title: [Testing of a hyperimmune serum in calves infected intranasally with Mycoplasma bovis].
abstract: Mycoplasma (M.) bovis hyperimmune serum was subcutaneously injected to 16 of 26 calves repeatedly intranasally infected with M. bovis, during and/or after experimental infection. Antibody titres between 1:32 and 1:256 were recorded by means of indirect haemagglutination from the calves treated. Transmission of film-inhibitory antibodies failed to work. Neither clinical manifestations nor pathologico-anatomic alterations to the lungs of experimentally infected animals were mitigated by hyperimmune serum treatment. M. bovis, in high germ counts, was re-isolated from nasal swabs, trachea, pulmonary lymph nodes, and inflammatory lung tissue of both treated and untreated calves.
authors.forename: A
authors.initials: A
authors.lastname: Brys
authors.forename: H
authors.initials: H
authors.lastname: Pfützner
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis*; D002417:Cattle; D002418:Cattle Diseases / Q000628:therapy*; D007116:Immunization, Passive; D008168:Lung / Q000473:pathology; D009174:Mycoplasma / Q000276:immunology*; D009175:Mycoplasma Infections / Q000628:therapy / Q000662:veterinary*; D013047:Specific Pathogen-Free Organisms
chemical_list: D000907:Antibodies, Bacterial
vernacular_title: Prüfung eines Hyperimmunserums bei intranasal mit Mycoplasma bovis infizierten Kälbern.