[Demethylation and blood dosage of antidepressive imipramine drugs. Preliminary note].
The ability to demethylate the classical imipraminic antidepressants is a key factor for the immediate and long-term management of long cycles primary unipolar depressions. These are preliminary observations concerning two different cases of a well-demethylating patient, and a badly-demethylating one.
Pascalis
J G
JG
Clinique Universitaire de Psychiatrie, CHU-HRD, Reims, France.
Choisy
H
H
Havet
J M
JM
Lamiable
D
D
Schwartz
P
P
Théret
L
L
Wargny
E
E
D000328:Adult; D003866:Depressive Disorder / Q000097:blood / Q000188:drug therapy* / Q000378:metabolism; D005260:Female; D006801:Humans; D007099:Imipramine / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000627:therapeutic use
D007099:Imipramine
Déméthylation et dosage des antidépresseurs imipraminiques dans le sang. Note préliminaire.