[The relation of B- and non-A, non-B hepatitis virus--hepatitis B virus (HBV) DNA hybridization studies of the sera in non-A, non-B hepatitis].
Referring to informations of various international groups of investigators who regard the NANBH as HBV-variant the sera of 77 female patients with chronic NANBH and 28 acute phase sera of a NANBH serum bank were tested for HBV-DNA. The sera in question were such ones of a particularly well defined group of patients with unique parenteral source of infections. Though further ALAT attacks were observed, in none of the NANBH-sera HBV-DNA was proved as a sign of an active HBV-replication. This, like the absence of an immunity against the NANBH-virus after HBV-disease and the observed suppression of the HBV-DNA in NANBH-superinfection of HBV-carriers (virus interference), speaks against the hypothesis of a close genetic relationship between the two viruses.
Wiese
M
M
Klinik für Infektions- und Tropenkrankheiten, Bezirkskrankenhauses St. Georg Leipzig.
Meisel
H
H
D000328:Adult; D001706:Biopsy; D003001:Cloning, Molecular; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D006509:Hepatitis B / Q000175:diagnosis*; D006515:Hepatitis B virus / Q000302:isolation & purification*; D006526:Hepatitis C / Q000175:diagnosis*; D006521:Hepatitis, Chronic / Q000175:diagnosis; D006525:Hepatitis, Viral, Human / Q000175:diagnosis*; D006801:Humans; D008099:Liver / Q000473:pathology; D009693:Nucleic Acid Hybridization
D004279:DNA, Viral
Zum Verhältnis von B- und NonA-NonB-Hepatitisvirus - Hepatitis-B-Virus (HBV)-DNA-Hybridisierungsuntersuchungen in Seren von NonA-NonB-Hepatitiden.