title: [Pathogenetic mechanisms of the development of the cephalgic form of premenstrual syndrome in patients of older age groups].
abstract: Measurements of the blood plasma gonadotropic hormones, sex steroids, and biogenic amines, and investigation of the patterns of vegetative reactions to functional tests during both menstrual cycle phases, carried out in 26 patients with the cephalgic form of the premenstrual syndrome, aged 39-49, and in 13 age-matched women without this syndrome, have shown the contribution of changes in progesterone, serotonin, and histamine levels to the pathogenesis of this condition. These studies have also demonstrated a reduction of the adaptive potentials of the body, i. e. no regular rise of the tone and functional activity of the autonomic nervous system sympathoadrenal section in the lutein phase of the cycle, as well as the development of inadequate reactions in some patients aged 44-49, in whom the disease runs the most severe and long course.
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Komarova
authors.forename: E M
authors.initials: EM
authors.lastname: I'lina
authors.forename: V E
authors.initials: VE
authors.lastname: Balan
mesh_terms: D000328:Adult; D000367:Age Factors; D002979:Climacteric / Q000097:blood*; D005260:Female; D006261:Headache / Q000097:blood / Q000209:etiology*; D006632:Histamine / Q000097:blood; D006801:Humans; D008875:Middle Aged; D011293:Premenstrual Syndrome / Q000097:blood / Q000209:etiology*; D011374:Progesterone / Q000097:blood; D012701:Serotonin / Q000097:blood
chemical_list: D012701:Serotonin; D011374:Progesterone; D006632:Histamine
vernacular_title: Patogeneticheskie mekhanizmy vozniknoveniia tsefalgicheskoĭ formy premenstrua'lnogo sindroma u bo'lnykh starshikh vozrastnykh grupp.