title: [A dermaerosion case dealing with a leakage of a chemically irrigable solution (NaOCI solution)].
abstract: This paper is a report regarding a dermaerosion case dealing with a leakage of a chemically irrigable solution in a 3 year old boy. We are continuing to observe the dermal changes during as he grows. Also, we carried out a pathological experiment on a rabbit and a patch test of the derm of seven people. The following conclusions were obtained. 1. We observed the dermaerosion of an epithelium repair after a complete elapse of one year. The dermaerosion of the corium could not be repaired but changed the color of the derma of the patient who recovered after a lapse of 2 years and 8 months. 2. We recognized in the rabbit experiment that a 12% H2O2 solution damaged the corium of the rabbit over a period of 24 hours. The 12% H2O2 solution was four times higher, for we normally used a 3% H2O2 solution. 3. When we used a 10% NaOCl solution (which we usually use in the widening of the root canal) for 20 minutes on the derma of the rabbit, the derma damaged the epithelium but over a period of 40 minutes the solution we used on the derma of the rabbit damaged the corium. 4. When we used a NaOCl and H2O2 solution the reaction on the skin of the rabbit is weaker than when only one solution was used. 5. We used 0.5% NaOCl and 0.3% H2O2 solutions for the biceps of 2 atopic diseased people and 5 normal people for 48 hours, with no change noticed in their biceps. 6. The results may be summarized as follows.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.forename: T
authors.initials: T
authors.lastname: Ogura
authors.forename: S
authors.initials: S
authors.lastname: Hinotume
authors.forename: H
authors.initials: H
authors.lastname: Nishida
authors.forename: M
authors.initials: M
authors.lastname: Waseda
authors.forename: M
authors.initials: M
authors.lastname: Tashiro
mesh_terms: D000818:Animals; D002675:Child, Preschool; D005145:Face / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011817:Rabbits; D012388:Root Canal Irrigants / Q000009:adverse effects*; D012867:Skin / Q000187:drug effects*
chemical_list: D012388:Root Canal Irrigants