Carrier presentation: a possible strategy for selective in vivo amplification of specific T cells.
A strategy for selective in vivo amplification of specific T cells by carrier presentation is outlined here. This hypothesis addresses the possible physiological significance of expression of MHC II molecules by T cells, and attempts to highlight the possibility of harnessing the phenomenon for therapeutic use in medicine.
Saxena
H M
HM
Cancer Research Campaign Laboratories, University Park, Nottingham, U.K.
Robins
R A
RA
Baldwin
R W
RW
D002352:Carrier Proteins / Q000502:physiology; D006801:Humans; D007167:Immunotherapy; D007375:Interleukin-1 / Q000502:physiology; D007376:Interleukin-2 / Q000096:biosynthesis; D008213:Lymphocyte Activation; D009369:Neoplasms / Q000628:therapy*; D013601:T-Lymphocytes / Q000502:physiology*
D002352:Carrier Proteins; D007375:Interleukin-1; D007376:Interleukin-2