[The clinico-laboratory characteristics of the cholestatic form of acute alcoholic hepatitis].
The study includes 108 patients with acute alcohol hepatitis, 45 patients with cholestasis and 124 healthy controls. In 14 patients (13%) cholestatic acute alcohol hepatitis was found. The patients with cholestatic acute alcohol hepatitis consumed considerably more alcohol than the other patients with acute alcohol hepatitis. The intensive jaundice led half of the patients with cholestatic acute alcohol hepatitis to the infectious diseases clinic and 32% of them to the surgical clinic. The course of the disease was heavy, with disturbed general condition, high temperature, pain in the right subcostal region but without itching. The patients showed higher levels of timol test, cholesterol, LDL-cholesterol, coefficient LDL/HDL-cholesterol, beta-lipoproteins, total lipids, gamma-GTP, ASAT and lower levels of leucocytes, bilirubin, SMC, alkaline phosphatase and LAP than the other patients with cholestasis. The patients with cholestatic acute alcohol hepatitis showed a higher level of total lipids and gamma-GTP than the other patients examined. The confirmation of the diagnosis implies the application of contemporary instrumental and invasive methods. The ultrasound examination is of special importance.
Vŭrbanov
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G
D000208:Acute Disease; D001651:Cholestasis, Extrahepatic / Q000097:blood / Q000175:diagnosis; D002780:Cholestasis, Intrahepatic / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D006519:Hepatitis, Alcoholic / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008875:Middle Aged
Klinikolaboratorni osobenosti na kholestatichnata forma na ostriia alkokholen khepatit.