title: Crystallization and preliminary crystallographic data for bovine antithrombin III.
abstract: Crystals of bovine antithrombin III were obtained in the presence of metal ions with ammonium sulphate as precipitating agent. Crystals belong to space group P4(1)2(1)2 or P4(3)2(1)2 with cell parameters a = b = 91.4 A, c = 383.1 A; there are two molecules per asymmetric unit. Electrophoresis experiments and amino acid sequence analysis of the N-terminal part of redissolved crystals suggest that the protein molecules are cleaved at the active site.
authors.affiliation: Laboratoire de Cristallographie Biologique, I.B.M.C. du C.N.R.S., Strasbourg, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Samama
authors.forename: M
authors.initials: M
authors.lastname: Delarue
authors.forename: L
authors.initials: L
authors.lastname: Mourey
authors.forename: J
authors.initials: J
authors.lastname: Choay
authors.forename: D
authors.initials: D
authors.lastname: Moras
mesh_terms: D000818:Animals; D000990:Antithrombin III / Q000648:ultrastructure*; D002417:Cattle; D003461:Crystallography; D011487:Protein Conformation; D014961:X-Ray Diffraction
chemical_list: D000990:Antithrombin III