title: [Determination of potential carcinogenicity of nickel-containing dust using a micronuclear test].
abstract: Mutagenic activity of 3 samples of nickel-containing dusts was experimentally studied in white random-bred rats. Quantity of micronuclei in polychromatophilic erythrocytes of bone marrow smear depended on nickel dust content. Micronuclear test could be used as a rapid method for the determination of potential carcinogenic activity of polymetallic nickel-containing dusts and also as a factor confirming oncologic hazard of chemical substances combined with epidemiologic studies and chronic experiment on animals.
authors.forename: A A
authors.initials: AA
authors.lastname: Kiseleva
authors.forename: G Ia
authors.initials: GIa
authors.lastname: Lipatov
authors.forename: L N
authors.initials: LN
authors.lastname: Pylev
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Beresneva
mesh_terms: D000818:Animals; D015197:Carcinogenicity Tests; D003035:Cobalt / Q000032:analysis; D003300:Copper / Q000032:analysis; D004391:Dust / Q000032:analysis; D007501:Iron / Q000032:analysis; D015162:Micronucleus Tests; D009532:Nickel / Q000032:analysis; D051381:Rats; D012822:Silicon Dioxide / Q000032:analysis
chemical_list: D004391:Dust; D003035:Cobalt; D012822:Silicon Dioxide; D003300:Copper; D009532:Nickel; D007501:Iron
vernacular_title: Opredelenie potentsial'noĭ kantserogennosti nikel'soderzhashchikh pyleĭ s pomoshch'iu mikroiadernogo testa.