title: [Changes in the immunotropic activity of neutrophilokins in the course of experimental staphylococcal infection].
abstract: The influence of the products secreted by activated neutrophils (neutrophilokins) of mice, both intact and infected with staphylococci, on the activity of mouse spleen cells in the graft-versus-host reaction, immune response to sheep red blood cells and the antigen-presenting function of peritoneal macrophages was studied. Neutrophilokins of intact mice stimulated the activity of immunocompetent cells. Neutrophilokins obtained from infected mice on day 3 after infection produced an immunosuppressing effect. On day 7 after infection the immunostimulating activity of neutrophils was restored and showed practically no difference from the normal level.
authors.forename: A V
authors.initials: AV
authors.lastname: Vlasov
authors.forename: A V
authors.initials: AV
authors.lastname: Zurochka
authors.forename: I I
authors.initials: II
authors.lastname: Dolgushin
mesh_terms: D000818:Animals; D000921:Antibody-Producing Cells / Q000276:immunology; D001202:Ascitic Fluid / Q000166:cytology / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology; D007114:Immunization; D008222:Lymphokines / Q000276:immunology* / Q000378:metabolism; D051379:Mice; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009504:Neutrophils / Q000276:immunology* / Q000637:transplantation; D013154:Spleen / Q000276:immunology; D013203:Staphylococcal Infections / Q000276:immunology*; D013997:Time Factors
chemical_list: D008222:Lymphokines
vernacular_title: Izmenenie immunotropnoĭ aktivnosti neĭtrofilokinov v techenie éksperimental'noĭ stafilokokkovoĭ infektsii.