Chemical synthesis of picumast dihydrochloride.
The chemical synthesis of the antiallergic substance picumast dihydrochloride (3,4-dimethyl-7-[4-(4-chlorobenzyl)piperazine-1-yl]propoxycoumarin dihydrochloride) is described.
Witte
E C
EC
Department of Chemistry, Boehringer Mannheim GmbH, Fed. Rep. of Germany.
D055598:Chemical Phenomena; D002621:Chemistry; D003374:Coumarins / Q000138:chemical synthesis*; D006634:Histamine H1 Antagonists / Q000138:chemical synthesis*
D003374:Coumarins; D006634:Histamine H1 Antagonists; C013373:picumast