title: [Use of strong opioids in the treatment of cancer pain in adults and children].
abstract: A high percentage of adults and children with advanced cancer suffer from pain. Strong opioids for pain control, e.g. morphine, slow-released morphine or buprenorphine, should be administered early according to the intensity of pain. The analgesics should be given orally whenever possible. They must be given at fixed intervals based on the duration of their action. The dose must be titrated to the needs of the patient. Sometimes more than 1000 mg morphine orally per day is necessary. Correctly used strong opioids produce only a few side-effects, especially constipation and vomiting. Many studies in adult cancer patients all over the world demonstrate the effectiveness of strong opioids for pain control. Children should be treated in the same way and comparable data in children with cancer pain must be collected.
authors.affiliation: Zentrum Anaesthesiologie der Medizinischen Hochschule Hannover.
authors.forename: J
authors.initials: J
authors.lastname: Sorge
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000701:Analgesics, Opioid / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D004334:Drug Administration Schedule; D006801:Humans; D009369:Neoplasms / Q000503:physiopathology*; D010148:Intractable Pain / Q000188:drug therapy*
chemical_list: D000701:Analgesics, Opioid
vernacular_title: Einsatz von starken Opioiden in der Behandlung des Krebsschmerzes bei Erwachsenen und Kindern.