Growth and development in thanatophoric dysplasia.
Two cases of prolonged survival of thanatophoric dysplasia are presented, in which ventilatory support was initiated in the neonatal period because of respiratory distress. Both patients required a ventriculoperitoneal shunt for hydrocephalus and had decompression of the posterior fossa. The history of each patient has been characterized by profound developmental delay and dramatic growth failure.
MacDonald
I M
IM
Department of Ophthalmology, Childrens' Hospital of Eastern Ontario, Ottawa, Canada.
Hunter
A G
AG
MacLeod
P M
PM
MacMurray
S B
SB
D001132:Arm / Q000000981:diagnostic imaging; D001827:Body Height; D001835:Body Weight; D001846:Bone Development; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006849:Hydrocephalus; D007866:Leg / Q000000981:diagnostic imaging; D008297:Male; D010009:Osteochondrodysplasias / Q000503:physiopathology*; D011859:Radiography; D013131:Spine / Q000000981:diagnostic imaging; D013796:Thanatophoric Dysplasia / Q000503:physiopathology*