title: Frequency and molecular types of deletional alpha-thalassemia in Egypt.
abstract: The frequency of deletional alpha-thalassemia in the Egyptian population was estimated at 0.08 by DNA analysis of a newborn random sample. No alpha 0 determinants were found. The most frequent alpha+ determinant was the -alpha 3.7 type I in association with the medium allele at inter-zeta HVR. The -alpha 4.2 and alpha alpha alpha anti 3.7 arrangements were found at very low frequencies.
authors.affiliation: Dipartimento di Biologia, Università Tor Vergata, La Romanina, Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Novelletto
authors.forename: M
authors.initials: M
authors.lastname: Hafez
authors.forename: A
authors.initials: A
authors.lastname: Di Rienzo
authors.forename: L
authors.initials: L
authors.lastname: Felicetti
authors.forename: G
authors.initials: G
authors.lastname: Deidda
authors.forename: Z
authors.initials: Z
authors.lastname: el Morsi
authors.forename: Y
authors.initials: Y
authors.lastname: al-Tonbary
authors.forename: M
authors.initials: M
authors.lastname: el-Ziny
authors.forename: N
authors.initials: N
authors.lastname: Abd-el-Gelil
authors.forename: L
authors.initials: L
authors.lastname: Terrenato
mesh_terms: D002872:Chromosome Deletion; D004262:DNA Restriction Enzymes; D004534:Egypt; D005914:Globins / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D005810:Multigene Family; D013789:Thalassemia / Q000453:epidemiology / Q000235:genetics*
chemical_list: D005914:Globins; D004262:DNA Restriction Enzymes