Microvascular circulation of the ascending colon in horses.
Microvascular circulation of the ascending colon in healthy horses was studied using microangiography, light microscopy, and scanning electron microscopy. The pelvic flexure with 30 cm of ventral and dorsal colon attached was removed from 14 adult horses immediately after horses were euthanatized. The lumen was flushed with warm water, and this section of the ascending colon was placed in a 37-C bath of isotonic NaCl. In sections from 8 horses, colic vessels were perfused with a radio-opaque medium for microangiography. After angiographic evaluation, tissue sections were prepared for light microscopic observation, using standard histologic methods. In sections from 6 horses, injection replicas were made by perfusing the vessels with 2 types of plastics. The results of microangiography, light microscopy, and scanning electron microscopy of vascular replicas were correlated, providing a comprehensive documentation of the microvasculature of the ascending colon at the pelvic flexure. Arteries branched from mesenteric colic vessels approximately every 2 cm toward the colonic tissue. Immediately after branching, arterial vessels formed an anastomotic plexus, the colonic rete. However, each branch from the colic vessel eventually continued into the colonic tissue. A second set of vessels originated from the colonic tissue. A second set of vessels originated from the colonic rete and supplied the mesenteric lymph nodes. Arterial vessels penetrated the tunica muscularis into the submucosa 3 to 4 cm toward the antimesenteric border forming a submucosal vascular network. From the submucosal arterioles, branching took place at right angles to supply the mucosal capillaries. Capillaries surrounded the colonic glands and anastomosed at the luminal surface, forming a superficial luminal honeycomb-appearing vascular plexus.(ABSTRACT TRUNCATED AT 250 WORDS)
Snyder
J R
JR
Department of Surgery, School of Veterinary Medicine, University of California, Davis 95616.
Tyler
W S
WS
Pascoe
J R
JR
Olander
H J
HJ
Bleifer
D R
DR
Hinds
D M
DM
Neves
J W
JW
D000792:Angiography / Q000662:veterinary; D000818:Animals; D003106:Colon / Q000098:blood supply*; D005260:Female; D006736:Horses / Q000502:physiology*; D007413:Intestinal Mucosa / Q000098:blood supply*; D008297:Male; D008833:Microcirculation; D008855:Microscopy, Electron, Scanning; D015424:Reperfusion / Q000662:veterinary