[The trace element composition of the organs and tissues of animals administered a highly dispersed powder and copper sulfate].
Changes in the content of microelements in blood, heart and liver after a single subcutaneous injection of aquatic suspension of highly dispersed powder and copper sulphate in different doses were investigated. Injection of highly dispersed powder and copper sulphate was shown increase phase fluctuations of copper, zinc and iron level in all organs under study. It was demonstrated that irrespective of the form and dose of injection copper does not break interrelation modus between zinc and copper, characteristic of the control and does not change zinc/copper ratio. Bioavailability of highly dispersed copper powder injected in organism at the dose 0.2 mg/kg was found to be somewhat higher than that of sulphate.
Bogoslovskaia
O A
OA
Glushchenko
N N
NN
Fedorov
Iu I
IuI
D000818:Animals; D003300:Copper / Q000008:administration & dosage* / Q000032:analysis / Q000378:metabolism / Q000493:pharmacokinetics; D019327:Copper Sulfate; D007279:Injections, Subcutaneous; D007501:Iron / Q000032:analysis / Q000378:metabolism; D008297:Male; D011208:Powders; D051381:Rats; D011919:Rats, Inbred Strains; D013535:Suspensions; D013997:Time Factors; D014018:Tissue Distribution; D014131:Trace Elements / Q000032:analysis / Q000378:metabolism*; D015032:Zinc / Q000032:analysis / Q000378:metabolism
D011208:Powders; D013535:Suspensions; D014131:Trace Elements; D003300:Copper; D007501:Iron; D015032:Zinc; D019327:Copper Sulfate
Mikroélementnyĭ sostav organov i tkaneĭ zhivotnykh pri vvedenii vysokodispersnogo poroshka i sul'fata medi.