Comparison of diurnal and nocturnal rates of 5-hydroxytryptamine turnover in the rat mediobasal hypothalamus.
Rates of 5-hydroxytryptamine (5-HT) turnover in the mediobasal hypothalamus of male rats were estimated using pharmacological methods during the daytime and at night. Concentrations of 5-HT in this hypothalamic area were higher nocturnally than diurnally; this was apparently due to increased 5-HT synthesis and decreased 5-HT catabolism at night.
King
T S
TS
Steinlechner
S
S
Steger
R W
RW
D006916:5-Hydroxytryptophan / Q000378:metabolism; D000818:Animals; D002940:Circadian Rhythm; D006834:Hydrazines / Q000494:pharmacology; D006897:Hydroxyindoleacetic Acid / Q000378:metabolism; D007033:Hypothalamus, Middle / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D010293:Pargyline / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000378:metabolism*
D006834:Hydrazines; D012701:Serotonin; D006897:Hydroxyindoleacetic Acid; D010293:Pargyline; C004297:3-hydroxybenzylhydrazine; D006916:5-Hydroxytryptophan