[Prolonged myocardial ischemia after the high-dose dipyridamole test].
The intravenous dipyridamole test is considered a safe procedure with a very low incidence of severe cardiac effects and is routinely used in the diagnosis and prognosis of coronary artery disease. We report the case of a 63-year-old female with negative exercise stress test who developed prolonged and extensive myocardial ischemia after the high-dose intravenous dipyridamole echocardiography test. Aminophylline and nitroglycerin were employed but were ineffective and the patient was successfully treated with systemic thrombolysis. At coronary angiography, 48 hours later, a 50% stenosis in the proximal LAD was documented. We stress that high-dose intravenous dipyridamole can induce a severe ischemic response whose occurrence is unpredictable according to the pre-test clinical features.
Arfiero
S
S
Divisione Clinicizzata di Cardiologia, Ospedale Civile di Vicenza, Università degli Studi di Verona.
La Vecchia
L
L
Bedogni
F
F
Vincenzi
M
M
D003327:Coronary Disease / Q000139:chemically induced* / Q000503:physiopathology; D004176:Dipyridamole / Q000008:administration & dosage / Q000009:adverse effects*; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008875:Middle Aged
D004176:Dipyridamole
Ischemia miocardica prolungata dopo test al dipiridamolo ad alta dose.