title: [The effect of pharmacologic therapy of hyperthyroidism on automatic heart conduction].
abstract: Investigations of the heart automatism were carried out in 10 patients with hyperthyreoidism before thiamazol therapy and after restoration of the euthyroid status. A control group was comprised of 34 healthy subjects. In order to determine the electrophysiologic parameters the transoesophageal atrium extrastimulus technique and the over-driving stimulation were applied. Restoration of the euthyroid status was accompanied by a significant prolongation of the atrial refraction, the border interval, the border conductivity and the sinus rhythm recurrence time. In a half of the patients were atrioventricular and intraventricular conductibility disturbances observed. The authors conclude, that in the early period of the euthyroid status restoration after thiamazole therapy there still exists a risk of cardiologic complications.
authors.affiliation: IV. Klinik für Innere Krankheiten der Schlesischen Medizinischen Akademie Katowice.
authors.forename: G
authors.initials: G
authors.lastname: Jonderko
authors.forename: C
authors.initials: C
authors.lastname: Marcisz
authors.forename: E
authors.initials: E
authors.lastname: Kocot
mesh_terms: D000328:Adult; D001145:Arrhythmias, Cardiac / Q000188:drug therapy; D002304:Cardiac Pacing, Artificial; D004305:Dose-Response Relationship, Drug; D004562:Electrocardiography; D005260:Female; D006329:Heart Conduction System / Q000187:drug effects*; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D006980:Hyperthyroidism / Q000188:drug therapy*; D008297:Male; D008713:Methimazole / Q000008:administration & dosage*; D013960:Thyroid Function Tests
chemical_list: D008713:Methimazole
vernacular_title: Der Einfluss der pharmakologischen Hyperthyreosetherapie auf die Herzautomatie.