title: [Primary myxedema in an adult. Notes on a case].
abstract: In the case of adult primary myxedema reported the diagnostic suspicion aroused by objective examination was confirmed by assaying the hypophysial-thyroid hormones (blood T4 and T3 below normal levels) and by the behaviour of certain muscle enzymes (CPK, LDH, GOT) that bore witness to diffuse muscle and bone damage (hypothyroid "myopathy"). The presence of antithyroid antibodies, though in small amounts suggested earlier and unnoticed thyroiditis as a possible aetiopathogenic explanation. The clinical and metabolic picture undoubtedly benefited from treatment with L-Thyroxine.
authors.affiliation: Regione Toscana - U.S.L. Presidio Ospedaliero di Castel del Piano.
authors.forename: R
authors.initials: R
authors.lastname: Monaci
authors.forename: S
authors.initials: S
authors.lastname: Meoni
authors.forename: M
authors.initials: M
authors.lastname: Morandini
authors.forename: G
authors.initials: G
authors.lastname: Giacalone
authors.forename: C
authors.initials: C
authors.lastname: Bernardini
authors.forename: F
authors.initials: F
authors.lastname: Pii
mesh_terms: D001219:Aspartate Aminotransferases / Q000097:blood; D004796:Clinical Enzyme Tests; D003402:Creatine Kinase / Q000097:blood; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000201:enzymology; D009230:Myxedema / Q000175:diagnosis / Q000188:drug therapy; D013974:Thyroxine / Q000097:blood / Q000627:therapeutic use; D014284:Triiodothyronine / Q000097:blood
chemical_list: D014284:Triiodothyronine; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D003402:Creatine Kinase; D013974:Thyroxine
vernacular_title: Mixedema primitivo dell'adulto. Osservazioni su un caso.