[Cytotoxic action of the interferons produced by the cells of newborn and sexually mature animals].
The results of investigations produced in newborn and adult animals revealed age-related differences in the activity of lactate dehydrogenase and its isoenzyme fractions. An increase in the total lactate dehydrogenase activity was observed in both cases, the maximum activity being achieved on the third day of observation. Besides, after the introduction of interferon from newborn animals an increase in the activity of fraction LDH-2 was observed, while the introduction of interferon from adult animals produced an increase in the activity of fraction LDH-5.
Malinovskaia
V V
VV
Litovchenko
V G
VG
Balandin
I G
IG
D000281:Administration, Intranasal; D000818:Animals; D000831:Animals, Newborn / Q000276:immunology*; D003602:Cytotoxicity, Immunologic; D007372:Interferons / Q000276:immunology* / Q000302:isolation & purification; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000097:blood; D051379:Mice; D012741:Sexual Maturation
D007527:Isoenzymes; D007372:Interferons; D007770:L-Lactate Dehydrogenase
Tsitotoksicheskoe deĭstvie interferonov, produtsiruemykh kletkami novorozhdennykh i polovozrelykh zhivotnykh.