Toxic shock syndrome toxin-1 (TSST-1) production in staphylococcal infections and serological implications with patients and healthy controls.
TSST-1 production occurred in 4.6% among Staphylococcus aureus strains isolated from divergent clinical sources in South-West Hungary. Patients suffering from staphylococcal infections, whether or not harbouring TSST-1 positive strains, exhibited low anti TSST-1 titres in their acute phase sera compared to the healthy control population. A S. aureus strain isolated from toxic shock syndrome (TSS) was a high collagen binder and a low fibronectin and fibrinogen binder suggesting the role of connective tissue adhesion in colonization and low invasive property of TSS strains.
Naidu
A S
AS
Department of Medical Microbiology, University of Lund, Sweden.
Vörös
S
S
Löczi
G
G
Kienle
Z
Z
Brasch
B
B
Emödy
L
L
D001427:Bacterial Toxins; D003094:Collagen / Q000378:metabolism; D004768:Enterotoxins / Q000096:biosynthesis* / Q000276:immunology; D005260:Female; D005340:Fibrinogen / Q000378:metabolism; D005353:Fibronectins / Q000378:metabolism; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism; D008297:Male; D011485:Protein Binding; D013203:Staphylococcal Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000302:isolation & purification / Q000378:metabolism*; D018089:Superantigens
D001427:Bacterial Toxins; D004768:Enterotoxins; D005353:Fibronectins; D007074:Immunoglobulin G; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal; D005340:Fibrinogen; D003094:Collagen