[Significance of anti-gluten IgA levels for detection and monitoring of celiac disease].
Diagnosis of coeliac disease rests in jejunal biopsy. This is recognised as a traumatic examination which today may perhaps be replaced by a biological test produced by Pharmacia in which the anti-gluten IgA is measured by the ELISA method. The sensitivity of the test reaches 100% and the specificity to 96%. This biological test makes it possible to follow the development of the coeliac illness under diet, since the anti-gluten IgA diminishes significantly, often to the normal level.
Sabbah
A
A
Laboratoire d'Immuno-Allergologie, C.H.U., Angers.
Desoubry
L
L
Heulin
M G
MG
D000328:Adult; D002446:Celiac Disease / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D002648:Child; D005983:Glutens / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007070:Immunoglobulin A / Q000032:analysis*; D007413:Intestinal Mucosa / Q000473:pathology; D008875:Middle Aged; D015166:Monitoring, Immunologic
D007070:Immunoglobulin A; D005983:Glutens
Intérêt du dosage des IgA antigluten comme test de dépistage et de suivi de la maladie coeliaque.