[Aggregation of isolated myofibrils stimulated by their contraction. II. Aggregation mechanism].
Aggregation of contracted myofibrils was studied as a function of experimental conditions at myofibril contraction. The aggregation rate increased at higher concentrations of suspensions and at increased ionic strength of the medium to achieve the maximum at 0.1 M KCL in the last case. The aggregate sizes grow with an increase of ionic strength and concentration of MgATP and reduce with addition of F-actin. Aggregation of myofibrils develops only in the case of their complete or significant contraction. It was suggested that aggregation is stimulated by dehydration of myofibril at contraction.
Shelud'ko
N S
NS
Korchagin
V P
VP
Kropacheva
I V
IV
Iudin
Iu K
IuK
D000199:Actins / Q000494:pharmacology; D000255:Adenosine Triphosphate / Q000494:pharmacology; D066298:In Vitro Techniques; D009119:Muscle Contraction; D009210:Myofibrils / Q000187:drug effects; D009994:Osmolar Concentration
D000199:Actins; D000255:Adenosine Triphosphate
Agregatsiia izolirovannykh miofibrill, stimuliruemaia ikh sokrashcheniem. II. Mekhanizm agregatsii.