[Analysis of the interconnection between susceptibility factors to schizophrenia and epilepsy].
The results of the genetic-correlative analysis of schizophrenia (681 families) and epilepsy (365 families) are given. The presence of various liabilities to these diseases, having genetic correlation of 0.16-0.19 between them, is shown. From epidemiologic data, elevated frequency of convulsive manifestations in schizophrenics and schizophrenia-like psychosis in epileptic patients was established. Within the limits of the three-component hypothesis of etiology of these diseases ("major genes", environmental factors and constitutional readiness), the relation detected is explained by interaction between constitutional readiness factors.
Ritsner
M S
MS
D004198:Disease Susceptibility; D004827:Epilepsy / Q000235:genetics*; D006801:Humans; D008957:Models, Genetic; D012559:Schizophrenia / Q000235:genetics*
Analiz vzaimosviazi mezhdu faktorami podverzhennosti shizofrenii i épilepsii.