title: [Dynamics of metastasis of breast cancer to the bones].
abstract: A total of 120 cases with Stages I (n = 32) and IIa (n = 88) mammary carcinoma who later developed metastases to the bones are analyzed. The authors come to a conclusion that the time course of the metastases development directly depends on the tumor process stage. Postoperative thiophosphamide chemotherapy is the most effective method for the prevention of metastases to the bones; postoperative radiotherapy is conducive to a most rapid dissemination of the metastases in the bones.
authors.forename: T O
authors.initials: TO
authors.lastname: Kutateladze
authors.forename: I B
authors.initials: IB
authors.lastname: Moroshkin
authors.forename: S M
authors.initials: SM
authors.lastname: Portnoĭ
mesh_terms: D001859:Bone Neoplasms / Q000209:etiology / Q000517:prevention & control / Q000556:secondary*; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D015409:Mastectomy, Radical; D009367:Neoplasm Staging; D011182:Postoperative Care; D011878:Radiotherapy / Q000009:adverse effects; D013852:Thiotepa / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D013852:Thiotepa
vernacular_title: Dinamika metastazirovaniia raka molochnoĭ zhelezy v kostiakh.