[Significance of EEG findings in administering anticonvulsant drugs to adults with compensated epilepsy which began in childhood].
Significance of EEG findings for prognosis of further development in paroxysm is evaluated in this work in adult epileptic patients suffering from seizures which appeared in their childhood. The assessment is based on EEG made during the active phase of the disease and in the time when fits were compensated. Seizureless condition after discontinued medication was observed only in a group of patients with secondary type of epilepsy. We suppose these patients should remain under control since two thirds of them showed diffuse nonspecific changes, which means 50% risk of recurrence of seizures after discontinuation of drug therapy. When medication continued, 55% of patients remained without any fits, of this number in 21.6% seizures recurred on the average within seven years after experimental discontinuation of drug therapy in spite of frequently normal EEG findings. The fact that the group of compensated patients without medication did not include those with primarily generalized seizures can be explained by their good conditions observed even in their childhood and for this reason most of them were not treated in the Anti-Paroxysmal Centre.
Chromová
L
L
Fiedlerová
D
D
Dernerová
M
M
Spacek
M
M
D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage* / Q000627:therapeutic use; D004569:Electroencephalography / Q000187:drug effects; D004827:Epilepsy / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D000927:Anticonvulsants
Význam EEG nálezů pri rízení lécby antikonvulzivy u kompenzovaných dospĕlých epileptiků se záchvaty vzniklými v dĕtství.