[Hypercalcemia in sarcoidosis].
In a 56-year-old man hypercalcaemia and kidney function impairment were the presenting symptoms of sarcoidosis. The diagnosis was supported by the finding of elevated 1,25-dihydroxyvitamin D levels and of a cluster of epithelioid macrophages in aspirated bone marrow. By exclusion of other granulomatous diseases and a favourable reaction of the hypercalcaemia and renal function to treatment with prednisone the diagnosis was confirmed. The relationship between the autonomous extrarenal production of 1,25-dihydroxyvitamin D and the hypercalcaemia is discussed.
Janssen
J A
JA
Pols
H A
HA
Baggen
M G
MG
Birkenhäger
J C
JC
D002117:Calcitriol / Q000097:blood; D003937:Diagnosis, Differential; D006801:Humans; D006934:Hypercalcemia / Q000097:blood / Q000209:etiology*; D007674:Kidney Diseases / Q000209:etiology / Q000652:urine; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D012507:Sarcoidosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D014376:Tuberculosis / Q000175:diagnosis
D002117:Calcitriol; D011241:Prednisone
Hypercalciëmie bij sarcoïdose.