[Clinical and hematological profile of hemoglobin C Ziguinchor (Cz) in Western Africa].
The authors report 10 cases of Hb C Ziguinchor share out in 3 features ACz, SCz, Cz-PHHF (HPFH: hereditary persistence of foetal hemoglobin). The clinical and hematological study of the features has allowed the following conclusions: the Hb Cz is a rare mutant specific of the Negro and which original focus may be in Senegal. The heterozygote form (ACz) does not present any clinical manifestation. The association Hb S-Hb Cz brings about a serious hemoglobinopathy which has clinical and hematological features like the sickle cell disease (SS). The association Hb Cz-HPFH is relatively supported in spite of episodic painful crisis.
Sangare
A
A
Service d'Hématologie du Centre Hospitalier Universitaire de Cocody, Abidjan.
Fabritius
H
H
Sanogo
I
I
Kple-Faget
P
P
Sawadogo
S
S
Ambofo
Y
Y
D000293:Adolescent; D000328:Adult; D044383:Black People; D002648:Child; D005260:Female; D006444:Hemoglobin C / Q000235:genetics; D006453:Hemoglobinopathies / Q000097:blood* / Q000208:ethnology / Q000235:genetics; D006579:Heterozygote; D006801:Humans; D008297:Male; D010375:Pedigree; D012675:Senegal
C053485:hemoglobin C Ziguinchor; D006444:Hemoglobin C
Profil clinique et hématologique de l'hémoglobine C Ziguinchor (Cz) en Afrique Occidentale.