title: Adenovirus type 7 infections in children in New South Wales, Australia.
abstract: This study describes our experience of adenovirus type 7 infection in children in New South Wales, Australia. Some aspects of the epidemiology of the infection are also recorded. A community outbreak, a hospital-ward outbreak, sporadic cases, and data from a centralised registry are described. Results of genome-type identification using restriction endonucleases are given. Adenovirus type 7b infection was associated with significant mortality and points to the need, previously expressed, for an adequate vaccine for high-risk infants. Continued surveillance of adenovirus type 7 infections worldwide is necessary to identify genome types so that appropriate vaccines can be developed.
authors.affiliation: Department of Virology, Royal Alexandra Hospital for Children, Camperdown, Australia.
authors.forename: L M
authors.initials: LM
authors.lastname: de Silva
authors.forename: P
authors.initials: P
authors.lastname: Colditz
authors.forename: G
authors.initials: G
authors.lastname: Wadell
mesh_terms: D000257:Adenoviridae Infections / Q000453:epidemiology*; D000258:Adenovirus Infections, Human / Q000453:epidemiology* / Q000382:microbiology; D000260:Adenoviruses, Human / Q000032:analysis / Q000235:genetics; D000328:Adult; D002675:Child, Preschool; D004262:DNA Restriction Enzymes; D004196:Disease Outbreaks; D005260:Female; D005838:Genotype; D006801:Humans; D007223:Infant; D008297:Male; D009517:New South Wales / Q000453:epidemiology
chemical_list: D004262:DNA Restriction Enzymes