title: Enterocyte ultrastructure and uptake of immunoglobulins in the small intestine of the neonatal lamb.
abstract: Although the small intestine of the sheep is relatively mature at birth, there are still vacuolated enterocytes present for at least 2 days in distal regions. In the distal regions, vacuolated cells possess a range of vesicle morphology which might be indicative of at least 2 separate routes for enterocyte handling of proteins taken up from the lumen. The localisation of immunoreactive immunoglobulins within the enterocytes, presumably of colostral or milk origin, in both proximal (non-vacuolated) and distal (vacuolated) regions, does not follow patterns which suggest orderly renewal at closure. It is suggested that closure is not solely brought about by epithelial cell replacement.
authors.affiliation: Department of Anatomy, University of Melbourne, Victoria, Australia.
authors.forename: J F
authors.initials: JF
authors.lastname: Trahair
authors.forename: P M
authors.initials: PM
authors.lastname: Robinson
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000033:anatomy & histology*; D007136:Immunoglobulins / Q000493:pharmacokinetics*; D007421:Intestine, Small / Q000378:metabolism / Q000648:ultrastructure*; D008854:Microscopy, Electron; D012756:Sheep / Q000033:anatomy & histology*
chemical_list: D007136:Immunoglobulins