HLA class I antigens in severe RSV bronchiolitis.
Cytotoxic T-lymphocytes (CTL) recognize virus-infected cells in association with HLA class I antigens. There is strong evidence of the importance of CTL in respiratory syncytial virus (RSV) infections. We looked for but were unable to demonstrate an association between particular HLA class I antigens and severe RSV bronchiolitis in infants.
Isaacs
D
D
Department of Paediatrics, John Radcliffe Hospital, Oxford, U.K.
Taylor
C J
CJ
Ting
A
A
McMichael
A J
AJ
D001990:Bronchiolitis, Viral / Q000276:immunology*; D002648:Child; D004198:Disease Susceptibility; D006680:HLA Antigens / Q000032:analysis*; D015234:HLA-A Antigens / Q000032:analysis; D015235:HLA-B Antigens / Q000032:analysis; D006801:Humans; D007223:Infant; D012136:Respiratory Syncytial Viruses; D010253:Respirovirus Infections / Q000276:immunology*
D006680:HLA Antigens; D015234:HLA-A Antigens; D015235:HLA-B Antigens