No evidence of HTLV-1 infection in Japanese multiple sclerosis patients in polymerase chain reaction.
To test possible association of human T cell leukemia virus type 1 (HTLV-1) with multiple sclerosis (MS), polymerase chain reaction was applied to detect HTLV-1 DNA integrated into peripheral blood mononuclear cell DNA. Nine Japanese MS patients all gave a negative result, indicating no HTLV-1 infection in these MS patients.
Watanabe
T
T
Department of Viral Oncology, Cancer Institute, Tokyo.
Iwasaki
Y
Y
Tashiro
K
K
Yoshida
M
M
D004279:DNA, Viral / Q000032:analysis*; D015490:HTLV-I Infections / Q000150:complications / Q000175:diagnosis*; D015368:Human T-lymphotropic virus 1 / Q000235:genetics*; D006801:Humans; D009103:Multiple Sclerosis / Q000382:microbiology*; D016133:Polymerase Chain Reaction
D004279:DNA, Viral