Congenital malformations and oral poliovirus vaccination during pregnancy.
In February, 1985, mass vaccination with live oral poliovirus vaccine (OPV) was started during a poliomyelitis outbreak in Finland. Pregnant women were advised to take the vaccination. Judged as the rate of reported malformations, OPV during early pregnancy had no harmful effects on fetal development.
Harjulehto
T
T
Department of Pathology, University of Helsinki, Finland.
Aro
T
T
Hovi
T
T
Saxén
L
L
D000014:Abnormalities, Drug-Induced / Q000453:epidemiology / Q000209:etiology*; D000015:Abnormalities, Multiple / Q000139:chemically induced*; D000328:Adult; D004196:Disease Outbreaks; D004341:Drug Evaluation; D005260:Female; D005387:Finland; D006801:Humans; D007231:Infant, Newborn; D011051:Poliomyelitis / Q000517:prevention & control*; D011055:Poliovirus Vaccine, Oral / Q000009:adverse effects*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000517:prevention & control*; D014611:Vaccination / Q000009:adverse effects*
D011055:Poliovirus Vaccine, Oral