title: [The value of large pressure-relieving trepanation in treatment of refractory brain edema. Animal experiment studies, initial clinical results].
abstract: Our animal-experimental results obtained in large-area pressure-relieving trepanation after severe craniocerebral traumas with intracranial pressure measuring and oxygen tissue pressure measuring in the brain were compared on the basis of 19 patients operated on in this way. In these operations we followed the achieved principles according to which, if possible at a relatively early time and on large areas, a fronto-temporo-parietal trepanation on both sides should be carried out, in order to make the shifting to the right in the pressure-volume curve sufficiently large, to avoid or remove the squeezing of the brain stem, and to keep the pressure ischaemisation of the cerebral tissue low.
authors.affiliation: Neurochirurgische Abteilung, Klinik und Poliklinik für Chirurgie, Martin Luther-Universität Halle-Wittenberg.
authors.forename: W
authors.initials: W
authors.lastname: Burkert
authors.forename: H
authors.initials: H
authors.lastname: Plaumann
mesh_terms: D000818:Animals; D001925:Brain Damage, Chronic / Q000503:physiopathology; D001929:Brain Edema / Q000503:physiopathology / Q000601:surgery*; D001930:Brain Injuries / Q000503:physiopathology / Q000601:surgery*; D004285:Dogs; D015600:Glasgow Coma Scale; D006801:Humans; D007427:Intracranial Pressure / Q000502:physiology*; D011183:Postoperative Complications / Q000503:physiopathology; D014207:Trephining / Q000379:methods*
vernacular_title: Der Wert der grossen druckentlastenden Trepanation beim therapieresistenten Hirnödem. Tierexperimentelle Untersuchungen, erste klinische Ergebnisse.