Cyclosporin associated demyelination following allogeneic bone marrow transplantation.
Neurological complications associated with cyclosporin administration are well documented. However their histopathological basis are ill-understood. We describe below a case of demyelination following cyclosporin administration to a patient following allogeneic bone marrow transplantation.
Lind
M J
MJ
CRC Department of Medical Oncology, Christie Hospital and Holt Radium Institute, Manchester, U.K.
McWilliam
L
L
Jip
J
J
Scarffe
J H
JH
Morgenstern
G R
GR
Chang
J
J
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016026:Bone Marrow Transplantation; D003131:Combined Modality Therapy; D003524:Cyclosporins / Q000009:adverse effects* / Q000627:therapeutic use; D003711:Demyelinating Diseases / Q000139:chemically induced*; D005260:Female; D006086:Graft vs Host Disease / Q000188:drug therapy; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000188:drug therapy / Q000628:therapy; D011183:Postoperative Complications / Q000209:etiology*
D003524:Cyclosporins