Variable expression of P fimbriae in Escherichia coli urinary tract infection.
Fresh urinary isolates were examined by immunofluorescence with polyclonal rabbit antibodies against type 1 and P fimbriae. This procedure showed P-fimbriate Escherichia coli in 22 of 24 samples from patients with asymptomatic bacteriuria, 24 of 26 samples from patients with cystitis, and 6 of 6 samples from patients with pyelonephritis. Type 1 fimbriae were expressed by less than 40% of isolates in all three groups. There was no relation between the presence of symptoms or the site of infection and fimbrial expression, of P or type 1, by bacteria adherent to freshly isolated uroepithelial cells.
Lichodziejewska
M
M
KRUF Institute of Renal Disease, University of Wales College of Medicine, Royal Infirmary, Cardiff.
Topley
N
N
Steadman
R
R
Mackenzie
R K
RK
Jones
K V
KV
Williams
J D
JD
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000907:Antibodies, Bacterial; D001422:Bacterial Adhesion; D001789:Blood Group Antigens / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D004926:Escherichia coli / Q000276:immunology / Q000302:isolation & purification / Q000378:metabolism; D004927:Escherichia coli Infections / Q000652:urine*; D010861:Fimbriae, Bacterial / Q000032:analysis* / Q000145:classification / Q000378:metabolism / Q000648:ultrastructure; D006801:Humans; D008722:Methods; D008854:Microscopy, Electron; D008875:Middle Aged; D010127:P Blood-Group System / Q000276:immunology*; D014552:Urinary Tract Infections / Q000652:urine*
D000907:Antibodies, Bacterial; D001789:Blood Group Antigens; D010127:P Blood-Group System