[Significance of plasma cells in the rejection of kidney grafts].
Authors studied with immunohistochemical methods the immunoglobulin content of plasma cells during the rejection of renal grafts, in different rejections, in Cyclosporin-A nephro-toxicity and in chronic interstitial nephritis, as a comparison. By far the most plasma cells occurred in chronic rejection, containing more than 80% IgG. Whereas great majority of plasma cells were IgG positive in chronic interstitial nephritis. Probably, in chronic rejection a special, secondary type humoral immune reaction has a significant role in addition to cellular immune mechanisms.
Nadasdy
T
T
Krenács
T
T
Kalmár-Nagy
K
K
Csajbók
E
E
Boda
K
K
D006084:Graft Rejection / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G; D007668:Kidney / Q000276:immunology / Q000473:pathology*; D016030:Kidney Transplantation / Q000276:immunology; D009395:Nephritis, Interstitial / Q000276:immunology; D010950:Plasma Cells / Q000276:immunology* / Q000473:pathology
D007074:Immunoglobulin G
A plasmasejtek jelentösége vesetranszplantátumok kilöködésében.