[Rosacea. Clinical features and treatment].
The paper describes clinical features, concepts in the pathogenesis, and therapeutical aspects of rosacea. Particular attention is paid to recent experiences on topical therapy with metronidazole. A Norwegian double-blind, multi-centre clinical trial compares metronidazole 1% cream applied twice daily with placebo cream in the treatment of 97 patients with rosacea. After eight weeks of treatment there was a statistically significant difference between the two regimens in favour of metronidazole cream. No important side effects were registered. It is concluded that 1% metronidazole cream is an effective and well-tolerated alternative to tetracycline in patients with papulopustular rosacea.
Bjerke
J R
JR
D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use*; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D012393:Rosacea / Q000175:diagnosis / Q000188:drug therapy*
D008795:Metronidazole
Rosacea. Klinikk og behandling.