title: Monitoring of murine feto-placental growth by pregnancy-specific serum proteins in an experimentally induced fetal growth retardation model.
abstract: Fetal growth retardation was induced in 14 day pregnant female mice by ligation of the uterine arteries. Maternal serum levels of pregnancy-associated murine protein-2 (PAM-2) and murine alpha-fetoprotein (m-AFP) were recorded. The ligation resulted in a reduction in fetal growth and a corresponding decrease in maternal circulatory m-AFP, whereas placental growth and maternal circulating PAM-2 were not significantly affected.
authors.affiliation: Department of Veterinary Pathology, Royal Veterinary and Agricultural University, Copenhagen, Fredriksberg, Denmark.
authors.forename: L L
authors.initials: LL
authors.lastname: Andersen
authors.forename: O M
authors.initials: OM
authors.lastname: Poulsen
authors.forename: J
authors.initials: J
authors.lastname: Hau
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000097:blood; D005260:Female; D005317:Fetal Growth Retardation / Q000097:blood / Q000175:diagnosis / Q000503:physiopathology*; D005333:Fetus / Q000502:physiology*; D051379:Mice; D008815:Mice, Inbred Strains; D010920:Placenta / Q000503:physiopathology*; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000032:analysis*; D000509:alpha-Fetoproteins / Q000032:analysis*
chemical_list: D015415:Biomarkers; D011257:Pregnancy Proteins; D000509:alpha-Fetoproteins; C048775:pregnancy-associated murine protein 2