Microscopic polyarteritis: clinical features and treatment.
The clinical features, treatment and survival of 36 patients with microscopic polyarteritis diagnosed between 1957-1988 have been reviewed. All had a focal segmental necrotizing glomerulonephritis on renal biopsy with evidence of a small vessel vasculitis. Most had a prodromal illness of less than 1 month. Severity of renal disease varied from microscopic haematuria which has a good prognosis to acute oliguric renal failure which carries a high mortality. The prognosis of microscopic polyarteritis can be improved if the condition is recognized early and treated with steroids and cyclophosphamide.
Rodgers
H
H
Regional Renal Unit, General Infirmary Leeds, UK.
Guthrie
J A
JA
Brownjohn
A M
AM
Turney
J H
JH
D000328:Adult; D000368:Aged; D001167:Arteritis / Q000097:blood / Q000150:complications / Q000401:mortality / Q000628:therapy*; D002423:Cause of Death; D005260:Female; D005923:Glomerulosclerosis, Focal Segmental / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies