[Changes in blood gas in severely burned patients with acute pulmonary insufficiency treated by high frequency ventilation (HFV)].
Since 1982, 39 cases suffering from severe burns with acute pulmonary insufficiency were treated by high frequency ventilation (HFV). Blood gas changes were observed in 15 cases with mean burn areas of 67.7% TBSA, among them, 10 cases complicated with inhalation injury. The indications for HFV treatment are: dyspnea, increase of respiratory rate (greater than 30 times/min.), and PaO2 less than 60 mmHg (8.00 KPa).


RESULTS
30 times of blood gas analysis were studied with or without HFV in 15 cases. The mean PaO2 value was 59.2 mmHg (7.89 KPa) without HFV, while the mean PaO2 value was 109.3 mmHg (14.57 KPa) with HFV. The difference was significant (P less than 0.01). Their results showed that HFV can improve ventilation and raise PaO2 value in severe burned patients with acute pulmonary insufficiency. The mean PaCO2 values were 33.6 mmHg (4.48 KPa) and 32.9 mmHg (4.39 KPa) respectively without HFV and with HFV, no significant difference was found (P greater than 0.05). There was no retention of CO2 in blood when HFV was used. The advantages of HFV were discussed in this paper. This study suggests that it is advisable to use HFV in severely burned patients with acute pulmonary insufficiency.
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D000328:Adult; D002056:Burns / Q000097:blood / Q000150:complications*; D002245:Carbon Dioxide / Q000097:blood; D005260:Female; D006612:High-Frequency Ventilation; D006801:Humans; D008297:Male; D010100:Oxygen / Q000097:blood*; D012131:Respiratory Insufficiency / Q000097:blood / Q000209:etiology / Q000628:therapy*
D002245:Carbon Dioxide; D010100:Oxygen