title: Antileishmanial effect of free and encapsulated sinefungin against Leishmania donovani infections in BALB/c mice.
abstract: Sinefungin, a C-nucleoside antibiotic, displays a high antiparasitic action. The effect of free and microencapsulated sinefungin was compared on BALB/c mice infected with Leishmania donovani; the encapsulated form proved more effective by one order of magnitude.
authors.affiliation: London School of Hygiene and Tropical Medicine, Herts, Great Britain.
authors.forename: R A
authors.initials: RA
authors.lastname: Neal
authors.forename: M V
authors.initials: MV
authors.lastname: Iwobi
authors.forename: M
authors.initials: M
authors.lastname: Robert-Gero
mesh_terms: D000241:Adenosine / Q000031:analogs & derivatives; D000818:Animals; D000981:Antiprotozoal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002214:Capsules; D007893:Leishmania donovani; D007898:Leishmaniasis, Visceral / Q000188:drug therapy*; D051379:Mice; D008807:Mice, Inbred BALB C
chemical_list: D000981:Antiprotozoal Agents; D002214:Capsules; D000241:Adenosine; C006235:sinefungin