Flavones and flavonol glycosides from Eupatorium cannabinum L.
The 6-methoxyflavones hispidulin and eupafolin have been identified for the first time from the aerial parts of Eupatorium cannabinum L. The presence of the previously known flavonol glycosides astragalin, kaempferol-3-rutinoside, hyperoside, isoquercitrin and rutin could be confirmed. Hispidulin, eupafolin and rutin were screened for cytotoxicity in vitro.
Elema
E T
ET
Department of Pharmacognosy, University of Groningen, The Netherlands.
Schripsema
J
J
Malingré
T M
TM
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D002852:Chromatography, Ion Exchange; D002855:Chromatography, Thin Layer; D005419:Flavonoids / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000302:isolation & purification* / Q000494:pharmacology; D013058:Mass Spectrometry; D010946:Plants, Medicinal / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet
D000972:Antineoplastic Agents, Phytogenic; D005419:Flavonoids; D006027:Glycosides