The efficacy of benorylate in postoperative dental pain.
The efficacy of a single pre-operative dose of benorylate (4 g) was determined in a double-blind, randomized, placebo-controlled parallel study in patients undergoing removal of a single impacted lower third molar. Patients treated with benorylate 4 g reported significantly less pain between 3-6 h after dosage than those treated with placebo. Overall pain scores at 6 h were significantly less in the benorylate group than the placebo group. However, overall pain scores at 12 h did not differ significantly between treatment groups. It is concluded from this study that a single dose of benorylate 4 g given immediately prior to the removal of an impacted lower third molar provides limited pain control during the postoperative period.
Moore
U
U
Department of Oral Surgery, Dental School, Newcastle upon Tyne, UK.
Seymour
R A
RA
Williams
F M
FM
Nicholson
E
E
Rawlins
M D
MD
D000082:Acetaminophen / Q000627:therapeutic use; D000293:Adolescent; D000328:Adult; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008964:Molar, Third / Q000601:surgery*; D010149:Postoperative Pain / Q000188:drug therapy*; D011897:Random Allocation; D012459:Salicylates / Q000627:therapeutic use*; D014081:Tooth Extraction; D014095:Tooth, Impacted / Q000601:surgery*
D012459:Salicylates; D000082:Acetaminophen