title: [A pilot study on the effect of atrial natriuretic peptide on intraocular pressure in the human].
abstract: The presence of receptors for atrial natriuretic factor (HANaP) on the ciliary body leads to the conclusion that HANaP may play a role in the regulation of intraocular pressure. In two groups of patients (each group consisted of ten patients) the injection of 100 mg HANaP was followed by a significant lowering of the intraocular pressure. This effect could be seen over a period of 4 h. The intraocular pressure was reduced by about 25% of the baseline pressure.
authors.forename: D B
authors.initials: DB
authors.lastname: Goldmann
authors.forename: N
authors.initials: N
authors.lastname: Waubke
mesh_terms: D009320:Atrial Natriuretic Factor / Q000627:therapeutic use*; D002387:Cataract Extraction; D005902:Glaucoma, Open-Angle / Q000188:drug therapy*; D006801:Humans; D007275:Injections, Intravenous; D007429:Intraocular Pressure / Q000187:drug effects*; D010865:Pilot Projects; D011183:Postoperative Complications / Q000188:drug therapy*
chemical_list: D009320:Atrial Natriuretic Factor
vernacular_title: Pilotstudie zur Wirkung des atrialen natriuretischen Peptids auf den Augeninnendruck beim Menschen.