Negative correlation of cigarette smoking and dysmenorrhea: reduced prostaglandin synthesis due to beta-endorphin, nicotine, or acrolein antagonism.
It is suggested that the mechanism for decreased incidence of dysmenorrhea in female cigarette smokers may lie in the possible inhibition of algesic prostaglandins smoking induced stimulation of beta-endorphin, nicotine, or acrolein.
Backon
J
J
Mount Pleasant Hospital Addiction Studies Foundation, Mount Pleasant Hospital, Lynn, MA.
D000171:Acrolein / Q000494:pharmacology*; D000447:Aldehydes / Q000494:pharmacology*; D000527:Alprostadil / Q000037:antagonists & inhibitors; D004412:Dysmenorrhea / Q000097:blood*; D005260:Female; D006801:Humans; D009538:Nicotine / Q000494:pharmacology*; D011448:Prostaglandin Antagonists / Q000494:pharmacology*; D012907:Smoking / Q000097:blood*; D001615:beta-Endorphin / Q000097:blood*
D000447:Aldehydes; D011448:Prostaglandin Antagonists; D001615:beta-Endorphin; D009538:Nicotine; D000171:Acrolein; D000527:Alprostadil