title: [Circadian rhythm of reaction of epithelial cells of the tongue and esophagus to the effects of hydroxyurea].
abstract: A study was made of the effect of a single injection of hydroxyurea (HU) on the daily rhythm of labelling index (LI) in the epithelial cells of the tongue and esophagus. HU was injected 6 times a day. The degree of decrease in the LI at varying times of the day correlated well with the initial level of the LI. At the same time the number of sensitive cells changed thought the day in a different proportion than LI rhythm, the fact suggesting the independence of these rhythms.
authors.forename: V P
authors.initials: VP
authors.lastname: Rybakov
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Romanov
mesh_terms: D000818:Animals; D002455:Cell Division / Q000187:drug effects*; D002940:Circadian Rhythm; D004848:Epithelium / Q000187:drug effects; D004947:Esophagus / Q000187:drug effects*; D006918:Hydroxyurea / Q000494:pharmacology*; D008297:Male; D051379:Mice; D013997:Time Factors; D014059:Tongue / Q000187:drug effects*
chemical_list: D006918:Hydroxyurea
vernacular_title: Sutochnyĭ ritm reaktsii kletok épiteliia iazyka i pishchevoda mysheĭ na vozdeĭstvie oksimocheviny.