Effects of molybdenum on human enamel fluoride uptake and experimental rat dental caries.
The addition of high concentrations of molybdenum to a topically applied sodium fluoride solution did not result in a statistically significant increase in fluoride uptake into subsurface lesions in human enamel when compared to that after treatment with fluoride alone in vitro. The addition of 3000 parts/10(6) molybdenum to a 1000 parts/10(6) fluoride topical solution had no impact in vivo on the cariostatic activity of topically applied fluoride in rats.
Uemura
M
M
Department of Preventive Dentistry, Osaka Dental University, Japan.
Park
K K
KK
Stookey
G K
GK
Konishi
K
K
D000704:Analysis of Variance; D000818:Animals; D002327:Cariostatic Agents; D016009:Chi-Square Distribution; D003731:Dental Caries / Q000378:metabolism*; D003743:Dental Enamel / Q000187:drug effects / Q000378:metabolism*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008982:Molybdenum / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D012969:Sodium Fluoride / Q000008:administration & dosage / Q000493:pharmacokinetics*
D002327:Cariostatic Agents; D008982:Molybdenum; D012969:Sodium Fluoride