[Genetic factors as determinants of drug response].
Pharmacogenetics deals with the influence of genetic factors upon the response to drugs. Therapeutic and side effects are affected by pharmacokinetic and pharmacodynamic changes. Classic examples are presented, in particular those concerning mechanisms of oxidation, acetylation and hydrolysis. The impact of this discipline on therapeutics is discussed.
Ligueros
M
M
Saavedra
H
H
Ligueros
M
M
Cruz-Coke
R
R
D004358:Drug Therapy; D005819:Genetic Markers; D006801:Humans; D010597:Pharmacogenetics
D005819:Genetic Markers
Factores genéticos como determinantes de la respuesta a fármacos.