Xeroderma pigmentosum: squamous cell carcinoma of the tongue.
A case report is presented of a 9-year-old boy with xeroderma pigmentosum complementation group C, who died from a squamous cell carcinoma arising from the tip of the tongue. Treatment with etretinate and in a later phase with indomethacin and prednisolone was not effective, except for a limited initial response of the tumour to etretinate.
Keukens
F
F
Department of Dermatology, University Hospital, Groningen, The Netherlands.
van Voorst Vader
P C
PC
Panders
A K
AK
Vinks
S
S
Oosterhuis
J W
JW
Kleijer
W J
WJ
D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000209:etiology*; D002648:Child; D005050:Etretinate / Q000627:therapeutic use; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D014062:Tongue Neoplasms / Q000188:drug therapy / Q000209:etiology*; D014983:Xeroderma Pigmentosum / Q000150:complications*
D005050:Etretinate; D011239:Prednisolone; D007213:Indomethacin