Platelet monoamine oxidase-B activity in Parkinson's disease.
Platelet MAO-B levels have been investigated in seventeen consecutively diagnosed and previously untreated patients with idiopathic Parkinson's disease using the non-hydroxylated catecholamine, beta-phenylethylamine, as substrate. Patients with Parkinson's disease had MAO-B activity levels that were considerably higher than sex and age matched normal controls or patients with Motor neurone disease or Myasthenia gravis.
Steventon
G B
GB
Department of Neurology, Queen Elizabeth Medical Centre, Birmingham, United Kingdom.
Sturman
S G
SG
Heafield
M T
MT
Waring
R H
RH
Napier
J
J
Williams
A C
AC
D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000201:enzymology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008995:Monoamine Oxidase / Q000378:metabolism*; D010302:Parkinson Disease, Secondary / Q000097:blood* / Q000201:enzymology
D008995:Monoamine Oxidase