title: Proteinuria and haematuria are frequently present in patients with lung cancer.
abstract: The aim of the study was to ascertain whether there is an increased occurrence of proteinuria and/or haematuria among lung cancer patients. As a control group we selected patients with bronchial asthma treated at the same hospital and during the same period as the lung cancer patients. The study comprised a retrospective part, where observations were made at two hospitals on 166 and 284 lung cancer patients. Proteinuria was observed in 9% and 13% and haematuria in 5% and 9% of these patients. The prevalences were significantly greater than among the asthmatic patients. This result prompted a prospective case-control study involving 150 consecutive patients with lung cancer and asthma, respectively. Twelve patients in the cancer group and one asthmatic patient had a daily urine protein excretion exceeding 100 mg (P less than 0.004); haematuria was noted in 14 and one, respectively (P less than 0.002). We conclude that the occurrence of proteinuria and haematuria is unexpectedly increased among patients with lung cancer.
authors.affiliation: Department of Internal Medicine, University Central Hospital, Tampere, Finland.
authors.forename: H
authors.initials: H
authors.lastname: Puolijoki
authors.forename: J
authors.initials: J
authors.lastname: Mustonen
authors.forename: E
authors.initials: E
authors.lastname: Pettersson
authors.forename: A
authors.initials: A
authors.lastname: Pasternack
authors.forename: A
authors.initials: A
authors.lastname: Lahdensuo
mesh_terms: D000368:Aged; D001249:Asthma / Q000150:complications; D016022:Case-Control Studies; D005260:Female; D006417:Hematuria / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D011507:Proteinuria / Q000453:epidemiology / Q000209:etiology*; D012189:Retrospective Studies