Neuropsychological and biomedical assessment of depression-dementia syndromes.
Evaluating the clinical significance of cognitive dysfunction in patients who exhibit signs of both depression and dementia is one of the more formidable challenges in psychiatry. This article reviews cognitive dysfunction associated with depression, the concept of "pseudodementia," and the syndromal phenomenology of coexisting depression and Alzheimer's-type dementia. The state of the art in neuropsychologic, electroencephalographic, metabolic, and neuroradiographic techniques for evaluating dementia and depression syndromes will be discussed, as will implications for the treatment of such patients.
Stoudemire
A
A
Department of Psychiatry, Emory University Hospital, Atlanta, Georgia.
Hill
C
C
Gulley
L R
LR
Morris
R
R
D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000523:psychology; D015415:Biomarkers / Q000097:blood; D003072:Cognition Disorders / Q000175:diagnosis / Q000523:psychology; D003866:Depressive Disorder / Q000175:diagnosis* / Q000523:psychology; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D005162:Factitious Disorders / Q000175:diagnosis* / Q000523:psychology; D006801:Humans; D009483:Neuropsychological Tests
D015415:Biomarkers