[Systemic or intracerebral injection of bovine neurointermediate lobe extracts may induce paradoxical sleep in insomnia induced by p-chlorophenylalanine in cats].
Injections of Bovine neuro-intermediate lobe extracts, either subcutaneously (5 U), intraventricularly (20 mU) or directly in the vicinity of the nucleus magnocellularis of the medulla (1,3 mU) may induce paradoxical sleep in totally insomniac cats pretreated with P. chlorophenylalanine.
Sastre
J P
JP
Buda
C
C
Janin
M
M
Seguin
S
S
Sallanon
M
M
Jouvet
M
M
D000818:Animals; D002415:Cats; D010134:Fenclonine; D006801:Humans; D007276:Injections, Intraventricular; D007279:Injections, Subcutaneous; D010902:Pituitary Gland / Q000502:physiology*; D010904:Pituitary Gland, Posterior / Q000502:physiology; D007319:Sleep Initiation and Maintenance Disorders / Q000139:chemically induced / Q000503:physiopathology*; D012895:Sleep, REM / Q000502:physiology*; D013373:Substance P / Q000502:physiology; D014020:Tissue Extracts / Q000494:pharmacology*
D014020:Tissue Extracts; D013373:Substance P; D010134:Fenclonine
L'injection systémique ou intracérébrale d'extraits de lobe neuro-intermédiaire de Boeuf peut induire le sommeil paradoxal au cours de l'insomnie provoquée par la P. chlorophénylalanine chez le chat.