A community outbreak of group A beta haemolytic streptococci with transferable resistance to erythromycin.
Erythromycin resistance amongst group A streptococci (GAS) in Great Britain is a relatively rare occurrence and outbreaks have been sporadically reported. Over an 8-month period in 1986 ten associated cases occurred in the town of Bridgewater in Somerset. Isolates were group A, type M4 and resistant to erythromycin (MIC 8 mg/l) but sensitive to lincomycin and clindamycin. Erythromycin resistance was transferable from all isolates to a group A recipient strain. No plasmid DNA could be detected in the original isolates or transconjugants.
Scott
R J
RJ
Public Health Laboratory, Musgrove Park Hospital, Taunton, Somerset.
Naidoo
J
J
Lightfoot
N F
NF
George
R C
RC
D000328:Adult; D002648:Child; D002675:Child, Preschool; D003227:Conjugation, Genetic; D004196:Disease Outbreaks; D004352:Drug Resistance, Microbial / Q000235:genetics; D004739:England; D004917:Erythromycin / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012574:Schools; D013290:Streptococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000235:genetics / Q000302:isolation & purification
D004917:Erythromycin