The effect of vitamin E therapy on plasma and erythrocyte lipid peroxidation in chronic hemodialysis patients.
The effect of vitamin E therapy on plasma and erythrocyte (RBC) lipid peroxidation was investigated in patients undergoing chronic hemodialysis. Before vitamin E therapy, both plasma and RBC lipid peroxidation values of chronic hemodialysis patients were significantly higher than those of healthy controls. Treatment with vitamin E (300 mg/day) for 1 month resulted in a significant decrease of lipid peroxidation. Vitamin E therapy may be a promising approach to prevent peroxidation of membrane lipids in chronic renal failure.
Yalçin
A S
AS
Department of Biochemistry, Faculty of Medicine, Marmara University, Istanbul, Turkey.
Yurtkuran
M
M
Dilek
K
K
Kilinç
A
A
Taga
Y
Y
Emerk
K
K
D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000628:therapy*; D015227:Lipid Peroxidation; D008315:Malondialdehyde / Q000097:blood; D008563:Membrane Lipids / Q000097:blood; D006435:Renal Dialysis; D014810:Vitamin E / Q000097:blood / Q000627:therapeutic use*
D008563:Membrane Lipids; D014810:Vitamin E; D008315:Malondialdehyde