title: Bilateral slowly progressive big blind spot syndrome.
abstract: A 33-year-old woman was found with bilateral enlargement of the blind spot without optic disc edema. Her bilateral peripapillary retinas appeared slightly decolored and elevated with obscure margins and fluorescein angiography indicating only slight hyperfluorescence in the late venous phase. Four years after her initial visit, both of her blind spots became enlarged further and dark adaptation was remarkably difficult. Peripapillary retinal lesions appearing as retinal pigmentary degeneration were evident with very definitive margins. The lesions showed strong hyperfluorescence in the arteriovenous phase owing to window defects. From these findings, it appears that bilateral big blind spots without optic disc edema may possibly result from peripapillary retinal degeneration, which may become evident at a much later date.
authors.affiliation: Department of Ophthalmology, School of Medicine, Kitasato University, Kanagawa, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Wakakura
authors.forename: K
authors.initials: K
authors.lastname: Furuno
mesh_terms: D000328:Adult; D003623:Dark Adaptation; D004585:Electrooculography; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D009898:Optic Disk; D012162:Retinal Degeneration / Q000150:complications*; D013577:Syndrome; D014792:Visual Acuity; D014794:Visual Fields