title: Epidemiological model and cost-effectiveness analysis of tuberculosis treatment programmes in Indonesia.
abstract: An epidemiological model of tuberculosis, based on the natural history of tuberculosis and the control programmes in Indonesia, was constructed. This model was used for estimating future tuberculosis-prevented cases and costs for three treatment strategies--the 100% standard course, the 100% short course, and the existing strategy (a combination of 65% standard course and 35% short course)--in accordance with the master plan of the Indonesian Government's tuberculosis control programme. A cost-effectiveness analysis of the three strategies confirmed that the short-course strategy was the most cost-effective. Sensitivity analysis, which applied a broad range of parameters, continued to confirm the short-course strategy as the most cost-effective. If the short-course strategy had been applied in 1980 instead of the existing strategy (using the most likely parameters), the short-course strategy would prevent 1.8 million sputum-positive cases and would save 61.0 million dollars by the year 2000.
authors.affiliation: Division of Chronic Disease Control, Centers for Disease Control, Atlanta, Georgia 30333.
authors.forename: M R
authors.initials: MR
authors.lastname: Joesoef
authors.forename: P L
authors.initials: PL
authors.lastname: Remington
authors.forename: P T
authors.initials: PT
authors.lastname: Jiptoherijanto
mesh_terms: D000995:Antitubercular Agents / Q000008:administration & dosage*; D003362:Cost-Benefit Analysis; D004359:Drug Therapy, Combination; D006801:Humans; D007214:Indonesia; D008962:Models, Theoretical; D009313:National Health Programs / Q000191:economics*; D012680:Sensitivity and Specificity; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy* / Q000191:economics / Q000453:epidemiology
chemical_list: D000995:Antitubercular Agents