Visual function in multiple sclerosis.
126 patients with multiple sclerosis and normal visual acuity were submitted to a battery of tests of visual function. The investigation included visual evoked potential, contrast sensitivity by three methods, and a segment of the Farnsworth-Munsell 100 Hue test. 22 of the patients gave a history of unilateral acute optic neuritis and in these the abnormalities were greater in degree. Contrast sensitivity emerged as the most useful test and was abnormal in 92.2% of eyes. Visual evoked potential was delayed in 35.6% and colour vision was abnormal in less than a third. In general, contrast sensitivity was depressed at all frequencies and most of the abnormalities could be identified by testing at a single frequency of 4 cycles/degree.
Ashworth
B
B
Department of Clinical Neurosciences, University of Edinburgh.
Aspinall
P A
PA
Mitchell
J D
JD
D000208:Acute Disease; D000328:Adult; D003118:Color Perception; D015350:Contrast Sensitivity; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000150:complications* / Q000503:physiopathology; D009902:Optic Neuritis / Q000209:etiology; D014786:Vision Disorders / Q000209:etiology* / Q000503:physiopathology; D014792:Visual Acuity