title: Pentafluorobenzoic anhydride as a derivatizing agent for alcohols and hydroxy fatty acid methyl esters detected by electron capture in gas chromatography.
abstract: Pentafluorobenzoate derivatives of primary and secondary alcohols have been prepared using pentafluorobenzoic anhydride. The gas chromatographic properties of the homologous series of the methyl esters of 2-hydroxycarboxylic acids from C12 to C26 have been studied on the high-temperature stationary phase Poly-S 179. The suitability of determining trace amounts of these compounds using gas chromatography with an electron-capture detector and with electron-capture negative-ion chemical-ionization mass spectrometry is discussed.
authors.affiliation: Eye Research Institute of Retina Foundation, Boston, MA 02114.
authors.forename: D V
authors.initials: DV
authors.lastname: Crabtree
authors.forename: A J
authors.initials: AJ
authors.lastname: Adler
authors.forename: G J
authors.initials: GJ
authors.lastname: Handelman
mesh_terms: D000812:Anhydrides; D001565:Benzoates; D002264:Carboxylic Acids / Q000032:analysis*; D002849:Chromatography, Gas; D004952:Esters / Q000032:analysis*; D006880:Hydroxy Acids / Q000032:analysis*; D007202:Indicators and Reagents; D005464:Fluorobenzenes; D005466:Fluorocarbons
chemical_list: D000812:Anhydrides; D001565:Benzoates; D002264:Carboxylic Acids; D004952:Esters; D006880:Hydroxy Acids; D007202:Indicators and Reagents; C060431:pentafluorobenzoic anhydride; D005464:Fluorobenzenes; D005466:Fluorocarbons