Association of Candida with carcinoma of esophagus.
Twenty-five patients with carcinoma of the esophagus (group I) and 25 patients suffering from non-ulcer dyspepsia with normal endoscopy (group II) were studied to know the incidence of isolation of Candida from their esophagus. Endoscopic brushings were taken from the esophagus in both groups and studied by smear examination and culture. Fungal organisms could be detected in 75% of cases of group I and 32% of cases of group II by culture techniques, and 45.8% and 12% respectively by smear examination. The difference was statistically significant (p less than 0.05) for both the techniques. Candida albicans was the commonest species isolated. No correlation was found between Candida agglutination titres and density of Candida growth on culture. We conclude that an association exists between carcinoma esophagus and the occurrence of Candida in the esophagus.
Bhatia
V
V
Kochhar
R
R
Talwar
P
P
Gupta
N M
NM
Mehta
S K
SK
D002176:Candida albicans / Q000302:isolation & purification; D002177:Candidiasis / Q000175:diagnosis*; D002294:Carcinoma, Squamous Cell / Q000382:microbiology*; D004415:Dyspepsia / Q000382:microbiology*; D004938:Esophageal Neoplasms / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged