Analytical method for the quantification of 2',3'-didehydro-3'-deoxythymidine, a new anti-human immunodeficiency virus (HIV) agent, by high-performance liquid chromatography (HPLC) and ultraviolet (UV) detection in rat and monkey plasma.
Kaul
S
S
Metabolism and Pharmacokinetics, Pharmaceutical Research, Bristol-Myers Company, Syracuse, New York 13221.
Dandekar
K A
KA
Pittman
K A
KA
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D000818:Animals; D000998:Antiviral Agents / Q000097:blood*; D002851:Chromatography, High Pressure Liquid; D015224:Dideoxynucleosides / Q000097:blood*; D008252:Macaca fascicularis; D051381:Rats; D013045:Species Specificity; D013056:Spectrophotometry, Ultraviolet; D018119:Stavudine
D000998:Antiviral Agents; D015224:Dideoxynucleosides; D018119:Stavudine