title: Recurrent methemoglobinemia after acute dapsone intoxication in a child.
abstract: Dapsone is a synthetic sulfone increasingly used in the treatment of a wide variety of dermatologic disorders. The case of a child with dapsone-induced recurrent methemoglobinemia is presented with a discussion of dapsone toxicity and its treatment. In addition, the diagnostic value of pulse oximetry in the presence of dysfunctional hemoglobins is discussed.
authors.affiliation: Program in Clinical Toxicology, Children's Hospital, Harvard Medical School, Boston, Massachusetts.
authors.forename: J G
authors.initials: JG
authors.lastname: Linakis
authors.forename: M
authors.initials: M
authors.lastname: Shannon
authors.forename: A
authors.initials: A
authors.lastname: Woolf
authors.forename: C
authors.initials: C
authors.lastname: Sax
mesh_terms: D002675:Child, Preschool; D003622:Dapsone / Q000506:poisoning*; D005260:Female; D006801:Humans; D008708:Methemoglobinemia / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D008751:Methylene Blue / Q000627:therapeutic use; D012008:Recurrence
chemical_list: D003622:Dapsone; D008751:Methylene Blue