title: Rebound surges of intracranial pressure as a consequence of forced ultrafiltration used to control intracranial pressure in patients with severe hepatorenal failure.
abstract: Cerebral edema remains the most common immediate cause of death in patients with fulminant hepatic failure. We have used ultrafiltration as a method of controlling intracranial pressure (ICP) when other measures have failed. Two cases in which an initial decrease in ICP was followed by a marked rebound increase resulting in death are reported.
authors.affiliation: Department of Renal Medicine, James' University Hospital, Leeds, England.
authors.forename: A
authors.initials: A
authors.lastname: Davenport
authors.forename: E J
authors.initials: EJ
authors.lastname: Will
authors.forename: M S
authors.initials: MS
authors.lastname: Losowsky
mesh_terms: D000082:Acetaminophen / Q000506:poisoning; D058186:Acute Kidney Injury / Q000139:chemically induced / Q000628:therapy*; D000328:Adult; D001929:Brain Edema / Q000517:prevention & control; D062787:Drug Overdose; D005260:Female; D006440:Hemofiltration / Q000009:adverse effects*; D006501:Hepatic Encephalopathy / Q000139:chemically induced / Q000628:therapy*; D006801:Humans; D007427:Intracranial Pressure; D008297:Male; D011559:Pseudotumor Cerebri / Q000209:etiology*
chemical_list: D000082:Acetaminophen