[Reevaluation of microdensitometry method in diagnosing osteoporosis].
In order to confirm whether Inoue's microdensitometry (MD) method can assess the severity of spinal or femoral osteoporosis, the evaluation of osteoporosis in 116 patients was carried out by four methods: The MD method using X-ray picture of the hand along with an aluminium step-wedge, Itami index using X-ray picture of lumbar vertebrae, Singh index using X-ray picture of femur, and QDR method assessing BMC. The total MD score correlated significantly with the Itami index (rs = 0.691, p less than 0.001), but did not correlate significantly with the Singh index. In the group of no osteoporosis judged by the Itami index, the total MD score showed a 6.4% false positive rate. In the group of osteoporosis judged by the Itami index, the total MD score showed a 15.8% false negative rate. In order to establish a more reliable index, we developed a new H.I index (MCI X GSmin X 100). With this H.I index, the false positive rate was 1.3%, and false negative rate was 0%, and then it correlated significantly with the BMD of the lumbar vertebrae (r = 0.759, p less than 0.001). It is concluded that the MD method reflects totally osteoporotic bone loss of vertebrae but the total MD score is not so reliable, and the H.I index is a more exact indicator of osteoporosis than the total MD score.
Honjo
S
S
Department of Obstetrics and Gynecology, Gunma University School of Medicine, Maebashi.
Igarashi
M
M
Mizunuma
H
H
D015502:Absorptiometry, Photon / Q000379:methods; D000328:Adult; D000368:Aged; D015519:Bone Density; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008875:Middle Aged; D010024:Osteoporosis / Q000175:diagnosis*; D011237:Predictive Value of Tests