title: Investigation of "mysterious" disease in livestock: hydrocyanic acid poisoning.
abstract: An investigation of "mysterious" disease due to hydrocyanic acid (HCN) poisoning in livestock in this state was carried out. Detailed clinicopathological and pathological studies were conducted. Characteristic signs of acute tympany followed with profuse frothing, convulsions and dyspnea were recorded. Cynosis of the mucosa with characteristic anoxemic tissue changes and a high concentration of HCN in rumen content, feed and skeletal muscles were recorded. These were sufficient to establish the diagnosis. Successful treatment with a specific antidote was achieved, and further morbidity and mortality was checked.
authors.affiliation: Disease Investigation Laboratory, IVRI, Regional Station, Palampur, India.
authors.forename: L
authors.initials: L
authors.lastname: Krishna
authors.forename: R C
authors.initials: RC
authors.lastname: Katoch
mesh_terms: D000818:Animals; D000931:Antidotes / Q000627:therapeutic use; D002417:Cattle; D002418:Cattle Diseases / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D004359:Drug Therapy, Combination; D006856:Hydrogen Cyanide / Q000506:poisoning*; D007194:India; D012977:Sodium Nitrite / Q000627:therapeutic use; D013885:Thiosulfates / Q000627:therapeutic use
chemical_list: D000931:Antidotes; D013885:Thiosulfates; D006856:Hydrogen Cyanide; C017717:sodium thiosulfate; D012977:Sodium Nitrite