title: Comparative study of the thromboresistance of Dacron combined with various polyurethanes.
abstract: In vitro tests were carried out on Dacron samples differently knitted and on Dacron vascular prostheses coated with various urethanes. All the materials were put in contact with human platelet-rich plasma; the subsequent assay of three platelet released substances, i.e. beta-thromboglobulin, platelet factor 4 and thromboxane B2, as well as the quantification of platelet retention, were used to establish the degree of thrombogenicity of the material itself. In some cases Dacron-urethanes composites showed better thromboresistance than any other materials conventionally used in vascular surgery.
authors.affiliation: Dental Research Institute, UCLA, Torrance.
authors.forename: D L
authors.initials: DL
authors.lastname: Leake
authors.forename: E
authors.initials: E
authors.lastname: Cenni
authors.forename: D
authors.initials: D
authors.lastname: Cavedagna
authors.forename: S
authors.initials: S
authors.lastname: Stea
authors.forename: G
authors.initials: G
authors.lastname: Ciapetti
authors.forename: A
authors.initials: A
authors.lastname: Pizzoferrato
mesh_terms: D001672:Biocompatible Materials; D001792:Blood Platelets / Q000378:metabolism; D001807:Blood Vessel Prosthesis; D008422:Materials Testing; D010973:Platelet Adhesiveness; D010976:Platelet Count; D010978:Platelet Factor 4 / Q000032:analysis; D011093:Polyethylene Terephthalates; D011140:Polyurethanes; D013927:Thrombosis / Q000517:prevention & control*; D013929:Thromboxane B2 / Q000032:analysis; D001620:beta-Thromboglobulin / Q000032:analysis
chemical_list: D001672:Biocompatible Materials; D011093:Polyethylene Terephthalates; D011140:Polyurethanes; D001620:beta-Thromboglobulin; D010978:Platelet Factor 4; D013929:Thromboxane B2