[Seborrhea-like dermatitis in the acquired immunodeficiency syndrome. Clinical, histological, and microbiological aspects and biochemical findings].
Seventy-six patients diagnosed as having seborrheic dermatitis (SD) were divided into two groups: group A (n = 22) otherwise healthy subjects (HIV negative) and group B (n = 54) HIV positive (ARC and AIDS cases). Thirty normal healthy subjects without SD were considered as control (group C). The three groups were subjected to the following analyses: A) skin surface lipids (SSL) and fatty acid pattern of cholesterol esters, wax esters, triglycerides and free fatty acids fractions in the affected areas; B) plasma levels of Vitamin E and fatty acids of phospholipids; C) erythrocyte glutathione peroxidase (3 cases for each group); D) frequency of Pityrosporum species in the affected areas; E) skin biopsy in the affected areas (2 cases for each group). Histological findings paralleled those reported in the Literature. SSL composition, fatty acid pattern and frequency of Pityrosporum species did not show significant variation among the 3 groups. On the contrary the blood levels of Vitamin E, polyunsaturated fatty acids of phospholipids and glutathione peroxidase were found significantly lower in A and B groups than in the controls.
Ippolito
F
F
Passi
S
S
Caprilli
F
F
Di Carlo
A
A
Morrone
A
A
Picardo
M
M
Valenzano
L
L
D000386:AIDS-Related Complex / Q000150:complications*; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000293:Adolescent; D000328:Adult; D012628:Dermatitis, Seborrheic / Q000097:blood / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D005260:Female; D005979:Glutathione Peroxidase / Q000097:blood; D006801:Humans; D008055:Lipids / Q000032:analysis; D008290:Malassezia / Q000302:isolation & purification; D008297:Male; D012867:Skin / Q000032:analysis; D014810:Vitamin E / Q000097:blood
D008055:Lipids; D014810:Vitamin E; D005979:Glutathione Peroxidase
La dermatite seborroica-like nella sindrome da immunodeficienza acquisita. Aspetti clinici, istologici, microbiologici e rilievi biochimici.