S-100 protein in glands within decidua and cervical glands during early pregnancy.
Strong immunoreactivity with polyclonal S-100 protein antisera and monoclonal S-100 alpha subunit antiserum was found in glandular cells of the decidua basalis and cervical polyps during early pregnancy. Immunoreactive S-100 protein was negative in glandular cells of the endometrium and cervix of nonpregnant women. It was also negative in endometrial hyperplasia and endometrial carcinoma. While the function of S-100 protein is not known, a relationship between humoral factors related to pregnancy and expression of S-100 protein gene is suggested by the results of this study.
Nakamura
Y
Y
Department of Pathology, St Mary's Hospital, Kurume, Japan.
Moritsuka
Y
Y
Ohta
Y
Y
Itoh
S
S
Haratake
A
A
Kage
M
M
Kawano
K
K
D002584:Cervix Uteri / Q000032:analysis* / Q000166:cytology; D003656:Decidua / Q000032:analysis* / Q000166:cytology; D004717:Endometrium / Q000032:analysis; D005260:Female; D006801:Humans; D011247:Pregnancy / Q000378:metabolism*; D009418:S100 Proteins / Q000032:analysis*
D009418:S100 Proteins