title: [Prenatal diagnosis of a translocation (X;Y) and genetic counseling].
abstract: A cytogenetic prenatal diagnosis due to maternal age led us to find a male fetus with a (X;Y) translocation. This translocation is found in the mother, who presents no phenotypic abnormalities or mental retardation. The 22 cases described in the literature indicate that among male carriers of an (X;Y) translocation, half the cases present mental retardation and 2/3 phenotypic anomalies. These findings led us to give a genetic counselling of therapeutic abortion. Post mortem histological examination revealed no morphodysplasia.
authors.forename: H
authors.initials: H
authors.lastname: Stora-de Novion
authors.forename: C
authors.initials: C
authors.lastname: Petit
authors.forename: S
authors.initials: S
authors.lastname: Raynaud
authors.forename: N
authors.initials: N
authors.lastname: Ayraud
mesh_terms: D000032:Abortion, Therapeutic; D002869:Chromosome Aberrations / Q000175:diagnosis*; D002871:Chromosome Banding; D025063:Chromosome Disorders; D005817:Genetic Counseling; D006801:Humans; D011296:Prenatal Diagnosis; D014178:Translocation, Genetic; D014960:X Chromosome; D014998:Y Chromosome
vernacular_title: Dépistage prénatal d'une translocation (X;Y) et conseil génétique.