Epstein-Barr virus induced thrombocytopenia treated with intravenous acyclovir and immunoglobulin.
We report infectious mononucleosis in a 15-year-old girl with severe thrombocytopenia (2 x 10(9)/l). Intravenous hydrocortisone in high doses for 4 days had no effect. When intravenous immunoglobulin and acyclovir were added an immediate response was noted with normalization of the thrombocyte count within 3 days.
Hugo
H
H
Department of Infectious Diseases, Central Hospital Ryhov, Jönköping, Sweden.
Linde
A
A
Abom
P E
PE
D000212:Acyclovir / Q000008:administration & dosage*; D000293:Adolescent; D004359:Drug Therapy, Combination; D005260:Female; D004854:Herpesvirus 4, Human; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage*; D007116:Immunization, Passive; D007136:Immunoglobulins / Q000008:administration & dosage*; D007244:Infectious Mononucleosis / Q000150:complications* / Q000628:therapy; D007262:Infusions, Intravenous; D013921:Thrombocytopenia / Q000209:etiology / Q000628:therapy*
D007136:Immunoglobulins; D006854:Hydrocortisone; D000212:Acyclovir