Right ventricular dysplasia: angiographic study.
At the moment, the most reliable method for diagnosing right ventricular dysplasia is considered to be angiography. Morphological alterations such as the presence of akinetic/dyskinetic areas, aneurysmatic dilatations and deep anteroapical fissuring, not necessarily associated with an increase in ventricular volume, are understood to be angiographic criteria indicating dysplasia. To verify their diagnostic value, these abnormalities have been evaluated in: (1) 33 patients suspected of having dysplasia because of PVBs with LBBB morphology and with 'borderline' involvement of the right ventricle or without instrumental evidence of cardiac disease (Group A); (2) 16 subjects with no arrhythmia and normal left ventricular angiography, coronary and bioptic findings (Group B); (3) 36 patients with a clinical, angiographic and bioptic diagnosis of dilated idiopathic cardiomyopathy (Group C). In 48.5% of the patients in Group A, angiography showed localized akinesia/dyskinesia (12 patients), small conical outpouchings persisting during systole (10 patients) and apical deep fissuring (two patients). In 81% of these patients, endomyocardial biopsy showed the presence of fibrous and/or adipose tissue in at least 20% of the examined sample. Angiographic abnormalities suggesting dysplasia were found in none of the normal subjects and only in two of the 36 patients with dilated cardiomyopathy (5.5%).
Chiddo
A
A
Division of Cardiology, University of Bari, Italy.
Locuratolo
N
N
Gaglione
A
A
Bortone
A
A
Troito
G
G
Musci
S
S
Grimaldi
N
N
Rizzon
P
P
D000293:Adolescent; D000328:Adult; D000787:Angina Pectoris / Q000000981:diagnostic imaging; D000792:Angiography; D006332:Cardiomegaly / Q000000981:diagnostic imaging; D009202:Cardiomyopathies / Q000175:diagnosis* / Q000503:physiopathology; D002311:Cardiomyopathy, Dilated / Q000000981:diagnostic imaging; D002932:Cineangiography; D017023:Coronary Angiography; D003937:Diagnosis, Differential; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged