title: 5-Azacytidine treatments in the characterization of a t(1;21)(q12;q22) carrier karyotype.
abstract: A 46,XX,t(1;21)(q12;q22) carrier was ascertained because of two abortions. The non-reciprocal nature of the rearrangement was demonstrated in 5-azacytidine treated preparations with highly decondensed and somatically paired heterochromatic regions.
authors.forename: D
authors.initials: D
authors.lastname: Schindler
authors.forename: T
authors.initials: T
authors.lastname: Haaf
authors.forename: M
authors.initials: M
authors.lastname: Schmid
mesh_terms: D000328:Adult; D001374:Azacitidine; D002900:Chromosomes, Human, 1-3; D002904:Chromosomes, Human, 21-22 and Y; D005260:Female; D006579:Heterozygote; D006801:Humans; D007621:Karyotyping / Q000379:methods; D014178:Translocation, Genetic
chemical_list: D001374:Azacitidine