title: In vitro inhibition of methionine incorporation in the dorsal bodies of Helix aspersa by synthetic FMRFamide.
abstract: 1. In in vitro conditions, synthetic FMRFamide was shown to inhibit the uptake of labelled methionine by the dorsal bodies (DB)-containing connective tissue of Helix aspersa. 2. This effect occurred at physiological concentrations and in a dose-dependent manner. 3. Among the different cell types of the explants, the DB cells preferentially incorporated the radioactive precursor. 4. These results suggest that FMRFamide plays a biological role in controlling the DB activity (protein synthesis) of Helix aspersa.
authors.affiliation: Laboratoire de Zoologie et Embryologie, UA CNRS 040687, Faculté des Sciences, Besançon, France.
authors.forename: B
authors.initials: B
authors.lastname: Griffond
authors.forename: K
authors.initials: K
authors.lastname: Mounzih
mesh_terms: D000818:Animals; D001345:Autoradiography; D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D003238:Connective Tissue / Q000378:metabolism; D004702:Endocrine Glands / Q000378:metabolism*; D019835:FMRFamide; D006372:Helix, Snails / Q000378:metabolism*; D008715:Methionine / Q000378:metabolism*; D009479:Neuropeptides / Q000494:pharmacology*
chemical_list: D009479:Neuropeptides; D019835:FMRFamide; D008715:Methionine