A correlation between the levels of phenobarbital, phenytoin and valproic acid in the blood serum and in saliva from children treated due to epilepsy.
Blood serum and saliva levels of phenobarbital, phenytoin and valproic acid were estimated in children treated due to epilepsy. The ratio between the levels of the above drugs in saliva and blood serum can be of importance in calculating approximated levels of the drugs without a need of inconvenient inserting of needle and taking blood in children.
Sobaniec
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D000293:Adolescent; D002648:Child; D004827:Epilepsy / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D010634:Phenobarbital / Q000032:analysis / Q000097:blood* / Q000627:therapeutic use; D010672:Phenytoin / Q000032:analysis / Q000097:blood* / Q000627:therapeutic use; D012463:Saliva / Q000737:chemistry*; D014635:Valproic Acid / Q000032:analysis / Q000097:blood* / Q000627:therapeutic use
D014635:Valproic Acid; D010672:Phenytoin; D010634:Phenobarbital