[Pulmonary tuberculosis in patients with hereditary glucose-6-phosphate dehydrogenase deficiency].
A study was made of the occurrence of glucose-6-phosphate dehydrogenase (G-6-PDH) deficiency among patients with lung tuberculosis including those suffering from mental diseases (alcoholism or schizophrenia). In Azerbaijani patients, the rate of G-6-PDH demonstration was higher as compared to that among the healthy population. On combined lung tuberculosis and alcoholism the rate of that abnormality demonstration increased whereas on associated lung tuberculosis and schizophrenia, it slightly decreased. Among patients with hereditary G-6-PDH deficiency, the portion of chronic destructive forms of pulmonary tuberculosis is high, the tuberculous process is accompanied more often by isolation of M. tuberculosis. The etiological role of G-6-PDH as a genetic marker is evaluated as 14%; in associated lung tuberculosis and alcoholism, it grows to 18%.
Insanov
A B
AB
Abdullaev
F M
FM
Ragimov
A A
AA
Talybova
A M
AM
Umniashkin
A A
AA
D001136:Armenia / Q000208:ethnology; D001382:Azerbaijan; D004198:Disease Susceptibility / Q000453:epidemiology / Q000208:ethnology; D020022:Genetic Predisposition to Disease; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000453:epidemiology* / Q000208:ethnology / Q000235:genetics; D006801:Humans; D015995:Prevalence; D012307:Risk Factors; D012426:Russia / Q000208:ethnology; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology* / Q000208:ethnology
Tuberkulez legkikh u bol'nykh s nasledstvennym defitsitom gliukozo-6-fosfatdegidrogenazy.