[The results of the conservative treatment of patients with small-cell lung cancer].
The results of conservative treatment of 246 cases of small-cell cancer of the lung at The All-Union Center for Oncology Research of the USSR Academy of Medical Sciences (1974-1982) are discussed. Survival for two years was registered in 45 cases (18%), 2.5 years--10% and three years--in 7%. Twelve survivors (5%) have had a 5-13-year tumor-free interval and are considered cured. Five--year survival and more was observed only in patients with localized tumors who had received both combination chemotherapy and chemoradiation treatment. Prophylactic irradiation of the brain did not improve 2- or 5-year survival. The evidence on the role of chemotherapeutic support remains inconclusive. A second malignancy was detected in 2 of 45 patients 3 and 5 years after complete remission.
Bychko
M B
MB
Ol'khovskaia
I G
IG
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018288:Carcinoma, Small Cell / Q000401:mortality / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D011879:Radiotherapy Dosage; D014586:USSR
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