[The direct and indirect antiaggregation action of sodium hypochlorite on thrombocyte-enriched blood plasma].
Sodium hypochlorite produces an indirect anti-aggregation action on platelets in platelet-rich plasma. This effect seems to be the result of the reversible reaction between platelets and products of plasma modification. High rate constants are characteristic of hypochlorite interaction with SH and SS groups of glutathione, as well as bilirubin.
Murina
M A
MA
Sergienko
V I
VI
hupkin
D I
DI
D000409:Alanine / Q000097:blood; D000818:Animals; D001663:Bilirubin / Q000097:blood; D001792:Blood Platelets / Q000187:drug effects* / Q000502:physiology; D004347:Drug Interactions; D005978:Glutathione / Q000097:blood; D010949:Plasma / Q000187:drug effects* / Q000502:physiology; D010974:Platelet Aggregation / Q000187:drug effects* / Q000502:physiology; D010975:Platelet Aggregation Inhibitors; D011817:Rabbits; D012694:Serine / Q000097:blood; D012973:Sodium Hypochlorite / Q000494:pharmacology*
D010975:Platelet Aggregation Inhibitors; D012694:Serine; D012973:Sodium Hypochlorite; D005978:Glutathione; D000409:Alanine; D001663:Bilirubin
Priamoe i kosvennoe protivoagregatsionnoe deĭstvie gipokhlorita natriia na obogashchennuiu trombotsitami plazmu krovi.