title: A monoclonal antibody to the galactan from Helix pomatia snails recognizes beta-(1,6)-linked D-galactose residues.
abstract: Using the hybridoma technique, a series of four monoclonal antibodies to the galactan isolated from albumin glands of wine yard snails (Helix pomatia) could be generated. Characterization of the binding properties of one of these antibodies revealed a specificity for beta-(1,6)-glycosidically linked D-galactose residues. This could be demonstrated by reaction of the antibody with beta-(1,6)-D-galactans and by the D-galactose-inhibitable binding to group B streptococci of type II, which possess beta-(1,6)-linked D-galactose as immuno-determinant group.
authors.forename: J
authors.initials: J
authors.lastname: Sölter
authors.forename: G
authors.initials: G
authors.lastname: Uhlenbruck
authors.forename: H
authors.initials: H
authors.lastname: Düvel
authors.forename: B
authors.initials: B
authors.lastname: Raftery
authors.forename: R
authors.initials: R
authors.lastname: Mohr
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000918:Antibody Specificity; D002240:Carbohydrate Sequence; D000939:Epitopes; D005685:Galactans / Q000276:immunology*; D006372:Helix, Snails / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal; D000939:Epitopes; D005685:Galactans