[Cluster analysis of 109 patients with systemic lupus erythematosus].
Using a grouping method we studied the disease homogeneity within a group of 109 patients with systemic lupus erythematosus. The mean observation period was 6 years and 8 months. By using a cluster analysis, the total group of patients could be subdivided into two subgroups which differed clearly in their symptomatology. One subgroup (n = 42) showed higher incidence of elevated serum creatinine values, proteinuria, oral ulceration and severe anaemia. All 13 deaths occurred in this group. The second group (n = 67) was characterized by a more benign course of disease, a notably decreased incidence of renal involvement, and the Raynaud's Phenomenon was comparatively frequent.
Bokemeyer
B
B
Thiele
K G
KG
D000328:Adult; D000740:Anemia / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis*; D009059:Mouth Diseases / Q000209:etiology; D011507:Proteinuria / Q000209:etiology; D011928:Raynaud Disease / Q000209:etiology; D013029:Space-Time Clustering; D014456:Ulcer / Q000209:etiology; D005719:gamma-Globulins / Q000378:metabolism
D005719:gamma-Globulins
Cluster-Analyse bei 109 Patienten mit systemischem Lupus erythematodes.