title: [Dipivefrin: its mechanism of action, clinical efficacy and good tolerance].
abstract: Dipivefrin (DPE) is the first prodrug in general use in ophthalmology. We will discuss the metabolism of DPE to epinephrine within the eye, and the efficacy and safety of DPE in the treatment of elevated intraocular pressure. In addition, we will address the incidence of adverse systemic effects, ocular tolerance and allergy, and the ocular hypotensive efficacy when DPE is used alone or in combination with other antiglaucoma medications.
authors.forename: D G
authors.initials: DG
authors.lastname: Harper
authors.forename: G D
authors.initials: GD
authors.lastname: Novack
authors.forename: L R
authors.initials: LR
authors.lastname: Borrmann
authors.forename: M J
authors.initials: MJ
authors.lastname: Branin
mesh_terms: D004837:Epinephrine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D005901:Glaucoma / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D014792:Visual Acuity / Q000187:drug effects
chemical_list: C015173:dipivefrin; D004837:Epinephrine
vernacular_title: Dipivéfrine, son mécanisme d'action, son efficacité clinique, sa bonne tolérance.