title: [Fatal legionellosis in an infant treated with ACTH].
abstract: A new case of fatal systemic legionnaires' disease is reported in an infant. This 8 month-old boy was given a protracted treatment with adrenocorticotropic hormones for infantile spasms. Legionella pneumophila type I was found in tracheal secretions and there was multivisceral involvement at autopsy. The mode of contamination and the severity of the disease are discussed in the light of the immunosuppressive properties of the glucocorticoids administered over a period of 4 weeks.
authors.affiliation: Unité de Réanimation Pédiatrique, Hôpital Pontchaillou, Rennes.
authors.forename: C
authors.initials: C
authors.lastname: Lefrançois
authors.forename: I
authors.initials: I
authors.lastname: Casadevall
authors.forename: P
authors.initials: P
authors.lastname: Betremieux
authors.forename: P Y
authors.initials: PY
authors.lastname: Donnio
authors.forename: H
authors.initials: H
authors.lastname: Jouan
authors.forename: N
authors.initials: N
authors.lastname: Laisney
authors.forename: B
authors.initials: B
authors.lastname: Le Marec
mesh_terms: D003366:Cosyntropin / Q000009:adverse effects / Q000627:therapeutic use; D005602:France / Q000453:epidemiology; D005938:Glucocorticoids / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D007877:Legionnaires' Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D008297:Male; D011379:Prognosis; D013036:Spasms, Infantile / Q000188:drug therapy
chemical_list: D005938:Glucocorticoids; D003366:Cosyntropin
vernacular_title: Légionellose mortelle chez un nourrisson traité par ACTH.