title: Two unusual cases of metastatic osteosarcoma detected by Tc-99m MDP bone scintigraphy.
abstract: Tc-99m MDP bone scintigraphy is widely used for initial staging and subsequent follow-up of patients with osteosarcoma. Two unusual cases are presented here, one with diffuse pleural metastases and one with diffuse peritoneal metastases. In one case, an abnormal bone scan was the first indication of metastatic disease. Both the metastatic pattern of osteosarcoma and the indications for bone scintigraphy are reviewed.
authors.affiliation: University of Southern California School of Medicine, Los Angeles.
authors.forename: A
authors.initials: A
authors.lastname: Heinle
authors.forename: J A
authors.initials: JA
authors.lastname: Carrasquillo
authors.forename: R D
authors.initials: RD
authors.lastname: Neumann
mesh_terms: D000293:Adolescent; D000328:Adult; D005266:Femoral Neoplasms / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D012516:Osteosarcoma / Q000000981:diagnostic imaging / Q000556:secondary*; D010534:Peritoneal Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D010997:Pleural Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D011877:Radionuclide Imaging; D013669:Technetium Tc 99m Medronate
chemical_list: D013669:Technetium Tc 99m Medronate