[Selected immunologic parameters and infections in children in over 1 year after completion of the treatment of acute lymphoblastic leukemia].
An analysis of infection incidence within one year after completion of the treatment for the acute lymphoblastic leukemia was performed in the group of 24 children. Infections incidence was related to the selected immunological parameters, mainly T4 and T8 lymphocyte subpopulations assayed with monoclonal antibodies. T4/T8 cells ratio (Ix) was determined. It was found that moderate decrease in the total lymphocyte count and Ix exist in children one year after completion of the treatment. This index is more significantly lower in children with more frequent infections while the absolute numbers of T4 and T8 lymphocytes are relatively increased. The obtained results suggest that no significant immunosuppression is observed in children affecting the number and the course of infections.
Rytwiński
K
K
Sońta-Jakimczyk
D
D
Sroczyńska
M
M
Wójcik
Z
Z
Dzielicki
J
J
D001424:Bacterial Infections / Q000209:etiology*; D002648:Child; D003176:Complement C3 / Q000276:immunology*; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology; D007958:Leukocyte Count; D009894:Opportunistic Infections / Q000209:etiology*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000276:immunology* / Q000628:therapy; D013601:T-Lymphocytes / Q000276:immunology*; D013997:Time Factors; D014168:Transferrin / Q000032:analysis*
D003176:Complement C3; D014168:Transferrin
Wybrane parametry immunologiczne a zakazenia u dzieci w okresie ponad jednego roku od zakończenia leczenia ostrej białaczki limfoblastycznej.