title: Altemicidin, a new acaricidal and antitumor substance. II. Structure determination.
abstract: The structure of altemicidin, a new acaricidal and antitumor agent, was determined to be (1R,2S,3aR,7aS)-4-carbamoyl-2-hydroxy-6-methyl-1-(sulfamo ylacetamido)-2,3,3a,6, 7,7a-hexahydro-6-azaindene-1-carboxylic acid by a combination of spectroscopic and X-ray crystallographic analysis of its derivatives. Altemicidin is a monoterpene alkaloid.
authors.affiliation: Institute of Microbial Chemistry, Tokyo, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Takahashi
authors.forename: D
authors.initials: D
authors.lastname: Ikeda
authors.forename: H
authors.initials: H
authors.lastname: Nakamura
authors.forename: H
authors.initials: H
authors.lastname: Naganawa
authors.forename: S
authors.initials: S
authors.lastname: Kurasawa
authors.forename: Y
authors.initials: Y
authors.lastname: Okami
authors.forename: T
authors.initials: T
authors.lastname: Takeuchi
authors.lastname: IitakaY
mesh_terms: D000470:Alkaloids / Q000032:analysis; D000903:Antibiotics, Antineoplastic / Q000032:analysis; D003461:Crystallography; D007306:Insecticides / Q000032:analysis; D016018:Least-Squares Analysis; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D008958:Models, Molecular; D015394:Molecular Structure; D011725:Pyridines; D013457:Sulfur Compounds
chemical_list: D000470:Alkaloids; D000903:Antibiotics, Antineoplastic; D007306:Insecticides; D011725:Pyridines; D013457:Sulfur Compounds; C061865:altemicidin