title: Effects of recombinant DNA-derived somatotropin and dietary energy intake on development of beef heifers: I. Growth and puberty.
abstract: The effects of dietary energy intake and somatotropin (STH) on growth and puberty were studied in 40 Angus heifers. At an average age of 7 mo (208 +/- 8 d), heifers were assigned to four treatment groups: 1) vehicle (V) + high energy (HE; 2.68 Mcal ME/kg DM), 2) recombinant DNA-derived STH (20.6 mg/d; s.c.) + HE, 3) V + low energy (LE; 2.22 Mcal ME/kg DM) or 4) STH + LE. Animals remained on treatments until 15.5 mo of age. Body weights (BW), hip heights (HH) and areas of pelvic openings (PA) were measured every 28 d and backfat thicknesses (BF) were measured every 56 d. Plasma progesterone was measured in blood samples taken three times per week beginning at 9 mo of age to determine age at first ovulation. Heifers fed HE were heavier (P less than .01), gained faster (P less than .01) and had greater BF (P less than .01) than those fed LE. Animals treated with STH gained faster (P less than .01) and were heavier (P less than .05) between 12 and 15 mo of age than V-treated heifers. Heifers treated with STH also had less BF (P less than .05) and a tendency for a greater (P = .08) increase in HH than in V-treated heifers. Somatotropin interacted with energy (P less than .05) and age (P less than .01) to influence PA. Somatotropin increased (P less than .01) PA in heifers fed the HE diet but not in those fed the LE diet.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: University of Kentucky, Lexington 40546-0215.
authors.forename: T M
authors.initials: TM
authors.lastname: McShane
authors.forename: K K
authors.initials: KK
authors.lastname: Schillo
authors.forename: J A
authors.initials: JA
authors.lastname: Boling
authors.forename: N W
authors.initials: NW
authors.lastname: Bradley
authors.forename: J B
authors.initials: JB
authors.lastname: Hall
mesh_terms: D000704:Analysis of Variance; D000821:Animal Feed; D000818:Animals; D001846:Bone Development / Q000187:drug effects; D002417:Cattle / Q000254:growth & development* / Q000502:physiology; D004032:Diet; D004435:Eating; D004734:Energy Metabolism; D005260:Female; D013006:Growth Hormone / Q000494:pharmacology*; D011994:Recombinant Proteins / Q000494:pharmacology; D012741:Sexual Maturation / Q000187:drug effects*; D015430:Weight Gain / Q000187:drug effects*
chemical_list: D011994:Recombinant Proteins; D013006:Growth Hormone