title: Therapy in premenopausal women with advanced, oestrogen positive or/and progesterone positive breast cancer: surgical oophorectomy versus the LHRH analogue, Zoladex.
abstract: The basis and design of a trial that will compare surgical oophorectomy with the LHRH analogue, Zoladex, in the treatment of premenopausal women with advanced, oestrogen receptor-positive or progesterone receptor-positive breast cancer, is described.
authors.affiliation: Southwest Oncology Group, New England Medical Center, Boston, Mass.
authors.forename: N J
authors.initials: NJ
authors.lastname: Robert
authors.forename: W S
authors.initials: WS
authors.lastname: Dalton
authors.forename: C K
authors.initials: CK
authors.lastname: Osborne
authors.forename: M
authors.initials: M
authors.lastname: Abeloff
mesh_terms: D001943:Breast Neoplasms / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery / Q000628:therapy*; D002064:Buserelin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D017273:Goserelin; D006801:Humans; D010052:Ovariectomy; D011960:Receptors, Estrogen / Q000502:physiology*; D011980:Receptors, Progesterone / Q000502:physiology*
chemical_list: D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D017273:Goserelin; D002064:Buserelin