title: How steroid hormones work.
abstract: Understanding how steroids work has led to improved comprehension of such derangements of hormonal regulation as testicular feminization. This knowledge has found practical application in the treatment of hormone-dependent cancers. Gene therapy, albeit still too primitive to correct steroid-response defects, promises to be a future mainstay of management.
authors.affiliation: Division of Endocrinology and Metabolism, University of Arkansas College of Medicine, Little Rock.
authors.forename: R W
authors.initials: RW
authors.lastname: Harrison
authors.forename: S S
authors.initials: SS
authors.lastname: Lippman
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D005786:Gene Expression Regulation / Q000187:drug effects; D006801:Humans; D008324:Mammary Tumor Virus, Mouse / Q000187:drug effects / Q000235:genetics; D051379:Mice; D008969:Molecular Sequence Data; D011519:Proto-Oncogenes / Q000187:drug effects; D011987:Receptors, Steroid / Q000032:analysis / Q000302:isolation & purification / Q000502:physiology*; D013256:Steroids / Q000494:pharmacology / Q000502:physiology*; D013329:Structure-Activity Relationship
chemical_list: D011987:Receptors, Steroid; D013256:Steroids