title: Generation of new bone around titanium implants using a membrane technique: an experimental study in rabbits.
abstract: Insufficient bone volume may be a significant problem in connection with dental implants. In this study, a technique based on the principle of guided tissue regeneration was tested for its ability to generate bone tissue around titanium implants. Implants were inserted in tibiae of rabbits. To create a secluded space for osteogenesis and to prevent soft-tissue ingrowth, a porous Teflon membrane was placed around exposed parts of the implant. Where a membrane had been used, the threads of the implant were completely covered with significant amounts of new bone. This study indicates that the membrane technique is a reconstructive surgical method that may be applicable to create new bone around exposed parts of titanium implants in a clinical setting.
authors.forename: C
authors.initials: C
authors.lastname: Dahlin
authors.forename: L
authors.initials: L
authors.lastname: Sennerby
authors.forename: U
authors.initials: U
authors.lastname: Lekholm
authors.forename: A
authors.initials: A
authors.lastname: Linde
authors.forename: S
authors.initials: S
authors.lastname: Nyman
mesh_terms: D000818:Animals; D001861:Bone Regeneration; D003758:Dental Implantation, Endosseous / Q000379:methods*; D008567:Membranes, Artificial; D011138:Polytetrafluoroethylene; D011817:Rabbits; D014025:Titanium
chemical_list: D008567:Membranes, Artificial; D011138:Polytetrafluoroethylene; D014025:Titanium