title: [Open clinical study on the efficacy and tolerance of acemetacin in rheumatoid arthritis and osteoarthrosis].
abstract: The authors report the results of an open clinical study of 60 outpatients of whom 20 were suffering from rheumatoid arthritis and 40 from osteoarthritis. The study was aimed at evaluating the efficacy and tolerability of the new indole derivative acemetacin and at a comparison with etodolac. The drug studied was found to be effective and to be tolerated better than indomethacin, particularly the absence of the most unpleasant side-effect of indole compounds, i.e., headache, was noted.
authors.forename: A
authors.initials: A
authors.lastname: Gospodinoff
authors.forename: L
authors.initials: L
authors.lastname: Fiore
authors.forename: B
authors.initials: B
authors.lastname: Dardano
authors.forename: D
authors.initials: D
authors.lastname: Fiore
authors.forename: P
authors.initials: P
authors.lastname: Scapato
mesh_terms: D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D017308:Etodolac; D005260:Female; D006801:Humans; D007210:Indoleacetic Acids / Q000627:therapeutic use*; D007213:Indomethacin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D007210:Indoleacetic Acids; D017308:Etodolac; C026784:acemetacin; D007213:Indomethacin
vernacular_title: Studio clinico aperto sull'efficacia e la tollerabilità dell'acemetacina nell'artrite reumatoide e nell'osteoartrosi.