Ovum donation by sisters in ovarian failure: simplified priming and early withdrawal of exogenous support.
Two cases of successful pregnancy and delivery by patients with ovarian failure are reported. In both cases ova were donated by the sister of the patient. A high degree of success (two pregnancies in three attempts) is discussed, as is the significance of simplified pretransfer "priming" and very early withdrawal of exogenous hormonal support.
Rosenberg
S M
SM
Richmond Center for Fertility and Endocrinology, Ltd., Richmond, Virginia.
East
J M
JM
Wood
S C
SC
Crain
J L
JL
D000077713:17 alpha-Hydroxyprogesterone Caproate; D000328:Adult; D004624:Embryo Transfer; D004958:Estradiol / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D006801:Humans; D006908:Hydroxyprogesterones / Q000008:administration & dosage / Q000494:pharmacology; D016729:Leuprolide; D008593:Menopause; D008594:Menopause, Premature; D008597:Menstrual Cycle / Q000187:drug effects*; D006080:Ovarian Follicle / Q000187:drug effects; D011247:Pregnancy; D011374:Progesterone / Q000008:administration & dosage / Q000494:pharmacology*; D014019:Tissue Donors
D006908:Hydroxyprogesterones; D000077713:17 alpha-Hydroxyprogesterone Caproate; D007987:Gonadotropin-Releasing Hormone; D011374:Progesterone; D004958:Estradiol; D016729:Leuprolide