I elements of Drosophila melanogaster generate specific chromosomal rearrangements during transposition.
We report a detailed molecular analysis of three chromosomal rearrangements, which have been produced during I-R hybrid dysgenesis in Drosophila melanogaster. They all disrupt the yellow gene. One of them is a deletion; the other two are inversions, which may be interpreted as the results of recombination events between I elements inserted at their break points. These events appear to occur at the time of transposition and involve integrating rather than resident I elements. They are produced by a mechanism very similar to homologous ectopic recombination.
Busseau
I
I
Laboratoire de Génétique, Université Blaise Pascal, Aubière, France.
Pelisson
A
A
Bucheton
A
A
D000818:Animals; D001345:Autoradiography; D001483:Base Sequence; D002872:Chromosome Deletion; D007446:Chromosome Inversion; D003001:Cloning, Molecular; D004252:DNA Mutational Analysis; D004251:DNA Transposable Elements; D004331:Drosophila melanogaster / Q000235:genetics*; D004587:Electrophoresis, Agar Gel; D004926:Escherichia coli / Q000235:genetics; D005796:Genes; D008969:Molecular Sequence Data; D009693:Nucleic Acid Hybridization; D015183:Restriction Mapping
D004251:DNA Transposable Elements