One of 8 women with bladder neoplasia may have concomitant gastrointestinal pathology, including cancer.
A study of the pathology records during 6 years for 160 women with bladder neoplasia and 150 with malignant melanoma revealed differences in patient experience in regard to the incidence of surgical biopsies. Biopsy for additional skin lesions was common in melanoma patients, who produced few gastrointestinal lesions. In contrast, 19 of the bladder cancer patients produced 26 gastrointestinal lesions, including 5 carcinomas. The latter incidence is higher than expected in our population. This difference between the 2 sets of patients in regard to skin and gastrointestinal lesions is statistically significant. Few gynecological lesions were noted in either group but a common factor was human papillomavirus infection, as indicated by the presence of koilocytosis. The latter also was present in 17 per cent of 41 otherwise negative smears from patients with bladder neoplasia, that is considerably more than expected (less than 1 per cent), and is similar to that reported previously in patients with melanoma.
Hartveit
F
F
Department of Pathology, Gade Institute, University of Bergen, Norway.
Maehle
B O
BO
D005260:Female; D005767:Gastrointestinal Diseases / Q000150:complications*; D005770:Gastrointestinal Neoplasms; D006801:Humans; D008545:Melanoma; D009378:Neoplasms, Multiple Primary; D027383:Papillomaviridae; D012878:Skin Neoplasms; D014412:Tumor Virus Infections / Q000150:complications; D001749:Urinary Bladder Neoplasms / Q000150:complications*; D002578:Uterine Cervical Dysplasia / Q000150:complications / Q000473:pathology