[The morphofunctional status of the blood during the experimental intravenous administration of ultradispersed ferromagnetic particles].
In experiments on rats it has been shown that a single infusion of ultradispersed ferromagnetic particles (size from 0.2 to 1 micron) in a dose of 50 mg/kg leads to an increase in hemoglobin level, red blood cell and leucocyte content, to a growth of blood coagulation time and plasma fibrinolytic activity in the animals' blood, as well as to a rise in the level of neutrophil phagocytic reactions. A single infusion of magnetite particles of similar size, in a dose of 50 mg/kg, was not attended by the above changes, except for an increase in the neutrophil functional activity.
Volkonskiĭ
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VA
D000818:Animals; D001769:Blood / Q000187:drug effects*; D001773:Blood Cells / Q000187:drug effects* / Q000502:physiology; D001790:Blood Physiological Phenomena; D002214:Capsules; D005290:Ferric Compounds / Q000008:administration & dosage*; D052203:Ferrosoferric Oxide; D007275:Injections, Intravenous; D007501:Iron / Q000008:administration & dosage; D008297:Male; D010087:Oxides; D010316:Particle Size; D051381:Rats; D013997:Time Factors
D002214:Capsules; D005290:Ferric Compounds; D010087:Oxides; C001215:ferrite; D007501:Iron; D052203:Ferrosoferric Oxide
Morfofunktsional'nyĭ status krovi pri vnutrivennom vvedenii ul'tradispersnykh ferromagnitnykh chastits v éksperimente.