Hepatocellular carcinoma: some aspects to improve long-term survival.
Sixty-six patients surviving over 5 years after resection of hepatocellular carcinoma (HCC) are investigated. Of them, subclinical stage amounted to 56.1% (37/66) and moderate stage to 43.9% (29/66). There were 35 cases with small HCC (less than or equal to 5 cm). Cirrhosis was present in 81.1% (54/66). Radical resection was performed in 98.5% (65/66) and palliative resection in 1.5% (1/66). Reoperation for subclinical recurrence and solitary pulmonary metastasis was done in 14 patients, and sequential resection of huge tumors, in three patients. By the end of June 1988, follow-up varied from 60 to 319 months (mean, 115 months); 80.3% of the patients (53/66) are still alive and free of disease; 19.7% (13/66) died with disease. The majority of long-term survivors have returned to their original work; some young patients got married after resection of small HCC 10 years ago, and some can even play football again. Some aspects to improve long-term survival are discussed.
Zhou
X D
XD
Liver Cancer Institute, Shanghai Medical University, People's Republic of China.
Tang
Z Y
ZY
Yu
Y Q
YQ
Ma
Z C
ZC
Yang
B H
BH
Lu
J Z
JZ
Lin
Z Y
ZY
D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000401:mortality* / Q000601:surgery; D002681:China; D005260:Female; D005500:Follow-Up Studies; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012086:Reoperation; D013997:Time Factors