Polyarthritis associated with cutaneous T cell lymphoma.
This is the first reported synovial biopsy of a patient with concurrent onset of cutaneous T cell lymphoma and polyarthritis. The biopsy revealed a nonspecific chronic inflammatory process. Immunoperoxidase technique using monoclonal antibodies showed a mixture of helper T cells, suppressor T cells and B cells in the synovial infiltrate. Tumor infiltration was not seen. Our findings indicate that the arthritis associated with cutaneous T cell lymphoma is most likely a reactive phenomenon.
Seleznick
M J
MJ
Department of Internal Medicine and Orthopedic Surgery, University of South Florida College of Medicine, Tampa 33612-4799.
Aguilar
J L
JL
Rayhack
J
J
Fenske
N
N
Espinoza
L R
LR
D000368:Aged; D001168:Arthritis / Q000209:etiology*; D001706:Biopsy; D006225:Hand; D006801:Humans; D008223:Lymphoma / Q000150:complications* / Q000473:pathology; D008297:Male; D012878:Skin Neoplasms / Q000150:complications* / Q000473:pathology; D013583:Synovial Membrane / Q000473:pathology; D013601:T-Lymphocytes; D006377:T-Lymphocytes, Helper-Inducer / Q000473:pathology; D050378:T-Lymphocytes, Regulatory / Q000473:pathology; D014955:Wrist Joint