title: [The effect of metoclopramide on the acid and pepsin secretion of patients with chronic gastritis and peptic ulcer].
abstract: The authors studied the effect of single intakes of metoclopramide on the acid and pepsin secretion in patients with chronic gastritis and duodenal ulcer. Peroral intake of 20 mg of metoclopramide during histamine-stimulated gastric secretion resulted in a distinct reduction of H ions and an insignificant reduction of pepsin secretion. Cerucal-initiated inhibition of acidity is accompanied by reduction of potassium concentration.
authors.forename: E Ia
authors.initials: EIa
authors.lastname: Skliarov
authors.forename: V Z
authors.initials: VZ
authors.lastname: Makara
mesh_terms: D000328:Adult; D002908:Chronic Disease; D004341:Drug Evaluation; D005260:Female; D005744:Gastric Acid / Q000378:metabolism*; D005750:Gastric Juice / Q000187:drug effects / Q000378:metabolism; D005756:Gastritis / Q000188:drug therapy* / Q000503:physiopathology; D006632:Histamine; D006801:Humans; D008297:Male; D008787:Metoclopramide / Q000627:therapeutic use*; D008875:Middle Aged; D010434:Pepsin A / Q000378:metabolism*; D010437:Peptic Ulcer / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D006632:Histamine; D010434:Pepsin A; D008787:Metoclopramide
vernacular_title: Vliianie metoklopramida na kisloto- i pepsinovydelenie u bol'nykh khronicheskim gastritom i iazvennoĭ bolezni.