title: Effect of herbicide banvel on rabbit vaginal mucus membrane.
abstract: Effect of banvel and its active ingredient, dicamba (3,6-dichloro-o-anisic acid) was investigated employing rabbit mucus membrane irritancy test. Inflammatory changes which did not exceed an average score of 2+ were observed in the animals 48 hr after a single intravaginal application of banvel (0.1 ml/rabbit) and dicamba (100 mg/rabbit). Persistent histopathological changes were observed in 1 out of 6 banvel-treated rabbits 15 days post-application. The results suggest that banvel and dicamba are not primary irritants but should nevertheless be employed with caution.
authors.forename: P K
authors.initials: PK
authors.lastname: Agnihotri
authors.forename: P S
authors.initials: PS
authors.lastname: Murthy
authors.forename: S K
authors.initials: SK
authors.lastname: Mukherjee
mesh_terms: D000818:Animals; D001565:Benzoates / Q000633:toxicity*; D003996:Dicamba / Q000031:analogs & derivatives / Q000633:toxicity*; D005260:Female; D009092:Mucous Membrane / Q000187:drug effects; D011817:Rabbits; D014621:Vagina / Q000187:drug effects*
chemical_list: D001565:Benzoates; C027233:dicamba dimethylamine; D003996:Dicamba