title: [Total synthesis and properties of prostaglandins. XXI. Synthesis of a 4,4-dimethyl-4-sil analog of 11-deoxyprostaglandin E1].
abstract: Total synthesis of a new prostaglandin analogue, 11-deoxy-4,4-dimethyl-4-sil-prostaglandin E1, is carried out through synthesis of a silicon-containing alpha-chain precursor and a 2-substituted cyclopentenone derivative followed by their cuprate-induced interaction.
authors.forename: V R
authors.initials: VR
authors.lastname: Korits
authors.forename: S Kh
authors.initials: SKh
authors.lastname: Rozite
authors.forename: I V
authors.initials: IV
authors.lastname: Turovskiĭ
authors.forename: Ia F
authors.initials: IaF
authors.lastname: Freĭmanis
mesh_terms: D000527:Alprostadil / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D055598:Chemical Phenomena; D002621:Chemistry; D006868:Hydrolysis; D011459:Prostaglandins E, Synthetic / Q000138:chemical synthesis*
chemical_list: D011459:Prostaglandins E, Synthetic; C062943:11-deoxy-4,4-dimethyl-4-silaprostaglandin E1; D000527:Alprostadil; C034008:11-deoxyprostaglandin E1
vernacular_title: Total'nyĭ sintez i svoĭstva prostaglandinov. XXI. Sintez 4,4-dimetil-4-sila-analoga 11-dezoksiprostaglandina E1.