title: Cryptosporidiosis in children and adults: parasitological and clinico-epidemiological features.
abstract: By using the elective diagnosis methodology for Cryptosporidium (modified Ziehl-Neelsen and Heine stainings), 481 faeces samples from patients--children and adults--presenting acute or prolonged gastroenteritis and also from asymptomatic ones, but with professional, immunological or pharmacological risk for infection, were studied. Twelve Cryptosporidium positive cases were identified, meaning a general prevalence of 2.48% Cryptosporidium infection was detected in all investigated epidemiological groups: children, animal handlers, immunodeficient patients, immunocompetent adults with acute gastroenteritis. The risk factors hierarchy elicited the role of children collectivities attending, for acquiring the parasite in infantile cryptosporidiosis, while the opportunistic and zoonotic feature of the disease was especially present in adults' cryptosporidiosis. The assessment of cryptosporidiosis evolution, according to patients' immune status, has not allowed an obvious clinical discrepancy, since the immunocompetent subjects with professional risk had presented a prolonged oocysts excretion. The different clinico-epidemiological and parasitological features of Cryptosporidium infection are commented and the importance of applying Cryptosporidium methodology in current diagnosis practice is emphasized.
authors.forename: L
authors.initials: L
authors.lastname: Lazăr
authors.forename: S
authors.initials: S
authors.lastname: Rădulescu
mesh_terms: D000328:Adult; D000818:Animals; D002648:Child; D003457:Cryptosporidiosis / Q000453:epidemiology / Q000276:immunology / Q000469:parasitology*; D003458:Cryptosporidium / Q000302:isolation & purification; D005243:Feces / Q000469:parasitology; D006801:Humans; D007121:Immunocompetence / Q000276:immunology; D007153:Immunologic Deficiency Syndromes / Q000453:epidemiology / Q000276:immunology / Q000469:parasitology; D015995:Prevalence; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D013194:Staining and Labeling / Q000379:methods