title: [Synthesis of new aminoalkanol derivatives of benzofuran with potential beta-adrenolytic activity].
abstract: Two routes of synthesis of 2-acetyl-7-hydroxy-6-methoxy-3-methylbenzofuran and some of its aminoalkanol ethers are described. Six compounds proved to exert the expected antiarrhythmic and hypotensive effects.
authors.forename: T
authors.initials: T
authors.lastname: Zawadowski
authors.forename: S
authors.initials: S
authors.lastname: Suski
authors.forename: S
authors.initials: S
authors.lastname: Rump
authors.forename: G
authors.initials: G
authors.lastname: Borkowska
mesh_terms: D000318:Adrenergic beta-Agonists; D000818:Animals; D000889:Anti-Arrhythmia Agents; D000959:Antihypertensive Agents; D001145:Arrhythmias, Cardiac / Q000188:drug therapy* / Q000503:physiopathology; D001572:Benzofurans / Q000138:chemical synthesis / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects* / Q000502:physiology; D004353:Drug Evaluation, Preclinical; D006329:Heart Conduction System / Q000187:drug effects* / Q000503:physiopathology; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D051379:Mice; D011412:Propanolamines / Q000138:chemical synthesis / Q000627:therapeutic use*; D051381:Rats
chemical_list: D000318:Adrenergic beta-Agonists; D000889:Anti-Arrhythmia Agents; D000959:Antihypertensive Agents; D001572:Benzofurans; D011412:Propanolamines
vernacular_title: Synteza nowych, aminoalkanolowych pochodnych benzofuranu o spodziewanym działaniu beta-adrenolitycznym.