[Antigenic structure of the foot-and-mouth virus. V. Protection of naturally susceptible animals from foot-and-mouth disease using a synthetic peptide].
We have synthesized the peptide representing 135-159 VP1 sequence of A22 strain of the foot-and-mouth disease virus (FMDV). The synthetic peptide induced 100% protection of guinea pigs against the disease. Two-fold immunization of cuttle with the peptide and single immunization of sheep induced full protection of the animals against A22 strain of FMDV.
Iarov
A V
AV
Gel'fanov
V M
VM
Grechaninova
L A
LA
Surovoĭ
A Iu
AIu
Vol'pina
O M
OM
Ivanov
V T
VT
Chepurkin
A V
AV
Driagalin
N N
NN
Ivaniushchenkov
V M
VM
D000595:Amino Acid Sequence; D000818:Animals; D000956:Antigens, Viral; D005537:Aphthovirus / Q000276:immunology*; D002417:Cattle; D004198:Disease Susceptibility; D005536:Foot-and-Mouth Disease / Q000517:prevention & control*; D006168:Guinea Pigs; D007114:Immunization; D008969:Molecular Sequence Data; D010455:Peptides / Q000276:immunology*; D012756:Sheep
D000956:Antigens, Viral; D010455:Peptides
Antigennaia struktura virusa iashchura. V. Zashchita prirodonovospriimchivykh zhivotnykh ot zabolevaniia iashchurom s pomoshch'iu sinteticheskogo peptida.