[Diabetic microangiopathy. Role of capillaroscopy].
In order to evaluate the significance of ungual and conjunctival microvascular abnormalities observed in diabetics prior to retinopathy, nailfold and conjunctival capillaroscopy was performed in 20 controls and 40 insulin-dependent diabetics of the same age. The diabetics were divided into 4 groups according to their state of retinopathy: absent, incipient, non-proliferative and proliferative. No difference was found between controls and diabetics and between groups of diabetics in the frequency of conjunctiva microaneurysms and specific nailfold microangiopathy, nor even in that of the so-called characteristic "fish shoal" image. The percentage of abnormalities detected was concordant with the results of previous studies in diabetics (12.5 per cent of non-specific organic microangiopathy), but it was 2 to 4 times higher than the frequency usually found in non-diabetic controls. This discrepancy could be due to the method used, since in contrast with earlier studies the operator did not know whether the subject was diabetic or not and was unaware of the patient's retina state. In the absence of other blind and prospective studies, capillaroscopic examination for diabetic microangiopathy should be reserved strictly to clinical research.
Mouthon
J M
JM
Service de Médecine interne, Centre hospitalier universitaire Pitié-Salpêtrière, Paris.
Bosquet
F
F
Grimaldi
A
A
Wechsler
B
B
Thervet
F
F
Godeau
P
P
D000293:Adolescent; D000328:Adult; D002196:Capillaries; D003228:Conjunctiva / Q000098:blood supply; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis; D003925:Diabetic Angiopathies / Q000175:diagnosis*; D003930:Diabetic Retinopathy / Q000175:diagnosis; D004311:Double-Blind Method; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009262:Nails / Q000098:blood supply
Microangiopathie diabétique. Place de la capillaroscopie.