[Polyserositic syndromes and/or sectorial dysventilation with platelet activation induced by immunoallergic etiopathogenesis].
The author from a study of 5 dysventilatorial syndromes (bronchiolitis-PNX, pneumomediastinal aerial cystis of lung) and 5 polysierositic syndromes pleuritis and peritonitis) evices that all these syndromes show in the anamnesis or in present a viral infection from influenzal virus or rubeola. In addition to that, the Authors shows the presence of a food allergy asserted by RAST and/or Skin Prick Tests or FBST (Food Bronchostimulation test) and the introduction of a food allergen during the viral infection, and a great platelet's activation. The Author, besides, shows the association normal VES and normal neutrophil cells in the dysventilatorial syndrome and high VES, and high neutrophil cells in the polysierositic syndromes; in all cases the negativity of culture exams. Starting from these points she worked out a new etiopathogenetic theory: the viral localization on the Peyer's plates cause the expression on the epithelial surface of the gut's cells of SELF HLA II type recognition. The food allergens' introduction causes a great reaction of II, III, IV, VI type which involves the bronchus, alveolus, and the serous epithelium by PAF activation, in all cases and in the polisierositic syndrome a neutrophil activation as well. The author advices to prize the importance of cortisone therapy and of exclusion of food allergen by diet, besides advices the antibiotic therapy for covering only.
De Luca
L
L
I. Divisione di Pediatria, Fisiopatologia Respiratoria e Allergologia, Ospedale Santobono, Napoli, Italia.
D000293:Adolescent; D000542:Alveolitis, Extrinsic Allergic / Q000276:immunology; D001988:Bronchiolitis / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D005512:Food Hypersensitivity / Q000150:complications*; D006801:Humans; D007223:Infant; D015539:Platelet Activation; D010996:Pleural Effusion / Q000628:therapy; D010998:Pleurisy / Q000276:immunology*; D011859:Radiography; D012131:Respiratory Insufficiency / Q000000981:diagnostic imaging / Q000276:immunology*; D012700:Serositis / Q000000981:diagnostic imaging / Q000276:immunology*; D013577:Syndrome
Sindromi polisierositiche e/o disventilatorie settoriali con attivazione piastrinica da etiopatogenesi immunoallergica.