title: [Histochemical study of the skeletal muscle in multiple sclerosis].
abstract: The authors present muscle histochemistry of ten patients of multiple sclerosis. The clinical diagnosis was based on criteria established by Poser et al. (1983). The main pathological findings observed were: lymphoplasmocitary vasculitis, increase in the number of 2B type fibers, inflammatory cells (macrophages) in the intramuscular ends of the motor nerves, amounts of lipids and 'moth-eaten' fibers. The presence of vasculitis observed in our cases contributes with the etiopathogenic hypothesis of an autoimmune lesion in multiple sclerosis. There is no correlation between the clinical and histological atrophy observed.
authors.affiliation: Disciplina de Neurologia da Faculdade de Ciências Médicas da Santa Casa de São Paulo, Brasil.
authors.forename: C P
authors.initials: CP
authors.lastname: Tilbery
authors.forename: M
authors.initials: M
authors.lastname: Atra
authors.forename: A S
authors.initials: AS
authors.lastname: Oliveira
authors.forename: L A
authors.initials: LA
authors.lastname: Calia
authors.forename: B
authors.initials: B
authors.lastname: Schmidt
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D050356:Lipid Metabolism; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D009132:Muscles / Q000473:pathology* / Q000503:physiopathology; D009133:Muscular Atrophy / Q000209:etiology; D012519:Sarcoplasmic Reticulum / Q000378:metabolism; D014657:Vasculitis / Q000209:etiology
vernacular_title: Estudo histoquímico do músculo esquelético na esclerose múltipla.