title: Renal sympathetic nerve activity and plasma catecholamines during eating in cats.
abstract: We measured renal sympathetic nerve activity (RNA) and arterial plasma concentration of norepinephrine (NE) and epinephrine (EPI) before, during, and after eating in six conscious cats. Eating continued for a period of 5 min. RNA, heart rate (HR), and arterial blood pressure (AP) increased almost simultaneously with the onset of eating and reached a maximum value of 192%, 221 beats/min, and 121 mmHg at 2.5-5 min after the onset of eating, respectively. The plasma NE level increased significantly (P less than 0.05) during eating from the control value of 0.56 ng/ml and reached a maximum value of 1.33 ng/ml at 4.5-5 min, whereas the plasma EPI level did not change significantly from the control value of 0.12 ng/ml. The plasma levels of NE and EPI were unaffected by the blood samplings. The relationship between the changes in RNA and the plasma NE level during eating had a significant (P less than 0.05) positive correlation (r = 0.52). The result suggests that plasma NE concentration tends to increase with the rise in RNA during eating.
authors.affiliation: Department of Cardiac Physiology, National Cardiovascular Center, Research Institute, Osaka, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Matsukawa
authors.forename: T
authors.initials: T
authors.lastname: Honda
authors.forename: I
authors.initials: I
authors.lastname: Ninomiya
mesh_terms: D000818:Animals; D001794:Blood Pressure; D001800:Blood Specimen Collection; D002415:Cats; D004435:Eating / Q000502:physiology*; D004837:Epinephrine / Q000097:blood*; D006339:Heart Rate; D007668:Kidney / Q000294:innervation*; D009638:Norepinephrine / Q000097:blood*; D009994:Osmolar Concentration; D013564:Sympathetic Nervous System / Q000502:physiology*
chemical_list: D009638:Norepinephrine; D004837:Epinephrine