title: The efficacy of benorylate in postoperative dental pain.
abstract: The efficacy of a single pre-operative dose of benorylate (4 g) was determined in a double-blind, randomized, placebo-controlled parallel study in patients undergoing removal of a single impacted lower third molar. Patients treated with benorylate 4 g reported significantly less pain between 3-6 h after dosage than those treated with placebo. Overall pain scores at 6 h were significantly less in the benorylate group than the placebo group. However, overall pain scores at 12 h did not differ significantly between treatment groups. It is concluded from this study that a single dose of benorylate 4 g given immediately prior to the removal of an impacted lower third molar provides limited pain control during the postoperative period.
authors.affiliation: Department of Oral Surgery, Dental School, Newcastle upon Tyne, UK.
authors.forename: U
authors.initials: U
authors.lastname: Moore
authors.forename: R A
authors.initials: RA
authors.lastname: Seymour
authors.forename: F M
authors.initials: FM
authors.lastname: Williams
authors.forename: E
authors.initials: E
authors.lastname: Nicholson
authors.forename: M D
authors.initials: MD
authors.lastname: Rawlins
mesh_terms: D000082:Acetaminophen / Q000627:therapeutic use; D000293:Adolescent; D000328:Adult; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008964:Molar, Third / Q000601:surgery*; D010149:Postoperative Pain / Q000188:drug therapy*; D011897:Random Allocation; D012459:Salicylates / Q000627:therapeutic use*; D014081:Tooth Extraction; D014095:Tooth, Impacted / Q000601:surgery*
chemical_list: D012459:Salicylates; D000082:Acetaminophen