[Oral anticoagulants and platelet anti-aggregants in the prevention of metastases: state of the art and perspectives of a combined therapy].
Metastases formation involves platelets activation and coagulation cascade. Drugs interfering with such mechanisms have shown promising activity in controlling neoplastic spread. Particularly, combined treatment with coumarins and the most recent antiplatelet agents could open interesting therapeutic perspectives.
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D000284:Administration, Oral; D004359:Drug Therapy, Combination; D006801:Humans; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000517:prevention & control*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D014859:Warfarin / Q000008:administration & dosage / Q000627:therapeutic use*
D010975:Platelet Aggregation Inhibitors; D014859:Warfarin
Anticoagulanti orali ed antiaggreganti piastrinici nella prevenzione delle metastasi: stato dell'arte e prospettive di una terapia combinata.