Genetic analysis of the N transcription antitermination system of phage lambda.
Regulation of coliphage lambda gene expression occurs, in part, by a process of termination and antitermination of transcription. The N gene product, one of two lambda encoded antitermination proteins, acts with host encoded proteins, Nus, at sites, nut, located downstream of the early promoters to render the transcribing RNA polymerase resistant to many downstream termination signals. We discuss the nature of some of the proteins and sites involved in this process.
Friedman
D I
DI
Microbiology and Immunology, University of Michigan Medical School, Ann Arbor 48109-0620.
Granston
A E
AE
Thompson
D
D
Schauer
A T
AT
Olson
E R
ER
D000595:Amino Acid Sequence; D010582:Bacteriophage lambda / Q000235:genetics*; D001483:Base Sequence; D015967:Gene Expression Regulation, Viral; D005814:Genes, Viral; D008969:Molecular Sequence Data; D012689:Sequence Homology, Nucleic Acid; D014158:Transcription, Genetic; D054334:Viral Regulatory and Accessory Proteins / Q000235:genetics / Q000502:physiology*
C059417:N protein, Bacteriophage lambda; D054334:Viral Regulatory and Accessory Proteins