title: Lack of association between scleroderma and types I and III procollagen gene restriction fragment length polymorphisms.
abstract: Restriction fragment length polymorphisms (RFLPs) in types I and III procollagen genes were studied in 62 scleroderma patients and 138 healthy controls. Allelic frequencies were determined for each RFLP, and comparisons were made between the 2 populations, stratifying them by race when appropriate. No statistically significant differences were observed for the frequencies of any of the RFLPs studied.
authors.affiliation: Department of Obstetrics and Gynecology, University of Maryland School of Medicine, Baltimore 21201.
authors.forename: L E
authors.initials: LE
authors.lastname: Kratz
authors.forename: J A
authors.initials: JA
authors.lastname: Boughman
authors.forename: B W
authors.initials: BW
authors.lastname: Needleman
mesh_terms: D000483:Alleles; D044383:Black People / Q000235:genetics; D005796:Genes; D006801:Humans; D012150:Polymorphism, Restriction Fragment Length; D011347:Procollagen / Q000235:genetics*; D012595:Scleroderma, Systemic / Q000235:genetics*; D044465:White People / Q000235:genetics
chemical_list: D011347:Procollagen