[Drug-induced cardiovascular complications].
Many drugs, including those prescribed in cardiology, can induce adverse cardiovascular side effects. Most of the anti-arrhythmia drugs have a negative inotropic action and proarrhythmic effects. Estroprogestative contraceptive drugs favor thromboembolitic events and increase the incidence of hypertension. Due to the risk of coronary insufficiency, substitutive hormonotherapy in hypothyroidism must be introduced gradually. Tricyclic anti-depressive drugs and neuroleptics can induce orthostatic hypotension. However, all these adverse effects can usually be avoided if every drug-specific contra-indication is respected, if doses are individually adjusted to the patient's age and physical condition and if the patient is closely monitored.
Le Feuvre
C
C
Clinique Cardiologique, Hôpital Necker, Paris.
Baubion
N
N
Berdah
J
J
Heulin
A
A
Vacheron
A
A
D000889:Anti-Arrhythmia Agents / Q000009:adverse effects; D002316:Cardiotonic Agents / Q000009:adverse effects; D002318:Cardiovascular Diseases / Q000139:chemically induced*; D064420:Drug-Related Side Effects and Adverse Reactions; D006728:Hormones / Q000009:adverse effects; D006801:Humans; D011619:Psychotropic Drugs / Q000009:adverse effects
D000889:Anti-Arrhythmia Agents; D002316:Cardiotonic Agents; D006728:Hormones; D011619:Psychotropic Drugs
Accidents cardiovasculaires d'origine médicamenteuse.