[Experiments on the production of monoclonal antibodies against lymphocyte antigens in cattle with enzootic cattle leukosis].
Hybridomas were produced which secrete antibodies against cell surface antigens of neoplastic bovine lymphocytes. The monoclonal antibodies of three hybridomas react only with leukemic cells but not with other tested cellular and soluble antigens. Four hybridomas secrete antibodies which probably recognize virus-encoded structures on outer membranes of leukemic cells.
Behn
I
I
Engelke
U
U
D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis*; D000951:Antigens, Neoplasm / Q000276:immunology; D000954:Antigens, Surface / Q000276:immunology*; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology*; D000939:Epitopes; D006825:Hybridomas; D007938:Leukemia / Q000662:veterinary*; D008214:Lymphocytes / Q000276:immunology*
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D000954:Antigens, Surface; D000939:Epitopes
Experimente zur Herstellung monoklonaler Antikörper gegen Lymphozytenantigene von Rindern mit enzootischer Rinderleukose.