title: Uptake and acylation of 2-acyl-lysophospholipids by Escherichia coli.
abstract: The efficiency of extracellular 2-acyl-lysophospholipid incorporation into Escherichia coli membranes and the acyl donor utilized to acylate the 2-acyl-lysophospholipid was determined. Exogenous 2-acyl-lysophospholipids were acylated via the acyl-acyl carrier protein synthetase/2-acylglycerophosphoethanolamine acyltransferase pathway. The maximum extent of 2-acyl-lysophospholipid incorporation into the membrane was approximately 2.5% of the normal phospholipid biosynthetic rate.
authors.affiliation: Department of Biochemistry, St. Jude Children's Research Hospital, Memphis, Tennessee 38101.
authors.forename: L
authors.initials: L
authors.lastname: Hsu
authors.forename: S
authors.initials: S
authors.lastname: Jackowski
authors.forename: C O
authors.initials: CO
authors.lastname: Rock
mesh_terms: D000215:Acylation; D001692:Biological Transport; D004926:Escherichia coli / Q000378:metabolism*; D008246:Lysophospholipids / Q000378:metabolism*; D019308:Palmitic Acid; D010169:Palmitic Acids / Q000378:metabolism; D013045:Species Specificity
chemical_list: D008246:Lysophospholipids; D010169:Palmitic Acids; D019308:Palmitic Acid