[The influence of fat emulsions in ternary mixing during total parenteral feeding on biological and galenic parameters].
Visual and microscopic inspection, pH, osmolality, measurements of particle size were made on one formulation of parenteral admixture. Based on examination of particle size distribution, admixtures prepared from Intrapilide or Ivelip were stable for up to four days. The results of visual and microscopic inspection in case of using Endolipide concluded to a shorter stability in that case. In the second part of this work the two fat emulsions Intralipide and Ivelip were studied to blow out any clinical or biochemical differences between two groups of patients. This clinical study was carried on fourty two patients recovering from digestive surgery. Patient metabolic parameters such as albumin and prealbumin remained the same in the two groups. The serum alkaline phosphatase has significantly been increasing in group Ivelip. Serum phosphoremia has been increasing in group Intralipide.
Sarocchi
C
C
Choux
C
C
Thillard
J G
JG
Seguier
J C
JC
Brossard
D
D
D002626:Chemistry, Pharmaceutical; D004066:Digestive System Diseases / Q000601:surgery; D004339:Drug Compounding; D005217:Fat Emulsions, Intravenous / Q000378:metabolism / Q000494:pharmacology; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D009994:Osmolar Concentration; D010289:Parenteral Nutrition, Total; D010316:Particle Size; D013997:Time Factors
D005217:Fat Emulsions, Intravenous
Influence de l'émulsion lipidique en mélange ternaire lors de la nutrition parenterale totale sur les paramètres galéniques et biologiques.