[Tumor markers and endocrinologic aspects in intracranial germinoma].
This report outlines the endocrine abnormalities associated with intracranial germinoma in childhood. The presence of special tumoral markers as alpha 1-fetoprotein and beta-HCG could be of diagnostic value and is important in respect to therapy control. However the reported case shows that despite known radiosensitivity and appropriate radiotherapy localized tumor relapse may arise soon after treatment.
Andler
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W
Horstmann
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W
Distelmeier
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PM
D000293:Adolescent; D000951:Antigens, Neoplasm / Q000032:analysis*; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000532:radiotherapy; D006063:Chorionic Gonadotropin / Q000097:blood; D004407:Dysgerminoma / Q000175:diagnosis* / Q000532:radiotherapy; D005640:Follicle Stimulating Hormone / Q000097:blood; D006728:Hormones / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D010870:Pineal Gland / Q000528:radiation effects; D011388:Prolactin / Q000097:blood; D013739:Testosterone / Q000097:blood; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D000509:alpha-Fetoproteins / Q000378:metabolism
D000951:Antigens, Neoplasm; D006063:Chorionic Gonadotropin; D006728:Hormones; D000509:alpha-Fetoproteins; D013739:Testosterone; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin; D013974:Thyroxine; D006854:Hydrocortisone
Tumormarker und endokrinologische Aspekte beim intrakraniellen Germinom.