title: Investigations into the toxicity of Echium plantagineum in sheep. 1. Field grazing experiments.
abstract: A field grazing trial was undertaken to monitor the health and production of crossbred sheep grazing pasture where Echium plantagineum constituted a considerable proportion of the available forage. The trial, conducted for 19 months over successive grazing seasons, demonstrated a significant difference in production, with sheep on the E. plantagineum pasture being lighter and growing less wool compared with sheep on Echium-free pasture. No mortalities involving pyrrolizidine alkaloid poisoning were recorded in sheep grazing E. plantagineum, although there was histological evidence of moderately severe liver damage associated with high liver copper concentrations in at least one sheep following the grazing of large quantities of the plant.
authors.affiliation: New South Wales Department of Agriculture and Fisheries, Agricultural Research and Veterinary Centre, Orange.
authors.forename: J T
authors.initials: JT
authors.lastname: Seaman
authors.forename: W S
authors.initials: WS
authors.lastname: Turvey
authors.forename: S J
authors.initials: SJ
authors.lastname: Ottaway
authors.forename: R J
authors.initials: RJ
authors.lastname: Dixon
authors.forename: A R
authors.initials: AR
authors.lastname: Gilmour
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001706:Biopsy; D001835:Body Weight; D003300:Copper / Q000378:metabolism / Q000506:poisoning; D005260:Female; D008107:Liver Diseases / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D009753:Nutritive Value; D010939:Plant Poisoning / Q000473:pathology / Q000662:veterinary*; D010947:Plants, Toxic / Q000378:metabolism; D011763:Pyrrolizidine Alkaloids / Q000378:metabolism / Q000506:poisoning*; D012621:Seasons; D012756:Sheep; D012757:Sheep Diseases / Q000209:etiology* / Q000473:pathology; D014935:Wool; D005723:gamma-Glutamyltransferase / Q000097:blood
chemical_list: D011763:Pyrrolizidine Alkaloids; D003300:Copper; D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases