title: Forced subarachnoid air in transsphenoidal excision of pituitary tumors (pumping technique)
abstract: Inversion and prolapse into the sella of the superior capsule and the diaphragma sellae is the only condition that warrants, at least macroscopically, radical removal of tumors with suprasellar extension operated on via the transsphenoidal route. If this does not occur spontaneously, air can be introduced into the subarachnoid space through a lumbar spinal catheter to produce forced dissection of the suprasellar cisterns and collapse of the tumor capsule ("pumping technique"). This method permits complete removal of the neoplastic tissue. In a series of 124 transsphenoidal operations for tumors with suprasellar extension, spontaneous descent of the capsule occurred in only 26 cases. Forced dissection using air distension of the cisterns was carried out in 88 cases, with complete success in 56 cases, partial success in 20, and no effect in 12. There were no complications or unwanted side effects in any patient.
authors.affiliation: Department of Functional Neurosurgery, 2nd Faculty of Medicine, University of Naples, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Spaziante
authors.forename: E
authors.initials: E
authors.lastname: de Divitiis
mesh_terms: D000388:Air; D005069:Evaluation Studies as Topic; D006801:Humans; D007267:Injections; D007432:Intraoperative Period; D009493:Neurosurgery / Q000379:methods*; D010911:Pituitary Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D011859:Radiography; D013100:Sphenoid Bone / Q000601:surgery; D013346:Subarachnoid Space