title: [The ploidy variability of human cardiomyocytes].
abstract: Unlike literature on ploidy of the human myocytes, DNA content and the number of nuclei have been revealed in the same cells. Besides, the cell ploidy were studied separately in the external, central and inner regions in the left ventricule. Considerable binucleation was revealed in normal and hypertrophic ventricles where 4c X2 was the modal cell class and there were 2c X 2, 8c X 2 and single 16c X 2 cells. Two alternative assumptions have been put forward concerning the genome differences: 1) myocytes enter in mitotic cycle under pathologic conditions or 2) the difference causes in genuine variability of the ploidy classes in normal hearts.
authors.forename: V Ia
authors.initials: VIa
authors.lastname: Brodskiĭ
authors.forename: I A
authors.initials: IA
authors.lastname: Vasil'eva
authors.forename: N V
authors.initials: NV
authors.lastname: Panova
authors.forename: D S
authors.initials: DS
authors.lastname: Sarkisov
authors.forename: A M
authors.initials: AM
authors.lastname: Aref'eva
mesh_terms: D000293:Adolescent; D000328:Adult; D006332:Cardiomegaly / Q000473:pathology; D004247:DNA / Q000648:ultrastructure; D014644:Genetic Variation; D006801:Humans; D008875:Middle Aged; D009206:Myocardium / Q000648:ultrastructure*; D011003:Ploidies
chemical_list: D004247:DNA
vernacular_title: Variabel'nost' ploidnosti kardiomiotsitov cheloveka.