Mouse brain Tau proteins: microheterogeneity and phosphorylation.
Tau proteins are involved in polymerization of tubulin into microtubules. They comprise a heterogeneous group of proteins that can be resolved by two-dimensional gel electrophoresis using a non-equilibrium pH gradient in the first dimension. Developmental studies show that mouse brain Tau proteins are more heterogeneous in 15-day old mice than in newborn pups or adults. Tau phosphorylation is also more heterogeneous at this stage.
Araujo
H M
HM
Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Brasil.
Keller
R P
RP
Fellous
A
A
Chagas
C
C
Moura-Neto
V
V
D000818:Animals; D001345:Autoradiography; D001921:Brain / Q000378:metabolism*; D015180:Electrophoresis, Gel, Two-Dimensional; D051379:Mice; D008869:Microtubule-Associated Proteins / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism*; D010766:Phosphorylation; D016875:tau Proteins
D008869:Microtubule-Associated Proteins; D016875:tau Proteins