title: Indications for adaptation to differently high vitamin C supplies in guinea pigs. 1. Development of ascorbic acid levels after altered dosing.
abstract: Guinea pigs supplied with 5 mg/100 g vitamin in the food seem to be at the marginal substitution for a survival and show no ability to adapt the ascorbic acid metabolism to this low support. Guinea pigs longlastingly (6-8 weeks) supplied with 20 mg/100 g or 680 mg/100 g vitamin C in the food show the typical symptoms of an evolving adaptation by an overshooting in the course of the ascorbic acid levels in several organs after a switch to an extremely different vitamin C supply.
authors.affiliation: Biochemisches Institut der Universität Giessen.
authors.forename: E
authors.initials: E
authors.lastname: Degkwitz
authors.forename: R H
authors.initials: RH
authors.lastname: Bödeker
mesh_terms: D000311:Adrenal Glands / Q000378:metabolism*; D000818:Animals; D001205:Ascorbic Acid / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D006168:Guinea Pigs; D008099:Liver / Q000378:metabolism*; D013154:Spleen / Q000378:metabolism*
chemical_list: D001205:Ascorbic Acid