[Preliminary studies of the effect of steroid hormones on skin bacteria in vitro].
It results from studies on skin hormones that some of steroid hormones reach high concentrations on skin surface mainly during a course of acne vulgaris. Our studies indicate that the activity of hormones on skin bacteria can be multiform. Nineteen hormones of analytical grade of purity were tested. They were derived from different firms of synthesized in the Department of Endocrinology of the Pharmacology Institute of Polish Academy of Sciences in Cracow. Bacterial strains tested in this study were isolated from normal skin flora. The majority of the compounds tested in this study showed different reactivity toward Staphylococcus aureus as well as Staphylococcus epidermidis and anaerobic diphtheroids+ and sometimes aerobic ones.
Basta
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D000731:Androstanes / Q000494:pharmacology*; D000736:Androstenes / Q000494:pharmacology; D003352:Corynebacterium / Q000187:drug effects* / Q000254:growth & development; D003864:Depression, Chemical; D045166:Estradiol Congeners / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D011374:Progesterone / Q000494:pharmacology*; D045167:Progesterone Congeners / Q000494:pharmacology; D011424:Propionibacterium / Q000187:drug effects* / Q000254:growth & development; D012867:Skin / Q000382:microbiology*; D013210:Staphylococcus / Q000187:drug effects* / Q000254:growth & development; D013268:Stimulation, Chemical
D000731:Androstanes; D000736:Androstenes; D045166:Estradiol Congeners; D045167:Progesterone Congeners; D011374:Progesterone
Wstepne badania wpływu hormonów sterydowych in vitro na bakterie skórne.