title: [Value of the CRF test in primary and secondary adrenal insufficiency].
abstract: The ACTH and cortisol responses after CRF administration were studied in 21 patients with adrenal failure and compared with those obtained in 15 control subjects. In patients with Addison's disease, cortisol and ACTH responses were respectively abolished or excessive. In patients with secondary adrenal failure, a unique bolus injection of CRF allows the differentiation between pituitary or hypothalamic secretory defect. With regard to previous reports, the usefulness of CRF test in primary and secondary adrenal failure is stressed.
authors.affiliation: Service d'Endocrinologie, Hôpital Saint-André, Bordeaux.
authors.forename: A
authors.initials: A
authors.lastname: Tabarin
authors.forename: B
authors.initials: B
authors.lastname: Corcuff
authors.forename: M
authors.initials: M
authors.lastname: Dauthribes
authors.forename: F
authors.initials: F
authors.lastname: San-Galli
authors.forename: C
authors.initials: C
authors.lastname: Cochet
authors.forename: J
authors.initials: J
authors.lastname: Guerin
authors.forename: P
authors.initials: P
authors.lastname: Roger
mesh_terms: D000224:Addison Disease / Q000097:blood; D000309:Adrenal Insufficiency / Q000097:blood*; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D000368:Aged; D003346:Corticotropin-Releasing Hormone / Q000494:pharmacology*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008875:Middle Aged; D010901:Pituitary Function Tests
chemical_list: D000324:Adrenocorticotropic Hormone; D003346:Corticotropin-Releasing Hormone; D006854:Hydrocortisone
vernacular_title: Intérêt du test au CRF dans l'insuffisance surrénalienne primitive et secondaire.