title: Evaluation of restriction endonuclease analysis as an epidemiologic typing system for Branhamella catarrhalis.
abstract: Restriction endonuclease analysis (REA) was evaluated as an epidemiologic typing tool to distinguish Branhamella catarrhalis strains. Fourteen beta-lactamase-producing strains were collected over a 16-month period at a hospital where a nosocomial outbreak of this organism was previously documented by REA. REA produced 12 distinct patterns which correlated with epidemiologic data. Chromosomal REA appears to be a useful technique for distinguishing B. catarrhalis strains.
authors.affiliation: Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06510.
authors.forename: J E
authors.initials: JE
authors.lastname: Patterson
authors.forename: T F
authors.initials: TF
authors.lastname: Patterson
authors.forename: P
authors.initials: P
authors.lastname: Farrel
authors.forename: W J
authors.initials: WJ
authors.lastname: Hierholzer
authors.forename: M J
authors.initials: MJ
authors.lastname: Zervos
mesh_terms: D001424:Bacterial Infections / Q000453:epidemiology / Q000382:microbiology*; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D004269:DNA, Bacterial / Q000032:analysis*; D004196:Disease Outbreaks; D004587:Electrophoresis, Agar Gel; D006801:Humans; D001936:Moraxella catarrhalis / Q000145:classification* / Q000235:genetics; D000091402:Prohibitins; D015183:Restriction Mapping; D012189:Retrospective Studies
chemical_list: D004269:DNA, Bacterial; C000717331:PHB2 protein, human; D000091402:Prohibitins