Chromosome studies of males in an institution for the mentally handicapped.
Karyotypes were examined in 512 (91.9%) of 557 male patients in an institution for the mentally handicapped. A total of 110 (21.5%) had an abnormal karyotype: 65 (12.7%) with Down's syndrome, 30 (5.9%) with the fragile X syndrome, 13 (2.5%) with autosomal anomalies other than Down's syndrome (12 unbalanced, one balanced), and two (0.4%) with sex chromosome anomalies.
English
C J
CJ
Department of Human Genetics, University of Newcastle upon Tyne.
Davison
E V
EV
Bhate
M S
MS
Barrett
L
L
D000782:Aneuploidy; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D004314:Down Syndrome / Q000235:genetics; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics*; D007621:Karyotyping; D008297:Male; D014178:Translocation, Genetic