title: Desensitization to aspirin in aspirin-sensitive patients with rhino-sinusitis and asthma: a review.
abstract: Patients with asthma and nasal polyps have been warned to avoid aspirin because of a tendency to develop hypersensitivity reactions. It is now possible to carefully build up a tolerance to aspirin in these patients. This often leads to symptomatic improvement. It also has important implications for those patients who may require aspirin for reasons of cardiovascular disease.
authors.affiliation: Department of Medicine, Sunnybrook Medical Centre, Toronto, Ontario, Canada.
authors.forename: A
authors.initials: A
authors.lastname: Knight
mesh_terms: D001241:Aspirin / Q000009:adverse effects*; D001249:Asthma / Q000150:complications*; D003888:Desensitization, Immunologic; D004342:Drug Hypersensitivity / Q000150:complications / Q000628:therapy*; D006801:Humans; D009298:Nasal Polyps / Q000150:complications; D012220:Rhinitis / Q000150:complications*; D012852:Sinusitis / Q000150:complications*
chemical_list: D001241:Aspirin