[Effects of Apocynum hendersonii (Hook. f.) Woodson on cardiac electric and mechanical activity].
Calcium antagonist-like effect of Apocynum hendersonii on myocardiac preparations was observed in the present experiments. The action potential duration and contractility were decreased. Automatic or exciting activity in partially depolarized fibers was considerably inhibited or concealed. Observation in vivo showed that pacemaking in SA node and conducting in AV node area were inhibited.
Han
D Y
DY
Lin
P
P
Qu
B L
BL
Chen
X L
XL
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D002036:Bundle of His / Q000502:physiology; D003864:Depression, Chemical; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004562:Electrocardiography; D005260:Female; D006168:Guinea Pigs; D006321:Heart / Q000187:drug effects* / Q000502:physiology; D066298:In Vitro Techniques; D008297:Male; D009200:Myocardial Contraction / Q000187:drug effects; D011690:Purkinje Fibers / Q000502:physiology; D011817:Rabbits
D004365:Drugs, Chinese Herbal