title: Structural brain-imaging findings in affective disorders: an overview.
abstract: In recent years, numerous reports of structural brain abnormalities found with computerized tomography (CT) scans in affective disorders (e.g., major depression, bipolar disorder) have been published. More currently, magnetic resonance imaging (MRI) studies have provided additional data on brain structure in affective disorders. In this article, the various CT and MRI findings in affective disorders are reviewed, and the clinical and research relevance of those neuroanatomical findings are presented and discussed.
authors.affiliation: Department of Psychiatry, Ohio State University, College of Medicine, Columbus 43210-1228.
authors.forename: H A
authors.initials: HA
authors.lastname: Nasrallah
authors.forename: J A
authors.initials: JA
authors.lastname: Coffman
authors.forename: S C
authors.initials: SC
authors.lastname: Olson
mesh_terms: D001921:Brain / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D001927:Brain Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging; D002531:Cerebellum / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D002540:Cerebral Cortex / Q000000981:diagnostic imaging; D002552:Cerebral Ventricles / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D019964:Mood Disorders / Q000175:diagnosis* / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed