[Value of the study of the functional potential of neutrophils in suppurative, septic and allergic diseases in children].
A method for measuring the content of cationic proteins in neutrophil granulocytes of the peripheral blood was employed in patients with pyoseptic (n = 12) and allergic (n = 28) diseases during the exposure to composite infections in vitro. The method enables one to assess the functional potentialities of the cells in mobilizing the internal reserves and the readiness for the trigger of the cellular granular apparatus, for instance during real or predicted exposure of the child to bacterial infections. The determination of the functional potentialities of neutrophil phagocytes can be used as a test for the appraisal of the gravity of allergic and pyoseptic processes as well as for predicting outcomes of pyoseptic diseases.
Nesterova
I V
IV
Svetlichnaia
M A
MA
D000293:Adolescent; D001770:Blood Bactericidal Activity / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D009504:Neutrophils / Q000276:immunology*; D010019:Osteomyelitis / Q000276:immunology*; D011023:Pneumonia, Staphylococcal / Q000276:immunology*; D012130:Respiratory Hypersensitivity / Q000276:immunology*; D013203:Staphylococcal Infections / Q000276:immunology*; D013211:Staphylococcus aureus / Q000276:immunology
Znachenie issledovaniia funktsiona'lnogo potentsiala neĭtro- fi'lnykh granulotsitov pri gnoĭno-septicheskikh i allergiches- kikh zabolevaniiakh u deteĭ.