title: [New color imaging of [99mTc]-pyrophosphate and [201Tl]-chloride dual isotope single photon emission computed tomography in acute myocarditis].
abstract: [99mTc]-pyrophosphate (PYP) and [201Tl]-chloride dual isotope single photon emission computed tomography (SPECT) is now available to detect the site and extent of acute myocardial infarction. In inflammatory myocardial disease, [99mTc]PYP makes hot image on damaged area. We performed dual isotope SPECT of [99mTc]PYP and [201Tl]Cl in two patients with acute myocarditis and severe rhythm disturbance to evaluate the severity of inflammation. Myocardial damage was estimated by [201Tl] perfusion coloring blue and myocardial inflammation was estimated by [99mTc]PYP uptake coloring red. The overlap display of both images made it clear to detect spatial extent of myocardial inflammation. Using this technique, we expect to estimate the severity of myocarditis and to make a decision of therapeutic plan.
authors.forename: K
authors.initials: K
authors.lastname: Kitahara
authors.forename: S
authors.initials: S
authors.lastname: Suzuki
authors.forename: Y
authors.initials: Y
authors.lastname: Takayama
authors.forename: M
authors.initials: M
authors.lastname: Hiroe
mesh_terms: D000208:Acute Disease; D000328:Adult; D011756:Diphosphates; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D009220:Myositis / Q000000981:diagnostic imaging*; D013667:Technetium; D016698:Technetium Tc 99m Pyrophosphate; D013793:Thallium; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*
chemical_list: D011756:Diphosphates; D013794:Thallium Radioisotopes; C027549:thallium chloride; D016698:Technetium Tc 99m Pyrophosphate; D013667:Technetium; D013793:Thallium