title: Isolated Castleman's disease in the neck.
abstract: It can be difficult for the clinician to diagnose Castleman's disease when cervical lymphadenopathy is its only manifestation. The diagnostic challenge may be compounded by the presence of a profound fibrotic reaction secondary to multiple biopsy attempts that are frequently required to establish a diagnosis. Castleman's disease is a benign lymphoproliferative disorder and it most frequently involves the mediastinal lymph nodes. The recognition of an occasional variant of this disorder with a potential malignant course and its association with AIDS calls for a greater awareness of this disease among all clinicians.
authors.forename: V K
authors.initials: VK
authors.lastname: Anand
authors.forename: J R
authors.initials: JR
authors.lastname: House
mesh_terms: D000328:Adult; D001706:Biopsy; D005871:Castleman Disease / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009333:Neck / Q000473:pathology*