Permeability of different parts of the peritoneal mesothelium to solutes: an in vitro study.
The authors studied the in vitro permeability of different fragments of the rabbit's peritoneum to urea, inulin, horseradish peroxidase, and ferritin. Parietal peritoneum has a lower permeability to middle and large molecules than visceral peritoneum. In addition the local anesthetic, bupivacaine had a different effect on the mesothelial permeability of visceral peritoneum than on that of parietal peritoneum.
Breborowicz
A
A
Department of Pathophysiology, Medical Academy, Poznan, Poland.
Rodela
H
H
Knapowski
J
J
Oreopoulos
D G
DG
D000818:Animals; D002045:Bupivacaine / Q000494:pharmacology; D005293:Ferritins / Q000493:pharmacokinetics; D006735:Horseradish Peroxidase / Q000493:pharmacokinetics; D007444:Inulin / Q000493:pharmacokinetics; D010537:Peritoneum / Q000502:physiology*; D010539:Permeability / Q000187:drug effects; D011817:Rabbits; D014508:Urea / Q000493:pharmacokinetics
D014508:Urea; D007444:Inulin; D005293:Ferritins; D006735:Horseradish Peroxidase; D002045:Bupivacaine