Changes in urinary electrolytes excretion after injections of ionic solutions into lateral hypothalamic area of rats.
Rats submitted to a chronically implanted cannula into lateral hypothalamic area (LHA) were utilized to study the effect of ionic stimulation of KCl, LiCl and CaCl2, sodium free solutions, on renal water and electrolyte excretion. In a general way decreases in natriuresis and kaliuresis following the injections of solutions into LHA were observed. Furthermore, significant increases in diuresis were noted after the injections of the 0.30 M solutions.
Perez
S E
SE
Universidade Federal de São Paulo.
Silveira
J E
JE
Silva-Netto
C R
CR
D000818:Animals; D002122:Calcium Chloride / Q000494:pharmacology; D002712:Chlorides / Q000494:pharmacology; D004231:Diuresis / Q000187:drug effects*; D007026:Hypothalamic Area, Lateral / Q000187:drug effects* / Q000502:physiology; D007668:Kidney / Q000502:physiology*; D008094:Lithium / Q000494:pharmacology; D018021:Lithium Chloride; D009318:Natriuresis / Q000187:drug effects*; D009994:Osmolar Concentration; D011188:Potassium / Q000652:urine; D011189:Potassium Chloride / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D012964:Sodium / Q000652:urine; D014882:Water-Electrolyte Balance / Q000187:drug effects*
D002712:Chlorides; D011189:Potassium Chloride; D008094:Lithium; D012964:Sodium; D018021:Lithium Chloride; D002122:Calcium Chloride; D011188:Potassium