[Alkaline phosphatase in human lymphocytes. I. Cytochemical detection of alkaline phosphatase in normal human peripheral blood lymphocytes].
The present paper deals with a sensitive cytochemical method of identifying alkaline phosphatase (AP) in rosette-forming lymphocytes gained from the peripheral blood of healthy human beings. The percentage of AP-positive lymphocytes amounts to 5%, with all cells comprising B- and O-lymphocyte population and with T-lymphocytes being negative. In a group of healthy test persons, recently, however, having undergone various inflammatory processes or virus diseases, the number of AP-positive lymphocytes is significantly higher, from 41-73% in B- and O-lymphocytes and from 6-38% in T-lymphocytes. This observation indicates that AP in lymphocytes may have a clinical significance in reactive lymphoproliferative processes, which must be elucidated by further investigations.
Dikow
A
A
Meschkov
T
T
Radeva
M
M
Pfleiderer
G
G
D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood*; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000201:enzymology*; D008297:Male; D008722:Methods; D008875:Middle Aged; D012016:Reference Values
D000469:Alkaline Phosphatase
Die alkalische Phosphatase der Lymphozyten des Menschen. I. Zytochemischer Nachweis der alkalischen Phosphatase in den Lymphozyten aus dem peripheren Blut gesunder Menschen.