[Determination of superoxide dismutase (SOD) in serum of cancer patients by microchemical luminescence].
Superoxide dismutase (SOD) activity in blood of cancer patients were detected by microchemical luminescence. The results showed that SOD activity was closely related to the development of tumor. 151 cancer patients were divided into 5 groups: lung cancer, digestive tract cancer, breast cancer, gynecologic cancer and other cancers. The level of SOD in the blood in each group was higher than that in healthy adult controls. There was significant difference in the positive rate: 73.68% in breast cancer, 60.78% in digestive tract cancer, 60% in lung cancer, 51.52% in gynecologic cancer and 73.91% in other cancers. Thirty-one of these patients had low SOD due to radiotherapy or chemotherapy before determination. The important role of SOD in the development of cancer and its mechanism of preventing cancer are preliminarily analysed and discussed.
Dai
R
R
Liaoning Tumor Institute, Shenyang.
D001943:Breast Neoplasms / Q000201:enzymology; D004067:Digestive System Neoplasms / Q000201:enzymology; D005260:Female; D005833:Genital Neoplasms, Female / Q000201:enzymology; D006801:Humans; D008163:Luminescent Measurements; D008175:Lung Neoplasms / Q000201:enzymology; D008297:Male; D009369:Neoplasms / Q000201:enzymology*; D013482:Superoxide Dismutase / Q000097:blood*
D013482:Superoxide Dismutase