title: [Integration and amplification of plasmid DNA in the Bacillus subtilis chromosome].
abstract: Some Bacillus subtilis strains demonstrate a high degree of pHV14 and pP1251 plasmid integration into the chromosome (1.10(-1]. According to the data of genetical analysis the plasmids are integrated into several regions of the same chromosome. A significant plasmid amplification in the composition of chromosome is observed when breeding on an increasing chloramphenicol concentration (20-300 micrograms/ml). Both tandem repetitions and single plasmid DNA copies and their fragments are found in the bacterial chromosomal DNA.
authors.forename: T N
authors.initials: TN
authors.lastname: Shevchenko
authors.forename: E O
authors.initials: EO
authors.lastname: Timashova
authors.forename: V V
authors.initials: VV
authors.lastname: Fomin
authors.forename: G D
authors.initials: GD
authors.lastname: Telegeev
mesh_terms: D001412:Bacillus subtilis / Q000187:drug effects / Q000235:genetics*; D002701:Chloramphenicol / Q000494:pharmacology; D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial; D004247:DNA / Q000235:genetics*; D005784:Gene Amplification; D005819:Genetic Markers; D010957:Plasmids; D011995:Recombination, Genetic; D013045:Species Specificity; D014170:Transformation, Genetic
chemical_list: D005819:Genetic Markers; D002701:Chloramphenicol; D004247:DNA
vernacular_title: Integratsiia i amplifikatsiia plazmidnoI DNK v khromosome Bacillus subtilis.