title: Update on NSAIDS in the elderly.
abstract: Nonsteroidal anti-inflammatory drugs (NSAIDs) can effectively reduce pain and inflammation. Although these agents are potent inhibitors of prostaglandin synthesis, they probably have other effects on the inflammatory process. NSAIDs produce a number of side effects, particularly in elderly patients. Understanding the effects of aging on drug pharmacokinetics will help minimize these complications.
authors.affiliation: University of California, San Francisco.
authors.forename: K E
authors.initials: KE
authors.lastname: Sack
mesh_terms: D000368:Aged; D000375:Aging; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000493:pharmacokinetics; D006801:Humans; D012459:Salicylates / Q000009:adverse effects / Q000493:pharmacokinetics
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D012459:Salicylates