Effect of defoliant (butiphose) on morpho-physiological properties and enzyme systems of natural membranes.
Butiphose (Tributyltritiophosphate, (C4H9S)3PO) a commonly used defoliant in cotton growing regions of USSR, caused extensive alterations in morphological features of erythrocyte and nuclear membranes and affected the permeability properties of rat liver mitochondrial membrane. It disrupted Ca2+ transport system and other energy dependent processes in mitochondria. A reduction in the activity of cytochrome-c-oxidase and NAD.H-oxidase was also observed.
Mirakhmedov
A K
AK
Ochilov
K R
KR
Sagatova
G A
GA
Khan
M Z
MZ
Khole
V
V
D000818:Animals; D002463:Cell Membrane Permeability / Q000187:drug effects; D004910:Erythrocyte Membrane / Q000187:drug effects*; D006540:Herbicides / Q000494:pharmacology*; D007425:Intracellular Membranes / Q000187:drug effects; D008297:Male; D008930:Mitochondria, Liver / Q000187:drug effects*; D009685:Nuclear Envelope / Q000187:drug effects*; D063086:Organothiophosphates / Q000494:pharmacology*; D009946:Organothiophosphorus Compounds / Q000494:pharmacology*; D011817:Rabbits; D051381:Rats
D006540:Herbicides; D063086:Organothiophosphates; D009946:Organothiophosphorus Compounds; C006863:butyl phosphorotrithioate