[Diagnosis of rabies infection in animals using monoclonal antibodies].
Two monoclonal antibodies (M.A.), specific for viral nucleocapsid, the M.A. D-20 and the M.A. D-43 raised against a fixed strain of rabies virus (C.V.S. 11), have been tested in parallel with a standard antirabies serum (S.A.R.) in diagnosis of animal rabies virus infection. 44 brain imprints from animals which died from rabies were tested by indirect immunofluorescent technique with monoclonal antibodies. Constant correlation has been found between the M.A. D-43 and the S.A.R. in the diagnosis of animal rabies virus infection in all cases studied. For M.A. D-20, concordance of results with S.A.R. was found only in limited number of cases.
Akacem
O
O
Taril
A
A
Benelmouffok
A
A
Bemansour
A
A
Couillin
P
P
Brahimi
M
M
Benhassine
M
M
D000818:Animals; D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D001921:Brain / Q000276:immunology; D002213:Capsid / Q000276:immunology; D005455:Fluorescent Antibody Technique; D007106:Immune Sera; D011237:Predictive Value of Tests; D011818:Rabies / Q000175:diagnosis / Q000662:veterinary*; D011820:Rabies virus / Q000276:immunology*; D014758:Viral Core Proteins / Q000276:immunology
D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D007106:Immune Sera; D014758:Viral Core Proteins
Diagnostic de l'infection rabique chez l'animal par le biais des anticorps monoclonaux.