Combined treatment with surgery and intraperitoneal hyperthermic perfusion (IPHP) for far-advanced gastrointestinal cancer with peritoneal seeding.
In 19 patients with advanced gastric carcinoma intraperitoneal hyperthermia combined with mitomycin C was administered. After this therapy in repeated cytological examinations of the peritoneal effusion malignant cells could be determined. From 19 patients 5 died innert the first 10 months. The other patients lived 12 months without recurrence.
Fujimoto
S
S
1st Department of Surgery, School of Medicine, Chiba University, Japan.
Shrestha
R D
RD
Kobayashi
K
K
Koike
S
S
Kokubun
M
M
Kiuchi
S
S
Takahashi
M
M
Konno
C
C
Okui
K
K
D010478:Chemotherapy, Cancer, Regional Perfusion / Q000295:instrumentation*; D003131:Combined Modality Therapy; D006801:Humans; D006979:Hyperthermia, Induced / Q000295:instrumentation*; D010534:Peritoneal Neoplasms / Q000556:secondary* / Q000628:therapy; D013274:Stomach Neoplasms / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D015996:Survival Rate; D014407:Tumor Cells, Cultured / Q000473:pathology