Effects of verapamil, papaverine, sodium nitrite, and hydralazine on ethyl alcohol-induced contraction of the isolated human umbilical artery.
In this in vitro study, the vasodilator effects of certain drugs such as verapamil, papaverine, sodium nitrite and hydralazine on ethyl alcohol-induced contractions were investigated in the isolated human umbilical artery. Ethyl alcohol caused dose dependent contractions in this tissue. Papaverine, sodium nitrite and hydralazine were found to be effective.
Singirik
E
E
Calişkan
U
U
Cenik
A G
AG
Doğan
N
N
D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D006830:Hydralazine / Q000494:pharmacology; D009119:Muscle Contraction / Q000187:drug effects*; D009131:Muscle, Smooth, Vascular / Q000187:drug effects*; D010208:Papaverine / Q000494:pharmacology; D012977:Sodium Nitrite / Q000494:pharmacology; D014469:Umbilical Arteries / Q000187:drug effects*; D014700:Verapamil / Q000494:pharmacology
D006830:Hydralazine; D000431:Ethanol; D014700:Verapamil; D010208:Papaverine; D012977:Sodium Nitrite