title: In vitro studies into some parameters of protein and carbohydrate metabolism in lymphocytes infected with bovine leucosis virus.
abstract: Several parameters of protein and carbohydrate metabolism were determined in normal and leukemic lymphocytes in vitro in cattle, including arylamidase activity toward beta-naphthylamides of L-amino acids. The homogenate of bovine leukemic lymphocytes, in comparison with the control revealed increase of gamma-glutamyltransferase, activity trypsin inhibitor and papain inhibitor concentration and aldolase activity. On the other hand, proteolytic activity toward casein and histomucoid content decreased. Out of the 7 substrates used in the study, only 2, alanyl-beta-naphthylamide and leucyl-beta-naphthylamide, demonstrated lower activity in the leukemic material. Disorders in carbohydrate and protein metabolism in the observed lymphocytes in vitro in cattle are presented in the paper.
authors.forename: J A
authors.initials: JA
authors.lastname: Madej
authors.forename: K A
authors.initials: KA
authors.lastname: Sobiech
authors.forename: S
authors.initials: S
authors.lastname: Klimentowski
mesh_terms: D000818:Animals; D050260:Carbohydrate Metabolism; D002417:Cattle; D002418:Cattle Diseases / Q000378:metabolism*; D002478:Cells, Cultured; D005260:Female; D007938:Leukemia / Q000378:metabolism / Q000662:veterinary*; D001909:Leukemia Virus, Bovine; D008214:Lymphocytes / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism*
chemical_list: D011506:Proteins