Hepatitis A virus hemagglutination and a test for hemagglutination inhibition antibodies.
Like enteroviruses, hepatitis A virus (HAV) hemagglutinated various species of erythrocytes under similar conditions. HAV-specific antibodies in both acute- and convalescent-phase sera were found to inhibit hemagglutination. The HAV hemagglutination inhibition test can be used for diagnosis, epidemiological surveillance, and vaccine assessment.
Eckels
K H
KH
Department of Biologics Research, Walter Reed Army Institute of Research, Washington, D.C. 20307-5100.
Summers
P L
PL
Dubois
D R
DR
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D000918:Antibody Specificity; D002460:Cell Line; D004797:Enzyme-Linked Immunosorbent Assay; D006385:Hemagglutination Inhibition Tests; D006387:Hemagglutination, Viral; D006506:Hepatitis A / Q000175:diagnosis / Q000276:immunology*; D006507:Hepatovirus / Q000276:immunology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007106:Immune Sera / Q000276:immunology; D013696:Temperature
D000914:Antibodies, Viral; D007106:Immune Sera