Connections between the sensory retina and the retinal pigment epithelium.
The study reports on the presence of connections between the visual receptor outer segments and the apical villi on the retinal pigment epithelium in the human eye. The mechanisms underlying sensory retinal adhesion to the pigment epithelium, recognition and attachment of visual receptor outer segments to the pigment epithelium during phagocytosis, and communication and transport of substances between the two layers of retina have been difficult to define, and molecular connections between the two layers of retina could play an important role in these processes.
Nicolaissen
B
B
D000368:Aged; D002462:Cell Membrane / Q000648:ultrastructure; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D005110:Extracellular Space / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010786:Photoreceptor Cells / Q000648:ultrastructure*; D010857:Pigment Epithelium of Eye / Q000648:ultrastructure*; D012160:Retina / Q000648:ultrastructure*; D012163:Retinal Detachment / Q000473:pathology; D013194:Staining and Labeling