title: Pulsed Doppler assessment of left ventricular diastolic filling in children with left ventricular outflow obstruction before and after balloon angioplasty.
abstract: To assess left ventricular (LV) diastolic filling in children with pressure overload hypertrophy, 12 patients with LV outflow obstruction (7 with aortic valve stenosis and 5 with aortic coarctation) and 12 healthy, age-matched control subjects were examined. Each child underwent M-mode echocardiography and pulsed Doppler examination of the LV inflow. The patients with LV outflow obstruction had cardiac catheterization and balloon angioplasty. Their echo/Doppler examinations were performed in the catheterization laboratory before and immediately after balloon angioplasty. From the M-mode echocardiogram, the LV cavity dimensions and wall thicknesses, LV mass and shortening fraction were measured. The following measurements were made from the Doppler recording: peak velocities at rapid ventricular filling (peak E) and during atrial contraction (peak A), ratio of peak E to peak A velocities, total area under the Doppler curve, percent of the total Doppler area occurring in the first one-third of diastole (0.33 area fraction), percent of the total area occurring under the E wave (E area fraction), percent of the total area occurring under the A wave (A area fraction) and the ratio of E area to A area.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Pediatrics, C.S. Mott Children's Hospital, University of Michigan Medical Center, Ann Arbor 48109.
authors.forename: J N
authors.initials: JN
authors.lastname: Meliones
authors.forename: A R
authors.initials: AR
authors.lastname: Snider
authors.forename: G A
authors.initials: GA
authors.lastname: Serwer
authors.forename: E M
authors.initials: EM
authors.lastname: Shaffer
authors.forename: A P
authors.initials: AP
authors.lastname: Rocchini
authors.forename: R H
authors.initials: RH
authors.lastname: Beekman
authors.forename: A
authors.initials: A
authors.lastname: Rosenthal
authors.forename: M
authors.initials: M
authors.lastname: Dick
authors.forename: J
authors.initials: J
authors.lastname: Peters
authors.forename: P
authors.initials: P
authors.lastname: Reynolds
mesh_terms: D000293:Adolescent; D000800:Angioplasty, Balloon; D002648:Child; D002675:Child, Preschool; D015150:Echocardiography, Doppler; D005260:Female; D006352:Heart Ventricles / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008297:Male; D009200:Myocardial Contraction; D014694:Ventricular Outflow Obstruction / Q000503:physiopathology* / Q000628:therapy