Incidence of hemoglobins S and C in infants born in Miami to recent Haitian immigrants.
The incidence of hemoglobins S and C was determined for infants born to mothers who had recently emigrated to Miami from Haiti. The rates for hemoglobin S trait was 8.0% and C trait 4.7%. These values were higher than those found for American Blacks studied during the same period. Rates for those homozygous for hemoglobin S and doubly heterozygous for hemoglobins S and C are also reported but due to the infrequency with which they occur, the rates are less reliable. These data demonstrate that these abnormal hemoglobins occur in a significant number of Haitians and implies the existence of a considerable number of individuals with sickle cell anemia and hemoglobin SC disease in that country. It is important that a definitive study be done in Haiti to more precisely quantitate the magnitude of the problem so that appropriate health care strategies can be developed.
Pegelow
C H
CH
Department of Pediatrics, University of Miami School of Medicine, Florida.
Mack
A K
AK
D044383:Black People; D005260:Female; D005431:Florida; D006205:Haiti / Q000453:epidemiology / Q000208:ethnology; D006444:Hemoglobin C / Q000032:analysis*; D006450:Hemoglobin SC Disease / Q000150:complications / Q000453:epidemiology; D006451:Hemoglobin, Sickle / Q000032:analysis*; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D008297:Male; D014481:United States / Q000453:epidemiology; D001741:Black or African American
D006451:Hemoglobin, Sickle; D006444:Hemoglobin C