title: [A comparative evaluation of the level of sphingomyelinase activity in liver cell nuclei and in the brain].
abstract: It was discovered that there is sphingomyelinase activity in the rat liver nuclei. The maximum of enzyme activity is at pH 7.1. The data obtained demonstrated that the main part of sphingomyelinase is located in the nuclear membrane. Comparison of sphingomyelinase activity in cell nuclei, liver and brain homogenates shows high level of enzyme activity in the nuclei. The authors discuss possible participation of sphingomyelinases in changes of phospholipids composition in nuclear structure under different functional activity of cell nuclei.
authors.forename: A V
authors.initials: AV
authors.lastname: Alesenko
authors.forename: N A
authors.initials: NA
authors.lastname: Babenko
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Pushkareva
authors.forename: V N
authors.initials: VN
authors.lastname: Nikitin
mesh_terms: D000818:Animals; D001921:Brain / Q000201:enzymology*; D002467:Cell Nucleus / Q000201:enzymology*; D006863:Hydrogen-Ion Concentration; D008099:Liver / Q000201:enzymology*; D008297:Male; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism*; D051381:Rats; D013108:Sphingomyelin Phosphodiesterase / Q000032:analysis / Q000378:metabolism*
chemical_list: D010727:Phosphoric Diester Hydrolases; D013108:Sphingomyelin Phosphodiesterase
vernacular_title: Sravnitel'naia otsenka urovnia sfingomielinaznoĭ aktivnosti v iadrakh kletok pecheni i v mozge.