title: Screening for cytomegalovirus antibody in a donor insemination program: difficulties in implementing The American Fertility Society guidelines.
abstract: With the recommendations of The American Fertility Society that all donors and recipients in a donor insemination programme should be screened for CMV antibody, we have documented the prevalence of CMV antibody in donors, recipients, and their partners in our clinic. Forty percent of our donors were CMV-positive, and in only 35% of the couples were both partners negative. The implications of using exclusively CMV-negative donors are examined. The necessity for further research on the detection and the transmission of various strains of CMV and the effects of cryopreservation on them is emphasized.
authors.affiliation: Harris Birthright Research Centre for Reproductive Medicine, Jessop Hospital for Women, Sheffield, United Kingdom.
authors.forename: M
authors.initials: M
authors.lastname: Chauhan
authors.forename: C L
authors.initials: CL
authors.lastname: Barratt
authors.forename: S
authors.initials: S
authors.lastname: Cooke
authors.forename: I D
authors.initials: ID
authors.lastname: Cooke
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis*; D003168:Complement Fixation Tests; D003587:Cytomegalovirus / Q000276:immunology*; D005260:Female; D005298:Fertility; D006285:Health Planning; D006287:Health Planning Guidelines; D006801:Humans; D007315:Insemination, Artificial; D007841:Latex Fixation Tests; D008297:Male; D012955:Societies, Medical
chemical_list: D000914:Antibodies, Viral