title: Synovial sarcoma: MR imaging.
abstract: Ten patients with biopsy-proved synovial sarcoma were evaluated by magnetic resonance (MR) imaging on a 1.5-T unit. The lesions showed intermediate signal intensity on T1-weighted images and heterogeneous high signal intensity on T2-weighted images. Tumors were well-demarcated from normal tissues. Additional information included adjacent bone involvement (one case), femoral vein invasion by tumor (one case), and hemorrhage within the tumors (one case). Four patients underwent a repeat MR examination following chemotherapy. This showed a decrease in size and increase in the signal intensity of three tumors on T2-weighted images, proven to be due to necrosis in one. These changes correlated with clinical regression of disease. While MR in synovial sarcoma does not have any specific signal intensity, it proved to be useful in defining the extent of disease and in determining the response to chemotherapy.
authors.affiliation: Department of Diagnostic Radiology, University of Texas, M.D. Anderson Cancer Center, Houston.
authors.forename: H
authors.initials: H
authors.lastname: Mahajan
authors.forename: J G
authors.initials: JG
authors.lastname: Lorigan
authors.forename: A
authors.initials: A
authors.lastname: Shirkhoda
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013584:Sarcoma, Synovial / Q000175:diagnosis*; D012983:Soft Tissue Neoplasms / Q000175:diagnosis*