title: Chromosomal mapping and gene disruption of the ADHIII gene in aspergillus nidulans.
abstract: There are at least three alcohol dehydrogenases in Aspergillus nidulans. ADHIII has no obvious physiological function. We describe here the cloning of the ADHIII gene (alcC), its mapping on linkage group VII by "reverse genetics", and the properties of multicopy transformants tested for their ability to grow on a range of alcohols (butan-1-ol being the best substrate tested for growth). We were unable to detect any obvious alteration in phenotype of a strain carrying a disrupted copy of the ADHIII gene.
authors.affiliation: Department of Biochemistry, University of Hull, UK.
authors.forename: I G
authors.initials: IG
authors.lastname: Jones
authors.forename: H M
authors.initials: HM
authors.lastname: Sealy-Lewis
mesh_terms: D000426:Alcohol Dehydrogenase / Q000235:genetics*; D001233:Aspergillus nidulans / Q000201:enzymology / Q000235:genetics* / Q000254:growth & development; D015152:Blotting, Northern; D015139:Blotting, Southern; D002874:Chromosome Mapping; D005796:Genes; D005800:Genes, Fungal; D008040:Genetic Linkage; D007527:Isoenzymes / Q000235:genetics*; D010957:Plasmids; D015183:Restriction Mapping; D014170:Transformation, Genetic
chemical_list: D007527:Isoenzymes; D000426:Alcohol Dehydrogenase