[The lipid composition and aggregating capacity of thrombocytes in hyper- and hypothyroidism].
The aim of the work was to investigate the phospholipid composition and parameters of platelet aggregation in patients with hypo- and hyperthyroidism. The data obtained have shown that phospholipid liposomes added exogenously, changed the function of cell hemostasis and, in particular, decreased platelet aggregation. Unlike the other phospholipids, phosphatidylinositol, cardiolipin and phosphatidylserine produced the most significant effect on this index and corrected, to a certain extent, disturbed platelet functions in hypothyroidism.
Saipov
T D
TD
Aripov
D A
DA
Khashimova
R M
RM
Abduzhamilov
A A
AA
Saatov
T S
TS
D000244:Adenosine Diphosphate; D001792:Blood Platelets / Q000378:metabolism*; D002855:Chromatography, Thin Layer; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood*; D007037:Hypothyroidism / Q000097:blood*; D008055:Lipids / Q000097:blood*; D010743:Phospholipids / Q000097:blood; D010974:Platelet Aggregation / Q000187:drug effects / Q000502:physiology*; D010975:Platelet Aggregation Inhibitors
D008055:Lipids; D010743:Phospholipids; D010975:Platelet Aggregation Inhibitors; D000244:Adenosine Diphosphate
Lipidnyĭ sostav i agregatsionnaia sposobnost' trombotsitov pri giper- i gipotireoze.