The circadian rhythm of intact parathyroid hormone (1-84) and nephrogenous cyclic adenosine monophosphate in normal men.
A pronounced circadian rhythm has been demonstrated for intact parathyroid hormone (1-84) in the serum of normal male adults. The broad nocturnal rise of parathyroid hormone (1-84) secretion appears to be of physiological significance, for it is accompanied by a significant rise in nephrogenous cyclic adenosine monophosphate. The rate of return of parathyroid hormone (1-84) to baseline concentrations varies between individuals, an observation which has implications for the optimal time of sampling for the investigation of possible mild hyperparathyroidism.
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Endocrine Unit, Institute of Biochemistry, Royal Infirmary, Glasgow.
Fraser
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O'Reilly
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Beastall
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D000328:Adult; D002940:Circadian Rhythm; D000242:Cyclic AMP / Q000652:urine*; D006801:Humans; D008297:Male; D010281:Parathyroid Hormone / Q000097:blood*; D013223:Statistics as Topic
D010281:Parathyroid Hormone; D000242:Cyclic AMP