Massive pulmonary hemorrhage in mixed connective tissue diseases.
We report a patient with mixed connective tissue disease (MCTD) who suddenly developed pulmonary distress with bilateral pulmonary infiltrates. She died in 24 h and was found at necropsy to have had a massive alveolar hemorrhage, as well as renal necrotizing vasculitis and immune complex deposits in the glomeruli. One previous case of MCTD with pulmonary hemorrhage was found in the literature. Recognition of this complication of MCTD may help in its early diagnosis.
Sanchez-Guerrero
J
J
Department of Immunology and Rheumatology, Instituto Nacional de la Nutrición, Salvador Zubirán, Mexico City, Mexico.
Cesarman
G
G
Alarcón-Segovia
D
D
D000328:Adult; D005260:Female; D006469:Hemoptysis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008168:Lung / Q000473:pathology; D008947:Mixed Connective Tissue Disease / Q000150:complications* / Q000473:pathology; D011650:Pulmonary Alveoli / Q000473:pathology