Oxygen influences the subunit structure of cytochrome c oxidase in the slime mold Dictyostelium discoideum.
The conditions that promote the alternative expression of two nuclear-encoded subunits of cytochrome c oxidase in the slime mold Dictyostelium discoideum (Bisson, R., and Schiavo, G. (1986) J. Biol. Chem. 261, 4373-4376) have been investigated. Oxygen concentration seems to be the only factor able to cause the subunit switching. This result indicates that the polypeptide composition of the mitochondrial enzyme can be influenced by environmental conditions. The significance of this change is discussed.
Schiavo
G
G
Centro Consiglio Nazionale delle Ricerche Fisiologia dei Mitocondri, Università di Padova Italy.
Bisson
R
R
D004023:Dictyostelium / Q000201:enzymology* / Q000254:growth & development; D003576:Electron Transport Complex IV / Q000378:metabolism*; D005656:Fungal Proteins / Q000648:ultrastructure; D007425:Intracellular Membranes / Q000201:enzymology; D046911:Macromolecular Substances; D008565:Membrane Proteins / Q000648:ultrastructure; D008928:Mitochondria / Q000201:enzymology; D010100:Oxygen / Q000494:pharmacology*; D013997:Time Factors
D005656:Fungal Proteins; D046911:Macromolecular Substances; D008565:Membrane Proteins; D003576:Electron Transport Complex IV; D010100:Oxygen