[The suppression of rapid local surface oscillations in human erythrocytes slows and weakens their adhesion to glass].
Rapid local oscillations of the erythrocyte surface with amplitude 200-300 nm are decreased by 10 times following addition of wheat germ agglutinin (10(-77) M). In this case the rate of erythrocyte adhesion to the cover glass is delayed approximately by 3-9 times. The total suppression of erythrocyte surface oscillations occurs in hypo-osmic solution or in a 0.01% solution of glutaraldehyde. It coincides with a two-fold decrease of erythrocyte adhesivity to the glass. It is suggested that the rapid erythrocyte surface oscillations may control the rate of cell adhesion to the substrate.
Grinfel'dt
M G
MG
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A Iu
AIu
Levin
S V
SV
D000117:Acetylglucosamine / Q000494:pharmacology; D002448:Cell Adhesion / Q000187:drug effects / Q000502:physiology; D003864:Depression, Chemical; D004912:Erythrocytes / Q000187:drug effects / Q000502:physiology*; D005898:Glass; D005976:Glutaral / Q000494:pharmacology; D006801:Humans; D012709:Serum Albumin / Q000494:pharmacology; D013499:Surface Properties; D013997:Time Factors; D014909:Wheat Germ Agglutinins / Q000494:pharmacology
D012709:Serum Albumin; D014909:Wheat Germ Agglutinins; D005976:Glutaral; D000117:Acetylglucosamine
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