title: Application of continuous-flow liquid chromatography/fast-atom bombardment mass spectrometry to the analysis of diagnostic acylcarnitines in human urine.
abstract: Acylcarnitine profiles of diagnostic value were generated from the equivalent of 0.1 microL of raw urine using the continuous-flow liquid chromatography/fast-atom bombardment mass spectrometry (LC/FAB-MS) interface for sample introduction. Further analysis was accomplished by gradient LC/MS using a commercially available packed fused-silica microbore column.
authors.affiliation: Duke University Medical Center, Department of Pediatrics, Durham, North Carolina 27710.
authors.forename: D L
authors.initials: DL
authors.lastname: Norwood
authors.forename: N
authors.initials: N
authors.lastname: Kodo
authors.forename: D S
authors.initials: DS
authors.lastname: Millington
mesh_terms: D002331:Carnitine / Q000031:analogs & derivatives* / Q000652:urine; D002853:Chromatography, Liquid / Q000379:methods; D044943:Fatty Acid Desaturases / Q000172:deficiency; D045782:Hemiterpenes; D006801:Humans; D010421:Pentanoic Acids / Q000097:blood; D011422:Propionates / Q000097:blood; D016339:Spectrometry, Mass, Fast Atom Bombardment / Q000379:methods
chemical_list: D045782:Hemiterpenes; D010421:Pentanoic Acids; D011422:Propionates; C008216:isovaleric acid; D044943:Fatty Acid Desaturases; C029658:propionic acid; D002331:Carnitine