Goniotriol from Goniothalamus giganteus.
The known styrylpyrone, goniotriol, has been isolated from Goniothalamus giganteus. Its bioactivities are reported, and its structure and relative stereochemistry have been determined by X-ray crystallography as 6R-(7R,8R-dihydro-7,8-dihydroxystyryl)-5S,6R-dihydro-5-hydroxy-2-p yrone.
Alkofahi
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Department of Medicinal Chemistry and Pharmacognosy, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayett, Indiana 47907.
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McKenzie
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Byrn
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McLaughlin
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D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification; D001156:Artemia / Q000187:drug effects; D003461:Crystallography; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D015394:Molecular Structure; D010944:Plants / Q000032:analysis*; D011714:Pyrans / Q000302:isolation & purification*; D011753:Pyrones / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic; D011714:Pyrans; D011753:Pyrones; C062903:goniotriol