title: [Morphology of the gastric mucosa in burns and the pathogenetic aspects of its injuries].
abstract: The biopsies of the stomach fundus taken during the endoscopical examination of 80 patients with the thermal skin burns were studied histologically and electron microscopically. Acute erosions or ulcers localizing in the stomach fundus were observed. Various types of endocrine cells (ECL-, D-, P- and AL-cells) are identified in the main glands epithelium. The differences in the functional specialization of substances produced by these cells determine their pathogenetic role in the development of stomach acute erosions and ulcers in patients with the burn disease. The glandular cell desquamation in the stomach lumen is due to the weakening of the cell contacts and the basal membrane damage. Some cell organelles including the pepsinogen granules penetrate into the lamina propria of the mucous membrane. The conditions that develop in the mucous membrane may enhance its alteration without participation of mucous barrier.
authors.forename: S G
authors.initials: SG
authors.lastname: Khomerikin
authors.forename: G G
authors.initials: GG
authors.lastname: Donadze
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002056:Burns / Q000150:complications* / Q000473:pathology; D005336:Fiber Optic Technology; D005753:Gastric Mucosa / Q000473:pathology*; D005773:Gastroscopy; D006801:Humans; D008854:Microscopy, Electron; D008875:Middle Aged; D013276:Stomach Ulcer / Q000209:etiology* / Q000473:pathology; D013997:Time Factors
vernacular_title: Morfologiia slizistoĭ obolochki zheludka pri ozhogovoĭ bolezni, patogeneticheskie aspekty ee povrezhdeniĭ.