title: [Evaluation of 2 modalities of use of propofol in cerebral angiography].
abstract: Fifty eight adult patients suffering from different intracranial lesions and scheduled for cerebral angiography were given propofol. In the first group (38 patients) brief periods of anaesthesia were induced and reinduced by means of 1.5 mg/kg of propofol iv and sometimes extended with boluses of 25-50 mg of this anesthetic. The patients were premedicated with 0.5 mg atropine im 30-40 min before the induction. Fentanyl, droperidol and diazepam in various combinations and doses were injected, im together with the atropine and iv 1-2 min before the induction, to obtain long-lasting sedations. In the second group (20 patients) the induction of the anaesthesia started 20-35 min after 0.5 mg of atropine im and 1 min after 0.1 mg of fentanyl iv. The induction was based on a bolus of 2.5 mg/kg of propofol and it was followed by suxamethonium, tracheal intubation and mechanical ventilation with N2O 70% in O2. An adequate depth of anaesthesia was maintained with supplemental doses of 50 mg of propofol, frequently associated with 25 mg of suxamethonium. Both methods proved to be reliable and safe. Nevertheless, the second method provided a better stability as far as a number of physiologic variables is concerned.
authors.forename: A
authors.initials: A
authors.lastname: Rossi
authors.forename: C
authors.initials: C
authors.lastname: Siani
authors.forename: J
authors.initials: J
authors.lastname: Zattoni
authors.forename: G
authors.initials: G
authors.lastname: Guiducci
authors.forename: T
authors.initials: T
authors.lastname: Capuzzo
authors.forename: G
authors.initials: G
authors.lastname: Ardizzone
mesh_terms: D000328:Adult; D000368:Aged; D000768:Anesthesia, General / Q000379:methods*; D002533:Cerebral Angiography / Q000187:drug effects*; D005069:Evaluation Studies as Topic; D006801:Humans; D007275:Injections, Intravenous; D008875:Middle Aged; D015742:Propofol / Q000008:administration & dosage*
chemical_list: D015742:Propofol
vernacular_title: Valutazione di due modalità di impiego del propofol nelle angiografie cerebrali.