[Studies on diamine oxidase (DAO) activity in seminal plasma].
Diamine oxidase (DAO: EC 1.4.3.6) activity was measured for seminal plasma of patients complaining of infertility to investigate whether measurement of DAO activity in seminal plasma is a significant laboratory examination or not for evaluation of male infertility. (1) DAO activity showed a slight decrease with increasing sperm density, but there was no significant correlation between DAO activity and sperm density. (2) DAO activity was higher in samples with sperm motility below 20%. There was a significant negative correlation between DAO activity and sperm motility. (3) DAO activity was higher in samples with motile sperm count below 10 x 10/ml. In conclusion, the simple spectrophotometric assays for DAO could form the base of a routine examination of male infertility.
Uchijima
Y
Y
Department of Urology, Saitama Medical Center, Saitama Medical School.
Yoshida
K
K
Kobayashi
N
N
Saitoh
H
H
D006631:Amine Oxidase (Copper-Containing) / Q000378:metabolism*; D004796:Clinical Enzyme Tests; D006801:Humans; D007248:Infertility, Male / Q000175:diagnosis; D008297:Male; D012661:Semen / Q000201:enzymology*; D013053:Spectrophotometry; D013076:Sperm Count; D013081:Sperm Motility
D006631:Amine Oxidase (Copper-Containing)