[Effects of inhalation anesthetics on hepatic ATP and L/P ratio in the rat subjected to hemorrhagic shock].
Both anesthetics and hemorrhage may affect the hepatic energy metabolism. The effects of inhalation anesthetics (halothane, enflurane and isoflurane) on hepatic ATP level and L/P ratio were evaluated in rat under hemorrhagic shock. There was no significant difference in the hepatic ATP levels among 4 groups. However the L/P ratio in 3 inhalation anesthetic groups was significantly lower than that in control group. These results suggest that inhalation anesthetics may improve the hepatic energy metabolism during hemorrhagic shock.
Kashimoto
S
S
Nonaka
A
A
Kume
M
M
Kumazawa
T
T
D000818:Animals; D004734:Energy Metabolism / Q000187:drug effects; D004737:Enflurane / Q000494:pharmacology*; D006221:Halothane / Q000494:pharmacology*; D007530:Isoflurane / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012771:Shock, Hemorrhagic / Q000378:metabolism*
D004737:Enflurane; D007530:Isoflurane; D006221:Halothane