title: [Treatment of critical pulmonary valvular stenoses in newborn infants using percutaneous valvuloplasty. Study of 28 cases].
abstract: Twenty-eight neonates aged 1 to 21 days with critical pulmonic stenosis were treated by percutaneous valvotomy consisting of balloon dilatation of the stenotic valve by percutaneous catheterization. The right ventricular systolic pressure (RVP) was either the same or higher than the systemic pressure in all cases but 3. In those it was somewhat lower (80%) than the left ventricular systolic pressure (LVP) so that, on the whole, the RVP/LVP ratio, here called rP ranged from 0.8 to 2 (m = 1.41 +/- 0.36). The procedure failed 5 times because of failure to introduce the balloon through the valve (4 cases) or because of an accident (1 case). All failures occurred during the initial phase of our experience with this procedure as the last 20 trials were successful. The procedure was inefficacious in 3 cases (13%) but immediately successful in the other 20 (87%) with a drop in the mean rP to 0.59 +/- 0.17. During the follow-up period, one neonate continued to present with an important degree of cyanosis, due to a poor right ventricular compliance. He had to be operated on. Pulmonic stenosis reappeared in 6 cases who underwent for a second time a percutaneous valvotomy. The procedure was successful in 3 and failed in 3 who eventually required surgery. Overall, the satisfactory results observed after the procedure persisted over time in 13 cases. In conclusion, interventional catheterization has become almost always possible in neonates with critical pulmonic stenosis. If performed under vigorously controlled conditions including an infusion of prostaglandin E1 in cases with severe cyanosis and the use of large diameter balloons, this method is relatively safe and generally efficacious since in 70% of cases it circumvents the need for surgery.
authors.affiliation: Département de Pédiatrie, Hôpital Necker-Enfants-Malades, Paris.
authors.forename: S
authors.initials: S
authors.lastname: Guarnera
authors.forename: J F
authors.initials: JF
authors.lastname: Piechaud
authors.forename: J
authors.initials: J
authors.lastname: Kachaner
authors.forename: J
authors.initials: J
authors.lastname: Le Bidois
authors.forename: L
authors.initials: L
authors.lastname: Cohen
authors.forename: D
authors.initials: D
authors.lastname: Sidi
authors.forename: E
authors.initials: E
authors.lastname: Villain
mesh_terms: D000800:Angioplasty, Balloon; D002404:Catheterization; D005069:Evaluation Studies as Topic; D006801:Humans; D007231:Infant, Newborn; D011666:Pulmonary Valve Stenosis / Q000628:therapy*
vernacular_title: Traitement des sténoses valvulaires pulmonaires critiques du nouveau-né par valvuloplastie percutanée. Etude de 28 cas.