Skin and mucosal lesions associated with cyclosporin A therapy: report of a case.
A 16-year-old boy developed bullous lesions on fingers, ears, tongue, and buccal mucosa as well as cauliflower-like growths on the epiglottis and vocal cords 1 1/2 years after a second renal transplantation and exposure to sunlight while receiving cyclosporin A (CsA). Withdrawal of CsA was followed by complete resolution of skin and mucosal lesions. A predisposition for adverse reactions to CsA is suggested, as additional side effects of CsA therapy were also present.
Feldhoff
C M
CM
Department of Pediatric Nephrology, University Hospitals, Essen, FRG.
Reber
T
T
Drachman
R
R
Drukker
A
A
D000293:Adolescent; D003524:Cyclosporins / Q000009:adverse effects*; D006801:Humans; D016030:Kidney Transplantation; D007818:Laryngeal Diseases / Q000139:chemically induced; D007820:Laryngeal Mucosa / Q000187:drug effects*; D007830:Larynx / Q000187:drug effects*; D008297:Male; D009059:Mouth Diseases / Q000139:chemically induced; D009061:Mouth Mucosa / Q000187:drug effects*; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced*
D003524:Cyclosporins