Experimental demonstration in the rat of the role played by human alpha 1 glycoprotein (HAAG) in the nonlinearity of RU 486 pharmacokinetics in women.
Tremblay
D
D
Centre de Recherche Roussel Uclaf, Romainville, France.
Busigny
M
M
Bonnat
C
C
Pottier
J
J
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004963:Estrenes / Q000097:blood / Q000493:pharmacokinetics*; D005260:Female; D006801:Humans; D008657:Metabolic Clearance Rate; D015735:Mifepristone; D008954:Models, Biological; D009961:Orosomucoid / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013047:Specific Pathogen-Free Organisms
D004963:Estrenes; D009961:Orosomucoid; D015735:Mifepristone