title: Structure and expression of an integrated human papillomavirus type 16 genome amplified in a cervical carcinoma cell line.
abstract: A cellular sequence containing the integrated human papillomavirus type 16 genome in a cervical carcinoma cell line QG-U was cloned and analysed. The transcriptionally active viral genome disrupted at the E2 and L2 open reading frames was amplified with its flanking sequences.
authors.affiliation: Department of Microbiology, School of Medicine, Chiba University, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Shirasawa
authors.forename: Y
authors.initials: Y
authors.lastname: Tomita
authors.forename: A
authors.initials: A
authors.lastname: Fuse
authors.forename: T
authors.initials: T
authors.lastname: Yamamoto
authors.forename: H
authors.initials: H
authors.lastname: Tanzawa
authors.forename: S
authors.initials: S
authors.lastname: Sekiya
authors.forename: H
authors.initials: H
authors.lastname: Takamizawa
authors.forename: B
authors.initials: B
authors.lastname: Simizu
mesh_terms: D001483:Base Sequence; D002277:Carcinoma / Q000235:genetics / Q000382:microbiology*; D002460:Cell Line; D015344:DNA Probes, HPV; D004279:DNA, Viral / Q000302:isolation & purification; D005260:Female; D005784:Gene Amplification; D005814:Genes, Viral; D006801:Humans; D008969:Molecular Sequence Data; D027383:Papillomaviridae / Q000235:genetics*; D015183:Restriction Mapping; D014158:Transcription, Genetic; D002583:Uterine Cervical Neoplasms / Q000235:genetics / Q000382:microbiology*
chemical_list: D015344:DNA Probes, HPV; D004279:DNA, Viral