[Long-term effects of treatment with SMS 201-995 on sleep apnea syndrome associated with acromegaly].
A 60-year-old woman with acromegaly associated with sleep apnea was treated with the somatostatin analogue SMS 201-995 (Sandoz) for several months. Growth hormone levels were normalized and a rapid improvement in sleep apnea was controlled with polygraphic nocturnal monitoring. Hypophysectomy seems to have variable effects on sleep apnea in acromegaly. The origin of obstructive apnea in acromegaly is therefore unclear.
Esnault
S
S
Service d'explorations fonctionnelles neurologiques, CHRU, hôpital Morvan, Brest, France.
Merceur
C
C
Kerlan
V
V
Tea
S H
SH
le Mevel
J C
JC
Bercovici
J P
JP
Mabin
D
D
D000172:Acromegaly / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged; D015282:Octreotide / Q000627:therapeutic use*; D012891:Sleep Apnea Syndromes / Q000150:complications / Q000188:drug therapy*; D013997:Time Factors
D015282:Octreotide
Effets à long terme du traitement par SMS 201-995 sur un syndrome d'apnées du sommeil associé à une acromégalie.