title: Per rectal thallium scintigraphy for the assessment of portosystemic shunt: an experimental study in the bile duct ligated rats.
abstract: Bile duct ligated rats (n = 7) have been investigated for 6 months. Two patterns of evolution have been observed: (i) progressive development of cirrhosis and portosystemic shunt (detected by 201Tl per rectal scintigraphy) in three animals, (ii) repermeabilization of the biliary tract in four animals. Despite the small number of animals investigated, the 201Tl per rectal scintigraphy seems to be a good indicator of portosystemic shunt secondary to biliary cirrhosis.
authors.affiliation: Department of Pediatrics, Hôpitaux Saint-Pierre et Brugmann, Free University of Brussels, Belgium.
authors.forename: L
authors.initials: L
authors.lastname: Van Maldergem
authors.forename: O
authors.initials: O
authors.lastname: Jeghers
authors.forename: G
authors.initials: G
authors.lastname: Cadiere
authors.forename: C
authors.initials: C
authors.lastname: de Prez
authors.forename: H R
authors.initials: HR
authors.lastname: Ham
authors.forename: A
authors.initials: A
authors.lastname: Piepsz
mesh_terms: D000285:Administration, Rectal; D000818:Animals; D002779:Cholestasis / Q000000981:diagnostic imaging*; D003097:Collateral Circulation; D004195:Disease Models, Animal; D007098:Imino Acids / Q000008:administration & dosage; D008103:Liver Cirrhosis / Q000000981:diagnostic imaging / Q000209:etiology; D015609:Organotechnetium Compounds / Q000008:administration & dosage; D011169:Portal Vein / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D051381:Rats; D011919:Rats, Inbred Strains; D019780:Technetium Tc 99m Lidofenin; D013793:Thallium / Q000008:administration & dosage; D013794:Thallium Radioisotopes / Q000008:administration & dosage; D014684:Venae Cavae / Q000000981:diagnostic imaging*
chemical_list: D007098:Imino Acids; D015609:Organotechnetium Compounds; D013794:Thallium Radioisotopes; C027549:thallium chloride; D019780:Technetium Tc 99m Lidofenin; D013793:Thallium