[Experimental research on the genotoxicity of various root canal antiseptics in the SOS chromotest].
The genotoxicity of the endodontic antiseptics chlorhexidine digluconate, chloramine and sodium hypochlorite was determined by SOS chromotest using Bioscreen Analyzer Systems (Labsystem OY). All antiseptics did not show a genotoxic effect. Chlorhexidine digluconate was the most efficient antimicrobial agent against E. coli PQ 37.
Klimm
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Janz
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Gabert
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A
D000891:Anti-Infective Agents, Local; D004260:DNA Repair / Q000187:drug effects*; D004269:DNA, Bacterial / Q000187:drug effects*; D004926:Escherichia coli / Q000187:drug effects*; D009152:Mutagenicity Tests / Q000295:instrumentation / Q000379:methods; D012388:Root Canal Irrigants / Q000633:toxicity*; D013014:SOS Response, Genetics / Q000187:drug effects*
D000891:Anti-Infective Agents, Local; D004269:DNA, Bacterial; D012388:Root Canal Irrigants
Experimentelle Untersuchungen zur Genotoxizität verschiedener Wurzelkanalantiseptika im SOS-Chromotest.