[Studies of thioamides and their derivatives. VIII. Products of decomposition of quaternary salts of 1-[alpha-alkylthio-p-dimethyl- amino)benzylidene]piperidine and 1-[alpha-alkylthio-(p-trialkyl- ammonio)benzylidene]piperidine].
Products of decomposition of eight quaternary salts, derivatives of 1-[alpha-alkylthio-(p-dimethylamino)benzylidene]-piperidinium, in water, ethanol, pyridine and glacial acetic acid were investigated. IR and UV spectra of the obtained decomposition products were measured, and the compounds were tested for cytostatic activity.
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D000577:Amides / Q000494:pharmacology*; D055598:Chemical Phenomena; D002621:Chemistry; D004355:Drug Stability; D006868:Hydrolysis; D066298:In Vitro Techniques; D008938:Mitosis / Q000187:drug effects*; D010880:Piperidines / Q000032:analysis / Q000494:pharmacology*; D013854:Thioamides / Q000032:analysis / Q000494:pharmacology*; D014908:Triticum / Q000166:cytology* / Q000187:drug effects
D000577:Amides; D010880:Piperidines; D013854:Thioamides
Badania w dziedzinie tioamidów i ich pochodnych. VIII. Produkty rozkładu czwartorzedowych soli 1-[alpha-alkilotio-(p-dimetyloamino)benzylideno]piperydyniowych I 1-[alpha-alkilotio-(p-trialkiloamonio)benzylideno]piperydyniowych.