[Contact allergies caused by bufexamac].
Between 1983 and 1987, there were 24 cases of contact allergy due to bufexamac seen at the Dermatological Hospital of the University of Göttingen. Of these patients, 20 were female und four male. It was noticeable, that the course of disease was particularly protracted and refractory: 16 of 22 patients were hospitalized with an average duration of inpatient treatment of 2.9 weeks. Seven patients had a generalized allergic contact dermatitis. Five patients had used topical preparations containing bufexamac for only one week or less. In 15 of 24 patients, further epidermal sensitization could be found. In all forms of eczematous diseases, especially in patients with chronic eczema, contact allergy to bufexamac should be considered, even if bufexamac preparations were used for only a short time.
Geier
J
J
Fuchs
T
T
D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000368:Aged; D002019:Bufexamac / Q000008:administration & dosage / Q000009:adverse effects*; D002648:Child; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D006801:Humans; D006877:Hydroxamic Acids / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010328:Patch Tests
D006877:Hydroxamic Acids; D002019:Bufexamac
Kontaktallergien durch Bufexamac.