title: Electrochemical and thermal studies of some quaternary benzo(c) phenanthridine alkaloids.
abstract: The conditions of the electrochemical reduction and oxidation as well as those of thermal demethylation of quaternary benzo(c)-phenanthridine alkaloids namely chelerythrine (1), sanguinarine (2), and fagaronine (3) were studied. Differences in their electrochemical and thermal behavior are correlated with the results obtained from biotransformation studies with liver microsomal fraction.
authors.forename: J
authors.initials: J
authors.lastname: Lasovský
authors.forename: D
authors.initials: D
authors.lastname: Walterová
authors.forename: J
authors.initials: J
authors.lastname: Smidrkal
authors.forename: R
authors.initials: R
authors.lastname: Pastorek
authors.forename: V
authors.initials: V
authors.lastname: Simánek
mesh_terms: D000470:Alkaloids / Q000032:analysis*; D053119:Benzophenanthridines; D001711:Biotransformation; D004563:Electrochemistry; D007546:Isoquinolines; D009153:Mutagens; D010084:Oxidation-Reduction; D010616:Phenanthrenes / Q000032:analysis*; D010617:Phenanthridines / Q000032:analysis; D010946:Plants, Medicinal
chemical_list: D000470:Alkaloids; D053119:Benzophenanthridines; D007546:Isoquinolines; D009153:Mutagens; D010616:Phenanthrenes; D010617:Phenanthridines; C002066:fagaronine; C005705:sanguinarine; C016299:chelerythrine