title: [Individualization of the dosage of high-dose methotrexate by assaying plasma concentration. Therapeutic value in osteogenic sarcoma].
authors.affiliation: Unité Oncologie Pédiatrique, Hôpital Robert-Debré, Paris, France.
authors.forename: N
authors.initials: N
authors.lastname: Delepine
authors.forename: J C
authors.initials: JC
authors.lastname: Desbois
authors.forename: G
authors.initials: G
authors.lastname: Delepine
authors.forename: H
authors.initials: H
authors.lastname: Cornille
authors.forename: A
authors.initials: A
authors.lastname: Astier
authors.forename: S
authors.initials: S
authors.lastname: Alkallaf
mesh_terms: D001859:Bone Neoplasms / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage* / Q000097:blood / Q000627:therapeutic use; D012516:Osteosarcoma / Q000188:drug therapy*; D013997:Time Factors
chemical_list: D008727:Methotrexate
vernacular_title: Individualisation de posologie de méthotrexate haute dose par le dosage des concentrations plasmatiques. Intérèt thérapeutique dans le sarcome ostéogénique.