[The effect of an agluten diet on cellular immunity in adult patients with celiac disease].
A total of 45 patients with Gee's disease of adults were followed up in the time course of 6 months to 3 years. In untreated patients the number of T-lymphocytes was decreased both at the expense of T-helpers and, especially, of T-suppressors. Lymphokine-producing activity of T-lymphocytes, according to the production degree of the mediator, inhibiting monocyte adherence, increases after gliadin-treatment of the immuno-competent cells, that leads to monocyte adhesion decrease. In patients strictly keeping the agluten diet the cellular immunity parameters return to normal. Decreased monocyte adhesion remains up to a year. In those who do not strictly keep the agluten diet the cellular immunity disorders are retained and become more pronounced than in the untreated patients.
Gudkov
R B
RB
Ekisenina
N I
NI
Kurochkina
O K
OK
Chanturiia
Zh A
ZhA
D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology; D002446:Celiac Disease / Q000178:diet therapy* / Q000276:immunology; D004032:Diet; D005983:Glutens / Q000008:administration & dosage*; D006801:Humans; D007111:Immunity, Cellular; D008222:Lymphokines / Q000096:biosynthesis; D013601:T-Lymphocytes / Q000276:immunology; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
D008222:Lymphokines; D005983:Glutens
Vliianie agliutenovoĭ diety na pokazateli kletochnogo immuniteta u bol'nykh tseliakieĭ vzroslykh.