[Behavioral effects in mice exposed to the prolonged action of cadmium compound and zinc compound].
The aim of the present paper was to determine the effect of cadmium and zinc on the central nervous system in the experimental animals. The animals were given intraperitoneally the solution of cadmium and zinc chloride for 30 days. The behaviour of the mice was being observed in the test of the coordination of movements, the cognitive activity, the spontaneous motility, the motility in the straight rod test and the effect of the examined compounds on the temperature of the animal body was examined. Together with the dose and exposure time increase the cumulative action of cadmium compound was showed, resulting in the inhibiting effect on the central nervous system. The competitive action of zinc compound in relation to the toxic action of cadmium compound was revealed after the administration of the minimal doses.
Wójcik
A
A
Burek
G
G
Dudek
M
M
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D002104:Cadmium / Q000494:pharmacology*; D002490:Central Nervous System / Q000187:drug effects*; D002712:Chlorides / Q000494:pharmacology*; D004347:Drug Interactions; D007274:Injections, Intraperitoneal; D008297:Male; D051379:Mice; D015032:Zinc / Q000494:pharmacology*; D017967:Zinc Compounds
D002712:Chlorides; D017967:Zinc Compounds; D002104:Cadmium; C016837:zinc chloride; D015032:Zinc
Behawioralne efekty u myszy poddanych przewlekłej ekspozycji na zwiazek kadmu i zwiazek cynku.