[Isolation and characteristics of cloned variants of influenza virus A/USSR/13/81 (H1N1-N3)].
Cloning in chick embryos and MDCK cell culture of influenza A/USSR/13/81 (H1N1-N3) virus isolated during virological examinations of autopsy materials from a child who had died from acute respiratory virus infection yielded three subpopulations of clones differing in antigenic, biological, physico-chemical properties and glycoprotein structures. One subpopulation contained hemagglutinin (HA) similar to that of the A/PR/8/34 strain and neuraminidase (NA) N3, the other HA similar to that of A/WS/33 and NA N1, and the third HA of the isolate proper and NA of the both serosubtypes mentioned.
Fursova
L M
LM
Chuvakova
Z K
ZK
Isaeva
E S
ES
D006385:Hemagglutination Inhibition Tests; D006389:Hemagglutinins, Viral / Q000032:analysis; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D009980:Influenza A virus / Q000145:classification / Q000276:immunology / Q000302:isolation & purification*; D009439:Neuraminidase / Q000276:immunology; D010948:Viral Plaque Assay; D014776:Virus Cultivation
D006389:Hemagglutinins, Viral; D009439:Neuraminidase
Poluchenie i kharakteristika klonirovannykh variantov virusa grippa A/SSSR/13/81 (H1N1-N3).