Immunological screening of welders.
74 healthy welders were subjected to immunological screening. Serum immunoglobulins (IgG, IgA, IgM) were measured as well as total and active E-RFC and cellular immunity was evaluated using the intradermal testing of PPD, candidin D-7, trichophytin D-5 and tetanus anatoxin. The obtained results suggest suppression of the T and B lymphocyte immune systems as expressed by decreased levels of serum IgG and total E-RFC. Cell-mediated immune deficiency was found in 21.6% welders. Suppression of the immune system may be accounted for by a complex effect of occupational factors, such as manganese compounds, vibration and noise.
Boshnakova
E
E
Department of Biology, Higher Medical Institute, Varna, Bulgaria.
Divanyan
H
H
Zlatarov
I
I
Marovsky
S
S
Kisyova
K
K
Zanev
D
D
Karev
G
G
Marinova
T
T
D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology; D002031:Bulgaria; D004781:Environmental Exposure; D006801:Humans; D007108:Immune Tolerance; D007074:Immunoglobulin G / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D008345:Manganese / Q000009:adverse effects; D008875:Middle Aged; D015166:Monitoring, Immunologic; D013601:T-Lymphocytes / Q000276:immunology; D014896:Welding
D007074:Immunoglobulin G; D007136:Immunoglobulins; D008345:Manganese