Comparative study of miconazole and clotrimazole in superficial mycosis.
Two hundred cases of superficial mycosis (100 dermatophytosis, 40 candidiasis and 60 pityriasis versicolor) were studied for the comparative effect of miconazole and clotrimazole. The patients were evaluated both clinically and mycologically every 2 weeks for a period of 12 weeks. In dermatophytosis, miconazole showed accelerated response (75% cleared in 6 weeks) than clotrimazole (56%). In candidiasis, both were found to be effective (80-85%) cure though clotrimazole showed slightly earlier response (40% cure in 6 weeks) against miconazole (30% cure). In pityriasis versicolor both were, effective (miconazole 99.6% and clotrimazole 86.7%).
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D002179:Candidiasis, Cutaneous / Q000188:drug therapy*; D003022:Clotrimazole / Q000627:therapeutic use*; D003881:Dermatomycoses / Q000188:drug therapy*; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use*; D008825:Miconazole / Q000627:therapeutic use*; D009260:Nail Diseases / Q000188:drug therapy; D013997:Time Factors; D014010:Tinea Versicolor / Q000188:drug therapy*
D007093:Imidazoles; D008825:Miconazole; D003022:Clotrimazole