[An assay for aldosterone precursors: a tool for clinical diagnosis and adrenal physiopathology].
After their contribution to the study of 18 hydroxycorticosterone as an intermediate in aldosterone biosynthesis the authors present here a new series of assays for the measurement of plasma aldosterone precursors as a pertinent tool in the extensive study and clinical evaluation of the mineralocorticoid function of the adrenal. These radioimmunoassays must be undertaken under strict technical conditions: time of blood withdrawal and also posture. Their use is irrelevant in any other clinical feature but the salt loss syndrome and hyper mineralo-corticism together with or without high plasma aldosterone.
Legrand
J C
JC
Aupetit
B
B
D015069:18-Hydroxycorticosterone / Q000097:blood* / Q000378:metabolism; D000308:Adrenocortical Hyperfunction / Q000097:blood / Q000175:diagnosis*; D000450:Aldosterone / Q000096:biosynthesis*; D003345:Corticosterone / Q000031:analogs & derivatives*; D006801:Humans; D011863:Radioimmunoassay / Q000379:methods
D000450:Aldosterone; D015069:18-Hydroxycorticosterone; D003345:Corticosterone
Dosage des précurseurs de l'aldostérone: intérêt diagnostique et physiopathologique.