[The role of homeostatic function of the kidneys in the development of hyperuricemia].
The content of uric acid in blood plasma has been determined and its relation with the homeostatic renal function has been studied in CHD and hypertensive patients. The attenuation of renal filtration processes has been revealed in a half of the 117 patients. The CHD patients have showed a significant relation between the levels of uric acid and protein in blood. There is an immediate correlation between the uric acid content and alpha 2-globulins in patients with CHD and hyperuricemia. It has been suggested that the development of hyperuricemia in CHD patients is dut to the mechanism of disturbances in binding of uric acid to transport blood proteins.
Karvé
M D
MD
Shamarin
V M
VM
Vinogradova
I V
IV
Kiseleva
N S
NS
Ankhimiuk
O N
ON
D000328:Adult; D000368:Aged; D001798:Blood Proteins / Q000032:analysis; D003327:Coronary Disease / Q000097:blood / Q000503:physiopathology; D003404:Creatinine / Q000097:blood; D006706:Homeostasis / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000503:physiopathology; D007668:Kidney / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D014508:Urea / Q000097:blood; D014527:Uric Acid / Q000097:blood*
D001798:Blood Proteins; D014527:Uric Acid; D014508:Urea; D003404:Creatinine
Rol' gomeostaticheskoĭ funktsii pochek v razvitii giperurikemii.