title: Aldehyde dehydrogenase and monoamine oxidase in rat liver mitochondria.
abstract: Monoamine oxidase (EC 1.4.3.4) and aldehyde dehydrogenase (EC 1.2.1.3) activities were compared in the liver mitochondria of male and female rats. Monoamine oxidase activity using benzylamine as a substrate was significantly higher in males as compared with females: 1.45 versus 0.74 mumols/mg mitochondrial protein/hr, respectively. Monoamine oxidase activity using tyramine as a substrate and aldehyde dehydrogenase activity were the same in males and females. Monoamine oxidase-tyramine and aldehyde dehydrogenase activities did not vary with the different phases of the estrous cycle in the female but the activity of monoamine oxidase-benzylamine did; rats in the proestrous phase had the highest activity and those in the estrous phase had the lowest.
authors.affiliation: Center of Alcohol Studies, Rutgers University, Piscataway, NJ 08855-0969.
authors.forename: S C
authors.initials: SC
authors.lastname: Turan
authors.forename: P C
authors.initials: PC
authors.lastname: Shah
authors.forename: R
authors.initials: R
authors.lastname: Pietruszko
mesh_terms: D000444:Aldehyde Dehydrogenase / Q000378:metabolism*; D000818:Animals; D004971:Estrus / Q000378:metabolism; D005260:Female; D008297:Male; D008930:Mitochondria, Liver / Q000201:enzymology*; D008995:Monoamine Oxidase / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D000444:Aldehyde Dehydrogenase; D008995:Monoamine Oxidase