[Effects of polyunsaturated phosphatidylcholine in alcoholic liver diseases].
The aim of this study is to assess "in vitro" the influence of polyunsaturated phosphatidylcholine on the erythrocyte membrane fluidity in alcoholics (greater than 180 g/die) and control subjects (less than 50 g/die), investigated by the evaluation of fluorescent polarization of DPH. In both groups a significant increase of membrane microviscosity was observed after incubation with 0.04 microM and 0.08 microM of PC compared to baseline values.
Stefanini
G
G
Zunarelli
P
P
Mazzetti
M
M
Biagi
P
P
Bordoni
A
A
Petio
C
C
Amorati
P
P
Hrelia
S
S
Gasbarrini
G
G
Turchetto
E
E
D000328:Adult; D000368:Aged; D001809:Blood Viscosity / Q000187:drug effects; D004910:Erythrocyte Membrane / Q000187:drug effects; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008108:Liver Diseases, Alcoholic / Q000097:blood / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010713:Phosphatidylcholines / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*
D010713:Phosphatidylcholines; C029449:polyene phosphatidylcholine
Effetti della fosfatidilcolina polinsatura nelle epatopatie alcoliche.