title: [Atherogenic dyslipidemia in adolescents: its relation to ischemic heart disease in their fathers and the possibility of its prognosis].
abstract: Comparison of a group of adolescents aged 11-16 years whose fathers had angiographically documented coronary atherosclerosis in youth with those matched by sex and age whose parents were clinically healthy yielded the following discriminant function (DF) involving lipid and apoprotein indices of the plasma lipid system: DF = [apo B] X 0.03-[HDL cholesterol] X 0.04-0.81. DF greater than or equal to 0 discriminates from the controls 32% of the offsprings from the fathers with a history, DF less than 0 correctly classifies 98% of adolescents from the controls. The adolescents who have DF greater than or equal to 0 amounted to about 19% in representative samples of Moscow adolescents. Moreover, DF with 80% probability makes it possible to predict the time course of serum lipid levels in adolescents within 2 years.
authors.forename: V A
authors.initials: VA
authors.lastname: Mete'lskaia
authors.forename: E D
authors.initials: ED
authors.lastname: Aĭngorn
authors.forename: G Ia
authors.initials: GIa
authors.lastname: Maslennikova
authors.forename: T G
authors.initials: TG
authors.lastname: Dorofeeva
authors.forename: N N
authors.initials: NN
authors.lastname: Gorchakova
authors.forename: A E
authors.initials: AE
authors.lastname: Sipiagina
authors.forename: T V
authors.initials: TV
authors.lastname: Ruzhanskaia
authors.forename: I V
authors.initials: IV
authors.lastname: Grigo'reva
authors.forename: A M
authors.initials: AM
authors.lastname: Olfe'rev
authors.forename: N A
authors.initials: NA
authors.lastname: Beloko'n
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003324:Coronary Artery Disease / Q000097:blood / Q000209:etiology / Q000235:genetics*; D005220:Fathers; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000150:complications*; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors
chemical_list: D008055:Lipids
vernacular_title: Aterogennye dislipidemii u podrostkov: svia'z s nalichiem ishemi- cheskoĭ bolezni serdtsa u ottsov, vozmozhnos't prognozirovaniia.