[The effect of calypsol, thiopental sodium and fentanyl on the functional status of the sinoatrial node and the heart conduction system in patients with paroxysmal arrhythmias].
64 patients with paroxysmal arrhythmias caused in 44 cases by collateral atrioventricular pathways have been studied. Endocardial programmed electrical cardiostimulation was applied. It has been established that calypsol at a dose of 2 mg/kg significantly improves the functional state of the sinoatrial node, atrioventricular conduction and conduction in collateral atrioventricular pathways functioning both anterogradely and retrogradely. Fentanyl, already at a dose of 2.5 micrograms/kg inhibits considerably the functional state of the sinoatrial node, without affecting conduction in the normal AV system and in collateral atrioventricular pathways. Thiopental sodium at a dose of 7 mg/kg improves slightly the functional state of the sinoatrial node.
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D000293:Adolescent; D000328:Adult; D000777:Anesthetics / Q000494:pharmacology*; D005260:Female; D005283:Fentanyl / Q000494:pharmacology; D006329:Heart Conduction System / Q000187:drug effects* / Q000503:physiopathology; D006801:Humans; D007649:Ketamine / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D012849:Sinoatrial Node / Q000187:drug effects / Q000503:physiopathology; D013614:Tachycardia, Paroxysmal / Q000503:physiopathology*; D013874:Thiopental / Q000494:pharmacology
D000777:Anesthetics; D007649:Ketamine; D013874:Thiopental; D005283:Fentanyl
Vliianie kalipsola, tiopental-natriia i fentanila na funktsional'noe sostoianie sinoatrial'nogo uzla i provodiashcheĭ sistemy serdtsa u bol'nykh s paroksizmal'nymi narusheniiami serdechnogo ritma.