Distribution of dynorphin B and methionine-enkephalin in the mouse hippocampus: influence of genotype.
Immunohistochemical techniques were used to localize dynorphin B and methionine-enkephalin in the mouse hippocampus. Methionine-enkephalin-like immunoreactivity was found within the somata of interneurons distributed mainly in and around the CA1 stratum pyramidale and stratum granulosum as well as in the mossy fibers. Dynorphin B appeared to be confined to the mossy fiber pathway. In addition, we observed a difference between the inbred mouse strains DBA/2 and C57BL/6 with regard to the areas of the dynorphinergic mossy fiber projections: the intra- and infrapyramidal terminal fields were larger in the latter group.
van Daal
J H
JH
Department of Animal Physiology, University of Nijmegen, The Netherlands.
Zanderink
H E
HE
Jenks
B G
BG
van Abeelen
J H
JH
D000818:Animals; D004399:Dynorphins / Q000031:analogs & derivatives* / Q000378:metabolism; D004723:Endorphins / Q000378:metabolism*; D004744:Enkephalin, Methionine / Q000378:metabolism*; D005838:Genotype; D006624:Hippocampus / Q000378:metabolism*; D007150:Immunohistochemistry; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA
D004723:Endorphins; D004744:Enkephalin, Methionine; D004399:Dynorphins; C036200:rimorphin