[Molar pregnancy (primary or recurrent?)].
A peculiar case of gestational trophoblastic disease is described. A 24 year old female with former history of three molar pregnancies, spontaneous abortion and anembryoic pregnancy was admitted because of a newly diagnosed hydatiform mole (ex novo). After uterine curettage followed by a low oral dose of methotrexate (0.5 mg/kg/day) for five days. The HCG levels determined in plasma by beta-HCG- radioinmmunoassay, became negative until four months of follow3 up. An intrauterine device was installed. She resumed HCG positivity a year later and a histerectomy was performed. A post-surgical diagnosis of invasive mole was made. Since the possibility of intercurrent pregnancy was lowered by the presence of a intrauterine device, we assumed that trophoblastic transformation into an invasive mole adopted a sort of dormant period before its resurge (resurrection) independently either from curettage of chemotherapy.
Ayala
A
A
Aizpuru
E
E
Tovar
J M
JM
D000328:Adult; D006063:Chorionic Gonadotropin / Q000097:blood*; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000097:blood* / Q000235:genetics; D002820:Hydatidiform Mole, Invasive / Q000097:blood* / Q000235:genetics; D009378:Neoplasms, Multiple Primary / Q000097:blood* / Q000235:genetics; D010375:Pedigree; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000097:blood* / Q000235:genetics
D006063:Chorionic Gonadotropin
Embarazo molar (ex novo aut resurrectio).