[In vitro study of propamidine isethionate: value in the follow-up of Acanthamoeba amebic keratitis].
Propamidine isethionate eye drops is one of the treatments which are used against amebic keratitis with Acanthamoeba. Several strains of Acanthamoeba, having been tested with this drug during several weeks, did show off a resistance. The authors come to the conclusion that in vitro sensitivity must be examined and therapy must be perfect since the beginning.
Paniagua-Crespo
E
E
Laboratoire de Parasitologie, Faculté de Médecine de Brest.
Hasle
D P
DP
Aouizerate
F
F
Volant
A
A
Simitzis-Le Flohic
A M
AM
D000048:Acanthamoeba / Q000187:drug effects*; D015823:Acanthamoeba Keratitis / Q000188:drug therapy; D000578:Amidines / Q000494:pharmacology*; D000818:Animals; D000981:Antiprotozoal Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001550:Benzamidines / Q000494:pharmacology* / Q000627:therapeutic use; D004351:Drug Resistance; D006801:Humans
D000578:Amidines; D000981:Antiprotozoal Agents; D001550:Benzamidines; C046651:propamidine isethionate
Etude in vitro de l'iséthionate de propamidine: intérêt dans le suivi des kératites amibiennes à Acanthamoeba.