[Bacteriostatic and bactericidal study of rifabutine and clofazimine in combination against Mycobacterium avium-intracellulare and Mycobacterium xenopi].
The authors have tested the sensibility to rifabutine and clofazimine of seventeen strains of M. avium and eleven strains of M. xenopi. They compared the ability of these and other antimicrobial agents ciprofloxacin, amikacin and erythromycin alone or in combinations to inhibit the growth of strains of the M. avium complex and of M. xenopi. The purpose of this investigation was also to examine the bactericidal action of these antimicrobial agents and to determine the ability of combinations to kill strains of M. avium and M. xenopi.
Gevaudan
M J
MJ
Laboratoire de Microbiologie, Hygiène et Epidémiologie Hospitalière, Hôpital Salvator, Marseille.
Mallet
M N
MN
Bollet
C
C
Gulian
C
C
de Micco
P
P
D000583:Amikacin / Q000494:pharmacology; D002939:Ciprofloxacin / Q000494:pharmacology; D002991:Clofazimine / Q000494:pharmacology*; D004359:Drug Therapy, Combination; D004917:Erythromycin / Q000494:pharmacology; D006801:Humans; D009161:Mycobacterium / Q000187:drug effects*; D015269:Mycobacterium avium Complex / Q000187:drug effects*; D017828:Rifabutin; D012294:Rifamycins / Q000494:pharmacology*
D012294:Rifamycins; D017828:Rifabutin; D002939:Ciprofloxacin; D004917:Erythromycin; D000583:Amikacin; D002991:Clofazimine
Etude bactériostatique et bactéricide de la rifabutine et de la clofazimine en association vis-à-vis de Mycobacterium avium-intracellulare et de Mycobacterium xenopi.