Hyperplastic cellular components of a hemangiopericytoma. An ultrastructural study.
Based on ultrastructural features of cellular components of a hemangiopericytoma, hyperplastic cells are classifiable into fibroblast-like (group I), endotheloid (group II) and pericyte-like (group III) cells. The transformation of the group I cells to the group II, or to the group III cells, is pronounced in our electron micrographs and this may imply that the group I cell is the principal cell of origin in this neoplasm. The smooth muscle-like (group IV) cells comprising the media of the arteries and veins in this neoplasm may represent modified, possibly de-differentiated smooth muscle cells reacted to the neoplastic proliferation of the surrounding adventitial (group I) cells.
Maruyama
T
T
Department of Dermatology, University of Occupational and Environmental Health, School of Medicine, Kitakyushu, Japan.
Nomiyama
T
T
Asahi
M
M
Mori
N
N
Ono
E
E
Kawahara
A
A
Fujimoto
S
S
D000328:Adult; D004727:Endothelium / Q000648:ultrastructure; D005260:Female; D005347:Fibroblasts / Q000648:ultrastructure; D006393:Hemangiopericytoma / Q000098:blood supply / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D008854:Microscopy, Electron; D009130:Muscle, Smooth / Q000473:pathology / Q000648:ultrastructure; D012878:Skin Neoplasms / Q000098:blood supply / Q000473:pathology* / Q000648:ultrastructure