title: [Lyophilized homologous bone grafts in middle ear surgery: new perspectives].
abstract: The authors share their experience of the use of allografts in the reconstruction of the tympano-ossicular chain. The implants were cut from the cortical substance of the long bone in patients deceased for a maximum of six hours; the donors were tested for syphilis, hepatitis, AIDS, systemic diseases or a neoplasm. These bone allografts were cut to size, degreased, demineralized, frozen and then lyophilized in order to be presented to the surgeon in a sterile container (Bone Bank). The implants were all tolerated well. The anatomical results were satisfactory. Optical microscopic studies showed that the implant was: a) covered with mucosa, b) full of osteoblasts and c) the site of a bone neoformation. Experimental research is currently underway in order to perfect the implant preparation methodology.
authors.forename: J P
authors.initials: JP
authors.lastname: Maisin
authors.forename: E
authors.initials: E
authors.lastname: Munting
authors.forename: C
authors.initials: C
authors.lastname: Delloye
authors.forename: M
authors.initials: M
authors.lastname: Gersdorff
mesh_terms: D016025:Bone Transplantation; D002781:Cholesteatoma / Q000601:surgery*; D002908:Chronic Disease; D005612:Freeze Drying; D006801:Humans; D010033:Otitis Media / Q000601:surgery*; D012086:Reoperation; D014433:Tympanoplasty
vernacular_title: Les homogreffes osseuses lyophilisées dans la chirurgie de l'oreille moyenne: nouvelles perspectives.