title: MRI study of Baló's concentric sclerosis before and after immunosuppressive therapy.
abstract: An intra vitam diagnosis of Baló's concentric sclerosis in a 39-year-old male is described. To our knowledge this is the first reported case of ante-mortem diagnosis based solely on magnetic resonance imaging (MRI) findings. MRI showed features unique to this process. After high-dose intravenous therapy with prednisone, the clinical symptoms improved, and MRI showed marked changes of the concentric lesions.
authors.affiliation: Department of Neurology, University of Würzburg, Federal Republic of Germany.
authors.forename: M
authors.initials: M
authors.lastname: Spiegel
authors.forename: H
authors.initials: H
authors.lastname: Krüger
authors.forename: E
authors.initials: E
authors.lastname: Hofmann
authors.forename: L
authors.initials: L
authors.lastname: Kappos
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D007165:Immunosuppression Therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D011241:Prednisone / Q000627:therapeutic use*; D012598:Sclerosis / Q000175:diagnosis* / Q000628:therapy
chemical_list: D011241:Prednisone