Studies on circulation rate and flow model for external loop bioreactor.
We performed experiments in an external loop bioreactor 250 mm in diameter and 4500 mm in height. The variation in circulation rate Um was studied over a wide range of surface gas velocities (UG = 0-24.9 cm/s), and a bioreactor flow model was obtained. We developed a new method (i.e., an electrical conductivity tracking system) to measure circulation rate and solve the problem of measuring general circulation resistance. A theoretical formula for Um was derived for use in scaling up the bioreactor: [formula: see text]
Liu
K
K
Beijing Research Institute for Nutritional Resources.
Jiang
X Z
XZ
Li
B Z
BZ
D001709:Biotechnology / Q000295:instrumentation*; D004553:Electric Conductivity; D007700:Kinetics; D008962:Models, Theoretical