[Protection systems of erythrocytes during intraoperative autotransfusion. Experience with the use of S-adenosyl-L-methionine].
An experiment lasting 2 years in more than 200 patients in single blind conditions (S-Adenosyl-L-Methionine vs placebo) aimed to improve protection of red cells during intraoperative autotransfusion. The two groups are analysed and, on the basis of objective hematochemical data it is concluded that in patients treated with the pharmacological support erythrocyte membrane stability is good.
Giorgetti
P L
PL
Bortolani
E M
EM
Mattioli
A
A
Morbidelli
A
A
Marenghi
M C
MC
Giordanengo
F
F
D001804:Blood Transfusion, Autologous; D017707:Erythrocyte Transfusion; D004912:Erythrocytes / Q000187:drug effects; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D007432:Intraoperative Period; D011292:Premedication; D012436:S-Adenosylmethionine / Q000627:therapeutic use*
D006454:Hemoglobins; D012436:S-Adenosylmethionine
Sistemi di protezione delle emazie in corso di autotrasfusione intraoperatoria. Esperienza sull'uso della S-adenosil-L-metionina (SAMe).