The effect automotive exhaust exposure on the carcinogenicity of dipentylnitrosamine (DPN) in the respiratory tract of rats.
In this investigation rats were exposed to gasoline engine and diesel engine exhaust, respectively, and additionally treated with DPN in order to check the syncarcinogenic effects.
Heinrich
U
U
Fraunhofer-Institut für Toxikologie und Aerosolforschung, Hannover, FRG.
Peters
L
L
Fuhst
R
R
Mohr
U
U
D000818:Animals; D005260:Female; D005742:Gasoline / Q000009:adverse effects; D007680:Kidney Neoplasms / Q000139:chemically induced / Q000453:epidemiology; D008113:Liver Neoplasms / Q000139:chemically induced / Q000453:epidemiology; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000453:epidemiology; D009602:Nitrosamines / Q000633:toxicity*; D051381:Rats; D011919:Rats, Inbred Strains; D012137:Respiratory System / Q000187:drug effects*; D012142:Respiratory Tract Neoplasms / Q000139:chemically induced* / Q000453:epidemiology; D001335:Vehicle Emissions / Q000009:adverse effects*
D005742:Gasoline; D009602:Nitrosamines; D001335:Vehicle Emissions; C032849:N,N-diamylnitrosamine