[Factors influencing the effectiveness of preventive treatment of febrile convulsions].
The influence of risk factors predisposing to recurrences was assessed in 103 children with febrile convulsions who were given prophylactic treatment with phenobarbitone, primidone or sodium valproate at adequate doses and whose compliance with treatment was monitored. There was a greater risk of recurrence among girls. Increasing risk was observed with decreasing age at which children suffered the first febrile convulsion. Neither a family history of epilepsy, failure of previous treatment, history of perinatal incidents, focal or prolonged febrile convulsions, recognition of neurological disease nor the number of previous febrile convulsions led to any significantly greater risk in these children. There was an increased tendency for recurrence with increasing interval between the first febrile convulsion and the start of prophylactic treatment.
Herranz Fernández
J L
JL
Sección de Neuropediatría, Hospital Nacional Marqués de Valdecilla, Facultad de Medicina, Universidad de Cantabria, Santander.
Armijo Simón
J A
JA
Arteaga Manjón-Cabeza
R
R
D000927:Anticonvulsants / Q000008:administration & dosage*; D002648:Child; D004341:Drug Evaluation; D004827:Epilepsy / Q000188:drug therapy / Q000453:epidemiology* / Q000235:genetics; D005260:Female; D005334:Fever / Q000517:prevention & control*; D006801:Humans; D008297:Male; D010634:Phenobarbital / Q000008:administration & dosage; D011324:Primidone / Q000008:administration & dosage; D012008:Recurrence; D012640:Seizures / Q000453:epidemiology / Q000235:genetics / Q000517:prevention & control*; D013030:Spain / Q000453:epidemiology; D014635:Valproic Acid / Q000008:administration & dosage
D000927:Anticonvulsants; D011324:Primidone; D014635:Valproic Acid; D010634:Phenobarbital
Factores que influyen en la eficacia del tratamiento profiláctico de las convulsiones febriles.