title: Treatment of right-sided Staphylococcus aureus endocarditis in intravenous drug users with ciprofloxacin and rifampicin.
abstract: A combination of ciprofloxacin (intravenous then oral) and oral rifampicin was tested in 14 intravenous drug users with right-sided Staphylococcus aureus endocarditis. All 10 patients who completed therapy were cured based on resolution of symptoms and negative blood cultures at 4 weeks post therapy.
authors.affiliation: Department of Medicine, University of California, San Francisco.
authors.forename: R J
authors.initials: RJ
authors.lastname: Dworkin
authors.forename: B L
authors.initials: BL
authors.lastname: Lee
authors.forename: M A
authors.initials: MA
authors.lastname: Sande
authors.forename: H F
authors.initials: HF
authors.lastname: Chambers
mesh_terms: D000328:Adult; D002939:Ciprofloxacin / Q000008:administration & dosage / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D004452:Echocardiography; D004697:Endocarditis, Bacterial / Q000188:drug therapy* / Q000209:etiology / Q000382:microbiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010865:Pilot Projects; D012293:Rifampin / Q000008:administration & dosage / Q000627:therapeutic use*; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000209:etiology / Q000382:microbiology; D015819:Substance Abuse, Intravenous / Q000150:complications*
chemical_list: D002939:Ciprofloxacin; D012293:Rifampin