title: [Preparation and evaluation of an internal reference of oral polio vaccine].
abstract: A trivalent working reference preparation for oral poliovaccine was prepared, and assayed over a period of three years; its stability at different temperatures was investigated. The results show that the batch of cryotubes is homogeneous and stable when stored frozen. The preparation, while containing no stabilizer is similar in composition with the vaccines to be tested and suitable to judge the acceptability of assays. The test system was shown to be accurate and reproducible.
authors.affiliation: Département de Microbiologie, Institut d'Hygiène et d'Epidémiologie.
authors.forename: J
authors.initials: J
authors.lastname: Husson-van Vliet
authors.forename: P E
authors.initials: PE
authors.lastname: Lemoine
mesh_terms: D004355:Drug Stability; D006801:Humans; D011055:Poliovirus Vaccine, Oral / Q000032:analysis* / Q000592:standards; D012015:Reference Standards; D013696:Temperature; D013997:Time Factors
chemical_list: D011055:Poliovirus Vaccine, Oral
vernacular_title: Préparation et évaluation d'une référence interne de vaccin polio oral.