title: Anaesthesia for patients with mitochondrial myopathy.
abstract: The anaesthetic management for an infant with mitochondrial encephalomyopathy due to fumarase deficiency is described. Mitochondrial myopathies may produce skeletal and cardiac muscle abnormalities, central nervous system effects and metabolic problems. The solutions to the anaesthetic problems posed by these patients are discussed.
authors.affiliation: Shackelton Department of Anaesthetics, Southampton General Hospital.
authors.forename: A M
authors.initials: AM
authors.lastname: Burns
authors.forename: M P
authors.initials: MP
authors.lastname: Shelly
mesh_terms: D000768:Anesthesia, General; D001706:Biopsy; D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis; D005260:Female; D005649:Fumarate Hydratase / Q000172:deficiency*; D006801:Humans; D007223:Infant; D008099:Liver / Q000473:pathology; D008931:Mitochondria, Muscle / Q000648:ultrastructure*; D009132:Muscles / Q000473:pathology; D009135:Muscular Diseases / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D012867:Skin / Q000473:pathology
chemical_list: D005649:Fumarate Hydratase