title: Solute adsorption and concentration-dependent permeability in certain polymer films.
abstract: Certain parameters (solute adsorption, permeability and swellability) of films of a cationic acrylatemethacrylate copolymer have been determined as functions of the solute (sulphacetamide sodium) concentrations. Both permeability coefficients and the free (unadsorbed fraction of solute increased almost proportionately during increase in solute concentration 1-5%, above 5%, further increase in the fraction of free solute was slight, while the permeability coefficients decreased slightly. The solute also reduced film swellability but the observed concentration-dependent permeability related more to the adsorption phenomenon.
authors.affiliation: Department of Pharmaceutics, University of Benin, Benin City, Nigeria.
authors.forename: R S
authors.initials: RS
authors.lastname: Okor
mesh_terms: D000327:Adsorption; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D008567:Membranes, Artificial; D008970:Molecular Weight; D010539:Permeability; D011108:Polymers; D011109:Polymethacrylic Acids
chemical_list: D008567:Membranes, Artificial; D011108:Polymers; D011109:Polymethacrylic Acids