title: Outbreak of Clostridium difficile diarrhoea in an orthopaedic unit: evidence by phage-typing for cross-infection.
abstract: In a three-week period five patients had diarrhoea in an orthopaedic unit. The first case was clinically diagnosed as pseudomembranous colitis but the causative agent was not sought. Of the remaining cases, two were Clostridium difficile positive. The outbreak then apparently ceased, but during the following several days two of seven stool samples taken at random from asymptomatic patients yielded C. difficile. Phage-typing of the isolates showed that all apparently belonged to the same strain.
authors.affiliation: Laboratorio di Analisi Chimico-Cliniche e Microbiologia, P. Palagi Hospital USL 10B, Florence, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Degl'Innocenti
authors.forename: M
authors.initials: M
authors.lastname: De Santis
authors.forename: I
authors.initials: I
authors.lastname: Berdondini
authors.forename: R
authors.initials: R
authors.lastname: Dei
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001434:Bacteriophage Typing; D003015:Clostridium Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission; D003428:Cross Infection / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission; D003967:Diarrhea / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007558:Italy; D008875:Middle Aged; D009985:Orthopedics