title: Lys- and Tyr-arylamidase activities in serum and brain during the estrous cycle of the rat.
abstract: Peptidase enzymes are involved in neuropeptide processing or degradation. In order to analyse a possible functional participation of these enzymes, arylamidase activity of several rat brain regions and serum was assayed in the soluble fraction during the estrous cycle using L-Lys- and L-Tyr-beta-naphthylamide as substrates. Significant differences were present in the hypothalamus, the pituitary and serum when both substrates were used. However, there were no differences in cortical areas. These results suggest a role for arylamidase activity in the hormonal changes that happen during the estrous cycle of the rat.
authors.affiliation: Department of Physiology, Medical School, University of the Basque Country, Spain.
authors.forename: J M
authors.initials: JM
authors.lastname: de Gandarias
authors.forename: L
authors.initials: L
authors.lastname: Casis
authors.forename: J
authors.initials: J
authors.lastname: Irazusta
authors.forename: E
authors.initials: E
authors.lastname: Echevarría
authors.forename: G
authors.initials: G
authors.lastname: Arechaga
authors.forename: M
authors.initials: M
authors.lastname: Ramírez
mesh_terms: D000626:Aminopeptidases / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000201:enzymology*; D002540:Cerebral Cortex / Q000201:enzymology; D004971:Estrus / Q000502:physiology*; D005260:Female; D007031:Hypothalamus / Q000201:enzymology; D010902:Pituitary Gland / Q000201:enzymology; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D000626:Aminopeptidases