[The granulomatous inflammation in bacterial infections].
The relevance of the granuloma to protection against intracellular pathogens has been recognized for a long time. More recently, it has become clear that the cell interactions which take place in a granuloma are highly complex. It appears that not only activation of antibacterial function in infected macrophages by helper T cells, but also lysis of infected host cells is of importance and that a coordinated interplay between different populations of T cells and mononuclear phagocytes is required for effective host resistance.
Kaufmann
S H
SH
Institut für Medizinische Mikrobiologie und Immunologie, Universität Ulm.
D000818:Animals; D001424:Bacterial Infections / Q000276:immunology*; D006099:Granuloma / Q000276:immunology*; D006801:Humans; D008262:Macrophage Activation; D008264:Macrophages / Q000276:immunology; D010586:Phagocytes / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology
Die granulomatöse Entzündung bei bakteriellen Infektionen.