[UV-induced formation of DNA-protein cross-links in chromatin in the presence of chemical agents].
Hindered phenols, quinones, and SH-compounds have been studied as possible protectors and sensitizers of DNA-protein cross-linking in chromatin. Efficacy of cross-linking was estimated by the quantity of protein linked to DNA after UV irradiation at 254 um in the presence of chemical agents. Phenols and quinones exert protective influence on cross-linking whereas DNA-protein cross-links are sensibilized by cysteine hydrochloride.
Miul'
E M
EM
Zhil'tsova
V M
VM
Biniukov
V I
VI
D000818:Animals; D002843:Chromatin / Q000032:analysis / Q000187:drug effects / Q000528:radiation effects*; D003432:Cross-Linking Reagents / Q000494:pharmacology*; D004247:DNA / Q000032:analysis / Q000187:drug effects / Q000528:radiation effects*; D006657:Histones / Q000032:analysis / Q000187:drug effects / Q000528:radiation effects*; D066298:In Vitro Techniques; D051381:Rats; D014466:Ultraviolet Rays
D002843:Chromatin; D003432:Cross-Linking Reagents; D006657:Histones; D004247:DNA
UF-indutsirovannoe obrazovanie sshivok DNK-belok v khromatine v prisutstvii khimicheskikh agentov.