[The hemagglutinating properties and adsorption on erythrocytes of Coxsackie B-3 viruses and their selected bentonite variants].
The paper is devoted to the study of the Coxsackie B-3 viruses and their bentonite variants passaged on the primary and transplanted cell cultures for their hemagglutinating (HA) properties and a degree of adsorption on erythrocytes. It is shown possible to detect the HA activity of the Coxsackie B-3 viruses which are passaged on the transplanted cell cultures: the variant Abent has the hemagglutinating activity relative to human and rabbit erythrocytes. The variant Abent+ of the Coxsackie B-3 virus passaged on the cell culture Vero is established not to be absorbed on erythrocytes. The variant Abent and the initial population of the Coxsackie B-3 virus are adsorbed on the human erythrocytes by 90-99%. Coxsackie B-3 virus and its bentonite variants reproduced on the primary cell culture of human embryonic fibroblasts and possessing the hemagglutinating activity are 100-1000 times better adsorbed on human erythrocytes than the viruses passaged in the transplanted culture.
Shirobokov
V P
VP
Egorov
A A
AA
Ambartsumova
N V
NV
D000327:Adsorption; D000818:Animals; D001546:Bentonite; D004622:Embryo, Mammalian; D029822:Enterovirus B, Human / Q000472:pathogenicity*; D004912:Erythrocytes / Q000382:microbiology*; D014644:Genetic Variation; D006387:Hemagglutination, Viral / Q000502:physiology*; D006801:Humans; D012641:Selection, Genetic; D012692:Serial Passage; D014709:Vero Cells; D014776:Virus Cultivation
D001546:Bentonite
Izuchenie gemaggliutiniruiushchikh svoĭstv i adsorbtsii na éritrotsitakh virusov Koksaki B-3 i ikh selektsionirovannykh bentonitovykh variantov.