title: [Gas-chromatographic analysis of hypercholestanol in the bile and its role in the pathogenesis of cholelithiasis].
abstract: The cholestanol/cholesterol ratio in the bladder and liver bile was estimated by capillary gas-liquid chromatography in patients with dyskinesia of the gallbladder, chronic acalculous cholecystitis, and chronic calculous cholecystitis. Cholesterol biliary calculi and their surface and intermediate layers and the core were examined either. The authors came to a conclusion that cholestanol/cholesterol ratio in the bladder and liver bile reflected the progress of liver cholesterol metabolism starting from the early stages of cholelithiasis to the formation of cholesterol biliary calculi. Therefore hypercholestanolcholia should be considered as an indicator of the risk of cholesterol biliary calculi development.
authors.forename: M I
authors.initials: MI
authors.lastname: Krikshtopaĭtis
authors.forename: S P
authors.initials: SP
authors.lastname: Chupin
authors.forename: Ia L
authors.initials: IaL
authors.lastname: Tiuriumin
authors.forename: S B
authors.initials: SB
authors.lastname: Nikiforov
authors.forename: L S
authors.initials: LS
authors.lastname: Fedorova
authors.forename: V L
authors.initials: VL
authors.lastname: Salenko
authors.forename: A I
authors.initials: AI
authors.lastname: Vialkov
mesh_terms: D001646:Bile / Q000032:analysis / Q000378:metabolism*; D055598:Chemical Phenomena; D002621:Chemistry; D002769:Cholelithiasis / Q000032:analysis / Q000209:etiology* / Q000378:metabolism; D002777:Cholestanols / Q000032:analysis / Q000378:metabolism*; D002784:Cholesterol / Q000032:analysis / Q000378:metabolism; D002849:Chromatography, Gas / Q000379:methods; D006801:Humans
chemical_list: D002777:Cholestanols; D002784:Cholesterol
vernacular_title: Gazozhidkostno-khromatograficheskoe opredelenie giperkholestanol- kholii i ee znacheniev patogeneze kholelitiaza.