[The cytogenetic action of x-ray irradiation on the myelokaryocytes of rats immunized with a tularemia vaccine].
Immunization with tularemic live dry vaccine administered singularly to Wistar rats skin has been studied for its effect on mutagenicity induced after whole-body X irradiation. The analysis has shown that cytogenetic disturbance induced after X irradiation with doses of 0.5 Gy and 1.0 Gy in immunized animals significantly decreases as compared to nonimmunized animals.
Nersesian
A K
AK
Kumkumadzhian
V A
VA
Zil'fian
V N
VN
D000818:Animals; D001428:Bacterial Vaccines / Q000276:immunology*; D001853:Bone Marrow / Q000187:drug effects / Q000528:radiation effects* / Q000648:ultrastructure; D002869:Chromosome Aberrations / Q000235:genetics*; D003078:Colchicine / Q000494:pharmacology; D004307:Dose-Response Relationship, Radiation; D005604:Francisella tularensis / Q000276:immunology*; D007114:Immunization / Q000379:methods*; D008297:Male; D011836:Radiation Tolerance / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D014613:Vaccines, Attenuated / Q000276:immunology
D001428:Bacterial Vaccines; D014613:Vaccines, Attenuated; D003078:Colchicine
Izuchenie tsitogeneticheskogo deĭstviia rentgenovskogo oblucheniia na mielokariotsity krys, immunizirovannykh tuliaremiĭnoĭ vaktsinoĭ.