title: [Diffuse traumatic cerebral injuries in children].
abstract: A consecutive series of 41 patients aged less than 16 and admitted to the Department of Neurosurgery of the University of Milan in the period 1977-1978 following serious cranioencephalic trauma with Glasgow Coma Score (GCS) less than or equal to 7, duration of coma longer than 24 h and CT picture of diffuse lesion has been examined. These patients account for 5% of the paediatric cranial traumas observed in the same period and 66% of those in a state of coma. The CT picture made it possible to split patients into 3 groups: a) those without visible cerebral lesions and with subarachnoid and cisternal spaces present; b) those with small hyperdense lesions due to intraparenchymal or median/paramedian subcortical shearing lesions; c) those with marked constriction or absence of the 3rd ventricle and of the perimesencephalic cisterns. The first two pictures (a, b) were considered to be the expression of diffuse axonal damage, the last (c) of diffuse cerebral swelling. Intracranial pressure was monitored in about 50% of patients. The overall outcome of the series was favourable in more than 68% of cases with total mortality of 26.8%. Analysis of individual tomographic categories, however, showed that whereas the group of patients with diffuse axonal lesion presented nil mortality, those with diffuse cerebral swelling had 52% mortality owing to the onset of refractory intracranial hypertension.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.forename: E P
authors.initials: EP
authors.lastname: Sganzerla
authors.forename: R
authors.initials: R
authors.lastname: Massei
authors.forename: A
authors.initials: A
authors.lastname: De Santis
authors.forename: P
authors.initials: P
authors.lastname: Guerra
authors.forename: F
authors.initials: F
authors.lastname: Tiberio
authors.forename: A
authors.initials: A
authors.lastname: Parma
authors.forename: R
authors.initials: R
authors.lastname: Villani
authors.forename: R
authors.initials: R
authors.lastname: Trazzi
mesh_terms: D000293:Adolescent; D001930:Brain Injuries / Q000150:complications* / Q000000981:diagnostic imaging / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D003128:Coma / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011379:Prognosis; D014057:Tomography, X-Ray Computed
vernacular_title: Lesioni cerebrali traumatiche diffuse in età pediatrica.