Ultrastructural studies on interactions of choriocarcinoma cells with stromal cells in monolayers.
Choriocarcinoma is a common cancer in the tropical and subtropical areas including Taiwan, Hong Kong and Japan. An experimental model consisting of monolayer of decidual or smooth muscle cells growing on collagen gels was established to study the invasiveness of choriocarcinoma cells in vitro. It was found that tumour cells induced retraction of stromal cells in the process of invasion.
Chew
E C
EC
Department of Anatomy, Faculty of Medicine, Chinese University of Hong Kong, Shatin, N. T.
Cheung
S L
SL
D000818:Animals; D002450:Cell Communication; D002478:Cells, Cultured; D002822:Choriocarcinoma / Q000473:pathology / Q000503:physiopathology / Q000648:ultrastructure*; D003094:Collagen; D005260:Female; D005318:Fetal Heart; D006801:Humans; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D009206:Myocardium / Q000166:cytology / Q000648:ultrastructure; D009361:Neoplasm Invasiveness; D011247:Pregnancy; D051381:Rats; D014594:Uterine Neoplasms / Q000473:pathology / Q000503:physiopathology / Q000648:ultrastructure*
D003094:Collagen