title: [Senile type atopic dermatitis].
abstract: Twenty-five patients older than 50 years with atopic dermatitis (AD) diagnosed by the criteria of Tokyo Medical College were investigated on the basis of clinical course and features, IgE RIST, skin reactions, IgE RAST score to several antigens, and IgG4 levels in order to clarify the character of senile AD. The results were compared with the data from younger patients. It was found that the senile type AD showed various type of eczematous lesions whose onset was in the fourth decade of life, and higher IgE RIST and IgG4 levels than healthy people, but lower than younger AD patients. Immediate skin reactions to dermatophagoides and house dust were highly positive in the senile group like the younger group, while the reaction to spices was more highly positive (43%) than in younger persons. Clinically the recognition of the existence of senile type AD and the introduction of antiallergic therapy for severe eczema of old persons are important.
authors.forename: T
authors.initials: T
authors.lastname: Kawashima
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: M
authors.initials: M
authors.lastname: Miyano
authors.forename: N
authors.initials: N
authors.lastname: Ohya
authors.forename: C
authors.initials: C
authors.lastname: Naruse
authors.forename: Y
authors.initials: Y
authors.lastname: Tokuda
mesh_terms: D000367:Age Factors; D000368:Aged; D003876:Dermatitis, Atopic / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000378:metabolism; D007074:Immunoglobulin G / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D012882:Skin Tests
chemical_list: D007074:Immunoglobulin G; D007073:Immunoglobulin E