title: [Immunologic status of patients with acute altitude sickness].
abstract: T- and B-cells were examined in 56 patients with acute mountain sickness exposed to 3600 m above sea level. They showed T- and B-lymphopenia, decreased PHA- and Con A-induced blast formation from T-cells, reduced content of T mu cells and increased content of T gamma and 0 cells. These changes persisted for as long as 5 months. It was demonstrated that individuals susceptible to acute mountain sickness had a lower level of E-RFC and T mu cells and a higher level of 0 cells. These characteristics seen in the baseline produced a negative effect on the adaptation process.
authors.forename: M M
authors.initials: MM
authors.lastname: Mirrakhimov
authors.forename: M I
authors.initials: MI
authors.lastname: Kitaev
authors.forename: A G
authors.initials: AG
authors.lastname: Tokhtabaev
mesh_terms: D000208:Acute Disease; D000222:Adaptation, Physiological / Q000276:immunology; D000293:Adolescent; D000328:Adult; D000531:Altitude; D000532:Altitude Sickness / Q000276:immunology*; D001402:B-Lymphocytes / Q000276:immunology*; D006801:Humans; D000860:Hypoxia / Q000276:immunology*; D007958:Leukocyte Count; D008213:Lymphocyte Activation / Q000276:immunology; D008297:Male; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*
vernacular_title: Immunnyĭ status bo'lnykh ostroĭ gornoĭ bolez'niu.