Epidural diamorphine and bupivacaine in labour.
A double-blind randomised study was performed to assess the analgesic effect of epidural diamorphine, administered with bupivacaine, on primigravid women in labour. Fifty patients received 0.25% bupivacaine 10 ml via the epidural catheter as their initial dose; patients in Group 1 received diamorphine 5 mg with the bupivacaine. A 0.1% bupivacaine infusion was started at 10 minutes and bolus doses of bupivacaine were given if required. There was a significant reduction in rate of bupivacaine administration, pain scores at 20 and 30 minutes, number of supplements required, and degree of motor blockade in the diamorphine group.
McGrady
E M
EM
Department of Anaesthetics, Southern General Hospital, Glasgow.
Brownhill
D K
DK
Davis
A G
AG
D015360:Analgesia, Epidural; D000773:Anesthesia, Obstetrical; D002045:Bupivacaine / Q000008:administration & dosage / Q000009:adverse effects; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D003932:Heroin / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D007743:Labor, Obstetric; D011247:Pregnancy; D011897:Random Allocation
D003932:Heroin; D002045:Bupivacaine