title: [An empirical correlation between optical rotation and absolute configuration of optically active alpha-methylbutyrylphloroglucinols and its synthesis].
abstract: Fourteen new compounds were synthesized of which twelve are (S)-(+)-alpha-methylbutyrylphloroglucinols. On the basis of optical rotation data and theoretical analysis, an empirical correlation between optical rotation and absolute configuration of optically active alpha-methylbutyrylphloroglucinols has been established by means of Brewster's rule of atomic asymmetry. It can be served as a means of absolute configuration assignment of optically active alpha-methylbutyrylphloroglucinols.
authors.forename: Y H
authors.initials: YH
authors.lastname: Pei
authors.forename: X
authors.initials: X
authors.lastname: Li
authors.forename: T R
authors.initials: TR
authors.lastname: Zhu
mesh_terms: D008968:Molecular Conformation; D009904:Optical Rotation; D010696:Phloroglucinol; D013237:Stereoisomerism
chemical_list: D010696:Phloroglucinol