Clinical evaluation of ketotifen for chronic urticaria: multicenter double-blind comparative study with clemastine.
A double-blind study was performed in 305 patients to compare ketotifen capsule and clemastine tablet. Ketotifen alleviated eruption and itching to a significantly greater extent than clemastine. The utility rating of ketotifen was significantly higher than that of clemastine.
Kamide
R
R
Department of Dermatology, Jikei University, School of Medicine, Tokyo, Japan.
Niimura
M
M
Ueda
H
H
Imamura
S
S
Yamamoto
S
S
Yoshida
H
H
Kukita
A
A
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002908:Chronic Disease; D002974:Clemastine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007665:Ketotifen / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011759:Pyrrolidines / Q000627:therapeutic use*; D014581:Urticaria / Q000188:drug therapy*
D011759:Pyrrolidines; D002974:Clemastine; D007665:Ketotifen