title: Regulatory detoxication responses in Gobiidae experimentally exposed to PCBs.
abstract: In order to investigate interspecific responses to pollutants, physiological and biochemical parameters were studied in two species of Gobiidae under both natural and experimental conditions. Gobius niger, collected in a polluted area, had higher mixed function oxidases activity and polychlorobiphenyl (PCB) residues than another species, Zosterisessor ophiocephalus, collected from a relatively clean lagoon. After acclimatization to clean water and exposure to PCBs (Aroclor 1260), both species showed responses similar to those observed in the field and all biochemical parameters related to detoxication were much higher in G. niger. This suggests that this species undergoes metabolic or genetic adaptation.
authors.affiliation: Dipartimento di Biologia Ambientale, Università di Siena, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Fossi
authors.forename: C
authors.initials: C
authors.lastname: Leonzio
authors.forename: S
authors.initials: S
authors.lastname: Focardi
mesh_terms: D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004781:Environmental Exposure; D005260:Female; D005399:Fishes / Q000378:metabolism*; D008658:Inactivation, Metabolic; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology; D006899:Mixed Function Oxygenases / Q000378:metabolism; D010105:Oxygenases / Q000378:metabolism; D011078:Polychlorinated Biphenyls / Q000494:pharmacology*
chemical_list: D003577:Cytochrome P-450 Enzyme System; D011078:Polychlorinated Biphenyls; D006899:Mixed Function Oxygenases; D010105:Oxygenases