[Erythropoiesis inhibitor in the plasma of patients with hemopoietic dysplasias].
Altogether 21 patients were examined for an erythropoiesis inhibitor contained by the IgG fraction of the blood plasma. All these patients suffered from hemopoiesis depression. The inhibitor identified in the immunoglobulin fraction of the blood plasma of 40% of the patients manifested itself at the stage of erythroid precursors of bone marrow cells. The role of the humoral inhibitor in the development of erythropoietic disorders in these patients is under discussion.
Gudim
V I
VI
Korobkin
A V
AV
Turbina
N S
NS
Tsvetova
N V
NV
Ivanova
V S
VS
D000818:Animals; D001798:Blood Proteins / Q000032:analysis* / Q000494:pharmacology; D004920:Erythropoiesis / Q000187:drug effects; D004921:Erythropoietin / Q000097:blood; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D010198:Pancytopenia / Q000097:blood*; D011086:Polycythemia / Q000097:blood
D001798:Blood Proteins; D007074:Immunoglobulin G; C007627:erythropoiesis inhibiting factors; D004921:Erythropoietin
Ingibitor éritropoéza v plazme bol'nykh s gipoplaziiami krovetvoreniia.