[Post-transfusional hepatitis].
Viral hepatitis has become a major complication of transfusion. Its frequency depends upon the number of blood units injected (packed cells, platelets, fresh frozen plasma), the origin of blood donors and the quality of controls performed after blood donation. Several reports estimate that this transmitted disease affects 2.3 to 26.5% of recipients (average: 10%). Among 100 cases of post-transfusion hepatitis, 10 are due to the hepatitis B virus (despite systematic search for HBs Ag), 89 are due to one of the non-A non-B viruses (not detectable by specific serological tests) and 1 to several viruses, specially CMV. The systematic exclusion of prospective blood donors with a hig level of aminotransferase (above twice the normal value) and/or with an anti-HBc antibody prevents the transmission of all hepatitis B and of two-thirds of non-A non-B hepatitis. About 5% of all blood donors are thus excluded. This practice has been made legal in France in October, 1988.
Ducos
J
J
D006508:Hepatitis Antibodies / Q000032:analysis; D006509:Hepatitis B / Q000635:transmission; D006526:Hepatitis C / Q000201:enzymology / Q000276:immunology / Q000635:transmission; D006525:Hepatitis, Viral, Human / Q000635:transmission*; D006801:Humans; D000637:Transaminases / Q000097:blood; D065227:Transfusion Reaction
D006508:Hepatitis Antibodies; D000637:Transaminases
Les hépatites post-transfusionnelles.