Synthesis of 15-cis-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-9-de oxy-6,9 alpha-nitriloprostaglandin F1 methyl ester (OP-2507), a novel anti-cerebral ischemic agent.
Iguchi
S
S
Minase Research Institute, Ono Pharmaceutical Co., Ltd., Osaka, Japan.
Miyata
Y
Y
Miyake
H
H
Arai
Y
Y
Okegawa
T
T
Kawasaki
A
A
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D002545:Brain Ischemia / Q000517:prevention & control*; D004734:Energy Metabolism / Q000187:drug effects; D011464:Epoprostenol / Q000138:chemical synthesis* / Q000494:pharmacology / Q000627:therapeutic use / Q000031:analogs & derivatives; D007202:Indicators and Reagents; D051379:Mice
D007202:Indicators and Reagents; C049453:OP 2507; D011464:Epoprostenol