[An analysis of the concentration-effect relation of glyceryl trinitrate in patients with stenocardia of effort after its single use in prolonged-release drug forms].
There is a correlation between the plasma concentrations of glycerol trinitrate and the antianginal effects of trinitrolong (application on the gingival mucosa) and nitroderm-TTS (application on the skin) in patients with angina pectoris by Hill's formula. The lower limit on the gingival mucosa) and nitroderm-TTS is 0.5-0.6 ng/ml.
Blagodatskikh
S V
SV
Piotrovskiĭ
V K
VK
Metelitsa
V I
VI
Martsevich
S Iu
SIu
Riabokon'
O S
OS
D000278:Administration, Buccal; D000279:Administration, Cutaneous; D000787:Angina Pectoris / Q000097:blood / Q000188:drug therapy*; D002908:Chronic Disease; D003692:Delayed-Action Preparations; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000008:administration & dosage* / Q000097:blood; D005082:Physical Exertion
D003692:Delayed-Action Preparations; D005996:Nitroglycerin
Analiz sviazi kontsentratsiia--éffekt trinitrata glitserina u bol'nykhstenokardieĭ napriazheniia posle odnokratnogo primeneniia v lekarstvennykh formakh s prolongirovannym vysvobozhdeniem.