title: Lumbar cerebrospinal fluid homovanillic acid concentrations are higher in female than male non-human primates.
abstract: Concentrations of homovanillic acid and 5-hydroxyindoleacetic acid were determined in lumbar cerebrospinal fluid from intact male and female Macaca nemestrina. Concentrations of homovanillic acid, but not 5-hydroxyindoleacetic acid were significantly higher in the females under baseline conditions. Following probenecid treatment, 5-hydroxyindoleacetic acid concentrations were significantly elevated over baseline conditions in both sexes although only homovanillic acid concentrations were significantly higher in the female monkeys.
authors.forename: R F
authors.initials: RF
authors.lastname: Seegal
mesh_terms: D000818:Animals; D005260:Female; D006719:Homovanillic Acid / Q000134:cerebrospinal fluid*; D006897:Hydroxyindoleacetic Acid / Q000134:cerebrospinal fluid; D008254:Macaca nemestrina; D008297:Male; D010648:Phenylacetates / Q000134:cerebrospinal fluid*; D011339:Probenecid / Q000494:pharmacology; D012727:Sex Characteristics
chemical_list: D010648:Phenylacetates; D006897:Hydroxyindoleacetic Acid; D011339:Probenecid; D006719:Homovanillic Acid