title: An automatic algorithm for immunoassay curve calibration using controlled quadratic splines.
abstract: An algorithm is described for the calibration of immunoassay curves. It employs a quadratic spline as the approximating function. The number and positions of the knots of the spline are chosen adaptively. The behaviour of the spline is controlled so that it preserves the key properties of the underlying function.
authors.affiliation: National Physical Laboratory, Teddington, UK.
authors.forename: H M
authors.initials: HM
authors.lastname: Anthony
authors.forename: M G
authors.initials: MG
authors.lastname: Cox
mesh_terms: D000465:Algorithms; D007118:Immunoassay; D008433:Mathematics; D008962:Models, Theoretical; D011506:Proteins / Q000032:analysis*
chemical_list: D011506:Proteins