title: [Prognostic factors in operable non-small cell cancer of the lungs].
abstract: The influence of different factors on prognosis after radical operations in 316 patients with non-small cell peripheral pulmonary cancer was studied. In N0, the 3-year survival of the patients was 51.2%, 5-year--34.7%. In N1, the 3-year survival was 23.9%, in squamous cell cancer--40.6%, glandular--10.2%, 5-year survival--12.3%. The reduction of survival in N2 is significant in glandular, and in squamous cell cancer as well. In N2, the 3-year survival was 4.8%, 5-year survival was absent. It should be considered that in patients with stage T3N2 peripheral pulmonary cancer, there are subclinical metastases. The operation in this case is not a method for radical treatment. The influence of a tumor size on the prognosis is manifested in T3. Histologic structure in non-small cell cancer influences prognosis only at the stage T2N1 (in glandular cancer, the survival is significantly worse). The degree of differentiation in squamous cell cancer influences the prognosis. Tumor spreading to the adjacent structures makes prognosis worse, but the surgical treatment in such a case is justified.
authors.forename: V D
authors.initials: VD
authors.lastname: Zakharychev
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D011379:Prognosis; D013997:Time Factors
vernacular_title: Prognosticheskie faktory pri operabe'lnom nemelkokletochnom rake legkogo.