Ultrasound induced damages and time bound recovery in mouse liver.
Therapeutic ultrasound at 875 kHz at 10 and 15 W/cm2 intensity induced extensive damages in the liver of mouse. Total exposure of 5 min was spread over 5 days. Aqueous medium was avoided by coupling the transducer directly to the skin surface. Mild to extensive damages were noted. Complete distortion of hepatocellular architecture was noted in 15 W irradiated mice. However, there was almost complete recovery by 10th day following the last exposure.
Kumar
R P
RP
Raju
G S
GS
D000818:Animals; D008099:Liver / Q000033:anatomy & histology / Q000528:radiation effects*; D051379:Mice; D008815:Mice, Inbred Strains; D014464:Ultrasonic Therapy / Q000009:adverse effects*