title: Vibratory acoustic stimulation in 26- to 32-week, small-for-gestational-age fetus.
abstract: Seven pregnant women with early-onset (less than 32 weeks' gestation) intrauterine growth retardation were studied to examine fetal heart rate and fetal activity patterns after vibratory acoustic stimulation. All studies were done between 26 and 32 weeks' gestation. All fetuses but one were not acidotic at birth. There was a reduced time during which accelerations (50% less), long-term fetal heart rate variability (25% less), and body movements (60% less) occurred in small-for-gestational-age fetuses compared with these times in age-matched normally grown fetuses. Fetal heart rate and fetal activity patterns were not significantly altered after stimulation with the electronic artificial larynx. We hypothesized that severe, early-onset (less than 32 weeks' gestation), chronic nutritional deprivation of human fetuses is associated with a delay in the functional maturation of fetal sensory receptors.
authors.affiliation: Department of Obstetrics and Gynecology, Lawson Research Institute, University of Western Ontario, London, Canada.
authors.forename: R
authors.initials: R
authors.lastname: Gagnon
authors.forename: C
authors.initials: C
authors.lastname: Hunse
authors.forename: L
authors.initials: L
authors.lastname: Carmichael
authors.forename: J
authors.initials: J
authors.lastname: Patrick
mesh_terms: D000161:Acoustic Stimulation; D000704:Analysis of Variance; D005260:Female; D005317:Fetal Growth Retardation / Q000503:physiopathology*; D005324:Fetal Movement; D006340:Heart Rate, Fetal; D006801:Humans; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D011296:Prenatal Diagnosis; D012119:Respiration; D014463:Ultrasonography; D014732:Vibration