title: [State of the antioxidant system in premature newborn infants during early postnatal period].
abstract: The main parameters of the antioxidant system--AOS (glutathione peroxidase, glutathione reductase, superoxide dismutase, ceruloplasmin, estriol, estradiol) were studied in 58 normal full-term infants and in 178 premature infants in the course of the early neonatal period. In the control group, the functioning of the AOS appeared more perfect and was characterized by phasic changes in the course of the first week of life. The premature infants demonstrated functional disorganization of both enzymatic (glutathione in particular) and hormonal components of the system of antiperoxide defence. This circumstance played a substantial part in the development of polysaturated fatty acids deficiency, which determined in turn the modification of the membrane lipid content and selective loss of cell sensitivity to neuro-humoral actions and unbalance in the system of cyclic nucleotides.
authors.forename: T K
authors.initials: TK
authors.lastname: Nabukhotnyĭ
authors.forename: V V
authors.initials: VV
authors.lastname: Pavliuk
authors.forename: V E
authors.initials: VE
authors.lastname: Markevich
authors.forename: T V
authors.initials: TV
authors.lastname: Chepurnaia
mesh_terms: D000367:Age Factors; D002570:Ceruloplasmin / Q000032:analysis; D004958:Estradiol / Q000097:blood; D004964:Estriol / Q000097:blood; D005979:Glutathione Peroxidase / Q000097:blood; D005980:Glutathione Reductase / Q000097:blood; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000097:blood / Q000378:metabolism*; D010088:Oxidoreductases / Q000097:blood*; D013482:Superoxide Dismutase / Q000097:blood
chemical_list: D004958:Estradiol; D010088:Oxidoreductases; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D002570:Ceruloplasmin; D005980:Glutathione Reductase; D004964:Estriol
vernacular_title: Sostoianie antioksidantnoĭ sistemy nedonoshennykh novorozhdennykh v rannem postnatal'nom periode.