title: [A spectrophotometric method of analysis of fusidic acid].
abstract: A spectrophotometric method for assay of fusidic acid is described. The method is based on reaction with a reagent consisting of acetic anhydride and concentrated sulfuric acid. Mathematical processing of the results of the main substance determination in fusidic acid preparations showed that the error did not exceed 2 per cent. Procedures for spectrophotometric assay of fusidic acid in control of the processes of its biosynthesis, isolation and purification were developed. The procedures provided control of the technological process of fusidic acid production.
authors.forename: D E
authors.initials: DE
authors.lastname: Satarova
authors.forename: V B
authors.initials: VB
authors.lastname: Korchagin
authors.forename: V V
authors.initials: VV
authors.lastname: Stepushkina
authors.forename: R A
authors.initials: RA
authors.lastname: Makarova
mesh_terms: D000089:Acetic Anhydrides / Q000494:pharmacology; D004345:Drug Industry / Q000592:standards*; D005672:Fusidic Acid / Q000032:analysis* / Q000302:isolation & purification; D007202:Indicators and Reagents / Q000494:pharmacology; D008433:Mathematics; D011786:Quality Control; D013053:Spectrophotometry / Q000379:methods*; D013464:Sulfuric Acids / Q000494:pharmacology; D014586:USSR
chemical_list: D000089:Acetic Anhydrides; D007202:Indicators and Reagents; D013464:Sulfuric Acids; D005672:Fusidic Acid
vernacular_title: Spektrofotometricheskiĭ metod opredeleniia fuzidievoĭ kisloty.