title: Selective cleavage of N-terminal amino acid in a peptide by polymeric cobalt (III) triene complex.
abstract: Cellulose was functionalized to incorporate triethylenetetramine group. This was in turn converted into the polymeric analogue of cobalt(III)triene complex. The polymeric complex reacts with peptides resulting in the cleavage of amino end amino acid, thus suggesting the applicability of the polymeric reagent as a solid phase reagent for N-terminal determination.
authors.forename: A
authors.initials: A
authors.lastname: Mehra
authors.forename: S C
authors.initials: SC
authors.lastname: Gupta
authors.forename: C K
authors.initials: CK
authors.lastname: Narang
authors.forename: N K
authors.initials: NK
authors.lastname: Mathur
mesh_terms: D000596:Amino Acids / Q000032:analysis; D003035:Cobalt; D006868:Hydrolysis; D009942:Organometallic Compounds / Q000138:chemical synthesis*; D011108:Polymers / Q000138:chemical synthesis*; D011506:Proteins / Q000378:metabolism*
chemical_list: D000596:Amino Acids; D009942:Organometallic Compounds; D011108:Polymers; D011506:Proteins; D003035:Cobalt