title: Association of class I, II, and III MHC gene products with systemic lupus erythematosus. Results of a Central European multicenter study.
abstract: Class I, II, and III MHC gene products were examined in 248 Central European SLE patients. The previously reported association with HLA-A1, -B8 and -DR3, and C4AQ0 alleles was confirmed. The frequency of HLA-DR2 was also slightly elevated in SLE patients, while no increase in C4BQ0 alleles was observed. Additional findings were a significantly increased frequency of HLA-B13 and a significant decrease of HLA-B44.
authors.affiliation: Department of Medicine, Universities of Bern, Switzerland.
authors.forename: K
authors.initials: K
authors.lastname: Hartung
authors.forename: A
authors.initials: A
authors.lastname: Fontana
authors.forename: M
authors.initials: M
authors.lastname: Klar
authors.forename: H
authors.initials: H
authors.lastname: Krippner
authors.forename: K
authors.initials: K
authors.lastname: Jörgens
authors.forename: B
authors.initials: B
authors.lastname: Lang
authors.forename: H H
authors.initials: HH
authors.lastname: Peter
authors.forename: W J
authors.initials: WJ
authors.lastname: Pichler
authors.forename: D
authors.initials: D
authors.lastname: Schendel
authors.forename: M
authors.initials: M
authors.lastname: Robin-Winn
mesh_terms: D000483:Alleles; D005060:Europe; D005787:Gene Frequency; D005805:Genes, MHC Class I; D005802:Genes, MHC Class II; D006680:HLA Antigens / Q000032:analysis* / Q000235:genetics; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000235:genetics / Q000276:immunology*; D008285:Major Histocompatibility Complex; D015337:Multicenter Studies as Topic
chemical_list: D006680:HLA Antigens