title: Postradiation astrocytoma. Report of two cases.
abstract: The authors describe two cases of malignant astrocytomas associated with previous radiation therapy in childhood for intracranial germinoma and craniopharyngioma. In both patients, there was no recurrence at the primary tumor site. Because of a geometric coincidence between the tumor location and the radiation field, radiotherapy was strongly implicated as a cause of these two astrocytomas.
authors.affiliation: Department of Neurosurgery, University of Tokyo Hospital, Japan.
authors.forename: C
authors.initials: C
authors.lastname: Kitanaka
authors.forename: N
authors.initials: N
authors.lastname: Shitara
authors.forename: T
authors.initials: T
authors.lastname: Nakagomi
authors.forename: H
authors.initials: H
authors.lastname: Nakamura
authors.forename: S
authors.initials: S
authors.lastname: Genka
authors.forename: K
authors.initials: K
authors.lastname: Nakagawa
authors.forename: A
authors.initials: A
authors.lastname: Akanuma
authors.forename: H
authors.initials: H
authors.lastname: Aoyama
authors.forename: K
authors.initials: K
authors.lastname: Takakura
mesh_terms: D000293:Adolescent; D001254:Astrocytoma / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D001932:Brain Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D002648:Child; D003397:Craniopharyngioma / Q000532:radiotherapy; D004407:Dysgerminoma / Q000532:radiotherapy; D005260:Female; D005909:Glioblastoma / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D009381:Neoplasms, Radiation-Induced; D010870:Pineal Gland; D010911:Pituitary Neoplasms / Q000532:radiotherapy