title: [Humoral and cellular indices of nonspecific resistance in viral hepatitis A and ascorbic acid].
abstract: A total of 260 patients aged 15 to 57 years with virus hepatitis A were examined over time for some indicators of humoral and cellular immunity (serum IgA, IgM, IgG, the phagocytic number and indicator of the completeness of neutrophil phagocytosis, cytochemical content of ribonucleic and deoxyribonucleic acids in blood leukocytes). The immunological indicators were determined in two patients' groups after intake per os of 300 mg/day of ascorbic acid for 2-3 weeks and without its administration. It has been established that in virus hepatitis A, vitamin C exerts a remarkable immunomodulating action. In view of this fact, it should be necessarily included into multimodality treatment of patients suffering from pathology under consideration.
authors.forename: V S
authors.initials: VS
authors.lastname: Vasil'ev
authors.forename: V I
authors.initials: VI
authors.lastname: Komar
authors.forename: N I
authors.initials: NI
authors.lastname: Kisel'
mesh_terms: D000276:Adjuvants, Immunologic; D000293:Adolescent; D000328:Adult; D000917:Antibody Formation / Q000187:drug effects / Q000276:immunology; D001205:Ascorbic Acid / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D006506:Hepatitis A / Q000276:immunology* / Q000628:therapy; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects / Q000276:immunology; D008875:Middle Aged
chemical_list: D000276:Adjuvants, Immunologic; D001205:Ascorbic Acid
vernacular_title: Gumoral'nye i kletochnye pokazateli nespetsificheskoĭ rezistentnosti pri virusnom gepatite A i askorbinovaia kislota.