Subpopulations of human peripheral T gamma delta lymphocytes.
In the search for the genes encoding the alpha and beta chains of the T-cell receptor, Tonegawa et al. discovered a third class of rearranging T-cell specific genes. This finding led them to postulate the existence of additional forms of T-cell receptors. In this article, Frédéric Tribel and Thierry Hercend briefly discuss recent results, which may help in the delineation of human peripheral blood gamma delta+ subsets based on the molecular structure of this receptor.
Triebel
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F
Hercend
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D000911:Antibodies, Monoclonal; D015329:Gene Rearrangement, T-Lymphocyte; D006801:Humans; D011948:Receptors, Antigen, T-Cell / Q000235:genetics; D016692:Receptors, Antigen, T-Cell, gamma-delta; D013601:T-Lymphocytes / Q000145:classification* / Q000276:immunology
D000911:Antibodies, Monoclonal; D011948:Receptors, Antigen, T-Cell; D016692:Receptors, Antigen, T-Cell, gamma-delta