title: HLA Bw57 and DR7 association with psoriasis vulgaris in south India.
abstract: Eighty-three south Indian patients with psoriasis vulgaris were studied for HLA antigen frequencies and compared with 77 controls studied simultaneously. HLA Bw57, a split of B17 was found elevated in the patients. The two sexes differed in their age-at-onset curves: females had a preponderance to early onset of the disease, while the males had late onset. Among these patients, major group 3, a Western Brachycephal Armenoid group, revealed the highest risk for B17 & Bw57 but not major group 2, a Mediterranean one.
authors.affiliation: Unit of Immunogenetics, School of Biological Sciences, Madurai Kamaraj University, India.
authors.forename: R M
authors.initials: RM
authors.lastname: Pitchappan
authors.forename: A
authors.initials: A
authors.lastname: Koteeswaran
authors.forename: V N
authors.initials: VN
authors.lastname: Kakkaniah
authors.forename: M
authors.initials: M
authors.lastname: Manickasundari
authors.forename: V
authors.initials: V
authors.lastname: Rajaram
authors.forename: P
authors.initials: P
authors.lastname: Muthuveeralakshmi
authors.forename: V
authors.initials: V
authors.lastname: Mahendran
authors.forename: V
authors.initials: V
authors.lastname: Brahmajothibai
mesh_terms: D000328:Adult; D005260:Female; D015235:HLA-B Antigens / Q000032:analysis*; D015809:HLA-DR7 Antigen / Q000032:analysis*; D006801:Humans; D007194:India; D008297:Male; D010641:Phenotype; D011565:Psoriasis / Q000276:immunology*
chemical_list: D015235:HLA-B Antigens; C103707:HLA-B57 antigen; D015809:HLA-DR7 Antigen