title: Postoperative results of distal partial gastrectomy, selective vagotomy plus antrectomy, and selective proximal vagotomy for duodenal ulcers.
abstract: We investigated the postoperative results of distal partial gastrectomy, selective vagotomy plus antrectomy, and selective proximal vagotomy, to evaluate their effectiveness in the treatment of duodenal ulcers. The operative mortality of selective vagotomy plus antrectomy and selective proximal vagotomy seemed to be lower when compared to distal partial gastrectomy, although each procedure showed a sufficiently low mortality. The acid reduction rate was significantly lower after selective proximal vagotomy than after the other procedures (p less than 0.01). However, the rate of ulcer recurrence following selective proximal vagotomy tended to be higher compared with the other procedures. All three procedures showed good results according to Visick's grading and postoperative symptoms occurred in about 50 per cent of all patients, no matter what the procedure. The regaining of physical ability was significantly greater following selective proximal vagotomy than following distal partial gastrectomy (p less than 0.05) and the capacity to work was also better after vagotomy, particularly selective vagotomy plus antrectomy (p less than 0.05). Thus, although distal partial gastrectomy and selective vagotomy plus antrectomy proved superior regarding the low ulcer recurrence rate and acid reduction, while selective proximal vagotomy proved superior for improving the quality of life, on the whole, the three operations promise almost equivalent results.
authors.affiliation: Second Department of Surgery, Kumamoto University Medical School, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Misumi
authors.forename: K
authors.initials: K
authors.lastname: Harada
authors.forename: A
authors.initials: A
authors.lastname: Murakami
authors.forename: S
authors.initials: S
authors.lastname: Takano
authors.forename: U
authors.initials: U
authors.lastname: Honmyo
authors.forename: M
authors.initials: M
authors.lastname: Maeda
authors.forename: Y
authors.initials: Y
authors.lastname: Yagi
authors.forename: M
authors.initials: M
authors.lastname: Akagi
mesh_terms: D000328:Adult; D004381:Duodenal Ulcer / Q000503:physiopathology / Q000601:surgery*; D005069:Evaluation Studies as Topic; D005260:Female; D005743:Gastrectomy; D005744:Gastric Acid / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D011706:Pyloric Antrum / Q000601:surgery*; D014628:Vagotomy