[Lung function following irradiation in pediatric cancer patients].
Lung function tests were performed in 22 children and juveniles who had received radiotherapy to the lungs, an average of 9.5 years previously, for tumour (14 with Hodgkin's disease [aged 7-22 years], 4 with malignant non-Hodgkin lymphoma [aged 6-14 years], 3 with Wilms tumour [4-6 years], and one with Ewing's sarcoma [aged 16 years]). All three patients who, as young children, had had radiotherapy to both lungs because of a Wilms tumour with multiple lung metastases had restrictive disorders of lung function. Four of 12 after treatment of Hodgkin's disease and one of two after malignant non-Hodgkin lymphoma and extensive thoracic irradiation developed a restrictive disorder of pulmonary function. But all four patients who had irradiation restricted to the mediastinum had normal lung functions.
Huber
A
A
Kinderklinik, Universität Mainz.
Gutjahr
P
P
Kleinheisterkamp
U
U
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D006689:Hodgkin Disease / Q000503:physiopathology / Q000532:radiotherapy; D006801:Humans; D007680:Kidney Neoplasms / Q000503:physiopathology / Q000532:radiotherapy; D008168:Lung / Q000503:physiopathology / Q000528:radiation effects*; D008175:Lung Neoplasms / Q000503:physiopathology / Q000532:radiotherapy / Q000556:secondary; D008228:Lymphoma, Non-Hodgkin / Q000503:physiopathology / Q000532:radiotherapy; D009369:Neoplasms / Q000503:physiopathology / Q000532:radiotherapy*; D012129:Respiratory Function Tests; D012512:Sarcoma, Ewing / Q000503:physiopathology / Q000532:radiotherapy; D013997:Time Factors; D009396:Wilms Tumor / Q000503:physiopathology / Q000532:radiotherapy
Lungenfunktion nach Bestrahlung bei pädiatrisch-onkologischen Patienten.