title: Coexistence of multiple peptides in small intensely fluorescent (SIF) cells of inferior mesenteric ganglion of the guinea pig.
abstract: Coexistence of peptides in the small intensely fluorescent cells was demonstrated by immunocytochemistry for met-enkephalin-Arg-Gly-Leu, vasoactive intestinal polypeptide, somatostatin, neuropeptide Y and dynorphin. In the extreme example, a single cell was immunoreactive to all 5 peptides examined. Four peptides coexisted in 8% and three peptides in 13% of SIF cells. In 10% of SIF cells no peptide immunoreactivity could be detected. The most prevalent peptide was met-enkephalin (in 46% of cells), then vasoactive intestinal polypeptide (45%), somatostatin (39%), neuropeptide Y (31%) and dynorphin (24%). Met-enkephalin and vasoactive intestinal polypeptide coexisted most commonly (25%).
authors.affiliation: Department of Anatomy, Saga Medical School, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Chiba
authors.forename: S
authors.initials: S
authors.lastname: Masuko
mesh_terms: D000818:Animals; D001341:Autonomic Nervous System / Q000166:cytology / Q000378:metabolism*; D002395:Catecholamines / Q000378:metabolism*; D004399:Dynorphins / Q000378:metabolism; D004744:Enkephalin, Methionine / Q000031:analogs & derivatives / Q000378:metabolism; D006168:Guinea Pigs; D006651:Histocytochemistry; D007150:Immunohistochemistry; D008297:Male; D008643:Mesentery / Q000166:cytology / Q000294:innervation* / Q000378:metabolism; D009478:Neuropeptide Y / Q000378:metabolism; D009479:Neuropeptides / Q000378:metabolism*; D014660:Vasoactive Intestinal Peptide / Q000378:metabolism
chemical_list: D002395:Catecholamines; D009478:Neuropeptide Y; D009479:Neuropeptides; D014660:Vasoactive Intestinal Peptide; D004744:Enkephalin, Methionine; D004399:Dynorphins; C033453:enkephalin-Met, Arg(6)-Gly(7)-Leu(8)-