[Circulating anticellular antibodies in male patients: coincidence of antibodies to intermediate filaments and HLA-B27 in Reiter syndrome].
Evaluating 57 male patients with anticellular antibodies (detected on HEp-2 cells) we could find an association of Reiter's syndrome (17/57), IgG antibodies to intermediate filaments (vimentin type) of the cytoskeleton (17/17) and HLA-B27 (13/17). We conclude, that both, genetic and hormonal factors may influence the humoral immune response in males with Reiter's syndrome. IgG antibodies to intermediate filaments might be precious additional markers for diagnosis of Reiter's syndrome in males.
Haberhauer
G
G
Medizinischen Abteilung mit Rheumatologie, Kaiser-Franz-Josef-Spital der Stadt Wien.
Bröll
H
H
D016918:Arthritis, Reactive / Q000235:genetics / Q000276:immunology*; D001323:Autoantibodies / Q000032:analysis*; D003599:Cytoskeleton / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D006580:Genetic Carrier Screening; D015235:HLA-B Antigens / Q000235:genetics / Q000276:immunology*; D015796:HLA-B27 Antigen; D006801:Humans; D007382:Intermediate Filaments / Q000276:immunology*; D008297:Male; D009130:Muscle, Smooth / Q000276:immunology; D012729:Sex Chromosome Aberrations / Q000235:genetics; D014998:Y Chromosome
D001323:Autoantibodies; D015235:HLA-B Antigens; D015796:HLA-B27 Antigen
Zirkulierende antizelluläre Antikörper bei männlichen Patienten: Koinzidenz von Antikörpern gegen Intermediär-Filamente und HLA-B27 beim Reiter-Syndrom.