title: Sensitive model with which to detect athermal effects of non-ionizing electromagnetic radiation.
abstract: To clarify the potential of non-ionizing electromagnetic radiation to cause biological effects by athermal mechanisms, and to initiate elucidation of those mechanisms, a model system amenable to scrutiny at the molecular level has been designed and characterized. Assessment of beta-galactosidase activity in E. coli JM101 containing the plasmid pUC8 provides a sensitive assay with many important advantages. The ability to examine at the molecular level each of the processes involved in producing beta-galactosidase should permit elucidation of the molecular mechanism(s) that give rises to an observed effect.
authors.affiliation: Jackson Laboratory, Bar Harbor, ME 04609.
authors.forename: J D
authors.initials: JD
authors.lastname: Saffer
authors.forename: L A
authors.initials: LA
authors.lastname: Profenno
mesh_terms: D000818:Animals; D004574:Electromagnetic Fields; D055590:Electromagnetic Phenomena; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics / Q000528:radiation effects*; D005696:Galactosidases / Q000528:radiation effects*; D008954:Models, Biological; D010957:Plasmids / Q000528:radiation effects*; D014162:Transfection; D001616:beta-Galactosidase / Q000378:metabolism / Q000528:radiation effects*
chemical_list: D005696:Galactosidases; D001616:beta-Galactosidase