[In vivo 31P magnetic resonance spectroscopy and MRI in patients with superficial tumors].
Simultaneous 31P-MR spectroscopy (MRS) and MR imaging (MRI) of 10 patients suffering from superficial tumours like carcinoma, lymphoma and adenoma, revealed significantly enhanced concentrations of phosphomonoester, phosphodiester and inorganic phosphorus in the tumour, whereas the concentration of phosphocreatine was lower in comparison to muscle tissue. In all tumours the pH showed a slight alkaline shift. The existing of necrotic regions detected by MRI was accompanied by an increase of inorganic phosphorus in the spectra. A follow-up study of a patient with a lymphoma during chemotherapy showed a tumour regression, whereas the spectra indicated a continuous approach of tumour values to the muscle values.
Vogl
T
T
Radiologische Klinik der Universität München.
Peer
F
F
Reiman
V
V
Holtmann
S
S
Rennschmid
C
C
Weber
H
H
Hahn
D
D
Lissner
J
J
D003287:Contrast Media; D005682:Gadolinium; D019786:Gadolinium DTPA; D006258:Head and Neck Neoplasms / Q000032:analysis / Q000175:diagnosis*; D006801:Humans; D008207:Lymphatic Metastasis; D008279:Magnetic Resonance Imaging / Q000379:methods; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D009942:Organometallic Compounds; D009943:Organophosphorus Compounds / Q000032:analysis; D004369:Pentetic Acid; D010710:Phosphates / Q000032:analysis; D010761:Phosphorus Radioisotopes; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
D003287:Contrast Media; D009942:Organometallic Compounds; D009943:Organophosphorus Compounds; D010710:Phosphates; D010761:Phosphorus Radioisotopes; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA
In vivo 31P Magnetresonanz Spektroskopie und MRI bei Patienten mit oberflächlich gelegenen Tumoren.