[Campylobacter pyloridis (Cp) infection of gastric mucosa in the high and low risk areas of gastric cancer in Liaoning province].
Gastric biopsies in 690 subjects from the high and low risk areas of gastric cancer were examined for identification of Cp in the gastric mucosa by Warthin-Starry, Gimenez and Gram's stains. The result showed that the positive rate was 60-62% in the high risk area whereas it was only 12.6% in the low risk area in Liaoning province. 81-85% of the positive subjects had active chronic gastritis including chronic superficial and atrophic gastritis. The result indicates a close correlation between the active chronic gastritis and Cp infection. Therefore, control of the Cp infection in the gastric mucosa is very important for lowering the incidence of chronic gastritis, a well known precursor of gastric cancer.
Lin
H Z
HZ
Cancer Institute, China University of Medical Sciences, Shenyang.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002167:Campylobacter / Q000302:isolation & purification; D002169:Campylobacter Infections / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology; D002681:China / Q000453:epidemiology; D005260:Female; D005753:Gastric Mucosa / Q000382:microbiology* / Q000473:pathology; D005756:Gastritis / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000209:etiology*