The influence of acute phenytoin administration on biotransformation and lipid peroxidation in the liver of rats of different ages.
Jahn
F
F
Institute of Pharmacology and Toxicology, Friedrich Schiller University, Jena, German Democratic Republic.
Kadiiska
M
M
Serbinova
E
E
Klinger
W
W
Stoytchev
T
T
D015660:7-Alkoxycoumarin O-Dealkylase / Q000378:metabolism; D000375:Aging / Q000378:metabolism; D000818:Animals; D001711:Biotransformation / Q000187:drug effects*; D019363:Cytochrome P-450 CYP1A1; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004790:Enzyme Induction / Q000187:drug effects; D005037:Ethylmorphine-N-Demethylase / Q000378:metabolism; D007527:Isoenzymes / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects*; D008099:Liver / Q000187:drug effects / Q000254:growth & development* / Q000378:metabolism; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism; D010088:Oxidoreductases / Q000378:metabolism; D010672:Phenytoin / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
D007527:Isoenzymes; D010672:Phenytoin; D003577:Cytochrome P-450 Enzyme System; D010088:Oxidoreductases; D015660:7-Alkoxycoumarin O-Dealkylase; D019363:Cytochrome P-450 CYP1A1; D005037:Ethylmorphine-N-Demethylase