title: Usefulness of serology for the evaluation of Trypanosoma cruzi transmission in endemic areas of Chagas' disease.
abstract: Thirteen communities from 7 Argentinian provinces were selected for the evaluation of serology as an indicator of transmission of Chagas disease. Of the communities appraised, 6 did not have a history of previous treatment with insecticides and 7 had received sporadic or continuous insecticide treatment. The inhabitants of 20% of the houses of each locality were studied by serology. The samples were obtained by finger pricking and 50 microliters of blood were mixed with 15 microliter of 50% glycerine solution in tissue culture media to be assayed by Indirect Hemagglutination and Indirect Immunofluorescence tests. In untreated areas, the prevalence of infection in infants 0-4 years old was 17.5%, reaching to over 22% for the 5-9 year old group, and to 33.3% in 10-14 year old individuals. The prevalence in treated and surveyed areas was 2.6% in 0-4 year old children, 5.4% in 5-9 year old and 6.2% in 10-14 year old youngsters. The differences between both areas were statistically significant (p less than 0.005). This study favors serology as a valid indicator for the evaluation of transmission of Chagas disease in rural areas.
authors.forename: R
authors.initials: R
authors.lastname: Chuit
authors.forename: E
authors.initials: E
authors.lastname: Subias
authors.forename: A C
authors.initials: AC
authors.lastname: Pérez
authors.forename: I
authors.initials: I
authors.lastname: Paulone
authors.forename: C
authors.initials: C
authors.lastname: Wisnivesky-Colli
authors.forename: E L
authors.initials: EL
authors.lastname: Segura
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001118:Argentina / Q000453:epidemiology; D014355:Chagas Disease / Q000453:epidemiology* / Q000517:prevention & control; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007306:Insecticides; D008297:Male; D012423:Rural Health; D016036:Seroepidemiologic Studies
chemical_list: D007306:Insecticides