[Infection by the HIV virus and transfusions. Study of 38 pediatric cases].
We report the cases of 38 children with transfusion-associated HIV infection: 18 hemophiliacs and 2 patients with Von Willebrand disease, 6 with hemoglobinopathies, 8 with malignant diseases or aplastic anemia, 2 transfused during neonatal period and 2 during a surgical operation. Two groups with a different prognosis were found: In group A [hemophilia and Von Willebrand disease (n = 20)] 17 patients were asymptomatic or only with lymphadenopathy; 3 reached stage IV and none died. In group B [Others (n = 14)] 2 patients were asymptomatic, 4 reached stage IV and 8 died, 4 of them directly from AIDS. The difference between both groups was statistically significant. Prognosis of HIV infection is particularly severe in patients with leukemia, malignant tumors and aplastic anemia.
Kone
I
I
Service d'Hématologie Pédiatrique, Groupe Hospitalier de la Timone, Marsielle.
Michel
G
G
Thuret
I
I
Siccardi
F
F
Vallee
D
D
Juhan
I
I
Perrimond
H
H
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000635:transmission*; D000293:Adolescent; D001803:Blood Transfusion; D002648:Child; D002675:Child, Preschool; D005260:Female; D006467:Hemophilia A / Q000150:complications; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D014842:von Willebrand Diseases / Q000150:complications
Contamination par le virus HIV et transfusions. Etude de 38 observations pédiatriques.