Cushing's disease. A cause of delayed growth and development.
An adolescent male with a typical cushingoid appearance presented to his physician with failure of linear growth and sexual development. Although his neuroradiologic workup was negative, his endocrinologic assessment pointed to the pituitary gland as the diseased organ. Selective transsphenoidal adenomectomy has thus far resulted in normalization of cortisol and growth hormone levels and furthered linear and sexual growth.
Geissinger
J D
JD
Zapata
C A
CA
Deeb
L C
LC
D000236:Adenoma / Q000175:diagnosis / Q000601:surgery; D000293:Adolescent; D000324:Adrenocorticotropic Hormone / Q000378:metabolism; D003480:Cushing Syndrome / Q000150:complications* / Q000503:physiopathology / Q000601:surgery; D002658:Developmental Disabilities / Q000209:etiology*; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008866:Microsurgery; D010911:Pituitary Neoplasms / Q000175:diagnosis / Q000601:surgery
D000324:Adrenocorticotropic Hormone