Tardive oculogyric crises.
Involuntary ocular deviations, or oculogyric crises (OGC), commonly occur in acute dystonic reactions to dopamine receptor blocking drugs (neuroleptics). We describe 4 patients with tardive OGC due to prolonged exposure to neuroleptics. In addition to the OGC, the patients had other tardive movement disorders. All patients improved with tetrabenazine. We conclude that tardive OGC are often not recognized and represent part of the spectrum of tardive dystonia.
FitzGerald
P M
PM
Department of Neurology, Baylor College of Medicine, Houston, TX 77030
Jankovic
J
J
D000368:Aged; D014150:Antipsychotic Agents / Q000009:adverse effects; D004409:Dyskinesia, Drug-Induced / Q000188:drug therapy / Q000503:physiopathology; D005133:Eye Movements / Q000187:drug effects; D005260:Female; D006801:Humans; D008875:Middle Aged; D010640:Phenothiazines / Q000009:adverse effects*; D013747:Tetrabenazine / Q000627:therapeutic use
D014150:Antipsychotic Agents; D010640:Phenothiazines; D013747:Tetrabenazine