title: Comparative susceptibility of Mycoplasma pneumoniae to erythromycin, ciprofloxacin, and lomefloxacin.
abstract: Lomefloxacin was found to be comparable to ciprofloxacin in its ability to inhibit the in vitro growth of Mycoplasma pneumoniae (MIC range 2-8 mcg/ml), but it was significantly less active than erythromycin. Although 30 different strains from widely differing geographic areas and isolation time periods were examined, no macrolide-resistant strains were observed.
authors.affiliation: Department of Microbiology, University of Alabama, Birmingham 35294.
authors.forename: G H
authors.initials: GH
authors.lastname: Cassell
authors.forename: K B
authors.initials: KB
authors.lastname: Waites
authors.forename: M S
authors.initials: MS
authors.lastname: Pate
authors.forename: K C
authors.initials: KC
authors.lastname: Canupp
authors.forename: L B
authors.initials: LB
authors.lastname: Duffy
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D002939:Ciprofloxacin / Q000494:pharmacology*; D004917:Erythromycin / Q000494:pharmacology*; D024841:Fluoroquinolones; D006801:Humans; D009177:Mycoplasma pneumoniae / Q000187:drug effects*; D015363:Quinolones
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D015363:Quinolones; D002939:Ciprofloxacin; D004917:Erythromycin; C053091:lomefloxacin