title: [Cardiospermum--a new phytogenic drug in dermatology?].
abstract: In a double blind study on persons with healthy skin, we tested the efficacy of cardiospermum ointment against the ointment base only. There were no significant differences between placebo and active substance regarding clinical evaluation, light reflection photometry, and transepidermal water loss. By means of doppler laser flowmetry, we found a decrease in corial blood supply after 16 hours' application of cardiospermum, which suggests a possible antiphlogistic effect.
authors.affiliation: Hautklinik des Städtischen Klinikums Karlsruhe.
authors.forename: W
authors.initials: W
authors.lastname: Gehring
authors.forename: M
authors.initials: M
authors.lastname: Gloor
mesh_terms: D000328:Adult; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D006801:Humans; D009824:Ointments; D010936:Plant Extracts / Q000494:pharmacology*; D011897:Random Allocation; D012039:Regional Blood Flow / Q000187:drug effects; D012867:Skin / Q000098:blood supply / Q000187:drug effects*; D014870:Water Loss, Insensible / Q000187:drug effects
chemical_list: D009824:Ointments; D010936:Plant Extracts
vernacular_title: Cardiospermum--ein neuer pflanzlicher Wirkstoff in der Dermatologie?