title: Paget's disease of the male breast--report of a case and histopathologic study.
abstract: We report a 61-year-old male with mammary Paget's disease. Physical examination revealed a slightly exudative erythema at the areola and a reddish, enlarged left nipple. No tumor or left axillary lymph nodes was palpable. He underwent a left modified radical mastectomy. Histologically, there was an intraductal carcinoma in the upper portion of the mammary ducts. The axillary lymph nodes that were examined were free of metastasis. Paget cells had neither estrogen nor progesterone receptors. We speculated that the histogenesis of Paget cells involved carcinoma cells that invaded the epidermis of the nipple.
authors.forename: Y
authors.initials: Y
authors.lastname: Sano
authors.forename: T
authors.initials: T
authors.lastname: Inoue
authors.forename: M
authors.initials: M
authors.lastname: Aso
authors.forename: Y
authors.initials: Y
authors.lastname: Hagari
authors.forename: K
authors.initials: K
authors.lastname: Hattori
authors.forename: S
authors.initials: S
authors.lastname: Shimao
authors.forename: T
authors.initials: T
authors.lastname: Notsu
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology*; D006801:Humans; D008297:Male; D015411:Mastectomy, Modified Radical; D008875:Middle Aged; D010144:Paget's Disease, Mammary / Q000473:pathology* / Q000601:surgery; D011960:Receptors, Estrogen / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis
chemical_list: D011960:Receptors, Estrogen; D011980:Receptors, Progesterone