Results of comparative determination of morphine in human hair using RIA and GC/MS.
Results of radioimmunological and mass-spectrometric tests for morphine in human hair samples, conducted independently in two separate laboratories, were compared. A large degree of qualitative and quantitative parity was observed for the two methods at morphine levels above 1000 micrograms/kg. Due to the variation of results at levels below 1000 micrograms/kg, more GC-MS tests are necessary as a safeguard. Additional GC/MS analyses of the same samples showed that discrepancies between the results of the two methods are not necessarily due to a variable response to the analyte. The results of the GC/MS examinations showed that it is also possible to distinguish between heroin and codeine addicts.
Sachs
H
H
Institute of Forensic Medicine, University of Ulm.
Arnold
W
W
D003061:Codeine / Q000032:analysis; D008401:Gas Chromatography-Mass Spectrometry; D006197:Hair / Q000032:analysis*; D003932:Heroin / Q000032:analysis; D006801:Humans; D009020:Morphine / Q000032:analysis*; D011863:Radioimmunoassay; D015813:Substance Abuse Detection / Q000379:methods*
D003932:Heroin; D009020:Morphine; D003061:Codeine