title: Wound healing. Oral and topical activity of Aloe vera.
abstract: The influence of Aloe vera, orally and topically, on wound healing was studied. Wounds were induced on both sides of the vertebral column of ICR mice using a biopsy punch. For the oral study, experimental animals received A. vera in their drinking water for 2 months, whereas the control animals received only water. In the topical study, experimental animals were given 25% A. vera in Eucerin cream topically. The control animals received cream only. A 62.5% reduction in wound diameter was noted in mice receiving 100 mg/kg/day oral A. vera and a 50.8% reduction was recorded in animals receiving topical 25% A. vera. These data suggest that A. vera is effective by both oral and topical routes of administration.
authors.forename: R H
authors.initials: RH
authors.lastname: Davis
authors.forename: M G
authors.initials: MG
authors.lastname: Leitner
authors.forename: J M
authors.initials: JM
authors.lastname: Russo
authors.forename: M E
authors.initials: ME
authors.lastname: Byrne
mesh_terms: D000284:Administration, Oral; D000287:Administration, Topical; D000504:Aloe; D000818:Animals; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D010946:Plants, Medicinal; D014945:Wound Healing / Q000187:drug effects*; D014947:Wounds and Injuries / Q000188:drug therapy* / Q000473:pathology