Non-apatitic environments in bone mineral: FT-IR detection, biological properties and changes in several disease states.
Resolution enhanced FT-IR spectroscopy shows that non-apatitic environments of phosphate and carbonate ions occur in bone mineral. The spectroscopic characteristics of these environments and their chemical and biological properties are reviewed. The potential effectiveness of FT-IR for the detailed study of bone mineral changes in bone disease is shown by analysis of several samples.
Rey
C
C
Laboratory for the Study of Skeletal Disorders, Children's Hospital, Harvard Medical School, Boston, MA.
Lian
J
J
Grynpas
M
M
Shapiro
F
F
Zylberberg
L
L
Glimcher
M J
MJ
D000818:Animals; D001031:Apatites; D015519:Bone Density; D001847:Bone Diseases / Q000378:metabolism*; D002254:Carbonates / Q000032:analysis*; D005399:Fishes; D005458:Fluoride Poisoning / Q000378:metabolism; D006801:Humans; D010710:Phosphates / Q000032:analysis* / Q000097:blood; D013055:Spectrophotometry, Infrared / Q000379:methods; D014808:Vitamin D Deficiency / Q000378:metabolism
D001031:Apatites; D002254:Carbonates; D010710:Phosphates