title: R68070, a combined thromboxane/endoperoxide receptor antagonist (TRA) and thromboxane synthase inhibitor (TSI), prolongs the bleeding time more than aspirin in man.
authors.affiliation: Center for Thrombosis and Vascular Research, K.U.Leuven, Belgium.
authors.forename: B
authors.initials: B
authors.lastname: Hoet
authors.forename: J
authors.initials: J
authors.lastname: Arnout
authors.forename: J
authors.initials: J
authors.lastname: Vermylen
mesh_terms: D001241:Aspirin / Q000494:pharmacology; D001760:Bleeding Time; D001792:Blood Platelets / Q000187:drug effects* / Q000502:physiology; D002986:Clinical Trials as Topic; D000242:Cyclic AMP / Q000097:blood; D004311:Double-Blind Method; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D010421:Pentanoic Acids / Q000494:pharmacology*; D011453:Prostaglandins / Q000097:blood; D011725:Pyridines / Q000494:pharmacology*; D011897:Random Allocation; D011982:Receptors, Prostaglandin; D017482:Receptors, Thromboxane; D013930:Thromboxane-A Synthase / Q000037:antagonists & inhibitors*; D014631:Valerates / Q000494:pharmacology*
chemical_list: D010421:Pentanoic Acids; D011453:Prostaglandins; D011725:Pyridines; D011982:Receptors, Prostaglandin; D017482:Receptors, Thromboxane; D014631:Valerates; D000242:Cyclic AMP; D013930:Thromboxane-A Synthase; C060219:ridogrel; D001241:Aspirin