title: The management of post-keratoplasty glaucoma by trabeculectomy.
abstract: The results of 35 consecutive trabeculectomies in eyes developing medically uncontrollable glaucoma following penetrating keratoplasty are presented, with a mean follow-up of 3 years from the time of drainage surgery. Five eyes remained phakic until trabeculectomy was performed. Additional medical therapy was necessary to control the intraocular pressure in 32 eyes, which therefore were considered to have failed to be controlled by trabeculectomy and 90% of these failed within 6 months of filtration surgery. Despite additional medical therapy, in 17 eyes, further drainage surgery was required and 90% of this surgery took place within the first 14 months. Adverse prognostic factors were multiple grafts and synechiae closure of the drainage angle.
authors.affiliation: Corneal Clinic, Moorfields Eye Hospital, London.
authors.forename: A M
authors.initials: AM
authors.lastname: Gilvarry
authors.forename: C M
authors.initials: CM
authors.lastname: Kirkness
authors.forename: A D
authors.initials: AD
authors.lastname: Steele
authors.forename: N S
authors.initials: NS
authors.lastname: Rice
authors.forename: L A
authors.initials: LA
authors.lastname: Ficker
mesh_terms: D000086:Acetazolamide / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction; D016009:Chi-Square Distribution; D004456:Echothiophate Iodide / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D015948:Keratoplasty, Penetrating / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010862:Pilocarpine / Q000627:therapeutic use; D011379:Prognosis; D012307:Risk Factors; D013999:Timolol / Q000627:therapeutic use; D014130:Trabeculectomy
chemical_list: D010862:Pilocarpine; D013999:Timolol; D004456:Echothiophate Iodide; D000086:Acetazolamide