title: Clinical outcome of coronary angioplasty for single-vessel disease.
abstract: The acute and long-term results of coronary angioplasty in 412 patients with single-vessel coronary artery disease are reported. Angiographic success was observed in 85.5% of all lesions and 84.7% of all arteries in which dilatation was attempted. Success rates improved during the study; since 1985, the angiographic success rate for non-occluded arteries has been 91.0%. Early complications occurred in 6.8%; angioplasty achieved clinical success in 80.3% of all patients at discharge from hospital. The median duration of follow-up was 772 days, with clinical status established for 98.8% of patients. 5 years after clinically successful angioplasty, cumulative cardiac survival was 96.6% and freedom from cardiac death and myocardial infarction was 90.4% (95.8% and 85.4%, respectively, on intention-to-treat analysis). Within 5 years of successful angioplasty, 12.4% of survivors underwent coronary bypass surgery and 16.9% had repeat angioplasty. Freedom from all cardiac events at 5 years was 70.2% after clinically successful angioplasty and 60.2% on intention-to-treat analysis. Angina symptoms were improved in over 80% of patients and abolished in 75%.
authors.affiliation: Department of Cardiology, Guy's Hospital, London.
authors.forename: R A
authors.initials: RA
authors.lastname: Henderson
authors.forename: S
authors.initials: S
authors.lastname: Karani
authors.forename: C A
authors.initials: CA
authors.lastname: Bucknall
authors.forename: A
authors.initials: A
authors.lastname: Dritsas
authors.forename: A D
authors.initials: AD
authors.lastname: Timmis
authors.forename: E
authors.initials: E
authors.lastname: Sowton
mesh_terms: D000203:Activities of Daily Living; D000206:Actuarial Analysis; D000328:Adult; D000368:Aged; D000800:Angioplasty, Balloon / Q000009:adverse effects / Q000379:methods; D003327:Coronary Disease / Q000401:mortality / Q000628:therapy*; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000401:mortality; D011379:Prognosis