title: An in vitro study of the antibacterial and antifungal properties of an irreversible hydrocolloid impression material impregnated with disinfectant.
abstract: The difficulties associated with the disinfection of alginate (irreversible hydrocolloid) materials have resulted in the development of an irreversible hydrocolloid impression material impregnated with an antimicrobial compound, didecyldimethyl ammonium chloride. This investigation assessed the antibacterial and antifungal properties in vitro of this innovative irreversible hydrocolloid material by using the agar well technique. The microorganisms used were Pseudomonas aeruginosa, Streptococcus mutans, Streptococcus sanguis, Lactobacillus odontolyticus rodriguez, Actinomyces odontolyticus, mixed salivary organisms, and Candida albicans. The results showed an absence of activity against Pseudomonas aeruginosa. Varying degrees of antibacterial activity were exhibited against the other microorganisms. It is concluded that it is not know whether the limited antibacterial and antifungal effect demonstrated in this study is sufficient to prevent bacterial and fungal colonization of the impression surface in the mouth during clinical practice.
authors.affiliation: Department of Oral Pathology, University of Birmingham, Dental School, England.
authors.forename: R S
authors.initials: RS
authors.lastname: Tobias
authors.forename: R M
authors.initials: RM
authors.lastname: Browne
authors.forename: C A
authors.initials: CA
authors.lastname: Wilson
mesh_terms: D000190:Actinomyces / Q000187:drug effects; D000464:Alginates / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D002175:Candida / Q000187:drug effects*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003102:Colloids / Q000494:pharmacology*; D004202:Disinfectants / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D007778:Lactobacillus / Q000187:drug effects; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D000644:Quaternary Ammonium Compounds / Q000008:administration & dosage / Q000494:pharmacology*; D012463:Saliva / Q000382:microbiology; D013295:Streptococcus mutans / Q000187:drug effects; D013298:Streptococcus sanguis / Q000187:drug effects; D013997:Time Factors
chemical_list: D000464:Alginates; C062271:Blueprint Asept; D003102:Colloids; D004202:Disinfectants; D000644:Quaternary Ammonium Compounds; C027118:didecyldimethylammonium