Unknotting the complexities of multidrug resistance: the involvement of DNA topoisomerases in drug action and resistance.
Beck
W T
WT
Department of Biochemical and Clinical Pharmacology, St. Jude Children's Research Hospital, Memphis, TN 38101.
D000255:Adenosine Triphosphate / Q000378:metabolism; D002166:Camptothecin / Q000494:pharmacology; D002455:Cell Division; D002460:Cell Line; D004264:DNA Topoisomerases, Type I / Q000235:genetics* / Q000378:metabolism; D004250:DNA Topoisomerases, Type II / Q000235:genetics* / Q000378:metabolism; D004347:Drug Interactions / Q000235:genetics; D004351:Drug Resistance / Q000235:genetics*; D006801:Humans; D009154:Mutation; D010641:Phenotype; D059004:Topoisomerase I Inhibitors; D059005:Topoisomerase II Inhibitors
D059004:Topoisomerase I Inhibitors; D059005:Topoisomerase II Inhibitors; D000255:Adenosine Triphosphate; D004264:DNA Topoisomerases, Type I; D004250:DNA Topoisomerases, Type II; D002166:Camptothecin