title: [Gd-DTPA in the MR diagnosis of pituitary adenomas].
abstract: 25 patients with surgically (n = 14) and/or biochemically (n = 20) confirmed pituitary adenomas were examined on a 1.5 T superconducting MR system by means of multislice spin-echo technique, 3 mm thick sections and a 256 x 256 matrix. T1-weighted sagittal and coronal sections were obtained before and after administration of Gd-DTPA (0.1 mmol./kg. BW). 13 microadenomas and 12 macroadenomas were found. In unenhanced T1-weighted images 48% of the adenomas were isointense, 48% were hypointense and 4% were hyperintense. 58% of the adenomas enhanced to a lesser degree, 15% enhanced to a higher degree than the normal pituitary gland. 12% showed equal enhancement and 15% showed hypointense and hyperintense areas simultaneously. In 3 patients (12%) there was evidence of adenoma only in the enhanced images. The delineation of the adenoma from the cavernous sinus was possible in 95% of the enhanced, but only in 25% of the native scans.
authors.affiliation: Zentrales Institut für Radiodiagnostik, Univ. Wien, Allgemeines Krankenhaus.
authors.forename: E
authors.initials: E
authors.lastname: Steiner
authors.forename: D
authors.initials: D
authors.lastname: Wimberger
authors.forename: H
authors.initials: H
authors.lastname: Imhof
authors.forename: E
authors.initials: E
authors.lastname: Knosp
authors.forename: P
authors.initials: P
authors.lastname: Hajek
mesh_terms: D000236:Adenoma / Q000175:diagnosis*; D000328:Adult; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid; D010911:Pituitary Neoplasms / Q000175:diagnosis*
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA
vernacular_title: Gd-DTPA in der MR-Diagnostik von Hypophysenadenomen.