title: [Nontraditional fractionation of doses of ionizing radiation in clinical practice].
abstract: Various types of non-routine dose fractionation were used in 2062 patients with malignant tumors of different sites. The conclusion was that superfractionation was more preferable for tumors with a high proliferative pool, with fast growth rates, marked radiosensitivity. It ensures the protection of normal tissues without a decrease or even with an increase in an antitumor effect. Such fractionation can be recommended when large tissue areas are to be irradiated. Dynamic dose fractionation regimens proved to be more effective than the use of large fractions not only in squamous cell carcinoma but also in sarcoma both before operation and as therapy after a radical program.
authors.forename: E S
authors.initials: ES
authors.lastname: Kiseleva
authors.forename: S L
authors.initials: SL
authors.lastname: Dar'ialova
authors.forename: A V
authors.initials: AV
authors.lastname: Boĭko
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Rakhmanin
authors.forename: P Iu
authors.initials: PIu
authors.lastname: Poliakov
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000532:radiotherapy; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000532:radiotherapy; D005770:Gastrointestinal Neoplasms / Q000532:radiotherapy; D006801:Humans; D008175:Lung Neoplasms / Q000532:radiotherapy; D009369:Neoplasms / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D012189:Retrospective Studies; D012983:Soft Tissue Neoplasms / Q000532:radiotherapy
vernacular_title: Netraditsionnoe fraktsionirovanie dozy ioniziruiushchego izlucheniia vklinicheskoĭ praktike.