title: Effect of handling of plasma samples on histamine radio-enzyme assay.
abstract: 1. Freeze-thawing of plasma samples increased the histamine level at physiological histamine concentrations as analyzed by radio-enzyme assay, but not by high performance liquid chromatography. 2. Heating of plasma samples decreased the histamine levels. 3. Enzymatic or non-enzymatic formation of histamine during handling of plasma samples was not detected. 4. Some albumin preparations contain histamine.
authors.affiliation: Department of Dermatology, University of Kuopio, Finland.
authors.forename: R J
authors.initials: RJ
authors.lastname: Harvima
authors.forename: I T
authors.initials: IT
authors.lastname: Harvima
authors.forename: E O
authors.initials: EO
authors.lastname: Kajander
authors.forename: I M
authors.initials: IM
authors.lastname: Penttilä
authors.forename: H
authors.initials: H
authors.lastname: Neittaanmäki
authors.forename: J E
authors.initials: JE
authors.lastname: Fräki
mesh_terms: D000328:Adult; D006631:Amine Oxidase (Copper-Containing); D004588:Electrophoresis, Cellulose Acetate; D005615:Freezing; D006632:Histamine / Q000097:blood*; D006640:Histidine Decarboxylase; D006358:Hot Temperature; D006801:Humans; D012016:Reference Values; D012588:Scintillation Counting / Q000379:methods; D013048:Specimen Handling
chemical_list: D006632:Histamine; D006631:Amine Oxidase (Copper-Containing); D006640:Histidine Decarboxylase