title: Hairy cell leukemia--mediastinal involvement. A report of two cases and review of the literature.
abstract: The clinical features of two patients with hairy cell leukemia involving the mediastinum are described. Both patients presented with acute chest pain 2-3 months prior to diagnosis being made. In one patient mediastinal disease was recorded only by computerized tomography of the thorax. There was good response of mediastinal disease to alpha-interferon in both patients, in spite of persisting bone marrow involvement with hairy cell leukemia.
authors.affiliation: ICRF Department of Medical Oncology, St Bartholomew's Hospital, London, U.K.
authors.forename: S T
authors.initials: ST
authors.lastname: Malik
authors.forename: J
authors.initials: J
authors.lastname: Amess
authors.forename: A J
authors.initials: AJ
authors.lastname: D'Ardenne
authors.forename: T A
authors.initials: TA
authors.lastname: Lister
mesh_terms: D000328:Adult; D001853:Bone Marrow / Q000473:pathology; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use; D007943:Leukemia, Hairy Cell / Q000473:pathology* / Q000628:therapy; D008297:Male; D008479:Mediastinal Neoplasms / Q000473:pathology* / Q000628:therapy; D008875:Middle Aged
chemical_list: D007370:Interferon Type I