title: Fetal death from chlamydial infection across intact amniotic membranes.
abstract: We report a case of a fetal death at 34 weeks' gestation with intact membranes. An autopsy confirmed intrauterine pneumonia as a result of Chlamydia trachomatis. Staining of the lung tissue with a direct fluorescein-conjugated Chlamydia-specific monoclonal antibody assay revealed a pattern typical of a Chlamydia trachomatis infection. This case supports the thesis that Chlamydia crosses fetal membranes and produces disease.
authors.affiliation: Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill 27599-7570.
authors.forename: J M
authors.initials: JM
authors.lastname: Thorp
authors.forename: V L
authors.initials: VL
authors.lastname: Katz
authors.forename: L J
authors.initials: LJ
authors.lastname: Fowler
authors.forename: J T
authors.initials: JT
authors.lastname: Kurtzman
authors.forename: W A
authors.initials: WA
authors.lastname: Bowes
mesh_terms: D000293:Adolescent; D000650:Amnion / Q000382:microbiology*; D002690:Chlamydia Infections / Q000150:complications* / Q000635:transmission; D005260:Female; D005313:Fetal Death / Q000209:etiology*; D006801:Humans; D008431:Maternal-Fetal Exchange; D011247:Pregnancy