title: Immunological screening of welders.
abstract: 74 healthy welders were subjected to immunological screening. Serum immunoglobulins (IgG, IgA, IgM) were measured as well as total and active E-RFC and cellular immunity was evaluated using the intradermal testing of PPD, candidin D-7, trichophytin D-5 and tetanus anatoxin. The obtained results suggest suppression of the T and B lymphocyte immune systems as expressed by decreased levels of serum IgG and total E-RFC. Cell-mediated immune deficiency was found in 21.6% welders. Suppression of the immune system may be accounted for by a complex effect of occupational factors, such as manganese compounds, vibration and noise.
authors.affiliation: Department of Biology, Higher Medical Institute, Varna, Bulgaria.
authors.forename: E
authors.initials: E
authors.lastname: Boshnakova
authors.forename: H
authors.initials: H
authors.lastname: Divanyan
authors.forename: I
authors.initials: I
authors.lastname: Zlatarov
authors.forename: S
authors.initials: S
authors.lastname: Marovsky
authors.forename: K
authors.initials: K
authors.lastname: Kisyova
authors.forename: D
authors.initials: D
authors.lastname: Zanev
authors.forename: G
authors.initials: G
authors.lastname: Karev
authors.forename: T
authors.initials: T
authors.lastname: Marinova
mesh_terms: D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology; D002031:Bulgaria; D004781:Environmental Exposure; D006801:Humans; D007108:Immune Tolerance; D007074:Immunoglobulin G / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D008345:Manganese / Q000009:adverse effects; D008875:Middle Aged; D015166:Monitoring, Immunologic; D013601:T-Lymphocytes / Q000276:immunology; D014896:Welding
chemical_list: D007074:Immunoglobulin G; D007136:Immunoglobulins; D008345:Manganese