Observations on T-cell sub-populations in type II reactions.
15 cases each of Type II Reaction, LL and TT Leprosy and 50 endemic controls were studied for phenotypic markers T2, T4 and T8 by 2 step immunoperoxidase technique. There was statistically significant increase in T4 (helper) cells in Type II Reaction. There was also a decrease in T8 cells but this was not statistically significant.
Kalyanasundaram
K
K
Division of Laboratories, Central Leprosy Teaching and Research Institute, Chengalpattu, Tamil, Nadu.
Elangeswaran
N
N
Bhatia
V N
VN
Thiagarajan
M
M
Sirumban
P
P
D000328:Adult; D000911:Antibodies, Monoclonal; D004359:Drug Therapy, Combination; D006801:Humans; D007124:Immunoenzyme Techniques; D015440:Leprosy, Lepromatous / Q000188:drug therapy / Q000276:immunology*; D015441:Leprosy, Tuberculoid / Q000188:drug therapy / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*
D000911:Antibodies, Monoclonal