Neuromyelitis optica (Devic's disease) report of one case.
Neuromyelitis optica also named Devic's disease is an acute combined optic neuritis and transverse myelitis. It is thought to be a variant of multiple sclerosis, but its clinical presentation probably has only one attack without further recurrence and exacerbation. We present a 12-year-old girl who suffered from sudden onset of lower extremeties weakness, sensory loss and blurred vision after a prodromal URI symptom. CSF examination showed mild pleocytosis, elevated immunoglobulins, mild elevation of protein concentration. No oligoclonal band was detected. Serum virology showed high titer of anti-EB virus antibody. Visual evoke potential showed prolong of latency and decreased amplitude of both eyes. After prednisolone treatment, her visual accuity began to improve on the 7th hospital day and motor function improved on the 11th hospital day. Two years later, she has normal visual accuity, normal motor function and shows no evidence of disease recurrence.
Ko
F J
FJ
Chiang
C H
CH
Jong
Y J
YJ
Chang
C H
CH
D000914:Antibodies, Viral / Q000032:analysis; D002648:Child; D003711:Demyelinating Diseases / Q000188:drug therapy / Q000276:immunology; D005260:Female; D004854:Herpesvirus 4, Human / Q000276:immunology; D006801:Humans; D009471:Neuromyelitis Optica / Q000188:drug therapy / Q000276:immunology; D011239:Prednisolone / Q000627:therapeutic use
D000914:Antibodies, Viral; D011239:Prednisolone