[Study of talc for pharmaceutical use. Trials of pharmacopoeias].
A study has been carried out on the possible pharmaceutical use of spanish talcs following the normalized assays of the main european pharmacopoeia and other quantitative methods. Only the talc nr3, not processed, meets all the assays of pharmacopoeia. The samples 2 and 4 (crushed) exceed the highest tolerated content in chlorides. The talc 1 (also crushed) only meets the loss on drying. The measures of some of these assays by using quantitative methods lead to more correct results and even sometimes in opposition with those obtained by pharmacopoeia methods. The particle size estimated by shifting and sedimentation shows that the crushed talcs are silty, whereas the only talc not processed is sandy. Considering the medium sizes estimated by scanning microscopy, it can be said that the pulverization of the talcs 1, 2 and 4 is characteristic of a micronization.
Gamiz
E
E
Delgado Calvo-Flores
G
G
Parraga
J
J
Delgado Calvo-Flores
R
R
D010316:Particle Size; D010602:Pharmacopoeias as Topic; D013030:Spain; D013627:Talc / Q000032:analysis* / Q000592:standards
D013627:Talc
Etude de talcs à usage pharmaceutique. Essais des pharmacopées.