Vitiligo therapy with oral and topical phenylalanine with UVA exposure.
The administration of phenylalanine (Phe) combined with UVA exposure was found to be effective in treating vitiligo. Twenty-one patients with vitiligo were divided in two groups: eleven patients were treated with oral L-Phe in a dose of 100 mg/kg body weight and with UVA exposure and ten patients were treated with oral L-Phe in a dose of 100 mg/kg body weight and with UVA exposure. In addition, in the second group, a cream containing 10% L-Phe was applied to the vitiliginous areas. The best results occurred in the second group. No side effects were found in either group.
Antoniou
C
C
Dermatologic Clinic of Athens University, Andreas-Sygros Hospital, Greece.
Schulpis
H
H
Michas
T
T
Katsambas
A
A
Frajis
N
N
Tsagaraki
S
S
Stratigos
J
J
D000284:Administration, Oral; D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011701:PUVA Therapy; D010649:Phenylalanine / Q000008:administration & dosage*; D013997:Time Factors; D014820:Vitiligo / Q000628:therapy*
D010649:Phenylalanine