title: Clinical significance of urine ferritin determination in urologic malignancies.
abstract: Urine and serum ferritin levels were measured by a double-antibody radio-immunoassay in 96 normal adults and 57 patients with urologic malignancies. In the 96 adults, the urine ferritin levels ranged from 0 to 28 ng/ml. Elevated urine ferritin levels were observed in all 7 patients with renal pelvic carcinoma, 4 of 13 patients with renal carcinoma, 1 of 13 patients with well-differentiated (Grade I) bladder carcinoma, 8 of 19 patients with median-differentiated (Grade II) bladder carcinoma, and all 5 patients with poorly-differentiated (Grades III, IV) bladder carcinoma. These results indicated that urine ferritin assay was helpful in discriminating well-differentiated bladder carcinoma from the poorly-differentiated (P less than 0.01) in addition to differentiating renal pelvic carcinoma from renal carcinoma (P less than 0.05).
authors.forename: D J
authors.initials: DJ
authors.lastname: Tang
authors.forename: X Y
authors.initials: XY
authors.lastname: Fan
authors.forename: X B
authors.initials: XB
authors.lastname: Huang
authors.forename: P H
authors.initials: PH
authors.lastname: Chen
authors.forename: Y
authors.initials: Y
authors.lastname: Liang
authors.forename: Y M
authors.initials: YM
authors.lastname: Lang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005293:Ferritins / Q000652:urine*; D006801:Humans; D007680:Kidney Neoplasms / Q000652:urine*; D007682:Kidney Pelvis; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D001749:Urinary Bladder Neoplasms / Q000652:urine*
chemical_list: D005293:Ferritins