Glycemia in the post-resuscitation period. The Cerebral Resuscitation Study Group.
An association between high glycemia on admission after resuscitation from an out-of-hospital cardiac arrest and poor neurological recovery has been reported. It remains controversial whether the high glycemia on admission causes the poor outcome or is just an epiphenomenon. The Cerebral Resuscitation Study Group therefore registered the glycemia on admission in 417 patients resuscitated after an out-of-hospital cardiac arrest. Our data confirm that a high glycemia on admission is related to a poor outcome. There is no relationship between the glycemia on admission and the duration of cardiopulmonary resuscitation (CPR). However, there is a positive but weak correlation between the dose of adrenaline administered during CPR and the glycemia on admission. This indicates that the higher glycemia on admission in patients with a poor outcome may, at least in part, be due to CPR parameters, such as the amount of adrenaline used, that are linked with a bad prognosis. However, it cannot be excluded that a high glycemia contributes to the brain damage after cardiac arrest.
Calle
P A
PA
Heymans Institute of Pharmacology, University Hospital of Gent, Belgium.
Buylaert
W A
WA
Vanhaute
O A
OA
D001786:Blood Glucose / Q000032:analysis*; D004305:Dose-Response Relationship, Drug; D004837:Epinephrine / Q000008:administration & dosage / Q000627:therapeutic use; D006323:Heart Arrest / Q000097:blood / Q000628:therapy*; D006760:Hospitalization; D006801:Humans; D011237:Predictive Value of Tests; D012151:Resuscitation
D001786:Blood Glucose; D004837:Epinephrine