Dry drop of blood plasma--a new approach in the diagnosis of neoplastic diseases.
The dried drop of blood plasma and serum was first described by Białowas in 1967. The dry drop as a method for diagnosis of neoplasms was introduced in 1984 by Hungarian authors from Cancer Research Group. The aim of our investigations was to estimate the usefulness of this method in diagnostic of central nervous system's tumours and lung cancers. We worked out our own modification of dry drop test, i.e., we used the blood plasma instead the blood serum. In 93% of neoplasms the result of test was positive (in 92% of neoplasms of central nervous system and in 83% of lung cancers). In the control group occurred the large number of falsely positive results, as well as in group of patients with lung tuberculosis (70%), multiple sclerosis (63%) and myasthenia (45%). The results of our investigations showed the usefulness of this method in the screening diagnostic of neoplasia. The further investigations are necessary, especially correlation of dry drop test results with erythrocyte sedimentation test and antibodies and fibrinogen's level in the blood.
Brzecki
A
A
Department of Neurology, Medical Academy, Wrocław, Poland.
Brzecka
A
A
Gruszka
E
E
Olejniczak
P
P
Cyrul
M
M
D000328:Adult; D001774:Blood Chemical Analysis / Q000379:methods; D001932:Brain Neoplasms / Q000097:blood / Q000175:diagnosis / Q000473:pathology; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood / Q000175:diagnosis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000097:blood* / Q000175:diagnosis / Q000473:pathology; D013120:Spinal Cord Neoplasms / Q000097:blood / Q000175:diagnosis / Q000473:pathology