title: [Hospital epidemic of Clostridium difficile diarrhea: demonstration of cross-infection using a typing technic].
abstract: Two hospital outbreaks of Clostridium difficile diarrhoea in two general surgery units of different hospitals are described. Moreover, the results of a study on the circulation of C. difficile in a neurosurgery unit following two cases of colitis are reported. C. difficile strains isolated from patients and environment have been typed using antimicrobial susceptibility testing and electrophoretic profiles of EDTA-extracted proteins. The majority of strains isolated in each hospital shared the same protein profile and the same pattern of antibiotic susceptibility. This provides strong evidence of cross-infection and hospital acquisition of C. difficile.
authors.forename: M
authors.initials: M
authors.lastname: Cerquetti
authors.forename: A
authors.initials: A
authors.lastname: Pantosti
authors.forename: G
authors.initials: G
authors.lastname: Gentile
authors.forename: F
authors.initials: F
authors.lastname: D'Ambrosio
authors.forename: P
authors.initials: P
authors.lastname: Mastrantonio
mesh_terms: D001426:Bacterial Proteins / Q000032:analysis; D001427:Bacterial Toxins / Q000032:analysis; D003013:Clostridium / Q000145:classification / Q000302:isolation & purification; D003015:Clostridium Infections / Q000453:epidemiology*; D003092:Colitis / Q000453:epidemiology / Q000209:etiology* / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology*; D004196:Disease Outbreaks; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008826:Microbial Sensitivity Tests
chemical_list: D001426:Bacterial Proteins; D001427:Bacterial Toxins
vernacular_title: Epidemie ospedaliere di diarrea da Clostridium difficile: dimostrazione di infezione crociata mediante tecniche di tipizzazione.