Reproducibility of quantitative 99Tcm-MAG 3 measurements in rats.
Repetitive quantitative renal extraction studies of 99Tcm-MAG 3, performed in nine rats, demonstrated excellent reproducibility of successive measurements. These results are better than with 99Tcm-DTPA, due to the higher renal extraction of the 99Tcm-MAG 3. The % of renal uptake 10 min after the injection was not influenced by the elapsed time between the end of the 99Tcm-MAG 3 preparation and its i.v. administration.
Tondeur
M
M
Department of Radioisotopes, Saint Pierre Hospital, Free Universities, Brussels, Belgium.
Piepsz
A
A
Jeghers
O
O
Froideville
J L
JL
Ham
H R
HR
D000818:Animals; D007668:Kidney / Q000000981:diagnostic imaging* / Q000378:metabolism; D008297:Male; D008657:Metabolic Clearance Rate; D009842:Oligopeptides / Q000493:pharmacokinetics*; D009942:Organometallic Compounds / Q000493:pharmacokinetics*; D051381:Rats; D011919:Rats, Inbred Strains; D017263:Technetium Tc 99m Mertiatide; D014055:Tomography, Emission-Computed
D009842:Oligopeptides; D009942:Organometallic Compounds; D017263:Technetium Tc 99m Mertiatide