Ocular Lyme borreliosis.
In six patients with ocular Lyme borreliosis, bilateral granulomatous iridocyclitis and vitritis were present in five. One of these five also had bilateral optic neuritis. Another patient developed combined trochlear and facial nerve palsies. A syndrome resembling pars planitis with atypical features such as granulomatous keratic precipitates and posterior synechiae should prompt a search for Lyme borreliosis. Topical corticosteroid therapy is necessary to prevent complications of anterior segment inflammation caused by Lyme uveitis, but the benefit of systemic and periocular corticosteroids is uncertain. Oral antibiotics may be effective in treating early stages of ocular Lyme borreliosis. In later stages, intravenous antibiotic therapy is indicated.
Winward
K E
KE
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, Florida 33101.
Smith
J L
JL
Culbertson
W W
WW
Paris-Hamelin
A
A
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay; D015822:Eye Infections, Parasitic / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D015863:Iridocyclitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D008193:Lyme Disease / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D009902:Optic Neuritis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D014792:Visual Acuity; D014822:Vitreous Body / Q000503:physiopathology
D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents