Computerized estimation of spontaneous and evoked acetylcholine release at the neuromuscular junction.
A new and automated on-line analysis of the parameters related to the neuromuscular activity is shown. The procedure used to obtain in real time the statistical evaluation of the recorded electrical signals is presented and discussed. The hardware is composed of a PDP-11/73 microcomputer equipped with an analog input/output board. The software is written principally in FORTRAN 77 and also uses MACRO/ASSEMBLY language.
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Institute of Experimental and Clinical Medicine, University of Ancona, Italy.
Di Sarra
B
B
Concettoni
C
C
Giusti
P
P
D000109:Acetylcholine / Q000493:pharmacokinetics*; D000818:Animals; D003964:Diaphragm / Q000294:innervation; D001330:Electronic Data Processing; D005071:Evoked Potentials; D051379:Mice; D009469:Neuromuscular Junction / Q000378:metabolism*; D010791:Phrenic Nerve / Q000187:drug effects; D012984:Software
D000109:Acetylcholine