title: Estimation of the relative bioavailability of manganese sources for sheep.
abstract: The relative biological availability of Mn in reagent-grade (RG) Mn sources was tested using 41 Rambouillet crossbred wether lambs in a completely randomized design. Lambs were fed a basal corn-soybean meal-cottonseed hull diet (37.6 ppm Mn, DM basis) or this basal diet supplemented with 0, 1,500, 3,000 or 4,500 ppm Mn from RG MnSO4.H20 or 3,000 ppm Mn from RG MnO, MnO2 and MnCO3. Feed intake was restricted to 1,000 g/hd daily during the 21-d experimental period. There was a decrease (P less than .01) in daily feed intake by sheep fed 4,500 ppm Mn from MnSO4. Liver, kidney and bone Mn concentrations increased (P less than .05) with MnSO4 supplementation. Liver was most responsive to dietary Mn, followed by kidney and bone. Based on multiple linear regression slopes for liver, kidney and bone Mn concentrations, relative bioavailability of Mn from MnO, MnO2 and MnCO3 averaged 57.7, 32.9 and 27.8%, compared with 100% for MnSO4.
authors.affiliation: University of Florida, Gainesville 32611.
authors.forename: J
authors.initials: J
authors.lastname: Wong-Valle
authors.forename: P R
authors.initials: PR
authors.lastname: Henry
authors.forename: C B
authors.initials: CB
authors.lastname: Ammerman
authors.forename: P V
authors.initials: PV
authors.lastname: Rao
mesh_terms: D000821:Animal Feed; D000818:Animals; D001682:Biological Availability; D001842:Bone and Bones / Q000378:metabolism; D002254:Carbonates; D004435:Eating; D007668:Kidney / Q000378:metabolism; D016014:Linear Models; D008099:Liver / Q000378:metabolism; D008297:Male; D008345:Manganese / Q000493:pharmacokinetics*; D017895:Manganese Compounds; D010087:Oxides; D011897:Random Allocation; D012044:Regression Analysis; D012756:Sheep / Q000378:metabolism*; D013431:Sulfates / Q000493:pharmacokinetics
chemical_list: D002254:Carbonates; D017895:Manganese Compounds; D010087:Oxides; D013431:Sulfates; D008345:Manganese; C027424:manganese oxide; C045327:manganese carbonate; C016552:manganese dioxide; C039798:manganese sulfate