[A 2-component tumor of the breast with carcinoid syndrome].
The structures of a well-differentiated apudoma were combined with the foci of colloid carcinoma in a mammary gland tumour described. Two types of cells with argyrophil grains are distinguished depending on the argyrophil grain size, localization in the tumour cell cytoplasm and the ability to react with hormonal antisera. The first type cells correspond to the true apudocytes and produce serotonin and beta-endorphine. The smallest silver granules imitate the endocrine granules in the cells of the second type. The peculiar feature of this observation is in its clinical manifestations typical for the carcinoid syndrome.
Serezhin
B S
BS
D001078:APUD Cells / Q000473:pathology; D002288:Adenocarcinoma, Mucinous / Q000473:pathology*; D001079:Apudoma / Q000473:pathology*; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008303:Malignant Carcinoid Syndrome / Q000473:pathology*; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology*
Dvukhkomponentnaia opukhol' molochnoĭ zhelezy s kartsinoidnym sindromom.