Nutrient balance and obesity: an approach to control of food intake in humans.
This article has examined the regulated systems that control nutrient balance. From this analysis, the following conclusions may be suggested: 1. Each nutrient is regulated separately in a feedback system. 2. The control of glucose is regulated by the size of the glycogen stores; the size of the fat depots, by the rate of hepatic fatty acid oxidation; and protein, by the size of the protein depots. 3. Obesity can occur as a result of hyperphagia or from repartitioning the deposition of nutrients. In either case, there is a relative or absolute reduction in the activity of the sympathetic nervous system, requiring adequate levels of circulating corticosteroids.
Bray
G A
GA
Section of Diabetes and Clinical Nutrition, University of Southern California, USC/LAC School of Medicine.
D001835:Body Weight; D001921:Brain / Q000503:physiopathology; D004064:Digestive System / Q000503:physiopathology; D004435:Eating; D005246:Feedback; D006728:Hormones / Q000502:physiology; D006801:Humans; D018377:Neurotransmitter Agents / Q000502:physiology; D009747:Nutritional Physiological Phenomena; D009765:Obesity / Q000503:physiopathology*
D006728:Hormones; D018377:Neurotransmitter Agents