title: [Visual motor coordination of AIDS patients, HIV-positive asymptomatic probands and healthy persons during video-tracking].
abstract: Here we investigated the applicability of a computer-aided video-tracking as a method for evaluating potential deficits of neural information processing in patients with AIDS and those showing only positive HIV-seroreactivity. Video-tracking was accompanied with a simultaneous recording of EEG. Eight HIV-positive asymptomatic volunteers and eight AIDS-patients with cerebral manifestation of the disease participated in the pilot study. Two groups of eight normals each served as a control. Video-tracking performance of the HIV-positive volunteers and AIDS-patients significantly differed (p less than 0.05) from those of the healthy volunteers. Although the AIDS-patients' performance tended to be worse than that of the HIV-group, this difference was not significant. Power spectrum analysis of the EEG-data indicated that the diminished performance of the two test groups (AIDS and HIV-positives), accompanied by an increased spectral power across the entire frequency range measured in the study, could be an expression of an enhanced synchronization in cortical neuronal networks. The synchronization in turn could be a sign of possible organic brain damage resulting from HIV-infection. In conclusion, we suppose that video-tracking measures parameters which may indicate early deficits of information processing in CNS.
authors.affiliation: Abteilung für Klinische Neurophysiologie, Freien Universität, Berlin.
authors.forename: M L
authors.initials: ML
authors.lastname: Hansen
authors.forename: H
authors.initials: H
authors.lastname: Henkes
authors.forename: G
authors.initials: G
authors.lastname: Scholz
authors.forename: K
authors.initials: K
authors.lastname: Terstegge
authors.forename: S
authors.initials: S
authors.lastname: Kubicki
authors.forename: H
authors.initials: H
authors.lastname: Ott
authors.forename: W
authors.initials: W
authors.lastname: Röske
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000503:physiopathology*; D000328:Adult; D001921:Brain / Q000503:physiopathology*; D004569:Electroencephalography; D005260:Female; D006679:HIV Seropositivity / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008838:Microcomputers; D008875:Middle Aged; D011597:Psychomotor Performance; D012984:Software
vernacular_title: Visuomotorische Koordinationsleistung von AIDS-Patienten, HIV-positiven asymptomatischen Probanden und Gesunden im Videotracking.