Precision and accuracy of absolute lymphocyte counts.
A critique of leukocyte counting using automated hematology instruments is presented. Important preanalytical variables include the anticoagulant and specimen assay delays. The precision of counts is directly related to the number of leukocytes counted. Criteria for the selection of an acceptable hematology laboratory for lymphocyte counts for CD4 determinations are presented.
Koepke
J A
JA
Department of Hospital Laboratories, Duke University Medical Center Durham, North Carolina 27710.
Landay
A L
AL
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology*; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis* / Q000276:immunology; D005434:Flow Cytometry / Q000592:standards; D006801:Humans; D007958:Leukocyte Count / Q000295:instrumentation / Q000592:standards*; D011786:Quality Control; D013601:T-Lymphocytes / Q000032:analysis / Q000276:immunology
D000945:Antigens, Differentiation, T-Lymphocyte