Hydrops fetalis due to homozygosity for alpha-thalassemia-1, -(alpha)-20.5 kb: the first observation in a Turkish family.
We report data on a fetus with hydrops fetalis due to a homozygosity for alpha-thalassemia-1, type -(alpha)-20.5 kb; this is the first reported case in a Turkish family. Characterization of the abnormality was based on data from family studies and from alpha-globin gene mapping of the DNA from the parents.
Gurgey
A
A
Department of Pediatrics, Hacettepe University, Ankara, Turkey.
Altay
C
C
Beksaç
M S
MS
Bhattacharya
R
R
Kutlar
F
F
Huisman
T H
TH
D000328:Adult; D004247:DNA / Q000097:blood / Q000235:genetics; D005260:Female; D005313:Fetal Death / Q000097:blood / Q000235:genetics; D005914:Globins / Q000032:analysis / Q000235:genetics; D006455:Hemoglobins, Abnormal / Q000032:analysis / Q000235:genetics*; D006720:Homozygote; D006801:Humans; D015160:Hydrops Fetalis / Q000097:blood / Q000235:genetics*; D011247:Pregnancy; D013789:Thalassemia / Q000097:blood / Q000235:genetics*; D014421:Turkey
D006455:Hemoglobins, Abnormal; D005914:Globins; D004247:DNA; C030448:hemoglobin Bart's