Narcotic analgesics and debrisoquine polymorphism.
Lavrijsen
K L
KL
Heykants
J J
JJ
D000701:Analgesics, Opioid / Q000493:pharmacokinetics*; D019389:Cytochrome P-450 CYP2D6; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D003647:Debrisoquin / Q000493:pharmacokinetics*; D006801:Humans; D066298:In Vitro Techniques; D007546:Isoquinolines / Q000493:pharmacokinetics*; D008862:Microsomes, Liver / Q000201:enzymology; D006899:Mixed Function Oxygenases / Q000378:metabolism; D011110:Polymorphism, Genetic / Q000187:drug effects*
D000701:Analgesics, Opioid; D007546:Isoquinolines; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D019389:Cytochrome P-450 CYP2D6; D003647:Debrisoquin