Fatal intoxication by Remoxipride.
The case history and toxicologic findings of a 23-year-old woman who committed suicide with Remoxipride are described. Remoxipride is a recently developed neuroleptic drug of the benzamide type. Remoxipride was detected in the liver, stomach content, blood, and urine. The concentration of Remoxipride in the blood was 230 mg/L. The recommended therapeutic level for Remoxipride should not exceed 7 to 8 mg/L. The victim had no blood alcohol, but an ethanol concentration of 0.048 g/100 L was detected in the urine. The mechanism of death from Remoxipride intoxication is not known. In clinical studies, sinus bradycardia and infrequent supraventricular and ventricular ectopic beats have been noted.
Segerberg-Konttinen
M
M
Department of Forensic Medicine, University of Helsinki, Finland.
Vuori
E
E
Lukkari
I
I
Penttilä
A
A
D000328:Adult; D001549:Benzamides / Q000493:pharmacokinetics / Q000506:poisoning*; D005260:Female; D006801:Humans; D017330:Remoxipride; D013405:Suicide / Q000331:legislation & jurisprudence*; D014018:Tissue Distribution
D001549:Benzamides; D017330:Remoxipride