Human platelets contain mRNA transcripts for platelet factor 4 and actin.
RNAs from a number of cells, including platelets, were analyzed by Northern blotting for the presence of transcripts to four platelet proteins-actin, thrombospondin, fibronectin, and platelet factor 4. RNA from platelets contains considerable amounts of mRNA for platelet factor 4, easily detectable mRNA for actin, and traces of mRNA for thrombospondin. mRNA for platelet factor 4 was not detected in human lymphocytes or in any of 5 human cell lines.
Sottile
J
J
Department of Physiological Chemistry, University of Wisconsin, Madison 53706.
Mosher
D F
DF
Fullenweider
J
J
George
J N
JN
D000199:Actins / Q000235:genetics; D001792:Blood Platelets / Q000378:metabolism*; D015152:Blotting, Northern; D005353:Fibronectins / Q000235:genetics; D006801:Humans; D008562:Membrane Glycoproteins / Q000235:genetics; D010978:Platelet Factor 4 / Q000235:genetics*; D012333:RNA, Messenger / Q000097:blood*; D019699:Thrombospondins
D000199:Actins; D005353:Fibronectins; D008562:Membrane Glycoproteins; D012333:RNA, Messenger; D019699:Thrombospondins; D010978:Platelet Factor 4