[Comparative features of the preventive action of carbamazepine and lithium carbonate in affective and schizoaffective psychoses].
The preventive properties of carbamazepine were studied and compared to those of lithium carbonate in patients suffering from affective and schizoaffective psychoses. Thirty-nine patients were examined. Of these, 19 patients received preventive treatment with carbamazepine and 20 with lithium carbonate. As to the preventive efficacy of carbamazepine, it turned out superior to lithium carbonate in all respects, particularly in cases of the monopolar depressive type of illness. The data obtained made it possible to analyze the possibilities of overcoming disadvantages of the preventive therapy with lithium carbonate by means of the use of carbamazepine or combined treatment with both the drugs, which considerably widens the potentialities of the preventive therapy of recurrent affective diseases. The method for the preventive therapy with carbamazepine and combined treatment including the use of lithium carbonate and carbamazepine are described.
Kostiukova
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EG
D000328:Adult; D000341:Affective Disorders, Psychotic / Q000517:prevention & control*; D001714:Bipolar Disorder / Q000517:prevention & control*; D002220:Carbamazepine / Q000008:administration & dosage / Q000627:therapeutic use*; D003863:Depression / Q000517:prevention & control*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008094:Lithium / Q000008:administration & dosage / Q000627:therapeutic use*; D016651:Lithium Carbonate; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000517:prevention & control*; D013997:Time Factors
D016651:Lithium Carbonate; D002220:Carbamazepine; D008094:Lithium
Sravnitel'nye osobennosti profilakticheskogo deĭstviia karbamazepina i uglekislogo litiia pri affektivnykh i shizoaffektivnykh psikhozakh.