[Some pharmacologic comments on the action of glycine derivatives in relation to peculiarities of the central glycinergic system].
The antagonism of the effect of reserpine on the thermoregulation in rats, the potentiation of the reserpine catalepsy with the simultaneous increase of the irritability of rats, the hyperthermia in mice, etc., obtained with some new glycine derivatives, are discussed in relation with recent data on the distribution of the strychnine-sensitive, or strychnine-insensitive-glutamatergic (NMDA) activating, glycinergic receptors.
Vamvakidès
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D000818:Animals; D001833:Body Temperature Regulation / Q000187:drug effects; D001921:Brain / Q000187:drug effects; D005998:Glycine / Q000031:analogs & derivatives / Q000494:pharmacology*; D051379:Mice; D051381:Rats; D017981:Receptors, Neurotransmitter / Q000187:drug effects* / Q000502:physiology; D012110:Reserpine / Q000494:pharmacology
D017981:Receptors, Neurotransmitter; D012110:Reserpine; D005998:Glycine
Quelques observations pharmacologiques sur l'action des dérivés de la glycine en relation avec des particularités du système glycinergique central.