title: [Treatment of pulmonary thromboembolism with extrinsic plasminogen activator. A case report].
abstract: A 49 year-old woman with acute pulmonary thromboembolism and severe hemodynamic impairment was successfully treated with tissue-type plasminogen activator (r-TPA). She did not have previous pulmonary or cardiac diseases. Thirty days after immobilization of the right ankle, she had a sudden onset of dyspnea, epigastrial pain and syncope. As heparin therapy was unsuccessful, 90 mg of IV r-TPA was administered. There was rapid clinical and hemodynamic improvement of her condition. Pulmonary scanning one week later was normal and she was discharged without symptoms 12 days after the acute episode.
authors.forename: L A
authors.initials: LA
authors.lastname: Silva
authors.forename: E
authors.initials: E
authors.lastname: Ribeiro
authors.forename: S P
authors.initials: SP
authors.lastname: Torossian
authors.forename: J L
authors.initials: JL
authors.lastname: Oliveira
authors.forename: R A
authors.initials: RA
authors.lastname: Salvadori
authors.forename: A
authors.initials: A
authors.lastname: Petrizzo
authors.forename: E D
authors.initials: ED
authors.lastname: Papa
authors.forename: E
authors.initials: E
authors.lastname: Aboud
authors.forename: R
authors.initials: R
authors.lastname: Duprat Filho
mesh_terms: D004562:Electrocardiography; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011877:Radionuclide Imaging; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
chemical_list: D006493:Heparin; D010959:Tissue Plasminogen Activator
vernacular_title: Tratamento do tromboembolismo pulmonar com ativador extrínseco do plasminogênio. Relato de caso.