title: Diabetes insipidus caused by lymphocytic infundibuloneurohypophysitis.
abstract: Pathologic examination at autopsy of a 74-year-old man with central diabetes insipidus revealed that he had a chronic lymphocytic inflammation limited to the infundibulum, stalk, and posterior lobe of the pituitary gland. No meningitis, sarcoidosis, or granulomas were detected, though there was evidence of chronic pancreatitis. In addition, neuronal loss with gliosis was observed bilaterally in the supraoptic and paraventricular nuclei. The unusual localized inflammatory brain lesion was considered to be responsible for the diabetes insipidus.
authors.affiliation: Department of Pathology, Hokkaido University School of Medicine, Sapporo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kojima
authors.forename: T
authors.initials: T
authors.lastname: Nojima
authors.forename: K
authors.initials: K
authors.lastname: Nagashima
authors.forename: Y
authors.initials: Y
authors.lastname: Ono
authors.forename: M
authors.initials: M
authors.lastname: Kudo
authors.forename: M
authors.initials: M
authors.lastname: Ishikura
mesh_terms: D000368:Aged; D003919:Diabetes Insipidus / Q000209:etiology*; D006801:Humans; D007249:Inflammation / Q000150:complications / Q000473:pathology; D008297:Male; D010195:Pancreatitis / Q000209:etiology; D010900:Pituitary Diseases / Q000150:complications* / Q000473:pathology; D010902:Pituitary Gland / Q000473:pathology