Still's disease associated with adenovirus infection and defect in adenovirus directed natural killing.
Low natural killer (NK) activity towards adenovirus infected fibroblasts was detected in the peripheral blood of a child with Still's disease and was not normalised by the addition of interferon alfa or interleukin 2. NK cytotoxicity directed at K 562 target cells or polio infected fibroblasts was normal. This specific NK deficiency might have contributed to the development of the child's Still's disease.
Luder
A S
AS
Department of Pediatrics, Carmel Hospital (Faculty of Medicine, Technion-Israel Institute of Technology), Haifa.
Naphtali
V
V
Ben Porat
E
E
Lahat
N
N
D000257:Adenoviridae Infections / Q000276:immunology*; D000258:Adenovirus Infections, Human / Q000276:immunology*; D001170:Arthritis, Infectious / Q000276:immunology*; D001171:Arthritis, Juvenile / Q000276:immunology*; D003602:Cytotoxicity, Immunologic; D006801:Humans; D007223:Infant; D007694:Killer Cells, Natural / Q000276:immunology*; D008297:Male