Monoamine- and diamine oxidase activities in psoriasis.
Monoamine- and diamine oxidase activities were measured by a sensitive photometric assay in 25 psoriasis vulgaris patients. Results were compared with plasma histamine values determined fluorimetrically. Increased plasma histamine levels were associated with significantly lowered diamine--and type B monoamine oxidase activities in platelet-rich plasma of the psoriasis patients. Our data suggest that cofactor levels and/or inhibiting factors are responsible for the observed monoamine- and diamine oxidase activities.
Ionescu
G
G
Research Department, Spezialklinik Neukirchen, West Germany.
Kiehl
R
R
D000293:Adolescent; D000328:Adult; D006631:Amine Oxidase (Copper-Containing) / Q000097:blood*; D006632:Histamine / Q000097:blood; D006801:Humans; D008995:Monoamine Oxidase / Q000097:blood*; D011565:Psoriasis / Q000201:enzymology*
D006632:Histamine; D006631:Amine Oxidase (Copper-Containing); D008995:Monoamine Oxidase