title: Adenocarcinoma of the uterine cervix: prognostic factors and patterns of recurrence.
abstract: Survival data, prognostic factors, and patterns of recurrence were analyzed for 70 women with adenocarcinoma of the uterine cervix treated between 1968 and 1982. The 5-year survival rates for stages I, II, and III-IV were 82, 90, and 38%, respectively. Control of pelvic tumor was achieved in 82, 80, and 12.5% of cases of stage I, II, and III-IV disease, respectively. When radiation therapy techniques alone were employed, pelvic control was achieved in 100% of stage I and 75% of stage II cases. Tumor grade was an important prognostic factor in stage I disease, with 92% of patients with grade 1 and 2 lesions surviving 5 years, in contrast to 68% of patients with grade 3 lesions (P less than 0.05, log rank test).
authors.affiliation: Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, Massachusetts 02115.
authors.forename: H M
authors.initials: HM
authors.lastname: Goodman
authors.forename: C A
authors.initials: CA
authors.lastname: Buttlar
authors.forename: J M
authors.initials: JM
authors.lastname: Niloff
authors.forename: W R
authors.initials: WR
authors.lastname: Welch
authors.forename: A
authors.initials: A
authors.lastname: Marck
authors.forename: E J
authors.initials: EJ
authors.lastname: Feuer
authors.forename: E A
authors.initials: EA
authors.lastname: Lahman
authors.forename: E L
authors.initials: EL
authors.lastname: Jenison
authors.forename: R C
authors.initials: RC
authors.lastname: Knapp
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology* / Q000628:therapy; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D011379:Prognosis; D002583:Uterine Cervical Neoplasms / Q000401:mortality / Q000473:pathology* / Q000628:therapy