Comparative susceptibility of Mycoplasma pneumoniae to erythromycin, ciprofloxacin, and lomefloxacin.
Lomefloxacin was found to be comparable to ciprofloxacin in its ability to inhibit the in vitro growth of Mycoplasma pneumoniae (MIC range 2-8 mcg/ml), but it was significantly less active than erythromycin. Although 30 different strains from widely differing geographic areas and isolation time periods were examined, no macrolide-resistant strains were observed.
Cassell
G H
GH
Department of Microbiology, University of Alabama, Birmingham 35294.
Waites
K B
KB
Pate
M S
MS
Canupp
K C
KC
Duffy
L B
LB
D000890:Anti-Infective Agents / Q000494:pharmacology*; D002939:Ciprofloxacin / Q000494:pharmacology*; D004917:Erythromycin / Q000494:pharmacology*; D024841:Fluoroquinolones; D006801:Humans; D009177:Mycoplasma pneumoniae / Q000187:drug effects*; D015363:Quinolones
D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D015363:Quinolones; D002939:Ciprofloxacin; D004917:Erythromycin; C053091:lomefloxacin