Progesterone in saliva as an index of ovarian function.
Progesterone was assayed in samples of saliva collected daily throughout the menstrual cycle and correlated with corresponding daily concentrations of pregnanediol-3 alpha-glucuronide in early morning urine. Ovarian follicular growth was monitored on a daily basis with a real-time sector scanner. The concentrations of salivary progesterone shows a specific pattern with a mid-cycle rise and a peak in the luteal phase. The mean concentration in the follicular phase, as determined, was 40.4 pmol/l (range 15.3-110.7 pmol/l). It increased in the peri-ovulatory period to a peak of 201.1 pmol/l (range 46.4-289.8 pmol/l) 6 days following follicular rupture.
Adekunle
A O
AO
Department of Obstetrics and Gynecology, University College Hospital, Ibadan, Nigeria.
Kim
J B
JB
Collins
W P
WP
Whitehead
M I
MI
D000328:Adult; D005260:Female; D006801:Humans; D007118:Immunoassay / Q000379:methods; D008597:Menstrual Cycle; D010053:Ovary / Q000502:physiology*; D011276:Pregnanediol / Q000031:analogs & derivatives / Q000652:urine; D011374:Progesterone / Q000032:analysis*; D011863:Radioimmunoassay; D012463:Saliva / Q000032:analysis*
C022270:pregnanediol-3 alpha-glucuronide; D011374:Progesterone; D011276:Pregnanediol