[Are there correlations of hormonal activity in pheochromocytoma and serum as well as erythrocyte sodium and potassium concentrations in patients with pheochromocytoma].
Interrelationship between serum Na+, K+ concentrations and the excretion of norepinephrine (NA), epinephrine (A) in the urine was studied in 69 patients aged 15-69 with pheochromocytoma (PH), and between serum Na+, K+ concentrations and serum NA, A levels in 53 patients. Furthermore, in 15 patients correlation between Na+, K+ concentrations in erytrocytes and serum NA, A levels was estimated. Na+ and K+ concentrations were determined using photometric analysis, NA and A excretion in the urine using fluorometric method and in blood by radiometry. Hypokalemia and hyponatremia were stated in 22% and 19% of patients with PH, respectively. Only in patients with electrolytic disorders correlation of serum as well as erythrocyte Na+ concentrations with serum NA level and between serum K+ and A concentrations were proved. In the part of studied patients with PH, the NA and A excess induced disorders of electrolytic homeostasis.
Wocial
B
B
Januszewicz
W
W
Feltynowski
T
T
Drygieniec
D
D
D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000097:blood / Q000378:metabolism*; D000328:Adult; D000368:Aged; D004837:Epinephrine / Q000096:biosynthesis* / Q000502:physiology; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000378:metabolism* / Q000502:physiology; D010673:Pheochromocytoma / Q000097:blood / Q000378:metabolism*; D011188:Potassium / Q000097:blood*; D012964:Sodium / Q000097:blood*
D012964:Sodium; D011188:Potassium; D009638:Norepinephrine; D004837:Epinephrine
Czy istnieje współzaleźność miedzy czynnościa hormonalna guza chromochłonneego a steźeniem sodu i potasu we krwi i erytrocytach u chorych z pheochromocytoma?