title: [Convergent origin of repeats in genes coding for globular proteins. An analysis of the factors determining the presence of inverted and symmetrical repeats].
abstract: The factors, determining the presence of inverted and symmetrical repeats in genes coding for globular proteins, have been analysed. An interesting property of genetical code has been revealed in the analysis of symmetrical repeats: the pairs of symmetrical codons corresponded to pairs of amino acids with mostly similar physical-chemical parameters. This property may explain the presence of symmetrical repeats and palindromes only in genes coding for beta-structural proteins-polypeptides, where amino acids with similar physical-chemical properties occupy symmetrical positions. A stochastic model of evolution of polynucleotide sequences has been used for analysis of inverted repeats. The modelling demonstrated that only limiting of sequences (uneven frequencies of used codons) is enough for arising of nonrandom inverted repeats in genes.
authors.forename: V V
authors.initials: VV
authors.lastname: Solov'ev
authors.forename: A E
authors.initials: AE
authors.lastname: Kel'
authors.forename: N A
authors.initials: NA
authors.lastname: Kolchanov
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics*; D001483:Base Sequence; D005075:Biological Evolution; D007446:Chromosome Inversion; D003062:Codon / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics; D005798:Genes, Bacterial; D005815:Genetic Code; D008957:Models, Genetic; D008969:Molecular Sequence Data; D012091:Repetitive Sequences, Nucleic Acid
chemical_list: D001426:Bacterial Proteins; D003062:Codon
vernacular_title: Konvergentnoe proiskhozhdenie povtorov v genakh, kodiruiushchikh globuliarnye belki. Analiz faktorov, obuslavlivaiushchikh nalichie invertirovannykh i simmetrichnykh povtorov.