[The use of clomiphene and menotropins as inducers of multiple follicular growth in a program of in vitro fertilization].
In our IVF & related techniques program, clomiphene 50 mg was used from days 2 to 6 of the cycle in 20 patients and 20 cycles. (17 IVF patients and 3 GIFT patients) menotropins were also used in 2 different schemes: a) 2 ampules in alternated days (12 cases) and b) one ampule daily (8 cases). The patients with the daily scheme required lesser total dose of menotropins and developed higher estradiol levels, although this had none statistic significance, and they also developed a greater number of follicles. There were 16 laparoscopies for ovum capture and 53 oocytes were retrieved (30.2% mature) 10 oocytes were from the GIFT patients. 16 oocytes were fertilized and 8 cleaved. There was only one pregnancy from and IVF patient with the alternated scheme that ended with a first trimester abortion.
García Luna
A
A
Gorozpe
J
J
Fuentes
E
E
Murrieta
S
S
Téllez
J
J
González Diddi
M
M
D000328:Adult; D002996:Clomiphene / Q000008:administration & dosage*; D004958:Estradiol / Q000097:blood; D005260:Female; D005307:Fertilization in Vitro; D015181:Gamete Intrafallopian Transfer; D006801:Humans; D008596:Menotropins / Q000008:administration & dosage*; D009865:Oocytes / Q000254:growth & development; D006080:Ovarian Follicle / Q000502:physiology; D010062:Ovulation Induction / Q000379:methods*; D015053:Zygote / Q000254:growth & development
D002996:Clomiphene; D004958:Estradiol; D008596:Menotropins
Empleo de clomifeno y menotropinas como inductores de crecimiento folicular múltiple en un programa de fertilización in vitro.