Relationship between bacteria and IgE.
In this preliminary report, we describe our inability to induce IgE antibody to a well-characterized bacterial component, the membrane proteoglycan of Klebsiella pneumoniae and its major protein fraction FIII-B in BALB/c mice. In contrast, an immunomodulatory effect of membrane proteoglycan of K. pneumoniae on the IgE and IgG antibody responses to ovalbumin could be demonstrated.
Levy
D A
DA
Centre d'Immunologie et de Biologie Pierre-Fabre, Castres, France.
Dorat
A
A
Pinel
A M
AM
Normier
G
G
D'Hinterland
L D
LD
David
B
B
D000485:Allergens / Q000276:immunology; D000818:Animals; D005260:Female; D007073:Immunoglobulin E / Q000276:immunology*; D007074:Immunoglobulin G / Q000276:immunology; D007711:Klebsiella pneumoniae / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D010047:Ovalbumin / Q000276:immunology; D011509:Proteoglycans / Q000276:immunology*
D000485:Allergens; D007074:Immunoglobulin G; D011509:Proteoglycans; D007073:Immunoglobulin E; D010047:Ovalbumin