title: Comparison between intra- and extracellular surfactant in respiratory distress induced by oleic acid.
abstract: The present study compares the phospholipid distribution and protein content in bronchoalveolar lavage, purified extracellular surfactant and lamellar bodies isolated from rabbits killed at intervals of 2.5, 12 and 24 h after oleic acid administration. The data suggest that the alteration of pulmonary surfactant could be partially due to the type II cell response to the injury.
authors.affiliation: Department of Biochemistry, Faculty of Chemistry, Universidad Complutense, Madrid, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Casals
authors.forename: L
authors.initials: L
authors.lastname: Herrera
authors.forename: E
authors.initials: E
authors.lastname: Miguel
authors.forename: P
authors.initials: P
authors.lastname: Garcia-Barreno
authors.forename: A M
authors.initials: AM
authors.lastname: Municio
mesh_terms: D000818:Animals; D001992:Bronchoalveolar Lavage Fluid / Q000032:analysis; D002479:Inclusion Bodies / Q000378:metabolism; D008244:Lysophosphatidylcholines / Q000378:metabolism; D008297:Male; D019301:Oleic Acid; D009829:Oleic Acids; D010743:Phospholipids / Q000378:metabolism; D011663:Pulmonary Surfactants / Q000378:metabolism*; D011817:Rabbits; D012128:Respiratory Distress Syndrome / Q000139:chemically induced / Q000378:metabolism*; D013109:Sphingomyelins / Q000378:metabolism
chemical_list: D008244:Lysophosphatidylcholines; D009829:Oleic Acids; D010743:Phospholipids; D011663:Pulmonary Surfactants; D013109:Sphingomyelins; D019301:Oleic Acid