title: Peripapillary (pericentral) pigmentary retinal degeneration.
abstract: Three patients with peripapillary (pericentral) pigmentary retinal degeneration described in 1978 were examined over a follow-up period of nine to 13 years. There was no extension of the geographic pigmentary abnormalities. The affected areas worsened as evidenced by an increase in pigment abnormalities, focal choroidal atrophy as seen on fluorescein angiography, and a diminution of the electroretinographic responses. One patient had increasing disabling symptoms of nyctalopia and poor peripheral and central vision, whereas the other two patients remained asymptomatic with excellent central vision.
authors.affiliation: Department of Ophthalmology, New York University Medical Center, NY 10016.
authors.forename: K G
authors.initials: KG
authors.lastname: Noble
mesh_terms: D004596:Electroretinography; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D008875:Middle Aged; D010775:Photic Stimulation; D012160:Retina / Q000503:physiopathology; D012162:Retinal Degeneration / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology*; D012168:Retinal Pigments / Q000378:metabolism; D014792:Visual Acuity
chemical_list: D012168:Retinal Pigments