title: [The influence of previous infections on the development of experimental swine pleuropneumonia in specific pathogen free pigs].
abstract: This study was designed to determine in six-week old specific pathogen free pigs, the effect of previous experimental exposure to Mycoplasma hyopneumoniae and transmissible gastroenteritis virus on a challenge infection with Actinobacillus pleuropneumoniae. Pigs exposed simultaneously to M. hyopneumoniae and transmissible gastroenteritis virus appeared more resistant to challenge (one week later) with A. pleuropneumoniae. Four pigs out of a group of ten died following the challenge infection, compared to all ten pigs in the control group not submitted to previous infections. Clinical signs and lesions were also less severe in the previously infected group than in the control group. Pigs submitted to a single previous infection with M. hyopneumoniae only appeared to be less resistant to the challenge infection than pigs submitted to the dual previous infection with M. hyopneumoniae and the transmissible gastroenteritis virus. A correlation was found between the resistance of pigs to the challenge infection and their serum gammaglobulin levels.
authors.affiliation: Institut Armand-Frappier, Ville de Laval, Québec.
authors.forename: P
authors.initials: P
authors.lastname: Marois
authors.forename: E
authors.initials: E
authors.lastname: Di Franco
authors.forename: G
authors.initials: G
authors.lastname: Boulay
authors.forename: P
authors.initials: P
authors.lastname: Flipot
authors.forename: R
authors.initials: R
authors.lastname: Assaf
authors.forename: G
authors.initials: G
authors.lastname: Lamoureux
mesh_terms: D000189:Actinobacillus Infections / Q000276:immunology / Q000662:veterinary*; D000818:Animals; D001798:Blood Proteins / Q000378:metabolism; D005761:Gastroenteritis, Transmissible, of Swine / Q000276:immunology*; D007113:Immunity, Innate; D007074:Immunoglobulin G / Q000032:analysis; D009175:Mycoplasma Infections / Q000276:immunology / Q000662:veterinary*; D011001:Pleuropneumonia / Q000276:immunology / Q000662:veterinary*; D013047:Specific Pathogen-Free Organisms; D013552:Swine; D013553:Swine Diseases / Q000097:blood / Q000276:immunology*
chemical_list: D001798:Blood Proteins; D007074:Immunoglobulin G
vernacular_title: Influence d'infections préalables sur l'evolution de la pleuro-pneumonie porcine expérimentale chez des porcs exempts d'organismes pathogènes spécifiques.