[Hyperplasia of the adrenergic nerve fibers of the vessels and myocardium in rats with spontaneous hypertension].
Adrenergic innervation of the myocardium vessels was morphometrically studied in 4-, 8-, 12- and 20-week-old spontaneously hypertensive rats (SHR). The increase of cardiac adrenergic nerves was found in the early period of persistent hypertension (in 12-week-old SHR). In the vessels this increase was more pronounced and started earlier, at prehypertensive stage (in 4-week-old SHR). The data obtained confirm the hyperplasia of the terminal part of the sympathetic nervous system, this reflecting the increased sympathetic influence on cardiovascular system in hypertension.
Vaganova
M E
ME
Gor'kova
S I
SI
D000320:Adrenergic Fibers / Q000648:ultrastructure*; D000375:Aging; D000818:Animals; D001835:Body Weight; D006321:Heart / Q000294:innervation*; D006965:Hyperplasia / Q000473:pathology; D006973:Hypertension / Q000473:pathology*; D008297:Male; D008576:Meningeal Arteries / Q000294:innervation* / Q000648:ultrastructure; D008638:Mesenteric Arteries / Q000294:innervation* / Q000648:ultrastructure; D008854:Microscopy, Electron; D008856:Microscopy, Fluorescence; D009206:Myocardium / Q000648:ultrastructure; D009929:Organ Size; D051381:Rats; D011918:Rats, Inbred SHR / Q000033:anatomy & histology*; D011919:Rats, Inbred Strains / Q000033:anatomy & histology*; D011921:Rats, Inbred WKY
Giperplaziia adrenergicheskikh nervnykh volokon v sosudakh i miokardee u krys so spontannoĭ gipertenzieĭ.