title: Angioscope-assisted occlusion of venous tributaries with prolamine in in situ femoropopliteal bypass: preliminary results of canine experiments.
abstract: Ten mongrel dogs underwent left lower extremity in situ femoropopliteal bypass with femoral vein. A 20 to 25 cm myocutaneous bridge was left between femoral and popliteal anastomoses. A 2.8 mm angioscope was introduced intraluminally to visualize venous tributaries (VT). A balloon occlusion catheter was placed alongside the angioscope and directed in each VT. Prolamine was injected into each VT to effect occlusion. Seven dogs were followed up for 1 week and three dogs for 1 month. A total of 34 VT (range one to five per dog) were available for attempted occlusion. Twenty-nine of 84 (85%) VT were able to be occluded based on comparison of pre-VT and post-VT occlusion angiograms. Poor visualization of VT or VT too small to admit the 5F catheter were reasons for failure. We conclude that (1) in the canine model studied angioscope-assisted occlusion of femoropopliteal during bypass is technically feasible, (2) this technical detail makes unnecessary medial thigh dissection for exposure of the vein graft, and (3) during short-term observation prolamine appeared to be a suitable occluding substance.
authors.affiliation: Department of Surgery, Akron City Hospital, OH 44309.
authors.forename: J P
authors.initials: JP
authors.lastname: Pigott
authors.forename: D L
authors.initials: DL
authors.lastname: Donovan
authors.forename: J A
authors.initials: JA
authors.lastname: Fink
authors.forename: W V
authors.initials: WV
authors.lastname: Sharp
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D002404:Catheterization / Q000295:instrumentation; D004285:Dogs; D004621:Embolization, Therapeutic / Q000295:instrumentation* / Q000379:methods; D019723:Endoscopes; D005263:Femoral Artery / Q000601:surgery*; D005268:Femoral Vein / Q000637:transplantation; D005500:Follow-Up Studies; D005782:Gels / Q000627:therapeutic use; D007430:Intraoperative Care / Q000379:methods*; D011150:Popliteal Artery / Q000601:surgery*; D011506:Proteins / Q000627:therapeutic use*; D013536:Suture Techniques; D014014:Tissue Adhesives / Q000627:therapeutic use*
chemical_list: D005782:Gels; D011506:Proteins; D014014:Tissue Adhesives