title: A comparative study of animal erythrocyte agglutinins from marine algae.
abstract: 1. Fifteen marine algal species were analyzed for agglutinins to rabbit, sheep and human A, B and O blood group erythrocytes. 2. Protein extracts from all marine algae agglutinated rabbit erythrocytes, whereas twelve and five extracts agglutinated sheep and human erythrocytes, respectively. 3. The highest agglutination titers were consistently observed with rabbit erythrocytes. 4. Dictyota dichotoma strongly agglutinated human B blood group erythrocytes relative to A and O group erythrocytes. 5. Agglutination titer of rabbit erythrocytes by six algal extracts was not inhibited by mono- or polysaccharides, yet was reduced by glycoproteins.
authors.affiliation: Harbor Branch Oceanographic Institution, Division of Applied Biology, Fort Pierce, FL 34946.
authors.forename: T C
authors.initials: TC
authors.lastname: Chiles
authors.forename: K T
authors.initials: KT
authors.lastname: Bird
mesh_terms: D000818:Animals; D001789:Blood Group Antigens; D050260:Carbohydrate Metabolism; D002846:Chromatography, Affinity; D003208:Concanavalin A / Q000378:metabolism; D056890:Eukaryota / Q000032:analysis*; D006023:Glycoproteins / Q000494:pharmacology; D006385:Hemagglutination Inhibition Tests; D006386:Hemagglutination Tests; D006388:Hemagglutinins / Q000032:analysis* / Q000378:metabolism; D006801:Humans; D011817:Rabbits / Q000097:blood; D012756:Sheep / Q000097:blood
chemical_list: D001789:Blood Group Antigens; D006023:Glycoproteins; D006388:Hemagglutinins; D003208:Concanavalin A