Variations and comparisons in medium-depth chemical peeling.
Two effective methods in chemical peeling, solid carbon dioxide plus trichloroacetic acid and Jessner's solution plus trichloroacetic acid, were compared clinically with photographs and histologically with serial biopsies. Carbon dioxide produced a deeper wound than Jessner's solution, and CO2 + TCA was slightly deeper than Jessner's + TCA but was probably not significantly deeper from a clinical standpoint except in correcting scarring. Triple consecutive applications of TCA can substantially increase wound depth with both combination peels.
Brody
H J
HJ
Emory University School of Medicine, Atlanta, Georgia.
D000287:Administration, Topical; D000328:Adult; D002245:Carbon Dioxide / Q000008:administration & dosage; D002615:Chemexfoliation / Q000379:methods*; D004338:Drug Combinations / Q000008:administration & dosage; D004817:Epidermis / Q000473:pathology; D000431:Ethanol / Q000008:administration & dosage; D005148:Facial Dermatoses / Q000473:pathology / Q000628:therapy; D005260:Female; D006801:Humans; D007773:Lactates / Q000008:administration & dosage; D019344:Lactic Acid; D009336:Necrosis; D010859:Pigmentation Disorders / Q000473:pathology / Q000628:therapy; D012118:Resorcinols / Q000008:administration & dosage; D012459:Salicylates / Q000008:administration & dosage; D014238:Trichloroacetic Acid / Q000008:administration & dosage; D014945:Wound Healing
D004338:Drug Combinations; C061170:Jessner's solution; D007773:Lactates; D012118:Resorcinols; D012459:Salicylates; D002245:Carbon Dioxide; D019344:Lactic Acid; D000431:Ethanol; D014238:Trichloroacetic Acid