Mean cellular volume of urinary red blood cells in investigation of hematuria.
The mean cellular volume (MCV) of urinary red blood cells (RBCs) of pediatric patients with glomerular (group I; n = 52) and nonglomerular (group II; n = 21) hematuria was determined using an automated blood-cell analyzer. Group I patients had a significantly lower MCV than group II (61 +/- 8 vs. 88 +/- 15 microns 3, mean +/- SD; p less than 0.001). With a MCV of 75 microns 3 taken as the dividing line between glomerular and nonglomerular hematuria, correct assessment of the site of bleeding was made in 67 of the 73 (92%) patients studied. Determination of the MCV of urinary RBCs is a simple noninvasive test for localizing the site of hematuria in pediatric patients.
Tsukahara
H
H
Yoshimoto
M
M
Morikawa
K
K
Okada
T
T
Kuroda
M
M
Sudo
M
M
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004909:Erythrocyte Indices; D004913:Erythrocytes, Abnormal; D005260:Female; D006417:Hematuria / Q000097:blood* / Q000209:etiology; D006801:Humans; D007223:Infant; D007678:Kidney Glomerulus; D008297:Male; D014556:Urine / Q000166:cytology