Lithium carbonate for aggression in mentally retarded persons.
These are the results of a retrospective study in which we reviewed the charts of 38 consecutive aggressive mentally retarded persons who were treated with lithium carbonate. All subjects were residents of a university operated program that serves mentally retarded persons with behavioral disorders. Over 63% of these subjects evidenced a greater than 30% reduction in the frequency of aggressiveness subsequent to the start of lithium therapy. Subjects with higher serum lithium levels had a more favorable response to lithium, along with those exhibiting higher levels of hyperactivity and violence before treatment.
Spreat
S
S
Temple University Woodhaven Center, Philadelphia, PA 19154.
Behar
D
D
Reneski
B
B
Miazzo
P
P
D000328:Adult; D000374:Aggression / Q000187:drug effects*; D001521:Behavior Therapy; D003131:Combined Modality Therapy; D005260:Female; D006778:Hospitals, Psychiatric; D006801:Humans; D008607:Intellectual Disability / Q000188:drug therapy* / Q000523:psychology; D008094:Lithium / Q000627:therapeutic use*; D016651:Lithium Carbonate; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012917:Social Adjustment
D016651:Lithium Carbonate; D008094:Lithium