title: [Enzymo-immunoassay of progesterone receptors in human breast lesions and tumors. Comparison with a biochemical method].
abstract: The determination of progesterone receptors (RP) was performed on 80 benign and malignant human breast tumors with a single saturating dose method (10 nM) using dextran-coated charcoal (PR-Bio) and an enzymo-immunoassay (PgR-EIA). There was a significant correlation between the 2 methods qualitatively (P less than 0.001) and quantitatively (r = 0.79). However the results were significantly higher using the PgR-EIA method than the PR-Bio method (P = 0.04) with a regression line Y = 0.81 x +0.58.
authors.affiliation: Département de biologie clinique, Institut Gustave-Roussy, France.
authors.forename: J C
authors.initials: JC
authors.lastname: Delarue
authors.forename: F
authors.initials: F
authors.lastname: Bertin
authors.forename: F
authors.initials: F
authors.lastname: May-Levin
authors.forename: H
authors.initials: H
authors.lastname: Mouriesse
mesh_terms: D000230:Adenocarcinoma / Q000032:analysis; D000232:Adenofibroma / Q000032:analysis; D001943:Breast Neoplasms / Q000032:analysis*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D011933:Reagent Kits, Diagnostic; D011980:Receptors, Progesterone / Q000032:analysis*
chemical_list: D011933:Reagent Kits, Diagnostic; D011980:Receptors, Progesterone
vernacular_title: Enzymo-immunodosage des récepteurs à la progestérone dans les lésions et tumeurs mammaires humaines comparison à la méthode biochimique.