Is breast-milk epidermal growth factor biologically active in the suckling?
Milk-borne epidermal growth factor (EGF) survives in the gastrointestinal tract and is delivered in active form to peripheral organs. The dose dependence of EGF effects in sucklings needs to be clarified, as do possible interactions with other biologically active peptides in milk.
Koldovský
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Department of Pediatrics, Children's Research Center, University of Arizona College of Medicine, Tucson 85724.
D000818:Animals; D000833:Animals, Suckling; D004064:Digestive System / Q000187:drug effects / Q000378:metabolism; D004815:Epidermal Growth Factor / Q000008:administration & dosage / Q000378:metabolism*; D006801:Humans; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D008895:Milk, Human / Q000378:metabolism*
D004815:Epidermal Growth Factor