[Immunodiagnosis of acute nonlymphoblastic leukemia in children].
Seventy-two children with acute nonlymphoblastic leukemia (ANLL) have been studied for expression of different antigens on blast cells with the use of monoclonal antibodies. Myeloid antigens (C3bi; X-hapten) were identified on blast cells most frequently, 58.3%, Ia-like antigen was found in 55% and LFA-1 in 34% of cases. The expression of all antigens except that of LFA-1 was independent on FAB-subtype. It seems necessary in clinical practice to type ANLL cells for the expression of T-cell and myeloid antigens that are of prognostic significance.
Tupitsyn
N N
NN
Baryshnikov
A Iu
AIu
Kadagidze
Z G
ZG
Maiakova
S A
SA
Protasova
A K
AK
Artem'ev
A K
AK
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm / Q000032:analysis; D002648:Child; D006801:Humans; D007159:Immunologic Tests; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis* / Q000276:immunology; D011379:Prognosis; D013601:T-Lymphocytes / Q000276:immunology
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm
Immunodiagnostika ostrogo nelimfoblastnogo leĭkoza u deteĭ.