title: Biochemical characteristics and physiological significance of major DNA topoisomerases.
authors.affiliation: Department of Immunology and Infectious Diseases, Pfizer Central Research, Groton, Connecticut 06340.
authors.forename: J A
authors.initials: JA
authors.lastname: Sutcliffe
authors.forename: T D
authors.initials: TD
authors.lastname: Gootz
authors.forename: J F
authors.initials: JF
authors.lastname: Barrett
mesh_terms: D001419:Bacteria / Q000201:enzymology* / Q000235:genetics; D004264:DNA Topoisomerases, Type I / Q000378:metabolism* / Q000502:physiology; D004250:DNA Topoisomerases, Type II / Q000378:metabolism* / Q000502:physiology
chemical_list: D004264:DNA Topoisomerases, Type I; D004250:DNA Topoisomerases, Type II