Detection of human serum amyloid A protein in very low density--and high density lipoproteins of patients after acute myocardial infarction.
Two acute-phase proteins have been identified in very low density (VLDL)- and high density lipoproteins (HDL) of patients after acute myocardial infarction. Both proteins have a relative molecular weight of 11,000 and isoelectric points pI 6.08 and 6.27, and do not contain cysteine or sugar residues. Polyclonal antibodies to these acute phase reactants did not cross-react with other serum apolipoproteins. Evidence is given that both proteins are polymorphic forms of the human serum amyloid A protein.
Feussner
G
G
Abteilung Innere Medizin I, Medizinische Universitätsklinik, Heidelberg, Federal Republic of Germany.
Ziegler
R
R
D015153:Blotting, Western; D015180:Electrophoresis, Gel, Two-Dimensional; D006801:Humans; D007525:Isoelectric Focusing; D008077:Lipoproteins, LDL / Q000378:metabolism*; D008079:Lipoproteins, VLDL / Q000378:metabolism*; D009203:Myocardial Infarction / Q000378:metabolism*; D000685:Serum Amyloid A Protein / Q000032:analysis*
D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D000685:Serum Amyloid A Protein