title: [A systemic model of the reproductive death of mammalian cells. The effect of radiation dose rate and fractionation].
abstract: On the basis of the previously developed systemic model a study was made of the effect of dose rate on the survival of mammalian cells, RBE of small doses of heavy ions, and fractionation of radiation. There was a good agreement between theoretical and experimental results. The calculations showed that D10 (10% survival dose) is a function of dose rate P even for such ions as helium and boron which, however, exhibited an insignificant dependence of D10 on P (within the range from (10(-1) to 1 cGy/min). The influence of repair and the rate of cell division on RBE of radiation was determined.
authors.forename: G M
authors.initials: GM
authors.lastname: Obaturov
authors.forename: A S
authors.initials: AS
authors.lastname: Filimonov
mesh_terms: D000818:Animals; D001895:Boron; D002460:Cell Line; D002470:Cell Survival / Q000528:radiation effects*; D006371:Helium; D007477:Ions; D008433:Mathematics; D051379:Mice; D008954:Models, Biological; D011829:Radiation Dosage; D012062:Relative Biological Effectiveness
chemical_list: D007477:Ions; D006371:Helium; D001895:Boron
vernacular_title: Sistemnaia model' reproduktivnoĭ gibeli kletok mlekopitaiushchikh. Vliianie moshchnosti dozy i fraktsionnirovaniia oblucheniia.