[Effect of the combined action of cadmium and ethyl alcohol or cadmium and acetaldehyde on the genesis of sister chromatid exchange in lymphocytes of human blood in vitro].
The frequency of exchange of sister chromatids was studied in vitro in peripheral blood lymphocytes of three healthy donors. Mixtures: 3.1 X 10(-3) mM of cadmium sulphate and 43.4 mM of ethanol or 6.2 X 10(-3) mM of cadmium sulphate and 43.4 mM of ethanol or 6.2 X 10(-3) mM of cadmium sulphate and 43.4 mM of ethanol increased significantly the number of these exchanges in only one donor. Mixtures of 0.18 mM of acetaldehyde with cadmium sulphate in three concentrations: 1.6 X 10(-3) mM, 3.2 X 10(-3) mM and 6.2 X 10(-3) mM increased significantly the frequency of exchanges in all donors.
Bassendowska-Karska
E
E
Zawadzka-Kos
M
M
D000079:Acetaldehyde / Q000494:pharmacology*; D002104:Cadmium / Q000494:pharmacology*; D004357:Drug Synergism; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000187:drug effects*; D012854:Sister Chromatid Exchange / Q000187:drug effects*
D002104:Cadmium; D000431:Ethanol; D000079:Acetaldehyde
Wpływ skojarzonego działania kadmu i alkoholu etylowego oraz kadmu i aldehydu octowego na powstawanie wymian siostrzanych chromatyd w limfocytach krwi ludzi w warunkach in vitro.