Prognostic significance of selected histochemical and immunohistochemical markers in breast cancer.
The bioptic materials from patients with breast carcinoma operated in the period of 1976 to 1977 were studied for expression of binding sites for monoclonal antibodies HMFG.06 (detecting mucine-like molecules of membranes of milk fat globules) and 2FD4 (detecting the protein epitope of CEA), and for lectin Con A (detecting free residua of alpha-D-mannose). The results obtained were compared with survival rate of patients and with histological type of carcinoma. The interpretation of the results can help to specify the prognostic validity of histopathological diagnosis.
Petrková
J
J
Kolár
Z
Z
D014408:Biomarkers, Tumor; D001943:Breast Neoplasms / Q000235:genetics / Q000276:immunology*; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007120:Immunochemistry; D037102:Lectins; D011379:Prognosis
D014408:Biomarkers, Tumor; D037102:Lectins