title: The purine path to chemotherapy.
abstract: Research on antimetabolites of nucleic acid purines led to drugs for the treatment of acute leukemia (6-mercaptopurine and thioguanine), gout and hyperuricemia (allopurinol), and herpesvirus infections (acyclovir), and for the prevention of organ transplant rejection (azathioprine).
authors.affiliation: Wellcome Research Laboratories, Burroughs Wellcome Company, Research Triangle Park, NC 27709.
authors.forename: G B
authors.initials: GB
authors.lastname: Elion
mesh_terms: D000818:Animals; D004358:Drug Therapy; D006801:Humans; D011687:Purines
chemical_list: D011687:Purines