Electrophoretic study of proteins associated with pseudo-exfoliation syndrome.
Lens capsule and aqueous humour from cataractous eyes with and without pseudo-exfoliation syndrome have been studied by SDS-PAGE electrophoresis. Four cataractous lenses with and four without pseudo-exfoliation were used. The pseudo-exfoliation positive capsule revealed two polypeptides not present in the control material, and accordingly, these components were regarded to be pseudo-exfoliation specific. The molecular weight of the respective polypeptides was estimated to be 14,400 and 16,300. No marked differences were found between the pseudo-exfoliation positive and negative aqueous humours.
Ringvold
A
A
Department of Ophthalmology, University of Oslo, Norway.
Husby
G
G
Pettersen
S
S
D001082:Aqueous Humor / Q000378:metabolism*; D002386:Cataract / Q000150:complications / Q000378:metabolism; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007903:Lens Capsule, Crystalline / Q000378:metabolism*; D007905:Lens Diseases / Q000150:complications / Q000378:metabolism*; D007908:Lens, Crystalline / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism*
D011506:Proteins