Expression of the human relaxin gene in the corpus luteum of the menstrual cycle and in the prostate.
DNA-RNA hybridization has been used to assess the presence of relaxin gene transcripts in human luteal tissues of pregnancy and the menstrual cycle, as well as in the human testis and prostate. The results imply a substantial capacity for hormone biosynthesis in the mid to late luteal phase of the ovary in non-pregnant women. In men the prostate has been shown also to express relaxin gene transcripts, though levels are low. The testis appears negative. The results suggest that functions for relaxin must be sought also outside pregnancy.
Ivell
R
R
Institute for Hormone and Fertility Research, Hamburg, F.R.G.
Hunt
N
N
Khan-Dawood
F
F
Dawood
M Y
MY
D001483:Base Sequence; D015152:Blotting, Northern; D003338:Corpus Luteum / Q000378:metabolism*; D005260:Female; D015870:Gene Expression / Q000502:physiology*; D006801:Humans; D008297:Male; D008597:Menstrual Cycle; D008969:Molecular Sequence Data; D011467:Prostate / Q000378:metabolism*; D012065:Relaxin / Q000235:genetics* / Q000378:metabolism
D012065:Relaxin