Transfusion of ABO-incompatible platelets causing severe haemolytic reaction.
Not infrequently clinical demand dictates that patients receive transfusions of ABO-incompatible platelets when there is a short supply of group-specific platelets. This carries a risk of causing a haemolytic reaction, as illustrated in the clinical case we report. In discussing this potential complication, we suggest a strategy for avoiding it.
Reis
M D
MD
Department of Laboratory Haematology, Sunnybrook Medical Centre, Toronto, Ontario, Canada.
Coovadia
A S
AS
D000017:ABO Blood-Group System / Q000276:immunology*; D000741:Anemia, Aplastic / Q000628:therapy; D001787:Blood Group Incompatibility; D001792:Blood Platelets / Q000276:immunology; D006461:Hemolysis / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D017713:Platelet Transfusion; D065227:Transfusion Reaction
D000017:ABO Blood-Group System