title: Ca2+ interaction with phospholipid bilayers studied by multifrequency phase fluorometry.
abstract: Calcium interaction with phospholipid membranes containing phosphatidic acid is studied by multifrequency phase fluorometry, using DPH as fluorescent molecule. DPH decay is analysed by a continuous distribution of lifetimes. The results suggest an increase of membrane heterogeneity at low calcium concentrations, without changes in the polarity of the environment surrounding the probe.
authors.affiliation: Institute of Biochemistry, Medical School, Ancona, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Zolese
authors.forename: G
authors.initials: G
authors.lastname: Curatola
mesh_terms: D002118:Calcium / Q000378:metabolism*; D004161:Diphenylhexatriene; D005470:Fluorometry; D008051:Lipid Bilayers / Q000378:metabolism*; D010712:Phosphatidic Acids / Q000378:metabolism; D010713:Phosphatidylcholines / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism*
chemical_list: D008051:Lipid Bilayers; D010712:Phosphatidic Acids; D010713:Phosphatidylcholines; D010743:Phospholipids; D004161:Diphenylhexatriene; D002118:Calcium