title: Experimental production of new zymodemes of Entamoeba histolytica supports the hypothesis of genetic exchange.
abstract: By mixing in culture zymodemes of Entamoeba histolytica, clones showing a different pattern from the 2 parents have been obtained on 3 occasions. Two new zymodemes (XI alpha- and XXI) have thus been produced, which belong to the third generation of a family of E. histolytica zymodemes apparently obtained by genetic exchange. A hypothesis for the molecular basis of those exchanges is discussed. We report also the observation of probable mutation.
authors.affiliation: Department of Medical Protozoology, London School of Hygiene and Tropical Medicine, UK.
authors.forename: D
authors.initials: D
authors.lastname: Blanc
authors.forename: R
authors.initials: R
authors.lastname: Nicholls
authors.forename: P G
authors.initials: PG
authors.lastname: Sargeaunt
mesh_terms: D000818:Animals; D003470:Culture Media; D004586:Electrophoresis; D004747:Entamoeba / Q000201:enzymology / Q000235:genetics* / Q000302:isolation & purification; D007527:Isoenzymes / Q000032:analysis / Q000235:genetics*; D013045:Species Specificity
chemical_list: D003470:Culture Media; D007527:Isoenzymes