Cross-adapted sugar responses in the mouse taste cell.
1. Intracellular recordings of mouse taste cell responses were made using a glass micro-electrode filled with Procion yellow dye solution. 2. Six sugars (sucrose, maltose, lactose, glucose, galactose and fructose) produced the depolarization responses. 3. Gustatory cross adaptation between sugars was determined. When the taste cell was pre-adapted with one of the six sugars, the other five sugars, cross adapted, produced depolarization, hyperpolarization or null responses. 4. From these observations, it is suggested that there are multiple sugar receptor sites on the receptor membrane of the mouse taste cell.
Tonosaki
K
K
Department of Oral Physiology, School of Dentistry, Asahi University, Gifu, Japan.
Funakoshi
M
M
D000222:Adaptation, Physiological; D000818:Animals; D002241:Carbohydrates / Q000494:pharmacology*; D004594:Electrophysiology; D051379:Mice / Q000502:physiology*; D008813:Mice, Inbred ICR; D013268:Stimulation, Chemical; D013649:Taste / Q000502:physiology*; D014059:Tongue / Q000166:cytology / Q000502:physiology*
D002241:Carbohydrates