Relationship between intracellular dCTP/ara-CTP ratio and cytotoxic effect of ara-C.
Kawasaki
H
H
Mie Univ. School of Med., Dep. of Ped., Tsu City, Japan.
Higashigawa
M
M
Ohkubo
T
T
Kamiya
H
H
Sakurai
M
M
D000818:Animals; D001085:Arabinofuranosylcytosine Triphosphate / Q000032:analysis*; D001088:Arabinonucleotides / Q000032:analysis*; D003561:Cytarabine / Q000378:metabolism / Q000494:pharmacology*; D003845:Deoxycytosine Nucleotides / Q000032:analysis*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007951:Leukemia, Myeloid / Q000473:pathology*; D015458:Leukemia, T-Cell / Q000473:pathology*; D051379:Mice; D013154:Spleen / Q000166:cytology / Q000187:drug effects; D013997:Time Factors; D014407:Tumor Cells, Cultured
D001088:Arabinonucleotides; D003845:Deoxycytosine Nucleotides; D003561:Cytarabine; D001085:Arabinofuranosylcytosine Triphosphate; C024107:2'-deoxycytidine 5'-triphosphate