Uroporphyria caused by acetone and 5-aminolevulinic acid in iron-loaded mice.
Sinclair
P R
PR
VA Medical Center, White River Junction, VT 05001.
Bement
W J
WJ
Lambrecht
R W
RW
Jacobs
J M
JM
Sinclair
J F
JF
D000096:Acetone / Q000008:administration & dosage* / Q000494:pharmacology; D000622:Aminolevulinic Acid / Q000008:administration & dosage* / Q000494:pharmacology; D000818:Animals; D004195:Disease Models, Animal; D004347:Drug Interactions; D007505:Iron-Dextran Complex / Q000008:administration & dosage* / Q000494:pharmacology; D007982:Levulinic Acids / Q000008:administration & dosage*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology; D011164:Porphyrias / Q000139:chemically induced* / Q000201:enzymology; D011166:Porphyrins / Q000378:metabolism; D014575:Uroporphyrinogen Decarboxylase / Q000037:antagonists & inhibitors
D007982:Levulinic Acids; D011166:Porphyrins; D000096:Acetone; D000622:Aminolevulinic Acid; D007505:Iron-Dextran Complex; D014575:Uroporphyrinogen Decarboxylase