title: Seroprevalence of Trypanosoma cruzi infection among unskilled urban workers in central Brazil.
abstract: A cross-sectional survey of the prevalence of Trypanosoma cruzi infection was carried out among urban unskilled workers in an endemic area in central Brazil as part of a study to assess the health impact of Chagas disease and to identify risk factors for the evolution of cardiopathy. Blood samples from 5425 male and female workers, aged 15-61 years, from 5 public institutions, were screened by indirect immunofluorescence, enzyme-linked immunosorbent assay and indirect haemagglutination for antibodies to T. cruzi. Seroprevalence varied from 8.8% to 15.6% in the different institutions and increase with age up to 55 years. More stable jobs were associated with lower seroprevalence. Migrants from São Paulo and Minas Gerais presented higher prevalence and a relative risk associated with seropositivity in relation to workers from Goiás of 2.2 (95% confidence limits, 1.4-3.5) and 1.9 (1.6-2.3), respectively.
authors.affiliation: Institute of Tropical Pathology and Public Health, University of Goiás, Goiânia-GO, Brazil.
authors.forename: F
authors.initials: F
authors.lastname: Zicker
authors.forename: R M
authors.initials: RM
authors.lastname: Oliveira
authors.forename: A O
authors.initials: AO
authors.lastname: Luquetti
authors.forename: O S
authors.initials: OS
authors.lastname: Oliveira
authors.forename: P G
authors.initials: PG
authors.lastname: Smith
mesh_terms: D000293:Adolescent; D000328:Adult; D000913:Antibodies, Protozoan / Q000032:analysis; D001938:Brazil / Q000453:epidemiology; D014355:Chagas Disease / Q000453:epidemiology* / Q000276:immunology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009790:Occupations; D012307:Risk Factors; D012959:Socioeconomic Factors; D014171:Transients and Migrants; D014505:Urban Population
chemical_list: D000913:Antibodies, Protozoan