title: Thermal salivation in rats, anesthetized with barbiturates, chloralose, urethane and ketamine.
abstract: 1. The relationship between thermal salivation (TS) and thermoregulation was studied in anesthetized rats. 2. Of the 6 anesthetics used, ketamine-anesthetized rats secreted the largest amount of saliva. Salivation, however, was thermal and not induced by ketamine itself. 3. Ketamine-anesthetized rats readily secreted saliva at core temperatures less than 40 degrees C but TS was remarkably enhanced by hyperthermia of 40-42.5 degrees C. 4. The equilibrium phase in the triphasic heat response of core temperature was a consequence of equilibrium between heat gain and heat loss by salivation.
authors.affiliation: Department of Physiology, Nagoya City University Medical School, Japan.
authors.forename: F
authors.initials: F
authors.lastname: Furuyama
authors.forename: Y
authors.initials: Y
authors.lastname: Ishida
authors.forename: M
authors.initials: M
authors.lastname: Furuyama
authors.forename: T
authors.initials: T
authors.lastname: Hashitani
authors.forename: Y
authors.initials: Y
authors.lastname: Isobe
authors.forename: H
authors.initials: H
authors.lastname: Sato
authors.forename: K
authors.initials: K
authors.lastname: Ohara
authors.forename: H
authors.initials: H
authors.lastname: Nishino
mesh_terms: D000777:Anesthetics / Q000494:pharmacology*; D000818:Animals; D001463:Barbiturates / Q000494:pharmacology; D001833:Body Temperature Regulation / Q000187:drug effects*; D002698:Chloralose / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D006358:Hot Temperature; D007649:Ketamine / Q000494:pharmacology; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012472:Salivation / Q000187:drug effects*; D014520:Urethane / Q000494:pharmacology
chemical_list: D000777:Anesthetics; D001463:Barbiturates; D002698:Chloralose; D014520:Urethane; D007649:Ketamine