title: [Potential CNS-active tricyclic compounds with a bridged middle ring. 9,10-Epoxy-9,10-dihydroanthracenes with dialkylamino side chain].
abstract: As a continuation of our efforts on the synthesis of 9,10-epoxy-9,10-dihydroanthracene compounds with basic side chain several substituted 9-amino-methyl derivatives have been prepared by Diels-Alder cyclization of substituted benzo[c]furanes with benzyne. The benzo[c]furanes were obtained by vacuum flash thermolysis of 1,4-epoxy-1,2,3,4-tetrahydronaphthalene-1-carbonamides which were produced by Diels-Alder reaction of 2-furan-carbonamides with benzyne and by subsequent hydrogenation.
authors.forename: H F
authors.initials: HF
authors.lastname: Linde
authors.forename: G
authors.initials: G
authors.lastname: Cramer
mesh_terms: D000873:Anthracenes / Q000138:chemical synthesis* / Q000494:pharmacology; D002491:Central Nervous System Agents / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D004852:Epoxy Compounds / Q000138:chemical synthesis* / Q000494:pharmacology; D004988:Ethers, Cyclic / Q000138:chemical synthesis*
chemical_list: D000873:Anthracenes; D002491:Central Nervous System Agents; D004852:Epoxy Compounds; D004988:Ethers, Cyclic
vernacular_title: Potentiell ZNS-wirksame, tricyclische Verbindungen mit verbrücktem Mittelring, 2.Mitt.: 9,10-Epoxy-9,10-dihydroanthracene mit Dialkyl-aminomethyl-Seitenkette.