[Adenosine deaminase activity in the cerebrospinal fluid of children with acute lymphoblastic leukemia].
The activity of adenosine deaminase was determined in the cerebrospinal fluid in children with acute lymphoblastic leukaemia in various phases. It was found that an evident rise of this activity occurred during leukaemic meningeal involvement as compared with the initial phase the disease or with the first complete remission. After an episode of recurrent cerebrospinal leukaemia the activity of the enzyme was also higher than during the first complete remission. Such high values as during meningeal leukaemia were not found in inflammatory cerebrospinal fluid which suggests that determinations of this enzyme could be useful for differentiation of leukaemic infiltrations in the central nervous system against lymphocytic meningitis.
Lastowska
M
M
D000243:Adenosine Deaminase / Q000134:cerebrospinal fluid*; D002648:Child; D006801:Humans; D009700:Nucleoside Deaminases / Q000134:cerebrospinal fluid*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000201:enzymology*
D009700:Nucleoside Deaminases; D000243:Adenosine Deaminase
Aktywność dezaminazy adenozyny w płynie mózgowordzeniowym u dzieci z ostra białaczka limfoblastyczna.