title: Modification of the gerbil's taste behavior by the sucrose taste antagonist p-nitrophenyl alpha-D-glucopyranoside.
abstract: Since the gerbil's chorda tympani nerve response to sucrose is antagonized by p-nitrophenyl alpha-D-glucopyransoide (PNP-Glu), the present taste aversion behavioral experiments sought to determine whether the gerbil's behavioral gustatory responses could be modified by adding PNP-Glu to taste solutions. Results demonstrated that the gerbil's aversion to sucrose was affected by the addition of PNP-Glu, but that the avoidance was overcome by the addition of high enough concentrations of the antagonist. When mixtures of sucrose and quinine were tested, the gerbil's sucrose aversion was unaffected, nor was any change noted in the taste behavior of gerbils trained to avoid 0.1 M sodium chloride after the addition of PNP-Glu.
authors.affiliation: Department of Biological Sciences, Herbert H. Lehman College, Bronx, NY.
authors.forename: C E
authors.initials: CE
authors.lastname: Myers
authors.forename: A
authors.initials: A
authors.lastname: Neita
authors.forename: W
authors.initials: W
authors.lastname: Jakinovich
mesh_terms: D000818:Animals; D001362:Avoidance Learning / Q000502:physiology*; D004305:Dose-Response Relationship, Drug; D005247:Feeding Behavior / Q000187:drug effects*; D005518:Food Preferences / Q000187:drug effects*; D005849:Gerbillinae; D005960:Glucosides / Q000494:pharmacology*; D006027:Glycosides / Q000494:pharmacology*; D008297:Male; D011803:Quinine / Q000494:pharmacology*; D013395:Sucrose; D013649:Taste / Q000187:drug effects*
chemical_list: D005960:Glucosides; D006027:Glycosides; C019502:4-nitrophenyl alpha-glucoside; D013395:Sucrose; D011803:Quinine