Prevention of oral mucositis in radiation therapy: a controlled study with benzydamine hydrochloride rinse.
Benzydamine hydrochloride rinse was shown to prevent oral mucositis in radiation therapy. Prevention of mucositis allows reduction in morbidity of one of the therapy limiting complications of radiotherapy for cancer therapy.
Epstein
J B
JB
Cancer Control Agency of British Columbia, Vancouver, Canada.
Stevenson-Moore
P
P
Jackson
S
S
Mohamed
J H
JH
Spinelli
J J
JJ
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D001591:Benzydamine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006258:Head and Neck Neoplasms / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa; D011446:Prospective Studies; D011720:Pyrazoles / Q000627:therapeutic use*; D011878:Radiotherapy / Q000009:adverse effects*; D013280:Stomatitis / Q000209:etiology / Q000517:prevention & control*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D011720:Pyrazoles; D001591:Benzydamine