Influence of capsaicin-sensitive fibres on experimentally-induced colitis in rats.
Systemic capsaicin pretreatment worsens trinitrobenzene sulphonic acid-induced colitis but has no effect on colitis induced by ethanol or acetic acid. The influence of capsaicin-sensitive fibres on experimentally-induced colitis seems to depend upon the type of ulcerogenic stimuli in relation to its chronic nature.
Evangelista
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S
Pharmacology Department, Menarini Pharmaceuticals, Firenze, Italy.
Meli
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A
D000085:Acetates; D000818:Animals; D002211:Capsaicin / Q000494:pharmacology*; D003092:Colitis / Q000139:chemically induced / Q000503:physiopathology*; D000431:Ethanol; D008297:Male; D009474:Neurons / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains; D014302:Trinitrobenzenesulfonic Acid
D000085:Acetates; D000431:Ethanol; D014302:Trinitrobenzenesulfonic Acid; D002211:Capsaicin