title: [Sperm count and seminal biochemistry of high altitude inhabitants and patients with chronic altitude sickness].
abstract: Semen analysis has been studied in 9 healthy adult males from sea level (150 m), age 19-32 years old and 15 healthy males from high altitude (NA), 9 from Cerro de Pasco (4,300 m) and 6 from Morococha (4,540 m), ages 19-45 years old. Five patients with chronic mountain sickness (MMC), whose ages ranged from 23 to 52 years old were also studied. The volume and motility were similar in NA and MMC, however both were below than in sea level subjects, but still in the normal range; the number of spermatozoa per 1 ml was lower at sea level than in NA and MMC, although the total number was higher at sea level due to the higher semen volume. Fructose at sea level was 356 +/- 53 mg/100 ml (mean +/- S.E.) which is similar to NA 237 +/- 45 whereas a MMC was significantly lower, 142 +/- 60. Citric acid was lower at sea level than in NA and MMC. Na, K and Cl, were similar among the three groups. The lower concentration of fructose in MMC parallels the decreased testicular function already found in these groups. However it is worthy to point out that the fertility is preserved in all the groups. The normal reproductive function in MMC is against the concept that this process occurs as a consequence of environmental disadaptation.
authors.affiliation: Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima.
authors.forename: M A
authors.initials: MA
authors.lastname: García-Hjarles
mesh_terms: D000328:Adult; D000531:Altitude; D000532:Altitude Sickness / Q000503:physiopathology*; D002951:Citrates / Q000378:metabolism; D019343:Citric Acid; D005632:Fructose / Q000378:metabolism; D006801:Humans; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012098:Reproduction; D012661:Semen / Q000378:metabolism*; D013076:Sperm Count; D013081:Sperm Motility
chemical_list: D002951:Citrates; D019343:Citric Acid; D005632:Fructose
vernacular_title: Espermatograma y bioquímica seminal de nativos de altura y pacientes con mal de montaña crónica.