Subacute cutaneous lupus erythematosus during PUVA therapy for psoriasis: case report and review of the literature.
Lesions typical of subacute cutaneous lupus erythematosus developed in an elderly woman after 6 months of PUVA (8-methoxypsoralen and longwave ultraviolet light) therapy for psoriasis. Pancytopenia, antibodies to double-stranded DNA, and hypocomplementemia developed concurrently with the appearance of the cutaneous lesions. With discontinuation of photochemotherapy, the cutaneous lesions disappeared and the pancytopenia improved.
Dowdy
M J
MJ
Section of Rheumatology, Washington Hospital Center, Washington, DC 20010.
Nigra
T P
TP
Barth
W F
WF
D000368:Aged; D000974:Antibodies, Antinuclear / Q000032:analysis; D003176:Complement C3 / Q000032:analysis; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000139:chemically induced* / Q000188:drug therapy / Q000276:immunology; D011701:PUVA Therapy / Q000009:adverse effects*; D011565:Psoriasis / Q000188:drug therapy*
D000974:Antibodies, Antinuclear; D003176:Complement C3; D005938:Glucocorticoids