[Synthesis of racemates and enantiomers of 3-alkylthalidomide analogs and determination of their absolute configuration].
The syntheses of the racemates and the enantiomers of the title compounds 7a-7c and of racem. 1,3-dimethyl-thalidomide (8) are reported. The absolute configuration of the optically active products is determined. The hypnotic activities of the analogs of thalidomide 7a - 7c and of the intermediates 6a - 6c are to be tested in animals.
Knabe
J
J
Omlor
G
G
D055598:Chemical Phenomena; D002621:Chemistry; D008968:Molecular Conformation; D013237:Stereoisomerism; D013792:Thalidomide / Q000031:analogs & derivatives* / Q000138:chemical synthesis
D013792:Thalidomide
Synthese der Racemate und der Enantiomere von 3-Alkylthalidomidanaloga und Bestimmung ihrer absoluten Konfiguration.