Current and future trends in acute pain management.
The rationale for improving analgesic therapy is presented. After reviewing the role of drug pharmacokinetic and pharmacodynamic variability in determining the quality of pain relief, newer developments in acute pain management are described: newer opioid and nonopioid analgesic drugs; alternative drug delivery systems; nonpharmacologic approaches, use of combination analgesic therapy. Finally, several possible future research trends in acute pain management are discussed.
White
P F
PF
Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri.
D000208:Acute Disease; D000700:Analgesics / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D010146:Pain / Q000188:drug therapy; D059408:Pain Management
D000700:Analgesics