Usefulness of different myocardial sampling zones for the postmortem diagnosis of myocardial infarction.
The diagnosis of myocardial infarction requires the use of a group of tests that are very efficient, quick and inexpensive. Another important consideration is the choice of myocardial sampling zones, especially in cases of differential diagnosis between a cardiac injury secondary to a trauma or violent asphyxia and others, secondary to myocardial infarction. The aim of this work was to choose, through discriminant analysis, the most useful zones of cardiac tissue for the quantification of free fatty acids and free carnitine and for the performance of the K/Na quotient, as biochemical parameters for the postmortem diagnosis of myocardial infarction. According to the discriminant analysis performed, seven zones of cardiac tissue are necessary to achieve a differential diagnosis among "myocardial infarction," "other natural deaths," and "violent deaths" with a 71.9% efficacy. Greater diagnostic efficacy was found (78.1%) for differentiating between "natural deaths" and "violent deaths."
Lachica
E
E
Cátedra de Medicina Legal, University of Granada, Facultad de Medicina, Spain.
Luna
A
A
Villanueva
E
E
D002331:Carnitine / Q000032:analysis; D003645:Death, Sudden / Q000473:pathology*; D003937:Diagnosis, Differential; D005230:Fatty Acids, Nonesterified / Q000032:analysis; D006346:Heart Septum / Q000473:pathology; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D009203:Myocardial Infarction / Q000473:pathology*; D009206:Myocardium / Q000473:pathology*; D011188:Potassium / Q000032:analysis; D012964:Sodium / Q000032:analysis; D013048:Specimen Handling / Q000379:methods*
D005230:Fatty Acids, Nonesterified; D012964:Sodium; D011188:Potassium; D002331:Carnitine