title: Arctic life adaptation--I. The function of reindeer hemoglobin.
abstract: 1. The functional properties of hemoglobin from the reindeer (Rangifer tarandus tarandus L.) are characterized as a function of pH, temperature and organic phosphate concentration. 2. Alongside overall similarities shared with most vertebrate hemoglobins, hemoglobin from the reindeer shows significant differences with respect to the effect of both organic phosphates and chloride anions. 3. The limited effect of temperature on oxygen binding (delta H = -4 kcal/mol O2) could be regarded as an interesting case of molecular adaptation to extreme environmental conditions.
authors.affiliation: Department of Experimental Medicine and Biochemical Sciences, II University of Rome, Italy.
authors.forename: B
authors.initials: B
authors.lastname: Giardina
authors.forename: S G
authors.initials: SG
authors.lastname: Condò
authors.forename: S
authors.initials: S
authors.lastname: el Sherbini
authors.forename: S
authors.initials: S
authors.lastname: Mathisen
authors.forename: N
authors.initials: N
authors.lastname: Tyler
authors.forename: M
authors.initials: M
authors.lastname: Nuutinen
authors.forename: A
authors.initials: A
authors.lastname: Bårdgard
authors.forename: O
authors.initials: O
authors.lastname: Brix
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D001110:Arctic Regions; D001797:Blood Protein Electrophoresis; D002712:Chlorides / Q000032:analysis; D004163:Diphosphoglyceric Acids / Q000494:pharmacology; D006454:Hemoglobins / Q000032:analysis / Q000378:metabolism / Q000502:physiology*; D006863:Hydrogen-Ion Concentration; D007295:Inositol Phosphates / Q000494:pharmacology; D010100:Oxygen / Q000378:metabolism; D012053:Reindeer / Q000097:blood*; D013696:Temperature
chemical_list: D002712:Chlorides; D004163:Diphosphoglyceric Acids; D006454:Hemoglobins; D007295:Inositol Phosphates; D010100:Oxygen