title: Second-phase optokinetic after-nystagmus and vestibular compensation.
abstract: To evaluate the direction-specific effect of optokinetic storage function on balance compensation after unilateral labyrinthectomy, squirrel monkeys (n = 12) were exposed to a prolonged (30 min) daily optokinetic stimulus (horizontal, constant speed-90 degrees/sec) for 14 days; either in the ipsilateral direction to the slow phase of spontaneous nystagmus, or in the contralateral direction, or without any optokinetic stimulus. The effect of optokinetic stimulus in ipsilateral direction (slow phase of OKAN-II in the opposite direction) was significantly more (p less than 0.001) in the vestibulo-oculomotor balance (static) regainment than the other two groups, but this group showed the severest gait deviation in the vestibulospinal balance function (p less than 0.05).
authors.affiliation: Department of Otorhinolaryngology & Communicative Sciences, Baylor College of Medicine, Houston, Texas 77030-3498.
authors.forename: M
authors.initials: M
authors.lastname: Igarashi
authors.forename: M
authors.initials: M
authors.lastname: Ishii
authors.forename: S
authors.initials: S
authors.lastname: Chae
authors.forename: T
authors.initials: T
authors.lastname: Himi
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D007758:Ear, Inner / Q000503:physiopathology / Q000601:surgery; D005133:Eye Movements; D009759:Nystagmus, Pathologic / Q000503:physiopathology*; D009760:Nystagmus, Physiologic; D010775:Photic Stimulation; D004856:Postural Balance / Q000502:physiology; D012027:Reflex, Vestibulo-Ocular / Q000502:physiology*; D012453:Saimiri