The effect of prostacyclin and its analogues on cysteamine-induced duodenal ulceration of rats.
The effect of prostacyclin and its analogues, -6-keto-prostaglandin-F1 alpha and 6-beta-prostaglandin-I1, on cysteamine induced duodenal ulceration of rats has been investigated. It seems that neither prostacyclin nor its analogues have antiulcerogenic effect in this model.
Náfrádi
J
J
First Dept. of Medicine, University Medical School, Szeged, Hungary.
Balint
G A
GA
Varró
V
V
D015121:6-Ketoprostaglandin F1 alpha / Q000627:therapeutic use*; D000818:Animals; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D003543:Cysteamine / Q000633:toxicity; D004381:Duodenal Ulcer / Q000139:chemically induced / Q000188:drug therapy*; D011464:Epoprostenol / Q000627:therapeutic use* / Q000031:analogs & derivatives; D005260:Female; D011465:Prostaglandins, Synthetic / Q000627:therapeutic use*; D051381:Rats; D011919:Rats, Inbred Strains
D000897:Anti-Ulcer Agents; D011465:Prostaglandins, Synthetic; D015121:6-Ketoprostaglandin F1 alpha; D003543:Cysteamine; C022228:5,6-dihydroprostacyclin; D011464:Epoprostenol