Model membrane partition ESR study in the presence of alpha-tocopherol by a new spin probe.
The effect of alpha-tocopherol (alpha T) on partitioning and fluidity changes occurring in phospholipid liposomes have been investigated by monitoring the X-band ESR spectrum of the high resolution amphiphilic spin probe perdeutero-di-t-butyl nitroxide (PDDTBN), which partitions in the lipid and water phase of liposomes, showing all the three resonances from each phase well resolved.
Severcan
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Gruppo di Biofisica Molecolare, Dipartimento di Fisica dell'Università, Perugia, Italy.
Cannistraro
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D015060:1,2-Dipalmitoylphosphatidylcholine / Q000032:analysis; D002073:Butanes; D003903:Deuterium; D004578:Electron Spin Resonance Spectroscopy; D008081:Liposomes / Q000032:analysis; D008560:Membrane Fluidity / Q000187:drug effects*; D009589:Nitrogen Oxides; D013113:Spin Labels; D013816:Thermodynamics; D014810:Vitamin E / Q000494:pharmacology*
D002073:Butanes; D008081:Liposomes; D009589:Nitrogen Oxides; D013113:Spin Labels; D014810:Vitamin E; C007539:di-t-butyl nitroxide; D015060:1,2-Dipalmitoylphosphatidylcholine; D003903:Deuterium