The evaluation of a chemiluminescent assay for free thyroxine by comparison with equilibrium dialysis in clinical samples.
We have investigated the diagnostic performance of a chemiluminescence immunoassay for free thyroxine (Ciba Corning Magic Lite) in comparison with equilibrium dialysis. Agreement between the methods was satisfactory across a wide range of samples including those from patients with non-thyroidal illness. The results suggest that the chemiluminescence immunoassay is not subject to the artefacts of widely used analogue tracer methods for free thyroxine estimation.
Beaman
J
J
Department of Medical Biochemistry, University of Wales College of Medicine, Cardiff, UK.
Woodhead
J S
JS
Liewendahl
K
K
Mähönen
H
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003956:Dialysis; D005260:Female; D006801:Humans; D008163:Luminescent Measurements; D008297:Male; D008875:Middle Aged; D013960:Thyroid Function Tests; D013974:Thyroxine / Q000097:blood*
D013974:Thyroxine