title: CT-guided pancreatic percutaneous fine-needle biopsy in differential diagnosis between pancreatic cancer and chronic pancreatitis.
abstract: Differential diagnosis between pancreatic cancer and chronic pancreatitis is still difficult to establish. In 63 patients with suspected pancreatic neoplasm we performed: serum CA 19-9 assessment, abdominal ultrasound. CT scan and CT-guided pancreatic percutaneous fine-needle biopsy. The conclusive diagnosis was pancreatic cancer in 40 patients and chronic pancreatitis in 23 patients. With regard to the differential diagnosis, sensitivity and specificity were respectively 80% and 78% for serum CA 19-9, 75% and 65% for abdominal US. 85% and 70% for CT scan. 00% and 87% for percutaneous fine-needle biopsy. We conclude that CT-guided percutaneous fine-needle biopsy is the most reliable method for differential diagnosis between pancreatic cancer and chronic pancreatitis.
authors.affiliation: Cattedre di Patologia Speciale Chirurgica, Istituto Scientifico H.S. Raffaele, Università di Milano, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Carlucci
authors.forename: A
authors.initials: A
authors.lastname: Zerbi
authors.forename: D
authors.initials: D
authors.lastname: Parolini
authors.forename: S
authors.initials: S
authors.lastname: Sironi
authors.forename: A
authors.initials: A
authors.lastname: Vanzulli
authors.forename: C
authors.initials: C
authors.lastname: Staudacher
authors.forename: A
authors.initials: A
authors.lastname: Faravelli
authors.forename: P
authors.initials: P
authors.lastname: Garancini
authors.forename: A
authors.initials: A
authors.lastname: Del Maschio
authors.forename: V
authors.initials: V
authors.lastname: Di Carlo
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis; D001707:Biopsy, Needle; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology*; D010195:Pancreatitis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology*; D011237:Predictive Value of Tests; D014057:Tomography, X-Ray Computed
chemical_list: D015295:Antigens, Tumor-Associated, Carbohydrate