title: Hypoxanthine accumulation and dopamine depletion in Lesch-Nyhan disease.
authors.affiliation: Department of Psychiatry, McGill University, Montreal, Que, Canada.
authors.forename: R M
authors.initials: RM
authors.lastname: Palmour
authors.forename: T W
authors.initials: TW
authors.lastname: Heshka
authors.forename: F R
authors.initials: FR
authors.lastname: Ervin
mesh_terms: D000241:Adenosine / Q000031:analogs & derivatives / Q000494:pharmacology; D019830:Adenosine-5'-(N-ethylcarboxamide); D000818:Animals; D001058:Apomorphine / Q000037:antagonists & inhibitors; D001921:Brain / Q000378:metabolism*; D004298:Dopamine / Q000031:analogs & derivatives / Q000378:metabolism*; D007042:Hypoxanthines / Q000378:metabolism*; D007926:Lesch-Nyhan Syndrome / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D014275:Trigeminal Caudal Nucleus / Q000378:metabolism
chemical_list: D007042:Hypoxanthines; D019830:Adenosine-5'-(N-ethylcarboxamide); D000241:Adenosine; D001058:Apomorphine; D004298:Dopamine