[Association of HLA with sarcoidosis].
HLA typing for the A, B, C, and DR loci with 38 antigens was performed in 12 patients with sarcoidosis. It showed that an increase in frequencies of HLA-BW22, DR3 and DRw8 was significantly correlated with sarcoidosis (P less than 0.05). The results were similar to those in Japanese patients, and were quite different from those in the white as well as in the black and probably suggested that it varied with Asian population. No association between HLA and clinical symptoms, clinical signs, and laboratory tests was found in our patients, which was consistent with the views reported in recent literature.
Wang
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D000328:Adult; D044466:Asian People; D002681:China; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D015235:HLA-B Antigens / Q000032:analysis; D015803:HLA-DR3 Antigen / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D012507:Sarcoidosis / Q000208:ethnology / Q000235:genetics / Q000276:immunology*
D006680:HLA Antigens; D015235:HLA-B Antigens; C105903:HLA-B22 antigen; D015803:HLA-DR3 Antigen