[Surveillance of Plasmodium falciparum drug sensitivity in Yaounde and its surroundings (Cameroon). In vivo and in vitro study].
Among 172 strains collected in Yaoundé 60% are chloroquine-resistant, 37% are amodiaquine-resistant, instead of quinine and mefloquine which are completely efficient. Among 30 strains collected at a rural health center (where self treatment decreases), 27% are chloroquine-resistant. New therapeutic schemes for first and second line treatment in endemic areas must be evaluated.
Hengy
C
C
Organisation de Coordination pour la Lutte contre les Endémies en Afrique Centrale (OCEAC), Yaoundé Cameroun.
Garrigue
G
G
Abissègue
B
B
Ghogomu
N A
NA
Gazin
P
P
Gelas
H
H
Kouka-Bemba
D
D
Le Bras
J
J
Jambou
R
R
D000293:Adolescent; D000328:Adult; D000655:Amodiaquine / Q000494:pharmacology; D000818:Animals; D000962:Antimalarials / Q000494:pharmacology / Q000627:therapeutic use*; D002163:Cameroon; D002648:Child; D002675:Child, Preschool; D002738:Chloroquine / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D007223:Infant; D008288:Malaria / Q000188:drug therapy*; D015767:Mefloquine; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010963:Plasmodium falciparum / Q000187:drug effects*; D011803:Quinine / Q000494:pharmacology; D011804:Quinolines / Q000494:pharmacology; D012424:Rural Population
D000962:Antimalarials; D011804:Quinolines; D000655:Amodiaquine; D002738:Chloroquine; D011803:Quinine; D015767:Mefloquine
Surveillance de la chimiosensibilité de Plasmodium falciparum à Yaoundé et ses environs (Cameroun). Etude in vivo, in vitro.