[Activity of gamma-glutamyltranspeptidase in clear cell carcinomas of the human kidney and renal cortex].
In 30 operated patients (23 men and 7 women) we determined the activity of GGTP in the tissue of renal clear-cell carcinomas and in their renal cortex. It was found that the enzyme activity was constantly lower in the tumours than in the spared kidney however with a correlation between the enhancement of GGTP activity in the renal cortex and clear-cell carcinomas originating in the tissue of the cortex. In contrast we did not observe a relation between the degree of morphological differentiation of the neoplasms and GGTP activity. The authors discuss the problem in the light of literature data.
Zawirska
B
B
Stolarczyk
J
J
Jeleń
M
M
D000230:Adenocarcinoma / Q000201:enzymology*; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007672:Kidney Cortex / Q000201:enzymology*; D007680:Kidney Neoplasms / Q000201:enzymology*; D008297:Male; D008875:Middle Aged; D005723:gamma-Glutamyltransferase / Q000378:metabolism*
D005723:gamma-Glutamyltransferase
Aktywność gamma-glutamylotranspeptydazy w jasnokomórkowych rakach nerki ludzkiej i w ich macierzystej korze nerkowej.