A Gompertz age-specific mortality rate model of aging: modification by dietary restriction in rats.
A Gompertz age-specific mortality rate model characterizing actuarial effects of food restriction in rats was developed based on mortality data from the study of Yu et al. (J. Gerontol. 40: 657-670, 1985). Results indicated that in the presence of adequate nutrition, food restriction reduces the aging rate parameter in a consistent manner, regardless of the age at which food restriction is initiated.
Neafsey
P J
PJ
Tufts University School of Medicine, Boston, Massachusetts.
Boxenbaum
H
H
Ciraulo
D A
DA
Fournier
D J
DJ
D000375:Aging / Q000502:physiology*; D000818:Animals; D004032:Diet; D008297:Male; D008954:Models, Biological; D009026:Mortality; D016016:Proportional Hazards Models; D051381:Rats; D011916:Rats, Inbred F344