Potential mechanism of pulmonary arterial relaxation and guanylate cyclase activation by 15-hydroperoxyeicosatetraenoic acid.
Wolin
M S
MS
Department of Physiology, New York Medical College, Valhalla 10595.
Burke-Wolin
T
T
Cohn
L A
LA
Cherry
P D
PD
D000818:Animals; D002417:Cattle; D004789:Enzyme Activation; D006162:Guanylate Cyclase / Q000378:metabolism*; D066298:In Vitro Techniques; D007700:Kinetics; D015289:Leukotrienes / Q000494:pharmacology*; D008054:Lipid Peroxides / Q000494:pharmacology*; D008962:Models, Theoretical; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000502:physiology*; D011651:Pulmonary Artery / Q000187:drug effects / Q000502:physiology*; D014664:Vasodilation / Q000187:drug effects*
D015289:Leukotrienes; D008054:Lipid Peroxides; C025086:15-hydroperoxy-5,8,11,13-eicosatetraenoic acid; D006162:Guanylate Cyclase