[Hypertension and angiographically defined coronary heart disease].
The associations of CHD, as defined by coronary arteriography, with hypertension history and causal blood pressure in 103 CHD cases and 103 non-CHD controls matching on sex, race, age(within 3 years)was studied. The odds ratio (i.e.OR) of CHD for patients with hypertension history is 4.64. For patients with higher causal blood pressure, it is 3.53 with both 99% confidence intervals not include 1. There are significant dose-response relationships between level of systolic hypertension and duration of hypertension with regards to odds ratio of CHD or the degree of coronary atherosclerosis. The relative risk of CHD may reduce 70-80% for hypertension patients by taking drugs to lower blood pressure. There are significant correlation between hypertension and myocardial infarction in clinical types of CHD. The CHD average incubation period caused by hypertension is 10 years. It is concluded that the relationship between hypertension and CHD is seemingly causality with part of patients suffering from other consequences.
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D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D017023:Coronary Angiography; D003327:Coronary Disease / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D008297:Male; D016017:Odds Ratio