title: [Interaction of block-polyurethane containing lactose linkages and immobilized beta-galactosidase with body tissues].
abstract: Biodegradation of the polymeric composition containing immobilized beta-galactosidase after implantation and its effect on the surrounding tissues are examined. Immunogenicity of the composition is studied by the method of the immunoenzymic analysis. Activation of the immune system is shown to occur in the process of the composition degradation.
authors.forename: O S
authors.initials: OS
authors.lastname: Shevchenko
authors.forename: E M
authors.initials: EM
authors.lastname: Kavun
authors.forename: M V
authors.initials: MV
authors.lastname: Skok
authors.forename: O I
authors.initials: OI
authors.lastname: Sniegir'ov
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D004800:Enzymes, Immobilized; D005696:Galactosidases / Q000378:metabolism*; D007124:Immunoenzyme Techniques; D007785:Lactose / Q000378:metabolism*; D051379:Mice; D011140:Polyurethanes / Q000378:metabolism*; D001616:beta-Galactosidase / Q000378:metabolism*
chemical_list: D004800:Enzymes, Immobilized; D011140:Polyurethanes; D000135:Acid Phosphatase; D005696:Galactosidases; D001616:beta-Galactosidase; D007785:Lactose
vernacular_title: Vzaiemodiia bloksopoliuretanu, shcho mistit' laktozy ta immobilizovanu beta-galaktozidazu, iz tkaninami organizmu.