A multi-centre randomised study to compare the effects of ovarian ablation with Zoladex depot in pre- and perimenopausal patients with advanced breast cancer.
The aim of a trial that will determine and compare the efficacy and safety of ovarian ablation (either surgical oophorectomy or irradiation) with depot Zoladex in the treatment of pre- and perimenopausal patients with advanced breast cancer is discussed.
Tyrrell
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Department of Radiotherapy and Oncology, Freedom Fields, Plymouth General Hospital, UK.
D001943:Breast Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D002064:Buserelin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003692:Delayed-Action Preparations; D005260:Female; D017273:Goserelin; D006801:Humans; D015337:Multicenter Studies as Topic; D010052:Ovariectomy; D016032:Randomized Controlled Trials as Topic
D003692:Delayed-Action Preparations; D017273:Goserelin; D002064:Buserelin