title: Malignant melanoma lately diagnosed.
abstract: To assess the clinical impression that patients in Dublin were presenting with late, deep, poor prognosis lesions, a 10 year retrospective review of patients with malignant melanoma was performed. The pathological data on 186 patients was examined and clinical follow-up obtained on 151 of these (80%). The mean period of follow-up was 35 months. Females predominated in a ratio of 3:1. Incidence figures for the two five year periods (1976-80) and (1981-85) indicated a rise in the latter period of over 100%. There was a marked delay in presentation after the onset of symptoms i.e. new pigmented lesions or changes in pre-existing lesions (mean = 21 months). Only 45% of lesions were less than 1.5mm in depth. Females presented with a higher percentage of good prognosis lesions reflected in a superior five year survival figure of 70% compared with 43% for males. The results of this study suggest an increase in incidence and mortality from malignant melanoma in this country. Patients appear to be unaware of the significance of pigmented lesions, presenting late with deep poor prognosis tumours.
authors.forename: G M
authors.initials: GM
authors.lastname: Lennon
authors.forename: M
authors.initials: M
authors.lastname: Griffin
authors.forename: D S
authors.initials: DS
authors.lastname: O'Briain
authors.forename: M
authors.initials: M
authors.lastname: Cassidy
authors.forename: M
authors.initials: M
authors.lastname: Caldwell
authors.forename: M
authors.initials: M
authors.lastname: Young
authors.forename: W A
authors.initials: WA
authors.lastname: Tanner
authors.forename: F B
authors.initials: FB
authors.lastname: Keane
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007494:Ireland / Q000453:epidemiology; D008297:Male; D008545:Melanoma / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality; D008875:Middle Aged; D012878:Skin Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality