title: Changes in peripheral hemodynamics after percutaneous transluminal angioplasty.
abstract: We measured ankle/arm pressure indexes and blood flow rates before and after performing percutaneous transluminal angioplasty in 36 extremities. Flow rates through the leg were determined with a magnetic resonance blood flow scanner. All patients had claudication; one had gangrene, another had an ulcer, and two complained of rest pain. The median age was 65 years, and 72% were men. There were 25 dilations of the iliac artery, 12 of the superficial femoral artery, and eight of the popliteal arteries; nine patients had two arterial segments dilated. Nineteen legs had ankle/arm pressure indexes before percutaneous transluminal angioplasty of less than 0.80 (range 0.51 to 0.75); their flow rates averaged 40 +/- 20 (SD) ml/min. After percutaneous transluminal angioplasty flow and pressure increased significantly in 14 of these 19 legs, and three had no hemodynamic improvement; in one leg only pressure and in another only flow increased significantly. The remaining 17 extremities had ankle/arm pressure indexes before percutaneous transluminal angioplasty ranging from 0.81 to 1.09; their flow rates averaged 53 +/- 27 (SD) ml/min. Abnormal flow rates were detected in 15 of these 17 extremities. With near-normal ankle/arm pressure indexes no significant increase in pressure was anticipated. Flow rates augmented to 75 +/- 28 (SD) ml/min after percutaneous transluminal angioplasty; a significant increase in flow was noted in 12 legs (71%). For patients with ankle/arm indexes before percutaneous transluminal angioplasty of less than 0.80, either pressure or flow measurements should corroborate the benefits of the operation, whereas if the ankle arm index is greater than 0.80, flow measurements are most likely to substantiate changes in peripheral hemodynamics.
authors.affiliation: Vascular Laboratory, Saint Joseph Medical Center, Burbank, CA 91505.
authors.forename: S X
authors.initials: SX
authors.lastname: Salles-Cunha
authors.forename: G
authors.initials: G
authors.lastname: Andros
authors.forename: L B
authors.initials: LB
authors.lastname: Dulawa
authors.forename: R W
authors.initials: RW
authors.lastname: Harris
authors.forename: R W
authors.initials: RW
authors.lastname: Oblath
mesh_terms: D000368:Aged; D000800:Angioplasty, Balloon; D001783:Blood Flow Velocity; D001794:Blood Pressure; D005260:Female; D005734:Gangrene / Q000628:therapy; D006439:Hemodynamics; D006801:Humans; D007383:Intermittent Claudication / Q000628:therapy; D007866:Leg / Q000503:physiopathology*; D007871:Leg Ulcer / Q000628:therapy; D008297:Male; D008875:Middle Aged