[The "HELLP syndrome" without fragmentocytes: do drug-induced antibodies play a role?].
This is a case report on a nulliparous women, who developed the HELLP syndrome following intravenous tocolysis. Contrary to our expectations, neither schistocytes nor signs of intravasal coagulation were apparent; however, we found Fenoterol-associated anti-erythrocyte antibodies. However, the low titre of these antibodies does not explain the massive haemolysis. It is suggested, that these antibodies represent a causal factor in developing the HELLP syndrome.
Drack
G
G
Departement für Frauenheilkunde, Universitätsspital, Zürich.
Neftel
K
K
Lauper
U
U
Gmür
D
D
D000328:Adult; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D007231:Infant, Newborn; D008107:Liver Diseases / Q000150:complications* / Q000201:enzymology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology*; D013577:Syndrome; D013921:Thrombocytopenia / Q000150:complications*; D000637:Transaminases / Q000032:analysis
D000637:Transaminases
"HELLP-Syndrom" ohne Fragmentozyten: Spielen medikamenteninduzierte Antikörper eine Rolle?