title: Reactive oxygen species production in circulating polymorphonuclear leukocytes in psoriasis.
abstract: Metabolic burst of polymorphonuclear leukocytes was evaluated by means of a luminol-enhanced chemiluminescence assay. Patients affected with active psoriasis showed a higher response than patients with chronic disease and controls when the neutrophils were stimulated with opsonized zymosan or phorbol myristate acetate.
authors.affiliation: Department of Dermatology, Catholic University, Rome, Italy.
authors.forename: C
authors.initials: C
authors.lastname: De Simone
authors.forename: P
authors.initials: P
authors.lastname: De Sole
authors.forename: G
authors.initials: G
authors.lastname: Di Mario
authors.forename: A
authors.initials: A
authors.lastname: Venier
authors.forename: D
authors.initials: D
authors.lastname: Cerimele
authors.forename: F
authors.initials: F
authors.lastname: Serri
mesh_terms: D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008163:Luminescent Measurements; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000378:metabolism* / Q000502:physiology; D011565:Psoriasis / Q000097:blood / Q000378:metabolism*; D013755:Tetradecanoylphorbol Acetate / Q000378:metabolism; D015054:Zymosan / Q000378:metabolism
chemical_list: D015054:Zymosan; D013755:Tetradecanoylphorbol Acetate