[Pneumocystis carinii pneumonia in renal transplant recipients treated with cyclosporin].
Four cases of pneumocystis carinii pneumonia occurred among 38 renal transplant recipients. Diagnosis was confirmed by cyst concentration technique in 2 cases. The other 2 cases were clinically, from the rapid improvement of fever, pulmonary infiltrates and hypoxia following a therapeutic trial of high dose sulfamethoxazole-trimethoprim. All patients responded to treatment with high dose sulfamethoxazole-trimethoprim. Three patients survived pneumocystis carinii pneumonia, but i died due to aspergillosis. One patients showed serological evidence of concomitant cytomegalovirus infection.
Kim
C J
CJ
Group of Renal Transplantation, Shiga University of Medical Science.
Pak
K
K
Wakabayashi
Y
Y
Ishida
A
A
Arai
Y
Y
Konishi
T
T
Kounami
T
T
Tomoyoshi
T
T
Sako
H
H
Okino
K
K
D000328:Adult; D003524:Cyclosporins / Q000009:adverse effects*; D003586:Cytomegalovirus Infections / Q000209:etiology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000188:drug therapy / Q000209:etiology*; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy / Q000209:etiology*; D013420:Sulfamethoxazole / Q000627:therapeutic use; D014295:Trimethoprim / Q000627:therapeutic use
D003524:Cyclosporins; D014295:Trimethoprim; D013420:Sulfamethoxazole