title: Immunohistochemical analysis of accelerated graft atherosclerosis in cardiac transplantation.
abstract: HHT was performed between minimally genetic mismatched inbred strains of rats. There was no evidence of rejection and immunosuppressive therapy was not instituted. Immunohistochemical analysis using peroxidase conjugated monoclonal anti-rat ASMA of cardiac arterioles in which AGAS developed revealed a decreased peroxidase signal. The data suggest that modulation of actin expression in subintimal cells of cardiac arterioles may play a critical role in the pathologic development of AGAS.
authors.forename: H W
authors.initials: HW
authors.lastname: Louie
authors.forename: M
authors.initials: M
authors.lastname: Pang
authors.forename: W
authors.initials: W
authors.lastname: Lewis
authors.forename: D C
authors.initials: DC
authors.lastname: Drinkwater
authors.forename: H
authors.initials: H
authors.lastname: Laks
mesh_terms: D000818:Animals; D001160:Arterioles / Q000473:pathology; D003324:Coronary Artery Disease / Q000209:etiology* / Q000473:pathology; D003331:Coronary Vessels / Q000473:pathology; D016027:Heart Transplantation; D007150:Immunohistochemistry; D009131:Muscle, Smooth, Vascular / Q000276:immunology / Q000473:pathology; D009206:Myocardium / Q000473:pathology; D011183:Postoperative Complications / Q000209:etiology* / Q000473:pathology; D051381:Rats; D011916:Rats, Inbred F344; D011917:Rats, Inbred Lew; D016042:Transplantation, Heterotopic; D014654:Vascular Patency