title: Abnormalities in erythrocyte membrane band 3 in chronic myelogenous leukemia.
abstract: The anion transport activities of erythrocytes from patients with chronic myelogenous leukemia (CML) and normal donors were comparable. In CML erythrocytes, significant reduction in the number of ankyrin-binding sites, present in the cytoplasmic domain of band 3, may lead to partial loss of cytoskeletal anchorage to the bilayer and account for their increased Con-A agglutinability and heat-sensitivity (Basu, J., Kundu, M., Rakshit, M.M. and Chakrabarti, P. (1988) Biochim. Biophys. Acta 945, 121-126).
authors.affiliation: Department of Chemistry, Bose Institute, India.
authors.forename: M
authors.initials: M
authors.lastname: Kundu
authors.forename: J
authors.initials: J
authors.lastname: Basu
authors.forename: M M
authors.initials: MM
authors.lastname: Rakshit
authors.forename: P
authors.initials: P
authors.lastname: Chakrabarti
mesh_terms: D017878:4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; D012856:4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid / Q000494:pharmacology; D001457:Anion Exchange Protein 1, Erythrocyte / Q000378:metabolism*; D017487:Ankyrins; D001798:Blood Proteins / Q000378:metabolism; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000097:blood*; D008565:Membrane Proteins / Q000378:metabolism; D011952:Receptors, Concanavalin A / Q000378:metabolism; D013431:Sulfates / Q000378:metabolism
chemical_list: D001457:Anion Exchange Protein 1, Erythrocyte; D017487:Ankyrins; D001798:Blood Proteins; D008565:Membrane Proteins; D011952:Receptors, Concanavalin A; D013431:Sulfates; D012856:4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; D017878:4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid