title: Comparison of trioxsalen bath and oral methoxsalen PUVA in psoriasis.
abstract: Fifty patients with chronic plaque psoriasis were treated with trioxsalen bath PUVA and 43 patients with oral methoxsalen PUVA. The two treatment regimens gave similar results; 75% and 77% of the patients had excellent or good clearing and a follow-up of one year revealed relapses in 61% and 58% of the patients, respectively. The cumulative UVA dose remained significantly lower in bath PUVA (mean 23.5 J/cm2) than in oral PUVA (mean 131 J/cm2). Nausea and headache occurred in 21% of the patients receiving oral PUVA but in none in the bath PUVA group. Local side-effects were found in 30% of the patients receiving bath PUVA and in 17% of the patients in the oral PUVA group.
authors.forename: K
authors.initials: K
authors.lastname: Turjanmaa
authors.forename: H
authors.initials: H
authors.lastname: Salo
authors.forename: T
authors.initials: T
authors.lastname: Reunala
mesh_terms: D000328:Adult; D001494:Baths; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D011564:Furocoumarins / Q000627:therapeutic use*; D006801:Humans; D011701:PUVA Therapy; D010778:Photochemotherapy; D011565:Psoriasis / Q000188:drug therapy*; D014307:Trioxsalen / Q000627:therapeutic use*
chemical_list: D011564:Furocoumarins; D014307:Trioxsalen