title: The histochemical location of three diagnostic enzymes in the marmoset liver.
abstract: The histochemical locations of alkaline phosphate (ALP), leucine aminopeptidase (LAP) and gamma glutamyltransferase (GGT) were demonstrated in the liver of the marmoset (Callithrix jacchus). Although all three enzymes were located in cell membranes, the location of LAP was demonstrated by a chromogenic substrate, in the canalicular membrane. GGT was seen in a vascular network, provisionally identified as the peribiliary arterial plexus. Possible diagnostic applications in toxicology are discussed.
authors.affiliation: Roche Products Ltd., Herts, UK.
authors.forename: C W
authors.initials: CW
authors.lastname: Davy
authors.forename: M
authors.initials: M
authors.lastname: Fulleylove
authors.forename: J
authors.initials: J
authors.lastname: Edmunds
authors.forename: D
authors.initials: D
authors.lastname: Allsop
authors.forename: D A
authors.initials: DA
authors.lastname: Eichler
authors.forename: B
authors.initials: B
authors.lastname: Rushton
authors.forename: J M
authors.initials: JM
authors.lastname: Walker
mesh_terms: D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D002143:Callitrichinae / Q000378:metabolism*; D006651:Histocytochemistry; D007931:Leucyl Aminopeptidase / Q000378:metabolism; D008099:Liver / Q000201:enzymology*; D005723:gamma-Glutamyltransferase / Q000378:metabolism
chemical_list: D005723:gamma-Glutamyltransferase; D000469:Alkaline Phosphatase; D007931:Leucyl Aminopeptidase