The Lynch syndrome; a high-risk factor for colorectal carcinoma.
Based on the case history of two patients, the problems of suspected familial colon carcinomas are discussed with special reference to screening policy and treatments. Upon identification of hereditary colon cancer (Lynch syndrome). treatment of the patient should consist of extensive resection and, if the patient is younger than 50 years, life-long careful follow-up.
Biert
J
J
Department of Surgery, Rijnstate GZ Hospital, Arnhem, The Netherlands.
Eggink
W F
WF
van Berge Henegouwen
G P
GP
Reuvers
C B
CB
D000328:Adult; D000367:Age Factors; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000601:surgery; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000175:diagnosis / Q000235:genetics* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D012307:Risk Factors