title: [A case of ankylosing spondylitis complicating Crohn's disease].
abstract: A 20-year-old man, who had suffered from ankylosing spondylitis for about 1 year, was admitted to our hospital due to melena and syncope. Physical examination revealed tenderness of abdomen and sacroiliac joint, and decreased spinal mobility. X-ray examination showed sacroiliitis and squaring of vertebral bodies. RA test and RAHA, negative; CRP, strongly positive; HLA-B 27 positive. Intestinal barium enema revealed skipping longitudinal fissure at terminal ileum, and a biopsy specimen of the colon revealed non-caseating granuloma. The association of ankylosing spondylitis and Crohn's disease has widely been known in Europe and United States; but this is the first case reported in detail in Japan, where incidences of both diseases were much lower than those found in Caucasians.
authors.forename: R
authors.initials: R
authors.lastname: Tanosaki
authors.forename: H
authors.initials: H
authors.lastname: Yamada
authors.forename: M
authors.initials: M
authors.lastname: Akizuki
authors.forename: H
authors.initials: H
authors.lastname: Asakura
authors.forename: N
authors.initials: N
authors.lastname: Chino
authors.forename: Y
authors.initials: Y
authors.lastname: Ichikawa
authors.forename: M
authors.initials: M
authors.lastname: Tashiro
authors.forename: H
authors.initials: H
authors.lastname: Iri
authors.forename: M
authors.initials: M
authors.lastname: Homma
mesh_terms: D000328:Adult; D003424:Crohn Disease / Q000150:complications* / Q000453:epidemiology; D015796:HLA-B27 Antigen / Q000032:analysis; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D013167:Spondylitis, Ankylosing / Q000150:complications* / Q000453:epidemiology / Q000276:immunology
chemical_list: D015796:HLA-B27 Antigen