title: Hypocrellin-A sensitized photooxidation of bilirubin.
abstract: Hypocrellin A (HA) extracted from Hypocrellia bambusae (b.et Br.) sace, a derivative of 3,10-dihydroxy-4,9-perylenequinone, is a highly effective photosensitizer. Kinetic studies of the HA-sensitized photooxidation of bilirubin IX alpha (BR) in different solvents in the presence of various active oxygen quenchers indicate that in aprotic solvents the photooxidation goes via a Type II (1O2) mechanism, whereas in alkaline protic solvents Type I (electron transfer from an excited state of HA to the ground state of oxygen or the BR substrate). Type II and probably free radical reactions may occur simultaneously.
authors.forename: J S
authors.initials: JS
authors.lastname: Ma
authors.forename: F
authors.initials: F
authors.lastname: Yan
authors.forename: C Q
authors.initials: CQ
authors.lastname: Wang
authors.forename: J Y
authors.initials: JY
authors.lastname: An
mesh_terms: D001663:Bilirubin / Q000528:radiation effects*; D008027:Light; D010084:Oxidation-Reduction; D010569:Perylene / Q000031:analogs & derivatives*; D019800:Phenol; D011809:Quinones; D011838:Radiation-Sensitizing Agents; D013053:Spectrophotometry
chemical_list: D011809:Quinones; D011838:Radiation-Sensitizing Agents; D019800:Phenol; D010569:Perylene; C028529:photobilirubin; D001663:Bilirubin; C048388:hypocrellin A