title: [Inbreeding coefficient in carriers of Schistosoma mansoni].
abstract: The coefficient of inbreeding (for Wright) was studied in Catolândia, in the state of Bahia, Brazil, an area considered hyperendemic for manson schistosomiasis in a population of 1,130 inhabitants. The coefficient of inbreeding was estimated for 1,123 individuals it was classified as f greater than 0 in 13.2% (n = 148). In the hepatosplenic group the frequency of f greater than 0 was 26.8%, and in the hepatointestinal group the frequency was 12.5%. The frequency of the hepatosplenic diagnosis in whites who were f = 0 did not differ from that which was observed in the negroid group. These verifications were confirmed by the Woolf's test; the relative risk of the whites, f greater than 0 in acquiring hepatosplenic schistosomiasis was 14.1. These observations reinforce the influence of the genetic component in the development of the hepatosplenic form of the mansons schistosomiasis.
authors.forename: J
authors.initials: J
authors.lastname: Tavares-Neto
authors.forename: A
authors.initials: A
authors.lastname: Prata
mesh_terms: D001938:Brazil / Q000208:ethnology; D002353:Carrier State; D003241:Consanguinity; D006801:Humans; D008109:Liver Diseases, Parasitic / Q000208:ethnology / Q000635:transmission*; D012555:Schistosomiasis mansoni / Q000208:ethnology / Q000635:transmission*; D013158:Splenic Diseases / Q000208:ethnology / Q000235:genetics*
vernacular_title: Coeficiente de endocruzamento em portadores de esquistossomose mansônica.