Effects of low-fat diets on gastric stress-induced ulcers after barbiturate administration in rats.
The effect of low-fat diets on appearance of stress-induced gastric ulcers was tested in rats consuming phenobarbital (0.25 ml/100g/day) during 1 week. The results showed a significant increase of the ulcerated area in the stomachs of the rats fed by low-fat diets, versus controls. It seemed that a diet adequate in lipids may decrease the ulcerogenic effects induced by chronic use of phenobarbital.
Seri
S
S
Aquilio
E
E
D'Alessandro
A
A
D000818:Animals; D004041:Dietary Fats / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D008297:Male; D010634:Phenobarbital / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D013276:Stomach Ulcer / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D013312:Stress, Physiological / Q000150:complications* / Q000503:physiopathology
D004041:Dietary Fats; D010634:Phenobarbital