[Stereotaxic biopsy of intracranial processes: validity of histologic diagnosis].
The diagnostic validity of stereotactic intracranial biopsies was investigated in 70 patients retrospectively. In 56 cases (80%) the presence of a neoplastic lesion as well as its grade of malignancy was proved by cytological, histological and immunohistochemical techniques. An inflammatory or vascular lesion was found in 8 patients (11.4%). In 6 patients (8.6%) the nature of the lesion remained unclear because of nonspecific histological findings. In 27 cases a correlation was found between the biopsy specimens and corresponding material obtained during open surgery or autopsy. 24 concordant results were found (88.9%). In one case a malignant tumour was classified only according to the findings obtained at operation. In two cases subsequently diagnosed as glioblastoma biopsy reported a higher differentiated astrocytoma and a non-neoplastic lesion, respectively. These results confirm stereotactic biopsy of intracranial lesions as a method with low complication rate and high diagnostic validity.
Ungersböck
K
K
Neurochirurgische Universitätsklinik, Wien.
Schmidbauer
M
M
Budka
H
H
Kitz
K
K
Grunert
P
P
Koos
W
W
D001254:Astrocytoma / Q000473:pathology; D001706:Biopsy / Q000379:methods*; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000473:pathology; D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D005909:Glioblastoma / Q000473:pathology; D005910:Glioma / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D013238:Stereotaxic Techniques; D014057:Tomography, X-Ray Computed
Stereotaktische Biopsie intrakranieller Prozesse: Validität der histologischen Diagnostik.