title: Characterization of 5' truncated transposed copies of the I factor in Drosophila melanogaster.
abstract: I factors in Drosophila melanogaster are transposable elements structurally related to Mammalian LINEs. Their transposition is activated at high frequencies during I-R hybrid dysgenesis and is associated with the production of mutations of various sorts. Very few of these mutations have been studied at the molecular level; those reported so far result either from chromosomal rearrangements or from insertions of complete I factors. We have analysed three I-R induced yellow mutations and have found that one of them is due to the insertion of an I element very similar to the complete I factor, whereas the other two are due to insertions of I elements that are truncated at their 5' ends; one of them exhibits an unusual 3' end. We discuss possible mechanisms of production of such modified I elements.
authors.affiliation: Laboratoire de Génétique, Unité associée au CNRS no. 360, Université Blaise Pascal, Aubiere, France.
authors.forename: I
authors.initials: I
authors.lastname: Busseau
authors.forename: A
authors.initials: A
authors.lastname: Pelisson
authors.forename: A
authors.initials: A
authors.lastname: Bucheton
mesh_terms: D000818:Animals; D002875:Chromosomes / Q000648:ultrastructure; D004251:DNA Transposable Elements; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D008297:Male; D009154:Mutation; D012091:Repetitive Sequences, Nucleic Acid
chemical_list: D004251:DNA Transposable Elements