Malondialdehyde-like material and beta-thromboglobulin plasma levels in patients suffering from transient ischemic attacks.
Beta-thromboglobulin (betaTG) and malondialdehyde-like material (MDA-LM) plasma levels were studied in patients affected by transient ischemic attacks (TIA) after 2-4 months from the last episode. BetaTG and MDA-LM values were significantly higher in TIA patients than in 20 controls matched for age. No correlation between MDA-LM and betaTG was seen. This study suggests that in vivo platelet activation and, likely, increase of platelet cyclo-oxygenase activity can be detectable in TIA patients.
Francesco
V
V
Cesare
A
A
Luigi
I
I
Stefano
F
F
Andrea
G
G
Francesco
B
B
D000328:Adult; D000368:Aged; D001609:Beta-Globulins / Q000378:metabolism*; D001792:Blood Platelets / Q000378:metabolism / Q000502:physiology; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000097:blood*; D008297:Male; D008314:Malonates / Q000097:blood*; D008315:Malondialdehyde / Q000097:blood*; D008875:Middle Aged; D012008:Recurrence; D001620:beta-Thromboglobulin / Q000378:metabolism*
D001609:Beta-Globulins; D008314:Malonates; D001620:beta-Thromboglobulin; D008315:Malondialdehyde