title: Susceptibility of non-fermentative gram-negative organisms to ureidopenicillins and quinolones.
abstract: The susceptibility of non-fermentative Gram-negative bacteria (excluding Pseudomonas aeruginosa) to ureidopenicillins and new quinolones was investigated. The ureidopenicillins were not active against the strains except against Pseudomonas species, 90% of which were inhibited by 64 mg/l. The new quinolones, particularly ciprofloxacin, had excellent activity (MIC range 0.06-8 mg/l) against these strains which included those resistant to beta-lactams and aminoglycosides. This suggested a promising alternative group of compounds to be used in chemotherapy of infections caused by non-fermenters.
authors.forename: F
authors.initials: F
authors.lastname: Moosdeen
authors.forename: S S
authors.initials: SS
authors.lastname: Tee
authors.forename: C K
authors.initials: CK
authors.lastname: Eng
authors.forename: H
authors.initials: H
authors.lastname: Yunus
mesh_terms: D004352:Drug Resistance, Microbial; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests; D010406:Penicillins / Q000494:pharmacology*; D015363:Quinolones / Q000494:pharmacology*
chemical_list: D010406:Penicillins; D015363:Quinolones