title: New fluorinated carbocyclic nucleosides: synthesis and bioactivity.
abstract: Novel fluorinated carbocyclic nucleosides, (+-)-3'-deoxy-3'-fluoroaristeromycin and (+-)-2',3'-dideoxy-3'-fluoroaristeromycin have been synthesized. The antitumor activities of these compounds were studied.
authors.affiliation: Research Center, Asahi Grass Co., Ltd., Yokohama, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Nakayama
authors.forename: Y
authors.initials: Y
authors.lastname: Morizawa
authors.forename: Y
authors.initials: Y
authors.lastname: Matsumura
authors.forename: A
authors.initials: A
authors.lastname: Yasuda
authors.forename: K
authors.initials: K
authors.lastname: Uchida
mesh_terms: D000241:Adenosine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D007939:Leukemia L1210 / Q000188:drug therapy; D051379:Mice; D014407:Tumor Cells, Cultured
chemical_list: D000970:Antineoplastic Agents; C062349:2',3'-dideoxy-3'-fluoroaristeromycin; C062348:3'-deoxy-3'-fluoroaristeromycin; D000241:Adenosine