Toxicological data after heroin overdose.
Capillary gas chromatography with selective nitrogen detection was employed to quantify morphine and 6-monoacetylmorphine in biological fluids and tissues in five deaths attributed to heroin injection overdose. The minimum lethal concentration found was 0.021 micrograms morphine per ml of blood. In all cases, 6-monoacetylmorphine was identified in urine, confirming heroin abuse.
Kintz
P
P
Institut de Médecine Légale, Strasbourg, France.
Mangin
P
P
Lugnier
A A
AA
Chaumont
A J
AJ
D000328:Adult; D002849:Chromatography, Gas; D003932:Heroin / Q000378:metabolism / Q000493:pharmacokinetics / Q000506:poisoning*; D006801:Humans; D008297:Male; D009020:Morphine / Q000493:pharmacokinetics / Q000652:urine; D009022:Morphine Derivatives / Q000652:urine; D014018:Tissue Distribution
D009022:Morphine Derivatives; D003932:Heroin; D009020:Morphine; C026979:6-O-monoacetylmorphine