Simultaneous presence of platelet activating factor, leukotriene B4, prostaglandin F1 alpha and F2 alpha in the supernatant of human neutrophils treated with phospholipase A2 of human monocytes.
The simultaneous presence of platelet-activating factor, leukotriene B4, prostaglandin F1 alpha and F2 alpha are detectable in the supernatant of human neutrophil granulocytes treated with phospholipase A2 of human monocytes. This enzyme is suspected to play an important role in the pathomechanism of inflammation.
Sipka
S
S
3rd Department of Internal Medicine, Medical School of Debrecen.
Dinya
Z
Z
Gergely
P
P
Farkas
T
T
Szegedi
G
G
D015237:Dinoprost / Q000378:metabolism*; D006801:Humans; D007975:Leukotriene B4 / Q000378:metabolism*; D008970:Molecular Weight; D009000:Monocytes / Q000201:enzymology*; D009504:Neutrophils / Q000187:drug effects*; D010740:Phospholipases / Q000494:pharmacology*; D010741:Phospholipases A / Q000494:pharmacology*; D054467:Phospholipases A2; D010972:Platelet Activating Factor / Q000378:metabolism*; D011460:Prostaglandins F / Q000378:metabolism*
D010972:Platelet Activating Factor; D011460:Prostaglandins F; D007975:Leukotriene B4; D015237:Dinoprost; D010740:Phospholipases; D010741:Phospholipases A; D054467:Phospholipases A2; C100006:prostaglandin F1