Precursor lesions of oesophageal cancer in young people in a high-risk population in China.
Young people (15-26 years) were selected from households in a population in China at high risk of oesophageal cancer on the basis of whether a case of oesophageal cancer had (166 participants) or had not (372 participants) occurred in a first-degree relative. In an endoscopic survey 43.5% of the male subjects and 35.9% of the female subjects showed histological signs of chronic oesophagitis. The presence of these precursor lesions was significantly associated in a multivariate logistic model with consumption of burning hot beverages, a family history of oesophageal cancer (including second-degree relatives), infrequent consumption of fresh fruit, and infrequent consumption of dietary staples other than maize.
Wahrendorf
J
J
German Cancer Research Centre, Institute of Epidemiology and Biometry, Heidelberg.
Chang-Claude
J
J
Liang
Q S
QS
Rei
Y G
YG
Muñoz
N
N
Crespi
M
M
Raedsch
R
R
Thurnham
D
D
Correa
P
P
D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D002681:China / Q000453:epidemiology; D002908:Chronic Disease; D004938:Esophageal Neoplasms / Q000453:epidemiology* / Q000209:etiology / Q000235:genetics / Q000473:pathology; D004941:Esophagitis / Q000150:complications / Q000453:epidemiology* / Q000473:pathology; D004945:Esophagoscopy; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D009752:Nutritional Status; D011230:Precancerous Conditions / Q000453:epidemiology* / Q000473:pathology; D015995:Prevalence; D012307:Risk Factors; D012494:Sampling Studies; D011795:Surveys and Questionnaires