Clinical use of vasopressin analogues.
Since the pressor and antidiuretic properties of the native hormone were characterized, chemists have been working to synthesize vasopressin analogues selective for particular biologic activities. Desmopressin has had the longest clinical track record. Subsequently, three more analogues have been formulated and have found specific clinical application. Their actions and uses are reviewed.
Robertson
G L
GL
University of Chicago Pritzker School of Medicine.
Harris
A
A
D001791:Blood Platelet Disorders / Q000188:drug therapy; D006348:Cardiac Surgical Procedures; D003894:Deamino Arginine Vasopressin / Q000009:adverse effects / Q000627:therapeutic use*; D003919:Diabetes Insipidus / Q000188:drug therapy / Q000503:physiopathology; D006467:Hemophilia A / Q000188:drug therapy; D006801:Humans; D008103:Liver Cirrhosis / Q000188:drug therapy; D014511:Uremia / Q000188:drug therapy; D014842:von Willebrand Diseases / Q000188:drug therapy
D003894:Deamino Arginine Vasopressin