title: [Visceral leishmaniasis in Ordubad District, Nakhichevan ASSR].
abstract: Visceral leishmaniasis (VL) focus in the Ordubad District of the Nakhichevan ASSR has become active for the last years. Complex study of the focus, performed in 1985-1987, allowed to establish the following: VL causative agent, circulating in the Ordubad District belongs to the Leishmania infantum species. It was identified by isoenzymatic analysis (for 12 enzymes) and the Adler serological test. Disease cases prevailed in the upper part of the town of Ordubad and were confined to a small area (4 adjoining streets). Little children (up to 2 years old) prevail among patients. Spatial distribution of the disease correlated with indirect EIA data on healthy urban population (3116 persons examined) and stray dogs (152 animals examined). Mean percentage of positive assay results for the titers ranging from 1:80 to 1:20 was 8.0, for human population of Ordubad, and 19.1 for the dogs. Ten Phlebotominae species were found in Ordubad and its suburbs: Phlebotomus (Laroussius) major, Ph. (L.) kandelakii, Ph. (Adlerius) halepensis, Ph. (A.) balcanicus, Ph. (Phlebotomus) papatasi, Ph. (Paraphlebotomus) sergentii, Ph. (Par.) caucasicus, Ph. (Par.) alexandri, Sergentomyia dentata, S. palestinensis. Authors suggest that stray dogs are reservoirs of infectious agents in the Ordubad focus, while Phlebotominae of the Laroussius and Adlerius subspecies are disease carriers, the disease being regarded as a Mediterranean form of visceral leishmaniasis.
authors.forename: T A
authors.initials: TA
authors.lastname: Tagi-zade
authors.forename: G B
authors.initials: GB
authors.lastname: Gasanzade
authors.forename: V M
authors.initials: VM
authors.lastname: Saf'ianova
authors.forename: G B
authors.initials: GB
authors.lastname: Shal'miev
authors.forename: E A
authors.initials: EA
authors.lastname: Gadzhibekova
mesh_terms: D000367:Age Factors; D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis; D001382:Azerbaijan; D001853:Bone Marrow / Q000469:parasitology; D003289:Convalescence; D004197:Disease Reservoirs / Q000662:veterinary; D004199:Disease Vectors; D004283:Dog Diseases / Q000453:epidemiology / Q000469:parasitology / Q000635:transmission; D004285:Dogs; D006801:Humans; D007303:Insect Vectors / Q000469:parasitology; D007893:Leishmania donovani / Q000276:immunology / Q000302:isolation & purification; D007898:Leishmaniasis, Visceral / Q000453:epidemiology* / Q000469:parasitology / Q000635:transmission / Q000662:veterinary; D010691:Phlebotomus / Q000469:parasitology; D012424:Rural Population; D014505:Urban Population
chemical_list: D000913:Antibodies, Protozoan
vernacular_title: Vistseral'nyĭ leĭshmanioz v Ordubadskom raĭone Nakhichevanskoĭ ASSR.