title: Very low calorie diet induces opposite effects on sympathetic nervous system and adrenomedullary responses.
abstract: The effect of very low calorie diet (VLCD) on catecholamine excretion during 24 h was examined in nine obese men, with normal blood pressure, maintained on low sodium balance, after 3 days and 14 days of the diet period. A significant decrease in the total daily noradrenaline (NA) excretion was observed at the end of the diet (P less than 0.05). The daily excretion of adrenaline (A) increased (P less than 0.05) with a fall in the NA/A ratio (5.1 +/- 2.6 vs 12.5 +/- 3.7; P less than 0.03). The results demonstrate that the sympathetic nervous system is influenced to a greater extent by caloric intake than sodium homeostasis and that the VLCD exerts different effects on SNS and adrenomedullary secretion.
authors.affiliation: Dipartimento di Endocrinologia e Malattie Metaboliche, Policlinico Via del Pozzo 71, Modena, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Del Rio
authors.forename: P
authors.initials: P
authors.lastname: Marrama
authors.forename: P
authors.initials: P
authors.lastname: Fiorani
authors.forename: L
authors.initials: L
authors.lastname: Della Casa
mesh_terms: D000313:Adrenal Medulla / Q000378:metabolism*; D000328:Adult; D000704:Analysis of Variance; D004038:Diet, Reducing; D004039:Diet, Sodium-Restricted; D002149:Energy Intake; D004837:Epinephrine / Q000652:urine; D006801:Humans; D008297:Male; D009638:Norepinephrine / Q000652:urine; D009765:Obesity / Q000178:diet therapy* / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D013564:Sympathetic Nervous System / Q000378:metabolism*
chemical_list: D012964:Sodium; D009638:Norepinephrine; D004837:Epinephrine