[Significance of HCG injection for ovulation induction and of ovulation prediction factors in the practice of artificial insemination using donor sperm. A randomized study].
This randomised study was carried out on 77 patients who underwent 269 cycles of donor insemination (AID). The randomization was carried out to decide whether HCG should be used or not to provoke ovulation. The results in AID show, in our study, that using HCG in estimating oestradiol makes very little difference. On the other hand, measuring LH and the quality of the sperm that is used for the insemination seem to us to be important, whereas the quality of the cervical mucus is absolutely fundamental. Ultrasound makes it possible to determine the date when the AID should be carried out in difficult cases. The use of HCG to release the oocytes can be discussed when the cervical score is less than 7 when the other parameters are favourable, and in particular when the diameter of the dominant follicle is 18 mm or more. A higher pregnancy rate should be able to be obtained in AID if all parameters are looked at.
Claraz
E
E
Clinique Gynécologique, Hôpital Edouard-Herriot, Lyon.
Frobert
C
C
Brémond
A
A
Cottinet
D
D
D006063:Chorionic Gonadotropin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007315:Insemination, Artificial; D007316:Insemination, Artificial, Heterologous; D010061:Ovulation Detection; D010062:Ovulation Induction; D011379:Prognosis; D011897:Random Allocation
D006063:Chorionic Gonadotropin
Intérêt pour la pratique de l'insémination artificielle avec sperme de donneur de l'injection d'HCG déclenchant et des facteurs de prédiction de l'ovulation. Etude randomisée.