title: Variations in red blood cell polyamines in brain tumour patients treated with stereotactic radiosurgery.
abstract: Red blood cell polyamine levels were followed in 13 patients treated with stereotactic radiosurgery for various types of brain tumours. In the most malignant tumours radiosurgery resulted in a decrease in spermine and an increase in spermidine levels. This discrepancy between variations in polyamine levels was not found after conventional radiotherapy. The results may indicate a change in tumour polyamine activity induced by high energy radiotherapy.
authors.affiliation: Department of Neurosurgery, University of Birmingham, Warley, West Midlands, UK.
authors.forename: C
authors.initials: C
authors.lastname: von Essen
authors.forename: P
authors.initials: P
authors.lastname: Elworthy
authors.forename: E
authors.initials: E
authors.lastname: Hitchcock
mesh_terms: D000236:Adenoma / Q000097:blood* / Q000532:radiotherapy / Q000601:surgery; D000293:Adolescent; D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000097:blood* / Q000532:radiotherapy / Q000601:surgery; D002648:Child; D003397:Craniopharyngioma / Q000097:blood* / Q000532:radiotherapy / Q000601:surgery; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D005910:Glioma / Q000097:blood* / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D009026:Mortality; D010911:Pituitary Neoplasms / Q000097:blood* / Q000532:radiotherapy / Q000601:surgery; D011073:Polyamines / Q000097:blood*; D013238:Stereotaxic Techniques; D013997:Time Factors
chemical_list: D011073:Polyamines