Monovalent cation specificity of passive transport mediated by laidlomycin and 26-deoxylaidlomycin.
The capacity of laidlomycin (I) and the new 26-deoxylaidlomycin (II) to facilitate passive fluxes of cations through a layer of organic solvent (CHCl3/n-heptane) was estimated in comparison to monensin A (III). While II displayed a 10fold higher transport rate for sodium as compared to calcium, laidlomycin (I) was distinguishable by mediating approx. 100 times lower conveyance of the divalent cations.
Gräfe
U
U
Akademie der Wissenschaften der DDR, Zentral-institut für Mikrobiologie und experimentelle Therapie, Jena.
Reinhardt
G
G
Miosga
N
N
D000900:Anti-Bacterial Agents / Q000378:metabolism*; D001692:Biological Transport; D002118:Calcium / Q000378:metabolism; D015394:Molecular Structure; D008985:Monensin / Q000031:analogs & derivatives* / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism
D000900:Anti-Bacterial Agents; C062367:26-deoxylaidlomycin; D008985:Monensin; D012964:Sodium; C010208:laidlomycin; D002118:Calcium