Evaluation of a casein and a whey hydrolysate for treatment of cow's-milk-sensitive enteropathy.
A casein and a whey hydrolysate were evaluated in the management of 18 children with cow's-milk-sensitive enteropathy. This diagnosis was based upon clinical features, an abnormal small intestinal mucosa, i.e. an enteropathy, and a clinical response to cow's milk elimination. Two infants refused to take the whey hydrolysate. The median weight gain was higher in children given whey hydrolysate (19.4 g/day) than the casein hydrolysate (9.8 g/day). All children responded to cow's milk elimination and most had a significant improvement in small intestinal morphology after a cow's-milk-free diet. There was some advantage for the whey hydrolysate on morphometric analysis of their small intestinal mucosal response.
Walker-Smith
J A
JA
Queen Elizabeth Hospital for Children, London, United Kingdom.
Digeon
B
B
Phillips
A D
AD
D000818:Animals; D002364:Caseins / Q000008:administration & dosage*; D005260:Female; D005512:Food Hypersensitivity / Q000178:diet therapy* / Q000209:etiology; D005526:Food, Formulated; D006801:Humans; D007223:Infant; D007410:Intestinal Diseases / Q000178:diet therapy* / Q000209:etiology / Q000473:pathology; D007413:Intestinal Mucosa / Q000473:pathology; D007421:Intestine, Small / Q000473:pathology; D008297:Male; D008892:Milk / Q000009:adverse effects*
D002364:Caseins