Quinone derivatives: synthesis and structure-activity relations of a novel class of eicosanoid antagonists, AA-2414 and its analogs.
Terao
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Chemistry Laboratories, Takeda Chemical Industries, Ltd., Osaka, Japan.
D000818:Animals; D001011:Aorta / Q000502:physiology; D016227:Benzoquinones; D006168:Guinea Pigs; D006538:Heptanoic Acids; D066298:In Vitro Techniques; D007536:Isomerism; D008168:Lung / Q000187:drug effects / Q000502:physiology; D009119:Muscle Contraction / Q000187:drug effects; D011453:Prostaglandins / Q000494:pharmacology*; D011809:Quinones / Q000138:chemical synthesis* / Q000494:pharmacology; D011817:Rabbits; D013189:SRS-A / Q000494:pharmacology; D013329:Structure-Activity Relationship; D014661:Vasoconstriction / Q000187:drug effects
D016227:Benzoquinones; D006538:Heptanoic Acids; D011453:Prostaglandins; D011809:Quinones; D013189:SRS-A; C060230:seratrodast