title: Detection of specific IgG and IgA antibodies to Chlamydia trachomatis in women with salpingitis confirmed by laparoscopy.
abstract: The sera from 12 consecutive symptomatic women with laparoscopy-confirmed salpingitis were screened for the presence of specific IgG and IgA antibodies to Chlamydia trachomatis by a single antigen (L-2) immunoperoxidase assay. All women were found to have IgG and IgA antibodies to C trachomatis. Six women had positive endocervical cultures for C trachomatis, and one of these had positive cultures from the conjunctiva and fallopian tubes. Serum chlamydial IgA antibodies may serve as markers for active infection with C trachomatis regardless of whether organisms can be identified by culture or direct fluorescent antibody techniques from endocervical or fallopian tube samples.
authors.forename: N G
authors.initials: NG
authors.lastname: Osborne
authors.forename: Y
authors.initials: Y
authors.lastname: Hecht
authors.forename: J
authors.initials: J
authors.lastname: Gorsline
authors.forename: B A
authors.initials: BA
authors.lastname: Forbes
authors.forename: F
authors.initials: F
authors.lastname: Morgenstern
authors.forename: J
authors.initials: J
authors.lastname: Winkelman
mesh_terms: D000907:Antibodies, Bacterial / Q000032:analysis; D002690:Chlamydia Infections / Q000276:immunology*; D002692:Chlamydia trachomatis / Q000276:immunology*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D010535:Laparoscopy; D012488:Salpingitis / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D007074:Immunoglobulin G