In vitro inhibition of brain glutamic acid decarboxylase by sodium 2-mercaptoethanesulphonate and endogenous thiols and its possible in vivo consequences.
Shaw
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IC
Toxicology Laboratory, University College London, UK.
Aas
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P
D000818:Animals; D001812:Blood-Brain Barrier / Q000187:drug effects; D001921:Brain / Q000201:enzymology*; D003545:Cysteine / Q000494:pharmacology; D005968:Glutamate Decarboxylase / Q000037:antagonists & inhibitors*; D005978:Glutathione / Q000494:pharmacology; D066298:In Vitro Techniques; D008297:Male; D008623:Mercaptoethanol / Q000031:analogs & derivatives*; D015080:Mesna / Q000493:pharmacokinetics / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D013438:Sulfhydryl Compounds / Q000494:pharmacology*
D013438:Sulfhydryl Compounds; D008623:Mercaptoethanol; D005968:Glutamate Decarboxylase; D005978:Glutathione; D003545:Cysteine; D015080:Mesna