Estimation of pulsatile ocular blood flow from intraocular pressure.
A relationship has been derived between intraocular pressure and pulsatile blood flow in the eye. Measurements of intraocular pressure show a time variation that is associated with the pulsatile component of arterial pressure. Experimental results provide a means of transforming intraocular pressure changes into ocular volume changes. The eye is represented by a chamber with elastic walls, a pulsatile incoming flow of incompressible fluid (blood), and a steady outgoing flow of blood. Under these conditions, the rate of pulsatile blood flow through the eye can be approximated from the instantaneous intraocular pressure measurements. Data from a healthy human eye are used to illustrate the analysis.
Silver
D M
DM
Johns Hopkins University, Baltimore, MD.
Farrell
R A
RA
Langham
M E
ME
O'Brien
V
V
Schilder
P
P
D001783:Blood Flow Velocity; D005123:Eye / Q000033:anatomy & histology / Q000098:blood supply*; D006801:Humans; D007429:Intraocular Pressure; D011673:Pulsatile Flow; D012212:Rheology; D013997:Time Factors