[Bacterial infections in cancer patients without neutropenia. Comparison between 2 antibiotic combinations (aztreonam and oxacillin versus cefoxitin and tobramycin)].
In the treatment of infections arisen in neoplastic patients without neutropenia, 2 antibiotic combinations (aztreonam + oxacillin vs tobramycin + cefoxitin), have been compared with regard to therapeutic effectiveness and tolerability. Twenty patients (age: 30-75) have been studied. Tolerability of both combinations was excellent. Results of this study showed a lower percentage of superinfections and a higher percentage of cure in patients treated with the combination aztreonam + oxacillin, even if the data were not statistically significant.
Apice
G
G
Beneduce
G
G
Bruni
G S
GS
D'Aprile
M
M
Perna
M
M
Silvestro
P
P
Villari
P
P
Pergola
M
M
D000328:Adult; D000368:Aged; D001398:Aztreonam / Q000008:administration & dosage / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000150:complications / Q000188:drug therapy*; D002440:Cefoxitin / Q000008:administration & dosage / Q000627:therapeutic use*; D004341:Drug Evaluation; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications*; D010068:Oxacillin / Q000008:administration & dosage / Q000627:therapeutic use*; D014031:Tobramycin / Q000008:administration & dosage / Q000627:therapeutic use*
D002440:Cefoxitin; D001398:Aztreonam; D010068:Oxacillin; D014031:Tobramycin
Infezioni batteriche in pazienti neoplastici non neutropenici. Confronto tra due associazioni di antibiotici (aztreonam + oxacillina versus cefoxitina + tobramicina).