[The effect of para-aminomethylbenzoic acid (amben) on peripheral nerve regeneration].
Various injuries to the sciatic nerve were modelled in experiments on 60 rats and 27 dogs to study the effect of paraaminomethylbenzoic acid on its regeneration; the efficacy of amben was compared with that of other agents used widely for the treatment of injuries to nerves. It was found that amben acts on the connective tissue of the neural scar and creates favourable conditions for growth of axons from the central to the peripheral stump of the injured nerve and accelerated their maturation.
Chaĭkovskiĭ
Iu B
IuB
Voĭtenko
G N
GN
Dobrobol'skiĭ
Iu N
IuN
Diordiĭchuk
V V
VV
D010129:4-Aminobenzoic Acid / Q000494:pharmacology; D000200:Action Potentials / Q000187:drug effects / Q000502:physiology; D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D008866:Microsurgery; D009412:Nerve Fibers / Q000187:drug effects / Q000502:physiology; D009416:Nerve Regeneration / Q000187:drug effects*; D051381:Rats; D012584:Sciatic Nerve / Q000187:drug effects / Q000293:injuries / Q000502:physiology*; D013997:Time Factors; D062366:para-Aminobenzoates
D062366:para-Aminobenzoates; C015668:4-aminomethylbenzoic acid; D010129:4-Aminobenzoic Acid
Vliianie paraaminometilbenzoĭnoĭ kisloty (ambena) na regeneratsiiu perifericheskogo nerva.