The human endonexin II (ENX2) gene is located at 4q28----q32.
A relatively recently identified family of structurally similar Ca2(+)-dependent phospholipid binding proteins is called the annexin gene family. At least seven genes are known, although their exact functions are unclear. The endonexin II gene (ENX2), one member of the gene family, is assigned to 4q28----q32 using both Southern transfer analysis of human x rodent somatic cell hybrid DNAs and in situ chromosome hybridization. One of the lipocortin II genes, another annexin, had previously been assigned to the long arm of chromosome 4.
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Biological Carcinogenesis and Development Program, Program Resources Inc., NCI-Frederick Cancer Research Facility, MD 21701.
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Jaye
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Haigler
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Kaplan
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O'Brien
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D000818:Animals; D017304:Annexin A5; D002135:Calcium-Binding Proteins / Q000235:genetics*; D002642:Chick Embryo; D002874:Chromosome Mapping; D002894:Chromosomes, Human, Pair 4 / Q000032:analysis / Q000648:ultrastructure*; D006224:Cricetinae; D003412:Cricetulus; D004247:DNA / Q000032:analysis / Q000235:genetics; D005796:Genes / Q000235:genetics*; D006801:Humans; D006822:Hybrid Cells / Q000648:ultrastructure; D051379:Mice; D009693:Nucleic Acid Hybridization
D017304:Annexin A5; D002135:Calcium-Binding Proteins; D004247:DNA