title: Low dose sufentanil for major intracranial surgery.
abstract: The use of intravenous sufentanil in a single dose of 3 to 5 micrograms/kg body weight, was evaluated in 41 patients anesthetised for major intracranial surgery. It was assessed in a technique of balanced anesthesia which allowed controllable alteration in cardiovascular parameters and rapid postoperative recovery and neurological evaluation. It was concluded that the 4 micrograms/kg dose was superior regarding peroperative stability and recovery. The delayed recovery in aneurysm and fossa posterior surgery should be explained by several factors not involving the anesthetic technique.
authors.affiliation: Department of Anesthesiology, University of Antwerp, Belgium.
authors.forename: L
authors.initials: L
authors.lastname: Janssen
authors.forename: M
authors.initials: M
authors.lastname: Vercauteren
authors.forename: G
authors.initials: G
authors.lastname: Hanegreefs
authors.forename: H
authors.initials: H
authors.lastname: Noorduin
mesh_terms: D000328:Adult; D000368:Aged; D000762:Anesthesia Recovery Period; D000769:Anesthesia, Inhalation; D000771:Anesthesia, Intravenous; D000777:Anesthetics / Q000008:administration & dosage*; D001927:Brain Diseases / Q000601:surgery*; D004305:Dose-Response Relationship, Drug; D005283:Fentanyl / Q000008:administration & dosage / Q000031:analogs & derivatives*; D006801:Humans; D007023:Hypotension, Controlled; D008875:Middle Aged; D017409:Sufentanil
chemical_list: D000777:Anesthetics; D017409:Sufentanil; D005283:Fentanyl