title: COBE Spectra Apheresis System: designs, protocols and results.
abstract: The COBE Spectra System will perform all types of apheresis procedures. One of its main procedures is to collect single donor platelets. Because of the unique abilities of this device, the procedures are individualized by the control of several algorithms. Prior to the beginning of the run, a platelet yield is predicted using the entered platelet count. Based upon this information, changes can be made in the operating parameters to optimize the collection. Leuko-poor thrombozytes are produced which can be stored for 5 days. The collect concentration monitor, an on-line device, provides information on the use of thrombocyte concentration and yield, without the use of probes. The future of this system will ensure increased platelet yields with new channel designs or protocol modifications.
authors.affiliation: COBE Laboratories Inc., Lakewood, Colo.
authors.forename: S G
authors.initials: SG
authors.lastname: Urdahl
mesh_terms: D000465:Algorithms; D001781:Blood Component Removal / Q000295:instrumentation*; D001782:Blood Donors; D001793:Blood Preservation / Q000295:instrumentation; D001803:Blood Transfusion; D001810:Blood Volume; D002951:Citrates / Q000008:administration & dosage; D019343:Citric Acid; D003201:Computers; D004867:Equipment Design; D006801:Humans; D010976:Platelet Count / Q000295:instrumentation; D017713:Platelet Transfusion; D010983:Plateletpheresis / Q000295:instrumentation*
chemical_list: D002951:Citrates; D019343:Citric Acid