[Action of estradiol-17 beta, estrone sulfate and progesterone on the growth and differentiation of endometrial epithelial cells of the guinea pig in primary culture].
Endometrial guinea-pig glandular epithelial cells grown in primary culture incorporated [3H] thymidine. After three washings with a steroid-free medium, they were made quiescent and arrested in the G0/G1 phase. However, they remained hormone-responsive and resumed the cellular cycle after stimulation by 10(-6) M oestrone sulphate but not by oestradiol-17 beta.
Alkhalaf
M
M
INSERM U 198, Biochimie Hormonale et des Régulations, Besançon.
Propper
A
A
Adessi
G L
GL
D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D004247:DNA / Q000096:biosynthesis; D004717:Endometrium / Q000166:cytology* / Q000187:drug effects; D004847:Epithelial Cells; D004958:Estradiol / Q000494:pharmacology*; D004970:Estrone / Q000031:analogs & derivatives* / Q000494:pharmacology; D005260:Female; D006168:Guinea Pigs; D011374:Progesterone / Q000494:pharmacology*; D015238:Sulfotransferases; D013466:Sulfurtransferases / Q000378:metabolism; D013629:Tamoxifen / Q000494:pharmacology / Q000031:analogs & derivatives
D013629:Tamoxifen; C016601:afimoxifene; D004970:Estrone; D011374:Progesterone; D004958:Estradiol; D004247:DNA; D013466:Sulfurtransferases; D015238:Sulfotransferases; C020122:estrone sulfotransferase; C017296:estrone sulfate
Action de l'oestradiol-17 beta, du sulfate d'oestrone et de la progestérone sur la croissance et la différenciation des cellules épithéliales d'endomètre de cobaye en culture primaire.