Direct detection of radical production in the ischaemic and reperfused myocardium: current status.
Electron spin resonance (e.s.r.) spectroscopy, which is a specific method for directly detecting free radicals in biological systems, has now been used in a number of studies to examine free radical generation in both ischaemic and reperfused myocardial tissue. This review critically assesses the information which has been obtained to date with particular reference to the elucidation of the nature and source of the radicals observed in these studies.
Davies
M J
MJ
Department of Chemistry, University of York, U.K.
D000818:Animals; D003327:Coronary Disease / Q000378:metabolism*; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals; D005615:Freezing; D015425:Myocardial Reperfusion; D009206:Myocardium / Q000378:metabolism*
D005609:Free Radicals