[The effect of acetylcholine on shifts in the spatial synchronization of the cortical potentials in the rabbit evoked by the reversible interruption of the mammillary body connections].
To study the role of cholinergic transmitter system in the maintenance of sychronizing limbic influences, the dynamics of the spatial distribution of the changes of cross-correlation coefficients of rabbits EEG led by 24 electrodes, was estimated at application of acetylcholine solution to the visual cortical area in combination with anode polarization of mammillary bodies. Acetylcholine, which separate effect was connected with a restricted increase of the spatial synchronization of potentials, completely eliminated the effects of isolated polarization expressed in a significant decrease of a half of calculated correlation coefficients between EEGs of the visual and motor cortical areas. Nonspecific cholinergic synchronizing system is supposed to exist which is active under the conditions of the mammillo-thalamo-cortical connections being intact.
Kurova
N S
NS
Kulikov
M A
MA
Murav'ev
I V
IV
Iastrebtsov
A I
AI
D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D002540:Cerebral Cortex / Q000187:drug effects* / Q000502:physiology; D003344:Cortical Synchronization / Q000187:drug effects*; D004569:Electroencephalography / Q000187:drug effects*; D005071:Evoked Potentials / Q000187:drug effects / Q000502:physiology; D008297:Male; D008326:Mammillary Bodies / Q000502:physiology*; D011817:Rabbits; D011950:Receptors, Cholinergic / Q000187:drug effects / Q000502:physiology
D011950:Receptors, Cholinergic; D000109:Acetylcholine
Vliianie atsetilkholina na sdvigi prostranstvennoĭ sinkhronizatsii korkovykh potentsialov krolika, vyzvannye obratimym preryvvaniem sviazeĭ mammiliarnykh tel.