title: Proliferation of primordial germ cells of frogs stimulated by a fraction of granules derived from Rana nigromaculata embryos at the tail-bud stage.
abstract: A fraction of heavy granules, obtained from embryos of the frog (Rana nigromaculata) at the tail-bud stage by centrifugation at 1700 x g, were shown to stimulate the formation of proliferation of the primordial germ cells not only of the same species but also of a closely related species.
authors.affiliation: Faculty of Integrated Arts and Sciences, Hiroshima University, Japan
authors.forename: T
authors.initials: T
authors.lastname: Shirane
mesh_terms: D000818:Animals; D002455:Cell Division; D003594:Cytoplasmic Granules / Q000502:physiology*; D004625:Embryo, Nonmammalian / Q000502:physiology* / Q000648:ultrastructure; D005854:Germ Cells / Q000166:cytology*; D011898:Ranidae