Hyperkeratosis palmoplantaris with premature periodontal destruction (Papillon Lefevre syndrome)--report of two cases.
Hyperkeratosis palmoplantaris or Papillon-Lefevre Syndrome (PLS) is a rare condition believed to be inherited as an autosomal recessive trait. The disease is characterized by hyperkeratosis of the palms and soles, with a concomitant severe periodontal destruction. This association between the skin and the oral lesions, offers greater possibility of differentiating the disease from other forms of palmoplantar hyperkeratosis or periodontal disease. In this report, hyperkeratosis palmoplantaris affecting two Sudanese children is discussed.
Ghandour
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D000293:Adolescent; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000473:pathology*; D008297:Male; D010214:Papillon-Lefevre Disease / Q000175:diagnosis / Q000235:genetics / Q000473:pathology*; D013397:Sudan