title: Primary mediastinal endodermal sinus tumors: CT evaluation.
abstract: Five patients with primary mediastinal endodermal sinus tumor have been evaluated by computed tomography (CT). The tumors were all located in the anterior mediastinum. Prechemotherapy CT demonstrated large, irregularly enhancing inhomogeneous masses without fat components. Calcification was visualized in two tumors. Some parts of the pleura-lung interface were irregular in four cases. Obliteration of fat planes to pericardium and chest wall was evident in all cases, and there was infiltration of intercostal muscles in four. Postchemotherapy CT in two patients who responded to chemotherapy showed either newly developed cystic lesions or cystic change of the original mediastinal mass. The cystic masses had more regular borders, a homogeneous hypodense center, and a smooth peripheral rim of contrast-enhancing tissue.
authors.affiliation: Department of Radiotherapy, Queen Mary Hospital, Hong Kong.
authors.forename: J S
authors.initials: JS
authors.lastname: Sham
authors.forename: F L
authors.initials: FL
authors.lastname: Chan
authors.forename: W H
authors.initials: WH
authors.lastname: Lau
authors.forename: P H
authors.initials: PH
authors.lastname: Choi
authors.forename: D
authors.initials: D
authors.lastname: Choy
mesh_terms: D000293:Adolescent; D000328:Adult; D002114:Calcinosis / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy; D008649:Mesonephroma / Q000000981:diagnostic imaging* / Q000188:drug therapy; D013997:Time Factors; D014057:Tomography, X-Ray Computed