Ifosfamide encephalopathy.
We describe a case of reversible encephalopathy caused by the recently released anticancer drug Ifosfamide. The clinical course, role of EEG in monitoring and predicting encephalopathy, and putative mechanism of neurotoxicity is discussed. Short infusion times and/or prior CNS disease may increase the risk of encephalopathy.
Danesh
M M
MM
Department of Neurology, USC School of Medicine, Los Angeles 90033.
De Giorgio
C M
CM
Beydoun
S R
SR
Kemp
R A
RA
D001927:Brain Diseases / Q000139:chemically induced*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage / Q000009:adverse effects*; D008875:Middle Aged; D012307:Risk Factors
D007069:Ifosfamide