Selective staining of a population of parvalbumin-containing GABAergic neurons in the rat cerebral cortex by lectins with specific affinity for terminal N-acetylgalactosamine.
Lectins with specific affinity for terminal N-acetylgalactosamine, Vicia villosa agglutinin (VVA) and Glycine max agglutinin (soybean agglutinin; SBA), are shown to stain selectively a subpopulation of GABAergic neurons in the rat cerebral cortex. About 90% of VAA- and/or SBA-stained cells are also parvalbumin-immunoreactive, but no VVA-stained cells showed somatostatin-28-like or cholecystokinin-8-like immunoreactivities.
Kosaka
T
T
National Institute for Physiological Sciences, Okazaki, Japan.
Heizmann
C W
CW
D000116:Acetylgalactosamine / Q000378:metabolism*; D000818:Animals; D002540:Cerebral Cortex / Q000166:cytology* / Q000378:metabolism; D005688:Galactosamine / Q000031:analogs & derivatives*; D006651:Histocytochemistry / Q000379:methods*; D037102:Lectins; D008297:Male; D009124:Muscle Proteins / Q000378:metabolism*; D009474:Neurons / Q000145:classification / Q000378:metabolism*; D010320:Parvalbumins / Q000378:metabolism*; D037121:Plant Lectins; D051381:Rats; D011919:Rats, Inbred Strains; D012844:Sincalide / Q000378:metabolism; D013004:Somatostatin / Q000378:metabolism; D053561:Somatostatin-28; D030262:Soybean Proteins; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*; D010835:Phytohemagglutinins
D000116:Acetylgalactosamine; D005688:Galactosamine; D037102:Lectins; D009124:Muscle Proteins; D010320:Parvalbumins; D037121:Plant Lectins; D012844:Sincalide; D013004:Somatostatin; D053561:Somatostatin-28; D030262:Soybean Proteins; D005680:gamma-Aminobutyric Acid; C042242:Vicia lectins; C028824:soybean lectin; D010835:Phytohemagglutinins