title: Transcatheter arterial chemoembolization for hepatocellular carcinoma.
abstract: Hepatocellular carcinoma (HCC) was treated with transcatheter arterial chemoembolization (TACE) in a sample of 129 patients. The cumulative survival rate was 49% at 1 year and 22% at 2 years. The median survival time was 11.9 months. The survival rates at 1 year of 84 patients in Child's group A and 27 in Child's group B were 56% and 40%; out of 52 HCC patients with portal vein patent and 77 with portal vein invasion 75% and 40% survived, and the 1-year survival rates for 33 HCC patients with capsule intact, 14 with capsule broken and 82 with no capsule were 85%, 65% and 40% respectively. From the above results there were statistically significant differences in survival time in those with good clinical performance status by Child's classification, those showing patency of the portal vein and those where the capsule was present. Therefore, we would like to recommend, TACE of HCC in well-selected patients presenting with good clinical status, patency of the portal vein and without broken capsule, in order to achieve better clinical results.
authors.affiliation: Department of Radiology, Veterans General Hospital-Taichung, Taichung Taiwan.
authors.forename: C F
authors.initials: CF
authors.lastname: Yang
authors.forename: Y Z
authors.initials: YZ
authors.lastname: Ho
authors.forename: J M
authors.initials: JM
authors.lastname: Chang
authors.forename: R H
authors.initials: RH
authors.lastname: Chiang
authors.forename: K H
authors.initials: KH
authors.lastname: Lai
authors.forename: S D
authors.initials: SD
authors.lastname: Lee
authors.forename: Y T
authors.initials: YT
authors.lastname: Tsai
authors.forename: W Y
authors.initials: WY
authors.lastname: Lui
authors.forename: T J
authors.initials: TJ
authors.lastname: Liu
authors.forename: G H
authors.initials: GH
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000401:mortality / Q000628:therapy*; D002406:Catheterization, Peripheral; D004317:Doxorubicin / Q000008:administration & dosage*; D004621:Embolization, Therapeutic; D005260:Female; D006499:Hepatic Artery; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage*
chemical_list: D008937:Mitomycins; D016685:Mitomycin; D004317:Doxorubicin