[Antiperspirants and deodorants--ingredients and evaluation].
Antitranspirants and deodorants gain more and more interest. Aluminium chlorohydrate and aluminium zirkonium tetrachlorohydrate glycine complex are the most frequently used active ingredients in commercial antitranspirants today. Aluminium chloride and propantheline bromide, the anticholinergic substance, are important alternatives although less common. Active ingredients of deodorants are mainly perfumes or bactericidal/bacteriostatic substances, such as triclosan. In addition, there are substances which are meant to bind offending smells (e.g. zinc ricinoleate) or to influence the skin surface pH (e.g. triethyl citrate). As in the cosmetics industry in general, both safety and efficacy of a product are major parameters in the experimental and clinical evaluation. Establishment of efficacy is based on olfactory tests in model situations as well as on the detection of associated effects (e.g. influence on cutaneous microflora).
Lukacs
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VA
Dermatologischen Klinik und Poliklinik, Ludwig-Maximilians-Universität München.
Korting
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HC
D001252:Astringents / Q000032:analysis / Q000494:pharmacology*; D003836:Deodorants / Q000032:analysis / Q000494:pharmacology*; D006801:Humans; D013546:Sweating / Q000187:drug effects
D001252:Astringents; D003836:Deodorants
Antitranspirantien und Deodorantien--Wirkstoffe und Bewertung.