[In vivo migration of peritoneal macrophages, saturated with fats in vitro].
Our experiments aimed at the in vitro development of cells similar to macrophage foam cells of vessel wall. Fatty macrophages were produced by Intralipid incubation of peritoneal macrophages and their motility was studied in vivo. Our results showed that fat-saturated, isotope and colloid-gold marked macrophages can get through the vessel wall, so they are able to in vivo migration.
Pataki
M
M
Lusztig
G
G
D000818:Animals; D001161:Arteriosclerosis / Q000378:metabolism / Q000503:physiopathology; D002465:Cell Movement; D002478:Cells, Cultured; D002784:Cholesterol / Q000378:metabolism*; D005217:Fat Emulsions, Intravenous / Q000008:administration & dosage* / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D008077:Lipoproteins, LDL / Q000378:metabolism; D008264:Macrophages / Q000378:metabolism / Q000502:physiology*; D010537:Peritoneum; D010761:Phosphorus Radioisotopes; D051381:Rats; D011919:Rats, Inbred Strains
D005217:Fat Emulsions, Intravenous; D008077:Lipoproteins, LDL; D010761:Phosphorus Radioisotopes; D002784:Cholesterol
In vitro zsírral telített peritoneális macrophagok in vivo migrációja.