title: Changes in phase analysis patterns of radionuclide ventriculograms obtained from baboons during atrial pacing, septic shock, and induced myocardial infarction.
abstract: Changes in intraventricular phase delays, phase angle histograms, amplitude images, and electrocardiograms (ECG) were investigated during oesophageal pacing with and without beta-blockade, after induced myocardial infarction, and during septic shock in the anaesthetized baboon model. Unavoidable triggering from the pacemaker spike and to a lesser extent increased heart rate were responsible for parameter changes during pacing. Myocardial infarction changed contraction patterns, which did not always correlate with conduction changes from the ECG's. Cardiac volume changes during septic shock could be responsible for the abnormal trends in phase angle spread and electrocardiographic data.
authors.affiliation: AEC Institute for Life Sciences, Faculty of Medicine, University of Pretoria, South Africa.
authors.forename: I C
authors.initials: IC
authors.lastname: Dormehl
authors.forename: N
authors.initials: N
authors.lastname: Hugo
authors.forename: A L
authors.initials: AL
authors.lastname: van Gelder
authors.forename: M
authors.initials: M
authors.lastname: Maree
authors.forename: L
authors.initials: L
authors.lastname: Jacobs
authors.forename: J
authors.initials: J
authors.lastname: Davies
mesh_terms: D000818:Animals; D002304:Cardiac Pacing, Artificial; D002306:Cardiac Volume; D004562:Electrocardiography; D005583:Fourier Analysis; D006321:Heart / Q000000981:diagnostic imaging*; D008297:Male; D009203:Myocardial Infarction / Q000000981:diagnostic imaging*; D010215:Papio; D011433:Propranolol; D015635:Radionuclide Ventriculography; D012016:Reference Values; D012772:Shock, Septic / Q000000981:diagnostic imaging*
chemical_list: D011433:Propranolol