Studies of neutralizing properties of antacid preparations. Part 7. 27Al NMR studies of aluminum species formed during acid dissolution of some antacid preparations.
Neutralization of some aluminum containing antacid preparations with hydrochloric acid were studied by 27Al NMR spectroscopy. It has been found that the nature and composition of aluminum species produced during the acid dissolution of preparations depends upon the substance used and on the pH at which the neutralization reaction proceeds. The results are consistent with the presence of both monomeric and polymeric species in solution containing aluminum in octahedral and tetrahedral environments.
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Department of Inorganic and Analytical Chemistry, K. Marcinkowski Academy of Medicine, Poznań, Poland.
D000535:Aluminum / Q000032:analysis*; D000536:Aluminum Hydroxide / Q000032:analysis; D000863:Antacids / Q000032:analysis*; D055598:Chemical Phenomena; D002621:Chemistry; D005998:Glycine / Q000031:analogs & derivatives / Q000032:analysis; D006863:Hydrogen-Ion Concentration; D008276:Magnesium Hydroxide; D009682:Magnetic Resonance Spectroscopy; D012995:Solubility
D000863:Antacids; C010467:hydrotalcite; D000536:Aluminum Hydroxide; D000535:Aluminum; C007420:dihydroxyaluminum aminoacetate; D008276:Magnesium Hydroxide; D005998:Glycine