title: Benign recurrent intrahepatic cholestasis in a Chinese girl.
abstract: A 15 year old Chinese girl presented with features of benign recurrent intrahepatic cholestasis, confirmed by liver biopsies performed during attack and remission. Her only younger brother also has features of this syndrome. Serial biochemistry monitoring during a recent attack demonstrated that a rise in the serum bile acids preceded the clinical onset of symptoms and the rise in serum bilirubin and ductal enzymes by 8 weeks. Whether this earlier rise in serum bile acids is related to the pathogenetic mechanism of this syndrome remains to be elucidated.
authors.affiliation: Department of Medicine, Queen Mary Hospital, University of Hong Kong.
authors.forename: J Y
authors.initials: JY
authors.lastname: Lau
authors.forename: A S
authors.initials: AS
authors.lastname: Lok
authors.forename: C L
authors.initials: CL
authors.lastname: Lai
authors.forename: P C
authors.initials: PC
authors.lastname: Wu
authors.forename: H J
authors.initials: HJ
authors.lastname: Lin
mesh_terms: D000293:Adolescent; D001647:Bile Acids and Salts / Q000097:blood; D002780:Cholestasis, Intrahepatic / Q000453:epidemiology* / Q000235:genetics; D005260:Female; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D008111:Liver Function Tests; D012008:Recurrence
chemical_list: D001647:Bile Acids and Salts