title: Farber's lipogranulomatosis in siblings: light and electron microscopic studies.
abstract: Two cases of Farber's lipogranulomatosis in siblings are reported. The clinical features included contractures of the limbs with swelling of the joints and subcutaneous nodules and erythematous infiltrated plaques. On histology there were many large foam cells in the dermis, and electron microscopy showed numerous large cells with round cytoplasmic lamellar and microtubular bodies.
authors.affiliation: Department of Dermatology, Osaka City University Medical School, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Chanoki
authors.forename: M
authors.initials: M
authors.lastname: Ishii
authors.forename: K
authors.initials: K
authors.lastname: Fukai
authors.forename: H
authors.initials: H
authors.lastname: Kobayashi
authors.forename: T
authors.initials: T
authors.lastname: Hamada
authors.forename: K
authors.initials: K
authors.lastname: Murakami
authors.forename: A
authors.initials: A
authors.lastname: Tanaka
mesh_terms: D002675:Child, Preschool; D003286:Contracture / Q000473:pathology; D004890:Erythema / Q000473:pathology; D005121:Extremities; D005260:Female; D005487:Foam Cells / Q000648:ultrastructure; D006801:Humans; D007223:Infant; D008297:Male; D008854:Microscopy, Electron; D012867:Skin / Q000473:pathology; D013106:Sphingolipidoses / Q000235:genetics* / Q000473:pathology