Imaging tumors with respect to a grid coordinate system by proton magnetic resonance using lipid suppression and T2 weighting.
Experimental tumors can be located with respect to a grid coordinate system by using lipid-suppressed T2-weighted proton imaging with thick coronal slices and a plexiglass grid containing a solution of paramagnetic ions. Most normal tissues except the brain, eyes, and CNS are essentially transparent under these conditions, allowing thick sections to be rapidly searched for tumors. Use of this approach to monitor tumor growth is demonstrated.
Block
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RE
Department of Radiology, Mount Sinai Medical Center, Miami Beach, Florida 33140.
Parekh
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BC
D000818:Animals; D005260:Female; D008055:Lipids; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008325:Mammary Neoplasms, Experimental / Q000473:pathology*; D011522:Protons; D051381:Rats; D011916:Rats, Inbred F344
D008055:Lipids; D011522:Protons