[Serum apolipoprotein and lipoprotein levels in patients with diabetes mellitus type 2].
Lipid disturbances were evaluated in type II diabetes comparing the results of determinations of total cholesterol and HDL-cholesterol with apolipoprotein A and B levels. The study was carried out in 32 diabetics with type II disease with mean duration 7 +/- 9 years, 15 males and 17 females, and in 30 controls. In all cases postprandial glycaemia, haemoglobin A1C, total cholesterol concentration (by the Liebermann-Burchardt method), HDL-cholesterol (by the Błaszczyszyn method), triglycerides (by the enzymatic method), an apolipoprotein A and B (by Mancini radial immunodiffusion method using a Bio-Merieux kit) were determined. A significant correlation was demonstrated between the concentrations of cholesterol and apolipoprotein A, on the one hand, and blood glucose level, on the other, and apolipoprotein A was found to be a better indicator of lipid disturbances in the aspect of diabetes control then apolipoprotein B. The latter was a better indicator of lipid disturbances in diabetes connected with obesity, than total cholesterol.
Gosiewska
A
A
Zarzycki
W
W
Depta
K
K
Składanek
J
J
Kinalski
M
M
Lopaczyński
W
W
D000328:Adult; D000368:Aged; D001053:Apolipoproteins / Q000097:blood*; D001054:Apolipoproteins A / Q000097:blood; D001055:Apolipoproteins B / Q000097:blood; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood* / Q000172:deficiency; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000209:etiology*; D007009:Hypolipoproteinemias / Q000209:etiology*; D008297:Male; D008875:Middle Aged
D001053:Apolipoproteins; D001054:Apolipoproteins A; D001055:Apolipoproteins B; D008076:Cholesterol, HDL; D002784:Cholesterol
Apolipoproteiny i lipoproteiny w surowicy krwi chorych na cukrzyce typu II.