[A study on amino acid solutions for postoperative parenteral nutrition--evaluation in terms of surgical stress, amino acid composition and its doses].
A newly composed amino acid solution, which contained a 30% branched-chain amino acid (BCAA), and a standard amino acid solution containing 22.6% BCAA were used for total parenteral nutrition following operation of the digestive organs. Their nutritional effects were evaluated by surgical stress (thoracotomy group or non-thoracotomy group) according to the two steps of amino acid doses (1.2g/kg/day administration group or 1.6g/kg/day group). 1. No significant differences could be recognized in an improvement in the serum proteins following administration of BCAA-enriched solution either in the thoracotomy or in the non-thoracotomy group. 2. An improvement in BCAA/AAA molar ratio was seen on the plasma aminogram following administration of BCAA-enriched solution both in the thoracotomy and in the non-thoracotomy groups. 3. No improvement in nitrogen balance following administration of BCAA-enriched solution could be found in the thoracotomy group, while its improving trend was recognized in the non-thoracotomy group treated with 1.6g/kg/day of the amino acid. 4. Neither in the thoracotomy nor in the non-thoracotomy group any significant inhibition of the excreted volumes of urinary 3-methylhistidine could be recognized.
Kawai
C
C
First Department of Surgery, Niigata University School of Medicine, Japan.
D000597:Amino Acids, Branched-Chain / Q000008:administration & dosage*; D001798:Blood Proteins / Q000032:analysis; D006801:Humans; D008762:Methylhistidines; D009584:Nitrogen / Q000378:metabolism; D010289:Parenteral Nutrition, Total; D011182:Postoperative Care; D013908:Thoracotomy
D000597:Amino Acids, Branched-Chain; D001798:Blood Proteins; D008762:Methylhistidines; C028118:3-methylhistidine; D009584:Nitrogen