[Complex assessment of the proliferation of epidermal and tumor cells in malignant skin lymphoma].
Keratinocyte and tumor cell proliferative activities in skin biopsy specimens of 49 patients with various forms of malignant lymphomas of the skin are analyzed. The mitotic index and 3H thymidine labeled nuclei index in the epidermal and tumor proliferate cells were under study; cytophotometry of the tumor cell DNA was carried out, as well as analysis of correlations of the examined parameters and the patients' life spans. The findings evidence an increase of the keratinocyte proliferative activity in epidermotropic malignant lymphomas of the skin, this pointing to the significance of epidermal abnormalities in the development of this condition.
Persina
I S
IS
Zabanova
E V
EV
Kotel'nikov
V M
VM
Kazantseva
I A
IA
Averbakh
E V
EV
D000328:Adult; D000368:Aged; D001345:Autoradiography; D001706:Biopsy; D002455:Cell Division; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D003592:Cytophotometry; D004273:DNA, Neoplasm / Q000032:analysis; D006801:Humans; D015603:Keratinocytes / Q000473:pathology*; D008223:Lymphoma / Q000473:pathology*; D008875:Middle Aged; D008938:Mitosis; D012878:Skin Neoplasms / Q000473:pathology*
D004273:DNA, Neoplasm
Kompleksnaia otsenka proliferatsiia épidermal'nykh i opukholevykh kletok pri zlokachestvennykh limfomakh kozhi.