Relationships between renal hemodynamics and plasma levels of arginine vasotocin and mesotocin during hemorrhage in the domestic fowl (Gallus domesticus).
1. Renal tissue blood flow (renal perfusion) and plasma levels of arginine vasotocin (AVT) and mesotocin (MT) were measured in anesthetized chickens before and during hemorrhage. 2. Renal perfusion did not decrease (P less than 0.05) until nearly 50% of the blood volume had been removed. The decrease in renal perfusion was not related to arterial blood pressure but was concomitant with an increase (P less than 0.05) in plasma AVT levels. 3. Renal perfusion during hemorrhage was positively correlated with plasma MT levels by the regression equation: renal perfusion = 0.091 (MT)-1.1459 which was highly significant (P less than 0.001, r2 = 0.95). 4. The results of this study suggest that MT as well as AVT may participate in regulating blood flow in the avian kidney.
Bottje
W G
WG
Department of Animal Sciences, University of Arkansas, Fayetteville 72701.
Holmes
K R
KR
Neldon
H L
HL
Koike
T K
TK
D000818:Animals; D002645:Chickens / Q000502:physiology*; D006439:Hemodynamics; D006470:Hemorrhage / Q000097:blood / Q000503:physiopathology / Q000662:veterinary*; D007668:Kidney / Q000098:blood supply*; D008297:Male; D010121:Oxytocin / Q000031:analogs & derivatives* / Q000097:blood; D011201:Poultry Diseases / Q000097:blood / Q000503:physiopathology*; D014668:Vasotocin / Q000097:blood*
C001713:mesotocin; D010121:Oxytocin; D014668:Vasotocin