[Immunoenzyme determination of neurospecific antigen 10-40-4 in human and animal tissue and organ extracts].
IEA of brain specific antigen 10-40-4 in human and animal organs and tissues was elaborated. The method permits measuring the concentration of the antigen within the range from 1 to 120 ng/ml. The use of the method made it possible to confirm brain specificity of protein 10-40-4, since its brain content is 1500 to 2000 times higher than in other organs, and to estimate the percentage of cross-reaction between antigenic determinants of brain specific antigen 10-40-4 from different species of animals.
Kliushnik
T P
TP
Voloshchuk
S G
SG
Aksenova
M V
MV
Burbaeva
G Sh
GSh
D000818:Animals; D000941:Antigens / Q000032:analysis*; D001921:Brain / Q000276:immunology; D002143:Callitrichinae / Q000276:immunology; D002417:Cattle; D003429:Cross Reactions; D004285:Dogs; D000939:Epitopes / Q000032:analysis; D006168:Guinea Pigs; D006801:Humans; D007124:Immunoenzyme Techniques; D009419:Nerve Tissue Proteins / Q000032:analysis*; D009928:Organ Specificity; D011817:Rabbits; D051381:Rats; D013045:Species Specificity; D014020:Tissue Extracts / Q000276:immunology*
D000941:Antigens; D000939:Epitopes; D009419:Nerve Tissue Proteins; D014020:Tissue Extracts
Immunofermentnoe opredelenie neĭrospetsificheskogo antigena 10-40-4 v ékstraktakh tkaneĭ i organov cheloveka i zhivotnykh.