Aromatic tetra-amidines with antiproteolytic activity inhibit platelet aggregation and secretion.
Milani
L
L
Istituto di Chimica Biologica, Università di Ferrara, Italy.
Ferroni
R
R
Zaccarini
M
M
Traniello
S
S
D000244:Adenosine Diphosphate / Q000037:antagonists & inhibitors; D000578:Amidines / Q000494:pharmacology*; D001550:Benzamidines / Q000494:pharmacology; D001792:Blood Platelets / Q000187:drug effects* / Q000378:metabolism; D000001:Calcimycin / Q000037:antagonists & inhibitors; D003094:Collagen / Q000037:antagonists & inhibitors; D003864:Depression, Chemical; D006801:Humans; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology*; D012310:Ristocetin / Q000037:antagonists & inhibitors; D012636:Secretory Rate / Q000187:drug effects; D012701:Serotonin / Q000378:metabolism; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D013917:Thrombin / Q000037:antagonists & inhibitors
D000578:Amidines; D001550:Benzamidines; D010975:Platelet Aggregation Inhibitors; D012310:Ristocetin; D012701:Serotonin; D000001:Calcimycin; D000244:Adenosine Diphosphate; C057885:1,3-di-(4-amidinophenoxy)-2,2-bis-(4-amidinophenoxymethyl)propane; D003094:Collagen; C062503:4,4'-((2,2-bis((4-(aminoiminomethyl)-2-iodophenoxy)methyl)-1,3-propanediyl)bis(oxy))bis(3-iodobenzenecarboximidamide); C057886:4,4'-(2,2-bis((4-(aminoiminomethyl)-2-bromophenoxy)methyl)-1,3-propanediyl)bis(oxy))bis(3-bromobenzenecarboximidamide; D013917:Thrombin; C032157:benzamidine; D013755:Tetradecanoylphorbol Acetate