[Comparative study of 2 common tests for lupus anticoagulant determination: critical analysis of the results observed in 21 patients].
The Schleider and/or the Exner test have been found positive in twenty-one patients; five of these patients suffered of systemic lupus erythematosus (SLE). The Quick time and the activated partial thromboplastin time are normal in 52% of the cases. 40% have a minor haemorrhagic diathesis, without other significant clotting defect and 30% have thrombo-embolic complications. The Schleider index is more often strongly positive (greater than 2) in these two groups. 58% have an anemia, 25% a mild thrombocytopenia not deep enough to explain an haemorrhagic tendency (from 90.000 to 140.000/mm3). Several auto-immune tests are frequently positive even without SLE. The Schleider test is positive in 86% of the cases and appears a little more useful for the diagnosis than the Exner test, which has a 71% positivity.
Efira
A
A
Capel
P
P
Roose
A
A
Bitar
N
N
Rauis
M
M
Cauchie
P
P
Fondu
P
P
D000293:Adolescent; D000328:Adult; D000368:Aged; D001779:Blood Coagulation Factors / Q000032:analysis / Q000276:immunology*; D001780:Blood Coagulation Tests; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D016682:Lupus Coagulation Inhibitor; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
D001779:Blood Coagulation Factors; D016682:Lupus Coagulation Inhibitor
Etude comparative de deux tests usuels de dépistage de l'anticoagulant du lupus: analyse critique des résultats observés chez 21 malades.