title: A method for the analysis of lithium in liquid droplets using isotopic dilution and SIMS measurements.
abstract: An absolute, fairly rapid method for the analysis of lithium in liquid droplets is described. It is based on the isotopic dilution of a 6Li (or 7Li)-enriched lithium salt, and on the measurement of isotopic ratios using Secondary Ion Mass Spectrometry. The sensitivity is well adapted to the analysis of lithium in minute volumes of plasma taken from patients suffering from manic-depressive psychosis.
authors.affiliation: Laboratorie Echanges cellulaires, UA CNRS 203, Faculté des Sciences, Mont-Saint-Aignan, France.
authors.forename: M
authors.initials: M
authors.lastname: Thellier
authors.forename: C
authors.initials: C
authors.lastname: Heurteaux
authors.forename: P
authors.initials: P
authors.lastname: Galle
authors.forename: F
authors.initials: F
authors.lastname: Jouen
authors.forename: L
authors.initials: L
authors.lastname: Colonna
authors.forename: J C
authors.initials: JC
authors.lastname: Wissocq
mesh_terms: D007554:Isotopes; D008094:Lithium / Q000097:blood*; D013058:Mass Spectrometry / Q000379:methods; D011865:Radioisotope Dilution Technique
chemical_list: D007554:Isotopes; D008094:Lithium