title: Herpes simplex virus.
abstract: Genital herpes simplex infection remains an infectious disease having widespread consequences for both adult and neonatal populations. Physicians must understand that the psychologic impact of genital HSV infections frequently is more disabling than the physical manifestations. Sensitivity, compassion, and support are necessary from members of the medical community, and psychologic counseling may help patients cope with HSV and all its implications. Similarly, physicians must downplay the hysteria that has been associated with herpesvirus infections, emerging as a result of intense media coverage in the 1970s and 1980s. Minimizing the number of cases of neonatal herpes through identification of infected women during parturition continues to be important. Recent guidelines suggest a rationale for the management of women at risk for genital HSV. Nevertheless, until newer immunologic and serologic techniques become clinically reliable and allow a correct and rapid diagnosis of herpes simplex infection, identification of the infected woman in labor must be made using detailed clinical history, physical examination, and viral culture.
authors.affiliation: Department of Obstetrics and Gynecology, George Washington University Medical Center, Washington, DC.
authors.forename: H J
authors.initials: HJ
authors.lastname: Landy
authors.forename: J H
authors.initials: JH
authors.lastname: Grossman
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D004261:DNA Replication; D005260:Female; D006558:Herpes Genitalis / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology* / Q000628:therapy; D006561:Herpes Simplex / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology* / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D012008:Recurrence; D018139:Simplexvirus / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology*; D014779:Virus Replication
chemical_list: D000212:Acyclovir