The effect of humic acid on the toxicity and bioavailability of trivalent chromium.
The influence of humic acid (HA) on the toxicity and bioavailability of two forms of trivalent chromium (chromic chloride and chrome lignosulfonate) was evaluated using a common freshwater invertebrate, Daphnia pulex. With both compounds, the 50 mg/liter HA significantly decreased toxicity at all time points examined. The remaining two HA concentrations, 0.5 and 5 mg/liter, either had no influence or decreased the toxicity of the compounds. Humic acid appeared to have no influence on the bioavailability of chrome lignosulfonate. However, for chromic chloride, 5 and 50 mg/liter HA decreased the percentage free chromium at all time points examined.
Stackhouse
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Toxicology Program, College of Pharmacy and Health Sciences, Northeast Louisiana University, Monroe 71209-0470.
Benson
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D000818:Animals; D001682:Biological Availability; D002712:Chlorides; D002857:Chromium / Q000493:pharmacokinetics / Q000633:toxicity*; D017608:Chromium Compounds; D003621:Daphnia / Q000502:physiology; D006812:Humic Substances / Q000633:toxicity*; D007928:Lethal Dose 50; D013997:Time Factors
D002712:Chlorides; D017608:Chromium Compounds; D006812:Humic Substances; D002857:Chromium; C017133:chromous chloride