title: [Manifestation of AIDS in HIV infected homosexual males with lymphadenopathy syndrome].
abstract: 26 homosexual men with HIV-infection and lymphadenopathy syndrome were examined between 1982 and 1984 and prospectively observed over a period of 58 months (median, range 53-69 months). 16 (61.5%) developed full blown AIDS within a median period of 41 months (23-63 months). 12 of them died 50 months (median, range 29-67 months) after the first examination. 10 patients showed no symptoms of AIDS after a median observation time of 57 months (54-63 months). A panel of clinical symptoms, signs of concomitant infections, chemical and immunological analyses, including a lymphnode biopsy were correlated to the course of the disease. A decreased proportion of CD4-cells and a lower CD4/CD8 ratio in the lymphnode suspensions at the first examination in patients with disease progression were the only parameter which correlated significantly with the development of AIDS.
authors.affiliation: Medizinische Universitätsklinik III der Universität Erlangen-Nürnberg.
authors.forename: T
authors.initials: T
authors.lastname: Harrer
authors.forename: K
authors.initials: K
authors.lastname: Messing
authors.forename: U
authors.initials: U
authors.lastname: Bienzle
authors.forename: E
authors.initials: E
authors.lastname: Meyer
authors.forename: J
authors.initials: J
authors.lastname: Giedl
authors.forename: J R
authors.initials: JR
authors.lastname: Kalden
mesh_terms: D000386:AIDS-Related Complex / Q000175:diagnosis* / Q000276:immunology; D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis* / Q000276:immunology; D000328:Adult; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D005500:Follow-Up Studies; D015483:HIV Antibodies / Q000032:analysis; D006679:HIV Seropositivity / Q000175:diagnosis*; D015497:HIV-1 / Q000276:immunology / Q000472:pathogenicity*; D006716:Homosexuality; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
chemical_list: D015483:HIV Antibodies
vernacular_title: Manifestation von AIDS in HIV-infizierten homosexuellen Männern mit Lymphadenopathie-Syndrom (LAS).