title: Electrical stimulation of the fastigial nucleus increases total cerebral blood flow in the monkey.
abstract: Internal and external carotid blood flows were monitored continuously in the barbiturate-anesthetized monkey with appropriately-sized electromagnetic flow probes. Electrical stimulation of the fastigial nucleus increased blood flow in both the internal and external carotid circulations in a frequency-dependent manner. This response was entirely intracerebral and independent of infra-bulbar mechanisms since it was present following high cervical spinal cord section. These data re-affirm the presence of the fastigial nucleus cerebral vasodilator response and add the observations that the response is present in the primate and markedly frequency-dependent.
authors.affiliation: Department of Neurology, Prince Henry Hospital, Sydney, Australia.
authors.forename: P J
authors.initials: PJ
authors.lastname: Goadsby
authors.forename: G A
authors.initials: GA
authors.lastname: Lambert
mesh_terms: D000818:Animals; D002529:Cerebellar Nuclei / Q000502:physiology*; D002560:Cerebrovascular Circulation; D004558:Electric Stimulation; D008251:Macaca / Q000502:physiology*; D008254:Macaca nemestrina / Q000502:physiology*; D014664:Vasodilation