Acute pancreatitis and reduction of H+ ion concentration in gastric secretions in experimental acute myocarditis produced by Indian red scorpion, Buthus tamulus, venom.
Crude venom (4 mg/kg) of scorpion (B. tamulus) was given in saline to anaesthetized dogs and rabbits. It produced a reduction in gastric H+ ion concentration in dogs with acute myocarditis. Simultaneously an increase in circulating amylase and lipase level was also observed. However 60% venom poisoned rabbits showed an elevated lipase level without a parallel increase in amylase. It is suggested that the venom acts directly on exocrine pancreas to cause acute pancreatitis.
Murthy
K R
KR
Medh
J D
JD
Dave
B N
BN
Vakil
Y E
YE
Billimoria
F R
FR
D000208:Acute Disease; D000818:Animals; D004285:Dogs; D005260:Female; D005750:Gastric Juice / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D008297:Male; D009205:Myocarditis / Q000139:chemically induced* / Q000150:complications; D010195:Pancreatitis / Q000139:chemically induced* / Q000150:complications; D011817:Rabbits; D012604:Scorpion Venoms / Q000633:toxicity*; D012605:Scorpions
D012604:Scorpion Venoms