[Solar keratosis. Morphometric observations on atypia and polarity of keratinocytes of the basal stratum].
Nuclear morphometric parameters and polarity of basal keratinocytes have been evaluated by computerized image analysis in solar keratoses, comparing the results with normal sun-exposed skin and squamous cell carcinoma 1st Broders degree. The cellular index demonstrated higher levels in all keratoses. The morphometric nuclear parameters revealed major values in atrophic, bowenoid, acantholytic, hypertrophic and pigmented solar keratoses, respectively. The loss of polarity demonstrated higher levels in bowenoid, atrophic, hypertrophic, pigmented and acantholytic histotypes, respectively. Solar keratoses could be classified as in situ carcinomas rather than precancerous lesions.
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D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D006801:Humans; D015603:Keratinocytes / Q000473:pathology*; D007642:Keratosis / Q000209:etiology / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*; D013472:Sunlight / Q000009:adverse effects*
Cheratosi solari. Osservazioni morfometriche su atipie e polarità dei cheratinociti dello strato basale.