title: [Problem of typological differentiation of the defect in symptom-poor schizophrenia (clinico-genetic correlations)].
abstract: The clinico-genealogical method with the use of a genetic-mathematic analysis was applied to examine 85 probands with pure-symptoms schizophrenia (221 relations of grade I kinship). Schizophrenia with the defect of the simple deficiency type was established to be genetically, similar to schizophrenia with a psychopath-like defect characterized by veschroben. Different types of familial predisposition by the type of schizophrenia+ and by the spectrum of psychopathies were found to correspond to the studied variants of pure-symptoms schizophrenia. These correlations were confirmed by the data of the genetic-correlation analysis. It is assumed that determination of the typological differences in the defect structure in pure-symptoms schizophrenia is under the control of constitutional and genetic factors.
authors.forename: L L
authors.initials: LL
authors.lastname: Lu'kianova
mesh_terms: D000328:Adult; D002648:Child; D003937:Diagnosis, Differential; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000235:genetics* / Q000523:psychology; D012559:Schizophrenia / Q000145:classification* / Q000175:diagnosis / Q000235:genetics; D012569:Schizotypal Personality Disorder / Q000145:classification* / Q000175:diagnosis / Q000235:genetics
vernacular_title: K probleme tipologicheskoĭ differentsiatsii defekta pri bednoĭ simptomami shizofrenii (kliniko-geneticheskie korreliatsii).