[Lyophilized membranes as a test system for analyzing the properties of neuromediator receptors and activity of neurotropic agents].
The effect of lyophilization and prolonged storage of rat brain membrane preparations on the properties of receptors of cholinergic and adrenergic neuromediator systems has been studied by the radioreceptor assay. Lyophilized membrane preparations have been shown to be highly stable as compared with fresh membranes and retain their binding properties during storage for 1 year.
Evdokimenko
S G
SG
Serebriakova
O G
OG
Zaĭtsev
S V
SV
Kurochkin
I N
IN
Zhukov
V P
VP
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D001923:Brain Chemistry / Q000187:drug effects; D005612:Freeze Drying; D051379:Mice; D009420:Nervous System / Q000187:drug effects*; D011869:Radioligand Assay / Q000379:methods; D051381:Rats; D011919:Rats, Inbred Strains; D017981:Receptors, Neurotransmitter / Q000032:analysis / Q000187:drug effects / Q000378:metabolism*; D013570:Synaptic Membranes / Q000032:analysis / Q000187:drug effects / Q000378:metabolism*; D014021:Tissue Preservation / Q000379:methods
D017981:Receptors, Neurotransmitter
Liofilizovannye membrany kak test-sistema dlia analiza svoĭstv retseptorov neĭromediatorov i aktivnosti neĭrotropnykh sredstv.