[Anticarcinogenic action of vitamins PP and B6 in the natulan initiation of malignant growth in mice].
Parenteral administration of vitamins PP and B6 at the initiation stage of natulan-induced carcinogenesis was shown to significantly inhibit formation of lung adenomas. The preventive effect was found to depend on treatment schedule. Biochemical aspects of anticarcinogenic action of the vitamins require special investigation.
Draudin-Krylenko
V A
VA
Bukin
Iu V
IuV
Nikonova
T V
TV
D000236:Adenoma / Q000139:chemically induced / Q000188:drug therapy* / Q000378:metabolism; D000818:Animals; D000970:Antineoplastic Agents; D004353:Drug Evaluation, Preclinical; D004347:Drug Interactions; D005260:Female; D008175:Lung Neoplasms / Q000139:chemically induced / Q000188:drug therapy* / Q000378:metabolism; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009536:Niacinamide / Q000493:pharmacokinetics / Q000627:therapeutic use*; D011344:Procarbazine / Q000493:pharmacokinetics / Q000633:toxicity*; D011736:Pyridoxine / Q000493:pharmacokinetics / Q000627:therapeutic use*; D013997:Time Factors
D000970:Antineoplastic Agents; D009536:Niacinamide; D011344:Procarbazine; D011736:Pyridoxine
Antikantserogennoe deĭstvie vitaminov PP i B6 pri initsiatsii natulanom zlokachestvennogo rosta u mysheĭ.