Translational efficiencies of polyomavirus late mRNA molecules that differ in the sequences of their 5' noncoding late leader exons.
Mouse NIH 3T6 cells were coinfected with two strains of polyomavirus that differ only in the sequences of their 5' noncoding late leader exons. Polysomes were isolated at late times after infection and probed with oligonucleotides specific for each strain. Results indicate that the sequence of the late leader does not play a role in the translational efficiency of late polyomavirus messages.
Rhee
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Department of Microbiology, University of Connecticut Health Center, Farmington 06032.
Carmichael
G G
GG
D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D005091:Exons; D008969:Molecular Sequence Data; D009154:Mutation; D009693:Nucleic Acid Hybridization; D011120:Polyomavirus / Q000235:genetics*; D011132:Polyribosomes / Q000032:analysis; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000032:analysis / Q000235:genetics*; D012367:RNA, Viral / Q000032:analysis / Q000235:genetics*
D012333:RNA, Messenger; D012367:RNA, Viral