Appearance of a late stage during mammalian DNA replication when cells resume formation of 10 kb DNA replication intermediates.
After the joining of human large DNA replication intermediates and before the appearance of mature chromatin DNA, there exists a distinct stage--'the post-elongation stage'. This stage reappears during recovery of DNA synthesis simultaneously with the reappearance of a large DNA replication intermediate, 10 kb DNA.
Lönn
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Radiumhemmet, Karolinska Hospital, Stockholm, Sweden.
Lönn
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Nylen
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Winblad
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D016590:Aphidicolin; D004247:DNA / Q000096:biosynthesis*; D004261:DNA Replication / Q000187:drug effects; D004224:Diterpenes / Q000494:pharmacology; D004720:Endonucleases / Q000378:metabolism; D006801:Humans; D008545:Melanoma; D015719:Single-Strand Specific DNA and RNA Endonucleases; D014407:Tumor Cells, Cultured
D004224:Diterpenes; D016590:Aphidicolin; D004247:DNA; D004720:Endonucleases; D015719:Single-Strand Specific DNA and RNA Endonucleases