Aging related changes of neurotransmitters in the visual system.
Different neurotransmitter systems in the retina and optic nerve can be modified during aging. An increase in GABA and dopamine receptor density in the retina of senescent rats has been demonstrated. Lack of data exists on the aging-related changes in optic nerve neurotransmitters. However, it is possible that neurotransmitter changes in the optic nerve at the lateral geniculate nucleus are similar to those in other areas of central nervous system.
Drago
F
F
Institute of Pharmacology, University of Catania, Medical School, Italy.
Gagliano
C
C
Cavaliere
S
S
D000375:Aging / Q000502:physiology*; D000818:Animals; D005123:Eye / Q000378:metabolism*; D051379:Mice; D018377:Neurotransmitter Agents / Q000378:metabolism*; D009900:Optic Nerve / Q000378:metabolism*; D011817:Rabbits; D051381:Rats; D011954:Receptors, Dopamine / Q000378:metabolism; D011963:Receptors, GABA-A / Q000378:metabolism; D012160:Retina / Q000378:metabolism; D014795:Visual Pathways / Q000378:metabolism
D018377:Neurotransmitter Agents; D011954:Receptors, Dopamine; D011963:Receptors, GABA-A