[The protector effect of ribosomal preparations against experimental influenza infection in mice].
A study was conducted on the protective effect of some ribosomal preparations, isolated from chorionic-allantoic membranes of chicken embryos, infected or not with parainfluenza (Sendai) or influenza (AoPR8) virus, in mice experimentally inoculated with influenza virus strain AoPR8 adapted to the mouse. Results showed that the tested preparation, containing ribosomes and polysomes isolated from chorio-allantoic membranes of Sendai virus inoculated chicken embryos, ensure the mice complete protection against AoPR8 virus, if administrated before the control infection.
Popa
L M
LM
Institut de Virologie Stefan S. Nicolau, Bucarest, Roumanie.
Repanovici
R
R
Iliescu
R
R
D000482:Allantois / Q000276:immunology; D000818:Animals; D001685:Biological Factors / Q000302:isolation & purification / Q000627:therapeutic use*; D002458:Cell Fractionation; D002642:Chick Embryo; D002823:Chorion / Q000276:immunology; D004353:Drug Evaluation, Preclinical; D007114:Immunization / Q000379:methods; D051379:Mice; D009976:Orthomyxoviridae Infections / Q000517:prevention & control*; D010222:Parainfluenza Virus 1, Human / Q000276:immunology; D011132:Polyribosomes / Q000276:immunology; D012270:Ribosomes / Q000276:immunology*
D001685:Biological Factors
Effet protecteur de quelques préparations ribosomales contre l'infection expérimentale à virus de la grippe chez la souris.