Dopamine receptors: classification, properties and drug development.
1. The pharmacology, biochemistry and structure-activity relationships pertinent to the D1 and D2 subtypes of dopamine receptors are reviewed. 2. Recent advances in receptor purification and our understanding of the secondary messenger systems involved are presented. 3. D1 and D2 receptors of central nervous, endocrine and peripheral systems are identical.
Beart
P M
PM
University of Melbourne, Clinical Pharmacology and Therapeutics Unit, Austin Hospital, Heidelberg, Victoria, Australia.
D000818:Animals; D015259:Dopamine Agents / Q000494:pharmacology; D015195:Drug Design; D006801:Humans; D011954:Receptors, Dopamine / Q000187:drug effects*
D015259:Dopamine Agents; D011954:Receptors, Dopamine