title: [The value of positive epicutaneous test reactions to 4,4'-diaminodiphenylmethane].
abstract: This study was undertaken to determine the significance of positive patch test reactions to 4,4'-diaminodiphenylmethane (DDM). Data of 202 DDM-positive patients concerning age, sex and profession, type, localisation and duration of eczema and combined allergens were evaluated. The results obtained were compared by chi-square-test with those of 3397 consecutive, unselected contact dermatitis patients with negative reactions to DDM. The most conspicuous results were: 1. The positive patch test reaction to DDM is usually a marker for allergy to p-amino-compounds. 2. 39/202 patients showed isolated positive test reactions to DDM. The source of the allergen remained unclear. 3. Workers in chemical laboratories seem to have an increased risk for acquiring DDM-allergy. 4. The clinical relevance of DDM-allergy could only be proven in a few patients.
authors.affiliation: Universitätsklinik für Dermatologie und Venerologie, Graz Osterreich.
authors.forename: G
authors.initials: G
authors.lastname: Gailhofer
authors.forename: M
authors.initials: M
authors.lastname: Ludvan
mesh_terms: D000328:Adult; D000368:Aged; D000814:Aniline Compounds / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000209:etiology; D009783:Dermatitis, Occupational / Q000139:chemically induced; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D012882:Skin Tests; D001559:Benzhydryl Compounds
chemical_list: D000814:Aniline Compounds; C009505:4,4'-diaminodiphenylmethane; D001559:Benzhydryl Compounds
vernacular_title: Zur Wertigkeit positiver Epikutantestreaktionen auf 4,4'-Diaminodiphenylmethan.