[Clinical research of specific IgE and IgG4 antibody in allergic children. Correlation specific IgE antibody to specific IgG4 antibody to food allergen].
We analysed the correlation specific IgE antibodies to specific IgG4 antibodies to food allergens in 150 asthmatic children by Multiple Factor Analysis-Type II and examined the role of both antibodies. The following results were obtained. 1) Of soybean, there was the stronger influence power between specific IgE and IgG4 antibody than the other 2 food allergens. 2) IgE antibody to soybean had the strong influence power to IgG4 antibodies to egg white and cow's milk and IgG4 antibody to soybean had same influence power to IgE antibodies to egg white and cow's milk. So, the specific IgE and IgG4 antibodies to soybean may be play the role of "the bride" between specific IgE antibody group and specific IgG4 antibody group of food allergens.
Koya
N
N
Suzuki
S
S
Hara
M
M
Nagata
K
K
Tateno
A
A
Moroi
T
T
Iikura
Y
Y
D000293:Adolescent; D000918:Antibody Specificity; D001249:Asthma / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D005163:Factor Analysis, Statistical; D005260:Female; D005512:Food Hypersensitivity / Q000276:immunology*; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D008297:Male
D007074:Immunoglobulin G; D007073:Immunoglobulin E