title: [Functional characteristics of the adrenals in the ontogeny of male water voles Arvicola terrestris with various fur colorings].
abstract: Studies have been made of the effect of colour mutations on the adrenal function in growing male voles. In postnatal life, the level of 11-oxycorticosteroids in the blood exhibited similar changes in brown (wild phenotype) and black (mutant) voles. The highest level was found in 1-2-month animals; a decrease took place to the 6th month which was followed by a secondary increase at the age of 8 months. Corticosteron production in vitro is the highest in brown males 5-month. In black voles, after 2 months the production remains unchanged, being rather high. In 5-, 6- and 8-month voles, corticosteron production in vitro increased, but not decreased after prior incubation. In mutant voles, the adrenals are more sensitive to stimulating effect of ACTH (5 units per 1 g of the adrenals) and inhibitory effect of estradiol (40 ng/100 mg) in vitro.
authors.forename: N M
authors.initials: NM
authors.lastname: Bazhan
authors.forename: L I
authors.initials: LI
authors.lastname: Ivanova
mesh_terms: D015062:11-Hydroxycorticosteroids / Q000097:blood; D000311:Adrenal Glands / Q000187:drug effects / Q000502:physiology*; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000375:Aging / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D000831:Animals, Newborn; D003411:Arvicolinae / Q000502:physiology*; D004958:Estradiol / Q000494:pharmacology; D006200:Hair Color / Q000187:drug effects / Q000502:physiology*; D006579:Heterozygote; D006720:Homozygote; D066298:In Vitro Techniques; D008297:Male; D009154:Mutation; D012621:Seasons
chemical_list: D015062:11-Hydroxycorticosteroids; D004958:Estradiol; D000324:Adrenocorticotropic Hormone
vernacular_title: Osobennosti funktsii nadpochechnikov v ontogeneze u samtsov vodianykh polevok Arvicola terrestris s razlichnoĭ okraskoĭ mekha.