[Drug interactions during storage of mixtures of the antacid group. II. Effect of temperature on the formation of hydrotalcite in neutralizing suspensions].
Eight antacid mixtures were stored for 110 days at 25 degrees C, 35 degrees C and 45 degrees C in the form of suspensions in water. Changes in pH were followed, and the structural changes in suspension components were studied by X-ray analysis. It has been stated that formation of hydrotalcite, the product od interaction of the mixture components depends mainly on the kind and ratio of the suspension reactants, and only to a little degree on the storage temperature.
Pawlaczyk
J
J
Lutka
A
A
D000536:Aluminum Hydroxide / Q000008:administration & dosage / Q000138:chemical synthesis* / Q000494:pharmacology*; D000863:Antacids; D002254:Carbonates / Q000008:administration & dosage / Q000494:pharmacology*; D004347:Drug Interactions; D004355:Drug Stability; D004356:Drug Storage; D006863:Hydrogen-Ion Concentration; D008274:Magnesium / Q000494:pharmacology*; D008276:Magnesium Hydroxide / Q000008:administration & dosage / Q000138:chemical synthesis* / Q000494:pharmacology*; D013535:Suspensions; D013696:Temperature
D000863:Antacids; D002254:Carbonates; D013535:Suspensions; C010467:hydrotalcite; D000536:Aluminum Hydroxide; D008274:Magnesium; D008276:Magnesium Hydroxide
Badanie oddziaływań zachodzacych podczas przechowywania mieszanin z grupy antacida. II. Wpływ temperatury na powstawanie hydrotalcytu w zawiesinach zobojetniajacych.