title: Mapping the mutation causing the X-linked lymphoproliferative syndrome in relation to restriction fragment length polymorphisms on Xq.
abstract: The X-linked lymphoproliferative syndrome (XLP) results in fatal infectious mononucleosis, hypogamma-globulinemia, and malignant lymphoma. The mutation has been mapped relative to several restriction fragment length polymorphism (RFLP) markers in the Xq21-Xq27 vicinity. The DXS37 locus was found to be near both the DXS42 and XLP loci.
authors.affiliation: Department of Pediatrics, Boston University School of Medicine, MA 02118.
authors.forename: J C
authors.initials: JC
authors.lastname: Skare
authors.forename: J L
authors.initials: JL
authors.lastname: Sullivan
authors.forename: A
authors.initials: A
authors.lastname: Milunsky
mesh_terms: D002874:Chromosome Mapping; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000235:genetics*; D008297:Male; D009154:Mutation; D010375:Pedigree; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D011995:Recombination, Genetic; D013577:Syndrome; D014960:X Chromosome