title: [Infection by Clonorchis sinensis in Asian immigrants in Brazil. Treatment with praziquantel].
abstract: Fifteen adult patients with assymptomatic infection due to Clonorchis sinensis, diagnosed by coprological examination, were studied. They all came from Asia (twelve from Taiwan, two from South Korea and one from Hong Kong) and were examined at the Adolfo Lutz Institute and the Department of Infectious Diseases, School of Medicine, University of São Paulo, in São Paulo, Brazil. Six patients were women and nine men. All studied patients were admitted to hospital and treated with praziquantel (60 mg/kg). Previous to treatment and on the 15th, 30th and 60th days after praziquantel administration, patients were submitted to quantitative stool examinations, according to Kato-Katz's technique and to hematological and biochemical serum analysis. After a 60 day follow-up nine patients (60%) were negative for C. sinensis eggs in stools. Those not cured after praziquantel administration (six patients, 40%) revealed a sharp decline in faecal elimination of C. sinensis eggs.
authors.forename: O H
authors.initials: OH
authors.lastname: Leite
authors.forename: Y
authors.initials: Y
authors.lastname: Higaki
authors.forename: S L
authors.initials: SL
authors.lastname: Serpentini
authors.forename: S A
authors.initials: SA
authors.lastname: Carvalho
authors.forename: V
authors.initials: V
authors.lastname: Amato Neto
authors.forename: D M
authors.initials: DM
authors.lastname: Torres
authors.forename: R M
authors.initials: RM
authors.lastname: Dias
authors.forename: P P
authors.initials: PP
authors.lastname: Chieffi
mesh_terms: D000328:Adult; D000368:Aged; D001938:Brazil; D003003:Clonorchiasis / Q000188:drug therapy* / Q000208:ethnology / Q000469:parasitology; D005202:Asia, Eastern / Q000208:ethnology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010270:Parasite Egg Count / Q000379:methods; D011223:Praziquantel / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D011223:Praziquantel
vernacular_title: Infecção por Clonorchis sinensis em imigrantes asiáticos no Brasil. Tratamento com praziquantel.