[Objective assessment of biological aging in the human: results].
From a population sample of 139 healthy persons, six specially selected aging parameters were tested for their significance to vitality, by means of four mathematical models referring to the concept of vitality. As reference values, tm, is the age expressed in years when maximal vitality occurs, and the aging constant is beta, also known as an aging factor. Our results for tm extended from 16.6 to 39.6 years, depending on the respective mathematical model applied. We find a similar characteristic for the beta-values. A comparison with results in other publications on the subject, obtained by processing a considerably larger number of variables than we did, underlined the utility of our parameters. This is also shown by the quality of results we obtained by regression analysis, by the adjustment to the functions of the vitality concept and by the simplicity of the required laboratory methods of analysis.
Ruiz-Torres
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A
Instituto Universitario de Investigación Gerontológica y Metabólica de la Universidad Autónoma de Madrid, Spain.
Agudo
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A
Holzenberger
M
M
Beier
W
W
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D001830:Body Surface Area; D000242:Cyclic AMP / Q000097:blood; D005260:Female; D006305:Health Status Indicators; D006306:Health Surveys; D006801:Humans; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D010446:Peptide Fragments / Q000097:blood; D011347:Procollagen / Q000097:blood; D012737:Sex Factors; D013739:Testosterone / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D008077:Lipoproteins, LDL; D010446:Peptide Fragments; D011347:Procollagen; C041876:procollagen Type III-N-terminal peptide; D014284:Triiodothyronine; D013739:Testosterone; D000242:Cyclic AMP
Zur Objektivierung des biologischen Alters des Menschen: Ergebnisse.