Ochratoxin A and dietary protein. 1. Effects on body weight, feed conversion, relative organ weight, and mortality in three-week-old broilers.
An experiment with a completely randomized 3 x 4 factorial design was used to study the effects of ochratoxin A (0, 2, and 4 mg/kg) and protein (14, 18, 22, and 26%) in three-wk-old broilers. The diets were based on ground yellow corn and dehulled soybean meal. Four hundred and eighty Hubbard x Hubbard broilers were randomly placed in battery brooders, with 10 birds per pen. Each treatment was replicated four times. Body weight increased with rising levels of protein, and decreased with rising levels of ochratoxin A (OA). The efficiency of feed utilization was improved in broilers fed 22 and 26% protein, compared with broilers fed 14 and 18% protein. The efficiency of feed utilization was lower for the birds fed 4 mg/kg of OA, compared with broilers fed 0 and 2 mg/kg of OA, respectively. Using OA increased the relative weight of the liver, kidney, spleen, pancreas, proventriculus, gizzard, and heart and also significantly decreased the relative weight of the bursa of fabricius. A significant interaction between OA and protein was seen in terms of the relative weight of the liver, pancreas, and gizzard, indicating that the rising protein levels spared the OA effect on those organs. Mortality was highest among the broilers fed 4 mg/kg of OA. Protein regression coefficients (beta's) were positive with respect to 21-day body weight and were negative for the feed:gain ratio and mortality, suggesting that protein provided beneficial effects.
Gibson
R M
RM
Department of Poultry Science, Texas Agricultural Experiment Station, Texas A&M University System, College Station 77843.
Bailey
C A
CA
Kubena
L F
LF
Huff
W E
WE
Harvey
R B
RB
D000821:Animal Feed; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002645:Chickens / Q000254:growth & development* / Q000378:metabolism; D004044:Dietary Proteins / Q000378:metabolism*; D004435:Eating; D005506:Food Contamination; D008297:Male; D009793:Ochratoxins / Q000633:toxicity*; D009929:Organ Size / Q000187:drug effects; D011897:Random Allocation; D012044:Regression Analysis
D004044:Dietary Proteins; D009793:Ochratoxins; C025589:ochratoxin A