Intravitreal ganciclovir in CMV retinitis: case report.
A case is reported of a 35-year-old male with established acquired immune deficiency syndrome who developed cytomegalovirus retinitis. When intravenous treatment with ganciclovir had to be withdrawn because of toxicity, one eye was treated successfully by intravitreal injections of the drug. After 15 weeks of intravitreal treatment this eye developed endophthalmitis.
Harris
M L
ML
St Stephen's Hospital, London.
Mathalone
M B
MB
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000212:Acyclovir / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000328:Adult; D000998:Antiviral Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D003586:Cytomegalovirus Infections / Q000188:drug therapy*; D015774:Ganciclovir; D006801:Humans; D007267:Injections; D008297:Male; D012173:Retinitis / Q000188:drug therapy* / Q000209:etiology; D014822:Vitreous Body
D000998:Antiviral Agents; D015774:Ganciclovir; D000212:Acyclovir