[An immunohistological study of monoclonal antibody BG6 against human breast cancer].
Paraffin sections from a series of human tissues were examined by an indirect immunoperoxidase method with BG6 antibody. Data showed that primary breast cancer (96%) or lymph nodes with metastatic tumors (94%) gave positive result with BG6 antibody. Weak staining was observed in some sections of nonbreast tumors and no evidence of positive immunoperoxidase staining was obtained in benign breast hyperplasia, normal tissues and embryonic tissues examined. It is considered that McAb BG6 might be used as a specific marker for breast cancer.
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D000911:Antibodies, Monoclonal / Q000032:analysis*; D000912:Antibodies, Neoplasm / Q000032:analysis; D014408:Biomarkers, Tumor; D001943:Breast Neoplasms / Q000276:immunology* / Q000473:pathology; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000276:immunology* / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008207:Lymphatic Metastasis
D000911:Antibodies, Monoclonal; D000912:Antibodies, Neoplasm; D014408:Biomarkers, Tumor