[Immunohistochemical demonstration of tumor-associated antigens in urinary bladder carcinomas using mono- and polyclonal antisera].
Keratin was found in more than 90% of transitional cell carcinomas of the bladder in the cytoplasma with polyclonal antibodies. Intensity increased with dedifferentiation. Cytokeratin was detected with monoclonal antibodies in more than 80%. Squamous cell carcinoma of the urinary bladder was always strongly positive for keratin and cytokeratin. CEA was found in 20% of G1 and 40% of G2 and G3 carcinomas of the urinary bladder. The prostatic epithelium markers PSA and PAP were always negative also Ca1.
Friedmann
W
W
Steffens
J
J
Lobeck
H
H
D000135:Acid Phosphatase / Q000032:analysis; D000906:Antibodies / Q000032:analysis; D000951:Antigens, Neoplasm / Q000032:analysis*; D002272:Carcinoembryonic Antigen / Q000032:analysis; D002294:Carcinoma, Squamous Cell / Q000276:immunology*; D002295:Carcinoma, Transitional Cell / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007633:Keratins / Q000032:analysis; D008297:Male; D011467:Prostate / Q000201:enzymology; D017430:Prostate-Specific Antigen; D001749:Urinary Bladder Neoplasms / Q000276:immunology*
D000906:Antibodies; D000951:Antigens, Neoplasm; C038104:Ca1 antibody; D002272:Carcinoembryonic Antigen; D007633:Keratins; D000135:Acid Phosphatase; D017430:Prostate-Specific Antigen
Immunhistochemische Darstellung tumorassoziierter Antigene bei Harnblasenkarzinomen mit mono- und polyklonalen Antiseren.