Goodpasture's syndrome in a patient with two endocrine tumours.
We describe the occurrence of two anatomically separate and histologically distinct endocrine tumours of bronchus and pancreas in a 64 year old woman with biopsy and serology proven Goodpasture's syndrome. The association between anti-glomerular basement membrane antibody disease and multiple endocrine tumours has not been reported previously; possible pathogenetic mechanisms are discussed.
McMahon
R F
RF
Department of Pathology, University of Manchester, UK.
Lawler
W
W
O'Donoghue
D J
DJ
Ballardie
F W
FW
D007516:Adenoma, Islet Cell / Q000150:complications; D019867:Anti-Glomerular Basement Membrane Disease / Q000150:complications*; D001706:Biopsy; D001984:Bronchial Neoplasms / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D008875:Middle Aged; D009377:Multiple Endocrine Neoplasia / Q000150:complications* / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000473:pathology