title: [Experience with clarithromycin in pediatric patients].
abstract: Clarithromycin (TE-031, A-56268), a newly synthesized macrolide antibiotic, was administered to children and its efficacy was examined. The clinical efficacy rate of TE-031 was 88.5% in 26 patients with pediatric infections. This rate was regarded as quite high. A side effect, transaminase elevation, was observed in 1 out of the 26 patients but it was subsided after a cessation of the antibiotic treatment. TE-031 was considered to be effective antibiotic for the infectious disease in the pediatric fields because of highly efficacy rate.
authors.affiliation: Department of Pediatrics, School of Medicine, Mie University.
authors.forename: K
authors.initials: K
authors.lastname: Iguchi
authors.forename: H
authors.initials: H
authors.lastname: Kawaguchi
authors.forename: H
authors.initials: H
authors.lastname: Kamiya
authors.forename: M
authors.initials: M
authors.lastname: Sakurai
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D017291:Clarithromycin; D004341:Drug Evaluation; D004760:Enterocolitis / Q000188:drug therapy* / Q000378:metabolism / Q000382:microbiology; D004917:Erythromycin / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000493:pharmacokinetics / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000378:metabolism / Q000382:microbiology
chemical_list: D004917:Erythromycin; D017291:Clarithromycin