title: Distribution of glycoconjugates in human skin appendages.
abstract: The purpose of this paper is to describe the occurrence and distribution of glycoconjugates in normal human epidermis and skin appendages (pilosebaceous unit, eccrine sweat gland) by means of FITC-labelled lectins (ConA, WGA, UEA I). Both the outer hair root and the follicular ostium-epithel disclosed a glycoconjugate expression with close homology to interfollicular epidermis. The acinar epithelium of sebaceous glands and the inner layers of hair follicles showed a more or less distinct staining pattern. Lectin binding of eccrine sweat glands revealed marked differences between ducts and secretory coils. The epithelial distribution of glycoconjugates indicates a relatively independent differentiation pathway of eccrine sweat glands compared with other specialized epithelia of the human skin.
authors.affiliation: Department of Medicine, Friedrich-Schiller University Jena, GDR.
authors.forename: U
authors.initials: U
authors.lastname: Wollina
authors.forename: H H
authors.initials: HH
authors.lastname: Schaarschmidt
authors.forename: C
authors.initials: C
authors.lastname: Hipler
authors.forename: B
authors.initials: B
authors.lastname: Knopf
mesh_terms: D000117:Acetylglucosamine / Q000032:analysis; D000328:Adult; D002462:Cell Membrane / Q000648:ultrastructure; D004439:Eccrine Glands / Q000166:cytology; D000078404:Epidermal Cells; D016650:Fluorescein-5-isothiocyanate; D005452:Fluoresceins; D005456:Fluorescent Dyes; D005643:Fucose / Q000032:analysis; D006001:Glycoconjugates / Q000032:analysis*; D006197:Hair / Q000166:cytology; D006801:Humans; D037102:Lectins; D012627:Sebaceous Glands / Q000166:cytology; D012794:Sialic Acids / Q000032:analysis; D012867:Skin / Q000166:cytology*; D013861:Thiocyanates
chemical_list: D005452:Fluoresceins; D005456:Fluorescent Dyes; D006001:Glycoconjugates; D037102:Lectins; D012794:Sialic Acids; D013861:Thiocyanates; D005643:Fucose; D016650:Fluorescein-5-isothiocyanate; D000117:Acetylglucosamine