[Effect of ginsenosides Rb1 and Rg1 on lipid peroxidation of rat in vitro].
Ginsenosides Rb1 and Rg1 were found to inhibit to some degree both VitC-NADPH and Fe2(+)-cysteine induced lipid peroxidation of rat liver and brain microsomes. However, the inhibitory effect of Rb1 and Rg1 was obvious in liver microsomes, especially in Vit C-NADPH induced lipid peroxidation of liver microsomes. Besides, Rb1 was shown to be more potent than Rg1 in inhibiting VitC-NADPH or Fe2(+)-cysteine induced lipid peroxidation. The inhibitory effect of Rb1 on VitC-NADPH induced lipid peroxidation was similar to that of VitE at the same concentration.
Huang
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D000818:Animals; D001921:Brain / Q000378:metabolism; D036145:Ginsenosides; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D008861:Microsomes / Q000378:metabolism; D008862:Microsomes, Liver / Q000378:metabolism; D005894:Panax; D010946:Plants, Medicinal; D051381:Rats; D011919:Rats, Inbred Strains; D012503:Saponins / Q000494:pharmacology*; D014810:Vitamin E / Q000494:pharmacology
D036145:Ginsenosides; D012503:Saponins; D014810:Vitamin E; C035054:ginsenoside Rg1