title: Study of a monoclonal antibody specific to epithelial cells of mammalian thymuses.
abstract: Hybridomas between spleen cells from BALB/c mice and Sp2/O-Ag14 mycloma cell line are performed by PEG fusion. An in vitro booster is realized with human thymic reticulo-epithelial cell cultures as antigen. A monoclonal antibody (3H9) directed against the thymic epithelium and stratified epithelia of mammals has been obtained and characterized.
authors.affiliation: Laboratoire d'Immunologie UFR Alexis Carrel, Lyon, France.
authors.forename: P
authors.initials: P
authors.lastname: Parvaz
authors.forename: C
authors.initials: C
authors.lastname: Auger
authors.forename: F
authors.initials: F
authors.lastname: Giraud
authors.forename: N
authors.initials: N
authors.lastname: Fabien
authors.forename: J R
authors.initials: JR
authors.lastname: Faure
authors.forename: J C
authors.initials: JC
authors.lastname: Monier
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D004848:Epithelium / Q000276:immunology; D005260:Female; D006801:Humans; D006825:Hybridomas / Q000276:immunology; D007075:Immunoglobulin M / Q000276:immunology; D007145:Immunoglobulin kappa-Chains / Q000276:immunology; D008322:Mammals / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C / Q000276:immunology; D009928:Organ Specificity; D013045:Species Specificity; D013950:Thymus Gland / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D007075:Immunoglobulin M; D007145:Immunoglobulin kappa-Chains