A total body hyperthermia animal model for pharmacological studies.
Toxic side effects are the main drawback in localized and total body hyperthermia for the treatment of tumours. This paper reports a total body hyperthermia animal model which may be used as an experimental tool in the search for conditions or drugs capable of inhibiting the toxic effects of hyperthermia.
de Feo
G
G
Institute of Pharmacology and Pharmacognosy, University of Rome La Sapienza, Italy.
Lisciani
R
R
Capezzone de Joannon
A
A
Mazzanti
G
G
Tolu
L
L
Pace
S
S
D000818:Animals; D001831:Body Temperature; D003643:Death; D005260:Female; D006979:Hyperthermia, Induced; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008954:Models, Biological; D012727:Sex Characteristics