title: [Diphosphonates. Current trends and therapeutic prospects].
abstract: Diphosphonates are compounds characterized by a P-C-P bond. They are thus analogs of pyrophosphate and can be useful for treating several bone diseases. The authors synthetically review the mechanism of action of these drugs and their most important clinical applications. The authors finally mention the interesting therapeutic possibilities deriving from the development of new members of this class.
authors.forename: P
authors.initials: P
authors.lastname: Raviolo
authors.forename: G
authors.initials: G
authors.lastname: Galvagno
authors.forename: V
authors.initials: V
authors.lastname: Biarese
authors.forename: P
authors.initials: P
authors.lastname: Lovisetto
mesh_terms: D001847:Bone Diseases / Q000188:drug therapy*; D001859:Bone Neoplasms / Q000188:drug therapy; D002114:Calcinosis / Q000188:drug therapy; D004164:Diphosphonates / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006801:Humans; D006961:Hyperparathyroidism / Q000188:drug therapy; D009999:Ossification, Heterotopic / Q000188:drug therapy; D010001:Osteitis Deformans / Q000188:drug therapy; D010024:Osteoporosis / Q000188:drug therapy
chemical_list: D004164:Diphosphonates
vernacular_title: I difosfonati. Attualità e prospettive terapeutiche.