title: [The role of changes in central and intracardiac hemodynamics in lowering the physical work capacity of patients with ischemic heart disease and diabetes mellitus].
abstract: The data of bicycle ergometry test and echocardiography were studied and compared in patients with postinfarction cardiosclerosis and type II diabetes mellitus without the clinical signs of heart failure. The patients showed the decreased work fitness and the identity of cardiovascular responses to graded exercise, pointing to the common character of the pathogenesis of these diseases. Both groups of the patients manifested the hyperkinetic type of the central hemodynamics as well as the lowering of the rate of diastolic relaxation and the rise of the end diastolic volume of the left ventricle. The intracardiac hemodynamics of coronary heart disease was characterized, in addition, by the reduction of myocardial contractility of the left ventricle due to focal injuries to the myocardial structures, which are more pronounced than in diabetes mellitus.
authors.forename: A P
authors.initials: AP
authors.lastname: Zaev
authors.forename: R P
authors.initials: RP
authors.lastname: Ol'kha
authors.forename: S A
authors.initials: SA
authors.lastname: Khar'kov
authors.forename: I E
authors.initials: IE
authors.lastname: Sofieva
authors.forename: A N
authors.initials: AN
authors.lastname: Kozin
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003327:Coronary Disease / Q000175:diagnosis / Q000503:physiopathology*; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis / Q000503:physiopathology*; D004185:Disability Evaluation; D004452:Echocardiography; D004562:Electrocardiography; D006321:Heart / Q000503:physiopathology*; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000503:physiopathology; D005082:Physical Exertion / Q000502:physiology
vernacular_title: Rol' izmeneniĭ tsentral'noĭ i vnutriserdechnoĭ gemodinamiki v snizhenii fizicheskoĭ rabotosposobnosti u bol'nykh ishemicheskoĭ bolezn'iu serdtsa i sakharnym diabetom.