title: [Basic research on endomyocardial biopsy].
abstract: To determine the risk of biopsy in different parts of heart and the artifacts of histomorphology, right heart endomyocardial biopsy in eight dogs were done. The result showed no tamponade occurred even 53 pieces of heart muscles were got from right ventricular free wall. In contrast, biopsies on right atrial free wall had higher risk in causing tamponade. It was confirmed by autopsy and histomorphology that endomyocardial biopsy could cause heart muscle damage. The artifacts caused by biopsy of normal beating heart muscle include: contraction bands (21.8%), widen of intracellular space (100%), interstitial edema (78%) and interstitial bleeding (53%). The results of the patients of right ventricular endomyocardial biopsy may provide practical value in the application of endomyocardial biopsy.
authors.forename: Z M
authors.initials: ZM
authors.lastname: Li
authors.forename: Y Y
authors.initials: YY
authors.lastname: Xu
authors.forename: G Y
authors.initials: GY
authors.lastname: Zhu
mesh_terms: D000818:Animals; D001706:Biopsy / Q000009:adverse effects; D002305:Cardiac Tamponade / Q000209:etiology; D004285:Dogs; D004699:Endocardium / Q000473:pathology*; D009206:Myocardium / Q000473:pathology*