[Therapy of insomnia].
The authors review the neurochemical and electrophysiological features of insomnia, together with the results obtained by various substances. The literature data show that the benzodiazepines (BZ) should be administered for short periods of time, in order to avoid addiction and withdrawal symptoms. For this reason, the authors suggest that, before starting a therapy with such substances, an accurate clinical evaluation should be made and a good knowledge of the pharmacokinetics of the various BZ is essential.
Piccinin
G L
GL
Piccirilli
M
M
Finali
G
G
Stefano
E
E
Poli
R
R
D014151:Anti-Anxiety Agents / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001569:Benzodiazepines; D001921:Brain / Q000378:metabolism; D002395:Catecholamines / Q000378:metabolism; D006801:Humans; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy* / Q000209:etiology / Q000378:metabolism
D014151:Anti-Anxiety Agents; D002395:Catecholamines; D001569:Benzodiazepines
La terapia dell'insonnia.