Coexistence of calcitonin gene-related peptide and substance P-like peptide in single cells of the trigeminal ganglion of the rat: immunohistochemical analysis.
The localization of calcitonin gene-related peptide (CGRP) and substance P (SP) in the rat trigeminal ganglion was examined by means of the indirect immunofluorescent method. About 40% of neurons in the ganglion contained CGRP-like immunoreactivity (CGRPI), while about 20% of neurons showed SP-like immunoreactivity (SPI). In serial sections, nearly all the SPI neurons contained CGRPI.
Lee
Y
Y
Kawai
Y
Y
Shiosaka
S
S
Takami
K
K
Kiyama
H
H
Hillyard
C J
CJ
Girgis
S
S
MacIntyre
I
I
Emson
P C
PC
Tohyama
M
M
D000818:Animals; D015740:Calcitonin Gene-Related Peptide; D005455:Fluorescent Antibody Technique; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D051381:Rats; D013373:Substance P / Q000378:metabolism*; D012668:Trigeminal Ganglion / Q000378:metabolism*; D014276:Trigeminal Nerve / Q000378:metabolism*; D014279:Trigeminal Nucleus, Spinal
D009419:Nerve Tissue Proteins; D013373:Substance P; D015740:Calcitonin Gene-Related Peptide