[Changes in the immunotropic activity of neutrophilokins in the course of experimental staphylococcal infection].
The influence of the products secreted by activated neutrophils (neutrophilokins) of mice, both intact and infected with staphylococci, on the activity of mouse spleen cells in the graft-versus-host reaction, immune response to sheep red blood cells and the antigen-presenting function of peritoneal macrophages was studied. Neutrophilokins of intact mice stimulated the activity of immunocompetent cells. Neutrophilokins obtained from infected mice on day 3 after infection produced an immunosuppressing effect. On day 7 after infection the immunostimulating activity of neutrophils was restored and showed practically no difference from the normal level.
Vlasov
A V
AV
Zurochka
A V
AV
Dolgushin
I I
II
D000818:Animals; D000921:Antibody-Producing Cells / Q000276:immunology; D001202:Ascitic Fluid / Q000166:cytology / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology; D007114:Immunization; D008222:Lymphokines / Q000276:immunology* / Q000378:metabolism; D051379:Mice; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009504:Neutrophils / Q000276:immunology* / Q000637:transplantation; D013154:Spleen / Q000276:immunology; D013203:Staphylococcal Infections / Q000276:immunology*; D013997:Time Factors
D008222:Lymphokines
Izmenenie immunotropnoĭ aktivnosti neĭtrofilokinov v techenie éksperimental'noĭ stafilokokkovoĭ infektsii.