A study on the antiviral action of a polyphenolic complex isolated from the medicinal plant Geranium sanguineum L. VIII. Inhibitory effect on the reproduction of herpes simplex virus type 1.
The antiviral activity of a polyphenolic complex, isolated from a Bulgarian medicinal plant Geranium sanguineum L., on the reproduction of herpes simplex virus type 1 was studied. The substance inhibited the intracellular stages of viral replication and exhibited a virucidal effect.
Zgorniak-Nowosielska
I
I
Zawilinska
B
B
Manolova
N
N
Serkedjieva
J
J
D000998:Antiviral Agents / Q000494:pharmacology*; D002031:Bulgaria; D003864:Depression, Chemical; D004305:Dose-Response Relationship, Drug; D005419:Flavonoids; D010636:Phenols / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D011108:Polymers / Q000494:pharmacology*; D059808:Polyphenols; D018139:Simplexvirus / Q000187:drug effects* / Q000502:physiology; D013997:Time Factors; D014776:Virus Cultivation; D014779:Virus Replication / Q000187:drug effects* / Q000502:physiology
D000998:Antiviral Agents; D005419:Flavonoids; D010636:Phenols; D010936:Plant Extracts; D011108:Polymers; D059808:Polyphenols