[Study on transdermal absorption of borneol-salicylic acid eutectic mixture].
Borneol is an organic drug having property to form eutectic mixture with salicylic acid. We compared the transdermal absorption rate of borneol alone with that of borneol-salicylic acid eutectic mixture in hairless rats. The results showed that the borneol-salicylic acid eutectic mixture can evidently increase the absorption rate of borneol and provided a method for manufacturing borneol preparation which can easily be absorbed transdermally.
Cui
D X
DX
Sugibayashi
K
K
Morimoto
Y
Y
Li
F L
FL
D000818:Animals; D001892:Camphanes / Q000008:administration & dosage / Q000493:pharmacokinetics*; D004338:Drug Combinations; D051381:Rats; D012459:Salicylates / Q000008:administration & dosage / Q000493:pharmacokinetics*; D012869:Skin Absorption; D012995:Solubility
D001892:Camphanes; D004338:Drug Combinations; D012459:Salicylates; C022871:isoborneol