Detection of sperm-bound antibodies in the male partners of infertile couples using the immunobead test.
The aim of this investigation was to determine the incidence of sperm-bound antibodies in the male partners of an unselected infertile population using an immunologically specific test (IBT). With this method 34 out of 450 infertile men (7.55%) were positive for one or more of the immunoglobulins IgA, IgG and IgM. For IgG and IgA, the majority of antibody binding was located on the entire sperm with a minor amount bound to the head or tail. For the IgM, the majority of the binding was detected to the tail tip, and tail binding was observed only in a minority of cases.
Gregoriou
O
O
Second Department of Obstetrics and Gynecology, University of Athens, Areteion Hospital, Greece.
Vitoratos
N
N
Legakis
N
N
Gregoriou
G
G
Zourlas
P A
PA
D006801:Humans; D007132:Immunoglobulin Isotypes / Q000032:analysis*; D007159:Immunologic Tests; D007248:Infertility, Male / Q000175:diagnosis* / Q000276:immunology; D008297:Male; D013084:Sperm-Ovum Interactions / Q000276:immunology; D013094:Spermatozoa / Q000032:analysis* / Q000276:immunology
D007132:Immunoglobulin Isotypes