The role of airways hyperreactivity in the pathogenesis of obturative bronchitis in the youngest children.
For detection of airways hyperreactivity plethysmographic examinations were carried out in 50 children aged from 6 months to 3 years (mean age 18 months) with obturative bronchitis, in the period without symptoms, and in 17 children in the same age group with recurrent respiratory infections without evidence of obturation (control group). Striking hyperreactivity was found in 68% of the children with obturative bronchitis and in 29% of the children with recurrent respiratory infections. The challenge dose of carbachol was much lower in children with obturative bronchitis than in control children. In the conclusions it is stressed that plethysmographic examination is completely safe, and should be done more frequently in cases of respiratory disease in young children.
Koczyńska-Nowacka
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D001986:Bronchial Spasm / Q000150:complications; D001991:Bronchitis / Q000209:etiology*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010991:Plethysmography / Q000379:methods