title: Low brain magnesium in migraine.
abstract: Brain magnesium was measured in migraine patients and control subjects using in vivo 31-Phosphorus Nuclear Magnetic Resonance Spectroscopy. pMg and pH were calculated from the chemical shifts between Pi, PCr and ATP signals. Magnesium levels were low during a migraine attack without changes in pH. We hypothesize that low brain magnesium is an important factor in the mechanism of the migraine attack.
authors.forename: N M
authors.initials: NM
authors.lastname: Ramadan
authors.forename: H
authors.initials: H
authors.lastname: Halvorson
authors.forename: A
authors.initials: A
authors.lastname: Vande-Linde
authors.forename: S R
authors.initials: SR
authors.lastname: Levine
authors.forename: J A
authors.initials: JA
authors.lastname: Helpern
authors.forename: K M
authors.initials: KM
authors.lastname: Welch
mesh_terms: D000328:Adult; D001923:Brain Chemistry; D005260:Female; D006801:Humans; D008274:Magnesium / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000175:diagnosis*; D010761:Phosphorus Radioisotopes
chemical_list: D010761:Phosphorus Radioisotopes; D008274:Magnesium