[Various indicators of the kallikrein-kinin system of the blood in patients of reproductive age with dysfunctional uterine hemorrhage].
Fifteen women with dysfunctional uterine hemorrhages [DUH] of the reproductive period and ten women aged 20 to 30 with normal two-phase menstrual cycle were examined. Measurements of the blood plasma kallikrein and prekallikrein activities in normal females have revealed a direct correlation between kallikrein level and colpocytologic data and an inverse correlation between prekallikrein level and these data. An incessant growth of kallikrein content was detected in DUH patients, whereas their prekallikrein levels were much lower than in the controls. A manifest activation of the kallikrein-kinin system was detected in the patients with DUH of the reproductive period, augmenting with the development of the proliferative processes in the endometrium.
Vodianik
N D
ND
Diugeev
A N
AN
Ivanova
T S
TS
D000328:Adult; D005260:Female; D006801:Humans; D007610:Kallikreins / Q000097:blood*; D008595:Menorrhagia / Q000201:enzymology / Q000503:physiopathology*; D008597:Menstrual Cycle / Q000502:physiology; D008875:Middle Aged; D011288:Prekallikrein / Q000032:analysis
D011288:Prekallikrein; D007610:Kallikreins
Sostoianie nekotorykh pokazateleĭ kallikrein-kininovoĭ sistemy krovi u bo'lnykh s disfunktsiona'lnymi matochnymi krovotecheniiami reproduktivnogo perioda.