Interleukin 1, tumor necrosis factor, and interleukin 6 as mediators of cartilage destruction.
Shinmei
M
M
Department of Orthopedic Surgery, National Defense Medical College, Saitama, Japan.
Masuda
K
K
Kikuchi
T
T
Shimomura
Y
Y
D000911:Antibodies, Monoclonal; D002358:Cartilage, Articular / Q000378:metabolism*; D002478:Cells, Cultured; D006801:Humans; D007150:Immunohistochemistry; D007375:Interleukin-1 / Q000494:pharmacology*; D015850:Interleukin-6; D007378:Interleukins / Q000096:biosynthesis / Q000494:pharmacology*; D008666:Metalloendopeptidases; D003012:Microbial Collagenase / Q000096:biosynthesis / Q000378:metabolism; D010447:Peptide Hydrolases / Q000096:biosynthesis / Q000378:metabolism; D011509:Proteoglycans / Q000378:metabolism; D011994:Recombinant Proteins; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology*
D000911:Antibodies, Monoclonal; D007375:Interleukin-1; D015850:Interleukin-6; D007378:Interleukins; D011509:Proteoglycans; D011994:Recombinant Proteins; D014409:Tumor Necrosis Factor-alpha; D010447:Peptide Hydrolases; D008666:Metalloendopeptidases; C030895:caseinase; D003012:Microbial Collagenase