[Dynamic assessment of hemostasis after gynecological operations. I. Effect of gynecological operations on hemostatic function].
In 50 patients operated on from various gynaecological indications the haemostasis system was monitored determining its parameters before and 2 hours after the operation and again after 5 days. Besides routine tests of platelet-related haemostasis, clotting system and fibrinolysis the fibrinolytic activity was assessed in dynamic tests after venous stasis. The obtained results confirmed the presence of a tendency for development of the disseminated intravascular clotting syndrome with associated fibrinolysis activation immediately after the operation. On the fifth day a tendency was noted for thromboembolic complications which was prevented by increased synthesis of plasminogen activator in the vascular wall. The study confirmed the usefulness of prophylactic doses of heparin in patients with presence of risk factors. In the light of own investigations and a survey of the pertinent literature the authors suggest that simultaneous administration of small subcutaneous doses of heparin and application of intermittent compression would be the most adequate method of thrombosis prevention after operations in the small pelvis.
Soszka
T
T
Piszka
J
J
Falkowska
K
K
Falkowski
B
B
Lukasiak
T
T
D000328:Adult; D005260:Female; D005831:Genital Diseases, Female / Q000601:surgery*; D006487:Hemostasis / Q000502:physiology; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D008991:Monitoring, Physiologic; D011183:Postoperative Complications / Q000097:blood* / Q000517:prevention & control; D013923:Thromboembolism / Q000209:etiology* / Q000517:prevention & control
D006493:Heparin
Dynamiczna ocena hemostazy po operacjach ginekologicznych. I. Wpływ operacji ginekologicznych na zachowanie sie układu hemostazy.