DDT toxicity: variations in tissue non-specific phosphomonoesterases and gluconeogenic enzymes in three teleosts.
Three fish species were exposed to a sublethal dose (0.35 mg/l) of DDT continuously for a period of 50 days and the effect of hepatic and renal acid and alkaline phosphatases, glucose-6-phosphatase and fructose-1,6-diphosphatase activities was observed at 15, 30 and 45 days. Exposure to DDT at 15 days led to the fall and increase thereafter (at 30 and 45 days) in the activities of acid phosphatase, glucose-6-phosphatase and fructose-1,6-diphosphatase in hepatic tissue, where as alkaline phosphatase in liver registered an increase at 15, 30 and 45 days DDT exposure. In renal tissue the trend of 4 phosphatases was same as that of alkaline phosphatase in the liver. The changes in these 4 phosphatases were more pronounced in C. punctatus than in G. batrachus and L. rohita.
Shaffi
S A
SA
Department of Science Regional College of Education NCERT, Bhopal, India.
Dubey
R P
RP
D000135:Acid Phosphatase / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D003634:DDT / Q000633:toxicity*; D005399:Fishes; D006597:Fructose-Bisphosphatase / Q000378:metabolism; D005943:Gluconeogenesis / Q000187:drug effects*; D005952:Glucose-6-Phosphatase / Q000378:metabolism; D007668:Kidney / Q000187:drug effects / Q000201:enzymology; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism*; D013997:Time Factors
D003634:DDT; D000469:Alkaline Phosphatase; D006597:Fructose-Bisphosphatase; D000135:Acid Phosphatase; D010744:Phosphoric Monoester Hydrolases; D005952:Glucose-6-Phosphatase