[The stereologic-quantitative analysis of gastric antrum G cells in patients with splenic diseases].
In this paper, 89 Spleen deficiency (SD) patients' gastric mucosa specimens obtained during fibrogastroscopy mucosal biopsy were observed with immunocytochemical-stereologic-quantitative analysis method. The number of G cells counted and the content of basic gastrin in serum measured. This study found that the difference of the number of G cells and the content of gastrin in serum possessed statistical significance between two types of SD. The results suggested the hyperplasia and hypersecretion of G cells in gastric antrum might be an important pathological mechanism for different types of SD.
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D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology*; D005755:Gastrins / Q000032:analysis; D005756:Gastritis / Q000473:pathology; D005773:Gastroscopy; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D010437:Peptic Ulcer / Q000473:pathology; D011706:Pyloric Antrum / Q000473:pathology*; D013158:Splenic Diseases / Q000473:pathology*
D005755:Gastrins