title: The carbonic anhydrases: widening perspectives on their evolution, expression and function.
abstract: Now, some 55 years after its discovery in bovine red cells, carbonic anhydrase (CA), in all its varied forms, continues to challenge and intrigue physiologists, biochemists and molecular geneticists. This is so because of an increasing awareness of the many apparently diverse functions of the different CA isozymes encoded by this large multigene family, the continuing discovery of new CA, or CA-related, genes, and the extensive variation in their hormonal control, cellular expression and subcellular localization.
authors.forename: R E
authors.initials: RE
authors.lastname: Tashian
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D005075:Biological Evolution; D002256:Carbonic Anhydrases / Q000235:genetics* / Q000378:metabolism; D005796:Genes; D006801:Humans; D008969:Molecular Sequence Data; D011487:Protein Conformation; D012689:Sequence Homology, Nucleic Acid
chemical_list: D002256:Carbonic Anhydrases