Drug-induced chronic pigmented purpura.
A close correlation between purpuric reaction and drugs was observed in seven cases of chronic pigmented purpura. The patients developed purpuric lesions after taking certain drugs for more than 3 years, were thiamine propyldisulfide in 2 cases, and chlordiazepoxide in 1 case. The purpuric lesions stopped recurring after removal of the drugs in the rest of the cases. It is suggested that drugs are among the etiological factors in chronic pigmented purpura.
Nishioka
K
K
Katayama
I
I
Masuzawa
M
M
Yokozeki
H
H
Nishiyama
S
S
D000368:Aged; D002707:Chlordiazepoxide / Q000009:adverse effects*; D002908:Chronic Disease; D005260:Female; D005665:Furosemide / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000009:adverse effects*; D010859:Pigmentation Disorders / Q000139:chemically induced*; D011693:Purpura / Q000139:chemically induced*; D013831:Thiamine / Q000009:adverse effects / Q000031:analogs & derivatives*
D002707:Chlordiazepoxide; D005665:Furosemide; D005996:Nitroglycerin; C013294:prosultiamine; D013831:Thiamine