'Cured' myasthenia gravis and neuromuscular blockade.
A symptomless myasthenic patient who played representative squash received 0.1 mg/kg of vecuronium and enflurane as part of a general anaesthetic for elective gynaecological surgery. Neuromuscular block was prolonged. The effect of neuromuscular blocking agents and volatile anaesthetics in symptomless myasthenics is discussed. We conclude that these patients should be assumed to be sensitive to such agents.
Lumb
A B
AB
Department of Anaesthesia, Royal Free Hospital, Hampstead, London.
Calder
I
I
D000328:Adult; D000768:Anesthesia, General; D004357:Drug Synergism; D004737:Enflurane / Q000494:pharmacology; D005260:Female; D006801:Humans; D009119:Muscle Contraction / Q000187:drug effects; D009157:Myasthenia Gravis / Q000150:complications*; D013997:Time Factors; D014673:Vecuronium Bromide / Q000494:pharmacology*
D014673:Vecuronium Bromide; D004737:Enflurane