title: [Perfusion of prostaglandins in the cervix uteri. A new method of cervical maturation after premature rupture of the membranes].
abstract: Many authors consider that using prostaglandins is the best way of obtaining adequate maturation of the cervix uteri before induction of labour; however, in case of premature rupture of the membranes the conventional methods can seldom be used. An original technique for this relatively rare situation is presented, consisting of an intracervical infusion of prostaglandin F2-alpha at the initial rate of 0.3 mg/hour. Details are given of the technique as well as of the results obtained in a preliminary study of 10 patients. With a mean 7.5 mg total dose of prostaglandin F2-alpha, the mean durations of maturation and delivery were 15 and 20 hours respectively. No infection developed and the procedure was well tolerated by the patients. Nevertheless, this technique should be reserved to those cases where conventional methods cannot be used.
authors.affiliation: Département de Gynécologie-Obstétrique et de la Reproduction, CHU, Clinique du Beffroi, Tours.
authors.forename: G
authors.initials: G
authors.lastname: Body
authors.forename: F
authors.initials: F
authors.lastname: Pierre
authors.forename: J H
authors.initials: JH
authors.lastname: Soutoul
mesh_terms: D002584:Cervix Uteri / Q000187:drug effects*; D015237:Dinoprost / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D005322:Premature Rupture of Fetal Membranes; D006801:Humans; D007751:Labor, Induced / Q000379:methods; D010477:Perfusion / Q000379:methods*; D011247:Pregnancy
chemical_list: D015237:Dinoprost
vernacular_title: Perfusion de prostaglandines dans le col. Une nouvelle méthode de maturation cervicale après rupture prématurée des membranes.