title: [Analogs of natural nucleosides and their 5'-triphosphates carrying the amino group in 3'-position--highly effective inhibitors of replication, repair and transcription].
abstract: The new type of DNA and RNA synthesis inhibitors is found. These compounds are active in synthesis, catalyzed by bacterial DNA and RNA polymerases and by eukaryotic DNA polymerases in vitro and in DNA replication in vivo.
authors.forename: A A
authors.initials: AA
authors.lastname: Kraevskiĭ
authors.forename: S V
authors.initials: SV
authors.lastname: Kochetkova
authors.forename: A V
authors.initials: AV
authors.lastname: Azhaev
mesh_terms: D000606:Amino Sugars / Q000494:pharmacology*; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D004247:DNA / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D004260:DNA Repair / Q000187:drug effects*; D004261:DNA Replication / Q000187:drug effects*; D066298:In Vitro Techniques; D009705:Nucleosides / Q000494:pharmacology*; D009711:Nucleotides / Q000494:pharmacology*; D012313:RNA / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D012617:Sea Urchins; D014158:Transcription, Genetic / Q000187:drug effects*
chemical_list: D000606:Amino Sugars; D009705:Nucleosides; D009711:Nucleotides; D012313:RNA; D004247:DNA
vernacular_title: Analogi prirodnykh nukleozidov i ikh 5'-trifosfatov, nesushchie v 3'-polozhenii aminogruppu,--vysokoéffektivnye ingibitory replikatsii, reparatsii i transkriptsii.