[A comparative cross-over study of pellet pancreatin and tablet pancreatin in chronic pancreatitis].
We have made a comparative cross study of 30 patients with chronic pancreatitis and steatorrhea. The aim of the study has been to compare the effectiveness of a new galenic form of pancreatin, in pellets, with the common galenic presentation, in tablets. In all the cases the cause of pancreatic failure was alcoholism. In both groups the treatment was administered during seven days, after a period of wash out. We evaluated steatorrhea and clinical symptoms, including the typical abdominal pain. (The doses administrated were 12 tablets/day or 9 pellets/day.) Statistically there was a significant decrease of steatorrhea p less than 0.01.
Herrerías
J M
JM
Gómez Parra
M
M
García Montes
J M
JM
Petit
M A
MA
Valladolid León
J M
JM
D015746:Abdominal Pain / Q000188:drug therapy; D000328:Adult; D002446:Celiac Disease / Q000209:etiology; D002908:Chronic Disease; D004304:Dosage Forms; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010194:Pancreatin / Q000008:administration & dosage* / Q000627:therapeutic use; D010195:Pancreatitis / Q000150:complications / Q000188:drug therapy*; D011897:Random Allocation; D013607:Tablets
D004304:Dosage Forms; D013607:Tablets; D010194:Pancreatin
Estudio comparativo cruzado entre pancreatina en "pellets" y pancreatina en tabletas en pancreatitis crónica.