Frequency of sister chromatid exchanges induced by trimethyltin chloride in human peripheral blood lymphocytes as related to age of donors. A brief report.
Two concentrations (0.5 microgram and 1.0 microgram) of trimethyltin chloride were added to lymphocytes of healthy male and female donors of different age groups and cultured at 37 degrees C for 72 h. The range and mean number of sister chromatid exchanges were significantly increased in the treated cells but could not be related to age or sex of the donor.
Ghosh
B B
BB
Department of Botany, University of Calcutta, India.
Talukder
G
G
Sharma
A
A
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002648:Child; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007223:Infant; D008214:Lymphocytes / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D012854:Sister Chromatid Exchange / Q000187:drug effects*; D014220:Trialkyltin Compounds / Q000494:pharmacology*; D014298:Trimethyltin Compounds / Q000494:pharmacology*
D014220:Trialkyltin Compounds; D014298:Trimethyltin Compounds; C040533:trimethyltin chloride