title: Different pathways of DNA synthesis are operative in the fat body of Spodoptera litura (insecta) during larval and pupal development.
abstract: In Spodoptera litura, the DNA content of the fat body increases during the last larval instar. Radiolabelling studies reveal high degree of H3-thymidine incorporation in the fat cell DNA, during last larval stage of development. At prepupal stage the DNA synthesised during larval development is degraded, at least partially and the resultant nucleotides are most likely used as building blocks for the fat cell DNA synthesis during pupal development and pupal-adult metamorphosis, because very little H3 -thymidine injected into pupae is incorporated in DNA, though in fact, significant amount of DNA is synthesised during this period.
authors.affiliation: School of Life Sciences, University of Hyderabad, India.
authors.forename: A
authors.initials: A
authors.lastname: Dutta-Gupta
authors.forename: P
authors.initials: P
authors.lastname: Lakshmi
mesh_terms: D000818:Animals; D004247:DNA / Q000096:biosynthesis*; D005216:Fat Body / Q000378:metabolism*; D007814:Larva / Q000254:growth & development; D007915:Lepidoptera / Q000187:drug effects / Q000235:genetics* / Q000254:growth & development; D011679:Pupa / Q000235:genetics; D013936:Thymidine / Q000493:pharmacokinetics
chemical_list: D004247:DNA; D013936:Thymidine