title: [Biometric research in the diagnosis of precancerous states and endocervical cancer].
abstract: Smears of the endocervical channel taken from 58 patients with various endocervical conditions (reserve cell hyperplasia and dysplasia, reserve cell carcinoma in situ. Adenocarcinoma in situ, invasive glandular and poorly differentiated carcinoma) were stained by Feulgen method. Morphometrical (surface, perimeter, maximum and minimum diameter) and light microscopic (mean optical density of staining, its dispersion, DNA content) parameters of the epithelial cell nuclei were measured by means of telemetric image analyzer. The most informative biometrical indexes are found, the role of the DNA cytophotometry in the differential diagnosis is determined, the algorithm of the automated cytomorphological diagnosis of the dysplasia and endocervical carcinoma is developed.
authors.forename: V I
authors.initials: VI
authors.lastname: Novik
authors.forename: L S
authors.initials: LS
authors.lastname: Agroskin
authors.forename: G V
authors.initials: GV
authors.lastname: Papaian
authors.forename: L V
authors.initials: LV
authors.lastname: Solov'eva
mesh_terms: D000230:Adenocarcinoma / Q000032:analysis / Q000175:diagnosis / Q000648:ultrastructure; D000465:Algorithms; D001699:Biometry / Q000379:methods; D002278:Carcinoma in Situ / Q000032:analysis / Q000175:diagnosis / Q000648:ultrastructure; D002467:Cell Nucleus / Q000032:analysis / Q000648:ultrastructure; D002584:Cervix Uteri / Q000032:analysis / Q000648:ultrastructure; D003581:Cytodiagnosis; D004273:DNA, Neoplasm / Q000032:analysis; D003937:Diagnosis, Differential; D004848:Epithelium / Q000032:analysis / Q000648:ultrastructure; D005260:Female; D006801:Humans; D011230:Precancerous Conditions / Q000032:analysis / Q000175:diagnosis* / Q000648:ultrastructure; D002578:Uterine Cervical Dysplasia / Q000032:analysis / Q000175:diagnosis / Q000648:ultrastructure; D002583:Uterine Cervical Neoplasms / Q000032:analysis / Q000175:diagnosis* / Q000648:ultrastructure; D014626:Vaginal Smears
chemical_list: D004273:DNA, Neoplasm
vernacular_title: Biometricheskie issledovaniia v diagnostike predopukholevykh sostoianiĭ i éndotservikal'nogo raka.