Age-associated changes in parathyroid hormone in black males.
To examine changes in calcium metabolism related to aging in blacks and caucasians, we measured serum mid-molecule parathyroid hormone (PTH), total and ionised calcium in 83 black and 47 caucasian healthy males aged 31-77 yrs. Age and race were without effect on total or ionised calcium. PTH levels increased significantly (P less than 0.03) with age in black but not caucasian subjects. These results demonstrate an aging-associated increase in circulating PTH in blacks and are consistent with other data from our laboratory which suggest that PTH may be involved in the development of salt-sensitive hypertension in blacks.
Zemel
P
P
Division of Endocrinology and Hypertension, Wayne State University School of Medicine, Detroit, MI 48202.
Gualdoni
S
S
Zemel
M B
MB
Allison
T
T
Sowers
J R
JR
D000328:Adult; D000368:Aged; D000375:Aging / Q000378:metabolism*; D044383:Black People; D006801:Humans; D008297:Male; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000378:metabolism*; D012727:Sex Characteristics; D044465:White People
D010281:Parathyroid Hormone