Tailoring a commercial radioimmunoassay to the range of levels of progesterone occurring in human serum during controlled ovarian hyperstimulation and following embryo/gamete transfer.
While the Pantex direct P radioimmunoassay is used widely in programs of assisted conception, its sensitivity and range do not encompass the wide range of levels of P in serum of many patients during COH and through the first trimester of pregnancy. The present communication details minor modifications to the proprietary Pantex assay which accommodate these requirements. The nature of the changes does not compromise the performance characteristics or simplicity of the original assay and facilitates precise, accurate, and rapid measurement of serum P between 0.05 and 1280 ng/ml.
Stone
B A
BA
Institute for Reproductive Research, Los Angeles, California 90017.
Quinn
K
K
Quinn
P
P
Vargyas
J M
JM
Marrs
R P
RP
D004624:Embryo Transfer; D005260:Female; D006801:Humans; D010062:Ovulation Induction / Q000379:methods; D011247:Pregnancy; D011374:Progesterone / Q000097:blood*; D011863:Radioimmunoassay / Q000379:methods*
D011374:Progesterone