title: Age dependent changes in metallothionein and accumulation of cadmium in horses.
abstract: 1. Analysis of livers and kidneys from 28 horses for cadmium, zinc and metallothionein showed low cadmium content in liver. There was a gradual increase in cadmium content in kidney with age. 2. Metallothionein values varied with zinc content in the liver and with cadmium content in the kidney; copper values did not vary in either tissue. 3. Metallothionein was localized mainly in the cytoplasms in liver and kidney of horses by immunohistochemistry.
authors.affiliation: University of Illinois, Institute of Environmental Studies, Urbana 61801.
authors.forename: E H
authors.initials: EH
authors.lastname: Jeffery
authors.forename: R
authors.initials: R
authors.lastname: Noseworthy
authors.forename: M G
authors.initials: MG
authors.lastname: Cherian
mesh_terms: D000375:Aging / Q000378:metabolism*; D000818:Animals; D002104:Cadmium / Q000378:metabolism*; D003300:Copper / Q000378:metabolism; D004785:Environmental Pollutants / Q000378:metabolism; D006736:Horses / Q000378:metabolism*; D007150:Immunohistochemistry; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008668:Metallothionein / Q000378:metabolism*; D015032:Zinc / Q000378:metabolism
chemical_list: D004785:Environmental Pollutants; D002104:Cadmium; D003300:Copper; D008668:Metallothionein; D015032:Zinc