Quantitative structure-activity relationship studies on some anticancerous, antiviral and cytostatic agents.
QSAR studies using molecular connectivity and van der Waal volume have been performed on a new series of hydroxyguanidine derivatives and a series of isoindolediones. Regression analysis has shown that anticancer and antiviral activity of hydroxyguanidines as well as cytostatic activity of isoindolediones correlate well with both the structural parameters.
Pandey
C
C
Dwivedi
K P
KP
Yadava
G D
GD
Singh
V K
VK
Srivastava
A K
AK
Agrawal
V K
VK
D000970:Antineoplastic Agents; D000998:Antiviral Agents; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D013329:Structure-Activity Relationship
D000970:Antineoplastic Agents; D000998:Antiviral Agents