[The morphology of the adrenals and kidney incretory structures in arterial hypertension].
Glomerular and fascicular zones of the adrenal gland and the incretory renal structures of patients who had died from benign (20) and malignant (10) forms of essential hypertension, chronic glomerulonephritis (10) and of rats with a genetic hypertension (10) were examined by morphometric methods. Hypertrophy of glomerular and fascicular zones is observed in both forms of the hypertension disease, spontaneous hypertension and chronic glomerulonephritis. Correlation analysis revealed moderate and strong links between the volumes of nuclei and nucleoli; within each zone and between the zones. This may indicate an increased functional activity of the two zones and their close interaction. Factorial analysis revealed a sign indicator--nucleus volume of the glomerular zone cells. Numerous moderate and strong correlations between the incretory renal structures and the adrenal cortex in the malignant form of the hypertension disease may indicate not only the involvement of the renin-angiotensin-aldosteron- and prostaglandin-synthesizing systems in the pathogenesis of this disease but their interaction as well.
Tsibel'
B N
BN
Grishina
L P
LP
Golubev
S S
SS
D000311:Adrenal Glands / Q000473:pathology*; D000328:Adult; D000368:Aged; D000818:Animals; D002908:Chronic Disease; D005921:Glomerulonephritis / Q000473:pathology; D006801:Humans; D006973:Hypertension / Q000473:pathology*; D006974:Hypertension, Malignant / Q000473:pathology; D006984:Hypertrophy / Q000473:pathology; D007668:Kidney / Q000378:metabolism / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY
Morfologiia nadpochechnikov i inkretornykh struktur pochek pri arterial'noĭ gipertenzii.