[Adhesive cutaneous pharmaceutical forms].
The adhesive cutaneous pharmaceutical forms aimed to local action release the drug substance in view of a dermatological, traumatological, antirheumatic, cosmetic action. Two such preparations were obtained and their stability, consistency and pH were determined. The "in vitro" tests of their bioavailability revealed the dynamics of calcium ions release according to the associations of each preparation. The bioavailability determined by evaluating the pharmacological response demonstrated the antiinflammatory action obtained by the association of calcium ions with the components extracted from poplar muds. The therapeutical efficiency of the studied preparations has proved in the treatment of some sport injuries.
Gafiţanu
E
E
Matei
I
I
Mungiu
O C
OC
Pavelescu
M
M
Mîndreci
I
I
Apostol
I
I
Ionescu
G
G
D000269:Adhesives; D000279:Administration, Cutaneous; D000287:Administration, Topical; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage* / Q000493:pharmacokinetics; D001265:Athletic Injuries / Q000188:drug therapy; D001682:Biological Availability; D002626:Chemistry, Pharmaceutical; D004353:Drug Evaluation, Preclinical; D005260:Female; D006801:Humans; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D000269:Adhesives; D000893:Anti-Inflammatory Agents
Studiul unor forme farmaceutice adezive cutanate.