title: [Evaluation of biological equivalency of Sustonit (Polfa) and Sustac by plethysmography].
abstract: Bioequivalence of Sustonit tablets (2.6 and 6.5 mg) produced at WZF Polfa and Sustac tablets (2.6 and 6.5 mg) made by Krka (Yugoslavia) and WZF Polfa (Poland) was studied by means of the digital plethysmography. All the three drugs with the nitroglycerin content of 2.6 mg were found to be biologically equivalent. On the other hand, Sustonit (WZF Polfa) and Sustac (Krka) tablets with 6.5 mg nitroglycerin proved to possess better bioavailability than Sustac (6.5 mg) tablets produced previously at WZF Polfa.
authors.forename: M
authors.initials: M
authors.lastname: Filczewski
authors.forename: Z
authors.initials: Z
authors.lastname: Sadowski
authors.forename: M
authors.initials: M
authors.lastname: Kobylińska
mesh_terms: D000328:Adult; D003692:Delayed-Action Preparations; D004353:Drug Evaluation, Preclinical; D005385:Fingers / Q000098:blood supply*; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D005996:Nitroglycerin / Q000008:administration & dosage / Q000493:pharmacokinetics*; D010992:Plethysmography, Impedance / Q000379:methods; D011044:Poland; D013608:Tablets, Enteric-Coated; D015022:Yugoslavia
chemical_list: D003692:Delayed-Action Preparations; D013608:Tablets, Enteric-Coated; D005996:Nitroglycerin
vernacular_title: Ocena biorównowazności preparatów sustonit polfa z preparatami sustac przy uzyciu metody pletysmograficznej.