title: Hepatocellular lipofuscin in pre-eclampsia.
abstract: Thirty liver specimens from 30 pre-eclamptic women with and without liver dysfunction were examined for the amount of lipofuscin pigment deposited. The amount of hepatic lipofuscin correlated positively with plasma urate concentrations. This finding may indicate an involvement of oxygen-free radicals and xanthine oxidase in the pathophysiology of pre-eclampsia.
authors.forename: H
authors.initials: H
authors.lastname: Minakami
authors.forename: K
authors.initials: K
authors.lastname: Kimura
authors.forename: T
authors.initials: T
authors.lastname: Tamada
authors.forename: Y
authors.initials: Y
authors.lastname: Yasuda
authors.forename: N
authors.initials: N
authors.lastname: Hirota
mesh_terms: D005260:Female; D005609:Free Radicals; D006801:Humans; D008062:Lipofuscin / Q000032:analysis*; D008099:Liver / Q000032:analysis* / Q000166:cytology / Q000473:pathology; D010100:Oxygen / Q000378:metabolism*; D010860:Pigments, Biological / Q000032:analysis*; D011225:Pre-Eclampsia / Q000378:metabolism* / Q000503:physiopathology; D011247:Pregnancy; D014527:Uric Acid / Q000097:blood
chemical_list: D005609:Free Radicals; D008062:Lipofuscin; D010860:Pigments, Biological; D014527:Uric Acid; D010100:Oxygen