Malignant fibrous histiocytoma of sternum: an unusual cause of pyrexia of undetermined origin.
Malignant fibrous histiocytoma of the bone is a very rare tumour mainly affecting long bones, and the most common presenting symptom is local pain. A case of malignant fibrous histiocytoma presenting with pyrexia of undetermined origin and arising in the sternum, a localization not previously described, is reported. The patient died with septic shock after multi-drug chemotherapy including high dose methotrexate treatment with citrovorum factor rescue.
Grieco
A
A
Istituto di Clinica Medica Generale e Terapia Medica, Università Cattolica del Sacro Cuore, Rome, Italy.
Caputo
S
S
Silvestri
E
E
Caradonna
P
P
Bertoli
A
A
Greco
A V
AV
D000328:Adult; D001859:Bone Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D003937:Diagnosis, Differential; D005334:Fever / Q000209:etiology*; D018219:Histiocytoma, Benign Fibrous / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008297:Male; D013249:Sternum