Complete remission of refractory small cell carcinoma of the pancreas with cisplatin and etoposide.
A case of unusually large widespread metastatic small cell carcinoma of the pancreas is presented. The patient remains in complete remission 50 months after the diagnosis and initiation of combination chemotherapy using a schedule consisting of etoposide (150 mg/m2) intravenously (IV) on days 1 to 3 and cisplatin (100 mg) IV on day 2. Initial chemotherapy with streptozotocin, 5-fluorouracil, and methotrexate, doxorubicin, cyclophosphamide, and lomustine (MACC) had been unsuccessful.
Morant
R
R
Neoplastic Diseases and Medicine, Mount Sinai Medical Center, New York, New York.
Bruckner
H W
HW
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D018288:Carcinoma, Small Cell / Q000175:diagnosis / Q000188:drug therapy* / Q000556:secondary; D002945:Cisplatin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000188:drug therapy*; D012074:Remission Induction; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
D005047:Etoposide; D002945:Cisplatin