title: [Systemic candidiasis in children with cancer].
abstract: Systemic fungal infections have long been recognized in terminally ill patients with cancer. Systemic candidiasis is the most common, the incidence having increased in the last few years. Eight children diagnosed as having systemic candidiasis during a two-year period (1987-1988) are presented. Three had an isolated fungal pneumonitis, two an hepatosplenic candidiasis, one a multisystemic involvement (hepatosplenic, pulmonary and nodular skin lesions) and the remaining two patients had a Candida sepsis with no visceral lesions having been documented. All patients had neutropenia and prolonged fever no responsive to broad spectrum antibiotics. We would like to underline the importance of an early and prolonged antifungal therapy, especially in hepatosplenic candidiasis, in order to obtain the cure.
authors.affiliation: Unidad de Oncología, Ciudad sanitaria La Fe Hospital Infantil, Valencia.
authors.forename: J M
authors.initials: JM
authors.lastname: Fernández Navarro
authors.forename: A
authors.initials: A
authors.lastname: Verdeguer Miralles
authors.forename: J G
authors.initials: JG
authors.lastname: Ruiz Soler
authors.forename: J
authors.initials: J
authors.lastname: Ferris Tortajada
authors.forename: C
authors.initials: C
authors.lastname: Esquembre Menor
authors.forename: V
authors.initials: V
authors.lastname: Castel Sánchez
mesh_terms: D002177:Candidiasis / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000150:complications; D009369:Neoplasms / Q000150:complications*; D009503:Neutropenia / Q000150:complications; D009894:Opportunistic Infections / Q000209:etiology
vernacular_title: Candidiasis sistémicas en niños con cáncer.