title: Detection of missing vesicoureteral reflux with bethanechol chloride-aided voiding cystourethrography.
abstract: Experience in the detection of absent vesicoureteral reflux with bethanechol-aided voiding cystourethrography is presented. The detection rate with conventional contrast-enhanced voiding cystourethrography among 9 study subjects, in whom vesicoureteral reflux otherwise was highly suspected from accompanying clinical, urographic and endoscopic features, and in whom it was absent contralaterally or bilaterally, was improved from 33 per cent (only 3 of 9 patients were positive for reflux) to 100 per cent (all 9 were proved to have vesicoureteral reflux) after bethanechol stimulation. Some representative cases are presented and the mechanisms of inducing vesicoureteral reflux with bethanechol are discussed as well as its clinical relevance. Bethanechol-aided voiding cystourethrography is suggested as a highly sensitive method to detect absent vesicoureteral reflux.
authors.affiliation: Department of Urology, Hokkaido University School of Medicine, Sapporo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Koyanagi
authors.forename: H
authors.initials: H
authors.lastname: Morita
authors.forename: T
authors.initials: T
authors.lastname: Gotoh
authors.forename: K
authors.initials: K
authors.lastname: Nonomura
authors.forename: M
authors.initials: M
authors.lastname: Togashi
authors.forename: M
authors.initials: M
authors.lastname: Nantani
mesh_terms: D000328:Adult; D018723:Bethanechol; D001626:Bethanechol Compounds; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D011859:Radiography; D014521:Urethra / Q000000981:diagnostic imaging*; D001743:Urinary Bladder / Q000000981:diagnostic imaging*; D014554:Urination; D014718:Vesico-Ureteral Reflux / Q000000981:diagnostic imaging*
chemical_list: D001626:Bethanechol Compounds; D018723:Bethanechol