Endodermal sinus tumor treated with high dose cisplatin.
A woman with an endodermal sinus tumor of the ovary stage IV obtained a short but complete remission after treatment with vinblastine, bleomycin and standard dose cisplatin. A second complete remission for 42+ months was obtained with a regimen of vinblastine, bleomycin, etoposide, and high dose cisplatin. This result suggests a dose-response relationship for cisplatin in ovarian germ cell tumors.
von Eyben
F E
FE
Department of Oncology, Tawan Hospital, Al Ain, Abu Dhabi, United Arab Emirates.
Siddiqui
M Z
MZ
Thunold
S
S
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D002945:Cisplatin / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008649:Mesonephroma / Q000188:drug therapy*; D010051:Ovarian Neoplasms / Q000188:drug therapy*
D002945:Cisplatin