Platelet norepinephrine and serotonin balance in migraine.
Platelet serotonin (5 hydroxytryptamine, 5-HT) and norepinephrine (NE) were measured in common and classic migraine patients and healthy controls. Common migraine sufferers had high NE levels and a low 5-HT/NE ratio. Classic migraine patients had a high 5-HT level and a high 5-HT/NE ratio. The data suggest disparate NE and 5-HT metabolism between common and classic migraine.
D'Andrea
G
G
Welch
K M
KM
Grunfeld
S
S
Joseph
R
R
Nagel-Leiby
S
S
D000293:Adolescent; D000328:Adult; D001792:Blood Platelets / Q000378:metabolism*; D005260:Female; D006801:Humans; D008875:Middle Aged; D008881:Migraine Disorders / Q000097:blood*; D009638:Norepinephrine / Q000097:blood*; D012701:Serotonin / Q000097:blood*
D012701:Serotonin; D009638:Norepinephrine