Sertraline potently displaces (+)-[3H]3-PPP binding to sigma sites in rat brain.
Schmidt
A
A
Department of Neuroscience, Pfizer Inc., Groton, CT 06340.
Lebel
L
L
Koe
B K
BK
Seeger
T
T
Heym
J
J
D015057:1-Naphthylamine / Q000031:analogs & derivatives / Q000494:pharmacology*; D000818:Animals; D001667:Binding, Competitive / Q000187:drug effects; D001923:Brain Chemistry / Q000187:drug effects*; D066298:In Vitro Techniques; D009281:Naphthalenes / Q000494:pharmacology*; D010880:Piperidines / Q000378:metabolism*; D051381:Rats; D011957:Receptors, Opioid / Q000378:metabolism*; D017465:Receptors, Opioid, delta; D012702:Serotonin Antagonists / Q000494:pharmacology*; D020280:Sertraline
D009281:Naphthalenes; D010880:Piperidines; D011957:Receptors, Opioid; D017465:Receptors, Opioid, delta; D012702:Serotonin Antagonists; D015057:1-Naphthylamine; C026539:preclamol; D020280:Sertraline