Cyclosporine-induced lymphoma following a unilateral lung transplant. The Toronto Lung Transplant Group.
Lymphomas are a well-known complication of therapy following organ transplantation. To date we have seen one lymphoma develop in a group of 24 patients who have undergone single or double lung transplantation. We report a 16-year-old man who developed multiple, rapidly appearing pulmonary nodules four months following transplantation. The Epstein-Barr virus and immunosuppressant drugs such as cyclosporine A have been implicated in the pathogenesis of this patient's rapidly progressive and fatal course.
Rappaport
D C
DC
Department of Radiology, Toronto General Hospital, Ontario.
Weisbrod
G L
GL
Herman
S J
SJ
D000293:Adolescent; D003524:Cyclosporins / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D016040:Lung Transplantation; D008223:Lymphoma / Q000139:chemically induced* / Q000000981:diagnostic imaging; D008297:Male; D008722:Methods; D011658:Pulmonary Fibrosis / Q000601:surgery; D011859:Radiography
D003524:Cyclosporins