[Treatment of hemophilia in children].
Thanks to recent developments and evolution in prenatal diagnosis and early onset within the first year of life, hemophilia may now be considered a pathology of primarily pediatric interest. The treatment of hemophilia in children has furthermore undergone a number of changes that include 2 main events in therapy that have served to modify the quality of life of the hemophiliac. The first of these events regards blood products and the prevention of viral infections, hepatitis and HIV transmission. Prevention is based on various factors which include: donor selection, immunization, product testing and heat treatment of blood products. The second extremely important aspect of treatment in hemophilia is the concept of global assistance, which includes: the treatment of the bleeding episode itself, and an ongoing psycho-social support system. In this paper we suggest some practical treatment schedules for the therapy of bleeding episodes in addition to examining the severe side effects of HIV and Hepatitis viruses. The message which our paper attempts to transmit is that the hemophilic child must be ideally assisted in an exclusively pediatric environment.
Stucchi
C
C
Clinica Pediatrica I dell'Università di Milano, Italia.
Giovanniello
A
A
Dozzi
M
M
Careddu
P
P
Carnelli
V
V
D000163:Acquired Immunodeficiency Syndrome / Q000635:transmission*; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005169:Factor VIII / Q000037:antagonists & inhibitors / Q000276:immunology; D006467:Hemophilia A / Q000188:drug therapy / Q000276:immunology / Q000628:therapy*; D006509:Hepatitis B / Q000635:transmission*; D006526:Hepatitis C / Q000635:transmission*; D006525:Hepatitis, Viral, Human / Q000635:transmission*; D006699:Home Care Services; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000209:etiology*; D007223:Infant; D007231:Infant, Newborn; D011379:Prognosis; D065227:Transfusion Reaction
D005169:Factor VIII
Il trattamento dell'emofilia in età pediatrica.