title: [Neonatal levels of 17-hydroxyprogesterone--early diagnosis of adrenogenital syndrome].
abstract: The authors submit the results of 17-hydroxyprogesterone estimations in serum of healthy neonates after birth and during the first days of life. The 17-hydroxyprogesterone level declines markedly after birth to the fourth day after birth in infants of both sexes. The levels recorded in infants above 4 days (8.4 +/- 3.4 nmol/l) will serve as normal values in the diagnosis of adrenogenital syndrome caused by the block of 21-hydroxylase steroids. Estimation of 17-hydroxyprogesterone in umbilical blood cannot be used for the diagnosis of AGS in neonates.
authors.forename: J
authors.initials: J
authors.lastname: Sulcová
authors.forename: H
authors.initials: H
authors.lastname: Tichá
authors.forename: O
authors.initials: O
authors.lastname: Wiererová
mesh_terms: D019326:17-alpha-Hydroxyprogesterone; D000312:Adrenal Hyperplasia, Congenital / Q000097:blood / Q000175:diagnosis*; D005260:Female; D006801:Humans; D006908:Hydroxyprogesterones / Q000097:blood*; D007231:Infant, Newborn; D008297:Male
chemical_list: D006908:Hydroxyprogesterones; D019326:17-alpha-Hydroxyprogesterone
vernacular_title: Neonatální hladiny 17-hydroxyprogesteronu--raná diagnostika adrenogenitálního syndromu.