title: Scintigraphy in a patient with complicated osteopetrosis.
abstract: Skeletal, reticuloendothelial and renal images were obtained on a patient with osteopetrosis using Tc-99m MDP, Tc-99m HSA millimicrospheres and Tc-99m DTPA respectively. The bone scan showed increased uptake in multiple fracture sites, in the frontal bone, and in the splayed metaphyses of long bones while the remainder of the skeleton appeared normal. Reticuloendothelial images demonstrated an absence of bone marrow activity, hepatosplenomegaly and a site of extramedullary hematopoiesis. A renogram demonstrated a left kidney displaced and distorted by the massive splenomegaly.
authors.affiliation: Department of Nuclear Medicine, Groote Schuur Hospital, Cape Town, South Africa.
authors.forename: B K
authors.initials: BK
authors.lastname: Adams
mesh_terms: D000328:Adult; D050723:Fractures, Bone / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D007674:Kidney Diseases / Q000000981:diagnostic imaging / Q000209:etiology; D008297:Male; D012157:Mononuclear Phagocyte System / Q000000981:diagnostic imaging; D009942:Organometallic Compounds / Q000627:therapeutic use; D010022:Osteopetrosis / Q000150:complications / Q000000981:diagnostic imaging*; D004369:Pentetic Acid / Q000627:therapeutic use; D011877:Radionuclide Imaging; D013667:Technetium; D013668:Technetium Tc 99m Aggregated Albumin; D013669:Technetium Tc 99m Medronate; D016284:Technetium Tc 99m Pentetate
chemical_list: D009942:Organometallic Compounds; D013668:Technetium Tc 99m Aggregated Albumin; D013667:Technetium; D004369:Pentetic Acid; D016284:Technetium Tc 99m Pentetate; D013669:Technetium Tc 99m Medronate