title: [Endogenous ethanol in the blood and tissues of rats with hypobaric hypoxia].
abstract: Albino male rats weighing 160-180 g were used to study the effect of short-term hypobaric hypoxia (ascent in an altitude chamber to 2500 m and 5000 m for 1 hr) on endogenous ethanol measured in blood, brain and liver; simultaneously enzymes responsible for ethanol and acetaldehyde metabolism were determined. Endogenous ethanol in blood and tissues was found to be a very sensitive marker of hypoxia which was not correlated with lactate, pyruvate, lipid peroxidation or 11-hydroxycorticosteroids. The latter parameters varied in response to severe hypoxia.
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Tarasov
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Ostrovskiĭ
authors.forename: V I
authors.initials: VI
authors.lastname: Satanovskaia
authors.forename: A V
authors.initials: AV
authors.lastname: Liopo
authors.forename: M G
authors.initials: MG
authors.lastname: Velichko
authors.forename: G Z
authors.initials: GZ
authors.lastname: Abakumov
mesh_terms: D000079:Acetaldehyde / Q000378:metabolism; D000426:Alcohol Dehydrogenase / Q000378:metabolism; D000444:Aldehyde Dehydrogenase / Q000378:metabolism; D000818:Animals; D001273:Atmosphere Exposure Chambers; D001921:Brain / Q000378:metabolism*; D000431:Ethanol / Q000097:blood / Q000378:metabolism*; D000860:Hypoxia / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008297:Male; D010100:Oxygen / Q000008:administration & dosage*; D051381:Rats
chemical_list: D000431:Ethanol; D000426:Alcohol Dehydrogenase; D000444:Aldehyde Dehydrogenase; D000079:Acetaldehyde; D010100:Oxygen
vernacular_title: Endogennyĭ étanol krovi i tkaneĭ krys pri gipobaricheskoĭ gipoksii.