title: Central nervous system acute promyelocytic leukaemia: a report of three cases.
abstract: Authors report 3 cases of acute promyelocytic leukaemia, in which the central nervous system was involved in the first period of relapse. The clinical features of these patients are discussed. Authors conclude that central nervous system involvement in acute promyelocytic leukaemia must be considered a very bad prognostic sign, because in these cases a rapidly progressive course may be expected.
authors.affiliation: Istituto di Semeiotica Medica, Universita Cattolica S. Cuore Roma, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Marra
authors.forename: S
authors.initials: S
authors.lastname: Stori
authors.forename: L
authors.initials: L
authors.lastname: Pagano
authors.forename: G
authors.initials: G
authors.lastname: Fioritoni
authors.forename: C
authors.initials: C
authors.lastname: Rabitti
authors.forename: S
authors.initials: S
authors.lastname: Sica
authors.forename: G
authors.initials: G
authors.lastname: Leone
authors.forename: G
authors.initials: G
authors.lastname: Torlontano
authors.forename: B
authors.initials: B
authors.lastname: Bizzi
mesh_terms: D001856:Bone Marrow Examination; D001932:Brain Neoplasms / Q000134:cerebrospinal fluid / Q000473:pathology*; D002493:Central Nervous System Diseases / Q000134:cerebrospinal fluid* / Q000473:pathology; D005260:Female; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000134:cerebrospinal fluid* / Q000473:pathology; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology*; D008875:Middle Aged; D012008:Recurrence