title: RNA polymerase heterogeneity in Streptomyces coelicolor.
abstract: Two forms of RNA polymerase holoenzyme have been identified in the filamentous differentiating bacterium Streptomyces coelicolor. They contain different species of sigma factor and are distinguishable by their ability to recognize different promoter classes. These and other holoenzyme forms may in part determine the selective expression of different gene sets in this morphologically-complex bacterium.
authors.forename: J
authors.initials: J
authors.lastname: Westpheling
authors.forename: M
authors.initials: M
authors.lastname: Ranes
authors.forename: R
authors.initials: R
authors.lastname: Losick
mesh_terms: D001483:Base Sequence; D002454:Cell Differentiation; D004269:DNA, Bacterial / Q000235:genetics; D012321:DNA-Directed RNA Polymerases / Q000235:genetics*; D005786:Gene Expression Regulation; D011401:Promoter Regions, Genetic; D012329:RNA, Bacterial / Q000235:genetics; D012808:Sigma Factor / Q000235:genetics*; D013302:Streptomyces / Q000201:enzymology* / Q000235:genetics; D014157:Transcription Factors / Q000235:genetics*; D014158:Transcription, Genetic
chemical_list: D004269:DNA, Bacterial; D012329:RNA, Bacterial; D012808:Sigma Factor; D014157:Transcription Factors; D012321:DNA-Directed RNA Polymerases