A randomized trial of iohexol versus amidotrizoate in endoscopic retrograde pancreatography.
To evaluate whether a low-osmolar contrast medium could decrease hyperamylasemia after endoscopic retrograde pancreatography, a prospective randomized double-blind trial of 54 consecutive patients with suspected pancreatic disease referred for endoscopic retrograde pancreatography was performed. The low-osmolar contrast medium iohexol and high-osmolar amidotrizoate were used. No statistically significant differences with regard to rise in pancreatic-type amylase, pain reaction, or diagnostic information were found. No case of acute pancreatitis was observed.
Jensen
A R
AR
Malchow-Møller
A
A
Matzen
P
P
Larsen
J E
JE
Møller
F
F
Andersen
J R
JR
Magid
E
E
D000328:Adult; D000681:Amylases / Q000097:blood*; D002760:Cholangiopancreatography, Endoscopic Retrograde; D002769:Cholelithiasis / Q000000981:diagnostic imaging; D002986:Clinical Trials as Topic; D003973:Diatrizoate / Q000009:adverse effects; D004311:Double-Blind Method; D006801:Humans; D007463:Iodobenzoates; D007472:Iohexol; D010182:Pancreatic Diseases / Q000000981:diagnostic imaging; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging; D011446:Prospective Studies; D011897:Random Allocation; D014283:Triiodobenzoic Acids / Q000009:adverse effects
D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D003973:Diatrizoate; D007472:Iohexol; D000681:Amylases