title: No reduction of high density lipoprotein2 during weight reduction in obese children and adolescents.
abstract: The effects of a 3 week weight reduction regimen on lipids and lipoproteins, in particular high density lipoprotein (HDL)-subfractions in 61 grossly obese children and adolescents (37 females and 26 males) aged 11-15 years were studied. Dietary treatment resulted in a significant weight reduction of initial body weight of 9.6 +/- 2.1%, a highly significant decrease in cholesterol, low density lipoprotein cholesterol (LDL-C) and HDL-C (P less than 0.001), as well as a significant reduction in triglycerides, HDL3 and Apolipoprotein B concentrations (P less than 0.01). HDL2 concentrations remained almost constant. It is concluded that HDL reduction during a weight reducing regimen in adolescents does not result in a decrease of the antiatherogenic HDL2 subfraction.
authors.affiliation: Department of Paediatrics, University of Vienna, Austria.
authors.forename: K
authors.initials: K
authors.lastname: Zwiauer
authors.forename: B
authors.initials: B
authors.lastname: Kerbl
authors.forename: K
authors.initials: K
authors.lastname: Widhalm
mesh_terms: D000293:Adolescent; D001053:Apolipoproteins / Q000097:blood; D002648:Child; D002784:Cholesterol / Q000097:blood; D004038:Diet, Reducing; D005260:Female; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood*; D008297:Male; D009765:Obesity / Q000097:blood* / Q000178:diet therapy; D014280:Triglycerides / Q000097:blood
chemical_list: D001053:Apolipoproteins; D008075:Lipoproteins, HDL; D014280:Triglycerides; D002784:Cholesterol