title: [Synthesis of new nitrosoureas].
abstract: Two chemical pathways were used for the synthesis of three new N'-(2-chloroethyl)-N-[2-(4-alkoxyphenylthio)ethyl]-N'-nitrosoureas and two new N'-(2-chloroethyl)-N)[2-(4-alkoxyphenyl-thio)ethyl]-N-nitrosoureas . The study of the cytotoxicity of the three N'-nitrosoureas, was carried out in two experimental models (P 388 and NSCLCN6).
authors.forename: A
authors.initials: A
authors.lastname: Papadaki-Valiraki
authors.forename: T
authors.initials: T
authors.lastname: Siatra-Papastaikoudi
authors.forename: A L
authors.initials: AL
authors.lastname: Skaltsounis
authors.forename: C
authors.initials: C
authors.lastname: Roussakis
mesh_terms: D000818:Animals; D006801:Humans; D007945:Leukemia, Lymphoid / Q000188:drug therapy; D008175:Lung Neoplasms / Q000473:pathology; D051379:Mice; D009607:Nitrosourea Compounds / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D009607:Nitrosourea Compounds
vernacular_title: Synthèse de nouvelles nitrosourées.