title: Detection of sperm-bound antibodies in the male partners of infertile couples using the immunobead test.
abstract: The aim of this investigation was to determine the incidence of sperm-bound antibodies in the male partners of an unselected infertile population using an immunologically specific test (IBT). With this method 34 out of 450 infertile men (7.55%) were positive for one or more of the immunoglobulins IgA, IgG and IgM. For IgG and IgA, the majority of antibody binding was located on the entire sperm with a minor amount bound to the head or tail. For the IgM, the majority of the binding was detected to the tail tip, and tail binding was observed only in a minority of cases.
authors.affiliation: Second Department of Obstetrics and Gynecology, University of Athens, Areteion Hospital, Greece.
authors.forename: O
authors.initials: O
authors.lastname: Gregoriou
authors.forename: N
authors.initials: N
authors.lastname: Vitoratos
authors.forename: N
authors.initials: N
authors.lastname: Legakis
authors.forename: G
authors.initials: G
authors.lastname: Gregoriou
authors.forename: P A
authors.initials: PA
authors.lastname: Zourlas
mesh_terms: D006801:Humans; D007132:Immunoglobulin Isotypes / Q000032:analysis*; D007159:Immunologic Tests; D007248:Infertility, Male / Q000175:diagnosis* / Q000276:immunology; D008297:Male; D013084:Sperm-Ovum Interactions / Q000276:immunology; D013094:Spermatozoa / Q000032:analysis* / Q000276:immunology
chemical_list: D007132:Immunoglobulin Isotypes