[The differentiation of Bordetella (B.) bronchiseptica strains. 8. The protective behavior of B. bronchiseptica strains in mice in relation to the loss of K factors].
K factors are phase-dependent, instable antigen components of B. bronchiseptica. Loss of K factors was induced by passaging on 10% horse blood agar. All K factors were not simultaneously eliminated. Cultures obtained from various passages were checked on white mice by Lienotox testing and in protectivity experiments. Culturing of B. bronchiseptica on 10% horse blood agar in Phase I probably had an adverse impact on expression of virulence-dependent factors. K factor expression in B. bronchiseptica was found to depend on both phase condition and culturing medium.
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D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology*; D000954:Antigens, Surface / Q000276:immunology*; D001884:Bordetella / Q000276:immunology*; D001885:Bordetella Infections / Q000276:immunology / Q000662:veterinary*; D005260:Female; D006168:Guinea Pigs; D008297:Male; D051379:Mice; D013552:Swine; D013553:Swine Diseases / Q000276:immunology*; D013556:Swine, Miniature
D000942:Antigens, Bacterial; D000954:Antigens, Surface; C030659:K antigens
Untersuchungen zur Differenzierung von Bordetella-(B.-)bronchiseptica-Stämmen. 8. Mitteilung: Untersuchungen zum protektiven Verhalten von B.-bronchiseptica-Stämmen bei Mäusen in Beziehung zum Verlust der K-Faktoren.