Glossopharyngeal neuralgia with syncope and cervical mass.
GPN syndrome with syncope, hypotension, and bradycardia is rare. The association of this syndrome with neck masses mandates that these patients undergo a search for such tumors. A review of the literature and our experience revealed 12 cases of this syndrome associated with neck masses. The majority (60%) of the patients did not respond to medical therapy and eventually required a neurosurgical procedure to cure symptoms. However, medical therapy, including high-dose carbamazepine, should be tried first, particularly in individuals who represent a high operative risk.
Chalmers
A C
AC
Department of Internal Medicine, Naval Hospital, Oakland, CA 94627-5000.
Olson
J L
JL
D000368:Aged; D002220:Carbamazepine / Q000627:therapeutic use*; D005260:Female; D005930:Glossopharyngeal Nerve; D006801:Humans; D008297:Male; D008875:Middle Aged; D009437:Neuralgia / Q000188:drug therapy / Q000473:pathology*; D013575:Syncope / Q000188:drug therapy / Q000209:etiology; D014057:Tomography, X-Ray Computed
D002220:Carbamazepine