title: [Synthesis of racemates and enantiomers of 3-alkylthalidomide analogs and determination of their absolute configuration].
abstract: The syntheses of the racemates and the enantiomers of the title compounds 7a-7c and of racem. 1,3-dimethyl-thalidomide (8) are reported. The absolute configuration of the optically active products is determined. The hypnotic activities of the analogs of thalidomide 7a - 7c and of the intermediates 6a - 6c are to be tested in animals.
authors.forename: J
authors.initials: J
authors.lastname: Knabe
authors.forename: G
authors.initials: G
authors.lastname: Omlor
mesh_terms: D055598:Chemical Phenomena; D002621:Chemistry; D008968:Molecular Conformation; D013237:Stereoisomerism; D013792:Thalidomide / Q000031:analogs & derivatives* / Q000138:chemical synthesis
chemical_list: D013792:Thalidomide
vernacular_title: Synthese der Racemate und der Enantiomere von 3-Alkylthalidomidanaloga und Bestimmung ihrer absoluten Konfiguration.