[Effects of non-lethal scalding on the density and affinity of beta adrenoreceptors in cardiac muscle in rats].
Our results indicate changes in both Bmax and KD of the beta-adrenergic receptors in the ventricular heart muscle of the rat, submitted to non-lethal scalding, even in the early posttraumatic period. The changes of heart, plasma and urine noradrenaline and adrenaline contents indicate significant increase in sympatho-adrenal activity after non-lethal scalding. The parallel changes of the beta-adrenergic receptor characteristics, which depend on the changes of catecholamines in the heart muscle and plasma only at certain time intervals after trauma, tend to preserve normal-control values.
Prostran
M
M
Institut de Pharmacologie, Faculté de Médecine, Belgrade, Yougoslavie.
Vujnov
S
S
Savic
J
J
Varagic
V M
VM
Lovric
M
M
Bacic
F
F
D000818:Animals; D002056:Burns / Q000378:metabolism; D004837:Epinephrine / Q000032:analysis / Q000378:metabolism*; D006358:Hot Temperature / Q000009:adverse effects*; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D009638:Norepinephrine / Q000032:analysis / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D011943:Receptors, Adrenergic, beta / Q000032:analysis / Q000378:metabolism*; D012867:Skin / Q000293:injuries
D011943:Receptors, Adrenergic, beta; D009638:Norepinephrine; D004837:Epinephrine
Effets de l'échaudage non létal sur la densité et l'affinité des beta-adrénocepteurs dans le muscle cardiaque du rat.