The difference between human C3F and C3S results from a single amino acid change from an asparagine to an aspartate residue at position 1216 on the alpha chain of the complement component, C3.
Poznansky
M C
MC
Clissold
P M
PM
Lachmann
P J
PJ
D001216:Asparagine / Q000235:genetics*; D001224:Aspartic Acid / Q000235:genetics*; D001483:Base Sequence; D003176:Complement C3 / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data
D003176:Complement C3; D001224:Aspartic Acid; D001216:Asparagine