title: Metabolic acidosis with an elevated anion gap.
abstract: Determining the cause of metabolic acidosis with a high anion gap may present a diagnostic challenge. Possible causes include ketoacidosis, certain toxic ingestions, renal failure and lactic acidosis. Many of these entities present with nausea, vomiting and changes in mental status; however, there are specific hallmarks in the signs, symptoms and laboratory findings that help to differentiate among them.
authors.affiliation: Medical Center, Beaver, Pennsylvania.
authors.forename: J A
authors.initials: JA
authors.lastname: Hertford
authors.forename: J P
authors.initials: JP
authors.lastname: McKenna
authors.forename: B N
authors.initials: BN
authors.lastname: Chamovitz
mesh_terms: D000136:Acid-Base Equilibrium; D000138:Acidosis / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D058186:Acute Kidney Injury / Q000150:complications; D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D007662:Ketosis / Q000150:complications; D008297:Male; D011041:Poisoning / Q000150:complications