title: Goniotriol from Goniothalamus giganteus.
abstract: The known styrylpyrone, goniotriol, has been isolated from Goniothalamus giganteus. Its bioactivities are reported, and its structure and relative stereochemistry have been determined by X-ray crystallography as 6R-(7R,8R-dihydro-7,8-dihydroxystyryl)-5S,6R-dihydro-5-hydroxy-2-p yrone.
authors.affiliation: Department of Medicinal Chemistry and Pharmacognosy, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayett, Indiana 47907.
authors.forename: A
authors.initials: A
authors.lastname: Alkofahi
authors.forename: W W
authors.initials: WW
authors.lastname: Ma
authors.forename: A T
authors.initials: AT
authors.lastname: McKenzie
authors.forename: S R
authors.initials: SR
authors.lastname: Byrn
authors.forename: J L
authors.initials: JL
authors.lastname: McLaughlin
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification; D001156:Artemia / Q000187:drug effects; D003461:Crystallography; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D015394:Molecular Structure; D010944:Plants / Q000032:analysis*; D011714:Pyrans / Q000302:isolation & purification*; D011753:Pyrones / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D011714:Pyrans; D011753:Pyrones; C062903:goniotriol