A new small animal inhalation facility: design and performance.
A new inhalation facility is described which allows any combination of up to 72 rodents ranging in size from the mouse to the guinea pig to be exposed simultaneously. Typically for aerosols of MMD 1.5 microns the initial lung deposit in the rat is 0.05 to 0.07% of the total amount of material used and the coefficient of variation between animals is 15 to 20%.
Hodgson
A
A
National Radiological Protection Board, Didcot, Oxon, UK.
Moody
J C
JC
Stradling
G N
GN
Bailey
M R
MR
Stather
J W
JW
D000280:Administration, Inhalation; D000336:Aerosols; D000576:Americium / Q000008:administration & dosage; D000818:Animals; D006168:Guinea Pigs; D051379:Mice; D011005:Plutonium / Q000008:administration & dosage; D012106:Research / Q000295:instrumentation*; D012107:Research Design
D000336:Aerosols; D011005:Plutonium; D000576:Americium