title: Macromelanosomes in X-linked ocular albinism (XLOA).
abstract: A case of X-linked ocular albinism is reported. Characteristic Masson-Fontana positive and Dopa positive giant melanin granules were found in keratinocytes, melanocytes and upper dermis. Ultrastructurally the macromelanosome was composed of a dense core and a less dense surrounding mantle.
authors.forename: T
authors.initials: T
authors.lastname: Yoshiike
authors.forename: M
authors.initials: M
authors.lastname: Manabe
authors.forename: M
authors.initials: M
authors.lastname: Hayakawa
authors.forename: H
authors.initials: H
authors.lastname: Ogawa
mesh_terms: D000328:Adult; D000417:Albinism / Q000235:genetics* / Q000473:pathology; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D005127:Eye Color; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D008297:Male; D008543:Melanins / Q000378:metabolism; D008544:Melanocytes / Q000648:ultrastructure*; D008854:Microscopy, Electron; D012729:Sex Chromosome Aberrations / Q000235:genetics* / Q000473:pathology; D012867:Skin / Q000473:pathology; D014960:X Chromosome
chemical_list: D008543:Melanins