An in vitro method for longitudinal evaluation of toxicity of endodontic sealers.
An in vitro method for longitudinal evaluation of root canal sealers was developed and applied. A newly introduced cell culture chamber was used to evaluate the cytotoxic effects of test samples immediately after mixing and for an extended period of time thereafter. A ranking of the test materials, based on their cytotoxicity, was allowed by the method.
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D000818:Animals; D002478:Cells, Cultured; D015194:Diffusion Chambers, Culture; D005347:Fibroblasts / Q000187:drug effects; D066298:In Vitro Techniques; D008422:Materials Testing / Q000379:methods; D051379:Mice; D012387:Root Canal Filling Materials / Q000633:toxicity*
D012387:Root Canal Filling Materials