[Quantifying functional deficits in patients with multiple sclerosis using a computer-assisted visuomotor tracking procedure].
23 Patients with multiple sclerosis were subjected to a visuomotor tracking test, consisting of subtests of different task difficulty, while being in a state of acute exacerbation and four weeks later, while exhibiting a more or less pronounced clinical remission (Kurtzke DSS 3.9 (+/- 1.4) vs. 3.3 (+/- 1.5); p less than 0.001). Corresponding to this the tracking test performances improved, the difference being significant only with the easiest test run. The tracking performances correlated with the Kurtzke scores, both for the acute state and for the remitted state, the highest correlation showing up for the easiest test run. Hence, the visuomotor tracking test seems to be suited to measure functional deficits and to evaluate the efficiency of therapeutic procedures.
Bräu
H
H
Abteilung für Neurologie, Freien Universität Berlin.
Ulrich
G
G
Kriebitzsch
R
R
Baum
K
K
D000324:Adrenocorticotropic Hormone / Q000627:therapeutic use*; D000328:Adult; D004185:Disability Evaluation; D005133:Eye Movements / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000188:drug therapy*; D011597:Psychomotor Performance / Q000187:drug effects*; D011698:Pursuit, Smooth / Q000187:drug effects*; D011930:Reaction Time / Q000187:drug effects
D000324:Adrenocorticotropic Hormone
Quantifizierung von Funktionsdefiziten bei Patienten mit multipler Sklerose mittels eines rechnergestützten visuomotorischen Tracking-Verfahrens.