Value of Humphrey perimetry in the detection of early chloroquine retinopathy.
Various forms of perimetry are used to confirm Chloroquine retinopathy diagnosed by Amsler grid testing. Little is known about the value of using a red target generated statically. The purpose of this study was to determine the sensitivity and specificity of both red and white perimetry using program 10-2 on the Humphrey automated perimeter. Sixty-nine eyes were tested in total. Fifty eyes were from patients with known early Chloroquine retinopathy with abnormal Amslers. Red perimetry was 91.3% sensitive and 57.8% specific for Chloroquine retinopathy. White perimetry was 78% sensitive and 84% specific for this condition. In conclusion, red Humphrey perimetry was highly sensitive but not highly specific for Chloroquine retinopathy.
Easterbrook
M
M
Department of Ophthalmology, University of Toronto, Ontario.
Trope
G
G
D000368:Aged; D002738:Chloroquine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D011379:Prognosis; D012164:Retinal Diseases / Q000139:chemically induced / Q000175:diagnosis*; D012680:Sensitivity and Specificity; D058609:Visual Field Tests / Q000379:methods*; D014794:Visual Fields / Q000187:drug effects
D002738:Chloroquine