title: Tubal patency after local methotrexate injection for tubal pregnancy.
abstract: Tubal patency was investigated by hysterosalpingography in 21 of 37 patients with unruptured tubal pregnancy treated by local methotrexate injection at laparoscopy. 18 of the 21 patients had bilateral tubal patency, and the only tube of a patient with a single fallopian tube was also patent. 6 subsequent intrauterine pregnancies have so far been recorded. Local methotrexate injection into the tubal pregnancy may provide an efficient and safe alternative to surgery in early unruptured ectopic pregnancy.
authors.affiliation: Department of Obstetrics and Gynaecology, Assaf Harofeh Medical Center, Israel.
authors.forename: M
authors.initials: M
authors.lastname: Pansky
authors.forename: I
authors.initials: I
authors.lastname: Bukovsky
authors.forename: A
authors.initials: A
authors.lastname: Golan
authors.forename: Z
authors.initials: Z
authors.lastname: Weinraub
authors.forename: D
authors.initials: D
authors.lastname: Schneider
authors.forename: R
authors.initials: R
authors.lastname: Langer
authors.forename: S
authors.initials: S
authors.lastname: Arieli
authors.forename: E
authors.initials: E
authors.lastname: Caspi
mesh_terms: D006063:Chorionic Gonadotropin / Q000097:blood; D005069:Evaluation Studies as Topic; D005186:Fallopian Tube Patency Tests / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007047:Hysterosalpingography; D007247:Infertility, Female / Q000517:prevention & control*; D015552:Injections, Intralesional; D008727:Methotrexate / Q000008:administration & dosage* / Q000627:therapeutic use; D011247:Pregnancy; D011274:Pregnancy, Tubal / Q000188:drug therapy*
chemical_list: D006063:Chorionic Gonadotropin; D008727:Methotrexate