title: [Stereostructure-activity relation of morphinics. Topology of the mu receptor and nature of the opioid pharmacophore].
abstract: The perspective of this essay is to issue a stereostructure-activity relationship analysis of opioid compounds in terms of the topology of P et T subsites of the mu receptor. Emphasis is put on the dichotomic nature of the opioid pharmacophore made of pharmacons and tensors.
authors.forename: J
authors.initials: J
authors.lastname: Poupaert
mesh_terms: D000818:Animals; D006801:Humans; D008968:Molecular Conformation; D009022:Morphine Derivatives / Q000494:pharmacology*; D011957:Receptors, Opioid / Q000378:metabolism*; D017450:Receptors, Opioid, mu; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D009022:Morphine Derivatives; D011957:Receptors, Opioid; D017450:Receptors, Opioid, mu
vernacular_title: Relation stéréostructure-activité des morphiniques. Topologie du récepteur mu et nature du pharmacophore opioïde.