[Electric left ventricular hypertrophy and pulsatile component of arterial pressure in a population study].
High systolic or diastolic blood pressure is a risk factor of left ventricular hypertrophy. However, haemodynamically speaking blood pressure is made of two components: continuous and pulsatile. Few authors have analysed the relationship between these two components and left ventricular hypertrophy. A horizontal study was conducted in 27, 687 subjects who volunteered for a medical check-up in Paris. A principal component analysis led to the estimation of two distinct parameters: a continuous pressure index (CPI) and a pulsed pressure index (PPI). The correlation between CPI and age was linear, whereas PPI was independent of age before 55 years and thereafter increased in a linear manner. This study also confirmed the importance of the relationship between the continuous component of blood pressure and electrocardiographic left ventricular hypertrophy. It is suggested that the pulsatile component might also be a risk factor of left ventricular hypertrophy independently of the continuous component level. Only a prospective study would confirm that an increase in the pulsatile component of blood pressure has a prognostic value as regards ventricular hypertrophy.
Darne
B
B
INSERM U 258, hôpital Broussais, Paris.
Girerd
X
X
Safar
M
M
Guize
L
L
D000328:Adult; D000367:Age Factors; D000368:Aged; D001794:Blood Pressure; D006332:Cardiomegaly / Q000503:physiopathology*; D003430:Cross-Sectional Studies; D004562:Electrocardiography; D005260:Female; D005602:France; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
Hypertrophie ventriculaire gauche électrique et composante pulsée de la pression artérielle dans une étude de population.