Langerhans cells in delayed skin reactions to inhalant allergens in atopic dermatitis--an electron microscopic study.
Langerhans cells at the site of patch tests to inhaled allergens in patients with atopic dermatitis were investigated. Within 24 h the Langerhans cells showed increased cellular activity and became apposed to mononuclear cells. This supports the view that Langerhans cells are involved in antigen presentation in atopic dermatitis.
Najem
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Hull
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D000328:Adult; D000368:Aged; D000485:Allergens / Q000008:administration & dosage / Q000276:immunology*; D003876:Dermatitis, Atopic / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007801:Langerhans Cells / Q000276:immunology / Q000648:ultrastructure*; D008854:Microscopy, Electron; D008875:Middle Aged; D010328:Patch Tests
D000485:Allergens