Presence of catecholaminergic axon-terminals containing beta-adrenergic receptor in the periventricular zone of the rat hypothalamus.
The present study, using a light microscopic double-immunofluorescence method, has revealed the presence of fibers containing both tyrosine hydroxylase- and beta-adrenergic receptor-like immunoreactivities in the rat hypothalamic periventricular zone. Subsequent immunoelectron microscopic analysis demonstrated that these belong to axon terminals. These findings suggest that presynaptic beta-adrenergic receptor is present in catecholaminergic terminals.
Wanaka
A
A
Department of Anatomy II, Osaka University School of Medicine, Japan.
Malbon
C C
CC
Matsumoto
M
M
Kamada
T
T
Tohyama
M
M
D000818:Animals; D002395:Catecholamines / Q000378:metabolism*; D007150:Immunohistochemistry; D008854:Microscopy, Electron; D009411:Nerve Endings / Q000378:metabolism* / Q000648:ultrastructure; D010286:Paraventricular Hypothalamic Nucleus / Q000166:cytology / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D011943:Receptors, Adrenergic, beta / Q000276:immunology / Q000378:metabolism*; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism
D002395:Catecholamines; D011943:Receptors, Adrenergic, beta; D014446:Tyrosine 3-Monooxygenase