[Immunochemical findings in the cerebrospinal fluid in patients with inflammatory demyelinating polyradiculoneuropathy].
The aim of the study was to check the hypothesis of involvement of the structure of the central nervous system on the basis of the analysis of the integrity of blood-brain barrier and the degree of IgG synthesis in the intrathecal space of patients with inflammatory demyelinization polyradiculoneuropathy. The study involved 27 patients with acute and 14 patients with chronic inflammatory demyelinization polyradiculoneuropathy. The analysis of liquor was performed in different stages of the disease. The results have shown that in the acute phase, in the phase of the maximal functional deficit there are signs of damaged integrity of the blood-brain barrier but without signs of increased intrathecal IgG synthesis. It has been concluded that there are no reliable signs of increased immunologic activity in the intrathecal space of patients with inflammatory demyelinization polyradiculoneuropathy.
Ivanisević
V
V
Jovicić
A
A
Mijusković
Z
Z
Magdić
B
B
D000328:Adult; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis; D003711:Demyelinating Diseases / Q000134:cerebrospinal fluid / Q000276:immunology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid*; D008297:Male; D008875:Middle Aged
D002556:Cerebrospinal Fluid Proteins; D007074:Immunoglobulin G
Imunohemijski nalaz u likvoru bolesnika sa inflamatornom demijelinizacionom poliradikuloneuropatijom.