A new polymorphic variant of human complement factor I.
Sera from 305 individuals were typed for factor I, and a new variant, tentatively designated FI C, was found. All other samples were FI B except for seven samples from Chinese that were of the FI AB phenotype. This suggests that polymorphism of factor I may be rare in Caucasians.
Zhou
M
M
Memorial University of Newfoundland, School of Medicine, St. John's, Canada.
Larsen
B
B
D003180:Complement C3b Inactivator Proteins / Q000235:genetics*; D017244:Complement Factor I; D006801:Humans; D011110:Polymorphism, Genetic; D012697:Serine Endopeptidases / Q000235:genetics*
D003180:Complement C3b Inactivator Proteins; D012697:Serine Endopeptidases; D017244:Complement Factor I