[Results of severe aplastic anemia treated with antilymphocytic globulin].
The best results of the therapeutic immunosuppression in a plastic anemia have been obtained with antilymphocyte globulin (ALG). Considering this, 14 patients with this disease, 9 females and 5 males, from 8 to 60 years of age, were given ALG (40 mg/K/day/4 days) and corticosteroids. Fifty one percent of them, older than 30 years of age, showed partial or minimal remissions of the disorder. According to this result ALG administration together with bone-marrow transplantation in younger patients may offer effective treatment for a generally fatal disease to a greater number of patients.
Morales-Polanco
M R
MR
Pizzuto-Chávez
J
J
Izquierdo-Ramírez
J
J
Farfán-Canto
J M
JM
D000293:Adolescent; D000328:Adult; D000741:Anemia, Aplastic / Q000188:drug therapy*; D000961:Antilymphocyte Serum / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012074:Remission Induction
D000961:Antilymphocyte Serum
Resultados del tratamiento de la anemia aplástica grave con globulina antilinfocitaria.