title: [Respective contributions of atomic emission spectrometry (AES) and secondary ion mass spectrometry (SIMS) to trace element quantification].
abstract: By means of Secondary Ion Mass Spectrometry (SIMS) it is possible to measure in situ the relative concentration of a given element in a volume of 1 micron 3. Atomic Emission Spectrometry (AES) allows absolute quantitation of tissue homogenates. The use of both techniques lead to correlate relative and absolute elemental concentrations. These methods have been applied to lithium and manganese quantitation after treatments at a therapeutic dose. The results assess the sensibility of SIMS analysis, around 0.1 ppm in biological specimens, and confirm the adequacy of the instrument to trace elements study.
authors.affiliation: Groupe d'Etude des Eléments Traces, Université Paris Sud, Orsay, France.
authors.forename: J
authors.initials: J
authors.lastname: Aïoun
authors.forename: E
authors.initials: E
authors.lastname: Larras-Regard
authors.forename: M C
authors.initials: MC
authors.lastname: Mony
authors.forename: M F
authors.initials: MF
authors.lastname: Hutin
authors.forename: D
authors.initials: D
authors.lastname: Burnel
mesh_terms: D000818:Animals; D005260:Female; D007668:Kidney / Q000032:analysis; D008094:Lithium / Q000032:analysis* / Q000097:blood; D008345:Manganese / Q000032:analysis* / Q000097:blood; D013058:Mass Spectrometry / Q000379:methods*; D051379:Mice; D008815:Mice, Inbred Strains; D009206:Myocardium / Q000032:analysis; D013054:Spectrophotometry, Atomic / Q000379:methods*; D013961:Thyroid Gland / Q000032:analysis; D014131:Trace Elements / Q000032:analysis / Q000097:blood
chemical_list: D014131:Trace Elements; D008345:Manganese; D008094:Lithium
vernacular_title: Apports respectifs de la spectrométrie d'émission atomique (SEA) et de la spectrométrie de masse des ions secondaires (SIMS) à la quantification des éléments traces.