A case of mania secondary to propafenone.
A case of mania secondary to the administration of a new antiarrhythmic, propafenone, is described. This is a previously unrecognized potential complication in the use of this agent. Since propafenone is chemically related to a new antidepressant, bupropion, it may possess some antidepressant activity and thus have the potential to produce affective psychiatric side effects.
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D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D001714:Bipolar Disorder / Q000139:chemically induced* / Q000523:psychology; D016642:Bupropion; D005117:Cardiac Complexes, Premature / Q000188:drug therapy; D005260:Female; D006801:Humans; D011405:Propafenone; D011427:Propiophenones / Q000009:adverse effects* / Q000633:toxicity; D011605:Psychoses, Substance-Induced / Q000209:etiology* / Q000523:psychology
D000889:Anti-Arrhythmia Agents; D011427:Propiophenones; D016642:Bupropion; D011405:Propafenone