Characterization of the branch site in lariat RNAs produced by splicing of mRNA precursors.
The branch site of lariat RNAs produced during the splicing of the first two late leader exons of adenovirus-2 has a structure of (formula; see text) There is a distinct complementarity between sequences preceding the adenosine at the branch site and the 5' terminus of the intervening sequence.
Konarska
M M
MM
Grabowski
P J
PJ
Padgett
R A
RA
Sharp
P A
PA
D000260:Adenoviruses, Human / Q000235:genetics; D001483:Base Sequence; D006367:HeLa Cells / Q000378:metabolism; D006801:Humans; D009690:Nucleic Acid Conformation; D009694:Nucleic Acid Precursors / Q000032:analysis*; D009841:Oligonucleotides / Q000032:analysis; D012313:RNA / Q000032:analysis*; D012322:RNA Precursors; D012326:RNA Splicing; D012333:RNA, Messenger / Q000032:analysis*; D012367:RNA, Viral / Q000032:analysis*; D012259:Ribonuclease, Pancreatic; D012261:Ribonucleoproteins / Q000378:metabolism; D017411:Ribonucleoproteins, Small Nuclear
D009694:Nucleic Acid Precursors; D009841:Oligonucleotides; D012322:RNA Precursors; D012333:RNA, Messenger; D012367:RNA, Viral; D012261:Ribonucleoproteins; D017411:Ribonucleoproteins, Small Nuclear; D012313:RNA; D012259:Ribonuclease, Pancreatic