title: Proteinuria, glomerulomegaly and focal glomerulosclerosis in a grossly obese man with obstructive sleep apnea syndrome.
abstract: A grossly obese (149 kg) man with the sleep apnea syndrome was found to have proteinuria and a supernormal glomerular filtration rate. Renal histology showed glomerulomegaly and focal glomerulosclerosis. It is suggested that obesity may induce glomerular hyperfiltration and in turn glomerulosclerosis.
authors.affiliation: Department of Nephrology, Christchurch Hospital, New Zealand.
authors.forename: R R
authors.initials: RR
authors.lastname: Bailey
authors.forename: K L
authors.initials: KL
authors.lastname: Lynn
authors.forename: A F
authors.initials: AF
authors.lastname: Burry
authors.forename: C
authors.initials: C
authors.lastname: Drennan
mesh_terms: D000328:Adult; D005919:Glomerular Filtration Rate; D005921:Glomerulonephritis; D005923:Glomerulosclerosis, Focal Segmental / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology / Q000503:physiopathology; D008297:Male; D009767:Obesity, Morbid / Q000150:complications* / Q000503:physiopathology; D011507:Proteinuria / Q000150:complications* / Q000503:physiopathology; D012891:Sleep Apnea Syndromes / Q000150:complications* / Q000503:physiopathology