Thrombotic thrombocytopenic purpura.
Once formerly thought to be a rare disorder, thrombotic thrombocytopenic purpura (TTP) is becoming increasingly recognized. It is characterized by a pentad of clinical findings, including microangiopathic hemolytic anemia, thrombocytopenic purpura, neurologic and renal abnormalities, and fever. Following a case report, the major clinical findings, pathophysiologic findings, diagnoses, and use of various therapeutic modalities are discussed.
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D000328:Adult; D001241:Aspirin / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004176:Dipyridamole / Q000627:therapeutic use; D006801:Humans; D008297:Male; D010951:Plasma Exchange; D010956:Plasmapheresis; D011697:Purpura, Thrombotic Thrombocytopenic / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*
D004176:Dipyridamole; D001241:Aspirin