The use of flumazenil (Anexate, Ro 15-1788) in the management of drug overdose.
This is a report of a large selfadministered overdose of temazepam and meprobamate. The administration of flumazenil (Ro 15-1788) led to the partial antagonism of the depressant action of the drugs which was sufficient to avoid the need for invasive respiratory and cardiovascular support.
Pollard
B J
BJ
Department of Anaesthesia, Manchester Royal Infirmary.
Masters
A P
AP
Bunting
P
P
D014151:Anti-Anxiety Agents / Q000506:poisoning*; D005442:Flumazenil / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008620:Meprobamate / Q000506:poisoning*; D008875:Middle Aged; D013693:Temazepam / Q000506:poisoning*
D014151:Anti-Anxiety Agents; D005442:Flumazenil; D008620:Meprobamate; D013693:Temazepam