title: [Effect of carbohydrate components of ristomycin A on platelet aggregation in human plasma].
abstract: In the process of the investigation, conditions for specific removal of arabinose in tetrasaccharide of ristomycin A, a glycopeptide antibiotic as well as conditions for simultaneous removal of arabinose and mannose-2 bound to actinoidinic acid were determined. The role of arabinose in manifestation of the ristomycin A ability to induce platelet aggregation was shown to be important. Mannose-2 also had the same ability while its level was somewhat lower.
authors.forename: Zh P
authors.initials: ZhP
authors.lastname: Trifonova
authors.forename: N V
authors.initials: NV
authors.lastname: Sturman
authors.forename: A O
authors.initials: AO
authors.lastname: Zheltova
authors.forename: G S
authors.initials: GS
authors.lastname: Katrukha
mesh_terms: D001089:Arabinose / Q000032:analysis / Q000494:pharmacology*; D055598:Chemical Phenomena; D002621:Chemistry; D003029:Coagulants; D006801:Humans; D066298:In Vitro Techniques; D008358:Mannose / Q000032:analysis / Q000494:pharmacology*; D010974:Platelet Aggregation / Q000187:drug effects* / Q000502:physiology; D012310:Ristocetin / Q000032:analysis / Q000494:pharmacology*
chemical_list: D003029:Coagulants; D012310:Ristocetin; C016719:ristocetin A; D001089:Arabinose; D008358:Mannose
vernacular_title: Vliianie uglevodnogo sostava ristomitsina A na agregatsiiu trombotsitov plazmy krovi cheloveka.