[Pathogenetic significance of lipid peroxidation in damage of the proximal segment of the nephron in acute Masugi's nephritis].
During the acute experimental nephritis a decrease of reabsorption by proximal tubules is combined with the activation of the lipid peroxidation into the renal cortex without changes in the activation of lysosomal enzyme of acid phosphatase and cathepsin D. Ionol, an inhibitor of oxygen products, exerts a protective action on the renal function and reabsorption by proximal tubules, decreasing concentration of the malondialdehyde into the renal cortex.
Rogovoĭ
Iu E
IuE
Gozhenko
A I
AI
D058186:Acute Kidney Injury / Q000209:etiology*; D000818:Animals; D005921:Glomerulonephritis / Q000150:complications / Q000378:metabolism*; D007683:Kidney Tubular Necrosis, Acute / Q000209:etiology*; D007687:Kidney Tubules, Proximal / Q000378:metabolism*; D015227:Lipid Peroxidation; D008297:Male; D051381:Rats
Patogeneticheskoe znachenie perekisnogo okisleniia lipidov v povrezhdenii proksima'lnogo otdela nefrona pri ostrom nefrite Lindemana-Mazugi.