Acute macular neuroretinopathy following intravenous sympathomimetics.
Three young women developed acute macular neuroretinopathy with persistent paracentral scotomas following acute hypertension caused by intravenous sympathomimetics. The temporal relationship of the acute onset of symptoms suggests either acute hypertension or a direct retinal effect of sympathomimetics as the cause of the retinal changes.
O'Brien
D M
DM
Department of Ophthalmology, University of Washington School of Medicine, Seattle 98195.
Farmer
S G
SG
Kalina
R E
RE
Leon
J A
JA
D000208:Acute Disease; D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D004809:Ephedrine / Q000008:administration & dosage / Q000009:adverse effects; D004837:Epinephrine / Q000008:administration & dosage / Q000009:adverse effects; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D007275:Injections, Intravenous; D008266:Macula Lutea / Q000187:drug effects*; D012164:Retinal Diseases / Q000139:chemically induced*; D012607:Scotoma / Q000139:chemically induced; D013566:Sympathomimetics / Q000008:administration & dosage / Q000009:adverse effects*
D013566:Sympathomimetics; D004809:Ephedrine; D004837:Epinephrine