Deoxy GTP accumulates in thymocytes, but not in T or B lymphocytes in simulated PNP deficiency.
Taddeo
A
A
Institute of Rheumatology, University of Siena, Italy.
Fairbanks
L D
LD
Simmonds
H A
HA
Duley
J A
JA
Morris
G S
GS
D001402:B-Lymphocytes / Q000187:drug effects / Q000378:metabolism*; D003849:Deoxyguanosine / Q000378:metabolism*; D006147:Guanine / Q000032:analysis / Q000494:pharmacology; D006801:Humans; D010430:Pentosyltransferases / Q000037:antagonists & inhibitors*; D011683:Purine-Nucleoside Phosphorylase / Q000037:antagonists & inhibitors* / Q000172:deficiency; D013601:T-Lymphocytes / Q000187:drug effects / Q000378:metabolism*; D013950:Thymus Gland / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*
D006147:Guanine; D010430:Pentosyltransferases; D011683:Purine-Nucleoside Phosphorylase; D003849:Deoxyguanosine