[The effect of ginseng stem, leaf and rhizoma saponins on the formation of lipid peroxides in rats of various ages].
The effect of saponins isolated from the stem, leaf and rhizoma of panax ginseng on the formation of lipid peroxides in aged (30, 24 and 20 months) and middle-aged (14 months) wistar rats was studied with both in vivo and in vitro methods. The results showed: The formation of lipid peroxides increased with age in rats and mice: the two saponins of ginseng stem, leaf and rhizoma can obviously inhibit the lipid peroxidation in the serum (plasma) and liver homogenate of aged and middle-aged rats (p less than 0.05 and less than 0.001). The same effect was also shown in the aged LACA mouse (18 months) experiment.
Sun
W J
WJ
Ma
N
N
Ma
L X
LX
Zhang
Y L
YL
Feng
W L
WL
D000375:Aging / Q000187:drug effects*; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D005609:Free Radicals; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D051379:Mice; D005894:Panax; D010946:Plants, Medicinal; D051381:Rats; D011919:Rats, Inbred Strains; D012503:Saponins / Q000494:pharmacology*
D004365:Drugs, Chinese Herbal; D005609:Free Radicals; D012503:Saponins