title: Bioactive polymers. LX. Kinetics of delayed release neomycin-xanthan complex.
abstract: The kinetics of delayed release neomycin-xanthan complex, and its antimicrobial activity, were studied. Delayed release neomycin (53.13% free neomycin) had zero-order release kinetics, when artificial tear solution was used as eluent. Microbiological tests revealed an activity of 380 units/mg, 10% higher than neomycin in its free form.
authors.affiliation: Polytechnic Institute of Jassy, Romania.
authors.forename: C
authors.initials: C
authors.lastname: Beldie
authors.forename: S
authors.initials: S
authors.lastname: Dumitriu
authors.forename: N
authors.initials: N
authors.lastname: Aelenei
authors.forename: M
authors.initials: M
authors.lastname: Popa
authors.forename: M I
authors.initials: MI
authors.lastname: Popa
authors.forename: D
authors.initials: D
authors.lastname: Dumitriu
mesh_terms: D003692:Delayed-Action Preparations; D066298:In Vitro Techniques; D009355:Neomycin / Q000493:pharmacokinetics*; D011135:Polysaccharides, Bacterial / Q000493:pharmacokinetics*; D019736:Prostheses and Implants
chemical_list: D003692:Delayed-Action Preparations; D011135:Polysaccharides, Bacterial; D009355:Neomycin; C002563:xanthan gum