title: [The enhanced efficacy of specific hyposensitization in patients with recurrent uveitis].
abstract: The purpose of a new method elaborated for treatment of allergic inflammation of the eye is to rise effectiveness of treatment and to prevent exacerbation of allergic inflammation by means of increasing the accuracy of determining the therapeutic allergen dilution when conducting specific hyposensitization. This is achieved in the following way: in addition to control, when conducting allergometric titration, the syringe needle is introduced intracutaneously without subsequent administration of the allergen. In respective terms, the thermometry of skin is made in the sites of administration of different allergen dilutions and in the control site. Considering the minimum hyperthermia in the site of administration of the highest allergen dilution as compared with the control site, the therapeutic allergen dilution is chosen. This method of treatment was used in 38 patients (54 eyes) with recurrent uveitis and proved to be highly effective in 34 patients (50 eyes), i.e. in 92%. In remote terms of observation, no further recurrences were recorded in 65% of cases.
authors.forename: V V
authors.initials: VV
authors.lastname: Savko
authors.forename: I A
authors.initials: IA
authors.lastname: Safronenkova
mesh_terms: D000328:Adult; D000485:Allergens / Q000008:administration & dosage; D002908:Chronic Disease; D003888:Desensitization, Immunologic / Q000379:methods*; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D014605:Uveitis / Q000503:physiopathology / Q000628:therapy*; D014792:Visual Acuity / Q000502:physiology
chemical_list: D000485:Allergens
vernacular_title: Povyshenie éffektivnosti spetsificheskoĭ giposensibilizatsii bol'nykh retsidiviruiushchimi uveitami.