Oocyte donation in 61 patients.
Oocyte donation was performed by gamete intrafallopian transfer in 61 women, 34 of whom were amenorrhoeic. The mean age of the donors was 32 years (range 23-38). Seventy-five treatment cycles gave 29 clinical pregnancies, of which 21 reached term, 3 continue, and 5 were lost (3 miscarriages, 1 tubal, and 1 cervical). 11 (38%) of the women who became pregnant were over 42 years old. When more than four oocytes were transferred, many of the pregnancies were multiple. 8 (38%) of the pregnancies that came to term were complicated by pre-eclamptic toxaemia. When oocytes are obtained from young women, the fertility potential is high irrespective of the recipient's age.
Serhal
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Fertility and IVF Unit, Humana Hospital Wellington and University College, London.
Craft
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D000286:Administration, Sublingual; D000328:Adult; D000375:Aging / Q000187:drug effects; D010064:Embryo Implantation; D004967:Estrogens / Q000008:administration & dosage / Q000494:pharmacology; D005260:Female; D015181:Gamete Intrafallopian Transfer; D006801:Humans; D007231:Infant, Newborn; D008423:Maternal Age; D008597:Menstrual Cycle / Q000187:drug effects; D008875:Middle Aged; D009865:Oocytes; D010062:Ovulation Induction / Q000379:methods; D011225:Pre-Eclampsia / Q000150:complications; D011247:Pregnancy; D018566:Pregnancy, High-Risk; D011272:Pregnancy, Multiple; D011374:Progesterone
D004967:Estrogens; D011374:Progesterone