Electrostimulation-induced fast-to-slow transitions of myosin light and heavy chains in rabbit fast-twitch muscle at the mRNA level.
Chronic low-frequency stimulation of rabbit fast-twitch muscle induces progressive increases in slow myosin light chain mRNAs followed by an increase in the slow myosin heavy chain HCI mRNA. Therefore, the effects of chronic stimulation are more pronounced in rabbit than in rat fast-twitch muscle. The latter responds mainly with a rearrangement of its fast isomyosin pattern.
Kirschbaum
B J
BJ
Fakultät für Biologie, Universität Konstanz, FRG.
Heilig
A
A
Härtner
K T
KT
Pette
D
D
D000818:Animals; D004558:Electric Stimulation; D004720:Endonucleases; D009119:Muscle Contraction; D009132:Muscles / Q000378:metabolism* / Q000502:physiology; D009218:Myosins / Q000235:genetics / Q000378:metabolism*; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000378:metabolism*; D011817:Rabbits; D015183:Restriction Mapping; D015719:Single-Strand Specific DNA and RNA Endonucleases; D013997:Time Factors
D012333:RNA, Messenger; D004720:Endonucleases; D015719:Single-Strand Specific DNA and RNA Endonucleases; D009218:Myosins