title: Laser angioplasty for limb salvage: observations on early results.
abstract: During a 27-month period laser thermal angioplasty (LTA) was attempted in 15 patients who had totally occluded segments of their superficial femoral--popliteal arteries (SFA) with limb-threatening ischemia (rest pain or tissue necrosis). In five patients (33%) laser perforation of the SFA precluded successful angioplasty, and those five patients have been excluded from further analysis. In the remaining 10 patients the prelaser angiogram demonstrated an average SVS/ISCVS runoff score of 7.7 (best possible score, 1; worst possible score, 10). Seven patients (70%) had occlusions of all infrapopliteal arteries. All 10 patients were available for clinical follow-up, and follow-up angiograms were available for eight patients (80%). Clinical failure was defined as recurrence of the clinical signs or symptoms for which the LTA was performed. After 6 months of follow-up clinical failures occurred in nine patients (90%). Four patients had no clinical improvement. Five patients had transient clinical improvement after LTA, and all subsequently had early recurrence of symptoms. The average time from LTA to recurrence of symptoms was 1.7 months. Seven patients had subsequent bypasses or amputations an average of 2.2 months after laser angioplasty. The SFA patency rate by life-table analysis was 25% at 6 months. The single patient with clinical success (at 12 months) had no tibial vessel disease evident on his prelaser angiogram, and he underwent a concomitant inflow procedure at the time of his LTA. We believe that the disappointing results in this small series of patients can be attributed to tibial vessel disease that was not addressed by this technique.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Surgery, Boston University School of Medicine, Mass.
authors.forename: J G
authors.initials: JG
authors.lastname: Wright
authors.forename: M
authors.initials: M
authors.lastname: Belkin
authors.forename: A J
authors.initials: AJ
authors.lastname: Greenfield
authors.forename: J K
authors.initials: JK
authors.lastname: Guben
authors.forename: T A
authors.initials: TA
authors.lastname: Sanborn
authors.forename: J O
authors.initials: JO
authors.lastname: Menzoian
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000800:Angioplasty, Balloon / Q000379:methods*; D001161:Arteriosclerosis / Q000628:therapy*; D005263:Femoral Artery; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy; D007866:Leg / Q000098:blood supply; D008875:Middle Aged; D011150:Popliteal Artery; D012008:Recurrence; D013997:Time Factors; D014654:Vascular Patency