[Effect of the endogenous peptide factor and vasopressin on the neurons of mollusks of different ages].
Electric reactions of the identified neurons in adult (10-12 months) and old (22-24 months) molluscs Lymnaea stagnalis to endogenous peptide isolated from the water soluble fraction of the Helix Pomatia brain homogenate as well as to vasopressin are studied. The endogenous peptide causes a significant activation of the burst both in adult and old neurons of the molluscs. No significant age-related differences in the pronouncement of the above shifts of the molluscan neurons are found. There is an increased sensitivity to the identified peptide, vasopressin, in the old individuals. A non-uniform change in the sensitivity of mollusk neurons to various neuropeptides may affect the synaptic conduction in old age.
Martynenko
O A
OA
Tott
S H
SH
D000200:Action Potentials / Q000187:drug effects / Q000502:physiology; D000367:Age Factors; D000818:Animals; D001921:Brain; D006372:Helix, Snails; D066298:In Vitro Techniques; D008195:Lymnaea / Q000187:drug effects / Q000502:physiology*; D008236:Lypressin / Q000494:pharmacology*; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D009479:Neuropeptides / Q000494:pharmacology*; D014020:Tissue Extracts / Q000494:pharmacology*
D009479:Neuropeptides; D014020:Tissue Extracts; D008236:Lypressin
Vliianie éndogennogo peptidnogo faktora i vazopressina na neĭrony prudovikov raznogo vozrasta.