[Effect of fructose-1,6-diphosphate on the size of the necrotic area and course of the acute period of experimental myocardial infarction in rats].
The experiments on rats indicated that fructose-1,6-diphosphate substantially decreased the sizes of a necrotic zone, elevated myocardial ATP levels, reduced the edematization of lung tissue, shortened the duration of early postocclusive arrhythmias, and increased the latent period for their development. A dose-dependent cardioprotective effect was found in the preparation.
Sernov
L N
LN
Snegireva
G V
GV
Gatsura
V V
VV
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D004734:Energy Metabolism / Q000187:drug effects; D005635:Fructosediphosphates / Q000627:therapeutic use*; D006598:Hexosediphosphates / Q000627:therapeutic use*; D066298:In Vitro Techniques; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D009206:Myocardium / Q000378:metabolism / Q000473:pathology*; D009336:Necrosis; D051381:Rats
D005635:Fructosediphosphates; D006598:Hexosediphosphates; D000255:Adenosine Triphosphate; C029063:fructose-1,6-diphosphate
Vliianie fruktozo-1,6-difosfata na razmery zony nekroza i techenie ostrogo perioda éksperimenta'lnogo infarkta miokarda u krys.