Prevention of coronary heart disease: some results from the Oslo secondary and primary intervention studies.
The increase in cardiac disease [fatal and nonfatal myocardial infarction (MI), and sudden death] in the post-war years in Norway, after the much lower incidence during the war, that coincided with high and low fat intakes, respectively, led to a trial in Oslo to determine whether lowering dietary fat intake would favorably influence occurrence of coronary heart disease (CHD). Dietary modification, which lowered serum cholesterol of men who had suffered a first-time MI, showed decreased reinfarction incidence and cardiac deaths as compared with a comparable group of controls. Another study of normotensive high-risk men (on the basis of serum cholesterol and smoking habits) showed that dietetic measures can be useful in preventing CHD.
Leren
P
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University of Oslo, Medical School, Medical Department, Ullevaal Hospital, Norway.
D000328:Adult; D003327:Coronary Disease / Q000178:diet therapy / Q000517:prevention & control*; D004032:Diet; D004041:Dietary Fats / Q000009:adverse effects*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009664:Norway; D011322:Primary Prevention
D004041:Dietary Fats