title: The development of activity of lactate dehydrogenase (EC 1.1.1.27) in the areas of nigro-striatal pathway during the ontogenesis of pig.
abstract: The development of activity of lactate dehydrogenase was investigated by histochemical methods under the light and electron microscopes and also by biochemical methods. The studies were carried out in the areas of the nigro-striatal pathway of 7 foetal groups, two days-old piglets, three weeks old piglets and adult pigs. It was demonstrated that the activity of LDH appears early in the prenatal ontogenesis. High activity of the enzyme appears in the studied areas of the brain already in foetuses about 60 days old (100 mm) afterwards it rises and the highest activity is observed in about 86 days old foetuses. It then decreases just before birth. After birth in two days and three weeks old piglets the LDH activity decreases further. In adults a high activity of the examined enzyme was confirmed.
authors.affiliation: Department of Histology and Embriology, Agricultural Academy, Lublin, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Jaworska-Adamu
mesh_terms: D000818:Animals; D003342:Corpus Striatum / Q000196:embryology / Q000201:enzymology* / Q000254:growth & development; D005314:Embryonic and Fetal Development; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D013378:Substantia Nigra / Q000196:embryology / Q000201:enzymology* / Q000254:growth & development; D013552:Swine / Q000254:growth & development*
chemical_list: D007770:L-Lactate Dehydrogenase