title: [LHRH in the human hypothalamus. Immunohistochemical mapping in normal newborn infants or in sudden death infants].
abstract: The topographical distribution of neurons containing LHRH has been investigated in newborn hypothalamus using the peroxidase anti-peroxidase technique. In control subjects, LHRH immunoreactive (LHRH-IR) perikarya have been mainly observed essentially in the infundibular nucleus. The preoptic region displayed a moderate density of LHRH-IR cell bodies. High LHRH innervation was observed in the anterior hypothalamus in the lamina terminalis and in the mediobasal hypothalamus in the median eminence, and in the peri- and paraventricular regions. In sudden death infant syndrome, a comparable mapping was observed, except a low density in the mediobasal peri- and paraventricular areas.
authors.affiliation: Laboratoire d'Anatomie pathologique, Faculté de Médecine Alexis-Carrel, Lyon.
authors.forename: M
authors.initials: M
authors.lastname: Najimi
authors.forename: F
authors.initials: F
authors.lastname: Chigr
authors.forename: D
authors.initials: D
authors.lastname: Jordan
authors.forename: M
authors.initials: M
authors.lastname: Tommasi
authors.forename: P
authors.initials: P
authors.lastname: Rebaud
authors.forename: S
authors.initials: S
authors.lastname: Gallet
authors.forename: N
authors.initials: N
authors.lastname: Kopp
mesh_terms: D001931:Brain Mapping; D007987:Gonadotropin-Releasing Hormone / Q000032:analysis*; D006801:Humans; D007031:Hypothalamus / Q000032:analysis*; D007032:Hypothalamus, Anterior / Q000032:analysis; D007033:Hypothalamus, Middle / Q000032:analysis; D007034:Hypothalamus, Posterior / Q000032:analysis; D007150:Immunohistochemistry; D007223:Infant; D007231:Infant, Newborn; D012016:Reference Values; D013398:Sudden Infant Death
chemical_list: D007987:Gonadotropin-Releasing Hormone
vernacular_title: LHRH dans l'hypothalamus humain. Etude cartographique immunohistochimique chez des nourrissons témoins ou décédés de "mort subite inexpliquée".