[Preliminary results of comparative studies of cerebral hemiatrophy in humans and animals].
Fifteen cases of cerebral hemiatrophy were analyzed. In these patients, epilepsy and hemiparesis started in their early childhood with fatal outcome at ages of 4 through 74. In 10 cases intracranial inflammatory diseases or severe inflammations of the upper respiratory tract and middle ear preceded the neurological symptoms. In most patients the atrophic hemispheres were nonuniformly shrunk. The scale of morphological changes varied between moderately thinned convolutions and severely scarred shrunken cortical sites. In experimental studies in pigs, a temporary and unilateral impairment of the cerebrospinal fluid rinsing function and a gradual throtting of the small meningeal and cortical veins were induced by an artificial fibrosis which resulted in changes of the cortical tissues similar to those found in the patients.
Pollak
K G
KG
D000328:Adult; D000368:Aged; D000818:Animals; D001284:Atrophy; D002540:Cerebral Cortex / Q000473:pathology*; D002648:Child; D004195:Disease Models, Animal; D004827:Epilepsy / Q000209:etiology / Q000473:pathology* / Q000662:veterinary; D007839:Functional Laterality; D006429:Hemiplegia / Q000209:etiology / Q000473:pathology* / Q000662:veterinary; D006801:Humans; D008875:Middle Aged; D013552:Swine
Predvarite'lnye rezu'ltaty sravnite'lnogo issledovaniia gemiatrofii mozga u cheloveka i zhivotnykh.