Characterization of vancomycin resistance in Enterococcus faecium and Enterococcus faecalis.
Vancomycin resistance in Enterococcus faecium 180, a clinical isolate from England, was studied. Resistance to vancomycin was transferable by conjugation to other enterococci. Expression of resistance was inducible and coincided with the appearance of a new membrane protein.
Nicas
T I
TI
Lilly Research Laboratories, Eli Lilly & Co., Indianapolis, Indiana 46285-0438.
Wu
C Y
CY
Hobbs
J N
JN
Preston
D A
DA
Allen
N E
NE
D001425:Bacterial Outer Membrane Proteins / Q000096:biosynthesis / Q000302:isolation & purification; D002473:Cell Wall / Q000378:metabolism; D004352:Drug Resistance, Microbial; D004591:Electrophoresis, Polyacrylamide Gel; D013293:Enterococcus faecalis / Q000187:drug effects* / Q000235:genetics; D006020:Glycopeptides / Q000494:pharmacology; D013291:Streptococcus / Q000187:drug effects* / Q000235:genetics; D017334:Teicoplanin; D014640:Vancomycin / Q000378:metabolism / Q000494:pharmacology*
D001425:Bacterial Outer Membrane Proteins; D006020:Glycopeptides; D017334:Teicoplanin; D014640:Vancomycin