title: On the use of double-quantum coherence from an AX3 system (protons in lactate) for spectral editing.
abstract: The suppression of water signals in in vivo proton spectra by means of multiple-quantum filtering can be brought about in several ways. This communication exposes the shortcomings of using purely subtractive filtering techniques to observe signals from metabolites that contain proton couplings of the form AX3.
authors.affiliation: Department of Applied Sciences in Medicine, University of Alberta, Edmonton, Canada.
authors.forename: W
authors.initials: W
authors.lastname: Nosel
authors.forename: L A
authors.initials: LA
authors.lastname: Trimble
authors.forename: J F
authors.initials: JF
authors.lastname: Shen
authors.forename: P S
authors.initials: PS
authors.lastname: Allen
mesh_terms: D004578:Electron Spin Resonance Spectroscopy; D005374:Filtration / Q000379:methods*; D006801:Humans; D007773:Lactates / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008954:Models, Biological; D011522:Protons; D013382:Subtraction Technique; D014867:Water / Q000032:analysis
chemical_list: D007773:Lactates; D011522:Protons; D014867:Water