title: Increased muscle tension and reduced elasticity of affected muscles in recent-onset Graves' disease caused primarily by active muscle contraction.
abstract: In 3 patients with Graves' disease of recent onset, length-tension diagrams were made during surgery for squint under eyedrop anesthesia. The affected muscles were found to be very stiff when the other eye looked straight ahead. It was expected that these stiff muscles would be able to shorten to some extent but would be unable to lengthen, due to fibrosis of the muscle. We found that the affected muscles did not shorten very much when the other eye looked into the field of action of the muscle. Unexpectedly however, they lengthened considerably when the other eye looked out of the field of action of the muscle. This finding implies that the raised muscle tension and reduced elasticity of affected muscles in these cases of Graves' disease of recent onset were primarily caused by active muscle contraction, not by fibrosis.
authors.affiliation: Universitäts-Augenklinik, Freiburg, BRD.
authors.forename: H J
authors.initials: HJ
authors.lastname: Simonsz
authors.forename: G
authors.initials: G
authors.lastname: Kommerell
mesh_terms: D004172:Diplopia / Q000150:complications; D004548:Elasticity; D005133:Eye Movements; D005260:Female; D006111:Graves Disease / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction; D009801:Oculomotor Muscles / Q000503:physiopathology*; D013285:Strabismus / Q000150:complications / Q000601:surgery; D013718:Tensile Strength; D014792:Visual Acuity