[Thrombocytopenia in a patient with hemophilia and HIV infection treated with intravenous immunoglobulin and splenectomy].
In a patient with haemophilia B who had developed immune thrombocytopenia following HIV infection, high doses of intravenous immunoglobulin were administered. The therapy brought about only a temporary rise in platelet counts. No beneficial effects were also obtained during a 3-month treatment with corticosteroids. Since there was no response to the conservative therapy, the patient was splenectomized under the cover of factor IX concentrate and the surgical procedure resulted in a complete remission of the thrombocytopenia.
Rozmysłowicz
T
T
Ziemski
J M
JM
Rudowski
W
W
Lopaciuk
S
S
D000163:Acquired Immunodeficiency Syndrome / Q000097:blood / Q000150:complications*; D000328:Adult; D002836:Hemophilia B / Q000097:blood / Q000150:complications*; D006801:Humans; D007116:Immunization, Passive; D007074:Immunoglobulin G / Q000008:administration & dosage*; D016756:Immunoglobulins, Intravenous; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D008297:Male; D010976:Platelet Count; D013921:Thrombocytopenia / Q000150:complications / Q000628:therapy*
D007074:Immunoglobulin G; D016756:Immunoglobulins, Intravenous
Małopłytkowość u chorego na hemofilie z zakazeniem HIV leczona dozylnie immunoglobulina i splenektomia.