title: Uptake of [3H]dopamine in the mouse adrenal medulla during dark and light period.
abstract: Uptake of exogenous [3H]dopamine in adrenal chromaffin cells of the mouse was studied by autoradiography under a 12-h light, 12-h dark cycle. The uptake of [3H]dopamine in adrenal chromaffin cells was markedly decreased in the dark period. The decrease was prevented by adrenal denervation. It is postulated that there is a neurally mediated suppression of [3H]dopamine uptake by adrenal chromaffin cells in the dark period. Adrenaline-storing (A) cells are more sensitive to the decreased sympathetic activity than noradrenaline-storing (NA) cells while increased sympathetic activity non-selectively affects both types of adrenal chromaffin cells.
authors.affiliation: Department of Physiology, Niigata University Medical School, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Hirano
authors.forename: K
authors.initials: K
authors.lastname: Nagai
authors.forename: T
authors.initials: T
authors.lastname: Bando
authors.forename: H
authors.initials: H
authors.lastname: Nakagawa
authors.forename: A
authors.initials: A
authors.lastname: Niijima
mesh_terms: D000313:Adrenal Medulla / Q000166:cytology / Q000378:metabolism*; D000818:Animals; D001345:Autoradiography; D002838:Chromaffin System / Q000166:cytology / Q000378:metabolism; D003624:Darkness; D004298:Dopamine / Q000378:metabolism*; D008027:Light; D008297:Male; D051379:Mice; D010507:Periodicity; D014316:Tritium
chemical_list: D014316:Tritium; D004298:Dopamine