title: A community outbreak of group A beta haemolytic streptococci with transferable resistance to erythromycin.
abstract: Erythromycin resistance amongst group A streptococci (GAS) in Great Britain is a relatively rare occurrence and outbreaks have been sporadically reported. Over an 8-month period in 1986 ten associated cases occurred in the town of Bridgewater in Somerset. Isolates were group A, type M4 and resistant to erythromycin (MIC 8 mg/l) but sensitive to lincomycin and clindamycin. Erythromycin resistance was transferable from all isolates to a group A recipient strain. No plasmid DNA could be detected in the original isolates or transconjugants.
authors.affiliation: Public Health Laboratory, Musgrove Park Hospital, Taunton, Somerset.
authors.forename: R J
authors.initials: RJ
authors.lastname: Scott
authors.forename: J
authors.initials: J
authors.lastname: Naidoo
authors.forename: N F
authors.initials: NF
authors.lastname: Lightfoot
authors.forename: R C
authors.initials: RC
authors.lastname: George
mesh_terms: D000328:Adult; D002648:Child; D002675:Child, Preschool; D003227:Conjugation, Genetic; D004196:Disease Outbreaks; D004352:Drug Resistance, Microbial / Q000235:genetics; D004739:England; D004917:Erythromycin / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012574:Schools; D013290:Streptococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000235:genetics / Q000302:isolation & purification
chemical_list: D004917:Erythromycin