Gastric xanthelasma.
Gastric xanthelasmas are macroscopically well demarcated yellow or yellow-white plaques, and microscopically composed of typical foamy macrophages. Of 3870 patients who underwent upper gastrointestinal panendoscopic examinations, 30 (0.8%) were found to have gastric xanthelasma. A moderate predominance of males over females (M:F = 3.3:1) was noted. The age ranged between 21 and 69 years (mean 46.7). Frequency peaked in those from 40 to 60 years of age (53.3%). Single lesions were found in 26 patients and multiple in 4, with diameters of 1-6 mm, nearly 66.7% of which were 2-3 mm. Gastric xanthelasmas are most frequently found in the antrum (67.8%), especially along the lesser curvature. Associated chronic gastritis in the xanthelasma surrounding mucosa was found in the 30 patients and intestinal metaplasia in 4 (13.3%). The cause of gastric xanthelasma is unknown, but chronic gastritis may be the most plausible etiologic factor.
Chen
Y S
YS
Lin
J B
JB
Dai
K S
KS
Deng
B X
BX
Xu
L Z
LZ
Lin
C D
CD
Jiang
Z G
ZG
D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D013272:Stomach Diseases / Q000453:epidemiology / Q000473:pathology*; D014973:Xanthomatosis / Q000453:epidemiology / Q000473:pathology*