title: The Southmead perineal suture study. A randomized comparison of suture materials and suturing techniques for repair of perineal trauma.
abstract: Commonly used suture materials and techniques for perineal repair following vaginal delivery were compared in a randomized controlled trial involving 1574 women. Three comparisons were made using a modified factorial design. In the comparison of teflon-coated polyglycolic acid (Dexon plus) with chromic catgut for repair of the vagina and deep perineal tissues there was no clear difference other than less short-term analgesia being required in association with polyglycolic acid. Outcome was also similar after skin repair with either polyglycolic acid or chromic catgut or silk, although silk repair required more packets of material and was associated with delay in resuming sexual intercourse; polyglycolic acid was more likely to need removal than chromic catgut but it appeared to reduce the need for resuturing. There was no clear difference between continuous subcuticular and interrupted transcutaneous sutures for repair of perineal skin.
authors.affiliation: Department of Obstetrics and Gynaecology, Southmead Hospital, Westbury-on-Trym, Bristol.
authors.forename: K
authors.initials: K
authors.lastname: Mahomed
authors.forename: A
authors.initials: A
authors.lastname: Grant
authors.forename: H
authors.initials: H
authors.lastname: Ashurst
authors.forename: D
authors.initials: D
authors.lastname: James
mesh_terms: D000328:Adult; D000700:Analgesics / Q000627:therapeutic use; D002398:Catgut; D005260:Female; D006801:Humans; D019476:Insect Proteins; D007743:Labor, Obstetric; D010502:Perineum / Q000293:injuries / Q000601:surgery*; D011100:Polyglycolic Acid; D011247:Pregnancy; D011379:Prognosis; D011506:Proteins; D016032:Randomized Controlled Trials as Topic; D047011:Silk; D013536:Suture Techniques; D013537:Sutures; D014621:Vagina / Q000293:injuries / Q000601:surgery
chemical_list: D000700:Analgesics; D019476:Insect Proteins; D011506:Proteins; D047011:Silk; D011100:Polyglycolic Acid