The effect of cholinesterase inhibitors of SFEMG in myasthenia gravis.
We report four patients with myasthenia gravis (MG) in whom single-fiber electromyography (SFEMG) jitter measurements were normal in some muslces while they were taking pyridostigmine and became abnormal 2-14 days after the medication was discontinued. When the abnormality of neuromuscular transmission in MG is mild, cholinesterase inhibitors may mask the findings of increased jitter on SFEMG.
Massey
J M
JM
Duke University Medical Center, Durham, NC 27710.
Sanders
D B
DB
Howard
J F
JF
D000200:Action Potentials; D000293:Adolescent; D000328:Adult; D002800:Cholinesterase Inhibitors / Q000494:pharmacology*; D004576:Electromyography; D005260:Female; D006801:Humans; D009157:Myasthenia Gravis / Q000503:physiopathology*; D009435:Synaptic Transmission / Q000187:drug effects
D002800:Cholinesterase Inhibitors