Long-term response in a patient with ITP following low dose anti-D immunoglobulin therapy.
A patient with chronic ITP relapsed after conventional therapy but following an infusion with low dose anti D (Rho) immunoglobulin, she entered a remission which has now lasted 10 months. This is difficult to explain on the basis of long term macrophage Fc receptor blockade and suggests an alternative mechanism of action.
Smith
N A
NA
Department of Haematology, Queen Elizabeth Hospital, Edgbaston, Birmingham.
Chakraverty
R K
RK
Obeid
D
D
Boughton
B J
BJ
D001792:Blood Platelets / Q000276:immunology; D002648:Child; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000008:administration & dosage*; D008264:Macrophages / Q000276:immunology; D011696:Purpura, Thrombocytopenic / Q000097:blood / Q000276:immunology / Q000628:therapy*; D011961:Receptors, Fc; D012204:Rh-Hr Blood-Group System; D018029:Rho(D) Immune Globulin
D007136:Immunoglobulins; D011961:Receptors, Fc; D012204:Rh-Hr Blood-Group System; D018029:Rho(D) Immune Globulin