title: [Changes in lactate dehydrogenase activity in chicken tissues in hyperthyreosis in ontogenesis].
abstract: The lactate dehydrogenase activity in reactions of lactate oxidation and synthesis was studied in subfractions of the chicken brain, heart and liver at the embryonal, early postembryonal and adult stages of development after thyroxine administration. It has been shown that during embryogenesis thyroxine predominantly enhanced the rate of lactate oxidation in the mitochondrial tissues. A marked increase in the lactate synthesis was found in cytoplasm of the adult chicken tissues. Specificity of enzyme activity alterations was detected in the chicken brain during ontogenesis after thyroxine administration.
authors.forename: G G
authors.initials: GG
authors.lastname: Batkian
authors.forename: L A
authors.initials: LA
authors.lastname: Arutiunian
authors.forename: A A
authors.initials: AA
authors.lastname: Simonian
mesh_terms: D000818:Animals; D001921:Brain / Q000187:drug effects / Q000201:enzymology*; D002642:Chick Embryo; D002645:Chickens / Q000254:growth & development; D006980:Hyperthyroidism / Q000201:enzymology*; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D008929:Mitochondria, Heart / Q000187:drug effects / Q000201:enzymology*; D008930:Mitochondria, Liver / Q000187:drug effects / Q000201:enzymology*; D013974:Thyroxine / Q000494:pharmacology
chemical_list: D007770:L-Lactate Dehydrogenase; D013974:Thyroxine
vernacular_title: Izmeneniia aktivnosti laktatdegidrogenazy v tkaniakh kur pri gipertireoze v ontogeneze.