Treatment of uterine leiomyomas and hirsutism with nafarelin.
Nafarelin treatment reduces both uterine and myoma volume, induces amenorrhea and improves blood indices in women with uterine leiomyomas. The gonadotropin releasing hormone analog is also effective in decreasing hair growth in women with hirsutism that is associated with excess ovarian androgen production.
Monroe
S E
SE
Department of Reproductive Medicine, Syntex Research, Palo Alto, California.
Andreyko
J
J
D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006628:Hirsutism / Q000188:drug therapy*; D006801:Humans; D007889:Leiomyoma / Q000188:drug therapy*; D017274:Nafarelin; D014594:Uterine Neoplasms / Q000188:drug therapy*
D017274:Nafarelin; D007987:Gonadotropin-Releasing Hormone