[Influence of brachytherapy on the behavior of immunologic circulating complexes in the blood serum of patients with cervix cancer].
Applying the EA and EAC rosettes production inhibition method the appearance and levels of immunologic circulating complexes (CI) in the blood serum of 32 patients with cancer of the uterine cervix and in 100 healthy persons have been evaluated. Immunocomplexes have been examined prior to the initiation of brachytherapy and after three successive applications of radioactive cesium isotope (137Cs). Three successive application of the radioisotope contained and in the uterine probe have been used and a dose up to 2000 cGy in 16-18 hours given on each application. It has been shown that prior to treatment and in some stages of clinical advancement the levels of CI evaluated by two tests are significantly higher as compared with controls. Significant increase of CI levels after successive application of cesium has been also noted. The appearance of CI in patients with cervical cancer indicates the presence of tumor-specific and/or viral antigens in such patients. The elevation of CI levels after cesium application may be result of accelerated release of antigens in the course of brachytherapy.
Dziewulska-Bokiniec
A
A
Domaradzka-Woźniak
A
A
Sztaba-Kania
M
M
Krutysza
M
M
D000328:Adult; D000368:Aged; D000936:Antigen-Antibody Complex / Q000097:blood*; D001918:Brachytherapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D002583:Uterine Cervical Neoplasms / Q000276:immunology / Q000473:pathology / Q000532:radiotherapy*
D000936:Antigen-Antibody Complex
Wpływ brachyterapii na zachowanie sie krazacych kompleksów immunologicznych w surowicy chorych na raka szyjki macicy.