title: Effect of fipexide on passive avoidance behaviour in rats.
abstract: The effect of fipexide, administered at different intervals after the learning trial of a single step-through type passive avoidance situation was studied. The administration of fipexide immediately after the learning trial resulted in a long-lasting facilitation of passive avoidance behaviour. On the contrary, the administration of this compound 1 h prior to the retention test failed to influence passive avoidance behaviour. The results suggest that fipexide facilitates memory consolidation but does not influence retrieval processes.
authors.affiliation: Department of Neurosciences, University of Cagliari, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Serra
authors.forename: M
authors.initials: M
authors.lastname: Collu
authors.forename: M C
authors.initials: MC
authors.lastname: Martellotta
authors.forename: A
authors.initials: A
authors.lastname: Forgione
authors.forename: W
authors.initials: W
authors.lastname: Fratta
mesh_terms: D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects*; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D010879:Piperazines / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D010879:Piperazines; C038628:fipexide