title: Localization of two alkaline phosphatase genes to the proximal region of mouse chromosome 1.
abstract: Using a human cDNA clone encoding the intestinal form of alkaline phosphatase, we have identified and mapped by RFLP analysis in a Mus spretus x C57BL/6J interspecies backcross two alkaline phosphatase genes which segregate independently on the proximal part of mouse Chromosome 1. The gene order and intergene distances were determined by standard backcross analysis as: centromere- Len-2 - 19.0 cM - Akp-3 - 20.0 cM - Akp-4 - 2.0 cM - Ren-1.
authors.affiliation: Department of Biochemistry, McGill University, Montreal, Quebec, Canada.
authors.forename: E
authors.initials: E
authors.lastname: Schurr
authors.forename: P S
authors.initials: PS
authors.lastname: Henthorn
authors.forename: H
authors.initials: H
authors.lastname: Harris
authors.forename: E
authors.initials: E
authors.lastname: Skamene
authors.forename: P
authors.initials: P
authors.lastname: Gros
mesh_terms: D000469:Alkaline Phosphatase / Q000235:genetics*; D000818:Animals; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D015342:DNA Probes; D006801:Humans; D051379:Mice; D008810:Mice, Inbred C57BL; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D015342:DNA Probes; D000469:Alkaline Phosphatase