[The role of the endothelium in the reactions of the vascular wall to mechanical stretching and the action of neuromediators].
In isolated rings of the rat aorta, the responses of the smooth muscles to mechanical stretching were studied: the endothelium cells potentiated the relaxation under the stretching. After removal of endothelium cells, acetylcholine induced contraction of the smooth muscle.
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D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D004730:Endothelium, Vascular / Q000187:drug effects / Q000502:physiology* / Q000648:ultrastructure; D066298:In Vitro Techniques; D008854:Microscopy, Electron; D009119:Muscle Contraction / Q000187:drug effects; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000502:physiology* / Q000648:ultrastructure; D018377:Neurotransmitter Agents / Q000494:pharmacology*; D009638:Norepinephrine / Q000494:pharmacology; D010812:Physical Stimulation; D051381:Rats
D018377:Neurotransmitter Agents; D000109:Acetylcholine; D009638:Norepinephrine
Rol' éndoteliia v reaktsiiakh sosudistoĭ stenki na mekhanicheskoe rastiazhenie i deĭstvie neĭromediatorov.