[The combined and separate use of prostaglandin and adrenergic agents for the purpose of the experimental correction of uterine contractile activity].
Experiments on pregnant rats revealed that a combination of low doses of partusisten and clophelin (1.25 mg/kg and 0.15 ml of 0.001% solution, respectively) potentiated a tocolytic effect. A combination of prostenon and oxytocin given in half doses (0.15 mg/kg and 0.25 IU in 0.1 ml, respectively) summarized their stimulant effect on the myometrium. Premedication with partusisten (2.5 micrograms/kg) failed to change the stimulant effect produced by a combination of prostenon and oxytocin given in half doses.
Korkhov
V V
VV
Sulukhiia
R V
RV
Mats
M N
MN
D000818:Animals; D003000:Clonidine / Q000008:administration & dosage; D015232:Dinoprostone / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D005260:Female; D005280:Fenoterol / Q000008:administration & dosage; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D010121:Oxytocin / Q000008:administration & dosage; D011247:Pregnancy; D051381:Rats; D013566:Sympathomimetics / Q000008:administration & dosage*; D014590:Uterine Contraction / Q000187:drug effects* / Q000502:physiology
D013566:Sympathomimetics; D005280:Fenoterol; D010121:Oxytocin; D015232:Dinoprostone; D003000:Clonidine
Sochetannoe i razdel'noe primenenie prostaglandina i adrenergicheskikh sredstv s tsel'iu korrektsii sokratitel'noĭ deiatel'nosti matki v éksperimente.