Quantitative determination of residual sodium-cholate in tri(N-butyl)phosphate/sodium-cholate treated factor VIII-preparations.
A relatively simple and fast method for the quantitative determination of residual sodium-cholate in tri(n-butyl)phosphate/sodium-cholate treated factor VIII concentrate preparations was developed by solid-phase extraction and reversed-phase high-performance liquid chromatography.
Dengler
T
T
DRK Blutspendezentrale, Baden, FRG.
Kellner
S
S
Fürst
G
G
D019826:Cholic Acid; D002793:Cholic Acids / Q000032:analysis* / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D003902:Detergents / Q000032:analysis*; D005169:Factor VIII / Q000302:isolation & purification*; D006801:Humans; D010755:Organophosphates / Q000494:pharmacology*; D009943:Organophosphorus Compounds / Q000494:pharmacology*; D013056:Spectrophotometry, Ultraviolet; D013501:Surface-Active Agents / Q000032:analysis*
D002793:Cholic Acids; D003902:Detergents; D010755:Organophosphates; D009943:Organophosphorus Compounds; D013501:Surface-Active Agents; D005169:Factor VIII; C009524:tributyl phosphate; D019826:Cholic Acid