title: Effects of aging on mucociliary clearance.
abstract: Preliminary results from the relationship between aging and mucociliary clearance of inhaled 99-Tc human albumin particles (0.92-2.5 microns) are reported from two groups of healthy non-smokers: 1) 20-61-year-old (mean 42 years) and 2) 71-90-year-old (mean 79.5 years). The analytical procedure is presented, and on the basis of the analysis it is concluded that there is evidence for an age-related decline of the mucociliary clearance by a bi-phasic curve, similar to those reported in the literature for other physiological functions.
authors.affiliation: Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: R A
authors.initials: RA
authors.lastname: Incalzi
authors.forename: C L
authors.initials: CL
authors.lastname: Maini
authors.forename: L
authors.initials: L
authors.lastname: Fuso
authors.forename: A
authors.initials: A
authors.lastname: Giordano
authors.forename: P U
authors.initials: PU
authors.lastname: Carbonin
authors.forename: G
authors.initials: G
authors.lastname: Galli
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D005260:Female; D006801:Humans; D008168:Lung / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009079:Mucociliary Clearance / Q000502:physiology*