Update on NSAIDS in the elderly.
Nonsteroidal anti-inflammatory drugs (NSAIDs) can effectively reduce pain and inflammation. Although these agents are potent inhibitors of prostaglandin synthesis, they probably have other effects on the inflammatory process. NSAIDs produce a number of side effects, particularly in elderly patients. Understanding the effects of aging on drug pharmacokinetics will help minimize these complications.
Sack
K E
KE
University of California, San Francisco.
D000368:Aged; D000375:Aging; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000493:pharmacokinetics; D006801:Humans; D012459:Salicylates / Q000009:adverse effects / Q000493:pharmacokinetics
D000894:Anti-Inflammatory Agents, Non-Steroidal; D012459:Salicylates