title: Lack of predictive value of HbA1 for impaired glucose tolerance in polycystic ovary syndrome.
abstract: Twenty-seven women with polycystic ovary syndrome (PCO) and 17 control women had a 75 g oral glucose tolerance test (oGTT) performed. Although glucose tolerance was impaired in the obese (body mass index greater than 25 kg/m2) women with PCO, glycosylated hemoglobin (HbA1) concentrations did not exceed the normal upper limit (7.2%). In all 44 women, there was no correlation between HbA1 and fasting glucose (r = 0.082, p = 0.63) but there was a significant correlation between HbA1 and summed glucose levels through the oGTT (r = 0.389, p = 0.02). HbA1 measurement does not predict the presence of impaired glucose tolerance in women with PCO.
authors.affiliation: Department of Obstetrics and Gynaecology, University Hospital of South Manchester, UK.
authors.forename: I M
authors.initials: IM
authors.lastname: Golland
authors.forename: C A
authors.initials: CA
authors.lastname: Vaughan Williams
authors.forename: S M
authors.initials: SM
authors.lastname: Shalet
authors.forename: L H
authors.initials: LH
authors.lastname: Million
authors.forename: M
authors.initials: M
authors.lastname: Elstein
mesh_terms: D000328:Adult; D001835:Body Weight; D005260:Female; D005951:Glucose Tolerance Test; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D011085:Polycystic Ovary Syndrome / Q000097:blood*; D011237:Predictive Value of Tests; D012307:Risk Factors
chemical_list: D006442:Glycated Hemoglobin