[Genotoxic effects of heavy metals and their salts in an experiment on Drosophila and mammals].
Analysis of data on the influence of different metals (cadmium, cobalt, molybdenum) on the Drosophila melanogaster cells has revealed a considerable genotoxic effect of cadmium salts which manifests in the high percentage of cells elimination at the early stages of spermatogenesis--the premeiotic cells. The modifying effect of molybdenum in the combination with cadmium and molybdenum decreasing the percentage of the progeny fall may be induced by activation of the reparation systems. In the bone marrow cells of mice Cd ions modify cytogenetic effects of the AB preparation, intensifying its mutagenic activity in some cases.
Chopikashvili
L V
LV
Bobyleva
L A
LA
Zolotareva
G N
GN
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects; D002104:Cadmium / Q000633:toxicity; D019256:Cadmium Chloride; D003035:Cobalt / Q000633:toxicity; D004331:Drosophila melanogaster / Q000235:genetics*; D005298:Fertility / Q000187:drug effects; D008670:Metals / Q000633:toxicity*; D008982:Molybdenum / Q000633:toxicity; D009153:Mutagens
D008670:Metals; D009153:Mutagens; D002104:Cadmium; D003035:Cobalt; D008982:Molybdenum; D019256:Cadmium Chloride; C022175:ammonium molybdate
Genotoksicheskie éffekty tiazhelykh metallov i ikh soleĭ v éksperimente na drozofile i mlekopitaiushchikh.