Prognostic indicators for failure of surveillance management of stage I non-seminomatous germ cell tumours.
Fifty-three patients presenting with non-seminomatous germ cell tumours (NSGCT) of the testis were examined. Particular interest was directed towards the association of several morphological features of the primary tumour with metastatic disease, either at presentation or later in the course of the tumour. It is apparent from this study that the presence of vascular invasion in the primary tumour, high T stage (advanced local disease) and the presence of choriocarcinoma are poor prognostic signs in NSGCT. In such tumours presenting as clinical stage I, surveillance management may not be appropriate because of the high rate of relapse.
Costello
A J
AJ
Department of Urology, St Vincent's Hospital, Fitzroy, Victoria, Australia.
Mortensen
P H
PH
Stillwell
R G
RG
D000328:Adult; D002822:Choriocarcinoma / Q000098:blood supply / Q000473:pathology*; D004407:Dysgerminoma / Q000098:blood supply / Q000473:pathology*; D005069:Evaluation Studies as Topic; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D009373:Neoplasms, Germ Cell and Embryonal / Q000098:blood supply / Q000473:pathology; D009919:Orchiectomy; D011379:Prognosis; D012189:Retrospective Studies; D013736:Testicular Neoplasms / Q000098:blood supply / Q000473:pathology*; D013997:Time Factors