title: Malignant fibrous histiocytoma of sternum: an unusual cause of pyrexia of undetermined origin.
abstract: Malignant fibrous histiocytoma of the bone is a very rare tumour mainly affecting long bones, and the most common presenting symptom is local pain. A case of malignant fibrous histiocytoma presenting with pyrexia of undetermined origin and arising in the sternum, a localization not previously described, is reported. The patient died with septic shock after multi-drug chemotherapy including high dose methotrexate treatment with citrovorum factor rescue.
authors.affiliation: Istituto di Clinica Medica Generale e Terapia Medica, Università Cattolica del Sacro Cuore, Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Grieco
authors.forename: S
authors.initials: S
authors.lastname: Caputo
authors.forename: E
authors.initials: E
authors.lastname: Silvestri
authors.forename: P
authors.initials: P
authors.lastname: Caradonna
authors.forename: A
authors.initials: A
authors.lastname: Bertoli
authors.forename: A V
authors.initials: AV
authors.lastname: Greco
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D003937:Diagnosis, Differential; D005334:Fever / Q000209:etiology*; D018219:Histiocytoma, Benign Fibrous / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008297:Male; D013249:Sternum