[Grouping of Micromonospora based on their cultural-morphologic features, antibiotic-sensitivity and formation of antibiotics].
500 Micromonospora cultures were subdivided into nine groups on the basis of their cultural-morphological properties, the ability to produce antibiotics of certain chemical classes, and the sensitivity to 18 different antibiotics: aurantiaca (I), cinnamomea (II), cinnamomea-vinacea (III), cinnamomea-olivacea (IV), nigra (V), nigra-violacea (VI), lilacinescens (VII), coerulea (VIII) and brunnea (IX). Cultures belonging to groups I, II, III, V and VI are moderately sensitive to most of the antibiotics and often occur in natural substrates. Black Micromonospora cultures (groups V and VI) mostly produce aminoglycoside antibiotics while brown cultures (groups II and III) form macrolide antibiotics. Cultures belonging to groups IV, VII, VIII and IX have a higher sensitivity to most of the antibiotics and are rarely isolated from natural substrates. These cultures have a weak ability to produce antibiotics.
Bibikova
M V
MV
Ivanitskaia
L P
LP
Singal
E M
EM
Vostrov
S N
SN
D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D004352:Drug Resistance, Microbial; D008847:Micromonospora / Q000145:classification* / Q000187:drug effects / Q000378:metabolism
D000900:Anti-Bacterial Agents
Gruppirovka mikromonospor na osnove sopostableniia ikh kul'tural'no- morfologicheskikh priznakov, antibiotikochuvstvitel'nosti i obrazovaniia antibiotikov.