title: Synthesis and biological activity of a new squaric acid-formylmethionine peptide conjugate.
abstract: A new squaric acid-formylmethionine peptide has been synthesized. In view of its biological properties to induce lysosome release and to inhibit glyoxalase, this compound may be of pharmacologic value.
authors.affiliation: Laboratoire de Chimie Biomoléculaire, Faculté des Sciences de Luminy, Marseille.
authors.forename: J L
authors.initials: JL
authors.lastname: Kraus
authors.forename: M
authors.initials: M
authors.lastname: Castaing
mesh_terms: D055598:Chemical Phenomena; D002621:Chemistry; D002855:Chromatography, Thin Layer; D003503:Cyclobutanes / Q000138:chemical synthesis* / Q000494:pharmacology; D006801:Humans; D007791:Lactoylglutathione Lyase / Q000037:antagonists & inhibitors*; D008190:Lyases / Q000037:antagonists & inhibitors*; D008247:Lysosomes / Q000378:metabolism*; D009240:N-Formylmethionine Leucyl-Phenylalanine / Q000138:chemical synthesis / Q000494:pharmacology / Q000031:analogs & derivatives; D013056:Spectrophotometry, Ultraviolet
chemical_list: D003503:Cyclobutanes; C061883:squaric acid N-formylmethionyl-leucyl-phenylalanine methyl ester peptide conjugate; D009240:N-Formylmethionine Leucyl-Phenylalanine; D008190:Lyases; D007791:Lactoylglutathione Lyase