title: Spontaneous and nerve-evoked quantal transmission in regenerated motor terminals.
abstract: Quantal acetylcholine release was studied in sciatic nerve-extensor digitorum longus muscle preparations from normal rats and in reinnervated muscles at different times following peroneus nerve crush. The efficiency of nerve-evoked transmission was regained almost completely at a time (20 days after crush) when the secretory response to increased extracellular K+ was very weak. This suggests that K+-induced secretion might be activated through mechanisms at least partially different from those involved in the response to nerve stimulation.
authors.affiliation: Department of Peripheral Nervous System Research, Fidia Research Laboratories, Abano Terme, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Di Gregorio
authors.forename: R
authors.initials: R
authors.lastname: Fesce
authors.forename: S
authors.initials: S
authors.lastname: Cereser
authors.forename: G
authors.initials: G
authors.lastname: Favaro
authors.forename: M G
authors.initials: MG
authors.lastname: Fiori
mesh_terms: D000818:Animals; D002799:Cholinergic Fibers / Q000378:metabolism / Q000502:physiology*; D003964:Diaphragm / Q000294:innervation; D009046:Motor Neurons / Q000378:metabolism / Q000502:physiology*; D009416:Nerve Regeneration; D012584:Sciatic Nerve / Q000378:metabolism / Q000502:physiology; D009435:Synaptic Transmission