Impaired DNA synthesis by early pubertal cryptorchid testis in vitro.
To study the spermatogenic potential of the early pubertal cryptorchid testis, testicular DNA synthesis was examined in vitro. DNA synthesis by early pubertal cryptorchid testis was inhibited and lost its normal temperature sensitivity. The spermatogenic potential of the cryptorchid testis may be impaired as early as puberty.
Nakamura
M
M
Department of Urology, School of Medicine, Osaka University, Japan.
Nonomura
N
N
Namiki
M
M
Okuyama
A
A
Koh
E
E
Kondoh
N
N
Takeyama
M
M
Fujioka
H
H
Kiyohara
H
H
Nishimune
Y
Y
D003456:Cryptorchidism / Q000378:metabolism*; D046508:Culture Techniques; D004247:DNA / Q000096:biosynthesis*; D006801:Humans; D008297:Male; D011627:Puberty; D013091:Spermatogenesis; D013696:Temperature; D013737:Testis / Q000378:metabolism*
D004247:DNA