Human in vitro fertilization in couples with unexplained infertility and a poor postcoital test.
The results of in vitro fertilization (IVF) with the husband's semen were compared in 3 groups of fully investigated infertile couples. In those with tubal infertility (n = 43) 194 out of 273 (71.1%) oocytes were fertilized, at least 1 oocyte being fertilized in 42 of the 43 couples (97%). In couples with unexplained infertility and a 'good' postcoital test (PCT) (n = 9), 39 out of 64 (61.5%) oocytes were fertilized in 8 of the 9 (88%) couples. In couples with unexplained infertility and a 'poor positive' PCT despite normal semen analysis, 16 out of 44 (36.3%) oocytes were fertilized in 5 of the 6 (83%) couples. These results show a good correlation between in vivo sperm penetration of cervical mucus and human IVF in couples with unexplained infertility.
Balasch
J
J
Department of Obstetrics and Gynecology, Hospital Clínic i Provincial, Barcelona, Spain.
Jové
I
I
Ballescá
J L
JL
Moreno
V
V
Mulet
J
J
Fuster
J
J
Vanrell
J A
JA
D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000503:physiopathology*; D007248:Infertility, Male / Q000503:physiopathology*; D008297:Male; D012661:Semen / Q000032:analysis*; D013084:Sperm-Ovum Interactions / Q000502:physiology*