[Mechanism of penetration of human type 3 parainfluenza virus into monkey kidney cells].
The mechanism of human parainfluenza type 3 virus penetration into monkey kidney cells was studied by morphological and biochemical methods. The results of electron microscopic studies permit a conclusion that the virus penetrates into the cells by the mechanism of receptor endocytosis. Analysis of subvirus structures in cytosole revealed two types of particles: nucleocapsids and structures of a larger size and lower buoyant density containing, in addition to NP protein, matrix (M) protein. It is presumed that nucleocapsid is released from the endocytic vacuole into the cytosole in association with M protein which is gradually eliminated from the nucleocapsid surface.
Anisimova
E
E
Sharova
N K
NK
Vonka
V
V
Bukrinskaia
A G
AG
D000818:Animals; D002460:Cell Line; D002522:Chlorocebus aethiops; D003593:Cytoplasm / Q000382:microbiology; D004705:Endocytosis; D007668:Kidney; D008854:Microscopy, Electron; D010224:Parainfluenza Virus 3, Human / Q000472:pathogenicity* / Q000502:physiology / Q000648:ultrastructure; D018108:Respirovirus / Q000472:pathogenicity*
Mekhanizm proniknoveniia paragrippoznogo virusa cheloveka tipa 3 v kletki pochek obez'iany.