Effect of elevation of body temperature on the electroretinogram of the rat.
The effect of elevation of body temperature on the electroretinogram of the rat was investigated in the dark-adapted state. A systematic decline in latency was noted as the body temperature was raised stepwise from 37 to 41 degrees C, averaging 1.9 ms degrees C-1. Maintenance of animals at a body temperature of 41 degrees C or greater led initially to increases in latency followed by decreases in amplitude. Hence, the electroretinogram shows similar changes to those reported for other sensory evoked potentials; it may therefore be a good candidate for use as a simpler model of the effects of hyperthermia on neural tissue.
Ahmed
B
B
Department of Physiology, Faculty of Medicine, University of Kuwait, Safat.
el-Wafai
S
S
Bana
L
L
D000818:Animals; D001831:Body Temperature / Q000502:physiology*; D003623:Dark Adaptation / Q000502:physiology; D004596:Electroretinography; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D011930:Reaction Time / Q000502:physiology; D012044:Regression Analysis