title: Spontaneous recovery from hypopituitarism due to postpartum hemorrhage.
abstract: A rare case is presented of a woman with spontaneous recovery from hypopituitarism following postpartum hemorrhage. One month after delivery, serum thyroid hormone, TSH, LH and FSH levels were low, and their secretion from the pituitary gland responded poorly to the TRH and LH-RH tests. Pituitary TSH response was normal 3 months after delivery. In the LH-RH test, pituitary LH and FSH response returned to normal at 2 months. Pituitary GH secretion and serum cortisol levels induced by ITT already responded normally one month postpartum. Excessive secretion of pituitary PRL was observed 3 months after delivery and improved gradually thereafter. These results indicate that the secretion of pituitary tropic hormones was sensitive to pituitary ischemia in the following order: TSH, gonadotropin, GH and ACTH. The disturbance of these hormones also persisted in the same order.
authors.affiliation: Department of Internal Medicine, Fujita-Gakuen Health University School of Medicine, Aichi, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ohyama
authors.forename: A
authors.initials: A
authors.lastname: Nagasaka
authors.forename: A
authors.initials: A
authors.lastname: Nakai
authors.forename: T
authors.initials: T
authors.lastname: Aono
authors.forename: R
authors.initials: R
authors.lastname: Masunaga
authors.forename: K
authors.initials: K
authors.lastname: Kataoka
authors.forename: H
authors.initials: H
authors.lastname: Nakagawa
authors.forename: S
authors.initials: S
authors.lastname: Kato
authors.forename: T
authors.initials: T
authors.lastname: Kawabe
authors.forename: H
authors.initials: H
authors.lastname: Majima
mesh_terms: D000328:Adult; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007018:Hypopituitarism / Q000209:etiology*; D007986:Luteinizing Hormone / Q000097:blood; D010908:Pituitary Hormones, Anterior / Q000097:blood; D006473:Postpartum Hemorrhage / Q000150:complications*; D011247:Pregnancy; D012075:Remission, Spontaneous; D013972:Thyrotropin / Q000097:blood
chemical_list: D010908:Pituitary Hormones, Anterior; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin; D006854:Hydrocortisone