[Preventive hepatic arterial infusion in high risk cases of liver metastasis from gastric cancer].
Preventive hepatic arterial infusion (MMC 20 mg, 5-FU 500 mg; one-shot) was applied to high risk cases of liver metastasis from gastric cancer. Postoperative liver metastases were found in 5 (16.1%) of 31 arterial infusion patients, against 9 (25.7%) of 35 controls. The average interval to recurrence from operation was 6.8 +/- 3.0 (SD) months in arterial infusion, against 5.4 +/- 3.0 months in controls. These results suggest that preventive hepatic arterial infusion will decrease the rate of postoperative liver metastasis from gastric cancer.
Takahashi
Y
Y
Dept. of Surgery, Kanazawa University.
Mai
M
M
Fujimoto
T
T
Ohta
T
T
Ueda
H
H
Ogino
T
T
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage* / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004341:Drug Evaluation; D005472:Fluorouracil / Q000008:administration & dosage; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial; D007430:Intraoperative Care; D008113:Liver Neoplasms / Q000517:prevention & control* / Q000556:secondary; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery; D013997:Time Factors
D008937:Mitomycins; D016685:Mitomycin; D005472:Fluorouracil