Role of cerebral endothelium in brain oedema.
The view that cerebral endothelial cells represent the cellular basis of the blood-brain barrier has been generally accepted. The regulation of transport processes operating in the cerebral endothelial cells is currently of great interest. Our knowledge of these regulatory mechanisms is briefly reviewed here with special regard to the molecular processes involved in the formation of brain oedema and emphasis on new therapeutic means for its prevention.
Joo
F
F
Institute of Neurological and Communicative Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
Klatzo
I
I
D001921:Brain / Q000098:blood supply / Q000503:physiopathology*; D001929:Brain Edema / Q000145:classification / Q000503:physiopathology* / Q000628:therapy; D004727:Endothelium / Q000503:physiopathology; D006801:Humans