Localization of two alkaline phosphatase genes to the proximal region of mouse chromosome 1.
Using a human cDNA clone encoding the intestinal form of alkaline phosphatase, we have identified and mapped by RFLP analysis in a Mus spretus x C57BL/6J interspecies backcross two alkaline phosphatase genes which segregate independently on the proximal part of mouse Chromosome 1. The gene order and intergene distances were determined by standard backcross analysis as: centromere- Len-2 - 19.0 cM - Akp-3 - 20.0 cM - Akp-4 - 2.0 cM - Ren-1.
Schurr
E
E
Department of Biochemistry, McGill University, Montreal, Quebec, Canada.
Henthorn
P S
PS
Harris
H
H
Skamene
E
E
Gros
P
P
D000469:Alkaline Phosphatase / Q000235:genetics*; D000818:Animals; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D015342:DNA Probes; D006801:Humans; D051379:Mice; D008810:Mice, Inbred C57BL; D012150:Polymorphism, Restriction Fragment Length
D015342:DNA Probes; D000469:Alkaline Phosphatase