The second messenger system as the morphogenetic field.
For sixty years morphogenetic fields have been assumed. We suggest a realization for such a field: the second messenger (in particular cyclic AMP) and its substrate (in particular ATP) are suggested to be the activator-morphogen and inhibitor respectively. Gene transcription is derived as an hysteretic function of the second messenger (cyclic AMP).
Schiffmann
Y
Y
Department of Applied Mathematics and Theoretical Physics, University of Cambridge, U.K.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000242:Cyclic AMP / Q000502:physiology; D005786:Gene Expression Regulation; D008433:Mathematics; D008954:Models, Biological; D012333:RNA, Messenger / Q000235:genetics; D015290:Second Messenger Systems; D014158:Transcription, Genetic
D012333:RNA, Messenger; D000255:Adenosine Triphosphate; D000242:Cyclic AMP