Perspectives of physostigmine as antidote by toluene intoxication.
The administration of physostigmine (0.3 mg/kg s.c.) compensated toluene intoxication in rats together with NEFA return toward the normal values. This interaction of toluene and physostigmine supports the hypothesis of NEFA functioning as moderators of the cerebral activity.
Navrátil
J
J
Sklenovský
A
A
Chmela
Z
Z
Rypka
M
M
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D005227:Fatty Acids / Q000378:metabolism; D008297:Male; D010830:Physostigmine / Q000494:pharmacology*; D011041:Poisoning / Q000188:drug therapy*; D051381:Rats; D011919:Rats, Inbred Strains; D014050:Toluene / Q000633:toxicity*
D005227:Fatty Acids; D014050:Toluene; D010830:Physostigmine