Left ventricular volumes in moderate alcohol users: a study from the workplace.
We measured resting and exercise left ventricular volumes by a count-based, nongeometric radionuclide method in 23 healthy volunteers grouped according to reported average daily alcohol consumption: 0-20 g (Gp A), 21-50 g (Gp B) and greater than 50 g (Gp C). No patient had measurable alcohol in his blood at the time of study. Mean resting LV Ejection Fraction (EF) was 65 +/- 2% in Group A, 64 +/- 2% in Group B, and 65 +/- 3% in Group C. Exercise EF was 76 +/- 1,75 +/- 3 and 74 +/- 4%, respectively. Resting Endsystolic Volume Indices in the three groups were 19.2 +/- 3, 18.9 +/- 2 and 21.8 +/- 3 ml/m2; exercise values were 15.9 +/- 2, 12.8 +/- 2 and 13.3 +/- 2 ml/m2, respectively. This cohort was selected for absence of markers of alcohol-related illness, and all subjects were employed. We found no evidence for impaired left ventricular systolic function with moderate alcohol usage using a sensitive radionuclide technique.
Silberberg
J S
JS
Department of Cardiology, Prince Henry Hospital, Sydney.
Bowman
L K
LK
Murton
F J
FJ
Cranney
G B
GB
Walsh
W F
WF
Giles
R W
RW
D000328:Adult; D000428:Alcohol Drinking; D001794:Blood Pressure; D002306:Cardiac Volume; D004912:Erythrocytes; D005942:Gluconates; D006321:Heart / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006334:Heart Function Tests; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D009787:Occupational Medicine; D005082:Physical Exertion; D011877:Radionuclide Imaging; D013318:Stroke Volume; D013599:Systole
D005942:Gluconates