[Pharmacologic properties of cholinoreceptor antibodies].
The study of pharmacological properties of cholinoreceptor antibodies is of definite interest due to the possibility of simulation of some myasthenic conditions. In 1986 the authors obtained antibodies by means of immunization of rabbits with antigenic material from skeletal muscles of the extremities of Balb/c mice. It was shown that incubation of the muscle with cholinoreceptor antibodies decreased its contraction under the effect of various concentrations of acetylcholine.
Burlakov
G V
GV
D000109:Acetylcholine / Q000276:immunology / Q000494:pharmacology; D000818:Animals; D000906:Antibodies / Q000032:analysis / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D007114:Immunization / Q000379:methods; D007865:Leeches / Q000187:drug effects / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D009119:Muscle Contraction / Q000187:drug effects / Q000276:immunology; D009121:Muscle Denervation; D009132:Muscles / Q000187:drug effects / Q000276:immunology; D011817:Rabbits; D011950:Receptors, Cholinergic / Q000187:drug effects / Q000276:immunology*; D013045:Species Specificity
D000906:Antibodies; D011950:Receptors, Cholinergic; D000109:Acetylcholine
Farmakologicheskie svoĭstva antikholinoretseptornykh antitel.