Initiation of labor with a moderately favorable cervix: a comparison between prostaglandin E2 gel and oxytocin.
This study compares prostaglandin E2 (PGE2) gel and oxytocin for the initiation of labor in term pregnancies with a moderately favorable cervix (Bishop score 5-8). Compared with a matched group, 48 cases treated with PGE2 gel (2.5 mg intravaginally) required significantly less or no oxytocin, had shorter first stages of active labor, and had no increased risk of uterine hyperstimulation or cesarean section. Initiation of labor with low dose PGE2 when the cervix is moderately favorable is less labor intensive and meets with more patient satisfaction.
Rayburn
W
W
Department of Obstetrics and Gynecology, University of Nebraska Medical Center, Omaha.
Woods
R
R
Eggert
J
J
Ramadei
C
C
D000328:Adult; D002584:Cervix Uteri / Q000187:drug effects; D005260:Female; D005782:Gels; D006801:Humans; D007747:Labor Stage, First / Q000187:drug effects; D007751:Labor, Induced / Q000379:methods*; D010121:Oxytocin / Q000008:administration & dosage* / Q000494:pharmacology; D011247:Pregnancy; D011459:Prostaglandins E, Synthetic / Q000008:administration & dosage* / Q000494:pharmacology
D005782:Gels; D011459:Prostaglandins E, Synthetic; D010121:Oxytocin