title: Nicotine dependence and tolerance in man: pharmacokinetic and pharmacodynamic investigations.
authors.forename: N L
authors.initials: NL
authors.lastname: Benowitz
authors.forename: H
authors.initials: H
authors.lastname: Porchet
authors.forename: P
authors.initials: P
authors.lastname: Jacob
mesh_terms: D001921:Brain / Q000187:drug effects; D004361:Drug Tolerance; D006801:Humans; D009538:Nicotine / Q000493:pharmacokinetics* / Q000494:pharmacology; D019966:Substance-Related Disorders / Q000378:metabolism*
chemical_list: D009538:Nicotine