Bioactive polymers. LX. Kinetics of delayed release neomycin-xanthan complex.
The kinetics of delayed release neomycin-xanthan complex, and its antimicrobial activity, were studied. Delayed release neomycin (53.13% free neomycin) had zero-order release kinetics, when artificial tear solution was used as eluent. Microbiological tests revealed an activity of 380 units/mg, 10% higher than neomycin in its free form.
Beldie
C
C
Polytechnic Institute of Jassy, Romania.
Dumitriu
S
S
Aelenei
N
N
Popa
M
M
Popa
M I
MI
Dumitriu
D
D
D003692:Delayed-Action Preparations; D066298:In Vitro Techniques; D009355:Neomycin / Q000493:pharmacokinetics*; D011135:Polysaccharides, Bacterial / Q000493:pharmacokinetics*; D019736:Prostheses and Implants
D003692:Delayed-Action Preparations; D011135:Polysaccharides, Bacterial; D009355:Neomycin; C002563:xanthan gum