title: Effect of sucrose-containing snacks on blood glucose control.
abstract: To determine whether ingestion of sucrose-containing snacks would affect blood glucose (BG) control, 16 subjects with insulin-dependent diabetes mellitus participated in a 5-day double-blind study at a diabetes camp. Eight subjects in the sucrose group ate sucrose-sweetened snacks twice a day, and 8 subjects in the control group ingested snacks that were sweetened with aspartame. The percentage of total daily calories derived from added sucrose was 7% for the sucrose group and 1% for the control group. Metabolic control was assessed by daily capillary BG measurements obtained before meals and the bedtime snack and by determination of serum fructosamine (F) concentrations on arrival at camp (day 0) and after 5 days on the study protocol (day 5). No significant difference was seen between the groups on day 0 (sucrose group [mean +/- SD]: BG 9.9 +/- 3.6 mM, F 3.54 +/- 0.38 mM; control group: BG 9.1 +/- 2.8 mM, F 3.74 +/- 0.71 mM) or day 5 (sucrose group: BG 8.8 +/- 2.6 mM, F 2.94 +/- 0.32 mM; control group: BG 7.4 +/- 2.8 mM, F 2.92 +/- 0.59 mM). We conclude that ingestion of sucrose, added to snacks in an amount up to 7% of total energy intake, does not adversely affect short-term BG control.
authors.affiliation: Department of Pediatrics, University of Illinois, College of Medicine, Peoria.
authors.forename: J E
authors.initials: JE
authors.lastname: Wise
authors.forename: K S
authors.initials: KS
authors.lastname: Keim
authors.forename: J L
authors.initials: JL
authors.lastname: Huisinga
authors.forename: P A
authors.initials: PA
authors.lastname: Willmann
mesh_terms: D000328:Adult; D001218:Aspartame; D001786:Blood Glucose / Q000378:metabolism*; D002986:Clinical Trials as Topic; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D004040:Dietary Carbohydrates / Q000494:pharmacology*; D004311:Double-Blind Method; D005260:Female; D019270:Fructosamine; D006595:Hexosamines / Q000097:blood; D006801:Humans; D008297:Male; D013395:Sucrose / Q000494:pharmacology*
chemical_list: D001786:Blood Glucose; D004040:Dietary Carbohydrates; D006595:Hexosamines; D019270:Fructosamine; D013395:Sucrose; D001218:Aspartame