title: [Usefulness of long-term follow-up of gastric ulcer: a case load contribution to the natural history of gastric ulcer in relation to treatment with H2-blockaders].
abstract: Thorough long-term clinical, endoscopic and biopsy follow-up (from 6 months to greater than 8 years; mean follow-up: 3 years 3 months) of a group of 202 cases of apparently benign gastric ulcer has enabled us to evaluate the natural history of gastric ulcer in relation to medical therapy with H2-blockers and to patient compliance when using such drugs. The results confirm the efficacy of H2-antagonist therapy in gastric ulcer healing and in the prevention of relapse. Thorough follow-up, moreover, made it possible to keep surgical operations for non-neoplastic causes down to very low numbers, only 3 patients (1.5%) being operated on for haemorrhagic emergencies and 12 (6%) for non-response to therapy.
authors.affiliation: U.L.S.S. N. 17-Regione Veneto, Presidio Ospedaliero di Noale, Servizio di Endoscopia.
authors.forename: M
authors.initials: M
authors.lastname: De Bernardin
authors.forename: E
authors.initials: E
authors.lastname: Bortolozzi
authors.forename: F
authors.initials: F
authors.lastname: Danieli
authors.forename: U
authors.initials: U
authors.lastname: Sicari
authors.forename: G
authors.initials: G
authors.lastname: Pinto
authors.forename: F
authors.initials: F
authors.lastname: Gatto
authors.forename: N
authors.initials: N
authors.lastname: Bragato
authors.forename: G F
authors.initials: GF
authors.lastname: Corso
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D001706:Biopsy; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D005773:Gastroscopy; D006635:Histamine H2 Antagonists / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013276:Stomach Ulcer / Q000188:drug therapy* / Q000473:pathology; D013997:Time Factors
chemical_list: D000897:Anti-Ulcer Agents; D006635:Histamine H2 Antagonists
vernacular_title: Utilità di un follow-up endoscopico a lungo termine nell'ulcera gastrica: contributo casistico alla storia naturale dell'ug in rapporto alla terapia con h2-bloccanti.