title: Ciprofloxacin in combination with other antimicrobials.
abstract: Combinations of ciprofloxacin with aminoglycosides or beta-lactams are infrequently synergistic and only rarely antagonistic against Enterobacteriaceae or gram-positive bacteria. Against Pseudomonas aeruginosa, combinations of ciprofloxacin with an aminoglycoside are synergistic for a minority of isolates, whereas rates of synergistic interactions between ciprofloxacin and beta-lactams against this group of organisms vary over a wide range.
authors.affiliation: Department of Medicine, New England Deaconess Hospital, Boston, Massachusetts 02215.
authors.forename: G M
authors.initials: GM
authors.lastname: Eliopoulos
authors.forename: C T
authors.initials: CT
authors.lastname: Eliopoulos
mesh_terms: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002939:Ciprofloxacin / Q000494:pharmacology*; D004357:Drug Synergism; D004359:Drug Therapy, Combination / Q000494:pharmacology*; D004755:Enterobacteriaceae / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D007769:Lactams; D008826:Microbial Sensitivity Tests; D011550:Pseudomonas aeruginosa / Q000187:drug effects
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D007769:Lactams; D002939:Ciprofloxacin