title: [ICO-35 monoclonal antibodies to the antigen of acute lymphoblastic leukemia].
abstract: ICO-35 monoclonal antibodies (Mabs) were produced following BALB/c mouse immunization with peripheral blood cells from a patient with lymphoid type of chronic myeloid leukemia in blast crisis (SML BC) ICO-35. Mabs detect antigen on CD10-positive cells from patients with acute lymphoblastic leukemia, CML BC, CD10-positive cells of Reh line and are not bound to other cells. Comparative studies of reactivity of ICO-35 and K 503 Mabs to CD10 antigen revealed their similarity. However, in contrast to K503 ICO-35 Mabs do not react with granulocytes.
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Baryshnikov
authors.forename: N N
authors.initials: NN
authors.lastname: Tupitsyn
authors.forename: O V
authors.initials: OV
authors.lastname: Korotkova
authors.forename: Z G
authors.initials: ZG
authors.lastname: Kadagidze
authors.forename: E
authors.initials: E
authors.lastname: Dostot
authors.forename: M
authors.initials: M
authors.lastname: Shmidt
authors.forename: L
authors.initials: L
authors.lastname: Boumsell
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000943:Antigens, Differentiation / Q000276:immunology*; D000951:Antigens, Neoplasm / Q000276:immunology*; D001853:Bone Marrow / Q000276:immunology; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C; D015260:Neprilysin; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D000943:Antigens, Differentiation; D000951:Antigens, Neoplasm; D015260:Neprilysin
vernacular_title: Monoklonal'nye antitela IKO-35 k antigenu ostrogo limfoblastnogo leĭkoza.