[Shape and amplitude of stimulating postsynaptic potentials in a neuronal model with an N-shaped volt-ampere characteristic of the dendritic membrane].
We developed a model of a neuron with N-shaped current--voltage characteristic of dendritic membrane and studied the change of shape and amplitude of excitatory postsynaptic potentials (EPSP) when changing the place of synapses on dendrites. Local EPSP can activate slow inward current. Consequently, the EPSP amplitude does not always diminish when the rise- and decay-time increases. In some cases the rise- and decay-time of a more distant synapse may become shorter than that of the more approximate one. The common method of judging about the location of synapses by means of the shape of EPSPs may be wrong.
Baginskas
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Gutman
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D002462:Cell Membrane / Q000502:physiology; D003712:Dendrites / Q000502:physiology*; D008564:Membrane Potentials; D009474:Neurons / Q000502:physiology*; D013569:Synapses / Q000502:physiology*
Forma i amplituda vozbuzhdaiushchikh postsinapticheskikh potentsialov na modeli neĭrona s N-obraznoĭ vol't-ampernoĭ kharakteristikoĭ dendritnoĭ membrany.