[Studies of lysozyme activity in the saliva of workers in the drug industry].
The aim of this study was to examine the lysozyme activity in saliva of pharmaceutic industry workers in whom pathologic changes in the oral cavity were previously diagnosed. The study was carried out in the Pharmaceutic Plant "Polfa" in Stargard Gdański at the departments of sulphonamides, acetylsalicylic acid and various syntheses. The study comprised 94 workers from whom resting saliva samples were collected 2-3 hours after breakfast. The lysozyme activity was determined using the modified Litwack method, while proteins were examined using the Lawry method. Our examinations have demonstrated a higher enzyme activity in pharmaceutic industry workers as compared to the control group. The highest lysozyme activity was recorded at the sulphonamides department.
Zajaczkowska-Białowas
L
L
Z Zakładu Stomatologii Zachowawczej IS AM w Gdańsku.
Nowicka
J
J
Kuc
B
B
Sibora
P
P
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D004796:Clinical Enzyme Tests; D004345:Drug Industry; D004789:Enzyme Activation / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000139:chemically induced / Q000175:diagnosis* / Q000201:enzymology; D009113:Muramidase / Q000032:analysis / Q000378:metabolism*; D009784:Occupational Diseases / Q000139:chemically induced / Q000175:diagnosis* / Q000201:enzymology; D011044:Poland; D012463:Saliva / Q000201:enzymology*; D013449:Sulfonamides / Q000138:chemical synthesis / Q000633:toxicity*
D013449:Sulfonamides; D009113:Muramidase
Badania aktywności lizozymu w ślinie osób zatrudnionych w zakładach przemysłu farmaceutycznego.