[Infection of Chlamydia trachomatis and dysplasia lesions of the cervix uteri (CIN)].
With the aim of evaluating the correlation between dysplastic lesions of the uterine cervix associated or not with condylomatosis and Chlamydia T. infection, we carried out a serological study of anti-Chlamydia species-specific antibodies and a direct and/or a cultural investigation on a sample of 320 women who performed a Pap-test. The serological examination showed positivity (titer greater than or equal to 1:32) in 49 control subjects (with negative cytology) (23.7%); in 27 cases (43.5%) with actual diagnosis of condylomatosis/CIN associated or not with condylomatosis and in 28 cases (54.9%) with previous diagnosis of condylomatosis/CIN associated or not with condylomatosis. The cultural investigation did not show any significant difference among the groups above mentioned. Finally, the frequency of positive cases for anti-Chlamydia antibodies was estimated for each grade of actual or previous CIN: a greater frequency of positivity was noted in cases with CIN 3 (75%).
Alberico
S
S
Facca
M C
MC
Quaranta
M
M
Bogatti
P
P
Di Bonito
L
L
Dagaro
P L
PL
Dal Molin
G
G
Mandruzzato
G P
GP
D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis; D002278:Carcinoma in Situ / Q000150:complications*; D002690:Chlamydia Infections / Q000150:complications*; D002692:Chlamydia trachomatis / Q000276:immunology; D003218:Condylomata Acuminata / Q000150:complications*; D005260:Female; D006801:Humans; D002583:Uterine Cervical Neoplasms / Q000150:complications*
D000907:Antibodies, Bacterial
Infezione da Chlamydia Trachomatis e lesioni displastiche della cervice uterina (CIN).