Primary structure of an oligomeric antigen of Treponema pallidum.
The properties and sequence of an oligomeric antigen of Treponema pallidum are presented. Antigen C1-5 assembles into oligomers of 140,000 and greater. The nucleotide sequence predicts an open reading frame for a protein monomer of 19,400, confirmed by amino-terminal sequencing of the recombinant antigen.
Walfield
A M
AM
Syntro Corporation, San Diego, California 92121.
Roche
E S
ES
Zounes
M C
MC
Kirkpatrick
H
H
Wild
M A
MA
Textor
G
G
Tsai
P K
PK
Richardson
C
C
D000595:Amino Acid Sequence; D000818:Animals; D000942:Antigens, Bacterial / Q000235:genetics / Q000302:isolation & purification*; D001483:Base Sequence; D003001:Cloning, Molecular; D004926:Escherichia coli / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D008970:Molecular Weight; D011487:Protein Conformation; D011817:Rabbits; D011994:Recombinant Proteins / Q000302:isolation & purification; D014210:Treponema pallidum / Q000032:analysis / Q000276:immunology*
D000942:Antigens, Bacterial; D011994:Recombinant Proteins