[The isolation and characteristics of antibiotic-containing liposomes].
The results of studies on the incorporation of a number of antibiotics into liposomes and the use of gamma irradiation for sterilization of phospholipid vesicles are presented. The toxicity of hydrochloride tetracyclin in free and liposomal forms is estimated for golden hamster with different methods of administration.
Rotov
K A
KA
Vasil'ev
V P
VP
Antonov
Iu V
IuV
D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D006224:Cricetinae; D004307:Dose-Response Relationship, Radiation; D004337:Drug Carriers; D005720:Gamma Rays; D007928:Lethal Dose 50; D008081:Liposomes / Q000302:isolation & purification* / Q000528:radiation effects; D008647:Mesocricetus; D013242:Sterilization; D013752:Tetracycline / Q000008:administration & dosage / Q000528:radiation effects / Q000633:toxicity
D000900:Anti-Bacterial Agents; D004337:Drug Carriers; D008081:Liposomes; D013752:Tetracycline
Poluchenie i kharakteristika liposom, soderzhashchikh antibiotiki.