[Thrombogenicity of the arterioles and venules in experimental tumor growth].
The authors studied laser radiation induced thrombogenesis in microvessels--arterioles and venules--of the mesentery of tumor-carrier rats. Statistically significant increase of thrombogenic potential was revealed in the venules on the 7th day after reinoculation of Pliss' lymphosarcoma, and only a tendency to its increase in the arteries. At the same time an increase was noted of the aggregation activity of blood platelets and inhibition of their deaggregation. The results of the study open new aspects of the phenomenon of generalized changes in the system of regional blood circulation characteristic of tumor growth and indicate a new means of its study.
Petrishchev
N N
NN
Georgadze
G M
GM
Natadze
T G
TG
D000818:Animals; D001160:Arterioles / Q000503:physiopathology / Q000528:radiation effects; D007834:Lasers; D008228:Lymphoma, Non-Hodgkin / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D008297:Male; D008643:Mesentery / Q000098:blood supply* / Q000528:radiation effects; D009368:Neoplasm Transplantation; D010257:Paraneoplastic Syndromes / Q000097:blood / Q000209:etiology / Q000503:physiopathology; D010974:Platelet Aggregation / Q000502:physiology / Q000528:radiation effects; D051381:Rats; D013927:Thrombosis / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D014699:Venules / Q000503:physiopathology / Q000528:radiation effects
Trombogennost' arteriol i venul pri éksperimental'nom opukholevom roste.