title: [Behçet's disease: a study of 20 cases].
abstract: We observed 20 patients with ocular Behçet's disease. During the episodes of exacerbation the main features were: deep retinal infiltrates and vascular occlusions which were responsible for a sudden decrease in visual acuity. Also, there is posterior uveitis and retinal edema which persists during the whole course of the disease. In the final stages we observed an avascular, atrophic retina. Most patients also presented with a striking maculopathy and very often an atrophic optic disc was associated. On time of diagnosis, most patients were in their third decade, ranging from 19 to 61 years of age. Treatment consisted in administration of topical and systemic steroids. Most patients also required immunosuppressives and immunomodulators (cyclosporine A) in a later stage of the disease.
authors.forename: K
authors.initials: K
authors.lastname: Jacobs
authors.forename: J C
authors.initials: JC
authors.lastname: Vrijghem
authors.forename: C
authors.initials: C
authors.lastname: Linsen
authors.forename: A
authors.initials: A
authors.lastname: Leys
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000188:drug therapy / Q000503:physiopathology*; D003524:Cyclosporins / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D009896:Optic Atrophy / Q000503:physiopathology; D013256:Steroids / Q000008:administration & dosage; D014792:Visual Acuity
chemical_list: D003524:Cyclosporins; D007166:Immunosuppressive Agents; D013256:Steroids
vernacular_title: La maladie de Behçet: une étude de 20 cas.