title: Serological response to P-fimbriae of Escherichia coli in patients with urinary tract infections.
abstract: The antibody response to P-fimbriae of Escherichia coli in patients with upper urinary tract infections was investigated. In the sera of patients with pyelonephritis obtained at the initial visit to hospital (3 to 7 days after the onset of symptoms), a high incidence of antibodies to P-fimbriae was detected (12 out of 14 patients). P-fimbriated Escherichia coli strains were isolated from urine samples in all of these antibody-positive patients. Antibodies detected by ELISA using purified antigen were essentially IgG and specifically recognized P-fimbriae. These antibodies inhibited completely, or in some cases partially, mannose-resistant hemagglutination with P-fimbriated Escherichia coli.
authors.affiliation: Department of Bacteriology, Nagoya University School of Medicine, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Agata
authors.forename: M
authors.initials: M
authors.lastname: Ohta
authors.forename: H
authors.initials: H
authors.lastname: Miyazawa
authors.forename: M
authors.initials: M
authors.lastname: Mori
authors.forename: N
authors.initials: N
authors.lastname: Kido
authors.forename: N
authors.initials: N
authors.lastname: Kato
mesh_terms: D000907:Antibodies, Bacterial / Q000032:analysis*; D003556:Cystitis / Q000276:immunology; D004926:Escherichia coli / Q000276:immunology*; D005260:Female; D010861:Fimbriae, Bacterial / Q000276:immunology*; D006801:Humans; D011704:Pyelonephritis / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial