[Preliminary study on mutagenicity of MeIQ and extracts of fried fish and antimutagenicity of some dietary factors].
2-amino-3,4-dimethylimidazo (4,5-f) quinoline (MeIQ) and extracts of fried fish showed a strong mutagenicity as reflected backward mutation in Salmonella typhimurium. Significant inhibitory effects on mutagenicity induced by MeIQ or extracts of fried fish were found by simultaneous treatment with extracts of fresh vegetables, fruits and especially green tea antioxidants. The results indicated that some mutagens and/or carcinogens might be produced during high temperature cooking of some animal meats. The frequent intake of fresh vegetables, fruits and green tea might be beneficial in the prevention of human cancer.
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D000818:Animals; D005399:Fishes; D005638:Fruit; D006358:Hot Temperature; D009152:Mutagenicity Tests; D009153:Mutagens; D010936:Plant Extracts / Q000494:pharmacology; D011804:Quinolines / Q000037:antagonists & inhibitors / Q000633:toxicity*; D051381:Rats; D013662:Tea; D014675:Vegetables
D009153:Mutagens; D010936:Plant Extracts; D011804:Quinolines; D013662:Tea; C036989:2-amino-3,4-dimethylimidazo(4,5-f)quinoline