[Monitoring the effectiveness of amiodarone in the treatment of ventricular ectopic arrhythmias].
The authors included in their investigation a total of 18 patients (15 men and 3 women) with electric instability of the ventricular heart muscle during programmed stimulation of the ventricles. They administered amiodarone to the patients by the oral route, 200 or 400 mg per day for a period of 3 to 13 months. They compared the subjective symptomatology, the finding on monitoring of the ECG with the patient in bed or by means of Holter's system and the results of programmed stimulation of the ventricles before and after amiodarone administration. There was a marked decline in the frequency of subjective symptoms reported by the patients (above all syncopes disappeared completely) and there was a marked decline or complete disappearance of serious ventricular ectopic dysrhythmias. Amiodarone eliminated electric instability of the ventricles as proved by programmed stimulation of the ventricles completely in 39% and partly in 11% of the subjects.
Pleskot
M
M
Pidrman
V
V
Tilser
P
P
D000328:Adult; D000368:Aged; D000638:Amiodarone / Q000097:blood / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000188:drug therapy* / Q000503:physiopathology; D002304:Cardiac Pacing, Artificial; D004562:Electrocardiography / Q000187:drug effects; D005260:Female; D006352:Heart Ventricles; D006801:Humans; D008297:Male; D008875:Middle Aged; D013318:Stroke Volume / Q000187:drug effects
D000638:Amiodarone
Kontrola úcinnosti amiodaronu pri lécbĕ komorových ektopických arytmií.