[Endogenous beta-adrenomimetic substance as a constituent of the adrenergic beta receptor blocking mechanism].
In order to reveal endogenous beta-adrenomimetic in the blood the authors proposed the biological testing of the serum and plasma on the isolated myometrium of the rat. For this purpose obsidan was used as a beta-adrenoblocker. It was shown that endogenous beta-adrenomimetic different from adrenaline was present in the blood of males, nonpregnant and pregnant females and parturients. Besides, its concentration increased in pregnancy and remained high early in labor.
Pomaskin
I N
IN
Medvedev
B I
BI
Tsirkin
V I
VI
Zakharov
V V
VV
D000293:Adolescent; D000328:Adult; D000818:Animals; D004837:Epinephrine / Q000502:physiology*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D007743:Labor, Obstetric / Q000502:physiology*; D009215:Myometrium / Q000187:drug effects / Q000502:physiology*; D011247:Pregnancy / Q000502:physiology*; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D011943:Receptors, Adrenergic, beta / Q000187:drug effects / Q000502:physiology*; D014590:Uterine Contraction / Q000187:drug effects
D011943:Receptors, Adrenergic, beta; D011433:Propranolol; D004837:Epinephrine
Endogennyĭ beta-adrenomimetik kak komponent beta-adreno- retseptornogo ingibiruiushchego mekhanizma.