title: Electrophysiologic basis of catheter ablation in atrial flutter.
abstract: A reentrant mechanism is believed to be responsible for atrial flutter. The recent development of the entrainment criteria further supports this theory, and there is a general consensus that circus movement is the underlying abnormality that supports this arrhythmia. In most clinical studies, abnormal fragmented (or double spike) electrograms, suggesting the presence of areas of localized slowing of conduction or block, have been reported. They are almost always recorded in the lower and posterior portion of the right interatrial septum, but also frequently in the high lateral portion of the right atrium. The determination of their involvement in the reentry pathway is important for designing curative procedures such as surgery or ablation. The low atrial septal area surrounding the mouth of the coronary sinus was suspected as being the critical area of slow conduction in atrial flutter. Rapid pacing at that site can yield a surface electrocardiographic pattern similar to the clinically occurring arrhythmias. Additionally, the flutter circuit can be accelerated during atrial pacing at fixed and slightly faster rates than the intrinsic tachycardia rate--the so-called entrainment phenomenon. When entrainment criteria are fulfilled, tachycardia termination being by definition ruled out, any concomitant recorded local type II block identifies an area that must be outside the circuit. Such local block may be recorded either spontaneously or during entrainment and therefore helps in identifying atrial slow conduction areas that do not belong to the reentrant path. This approach was applied to identify the optimal ablation site in 8 patients with long-standing drug resistant atrial flutter. In 7 of 8 patients, we were able to identify a fragmented potential in the low posteroseptal area during sustained atrial flutter.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Hôpital Cardiovasculaire et Pneumologique Louis Pradel, Lyon, France.
authors.forename: P
authors.initials: P
authors.lastname: Touboul
authors.forename: N
authors.initials: N
authors.lastname: Saoudi
authors.forename: G
authors.initials: G
authors.lastname: Atallah
authors.forename: G
authors.initials: G
authors.lastname: Kirkorian
mesh_terms: D001282:Atrial Flutter / Q000503:physiopathology / Q000601:surgery*; D001696:Biomechanical Phenomena; D006328:Cardiac Catheterization; D004564:Electrocoagulation; D004594:Electrophysiology; D006321:Heart / Q000503:physiopathology; D006325:Heart Atria; D006801:Humans; D009068:Movement