[Status of the hypophyseo-adrenal system and functional morphology of the adrenal glands in residents of Northern European areas of the USSR].
Serum corticotropin and cortisol levels were measured in 20-40-year old healthy residents (144 males and 361 females) in the North. A functional Synacthen Depot test was performed in 5 volunteers. The adrenal glands from 56 males and 8 females of the same age who had died from accidents were pathohistologically and stereometrically examined. The signs of functional tension were established in the pituitary-adrenal cortex system. The Synacthen Depot test determined sufficient potentials of the organ to show responses to specific stimulation. Morphologically, a number of changes were found, which might be regarded as a prerequisite to the development of functional and pathological disturbances in the above-mentioned link of the endocrine system.
Sukhanov
S G
SG
Tkachev
A V
AV
D000222:Adaptation, Physiological; D000302:Adrenal Cortex / Q000033:anatomy & histology / Q000187:drug effects / Q000502:physiology*; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D001110:Arctic Regions; D003366:Cosyntropin / Q000494:pharmacology; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D010913:Pituitary-Adrenal System / Q000187:drug effects / Q000502:physiology*; D014586:USSR
D003366:Cosyntropin; C006418:adrenocorticotropin zinc; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone
Sostoianie gipofizarno-adrenalovoĭ sistemy i funktsional'naia morfologiia nadpochchechnikov u zhiteleĭ evropeĭskogo severa.