title: Genetic polymorphism of C3 in the Veneto population, Italy.
abstract: The distribution of C3 phenotypes in the population of Veneto was investigated by electrophoresis on agarose gel. In our sample (n = 810) the three common phenotypes C3 SS, C3 FF and C3 FS and a further phenotype, C3 S-VF, were observed. The following gene frequencies could be calculated: C3S = 0.8068, C3F = 0.1926 and C3V = 0.0006. These frequencies have been compared with those found in other populations. The analysis of 21 mother-child pairs was in agreement with an autosomal codominant inheritance.
authors.affiliation: Istituto di Medicina Legale dell'Università di Padova, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Crestani
authors.forename: L
authors.initials: L
authors.lastname: Caenazzo
authors.forename: P
authors.initials: P
authors.lastname: Cortivo
authors.forename: C
authors.initials: C
authors.lastname: Scorretti
authors.forename: C
authors.initials: C
authors.lastname: Caenazzo
mesh_terms: D003176:Complement C3 / Q000235:genetics*; D005787:Gene Frequency / Q000235:genetics; D005828:Genetics, Population; D006801:Humans; D007558:Italy; D010641:Phenotype; D011110:Polymorphism, Genetic
chemical_list: D003176:Complement C3