Studies on maternally derived antibodies to Aujeszky's disease virus in piglets born to naturally or experimentally infected sows.
The concentration of maternally derived antibodies to Aujeszky's disease virus was compared in 10 litters born to infected sows. Four sows had been naturally infected and six were experimentally infected. Both IgG and IgM were present in piglet sera during the first days of life. IgM antibodies went rapidly to undetectable levels; IgG persisted much longer. The duration was dependent upon the original concentration. There was a clear relationship between the clinical disease experienced by the sow and the titre of antibodies in serum and colostrum; sows which had been naturally infected or experimentally infected with a highly virulent strain passed onto their litters a high amount of specific antibodies while sows which after experimental infection presented only mild clinical signs had very low titres of neutralizing antibodies and their litters were virtually devoid of specific antibodies at 3 weeks after birth. A return to detectable levels of IgM was noticed in some litters at around 9 weeks postcolostrum intake suggesting a development of a specific immune response.
Iglesias
G
G
Trujano
M
M
D000818:Animals; D000831:Animals, Newborn; D000914:Antibodies, Viral / Q000032:analysis*; D005260:Female; D011558:Herpesvirus 1, Suid / Q000276:immunology*; D007112:Immunity, Maternally-Acquired; D011247:Pregnancy; D011557:Pseudorabies / Q000276:immunology*; D013552:Swine; D013553:Swine Diseases / Q000276:immunology*
D000914:Antibodies, Viral