Electrophysiological evidence for an L-shaped interhemispheric connection in the cat.
Transcallosal potentials evoked by electrical stimulation with rectangular pulses of 1 ms, 5 c/s and variable intensity were recorded from the cortical surface in cats anesthetized with ketamine hydrochloride. Sites of stimulation and recording were selected by means of a cartesian map of most of the neocortex. In addition to the well known transcallosal projection pattern it was found that stimulation of a restricted posterior area evokes low voltage potentials over the contralateral symmetric area while high voltage potentials are recorded from a few sites located at the ipsilateral anterior cortex and from the area symmetric as to the latter. This L-shaped transcallosal connection may be involved in complex cortical processes and is compatible with effective results of partial anterior callosotomies in patients with multifocal epilepsy and frontal bisynchronism.
Cukiert
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Laboratory of Functional Neurosurgery, School of Medicine, University of São Paulo, Brazil.
Timo-Iaria
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C
D000818:Animals; D001931:Brain Mapping; D002415:Cats; D003337:Corpus Callosum / Q000033:anatomy & histology / Q000502:physiology*; D004558:Electric Stimulation; D004594:Electrophysiology; D005071:Evoked Potentials / Q000502:physiology*; D005260:Female; D008297:Male