title: Synthetic stable orally and transdermally long-acting prostaglandin E2 (PGE2) congener (viprostol; CL 115,347) and prostacyclin congener (CL 115,999) as antihypertensive agents.
authors.affiliation: American Cyanamid Company, Medical Research Division, Lederle Laboratories, Pearl River, New York 10965.
authors.forename: P
authors.initials: P
authors.lastname: Cervoni
authors.forename: P S
authors.initials: PS
authors.lastname: Chan
mesh_terms: D000279:Administration, Cutaneous; D000284:Administration, Oral; D000818:Animals; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects*; D015232:Dinoprostone / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D011464:Epoprostenol / Q000627:therapeutic use / Q000031:analogs & derivatives; D006973:Hypertension / Q000188:drug therapy*; D051381:Rats; D011918:Rats, Inbred SHR
chemical_list: D000959:Antihypertensive Agents; C060228:CL 115999; D011464:Epoprostenol; D015232:Dinoprostone; C034232:viprostol