Allergic contact sensitivity to quinophthalone.
A 73-year-old patient, diagnosed as having seborrheic dermatitis, was patch tested with his hair preparations. The hair stick gave a positive reaction. Among its ingredients, D & C Yellow No. 11, from 0.0001% to 0.1%, and perfume showed positive reactions. D & C Yellow No. 11 was found to consist only of quinophthalone by chemical analyses. The concentration of quinophthalone in the hair stick was determined as 9.41 ppm w/w by high-performance liquid chromatography.
Komamura
H
H
Department of Dermatology, Osaka University School of Medicine, Japan.
Kozuka
T
T
Ishii
M
M
Yoshikawa
K
K
Iyoda
M
M
D000368:Aged; D002851:Chromatography, High Pressure Liquid; D003877:Dermatitis, Contact / Q000175:diagnosis / Q000209:etiology*; D012628:Dermatitis, Seborrheic / Q000175:diagnosis; D003951:Diagnostic Errors; D006203:Hair Preparations / Q000009:adverse effects* / Q000032:analysis; D006801:Humans; D007192:Indenes / Q000009:adverse effects*; D008297:Male; D010328:Patch Tests; D011804:Quinolines / Q000009:adverse effects*; D012536:Scalp Dermatoses / Q000175:diagnosis / Q000209:etiology*
D006203:Hair Preparations; D007192:Indenes; D011804:Quinolines; C059790:quinophthalone