title: Adequacy of haemodiafiltration.
abstract: In this study we have evaluated the influence of blood and ultrafiltration flow rate on the performance of five different high-flux membrane dialysers during haemodiafiltration. On the basis of clearance data we optimised the haemodiafiltration schedule of six uraemic patients to maintain an adequate midweek blood urea nitrogen concentration, while reducing the treatment time from 285 +/- 23 min to 210 min. After a follow-up of 6 months, we observed no difference in the clinical tolerance or in the biochemical parameters, compared to those found during the preceding haemodialysis period. Our data confirm the suggestions of other authors that haemodiafiltration is an effective alternative to conventional haemodialysis.
authors.affiliation: Renal Unit, Ospedale Maggiore, Lodi, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Surian
authors.forename: F
authors.initials: F
authors.lastname: Malberti
authors.forename: B
authors.initials: B
authors.lastname: Corradi
authors.forename: G
authors.initials: G
authors.lastname: Orlandini
authors.forename: E
authors.initials: E
authors.lastname: Varini
authors.forename: G
authors.initials: G
authors.lastname: Colussi
authors.forename: L
authors.initials: L
authors.lastname: Minetti
mesh_terms: D000328:Adult; D000368:Aged; D003404:Creatinine / Q000378:metabolism; D015314:Dialysis Solutions / Q000378:metabolism; D005069:Evaluation Studies as Topic; D005500:Follow-Up Studies; D006440:Hemofiltration / Q000295:instrumentation / Q000592:standards*; D006801:Humans; D007444:Inulin / Q000378:metabolism; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D006435:Renal Dialysis / Q000295:instrumentation / Q000592:standards; D014508:Urea / Q000378:metabolism
chemical_list: D015314:Dialysis Solutions; D008567:Membranes, Artificial; D014508:Urea; D007444:Inulin; D003404:Creatinine