[Thermo-regulated expression of the htpR gene under the control of the PR-promotor of bacteriophage lambda induces supersynthesis of heat shock proteins].
The mechanisms of induction of heat shock protein synthesis in E. coli have been studied. For this purpose plasmids in which htpR gene expression is controlled by the PR-promoter of bacteriophage lambda and by the Trp-promoter have been constructed. An effective induction of heat shock proteins requires both an increased content of htpR protein and additional cofactors formed in the cell under heat shock conditions.
Kiselev
V I
VI
Tarasova
I M
IM
Shchepetov
M E
ME
Grabovetskiĭ
V V
VV
D001345:Autoradiography; D010582:Bacteriophage lambda / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics* / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D015967:Gene Expression Regulation, Viral; D006360:Heat-Shock Proteins / Q000096:biosynthesis*; D010957:Plasmids; D011401:Promoter Regions, Genetic
D006360:Heat-Shock Proteins
Termoreguliruemaia ékspressiia gena htpR pod kontrolem PR-promotora bakteriofaga lambda indutsiruet sverkhsintez belkov teplovogo shoka.