title: Restoration of dysgenic murine (mdg) myotube contraction after addition of Schwann cells from normal mice in vitro.
abstract: Muscular dysgenesis in mutant mice is characterised by failure of excitation-contraction (E-C) coupling and consequent loss of skeletal muscle contraction. Contractile activity is restored in vitro by the addition of normal mice cells (11) (18) (7). In the present study we show a new model: contraction and ultrastructural organization of dysgenic myotubes are restored by coculture with Schwann cells from normal mice.
authors.affiliation: Laboratoire de Neurobiologie cellulaire, Université de Bordeaux II, URA-CNRS #1126, Talence, France.
authors.forename: P
authors.initials: P
authors.lastname: Courbin
authors.forename: A
authors.initials: A
authors.lastname: Do Thi
authors.forename: A
authors.initials: A
authors.lastname: Ressouches
authors.forename: C
authors.initials: C
authors.lastname: Dussartre
authors.forename: J A
authors.initials: JA
authors.lastname: Powell
authors.forename: J
authors.initials: J
authors.lastname: Koenig
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D051379:Mice; D008817:Mice, Mutant Strains; D009119:Muscle Contraction; D009132:Muscles / Q000166:cytology* / Q000502:physiology; D012583:Schwann Cells / Q000166:cytology* / Q000502:physiology