[Normal term placentae: type of collagen and its disposition around fetal blood vessels detected with the Picro sirius technique].
The chorionic villi tissue of normal term human placentae is made of a highly fibrous extracellular matrix. An increasing amount of fibrous tissue is seen as gestation advances, phenomenon referred as organ aging. Electron microscopy reveals many collagen fibrils close to fibroblasts between the trophoblast and the fetal capillary vessels. A characteristic 67 nm transverse striation produced by the intermixing of tropocollagen and collagen types 1 and 3 is observed. Picrosirius staining under polarized light allowed us to detect abundant type 1 collagen fibers. These were randomly distributed in the stroma but concentrically order around the blood vessels.
Bosco
C
C
Manríquez
F
F
Molina
R
R
Araya
J
J
D002824:Chorionic Villi / Q000648:ultrastructure*; D003094:Collagen / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D010920:Placenta / Q000737:chemistry*; D011247:Pregnancy
D003094:Collagen
Placentas normales de término: tipo de colágeno y su disposición en la vecindad de los vasos sanguineos fetales detectados en la técnica Picro sirius.