A case of congenital factor XIII deficiency.
The case of a 53 years old woman was described in whom a congenital factor XIII deficiency was suspected because of deforming scars and hemorrhagic diathesis. A thromboelastographic declination of elasticity as well as decreased factor XIII level up to 5% of normal range were only found in all hemostatic examinations. In 2 children factor XIII decreased to half of its normal level, whereas in the youngest daughter that level was 25%. Sporadically the girl had mild diathesis. No changes in thromboelastograms were observed in members of the patient's family. The platelet function was unchanged in all examined cases.
Czestochowska
E
E
Luka
K
K
D005177:Factor XIII Deficiency / Q000151:congenital* / Q000235:genetics; D005260:Female; D006801:Humans; D008875:Middle Aged; D010375:Pedigree