[Value of determining the spectrum of blood serum fatty acids in evaluating increasing the effectiveness of antibiotic therapy of dysentery in children with prodigiozan and ephedrine].
One hundred and ninety one children with acute Sonne and Flexner dysentery were observed with respect to the disease process, immunity indices and blood serum fatty acid spectrum. 104 children were treated with monomycin alone and 87 children were treated with the antibiotic in combination with prodigiozan and ephedrine as immunostimulators. It was shown that the recovery terms in the patients treated with the use of the immunostimulators decreased as compared to the patients treated with the antibiotic alone. The fatty acid spectrum in the children treated with the use of the immunostimulators differed from that in the children treated without them by low levels of fatty acids of the C12:0 to C18:1 composition.
Vereshchagin
I A
IA
Zhuravleva
O D
OD
D000276:Adjuvants, Immunologic; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D004405:Dysentery, Bacillary / Q000188:drug therapy* / Q000276:immunology; D004809:Ephedrine / Q000008:administration & dosage*; D015643:Erythromycin Ethylsuccinate / Q000008:administration & dosage*; D005230:Fatty Acids, Nonesterified / Q000097:blood*; D006801:Humans; D007223:Infant; D011135:Polysaccharides, Bacterial / Q000008:administration & dosage*; D011354:Prodigiozan / Q000008:administration & dosage*; D012763:Shigella flexneri; D012764:Shigella sonnei
D000276:Adjuvants, Immunologic; D005230:Fatty Acids, Nonesterified; D011135:Polysaccharides, Bacterial; D015643:Erythromycin Ethylsuccinate; D011354:Prodigiozan; D004809:Ephedrine
Znachenie opredeleniia spektra zhirnykh kislot syvorotki krovi pri otsenke povysheniia èffektivnosti antibiotikoterapii prodigiozanom i efedrinom pri disenterii u deteĭ.