Single photon emission computed tomography with 99mTc HM-PAO in the study of focal epilepsy.
We used 99mTc HM-PAO SPECT to study 50 patients with partial epilepsy: 47 interictally and 3 during a seizure. All 3 patients studied during a seizure presented an area of increased tracer uptake. Of those in whom recordings were taken during seizure-free intervals 35 (74%) showed perfusion asymmetries: 27 (57%) with decreased and 8 (17%) with increased uptake. We discuss the findings and compare them with those of similar studies using SPECT and positron emission tomography.
Grasso
E
E
Divisione di Neurologia, Ospedale Civile S. Croce, Cuneo.
Ambrogio
L
L
Cognazzo
A
A
Gerbino-Promis
P C
PC
Zagnoni
P
P
Camuzzini
G F
GF
Papaleo
A
A
Acchiardi
F
F
Perno
G
G
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004828:Epilepsies, Partial / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D014055:Tomography, Emission-Computed
D009942:Organometallic Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime