[A new marker in oncology. Assay of gangliosides bound to sialic acid].
Gangliosides are released from cells proliferating in serum and can be assayed by a LASA method. The authors report the assay method for sialic acid bound exclusively to glycosphingolipids (GASA method). They study the reliability and discuss the preliminary factors concerning this upper respiratory tract squamous cell marker.
Pignat
J C
JC
Service d'ORL, Hôpital de la Croix Rousse, Lyon.
Portoukalian
M
M
Poupart
M
M
Haguenauer
J P
JP
Richard
M
M
D014408:Biomarkers, Tumor / Q000097:blood*; D002272:Carcinoembryonic Antigen / Q000276:immunology; D005188:False Negative Reactions; D005679:G(M3) Ganglioside / Q000097:blood*; D005732:Gangliosides / Q000032:analysis / Q000097:blood*; D006801:Humans; D008722:Methods; D019158:N-Acetylneuraminic Acid; D010039:Otorhinolaryngologic Neoplasms / Q000097:blood*; D012794:Sialic Acids / Q000378:metabolism*
D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D005679:G(M3) Ganglioside; D005732:Gangliosides; D012794:Sialic Acids; D019158:N-Acetylneuraminic Acid
Un nouveau marqueur en cancérologie. Le dosage des gangliosides liés à l'acide sialique.