title: Lewis a blood group antigen of non-secretors: a receptor for candida blastospores.
abstract: This study tested the hypothesis that the Lewis a blood group antigen found predominantly on the cells of non-secretors might be one of the receptors for Candida species. Binding of strain 3118C to epithelial cells from either secretor or non-secretor donors was not inhibited by treating the cells with anti-Lewis a or anti-Lewis b antisera. Binding of strain 3091 to non-secretor cells was inhibited by pretreating the cells with anti-Lewis a, but this was not observed for secretor cells. The results suggest that Lewis a might be one of the receptors for some yeast strains.
authors.affiliation: Department of Bacteriology, Medical School, University of Edinburgh, U.K.
authors.forename: S J
authors.initials: SJ
authors.lastname: May
authors.forename: C C
authors.initials: CC
authors.lastname: Blackwell
authors.forename: D M
authors.initials: DM
authors.lastname: Weir
mesh_terms: D001665:Binding Sites; D002175:Candida / Q000276:immunology*; D002177:Candidiasis / Q000097:blood / Q000209:etiology / Q000276:immunology; D002448:Cell Adhesion / Q000276:immunology; D004848:Epithelium / Q000276:immunology / Q000382:microbiology; D006801:Humans; D066298:In Vitro Techniques; D007983:Lewis Blood Group Antigens / Q000276:immunology*; D009061:Mouth Mucosa / Q000276:immunology / Q000382:microbiology; D013171:Spores, Bacterial / Q000276:immunology
chemical_list: D007983:Lewis Blood Group Antigens