title: Effect of aerobic exercise on mouth-to-cecum transit time.
abstract: To examine the premise that exercise reduces the gastrointestinal transit time, we evaluated the effect of walking 4.5 km in an hour on mouth-to-cecum transit time. Twenty-three healthy volunteers, 9 men and 14 women, with an age range of 19-28 yr, were studied. After an overnight fast, the subjects ingested 10 g of lactulose in 150 ml of water while breath hydrogen concentrations were analyzed at 15-min intervals. On separate days, in random sequence, subjects either sat in a chair or walked on a treadmill for 60 min. Mean transit time was 55 +/- 8 min when resting and 89 +/- 4 min when exercising (p less than 0.001). In conclusion, light aerobic exercise prolonged the mouth-to-cecum transit time. On the basis of this observation, exercise as a causative factor in runner's diarrhea and its value in the management of chronic constipation may be questioned.
authors.affiliation: Department of Medicine, University of California, Irvine.
authors.forename: H
authors.initials: H
authors.lastname: Meshkinpour
authors.forename: C
authors.initials: C
authors.lastname: Kemp
authors.forename: R
authors.initials: R
authors.lastname: Fairshter
mesh_terms: D000328:Adult; D001944:Breath Tests; D015444:Exercise; D005260:Female; D005772:Gastrointestinal Transit; D006801:Humans; D006859:Hydrogen / Q000032:analysis; D007792:Lactulose; D008297:Male
chemical_list: D007792:Lactulose; D006859:Hydrogen