[Transdermal scopolamine to prevent postoperative nausea and vomiting after uterine curettage and termination of pregnancy. A double-blind clinically controlled study with placebo].
A randomized double-blind clinically controlled investigation with a placebo was undertaken to investigate the prophylactic effect of transdermal scopolamine on postoperative nausea and vomiting after dilatation and curettage and termination of pregnancy. No significant difference was found between the placebo and transdermal scopolamine. On the other hand, the patients in the scopolamine group had significantly more postoperative discomforts which were attributable to the anticholinergic effect of scopolamine. Transdermal scopolamine cannot be recommended for the prophylaxis of postoperative nausea and vomiting following uterine curettage and termination of pregnancy.
Jespersen
T W
TW
Koch
J
J
Anker-Møller
E
E
Spangsberg
N L
NL
Johansen
U T
UT
Grydehøj
P
P
D000028:Abortion, Induced; D000328:Adult; D002986:Clinical Trials as Topic; D004107:Dilatation and Curettage; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D009325:Nausea / Q000209:etiology / Q000517:prevention & control*; D011183:Postoperative Complications / Q000517:prevention & control*; D011247:Pregnancy; D011897:Random Allocation; D012601:Scopolamine / Q000008:administration & dosage*; D014839:Vomiting / Q000209:etiology / Q000517:prevention & control*
D012601:Scopolamine
Transdermal skopolamin som profylakse mod postoperativ kvalme ved abrasio uteri og abortus provocatus. En dobbeltblind klinisk kontrolleret undersøgelse med placebo.