[Diagnostic value of radioimmunological analysis of CA-19-9 in the blood serum in cancer of the pancreas].
The CA 19-9 antigen content was studied in 163 patients with pancreatic diseases by radioimmunologic method with the use of commercial test-kits ("Sorin", France). Pancreatitis was diagnosed in 67 patients, pancreatic cancer--in 23, cancer of the major duodenal papilla (MDP)--in 14, malignant neoplasms of the stomach, colon and rectum, liver--in 58. All the results were verified by morphologic studies. The control group included 22 donors. In patients with pancreatic cancer, the considerable increase in the CA 19-9 level was noted when compared with antigen content in the norm and in the other patients examined. The indices of CA 19-9 in pancreatitis don't differ from the normal ones. In MDP cancer and malignant tumours of other location with tumour invasion into the pancreas, the serum CA 19-9 level was increased.
Putseva
N M
NM
Chebotareva
E D
ED
Chernyĭ
V A
VA
Tashchiev
R K
RK
D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis*; D014408:Biomarkers, Tumor / Q000097:blood; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D010195:Pancreatitis / Q000097:blood / Q000175:diagnosis / Q000276:immunology; D011863:Radioimmunoassay
D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor
Diagnosticheskaia znachimos't radioimmunologicheskogo opredeleniia CA 19-9 v syvorotke krovi pri rake podzheludochnoĭ zhelezy.