title: Life stress and lymphocyte alterations among patients with rheumatoid arthritis.
abstract: The relation between life stress and immune parameters was investigated for 33 female rheumatoid arthritis (RA) patients interviewed during three routine monthly clinic checkups. Life stress from major and minor events, coping efficacy, and self-reported psychological distress were assessed, and immunofluorescence of T-cells and B-cells was performed on the blood drawn during each visit. Small stressful events were positively related to the proportion of circulating B-cells, psychological distress was inversely related to proportion of circulating T-cells, and major life events were associated with lower T-helper/T-suppressor cell ratios.
authors.affiliation: Department of Psychology, Arizona State University, Tempe 85287.
authors.forename: A J
authors.initials: AJ
authors.lastname: Zautra
authors.forename: M A
authors.initials: MA
authors.lastname: Okun
authors.forename: S E
authors.initials: SE
authors.lastname: Robinson
authors.forename: D
authors.initials: D
authors.lastname: Lee
authors.forename: S H
authors.initials: SH
authors.lastname: Roth
authors.forename: J
authors.initials: J
authors.lastname: Emmanual
mesh_terms: D000223:Adaptation, Psychological / Q000502:physiology; D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000276:immunology / Q000523:psychology*; D001402:B-Lymphocytes / Q000276:immunology; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008016:Life Change Events; D008875:Middle Aged; D011581:Psychological Tests; D011602:Psychophysiologic Disorders / Q000276:immunology / Q000523:psychology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology