Multiple action compounds in angina pectoris.
Carvedilol--a vasodilating beta-blocker has been shown in multicentre trials to be as effective as standard beta-blockers in improving exercise tolerance in patients with angina pectoris and it is more effective than nifedipine. The side effects are less than conventional beta-blockers and nifedipine. Carvedilol is an effective anti-anginal therapy and improves the quality of life.
Kelly
D T
DT
Hallstrom Institute of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia.
Freedman
S B
SB
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000787:Angina Pectoris / Q000188:drug therapy* / Q000503:physiopathology; D002227:Carbazoles / Q000627:therapeutic use*; D000077261:Carvedilol; D006801:Humans; D011412:Propanolamines / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use*
D000319:Adrenergic beta-Antagonists; D002227:Carbazoles; D011412:Propanolamines; D014665:Vasodilator Agents; D000077261:Carvedilol