title: Serum magnesium and nerve conduction velocity in uraemic patients on chronic haemodialysis.
abstract: In 18 patients on regular haemodialysis treatment, the dialysate magnesium concentration (dMg) was lowered (from 0.5 to 0.25 mmol/litre) and the correlation between serum Mg level (sMg) and nerve conduction velocity was investigated before and one year after dMg variation, in order to ascertain whether hypermagnesaemia plays a role in the pathogenesis of peripheral neuropathy in patients on regular dialysis. The normalization of sMg (from 1.27 +/- SD 0.16 to 0.98 +/- 0.09 mmol/litre) did not result in any improvement in nerve conduction velocity, though such improvement has previously been reported; however, this discrepancy could be explained by the fact that sMg was not excessively high at the beginning of the study.
authors.affiliation: Servizio Recupero e Rieducazione Funzionale, Ente Ospedaliero, Casale Monferrato, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Cisari
authors.forename: P
authors.initials: P
authors.lastname: Gasco
authors.forename: G
authors.initials: G
authors.lastname: Calabrese
authors.forename: G
authors.initials: G
authors.lastname: Pratesi
authors.forename: M
authors.initials: M
authors.lastname: Gonella
mesh_terms: D000328:Adult; D015314:Dialysis Solutions / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008274:Magnesium / Q000008:administration & dosage / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009431:Neural Conduction / Q000187:drug effects*; D006435:Renal Dialysis; D014511:Uremia / Q000097:blood* / Q000503:physiopathology / Q000628:therapy
chemical_list: D015314:Dialysis Solutions; D008274:Magnesium