[Transplantation of the embryonic neocortex into the brain in rats: angioarchitecture of the graft 5 months after surgery].
In five adult rats into a bilateral, two-week old cavity in the sensorimotor cortex a homologous embryonic neocortex was implanted which was removed on the 14th day of gestation. The angioarchitecture was studied after a whole body injection of Indian ink into the host circulation. The regional capillarization in the transplant corresponded to construction principles of the graft. The neuron agglomerations which were arranged in a nodal pattern displayed the same capillary density as surrounding cerebral tissue. In the glial septa and in portions of the glial scar the capillary density was substantially lower. In zone I. representing a complete fusion of the neuropil between graft and recipient there was an inapparent and continuous transition of the capillary network. Also in the area of the glial scar (zone II) and the gliomeningeal scar (zone III) vascular connection was established.
Nĕmecek
S
S
Mazurová
Y
Y
Valousková
V
V
Mokrý
J
J
D000818:Animals; D001921:Brain / Q000098:blood supply*; D002540:Cerebral Cortex; D005333:Fetus; D009417:Nerve Tissue / Q000637:transplantation*; D051381:Rats
Transplantace embryonálního neokortexu do mozku potkana: angioarchitektonika stĕpu za 5 mĕsíců po operaci.