Percutaneous absorption of 3 organic solvents in the guinea pig (IV). Effect of protective gloves.
The efficacy of 3 protective glove materials against percutaneous absorption of organic solvents was investigated in the guinea pig. All 3 materials gave a reduction in blood concentration of the solvents, particularly in the early phase of exposure. Of the tested materials, butyl rubber showed the best protective effect, followed by PVC and natural rubber. Gloves of polymeric material can be considered as offering sufficient protection against percutaneous absorption of organic solvents only if their selection is based on results obtained in a controlled and adequately performed test.
Boman
A
A
Department of Occupational Dermatology, National Institute of Occupational Health, Solna, Sweden.
Mellström
G
G
D020001:1-Butanol; D000818:Animals; D000440:Butanols / Q000493:pharmacokinetics; D005260:Female; D006168:Guinea Pigs; D011143:Polyvinyl Chloride; D011481:Protective Clothing; D012408:Rubber; D012869:Skin Absorption; D012997:Solvents / Q000493:pharmacokinetics*; D014050:Toluene / Q000493:pharmacokinetics; D014240:Trichloroethanes / Q000493:pharmacokinetics
D000440:Butanols; D012997:Solvents; D014240:Trichloroethanes; C024566:1,1,1-trichloroethane; D014050:Toluene; D020001:1-Butanol; D011143:Polyvinyl Chloride; D012408:Rubber