title: Free perforation due to colonic adenocarcinoma in Crohn's disease.
abstract: Free perforation of the bowel due to cancer in Crohn's disease is very rare. One case found among 75 cases of Crohn's disease is reported. The perforation occurred in a mucinous adenocarcinoma of the ascending colon in a 54-year-old woman with a 17-year history of Crohn's disease, who had undergone two previous operations of small bowel and colonic resection. A right hemicolectomy was performed; the patient had an uneventful recovery and does not show recurrence of cancer at 31-month follow-up. This is in contrast with a recent review, in which a very poor prognosis was claimed for the perforated colonic cancer in Crohn's disease.
authors.affiliation: Divisione di Chirurgia Generale III, Ospedale Multizonale, Varese.
authors.forename: A
authors.initials: A
authors.lastname: Fraschini
authors.forename: D
authors.initials: D
authors.lastname: Sella
authors.forename: R
authors.initials: R
authors.lastname: Gullotta
authors.forename: M
authors.initials: M
authors.lastname: Bonato
authors.forename: S
authors.initials: S
authors.lastname: Monetti
authors.forename: M
authors.initials: M
authors.lastname: Arrigo
authors.forename: G
authors.initials: G
authors.lastname: Giani
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000150:complications* / Q000473:pathology; D003082:Colectomy; D003110:Colonic Neoplasms / Q000150:complications* / Q000473:pathology; D003424:Crohn Disease / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology*; D008875:Middle Aged