Anabolic steroid therapies for growth disorders.
Until recently, human growth hormone was the only endocrine therapy available for promotion of growth and development. Dramatic progress in understanding the secretory and regulatory pathways pertinent to the anabolic steroids has led to multiple pharmacologic approaches. Growth hormone dynamics and its impact on therapy are discussed.
Rogol
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AD
University of Virginia School of Medicine, Charlottesville.
D045930:Anabolic Agents / Q000627:therapeutic use*; D000818:Animals; D001846:Bone Development / Q000187:drug effects; D006130:Growth Disorders / Q000188:drug therapy*; D013006:Growth Hormone / Q000009:adverse effects / Q000097:blood / Q000502:physiology*; D013007:Growth Hormone-Releasing Hormone / Q000502:physiology*; D006801:Humans; D007031:Hypothalamus / Q000187:drug effects; D007334:Insulin-Like Growth Factor I / Q000009:adverse effects / Q000502:physiology* / Q000627:therapeutic use; D051379:Mice; D010902:Pituitary Gland / Q000187:drug effects; D011994:Recombinant Proteins / Q000627:therapeutic use; D013002:Somatomedins / Q000502:physiology*
D045930:Anabolic Agents; D011994:Recombinant Proteins; D013002:Somatomedins; D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone; D013007:Growth Hormone-Releasing Hormone