[Content of vasopressin and beta2-microglobulin in the blood in patients with diabetes mellitus type II accompanied by microangiopathy].
Altogether 50 patients with diabetes mellitus, type II, with the presence of microangiopathies and 10 healthy controls were investigated to study the pathogenesis of vascular complications. An increased level of vasopressin and a normal level of beta 2-microglobulin were radioassayed in the blood plasma of the examinees. An acute furosemide test made it possible to establish 3 types of responses of vasopressin secretion in such patients: normal, paradoxical and areactive. The blood level of beta 2-microglobulin was raised in 65% of cases in the paradoxical response, in 34.5% in the normal response and in 0.6% in the areactive response. The data obtained suggested heterogeneity of the mechanisms of development of vascular complications in diabetes mellitus, type II.
Livshits
I B
IB
Kostiuk
K L
KL
Sherstiuk
G B
GB
D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications; D003925:Diabetic Angiopathies / Q000097:blood* / Q000209:etiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D014667:Vasopressins / Q000097:blood*; D001613:beta 2-Microglobulin / Q000378:metabolism*
D001613:beta 2-Microglobulin; D014667:Vasopressins
Soderzhanie vazopressina i beta2-mikroglobulina v krovi bol'nykh sakharnym diabetom II tipa s nalichiem mikroangiopatiĭ.