Determination of Arduan and its desacetyl metabolites in biological fluids.
The authors elaborated a method for the determination of Arduan and its desacetyl metabolites in biological fluids. The method is based on the use of labelled Arduan and on the determination of radioactivity of the parent drug and metabolites separated by ion-pair TLC in the development system of chloroform-dichloromethane-methanol 6 : 2 : 2 (v/v) 3% NaI (w/v).
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D015113:Androstane-3,17-diol / Q000031:analogs & derivatives / Q000032:analysis* / Q000097:blood / Q000652:urine; D000732:Androstanols / Q000032:analysis*; D001646:Bile / Q000032:analysis; D001711:Biotransformation; D002855:Chromatography, Thin Layer / Q000379:methods; D006801:Humans; D009466:Neuromuscular Blocking Agents / Q000032:analysis*; D017300:Pipecuronium; D010879:Piperazines / Q000032:analysis* / Q000097:blood / Q000652:urine
D000732:Androstanols; D009466:Neuromuscular Blocking Agents; D010879:Piperazines; D017300:Pipecuronium; D015113:Androstane-3,17-diol