title: The effect of cholinesterase inhibitors of SFEMG in myasthenia gravis.
abstract: We report four patients with myasthenia gravis (MG) in whom single-fiber electromyography (SFEMG) jitter measurements were normal in some muslces while they were taking pyridostigmine and became abnormal 2-14 days after the medication was discontinued. When the abnormality of neuromuscular transmission in MG is mild, cholinesterase inhibitors may mask the findings of increased jitter on SFEMG.
authors.affiliation: Duke University Medical Center, Durham, NC 27710.
authors.forename: J M
authors.initials: JM
authors.lastname: Massey
authors.forename: D B
authors.initials: DB
authors.lastname: Sanders
authors.forename: J F
authors.initials: JF
authors.lastname: Howard
mesh_terms: D000200:Action Potentials; D000293:Adolescent; D000328:Adult; D002800:Cholinesterase Inhibitors / Q000494:pharmacology*; D004576:Electromyography; D005260:Female; D006801:Humans; D009157:Myasthenia Gravis / Q000503:physiopathology*; D009435:Synaptic Transmission / Q000187:drug effects
chemical_list: D002800:Cholinesterase Inhibitors