title: Clinical evaluation of ketotifen syrup on atopic dermatitis: a comparative multicenter double-blind study of ketotifen and clemastine.
abstract: A double-blind comparative study was performed to investigate the usefulness of ketotifen syrup as compared with clemastine syrup in 284 patients with atopic dermatitis. The clinical efficacy of ketotifen was significantly superior to that of clemastine. Ketotifen alleviated not only pruritus but also other dermatologic symptoms.
authors.affiliation: Department of Dermatology, Nagasaki University, School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Yoshida
authors.forename: M
authors.initials: M
authors.lastname: Niimura
authors.forename: H
authors.initials: H
authors.lastname: Ueda
authors.forename: S
authors.initials: S
authors.lastname: Imaura
authors.forename: S
authors.initials: S
authors.lastname: Yamamoto
authors.forename: A
authors.initials: A
authors.lastname: Kukita
mesh_terms: D002974:Clemastine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003876:Dermatitis, Atopic / Q000188:drug therapy*; D004311:Double-Blind Method; D006801:Humans; D007665:Ketotifen / Q000627:therapeutic use*; D011759:Pyrrolidines / Q000627:therapeutic use*
chemical_list: D011759:Pyrrolidines; D002974:Clemastine; D007665:Ketotifen