[Extremely high alpha-fetoprotein levels in a puncture specimen with few cells following amniocentesis and interpretation by sonography].
We report on a prenatal diagnosis with high alpha-fetoprotein level and a positive acetylcholinesterase activity in a presumptive amniotic fluid. Ultrasonographic examinations revealed a hydropic fetus with a nuchal cystic hygroma. Chromosome analysis of the aborted foetus ascertained the suspected Turner syndrome. The highly elevated alpha-fetoprotein concentration and the positive acetylcholinesterase activity as well as the absence of the cells in the fluid make it clear, that the punctate originated from a cystic hygroma. Other cases from the literature are discussed.
Koske-Westphal
T
T
Müller-Holve
W
W
D000110:Acetylcholinesterase / Q000378:metabolism; D000328:Adult; D000649:Amniocentesis; D000653:Amniotic Fluid / Q000201:enzymology; D005260:Female; D006801:Humans; D007621:Karyotyping; D008423:Maternal Age; D010331:Paternal Age; D011247:Pregnancy; D018566:Pregnancy, High-Risk; D014424:Turner Syndrome / Q000175:diagnosis*; D014463:Ultrasonography; D000509:alpha-Fetoproteins / Q000378:metabolism*
D000509:alpha-Fetoproteins; D000110:Acetylcholinesterase
Extrem hoher Alpha-Fetoproteinspiegel in einem zellarmen Punktat nach Amniozentese und Klärung durch Sonographie.