title: Analysis of thought dissociation in schizophrenia on the basis of Wedensky-Pavlov phasic states.
abstract: Clinical analysis shows that a fundamental element of thought dissociation in schizophrenia is semantic and sound "derailments" of the associative processes. On a pathophysiological level these derailments could be explained through the parabiotic phasic states of Wedensky-Pavlov. In particular these derailments could be explained through the distortion of reciprocal relations between verbal structures by means of Pavlov's ultraparadoxical phase, wherein the positive stimuli become negative and vice versa. The author assumes that in appropriate (adequate) circumstances one of the mechanisms by which the leading idea directs the associative process is the reciprocal inhibiting-facilitating relations between the verbal (and nonverbal) structures. In schizophrenia (which Pavlov considered as a chronic hypnotic phasic state) these inhibiting-facilitating relations are disorganized and the associative process reveals phasic disintegrative deviations. Therefore thought dissociation in schizophrenia, by the magnifying glass of the pathology, indicates that a reciprocal inhibiting-facilitating relation is a basic principle of functional organization not only on the lower levels of the nervous system, but also on its highest levels.
authors.affiliation: Department of Psychiatry, Bulgarian Medical Academy, Sofia.
authors.forename: K
authors.initials: K
authors.lastname: Zaimov
mesh_terms: D001143:Arousal; D001245:Association Learning; D001288:Attention; D003214:Conditioning, Classical; D006801:Humans; D011939:Mental Recall; D012564:Schizophrenic Language; D012565:Schizophrenic Psychology; D013850:Thinking