[Properties of monoamine oxidase in the brain of mongolian gerbils during cerebral ischemia].
Properties of monoamine oxidase (MAO) were investigated in mongolian gerbils brain mitochondria isolated from cerebral cortex, striatum and hippocampus during cerebral ischemia. 5 min of ischemia caused inhibition of MAO activity (kynuramine as a substrate), alterations in substrate specificity and in kinetic curves form deflexion from hyperbolic type in all the brain structures investigated. Alterations in properties of MAO were observed in hippocampus already after I min of ischemia.
Goroshinskaia
I A
IA
Stoianovich
T
T
Michich
D V
DV
Mrshulia
B B
BB
D000818:Animals; D001921:Brain / Q000201:enzymology*; D002545:Brain Ischemia / Q000201:enzymology*; D003641:Deamination; D005849:Gerbillinae; D007700:Kinetics; D008995:Monoamine Oxidase / Q000378:metabolism*; D008996:Monoamine Oxidase Inhibitors / Q000378:metabolism; D013379:Substrate Specificity
D008996:Monoamine Oxidase Inhibitors; D008995:Monoamine Oxidase
Svoĭstva monoaminoksidazy v mozge mongol'skikh peschanok pri tserebral'noĭ ishemii.