title: [Immune response to influenza vaccination].
abstract: The present study investigated the level of immunity of the population against three strains of the influenza virus (A Chile/1/83 -A Philippines/2/82 and B URSS/100/83) before and three months after vaccination, and the immune response to whole virus vaccine as compared with fragmented virus vaccine. A high percentage of the population had titers greater than or equal to 1/10 before vaccination for the Chile (54%) and Philippines (65.7%) strains, while titers against the URSS strain were lower (25.4%). There was a definitive increase in antibody titer in the vaccinated population, although it was lower than expected. The overall response to both vaccines, with protecting titers greater than or equal to 1/40 after vaccination was 65.2% for the Chile strain, 74.6% for the Philippines strain, and 15% for the URSS strain. No differences in the overall immune response were found between the groups vaccinated with whole and fragmented virus.
authors.forename: I
authors.initials: I
authors.lastname: Alvarez
authors.forename: J
authors.initials: J
authors.lastname: Corral
authors.forename: A
authors.initials: A
authors.lastname: Arranz
authors.forename: A
authors.initials: A
authors.lastname: Foruria
authors.forename: V
authors.initials: V
authors.lastname: Landa
authors.forename: J R
authors.initials: JR
authors.lastname: Lejarza
authors.forename: L
authors.initials: L
authors.lastname: Marijuán
authors.forename: J M
authors.initials: JM
authors.lastname: Martínez
mesh_terms: D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis*; D005260:Female; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D009980:Influenza A virus / Q000276:immunology*; D009981:Influenza B virus / Q000276:immunology*; D007252:Influenza Vaccines / Q000276:immunology*; D008297:Male; D008875:Middle Aged
chemical_list: D000914:Antibodies, Viral; D007252:Influenza Vaccines
vernacular_title: Estudio sobre la respuesta inmunitaria a la vacunación antigripal.