[Biocompatibility in long-term hemodialysis: facts--theories--clinical significance].
Biocompatible hemodialysis membranes do not cause major untoward effects due to blood-interface reactions. In principle, however, every component of the extracorporeal circuit may have detrimental effects. Biocompatibility parameters include for example complement components, leukocyte drop, elastase release and interleukin-1 generation. Furthermore, ethylene oxide sensitization, beta 2-microglobulin clearance and endotoxin contamination are of importance. The clinical relevance of biocompatibility in modern hemodialysis is critically discussed.
Bosch
T H
TH
Medizinische Klinik I, Klinikums Grosshadern, Ludwig-Maximilians-Universität, München.
Blumenstein
M
M
Gurland
H J
HJ
D001672:Biocompatible Materials; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D007688:Kidneys, Artificial; D008567:Membranes, Artificial; D012307:Risk Factors
D001672:Biocompatible Materials; D008567:Membranes, Artificial
Biokompatibilität bei Langzeithämodialyse: Fakten--Theorien--Klinische Bedeutung.