[Experimental study of embolo-hyperthermia for treatment of liver tumor--induction heating to ferromagnetic particles injected into tumor tissue].
Hepatic arterial embolization was performed on VX2 liver tumor of rabbit with subsequent induction heating to the tumor. Prior to the heating, iron particle suspension was injected into tumor tissue as a target of induction heating (500 KHZ, 9 KW). The temperatures of the tumor and liver parenchyma were measured with fluoroptic thermometer. Elevation of the tumor temperature during initial heating for 6 minutes were well correlated to the dose of iron particles injected; 1.4 degrees C with 1 g, 3.0 degrees C with 2 g, and 4.9 degrees C with 3 g. The temperature of liver parenchyma were below 39 degrees C even with 3 g injection.
Hase
M
M
Sako
M
M
Fujii
M
M
Ueda
E
E
Nagae
T
T
Shimizu
T
T
Hirota
S
S
Kono
M
M
D000818:Animals; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic; D006979:Hyperthermia, Induced; D008114:Liver Neoplasms, Experimental / Q000628:therapy*; D008280:Magnetics; D008297:Male; D011817:Rabbits