title: Helium-neon laser-induced respiratory burst of phagocytic cells.
abstract: The effect of He-Ne laser radiation (lambda = 632.8 nm, I = 6.8 W/m2, irradiation time from 5 to 50 sec) on kinetics of spontaneous and Candida ablicans-stimulated chemiluminescence of mouse spleen cells was studied. It was found that laser radiation caused significant enhancement (180-250%) both of spontaneous chemiluminescence and Candida-induced chemiluminescence. The effective dose interval ranges from 100 to 300 J/m2, with a maximum at 200 J/m2. This finding shows that He-Ne laser irradiation can induce the respiratory burst (generation of reactive oxygen species having bactericidal activity) of phagocytic cells.
authors.affiliation: Laser Technology Center of Academy of Science, Moscow Region, Troitzk, Union of Soviet Socialist Republics.
authors.forename: T I
authors.initials: TI
authors.lastname: Karu
authors.forename: T P
authors.initials: TP
authors.lastname: Ryabykh
authors.forename: G E
authors.initials: GE
authors.lastname: Fedoseyeva
authors.forename: N I
authors.initials: NI
authors.lastname: Puchkova
mesh_terms: D000818:Animals; D004307:Dose-Response Relationship, Radiation; D007834:Lasers; D008163:Luminescent Measurements; D051379:Mice; D008815:Mice, Inbred Strains; D010101:Oxygen Consumption / Q000528:radiation effects*; D010586:Phagocytes / Q000528:radiation effects*; D010587:Phagocytosis / Q000528:radiation effects*