title: [Functional and biochemical reorganization in hyperfunction of the dopaminergic system].
abstract: In dogs, cats, rabbits, the effects of unique and chronic administration of L-DOPA (20-50 mg/kg daily) on central dopamine processes, behaviour, interrelations of sensory and motor regimens of the structures and on the transmitter metabolism, were studied. The interrelations of sensory and motor regimens became competitive, reciprocal changes occurred in dopaminergic and other transmitter (serotoninergic and acetylcholinergic) systems. The findings seem to be related to development of psychomotor excitation.
authors.forename: N S
authors.initials: NS
authors.lastname: Popova
authors.forename: E L
authors.initials: EL
authors.lastname: Dovedova
authors.forename: R
authors.initials: R
authors.lastname: Veskova
authors.forename: B
authors.initials: B
authors.lastname: Jankovic
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism; D000661:Amphetamine / Q000494:pharmacology; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000201:enzymology / Q000502:physiology; D002415:Cats; D004285:Dogs; D004569:Electroencephalography; D004924:Escape Reaction / Q000187:drug effects / Q000502:physiology; D005074:Evoked Potentials, Visual / Q000187:drug effects / Q000502:physiology; D007980:Levodopa / Q000494:pharmacology; D008995:Monoamine Oxidase / Q000378:metabolism; D011817:Rabbits; D011954:Receptors, Dopamine / Q000187:drug effects / Q000502:physiology*
chemical_list: D011954:Receptors, Dopamine; D007980:Levodopa; D000661:Amphetamine; D008995:Monoamine Oxidase; D000110:Acetylcholinesterase
vernacular_title: Funktsional'nye i biokhimicheskie perestroĭki v usloviiakh giperfunkttsii dofaminergicheskoĭ sistemy.