title: Significance of epididymal and ductal anomalies associated with testicular maldescent.
abstract: Epididymal abnormalities have long been found in conjunction with cryptorchid testicles. The aim of this study was to document the different types of epididymal and ductal anomalies in relation to the position of the cryptorchid testis and to determine their clinical significance. Exploration was performed on 187 cryptorchid testes in 174 boys. The position of the testis and the epididymal and ductal anomalies were documented at operation. A biopsy was taken from the testis or atretic spermatic cord structures for light microscopy. Epididymal, ductal and/or testicular anomalies were detected in 43 per cent of the 187 testes, including anomalies of ductal fusion, anomalies of ductal suspension and anomalies associated with absent or vanishing testes. Biopsy of the testes with severe anomalies of ductal fusion showed preservation of germ cells in 69 per cent and diminished germ cells in 31 per cent. The higher the arrest of testicular descent, the more grossly abnormal was the associated ductal system. Early successful orchiopexy alone may not ensure subsequent fertility despite the presence of normal germ cells.
authors.affiliation: Division of Pediatric Urology, Jack D. Weiler Hospital, Albert Einstein College of Medicine, Bronx, New York.
authors.forename: B
authors.initials: B
authors.lastname: Gill
authors.forename: S
authors.initials: S
authors.lastname: Kogan
authors.forename: S
authors.initials: S
authors.lastname: Starr
authors.forename: E
authors.initials: E
authors.lastname: Reda
authors.forename: S
authors.initials: S
authors.lastname: Levitt
mesh_terms: D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D003456:Cryptorchidism / Q000473:pathology*; D004822:Epididymis / Q000002:abnormalities*; D006801:Humans; D007223:Infant; D008297:Male; D013737:Testis / Q000002:abnormalities; D014649:Vas Deferens / Q000002:abnormalities*