Brain death in moderately injured rat brains by in vivo P-31 NMR spectroscopy.
In the course of a systematic in vivo P-31 NMR study of moderately insulted rat brains, some brains died after such injury. Changes in high-energy phosphate metabolism of these brains after injury were rationalised by the aid of a model based on the depletion of an insoluble Pi pool followed by depletion of PCr and ATP pools.
Ishige
N
N
Dipartimento di Chimica, Università della Calabria, Arcavacata di Rende (CS), Italy.
Laschi
F
F
Pogliani
L
L
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000378:metabolism; D001926:Brain Death; D001930:Brain Injuries / Q000378:metabolism / Q000503:physiopathology*; D004734:Energy Metabolism; D006863:Hydrogen-Ion Concentration; D000860:Hypoxia; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D010710:Phosphates / Q000378:metabolism; D010725:Phosphocreatine / Q000378:metabolism; D010758:Phosphorus; D051381:Rats
D010710:Phosphates; D010725:Phosphocreatine; D010758:Phosphorus; D000255:Adenosine Triphosphate