[Neonatal varicella: indications for the use of varicella-zoster specific immunoglobulin].
Case reports from January-1986 through December-1988 of neonates born to women who develop varicella and neonates with household postnatal exposure are presented. Mother developed varicella in three cases (15 days before delivery, at delivery, 10 days after delivery), the last case was infected by direct exposure from his brothers. Only neonates with household contacts developed varicella. In every case varicella-zoster immunoglobulin a doses of 0.2 mg/kg/day from the three days was administered. Adding aciclovir intravenous a daily doses of 15 mg/kg/8h for seven days in neonates who developed varicella. Are propose considered a high risk group the neonates with postnatal exposure.
Espino Aguilar
R
R
Departamento de Pediatría, Hospital Regional Reina Sofía, Córdoba.
de la Torre Cecilia
M C
MC
Huertas Muñoz
M D
MD
Guzmán Cabañas
J
J
Fernández Gutiérrez
F
F
Zapatero Martínez
M
M
Romanos Lezcano
A
A
D000212:Acyclovir / Q000627:therapeutic use*; D002644:Chickenpox / Q000188:drug therapy / Q000628:therapy* / Q000635:transmission; D005260:Female; D005315:Fetal Diseases / Q000628:therapy*; D006801:Humans; D007106:Immune Sera; D007116:Immunization, Passive; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D012307:Risk Factors
D007106:Immune Sera; C030799:varicella-zoster immune globulin; D000212:Acyclovir
Varicela neonatal: indicaciones para el uso de inmunoglobulina específica varicela-zoster.