Sjögren's syndrome: association with type-1 diabetes mellitus.
This study of 102 unselected type-1 diabetic patients has shown that sicca symptoms affect 55% of the patients, although sometimes only during hyperglycaemic phases. While these symptoms might be attributable to the diabetes, the frequency of antinuclear antibodies in those suspected of having Sjögren's (25% by HEp-2) and particularly anti-Ro antibodies (32% by ELISA) reinforces the suspicion that Sjögren's syndrome may underlie their presence.
Binder
A
A
Bloomsbury Rheumatology Unit, University College, London.
Maddison
P J
PJ
Skinner
P
P
Kurtz
A
A
Isenberg
D A
DA
D000293:Adolescent; D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D005260:Female; D006801:Humans; D006943:Hyperglycemia; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology
D000974:Antibodies, Antinuclear