title: Effects of SCH 23390 on thyrotropin-releasing hormone-induced behaviour in rabbits.
abstract: The influence of the dopamine D-1 receptor antagonist, SCH 23390, on thyrotropin-releasing hormone (TRH)-induced behaviour was assessed in adult male rabbits. SCH 23390 prevented the effects of TRH (100 micrograms i.c.v.), starting at a very low dose (0.01 mg/kg i.v.). This finding seems to indicate that dopamine D-1 receptors are involved in TRH-induced behaviour.
authors.affiliation: Department of Pharmacology, Istituto Superiore di Sanitù, Rome, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Popoli
authors.forename: M G
authors.initials: MG
authors.lastname: Caporali
authors.forename: A
authors.initials: A
authors.lastname: Scotti de Carolis
mesh_terms: D000818:Animals; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000494:pharmacology*; D001522:Behavior, Animal / Q000187:drug effects*; D001552:Benzazepines / Q000009:adverse effects / Q000494:pharmacology*; D007276:Injections, Intraventricular; D008297:Male; D011817:Rabbits; D013973:Thyrotropin-Releasing Hormone / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D014150:Antipsychotic Agents; D001552:Benzazepines; D013973:Thyrotropin-Releasing Hormone