Common bile-duct mucosa in choledochoduodenostomy patients--histological and histochemical study.
We describe the histological and histochemical changes of the common bile-duct mucosa in specimens obtained by means of peroral cholangioscopy, 1-12 years after choledochoduodenal anastomosis. Our findings--hyperplasia of the superficial epithelium, metaplastic goblet cells containing predominantly acid sialomucins, and pyloric-like gland formation containing neutral mucins--express a morphological and functional differentiation of the common bile-duct mucosa that probably facilitates its survival in a different environment. We consider that these adaptive changes may explain the uneventful long-term postoperative period of choledochoduodenostomized patients.
Eleftheriadis
E
E
Department of Surgery, University of Thessaloniki, Greece.
Tzioufa
V
V
Kotzampassi
K
K
Aletras
H
H
D002768:Choledochostomy; D003135:Common Bile Duct / Q000737:chemistry / Q000473:pathology*; D004848:Epithelium / Q000473:pathology; D006801:Humans; D009077:Mucins / Q000737:chemistry; D009092:Mucous Membrane / Q000737:chemistry / Q000473:pathology; D052116:Sialomucins; D013194:Staining and Labeling
D009077:Mucins; D052116:Sialomucins