Effect of vecuronium on atropine-induced changes in heart rate.
The effect of vecuronium on the heart rate response to atropine has been studied by comparing dose-response relationships in two groups of patients who underwent extracorporeal shock wave lithotripsy. One group received vecuronium (0.1 mg/kg) and the other acted as control. Incremental doses of atropine (1.8, 1.8, 3.6, 7.2 and 14.4 micrograms/kg) were administered and changes in heart rate recorded. No significant differences were observed between the two groups following each incremental dose of atropine.
Ridley
S
S
Department of Anaesthesia, St Thomas' Hospital, London.
Gaylard
D G
DG
Lim
M
M
D000328:Adult; D001285:Atropine / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D008096:Lithotripsy; D008297:Male; D014673:Vecuronium Bromide / Q000494:pharmacology*
D001285:Atropine; D014673:Vecuronium Bromide