Hypokalaemic, hypophosphatemic thyrotoxic periodic paralysis.
Thyrotoxic periodic paralysis is an uncommon neuromuscular disorder frequently associated with severe hypokalemia. We describe a patient with hypophosphatemia occurring in the setting of hypokalemic thyrotoxic periodic paralysis, an association reported only once previously. A review of the literature indicates that this combined biochemical derangement may not be uncommon and that thyrotoxic periodic paralysis should be recognized as a potential cause of hypophosphatemia. The correction of both hypokalemia and hypophosphatemia may lead to a more rapid resolution of the associated acute neurologic syndrome.
Nora
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St Francis Hospital, Evanston, IL 60202.
Berns
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AS
D000328:Adult; D006111:Graves Disease / Q000150:complications*; D006630:Hispanic or Latino; D006801:Humans; D007008:Hypokalemia / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008800:Mexico / Q000208:ethnology; D009468:Neuromuscular Diseases / Q000209:etiology / Q000628:therapy; D010245:Paralyses, Familial Periodic / Q000209:etiology*; D010710:Phosphates / Q000097:blood* / Q000627:therapeutic use; D011188:Potassium / Q000627:therapeutic use; D017680:Potassium Compounds
D010710:Phosphates; D017680:Potassium Compounds; C013216:potassium phosphate; D011188:Potassium