title: A nutritive control of independent ingestion in rat pups emerges by nine days of age.
abstract: The emergence of controls of independent ingestion in rat pups was studied using nutritive (0.6 M glucose in saline or water) and vehicle gastric preloads. Two hours after preloading, ingestive responses were assessed in a 30-minute test of feeding from the floor. In 6-day-olds, all preloads had similar effects on consumption of a milk diet. In 9-day-olds, however, glucose-water preloads inhibited intake compared to water preloads. This inhibition was secondary to an effect on gastric emptying. Glucose preloads also inhibited intake in 12- and 15-day-olds. Behavioral observations indicated that feeding patterns were altered in response to glucose preloads in 9-day-olds. These results provide evidence for the emergence of a nutritive, postgastric control of independent ingestion between 6 and 9 days of age.
authors.affiliation: Department of Psychology, Duke University, Durham, NC 27706.
authors.forename: S E
authors.initials: SE
authors.lastname: Swithers
authors.forename: W G
authors.initials: WG
authors.lastname: Hall
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D002149:Energy Intake / Q000502:physiology*; D004750:Enteral Nutrition; D005247:Feeding Behavior / Q000187:drug effects / Q000502:physiology*; D005260:Female; D005746:Gastric Emptying / Q000502:physiology; D005766:Gastrointestinal Contents / Q000032:analysis; D005947:Glucose / Q000008:administration & dosage* / Q000494:pharmacology; D008297:Male; D051381:Rats
chemical_list: D005947:Glucose