Technetium metabolism by lactating goats.
The goat milk transfer coefficients of 99mTc, 95mTc and 99Tc, administered as pertechnetate (TcO4-), were 1.5 x 10(-4), 8.5 x 10(-4) and 1.1 x 10(-2) d L-1, respectively. The differences between the goat milk transfer coefficients of the three Tc isotopes administered as TcO4- were significant (p less than 0.05). The milk transfer coefficients of Tc were affected by chemical form and specific activity. Reduced 99mTc produced a transfer coefficient 17 times lower than that of 99TcO4- in the same goats. Reduction of pertechnetate in the rumen was evaluated to explain the low and variable transfer coefficients.
Ennis
M E
ME
Department of Radiology and Radiation Biology, Colorado State University, Fort Collins 80523.
Johnson
J E
JE
Ward
G M
GM
Boamah
K N
KN
D000284:Administration, Oral; D000818:Animals; D005260:Female; D006041:Goats / Q000378:metabolism*; D007275:Injections, Intravenous; D007774:Lactation; D008892:Milk / Q000032:analysis*; D011247:Pregnancy; D012417:Rumen / Q000032:analysis; D013670:Sodium Pertechnetate Tc 99m / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*
D013670:Sodium Pertechnetate Tc 99m