The effect of insulin on porcine adipose tissue lipogenesis.
1. This laboratory and others have not been able to demonstrate consistent insulin stimulation of glucose incorporation into lipid by porcine adipose tissue in vitro. 2. A multiplicity of tissue handling procedures, additions to the incubation medium, and pig size (age) did not allow the expression of a consistent and substantial insulin stimulation. 3. It is suggested that the twofold or greater stimulation of glucose metabolism observed occasionally in this laboratory results from pig genetics, husbandry, or seasonal effects.
Mersmann
H J
HJ
Roman L. Hruska US Meat Animal Research Center, US Department of Agriculture, Clay Center, NE 68933.
D000273:Adipose Tissue / Q000187:drug effects* / Q000378:metabolism; D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D002245:Carbon Dioxide / Q000378:metabolism; D003470:Culture Media; D005947:Glucose / Q000378:metabolism / Q000493:pharmacokinetics; D066298:In Vitro Techniques; D007328:Insulin / Q000494:pharmacology*; D008055:Lipids / Q000096:biosynthesis*; D008297:Male; D013552:Swine
D003470:Culture Media; D007328:Insulin; D008055:Lipids; D002245:Carbon Dioxide; D005947:Glucose