[Biochemical requirements in tocolysis].
By a specific bond of 3H-dihydroalprenolol the number (Bmax) and characteristic (Kd) of sympathetic beta-receptors in cell membranes of the myometrium and lymphocytes of peripheral blood was assessed. The authors examined six tissue specimens taken during planned termination of pregnancy during the 38th-40th week by primary Caesarean section parallel with a peripheral blood sample. In healthy women even at the end of pregnancy the myometrium contains ample amounts of specific beta-receptors. As compared with the myometrium, the lymphocytes of the peripheral blood contain beta-adrenergic receptors of the same type as the myometrium but in much smaller amounts. So far it was not possible to show a correlation between the number of sympathetic beta-receptors in the membranes of the myometrium and of lymphocytes in the peripheral blood.
Kölblová
V
V
Krulík
R
R
Kölbel
F
F
D004082:Dihydroalprenolol / Q000378:metabolism; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000378:metabolism; D009215:Myometrium / Q000378:metabolism*; D011247:Pregnancy; D011943:Receptors, Adrenergic, beta / Q000378:metabolism*; D015145:Tocolysis
D011943:Receptors, Adrenergic, beta; D004082:Dihydroalprenolol
Biochemické predpoklady tokolýzy.