title: Neuronal plasticity in the adult invertebrate nervous system.
abstract: This essay provides a brief overview of neuronal plasticity in adult invertebrate nervous systems. Our discussion focuses on the factors which influence sprouting by adult neurons, i.e., (1) the nature of the neuron itself, (2) axon integrity, (3) the presence of targets, (4) diffusible factors, and (5) ageing. Evidence that the neurites of some adult neurons exhibit a dynamic equilibrium of expansion and retraction is presented, a topic which prompted us to speculate on the significance of such plasticity in altered behavioral states. We conclude with some suggestions as to specific questions that need to be addressed by future studies in this challenging area.
authors.affiliation: Department of Medical Physiology, University of Calgary, Alberta, Canada.
authors.forename: A G
authors.initials: AG
authors.lastname: Bulloch
authors.forename: R L
authors.initials: RL
authors.lastname: Ridgway
mesh_terms: D000818:Animals; D006728:Hormones / Q000502:physiology; D007448:Invertebrates / Q000502:physiology*; D009473:Neuronal Plasticity / Q000187:drug effects
chemical_list: D006728:Hormones