title: Non-von Recklinghausen's neurofibromatosis resembling a giant pigmented nevus.
abstract: We report the case of a 30-year-old female patient with non-von Recklinghausen's neurofibromatosis. In our opinion it does not fit within a system of classification recently described. Clinically, the abnormality resembled a giant pigmented nevus; however, light- and electron microscopy findings were consistent with those of a neurofibroma. No other symptoms of classic neurofibromatosis or other diseases were present. The family history showed no evidence of neurofibromatosis. To the best of our knowledge this manifestation of non-von Recklinghausen's neurofibromatosis has not been previously described. The cause and the inheritance pattern of this variant are not clear.
authors.affiliation: Department of Dermato-Venereology, Erasmus University, Rotterdam, The Netherlands.
authors.forename: M T
authors.initials: MT
authors.lastname: Bousema
authors.forename: V D
authors.initials: VD
authors.lastname: Vuzevski
authors.forename: A P
authors.initials: AP
authors.lastname: Oranje
authors.forename: F
authors.initials: F
authors.lastname: Heule
authors.forename: E
authors.initials: E
authors.lastname: Stolz
authors.forename: T
authors.initials: T
authors.lastname: van Joost
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D009456:Neurofibromatosis 1 / Q000145:classification / Q000473:pathology*; D009508:Nevus, Pigmented / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*