[Malignant lymphoma which contained EBV DNA and lacked EBNA2 antibody].
A case of non-Hodgkin malignant lymphoma which contained EBV DNA and EBNA was reported. The serum of this patient showed high titer of VCA, EA, and EBNA1 antibody but lacked EBNA2 antibody. The relation with EBV originated malignancy and defect of EBV specific antibody suggests a process of oncogenicity of this virus.
Shimakage
M
M
Hirai
K
K
Ikegami
N
N
Matsubuchi
T
T
Kawagoe
H
H
D000914:Antibodies, Viral / Q000032:analysis*; D000956:Antigens, Viral / Q000276:immunology; D004279:DNA, Viral / Q000032:analysis*; D019309:Epstein-Barr Virus Nuclear Antigens; D004854:Herpesvirus 4, Human / Q000276:immunology*; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000276:immunology* / Q000382:microbiology; D008297:Male; D008875:Middle Aged
D000914:Antibodies, Viral; D000956:Antigens, Viral; D004279:DNA, Viral; D019309:Epstein-Barr Virus Nuclear Antigens