title: Control of refractory supraventricular arrhythmias after unsuccessful closed-chest His bundle ablation.
abstract: Six patients underwent attempted catheter ablation of the His bundle for control of refractory supraventricular tachyarrhythmias. Permanent complete heart block was achieved in only three patients. All six patients have remained asymptomatic without antiarrhythmic medications over a follow-up period of six to 17 months (mean 10 months). There were no complications of the procedure apart from mild elevation of creatine kinase levels in three patients. In this series, resumption of atrioventricular (AV) conduction following attempted His bundle ablation was not associated with recurrence of symptomatic arrhythmias. Preservation of AV conduction may also obviate the need for permanent ventricular pacing.
authors.forename: J A
authors.initials: JA
authors.lastname: Johns
authors.forename: A J
authors.initials: AJ
authors.lastname: Black
authors.forename: R W
authors.initials: RW
authors.lastname: Harper
authors.forename: F
authors.initials: F
authors.lastname: Rosenfeldt
authors.forename: K
authors.initials: K
authors.lastname: Middlebrook
authors.forename: S T
authors.initials: ST
authors.lastname: Anderson
authors.forename: J
authors.initials: J
authors.lastname: Federman
authors.forename: A
authors.initials: A
authors.lastname: Pitt
mesh_terms: D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000503:physiopathology / Q000628:therapy*; D002036:Bundle of His / Q000503:physiopathology*; D006328:Cardiac Catheterization; D004562:Electrocardiography; D005260:Female; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013610:Tachycardia / Q000503:physiopathology / Q000628:therapy