[Chagas' disease in patients with renal transplantation].
After observing a fatal chagasic infection in a renal transplant recipient we investigated Chagas disease in 84 recipients of renal transplants. The indirect hemagglutination test was used for screening and xenodiagnosis followed in positive cases, along with ECG and gastrointestinal X ray series. Nine cases were detected (10%); parasites were found in the blood of 6 of them (66%). No patient had cardiac or gastrointestinal involvement. Patients with a positive serology were treated with nifurtimox (2) or benzonidazol (7); xenodiagnosis every 6 months up to 67 months remains negative in these patients. Blood transfusions are suspected as the mechanism for infection in these cases.
Thambo
S
S
Passalacqua
W
W
Van Cauwelaert
R
R
Lazcano
F
F
D000293:Adolescent; D000328:Adult; D014355:Chagas Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000635:transmission; D005260:Female; D006801:Humans; D007108:Immune Tolerance; D016030:Kidney Transplantation; D008297:Male; D009547:Nifurtimox / Q000627:therapeutic use; D009593:Nitroimidazoles / Q000627:therapeutic use; D012698:Serologic Tests; D065227:Transfusion Reaction; D014344:Trypanocidal Agents / Q000627:therapeutic use
D009593:Nitroimidazoles; D014344:Trypanocidal Agents; D009547:Nifurtimox; C009999:benzonidazole
Enfermedad de Chagas en trasplantados renales.