Fluoxetine added to non-MAOI antidepressants converts nonresponders to responders: a preliminary report.
Thirty depressed outpatients poorly responsive to various non-MAOI antidepressants had fluoxetine added to their regimens. Retrospective analysis revealed that 26 (86.7%) of the patients improved. Non-MAOI antidepressant treatment was withdrawn for 12 of the 26 responders; of these, 8 relapsed on fluoxetine treatment alone but recovered when treatment with the discontinued non-MAOI agent was restarted.
Weilburg
J B
JB
Clinical Psychopharmacology Unit, Massachusetts General Hospital, Boston 02114.
Rosenbaum
J F
JF
Biederman
J
J
Sachs
G S
GS
Pollack
M H
MH
Kelly
K
K
D000328:Adult; D000368:Aged; D000928:Antidepressive Agents / Q000627:therapeutic use*; D001714:Bipolar Disorder / Q000188:drug therapy*; D003866:Depressive Disorder / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D005473:Fluoxetine / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
D000928:Antidepressive Agents; D005473:Fluoxetine