Haemodynamic effects of vecuronium.
Three hundred and twenty adults (ASA grade I, both sexes), received diazepam 10 mg by mouth (50% received atropine 7 micrograms kg-1 in addition) i.m. 45 min before operation. Patients were then allocated randomly to undergo general anaesthesia with either a nitrous oxide-neurolept technique or nitrous oxide-halothane. Vecuronium was administered to 50% of the patients in each anaesthetic group and heart rate and arterial pressure were monitored. Vecuronium did not influence heart rate, or systolic or diastolic arterial pressures.
Wierda
J M
JM
Research Group of the Institutes for Experimental Anesthesiology and Clinical Pharmacology, The Netherlands.
Maestrone
E
E
Bencini
A F
AF
Boyer
A
A
Rashkovsky
O M
OM
Lip
H
H
Karliczek
R
R
Ket
J M
JM
Agoston
S
S
D000328:Adult; D000768:Anesthesia, General; D001285:Atropine / Q000494:pharmacology; D005260:Female; D006221:Halothane / Q000494:pharmacology; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008297:Male; D009458:Neuroleptanalgesia; D013997:Time Factors; D014673:Vecuronium Bromide / Q000494:pharmacology*
D001285:Atropine; D014673:Vecuronium Bromide; D006221:Halothane