title: Surgical treatment of prosthetic valve endocarditis with homograft aortic valve replacement.
abstract: This article presents the University of Alabama experience with homograft aortic valve replacement for prosthetic valve endocarditis. Of 117 patients who have undergone homograft aortic valve replacement since 1981, there has been a total of 22 patients who underwent operation for endocarditis. Sixteen were isolated valve replacements, three combined with other procedures, and three were aortic root replacements. When placed in a setting of active endocarditis, there have been no reoperations for endocarditis of the homograft valve. Surgical techniques are presented for the freehand sewn homograft as well as aortic root replacement. Prosthetic valve endocarditis is a highly lethal event and when aortic valve replacement is advised in this setting, we believe a homograft aortic valve should be implanted whenever possible.
authors.affiliation: Department of Surgery, University of Alabama, Birmingham 35294.
authors.forename: J K
authors.initials: JK
authors.lastname: Kirklin
authors.forename: A D
authors.initials: AD
authors.lastname: Pacifico
authors.forename: J W
authors.initials: JW
authors.lastname: Kirklin
mesh_terms: D001021:Aortic Valve / Q000637:transplantation*; D001705:Bioprosthesis; D004697:Endocarditis, Bacterial / Q000401:mortality / Q000601:surgery*; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D017052:Hospital Mortality; D006801:Humans; D016459:Prosthesis-Related Infections / Q000401:mortality / Q000601:surgery*; D012086:Reoperation; D012307:Risk Factors; D013997:Time Factors