[Evaluation of biological equivalency of Sustonit (Polfa) and Sustac by plethysmography].
Bioequivalence of Sustonit tablets (2.6 and 6.5 mg) produced at WZF Polfa and Sustac tablets (2.6 and 6.5 mg) made by Krka (Yugoslavia) and WZF Polfa (Poland) was studied by means of the digital plethysmography. All the three drugs with the nitroglycerin content of 2.6 mg were found to be biologically equivalent. On the other hand, Sustonit (WZF Polfa) and Sustac (Krka) tablets with 6.5 mg nitroglycerin proved to possess better bioavailability than Sustac (6.5 mg) tablets produced previously at WZF Polfa.
Filczewski
M
M
Sadowski
Z
Z
Kobylińska
M
M
D000328:Adult; D003692:Delayed-Action Preparations; D004353:Drug Evaluation, Preclinical; D005385:Fingers / Q000098:blood supply*; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D005996:Nitroglycerin / Q000008:administration & dosage / Q000493:pharmacokinetics*; D010992:Plethysmography, Impedance / Q000379:methods; D011044:Poland; D013608:Tablets, Enteric-Coated; D015022:Yugoslavia
D003692:Delayed-Action Preparations; D013608:Tablets, Enteric-Coated; D005996:Nitroglycerin
Ocena biorównowazności preparatów sustonit polfa z preparatami sustac przy uzyciu metody pletysmograficznej.