[Gastric acid secretion and cellular immunity in patients with gastric cancer].
Three hundred and one gastric cancer patients have been examined preoperatively to investigate their gastric acid secretions after stimulation by tetragastrin, and serum gastrin stimulation by a test meal, as well as for skin reactions and an evaluation of their serum glycoproteins. The results have indicated that their gastric secretions and serum gastrin response were found to be reduced, according to the advancement of their cancer, and that the gastric acid secretion of patients with signet ring cell carcinoma was higher than that of patients with other histological carcinomas. Gastric acid secretions of patients with an ulcerated type of cancer, that is, type IIc and type III in an early cancer stage and type IIc of an advanced Borrmann V type, was higher than in patients with other types, and there were significant correlationships between gastric secretions and PHA skin test and gastric secretions and the IAP and the sialic acid.
Ogoshi
K
K
2nd Dept. of Surgery, School of Med., Tokai Univ.
Iwata
K
K
Hara
S
S
Kondo
Y
Y
Hanaue
H
H
Mitomi
T
T
Harasawa
S
S
Tani
N
N
D002288:Adenocarcinoma, Mucinous / Q000097:blood / Q000276:immunology / Q000378:metabolism; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005744:Gastric Acid / Q000378:metabolism*; D005755:Gastrins / Q000097:blood; D006023:Glycoproteins / Q000097:blood; D006801:Humans; D007111:Immunity, Cellular; D008297:Male; D008875:Middle Aged; D012882:Skin Tests; D013274:Stomach Neoplasms / Q000097:blood / Q000276:immunology / Q000378:metabolism*
D005755:Gastrins; D006023:Glycoproteins