Regional localization of the sperm-specific lactate dehydrogenase, LDHC, gene on human chromosome 11.
A cDNA clone complementary to the mRNA encoding the sperm-specific lactate dehydrogenase, LDHC, has been used to map the LDHC locus to the short arm of human chromosome 11. In situ hybridization data and analysis of mouse/human somatic cell hybrids carrying deletions of human chromosome 11 suggest that the gene is localized at p15.3-p15.5 close to the LDHA gene.
Edwards
Y
Y
MRC Human Biochemical Genetics Unit, Galton Laboratory, University College London.
West
L
L
Van Heyningen
V
V
Cowell
J
J
Goldberg
E
E
D000818:Animals; D002460:Cell Line; D002874:Chromosome Mapping; D002880:Chromosomes, Human, Pair 11; D004247:DNA / Q000235:genetics; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000235:genetics*; D008297:Male; D051379:Mice; D009693:Nucleic Acid Hybridization; D015183:Restriction Mapping; D013094:Spermatozoa / Q000201:enzymology*
D004247:DNA; D007770:L-Lactate Dehydrogenase