title: Use of the isocitrate dehydrogenase structural gene for attachment of e14 in Escherichia coli K-12.
abstract: The e14 element appears to be integrated into the Escherichia coli K-12 isocitrate dehydrogenase structural gene (icd). In being integrated, it replaced the last 52 codons of the gene with a closely related sequence. The two versions of the icd gene produce proteins of the same length but differ by 12 base substitutions that would cause two conservative amino acid replacements.
authors.affiliation: Department of Biological Chemistry, Milton S. Hershey Medical Center, Pennsylvania 17033.
authors.forename: C W
authors.initials: CW
authors.lastname: Hill
authors.forename: J A
authors.initials: JA
authors.lastname: Gray
authors.forename: H
authors.initials: H
authors.lastname: Brody
mesh_terms: D000595:Amino Acid Sequence; D001287:Attachment Sites, Microbiological; D001426:Bacterial Proteins / Q000235:genetics* / Q000302:isolation & purification; D001483:Base Sequence; D004926:Escherichia coli / Q000235:genetics*; D005796:Genes; D005798:Genes, Bacterial; D007521:Isocitrate Dehydrogenase / Q000235:genetics* / Q000302:isolation & purification; D008242:Lysogeny; D008969:Molecular Sequence Data
chemical_list: D001426:Bacterial Proteins; D007521:Isocitrate Dehydrogenase