title: Time-based changes in fibroblast three-dimensional locomotory characteristics and phenotypes.
abstract: Three-dimensional locomotory trajectories have been determined for an embryonic fibroblast population and also for these cells after a 20-day period in tissue culture (C-20 cells). Differences in locomotory characteristics between these two cell populations are reported. Applying factor analysis to the distribution of angle changes between vectors in a cell's trajectory reveals the possibility that different locomotory phenotypes exist. Of the three phenotypes detected in the embryonic population only one continues in the C-20 population while a new phenotype appears in the latter. These results document changes in locomotory characteristics and phenotypes in an embryonic population with time.
authors.affiliation: Department of Oral Biology, Faculty of Dentistry, McGill University, Montreal, Canada.
authors.forename: P B
authors.initials: PB
authors.lastname: Noble
authors.forename: E D
authors.initials: ED
authors.lastname: Shields
mesh_terms: D000818:Animals; D002465:Cell Movement / Q000502:physiology; D002478:Cells, Cultured; D005347:Fibroblasts / Q000166:cytology* / Q000473:pathology; D006321:Heart / Q000196:embryology; D009206:Myocardium / Q000166:cytology; D010641:Phenotype; D011784:Quail; D013997:Time Factors