Isolation and characterization of an antimalarial agent of the neem tree Azadirachta indica.
The isolation and structure elucidation of gedunin [1], the antimalarial agent of Azadirachta indica, are reported. Its 1H- and 13C-nmr spectra were assigned by using one- and two-dimensional nmr spectroscopy, especially homonuclear and heteronuclear COSY, nOe difference, and COLOC experiments.
Khalid
S A
SA
Department of Pharmacognosy, Faculty of Pharmacy, University of Khartoum, Sudan.
Duddeck
H
H
Gonzalez-Sierra
M
M
D000962:Antimalarials / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010944:Plants / Q000032:analysis*
D000962:Antimalarials