title: Effect of weight loss on thiazide produced erectile problems in men.
abstract: Thiazide-type diuretics frequently produce erectile dysfunction in men on a regular diet. However, men on a weight-loss diet have much less erectile dysfunction. Thiazide-type diuretics also produce erectile dysfunction in rats and interfere with normal copulation. The mechanism of the dysfunction and the favorable response to weight loss is unknown.
authors.affiliation: Department of Medicine, University of Mississippi Medical Center, Jackson.
authors.forename: H G
authors.initials: HG
authors.lastname: Langford
authors.forename: R W
authors.initials: RW
authors.lastname: Rockhold
authors.forename: S
authors.initials: S
authors.lastname: Wassertheil-Smoller
authors.forename: A
authors.initials: A
authors.lastname: Oberman
authors.forename: B R
authors.initials: BR
authors.lastname: Davis
authors.forename: M D
authors.initials: MD
authors.lastname: Blaufox
mesh_terms: D000818:Animals; D001581:Benzothiadiazines; D004232:Diuretics; D004353:Drug Evaluation, Preclinical; D006801:Humans; D006973:Hypertension / Q000178:diet therapy / Q000188:drug therapy; D007989:Libido / Q000187:drug effects; D008297:Male; D010410:Penile Erection / Q000187:drug effects*; D051381:Rats; D012735:Sexual Dysfunction, Physiological / Q000139:chemically induced / Q000517:prevention & control; D049993:Sodium Chloride Symporter Inhibitors / Q000009:adverse effects*; D015431:Weight Loss
chemical_list: D001581:Benzothiadiazines; D004232:Diuretics; D049993:Sodium Chloride Symporter Inhibitors