title: Auto-erythrocyte sensitisation--the Gardner-Diamond syndrome. A case report.
abstract: A 34-year-old woman with a 3-year history of easy bruising of unexplained aetiology in anatomical sites consistent with self-infliction is described. Despite major surgery, the patient had never experienced inappropriate bleeding. Owing to psychological instability, the possibility of auto-erythrocyte sensitisation was considered; this was confirmed by subcutaneous injection of autologous red cells and haemolysate, which caused local tenderness and induration. This manifestation of Gardner-Diamond syndrome is unusual and is reported to draw attention to its existence and perhaps thereby avoid unnecessary and costly investigations.
authors.affiliation: University of Cape Town Leukaemia Centre.
authors.forename: J M
authors.initials: JM
authors.lastname: Du Toit
authors.forename: P
authors.initials: P
authors.lastname: Jacobs
authors.forename: A R
authors.initials: AR
authors.lastname: Bird
authors.forename: D N
authors.initials: DN
authors.lastname: Dickson
mesh_terms: D000328:Adult; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D011693:Purpura / Q000209:etiology*; D013577:Syndrome
chemical_list: D007136:Immunoglobulins