title: Structure of the ATP-synthase studied by electron microscopy and image processing.
abstract: The structure of ATP synthase from beef heart mitochondria has been studied by electron microscopy and image processing using negatively stained specimens of detergent-solubilized and membrane-bound molecules. The F1-ATPase and the membrane-embedded F0 sector of ATP synthase are found to be connected by a narrow stalk, 4-4.5 nm long and 3-3.5 nm wide, projecting about 4.2 nm from the membrane surface. The F0 sector has a globular shape, 6-8 nm in diameter and, in part, extends from the membrane lipid bilayer.
authors.affiliation: A.V. Shubnikov Institute of Crystallography, USSR Academy of Sciences, Moscow.
authors.forename: V L
authors.initials: VL
authors.lastname: Tsuprun
authors.forename: E V
authors.initials: EV
authors.lastname: Orlova
authors.forename: I V
authors.initials: IV
authors.lastname: Mesyanzhinova
mesh_terms: D000818:Animals; D002417:Cattle; D003196:Computer Graphics; D008565:Membrane Proteins / Q000648:ultrastructure; D008854:Microscopy, Electron; D008929:Mitochondria, Heart / Q000201:enzymology*; D006180:Proton-Translocating ATPases; D013367:Submitochondrial Particles / Q000201:enzymology* / Q000648:ultrastructure
chemical_list: D008565:Membrane Proteins; D006180:Proton-Translocating ATPases