title: Proteinuria selectivity index in Saudi children with nephrotic syndrome.
abstract: Proteinuria selectivity index (PSI) was determined in 54 Saudi children with nephrotic syndrome whose renal biopsy showed minimal change in 13 and non-minimal histologic changes in 41 patients. The selectivity was determined with two pairs of proteins, IgG/transferrin and IgG/albumin. There was considerable overlap in the values of PSI in patients with minimal and non-minimal histological changes. The clinical utility of PSI in differentiating minimal change nephrotic syndrome and non-minimal change nephrotic syndrome is low.
authors.affiliation: Department of Paediatrics, King Khalid University Hospital, Riyadh, Saudi Arabia.
authors.forename: M B
authors.initials: MB
authors.lastname: Abdurrahman
authors.forename: O K
authors.initials: OK
authors.lastname: el Sheikh
authors.forename: A T
authors.initials: AT
authors.lastname: Elidrissy
authors.forename: W M
authors.initials: WM
authors.lastname: al Kahtani
authors.forename: A
authors.initials: A
authors.lastname: Lambourne
mesh_terms: D000918:Antibody Specificity; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007223:Infant; D007668:Kidney / Q000473:pathology; D009404:Nephrotic Syndrome / Q000150:complications / Q000473:pathology / Q000652:urine*; D011507:Proteinuria / Q000209:etiology*; D012529:Saudi Arabia
chemical_list: D007074:Immunoglobulin G