[Electron microscopic study of glycoconjugate in nasal mucosa of nasal allergy by lectin histochemistry].
Glycoconjugates in glandular and goblet cells of nasal mucosa were compared between normal and nasal allergy by using various horseradish peroxidase (HRP)-conjugated lectins; WGA, PNA, UEA-I and RCA-I. Specific sugar residues of glycoconjugates could be identified under electron microscope. Golgi's complex of the serous secretory cells in nasal allergic mucosa had positive staining in UEA-I. Goblet cells of nasal allergic mucosa were stained strongly in PNA, compared to normal mucosa, however, they were stained weakly in WGA. In conclusion, glycoconjugates in glandular and goblet cells seem to be changed in nasal allergy.
Jin
C S
CS
Ukai
K
K
Sakakura
Y
Y
Yamada
H
H
Masuda
S
S
D006001:Glycoconjugates / Q000032:analysis*; D006651:Histocytochemistry; D006801:Humans; D037102:Lectins; D008854:Microscopy, Electron; D009297:Nasal Mucosa / Q000032:analysis* / Q000648:ultrastructure; D012221:Rhinitis, Allergic, Perennial / Q000378:metabolism* / Q000473:pathology; D006255:Rhinitis, Allergic, Seasonal / Q000378:metabolism* / Q000473:pathology
D006001:Glycoconjugates; D037102:Lectins