Treating chancroid: summary of studies in southern Africa.
Recent studies undertaken in southern Africa and elsewhere indicate that many short or single dose treatments are available to treat chancroid. Erythromycin 500 mg three times a day for five days, ciprofloxacin 500 mg, sulphamethopyrazine 800 mg and trimethoprim 1000 mg or sulphametrole 3200 mg and trimethoprim 640 mg as single oral doses, or ceftriaxone 250 mg as a single intramuscular injection are all effective in treating the disease. The widespread use of these regimens largely depends on the accuracy of diagnosis, susceptibilities of local Haemophilus ducreyi isolates to antimicrobials, and financial considerations.
Ballard
R C
RC
South African Medical Research Council, School of Pathology, University of the Witwatersrand.
Duncan
M O
MO
Fehler
H G
HG
Dangor
Y
Y
Exposto
F L
FL
Latif
A S
AS
D042462:4-Quinolones; D000353:Africa, Southern; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D002602:Chancroid / Q000188:drug therapy*; D004917:Erythromycin / Q000627:therapeutic use; D006801:Humans; D013449:Sulfonamides / Q000627:therapeutic use; D014295:Trimethoprim / Q000627:therapeutic use
D042462:4-Quinolones; D000890:Anti-Infective Agents; D013449:Sulfonamides; D004917:Erythromycin; D014295:Trimethoprim