title: [Current trends in experimental peripheral nerve regeneration].
abstract: Large posttraumatic defects in the peripheral nervous system need to discover methods to solve the demand of nerve grafts. There is no definite answer now. The authors present a model for nervous regeneration studies. Experiments are performed in the Wistar rat. A venous isograft is used to bridge defects of various size in a divided rat sciatic nerve. The venous tube is a guide for axonal regeneration. In one series, the tube is filled with physiological saline and, in a second one, neonatal Schwann cells are injected in the venous isograft. Results recorded are a combination of quantitative methods: neurophysiology and morphometry. The injection of neonatal Schwann cells is able to stimulate nerve regeneration but not completely.
authors.forename: G
authors.initials: G
authors.lastname: Lejeune
authors.forename: M
authors.initials: M
authors.lastname: Foidart
authors.forename: A M
authors.initials: AM
authors.lastname: Severyns
authors.forename: P
authors.initials: P
authors.lastname: Delree
authors.forename: A
authors.initials: A
authors.lastname: Lejeune
authors.forename: D
authors.initials: D
authors.lastname: Clermont
authors.forename: G
authors.initials: G
authors.lastname: Rocoux
mesh_terms: D000818:Animals; D009416:Nerve Regeneration; D051381:Rats; D011919:Rats, Inbred Strains; D012583:Schwann Cells / Q000637:transplantation*; D012584:Sciatic Nerve / Q000502:physiology* / Q000601:surgery; D014680:Veins / Q000637:transplantation*
vernacular_title: Nouvelles orientations en régénération nerveuse périphérique expérimentale.