Proteinuria, glomerulomegaly and focal glomerulosclerosis in a grossly obese man with obstructive sleep apnea syndrome.
A grossly obese (149 kg) man with the sleep apnea syndrome was found to have proteinuria and a supernormal glomerular filtration rate. Renal histology showed glomerulomegaly and focal glomerulosclerosis. It is suggested that obesity may induce glomerular hyperfiltration and in turn glomerulosclerosis.
Bailey
R R
RR
Department of Nephrology, Christchurch Hospital, New Zealand.
Lynn
K L
KL
Burry
A F
AF
Drennan
C
C
D000328:Adult; D005919:Glomerular Filtration Rate; D005921:Glomerulonephritis; D005923:Glomerulosclerosis, Focal Segmental / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology / Q000503:physiopathology; D008297:Male; D009767:Obesity, Morbid / Q000150:complications* / Q000503:physiopathology; D011507:Proteinuria / Q000150:complications* / Q000503:physiopathology; D012891:Sleep Apnea Syndromes / Q000150:complications* / Q000503:physiopathology