[10 families with benign familial hematuria. Considerations on prevalence, genetics and clinical and urine characteristics].
We studied 10 families in which 115 members showed isolated microscopic hematuria without nephritis and impairment of renal function. All the affected members were completely asymptomatic and normal on physical and laboratory examination and therefore diagnosis of benign familial hematuria (BFH) was made. In these families BFH was inherited as an autosomal dominant trait with incomplete penetrance and variable expressivity. A linkage between BFH and ABO and Rh genes was excluded.
Li Volti
S
S
D'Avola
M A
MA
Mollica
F
F
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005190:Family; D005192:Family Health; D005260:Female; D006417:Hematuria / Q000150:complications / Q000453:epidemiology / Q000235:genetics* / Q000652:urine; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D015995:Prevalence
Studio di 10 famiglie con ematuria familiare benigna. Considerazioni sulla prevalenza, sulla genetica e sulle caratteristiche cliniche ed urinarie.