Cortical hyperostosis: a complication of prostaglandin E1 treatment in congenital heart disease.
Prostaglandin E1 (PGE1) is an essential drug for infants with ductal-dependent congenital heart disease. Cortical hyperostosis of the long bones is one of the complications during and after PGE1 therapy and should be considered in the differential diagnosis of periostitis in the infant.
Smet
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Marchal
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Lambert
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Devlieger
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Gewillig
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D000527:Alprostadil / Q000009:adverse effects* / Q000627:therapeutic use; D006330:Heart Defects, Congenital / Q000188:drug therapy; D006801:Humans; D015576:Hyperostosis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D007231:Infant, Newborn; D008297:Male; D010521:Periosteum / Q000187:drug effects; D011664:Pulmonary Valve / Q000002:abnormalities*; D011859:Radiography
D000527:Alprostadil