[Clinical effects of cefodizime against infectious diseases in obstetrics and gynecology].
Clinical studies on cefodizime (CDZM) were performed in patients of obstetrics and gynecology. CDZM was given to patients via drip infusion at a daily dose of 2-4 g, and the results obtained are summarized as follows: 1. A total of 10 cases included 5 cases of intrauterine infections (3 cases of puerperal endometritis, 1 endometritis and 1 puerperal fever), 2 intrapelvic infections (1 pelvic dead space infection and 1 parametritis), and 3 Bartholin's abscess. Clinical efficacies were excellent in 3 cases, good in 6 and poor in 1. The efficacy rate was 90% (9/10). 2. Bacteriological efficacies were as follows: eradicated in 3 cases, replaced in 2, decreased in 1, persisted in 1 and unknown in 3. 3. Neither subjective and objective adverse reactions nor abnormal changes in laboratory test values were observed.
Chimura
T
T
Department of Obstetrics and Gynecology, School of Medicine, Yamagata University.
Morisaki
N
N
Hirayama
T
T
Matsuo
M
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D001398:Aztreonam / Q000008:administration & dosage; D001419:Bacteria / Q000302:isolation & purification; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D002439:Cefotaxime / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002981:Clindamycin / Q000008:administration & dosage; D004341:Drug Evaluation; D005260:Female; D005831:Genital Diseases, Female / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D007262:Infusions, Intravenous; D008875:Middle Aged
D002981:Clindamycin; D001398:Aztreonam; D002439:Cefotaxime; C033356:cefodizime