title: Sequential observation of clinical and karyotypic evolution in a patient with myelodysplastic syndrome.
abstract: This paper reports an interesting case of myelodysplastic syndrome (MDS), whose bone marrow karyotype at diagnosis was 46, XY, t(16;17) (q12;q25). Fourteen months later, the disease transformed into erythroleukemia, and several correlative clones with hyperdiploid appeared at the same time. Thus, we consider that detecting karyotypic evolution may help evaluate the prognosis of MDS.
authors.forename: Y Q
authors.initials: YQ
authors.lastname: Xue
authors.forename: Y
authors.initials: Y
authors.lastname: Guo
authors.forename: B J
authors.initials: BJ
authors.lastname: Lin
authors.forename: G R
authors.initials: GR
authors.lastname: Zhang
authors.forename: D W
authors.initials: DW
authors.lastname: Lu
authors.forename: M H
authors.initials: MH
authors.lastname: Wang
authors.forename: Y Z
authors.initials: YZ
authors.lastname: Gu
authors.forename: J X
authors.initials: JX
authors.lastname: Gong
authors.forename: L X
authors.initials: LX
authors.lastname: Wang
mesh_terms: D000753:Anemia, Refractory / Q000235:genetics / Q000473:pathology; D001853:Bone Marrow / Q000473:pathology; D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D002885:Chromosomes, Human, Pair 16; D002886:Chromosomes, Human, Pair 17; D006801:Humans; D007621:Karyotyping; D004915:Leukemia, Erythroblastic, Acute / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000235:genetics* / Q000473:pathology; D011379:Prognosis