title: Osteomyelitis of the skull base.
abstract: Osteomyelitis of the temporal bone often begins with minor trauma and results in a persistent external otitis. I report my experience with ten patients managed with combined medical and surgical therapy, and discuss the progression of the disease process and how it affects the duration of antibiotic therapy and the indications for planned surgical debridement. Early recognition of osteomyelitis of the temporal bone, combined with the aggressive use of long-term antibiotic therapy, in addition to planned surgical debridement, will reduce morbidity and potential mortality.
authors.forename: J
authors.initials: J
authors.lastname: Farrior
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use; D001299:Audiometry; D003131:Combined Modality Therapy; D003646:Debridement; D004334:Drug Administration Schedule; D005260:Female; D006310:Hearing Aids / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D010032:Otitis Externa / Q000209:etiology; D011552:Pseudomonas Infections / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D011550:Pseudomonas aeruginosa; D013701:Temporal Bone / Q000293:injuries
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents