Differentiation in vitro of neural precursor cells from normal and Pecanex mutant Drosophila embryos.
Early gastrula embryos, lacking both maternally and zygotically expressed activity of the neurogenic pecanex locus, are shown to contain a greater than wild-type number of stably determined neural precursor cells which can differentiate into neurons in culture.
LaBonne
S G
SG
Department of Developmental Genetics and Anatomy, Case Western Reserve University Cleveland, Ohio 44106.
Furst
A
A
D000818:Animals; D002454:Cell Differentiation; D002478:Cells, Cultured; D004331:Drosophila melanogaster / Q000196:embryology / Q000235:genetics*; D004625:Embryo, Nonmammalian / Q000166:cytology; D005775:Gastrula / Q000166:cytology; D009154:Mutation; D009420:Nervous System / Q000196:embryology; D009474:Neurons / Q000166:cytology*; D013045:Species Specificity