title: [Specific splitting of the alpha-A-globin gene by molecular forms of DNA-topoisomerase type I from calf thymus].
abstract: The specificity of splitting of the cloned alpha A-globin gene from chicken erythrocytes induced by three topoisomerases I differing in molecular masses was demonstrated. The localization and relative number of topoisomerase breaks in the alpha A-globin gene vary in different topoisomerase I forms.
authors.forename: I I
authors.initials: II
authors.lastname: Gromova
authors.forename: I B
authors.initials: IB
authors.lastname: Bronshteĭn
authors.forename: A V
authors.initials: AV
authors.lastname: Timofeev
authors.forename: S V
authors.initials: SV
authors.lastname: Razin
authors.forename: A G
authors.initials: AG
authors.lastname: Kalandadze
mesh_terms: D000818:Animals; D002417:Cattle; D002645:Chickens; D003001:Cloning, Molecular; D004247:DNA / Q000302:isolation & purification; D004264:DNA Topoisomerases, Type I / Q000378:metabolism*; D004587:Electrophoresis, Agar Gel; D004912:Erythrocytes / Q000032:analysis; D005914:Globins / Q000235:genetics* / Q000378:metabolism; D015151:Immunoblotting; D008970:Molecular Weight; D009710:Nucleotide Mapping; D010957:Plasmids
chemical_list: D005914:Globins; D004247:DNA; D004264:DNA Topoisomerases, Type I
vernacular_title: Spetsificheskoe rasshcheplenie alpha-A-globinovogo gena molekuliarnymi formami DNK-topoizomeraz I tipa iz timusa telenka.