title: HPV 16-positive bowenoid papulosis and squamous-cell carcinoma of the anus in an HIV-positive man.
abstract: A homosexual man in stage IV of HIV infection, who suffers from HPV 16-positive bowenoid papulosis of the anal region, is described. In one area the patient developed an HPV 16-positive squamous-cell carcinoma of the anus. Bowenoid papulosis represents a squamous-cell carcinoma in situ, and usually follows a benign clinical course. The possibility exists that immunocompromised individuals are at higher risk to develop cancer on the basis of bowenoid papulosis.
authors.affiliation: Department of Dermatology, Zürich University Hospital, Switzerland.
authors.forename: R
authors.initials: R
authors.lastname: Rüdlinger
authors.forename: P
authors.initials: P
authors.lastname: Buchmann
mesh_terms: D000328:Adult; D001005:Anus Neoplasms / Q000382:microbiology*; D001913:Bowen's Disease / Q000382:microbiology*; D002294:Carcinoma, Squamous Cell / Q000382:microbiology*; D004279:DNA, Viral / Q000032:analysis*; D006679:HIV Seropositivity / Q000382:microbiology*; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000382:microbiology*; D027383:Papillomaviridae / Q000302:isolation & purification*
chemical_list: D004279:DNA, Viral