Effects of physiological increases in plasma noradrenaline on the human endocrine pancreas.
The effect of plasma noradrenaline concentrations within the physiological range (less than 5-6 nM) on the endocrine pancreas was investigated in 9 nondiabetic volunteers. Noradrenaline significantly inhibited plasma insulin levels but did not change plasma glucagon and somatostatin concentrations.
Järhult
J
J
Department of Surgery, Eksjö Hospital, Sweden.
Farnebo
L O
LO
Graffner
H
H
Holst
J
J
D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism; D002395:Catecholamines / Q000097:blood; D002851:Chromatography, High Pressure Liquid; D005260:Female; D005934:Glucagon / Q000097:blood; D006801:Humans; D007328:Insulin / Q000097:blood; D007515:Islets of Langerhans / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000097:blood*; D013004:Somatostatin / Q000097:blood
D001786:Blood Glucose; D002395:Catecholamines; D007328:Insulin; D013004:Somatostatin; D005934:Glucagon; D009638:Norepinephrine