title: Recent studies on nucleoside H-phosphonothioate and nucleoside methylphosphonothioate synthesis.
abstract: The reaction of suitably protected nucleosides with phosphinic acid in the presence of condensing agents has been investigated and applied for the preparation of nucleoside 3'-H-phosphonothioates. Studies on synthesis and separation of diastereoisomers of nucleoside 3'-methylphosphonothioates are also discussed.
authors.affiliation: Department of Organic Chemistry, Arrhenius Laboratory, University of Stockholm, Sweden.
authors.forename: J
authors.initials: J
authors.lastname: Stawiński
authors.forename: T
authors.initials: T
authors.lastname: Szabó
authors.forename: M
authors.initials: M
authors.lastname: Thelin
authors.forename: E
authors.initials: E
authors.lastname: Westman
authors.forename: R
authors.initials: R
authors.lastname: Zain
mesh_terms: D010721:Phosphinic Acids; D013237:Stereoisomerism; D013873:Thionucleotides / Q000138:chemical synthesis*
chemical_list: D010721:Phosphinic Acids; D013873:Thionucleotides