Malignant mixed müllerian tumor of the uterus with neuroectodermal differentiation.
A case of malignant mixed müllerian tumor of the uterus with neuroectodermal differentiation is reported. The most notable feature of the tumor was its large component of central nervous system tissue containing both glial and neuronal elements. The islands of neural tissue were admixed with more conventional carcinomatous and sarcomatous elements typically found in tumors of this type. The neuroectodermal component was conspicuous in the residual uterine tumor removed after radiotherapy, but not in the initial biopsy specimens. The patient died after developing local recurrence and distant metastases, which were treated with chemotherapy.
Gersell
D J
DJ
Department of Pathology, Washington University School of Medicine, St. Louis, Missouri.
Duncan
D A
DA
Fulling
K H
KH
D000368:Aged; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D009373:Neoplasms, Germ Cell and Embryonal / Q000378:metabolism / Q000473:pathology*; D014594:Uterine Neoplasms / Q000378:metabolism / Q000473:pathology*