In vitro studies into some parameters of protein and carbohydrate metabolism in lymphocytes infected with bovine leucosis virus.
Several parameters of protein and carbohydrate metabolism were determined in normal and leukemic lymphocytes in vitro in cattle, including arylamidase activity toward beta-naphthylamides of L-amino acids. The homogenate of bovine leukemic lymphocytes, in comparison with the control revealed increase of gamma-glutamyltransferase, activity trypsin inhibitor and papain inhibitor concentration and aldolase activity. On the other hand, proteolytic activity toward casein and histomucoid content decreased. Out of the 7 substrates used in the study, only 2, alanyl-beta-naphthylamide and leucyl-beta-naphthylamide, demonstrated lower activity in the leukemic material. Disorders in carbohydrate and protein metabolism in the observed lymphocytes in vitro in cattle are presented in the paper.
Madej
J A
JA
Sobiech
K A
KA
Klimentowski
S
S
D000818:Animals; D050260:Carbohydrate Metabolism; D002417:Cattle; D002418:Cattle Diseases / Q000378:metabolism*; D002478:Cells, Cultured; D005260:Female; D007938:Leukemia / Q000378:metabolism / Q000662:veterinary*; D001909:Leukemia Virus, Bovine; D008214:Lymphocytes / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism*
D011506:Proteins