Treatment with locally applied mitoxantrone.
In 30 patients mitoxantrone was administered via an intracavitary route intraperitoneally, intrapleurally or intrapericardially. From 13 patients with malignant pleural effusion 5 showed a complete and 3 a partial remission. 2 of 2 patients with pericardial effusion showed a complete remission. From 16 patients with peritoneal carcinosis 4 showed a complete and 3 a partial remission.
Kuhn
K
K
Medizinischen Klinik II für Hämatologie, Onkologie und Immunologle, St. Johannes-Hospital, Duisburg, FRG.
Purea
H
H
Selbach
J
J
Westerhausen
M
M
D002408:Catheters, Indwelling; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D008479:Mediastinal Neoplasms / Q000188:drug therapy / Q000556:secondary*; D008942:Mitoxantrone / Q000008:administration & dosage* / Q000009:adverse effects; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy; D010496:Pericardium / Q000187:drug effects; D010534:Peritoneal Neoplasms / Q000188:drug therapy / Q000556:secondary*; D010997:Pleural Neoplasms / Q000188:drug therapy / Q000556:secondary*
D008942:Mitoxantrone