Plant metabolites. Structure and in vitro antiviral activity of quinovic acid glycosides from Uncaria tomentosa and Guettarda platypoda.
A reinvestigation of the bark of Uncaria tomentosa afforded, in addition to the major quinovic acid glycosides 1-3, three further glycosides 4-6. The structures were elucidated by spectral and chemical studies. Furthermore, a series of antiviral tests were performed on all these glycosides and on the related glycosides 7-9, previously isolated from Guettarda platypoda.
Aquino
R
R
Dipartimento di Chimica delle Sostanze Naturali, Universitá di Napoli, Italy.
De Simone
F
F
Pizza
C
C
Conti
C
C
Stein
M L
ML
D000998:Antiviral Agents / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D055598:Chemical Phenomena; D002621:Chemistry; D002849:Chromatography, Gas; D006027:Glycosides / Q000302:isolation & purification / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D010568:Peru; D010946:Plants, Medicinal / Q000032:analysis*; D012328:RNA Viruses / Q000187:drug effects; D012229:Rhinovirus / Q000187:drug effects; D014315:Triterpenes / Q000302:isolation & purification / Q000494:pharmacology*; D014721:Vesicular stomatitis Indiana virus / Q000187:drug effects
D000998:Antiviral Agents; D006027:Glycosides; D014315:Triterpenes