title: Sites of virus replication in the genital organs of boars inoculated in the cavum vaginale with pseudorabies virus.
abstract: To determine the sites of replication and the evolution of pseudorabies virus infection in boar genital organs, 5 Belgian Landrace boars were inoculated with pseudorabies virus unilaterally in the cavum vaginale of the testis. Virus replication took place only in cells of the tunica vaginalis of both cava vaginalia. Infection of the serosa led to exudative periorchitis and increased scrotal fluid, resulting in a severely swollen scrotal region. These experimental findings were similar to findings in boars with naturally acquired pseudorabies virus infection. Scrotal fluid contained large amounts of virus, making it a useful specimen for diagnosis of the disease in affected boars.
authors.affiliation: Laboratory of Virology, Faculty of Veterinary Medicine, University of Ghent, Belgium.
authors.forename: C
authors.initials: C
authors.lastname: Miry
authors.forename: M B
authors.initials: MB
authors.lastname: Pensaert
mesh_terms: D000818:Animals; D005455:Fluorescent Antibody Technique; D005837:Genitalia, Male / Q000382:microbiology* / Q000473:pathology; D011558:Herpesvirus 1, Suid / Q000302:isolation & purification / Q000502:physiology*; D008297:Male; D011557:Pseudorabies / Q000209:etiology / Q000382:microbiology*; D013552:Swine; D013553:Swine Diseases / Q000209:etiology / Q000382:microbiology*; D013737:Testis / Q000382:microbiology / Q000473:pathology; D014779:Virus Replication