title: Drugs from emasculated hormones: the principle of syntopic antagonism.
abstract: This lecture outlines the early stages in the discovery of adrenaline beta-receptor antagonists and of the histamine H2-receptor antagonists. It ends with a brief personal view about future research.
authors.affiliation: Kings's College School of Medicine & Dentistry, Department of Analytical Pharmacology, Rayne Institute, London.
authors.forename: J
authors.initials: J
authors.lastname: Black
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000818:Animals; D006635:Histamine H2 Antagonists / Q000494:pharmacology*; D006801:Humans; D011943:Receptors, Adrenergic, beta / Q000187:drug effects; D011970:Receptors, Histamine H2 / Q000187:drug effects; D013329:Structure-Activity Relationship
chemical_list: D000319:Adrenergic beta-Antagonists; D006635:Histamine H2 Antagonists; D011943:Receptors, Adrenergic, beta; D011970:Receptors, Histamine H2