Cervical prostaglandin injection: a novel method of administration for ripening the cervix and induction of labor.
Twenty pregnant women with greater than or equal to 36 weeks gestation and Bishop score of less than or equal to 4 were subjected to either intracervical injection of PGE2 (0.25 mg) every 4 h to ripen the cervix and induce labor (study group n = 10) or injection of only the diluent (control group n = 10). PGE2 cases showed significant increase in Bishop score and were successfully induced. The mean induction-establishment and induction-delivery intervals were 4.3 +/- 0.1 min and 6.07 +/- 1.7 h, respectively. The control group showed no response. PGE2 cervical injection is a safe and effective method for cervical ripening and labor induction.
Shaala
S
S
Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria University, Egypt.
Darwish
E
E
Anwar
M
M
Rocca
M
M
Ismail
A A
AA
D000328:Adult; D002584:Cervix Uteri; D005260:Female; D006801:Humans; D007267:Injections / Q000379:methods; D007751:Labor, Induced / Q000379:methods*; D010298:Parity; D011247:Pregnancy; D011459:Prostaglandins E, Synthetic / Q000008:administration & dosage*
D011459:Prostaglandins E, Synthetic