title: Quinolizidine derivatives as potential antitumoral agents.
abstract: The activity against lymphocytic leukemia P 388 has been evaluated for thirteen compounds bearing a quinolizidine moiety bound respectively to a phenothiazine nucleus or other isosteric tricyclic systems (12-17), as well to a quinoxalinone (18-20) or an indole (21-24) nucleus. All tested compounds resulted inactive.
authors.affiliation: Istituto di Chimica Biologica, Università di Genova.
authors.forename: A
authors.initials: A
authors.lastname: Sparatore
authors.forename: C
authors.initials: C
authors.lastname: Boido Canu
authors.forename: V
authors.initials: V
authors.lastname: Boido
authors.forename: F
authors.initials: F
authors.lastname: Sparatore
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D007941:Leukemia P388 / Q000188:drug therapy; D051379:Mice; D008815:Mice, Inbred Strains; D011807:Quinolizines / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D011807:Quinolizines