title: Importance of balloon size in coronary angioplasty.
abstract: The effect of balloon size on the success of coronary angioplasty was studied to develop quantitative criteria for optimal selection of balloon size. Coronary dimensions of 165 stenotic lesions were measured by computer-assisted cinevideodensitometry in 120 patients who had undergone angioplasty with a balloon selected by visual estimates. Cross-sectional areas and diameters of normal and stenotic arterial segments were measured before and after angioplasty by a previously validated cinevideodensitometric technique. The diameter of the inflated balloon compared with that of the normal arterial segment was expressed as a ratio for sizing balloons. Oversized balloons with a ratio greater than 1.3 (n = 35) caused a high (37%) incidence of dissection, with three severely compromised arterial lumens. Undersized balloons with a ratio less than 0.9 (n = 29) often resulted in significant (greater than 50% diameter stenosis) residual stenotic lesions (21%) and a significantly (p less than 0.05) higher rate of repeat angioplasty for restenosis. Selection of balloon sizes with ratios in the 0.9 to 1.3 range (n = 101) resulted in a low (4%) incidence of dissection with few patients (3%) having significant residual stenosis. Mean residual stenosis (percent diameter reduction) was most severe for undersized (35.0 +/- 18%) or oversized (23.1 +/- 19%) balloons and least severe for balloons with a ratio of 0.9 to 1.3 (18.7 +/- 14%) (p less than 0.001). Repeat angioplasty for restenosis was more frequently required (p less than 0.05) for lesions dilated with undersized balloons. Thus, selection of angioplasty balloons that approximate or slightly exceed the diameter of the normal arterial diameter yields optimal angiographic results with minimal dissections and minimal residual stenotic lesions.
authors.affiliation: Department of Medicine, College of Physicians and Surgeons, Columbia University.
authors.forename: A B
authors.initials: AB
authors.lastname: Nichols
authors.forename: R
authors.initials: R
authors.lastname: Smith
authors.forename: A D
authors.initials: AD
authors.lastname: Berke
authors.forename: R A
authors.initials: RA
authors.lastname: Shlofmitz
authors.forename: E R
authors.initials: ER
authors.lastname: Powers
mesh_terms: D000800:Angioplasty, Balloon / Q000295:instrumentation*; D002932:Cineangiography; D003251:Constriction, Pathologic / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D003720:Densitometry; D003936:Diagnosis, Computer-Assisted; D006801:Humans