title: A time-course study on effects of aluminium on mitotic cell division in Allium sativum.
abstract: Cytotoxic effects of aluminium sulphate on root-tip cells of Allium sativum during a time-course study and during recovery were observed. The endpoints considered were mitotic index and frequencies of aberrant cells and micronuclei induced. Chronic exposure induced mitotic depression and abnormal cells to a degree directly proportional to the concentration used and the period of treatment up to 24 h. A reduction of the early higher level of toxicity was noticed following 48 h of treatment and subsequent recovery in aluminium-free nutrient media in experiments carried out with lower concentrations.
authors.affiliation: Department of Botany, University of Calcutta, India.
authors.forename: A K
authors.initials: AK
authors.lastname: Roy
authors.forename: A
authors.initials: A
authors.lastname: Sharma
authors.forename: G
authors.initials: G
authors.lastname: Talukder
mesh_terms: D000490:Allium; D000535:Aluminum / Q000494:pharmacology*; D002869:Chromosome Aberrations; D004305:Dose-Response Relationship, Drug; D015162:Micronucleus Tests; D008938:Mitosis / Q000187:drug effects*; D008940:Mitotic Index; D013997:Time Factors
chemical_list: D000535:Aluminum