Morphometric studies on melanocytic tumors.
The authors have studied the longest and the shortest nuclear axes, the ratio between nuclear axes, the nuclear areas and the mitotic indices in melanocytic tumors and have noted progressive changes of the values in superficial spreading and in nodular melanoma as compared to nevi. The most powerful discriminants were the mitotic index and the ratio between the nuclear axes. These findings are discussed in relationship with the tumor progression.
Olinici
C D
CD
Giurgiuman
M
M
D002467:Cell Nucleus / Q000648:ultrastructure; D003937:Diagnosis, Differential; D006801:Humans; D007620:Karyometry; D008545:Melanoma / Q000175:diagnosis / Q000473:pathology*; D008938:Mitosis