[The characteristics of [3H]muscimol binding to the synaptic membranes of the cerebral cortex in the progeny of rats subjected to deprivation of the paradoxical sleep phase during pregnancy].
White rats were subjected to REM-sleep deprivation during 14-20 days of pregnancy. [3H]muscimol binding level of neocortex synaptosomal membranes was significantly higher in their offsprings as compared with the control ones. Possible ways of GABA-ergic system malformations are discussed.
Zhulin
V V
VV
Zabludovskiĭ
A L
AL
D000818:Animals; D002540:Cerebral Cortex / Q000032:analysis / Q000378:metabolism*; D005260:Female; D009118:Muscimol / Q000032:analysis / Q000378:metabolism*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D011963:Receptors, GABA-A / Q000032:analysis / Q000378:metabolism; D012892:Sleep Deprivation / Q000502:physiology*; D012895:Sleep, REM / Q000502:physiology*; D013570:Synaptic Membranes / Q000032:analysis / Q000378:metabolism*; D014316:Tritium
D011963:Receptors, GABA-A; D014316:Tritium; D009118:Muscimol
Osobennosti sviazyvaniia [3H]mustsimola s sinapticheskimi membranami kory bol'shikh polushariĭ mozga u potomstva krys, podvergavshikhsia deprivatsii paradoksal'noĭ fazy sna vo beremennosti.