title: Commingling in the distributions of immunoglobulin levels.
abstract: Commingling in the distributions of five immunoglobulins from a Canadian sample of 810 Caucasians and IgE from a US sample of 935 Caucasians was investigated. For both the Canadian and US samples significant commingling was found in the child's but not the adult's IgE distribution. Contrary to expectations based upon the major gene hypothesis for IgM, we found no evidence for commingling in the IgM distribution. Finally, the distributions of IgA, IgD and IgG all evidenced significant commingling that may be the result of a single gene effect or the operation of a discrete environmental effect.
authors.affiliation: Department of Psychology, University of Minnesota, Minn.
authors.forename: M
authors.initials: M
authors.lastname: McGue
authors.forename: J W
authors.initials: JW
authors.lastname: Gerrard
authors.forename: M D
authors.initials: MD
authors.lastname: Lebowitz
authors.forename: D C
authors.initials: DC
authors.lastname: Rao
mesh_terms: D000328:Adult; D000367:Age Factors; D002648:Child; D005828:Genetics, Population; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis / Q000235:genetics*; D012737:Sex Factors
chemical_list: D007136:Immunoglobulins