title: A family with X-linked ichthyosis and hypogonadism.
abstract: We describe the clinical, biochemical and ophthalmic findings in four closely related males with X-linked ichthyosis and hypogonadism. Recognition of this association is important for both paediatricians and paediatric dermatologists.
authors.affiliation: Hospital for Sick Children, London, United Kingdom.
authors.forename: M G
authors.initials: MG
authors.lastname: Pike
authors.forename: M
authors.initials: M
authors.lastname: Hammerton
authors.forename: J
authors.initials: J
authors.lastname: Edge
authors.forename: D J
authors.initials: DJ
authors.lastname: Atherton
authors.forename: D B
authors.initials: DB
authors.lastname: Grant
mesh_terms: D001192:Arylsulfatases / Q000172:deficiency; D002648:Child; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D008040:Genetic Linkage; D006801:Humans; D007006:Hypogonadism / Q000097:blood / Q000201:enzymology / Q000235:genetics*; D007057:Ichthyosis / Q000235:genetics*; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D043266:Steryl-Sulfatase; D013739:Testosterone / Q000097:blood; D014960:X Chromosome
chemical_list: D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D001192:Arylsulfatases; D043266:Steryl-Sulfatase