[Barotrauma in guinea pigs--stimulated tests of diving].
For a systematic understanding of the effect of diving on hearing ability and middle and inner ear morphology, we have carried out simulated tests on 65 healthy guinea pigs, under water 60 meters deep, and then decompress rapidly. The tests proved that hearing ability changed most significantly 7 days after diving. After diving, all tympanogram curves, except those in 3 ears, changed to type B. Thirty-nine (37.85%) middle ears had been damaged, 4 (3.88%) had inner ears injured, as seen under light microscope. During decompression, three animals had nystagmus. Screen electronmicroscopy showed hair cell destruction and hair derangement. Transmission electronmicroscopy showed mitochondria damage. The results showed that damages in middle and inner ears were mainly mechanical, sometimes metabolic.
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D000818:Animals; D001309:Auditory Threshold; D001469:Barotrauma / Q000503:physiopathology*; D003665:Decompression Sickness / Q000209:etiology; D004242:Diving / Q000293:injuries*; D007758:Ear, Inner / Q000293:injuries*; D004432:Ear, Middle / Q000293:injuries*; D006168:Guinea Pigs; D009759:Nystagmus, Pathologic / Q000209:etiology