Discrepancy in hormone binding and information transfer between sister cells of Tetrahymena clones.
Tetrahymena cells treated with insulin in mass cultures were separated to single-cell clones or one of the "sister-cells" of dividing Tetrahymena (in single-cell culture) was treated with insulin. In both cases the FITC-insulin binding of sister-cells were compared. The insulin imprinting significantly increased the insulin binding of cells. There was also a significant difference between the imprinted and not imprinted sisters as well as between the not imprinted sisters. This demonstrates the existence of a difference (in hormone binding) between sister-cells and justifies that the information of the first hormone treatment (imprinting) is not equally divided between the sister-cells.
Csaba
G
G
Kovács
P
P
László
V
V
D000818:Animals; D002450:Cell Communication; D011972:Receptor, Insulin / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000378:metabolism*; D013768:Tetrahymena / Q000502:physiology*
D011956:Receptors, Cell Surface; D011972:Receptor, Insulin