Possible interaction of potassium embelate, a putative analgesic agent, with opiate receptors.
The in vivo studies have been carried out in the rat brain for characterization of binding sites for potassium embelate (ex: Embelia ribes) a potent centrally acting analgesic compound. The results indicate that mixed mu and kappa binding sites in the brain may be involved in the analgesic action of this compound.
Zutshi
U
U
Johri
R K
RK
Atal
C K
CK
D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D016227:Benzoquinones; D001921:Brain / Q000187:drug effects; D005260:Female; D008297:Male; D011809:Quinones / Q000494:pharmacology*; D051381:Rats; D011957:Receptors, Opioid / Q000187:drug effects*
D000700:Analgesics; D016227:Benzoquinones; D011809:Quinones; D011957:Receptors, Opioid; C010945:embelin