title: Xiaoke tea, a Chinese herbal treatment for diabetes mellitus.
abstract: Xiaoke tea, a traditional Chinese treatment for diabetes mellitus, lowered blood glucose concentrations in streptozotocin diabetic mice. To investigate Xiaoke clinically, a double-blind crossover study was undertaken in 12 non-insulin-treated diabetic patients. Xiaoke tea and ordinary tea (infusion of 2.72 g, 4 times daily) were consumed in random order for 4 weeks. A standard breakfast meal was taken before and after each treatment period. Xiaoke did not significantly affect glycosylated haemoglobin, basal or post-breakfast serum glucose and insulin concentrations, intermediary metabolite concentrations, triglyceride and cholesterol. No adverse side-effects of Xiaoke were evident.
authors.affiliation: Diabetic Clinic, General Hospital, Birmingham, UK.
authors.forename: P J
authors.initials: PJ
authors.lastname: Hale
authors.forename: P M
authors.initials: PM
authors.lastname: Horrocks
authors.forename: A D
authors.initials: AD
authors.lastname: Wright
authors.forename: M G
authors.initials: MG
authors.lastname: Fitzgerald
authors.forename: M
authors.initials: M
authors.lastname: Nattrass
authors.forename: C J
authors.initials: CJ
authors.lastname: Bailey
mesh_terms: D001786:Blood Glucose / Q000378:metabolism*; D002986:Clinical Trials as Topic; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000188:drug therapy*; D004311:Double-Blind Method; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007328:Insulin / Q000097:blood*; D008297:Male; D008875:Middle Aged; D013662:Tea
chemical_list: D001786:Blood Glucose; D004365:Drugs, Chinese Herbal; D006442:Glycated Hemoglobin; D007328:Insulin; D013662:Tea