Antifungal activity of diethyldithiocarbamate.
Sodium diethyldithiocarbamate (DTC) was evaluated for its ability to combat four different species of fungi in vitro. Using a microtiter-broth-dilution method we were able to demonstrate an antifungal activity against Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus and Mucor mucedo in doses achievable by intravenous administration in man.
Allerberger
F
F
Reisinger
E C
EC
Söldner
B
B
Dierich
M P
MP
D001232:Aspergillus fumigatus / Q000187:drug effects*; D002176:Candida albicans / Q000187:drug effects*; D003454:Cryptococcus; D003455:Cryptococcus neoformans / Q000187:drug effects*; D004050:Ditiocarb / Q000494:pharmacology*; D009089:Mucor / Q000187:drug effects*
D004050:Ditiocarb