title: Synthesis and in vitro effects on platelets and vascular smooth muscle of S-145, a novel thromboxane receptor antagonist.
authors.affiliation: Shionogi Research Laboratories, Shionogi & Co., Ltd., Osaka, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Narisada
authors.forename: M
authors.initials: M
authors.lastname: Ohtani
authors.forename: F
authors.initials: F
authors.lastname: Watanabe
authors.forename: K
authors.initials: K
authors.lastname: Uchida
authors.forename: H
authors.initials: H
authors.lastname: Arita
authors.forename: M
authors.initials: M
authors.lastname: Doteuchi
authors.forename: M
authors.initials: M
authors.lastname: Ueda
authors.forename: K
authors.initials: K
authors.lastname: Hanasaki
authors.forename: H
authors.initials: H
authors.lastname: Kakushi
authors.forename: K
authors.initials: K
authors.lastname: Otani
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000187:drug effects* / Q000502:physiology; D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis* / Q000494:pharmacology; D001952:Bridged-Ring Compounds / Q000138:chemical synthesis*; D005229:Fatty Acids, Monounsaturated / Q000138:chemical synthesis* / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D007202:Indicators and Reagents; D009131:Muscle, Smooth, Vascular / Q000187:drug effects* / Q000502:physiology; D011982:Receptors, Prostaglandin / Q000187:drug effects* / Q000378:metabolism; D013329:Structure-Activity Relationship
chemical_list: D001643:Bridged Bicyclo Compounds; D001952:Bridged-Ring Compounds; D005229:Fatty Acids, Monounsaturated; D007202:Indicators and Reagents; D011982:Receptors, Prostaglandin; C056566:S 145