title: [The role of endogenous enkephalins in the regulation of bone marrow hematopoiesis in stress].
abstract: A study was made of the effect of the enkephalinase inhibitor D-phenylalanine on hematopoiesis during the immobilization stress. The long-term treatment with D-phenylalanine before the immobilization stress resulted in a significant increase of plasma ley-enkephalin in mice during the first day after exposure. Later the inhibition of bone marrow hyperplasia was recorded. There were no changes in hematopoiesis provided D-phenylalanine was injected after the immobilization. It is suggested that endogenous enkephalins may take part in the regulation of hematopoiesis at the early period of the stress reaction formation.
authors.forename: E D
authors.initials: ED
authors.lastname: Go'ldberg
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Zakharova
authors.forename: A M
authors.initials: AM
authors.lastname: Dygaĭ
authors.forename: M M
authors.initials: MM
authors.lastname: Kozlovskaia
authors.forename: Iu B
authors.initials: IuB
authors.lastname: Lishmanov
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000473:pathology*; D004743:Enkephalin, Leucine / Q000502:physiology*; D006410:Hematopoiesis / Q000502:physiology*; D006412:Hematopoietic Stem Cells / Q000502:physiology*; D008297:Male; D051379:Mice; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000097:blood / Q000473:pathology / Q000503:physiopathology*
chemical_list: D004743:Enkephalin, Leucine
vernacular_title: Ob uchastii éndogennykh énkefalinov v reguliatsii kostno- mozgovogo krovetvoreniia pri stresse.