title: Prevalence of antibody to human herpesvirus 6 in women and children.
abstract: The antibody prevalence to human herpesvirus 6 (HHV-6) was compared between pregnant women and control women of similar ages in Thailand. No significant difference was detected in the antibody positive rate and antibody titers between both groups. The antibody titers in sera collected from pregnant women at 1st and 3rd trimester remained unchanged. Next, the antibody prevalence in infants were examined and the positive rate decreased until 3 months and started to increase from 6 months after birth. The present results suggest that the reactivation of HHV-6 might not occur during pregnancy and this virus infects infants postnatally.
authors.affiliation: Immunology Section, National Institute of Health, Thailand.
authors.forename: K
authors.initials: K
authors.lastname: Balachandra
authors.forename: P I
authors.initials: PI
authors.lastname: Ayuthaya
authors.forename: W
authors.initials: W
authors.lastname: Auwanit
authors.forename: C
authors.initials: C
authors.lastname: Jayavasu
authors.forename: T
authors.initials: T
authors.lastname: Okuno
authors.forename: K
authors.initials: K
authors.lastname: Yamanishi
authors.forename: M
authors.initials: M
authors.lastname: Takahashi
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006561:Herpes Simplex / Q000453:epidemiology* / Q000276:immunology; D006801:Humans; D007223:Infant; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology; D018139:Simplexvirus / Q000276:immunology; D013785:Thailand; D014775:Virus Activation
chemical_list: D000914:Antibodies, Viral