[A biotest for determining human skin contamination by platinoids].
Being toxic, platinum metallic compounds can cause a number of allergic diseases called platinosis. Wide industrial application of these compounds specifies the necessity for developing the technique of platinoid identification on workers' clothes and skin both for preventive purposes and for determination of neglected loss of metals. Compared to the available methods the proposed biotest based on changes in reaction kinetics of bacterial luminescence enables one to raise sensitivity and accuracy of measurements of platinum metals' concentrations. By means of this technique, the sorption effect of platinum compounds on human skin has been demonstrated. General feasibility of using the above method for platinoid identification on skin has been demonstrated. Thus it becomes possible to prevent platinosis development in workers.
Oborina
R I
RI
Kratasiuk
V A
VA
D000497:Alloys / Q000009:adverse effects / Q000032:analysis; D003877:Dermatitis, Contact / Q000175:diagnosis / Q000209:etiology; D009783:Dermatitis, Occupational / Q000139:chemically induced / Q000175:diagnosis; D038181:FMN Reductase; D006801:Humans; D008156:Luciferases; D008163:Luminescent Measurements; D009247:NADH, NADPH Oxidoreductases; D010984:Platinum / Q000009:adverse effects* / Q000032:analysis; D017671:Platinum Compounds; D012867:Skin / Q000187:drug effects*; D012882:Skin Tests / Q000379:methods
D000497:Alloys; D017671:Platinum Compounds; C030173:platinum chloride; D010984:Platinum; D008156:Luciferases; D038181:FMN Reductase; D009247:NADH, NADPH Oxidoreductases
Biotest dlia opredeleniia zagriazneniia kozhi liudeĭ platinoidami.