[Clinical assessment and prognosis of the complications of the corticosteroid therapy of Addison's disease patients].
Clinical and mathematical analysis was used for clinical assessment of specificities of the frequency of manifestations and combinations of complications in 87 patients with Addison's disease on corticosteroid therapy. Probability of the appearance of at least one of several complications or the combined appearance of several complications was established. The appearance of at least one of several complications in combination of excess body mass with other complications of the circulatory and digestive systems as well as one of several cardiovascular disorders could be predicted with the highest probability. Arbitrary discontinuation of corticosteroid therapy did not cause immediate clinical signs of the abolishment syndrome though in increased the probability of addisonian crisis development.
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D000224:Addison Disease / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D000328:Adult; D002648:Child; D006801:Humans; D008875:Middle Aged; D011336:Probability; D011379:Prognosis; D013375:Substance Withdrawal Syndrome / Q000175:diagnosis / Q000209:etiology; D013997:Time Factors
D000305:Adrenal Cortex Hormones
Klinicheskaia otsenka i prognozirovanie oslozhneniĭ kortikosteroidnoĭ terapii bol'nykh addisonovoĭ bolezn'iu.