title: Patterns of endocrine secretion during sepsis.
abstract: In septic patients the clinical course of the disease is characterized by high DIT and rT3 serum concentrations as well as a low T3-syndrome. While rT3 is elevated in almost all critically ill patients, the increase in DIT is indicative of severe infection. Prolactin levels are regularly elevated in sepsis although to variable degrees. Catecholamines and vasopressin should be regarded as acute responders. The pattern of cortisol secretion is uncertain. In most situations the secretion appears to be elevated; the circadian rhythm is disturbed.
authors.affiliation: Klinik für Anästhesiologie, Krankenhaus Nordwest, Frankfurt.
authors.forename: R
authors.initials: R
authors.lastname: Dennhardt
authors.forename: H J
authors.initials: HJ
authors.lastname: Gramm
authors.forename: K
authors.initials: K
authors.lastname: Meinhold
authors.forename: K
authors.initials: K
authors.lastname: Voigt
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000378:metabolism; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004104:Diiodothyronines / Q000378:metabolism; D006728:Hormones / Q000378:metabolism*; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism; D008875:Middle Aged; D011183:Postoperative Complications; D011388:Prolactin / Q000378:metabolism; D018805:Sepsis / Q000209:etiology / Q000503:physiopathology*; D012772:Shock, Septic / Q000503:physiopathology; D013972:Thyrotropin / Q000378:metabolism; D013974:Thyroxine / Q000378:metabolism; D014284:Triiodothyronine / Q000378:metabolism; D014285:Triiodothyronine, Reverse / Q000378:metabolism; D014667:Vasopressins / Q000378:metabolism
chemical_list: D004104:Diiodothyronines; D006728:Hormones; D014284:Triiodothyronine; D014667:Vasopressins; D014285:Triiodothyronine, Reverse; D000324:Adrenocorticotropic Hormone; D011388:Prolactin; D013972:Thyrotropin; D013974:Thyroxine; D006854:Hydrocortisone