Separation of the sodium and potassium currents from an action potential of a single active fiber.
A method for calculation of the sodium and potassium currents of an active fiber is presented. The method includes the determination of the transmembrane ionic current, the sodium Nernst potential and the sodium conductivity as well. The method was illustrated by using an action potential of a single striated frog muscle fiber. The derivatives of the experimentally recorded action potential, necessary for calculation of the ionic current, were obtained by means of Fourier transform.
Trayanova
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Central Laboratory of Biophysics, Bulgarian Academy of Sciences, Sofia.
D000200:Action Potentials / Q000187:drug effects; D008433:Mathematics; D008954:Models, Biological; D009474:Neurons / Q000187:drug effects*; D015221:Potassium Channels / Q000187:drug effects*; D015222:Sodium Channels / Q000187:drug effects*
D015221:Potassium Channels; D015222:Sodium Channels