Steroid-induced complete remission in a case of primary cerebral non-Hodgkin's lymphoma.
A case of a primary non-Hodgkin's lymphoma of the CNS is reported in which a complete and stable disappearance of an enhancing mass lesion on the CT scan after treatment with dexamethasone was followed by the occurrence of a high-grade malignant lymphoma in the opposite hemisphere 18 months later. The long-lasting and stable remission suggests a direct oncolytic effect of corticosteroids on lymphoma cells. Furthermore, this case illustrates the usefulness of repeated CT examinations in patients with CNS lymphoma and steroid treatment.
Pohl
P
P
Department of Neurology, University of Innsbruck, Austria.
Oberhuber
G
G
Dietze
O
O
Vogl
G
G
Pallua
A K
AK
Plangger
C A
CA
Huber
H
H
D000368:Aged; D001932:Brain Neoplasms; D003907:Dexamethasone / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis*; D012074:Remission Induction
D003907:Dexamethasone