Nerve growth factor receptor immunoreactivity in the neuronal perikarya of human sensory and sympathetic nerve ganglia.
We examined immunohistochemically the dorsal root ganglia, sympathetic ganglia, spinal cord, ventral and dorsal roots, and sciatic nerves obtained at autopsy from adult humans, using a monoclonal antibody against the human nerve growth factor receptor. We observed labelling in a granular pattern in the neuronal perikarya of dorsal root and sympathetic nerve ganglia. Ventral horn cells and axons were not labelled.
Sobue
G
G
Fourth Department of Internal Medicine, Aichi Medical University, Japan.
Yasuda
T
T
Mitsuma
T
T
Pleasure
D
D
D000911:Antibodies, Monoclonal; D005727:Ganglia, Spinal / Q000032:analysis* / Q000166:cytology; D005728:Ganglia, Sympathetic / Q000032:analysis* / Q000166:cytology; D006801:Humans; D007150:Immunohistochemistry; D009474:Neurons / Q000032:analysis; D011956:Receptors, Cell Surface / Q000032:analysis*; D017475:Receptors, Nerve Growth Factor
D000911:Antibodies, Monoclonal; D011956:Receptors, Cell Surface; D017475:Receptors, Nerve Growth Factor