The effect of oral nutritional supplements on head and neck cancer.
Fifty ambulatory patients with head and neck cancer treated by definitive radiation therapy at the Fox Chase Cancer Center were prospectively studied to determine the effect of oral nutritional supplements on both nutritional status and treatment response. Nutritional supplements maintained serum albumin during and post treatment. Nutritional supplements were shown to increase total protein and total calorie intake rather than displace these nutrients in usual food intake. Equal weight loss occurred in both the supplemented and non-supplemented groups during the observation period of 6 months, with the same or greater amount of weight loss registered 10 weeks after the start of treatment. Food supplements did not affect treatment response or complications, nor did they offer any survival advantage.
Arnold
C
C
Department of Surgery, Fox Chase Cancer Center, Philadelphia, PA 19111.
Richter
M P
MP
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002986:Clinical Trials as Topic; D004734:Energy Metabolism; D005260:Female; D005527:Food, Fortified; D006258:Head and Neck Neoplasms / Q000178:diet therapy / Q000378:metabolism / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011897:Random Allocation; D012709:Serum Albumin / Q000378:metabolism; D014168:Transferrin / Q000378:metabolism
D012709:Serum Albumin; D014168:Transferrin