title: Disturbed endocrine function in the psychoses. II: Discriminant function analysis of multihormone data.
abstract: Discriminant function analyses were performed on plasma concentrations of prolactin, growth hormone, cortisol, TSH, and the neurophysins measured over 17 hours in 70 newly admitted drug-free psychiatric patients and 35 control subjects. The hormone data distinguished between patients with different classes of drug-free psychosis (26 schizophrenic, 12 with manic disorder, 10 with major depressive disorder, psychotic subtype, 9 with schizoaffective mania (SAM]. Higher plasma cortisol and lower TSH concentrations separated eight of nine SAM patients from all others.
authors.affiliation: Edinburgh University, Department of Psychiatry.
authors.forename: L J
authors.initials: LJ
authors.lastname: Whalley
authors.forename: J E
authors.initials: JE
authors.lastname: Christie
authors.forename: D H
authors.initials: DH
authors.lastname: Blackwood
authors.forename: J
authors.initials: J
authors.lastname: Bennie
authors.forename: H
authors.initials: H
authors.lastname: Dick
authors.forename: I M
authors.initials: IM
authors.lastname: Blackburn
authors.forename: G
authors.initials: G
authors.lastname: Fink
mesh_terms: D001714:Bipolar Disorder / Q000097:blood; D003866:Depressive Disorder / Q000097:blood; D016002:Discriminant Analysis; D005260:Female; D006728:Hormones / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D009481:Neurophysins / Q000097:blood; D011388:Prolactin / Q000097:blood; D011618:Psychotic Disorders / Q000097:blood* / Q000175:diagnosis; D012559:Schizophrenia / Q000097:blood; D013972:Thyrotropin / Q000097:blood
chemical_list: D006728:Hormones; D009481:Neurophysins; D011388:Prolactin; D013972:Thyrotropin; D006854:Hydrocortisone