title: The effect of machine speed on the consolidation of four directly compressible tablet diluents.
abstract: The reduction in porosity of a powder bed on compression was found to be a function of the velocity of the punch of the press. Substances which consolidated principally by fragmentation showed relatively little velocity dependence. However, the more important deformation was in a powder's consolidation mechanism, the greater the dependence on punch velocity and hence tablet press speed.
authors.affiliation: Welsh School of Pharmacy, University of Wales College of Cardiff, UK.
authors.forename: N A
authors.initials: NA
authors.lastname: Armstrong
authors.forename: L P
authors.initials: LP
authors.lastname: Palfrey
mesh_terms: D002626:Chemistry, Pharmaceutical; D005079:Excipients; D006244:Hardness; D011312:Pressure; D013607:Tablets; D013678:Technology, Pharmaceutical; D013718:Tensile Strength
chemical_list: D005079:Excipients; D013607:Tablets