Interaction between the serotonin and dopamine systems in humans: preliminary findings.
The availability of peripheral tools, such as platelet [3H]-imipramine binding and electroretinogram b-wave amplitude, for investigating serotonin and dopamine systems respectively, prompted us to explore the possible relationships between these two systems in a group of 8 healthy drug-free volunteers. The results showed a significant correlation between the peripheral parameters of serotonin and dopamine systems and underline the importance of studying different neurotransmitters at the same time in humans.
Castrogiovanni
P
P
Department of Psychiatry, University of Pisa, Italy.
Di Muro
A
A
Maremmani
I
I
Perossini
M
M
Marazziti
D
D
D000328:Adult; D001792:Blood Platelets / Q000378:metabolism*; D001921:Brain / Q000378:metabolism / Q000502:physiology*; D004298:Dopamine / Q000502:physiology*; D004596:Electroretinography; D005260:Female; D006801:Humans; D007099:Imipramine / Q000378:metabolism*; D008297:Male; D012160:Retina / Q000502:physiology*; D012701:Serotonin / Q000502:physiology*
D012701:Serotonin; D007099:Imipramine; D004298:Dopamine