title: The interaction of temelastine with cytochrome P450 mixed-function oxidase enzymes in vivo and in vitro.
authors.affiliation: Smith Kline & French Research Limited, The Frythe, Welwyn Garden City, Herts, U.K.
authors.forename: R J
authors.initials: RJ
authors.lastname: Chenery
authors.forename: P J
authors.initials: PJ
authors.lastname: Cox
authors.forename: L C
authors.initials: LC
authors.lastname: Rath
authors.forename: P
authors.initials: P
authors.lastname: Standring
authors.forename: H G
authors.initials: HG
authors.lastname: Oldham
mesh_terms: D000818:Animals; D000983:Antipyrine / Q000493:pharmacokinetics; D065607:Cytochrome P-450 Enzyme Inhibitors; D005260:Female; D006207:Half-Life; D006634:Histamine H1 Antagonists / Q000494:pharmacology*; D007700:Kinetics; D008297:Male; D011744:Pyrimidinones / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D065607:Cytochrome P-450 Enzyme Inhibitors; D006634:Histamine H1 Antagonists; D011744:Pyrimidinones; C049054:temelastine; D000983:Antipyrine