[A comparative analysis of the effect of an analog of vasopressin on functionally different neurons in the grape snail].
Application of desglycine-argininvasopressin (DG-AVP) differently influenced different types of cells of snail isolated central nervous system. In neurosecretory cells an increase of spontaneous impulse activity took place and, as a rule, bursts of impulses appeared, most often of synaptic origin, excluding PPa1 neurones and one of the neurosecretory cells of the left parietal ganglion. The increase of the bursts activity in these cells was based on the increase of the amplitude of membrane potential waves. Under the influence of neurosecretory cells system activation, EPSPs frequency and amplitude in secondary-sensory neurones increased, which led to a greater probability of the action potentials appearance. At prolonged action the spontaneous EPSPs in these cells began to group in bursts. Excitability and membrane resistance of these cells remained unchanged. DG-AVP had no influence on primary-sensory neurones and motoneurones.
Kudriashova
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D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D001127:Arginine Vasopressin / Q000031:analogs & derivatives* / Q000494:pharmacology; D006372:Helix, Snails / Q000166:cytology* / Q000187:drug effects; D066298:In Vitro Techniques; D009046:Motor Neurons / Q000187:drug effects / Q000502:physiology; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D009490:Neurosecretory Systems / Q000166:cytology / Q000187:drug effects; D009435:Synaptic Transmission / Q000187:drug effects
D001127:Arginine Vasopressin; C015119:argipressin, des-GlyNH2(9)-
Sravnitel'naia analiz deĭstviia analoga vazopressina na funktsional'no raznye neĭrony u vinogradnoĭ ulitki.