title: The major kidney band 3 gene transcript predicts an amino-terminal truncated band 3 polypeptide.
abstract: We have characterized multiple transcripts from the band 3 gene expressed in rat and mouse kidney. In each species, the major transcript lacks sequence from the first three exons of the band 3 gene. The murine transcript predicts a kidney band 3 polypeptide with a truncated amino terminus, lacking the first 79 amino acids of erythroid band 3. When expressed in Xenopus oocytes this truncated band 3 functions in anion transport.
authors.affiliation: Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142.
authors.forename: F C
authors.initials: FC
authors.lastname: Brosius
authors.forename: S L
authors.initials: SL
authors.lastname: Alper
authors.forename: A M
authors.initials: AM
authors.lastname: Garcia
authors.forename: H F
authors.initials: HF
authors.lastname: Lodish
mesh_terms: D000818:Animals; D001457:Anion Exchange Protein 1, Erythrocyte / Q000235:genetics*; D001483:Base Sequence; D015342:DNA Probes; D004262:DNA Restriction Enzymes; D004720:Endonucleases; D004912:Erythrocytes / Q000032:analysis; D005091:Exons; D005260:Female; D007438:Introns; D007668:Kidney / Q000032:analysis*; D008297:Male; D051379:Mice; D009693:Nucleic Acid Hybridization; D009865:Oocytes / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics; D051381:Rats; D011919:Rats, Inbred Strains; D015719:Single-Strand Specific DNA and RNA Endonucleases; D014158:Transcription, Genetic; D014982:Xenopus laevis
chemical_list: D001457:Anion Exchange Protein 1, Erythrocyte; D015342:DNA Probes; D012333:RNA, Messenger; D004720:Endonucleases; D004262:DNA Restriction Enzymes; D015719:Single-Strand Specific DNA and RNA Endonucleases