title: Non-apatitic environments in bone mineral: FT-IR detection, biological properties and changes in several disease states.
abstract: Resolution enhanced FT-IR spectroscopy shows that non-apatitic environments of phosphate and carbonate ions occur in bone mineral. The spectroscopic characteristics of these environments and their chemical and biological properties are reviewed. The potential effectiveness of FT-IR for the detailed study of bone mineral changes in bone disease is shown by analysis of several samples.
authors.affiliation: Laboratory for the Study of Skeletal Disorders, Children's Hospital, Harvard Medical School, Boston, MA.
authors.forename: C
authors.initials: C
authors.lastname: Rey
authors.forename: J
authors.initials: J
authors.lastname: Lian
authors.forename: M
authors.initials: M
authors.lastname: Grynpas
authors.forename: F
authors.initials: F
authors.lastname: Shapiro
authors.forename: L
authors.initials: L
authors.lastname: Zylberberg
authors.forename: M J
authors.initials: MJ
authors.lastname: Glimcher
mesh_terms: D000818:Animals; D001031:Apatites; D015519:Bone Density; D001847:Bone Diseases / Q000378:metabolism*; D002254:Carbonates / Q000032:analysis*; D005399:Fishes; D005458:Fluoride Poisoning / Q000378:metabolism; D006801:Humans; D010710:Phosphates / Q000032:analysis* / Q000097:blood; D013055:Spectrophotometry, Infrared / Q000379:methods; D014808:Vitamin D Deficiency / Q000378:metabolism
chemical_list: D001031:Apatites; D002254:Carbonates; D010710:Phosphates