title: Horizontal transmission in sheep and delayed clearance in guinea pigs and mice of a Brucella melitensis Rev. I mutant.
abstract: Virulence assays in guinea-pigs, mice and sheep with a Rev. I mutant strain (FSA) demonstrated that the latter had increased virulence in comparison with a reference strain. The mutant showed slower clearance in guinea-pigs and mice when compared with standard Rev. I strains and horizontal transmission was achieved in 2 sheep.
authors.affiliation: Veterinary Research Institute, Onderstepoort, Republic of South Africa.
authors.forename: P
authors.initials: P
authors.lastname: Hunter
authors.forename: S M
authors.initials: SM
authors.lastname: Pefanis
authors.forename: C C
authors.initials: CC
authors.lastname: Williamson
authors.forename: W J
authors.initials: WJ
authors.lastname: Botha
authors.forename: M S
authors.initials: MS
authors.lastname: Van Schalkwyk
mesh_terms: D000818:Animals; D002002:Brucella / Q000472:pathogenicity*; D005260:Female; D006168:Guinea Pigs; D051379:Mice; D009154:Mutation; D011247:Pregnancy; D012756:Sheep; D014774:Virulence