[The possibility of intensifying endogenous nitrogen reutilization in protein starvation by the parental administration of small doses of methionine and threonine].
Experiments conducted on albino Wistar male rats showed that endogenous nitrogen reutilization can be intensified by parenteral administration of regulatory amino acids methionine and threonine and their mixture in doses of 100-200 mg/kg in short-term protein deprivation. The data obtained may be used in clinical practice to reduce nitrogen excretion from the patient's organism with the patient deprived of food in the early postoperative period.
Magarlamov
A G
AG
Levchenko
I V
IV
Ishchuk
O E
OE
Anoshina
M Iu
MIu
D000818:Animals; D004044:Dietary Proteins / Q000008:administration & dosage; D004353:Drug Evaluation, Preclinical; D005243:Feces / Q000032:analysis; D007263:Infusions, Parenteral; D008297:Male; D008715:Methionine / Q000008:administration & dosage*; D009584:Nitrogen / Q000378:metabolism*; D011502:Protein-Energy Malnutrition / Q000188:drug therapy / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013217:Starvation / Q000188:drug therapy / Q000378:metabolism*; D013912:Threonine / Q000008:administration & dosage*
D004044:Dietary Proteins; D013912:Threonine; D008715:Methionine; D009584:Nitrogen
Vozmozhnost' usileniia reutilizatsii éndogennogo azota v usloviiakh belkovogo golodaniia parenteral'nym vvedeniem malykh doz metionina i treonina.