Rickets with alopecia-remission following a course of 1-alpha-hydroxy vitamin D3 therapy.
A child is described with rickets and alopecia who did not respond to high doses of vitamin D3 but who responded to a small dose of 1-alpha-hydroxyvitamin D3. Treatment was continued for 2 years and then stopped. She has not shown any signs of relapse 1 year after stopping treatment. Her alopecia, however, has remained unchanged. One year after stopping treatment, her serum 25-hydroxycholecalciferol and parathormone levels were within normal limits but serum 1,25-dihydroxycholecalciferol was elevated.
Manandhar
D S
DS
Department of Paediatrics, Al Jahra Hospital, Kuwait.
Sarkawi
S
S
Hunt
M C
MC
D000505:Alopecia / Q000150:complications*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006887:Hydroxycholecalciferols / Q000008:administration & dosage / Q000627:therapeutic use*; D007015:Hypophosphatemia, Familial / Q000150:complications / Q000188:drug therapy*; D013577:Syndrome
D006887:Hydroxycholecalciferols; C008088:alfacalcidol