title: Mutations, epimutations, and the developmental programming of the maize Suppressor-mutator transposable element.
abstract: Information about the structure, function and regulation of the maize Suppressor-mutator (Spm) transposable element has emerged from the genetic and molecular characterization of both deletion mutations and an unconventional type of reversible genetic change (epimutation). The element is subject to an epigenetic mechanism that can either stably inactivate it or specify one of a variety of heritable programs of differential element expression in development. The essay explores the relationship between the Spm element's epigenetic developmental programming mechanism and the determinative events central to plant development and differentiation.
authors.forename: N
authors.initials: N
authors.lastname: Fedoroff
authors.forename: P
authors.initials: P
authors.lastname: Masson
authors.forename: J A
authors.initials: JA
authors.lastname: Banks
mesh_terms: D001483:Base Sequence; D004251:DNA Transposable Elements; D008969:Molecular Sequence Data; D009154:Mutation; D010944:Plants / Q000235:genetics*; D013489:Suppression, Genetic; D003313:Zea mays / Q000235:genetics
chemical_list: D004251:DNA Transposable Elements