Antibiotic beads in the management of surgical infections.
Polymethyl methacrylate antibiotic beads have been used successfully in the treatment of surgical infections. Presented are their mechanism of action, their use in experimental and clinical settings, and their complications.
Calhoun
J H
JH
Department of Surgery, University of Texas Medical Branch, Galveston 77550.
Mader
J T
JT
D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000493:pharmacokinetics; D001843:Bone Cements; D006801:Humans; D007595:Joint Prosthesis; D008768:Methylmethacrylates; D010019:Osteomyelitis / Q000188:drug therapy / Q000601:surgery; D013530:Surgical Wound Infection / Q000517:prevention & control*
D000900:Anti-Bacterial Agents; D001843:Bone Cements; D008768:Methylmethacrylates