Recurrent methemoglobinemia after acute dapsone intoxication in a child.
Dapsone is a synthetic sulfone increasingly used in the treatment of a wide variety of dermatologic disorders. The case of a child with dapsone-induced recurrent methemoglobinemia is presented with a discussion of dapsone toxicity and its treatment. In addition, the diagnostic value of pulse oximetry in the presence of dysfunctional hemoglobins is discussed.
Linakis
J G
JG
Program in Clinical Toxicology, Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Shannon
M
M
Woolf
A
A
Sax
C
C
D002675:Child, Preschool; D003622:Dapsone / Q000506:poisoning*; D005260:Female; D006801:Humans; D008708:Methemoglobinemia / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D008751:Methylene Blue / Q000627:therapeutic use; D012008:Recurrence
D003622:Dapsone; D008751:Methylene Blue