title: Transient cortical blindness following cerebral angiography.
abstract: Transient cortical blindness following cerebral angiography was previously assumed to result from embolism or other factors impairing cortical perfusion during angiography. Contrast medium-induced disruption of the blood-brain barrier and a direct neurotoxic effect by contrast media have been proposed as a potential mechanism of neurotoxicity. Support of this concept has been provided by reports that demonstrate blood-brain barrier damage with postangiography computerized tomography in patients experiencing various acute neurologic sequelae of cerebral angiography including one case of transient cortical blindness. We report a case of transient cortical blindness following cerebral angiography in which computerized tomography documents blood-brain barrier disruption limited to the occipital lobes.
authors.forename: P B
authors.initials: PB
authors.lastname: Shyn
authors.forename: K A
authors.initials: KA
authors.lastname: Bell
mesh_terms: D000368:Aged; D001766:Blindness / Q000209:etiology*; D001812:Blood-Brain Barrier / Q000187:drug effects; D002533:Cerebral Angiography / Q000009:adverse effects*; D003974:Diatrizoate Meglumine / Q000009:adverse effects*; D006801:Humans; D008297:Male
chemical_list: D003974:Diatrizoate Meglumine