Determinants of polychlorinated biphenyls (PCBs), polybrominated biphenyls (PBBs), and dichlorodiphenyl trichloroethane (DDT) levels in the sera of young children.
Serum samples from 285 4-year-old Michigan children were evaluated for levels of 11 environmental contaminants. Polychlorinated biphenyls (PCBs) were found in half the samples tested; polybrominated biphenyls (PBBs) in 13-21 percent; dichlorodiphenyl trichloroethane (DDT), in more than 70 percent. Nursing (Mothers' milk) was the principal source of these exposures. Congener-specific analysis documented the presence of at least one highly toxic PCB congener, 2,3',4,4',5-pentachlorobiphenyl. The data demonstrate the multigenerational impact of female exposure to persistent organic environmental contaminants.
Jacobson
J L
JL
Psychology Department, Wayne State University, Detroit, MI 48202.
Humphrey
H E
HE
Jacobson
S W
SW
Schantz
S L
SL
Mullin
M D
MD
Welch
R
R
D001822:Body Burden; D001942:Breast Feeding; D002675:Child, Preschool; D003634:DDT / Q000097:blood*; D004781:Environmental Exposure; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D005506:Food Contamination; D006801:Humans; D008297:Male; D008423:Maternal Age; D008431:Maternal-Fetal Exchange; D011075:Polybrominated Biphenyls / Q000097:blood*; D011078:Polychlorinated Biphenyls / Q000097:blood*; D011247:Pregnancy; D012424:Rural Population; D012923:Social Class
D011075:Polybrominated Biphenyls; D003634:DDT; D011078:Polychlorinated Biphenyls