title: [Influences from the treatment of thyroid disease and diabetes mellitus on breast cancer prognosis].
abstract: We have studied influences from the treatment of a thyroid disease and diabetes mellitus on breast cancer prognosis. Forty-one breast cancer patients with a thyroid disease and 16 cases with diabetes mellitus under medical treatment have been investigated. There was no special clinicopathological characteristics found in patients with a thyroid disease. The 5-year relapse-free survival rate (5 Y-RFS) of these patients was 95% and the 5-year overall survival rate (5 Y-OS) was 100%. Therefore, the presence of a thyroid disease showed no significant effect on the survival of breast cancer patients. In contrast, the prognosis of a group of diabetes mellitus was relatively poor, the 5 Y-RFS showing 75% and 5 Y-OS 81%. A significantly worse survival rate was found in cases of insulin treated subgroups compared to orally treated patients.
authors.affiliation: Dept. of Surgery, National Cancer Center Hospital.
authors.forename: T
authors.initials: T
authors.lastname: Fukutomi
authors.forename: T
authors.initials: T
authors.lastname: Nanasawa
authors.forename: H
authors.initials: H
authors.lastname: Yamamoto
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000150:complications* / Q000401:mortality; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007328:Insulin / Q000009:adverse effects / Q000627:therapeutic use; D008875:Middle Aged; D011379:Prognosis; D013959:Thyroid Diseases / Q000150:complications / Q000628:therapy*
chemical_list: D007328:Insulin