title: [Progressive systemic sclerosis, B-cell malignant lymphoma of the ileum and thyroid adenocarcinoma].
abstract: A patient with progressive systemic sclerosis with rapid evolution to death is presented. The post-morten examination revealed besides the typical changes of the progressive systemic sclerosis in the skin, kidneys, heart and blood vessels a B-cell ileal malignant lymphoma with generalized metastases, and an adenocarcinoma of the thyroid gland. A possible mechanism involved in the association of these diseases might be the action of the oncogenes modifying the cellular hormostasis and the immunological tolerance.
authors.forename: C J
authors.initials: CJ
authors.lastname: Rodrigues
authors.forename: H
authors.initials: H
authors.lastname: Bisi
authors.forename: N
authors.initials: N
authors.lastname: Yoshinari
authors.forename: P E
authors.initials: PE
authors.lastname: Marchiori
authors.forename: W
authors.initials: W
authors.lastname: Cossermelli
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology; D000328:Adult; D005260:Female; D006801:Humans; D007078:Ileal Neoplasms / Q000150:complications* / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000473:pathology; D012595:Scleroderma, Systemic / Q000150:complications* / Q000473:pathology; D013964:Thyroid Neoplasms / Q000150:complications* / Q000473:pathology
vernacular_title: Esclerose sistêmica progressiva, linfoma maligno de células B em íleo e adenocarcinoma de tireóide.