title: Prevalence of PPNG strains & in vitro sensitivity pattern of Neisseria gonorrhoeae in Varanasi (Uttar Pradesh, India).
abstract: Forty one consecutive gonococcal isolates were tested by disc method for their sensitivity to penicillin and seven other antimicrobials. Nineteen (46.34%) strains of N. gonorrhoeae were found to be relatively resistant to penicillin (MIC over 0.25 IU/ml) including 2 (4.88%) strains with complete resistance to penicillin (MIC over 1 IU/ml). None of the gonococcal strains tested was penicillinase-producing (PPNG). A decline in the proportion of sensitive strains of gonococci with a non-significant rise in median value of MIC for penicillin from 2.16 IU/ml in 1980-81 to 2.52 IU/ml in 1986-87 and other antimicrobials was observed.
authors.forename: D
authors.initials: D
authors.lastname: Mishra
authors.forename: G
authors.initials: G
authors.lastname: Singh
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D008826:Microbial Sensitivity Tests; D009344:Neisseria gonorrhoeae / Q000187:drug effects* / Q000378:metabolism; D010400:Penicillin G / Q000494:pharmacology*; D010403:Penicillin Resistance; D010405:Penicillinase / Q000096:biosynthesis*
chemical_list: D000900:Anti-Bacterial Agents; D010405:Penicillinase; D010400:Penicillin G