title: Disseminated Geotrichum capitatum infection in a patient with acute myeloid leukemia.
abstract: A case of invasive Geotrichum capitatum infection is reported; a young patient had an acute leukemia for which he received a chemotherapy, and presented sepsis with blood cultures for Geotrichum capitatum, namely Dipodascus spicifer; this pathogen only described in cactus rot, is responsible for the first case of a human disseminated infection reported in literature. Then he developed a splenic and epididymic infection, with positive cultures for Geotrichum capitatum after splenectomy and castration. Treatment with amphotericin B and itraconazole was started with low minimal inhibitory concentration (0.1 microgram/ml). The patient died of massive hemoptisis. Autopsy findings demonstrated a lung, brain and kidneys seeding.
authors.forename: P
authors.initials: P
authors.lastname: Mahul
authors.forename: M A
authors.initials: MA
authors.lastname: Piens
authors.forename: D
authors.initials: D
authors.lastname: Guyotat
authors.forename: J
authors.initials: J
authors.lastname: Godard
authors.forename: E
authors.initials: E
authors.lastname: Archimbaud
authors.forename: B
authors.initials: B
authors.lastname: Bui-Xuan
authors.forename: J
authors.initials: J
authors.lastname: Motin
mesh_terms: D000328:Adult; D005847:Geotrichosis / Q000209:etiology*; D006801:Humans; D007108:Immune Tolerance; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008297:Male; D009181:Mycoses / Q000209:etiology*