title: Serum enzymes in head and neck cancer. IV: 5-nucleotidase.
abstract: Serum 5-nucleotidase levels have been estimated in a group of 50 patients with head and neck cancer. The mean value was significantly higher in patients compared to the controls. In patients with non-malignant growths, the activity was comparable with the controls. The increase was higher in patients with proliferative lesions than those with ulcerative growths. Enzyme activity was found to be increased with the advancement in the stage of cancer. The rise was comparatively higher in patients with cervical metastasis. After radiotherapy, a gradual and significant reduction of serum 5-nucleotidase activity was observed.
authors.affiliation: Department of Biochemistry, Medical College, Rohtak, India.
authors.forename: H
authors.initials: H
authors.lastname: Lal
authors.forename: L
authors.initials: L
authors.lastname: Kumar
authors.forename: G S
authors.initials: GS
authors.lastname: Kohli
authors.forename: A
authors.initials: A
authors.lastname: Sharma
authors.forename: H
authors.initials: H
authors.lastname: Goel
mesh_terms: D015720:5'-Nucleotidase; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006258:Head and Neck Neoplasms / Q000201:enzymology* / Q000473:pathology / Q000532:radiotherapy; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D009708:Nucleotidases / Q000097:blood*
chemical_list: D009708:Nucleotidases; D015720:5'-Nucleotidase