title: Importance of trigger sensitivity to ventilator response delay in advanced chronic obstructive pulmonary disease with respiratory failure.
abstract: We examined mechanisms of ventilator asynchrony and noncapture in a typical ventilator-dependent patient who failed numerous attempts at weaning. As trigger sensitivity was decreased within its usual range, a marked and progressive ventilator response delay occurred which was associated with erratic changes in functional residual capacity as well as dyspnea and tachypnea. This phenomenon varies among ventilators and underscores the importance of understanding technical differences between them. Appropriate ventilator selection is as important as mode selection when attempting to wean patients with advanced chronic obstructive pulmonary disease.
authors.affiliation: Department of Medicine, University of Southern California School of Medicine, Los Angeles.
authors.forename: M J
authors.initials: MJ
authors.lastname: Gurevitch
authors.forename: D
authors.initials: D
authors.lastname: Gelmont
mesh_terms: D000368:Aged; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000503:physiopathology* / Q000628:therapy; D012119:Respiration; D012131:Respiratory Insufficiency / Q000503:physiopathology* / Q000628:therapy; D015300:Ventilator Weaning