title: Imaging necrotic myocardium: detection with 99mTc-pyrophosphate and radiolabeled antimyosin.
abstract: The major value of hot-spot imaging of the myocardium is its ability to define areas of necrosis rather than areas of diminished blood flow or cellular function. Applications of hot-spot imaging include the diagnosis and quantitation of myocardial infarction, myocarditis, and cardiac transplant rejection. The two agents in clinical use, 99mTc-Pyrophosphate and radiolabeled antimyosin, are discussed.
authors.affiliation: Department of Radiology, Harvard Medical School, Boston, Massachusetts.
authors.forename: B A
authors.initials: BA
authors.lastname: Khaw
authors.forename: E
authors.initials: E
authors.lastname: Haber
mesh_terms: D000818:Animals; D000906:Antibodies; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D011756:Diphosphates; D006084:Graft Rejection; D016027:Heart Transplantation; D006801:Humans; D009203:Myocardial Infarction / Q000000981:diagnostic imaging; D009205:Myocarditis / Q000000981:diagnostic imaging*; D009206:Myocardium / Q000473:pathology*; D009218:Myosins / Q000276:immunology; D009336:Necrosis; D011183:Postoperative Complications / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D013667:Technetium; D016698:Technetium Tc 99m Pyrophosphate
chemical_list: D000906:Antibodies; D011756:Diphosphates; D016698:Technetium Tc 99m Pyrophosphate; D013667:Technetium; D009218:Myosins