title: [Is this mitral valve prolapse? A case of mitral regurgitation with early systolic murmur due to early systolic prolapse of the posterior leaflet].
abstract: This paper reports the findings of phonocardiograms, echocardiogram and Doppler echocardiograms in a case of a 50-year-old man with early mitral valve prolapse with an early systolic murmur. A characteristic early systolic crescendo murmur was recorded at the apex. By amyl nitrite inhalation, the early systolic murmur was attenuated and a late systolic murmur was evoked. On the contrary, methoxamine injection increased the intensity of the early systolic murmur. Early systolic prolapse and early systolic buckling were recorded by two-dimensional and M-mode echocardiography. The phase of mitral regurgitation detected by M-mode color Dopper echocardiography coincided well in timing with the early systolic murmur and the early systolic buckling recorded on the M-mode echocardiogram. A discussion was made on the mechanism of the early systolic mitral regurgitation due to early mitral valve prolapse.
authors.affiliation: Department of Internal Medicine, University of Tsukuba.
authors.forename: T
authors.initials: T
authors.lastname: Ishimitsu
authors.forename: Y
authors.initials: Y
authors.lastname: Hiranuma
authors.forename: Y
authors.initials: Y
authors.lastname: Sugishita
authors.forename: I
authors.initials: I
authors.lastname: Ito
mesh_terms: D000680:Amyl Nitrite; D004452:Echocardiography; D015150:Echocardiography, Doppler; D006326:Heart Auscultation; D006337:Heart Murmurs; D006801:Humans; D008297:Male; D008729:Methoxamine; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000209:etiology* / Q000503:physiopathology; D008945:Mitral Valve Prolapse / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D009200:Myocardial Contraction; D010701:Phonocardiography; D013599:Systole
chemical_list: D000680:Amyl Nitrite; D008729:Methoxamine