title: [Studies of two cases of ruptured intracranial aneurysm with disseminated intravascular coagulation].
abstract: Two cases of ruptured intracranial aneurysm with severe DIC were reported. One case recovered due to early treatment. A 65-year-old man was admitted to our hospital in June, 1987 because he was suffering from sudden severe headache and nausea. On admission, CT-scan angiograms disclosed moderate subarachnoid hemorrhage (SAH) and probable ruptured anterior communicating aneurysm. However definitive diagnosis was not made at that time. On the 15th day after SAH, he had high fever and low blood arterial pressure. His laboratory findings were consistent with DIC, and therapy of FOY was then started with transfusion of fresh blood two days after. His laboratory findings and clinical status improved gradually and he underwent uneventful operation of the aneurysm on the 42nd day after SAH. Another case concerns a 71-year-old woman who was admitted to our hospital in June, 1988 because she had lost consciousness. On admission, CT-scan disclosed severe SAH and next day an operation was performed. On the 6th day after SAH, she showed clinical and laboratory evidence of severe DIC and died two days later. The association between DIC and ruptured intracranial aneurysms have been rarely mentioned in past reports. But the association might occur more frequently than we have supposed, and so more immediate and careful diagnosis and proper treatment for DIC should be given.
authors.affiliation: Department of Neurosurgery, Central Gunma Neurosurgical Hospital, Japan.
authors.forename: O
authors.initials: O
authors.lastname: Toyoda
authors.forename: K
authors.initials: K
authors.lastname: Nojiri
authors.forename: H
authors.initials: H
authors.lastname: Nakajima
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D004211:Disseminated Intravascular Coagulation / Q000150:complications* / Q000188:drug therapy; D005260:Female; D016670:Gabexate; D006146:Guanidines / Q000627:therapeutic use; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications* / Q000601:surgery; D008297:Male; D012422:Rupture, Spontaneous; D013345:Subarachnoid Hemorrhage / Q000209:etiology
chemical_list: D000925:Anticoagulants; D006146:Guanidines; D016670:Gabexate