Is chronic sunlight exposure important in accounting for increases in melanoma incidence?
Most attempts to relate changes in patterns of sunlight exposure to the rise in incidence of malignant melanoma have concentrated on the positive association between intermittent exposure to sunlight and risk of melanoma. The Western Canada Melanoma Study, however, also detected a significant inverse association between melanoma and chronic or long-term occupational sun exposure in men, with the lowest risk (OR = 0.5) in those with maximum occupational exposure, suggesting that chronic exposure may be protective. Data obtained from Canadian census figures indicated that since 1951 there has been a substantial reduction in the number of males engaged in outdoor occupations in Canadian society. These observations suggest that part of the increase in the incidence of melanoma in low-sunlight areas may be due to a reduction over the past 40 years of the size of this group of individuals "protected" by their exposure to UV light.
Gallagher
R P
RP
Division of Epidemiology, Biometry and Occupational Oncology, Cancer Control Agency of British Columbia, Vancouver, Canada.
Elwood
J M
JM
Yang
C P
CP
D002170:Canada; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008545:Melanoma / Q000453:epidemiology / Q000209:etiology*; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D009784:Occupational Diseases / Q000209:etiology; D012307:Risk Factors; D013472:Sunlight; D013997:Time Factors