[In vivo protein synthesis from 14C-substrates in porcine tissues during the transition to postnatal development].
[2-14C] leucine, [1-14C] alanine, [1-14C] glucose, [1-14C] lactate and [1-14C] pyruvate utilization in the protein synthesis has been studied in vivo at early stages of postnatal development of piglets. It has been established, that during the first 24 hours after birth the protein synthesis intensity, judging by [2-14C] leucine incorporation, in liver, skeletal muscle, duodenal wall and subcutaneous tissue of piglets increases 5, 7, 6.5 and 2.1 times respectively. At the age of 1-2 h the radioactive carbon incorporation from [1-14C] glucose into the brain proteins is more pronounced than into the proteins of liver and skeletal muscle. During the first days of life the intensity of the label incorporation from [1-14C] glucose into liver and skeletal muscle proteins of piglets is enhanced, whereas in brain it remains at the same level. The degree of 14C carbon incorporation from [1-14C]-alanine, [1-14C] pyruvate and [1-14C] lactate into the liver and skeletal muscle proteins of 5-days-old piglets is approximately the same, 14C substrates of protein synthesis in brain and subcutaneous adipose tissue having some peculiarities.
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D000273:Adipose Tissue / Q000378:metabolism; D000375:Aging / Q000378:metabolism; D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D000831:Animals, Newborn; D001921:Brain / Q000378:metabolism; D050260:Carbohydrate Metabolism; D002250:Carbon Radioisotopes; D007413:Intestinal Mucosa / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D014176:Protein Biosynthesis; D013552:Swine / Q000254:growth & development*
D000596:Amino Acids; D002250:Carbon Radioisotopes
Sintez belkov in vivo iz 14C-substratov v tkaniakh svineĭ pri perekhode k postnatal'nomu razvitiiu.