title: [Granulomatous dermatitis caused by surfen in diabetics treated with Insulin-depot-S-Richter].
abstract: Two cases of local cutaneous reaction in diabetics treated with Insulin-depot-S-Richter are reported. Intracutaneous test and histological examination revealed that the granulomatous inflammation of the skin was due to surfen. Insulin-depot-S-Richter was changed to insulin preparation free from surfen (Monotard MC, Novo) and no further local reactions could be observed in the same patients.
authors.forename: G
authors.initials: G
authors.lastname: Jermendy
authors.forename: E
authors.initials: E
authors.lastname: Szabó
mesh_terms: D003692:Delayed-Action Preparations; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy*; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D005260:Female; D006099:Granuloma / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects*; D007328:Insulin / Q000008:administration & dosage* / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D014508:Urea / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*
chemical_list: D003692:Delayed-Action Preparations; D007004:Hypoglycemic Agents; D007328:Insulin; C010850:aminoquinuride; D014508:Urea
vernacular_title: Surfen okozta granulomás börgyulladás Insulin-depot-S-Richter terápia kapcsán.