title: Allergic contact sensitivity to quinophthalone.
abstract: A 73-year-old patient, diagnosed as having seborrheic dermatitis, was patch tested with his hair preparations. The hair stick gave a positive reaction. Among its ingredients, D & C Yellow No. 11, from 0.0001% to 0.1%, and perfume showed positive reactions. D & C Yellow No. 11 was found to consist only of quinophthalone by chemical analyses. The concentration of quinophthalone in the hair stick was determined as 9.41 ppm w/w by high-performance liquid chromatography.
authors.affiliation: Department of Dermatology, Osaka University School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Komamura
authors.forename: T
authors.initials: T
authors.lastname: Kozuka
authors.forename: M
authors.initials: M
authors.lastname: Ishii
authors.forename: K
authors.initials: K
authors.lastname: Yoshikawa
authors.forename: M
authors.initials: M
authors.lastname: Iyoda
mesh_terms: D000368:Aged; D002851:Chromatography, High Pressure Liquid; D003877:Dermatitis, Contact / Q000175:diagnosis / Q000209:etiology*; D012628:Dermatitis, Seborrheic / Q000175:diagnosis; D003951:Diagnostic Errors; D006203:Hair Preparations / Q000009:adverse effects* / Q000032:analysis; D006801:Humans; D007192:Indenes / Q000009:adverse effects*; D008297:Male; D010328:Patch Tests; D011804:Quinolines / Q000009:adverse effects*; D012536:Scalp Dermatoses / Q000175:diagnosis / Q000209:etiology*
chemical_list: D006203:Hair Preparations; D007192:Indenes; D011804:Quinolines; C059790:quinophthalone