Synthesis of 2'-deoxy-6,2'-methano-pyrimidine nucleosides and optical properties of pyrimidine C-cyclonucleosides.
2'-Deoxy-6,2'-methano derivatives of uridine, cytidine, and 4-thiouridine were synthesized by the Peterson olefination of a ketosugar with a pyrimidine followed by an intramolecular glycosylation reaction. CD-spectra of these cyclonucleosides together with other pyrimidine C-cyclonucleosides were given.
Yoshimura
Y
Y
Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
Matsuda
A
A
Ueda
T
T
D002942:Circular Dichroism; D008968:Molecular Conformation; D011741:Pyrimidine Nucleosides / Q000138:chemical synthesis*
D011741:Pyrimidine Nucleosides