Heat shock induces c-fos protein-like immunoreactivity in glial cells in adult rat brain.
Heat shocking of anesthetized rats lead to a massive increase in c-fos protein-like immunoreactivity (FOS-IR) in glial-like cells in white and gray matter regions of the brain. Neuronal FOS-IR was not detectibly altered by heat shock. This induction of FOS-IR was present 1 h, but not 10 min or 24 h, after heat shock. These results demonstrate that c-fos protein is expressed in glial cells following thermal stress.
Dragunow
M
M
Department of Anatomy, School of Medicine, University of Auckland, New Zealand.
Currie
R W
RW
Robertson
H A
HA
Faull
R L
RL
D000818:Animals; D001921:Brain / Q000166:cytology*; D006651:Histocytochemistry; D006358:Hot Temperature; D007124:Immunoenzyme Techniques; D007700:Kinetics; D008297:Male; D009457:Neuroglia / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism; D011518:Proto-Oncogene Proteins / Q000096:biosynthesis*; D016760:Proto-Oncogene Proteins c-fos; D051381:Rats; D011919:Rats, Inbred Strains
D011518:Proto-Oncogene Proteins; D016760:Proto-Oncogene Proteins c-fos