title: [The hypothalamus-hypophysis-adrenal system in patients with lactorrhea-amenorrhea syndrome].
abstract: Function of the hypothalamo-hypophyseal-adrenal system was investigated in 23 patients with different types of the lactorrhea-amenorrhea syndrome. The basal levels and "stress secretion" of ACTH, cortisol and cyclic nucleotides, the circadian rhythm of ACTH and cortisol levels were determined by RIA. Noticeable disorders in the central and peripheral factors of this system and changes in the blood levels of cyclic nucleotides were observed in patients with the lactorrhea-amenorrhea syndrome.
authors.forename: V A
authors.initials: VA
authors.lastname: Oleĭnik
authors.forename: E V
authors.initials: EV
authors.lastname: Luchitskiĭ
authors.forename: G V
authors.initials: GV
authors.lastname: Valueva
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D000568:Amenorrhea / Q000097:blood / Q000503:physiopathology*; D005260:Female; D005687:Galactorrhea / Q000097:blood / Q000503:physiopathology*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects / Q000503:physiopathology*; D007328:Insulin; D007775:Lactation Disorders / Q000503:physiopathology*; D008787:Metoclopramide; D008875:Middle Aged; D009712:Nucleotides, Cyclic / Q000097:blood; D010913:Pituitary-Adrenal System / Q000187:drug effects / Q000503:physiopathology*; D011388:Prolactin / Q000097:blood; D013577:Syndrome; D013973:Thyrotropin-Releasing Hormone; D013997:Time Factors
chemical_list: D007328:Insulin; D009712:Nucleotides, Cyclic; D013973:Thyrotropin-Releasing Hormone; D000324:Adrenocorticotropic Hormone; D011388:Prolactin; D008787:Metoclopramide; D006854:Hydrocortisone
vernacular_title: Sistema gipotalamus-gipofiz-nadpochechniki u bol'nykh s sindromom ffktorei-amenorei.