[Progressive systemic sclerosis, B-cell malignant lymphoma of the ileum and thyroid adenocarcinoma].
A patient with progressive systemic sclerosis with rapid evolution to death is presented. The post-morten examination revealed besides the typical changes of the progressive systemic sclerosis in the skin, kidneys, heart and blood vessels a B-cell ileal malignant lymphoma with generalized metastases, and an adenocarcinoma of the thyroid gland. A possible mechanism involved in the association of these diseases might be the action of the oncogenes modifying the cellular hormostasis and the immunological tolerance.
Rodrigues
C J
CJ
Bisi
H
H
Yoshinari
N
N
Marchiori
P E
PE
Cossermelli
W
W
D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology; D000328:Adult; D005260:Female; D006801:Humans; D007078:Ileal Neoplasms / Q000150:complications* / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000473:pathology; D012595:Scleroderma, Systemic / Q000150:complications* / Q000473:pathology; D013964:Thyroid Neoplasms / Q000150:complications* / Q000473:pathology
Esclerose sistêmica progressiva, linfoma maligno de células B em íleo e adenocarcinoma de tireóide.