[Pharmacokinetics of tetrachloroethylene in steady stage conditions].
Pharmacokinetic behaviour of tetrachloroethylene (clearance, pool, elimination kinetics, metabolic capacity) was studied by intravenous and inhalative long term administration. Concentrations of tetrachloroethylene in blood can be calculated from the concentration in the external air, as to be predicted for a substance, practically not metabolizable and eliminated totally by exhalation. The advantages of steady state techniques and their applicability to problems of industrial pharmacology are discussed.
Müller
C
C
Fleischer
C
C
Fahnert
R
R
D000280:Administration, Inhalation; D000818:Animals; D007262:Infusions, Intravenous; D008657:Metabolic Clearance Rate; D011817:Rabbits; D013750:Tetrachloroethylene / Q000008:administration & dosage / Q000493:pharmacokinetics*
D013750:Tetrachloroethylene
Pharmakokinetik von Tetrachlorethen unter Steady-state-Bedingungen.