The European experience with antihistamines in asthma.
Until the appearance of nonsedating antihistamines such as terfenadine and astemizole, clinical studies of H1 antagonists in the treatment of asthma yielded disappointing results. The author reviews recent European studies that demonstrate terfenadine's effectiveness in reducing symptoms and improving bronchodilation in patients with mild atopic asthma.
Rafferty
P
P
Department of Respiratory Medicine, Western Infirmary, Glasgow, Scotland.
D001249:Asthma / Q000188:drug therapy*; D001559:Benzhydryl Compounds; D002744:Chlorpheniramine / Q000627:therapeutic use; D005060:Europe; D005541:Forced Expiratory Volume; D006634:Histamine H1 Antagonists / Q000627:therapeutic use*; D006801:Humans; D016593:Terfenadine
D001559:Benzhydryl Compounds; D006634:Histamine H1 Antagonists; D002744:Chlorpheniramine; D016593:Terfenadine