title: [Initiation of RNA synthesis in isolated rat liver nuclei].
abstract: Isolated rat liver nuclei were incubated under conditions when RNA polymerase I or RNA polymerase II was preferentially active. It was shown that [gamma-32P] ATP and [gamma-32P] GTP were incorporated into phenol extractable, TCA-precipitable material. RNase, actinomycin D, heparin and, in the case of RNA-polymerase II, alpha-amanitine inhibited precursor incorporation. These data are interpreted as evidence in favour of the initiation of RNA synthesis in isolated rat liver nuclei.
authors.forename: A V
authors.initials: AV
authors.lastname: Glebov
authors.forename: A P
authors.initials: AP
authors.lastname: Kozlov
authors.forename: A Z
authors.initials: AZ
authors.lastname: Pliusnin
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism; D002474:Cell-Free System; D003609:Dactinomycin / Q000494:pharmacology; D006160:Guanosine Triphosphate / Q000378:metabolism; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism*; D008297:Male; D012313:RNA / Q000096:biosynthesis*; D012318:RNA Polymerase I / Q000378:metabolism; D012319:RNA Polymerase II / Q000378:metabolism; D051381:Rats; D014158:Transcription, Genetic
chemical_list: D003609:Dactinomycin; D012313:RNA; D006160:Guanosine Triphosphate; D000255:Adenosine Triphosphate; D012319:RNA Polymerase II; D012318:RNA Polymerase I
vernacular_title: Initsiatsiia sinteza RNK v vydelennykh iadrakh pecheni krysy.