Clear cell sarcoma of the kidney--a case report.
Clear cell sarcoma of the kidney (CCSK) is a highly malignant childhood tumor, distinguished from classic Wilms' tumor by its propensity to metastasize to the skeletal system. Authors described a case of CCSK from a 3-year-old boy in the right kidney, showing various histologic features, such as classic, epithelioid, trabecular, neurilemmoma-like, cystic and entrapped collecting tubular pattern. Ultrastructurally epithelial differentiation was absent. Immunohistochemically, none of the intrinsic tumor cells showed positive staining with the antibodies against the keratin, S-100 protein, carcinoembryonic antigen, vimentin, desmin and myoglobin, suggesting primitive mesenchymal cell in origin.
Seo
J S
JS
Department of Pathology, College of Medicine, Chung-Ang University, Seoul, Korea.
Park
Y W
YW
Song
K Y
KY
Chang
S T
ST
D002675:Child, Preschool; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000378:metabolism / Q000473:pathology*; D008297:Male; D009362:Neoplasm Metastasis; D012509:Sarcoma / Q000378:metabolism / Q000473:pathology*