title: The effect of heat-stable extract from bovine sublingual salivary gland on serum cholesterol and triglyceride levels in normal and hypercholesterolemic rabbits.
abstract: An extract of bovine sublingual glands (SLF3) reduced the serum cholesterol levels of normal rabbits 34.6% and serum triglyceride levels 19.6% when injected intraperitoneally (i.p.) at 20 mg/kg body wt on alternate days for 7 days. SLF3 also reduced serum cholesterol levels 69.0% and triglyceride levels 46.5% in hypercholesterolemic rabbits, while in similar rabbits injected with a control muscle tissue extract, the rate of decrease in serum cholesterol levels was 33.3% and triglyceride levels 26.7%.
authors.affiliation: Department of Biochemistry, Istanbul Medical Faculty, University of Istanbul, Turkey.
authors.forename: H
authors.initials: H
authors.lastname: Omidfar
authors.forename: Y
authors.initials: Y
authors.lastname: Güven
authors.forename: H
authors.initials: H
authors.lastname: Oz
mesh_terms: D000818:Animals; D002417:Cattle; D002784:Cholesterol / Q000097:blood*; D002791:Cholesterol, Dietary; D006358:Hot Temperature; D006937:Hypercholesterolemia / Q000097:blood* / Q000209:etiology; D008297:Male; D011817:Rabbits; D013361:Sublingual Gland / Q000502:physiology*; D014020:Tissue Extracts / Q000494:pharmacology*; D014280:Triglycerides / Q000097:blood*
chemical_list: D002791:Cholesterol, Dietary; D014020:Tissue Extracts; D014280:Triglycerides; D002784:Cholesterol