Carboxyalkyl dipeptides with atrial natriuretic factor potentiating and antihypertensive activity.
Haslanger
M F
MF
Department of Chemical Research, Schering-Plough Research, Bloomfield, New Jersey 07003.
Sybertz
E J
EJ
Neustadt
B R
BR
Smith
E M
EM
Nechuta
T L
TL
Berger
J
J
D000478:Alkylation; D000818:Animals; D009320:Atrial Natriuretic Factor / Q000097:blood / Q000494:pharmacology* / Q000627:therapeutic use; D001794:Blood Pressure / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D004151:Dipeptides / Q000138:chemical synthesis / Q000494:pharmacology* / Q000627:therapeutic use; D004357:Drug Synergism; D006207:Half-Life; D006973:Hypertension / Q000188:drug therapy*; D007668:Kidney / Q000201:enzymology; D015260:Neprilysin / Q000037:antagonists & inhibitors* / Q000378:metabolism; D011817:Rabbits; D051381:Rats
D004151:Dipeptides; D009320:Atrial Natriuretic Factor; D015260:Neprilysin