title: Spin label and microcalorimetric studies of the interaction of DNA with unilamellar phosphatidylcholine liposomes.
abstract: High-molecular DNA from chicken erythrocytes interacts with 1,2-dipalmitoylphosphatidylcholine in unilamellar liposomes, both in the presence and absence of Mg2+ ions. This interaction results in a phase separation in liposome membranes. The new phase induced by DNA and Mg2+ has a higher gel-liquid crystal phase transition temperature as measured by microcalorimetry. In the liquid crystalline state, the 16- and 5-doxyl stearic acid spin labels indicate changed local bilayer properties at the label position in the new phase.
authors.affiliation: Faculty of Sciences, P. J. Safárik University, Kosice, Czechoslovakia.
authors.forename: L
authors.initials: L
authors.lastname: Vojcíková
authors.forename: E
authors.initials: E
authors.lastname: Svajdlenka
authors.forename: P
authors.initials: P
authors.lastname: Balgavý
mesh_terms: D015060:1,2-Dipalmitoylphosphatidylcholine; D000818:Animals; D002151:Calorimetry; D002645:Chickens; D004247:DNA / Q000097:blood; D004578:Electron Spin Resonance Spectroscopy; D004912:Erythrocytes / Q000032:analysis; D008081:Liposomes; D008274:Magnesium; D013113:Spin Labels
chemical_list: D008081:Liposomes; D013113:Spin Labels; D015060:1,2-Dipalmitoylphosphatidylcholine; D004247:DNA; D008274:Magnesium