Comparison of the effects of NaF and CaF2 on rat gastric mucosa. A light-, scanning- and transmission electron microscopic study.
Rat stomachs were studied after intragastrically administered, repeated doses of 0.1 N HCl, 100 mmol/l NaF, 50 mmol/l CaF2 in 0.1 N HCl, respectively. NaF produced extensive desquamation and cell injury, while CaF2 caused some desquamation and a slight decrease in secretory activity as revealed by light microscopic, SEM and TEM examinations.
Kertész
P
P
Department of Conservative Dentistry, Semmelweis University Medical School, Budapest, Hungary.
Kerényi
T
T
Kulka
J
J
Bánóczy
J
J
D000818:Animals; D002124:Calcium Fluoride / Q000494:pharmacology*; D005260:Female; D005753:Gastric Mucosa / Q000187:drug effects / Q000648:ultrastructure*; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D051381:Rats; D011919:Rats, Inbred Strains; D012969:Sodium Fluoride / Q000494:pharmacology*
D012969:Sodium Fluoride; D002124:Calcium Fluoride