title: [Interactions between the immune system and the neuroendocrine system. Implications of the hypothalamo-hypophyseal-adrenal axis].
abstract: The immune and neuroendocrine systems are now recognized to be linked and involved in bidirectional communication. That interrelationship involves shared usage of common signal molecules and their receptors. The Immune System and its products can modulate neuroendocrine functions and neuroendocrine peptides and hormones can affect important immunological parameters. Specifically, this article review the evidence for immune-neuroendocrine interactions in relation to the Hypothalamic-Pituitary-Adrenocortical axis. Neuroendocrine-immune interactions appears to play an important role in psychosocial influences on immunologically resisted and mediated diseases.
authors.forename: C
authors.initials: C
authors.lastname: Sandi
authors.forename: M A
authors.initials: MA
authors.lastname: Castro-Alamancos
authors.forename: J C
authors.initials: JC
authors.lastname: Cambronero
authors.forename: C
authors.initials: C
authors.lastname: Bailón
authors.forename: C
authors.initials: C
authors.lastname: Guaza
authors.forename: J
authors.initials: J
authors.lastname: Borrel
mesh_terms: D003346:Corticotropin-Releasing Hormone / Q000096:biosynthesis / Q000502:physiology; D005938:Glucocorticoids / Q000502:physiology; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology*; D007107:Immune System / Q000502:physiology*; D007375:Interleukin-1 / Q000502:physiology; D008214:Lymphocytes / Q000502:physiology; D010913:Pituitary-Adrenal System / Q000502:physiology*; D013315:Stress, Psychological / Q000503:physiopathology*; D001615:beta-Endorphin / Q000096:biosynthesis / Q000502:physiology
chemical_list: D005938:Glucocorticoids; D007375:Interleukin-1; D001615:beta-Endorphin; D003346:Corticotropin-Releasing Hormone
vernacular_title: Interacciones entre el sistema inmunitario y el sistema neuroendocrino. Implicaciones del eje hipotálamo-hipófisis-adrenal.