[The effect of alloxan on activity of various enzymes of phosphorus metabolism in vitro].
Effect of alloxan on activity of acetylphosphatase, alkaline and acid phosphatases, phenylpyrophosphatase was studied in vitro. Alloxan at concentrations 100 microM-10 mM inhibited acid phosphatase and especially alkaline phosphatase. Reducing agents (pyrocatechol, hydroquinone, ascorbic acid), which are easily converted into corresponding oxidized forms, at concentrations 100 microM-1.0 mM activated alkaline phosphatase in rat kidney and small intestine.
Parsadanian
G K
GK
Sarkisian
L V
LV
Aslanian
I G
IG
Adunts
G T
GT
Adunts
G G
GG
D000135:Acid Phosphatase / Q000037:antagonists & inhibitors*; D000469:Alkaline Phosphatase / Q000037:antagonists & inhibitors*; D000496:Alloxan / Q000494:pharmacology*; D000818:Animals; D002645:Chickens; D003921:Diabetes Mellitus, Experimental / Q000201:enzymology; D066298:In Vitro Techniques; D010744:Phosphoric Monoester Hydrolases / Q000037:antagonists & inhibitors*; D010758:Phosphorus / Q000378:metabolism*; D010766:Phosphorylation; D051381:Rats; D013552:Swine; D014018:Tissue Distribution
D010758:Phosphorus; D000496:Alloxan; C018735:acetylphosphatase; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D010744:Phosphoric Monoester Hydrolases
Vliianie alloksana in vitro na aktivnost' nekotorykh fermentov fosfornogo obmena.