Calbindins D-9kDa and -28kDa and enamel secretion in vitamin D-deficient and control rats.
The present study focuses on the ultrastructure of enamel organ cells and the immunolocalization of calbindins D-9kDa and -28kDa during enamel secretion in Vitamin D-deficient rats. Vitamin D-deficiency disturbed the deposition of the layer of inner enamel and depleted the calbindins-content of ameloblasts. These data raise the possibility of a direct action of Vitamin D on the physiology of ameloblasts through ionic calcium homeostasis.
Berdal
A
A
U 120 INSERM Le Vésinet France.
Balmain
N
N
Thomasset
M
M
Brehier
A
A
Hotton
D
D
Cuisinier-Gleizes
P
P
Mathieu
H
H
D000565:Ameloblasts / Q000378:metabolism; D000818:Animals; D064026:Calbindins; D003743:Dental Enamel / Q000378:metabolism* / Q000648:ultrastructure; D007150:Immunohistochemistry; D008854:Microscopy, Electron; D008970:Molecular Weight; D051381:Rats; D064030:S100 Calcium Binding Protein G / Q000378:metabolism*; D014808:Vitamin D Deficiency / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology*
D064026:Calbindins; D064030:S100 Calcium Binding Protein G