Aplastic crisis in occult hereditary spherocytosis caused by human parvovirus (HPV B19).
We have reported a case of aplastic crisis occurring in an 11-year-old black boy with occult hereditary spherocytosis. An etiologic diagnosis of human parvovirus (HPV) B19 infection was confirmed serologically. The Coulter Model S + IV proved useful for both diagnosis and treatment monitoring through serial histograms. The relationship of HPV infection and aplastic crisis is discussed.
Rappaport
E S
ES
Department of Pathology, Scott and White Clinic, Scott and White Memorial Hospital, Temple, TX 76508.
Quick
G
G
Ransom
D
D
Helbert
B
B
Frankel
L S
LS
D000208:Acute Disease; D000741:Anemia, Aplastic / Q000209:etiology*; D001803:Blood Transfusion; D001853:Bone Marrow / Q000473:pathology; D002648:Child; D004912:Erythrocytes / Q000473:pathology; D004920:Erythropoiesis; D006801:Humans; D008297:Male; D010322:Parvoviridae Infections / Q000097:blood / Q000150:complications*; D013103:Spherocytosis, Hereditary / Q000097:blood*