title: [Quantitative changes in mitochondrial membrane structure of leukemic cells in children with acute leukemia].
abstract: The quantitative changes of mitochondrial membrane of AL cells were studied by morphometric technique under electron microscope. We found that the delta sM was 25.0% more increased and the delta mM was 18.0% more decreased in AL than in the controls. The extent of changed of delta mM in C-ALL and N-ALL was much greater than that in T-ALL. We also found that the changing extent of delta mM in AL is related with long term disease-free survival. During the period of inductive therapy, observation on the dynamic changes of delta mM may provide a useful information for predicting the therapeutic effects and the therapeutic scheme individually.
authors.forename: G X
authors.initials: GX
authors.lastname: Sun
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D015470:Leukemia, Myeloid, Acute / Q000473:pathology*; D008214:Lymphocytes / Q000648:ultrastructure; D008297:Male; D008928:Mitochondria / Q000648:ultrastructure*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000473:pathology*; D011379:Prognosis