[Mechanisms of photodestruction of the eye structure. Formation of polypeptide aggregates upon UV-irradiation of lens proteins].
UV-light injury of individual crystallins (water soluble proteins of the cattle eye crystalline lens) were studied by SDS PSSG technique. Photodamage resulted in oligomer formation. The appearance of high molecular aggregates with the molecular mass as large as 10(5) D were seen in all fractions of the crystalline.
El'chaninov
V V
VV
Fedorovich
I B
IB
D000818:Animals; D002417:Cattle; D003459:Crystallins / Q000528:radiation effects*; D004591:Electrophoresis, Polyacrylamide Gel; D007908:Lens, Crystalline / Q000528:radiation effects*; D010455:Peptides / Q000378:metabolism*; D014466:Ultraviolet Rays
D003459:Crystallins; D010455:Peptides
Mekhanizmy fotopovrezhdeniia struktur glaza. Obrazovanie agregatov polipeptidov pri UF-obluchenii belkov khrustalika.