title: Serum immunoglobulin A response to Norwalk virus infection.
abstract: We describe the serum immunoglobulin A (IgA) antibody response to Norwalk virus infection in human volunteers and compare it with previously described IgM and total antibody responses. Whereas specific IgA and IgM peak within 2 weeks after onset of symptoms, titers of total blocking antibody continue to rise, implying mediation by IgG antibody.
authors.affiliation: Division of Viral Diseases, Centers for Disease Control, Atlanta, Georgia 30333.
authors.forename: D D
authors.initials: DD
authors.lastname: Erdman
authors.forename: G W
authors.initials: GW
authors.lastname: Gary
authors.forename: L J
authors.initials: LJ
authors.lastname: Anderson
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis / Q000096:biosynthesis; D001667:Binding, Competitive; D005759:Gastroenteritis / Q000276:immunology*; D006801:Humans; D007118:Immunoassay; D007070:Immunoglobulin A / Q000032:analysis / Q000096:biosynthesis*; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis / Q000096:biosynthesis; D007700:Kinetics; D009663:Norwalk virus / Q000276:immunology*; D014777:Virus Diseases / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M