title: [Cardiotoxicity of local anesthetics: dynamic electrocardiogram study].
abstract: Twenty-two cardiopathic patients (mean age 54.4 +/- 9.9 years) underwent dynamic electrocardiography during tooth extraction under local anesthesia (mepivacaine hydrochloride 2% plus adrenalin 1:200.000). Heart rate (p less than 0.001), systolic and diastolic blood pressure (p less than 0.001) significantly increased during tooth extraction returning to values near to basal level in the recovery period. No patients showed significant changes in ST segment. One patient with chronic atrial fibrillation presented an increase in ventricular rate (180 beats/min) and appearance of premature ventricular beats, spontaneously regressed. In conclusion, in cardiopathic patients dental operations by local anesthesia with vessel constriction it is possible, provided estimated clinical conditions of patients.
authors.forename: S
authors.initials: S
authors.lastname: Rengo
authors.forename: V
authors.initials: V
authors.lastname: Canonico
authors.forename: M
authors.initials: M
authors.lastname: Simeone
authors.forename: L
authors.initials: L
authors.lastname: Fortunato
authors.forename: C
authors.initials: C
authors.lastname: Tedeschi
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects*; D015716:Electrocardiography, Ambulatory; D005260:Female; D006331:Heart Diseases; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D008297:Male; D008619:Mepivacaine / Q000009:adverse effects*; D008875:Middle Aged; D014081:Tooth Extraction; D014662:Vasoconstrictor Agents
chemical_list: D014662:Vasoconstrictor Agents; D008619:Mepivacaine
vernacular_title: Cardioteossicita degli anestetici locali: studio mediante elettrocardiogramma dinamico.