title: Combined hepatocellular-cholangiocarcinoma associated with dermatomyositis.
abstract: A 56 year old female developed combined hepatocellular cholangiocarcinoma associated with dermatomyositis. Serum tumour markers except for carbohydrate antigen (CA 19-9; 6400 ng/ml) were within normal range. Despite extensive chemotherapy, no clinical response was obtained and the patient's course deteriorated after 4 months. Macroscopically, the liver was mainly occupied by hepatocellular carcinoma but cholangiocarcinoma was found in the hilum. This is the first case of a rare association of combined hepatocellular-cholangiocarcinoma and dermatomyositis.
authors.affiliation: Second Department of Internal Medicine, Tottori University School of Medicine, Yonago, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Horie
authors.forename: M
authors.initials: M
authors.lastname: Yamada
authors.forename: K
authors.initials: K
authors.lastname: Nakai
authors.forename: H
authors.initials: H
authors.lastname: Kawasaki
authors.forename: C
authors.initials: C
authors.lastname: Hirayama
authors.forename: K
authors.initials: K
authors.lastname: Matsui
authors.forename: N
authors.initials: N
authors.lastname: Kambe
authors.forename: S
authors.initials: S
authors.lastname: Shimao
mesh_terms: D002759:Adenoma, Bile Duct / Q000150:complications* / Q000473:pathology; D006528:Carcinoma, Hepatocellular / Q000150:complications* / Q000473:pathology; D003882:Dermatomyositis / Q000150:complications*; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000150:complications* / Q000473:pathology; D008875:Middle Aged