title: Hypothesis: interference with axonal transport of neurofilament as a common pathogenetic mechanism in certain diseases of the central nervous system.
authors.forename: D C
authors.initials: DC
authors.lastname: Gajdusek
mesh_terms: D000544:Alzheimer Disease / Q000473:pathology; D000690:Amyotrophic Lateral Sclerosis / Q000209:etiology; D000818:Animals; D001323:Autoantibodies / Q000032:analysis; D001370:Axonal Transport; D002470:Cell Survival; D002493:Central Nervous System Diseases / Q000209:etiology* / Q000378:metabolism; D007562:Creutzfeldt-Jakob Syndrome / Q000276:immunology; D003599:Cytoskeleton / Q000276:immunology / Q000378:metabolism*; D003704:Dementia / Q000209:etiology; D006801:Humans; D006882:Hydroxyapatites / Q000378:metabolism; D007729:Kuru / Q000276:immunology; D008670:Metals / Q000378:metabolism; D009046:Motor Neurons / Q000473:pathology; D009419:Nerve Tissue Proteins / Q000378:metabolism; D009454:Neurofibrils / Q000473:pathology; D009474:Neurons / Q000378:metabolism; D010302:Parkinson Disease, Secondary / Q000209:etiology; D012608:Scrapie / Q000276:immunology; D012756:Sheep; D014713:Viruses, Unclassified / Q000502:physiology
chemical_list: D001323:Autoantibodies; D006882:Hydroxyapatites; D008670:Metals; D009419:Nerve Tissue Proteins