title: Chemistry and pharmacology of PAF antagonists. Evaluation of changes at potential metabolism sites on activity and duration of activity.
authors.affiliation: Platelet Biology and Chemistry, Sandoz Research Institute, East Hanover, New Jersey 07936.
authors.forename: D A
authors.initials: DA
authors.lastname: Handley
authors.forename: W J
authors.initials: WJ
authors.lastname: Houlihan
authors.forename: J C
authors.initials: JC
authors.lastname: Tomesch
authors.forename: C
authors.initials: C
authors.lastname: Farley
authors.forename: R W
authors.initials: RW
authors.lastname: Deacon
authors.forename: J M
authors.initials: JM
authors.lastname: Koletar
authors.forename: M
authors.initials: M
authors.lastname: Prashad
authors.forename: J W
authors.initials: JW
authors.lastname: Hughes
authors.forename: C
authors.initials: C
authors.lastname: Jaeggi
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D006168:Guinea Pigs; D008168:Lung / Q000187:drug effects / Q000502:physiology*; D008297:Male; D010972:Platelet Activating Factor / Q000037:antagonists & inhibitors*; D010980:Platelet Membrane Glycoproteins; D011806:Quinolinium Compounds / Q000494:pharmacology*; D011956:Receptors, Cell Surface / Q000187:drug effects; D043562:Receptors, G-Protein-Coupled; D013329:Structure-Activity Relationship
chemical_list: D010972:Platelet Activating Factor; D010980:Platelet Membrane Glycoproteins; D011806:Quinolinium Compounds; D011956:Receptors, Cell Surface; D043562:Receptors, G-Protein-Coupled; C039351:platelet activating factor receptor; C050531:SRI 63-441