Age and membrane fluidity.
Male rats aged 1, 9 and 19 months were used to study changes in membrane fluidity with age, employing the fluorescence polarization technique with 1,6-diphenyl-1,3,5-hexatriene (DPH) as the fluorescent probe. The intestinal microvillus membranes derived from the 19-month-old rats were found to possess lower fluidity than that observed with the membranes derived from the younger animals. The decrease in fluidity with age was also reflected in a corresponding increase in the gel-to-liquid crystalline transition temperature. Only small insignificant changes with age, were observed in the fluidity of the red blood cell membrane.
Wahnon
R
R
Department of Food Engineering and Biotechnology, Technion-Israel Institute of Technology, Haifa.
Mokady
S
S
Cogan
U
U
D000375:Aging / Q000502:physiology*; D000818:Animals; D002462:Cell Membrane / Q000502:physiology; D004910:Erythrocyte Membrane / Q000502:physiology; D007413:Intestinal Mucosa / Q000502:physiology; D008297:Male; D008560:Membrane Fluidity; D051381:Rats