title: Comparison of delayed imaging with Tc-99m PMT and Tc-99m DEIDA for visualization of hepatoma.
abstract: Delayed imaging was performed after the intravenous administration of Tc-99m DEIDA and Tc-99m PMT in 18 patients with hepatocellular carcinoma. Using Tc-99m DEIDA imaging, sharp uptake by liver tumors was observed in four patients (22%), but the uptake was similar to that of the surrounding normal liver in eight patients (44%). Using Tc-99m PMT imaging, the uptake by the tumor was notable in ten patients (56%) and normal in two (11%). Tc-99m PMT and Tc-99m DEIDA were both concentrated in hepatocellular carcinomas, but the former showed intense uptakes more frequently, and thus is suggested to be useful in the diagnosis of hepatocellular carcinoma.
authors.affiliation: Department of Nuclear Medicine, Center for Adults Diseases, Osaka, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Hasegawa
authors.forename: S
authors.initials: S
authors.lastname: Nakano
authors.forename: T
authors.initials: T
authors.lastname: Hashizume
authors.forename: A
authors.initials: A
authors.lastname: Noguchi
authors.forename: K
authors.initials: K
authors.lastname: Ibuka
authors.forename: H
authors.initials: H
authors.lastname: Kasugai
authors.forename: J
authors.initials: J
authors.lastname: Kojima
authors.forename: S
authors.initials: S
authors.lastname: Ishigami
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007098:Imino Acids; D007668:Kidney / Q000000981:diagnostic imaging; D008099:Liver / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D009942:Organometallic Compounds; D015609:Organotechnetium Compounds; D011859:Radiography; D011877:Radionuclide Imaging; D013667:Technetium; D019784:Technetium Tc 99m Diethyl-iminodiacetic Acid; D014364:Tryptophan / Q000031:analogs & derivatives*
chemical_list: D007098:Imino Acids; D009942:Organometallic Compounds; D015609:Organotechnetium Compounds; D019784:Technetium Tc 99m Diethyl-iminodiacetic Acid; C034836:technetium Tc 99m (Sn)-N-pyridoxyl-5-methyltryptophan; D013667:Technetium; D014364:Tryptophan