The effects of atriopeptin and angiotensin on the rat right ventricle.
1. Atriopeptin had no effect, whereas angiotensin increased the force of the electrically stimulated ventricle muscle. 2. Atriopeptin and angiotensin had no effect on the combined response to muscle stimulation and isoprenaline. 3. Following incubation of the ventricle with [3H]noradrenaline, atriopeptin and angiotensin had no effect on the spontaneous or nerve-evoked outflow of radioactivity.
Doggrell
S A
SA
Department of Pharmacology, School of Medicine, University of Auckland, New Zealand.
D000804:Angiotensin II / Q000494:pharmacology*; D000818:Animals; D009320:Atrial Natriuretic Factor / Q000494:pharmacology*; D004558:Electric Stimulation; D006321:Heart / Q000187:drug effects* / Q000502:physiology; D066298:In Vitro Techniques; D007545:Isoproterenol / Q000494:pharmacology; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D000804:Angiotensin II; D009320:Atrial Natriuretic Factor; D007545:Isoproterenol