[ACTH and cortisol after cigarette smoke exposure during the dexamethasone suppression test in smokers and non-smokers].
In this research the effect of nicotine, (smoke of cigarette), was studied in smokers and non smokers during dexamethasone inhibitory test (1 mg h 23.00). ACTH and cortisol plasma levels, physiologically suppressed at 08.00, increased, after 30 min from smoking, only in group of non smokers. These data suggest that nicotine, in non smokers, could induce a maximum stimulus on diencephalic structures, so to overcome the inhibition of dexamethasone.
Sellini
M
M
Sartori
M P
MP
Baccarini
S
S
Bassi
R
R
Dimitriadis
E
E
D000324:Adrenocorticotropic Hormone / Q000097:blood*; D000328:Adult; D003907:Dexamethasone; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects; D008297:Male; D010913:Pituitary-Adrenal System / Q000187:drug effects; D012907:Smoking / Q000097:blood*; D014028:Tobacco Smoke Pollution
D014028:Tobacco Smoke Pollution; D003907:Dexamethasone; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone
Studio dell'ACTH e del cortisolo dopo fumo di sigaretta, nel corso della prova di inibizione con desametasone, in fumatori e non fumatori.