title: Successful thrombolysis on a mechanical tricuspid prosthesis.
abstract: Recombinant tissue-type plasminogen activator (rt-PA) is presently used for the treatment of different clinical entities, mostly myocardial infarction. Its use for treatment of thrombotic dysfunction of prosthetic cardiac valves is more recent and has been only rarely reported. A 33-year-old woman with a St Jude Medical prosthesis in the tricuspid position, had suffered from thrombotic dysfunction of her prosthesis for more than 2 months. She was treated with rt-PA, and after infusion of 70 mg, the prosthesis functioned normally. She showed a moderate systemic fibrinolytic state associated with mild bleeding complications.
authors.affiliation: Servicio de Medicina Intensiva, Hospital Materno Infantil, Malaga, Spain.
authors.forename: M A
authors.initials: MA
authors.lastname: Prieto Palomino
authors.forename: M J
authors.initials: MJ
authors.lastname: Ruiz de Elvira
authors.forename: F
authors.initials: F
authors.lastname: Sanchez Llorente
authors.forename: E
authors.initials: E
authors.lastname: Torrado
authors.forename: J L
authors.initials: JL
authors.lastname: Castillo
authors.forename: N
authors.initials: N
authors.lastname: Gonzalez de Vega
authors.forename: A
authors.initials: A
authors.lastname: Garijo Galve
mesh_terms: D000328:Adult; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D011183:Postoperative Complications / Q000188:drug therapy; D011994:Recombinant Proteins / Q000627:therapeutic use; D013927:Thrombosis / Q000188:drug therapy*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
chemical_list: D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator