[Comparison of the effects of thyroliberin and ACTH4-7 PGP on the learning of rats during the solving of spatial orientation tasks].
The influence of TRH (100 micrograms/kg) and ACTH4-7 Pro-Gly-Pro (15 micrograms/kg and 25 micrograms/kg) involved an acceleration of the spatial learning on the 12-arm radial maze and on T-maze in rats; an increase in the number of correct choice after short (5-10 min) retention interval; and affected the working and reference spatial memory in the test of reinforced place performance. The effects of the TRH and ACTH4-7 Pro-Gly-Pro did not interfere with one another.
Chepurnova
N E
NE
Guseva
A A
AA
Efimova
E V
EV
Mart'ianov
A A
AA
Chepurnov
S A
SA
D000324:Adrenocorticotropic Hormone / Q000031:analogs & derivatives* / Q000494:pharmacology; D000818:Animals; D004347:Drug Interactions; D005247:Feeding Behavior / Q000187:drug effects; D007858:Learning / Q000187:drug effects*; D008568:Memory / Q000187:drug effects; D010446:Peptide Fragments / Q000494:pharmacology*; D011340:Problem Solving / Q000187:drug effects*; D051381:Rats; D012054:Reinforcement, Psychology; D013037:Spatial Behavior / Q000187:drug effects*; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology*
D010446:Peptide Fragments; D013973:Thyrotropin-Releasing Hormone; C048487:ACTH (4-7), Pro-Gly-Pro-; D000324:Adrenocorticotropic Hormone
Sravnenie vliianiĭ tiroliberina i AKTG4-7 PGP na obuchenie krys pri reshenii zadach na prostranstvennuiu orientatsiiu.