[Bone marrow aplasia associated with ticlopidine treatment in a patient with idiopathic hypothyroidism].
A new case of severe bone-marrow aplasia due to Ticlopidine therapy is described. On the basis also of immunologic findings, the drug seems to be the cause of the hematologic syndrome. The presence of an idiopathic hypothyroidism may have favored the immune mediated reaction to the drug.
Pioda
G B
GB
Del Favero
A
A
Rambotti
P
P
D000741:Anemia, Aplastic / Q000139:chemically induced* / Q000276:immunology; D002994:Clofibrate / Q000031:analogs & derivatives; D005260:Female; D006801:Humans; D000960:Hypolipidemic Agents; D007037:Hypothyroidism / Q000150:complications*; D008213:Lymphocyte Activation; D008875:Middle Aged; D013988:Ticlopidine / Q000009:adverse effects*
D000960:Hypolipidemic Agents; D002994:Clofibrate; C003278:simfibrate; D013988:Ticlopidine
Aplasia midollare associata a trattamento con ticlopidina in soggetto con ipotiroidismo idiopatico.