[Immunomodulating properties of interferon inducers].
Data on the immunomodulating activity of interferon inductors are presented. It was revealed that the inductors increased the animal vaccinal response. Schemes for combined use of the interferon inductors and immunomodulators were developed. The immunomodulators were shown to increase the host interferon response evident from synergistic increasing of the interferon titers or prolongation of interferon circulation in blood of the animals. The efficiency of the schemes for combined use of the interferon inductors and immunomodulators was obvious from stimulation of the antibody production. As a result the time of the antibody circulation in blood increased. The effect of the combined use of the immunomodulators and interferon inductors was studied. The combined use of the preparations significantly increased the average life-span of the animals and the rate of their survival.
Ershov
F I
FI
Tazulakhova
E B
EB
D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis*; D002506:Cephalexin / Q000276:immunology / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D009980:Influenza A virus / Q000276:immunology*; D007252:Influenza Vaccines / Q000494:pharmacology*; D007369:Interferon Inducers / Q000276:immunology / Q000494:pharmacology*; D007370:Interferon Type I / Q000096:biosynthesis* / Q000276:immunology; D008214:Lymphocytes / Q000378:metabolism; D051379:Mice; D008808:Mice, Inbred CBA; D011068:Poly G / Q000276:immunology / Q000494:pharmacology; D018139:Simplexvirus / Q000276:immunology*; D013154:Spleen / Q000166:cytology; D014765:Viral Vaccines / Q000276:immunology / Q000494:pharmacology*
D000914:Antibodies, Viral; D007252:Influenza Vaccines; D007369:Interferon Inducers; D007370:Interferon Type I; D014765:Viral Vaccines; D011068:Poly G; D002506:Cephalexin
Immunomoduliruiushchie svoĭstva induktorov interferona.