Chondroid syringoma associated with hidrocystoma-like changes. Possible differentiation into eccrine gland. A histologic, immunohistochemical and electron microscopic study.
A case of chondroid syringoma associated with hidrocystoma-like changes was investigated by histology, immunohistochemistry and electron microscopy. Chondroid syringoma was histologically compatible with apocrine mixed tumor, and hidrocystoma-like changes did not fulfill diagnostic criteria of either eccrine hidrocystoma or apocrine hidrocystoma. However, epithelial cellular elements composing both chondroid syringoma and hidrocystoma-like changes suggested, immunohistochemically and electron microscopically, differentiation into eccrine gland. The lesions of both had an apparent transition of ductal structures of chondroid syringoma into hidrocystoma-like changes. Therefore, chondroid syringoma and hidrocystoma-like changes in this case may be organized as a peculiar type of cutaneous appendage tumor differentiating toward eccrine gland.
Mihara
M
M
Department of Dermatology, Tottori University School of Medicine, Yonago, Japan.
D006607:Adenoma, Sweat Gland / Q000276:immunology / Q000378:metabolism / Q000473:pathology*; D000328:Adult; D002272:Carcinoembryonic Antigen / Q000378:metabolism; D004439:Eccrine Glands / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008854:Microscopy, Electron; D009418:S100 Proteins / Q000378:metabolism; D012878:Skin Neoplasms / Q000276:immunology / Q000378:metabolism / Q000473:pathology*; D013544:Sweat Gland Neoplasms / Q000276:immunology / Q000378:metabolism / Q000473:pathology*
D002272:Carcinoembryonic Antigen; D009418:S100 Proteins