title: The role of acupuncture in asthma: changes in airways dynamics and LTC4 induced LAI.
abstract: A cohort of nine extrinsic asthma patients were treated by means of acupuncture. Patients were followed up for changes in medical treatment, spirometry, skin reactivity to immediate type reactions, total serum IgE levels and reactivity of their leukocytes to leukotriene C4 challenge (LTC4 induced leukocyte adherence inhibition (LAI) assay). Our results show that after acupuncture, treated patients were able to reduce bronchodilator and taper completely corticosteroid therapy. No change in skin reactivity or in IgE levels were noted. However, acupuncture treatment was able to negate, in 66.6%, the positive LTC4 induced responses.
authors.affiliation: Pulmonary Unit, Kaplan Hospital, Rehovot.
authors.forename: M
authors.initials: M
authors.lastname: Sternfeld
authors.forename: A
authors.initials: A
authors.lastname: Fink
authors.forename: Z
authors.initials: Z
authors.lastname: Bentwich
authors.forename: A
authors.initials: A
authors.lastname: Eliraz
mesh_terms: D015670:Acupuncture Therapy / Q000379:methods*; D000328:Adult; D000403:Airway Resistance; D001249:Asthma / Q000276:immunology / Q000503:physiopathology / Q000628:therapy*; D001993:Bronchodilator Agents / Q000008:administration & dosage; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007957:Leukocyte Adherence Inhibition Test; D007962:Leukocytes / Q000276:immunology*; D008297:Male; D012129:Respiratory Function Tests; D013189:SRS-A / Q000276:immunology; D012882:Skin Tests
chemical_list: D001993:Bronchodilator Agents; D013189:SRS-A; D007073:Immunoglobulin E