title: Serum beta 2-microglobulin before and after renal and heart allotransplantation and in infection.
abstract: beta 2-microglobulin (beta 2-m) serum levels were significantly elevated in patients waiting for kidney transplantation. The levels decreased after successful transplantation, even when they were never as low as in a control group of healthy blood donors. A higher amount of serum (s-) beta 2-m was observed also in heart transplant recipients. A significant reincrease in s-beta 2-m occurred during rejection of renal allograft and during CMV and EBV infection. The levels of s-beta 2-m were higher in patients infected with CMV than in those infected with EBV.
  
  
  BACKGROUND
  beta 2-m = beta 2-microglobulin, s-beta 2-m = serum beta 2-microglobulin, CMV = cytomegalovirus, EBV = Epstein-Barr virus.
authors.affiliation: Institute for Clinical and Experimental Medicine, Prague.
authors.forename: L
authors.initials: L
authors.lastname: Korcáková
authors.forename: J
authors.initials: J
authors.lastname: Svobodová
authors.forename: E
authors.initials: E
authors.lastname: Sedlácková
authors.forename: J
authors.initials: J
authors.lastname: Kaslík
authors.forename: J
authors.initials: J
authors.lastname: Kaslíková
authors.forename: J
authors.initials: J
authors.lastname: Horák
authors.forename: J
authors.initials: J
authors.lastname: Fabián
authors.forename: V
authors.initials: V
authors.lastname: Kocandrle
mesh_terms: D003586:Cytomegalovirus Infections / Q000097:blood / Q000209:etiology; D006084:Graft Rejection; D016027:Heart Transplantation; D006566:Herpesviridae Infections / Q000097:blood / Q000209:etiology; D004854:Herpesvirus 4, Human; D006801:Humans; D016030:Kidney Transplantation; D011183:Postoperative Complications; D006435:Renal Dialysis; D014777:Virus Diseases / Q000097:blood* / Q000209:etiology; D001613:beta 2-Microglobulin / Q000032:analysis*
chemical_list: D001613:beta 2-Microglobulin