title: Transcriptional regulation of cell division genes in Escherichia coli.
abstract: The complete Escherichia coli ftsQ coding sequence, together with part of the ftsA coding sequence, has been cloned upstream of the lacZ open reading frame in a lambda-vector (lambda JFL100). Cells which are lysogenic for lambda JFL100 transcribe the cloned lacZ from promoter(s) within the ftsQ and ftsA sequences. The level of beta-galactosidase produced is dependent on growth rate (and/or cell size) and is derepressed in an ftsA-deficient mutant. Transcription during the cell cycle is restricted to the time of cell division.
authors.affiliation: Department of Molecular Biology, University of Edinburgh, UK.
authors.forename: S J
authors.initials: SJ
authors.lastname: Dewar
authors.forename: V
authors.initials: V
authors.lastname: Kagan-Zur
authors.forename: K J
authors.initials: KJ
authors.lastname: Begg
authors.forename: W D
authors.initials: WD
authors.lastname: Donachie
mesh_terms: D002455:Cell Division; D004261:DNA Replication; D004926:Escherichia coli / Q000235:genetics*; D015964:Gene Expression Regulation, Bacterial; D005809:Genes, Regulator; D012097:Repressor Proteins / Q000502:physiology; D015183:Restriction Mapping; D014158:Transcription, Genetic; D001616:beta-Galactosidase / Q000096:biosynthesis
chemical_list: D012097:Repressor Proteins; D001616:beta-Galactosidase