[The effect of anti-T sera on the natural killer activity of the splenocytes in C3HA mice at different times after the transplantation of hepatoma 22a cells].
Suspension of splenocytes of control C3HA mice and mice examined early after transplantation of mouse hepatoma 22a cells were fractionated by treatment with anti-T-sera (anti-thymocytes, antibrain and anti-suppressor-T-cells). This treatment leads to various changes in NK-activity due to elimination of different subpopulations of T-lymphocytes. This variability may be associated with the presence of two or more types of suppressor cells able to influence the NK-cells directly or by means of other immunocompetent cells.
Filatova
N A
NA
Malygin
A M
AM
Goriunova
L B
LB
Fel'
V Ia
VIa
D000818:Animals; D000961:Antilymphocyte Serum / Q000494:pharmacology*; D001921:Brain / Q000276:immunology; D007694:Killer Cells, Natural / Q000187:drug effects* / Q000276:immunology; D008114:Liver Neoplasms, Experimental / Q000276:immunology*; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H / Q000276:immunology*; D009368:Neoplasm Transplantation; D013154:Spleen / Q000187:drug effects* / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology; D013997:Time Factors
D000961:Antilymphocyte Serum
Vliianie anti-T-syvorotok na estestvennuiu killernuiu aktivnost' splenotsitov mysheĭ C3HA v rannie sroki posle transplantatsii kletok gepatomy 22a.