[Ethambutol and the optic nerve].
Author describe two clinical observations of optic neuropathy due to the systemic absorption of antibiotics used against tuberculosis. Two items are pointed out: swelling of the optic disc and functional improvement of electro-physiologic and colorimetric tests 6 months after the end of the treatment. He think that optic disc swelling is the clinical manifestation of an anatomical and volumetrical increase of the neuronal axon due to blockade of the axoplasmic transport without demyelinating lesions. This could explain the functional improvement.
Hamard
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D004977:Ethambutol / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000139:chemically induced*; D010211:Papilledema / Q000139:chemically induced; D013997:Time Factors
D004977:Ethambutol
Ethambutol et nerf optique.