title: [Evaluation of the Coulter STKR differential histogram and the Coulter VCS formula analysis: a strategy of joint utilization].
abstract: Coulter STKR is an haematological analyser providing a histogram differential analysis with interpretative report (IR). Coulter VCS is a flow cytometer providing a leucocyte five-part differential. Both instruments include a software for flagging abnormal differentials. They were evaluated in an hospital with numerous haematological and Pediatric patients. By using the same criteria as the analysers, the frequency of abnormalities found in 638 samples by the optical method was 42%. STKR histogram differential, with IR and monocytes lab action limits, resulted in a 53% review rate with a false negative percentage of 2.2%. VCS analysis resulted in a 52% review rate with a false negative percentage of 0.8%. Association of both instruments, the VCS analysis being performed only on samples having given non IR alarms, resulted in a lower false negative percentage (0.5%). In a population such as ours, with an important part of pathological conditions, these results may be considered satisfactory, both regarding the safety and the review rate.
authors.affiliation: Laboratoire d'Hématologie, Hôtel-Dieu, Centre Hospitalier Universitaire, Nantes, France.
authors.forename: R
authors.initials: R
authors.lastname: Garand
authors.forename: F
authors.initials: F
authors.lastname: Accard
mesh_terms: D001322:Autoanalysis; D005069:Evaluation Studies as Topic; D005188:False Negative Reactions; D006098:Granulocytes / Q000166:cytology; D006801:Humans; D007958:Leukocyte Count / Q000295:instrumentation*; D008214:Lymphocytes / Q000166:cytology; D009000:Monocytes / Q000166:cytology
vernacular_title: Evaluation de l'histogramme différentiel Coulter STKR et de l'analyseur a formules Coulter VCS: une stratégie d'utilisation conjointe.