[Radiation effects on expression of FC-receptor of alveolar macrophages of rat and their specific phagocytosis].
BCG-activated alveolar macrophages (AM) of Wistar rats were irradiated with different doses of gamma-ray in vitro. The effects of radiation on the expression of their Fc-receptor and specific phagocytic activity were observed. AM, after irradiation with doses of 0, 100, 300 and 500 Gy, showed decreasing phagocytic activity to chicken red blood cells (CRBC) opsonized with anti-CRBC antibody with no change in phagocytic indices. The expression of Fc-receptor of AM was, however, increased.
Hu
L P
LP
Gong
Y F
YF
Wu
D C
DC
D000818:Animals; D003037:Cobalt Radioisotopes; D008264:Macrophages / Q000528:radiation effects*; D008297:Male; D010587:Phagocytosis / Q000528:radiation effects*; D011650:Pulmonary Alveoli / Q000166:cytology; D051381:Rats; D011919:Rats, Inbred Strains; D011961:Receptors, Fc / Q000528:radiation effects*
D003037:Cobalt Radioisotopes; D011961:Receptors, Fc