Malignant mesothelioma in infancy.
Malignant mesothelioma in infancy has rarely been reported in the literature. A 19-month-old female infant with massive malignant epithelial mesothelioma of the pleura underwent postmortem examination. Histochemical study confirmed the diagnosis by revealing acid mucosubstance in the tumor, which was removed by hyaluronidase. The tumor cell had clear cytoplasm that was positive for periodic acid-Schiff staining, which could be totally abolished by diastase. This correlated well with the electron microscopic finding that there had been massive accumulation of glycogen in the cytoplasm. There was no information about environmental exposure to asbestos.
Lin-Chu
M
M
Department of Laboratory Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
Lee
Y J
YJ
Ho
M Y
MY
D000230:Adenocarcinoma / Q000175:diagnosis; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis / Q000473:pathology*; D010997:Pleural Neoplasms / Q000175:diagnosis / Q000473:pathology*