title: The influence of PTH, calcium gluconate and EDTA on the parotid saliva in the goat.
abstract: 1. The role of exogenous parathyroid hormone (PTH) and stimulation or inhibition of endogenous hormone release, on the parotid gland of normal and thyroparathyroidectomized (t.x.p.t.x.) goats was studied. 2. The intravenous infusion of PTH and EDTA produced a transitory rise in saliva flow rate in intact animals. In t.x.p.t.x. goats the flow of saliva decreased transiently throughout the infusion. 3. The calcium levels in parotid saliva was unchanged throughout the infusion of PTH, EDTA, calcium gluconate both alone or with propranolol, in either intact or t.x.p.t.x. animals. 4. The parathyroid hormone infusion caused an increase in salivary phosphate concentration in both intact and operated goats. The effects of PTH upon the salivary flow and concentration of P are discussed.
authors.affiliation: Departamento de Fisiología, Facultad de Farmacia, Universidad de Granada, Spain.
authors.forename: M D
authors.initials: MD
authors.lastname: Isac
authors.forename: A
authors.initials: A
authors.lastname: Valverde
authors.forename: M J
authors.initials: MJ
authors.lastname: Lupiani
authors.forename: E
authors.initials: E
authors.lastname: Martinez de Victoria
authors.forename: M
authors.initials: M
authors.lastname: Mañas
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D002118:Calcium / Q000378:metabolism; D002125:Calcium Gluconate / Q000494:pharmacology*; D004492:Edetic Acid / Q000494:pharmacology*; D005942:Gluconates / Q000494:pharmacology*; D006041:Goats; D010280:Parathyroid Glands / Q000601:surgery; D010281:Parathyroid Hormone / Q000494:pharmacology* / Q000502:physiology; D010306:Parotid Gland / Q000378:metabolism*; D010710:Phosphates / Q000378:metabolism; D012463:Saliva / Q000378:metabolism*; D013965:Thyroidectomy
chemical_list: D005942:Gluconates; D010281:Parathyroid Hormone; D010710:Phosphates; D004492:Edetic Acid; D002125:Calcium Gluconate; D002118:Calcium