[In-vitro incorporation of BUDR by the prostate and by human urothelium and immunohistological detection in plastic-encased sections].
The measurement of the S phase fraction, essential parameter of cell proliferation, may be done through the immunohistochemical revelation of BUDR incorporated in the cells. The technique is illustrated. The advantages of in vitro incorporation as compared with in vivo injection as discussed. Easier than autoradiography, this method may be useful, in clinical practice, to study the aggressiveness of cancer tissues.
Bonnet
P
P
Dombrowicz
D
D
D001973:Bromodeoxyuridine / Q000032:analysis*; D004727:Endothelium / Q000032:analysis* / Q000166:cytology; D006801:Humans; D007150:Immunohistochemistry; D007399:Interphase; D008297:Male; D011467:Prostate / Q000032:analysis* / Q000166:cytology
D001973:Bromodeoxyuridine
Incorporation in vitro du BUDR par la prostate et l'urothélium humains et révélation immunohistologique sur coupes inclues dans le plastic.