[Fibronectin levels in the blood and cerebrospinal fluid in cerebrovascular diseases].
A total of 106 patients with different forms of cerebral circulation disorders and 28 healthy donors were investigated for the contents of fibronectin and its proteolytic degradation products in the blood and cerebrospinal fluid. In patients with cerebrovascular disorders the decrease in the blood fibronectin levels was accompanied by a decrease in its metabolite levels and increased R-protein content, irrespective of the character and degree of clinical manifestations. The fibronectin CSF levels were increased in acute stroke with unconsistent rise in R-proteins. The authors suggest that fibronectin synthesis and degradation are evidently controlled by R-proteins being the products of destruction of cellular receptors.
Bakunts
G O
GO
Ku'lberg
A Ia
AIa
Oganian
R R
RR
Seliksetian
M S
MS
Gabrielian
M S
MS
D000328:Adult; D000368:Aged; D002545:Brain Ischemia / Q000378:metabolism; D002543:Cerebral Hemorrhage / Q000378:metabolism; D002544:Cerebral Infarction / Q000378:metabolism; D002561:Cerebrovascular Disorders / Q000097:blood / Q000134:cerebrospinal fluid / Q000378:metabolism*; D005353:Fibronectins / Q000097:blood / Q000134:cerebrospinal fluid / Q000378:metabolism*; D006801:Humans; D008875:Middle Aged
D005353:Fibronectins
Soderzhanie fibronektina v krovi i spinnomozgovoĭ zhidkosti pri narusheniiakh mozgovogo krovoobrashcheniia.