title: The epidemiology of HIV transmission among paid plasma donors, Mexico City, Mexico.
abstract: Screening of blood product donations for antibody to HIV began in Mexico in May 1986. From June to October 1986, the HIV cumulative seroprevalence increased from 6.3 to 9.2% in a commercial plasma collection center. Of the 281 people who donated the antibody-positive units, 62 (22.1%) had documented seroconversion during these 5 months. An epidemiologic study of 54 seropositive and 58 seronegative donors was carried out. The HIV serologic status did not change in any of these donors after repeat testing. Only 13.0% of the seropositives and 15.5% of the seronegatives had any of the known risk factors for AIDS. There was a direct relationship between frequency of plasma donation and the risk of being seropositive. A survey of employees disclosed the frequent re-use of disposable blood collection equipment. We conclude that HIV transmission had probably occurred in this plasma collection center.
authors.affiliation: Directorate of Epidemiology, Secretariat of Health, Mexico.
authors.forename: C
authors.initials: C
authors.lastname: Avila
authors.forename: H C
authors.initials: HC
authors.lastname: Stetler
authors.forename: J
authors.initials: J
authors.lastname: Sepúlveda
authors.forename: E
authors.initials: E
authors.lastname: Dickinson
authors.forename: K G
authors.initials: KG
authors.lastname: Castro
authors.forename: J W
authors.initials: JW
authors.lastname: Ward
authors.forename: G
authors.initials: G
authors.lastname: Romero
authors.forename: J L
authors.initials: JL
authors.lastname: Valdespino
mesh_terms: D000328:Adult; D001771:Blood Banks / Q000191:economics / Q000592:standards*; D001782:Blood Donors; D001815:Bloodletting / Q000295:instrumentation; D003264:Containment of Biohazards / Q000592:standards*; D004866:Equipment Contamination; D005260:Female; D006679:HIV Seropositivity / Q000453:epidemiology*; D015528:HIV Seroprevalence; D006801:Humans; D007757:Laboratory Infection / Q000209:etiology; D008297:Male; D008800:Mexico / Q000453:epidemiology; D010956:Plasmapheresis / Q000295:instrumentation; D012307:Risk Factors; D012959:Socioeconomic Factors; D014505:Urban Population