Placental phospholipase A2 activities in pre-eclampsia.
Phospholipase A2 activity was significantly increased in placental homogenates from 22 patients with preeclampsia in comparison to placental homogenates from women with uncomplicated pregnancy. Such an abnormality may be responsible for a altered release of free arachidonic acid, thus playing a major role in the pathogenesis of this syndrome.
Jendryczko
A
A
Tomala
J
J
Drózdz
M
M
Włoch
S
S
D000293:Adolescent; D000328:Adult; D004789:Enzyme Activation; D005260:Female; D006801:Humans; D010740:Phospholipases / Q000378:metabolism*; D010741:Phospholipases A / Q000378:metabolism*; D054467:Phospholipases A2; D010920:Placenta / Q000201:enzymology*; D011225:Pre-Eclampsia / Q000201:enzymology*; D011247:Pregnancy
D010740:Phospholipases; D010741:Phospholipases A; D054467:Phospholipases A2