title: Action of a bacterial Achromobacter collagenase on the soft carious dentine: an in vitro study with the scanning electron microscope.
abstract: Samples of carious human teeth treated in vitro for 48-92 hours with a bacterial Achromobacter collagenase in solution in borate buffer at 33 degrees were examined with the scanning electron microscope. The enzyme was seen to destroy soft carious dentine but not sound layers of dentine beneath the lesion. This finding may have clinical implications.
authors.affiliation: Laboratoire d'Histologie, Faculté de Chirurgie Dentaire (Paris V), Montrouge, France.
authors.forename: M
authors.initials: M
authors.lastname: Goldberg
authors.forename: B
authors.initials: B
authors.lastname: Keil
mesh_terms: D000328:Adult; D000421:Alcaligenes / Q000201:enzymology*; D003731:Dental Caries / Q000378:metabolism / Q000473:pathology*; D003804:Dentin / Q000187:drug effects* / Q000648:ultrastructure; D006801:Humans; D003012:Microbial Collagenase / Q000494:pharmacology*; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged
chemical_list: D003012:Microbial Collagenase