Perfluoro-N-[4-(1H-tetrazol-5-ylmethyl)phenyl]alkanamides. A new class of oral antidiabetic agents.
Kees
K L
KL
Medicinal Chemistry Department, Wyeth-Ayerst Research, Princeton, New Jersey 08543-8000.
Cheeseman
R S
RS
Prozialeck
D H
DH
Steiner
K E
KE
D000284:Administration, Oral; D000813:Anilides / Q000138:chemical synthesis* / Q000494:pharmacology; D000818:Animals; D001786:Blood Glucose; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000494:pharmacology; D007004:Hypoglycemic Agents / Q000138:chemical synthesis*; D007328:Insulin / Q000097:blood; D051379:Mice; D008820:Mice, Obese; D013329:Structure-Activity Relationship
D000813:Anilides; D001786:Blood Glucose; D006845:Hydrocarbons, Fluorinated; D007004:Hypoglycemic Agents; D007328:Insulin