Regional assignment of nonspecific cross-reacting antigen (NCA) of the CEA gene family to chromosome 19 at band q13.2.
Nonspecific cross-reacting antigen (NCA) is a member of the carcinoembryonic antigen (CEA) gene family. Recently, a DNA segment for part of the human NCA gene was isolated and sequenced. We mapped this gene by Southern blot analysis of hybrid cells and by in situ hybridization. The Southern blot analysis indicated that the NCA gene is on human chromosome 19 and the in situ hybridizations localized the gene to band 19q13.2.
Inazawa
J
J
Department of Hygiene, Kyoto Prefectural University of Medicine, Japan.
Abe
T
T
Inoue
K
K
Misawa
S
S
Oikawa
S
S
Nakazato
H
H
Yoshida
M C
MC
D000818:Animals; D015214:Antigens, Differentiation, Myelomonocytic / Q000235:genetics*; D000951:Antigens, Neoplasm; D015139:Blotting, Southern; D002272:Carcinoembryonic Antigen / Q000235:genetics; D015815:Cell Adhesion Molecules; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002888:Chromosomes, Human, Pair 19; D015342:DNA Probes; D004273:DNA, Neoplasm / Q000235:genetics; D006023:Glycoproteins / Q000235:genetics*; D006801:Humans; D006822:Hybrid Cells; D005810:Multigene Family; D009693:Nucleic Acid Hybridization
D015214:Antigens, Differentiation, Myelomonocytic; D000951:Antigens, Neoplasm; D002272:Carcinoembryonic Antigen; D015815:Cell Adhesion Molecules; D015342:DNA Probes; D004273:DNA, Neoplasm; D006023:Glycoproteins