[The evaluation and choice of treatment methods (surgical removal, proton-beam irradiation) in endosellar hypophyseal adenomas].
The article analyses the immediate and late-term results of treatment of endosellar pituitary adenomas: removal through a transsphenoidal approach--16 patients, transnasal stereotaxic administration of 90Y--14 patients, irradiation by proton beam--263 patients. Surgery as well as radiotherapy produced quite satisfactory results. Proton therapy on a Leningrad synchrocyclotron is not inferior to the modern surgical methods in efficacy and safety. It is indicated in endosellar pituitary adenomas when the sella turcica measures no more than 20 x 16 mm.
Mel'kishev
V F
VF
Konnov
B A
BA
Tigliev
G S
GS
Mel'nikovLA
Kamalova
G M
GM
D000236:Adenoma / Q000150:complications / Q000628:therapy*; D006801:Humans; D007016:Hypophysectomy; D010315:Particle Accelerators; D010910:Pituitary Irradiation; D010911:Pituitary Neoplasms / Q000150:complications / Q000628:therapy*; D011522:Protons; D011878:Radiotherapy / Q000009:adverse effects; D011879:Radiotherapy Dosage; D012658:Sella Turcica; D015021:Yttrium Radioisotopes / Q000627:therapeutic use
D011522:Protons; D015021:Yttrium Radioisotopes
Otsenka i vybor metodov lecheniia (khirurgicheskoe udalenie, obluchenie puchkom protonov) éndoselliarnykh adenom gipofiza.