[Ultrastructural characteristics of virus-producing lymphocytes in bovine leukemia].
The ultrastructure of peripheral lymphocytes and lymph was examined in 35 head of cattle in health and chronic lymphoid leukemia. In the latter, ultrastructural alterations were detected in the nuclei and cytoplasmic organelles. The alterations appeared as Golgi apparatus hypertrophy, mitochondrial polymorphism, myelinoid formations. There were nuclear pockets, invaginations in the nuclei of leukemic lymphocytes. A correlation was established between the number of cells having nuclear pockets and the virus production of lymphoid cells in chronic lymphoid leukemia. There is evidence that the existence of nuclear pockets along with other indicators may be useful in assessing the development of leukemias in cattle. The morphogenesis of bovine leukemia virus is presented.
Shishkov
V P
VP
Men'shikova
Z N
ZN
D000818:Animals; D002417:Cattle; D002467:Cell Nucleus / Q000648:ultrastructure; D006056:Golgi Apparatus / Q000648:ultrastructure; D001909:Leukemia Virus, Bovine / Q000502:physiology*; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000382:microbiology* / Q000473:pathology; D008196:Lymph / Q000648:ultrastructure; D008214:Lymphocytes / Q000382:microbiology / Q000648:ultrastructure*; D015388:Organelles / Q000648:ultrastructure; D012190:Retroviridae / Q000502:physiology*; D014779:Virus Replication
Ul'trastrukturnaia kharakteristika virusprodutsiruiushchikh limfotsitov pri leĭkoze krupnogo rogatogo skota.