[Study of thermo-stabilizing effect of tocopherol on rhodopsin in the presence of fatty acids using the method of differential scanning calorimetry].
By the method of differential scanning calorimetry it was shown that the addition of arachidonic acid to photoreceptor membranes is accompanied by concentration-dependent shift of thermograms curve of rhodopsin value. Addition of tocopherol to photoreceptor membranes prevents the turbulent effect of the fatty acid on opsin and rhodopsin. The obtained data are discussed from the point of view of membrane protective properties of tocopherol.
Gotlib
V A
VA
Tiurin
V A
VA
Rychkova
M P
MP
Berman
A L
AL
Lev
A A
AA
Kagan
V E
VE
D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000494:pharmacology; D002152:Calorimetry, Differential Scanning; D005136:Eye Proteins / Q000032:analysis; D005227:Fatty Acids / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D010786:Photoreceptor Cells / Q000187:drug effects*; D012168:Retinal Pigments / Q000032:analysis*; D012243:Rhodopsin / Q000032:analysis*; D017299:Rod Opsins; D013696:Temperature; D014810:Vitamin E / Q000494:pharmacology*
D001095:Arachidonic Acids; D005136:Eye Proteins; D005227:Fatty Acids; D012168:Retinal Pigments; D017299:Rod Opsins; D014810:Vitamin E; D016718:Arachidonic Acid; D012243:Rhodopsin
Izuchenie termostabiliziruiushchego deĭstviia tokoferola na rodopsii v prisutstvii zhirnykh kislot metodom differentsial'noĭ skaniruiushcheĭ kalorimetrii.