[Changes in the occurrence of sister chromatid exchange and chromosome aberrations in bone marrow cells of mice after administration of chromium with drinking water].
Through taking into account frequency of sister chromatid metabolisms and chromosome aberrations in bone marrow cells of animals it is demonstrated that under long-term body intake chromium in a wide range of doses can produce mutagenic effect. When assessing chromium mutagenic effect in vivo it is also shown that the test on sister chromatid metabolism is more sensitive than the test on chromosome aberrations in bone marrow cells.
Go'ldina
I R
IR
Saĭchenko
S P
SP
Nadeenko
V G
VG
Diachenko
O Z
OZ
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects* / Q000648:ultrastructure; D002840:Chromates / Q000633:toxicity*; D002869:Chromosome Aberrations; D004305:Dose-Response Relationship, Drug; D004326:Drinking; D051379:Mice; D009154:Mutation; D011192:Potassium Dichromate / Q000008:administration & dosage / Q000633:toxicity*; D012854:Sister Chromatid Exchange / Q000187:drug effects*; D014873:Water Pollutants / Q000633:toxicity*; D014874:Water Pollutants, Chemical / Q000633:toxicity*
D002840:Chromates; D014873:Water Pollutants; D014874:Water Pollutants, Chemical; D011192:Potassium Dichromate
Izmenenie chastoty sestrinskikh khromatidnykh obmenov i khromosom- aberratsiĭ v kletkakh kostnogo mozga mysheĭ, poluchavshikh khrom s pi'tevoĭ vodoĭ.