[Albendazole in the treatment of hepatic and intra-abdominal hydatidosis].
Albendazole, in doses of 10 mg/kg/day for 28 days with 14 days rest periods between series and series, with a minimum of 3 and a maximum 6 series was administered to 16 patients, 13 women and 3 men, with hepatic and/or of the abdominal cavity hydatid cysts. Clinical, immunological and ultrasonographic criterion were used to evaluate the response, obtaining the following results: complete cure in 6 patients (37.5%), improvement in 7 patients (43.7%) and without change in 3 (18.7%). Drug was tolerated, occurring only one case of reversible total alopecia. There were not abnormalities in liver and renal function tests or in the haematological indices. As conclusion, Albendazole is a good therapeutic alternative in cases of inoperable or multiple hydatid cysts.
Vildósola
H
H
Sanchéz
L
L
Espinoza
R
R
D000005:Abdomen; D000328:Adult; D000368:Aged; D015766:Albendazole / Q000009:adverse effects / Q000627:therapeutic use*; D004341:Drug Evaluation; D004443:Echinococcosis / Q000188:drug therapy*; D004444:Echinococcosis, Hepatic / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012074:Remission Induction
D015766:Albendazole
Albendazol en el tratamiento de la hidatidosis hepática e intrabdominal.