A novel human alloantibody in the Gerbich system.
A Gerbich-negative Leach phenotype individual was identified on the basis of distinct morphological, biochemical, and serological characteristics of her red blood cells. This individual has produced an antibody which was reactive with the various Gerbich phenotypes including Ge:-2,3 (Yus type) and Ge:-2,-3 (Ge type) cells; only her own and Leach phenotype cells were non-reactive. It is suggested that this antibody represents an example of a new specificity, one which defines the Leach phenotype, in the Gerbich system.
McShane
K
K
Canadian Red Cross Society, National Reference Laboratory, Ottawa, Ont.
Chung
A
A
D001789:Blood Group Antigens / Q000276:immunology*; D004912:Erythrocytes / Q000166:cytology* / Q000276:immunology; D005260:Female; D006801:Humans; D007518:Isoantibodies / Q000032:analysis* / Q000276:immunology; D010641:Phenotype
D001789:Blood Group Antigens; D007518:Isoantibodies