Severe immune thrombocytopenia and the development of skin infarctions in a patient with an overlap syndrome.
A 49-year-old woman with clinical features of systemic lupus erythematosus, systemic sclerosis, Sjögren's and the antiphospholipid syndromes developed severe immune thrombocytopenia and skin infarctions. Both complications responded to immunosuppressive agents.
Dessein
P H
PH
Department of Medicine, University of the Witwatersrand Medical School, Johannesburg, South Africa.
Lamparelli
R D
RD
Phillips
S A
SA
Rubenchik
I A
IA
Zwi
S
S
D001323:Autoantibodies / Q000032:analysis; D003095:Collagen Diseases / Q000150:complications / Q000276:immunology*; D005260:Female; D006801:Humans; D007238:Infarction / Q000209:etiology* / Q000276:immunology; D008875:Middle Aged; D008947:Mixed Connective Tissue Disease / Q000150:complications / Q000276:immunology; D009220:Myositis / Q000150:complications / Q000276:immunology*; D010743:Phospholipids / Q000276:immunology; D012867:Skin / Q000098:blood supply*; D013577:Syndrome; D013921:Thrombocytopenia / Q000150:complications / Q000276:immunology*
D001323:Autoantibodies; D010743:Phospholipids