Immunity to rotaviruses.
A potent, multivalent, serotype-specific RV vaccine and improved tests for measuring vaccine potency would help eliminate the necessity to pretest for vaccine efficacy in every country selected for its deployment. Until then, the need will continue for vaccine trials in various countries because the pathogenesis and epidemiology of RV and RV serotypes differ between and within countries. Although RV vaccinology is complex, it has forged ahead of our knowledge of RV immunopathogenesis and epidemiology.
Edelman
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Flores
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Kapikian
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D000818:Animals; D006801:Humans; D007109:Immunity; D012401:Rotavirus / Q000145:classification / Q000276:immunology*; D012400:Rotavirus Infections / Q000209:etiology / Q000276:immunology / Q000517:prevention & control; D014765:Viral Vaccines / Q000008:administration & dosage / Q000302:isolation & purification
D014765:Viral Vaccines