Effect of tea on 12-O tetradecanoyl-phorbol-13 acetate (TPA) induced promotion of transformation in JB6 mouse epidermal cells.
The extract of black and green tea (Camellia sp.) which are widely consumed as commonest beverage, decreased the 12-O-Tetradecanoylphorbol-13 acetate (TPA) induced promotion of transformation in dose dependent manner in JB6 mouse epidermal cell system. The probable mechanisms have been discussed.
Jain
A K
AK
Shimoi
K
K
Nakamura
Y
Y
Sano
M
M
Tomita
I
I
D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage; D002461:Cell Line, Transformed / Q000187:drug effects; D002471:Cell Transformation, Neoplastic / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D051379:Mice; D013662:Tea; D013755:Tetradecanoylphorbol Acetate
D000975:Antioxidants; D013662:Tea; D013755:Tetradecanoylphorbol Acetate