Immunochemical and structural characterization of an IgG1 heavy chain disease.
The immunochemical and structural analysis of an IgG1 heavy chain disease is reported. The abnormal component is characterized by extensive deletion including the CH1 domain and most or all of the VH region.
Sala
P
P
Istituto di Chimica Clinica, Indiana University, Bloomington.
Tonutti
E
E
Pizzolitto
S
S
Noda
S
S
Putnam
F W
FW
De Lange
G
G
Boccazzi
C
C
Bottaro
A
A
Carbonara
A O
AO
D000368:Aged; D000369:Aged, 80 and over; D000595:Amino Acid Sequence; D004588:Electrophoresis, Cellulose Acetate; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006362:Heavy Chain Disease / Q000276:immunology*; D006801:Humans; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D007074:Immunoglobulin G / Q000276:immunology*; D007142:Immunoglobulin gamma-Chains; D008969:Molecular Sequence Data; D008970:Molecular Weight; D010641:Phenotype
D007074:Immunoglobulin G; D007142:Immunoglobulin gamma-Chains