[Molecular mechanisms of cellular adhesion].
Regeneration of connective tissue structures lost as a result of periodontal disease remains the major goal of periodontal therapy. The ability of cells of the periodontium to adhere to the tooth surface is central to a number of phenomenons. Among these are cellular migration, morphogenesis and wound healing. Several classes of molecules appear to mediate the ability of cells to adhere. These cells utilize a group of receptors called Integrins to anchor themselves to the extra-cellular matrix. The receptors are transmembrane heterodimers which serve as bridges which communicate informations between the extra-cellular matrix and the cytoskeleton.
Sautier
J M
JM
D002448:Cell Adhesion / Q000502:physiology*; D015815:Cell Adhesion Molecules / Q000502:physiology*; D003598:Cytoskeletal Proteins / Q000502:physiology*; D003599:Cytoskeleton; D004846:Epithelial Attachment / Q000166:cytology*; D005109:Extracellular Matrix / Q000166:cytology; D006801:Humans; D016023:Integrins; D010519:Periodontium / Q000166:cytology*; D016596:Vinculin; D014945:Wound Healing / Q000502:physiology
D015815:Cell Adhesion Molecules; D003598:Cytoskeletal Proteins; D016023:Integrins; D016596:Vinculin
Mécanismes moléculaires de l'adhésion cellulaire.