Susceptibility testing of herpes viruses.
The plaque reduction or CPE assay has been the mainstay of virus sensitivity testing for both research and clinical work. These procedures have undergone a significant amount of methologic change in recent years. Almost completely lacking are results that clearly define the best parameters for correlating virus sensitivity to clinical outcome. Those few results that are available do not appear to show a direct correlation between virus sensitivity and clinical response.
Drew
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WL
Clinical Microbiology and Infectious Diseases, Mount Zion Hospital and Medical Center, San Francisco, California.
Matthews
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TR
D003470:Culture Media; D018139:Simplexvirus / Q000254:growth & development*; D010948:Viral Plaque Assay / Q000379:methods / Q000592:standards
D003470:Culture Media