[In vitro susceptibility of dermatophyte strains to imidazole derivatives].
Recently, imidazole derivatives are being successfully used for the dermatomycoses. These drugs have the strongest antimycotic activity. 44 dermatophyte strains were isolated from our out-patient with dermatomycosis. Imidazole derivatives such as isoconazole, oxiconazole, bifonazole and tioconazole were studied their efficacy on these fungal agents in vitro. 4 imidazole derivatives were effective on all of the dermatophyte strains in less than or equal to 5 micrograms/ml concentration. Whereas, there were differences in Minimal Inhibition Concentration (MIC) and MIC50 values.
Bozkurt
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Gazi Universitesi, Tip Fakültesi, Dermatoloji Anabilim Dali, Oğretim Uyesi.
Kuştimur
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Gürer
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D000935:Antifungal Agents / Q000494:pharmacology; D003883:Arthrodermataceae / Q000187:drug effects*; D003881:Dermatomycoses / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D007093:Imidazoles / Q000494:pharmacology* / Q000627:therapeutic use; D008825:Miconazole / Q000031:analogs & derivatives / Q000494:pharmacology
D000935:Antifungal Agents; D007093:Imidazoles; D008825:Miconazole; C022155:oxiconazole; C020382:isoconazole; C036596:bifonazole; C020527:tioconazole
Dermatofit suşlarinin imidazol türevlerine karşi invitro duyarliliği.