Hepatocellular lipofuscin in pre-eclampsia.
Thirty liver specimens from 30 pre-eclamptic women with and without liver dysfunction were examined for the amount of lipofuscin pigment deposited. The amount of hepatic lipofuscin correlated positively with plasma urate concentrations. This finding may indicate an involvement of oxygen-free radicals and xanthine oxidase in the pathophysiology of pre-eclampsia.
Minakami
H
H
Kimura
K
K
Tamada
T
T
Yasuda
Y
Y
Hirota
N
N
D005260:Female; D005609:Free Radicals; D006801:Humans; D008062:Lipofuscin / Q000032:analysis*; D008099:Liver / Q000032:analysis* / Q000166:cytology / Q000473:pathology; D010100:Oxygen / Q000378:metabolism*; D010860:Pigments, Biological / Q000032:analysis*; D011225:Pre-Eclampsia / Q000378:metabolism* / Q000503:physiopathology; D011247:Pregnancy; D014527:Uric Acid / Q000097:blood
D005609:Free Radicals; D008062:Lipofuscin; D010860:Pigments, Biological; D014527:Uric Acid; D010100:Oxygen