[Observation on the distribution of [14C] AT-1902 in mice].
Distribution of [14C] AT-1902 in mice was studied by means of whole body autoradiography. After [14C] AT-1902 was injected im to mice, radioactivity was rapidly taken up by various organs. The highest radioactivity was found in kidneys, then the liver, lung, tumor and skin etc. Lowest radioactivity was found in brain. It is suggested that [14C] AT-1902 may be excreted through the gastrointestinal tract and kidneys.
Wang
Q D
QD
Hua
H Y
HY
Li
Q T
QT
Zhang
T M
TM
Zhang
X
X
Ren
Y F
YF
D000818:Animals; D000970:Antineoplastic Agents; D001345:Autoradiography; D005998:Glycine / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D006834:Hydrazines / Q000493:pharmacokinetics*; D008297:Male; D051379:Mice; D014018:Tissue Distribution; D014407:Tumor Cells, Cultured / Q000378:metabolism*
D000970:Antineoplastic Agents; D006834:Hydrazines; C062816:AT 1902; D005998:Glycine