[Transport of monosaccharides in model systems: inhibition of sugar transport in frog muscle fibers, treated with glutaraldehyde].
The entry of D-xylose, a permeable non-metabolizing glucose analog, in the frog muscle fibers was examined. The sugar transport system activity was established in the frog muscle fibers treated by 0.3% glutaraldehyde. The basal transport as well as insulin activated D-xylose transport was seen preserved. Sugar transport inhibitors, phlorizin, phloretin and cytochalasine B reduce the rate of D-xylose transport in this "glutar model" of a muscle fiber. A long treatment by glutaraldehyde (3.5 hours at 4 degrees C, and 1 hour at 20 degrees C) leads to a 40% decline in the entry rate of D-xylose.
Vasianin
S I
SI
Vinogradova
N A
NA
D000447:Aldehydes / Q000494:pharmacology*; D000818:Animals; D001001:Anura; D001692:Biological Transport; D003572:Cytochalasins / Q000494:pharmacology; D005976:Glutaral / Q000494:pharmacology*; D009132:Muscles / Q000187:drug effects*; D014994:Xylose / Q000037:antagonists & inhibitors / Q000493:pharmacokinetics*
D000447:Aldehydes; D003572:Cytochalasins; D014994:Xylose; D005976:Glutaral
Transport monosakharidov v modelnykh sistemakh: ingibirovanie transporta sakharov v myshechnykh voloknakh liagushki, obrabotannykh glutaral'degidom.