title: [Taste in healthy subjects. Influence of alcohol and tobacco consumption].
abstract: To define the factors which may affect gustatory function, 42 healthy subjects, without any apparent taste disorder were randomly selected and investigated by electro-gustometry and chemical gustometry. A deterioration in taste discrimination was noted in drinkers in comparison with non-drinkers, both on electro-gustometry, mean threshold (SEM: 88.0 +/- 26.5 versus 47.4 +/- 7.3 microA; p less than 0.05), and also on chemical gustometry (15.1 +/- 2.1 versus 17.4 +/- 0.7; p = 0.05) and also in smokers compared with non smokers (mean of electrical thresholds SEM 104.2 +/- 22.8 versus 38.3 +/- 5.2 microA; p less than 0.01, mean of chemical scores SEM 14.3 +/- 1.1 versus 17.9 +/- 0.9; p less than 0.05). Multivariate analysis demonstrated the influence of the two factors alcohol and tobacco on taste, evaluated by electrogustometry (R2 = 0.36) or chemical gustometry (R2 = 0.28). These results suggest that alcohol and tobacco are liable to influence gustatory function in healthy subjects thereby suggesting that this influence should be taken into account using a corrective factor.
authors.affiliation: Département d'Oto-Rhino-Laryngologie, Centre Hospitalier Intercommunal de Créteil.
authors.forename: G
authors.initials: G
authors.lastname: Lelièvre
authors.forename: J P
authors.initials: JP
authors.lastname: Le Floch
authors.forename: L
authors.initials: L
authors.lastname: Perlemuter
authors.forename: R
authors.initials: R
authors.lastname: Peynègre
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D012044:Regression Analysis; D012907:Smoking / Q000503:physiopathology*; D013649:Taste / Q000187:drug effects* / Q000502:physiology; D013652:Taste Threshold / Q000187:drug effects / Q000502:physiology
vernacular_title: Le Goût chez le sujet sain. Influence de la consommation d'alcool et de tabac.