title: Effects of two gutta-percha formulations and one zinc oxide-eugenol and Canada balsam mixture on human blood monocytes and lymphocytes.
abstract: In this study we performed an in vitro assay of the effects of two gutta-percha formulations and one zinc oxide-eugenol and Canada balsam-based endodontic material on the behavior of a mixed cell population of human monocytes and lymphocytes. Cells were cultured either in direct contact with or near experimental samples of Ultrafil, standard gutta-percha cones or Endoseal and the inhibitory effects of these materials upon cell attachment and spreading on test surfaces were analyzed. Ultrafil and the standard gutta-percha cones showed little or no adverse effects, whereas the inhibitory effects of Endoseal appeared to be severe. There were statistically significant differences between the results obtained from both Ultrafil and gutta-percha cones and those obtained from Endoseal. Differences between all tested materials and their respective controls were also statistically significant.
authors.forename: O
authors.initials: O
authors.lastname: Zmener
authors.forename: F
authors.initials: F
authors.lastname: Goldberg
authors.forename: R L
authors.initials: RL
authors.lastname: Cabrini
mesh_terms: D001453:Balsams / Q000633:toxicity*; D006171:Gutta-Percha / Q000633:toxicity*; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects*; D009000:Monocytes / Q000187:drug effects*; D015035:Zinc Oxide-Eugenol Cement / Q000633:toxicity*
chemical_list: D001453:Balsams; D015035:Zinc Oxide-Eugenol Cement; D006171:Gutta-Percha