title: [Prophylactic antibiotic therapy using oxacillin (Bristopen) in pediatric orthopedic surgery].
abstract: The aim of this study was to evaluate the efficiency of oxacillin in the prophylaxis of bone infections in orthopaedic surgery in children. Staphylococcus is the usual pathogen in orthopaedics. This is the reason of our choice: oxacillin. 420 patients are included: 195 control patients did not receive any prophylactic antibiotherapy; 225 patients received oxacillin. The oxacillin treatment started at anaesthetic induction and was carried on for 72 hours. In the control group, 7 superficial and 4 deep infections were observed, while a single superficial infection was noted in the oxacillin-treated group. This easy and inexpensive prophylactic treatment gave excellent results. We think that it should be systematically administered in orthopedic surgery to ensure as little complication as possible to the child.
authors.affiliation: Service Anesthésie, Hôpital Tenon-Trousseau, Paris.
authors.forename: J
authors.initials: J
authors.lastname: Bernière
authors.forename: S
authors.initials: S
authors.lastname: Schrayer
authors.forename: H
authors.initials: H
authors.lastname: Goldenberg
authors.forename: M
authors.initials: M
authors.lastname: Granados
authors.forename: L
authors.initials: L
authors.lastname: Boudet
authors.forename: M P
authors.initials: MP
authors.lastname: Scemama
authors.forename: A
authors.initials: A
authors.lastname: Lassaux
mesh_terms: D000293:Adolescent; D001424:Bacterial Infections / Q000517:prevention & control*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D009985:Orthopedics; D010068:Oxacillin / Q000627:therapeutic use*; D011292:Premedication
chemical_list: D010068:Oxacillin
vernacular_title: Antibiothérapie prophylactique par oxacilline (Bristopen) en chirurgie orthopédique infantile.