[Clinico-therapeutic experience with a new antihypertensive drug, ketanserin, in elderly patients].
After a placebo run-in period (one week) 32 hypertensive patients suffering also from other disorders (cardiovascular pathology, diabetes, psychic or neurotic pathology) were treated with ketanserin (20 mg twice daily p.o. for 15 days followed by 40 mg twice daily for another 65 days). The patients' (13 men, 10 women) ages ranged from 54-94 years (average 69 years). Therapeutic results became manifest gradually with significant reductions of systolic and diastolic blood pressure; heart rate, too, had decreased slightly at the end of the treatment period. Global evaluation yielded favorable results in 59% of patients. Topical and systemic tolerance was satisfactory.
Neri
G
G
Iovine
C
C
D000368:Aged; D000369:Aged, 80 and over; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007650:Ketanserin / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged
D007650:Ketanserin
Esperienza clinico-terapeutica con un nuovo farmaco antiipertensivo, la ketanserina, in pazienti anziani.