title: [Characteristics of osteosarcomas and morphological changes in the rat thymus during the combined action of gamma-radiation and 239Pu].
abstract: Under the combined effect of external gamma-irradiation and 239Pu, osteosarcomas occur more frequently and at earlier times, and have more pronounced multicentric pattern of growth and metastatic spreading than occurs with the two agents delivered separately. The difference is in the increased development of tumors and the decreased osteogenesis. Tumor carriers develop atrophy of thymus lymphoid tissue more frequently than normal ones.
authors.forename: Z M
authors.initials: ZM
authors.lastname: Bukhtoiarova
authors.forename: S S
authors.initials: SS
authors.lastname: Spirina
mesh_terms: D000818:Animals; D003037:Cobalt Radioisotopes; D005720:Gamma Rays; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000473:pathology*; D012516:Osteosarcoma / Q000209:etiology* / Q000473:pathology; D011005:Plutonium; D051381:Rats; D011919:Rats, Inbred Strains; D013950:Thymus Gland / Q000473:pathology*
chemical_list: D003037:Cobalt Radioisotopes; D011005:Plutonium
vernacular_title: Kharakteristika osteosarkom i morfologicheskikh izmeneniĭ timusa krys pri sovmestnom vozdeĭstvii gamma-oblucheniia i 239Pu.