title: [Design and application of a computer program for comprehensive segregation analysis].
abstract: Based on the major locus genetic model, we designed a computer program used BASIC language for comprehensive segregation analysis in IBM microcomputer. The applicability of the program has been tested by analyzing 113 nuclear families with ichthyosis vulgaris selected by family method and family-history method, 98 nuclear families with ichthyosis vulgaris selected by family method as will as 101 nuclear families with sensorineural deafness of unknown causes. The program is useful for genetic analysis and genetic counselling.
authors.forename: Y
authors.initials: Y
authors.lastname: Hu
authors.forename: S Z
authors.initials: SZ
authors.lastname: Zhang
mesh_terms: D003198:Computer Simulation; D003638:Deafness / Q000235:genetics; D005190:Family; D006801:Humans; D007057:Ichthyosis / Q000235:genetics; D008838:Microcomputers; D008957:Models, Genetic; D012984:Software; D012985:Software Design