[Cimetidine and ethanol].
Cimetidine inhibits hepatic drug metabolism, but its effect on ethanol elimination is less well established. The influence of cimetidine on the kinetics of ethanol is studied with three standardized drinking experiments. Cimetidine had no influence on the absorption or elimination of ethanol. There were significant differences in distribution of ethanol in consequence of inhibition of vascular histamine receptors after cimetidine application.
Papke
J
J
Inneren Abteilung, Medizinischen Akademie Carl Gustav Carus Dresden.
Borgmann
H
H
Dökert
B
B
Bartels
H
H
Krause
D
D
D000293:Adolescent; D000328:Adult; D002927:Cimetidine / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000493:pharmacokinetics*; D005260:Female; D006801:Humans; D007408:Intestinal Absorption / Q000187:drug effects; D008297:Male; D008657:Metabolic Clearance Rate
D000431:Ethanol; D002927:Cimetidine
Cimetidin und Ethanol.