[Experimental research on the pathogenic mechanisms in adult respiratory distress syndrome].
In order to study the pathogenic mechanisms of adult respiratory distress syndrome (ARDS), the neutrophil aggregation activity, platelet aggregation rate and levels of thromboxane, prostacyclin, superoxide dismutase, lipoperoxides, neutrophil elastase, alpha 1-antitrypsin and angiotensin conversion enzyme were measured in 84 experimental dogs. Under the action of activated complement C5a, polymorphonuclear leukocyte aggregation with increased release of oxygen radicals play an important role in the pathogenesis of ARDS.
Mao
B L
BL
Guo
X J
XJ
D000818:Animals; D015936:Complement C5a / Q000276:immunology; D004285:Dogs; D007703:Peptidyl-Dipeptidase A / Q000378:metabolism; D010974:Platelet Aggregation; D012128:Respiratory Distress Syndrome / Q000097:blood / Q000201:enzymology / Q000209:etiology*; D013482:Superoxide Dismutase / Q000378:metabolism
D015936:Complement C5a; D013482:Superoxide Dismutase; D007703:Peptidyl-Dipeptidase A