HLA Bw57 and DR7 association with psoriasis vulgaris in south India.
Eighty-three south Indian patients with psoriasis vulgaris were studied for HLA antigen frequencies and compared with 77 controls studied simultaneously. HLA Bw57, a split of B17 was found elevated in the patients. The two sexes differed in their age-at-onset curves: females had a preponderance to early onset of the disease, while the males had late onset. Among these patients, major group 3, a Western Brachycephal Armenoid group, revealed the highest risk for B17 & Bw57 but not major group 2, a Mediterranean one.
Pitchappan
R M
RM
Unit of Immunogenetics, School of Biological Sciences, Madurai Kamaraj University, India.
Koteeswaran
A
A
Kakkaniah
V N
VN
Manickasundari
M
M
Rajaram
V
V
Muthuveeralakshmi
P
P
Mahendran
V
V
Brahmajothibai
V
V
D000328:Adult; D005260:Female; D015235:HLA-B Antigens / Q000032:analysis*; D015809:HLA-DR7 Antigen / Q000032:analysis*; D006801:Humans; D007194:India; D008297:Male; D010641:Phenotype; D011565:Psoriasis / Q000276:immunology*
D015235:HLA-B Antigens; C103707:HLA-B57 antigen; D015809:HLA-DR7 Antigen