[Possible role of the molecular characteristics of sodium channel inactivation system of the nerve fiber in impulse coding].
A Hodgkin-Huxley type mathematical model of the Ranvier node aided to reveal interconnections between molecular characteristics of the sodium channels inactivation system (h-system) and impulse coding. Analysis of the second order properties of the system permitted to describe its energy profile, effective charge magnitudes and to suggest that in sensory fibres main part of the effective charge transfer occurs between the open and the first closed states whereas in motor fibres it occurs between the neighbouring closed states.
Gnetov
A V
AV
Krylov
B V
BV
D000818:Animals; D004553:Electric Conductivity; D006801:Humans; D007473:Ion Channels / Q000502:physiology*; D008433:Mathematics; D008564:Membrane Potentials; D008954:Models, Biological; D009412:Nerve Fibers / Q000502:physiology*; D011901:Ranvier's Nodes / Q000502:physiology; D012964:Sodium / Q000378:metabolism*; D013816:Thermodynamics
D007473:Ion Channels; D012964:Sodium
Vozmozhnaia rol' molekuliarnykh kharakteristik inaktivatsionnoĭ sistemy natrievykh kanalov nervnogo volkna v impul'snom kodirovanii.