title: Combined therapy of enuresis alarm and desmopressin in the treatment of nocturnal enuresis.
abstract: Twenty-eight children with primary nocturnal enuresis were blindly allocated at random to a combination of enuresis alarm and 20 micrograms intranasal desmopressin or alarm and placebo for 2 weeks. Patients received the other therapy after a 2-week treatment-free period. The combined treatment of desmopressin and alarm showed 5.1 +/- 0.4 (mean +/- SEM) dry nights per week and resulted in significantly more dry nights per week during the 2 weeks of observation than placebo and alarm (4.1 +/- 0.4, P less than 0.05).
authors.affiliation: Zuiderziekenhuis Rotterdam, Afdeling Kindergeneeskunde, The Netherlands.
authors.forename: R N
authors.initials: RN
authors.lastname: Sukhai
authors.forename: J
authors.initials: J
authors.lastname: Mol
authors.forename: A S
authors.initials: AS
authors.lastname: Harris
mesh_terms: D000293:Adolescent; D002648:Child; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D003213:Conditioning, Psychological; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use*; D004311:Double-Blind Method; D004775:Enuresis / Q000188:drug therapy / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D011897:Random Allocation
chemical_list: D003894:Deamino Arginine Vasopressin