title: [A short course of chemotherapy in newly diagnosed and retreatment of smear-positive pulmonary tuberculosis in a rural area].
abstract: The main purpose of this paper is to investigate the applicability of short course chemotherapy in treating smear-positive tuberculosis in countryside. For the sake of examining compliance with the relevant chemotherapy, 184 newly diagnosed patients treated with 2SHRZ/4HRE regimen, were allocated into two groups, 47 cases in hospital and 137 cases in home treatment with supervision. The sputum conversion rates of the two groups were 100.0% and 96.7% respectively, without any bacteriological relapse in the following 2 years. 115 retreatment smear-positive cases were treated with 2SHRZ/6HRE regimen at home. The sputum conversion rate was 91.5%. The bacteriological relapse rate was 7.6% in 2 years followup. These results unveiled that short-course chemotherapy is practicable in rural area.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination / Q000008:administration & dosage; D006801:Humans; D007538:Isoniazid / Q000008:administration & dosage*; D008875:Middle Aged; D012293:Rifampin / Q000008:administration & dosage*; D012424:Rural Population; D013183:Sputum / Q000382:microbiology; D013307:Streptomycin / Q000008:administration & dosage*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D007538:Isoniazid; D012293:Rifampin; D013307:Streptomycin