title: Radiotherapy of the central nervous system in acute leukemia.
abstract: The central nervous system (CNS) is a site of occult and overt involvement with acute lymphoblastic leukemia (ALL) in children. Prophylactic treatment of the cranial and spinal meninges can significantly reduce the incidence of CNS relapse. This review addresses the issues associated with the role of radiation therapy in the treatment of the CNS in ALL.
authors.affiliation: Department of Radiology, University Hospitals of Cleveland, Case Western Reserve University School of Medicine, Ohio 44106.
authors.forename: L J
authors.initials: LJ
authors.lastname: Novak
mesh_terms: D001932:Brain Neoplasms / Q000473:pathology / Q000517:prevention & control / Q000662:veterinary*; D002648:Child; D006050:Gold Radioisotopes / Q000627:therapeutic use; D006801:Humans; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000532:radiotherapy*; D011832:Radiation Injuries
chemical_list: D006050:Gold Radioisotopes