[Comparative analysis of disorders of neuromuscular conduction in patients with botulism and Eaton-Lambert myasthenic syndrome].
The analysis of conduction at neuromuscular junctions was performed in 25 patients with botulism and 31 patients with Lambert-Iton syndrome. These groups showed apparent differences in mechanisms of recruitment and posttetanic facilitation of the neurotransmitter release. Prolonged stimulation with the rate of 6 imp/s in ischemic muscles pointed to essential differences in the mechanisms facilitating the transmitter release. These differences of neuromuscular conduction disorders in botulism and Lambert-Iton syndrome are supposedly connected with affliction of different mechanisms of conduction facilitation in the neuromuscular synapses.
Sanadze
A G
AG
Polikarpova
E V
EV
D001906:Botulism / Q000503:physiopathology*; D018288:Carcinoma, Small Cell / Q000150:complications / Q000503:physiopathology*; D004558:Electric Stimulation; D006225:Hand / Q000294:innervation; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000503:physiopathology*; D009132:Muscles / Q000294:innervation; D009157:Myasthenia Gravis / Q000150:complications / Q000503:physiopathology*; D009431:Neural Conduction; D009469:Neuromuscular Junction / Q000502:physiology*; D013577:Syndrome
Sravnitel'nyĭ analiz narusheniĭ nervno-myshechnoĭ peredachi u bol'nykh botulizmom i miastenicheskim sindromom Lamberta-Itona.