[Conservativism of the matrix protein of paramyxoviruses].
Cross reactions among paramyxoviruses were determined by the immunoblot method. Human parainfluenza viruses, types 1-3, avian parainfluenza virus type 4, mumps, Sendai, and measles viruses were used. Antisera to human parainfluenza viruses were shown to cross-interact with proteins NP and M of other types, and all antisera to the members of Paramyxovirus genus cross-reacted with M proteins of other paramyxoviruses. No cross reactions with measles virus proteins were observed. It is concluded that M protein is the most conservative protein of paramyxoviruses.
Sharova
N K
NK
Kubinova
I
I
Vorkunova
G K
GK
Tumova
B
B
Bukrinskaia
A G
AG
D000956:Antigens, Viral / Q000276:immunology*; D015153:Blotting, Western; D003429:Cross Reactions; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007106:Immune Sera; D010252:Paramyxoviridae / Q000276:immunology*; D014763:Viral Matrix Proteins / Q000276:immunology*
D000956:Antigens, Viral; D007106:Immune Sera; D014763:Viral Matrix Proteins
Konservatizm matriksnogo belka paramiksovirusov.