Edema disease-like brain lesions in gnotobiotic piglets infected with Escherichia coli serotype O157:H7.
Gnotobiotic piglets inoculated with Escherichia coli serotype O157:H7 strains that produced Shiga-like toxin II developed brain lesions similar to those observed in edema disease of swine, including arteriolar necrosis and malacia. Loss of ability to produce Shiga-like toxin II resulted in loss of ability to cause brain lesions.
Francis
D H
DH
Department of Veterinary Science, South Dakota State University, Brookings 57007-1396.
Moxley
R A
RA
Andraos
C Y
CY
D000818:Animals; D001929:Brain Edema / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D004488:Edema Disease of Swine / Q000382:microbiology / Q000473:pathology*; D004926:Escherichia coli / Q000145:classification / Q000472:pathogenicity; D004927:Escherichia coli Infections / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D005856:Germ-Free Life; D013552:Swine; D014774:Virulence