title: A simplified concept for a bileaflet atrioventricular valve that maintains annular-papillary muscle continuity.
abstract: We have developed a simplified concept for a bileaflet atrioventricular prosthesis that can be constructed from a simple sheet of glutaraldehyde preserved pericardium. The valve has no rigid ring or stent and no cloth sewing ring. Insertion of the valve reestablishes normal continuity between the annulus and the papillary muscles. We have replaced the mitral valve in nine dogs using this prosthesis. All valves have been competent with excellent valve opening areas as confirmed by echo-Doppler assessment. Studies up to 4 1/2 months have confirmed excellent hemodynamics and there has been no evidence of early tissue failure. Possible advantages of this simple valve design are improved hemodynamics, ease of construction and insertion, and low cost.
authors.affiliation: Division of Cardiovascular Surgery, Toronto General Hospital, Ontario, Canada.
authors.forename: L L
authors.initials: LL
authors.lastname: Mickleborough
authors.forename: Y
authors.initials: Y
authors.lastname: Ovil
authors.forename: G J
authors.initials: GJ
authors.lastname: Wilson
authors.forename: G
authors.initials: G
authors.lastname: Mishkel
authors.forename: T
authors.initials: T
authors.lastname: Tashiro
authors.forename: A
authors.initials: A
authors.lastname: Usui
authors.forename: H
authors.initials: H
authors.lastname: Rakowski
authors.forename: G
authors.initials: G
authors.lastname: Gray
authors.forename: B
authors.initials: B
authors.lastname: Goldman
mesh_terms: D000818:Animals; D001705:Bioprosthesis; D002102:Cadaver; D004285:Dogs; D004452:Echocardiography; D005976:Glutaral; D006350:Heart Valve Prosthesis; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008943:Mitral Valve; D010210:Papillary Muscles / Q000502:physiology; D010496:Pericardium; D011474:Prosthesis Design
chemical_list: D005976:Glutaral