Superoxide dismutase in the erythrocytes of acute alcoholics during detoxification.
The activity of erythrocyte superoxide dismutase in acute alcoholic patients on admission does not form a single population but clusters in two groups either above or below the normal range. The values in both groups revert towards the normal after a week of treatment. The divergent activities of this free radical scavenging enzyme between the two groups could not be explained by differences in age, haematology or liver function tests but are likely to be acute responses, possibly to diverse drinking patterns in the period immediately preceding admission.
Rooprai
H K
HK
Department of Neuropathology, Institute of Psychiatry, London, U.K.
Pratt
O E
OE
Shaw
G K
GK
Thomson
A D
AD
D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000201:enzymology* / Q000534:rehabilitation; D004912:Erythrocytes / Q000201:enzymology*; D005500:Follow-Up Studies; D005609:Free Radicals; D006801:Humans; D008108:Liver Diseases, Alcoholic / Q000201:enzymology; D008297:Male; D008875:Middle Aged; D013482:Superoxide Dismutase / Q000097:blood*
D005609:Free Radicals; D013482:Superoxide Dismutase