title: Effects of ivermectin on control of gastrointestinal nematodes and weight gain in weaner-yearling beef cattle.
abstract: Four groups of 16 crossbred beef calves were used in evaluating different anthelmintic treatment schedules: group 1 was given ivermectin (IVM) at weaning only (October 31) and grazed on initially safe pasture; group 2 was given IVM at weaning, on January 28, and on April 22, and grazed on contaminated pasture; and group 3 was given IVM at weaning and on April 22, and grazed on contaminated pasture; and group-4 was group treated with fenbendazole (FBZ) at weaning only, with provision for individual salvage treatment, and grazed on contaminated pasture. The investigation was from Oct 31, 1984, to Oct 9, 1985. Initially high fecal egg counts at weaning were more effectively reduced by IVM than by FBZ, and the effect of safe pasture was evident in minimal worm burdens in tracer calves grazed with group-1 cattle during November and least amount of weight loss in group-1 yearlings during winter. Fecal egg counts, pasture larval counts, and plasma pepsinogen concentrations remained low in group 2 after the January treatment. Fecal egg counts of the other groups increased substantially during late winter and spring, but pasture larval counts increased only on group-1 and group-4 pastures. During spring, highest worm burdens were found in group-1 and group-4 tracer calves (grazed in April) and in group-3 and group-4 yearlings (slaughtered in early April). Six cattle of group 4 were salvage treated with FBZ in February and April. Greatest gains were observed from March through June, with group-2 and group-1 cattle gaining the most.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Veterinary Science, Louisiana State University Agricultural Center, Baton Rouge 70803.
authors.forename: J C
authors.initials: JC
authors.lastname: Williams
authors.forename: J W
authors.initials: JW
authors.lastname: Knox
authors.forename: K S
authors.initials: KS
authors.lastname: Marbury
authors.forename: M D
authors.initials: MD
authors.lastname: Kimball
authors.forename: R E
authors.initials: RE
authors.lastname: Willis
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy / Q000517:prevention & control*; D006189:Haemonchus / Q000187:drug effects; D007559:Ivermectin / Q000627:therapeutic use*; D008297:Male; D009348:Nematoda / Q000187:drug effects*; D009349:Nematode Infections / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary*; D010028:Ostertagia / Q000187:drug effects; D014254:Trichostrongylus / Q000187:drug effects; D015430:Weight Gain
chemical_list: D007559:Ivermectin