title: Alterations in transformation efficiency by the ADPRT-inhibitor 3-aminobenzamide are oncogene specific.
abstract: The ADPRT inhibitor 3-aminobenzamide inhibits transformation of NIH 3T3 cells by the ras, v-src, v-mos and v-raf oncogenes. No effect was observed on transformation by v-fos while the transforming efficiency of SV40 DNA was increased approximately two-fold. The effect on the transformation by the ras gene occurs between days 3 and 7 of the transfection.
authors.affiliation: Department of Radiation and Cellular Oncology, University of Chicago, IL 60637.
authors.forename: A M
authors.initials: AM
authors.lastname: Diamond
authors.forename: C J
authors.initials: CJ
authors.lastname: Der
authors.forename: J L
authors.initials: JL
authors.lastname: Schwartz
mesh_terms: D001549:Benzamides / Q000494:pharmacology*; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D002472:Cell Transformation, Viral / Q000187:drug effects; D009857:Oncogenes; D013539:Simian virus 40
chemical_list: D001549:Benzamides; C025160:3-aminobenzamide