[Experimental study of composites of bovine bone morphogenetic protein and bio-active glass ceramic implanted into surgically produced periodontal bony defects in dogs].
Bovine bone morphogenetic protein (bBMP) was incorporated with bio-active glass ceramic (BGC). The composite of bBMP-BGC and BGC were implanted into the surgically produced periodontal osseous defects in dogs. Observations at 10, 16, 20, and 24 weeks show that the implants of BMP-BGC have the ability of bone induction and enhance the regeneration of periodontal bony defects in a relatively short time, but the implants of BGC alone only have the ability of bone-conduction, these is no bone-induction ability, and made a more long time in repairing the periodontal bony defects.
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D000818:Animals; D001672:Biocompatible Materials; D019485:Bone Morphogenetic Proteins; D015921:Dental Implants; D003776:Dental Porcelain; D004285:Dogs; D006133:Growth Substances / Q000627:therapeutic use; D008297:Male; D051379:Mice; D010510:Periodontal Diseases / Q000628:therapy*; D011506:Proteins / Q000627:therapeutic use*
D001672:Biocompatible Materials; D019485:Bone Morphogenetic Proteins; D015921:Dental Implants; D006133:Growth Substances; D011506:Proteins; D003776:Dental Porcelain