title: Polyarteritis nodosa and necrotizing glomerulonephritis associated with long-standing silicosis.
abstract: A 55-year-old white male, with silicosis diagnosed 10 years earlier, presented massive proteinuria with microscopic hematuria, moderate renal failure and distal polyneuropathy. Bilateral renal angiography showed multiple intraparenchymal saccular aneurysms. Renal biopsy disclosed a focal segmental necrotizing glomerulonephritis and arteriolitis. After combined corticosteroid and immunosuppressive treatment, renal function improved and remained stable 6 months later.
authors.affiliation: Department of Medicine, La Paz Hospital, Autonomous Faculty of Medicine, Madrid, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Arnalich
authors.forename: C
authors.initials: C
authors.lastname: Lahoz
authors.forename: M L
authors.initials: ML
authors.lastname: Picazo
authors.forename: A
authors.initials: A
authors.lastname: Monereo
authors.forename: J R
authors.initials: JR
authors.lastname: Arribas
authors.forename: J
authors.initials: J
authors.lastname: Martínez Ara
authors.forename: J J
authors.initials: JJ
authors.lastname: Vázquez
mesh_terms: D005921:Glomerulonephritis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010488:Polyarteritis Nodosa / Q000209:etiology* / Q000473:pathology; D012829:Silicosis / Q000150:complications* / Q000473:pathology; D014657:Vasculitis / Q000209:etiology* / Q000473:pathology