title: The development of lymphatic follicles in the omentum after intraperitoneal stimulation of rats.
abstract: China ink and typhoid vaccine were used as peritoneal stimuli injected in single doses. The subsequent omental reaction was studied after several time intervals: 6 and 12 hours, 1, 2, 3, 4 and 8 days, 3 and 6 weeks. The omental reaction featured as lymphatic nodules connected to milky spots was compared with a primary immune response. The ultrastructure and development of the characteristic cells (lymphocytes, lymphoblasts, dendritic reticulum cells, tingible body macrophages and plasma cells) was investigated throughout the period from 6 h to 6 weeks. A special attention was devoted to ultrastructural and functional features of plasma cells.
authors.forename: E
authors.initials: E
authors.lastname: Mandache
authors.forename: A
authors.initials: A
authors.lastname: Negoescu
authors.forename: E
authors.initials: E
authors.lastname: Moldoveanu
mesh_terms: D000818:Animals; D002244:Carbon; D004396:Coloring Agents / Q000494:pharmacology; D007274:Injections, Intraperitoneal; D008198:Lymph Nodes / Q000187:drug effects* / Q000276:immunology / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D009852:Omentum / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains; D013268:Stimulation, Chemical; D013997:Time Factors; D014436:Typhoid-Paratyphoid Vaccines / Q000008:administration & dosage
chemical_list: D004396:Coloring Agents; D014436:Typhoid-Paratyphoid Vaccines; C028433:chinese ink; D002244:Carbon