title: [Respiratory regulations of pulmonary vagal nerves under hypercapnic conditions; effects of J-receptor].
abstract: We studied ventilatory responses under hypercapnic condition in 9 lightly anesthetized dogs, using a vagal nerve cooling technique. One side of the cervical vagosympathetic trunks of dogs were previously severed, and a copper cooler was attached to the other side. When the cervical nerve was cooled below 7 degrees C, the Hering-Breuer inflation reflex ceased. We found that when the vagal nerve was not cooled or cooled to 7 degrees C, the respiratory frequency increased significantly in relation to hypercapnic gas inhalation. However, the increment of respiratory frequency was reduced by bilateral cervical vagotomy. We concluded that the J-receptor is responsible for the increase in respiratory frequency under hypercapnic gas inhalation.
authors.forename: Y
authors.initials: Y
authors.lastname: Sagara
authors.forename: K
authors.initials: K
authors.lastname: Isogami
authors.forename: H
authors.initials: H
authors.lastname: Saito
authors.forename: S
authors.initials: S
authors.lastname: Ono
authors.forename: T
authors.initials: T
authors.lastname: Sakuma
authors.forename: K
authors.initials: K
authors.lastname: Koike
authors.forename: T
authors.initials: T
authors.lastname: Nakata
mesh_terms: D000818:Animals; D002245:Carbon Dioxide / Q000502:physiology*; D004285:Dogs; D008168:Lung / Q000294:innervation*; D012018:Reflex; D012119:Respiration; D011984:Sensory Receptor Cells / Q000502:physiology*; D014630:Vagus Nerve / Q000502:physiology*
chemical_list: D002245:Carbon Dioxide