title: [Experience and results with a lactate dehydrogenase marker in vaginal secretions of women at high risk for endometrial cancer].
abstract: The authors present and discuss the results obtained with 202 Gynaegnost experiments in 161 women, between 45 and 65 years, nulliparous, or having experienced a late pregnancy, with menopause occurring after the age of 52 and undergoing or not estrogen-therapy after menopause, and presenting high blood pressure, obesity or diabetes. The purpose of this multicenter study, to be continued, was to demonstrate the efficacy of this tumor marker, in the early diagnosis of endometrial carcinoma, in high-risk women.
authors.affiliation: Clinique de Gynécologie à l'IPO, Porto.
authors.forename: M T
authors.initials: MT
authors.lastname: Osorio
authors.forename: R
authors.initials: R
authors.lastname: Morais
authors.forename: E
authors.initials: E
authors.lastname: Santos
authors.forename: D
authors.initials: D
authors.lastname: Silva
authors.forename: E
authors.initials: E
authors.lastname: Abraul
authors.forename: M M
authors.initials: MM
authors.lastname: Silva
authors.forename: A
authors.initials: A
authors.lastname: Azinhais
authors.forename: F
authors.initials: F
authors.lastname: Oliveira
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis*; D048909:Diabetes Complications; D004967:Estrogens / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000032:analysis*; D008593:Menopause; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D009765:Obesity / Q000150:complications; D012307:Risk Factors; D014594:Uterine Neoplasms / Q000201:enzymology*; D014621:Vagina / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor; D004967:Estrogens; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase
vernacular_title: Expérience et résultats obtenus avec un marqueur de déshydrogénase lactique dans la sécrétion vaginale chez des femmes à haut risque du carcinome de l'endomètre.