[A study on the relationship between reduced activity of red cell membrane sodium-potassium pump and essential hypertension].
A population-based matched study of 103 pairs on the relation of sodium-potassium pump defect and hypertension was conducted at a factory in 1986. Conditional Logistic regression technique was used in data analysis. It was suggested that the increase of RBCNa+ and decrease of RBCK+ and RBCNa+, K+ATP-ase were significantly associated with hypertension. Plasma sodium and body weight, which were considered as important risk factors of hypertension, were fund correlated with the decrease of RBCNa+, K+ATPase, it was proposed that reduced activity of cell membrane sodium-potassium pump might be the common link of the two factors with hypertension.
Li
H X
HX
D000328:Adult; D004910:Erythrocyte Membrane / Q000201:enzymology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D008297:Male; D011188:Potassium / Q000378:metabolism; D012044:Regression Analysis; D012964:Sodium / Q000378:metabolism; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*
D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase; D011188:Potassium