title: [Parathyroid insufficiency syndrome. Two new cases: type Ia pseudohypoparathyroidism and pseudo-idiopathic hypoparathyroidism].
abstract: Two new cases with parathyroid insufficiency syndrome are described. The first one is a seven year and 6 months old male with Pseudohypoparathyroidism Type Ia, who has presented: hypocalcemia, hyperphoforemia, increased PTH and TSH, prolactin decreased and Albright hereditary osteodystrophy phenotype. The second one in a six year and four months old female with Pseudo-idiopathic hypoparathyroidism who has presented: hypocalcemia, hyperphosforemia, increased PTH, without any hormonal disturbances nor dysmorphias. Ellsworth-Howard test with 50 micrograms of 1-34 hPTH is made in both, remarking the different renal response about phosphaturia and plasmatic, urinary and nephrogenic cyclic AMP. The treatment is performed in both with calcitriol and oral calcium (L-Thyroxine is associated for the first patient). Biochemical disturbances are normalized. Other parathyroid insufficiency syndrome are revised.
authors.affiliation: Departamento de Pediatría, Hospital Maternoinfantil, Granada.
authors.forename: D
authors.initials: D
authors.lastname: Barajas de Frutos
authors.forename: J
authors.initials: J
authors.lastname: Pedrero Vera
authors.forename: J E
authors.initials: JE
authors.lastname: Bolívar Barrales
authors.forename: R
authors.initials: R
authors.lastname: Espigares Martín
authors.forename: L
authors.initials: L
authors.lastname: Ortega Martos
authors.forename: R
authors.initials: R
authors.lastname: Vílchez Joya
authors.forename: V
authors.initials: V
authors.lastname: Bolívar Galiano
authors.forename: J J
authors.initials: JJ
authors.lastname: Morell Bernabé
mesh_terms: D002117:Calcitriol / Q000627:therapeutic use; D002118:Calcium / Q000627:therapeutic use; D002648:Child; D000242:Cyclic AMP / Q000097:blood / Q000652:urine; D005260:Female; D006801:Humans; D006996:Hypocalcemia / Q000175:diagnosis; D007011:Hypoparathyroidism / Q000188:drug therapy / Q000209:etiology / Q000378:metabolism*; D008297:Male; D010281:Parathyroid Hormone / Q000097:blood; D011547:Pseudohypoparathyroidism / Q000188:drug therapy / Q000378:metabolism*; D013974:Thyroxine / Q000627:therapeutic use
chemical_list: D010281:Parathyroid Hormone; D000242:Cyclic AMP; D002117:Calcitriol; D013974:Thyroxine; D002118:Calcium
vernacular_title: Síndrome de insuficiencia paratiroidea. Dos nuevos casos: pseudohipoparatiroidismo tipo Ia e hipoparatiroidismo pseudoidiopático.