[Intake of water and sodium chloride solution by the rats after central administration of litorin and immunization with litorin-bovine serum albumin conjugate].
Central injection of litorin suppressed water and sodium chloride solution intake, and also decreased the preference of saline of unrestrained rats during 1 hour test. Active immunization of animals with litorin-bovine serum albumin conjugate led to the augmentation of their daily saline preference. Immunized rats increased also avidity to salt after deprivation, though the consumption volume of liquids decreased. The data, obtained on the immunized animals prove the importance of definite level of endogenous bombesin-like peptide in the salt appetite of rats. The central effect of litorin is discussed in the aspect of changing by it the evaluation of gustatory information.
Ishanov
P A
PA
Ashmarin
I P
IP
Esakov
A I
AI
Obukhova
M F
MF
Storozheva
Z I
ZI
Golubovich
V P
VP
Golubtsov
K V
KV
Kuznetsova
N V
NV
D000818:Animals; D001070:Appetitive Behavior / Q000187:drug effects*; D002552:Cerebral Ventricles; D004326:Drinking / Q000187:drug effects*; D007114:Immunization; D007267:Injections; D007274:Injections, Intraperitoneal; D008297:Male; D009842:Oligopeptides / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D012710:Serum Albumin, Bovine / Q000008:administration & dosage*; D012965:Sodium Chloride; D013649:Taste / Q000187:drug effects
D009842:Oligopeptides; D012710:Serum Albumin, Bovine; D012965:Sodium Chloride; C010212:litorin
Potreblenie vody i rastvora povarennoĭ soli krysami posle tsentral'nogo vvedeniia litorina i pri immunizatsii ikh kon"iugatom litorina s bych'im syvorotochnnym al'buminom.