title: Adjunctive buspirone in benzodiazepine treatment of four patients with panic disorder.
abstract: Four patients with panic disorder whose panic attacks responded to benzodiazepine treatment but who suffered persistent anxiety improved after addition of buspirone. Despite its lack of antipanic effect, buspirone may offer an adjunctive benefit when added to benzodiazepines in panic disorder.
authors.affiliation: Clinical Psychopharmacology Unit, Massachusetts General Hospital, Boston 02114.
authors.forename: D R
authors.initials: DR
authors.lastname: Gastfriend
authors.forename: J F
authors.initials: JF
authors.lastname: Rosenbaum
mesh_terms: D000328:Adult; D000525:Alprazolam / Q000627:therapeutic use; D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D001007:Anxiety / Q000188:drug therapy; D002065:Buspirone / Q000627:therapeutic use*; D002998:Clonazepam / Q000627:therapeutic use; D003975:Diazepam / Q000627:therapeutic use; D004338:Drug Combinations; D005239:Fear / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010200:Panic / Q000187:drug effects*; D010698:Phobic Disorders / Q000188:drug therapy
chemical_list: D014151:Anti-Anxiety Agents; D004338:Drug Combinations; D002998:Clonazepam; D003975:Diazepam; D002065:Buspirone; D000525:Alprazolam