title: [Lactic acidosis in diabetic patients associated with buformin].
abstract: We report two diabetic patients who developed lactic acidosis following the use of Buformin. Treatment consisted of mechanical ventilation, massive bicarbonate administration, circulatory support with dopamine and peritoneal dialysis. Despite this, both patients died.
authors.forename: F
authors.initials: F
authors.lastname: Huidobro
authors.forename: C
authors.initials: C
authors.lastname: Videla
authors.forename: G
authors.initials: G
authors.lastname: Hernández
authors.forename: H
authors.initials: H
authors.lastname: Torres
authors.forename: R
authors.initials: R
authors.lastname: Jimenez
authors.forename: H
authors.initials: H
authors.lastname: Pérez
authors.forename: R A
authors.initials: RA
authors.lastname: Díaz
mesh_terms: D000140:Acidosis, Lactic / Q000139:chemically induced* / Q000628:therapy; D000368:Aged; D001639:Bicarbonates / Q000627:therapeutic use; D001645:Biguanides / Q000009:adverse effects*; D002026:Buformin / Q000009:adverse effects*; D003920:Diabetes Mellitus / Q000503:physiopathology*; D003925:Diabetic Angiopathies / Q000188:drug therapy; D004298:Dopamine / Q000627:therapeutic use; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D008297:Male; D010530:Peritoneal Dialysis; D012121:Respiration, Artificial; D012964:Sodium / Q000627:therapeutic use; D017693:Sodium Bicarbonate
chemical_list: D001639:Bicarbonates; D001645:Biguanides; D017693:Sodium Bicarbonate; D012964:Sodium; D004298:Dopamine; D002026:Buformin
vernacular_title: Acidosis láctica en diabéticos asociada a buformina.