title: [The TRH test using the Bulgarian preparation Protilerin in the diagnosis of hyperthyroidism].
abstract: The stimulation test--TRH test was carried out with the Bulgarian drug "Protilerin" in 63 patients (Basedow's disease--53 patients, basedoid goiter--5 patients, infiltrative ophthalmopathy--5 patients) and in 20 healthy controls. The healthy controls showed normal reaction to the stimulation. All patients with hyperthyroidism showed a suppressed response to the stimulation. In two of the patients with euthyroid infiltrative ophthalmopathy the response was similar to that of the healthy controls. The Bulgarian drug Protilerin is suitable for the performance of the TRH test in the diagnosis of hyperthyroidism.
authors.forename: D
authors.initials: D
authors.lastname: Manolov
authors.forename: B
authors.initials: B
authors.lastname: Zakharieva
authors.forename: G
authors.initials: G
authors.lastname: Lazarov
authors.forename: A
authors.initials: A
authors.lastname: Manov
authors.forename: V
authors.initials: V
authors.lastname: Vŭrbanov
mesh_terms: D000328:Adult; D004341:Drug Evaluation; D005067:Euthyroid Sick Syndromes / Q000175:diagnosis; D005128:Eye Diseases / Q000175:diagnosis; D005260:Female; D006111:Graves Disease / Q000175:diagnosis; D006801:Humans; D006980:Hyperthyroidism / Q000175:diagnosis*; D008297:Male; D013973:Thyrotropin-Releasing Hormone
chemical_list: D013973:Thyrotropin-Releasing Hormone
vernacular_title: TRKh test s bŭlgarskiia preparat protilerin v diagnostikata na khipertireoidizma.