[Dynamic function of the recanalized coronary artery in patients with myocardial infarct undergoing thrombolytic therapy].
In order to study the efficacy of thrombolytic therapy from the standpoint of preserving contractile function of the left ventricle myocardium, the time course of changes in residual stenosis of the recanalized coronary artery was assessed in 36 patients with myocardial infarction. It has been shown that residual stenosis of the infarction-bound coronary artery determines in many respects the degree of preserving contractile function of the myocardium in cases of successful coronary thrombolysis. In approximately 50% of the cases of the recovery of the coronary blood flow under the action of streptokinase, residual stenosis of the infarction-bound artery regressed by day 28 of the disease. However, contractile function of the left ventricle myocardium may be expected to be preserved during successful thrombolysis only in cases where residual stenosis of the recanalized vessel regresses rapidly (within the first 24 hours since the occurrence of an anginal attack).
Savchenko
A P
AP
Pomerantsev
E V
EV
Smirnov
A A
AA
D015901:Angiography, Digital Subtraction; D003251:Constriction, Pathologic / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000503:physiopathology; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000503:physiopathology*; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects / Q000502:physiology; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000503:physiopathology*; D015425:Myocardial Reperfusion / Q000379:methods*; D012074:Remission Induction; D012189:Retrospective Studies; D013997:Time Factors
D005343:Fibrinolytic Agents
Dinamika sostoianiia rekanalizirovannoĭ koronarnoĭ arterii u bol'nykh infarktom miokarda pri tromboliticheskoĭ terapii.