title: [The acetylator phenotype in patients with urinary bladder cancer].
abstract: In 53 patients suffering from bladder cancer the acelylization phenotype was examined. The frequency of slow acetylizers (70%) was significantly higher than in the control group. The more frequently occurrence of slow acetylizers in the group with professional pollutant exposition is an important reference to a higher bladder cancer morbidity in the case of carcinogen contact. A screening of the acetylization phenotype in professions with carcinogen contact may be important in the prophylaxis of bladder cancer.
authors.affiliation: Urologische Klinik, Bezirkskrankenhauses Heinrich Braun Zwickau.
authors.forename: H
authors.initials: H
authors.lastname: Wich
authors.forename: G
authors.initials: G
authors.lastname: Franke
authors.forename: U
authors.initials: U
authors.lastname: Grimm
authors.forename: W
authors.initials: W
authors.lastname: Siegmund
mesh_terms: D000107:Acetylation; D002273:Carcinogens / Q000493:pharmacokinetics; D006801:Humans; D008658:Inactivation, Metabolic / Q000235:genetics*; D010641:Phenotype; D012307:Risk Factors; D013418:Sulfamethazine; D001749:Urinary Bladder Neoplasms / Q000139:chemically induced / Q000235:genetics*
chemical_list: D002273:Carcinogens; D013418:Sulfamethazine
vernacular_title: Zum Azetylierungsphänotyp bei Harnblasenkarzinompatienten.