Predictive testing for Huntington disease: I. Description of a pilot project in British Columbia.
The discovery of DNA markers linked to the gene causing Huntington disease (HD) has allowed the development of predictive testing programs for persons at-risk. A pilot program was established in British Columbia in November 1986. Ninety-five persons are currently enrolled. The major objective of this project is to introduce and evaluate a protocol for the delivery of test results to persons at-risk for HD. The criteria for entry and details of the psychosocial assessment before and after receiving a modified risk are presented. The guidelines that are developed from this project will have major applications for predictive testing programs for other late onset autosomal dominant disorders.
Fox
S
S
Department of Medical Genetics, University of British Columbia, Vancouver, Canada.
Bloch
M
M
Fahy
M
M
Hayden
M R
MR
D001955:British Columbia; D004247:DNA / Q000235:genetics; D005817:Genetic Counseling; D005819:Genetic Markers; D006801:Humans; D006816:Huntington Disease / Q000235:genetics* / Q000523:psychology; D010353:Patient Education as Topic / Q000379:methods; D010865:Pilot Projects; D012307:Risk Factors; D012803:Sick Role
D005819:Genetic Markers; D004247:DNA