[Dependence of the activity of enzymes of adenosine metabolism in hypothyroid rats on the level of somatotropin in the body].
Adenosine metabolism in hypothyrosis has been shown to decrease in thymocytes (5'-nucleotidase activity decreases by 18% and adenosine deaminase activity increases in thymocyte light fractions). Activation of adenosine synthesis and decay processes (5'-nucleotidase and adenosine deaminase activity increase by 65 and 72%, respectively) was found in the spleen of hypothyroid rats. Adenosine metabolism returns to normal in the spleen and thymocytes as a result of somatotropin action. Adenosine metabolism in the liver of hypothyroid rats remains unchanged.
Litvinenko
E A
EA
D015720:5'-Nucleotidase; D000241:Adenosine / Q000378:metabolism*; D000243:Adenosine Deaminase / Q000378:metabolism; D000818:Animals; D013006:Growth Hormone / Q000502:physiology*; D007037:Hypothyroidism / Q000201:enzymology* / Q000503:physiopathology; D008099:Liver / Q000201:enzymology; D008297:Male; D009708:Nucleotidases / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000201:enzymology; D013385:Succinate Dehydrogenase / Q000378:metabolism; D013950:Thymus Gland / Q000166:cytology / Q000201:enzymology
D013006:Growth Hormone; D013385:Succinate Dehydrogenase; D009708:Nucleotidases; D015720:5'-Nucleotidase; D000243:Adenosine Deaminase; D000241:Adenosine
Zavisimost' aktivnosti fermentov obmena adenozina u gipotireoidnykh krys ot urovnia somatotropina v organizme.