Adenovirus infection retards ribosomal RNA processing.
Eight hours after infection of KB cells with adenovirus type 12, the rate of conversion from the 32S ribosomal RNA (rRNA) precursor to mature 28S and 5.8S rRNA decreased. An additional RNA species was detected, which appears to be novel, on the basis of its estimated size (about 6.5 kilobases) and its high level of radiolabeling early after infection at low multiplicity.
Lawler
S H
SH
Department of Pathology, St. Louis University School of Medicine, Missouri 63104.
Jones
R W
RW
Eliceiri
B P
BP
Eliceiri
G L
GL
D000257:Adenoviridae Infections / Q000235:genetics*; D000818:Animals; D002460:Cell Line; D005786:Gene Expression Regulation; D012335:RNA, Ribosomal / Q000378:metabolism*; D012339:RNA, Ribosomal, 28S / Q000378:metabolism*; D012340:RNA, Ribosomal, 5.8S / Q000378:metabolism; D012342:RNA, Small Nuclear / Q000378:metabolism
D012335:RNA, Ribosomal; D012339:RNA, Ribosomal, 28S; D012340:RNA, Ribosomal, 5.8S; D012342:RNA, Small Nuclear