Tamoxifen flare in advanced endometrial carcinoma.
Tamoxifen citrate has recently been shown to be effective palliative therapy in advanced endometrial carcinoma. Flare reactions from tamoxifen are well known in treatment of metastatic breast carcinoma and are not an indication for stopping therapy. We report a patient being treated with tamoxifen for advanced endometrial cancer who developed acute abdominal pain as a manifestation of a flare reaction and the significance of this observation.
Brooks
B J
BJ
Lippman
M E
ME
D000005:Abdomen; D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary; D000368:Aged; D005260:Female; D006801:Humans; D010146:Pain / Q000139:chemically induced; D010166:Palliative Care; D013629:Tamoxifen / Q000009:adverse effects*; D014594:Uterine Neoplasms / Q000188:drug therapy*
D013629:Tamoxifen