title: Population studies in northern Sweden. XVI. GC subtypes.
abstract: The frequencies of group-specific component (GC) subtypes were studied in a population of 4,053 conscripts and blood donors from the counties of Västerbotten and Norrbotten in northern Sweden. The individuals were distributed according to place of birth into 23 subpopulations. A significant heterogeneity between the 23 regions was observed for the GC*1F, GC*1S and GC*2 genes, and clines were found for all genes. The frequency of the GC*1F gene was increasing in the northern direction, and the frequencies of the GS*1S and GC*2 genes were increasing in the southern direction. The geographical pattern of the GC*1F gene frequency could be explained in terms of Lappish influence.
authors.affiliation: Department of Medical Genetics, University of Umeå, Sweden.
authors.forename: P O
authors.initials: PO
authors.lastname: Nylander
authors.forename: L
authors.initials: L
authors.lastname: Beckman
mesh_terms: D005006:Ethnicity; D005787:Gene Frequency / Q000235:genetics*; D005828:Genetics, Population; D006801:Humans; D011110:Polymorphism, Genetic / Q000235:genetics; D013548:Sweden; D014809:Vitamin D-Binding Protein / Q000145:classification / Q000235:genetics*
chemical_list: D014809:Vitamin D-Binding Protein