Nifedipine-induced hypotension and mesenteric ischemia.
We have presented a case in which nifedipine-induced hypotension in a patient receiving beta blocker and nitrate therapy precipitated mesenteric angina, leading to emergency exploratory celiotomy. Although paradoxic angina is an unusual complication of this antianginal therapy, it should be considered in any patient who has acute abdominal pain and hypotension while receiving this therapeutic regimen.
Goglin
W K
WK
Anesthesia and Operative Service, Brooke Army Medical Center, Fort Sam Houston, Tex. 78234.
Elliott
B M
BM
Deppe
S A
SA
D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage; D002122:Calcium Chloride / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006439:Hemodynamics; D006801:Humans; D007022:Hypotension / Q000139:chemically induced* / Q000188:drug therapy; D007511:Ischemia / Q000139:chemically induced* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000008:administration & dosage / Q000009:adverse effects*; D009566:Nitrates / Q000008:administration & dosage; D013152:Splanchnic Circulation / Q000187:drug effects*
D000319:Adrenergic beta-Antagonists; D009566:Nitrates; D009543:Nifedipine; D002122:Calcium Chloride