title: Application of an analytical method to calcium acetylhomotaurinate determination in urine.
abstract: After urine purification, plasma and urine concentrations of calcium acetylhomotaurinate (Acamprosate, CaAOTA) were determined with a high-performance liquid chromatography method following i.v. administration of the drug in two dogs. Results obtained in serum were in good agreement with those found previously. The CaAOTA urine determination is a promising method to be used in healthy volunteers.
authors.affiliation: Laboratoire de Pharmacochimie, Unité d'Enseignement et de Recherche de Médecine Pharmacie de Rouen, Saint-Etienne-du-Rouvray, France.
authors.forename: C
authors.initials: C
authors.lastname: Chabenat
authors.forename: P
authors.initials: P
authors.lastname: Ladure
authors.forename: N
authors.initials: N
authors.lastname: Moore
authors.forename: P
authors.initials: P
authors.lastname: Boucly
authors.forename: F
authors.initials: F
authors.lastname: Boismare
mesh_terms: D000077443:Acamprosate; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D004285:Dogs; D005260:Female; D007275:Injections, Intravenous; D013056:Spectrophotometry, Ultraviolet; D013654:Taurine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000097:blood / Q000652:urine
chemical_list: D013654:Taurine; D000077443:Acamprosate