Amitriptyline overdose complicated by intestinal pseudo-obstruction and caecal perforation.
I report a case of intestinal pseudo-obstruction, spontaneous caecal perforation and faecal peritonitis caused by an overdose of amitriptyline. This rare but serious complication should be borne in mind in patients who remain constipated while convalescing after self-poisoning with tricyclic antidepressants.
McMahon
A J
AJ
Department of General Surgery, Southern General Hospital, Glasgow, UK.
D000328:Adult; D000639:Amitriptyline / Q000506:poisoning*; D002429:Cecal Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000601:surgery; D062787:Drug Overdose / Q000150:complications*; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000601:surgery; D008297:Male; D011859:Radiography; D012422:Rupture, Spontaneous
D000639:Amitriptyline