Comparison of single-dose cefmetazole and cefotetan prophylaxis in women undergoing primary caesarean section.
The efficacies of a single 2 g intra-operative iv dose of cefmetazole or cefotetan in women undergoing non-elective Caesarean section were compared. Thirty-six women (18 in each group) completed the double-blind protocol. Both antibiotics were equally effective as agents for prophylaxis of post-Caesarean infections. Combined data suggest that routine multi-dose antibiotic prophylaxis regimens could be replaced by a single dose regimen.
Galask
R P
RP
Department of Microbiology, University of Iowa College of Medicine, Iowa City.
Weiner
C
C
Petzold
C R
CR
D000293:Adolescent; D000328:Adult; D015311:Cefmetazole / Q000627:therapeutic use*; D015313:Cefotetan / Q000627:therapeutic use*; D002585:Cesarean Section; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D011247:Pregnancy; D011292:Premedication; D011897:Random Allocation; D013530:Surgical Wound Infection / Q000382:microbiology / Q000517:prevention & control*
D015311:Cefmetazole; D015313:Cefotetan