title: Successful chemical cholecystectomy: a laparoscopic guided technique.
abstract: A laparoscopic guided technique of percutaneous chemical destruction of the gall bladder is described. The procedure entails the creation of a percutaneous access cholecystostomy for stone removal/fragmentation. After endoscopic occlusion of the cystic duct, the alkali corrosive, sodium carbonate was instilled into the gall bladder for 10-15 minutes. The treatment was applied in 11 animals with three deaths because of technical mishaps and eight survivors, in five of which a histologically confirmed complete destruction of the gall bladder (chemical cholecystectomy) was achieved without damage to the rest of the biliary tract or liver parenchyma.
authors.affiliation: Department of Surgery, Ninewells Hospital and Medical School, University of Dundee, Scotland.
authors.forename: A
authors.initials: A
authors.lastname: Cuschieri
authors.forename: A A
authors.initials: AA
authors.lastname: Abd el Ghany
authors.forename: M P
authors.initials: MP
authors.lastname: Holley
mesh_terms: D000818:Animals; D002254:Carbonates / Q000008:administration & dosage*; D002761:Cholangitis / Q000139:chemically induced; D002763:Cholecystectomy / Q000379:methods; D002769:Cholelithiasis / Q000628:therapy*; D004195:Disease Models, Animal; D005704:Gallbladder / Q000187:drug effects / Q000473:pathology; D010535:Laparoscopy; D009336:Necrosis; D013552:Swine
chemical_list: D002254:Carbonates; C005686:sodium carbonate