Effects of aging on mucociliary clearance.
Preliminary results from the relationship between aging and mucociliary clearance of inhaled 99-Tc human albumin particles (0.92-2.5 microns) are reported from two groups of healthy non-smokers: 1) 20-61-year-old (mean 42 years) and 2) 71-90-year-old (mean 79.5 years). The analytical procedure is presented, and on the basis of the analysis it is concluded that there is evidence for an age-related decline of the mucociliary clearance by a bi-phasic curve, similar to those reported in the literature for other physiological functions.
Incalzi
R A
RA
Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy.
Maini
C L
CL
Fuso
L
L
Giordano
A
A
Carbonin
P U
PU
Galli
G
G
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D005260:Female; D006801:Humans; D008168:Lung / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009079:Mucociliary Clearance / Q000502:physiology*