title: Clinical and laboratory findings implicating palytoxin as cause of ciguatera poisoning due to Decapterus macrosoma (mackerel).
abstract: A near fatal case of ciguatera-related intoxication following consumption of smoked Decapterus macrosoma is documented. In addition to some of the hallmark symptoms of ciguatera poisoning, the patient exhibited acute respiratory distress and severe muscle spasms. Laboratory results showed large elevations in a number of blood enzymes, indicative of muscle damage. The responsible agent was extracted from corresponding fish samples and identified as palytoxin.
authors.affiliation: School of Public Health, University of Hawaii, Honolulu.
authors.forename: A M
authors.initials: AM
authors.lastname: Kodama
authors.forename: Y
authors.initials: Y
authors.lastname: Hokama
authors.forename: T
authors.initials: T
authors.lastname: Yasumoto
authors.forename: M
authors.initials: M
authors.lastname: Fukui
authors.forename: S J
authors.initials: SJ
authors.lastname: Manea
authors.forename: N
authors.initials: N
authors.lastname: Sutherland
mesh_terms: D000178:Acrylamides; D000328:Adult; D000818:Animals; D036841:Ciguatera Poisoning; D002922:Ciguatoxins / Q000032:analysis; D003064:Cnidarian Venoms / Q000506:poisoning*; D005399:Fishes / Q000378:metabolism*; D005517:Foodborne Diseases / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008387:Marine Toxins / Q000506:poisoning*; D008460:Meat / Q000032:analysis*; D009119:Muscle Contraction / Q000187:drug effects; D012640:Seizures / Q000139:chemically induced / Q000503:physiopathology; D000095702:Polyether Toxins
chemical_list: D000178:Acrylamides; D002922:Ciguatoxins; D003064:Cnidarian Venoms; D008387:Marine Toxins; C010272:palytoxin; D000095702:Polyether Toxins