Distribution of angiotensin I converting enzyme in male reproductive systems of various vertebrates and properties of the genital enzymes.
The distribution of the angiotensin I converting enzyme (EC 3.4.15.1, ACE) in male reproductive systems of various vertebrates including non-mammalian species and properties of the genital ACEs were studied. In such mammals as rat, dog and pig, it has been found that ACE activity is only distributed in testis and epididymis (especially in the epididymal semen), but not in accessory sex glands such as prostate, seminal vesicle and coagulating gland. In the rat and dog, most of or all epididymal ACE has been found to resemble testicular ACEs rather than pulmonary ACE in molecular weight. Besides the studies on mammals, it has been found that the enzymes having characteristics of ACE are present in the genital systems of such lower vertebrates as bird (domestic fowl) and fish (carp).
Yamaguchi
T
T
Department of Biochemistry, Science University of Tokyo, Japan.
Ikekita
M
M
Kizuki
K
K
Moriya
H
H
D000818:Animals; D002347:Carps; D002645:Chickens; D004285:Dogs; D004822:Epididymis / Q000201:enzymology; D005837:Genitalia, Male / Q000201:enzymology*; D007700:Kinetics; D008297:Male; D009928:Organ Specificity; D007703:Peptidyl-Dipeptidase A / Q000032:analysis*; D011467:Prostate / Q000201:enzymology; D051381:Rats; D012669:Seminal Vesicles / Q000201:enzymology; D013045:Species Specificity; D013552:Swine; D013737:Testis / Q000201:enzymology; D014714:Vertebrates / Q000378:metabolism*
D007703:Peptidyl-Dipeptidase A