[A comparative study of the efficacy of cryosurgical and operative treatments in transplanted tumors].
Antitumor efficacy of cryosurgery and standard surgical procedures for Lewis carcinoma, melanoma B16, Guerin's carcinoma and Walker's carcinosarcoma was compared in the treatment of 846 experimental animals. The study established the superiority or, at least, similar efficacy of cryosurgery in terms of cure, survival and radicality of primary tumor treatment. Unlike standard surgery, cryosurgery was followed by distant metastases being inhibited in mice. Although there was no significant difference in the incidence of metastases to regional lymph nodes in rats, it was higher than in untreated animals in both treatment groups. Cryonecrosis of tumor tissue is a factor of distant and regional metastases development following cryosurgery.
Mosienko
V S
VS
Kuz'menko
A P
AP
D000671:Amputation, Surgical; D000818:Animals; D002277:Carcinoma / Q000601:surgery; D002279:Carcinoma 256, Walker / Q000601:surgery; D003452:Cryosurgery; D005069:Evaluation Studies as Topic; D008175:Lung Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis; D008546:Melanoma, Experimental / Q000601:surgery; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000601:surgery*; D051381:Rats; D012074:Remission Induction; D013997:Time Factors
Sravnitel'noe izuchenie éffektivnosti kriokhirurgicheskogo i operativnogo lecheniia perevivnykh opukholeĭ.