Acute renal failure and nephrotic syndrome after maneb exposure. A new case with light and electron microscopic study.
A new case of nephrotoxic effect of Maneb is related. The patient used this product as fungicide and developed a progressive illness with acute renal failure. The study by light and electron microscopy revealed severe tubular lesions that disappeared some months later with tubular cell regeneration. However, in spite of the renal function returning to normal, a steroid-dependent nephrotic syndrome persisted with glomerular minimal change like lesions.
de Carvalho
E
E
Faria
V
V
Loureiro
A
A
Miranda
V
V
D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000473:pathology; D001706:Biopsy; D006801:Humans; D007687:Kidney Tubules, Proximal / Q000187:drug effects / Q000648:ultrastructure; D008297:Male; D008344:Maneb / Q000009:adverse effects*; D008854:Microscopy, Electron; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000139:chemically induced* / Q000473:pathology; D013859:Thiocarbamates / Q000009:adverse effects*
D013859:Thiocarbamates; D008344:Maneb