A family with X-linked ichthyosis and hypogonadism.
We describe the clinical, biochemical and ophthalmic findings in four closely related males with X-linked ichthyosis and hypogonadism. Recognition of this association is important for both paediatricians and paediatric dermatologists.
Pike
M G
MG
Hospital for Sick Children, London, United Kingdom.
Hammerton
M
M
Edge
J
J
Atherton
D J
DJ
Grant
D B
DB
D001192:Arylsulfatases / Q000172:deficiency; D002648:Child; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D008040:Genetic Linkage; D006801:Humans; D007006:Hypogonadism / Q000097:blood / Q000201:enzymology / Q000235:genetics*; D007057:Ichthyosis / Q000235:genetics*; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D043266:Steryl-Sulfatase; D013739:Testosterone / Q000097:blood; D014960:X Chromosome
D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D001192:Arylsulfatases; D043266:Steryl-Sulfatase