The subjective assessment of cataract.
The medical treatment of cataract now appears to be a distinct possibility. A number of anti-cataract formulations are being clinically tested, and more clinical trials are being planned. To obtain a true assessment of a drug's efficacy, a battery of tests are needed which can accurately assess cataract progress. A clinical trial of the proposed anti-cataract drug Bendalina is being conducted. The six subjective methods used to assess cataract progression in the trial are presented. These are refractive error, LogMAR visual acuity, contrast sensitivity, glare sensitivity, retinal visual acuity and displacement threshold hyperacuity. The reasons for using each technique and their method of measurement is explained.
Elliott
D B
DB
University of Bradford Clinical Vision Research Unit, Optometry Department, University of Bradford, UK.
Gilchrist
J
J
Hurst
M
M
Pickwell
L D
LD
Sheridan
M
M
Weatherill
J
J
Whitaker
D
D
D000368:Aged; D002386:Cataract / Q000188:drug therapy / Q000503:physiopathology*; D015350:Contrast Sensitivity / Q000502:physiology; D006801:Humans; D007191:Indazoles / Q000627:therapeutic use; D008268:Macular Degeneration / Q000503:physiopathology; D012030:Refractive Errors / Q000503:physiopathology; D012542:Scattering, Radiation; D012684:Sensory Thresholds / Q000502:physiology; D014792:Visual Acuity
D007191:Indazoles; C036067:bendazac lysine