[Theophylline poisoning in childhood: depurative therapy using a combination of activated charcoal and a saline cathartic].
The Authors describe two cases of theophylline poisoning and discuss advantages of activated charcoal and magnesium hydroxide therapy. This treatment seems to be better in patients for whom hemoperfusion could be delayed. In fact, activated charcoal can determine a real decrease in serum theophylline as experimental data show. Patients who overdose with slow release theophylline preparation should receive multiple oral doses of activated charcoal; they should also receive multiple oral doses of cathartic, both saline or sorbitol like. There is a lack of references about the activated charcoal plus magnesium hydroxide regimen particularly in childhood. The Authors discuss their own experience.
Chiossi
M
M
Rosati
U
U
Renna
S
S
Lattere
M
M
De Santis
L
L
D000293:Adolescent; D002400:Cathartics / Q000008:administration & dosage / Q000627:therapeutic use; D002606:Charcoal / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008274:Magnesium / Q000627:therapeutic use*; D008276:Magnesium Hydroxide / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D013806:Theophylline / Q000506:poisoning*
D002400:Cathartics; D002606:Charcoal; D013806:Theophylline; D008274:Magnesium; D008276:Magnesium Hydroxide
L'avvelenamento da teofillina in età pediatrica: terapia depurativa con associazione di carbone vegetale attivato e catartico salino.