title: [Nickel-induced allergic contact dermatitis: reactivation by oral administration of hapten].
abstract: Recent reports suggest the high frequency of nickel induced allergic contact dermatitis and the absence in some patients of a clinical improvement following topical avoidance of sensitising allergen. In this study we evaluated the role of food ingested nickel in the maintenance and exacerbations of the disease. A high frequency of cutaneous exacerbations was obtained after oral challenge with a low nickel containing diet. These results suggest a pathogenetic role of nickel present in foods and indicate that an appropriate diet may be useful in the prophylaxis and in the therapy of nickel dermatitis in sensitized patients.
authors.forename: G
authors.initials: G
authors.lastname: Bezze
authors.forename: E
authors.initials: E
authors.lastname: Cassin
authors.forename: F
authors.initials: F
authors.lastname: Borghesan
authors.forename: U
authors.initials: U
authors.lastname: Fagiolo
mesh_terms: D003877:Dermatitis, Contact / Q000209:etiology* / Q000517:prevention & control; D004032:Diet; D005260:Female; D005512:Food Hypersensitivity / Q000209:etiology*; D006801:Humans; D008297:Male; D009532:Nickel / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D009532:Nickel
vernacular_title: Dermatite allergica da contatto al nichel: riacutizzazione mediante somministrazione dell'aptene per via orale.