Epilepsy and brain tumours in children.
Although epilepsy is one of the clinical manifestations of brain tumour in one out of three children, such tumours are only found in 1 to 2% of epileptic children explored. When epilepsy reveals the tumour, the latter is benign in 9 out of 10 cases: usually an astrocytoma, an oligodendroglioma or a mixed oligoastrocytic tumour. These tumours accounted for 84% of benign tumours of the cerebral hemispheres among children treated by surgery in our department at the Enfants Malades hospital, Paris; 76% of them had been revealed by epileptic seizures. Among other lesions responsible for epilepsy were 2 cavernous angiomas and 6 thrombotic angiomas. Brain tumours were located in the temporal lobe in almost one half of the cases. The type of epileptic attack was variable, but complex partial seizures were the majority (47%). Several types were associated in 30% of the cases. Surgery was the only treatment in view of the very low recurrence rate. In 80% of the case, removal of the tumour was sufficient to suppress epilepsy. 71% of the children operated upon have an IQ of more than 80; 77% have normal schooling.
Hirsch
J F
JF
D000293:Adolescent; D001254:Astrocytoma / Q000150:complications / Q000601:surgery; D001932:Brain Neoplasms / Q000150:complications* / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004827:Epilepsy / Q000209:etiology* / Q000601:surgery; D004833:Epilepsy, Temporal Lobe / Q000209:etiology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009837:Oligodendroglioma / Q000150:complications / Q000601:surgery; D011183:Postoperative Complications; D013702:Temporal Lobe / Q000473:pathology