[Characteristics of the composition of fluorescent lipopigments of the liver and brain in rats of various ages].
Spectral characteristics of the lipid liver and brain extracts were studied in experiments on rats of different age (1, 3, 12, 24 months). The aim of the experiments was to study age peculiarities of the lipopigments composition by means of thin-layer and liquid chromatography. Different fractions of lipids which differ in spectral absorption and fluorescence were extracted. Proceeding from the results obtained certain conclusions may be derived: the processes of structural recombination of the whole lipid constituents are accompanied by the age accumulation of lipofuscin; the process of accumulation of lipofuscin is not monotonous and has pronounced age peculiarities; the formation of the lipid-pigment complex is tissue-specific.
Paranich
A V
AV
Chaĭkina
L A
LA
Ionov
I A
IA
D000367:Age Factors; D000818:Animals; D001923:Brain Chemistry; D002853:Chromatography, Liquid / Q000379:methods; D002855:Chromatography, Thin Layer / Q000379:methods; D005260:Female; D005453:Fluorescence; D008062:Lipofuscin / Q000032:analysis*; D008099:Liver / Q000032:analysis*; D010860:Pigments, Biological / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains; D014020:Tissue Extracts / Q000032:analysis*
D008062:Lipofuscin; D010860:Pigments, Biological; D014020:Tissue Extracts
Osobennosti sostava fliuorestsiruiushchikh lipopigmentov pecheni i mozga krys raznogo vozrasta.