title: The effect of a dentifrice containing soluble pyrophosphate and a copolymer on calculus deposit: a six-month clinical study.
abstract: A six-month, double blind, cross over clinical study was conducted to compare the effect of a commercially available anticalculus dentifrice and a placebo dentifrice on supragingival calculus deposits. Fifty adult subjects who entered the study were given an oral prophylaxis and were assigned to use either pyrophosphate/copolymer toothpaste or a placebo toothpaste for a period of three months. They were then scored for calculus deposits using the Volpe-Manhold method, received a second oral prophylaxis and used the alternate dentifrice for a second three month period of time. The subjects were again scored for calculus deposits and the study was completed. The results indicated that pyrophosphate/copolymer toothpaste reduced supragingival calculus formation by 37.07%, as compared to the placebo dentifrice. This reduction was significant at the 99% level of confidence.
authors.forename: T
authors.initials: T
authors.lastname: Triratana
authors.forename: V
authors.initials: V
authors.lastname: Kerdvongbundit
authors.forename: N
authors.initials: N
authors.lastname: Chutapimol
authors.forename: S
authors.initials: S
authors.lastname: Thepbanterng
mesh_terms: D000328:Adult; D002986:Clinical Trials as Topic; D003728:Dental Calculus / Q000517:prevention & control*; D003802:Dentifrices / Q000627:therapeutic use*; D011756:Diphosphates / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D003802:Dentifrices; D011756:Diphosphates