31P magnetic resonance spectroscopy of the normal human brain: approaches using four dimensional chemical shift imaging and phase mapping techniques.
The use of four-dimensional chemical shift imaging to monitor phosphorus metabolites within the human brain is illustrated. Saturation effects are described, and acquisition conditions are discussed in relation to quantification and sensitivity. The effects of magnetic field variations on spectral parameters are assessed and the use of a field mapping technique is illustrated.
Coutts
G A
GA
Picker Research Laboratory, GEC Research, Wembley, London, UK.
Bryant
D J
DJ
Collins
A G
AG
Cox
I J
IJ
Sargentoni
J
J
Gadian
D G
DG
D000328:Adult; D001921:Brain / Q000033:anatomy & histology* / Q000378:metabolism; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008875:Middle Aged