[Adverse reactions caused by drugs in pediatrics].
The present study describes the results obtained in a screening program aimed at detecting adverse reactions to medication in children aged 1-8 years admitted to the Pediatrics Service of the University of Granada Hospital (Spain). The program is based on monitoring the patients for a period of 12 months. Of a total of 597 patients, adverse reactions were recorded in 4.4%. Within this group the reactions were classified as confirmed in 33.3%, probable in 30% and possible in 36.6%. Based on organs and systems, the CNS was most frequently affected (40%), followed in decreasing order by the digestive (37%) and cardiovascular systems (10%), skin (10%) and endocrine system (3%). The drugs most frequently involved were bronchodilators (40%), antibiotics (30%) and antiepileptics (20%). Among risk factors, polytherapy, hospitalization time and type of drug administered were the most important.
Vázquez de la Villa
A
A
Servicio de Pediatría, Hospital Universitario, Granada.
Luna del Castillo
J D
JD
Galdó Muñoz
G
G
Puche Cañas
E
E
D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D000927:Anticonvulsants / Q000009:adverse effects*; D001993:Bronchodilator Agents / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000139:chemically induced*; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012307:Risk Factors; D014839:Vomiting / Q000139:chemically induced*
D000900:Anti-Bacterial Agents; D000927:Anticonvulsants; D001993:Bronchodilator Agents
Reacciones adversas causadas por medicamentos en pediatría.