title: [Prolonged action of vecuronium in neurofibromatosis (von Recklinghausen's disease)].
abstract: It is reported on an abnormally prolonged action of vecuronium in a female patient with known neurofibromatosis (Morbus von Recklinghausen). In this female patient an increased sensitivity to vecuronium (0.06 mg/kg) was observed during anaesthesia for Caesarean section. A 100% block lasted 50 minutes and the neuromuscular recovery from 75% block to 25% block amounted to 25 minutes. This prolonged neuromuscular block can also be due to overdosing, relative hypovolaemia during arterial hypertension and the previous application of suxamethonium.
authors.forename: G
authors.initials: G
authors.lastname: Mitterschiffthaler
authors.forename: U
authors.initials: U
authors.lastname: Maurhard
authors.forename: O
authors.initials: O
authors.lastname: Huter
authors.forename: C
authors.initials: C
authors.lastname: Brezinka
mesh_terms: D000328:Adult; D000773:Anesthesia, Obstetrical; D002585:Cesarean Section; D005260:Female; D006801:Humans; D009456:Neurofibromatosis 1 / Q000503:physiopathology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*; D013997:Time Factors; D014673:Vecuronium Bromide / Q000494:pharmacology*
chemical_list: D014673:Vecuronium Bromide
vernacular_title: Verlängerte Wirkung von Vecuronium bei Neurofibromatose (Morbus von Recklinghausen).