A simple, one-step synthesis of N-acetyl-9-O-acetylneuraminic acid by enzymic transesterification mediated by porcine pancreas lipase in pyridine.
Forstner
M
M
Universitäts-Kinderklinik, Karl-Franzens-Universität Graz, Austria.
Freytag
K
K
Paschke
E
E
D000818:Animals; D004951:Esterification; D008049:Lipase / Q000378:metabolism*; D010179:Pancreas / Q000201:enzymology*; D011725:Pyridines; D012794:Sialic Acids / Q000138:chemical synthesis*; D013552:Swine
D011725:Pyridines; D012794:Sialic Acids; C025676:9-O-acetyl-N-acetylneuraminic acid; D008049:Lipase; C023666:pyridine