title: Chronic progressive external ophthalmoplegia (CPEO) with 'ragged red fibers'--a case report.
abstract: Chronic progressive external ophthalmoplegia (CPEO) is a rare clinical syndrome characterized by slowly progressive paralysis of extraocular muscles. We report a male patient who had a 20 year history of CPEO. Histological examination of left deltoid muscle showed characteristic ragged red fibers. Electron microscopy revealed a number of abnormal mitochondria which contain paracrystalline inclusion bodies.
authors.affiliation: Department of Neurology, Asan Medical Center, Seoul, Korea.
authors.forename: J S
authors.initials: JS
authors.lastname: Kim
authors.forename: C J
authors.initials: CJ
authors.lastname: Kim
authors.forename: J G
authors.initials: JG
authors.lastname: Chi
authors.forename: H J
authors.initials: HJ
authors.lastname: Myung
mesh_terms: D001706:Biopsy; D002908:Chronic Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D008928:Mitochondria / Q000648:ultrastructure; D009132:Muscles / Q000648:ultrastructure; D009886:Ophthalmoplegia / Q000175:diagnosis* / Q000473:pathology