title: Personality and response to tricyclic antidepressants in depressed patients.
abstract: Several studies have shown that disturbances of personality are poor predictors of response to antidepressants. None of these studies, however, has used personality measures similar to the DSM-III. We evaluated the relationship between antidepressant response and personality scores obtained on the Millon Clinical Multiaxial Inventory, which provides personality measures congruent with DSM-III. Personality features such as assertiveness, independence, and competitiveness distinguished responders from nonresponders. However, the frequency of personality disorder diagnoses did not differ between responders and nonresponders.
authors.affiliation: Department of Psychiatry, St. Michael's Hospital, Toronto, Ontario, Canada.
authors.forename: R T
authors.initials: RT
authors.lastname: Joffe
authors.forename: J J
authors.initials: JJ
authors.lastname: Regan
mesh_terms: D000328:Adult; D000929:Antidepressive Agents, Tricyclic / Q000008:administration & dosage / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010551:Personality; D010554:Personality Disorders / Q000150:complications; D010555:Personality Inventory; D013997:Time Factors
chemical_list: D000929:Antidepressive Agents, Tricyclic