[Hemodynamic vertebrobasilar insufficiency demonstrated by chronic oligemic cerebral flow and cerebellar ataxia: two new concepts].
We propose in the paper of the concept of nuclear hemodynamic vertebrobasilar insufficiency, defined as an oligemic blood flow lower than 35 ml/100 g/min. in the brain stem-cerebellum zone, when using the method of inhalation of 133Xe. In 15 patients, the neurophysiologic manifestations included intermittent symptoms. We describe here permanent neurophysiologic motor disturbances: extrapyramidal Dopa sensitive syndrome (2/15), chronic cerebellar ataxia (12/15), often associated with cerebellar atrophy (8/12). The concept of chronic oligemic cerebellar ataxia, corresponding to selective neuronal death and/or neurochemical failure, is proposed.
Trouillas
P
P
Service de Neurologie B, Faculté Alexis-Carrel, Hôpital neurologique, Lyon.
Philippon
B
B
Nighoghossian
N
N
D000280:Administration, Inhalation; D002524:Cerebellar Ataxia / Q000503:physiopathology*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D002908:Chronic Disease; D006439:Hemodynamics; D006801:Humans; D014715:Vertebrobasilar Insufficiency / Q000503:physiopathology*; D014980:Xenon Radioisotopes / Q000008:administration & dosage
D014980:Xenon Radioisotopes
Insuffisance vertébro-basilaire hémodynamique démontrée par les débits cérébraux et ataxie cérébelleuse oligémique chronique: deux nouveaux concepts.