title: [The efficacy of the chemotherapy of patients with chronic destructive pulmonary tuberculosis].
abstract: The efficacy and tolerance of chemotherapy consisting of 4-6 drugs used intermittently and (or) daily for 3 to 16 months were determined in 100 patients with chronic destructive pulmonary tuberculosis formerly treated without effect. Discharge of Bacteria ceased in 71.4% of patients, the caverns healed in 22% and partially regressed in 67% that was correspondingly 33%, 10.8% and 12.6% higher than in routine regimens of chemotherapy used in 125 patient and consisted of three daily administered drugs. The time of abacillation and healing of the caverns in polychemotherapy were two months shorter. The tolerability of both regimens was satisfactory and approximately similar.
authors.forename: N I
authors.initials: NI
authors.lastname: Zakupra
authors.forename: V V
authors.initials: VV
authors.lastname: Khomenko
mesh_terms: D000995:Antitubercular Agents / Q000009:adverse effects / Q000627:therapeutic use*; D002908:Chronic Disease; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D004361:Drug Tolerance; D006801:Humans; D013997:Time Factors; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents
vernacular_title: Effektivnost' khimioterapii bol'nykh khronicheskim destruktivnym tuberkulezom legkikh.