[The effect of various types of oxygenators on the pulmonary microvessels and surfactant activity].
Experiments were conducted on 28 dogs to study the changes of microvessels and their effect on the functional condition of pulmonary surfactants after 120-minute venoarterial perfusion and extrapulmonary gas exchange with the use of a foamy-film oxygenator and a "Sever" membrane oxygenator. A direct relationship between the condition of the microvessels and changes of pulmonary surfactant activity was revealed: factors (contact type oxygenators) causing an unfavourable effect on the terminal link of pulmonary circulation induced rapid (in 2-3 hours) development of disturbances in the surfactant system. These changes are less marked in membrane oxygenation.
Skorik
V I
VI
Perezhogin
E V
EV
Gaĭvoronskiĭ
I V
IV
Malikova
T M
TM
D000818:Animals; D004285:Dogs; D005260:Female; D008168:Lung / Q000098:blood supply*; D008297:Male; D008833:Microcirculation / Q000502:physiology; D010106:Oxygenators; D010107:Oxygenators, Membrane; D010477:Perfusion / Q000295:instrumentation / Q000379:methods; D011663:Pulmonary Surfactants / Q000502:physiology*; D013997:Time Factors
D011663:Pulmonary Surfactants
Vliianie oksigenatorov raznogo tipa na mikrososudy i aktivnost' surfaktantov legkikh.