title: Effect of posture and physical activity on urinary protein excretion by patients with glomerular proteinuria diseases.
abstract: The rate of urinary protein excretion (Uprot.V) was evaluated in 20 patients with massive proteinuria caused by various histopathological types of glomerular disease. Measurements were made during five consecutive periods: period A (overnight bed rest) and periods B, C, D and E corresponding to normal everyday upright physical activity. Mean Uprot.V was significantly lower during period A (8.2 +/- 1.3 mg/min, mean +/- SEM) than during all the periods of physical activity (11.8 +/- 1.8 mg/min). For 5/20 patients, physical activity induced a mean percent increase of 340 +/- 200% and for 11 an increase of 51 +/- 7% was observed. Only in 4 patients was the rate of urinary protein excretion unaffected or decreased on the average by -20 +/- 9% during physical activity.
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, Brasil.
authors.forename: H M
authors.initials: HM
authors.lastname: Cruz
authors.forename: J
authors.initials: J
authors.lastname: Cruz
authors.forename: M C
authors.initials: MC
authors.lastname: Castro
authors.forename: M
authors.initials: M
authors.lastname: Marcondes
mesh_terms: D015444:Exercise; D005919:Glomerular Filtration Rate; D006801:Humans; D007674:Kidney Diseases / Q000652:urine*; D011187:Posture; D011507:Proteinuria / Q000652:urine*