Central nervous system AIDS.
The retrovirus that causes the acquired immunodeficiency syndrome (AIDS) has two targets: the immune system and the nervous system. Central nervous system (CNS) manifestations of AIDS are protean. This review describes the opportunistic infections and malignancies that affect the nervous system in AIDS, and discusses the syndromes resulting from primary infection of the CNS by the AIDS virus. Possible mechanisms of CNS injury are cited as well as potential predictors of neurologic expression of AIDS.
Tucker
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Department of Neurology, University Hospitals of Cleveland, Case Western Reserve University, OH 44106.
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D008223:Lymphoma / Q000150:complications* / Q000473:pathology; D009422:Nervous System Diseases / Q000150:complications* / Q000473:pathology; D009894:Opportunistic Infections / Q000150:complications* / Q000473:pathology