title: Evaluation of a mouse Y chromosome probe for assessing marrow transplantation.
abstract: The multicopy mouse Y chromosome DNA probe 80Y/B (1) has been used to probe genomic DNA isolated from male and female bone marrow cells, mixed together in known ratios. It was found that in a mixture with a ratio of 1 male:200 female marrow cells the male cells could readily be detected by this method. The potential use of this technique for assessing repopulation kinetics of marrow transplantation is discussed.
authors.affiliation: Department of Experimental Haematology, Paterson Institute for Cancer Research, Manchester, England.
authors.forename: I N
authors.initials: IN
authors.lastname: Hampson
authors.forename: E
authors.initials: E
authors.lastname: Spooncer
authors.forename: T M
authors.initials: TM
authors.lastname: Dexter
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000032:analysis; D016026:Bone Marrow Transplantation; D002678:Chimera; D015342:DNA Probes; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000032:analysis; D008297:Male; D051379:Mice; D009693:Nucleic Acid Hybridization; D014998:Y Chromosome
chemical_list: D015342:DNA Probes