title: Minor salivary gland tumors of the lip and buccal mucosa.
abstract: Between 1944 and 1985, 50 patients with minor salivary gland tumors of the lip and buccal mucosa were treated at M.D. Anderson Cancer Center: 19 with lip and 31 with buccal mucosa tumors. The male-to-female ratios were 2.8:1 for lip and 1:2.9 for the buccal mucosa tumors. Patient age at presentation ranged from 18 to 98 years with a median of 55 years. Treatment consisted of surgery alone for 28 patients, radiotherapy in 9 patients, and combined therapy for 13. Adenoid cystic carcinoma was the predominant histologic type, accounting for 21 (42%) tumors. Risk for recurrence was influenced by histology, the presence of perineural invasion, and the location of the primary tumor. Six patients developed recurrent disease; all six had adenoid cystic carcinoma. The therapeutic approach and the rationale for combined treatment of these neoplasms are discussed.
authors.affiliation: Department of Head and Neck Surgery, University of Texas M.D. Anderson Cancer Center, Houston 77030.
authors.forename: R S
authors.initials: RS
authors.lastname: Weber
authors.forename: J M
authors.initials: JM
authors.lastname: Palmer
authors.forename: A
authors.initials: A
authors.lastname: el-Naggar
authors.forename: M D
authors.initials: MD
authors.lastname: McNeese
authors.forename: O M
authors.initials: OM
authors.lastname: Guillamondegui
authors.forename: R M
authors.initials: RM
authors.lastname: Byers
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003528:Carcinoma, Adenoid Cystic / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008048:Lip Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa; D009062:Mouth Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D012468:Salivary Gland Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D012469:Salivary Glands / Q000601:surgery*; D012470:Salivary Glands, Minor / Q000601:surgery*