title: [Presynaptic action of tubocurarine during frequent stimulation of a motor nerve].
abstract: The dependence of the end-plate potentials inhibition upon the prevention of the muscle twitches either by tubocurarine, or alpha-neurotoxin, or cutting of the fibers was studied during nerve tetanization in the frog isolated cutaneous pectoral muscles. The decrease in end-plate potentials in the course of tetanization was the strongest under the effect of tubocurarine. The latter seems to inhibit the quantum release of acetylcholine during the nerve tetanization.
authors.forename: V M
authors.initials: VM
authors.lastname: Grigor'ev
authors.forename: A F
authors.initials: AF
authors.lastname: Danilov
authors.forename: A I
authors.initials: AI
authors.lastname: Skliarov
mesh_terms: D000109:Acetylcholine / Q000378:metabolism; D000818:Animals; D066298:In Vitro Techniques; D008297:Male; D009469:Neuromuscular Junction / Q000187:drug effects* / Q000502:physiology; D011895:Rana ridibunda; D011950:Receptors, Cholinergic / Q000187:drug effects*; D013569:Synapses / Q000187:drug effects*; D009435:Synaptic Transmission / Q000187:drug effects; D014403:Tubocurarine / Q000494:pharmacology*
chemical_list: D011950:Receptors, Cholinergic; D000109:Acetylcholine; D014403:Tubocurarine
vernacular_title: Presinapticheskoe deĭstvie tubokurarina pri chastoĭ stimuliatsii dvigatel'nogo nerva.