[Status of the antioxidant system of erythrocytes in newborn infants in acute and chronic hypoxia].
Low activity of catalase, superoxide dismutase, alterations in metabolism of glutathione as well as activation of lipid peroxidation and increase in Na+, K+-ATPase activity were found in erythrocytes of newborns funic blood under conditions of chronic hypoxia and simultaneous effects of acute and chronic hypoxia. Acute hypoxia during labor caused increase in activity of superoxide dismutase, catalase, glucose-6-phosphate dehydrogenase, Na+, K+-ATPase as well as in the rate of lipid peroxidation. These alterations, observed in the enzymatic activity and in the rate of lipid peroxidation, which were detected in funic blood erythrocytes under conditions of hypoxia, may be responsible for some diseases during postnatal period of children ontogenesis.
Dubinina
E E
EE
Sofronova
L N
LN
Ramenskaia
N P
NP
Efimova
L F
LF
Petrova
Z A
ZA
D002374:Catalase / Q000097:blood; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D005311:Fetal Hypoxia / Q000097:blood*; D005954:Glucosephosphate Dehydrogenase / Q000097:blood; D005980:Glutathione Reductase / Q000097:blood; D006801:Humans; D007231:Infant, Newborn; D015227:Lipid Peroxidation; D011247:Pregnancy; D000254:Sodium-Potassium-Exchanging ATPase / Q000097:blood; D013482:Superoxide Dismutase / Q000097:blood
D005954:Glucosephosphate Dehydrogenase; D002374:Catalase; D013482:Superoxide Dismutase; D005980:Glutathione Reductase; D000254:Sodium-Potassium-Exchanging ATPase
Sostoianie antioksidantnoĭ sistemy éritrotsitov u novorozhdennykh deteĭ pri ostroĭ i khronicheskoĭ gipoksii.