Electrophoretic HbA2 assessment in ischemic heart disease.
A series of fifty patients presenting ischemic heart disease are studied. As shown by the electropherogram, apart from the basic band of hemoglobin A2, an additional weaker band appears with a diffuse zone between them. The quantity of the entire HbA2-diffuse zone exceeds by 3.8 per cent the total hemoglobin. Its appearance is not attributed to abnormal hemoglobin or beta-thalassemia. With the passing of time its quantity shows a decrease, and within 3-6 days it disappears. Parallel to normalization of the hemoglobin profile the pain syndrome among patients with unstable stenocardia subsides, and stabilization of the patients with a history of myocardial infarction takes place.
Damyanova
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D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003327:Coronary Disease / Q000097:blood*; D004588:Electrophoresis, Cellulose Acetate; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006441:Hemoglobin A / Q000032:analysis*; D006443:Hemoglobin A2 / Q000032:analysis*; D006801:Humans; D007525:Isoelectric Focusing; D008297:Male; D008875:Middle Aged
D006441:Hemoglobin A; D006443:Hemoglobin A2