Discriminant value of dyspeptic symptoms in peptic ulcer and non-ulcer dyspepsia.
The objective of the study was to determine whether discriminant analysis of characteristics of dyspepsia can differentiate peptic ulcer from non-ulcer dyspepsia in a Malaysian population. Two hundred and twenty six patients with dyspepsia were interviewed using a standard history questionnaire before undergoing upper gastrointestinal endoscopy. Forty seven patients had peptic ulcer while 149 others were classified as having non-ulcer dyspepsia. Stepwise logistic regression analysis was done on 25 variables. The study showed that only five of these variables could differentiate peptic ulcer from non-ulcer dyspepsia, namely, nocturnal pain, pain before meals or when hungry, absence of nausea, age and sex. A scoring system was devised based on these discriminant symptoms. At a sensitivity of 51%, the specificity for peptic ulcer was 83%, but only prospective studies will determine if this scoring system is of actual clinical value.
Kudva
M V
MV
Zawawi
M
M
Rafee
N
N
Ismail
O
O
Muda
J R
JR
D002940:Circadian Rhythm; D003937:Diagnosis, Differential; D016002:Discriminant Analysis; D004415:Dyspepsia / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008296:Malaysia; D008297:Male; D010146:Pain / Q000175:diagnosis; D010437:Peptic Ulcer / Q000175:diagnosis*; D011446:Prospective Studies; D012044:Regression Analysis