title: Serum squamous cell carcinoma antigen levels in women with neoplasms of the lower genital tract and in healthy controls.
abstract: Squamous cell carcinoma antigen levels in 74 healthy volunteers, 57 patients with CIN and 91 patients with cervical carcinoma were determined by radioimmunoassay. 5.4% of healthy volunteers were above and all patients with CIN were below 3.0 ng/ml. 63.1% of 65 patients with primary squamous cell carcinoma, 1 out of 7 adenocarcinomas and 68.4% of 19 patients with recurrence of squamous cell carcinoma of the cervix had elevated SCC antigen levels. Elevated posttreatment levels carried a high risk factor of tumor persistence. Increases in SCC antigen levels during follow up usually signified recurrent carcinoma.
authors.affiliation: 2nd Department of Obstetrics and Gynecology, University of Vienna, Austria.
authors.forename: W
authors.initials: W
authors.lastname: Neunteufel
authors.forename: G
authors.initials: G
authors.lastname: Tatra
authors.forename: C
authors.initials: C
authors.lastname: Bieglmayer
mesh_terms: D000368:Aged; D000951:Antigens, Neoplasm; D002294:Carcinoma, Squamous Cell / Q000276:immunology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies; D002583:Uterine Cervical Neoplasms / Q000276:immunology*; D014625:Vaginal Neoplasms / Q000276:immunology*; D014846:Vulvar Neoplasms / Q000276:immunology*
chemical_list: D000951:Antigens, Neoplasm