Microbial transformation of 13-ethyl-3-methoxy-8,14-seco-gona-1,3,5(10),9(11)-tetraene-14, 17-dione to its 17-beta hydroxy derivative by Pichia farinosa in pilot plant fermentors.
Parameters for microbial transformation of 13-ethyl-3-methoxy-8, 14-seco-gona-1,3,5 (10), 9(11)-tetraene-14,17-dione to its 17 beta-hydroxy derivative by P. farinosa have been standardised in pilot plant fermentors. The yield of the pure crystalline compound was 80%.
Mehdi
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I
Mandwal
A K
AK
Bhatia
M C
MC
D005285:Fermentation; D006067:Gonanes / Q000378:metabolism*; D009644:Norgestrel / Q000378:metabolism*; D010843:Pichia; D012632:Secosteroids / Q000378:metabolism*; D013237:Stereoisomerism
D006067:Gonanes; D012632:Secosteroids; D009644:Norgestrel; C063748:13-ethyl-3-methoxy-8,14-secogona-1,3,5(10),9(11)-tetraene-14,17-dione