[Studies of physico-chemical properties and structure of aluminum hydrochloride obtained from aluminum isopropanolane].
Aluminium hydroxide gels were precipitated from aluminium isopropoxide by addition of water or aqueous solutions of Na2SO4, NaCl and NaNO3. The antacid activity of the gels was assessed on the basis of determinations of their total capacity to neutralize HCl, while structure of the gels was studied by X-ray diffraction analysis and IR spectrometry. It has been stated that prolonged storage, higher storage temperature and presence of water promote conversion of the active form of aluminium hydroxide gels in pharmaceutical preparations into less active forms.
Pawlaczyk
J
J
Maciałowicz
A
A
Kokot
Z
Z
D000433:1-Propanol / Q000032:analysis; D000535:Aluminum / Q000032:analysis; D000536:Aluminum Hydroxide / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology*; D003460:Crystallization; D004356:Drug Storage; D006358:Hot Temperature; D006851:Hydrochloric Acid / Q000037:antagonists & inhibitors*; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D013055:Spectrophotometry, Infrared; D014961:X-Ray Diffraction
D000536:Aluminum Hydroxide; D000433:1-Propanol; D000535:Aluminum; D006851:Hydrochloric Acid
Badanie właściwości fizykochemicznych i przemian fazowych zeli wodorotlenku glinowego otrzymanego z izopropanolanu glinu.