title: Primary intracranial CNS lymphoma: MR manifestations.
abstract: We reviewed MR scans of 10 patients with biopsy-proved primary CNS lymphoma. Twenty-five lesions were identified in 10 patients (four with AIDS and six without AIDS). In general, the typical lesion of CNS lymphoma was found to have the following MR characteristics: they were slightly hypointense on T1-weighted images and slightly hyperintense on proton density and T2-weighted images relative to gray matter; they induced mild edema and mild to moderate mass effect. In AIDS patients, 82% of the lesions were smaller than 2 cm in diameter, and were frequently located in the temporal lobes and basal ganglia; they were often multiple. In non-AIDS patients, 75% of the lesions were larger than 2 cm in diameter and were primarily found in the deep parietal lobe; most were solitary.
authors.affiliation: Department of Radiology, University of California, San Diego 92103-1990.
authors.forename: B W
authors.initials: BW
authors.lastname: Schwaighofer
authors.forename: J R
authors.initials: JR
authors.lastname: Hesselink
authors.forename: G A
authors.initials: GA
authors.lastname: Press
authors.forename: R L
authors.initials: RL
authors.lastname: Wolf
authors.forename: M E
authors.initials: ME
authors.lastname: Healy
authors.forename: D P
authors.initials: DP
authors.lastname: Berthoty
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000175:diagnosis; D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000175:diagnosis*; D002493:Central Nervous System Diseases / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged