Responses of myocardial blood flows to whole-body vibration in the dog.
Experimentally acute exposure to whole-body vibration resulted in changes in myocardial blood flows in the in vivo dog. Regional myocardial blood flows measured by a hydrogen gas clearance method were increased at a vibration frequency of 120 Hz and decreased at 50 Hz. No appreciable changes were found in presence of a beta-adrenergic blocker. The values of plasma cyclic nucleotides were increased at both frequencies of vibration, more at 50 Hz than at 120 Hz. No significant changes were observed in heart rates and arterial pressure during and after vibration load. These findings suggest that increased myocardial blood flows in response to vibration may be related more to the frequency of vibration than to beta-adrenergic actions.
Matoba
T
T
Department of Environmental Medicine, Kurume University School of Medicine, Japan.
Chiba
M
M
D000818:Animals; D001794:Blood Pressure; D003326:Coronary Circulation / Q000187:drug effects; D000242:Cyclic AMP / Q000097:blood; D006152:Cyclic GMP / Q000097:blood; D004285:Dogs; D006339:Heart Rate; D011433:Propranolol / Q000494:pharmacology; D014732:Vibration
D011433:Propranolol; D000242:Cyclic AMP; D006152:Cyclic GMP