title: Effect of oral bacterial lysates on serum immunoglobulins.
abstract: The level of serum immunoglobulins IgG, IgA, IgM and IgE has been studied before and after oral immunotherapy with a bacterial lysate in 88 patients with bronchial asthma, repeated respiratory infection and 12 cases of IgA deficiency. A significant increase in IgA has been observed in 9 patients presenting initially a decreased IgA serum level. In 3 patients without response to the standard treatment an increase in IgA was achieved increasing the dosage of oral bacterial lysate. Oral bacterial lysates could be an useful immunomodulating agent in repeated respiratory infections associated or not with IgA deficiency.
authors.affiliation: Instituto de Imunologia, CHIUL, Fac Medicina, Lisboa, Portugal.
authors.forename: A G
authors.initials: AG
authors.lastname: Palma-Carlos
authors.forename: M L
authors.initials: ML
authors.lastname: Palma-Carlos
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology* / Q000627:therapeutic use; D000328:Adult; D000942:Antigens, Bacterial / Q000494:pharmacology* / Q000627:therapeutic use; D001249:Asthma / Q000276:immunology* / Q000628:therapy; D001419:Bacteria; D002457:Cell Extracts; D002648:Child; D004406:Dysgammaglobulinemia / Q000276:immunology*; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology* / Q000628:therapy; D017098:IgA Deficiency; D017099:IgG Deficiency; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D012008:Recurrence; D012141:Respiratory Tract Infections / Q000276:immunology* / Q000628:therapy; D000095983:Bacterial Lysates
chemical_list: D000276:Adjuvants, Immunologic; D000942:Antigens, Bacterial; D002457:Cell Extracts; D007136:Immunoglobulins; C030259:Broncho-Vaxom; D000095983:Bacterial Lysates