[Plasma and erythrocyte electrolytes in endogenous depression --neurophysiologic implications].
The serum concentration of sodium, potassium, magnesium, and calcium as well as the level of sodium, potassium, and magnesium in RBC were measured in 45 patients with endogenous depression. The group consisted of 30 female and 15 male patients in the age from 17 to 56 years, during the depressive phase of illness and in remission. The control group formed 31 healthy subjects, 22 female and 9 male aged 27-56 years. The concentration of all mentioned cations in erythrocytes during depressive phase was lower in female patients than among healthy controls. In the group of male depressive patients lower level of magnesium in serum and RBC and higher serum level of calcium was stated. The concentrations of measured electrolytes in both male and female patients in remission did not differ from the values in healthy persons which suggests the dependence of distribution changes of studied cations on the phase of illness. The disturbances of cations distribution in depression found in the study may be connected with the weakness of ATPases which transport these cations through the cell membrane.
Rybakowski
J
J
Jankowiak
E
E
D000251:Adenosine Triphosphatases / Q000502:physiology; D000293:Adolescent; D000328:Adult; D003866:Depressive Disorder / Q000097:blood*; D004573:Electrolytes / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D004573:Electrolytes; D000251:Adenosine Triphosphatases
Elektrolity osocza i erytrocytów w depresji endogennej--implikacje neurofizjologiczne.