The effects of enalapril on hypertension and quality of life. A large multicenter study in Belgium.
Belgian general practitioners studied the effect of enalapril over a period of 6 months on hypertension and quality of life in 4988 patients, whose hypertensive condition remained uncontrolled by previous treatments and/or in whom this previous drug regimen was not tolerated. Blood pressure was reduced from an average of 170/101 mm Hg at the onset of the trial to 145/85.5 mm Hg after 24 weeks. The treatment with enalapril was well tolerated and tolerance improved remarkably in the patients, whose previous treatment had caused intolerance. Quality of life, determined by means of the Nottingham Health Profile questionnaire, was favourably influenced in the patients participating in this study.
de Lame
P A
PA
M.S.D. International, Rahway, N.J.
Droussin
A M
AM
Thomson
M
M
Verhaest
L
L
Wallace
S
S
D000328:Adult; D000368:Aged; D001530:Belgium; D001794:Blood Pressure / Q000187:drug effects; D004656:Enalapril / Q000627:therapeutic use*; D006305:Health Status Indicators; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D011788:Quality of Life; D013997:Time Factors
D004656:Enalapril