The effect of prolactin on calcium homeostasis in coho salmon (Oncorhynchus kisutch).
The response of plasma prolactin (PRL) to manipulations of plasma calcium were investigated in coho salmon. Injection of 3.16 mumol EGTA/10 g body weight (to reduce the plasma calcium activity) resulted in significantly higher plasma PRL levels. Lower doses of EGTA (1.06 and 2.13 mumol/10 g body wt) had no effect on plasma PRL concentrations. Injection of 8.75 mumol CaCl2/10 g body wt (but not 4.35 mumol CaCl2/10 g body wt) resulted in significantly lower plasma PRL levels. Plasma total calcium and sodium concentrations were significantly elevated following three daily injections of 0.5 micrograms/g pure chum salmon PRL. This is the first report of a role for salmon PRL in calcium homeostasis of Oncorhynchus.
Fargher
R C
RC
Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
McKeown
B A
BA
D000818:Animals; D002118:Calcium / Q000097:blood* / Q000378:metabolism; D002122:Calcium Chloride / Q000494:pharmacology; D004533:Egtazic Acid / Q000494:pharmacology; D006706:Homeostasis / Q000187:drug effects*; D011388:Prolactin / Q000097:blood / Q000494:pharmacology*; D012474:Salmon / Q000378:metabolism*; D012964:Sodium / Q000097:blood
D004533:Egtazic Acid; D011388:Prolactin; D012964:Sodium; D002122:Calcium Chloride; D002118:Calcium