title: Staged thrombolysis and percutaneous transluminal coronary angioplasty for unstable and postinfarction angina.
abstract: The precise timing of intravenous thrombolysis and coronary angioplasty continues to be evaluated for patients who have coronary thrombosis and unstable angina or postinfarction angina. Coronary angioplasty is effective for these patients but is associated with thromboembolic coronary occlusion in 24% to 29% of cases. After adjunctive intravenous thrombolysis and oral antiplatelet therapy to improve the success rate and to decrease the risk of acute occlusion, deferred angioplasty was successful in three patients with intracoronary thrombus and unstable angina or postinfarction angina. Staged thrombolysis and deferred angioplasty is feasible for selected patients with these acute coronary syndromes.
authors.affiliation: Mayo Clinic, Rochester, MN 55905.
authors.forename: D V
authors.initials: DV
authors.lastname: Hurley
authors.forename: D R
authors.initials: DR
authors.lastname: Bresnahan
authors.forename: D R
authors.initials: DR
authors.lastname: Holmes
mesh_terms: D000328:Adult; D000787:Angina Pectoris / Q000188:drug therapy / Q000209:etiology / Q000628:therapy*; D000800:Angioplasty, Balloon; D003327:Coronary Disease / Q000628:therapy*; D003328:Coronary Thrombosis / Q000150:complications / Q000188:drug therapy / Q000628:therapy*; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D005343:Fibrinolytic Agents