Solid-phase synthesis of oligoribonucleotides.
An efficient method is described for solid-phase synthesis of oligoribonucleotides that involves use of the 9-fluorenylmethoxycarbonyl group (Fmoc) for 5'-protection, 4-methoxytetrahydropyran-4-yl (Mthp) for 2'-protection and a phosphoramidite coupling procedure.
Xu
Y Z
YZ
Medical Research Council, Laboratory of Molecular Biology, Cambridge, UK.
Lehmann
C
C
Slim
G
G
Christodoulou
C
C
Tan
Z K
ZK
Gait
M J
MJ
D004355:Drug Stability; D005898:Glass; D007202:Indicators and Reagents; D009843:Oligoribonucleotides / Q000138:chemical synthesis*
D007202:Indicators and Reagents; D009843:Oligoribonucleotides