Glucocorticosteroid replacement therapy: a literature review and suggested replacement therapy.
Administration of exogenous glucocorticosteroids will cause adrenal suppression lasting for up to 12 months; however, the patient's stress response will return within 14 to 30 days. This difference occurs as a result of the effects of corticotropin-releasing factor on the autonomic nervous system and on visceral systems. A new protocol for glucocorticosteroid replacement therapy is proposed that is based on the patient's ability to respond to dental stress.
Glick
M
M
Department of Oral Medicine, Temple University School of Dentistry, Philadelphia, Pa.
D000311:Adrenal Glands / Q000187:drug effects / Q000378:metabolism; D003730:Dental Care for Persons with Disabilities; D005938:Glucocorticoids / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use*; D006801:Humans; D013312:Stress, Physiological / Q000503:physiopathology
D005938:Glucocorticoids