[Hypoplasia of the intrahepatic bile ducts. A clinicopathologic study].
Paucity of intrahepatic bile ducts is considered part of the differential diagnosis of cholestatic syndromes in infancy. The purpose of this work is to inform the experience at the Hospital Infantil de Mexico Federico Gómez in the last few years on this entity. We reviewed the clinical charts as well as the biopsies of 31 patients with paucity of intrahepatic bile ducts. We find a slight male preponderance; the vast majority of patients were under three months of age. Cholestasis was the most frequent finding with significant clinicopathologic correlation. The remaining findings were similar to those previously reported, except for a peculiar distortion of the hepatic architecture which may be secondary to the hypoplastic development of the biliary tree. Finally, it is possible that the failure to thrive observed in this patient may commence in utero.
Valencia-Mayoral
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P
Calva-Rodríguez
R
R
Ahumada-Maldonado
H
H
D001653:Bile Ducts, Intrahepatic / Q000002:abnormalities* / Q000473:pathology / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D002779:Cholestasis / Q000151:congenital; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male
Hipoplasia de conductos biliares intrahepáticos. Estudio clinicopatológico.