Increased iodine-123-iodoamphetamine uptake in hepatomas.
In the current study, two cases of hepatoma are reported in which N-isopropyl-(I-123)-p-iodoamphetamine (IMP) liver scan demonstrated increased accumulation in the tumor corresponding to the areas enhanced on contrast enhanced CT (CE-CT). In contrast, there was no IMP accumulation in the necrotic area of the tumor in which no enhancement was found on CE-CT. Thus, IMP liver scan seems to have the potential to assess the viability of a hepatoma as well as to detect and localize it.
Suto
Y
Y
Department of Radiology, Tottori University, School of Medicine, Japan.
Ishii
Y
Y
Caner
B E
BE
Noguchi
M
M
Katsube
Y
Y
Torizuka
K
K
D000662:Amphetamines; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging* / Q000188:drug therapy; D005500:Follow-Up Studies; D006801:Humans; D007089:Image Enhancement; D007457:Iodine Radioisotopes; D020367:Iofetamine; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging; D015899:Tomography, Emission-Computed, Single-Photon
D000662:Amphetamines; D007457:Iodine Radioisotopes; D020367:Iofetamine