title: Effect of glycosaminoglycans on calcium oxalate crystal aggregation.
abstract: We have examined the effect of some glycosaminoglycan species on the aggregation of calcium oxalate monohydrate crystal by means of a Coulter counter. Our results showed that hyaluronic acid stimulated the aggregation at low concentrations but inhibited it at higher concentrations, and that both chondroitin sulfate and heparan sulfate acted as inhibitors. Glycosaminoglycans seem, therefore, to have quite different effects on the calcium oxalate crystal aggregation within their individual range of urinary concentration.
authors.forename: Y
authors.initials: Y
authors.lastname: Shirane
authors.forename: A
authors.initials: A
authors.lastname: Yamamoto
authors.forename: K
authors.initials: K
authors.lastname: Mizuta
authors.forename: S
authors.initials: S
authors.lastname: Kagawa
mesh_terms: D002129:Calcium Oxalate; D002809:Chondroitin Sulfates / Q000494:pharmacology; D003460:Crystallization; D006025:Glycosaminoglycans / Q000494:pharmacology*; D006497:Heparan Sulfate / Q000494:pharmacology; D006820:Hyaluronic Acid / Q000494:pharmacology
chemical_list: D002129:Calcium Oxalate; D002809:Chondroitin Sulfates; D006025:Glycosaminoglycans; D006497:Heparan Sulfate; D006820:Hyaluronic Acid