[Determining the biological activity of levorin by the international standard of candicidin].
Levorin and candicidin represent close mixtures of heptaenic components. Their physicochemical and biological properties were also close. The antibiotics showed similar diffusive properties in their assay by the agar diffusion method. This made it possible to determine activity of the Soviet levorin standard by the International candicidin standard. For defining the levorin unit in the international units of candicidin, a scaling ratio of 9 was proposed.
Bo'lshakova
L O
LO
Shenin
Iu D
IuD
Fradkova
T A
TA
Ermolova
O B
OB
Astanina
L N
LN
Grigo'reva
V M
VM
D000362:Agar; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002174:Candicidin / Q000494:pharmacology* / Q000592:standards; D002175:Candida / Q000187:drug effects*; D003470:Culture Media; D004058:Diffusion; D004352:Drug Resistance, Microbial; D066298:In Vitro Techniques; D007394:International System of Units / Q000592:standards; D008826:Microbial Sensitivity Tests / Q000379:methods / Q000592:standards; D014586:USSR; D014944:World Health Organization
D000900:Anti-Bacterial Agents; D003470:Culture Media; D002174:Candicidin; D000362:Agar
Opredelenie biologicheskoĭ aktivnosti levorina po mezhdunarod- nomu standartu kanditsidina.