title: Endogenous factors contributing to prosthetic device infections.
abstract: Although there is a direct association between the tissue reactivity of implants and their ability to potentiate infection, bacterial slime production and adherence to implant surfaces (generation of the biofilm) appear to play a primary role in the pathogenesis of most prosthesis infections.
authors.affiliation: Department of Surgery, Texas Tech University, El Paso.
authors.forename: S H
authors.initials: SH
authors.lastname: Dougherty
authors.forename: R L
authors.initials: RL
authors.lastname: Simmons
mesh_terms: D001419:Bacteria / Q000378:metabolism; D001422:Bacterial Adhesion; D001424:Bacterial Infections / Q000209:etiology*; D005549:Foreign-Body Reaction / Q000209:etiology*; D006023:Glycoproteins / Q000096:biosynthesis; D006801:Humans; D009504:Neutrophils / Q000276:immunology; D011134:Polysaccharides / Q000096:biosynthesis; D019736:Prostheses and Implants / Q000009:adverse effects*
chemical_list: D006023:Glycoproteins; D011134:Polysaccharides