title: Effects of pure interferons on Epstein-Barr virus infection in vitro.
abstract: Pure human gamma-interferon as well as alpha-interferon inhibited induction of immunoglobulin synthesis by Epstein-Barr virus but not by pokeweed mitogen in B lymphocytes from adult but not from newborn humans. The interferons inhibited the infected B lymphocytes directly, irrespective of the Epstein-Barr virus immune status of the donor, and their inhibitory effect was synergistic.
authors.forename: J P
authors.initials: JP
authors.lastname: Andersson
authors.forename: U G
authors.initials: UG
authors.lastname: Andersson
authors.forename: I T
authors.initials: IT
authors.lastname: Ernberg
authors.forename: S F
authors.initials: SF
authors.lastname: Britton
authors.forename: M
authors.initials: M
authors.lastname: DeLey
mesh_terms: D000956:Antigens, Viral / Q000032:analysis; D019309:Epstein-Barr Virus Nuclear Antigens; D004854:Herpesvirus 4, Human / Q000276:immunology*; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D007372:Interferons / Q000494:pharmacology*; D008214:Lymphocytes / Q000382:microbiology
chemical_list: D000956:Antigens, Viral; D019309:Epstein-Barr Virus Nuclear Antigens; D007075:Immunoglobulin M; D007372:Interferons