Effect of herbicide banvel on rabbit vaginal mucus membrane.
Effect of banvel and its active ingredient, dicamba (3,6-dichloro-o-anisic acid) was investigated employing rabbit mucus membrane irritancy test. Inflammatory changes which did not exceed an average score of 2+ were observed in the animals 48 hr after a single intravaginal application of banvel (0.1 ml/rabbit) and dicamba (100 mg/rabbit). Persistent histopathological changes were observed in 1 out of 6 banvel-treated rabbits 15 days post-application. The results suggest that banvel and dicamba are not primary irritants but should nevertheless be employed with caution.
Agnihotri
P K
PK
Murthy
P S
PS
Mukherjee
S K
SK
D000818:Animals; D001565:Benzoates / Q000633:toxicity*; D003996:Dicamba / Q000031:analogs & derivatives / Q000633:toxicity*; D005260:Female; D009092:Mucous Membrane / Q000187:drug effects; D011817:Rabbits; D014621:Vagina / Q000187:drug effects*
D001565:Benzoates; C027233:dicamba dimethylamine; D003996:Dicamba