[Lysozyme activity in the blood serum and lysosomes and lysosomal supernatant of neutrophils in patients with psoriasis treated by the PUVA method].
The determinations of the activity of lysozyme in the serum, lysosomes and lysosomal supernatant of neutrophil granulocytes were done in 33 patients with generalized psoriasis and in 19 healthy controls. A decrease of lysozyme activity was demonstrated in the serum, lysosomes and lysosomal supernatant in the patients. During treatment by the PUVA method this activity rose gradually above the values in the control group. Systematic determination of lysozyme activity may help in monitoring of treatment progress.
Kaszuba
A
A
Czarnecki
M
M
Ruszczak
Z
Z
Bienias
L
L
Kozłowska
M
M
D000328:Adult; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008247:Lysosomes / Q000201:enzymology*; D008297:Male; D009113:Muramidase / Q000097:blood*; D009504:Neutrophils / Q000201:enzymology* / Q000648:ultrastructure; D011701:PUVA Therapy; D011565:Psoriasis / Q000097:blood* / Q000188:drug therapy; D012016:Reference Values
D009113:Muramidase
Aktywność lizozymu w surowicy krwi, w lizosomach i w nadsaczu lizosomalnym granulocytów obojetnochłonnych u chorych na łuszczyce leczonych metoda PUVA.