[Adenosine deaminase activity in peritoneal tuberculosis].
We performed a prospective study including cytochemical, bacteriologic and pathologic observations in 25 patients with ascites of different causes. Activity of adenosine deaminase in ascitic fluid was higher in tuberculous (103 +/- 61 mu/l) than in neoplastic (16 +/- 8), inflammatory (16 +/- 13) and portal hypertension (15 +/- 6) etiologies (p less than 0.05). Inflammatory cases included patients with lupus and spontaneous peritonitis. Activity of adenosine deaminase was higher in every patient with tuberculosis than in any other patient. Thus, a high sensitivity and specificity of this test in the diagnosis of tuberculous peritonitis is confirmed.
Sapunar
J
J
Sapunar
J
J
Velásco
C
C
Poniachik
J
J
Paredes
R
R
D000243:Adenosine Deaminase / Q000032:analysis*; D001202:Ascitic Fluid / Q000201:enzymology*; D015415:Biomarkers; D004796:Clinical Enzyme Tests; D006801:Humans; D014395:Peritonitis, Tuberculous / Q000175:diagnosis*
D015415:Biomarkers; D000243:Adenosine Deaminase
Actividad de adenosin deaminasa en tuberculosis peritoneal.