title: [Modern principles of the treatment of testicular tumors].
abstract: The modern principles of treatment of patients with germinative tumors of the testis are discussed. Essential are precise morphologic diagnosis and exact determination of the stage of the disease. Preference is given to the so called surgical-pathological staging, because it furnishes major objective information. Of the noninvasive methods of examination major value have computer axial tomography, measurement of the serum alpha-fetoprotein, human choriongonadotropin and SB1 levels, lymphography and pulmonary tomography. The role of tumor markers as criteria for early diagnosis of relapses and objective assessment of the effect of treatment is emphasized. The place of chemotherapy depending on the histologic variant and the stage of the process is determined. The results of modern chemotherapeutic schemes, which have shown statistically greatest effectiveness are discussed. The place of supra- and infrahilar lymph dissection as method of diagnosis and treatment is arguable. Some records (randomized) for treatment of germinative tumors of the testis, which might serve as practical guidance are presented.
authors.forename: Kh
authors.initials: Kh
authors.lastname: Kumanov
authors.forename: V
authors.initials: V
authors.lastname: Ianev
authors.forename: Ia
authors.initials: Ia
authors.lastname: Ianev
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D003131:Combined Modality Therapy; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D009367:Neoplasm Staging; D011879:Radiotherapy Dosage; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*
chemical_list: D014408:Biomarkers, Tumor
vernacular_title: Sŭvremenni printsipi na lechenie na testikuliarnite tumori.