title: Double-blind evaluation of the effect of acute amantadine on cocaine craving.
abstract: Single doses of amantadine hydrochloride and placebo were administered in a double-blind cross-over design on separate days to ten actively craving cocaine abusers in treatment. Pharmacological treatment did influence cocaine craving, but amantadine was less effective than placebo.
authors.affiliation: Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519.
authors.forename: F H
authors.initials: FH
authors.lastname: Gawin
authors.forename: C
authors.initials: C
authors.lastname: Morgan
authors.forename: T R
authors.initials: TR
authors.lastname: Kosten
authors.forename: H D
authors.initials: HD
authors.lastname: Kleber
mesh_terms: D000547:Amantadine / Q000627:therapeutic use*; D003042:Cocaine / Q000494:pharmacology*; D004311:Double-Blind Method; D006801:Humans; D019966:Substance-Related Disorders / Q000188:drug therapy* / Q000523:psychology
chemical_list: D000547:Amantadine; D003042:Cocaine