Psychopathology in fragile X syndrome.
The fragile X syndrome is the most common known familial form of mental retardation. Young males commonly demonstrate hyperactivity and a short attention span, as well as physical abnormalities, some of which may lead to a diagnosis of Pervasive Developmental Disorder. Heterozygous females frequently demonstrate both a range of involvement with learning disabilities in math, and social anxiety. The more classical physical and behavioral features of this syndrome are reviewed.
Hagerman
R J
RJ
Child Development Unit, Children's Hospital, Denver.
Sobesky
W E
WE
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005600:Fragile X Syndrome / Q000235:genetics / Q000523:psychology*; D006579:Heterozygote; D006801:Humans; D008607:Intellectual Disability / Q000523:psychology*; D007805:Language Development Disorders / Q000523:psychology*; D008297:Male; D019964:Mood Disorders / Q000523:psychology; D011599:Psychopathology; D012729:Sex Chromosome Aberrations / Q000523:psychology*