[Double-blind study of the effect of tiaprofenic acid in comparison with indomethacin in patients with degenerative joint diseases].
The research of the effect and tolerance of tiaprophenic acid comprised 32 patients (10 male and 22 female) aged 53.7 years on average. 16 patients were treated by tiaprophenic acid and the other 16 by indomethacin. Among them 23 patients suffered from gonarthrosis and 9 patients from coxarthrosis. The tested subjective and objective parameters were markedly improved in 66.7% and less well in further 10.4% of patients (a total of 77% examinees). Side-effects were more various and developed more frequently in patients treated by indomethacin.
Jajić
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Jajić
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D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use*; D007719:Knee Joint; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy*; D015207:Osteoarthritis, Hip / Q000188:drug therapy; D011422:Propionates / Q000627:therapeutic use*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D011422:Propionates; C021270:tiaprofenic acid; D007213:Indomethacin
Dvostruko-slijepo ispitivanje ucinka tiaprofenske kiseline u usporedbi s indometacinom u bolesnika s degenerativnom bolesti zglobova.