An exaggerated response to beta-adrenergics.
Beta-adrenergics are used frequently in the management of asthma. Tremor has been found to be a limiting side effect with the oral or the inhaled forms. We describe one child who developed gross tremors necessitating an extensive neurologic evaluation to eliminate any other cause. With the results of a normal work-up and the reappearance of tremor when challenged again, the diagnosis of increased sensitivity to the tremorogenic effect of beta-adrenergics was made.
Ozog
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Department of Pediatrics, Children's Memorial Hospital, Chicago, Illinois.
Lerner
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C
D000318:Adrenergic beta-Agonists / Q000009:adverse effects* / Q000627:therapeutic use; D000420:Albuterol / Q000009:adverse effects; D002648:Child; D006801:Humans; D007528:Isoetharine / Q000009:adverse effects; D008297:Male; D009921:Metaproterenol / Q000009:adverse effects; D009460:Neurologic Examination; D013224:Status Asthmaticus / Q000188:drug therapy; D014202:Tremor / Q000139:chemically induced* / Q000503:physiopathology
D000318:Adrenergic beta-Agonists; D009921:Metaproterenol; D000420:Albuterol; D007528:Isoetharine