Recurrence of nephrocalcinosis after renal transplantation in an adult patient with primary hyperoxaluria type I.
The medical history of a 42-year-old patient with primary hyperoxaluria type I is presented. Primary hyperoxaluria was suspected after renal transplantation, when oxalate deposits were found in a biopsy of the kidney graft. Diagnosis of type I hyperoxaluria was confirmed by the finding that significantly increased amounts of glycolic acid and oxalic acid were excreted. Treatment of the patient with 500 mg pyridoxine daily resulted in a decrease of the excretion of oxalate to normal values.
Knols
G
G
Department of Internal Medicine, University Hospital, Maastricht, The Netherlands.
Leunissen
K M
KM
Spaapen
L J
LJ
Bosman
F T
FT
vd Wiel
T W
TW
Kootstra
G
G
van Hooff
J P
JP
D000328:Adult; D005260:Female; D006085:Graft Survival; D006801:Humans; D006959:Hyperoxaluria / Q000150:complications*; D006960:Hyperoxaluria, Primary / Q000150:complications* / Q000473:pathology; D007668:Kidney / Q000473:pathology; D016030:Kidney Transplantation; D007684:Kidney Tubules / Q000473:pathology; D009397:Nephrocalcinosis / Q000209:etiology* / Q000473:pathology; D012008:Recurrence