[Codominant nature of alleles of locus E2 controlling synthesis of human blood serum cholinesterase].
The C5 component of ChE2 (locus E2) of human serum is not an autosomal dominant trait. This component is a part of the group of isozymes C5-10 which can be detected by polyacrylamide gel electrophoresis in acid medium (pH 4.8). The new electrophoretic data show that polymorphism of ChE2 is determined rather by a pair of autosomal codominant alleles called ChE2A and ChE2B. Serum of subjects with phenotypes ChE2AB (C5+) and ChE2BB (C5-) shows the same level of cholinesterase activity on the average.
Shubin
P N
PN
Efimtseva
E A
EA
D000483:Alleles; D002802:Cholinesterases / Q000096:biosynthesis* / Q000097:blood / Q000235:genetics; D002874:Chromosome Mapping; D005799:Genes, Dominant; D005838:Genotype; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007527:Isoenzymes / Q000096:biosynthesis* / Q000097:blood / Q000235:genetics; D010641:Phenotype; D012426:Russia
D007527:Isoenzymes; D002802:Cholinesterases
Kodominantnaia priroda alleleĭ lokusa E2, kontroliruiushchego sintez kholinésterazy syvorotki krovi cheloveka.