title: [Amino acid derivatives of 2,6 and p-aminobenzoic acid. I. Synthesis of derivatives of 2,6-xylidine and various derivatives of PAB].
abstract: Syntheses of amino acid derivatives of p-aminobenzoic acid and 2,6-xylidine, potential antiarrhythmic agents are described. The carbodiimide method and the method of mixed anhydrides were employed for the syntheses. Physicochemical properties, yields, data of elementary analysis, and IR and 1H-NMR spectra of eighteen novel compounds are given.
authors.forename: W
authors.initials: W
authors.lastname: Kwapiszewski
authors.forename: E
authors.initials: E
authors.lastname: Piranowicz-Chaber
authors.forename: L
authors.initials: L
authors.lastname: Skulski
mesh_terms: D010129:4-Aminobenzoic Acid / Q000138:chemical synthesis*; D000814:Aniline Compounds / Q000138:chemical synthesis*; D000889:Anti-Arrhythmia Agents; D001145:Arrhythmias, Cardiac / Q000188:drug therapy*; D055598:Chemical Phenomena; D002621:Chemistry; D004341:Drug Evaluation; D006801:Humans; D008012:Lidocaine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000627:therapeutic use*; D011342:Procainamide / Q000138:chemical synthesis / Q000627:therapeutic use*; D016677:Tocainide
chemical_list: D000814:Aniline Compounds; D000889:Anti-Arrhythmia Agents; D016677:Tocainide; C007766:2,6-xylidine; D008012:Lidocaine; D011342:Procainamide; D010129:4-Aminobenzoic Acid
vernacular_title: Aminokwasowe pochodne 2,6-ksylidyny i kwasu p-amino-benzoesowego. I. Otrzymywanie pochodnych 2,6-ksylidyny i niektórych pochodnych PAB-u.