[Dipivefrin: its mechanism of action, clinical efficacy and good tolerance].
Dipivefrin (DPE) is the first prodrug in general use in ophthalmology. We will discuss the metabolism of DPE to epinephrine within the eye, and the efficacy and safety of DPE in the treatment of elevated intraocular pressure. In addition, we will address the incidence of adverse systemic effects, ocular tolerance and allergy, and the ocular hypotensive efficacy when DPE is used alone or in combination with other antiglaucoma medications.
Harper
D G
DG
Novack
G D
GD
Borrmann
L R
LR
Branin
M J
MJ
D004837:Epinephrine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D005901:Glaucoma / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D014792:Visual Acuity / Q000187:drug effects
C015173:dipivefrin; D004837:Epinephrine
Dipivéfrine, son mécanisme d'action, son efficacité clinique, sa bonne tolérance.