Gastric glycerolipid as a receptor for Campylobacter pylori.
A species was detected in the lipid extract of human red blood cells and human and pig stomach tissue which was specifically recognised by isolates of Campylobacter pylori. The levels of this lipid were higher in human stomach antrum than in fundus and in adult compared with infant tissue samples. Chemical treatment of the purified substance suggests that it is a novel glycerolipid.
Lingwood
C A
CA
Department of Microbiology, Hospital for Sick Children, Toronto, Ontario, Canada.
Law
H
H
Pellizzari
A
A
Sherman
P
P
Drumm
B
B
D000818:Animals; D002167:Campylobacter / Q000378:metabolism*; D002852:Chromatography, Ion Exchange; D005753:Gastric Mucosa / Q000382:microbiology*; D005756:Gastritis / Q000382:microbiology; D006801:Humans; D011956:Receptors, Cell Surface; D011971:Receptors, Immunologic / Q000302:isolation & purification / Q000378:metabolism*; D013552:Swine
D011956:Receptors, Cell Surface; D011971:Receptors, Immunologic; C033639:glycolipid receptor