[The platelet factor 4 content of the blood in induced myocardial ischemia in patients with stable stenocardia].
Seventeen patients were studied: 10 with stable angina and coronary atherosclerosis, and 7 with "intact" coronary arteries (a control group). All patients underwent coronarography and catheterization of the coronary sinus. Blood samples were obtained from the left ventricle and coronary sinus in 3 points: at rest, peak pacing, 10 min after pacing. All patients with stable angina had positive atrial pacing test (pain and/or ECG deviations and lactate production), in control group similar changes were not observed. However, no statistically significant difference was found in platelet factor (IV) 4 levels between the groups and following pacing; the level of platelet factor IV was near 90 ng/ml. It is concluded that patients with stable angina during pacing-induced ischemia had no significant platelet activation, which may provoke thrombotic events.
Pavlov
N A
NA
Pomerantsev
E V
EV
Masenko
V P
VP
Kupriianenko
T I
TI
D000328:Adult; D000787:Angina Pectoris / Q000097:blood* / Q000150:complications; D003327:Coronary Disease / Q000097:blood* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009449:Neurocirculatory Asthenia / Q000097:blood; D010007:Osteochondritis / Q000097:blood; D015539:Platelet Activation / Q000502:physiology; D010978:Platelet Factor 4 / Q000032:analysis*; D013166:Spondylitis / Q000097:blood
D010978:Platelet Factor 4
Soderzhanie 4-go faktora trombotsitov v krovi na fone indutsirovannoĭ ishemii miokarda u bol'nykh stabil'noĭ stenokardieĭ.