Intracranial granulocytic sarcoma in postpolycythemia myeloid metaplasia.
A 57-year-old man with a ten-year history of polycythemia vera had myeloid metaplasia, extramedullary hematopoiesis, and terminally, possible leukemic transformation with intracranial granulocytic sarcoma. Radiation therapy produced a partial and temporary beneficial response. Intracranial granulocytic sarcoma is typically associated with acute or chronic myelogenous leukemia and has not been previously associated with postpolycythemia myeloid metaplasia.
Roy
E P
EP
Department of Neurology, West Virginia University School of Medicine, Morgantown 26506.
Rogers
J S
JS
Riggs
J E
JE
D001932:Brain Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D002540:Cerebral Cortex / Q000473:pathology; D003131:Combined Modality Therapy; D006801:Humans; D007951:Leukemia, Myeloid / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011087:Polycythemia Vera / Q000150:complications* / Q000473:pathology / Q000628:therapy; D012509:Sarcoma / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D013997:Time Factors; D014057:Tomography, X-Ray Computed