title: Multiple versus single antipsychotic drug treatment in chronic psychosis.
abstract: Fourteen patients receiving multiple antipsychotic drugs in a state mental hospital long-term unit comprised the study sample. They completed a 1-year clinical trial to reduce such drugs to a single antipsychotic agent. Six of the 14 patients were successfully converted to a single antipsychotic drug without clinical deterioration. Eight patients showed marked psychiatric decompensation when converted to single antipsychotic therapy. Factors that may have contributed to this difference are discussed.
authors.affiliation: Western State Hospital, Department of Mental Health and Mental Retardation, Commonwealth of Virginia, Stauton 24401.
authors.forename: L S
authors.initials: LS
authors.lastname: Godleski
authors.forename: R
authors.initials: R
authors.lastname: Kerler
authors.forename: J W
authors.initials: JW
authors.lastname: Barber
authors.forename: J L
authors.initials: JL
authors.lastname: Glick
authors.forename: E
authors.initials: E
authors.lastname: Kellogg
authors.forename: W V
authors.initials: WV
authors.lastname: Vieweg
authors.forename: G R
authors.initials: GR
authors.lastname: Yank
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D002908:Chronic Disease; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D011618:Psychotic Disorders / Q000188:drug therapy* / Q000523:psychology
chemical_list: D014150:Antipsychotic Agents