title: [Immune status of patients with malignant melanoma during combined therapy including local ultra-high frequency hyperthermia].
abstract: Immune status was evaluated in patients with clinical stage I malignant melanoma randomized to receive either preoperative irradiation (27 Gy) alone or in combination with local microwave hyperthermia (before or after it). Mononuclear, total T-lymphocyte, T-helper, T-suppressor, B-lymphocyte and blood-immune complex levels were assayed. The analysis of immunologic parameters dynamics pointed to beneficial changes occurring in immunoregulating T-lymphocytes in patients receiving hyperthermia as a component of combined treatment.
authors.forename: D Ia
authors.initials: DIa
authors.lastname: Risina
authors.forename: I G
authors.initials: IG
authors.lastname: Zhakov
authors.forename: S Z
authors.initials: SZ
authors.lastname: Fradkin
authors.forename: E A
authors.initials: EA
authors.lastname: Zhabrid
mesh_terms: D000328:Adult; D000368:Aged; D000936:Antigen-Antibody Complex / Q000032:analysis*; D001402:B-Lymphocytes / Q000276:immunology; D003131:Combined Modality Therapy; D006801:Humans; D006979:Hyperthermia, Induced; D008214:Lymphocytes / Q000276:immunology*; D008545:Melanoma / Q000276:immunology / Q000532:radiotherapy / Q000628:therapy*; D008875:Middle Aged; D011300:Preoperative Care; D000078702:Radiofrequency Therapy; D011879:Radiotherapy Dosage; D016032:Randomized Controlled Trials as Topic; D012878:Skin Neoplasms / Q000276:immunology / Q000532:radiotherapy / Q000628:therapy*; D013601:T-Lymphocytes / Q000276:immunology; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
chemical_list: D000936:Antigen-Antibody Complex
vernacular_title: Immunnyĭ status bol'nykh so zlokachestvennoĭ melanomoĭ pri kombinirovannoĭ terapii s ispol'zovaniem lokal'noĭ SVCh-gipertermii.