Does urinary salbutamol reflect compliance with the aerosol regimen in patients with asthma?
Compliance with inhaled beta agonist therapy in a group of asthmatic patients in general practice has been monitored using a high performance thin layer chromatographic assay of salbutamol in urine. Urine salbutamol levels were lower than expected in five of 51 patients and much higher than expected in a further 11 patients. These results suggest the assay may be clinically useful for monitoring compliance of asthmatic patients with inhaled salbutamol.
Horn
C R
CR
Department of Thoracic Medicine, Guy's Hospital, London, U.K.
Essex
E
E
Hill
P
P
Cochrane
G M
GM
D000336:Aerosols; D000420:Albuterol / Q000627:therapeutic use / Q000652:urine*; D001249:Asthma / Q000188:drug therapy*; D002855:Chromatography, Thin Layer; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D012016:Reference Values
D000336:Aerosols; D000420:Albuterol