title: Effects of the putative phospholipid precursors, inositol, choline, serine and ethanolamine, on formation and expansion of rabbit blastocysts in vitro.
abstract: Rabbit morulae were cultured to blastocysts in various concentrations of the potential phospholipid precursors, myo-inositol, choline, serine and ethanolamine. Serine (20-2500 microM) had a significant stimulatory effect on blastocyst formation and blastocyst expansion and inositol (3-375 microM) had a significant stimulatory effect on blastocyst expansion. There was no significant stimulatory effect of choline or ethanolamine.
authors.affiliation: Department of Physiology, University College, Galway, Ireland.
authors.forename: M T
authors.initials: MT
authors.lastname: Kane
mesh_terms: D000818:Animals; D001755:Blastocyst / Q000187:drug effects / Q000502:physiology*; D002794:Choline / Q000494:pharmacology; D003470:Culture Media; D046508:Culture Techniques; D004305:Dose-Response Relationship, Drug; D019856:Ethanolamine; D004983:Ethanolamines / Q000494:pharmacology; D005260:Female; D007294:Inositol / Q000494:pharmacology; D010743:Phospholipids / Q000378:metabolism*; D011817:Rabbits; D012694:Serine / Q000494:pharmacology
chemical_list: D003470:Culture Media; D004983:Ethanolamines; D010743:Phospholipids; D012694:Serine; D007294:Inositol; D019856:Ethanolamine; D002794:Choline