title: Ventilatory response kinetics and breathing pattern during exercise at different chemoreceptive drives.
abstract: For studying the effects of different chemoreceptive drives on the ventilatory responses to muscular work, experiments were carried out with 16 healthy men. They accomplished a 5-min exercise while breathing with different gas mixtures or after hyperventilation. As was shown, the rapid component of the exercise hyperpnea increased with intensifying the hypercapnic and/or hypoxic stimuli and was reduced or abolished with attenuation of these stimuli. At this, hypoxic drive exerted primary influence on the response kinetics. In the steady-state exercise effects of the chemoreceptive stimuli were modulated by biomechanical factors, which leads to a energetically optimum breathing pattern being formed.
authors.affiliation: Laboratory of respiratory physiology, I.P. Pavlov Institute of Physiology, USSR Academy of Sciences, Leningrad.
authors.forename: I S
authors.initials: IS
authors.lastname: Breslav
authors.forename: G G
authors.initials: GG
authors.lastname: Isaev
mesh_terms: D000280:Administration, Inhalation; D000328:Adult; D002245:Carbon Dioxide / Q000502:physiology; D002628:Chemoreceptor Cells / Q000502:physiology*; D015444:Exercise; D006801:Humans; D007700:Kinetics; D008297:Male; D010100:Oxygen / Q000502:physiology; D012132:Respiratory Muscles / Q000502:physiology
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen