title: Precursor lesions of oesophageal cancer in young people in a high-risk population in China.
abstract: Young people (15-26 years) were selected from households in a population in China at high risk of oesophageal cancer on the basis of whether a case of oesophageal cancer had (166 participants) or had not (372 participants) occurred in a first-degree relative. In an endoscopic survey 43.5% of the male subjects and 35.9% of the female subjects showed histological signs of chronic oesophagitis. The presence of these precursor lesions was significantly associated in a multivariate logistic model with consumption of burning hot beverages, a family history of oesophageal cancer (including second-degree relatives), infrequent consumption of fresh fruit, and infrequent consumption of dietary staples other than maize.
authors.affiliation: German Cancer Research Centre, Institute of Epidemiology and Biometry, Heidelberg.
authors.forename: J
authors.initials: J
authors.lastname: Wahrendorf
authors.forename: J
authors.initials: J
authors.lastname: Chang-Claude
authors.forename: Q S
authors.initials: QS
authors.lastname: Liang
authors.forename: Y G
authors.initials: YG
authors.lastname: Rei
authors.forename: N
authors.initials: N
authors.lastname: Muñoz
authors.forename: M
authors.initials: M
authors.lastname: Crespi
authors.forename: R
authors.initials: R
authors.lastname: Raedsch
authors.forename: D
authors.initials: D
authors.lastname: Thurnham
authors.forename: P
authors.initials: P
authors.lastname: Correa
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D002681:China / Q000453:epidemiology; D002908:Chronic Disease; D004938:Esophageal Neoplasms / Q000453:epidemiology* / Q000209:etiology / Q000235:genetics / Q000473:pathology; D004941:Esophagitis / Q000150:complications / Q000453:epidemiology* / Q000473:pathology; D004945:Esophagoscopy; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D009752:Nutritional Status; D011230:Precancerous Conditions / Q000453:epidemiology* / Q000473:pathology; D015995:Prevalence; D012307:Risk Factors; D012494:Sampling Studies; D011795:Surveys and Questionnaires