[Rapid development of liver cirrhosis following acute non-A, non-B hepatitis].
Four cases of shortly developed liver cirrhosis as consequence of non-A-non-B-hepatitis are described. Liver cirrhosis was diagnosed by liver histology at days 254, 298, 651 and 891 after acute infection, respectively. For the first time a normal liver histology was documented in one case immediately before infection together with follow up biopsies of chronic hepatitis up to liver cirrhosis (day 891) after acute posttransfusion non-A-non-B-hepatitis. Further 20 cases with liver cirrhosis are described in the literature having developed between 90 and 2190 days after acute non-A-non-B-hepatitis. It is concluded that non-A-non-B-hepatitis has to be concerned as a serious etiological factor of liver cirrhosis developing shortly after acute infection.
Huth
M
M
Med. Klinik I, Kliniken der Stadt Saarbrücken.
Liehr
H
H
Spech
H J
HJ
D000208:Acute Disease; D001706:Biopsy; D005500:Follow-Up Studies; D006526:Hepatitis C / Q000150:complications* / Q000473:pathology; D006521:Hepatitis, Chronic / Q000473:pathology; D006525:Hepatitis, Viral, Human / Q000150:complications*; D006801:Humans; D008099:Liver / Q000473:pathology; D008103:Liver Cirrhosis / Q000473:pathology*; D008297:Male; D008875:Middle Aged
Rasche Entwicklung einer Leberzirrhose nach akuter Hepatitis Non-A-Non-B.