Anti-inflammatory activity of some Iraqi plants using intact rats.
Five plants (Myrtus communis, Apium graveolens, Matricaria chamomilla, Withania somnifera and Achillea santolina) grown in Iraq were assessed for their anti-inflammatory activity on intact rats by measuring the suppression of carrageenan-induced paw edema produced by 1/10 of the intraperitoneal LD50 doses for the respective 80% ethanol extracts. Acetylsalicylic acid was used as the standard drug. Results showed that the plants possessed varying degrees of anti-inflammatory activity and were classified in the following descending order of activity: W. somnifera greater than A. graveolens greater than A. santolina greater than M. chamomilla greater than M. communis.
Al-Hindawi
M K
MK
Biological Research Centre, Scientific Research Council, Jadiriyah, Baghdad, Iraqu.
Al-Deen
I H
IH
Nabi
M H
MH
Ismail
M A
MA
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D002351:Carrageenan; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D005260:Female; D007493:Iraq; D007928:Lethal Dose 50; D008297:Male; D010946:Plants, Medicinal; D010991:Plethysmography; D051381:Rats; D011919:Rats, Inbred Strains
D000893:Anti-Inflammatory Agents; D002351:Carrageenan