[Monoclonal antibodies OKT4 and OKT8 in the evaluation of cellular immunity in children with recurrent bronchitis].
The study aimed at evaluating cellular immunity in children with recurrent bronchitis with the aid of T-cells evaluation with rosette test and their subpopulations with monoclonal antibodies. The study involved 50 children aged between 2 and 14 years and 30 healthy children. Significant decrease in the absolute number and percentage of T-cells was seen in children with recurrent bronchitis. This decrease seemed apparent and probably resulted from the changes in receptors for sheep erythrocytes. Determination of T-cells subpopulation were within normal values as well as helper T-cells and suppressor T-cells ratio.
Breborowicz
A
A
Kołecki
P
P
D000293:Adolescent; D000945:Antigens, Differentiation, T-Lymphocyte; D001991:Bronchitis / Q000276:immunology*; D015704:CD4 Antigens; D016827:CD8 Antigens; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007111:Immunity, Cellular / Q000502:physiology; D007958:Leukocyte Count; D012008:Recurrence; D013601:T-Lymphocytes; D006377:T-Lymphocytes, Helper-Inducer; D050378:T-Lymphocytes, Regulatory
D000945:Antigens, Differentiation, T-Lymphocyte; D015704:CD4 Antigens; D016827:CD8 Antigens
Przeciwciała monoklonalne okt 4 i okt 8 w ocenie odporności komórkowej u dzieci z nawracajacymi zapaleniami oskrzeli.