[Inhibitory effect of electroacupuncture on cAMP induced ECOG epileptiform waves].
In conscious rabbits, injection of cAMP (100 micrograms in 100 microliters, icv) elicited high-amplitude and high-frequency epileptiform seizure pattern of ECoG. The epileptic waves were inhibited by electro-acupuncturing bilateral "Zusanli" Points. During and after the cessation of electro-acupuncture the frequency, amplitude and duration of epileptiform discharges decreased significantly, the seizure waves even disappeared completely. The frequency and amplitude of epileptic waves showed significant difference in comparison with those of the non-electroacupuncture group (p less than 0.001 and p less than 0.01 respectively), the duration of epileptic waves shortened by 58.18-66.88%. The results suggested that electroacupuncture has antiepileptic action on c-AMP induced experimental epileptic seizure.
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D015670:Acupuncture Therapy; D000818:Animals; D002540:Cerebral Cortex / Q000502:physiology; D000242:Cyclic AMP; D015671:Electroacupuncture; D004594:Electrophysiology; D004827:Epilepsy / Q000139:chemically induced / Q000628:therapy*; D005260:Female; D007276:Injections, Intraventricular; D008297:Male; D011817:Rabbits
D000242:Cyclic AMP