[The cAMP content and cAMP-dependent protein kinase activity in the brain of rabbits in the dynamics of moderate craniocerebral trauma].
An intracellular concentration of cAMP is a factor to define activity of cAMP-dependent protein kinases. Enzyme activity changes in cytosol and microsomal fractions from investigated brain's regions. Two-phase character of posttraumatic changes of A-kinases activity is shown. Linear dependence for microsomal fractions obtained from brain's hemispheres is observed between A-kinases activity and calculated equilibrium cAMP concentration in different time after experimental cranial trauma.
Kucherenko
S N
SN
Ostapenko
L I
LI
Vasil'ev
A N
AN
D000818:Animals; D001921:Brain / Q000378:metabolism*; D001923:Brain Chemistry; D001930:Brain Injuries / Q000378:metabolism*; D002462:Cell Membrane / Q000032:analysis / Q000378:metabolism; D000242:Cyclic AMP / Q000032:analysis / Q000378:metabolism*; D003600:Cytosol / Q000032:analysis / Q000378:metabolism; D008297:Male; D011494:Protein Kinases / Q000032:analysis / Q000378:metabolism*; D011817:Rabbits; D013997:Time Factors
D000242:Cyclic AMP; D011494:Protein Kinases
Soderzhanie tsAMF i aktivnost' tsAMF-zavisimykh proteinkinaz v golovnom mozge krolikov v dinamike legkoĭ cherepno-mozgovoĭ travmy.