title: [Ultrastructural changes in thyrocytes exposed to the antithyroid preparations betazin and diiodotyrosine].
abstract: Ultrastructure changes in the thyroid gland cells of rats were studied when feeding of bethazine and diiodthyrozine to rats at doses 0.01, 0.1 and 1.0 mg/kg of body's weight for 12 months. The ultrastructure changes in thyrocytes typical both for hyper- and for hypofunction of the gland were revealed.
authors.forename: V I
authors.initials: VI
authors.lastname: Trunov
authors.forename: A P
authors.initials: AP
authors.lastname: Tarasenko
authors.forename: T V
authors.initials: TV
authors.lastname: Pliuta
mesh_terms: D000818:Animals; D013956:Antithyroid Agents / Q000494:pharmacology*; D004105:Diiodotyrosine / Q000031:analogs & derivatives* / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D008297:Male; D008854:Microscopy, Electron; D051381:Rats; D013961:Thyroid Gland / Q000187:drug effects* / Q000648:ultrastructure; D013997:Time Factors
chemical_list: D013956:Antithyroid Agents; D004105:Diiodotyrosine; C045165:betazine
vernacular_title: Ul'trastrukturnye izmeneniia tirotsitov pri vozdeĭstvii antitireoidnykh preparatov--betazina i diĭodtirozina.