New clinical aspects of Pearson's syndrome. Report of three cases.
We describe 3 patients affected by Pearson's syndrome, presenting anemia, exocrine pancreas failure, and skeletal abnormalities; insulin-dependent diabetes mellitus arose in two cases during the course of the disease. Bone marrow dysplasia and exocrine pancreas failure are also reported in Shwachman's syndrome; the two forms differ in bone marrow morphology. The clinical pattern of Pearson's syndrome can be so polymorphic as to increase the difficulties of differential diagnosis with Shwachman's syndrome.
Favareto
F
F
Caprino
D
D
Micalizzi
C
C
Rosanda
C
C
Boeri
E
E
Mori
P G
PG
D001853:Bone Marrow / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006402:Hematologic Diseases / Q000473:pathology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010182:Pancreatic Diseases / Q000473:pathology*; D013577:Syndrome