Heparin cofactor II activity in plasma during pregnancy and oral contraceptive use.
Inhibition of thrombin by heparin is mediated by at least two plasma proteins, antithrombin III, and heparin cofactor II. The plasma titer of heparin cofactor II was significantly elevated in both pregnant women and users of oral contraceptives.
Massouh
M
M
Department of Medicine, University Hospital of Cleveland, OH 44106.
Jatoi
A
A
Gordon
E M
EM
Ratnoff
O D
OD
D000328:Adult; D003276:Contraceptives, Oral / Q000008:administration & dosage / Q000378:metabolism*; D005260:Female; D015844:Heparin Cofactor II / Q000032:analysis*; D006801:Humans; D011247:Pregnancy / Q000097:blood*
D003276:Contraceptives, Oral; D015844:Heparin Cofactor II