title: Postprandial gallbladder filling: relation to gastrointestinal motility.
abstract: A technique of combined hepatobiliary scintigraphy and gastrointestinal motility recordings was used to study the relationship between gallbladder dynamics and gastrointestinal motility recordings in the postprandial state in eight healthy male volunteers. In all, a fed-like motility pattern was observed after ingestion of a standard meal, and all activity from the HIDA-scintigraphy was diverted to the duodenum. Gallbladder radioactivity on the scintigram was not seen until 145-249 (median, 180) min after ingestion, except for two cases in which an early and transient activity was seen. Together with increasing gallbladder radioactivity characteristic changes in duodenal motility occurred. In five subjects a decrease in motility index was encountered with a motility curve resembling phase I of the interdigestive migrating motor complex. In one subject it was associated with the appearance of a phase-III complex, and in two subjects it occurred without any changes in motility index.
authors.affiliation: Dept. of Surgical Gastroenterology, Odense University Hospital, Denmark.
authors.forename: N
authors.initials: N
authors.lastname: Qvist
authors.forename: E
authors.initials: E
authors.lastname: Oster-Jørgensen
authors.forename: L
authors.initials: L
authors.lastname: Rasmussen
authors.forename: C
authors.initials: C
authors.lastname: Hovendal
authors.forename: S A
authors.initials: SA
authors.lastname: Pedersen
mesh_terms: D000328:Adult; D001646:Bile / Q000502:physiology*; D005704:Gallbladder / Q000000981:diagnostic imaging / Q000502:physiology*; D005769:Gastrointestinal Motility; D006801:Humans; D007098:Imino Acids; D008297:Male; D008365:Manometry; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D019780:Technetium Tc 99m Lidofenin
chemical_list: D007098:Imino Acids; D015609:Organotechnetium Compounds; D019780:Technetium Tc 99m Lidofenin