The sign of Leser-Trélat: does it exist?
The sign of Leser-Trélat is usually regarded as a reliable cutaneous marker of internal malignancy. We have reviewed the literature and conclude that the evidence for a causal relation between eruptive seborrheic keratoses and cancer is meager.
Rampen
H J
HJ
Department of Dermatology, St Anna Hospital, Oss, The Netherlands.
Schwengle
L E
LE
D012628:Dermatitis, Seborrheic / Q000150:complications*; D006801:Humans; D007642:Keratosis / Q000150:complications*; D009369:Neoplasms / Q000150:complications*; D014860:Warts / Q000150:complications