Heme-dependent activation of soluble guanylate cyclase by nitric oxide: regulation of enzyme activity by porphyrins and metalloporphyrins.
Ignarro
L J
LJ
Department of Pharmacology, University of California School of Medicine, Los Angeles 90024.
D000818:Animals; D004789:Enzyme Activation; D006162:Guanylate Cyclase / Q000502:physiology*; D006418:Heme / Q000502:physiology*; D006801:Humans; D008665:Metalloporphyrins / Q000502:physiology*; D009569:Nitric Oxide / Q000494:pharmacology*; D011166:Porphyrins / Q000502:physiology*
D008665:Metalloporphyrins; D011166:Porphyrins; D009569:Nitric Oxide; D006418:Heme; D006162:Guanylate Cyclase