title: Treatment with locally applied mitoxantrone.
abstract: In 30 patients mitoxantrone was administered via an intracavitary route intraperitoneally, intrapleurally or intrapericardially. From 13 patients with malignant pleural effusion 5 showed a complete and 3 a partial remission. 2 of 2 patients with pericardial effusion showed a complete remission. From 16 patients with peritoneal carcinosis 4 showed a complete and 3 a partial remission.
authors.affiliation: Medizinischen Klinik II für Hämatologie, Onkologie und Immunologle, St. Johannes-Hospital, Duisburg, FRG.
authors.forename: K
authors.initials: K
authors.lastname: Kuhn
authors.forename: H
authors.initials: H
authors.lastname: Purea
authors.forename: J
authors.initials: J
authors.lastname: Selbach
authors.forename: M
authors.initials: M
authors.lastname: Westerhausen
mesh_terms: D002408:Catheters, Indwelling; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D008479:Mediastinal Neoplasms / Q000188:drug therapy / Q000556:secondary*; D008942:Mitoxantrone / Q000008:administration & dosage* / Q000009:adverse effects; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy; D010496:Pericardium / Q000187:drug effects; D010534:Peritoneal Neoplasms / Q000188:drug therapy / Q000556:secondary*; D010997:Pleural Neoplasms / Q000188:drug therapy / Q000556:secondary*
chemical_list: D008942:Mitoxantrone