[Butyrylcholinesterase activity in agricultural workers in seasons when pesticides are not used].
This paper aims at proving the usefulness of determination of butyrylcholinesterase activity (BuChE) out of the spraying season, in workers exposed to pesticides periodically or permanently over a period of several years. A group (I) of 95 agricultural workers periodically exposed to pesticides was examined twice, and another group (II) of 29 permanently exposed workers up to four times. The results were compared with the results for 111 control workers. The mean value for BuChE activity in control workers was x = 1.828 delta pH/30 min (SD = 0.148), and the lower normal value (1.6 delta pH/30 min) was C 6.2. At first examination Group I showed xIa = 1.645 (SD = 0.170), and the lower level of normal value C 38.9. At second examination the respective values were XIb = 1.622 (SD = 0.202) and C 40.1. The values for Group II were XII = 1.680 (SD = 0.199) and C 29.2. The results showed a statistically significant decrease in BuChE activity (p less than 0.01) in Group I as well as in Group II, at both examinations. Comparison of the results for the two exposed groups did not show a statistically significant decrease. The results obtained prove that repeated exposure to pesticides prolongs the time of enzyme BuChE regeneration, thus making determination of BuChE useful even out of spraying season.
Siriski
J
J
Dulizibarić
D
D
Lugumerski
M
M
D000383:Agriculture; D002091:Butyrylcholinesterase / Q000097:blood*; D002802:Cholinesterases / Q000097:blood*; D004781:Environmental Exposure; D006801:Humans; D010575:Pesticides
D010575:Pesticides; D002091:Butyrylcholinesterase; D002802:Cholinesterases
Aktivnost butirilholinesteraze u poljoprivrednih radnika izvan sezone primene pesticida.