title: Mouse brain Tau proteins: microheterogeneity and phosphorylation.
abstract: Tau proteins are involved in polymerization of tubulin into microtubules. They comprise a heterogeneous group of proteins that can be resolved by two-dimensional gel electrophoresis using a non-equilibrium pH gradient in the first dimension. Developmental studies show that mouse brain Tau proteins are more heterogeneous in 15-day old mice than in newborn pups or adults. Tau phosphorylation is also more heterogeneous at this stage.
authors.affiliation: Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Brasil.
authors.forename: H M
authors.initials: HM
authors.lastname: Araujo
authors.forename: R P
authors.initials: RP
authors.lastname: Keller
authors.forename: A
authors.initials: A
authors.lastname: Fellous
authors.forename: C
authors.initials: C
authors.lastname: Chagas
authors.forename: V
authors.initials: V
authors.lastname: Moura-Neto
mesh_terms: D000818:Animals; D001345:Autoradiography; D001921:Brain / Q000378:metabolism*; D015180:Electrophoresis, Gel, Two-Dimensional; D051379:Mice; D008869:Microtubule-Associated Proteins / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism*; D010766:Phosphorylation; D016875:tau Proteins
chemical_list: D008869:Microtubule-Associated Proteins; D016875:tau Proteins