Comparison of lung virus titers in susceptible and resistant inbred mouse strains against Sendai virus infection.
Susceptibility of inbred mouse strains to Sendai virus (Mol strain) infection was studied. Although some mouse strains showed age differences in susceptibility between 3-to 4-week-old and 7-to 8-week-old mice, such age differences in susceptibility were not observed in susceptible DBA/2N and resistant BALB/cA mice. In 7-to 8-week-old mice, remarkable strain differences were observed in mortality and intensity of the lung lesions, but not in lung virus titers and serum antibody, between resistant BALB/cA and susceptible DBA/2N mice.
Itoh
T
T
Central Institute for Experimental Animals, Kawasaki, Japan.
Saitoh
M
M
Iwai
H
H
D000367:Age Factors; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D004198:Disease Susceptibility; D005260:Female; D007113:Immunity, Innate; D008168:Lung / Q000382:microbiology*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains / Q000235:genetics* / Q000276:immunology; D010222:Parainfluenza Virus 1, Human / Q000254:growth & development*; D018184:Paramyxoviridae Infections / Q000276:immunology / Q000382:microbiology*
D000914:Antibodies, Viral