Changes of T-kininogen levels in plasma and liver during development of rats.
T-kininogen levels of plasma and liver were measured in rats during development by RIA. We found that higher levels of T-kininogen in plasma and liver of neonates and of the mother rats at around term. The plasma level of mature male rats was as low as 1/5 to 1/2 of that of mature female rats. T-kininogen levels in male and female rats increased after treatment with estradiol, indicating that sex hormones may regulate the physiological level of T-kininogen in rats.
Hayashi
I
I
Department of Pharmacology, School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan.
Kusunoki
A
A
Nagashima
Y
Y
Hayashi
M
M
Oh-ishi
S
S
D000375:Aging / Q000097:blood*; D000818:Animals; D005260:Female; D007704:Kininogens / Q000032:analysis* / Q000097:blood; D008099:Liver / Q000254:growth & development*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013045:Species Specificity
D007704:Kininogens