The effects of UK-79,300, an orally-absorbed atriopeptidase inhibitor, in a conscious dog model of cardiac insufficiency.
Alabaster
C T
CT
Discovery Biology, Pfizer Central Research, Sandwich, Kent.
Machin
I
I
Samuels
G M
GM
Sutton
M R
MR
D000818:Animals; D003509:Cyclohexanecarboxylic Acids; D004231:Diuresis / Q000187:drug effects*; D004285:Dogs; D006327:Heart Block / Q000188:drug therapy* / Q000503:physiopathology; D007189:Indans / Q000494:pharmacology*; D007192:Indenes / Q000494:pharmacology*; D009318:Natriuresis / Q000187:drug effects*; D015260:Neprilysin / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D011422:Propionates / Q000494:pharmacology*; D013237:Stereoisomerism
D003509:Cyclohexanecarboxylic Acids; D007189:Indans; D007192:Indenes; D011422:Propionates; C060942:candoxatrilat; C062766:candoxatril; D015260:Neprilysin