title: [Changes of the cytogenetic effectiveness of the therapeutic ray of fast neutrons in water phantoms].
abstract: Changes of cytogenetic effectiveness of the therapeutic ray of fast neutrons were studied in water phantom in the Medical-Biological Complex of CyclotronU-120 at the Institute for Nuclear Research of the Academy of Sciences of the Ukrainian SSR. Investigations were done in a culture of lymphocytes of the peripheral human blood by means of metaphase method to find out chromosomal aberrations. The neutrons were generated by firing a thick beryllium target with a 13.6 MeV-deuteron ray in the nuclear reaction 9Be (d,n) 10B. The investigated dose range was 25-220 cGy. The results of the studies demonstrate that the cytogenetic effectiveness of radiation is reduced with increasing depth of the water phantom. The maximum reduction of the effect was seen in a depth up to 6 cm, which is attached to absorption of low-energetic neutron fraction. The obtained results confirm necessity of to filter the therapeutically applicable beam of neutron radiation.
authors.forename: G M
authors.initials: GM
authors.lastname: Gulko
authors.forename: E A
authors.initials: EA
authors.lastname: Djomina
authors.forename: V A
authors.initials: VA
authors.lastname: Cernicenko
mesh_terms: D002478:Cells, Cultured; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000528:radiation effects*; D003903:Deuterium; D006801:Humans; D008214:Lymphocytes / Q000528:radiation effects*; D009502:Neutrons
chemical_list: D003903:Deuterium
vernacular_title: Veränderungen der zytogenetischen Effektivität des therapeutischen Strahles von schnellen Neutronen im Wasserphantom.