title: Human type II collagen gene (COL2A1) assigned to chromosome 12q13.1-q13.2 by in situ hybridization with biotinylated DNA probe.
abstract: We have made a regional assignment of the type II collagen gene (COL2A1) on human chromosome 12 by means of an in situ hybridization technique with a biotinylated DNA probe. The precise localization of the signal was mapped to the band 12q13.1-q13.2. This result was in agreement with the previous mapping by isotopic in situ hybridization technique (12q13.1-q13.2), but not with the result of Southern hybridization analysis using somatic cell hybrids (12q14.3).
authors.forename: E
authors.initials: E
authors.lastname: Takahashi
authors.forename: T
authors.initials: T
authors.lastname: Hori
authors.forename: J B
authors.initials: JB
authors.lastname: Lawrence
authors.forename: J
authors.initials: J
authors.lastname: McNeil
authors.forename: R H
authors.initials: RH
authors.lastname: Singer
authors.forename: P
authors.initials: P
authors.lastname: O'Connell
authors.forename: M
authors.initials: M
authors.lastname: Leppert
authors.forename: R
authors.initials: R
authors.lastname: White
mesh_terms: D002871:Chromosome Banding; D002874:Chromosome Mapping; D002881:Chromosomes, Human, Pair 12; D003094:Collagen / Q000235:genetics*; D015342:DNA Probes; D006801:Humans; D009693:Nucleic Acid Hybridization
chemical_list: D015342:DNA Probes; D003094:Collagen