Tissue difference in cellular localization of thiamine phosphate esters.
1. Thiamine phosphate levels were determined in the soluble and particulate fractions of various rat tissues. 2. There was marked tissue difference in the cellular localization of thiamine phosphates. 3. Brain thiamine triphosphate was localized only in the particulate fraction, whereas skeletal muscle thiamine triphosphate was in the soluble fraction as a protein-unbound form.
Matsuda
T
T
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Osaka University, Japan.
Tonomura
H
H
Baba
A
A
Iwata
H
H
D000818:Animals; D001923:Brain Chemistry; D002458:Cell Fractionation; D007655:Ketoglutarate Dehydrogenase Complex / Q000378:metabolism; D007668:Kidney / Q000032:analysis; D008099:Liver / Q000032:analysis; D008297:Male; D009132:Muscles / Q000032:analysis; D009206:Myocardium / Q000032:analysis; D009928:Organ Specificity; D051381:Rats; D011919:Rats, Inbred Strains; D012995:Solubility; D013552:Swine; D013831:Thiamine / Q000031:analogs & derivatives* / Q000032:analysis*; D013835:Thiamine Pyrophosphate / Q000032:analysis*; D013838:Thiamine Triphosphate / Q000032:analysis*; D014174:Transketolase / Q000378:metabolism
D013838:Thiamine Triphosphate; D007655:Ketoglutarate Dehydrogenase Complex; D014174:Transketolase; D013835:Thiamine Pyrophosphate; D013831:Thiamine