[Angiogenesis activity of tissues and cells of different malignancies].
Cancer cells are able to produce tumor angiogenesis factors (TAF), by which the tumor growth could be maintained. Angiogenetic activity of 12 kinds of cells and tissues with distinct character from different sources were detected by chick embryo chorioallantoic membrane. The results indicated that all the cells and tissues tested showed angiogenetic activity but they differed from one another, some were strong and other weak. Of them, the breast cancer was the strongest. The ascitic tumor didn't show any angiogenetic activity, but it reappeared when the ascitic cells were transformed to solid tumors. The level of angiogenetic activity of tumors was closely related to their biological properties and form of existence.
Jiang
Z G
ZG
Beijing Institute for Cancer Research.
D043925:Angiogenesis Inducing Agents / Q000032:analysis*; D000818:Animals; D001943:Breast Neoplasms / Q000032:analysis*; D002286:Carcinoma, Ehrlich Tumor / Q000032:analysis*; D002642:Chick Embryo; D003110:Colonic Neoplasms / Q000032:analysis; D006133:Growth Substances / Q000032:analysis*; D006801:Humans; D007938:Leukemia / Q000378:metabolism / Q000473:pathology; D051379:Mice; D008807:Mice, Inbred BALB C; D009368:Neoplasm Transplantation; D013274:Stomach Neoplasms / Q000032:analysis / Q000473:pathology; D014407:Tumor Cells, Cultured
D043925:Angiogenesis Inducing Agents; D006133:Growth Substances