title: Investigation of varicella-zoster virus infection of lymphocytes by in situ hybridization.
abstract: Peripheral blood mononuclear cells harboring viral gene sequences were detected during primary varicella-zoster virus (VZV) infection of the human host and the strain 2 guinea pig by in situ hybridization with a 3H-labeled VZV DNA probe. Activated T lymphocytes were permissive for VZV infection at low frequency in vitro.
authors.affiliation: Department of Pediatrics, Stanford University School of Medicine, California 94305.
authors.forename: C M
authors.initials: CM
authors.lastname: Koropchak
authors.forename: S M
authors.initials: SM
authors.lastname: Solem
authors.forename: P S
authors.initials: PS
authors.lastname: Diaz
authors.forename: A M
authors.initials: AM
authors.lastname: Arvin
mesh_terms: D000818:Animals; D015342:DNA Probes; D004279:DNA, Viral / Q000032:analysis; D006168:Guinea Pigs; D006562:Herpes Zoster / Q000175:diagnosis*; D014645:Herpesvirus 3, Human / Q000235:genetics*; D006801:Humans; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000382:microbiology*; D009693:Nucleic Acid Hybridization; D013045:Species Specificity
chemical_list: D015342:DNA Probes; D004279:DNA, Viral