Antibiotic susceptibility of rickettsia and treatment of rickettsioses.
The author describes the in vitro data for antibiotic susceptibility of Rickettsia and Coxiella burnetti. Tetracyclines are still the first antibiotic choice in spotted fevers, typhus and Q fever. In spotted fever a shortened treatment is suggested and the place of macrolide antibiotics, such as Josamycin, in treating children may be evaluated. In Q fever, according to the new biological data, an association of tetracyclines and Rifampin or Quinolones is suggested.
Raoult
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Centre national de reference des rickettsioses, WHO collaborative center for diagnosis and research CHU la Timone, Marseille, France.
D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003381:Coxiella / Q000187:drug effects; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D011247:Pregnancy; D011778:Q Fever / Q000188:drug therapy; D012281:Rickettsia / Q000187:drug effects*; D012282:Rickettsia Infections / Q000188:drug therapy*; D012373:Rocky Mountain Spotted Fever / Q000188:drug therapy; D014437:Typhus, Endemic Flea-Borne / Q000188:drug therapy; D014438:Typhus, Epidemic Louse-Borne / Q000188:drug therapy
D000900:Anti-Bacterial Agents