title: [Plasma fibrinogen in female patients with genital cancer and its early stage].
abstract: Changes of plasma fibrinogen derivates in 54 female patients suffering from carcinomas of the genital system (36 with cervix carcinoma, 9 with ovarian carcinomas, 7 with carcinomas of the corpus uteri, 1 woman with a vulva and 1 patient with vaginal carcinoma) and 6 females with cervical intraepithelial neoplasia were investigated. It was shown, that the fibrinogen content and the concentration of soluble fibrin monomer complexes in blood plasma depend on the extension of the clinically diagnosed tumor. Furthermore, differently degraded fibrinogens were demonstrated to exist in the blood circulation. The extent of fibrinogenolysis did not correlate with the clinically diagnosed tumor stage.
authors.forename: R
authors.initials: R
authors.lastname: Lober
authors.forename: S
authors.initials: S
authors.lastname: Krantz
authors.forename: M
authors.initials: M
authors.lastname: Lober
mesh_terms: D000230:Adenocarcinoma / Q000097:blood; D000328:Adult; D000368:Aged; D002278:Carcinoma in Situ / Q000097:blood*; D002294:Carcinoma, Squamous Cell / Q000097:blood; D004715:Endometriosis / Q000097:blood; D005260:Female; D005340:Fibrinogen / Q000032:analysis*; D005833:Genital Neoplasms, Female / Q000097:blood*; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000097:blood; D002583:Uterine Cervical Neoplasms / Q000097:blood; D014594:Uterine Neoplasms / Q000097:blood; D014625:Vaginal Neoplasms / Q000097:blood; D014846:Vulvar Neoplasms / Q000097:blood
chemical_list: D005340:Fibrinogen
vernacular_title: Untersuchungen über das Plasmafibrinogen bei Patientinnen mit Karzinom des Genitalsystems und seine Vorstufen.