title: [Germ cell tumors in childhood].
abstract: This report concerns 33 infants and children with germ cell tumours = teratomas treated between 1968 and 1986. The primary site of the tumour was sacrococcygeal in 12 and the ovaries in 10. Malignancy occurred in 9 out of 33 (= 27%) patients. To prevent malignant transformation, early surgical intervention has to be performed in benign tumours. For immature subtypes as well as incomplete tumour extirpation a short-term follow-up should be mandatory. The recent change of treatment in malignant teratomas (protochemotherapy, delayed tumour extirpation, improved drugs, second-look operation)--based on cooperative interdisciplinary therapy studies--is discussed. Ultrasound and tumour markers are recommended as good indicators for diagnostic and follow-up studies.
authors.affiliation: Abteilung für Kinderchirurgie, I. Universitätsklinik für Chirurgie, Innsbruck.
authors.forename: J
authors.initials: J
authors.lastname: Hager
authors.forename: G
authors.initials: G
authors.lastname: Menardi
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D006258:Head and Neck Neoplasms / Q000601:surgery; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008479:Mediastinal Neoplasms / Q000601:surgery; D009373:Neoplasms, Germ Cell and Embryonal / Q000601:surgery*; D010051:Ovarian Neoplasms / Q000601:surgery; D011379:Prognosis; D012186:Retroperitoneal Neoplasms / Q000601:surgery; D012447:Sacrum / Q000601:surgery; D013125:Spinal Neoplasms / Q000601:surgery; D013724:Teratoma / Q000601:surgery
vernacular_title: Keimzelltumoren im Kindesalter.