[Painful legs and moving toes. Neuropathy caused by cytarabine].
A new case of painful legs and moving toes syndrome is reported in a patient with a neuropathy due to high-doses of cytosine arabinoside (Ara C). A few cases of this complication have been reported. The neuropathy was sensory, axonal, and incompletely regressive. Carbamazepine had a dramatic effect on pain and involuntary movements.
Malapert
D
D
Département de Neurosciences, CHU Henri Mondor, Créteil.
Degos
J D
JD
D000293:Adolescent; D001369:Axons; D002220:Carbamazepine / Q000627:therapeutic use; D003561:Cytarabine / Q000008:administration & dosage / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007866:Leg / Q000294:innervation*; D008297:Male; D009069:Movement Disorders / Q000188:drug therapy / Q000209:etiology*; D010146:Pain / Q000188:drug therapy / Q000209:etiology; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy*; D012021:Reflex, Abnormal; D011984:Sensory Receptor Cells; D013577:Syndrome; D014034:Toes / Q000293:injuries* / Q000503:physiopathology
D003561:Cytarabine; D002220:Carbamazepine
Jambes douloureuses et orteils instables. Neuropathie induite par la cytarabine.