Simultaneous spectrophotometric analysis of a ternary mixture of pharmaceuticals--assay for meclozine hydrochloride, pyridoxine hydrochloride and caffeine.
Based on an extension of Vierordt's method and in continuation of earlier work, the simultaneous analysis of a ternary mixture of meclozine hydrochloride, pyridoxine hydrochloride and caffeine is discussed. Using 0.01 M methanolic sodium hydroxide as the solvent, the absorbance of the solution of the mixture is recorded at 230, 273 and 307 nm. The concentration of each component is determined by the solution of three simultaneous equations.
Sharma
S C
SC
Central Indian Pharmacopoeia Laboratory, Raj Nagar, Ghaziabad.
Sharma
S C
SC
Saxena
R C
RC
Talwar
S K
SK
D002110:Caffeine / Q000032:analysis*; D004338:Drug Combinations; D007202:Indicators and Reagents; D008468:Meclizine / Q000032:analysis*; D011736:Pyridoxine / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet; D013607:Tablets
D004338:Drug Combinations; D007202:Indicators and Reagents; D013607:Tablets; D002110:Caffeine; D008468:Meclizine; D011736:Pyridoxine