title: The effectiveness of protein supplementation on the nutritional management of patients on CAPD.
abstract: Repeated episodes of peritonitis cause malnutrition in CAPD patients because of increased protein loss into the dialysate, a high protein catabolic rate (PCR), and/or a decrease in appetite. The purpose of this study was to investigate whether protein supplements could improve the nutritional status of CAPD patients and secondarily reduce their incidence of peritonitis. Eight patients on CAPD were studied for 2 months as a baseline, then given protein supplementation for 4 months. There was significant (p less than .05) increase in dietary intake and nitrogen balance, with supplementation. The PCR decreased significantly (p less than .05). There was a concomitant decrease in the incidence of new episodes of peritonitis. In conclusion, protein supplementation can improve the catabolic state of CAPD patients.
authors.affiliation: School of Dietetics and Human Nutrition, Department of Surgery, Montreal General Hospital/McGill University, Quebec, Canada.
authors.forename: R A
authors.initials: RA
authors.lastname: Elias
authors.forename: A H
authors.initials: AH
authors.lastname: McArdle
authors.forename: R F
authors.initials: RF
authors.lastname: Gagnon
mesh_terms: D000368:Aged; D004044:Dietary Proteins / Q000008:administration & dosage* / Q000378:metabolism; D002149:Energy Intake; D005260:Female; D005527:Food, Fortified; D006801:Humans; D007676:Kidney Failure, Chronic / Q000378:metabolism / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009584:Nitrogen / Q000378:metabolism; D009752:Nutritional Status; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects; D010538:Peritonitis / Q000209:etiology / Q000517:prevention & control; D011506:Proteins / Q000378:metabolism
chemical_list: D004044:Dietary Proteins; D011506:Proteins; D009584:Nitrogen