title: The use of an investigational radiopharmaceutical in neuroblastoma: a nursing perspective.
abstract: Children with advanced-stage neuroblastoma usually have a poor prognosis. While conventional treatment with surgery, chemotherapy, and radiation may provide some palliation, long-term survival is rare. A number of investigational therapies are being performed nationwide in an attempt to improve the prognosis for children with neuroblastoma. One such treatment is the use of 131I-metaiodobenzylguanidine. This article will review the pathophysiology of neuroblastoma, give an overview of this investigational treatment, and discuss the nursing care associated with radioactive treatment.
authors.forename: J U
authors.initials: JU
authors.lastname: Kelly
mesh_terms: D019797:3-Iodobenzylguanidine; D000328:Adult; D002648:Child; D002985:Clinical Protocols; D006801:Humans; D007457:Iodine Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use*; D007462:Iodobenzenes / Q000008:administration & dosage / Q000627:therapeutic use*; D009447:Neuroblastoma / Q000451:nursing / Q000532:radiotherapy*; D010356:Patient Isolation; D011193:Potassium Iodide / Q000627:therapeutic use; D011832:Radiation Injuries / Q000517:prevention & control; D013565:Sympatholytics / Q000627:therapeutic use*; D013961:Thyroid Gland / Q000528:radiation effects
chemical_list: D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D013565:Sympatholytics; D011193:Potassium Iodide; D019797:3-Iodobenzylguanidine