New platelet aggregation inhibitors.
From a cultured broth of Streptomyces matensis A-6621, we isolated three new platelet aggregation inhibitors designated as PI-080, PI-085 and PI-087. The structures of these compounds were established by spectral and chemical methods.
Kawashima
A
A
Kishimura
Y
Y
Tamai
M
M
Hanada
K
K
D000818:Animals; D005285:Fermentation; D066298:In Vitro Techniques; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000302:isolation & purification* / Q000494:pharmacology; D011817:Rabbits; D013302:Streptomyces / Q000378:metabolism*
D010975:Platelet Aggregation Inhibitors