Enhanced thrombolysis in plasma and in vivo by single-chain urokinase-type plasminogen activator (scuPA) conjugated to an antifibrin antibody.
Bode
C
C
Medizinische Klinik III, Universitat Heidelberg, Germany.
Runge
M
M
Eberle
T
T
Freitag
M
M
Kübler
W
W
Haber
E
E
D000818:Animals; D005337:Fibrin / Q000276:immunology; D005342:Fibrinolysis / Q000187:drug effects*; D005343:Fibrinolytic Agents; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000008:administration & dosage; D066298:In Vitro Techniques; D010960:Plasminogen Activators / Q000008:administration & dosage / Q000494:pharmacology*; D011817:Rabbits; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage / Q000494:pharmacology*
D005343:Fibrinolytic Agents; D007140:Immunoglobulin Fab Fragments; D005337:Fibrin; D010960:Plasminogen Activators; D014568:Urokinase-Type Plasminogen Activator