title: [Evolution of Alu repeats: dynamics of distribution in genome].
abstract: A mathematical model of evolutionary dynamics of Alu repeats' number in the human genome has been worked out. The model permitted us to observe the dynamics of propagation of Alu repeats within the genome and to evaluate such important parameters of the process mentioned as the rates of transposition (insertion of new copies into the genome) and excision of repeats. The peculiarities of the control of Alu repeats' number in the genome have been discussed, based on the data obtained.
authors.forename: I A
authors.initials: IA
authors.lastname: Shakhmuradov
authors.forename: V V
authors.initials: VV
authors.lastname: Kapitonov
authors.forename: N A
authors.initials: NA
authors.lastname: Kolchanov
authors.forename: L V
authors.initials: LV
authors.lastname: Omel'ianchuk
mesh_terms: D015894:Genome, Human; D006801:Humans; D008433:Mathematics; D008957:Models, Genetic; D012091:Repetitive Sequences, Nucleic Acid
vernacular_title: Evoliutsiia povtorov Alu: dinamika rasprostraneniia v genome.