title: [Canthaxanthin retinopathy and macular pucker].
abstract: Canthaxanthine retinopathy is a crystalline retinopathy following oral ingestion of canthaxanthine-containing drugs. We describe the clinical course of a patient with canthaxanthine retinopathy and a preexisting idiopathic macular pucker. The ultrastructural findings of the macular pucker removed by vitreoretinal surgery are demonstrated. Granular material and lipid-like droplets, not usual for a macular pucker, are the major findings in this membrane. There is evidence that the granular material consists of canthaxanthine deposits, phagozytized by the cells of the epiretinal membrane.
authors.affiliation: Département d'ophtalmologie, Medical University, Lübeck, West Germany.
authors.forename: S
authors.initials: S
authors.lastname: Bopp
authors.forename: E L
authors.initials: EL
authors.lastname: el-Hifnawi
authors.forename: H
authors.initials: H
authors.lastname: Laqua
mesh_terms: D000368:Aged; D000975:Antioxidants / Q000627:therapeutic use; D016644:Canthaxanthin; D002338:Carotenoids / Q000009:adverse effects / Q000031:analogs & derivatives*; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D008266:Macula Lutea; D008566:Membranes / Q000648:ultrastructure; D008854:Microscopy, Electron; D012160:Retina / Q000648:ultrastructure*; D012164:Retinal Diseases / Q000139:chemically induced* / Q000150:complications / Q000473:pathology
chemical_list: D000975:Antioxidants; D002338:Carotenoids; D016644:Canthaxanthin
vernacular_title: Rétinopathie à la canthaxantine et syndrome de Jaffe.