Norfenefrine in the treatment of female urinary stress incontinence assessed by one-hour pad weighing test.
Thirty-three women with urinary stress incontinence were treated with the alpha-adrenoceptor-stimulating agent, norfenefrine (Nevadral Retard). Treatment was administered during 3-24 weeks at a daily dosage of 90 mg. Judged by a 1-hour pad weighing test, a significant effect could be demonstrated. With the exception of 1 case of allergic reaction and 1 case of recurrent vomiting, a simultaneously performed tolerability test revealed only minor side effects.
Diernaes
E
E
Department of Gynaecology and Obstetrics, Kolding Hospital, Denmark.
Rix
P
P
Sørensen
T
T
Alexander
N
N
D015078:2-Hydroxyphenethylamine / Q000031:analogs & derivatives / Q000627:therapeutic use* / Q000633:toxicity; D000316:Adrenergic alpha-Agonists / Q000627:therapeutic use* / Q000633:toxicity; D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008875:Middle Aged; D009655:Octopamine / Q000031:analogs & derivatives*; D010627:Phenethylamines / Q000627:therapeutic use*; D013997:Time Factors; D014550:Urinary Incontinence, Stress / Q000175:diagnosis / Q000188:drug therapy*; D014556:Urine
D000316:Adrenergic alpha-Agonists; D010627:Phenethylamines; D009655:Octopamine; D015078:2-Hydroxyphenethylamine; C005310:norfenefrine