title: [Chlorhexidine in the treatment of root canal infection and its sequels].
abstract: The plaque inhibitor chlorhexidine digluconate was used for intra- and transcanal irrigation in the endodontic treatment triad for periapical lesions (circumscribed, diffuse, fistulating, cystic, suspected cystic lesions). 50 patients were followed up by clinical and standardized radiologic studies. In another 18 patients microbiologic criteria were also used. 16 root canals showed pretreatment infection with mixed aerobic and anaerobic organisms. Mechanical preparation of the root canals with or without extension of the foramen and triple irrigation with 0.5% chlorhexidine digluconate produced clinical relief of symptoms (49 pts.), sterility (14 of 18 pts.) and reduction of the size of periapical lesions (12 pts.). At a mean follow-up of 24 months 30 patients have so far shown complete restitution of periapical bone.
authors.forename: W
authors.initials: W
authors.lastname: Klimm
authors.forename: H
authors.initials: H
authors.lastname: Zeumer
authors.forename: H J
authors.initials: HJ
authors.lastname: Kloss
authors.forename: I
authors.initials: I
authors.lastname: Natusch
authors.forename: W
authors.initials: W
authors.lastname: Wildführ
mesh_terms: D000293:Adolescent; D000328:Adult; D002710:Chlorhexidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003788:Dental Pulp Diseases / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010483:Periapical Diseases / Q000188:drug therapy*; D011842:Radicular Cyst / Q000188:drug therapy*; D012388:Root Canal Irrigants / Q000627:therapeutic use*; D012390:Root Canal Therapy
chemical_list: D012388:Root Canal Irrigants; C010882:chlorhexidine gluconate; D002710:Chlorhexidine
vernacular_title: Chlorhexidin in der therapeutischen Trias des infizierten Wurzelkanals und seiner Folgeerkrankungen.