Crystallization and preliminary crystallographic data for bovine antithrombin III.
Crystals of bovine antithrombin III were obtained in the presence of metal ions with ammonium sulphate as precipitating agent. Crystals belong to space group P4(1)2(1)2 or P4(3)2(1)2 with cell parameters a = b = 91.4 A, c = 383.1 A; there are two molecules per asymmetric unit. Electrophoresis experiments and amino acid sequence analysis of the N-terminal part of redissolved crystals suggest that the protein molecules are cleaved at the active site.
Samama
J P
JP
Laboratoire de Cristallographie Biologique, I.B.M.C. du C.N.R.S., Strasbourg, France.
Delarue
M
M
Mourey
L
L
Choay
J
J
Moras
D
D
D000818:Animals; D000990:Antithrombin III / Q000648:ultrastructure*; D002417:Cattle; D003461:Crystallography; D011487:Protein Conformation; D014961:X-Ray Diffraction
D000990:Antithrombin III