Chronic progressive external ophthalmoplegia (CPEO) with 'ragged red fibers'--a case report.
Chronic progressive external ophthalmoplegia (CPEO) is a rare clinical syndrome characterized by slowly progressive paralysis of extraocular muscles. We report a male patient who had a 20 year history of CPEO. Histological examination of left deltoid muscle showed characteristic ragged red fibers. Electron microscopy revealed a number of abnormal mitochondria which contain paracrystalline inclusion bodies.
Kim
J S
JS
Department of Neurology, Asan Medical Center, Seoul, Korea.
Kim
C J
CJ
Chi
J G
JG
Myung
H J
HJ
D001706:Biopsy; D002908:Chronic Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D008928:Mitochondria / Q000648:ultrastructure; D009132:Muscles / Q000648:ultrastructure; D009886:Ophthalmoplegia / Q000175:diagnosis* / Q000473:pathology