title: Investigative study of radiopharmaceuticals useful for imaging skeletal muscle injury in experimental animals.
abstract: An experimental animal model for studying skeletal muscle injury is described. Tc-99m PYP is accumulated on the skeletal muscle injury, but its uptake on the adjacent bone obscures its usefulness in delineating the extent of the muscle injury. In-111 antimyosin accumulates and delineates the extent of the skeletal muscle injury and does not accumulate on the adjacent bone. Hence, In-111 antimyosin is a good radiopharmaceutical for studying the severity and prognosis of skeletal muscle injury.
authors.affiliation: Department of Nuclear Medicine, Faculty of Medicine, Kuwait University, Safat.
authors.forename: A
authors.initials: A
authors.lastname: Owunwanne
authors.forename: A
authors.initials: A
authors.lastname: Malki
authors.forename: S
authors.initials: S
authors.lastname: Sadek
authors.forename: A
authors.initials: A
authors.lastname: el-Gazzar
authors.forename: T
authors.initials: T
authors.lastname: Yacoub
authors.forename: H M
authors.initials: HM
authors.lastname: Abdel-Dayem
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal; D011756:Diphosphates; D007205:Indium Radioisotopes; D009132:Muscles / Q000000981:diagnostic imaging / Q000293:injuries*; D009218:Myosins / Q000276:immunology*; D011817:Rabbits; D011877:Radionuclide Imaging; D013667:Technetium; D016698:Technetium Tc 99m Pyrophosphate
chemical_list: D000911:Antibodies, Monoclonal; D011756:Diphosphates; D007205:Indium Radioisotopes; D016698:Technetium Tc 99m Pyrophosphate; D013667:Technetium; D009218:Myosins