HTLV-1 associated myelopathy in an HTLV-1 and HBV double carrier family: report of a case and the mode of vertical transmission of both viruses.
Osame et al. first described human T cell lymphotropic virus type 1 (HTLV-1) associated myelopathy (HAM) as a new clinical entity in 1986. A 23 year old female diagnosed as having HAM whose family had a high frequency of double virus infection with HTLV-1 and hepatitis B virus (HBV) gave reason to suspect mother-to-child transmission of both viruses. No clear coincidence in the mode of transmission of HTLV-1 and HBV was found. It is presumed that the mechanism of infection with HTLV-1 and HBV differ slightly.
Nakamura
F
F
Department of Internal Medicine, Hiroshima Memorial Hospital, Japan.
Kajihara
H
H
Nakamura
M
M
Sasaki
H
H
Kumamoto
T
T
Okada
K
K
D000328:Adult; D015153:Blotting, Western; D005260:Female; D015481:HTLV-I Antibodies / Q000032:analysis; D006509:Hepatitis B / Q000235:genetics / Q000635:transmission*; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D015493:Paraparesis, Tropical Spastic / Q000235:genetics / Q000635:transmission*; D010375:Pedigree
D015481:HTLV-I Antibodies; D006514:Hepatitis B Surface Antigens