[Reactivity of LK-1 monoclonal antibodies with human hematopoietic cells].
A murine monoclonal antibody LK-1 reacting with the common leukocytic antigen gp 95 was prepared by means of standard hybrid technology. This antigen was found in wider distribution on various morphologic types of human blood cells of the monocytic, granulocytic, thrombocytic, erythroid and lymphoid series (with the exception of some B lymphocytes). Furthermore, the monoclonal antibody reacted with the antigen occurring on leukaemic cells of patients with AML, CML, AMMoL, ALL and AMoL and reacted with cells of some human cell lines as well.
Koubek
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D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000937:Antigen-Antibody Reactions; D000943:Antigens, Differentiation / Q000276:immunology*; D006412:Hematopoietic Stem Cells / Q000276:immunology*; D006801:Humans; D007938:Leukemia / Q000276:immunology; D051379:Mice
D000911:Antibodies, Monoclonal; D000943:Antigens, Differentiation
Reaktivita LK-1 monoklonální protilátky s lidskými hematopoetickými bunkami.