Effects of atropine and mecamylamine given locally into periaqueductal gray on bioelectrical activity of chosen brain structures of the rabbit.
Atropine (Atr) or mecamylamine (MeC) were administered locally into the periaqueductal gray (PAG) of rabbits with chronically implanted electrodes into the motor-sensory cortex (MSC) ventro-posterolateral thalamic nuclei (NVPL), PAG and midbrain reticular formation (MRF). Bioelectrical responses in the cortex and subcortical structures were analyzed automatically by means of Fast Fourier Transform and Autoregressive Method. Both Atr and Mec modified the activity in PAG, Atr had also the influence in MRF and MSC.
Kowalczyk
M
M
Department of Pharmacology and Toxicology, Military Institute of Hygiene and Epidemiology, Warsaw.
Rump
S
S
Blinowska
K
K
D000818:Animals; D001285:Atropine / Q000494:pharmacology*; D004594:Electrophysiology; D008297:Male; D008464:Mecamylamine / Q000494:pharmacology*; D009044:Motor Cortex / Q000187:drug effects / Q000502:physiology; D010487:Periaqueductal Gray / Q000187:drug effects* / Q000502:physiology; D011817:Rabbits; D012154:Reticular Formation / Q000187:drug effects / Q000502:physiology; D013787:Thalamic Nuclei / Q000187:drug effects / Q000502:physiology
D008464:Mecamylamine; D001285:Atropine