title: Impaired sweating in the diabetic neuropathic foot and its influence on skin flora.
abstract: Three groups each of 10 subjects, were defined by clinical and neurophysiological studies: diabetic with neuropathy (Group A), diabetic without neuropathy (Group B) and normal control (Group C). Sweating on the foot was quantified and the bacterial flora on the dorsum of the foot and deltoid area were examined. There were no significant differences in type of density of bacterial species found on either foot or deltoid regions between any of the three groups. Diabetics free of clinical infection have a similar skin microbial flora to non-diabetics even when sweating is seriously impaired. It is therefore unlikely that a change in the resident microbial flora is involved in the propensity of diabetic neuropathic patients to foot ulceration and infection.
authors.affiliation: Diabetes Unit, Bristol Royal Infirmary, UK.
authors.forename: P G
authors.initials: PG
authors.lastname: Newrick
authors.forename: I A
authors.initials: IA
authors.lastname: O'Brien
authors.forename: A
authors.initials: A
authors.lastname: Smart
authors.forename: R J
authors.initials: RJ
authors.lastname: Corrall
authors.forename: D C
authors.initials: DC
authors.lastname: Speller
mesh_terms: D000192:Actinomycetales / Q000302:isolation & purification; D000328:Adult; D001439:Bacteroides / Q000302:isolation & purification; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology*; D003929:Diabetic Neuropathies / Q000503:physiopathology*; D005260:Female; D005528:Foot; D006090:Gram-Negative Bacteria / Q000302:isolation & purification; D006094:Gram-Positive Bacteria / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008835:Micrococcaceae / Q000302:isolation & purification; D008875:Middle Aged; D011424:Propionibacterium / Q000302:isolation & purification; D012016:Reference Values; D012867:Skin / Q000382:microbiology* / Q000503:physiopathology; D013546:Sweating