[The toxicologic characteristics of a new SAKAP-based benzyl benzoate ointment].
The formula of a new stable 20% benzylbenzoate emulsion is presented, so are the results of studies on its toxicity, local irritating and sensitizing effects in guinea pigs. For comparison, the same characteristics of currently used 20% water-soap benzylbenzoate emulsion and of the new ointment base, SAKAP (acryl copolymer), have been examined. Both the ointment and its base have proved to be safe.
Sokolova
T V
TV
Alchangian
L V
LV
Alekseev
K V
KV
Aĭvazian
A A
AA
Stepanov
Iu V
IuV
D000179:Acrylates / Q000633:toxicity*; D000818:Animals; D001565:Benzoates / Q000633:toxicity*; D004355:Drug Stability; D004655:Emulsions; D006168:Guinea Pigs; D006863:Hydrogen-Ion Concentration; D007306:Insecticides / Q000633:toxicity*; D009824:Ointments; D011108:Polymers / Q000633:toxicity*; D011409:Propylene Glycols / Q000633:toxicity*; D012869:Skin Absorption / Q000187:drug effects; D012882:Skin Tests; D013997:Time Factors
D000179:Acrylates; D001565:Benzoates; D004655:Emulsions; D007306:Insecticides; D009824:Ointments; D011108:Polymers; D011409:Propylene Glycols; C044876:acrylic acid-allyl pentaerythritol copolymer; C006723:benzyl benzoate
Toksikologicheskaia kharakteristika novoĭ mazi benzilbenzoata na osnove SAKAP.