title: Do connective tissue components induce plasma activation in vivo?
abstract: 1. This paper describes the effect of homologous plasma in contact with connective tissue on vascular permeability, edema and cell migration. 2. The contact of "non-activated" plasma with connective tissue structures does not result in generation of mediators responsible for increase in vascular permeability or in edema. 3. "Activated" plasma is able to induce vascular permeability and edema when in contact with connective tissue components. 4. Injection of "non-activated" or "activated" plasma induced a mild inflammatory cell migration.
authors.affiliation: Departamento de Patologia, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, Brasil.
authors.forename: M R
authors.initials: MR
authors.lastname: Baccaro
authors.forename: M
authors.initials: M
authors.lastname: Mariano
authors.forename: B E
authors.initials: BE
authors.lastname: Malucelli
mesh_terms: D000818:Animals; D002199:Capillary Permeability; D002465:Cell Movement; D003238:Connective Tissue / Q000648:ultrastructure*; D004487:Edema / Q000209:etiology*; D005260:Female; D008297:Male; D009504:Neutrophils / Q000502:physiology; D010949:Plasma / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains