title: [Ultrastructural aspects in the development of the human heart. II. The endocrine cells of the embryonic heart].
abstract: Electronmicroscopic studies performed on atrial and ventricular tissue fragments from 9 human embryos, 8 to 15 weeks old, showed that in certain myocardiocytes, especially in the atrial ones, from the 10 weeks old embryos, there appear granules of secretion, very similar in morphology with those from adults, which had been demonstrated to contain the atrial natriuretic factor. The precocious appearance of this peptide represents a functional adaptation by which the embryo attempts at counterbalancing the actions of renin and angiotensin from the maternal circulation.
authors.forename: C
authors.initials: C
authors.lastname: Cotrutz
authors.forename: M
authors.initials: M
authors.lastname: Constantinov
authors.forename: C
authors.initials: C
authors.lastname: Ionescu
authors.forename: C
authors.initials: C
authors.lastname: Cotrutz
authors.forename: M
authors.initials: M
authors.lastname: Moraru
authors.forename: G
authors.initials: G
authors.lastname: Marta
mesh_terms: D009320:Atrial Natriuretic Factor / Q000378:metabolism; D003584:Cytological Techniques; D004702:Endocrine Glands / Q000196:embryology / Q000378:metabolism / Q000648:ultrastructure*; D005865:Gestational Age; D006321:Heart / Q000196:embryology*; D006651:Histocytochemistry; D006801:Humans; D008854:Microscopy, Electron; D009206:Myocardium / Q000378:metabolism / Q000648:ultrastructure*
chemical_list: D009320:Atrial Natriuretic Factor
vernacular_title: Aspects ultrastructuraux dans le développement du coeur humain. II. Les cellules endocrines du coeur embryonnaire.