Absence of murine melanoma 5'-nucleotidase activity is not attributable to a detectable inhibitor.
Previous observations indicated the absence of demonstrable 5'-nucleotidase activity in six of seven cultured murine melanoma cell lines. It could not be determined from those studies whether the enzyme was absent, or whether an inhibitor was present. The current studies indicate that no inhibitor can be demonstrated, therefore the enzyme is absent.
Moody
D
D
Department of Pathology, Georgetown University Medical Center, Washington, D.C. 20007.
Bijwaard
K E
KE
Gersten
D M
DM
D015720:5'-Nucleotidase / Q000378:metabolism*; D000818:Animals; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D008546:Melanoma, Experimental / Q000201:enzymology* / Q000473:pathology; D051379:Mice; D014407:Tumor Cells, Cultured / Q000187:drug effects / Q000201:enzymology / Q000473:pathology
D004791:Enzyme Inhibitors; D015720:5'-Nucleotidase