[Enzymo-immunoassay of progesterone receptors in human breast lesions and tumors. Comparison with a biochemical method].
The determination of progesterone receptors (RP) was performed on 80 benign and malignant human breast tumors with a single saturating dose method (10 nM) using dextran-coated charcoal (PR-Bio) and an enzymo-immunoassay (PgR-EIA). There was a significant correlation between the 2 methods qualitatively (P less than 0.001) and quantitatively (r = 0.79). However the results were significantly higher using the PgR-EIA method than the PR-Bio method (P = 0.04) with a regression line Y = 0.81 x +0.58.
Delarue
J C
JC
Département de biologie clinique, Institut Gustave-Roussy, France.
Bertin
F
F
May-Levin
F
F
Mouriesse
H
H
D000230:Adenocarcinoma / Q000032:analysis; D000232:Adenofibroma / Q000032:analysis; D001943:Breast Neoplasms / Q000032:analysis*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D011933:Reagent Kits, Diagnostic; D011980:Receptors, Progesterone / Q000032:analysis*
D011933:Reagent Kits, Diagnostic; D011980:Receptors, Progesterone
Enzymo-immunodosage des récepteurs à la progestérone dans les lésions et tumeurs mammaires humaines comparison à la méthode biochimique.