Nonangiogenic and nonlymphomatous sarcomas of the canine spleen: 57 cases (1975-1987).
The case records of and histopathologic findings in 57 dogs with nonangiogenic and nonlymphomatous splenic sarcomas were reviewed. Splenic neoplasms in these dogs included leiomyosarcoma, fibrosarcoma, undifferentiated sarcoma, liposarcoma, osteosarcoma, chondrosarcoma, myxosarcoma, rhabdomyosarcoma, and fibrous histiocytoma. The clinical signs associated with splenic sarcoma included anorexia or decreased appetite, abdominal distention, polydipsia, lethargy, vomiting, weight loss, and weakness. An abdominal mass was detected in 86% of the dogs by use of abdominal palpation (63%), and/or abdominal radiography (74%). The diagnosis was based on histopathologic findings in the spleen. Abdominal exploratory surgery was performed on 43 of the 57 dogs. Twenty-seven dogs were treated by splenectomy, and 16 were euthanatized at the time of surgery because of widespread metastatic lesions. Of the 14 dogs on which surgery was not performed, 11 were euthanatized on the basis of results of preoperative diagnostic tests, and the remaining 3 dogs had splenic neoplasms that were incidental findings at necropsy. Of the 27 surgically treated dogs, 5 died in the immediate postoperative period, 12 died or were euthanatized within 1 year after splenectomy, and only 5 dogs survived greater than or equal to 1 year. Three dogs were lost to follow-up evaluation, and 2 were still alive 6 and 7 months after surgery. The median survival time of the 22 dogs for which survival was known was 2.5 months. The median survival time for 11 dogs with no obvious metastasis at the time of splenectomy was 9 months.(ABSTRACT TRUNCATED AT 250 WORDS)
Weinstein
M J
MJ
Department of Surgery, Foster Hospital for Small Animals, Tufts University School of Veterinary Medicine, North Grafton, MA 01536.
Carpenter
J L
JL
Schunk
C J
CJ
D000818:Animals; D002813:Chondrosarcoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary; D004283:Dog Diseases / Q000473:pathology* / Q000601:surgery; D004285:Dogs; D005260:Female; D005354:Fibrosarcoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology / Q000601:surgery / Q000662:veterinary; D007890:Leiomyosarcoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary; D008080:Liposarcoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary; D008297:Male; D009236:Myxosarcoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary; D012516:Osteosarcoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary; D011379:Prognosis; D012189:Retrospective Studies; D012208:Rhabdomyosarcoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary; D012509:Sarcoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D013156:Splenectomy / Q000662:veterinary; D013160:Splenic Neoplasms / Q000473:pathology / Q000601:surgery / Q000662:veterinary*