title: Cloning, sequence analysis and chromosome localization of a Drosophila muscarinic acetylcholine receptor.
abstract: Two cDNA clones (3.7 kb and 4.8 kb) encoding a Drosophila muscarinic acetylcholine receptor were isolated from a Drosophila head cDNA library and characterized by automated DNA sequence analysis. The Drosophila muscarinic receptor contains 788 amino acids with a calculated Mr of 84,807 and displays greater than 60% homology with mammalian muscarinic receptors. The muscarinic receptor maps to the tip of the right arm of the second chromosome of the Drosophila genome.
authors.affiliation: Laboratory of Molecular and Cellular Neurobiology, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892.
authors.forename: T
authors.initials: T
authors.lastname: Onai
authors.forename: M G
authors.initials: MG
authors.lastname: FitzGerald
authors.forename: S
authors.initials: S
authors.lastname: Arakawa
authors.forename: J D
authors.initials: JD
authors.lastname: Gocayne
authors.forename: D A
authors.initials: DA
authors.lastname: Urquhart
authors.forename: L M
authors.initials: LM
authors.lastname: Hall
authors.forename: C M
authors.initials: CM
authors.lastname: Fraser
authors.forename: W R
authors.initials: WR
authors.lastname: McCombie
authors.forename: J C
authors.initials: JC
authors.lastname: Venter
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics; D004331:Drosophila melanogaster / Q000235:genetics*; D005796:Genes; D008969:Molecular Sequence Data; D011487:Protein Conformation; D011976:Receptors, Muscarinic / Q000235:genetics*; D015183:Restriction Mapping; D012689:Sequence Homology, Nucleic Acid; D012984:Software
chemical_list: D011976:Receptors, Muscarinic; D004247:DNA