title: Lymphoma and hypercalcemia in a pediatric orthotopic liver transplant patient.
abstract: We present a case report of a pediatric orthotopic liver transplant recipient who developed lymphoma with hypercalcemia on cyclosporine and prednisone immunosuppression. This is the first reported posttransplant lymphoproliferative disorder complicated by hypercalcemia, with a finding of an elevated 1,25 dihydroxyl vitamin D state, suggesting that it has a role in the pathophysiology of this B cell lymphoma hypercalcemia. The clinical course and management of this disorder with a 31-month follow-up are described.
authors.affiliation: Transplant Service, San Francisco, CA 94120.
authors.forename: P
authors.initials: P
authors.lastname: Nakazato
authors.forename: C O
authors.initials: CO
authors.lastname: Esquivel
authors.forename: A H
authors.initials: AH
authors.lastname: Urbach
authors.forename: L
authors.initials: L
authors.lastname: Makowka
authors.forename: V
authors.initials: V
authors.lastname: Scantlebury
authors.forename: R
authors.initials: R
authors.lastname: Jaffe
authors.forename: T E
authors.initials: TE
authors.lastname: Starzl
mesh_terms: D002117:Calcitriol / Q000097:blood; D002675:Child, Preschool; D006084:Graft Rejection; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D016031:Liver Transplantation / Q000009:adverse effects*; D008223:Lymphoma / Q000209:etiology*; D008297:Male; D011183:Postoperative Complications / Q000209:etiology*
chemical_list: D002117:Calcitriol