title: Episodic secretion of inhibin into the ovarian vein during the follicular phase of the oestrous cycle in the ewe.
abstract: Changes in the plasma concentration of inhibin were measured by radioimmunoassay in ovarian venous blood collected at 10-min intervals for 5-h periods between 16 and 21 h and 40 and 45 h after cloprostenol-induced luteal regression in six Finn-Merino sheep. Episodes of inhibin secretion occurred with an interpulse interval of 66 +/- 5 min in both stages of the follicular phase. These changes in inhibin were unrelated to pulses of LH or oestradiol. There was no relationship with plasma concentrations of FSH, which did not change in a pulsatile manner. These results suggest that the release of inhibin by the preovulatory follicle(s) occurs in a pulsatile manner and is under local control by unknown factors.
authors.affiliation: MRC Reproductive Biology Unit, University of Edinburgh.
authors.forename: A S
authors.initials: AS
authors.lastname: McNeilly
authors.forename: D T
authors.initials: DT
authors.lastname: Baird
mesh_terms: D000818:Animals; D004958:Estradiol / Q000097:blood; D004971:Estrus / Q000097:blood*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D005498:Follicular Phase; D007265:Inhibins / Q000097:blood*; D007986:Luteinizing Hormone / Q000097:blood; D010053:Ovary / Q000098:blood supply*; D011673:Pulsatile Flow; D012212:Rheology; D012756:Sheep / Q000097:blood*; D014680:Veins / Q000378:metabolism
chemical_list: D004958:Estradiol; D007265:Inhibins; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone