The impact of EBV hybridization in clinical and biological medicine.
Hybridization technology allows the detection of EBV (Epstein-Barr Virus) DNA in lymphoproliferative diseases in immunosuppressed patients. Moreover, in HIV infected patients, LIP (Lymphocytic Interstitial Pneumonitis), hairy leucoplasia and lymphoma are associated with EBV by DNA hybridization. These procedures are also useful for understanding interactions between EBV and epithelial cells.
Morinet
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Service de Bactériologie-Virologie, Hôpital Saint-Louis, Université Paris VII, France.
D002051:Burkitt Lymphoma / Q000382:microbiology / Q000473:pathology; D004273:DNA, Neoplasm / Q000032:analysis; D004279:DNA, Viral / Q000032:analysis*; D004848:Epithelium / Q000382:microbiology; D006566:Herpesviridae Infections / Q000150:complications / Q000175:diagnosis*; D004854:Herpesvirus 4, Human / Q000302:isolation & purification* / Q000502:physiology; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000382:microbiology; D008214:Lymphocytes / Q000382:microbiology; D008232:Lymphoproliferative Disorders / Q000382:microbiology; D009693:Nucleic Acid Hybridization; D014412:Tumor Virus Infections / Q000175:diagnosis*; D014779:Virus Replication
D004273:DNA, Neoplasm; D004279:DNA, Viral