Evidence that the reflex vagal bradycardia caused by i.v. phenyl biguanide is mediated by central 5-HT1A receptors.
Bogle
R G
RG
Academic Department of Pharmacology, Royal Free Hospital School of Medicine, Hampstead, London.
Ramage
A G
AG
D000818:Animals; D001645:Biguanides / Q000008:administration & dosage / Q000494:pharmacology*; D006339:Heart Rate / Q000187:drug effects*; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D007275:Injections, Intravenous; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D011985:Receptors, Serotonin / Q000187:drug effects / Q000502:physiology*; D012018:Reflex / Q000187:drug effects*
D001645:Biguanides; D007004:Hypoglycemic Agents; D011985:Receptors, Serotonin; C008846:phenyl biguanide