Reversible anorexia and rapid weight loss associated with neuroleptic administration in Alzheimer's disease.
Weight loss and malnutrition despite adequate dietary intake has been reported to be part of the clinical course in advanced dementia of the Alzheimer type. We present a case of reversible weight loss associated with neuroleptic use in a patient with Alzheimer's disease and discuss a possible pathophysiological basis for the weight loss.
Rohrbaugh
R M
RM
Department of Psychiatry, Yale University, New Haven, Connecticut.
Siegal
A P
AP
D000368:Aged; D000544:Alzheimer Disease / Q000188:drug therapy*; D000855:Anorexia / Q000139:chemically induced*; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D004334:Drug Administration Schedule; D004409:Dyskinesia, Drug-Induced / Q000209:etiology; D001068:Feeding and Eating Disorders / Q000139:chemically induced*; D005260:Female; D005476:Fluphenazine / Q000009:adverse effects; D006220:Haloperidol / Q000009:adverse effects; D006801:Humans; D010546:Perphenazine / Q000009:adverse effects; D015431:Weight Loss / Q000187:drug effects*
D014150:Antipsychotic Agents; D010546:Perphenazine; D006220:Haloperidol; D005476:Fluphenazine