Neuroepithelial small cell carcinoma of the vagina.
We studied two patients with primary vaginal small cell carcinomas. Their tumors show histologic and ultrastructural neuroepithelial elements similar to those reported in the literature in the cervix and the lung. The clinical behavior of the tumors was aggressive in both patients. Ultrastructural study of small cell genital tract neoplasms is indicated to help classify this disease. Adjunctive therapy may be required for neoplasms of neuroepithelial origin.
Chafe
W
W
Division of Gynecology Oncology, University of Florida College of Medicine, Gainesville 32610.
D000368:Aged; D018288:Carcinoma, Small Cell / Q000473:pathology* / Q000628:therapy / Q000648:ultrastructure; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000473:pathology / Q000628:therapy / Q000648:ultrastructure; D014625:Vaginal Neoplasms / Q000473:pathology* / Q000628:therapy / Q000648:ultrastructure