Phthaloyl-glycylP-isoleucyl-tryptophan benzylamide is a potent inhibitor of human skin fibroblast collagenase with a Ki of 25 nM.
Kortylewicz
Z P
ZP
Department of Biochemistry, University of Kentucky, Lexington 40536.
Galardy
R E
RE
D000595:Amino Acid Sequence; D001665:Binding Sites; D005347:Fibroblasts / Q000201:enzymology; D006801:Humans; D007700:Kinetics; D003012:Microbial Collagenase / Q000037:antagonists & inhibitors*; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000494:pharmacology*; D012867:Skin / Q000201:enzymology*
D009842:Oligopeptides; C067307:phthaloyl-glycyl(P)-isoleucyl-tryptophyl-benzylamide; D003012:Microbial Collagenase