[Clinical and experimental studies on the effect of xue mai tong on coronary heart disease].
This article deals with the treatment of hypercoagulability with CHD by the mechanism of resolving phlegm and alleviating stagnation on the basis of the viewpoints that "body fluid and blood are derived from the same source" and that "Phlegm and blood are of the same stasis". The study on 74 patients who received Xue Mai Tong and 31 controls who were treated by promoting blood circulation to remove stasis showed an overall effective rate of 85.13% (63 cases) and a evident effective rate of 59.46% (44 cases) for angina pectoris in the treatment group. The efficacy of the treatment group with Xue Mai Tong was proved to be better than that of the controls (P less than 0.05). Animal experiments demonstrated that Xue Mai Tong improved microcirculation perfusion as compared with the controls (P less than 0.05) as evaluated by the length and wet weight of the thrombus.
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D000368:Aged; D000787:Angina Pectoris / Q000097:blood / Q000188:drug therapy*; D000818:Animals; D000941:Antigens / Q000032:analysis; D001809:Blood Viscosity / Q000187:drug effects*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005169:Factor VIII / Q000032:analysis / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D008833:Microcirculation / Q000187:drug effects; D008875:Middle Aged; D009262:Nails / Q000098:blood supply; D011817:Rabbits; D014841:von Willebrand Factor
D000941:Antigens; D004365:Drugs, Chinese Herbal; D014841:von Willebrand Factor; D005169:Factor VIII