title: Pituitary abscess after autologous bone marrow transplantation.
abstract: The first case of pituitary abscess arising in a patient during recovery from autologous bone marrow transplantation is reported. A 31-year-old man with a 9 month history of T-cell lymphoma died suddenly more than 60 days after successful treatment with high-dose cyclophosphamide, total body irradiation, and autologous bone marrow infusion. Autopsy revealed a pituitary abscess associated with clinically silent sphenoid sinusitis. Unique aspects of this case are presented and clinical and pathologic features of pituitary abscess are reviewed. Although rare, pituitary abscess may complicate recovery from bone marrow transplantation.
authors.affiliation: Department of Medicine, Wilford Hall USAF Medical Center, San Antonio, TX 78236.
authors.forename: R S
authors.initials: RS
authors.lastname: Leff
authors.forename: R L
authors.initials: RL
authors.lastname: Martino
authors.forename: W J
authors.initials: WJ
authors.lastname: Pollock
authors.forename: W A
authors.initials: WA
authors.lastname: Knight
mesh_terms: D000038:Abscess / Q000209:etiology* / Q000473:pathology; D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D016026:Bone Marrow Transplantation; D003131:Combined Modality Therapy; D006801:Humans; D008223:Lymphoma / Q000188:drug therapy / Q000628:therapy; D008297:Male; D010900:Pituitary Diseases / Q000209:etiology* / Q000473:pathology; D011183:Postoperative Complications; D012852:Sinusitis / Q000150:complications; D013601:T-Lymphocytes; D014182:Transplantation, Autologous
chemical_list: D000970:Antineoplastic Agents