Metastatic renal cell carcinoma arising in a congenital solitary kidney. Treatment with interferon-containing combinations. A case report and a review of the literature.
Renal Cell Carcinoma (RCC) in a single kidney is a rare occurrence, more so when it concerns agenesis of the kidney. Chemotherapy of metastatic renal cell carcinoma has a poor effect. We report a case of a man, 49 years of age, with agenesis of one kidney, admitted with a metastatic RCC of his only kidney. Survival of 15 months duration was achieved by therapy combining Provera, Vinblastine and Alpha-C-Recombinant Interferon.
Merimsky
O
O
Department of Oncology, Tel-Aviv Medical Center, Israel.
Laufer
R
R
Chaitchik
S
S
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002292:Carcinoma, Renal Cell / Q000188:drug therapy / Q000556:secondary*; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use; D007668:Kidney / Q000002:abnormalities*; D007680:Kidney Neoplasms / Q000188:drug therapy*; D008297:Male; D008525:Medroxyprogesterone / Q000031:analogs & derivatives / Q000627:therapeutic use; D017258:Medroxyprogesterone Acetate; D008875:Middle Aged; D011994:Recombinant Proteins; D014747:Vinblastine / Q000627:therapeutic use
D007370:Interferon Type I; D011994:Recombinant Proteins; D014747:Vinblastine; D017258:Medroxyprogesterone Acetate; D008525:Medroxyprogesterone