title: Linkage between alpha 1B-glycoprotein (A1BG) and Lutheran (LU) red blood group system: assignment to chromosome 19: new genetic variants of A1BG.
abstract: alpha 1B-glycoprotein (A1BG) polymorphism was examined in a Danish family material (no. 604-1505) with particular regard to markers on chromosome 19. For A1BG-LU we found a lod score z = 3.06 at theta = 0.05 in males, and z = 1.42 at theta = 0.10 in females, which assigns A1BG to chromosome 19. Close linkage to C3, SE, PEPD, APOC2, D19S7, D19S8 and D19S9 was excluded. The most likely order would appear to be C3-SE-LU-A1BG.
authors.affiliation: University Institute of Medical Genetics, Copenhagen, Denmark.
authors.forename: H
authors.initials: H
authors.lastname: Eiberg
authors.forename: M L
authors.initials: ML
authors.lastname: Bisgaard
authors.forename: J
authors.initials: J
authors.lastname: Mohr
mesh_terms: D000483:Alleles; D001798:Blood Proteins / Q000235:genetics*; D002888:Chromosomes, Human, Pair 19; D005260:Female; D005787:Gene Frequency / Q000235:genetics; D008040:Genetic Linkage; D014644:Genetic Variation / Q000235:genetics; D006023:Glycoproteins; D006801:Humans; D007136:Immunoglobulins; D008126:Lod Score; D008188:Lutheran Blood-Group System / Q000235:genetics*; D008297:Male
chemical_list: C048566:A1BG protein, human; D001798:Blood Proteins; D006023:Glycoproteins; D007136:Immunoglobulins; D008188:Lutheran Blood-Group System