"Lysostrip" experiments with HLA class II antigens. II. Incomplete interdependence of surface mobility of supertypic DR and narrow DR specificities.
Utilizing the lysostrip technique we analyzed the relations between the mobility of supertypic HLA-DRw52 and DRw53, and narrow DR specificities. Different types of determinants were found, the one removed only by supertypic anti-DR allosera, the second removed by narrow anti-DR allosera, and the third removed by supertypic anti-DR and narrow anti-DR allosera as well. The results are discussed in terms of intermolecular complexes formed on cell surface by HLA class II antigens.
Kałamarz
M
M
Department of Clinical Immunology, Polish Academy of Sciences, Wrocław.
Matej
H
H
D001402:B-Lymphocytes / Q000276:immunology*; D002462:Cell Membrane / Q000276:immunology; D000939:Epitopes / Q000378:metabolism; D006684:HLA-DR Antigens / Q000378:metabolism*; D006801:Humans; D007152:Immunologic Capping; D066298:In Vitro Techniques; D007518:Isoantibodies
D000939:Epitopes; D006684:HLA-DR Antigens; D007518:Isoantibodies