Serotonin-dependent (Na+,K+)ATPase in kindled rats: a study in various brain regions.
Serotonin (5-HT) modulation of brain (Na+,K+)ATPase, has recently been proposed. Activation curves of the enzyme activity dependent on 5-HT concentration have previously been observed in various brain regions of normal rats. In the present study, we report the absence of 'normal' (Na+,K+)ATPase response to 5-HT in cerebral cortex, striatum and diencephalon of kindled rats.
Hernández
J
J
Department of Physiology, Centro de Investigación y de Estudios Avanzados del IPN, Zacatenco, Mexico.
Condés-Lara
M
M
D000818:Animals; D001921:Brain / Q000201:enzymology* / Q000503:physiopathology; D007696:Kindling, Neurologic; D051381:Rats; D011919:Rats, Inbred Strains; D012640:Seizures / Q000201:enzymology* / Q000503:physiopathology; D012701:Serotonin / Q000494:pharmacology*; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*
D012701:Serotonin; D000254:Sodium-Potassium-Exchanging ATPase