title: A new CO2 inhalation system for studying regulation of breathing.
abstract: This paper describes the development of a computer-controlled system that controls inspired CO2 or end-tidal PCO2 (PETCO2) to follow preprogrammed functions such as step, sinusoid, and pulse, under normoxic, hyperoxic, and hypoxic conditions. The system uses a proportional-integral (PI) controller that was optimized by adjusting the PI parameters so as to minimize the integral-time of absolute error (ITAE) performance parameter.
authors.affiliation: Department of Information, Faculty of Engineering, Yamagata University, Yonezawa, Japan.
authors.forename: M J
authors.initials: MJ
authors.lastname: Mussell
authors.forename: Y
authors.initials: Y
authors.lastname: Nakazono
authors.forename: Y
authors.initials: Y
authors.lastname: Miyamoto
mesh_terms: D000703:Analog-Digital Conversion; D002245:Carbon Dioxide / Q000378:metabolism*; D004867:Equipment Design; D006801:Humans; D009330:Nebulizers and Vaporizers; D012119:Respiration / Q000502:physiology*
chemical_list: D002245:Carbon Dioxide