title: Benzoic acid metabolism in presence of Schistosoma mansoni infection in mice.
abstract: The metabolism of benzoic acid was examined in S. mansoni infected CBA mouse. The result showed that control animals dosed with 150 mg/kg benzoic acid resulted in urinary excretion of two metabolites, hippuric acid and benzoic acid glucuronide. Administration of the same dose to animal carrying S. mansoni for a period of over 6 weeks resulted in decreased formation of hippuric acid and total elimination of benzoic acid by glucuronide pathway.
authors.forename: T S
authors.initials: TS
authors.lastname: Emundianughe
mesh_terms: D000217:Acyltransferases / Q000652:urine; D000818:Animals; D001565:Benzoates / Q000378:metabolism*; D019817:Benzoic Acid; D014453:Glucuronosyltransferase / Q000652:urine; D006626:Hippurates / Q000652:urine; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D012555:Schistosomiasis mansoni / Q000378:metabolism*
chemical_list: D001565:Benzoates; D006626:Hippurates; D019817:Benzoic Acid; D000217:Acyltransferases; C020680:glycine acyltransferase; D014453:Glucuronosyltransferase