title: Clinical pharmacology and use of nonsteroidal anti-inflammatory drugs.
abstract: This review informs clinicians about current clinical usage and pharmacokinetics of newer NSAIDs and aspirin. To understand the effects of these drugs, a review of prostaglandin synthesis and actions is provided.
authors.affiliation: Section of Clinical Pharmacology/Toxicology, Ohio State University, Columbus.
authors.forename: M E
authors.initials: ME
authors.lastname: Mortensen
authors.forename: R M
authors.initials: RM
authors.lastname: Rennebohm
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000378:metabolism / Q000493:pharmacokinetics / Q000494:pharmacology*; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000378:metabolism; D001171:Arthritis, Juvenile / Q000188:drug therapy / Q000276:immunology; D001241:Aspirin / Q000494:pharmacology; D002648:Child; D002675:Child, Preschool; D004347:Drug Interactions; D015777:Eicosanoids / Q000037:antagonists & inhibitors / Q000096:biosynthesis; D006801:Humans; D007249:Inflammation / Q000188:drug therapy / Q000276:immunology; D011453:Prostaglandins / Q000096:biosynthesis / Q000502:physiology*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D001095:Arachidonic Acids; D015777:Eicosanoids; D011453:Prostaglandins; D016718:Arachidonic Acid; D001241:Aspirin