title: [Pre-existing diseases as risk factors and prognosis of genito-urinary infection in pregnancy].
abstract: With the intention of reducing the abortion, preterm delivery and perinatal mortality caused by the genito urinary infection (GUI) we attempt to identify the risk factors and with those make a diagnostic test, that permits detection and prediction of GUI during gestation period. Morbidity records that suggests alterations of immune response were studied in a group of 165 pregnant women that presented GUI and were compared with 86 pregnant women without GUI. As risk antecedents, we found: spontaneous abortions of second trimester 42.4% (study group) and 6.9% (control group) (p < 0.01), repeated vaginitis 31.5% and 2.3% (p < 0.01) urinary tract infection (UTI) 29.7% and 6.92% (p < 0.01), preterm deliveries 17.6% and 3.52% (p < 0.01), puerperal infection 9.12% and 0.0% (p < 0.05), familiar diabetes 21.2% and 8.12% (p < 0.05). Psychiatric pathology 12.72 and 3.5% (p < 0.05), typhoid fever 12.1% and 3.5% (p < 0.05) and surgical infections 16.4% and 8.12% (p < 0.1). A score was elaborated assigning 1/2 point to: puerperal infections, familiar diabetes, psychiatric pathology, typhoid fever and surgical infections; 1 point to: abortion, vaginitis, UTI and preterm delivery and 2 points to: repeated abortion, UTI and preterm delivery. Patients were divided in multiparous and primiparas. In multiparous with 1 or more points we found: sensitivity 75.3%, specificity 81%, positive predictive value 89.3%, negative predictive value 60.7% and accuracy 77.1%. In primiparas with 1/2 or more points we found: sensitivity 61.8%, specificity 70.5%, positive predictive value 78.3%, negative predictive value 51.7% and accuracy 65%.
authors.affiliation: Servicio de Obstetricia y Ginecología, Hospital Paula Jaraquemada.
authors.forename: A
authors.initials: A
authors.lastname: Ovalle
authors.forename: O
authors.initials: O
authors.lastname: Silva
authors.forename: R
authors.initials: R
authors.lastname: Herrera
authors.forename: E
authors.initials: E
authors.lastname: González
authors.forename: J
authors.initials: J
authors.lastname: Marín
mesh_terms: D000022:Abortion, Spontaneous / Q000517:prevention & control; D002677:Chile; D005260:Female; D052776:Female Urogenital Diseases / Q000150:complications*; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D007752:Obstetric Labor, Premature / Q000517:prevention & control; D010298:Parity; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology*; D011379:Prognosis; D012307:Risk Factors; D014552:Urinary Tract Infections / Q000150:complications*
vernacular_title: Antecedentes mórbidos de riesgo y predicción de la infección génito-urinaria durante el embarazo.