[Correction of disorders of the system of blood aggregation regulation by ionol in the post-resuscitation period].
In the experiments on white rats resuscitated after a 7-minute mechanical asphyxia, phase disorders in the indices of the system of regulation of aggregate state of the blood in postresuscitation period have been revealed. They appear in the shape of a syndrome of disseminated intravascular blood coagulation with the development of hypercoagulation phase by the 3rd hour. Prophylactic introduction of ionol in a dose of 100 mg/kg in 48, 24 and 1 hour before the experiment prevents the development and progressing of the above syndrome.
Rezin
V A
VA
D000818:Animals; D001780:Blood Coagulation Tests; D002084:Butylated Hydroxytoluene / Q000008:administration & dosage / Q000627:therapeutic use*; D004211:Disseminated Intravascular Coagulation / Q000517:prevention & control*; D051381:Rats; D012151:Resuscitation; D013997:Time Factors
D002084:Butylated Hydroxytoluene
Korrektsiia narusheniĭ sistemy reguliatsii agregatnogo sostoianiia krovi ionolom v postreanimatsionnom periode.