Anterior segment vascular casting.
Vascular corrosion casting provides a permanent three-dimensional record of the deeper vasculature of the anterior segment whereas fluorescein angiography allows clinical examination of superficial vessels. Morphological findings on scanning electron microscopy of vascular casts of the anterior segment in sheep are presented and compared with that of man by casting techniques. Sheep illustrate the basic mammalian anterior segment vascular architecture but lack anterior ciliary arteries which connect with the deeper collateral arterial circles. The casting technique is described and its use to answer comparative anatomical, pathological and clinical questions explained. These techniques are being applied to examine changes to the anterior ciliary arteries and the deeper vessels following strabismus surgery in an animal model. Scanning electron microscopy of vascular corrosion casts has given a new dimension to micro-vascular anatomy.
Olver
J M
JM
Institute of Ophthalmology, London.
McCartney
A C
AC
D000818:Animals; D000869:Anterior Eye Segment / Q000098:blood supply* / Q000648:ultrastructure; D002196:Capillaries / Q000648:ultrastructure; D002924:Ciliary Body / Q000098:blood supply / Q000648:ultrastructure; D006654:Histology, Comparative; D006801:Humans; D007498:Iris / Q000098:blood supply / Q000648:ultrastructure; D008722:Methods; D008855:Microscopy, Electron, Scanning; D012756:Sheep; D013285:Strabismus / Q000601:surgery