title: Proposed protocol for the evaluation of the effect of high purity factor concentrates on the immune system of hemophilia patients.
authors.affiliation: New England Area Comprehensive Hemophilia Center, Worcester, MA.
authors.forename: D B
authors.initials: DB
authors.lastname: Brettler
mesh_terms: D015704:CD4 Antigens / Q000378:metabolism; D002985:Clinical Protocols; D002986:Clinical Trials as Topic / Q000379:methods; D005169:Factor VIII / Q000008:administration & dosage* / Q000009:adverse effects; D006679:HIV Seropositivity / Q000150:complications; D006467:Hemophilia A / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D007107:Immune System / Q000187:drug effects*; D015337:Multicenter Studies as Topic; D011446:Prospective Studies
chemical_list: D015704:CD4 Antigens; D005169:Factor VIII