title: Platelet monoamine oxidase-B activity in Parkinson's disease.
abstract: Platelet MAO-B levels have been investigated in seventeen consecutively diagnosed and previously untreated patients with idiopathic Parkinson's disease using the non-hydroxylated catecholamine, beta-phenylethylamine, as substrate. Patients with Parkinson's disease had MAO-B activity levels that were considerably higher than sex and age matched normal controls or patients with Motor neurone disease or Myasthenia gravis.
authors.affiliation: Department of Neurology, Queen Elizabeth Medical Centre, Birmingham, United Kingdom.
authors.forename: G B
authors.initials: GB
authors.lastname: Steventon
authors.forename: S G
authors.initials: SG
authors.lastname: Sturman
authors.forename: M T
authors.initials: MT
authors.lastname: Heafield
authors.forename: R H
authors.initials: RH
authors.lastname: Waring
authors.forename: J
authors.initials: J
authors.lastname: Napier
authors.forename: A C
authors.initials: AC
authors.lastname: Williams
mesh_terms: D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000201:enzymology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008995:Monoamine Oxidase / Q000378:metabolism*; D010302:Parkinson Disease, Secondary / Q000097:blood* / Q000201:enzymology
chemical_list: D008995:Monoamine Oxidase