title: [Condylomata acuminata gigantea with detection of HPV-6-DNA. A case report with adjuvant systemic IFN-gamma therapy].
abstract: A case history of a 65-year-old man with giant condylomata (Buschke-Loewenstein tumour) of 30 years' duration is presented. The lesions were histologically confirmed, there were no signs of metastatic spread. HPV 6a DNA has been identified in Buschke-Loewenstein tumours and in different types of papilloma. After surgical removal in several sessions and treatment with gamma interferon by subcutaneous injection into the abdominal skin the patient has remained almost free of lesions.
authors.affiliation: Universitäts-Hautklinik Tübingen.
authors.forename: G
authors.initials: G
authors.lastname: Fierlbeck
authors.forename: G
authors.initials: G
authors.lastname: Rassner
mesh_terms: D000368:Aged; D003131:Combined Modality Therapy; D003218:Condylomata Acuminata / Q000473:pathology / Q000628:therapy*; D004279:DNA, Viral / Q000032:analysis*; D005834:Genital Neoplasms, Male / Q000473:pathology / Q000628:therapy*; D006801:Humans; D007370:Interferon Type I / Q000008:administration & dosage; D007371:Interferon-gamma / Q000008:administration & dosage*; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000628:therapy*; D027383:Papillomaviridae / Q000302:isolation & purification*; D012867:Skin / Q000473:pathology; D014412:Tumor Virus Infections / Q000473:pathology / Q000628:therapy*
chemical_list: D004279:DNA, Viral; D007370:Interferon Type I; D007371:Interferon-gamma
vernacular_title: Condylomata acuminata gigantea mit Nachweis von HPV-6-DNA. Fallbericht mit adjuvanter systemischer IFN-gamma-Therapie.