[The role of chloride ions in histamine-induced electric reactions of the glandular cells of the stomach].
The effect of Cl- ions on electrical response of gastric gland cells to histamine was investigated using intracellular glass microelectrodes. It was established that in chloride-free solution and in solution with a blocker of chloride transport the hyperprolarization evoked by histamine after 15-20 min decreased and then it was not observed. It is suggested that the chloride ions are necessary for hyperpolarization response of gastric gland cells to histamine actions.
Smirnova
Zh P
ZhP
Ome'lianiuk
V S
VS
D000818:Animals; D002712:Chlorides / Q000494:pharmacology*; D002927:Cimetidine / Q000494:pharmacology; D003470:Culture Media; D005088:Exocrine Glands / Q000166:cytology / Q000187:drug effects* / Q000502:physiology; D005753:Gastric Mucosa / Q000166:cytology / Q000187:drug effects* / Q000502:physiology; D006632:Histamine / Q000494:pharmacology*; D006633:Histamine Antagonists; D066298:In Vitro Techniques; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D051381:Rats
D002712:Chlorides; D003470:Culture Media; D006633:Histamine Antagonists; D002927:Cimetidine; D006632:Histamine
Ro'l ionov khlora v élektricheskikh reaktsiiakh zhelezistykh kletok zheludka, vyzvannykh gistaminom.