title: [Use of nitroglycerin to prevent arterial hypertension during general anesthesia using ketamine].
abstract: Central hemodynamics was studied in 82 patients during surgery performed under various types of general intravenous ketamine anesthesia. Ketamine was shown to have a stimulating effect on hemodynamics both alone and in combinations with droperidol and diazepam. Single intravenous injection (0.25 mg) or drip infusion (0.3 micrograms/(kg.min) of nitroglycerin effectively prevented arterial hypertension, decreased peripheral vascular resistance and myocardial oxygen demand.
authors.forename: V A
authors.initials: VA
authors.lastname: Novozhilov
mesh_terms: D000328:Adult; D000768:Anesthesia, General; D000771:Anesthesia, Intravenous; D006801:Humans; D006973:Hypertension / Q000517:prevention & control*; D007649:Ketamine / Q000008:administration & dosage / Q000009:adverse effects*; D008875:Middle Aged; D005996:Nitroglycerin / Q000627:therapeutic use*
chemical_list: D007649:Ketamine; D005996:Nitroglycerin
vernacular_title: Primenenie nitroglitserina dlia profilaktika arterial'noĭ gipertenziipri obshcheĭ anestezii ketaminom.