[Ultrastructural changes in thyrocytes exposed to the antithyroid preparations betazin and diiodotyrosine].
Ultrastructure changes in the thyroid gland cells of rats were studied when feeding of bethazine and diiodthyrozine to rats at doses 0.01, 0.1 and 1.0 mg/kg of body's weight for 12 months. The ultrastructure changes in thyrocytes typical both for hyper- and for hypofunction of the gland were revealed.
Trunov
V I
VI
Tarasenko
A P
AP
Pliuta
T V
TV
D000818:Animals; D013956:Antithyroid Agents / Q000494:pharmacology*; D004105:Diiodotyrosine / Q000031:analogs & derivatives* / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D008297:Male; D008854:Microscopy, Electron; D051381:Rats; D013961:Thyroid Gland / Q000187:drug effects* / Q000648:ultrastructure; D013997:Time Factors
D013956:Antithyroid Agents; D004105:Diiodotyrosine; C045165:betazine
Ul'trastrukturnye izmeneniia tirotsitov pri vozdeĭstvii antitireoidnykh preparatov--betazina i diĭodtirozina.