Does thermotolerance occur in human red cells?
Osmotic fragility and autohemolysis were used as endpoints in the measurement of damage to the plasma membrane in human erythrocytes, after single or double heat treatments. Injury recorded above 46 degrees C, and the induction of thermotolerance in the enucleate cells after a primary heat treatment of 44 degrees C for 15 min, indicates that the plasma membrane plays an important role in heat injury and in thermotolerance.
Koter
M
M
Department of Biophysics, University of Lodz, Poland.
Laski
J
J
D000222:Adaptation, Physiological; D004910:Erythrocyte Membrane / Q000502:physiology*; D006461:Hemolysis; D006358:Hot Temperature / Q000009:adverse effects*; D006801:Humans; D066298:In Vitro Techniques; D009996:Osmotic Fragility