title: [The induction and elimination of cytogenetic disorders in monkey lymphocytes following thiophosphamide action].
abstract: The dynamics of sister chromatid exchanges and chromosome aberrations in lymphocyte of monkey has been investigated after a thiophosphamide exposure. The process of induction and elimination of cytogenetic damages was described by the mathematical model. Developing the model in detail will allow to make a cytogenetic prognosis of remote consequences of mutagenic exposure.
authors.forename: S M
authors.initials: SM
authors.lastname: Kuzin
authors.forename: S V
authors.initials: SV
authors.lastname: Stukalov
authors.forename: V V
authors.initials: VV
authors.lastname: Viktorov
authors.forename: Z A
authors.initials: ZA
authors.lastname: Dzhemilev
authors.forename: P G
authors.initials: PG
authors.lastname: Popandopulo
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D008214:Lymphocytes / Q000187:drug effects* / Q000648:ultrastructure; D008253:Macaca mulatta; D008297:Male; D008433:Mathematics; D008957:Models, Genetic; D012854:Sister Chromatid Exchange / Q000187:drug effects; D013852:Thiotepa / Q000633:toxicity*; D013997:Time Factors
chemical_list: D013852:Thiotepa
vernacular_title: Induktsiia i éliminatsiia tsitogeneticheskikh narusheniĭ v limfotsitakh obez'ian posle vozdeĭstviia tiofosfamidom.