title: Sjögren's syndrome: association with type-1 diabetes mellitus.
abstract: This study of 102 unselected type-1 diabetic patients has shown that sicca symptoms affect 55% of the patients, although sometimes only during hyperglycaemic phases. While these symptoms might be attributable to the diabetes, the frequency of antinuclear antibodies in those suspected of having Sjögren's (25% by HEp-2) and particularly anti-Ro antibodies (32% by ELISA) reinforces the suspicion that Sjögren's syndrome may underlie their presence.
authors.affiliation: Bloomsbury Rheumatology Unit, University College, London.
authors.forename: A
authors.initials: A
authors.lastname: Binder
authors.forename: P J
authors.initials: PJ
authors.lastname: Maddison
authors.forename: P
authors.initials: P
authors.lastname: Skinner
authors.forename: A
authors.initials: A
authors.lastname: Kurtz
authors.forename: D A
authors.initials: DA
authors.lastname: Isenberg
mesh_terms: D000293:Adolescent; D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D005260:Female; D006801:Humans; D006943:Hyperglycemia; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology
chemical_list: D000974:Antibodies, Antinuclear