[Subtotal adrenalectomy versus autotransplantation of the adrenal cortex--an alternative procedure in bilateral adrenalectomy in MEN II?].
Complete loss of steroid production is a very remarkable effect of total adrenalectomy. This is the reason why attempt was made to preserve some adrenal cortex function in cases with bilateral adrenalectomy. Till now successful autografting of adrenal cortex has been reported only in cases with Cushing's syndrome. We now report on two cases with MEN II syndrome, in whom autografting into the rectus muscle was done successfully. In order to compare results, data on two patients with subtotal adrenalectomy are given. Outcome was similar. In all 4 cases function of adrenal cortex was demonstrated by scintigraphy and by blood chemistry. In one case with autotransplantation and in another with subtotal resection, the remaining adrenal tissue showed response to ACTH. Provided more experience, in our opinion subtotal adrenalectomy and adrenal autotransplantation in cases of MEN II syndrome might turn out to prove as equivalent procedures.
Klempa
I
I
Allgemein-Chirurgische Klinik, Bremen.
Menzel
J
J
Baca
I
I
D000009:Abdominal Muscles / Q000601:surgery; D000302:Adrenal Cortex / Q000637:transplantation*; D000310:Adrenal Gland Neoplasms / Q000235:genetics / Q000601:surgery*; D000315:Adrenalectomy / Q000379:methods*; D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009377:Multiple Endocrine Neoplasia / Q000235:genetics / Q000601:surgery*; D010673:Pheochromocytoma / Q000235:genetics / Q000601:surgery*; D013536:Suture Techniques
Subtotale Adrenalektomie versus Autotransplantation der Nebennierenrinde--Alternativverfahren bei der bilateralen Adrenalektomie bei MEN II?