title: Electrostatic interaction in the reaction between porphyrin and DNA.
abstract: The association of tetrakis(4-N-methylpyridyl)porphine with salmon testes DNA in solution has been investigated in the presence of ethanol at 25 degrees C. It was found that the association constant was 1.14 x 10(6) M-1 and it increased with increasing the mole fraction of added ethanol. The behavior was very different from that in the case of usual intercalaters.
authors.affiliation: Department of Chemistry, Faculty of Science, Konan University, Kobe, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Sugimoto
authors.forename: K
authors.initials: K
authors.lastname: Hasegawa
authors.forename: N
authors.initials: N
authors.lastname: Monden
authors.forename: M
authors.initials: M
authors.lastname: Sasaki
mesh_terms: D000818:Animals; D004247:DNA / Q000187:drug effects / Q000378:metabolism*; D004560:Electricity; D000431:Ethanol / Q000494:pharmacology; D011166:Porphyrins / Q000378:metabolism*; D012474:Salmon; D013053:Spectrophotometry
chemical_list: D011166:Porphyrins; C021096:tetra(4-N-methylpyridyl)porphine; D000431:Ethanol; D004247:DNA