title: Anesthetic-related maternal mortality, 1954 to 1985.
abstract: This is a population-based study of the safety of obstetrical anesthesia in the Commonwealth of Massachusetts between 1954 and 1985. We used data collected by the state Committee on Maternal Mortality, which was founded in 1941. There were a total of 37 maternal deaths during the study period due to anesthetic-related complications. During the same time period, there were 886 maternal deaths. Thus, anesthetic-related mortality comprised 4.2% of all deaths, and the mortality rate was 1.5 per 100,000 live births between 1955 and 1964, 1.5 per 100,000 live births between 1965 and 1974, and 0.4 per 100,000 live births between 1975 and 1984. In the first decade of this study, aspiration during administration of a mask anesthetic was the primary cause of death. During the second decade, cardiovascular collapse associated with regional anesthesia was the primary cause of death. During the last decade of this study, all deaths were associated with general endotracheal anesthesia. As a result of this study and having identified the changes in the standard of care in Massachusetts that led to the reduction in maternal mortality, we offer recommendations to further improve the safety of anesthesia for childbirth in this country.
authors.affiliation: Harvard Medical School, Boston, MA.
authors.forename: B P
authors.initials: BP
authors.lastname: Sachs
authors.forename: N E
authors.initials: NE
authors.lastname: Oriol
authors.forename: G W
authors.initials: GW
authors.lastname: Ostheimer
authors.forename: J B
authors.initials: JB
authors.lastname: Weiss
authors.forename: S
authors.initials: S
authors.lastname: Driscoll
authors.forename: D
authors.initials: D
authors.lastname: Acker
authors.forename: D A
authors.initials: DA
authors.lastname: Brown
authors.forename: J F
authors.initials: JF
authors.lastname: Jewett
mesh_terms: D000293:Adolescent; D000328:Adult; D000765:Anesthesia, Conduction / Q000401:mortality; D000769:Anesthesia, Inhalation / Q000401:mortality; D000773:Anesthesia, Obstetrical / Q000401:mortality*; D000776:Anesthesiology / Q000193:education; D002423:Cause of Death; D005260:Female; D006323:Heart Arrest / Q000401:mortality; D006801:Humans; D008404:Massachusetts / Q000453:epidemiology; D008428:Maternal Mortality; D008991:Monitoring, Physiologic; D011015:Pneumonia, Aspiration / Q000401:mortality; D011247:Pregnancy