Reduction of the vein graft occlusion rate after coronary artery bypass surgery by treatment with a thromboxane receptor antagonist.
The early occlusion rate of vein grafts after coronary artery bypass surgery was reduced to 3.1% by treatment with a selective thromboxane receptor antagonist. The increased bleeding tendency caused by the substance led to a non-significant increase in blood transfusions.
Hacker
R W
RW
Herz- und Gefässklinik, Bad Neustadt/Saale.
Torka
M
M
Yükseltan
I
I
Pohlmann
V
V
Meier
P
P
Zimmermann
T
T
Etti
H
H
D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001026:Coronary Artery Bypass; D004311:Double-Blind Method; D006083:Graft Occlusion, Vascular / Q000517:prevention & control*; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D011982:Receptors, Prostaglandin / Q000378:metabolism; D017482:Receptors, Thromboxane; D013449:Sulfonamides / Q000627:therapeutic use
D000889:Anti-Arrhythmia Agents; D011982:Receptors, Prostaglandin; D017482:Receptors, Thromboxane; D013449:Sulfonamides; C040624:sulotroban