[A study of bronchial sensitivity and bronchial reactivity using Astograph and transcutaneous oxygen tension in asthmatic children. The problems of simultaneous measurement].
Bronchial sensitivity and reactivity in 60 patients with bronchial asthma was measured using the Astograph and simultaneous transcutaneous oxygen tension [PtcO2]. In spite of increasing respiratory resistance, there were some cases in which PtcO2 did not show remarkable decrease. The PtcO2 percentage was defined as (basal value of PtcO2 - bottom value of PtcO2)/(basal value of PtcO2). The correlation between PtcO2% and the basal value of PtcO2 was relatively high (r = 0.42, n = 58, p less than 0.005). The correlation between PtcO2% and V50/Ht or V25/Ht was also relatively high (r = 0.41, n = 45, p less than 0.01, r = 0.49, n = 45, p less than 0.001, respectively). In some cases of small airway obstruction or low basal value of PtcO2, was smaller. The patients of over 70% in FEV1.0/VCP were in accord with that of over 70 mmHg in the basal value of PtcO2. The results suggest the recommended basal value of PtcO2 to measure bronchial sensitivity and reactivity may be over 70 mmHg.
Ichinose
H
H
Mezawa
K
K
Miyamoto
M
M
Wakabayashi
T
T
D000293:Adolescent; D000328:Adult; D000403:Airway Resistance; D001249:Asthma / Q000097:blood / Q000503:physiopathology*; D001785:Blood Gas Monitoring, Transcutaneous; D001980:Bronchi / Q000503:physiopathology*; D002648:Child; D006801:Humans; D012130:Respiratory Hypersensitivity / Q000503:physiopathology*