title: Fertility in a male with trisomy 21.
abstract: We review the published reports on reproduction in cases of non-mosaic trisomy 21 (Down's syndrome) and present the first fully documented case of a non-mosaic male with Down's syndrome fathering a pregnancy, a fact which has important implications in the light of caring for these people in the community.
authors.affiliation: Division of Medical and Molecular Genetics, United Medical School, Guy's Hospital, London.
authors.forename: R
authors.initials: R
authors.lastname: Sheridan
authors.forename: J
authors.initials: J
authors.lastname: Llerena
authors.forename: S
authors.initials: S
authors.lastname: Matkins
authors.forename: P
authors.initials: P
authors.lastname: Debenham
authors.forename: A
authors.initials: A
authors.lastname: Cawood
authors.forename: M
authors.initials: M
authors.lastname: Bobrow
mesh_terms: D000328:Adult; D004247:DNA / Q000032:analysis; D004314:Down Syndrome / Q000235:genetics*; D005298:Fertility; D006801:Humans; D008297:Male; D009030:Mosaicism; D010334:Paternity; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D004247:DNA