[The action of triftorfenazin on the Ca-ATPase activity of fibroblasts and Ehrlich ascites cells].
The authors studied the mechanisms underlying the increase of the Ca-ATPase activity in tumoral cells. The kinetic analysis showed that Michaelis constant for ATP was higher in comparison with proliferating cells.
Chikvashvili
D V
DV
Shurgaia
I G
IG
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002118:Calcium / Q000378:metabolism; D000252:Calcium-Transporting ATPases / Q000378:metabolism*; D002147:Calmodulin / Q000378:metabolism; D002286:Carcinoma, Ehrlich Tumor / Q000201:enzymology*; D002462:Cell Membrane / Q000187:drug effects / Q000201:enzymology; D004305:Dose-Response Relationship, Drug; D005347:Fibroblasts / Q000187:drug effects* / Q000201:enzymology; D010619:Phenazines / Q000494:pharmacology*; D013379:Substrate Specificity / Q000187:drug effects
D002147:Calmodulin; D010619:Phenazines; D000255:Adenosine Triphosphate; D000252:Calcium-Transporting ATPases; D002118:Calcium
Deĭstvie triftorfenazina na aktivnost' Ca-ATFazy fibroblastov i astsitnykh kletok Erlikha.