Nucleus raphe obscurus (nRO) influences vagal control of gastric motility in rats.
Because the nucleus raphe obscurus (nRO) maintains a direct connection with the dorsal vagal complex in the medulla, this nucleus has the potential to influence vagal control of gastric function. Both electrical- and glutamate-induced activation of the nRO were found to enhance gastric motility and tone in the rat. The gastric responses to nRO stimulation were abolished by peripheral muscarinic blockade.
McCann
M J
MJ
Department of Physiology, Ohio State University College of Medicine, Columbus 43210.
Hermann
G E
GE
Rogers
R C
RC
D000818:Animals; D004558:Electric Stimulation; D005971:Glutamates / Q000494:pharmacology; D018698:Glutamic Acid; D008297:Male; D009119:Muscle Contraction; D011903:Raphe Nuclei / Q000502:physiology*; D051381:Rats; D013270:Stomach / Q000294:innervation* / Q000502:physiology; D014630:Vagus Nerve / Q000502:physiology*
D005971:Glutamates; D018698:Glutamic Acid