[Characteristics of lymphoid subpopulations isolated from healthy subjects and those suffering from nonspecific ulcerative colitis].
Results of the studies of functional activity of lymphocyte subpopulations T+G, T-G, "O" subpopulations isolated peripheral blood of healthy persons and those with nonspecific ulcerative colitis (NUC) have been presented in this paper. The functional activity of the cells was assessed by means of local xenogeneic graft-vs-host reaction performed on CBA mice and by determination of nonspecific esterase enzyme. It has been established that analogous lymphocyte subpopulations influence the graft-vs-host reaction development in different ways depending on the condition of cell donor state: health/pathology. "O" subpopulations isolated from healthy persons hampered the graft-vs-host reaction development, and on the contrary stimulated it in patients with NUC. The assay of nonspecific esterase in lymphocytes showed that the least activity was noted in T+G and "O" cells in nonspecific ulcerative colitis.
Burmistrova
A L
AL
Ebert
L Ia
LIa
Teplova
S N
SN
D000818:Animals; D003093:Colitis, Ulcerative / Q000201:enzymology / Q000276:immunology*; D004950:Esterases / Q000097:blood; D006087:Graft vs Host Reaction / Q000276:immunology; D006801:Humans; D008214:Lymphocytes / Q000201:enzymology / Q000276:immunology*; D051379:Mice; D008808:Mice, Inbred CBA; D009000:Monocytes / Q000201:enzymology / Q000276:immunology / Q000637:transplantation; D010641:Phenotype; D012397:Rosette Formation; D014183:Transplantation, Heterologous
D004950:Esterases
Kharakteristika limfoidnykh subpopuliatsiĭ, vydelennykh ot zdorovykh lits i stradaiushchikh nespetsificheskim iazvennym kolitom.