title: [Treatment of Parkinson tremor by chronic stimulation of the ventral intermediate nucleus of the thalamus].
abstract: Stereotactic ventral intermediate nucleus (Vim) thalamotomy may improve drug resistant severe parkinsonian tremor. However, tremor may recur and bilateral thalamotomy is known to induce unacceptable side effects in a proportion of patients. A high frequency (130 Hz) chronic Vim stimulation was performed in 4 parkinsonian patients, 2 of them having previously undergone a thalamotomy on the other side. Tremor was suppressed in all patients at the price of slight paresthesias. This improvement has been lasting from 2 to 14 months. Beneficial and adverse effects were suppressed at once each time the stimulation was stopped. These preliminary results are encouraging but a longer delay and more patients are obviously needed.
authors.affiliation: Service de Neurochirurgie, Hôpital A. Michallon, CHRU de Grenoble.
authors.forename: A L
authors.initials: AL
authors.lastname: Benabid
authors.forename: P
authors.initials: P
authors.lastname: Pollak
authors.forename: M
authors.initials: M
authors.lastname: Hommel
authors.forename: J M
authors.initials: JM
authors.lastname: Gaio
authors.forename: J
authors.initials: J
authors.lastname: de Rougemont
authors.forename: J
authors.initials: J
authors.lastname: Perret
mesh_terms: D000328:Adult; D000368:Aged; D004599:Electric Stimulation Therapy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000628:therapy*; D013238:Stereotaxic Techniques; D013787:Thalamic Nuclei; D013788:Thalamus / Q000601:surgery; D014202:Tremor / Q000209:etiology / Q000628:therapy*
vernacular_title: Traitement du tremblement parkinsonien par stimulation chronique du noyau ventral intermédaire du thalamus.