[Protein synthesis in the organs of the long-tailed suslik (Citellus undulatus) in various functional states].
Protein synthesis has been observed in brain and liver of susliks during hibernation using specific radioactivity assay and cycloheximide inhibitor analysis. The data on cycloheximide sensitivity and radioactivity of total protein fractions after differential centrifugation suggest that protein synthesis during hibernation is mostly carried out on microsomes. Experiments on protein synthesis in cell-free extracts from liver of suslik at various functional states indicated that the pool of polyribosomes during hibernation is similar to that during wakening period and waking state. This may ensure high intensity of protein biosynthesis at increase in body temperature during wakening.
Zagnoĭko
V I
VI
Gulevskiĭ
A K
AK
Mishneva
L G
LG
D000596:Amino Acids / Q000008:administration & dosage / Q000493:pharmacokinetics; D000818:Animals; D002250:Carbon Radioisotopes; D003513:Cycloheximide / Q000494:pharmacology; D006605:Hibernation / Q000187:drug effects / Q000502:physiology; D014176:Protein Biosynthesis; D011506:Proteins / Q000032:analysis / Q000187:drug effects; D012589:Sciuridae / Q000502:physiology*; D012621:Seasons; D014018:Tissue Distribution / Q000187:drug effects
D000596:Amino Acids; D002250:Carbon Radioisotopes; D011506:Proteins; D003513:Cycloheximide
Sintez belka v organakh dlinnokhvostykh suslikov (Citellus undulatus) pri razlichnykh funktsional'nykh sostoianiiakh.