Pyoderma gangrenosum in an allogeneic bone marrow transplant recipient.
We present the case of a 15-year-old boy who developed facial pyoderma gangrenosum following an allogeneic bone marrow transplantation for the treatment of a 'blast' crisis developing in the course of chronic myelogenous leukaemia. The lesion appeared 7 months before any evidence of relapse. The discussion is focused on both the presentation of pyoderma gangrenosum associated with myelo-proliferative disorders and its pathogenesis via the underlying immunosuppression.
Blanc
D
D
Schreiber
M
M
Racadot
E
E
Kahn
J Y
JY
Flesch
M
M
Viennet
G
G
Lab
M
M
Zultak
M
M
D000293:Adolescent; D016026:Bone Marrow Transplantation / Q000009:adverse effects; D005148:Facial Dermatoses / Q000473:pathology*; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000601:surgery; D008297:Male; D009336:Necrosis; D011711:Pyoderma / Q000473:pathology*; D013601:T-Lymphocytes / Q000473:pathology