title: Osteomyelitis-like bone lesions in acne fulminans.
abstract: Two young males with acne fulminans (AF) are described. In addition to severe skin lesions, they had musculoskeletal symptoms including bacteriologically negative osteolytic lesions in the clavicles. Both patients received antibiotics for suspected septic infections. The response was unsatisfactory in both patients, and combination treatment with prednisolone was started. A favourable response was observed, and a relapse occurring in the first patient was controlled by steroids alone. The possible pathomechanism of bone lesions in AF is discussed.
authors.affiliation: Department of Dermatology, University Central Hospital, Tampere, Finland.
authors.forename: S L
authors.initials: SL
authors.lastname: Pauli
authors.forename: T
authors.initials: T
authors.lastname: Valkeakari
authors.forename: L
authors.initials: L
authors.lastname: Räsänen
authors.forename: M L
authors.initials: ML
authors.lastname: Tuomi
authors.forename: T
authors.initials: T
authors.lastname: Reunala
mesh_terms: D000152:Acne Vulgaris / Q000150:complications*; D000293:Adolescent; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D010019:Osteomyelitis / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D011877:Radionuclide Imaging; D012008:Recurrence; D013752:Tetracycline / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D011239:Prednisolone; D013752:Tetracycline