title: Clinical and therapeutic monitoring of epilepsy in a mental handicap unit.
abstract: Within a group of hospitals for the mentally handicapped serving the Leicestershire district, a cohort of 215 epileptic patients was identified, who were followed up for four years. The anticonvulsant medication of each patient was reviewed regularly until an optimal balance between seizure control, absence of medication side-effects, and reduction of polypharmacy was attained. After four years 172 patients remained in the study. A significant reduction in polypharmacy was attained overall. Some groups of patients showed a significant reduction in the frequency of seizures, while a small group of patients with frequent seizures remained difficult to control.
authors.affiliation: Department of Psychiatry, University of Leicester.
authors.forename: R A
authors.initials: RA
authors.lastname: Collacott
authors.forename: A
authors.initials: A
authors.lastname: Dignon
authors.forename: A
authors.initials: A
authors.lastname: Hauck
authors.forename: J W
authors.initials: JW
authors.lastname: Ward
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage*; D015331:Cohort Studies; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D004827:Epilepsy / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008607:Intellectual Disability / Q000188:drug therapy*; D008297:Male
chemical_list: D000927:Anticonvulsants