Neuroleptically induced dystonia in Huntington's disease: a case report.
A patient with Huntington's disease developed acute dystonia whilst treated with tiapride. Sulpiride and tetrabenazine also induced dystonia. The anticholinergic biperiden depressed the syndrome but worsened psychopathology. Finally a combination of tetrabenazine and clozapine was successful in treatment of both chorea and dystonia. According to this observation, acute dystonia may occur in Huntington's disease as a consequence of neuroleptic treatment.
Schott
K
K
Neurologische Universitätsklinik, Tübingen, FRG.
Ried
S
S
Stevens
I
I
Dichgans
J
J
D001549:Benzamides / Q000009:adverse effects*; D004421:Dystonia / Q000139:chemically induced*; D005260:Female; D006801:Humans; D006816:Huntington Disease / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D008875:Middle Aged; D013976:Tiapamil Hydrochloride / Q000009:adverse effects* / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
D001549:Benzamides; D013976:Tiapamil Hydrochloride