title: Preventing and alleviating hypothermia-induced amnesia in weanling and young adult rats.
abstract: Reminder (Experiment 1) and familiarization (Experiment 2) treatments were found to have similar effects on the 24-hr retention performance of 24- to 26- and 90- to 100-day-old rats that either did or did not undergo an amnesic treatment (hypothermia) immediately after training. Similar degrees of retrograde amnesia and normal forgetting were evident in both trained age groups that were not subjected to familiarization or reminder treatments. These results suggest that memory processes in weanling and adult rats are similar in susceptibility to disruption by an established amnesic treatment (hypothermia) and in the ease of prevention of and recovery from amnesia by recognized preventive (familiarization) and alleviation (reminder) measures. The similarity of the effects of these preventive and alleviation treatments on normal forgetting and induced amnesia suggests that experimentally induced amnesia may be a fruitful approach to studying the ontogeny of memory processes and, more specifically, to studying factors that influence infantile amnesia.
authors.affiliation: Psychology Department, University of Pittsburgh, Johnstown 15904.
authors.forename: C F
authors.initials: CF
authors.lastname: Hinderliter
authors.forename: P
authors.initials: P
authors.lastname: Blanton
authors.forename: J R
authors.initials: JR
authors.lastname: Misanin
mesh_terms: D000375:Aging / Q000523:psychology*; D000818:Animals; D001143:Arousal; D001362:Avoidance Learning; D001833:Body Temperature Regulation; D005260:Female; D008297:Male; D008568:Memory; D011939:Mental Recall; D051381:Rats; D011919:Rats, Inbred Strains; D011930:Reaction Time; D012153:Retention, Psychology; D014886:Weaning