[Pulmonary toxicity of amiodarone].
A case of lung disease due to amiodarone is described based on epidemiological, clinical and evolution criteria, bronchoalveolar lavage (BAL) analysis, X-ray and pathological study by optic and electron microscopy. Iodine on pulmonary tissue quantified spectrophotometrically was 2 p.p.m. This was not observed in normal lung tissue. The best diagnostic criteria for amiodarone pneumopathy are discussed highlighting lymphocytosis in the BAL and the presence of dense lamellar bodies in the ultrastructural study of the affected lung tissue.
Sevillano Martín
C
C
Callol Sánchez
L
L
Calderón Alvarez
J
J
Moreno Muro
M
M
Gómez de Terreros
F J
FJ
D000368:Aged; D000638:Amiodarone / Q000009:adverse effects*; D001992:Bronchoalveolar Lavage Fluid / Q000473:pathology; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D011658:Pulmonary Fibrosis / Q000139:chemically induced* / Q000473:pathology
D000638:Amiodarone
Toxicidad pulmonar por amiodarona.