Determination of the effects of inhibition of pulmonary thromboxane A2 synthase activity, in vivo and in vitro.
McNamara
D B
DB
Department of Pharmacology, Surgery and Anesthesiology, Tulane University School of Medicine, New Orleans, Louisiana 70112.
Kerstein
M D
MD
Harrington
J K
JK
Bellan
J A
JA
Graybar
G B
GB
Hyman
A L
AL
Kadowitz
P J
PJ
D000818:Animals; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000378:metabolism; D002415:Cats; D005260:Female; D007093:Imidazoles / Q000494:pharmacology*; D008168:Lung / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D008297:Male; D008861:Microsomes / Q000187:drug effects / Q000378:metabolism; D011453:Prostaglandins / Q000096:biosynthesis; D011725:Pyridines / Q000494:pharmacology*; D012016:Reference Values; D012129:Respiratory Function Tests; D013930:Thromboxane-A Synthase / Q000037:antagonists & inhibitors*
D001095:Arachidonic Acids; D007093:Imidazoles; D011453:Prostaglandins; D011725:Pyridines; D016718:Arachidonic Acid; C037787:pirmagrel; D013930:Thromboxane-A Synthase