Reactive oxygen species production in circulating polymorphonuclear leukocytes in psoriasis.
Metabolic burst of polymorphonuclear leukocytes was evaluated by means of a luminol-enhanced chemiluminescence assay. Patients affected with active psoriasis showed a higher response than patients with chronic disease and controls when the neutrophils were stimulated with opsonized zymosan or phorbol myristate acetate.
De Simone
C
C
Department of Dermatology, Catholic University, Rome, Italy.
De Sole
P
P
Di Mario
G
G
Venier
A
A
Cerimele
D
D
Serri
F
F
D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008163:Luminescent Measurements; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000378:metabolism* / Q000502:physiology; D011565:Psoriasis / Q000097:blood / Q000378:metabolism*; D013755:Tetradecanoylphorbol Acetate / Q000378:metabolism; D015054:Zymosan / Q000378:metabolism
D015054:Zymosan; D013755:Tetradecanoylphorbol Acetate