title: Regional localization of the sperm-specific lactate dehydrogenase, LDHC, gene on human chromosome 11.
abstract: A cDNA clone complementary to the mRNA encoding the sperm-specific lactate dehydrogenase, LDHC, has been used to map the LDHC locus to the short arm of human chromosome 11. In situ hybridization data and analysis of mouse/human somatic cell hybrids carrying deletions of human chromosome 11 suggest that the gene is localized at p15.3-p15.5 close to the LDHA gene.
authors.affiliation: MRC Human Biochemical Genetics Unit, Galton Laboratory, University College London.
authors.forename: Y
authors.initials: Y
authors.lastname: Edwards
authors.forename: L
authors.initials: L
authors.lastname: West
authors.forename: V
authors.initials: V
authors.lastname: Van Heyningen
authors.forename: J
authors.initials: J
authors.lastname: Cowell
authors.forename: E
authors.initials: E
authors.lastname: Goldberg
mesh_terms: D000818:Animals; D002460:Cell Line; D002874:Chromosome Mapping; D002880:Chromosomes, Human, Pair 11; D004247:DNA / Q000235:genetics; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000235:genetics*; D008297:Male; D051379:Mice; D009693:Nucleic Acid Hybridization; D015183:Restriction Mapping; D013094:Spermatozoa / Q000201:enzymology*
chemical_list: D004247:DNA; D007770:L-Lactate Dehydrogenase