[Ultrastructural changes in somatotropinocytes of the adenohypophysis during development of transplantation immunity].
The authors conducted two series of experiments on 144 mice of BAL/c and C57B1 line. It was established that in autotransplantation submicroscopical changes developing in somatotropinocytes are typical of stressor situation and reflect various phases of general adaptation syndrome. An increase in the number of cells in the phase of active proteinic synthesis and degranulation is observed in allotransplantation in inductive phase of immunogenesis. Before rejection the number of cells in the phase of active proteinic synthesis is decreased, and in degranulation phase--is increased.
Abdullakhodzhaeva
M S
MS
Umirov
I T
IT
D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D005790:General Adaptation Syndrome / Q000473:pathology* / Q000503:physiopathology; D006056:Golgi Apparatus / Q000648:ultrastructure; D013006:Growth Hormone / Q000378:metabolism; D051379:Mice; D008807:Mice, Inbred BALB C; D008928:Mitochondria / Q000648:ultrastructure; D010903:Pituitary Gland, Anterior / Q000648:ultrastructure*; D016038:Skin Transplantation; D013312:Stress, Physiological / Q000473:pathology*; D013997:Time Factors; D014181:Transplantation Immunology; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous
D013006:Growth Hormone
Ul'trastrukturnye izmeneniia v somatotropotsitakh adenogipofiza pri razvitii transplantatsionnogo immuniteta.