title: Molecular cloning of the Rauscher murine leukemia virus. Disease spectrum and integration pattern.
abstract: After transfection of NIH 3T3 cells with DNA from molecularly cloned Rauscher MuLV, virus was isolated which showed a disease spectrum comparable to that of R-MuLV cloned biologically by endpoint dilution. In both cases sites of proviral integration vary from 2-5 per leukemic tissue and occur apparently at random.
authors.affiliation: Department of Pathology, Faculty of Medicine, Erasmus University Rotterdam, The Netherlands.
authors.forename: M J
authors.initials: MJ
authors.lastname: van der Feltz
authors.forename: M E
authors.initials: ME
authors.lastname: Kranendonk-Odijk
authors.forename: E H
authors.initials: EH
authors.lastname: Rhijnsburger
authors.forename: J
authors.initials: J
authors.lastname: Stark
authors.forename: K
authors.initials: K
authors.lastname: Stoker
authors.forename: N J
authors.initials: NJ
authors.lastname: de Both
mesh_terms: D000818:Animals; D015139:Blotting, Southern; D002460:Cell Line; D003001:Cloning, Molecular; D004279:DNA, Viral / Q000235:genetics; D005814:Genes, Viral; D007942:Leukemia, Experimental / Q000382:microbiology; D051379:Mice; D008807:Mice, Inbred BALB C; D011533:Proviruses / Q000235:genetics / Q000378:metabolism; D011925:Rauscher Virus / Q000235:genetics* / Q000472:pathogenicity; D015183:Restriction Mapping; D014162:Transfection
chemical_list: D004279:DNA, Viral