[In vitro study of platelet preservation during 5 days in reduced-thickness bags].
An in vitro study of platelet concentrates storage for 5 days was performed in PVC bags. Modification of the original three-day containers were introduced by thickness reduction. The results at fifth day were comparable to those at third day in standard plastic bags. During storage, variations of platelet counts were very slight with a low LDH release. PH was stable with a good maintenance of phase microscope platelet morphology. PCO2 and PO2 measurements showed a satisfactory gas permeability which could explain a limited lactate production. If in vivo studies of transfusion recovery confirm these data, platelet concentrates storage could be extended up to 5 days by such modifications of standard three-day PVC bags.
Domenech
J
J
Centre Régional de Transfusion Sanguine de Tøurs.
Babault
C
C
Desbois
I
I
Degenne
M
M
Binet
C
C
Garnier
C
C
Chassaigne
M
M
D001792:Blood Platelets / Q000032:analysis; D001793:Blood Preservation / Q000295:instrumentation*; D002245:Carbon Dioxide / Q000097:blood; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007770:L-Lactate Dehydrogenase / Q000097:blood; D007773:Lactates / Q000096:biosynthesis; D019344:Lactic Acid; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D010974:Platelet Aggregation; D011143:Polyvinyl Chloride; D001620:beta-Thromboglobulin / Q000032:analysis
D007773:Lactates; D001620:beta-Thromboglobulin; D002245:Carbon Dioxide; D019344:Lactic Acid; D011143:Polyvinyl Chloride; D007770:L-Lactate Dehydrogenase; D010100:Oxygen
Etude in vitro de la conservation de plaquettes pendant 5 jours dans des poches d'épaisseur réduite.