title: [The prognostic significance of basic risk factors of ischemic heart disease and its changes in carrying out preventive measures].
abstract: The paper treats the results of an analysis of the assessment of the main risk factors within the framework of the program for multifactorial prophylaxis of coronary heart disease in the populations with varying involvement into preventive measures. Using standard methods altogether 6566 men aged 40-59 years were examined in the area of two district polyclinics with a purpose of diagnosing coronary heart disease and risk factors of its development. During 5 years, measures aimed at active primary and secondary prophylaxis of coronary heart disease were carried out in one of the groups. Prospective survey over the death rate has demonstrated that cardiovascular diseases rank the first in the structure of the death rate among the adult male population, with their portion being increased with age. Studies into the relationship between the death rate and the main risk factors in the population provided evidence that risk of the death from cardiovascular diseases rises with an increase in the systolic and diastolic arterial pressure, in the body weight index, and in total cholesterol. The active composite preventive measures brought about a significant reduction in risk of the death from cardiovascular diseases, in the incidence of the fresh cases of myocardial infarction, and brain stroke. At the same time the death rate of cardiovascular diseases dropped by 40.7% as compared to the expected one, the number of lethal cases due to various reasons by 12.7%, an the incidence of myocardial infarction and brain stroke by 18.8%.
authors.forename: L V
authors.initials: LV
authors.lastname: Chazova
authors.forename: A M
authors.initials: AM
authors.lastname: Kalinina
authors.forename: L I
authors.initials: LI
authors.lastname: Pavlova
authors.forename: A D
authors.initials: AD
authors.lastname: Deev
mesh_terms: D000328:Adult; D000367:Age Factors; D001794:Blood Pressure; D001835:Body Weight; D015984:Causality; D003327:Coronary Disease / Q000453:epidemiology / Q000401:mortality / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology / Q000401:mortality / Q000517:prevention & control; D011379:Prognosis; D011446:Prospective Studies; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D014586:USSR / Q000453:epidemiology
vernacular_title: Prognosticheskaia znachimost' osnovnykh faktorov riska ishemicheskoĭ bolezni serdtsa i ee izmeneniia pri provedenii profilakticheskikh meropriiatiĭ.