title: [Molecular biological mechanisms of photodynamic therapy].
abstract: The biological mechanisms of photodynamic therapy, a new approach to the treatment of malignant lesions, are considered. The data on chemical composition of hematoporphyrin derivative are given, the photophysical and photochemical reactions caused by photosensitizer distribution in organism and cell, as well mechanisms of photodestruction of cells and cell organelles.
authors.forename: V A
authors.initials: VA
authors.lastname: Kirvialene
authors.forename: Zh B
authors.initials: ZhB
authors.lastname: Lukshene
authors.forename: B A
authors.initials: BA
authors.lastname: Iuodka
mesh_terms: D000818:Animals; D017324:Hematoporphyrin Derivative; D006415:Hematoporphyrins / Q000493:pharmacokinetics / Q000627:therapeutic use; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000378:metabolism; D009374:Neoplasms, Experimental / Q000188:drug therapy / Q000378:metabolism; D010777:Photochemistry; D010778:Photochemotherapy; D055585:Physical Phenomena; D010825:Physics; D011838:Radiation-Sensitizing Agents / Q000493:pharmacokinetics / Q000627:therapeutic use
chemical_list: D006415:Hematoporphyrins; D011838:Radiation-Sensitizing Agents; D017324:Hematoporphyrin Derivative
vernacular_title: Molekuliarno-biologicheskie mekhanizmy fotodinamicheskoĭ terapii.