title: Effect of duration of PMSG treatment on induction of oestrus, pregnancy rates and the complications of hyper-oestrogenism in dogs.
abstract: In anoestrous bitches, the use of 5 or 10 days of daily PMSG treatments (20 i.u./kg/day) before a single injection of hCG (500 i.u./dog) did not affect the timing of induced pro-oestrus (4-6 days) but did result in a greater incidence of conception (3 of 6 vs 6 of 17), a high rate of successful pregnancy (50% vs 0%), lower preovulatory oestrogen concentrations, and reduced incidence of complications due to hyper-oestrogenism such as thrombocytopenia (0% vs 29%). These results suggest an advantage of 5 over 10 days of priming with PMSG, at the doses used before hCG injection, for induction of fertile oestrus in bitches.
authors.affiliation: Department of Gynecology, Veterinary Medical Faculty of Zurich, Switzerland.
authors.forename: S
authors.initials: S
authors.lastname: Arnold
authors.forename: P
authors.initials: P
authors.lastname: Arnold
authors.forename: P W
authors.initials: PW
authors.lastname: Concannon
authors.forename: R
authors.initials: R
authors.lastname: Weilenmann
authors.forename: M
authors.initials: M
authors.lastname: Hubler
authors.forename: M
authors.initials: M
authors.lastname: Casal
authors.lastname: Döbeli
authors.forename: A
authors.initials: A
authors.lastname: Fairburn
authors.forename: E
authors.initials: E
authors.lastname: Eggenberger
authors.forename: P
authors.initials: P
authors.lastname: Rüsch
mesh_terms: D000818:Animals; D006063:Chorionic Gonadotropin / Q000494:pharmacology; D004285:Dogs / Q000502:physiology*; D004958:Estradiol / Q000097:blood; D004971:Estrus / Q000187:drug effects*; D005260:Female; D006064:Gonadotropins, Equine / Q000494:pharmacology* / Q000633:toxicity; D010062:Ovulation Induction; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000502:physiology*; D011374:Progesterone / Q000097:blood; D013921:Thrombocytopenia / Q000139:chemically induced; D013997:Time Factors; D014592:Uterine Hemorrhage / Q000139:chemically induced
chemical_list: D006063:Chorionic Gonadotropin; D006064:Gonadotropins, Equine; D011374:Progesterone; D004958:Estradiol