title: Monte Carlo modeling of light propagation in highly scattering tissue--I: Model predictions and comparison with diffusion theory.
abstract: Using optical interaction coefficients typical of mammalian soft tissues in the red and near infrared regions of the spectrum, calculations of fluence-depth distributions, effective penetration depths and diffuse reflectance from two models of radiative transfer, diffusion theory, and Monte Carlo simulation are compared for a semi-infinite medium. The predictions from diffusion theory are shown to be increasingly inaccurate as the albedo tends to zero and/or the average cosine of scatter tends to unity.
authors.forename: S T
authors.initials: ST
authors.lastname: Flock
authors.forename: M S
authors.initials: MS
authors.lastname: Patterson
authors.forename: B C
authors.initials: BC
authors.lastname: Wilson
authors.forename: D R
authors.initials: DR
authors.lastname: Wyman
mesh_terms: D008027:Light; D008954:Models, Biological; D009010:Monte Carlo Method; D009874:Operations Research; D012542:Scattering, Radiation; D012867:Skin