title: Severe immune thrombocytopenia and the development of skin infarctions in a patient with an overlap syndrome.
abstract: A 49-year-old woman with clinical features of systemic lupus erythematosus, systemic sclerosis, Sjögren's and the antiphospholipid syndromes developed severe immune thrombocytopenia and skin infarctions. Both complications responded to immunosuppressive agents.
authors.affiliation: Department of Medicine, University of the Witwatersrand Medical School, Johannesburg, South Africa.
authors.forename: P H
authors.initials: PH
authors.lastname: Dessein
authors.forename: R D
authors.initials: RD
authors.lastname: Lamparelli
authors.forename: S A
authors.initials: SA
authors.lastname: Phillips
authors.forename: I A
authors.initials: IA
authors.lastname: Rubenchik
authors.forename: S
authors.initials: S
authors.lastname: Zwi
mesh_terms: D001323:Autoantibodies / Q000032:analysis; D003095:Collagen Diseases / Q000150:complications / Q000276:immunology*; D005260:Female; D006801:Humans; D007238:Infarction / Q000209:etiology* / Q000276:immunology; D008875:Middle Aged; D008947:Mixed Connective Tissue Disease / Q000150:complications / Q000276:immunology; D009220:Myositis / Q000150:complications / Q000276:immunology*; D010743:Phospholipids / Q000276:immunology; D012867:Skin / Q000098:blood supply*; D013577:Syndrome; D013921:Thrombocytopenia / Q000150:complications / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D010743:Phospholipids