The prognostic value of a prior spermatozoa study for human in vitro fertilization.
Patients admitted for treatment of in vitro fertilization (IVF) were subjected to a semen investigation about 1-2 weeks prior to actual IVF and again during IVF. In addition to routine semen analyses, the recovery efficiency of motile spermatozoa by swim-up technique and Percoll gradient separation, the level of semen lactate dehydrogenase and the viability of the spermatozoa in the insemination medium were also studied. There is a significant correlation between the results of the pre-IVF analyses and that observed during IVF suggesting that a prior investigation of semen profile and sperm function is useful to screen potential IVF candidates. Among the various parameters, sperm motility in the semen and the swim-up preparation, percent normal spermatozoa and in vitro viability were significantly related to the outcome of IVF.
Tam
P P
PP
Loong
E P
EP
Chan
C
C
Chiu
T
T
Hui
N
N
D005307:Fertilization in Vitro; D006801:Humans; D007248:Infertility, Male / Q000175:diagnosis*; D007317:Insemination, Artificial, Homologous; D008297:Male; D011379:Prognosis; D013094:Spermatozoa / Q000502:physiology*