[Lactic acidosis in diabetic patients associated with buformin].
We report two diabetic patients who developed lactic acidosis following the use of Buformin. Treatment consisted of mechanical ventilation, massive bicarbonate administration, circulatory support with dopamine and peritoneal dialysis. Despite this, both patients died.
Huidobro
F
F
Videla
C
C
Hernández
G
G
Torres
H
H
Jimenez
R
R
Pérez
H
H
Díaz
R A
RA
D000140:Acidosis, Lactic / Q000139:chemically induced* / Q000628:therapy; D000368:Aged; D001639:Bicarbonates / Q000627:therapeutic use; D001645:Biguanides / Q000009:adverse effects*; D002026:Buformin / Q000009:adverse effects*; D003920:Diabetes Mellitus / Q000503:physiopathology*; D003925:Diabetic Angiopathies / Q000188:drug therapy; D004298:Dopamine / Q000627:therapeutic use; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D008297:Male; D010530:Peritoneal Dialysis; D012121:Respiration, Artificial; D012964:Sodium / Q000627:therapeutic use; D017693:Sodium Bicarbonate
D001639:Bicarbonates; D001645:Biguanides; D017693:Sodium Bicarbonate; D012964:Sodium; D004298:Dopamine; D002026:Buformin
Acidosis láctica en diabéticos asociada a buformina.