title: Microcomputer system for ion microscopy digital imaging and processing.
abstract: Analytical ion microscopy is a powerful tool for biological tissue analysis as it allows direct chemical distribution imaging, even at low element concentrations. A microcomputer based digital imaging system achieving acquisition at low light level is presented. It includes a high sensitivity video camera connected to a specialized image processor subsystem. Acquired images consist of 512 x 512 pixels with 8 bits accuracy. Real-time image processing software has been implemented so that image processing may be performed on-line. Image processing software allows off-line image manipulation and correlation for biological interpretation of elemental mapping images. System capabilities are illustrated by a study of stable and radio iodine mapping in rat thyroid tissue.
authors.affiliation: INSERM U-66, Institut Gustave Roussy, Villejuif, France.
authors.forename: J C
authors.initials: JC
authors.lastname: Olivo
authors.forename: E
authors.initials: E
authors.lastname: Kahn
authors.forename: S
authors.initials: S
authors.lastname: Halpern
authors.forename: C
authors.initials: C
authors.lastname: Briancon
authors.forename: P
authors.initials: P
authors.lastname: Fragu
authors.forename: R
authors.initials: R
authors.lastname: DiPaola
mesh_terms: D000465:Algorithms; D000818:Animals; D007091:Image Processing, Computer-Assisted; D013058:Mass Spectrometry; D008838:Microcomputers; D051381:Rats; D012984:Software; D013961:Thyroid Gland / Q000033:anatomy & histology*