Experimental study on the treatment of oral precancerous lesion--short and long term effect of tablet Anticancer II.
This paper reports the experimental study on the treatment of oral precancerous lesion by use of a drug composed of six kinds of Chinese herb medicines, the Anticancer II Tablet. An animal model of lesions with epithelial dysplasia is first produced in cheek pouches of Syrian golden hamsters with a carcinogen, and the drug is then given thrice a week for 12 weeks. The short- and long-term results are good as assessed by comparison with controls in gross and microscopic examination and Interactive Image Analysis System.
Zhang
K H
KH
Research Institute of Stomatology, School of Stomatology, Beijing Medical University, China.
Xie
J F
JF
D015127:9,10-Dimethyl-1,2-benzanthracene; D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure; D002471:Cell Transformation, Neoplastic; D006224:Cricetinae; D004273:DNA, Neoplasm / Q000032:analysis; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D007091:Image Processing, Computer-Assisted; D008297:Male; D008647:Mesocricetus; D009062:Mouth Neoplasms / Q000188:drug therapy* / Q000473:pathology; D011230:Precancerous Conditions / Q000188:drug therapy* / Q000473:pathology; D011897:Random Allocation; D013997:Time Factors
D004273:DNA, Neoplasm; D004365:Drugs, Chinese Herbal; D015127:9,10-Dimethyl-1,2-benzanthracene