[The frequency of sister chromatid exchanges in cultured cells of mouse blood, bone marrow and spleen].
Analysis of factors leading to the increase of SCE in vitro is presented. Frequency of SCE is the same in the blood, spleen, marrow cell culture and does not influence upon the time of culture and BDU or BDC concentration. The authors consider that procedure preparation of the culture leads to an increase of SCE in vitro as compared to in vivo.
Chebotarev
A N
AN
Golovina
M E
ME
D000818:Animals; D001773:Blood Cells / Q000187:drug effects / Q000648:ultrastructure; D001853:Bone Marrow / Q000187:drug effects* / Q000648:ultrastructure; D001972:Bromodeoxycytidine / Q000494:pharmacology; D001973:Bromodeoxyuridine / Q000494:pharmacology; D002478:Cells, Cultured / Q000187:drug effects / Q000648:ultrastructure; D004305:Dose-Response Relationship, Drug; D051379:Mice; D012854:Sister Chromatid Exchange / Q000187:drug effects*; D013154:Spleen / Q000187:drug effects* / Q000648:ultrastructure; D013997:Time Factors
D001972:Bromodeoxycytidine; D001973:Bromodeoxyuridine
Chastota sestrinskikh khromatidnykh obmenov v kul'tiviruemykh kletkakh krovi, kostnogo mozga i selezenki mysheĭ.