Campylobacter pylori in gastric, duodenal and jejunal juices and mucosae of patients with duodenal ulcer.
The presence of Campylobacter pylori was investigated in biopsies and fluids obtained in the antrum, duodenal bulb and jejunum during jejunoscopy in 20 patients with an active duodenal ulcer. C. pylori was present in cultured antral biopsies in all patients, in the bulb of most patients (16/20), but was unusual in jejunal mucosa (2/20). Using a non-contaminated sampling method of fluid, C. pylori was found in only two samples at each level. In conclusion, C. pylori is frequent in bulbar mucosa of duodenal ulcer patients, rare in jejunal mucosa and in fluid at each level, thus confirming the ecological mucosal niche of C. pylori.
Debongnie
J C
JC
Delmee
M
M
Mainguet
P
P
D000328:Adult; D000368:Aged; D002167:Campylobacter / Q000302:isolation & purification*; D004381:Duodenal Ulcer / Q000382:microbiology*; D005260:Female; D005750:Gastric Juice / Q000382:microbiology; D005753:Gastric Mucosa / Q000382:microbiology; D006801:Humans; D007413:Intestinal Mucosa / Q000382:microbiology*; D007419:Intestinal Secretions / Q000382:microbiology*; D008297:Male; D008875:Middle Aged