[Generalized morphea-like progressive systemic sclerosis with anticentromere antibodies and eosinophilic cellulitis].
A 67-year-old woman without any history of exposure to organic solvents suffered from Raynaud's phenomenon, sclerodactylia, contracture of finger joints, diffuse pigmentation, pulmonary fibrosis, and generalized morphea-like eruptions on the trunk; she was diagnosed as generalized morphea-like progressive systemic sclerosis. She had a high titer of anticentromere antibody in her serum without any symptoms of CREST syndrome. She also had eosinophilic cellulitis on her extremities, which subsided within 6 months, and seemed to be due to a hypersensitivity reaction to mosquito bites. The occurrence of these two diseases together in our case may suggest some similarities in their pathogenesis.
Sasaki
T
T
Nakajima
H
H
Kameda
Y
Y
D000368:Aged; D001323:Autoantibodies / Q000032:analysis*; D002481:Cellulitis / Q000150:complications*; D002503:Centromere / Q000276:immunology*; D002875:Chromosomes / Q000276:immunology*; D004802:Eosinophilia / Q000150:complications*; D005260:Female; D006801:Humans; D012594:Scleroderma, Localized / Q000473:pathology; D012595:Scleroderma, Systemic / Q000150:complications* / Q000276:immunology; D012867:Skin / Q000473:pathology
D001323:Autoantibodies