title: Microbial enzymes for oxidation of organic molecules.
abstract: Enzymatic systems employed by microorganisms for oxidative transformation of various organic molecules include laccases, ligninases, tyrosinases, monooxygenases, and dioxygenases. Reactions performed by these enzymes play a significant role in maintaining the global carbon cycle through either transformation or complete mineralization of organic molecules. Additionally, oxidative enzymes are instrumental in modification or degradation of the ever-increasing man-made chemicals constantly released into our environment. Due to their inherent stereo- and regioselectivity and high efficiency, oxidative enzymes have attracted attention as potential biocatalysts for various biotechnological processes. Successful commercial application of these enzymes will be possible through employing new methodologies, such as use of organic solvents in the reaction mixtures, immobilization of either the intact microorganisms or isolated enzyme preparations on various supports, and genetic engineering technology.
authors.affiliation: Central Research and Development Department, E.I. Du Pont de Nemours and Company, Wilmington, Delaware.
authors.forename: F S
authors.initials: FS
authors.lastname: Sariaslani
mesh_terms: D001419:Bacteria / Q000201:enzymology*; D001709:Biotechnology; D002625:Chemistry, Organic; D004798:Enzymes / Q000378:metabolism*; D005658:Fungi / Q000201:enzymology*; D042845:Laccase; D014442:Monophenol Monooxygenase / Q000378:metabolism; D055601:Organic Chemistry Phenomena; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000378:metabolism; D010105:Oxygenases / Q000378:metabolism
chemical_list: D004798:Enzymes; D010088:Oxidoreductases; D042845:Laccase; D010105:Oxygenases; D014442:Monophenol Monooxygenase; C044391:ligninase