title: Prevalence of diabetes and impaired glucose tolerance in rural Tanzania.
abstract: The prevalence of diabetes mellitus and impaired glucose tolerance (IGT) was assessed by use of WHO diagnostic criteria in 6299 Africans aged 15 years and above living in six villages in Tanzania. 0.87% (1.1% male, 0.68% female) had diabetes and 7.8% (6.9% male, 7.7% female) had IGT. Prevalence rates were 1.1% and 8.4%, respectively, when age-adjusted to the USA population. Only 7 (13.5%) of the 53 individuals with diabetes had been known to have the disorder; 34 (74%) of the other 46 were symptom-free. Mean age was 54 (SD 20) for diabetic subjects and 37 (17) years for the whole population. Diabetes and IGT rates did not differ significantly between villages despite geographical, socioeconomic, and dietary differences. Diabetes rates increased modestly with age and body mass index (BMI). Fasting blood glucose (FBG) levels did not rise significantly with age but correlated positively with systolic blood pressure (BP) and negatively with haemoglobin concentration (Hb) and BMI. The 2 hour post-glucose load blood glucose values correlated positively with age, sex, and systolic BP and negatively with Hb. Diabetes is less prevalent in rural Africa than in developed countries, even when age has been corrected for. This difference is probably related to body weight, diet, and exercise.
authors.affiliation: Department of Medicine, Muhimbili Medical Centre, Tanzania.
authors.forename: D G
authors.initials: DG
authors.lastname: McLarty
authors.forename: A B
authors.initials: AB
authors.lastname: Swai
authors.forename: H M
authors.initials: HM
authors.lastname: Kitange
authors.forename: G
authors.initials: G
authors.lastname: Masuki
authors.forename: B L
authors.initials: BL
authors.lastname: Mtinangi
authors.forename: P M
authors.initials: PM
authors.lastname: Kilima
authors.forename: W J
authors.initials: WJ
authors.lastname: Makene
authors.forename: L M
authors.initials: LM
authors.lastname: Chuwa
authors.forename: K G
authors.initials: KG
authors.lastname: Alberti
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D001835:Body Weight; D003920:Diabetes Mellitus / Q000097:blood / Q000453:epidemiology*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D012423:Rural Health / Q000639:trends; D012494:Sampling Studies; D012737:Sex Factors; D013636:Tanzania
chemical_list: D001786:Blood Glucose