[The role of neurochemical mechanisms of the dorsal raphe nucleus in various models of anxiety states in rats].
Dopamine and serotonin microinjection in the dorsal raphe nucleus of rats does not influence the alarm state in the test of "threatening situation" avoidance, but increases or weakens the state of alarm in the rest of "illuminated site" avoidance. Local injection of GABA in this midbrain formation weakens the alarm state in the test of "threatening situation" avoidance but is not effective in the test of "illuminated site" avoidance. Chemical stimulation of the raphe nucleus by glutaminic acid does not influence the two different experimentally modelled states of alarm, but modulates the mechanisms controlling the instinct of darkness preference by rats.
Talalaenko
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D000818:Animals; D001007:Anxiety / Q000209:etiology / Q000503:physiopathology*; D001362:Avoidance Learning / Q000187:drug effects / Q000502:physiology; D003214:Conditioning, Classical / Q000187:drug effects / Q000502:physiology; D004195:Disease Models, Animal; D004298:Dopamine / Q000494:pharmacology; D004558:Electric Stimulation; D005971:Glutamates / Q000494:pharmacology; D018698:Glutamic Acid; D008297:Male; D008845:Microinjections; D018377:Neurotransmitter Agents / Q000502:physiology*; D010775:Photic Stimulation; D011903:Raphe Nuclei / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D012701:Serotonin / Q000494:pharmacology; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology
D005971:Glutamates; D018377:Neurotransmitter Agents; D012701:Serotonin; D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid; D004298:Dopamine
O roli neĭrokhimicheskikh mekhanizmov dorzal'nogo iadra shva v razlichnykh modeliakh trevozhnykh sostoianiĭ u krys.