[Secondary muscular carnitine deficiency following immunosuppressive treatment].
Carnitine deficiency syndromes can be classified into two groups: primary carnitine deficiency and secondary carnitine deficiency syndromes. A lipid storage myopathy with carnitine deficiency following an immunosuppressive therapy is described in a young man suffering from a possible polymyositis. After treatment with L-carnitine both biochemical and morphological features recovered. A secondary carnitine deficiency syndrome due to an immunosuppressive therapy is supposed.
Lössner
J
J
Klinik für Neurologie, Karl-Marx-Universität Leipzig.
Kühn
H J
HJ
Lehmann
J
J
Ziegan
J
J
D000328:Adult; D001379:Azathioprine / Q000008:administration & dosage / Q000009:adverse effects*; D002331:Carnitine / Q000172:deficiency*; D006801:Humans; D050356:Lipid Metabolism; D008297:Male; D009132:Muscles / Q000473:pathology; D009135:Muscular Diseases / Q000139:chemically induced* / Q000473:pathology; D009220:Myositis / Q000188:drug therapy* / Q000473:pathology
D001379:Azathioprine; D002331:Carnitine
Sekundärer muskulärer Carnitinmangel nach immunsuppressiver Behandlung.