[Amyloidosis lesions of the digestive organs in patients with tuberculosis and chronic nonspecific lung diseases].
Histological postmortem examination of 30 persons who had died of pulmonary tuberculosis complicated by renal amyloidosis revealed amyloid affections in the rectum, stomach and liver of 76.3, 60 and 56.7 per cent of the dead, respectively. Histological examination of biopsy specimens of the gastric and duodenal mucosa from 20 patients with pulmonary tuberculosis revealed amyloid affections in 17 of them (85 per cent). An analogous examination of 18 patients with chronic nonspecific diseases of the lungs revealed amyloidosis of the organs in 10 persons (55.6 per cent). Efficiency of using proteinase inhibitors such as amben, epsilon-aminocapronic acid and contrical in the prevention and treatment of secondary amyloidosis of the digestive organs was studied experimentally.
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D000328:Adult; D000686:Amyloidosis / Q000209:etiology* / Q000473:pathology / Q000517:prevention & control; D000818:Animals; D001706:Biopsy; D002908:Chronic Disease; D004064:Digestive System / Q000473:pathology; D004066:Digestive System Diseases / Q000209:etiology* / Q000473:pathology / Q000517:prevention & control; D004353:Drug Evaluation, Preclinical; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D008171:Lung Diseases / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011480:Protease Inhibitors / Q000627:therapeutic use; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
D011480:Protease Inhibitors
Porazhenie amiloidozom organov pishchevareniia u bol'nykh tuberkulezom i khronicheskimi nespetsificheskimi zabolevaniiami legkikh.