Testosterone as a factor modifying the toxicity of ekatin for the Pharaoh quail (Coturnix coturnix Pharaoh). I. Mature birds.
1. Testosterone reduces the haemolytic action of Ekatin on the morphotic blood elements by accelerating maturation of erythroblastic cells. 2. Testosterone, by accelerating the metabolism of the pesticide causes a defective defence processes of the organism by decreasing the number of macrophages. 3. Intoxication of androgenised birds with Ekatin leads to a breakdown of the systemic adaptive mechanisms by rapid and early switching on the adrenal cortex in response to the stress caused by poisoning.
Gromysz-Kałkowska
K
K
Department of Animal Physiology, Maria Curie-Skłodowska University, Lublin, Poland.
Szubartowska
E
E
Kaczanowska
E
E
D000818:Animals; D001772:Blood Cell Count; D003370:Coturnix / Q000502:physiology*; D004900:Erythroblasts / Q000187:drug effects; D004906:Erythrocyte Count / Q000187:drug effects; D005260:Female; D006400:Hematocrit; D006454:Hemoglobins / Q000378:metabolism*; D007306:Insecticides / Q000633:toxicity*; D063086:Organothiophosphates / Q000633:toxicity*; D009946:Organothiophosphorus Compounds / Q000633:toxicity*; D011784:Quail / Q000502:physiology*; D012156:Reticulocytes / Q000187:drug effects; D013739:Testosterone / Q000502:physiology*
D006454:Hemoglobins; D007306:Insecticides; D063086:Organothiophosphates; D009946:Organothiophosphorus Compounds; D013739:Testosterone; C100178:thiometon