[Thymidine kinase: a serum marker in clinical medicine].
The need for new seric markers of tumoral or viral activity to enable an early diagnosis or staging has brought about a proliferation of research in new markers. The deoxi-thymidine-kinase (DTK) is an enzyme of DNA synthesis during cellular proliferation. We review the literature, concluding that DTK is a good seric marker in some neoplasias and some viral diseases because of its specificity, low cost and rapid testing in multiple samples.
Llobell Segui
G J
GJ
Blasco Ferrandiz
R F
RF
Barbero Marín
A
A
Gómez de Terreros
F J
FJ
Callol Sánchez
L
L
D000208:Acute Disease; D015415:Biomarkers / Q000097:blood; D018288:Carcinoma, Small Cell / Q000175:diagnosis; D004796:Clinical Enzyme Tests / Q000379:methods; D006689:Hodgkin Disease / Q000175:diagnosis; D006801:Humans; D007527:Isoenzymes / Q000097:blood; D007938:Leukemia / Q000175:diagnosis; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000175:diagnosis; D008175:Lung Neoplasms / Q000175:diagnosis; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis; D013937:Thymidine Kinase / Q000097:blood*
D015415:Biomarkers; D007527:Isoenzymes; D013937:Thymidine Kinase
Timidina quinasa: un marcador sérico en medicina clínica.