[Parameters of cellular adaptation in newborn infants in health and in perinatal injuries of the CNS].
A study was made of the level of compensatory and adaptive reactions in red blood cells (intensity of membranous metabolism, lipid peroxidation, malonic dialdehyde (MDA) metabolism, changes in the correlation of lipid fractions) in the newborn in health and in perinatal CNS injuries within the first days of life. Changes in the indicated parameters were examined after preincubation of red blood cells under physiologic conditions and by means of MDA addition to the incubation medium. It is concluded that the newborn with perinatal CNS injuries are marked by metabolic inertness and reduced cellular adaptation in red blood cells preincubated under physiologic conditions as well as by pronounced disadaptation under the conditions of excess MDA.
Bankova
V V
VV
Gordeeva
G F
GF
Nikanorova
T M
TM
Tagieva
T A
TA
D000222:Adaptation, Physiological; D000367:Age Factors; D001720:Birth Injuries / Q000097:blood / Q000503:physiopathology*; D001930:Brain Injuries / Q000097:blood / Q000503:physiopathology*; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism*; D006801:Humans; D007231:Infant, Newborn; D015227:Lipid Peroxidation; D008315:Malondialdehyde / Q000097:blood / Q000494:pharmacology
D008315:Malondialdehyde
Pokazateli kletochnoĭ adaptatsii u novorozhdennykh v norme i pri perinatal'nykh povrezhdeniiakh TsNS.