title: [Comparison of immunoenzymatic staining technique (IEST), double gluing strip circumoval precipitin test (DGS-COPT) and conventional circumoval precipitin test (CV-COPT) for diagnosis of schistosomiasis japonica].
abstract: IEST, DGS-COPT and CV-COPT using lyophilized ova of schistosoma japonicum were performed on sera from 120 cases of schistosomiasis japonica, 120 cases of schistosomiasis japonica 3-8 years after being cured with praziquantel and 120 healthy individuals by single-blind method. The sensitivity and specificity of IEST was 91.7% and 95.8% respectively which were significantly higher than that of both DGS-COPT and CV-COPT. The negative conversion rate of cured patients was 70.8% with IEST, 80.8% with DGS-COPT and 81.7% with CV-COPT. The results showed that IEST has higher diagnostic value for schistosomiasis than both COPT. DGS-COPT has the same diagnostic value as CV-COPT, however, it was easy to perform and time-saving, thus it might be applied in the fields for practical purposes.
authors.forename: Y H
authors.initials: YH
authors.lastname: Li
authors.forename: Y D
authors.initials: YD
authors.lastname: Hu
authors.forename: W M
authors.initials: WM
authors.lastname: Xu
authors.forename: G B
authors.initials: GB
authors.lastname: Yang
authors.forename: S L
authors.initials: SL
authors.lastname: Yin
authors.forename: W
authors.initials: W
authors.lastname: Gong
authors.forename: J Y
authors.initials: JY
authors.lastname: Zhu
authors.forename: Z Q
authors.initials: ZQ
authors.lastname: Wu
authors.forename: W
authors.initials: W
authors.lastname: Luo
mesh_terms: D000818:Animals; D006801:Humans; D007124:Immunoenzyme Techniques; D051379:Mice; D011223:Praziquantel / Q000627:therapeutic use; D011233:Precipitin Tests / Q000379:methods; D012554:Schistosomiasis japonica / Q000175:diagnosis* / Q000188:drug therapy; D016037:Single-Blind Method
chemical_list: D011223:Praziquantel