[A radioimmunologic method based on anti-idiotypic antibodies for detecting the hepatitis B surface antigen].
The antigen-independent radioimmunoassay for the detection of HBsAg is presented. The principle of this method is the inhibition of the reaction of binding idiotype antibodies and tracer anti-idiotype antibodies by the competing HBsAg. The antigen-independent competition radioimmunoassay is specific and has 80-100 ng/ml-1 of HBsAg sensitivity.
Kholodniuk
I D
ID
Kukaĭn
R A
RA
D000818:Animals; D000888:Antibodies, Anti-Idiotypic / Q000276:immunology*; D001667:Binding, Competitive; D006168:Guinea Pigs; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006801:Humans; D011817:Rabbits; D011863:Radioimmunoassay
D000888:Antibodies, Anti-Idiotypic; D006514:Hepatitis B Surface Antigens
Radioimmunologicheskiĭ metod na osnove antiidiotipicheskikh antitel dliia vyiavleniia poverkhnostnogo antigena virusa gepatita B.