title: Antinuclear antibodies in psoriatic arthritis and its subgroups.
abstract: We tested serum samples from 48 patients with Psoriatic Arthritis (PA) for Antinuclear Antibodies (ANA) using a highly sensitive substrate (Hep-2 cells). We obtained the following results: 1) in PA patients ANA positivity (16.6%) was significantly higher than in age-and sex-matched groups of healthy controls (4.1%; p less than 0.05) and uncomplicated psoriasis (2%; p less than 0.025). 2) ANA were more common in Symmetrical Polyarthritis (37.5%) and Arthritis Mutilans (25%) than in Asymmetrical Oligoarthritis and Spondarthritis (11.8%) and 'Classical' PA (0%). 3) We did not find any positivity for anti-DNA and anti-ENA antibodies among PA patients.
authors.affiliation: Department of Dermatology, Spedali Civil, Brescia, Italy.
authors.forename: P G
authors.initials: PG
authors.lastname: Calzavara
authors.forename: R
authors.initials: R
authors.lastname: Cattaneo
authors.forename: F
authors.initials: F
authors.lastname: Franceschini
authors.forename: C
authors.initials: C
authors.lastname: Tosoni
authors.forename: M
authors.initials: M
authors.lastname: Martinelli
authors.forename: A
authors.initials: A
authors.lastname: Carlino
mesh_terms: D000328:Adult; D000368:Aged; D000974:Antibodies, Antinuclear / Q000032:analysis*; D015535:Arthritis, Psoriatic / Q000145:classification / Q000276:immunology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D000974:Antibodies, Antinuclear