Post-exposure prophylaxis for hepatitis B: active or passive?
After exposure to hepatitis B (HB) virus, passive immunisation with HB immune globulin is widely used for protection while active immunity is induced by conventional vaccination regimens. Protective antibody titres can be achieved much more quickly with accelerated vaccination, and the role of passive immunisation may need to be reconsidered.
Iwarson
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Department of Infectious Diseases, Ostra Hospital, University of Göteborg, Sweden.
D000328:Adult; D000818:Animals; D004781:Environmental Exposure; D005260:Female; D006509:Hepatitis B / Q000517:prevention & control* / Q000635:transmission; D006801:Humans; D007116:Immunization, Passive / Q000379:methods*; D007231:Infant, Newborn; D002679:Pan troglodytes; D013997:Time Factors; D014611:Vaccination