Effect of weight loss on thiazide produced erectile problems in men.
Thiazide-type diuretics frequently produce erectile dysfunction in men on a regular diet. However, men on a weight-loss diet have much less erectile dysfunction. Thiazide-type diuretics also produce erectile dysfunction in rats and interfere with normal copulation. The mechanism of the dysfunction and the favorable response to weight loss is unknown.
Langford
H G
HG
Department of Medicine, University of Mississippi Medical Center, Jackson.
Rockhold
R W
RW
Wassertheil-Smoller
S
S
Oberman
A
A
Davis
B R
BR
Blaufox
M D
MD
D000818:Animals; D001581:Benzothiadiazines; D004232:Diuretics; D004353:Drug Evaluation, Preclinical; D006801:Humans; D006973:Hypertension / Q000178:diet therapy / Q000188:drug therapy; D007989:Libido / Q000187:drug effects; D008297:Male; D010410:Penile Erection / Q000187:drug effects*; D051381:Rats; D012735:Sexual Dysfunction, Physiological / Q000139:chemically induced / Q000517:prevention & control; D049993:Sodium Chloride Symporter Inhibitors / Q000009:adverse effects*; D015431:Weight Loss
D001581:Benzothiadiazines; D004232:Diuretics; D049993:Sodium Chloride Symporter Inhibitors