Glycine reverses 7-Cl kynurenate blockade of glutamate neurotoxicity in cell culture.
Shalaby
I
I
Pfizer Central Research, Groton, CT 06340.
Chenard
B
B
Prochniak
M
M
D000818:Animals; D002478:Cells, Cultured; D004347:Drug Interactions; D005971:Glutamates / Q000633:toxicity*; D005998:Glycine / Q000494:pharmacology*; D006624:Hippocampus / Q000166:cytology / Q000187:drug effects*; D007736:Kynurenic Acid / Q000031:analogs & derivatives* / Q000494:pharmacology; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D009410:Nerve Degeneration / Q000187:drug effects; D051381:Rats; D016194:Receptors, N-Methyl-D-Aspartate; D017981:Receptors, Neurotransmitter / Q000187:drug effects
D005971:Glutamates; D016194:Receptors, N-Methyl-D-Aspartate; D017981:Receptors, Neurotransmitter; D007770:L-Lactate Dehydrogenase; D007736:Kynurenic Acid; C057013:7-chlorokynurenic acid; D005998:Glycine