Effects of very low birth weight (VLBW) on visual development during the first year after term.
Behavioural visual functions were assessed in 155 very low birth weight (VLBW) infants during the first 12 months after expected term. Visual development was examined (mainly cross-sectionally) at 6 weeks, 3, 6, 9, and 12 months of corrected age by assessment of visual acuity, visual fields, optokinetic nystagmus and visual threat response. Many VLBW infants showed visual impairments (54.2%). No single visual function appeared to be specifically susceptible to impairments, deficits were often apparent across a range of functions. Visual impairments were observed at all test ages, and could already be assessed at 6 weeks of corrected age. The highest incidence of visual impairments was scored at 6 months corrected age. Beyond 6 months, less deficits were observed, suggesting in many infants a delayed rather than a permanently impaired visual development. In some infants deficits became evident at a later stage, after an apparently normal initial development. The results suggest that VLBW infants are at risk for impaired visual development.
van Hof-Van Duin
J
J
Department of Physiology I, Erasmus University Rotterdam, The Netherlands.
Evenhuis-van Leunen
A
A
Mohn
G
G
Baerts
W
W
Fetter
W P
WP
D006801:Humans; D007223:Infant; D007230:Infant, Low Birth Weight / Q000254:growth & development* / Q000502:physiology; D007231:Infant, Newborn; D009760:Nystagmus, Physiologic / Q000502:physiology*; D014786:Vision Disorders / Q000503:physiopathology*; D014792:Visual Acuity / Q000502:physiology*; D014794:Visual Fields / Q000502:physiology*