[Studies on the effects of 1,2-dichloroethane on reproductive function].
The results of the studies showed that the gonadotoxicity and embryotoxicity were found in rodents exposed to concentration of DCE at 24.8 mg/m3; DCE could reach the fetus through the placenta. The investigation of workers exposed to DCE indicated that prematurities among exposed female workers and wives of exposed male workers were higher than that of control groups. Therefore the MAC of DCE (25 mg/m3) is not safe enough.
Zhao
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D000818:Animals; D000831:Animals, Newborn; D004000:Dichloroethylenes / Q000506:poisoning* / Q000633:toxicity; D005260:Female; D005835:Genitalia / Q000187:drug effects; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000506:poisoning*; D008297:Male; D008452:Maximum Allowable Concentration; D051379:Mice; D007752:Obstetric Labor, Premature / Q000139:chemically induced; D009784:Occupational Diseases / Q000139:chemically induced; D011247:Pregnancy; D051381:Rats; D012098:Reproduction / Q000187:drug effects*
D004000:Dichloroethylenes; D006843:Hydrocarbons, Chlorinated; C035384:1,2-dichloroethylene