title: Cardiac amyloidosis causing ventricular tachycardia. Diagnosis made by endomyocardial biopsy.
abstract: In patients with malignant ventricular arrhythmias, endomyocardial biopsy may be helpful when all other findings from the workup are negative. A case of nonsustained polymorphic ventricular tachycardia is presented. The findings from an echocardiogram, coronary angiogram, and cardiac catheterization were negative. An electrophysiologic study showed inducible nonsustained ventricular tachycardia. A right ventricular endomyocardial biopsy was diagnostic of cardiac amyloid. The findings from a workup for systemic amyloidosis were negative. Primary cardiac amyloidosis should be considered in patients with malignant arrhythmias and no documented heart disease, and endomyocardial biopsy is helpful in making this diagnosis.
authors.affiliation: Department of Cardiology, Midwest Heart Research Foundation, Downers Grove, IL.
authors.forename: N
authors.initials: N
authors.lastname: Stamato
authors.forename: J
authors.initials: J
authors.lastname: Cahill
authors.forename: M
authors.initials: M
authors.lastname: Goodwin
authors.forename: G
authors.initials: G
authors.lastname: Winters
mesh_terms: D000686:Amyloidosis / Q000150:complications* / Q000473:pathology; D001706:Biopsy; D009202:Cardiomyopathies / Q000150:complications* / Q000473:pathology; D004699:Endocardium / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D013610:Tachycardia / Q000209:etiology*