title: Lysosomal membrane stabilization by antiinflammatory drugs.
abstract: Lysosomal enzymes are important mediators of acute and chronic inflammatory diseases. The release of lysosomal enzymes into cytoplasm stimulate the inflammatory mediators like oxygen radicals, prostaglandins etc. Enfenamic acid, a fenamate, along with other antiinflammatory drugs, did not stabilize lysosomal membrane isolated from normal and activated phagocytic polymorphonuclear leucocytes of different species.
authors.forename: A B
authors.initials: AB
authors.lastname: Rao
authors.forename: P
authors.initials: P
authors.lastname: Sisodia
authors.forename: P B
authors.initials: PB
authors.lastname: Sattur
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D006168:Guinea Pigs; D066298:In Vitro Techniques; D008247:Lysosomes / Q000187:drug effects*; D009504:Neutrophils / Q000187:drug effects
chemical_list: D000893:Anti-Inflammatory Agents