title: [Enzymologic diagnosis of cerebral lesions in generalized forms of meningococcal infection in the acute period].
abstract: Cerebrospinal fluid was tested for several enzymes (CPK, AST, GGTP, BP, BG, AK) in 97 patients with generalized meningococcal infection with prevalent CNS affliction. Marked changes were detected even in the absence of clinical signs of cerebral lesion that was typical only of meningococcemia. Nevertheless, most pronounced changes were observed in a group of patients with cerebral edema and swelling. The changes in cerebrospinal fluid enzyme levels coincided with a reduced glucose and increased protein contents. In these cases, CSF hypertension increased CSF pressure to maximal levels. Most informative indices were singled out and their levels characteristic of acute phase of the disease established.
authors.forename: G G
authors.initials: GG
authors.lastname: Radzivil
authors.forename: I M
authors.initials: IM
authors.lastname: Roslyĭ
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000469:Alkaline Phosphatase / Q000134:cerebrospinal fluid; D001219:Aspartate Aminotransferases / Q000134:cerebrospinal fluid; D002555:Cerebrospinal Fluid / Q000201:enzymology*; D003402:Creatine Kinase / Q000134:cerebrospinal fluid; D004789:Enzyme Activation; D005260:Female; D005966:Glucuronidase / Q000134:cerebrospinal fluid; D006801:Humans; D006849:Hydrocephalus / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000209:etiology; D008297:Male; D008585:Meningitis, Meningococcal / Q000150:complications*; D008590:Meningoencephalitis / Q000150:complications*; D008875:Middle Aged; D005723:gamma-Glutamyltransferase / Q000134:cerebrospinal fluid
chemical_list: D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases; D003402:Creatine Kinase; D000469:Alkaline Phosphatase; D005966:Glucuronidase
vernacular_title: Enzimologicheskaia diagnostika porazheniĭ golovnogo mozga pri generalizovannykh formakh meningokokkovoĭ infektsii v ostrom periode zabolevaniia.