[Determination of lactate dehydrogenase isozymes in the cochleae of guinea pigs].
The isozymes of lactate dehydrogenase (LDH) in perilymph and homogenates from vascular stria, Corti's organ, and vestibular membrane of healthy guinea pigs were determined with the micro-homogenate electrophoresis technique. The results were compared with those in serum and cerebrospinal fluid. It was found that electrophoretogram of individual homogenate or perilymph, which showed the isozymes of LDH, had a special pattern different from that in the serum. The factors which might affect LDH in perilymph had been discussed.
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D000818:Animals; D003051:Cochlea / Q000201:enzymology*; D004591:Electrophoresis, Polyacrylamide Gel; D006168:Guinea Pigs; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000032:analysis* / Q000097:blood; D009925:Organ of Corti / Q000201:enzymology; D010498:Perilymph / Q000201:enzymology; D013316:Stria Vascularis / Q000201:enzymology
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase