Cutaneous fibrinolytic potential, tPA dependent, is reduced in Behçet's disease.
We report our studies on the cutaneous and plasma fibrinolytic activities (FA) in nine patients with Behçet's disease (BD) as compared with nine normal controls. The euglobulin lysis time of the plasma and cutaneous fibrinolytic activity were determined in these patients. The studies showed that the plasma fibrinolytic activity was reduced in the patients with BD and there was impaired cutaneous fibrinolytic potential, tPA dependent, in those patients with venous and arterial thromboses.
Lotti
T
T
Istituto di Clinica Dermatologia, University of Florence, Italy.
Matucci-Cerinic
M
M
D000328:Adult; D001528:Behcet Syndrome / Q000378:metabolism* / Q000503:physiopathology; D005342:Fibrinolysis / Q000502:physiology*; D006632:Histamine; D006801:Humans; D008875:Middle Aged; D012867:Skin / Q000378:metabolism*; D010959:Tissue Plasminogen Activator / Q000378:metabolism*
D006632:Histamine; D010959:Tissue Plasminogen Activator