title: [Morphometry and kinetics of jejunal epithelium in rats with niacin deficiency].
abstract: In niacin deficient rats, it was performed a kinetic and morphometric study of jejunal epithelium. It was observed that the deficient animals showed less villosity (515.1 mu x 570.1 mu; p less than 0.008), enterocyte (35.3 mu x 38.5 mu; p less than 0.004) and mitotic index (4.4% x 5.7%; p less than 0.001) and bigger crypt (238.0 mu x 186.1 mu; p less than 0.001) and cellular renovation time (22.9h x 17.8h; less than 0.001) according to control animals. It is suggested that NAD (nicotinamide-adenine dinucleotide) deficiency can be responsible for the observed alterations.
authors.affiliation: Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo.
authors.forename: C R
authors.initials: CR
authors.lastname: Victória
authors.forename: U G
authors.initials: UG
authors.lastname: Meneghelli
mesh_terms: D000818:Animals; D001835:Body Weight; D004032:Diet; D004848:Epithelium / Q000473:pathology; D007583:Jejunum / Q000473:pathology*; D008297:Male; D008867:Microtomy; D008940:Mitotic Index; D009525:Niacin / Q000172:deficiency*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D009525:Niacin
vernacular_title: Morfometria e cinética do epitélio jejunal em ratos com deficiência de niacina.