Spinal abnormalities in camptomelic dysplasia.
Significant spinal abnormalities were found in eight patients (average age of 6 years, 5 months) with camptomelic dysplasia. The late ossification of the midthoracic pedicles served as a clear diagnostic criterion for the syndrome. Scoliosis averaging 63 degrees was found in all seven nonquadriplegic cases. Thoracic hyperkyphosis averaging 126 degrees was seen in six (75%) of the patients, while cervical kyphosis averaging 66 degrees was noted in three (38%). Vertebral body hypoplasia appeared to be a major cause of deformity. This study clarifies that patients with camptomelic dysplasia are surviving longer than previously expected and therefore should have their spinal deformities treated aggressively.
Coscia
M F
MF
Department of Orthopaedic Surgery, Indiana University Medical Center, Indianapolis.
Bassett
G S
GS
Bowen
J R
JR
Ogilvie
J W
JW
Winter
R B
RB
Simonton
S C
SC
D000293:Adolescent; D000328:Adult; D001848:Bone Diseases, Developmental / Q000150:complications* / Q000000981:diagnostic imaging; D002356:Cartilage / Q000648:ultrastructure; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007738:Kyphosis / Q000601:surgery; D011782:Quadriplegia / Q000209:etiology; D011859:Radiography; D013122:Spinal Diseases / Q000209:etiology* / Q000601:surgery; D013131:Spine / Q000002:abnormalities* / Q000601:surgery