title: Characterization of eight VNTR loci by agarose gel electrophoresis.
abstract: Allelic frequencies and their confidence intervals were obtained for eight independent VNTR loci from a sample of more than 75 Utah Caucasians. Using high-resolution agarose gel electrophoresis, we were able to resolve alleles at the D17S5 locus that differed by only one repeating unit; it was therefore possible to name the alleles according to the number of repeating units each contained. Two a priori probabilities were calculated for each VNTR locus separately and for all eight loci jointly: (i) the "power of exclusion" for an alleged father/mother/child trio and for an alleged parent/child duo, and (ii) the "probability of matching" when two unrelated individuals or two siblings are genotyped.
authors.affiliation: Department of Human Genetics, University of Utah Medical Center, Salt Lake City, 84132.
authors.forename: S J
authors.initials: SJ
authors.lastname: Odelberg
authors.forename: R
authors.initials: R
authors.lastname: Plaetke
authors.forename: J R
authors.initials: JR
authors.lastname: Eldridge
authors.forename: L
authors.initials: L
authors.lastname: Ballard
authors.forename: P
authors.initials: P
authors.lastname: O'Connell
authors.forename: Y
authors.initials: Y
authors.lastname: Nakamura
authors.forename: M
authors.initials: M
authors.lastname: Leppert
authors.forename: J M
authors.initials: JM
authors.lastname: Lalouel
authors.forename: R
authors.initials: R
authors.lastname: White
mesh_terms: D000483:Alleles; D004587:Electrophoresis, Agar Gel; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D012150:Polymorphism, Restriction Fragment Length; D011336:Probability; D012091:Repetitive Sequences, Nucleic Acid