title: The possible role of pH changes during EDTA demineralization of teeth.
abstract: Demineralization of dentin is a dynamic process. The pH of EDTA solutions inside pulp cavities decreases as demineralization occurs. Increasing EDTA concentration from 0.1 mol/L to 0.5 mol/L causes a faster acid accumulation and a higher demineralization rate. The efficiency of EDTA solutions decreases as time goes on, probably because of the acid released from EDTAHNa3 (the predominating species under the neutral conditions). Not all the available EDTA reacts after a few hours. The so-called autolimitation might be due to this acidification of the EDTA solution.
authors.affiliation: Faculty of Dentistry, University of Chile, Santiago.
authors.forename: V
authors.initials: V
authors.lastname: Calvo Pérez
authors.forename: M E
authors.initials: ME
authors.lastname: Medina Cárdenas
authors.forename: U
authors.initials: U
authors.lastname: Sánchez Planells
mesh_terms: D000143:Acids; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003648:Decalcification Technique; D003786:Dental Pulp Cavity / Q000187:drug effects*; D003804:Dentin / Q000187:drug effects; D003808:Dentin Solubility / Q000187:drug effects; D004492:Edetic Acid / Q000494:pharmacology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D012388:Root Canal Irrigants / Q000494:pharmacology*
chemical_list: D000143:Acids; D012388:Root Canal Irrigants; D004492:Edetic Acid