[Paroxysmal cold hemoglobinuria in a 2-year-old boy].
We report the case of a two-year-old boy, who presented with two episodes of severe abdominal pain and consecutive macrohematuria after he had been outside the house at very low temperatures. The cause of this was found to be acute hemolytic anemia with hemoglobinuria, induced by a cold reacting Donath-Landsteiner autoantibody. After a few days parameters of hemolysis had normalized, hemoglobin levels were within the normal range after 4 weeks. Eight months later the Donath-Landsteiner autoantibody could not be detected any more, the boy is healthy since then.
Bohnhorst
B
B
Abteilung Kinderheilkunde II, Kinderklinik der Medizinischen Hochschule, Hannover.
Krull
F
F
Hoyer
P F
PF
D000744:Anemia, Hemolytic, Autoimmune / Q000175:diagnosis / Q000276:immunology*; D001323:Autoantibodies / Q000032:analysis*; D002675:Child, Preschool; D003080:Cold Temperature / Q000009:adverse effects*; D004912:Erythrocytes / Q000276:immunology*; D006456:Hemoglobinuria / Q000276:immunology*; D006801:Humans; D008297:Male
D001323:Autoantibodies
Paroxysmale Kältehämoglobinurie bei einem 2jährigen Jungen.