title: Bioavailability of manganese from feed grade manganese oxides for broiler chicks.
abstract: An experiment was conducted to study the relative biological availability of Mn from inorganic Mn sources using 288, 1-day-old male Cobb feather-sexed chicks. Chicks were fed a basal corn-soybean meal diet (82.5 ppm Mn, as-fed basis) ad libitum or the basal diet supplemented with 0, 1,000, 2,000, or 3,000 ppm Mn from reagent grade (RG) MnSO4.H2O, MnO RG, or feed grade (FG) Oxide A, B, or C for 21 days. Bone and kidney Mn concentrations were used to estimate bioavailability. Manganese source and level had no effect on chick performance. Uptake of dietary Mn by bone and kidney from all sources was highly linear (P less than .001). Based on multiple linear regression slopes from bone Mn concentrations, the relative bioavailability values of MnO RG and MnO FG A, B, and C were 81.9 +/- 6.0, 93.1 +/- 6.7, 75.0 +/- 3.6, and 70.3 +/- 5.7, respectively, compared with 100% for MnSO4; those based on kidney Mn were 85.7 +/- 7.9, 68.0 +/- 7.5, 52.2 +/- 4.2, and 53.0 +/- 7.3, respectively.
authors.affiliation: Department of Animal Science, University of Florida, Gainesville 32611.
authors.forename: J
authors.initials: J
authors.lastname: Wong-Valle
authors.forename: C B
authors.initials: CB
authors.lastname: Ammerman
authors.forename: P R
authors.initials: PR
authors.lastname: Henry
authors.forename: P V
authors.initials: PV
authors.lastname: Rao
authors.forename: R D
authors.initials: RD
authors.lastname: Miles
mesh_terms: D000821:Animal Feed; D000818:Animals; D001682:Biological Availability; D001842:Bone and Bones / Q000032:analysis / Q000378:metabolism; D002645:Chickens / Q000378:metabolism*; D004435:Eating; D007668:Kidney / Q000032:analysis / Q000378:metabolism; D008297:Male; D008345:Manganese / Q000032:analysis / Q000493:pharmacokinetics*; D017895:Manganese Compounds; D010087:Oxides; D011897:Random Allocation; D012044:Regression Analysis; D013054:Spectrophotometry, Atomic; D015430:Weight Gain; D014961:X-Ray Diffraction
chemical_list: D017895:Manganese Compounds; D010087:Oxides; D008345:Manganese; C027424:manganese oxide