title: Single-electron-transfer in the reduction of 1,2-dioxetanes by biologically active substrates.
abstract: Substances of low oxidation potential, which can also make available protons and hydrogen atoms, e.g. phenothiazines, NADH, and ascorbic acid efficiently reduce 1,2-dioxetanes to their vic-diols by single-electron-transfer; a significant side reaction is catalytic decomposition of dioxetanes into the corresponding ketone fragments.
authors.affiliation: Institute of Organic Chemistry, University of Würzburg, F.R.G.
authors.forename: W
authors.initials: W
authors.lastname: Adam
authors.forename: F
authors.initials: F
authors.lastname: Vargas
authors.forename: B
authors.initials: B
authors.lastname: Epe
authors.forename: D
authors.initials: D
authors.lastname: Schiffmann
authors.forename: D
authors.initials: D
authors.lastname: Wild
mesh_terms: D001205:Ascorbic Acid; D055598:Chemical Phenomena; D002621:Chemistry; D002746:Chlorpromazine; D004579:Electron Transport; D006571:Heterocyclic Compounds; D009243:NAD; D010084:Oxidation-Reduction; D013329:Structure-Activity Relationship
chemical_list: D006571:Heterocyclic Compounds; D009243:NAD; D001205:Ascorbic Acid; D002746:Chlorpromazine