A new CO2 inhalation system for studying regulation of breathing.
This paper describes the development of a computer-controlled system that controls inspired CO2 or end-tidal PCO2 (PETCO2) to follow preprogrammed functions such as step, sinusoid, and pulse, under normoxic, hyperoxic, and hypoxic conditions. The system uses a proportional-integral (PI) controller that was optimized by adjusting the PI parameters so as to minimize the integral-time of absolute error (ITAE) performance parameter.
Mussell
M J
MJ
Department of Information, Faculty of Engineering, Yamagata University, Yonezawa, Japan.
Nakazono
Y
Y
Miyamoto
Y
Y
D000703:Analog-Digital Conversion; D002245:Carbon Dioxide / Q000378:metabolism*; D004867:Equipment Design; D006801:Humans; D009330:Nebulizers and Vaporizers; D012119:Respiration / Q000502:physiology*
D002245:Carbon Dioxide