Detailed morphology of the tensor tympani muscle of the rat. An integrated light microscopical, morphometrical, histochemical, immunohistochemical and electron microscopical study in relation to function.
The gross anatomy, microscopical anatomy, morphometry, enzyme histochemistry, immunohistochemistry and electron microscopy of the tensor tympani muscle of the rat was studied. The aim of the study was to create an integrated insight into the morphology of the muscle and to discuss functional implications. The tensor tympani muscle of the rat is an atypical muscle. It is a small muscle composed of very small muscle fibres with a complex microscopical and submicroscopical architecture. Histochemically the muscle consists mainly of fast oxidative glycolytic fibres, but discrepancies are found when anti-heavy chain myosin antibodies are used for fibre typing. Different adult heavy chain myosin isotypes coexist in one single muscle fibre. The electron microscopical study shows that bundles of myofilaments branch and interconnect with other bundles of myofilaments. The findings suggest that the muscle is able to contract fast and is fatigue-resistant. Both features seem to suggest that the muscle has a function in protecting the inner ear against noise damage.
van den Berge
H
H
Department of Otorhinolaryngology, University of Maastricht, The Netherlands.
Wirtz
P
P
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D005993:Glycerolphosphate Dehydrogenase / Q000378:metabolism; D006651:Histocytochemistry; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D009132:Muscles / Q000166:cytology* / Q000201:enzymology / Q000502:physiology; D009218:Myosins / Q000378:metabolism; D051381:Rats; D011917:Rats, Inbred Lew; D013385:Succinate Dehydrogenase / Q000378:metabolism; D013719:Tensor Tympani / Q000033:anatomy & histology* / Q000378:metabolism / Q000648:ultrastructure; D014432:Tympanic Membrane / Q000033:anatomy & histology*
D005993:Glycerolphosphate Dehydrogenase; D013385:Succinate Dehydrogenase; D000251:Adenosine Triphosphatases; D009218:Myosins