title: Transrectal fine-needle aspiration and truecut needle biopsy of the prostate: a blinded comparison of accuracy.
abstract: Transrectal needle aspiration biopsy and core biopsy of the prostate were performed simultaneously on 88 men with prostatic nodules. Cytologic and histologic assessments were made in a blinded, independent fashion, and the results were compared. All patients with positive findings on aspiration also had positive findings on core biopsy, for a positive predictive value for aspiration of 100%. However, five negative and six "insufficient" results obtained by aspiration were positive on core biopsy, for a negative predictive value for aspiration of 88%. This experience support the use of needle aspiration as an initial diagnostic maneuver in the assessment of prostatic nodules.
authors.affiliation: Department of Urology, Sunnybrook Medical Centre, University of Toronto, Ont.
authors.forename: L H
authors.initials: LH
authors.lastname: Klotz
authors.forename: P A
authors.initials: PA
authors.lastname: Shaw
authors.forename: J R
authors.initials: JR
authors.lastname: Srigley
mesh_terms: D001707:Biopsy, Needle / Q000379:methods*; D002277:Carcinoma / Q000473:pathology*; D002986:Clinical Trials as Topic; D005069:Evaluation Studies as Topic; D006801:Humans; D008297:Male; D011237:Predictive Value of Tests; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000473:pathology*