Breast carcinoma metastatic to a meningioma. Case report and review of the literature.
We describe a patient who developed an intracranial mass that consisted of a meningioma and metastatic breast cancer. A literature review revealed 12 similar cases. In epidemiologic studies, the incidence of meningioma in patients with breast cancer is higher than expected. Both tumors are more common in women, have been reported to flare during pregnancy, and express hormone receptors. In a patient with breast cancer, an intracranial mass with radiographic features suggestive, but atypical, of a meningioma should be evaluated surgically. The lesion may represent a metastasis, a meningioma, or both.
Zon
L I
LI
Division of Medical Oncology, Dana-Farber Cancer Institute, Boston.
Johns
W D
WD
Stomper
P C
PC
Kaplan
W D
WD
Connolly
J L
JL
Morris
J H
JH
Harris
J R
JR
Henderson
I C
IC
Skarin
A T
AT
D001859:Bone Neoplasms / Q000556:secondary; D001932:Brain Neoplasms / Q000473:pathology / Q000556:secondary*; D001943:Breast Neoplasms / Q000473:pathology; D002277:Carcinoma / Q000556:secondary*; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000473:pathology / Q000556:secondary*; D008579:Meningioma / Q000473:pathology*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000473:pathology*