[The effect of macrophages on the natural killer activity of the splenocytes of C3HA mice in the early stages of 20-methylcholanthrene-induced carcinogenesis].
The influence of macrophages on NK cell activity of C3HA mice on 1, 7 and 13 days after single i. m. injection of 20-methylcholanthren was investigated. It is shown that macrophages significantly stimulate this activity on the 13th day after carcinogen application.
Pogodina
O N
ON
Malygin
A M
AM
Goriunova
L B
LB
Fel'
V Ia
VIa
D000818:Animals; D002448:Cell Adhesion / Q000276:immunology; D002478:Cells, Cultured / Q000276:immunology; D003601:Cytotoxicity Tests, Immunologic; D007694:Killer Cells, Natural / Q000276:immunology*; D008264:Macrophages / Q000276:immunology*; D008297:Male; D008748:Methylcholanthrene / Q000633:toxicity*; D051379:Mice; D008809:Mice, Inbred C3H; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000276:immunology*; D013154:Spleen / Q000276:immunology*; D013997:Time Factors
D008748:Methylcholanthrene
Vliianie makrofagov na estestvennuiu killernuiu aktivnost' splenotsitov mysheĭ C3HA na rannikh stadiiakh kantserogeneza, vyzvannogo 20-metilkholantrenom.