title: Determination of benzene, toluene and 1,3-butadiene in cigarette smoke by GC-MDS.
abstract: An analytical procedure was devised for the determination of selected gas phase constituents in cigarette smoke utilizing capillary gas chromatography and mass selective detection (GC-MSD); the MSD was used in the selective ion monitoring mode (SIM). The gas of freshly generated mainstream smoke was analyzed via a 10-port gas sampling valve on a puff-by-puff basis. Benzene, toluene, and 1,3-butadiene were found in the range of 6-73, 5-88, and 16-75 micrograms/cigarette, respectively. The gas phase of sidestream smoke was trapped in methanol using 3 midget impingers at -78 degrees C. Benzene in sidestream smoke was found in the range of 490-840 micrograms/cigarette; toluene and 1,3-butadiene levels were 1,090-1,690 and 300-470 micrograms/cigarette, respectively. Environmental tobacco smoke (ETS), sampled in a smoke-filled bar, was analyzed using the cold trap method. The concentrations of benzene and toluene in this indoor air were found to be 26-36 and 41-80 micrograms/m3, respectively, while 1,3-butadiene was present at 3.3-4.5 micrograms/m3.
authors.affiliation: American Health Foundation, Valhalla, NY 10595.
authors.forename: K D
authors.initials: KD
authors.lastname: Brunnemann
authors.forename: M R
authors.initials: MR
authors.lastname: Kagan
authors.forename: J E
authors.initials: JE
authors.lastname: Cox
authors.forename: D
authors.initials: D
authors.lastname: Hoffmann
mesh_terms: D001554:Benzene / Q000032:analysis*; D002070:Butadienes / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D009153:Mutagens / Q000032:analysis*; D012906:Smoke / Q000032:analysis*; D014028:Tobacco Smoke Pollution / Q000032:analysis*; D014050:Toluene / Q000032:analysis*
chemical_list: D002070:Butadienes; D009153:Mutagens; D012906:Smoke; D014028:Tobacco Smoke Pollution; D014050:Toluene; D001554:Benzene; C031763:1,3-butadiene