[Comparative carcinogenic properties of basalt fiber and chrysotile-asbestos].
In order to eliminate asbestos adverse effect on workers' health it was necessary to use mineral rayon, primarily basalt fibre, instead of asbestos. During a chronic experiment on animals the oncogenicity of 2 kinds of basalt fibre was studied compared to chrysotile asbestos. The dust dose of 25 mg was twice administered by intraperitonial route. All types of dust induced the onset of intraperitonial mesotheliomas but neoplasm rates were significantly lower in the groups exposed to basalt fibre. There was no credible data on the differences between the groups exposed to various types of basalt fibre. Since the latter produced some oncogenic effect, it was necessary to develop a complex of antidust measures, fully corresponding to the measures adopted for carcinogenic dusts.
Nikitina
O V
OV
Kogan
F M
FM
Vanchugova
N N
NN
Frash
V N
VN
D000818:Animals; D001194:Asbestos / Q000009:adverse effects*; D017632:Asbestos, Serpentine; D008654:Mesothelioma / Q000209:etiology*; D008903:Minerals / Q000009:adverse effects*; D010534:Peritoneal Neoplasms / Q000209:etiology*; D051381:Rats; D012307:Risk Factors; D017640:Silicates; D012822:Silicon Dioxide / Q000009:adverse effects*
D017632:Asbestos, Serpentine; D008903:Minerals; D017640:Silicates; C060346:basalt; D001194:Asbestos; D012822:Silicon Dioxide
Sravnitel'naia onkogennost' bazal' tovykh volokon i khrizotil-asbesta.