title: [Successful local treatment of nail psoriasis with 5-fluorouracil].
abstract: Topical application of 5-fluorouracil (5-FU) has proved effective in the therapy of psoriasis of the nail. Over a period of 6 months, we treated 114 patients with 1% 5-FU liquid and 59 patients with 20% urea plus 1% 5-FU cream twice daily. An improvement of more than 50% of the clinical signs of psoriasis, such as oil spots, subungual hyperkeratosis, and combined signs, was achieved after treatment with urea + 5-FU cream.
authors.forename: K
authors.initials: K
authors.lastname: Fritz
mesh_terms: D000287:Administration, Topical; D005500:Follow-Up Studies; D006801:Humans; D009260:Nail Diseases / Q000188:drug therapy*; D011565:Psoriasis / Q000188:drug therapy*
vernacular_title: Erfolgreiche Lokalbehandlung der Nagelpsoriasis mit 5-Fluorouracil.