title: Discordant, non-syndromic, congenital diaphragmatic defects in sibs.
abstract: We report an Arab sibship of two brothers with non-syndromic, congenital diaphragmatic defects (CDD). The first had an extensive, left, Bochdalek-type hernia and the second hemidiaphragmatic agenesis; these were verified by surgical exploration and necropsy respectively. The parents are healthy second cousins. Other reported discordant cases of CDD are briefly reviewed.
authors.affiliation: Jahra Regional Liaison-Community Genetics Programme, Maternity Hospital, Kuwait.
authors.forename: T I
authors.initials: TI
authors.lastname: Farag
authors.forename: M A
authors.initials: MA
authors.lastname: Issa
authors.forename: E S
authors.initials: ES
authors.lastname: Mahfouz
mesh_terms: D003241:Consanguinity; D003964:Diaphragm / Q000002:abnormalities*; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D007231:Infant, Newborn; D008297:Male