[Iterative surgery in germ cell tumor].
Between 1979 and 1988, iterative surgery was performed on 13 patients for a germ-cell tumor. Apart from orchidectomy, surgery was not the first modality of treatment. On the other hand, 21 surgical procedures were performed for residual tumoral masses after chemotherapy or recurrences. In one third of the cases, only necrosis of fibrosis was resected. Out of 13 patients, 7 died of tumor; 6 are alive (3 with complete remission). Surgery is always indicated in stage IIA to IV nonseminomatous tumors in case of residual tumoral deposits after chemotherapy. For seminoma, surgery is carried out only for retroperitoneal residues larger than 3 cm in diameter. Surgery is also indicated for persistent pulmonary or mediastinal metastases following chemotherapy. Complete surgical excision of residual masses may be technically difficult but is of prime importance as combined chemotherapy and surgery doubles the complete remission rate in comparison to chemotherapy alone.
Merlini
M
M
Boumghar
M
M
Berner
M
M
Leyvraz
S
S
Chapuis
G
G
D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000601:surgery*; D009373:Neoplasms, Germ Cell and Embryonal / Q000601:surgery*; D012186:Retroperitoneal Neoplasms / Q000601:surgery*; D013736:Testicular Neoplasms / Q000601:surgery*
Chirurgie itérative en cas de tumeur germinale.