title: Metastatic brain tumours in Northern Ireland: a retrospective review in a closed community with emphasis on short term quality of life.
abstract: One hundred and nineteen consecutive patients with metastatic brain tumours who presented to the Provincial Neurosurgical Service in Northern Ireland were studied. The detection rate doubled after computerised tomography became available though the population in Northern Ireland over the years of study stayed relatively stable. Multiple tumours accounted for 38% while solitary tumours occurred mainly in the cerebellum or parietal lobe. Whereas 70% of patients presented with features of increased intracranial pressure and or lateralizing neurological signs, 20% had only vague symptoms. The primary site was lungs in a third of cases but in 33 cases (27.5%), the site of origin remained unknown. 42% of those 76 cases operated were adenocarcinoma. More than 80% of these patients in whom excision of the tumours were done, had a better quality of life at one month compared with improvement in only a third after biopsy.
authors.forename: C P
authors.initials: CP
authors.lastname: Chee
authors.forename: J A
authors.initials: JA
authors.lastname: Sharkey
authors.forename: R A
authors.initials: RA
authors.lastname: Cooke
authors.forename: D P
authors.initials: DP
authors.lastname: Byrnes
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D000368:Aged; D001932:Brain Neoplasms / Q000473:pathology / Q000556:secondary*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology; D008875:Middle Aged; D009660:Northern Ireland; D011788:Quality of Life; D012189:Retrospective Studies; D013997:Time Factors