[The family of env genes of avian retroviruses: molecular analysis of Rous sarcoma virus adapted to duck cells].
For the elucidation of the molecular basis of RSV adaptation to conditionally permissive host from the genome library of duck embryo fibroblasts, transformed by Rous sarcoma virus in 30 passages on these cells, recombinant bacteriophages that include provirus sequences, were obtained. Complete and transformation-defective proviruses were characterized, nucleotide sequences of their env-genes were compared with their counterparts the original RSV (Pr-RSV-C) and with viruses of other subgroups (A, B, D and E). The possible relation of the revealed changes in domains coding gp85 and gp37, with the changes of chicken RSV characteristics during adaptation to duck cells is discussed.
Ryndich
A V
AV
Kashuba
V I
VI
Kavsan
V M
VM
Zubak
S V
SV
Hlozanek
I
I
D000818:Animals; D001358:Avian Sarcoma Viruses / Q000235:genetics*; D001483:Base Sequence; D002472:Cell Transformation, Viral / Q000235:genetics*; D002478:Cells, Cultured; D002645:Chickens; D004372:Ducks; D005347:Fibroblasts; D015686:Gene Products, env / Q000235:genetics*; D015752:Genes, env; D008969:Molecular Sequence Data; D009856:Oncogene Proteins, Viral / Q000235:genetics*; D014759:Viral Envelope Proteins / Q000235:genetics*
D015686:Gene Products, env; D009856:Oncogene Proteins, Viral; C062390:Rous sarcoma virus envelope protein gp37; C062389:Rous sarcoma virus envelope protein gp85; D014759:Viral Envelope Proteins
Semeĭstvo genov env ptich'ikh retrovirusov: molekuliarnyĭ analiz virusa sarkomy Rausa, adaptirovannogo k utinym kletkam.