title: Synthesis and antimicrobial activity of some 1-arylideneamino-2-mercaptoimidazole derivatives.
abstract: A new series of 1-arylideneamino-2-mercaptoimidazole derivatives obtained by condensation of 1-amino-2-mercaptoimidazole derivatives with variously substituted aromatic aldehydes is described. Investigation of their antimicrobial properties showed a good antibacterial activity for some of the tested compounds on some gram-positive micro-organisms.
authors.affiliation: Istituto di Chimica Farmaceutica, Tossicologica ed Applicata, Cagliari, Italy.
authors.forename: M T
authors.initials: MT
authors.lastname: Cocco
authors.forename: C
authors.initials: C
authors.lastname: Congiu
authors.forename: A
authors.initials: A
authors.lastname: Maccioni
authors.forename: A
authors.initials: A
authors.lastname: Plumitallo
authors.forename: M L
authors.initials: ML
authors.lastname: Schivo
authors.forename: A
authors.initials: A
authors.lastname: De Logu
mesh_terms: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis*; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D005658:Fungi / Q000187:drug effects; D007093:Imidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D013055:Spectrophotometry, Infrared
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D007093:Imidazoles