title: [Stereotaxic biopsy of intracranial processes: validity of histologic diagnosis].
abstract: The diagnostic validity of stereotactic intracranial biopsies was investigated in 70 patients retrospectively. In 56 cases (80%) the presence of a neoplastic lesion as well as its grade of malignancy was proved by cytological, histological and immunohistochemical techniques. An inflammatory or vascular lesion was found in 8 patients (11.4%). In 6 patients (8.6%) the nature of the lesion remained unclear because of nonspecific histological findings. In 27 cases a correlation was found between the biopsy specimens and corresponding material obtained during open surgery or autopsy. 24 concordant results were found (88.9%). In one case a malignant tumour was classified only according to the findings obtained at operation. In two cases subsequently diagnosed as glioblastoma biopsy reported a higher differentiated astrocytoma and a non-neoplastic lesion, respectively. These results confirm stereotactic biopsy of intracranial lesions as a method with low complication rate and high diagnostic validity.
authors.affiliation: Neurochirurgische Universitätsklinik, Wien.
authors.forename: K
authors.initials: K
authors.lastname: Ungersböck
authors.forename: M
authors.initials: M
authors.lastname: Schmidbauer
authors.forename: H
authors.initials: H
authors.lastname: Budka
authors.forename: K
authors.initials: K
authors.lastname: Kitz
authors.forename: P
authors.initials: P
authors.lastname: Grunert
authors.forename: W
authors.initials: W
authors.lastname: Koos
mesh_terms: D001254:Astrocytoma / Q000473:pathology; D001706:Biopsy / Q000379:methods*; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000473:pathology; D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D005909:Glioblastoma / Q000473:pathology; D005910:Glioma / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D013238:Stereotaxic Techniques; D014057:Tomography, X-Ray Computed
vernacular_title: Stereotaktische Biopsie intrakranieller Prozesse: Validität der histologischen Diagnostik.