[Urinary enzymes: early biochemical indicators in the biological monitoring study of subjects exposed to styrene].
This paper studies the urinary enzymes N-acetyl-beta-glucosaminidase (NAG) and alanine aminopeptidase (AAP) in workers exposed to styrene. It is possible to consider these enzymes as early biochemical indicators of renal damage, owing to their ability to show alterations in the renal tubule when the creatinine clearance is still in the normal range. This preliminary study shows an increase in the two enzymes in workers exposed to styrene.
Malaguti Aliberti
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Istituto Superiore di Sanità, Roma, Laboratorio di Biochimica Clinica.
Severini
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GC
D000118:Acetylglucosaminidase / Q000652:urine*; D000328:Adult; D000626:Aminopeptidases / Q000652:urine*; D018826:CD13 Antigens; D004796:Clinical Enzyme Tests / Q000379:methods*; D006596:Hexosaminidases / Q000652:urine*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007558:Italy; D007668:Kidney / Q000187:drug effects; D007674:Kidney Diseases / Q000139:chemically induced / Q000175:diagnosis*; D008297:Male; D008991:Monitoring, Physiologic / Q000379:methods; D009784:Occupational Diseases / Q000139:chemically induced / Q000175:diagnosis*; D012767:Ships; D020058:Styrene; D013343:Styrenes / Q000009:adverse effects*; D013997:Time Factors
D013343:Styrenes; D020058:Styrene; D006596:Hexosaminidases; D000118:Acetylglucosaminidase; D000626:Aminopeptidases; D018826:CD13 Antigens
Gli enzimi urinari: indicatori biochimici precoci nello studio del monitoraggio biologico in soggetti esposti a stirene.