Ciprofloxacin for the treatment of osteomyelitis: a review.
The authors review the use of ciprofloxacin, a new oral quinolone antibiotic, for the treatment of bone infections. The article discusses the spectrum of activity, pharmacokinetics, and toxicity of the quinolone agents. The authors also provide a detailed discussion of the efficacy of ciprofloxacin for osteomyelitis in animal studies and human trials.
Hessen
M T
MT
Department of Medicine, Medical College of Pennsylvania, Philadelphia.
Levison
M E
ME
D000818:Animals; D001419:Bacteria / Q000187:drug effects; D002939:Ciprofloxacin / Q000009:adverse effects / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D004352:Drug Resistance, Microbial; D006801:Humans; D010019:Osteomyelitis / Q000188:drug therapy*
D002939:Ciprofloxacin