[The measurement of the amount of iron (III) complexes with desferal in the perfused rat liver by an EPR method].
Rat liver was perfused by Hank's solution, containing desferal (deferoxamine). It was shown that in perfusion of the liver spectrum EPR a signal (g = 4.3; H = 63 G) appears. This signal belongs to desferal complexes, containing intracellular Fe/3/. Desferal transfer to the liver tissue and further formation of desferal complexes there takes place within first 5-10 min of liver perfusion by solution, containing 0.5 mM of desferal.
Kozlov
A V
AV
Vladimirov
Iu A
IuA
Azizova
O A
OA
D000818:Animals; D003676:Deferoxamine / Q000032:analysis*; D004578:Electron Spin Resonance Spectroscopy; D005290:Ferric Compounds / Q000032:analysis*; D008099:Liver / Q000032:analysis*; D008297:Male; D010477:Perfusion / Q000379:methods; D051381:Rats; D011919:Rats, Inbred Strains; D013053:Spectrophotometry; D013997:Time Factors
D005290:Ferric Compounds; D003676:Deferoxamine
Izmerenie kolichestva kompleksov zheleza (III) s desferalom v perfuziruemoĭ pecheni krys metodom EPR.