title: [Histochemical evaluation of the distribution of chloride ion around retinal pigment epithelium in various animal species].
abstract: In order to clarity the distribution of chloride ion around pigment epithelium, chloride ion was deposited as silver chloride (AgCl) in the tissue and observed electron microscopically. Eyes of albino rabbits, bullfrogs, mature chick embryos immediately before hatching and a human patient were used. In the albino rabbit eyes, the chick embryo eyes and the human eye, the concentration of chloride ion in the cytoplasm of retinal pigment epithelium (RPE) was high, and in the bullfrog eyes, the concentration was low. The difference among animal species is probably due to the difference of the ion transport mechanism by retinal pigment epithelium among species. In all the animals examined, chloride ion was concentrated in the intercellular space, which may be related to the isotonic absorption of water by RPE according to the standing-gradient osmotic flow theory of Diamond and Bossert.
authors.forename: H
authors.initials: H
authors.lastname: Yamashita
authors.forename: T
authors.initials: T
authors.lastname: Yamamoto
mesh_terms: D000818:Animals; D002642:Chick Embryo; D002713:Chlorine / Q000378:metabolism*; D006651:Histocytochemistry; D006801:Humans; D007477:Ions; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000378:metabolism*; D011817:Rabbits; D011892:Rana catesbeiana; D013045:Species Specificity
chemical_list: D007477:Ions; D002713:Chlorine