title: Neurofollicular hamartoma: a light microscopic and immunohistochemical study.
abstract: Neurofollicular hamartoma is an unusual, previously undescribed neoplasm characterized by a proliferation of spindle cells and hyperplastic pilosebaceous units. Five cases were reviewed. The lesions presented as single, asymptomatic, smooth, flesh-colored papules. Four were on the nose, and one on the adjacent nasolabial fold. Immunoperoxidase studies performed on two cases utilizing antibodies to S-100 antigen were positive in both. These lesions share some histological and clinical features with angiofibroma and neurofibroma.
authors.affiliation: Department of Dermatology, University of California, Irvine.
authors.forename: R J
authors.initials: RJ
authors.lastname: Barr
authors.forename: M M
authors.initials: MM
authors.lastname: Goodman
mesh_terms: D000328:Adult; D000368:Aged; D005153:Facial Neoplasms / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006222:Hamartoma / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009669:Nose Neoplasms / Q000378:metabolism / Q000473:pathology*; D009418:S100 Proteins / Q000378:metabolism; D012878:Skin Neoplasms / Q000378:metabolism / Q000473:pathology*
chemical_list: D009418:S100 Proteins