Hypersensitivity to trichophytin in small animals experimentally infected with Trichophyton equinum.
Typical lesions resulting from experimental Trichophyton equinum infection in laboratory animals persisted for 3-4 weeks. Lesions in rabbits were slightly less severe than those in guinea pigs. In experimentally infected dogs lesions persisted for longer and developed in the form of a deep, crusty dermatophytosis. In skin tests with three trichophytins it was shown that specific hypersensitivity resulting from infection of laboratory animals persists for at least 6 months. Stronger local reactions were produced with homologous trichophytins, especially in the final tests after 6 months.
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Clinic for Infectious Diseases of Animals, Veterinary Faculty, Agricultural Academy, Lublin, Poland.
D000818:Animals; D000946:Antigens, Fungal / Q000276:immunology*; D004285:Dogs; D005260:Female; D006168:Guinea Pigs; D006736:Horses; D006967:Hypersensitivity / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D007428:Intradermal Tests / Q000662:veterinary; D008297:Male; D011817:Rabbits; D014005:Tinea / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D014248:Trichophytin / Q000276:immunology*; D014249:Trichophyton / Q000472:pathogenicity*; D014774:Virulence
D000946:Antigens, Fungal; D014248:Trichophytin