Properties of nervous tissue proteoglycans relevant to studies on Alzheimer's disease.
Our comments concern certain properties of nervous tissue proteoglycans which were not emphasized in the review by Snow and Wight, with particular attention to the proposed relation of the amyloid beta protein precursor to a heparan sulfate proteoglycan core protein.
Margolis
R U
RU
Department of Pharmacology, New York University Medical Center, NY 10016.
Margolis
R K
RK
D000544:Alzheimer Disease / Q000378:metabolism* / Q000473:pathology; D006025:Glycosaminoglycans / Q000378:metabolism*; D006497:Heparan Sulfate / Q000378:metabolism*; D006801:Humans; D009420:Nervous System / Q000378:metabolism*; D011509:Proteoglycans / Q000378:metabolism*
D006025:Glycosaminoglycans; D006497:Heparan Sulfate; D011509:Proteoglycans