[Neurotoxic action of muzolimine at high doses in uremic patients. Observation of a group of 29 subjects].
We report the results of a study on 29 patients affected by renal chronic insufficiency and treated with high doses of muzolimine. From our data it results that to the muzolimine is probable due a neurological syndrome very similar to combined sclerosis. Up today, it is not possible to know how and where the muzolimine develops its neurotoxic effect.
Gilli
M
M
Papurello
D
D
Chiadò Cutin
I
I
Bradac
G B
GB
Delsedime
M
M
Dettoni
E
E
Giangrandi
C
C
Fidelio
T
T
Rocci
E
E
Riccio
A
A
D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D009156:Muzolimine / Q000008:administration & dosage / Q000009:adverse effects*; D009422:Nervous System Diseases / Q000139:chemically induced*; D011720:Pyrazoles / Q000009:adverse effects*; D006435:Renal Dialysis; D014511:Uremia / Q000150:complications / Q000188:drug therapy* / Q000628:therapy
D011720:Pyrazoles; D009156:Muzolimine
Azione neurotossica della muzolimina ad alte dosi in pazienti uremici. Osservazione su un gruppo di 29 soggetti.