title: Structure and synthesis of FK409, a novel vasodilator isolated from Streptomyces as a semi-artificial fermentation product.
abstract: The structures of FK409 (1), a semi-artificial fermentation product and its precursor (2) have been established on the basis of chemical and spectroscopic evidence and confirmed by conversion of 2 to 1 via a synchronous nitrosation-nitration reaction.
authors.forename: M
authors.initials: M
authors.lastname: Hino
authors.forename: S
authors.initials: S
authors.lastname: Takase
authors.forename: Y
authors.initials: Y
authors.lastname: Itoh
authors.forename: I
authors.initials: I
authors.lastname: Uchida
authors.forename: M
authors.initials: M
authors.lastname: Okamoto
authors.forename: M
authors.initials: M
authors.lastname: Hashimoto
authors.forename: M
authors.initials: M
authors.lastname: Kohsaka
mesh_terms: D005285:Fermentation; D009574:Nitro Compounds / Q000032:analysis* / Q000138:chemical synthesis; D013302:Streptomyces / Q000378:metabolism*; D014665:Vasodilator Agents / Q000032:analysis* / Q000138:chemical synthesis
chemical_list: D009574:Nitro Compounds; D014665:Vasodilator Agents; C061872:FK 409