[The acetylator phenotype in patients with urinary bladder cancer].
In 53 patients suffering from bladder cancer the acelylization phenotype was examined. The frequency of slow acetylizers (70%) was significantly higher than in the control group. The more frequently occurrence of slow acetylizers in the group with professional pollutant exposition is an important reference to a higher bladder cancer morbidity in the case of carcinogen contact. A screening of the acetylization phenotype in professions with carcinogen contact may be important in the prophylaxis of bladder cancer.
Wich
H
H
Urologische Klinik, Bezirkskrankenhauses Heinrich Braun Zwickau.
Franke
G
G
Grimm
U
U
Siegmund
W
W
D000107:Acetylation; D002273:Carcinogens / Q000493:pharmacokinetics; D006801:Humans; D008658:Inactivation, Metabolic / Q000235:genetics*; D010641:Phenotype; D012307:Risk Factors; D013418:Sulfamethazine; D001749:Urinary Bladder Neoplasms / Q000139:chemically induced / Q000235:genetics*
D002273:Carcinogens; D013418:Sulfamethazine
Zum Azetylierungsphänotyp bei Harnblasenkarzinompatienten.