[Clinical assessment of immunoglobulin E in the blood and the level of circulating immune complexes in parasitic diseases. 3. Opisthorchiasis].
45 patients with Opisthorchis felineus infection, 8 in the acute and 37 in the chronic stage of the disease of moderate severity or mild course were treated with praziquantel dosed 25-60 mg per kilo for one-day course. Only in 4 out of 45 patients egg output was more than 1000 per gram of feces (Kato-Katz method). Blood hypereosinophilia, elevated serum IgE and CIC content (215 +/- 56 against 76 +/- 19 in control) in the acute and the tendency to elevation of IgE content with the chronic opisthorchiasis before treatment were found. Tolerance of the treatment was satisfactory. Six-eight months later in patients with acute opisthorchiasis the content of serum IgE was significantly lower but still three times higher than normal. The other parameters in both groups of patients were normal.
Legon'kov
Iu A
IuA
Ovsiannikova
I G
IG
Ozeretskovskaia
N N
NN
Gervazieva
V B
VB
Bronshteĭn
A M
AM
D000293:Adolescent; D000328:Adult; D000936:Antigen-Antibody Complex / Q000032:analysis*; D004802:Eosinophilia / Q000188:drug therapy / Q000276:immunology; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D009889:Opisthorchiasis / Q000188:drug therapy / Q000276:immunology*; D010272:Parasitic Diseases / Q000276:immunology*; D011223:Praziquantel / Q000627:therapeutic use; D013997:Time Factors
D000936:Antigen-Antibody Complex; D007073:Immunoglobulin E; D011223:Praziquantel
Klinicheskaia ostenka immunoglobulinemii E i urovnia tsirkuliruiushchikh kompleksov pri parazitarnykh bolezniakh. Soobshchenie 3. Opistorkhoz.