[The effect of regulator peptides on pancreatic endocrine function in experimental acute pancreatitis].
The comparative analysis of the influence on the glucose metabolism of rats in acute pancreatitis of synthetic analogues was made: somatostatin, calcitonin, leu-enkefalin-dalargin. It was shown that dalargin has the maximum normalizing effect as a result of its antistress qualities. Physiological reaction of beta-cells is preserved in infusion of somatostatin. However, infusion of calcitonin results in the distortion of counterregulatory action of insulin and glucagon.
Tsvirkun
V V
VV
Grigorevskiĭ
V P
VP
Botsmanov
K V
KV
Bocharova
V S
VS
D000208:Acute Disease; D000818:Animals; D002116:Calcitonin / Q000494:pharmacology; D004743:Enkephalin, Leucine / Q000031:analogs & derivatives / Q000494:pharmacology; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives*; D008297:Male; D010179:Pancreas / Q000187:drug effects* / Q000378:metabolism; D010195:Pancreatitis / Q000097:blood / Q000503:physiopathology*; D010455:Peptides / Q000494:pharmacology*; D051381:Rats; D013004:Somatostatin / Q000494:pharmacology; D013997:Time Factors
D010455:Peptides; D013004:Somatostatin; D004743:Enkephalin, Leucine; D016308:Enkephalin, Leucine-2-Alanine; D002116:Calcitonin; C040996:enkephalin-Leu, Ala(2)-Arg(6)-
Vliianie reguliatornykh peptidov na éndokrinnuiu funktsiiu podzheludochnoĭ zhelezy pri éksperimental'nom ostrom pankreatite.