[The effect of an immune antibacterial plasma and a donor leukocyte mass on the immune system of patients with suppurative-septic processes].
The influence of immune antistaphylococcal, anti-Proteus and anti-Pseudomonas aeruginosa plasma and donor leukocyte mass on some humoral and cell-mediated immunity characteristics in patients with purulent and septic diseases has been studied. The study has shown that treatment with immune plasma leads to an increase in the amount of circulating T lymphocytes and in the concentration of IgA, IgM and IgG, to the activation of phagocytosis and to an increase in the titers of the corresponding antimicrobial antibodies simultaneously with a decrease in the content of bacterial antigens in the blood serum. Treatment with donor leukocyte mass has also been found to lead to an increase in the concentration of T lymphocytes and immunoglobulins, to enhance the functional activity of phagocytizing neutrophils and to promote the normalization of the content of leukocytes in the peripheral blood. The use of these preparations as stimulating agents in the treatment of patients having purulent septic diseases and, simultaneously, low cell-mediated immunity characteristics is recommended.
Bulava
G V
GV
Zdanovskaia
L K
LK
Titova
T I
TI
D000907:Antibodies, Bacterial / Q000032:analysis; D000917:Antibody Formation / Q000187:drug effects / Q000276:immunology; D000942:Antigens, Bacterial / Q000032:analysis; D001782:Blood Donors; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects / Q000276:immunology; D007167:Immunotherapy / Q000379:methods; D007962:Leukocytes / Q000276:immunology*; D010949:Plasma / Q000276:immunology*; D011513:Proteus mirabilis / Q000276:immunology*; D011550:Pseudomonas aeruginosa / Q000276:immunology*; D013211:Staphylococcus aureus / Q000276:immunology*; D013492:Suppuration / Q000276:immunology / Q000628:therapy*; D013997:Time Factors
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial
Vliianie immunnoĭ antibakterial'noĭ plazmy i donorskoĭ leĭkotsitnoĭ massy na immunnuiu sistemu bol'nykh s gnoĭno-septicheskimi protsessami.