title: [Study of the antimicrobial sensitivity, auxotype, serotype and plasmid analysis of 75 strains of Neisseria gonorrhoeae isolated in Barcelona].
abstract: The sensitivity of five antimicrobials (penicillin, cefoxitin, tetracycline, ceftazidime and spectinomycin) was assayed in 75 Neisseria gonorrhoeae strains, isolated from May 1986 to December 1987 in a general hospital in Barcelona. Auxotype, serotype and plasmid analysis studies were also performed on these strains. Twenty-six (34%) penicillinase-producing strains were found. 49% of the non-penicillinase-producing strains showed intermediate resistance to penicillin and 12% were resistant with MIC greater than 1 mg/1. 6% were resistant to tetracycline and cefoxitin, respectively, and all were sensitive to ceftazidime and spectinomycin. All the penicillinase-producing strains had the plasmid Africa and three of them had a diffuser plasmid of 24.5 mD. With regard to the auxotype study, most of the strains were prototrophic (38%) followed by the proline dependent ones (38%). 64% of the penicillinase-producing strains belonged to the serogroup W I, while 77% of the non-penicillinase-producing strains were in the W II/III serogroup.
authors.forename: T
authors.initials: T
authors.lastname: Baró
authors.forename: J
authors.initials: J
authors.lastname: García Conesa
authors.forename: J A
authors.initials: JA
authors.lastname: Vázquez
authors.forename: R
authors.initials: R
authors.lastname: Miralles
authors.forename: C
authors.initials: C
authors.lastname: Alia
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D005260:Female; D006069:Gonorrhea / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009344:Neisseria gonorrhoeae / Q000145:classification / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Estudio de la sensibilidad antimicrobiana, auxotipia, serotipia y análisis plasmídico de 75 cepas de Neisseria gonorrhoeae aisladas en Barcelona.