[Functional properties of isolated kidney mitochondria of rats in food deprivation].
The respiratory properties of isolated rat renal mitochondria after fasting conditions (2-8 days) are estimated in comparison with the parameters of normal feeded control animals. After an extrem starvation time of 8 days the active and uncoupled respiration of glutamate/malate, but not of succinate were reduced, whereas the respiratory control index and the ADP/O-Quotient did remain unchanged. In conclusion, malnutrition do not influence the renal function due to mitochondrial changes.
Jung
K
K
Abteilung für experimentelle Organtransplantation, Bereiches Medizin (Charité) der Humboldt-Universität zu Berlin.
D000244:Adenosine Diphosphate / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D004734:Energy Metabolism; D005971:Glutamates / Q000378:metabolism; D018698:Glutamic Acid; D007668:Kidney / Q000503:physiopathology*; D008293:Malates / Q000378:metabolism; D008297:Male; D008928:Mitochondria / Q000503:physiopathology*; D010101:Oxygen Consumption; D051381:Rats; D011919:Rats, Inbred Strains; D013217:Starvation / Q000503:physiopathology*; D013386:Succinates / Q000378:metabolism; D019802:Succinic Acid
D005971:Glutamates; D008293:Malates; D013386:Succinates; D018698:Glutamic Acid; D000244:Adenosine Diphosphate; C030298:malic acid; D000255:Adenosine Triphosphate; D019802:Succinic Acid
Funktionelle Eigenschaften isolierter Nierenmitochondrien von Ratten unter Nahrungsentzug.