Macromelanosomes in X-linked ocular albinism (XLOA).
A case of X-linked ocular albinism is reported. Characteristic Masson-Fontana positive and Dopa positive giant melanin granules were found in keratinocytes, melanocytes and upper dermis. Ultrastructurally the macromelanosome was composed of a dense core and a less dense surrounding mantle.
Yoshiike
T
T
Manabe
M
M
Hayakawa
M
M
Ogawa
H
H
D000328:Adult; D000417:Albinism / Q000235:genetics* / Q000473:pathology; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D005127:Eye Color; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D008297:Male; D008543:Melanins / Q000378:metabolism; D008544:Melanocytes / Q000648:ultrastructure*; D008854:Microscopy, Electron; D012729:Sex Chromosome Aberrations / Q000235:genetics* / Q000473:pathology; D012867:Skin / Q000473:pathology; D014960:X Chromosome
D008543:Melanins