title: Reaction of trans-2-chlorovinylarsine oxide with polydeoxynucleotides.
abstract: Trans-2-chlorovinylarsine oxide (in DCl/acetone-d6) was added to various polydeoxynucleotides. The arsenical did react with poly[dG].poly[dC], releasing guanine, and resulting in a partial apurinic duplex.
authors.affiliation: Department of Chemistry, Clemson University, SC 29634-1905.
authors.forename: K
authors.initials: K
authors.lastname: Dill
authors.forename: E R
authors.initials: ER
authors.lastname: Adams
authors.forename: S D
authors.initials: SD
authors.lastname: Davis
authors.forename: R J
authors.initials: RJ
authors.lastname: O'Connor
authors.forename: E L
authors.initials: EL
authors.lastname: McGown
authors.forename: S F
authors.initials: SF
authors.lastname: Hallowell
mesh_terms: D001152:Arsenicals / Q000378:metabolism*; D003854:Deoxyribonucleotides / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D011067:Poly dA-dT / Q000378:metabolism; D011089:Polydeoxyribonucleotides / Q000378:metabolism; D011522:Protons
chemical_list: D001152:Arsenicals; D003854:Deoxyribonucleotides; D011089:Polydeoxyribonucleotides; D011522:Protons; C016681:poly(dG).poly(dC); D011067:Poly dA-dT; C019530:poly(dC-dG); C063691:2-chlorovinylarsine oxide