title: [Echocardiography detection of reversible regional disorders of contraction in patients with unstable angina pectoris and Prinzmetal angina during an attack].
abstract: We studied seven patients with Prinzmetal's angina and three patients with unstable angina pectoris type III (according to the criteria of Conti) during and after a spontaneous attack of angina pectoris by two-dimensional echocardiography. All patients underwent coronary angiography. The echocardiographic studies were performed during the attack (phase I), immediately after the attack (phase II), and 24 h after the attack (control). Left ventricular ejection fraction was significantly decreased during the attack (38.1 +/- 11% vs 59.8 +/- 7%), while left ventricular end-diastolic volume was increased (71.9 +/- 28 ml/m2 vs 50.3 +/- 13 ml/m2). The double product of heart rate and systolic blood pressure was equal at the 3 different examination times. In all patients transient regional disturbances of left ventricular contraction could be observed. In six patients the wall motion disturbances had already disappeared at phase II, while in four patients hypokinetic regions could still be found. At control, nine patients showed a normal left ventricular contraction pattern, while one patient with previous anterior myocardial infarction showed a small region of anterior akinesia. In all patients coronary artery obstructions were found in the same region of the left ventricle, where transient wall motion abnormalities occurred. Thus, two-dimensional echocardiography performed during an attack of angina pectoris in patients with Prinzmetal's angina and unstable angina pectoris type III can evaluate the localization, as well as the extent of transient myocardial wall motion abnormalities.
authors.affiliation: Medizinische Klinik III, Universität Freiburg.
authors.forename: T
authors.initials: T
authors.lastname: Hofmann
authors.forename: W
authors.initials: W
authors.lastname: Kasper
authors.forename: A
authors.initials: A
authors.lastname: Geibel
authors.forename: H
authors.initials: H
authors.lastname: Wollschläger
authors.forename: T
authors.initials: T
authors.lastname: Meinertz
authors.forename: H
authors.initials: H
authors.lastname: Just
mesh_terms: D000787:Angina Pectoris / Q000503:physiopathology*; D000788:Angina Pectoris, Variant / Q000503:physiopathology*; D000789:Angina, Unstable / Q000503:physiopathology*; D006328:Cardiac Catheterization; D002302:Cardiac Output / Q000187:drug effects; D017023:Coronary Angiography; D004452:Echocardiography; D004562:Electrocardiography; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D009203:Myocardial Infarction / Q000503:physiopathology; D009543:Nifedipine / Q000008:administration & dosage; D005996:Nitroglycerin / Q000008:administration & dosage
chemical_list: D005996:Nitroglycerin; D009543:Nifedipine
vernacular_title: Echokardiographischer Nachweis reversibler regionaler Kontraktionsstörungen bei Patienten mit instabiler Angina pectoris und Prinzmetal-Angina im Anfall.