title: Evaluation of metal implants coated with several types of ceramics as biomaterials.
abstract: The in vivo biocompatibility of metals coated with several different types of ceramics [alumina (alpha-Al2O3), titanium oxide (TiO2), titanium nitride (TiN), and hydroxyapatite (HAP)] was investigated. These composites had been devised for the purpose of incorporation into the stem of a total hip prosthesis. The materials were inserted into the mid-diaphyseal region of the femurs of adult dogs, and follow-up quantitative histological comparisons were performed for a period of up to 96 weeks. HAP-coated composites showed the best biocompatibility.
authors.affiliation: Department of Orthopaedic Surgery, Kyushu University, Fukuoka, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Hayashi
authors.forename: N
authors.initials: N
authors.lastname: Matsuguchi
authors.forename: K
authors.initials: K
authors.lastname: Uenoyama
authors.forename: T
authors.initials: T
authors.lastname: Kanemaru
authors.forename: Y
authors.initials: Y
authors.lastname: Sugioka
mesh_terms: D000537:Aluminum Oxide / Q000032:analysis / Q000494:pharmacology; D000818:Animals; D001672:Biocompatible Materials; D002516:Ceramics / Q000032:analysis / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D004285:Dogs; D006622:Hip Prosthesis; D006882:Hydroxyapatites / Q000032:analysis / Q000494:pharmacology; D008422:Materials Testing; D013193:Stainless Steel / Q000494:pharmacology; D014025:Titanium / Q000032:analysis / Q000494:pharmacology
chemical_list: D001672:Biocompatible Materials; D006882:Hydroxyapatites; D013193:Stainless Steel; D014025:Titanium; D000537:Aluminum Oxide