[The effect of vitamins A, E, C, P and PP on blood coagulation in experimental thromboplastinemia].
In experiments on white rats it was established that combination of vitamins A, E, P and C, without producing a significant change in normal hemocoagulation, induces weakening of hypocoagulemia developing during coagulation activation induced by surgery or exogenic thromboplastinemia in experiment. In exogenic thromboplastinemia the development of hypocoagulemia is effectively prevented by combination of vitamins A, E, C and P, when they are administered in doses similar to therapeutic, during 12 days, before interference provoking activation of blood coagulation. A conclusion has been made on the expediency of the study of possibility of using the above combination of vitamins for nonspecific prophylaxis of thrombohemorrhagic complications in surgery.
Bysheskiĭ
A Sh
ASh
Galian
S L
SL
Shafer
V M
VM
Solov'ev
V G
VG
D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology / Q000627:therapeutic use; D001777:Blood Coagulation / Q000187:drug effects*; D001791:Blood Platelet Disorders / Q000517:prevention & control*; D002135:Calcium-Binding Proteins; D005299:Fertility Agents / Q000494:pharmacology / Q000627:therapeutic use; D009536:Niacinamide / Q000494:pharmacology / Q000627:therapeutic use; D027361:Organic Anion Transporters; D051381:Rats; D013925:Thromboplastin / Q000032:analysis*; D014801:Vitamin A / Q000494:pharmacology / Q000627:therapeutic use; D014810:Vitamin E / Q000494:pharmacology / Q000627:therapeutic use; D014815:Vitamins / Q000494:pharmacology / Q000627:therapeutic use*
D002135:Calcium-Binding Proteins; D005299:Fertility Agents; D027361:Organic Anion Transporters; D014815:Vitamins; D014801:Vitamin A; C008822:citrin; D014810:Vitamin E; D009536:Niacinamide; D013925:Thromboplastin; D001205:Ascorbic Acid
Vliianie vitaminov A, E, C, P i PP na svertyvanie krovi pri éksperimental'noĭ tromboplastinemii.