title: [Research on thixotropic parameters of whole blood from Chinese adult subjects].
abstract: This study measured the thixotropic parameters of whole blood from 314 healthy subjects (154 women, 160 men) with our modified method by Low Shear-30 Rheometer according to Huang's equation. We suggested the range of normal values of thixotropic parameters from man and woman group. The results demonstrated that no significant differences existed in the plasma viscosity (eta p) and fibrinogen between man and woman group. Man group had significantly higher values than those in woman group in hematocrit (HCT), yield stress (tau 0), Newtonian contribution of viscosity (mu), non-Newtonion contribution of viscosity (eta s-mu), apparent viscosity at 2.37s-1 (eta s), the equilibrium value of the structural parameter (A) and apparent kinetic rate constant of rouleaux breakdown (ARC). The man and woman groups could be separately divided into five subgroups on the basis of age. All parameters were compared with one another and treated statistically. We found that the levels of fibrinogen and eta p had an increasing trend with aging. In the old subgroup (greater than or equal to 60 years) of man and woman, HCT, tau 0, mu, eta s, (eta s-mu) and A had significantly lower values than those in young and middle age subgroups. However, it was very interesting that there were differences of ARC versus age between the man and woman groups, i.e., ARC in the man subgroup 3, 4 had lower values and in the woman subgroup 2, 3, 4 had higher values than their respective older subgroups did.
authors.forename: H Q
authors.initials: HQ
authors.lastname: Chen
authors.forename: G H
authors.initials: GH
authors.lastname: Zhong
authors.forename: L A
authors.initials: LA
authors.lastname: Li
authors.forename: X Y
authors.initials: XY
authors.lastname: Wang
authors.forename: Z Y
authors.initials: ZY
authors.lastname: Chen
authors.forename: D
authors.initials: D
authors.lastname: Zhou
authors.forename: Z N
authors.initials: ZN
authors.lastname: Xue
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001809:Blood Viscosity; D004903:Erythrocyte Aggregation; D005340:Fibrinogen / Q000032:analysis*; D006400:Hematocrit; D006801:Humans; D008875:Middle Aged; D012016:Reference Values; D012212:Rheology; D012737:Sex Factors
chemical_list: D005340:Fibrinogen