title: [HLA antigen frequencies in patients with autosomal dominant polycystic kidney degeneration].
abstract: 20 non-related patients suffering from autosomal dominantly polycystic renal disease were HLA-A, -B, -C and -DR typified and the HLA frequencies were compared with the normal population. Tissue typing was performed using the lymphocytotoxicity test using 180 well-characterized test sera. In contrast to the literature no significant differences were found. However, the value of erythrocytic phosphoglycolate-phosphatase-phenotyping should be checked in the genetic control and consultation.
authors.affiliation: Klinik und Poliklinik für Innere Medizin, Bereiches Medizin, Ernst-Mortiz-Arndt-Universität Greifswald.
authors.forename: J
authors.initials: J
authors.lastname: Spengler
authors.forename: S
authors.initials: S
authors.lastname: Wegener
authors.forename: H
authors.initials: H
authors.lastname: Schüler
authors.forename: G
authors.initials: G
authors.lastname: Kraatz
mesh_terms: D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D005787:Gene Frequency; D005799:Genes, Dominant; D006680:HLA Antigens / Q000235:genetics*; D015234:HLA-A Antigens / Q000235:genetics; D015235:HLA-B Antigens / Q000235:genetics; D015236:HLA-C Antigens / Q000235:genetics; D006684:HLA-DR Antigens / Q000235:genetics; D006801:Humans; D007690:Polycystic Kidney Diseases / Q000235:genetics*; D012307:Risk Factors
chemical_list: D006680:HLA Antigens; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D015236:HLA-C Antigens; D006684:HLA-DR Antigens
vernacular_title: HLA-Antigenfrequenzen bei Patienten mit autosomal-dominanter polyzystischer Nierendegeneration.