[Evaluation of different technics of uterine evacuation as a risk factor for invasive and metastatic trophoblastic neoplasms].
A study was conducted to determine the effect of the form of uterine evacuation (curettage or vacuum aspiration) and of the use of oxytocin on the incidence of invasive/metastatic gestational trophoblastic neoplasia among patients with a diagnosis of molar abortion. The study was conducted on 42 patients with a histopathological diagnosis of benign complete hydatidiform mole and with a uterine height of more than 12cm. Twenty-five patients were submitted to uterine evacuation by curettage and 17 to uterine evacuation by vacuum aspiration. Twenty-seven of the same 42 patients received oxytocin to promote dilation of the cervix and/or partial mole expulsion, and 15 were not treated with this drug. Statistical analysis showed that the use of oxytocin before uterine evacuation was a factor contributing to a higher risk of development of invasive neoplasia, especially when associated with curettage of the uterus.
de Andrade
J M
JM
Bighetti
S
S
Kim
T Y
TY
de Freitas
M M
MM
D004107:Dilatation and Curettage / Q000009:adverse effects* / Q000379:methods; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000209:etiology*; D009362:Neoplasm Metastasis / Q000175:diagnosis; D009366:Neoplasm Seeding; D010121:Oxytocin / Q000009:adverse effects*; D011247:Pregnancy; D012189:Retrospective Studies; D012307:Risk Factors; D014594:Uterine Neoplasms / Q000209:etiology*; D014619:Vacuum Curettage / Q000009:adverse effects* / Q000379:methods
D010121:Oxytocin
Avaliação de diferentes técnicas de esvaziamento uterino como fator de risco para neoplasia trofoblástica invasora e metastática.