Combined hepatocellular-cholangiocarcinoma associated with dermatomyositis.
A 56 year old female developed combined hepatocellular cholangiocarcinoma associated with dermatomyositis. Serum tumour markers except for carbohydrate antigen (CA 19-9; 6400 ng/ml) were within normal range. Despite extensive chemotherapy, no clinical response was obtained and the patient's course deteriorated after 4 months. Macroscopically, the liver was mainly occupied by hepatocellular carcinoma but cholangiocarcinoma was found in the hilum. This is the first case of a rare association of combined hepatocellular-cholangiocarcinoma and dermatomyositis.
Horie
Y
Y
Second Department of Internal Medicine, Tottori University School of Medicine, Yonago, Japan.
Yamada
M
M
Nakai
K
K
Kawasaki
H
H
Hirayama
C
C
Matsui
K
K
Kambe
N
N
Shimao
S
S
D002759:Adenoma, Bile Duct / Q000150:complications* / Q000473:pathology; D006528:Carcinoma, Hepatocellular / Q000150:complications* / Q000473:pathology; D003882:Dermatomyositis / Q000150:complications*; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000150:complications* / Q000473:pathology; D008875:Middle Aged