title: A preliminary report of the short-term effect of carbonated beverage consumption on calcium metabolism in normal women.
abstract: A variety of nutritional factors influence the bioavailability of calcium and increase a woman's risk of osteoporosis. Eight healthy women completed an 8-week metabolic study designed to investigate the effect of nonalcoholic carbonated beverage consumption on calcium metabolism. Compared with women receiving a control diet, women consuming a diet high in nonalcoholic carbonated beverages demonstrated similar mean serum levels of calcium, ionized calcium, phosphorus, alkaline phosphatase, parathyroid hormone, 1,25-dihydroxyvitamin D3, and osteocalcin. Twenty-four-hour urine volume, creatinine clearance, calcium-creatinine ratio, and phosphorus-creatinine ratio were similar during consumption of the diet high in nonalcoholic carbonated beverages and the control diet. Twenty-four-hour cyclic adenosine monophosphate-creatinine ratio was significantly lower in women consuming the diet high in nonalcoholic carbonated beverage compared with women receiving the control diet (342 +/- 27.4 nmol/mmol vs 409 +/- 22.1 nmol/mmol). Consumption of a diet high in nonalcoholic carbonated beverages on a short-term basis does not appear to affect adversely the serum or urinary markers of calcium metabolism.
authors.affiliation: Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, Mass.
authors.forename: S
authors.initials: S
authors.lastname: Smith
authors.forename: J
authors.initials: J
authors.lastname: Swain
authors.forename: E M
authors.initials: EM
authors.lastname: Brown
authors.forename: G
authors.initials: G
authors.lastname: Wyshak
authors.forename: T
authors.initials: T
authors.lastname: Albright
authors.forename: V A
authors.initials: VA
authors.lastname: Ravnikar
authors.forename: I
authors.initials: I
authors.lastname: Schiff
mesh_terms: D000328:Adult; D001628:Beverages; D002118:Calcium / Q000097:blood / Q000378:metabolism* / Q000652:urine; D002253:Carbonated Beverages / Q000009:adverse effects*; D000242:Cyclic AMP / Q000652:urine; D005260:Female; D006801:Humans; D010281:Parathyroid Hormone / Q000097:blood
chemical_list: D010281:Parathyroid Hormone; D000242:Cyclic AMP; D002118:Calcium