Cerebral amyloidosis, ageing and Alzheimer's disease; a contribution from studies on Down's syndrome.
Observations concerning the time course of deposition of amyloid within the brain substance and blood vessels in persons, of different ages, with Down's syndrome are used to provide a perspective on the nature of the process of cerebral amyloidosis in Alzheimer's disease.
Mann
D M
DM
Department of Pathology, University of Manchester, Great Britain.
D000293:Adolescent; D000328:Adult; D000375:Aging / Q000378:metabolism* / Q000473:pathology; D000544:Alzheimer Disease / Q000378:metabolism* / Q000473:pathology; D000682:Amyloid / Q000378:metabolism; D016229:Amyloid beta-Peptides; D000686:Amyloidosis / Q000378:metabolism* / Q000473:pathology; D002648:Child; D004314:Down Syndrome / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D008875:Middle Aged
D000682:Amyloid; D016229:Amyloid beta-Peptides