Aspects of pharmaceutical and chemical standardization of patch test materials.
The choice of vehicle for patch test materials is important for the bioavailability and stability of the allergens. Examples are given from the standardization of the TRUE Test and include caine mix, Kathon CG, and fragrance mix.
Kreilgård
B
B
Department of Analytical Chemistry, Pharmacia AS, Hillerød, Denmark.
Hansen
J
J
D000171:Acrolein / Q000031:analogs & derivatives; D000080462:Acyclic Monoterpenes; D000485:Allergens / Q000493:pharmacokinetics / Q000592:standards*; D001566:Benzocaine; D002482:Cellulose / Q000031:analogs & derivatives / Q000493:pharmacokinetics; D003877:Dermatitis, Contact / Q000175:diagnosis; D003992:Dibucaine; D005054:Eugenol / Q000031:analogs & derivatives; D006801:Humans; D010328:Patch Tests / Q000592:standards*; D014677:Pharmaceutical Vehicles / Q000493:pharmacokinetics; D011205:Povidone / Q000493:pharmacokinetics; D020005:Propanols; D011786:Quality Control; D012882:Skin Tests / Q000592:standards*; D013729:Terpenes; D013748:Tetracaine; D013844:Thiazoles
D000080462:Acyclic Monoterpenes; D000485:Allergens; D014677:Pharmaceutical Vehicles; D020005:Propanols; D013729:Terpenes; D013844:Thiazoles; D013748:Tetracaine; D005054:Eugenol; C037057:Kathon 886; C036643:isoeugenol; D000171:Acrolein; C020755:hydroxycitronellal; D002482:Cellulose; C008079:hydroxypropylcellulose; D011205:Povidone; D003992:Dibucaine; C007836:geraniol; C012843:cinnamaldehyde; C020722:cinnamyl alcohol; D001566:Benzocaine