title: Saccharin.
abstract: Saccharin, a nonnutritive sweetener discovered in 1879, has been the subject of controversy concerning its effect on public health on several occasions during this century. Over this period, the substance has come to be regarded as a useful commodity in the dietary management of diabetes mellitus. We review the historical and scientific background on the subject and propose a new approach in making public-health decisions on unique foods that serve a special dietary purpose.
authors.affiliation: Center for Food Safety and Applied Nutrition, Food and Drug Administration, Washington, DC 20204.
authors.forename: S A
authors.initials: SA
authors.lastname: Miller
authors.forename: V P
authors.initials: VP
authors.lastname: Frattali
mesh_terms: D000818:Animals; D002273:Carcinogens; D003927:Diet, Diabetic; D006801:Humans; D007880:Legislation, Drug; D012439:Saccharin / Q000633:toxicity; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D002273:Carcinogens; D012439:Saccharin