title: Unique allelic restriction fragments of the human Ha-ras locus in leukocyte and tumour DNAs of cancer patients.
abstract: White blood cell DNA from cancer patients and DNA from tumours and tumour-derived cell lines frequently demonstrated allelic restriction fragments of the Harvey ras oncogene locus not found in the unaffected population. The presence of such unusual alleles may be linked to susceptibility to cancer.
authors.forename: T G
authors.initials: TG
authors.lastname: Krontiris
authors.forename: N A
authors.initials: NA
authors.lastname: DiMartino
authors.forename: M
authors.initials: M
authors.lastname: Colb
authors.forename: D R
authors.initials: DR
authors.lastname: Parkinson
mesh_terms: D000483:Alleles; D002460:Cell Line; D002874:Chromosome Mapping; D004247:DNA / Q000032:analysis*; D004262:DNA Restriction Enzymes / Q000378:metabolism; D004273:DNA, Neoplasm / Q000032:analysis*; D015245:Deoxyribonuclease BamHI; D019003:Deoxyribonuclease HpaII; D005260:Female; D005838:Genotype; D006801:Humans; D007962:Leukocytes / Q000032:analysis; D009369:Neoplasms / Q000235:genetics; D011110:Polymorphism, Genetic
chemical_list: D004273:DNA, Neoplasm; D004247:DNA; D004262:DNA Restriction Enzymes; D015245:Deoxyribonuclease BamHI; D019003:Deoxyribonuclease HpaII