Correlation between total and free magnesium levels in human red blood cells. Influence of HLA antigens.
Total and free magnesium contents were determined by atomic absorption spectrophotometry and 31P nuclear magnetic resonance on red blood cells of healthy blood donors of known HLA groups. A statistically significant correlation was found between free and total magnesium contents (r = 0.67, P less than 0.02). The previously described low total magnesium contents in HLA-B35+ subjects were associated with low free Mg2+ contents. Therefore, total and free magnesium and HLA-associated genetic factors are closely related.
Santarromana
M
M
CNRS, Faculté de Pharmacie, Paris, France.
Delepierre
M
M
Féray
J C
JC
Franck
G
G
Garay
R
R
Henrotte
J G
JG
D004912:Erythrocytes / Q000378:metabolism*; D006680:HLA Antigens / Q000276:immunology*; D006801:Humans; D008274:Magnesium / Q000097:blood*; D009682:Magnetic Resonance Spectroscopy; D008297:Male
D006680:HLA Antigens; D008274:Magnesium