Hypertension is not a complication in cyclosporine-A monotherapy.
The course of blood pressure and antihypertensive treatment (AHT) was studied in 27 renal transplant recipients immunosuppressed with cyclosporine-A (CyA) as monotherapy. At the time of transplantation 13 patients received AHT and 14 were normotensive. The final outcome of transplantation and CyA immunosuppression was 19 patients without AHT, 4 with reduced AHT and 3 with unchanged doses of AHT, while in 1 case a de novo mild hypertension necessitated diuretic treatment.
Hansen
B L
BL
Department of Nephrology, Cardiac and Vascular Surgery, University Hospital of Odense, Denmark.
Rohr
N
N
Svendsen
V
V
Birkeland
S A
SA
D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D003524:Cyclosporins / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006973:Hypertension / Q000139:chemically induced*; D007165:Immunosuppression Therapy; D016030:Kidney Transplantation; D008297:Male
D000959:Antihypertensive Agents; D003524:Cyclosporins