Psoralene in repigmentation of tuberculoid leprosy.
Photoactivated psoralens were studied in sixty cases of tuberculoid leprosy for the repigmentation of hypopigmented macules. It was observed that in 42 (70%) cases there was significant repigmentation within 6 months of therapy; in 5 (8.33%) cases there was mild to moderate repigmentation and in 13 (22.64%) cases, there was no change. No significant untoward effects of drug were encountered, except in four patients (6.66%), who developed, marked erythema and eczematous reaction.
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D005260:Female; D006801:Humans; D015441:Leprosy, Tuberculoid / Q000150:complications* / Q000188:drug therapy; D008297:Male; D011701:PUVA Therapy / Q000379:methods*; D010859:Pigmentation Disorders / Q000188:drug therapy* / Q000209:etiology; D012737:Sex Factors