title: Detection of a rare allele with the pMP6d-9/MspI RFLP near the cystic fibrosis locus.
abstract: We report a rare allele detected using pMP6d-9, a probe very closely linked to cystic fibrosis (CF), on digestion with MspI. This allele has been found in normal and CF chromosomes, and therefore cannot be related to the mutation causing the disease.
authors.affiliation: Unitat de Genètica Molecular, Biomedical Research Institute, Fundació d'Investigació Santa Creu i Sant Pau, Barcelona, Spain.
authors.forename: V
authors.initials: V
authors.lastname: Nunes
authors.forename: T
authors.initials: T
authors.lastname: Casals
authors.forename: P
authors.initials: P
authors.lastname: Gallano
authors.forename: F J
authors.initials: FJ
authors.lastname: Giménez
authors.forename: J
authors.initials: J
authors.lastname: Kere
authors.forename: R
authors.initials: R
authors.lastname: Williamson
authors.forename: X
authors.initials: X
authors.lastname: Estivill
mesh_terms: D000483:Alleles; D003550:Cystic Fibrosis / Q000235:genetics*; D015342:DNA Probes; D005260:Female; D005819:Genetic Markers; D006801:Humans; D008297:Male; D010375:Pedigree; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D015342:DNA Probes; D005819:Genetic Markers