[Lung thallium uptake for non-invasive assessment of increased pulmonary pressure in mitral valve stenosis].
30 patients (24 females, 5 males) with angiographically proven mitral stenosis as well as 10 healthy controls were investigated by wedge catheterism and thallium-201-scintigraphy to calculate the heart-lung quotient (HLQ) of the isotope. All patients with mitral stenosis could be discriminated from controls by a pathological increase of isotope concentration in the lungs. 4 groups could be subdivided: the 1st group consisted of 21% of the patients with normal pulmonary artery pressure of x = 13.06 mm Hg and a normal HLQ less than 1.1. The 2nd group of 39% of the patients showed passive pulmonary hypertension with a PAm of x = 27.57 mm Hg and HLQ between 1.1 and 1.4 A 3rd group showed PAm of 36.76 mm Hg with reactive pulmonary hypertension and a HLQ between 1.4 and 1.6. The last group showed pulmonary hypertension of x = 45 mm Hg PAm and a HLQ of greater than 1.6. Scintigraphy alone allowed classification of the patients, so the value of this method is proven for pre- and postoperative strategy.
Eichstädt
H
H
Abteilungen Kardiologie und Radiologie, Universitätsklinikum Rudolf Virchow, Standort Charlottenburg, BRD.
Danne
O
O
Bäder
M
M
Schendzielorz
B
B
Kaiser
W
W
Schmutzler
H
H
Felix
R
R
D005080:Exercise Test; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging*; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D008946:Mitral Valve Stenosis / Q000000981:diagnostic imaging*; D011669:Pulmonary Wedge Pressure / Q000502:physiology; D011877:Radionuclide Imaging; D013794:Thallium Radioisotopes; D014655:Vascular Resistance / Q000502:physiology
D013794:Thallium Radioisotopes
Der Lungenthallium-Uptake zur nichtinvasiven Abschätzung der pulmonalen Druckerhöhung bei Mitralstenose.