Somatosensory evoked potentials in Huntington's disease--studies with paired stimulation.
The somatosensory evoked potentials (SEPs) and recovery functions of the SEP with paired stimulation were studied in patients with Huntington's disease (HD). A significant decrease in amplitude of the SEP was observed in 4 of the 5 patients. In addition, with paired stimulation, the second SEP amplitudes were normalized at intervals of about 10 ms. These findings possibly suggest that functional block rather than organic change in the thalamus may play an important role in the reduction in SEP amplitude in HD.
Kanda
F
F
Jinnai
K
K
Takahashi
K
K
Abe
H
H
Yasuda
M
M
Tada
K
K
Fujita
T
T
D000328:Adult; D000368:Aged; D004558:Electric Stimulation; D005073:Evoked Potentials, Somatosensory; D006801:Humans; D006816:Huntington Disease / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged