Regulation of IgE biosynthesis.
A biologic cell product that in an experimental system completely and and specifically suppresses the IgE response! This is one of the intriguing findings that give rise to optimism that the growing understanding of mechanisms that regulate normal IgE responses will, in the not-too-distant future, provide rational and effective therapy for the prevention and management of atopic diseases.
Ishizaka
K
K
Johns Hopkins University School of Medicine, Baltimore.
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology; D002454:Cell Differentiation; D006801:Humans; D007127:Immunoglobulin Constant Regions / Q000276:immunology; D007073:Immunoglobulin E / Q000096:biosynthesis* / Q000235:genetics; D007132:Immunoglobulin Isotypes / Q000096:biosynthesis; D015847:Interleukin-4; D007378:Interleukins / Q000276:immunology; D008222:Lymphokines / Q000096:biosynthesis; D051379:Mice; D008815:Mice, Inbred Strains / Q000276:immunology; D029584:Prostatic Secretory Proteins; D051381:Rats; D013491:Suppressor Factors, Immunologic / Q000096:biosynthesis; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology
D007127:Immunoglobulin Constant Regions; D007132:Immunoglobulin Isotypes; D007378:Interleukins; D008222:Lymphokines; D029584:Prostatic Secretory Proteins; D013491:Suppressor Factors, Immunologic; C043076:beta-microseminoprotein; C013059:immunoglobulin-binding factors; D015847:Interleukin-4; D007073:Immunoglobulin E