[Radioprotective properties of a Co(III) biocomplex].
In experiments with rats and mice irradiated with doses of 5 and 8.5 Gy respectively, the radioprotective properties of a coordination combination Co(III) with bioactive ligands have been investigated by the results of the hematological analysis, the indices of erythrocyte and leucocyte electric conductivity, average life, survival rate, and beta coefficient showing a probability of protecting the organism against fatal effect of ionizing radiation. The preparation has either therapeutic or protective action depending on the animal species and radiation dose.
Islamov
Iu N
IuN
Akbarov
A B
AB
Khakimov
P A
PA
Shadieva
N Kh
NKh
Islamov
M N
MN
D000818:Animals; D003035:Cobalt / Q000627:therapeutic use* / Q000633:toxicity; D004906:Erythrocyte Count; D006454:Hemoglobins / Q000032:analysis; D007958:Leukocyte Count; D008297:Male; D051379:Mice; D009942:Organometallic Compounds / Q000627:therapeutic use* / Q000633:toxicity; D011833:Radiation Injuries, Experimental / Q000097:blood / Q000188:drug therapy / Q000517:prevention & control; D011837:Radiation-Protective Agents / Q000627:therapeutic use*; D051381:Rats
D006454:Hemoglobins; D009942:Organometallic Compounds; D011837:Radiation-Protective Agents; D003035:Cobalt
Izuchenie radiozashchitnykh svoĭstv biokompleksa Co(III).