[Clinical electrophysiological studies of peroneal muscular atrophy--report of 32 cases].
Clinical, electromyography (EMG) and nerve conduction velocity (NCV) features of 32 cases with peroneal muscular atrophy (PMA) are reported. Twenty of the cases showed remarkably slow NCV: median SNCV (Fing 1-W) X = 21.0 m/s, (Fing 3-W) X = 22.7 m/s, motor latency (ML) X = 7.3 ms; tibial SNCV (hallux-ankle) X = 22.2 m/s and ML = X = 8.1 ms, which were consistent with Type 1 PMA. Twelve cases showed normal or moderately slow NCV: median SNCV (Fing 1-W) X = 41.9 m/s, (Fing 3-W) X = 47.0 m/s and ML X = 3.2 ms; tibial SNCV (halluxankle) X = 32.5 m/s and ML X = 4.8 ms which were consistent with Type 2 PMA. The difference between these two groups was very significant (P less than 0.01). Sural nerve biopsy performed in 6 cases showed that 5 corresponded with NCV classification. We conclude that careful NCV examination is necessary for classification of PMA.
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D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002607:Charcot-Marie-Tooth Disease / Q000503:physiopathology; D002648:Child; D004576:Electromyography; D004594:Electrophysiology; D005260:Female; D015417:Hereditary Sensory and Motor Neuropathy / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009133:Muscular Atrophy / Q000503:physiopathology*; D009431:Neural Conduction; D013497:Sural Nerve / Q000473:pathology