title: Removal of anti-HLA antibodies by extracorporeal immunoadsorption to enable renal transplantation.
abstract: 10 highly and persistently sensitised patients awaiting renal transplantation underwent extracorporeal immunoadsorption to remove anti-HLA antibodies. 7 patients have since received transplants. Only 1 allograft has been lost because of rejection, and there have been no serious side-effects attributable to treatment. Extracorporeal immunoadsorption may therefore be of considerable value in the management of highly sensitised patients.
authors.affiliation: Renal Unit, Dulwich Hospital, London.
authors.forename: A
authors.initials: A
authors.lastname: Palmer
authors.forename: D
authors.initials: D
authors.lastname: Taube
authors.forename: K
authors.initials: K
authors.lastname: Welsh
authors.forename: M
authors.initials: M
authors.lastname: Bewick
authors.forename: P
authors.initials: P
authors.lastname: Gjorstrup
authors.forename: M
authors.initials: M
authors.lastname: Thick
mesh_terms: D000328:Adult; D000918:Antibody Specificity; D003520:Cyclophosphamide / Q000008:administration & dosage; D005260:Female; D006084:Graft Rejection; D006680:HLA Antigens / Q000276:immunology*; D006650:Histocompatibility Testing; D006801:Humans; D007163:Immunosorbent Techniques; D007518:Isoantibodies; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D010956:Plasmapheresis; D011241:Prednisone / Q000008:administration & dosage
chemical_list: D006680:HLA Antigens; D007518:Isoantibodies; D003520:Cyclophosphamide; D011241:Prednisone