Tetraploidy and aneuploidy after observation of diploid fertilization in vitro.
A case is described in which a tetraploid and aneuploid conceptus resulted from dipronuclear embryos from in vitro fertilization. This finding strongly suggests that, after a meiotic error in either the egg or sperm, polyploidy has occurred as the result of a postfertilization mitotic error.
Bender
S D
SD
Genetics & IVF Institute, Fairfax, Virginia 22031.
Dorfmann
A D
AD
Schulman
J D
JD
Bustillo
M
M
D000328:Adult; D000782:Aneuploidy; D002824:Chorionic Villi / Q000032:analysis; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D011123:Polyploidy