Localization of fructose 6-P,2-kinase: fructose 2,6-bisphosphatase to human chromosome X.
The gene encoding human liver fructose 6-P,2-kinase: fructose 2,6-bisphosphatase has been assigned to human chromosome X by Southern analysis of a panel of human-rodent somatic cell hybrid DNAs with a cDNA for this gene. A simple two-allele restriction fragment length polymorphism was found with the Fru-6-P,2-kinase:Fru-2,6-bisphosphatase probe; this will allow further localization of this gene by genetic linkage analysis.
Olson
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S
Laboratory of Biochemistry, National Cancer Institute, Bethesda, Maryland.
Uyeda
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McBride
O W
OW
D000818:Animals; D015139:Blotting, Southern; D002874:Chromosome Mapping; D002883:Chromosomes, Human, Pair 14; D015342:DNA Probes; D005260:Female; D006801:Humans; D006822:Hybrid Cells; D008099:Liver / Q000201:enzymology; D008297:Male; D009097:Multienzyme Complexes / Q000235:genetics*; D025481:Phosphofructokinase-2; D010744:Phosphoric Monoester Hydrolases / Q000235:genetics*; D010770:Phosphotransferases / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length; D014178:Translocation, Genetic; D014960:X Chromosome
D015342:DNA Probes; D009097:Multienzyme Complexes; D010770:Phosphotransferases; D025481:Phosphofructokinase-2; D010744:Phosphoric Monoester Hydrolases