The possibility of a healthy progeny in patients after acute lymphoblastic leukaemia.
Five patients, cured from acute lymphoblastic leukaemia (ALL), four women and one man, have seven healthy children: four girls and three boys. The children were born in the period from 13 to 25 years since the beginning of the disease and 5 to 16 years after cessation of monotherapy. Age of the children varied from 2 to 13 years. In two patients and in their children an inversion or a partial inversion of the heterochromatic region of chromosome 9 was observed.
Rokicka-Milewska
R
R
Derulska
D
D
Chmurzyńska-Mróz
E
E
D000328:Adult; D000970:Antineoplastic Agents / Q000633:toxicity; D002648:Child; D002675:Child, Preschool; D005260:Female; D005298:Fertility / Q000502:physiology*; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics* / Q000401:mortality; D012098:Reproduction / Q000502:physiology*
D000970:Antineoplastic Agents