Dietary zinc deficiency has no effect on auditory brainstem responses in the rat.
Zinc has been shown to effect--in vitro--a number of processes associated with neurotransmission. We have tested whether the rate of impulse conduction--in vivo--as measured from the latencies of auditory brainstem responses (ABR), is influenced by dietary zinc deficiency in the rat. Dietary zinc deficiency for up to 26 wk had no effect on the wave I-IV interval compared to zinc-adequate fed animals. The results are discussed in relation to the observed constancy of brain overall and extracellular fluid zinc concentrations under conditions of dietary zinc deficiency.
Wensink
J
J
Department of Radiochemistry, Technical University, Delft, The Netherlands.
Hoeve
H
H
Mertens zur Borg
I
I
Van den Hamer
C J
CJ
D000818:Animals; D001933:Brain Stem / Q000502:physiology*; D004032:Diet; D004594:Electrophysiology; D005072:Evoked Potentials, Auditory; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D014018:Tissue Distribution; D015032:Zinc / Q000172:deficiency* / Q000378:metabolism
D015032:Zinc