[Rhesus immunization in a rhesus-positive pregnant woman: fetal erythroblastosis caused by the rhesus antibody anti-C].
A rhesus-D-positive woman aged 32 years with two previous pregnancies was delivered of an infant with erythroblastosis foetalis caused by the rhesus antibody anti-c produced by alloimmunization during pregnancy. Screening for antibodies in the 12th week of pregnancy yielded negative results. No screening was undertaken in the 35th week of pregnancy. The infant was born with severe anaemia. Following delivery, the anti-c alloimmunization was diagnosed and three exchange transfusions were administered. On the fourth day of life, the infant developed the inspissated bile syndrome. No cerebral disorders were demonstrated. Antibody screening of rhesus-positive women has now been introduced at the 35th week of pregnancy to avoid similar cases.
Konstantin-Hansen
K F
KF
Larsen
H L
HL
Hejl
M
M
D000328:Adult; D004899:Erythroblastosis, Fetal / Q000276:immunology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007518:Isoantibodies / Q000032:analysis*; D011247:Pregnancy; D012203:Rh Isoimmunization / Q000276:immunology*
D007518:Isoantibodies; C051138:anti-c antibody
Rhesusimmunisering hos rhesus-positiv gravid: erythroblastosis foetalis forårsaget af rhesusantistoffet anti-C.