[Determination of Shigella antigens in the feces of people, immunized with enteral vaccine prepared from S. flexneri antigen].
The dynamic determination of the presence of the specific antigen and its activity in the excreta of humans subjected to enteral immunization with vaccine prepared from S. flexneri antigen was made in the agglutination test and neutralization test with the use of, respectively, antibody and antigenic erythrocyte diagnosticums. In the feces and urine of the vaccinees antibodies occurred less commonly and, as a rule, they were less active than those detected in dysentery patients at the corresponding time from the beginning of the disease. The occurrence of Shigella antigens in the feces of the vaccinees was greater than in their urine at the corresponding time. Similarities and differences in the dynamics of the isolation of Shigella antigen from dysentery patients and from the vaccinees receiving enteral vaccine prepared from S. flexneri antigens were established.
Nurkina
N V
NV
Karal'nik
B V
BV
Borodaĭ
A P
AP
Vorontsov
N A
NA
Stoletov
V V
VV
D000293:Adolescent; D000942:Antigens, Bacterial / Q000032:analysis* / Q000652:urine; D004405:Dysentery, Bacillary / Q000175:diagnosis* / Q000517:prevention & control; D005243:Feces / Q000032:analysis; D006801:Humans; D008297:Male; D012763:Shigella flexneri / Q000276:immunology*; D014611:Vaccination
D000942:Antigens, Bacterial
Opredelenie antigena shigell v vydeleniiakh liudeĭ, privitykh énteralnoí dizenteriĭnoĭ vaktsinoĭ iz antigenov Shigella flexneri.