Unusually high concentrations of Zn alpha 2-glycoprotein and the lack of alpha 2HS-glycoprotein in human ejaculates.
Ejaculates of 132 nonvasectomized and 129 vasectomized men were assayed for their Zn alpha 2- and alpha 2HS-glycoprotein contents by radial immunodiffusion. The respective mean concentrations of Zn alpha 2-glycoprotein were 319 and 309 mg/L, respectively, but these fluids were devoid of alpha 2HS-glycoprotein. In comparison, the concentration of these two proteins in serum of normal men were 62 and 617 mg/L for Zn alpha 2- and alpha 2HS-glycoprotein, respectively. Because albumin in the ejaculates is 100-fold less concentrated than in serum, the fivefold increase in the concentration of Zn alpha 2-glycoprotein of the ejaculates represents about a 500-fold enrichment of this protein in the ejaculates over the concentration expected by comparison with albumin.
Bürgi
W
W
Zentrallaboratorium, Kantonsspital, Aarau, Switzerland.
Simonen
S
S
Baudner
S
S
Schmid
K
K
D000328:Adult; D001798:Blood Proteins / Q000032:analysis*; D006023:Glycoproteins / Q000032:analysis* / Q000097:blood; D006801:Humans; D005779:Immunodiffusion / Q000379:methods; D008297:Male; D008875:Middle Aged; D012661:Semen / Q000032:analysis*; D029589:Seminal Plasma Proteins; D014659:Vasectomy; D000090203:Zn-Alpha-2-Glycoprotein; D060749:alpha-2-HS-Glycoprotein
C556354:AHSG protein, human; D001798:Blood Proteins; D006023:Glycoproteins; D029589:Seminal Plasma Proteins; D000090203:Zn-Alpha-2-Glycoprotein; D060749:alpha-2-HS-Glycoprotein