RFLPs tightly linked with cystic fibrosis: value of probes at the D7S23 locus in prenatal diagnosis.
In a 1:4 risk family, the usefulness of probes at the D7S23 locus for prenatal diagnosis of cystic fibrosis is discussed by comparison with probes at the MET, D7S8, and D7S18 loci that did not allow accuracy in this family.
Vasseur
F
F
Service de Génétique, Faculté de Médecine, Lille, France.
Flactif
M
M
Savary
J B
JB
Turpin
D
D
Deminatti
M M
MM
D003550:Cystic Fibrosis / Q000175:diagnosis / Q000235:genetics*; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000235:genetics*; D008040:Genetic Linkage; D005819:Genetic Markers; D006239:Haplotypes; D006801:Humans; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods*
D005819:Genetic Markers