title: Ten-year experience with primary ocular 'reticulum cell sarcoma' (large cell non-Hodgkin's lymphoma).
abstract: Fourteen patients with intraocular 'reticulum cell sarcoma' (non-Hodgkin's large cell lymphoma) ranging in age from 27 to 77 are presented. All patients had evidence of vitritis with 50% showing intraretinal and/or subretinal lesions and 21% having anterior uveitis. Five of the patients developed central nervous system lesions and subsequently died. Primary radiation therapy to the eyes and CNS appears to prevent spread of the disease and improve longevity. Chemotherapy improved survival in one patient with CNS spread of disease.
authors.affiliation: Department of Ophthalmology, Mount Sinai School of Medicine, New York, New York 10029.
authors.forename: M J
authors.initials: MJ
authors.lastname: Siegel
authors.forename: J
authors.initials: J
authors.lastname: Dalton
authors.forename: A H
authors.initials: AH
authors.lastname: Friedman
authors.forename: J
authors.initials: J
authors.lastname: Strauchen
authors.forename: C
authors.initials: C
authors.lastname: Watson
mesh_terms: D000328:Adult; D000368:Aged; D002493:Central Nervous System Diseases / Q000473:pathology; D003131:Combined Modality Therapy; D005134:Eye Neoplasms / Q000473:pathology / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000473:pathology