Coexistence of enkephalin and somatostatin in the chicken retina.
A double immunostaining method was used in the present study to demonstrate that enkephalin (ENK) and somatostatin (SOM) coexist within single amacrine cells of the chicken retina. The ratio of double-labeled cells to either ENK- or SOM-bearing cells was more than 90%, indicating that retinal ENK and SOM are most likely to be found together in the same amacrine cell. This rate of colocalization is the highest yet observed among any neurotransmitters and modulators that coexist.
Hamano
K
K
Department of Ophthalmology, Osaka University Medical School, Japan.
Katayama-Kumoi
Y
Y
Kiyama
H
H
Ishimoto
I
I
Manabe
R
R
Tohyama
M
M
D000818:Animals; D002645:Chickens; D004745:Enkephalins / Q000378:metabolism*; D007150:Immunohistochemistry; D012160:Retina / Q000166:cytology / Q000378:metabolism*; D013004:Somatostatin / Q000378:metabolism*
D004745:Enkephalins; D013004:Somatostatin