title: Ultrastructural localization of carbonic anhydrase in the vestibular end organs of the guinea pig.
abstract: Carbonic anhydrase activity was demonstrated cytochemically on an ultrastructural level in the vestibular end organs of the guinea pig. Reaction product was found in the dark cells, transitional cells, cells of the planum semilunatum and supporting cells. In the dark cells, reaction product was observed in the cytoplasm as well as in the basal infoldings. Reaction product was also observed in the basal infoldings of the transitional cells and the cells of the planum semilunatum. The globular structures inside the supporting cells, transitional cells and the cells of the planum semilunatum were also surrounded by the reaction product. These findings suggest that carbonic anhydrase may have different functions, such as water and ion transport, respiration, nutrition and calcium carbonate deposition in the vestibular end organs.
authors.affiliation: Department of Otolaryngology, Karolinska Sjukhuset, Karolinska Institutet, Stockholm, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: Takumida
authors.forename: D
authors.initials: D
authors.lastname: Bagger-Sjöbäck
authors.forename: J
authors.initials: J
authors.lastname: Wersäll
authors.forename: Y
authors.initials: Y
authors.lastname: Harada
mesh_terms: D000818:Animals; D002256:Carbonic Anhydrases / Q000378:metabolism*; D006168:Guinea Pigs; D009411:Nerve Endings / Q000201:enzymology* / Q000648:ultrastructure; D014722:Vestibule, Labyrinth / Q000294:innervation*
chemical_list: D002256:Carbonic Anhydrases