Ocular toxicity of tamoxifen.
Tamoxifen is a preferred agent for the treatment of breast cancer. While efficacious, it is not without serious side effects. Ocular toxicity to the cornea, retina, and optic nerve have been reported. We present a case of tamoxifen retinopathy and emphasize the need for periodic ophthalmologic examinations to prevent loss of vision.
Gerner
E W
EW
Department of Ophthalmology, Wills Eye Hospital, Philadelphia, PA.
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000188:drug therapy*; D005260:Female; D005451:Fluorescein Angiography; D006258:Head and Neck Neoplasms / Q000188:drug therapy / Q000556:secondary; D006801:Humans; D008535:Megestrol / Q000627:therapeutic use; D008875:Middle Aged; D012164:Retinal Diseases / Q000139:chemically induced*; D013629:Tamoxifen / Q000009:adverse effects*; D014792:Visual Acuity
D013629:Tamoxifen; D008535:Megestrol