title: Mechanism of fibroplasia in chronic active hepatitis. An immunohistochemical study of various collagen types, fibronectin and laminin in human liver.
abstract: The cytoplasm of human bile ductule epithelia was found to be Type V collagen positive, demonstrating that the epithelia were able to generate this type of collagen. The ductules proliferated greatly with Type V collagen positive cytoplasm in piece-meal necrosis of chronic active hepatitis (CAH). The capillary-like bile ductules inside human hepatic lobules were identified. Our findings might explain the mechanism of fibroplasia in CAH.
authors.forename: Y R
authors.initials: YR
authors.lastname: Liang
mesh_terms: D003094:Collagen / Q000032:analysis / Q000145:classification; D005353:Fibronectins / Q000032:analysis; D006509:Hepatitis B / Q000150:complications; D006521:Hepatitis, Chronic / Q000150:complications / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D007797:Laminin / Q000032:analysis; D008103:Liver Cirrhosis / Q000209:etiology / Q000473:pathology*; D011347:Procollagen / Q000032:analysis; D012189:Retrospective Studies
chemical_list: D005353:Fibronectins; D007797:Laminin; D011347:Procollagen; D003094:Collagen