Reptilian dorsal column nucleus lacks GAD immunoreactive neurons.
Brains of reptiles, Caiman crocodilus, were processed by standard immunocytochemical methodology using a polyclonal antibody to glutamic acid decarboxylase (GAD) as well as several monoclonal antibodies to GAD. No neurons immunoreactive for GAD, GAD(+), were observed in the dorsal column nucleus, although GAD(+) puncta were seen. These findings suggest that in Caiman, the dorsal column nucleus, like the dorsal thalamus, lacks local circuit neurons.
Pritz
M B
MB
Division of Neurological Surgery, California College of Medicine, University of California Irvine Medical Center, Orange 92668.
Stritzel
M E
ME
D000489:Alligators and Crocodiles / Q000378:metabolism*; D000818:Animals; D000911:Antibodies, Monoclonal; D005968:Glutamate Decarboxylase / Q000378:metabolism*; D012104:Reptiles / Q000378:metabolism*; D013116:Spinal Cord / Q000166:cytology / Q000378:metabolism*
D000911:Antibodies, Monoclonal; D005968:Glutamate Decarboxylase