[Morphological features of experimental transient endolymphatic hydrops].
This paper describes a method for simulating transient endolymphatic hydrops based on the generation of vasomotor disorders in the labyrinthine artery area. The method is based on a deep short-term chloroethyl freezing of the lateral surface of the animal surface in the projection of the spinal artery. In histological terms, hydrops is characterized by two factors: vascular lesions (hyperemia of the vascular stripe, venous congestion) and changes in physico-chemical parameters of labyrinthine fluids (edema of cell elements of the labyrinth, membrane deformation, precipitation of the granular-reticular residue in the endo- and perilymphatic spaces). This method can be used to study the origin of endolymphatic hydrops during Ménière's disease, to develop new approaches and to give a pathogenetic substantiation of existing approaches to the treatment of Ménière's disease.
Pomukhina
A N
AN
Kiselev
V V
VV
D000818:Animals; D003051:Cochlea / Q000473:pathology; D004487:Edema / Q000473:pathology*; D004710:Endolymph; D007759:Labyrinth Diseases / Q000473:pathology*; D007761:Labyrinthine Fluids; D008575:Meniere Disease / Q000473:pathology; D009925:Organ of Corti / Q000473:pathology; D051381:Rats; D013997:Time Factors
Morfologicheskaia kharakteristika éksperimental'nogo prekhodiashchegoéndolimfaticheskogo gidropsa.