Cushing's syndrome due to ACTH-production of an ovarian carcinoid.
The case of a 56-year old woman with severe Cushing's syndrome due to ovarian ACTH-production is described. Both clinical picture and biochemical pattern were consistent with the ectopic ACTH syndrome. ACTH was found by specific immunohistochemical staining in a carcinoid tumor of the patient's right ovary. In contrast, pituitary cells exhibited immunoreactive ACTH to only a minimum extent.
Schlaghecke
R
R
Abteilung Innere Medizin, Universität Düsseldorf.
Kreuzpaintner
G
G
Bürrig
K F
KF
Juli
E
E
Kley
H K
HK
D000182:ACTH Syndrome, Ectopic / Q000097:blood* / Q000473:pathology; D000324:Adrenocorticotropic Hormone / Q000097:blood; D002276:Carcinoid Tumor / Q000097:blood / Q000150:complications* / Q000473:pathology; D003480:Cushing Syndrome / Q000097:blood* / Q000473:pathology; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000097:blood / Q000150:complications* / Q000473:pathology; D010053:Ovary / Q000473:pathology; D009384:Paraneoplastic Endocrine Syndromes / Q000097:blood*
D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone