title: Benzodiazepine prescription abuse and the benzodiazepine withdrawal syndrome.
abstract: Benzodiazepines are among the most widely-prescribed medications in the world. Although tolerance is unlikely, abuse is widespread. Prescription abuse is especially common, with medication being taken for longer periods than intended, or at the wrong dosage, or for purposes not intended by the physician. Prolonged use, even at therapeutic levels, can produce a definite "benzodiazepine withdrawal syndrome" with disturbing symptoms such as insomnia, twitching, and restlessness, leading to prolongation of the already inappropriate usage. Suggestions for reducing this abuse are discussed.
authors.forename: H R
authors.initials: HR
authors.lastname: Olivier
mesh_terms: D000328:Adult; D000368:Aged; D017109:Akathisia, Drug-Induced; D014151:Anti-Anxiety Agents / Q000009:adverse effects*; D001569:Benzodiazepines; D011307:Drug Prescriptions; D005260:Female; D006212:Hallucinations / Q000139:chemically induced; D006801:Humans; D013375:Substance Withdrawal Syndrome / Q000209:etiology*; D019966:Substance-Related Disorders / Q000150:complications*
chemical_list: D014151:Anti-Anxiety Agents; D001569:Benzodiazepines