The generalized equation for the radiotracer clearance method of measurement of regional microcirculation.
The intratissual diffusion of a tracer and the geometry of the detection system are considered and a generalization of Kety's equation for the measurement of regional microcirculation is derived. Non-monoexponential shapes of time-activity curves are examined and explained.
Szczesny
S
S
Silesian Medical Academy, Department of Biophysics, K. Marksa, Poland.
Turczyński
B
B
D006801:Humans; D008433:Mathematics; D008833:Microcirculation; D008955:Models, Cardiovascular; D011868:Radioisotopes / Q000493:pharmacokinetics*; D012039:Regional Blood Flow
D011868:Radioisotopes