[Spatial identification of an excess of cerebral tumors in a highly industrialized small area: results of a case-control study].
A case-Control Study for the association between Central Nervous System Malignancies and residence in a small area within the municipality of Campi Bisenzio (Florence, Italy) has been performed following a spontaneous reporting of three cases of brain cancer. All incident cases of SNC tumours diagnosed in the period 1973-82 with histological or radiological confirmation among residents in the study area are recruited as cases. Five controls for each case, matched by sex and age (+ - 1 year), are randomly chosen from demographic files in the municipality. The residential history for each subject enrolled in the study is recorded from the same demographic files. The relative risk for ever resident in the 46-50 electoral sections relative to never resident was 7.33 (C.I. 95% 2.6-20.3). A trend for duration of residence was also relevant (less than 5 years RR = 2.1, 5-10 years RR = 8.4, more than 10 years RR = 11.3; chi-square for trend = 41 p = 0.00002).
Biggeri
A
A
Buiatti
E
E
Arfaioli
C
C
Baroni
A
A
Carloni
M
M
Tomassini
A
A
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000453:epidemiology*; D016022:Case-Control Studies; D002648:Child; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D007221:Industry; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D014504:Urban Health
Identificazione spaziale di un eccesso di tumori cerebrali in una piccola area fortemente industrializzata: risultati di uno studio caso-controllo.