[Participation of beta-endorphins in organizing neuronal activity of the rabbit hypothalamic "hunger centers"].
Microiontophoretic application of beta-endorphin activated neuronal activity (48%) rather than inhibited it (38%) or had no effect whatsoever (14%) in the later hypothalamus of satiated rabbits. Naloxone inhibited the neuronal activity in 75% of the cases as well as activated it (25%), no areactive neurons having been found. The variations of latency of the interspike intervals due to the effect of beta-endorphin depended on the background activity of the neurons. The beta-endorphin--sensitive neurons seem to play a part both in neuronal mechanisms of feeding motivation and in those of satiation.
Figurov
A I
AI
Mishcheriakov
A F
AF
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D005247:Feeding Behavior / Q000187:drug effects; D006815:Hunger / Q000502:physiology*; D007031:Hypothalamus / Q000187:drug effects / Q000502:physiology*; D008297:Male; D009270:Naloxone / Q000494:pharmacology; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D011817:Rabbits; D001615:beta-Endorphin / Q000502:physiology*
D009270:Naloxone; D001615:beta-Endorphin
Uchastie beta-éndorfina v organizatsii impul'snoĭ aktivnosti neĭronov "tsentrov goloda" gipotalamusa krolikov.