[Synthesis of derivative of 2-[4-hydroxy-7-methyl-5-oxo-5H-furo-[3,2g] [1]benzopyran-9-yloxy] acetic and propionic acids with potential effect on the circulatory system].
With the purpose of obtaining new compounds with antiarrhythmic activity, 14 novel derivatives of 5H-furo[3,2-g] [1]benzopyran-5-one were synthetized. Some of them proved to display strong antiarrhythmic action.
Zawadowski
T
T
Turło
J
J
D000085:Acetates / Q000138:chemical synthesis / Q000627:therapeutic use*; D000889:Anti-Arrhythmia Agents; D001145:Arrhythmias, Cardiac / Q000188:drug therapy*; D001578:Benzopyrans / Q000138:chemical synthesis / Q000627:therapeutic use*; D055598:Chemical Phenomena; D002621:Chemistry; D006801:Humans; D011422:Propionates / Q000138:chemical synthesis / Q000627:therapeutic use*
D000085:Acetates; D000889:Anti-Arrhythmia Agents; D001578:Benzopyrans; D011422:Propionates
Synteza pochodnych kwasów 2-[4-hydroksy-7-metylo-5-okso-5h-furo [3,2-g] [1] benzopiran-9-yloksy] octowego i propionowego o spodziewanym działaniu na układ krazenia.