title: [Cytotoxic action of the interferons produced by the cells of newborn and sexually mature animals].
abstract: The results of investigations produced in newborn and adult animals revealed age-related differences in the activity of lactate dehydrogenase and its isoenzyme fractions. An increase in the total lactate dehydrogenase activity was observed in both cases, the maximum activity being achieved on the third day of observation. Besides, after the introduction of interferon from newborn animals an increase in the activity of fraction LDH-2 was observed, while the introduction of interferon from adult animals produced an increase in the activity of fraction LDH-5.
authors.forename: V V
authors.initials: VV
authors.lastname: Malinovskaia
authors.forename: V G
authors.initials: VG
authors.lastname: Litovchenko
authors.forename: I G
authors.initials: IG
authors.lastname: Balandin
mesh_terms: D000281:Administration, Intranasal; D000818:Animals; D000831:Animals, Newborn / Q000276:immunology*; D003602:Cytotoxicity, Immunologic; D007372:Interferons / Q000276:immunology* / Q000302:isolation & purification; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000097:blood; D051379:Mice; D012741:Sexual Maturation
chemical_list: D007527:Isoenzymes; D007372:Interferons; D007770:L-Lactate Dehydrogenase
vernacular_title: Tsitotoksicheskoe deĭstvie interferonov, produtsiruemykh kletkami novorozhdennykh i polovozrelykh zhivotnykh.