title: [Adverse reactions caused by drugs in pediatrics].
abstract: The present study describes the results obtained in a screening program aimed at detecting adverse reactions to medication in children aged 1-8 years admitted to the Pediatrics Service of the University of Granada Hospital (Spain). The program is based on monitoring the patients for a period of 12 months. Of a total of 597 patients, adverse reactions were recorded in 4.4%. Within this group the reactions were classified as confirmed in 33.3%, probable in 30% and possible in 36.6%. Based on organs and systems, the CNS was most frequently affected (40%), followed in decreasing order by the digestive (37%) and cardiovascular systems (10%), skin (10%) and endocrine system (3%). The drugs most frequently involved were bronchodilators (40%), antibiotics (30%) and antiepileptics (20%). Among risk factors, polytherapy, hospitalization time and type of drug administered were the most important.
authors.affiliation: Servicio de Pediatría, Hospital Universitario, Granada.
authors.forename: A
authors.initials: A
authors.lastname: Vázquez de la Villa
authors.forename: J D
authors.initials: JD
authors.lastname: Luna del Castillo
authors.forename: G
authors.initials: G
authors.lastname: Galdó Muñoz
authors.forename: E
authors.initials: E
authors.lastname: Puche Cañas
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D000927:Anticonvulsants / Q000009:adverse effects*; D001993:Bronchodilator Agents / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000139:chemically induced*; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012307:Risk Factors; D014839:Vomiting / Q000139:chemically induced*
chemical_list: D000900:Anti-Bacterial Agents; D000927:Anticonvulsants; D001993:Bronchodilator Agents
vernacular_title: Reacciones adversas causadas por medicamentos en pediatría.