title: Synthesis and pharmacological properties of phenoxyethylpiperazine derivatives.
abstract: Salts of new 1-phenoxyethylpiperazines 1-5, their 4-amidine derivatives 6-10 and 4-phenoxyacetyl derivatives 11-15 have been obtained. Some of them were screened for their cardiovascular activity.
authors.affiliation: Department of Pharmaceutical Chemistry, Medical Academy, Kraków, Poland.
authors.forename: Z
authors.initials: Z
authors.lastname: Ryznerski
authors.forename: A
authors.initials: A
authors.lastname: Zejc
authors.forename: P
authors.initials: P
authors.lastname: Chevallet
authors.forename: B
authors.initials: B
authors.lastname: Cebo
authors.forename: J
authors.initials: J
authors.lastname: Krupińska
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002317:Cardiovascular Agents / Q000138:chemical synthesis* / Q000633:toxicity; D055598:Chemical Phenomena; D002621:Chemistry; D006321:Heart / Q000187:drug effects; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D009200:Myocardial Contraction / Q000187:drug effects; D010879:Piperazines / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D051381:Rats; D011919:Rats, Inbred Strains; D012119:Respiration / Q000187:drug effects; D013055:Spectrophotometry, Infrared
chemical_list: D002317:Cardiovascular Agents; D010879:Piperazines