title: Early neurohistopathological changes of canine lumbosacral spinal cord segments in ischemia-reperfusion-induced paraplegia.
abstract: Mapping the canine lumbosacral spinal cord neurons damaged by ischemia-reperfusion after high thoracic aorta ligation was performed using the Nauta degenerating method. Highly Nauta-positive perikarya of the long ascending projection systems in the 4th to 6th dorsal layer, interneurons in the 7th layer and motoneurons in the 8th and 9th layers in L3-S3 segments subjected to 30 min of ischemia and 30 min of reperfusion were localized and their laminar distribution was specified. Spastic paraplegia fully developed 2 days postoperatively after 30 min of aortic ligation is neurohistopathologically characterized by occurrence of enlarged Nauta-positive boutons with prevailing localization in the 4th to 8th layer of the gray matter.
authors.affiliation: Institute of Neurobiology, Centre of Physiological Sciences, Slovak Academy of Sciences, Kosice, Czechoslovakia.
authors.forename: J
authors.initials: J
authors.lastname: Marsala
authors.forename: I
authors.initials: I
authors.lastname: Sulla
authors.forename: M
authors.initials: M
authors.lastname: Santa
authors.forename: M
authors.initials: M
authors.lastname: Marsala
authors.forename: E
authors.initials: E
authors.lastname: Mechírová
authors.forename: P
authors.initials: P
authors.lastname: Jalc
mesh_terms: D000818:Animals; D004285:Dogs; D005260:Female; D008297:Male; D015427:Reperfusion Injury / Q000473:pathology*; D013116:Spinal Cord / Q000473:pathology*; D013997:Time Factors