title: [The effect of experimental infarct and emotional-pain stress on the endothelium-dependent reactions of the isolated rat aorta].
abstract: Emotional-nociceptive stress, stress induced with a myocardial infarction, and stress following sham operation increased the effect of endothelium on the force and velocity of the smooth muscle contraction. Within 2 hrs after stress and 3 hrs after the coronary artery ligation, a considerable drop occurred in the rat arterial pressure followed by a facilitation of the aorta endothelium-dependent relaxation. Both these parameters were restored to the control level within 24 hrs. The facilitation of the endothelium-dependent relaxation of vascular wall seems to play a role in the drop of the vessels tone, in decrease of arterial pressure and, finally, in development of the cardiogenic shock in myocardial infarction in humans.
authors.forename: E B
authors.initials: EB
authors.lastname: Manukhina
authors.forename: A V
authors.initials: AV
authors.lastname: Lapshin
authors.forename: E E
authors.initials: EE
authors.lastname: Ustinova
authors.forename: F Z
authors.initials: FZ
authors.lastname: Meerson
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D001011:Aorta / Q000187:drug effects / Q000503:physiopathology; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology; D004730:Endothelium, Vascular / Q000187:drug effects / Q000503:physiopathology*; D066298:In Vitro Techniques; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects / Q000502:physiology; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000502:physiology; D009203:Myocardial Infarction / Q000503:physiopathology*; D009638:Norepinephrine / Q000494:pharmacology; D010146:Pain / Q000503:physiopathology*; D051381:Rats; D011919:Rats, Inbred Strains; D013315:Stress, Psychological / Q000503:physiopathology*
chemical_list: D000109:Acetylcholine; D009638:Norepinephrine
vernacular_title: Vliianie éksperimental'nogo infarkta i émotsional'no-bolevogo stressa na éndoteliĭzavisimye reaktsii izolirovannoĭ aorty krysy.