title: [Diffuse meningeal melanoma].
abstract: Diffuse leptomeningeal melanoma is an uncommon condition; its diagnosis is difficult, and requires the detection of atypical melanic cells in the CSF or the performance of meningeal biopsy. We report a 34-year-old patient with progressive symptoms of intracranial hypertension of 2 months duration, in whom meningeal biopsy was required for a definitive diagnosis. The patient's age, the neuropathological abnormalities and the images of computed tomography scan (CT), and also a through clinical and paraclinical investigation, led us to the conclusion that the patient had diffuse primary leptomeningeal melanoma.
authors.forename: M
authors.initials: M
authors.lastname: Martínez
authors.forename: M
authors.initials: M
authors.lastname: Aguilar
authors.forename: M
authors.initials: M
authors.lastname: de Miguel
authors.forename: J
authors.initials: J
authors.lastname: Peres Serra
mesh_terms: D000328:Adult; D001706:Biopsy; D006801:Humans; D008297:Male; D008545:Melanoma / Q000473:pathology* / Q000503:physiopathology; D008577:Meningeal Neoplasms / Q000473:pathology* / Q000503:physiopathology
vernacular_title: Melanoma meníngeo difuso.