title: Dapsone-induced haemolytic anaemia and agranulocytosis in a patient with normal glucose-6-phosphate-dehydrogenase activity.
abstract: A case of dapsone-induced severe haemolytic anaemia and agranulocytosis is described. A possible common pathogenic mechanism for the simultaneous occurrence of these side effects of dapsone therapy in a patient with normal glucose-6-phosphate-dehydrogenase activity is proposed.
authors.affiliation: Department of Clinical Medicine, School of Medicine, Ribeirão, Preto, Brazil.
authors.forename: M S
authors.initials: MS
authors.lastname: Figueiredo
authors.forename: B O
authors.initials: BO
authors.lastname: Pinto
authors.forename: M A
authors.initials: MA
authors.lastname: Zago
mesh_terms: D000368:Aged; D000380:Agranulocytosis / Q000139:chemically induced*; D000743:Anemia, Hemolytic / Q000139:chemically induced*; D003622:Dapsone / Q000009:adverse effects* / Q000378:metabolism; D005260:Female; D005954:Glucosephosphate Dehydrogenase / Q000032:analysis*; D006801:Humans
chemical_list: D003622:Dapsone; D005954:Glucosephosphate Dehydrogenase