Evaluation of several tests in screening for chloroquine maculopathy.
Patients receiving antimalarial therapy, specifically hydroxychloroquine, for different periods were evaluated using contrast sensitivity test (CST) and results were compared with those of electro-retinography (EOG), and pattern visual evoked potential (PVEP), and a matching age control group. The results indicated CST to be most sensitive of the evaluated techniques particularly in patients under 40 years old. In 44.4% of the cases CST revealed macular dysfunction of which the other two methods of examination were not capable. Our findings suggest the CST is a reliable and practical method which could be used as an additional screening test for chloroquine maculopathy.
Bishara
S A
SA
Department of Ophthalmology, Hadassah University Hospital, Jerusalem, Israel.
Matamoros
N
N
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015350:Contrast Sensitivity; D004585:Electrooculography; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000009:adverse effects*; D008266:Macula Lutea / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D010363:Pattern Recognition, Automated; D011237:Predictive Value of Tests; D011897:Random Allocation; D012164:Retinal Diseases / Q000139:chemically induced* / Q000175:diagnosis; D015351:Vision Screening / Q000379:methods*; D014792:Visual Acuity
D006886:Hydroxychloroquine