title: Contact allergy to corticosteroids: a frequently missed diagnosis?
abstract: Contact allergy to corticosteroids is more prevalent than previously recognized and often goes undetected. Nineteen patients with corticosteroid contact allergy are presented. Sixteen reacted to tixocortol pivalate and also to other corticosteroids, particularly to hydrocortisone, which could explain exacerbations of eczema in these cases. Tixocortol pivalate may be a useful marker for screening patients for contact sensitivity to several corticosteroids.
authors.affiliation: Department of Medical Research, University Hospital, Katholieke Universiteit Leuven.
authors.forename: A E
authors.initials: AE
authors.lastname: Dooms-Goossens
authors.forename: H J
authors.initials: HJ
authors.lastname: Degreef
authors.forename: K J
authors.initials: KJ
authors.lastname: Mariën
authors.forename: S A
authors.initials: SA
authors.lastname: Coopman
mesh_terms: D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents; D003875:Drug Eruptions / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000031:analogs & derivatives*; D008297:Male; D008875:Middle Aged; D010328:Patch Tests
chemical_list: D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; C019112:tixocortol pivalate; D006854:Hydrocortisone