title: Polymerase chain reaction for detection of dissemination in gastric lymphoma.
abstract: The polymerase chain reaction (PCR) was used to detect malignant lymphoma cells with the bcl-2 gene rearrangement in the peritoneal washings and bone marrow of a patient with an apparently localised gastric lymphoma. After four courses of cytotoxic drug treatment the cells could no longer be detected in either site. PCR is a useful addition to the staging investigations of non-Hodgkin lymphoma and can also be used to monitor response to treatment.
authors.affiliation: Ludwig Institute for Cancer Research, St Mary's Hospital Medical School, London.
authors.forename: D
authors.initials: D
authors.lastname: Cunningham
authors.forename: T
authors.initials: T
authors.lastname: Hickish
authors.forename: R D
authors.initials: RD
authors.lastname: Rosin
authors.forename: P
authors.initials: P
authors.lastname: Sauven
authors.forename: J H
authors.initials: JH
authors.lastname: Baron
authors.forename: P J
authors.initials: PJ
authors.lastname: Farrell
authors.forename: P
authors.initials: P
authors.lastname: Isaacson
mesh_terms: D001402:B-Lymphocytes; D001856:Bone Marrow Examination; D002874:Chromosome Mapping; D004273:DNA, Neoplasm / Q000032:analysis; D004259:DNA-Directed DNA Polymerase; D004341:Drug Evaluation; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000235:genetics / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D015345:Oligonucleotide Probes; D010533:Peritoneal Lavage; D011518:Proto-Oncogene Proteins / Q000032:analysis; D013274:Stomach Neoplasms / Q000235:genetics / Q000473:pathology*; D014178:Translocation, Genetic
chemical_list: D004273:DNA, Neoplasm; D015345:Oligonucleotide Probes; D011518:Proto-Oncogene Proteins; D004259:DNA-Directed DNA Polymerase