title: [Protein kinase C is not involved in regulating the short-term cholinoreceptor plasticity of the PPa3 and LPa3 neurons of the edible snail].
abstract: A voltage clamp technique on identified Helix lucorum's RPa3 and LPa3 neurons has been used to negate the effect of protein kinase C on extinction of response to repeated iontophoretic applications of acetylcholine to soma. Extracellular influence of phorbol ether, protein kinase C activator (12-O-tetradecanoylphorbol-13-acetate, 0.1-10 mumol/l), or polymyxin B, its blocker (100-500 mumol/l), do not affect the extinction of acetylcholine-induced neuronal response. The data show that protein kinase C is not involved into molecular mechanisms responsible for the regulation of short-term plasticity of RPa3 and LPa3 neuronal cholinoreceptors in Helix lucorum.
authors.forename: A S
authors.initials: AS
authors.lastname: Pivovarov
authors.forename: E I
authors.initials: EI
authors.lastname: Drozdova
authors.forename: B I
authors.initials: BI
authors.lastname: Kotliar
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D004558:Electric Stimulation; D006372:Helix, Snails / Q000502:physiology*; D066298:In Vitro Techniques; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D009473:Neuronal Plasticity / Q000187:drug effects / Q000502:physiology*; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D011112:Polymyxin B / Q000494:pharmacology; D011493:Protein Kinase C / Q000502:physiology*; D011950:Receptors, Cholinergic / Q000187:drug effects / Q000502:physiology*; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D013997:Time Factors
chemical_list: D011950:Receptors, Cholinergic; D011493:Protein Kinase C; D011112:Polymyxin B; D000109:Acetylcholine; D013755:Tetradecanoylphorbol Acetate
vernacular_title: Proteinkinaza C ne vovlechena v reguliatsiiu kratkovremennoĭ plastichnosti kholinoretseptorov neĭronov PPa3 i LPa3 vinogradnoĭ ulitki.