title: Mixed müllerian tumors of the uterus: a clinicopathologic study.
abstract: Forty-seven cases of mixed müllerian tumors of the uterus were analyzed clinically and pathologically. All patients but one were postmenopausal. Vaginal bleeding was the most frequent presenting symptom, followed by abdominal mass and pelvic pain. Long-term survival was found only in those cases in which the tumor was localized to the uterus (surgical stage I), particularly if it arose from a benign endometrial polyp. No correlation could be established between survival and tumor size, depth of myometrial invasion, or histologic type of sarcoma. Tumors arising after previous irradiation had a poor prognosis. Treatment included surgery, radiation, and chemotherapy. The cumulative probability of 5-year survival was 35%.
authors.affiliation: Department of Obstetrics and Gynecology, University of Texas, Galveston.
authors.forename: T V
authors.initials: TV
authors.lastname: Dinh
authors.forename: R E
authors.initials: RE
authors.lastname: Slavin
authors.forename: B S
authors.initials: BS
authors.lastname: Bhagavan
authors.forename: E V
authors.initials: EV
authors.lastname: Hannigan
authors.forename: E M
authors.initials: EM
authors.lastname: Tiamson
authors.forename: R B
authors.initials: RB
authors.lastname: Yandell
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D009367:Neoplasm Staging; D009373:Neoplasms, Germ Cell and Embryonal / Q000401:mortality / Q000473:pathology* / Q000556:secondary / Q000628:therapy; D012509:Sarcoma / Q000473:pathology; D014594:Uterine Neoplasms / Q000401:mortality / Q000473:pathology* / Q000628:therapy