title: Interleukin-1 beta stimulates the release of vasopressin from rat neurohypophysis.
abstract: The release of vasopressin from the isolated superfused rat neurohypophysis was measured. The electrically evoked release of vasopressin after phasic submaximal stimulation was increased on exposure to the cytokine, interleukin-1 beta (44 pM). The release returned to its control level when the peptide was withdrawn. The results indicates a permissive role of interleukin-1 beta in the release of vasopressin.
authors.affiliation: Department of Biology, Royal Danish School of Pharmacy, Copenhagen O.
authors.forename: J D
authors.initials: JD
authors.lastname: Christensen
authors.forename: E W
authors.initials: EW
authors.lastname: Hansen
authors.forename: B
authors.initials: B
authors.lastname: Fjalland
mesh_terms: D000818:Animals; D001127:Arginine Vasopressin / Q000378:metabolism; D004558:Electric Stimulation; D007375:Interleukin-1 / Q000494:pharmacology*; D007457:Iodine Radioisotopes; D008297:Male; D010904:Pituitary Gland, Posterior / Q000187:drug effects / Q000378:metabolism*; D011863:Radioimmunoassay; D051381:Rats; D011919:Rats, Inbred Strains; D014667:Vasopressins / Q000378:metabolism*
chemical_list: D007375:Interleukin-1; D007457:Iodine Radioisotopes; D014667:Vasopressins; D001127:Arginine Vasopressin