Combined heart and kidney transplantation using the same donor.
A 45-year-old man received a combined heart and kidney transplant provided by the same donor. The patient was in the terminal stage of renal failure and was submitted to 3 sessions of haemodialysis per week for 2 years before transplantation. A dilated cardiomyopathy with severe impairment of left ventricular (LV) function was discovered, precluding renal transplantation alone. In the postoperative course, a cardiac rejection episode was detected by echocardiography and documented by endomyocardial biopsy; no simultaneous rejection of the kidney could be detected. The patient was discharged after 2 months, and he resumed a normal and active life. The specific problems raised by the management of such multi-organ transplantation are briefly reviewed.
Cachera
J P
JP
Department of Thoracic and Cardiovascular Surger, Hospital Henry-Mondor, Creteil, France.
Abbou
C
C
Deleuze
P
P
Hillion
M L
ML
Loisance
D
D
Romano
P
P
Laurent
F
F
Touzani
A
A
Tavolaro
O
O
Hittenger
L
L
D002311:Cardiomyopathy, Dilated / Q000601:surgery; D006084:Graft Rejection; D016027:Heart Transplantation / Q000473:pathology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology; D014019:Tissue Donors