[Clinical manifestations associated with the presence of lupus anticoagulant].
The case of a woman with systemic lupus erythematosus with unusual clinical, cutaneous and biologic features and lupus anticoagulant is presented. According to the literature this association is not fortuitous: a new syndrome characterized by the presence of a subgroup of antiphospholipid antibodies has been recognized. The cutaneous symptoms of this syndrome include: leg ulcers, livedo reticularis, widespread cutaneous necrosis and distal cutaneous ischemia. In our patient a nearly complete picture of the clinical and biologic features of this syndrome, including a characteristic retinal vein thrombosis is present.
Miori
L
L
Bellosta
M
M
Miori
E
E
Rabbiosi
G
G
D001327:Autoimmune Diseases / Q000473:pathology*; D001778:Blood Coagulation Disorders / Q000209:etiology; D001779:Blood Coagulation Factors / Q000276:immunology*; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000209:etiology; D016682:Lupus Coagulation Inhibitor; D008180:Lupus Erythematosus, Systemic / Q000276:immunology / Q000473:pathology*; D008875:Middle Aged; D010743:Phospholipids / Q000276:immunology*; D012170:Retinal Vein Occlusion / Q000209:etiology; D013577:Syndrome
D001779:Blood Coagulation Factors; D016682:Lupus Coagulation Inhibitor; D010743:Phospholipids
Manifestazioni cliniche associate alla presenza di anticoagulante lupico.