Genetic polymorphism of the B subunit of coagulation factor XIII in Libyans: occurrence of a fourth common allele, FXIIIB*6.
FXIIIB phenotypes were determined in neuraminidase-pretreated serum samples by using isoelectric focusing in ultrathin-layer polyacrylamide gels containing 1 M urea and subsequent immunoblotting. In a Libyan population sample from Tripoli, (n = 108) nine different phenotypes as products of four common alleles were recognized, with frequencies as follows: FXIIIB*1 = 0.6574, FXIIIB*2 = 0.2454, FXIIIB*3 = 0.0741 and FXIIIB*6 = 0.0231. It is suggested that FXIIIB*6 is the fourth common allele of the FXIIIB system in this population.
Sebetan
I M
IM
Department of Laboratory Medicine and Pathology, Hamad General Hospital, Doha, Qatar.
Azadeh
B
B
D000483:Alleles; D005176:Factor XIII / Q000235:genetics*; D005819:Genetic Markers; D005828:Genetics, Population; D006801:Humans; D008002:Libya; D010641:Phenotype; D011110:Polymorphism, Genetic
D005819:Genetic Markers; D005176:Factor XIII; C054380:factor XIIIb