title: An unusual case of bronchial carcinoid predominantly consisting of large cells.
abstract: A 58-year-old woman presented an unusual variant of bronchial carcinoid. A tumor measuring 20 x 25 mm was recognized upon gross examination in the upper lobe of the right lung. Microscopically, the tumor consisted of large polyhedral cells with a pseudoglandular arrangement similar to pheochromocytoma cells. Immunohistochemically, the tumor cells contained serotonin, S-100 protein and neuron-specific enolase. Thus, we consider this neoplasm to be a large cell variant of bronchial carcinoid which, to our knowledge, has not been described in the literature.
authors.affiliation: Department of Thoracic Surgery, Aichi Cancer Center Hospital, Nagoya.
authors.forename: M
authors.initials: M
authors.lastname: Shinoda
authors.forename: M
authors.initials: M
authors.lastname: Suyama
authors.forename: I
authors.initials: I
authors.lastname: Takagi
authors.forename: K
authors.initials: K
authors.lastname: Kunishima
authors.forename: S
authors.initials: S
authors.lastname: Nakamura
authors.forename: R
authors.initials: R
authors.lastname: Suzuki
authors.forename: S
authors.initials: S
authors.lastname: Hosoda
mesh_terms: D001984:Bronchial Neoplasms / Q000032:analysis / Q000473:pathology*; D002276:Carcinoid Tumor / Q000032:analysis / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D010751:Phosphopyruvate Hydratase / Q000032:analysis; D009418:S100 Proteins / Q000032:analysis; D012701:Serotonin / Q000032:analysis
chemical_list: D009418:S100 Proteins; D012701:Serotonin; D010751:Phosphopyruvate Hydratase