Herpes labialis treatment with acyclovir 5 per cent ointment.
Eighty patients who were culture-confirmed positive for recurrent herpes labialis were entered into a clinical trial. Sixty of these completed two episodes each in a randomized, double-blind, placebo-controlled clinical trial of 5 per cent acyclovir in a polyethylene glycol ointment base. The 5 per cent acyclovir ointment failed to show better clinical healing effects than placebo in both documented episodes. There were no serious side effects observed in either group.
Raborn
G W
GW
McGaw
W T
WT
Grace
M
M
Houle
L
L
D000212:Acyclovir / Q000008:administration & dosage / Q000627:therapeutic use*; D000328:Adult; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006560:Herpes Labialis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009824:Ointments; D010919:Placebos; D011092:Polyethylene Glycols; D011897:Random Allocation; D012008:Recurrence
D009824:Ointments; D010919:Placebos; D011092:Polyethylene Glycols; D000212:Acyclovir