title: Identity of alanine:glyoxylate aminotransferase with alanine:2-oxoglutarate aminotransferase in rat liver cytosol.
abstract: Rat liver soluble fraction contained 3 forms of alanine: glyoxylate aminotransferase. One with a pI of 5.2 and an Mr of approx. 110,000 was found to be identical with cytosolic alanine:2-oxoglutarate aminotransferase. The pI 6.0 enzyme with an Mr of approx. 220,000 was suggested to be from broken mitochondrial alanine:glyoxylate aminotransferase 2 and the pI 8.0 enzyme with an Mr of approx. 80,000 enzyme from broken peroxisomal and mitochondrial alanine:glyoxylate aminotransferase 1. These results suggest that the cytosolic alanine: glyoxylate aminotransferase activity is due to cytosolic alanine: 2-oxoglutarate aminotransferase.
authors.affiliation: Department of Oral Anatomy, Kyushu Dental College, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: S
authors.initials: S
authors.lastname: Hayashi
authors.forename: S
authors.initials: S
authors.lastname: Fujiwara
authors.forename: T
authors.initials: T
authors.lastname: Noguchi
mesh_terms: D000410:Alanine Transaminase / Q000032:analysis*; D000818:Animals; D003600:Cytosol / Q000201:enzymology; D007525:Isoelectric Focusing; D007527:Isoenzymes / Q000032:analysis*; D008099:Liver / Q000201:enzymology*; D008297:Male; D051381:Rats; D012995:Solubility; D013816:Thermodynamics; D000637:Transaminases
chemical_list: D007527:Isoenzymes; D000637:Transaminases; D000410:Alanine Transaminase; C019635:Alanine-glyoxylate transaminase