[Activity of the red-cell C3b receptor and the circulating immuno-complex in patients of herpes simplex keratitis].
The activity of red-cell C3b receptor and the level of circulating immuno-complex in 35 cases of herpes simplex stromal keratitis were determined, with the results that during the stage of acute attack, the former was significantly lowered, while the level of the latter became markedly higher than that of the controls, and after treatment, the indicators returned to normal values. There was a negative correlation between the red-cell C3b receptor activity and the circulating immuno-complex in serum, indicating that the immuno-function of red-cells in patients with herpes simplex stromal keratitis was impaired and the depression of red-cell C3b receptor activity was one of the reasons for the elevated concentration of circulating immuno-complex in serum.
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D000293:Adolescent; D000328:Adult; D000936:Antigen-Antibody Complex / Q000378:metabolism*; D003179:Complement C3b / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D006801:Humans; D007635:Keratitis, Dendritic / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D011951:Receptors, Complement / Q000276:immunology*; D017463:Receptors, Complement 3b
D000936:Antigen-Antibody Complex; D011951:Receptors, Complement; D017463:Receptors, Complement 3b; D003179:Complement C3b