title: Luteinizing hormone response to an oestradiol challenge in 5 intersex pigs possessing ovotestes.
abstract: After challenge with oestradiol benzoate, the mean maximum LH concentration in 5 XX intersex pigs possessing ovarian and testicular tissue, or only testicular tissue, was 2.10 (+/- 0.41) ng/ml compared with 8.9 ng/ml in mature domestic gilts. These results indicate that exposure of the pig brain to testosterone before Day 30 of gestation is important, or that early testicular secretions other than testosterone are involved in the determination of brain gender. The observation that some intersex pigs show normal oestrous cycles implies that the response to these prenatal factors is primarily quantitative rather than qualitative.
authors.affiliation: School of Agriculture, University of Edinburgh, UK.
authors.forename: C
authors.initials: C
authors.lastname: Chalmers
authors.forename: B
authors.initials: B
authors.lastname: Cook
authors.forename: G R
authors.initials: GR
authors.lastname: Foxcroft
authors.forename: R H
authors.initials: RH
authors.lastname: Hunter
mesh_terms: D000818:Animals; D012734:Disorders of Sex Development / Q000097:blood*; D004958:Estradiol / Q000097:blood / Q000494:pharmacology*; D005260:Female; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism*; D011374:Progesterone / Q000097:blood; D012733:Sex Differentiation; D012726:Sexual Behavior, Animal; D013552:Swine / Q000097:blood*
chemical_list: D011374:Progesterone; D004958:Estradiol; D007986:Luteinizing Hormone