Glomerular filtration barrier in experimental endotoxin shock: a histopathological and physiopathological study.
In the present work a morphopathological study is carried out of the glomerular filtration barrier in 20 Large-White pigs weighing 20 kg, subjected to experimental intravenous inoculations of endotoxin from Salmonella enteritidis. The study is completed with the determination of protein plasmatic levels, through urine test with the determination of pH, density, proteins, glucose, ketone body levels and urinary sediment. The histopathological and physiopathological results reveal alterations at the level of the filtration barrier with quantitative differences between the different experimental groups.
Redondo
E
E
Department of Animal Health and Medicine, Faculty of Veterinary, Cáceres, Spain.
Roncero
V
V
Durán
E
E
Gázquez
A
A
D000818:Animals; D001485:Basement Membrane / Q000648:ultrastructure; D001798:Blood Proteins / Q000378:metabolism; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D004730:Endothelium, Vascular / Q000648:ultrastructure; D007678:Kidney Glomerulus / Q000378:metabolism* / Q000473:pathology / Q000648:ultrastructure; D008854:Microscopy, Electron; D016612:Paraffin Embedding; D012477:Salmonella enteritidis; D012772:Shock, Septic / Q000378:metabolism* / Q000473:pathology / Q000503:physiopathology; D013552:Swine / Q000502:physiology*
D001798:Blood Proteins