1,2,4-triazoles, III: new 1,5-diaryl-3-(substituted amino)-1H-1,2,4-triazoles as anti-inflammatory agents.
A series of 1,5-diaryl-3-(substituted amino)-1 H-1,2,4-triazoles was synthesized and assayed in the rat adjuvant induced arthritis model. Several compounds showed significant anti-inflammatory activity.
Bozó
E
E
Szilágyi
G
G
Janáky
J
J
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis* / Q000494:pharmacology; D005260:Female; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D014230:Triazoles / Q000138:chemical synthesis* / Q000494:pharmacology
D000894:Anti-Inflammatory Agents, Non-Steroidal; D014230:Triazoles