title: Prediction of the conformation and antigenic determinants of the V-sis viral oncogene product homologous with human platelet-derived growth factor.
abstract: In an extensive study involving unification of secondary structure prediction methods to predict peptide backbone angles, folding simulations, and interactive graphics we have calculated conformations for a 160 residue p28sis protein fragment. We demonstrate that the state of the art is sufficient to aid artificial vaccine design.
authors.forename: B
authors.initials: B
authors.lastname: Robson
authors.forename: E
authors.initials: E
authors.lastname: Platt
authors.forename: P W
authors.initials: PW
authors.lastname: Finn
authors.forename: P
authors.initials: P
authors.lastname: Millard
authors.forename: J F
authors.initials: JF
authors.lastname: Gibrat
authors.forename: J
authors.initials: J
authors.lastname: Garnier
mesh_terms: D000956:Antigens, Viral; D003201:Computers; D000939:Epitopes; D005814:Genes, Viral; D006801:Humans; D008958:Models, Molecular; D020575:Oncogene Proteins v-sis; D009857:Oncogenes; D010982:Platelet-Derived Growth Factor / Q000235:genetics*; D011487:Protein Conformation; D012842:Sarcoma Virus, Woolly Monkey / Q000235:genetics; D014764:Viral Proteins / Q000276:immunology*
chemical_list: D000956:Antigens, Viral; D000939:Epitopes; D020575:Oncogene Proteins v-sis; D010982:Platelet-Derived Growth Factor; D014764:Viral Proteins