title: [Hepatotoxicity induced by cyanamide. A review of the anatomicopathological changes apropos a case].
abstract: A case of toxic liver disease induced by cyanamide in a patient in treatment with this drug during 18 months, is presented. We reviewed the different liver cell alterations produced by a long-term treatment with cyanamide, which produces fibrosis and portal inflammation, as well as polished cells with different characteristic features. These alterations forced the establishing of close controls of patients in treatment with this type of anti-alcoholism drug, as well as the reduction of the duration of therapy, this questioning the efficacy of the treatment of chronic alcoholism with this aversive drug.
authors.forename: F J
authors.initials: FJ
authors.lastname: Román Llorente
authors.forename: E
authors.initials: E
authors.lastname: Iglesias García
authors.forename: S
authors.initials: S
authors.lastname: Fojón Polanco
authors.forename: A
authors.initials: A
authors.lastname: Mariño Callejo
authors.forename: G
authors.initials: G
authors.lastname: Pia Iglesias
authors.forename: P
authors.initials: P
authors.lastname: Gordo Fraile
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D001706:Biopsy; D003484:Cyanamide / Q000009:adverse effects*; D006801:Humans; D008099:Liver / Q000187:drug effects* / Q000473:pathology; D008297:Male
chemical_list: D003484:Cyanamide
vernacular_title: Hepatotoxicidad inducida por cianamida. Revisión de las alteraciones anatomopatológicas a propósito de un caso.