title: Donor-specific transfusion via the portal venous route induces prolongation of H-2-compatible but not H-2-incompatible cardiac graft survival.
abstract: In the H-2-compatible donor-recipient combination (BALB/c----DBA/2), pretransplant donor-specific blood transfusion (DST) via the portal venous (PV) route significantly prolonged cardiac graft survival. DST via the intravenous (IV) route (systemic circulation) also showed a marked prolongation of heart tissue transplant survival in this model. In the H-2-incompatible combination (BALB/c----CBA/H), DST via the IV - but not via the PV - route resulted in accelerated graft rejection.
authors.affiliation: Department of Histology and Embryology, Institute of Biostructure, Medical School, Warsaw, Poland.
authors.forename: D
authors.initials: D
authors.lastname: Górecki
authors.forename: M
authors.initials: M
authors.lastname: Jakóbisiak
authors.forename: M
authors.initials: M
authors.lastname: Lupińska
authors.forename: A
authors.initials: A
authors.lastname: Kruszewski
authors.forename: J
authors.initials: J
authors.lastname: Czyźyk
mesh_terms: D000818:Animals; D001803:Blood Transfusion / Q000379:methods; D006082:Graft Enhancement, Immunologic / Q000379:methods*; D006085:Graft Survival; D006183:H-2 Antigens; D016027:Heart Transplantation / Q000276:immunology*; D007275:Injections, Intravenous; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D011169:Portal Vein; D014184:Transplantation, Homologous
chemical_list: D006183:H-2 Antigens