title: [Geographic localization of three variants of herpes simplex virus type 1 in Japan].
abstract: We previously reported that a variant of herpes simplex virus type 1 (HSV-1) designated variant type A was isolated at a much higher frequency in Western Japan than in Eastern Japan. We examined the localization of two other variant types designated B and C. The proportion of the type B and type C variants among 553 fresh HSV-1 isolates from 10 areas in Japan were 5.4% and 1.3%, respectively. The isolation frequency of type B variant in Eastern Japan was 8.3%. It was as high as 20.5% in Iwate area. The frequency in Western Japan was only 3.0%. Type C variant showed no specific geographic localization. These results were discussed in terms of characteristic mode of HSV infection and the history of the Japanese nation.
authors.forename: S
authors.initials: S
authors.lastname: Ozawa
authors.forename: K
authors.initials: K
authors.lastname: Yoshino
authors.forename: R
authors.initials: R
authors.lastname: Kawana
authors.forename: Y
authors.initials: Y
authors.lastname: Numazaki
authors.forename: T
authors.initials: T
authors.lastname: Funabashi
authors.forename: T
authors.initials: T
authors.lastname: Nakakita
authors.forename: Y
authors.initials: Y
authors.lastname: Ozaki
authors.forename: S
authors.initials: S
authors.lastname: Hata
authors.forename: T
authors.initials: T
authors.lastname: Itagaki
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
mesh_terms: D014644:Genetic Variation; D006561:Herpes Simplex / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D007564:Japan; D018139:Simplexvirus / Q000235:genetics* / Q000302:isolation & purification