Malignant hyperthermia in a patient with sickle cell anemia.
A sixteen-year-old male with sickle cell anemia and congenital strabismus developed malignant hyperthermia a few minutes after the administration of succinylcholine, used as the general anesthetic for corrective eye surgery. The patient's hemoglobin S level was reduced to fifteen percent before the operation. He recovered uneventfully within a few hours. Increased serum creatinine phosphokinase activity and pathological changes observed in the muscle biopsy along with strabismus suggest that the patient had an inherited susceptibility to malignant hyperthermia.
Gürgey
A
A
Altay
C
C
Ozgen
S
S
D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000150:complications*; D001706:Biopsy; D006801:Humans; D008297:Male; D008305:Malignant Hyperthermia / Q000150:complications* / Q000209:etiology / Q000473:pathology; D009132:Muscles / Q000473:pathology; D013390:Succinylcholine / Q000009:adverse effects*
D013390:Succinylcholine