[DNA amplification in the study of polymorphisms linked to the cystic fibrosis gene].
The highly specific polymerase chain reaction recently described can be used to amplify selectively several polymorphic regions of DNA genetically close to the cystic fibrosis gene. This method, providing automated, revolutionizes the classical methods of prenatal diagnosis and carrier detection.
Claustres
M
M
Bellet
H
H
Desgeorges
M
M
Kjellberg
P
P
Toueri
M F
MF
Rollin
B
B
Bonnet
H
H
D002897:Chromosomes, Human, Pair 7; D003550:Cystic Fibrosis / Q000235:genetics*; D008040:Genetic Linkage; D006801:Humans; D010375:Pedigree; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D011296:Prenatal Diagnosis
Amplification de l'ADN dans létude des polymorphismes liés au gène de la mucoviscidose.