title: Foci of increased T2 signal intensity on brain MR scans of healthy elderly subjects.
abstract: Foci of increased T2 signal intensity were found on brain MR scans in 16 (59%) of 27 healthy elderly volunteer subjects, ages 63 to 86 years old. These foci were not related to cognitive function or cerebrovascular risk factors; instead, they were highly correlated to age, being present in 11 of 11 subjects aged 75 years and over.
authors.affiliation: Department of Psychiatry, Indiana University School of Medicine, Indianapolis 46223.
authors.forename: H C
authors.initials: HC
authors.lastname: Hendrie
authors.forename: M R
authors.initials: MR
authors.lastname: Farlow
authors.forename: M G
authors.initials: MG
authors.lastname: Austrom
authors.forename: M K
authors.initials: MK
authors.lastname: Edwards
authors.forename: M A
authors.initials: MA
authors.lastname: Williams
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000473:pathology* / Q000523:psychology; D001921:Brain / Q000473:pathology*; D002561:Cerebrovascular Disorders / Q000209:etiology; D003071:Cognition; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000175:diagnosis; D012307:Risk Factors