title: Multiple sclerosis is associated with HLA-DR2 antigen in Spain.
abstract: One hundred and twenty-one Spanish multiple sclerosis patients were typed for HLA antigens. We found a significant increase of HLA-DR2 (p less than 0.004) compared with local normal controls. We confirm similar findings in other Caucasian populations.
authors.affiliation: Department of Immunology, Hospital Ramón y Cajal, Madrid, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Clerici
authors.forename: M
authors.initials: M
authors.lastname: Hernández
authors.forename: M
authors.initials: M
authors.lastname: Fernández
authors.forename: J
authors.initials: J
authors.lastname: Rosique
authors.forename: J
authors.initials: J
authors.lastname: Alvarez-Cermeño
mesh_terms: D000328:Adult; D005260:Female; D006683:HLA-DQ Antigens / Q000032:analysis; D015802:HLA-DR2 Antigen / Q000032:analysis* / Q000235:genetics; D006650:Histocompatibility Testing; D006801:Humans; D015810:Linkage Disequilibrium; D008297:Male; D009103:Multiple Sclerosis / Q000276:immunology*; D010641:Phenotype; D013030:Spain
chemical_list: D006683:HLA-DQ Antigens; C051568:HLA-DQ1 antigen; D015802:HLA-DR2 Antigen