title: [Endothelial function in contact lens-induced deep corneal opacities].
abstract: Deep stromal and preendothelial corneal opacities have been described to be a problem of growing importance in contact lens wearers, above all in those with a more than ten-year-old history of contact lens wearing. In the present study the corneal endothelial permeability of 21 patients with a more than ten-year-old history of contact lens (HEMA 38%) wearing has been determined and compared with that of an age-matched group of 8 healthy individuals without ocular disease. The corneal endothelial permeability has been measured by a computerized automated fluorophotometer (Coherent Radiation Fluorotron Master) after topical application of a Na-fluorescein solution according to the method described by Jones and Maurice. The corneal endothelial permeability of contact lens wearers with deep corneal opacities has been found to be significantly (p = 0.05) increased when compared with contact lens wearers without corneal opacities. Contact lens wearers without corneal opacities showed no significant increase of their endothelial permeability in comparison to the control group.
authors.forename: M
authors.initials: M
authors.lastname: Göbbels
authors.forename: A
authors.initials: A
authors.lastname: Wähning
authors.forename: M
authors.initials: M
authors.lastname: Spitznas
mesh_terms: D002463:Cell Membrane Permeability; D003261:Contact Lenses; D003318:Corneal Opacity / Q000473:pathology*; D003319:Corneal Stroma / Q000473:pathology; D004058:Diffusion; D004728:Endothelium, Corneal / Q000473:pathology*; D015590:Fluorophotometry; D006801:Humans; D014882:Water-Electrolyte Balance
vernacular_title: Endothelfunktion bei kontaktlinsenbedingten tiefen Hornhauttrübungen.