[Neurocysticercosis and praziquantel: long-term development in 100 patients].
Evaluation of results observed in a prospective study on the long term follow-up of 100 patients with neurocysticercosis (NC) is reported. Praziquantel (PZQ) was administered to the patients at their admission to the study. Follow-up time was over two years in 63 patients (maximum 118 months). Clinical conditions, TC findings and CSF changes were taken into account for the evaluation. Patients were evaluated periodically during the follow-up. Satisfactory results predominate (72.5%). Satisfactory results maintain a close relationship with clinical forms of the disease: good results predominate among those patients with clinical manifestations of NC which are not marked by intracranial hypertension of progressive character. Results of this long term follow-up evaluation favour the administration of PZQ to patients with NC.
Spina-França
A
A
Departamento de Neurologia, Faculdade de Medicina da Universidade de São Paulo, Brasil.
Nóbrega
J P
JP
Machado
L R
LR
Livramento
J A
JA
D000293:Adolescent; D000328:Adult; D000368:Aged; D001927:Brain Diseases / Q000134:cerebrospinal fluid / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D003551:Cysticercosis / Q000134:cerebrospinal fluid / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D004827:Epilepsy / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007427:Intracranial Pressure / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D011223:Praziquantel / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
D011223:Praziquantel
Neurocisticercose e praziquantel: evolução a longo prazo de 100 pacientes.