[The correlation of serum IgE and IgE-RAST of mite, egg white, milk, soybean, rice and wheat: a study by analysis of regression curves].
The correlation of variation in serum IgE and IgE-RAST in 364 cases of patients with atopic dermatitis (AD) aged 4 months to 78 years was analysed by comparison with the scatter diagram and fifth dimension regression curve representing the serum IgE and IgE-RAST scores of mite, egg white, milk, soybean, wheat and rice. The antigens indicating a high IgE-RAST score varied according to age. They were egg white and milk in infancy and mite from one to fifteen years of age. Rice and wheat came later. A high value of serum IgE with AD was seen to depend on the production of specific mite IgE antibody and to be influenced by each specific IgE antibody production, which varied according to age. It seemed that egg white and milk were initiators of AD and mite acted as a promotor. Rice and wheat were accelerators in patients with adult type AD. It was confirmed that, for AD patients of all ages, improvement of the environmental antigens and diet therapy was necessary.
Fujisawa
S
S
Yamamoto
Y
Y
Hara
H
H
Araki
H
H
Morishima
T
T
Morioka
S
S
Kamata
H
H
Gondo
A
A
Tokuda
Y
Y
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000276:immunology*; D004529:Egg White; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000378:metabolism*; D007223:Infant; D008297:Male; D008875:Middle Aged; D008892:Milk / Q000276:immunology*; D008925:Mites / Q000276:immunology*; D012275:Oryza; D011852:Radioallergosorbent Test; D012044:Regression Analysis; D013025:Glycine max; D014908:Triticum
D007073:Immunoglobulin E