[Comparison of the action of 2 effective analgesics. Experimental study: tramadol versus tilidine/naloxone].
In the present study involving healthy test subjects, tilidin/naloxone (Valoron N; VAL) proved to have an analgesic effect roughly twice as pronounced as that of tramadol (TRA). Moreover, the analgesic effect of VAL showed a significantly more rapid onset than did that of TRA. This finding reflects the difference in rate of action of the active substances. In accordance with these findings, VAL is thus the most powerful analgesic presently available on the German market on simple prescription.
Bromm
B
B
Herrmann
W M
WM
Scharein
E
E
D002986:Clinical Trials as Topic; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use*; D003511:Cyclohexanols / Q000627:therapeutic use*; D004311:Double-Blind Method; D004338:Drug Combinations; D006801:Humans; D009270:Naloxone / Q000627:therapeutic use*; D010146:Pain / Q000188:drug therapy*; D010147:Pain Measurement; D011897:Random Allocation; D013993:Tilidine / Q000627:therapeutic use*; D014147:Tramadol / Q000627:therapeutic use*
D003509:Cyclohexanecarboxylic Acids; D003511:Cyclohexanols; D004338:Drug Combinations; D009270:Naloxone; D014147:Tramadol; D013993:Tilidine
Zwei effektive Analgetika im Wirkungsvergleich. Experimentelle Studie: Tramadol versus Tilidin/Naloxon.