A preliminary report of the short-term effect of carbonated beverage consumption on calcium metabolism in normal women.
A variety of nutritional factors influence the bioavailability of calcium and increase a woman's risk of osteoporosis. Eight healthy women completed an 8-week metabolic study designed to investigate the effect of nonalcoholic carbonated beverage consumption on calcium metabolism. Compared with women receiving a control diet, women consuming a diet high in nonalcoholic carbonated beverages demonstrated similar mean serum levels of calcium, ionized calcium, phosphorus, alkaline phosphatase, parathyroid hormone, 1,25-dihydroxyvitamin D3, and osteocalcin. Twenty-four-hour urine volume, creatinine clearance, calcium-creatinine ratio, and phosphorus-creatinine ratio were similar during consumption of the diet high in nonalcoholic carbonated beverages and the control diet. Twenty-four-hour cyclic adenosine monophosphate-creatinine ratio was significantly lower in women consuming the diet high in nonalcoholic carbonated beverage compared with women receiving the control diet (342 +/- 27.4 nmol/mmol vs 409 +/- 22.1 nmol/mmol). Consumption of a diet high in nonalcoholic carbonated beverages on a short-term basis does not appear to affect adversely the serum or urinary markers of calcium metabolism.
Smith
S
S
Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, Mass.
Swain
J
J
Brown
E M
EM
Wyshak
G
G
Albright
T
T
Ravnikar
V A
VA
Schiff
I
I
D000328:Adult; D001628:Beverages; D002118:Calcium / Q000097:blood / Q000378:metabolism* / Q000652:urine; D002253:Carbonated Beverages / Q000009:adverse effects*; D000242:Cyclic AMP / Q000652:urine; D005260:Female; D006801:Humans; D010281:Parathyroid Hormone / Q000097:blood
D010281:Parathyroid Hormone; D000242:Cyclic AMP; D002118:Calcium