title: [Incidence of intravenous thrombolytic therapy and fatalities in patients with acute transmural myocardial infarct (Q infarct). A study of observations from 1984 to 1987].
abstract: All patients admitted to the ICU with acute myocardial infarction (MI) were treated by the same protocol since 1984. We report the results in Q-wave-MI of 1987 compared to 1984. Age (67.2 +/- 12.4 vs. 66.8 +/- 11.4 years), sex distribution (70.1% vs. 71.9% male), time elapse between begin of symptoms and admittance to the hospital (15.5 +/- 27.0 vs. 15.0 +/- 32.5 hours) were similar in both years, but the total number of definite Q-MI decreased by 22% from 135 (1984) to 105 (1987). Inhospital mortality (20% vs. 23%) and ICU mortality (14% vs. 20%) tended to decrease, although differences did not reach statistical significance. This was paralleled by an increase in the rate of i.v. thrombolytic therapy from 17% (1984) to 28% (1987) of all patients with Q-MI. The percentage of patients who definitely received i.v. thrombolysis when all indication criteria were present and all contraindicatory factors excluded increased from 47% (1984) to 97% (1987). We conclude, that the performance of i.v. thrombolysis in all patients, who fulfill the general accepted criteria for thrombolysis may improve clinical course and outcome in a given population of patients with acute Q-wave-infarction.
authors.forename: B
authors.initials: B
authors.lastname: Alt
authors.forename: W
authors.initials: W
authors.lastname: Trost
authors.forename: H P
authors.initials: HP
authors.lastname: Schuster
authors.forename: B
authors.initials: B
authors.lastname: Ehlers
authors.forename: K F
authors.initials: KF
authors.lastname: Bodmann
authors.forename: F
authors.initials: F
authors.lastname: Köhler
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D001145:Arrhythmias, Cardiac / Q000628:therapy*; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008133:Long QT Syndrome / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000628:therapy*; D012008:Recurrence; D013300:Streptokinase / Q000008:administration & dosage*; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage*
chemical_list: D013300:Streptokinase; D014568:Urokinase-Type Plasminogen Activator
vernacular_title: Häufigkeit der intravenösen Thrombolysetherapie und Letalität bei Patienten mit akutem transmuralen Myokardinfarkt (Q-Infarkt). Eine Beobachtungsstudie von 1984 bis 1987.