title: [Insulin regulation of 2 kinetically different types of calcium current].
abstract: At least two kinetically different kinds of calcium current are shown to exist in the frog atrial cells. The current with faster activation kinetics is usually depressed by insulin. Insulin also increases the amplitude of the slower calcium current. Pretreatment of atrial cells with cycloheximide does not change the effect of insulin on the fast calcium current but dramatically facilitates the insulin-induced activation of the slower calcium current.
authors.forename: O V
authors.initials: OV
authors.lastname: Nakipova
authors.forename: A V
authors.initials: AV
authors.lastname: Lazarev
authors.forename: T Sh
authors.initials: TSh
authors.lastname: Kshutashvili
authors.forename: V A
authors.initials: VA
authors.lastname: Krupenin
authors.forename: A A
authors.initials: AA
authors.lastname: Freĭdin
mesh_terms: D000818:Animals; D001224:Aspartic Acid / Q000494:pharmacology; D016275:Atrial Function; D015220:Calcium Channels / Q000187:drug effects* / Q000502:physiology; D003513:Cycloheximide / Q000494:pharmacology; D004347:Drug Interactions; D006325:Heart Atria / Q000187:drug effects; D066298:In Vitro Techniques; D007328:Insulin / Q000494:pharmacology*; D007545:Isoproterenol / Q000494:pharmacology; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D011895:Rana ridibunda; D013779:Tetrodotoxin / Q000494:pharmacology; D013997:Time Factors; D015032:Zinc / Q000494:pharmacology*
chemical_list: D015220:Calcium Channels; D007328:Insulin; D001224:Aspartic Acid; D013779:Tetrodotoxin; D003513:Cycloheximide; D015032:Zinc; D007545:Isoproterenol
vernacular_title: Reguliatsiia insulinom dvukh kineticheski razlichnykh tipov kal'tsievogo toka.