title: Hemoglobin Hope found in a patient with basal cell carcinoma of the genial region.
abstract: Hemoglobinopathy was detected in a 72-year-old female with basal cell carcinoma of the genial region during high-performance liquid chromatography of hemolysate for the assay of HbA1c. Structural analysis demonstrated that this abnormal hemoglobin was identical to Hb Hope [beta 136(H14)Gly----Asp]. No clinical or hematological abnormality was observed. A study of the family revealed that a younger sister and two sons of the propositus had the same hemoglobin variant. This is the second observation of Hb Hope in a Japanese family.
authors.forename: E
authors.initials: E
authors.lastname: Araki
authors.forename: Y
authors.initials: Y
authors.lastname: Wada
authors.forename: K
authors.initials: K
authors.lastname: Ishihara
authors.forename: S
authors.initials: S
authors.lastname: Ueda
authors.forename: K
authors.initials: K
authors.lastname: Harano
authors.forename: T
authors.initials: T
authors.lastname: Harano
mesh_terms: D000368:Aged; D002280:Basal Cell Carcinoma / Q000097:blood*; D002680:Chin; D005153:Facial Neoplasms / Q000097:blood*; D005260:Female; D006455:Hemoglobins, Abnormal / Q000032:analysis*; D006801:Humans
chemical_list: D006455:Hemoglobins, Abnormal; C038623:hemoglobin Hope