Tissue-type plasminogen activator restriction fragment length polymorphism in the Chinese, Indians and Malays of Singapore.
A total of 215 subjects comprising 95 Chinese, 66 Malays and 54 Indians were investigated for restriction fragment length polymorphisms of the tissue-type plasminogen activator (PLAT) gene at an EcoRI site using the probe ptPA-4352. The phenotypic distribution showed a good agreement with the Hardy-Weinberg equilibrium. The gene frequencies of PLAT*1 were found to be 0.47 in the Chinese, 0.52 in the Malays and 0.41 in South Indians.
Saha
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Department of Paediatrics, Faculty of Medicine, National University of Singapore.
D044466:Asian People; D002681:China / Q000208:ethnology; D005787:Gene Frequency; D006801:Humans; D007194:India / Q000208:ethnology; D008296:Malaysia / Q000208:ethnology; D012150:Polymorphism, Restriction Fragment Length; D012846:Singapore; D010959:Tissue Plasminogen Activator / Q000235:genetics*
D010959:Tissue Plasminogen Activator