title: Visual impairment in a case of juvenile Paget's disease with pseudoxanthoma elasticum: an eleven year follow up.
abstract: An 11-year follow-up of a child presenting with Paget's disease of bone, and who subsequently developed pseudoxanthoma elasticum, is described. The influence of therapy on the ocular manifestations was disappointing. Calcitonin did not prevent the occurrence or progression of angioid streaks, and Argon laser photocoagulation of complicating subretinal neovascular membranes failed to prevent visual loss.
authors.affiliation: Department of Ophthalmology, Southern General Hospital, Victoria Infirmary, Glasgow, Scotland.
authors.forename: K W
authors.initials: KW
authors.lastname: Sharif
authors.forename: W M
authors.initials: WM
authors.lastname: Doig
authors.forename: F P
authors.initials: FP
authors.lastname: Kinsella
mesh_terms: D001766:Blindness / Q000209:etiology; D002116:Calcitonin / Q000627:therapeutic use; D002648:Child; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008028:Light Coagulation; D008297:Male; D010001:Osteitis Deformans / Q000150:complications* / Q000188:drug therapy; D011561:Pseudoxanthoma Elasticum / Q000150:complications*; D012164:Retinal Diseases / Q000209:etiology; D014786:Vision Disorders / Q000209:etiology* / Q000473:pathology; D014792:Visual Acuity
chemical_list: D002116:Calcitonin