Effects of the putative phospholipid precursors, inositol, choline, serine and ethanolamine, on formation and expansion of rabbit blastocysts in vitro.
Rabbit morulae were cultured to blastocysts in various concentrations of the potential phospholipid precursors, myo-inositol, choline, serine and ethanolamine. Serine (20-2500 microM) had a significant stimulatory effect on blastocyst formation and blastocyst expansion and inositol (3-375 microM) had a significant stimulatory effect on blastocyst expansion. There was no significant stimulatory effect of choline or ethanolamine.
Kane
M T
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Department of Physiology, University College, Galway, Ireland.
D000818:Animals; D001755:Blastocyst / Q000187:drug effects / Q000502:physiology*; D002794:Choline / Q000494:pharmacology; D003470:Culture Media; D046508:Culture Techniques; D004305:Dose-Response Relationship, Drug; D019856:Ethanolamine; D004983:Ethanolamines / Q000494:pharmacology; D005260:Female; D007294:Inositol / Q000494:pharmacology; D010743:Phospholipids / Q000378:metabolism*; D011817:Rabbits; D012694:Serine / Q000494:pharmacology
D003470:Culture Media; D004983:Ethanolamines; D010743:Phospholipids; D012694:Serine; D007294:Inositol; D019856:Ethanolamine; D002794:Choline