title: Escherichia coli serotype-39 capsular polysaccharide: primary structure and depolymerisation by a bacteriophage-associated glycanase.
abstract: The acidic capsular polysaccharide isolated from Escherichia coli O9:K39:H9 was investigated, using n.m.r. spectroscopy, methylation analysis, uronic acid degradation of the native and methylated polysaccharides, and bacteriophage-associated enzyme degradation. The structure of the repeating unit, which is shown below, is identical to that reported for Klebsiella serotype-61 capsular polysaccharide. (formula; see text)
authors.affiliation: School of Pharmaceutical Sciences, Rhodes University, Grahamstown, South Africa.
authors.forename: H
authors.initials: H
authors.lastname: Parolis
authors.forename: L A
authors.initials: LA
authors.lastname: Parolis
authors.forename: R D
authors.initials: RD
authors.lastname: Venter
mesh_terms: D000942:Antigens, Bacterial / Q000032:analysis*; D001435:Bacteriophages / Q000201:enzymology; D002240:Carbohydrate Sequence; D004926:Escherichia coli / Q000032:analysis* / Q000276:immunology; D006026:Glycoside Hydrolases / Q000494:pharmacology; D006868:Hydrolysis; D007709:Klebsiella / Q000032:analysis; D008070:Lipopolysaccharides / Q000032:analysis* / Q000276:immunology; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D014574:Uronic Acids / Q000494:pharmacology
chemical_list: D000942:Antigens, Bacterial; D008070:Lipopolysaccharides; D014574:Uronic Acids; D006026:Glycoside Hydrolases; C020668:glycanase