title: [The CREST syndrome associated with the sicca syndrome].
abstract: A case of CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal hypomotility, sclerodactyly, and telangiectasia) that initially showed Raynaud's phenomenon, sclerodactyly and polyarthralgias, 3 years later completing the process, associated to sicca syndrome, is presented. The esophageal affectation showed a loss of peristalsis of the inferior 2/3, as well as hypotonia of the gastroesophageal sphincter. We comment the prognostic relationship between CREST syndrome and the centromeric region antibodies.
authors.forename: J A
authors.initials: JA
authors.lastname: González Perez
authors.forename: J
authors.initials: J
authors.lastname: Calvo Catala
authors.forename: J V
authors.initials: JV
authors.lastname: Almela Requena
authors.forename: A
authors.initials: A
authors.lastname: González-Cruz Cervellera
authors.forename: E M
authors.initials: EM
authors.lastname: Sospedra Lara
authors.forename: M J
authors.initials: MJ
authors.lastname: Hurtado Vicente
mesh_terms: D000906:Antibodies / Q000032:analysis; D002114:Calcinosis / Q000175:diagnosis*; D002503:Centromere / Q000276:immunology; D004935:Esophageal Diseases / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011379:Prognosis; D011928:Raynaud Disease / Q000175:diagnosis*; D012595:Scleroderma, Systemic / Q000175:diagnosis*; D012859:Sjogren's Syndrome / Q000175:diagnosis*; D013577:Syndrome; D013684:Telangiectasis / Q000175:diagnosis*
chemical_list: D000906:Antibodies
vernacular_title: Síndrome de CREST asociado a síndrome seco.