Preclinical evaluation of terbinafine in vivo.
The fungicidal activity of terbinafine which has been demonstrated in vitro for several strains of dermatophyte, filamentous and dimorphic fungi, has been demonstrated in vivo in model systems for dermatophytoses. This activity is accompanied by a fast onset of action which leads to superior antifungal efficacy when compared with fungistatic drugs.
Mieth
H
H
Petranyi
G
G
D000818:Animals; D000935:Antifungal Agents / Q000627:therapeutic use*; D003881:Dermatomycoses / Q000188:drug therapy*; D004195:Disease Models, Animal; D004341:Drug Evaluation; D006168:Guinea Pigs; D009281:Naphthalenes / Q000627:therapeutic use*; D000077291:Terbinafine
D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine