title: [A model of the isolated blood perfused lung of rats in testing hypoxic pulmonary vasoconstriction].
abstract: Comparing two variants of models (in situ, ex situ) of the isolated blood-perfused rat lung for measurement of the hypoxic pulmonary vasoconstriction the in situ preparation gave better results. The optimal severity of hypoxia was 2% O2 in intervals (hypoxia and normoxia, respectively) of seven minutes. The model works sufficiently for two hours.
authors.affiliation: Forschungsinstitut für Lungenkrankheiten und Tbk Berlin/DDR.
authors.forename: R
authors.initials: R
authors.lastname: Brandt
authors.forename: A
authors.initials: A
authors.lastname: Oddoy
authors.forename: J
authors.initials: J
authors.lastname: Böhnke
authors.forename: W
authors.initials: W
authors.lastname: Schilling
mesh_terms: D000818:Animals; D000860:Hypoxia / Q000503:physiopathology*; D008955:Models, Cardiovascular; D009131:Muscle, Smooth, Vascular / Q000503:physiopathology*; D010477:Perfusion; D011651:Pulmonary Artery / Q000503:physiopathology; D011652:Pulmonary Circulation; D011669:Pulmonary Wedge Pressure; D051381:Rats; D014661:Vasoconstriction
vernacular_title: Das Modell der isolierten blutperfundierten Lunge von Ratten zur Testung der hypoxischen pulmonalen Vasokonstriktion.