[Structural-functional properties of erythrocyte membranes in patients with infectious-allergic bronchial asthma].
A decrease in activity of Ca2(+)-ATPase and activation of Na+, K(+)-ATPase, correlating with elevation in content of phosphatidyl inositol and phosphatidyl serine, were detected in erythrocyte membranes of patients with the infectional-allergic form of bronchial asthma. Microviscosity of the erythrocyte membranes, estimated by fluorescence spectra of pyrene, was not altered, while negative charge as shown by ANS- fluorescence, was slightly increased on the membrane surface. Euphylline, intal, levamizole and glucocorticosteroid were found to regulate the ATPases activity in vivo and in vitro.
Borodin
E A
EA
Landyshev
Iu S
IuS
Savel'eva
M V
MV
D000251:Adenosine Triphosphatases / Q000097:blood; D001249:Asthma / Q000097:blood* / Q000188:drug therapy; D001809:Blood Viscosity; D004789:Enzyme Activation; D004910:Erythrocyte Membrane / Q000032:analysis* / Q000187:drug effects / Q000201:enzymology; D006801:Humans; D008563:Membrane Lipids / Q000097:blood; D010743:Phospholipids / Q000097:blood
D008563:Membrane Lipids; D010743:Phospholipids; D000251:Adenosine Triphosphatases
Strukturno-funktsional'nye svoĭstva membran éritrotsitov u bol'nykh infektsionno-allergicheskoĭ bronkhial'noĭ astmoĭ.