Pubertal changes in the secretion of gonadotropic hormones, testicular gonadotropic receptors and testicular function in the ram.
Developmental changes in pituitary content and secretory patterns of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and prolactin (PRL), testicular size and steroidogenic function, testicular LH- and FSH-binding activity, and growth of the accessory sex organs were examined for 24 Dorset X Leicester X Suffolk rams (born in March) every 30 days from 30 to 150 days of age, and again at 200 days. Pituitary LH and FSH contents increased between 30 and 60 days of age and remained constant until 150 days, when contents were somewhat greater than on either 120 or 200 days. LH-pulse amplitude and frequency, and mean FSH concentration, were highest at 60 and (or) 90 days of age. Testicular growth increased dramatically between 90 and 150 days of age in association with increases in the number of LH- (100-fold) and FSH- (33-fold) binding sites in the testis and a small increase in blood testosterone concentration (1 ng/ml). During the same period, pituitary content and blood concentration of PRL increased to maximal values, epididymal, vesicular gland and bulbourethral gland weights increased 6-fold, and body weight doubled. Between 150 and 200 days of age, testosterone concentration increased considerably (8 ng/ml), as did LH-pulse frequency and the amount of LH- and FSH- binding in the testis; the reproductive organs continued to grow at a rate faster than that of the body as a whole. Testicular development of ram lambs was accompanied by increases in the secretion of all three pituitary hormones with gonadotropic properties, and in the number of LH and FSH receptors.
Yarney
T A
TA
McGill University Centre for the Study of Reproduction, Department of Animal Science, Macdonald College, Ste Anne de Bellevue, Quebec.
Sanford
L M
LM
D000818:Animals; D001835:Body Weight; D005640:Follicle Stimulating Hormone / Q000032:analysis / Q000097:blood / Q000378:metabolism*; D007986:Luteinizing Hormone / Q000032:analysis / Q000097:blood / Q000378:metabolism*; D008297:Male; D009929:Organ Size; D010902:Pituitary Gland / Q000033:anatomy & histology / Q000254:growth & development*; D011388:Prolactin / Q000032:analysis / Q000097:blood / Q000378:metabolism*; D012741:Sexual Maturation; D012756:Sheep / Q000254:growth & development*; D013737:Testis / Q000033:anatomy & histology / Q000254:growth & development*; D013739:Testosterone / Q000097:blood
D013739:Testosterone; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone