[Increase in body weight and levels of organochlorine insecticide and polychlorinated biphenyl residues in the blood during pregnancy].
Concentrations of organochlorine residues, viz., p,p'DDE, p,p'DDT, total DDT, gamma-HCH and polychlorinated biphenyl (PHB) were determined in the serum of both pregnant and unpregnant women. It appeared that concentrations of these residues were statistically significantly lower in the pregnant women. Besides, some variations in these concentrations, observed at three stages of pregnancy (the third month, the sixth month and at the delivery), were not statistically significant. With the body weight increase during the pregnancy, an increase, instead of the expected decrease, in concentration of organochlorine residues was observed. The increase in organochlorine residue content which is statistically significant may be of clinical significance. Those pregnant women that had a greater body mass increase had also higher concentrations of organochlorine contaminants in the serum. This means that the fetus was exposed more strongly to their action. An explanation of this phenomenon should be sought in the numerous physiological changes occurring in the pregnancy. In is necessary to continue the study of the correlation between the body mass increase and the concentration of organochlorine residues in the serum of pregnant women and their milk after the delivery.
Roncević
N
N
Pavkov
S
S
Galetin-Smith
R
R
Vojinović
M
M
Dordević
M
M
D005260:Female; D006801:Humans; D007306:Insecticides / Q000097:blood*; D010573:Pesticide Residues / Q000097:blood; D011078:Polychlorinated Biphenyls / Q000097:blood*; D011247:Pregnancy / Q000097:blood*; D000091402:Prohibitins; D015430:Weight Gain
D007306:Insecticides; C000717328:PHB protein, human; D010573:Pesticide Residues; D000091402:Prohibitins; D011078:Polychlorinated Biphenyls
Prirast telesne mase i koncentracije rezidua organohlornih insekticida i polihlorovanih bifenila u serumu trudnica.