[Autopsy results in surgical-radiotherapeutic treatment of bladder carcinoma--conclusions for optimal radiologic therapy].
With 282 autopsied patients with bladder carcinoma, that were treated by combined operation and radiotherapy, conclusions are given for tendency in tumor spreading as well as for complications and late-effects of radiotherapy. In 24.5% of the cases tumor tissue was found within the bladder and in 30.5% of the cases within the minor pelvis. Metastases were found in 24.1% in iliac lymph-nodes, in 21.3% of the autopsy cases in abdominal lymph-nodes. Liver, lungs, bones, and kidneys are main organs for hematological metastasizing. Little or undifferentiated carcinomas and squamous cell carcinomas show a greater tendency to metastasize than highly and medium-differentiated ureteral carcinomas. The least radiotherapeutical complications and late-effects were found in a fractionation with daily 1.5 Gy and a total dose of 60 Gy (necrotising urocystitis 17.9%, proctitis 3.6%).
Füller
J
J
Kob
D
D
Fritzsche
V
V
D002277:Carcinoma / Q000473:pathology / Q000532:radiotherapy* / Q000556:secondary; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy* / Q000556:secondary; D006801:Humans; D008207:Lymphatic Metastasis; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000532:radiotherapy*
Obduktionsbefunde beim operativ-strahlentherapeutisch behandelten Harnblasenkarzinom--Schlussfolgerungen für die radiologische Therapieoptimierung.