Laboratory diagnosis of the first cases of HIV-2 infection in Canada.
Until recently the geographic distribution of infection due to human immunodeficiency virus type 2 (HIV-2) had excluded North America. We report the first two cases of such infection in Canada. Both people came from endemic areas of western Africa and were asymptomatic. The results of a commercial enzyme immunoassay specific for HIV-1 antibody were positive in both cases, but those of the Western blot technique were indeterminate. The Western blot technique specific for HIV-2 antibody and the indirect fluorescent antibody test were used to verify the presence of HIV-2 antibody.
Neumann
P W
PW
Bureau of Laboratories Services, Federal Centre for AIDS, Ottawa, Ont.
O'Shaughnessy
M V
MV
Lepine
D
D
D'Souza
I
I
Major
C
C
McLaughlin
B
B
D000328:Adult; D015153:Blotting, Western; D002170:Canada; D006800:Deltaretrovirus Infections / Q000453:epidemiology / Q000276:immunology* / Q000635:transmission; D003937:Diagnosis, Differential; D005260:Female; D005455:Fluorescent Antibody Technique / Q000295:instrumentation; D015483:HIV Antibodies / Q000032:analysis*; D015497:HIV-1 / Q000276:immunology; D015498:HIV-2 / Q000276:immunology*; D006801:Humans; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000276:immunology*; D011933:Reagent Kits, Diagnostic
D015483:HIV Antibodies; D011933:Reagent Kits, Diagnostic