title: [Intra-arterial chemotherapy of ORL cancer. Value of an implantable infusion system and scintigraphic monitoring].
abstract: The technical difficulties and complications related to arterial catheterisation have inhibited the development of regional chemotherapy in ENT oncology despite the numerous theoretical advantages associated with this method. We report our recent experience with a completely implantable infusion system; 12 systems were inserted, 11 unilateral and 1 bilateral. Treatment was carried out in 8 patients and the perfect biocompatibility of the material was confirmed. Good distribution of the infusion to the tumor zone and lack of cerebral diffusion were confirmed before treatment using an infusion of free Technetium.
authors.affiliation: Service de Chirurgie ORL et Cervico-faciale, Centre Antoine-Lacassagne, Nice.
authors.forename: J
authors.initials: J
authors.lastname: Santini
authors.forename: O
authors.initials: O
authors.lastname: Dassonville
authors.forename: C
authors.initials: C
authors.lastname: Serra
authors.forename: M N
authors.initials: MN
authors.lastname: Falewee
authors.forename: J
authors.initials: J
authors.lastname: Darcourt
authors.forename: M
authors.initials: M
authors.lastname: Schneider
authors.forename: F
authors.initials: F
authors.lastname: Demard
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000188:drug therapy*; D002945:Cisplatin / Q000008:administration & dosage; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D015918:Infusion Pumps, Implantable; D007261:Infusions, Intra-Arterial / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged; D010039:Otorhinolaryngologic Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011877:Radionuclide Imaging; D013997:Time Factors
chemical_list: D002945:Cisplatin; D005472:Fluorouracil
vernacular_title: Chimiothérapie intra-artérielle des cancers ORL. Apports d'un système d'infusion implantable et de la surveillance scintigraphique.