Transient acantholytic dermatosis associated with lymphomatous angioimmunoblastic lymphadenopathy.
Transient acantholytic dermatosis is a papulovesicular cutaneous eruption first described in 1970. There have been subsequent reports of similar disorders occurring in patients with malignancy. Angioimmunoblastic lymphadenopathy with dysproteinemia is a disorder characterized by an acute onset of generalized lymphadenopathy associated with fever, malaise, pruritus, night sweats, and hepatosplenomegaly. The patient described had a papular acantholytic dermatosis associated with the development of angioimmunoblastic lymphadenopathy with dysproteinemia-like T-cell lymphoma. The cutaneous manifestations of angioimmunoblastic lymphadenopathy with dysproteinemia are discussed.
Zelickson
B D
BD
Department of Dermatology, Mayo Clinic Rochester, Minnesota 55905.
Tefferi
A
A
Gertz
M A
MA
Banks
P M
PM
Pittelkow
M R
MR
D000051:Acantholysis / Q000150:complications* / Q000473:pathology; D000368:Aged; D005260:Female; D006801:Humans; D007119:Immunoblastic Lymphadenopathy / Q000150:complications* / Q000473:pathology; D008223:Lymphoma / Q000150:complications* / Q000473:pathology; D012871:Skin Diseases / Q000150:complications*; D013601:T-Lymphocytes