title: [Antigenic structure of the foot-and-mouth virus. V. Protection of naturally susceptible animals from foot-and-mouth disease using a synthetic peptide].
abstract: We have synthesized the peptide representing 135-159 VP1 sequence of A22 strain of the foot-and-mouth disease virus (FMDV). The synthetic peptide induced 100% protection of guinea pigs against the disease. Two-fold immunization of cuttle with the peptide and single immunization of sheep induced full protection of the animals against A22 strain of FMDV.
authors.forename: A V
authors.initials: AV
authors.lastname: Iarov
authors.forename: V M
authors.initials: VM
authors.lastname: Gel'fanov
authors.forename: L A
authors.initials: LA
authors.lastname: Grechaninova
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Surovoĭ
authors.forename: O M
authors.initials: OM
authors.lastname: Vol'pina
authors.forename: V T
authors.initials: VT
authors.lastname: Ivanov
authors.forename: A V
authors.initials: AV
authors.lastname: Chepurkin
authors.forename: N N
authors.initials: NN
authors.lastname: Driagalin
authors.forename: V M
authors.initials: VM
authors.lastname: Ivaniushchenkov
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000956:Antigens, Viral; D005537:Aphthovirus / Q000276:immunology*; D002417:Cattle; D004198:Disease Susceptibility; D005536:Foot-and-Mouth Disease / Q000517:prevention & control*; D006168:Guinea Pigs; D007114:Immunization; D008969:Molecular Sequence Data; D010455:Peptides / Q000276:immunology*; D012756:Sheep
chemical_list: D000956:Antigens, Viral; D010455:Peptides
vernacular_title: Antigennaia struktura virusa iashchura. V. Zashchita prirodonovospriimchivykh zhivotnykh ot zabolevaniia iashchurom s pomoshch'iu sinteticheskogo peptida.