Low platelet monoamine oxidase activity in borderline personality disorder.
Platelet monoamine oxidase (MAO) activity was significantly lower in nonpsychotic, nonorganic, unmedicated male inpatients with DSM-III-R borderline personality disorder (BPD) than in nonpsychiatric controls. Patients with BPD who also met DSM-III-R criteria for antisocial personality disorder had significantly lower MAO activity than those with BPD alone. Low MAO activity in this sample did not appear to be related to the comorbid presence of major depressive disorder or a history of substance abuse.
Yehuda
R
R
University of Connecticut Health Center, Farmington 06516.
Southwick
S M
SM
Edell
W S
WS
Giller
E L
EL
D000293:Adolescent; D000328:Adult; D000987:Antisocial Personality Disorder / Q000201:enzymology; D001008:Anxiety Disorders / Q000201:enzymology; D001792:Blood Platelets / Q000201:enzymology*; D001883:Borderline Personality Disorder / Q000175:diagnosis / Q000201:enzymology*; D003866:Depressive Disorder / Q000201:enzymology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008995:Monoamine Oxidase / Q000097:blood*; D010556:Personality Tests; D019966:Substance-Related Disorders / Q000201:enzymology
D008995:Monoamine Oxidase