title: Cure and improvement of renovascular hypertension after percutaneous transluminal angioplasty of renal artery stenosis.
abstract: In the present study we report our long-term experience in 82 patients with renovascular hypertension (48 with atherosclerotic stenosis, 34 with fibromuscular dysplasia) who were followed up for a mean observation period of 23.6 months after percutaneous transluminal angioplasty (PTA) of renal artery stenosis. Our results show a highly significant decrease in mean systolic and diastolic blood pressure. Cure rates were slightly higher in patients with fibromuscular dysplasia (41% cured, 47% improved) than in those with atherosclerosis (23% cured, 54% improved). Kidney function significantly improved in patients with cure, remained stable in those with improvement and worsened in cases classified as unimproved. These results document the good long-term effect of PTA on blood pressure and kidney function in patients with renal artery stenosis.
authors.affiliation: Department of Internal Medicine, University Hospital, Zurich, Switzerland.
authors.forename: P
authors.initials: P
authors.lastname: Greminger
authors.forename: A
authors.initials: A
authors.lastname: Steiner
authors.forename: E
authors.initials: E
authors.lastname: Schneider
authors.forename: U
authors.initials: U
authors.lastname: Kuhlmann
authors.forename: J
authors.initials: J
authors.lastname: Steurer
authors.forename: W
authors.initials: W
authors.lastname: Siegenthaler
authors.forename: W
authors.initials: W
authors.lastname: Vetter
mesh_terms: D000328:Adult; D000800:Angioplasty, Balloon / Q000009:adverse effects; D001161:Arteriosclerosis / Q000150:complications / Q000628:therapy; D001794:Blood Pressure; D005260:Female; D005352:Fibromuscular Dysplasia / Q000150:complications / Q000628:therapy; D006801:Humans; D006978:Hypertension, Renovascular / Q000209:etiology / Q000503:physiopathology*; D007668:Kidney / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012078:Renal Artery Obstruction / Q000150:complications / Q000628:therapy*