title: Cervical prostaglandin injection: a novel method of administration for ripening the cervix and induction of labor.
abstract: Twenty pregnant women with greater than or equal to 36 weeks gestation and Bishop score of less than or equal to 4 were subjected to either intracervical injection of PGE2 (0.25 mg) every 4 h to ripen the cervix and induce labor (study group n = 10) or injection of only the diluent (control group n = 10). PGE2 cases showed significant increase in Bishop score and were successfully induced. The mean induction-establishment and induction-delivery intervals were 4.3 +/- 0.1 min and 6.07 +/- 1.7 h, respectively. The control group showed no response. PGE2 cervical injection is a safe and effective method for cervical ripening and labor induction.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria University, Egypt.
authors.forename: S
authors.initials: S
authors.lastname: Shaala
authors.forename: E
authors.initials: E
authors.lastname: Darwish
authors.forename: M
authors.initials: M
authors.lastname: Anwar
authors.forename: M
authors.initials: M
authors.lastname: Rocca
authors.forename: A A
authors.initials: AA
authors.lastname: Ismail
mesh_terms: D000328:Adult; D002584:Cervix Uteri; D005260:Female; D006801:Humans; D007267:Injections / Q000379:methods; D007751:Labor, Induced / Q000379:methods*; D010298:Parity; D011247:Pregnancy; D011459:Prostaglandins E, Synthetic / Q000008:administration & dosage*
chemical_list: D011459:Prostaglandins E, Synthetic