Tissue-specific genes for respiratory proteins.
All but one of the mitochondrial respiratory complexes are composed of products of both the mitochondrial and the nuclear genomes. The recent isolation of cDNAs for several nuclear-encoded respiratory proteins reveals that some of them are present in at least two forms. Although some of these forms are traditional in differing somewhat in amino acid sequence, a new class, termed silent isoforms, differs in the presequence but contains identical processed proteins. What are the roles of tissue isoforms in oxidative metabolism?
Lomax
M I
MI
Grossman
L I
LI
D000818:Animals; D004272:DNA, Mitochondrial / Q000235:genetics; D003576:Electron Transport Complex IV / Q000235:genetics*; D005786:Gene Expression Regulation; D005796:Genes; D007527:Isoenzymes / Q000235:genetics; D008928:Mitochondria / Q000201:enzymology*
D004272:DNA, Mitochondrial; D007527:Isoenzymes; D003576:Electron Transport Complex IV