title: BHT-920 and LY-171555 (quinpirole) have similar affinities for striatal D-2 dopamine receptors, and similar affinities for striatal D-1 dopamine receptors.
abstract: The affinity of LY-171555 (quinpirole) and BHT-920 for both states of rat striatal dopamine D-1 and D-2 receptors was determined. Although these drugs have different pharmacological effects in experimental animals, we found that they had similar affinities for both D-1 and D-2 receptors.
authors.affiliation: Laboratori de Neuropsicofarmacologia, Programa Sant Pau-CITRAN, Hospital de la Santa Creu i de Sant Pau, Barcelona, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Ferré
authors.forename: T
authors.initials: T
authors.lastname: Guix
authors.forename: J
authors.initials: J
authors.lastname: Sallés
authors.forename: L
authors.initials: L
authors.lastname: Cuffí
authors.forename: A
authors.initials: A
authors.lastname: Badia
authors.forename: M
authors.initials: M
authors.lastname: Casas
mesh_terms: D000818:Animals; D001381:Azepines / Q000378:metabolism*; D001552:Benzazepines / Q000494:pharmacology; D003342:Corpus Striatum / Q000378:metabolism*; D015259:Dopamine Agents / Q000378:metabolism*; D016232:Endothelins; D004873:Ergolines / Q000378:metabolism*; D006165:Guanylyl Imidodiphosphate / Q000494:pharmacology; D066298:In Vitro Techniques; D008297:Male; D010455:Peptides / Q000494:pharmacology*; D019257:Quinpirole; D051381:Rats; D011919:Rats, Inbred Strains; D011954:Receptors, Dopamine / Q000378:metabolism*
chemical_list: D001381:Azepines; D001552:Benzazepines; D015259:Dopamine Agents; D016232:Endothelins; D004873:Ergolines; D010455:Peptides; D011954:Receptors, Dopamine; D019257:Quinpirole; D006165:Guanylyl Imidodiphosphate; C024763:talipexole