Acitretin monotherapy in acrodermatitis continua Hallopeau.
In a patient affected with acrodermatitis continua Hallopeau, acitretin (Ro 10-1670) monotherapy resulted in a complete clearance of pustulation at a dosage of 45 mg per day. At this dosage the leukotriene B4-induced intraepidermal accumulation of polymorphonuclear leukocytes was markedly inhibited.
van Dooren-Greebe
R J
RJ
Department of Dermatology, University of Nijmegen, The Netherlands.
van de Kerkhof
P C
PC
Chang
A
A
Happle
R
R
D017255:Acitretin; D000169:Acrodermatitis / Q000188:drug therapy* / Q000473:pathology; D000368:Aged; D002465:Cell Movement; D005385:Fingers; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000473:pathology; D014212:Tretinoin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use
D014212:Tretinoin; D017255:Acitretin