[Metastatic liver cancer from the stomach successfully treated by combined immunochemotherapy and transarterial embolization].
A 53-year-old-man, who suffered from advanced gastric carcinoma with liver metastasis (P0H3S2N1; stage IV) underwent simple gastrectomy. After the operation, the patient was treated by chemotherapy (1/2 MFC, M: mitomycin C, F: FT-207, C: Cylocide) combined with immunotherapy (PSK, lentinan) and intraarterial injection (mitomycin C & Lipiodol). Liver metastases disappeared soon after the combined therapy, and these findings were confirmed by CT and US. Moreover, the serum level of CEA and CA 19-9 also decreased from 160 ng/ml and 51 U/ml to the normal level. The duration of the complete disappearance of the liver metastasis was not so long, but quality of life was well maintained for 2 and one half years. This case suggested that combined therapy may well be effective for advanced gastric cancer with liver metastases.
Otsuka
S
S
1st Dept. of Surgery, Kyorin University, School of Medicine.
Kitajima
M
M
Tsubuku
Y
Y
Kenmizaki
H
H
Tatekawa
I
I
Takahashi
Y
Y
D000230:Adenocarcinoma / Q000188:drug therapy / Q000556:secondary / Q000628:therapy*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003561:Cytarabine / Q000008:administration & dosage; D004621:Embolization, Therapeutic; D005472:Fluorouracil / Q000008:administration & dosage; D005743:Gastrectomy; D006499:Hepatic Artery; D006801:Humans; D007459:Iodized Oil / Q000008:administration & dosage; D007912:Lentinan / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage; D011509:Proteoglycans / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000601:surgery
D008937:Mitomycins; D011509:Proteoglycans; D003561:Cytarabine; D007912:Lentinan; C010770:polysaccharide-K; D016685:Mitomycin; D007459:Iodized Oil; D005472:Fluorouracil