title: Prophylaxis of postoperative lumbar spondylodiscitis.
abstract: Spondylodiscitis after lumbar disc surgery is a well-known complication with a frequency of 0.1 to 3%. According to the authors, the etiological factors are: combination of operated segment instability, damage to the lower and upper plates due to disc space curettage and transmission of germs. After treatment of 100 selected cases, all with increased risk of postoperative spondylodiscitis, distinct possibilities for prevention have been discovered. Basic treatment consisted of 3 x 80 mg perioperative doses of Gentamicin i.m. In addition a collagen sponge (Sulmycin Implant) containing 50 mg Gentamycin was inserted in the cleared disc spaces of 50 patients. Complications in this procedure were not observed. The following is recommended for prevention of postoperative spondylodiscitis: a careful operating technique, perioperative antibiotics, and in particularly endangered patients, insertion of Sulmycin Implant in the disc-spaces.
authors.affiliation: Neurosurgical Clinic, Clinic Minden, Minden, West Germany.
authors.forename: P M
authors.initials: PM
authors.lastname: Zink
authors.forename: A M
authors.initials: AM
authors.lastname: Frank
authors.forename: A E
authors.initials: AE
authors.lastname: Trappe
mesh_terms: D000328:Adult; D000368:Aged; D015299:Discitis / Q000188:drug therapy / Q000517:prevention & control*; D004343:Drug Implants; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use*; D006801:Humans; D007403:Intervertebral Disc / Q000601:surgery; D008159:Lumbar Vertebrae / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy / Q000517:prevention & control*
chemical_list: D004343:Drug Implants; D005839:Gentamicins