title: Suppression of the DTH reaction in mice by means of moxibustion at electro-permeable points.
abstract: The effects of moxibustion stimulation on picryl chloride-induced cutaneous contact hypersensitivity, a delayed type of hypersensitivity (DTH) reaction, were investigated in mice. Three electro-permeable points (B-20, LI-15, S-36) were selected as moxibustion points. Moxibustion at point B-20 (spleen associated point) significantly suppressed the DTH reaction. Adoptive transfer of spleen T cells from moxibustion-stimulated donors resulted in an increased suppression of the DTH reaction in the recipients. These studies suggest that suppression of the DTH reaction with moxibustion may be related to cellular immunity, especially to the induction of the suppressive activity of T cells in the spleen.
authors.affiliation: Kansai College of Acupuncture Medicine, Osaka, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Tohya
authors.forename: F
authors.initials: F
authors.lastname: Mastrogiovanni
authors.forename: R
authors.initials: R
authors.lastname: Sugata
authors.forename: M
authors.initials: M
authors.lastname: Ohnishi
authors.forename: K
authors.initials: K
authors.lastname: Kuroiwa
authors.forename: S
authors.initials: S
authors.lastname: Toda
authors.forename: M
authors.initials: M
authors.lastname: Kimura
authors.forename: J
authors.initials: J
authors.lastname: Kawamata
mesh_terms: D015669:Acupuncture Points; D000818:Animals; D003877:Dermatitis, Contact / Q000473:pathology / Q000517:prevention & control*; D004423:Ear / Q000473:pathology; D005260:Female; D007111:Immunity, Cellular; D007116:Immunization, Passive; D051379:Mice; D008807:Mice, Inbred BALB C; D009071:Moxibustion; D010853:Picryl Chloride; D013601:T-Lymphocytes / Q000276:immunology / Q000637:transplantation
chemical_list: D010853:Picryl Chloride