Differential clastogenic sensitivity of heterochromatin and euchromatin: evidence from an in vivo study made on a submammalian vertebrate.
One of the properties often attributed to heterochromatin is its susceptibility to induced aberrations and exchanges. However, earlier studies made mostly on different mammalian in vitro cell lines on the distribution of aberrations within euchromatin and heterochromatin at metaphase chromosome level have given contradictory results. In the present study, an attempt has been made to evaluate the clastogenic sensitivity of heterochromatin and euchromatin using somatic chromosome complements of a submammalian vertebrate as experimental model and considering both chromosome aberrations and SCEs as end points.
Banerjee
S N
SN
Department of Zoology, Burdwan University, India.
Chakrabarti
S
S
D000818:Animals; D001854:Bone Marrow Cells; D002025:Bufonidae; D002843:Chromatin / Q000502:physiology* / Q000528:radiation effects / Q000648:ultrastructure; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002874:Chromosome Mapping; D005260:Female; D006570:Heterochromatin / Q000502:physiology* / Q000528:radiation effects / Q000648:ultrastructure; D007621:Karyotyping; D008297:Male; D008677:Metaphase; D016296:Mutagenesis; D014916:Whole-Body Irradiation
D002843:Chromatin; D006570:Heterochromatin