[3 years' experience of radiation therapy with fast neutrons on the V-120 cyclotron].
The paper discusses the results of treatment of 128 patients with head and neck cancer in whom fast neutrons (Y-120; approximately 6.2 MeV) were used as a single procedure or in combination with surgery. Tumors of different histomorphologic structure displayed unequal sensitivity to fast neutrons. Mean disease-free survival in patients with complete regression of tumor was 24 months following neutron therapy alone, 18.5 months after combined neutron-photon treatment and 5.5 months only in controls. Relapse rates were 20 and 15% in patients with pre- and postoperative neutron treatment, respectively, as compared to 52% in controls.
Zyrianov
B N
BN
Musabaeva
L I
LI
Lisin
V A
VA
Lavrenkov
K A
KA
Kitsmaniuk
Z D
ZD
D000230:Adenocarcinoma / Q000532:radiotherapy; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D005069:Evaluation Studies as Topic; D005214:Fast Neutrons / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006258:Head and Neck Neoplasms / Q000532:radiotherapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D009502:Neutrons / Q000627:therapeutic use*; D010315:Particle Accelerators; D011827:Radiation; D011879:Radiotherapy Dosage; D012062:Relative Biological Effectiveness
Trekhletniĭ opyt luchevoĭ terapii bystrymi netronami na tsiklotrone V-120.