Efficacy of RM110, a novel trypanocide, in the treatment of Trypanosoma evansi infections in camels.
Camels artificially infected with a field stock of Trypanosoma evansi isolated from a camel near Gewane, Ethiopia were cured by treatment with RM110, administered by subcutaneous injection at 0.3 or 0.6 mg/kg body weight. Local reactions were mild and transient. Further evaluation of RM110 is indicated, in particular the determination of minimum curative doses for this and other T. evansi stocks in camels.
Zelleke
D
D
Veterinary Services Department, Ministry of Agriculture, Addis Ababa, Ethiopia.
Kassa
B
B
Abebe
S
S
D000818:Animals; D001152:Arsenicals / Q000009:adverse effects / Q000627:therapeutic use*; D001835:Body Weight / Q000187:drug effects; D002162:Camelus / Q000469:parasitology*; D005260:Female; D006400:Hematocrit / Q000662:veterinary; D008297:Male; D051379:Mice; D014344:Trypanocidal Agents / Q000009:adverse effects / Q000627:therapeutic use*; D014353:Trypanosomiasis, African / Q000097:blood / Q000188:drug therapy / Q000662:veterinary*
D001152:Arsenicals; D014344:Trypanocidal Agents; C062789:melaminylthioarsenate