[LHRH in the human hypothalamus. Immunohistochemical mapping in normal newborn infants or in sudden death infants].
The topographical distribution of neurons containing LHRH has been investigated in newborn hypothalamus using the peroxidase anti-peroxidase technique. In control subjects, LHRH immunoreactive (LHRH-IR) perikarya have been mainly observed essentially in the infundibular nucleus. The preoptic region displayed a moderate density of LHRH-IR cell bodies. High LHRH innervation was observed in the anterior hypothalamus in the lamina terminalis and in the mediobasal hypothalamus in the median eminence, and in the peri- and paraventricular regions. In sudden death infant syndrome, a comparable mapping was observed, except a low density in the mediobasal peri- and paraventricular areas.
Najimi
M
M
Laboratoire d'Anatomie pathologique, Faculté de Médecine Alexis-Carrel, Lyon.
Chigr
F
F
Jordan
D
D
Tommasi
M
M
Rebaud
P
P
Gallet
S
S
Kopp
N
N
D001931:Brain Mapping; D007987:Gonadotropin-Releasing Hormone / Q000032:analysis*; D006801:Humans; D007031:Hypothalamus / Q000032:analysis*; D007032:Hypothalamus, Anterior / Q000032:analysis; D007033:Hypothalamus, Middle / Q000032:analysis; D007034:Hypothalamus, Posterior / Q000032:analysis; D007150:Immunohistochemistry; D007223:Infant; D007231:Infant, Newborn; D012016:Reference Values; D013398:Sudden Infant Death
D007987:Gonadotropin-Releasing Hormone
LHRH dans l'hypothalamus humain. Etude cartographique immunohistochimique chez des nourrissons témoins ou décédés de "mort subite inexpliquée".