title: [THC-carbonic acid determination in serum with fluorescence polarization immunoassay (FPIA, TDX) and GCMS].
abstract: The Urine-Immuno-Assay (Abbot, TDX) for Cannabis you may also use for the investigation of blood or serum. First the protein is precipitated by Metanol. The solvent is removed by a gentle stream of nitrogen and the solution reconstituted with Phosphat-Buffer. You may handle this solution like urine. Confirmation analysis is made by GCMS after extraction using C-18-extraction tubes and derivation with a proper reagent. Detection limit is about 10 ng/ml. You need only 0.3 ml Serum.
authors.forename: H W
authors.initials: HW
authors.lastname: Schütz
mesh_terms: D013759:Dronabinol / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D015200:Fluoroimmunoassay; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D002189:Marijuana Abuse / Q000097:blood / Q000175:diagnosis*
chemical_list: D013759:Dronabinol; C025351:delta(9)-tetrahydrocannabinolic acid
vernacular_title: THC-Carbonsäurebestimmung im Serum mit Fluoreszens-Polarisations-Immuno-Assay (FPIA, TDX) und GCMS.