Metabolic pathway of paroxetine in animals and man and the comparative pharmacological properties of its metabolites.
Haddock
R E
RE
Beecham Pharmaceuticals Research Division, Medicinal Research Centre, Harlow, Essex, United Kingdom.
Johnson
A M
AM
Langley
P F
PF
Nelson
D R
DR
Pope
J A
JA
Thomas
D R
DR
Woods
F R
FR
D000818:Animals; D000928:Antidepressive Agents / Q000493:pharmacokinetics* / Q000494:pharmacology; D001711:Biotransformation; D001921:Brain / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D006801:Humans; D007031:Hypothalamus / Q000187:drug effects; D051379:Mice; D017374:Paroxetine; D010880:Piperidines / Q000493:pharmacokinetics*; D051381:Rats; D011985:Receptors, Serotonin / Q000187:drug effects; D012702:Serotonin Antagonists / Q000493:pharmacokinetics* / Q000494:pharmacology; D013329:Structure-Activity Relationship; D013574:Synaptosomes / Q000187:drug effects
D000928:Antidepressive Agents; D010880:Piperidines; D011985:Receptors, Serotonin; D012702:Serotonin Antagonists; D017374:Paroxetine