[Radiotherapy of seminoma in the 2d stage].
The radiotherapy of seminoma in second stage, i.e. with lumbo-aortic lymph nodes metastases, is debated. Some authors restrict the radiation therapy to under-diaphragmatic lymph nodes, with saving chemotherapy by platinum, only in relapses; for others, the radiotherapy is eligible for all, under and over-diaphragmatic lymph nodes. The author analyzed 30 patients with seminoma, 26 in state IIA and 4 in stage IIB; all patients was treated with extended irradiation. The total survival was 96%. There is not long-term radiation injury. With regards to this results, the author think that the extended radiotherapy still represent the first treatment to patients with seminoma in stage II, in consideration of potential damage of chemotherapy, and percentage of 20/25% relapses over the diaphragm.
Martinelli
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Divisione di Radioterapia, U.S.L. n. 4, Parma.
D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D004407:Dysgerminoma / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy*; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D011867:Radioisotope Teletherapy; D011879:Radiotherapy Dosage; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy*; D013997:Time Factors
D003037:Cobalt Radioisotopes
La radioterapia dei seminomi in secondo stadio.