Neutropenia in an infant: possible autoimmune etiology.
The present study was undertaken to determine if the serum of a child with severe neutropenia contained antibodies against parental neutrophils. The presence of IgG antibodies to granulocytes from both parents was demonstrated using the indirect immunofluorescence technique. These data suggest an autoimmune etiology for the neutropenia of this patient.
De-Araujo
A C
AC
Seção de Imunologia, Instituto Adolfo Lutz, São Paulo, Brasil.
De-Los-Santos-Fortuna
E
E
Ionemoto
H F
HF
Jacob
C M
CM
D000380:Agranulocytosis / Q000209:etiology*; D001323:Autoantibodies / Q000276:immunology*; D001327:Autoimmune Diseases / Q000209:etiology*; D001772:Blood Cell Count; D001803:Blood Transfusion; D017707:Erythrocyte Transfusion; D006801:Humans; D007223:Infant; D008297:Male; D009503:Neutropenia / Q000209:etiology* / Q000628:therapy; D009504:Neutrophils / Q000032:analysis / Q000276:immunology*
D001323:Autoantibodies