title: Total lipodystrophy with heart failure and renal failure: report of a case.
abstract: A 38-year-old female was admitted to our hospital because of dyspnea. The diagnosis of total lipodystrophy was made by following findings: (1) gaunt appearance; (2) insulin-resistant diabetes mellitus; (3) hyperlipidemia; (4) fatty liver. Chest X-ray demonstrated cardiomegaly, pulmonary edema and pleural effusion. Echocardiogram was characterized by left ventricular hypertrophy with asymmetrical septal hypertrophy and left ventricular dysfunction. Renal biopsy revealed focal glomerulosclerosis. We reported a patient with total lipodystrophy combined with heart failure and renal failure, which have been rarely associated with the disease.
authors.affiliation: Second Department of Internal Medicine, Ehime University School of Medicine, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Ishii
authors.forename: M
authors.initials: M
authors.lastname: Abe
authors.forename: M
authors.initials: M
authors.lastname: Kubo
authors.forename: T
authors.initials: T
authors.lastname: Sumimoto
authors.forename: M
authors.initials: M
authors.lastname: Hamada
authors.forename: K
authors.initials: K
authors.lastname: Hiwada
authors.forename: T
authors.initials: T
authors.lastname: Kokubu
authors.forename: G
authors.initials: G
authors.lastname: Osawa
mesh_terms: D000328:Adult; D006332:Cardiomegaly / Q000150:complications* / Q000503:physiopathology; D004452:Echocardiography; D005234:Fatty Liver / Q000150:complications; D005260:Female; D005921:Glomerulonephritis; D005923:Glomerulosclerosis, Focal Segmental / Q000150:complications* / Q000473:pathology; D006801:Humans; D008060:Lipodystrophy / Q000150:complications* / Q000473:pathology