[Uropathogenic Serratia marcescens of hospital origin: analysis of the adhesion mechanism of 2 strains].
We isolated 2 Serratia marcescens strains, fim (0) and fim (-), from patients with urinary tract infection. Adhesion properties were studied by hemagglutination, response of uroepithelial cells and electron microscopy techniques. S marcescens fim (+) showed high adherence to uroepithelial cells, hemagglutination capacity and peculiar electron microscopy characteristics. All of these are absent in the fim (-) variety. The fim (+) strain was resistant to nitrofurantoin, nalidixic acid, tetracyclin, ampicillin, gentamycin, cefradine, cephotaxime and cotrimoxazole, whereas the fim (-) strain was sensitive to all. An absence of extrachromosomal DNA was demonstrated in S marcescens fim (+) suggesting that its characteristics are not coded in plasmids.
Padilla
C
C
Brevis
P
P
Padilla
R
R
D001422:Bacterial Adhesion; D003428:Cross Infection / Q000382:microbiology; D004352:Drug Resistance, Microbial; D008826:Microbial Sensitivity Tests; D012706:Serratia marcescens / Q000187:drug effects / Q000472:pathogenicity*; D014552:Urinary Tract Infections / Q000382:microbiology; D014774:Virulence
Serratia marcescens uropatogenicas de origen hospitalario. analisis del mecanismo adherente de dos cepas.