Dopamine, the kidney and essential hypertension.
The evidence for dopamine as an intrarenal natriuretic hormone is reviewed. Some patients with essential hypertension may have an uncoupling of the sodium to dopamine relationship in the kidney and their blood pressures may respond particularly well to dopaminergic agonists.
Lee
M R
MR
University Department of Clinical Pharmacology, Royal Infirmary, Edinburgh, Scotland.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D004298:Dopamine / Q000502:physiology*; D015259:Dopamine Agents / Q000494:pharmacology; D006801:Humans; D006973:Hypertension / Q000378:metabolism / Q000503:physiopathology*; D007668:Kidney / Q000503:physiopathology*; D007687:Kidney Tubules, Proximal / Q000166:cytology / Q000502:physiology
D015259:Dopamine Agents; D004298:Dopamine