title: [Erythrocyte oxidative damage by myeloperoxidase. The protective action of serum proteins].
abstract: Influence of main serum proteins (albumin, immunoglobulin G) and proteins-antioxidants (ceruloplasmin, transferrin, superoxide dismutase) on the oxidative damage of erythrocytes by myeloperoxidase and hypochlorite was investigated. The proteins were determined to act as protectors and decrease the degree of hemoglobin oxidation, ceruloplasmin and albumin possessing the highest antioxidant activity.
authors.forename: N Iu
authors.initials: NIu
authors.lastname: Govorova
authors.forename: B P
authors.initials: BP
authors.lastname: Sharonov
authors.forename: S N
authors.initials: SN
authors.lastname: Lyzlova
mesh_terms: D000818:Animals; D000975:Antioxidants; D001798:Blood Proteins / Q000378:metabolism*; D002021:Buffers; D002384:Catalysis; D004305:Dose-Response Relationship, Drug; D004912:Erythrocytes / Q000187:drug effects* / Q000378:metabolism; D006801:Humans; D009504:Neutrophils / Q000201:enzymology; D010084:Oxidation-Reduction / Q000187:drug effects; D010100:Oxygen / Q000097:blood; D009195:Peroxidase / Q000302:isolation & purification / Q000494:pharmacology*; D013552:Swine
chemical_list: D000975:Antioxidants; D001798:Blood Proteins; D002021:Buffers; D009195:Peroxidase; D010100:Oxygen
vernacular_title: Okislitel'noe povrezhdenie éritrotsitov mieloperoksidazoĭ. Zashchitnoe deĭstvie syvorotochnykh belkov.