Improvement in 31P NMR signal-to-noise for ATP in vivo using homonuclear decoupling.
The efficiency of 31P homonuclear decoupling in vivo is demonstrated. In low-field clinical situations, when JPP is equal to or greater than delta v, significant improvements in the precision of measuring the ATP resonance area can be expected upon decoupling due to the increase in signal-to-noise produced upon collapse of the J coupling. The sensitivity loss due to time sharing between the decoupler and receiver is discussed.
Berkowitz
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BA
Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20892.
Balaban
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RS
D000244:Adenosine Diphosphate / Q000032:analysis; D000255:Adenosine Triphosphate / Q000032:analysis*; D000818:Animals; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D010758:Phosphorus; D011817:Rabbits
D010758:Phosphorus; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate