Platelet activation in outpatients undergoing esophagogastroduodenoscopy.
To evaluate the influence of emotional stress on platelet function, we have measured by radio-immunoassay in plasma two platelet-secreted proteins, beta-thromboglobulin and platelet factor 4, in a series of outpatients undergoing esophagogastroduodenoscopy for upper digestive complaints. The plasma levels of beta-thromboglobulin and platelet factor 4, determined just before the instrumental examination, were significantly more elevated as compared to basal values, checked a week later. These results provide evidence of enhanced in vivo platelet release reaction during emotional stress.
Sagripanti
A
A
Ferdeghini
M
M
Pinori
E
E
Polloni
A
A
Bianchi
R
R
Materazzi
F
F
D000328:Adult; D004384:Duodenoscopy; D004945:Esophagoscopy; D005260:Female; D005773:Gastroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation; D010978:Platelet Factor 4 / Q000032:analysis; D011863:Radioimmunoassay; D013315:Stress, Psychological / Q000097:blood*; D001620:beta-Thromboglobulin / Q000032:analysis
D001620:beta-Thromboglobulin; D010978:Platelet Factor 4