title: Genetic localization of foraging (for): a major gene for larval behavior in Drosophila melanogaster.
abstract: Localizing genes for quantitative traits by conventional recombination mapping is a formidable challenge because environmental variation, minor genes, and genetic markers have modifying effects on continuously varying phenotypes. We describe "lethal tagging," a method used in conjunction with deficiency mapping for localizing major genes associated with quantitative traits. Rover/sitter is a naturally occurring larval foraging polymorphism in Drosophila melanogaster which has a polygenic pattern of inheritance comprised of a single major gene (foraging) and minor modifier genes. We have successfully localized the lethal tagged foraging (for, 2-10) gene by deficiency mapping to 24A3-C5 on the polytene chromosome map.
authors.affiliation: Department of Biology, York University, North York, Ontario, Canada.
authors.forename: J S
authors.initials: JS
authors.lastname: de Belle
authors.forename: A J
authors.initials: AJ
authors.lastname: Hilliker
authors.forename: M B
authors.initials: MB
authors.lastname: Sokolowski
mesh_terms: D000818:Animals; D001522:Behavior, Animal; D002874:Chromosome Mapping; D004331:Drosophila melanogaster / Q000235:genetics*; D005804:Genes, Lethal; D005819:Genetic Markers; D007814:Larva / Q000235:genetics*; D010641:Phenotype
chemical_list: D005819:Genetic Markers