title: Campylobacter pylori and gastroduodenal ulcer disease. A prospective study in a Swedish population.
abstract: In a consecutive prospective series of 208 Swedish primary peptic ulcer patients, 146 gastric, 55 duodenal and 7 in both sites, gastroduodenitis was found in 97.6% of the cases. The mucosal inflammation was associated with CP in 87% and 91% of the gastric and duodenal ulcer cases respectively. No significant correlation was found between CP colonisation and the type or severity of mucosal inflammation. Gastric metaplasia was present in only 8% of 48 bulbar ulcer cases. Ulcer healing and eradication of CP was achieved in 52% of patients treated with bismuth subnitrate in combination with erythromycin or according to the triple approach.
authors.affiliation: Dept. of Clinical Pathology and Cytology, Falun Hospital, Sweden.
authors.forename: A
authors.initials: A
authors.lastname: Gad
authors.forename: M
authors.initials: M
authors.lastname: Hradsky
authors.forename: K
authors.initials: K
authors.lastname: Furugård
authors.forename: B
authors.initials: B
authors.lastname: Malmodin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000536:Aluminum Hydroxide / Q000627:therapeutic use; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D001729:Bismuth / Q000627:therapeutic use; D002169:Campylobacter Infections / Q000453:epidemiology*; D004338:Drug Combinations / Q000627:therapeutic use; D005260:Female; D006035:Glycyrrhiza; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D008276:Magnesium Hydroxide; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000188:drug therapy / Q000453:epidemiology* / Q000209:etiology; D010865:Pilot Projects; D010936:Plant Extracts / Q000627:therapeutic use; D011446:Prospective Studies; D017693:Sodium Bicarbonate; D013548:Sweden / Q000453:epidemiology
chemical_list: D000897:Anti-Ulcer Agents; D004338:Drug Combinations; D006635:Histamine H2 Antagonists; D010936:Plant Extracts; C002792:aluminum hydroxide, bismuth subnitrate, deglycyrrhizinised liquorice, magnesium carbonate, sodium bicarbonate drug combination; D000536:Aluminum Hydroxide; D017693:Sodium Bicarbonate; D008276:Magnesium Hydroxide; D001729:Bismuth