title: The role of obesity, hypertension and diet in diabetes and its complications in the Spontaneous Hypertensive/NIH-corpulent rat.
abstract: The Spontaneous Hypertensive/NIH-corpulent rat is a recently developed genetic model of obesity and diabetes. The strain exhibits both metabolic and histopathological characteristics associated with non-insulin dependent diabetes mellitus in humans. This rodent model is unique in that glucose intolerance is expressed in both sexes and in both phenotypes.
authors.affiliation: Beltsville Human Nutrition Research Center, Agriculture Research Service, Maryland.
authors.forename: O E
authors.initials: OE
authors.lastname: Michaelis
authors.forename: N
authors.initials: N
authors.lastname: Carswell
authors.forename: M T
authors.initials: MT
authors.lastname: Velasquez
authors.forename: C T
authors.initials: CT
authors.lastname: Hansen
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000150:complications / Q000209:etiology* / Q000378:metabolism; D004032:Diet / Q000009:adverse effects; D005260:Female; D005838:Genotype; D006973:Hypertension / Q000150:complications*; D008297:Male; D009765:Obesity / Q000150:complications* / Q000235:genetics; D051381:Rats; D011918:Rats, Inbred SHR
chemical_list: D001786:Blood Glucose