title: Premenstrual syndrome in a group of hysterectomized women of reproductive age with intact ovaries.
abstract: In this prospective study 13 women of reproductive age, unselected with regard to the presence of premenstrual syndrome (PMS) and hysterectomized but with intact ovaries, eight variables were rated as indicative of PMS on visual analog scales (VAS) for 35 consecutive days. Their menstrual cycles were subsequently reconstructed in relation to the luteinizing hormone (LH) surge as pin-pointed in urine samples and confirmed with progesterone in saliva. The aim of the study was to investigate PMS apart from psychological and psychosocial factors and to compare prospective and retrospective ratings of PMS. Retrospectively, 50% of the participants reported having had both somatic and mood changes typical of PMS, but only 3/13 were found to have PMS according to prospective ratings. Symptoms of PMS were absent in one woman according to retrospective ratings and in 4/13 with prospective ratings. There was no significant correlation between retrospective and prospective ratings of PMS. The results indicate that PMS does exist apart from psychological and psychosocial factors.
authors.affiliation: Department of Obstetrics and Gynecology, Huddinge University Hospital, Karolinska Institutet, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: Silber
authors.forename: K
authors.initials: K
authors.lastname: Carlström
authors.forename: B
authors.initials: B
authors.lastname: Larsson
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007986:Luteinizing Hormone / Q000097:blood; D008597:Menstrual Cycle / Q000502:physiology; D010053:Ovary / Q000503:physiopathology*; D011183:Postoperative Complications / Q000209:etiology*; D011293:Premenstrual Syndrome / Q000209:etiology*; D011374:Progesterone / Q000097:blood; D011446:Prospective Studies; D012189:Retrospective Studies
chemical_list: D011374:Progesterone; D007986:Luteinizing Hormone