title: [Hemodynamic vertebrobasilar insufficiency demonstrated by chronic oligemic cerebral flow and cerebellar ataxia: two new concepts].
abstract: We propose in the paper of the concept of nuclear hemodynamic vertebrobasilar insufficiency, defined as an oligemic blood flow lower than 35 ml/100 g/min. in the brain stem-cerebellum zone, when using the method of inhalation of 133Xe. In 15 patients, the neurophysiologic manifestations included intermittent symptoms. We describe here permanent neurophysiologic motor disturbances: extrapyramidal Dopa sensitive syndrome (2/15), chronic cerebellar ataxia (12/15), often associated with cerebellar atrophy (8/12). The concept of chronic oligemic cerebellar ataxia, corresponding to selective neuronal death and/or neurochemical failure, is proposed.
authors.affiliation: Service de Neurologie B, Faculté Alexis-Carrel, Hôpital neurologique, Lyon.
authors.forename: P
authors.initials: P
authors.lastname: Trouillas
authors.forename: B
authors.initials: B
authors.lastname: Philippon
authors.forename: N
authors.initials: N
authors.lastname: Nighoghossian
mesh_terms: D000280:Administration, Inhalation; D002524:Cerebellar Ataxia / Q000503:physiopathology*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D002908:Chronic Disease; D006439:Hemodynamics; D006801:Humans; D014715:Vertebrobasilar Insufficiency / Q000503:physiopathology*; D014980:Xenon Radioisotopes / Q000008:administration & dosage
chemical_list: D014980:Xenon Radioisotopes
vernacular_title: Insuffisance vertébro-basilaire hémodynamique démontrée par les débits cérébraux et ataxie cérébelleuse oligémique chronique: deux nouveaux concepts.