The comparative activity of lomefloxacin (SC-47111, NY-198) and other orally absorbable agents against Haemophilus influenzae and Branhamella catarrhalis.
We compared the in vitro activity of lomefloxacin with that of other agents against 336 strains of Haemophilus influenzae and Branhamella catarrhalis isolated from the respiratory tract of a predominantly adult and in-patient population. H. influenzae strains were usually not serotypable. No strains were resistant to lomefloxacin; all strains tested were susceptible to 0.25 micrograms/ml. The lomefloxacin MIC50 and MIC90 was 0.125 micrograms/ml.
Forward
K R
KR
Department of Clinical Microbiology, St. Boniface General Hospital, Winnipeg, Manitoba, Canada.
Degagne
P A
PA
Bartlett
K R
KR
D042462:4-Quinolones; D000284:Administration, Oral; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology*; D024841:Fluoroquinolones; D006193:Haemophilus influenzae / Q000187:drug effects*; D006801:Humans; D001936:Moraxella catarrhalis / Q000187:drug effects*; D015363:Quinolones
D042462:4-Quinolones; D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D015363:Quinolones; C053091:lomefloxacin