 7 pigs, 2 lambs, and 3 dogs. Affected animals were from farms and kennels in South Dakota, Minnesota, Iowa, Nebraska, and Wisconsin. Ages of affected animals were calves, 2 days to 4 months; pigs, 1-6 weeks; lambs, 1 week; and dogs, 7-8 weeks. Clinical signs included diarrhea in all animals, but other nonenteric disease problems were present in some animals. Concurrent infection with other enteropathogens was detected in 9 calves and 5 pigs. Infection with AEEC appeared to be the sole cause of illness and death in some animals. There was evidence of intestinal hemorrhage in 5 of the calves and in all 3 dogs. Attaching and effacing lesions varied from small scattered foci to widespread involvement of large areas of intestinal mucosa. Verotoxin was produced by E. coli strains isolated from 9 calves, but not by strains from pigs, lambs, or dogs.
authors.affiliation: Department of Veterinary Science, South Dakota State University, Brookings 57007.
authors.forename: B H
authors.initials: BH
authors.lastname: Janke
authors.forename: D H
authors.initials: DH
authors.lastname: Francis
authors.forename: J E
authors.initials: JE
authors.lastname: Collins
authors.forename: M C
authors.initials: MC
authors.lastname: Libal
authors.forename: D H
authors.initials: DH
authors.lastname: Zeman
authors.forename: D D
authors.initials: DD
authors.lastname: Johnson
mesh_terms: D000818:Animals; D001422:Bacterial Adhesion; D001427:Bacterial Toxins / Q000096:biosynthesis; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology*; D004283:Dog Diseases / Q000382:microbiology*; D004285:Dogs; D004768:Enterotoxins / Q000096:biosynthesis; D004926:Escherichia coli / Q000378:metabolism; D004927:Escherichia coli Infections / Q000382:microbiology / Q000662:veterinary*; D007422:Intestines / Q000382:microbiology / Q000473:pathology; D012756:Sheep; D012757:Sheep Diseases / Q000382:microbiology*; D022622:Shiga Toxin 1; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology*
chemical_list: D001427:Bacterial Toxins; D004768:Enterotoxins; D022622:Shiga Toxin 1