Prednisolone purpura.
Corticosteroids, though known to act effectively against allergy and hypersensitivity, may themselves produce such reactions, ranging from urticaria to anaphylaxis. A middle-aged man with collagen vascular disease developed purpuric rash on repeated administration of steroids. This acute purpuric reaction with sequential colour changes is different than the more common senile purpura-like lesions induced by intake of steroids. It is also different than the purpuric lesions associated with collagen vascular disease per se. The present case favours an allergic aetiology.
Singhvi
G R
GR
Chordiya
A V
AV
D000328:Adult; D003240:Connective Tissue Diseases / Q000188:drug therapy*; D003875:Drug Eruptions / Q000209:etiology*; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage / Q000009:adverse effects*; D011693:Purpura / Q000139:chemically induced*
D011239:Prednisolone