[Effects of anesthesia induction with propofol on plasma renin activity and atrial natriuretic factor secretion. A preliminary study].
The authors have noted a substantial increase in plasma renin activity, when the patients were induced with propofol (2.5 mg.kg-1). Although a direct or an indirect effect of propofol may be suggested, the design of this study is not helpful in pointing out the responsibility of the drug in the observed effects. Further studies including peripheral vascular resistance measurements should be undertaken.
Journois
D
D
Hôpital Laënnec, Département d'Anesthésie-Réanimation Necker-Enfants Malades, Laënnec.
Safran
D
D
Laborde
K
K
Chanu
D
D
Dru
M
M
Drévillon
C
C
D000328:Adult; D000368:Aged; D000771:Anesthesia, Intravenous; D000777:Anesthetics; D009320:Atrial Natriuretic Factor / Q000097:blood*; D006801:Humans; D008875:Middle Aged; D010636:Phenols; D015742:Propofol; D012083:Renin / Q000097:blood*
D000777:Anesthetics; D010636:Phenols; D009320:Atrial Natriuretic Factor; D012083:Renin; D015742:Propofol
Effets de l'induction anesthésique au propofol sur l'activité rénine plasmatique (ARP) et la sécrétion de facteur natriurétique auriculaire (ANF). Etude préliminaire.