title: [Resection of liver metastasis of colo-rectal cancer].
abstract: Surgical resection currently represents the only available approach to improve the survival rate of patients with liver metastases from carcinoma of colon and rectum. The mean 5-year survival rate in patients treated with liver resection is 25% (with a range from 16 to 45%). Despite the lack of safe criteria for selection of patients with liver metastases, the following factors can give indications to surgical resection: evidence of single or multiple, but unilobar, metastases; lack of hepatic hilum metastases; easy approach; satisfactory liver function after resection; staging and grading of primary tumor, timing between resection of primary tumor and diagnosis of liver metastases; safe margin of liver resection (10 mm) from metastatic lesions. To improve the surgical treatment of liver metastases from colo-rectal cancer, larger series of patients and aggressive surgical approach are needed, with mortality rates acceptable for long-term better results.
authors.forename: B
authors.initials: B
authors.lastname: Nordlinger
authors.forename: J C
authors.initials: JC
authors.lastname: Vaillant
authors.forename: A
authors.initials: A
authors.lastname: Carditello
mesh_terms: D015179:Colorectal Neoplasms / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*; D009364:Neoplasm Recurrence, Local
vernacular_title: La resezione delle metastasi epatiche da cancro del colon-retto.