title: Nonpalpable breast tumors: diagnosis with stereotaxic localization and fine-needle aspiration.
abstract: Modern mammography is the most effective means of detecting nonpalpable breast cancers, but correct diagnosis for malignancy is made in only 20%-30% of the cases. The conventional method of lesion localization usually results in approximate placement of the hookwire in the breast. The authors report the results of stereotaxic localization, combined with fine-needle aspiration and cytologic study, performed in 528 cases. Clinically occult breast lesions were localized precisely (within 2 mm 96% of the time), sampled by means of a 23-gauge needle, and marked with either methylene blue or a hookwire for subsequent open excisional biopsy. The results indicate a sensitivity of 95%, specificity of 91%, and accuracy of 92% for the fine-needle aspiration procedure. This technique offers a significantly improved preoperative method of diagnosing small breast lesions with minimal pain, no complications, reduced cost, and no disfigurement or scar interfering with subsequent mammographic follow-up.
authors.affiliation: Department of General Surgery, Rush-Presbyterian-St Luke's Medical Center, Chicago, IL 60612.
authors.forename: K
authors.initials: K
authors.lastname: Dowlatshahi
authors.forename: H J
authors.initials: HJ
authors.lastname: Gent
authors.forename: R
authors.initials: R
authors.lastname: Schmidt
authors.forename: P M
authors.initials: PM
authors.lastname: Jokich
authors.forename: M
authors.initials: M
authors.lastname: Bibbo
authors.forename: E
authors.initials: E
authors.lastname: Sprenger
mesh_terms: D001707:Biopsy, Needle / Q000191:economics / Q000379:methods*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D008327:Mammography; D010173:Palpation; D011829:Radiation Dosage; D013238:Stereotaxic Techniques / Q000295:instrumentation