title: Cardiovascular effects of leukotrienes.
abstract: Leukotrienes have been shown to significantly influence coronary vascular resistance, infarct size, pulmonary vascular resistance, bronchial tone, and renal vascular resistance either directly or indirectly. There is a notable dearth of data on human pathophysiologic conditions. With the advent of specific inhibitors of the synthesis and action of leukotrienes and, more importantly, of methods on the in-vivo synthesis of these potentially important mediators, these gaps in our understanding will be closed.
authors.affiliation: Department of Clinical Pharmacology, Hannover Medical School, West Germany.
authors.forename: J
authors.initials: J
authors.lastname: Fauler
authors.forename: J C
authors.initials: JC
authors.lastname: Frölich
mesh_terms: D000818:Animals; D002319:Cardiovascular System / Q000187:drug effects*; D006801:Humans; D015289:Leukotrienes / Q000494:pharmacology*
chemical_list: D015289:Leukotrienes