[The action of fenigidin (nifedipine) on central hemodynamics and cerebral blood flow in hypertension].
Nifedipine is an effective agent in hypertensive emergencies as well as in the long-term management of hypertension especially for the patients with an increased risk of cerebral hypoperfusion. Nifedipine exerts its blood lowering effect by reducing total peripheral resistance including cerebrovascular resistance. Despite the marked reduction of perfusion pressure, the cerebral blood flow is maintained by nifedipine.
Ivleva
A Ia
AIa
Udotova
S A
SA
Lepakhin
V K
VK
Tomashevskiĭ
I O
IO
D000368:Aged; D002560:Cerebrovascular Circulation / Q000187:drug effects* / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D008875:Middle Aged; D009543:Nifedipine / Q000494:pharmacology* / Q000627:therapeutic use; D011877:Radionuclide Imaging; D013670:Sodium Pertechnetate Tc 99m; D013997:Time Factors
D013670:Sodium Pertechnetate Tc 99m; D009543:Nifedipine
Deĭstvie fenigidina (nifedipina) na tsentral'nuiu gemodinamiku i mozgovoĭ krovotok pri gipertonii.