Fluoropyrimidine metabolism in human head and neck cancer xenografts and murine colon tumors.
Laurensse
E J
EJ
Department of Oncology, Free University Hospital, Amsterdam, the Netherlands.
Braakhuis
B J
BJ
Pinedo
H M
HM
Peters
G J
GJ
D000818:Animals; D003110:Colonic Neoplasms / Q000378:metabolism*; D004354:Drug Screening Assays, Antitumor / Q000379:methods; D005467:Floxuridine / Q000378:metabolism* / Q000493:pharmacokinetics; D005472:Fluorouracil / Q000378:metabolism* / Q000493:pharmacokinetics; D006258:Head and Neck Neoplasms / Q000378:metabolism*; D006801:Humans; D051379:Mice; D009368:Neoplasm Transplantation; D009962:Orotate Phosphoribosyltransferase / Q000378:metabolism*; D010430:Pentosyltransferases / Q000378:metabolism*; D057845:Pyrimidine Phosphorylases; D014407:Tumor Cells, Cultured / Q000378:metabolism
D005467:Floxuridine; D010430:Pentosyltransferases; D057845:Pyrimidine Phosphorylases; D009962:Orotate Phosphoribosyltransferase; D005472:Fluorouracil; C025034:doxifluridine