[The effect of the inhalation of a single atrovent dose on pulmonary ventilation function and respiratory mechanics in patients with chronic obstructive bronchitis].
A study was made of the action of inhalation of a single atrovent dose in 20 patients with chronic obstructive bronchitis. All the patients demonstrated a considerable abatement or disappearance of dyspnea, and a reduction of the number of dry rales. The vital capacity of the lungs, the volume of forced expiration, maximal pulmonary ventilation, MOCmax, MOC50, and MOC75 substantially increased. The respiratory work diminished on the average by 32.3% primarily due to the lessening of non-elastic lung resistance. The rise of pulmonary static extensibility and reduction of pulmonary elastic propulsion were recorded. In patients with and without clinical signs of bronchospasm, the action of atrovent was identical.
Tetenev
F F
FF
Cherniavskaia
G M
GM
D000280:Administration, Inhalation; D000328:Adult; D001286:Atropine Derivatives / Q000008:administration & dosage*; D001991:Bronchitis / Q000188:drug therapy* / Q000503:physiopathology; D002908:Chronic Disease; D004341:Drug Evaluation; D006801:Humans; D009241:Ipratropium / Q000008:administration & dosage*; D008875:Middle Aged; D012129:Respiratory Function Tests; D015656:Respiratory Mechanics / Q000187:drug effects* / Q000502:physiology; D013997:Time Factors; D014692:Ventilation-Perfusion Ratio / Q000187:drug effects* / Q000502:physiology
D001286:Atropine Derivatives; D009241:Ipratropium
Vliianie ingaliatsii razovoĭ dozy atroventa na ventiliatsionnuiu funktsiiu legkikh i mekhaniku dykhaniia u bol'nykh khronicheskim obstruktivnym bronkhitom.