[Children of insulin-dependent diabetic patients. A determination of status].
We report on 143 newborns of mothers with insulin dependent diabetes during pregnancy. The mean birth weight was 3.091 (+/- 619) g at a mean gestational age of 38.4 (+/- 2) weeks. Neonatal morbidity was associated with the disease class, insulin levels in the amniotic fluid, urine and cord blood; and especially persistent fetal hyperinsulinism as indicated by repeatedly high amniotic fluid insulin levels during pregnancy. One infant died (neonatal mortality 0.69%) of a severe cardiac malformation combined with a caudal regression syndrome. This was the only major malformation in the group.
Schwingshandl
J
J
Universitäts-Kinderklinik, Graz.
Rosegger
H
H
Haas
J
J
Hofmann
H M
HM
Weiss
P A
PA
D000653:Amniotic Fluid / Q000378:metabolism; D001034:Apgar Score; D001724:Birth Weight; D001786:Blood Glucose / Q000378:metabolism*; D000013:Congenital Abnormalities / Q000097:blood; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007328:Insulin / Q000097:blood*; D008431:Maternal-Fetal Exchange; D007752:Obstetric Labor, Premature / Q000097:blood; D011247:Pregnancy; D011256:Pregnancy Outcome; D011254:Pregnancy in Diabetics / Q000097:blood*; D012307:Risk Factors
D001786:Blood Glucose; D007328:Insulin
Kinder insulinpflichtiger Diabetikerinnen. Eine Standortbestimmung.