Modifying action of gamma-radiation in mutagenesis of E. coli WU36-10 induced by ethylene oxide, ethyl methanesulfonate and methyl methanesulfonate.
The influence of gamma-radiation pre-exposure on ethylene oxide, ethyl methanesulfonate and methyl methanesulfonate mutagenesis in Escherichia coli WU36-10 was studied. Pretreatment with gamma-radiation resulted, in the case of subsequent treatment with ethylene oxide and ethyl methanesulfonate, in a decrease of the frequency of leu+ revertants, and in the case of subsequent treatment with methyl methanesulfonate, in an increase of this mutation frequency.
Kolman
A
A
Department of Radiobiology, University of Stockholm, Sweden.
Näslund
M
M
Granath
F
F
D004260:DNA Repair / Q000528:radiation effects*; D004926:Escherichia coli / Q000187:drug effects / Q000528:radiation effects; D005020:Ethyl Methanesulfonate / Q000633:toxicity*; D005027:Ethylene Oxide / Q000633:toxicity*; D005720:Gamma Rays; D008741:Methyl Methanesulfonate / Q000633:toxicity*; D009154:Mutation / Q000187:drug effects* / Q000528:radiation effects*; D013223:Statistics as Topic
D005020:Ethyl Methanesulfonate; D008741:Methyl Methanesulfonate; D005027:Ethylene Oxide