title: Congenital chloride diarrhoea in Kuwaiti children.
abstract: Congenital chloride diarrhoea was diagnosed in 16 Kuwaiti children over a 7 year period (1980-1986) with an estimated incidence of 7.6 per 100,000 live births. The mean age at diagnosis was 3.2 months (range 1 week to 5 months). There were 9 boys and 7 girls with a mean age of 3 years 10 months (range 10 months to 7 years). All children had a shortened gestational period, abdominal distension and chronic diarrhoea. The serum electrolytes in all patients prior to treatment showed hyponatraemia, hypokalaemia, hypochloraemia and metabolic alkalosis. The diagnosis was confirmed by a stool chloride content that exceeded the sum of faecal sodium and potassium. Fifteen patients survived and showed catch-up growth with adequate replacement therapy and 1 died with renal failure.
authors.affiliation: Department of Paediatrics, Farwania Hospital, Kuwait.
authors.forename: M M
authors.initials: MM
authors.lastname: Lubani
authors.forename: K I
authors.initials: KI
authors.lastname: Doudin
authors.forename: D C
authors.initials: DC
authors.lastname: Sharda
authors.forename: A A
authors.initials: AA
authors.lastname: Shaltout
authors.forename: T S
authors.initials: TS
authors.lastname: al-Shab
authors.forename: Y K
authors.initials: YK
authors.lastname: Abdul Al
authors.forename: M A
authors.initials: MA
authors.lastname: Said
authors.forename: M M
authors.initials: MM
authors.lastname: Salhi
authors.forename: S A
authors.initials: SA
authors.lastname: Ahmed
mesh_terms: D000450:Aldosterone / Q000097:blood; D000804:Angiotensin II / Q000097:blood; D002648:Child; D002675:Child, Preschool; D002712:Chlorides / Q000097:blood*; D003906:Developing Countries; D003937:Diagnosis, Differential; D003968:Diarrhea, Infantile / Q000097:blood*; D005243:Feces / Q000032:analysis*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000097:blood*; D008297:Male; D012083:Renin / Q000097:blood
chemical_list: D002712:Chlorides; D000804:Angiotensin II; D000450:Aldosterone; D012083:Renin