title: [Elephantiasis of the vulva and the legs. Medical and surgical treatment of a case of lymphatic filariasis].
abstract: After reviewing the main causes of elephantiasis in tropical countries, the results of combined medical and surgical treatment of a case of lymphatic filariasis are reported. Medical treatment consists of a cycle of high-dose mebendazole (40 mg/kg/die) and subsequent cycles of diethylcarbamazine at a habitual dose (6 mg/kg/die). In the interval, the elephantiasic right lip was removed surgically. The overall clinical results was good. Noteworthy was an unwanted, leukopenising side-effect of high-dose mebendazole.
authors.forename: A M
authors.initials: AM
authors.lastname: Huseen
authors.forename: E
authors.initials: E
authors.lastname: Tanganelli
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D004605:Elephantiasis, Filarial / Q000188:drug therapy / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D005260:Female; D005368:Filariasis / Q000628:therapy*; D006801:Humans; D007866:Leg; D008463:Mebendazole / Q000627:therapeutic use*; D014845:Vulvar Diseases / Q000188:drug therapy / Q000473:pathology / Q000601:surgery / Q000628:therapy*
chemical_list: D008463:Mebendazole
vernacular_title: Elefantiasi vulvare e degli arti inferiori. Terapia medica e chirurgica di un caso di filariosi linfatica.