Antigenic mimicry of mammalian intermediate filaments by mycoplasmas.
A murine monoclonal antibody raised against Mycoplasma hyorhinis specifically reacted by indirect immunofluorescence with mammalian intermediate filaments. The antibody recognized a related epitope on a 74,000-molecular-weight protein of M. hyorhinis and on components of similar size from other pathogenic mycoplasmas. This defines a shared antigenic structure of interest in autoantibody development during mycoplasmal diseases.
Wise
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KS
Watson
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D000818:Animals; D000911:Antibodies, Monoclonal; D000941:Antigens / Q000276:immunology*; D000942:Antigens, Bacterial / Q000276:immunology*; D002460:Cell Line; D006224:Cricetinae; D003429:Cross Reactions; D003599:Cytoskeleton / Q000276:immunology*; D000939:Epitopes / Q000276:immunology; D005455:Fluorescent Antibody Technique; D007668:Kidney; D009174:Mycoplasma / Q000276:immunology*
D000911:Antibodies, Monoclonal; D000941:Antigens; D000942:Antigens, Bacterial; D000939:Epitopes