title: [Maternal-child transmission of Chlamydia trachomatis. A prospective inquiry in 168 pregnant women].
abstract: A prospective study was performed in 168 pregnant women in order to evaluate the frequency of perinatal transmission of Chlamydia trachomatis and to measure its effects on the child's health during his first 3 months of life. The micro-organism was detected by an immunoenzymatic method specific to Chlamydia antigens, and microimmunofluorescence was used for serological testing. Cervical smears taken at the end of pregnancy were positive in 3 women (1.7 per cent), while the sera of 37 women were positive for Chlamydia trachomatis. Altogether, 26.8 per cent of the women explored had had a contact with the micro-organism. Conjunctival smears taken from 1 month old infants were all negative, but 4 infants (out of 126) had positive nasal smears. The mothers of 2 of these had been exposed to the bacterium, but all 4 mothers had negative cervical smears. Antibody titres in 3-month old infants were 1.2 dilution on average below those found in the mothers. Women exposed to Chlamydia trachomatis are frequently unmarried; their pregnancies tend to shorter than normally, and their infants have more frequent episodes of rhinitis. These peculiarities are insufficiently pronounced to single out a population at risk that might benefit from detection of the bacterium.
authors.affiliation: Clinique médicale infantile, Centre hospitalier régional et universitaire, Grenoble.
authors.forename: P
authors.initials: P
authors.lastname: François
authors.forename: P
authors.initials: P
authors.lastname: Hirtz
authors.forename: D
authors.initials: D
authors.lastname: Rouhan
authors.forename: M
authors.initials: M
authors.lastname: Favier
authors.forename: B
authors.initials: B
authors.lastname: Gratacap
authors.forename: A
authors.initials: A
authors.lastname: Beaudoing
mesh_terms: D000293:Adolescent; D000328:Adult; D002582:Cervix Mucus / Q000382:microbiology; D002690:Chlamydia Infections / Q000635:transmission*; D002692:Chlamydia trachomatis; D003228:Conjunctiva / Q000382:microbiology; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007231:Infant, Newborn; D009305:Nasopharynx / Q000382:microbiology; D011247:Pregnancy; D011446:Prospective Studies; D012698:Serologic Tests
vernacular_title: Transmission materno-infantile de Chlamydia trachomatis. Enquête prospective chez 168 parturientes.