title: Monitoring of physiological parameters during high frequency ventilation (HFV).
abstract: Non-biological descriptors such as jet feeding pressure and oscillator stroke volume are often used to describe HFV. This results in confusion and hinders acceptance of HFV. The goal of this paper is to show how physiological parameters which are valid during HFV can be monitored. Airway pressure measured in narrow tubes with high linear flow rates is underestimated. A relevant airway pressure must be measured well below the tracheal tube. Pressure measured higher up should be validated against peripheral pressure measurements. Minute ventilation and expired CO2 concentration can be determined with a ServoVentilator and a CO2 analyzer arranged at its exit port. Minute ventilation and CO2 elimination can thereby be continuously monitored during high frequency jet ventilation or so-called "combined high frequency jet ventilation" to prevent undetected disturbance of ventilation and perfusion. Physiological dead space can be studied for optimization of ventilatory pattern. The principle of gas analysis at the exit port of the ventilator may be used for FRC determinations with sulfur-hexafluoride.
authors.affiliation: Department of Clinical Physiology, University of Lund, Sweden.
authors.forename: B
authors.initials: B
authors.lastname: Jonson
authors.forename: B
authors.initials: B
authors.lastname: Lachmann
authors.forename: R
authors.initials: R
authors.lastname: Fletcher
mesh_terms: D000818:Animals; D004285:Dogs; D006611:High-Frequency Jet Ventilation; D006612:High-Frequency Ventilation; D006801:Humans; D008991:Monitoring, Physiologic / Q000379:methods*; D013552:Swine