Repression of sporulation: isolation and characterization of repression-resistant mutants of Bacillus subtilis.
The sporulation of Bacillus subtilis B34 was repressed by 24 h if glutamine or ammonium chloride but not glutamate was added at late log phase (70 h) when glucose and glutamate were nearly exhausted. Glutamine-resistant mutants were isolated by selective heat treatment during the delay period induced by glutamine. Glutamine-resistant mutants showed cross resistance not only against ammonium chloride but also against glucose just as glucose-resistant mutants showed resistance against nitrogenous catabolites.
Bhaduri
S
S
Department of Biochemistry, University College of Science, Calcutta, India.
Bandyopadhyay
S
S
Bose
S K
SK
D000643:Ammonium Chloride / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects / Q000235:genetics / Q000502:physiology*; D004352:Drug Resistance, Microbial; D005947:Glucose / Q000494:pharmacology; D005971:Glutamates / Q000494:pharmacology; D005973:Glutamine / Q000494:pharmacology; D009154:Mutation; D013171:Spores, Bacterial
D005971:Glutamates; D000643:Ammonium Chloride; D005973:Glutamine; D005947:Glucose