title: [In vitro susceptibility of dermatophyte strains to imidazole derivatives].
abstract: Recently, imidazole derivatives are being successfully used for the dermatomycoses. These drugs have the strongest antimycotic activity. 44 dermatophyte strains were isolated from our out-patient with dermatomycosis. Imidazole derivatives such as isoconazole, oxiconazole, bifonazole and tioconazole were studied their efficacy on these fungal agents in vitro. 4 imidazole derivatives were effective on all of the dermatophyte strains in less than or equal to 5 micrograms/ml concentration. Whereas, there were differences in Minimal Inhibition Concentration (MIC) and MIC50 values.
authors.affiliation: Gazi Universitesi, Tip Fakültesi, Dermatoloji Anabilim Dali, Oğretim Uyesi.
authors.forename: M
authors.initials: M
authors.lastname: Bozkurt
authors.forename: S
authors.initials: S
authors.lastname: Kuştimur
authors.forename: M A
authors.initials: MA
authors.lastname: Gürer
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology; D003883:Arthrodermataceae / Q000187:drug effects*; D003881:Dermatomycoses / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D007093:Imidazoles / Q000494:pharmacology* / Q000627:therapeutic use; D008825:Miconazole / Q000031:analogs & derivatives / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D007093:Imidazoles; D008825:Miconazole; C022155:oxiconazole; C020382:isoconazole; C036596:bifonazole; C020527:tioconazole
vernacular_title: Dermatofit suşlarinin imidazol türevlerine karşi invitro duyarliliği.