Evaluation of restriction endonuclease analysis as an epidemiologic typing system for Branhamella catarrhalis.
Restriction endonuclease analysis (REA) was evaluated as an epidemiologic typing tool to distinguish Branhamella catarrhalis strains. Fourteen beta-lactamase-producing strains were collected over a 16-month period at a hospital where a nosocomial outbreak of this organism was previously documented by REA. REA produced 12 distinct patterns which correlated with epidemiologic data. Chromosomal REA appears to be a useful technique for distinguishing B. catarrhalis strains.
Patterson
J E
JE
Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06510.
Patterson
T F
TF
Farrel
P
P
Hierholzer
W J
WJ
Zervos
M J
MJ
D001424:Bacterial Infections / Q000453:epidemiology / Q000382:microbiology*; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D004269:DNA, Bacterial / Q000032:analysis*; D004196:Disease Outbreaks; D004587:Electrophoresis, Agar Gel; D006801:Humans; D001936:Moraxella catarrhalis / Q000145:classification* / Q000235:genetics; D000091402:Prohibitins; D015183:Restriction Mapping; D012189:Retrospective Studies
D004269:DNA, Bacterial; C000717331:PHB2 protein, human; D000091402:Prohibitins