[Progress in laboratory tests of connective tissue diseases].
The presence of serum autoantibodies to nuclear antigens (ANA) and other antigens is a hallmark of connective tissue diseases. Antibodies to double-strand DNA were present in high titers in SLE patients. Antibodies to U1RNP correlated with Raynaud's phenomenon and finger erythema in SLE patients. Anticardiolipin antibody was present in 29% of 41 SLE patients. Antibody to Scl-70 was present in 52% of 21 PSS patients. Antibody to Jo-1 was present in patients with PM associated with pulmonary fibrosis. Two of our patients with PM had an autoantibody that precipitated 7SL RNA.
Yamane
K
K
Kato
S
S
Sakauchi
M
M
D001323:Autoantibodies / Q000032:analysis; D002308:Cardiolipins / Q000276:immunology; D002467:Cell Nucleus / Q000276:immunology; D003240:Connective Tissue Diseases / Q000276:immunology*; D004247:DNA / Q000276:immunology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000276:immunology; D009220:Myositis / Q000276:immunology; D012595:Scleroderma, Systemic / Q000276:immunology
D001323:Autoantibodies; D002308:Cardiolipins; D004247:DNA