title: Solid-phase synthesis of oligoribonucleotides.
abstract: An efficient method is described for solid-phase synthesis of oligoribonucleotides that involves use of the 9-fluorenylmethoxycarbonyl group (Fmoc) for 5'-protection, 4-methoxytetrahydropyran-4-yl (Mthp) for 2'-protection and a phosphoramidite coupling procedure.
authors.affiliation: Medical Research Council, Laboratory of Molecular Biology, Cambridge, UK.
authors.forename: Y Z
authors.initials: YZ
authors.lastname: Xu
authors.forename: C
authors.initials: C
authors.lastname: Lehmann
authors.forename: G
authors.initials: G
authors.lastname: Slim
authors.forename: C
authors.initials: C
authors.lastname: Christodoulou
authors.forename: Z K
authors.initials: ZK
authors.lastname: Tan
authors.forename: M J
authors.initials: MJ
authors.lastname: Gait
mesh_terms: D004355:Drug Stability; D005898:Glass; D007202:Indicators and Reagents; D009843:Oligoribonucleotides / Q000138:chemical synthesis*
chemical_list: D007202:Indicators and Reagents; D009843:Oligoribonucleotides