title: Sulfasalazine: a potential psoriasis therapy?
abstract: In an open study, 32 patients with moderate to severe stable plaque psoriasis were treated with sulfasalazine, 3 gm daily for 8 weeks. Twenty-four patients completed the study, and 19 had modest to marked improvement or clearing. If confirmed by a double-blind study, sulfasalazine could become an alternative therapy in some patients with moderate to severe psoriasis.
authors.affiliation: University of Michigan Medical Center, Department of Dermatology, Ann Arbor 48109-0314.
authors.forename: A K
authors.initials: AK
authors.lastname: Gupta
authors.forename: C N
authors.initials: CN
authors.lastname: Ellis
authors.forename: M T
authors.initials: MT
authors.lastname: Siegel
authors.forename: J J
authors.initials: JJ
authors.lastname: Voorhees
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000188:drug therapy*; D012460:Sulfasalazine / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D012460:Sulfasalazine