[The effect of donor conditioning and perioperative management of recipients on the initial and late function of kidney transplants].
On the basis of 88 consecutive cadaveric renal transplants, multiple variables concerning donor conditioning and perioperative recipient management which may have an influence on the occurrence of acute tubular necrosis (ATN), were analysed and their impact on long-term results assessed. Cold ischaemia time turned out to be the greatest risk factor and was seven hours shorter in patients with good initial function when compared with patients with ATN. Although actual one-year graft survival was similar in both groups, the postoperative course was more complicated in the ATN group and management more onerous. Furthermore, two patients of the initial non-function group died of complications directly related to renal replacement therapy. Seventeen hours cold ischaemia time was associated with more than 80% initial function. This time is sufficient to allow careful tissue typing and organ transportation.
Königsrainer
A
A
Abteilung für Transplantationschirurgie, I. Universitätsklinik für Chirurgie, Innsbruck.
Ofner
D
D
Wieser
C
C
Bösmüller
C
C
Koller
J
J
Margreiter
R
R
D058186:Acute Kidney Injury / Q000209:etiology*; D003080:Cold Temperature; D006801:Humans; D007511:Ischemia; D007668:Kidney / Q000098:blood supply; D016030:Kidney Transplantation; D007683:Kidney Tubular Necrosis, Acute / Q000453:epidemiology / Q000209:etiology*; D012307:Risk Factors; D013997:Time Factors; D014019:Tissue Donors
Einfluss von Spenderkonditionierung und perioperativem Management des Empfängers auf die Initial- und Spätfunktion nach Nierentransplantation.