[Carcinogenicity of zeolite-phillipsite].
Phillipsite dust was intrapleurally administered to random-bred rats by 20 mg in 0.5 ml of saline three times with an interval of a month. Higher incidence of hemoblastoses has been experimentally found in exposed animals compared to the control ones. One rat developed pleural mesothelioma, two rats lung adenocarcinoma. It was concluded that phillipsite has weak carcinogenic activity.
Pylev
L N
LN
Kulagina
T F
TF
Grankina
E P
EP
Chelishchev
N F
NF
Berenshteĭn
B G
BG
D000230:Adenocarcinoma / Q000209:etiology*; D000538:Aluminum Silicates / Q000009:adverse effects*; D000818:Animals; D015197:Carcinogenicity Tests; D002273:Carcinogens; D005260:Female; D008175:Lung Neoplasms / Q000209:etiology*; D008297:Male; D008325:Mammary Neoplasms, Experimental / Q000209:etiology*; D008654:Mesothelioma / Q000209:etiology*; D010997:Pleural Neoplasms / Q000209:etiology*; D051381:Rats; D017641:Zeolites
D000538:Aluminum Silicates; D002273:Carcinogens; C061947:phillipsite; D017641:Zeolites
Kantserogennos't tsiolita-fillipsita.