title: Acetylcholine receptor antibody in myasthenia gravis.
abstract: Radioimmunoassay techniques were used to detect antibodies to the acetylcholine receptor (AAChR) in 164 patients with adult-onset myasthenia gravis. AAChR levels above 0.6 nM/l were considered pathological and were found in 67% of the patients with an average value of 58.99 +/- 125.02 nM/l (0.6-900.0). Correlation, with clinical functional status, the histopathological thymus alterations and the different therapeutics used did not disclose any statistically significant differences.
authors.affiliation: Department of Neurology, São Paulo University Medical School, Brazil.
authors.forename: P E
authors.initials: PE
authors.lastname: Marchiori
authors.forename: M
authors.initials: M
authors.lastname: dos Reis
authors.forename: M E
authors.initials: ME
authors.lastname: Quevedo
authors.forename: M
authors.initials: M
authors.lastname: Scaff
authors.forename: W
authors.initials: W
authors.lastname: Cossermelli
authors.forename: J L
authors.initials: JL
authors.lastname: Assis
authors.forename: R M
authors.initials: RM
authors.lastname: de Oliveira
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001323:Autoantibodies / Q000276:immunology*; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D011950:Receptors, Cholinergic / Q000276:immunology*; D013950:Thymus Gland / Q000473:pathology* / Q000601:surgery
chemical_list: D000305:Adrenal Cortex Hormones; D001323:Autoantibodies; D002800:Cholinesterase Inhibitors; D011950:Receptors, Cholinergic