[The immune structure of the population of the Bashkir ASSR in connection with hemorrhagic fever with renal syndrome and the relation of indices of collective immunity to morbidity and the nature of the landscape].
The study of 9,176 serum samples obtained from all regions and 15 cities of Bashkiria, carried out by the method of radioimmunoassay with the use of the antigen of hemorrhagic fever with the renal syndrome (HFRS), has revealed considerable differences in the size of the natural immune stratum of the population (43.9-0.8%). The size of such immune stratum characterizes the activity of natural foci: the largest immune stratum (25.4%) exists among the population of regions with broad-leaved forests, this stratum is somewhat less (12.2-13.2%) in regions with combined coniferous and broad-leaved forest, in regions with different combinations of broad-leaved forests and steppes, as well as mountain forests. On the Aĭsko-Kungurskaia forest-steppe territory and in regions characterized by a combination of steppe areas with mountain forests the immune stratum has been found to be even lesser (7.3-8.4%). The least immune stratum (3.4%) exists in steppe regions. By comparing the percentage of the population immune to HFRS and having had the diagnosis of HFRS over the period of 30 years the quality of the clinical diagnosis of this infection on the given territory may be determined.
Miasnikov
Iu A
IuA
Tkachenko
E A
EA
Rezankin
G V
GV
Stepanenko
A G
AG
Kireev
S G
SG
D000914:Antibodies, Viral / Q000032:analysis; D001486:Bashkiria; D005843:Geography; D006476:Orthohantavirus / Q000276:immunology; D006480:Hemorrhagic Fever with Renal Syndrome / Q000453:epidemiology / Q000276:immunology*; D006801:Humans; D007113:Immunity, Innate / Q000276:immunology; D011159:Population Surveillance; D012424:Rural Population; D014505:Urban Population
D000914:Antibodies, Viral
Immunnaia struktura naseleniia Bashkirskoĭ ASSR v otnoshenii gemorragicheskoĭ likhoradki s pochechnym sindromom i sviaz' pokazateleĭ kollektivnogo immuniteta s zabolevaemost'iu i kharakterom landshafta.