Refined sublocalization of the human gene encoding the beta subunit of the S100 protein (S100B) and confirmation of a subtle t(9;21) translocation using in situ hybridization.
The gene which encodes the beta subunit of the S100 protein was mapped to 21q22.2----q22.3 by in situ hybridization. Concurrently, a subtle translocation involving this region of chromosome 21 and 9q34 was confirmed.
Duncan
A M
AM
Department of Pathology, Queen's University, Kingston, Ontario, Canada.
Higgins
J
J
Dunn
R J
RJ
Allore
R
R
Marks
A
A
D002874:Chromosome Mapping; D002891:Chromosomes, Human, Pair 21; D002899:Chromosomes, Human, Pair 9; D003001:Cloning, Molecular; D004247:DNA; D004314:Down Syndrome / Q000235:genetics; D006801:Humans; D007223:Infant; D007621:Karyotyping; D008297:Male; D009693:Nucleic Acid Hybridization; D009418:S100 Proteins / Q000235:genetics*; D014178:Translocation, Genetic
D009418:S100 Proteins; D004247:DNA