[Treatment of patients with food allergy using Nalcrom].
A total of 65 patients with food allergy which manifested primarily by disorders of the gastrointestinal tract, bronchi and skin were placed under observation. The patients were administered sodium chromoglycate (nalcrom) per os in a dose of 200 mg 4 times a day for 2-3 weeks, in part of cases up to 3 months and even up to 1-1.5 year. The skin manifestations of allergy (pruritus, urticaria, Quincke's edema, and eczematous rash), abdominal pain, diarrhea, vomiting, bronchospasm, rhinitis, and conjunctivitis disappeared. At the same time the majority of the patients demonstrated the reduction of the intensity of skin responses to the administration of different food antigens, the decrease of the antibody titer in blood serum in response to food antigens, and of the IgE content in blood. The side effects (nausea, heartburn, intensification of skin itch and abdominal pain) were noted in 4 cases.
Nogaller
A M
AM
Orlov
V A
VA
Luniakov
A S
AS
Motuzka
N P
NP
Petukhova
V K
VK
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D004205:Cromolyn Sodium / Q000008:administration & dosage*; D003876:Dermatitis, Atopic / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005512:Food Hypersensitivity / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011537:Pruritus; D014581:Urticaria / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology
D004205:Cromolyn Sodium
Lechenie bol'nykh pishchevoĭ allergieĭ s primeneniem nalkroma.