title: Alveolar cell carcinoma complicating sickle cell anemia: a chance occurrence?
abstract: Alveolar cell carcinoma, a neoplasm associated with pre-existing inflammatory lung disease, has not been reported previously in patients with sickle cell disease. We present such a patient and suggest that chronic pulmonary scarring in this setting predisposed to development of his malignancy. As survival increases in individuals with sickle cell disease, alveolar cell carcinoma must be considered in these differential diagnosis of otherwise unexplained chronic pulmonary infiltrates.
authors.affiliation: Department of Medicine State University Medical Center, New Orleans.
authors.forename: M
authors.initials: M
authors.lastname: Labi
authors.forename: E F
authors.initials: EF
authors.lastname: Haponik
authors.forename: R A
authors.initials: RA
authors.lastname: Welsh
authors.forename: W R
authors.initials: WR
authors.lastname: Summer
mesh_terms: D002282:Adenocarcinoma, Bronchiolo-Alveolar / Q000209:etiology* / Q000473:pathology; D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications*; D001706:Biopsy; D001999:Bronchoscopy; D005336:Fiber Optic Technology; D006801:Humans; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000000981:diagnostic imaging / Q000209:etiology; D008175:Lung Neoplasms / Q000209:etiology* / Q000473:pathology; D008297:Male; D013902:Radiography, Thoracic