Camelliin B and nobotanin I, macrocyclic ellagitannin dimers and related dimers, and their antitumor activity.
Camelliin B and nobotanin I, dimeric hydrolyzable tannins of a new class having macrocyclic structures, were isolated from Camellia japonica and Heterocentron roseum, respectively. Nobotanin G and H of the structures related to nobotanin I, were also obtained from H. roseum. Camelliin B and also woodfordin C, a macrocyclic dimer from Woodfordia fruticosa, exhibited marked host-mediated antitumor activities.
Yoshida
T
T
Chou
T
T
Haba
K
K
Okano
Y
Y
Shingu
T
T
Miyamoto
K
K
Koshiura
R
R
Okuda
T
T
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000302:isolation & purification* / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D047348:Hydrolyzable Tannins; D007274:Injections, Intraperitoneal; D051379:Mice; D012510:Sarcoma 180 / Q000188:drug therapy; D013634:Tannins / Q000302:isolation & purification / Q000494:pharmacology*
D000972:Antineoplastic Agents, Phytogenic; D047348:Hydrolyzable Tannins; D013634:Tannins; C063355:nobotanin I; C063356:camelliin B