[Clinicopathologic investigation of 63 cases of pituitary adenoma--special reference to immunohistochemical study of hormone production].
We have referred 63 cases of pituitary adenoma during past 10 years at department pathology of Hokkaido University Hospital. The mean age at diagnosis was 38 years, with a range from 13 to 73 years. 35 patients complained of non-hormonal sign (head ache, disturbance of vision, disturbance of consciousness, fatigability), 32 patients presented with hormonal sign (acromegaly, troubles of menstruation, galactorrhoea, cushing syndrome) and 7 patients had both signs. Immunohistochemically, GH cell adenoma was 16 cases, Prolactine cell adenoma was 11 cases, ACTH cell adenoma was 4 cases, Non-functioning adenoma was 19 cases and Mixed type was 10 cases.
Inoue
K
K
Department of Pathology, Hokkaido University Hospital.
Fujita
M
M
Nojima
T
T
Takebayashi
K
K
Sugimoto
N
N
Tokuda
K
K
Abe
H
H
D000236:Adenoma / Q000145:classification / Q000378:metabolism* / Q000473:pathology; D000293:Adolescent; D000324:Adrenocorticotropic Hormone / Q000032:analysis* / Q000096:biosynthesis; D000328:Adult; D000368:Aged; D005260:Female; D013006:Growth Hormone / Q000032:analysis* / Q000096:biosynthesis; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000145:classification / Q000378:metabolism* / Q000473:pathology; D011388:Prolactin / Q000032:analysis* / Q000096:biosynthesis
D000324:Adrenocorticotropic Hormone; D011388:Prolactin; D013006:Growth Hormone