[HLA antigens on erythrocytes. II. A successful attempt to bind HLA serum antigens to erythrocytes].
In experiments in vitro it proved possible to bind HLA antigens in serum on erythrocytes after 4 to 48 hours incubation at 20 degrees C and 4 degrees C. With the period of incubation the amount of bound HLA antigens increased. The absorption and neutralization test revealed that the HLA antigen content of erythrocytes, thrombocytes and serum in a given subject is the same. HLA antigens present on the erythrocytes of some subjects were not removed from their surface even after nursing 15 times with saline. Based on the results of the experiment it is not possible to decide whether HLA antigens detected on red blood cells are an integral part of their membrane or whether they are bound to the red cells from plasma.
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D004910:Erythrocyte Membrane / Q000276:immunology*; D006680:HLA Antigens / Q000097:blood*; D006801:Humans
D006680:HLA Antigens
HLA antigeny na erytrocytech. II. Uspĕsný pokus o navázání HLA antigenů ze séra na erytrocyty.