[Prevention of abscess of the abdominal wall by continuous antisepsis, combined with antibiotherapy. 4751 cases].
The reduced incidence of wall abscesses following routine general surgery was studied in 4751 cases over the period from 1973 to 1987. The therapeutical evolution spanned over three consecutive treatment periods, each one falling into one patient group. The reference period (Group I) extended from 1973 to 1978. Starting from 1978 and up till 1984 (Group 2), systematic repeated lavage of the operative field with an iodized polyvinylpyrrolidone solution were carried out, providing thus for true continuous antisepsis (CA). Starting from 1985 (Group 3), the method of continuous antisepsis was associated with systematic prophylactic antibiotherapy (SPAB). Groups 1, 2 and 3 included 2051, 1955 and 745 cases, respectively, and presented progressively decreasing rates of abscess formation (4%, 2.5%, 1.7%, respectively). In order to better assess these results, an in-depth analysis was carried out on two types of surgical operations, i.e., appendicitis and gynecological surgery, based on Altemeier's classification. The rate of abscess formation was lowered. This result is particularly interesting from the point of view of gynecological surgery, inasmuch as a relative increase in the frequency of the more esthetic horizontal incisions is being concurrently noted.
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Laboratoires Sarget, Département Recherche Clinique, Mérignac.
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D000009:Abdominal Muscles; D000038:Abscess / Q000188:drug therapy / Q000517:prevention & control*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000985:Antisepsis / Q000379:methods*; D001062:Appendectomy; D005260:Female; D005836:Genitalia, Female / Q000601:surgery; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D013997:Time Factors
D000900:Anti-Bacterial Agents
Prévention des abcès de paroi par l'antisepsie continue, associée à l'antibiothérapie. 4751 observations.