[The action of strontium and barium ions on the calcium binding and transport systems of nerve cells].
Using Ca-sensitive fluorescent probe (fura-2) Sr and Ba absorption by intracellular organelles after cell loading by these cations and their effect on Ca release from intracellular stores were studied on isolated snail neurons. It was shown that Sr could effectively replace intracellular Ca, whereas Ba ions are not absorbed inside the cell and block a Ca-induced Ca release from intracellular stores.
Usachev
Iu M
IuM
Mironov
S L
SL
D000042:Absorption; D000818:Animals; D001464:Barium / Q000493:pharmacokinetics / Q000494:pharmacology*; D001572:Benzofurans; D001692:Biological Transport / Q000187:drug effects / Q000502:physiology; D002118:Calcium / Q000378:metabolism*; D015220:Calcium Channels / Q000187:drug effects / Q000378:metabolism; D016257:Fura-2; D066298:In Vitro Techniques; D007477:Ions; D009474:Neurons / Q000187:drug effects* / Q000378:metabolism; D012908:Snails; D013324:Strontium / Q000493:pharmacokinetics / Q000494:pharmacology*
D001572:Benzofurans; D015220:Calcium Channels; D007477:Ions; D001464:Barium; D002118:Calcium; D016257:Fura-2; D013324:Strontium
Deĭstvie ionov strontsiia i bariia na sistemy sviazyvaniia i transporta kal'tsiia v nervnykh kletkakh.