[Stimulation of sodium transport by cobalt ions in the skin of amphibia against a background of aldosterone action].
Sodium transport across toad Bufo marinus and frog Rana temporaria skin was enhanced by aldosterone added to Ringer solution at the basal plasma membrane. Cobalt ions applied to the outer surface of amphibian skin have increased sodium transport stimulated by aldosterone. The regulatory sites of the sodium channel macromolecule seem to be located on both surfaces of the channel apical membrane.
Crabbé
J
J
Natochin
Iu V
IuV
D000450:Aldosterone / Q000494:pharmacology*; D000663:Amphibians / Q000378:metabolism*; D000818:Animals; D001692:Biological Transport / Q000187:drug effects / Q000502:physiology; D002024:Bufo marinus; D003035:Cobalt / Q000494:pharmacology*; D011896:Rana temporaria; D012867:Skin / Q000187:drug effects* / Q000378:metabolism; D012964:Sodium / Q000378:metabolism*; D015222:Sodium Channels / Q000187:drug effects / Q000502:physiology; D012979:Sodium Radioisotopes; D013268:Stimulation, Chemical
D015222:Sodium Channels; D012979:Sodium Radioisotopes; D003035:Cobalt; D000450:Aldosterone; D012964:Sodium
Stimuliatsiia transporta natriia ionami kobal'ta v kozhe amfibiĭ na fone deĭstviia al'dosterona.