title: Effect of carbonyl cyanide m-chlorophenylhydrazone on Escherichia coli halotolerance.
abstract: The growth-inhibitory effect of carbonyl cyanide m-chlorophenylhydrazone (CCCP) was less on members of the family Enterobacteriaceae (halotolerant organisms) than it was on species of Vibrio (moderately halophilic organisms). When sodium chloride concentration increased from 0.5 to 0.85 M, this effect was more pronounced for Escherichia coli; it remained relatively stable for Vibrio spp. The effect of carbonyl cyanide m-chlorophenylhydrazone was antagonized by the addition of glycine betaine or proline or by growth in a rich medium.
authors.affiliation: Laboratoire de Microbiologie Pharmaceutique, Université de Rennes I, France.
authors.forename: M
authors.initials: M
authors.lastname: Ghoul
authors.forename: M
authors.initials: M
authors.lastname: Pommepuy
authors.forename: A
authors.initials: A
authors.lastname: Moillo-Batt
authors.forename: M
authors.initials: M
authors.lastname: Cormier
mesh_terms: D002258:Carbonyl Cyanide m-Chlorophenyl Hydrazone / Q000494:pharmacology*; D003470:Culture Media; D004926:Escherichia coli / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D007709:Klebsiella / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism; D009570:Nitriles / Q000494:pharmacology*; D009997:Osmotic Pressure; D012475:Salmonella / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism; D012623:Seawater; D012965:Sodium Chloride / Q000378:metabolism*; D014733:Vibrio / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism; D014871:Water Microbiology
chemical_list: D003470:Culture Media; D009570:Nitriles; D012965:Sodium Chloride; D002258:Carbonyl Cyanide m-Chlorophenyl Hydrazone