Acute erythroblastic leukemia. Cytological, cytogenetic and phenotypic studies in one case.
We report the clinical, cytological, immunophenotypic, and cytogenetic findings in one patient with acute erythroblastic leukemia. Blast cells were identified by their reactivity with the early erythroid antibodies FA6-152 and carbonic anhydrase I. The leukemic blasts had no specific differentiating features identifying them as erythroblasts even at an ultrastructural level. Cytogenetic studies revealed multiple chromosome aberrations: 45,XX,i(11q),-16,-17,-21,+der(21)t(21;?)(q22;?),+mar 1.
Soler
J
J
Servei d'Hematologia, Hospital de la Santa Creu i Sant Pau, Barcelona, España.
Pujol-Moix
N
N
Bosch
M A
MA
Guanyabens
C
C
Aventin
A
A
Boque
C
C
Brunet
S
S
D000368:Aged; D002869:Chromosome Aberrations; D004920:Erythropoiesis; D005260:Female; D006801:Humans; D004915:Leukemia, Erythroblastic, Acute / Q000235:genetics / Q000276:immunology / Q000473:pathology*; D008854:Microscopy, Electron; D010641:Phenotype