[Effect of stimulation of adrenergic beta receptors on electrophysiologic properties of the bundle of Kent in patients with intermittent Wolff-Parkinson-White syndrome].
In 15 patients with intermittent ventricular preexcitation symptoms the effect of intravenously administered dobutamine (10 mcg/kg b.w./min) on the ecg tracing, effective atrial, a-v nodal and Kent bundle refractions as well as the incidence of cardiac arrhythmias were assessed basing on results of the electrophysiologic examination. Pharmacological stimulation of the adrenergic system resulted in highly statistically significant shortening of examined refraction periods (p less than 0,02 for effective Kent bundle refraction and p less than 0,001 for the rest parameters) and improved the conduction via the accessory pathway as well as exacerbated cardiac arrhythmias.
Molenda
W
W
Telichowski
C
C
Petruk
J
J
Góral
J
J
Banasiak
W
W
Metner
E
E
D000328:Adult; D004280:Dobutamine / Q000494:pharmacology*; D005260:Female; D006329:Heart Conduction System / Q000187:drug effects* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011943:Receptors, Adrenergic, beta / Q000187:drug effects* / Q000502:physiology; D013268:Stimulation, Chemical; D014927:Wolff-Parkinson-White Syndrome / Q000503:physiopathology*
D011943:Receptors, Adrenergic, beta; D004280:Dobutamine
Wpływ stymulacji receptorów beta-adrenergicznych na właściwości elektrofizjologiczne peczka Kenta u chorych z intermitujacym zespołem Wolffa-Parkinsona-White'a.