Aujeszky's disease ELISA: cross-reactions with other herpesvirus antisera.
The production of antibodies in pigs to 11 herpesviruses was investigated in relation to their ability to cross-react with Aujeszky's disease virus (suid herpesvirus 1--SHV1). Of the herpesviruses tested only two, sheep herpesvirus (caprine herpesvirus 1) and dog herpesvirus (canid herpesvirus 1), failed to produce homologous virus antibodies. Only the antibodies to bovine herpesvirus 1 (BHV1) produced a cross-reaction by SHV1 enzyme-linked immunosorbent assay (ELISA). No SHV1 neutralizing antibodies were detected in any of the herpesvirus antisera. A cross-reaction with SHV1 by a serum from a pig naturally infected with BHV1 or with any of the other herpesviruses tested was considered unlikely.
Banks
M
M
Virology Department, Central Veterinary Laboratory, Weybridge, Surrey, Gt. Britain.
D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D003429:Cross Reactions; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary*; D005189:False Positive Reactions; D006564:Herpesviridae / Q000276:immunology*; D011558:Herpesvirus 1, Suid / Q000276:immunology*; D007106:Immune Sera / Q000276:immunology; D013552:Swine / Q000276:immunology*
D000914:Antibodies, Viral; D007106:Immune Sera