title: [Effect of renovascular roentgen contrast media on the function of the healthy kidney--an individual comparison].
abstract: In 50 patients with healthy kidneys the excretion of tubular enzymes was determined quantitatively before and after administration of an ionic and a non-ionic contrast medium and compared intra-individually. Both preparations produced a highly significant increase in enzyme levels to about twice the initial value, the increase being significantly lower with the non-ionic contrast medium. This effect was fully reversible within 24 hours. No noticeable change was seen within the examination period of 48 hours in respect of creatinine and creatinine clearance levels.
authors.affiliation: Institut für klinische Strahlenkunde, Johannes Gutenberg-Universität, Mainz.
authors.forename: S
authors.initials: S
authors.lastname: Zapf
authors.forename: J E
authors.initials: JE
authors.lastname: Scherberich
mesh_terms: D000410:Alanine Transaminase / Q000652:urine; D000469:Alkaline Phosphatase / Q000652:urine; D003287:Contrast Media; D003404:Creatinine / Q000097:blood; D005260:Female; D005919:Glomerular Filtration Rate / Q000187:drug effects; D006801:Humans; D007479:Iopamidol / Q000633:toxicity*; D007483:Iothalamic Acid / Q000633:toxicity / Q000031:analogs & derivatives; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D016032:Randomized Controlled Trials as Topic; D005723:gamma-Glutamyltransferase / Q000652:urine
chemical_list: D003287:Contrast Media; D007483:Iothalamic Acid; C016525:ioglicic acid; D003404:Creatinine; D005723:gamma-Glutamyltransferase; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D007479:Iopamidol
vernacular_title: Einfluss nierengängiger Rötgenkontrasmittel auf die Funktion der gesunden Niere--ein intraindividueller Vergleich.