title: [Amino acid composition, heterogeneity and antiheparin activity of protamine sulfate from the milt roe of the sturgeon Acipenser sturio].
abstract: The homogeneous preparation of protamine sulphate is obtained chromatographically and electrophoretically from milt roe of the sturgeon. Its amino acid composition and properties are studied. The methods to blockade the functional groups of protamine sulphate amino acids is used to investigate the possible mechanism of heparin inactivation.
authors.forename: I N
authors.initials: IN
authors.lastname: Borodinskaia
authors.forename: I F
authors.initials: IF
authors.lastname: Mishunin
mesh_terms: D000596:Amino Acids / Q000032:analysis*; D000818:Animals; D002852:Chromatography, Ion Exchange; D005399:Fishes / Q000378:metabolism*; D006494:Heparin Antagonists; D008297:Male; D011479:Protamines / Q000032:analysis* / Q000494:pharmacology; D013094:Spermatozoa / Q000032:analysis*
chemical_list: D000596:Amino Acids; D006494:Heparin Antagonists; D011479:Protamines
vernacular_title: Aminokislotnyĭ sostav, geterogennost' i antigeparinovaia aktivnost' protamina sul'fata molok osetra Acipenser sturio.