title: Influence of the carbohydrate moiety on the growth inhibitory activity and adhesiveness of 3T3 cell plasma membranes.
abstract: Treatment of 3T3 cell plasma membranes with glycosidase enzymes decreased their ability to inhibit cell growth and also decreased their binding to 3T3 cells. This suggests that carbohydrate is required for complete function of inhibitory activity and that inhibition is associated with membrane adhesion.
authors.affiliation: Boston University, Biological Sciences Center, Massachusetts 02215.
authors.forename: P J
authors.initials: PJ
authors.lastname: Higgins
authors.forename: S W
authors.initials: SW
authors.lastname: Peterson
mesh_terms: D000118:Acetylglucosaminidase / Q000494:pharmacology; D000818:Animals; D002241:Carbohydrates / Q000502:physiology*; D002448:Cell Adhesion; D002455:Cell Division / Q000187:drug effects; D002462:Cell Membrane / Q000187:drug effects / Q000502:physiology*; D005347:Fibroblasts / Q000502:physiology*; D006596:Hexosaminidases / Q000494:pharmacology; D008361:Mannosidases / Q000494:pharmacology; D051379:Mice; D009439:Neuraminidase / Q000494:pharmacology; D005644:alpha-L-Fucosidase / Q000494:pharmacology; D043323:alpha-Mannosidase; D001616:beta-Galactosidase / Q000494:pharmacology
chemical_list: D002241:Carbohydrates; D006596:Hexosaminidases; D008361:Mannosidases; D009439:Neuraminidase; D001616:beta-Galactosidase; D043323:alpha-Mannosidase; D005644:alpha-L-Fucosidase; D000118:Acetylglucosaminidase