title: [Use of immunosuppressed mice in an attempt to improve the diagnosis of infection by Trypanosoma cruzi].
abstract: In order to demonstrate low level parasitemias of Trypanosoma cruzi, a procedure based on the pharmacologic development of immunosuppression and subsequente innoculation of a test blood specimen was evaluated in mice. Prednisone was effective for the procedure and my be considered for diagnosis and for clinical and laboratorial follow-up of patients with Chagas'disease, submitted to heart transplantation. However, prednisone effectiveness depended from the level of parasitemia.
authors.forename: A
authors.initials: A
authors.lastname: Miyamoto
authors.forename: R
authors.initials: R
authors.lastname: Campos
authors.forename: V
authors.initials: V
authors.lastname: Amato Neto
authors.forename: H B
authors.initials: HB
authors.lastname: de Souza
authors.forename: L
authors.initials: L
authors.lastname: Matsubara
authors.forename: A A
authors.initials: AA
authors.lastname: Moreira
mesh_terms: D000818:Animals; D014355:Chagas Disease / Q000276:immunology / Q000401:mortality / Q000469:parasitology*; D007165:Immunosuppression Therapy; D051379:Mice; D008807:Mice, Inbred BALB C; D011241:Prednisone / Q000494:pharmacology*
chemical_list: D011241:Prednisone
vernacular_title: Utilização de camundongos imunodeprimidos como tentativa de aprimoramento do diagnóstico da infecção pelo Trypanosoma cruzi.