[Prenatal diagnosis of a translocation (X;Y) and genetic counseling].
A cytogenetic prenatal diagnosis due to maternal age led us to find a male fetus with a (X;Y) translocation. This translocation is found in the mother, who presents no phenotypic abnormalities or mental retardation. The 22 cases described in the literature indicate that among male carriers of an (X;Y) translocation, half the cases present mental retardation and 2/3 phenotypic anomalies. These findings led us to give a genetic counselling of therapeutic abortion. Post mortem histological examination revealed no morphodysplasia.
Stora-de Novion
H
H
Petit
C
C
Raynaud
S
S
Ayraud
N
N
D000032:Abortion, Therapeutic; D002869:Chromosome Aberrations / Q000175:diagnosis*; D002871:Chromosome Banding; D025063:Chromosome Disorders; D005817:Genetic Counseling; D006801:Humans; D011296:Prenatal Diagnosis; D014178:Translocation, Genetic; D014960:X Chromosome; D014998:Y Chromosome
Dépistage prénatal d'une translocation (X;Y) et conseil génétique.