Acute leukemia after adjuvant chemotherapy for breast cancer.
Alkalating chemotherapeutic agents are frequently implicated in the development of acute non-lymphocytic leukemia. A case report illustrates the danger of administering a prolonged course of adjuvant chemotherapy with Melphalan following mastectomy for breast cancer.
Gabrail
N Y
NY
D001943:Breast Neoplasms / Q000188:drug therapy*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000188:drug therapy*; D002872:Chromosome Deletion; D002897:Chromosomes, Human, Pair 7; D005260:Female; D006801:Humans; D015479:Leukemia, Myelomonocytic, Acute / Q000139:chemically induced* / Q000188:drug therapy; D008558:Melphalan / Q000009:adverse effects*; D008875:Middle Aged; D012307:Risk Factors; D013997:Time Factors
D008558:Melphalan