title: Transformation of myelodysplasia to acute myeloid leukaemia during psoralen photochemotherapy (PUVA) treatment of psoriasis.
abstract: A patient with stable chronic myelomonocytic leukaemia was treated with 8-methoxypsoralen photochemotherapy (PUVA) for erythrodermic psoriasis. After 4 months, transformation to acute myeloid leukaemia (AML) occurred. We would suggest caution when considering PUVA therapy in patients with pre-leukaemic disorders.
authors.affiliation: Department of Dermatology, General Infirmary, Leeds, England.
authors.forename: R A
authors.initials: RA
authors.lastname: Sheehan-Dare
authors.forename: J A
authors.initials: JA
authors.lastname: Cotterill
authors.forename: D L
authors.initials: DL
authors.lastname: Barnard
mesh_terms: D000368:Aged; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis / Q000209:etiology*; D015477:Leukemia, Myelomonocytic, Chronic / Q000150:complications*; D008297:Male; D011701:PUVA Therapy / Q000009:adverse effects*; D011565:Psoriasis / Q000188:drug therapy*