[Grading and prognostic rating of oral carcinomas based on their cloning potential in vitro. Guidelines for clinical antioncogram interpretation].
Malignancies of the oral cavity are not an entity in terms of their clonal growth potential. The antioncogram which is used within the individual treatment concept against the carcinoma may be employed to determine whether the tumor of this patient has a high or low cloning potential. This parameter of differentiated cloning is an independent tumor characteristic for the purpose of grading and is closely related to clinical course and prognosis of the patient. Patients with highly cloning malignancies have a significantly shorter life expectancy than patients with the same risk factors suffering from carcinomas with a low cloning potential.
Metelmann
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HR
D006801:Humans; D009062:Mouth Neoplasms / Q000145:classification*; D012307:Risk Factors
Grading und prognostische Bewertung von Mundhöhlenkarzinomen auf der Grundlage ihrer Klonierungsfähigketi in vitro. Leitsätze zur klinischen Antionkogramm-Interpretation.