title: Minimizing and measuring lens dose when giving cranial irradiation.
abstract: Three different techniques of administering cranial irradiation were used to determine the dose to the lens as measured in the Rando phantom. The techniques employed were as follows: (1) the central axis of the radiation beam was placed at the thickest portion of the cranium; (2) the central axis of the radiation beam was placed at the lateral orbital rim (bony canthus); (3) the central axis of the radiation beam was placed at the thickest portion of the cranium but with the beam angled 5 degrees posteriorly away from the eye. Thermal luminescent dosimeters (TLD) were placed in a phantom, at a point determined from a life-sized anatomical section of the plane through the midsection of the eye, to be at the location of the posterior capsule of the lens. In addition, TLDs were placed on the outer surface of the phantom head, directly lateral to the location determined to be where the lens would lie. With equally weighted lateral opposed beams, delivering a midplane dose of 200 cGy, the TLDs at the point of the lens measured 21, 9.9 and 10.6% of the midplane doses from the three techniques respectively. TLDs placed directly lateral to the lens on the surface of the phantom head gave an approximation of the lens dose, particularly when techniques 2 and 3 were used. Isodose curve generated by a General Electric treatment planning computer gave lens doses similar to those of the phantom data for each of the three different radiotherapy techniques. Cranial irradiation should be carried out by either technique 2 or technique 3 to minimize radiation dose to the lens.
authors.affiliation: Department of Radiation Oncology, Stanford University School of Medicine 94305.
authors.forename: S Y
authors.initials: SY
authors.lastname: Woo
authors.forename: S S
authors.initials: SS
authors.lastname: Donaldson
authors.forename: R J
authors.initials: RJ
authors.lastname: Heck
authors.forename: K L
authors.initials: KL
authors.lastname: Nielson
authors.forename: C
authors.initials: C
authors.lastname: Shostak
mesh_terms: D001932:Brain Neoplasms / Q000517:prevention & control*; D002386:Cataract / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D007908:Lens, Crystalline / Q000528:radiation effects*; D008961:Models, Structural; D011832:Radiation Injuries / Q000517:prevention & control*; D011879:Radiotherapy Dosage; D011881:Radiotherapy, Computer-Assisted