Campylobacter pylori in upper digestive tract diseases in children.
Results of studies on the frequency of the occurrence of the bacteria, Campylobacter pylori, in the mucous membrane of the gastric antrum are presented in this paper. The study was carried out on 61 children treated for chronic abdominal pain. The diagnosis was established on the basis of flexible endoscopy and histology of antral biopsies. The presence of Campylobacter pylori was determined using the CLO-test. The positive CLO-test was obtained in 87.5% of children with gastritis, in 75% of children with duodenal ulcer and in only 17% of children from control group (p less than 0.001). Four-week therapy with De Nol eradicated Campylobacter pylori in 60% of treated children, and reduced infection in the next 25%. These bacteria seem to play an important role in the pathogenesis of chronic gastritis and peptic ulcer disease.
Celińska-Cedro
D
D
Socha
J
J
Teisseyre
M
M
D000293:Adolescent; D000863:Antacids / Q000627:therapeutic use; D001729:Bismuth / Q000627:therapeutic use; D002169:Campylobacter Infections / Q000188:drug therapy; D002648:Child; D002908:Chronic Disease; D005260:Female; D005756:Gastritis / Q000382:microbiology*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D009942:Organometallic Compounds / Q000627:therapeutic use; D010437:Peptic Ulcer / Q000382:microbiology*
D000863:Antacids; D009942:Organometallic Compounds; C002791:bismuth tripotassium dicitrate; D001729:Bismuth