title: [Clinical manifestations associated with the presence of lupus anticoagulant].
abstract: The case of a woman with systemic lupus erythematosus with unusual clinical, cutaneous and biologic features and lupus anticoagulant is presented. According to the literature this association is not fortuitous: a new syndrome characterized by the presence of a subgroup of antiphospholipid antibodies has been recognized. The cutaneous symptoms of this syndrome include: leg ulcers, livedo reticularis, widespread cutaneous necrosis and distal cutaneous ischemia. In our patient a nearly complete picture of the clinical and biologic features of this syndrome, including a characteristic retinal vein thrombosis is present.
authors.forename: L
authors.initials: L
authors.lastname: Miori
authors.forename: M
authors.initials: M
authors.lastname: Bellosta
authors.forename: E
authors.initials: E
authors.lastname: Miori
authors.forename: G
authors.initials: G
authors.lastname: Rabbiosi
mesh_terms: D001327:Autoimmune Diseases / Q000473:pathology*; D001778:Blood Coagulation Disorders / Q000209:etiology; D001779:Blood Coagulation Factors / Q000276:immunology*; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000209:etiology; D016682:Lupus Coagulation Inhibitor; D008180:Lupus Erythematosus, Systemic / Q000276:immunology / Q000473:pathology*; D008875:Middle Aged; D010743:Phospholipids / Q000276:immunology*; D012170:Retinal Vein Occlusion / Q000209:etiology; D013577:Syndrome
chemical_list: D001779:Blood Coagulation Factors; D016682:Lupus Coagulation Inhibitor; D010743:Phospholipids
vernacular_title: Manifestazioni cliniche associate alla presenza di anticoagulante lupico.