[Production of lincomycin by Micromonospora halophytica culture].
A Micromonospara culture designated as 991/78 with activity against gram-positive cocci and bacteria was isolated from samples of silt-covered substrates from the Amu-Darya. Directed screening on a selective medium supplemented with lincomycin in an amount of 50-100 micrograms/ml was used. Identification of the antibiotic produced by the culture showed it to be lincomycin. By its taxonomic features the culture was classified as belonging to Micromonospora (subgroup II, Cinnamomea) and in particular to M. halophytica (Weinstein, Luedemann, Oden, Wagman, 1968). Up to now, it was known that lincomycin was produced only by Streptomyces cultures.
Bibikova
M V
MV
Singal
E M
EM
Ivanitskaia
L P
LP
Zhdanovich
Iu V
IuV
D000362:Agar; D002244:Carbon; D003470:Culture Media; D066298:In Vitro Techniques; D008034:Lincomycin / Q000096:biosynthesis* / Q000302:isolation & purification; D008847:Micromonospora / Q000254:growth & development / Q000378:metabolism*
D003470:Culture Media; D002244:Carbon; D000362:Agar; D008034:Lincomycin
Obrazovanie antibiotika linkomitsina ku'lturoĭ Micromonospora halophytica.