title: In situ carcinoma of the breast.
abstract: In situ carcinoma of the breast is a proliferation of potentially malignant cells within the lumen of the ductal-lobular system and is classified as ductal or lobular in type. It has become an increasingly frequent clinical management problem, primarily because of its enhanced detection by screening mammography. In this paper, we discuss the problems in histologic diagnosis, the natural history, presentation, and options for management of these two forms of in situ carcinoma.
authors.affiliation: Department of Pathology, Beth Israel Hospital, Boston, Massachusetts 02130.
authors.forename: J L
authors.initials: JL
authors.lastname: Connolly
authors.forename: J
authors.initials: J
authors.lastname: Boyages
authors.forename: S J
authors.initials: SJ
authors.lastname: Schnitt
authors.forename: A
authors.initials: A
authors.lastname: Recht
authors.forename: W
authors.initials: W
authors.lastname: Silen
authors.forename: N
authors.initials: N
authors.lastname: Sadowsky
authors.forename: J R
authors.initials: JR
authors.lastname: Harris
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis / Q000628:therapy; D002278:Carcinoma in Situ / Q000175:diagnosis / Q000628:therapy; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans