[The influence of dose of transfusion and component of blood on the incidence of post-transfusion hepatitis].
Two thousand five hundred ninety-six consecutive patients who received blood transfusion for the first time within one week and had no liver dysfunction before transfusion had been selected from 8637 patients who received blood transfusion at the hospital between 1982 and 1987. The influence of dose, components of transfused blood and sex, age of recipients on the incidence of post-transfusion hepatitis was investigated. The rate of development of hepatitis depended on the dose of transfusion, not on sex and age of recipients. The rate of development of hepatitis raised as number of transfused blood increased without limiting point to 100%. The carrier rate of healthy population of non-A, non-B hepatitis virus was estimated 1.39%. Stored blood, concentrated red blood cell and fresh blood are high risk components and fresh frozen plasma was low risk component.
Takano
S
S
Omata
M
M
Ohto
M
M
Satomura
Y
Y
D006505:Hepatitis / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D007564:Japan; D012307:Risk Factors; D065227:Transfusion Reaction