title: Effects of ingestion of thermally oxidized edible oils on plasma lipids, lipoproteins and postheparin lipolytic activity of rats.
abstract: Acute (after 4 hr) and short-term (after 7 days) effects of ingesting heated and unheated groundnut, coconut and safflower oils on plasma lipids, lipoproteins and postheparin lipopolytic activity (PHLA) were studied in rats. All heated oils were characterized by increases in carbonyl value, peroxide value and free fatty acid (FFA) content, except heated coconut oil which showed a decrease in FFA content. Heating procedure also did not alter to an appreciable extent their fatty acid compositions. Acute and short-term effects of feeding heated and unheated oils showed no significant differences in rat plasma levels of total cholesterol (TC), total triglycerides, total phospholipids, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol + very-low-density lipoprotein cholesterol, TC/HDL-C ratio and PHLA. Inspite of certain changes in some of the indices of thermal alteration of these heated oils, consumption of such heated oils by rats did not have any significant effect on various plasma parameters in these animals.
authors.forename: S M
authors.initials: SM
authors.lastname: Jethmalani
authors.forename: G
authors.initials: G
authors.lastname: Viswanathan
authors.forename: C
authors.initials: C
authors.lastname: Bandyopadhyay
authors.forename: J M
authors.initials: JM
authors.lastname: Noronha
mesh_terms: D000818:Animals; D004041:Dietary Fats / Q000494:pharmacology*; D006358:Hot Temperature / Q000009:adverse effects; D008055:Lipids / Q000097:blood*; D008066:Lipolysis / Q000187:drug effects*; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains / Q000378:metabolism*
chemical_list: D004041:Dietary Fats; D008055:Lipids; D008074:Lipoproteins