title: Distribution of lipid in hepatic tissue of dairy goats in positive and negative energy balance.
abstract: Liver biopsies are commonly used to obtain tissue to determine hepatic lipid content in ruminants, particularly the dairy cow. The location of the biopsy is unknown and it is assumed that the sample is representative of the entire organ. This study investigated the distribution of lipid in the caudate, left, right, and quadrate lobes of goat livers having normal or elevated lipid content. Goats that experienced negative energy balance for 4 days had significantly greater hepatic total lipids, primarily due to a 4-fold increase in triglycerides, than goats in positive energy balance. Triglyceride concentrations were similar among lobes within energy balance groups. Within the positive energy balance treatment, the caudate lobe had a significantly greater total lipid concentration than the other lobes, which had a similar lipid concentration. Total lipid concentrations were similar among lobes obtained from goats in negative energy balance.
authors.forename: T C
authors.initials: TC
authors.lastname: Skaar
authors.forename: R R
authors.initials: RR
authors.lastname: Grummer
mesh_terms: D000818:Animals; D004032:Diet; D004734:Energy Metabolism; D006041:Goats / Q000378:metabolism*; D008055:Lipids / Q000032:analysis*; D008099:Liver / Q000032:analysis*; D014018:Tissue Distribution; D014280:Triglycerides / Q000032:analysis
chemical_list: D008055:Lipids; D014280:Triglycerides