title: The comparative activity of lomefloxacin (SC-47111, NY-198) and other orally absorbable agents against Haemophilus influenzae and Branhamella catarrhalis.
abstract: We compared the in vitro activity of lomefloxacin with that of other agents against 336 strains of Haemophilus influenzae and Branhamella catarrhalis isolated from the respiratory tract of a predominantly adult and in-patient population. H. influenzae strains were usually not serotypable. No strains were resistant to lomefloxacin; all strains tested were susceptible to 0.25 micrograms/ml. The lomefloxacin MIC50 and MIC90 was 0.125 micrograms/ml.
authors.affiliation: Department of Clinical Microbiology, St. Boniface General Hospital, Winnipeg, Manitoba, Canada.
authors.forename: K R
authors.initials: KR
authors.lastname: Forward
authors.forename: P A
authors.initials: PA
authors.lastname: Degagne
authors.forename: K R
authors.initials: KR
authors.lastname: Bartlett
mesh_terms: D042462:4-Quinolones; D000284:Administration, Oral; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology*; D024841:Fluoroquinolones; D006193:Haemophilus influenzae / Q000187:drug effects*; D006801:Humans; D001936:Moraxella catarrhalis / Q000187:drug effects*; D015363:Quinolones
chemical_list: D042462:4-Quinolones; D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D015363:Quinolones; C053091:lomefloxacin