title: A multiple regression analysis for accurate background subtraction in 99Tcm-DTPA renography.
abstract: A technique for accurate background subtraction in 99Tcm-DTPA renography is described. The technique is based on a multiple regression analysis of the renal curves and separate heart and soft tissue curves which together represent background activity. It is compared, in over 100 renograms, with a previously described linear regression technique. Results show that the method provides accurate background subtraction, even in very poorly functioning kidneys, thus enabling relative renal filtration and excretion to be accurately estimated.
authors.affiliation: Department of Medical Physics and Bioengineering, University Hospital of Wales, Cardiff, UK.
authors.forename: G W
authors.initials: GW
authors.lastname: Middleton
authors.forename: W H
authors.initials: WH
authors.lastname: Thomson
authors.forename: I H
authors.initials: IH
authors.lastname: Davies
authors.forename: A
authors.initials: A
authors.lastname: Morgan
mesh_terms: D006801:Humans; D009392:Nephrectomy; D004369:Pentetic Acid; D011866:Radioisotope Renography; D012044:Regression Analysis; D013382:Subtraction Technique; D013667:Technetium
chemical_list: D013667:Technetium; D004369:Pentetic Acid