[A method for choosing preparations that alter hemoglobin binding to oxygen].
A simple method for investigating drug effect on hemoglobin oxygen affinity by the estimation of HbO2 (%) in blood with and without drugs after gas mixture saturation (4% O2, 5% CO2, 91% N2) is proposed.
Plotnikov
M B
MB
Laptev
B I
BI
Plotnikova
T M
TM
D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008722:Methods; D010100:Oxygen / Q000097:blood; D010108:Oxyhemoglobins / Q000378:metabolism*; D010313:Partial Pressure; D010889:Piracetam / Q000494:pharmacology*; D011485:Protein Binding / Q000187:drug effects / Q000502:physiology; D011760:Pyrrolidinones / Q000494:pharmacology*
D010108:Oxyhemoglobins; D011760:Pyrrolidinones; D001205:Ascorbic Acid; D010100:Oxygen; D010889:Piracetam
Metod otbora preparatov, izmeniaiushchikh sviazvanie gemoglobina s kislorodom.