Laboratory evaluation of a double lumen catheter for venovenous neonatal ECMO.
The authors designed and tested a 14F outside diameter thin-walled double lumen catheter (DLC) for neonatal venovenous (VV) extracorporeal membrane oxygenation (ECMO). In vitro tests with water and dye solution showed capacity of the drainage lumen was 1,096 ml/min at 100 cm siphon, and pressure drop across the perfusion lumen was 300 mmHg at 500 ml/min flow. Recirculation at 500 ml/min flow ranged from 5 to 29%, depending upon simulated cardiac output. The highest serum hemoglobin during 12 hour 400 ml/min flow VV bypass in five dogs was 49 mg/dl. Typical oxygen transport in four dogs was 25 cc/min at 400 ml/min flow. This catheter is well suited for clinical VV ECMO in neonates.
Otsu
T
T
University of Michigan Medical School, Department of Surgery, Ann Arbor.
Merz
S I
SI
Hultquist
K A
KA
Attorri
R J
RJ
Anderson
H L
HL
Scheffler
D E
DE
Ahmad
A
A
Bartlett
R H
RH
D001783:Blood Flow Velocity; D002408:Catheters, Indwelling; D006801:Humans; D007231:Infant, Newborn; D007601:Jugular Veins; D008955:Models, Cardiovascular; D010100:Oxygen / Q000097:blood; D010107:Oxygenators, Membrane; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*; D014683:Vena Cava, Superior
D010100:Oxygen