title: Narcotic analgesics and debrisoquine polymorphism.
authors.forename: K L
authors.initials: KL
authors.lastname: Lavrijsen
authors.forename: J J
authors.initials: JJ
authors.lastname: Heykants
mesh_terms: D000701:Analgesics, Opioid / Q000493:pharmacokinetics*; D019389:Cytochrome P-450 CYP2D6; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D003647:Debrisoquin / Q000493:pharmacokinetics*; D006801:Humans; D066298:In Vitro Techniques; D007546:Isoquinolines / Q000493:pharmacokinetics*; D008862:Microsomes, Liver / Q000201:enzymology; D006899:Mixed Function Oxygenases / Q000378:metabolism; D011110:Polymorphism, Genetic / Q000187:drug effects*
chemical_list: D000701:Analgesics, Opioid; D007546:Isoquinolines; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D019389:Cytochrome P-450 CYP2D6; D003647:Debrisoquin