Expression of the platelet-common acute lymphoblastic leukaemia associated antigen on normal eosinophils.
A murine monoclonal antibody (TP82) raised against normal platelets was found to be reactive with eosinophils and common acute lymphoblastic leukaemia (cALL) cells, and some blast cells from patients with non-lymphoid leukaemia. The antibody showed that the platelet-cALL associated antigen (p24) is also expressed on normal eosinophils, and may prove useful for studying the function as well as the differentiation of eosinophils.
Ohto
H
H
Shibata
Y
Y
Takeuchi
A
A
Chen
R F
RF
Maeda
H
H
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D000918:Antibody Specificity; D000951:Antigens, Neoplasm / Q000276:immunology*; D001667:Binding, Competitive; D001792:Blood Platelets / Q000276:immunology*; D002633:Chemotaxis; D004804:Eosinophils / Q000276:immunology*; D000939:Epitopes; D006801:Humans; D007945:Leukemia, Lymphoid / Q000276:immunology*; D051379:Mice / Q000276:immunology; D008807:Mice, Inbred BALB C
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D000939:Epitopes