[The effect of local administration of corticosteroids on the course and therapy of rosacea].
The results of the analysis of 446 patients (305 women and 141 men) with rosacea treated in the Medical cosmetologic section (Department of Dermatology, University Hospital Centre Zagreb) between 1985 and 1986 have been presented. The disease was more common among women than in men. (2.16:1). The duration, localization and clinical picture were typical. The histopathologic analysis was done in 9 patients. Among the 446 rosacea patients, 250 (56.1%) had prolonged therapy with powerful topical corticosteroids. The recommended treatment depended on the severity of the clinical picture consisting of usual local therapy and oral tetracyclines. In the group previously treated with topical corticosteroids, because of more severe clinical picture, tetracyclines were given more frequently (in the 35.6% of cases) than in the other group where the tetracyclines were given in 20.9%. The authors followed-up the duration and treatment success in 275 regularly controlled patients (in 164 with prolonged topical corticosteroid treatment and in 111 without previous corticosteroid treatment). In average, the patients without previous corticosteroid therapy were treated shorter and with better success in contrasts to patients with prolonged topical corticosteroid treatment. The results of the investigation indicate that rosacea patients should not be treated with topical corticosteroids.
Basta-Juzbasić
A
A
Dobrić
I
I
D000287:Administration, Topical; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage* / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012393:Rosacea / Q000188:drug therapy* / Q000473:pathology
D000305:Adrenal Cortex Hormones
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