title: Dynorphin-containing pilomotor neurons in the superior cervical ganglion of guinea pigs.
abstract: Retrograde axonal tracing and double-labelling immunofluorescence have been combined to determine the neuropeptide content of identified pilomotor neurons in the superior cervical ganglion of guinea pigs. These neurons lacked immunoreactivity to neuropeptide Y (NPY) but they generally contained low levels of immunoreactivity to prodynorphin-derived peptides, including dynorphin A(1-8), dynorphin A(1-17), and alpha-neo-endorphin. Thus pilomotor neurons are neurochemically distinct from superior cervical ganglion cells which contain immunoreactivity to NPY and prodynorphin-derived peptides and which innervate the iris and most of the vasculature in the head of guinea pigs. They are also distinct from sympathetic secretomotor neurons which lack both NPY and prodynorphin-derived peptides.
authors.affiliation: Department of Anatomy and Histology, School of Medicine, Flinders University of South Australia, Bedford Park.
authors.forename: I L
authors.initials: IL
authors.lastname: Gibbins
mesh_terms: D000818:Animals; D004399:Dynorphins / Q000378:metabolism*; D005260:Female; D005728:Ganglia, Sympathetic / Q000166:cytology / Q000378:metabolism*; D006168:Guinea Pigs; D007150:Immunohistochemistry; D008297:Male; D009132:Muscles / Q000294:innervation*; D009478:Neuropeptide Y / Q000378:metabolism; D010863:Piloerection; D012018:Reflex; D012867:Skin / Q000294:innervation*; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism
chemical_list: D009478:Neuropeptide Y; D004399:Dynorphins; D014446:Tyrosine 3-Monooxygenase