title: [Efficacy of a PVP-iodine compound on selected pathogens of the oral cavity in vitro].
abstract: The study was designed to test the efficacy of a PVP-iodine antiseptic agent on potentially pathogenic oral bacteria. A 0.5% concentration of the test compound was sufficient to inhibit the growth of 7 out of 8 tested strains. Only bacteroides gingivalis continued to grow during exposure to a 0.5 and 1% concentration of the test compound. Quantitative suspension experiments demonstrated that the onset of action occurred within five minutes. Quantitative suspension experiments with protein loading resulted in a lower efficacy of the tested agent. Results indicate that the tested compound may be recommended as an oral disinfectant.
authors.forename: R F
authors.initials: RF
authors.lastname: Müller
authors.forename: C
authors.initials: C
authors.lastname: Hopfner
authors.forename: D E
authors.initials: DE
authors.lastname: Lange
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D002710:Chlorhexidine / Q000494:pharmacology; D006801:Humans; D009055:Mouth / Q000382:microbiology; D011205:Povidone; D011206:Povidone-Iodine / Q000494:pharmacology*
chemical_list: D011206:Povidone-Iodine; D011205:Povidone; D002710:Chlorhexidine
vernacular_title: Wirksamkeit eines PVP-Jod-Präparates in vitro auf ausgewahlte Mundhöhlenkeime.