Clomiphene citrate and ovarian resistance.
An uncommon association between clomiphene citrate and the development of ovarian resistance to gonadotrophins is described. We advise against the use of clomiphene in the rare patient with the resistant ovary syndrome, and advise caution in any patient who exhibits a decreasing oestrogen response to clomiphene ovulation induction.
McKenna
K M
KM
Endocrine Clinic, Royal Women's Hospital, Carlton.
Evans
J H
JH
D000328:Adult; D002996:Clomiphene / Q000494:pharmacology*; D004351:Drug Resistance; D005260:Female; D005640:Follicle Stimulating Hormone / Q000494:pharmacology*; D006801:Humans; D010053:Ovary / Q000187:drug effects*; D010060:Ovulation / Q000187:drug effects*; D010062:Ovulation Induction
D002996:Clomiphene; D005640:Follicle Stimulating Hormone