A study of human embryonic cells treated with UV-inactivated measles virus.
Some features of persistent infection were observed in human embryonic fibroblast cells (CLV21K cells) after single treatment with UV-inactivated measles virus. Morphological changes and chromosomal abnormalities were found. In subsequent passages of CLV21K cells, viral antigens were discovered by rosette haemadsorption, immunofluorescence tests and electron microscope or scanning electron microscope studies. No infectious virus was found.
Mazur
N
N
Serum and Vaccine Research Laboratory, Warsaw.
Korbecki
M
M
Zahorska
R
R
D000956:Antigens, Viral / Q000378:metabolism*; D002478:Cells, Cultured; D004622:Embryo, Mammalian; D005347:Fibroblasts / Q000166:cytology / Q000382:microbiology*; D006801:Humans; D008459:Measles virus / Q000276:immunology / Q000472:pathogenicity* / Q000528:radiation effects; D009132:Muscles / Q000166:cytology; D012867:Skin / Q000166:cytology; D014466:Ultraviolet Rays
D000956:Antigens, Viral