The structure of the chicken glutamine synthetase-encoding gene.
Complementary DNA (cDNA) and genomic clones encoding chicken glutamine synthetase (Glns) have been isolated. The nucleotide (nt) sequence of the 2728-bp cDNA specifies a 91-nt 5' untranslated sequence, a 1119-nt open reading frame, and a 1518-nt 3' untranslated sequence that contains several A + T-rich regions but lacks a canonical endonucleolytic-cleavage/polyadenylation signal. Based on sequence analysis of the cloned gene, the Glns transcription unit spans 7.0 kb and contains seven exons.
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Department of Chemistry, University of Illinois, Chicago 60680.
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D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002645:Chickens; D004247:DNA / Q000096:biosynthesis* / Q000302:isolation & purification; D005091:Exons; D005974:Glutamate-Ammonia Ligase / Q000096:biosynthesis / Q000235:genetics*; D008969:Molecular Sequence Data; D012333:RNA, Messenger / Q000096:biosynthesis; D015183:Restriction Mapping; D012160:Retina / Q000201:enzymology*
D012333:RNA, Messenger; D004247:DNA; D005974:Glutamate-Ammonia Ligase