[Canthaxanthin retinopathy and macular pucker].
Canthaxanthine retinopathy is a crystalline retinopathy following oral ingestion of canthaxanthine-containing drugs. We describe the clinical course of a patient with canthaxanthine retinopathy and a preexisting idiopathic macular pucker. The ultrastructural findings of the macular pucker removed by vitreoretinal surgery are demonstrated. Granular material and lipid-like droplets, not usual for a macular pucker, are the major findings in this membrane. There is evidence that the granular material consists of canthaxanthine deposits, phagozytized by the cells of the epiretinal membrane.
Bopp
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Département d'ophtalmologie, Medical University, Lübeck, West Germany.
el-Hifnawi
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Laqua
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D000368:Aged; D000975:Antioxidants / Q000627:therapeutic use; D016644:Canthaxanthin; D002338:Carotenoids / Q000009:adverse effects / Q000031:analogs & derivatives*; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D008266:Macula Lutea; D008566:Membranes / Q000648:ultrastructure; D008854:Microscopy, Electron; D012160:Retina / Q000648:ultrastructure*; D012164:Retinal Diseases / Q000139:chemically induced* / Q000150:complications / Q000473:pathology
D000975:Antioxidants; D002338:Carotenoids; D016644:Canthaxanthin
Rétinopathie à la canthaxantine et syndrome de Jaffe.