[Animal experiment studies of the effect of the hazardous substance carbon tetrachloride on peripheral nerves].
The deleterious effects of Carbon Tetrachloride, widely used industrially, on the peripheral nervous system was investigated by experimentation on rabbits. Long-term infusion simulated various conditions of exposure to obtain pharmacological and electroneurographic data. Tetrachlorethen is shown to induce reversible dysfunctions of the peripheral nervous system depending on the degree of concentration. The mode of molecular action remains open. Our results are compared with references in existing literature.
Wagner
A
A
Klinik für Neurologie Karl-Marx-Universität Leipzig.
Müller
C
C
Rehorek
A
A
D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000503:physiopathology*; D004305:Dose-Response Relationship, Drug; D004558:Electric Stimulation; D007262:Infusions, Intravenous; D009046:Motor Neurons / Q000187:drug effects; D010525:Peripheral Nerves / Q000187:drug effects* / Q000503:physiopathology; D011817:Rabbits; D012584:Sciatic Nerve / Q000187:drug effects; D009435:Synaptic Transmission / Q000187:drug effects*
Tierexperimentelle Untersuchungen zur Schadstoffwirkung von Tetrachlorethen auf den peripheren Nerven.