[Changes in cells of the adenohypophysis after its simultaneous implantation with various hypothalamic nuclei].
In 55 mature male rabbits and in 65 hypophysis-ectomized inbred male rats (body mass 200-230 g) implantation of the adenohypophysis with supraoptic, paraventricular and arcuate hypothalamic nuclei into the anterior chamber of the eye has been performed. The adenohypophyseal cellular structure has been estimated by means of light and electron microscopy from 12 up to 26 days of implantation. At a direct influence to the implanted adenocytes of the hypophysis substances of the supraoptic and paraventricular nuclei ensure stimulation of their proliferative processes, accompanied with increase of DNA synthesis. Besides, secretory process enhances in some somato-, mammo- and thyreotropocytes. Discovery of such cells as thyreo-, mammo- and corticotropocytes in newly-formed epithelial proliferates is considered as a fact of their possible functional differentiation de novo. Implantation of the adenohypophysis with the arcuate hypothalamic nuclei reveals activation in folliculin stimulating hormone in gonadotropocytes. During the process of secondary differentiation this group of adenocytes makes the greatest part of the cells. Somato-, mammotropocytes inhibit cytodifferentiation.
Stadnikov
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D000818:Animals; D000867:Anterior Chamber / Q000601:surgery*; D001111:Arcuate Nucleus of Hypothalamus / Q000166:cytology*; D002452:Cell Count; D002454:Cell Differentiation / Q000502:physiology; D007016:Hypophysectomy; D008297:Male; D008938:Mitosis / Q000502:physiology; D010286:Paraventricular Hypothalamic Nucleus / Q000166:cytology*; D010902:Pituitary Gland / Q000637:transplantation*; D010903:Pituitary Gland, Anterior / Q000166:cytology*; D011817:Rabbits; D051381:Rats; D013495:Supraoptic Nucleus / Q000166:cytology*; D016042:Transplantation, Heterotopic / Q000379:methods
Izmeneniia kletok adenogipofiza pri sovmestnoĭ implantatsii s razlichnymi iadrami gipotalamusa.