[Effect of dopamine on left-ventricular systolic time interval in children after open-heart surgery].
Effect of dopamine at the dose of 3 and 6 micrograms/kg/min on the systolic time intervals (STI) in 16 children after open heart surgery has been examined. The basic hemodynamic parameters --heart rate, systolic, diastolic and mean blood pressure have also been evaluated. Heart rate did not change during either rate of dopamine infusion. Systolic, diastolic and mean blood pressure increased significantly during the higher dose of dopamine. The dose of 3 and 6 micrograms/kg/min of dopamine decreased significantly the relation between pre-ejection period (PEP) and left-ventricular++ ejection time (LVET). Besides during the higher rate of infusion pre-ejection period index was decreased. The simple and noninvasive measurement of systolic time intervals is a sensitive index of the inotropic effect of dopamine in children after cardiac surgery.
Kruszyński
Z
Z
Podstawska
D
D
Wojciechowska
D
D
Wojtalik
M
M
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004298:Dopamine / Q000494:pharmacology*; D006334:Heart Function Tests; D006343:Heart Septal Defects / Q000503:physiopathology* / Q000601:surgery; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D007223:Infant; D009200:Myocardial Contraction / Q000502:physiology*; D011184:Postoperative Period; D011666:Pulmonary Valve Stenosis / Q000503:physiopathology* / Q000601:surgery; D013268:Stimulation, Chemical; D013599:Systole / Q000187:drug effects / Q000502:physiology*
D004298:Dopamine
Wpływ dopaminy na podokresy skurczu lewej komory u dzieci po zabiegach na otwartym sercu.