The combination of interleukin 1 plus tumor necrosis factor causes greater generation of LTB4, thromboxanes and aggregation on human macrophages than these compounds alone.
Conti
P
P
Department of Immunology, University of Chieti, Italy.
Reale
M
M
Barbacane
R C
RC
Bongrazio
M
M
Panara
M R
MR
Fiore
S
S
D002449:Cell Aggregation / Q000187:drug effects; D004357:Drug Synergism; D006801:Humans; D066298:In Vitro Techniques; D007375:Interleukin-1 / Q000008:administration & dosage / Q000494:pharmacology*; D007975:Leukotriene B4 / Q000378:metabolism*; D008264:Macrophages / Q000187:drug effects / Q000378:metabolism; D013928:Thromboxane A2 / Q000378:metabolism*; D014409:Tumor Necrosis Factor-alpha / Q000008:administration & dosage / Q000494:pharmacology*
D007375:Interleukin-1; D014409:Tumor Necrosis Factor-alpha; D007975:Leukotriene B4; D013928:Thromboxane A2