[Significance of leukocyte scintigraphy of the infected total endoprosthesis].
31 patients with suspected septic loosening of an endoprosthesis (hip endoprosthesis n = 30; knee endoprosthesis n = 1) were examined with leukocyte scans (10 MBq 111In-oxine: n = 22; 300 MBq 99mTc-HMPAO: n = 9). The results were compared with results of the bacterial growth (n = 22), the histology (n = 12) and of the bone scans (99mTc-MDP: n = 20) which were performed within 4 days. The sensitivity of the bone scan was 100%, the specificity 30% and the diagnostic accuracy regarding a septic loosening of the arthroplasty was 55%. For the leukocyte scans a comparable sensitivity of 100%, but a higher specificity (86%) and accuracy (91%) could be calculated. A false positive leukocyte scan could be observed in a periprosthetic granuloma, an ossifying periarthritis and in a patient with negative bacterial growth with the histological proof of an inflammation.
Becker
W
W
Klinik und Poliklinik für Nuklearmedizin, Universität Würzburg.
Pasurka
B
B
Börner
W
W
D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000000981:diagnostic imaging*; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D007205:Indium Radioisotopes; D007720:Knee Prosthesis; D007962:Leukocytes; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D010091:Oximes; D015125:Oxyquinoline / Q000031:analogs & derivatives; D011475:Prosthesis Failure; D011877:Radionuclide Imaging; D013667:Technetium; D019690:Technetium Tc 99m Exametazime
D007205:Indium Radioisotopes; D009942:Organometallic Compounds; D010091:Oximes; C032950:indium oxine; D019690:Technetium Tc 99m Exametazime; D015125:Oxyquinoline; D013667:Technetium
Bedeutung der Leukozytenszintigraphie bei der infizierten Totalendoprothese.