title: Acute erythroblastic leukemia. Cytological, cytogenetic and phenotypic studies in one case.
abstract: We report the clinical, cytological, immunophenotypic, and cytogenetic findings in one patient with acute erythroblastic leukemia. Blast cells were identified by their reactivity with the early erythroid antibodies FA6-152 and carbonic anhydrase I. The leukemic blasts had no specific differentiating features identifying them as erythroblasts even at an ultrastructural level. Cytogenetic studies revealed multiple chromosome aberrations: 45,XX,i(11q),-16,-17,-21,+der(21)t(21;?)(q22;?),+mar 1.
authors.affiliation: Servei d'Hematologia, Hospital de la Santa Creu i Sant Pau, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Soler
authors.forename: N
authors.initials: N
authors.lastname: Pujol-Moix
authors.forename: M A
authors.initials: MA
authors.lastname: Bosch
authors.forename: C
authors.initials: C
authors.lastname: Guanyabens
authors.forename: A
authors.initials: A
authors.lastname: Aventin
authors.forename: C
authors.initials: C
authors.lastname: Boque
authors.forename: S
authors.initials: S
authors.lastname: Brunet
mesh_terms: D000368:Aged; D002869:Chromosome Aberrations; D004920:Erythropoiesis; D005260:Female; D006801:Humans; D004915:Leukemia, Erythroblastic, Acute / Q000235:genetics / Q000276:immunology / Q000473:pathology*; D008854:Microscopy, Electron; D010641:Phenotype