title: [Prevention of dysbacteriosis in the early neonatal period using a pure culture of acidophilic bacteria].
abstract: In order to prevent dysbacterioses occurring in the early neonatal period, 60 neonates classified with the risk group were administered, when they were still at the puerperal room, pure cultures of specially selected strains of Lactobacillus acidophilus possessing marked anti-Klebsiella activity and antagonistic activity against Staphylococcus aureus. The cultures were instilled into the mouth and nasal passages. Forty neonates administered bifidum-bacterin and 54 neonates not given biopreparations were used as control. Application of the pure culture of Lactobacillus acidophilus noticeably raised the efficacy of the preventive measures. Over 60 percent of the neonates were discharged from the maternity home with a normally formed intestinal microflora, 60 percent had normal microflora in the fauces, 80 percent in the nose, and 70 percent of the neonates demonstrated normal skin microflora. The carriage of opportunistic microorganisms in the fauces and nose of the neonates had decreased substantially by the time of the discharge from the maternity home, while the incidence of pyo-inflammatory diseases had also reduced among them.
authors.forename: P S
authors.initials: PS
authors.lastname: Moshchich
authors.forename: L I
authors.initials: LI
authors.lastname: Chernyshova
authors.forename: E P
authors.initials: EP
authors.lastname: Bernasovskaia
authors.forename: O P
authors.initials: OP
authors.lastname: Sel'nikova
authors.forename: V P
authors.initials: VP
authors.lastname: Sargsian
mesh_terms: D000281:Administration, Intranasal; D000284:Administration, Oral; D000818:Animals; D000898:Antibiosis; D001644:Bifidobacterium / Q000502:physiology*; D004751:Enteritis / Q000517:prevention & control*; D006801:Humans; D007231:Infant, Newborn / Q000382:microbiology*; D007422:Intestines / Q000382:microbiology*; D007709:Klebsiella / Q000472:pathogenicity; D007710:Klebsiella Infections / Q000517:prevention & control*; D007779:Lactobacillus acidophilus / Q000502:physiology*; D051379:Mice; D009305:Nasopharynx / Q000382:microbiology*
vernacular_title: Profilaktika disbakteriozov rannego neonatal'nogo perioda s pomoshch'iu chistoĭ kul'tury atsidofil'nykh palochek.