title: [Antibodies against HTLV-1 in patients undergoing multiple transfusions].
abstract: HTLV-1 is a retrovirus which causes adult T cell leukemia and is transmitted through contaminated blood products. Patients who have received multiple transfusions are therefore at high risk of HTLV-1 infection. Since it has been postulated that 0.5% of Spanish blood donors present HTLV-1 antibodies, we decided to investigate the presence of these in 154 polytransfused patients in Barcelona. We could not demonstrate the presence of HTLV-1 infection in any of the patients although six of them gave positive ELISA results repeatedly. The validity of tests previously used for the detection of HTLV-1 antibodies is discussed and multicentric studies with a wider population sample are suggested in order to establish the real incidence of HTLV-1 infection in our community.
authors.forename: V
authors.initials: V
authors.lastname: Soriano
authors.forename: M
authors.initials: M
authors.lastname: Pauplana
authors.forename: A
authors.initials: A
authors.lastname: Ribera
authors.forename: J
authors.initials: J
authors.lastname: Tor
authors.forename: M
authors.initials: M
authors.lastname: Foz
mesh_terms: D001803:Blood Transfusion; D015481:HTLV-I Antibodies / Q000032:analysis*; D015490:HTLV-I Infections / Q000635:transmission*; D006801:Humans; D012189:Retrospective Studies
chemical_list: D015481:HTLV-I Antibodies
vernacular_title: Investigación de anticuerpos frente al HTLV-1 en pacientes politransfundidos.