Monitoring therapeutic response of human superficial tumors using phase-encoded spectroscopy.
A one-dimensional phase-encoded spectroscopy sequence was implemented on a GE 1.5-T Signa imager and the feasibility of its application to monitor the 31P metabolites of superficial tumors was demonstrated. Serial 31P spectra of 1-cm slices with adequate signal-to-noise ratio and insignificant T2 weighting can be obtained in 28 min. The degree of "bleeding" effect was reduced with increased phase-encoding steps.
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MR Research, Division of Radiology, Cleveland Clinic Foundation, Ohio 44106.
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D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D008961:Models, Structural; D009369:Neoplasms / Q000378:metabolism* / Q000628:therapy; D010758:Phosphorus
D010758:Phosphorus