title: Studies of the metabolism of human breast cancer spheroids by NMR.
abstract: Spheroids present a model for tumor behavior in vivo. In NMR studies, a problem of spheroid adhesion occurs. Here, we present a method which overcomes this problem and show the variations in phosphate metabolite concentrations as well as the rate of glucose metabolism as a function of spheroid age.
authors.affiliation: Isotope Department, Weizmann Institute of Science, Rehovot, Israel.
authors.forename: S
authors.initials: S
authors.lastname: Ronen
authors.forename: H
authors.initials: H
authors.lastname: Degani
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D001943:Breast Neoplasms / Q000378:metabolism*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000378:metabolism*; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D010710:Phosphates / Q000378:metabolism; D014407:Tumor Cells, Cultured
chemical_list: D010710:Phosphates; D000255:Adenosine Triphosphate