[Neuromuscular effect of atracurium under novocaine-balanced and enflurane-nitrous oxide anesthesia].
The neuromuscular effect of atracurium was compared with the train-of-four stimulation technique during novocaine-balanced and enflurane-nitrous oxide anesthesia in healthy patients undergoing surgery. With equipotent doses (0.5 mg/kg), the duration of neuromuscular effect of atracurium was significantly longer under enflurane-nitrous oxide than that during novocaine-balanced anesthesia (P less than 0.01). This suggests that enflurane-nitrous oxide enhances the blocking effect of atracurium.
Huang
Y G
YG
D000293:Adolescent; D000328:Adult; D000368:Aged; D000769:Anesthesia, Inhalation; D000772:Anesthesia, Local; D001279:Atracurium / Q000494:pharmacology*; D004576:Electromyography; D004737:Enflurane; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009469:Neuromuscular Junction / Q000187:drug effects*; D009609:Nitrous Oxide; D011343:Procaine
D001279:Atracurium; D011343:Procaine; D004737:Enflurane; D009609:Nitrous Oxide