title: Influence of age on the outcome of percutaneous angioplasty in atheromatous renovascular disease.
abstract: We compared the efficacy and safety of percutaneous transluminal renal angioplasty for the treatment of renovascular disease in 66 patients. Thirty-four were aged less than 60 years, and 32 more than 60 years. The younger patients had a shorter known duration of hypertension and higher levels of diastolic pressure (6.4 +/- 9 years and 109 +/- 15 mmHg) than the older patients (12.8 +/- 8 years and 101 +/- 11 mmHg, P less than 0.01 for both comparisons). They also had higher creatinine clearance rates (78 versus 46 ml/min, P less than 0.01) and less severe renal artery disease. A total of 70 percutaneous transluminal renal angioplasties were performed in 70 arteries with a technical success rate of 100% in the younger group versus 67% in the older group (P less than 0.01); complications occurred more frequently in the older group. Our data indicate that, when technically successful, percutaneous transluminal renal angioplasty improves blood pressure to a similar extent in both younger and older patients. However, in patients over 60 years, the safety of the procedure is limited by more severe age-associated atheroma of renal and extrarenal arteries.
authors.affiliation: Service d'Hypertension Artérielle, Hôpital Broussais, Paris, France.
authors.forename: J
authors.initials: J
authors.lastname: Julien
authors.forename: X
authors.initials: X
authors.lastname: Jeunemaitre
authors.forename: A
authors.initials: A
authors.lastname: Raynaud
authors.forename: M
authors.initials: M
authors.lastname: Azizi
authors.forename: J Y
authors.initials: JY
authors.lastname: Pagny
authors.forename: P F
authors.initials: PF
authors.lastname: Plouin
authors.forename: P
authors.initials: P
authors.lastname: Corvol
mesh_terms: D000375:Aging / Q000502:physiology*; D000800:Angioplasty, Balloon; D001161:Arteriosclerosis / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D001794:Blood Pressure / Q000502:physiology; D005500:Follow-Up Studies; D006801:Humans; D006978:Hypertension, Renovascular / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D008875:Middle Aged; D011859:Radiography; D012077:Renal Artery / Q000000981:diagnostic imaging; D013997:Time Factors