Ovulation following combined therapy with wen-jing-tang and clomiphene citrate therapy in anovulatory women.
The effect of combined therapy with Wen-Jing-Tang and clomiphene citrate on anovulation was studied in 16 infertile patients who did not respond to clomiphene citrate alone. Wen-Jing-Tang was given at a dose of 5 g a day every day from day 2 of the menstrual cycles and clomiphene citrate was given at 150 mg a day for 5 days from day 5 of the cycle. Ovulation occurred in 43.8% of the patients and 48.6% of the cycles. No case of ovarian hyperstimulation syndrome or pregnancy were observed. These results suggest that the combined therapy with Wen-Jing-Tang and clomiphene citrate should be used before therapy with human menopausal gonadotropin.
Yoshimoto
Y
Y
Department of Obstetrics and Gynecology, Osaka University Medical School, Japan.
Miyake
A
A
Tasaka
K
K
Aono
T
T
Tanizawa
O
O
D000328:Adult; D000858:Anovulation / Q000188:drug therapy*; D002996:Clomiphene / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D010060:Ovulation / Q000187:drug effects*
D004365:Drugs, Chinese Herbal; D002996:Clomiphene