title: [Chronic adrenal failure secondary to an isolated deficiency of ACTH. Presentation of 2 new cases].
abstract: Chronic adrenal failure due to hypothalamic-hypophyseal disorders is rarely encountered. This can be due to hormonal deficiencies generally related to the presence of a brain tumor or an infiltrating process and sometimes to an isolated deficiency of ACTH. We report on two patients with adrenal failure with low basal cortisol levels and a poor response to short cortisol stimulation test with ACTH. Long cortisol stimulation test with ACTH was normal and ACTH was not stimulated with corticotropin releasing factor. However, other specific dynamic pituitary hormonal tests were normal. The uncommon clinical presentation of the disease, such as severe hypoglycemic crisis and fever of unknown origin (FUO), is underscored.
authors.forename: M
authors.initials: M
authors.lastname: García de la Torre
authors.forename: M
authors.initials: M
authors.lastname: Serrano Comino
authors.forename: G
authors.initials: G
authors.lastname: Fraile Rodríguez
authors.forename: F
authors.initials: F
authors.lastname: Sánchez Franco
authors.forename: J
authors.initials: J
authors.lastname: Perales Rodríguez
authors.forename: M
authors.initials: M
authors.lastname: Serrano Ríos
mesh_terms: D000309:Adrenal Insufficiency / Q000097:blood / Q000209:etiology* / Q000503:physiopathology / Q000652:urine; D000324:Adrenocorticotropic Hormone / Q000097:blood / Q000172:deficiency*; D002908:Chronic Disease; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000652:urine; D008297:Male; D008875:Middle Aged
chemical_list: D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone
vernacular_title: Fracaso adrenal crónico secundario a deficiencia aislada de ACTH. Presentación de dos nuevos casos.