title: [Idiopathic and diuretic-induced edema].
abstract: In female patients with intermitting or permanent inclination to oedemas and intake of diuretics after exclusion of cardiac, renal, venous and lymphogenic causes should be thought of the clinical picture of the idiopathic and diuretic-induced oedema, respectively. Pathophysiologically, the two forms underlie an activation of the renin-angiotensin-aldosterone system with subsequent retention of water and common salt. In these cases the intake of diuretics is not indicated and may lead to the chronification of the oedemas. Therefore the physician is confronted with the responsible task to finish the permanent intake of diuretics by adequate explanation of the pathophysiological and pharmacological connections and to care for the frequently neurotic female patients in this difficult time. For a short time a treatment with aldosterone antagonists can be recommended and first therapeutic experiments with the application of ACE-inhibitors were successful. A special diet poor in common salt is not necessary and in the individual case a psychotherapeutic treatment of the female patients should be carried out.
authors.affiliation: Medizinischen Ambulanten Versorgungsbereich VI, Karl-Marx-Stadt.
authors.forename: K
authors.initials: K
authors.lastname: Schirmer
authors.forename: M
authors.initials: M
authors.lastname: Gläser
mesh_terms: D000328:Adult; D004305:Dose-Response Relationship, Drug; D004487:Edema / Q000139:chemically induced*; D005260:Female; D005665:Furosemide / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007674:Kidney Diseases / Q000150:complications; D007677:Kidney Function Tests; D012084:Renin-Angiotensin System / Q000187:drug effects; D012307:Risk Factors; D014882:Water-Electrolyte Balance / Q000187:drug effects
chemical_list: D005665:Furosemide
vernacular_title: Zur Problematik idiopathischer und diuretikainduzierter Odeme.