[Experimental study of qi deficiency syndrome and Codonopsis pillosulae and Astragalus injection on the immune response in mice].
According to TCM theory "hunger impairs one's Qi", the authors had made mouse model of Qi deficiency syndrome (QDS) through controlling amount of food fed. Compared with mice of normal group, the body weight, thymus index and spleen index obviously decreased in mice of QDS group. The similar effects on humoral immunity and cell-mediated immunity were also obtained. It was found that the Codonopsis pilosulae and Astragalus Injection (CPAI) possessed the promoting action of thymus index, spleen index, humoral immunity and cell mediated immunity on QDS mice and normal mice except spleen index. However, QDS mice were more sensitive to CPAI than the normal mice. 4 x 10(9) SRBC/mouse was administered to normal donor mice by i.p., the super-optimal immunization could obviously induce generation of Ts cells. The CPAI could also reduce generation of Ts cells. This paper had proved that the inherent relation between Qi and immune response of organism, and that the CPAI could promote immune response by means of reducing Ts cells.
Zhou
Y
Y
Yan
X Z
XZ
D000276:Adjuvants, Immunologic; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D007111:Immunity, Cellular / Q000187:drug effects; D008297:Male; D008516:Medicine, Chinese Traditional; D051379:Mice; D008807:Mice, Inbred BALB C; D050378:T-Lymphocytes, Regulatory / Q000187:drug effects*
D000276:Adjuvants, Immunologic; D004365:Drugs, Chinese Herbal