Identification of drug interactions by meta-analysis of premarketing trials: the effect of smoking on the pharmacokinetics and dosage requirements for flecainide acetate.
Holtzman
J L
JL
Medical Service, Veterans Affairs Medical Center, Minneapolis, MN 55417.
Weeks
C E
CE
Kvam
D C
DC
Berry
D A
DA
Mottonen
L
L
Ekholm
B P
BP
Chang
S F
SF
Conard
G J
GJ
D000293:Adolescent; D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D005260:Female; D005424:Flecainide / Q000008:administration & dosage / Q000493:pharmacokinetics*; D006331:Heart Diseases / Q000188:drug therapy*; D006801:Humans; D008297:Male; D015201:Meta-Analysis as Topic; D008875:Middle Aged; D012907:Smoking / Q000378:metabolism*
D005424:Flecainide