[Gastro-esophageal reflux and asthma. Clinical experience].
Gastroesophageal reflux (GER) may contribute to the persistence of asthma and may be triggered and/or exacerbated by treatment with bronchodilatory and cortisone drugs. For this reason, GER should be suspected in patients with asthma non-responsive to treatment. In fact in this series 24 hour pH monitoring revealed GER in 7 out of 9 (77%) patients with persistent asthma. The use of a personally developed diagnostic protocol permitted the identification of various situations in 4 patients who completed the study: one coincidental association, one GER caused by theophylline and constituting the main cause of the bronchial obstruction.
Barberio
G
G
Ruggeri
C
C
Pajno
G B
GB
Morabito
L
L
Pollicino
A
A
Di Pasquale
F
F
Terranova
M L
ML
D001249:Asthma / Q000188:drug therapy / Q000209:etiology*; D002648:Child; D002985:Clinical Protocols; D005260:Female; D005764:Gastroesophageal Reflux / Q000139:chemically induced / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D013806:Theophylline / Q000009:adverse effects / Q000627:therapeutic use
D013806:Theophylline
Reflusso gastro-esofageo ed asma. Esperienza clinica.