Aggregation of calcium ionophore (A23187) in phospholipid vesicles.
The circular dichroism studies on calcium ionophore, A23187, incorporated in Dipalmitoyl phosphatidyl choline (DPPC) vesicle showed interesting time dependent changes in the CD spectra. Analysis of the data indicated the possible aggregation of the observed dimeric structure of this molecule in non-polar solvents into a stacked dimeric pore in the phospholipid vesicle.
Balasubramanian
S V
SV
Molecular Biophysics Unit, Indian Institute of Science, Bangalore.
Easwaran
K R
KR
D015060:1,2-Dipalmitoylphosphatidylcholine; D000001:Calcimycin; D002942:Circular Dichroism; D007700:Kinetics; D008081:Liposomes; D046911:Macromolecular Substances; D015394:Molecular Structure
D008081:Liposomes; D046911:Macromolecular Substances; D015060:1,2-Dipalmitoylphosphatidylcholine; D000001:Calcimycin