title: Preeclampsia: a hyperdynamic disease model.
abstract: Preeclampsia is a common disease and as such is a significant contributor to maternal and neonatal morbidity and mortality. Despite the ubiquity of the disease and its public health impact, no comprehensive mechanism has been established. Therapy has been limited to bed rest and premature delivery. The purpose of this article is to examine preeclampsia from a hemodynamic point of view and to advance a hypothesis of disease mechanism.
authors.affiliation: Department of Obstetrics and Gynecology, University of Washington, Seattle.
authors.forename: T R
authors.initials: TR
authors.lastname: Easterling
authors.forename: T J
authors.initials: TJ
authors.lastname: Benedetti
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000818:Animals; D001794:Blood Pressure; D014676:Diet, Vegetarian; D004044:Dietary Proteins / Q000008:administration & dosage; D005260:Female; D005919:Glomerular Filtration Rate; D006439:Hemodynamics; D006801:Humans; D007668:Kidney / Q000503:physiopathology; D008137:Longitudinal Studies; D011225:Pre-Eclampsia / Q000178:diet therapy / Q000188:drug therapy / Q000503:physiopathology*; D011247:Pregnancy; D051381:Rats; D012079:Renal Circulation
chemical_list: D000319:Adrenergic beta-Antagonists; D004044:Dietary Proteins