Cyclosporin A and psoriasis: a thermographic study.
The thermographic method permits the making of a rigorous evaluation of the cutaneous blood flow by means of thermal recovery times after thermostimulation at 5 degrees C for 20 sec. The aim of the present study was to examine the blood flow of the psoriatic skin of 7 patients before and after a course of cyclosporin therapy, by means of this method. The results show a constant, initial hyperthermia with precocious thermal recovery times, in comparison with the healthy perilesional skin. Following therapy, a prolongation of the thermal recovery time was observed in all of the patients, together with a significant improvement of the dermatosis.
Ippolito
F
F
Istituto Dermatologico S. Maria e S. Gallicano, Rome, Italy.
Di Carlo
A
A
Carducci
M
M
Leone
G
G
Frascione
P
P
D003524:Cyclosporins / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D011565:Psoriasis / Q000188:drug therapy* / Q000503:physiopathology; D012039:Regional Blood Flow / Q000187:drug effects; D012867:Skin / Q000098:blood supply*; D013817:Thermography / Q000379:methods*
D003524:Cyclosporins