[Chronic hepatitis caused by B virus and glomerulonephritis in children].
Eight children with chronic HBV hepatitis and glomerular disease were studied. There were seven males and one female, with ages between one and nine years old. Three had CPH and five CAH. All patients with CPH had membranous nephropathy, and those with CAH three had MNG. one membranoproliferative glomerulonephritis and one mesangial glomerulonephritis. Only six patients had moderate liver enlargement. In all, the diagnosis of HBV infection was performed by investigation of the etiology of their nephropathy. Liver function test showed signs of moderate necrobiosis with impaired biliary acid metabolism. All were HBsAg (+), antiHBc (+), six were antiHBe (+) and two were HBeAg (+). In one case renal deposit of HBsAg was found. Due to the frequent association of HBsAg and glomerulonephritis (GN) in children, an investigation of liver function is highly recommended in those patients with GN a HBV infection.
Jara Vega
P
P
Unidad de Gastroenterología, Hospital Infantil La Paz, Madrid.
Camarena Grande
C
C
Díaz Fernández
M C
MC
Guerra Aguirre
M E
ME
de la Vega Bueno
A
A
Hierro Llanillo
L
L
Rodríguez Sánchez
C
C
Navarro Torres
M
M
Vázquez González
C
C
D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D005921:Glomerulonephritis / Q000097:blood / Q000209:etiology*; D006509:Hepatitis B / Q000097:blood / Q000150:complications*; D006511:Hepatitis B Antigens / Q000032:analysis; D006801:Humans; D007223:Infant; D008111:Liver Function Tests; D008297:Male
D006511:Hepatitis B Antigens
Hepatitis crónica por virus B y glomerulonefritis en niños.