title: Common bile-duct mucosa in choledochoduodenostomy patients--histological and histochemical study.
abstract: We describe the histological and histochemical changes of the common bile-duct mucosa in specimens obtained by means of peroral cholangioscopy, 1-12 years after choledochoduodenal anastomosis. Our findings--hyperplasia of the superficial epithelium, metaplastic goblet cells containing predominantly acid sialomucins, and pyloric-like gland formation containing neutral mucins--express a morphological and functional differentiation of the common bile-duct mucosa that probably facilitates its survival in a different environment. We consider that these adaptive changes may explain the uneventful long-term postoperative period of choledochoduodenostomized patients.
authors.affiliation: Department of Surgery, University of Thessaloniki, Greece.
authors.forename: E
authors.initials: E
authors.lastname: Eleftheriadis
authors.forename: V
authors.initials: V
authors.lastname: Tzioufa
authors.forename: K
authors.initials: K
authors.lastname: Kotzampassi
authors.forename: H
authors.initials: H
authors.lastname: Aletras
mesh_terms: D002768:Choledochostomy; D003135:Common Bile Duct / Q000737:chemistry / Q000473:pathology*; D004848:Epithelium / Q000473:pathology; D006801:Humans; D009077:Mucins / Q000737:chemistry; D009092:Mucous Membrane / Q000737:chemistry / Q000473:pathology; D052116:Sialomucins; D013194:Staining and Labeling
chemical_list: D009077:Mucins; D052116:Sialomucins