title: Airway compromise after carotid surgery in patients with cervical irradiation.
abstract: Symptomatic carotid atherosclerotic disease occurring as a result of cervical irradiation often requires surgical intervention. Airway obstruction is an uncommon problem after most carotid surgery and has not been described for patients with cervical irradiation. Airway obstruction developed after two of five carotid endarterectomy procedures in previously irradiated necks requiring emergency tracheostomy or reintubation. Mechanisms of obstruction included endotracheal tube trauma to the fixed irradiated vocal cords and laryngeal edema caused by surgical dissection in an irradiated field. In addition, one patient in our series demonstrated hypercarbia as a result of bilateral carotid body ablation, a process known to impair the ventilatory response to hypoxia. An increased risk of airway obstruction after carotid surgery exists in patients with prior cervical irradiation. Preventive methods include the use of perioperative steroids and either carotid surgery with local anesthesia or bronchoscopic vocal cord visualization and intubation.
authors.affiliation: Thomas Jefferson University Hospital, Philadelphia, PA.
authors.forename: J W
authors.initials: JW
authors.lastname: Francfort
authors.forename: S N
authors.initials: SN
authors.lastname: Smullens
authors.forename: J F
authors.initials: JF
authors.lastname: Gallagher
authors.forename: R M
authors.initials: RM
authors.lastname: Fairman
mesh_terms: D000368:Aged; D000402:Airway Obstruction / Q000209:etiology*; D001161:Arteriosclerosis / Q000601:surgery; D002339:Carotid Arteries / Q000601:surgery*; D002340:Carotid Artery Diseases / Q000601:surgery; D004691:Endarterectomy; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal; D008297:Male; D008875:Middle Aged; D009333:Neck / Q000528:radiation effects*; D011183:Postoperative Complications; D011832:Radiation Injuries / Q000150:complications / Q000601:surgery; D012307:Risk Factors; D014140:Tracheotomy