[Fulminant acne in Klinefelter syndrome treated with testosterone. A side effect of anti-tallness therapy].
Acne lesions usually do not occur in patients with Klinefelter's syndrome (47 XXXY). But a 19 year old patient with Klinefelter's syndrome, under therapy with testosteronenantat (500 mg every two weeks over a period of 18 months) for treatment of excessively tall stature developed acne fulminans. Following discontinuation of testosterone treatment and isotretinoin therapy over 16 weeks skin lesions healed almost completely although with severe scars. In conclusion, high doses testosterone-treatment in excessively tall boys needs the additional care of dermatologist when mostly after a 7 months period acne begins to develop under this treatment.
Hartmann
A A
AA
Klinik für Haut-, Bayerischen Julius-Maximilians-Univesität Würzburg.
Burg
G
G
D000152:Acne Vulgaris / Q000139:chemically induced* / Q000188:drug therapy; D000328:Adult; D001827:Body Height / Q000187:drug effects; D005877:Gigantism / Q000517:prevention & control*; D012739:Gonadal Steroid Hormones / Q000097:blood; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage; D007713:Klinefelter Syndrome / Q000188:drug therapy*; D008297:Male; D012741:Sexual Maturation / Q000187:drug effects; D013739:Testosterone / Q000008:administration & dosage / Q000009:adverse effects*
D012739:Gonadal Steroid Hormones; D013739:Testosterone; D015474:Isotretinoin
Acne fulminans bei Klinefelter-Syndrom unter Testosteron. Eine Nebenwirkung der Antihochwuchstherapie.