Structures and functions associated with the group of mammalian lectins containing collagen-like sequences.
The number of proteins found in body fluids and at cell surfaces, which are known to display carbohydrate-binding properties, continues to increase rapidly. In these proteins, in addition to a domain associated with lectin properties, one or more, non-lectin domains are present. It is possible that binding of sugar residues by the lectin domain may be important in triggering a variety of recognition and clearance mechanisms via the non-lectin domains. The group of lectins containing collagen-like sequences may provide some insight into structure/function relationships of the different domains in view of the well defined structures already available for several of these molecules.
Thiel
S
S
Institut for Medicinsk Microbiologi, J.B. Winsløwsvej 19, Odense C. Denmark.
Reid
K B
KB
D000595:Amino Acid Sequence; D000818:Animals; D003094:Collagen / Q000235:genetics; D037102:Lectins / Q000235:genetics / Q000502:physiology*; D008322:Mammals; D008969:Molecular Sequence Data
D037102:Lectins; D003094:Collagen