title: [Secondary diseases of the heart muscle and their differential diagnosis in childhood].
abstract: Possible causes of specific cardiac muscle disease, diagnosis, follow-up and the therapeutic management are discussed on the basis of a series of cases. 8 out of 30 patients who showed the clinical picture of dilative cardiomyopathy (DCM) were found to have a specific cardiac muscle disease. 4 patients had DCM following adriamycin therapy. Fibromuscular dysplasia with renal hypertension, thalassaemia major with secondary haemosiderosis, long-overlooked and untreated athyroidism each caused one case of dilative specific cardiac muscle disease. Once DCM was preceded by the Kawasaki syndrome for over 2 years. Amongst 47 patients with hypertrophic cardiomyopathy there were two children who had undergone ACTH treatment, 6 children born of diabetic mothers, 4 cases of Pompe's disease, and one patient with hypothyroidism resulting in reversible hypertrophy of the cardiac muscle. Different neurodegenerative diseases were associated with cardiac muscle disease in 4 cases, partly dictating the clinical course. Extremely rare was the development over 6 years of cardiac hypertrophy following a burns injury.
authors.affiliation: Abteilung für pädiatrische Kardiologie, Universitäts-Kinderklinik Tübingen, Bundesrepublik Deutschland.
authors.forename: L
authors.initials: L
authors.lastname: Sieverding
authors.forename: A A
authors.initials: AA
authors.lastname: Schmaltz
authors.forename: D
authors.initials: D
authors.lastname: Hassberg
authors.forename: J
authors.initials: J
authors.lastname: Apitz
authors.forename: W
authors.initials: W
authors.lastname: Hort
mesh_terms: D000293:Adolescent; D000324:Adrenocorticotropic Hormone / Q000009:adverse effects; D009202:Cardiomyopathies / Q000139:chemically induced / Q000209:etiology*; D002311:Cardiomyopathy, Dilated / Q000209:etiology; D002312:Cardiomyopathy, Hypertrophic / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004317:Doxorubicin / Q000009:adverse effects; D004452:Echocardiography; D006801:Humans; D007223:Infant; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D004317:Doxorubicin; D000324:Adrenocorticotropic Hormone
vernacular_title: Sekundäre Herzmuskelerkrankungen und ihre Differentialdiagnose im Kindesalter.