title: Lead concentrations in human bones from the Canadian population.
abstract: Stable lead was determined in post-mortem samples of human bones from three Canadian cities. All age groups and both sexes were represented. The cities selected for investigation were Winnipeg, Montreal and Charlottetown. No significant difference was found between the locations, although levels tended to be higher for Montreal. Mean lead concentrations (micrograms Pb/g ash) were 8.98 +/- 1.17, 11.11 +/- 1.74 and 8.47 +/- 1.06 for Winnipeg, Montreal and Charlottetown, respectively. Corresponding geometric means were 6.21, 7.88 and 6.71, respectively. Individual values ranged from 0.45 to 240.07 micrograms Pb/g ash. Concentrations were highest in the greater than 20-year age group, indicating increased body burden with age. An increase in lead concentration was observed for the ages 1-11 years with a decrease for the 12-19-year age group. Differences in concentrations between the sexes were not significant. Higher than average concentrations were observed in samples obtained from Winnipeg for the period 1976-1980, particularly in the 1-4-year age group. A similar pattern was observed in the air lead concentrations, suggesting a possible correlation between the concentrations of lead in the air and in bones at Winnipeg.
authors.affiliation: Health and Welfare Canada, Environmental Health Centre, Ottawa, Ontario.
authors.forename: E R
authors.initials: ER
authors.lastname: Samuels
authors.forename: J C
authors.initials: JC
authors.lastname: Meranger
authors.forename: B L
authors.initials: BL
authors.lastname: Tracy
authors.forename: K S
authors.initials: KS
authors.lastname: Subramanian
mesh_terms: D000367:Age Factors; D001822:Body Burden; D005260:Female; D006801:Humans; D007854:Lead / Q000032:analysis*; D008297:Male; D008350:Manitoba; D011325:Prince Edward Island; D011792:Quebec; D013131:Spine / Q000032:analysis*
chemical_list: D007854:Lead