title: Prenatal exposure to drugs: behavioral distortions reflecting CNS impairment?
abstract: In order to disentangle the effects on development of prenatal drug exposure from the effects of poor prenatal care, perinatal complications, and low socioeconomic status, toddlers prenatally exposed to drugs were compared to high risk preterm toddlers of similar ethnicity and social class. Intellectual functioning and quality of play were assessed. The drug exposed toddlers had significantly lower developmental scores and less representational play. Furthermore elements of their play were characterized by the investigators as a soft neurological sign. The question of possible CNS impairment is raised.
authors.affiliation: Department of Pediatrics, University of California, Los Angeles 90024.
authors.forename: C
authors.initials: C
authors.lastname: Rodning
authors.forename: L
authors.initials: L
authors.lastname: Beckwith
authors.forename: J
authors.initials: J
authors.lastname: Howard
mesh_terms: D002493:Central Nervous System Diseases / Q000139:chemically induced* / Q000523:psychology; D002652:Child Behavior / Q000187:drug effects*; D002657:Child Development / Q000187:drug effects; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008385:Marijuana Smoking; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D012307:Risk Factors