[Value of nu/nu mice in the production of experimental amoebic keratitis with Acanthamoeba].
The intracorneal inoculation of nude mice with Acanthamoeba hatchetti amoebae induced a keratitis with disruption of corneal fibres, inflammatory response, secondary vascularization and amoebic trophozoites.
Paniagua-Crespo
E
E
Faculté de Médecine, Brest.
Hasle
D P
DP
Humphery-Smith
I
I
Bellon
C
C
Simitzis
A M
AM
D000048:Acanthamoeba / Q000302:isolation & purification; D015823:Acanthamoeba Keratitis / Q000469:parasitology / Q000473:pathology / Q000503:physiopathology; D000818:Animals; D003315:Cornea / Q000098:blood supply / Q000469:parasitology / Q000473:pathology; D004195:Disease Models, Animal; D005123:Eye / Q000473:pathology / Q000503:physiopathology; D005260:Female; D051379:Mice; D008819:Mice, Nude; D009504:Neutrophils / Q000473:pathology
Intérêt de la souris nu/nu dans la réalisation de la kératite expérimentale à amibes libres du genre Acanthamoeba.