Cell-mediated immune response to Coxiella burnetii antigens in Q fever convalescents and vaccinees.
Cellular immunity against phase I and II Coxiella burnetii antigens was evaluated by the lymphocyte blast transformation test in a) Q fever convalescents; b) persons immunized with a chemovaccine against Q fever; and c) control persons. The first two groups consisted of workers in a ricketsiology department. Of the 9 convalescents, all (100%) were positive against phase I antigen and 4 (44.4%) against phase II antigen. Of the 22 vaccinees, 77.3% were positive against phase I antigen and all were negative against phase II antigen. All 10 controls were negative against both antigens.
Gajdosová
E
E
Institute of Virology, Slovak Academy of Sciences, Bratislava, Czechoslovakia.
Brezina
R
R
D000942:Antigens, Bacterial / Q000276:immunology; D003289:Convalescence; D003381:Coxiella / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology; D008213:Lymphocyte Activation / Q000276:immunology; D011778:Q Fever / Q000276:immunology* / Q000628:therapy; D012882:Skin Tests; D014611:Vaccination
D000942:Antigens, Bacterial