title: Advantages of treatment with Reprimun in sarcoidosis.
abstract: Favourable results were obtained by treatment with Reprimun alone or in association with low doses of Prednisone in 112 patients with sarcoidosis (59% with active sarcoidosis and 33% failures of a previous corticotherapy). Treatments were applied during 3-6 series each one of 6 weeks at intervals of 2 weeks between series. In comparison with the classical corticotherapy, treatment with Reprimun has better results, namely: absence of any major adverse reactions; reduction of the treatment period to 6-12 months (3-6 series); 95% lasting remissions in the sarcoidoses with initial treatment and 78% remissions in the case of failures of a previous corticotherapy.
authors.affiliation: Tuberculosis Research Institute, Bucharest, Romania.
authors.forename: E
authors.initials: E
authors.lastname: Păunescu
authors.forename: C
authors.initials: C
authors.lastname: Didilescu
authors.forename: F
authors.initials: F
authors.lastname: Mihălţan
authors.forename: S
authors.initials: S
authors.lastname: Udrea
authors.forename: A
authors.initials: A
authors.lastname: Serbescu
authors.forename: M
authors.initials: M
authors.lastname: Dănălache-Dumitrescu
authors.forename: M
authors.initials: M
authors.lastname: Smărăndache
authors.forename: M
authors.initials: M
authors.lastname: Stoinescu
authors.forename: C
authors.initials: C
authors.lastname: Zaharescu
authors.forename: A
authors.initials: A
authors.lastname: Petre
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000188:drug therapy*; D008297:Male; D008477:Mediastinal Diseases / Q000188:drug therapy*; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use*; D012074:Remission Induction; D012294:Rifamycins / Q000627:therapeutic use*; D012507:Sarcoidosis / Q000188:drug therapy*
chemical_list: D012294:Rifamycins; C062637:Reprimun; D011241:Prednisone