title: Primary extrarenal Wilms' tumor in children.
abstract: We report three additional cases of primary extrarenal Wilms' tumor and review those cases previously documented. Analysis of the location, histopathology, treatment, and survival of these cases supports the following conclusions: Wilms' tumor may occur in an extrarenal location without primary renal involvement and must be included in the differential diagnosis of abdominal, pelvic, and inguinal masses; an extrarenal location supports a more frequent occurrence of ectopic metanephric blastema than was previously recognized or origin of Wilms' tumor from a more primitive mesodermal tissue; and the natural history and prognosis of extrarenal and renal Wilms' tumors appears similar.
authors.affiliation: Department of Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond.
authors.forename: B H
authors.initials: BH
authors.lastname: Broecker
authors.forename: A A
authors.initials: AA
authors.lastname: Caldamone
authors.forename: N B
authors.initials: NB
authors.lastname: McWilliams
authors.forename: H
authors.initials: H
authors.lastname: Maurer
authors.forename: A
authors.initials: A
authors.lastname: Salzberg
mesh_terms: D000008:Abdominal Neoplasms / Q000473:pathology; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002828:Choristoma / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D009396:Wilms Tumor / Q000473:pathology* / Q000601:surgery