title: Pulmonary complications in lead miners.
abstract: We carried out a study to assess the prevalence of respiratory disease in lead miners and to investigate the roles of silica and lead. We used a questionnaire for symptoms and examinations for signs of respiratory disease, chest roentgenograms, and spirometric study in 45 lead miners. Six underwent bronchoscopy and transbronchial lung biopsy (TBB) and five lung lead analysis. Lung lead levels from five patients with no occupational lead exposure were obtained for comparison. Results showed restriction in five of 45 and reticulonodular opacities in 16 of 45 workers. Squamous metaplasia and other histopathologic changes were observed, although silicotic nodules were absent by TBB. Lung lead levels above those of control subjects were observed in four of five lead miners. These findings show that lead miners are at risk for lung disease. Although silica is a likely cause, elevated lung lead content found in these miners merits further investigation.
authors.affiliation: Pulmonary Unit, Massachusetts General Hospital, Boston 02114.
authors.forename: M R
authors.initials: MR
authors.lastname: Masjedi
authors.forename: N
authors.initials: N
authors.lastname: Estineh
authors.forename: M
authors.initials: M
authors.lastname: Bahadori
authors.forename: M
authors.initials: M
authors.lastname: Alavi
authors.forename: N L
authors.initials: NL
authors.lastname: Sprince
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy; D003430:Cross-Sectional Studies; D006801:Humans; D007492:Iran; D007854:Lead / Q000009:adverse effects*; D007855:Lead Poisoning / Q000209:etiology; D008168:Lung / Q000032:analysis; D008297:Male; D008875:Middle Aged; D008906:Mining; D011009:Pneumoconiosis / Q000453:epidemiology / Q000209:etiology*; D012307:Risk Factors; D012822:Silicon Dioxide / Q000032:analysis; D012829:Silicosis / Q000209:etiology
chemical_list: D007854:Lead; D012822:Silicon Dioxide