title: Somatostatin treatment of gastrointestinal fistulae.
abstract: Output from gastrointestinal fistulae to the skin was measured in five patients during total parenteral nutrition and restricted oral intake. Supplemental infusion of somatostatin during six days caused a significant reduction in discharge in all patients compared to the pretreatment level, but none of the fistulae closed as a result of the treatment. Somatostatin may be considered an adjuvant drug to parenteral nutrition and restricted oral intake in the conservative treatment of external fistulae from the gastrointestinal tract.
authors.affiliation: Department of Medical Gastroenterology P, Rigshospitalet, University of Copenhagen, Denmark.
authors.forename: C
authors.initials: C
authors.lastname: Palnaes Hansen
authors.forename: J
authors.initials: J
authors.lastname: Hegnhøj
authors.forename: O
authors.initials: O
authors.lastname: Olsen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004378:Duodenal Diseases / Q000188:drug therapy / Q000628:therapy; D005402:Fistula / Q000188:drug therapy* / Q000628:therapy; D006801:Humans; D007412:Intestinal Fistula / Q000188:drug therapy* / Q000628:therapy; D007579:Jejunal Diseases / Q000188:drug therapy / Q000628:therapy; D008875:Middle Aged; D010185:Pancreatic Fistula / Q000188:drug therapy / Q000628:therapy; D010289:Parenteral Nutrition, Total; D012871:Skin Diseases / Q000188:drug therapy* / Q000628:therapy; D013004:Somatostatin / Q000627:therapeutic use*
chemical_list: D013004:Somatostatin