title: Septo-optic dysplasia (SOD) or DeMorsier syndrome.
abstract: The historical evolution of the DeMorsier syndrome is reviewed. As the emphasis shifted from the eye findings to endocrinological defects and as the syndrome was further expanded through more frequent and easier radiological examination, the concept appears to have expanded, raising questions as to the nature of the disease and its clinical expression. To determine pathogenesis and better define the extent of the disease, further observations are needed, including postmortem studies on patients with septo-optic dysplasia and related disorders.
authors.affiliation: Division of Neuropathology, Case Western Reserve University, Cleveland, Ohio 44106.
authors.forename: U
authors.initials: U
authors.lastname: Roessmann
mesh_terms: D007018:Hypopituitarism / Q000150:complications*; D009900:Optic Nerve / Q000002:abnormalities*; D012688:Septum Pellucidum / Q000002:abnormalities*; D013577:Syndrome