DNA dot-blot hybridization implicates human papillomavirus type 11-DNA in epithelioma cuniculatum.
Epithelioma cuniculatum is a rare, low-grade squamous cell carcinoma, belonging to the group of verrucous carcinomas. Evidence is presented that suggests that human papilloma virus type-11 may be involved in the pathogenesis of epithelioma cuniculatum. HPV-DNA was detected by dot-blot hybridization with 32P-labelled probe DNA. Plasmids containing HPV-DNA were isolated by the benzoylated naphthoylated DEAE cellulose method (BND-method), an improved procedure for routine detection of HPV-DNA.
Knobler
R M
RM
Department of Dermatology II, University of Vienna, Austria.
Schneider
S
S
Neumann
R A
RA
Bodemer
W
W
Radlwimmer
B
B
Aberer
E
E
Söltz-Szöts
J
J
Gebhart
W
W
D000368:Aged; D015139:Blotting, Southern; D002291:Carcinoma, Papillary / Q000382:microbiology*; D015342:DNA Probes; D015344:DNA Probes, HPV; D004279:DNA, Viral / Q000032:analysis*; D006801:Humans; D008297:Male; D009693:Nucleic Acid Hybridization; D027383:Papillomaviridae / Q000032:analysis* / Q000235:genetics; D012878:Skin Neoplasms / Q000382:microbiology*
D015342:DNA Probes; D015344:DNA Probes, HPV; D004279:DNA, Viral