Effect of adenosine on fructose 2,6-bisphosphate levels and glucose metabolization by chicken erythrocytes.
Adenosine can be metabolized by chicken erythrocytes as a carbon source maintaining ATP levels. In addition, it stimulates glucose uptake and lactate production. Adenosine effects do not involve binding to membrane receptors. They are dependent on the provision of a carbon source to glycolysis and correlate with the increase of fructose 2,6-bisphosphate levels that activating phosphofructokinase would increase the glycolytic flux.
Espinet
C
C
Department of Ciéncies Fisiològiques, Humanes i de la Nutrició, Facultat de Medicina, Univesitat de Barcelona, Spain.
Bartrons
R
R
Carreras
J
J
D000241:Adenosine / Q000378:metabolism / Q000494:pharmacology*; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002645:Chickens; D004912:Erythrocytes / Q000378:metabolism*; D005635:Fructosediphosphates / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism*; D006019:Glycolysis / Q000187:drug effects; D006598:Hexosediphosphates / Q000378:metabolism*; D007773:Lactates / Q000378:metabolism
D005635:Fructosediphosphates; D006598:Hexosediphosphates; D007773:Lactates; C027652:fructose 2,6-diphosphate; D000255:Adenosine Triphosphate; D005947:Glucose; D000241:Adenosine