Molecular analysis of HTLV-I proviral integration and T cell receptor arrangement indicates that T cells in tropical spastic paraparesis are polyclonal.
Greenberg
S J
SJ
Metabolism Branch, National Cancer Institute, Bethesda, Maryland.
Jacobson
S
S
Waldmann
T A
TA
McFarlin
D E
DE
D015139:Blotting, Southern; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D015333:Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; D015368:Human T-lymphotropic virus 1 / Q000235:genetics* / Q000276:immunology; D006801:Humans; D008297:Male; D009693:Nucleic Acid Hybridization; D015493:Paraparesis, Tropical Spastic / Q000276:immunology*; D011533:Proviruses / Q000235:genetics* / Q000276:immunology; D011948:Receptors, Antigen, T-Cell / Q000235:genetics*; D015183:Restriction Mapping; D013601:T-Lymphocytes / Q000276:immunology*
D004279:DNA, Viral; D011948:Receptors, Antigen, T-Cell