title: Atrial natriuretic peptides and tubular sodium handling during normal daily life in men.
abstract: The relationship between segmental renal tubular sodium handling (using the renal clearance of ingested lithium as a marker of proximal tubular sodium handling) and circulating plasma levels of atrial natriuretic factor (ANF) was studied in a sample of 295 untreated men drawn from a male population at work under their usual living conditions. Plasma ANF was positively and significantly related to sodium excretion at the distal nephron, indicating that this hormone interacts with a distal renal tubular site to influence the control of sodium excretion in man.
authors.affiliation: Department of Internal Medicine and Metabolic Diseases, 2nd Medical School, University of Naples, Italy.
authors.forename: F P
authors.initials: FP
authors.lastname: Cappuccio
authors.forename: P
authors.initials: P
authors.lastname: Strazzullo
authors.forename: G
authors.initials: G
authors.lastname: Barba
authors.forename: R
authors.initials: R
authors.lastname: Iacone
authors.forename: M G
authors.initials: MG
authors.lastname: Buckley
authors.forename: A L
authors.initials: AL
authors.lastname: Sugden
authors.forename: M
authors.initials: M
authors.lastname: Miller
authors.forename: G A
authors.initials: GA
authors.lastname: Sagnella
authors.forename: G A
authors.initials: GA
authors.lastname: MacGregor
authors.forename: M
authors.initials: M
authors.lastname: Mancini
mesh_terms: D000328:Adult; D000450:Aldosterone / Q000097:blood; D009320:Atrial Natriuretic Factor / Q000097:blood*; D003404:Creatinine / Q000652:urine; D006801:Humans; D007684:Kidney Tubules / Q000378:metabolism*; D008094:Lithium / Q000652:urine; D016651:Lithium Carbonate; D008297:Male; D008875:Middle Aged; D009318:Natriuresis / Q000502:physiology; D012016:Reference Values; D012083:Renin / Q000097:blood; D012964:Sodium / Q000378:metabolism*
chemical_list: D016651:Lithium Carbonate; D000450:Aldosterone; D009320:Atrial Natriuretic Factor; D008094:Lithium; D012964:Sodium; D003404:Creatinine; D012083:Renin