title: Immunohistochemical detection of a substance resembling growth hormone-releasing factor in the brain of the rainbow trout (Salmo gairdneri).
abstract: We studied the distribution of an immunoreactive substance resembling growth hormone-releasing factor (GRF) in the hypothalamus and pituitary gland of the rainbow trout by immunofluorescence methods. The GRF-like immunoreactive perikaryon was observed in colchicine-treated fish. The majority of GRF-containing neurons were located in the nucleus lateral tuberis; others were located in the caudal part of the preoptic nucleus of the hypothalamus. The GRF-like immunoreactive neuronal processes projected into the pars distalis via the pars nervosa of the pituitary gland. The distribution of the GRF-like immunoreactive substance in the hypothalamus and pituitary gland suggests that GRF plays a physiological role in the regulation of growth hormone release from the pituitary gland of rainbow trout, as it does in mammals.
authors.affiliation: Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
authors.forename: D
authors.initials: D
authors.lastname: Luo
authors.forename: B A
authors.initials: BA
authors.lastname: McKeown
mesh_terms: D000818:Animals; D001923:Brain Chemistry; D005455:Fluorescent Antibody Technique; D013007:Growth Hormone-Releasing Hormone / Q000032:analysis*; D009474:Neurons / Q000032:analysis; D010902:Pituitary Gland / Q000032:analysis*; D014337:Trout
chemical_list: D013007:Growth Hormone-Releasing Hormone