First evidences of the formation of a vanadyl(IV) complex of bleomycin.
Results of visible/ultraviolet and infrared spectroscopic measurements, as well as chemical evidence are presented which support the formation of a 2:1 bleomycin-VO2+ complex. The information obtained also allows some considerations concerning the probable coordination sphere of the vanadyl ion.
Baran
E J
EJ
D001761:Bleomycin / Q000032:analysis*; D055598:Chemical Phenomena; D002621:Chemistry; D004578:Electron Spin Resonance Spectroscopy; D006863:Hydrogen-Ion Concentration; D013056:Spectrophotometry, Ultraviolet; D013329:Structure-Activity Relationship; D014639:Vanadium / Q000032:analysis*
D014639:Vanadium; D001761:Bleomycin