[Treatment of intractable pneumonia in the elderly].
To study the problems of treatment which arise in intractable pneumonia in the elderly, randomly selected cases from recent cases of pneumonia aged over 65 (n = 657) in the Tokyo Metropolitan Geriatric hospital were annually retrospectively. Among factors which contributed to intractable pneumonia, malnutrition, aspiration, renal and cardiac failure as well as malignancy were considered statistically significant. The number of cases of the intractable pneumonia which were complicated with multiple organ failure (MOF) increased recently. Hypoxemia was one of the predisposing factor of pneumonia with MOF. It should be emphasized that well-designed supportive therapy as well as choice of appropriate antibiotics is important to determine the outcome of intractable pneumonia in the elderly. Problems concerning the pathogenesis of organizing pneumonia among intractable pneumonia cases which has recently increased in prevalence among the elderly was also discussed.
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D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D009102:Multiple Organ Failure / Q000150:complications; D011014:Pneumonia / Q000150:complications / Q000628:therapy*; D011897:Random Allocation; D012189:Retrospective Studies; D012307:Risk Factors
D000900:Anti-Bacterial Agents