title: Biological profile of a virus belonging to California encephalitis complex isolated in Karelian Autonomous Soviet Socialist Republic.
abstract: We investigated in white mice and in Syrian hamsters the pathogenesis of infection with a virus belonging to the California encephalitis complex isolated in the Karelian Autonomous Soviet Socialist Republic. The pathogenic properties of the virus were investigated also in green monkeys. The localization and character of lesions in the organs of given animals appeared to be similar. The virus appeared to possess neurotropic activity, it propagated in the animal body by haematogenous route. The virus was found to be heat-resistant and pH-sensitive.
authors.affiliation: D. I. Ivanovsky Institute of Virology, U.S.S.R., Academy of Medical Sciences, Moscow.
authors.forename: D K
authors.initials: DK
authors.lastname: Lvov
authors.forename: L N
authors.initials: LN
authors.lastname: Abramova
authors.forename: N S
authors.initials: NS
authors.lastname: Savosina
authors.forename: I I
authors.initials: II
authors.lastname: Terskikh
authors.forename: T M
authors.initials: TM
authors.lastname: Skvortsova
authors.forename: V L
authors.initials: VL
authors.lastname: Gromashevsky
mesh_terms: D000818:Animals; D002043:Bunyaviridae / Q000302:isolation & purification*; D002522:Chlorocebus aethiops; D006224:Cricetinae; D002141:Encephalitis Virus, California / Q000302:isolation & purification* / Q000472:pathogenicity; D004670:Encephalitis, California / Q000209:etiology / Q000473:pathology; D008647:Mesocricetus; D051379:Mice; D009928:Organ Specificity; D014586:USSR