title: [Changes in the etiologic structure of Sonne shigellosis in its multiyear dynamics].
abstract: The dynamics of Sonne dysentery morbidity in connection with changes in the structure of S. sonnei circulating among the population of Leningrad for the period of 1959-1984 was studied. Considering such sign as the leading fermentovar, three smaller periods were established in this stretch of time. Changes in the structure of circulating shigellae were accompanied by changes in the intensity and direction of tendencies or decrease in the manifest and asymptomatic forms of infection, as well as in annual morbidity levels and seasonal rises. A slow decrease in morbidity, which started in 1974, occurs in the presence of the predominant circulation of S. sonnei, fermentovar II, among the population; this fermentovar showed greater virulence and immunogenicity than other biovars. One of the decisive moments characterizing the dynamics of the epidemic process of Sonne dysentery is the intensity of the circulation of shigellae in the S-form, and the intensity of the population immunity of the host, linked with this fact, is subject to phasic fluctuations during each annual epidemic cycle.
authors.forename: M I
authors.initials: MI
authors.lastname: Shapiro
authors.forename: N E
authors.initials: NE
authors.lastname: Nechaeva
authors.forename: A A
authors.initials: AA
authors.lastname: Degtiarev
authors.forename: S V
authors.initials: SV
authors.lastname: Filimonov
mesh_terms: D000367:Age Factors; D004405:Dysentery, Bacillary / Q000453:epidemiology / Q000209:etiology* / Q000382:microbiology; D006801:Humans; D012426:Russia / Q000453:epidemiology; D012621:Seasons; D012703:Serotyping; D012764:Shigella sonnei / Q000145:classification / Q000302:isolation & purification; D013997:Time Factors; D014505:Urban Population
vernacular_title: Izmeneniia étiologicheskoĭ struktury shigelleza Zonne v mnogoletneĭ dinamike.