title: [An unusual cause of gangrene: cold injury caused by liquid nitrogen].
abstract: A case is described of gangrene of the foot and lower leg due to cold injury following exposure to liquid nitrogen. The severe damage to the entire microcirculation was followed by irreversible ischemia finally requiring amputation of the lower leg. Histology revealed conspicuous lesions of the small vessels within the entire soft tissues, with subsequent thrombotic occlusion and circulatory blockade. Some recommendations concerning occupational exposure to liquid nitrogen are added.
authors.affiliation: Institut für Pathologie, Universität Zürich.
authors.forename: H J
authors.initials: HJ
authors.lastname: Leu
authors.forename: L
authors.initials: L
authors.lastname: Clodius
mesh_terms: D000062:Accidents, Occupational; D000671:Amputation, Surgical; D005528:Foot / Q000473:pathology / Q000601:surgery; D018409:Foot Injuries; D005627:Frostbite / Q000209:etiology* / Q000473:pathology; D005734:Gangrene; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D009584:Nitrogen / Q000009:adverse effects*
chemical_list: D009584:Nitrogen
vernacular_title: Eine seltene Ursache der Gangrän: die Erfrierung durch flüssigen Stickstoff.