title: The influence of CO2 production and physiological deadspace on end-tidal CO2 during controlled ventilation: a study using a mechanical model.
abstract: A mechanical lung model was used to investigate the effect of varying carbon dioxide production and deadspace on the end-tidal carbon dioxide levels achieved during mechanical ventilation when using the Bain, Humphrey ADE, and circle systems. Both factors had significant influence on end-tidal carbon dioxide concentration and could result in values in excess of those considered acceptable in clinical practice. The implications of the results are discussed.
authors.affiliation: Magill Department of Anaesthetics, Westminster Hospital, London, U.K.
authors.forename: M A
authors.initials: MA
authors.lastname: Stockwell
authors.forename: W
authors.initials: W
authors.lastname: Bruce
authors.forename: N
authors.initials: N
authors.lastname: Soni
mesh_terms: D000764:Anesthesia, Closed-Circuit / Q000295:instrumentation*; D000768:Anesthesia, General / Q000295:instrumentation*; D000769:Anesthesia, Inhalation / Q000295:instrumentation*; D002245:Carbon Dioxide / Q000502:physiology*; D006801:Humans; D008176:Lung Volume Measurements; D008838:Microcomputers; D008953:Models, Anatomic; D012126:Respiratory Dead Space / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted; D013990:Tidal Volume / Q000502:physiology*; D012122:Ventilators, Mechanical
chemical_list: D002245:Carbon Dioxide