title: Blastocystis hominis: phylogenetic affinities determined by rRNA sequence comparison.
abstract: In 1912 Blastocystis hominis was identified as a new species and classified as a yeast (Brumpt 1912). In the early 1920s several groups confirmed its classification as a yeast, specifically a member of the genus Schizosaccharomyces (discussed by Zierdt et al. 1967). Apart from an occasional case report, the classification of B. hominis and its role as a harmless intestinal yeast was not questioned for another 50 years. Then, Zierdt (1967) suggested that it should be classified in the phylum Protozoa, subphylum Sporozoa, and that it should be considered as a potential pathogen. The likely role of B. hominis as a human pathogen has recently become more firmly established (Garcia et al. 1984; Sheehan et al. 1986) and its classification has been changed. Although the classification of B. hominis as a protozoon was assumed widely, classification as a sporozoon was not accepted, and the most recent definitive classification of the Protozoa did not even list B. hominis (Lee et al. 1985). Then, based essentially on a review of the known characteristics of the organism, it was recently reclassified into the subphylum Sarcodina (Zierdt 1988). Clearly, the phylogeny of this emerging human pathogen needs definitive analysis (Mehlhorn 1988).
authors.affiliation: Department of Clinical Microbiology, Flinders University of South Australia School of Medicine, Bedford Park.
authors.forename: A M
authors.initials: AM
authors.lastname: Johnson
authors.forename: A
authors.initials: A
authors.lastname: Thanou
authors.forename: P F
authors.initials: PF
authors.lastname: Boreham
authors.forename: P R
authors.initials: PR
authors.lastname: Baverstock
mesh_terms: D000818:Animals; D001483:Base Sequence; D056890:Eukaryota / Q000145:classification* / Q000235:genetics; D008969:Molecular Sequence Data; D009253:Naegleria / Q000235:genetics; D010802:Phylogeny; D012335:RNA, Ribosomal / Q000235:genetics*; D012441:Saccharomyces cerevisiae / Q000235:genetics; D012689:Sequence Homology, Nucleic Acid; D014122:Toxoplasma / Q000235:genetics
chemical_list: D012335:RNA, Ribosomal