title: Comparison of 6- with 9-week trials of adjunctive imipramine in postpsychotic depression.
abstract: Outcome at 6 weeks versus outcome at 9 weeks was compared in 23 patients with syndromally defined episodes of postpsychotic depression who underwent a trial of adjunctive imipramine added to their continuing treatment with fluphenazine decanoate and benztropine. The global outcome after 9 weeks was found to be superior. The implications of this finding for the treatment of secondary depressions in patients with schizophrenia and schizoaffective disorder is discussed.
authors.affiliation: Hillside Hospital Division, Long Island Jewish Medical Center, NY.
authors.forename: S G
authors.initials: SG
authors.lastname: Siris
authors.forename: F
authors.initials: F
authors.lastname: Adan
authors.forename: A
authors.initials: A
authors.lastname: Strahan
authors.forename: A
authors.initials: A
authors.lastname: Aronson
authors.forename: J
authors.initials: J
authors.lastname: Mandeli
authors.forename: B
authors.initials: B
authors.lastname: Fasano-Dube
mesh_terms: D000328:Adult; D000341:Affective Disorders, Psychotic / Q000188:drug therapy* / Q000523:psychology; D001590:Benztropine / Q000008:administration & dosage; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D005476:Fluphenazine / Q000008:administration & dosage / Q000031:analogs & derivatives; D005500:Follow-Up Studies; D006801:Humans; D007099:Imipramine / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000188:drug therapy* / Q000523:psychology; D012559:Schizophrenia / Q000188:drug therapy*; D012565:Schizophrenic Psychology
chemical_list: D001590:Benztropine; C011825:fluphenazine depot; D007099:Imipramine; D005476:Fluphenazine