title: Haemodynamic effects of vecuronium.
abstract: Three hundred and twenty adults (ASA grade I, both sexes), received diazepam 10 mg by mouth (50% received atropine 7 micrograms kg-1 in addition) i.m. 45 min before operation. Patients were then allocated randomly to undergo general anaesthesia with either a nitrous oxide-neurolept technique or nitrous oxide-halothane. Vecuronium was administered to 50% of the patients in each anaesthetic group and heart rate and arterial pressure were monitored. Vecuronium did not influence heart rate, or systolic or diastolic arterial pressures.
authors.affiliation: Research Group of the Institutes for Experimental Anesthesiology and Clinical Pharmacology, The Netherlands.
authors.forename: J M
authors.initials: JM
authors.lastname: Wierda
authors.forename: E
authors.initials: E
authors.lastname: Maestrone
authors.forename: A F
authors.initials: AF
authors.lastname: Bencini
authors.forename: A
authors.initials: A
authors.lastname: Boyer
authors.forename: O M
authors.initials: OM
authors.lastname: Rashkovsky
authors.forename: H
authors.initials: H
authors.lastname: Lip
authors.forename: R
authors.initials: R
authors.lastname: Karliczek
authors.forename: J M
authors.initials: JM
authors.lastname: Ket
authors.forename: S
authors.initials: S
authors.lastname: Agoston
mesh_terms: D000328:Adult; D000768:Anesthesia, General; D001285:Atropine / Q000494:pharmacology; D005260:Female; D006221:Halothane / Q000494:pharmacology; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008297:Male; D009458:Neuroleptanalgesia; D013997:Time Factors; D014673:Vecuronium Bromide / Q000494:pharmacology*
chemical_list: D001285:Atropine; D014673:Vecuronium Bromide; D006221:Halothane