title: [Mortality of dilated myocardiopathies as a function of continuation of alcohol drinking. Multivariate analysis concerning 236 patients].
abstract: A retrospective study was conducted in 236 consecutive patients with dilated cardiomyopathy to determine the characteristics of the disease in heavy alcohol drinkers (n = 110) and to study its outcome, using a Cox model, according to whether the patients were abstainers (n = 49) or continued to indulge drinking (n = 61). At the time of diagnosis, pulmonary pressures were higher in heavy drinkers than in abstainers. During a mean follow-up period of 39 +/- 27 months, 80 patients died of heart disease, viz.: 46 out of 127 non-alcoholic patients (36.2 per cent), 31 out of 61 heavy drinkers (50.8 per cent) and 3 out of 49 patients who had given up alcohol (6.12 per cent). Thus, independently of other parameters, abstinence is a highly significant (P less than 0.001) factor of favourable prognosis in dilated cardiomyopathy.
authors.affiliation: Hôpital St-André, Bordeaux.
authors.forename: M
authors.initials: M
authors.lastname: Haissaguerre
authors.forename: B
authors.initials: B
authors.lastname: Fleury
authors.forename: A
authors.initials: A
authors.lastname: Gueguen
authors.forename: J
authors.initials: J
authors.lastname: Bonnet
authors.forename: P
authors.initials: P
authors.lastname: Lorente
authors.forename: J P
authors.initials: JP
authors.lastname: Nakache
authors.forename: J P
authors.initials: JP
authors.lastname: Broustet
authors.forename: M
authors.initials: M
authors.lastname: Dallochio
authors.forename: P
authors.initials: P
authors.lastname: Besse
mesh_terms: D000328:Adult; D000428:Alcohol Drinking; D000437:Alcoholism / Q000150:complications* / Q000503:physiopathology; D000704:Analysis of Variance; D002311:Cardiomyopathy, Dilated / Q000150:complications / Q000401:mortality* / Q000503:physiopathology; D005260:Female; D005500:Follow-Up Studies; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013997:Time Factors
vernacular_title: Mortalité des myocardiopathies dilatées en fonction de la poursuite de l'alcoolisation. Analyse multivariée sur 236 malades.