Role of nafarelin in the management of endometriosis.
A large, multicenter, double-blind clinical trial established that the gonadotropin releasing hormone analog nafarelin relieves clinical symptoms, decreases laparoscopic scores and improves fertility in women with endometriosis. Side effects were limited to those attributable to hypoestrogenism.
Henzl
M R
MR
Department of Reproductive Medicine, Syntex Research, Palo Alto, California 94304.
D004311:Double-Blind Method; D004715:Endometriosis / Q000188:drug therapy*; D004967:Estrogens / Q000172:deficiency; D005260:Female; D005298:Fertility / Q000187:drug effects; D007987:Gonadotropin-Releasing Hormone / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D015337:Multicenter Studies as Topic; D017274:Nafarelin; D016032:Randomized Controlled Trials as Topic
D004967:Estrogens; D017274:Nafarelin; D007987:Gonadotropin-Releasing Hormone