title: Refined sublocalization of the human gene encoding the beta subunit of the S100 protein (S100B) and confirmation of a subtle t(9;21) translocation using in situ hybridization.
abstract: The gene which encodes the beta subunit of the S100 protein was mapped to 21q22.2----q22.3 by in situ hybridization. Concurrently, a subtle translocation involving this region of chromosome 21 and 9q34 was confirmed.
authors.affiliation: Department of Pathology, Queen's University, Kingston, Ontario, Canada.
authors.forename: A M
authors.initials: AM
authors.lastname: Duncan
authors.forename: J
authors.initials: J
authors.lastname: Higgins
authors.forename: R J
authors.initials: RJ
authors.lastname: Dunn
authors.forename: R
authors.initials: R
authors.lastname: Allore
authors.forename: A
authors.initials: A
authors.lastname: Marks
mesh_terms: D002874:Chromosome Mapping; D002891:Chromosomes, Human, Pair 21; D002899:Chromosomes, Human, Pair 9; D003001:Cloning, Molecular; D004247:DNA; D004314:Down Syndrome / Q000235:genetics; D006801:Humans; D007223:Infant; D007621:Karyotyping; D008297:Male; D009693:Nucleic Acid Hybridization; D009418:S100 Proteins / Q000235:genetics*; D014178:Translocation, Genetic
chemical_list: D009418:S100 Proteins; D004247:DNA