title: [Genetic factors as determinants of drug response].
abstract: Pharmacogenetics deals with the influence of genetic factors upon the response to drugs. Therapeutic and side effects are affected by pharmacokinetic and pharmacodynamic changes. Classic examples are presented, in particular those concerning mechanisms of oxidation, acetylation and hydrolysis. The impact of this discipline on therapeutics is discussed.
authors.forename: M
authors.initials: M
authors.lastname: Ligueros
authors.forename: H
authors.initials: H
authors.lastname: Saavedra
authors.forename: M
authors.initials: M
authors.lastname: Ligueros
authors.forename: R
authors.initials: R
authors.lastname: Cruz-Coke
mesh_terms: D004358:Drug Therapy; D005819:Genetic Markers; D006801:Humans; D010597:Pharmacogenetics
chemical_list: D005819:Genetic Markers
vernacular_title: Factores genéticos como determinantes de la respuesta a fármacos.