Breathing pattern of spontaneously hypertensive rats.
The trachea of rats anaesthetized with sodium pentobarbitone was cannulated and the air flow velocity and the pressure of the oesophagus were measured. In the spontaneously hypertensive rats the breathing frequency was higher, the tidal volume and the effective lung resistance were smaller than that of the normotensive Wistar rats. It seems that the neurohumoral control of respiration in SHR animals differs from that of normotensive rats.
Debreczeni
L A
LA
Experimental Pathophysiological Research Unit, National Korányi Institute for TBC and Pulmonology, Budapest, Hungary.
Vértes
K
K
Barát
E
E
Huszár
E
E
D000818:Animals; D006973:Hypertension / Q000503:physiopathology*; D008168:Lung / Q000294:innervation / Q000503:physiopathology*; D051381:Rats; D011918:Rats, Inbred SHR; D011919:Rats, Inbred Strains; D012119:Respiration; D012129:Respiratory Function Tests; D013564:Sympathetic Nervous System / Q000503:physiopathology