A biochemical approach to essential hypertension.
Using multivariate statistical analysis, an attempt has been made to select hypertensive and normotensive sub-groups of subjects on the basis of certain parameters of their blood serum, such as the inhibition of purified Na,K-ATPase by serum and the content of two proteins with molecular masses of 12 and 15 kDa. An analysis of 20 human beings (10 hypertensive and 10 normotensive individuals) revealed that the best division into sub-groups is achieved only through the use of a combination of these three parameters.
Rogaeva
E A
EA
All-Union Cardiology Research Center, USSR Academy of Medical Sciences, Moscow.
Boldyrev
A A
AA
Lopina
O D
OD
Rubtsov
A M
AM
Perova
N V
NV
Zhigareva
N N
NN
Oganov
R G
RG
D000293:Adolescent; D000328:Adult; D001798:Blood Proteins / Q000032:analysis*; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000175:diagnosis*; D008875:Middle Aged; D008970:Molecular Weight; D011336:Probability; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors*
D001798:Blood Proteins; D000254:Sodium-Potassium-Exchanging ATPase