title: Correlation of nitrogen metabolism with biosurfactant production by Pseudomonas aeruginosa.
abstract: A direct relationship between increased glutamine synthetase activity and enhanced biosurfactant production was found in Pseudomonas aeruginosa grown in nitrate and Proteose Peptone media. A chloramphenicol-tolerant strain showed a twofold increase in biosurfactant production and glutamine synthetase activity. Increased ammonium and glutamine concentrations repressed both phenomena.
authors.affiliation: Biotechnology Research Institute, National Research Council, Montreal, Quebec, Canada.
authors.forename: C N
authors.initials: CN
authors.lastname: Mulligan
authors.forename: B F
authors.initials: BF
authors.lastname: Gibbs
mesh_terms: D000362:Agar; D005969:Glutamate Dehydrogenase / Q000378:metabolism; D005970:Glutamate Synthase / Q000378:metabolism; D009584:Nitrogen / Q000378:metabolism*; D011550:Pseudomonas aeruginosa / Q000378:metabolism*; D013501:Surface-Active Agents / Q000378:metabolism*; D000637:Transaminases / Q000378:metabolism*
chemical_list: D013501:Surface-Active Agents; D000362:Agar; D005970:Glutamate Synthase; D005969:Glutamate Dehydrogenase; D000637:Transaminases; C020656:glutamine-pyruvate aminotransferase; D009584:Nitrogen