Monitoring accumulating data in a clinical trial.
A clinical trial is monitored for efficacy or safety; the variable of interest is death or a similarly serious event. The probability that one therapy has a greater mortality rate than the other is calculated ad libitum during the trial. Adjustments are made for differing patients' prognoses and for survival times.
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School of Statistics, University of Minnesota, Minneapolis 55455.
D001699:Biometry; D002986:Clinical Trials as Topic / Q000706:statistics & numerical data*; D003627:Data Interpretation, Statistical; D006801:Humans; D009026:Mortality; D011336:Probability; D011379:Prognosis