Susceptibility of anaerobic bacteria to ALP 201.
The activity of ALP 201 against 350 strains of anaerobic bacteria was determined by an agar dilution method. Its activity was compared with those of piperacillin, cefoxitin, imipenem, clindamycin, metronidazole, and chloramphenicol. ALP 201 and imipenem were the most active agents tested. Based on these results, ALP 201 appears to be a promising antimicrobial agent for anaerobic infections and warrants further clinical investigations.
Nord
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Department of Microbiology, Huddinge University Hospital, Stockholm, Sweden.
Lindmark
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A
Persson
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D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001421:Bacteria, Anaerobic / Q000187:drug effects*; D015780:Carbapenems / Q000494:pharmacology*; D003470:Culture Media; D008826:Microbial Sensitivity Tests
D000900:Anti-Bacterial Agents; D015780:Carbapenems; D003470:Culture Media; C060114:SUN 5555