title: Neuro-rhinosurgical treatment of aesthesioneuroblastoma.
abstract: The results of a combined neuro-rhinosurgical procedure in eight cases of aesthesioneuroblastoma are presented. All patients were suffering from tumours in the advanced stage (stage C according to Kadish). Diagnosis was established by the clinical history, neuro-radiological imaging and by endoscopic endonasal biopsy. Contrary to most reports in the literature the authors performed a one step operative removal of the whole tumour mass by a combined transcranial-transbasal approach alone. A second transfacial operation was unnecessary in all our cases. To the best of our knowledge only Loew (see Jakumeit 1971) already in the 1960ties used a comparable one step transcranial approach for tumour removal. The long-term survival rate in our patients is 50%, a result comparable to reported series in the literature. Mortality is due to early recurrences and metastases within a few months after the initial treatment including post-operative irradiation. Four patients are living without evidence of tumour recurrence 1.5 to 5 years after treatment. The authors surgical technique is presented in detail and compared with the results of other treatment modalities.
authors.affiliation: Neurochirurgische Universitätsklinik, Universität Erlangen-Nürnberg, Federal Republic of Germany.
authors.forename: R
authors.initials: R
authors.lastname: Fahlbusch
authors.forename: U
authors.initials: U
authors.lastname: Neubauer
authors.forename: M
authors.initials: M
authors.lastname: Wigand
authors.forename: M
authors.initials: M
authors.lastname: Weidenbecher
authors.forename: G
authors.initials: G
authors.lastname: Röckelein
authors.forename: P
authors.initials: P
authors.lastname: Thierauf
authors.forename: R
authors.initials: R
authors.lastname: Sauer
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009447:Neuroblastoma / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D009493:Neurosurgery / Q000379:methods*; D009669:Nose Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*