title: Protoporphyrinogen oxidase inhibition by three peroxidizing herbicides: oxadiazon, LS 82-556 and M&B 39279.
abstract: Three chemically unrelated peroxidizing molecules, namely oxadiazon [5-(t-butyl)-3-(2,4-dichloro-5-isopropoxyphenyl)-1,3,4-oxadiazol-2 -one], LS 82-556 [(S)3-N-(methylbenzyl)carbamoyl-5-propionyl-2,6-lutidine] and M&B 39279 [5-amino-4-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazol], are potent inhibitors of plant, yeast and mouse protoporphyrinogen oxidase.
authors.affiliation: Laboratoire des Herbicides, INRA, Dijon, France.
authors.forename: M
authors.initials: M
authors.lastname: Matringe
authors.forename: J M
authors.initials: JM
authors.lastname: Camadro
authors.forename: P
authors.initials: P
authors.lastname: Labbe
authors.forename: R
authors.initials: R
authors.lastname: Scalla
mesh_terms: D000818:Animals; D002736:Chloroplasts / Q000201:enzymology; D005420:Flavoproteins; D006540:Herbicides / Q000494:pharmacology; D051379:Mice; D008811:Mice, Inbred DBA; D008928:Mitochondria / Q000201:enzymology; D008930:Mitochondria, Liver / Q000201:enzymology; D024101:Mitochondrial Proteins; D009536:Niacinamide / Q000031:analogs & derivatives* / Q000494:pharmacology; D010069:Oxadiazoles / Q000494:pharmacology*; D010088:Oxidoreductases / Q000037:antagonists & inhibitors*; D044925:Oxidoreductases Acting on CH-CH Group Donors; D010944:Plants / Q000201:enzymology; D050768:Protoporphyrinogen Oxidase; D011720:Pyrazoles / Q000494:pharmacology*; D012441:Saccharomyces cerevisiae / Q000201:enzymology; D011198:Solanum tuberosum; D003313:Zea mays
chemical_list: D005420:Flavoproteins; D006540:Herbicides; D024101:Mitochondrial Proteins; D010069:Oxadiazoles; D011720:Pyrazoles; C058904:M&B 39279; D009536:Niacinamide; C058906:LS 82-556; C012466:oxadiazon; D010088:Oxidoreductases; D044925:Oxidoreductases Acting on CH-CH Group Donors; C493979:Ppox protein, mouse; D050768:Protoporphyrinogen Oxidase