title: [The importance of food and drug plant factors in the combined treatment of patients with type-II diabetes mellitus].
abstract: A study was made of the effect of natural (vegetable dish) and refined (food methylcellulose--MC-100 and citrus pectin) vegetable fibers and Arfazetin (antidiabetic species, USSR) on the level of glucose, immunoreactive insulin (IRI), C-peptide, glucagon and gastrin in the blood of 41 patients with type II diabetes mellitus. These parameters were investigated on an empty stomach, 1, 2 and 4 h after breakfast I with a standard set of foodstuffs and minimum content of nutritive fibers. Similar investigations were conducted after intake of the same breakfast I in combination with various vegetable components. All the vegetable factors under study were shown to contribute to a decrease in a value of a glycemic rise noted after food intake. A vegetable dish and Arfazetin equally caused a significant rise of IRI secretion and C-peptide 60-90 min. after breakfast. MC-100 and particularly pectin decreased IRI and C-peptide secretion. There was a significant rise of gastrin secretion 1, 2 and 4 h when pectin was added to breakfast. When Arfazetin, a vegetable dish and MC-100 were added to breakfast I, a tendency to a rise of serum gastrin was observed 1 h after breakfast. The level of IRG during investigations with vegetable components did not differ from the results of investigations without these components.
authors.forename: V D
authors.initials: VD
authors.lastname: Korotkova
authors.forename: A A
authors.initials: AA
authors.lastname: Perelygina
authors.forename: M B
authors.initials: MB
authors.lastname: Antsiferov
authors.forename: A M
authors.initials: AM
authors.lastname: Lobanova
authors.forename: T E
authors.initials: TE
authors.lastname: Trumpe
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D002096:C-Peptide / Q000097:blood; D003131:Combined Modality Therapy; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000628:therapy*; D003927:Diet, Diabetic; D004043:Dietary Fiber / Q000627:therapeutic use; D005755:Gastrins / Q000097:blood; D005934:Glucagon / Q000097:blood; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007330:Insulin Antibodies / Q000032:analysis; D008875:Middle Aged; D010936:Plant Extracts / Q000627:therapeutic use*
chemical_list: D001786:Blood Glucose; D002096:C-Peptide; D004043:Dietary Fiber; D005755:Gastrins; D007004:Hypoglycemic Agents; D007330:Insulin Antibodies; D010936:Plant Extracts; C057858:arfazetin; D005934:Glucagon
vernacular_title: Znachenie pishchevykh i lekarstvennykh rastitel'nykh faktorov v kompleksnom lechenii bol'nykh sakharnym diabetom II tipa.