Deuterium-labeled 3-nitrobenzyl alcohol as a matrix for fast atom bombardment mass spectrometry.
The utility of deuterium-labeled 3-nitrobenzyl alcohol (DNBA) as a fast atom bombardment (FAB) matrix for establishing the number of exchangeable hydrogens present in a molecule is illustrated by the analysis of five selected antitumor agents. A method for the simple preparation of this labeled matrix is described. The use of DNBA may be of value for samples which provide no FAB spectra when deuterium-labeled glycerol is used as a matrix.
Reddy
A M
AM
Department of Pharamaceutical Sciences, College of Pharmacy, University of Arizona, Tucson 85721.
Mykytyn
V V
VV
Schram
K H
KH
D001592:Benzyl Alcohols; D001593:Benzyl Compounds; D003903:Deuterium; D007202:Indicators and Reagents; D013058:Mass Spectrometry
D001592:Benzyl Alcohols; D001593:Benzyl Compounds; D007202:Indicators and Reagents; D003903:Deuterium; C046886:3-nitrobenzyl alcohol