title: Toxoplasmosis: effectiveness of enzyme immunoassay screening.
abstract: The effectiveness of IgG enzyme-linked immunosorbent assays as serological screening tests for Toxoplasma gondii infection was investigated in three Scottish hospital laboratories. Three assays--two commercial and one produced by the Scottish Toxoplasma Reference Laboratory--were investigated. There was little difference in the sensitivity of the three tests (86-91%), but one of the commercial tests was markedly less specific. The performance of the more specific assays was improved by adjustment to an eight international unit per ml threshold.
authors.forename: A W
authors.initials: AW
authors.lastname: Joss
authors.forename: L J
authors.initials: LJ
authors.lastname: Skinner
authors.forename: J M
authors.initials: JM
authors.lastname: Chatterton
authors.forename: H A
authors.initials: HA
authors.lastname: Cubie
authors.forename: J F
authors.initials: JF
authors.lastname: Pryde
authors.forename: J D
authors.initials: JD
authors.lastname: Campbell
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D011237:Predictive Value of Tests; D014123:Toxoplasmosis / Q000175:diagnosis*
chemical_list: D000913:Antibodies, Protozoan