title: [Neurotoxicity with cytostatic therapy: a review].
abstract: Neurotoxicity is of increasing importance in the treatment of cancer patients. Since the dose-limiting hematological toxicity of most cytostatic drugs can now be overcome by modern supportive therapy, high-dose chemotherapy with curative intent can be used more often. Non-hematological toxicities such as neurotoxicity will therefore become dose-limiting with greater frequency, and to avoid disabling neurological side effects of chemotherapy the drug-induced neurological disturbances must be recognized before irreversible damage has occurred. The neurological side effects of the cytostatic drugs are reviewed.
authors.affiliation: Institut für Medizinische Onkologie, Universität Bern, Inselspital.
authors.forename: T
authors.initials: T
authors.lastname: Cerny
authors.forename: C
authors.initials: C
authors.lastname: Meier
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D001342:Autonomic Nervous System Diseases / Q000139:chemically induced; D002493:Central Nervous System Diseases / Q000139:chemically induced; D006801:Humans; D009422:Nervous System Diseases / Q000139:chemically induced*; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced; D013118:Spinal Cord Diseases / Q000139:chemically induced
chemical_list: D000970:Antineoplastic Agents
vernacular_title: Neurotoxizität bei Zytostatikatherapie: eine Ubersicht.