[Contraction of skeletal muscles: regulation of calcium intracellular movements].
The different membrane systems and proteins involved in the control of intracellular calcium movements in the skeletal muscle cell are described. These include the sarcoplasmic reticulum, that Ca(++)-ATPase sarcoplasmic reticular calcium pump, transverse tubules, calcium channels, and the ryanodine receptor protein. The significance of these systems is shown clearly in the myopathies, where the main errors involved do not concern the contractile system, but the command and control mechanisms.
Villaz
M
M
Laboratoire de Biophysique Moléculaire et Cellulaire (URA520 du CNRS), LBIO-CENG, Grenoble.
Carrier
L
L
D002118:Calcium / Q000378:metabolism*; D015220:Calcium Channels / Q000378:metabolism*; D000252:Calcium-Transporting ATPases / Q000378:metabolism; D004095:Dihydropyridines; D006801:Humans; D009119:Muscle Contraction; D009132:Muscles / Q000166:cytology* / Q000378:metabolism; D009135:Muscular Diseases / Q000503:physiopathology; D009210:Myofibrils / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000302:isolation & purification; D012433:Ryanodine; D012519:Sarcoplasmic Reticulum / Q000378:metabolism
D015220:Calcium Channels; D004095:Dihydropyridines; D011956:Receptors, Cell Surface; D012433:Ryanodine; D000252:Calcium-Transporting ATPases; D002118:Calcium
Contraction du muscle squelettique: régulation des mouvements intracellulaires du calcium.