Growth hormone and somatostatin in the plasma of transiently diabetic ducks: basal variation and response to glucose.
In the duck, subtotal pancreatectomy induces a transient diabetes, with decreased insulin and glucagon basal levels as well as responses to glucose. At the same time, a transient increase in basal peripheral somatostatin occurs, followed by an increase in growth hormone in the postdiabetic state. Intravenous glucose induces a slight decrease in somatostatin secretion in normal, but not in diabetic animals, and no significant variation in growth hormone secretion at any state. An obvious role of growth hormone or somatostatin in the development of this transient diabetes in the duck could not be detected in this study.
Laurent
F
F
Institut de Physiologie, Strasbourg, France.
Karmann
H
H
Harvey
S
S
Foltzer
C
C
Mialhe
P
P
D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism*; D004372:Ducks; D005934:Glucagon / Q000097:blood; D005947:Glucose / Q000494:pharmacology*; D013006:Growth Hormone / Q000097:blood*; D007328:Insulin / Q000097:blood; D008297:Male; D010180:Pancreatectomy; D013004:Somatostatin / Q000097:blood*; D013997:Time Factors
D007328:Insulin; D013004:Somatostatin; D013006:Growth Hormone; D005934:Glucagon; D005947:Glucose