Toxoplasmosis: effectiveness of enzyme immunoassay screening.
The effectiveness of IgG enzyme-linked immunosorbent assays as serological screening tests for Toxoplasma gondii infection was investigated in three Scottish hospital laboratories. Three assays--two commercial and one produced by the Scottish Toxoplasma Reference Laboratory--were investigated. There was little difference in the sensitivity of the three tests (86-91%), but one of the commercial tests was markedly less specific. The performance of the more specific assays was improved by adjustment to an eight international unit per ml threshold.
Joss
A W
AW
Skinner
L J
LJ
Chatterton
J M
JM
Cubie
H A
HA
Pryde
J F
JF
Campbell
J D
JD
D000818:Animals; D000913:Antibodies, Protozoan / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D011237:Predictive Value of Tests; D014123:Toxoplasmosis / Q000175:diagnosis*
D000913:Antibodies, Protozoan