title: [Cimetidine and ethanol].
abstract: Cimetidine inhibits hepatic drug metabolism, but its effect on ethanol elimination is less well established. The influence of cimetidine on the kinetics of ethanol is studied with three standardized drinking experiments. Cimetidine had no influence on the absorption or elimination of ethanol. There were significant differences in distribution of ethanol in consequence of inhibition of vascular histamine receptors after cimetidine application.
authors.affiliation: Inneren Abteilung, Medizinischen Akademie Carl Gustav Carus Dresden.
authors.forename: J
authors.initials: J
authors.lastname: Papke
authors.forename: H
authors.initials: H
authors.lastname: Borgmann
authors.forename: B
authors.initials: B
authors.lastname: Dökert
authors.forename: H
authors.initials: H
authors.lastname: Bartels
authors.forename: D
authors.initials: D
authors.lastname: Krause
mesh_terms: D000293:Adolescent; D000328:Adult; D002927:Cimetidine / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000493:pharmacokinetics*; D005260:Female; D006801:Humans; D007408:Intestinal Absorption / Q000187:drug effects; D008297:Male; D008657:Metabolic Clearance Rate
chemical_list: D000431:Ethanol; D002927:Cimetidine
vernacular_title: Cimetidin und Ethanol.