title: [Histopathological studies of periodontal tissue reactions to perforations in the furcation of dogs' teeth treated with cyanoacrylate cement (FH Cement)].
abstract: In the previous study (Shikwa Gakuho, 85: 413-451, 1985.), Morinaga reported on the histopathology of furcation perforations treated with ethyl cyanoacrylate and showed that, because of its properties, this material cannot be expected to effect a permanent blockade. It did not, however, irritate the wound. The purpose of this study is to investigate the effects of a new cyanoacrylate cement (FH Cement) when applied to furcation perforations. Subjects were 25 mandibular and maxilla premolars and molars obtained from 3 adult dogs. The method used in the study was as follows. After administration of pentobarbital-sodium general anesthesia, the pulp chamber was opened by means of a high-speed air turbine fitted with a diamond point. According to usual procedures, the pulp was removed, and the main root canal was filled. Next the floor of the pulp chamber was deliberately perforated by means of a 1mm round bur that had been previously sterilized in advance pouring a physiological sodium chloride solution at the same time. The perforated areas were then washed with a same solution, wiped, and dried with aseptic cotton pellets. They were then stuffed with cyanoacrylate cement. The cavity was lined with gutta-percha temporary stopping, and the remainder of the cavity was filled with silver amalgam. At periods of 1, 2, 4, 8 and 12 weeks after the operation, the animals were sacrificed by means of electricity under general anesthesia. The jaw bones were removed, fixed, decalcified, and embedded in celloidin. Longitudinal sections were stained with hematoxylin-eosin. Results 1. Periodontal tissues around perforated sites were healed by means of scar tissue, though suppuration occurred in a few cases. 2. Hard tissue was appended to the teeth in a small number of cases. 3. Repair of the alveolar bone was observed in the damaged site in about half of all cases. From the result mentioned above, cyanoacrylate cement (FH Cement) was seemed to did not close the site perforation for it self, but was not a stimulant to wound, in case of appropriate blockade.
authors.forename: K
authors.initials: K
authors.lastname: Morinaga
authors.forename: M
authors.initials: M
authors.lastname: Furusawa
authors.forename: M
authors.initials: M
authors.lastname: Kitamura
authors.forename: H
authors.initials: H
authors.lastname: Sato
authors.forename: H
authors.initials: H
authors.lastname: Watanabe
authors.forename: S
authors.initials: S
authors.lastname: Yokoya
authors.forename: K
authors.initials: K
authors.lastname: Nakagawa
authors.forename: Y
authors.initials: Y
authors.lastname: Asai
mesh_terms: D000818:Animals; D003487:Cyanoacrylates / Q000494:pharmacology*; D003738:Dental Cements / Q000494:pharmacology; D004285:Dogs; D010519:Periodontium / Q000187:drug effects / Q000473:pathology*; D012389:Root Canal Obturation / Q000379:methods
chemical_list: D003487:Cyanoacrylates; D003738:Dental Cements