Interferon-gamma-like immunoreactivity and T-cell marker expression in rat skeletal muscle fibres.
Interferon-gamma (IFN-gamma)-like-immunoreactivity was observed in subsets of rat skeletal muscle fibres with 3 different mouse monoclonal antibodies directed to rat IFN-gamma and a rabbit polyclonal anti-rat IFN-gamma-antibody. These strongly IFN-gamma-immunoreactive fibres also expressed antigen defining T-cells of the cytotoxic/suppressor phenotype (CD8) and major histocompatibility complex (MHC) class I antigen.
Nennesmo
I
I
Department of Cellular and Neuropathology, Karolinska Institutet, Huddinge Hospital, Sweden.
Olsson
T
T
Ljungdahl
A
A
Kristensson
K
K
Van der Meide
P H
PH
D000818:Animals; D000911:Antibodies, Monoclonal; D000945:Antigens, Differentiation, T-Lymphocyte / Q000378:metabolism*; D005786:Gene Expression Regulation; D007150:Immunohistochemistry; D007371:Interferon-gamma / Q000378:metabolism*; D008297:Male; D009132:Muscles / Q000276:immunology* / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains
D000911:Antibodies, Monoclonal; D000945:Antigens, Differentiation, T-Lymphocyte; D007371:Interferon-gamma