title: [Morphofunctional changes of the neurosecretory system and microcirculatory bed of the hypothalamus in patients with chronic alcoholic intoxication of varying degree].
abstract: Microcirculation was studied in the hypothalamus in acute alcohol intoxication. Blood flow was sharply decelerated with capillaries paretically dilated, overfilled with blood. Stasis, sludge formation and venue microthrombosis were directly related to the alcohol concentration in blood and urine. In neurosecretion areas the hemorrhagic sites were detected with neurosecretory cells activity sharply reduced. Chronical alcohol administration increased the number of functionally inactivated capillaries. These with luminal vesiculation were also found as were lymphoid cell infiltrates in venule walls. The number of capillaries inactivated in the neurosecretory system paralleled the number of dark cells that reflected the inhibition effects.
authors.forename: N K
authors.initials: NK
authors.lastname: Bogdanovich
mesh_terms: D000328:Adult; D000435:Alcoholic Intoxication / Q000473:pathology / Q000503:physiopathology; D000437:Alcoholism / Q000473:pathology* / Q000503:physiopathology; D000886:Anthropometry; D002196:Capillaries / Q000473:pathology; D002452:Cell Count; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism / Q000473:pathology*; D007031:Hypothalamus / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D018377:Neurotransmitter Agents / Q000378:metabolism
chemical_list: D018377:Neurotransmitter Agents
vernacular_title: Morfofunktsional'nye izmeneniia neirosekretornoĭ sistemy i mikrotsirkuliatornogo rusla gipotalamusa u lits s khronicheskoĭ alkogol'noĭ intoksikatsieĭ raznoĭ stepeni.