title: Vertical transmission of hepatitis B virus in Culex quinquefasciatus.
abstract: An investigation of the vertical transmission of hepatitis B virus (HBV) in Culex quinquefasciatus Say revealed the presence of low levels of the virus in adult F1 progeny from the first ovarian cycle of mosquitoes infected by feeding on HBV positive human blood. HBV was not transmitted vertically during the second, third and fourth ovarian cycles nor to the F2 generation. The salivary glands, ovaries and faeces of the F1 generation did not contain detectable levels of HBV. Progeny of female Cx quinquefasciatus mated with F1 males were negative for HBV.
authors.affiliation: Research Institute for Diseases in a Tropical Environment, South African Medical Research Council, Congella.
authors.forename: A
authors.initials: A
authors.lastname: Fouché
authors.forename: R M
authors.initials: RM
authors.lastname: Crewe
authors.forename: I M
authors.initials: IM
authors.lastname: Windsor
mesh_terms: D000818:Animals; D003465:Culex / Q000382:microbiology*; D005260:Female; D006509:Hepatitis B / Q000635:transmission*; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006513:Hepatitis B e Antigens / Q000097:blood; D006515:Hepatitis B virus / Q000302:isolation & purification*; D007303:Insect Vectors / Q000382:microbiology*; D008297:Male
chemical_list: D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens