Low density lipoprotein binding by macroporous bead cellulose.
Cellulose of a certain macroporous structure is capable of binding selectively low density lipoproteins (LDL) whilst maintaining high density lipoprotein (HDL) levels. It was ascertained that the porous structure of the cellulose causes binding of LDL and that also diffusion processes play a role. To a certain extent special bindings such as hydrogen bonds between cellulose and LDL and/or hydrophobic interactions may furthermore be of importance for the LDL fixation.
Behm
E
E
Department of Internal Medicine, Wilhelm Pieck University, Rostock, GDR.
Loth
F
F
Toewe
D
D
Zschörnig
O
O
Ernst
B
B
Klinkmann
H
H
D000327:Adsorption; D002482:Cellulose; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D004578:Electron Spin Resonance Spectroscopy; D006801:Humans; D006860:Hydrogen Bonding; D007700:Kinetics; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood*; D011485:Protein Binding; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D014280:Triglycerides; D002482:Cellulose