title: [Effects of prospidin on the development of pulmonary metastases of Lewis tumors in rats in regard to changes in the level of extracellular calcium].
abstract: The effect of prospidin on Lewis lung carcinoma spreading under hyper- and hypocalcemia was studied. At early stages, increased extracellular calcium level was associated with inhibition of tumor dissemination to the lungs; however, later, colony growth was stimulated. Extracellular calcium level was shown to modulate the antitumor and antimetastatic effect of prospidin.
authors.forename: A S
authors.initials: AS
authors.lastname: Kinzirskiĭ
authors.forename: V A
authors.initials: VA
authors.lastname: Chernov
authors.forename: L M
authors.initials: LM
authors.lastname: Shapovalova
authors.forename: Z I
authors.initials: ZI
authors.lastname: Galochkina
authors.forename: L L
authors.initials: LL
authors.lastname: Mikhaĭlevskaia
authors.forename: N N
authors.initials: NN
authors.lastname: Surovenkova
mesh_terms: D000230:Adenocarcinoma / Q000097:blood / Q000556:secondary*; D000818:Animals; D002118:Calcium / Q000097:blood*; D008175:Lung Neoplasms / Q000097:blood / Q000556:secondary*; D051379:Mice; D008810:Mice, Inbred C57BL; D010879:Piperazines / Q000494:pharmacology*; D011447:Prospidium / Q000494:pharmacology*
chemical_list: D010879:Piperazines; D011447:Prospidium; D002118:Calcium
vernacular_title: Vliianie prospidina na razvitie legochnykh metastazov opukholi L'iuis na fone izmeneniia urovnia vnekletochnogo kal'tsiia.