Evaluation of metal implants coated with several types of ceramics as biomaterials.
The in vivo biocompatibility of metals coated with several different types of ceramics [alumina (alpha-Al2O3), titanium oxide (TiO2), titanium nitride (TiN), and hydroxyapatite (HAP)] was investigated. These composites had been devised for the purpose of incorporation into the stem of a total hip prosthesis. The materials were inserted into the mid-diaphyseal region of the femurs of adult dogs, and follow-up quantitative histological comparisons were performed for a period of up to 96 weeks. HAP-coated composites showed the best biocompatibility.
Hayashi
K
K
Department of Orthopaedic Surgery, Kyushu University, Fukuoka, Japan.
Matsuguchi
N
N
Uenoyama
K
K
Kanemaru
T
T
Sugioka
Y
Y
D000537:Aluminum Oxide / Q000032:analysis / Q000494:pharmacology; D000818:Animals; D001672:Biocompatible Materials; D002516:Ceramics / Q000032:analysis / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D004285:Dogs; D006622:Hip Prosthesis; D006882:Hydroxyapatites / Q000032:analysis / Q000494:pharmacology; D008422:Materials Testing; D013193:Stainless Steel / Q000494:pharmacology; D014025:Titanium / Q000032:analysis / Q000494:pharmacology
D001672:Biocompatible Materials; D006882:Hydroxyapatites; D013193:Stainless Steel; D014025:Titanium; D000537:Aluminum Oxide