title: Human tissue response to porous hydroxyapatite implants. A case report.
abstract: Histological examination of 2 porous hydroxyapatite implants removed from a patient showed a pattern of ossification similar to that reported in a previous animal study. New bone was laid down on the surface of the hydroxyapatite but did not progress to occupy all the pores. Although porous hydroxyapatite blocks are biocompatible and well tolerated by the tissues, they are not recommended for augmentation of the resorbed alveolar ridge where the overlying mucosa is thin and atrophic, because of the risk of mucosal dehiscence and implant exposure. They are suitable in situations where they are deeply buried in the tissues and not subjected to direct trauma.
authors.affiliation: Department of Oral Surgery and Oral Medicine, Dental School St. Chad'sQueensway, Birmingham, UK.
authors.forename: J W
authors.initials: JW
authors.lastname: Frame
authors.forename: P G
authors.initials: PG
authors.lastname: Rout
authors.forename: R M
authors.initials: RM
authors.lastname: Browne
mesh_terms: D000540:Alveolar Ridge Augmentation; D001857:Bone Matrix / Q000033:anatomy & histology; D003094:Collagen; D005260:Female; D005347:Fibroblasts / Q000166:cytology; D006801:Humans; D006882:Hydroxyapatites; D008437:Maxilla / Q000033:anatomy & histology / Q000502:physiology*; D008875:Middle Aged; D010012:Osteogenesis; D019736:Prostheses and Implants; D013499:Surface Properties
chemical_list: D006882:Hydroxyapatites; D003094:Collagen