Physiology and molecular biology of the renal Na/H antiporter.
The renal Na/H antiporter is involved in cell pH regulation and, predominantly in the proximal tubule, also mediates transcellular NaCl and NaHCO3 transport. The transporter is regulated by systemic acid-base factors and hormones such as angiotensin II, PTH, glucocorticoids and alpha2-adrenergics. The human gene of the Na/H antiporter has been cloned and sequenced recently.
Krapf
R
R
Department of Medicine, Insel University Hospital, Berne, Switzerland.
D000136:Acid-Base Equilibrium; D000818:Animals; D002352:Carrier Proteins / Q000235:genetics / Q000502:physiology*; D003001:Cloning, Molecular; D006801:Humans; D007687:Kidney Tubules, Proximal / Q000502:physiology*; D017923:Sodium-Hydrogen Exchangers
D002352:Carrier Proteins; D017923:Sodium-Hydrogen Exchangers