title: Translational energy release and stereochemistry of steroids. 14. Epimeric dihydroxy steroids of the androstane series.
abstract: The stereochemistry of dihydroxy steroids, both the mode of the A/B ring junctions and the configuration of OH groups, may be determined from translational energy (T50%) measurements for the loss of a CH.3 radical, from the ratios of metastable-ion peak heights to those of the main beam (determined for the dehydration reactions), and by comparing unimolecular and collision-induced, mass-analysed ion kinetic energy spectra of the new main beam of [M-H2O]+ ions (i.e. those formed via dehydration of metastable molecular ions of epimeric hydroxy steroids in the first field-free region of a double-focusing mass spectrometer.
authors.affiliation: Isotope Department, Weizmann Institute of Science, Rehovot, Israel.
authors.forename: Z V
authors.initials: ZV
authors.lastname: Zaretskii
authors.forename: D
authors.initials: D
authors.lastname: Ghosh
authors.forename: A G
authors.initials: AG
authors.lastname: Brenton
authors.forename: J H
authors.initials: JH
authors.lastname: Beynon
mesh_terms: D000731:Androstanes / Q000737:chemistry*; D013058:Mass Spectrometry / Q000379:methods; D013237:Stereoisomerism
chemical_list: D000731:Androstanes