[A study of the effect of thymotropin on immunologic indicators and excretion of virus in women with chronic cytomegalovirus infection].
Thymotropic hormone was given subcutaneously in a dose of 100 mg twice a week for 3 months to 10 women with verified chronic cytomegalovirus infection. After termination of the treatment, in 8 women the virus excretion was decreased and this was accompanied with some improvement in immunological parameters: increased activity of natural killers, enhanced interferon-producing activity of lymphocytes, higher theophylline-resistant lymphocytes, and lower theophylline-sensitive T-cells. The above results confirm the association between the activity of cytomegalovirus infection and the state of immunity and allow thymotropic hormone to be recommended for treatment of other groups of patients with cytomegalovirus infection.
Savitskiĭ
G I
GI
Morgunov
K V
KV
Farber
N A
NA
Grishchenko
S V
SV
Martynova
V N
VN
Ketiladze
E S
ES
Ershov
F I
FI
Parshina
O V
OV
Demidova
S A
SA
D002908:Chronic Disease; D003587:Cytomegalovirus / Q000502:physiology*; D003586:Cytomegalovirus Infections / Q000188:drug therapy / Q000276:immunology / Q000382:microbiology*; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007694:Killer Cells, Natural / Q000187:drug effects; D013601:T-Lymphocytes / Q000187:drug effects; D013951:Thymus Hormones / Q000494:pharmacology* / Q000627:therapeutic use
D013951:Thymus Hormones
Izuchenie vliianiia timotropina na immunologicheskie pokazateli i ékskretsiiu virusa u zhenshchin s khronicheskoĭ tsitomegalovirusnoĭ infektsieĭ.