title: The effect of disodium cromoglycate and ketotifen on the excretion of histamine and N tau-methylimidazole acetic acid in urine of patients with mastocytosis.
abstract: Treatment of four mastocytosis patients with the mast cell stabilising drugs, disodium cromoglycate and ketotifen failed to alter significantly the urinary excretion levels of histamine or N tau-methylimidazole acetic acid. No clinical improvement was noted in any subject after treatment by either drug.
authors.affiliation: Institute of Dermatology, St Thomas' Hospital, United Medical School, London.
authors.forename: A I
authors.initials: AI
authors.lastname: Mallet
authors.forename: P
authors.initials: P
authors.lastname: Norris
authors.forename: N B
authors.initials: NB
authors.lastname: Rendell
authors.forename: E
authors.initials: E
authors.lastname: Wong
authors.forename: M W
authors.initials: MW
authors.lastname: Greaves
mesh_terms: D000328:Adult; D004205:Cromolyn Sodium / Q000627:therapeutic use*; D005260:Female; D006632:Histamine / Q000652:urine*; D006801:Humans; D007093:Imidazoles / Q000652:urine*; D007665:Ketotifen / Q000627:therapeutic use*; D008297:Male; D008415:Mastocytosis / Q000188:drug therapy* / Q000652:urine; D008875:Middle Aged
chemical_list: D007093:Imidazoles; C002667:methylimidazoleacetic acid; D006632:Histamine; D004205:Cromolyn Sodium; D007665:Ketotifen