title: Cells of origin of histaminergic afferents to the cat median eminence.
abstract: The exact origin of histaminergic neuronal perikarya sending axons to the median eminence and posterior pituitary was investigated in the cat by using two colour double-immunostaining methods: unconjugated wheat germ agglutinin or cholera toxin as retrograde tracers combined with histamine (HA) immunohistochemistry. HA immunohistochemistry revealed the presence of HA-immunoreactive terminal-like fibers both in the external layer of the median eminence and neural lobe of the pituitary. The double-labeling studies further demonstrated the histaminergic innervation of the median eminence and neural lobe by a few HA-immunoreactive neuronal perikarya located in the posterior hypothalamus.
authors.affiliation: Departement de Médecine Expérimentale, INSERM U 52, CNRS UA 1195, Université Claude Bernard, Lyon, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Yoshimoto
authors.forename: K
authors.initials: K
authors.lastname: Sakai
authors.forename: P
authors.initials: P
authors.lastname: Panula
authors.forename: D
authors.initials: D
authors.lastname: Salvert
authors.forename: M
authors.initials: M
authors.lastname: Stuart
authors.forename: M
authors.initials: M
authors.lastname: Jouvet
mesh_terms: D000818:Animals; D002415:Cats; D006632:Histamine / Q000378:metabolism*; D007031:Hypothalamus / Q000378:metabolism*; D007034:Hypothalamus, Posterior / Q000166:cytology / Q000378:metabolism*; D007150:Immunohistochemistry; D008473:Median Eminence / Q000166:cytology / Q000378:metabolism*; D010904:Pituitary Gland, Posterior / Q000166:cytology / Q000378:metabolism*; D014909:Wheat Germ Agglutinins
chemical_list: D014909:Wheat Germ Agglutinins; D006632:Histamine