title: Isolation of microorganisms capable of degrading isoquinoline under aerobic conditions.
abstract: Isoquinoline-degrading microbial cultures were isolated from oil- and creosote-contaminated soils. The establishment of initial enrichment cultures required the use of emulsified isoquinoline. Once growth on isoquinoline was established, isoquinoline emulsification was no longer required for utilization of isoquinoline as the sole source of carbon and nitrogen by these cultures. An isoquinoline-degrading Acinetobacter strain was isolated from one of the enrichment cultures. The degradation of isoquinoline was accompanied by the accumulation of a red cell-associated pigment and of 1-hydroxyisoquinoline, which was further degraded to unknown intermediary ring-cleavage products and carbon dioxide.
authors.affiliation: Department of Biology, University of Louisville, Kentucky 40292.
authors.forename: J
authors.initials: J
authors.lastname: Aislabie
authors.forename: S
authors.initials: S
authors.lastname: Rothenburger
authors.forename: R M
authors.initials: RM
authors.lastname: Atlas
mesh_terms: D000150:Acinetobacter / Q000254:growth & development / Q000302:isolation & purification* / Q000378:metabolism; D001419:Bacteria / Q000254:growth & development / Q000302:isolation & purification* / Q000378:metabolism; D001673:Biodegradation, Environmental; D002245:Carbon Dioxide / Q000378:metabolism; D007546:Isoquinolines / Q000378:metabolism*; D012988:Soil Microbiology; D012989:Soil Pollutants / Q000378:metabolism
chemical_list: D007546:Isoquinolines; D012989:Soil Pollutants; D002245:Carbon Dioxide; C039109:isoquinoline