title: Topical salicylate therapy (4-ASA and 5-ASA enemas).
abstract: Topical therapy with amino salicylate enemas is the treatment of choice for proctitis, proctosigmoiditis, and left-sided ulcerative colitis. Adjunctive sulfasalazine therapy is often required. Relapse rates of 80 per cent can be expected within 3 months of discontinuing therapy.
authors.affiliation: George Washington University School of Medicine, Washington, DC.
authors.forename: A L
authors.initials: AL
authors.lastname: Ginsberg
mesh_terms: D000287:Administration, Topical; D010131:Aminosalicylic Acid / Q000008:administration & dosage* / Q000627:therapeutic use; D000636:Aminosalicylic Acids / Q000008:administration & dosage* / Q000627:therapeutic use; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D003424:Crohn Disease / Q000188:drug therapy*; D004733:Enema; D006801:Humans; D019804:Mesalamine; D012460:Sulfasalazine / Q000627:therapeutic use
chemical_list: D000636:Aminosalicylic Acids; D012460:Sulfasalazine; D019804:Mesalamine; D010131:Aminosalicylic Acid