title: Estradiol stimulates cadherin expression in rat granulosa cells.
abstract: We have investigated the ability of hormones to modulate cadherin expression by differentiating cells. Immunocytochemical and immunoblot techniques were employed to analyze the effects of estradiol and follicle-stimulating hormone on cadherin expression in rat granulosa cells. Estradiol was shown to stimulate the expression of cadherin by these cells. This is the first report of a hormone regulating the levels of cadherin in differentiating cells.
authors.affiliation: Department of Surgery, McGill University, Royal Victoria Hospital, Montreal, Quebec, Canada.
authors.forename: O W
authors.initials: OW
authors.lastname: Blaschuk
authors.forename: R
authors.initials: R
authors.lastname: Farookhi
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D015153:Blotting, Western; D015820:Cadherins / Q000378:metabolism*; D002449:Cell Aggregation / Q000187:drug effects; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D005455:Fluorescent Antibody Technique; D005640:Follicle Stimulating Hormone / Q000494:pharmacology; D006107:Granulosa Cells / Q000166:cytology / Q000378:metabolism*; D008969:Molecular Sequence Data; D051381:Rats
chemical_list: D015820:Cadherins; D004958:Estradiol; D005640:Follicle Stimulating Hormone