title: Modeling for scaling to humans: time to get serious.
abstract: The subject matter for this 26th Annual Hanford Life Sciences Symposium evolved from the deliberations of a Task Group on Modeling for Scaling to Humans, which was established in January 1986 through the efforts of the Office of Health and Environmental Research of the Department of Energy (OHER/DOE). Several laboratories that utilize animals in radiobiological research sponsored by the OHER/DOE were extensively reviewed in the spring of 1985, and, as a result, OHER recommended establishment of eight task groups designed for selected purposes. The current membership of the Task Group on Modeling for Scaling to Humans is shown in Table 1; Dr. James A. Mewhinney of the Lovelace Inhalation Toxicology Research Institute has been Chairman since these Task Groups were established. Ms. Judy Mahaffey of Battelle. Pacific Northwest Laboratories served as chairperson for this symposium, and the Task Group membership has served as the Program Committee. The OHER/DOE thanks all of them for their work as members of the Task Group as well as for their arranging such a potentially productive and informative meeting.
authors.affiliation: Office of Energy Research, U.S. Department of Energy, Washington, DC 20545.
authors.forename: R G
authors.initials: RG
authors.lastname: Thomas
mesh_terms: D000818:Animals; D006224:Cricetinae; D004285:Dogs; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D051379:Mice; D008954:Models, Biological; D009381:Neoplasms, Radiation-Induced; D010215:Papio; D011830:Radiation Effects; D011868:Radioisotopes; D051381:Rats; D013045:Species Specificity
chemical_list: D011868:Radioisotopes