[Myocardial disease, heart failure and reactional tuberculoid leprosy].
A 60-year-old woman was admitted with congestive heart failure, essential hypertension and abdominal distension. Her son reported that she appeared with red spots in the body and that she was under dapsone therapy. Seven months ago there was sudden increase of the skin lesions. In the 11th day after admission she underwent a stroke that progressed to decerebration and she expired on the fourth day. Autopsy confirmed CHF due to chronic myocarditis related to Chagas' disease. Aneurysm of the apical region of the left ventricular chamber was also observed leading to thrombosis and systemic embolism with brain and spleen hemorrhagic infarct. In the encephalous there was edema, uncus herniation and hemorrhagic infarct of the brain stem. The skin lesions were due to reactional tuberculoid hanseniasis (RHT) with focal lesions in axillary lymphnodes, nasopharyngeal mucosa and in the posterior tibial nerve. The pathogenesis of RHT is discussed as well as its differentiation with the BT group of Ridley and Jopling and its probably relationship with the secondary tuberculoid hanseniasis reported by Ridley. The focal lesions are also discussed with END to the involvement of a peripheral nerve trunk what is said to be uncommon in this form of Hansen's disease.
Opromolla
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DV
Divisão de Ensino e Pesquisa Instituto Lauro de Souza Lima Bauru, Estado da Saúde de São Paulo.
Fleury
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RN
D001161:Arteriosclerosis / Q000473:pathology; D002598:Chagas Cardiomyopathy / Q000473:pathology*; D004562:Electrocardiography; D005260:Female; D006333:Heart Failure / Q000473:pathology*; D006801:Humans; D015441:Leprosy, Tuberculoid / Q000473:pathology*; D007958:Leukocyte Count; D007962:Leukocytes / Q000737:chemistry; D008875:Middle Aged; D013927:Thrombosis / Q000473:pathology
Seção anátomo-clínica.