[Effects of acute loading of alcohol on platelet aggregation in normal subjects].
Ten healthy subjects were submitted to alcohol loading (0.8 g/kg body weight; average alcohol blood level 0.97 g 0/00). The number of platelets, hematocrit and ADP-induced platelet aggregation curves did not show any variation from baseline. Significant changes (p less than 0.05) were observed as regards latent period (increased) and maximum amplitude (reduced) for collagen-induced platelet aggregation. In agreement with others, the authors conclude that alcohol definitely inhibits platelet aggregation.
Galante
A
A
Lenci
R
R
Pierangeli
L
L
Filice
A
A
Calcagnini
G
G
Chessa
C
C
D000328:Adult; D000431:Ethanol / Q000097:blood / Q000494:pharmacology*; D006400:Hematocrit; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology*; D010976:Platelet Count
D010975:Platelet Aggregation Inhibitors; D000431:Ethanol
Effetto del carico acuto di alcool sull'aggregazione piastrinica in soggetti normali.