title: Patterns of cellular interactions during fruiting-body formation in Myxococcus xanthus.
abstract: Aggregation and mound formation during development of the myxobacterium Myxococcus xanthus were examined by scanning electron microscopy and light microscopy. Several complex patterns of multicellular associations were observed. These observations imply that complex, organized cell-cell interactions occur during the process of development. Examination of sliced aggregates revealed that, contrary to common perception, the process of sporulation commenced during mound formation rather than after the completion of mound morphogenesis. The morphogenesis of M. xanthus fruiting bodies is compared with the morphogenesis of fruiting bodies of other members of the Myxobacteriales previously described in the literature.
authors.affiliation: Department of Molecular and Cell Biology, University of California, Berkeley 94720.
authors.forename: K A
authors.initials: KA
authors.lastname: O'Connor
authors.forename: D R
authors.initials: DR
authors.lastname: Zusman
mesh_terms: D008855:Microscopy, Electron, Scanning; D009231:Myxococcales / Q000166:cytology / Q000254:growth & development* / Q000648:ultrastructure; D014741:Video Recording / Q000379:methods