[The effectiveness of treating patients with malignant skin lymphoma and Kaposi's sarcoma studied via polyamines].
Lymphoproliferative diseases of the skin and Kaposi's sarcoma were found to involve high excretion of polyamines. Therapy with reaferon combined with prospidine and indomethacin improved the clinical course of the process and was associated with a decrease of polyamine excretion. Measurement of the urine polyamines may be used for the assessment of the treatment efficacy in malignant lymphomas of the skin and in Kaposi's sarcoma.
Faradzhev
Z G
ZG
Samsonov
V A
VA
Bassalyk
L S
LS
Nemtsova
M P
MP
D000293:Adolescent; D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002908:Chronic Disease; D004341:Drug Evaluation; D006801:Humans; D007213:Indomethacin / Q000008:administration & dosage; D007370:Interferon Type I / Q000008:administration & dosage; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D008223:Lymphoma / Q000188:drug therapy* / Q000652:urine; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000188:drug therapy / Q000652:urine; D011073:Polyamines / Q000652:urine*; D011239:Prednisolone / Q000008:administration & dosage; D011447:Prospidium / Q000008:administration & dosage; D011994:Recombinant Proteins; D012514:Sarcoma, Kaposi / Q000188:drug therapy* / Q000652:urine; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000652:urine; D014750:Vincristine / Q000008:administration & dosage
D007370:Interferon Type I; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011073:Polyamines; D011994:Recombinant Proteins; D014750:Vincristine; D011447:Prospidium; D011239:Prednisolone; D007213:Indomethacin
Izuchenie éffektivnosti lecheniia bol'nykh zlokachestvennymi limfomami kozhi i sarkomoĭ Kaposhi s pomoshch'iu poliaminov.