Neuroblastoma in an adult causing spinal cord compression: report of a case and review of the literature.
Adult neuroblastoma (ANB) is an uncommon malignancy, there being only 42 reported cases in the world literature. The purpose of this report is to present a case of ANB with spinal cord compression by an intraspinal component, and review methods of diagnosis and treatment. NB is one of the most frequent childhood malignancies (90% of the patients are less than 10 years old) and both pathologists and clinicians tend to exclude it from differential diagnosis when the patient is an adult. When the tumour is located in the paraspinal region, local extension through the intervertebral foramen into the spinal canal can occur in a dumbbell fashion, a pattern of growth first described by Weber in 1856.
Urios
J I
JI
Hospital de Traumatologia y Rehabilitación, C. S. Vall d'Hebron, Barcelona, Spain.
Garceran
L R
LR
Rosell
T V
TV
D000328:Adult; D006801:Humans; D008297:Male; D009447:Neuroblastoma / Q000150:complications* / Q000473:pathology / Q000532:radiotherapy; D013117:Spinal Cord Compression / Q000209:etiology*; D013125:Spinal Neoplasms / Q000150:complications* / Q000473:pathology / Q000532:radiotherapy