title: [Immunoregulatory disorders and the proliferative activity of T- and B-lymphocytes in osteoarthrosis].
abstract: The authors studied the activity of nuclear chromatin of the peripheral T- and B-lymphocytes in the polyclonal activation test using the method of quantitative cytofluorometry. A new experimental model in vitro has been proposed for the study of regulatory function of T-lymphocytes. It was found out that in approximately 50% of osteoarthrosis patients the greater part of the peripheral lymphoid population is in the state of initial activation and the activated B-lymphocytes occur more frequently than T-lymphocytes.
authors.forename: E V
authors.initials: EV
authors.lastname: Benenson
authors.forename: E G
authors.initials: EG
authors.lastname: Tsaĭ
authors.forename: A S
authors.initials: AS
authors.lastname: Tabyshalieva
mesh_terms: D000328:Adult; D000367:Age Factors; D001402:B-Lymphocytes / Q000276:immunology* / Q000473:pathology; D002455:Cell Division; D006801:Humans; D066298:In Vitro Techniques; D008213:Lymphocyte Activation / Q000187:drug effects; D008875:Middle Aged; D008934:Mitogens / Q000494:pharmacology; D010003:Osteoarthritis / Q000276:immunology* / Q000473:pathology; D013601:T-Lymphocytes / Q000276:immunology* / Q000473:pathology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology / Q000473:pathology
chemical_list: D008934:Mitogens
vernacular_title: Immunoreguliatornye narusheniia i proliferativnaia aktivnos't T- i B-limfotsitov pri osteoartroze.