title: Laboratory evaluation of a double lumen catheter for venovenous neonatal ECMO.
abstract: The authors designed and tested a 14F outside diameter thin-walled double lumen catheter (DLC) for neonatal venovenous (VV) extracorporeal membrane oxygenation (ECMO). In vitro tests with water and dye solution showed capacity of the drainage lumen was 1,096 ml/min at 100 cm siphon, and pressure drop across the perfusion lumen was 300 mmHg at 500 ml/min flow. Recirculation at 500 ml/min flow ranged from 5 to 29%, depending upon simulated cardiac output. The highest serum hemoglobin during 12 hour 400 ml/min flow VV bypass in five dogs was 49 mg/dl. Typical oxygen transport in four dogs was 25 cc/min at 400 ml/min flow. This catheter is well suited for clinical VV ECMO in neonates.
authors.affiliation: University of Michigan Medical School, Department of Surgery, Ann Arbor.
authors.forename: T
authors.initials: T
authors.lastname: Otsu
authors.forename: S I
authors.initials: SI
authors.lastname: Merz
authors.forename: K A
authors.initials: KA
authors.lastname: Hultquist
authors.forename: R J
authors.initials: RJ
authors.lastname: Attorri
authors.forename: H L
authors.initials: HL
authors.lastname: Anderson
authors.forename: D E
authors.initials: DE
authors.lastname: Scheffler
authors.forename: A
authors.initials: A
authors.lastname: Ahmad
authors.forename: R H
authors.initials: RH
authors.lastname: Bartlett
mesh_terms: D001783:Blood Flow Velocity; D002408:Catheters, Indwelling; D006801:Humans; D007231:Infant, Newborn; D007601:Jugular Veins; D008955:Models, Cardiovascular; D010100:Oxygen / Q000097:blood; D010107:Oxygenators, Membrane; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*; D014683:Vena Cava, Superior
chemical_list: D010100:Oxygen