[Comparison of DNA interaction with sphingomyelin, spermine and magnesium ions using a spin label method].
Identical interactions of liposomes from sphingomyelin, spermine and magnesium ions with DNA was shown by spin probe method using spin-labeled 9-aminoacridine. The interactions proceed in the phosphate groups at the expense of hydrophobic part of phospholipid. The functional role of sphingomyelin--DNA interaction in matrix biosyntheses is discussed.
Krasil'nikov
V A
VA
Mil'
E M
EM
Alesenko
A V
AV
Biniukov
V M
VM
D004247:DNA / Q000187:drug effects*; D004578:Electron Spin Resonance Spectroscopy; D008081:Liposomes; D008274:Magnesium / Q000494:pharmacology*; D009690:Nucleic Acid Conformation / Q000187:drug effects*; D013096:Spermine / Q000494:pharmacology*; D013109:Sphingomyelins / Q000494:pharmacology*; D013113:Spin Labels
D008081:Liposomes; D013109:Sphingomyelins; D013113:Spin Labels; D013096:Spermine; D004247:DNA; D008274:Magnesium
Sravnenie vzaimodeĭstviia DNK so sfingomielinom, sperminom i ionami magniia metodom spinovykh zondov.