First observation of haemoglobin Malay alpha 2B2 26 (B1) Asn----Ser--a case report.
A new haemoglobin, Haemoglobin Malay is described in a 22 year old Malay. Structural analysis showed a AAC----AGC mutation in codon 17, with the production of an abnormal beta chain (beta Malay) that has an Asn----Ser substitution at position beta 19. This haemoglobin variant could not be detected by conventional procedures.
George
E
E
Huisman
T H
TH
Yang
K G
KG
Kutlari
F
F
Wilson
J B
JB
Kutlar
A
A
Storming
T A
TA
Gonzales-Redondo
J M
JM
Faridah
K
K
Khalid
A K
AK
D000328:Adult; D004252:DNA Mutational Analysis; D005914:Globins; D006455:Hemoglobins, Abnormal; D006801:Humans; D008296:Malaysia; D008297:Male; D010375:Pedigree
D006455:Hemoglobins, Abnormal; C063216:hemoglobin Malay; D005914:Globins