[Antiatherogenic properties of the soy protein isolate 500 E].
Two and 4 hours after a single intake of 50 g of protein isolate soy 500 E in the food, the activity of lysosomal hydrolases in blood platelets, the cholesterol (CS) content in lipoprotein-containing immune complexes, and the accumulation of CS in the subendothelial cells of human aorta intima reduced in introduction into a culture of serum obtained after intake of protein isolate soy. Direct introduction of a isolate 500 E water-alcohol extract into a culture of atherosclerotic plaques of human aorta intima caused decrease of the CS content in the cells and their proliferation. Protein isolate soy, therefore, produces an antiatherogenic effect in a cell culture and causes the antiatherosclerotic properties of serum.
Tutel'ian
V A
VA
Vasil'ev
A V
AV
Ren
L H
LH
D000328:Adult; D000936:Antigen-Antibody Complex / Q000032:analysis; D001161:Arteriosclerosis / Q000097:blood / Q000178:diet therapy* / Q000276:immunology / Q000473:pathology; D001792:Blood Platelets / Q000187:drug effects / Q000201:enzymology; D002478:Cells, Cultured; D004044:Dietary Proteins / Q000627:therapeutic use*; D004341:Drug Evaluation; D006801:Humans; D008055:Lipids / Q000097:blood; D008247:Lysosomes / Q000187:drug effects / Q000201:enzymology; D008297:Male; D008894:Milk Proteins / Q000627:therapeutic use; D014674:Plant Proteins, Dietary / Q000627:therapeutic use*; D030262:Soybean Proteins; D013025:Glycine max; D013997:Time Factors
D000936:Antigen-Antibody Complex; D004044:Dietary Proteins; D008055:Lipids; D008894:Milk Proteins; D014674:Plant Proteins, Dietary; D030262:Soybean Proteins
Antiaterogennye svoĭstva belkovogo izoliata soi 500 E.