[Quantification of pulmonary to systemic flow ratio (Qp/Qs) in children with patent ductus arteriosus by echocardiography].
The assessment of left-right ductal shunting flow in 35 children with PDA by 2-DCE with 35 normal children as a control was shown in the study. A close relationship was demonstrated between the grade of the diastolic negative contrast at the distal ends of the pulmonary artery and Q p/Qs. The diastolic negative contrast effect of 2-DCE could be used as a new important index in the assessment of left-to-right ductal shunting flow. Four parameters which were closely correlated with Qp/Qs were selected from 8 parameters by the stepwise multilinear regression procedure. The 4 parameters were grade II DNCE, LVPWER, grade I DNCE, LADR. A regression equation which was capable of assessing Q p/Qs noninvasively in children with PDA was derived from the 4 parameters. The accuracy of calculation of Qp/Qs by the regression equation was 80%.
Zhang
Y O
YO
Tang
S C
SC
Jin
Z G
ZG
Zhu
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Q
D000293:Adolescent; D001775:Blood Circulation; D002648:Child; D002675:Child, Preschool; D004374:Ductus Arteriosus, Patent / Q000503:physiopathology*; D004452:Echocardiography; D005260:Female; D006801:Humans; D008297:Male; D011652:Pulmonary Circulation