[The prevalence of the HBsAg carrier state among pregnant women and its effect on newborn infants. IV. Our experience in using hepatitis B vaccine and hepatitis B immunoglobulin to immunize infants born to mothers who carry HBsAg].
59 children, born to mothers--carriers of HBsAg were immunized with hepatitis B vaccine (Gen HB-VAX) and hepatic B immunoglobulin (H-BIG) during 1988 in the municipality of Pleven. The results showed that GEN H-B-VAX possessed high immunological and epidemiological effect, manifested by the presence of anti-HBs in all examined children one month after conclusion of immunization. No diseases due to virus hepatitis B as well as persisting antigenemia were observed during the indicated 7-month period. Simultaneously there were one case with virus hepatitis B and 6 cases with persisting antigenemia in the control group of newborn infants.
Iliev
B
B
Stambolov
B
B
Marinova
E
E
Khitkova
Kh
Kh
Khristov
M
M
D000328:Adult; D015415:Biomarkers / Q000097:blood; D002031:Bulgaria / Q000453:epidemiology; D002353:Carrier State / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control; D006514:Hepatitis B Surface Antigens / Q000097:blood*; D006801:Humans; D007114:Immunization / Q000379:methods; D007116:Immunization, Passive; D007223:Infant; D007231:Infant, Newborn; D011247:Pregnancy; D014761:Viral Hepatitis Vaccines / Q000276:immunology*
D015415:Biomarkers; D006514:Hepatitis B Surface Antigens; D014761:Viral Hepatitis Vaccines
Razprostranenieto na nositelstvoto na HBsAg sred bremenni zheni i vliianieto mu vŭrkhu novorodenite detsa. IV. Nashiiat opit ot prilozhenieto na khepatit B vaksina i khepatiten B immunoglobulin za imunizirane na detsa, rodeni ot maĭki, nositelki na HBsAg.