title: Growth and development in thanatophoric dysplasia.
abstract: Two cases of prolonged survival of thanatophoric dysplasia are presented, in which ventilatory support was initiated in the neonatal period because of respiratory distress. Both patients required a ventriculoperitoneal shunt for hydrocephalus and had decompression of the posterior fossa. The history of each patient has been characterized by profound developmental delay and dramatic growth failure.
authors.affiliation: Department of Ophthalmology, Childrens' Hospital of Eastern Ontario, Ottawa, Canada.
authors.forename: I M
authors.initials: IM
authors.lastname: MacDonald
authors.forename: A G
authors.initials: AG
authors.lastname: Hunter
authors.forename: P M
authors.initials: PM
authors.lastname: MacLeod
authors.forename: S B
authors.initials: SB
authors.lastname: MacMurray
mesh_terms: D001132:Arm / Q000000981:diagnostic imaging; D001827:Body Height; D001835:Body Weight; D001846:Bone Development; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006849:Hydrocephalus; D007866:Leg / Q000000981:diagnostic imaging; D008297:Male; D010009:Osteochondrodysplasias / Q000503:physiopathology*; D011859:Radiography; D013131:Spine / Q000000981:diagnostic imaging; D013796:Thanatophoric Dysplasia / Q000503:physiopathology*