[Treatment of essential hypercholesterolemia by normolipidemic drugs in children].
The authors list the principal normolipidemic drugs. Only cholestyramine (Questran) and some fibrates (fenofibrate: Lipanthyl for instance) are registered for pediatrics. Cholestyramine acts by sequestering biliary acids, and thereby inhibiting intestinal cholesterol resorption. It is the primary drug used for children, when diet has been unable to restore normal cholesterol values.
Boucherle
A
A
Pharmacie CHRU, Grenoble, France.
Calop
J
J
Rossignol
A M
AM
Bost
M
M
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002792:Cholestyramine Resin / Q000494:pharmacology*; D002994:Clofibrate / Q000494:pharmacology*; D011345:Fenofibrate / Q000494:pharmacology; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D006938:Hyperlipoproteinemia Type II / Q000188:drug therapy*; D007223:Infant; D007231:Infant, Newborn; D009539:Nicotinic Acids / Q000494:pharmacology; D013455:Sulfur / Q000494:pharmacology
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D009539:Nicotinic Acids; D002792:Cholestyramine Resin; D013455:Sulfur; D002994:Clofibrate; D011345:Fenofibrate
Le traitement de l'hypercholestérolémie essentielle de l'enfant par les normolipémiants.