[The functional heterogeneity of circulating polymorphonuclear leukocytes in acute myocardial infarct].
Cytofluorometric analysis, using immune complexes, consisting of human IgG and fluorescein isothiocianate (FITC)-labelled monospecific rabbit antibodies to human IgG, as fluorescent markers for polymorphonuclear leukocytes (PML), and microscopic analysis of modified NST-test probes with NADH2 or NADFH2 were employed to investigate PML functional heterogeneity of healthy individuals and patients with acute myocardial infarction. It was shown, that circular PML make up heterogeneous cell population in the following parameters: Fc gamma-receptors expression, oxidative derivates generation and cell oxidases activity and the degree of heterogeneity may change during nonspecific inflammatory process, which accompanies acute myocardial infarction.
Kreĭnina
M V
MV
Klebanov
G I
GI
Kuznetsov
S V
SV
Vakoliuk
R M
RM
Vladimirov
Iu A
IuA
D005434:Flow Cytometry / Q000379:methods; D006801:Humans; D008213:Lymphocyte Activation / Q000502:physiology; D008856:Microscopy, Fluorescence / Q000379:methods; D009203:Myocardial Infarction / Q000097:blood*; D009504:Neutrophils / Q000502:physiology*; D009580:Nitroblue Tetrazolium; D011961:Receptors, Fc / Q000378:metabolism
D011961:Receptors, Fc; D009580:Nitroblue Tetrazolium
Funktsional'naia geterogennost' tsirkuliruiushchikh polimorfnoiadernykh leĭkotsitov pri ostrom infarkte miokarda.