The cardiac actin locus (Actc-1) is not on mouse chromosome 17 but is linked to beta 2-microglobulin on chromosome 2.
A restriction fragment variant and recombinant inbred strains were used to show that the cardiac actin locus (Actc-1) is closely linked to beta 2-microglobulin (B2m) and several other loci on chromosome 2 of the mouse. Close linkage of Actc-1 and B2m in both man and mouse provides another example of a chromosomal segment that has been conserved since the divergence of the lineages leading to these two species.
Crosby
J L
JL
Jackson Laboratory, Bar Harbor, Maine 04609.
Phillips
S J
SJ
Nadeau
J H
JH
D000483:Alleles; D000818:Animals; D002874:Chromosome Mapping; D002884:Chromosomes, Human, Pair 15; D008040:Genetic Linkage; D006801:Humans; D051379:Mice; D008815:Mice, Inbred Strains; D012150:Polymorphism, Restriction Fragment Length; D013045:Species Specificity; D001613:beta 2-Microglobulin / Q000235:genetics*
D001613:beta 2-Microglobulin