A retrospective review of the effects of one year of triamcinolone acetonide aerosol treatment on the growth patterns of asthmatic children.
Retrospective growth data were evaluated for 82 asthmatic children (59% dependent on oral corticosteroids) receiving triamcinolone acetonide aerosol for 1 year. Two-thirds of the steroid-dependent patients discontinued oral steroids. Triamcinolone acetonide did not adversely affect height or weight gain, although steroid-dependent asthmatics gained less weight than predicted, probably due to diminished fluid retention and appetite associated with decreased oral steroid doses and resolution of cushingoid features.
Brown
D C
DC
Rorer Central Research, Horsham, Pennsylvania.
Savacool
A M
AM
Letizia
C M
CM
D000293:Adolescent; D000336:Aerosols; D001249:Asthma / Q000188:drug therapy / Q000503:physiopathology*; D001827:Body Height / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D002648:Child; D005260:Female; D006128:Growth / Q000187:drug effects*; D006801:Humans; D008297:Male; D015337:Multicenter Studies as Topic; D011241:Prednisone / Q000627:therapeutic use; D012189:Retrospective Studies; D014222:Triamcinolone Acetonide / Q000008:administration & dosage* / Q000627:therapeutic use
D000336:Aerosols; D014222:Triamcinolone Acetonide; D011241:Prednisone