Application of continuous-flow liquid chromatography/fast-atom bombardment mass spectrometry to the analysis of diagnostic acylcarnitines in human urine.
Acylcarnitine profiles of diagnostic value were generated from the equivalent of 0.1 microL of raw urine using the continuous-flow liquid chromatography/fast-atom bombardment mass spectrometry (LC/FAB-MS) interface for sample introduction. Further analysis was accomplished by gradient LC/MS using a commercially available packed fused-silica microbore column.
Norwood
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Duke University Medical Center, Department of Pediatrics, Durham, North Carolina 27710.
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Millington
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D002331:Carnitine / Q000031:analogs & derivatives* / Q000652:urine; D002853:Chromatography, Liquid / Q000379:methods; D044943:Fatty Acid Desaturases / Q000172:deficiency; D045782:Hemiterpenes; D006801:Humans; D010421:Pentanoic Acids / Q000097:blood; D011422:Propionates / Q000097:blood; D016339:Spectrometry, Mass, Fast Atom Bombardment / Q000379:methods
D045782:Hemiterpenes; D010421:Pentanoic Acids; D011422:Propionates; C008216:isovaleric acid; D044943:Fatty Acid Desaturases; C029658:propionic acid; D002331:Carnitine