title: A cytotoxic human-human hybridoma antibody (TrC7) specific for HLA-A29.
abstract: TrC7 is a cytotoxic IgM human-human hybridoma anti-HLA Ab. Its reaction pattern with a panel of 48 HLA-typed EBV-transformed cell lines and PBMC from 348 HLA-typed individuals correlated precisely with expression of HLA-A29. TrC7 did not react with HLA-A30, -31, -32 or -w33, which, like A29, are splits of Aw19.
authors.affiliation: Institute of Medical Biology, University of Tromsø, School of Medicine, Norway.
authors.forename: A
authors.initials: A
authors.lastname: Kolstad
authors.forename: A
authors.initials: A
authors.lastname: Bratlie
authors.forename: K
authors.initials: K
authors.lastname: Hannestad
mesh_terms: D000911:Antibodies, Monoclonal / Q000276:immunology*; D000918:Antibody Specificity; D000920:Antibody-Dependent Cell Cytotoxicity; D002461:Cell Line, Transformed; D004797:Enzyme-Linked Immunosorbent Assay; D015234:HLA-A Antigens / Q000276:immunology*; D004854:Herpesvirus 4, Human; D006801:Humans; D006825:Hybridomas / Q000276:immunology*; D012397:Rosette Formation
chemical_list: D000911:Antibodies, Monoclonal; D015234:HLA-A Antigens; C035524:HLA-A29 antigen