title: [Effects of rabies infection on the metabolism of the host-cell: does inhibition of cellular RNA synthesis take place?].
abstract: Acute infection of cloned BHK21 cells with rabies virus (CVS strain) resulted in a reduction in the amount of cellular RNA, not so rapid and pronounced as with another rhabdovirus, vesicular stomatitis virus (VSV). This decrease in the amount of cellular RNA was shown to be caused by a differential membrane permeability of infected and uninfected BHK21 cells to [3H]-uridine and by a real inhibition of cellular RNA synthesis.
authors.forename: C
authors.initials: C
authors.lastname: Tuffereau
authors.forename: C
authors.initials: C
authors.lastname: Martinet-Edelist
mesh_terms: D000818:Animals; D002472:Cell Transformation, Viral; D002499:Centrifugation, Density Gradient; D002999:Clone Cells / Q000378:metabolism; D006224:Cricetinae; D007668:Kidney; D012313:RNA / Q000378:metabolism*; D011820:Rabies virus; D014529:Uridine / Q000378:metabolism
chemical_list: D012313:RNA; D014529:Uridine
vernacular_title: Effets de l'infection rabique sur le métabolisme de la cellule-hôte: y-a-t-il inhibition de la synthèse des ARN cellulaires?