title: Insight in schizophrenia. Its relationship to acute psychopathology.
abstract: The relationship between insight and acute psychopathology was explored in a group of 52 acutely psychotic, schizophrenic patients. A measure of insight, reflecting patients' recognition of their illness and need for care, was validated against ratings from a semi-structured interview and against assessments of patients' compliance with medication. Contrary to expectations, degree of insight was not consistently related to the severity of acute psychopathology, as measured on two structured scales. Nor did changes in insight during hospitalization vary consistently with changes in acute psychopathology. These data suggest that very little of the deficiency in insight seen in schizophrenic patients is explainable on the basis of acute psychopathological features. The mechanism that accounts for impairment in insight in schizophrenia may be relatively resistant to treatment with neuroleptic medication.
authors.affiliation: Department of Psychiatry, University of Pittsburgh, PA.
authors.forename: J P
authors.initials: JP
authors.lastname: McEvoy
authors.forename: L J
authors.initials: LJ
authors.lastname: Apperson
authors.forename: P S
authors.initials: PS
authors.lastname: Appelbaum
authors.forename: P
authors.initials: P
authors.lastname: Ortlip
authors.forename: J
authors.initials: J
authors.lastname: Brecosky
authors.forename: K
authors.initials: K
authors.lastname: Hammill
authors.forename: J L
authors.initials: JL
authors.lastname: Geller
authors.forename: L
authors.initials: L
authors.lastname: Roth
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001294:Attitude to Health; D001364:Awareness; D003071:Cognition; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000175:diagnosis* / Q000188:drug therapy; D012565:Schizophrenic Psychology
chemical_list: D014150:Antipsychotic Agents