[Lyophilized homologous bone grafts in middle ear surgery: new perspectives].
The authors share their experience of the use of allografts in the reconstruction of the tympano-ossicular chain. The implants were cut from the cortical substance of the long bone in patients deceased for a maximum of six hours; the donors were tested for syphilis, hepatitis, AIDS, systemic diseases or a neoplasm. These bone allografts were cut to size, degreased, demineralized, frozen and then lyophilized in order to be presented to the surgeon in a sterile container (Bone Bank). The implants were all tolerated well. The anatomical results were satisfactory. Optical microscopic studies showed that the implant was: a) covered with mucosa, b) full of osteoblasts and c) the site of a bone neoformation. Experimental research is currently underway in order to perfect the implant preparation methodology.
Maisin
J P
JP
Munting
E
E
Delloye
C
C
Gersdorff
M
M
D016025:Bone Transplantation; D002781:Cholesteatoma / Q000601:surgery*; D002908:Chronic Disease; D005612:Freeze Drying; D006801:Humans; D010033:Otitis Media / Q000601:surgery*; D012086:Reoperation; D014433:Tympanoplasty
Les homogreffes osseuses lyophilisées dans la chirurgie de l'oreille moyenne: nouvelles perspectives.