[Activation of human natural killer cells by receptor-bound immunoglobulin G].
Fc receptor-bound human immunoglobulin G can be detected in vitro and in vivo on CD16+ natural killer cells. Cross-linking of CD16-bound IgG via monoclonal antibody results in increased cytotoxic activity of effector cells.
Schubert
J
J
Zentrum Innere Medizin und Dermatologie, Medizinischen Hochschule, Hannover.
Kolanus
W
W
Delany
P
P
Schmidt
R E
RE
D000911:Antibodies, Monoclonal / Q000276:immunology; D003602:Cytotoxicity, Immunologic; D005455:Fluorescent Antibody Technique; D006801:Humans; D006825:Hybridomas; D007074:Immunoglobulin G / Q000276:immunology* / Q000378:metabolism; D007694:Killer Cells, Natural / Q000276:immunology*; D008213:Lymphocyte Activation; D011961:Receptors, Fc / Q000276:immunology* / Q000378:metabolism
D000911:Antibodies, Monoclonal; D007074:Immunoglobulin G; D011961:Receptors, Fc
Aktivierung humaner natürlicher Killer-Zellen über rezeptorgebundenes Immunglobulin G.