title: Amount, avidity, and specificity of antibodies to Pseudomonas aeruginosa in normal human sera.
abstract: Seventy-two normal human sera from healthy blood donors were tested by an enzyme-linked immunosorbent assay in order to determine the amounts and avidities of immunoglobulins M and G antibodies to lipopolysaccharides of seven Fisher's immunotypes of Pseudomonas aeruginosa and to exotoxin A. The patterns of specificity for seven immunotypes in all individual sera were determined. These data show a predominance of antibodies directed to Fisher's immunotypes 7 and 4 in the human population tested and may reflect frequency of occurrence of immunotypes outside the hospital environment.
authors.affiliation: Department of Microbiology, Military Institute of Hygiene and Epidemiology, Warsaw, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Grzybowski
authors.forename: E A
authors.initials: EA
authors.lastname: Trafny
authors.forename: J
authors.initials: J
authors.lastname: Wrembel-Wargocka
authors.forename: J
authors.initials: J
authors.lastname: Patzer
authors.forename: D
authors.initials: D
authors.lastname: Dzierzanowska
authors.forename: I
authors.initials: I
authors.lastname: Zawistowska-Marciniak
authors.forename: M
authors.initials: M
authors.lastname: Kłos
mesh_terms: D036002:ADP Ribose Transferases; D000907:Antibodies, Bacterial / Q000032:analysis* / Q000276:immunology; D000918:Antibody Specificity; D000942:Antigens, Bacterial / Q000276:immunology*; D001427:Bacterial Toxins; D001782:Blood Donors; D004797:Enzyme-Linked Immunosorbent Assay; D005098:Exotoxins / Q000276:immunology; D006801:Humans; D007106:Immune Sera / Q000276:immunology; D007074:Immunoglobulin G / Q000032:analysis / Q000276:immunology; D007075:Immunoglobulin M / Q000032:analysis / Q000276:immunology; D008070:Lipopolysaccharides / Q000276:immunology; D011550:Pseudomonas aeruginosa / Q000276:immunology*; D037521:Virulence Factors; D000097668:Pseudomonas aeruginosa Exotoxin A
chemical_list: D036002:ADP Ribose Transferases; D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D001427:Bacterial Toxins; D005098:Exotoxins; D007106:Immune Sera; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008070:Lipopolysaccharides; D037521:Virulence Factors; D000097668:Pseudomonas aeruginosa Exotoxin A