Successful use of clozapine in a patient with a history of neuroleptic malignant syndrome.
Reinstitution of antipsychotic medication is problematic in patients with a history of neuroleptic malignant syndrome (NMS). In this case, a patient with a history of probable neuroleptic malignant syndrome caused by administration, as single agents, of haloperidol, molindone, and lithium was later treated successfully with the novel antipsychotic clozapine. The propensity of various antipsychotic agents to cause NMS is discussed.
Stoudemire
A
A
Medical Psychiatry Unit, Emory University Hospital, Atlanta, Georgia.
Clayton
L
L
D000203:Activities of Daily Living / Q000523:psychology; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003024:Clozapine / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000188:drug therapy* / Q000523:psychology; D009459:Neuroleptic Malignant Syndrome / Q000188:drug therapy* / Q000523:psychology; D012008:Recurrence; D012560:Schizophrenia, Catatonic / Q000188:drug therapy* / Q000523:psychology
D014150:Antipsychotic Agents; D003024:Clozapine