Serum potassium concentrations following succinylcholine in patients undergoing beta-adrenoceptor blocking therapy.
Efflux of serum potassium following succinylcholine was compared in surgical patients undergoing low-dose, long-term beta 1-adrenoceptor or beta 1,2-adrenoceptor blocking therapy and in those receiving neither of these therapies. There were no significant differences in serum potassium concentration prior to, and over a study period of, 2 hours following succinylcholine administration among the three groups of patients.
From
R P
RP
Department of Anesthesia, University of Iowa College of Medicine, Iowa City 52242.
Mehta
M P
MP
Pathak
D
D
D000284:Administration, Oral; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D001262:Atenolol / Q000008:administration & dosage / Q000627:therapeutic use; D001794:Blood Pressure / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008790:Metoprolol / Q000008:administration & dosage / Q000627:therapeutic use; D008875:Middle Aged; D009248:Nadolol / Q000008:administration & dosage / Q000627:therapeutic use; D009883:Ophthalmic Solutions; D011188:Potassium / Q000097:blood*; D011433:Propranolol / Q000008:administration & dosage / Q000627:therapeutic use; D013390:Succinylcholine / Q000494:pharmacology*; D013997:Time Factors; D013999:Timolol / Q000008:administration & dosage / Q000627:therapeutic use
D000319:Adrenergic beta-Antagonists; D009883:Ophthalmic Solutions; D009248:Nadolol; D001262:Atenolol; D013999:Timolol; D011433:Propranolol; D008790:Metoprolol; D013390:Succinylcholine; D011188:Potassium