[Preparation and characteristics of monoclonal antibodies to DNA-dependent RNA-polymerase of bacteriophage T7].
The monoclonal antibodies to DNA-dependent RNA-polymerase of bacteriophage T7 have been obtained. Twenty of the obtained 500 clones have inhibited the enzyme activity. Three specificity groups were identified for seven of the clones supporting their affinity for different antigenic determinants.
Degtiarev
I L
IL
Shumakova
E I
EI
Vorob'ev
S M
SM
Kostiuk
D A
DA
Kochetkov
S N
SN
D000818:Animals; D000911:Antibodies, Monoclonal / Q000302:isolation & purification*; D002999:Clone Cells; D012321:DNA-Directed RNA Polymerases / Q000276:immunology* / Q000378:metabolism; D004591:Electrophoresis, Polyacrylamide Gel; D051379:Mice; D008807:Mice, Inbred BALB C; D013604:T-Phages / Q000201:enzymology*
D000911:Antibodies, Monoclonal; D012321:DNA-Directed RNA Polymerases
Poluchenie i kharakteristiki monoklonal'nykh antitel k DNK- zavisimoĭ RNK-polimeraze bakteriofaga T7.