Preliminary results on clinical and immunological effects of thymus hormone preparations in AIDS.
The human immunodeficiency virus (HIV) is the newly recognized agent of the acquired immunodeficiency syndrome (AIDS). Global defects of the immune functions, including T- and B-cell immunity, macrophage functions and cytokine production, are commonly observed among patients with HIV infection. Many studies have shown thymus involvement and endocrine function impairments among these patients. Clinical trials with thymic compounds aiming at restoring the immune dysfunctions will be reviewed.
Hermans
P
P
Division of Infectious Diseases, St Pierre University Hospital, Brussels, Belgium.
Clumeck
N
N
D000163:Acquired Immunodeficiency Syndrome / Q000628:therapy*; D006801:Humans; D013951:Thymus Hormones / Q000627:therapeutic use*
D013951:Thymus Hormones