[Hospital epidemic of Clostridium difficile diarrhea: demonstration of cross-infection using a typing technic].
Two hospital outbreaks of Clostridium difficile diarrhoea in two general surgery units of different hospitals are described. Moreover, the results of a study on the circulation of C. difficile in a neurosurgery unit following two cases of colitis are reported. C. difficile strains isolated from patients and environment have been typed using antimicrobial susceptibility testing and electrophoretic profiles of EDTA-extracted proteins. The majority of strains isolated in each hospital shared the same protein profile and the same pattern of antibiotic susceptibility. This provides strong evidence of cross-infection and hospital acquisition of C. difficile.
Cerquetti
M
M
Pantosti
A
A
Gentile
G
G
D'Ambrosio
F
F
Mastrantonio
P
P
D001426:Bacterial Proteins / Q000032:analysis; D001427:Bacterial Toxins / Q000032:analysis; D003013:Clostridium / Q000145:classification / Q000302:isolation & purification; D003015:Clostridium Infections / Q000453:epidemiology*; D003092:Colitis / Q000453:epidemiology / Q000209:etiology* / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology*; D004196:Disease Outbreaks; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008826:Microbial Sensitivity Tests
D001426:Bacterial Proteins; D001427:Bacterial Toxins
Epidemie ospedaliere di diarrea da Clostridium difficile: dimostrazione di infezione crociata mediante tecniche di tipizzazione.