Hypertension and cardiac complications in normotensive myocardial infarction patients with elevated exercise blood pressure.
Four hundred and sixty-two patients with uncomplicated transmural cardiac infarction were investigated to determine the influence of isolated exercise hypertension on the subsequent development of hypertension (group I, n = 180) and its clinical course (group II, n = 282). Of the infarcted patients with an elevated exercise blood pressure, 83% developed manifest hypertension within 5 years, compared with only 3% with normal exercise blood pressures. Within an observation period of 6 years, the cardiac infarction patients with exercise hypertension suffered a fourfold higher rate of complications than those with normal exercise blood pressures. With elevated exercise blood pressures the mortality rate was 26% and the reinfarction rate 16%, compared with only 5 and 4%, respectively, in patients with normal exercise blood pressure. In addition to the severity of coronary ischaemia and the degree of ventricular impairment, isolated exercise hypertension carried a further unfavourable prognosis.
Patyna
W D
WD
Klinik Westfalen-Lippe, Bad Nauheim, Federal Republic of Germany.
Gemeinhardt
D G
DG
Mitrovic
V
V
D000328:Adult; D001794:Blood Pressure / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications* / Q000503:physiopathology; D011379:Prognosis; D013997:Time Factors