title: Prognostic indicators in tibial shaft fractures: serum creatinine kinase activity.
abstract: Serum creatinine phosphokinase (CPK) levels were measured serially in 50 adults with closed tibial shaft fractures. CPK activity increased significantly after fracture (p less than 0.001). High energy and slowly healing fractures had significantly higher levels than low energy and normally healing fractures, respectively. Thus, CPK determinations could be used to assess the severity of trauma and possibly prognosis in tibial shaft fractures.
authors.affiliation: Department of Orthopaedic Surgery, Leicester Royal Infirmary, England.
authors.forename: O O
authors.initials: OO
authors.lastname: Oni
authors.forename: A
authors.initials: A
authors.lastname: Fenton
authors.forename: S J
authors.initials: SJ
authors.lastname: Iqbal
authors.forename: P J
authors.initials: PJ
authors.lastname: Gregg
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood*; D003402:Creatine Kinase / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011859:Radiography; D013978:Tibial Fractures / Q000097:blood* / Q000000981:diagnostic imaging / Q000503:physiopathology; D014945:Wound Healing
chemical_list: D015415:Biomarkers; D003402:Creatine Kinase