Structure and dynamics of a lipoic acid-arsenical adduct.
The lipoic acid-phenyldichloroarsine adduct was prepared in methanol, and the structure and molecular motions of this adduct were studied. The results showed that a six-membered heteroatom adduct was formed. One-dimensional and two-dimensional NMR spectroscopy was used to confirm the structure and assign some of the resonances in the proton and carbon spectra. Spin-lattice relaxation times of the various carbon atoms indicated that the overall molecular reorientation time (tau R) of the molecule is 0.02 ns at 30 degrees C. An Arrhenius plot of the data showed that the activation energy (Ea) for molecular tumbling is 13.4 kJ/mol.
Dill
K
K
Department of Chemistry, Clemson University, South Carolina 29634.
Adams
E R
ER
O'Connor
R J
RJ
McGown
E L
EL
D001152:Arsenicals / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D013696:Temperature; D008063:Thioctic Acid / Q000737:chemistry*
D001152:Arsenicals; C053663:phenyldichloroarsine; D008063:Thioctic Acid