title: Antibiotic susceptibility of rickettsia and treatment of rickettsioses.
abstract: The author describes the in vitro data for antibiotic susceptibility of Rickettsia and Coxiella burnetti. Tetracyclines are still the first antibiotic choice in spotted fevers, typhus and Q fever. In spotted fever a shortened treatment is suggested and the place of macrolide antibiotics, such as Josamycin, in treating children may be evaluated. In Q fever, according to the new biological data, an association of tetracyclines and Rifampin or Quinolones is suggested.
authors.affiliation: Centre national de reference des rickettsioses, WHO collaborative center for diagnosis and research CHU la Timone, Marseille, France.
authors.forename: D
authors.initials: D
authors.lastname: Raoult
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003381:Coxiella / Q000187:drug effects; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D011247:Pregnancy; D011778:Q Fever / Q000188:drug therapy; D012281:Rickettsia / Q000187:drug effects*; D012282:Rickettsia Infections / Q000188:drug therapy*; D012373:Rocky Mountain Spotted Fever / Q000188:drug therapy; D014437:Typhus, Endemic Flea-Borne / Q000188:drug therapy; D014438:Typhus, Epidemic Louse-Borne / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents