[Transient Parkinson syndrome and tremor caused by the use of sodium valproate].
From 1986 till 1988, 88 patients received sodium valproate for the first time as a therapy for epilepsy. One of them developed a fine tremor, three a coarse tremor with a cogwheel phenomenon, two developed a full parkinsonian syndrome. All these symptoms in these six patients disappeared completely or nearly completely after changing to another anti-epileptic drug or reducing the dose.
van der Zwan
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A
D000368:Aged; D004827:Epilepsy / Q000188:drug therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010302:Parkinson Disease, Secondary / Q000139:chemically induced*; D014635:Valproic Acid / Q000009:adverse effects* / Q000627:therapeutic use
D014635:Valproic Acid
Voorbijgaand Parkinson-syndroom en tremor door gebruik van natriumvalproaat.