Beta 2-microglobulin kinetics in an ovine model.
The kinetics of 125I-beta 2 microglobulin (beta 2M) and 51Cr-EDTA were measured in normal and nephrectomized sheep. In normal sheep the beta 2M clearance was similar to that of EDTA (i.e., glomerular filtration rate), as were the distribution volumes. In anephric sheep the beta 2M clearance was 7.7 +/- 1.4 ml/min.
Odell
R A
RA
Centre for Biomedical Engineering, University of New South Wales, Kensington, Australia.
Slowiazcek
P
P
Schindhelm
K
K
D000818:Animals; D004492:Edetic Acid / Q000493:pharmacokinetics; D005919:Glomerular Filtration Rate / Q000502:physiology*; D008970:Molecular Weight; D009392:Nephrectomy; D011485:Protein Binding; D012756:Sheep; D001613:beta 2-Microglobulin / Q000378:metabolism*
D001613:beta 2-Microglobulin; D004492:Edetic Acid