Impaired histamine binding by gastric juice of patients with duodenal ulcer.
Histamine binding by gastric juice from 32 patients with duodenal ulcer and 22 control subjects was tested in vitro. The patients had substantially decreased histamine binding both in basal output as well as in pentagastrin stimulated output. The authors suggest that this phenomenon is involved in etiopathogenesis of chronic ulcer disease.
Zak-Nejmark
T
T
Department of Internal Diseases, Medical Academy, Wrocław.
Małolepszy
J
J
Liebhart
J
J
Kuczyńska-Sekieta
K
K
Liebhart
E
E
Nadobna
G
G
D000328:Adult; D000368:Aged; D004381:Duodenal Ulcer / Q000378:metabolism*; D005260:Female; D005750:Gastric Juice / Q000378:metabolism*; D006632:Histamine / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged
D006632:Histamine