High phenylacetic acid differentiates schizoaffective from schizophrenic patients.
Twenty-four hour urinary phenylacetic acid was high in 12 acutely psychotic schizoaffective patients (240.3 +/- 51.9 mg/day) and low in 16 acutely psychotic schizophrenic patients (53.6 +/- 15.1 mg/day). These results indicate a biochemical difference between these two types of acute psychoses and indicate alterations in phenylalanine metabolism.
Sabelli
H C
HC
Department of Psychiatry, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois.
Durai
U N
UN
Fawcett
J
J
Javaid
J I
JI
D000328:Adult; D000368:Aged; D002940:Circadian Rhythm; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010648:Phenylacetates / Q000652:urine*; D010649:Phenylalanine / Q000378:metabolism; D011618:Psychotic Disorders / Q000175:diagnosis / Q000378:metabolism / Q000652:urine*; D012559:Schizophrenia / Q000175:diagnosis / Q000378:metabolism / Q000652:urine*
D010648:Phenylacetates; D010649:Phenylalanine