title: Studies on circulation rate and flow model for external loop bioreactor.
abstract: We performed experiments in an external loop bioreactor 250 mm in diameter and 4500 mm in height. The variation in circulation rate Um was studied over a wide range of surface gas velocities (UG = 0-24.9 cm/s), and a bioreactor flow model was obtained. We developed a new method (i.e., an electrical conductivity tracking system) to measure circulation rate and solve the problem of measuring general circulation resistance. A theoretical formula for Um was derived for use in scaling up the bioreactor: [formula: see text]
authors.affiliation: Beijing Research Institute for Nutritional Resources.
authors.forename: K
authors.initials: K
authors.lastname: Liu
authors.forename: X Z
authors.initials: XZ
authors.lastname: Jiang
authors.forename: B Z
authors.initials: BZ
authors.lastname: Li
mesh_terms: D001709:Biotechnology / Q000295:instrumentation*; D004553:Electric Conductivity; D007700:Kinetics; D008962:Models, Theoretical