title: [Peripheral neuropathies caused by drugs].
abstract: Peripheral neuropathy is a common manifestation of chemotherapeutic agents. Most drugs produce a distal axonal degeneration and long axons are predominantly affected, giving a clinical picture characterized by a symmetrical sensory neuropathy. The toxicity of therapeutic agents to the peripheral nervous system particularly includes those used in cancer-chemotherapy (cisplatin, vinca alkaloids), but antimicrobial agents such as isoniazide or nitrofurantoin and vitamin abuse (pyridoxine) are also discussed.
authors.forename: P A
authors.initials: PA
authors.lastname: Uldry
authors.forename: F
authors.initials: F
authors.lastname: Regli
mesh_terms: D000890:Anti-Infective Agents / Q000009:adverse effects; D000970:Antineoplastic Agents / Q000009:adverse effects; D001369:Axons / Q000187:drug effects; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D009468:Neuromuscular Diseases / Q000139:chemically induced*; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced*
chemical_list: D000890:Anti-Infective Agents; D000970:Antineoplastic Agents
vernacular_title: Neuropathies périphériques d'origine médicamenteuse.