[Reaction of Langerhans cells of the corneal epithelium to topically applied lead].
Twenty guinea pigs were given a solution of lead acetate into the conjunctival sac. Ten animals from the control group received distilled water. In the contaminated group one observed conjunctival irritation and a paralimbal opacification of the cornea. Histopathological examination of the contaminated animals showed a distinctly lower number of the Langerhans' cells in comparison with the control group.
Niebrój
T
T
Gruszczyńska
M
M
D000287:Administration, Topical; D000818:Animals; D002452:Cell Count / Q000187:drug effects; D003315:Cornea / Q000187:drug effects* / Q000473:pathology; D003318:Corneal Opacity / Q000139:chemically induced* / Q000473:pathology; D004848:Epithelium / Q000187:drug effects / Q000473:pathology; D006168:Guinea Pigs; D007801:Langerhans Cells / Q000187:drug effects* / Q000473:pathology; D009942:Organometallic Compounds / Q000008:administration & dosage / Q000009:adverse effects*
D009942:Organometallic Compounds; C008261:lead acetate
Reakcja komórek Langerhansa nabłonka rogówki na miejscowo podany ołów.