[Study on quality of gossypol recrystalized from chloroform].
In this paper, the chemical properties of gossypol recrystalized from chloroform are described. Samples were dried at different temperatures at reduced pressure, and stored under room temperature for different times. They were identified and determined by melting point, thin layer chromatography, UV spectrophotometry, IR spectrophotometry, thermo-gravimetric analysis, X-ray diffraction, elementary analysis and also for the content of gossypol. The results of these tests proved gossypol to be solvated with chloroform at low temperature. This phenomenon decreased gradually with increase of drying temperature or storage time, and the content of gossypol increased accordingly. The presence of chloroform in the crystal interferes with the purity of gossypol. Thus, it is necessary to identify the presence of chloroform with oxygen flask ombustion-mercurimetry beforehand.
Han
S D
SD
Jiang
D H
DH
Wang
J L
JL
D002725:Chloroform / Q000032:analysis; D003460:Crystallization; D006072:Gossypol / Q000032:analysis; D012997:Solvents
D012997:Solvents; D002725:Chloroform; D006072:Gossypol