Epidemiologic and clinical aspects of feline immunodeficiency virus infection in cats from the continental United States and Canada and possible mode of transmission.
The epidemiologic features of feline immunodeficiency virus (FIV) infection were evaluated in 2,765 cats from the United States and Canada. Of these cats, 2,254 were considered by veterinarians to be at high risk for the infection, and 511 were healthy cats considered to be at low or unknown risk. Of the cats in the high-risk group, 318 (14%) were found to be infected with FIV. The infection rate among low- or unknown-risk cats was 6 of 511 (1.2%). Male cats in the high-risk group were 3 times more likely to be infected than were females, similarly as were cats greater than 6 years old, compared with younger cats; domestic cats, compared with purebred cats; and free-roaming cats, compared with confined cats. Feline immunodeficiency virus and FeLV infections did not appear to be linked with each other; 16% of FeLV-infected cats in the high- and low-risk groups were coinfected with FIV. In contrast, there was a pronounced linkage between FIV and feline syncytium-forming virus (FeSFV) infections. Seventy-four percent of FeSFV-infected cats in the high-risk study group were coinfected with FIV, compared with a 38% FIV infection rate among cats that were not infected with FeSFV. The major clinical manifestations associated with FIV infection in cats that were surveyed included chronic oral cavity infections (56%), chronic upper respiratory tract disease (34%), chronic enteritis (19%), and chronic conjunctivitis (11%). Bacterial infections of the urinary tract (cystitis), skin, and ears were seen in a small proportion of cats.(ABSTRACT TRUNCATED AT 250 WORDS)
Yamamoto
J K
JK
Department of Medicine, School of Veterinary Medicine, University of California, Davis 95616.
Hansen
H
H
Ho
E W
EW
Morishita
T Y
TY
Okuda
T
T
Sawa
T R
TR
Nakamura
R M
RM
Pedersen
N C
NC
D000367:Age Factors; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D001733:Bites and Stings / Q000150:complications / Q000662:veterinary; D002170:Canada; D002371:Cat Diseases / Q000453:epidemiology* / Q000209:etiology / Q000635:transmission; D002415:Cats; D005260:Female; D006799:Housing, Animal; D007153:Immunologic Deficiency Syndromes / Q000453:epidemiology / Q000209:etiology / Q000635:transmission / Q000662:veterinary*; D008214:Lymphocytes / Q000382:microbiology; D008297:Male; D009059:Mouth Diseases / Q000209:etiology / Q000662:veterinary; D012190:Retroviridae / Q000276:immunology / Q000302:isolation & purification; D012192:Retroviridae Infections / Q000453:epidemiology / Q000209:etiology / Q000635:transmission / Q000662:veterinary*; D012307:Risk Factors; D012463:Saliva / Q000382:microbiology; D014481:United States
D000914:Antibodies, Viral