title: Granular cell tumor of the stomach coincident with two early gastric carcinomas.
abstract: In a 64-yr-old Japanese man, granular cell tumor of the stomach plus two early gastric carcinomas were detected. The granular cell tumor was a 1.5 x 1.5-cm submucosal nodule located in the posterior wall of the fundus. The mucosa adjacent to the granular cell tumor showed two well-differentiated adenocarcinomas restricted to the mucosa, but there was no continuity among these three conditions. This seems to be the first report of this type of association. Immunohistochemical study revealed S-100 protein in the component cells of the granular cell tumor, thereby supporting the proposal that this granular cell is derived from Schwann cells.
authors.affiliation: Department of Surgery, Shin Kokura Hospital, Kitakyushu, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Yamaguchi
authors.forename: S
authors.initials: S
authors.lastname: Maeda
authors.forename: K
authors.initials: K
authors.lastname: Kitamura
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000912:Antibodies, Neoplasm / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009379:Neoplasms, Muscle Tissue / Q000276:immunology / Q000473:pathology*; D013274:Stomach Neoplasms / Q000276:immunology / Q000473:pathology*
chemical_list: D000912:Antibodies, Neoplasm