title: Renal vein thrombosis and response to therapy in a newborn due to protein C deficiency.
abstract: A newborn infant was diagnosed as having renal vein thrombosis due to heterozygous protein C deficiency and no other predisposing factor for thrombosis. He responded adequately to treatment with streptokinase, fresh frozen plasma and subsequent anticoagulation with heparin and warfarin (Coumadin). Four years from diagnosis he remains well with no recurrence of thrombosis and with normal renal function.
authors.affiliation: Department of Paediatrics, BC Children's Hospital, Vancouver, Canada.
authors.forename: P C
authors.initials: PC
authors.lastname: Rogers
authors.forename: M P
authors.initials: MP
authors.lastname: Silva
authors.forename: J E
authors.initials: JE
authors.lastname: Carter
authors.forename: L D
authors.initials: LD
authors.lastname: Wadsworth
mesh_terms: D004359:Drug Therapy, Combination; D006493:Heparin / Q000627:therapeutic use; D006579:Heterozygote; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011486:Protein C / Q000235:genetics; D020151:Protein C Deficiency; D012082:Renal Veins; D013300:Streptokinase / Q000627:therapeutic use; D013927:Thrombosis / Q000188:drug therapy / Q000209:etiology*; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D011486:Protein C; D014859:Warfarin; D006493:Heparin; D013300:Streptokinase