title: Estimation of pulsatile ocular blood flow from intraocular pressure.
abstract: A relationship has been derived between intraocular pressure and pulsatile blood flow in the eye. Measurements of intraocular pressure show a time variation that is associated with the pulsatile component of arterial pressure. Experimental results provide a means of transforming intraocular pressure changes into ocular volume changes. The eye is represented by a chamber with elastic walls, a pulsatile incoming flow of incompressible fluid (blood), and a steady outgoing flow of blood. Under these conditions, the rate of pulsatile blood flow through the eye can be approximated from the instantaneous intraocular pressure measurements. Data from a healthy human eye are used to illustrate the analysis.
authors.affiliation: Johns Hopkins University, Baltimore, MD.
authors.forename: D M
authors.initials: DM
authors.lastname: Silver
authors.forename: R A
authors.initials: RA
authors.lastname: Farrell
authors.forename: M E
authors.initials: ME
authors.lastname: Langham
authors.forename: V
authors.initials: V
authors.lastname: O'Brien
authors.forename: P
authors.initials: P
authors.lastname: Schilder
mesh_terms: D001783:Blood Flow Velocity; D005123:Eye / Q000033:anatomy & histology / Q000098:blood supply*; D006801:Humans; D007429:Intraocular Pressure; D011673:Pulsatile Flow; D012212:Rheology; D013997:Time Factors