title: Hyperpigmented acral papular mucinosis, systemic lupus erythematosus and universal alopecia.
abstract: A 42-year-old man presented with systemic lupus erythematosus, universal alopecia and non-pruritic hyperpigmented papular mucinosis. The latter was most evident on acral areas. In hyperpigmented areas of the face the immunofluorescence showed deposits as in LE and with alcian blue and colloidal iron an abundance of mucin was demonstrated in the dermis. A lesion on the back showed only papular mucinosis. Fifteen cases of LE and papular mucinosis reported in the literature are reviewed. Our patient differs with respect to the marked pigmentation of his lesions, their localization and the association with universal alopecia.
authors.affiliation: Department of Dermatology, University of Nice, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Lacour
authors.forename: L
authors.initials: L
authors.lastname: Juhlin
authors.forename: P
authors.initials: P
authors.lastname: el Baze
authors.forename: H
authors.initials: H
authors.lastname: Duplay
authors.forename: J P
authors.initials: JP
authors.lastname: Ortonne
mesh_terms: D000328:Adult; D000505:Alopecia / Q000150:complications*; D001706:Biopsy; D005455:Fluorescent Antibody Technique; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000378:metabolism; D008297:Male; D009077:Mucins / Q000096:biosynthesis*; D010859:Pigmentation Disorders / Q000150:complications* / Q000378:metabolism / Q000473:pathology
chemical_list: D009077:Mucins