title: In situ hybridization localizes the human putative oncogene GLI to chromosome subbands 12q13.3-14.1.
abstract: Using in situ hybridization, we have localized the human putative oncogene GLI to chromosome subbands 12q13.3-14.1. The precise genomic site is of interest since the region 12q13-15 has been found to be consistently rearranged in neoplasia-associated chromosome abnormalities in lipomas, myxoid liposarcomas, uterine leiomyomas, and pleomorphic adenomas of the salivary gland.
authors.affiliation: Department of Clinical Genetics, University Hospital, Lund, Sweden.
authors.forename: K
authors.initials: K
authors.lastname: Arheden
authors.forename: M
authors.initials: M
authors.lastname: Rønne
authors.forename: N
authors.initials: N
authors.lastname: Mandahl
authors.forename: S
authors.initials: S
authors.lastname: Heim
authors.forename: K W
authors.initials: KW
authors.lastname: Kinzler
authors.forename: B
authors.initials: B
authors.lastname: Vogelstein
authors.forename: F
authors.initials: F
authors.lastname: Mitelman
mesh_terms: D002871:Chromosome Banding; D002881:Chromosomes, Human, Pair 12; D004273:DNA, Neoplasm / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics*; D006801:Humans; D008667:Metalloproteins / Q000235:genetics*; D009369:Neoplasms / Q000235:genetics; D009693:Nucleic Acid Hybridization; D009857:Oncogenes; D014178:Translocation, Genetic
chemical_list: D004273:DNA, Neoplasm; D004268:DNA-Binding Proteins; D008667:Metalloproteins