title: Localization of polymorphic DNA probes frequently deleted in lung carcinoma.
abstract: Five polymorphic DNA segments from human chromosome 3, that are frequently deleted in lung carcinoma were mapped by non-isotopic in situ hybridization to metaphase chromosomes. The DNA segment D3S3 mapped to 3p13-p14.2, D3S6 to 3p14.3-p14.5, D3S48 to distal 3p21-p22, ERBA beta to 3p24.3 and ERBA2 to 3p24.3. The map location of ERBA beta and ERBA2 was confirmed by re-mapping each probe in combination with D3S6 as a marker for 3p14.
authors.affiliation: MRC Molecular Genetics Unit, MRC Center, Cambridge, UK.
authors.forename: D G
authors.initials: DG
authors.lastname: Albertson
authors.forename: P D
authors.initials: PD
authors.lastname: Sherrington
authors.forename: P H
authors.initials: PH
authors.lastname: Rabbitts
mesh_terms: D018288:Carcinoma, Small Cell / Q000235:genetics*; D002871:Chromosome Banding; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D002893:Chromosomes, Human, Pair 3; D015342:DNA Probes; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D008175:Lung Neoplasms / Q000235:genetics*; D009693:Nucleic Acid Hybridization; D011110:Polymorphism, Genetic
chemical_list: D015342:DNA Probes; D005819:Genetic Markers