title: Computed tomography-measured trunk fat and plasma lipoprotein levels in nonobese women.
abstract: The associations between total adiposity, adipose tissue distribution measured by computed axial tomography (CAT), regional variation in fat cell size, and plasma lipoprotein levels were studied in a sample of 22 premenopausal healthy nonobese women aged 34.6 +/- 3.1 years (mean +/- SD) (% body fat, 27.8 +/- 5.8). In these nonobese women, no associations were found between total adiposity, adipose tissue distribution, and plasma triglyceride or very-low-density lipoprotein levels. However, total adiposity (as reflected by the body density-derived fat mass and by the adipose tissue volume measured by CAT), as well as the total trunk fat areas (measured at the abdominal and thoracic levels) were positively correlated with plasma low-density lipoprotein (LDL) cholesterol (.05 greater than P less than .01) and LDL apolipoprotein (apo) B (.05 greater than P less than .0005) levels. Because of these associations with LDL-C and LDL apo B levels, these body fatness indicators were negatively correlated with the HDL-cholesterol/LDL-cholesterol and HDL-apo A-I/LDL-apo B ratios. However, few significant associations were observed between the proportion of abdominal fat estimated by the waist/hip circumference ratio (WHR) and the lipoprotein-lipid profile (r = .45 and r = .44, P less than .05 with HDL triglyceride (TG) and LDL-apo B/LDL-cholesterol ratio, respectively).(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Medicine, Laval University, Ste-Foy, Quebec, Canada.
authors.forename: M C
authors.initials: MC
authors.lastname: Pouliot
authors.forename: J P
authors.initials: JP
authors.lastname: Després
authors.forename: S
authors.initials: S
authors.lastname: Moorjani
authors.forename: A
authors.initials: A
authors.lastname: Tremblay
authors.forename: P J
authors.initials: PJ
authors.lastname: Lupien
authors.forename: A
authors.initials: A
authors.lastname: Nadeau
authors.forename: G
authors.initials: G
authors.lastname: Thériault
authors.forename: C
authors.initials: C
authors.lastname: Bouchard
mesh_terms: D000005:Abdomen; D000273:Adipose Tissue / Q000166:cytology / Q000000981:diagnostic imaging / Q000378:metabolism*; D000328:Adult; D001053:Apolipoproteins / Q000097:blood; D005260:Female; D005951:Glucose Tolerance Test; D006615:Hip; D006801:Humans; D008074:Lipoproteins / Q000097:blood / Q000378:metabolism*; D013223:Statistics as Topic; D013909:Thorax; D014057:Tomography, X-Ray Computed
chemical_list: D001053:Apolipoproteins; D008074:Lipoproteins