[The anticoagulant and antisclerotic effects of isopropoxygermatrane and methylethyl(silatrane-1-ylmethyl)sulfonium iodide].
In the experiments on rabbits with experimental atherosclerosis the authors revealed lipolytic and antisclerotic effect of the above drug. It was also observed that it also possessed anticoagulation activity.
Rasulov
M M
MM
Kuznetsov
I G
IG
Velikaia
M V
MV
Kaplan
B S
BS
Voronkov
M G
MG
D000818:Animals; D000925:Anticoagulants / Q000494:pharmacology* / Q000627:therapeutic use; D001161:Arteriosclerosis / Q000097:blood / Q000188:drug therapy; D001777:Blood Coagulation / Q000187:drug effects; D001643:Bridged Bicyclo Compounds / Q000494:pharmacology* / Q000627:therapeutic use; D019086:Bridged Bicyclo Compounds, Heterocyclic; D001952:Bridged-Ring Compounds / Q000494:pharmacology*; D004353:Drug Evaluation, Preclinical; D066298:In Vitro Techniques; D008055:Lipids / Q000097:blood; D009570:Nitriles / Q000494:pharmacology* / Q000627:therapeutic use; D009861:Onium Compounds / Q000494:pharmacology*; D009942:Organometallic Compounds / Q000494:pharmacology* / Q000627:therapeutic use; D011817:Rabbits; D012825:Silicon / Q000494:pharmacology* / Q000627:therapeutic use; D013452:Sulfonium Compounds / Q000494:pharmacology* / Q000627:therapeutic use; D013997:Time Factors
D000925:Anticoagulants; D001643:Bridged Bicyclo Compounds; D019086:Bridged Bicyclo Compounds, Heterocyclic; D001952:Bridged-Ring Compounds; D008055:Lipids; D009570:Nitriles; D009861:Onium Compounds; D009942:Organometallic Compounds; D013452:Sulfonium Compounds; C060353:isopropoxygermatrane; C058763:methylethyl(silatrane-1-ylmethyl)sulfonium; D012825:Silicon
Antikoaguliantnye i antiskleroticheskie éffekty izopropoksigermatrana i metilétil (silatran-1-ilmetil[sul'foniĭ ĭodida.