[Study of the immunotropic properties of theophylline in lymphocyte culture].
The effect of theophylline on the activation of suppressor cells by histamine was studied in the experiments with mononuclear cells of blood of patients with bronchial asthma and healthy donors. Theophylline (1-5 micrograms/ml) was shown to be able of activating suppressed function of cells of the patients. Incubation of mononuclear cells of the healthy donors with theophylline did not change the process of suppressor formation in vitro.
Sokolov
E I
EI
Glan
P V
PV
Sashkina
T I
TI
D001249:Asthma / Q000276:immunology; D002478:Cells, Cultured; D006632:Histamine / Q000378:metabolism; D006801:Humans; D050378:T-Lymphocytes, Regulatory / Q000187:drug effects* / Q000276:immunology; D013806:Theophylline / Q000494:pharmacology*
D006632:Histamine; D013806:Theophylline
Izuchenie immunotropnykh svoĭstv teofillina v kul'ture limfotsitov.