[Cathepsin H activity in the human brain and human brain neoplasms].
The human brain cathepsin H is shown to be a specific cysteine aminopeptidase with the optimum activity at pH 6.0. Human brain tumours of neuroectodermal (astrocytomas and glioblastomas) and epithelial (meningiomas) origin were used to study the cathepsin H activity in the malignant brain tissue. A significant increase in the aminopeptidase cathepsin H activity was found in malignant human brain tumours as compared to benign tumours and normal brain tissues.
Chernaia
V I
VI
Reva
A D
AD
D001921:Brain / Q000201:enzymology*; D001932:Brain Neoplasms / Q000201:enzymology*; D056655:Cathepsin H; D002403:Cathepsins / Q000378:metabolism*; D003546:Cysteine Endopeptidases; D006801:Humans; D006863:Hydrogen-Ion Concentration
D002403:Cathepsins; D003546:Cysteine Endopeptidases; C534126:CTSH protein, human; D056655:Cathepsin H
Aktivnost' katepsina H v mozge i opukholiakh mozga cheloveka.