Interferon-inducibility is diminished in tumour-bearing mice.
Inducibility of interferons was studied in tumour-bearing mice. Using five different transplantable tumour-models, diminishing of interferon-inducibility was revealed during tumour progression, irrespectively of the tumour-model used. Diminishing of interferon-inducibility runs parallel with development of the tumours.
Hung
P L
PL
Microbiological Research Group, National Institute of Hygiene, Budapest.
Stöger
I
I
Karczag
E
E
Minárovics
J
J
Földes
I
I
D000230:Adenocarcinoma / Q000188:drug therapy / Q000378:metabolism*; D000818:Animals; D005260:Female; D007372:Interferons / Q000096:biosynthesis* / Q000097:blood; D007941:Leukemia P388 / Q000188:drug therapy / Q000378:metabolism*; D007942:Leukemia, Experimental / Q000378:metabolism*; D008175:Lung Neoplasms / Q000188:drug therapy / Q000378:metabolism*; D008297:Male; D012515:Mast-Cell Sarcoma / Q000188:drug therapy / Q000378:metabolism*; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D011070:Poly I-C / Q000494:pharmacology
D007372:Interferons; D011070:Poly I-C