[Determining the conditions for stimulation of levorin biosynthesis in the presence of succinic acid].
Conditions promoting the stimulating effect of succinic acid on biosynthesis of levorin were determined. The optimal concentration of succinate was shown to be equal to 0.05-0.3 per cent and the best time for the addition was before inoculation. The most pronounced stimulating effect was observed when the initial pH value of the fermentation medium was equal to 7.0. The important role of ammonium nitrogen in manifestation of the succinic acid stimulating effect on biosynthesis of levorin was suggested.
Ku'zmin
V N
VN
Tsyganov
V A
VA
D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D002174:Candicidin / Q000096:biosynthesis*; D003470:Culture Media; D005285:Fermentation; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D013268:Stimulation, Chemical; D013302:Streptomyces / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D013386:Succinates / Q000494:pharmacology*; D019802:Succinic Acid
D000900:Anti-Bacterial Agents; D003470:Culture Media; D013386:Succinates; D002174:Candicidin; D019802:Succinic Acid
Vyiavlenie usloviĭ dlia stimuliatsii biosinteza levorina v prisutstvii iantarnoĭ kisloty.