title: Profiles enriched in GABA-like immunoreactivity participate in serial synapses in the pontine nuclei of baboon (Papio anubis).
abstract: Using a postembedding immunogold procedure with an antiserum against glutaraldehyde-fixed GABA, we demonstrate GABA-like immunoreactivity in two classes of synaptic profiles in the pontine nuclei of baboon. One is an axon terminal in symmetrical synaptic contact with small or medium-sized GABA-immunonegative dendrites, the other is a pale, vesicle-containing profile resembling a dendrite or dendritic process which participates in serial synaptic arrangements. These synaptic arrangements, or triads, consist of a GABA-like immunoreactive, pale vesicle-containing profile being postsynaptic to a GABA-immunonegative axon terminal, and presynaptic to a small or medium-sized GABA-immunonegative dendrite. In at least some of these triads, the GABA-immunonegative axon terminals also contact the GABA-immunonegative dendrite directly.
authors.affiliation: Anatomical Institute, University of Oslo, Norway.
authors.forename: J E
authors.initials: JE
authors.lastname: Aas
authors.forename: O P
authors.initials: OP
authors.lastname: Ottersen
authors.forename: P
authors.initials: P
authors.lastname: Brodal
mesh_terms: D000818:Animals; D007150:Immunohistochemistry; D010215:Papio / Q000033:anatomy & histology / Q000378:metabolism*; D011149:Pons / Q000166:cytology / Q000378:metabolism*; D013569:Synapses / Q000378:metabolism* / Q000648:ultrastructure; D005680:gamma-Aminobutyric Acid / Q000378:metabolism* / Q000502:physiology
chemical_list: D005680:gamma-Aminobutyric Acid