[Specific splitting of the alpha-A-globin gene by molecular forms of DNA-topoisomerase type I from calf thymus].
The specificity of splitting of the cloned alpha A-globin gene from chicken erythrocytes induced by three topoisomerases I differing in molecular masses was demonstrated. The localization and relative number of topoisomerase breaks in the alpha A-globin gene vary in different topoisomerase I forms.
Gromova
I I
II
Bronshteĭn
I B
IB
Timofeev
A V
AV
Razin
S V
SV
Kalandadze
A G
AG
D000818:Animals; D002417:Cattle; D002645:Chickens; D003001:Cloning, Molecular; D004247:DNA / Q000302:isolation & purification; D004264:DNA Topoisomerases, Type I / Q000378:metabolism*; D004587:Electrophoresis, Agar Gel; D004912:Erythrocytes / Q000032:analysis; D005914:Globins / Q000235:genetics* / Q000378:metabolism; D015151:Immunoblotting; D008970:Molecular Weight; D009710:Nucleotide Mapping; D010957:Plasmids
D005914:Globins; D004247:DNA; D004264:DNA Topoisomerases, Type I
Spetsificheskoe rasshcheplenie alpha-A-globinovogo gena molekuliarnymi formami DNK-topoizomeraz I tipa iz timusa telenka.