Granular cell tumors contain myelin-associated glycoprotein. An immunohistochemical study using Leu 7 monoclonal antibody.
An immunohistochemical staining procedure using Leu 7 (HNK-1) monoclonal antibody was used to study the distribution of myelin-associated glycoprotein in granular cell tumours. Positive reactions were noted in 10 of the 13 tumours investigated. This observation supports the concept that granular cell tumours are of Schwann cell origin.
Smolle
J
J
Konrad
K
K
Kerl
H
H
D000818:Animals; D000911:Antibodies, Monoclonal; D006651:Histocytochemistry; D006801:Humans; D007124:Immunoenzyme Techniques; D051379:Mice; D008807:Mice, Inbred BALB C; D009185:Myelin Proteins / Q000032:analysis*; D018992:Myelin-Associated Glycoprotein; D009379:Neoplasms, Muscle Tissue / Q000032:analysis* / Q000473:pathology; D012583:Schwann Cells / Q000473:pathology
D000911:Antibodies, Monoclonal; D009185:Myelin Proteins; D018992:Myelin-Associated Glycoprotein