Primary sclerosing cholangitis in India.
Six patients with PSC have been diagnosed and followed up at a centre in Northern India for periods up to 4 years. They all presented with cholestatic jaundice and cholangitis, but one of them subsequently presented with variceal haemorrhage. Cholangiographic features were the most characteristic and included irregular narrowing and segmental dilatation of the biliary radicles giving them a beaded appearance. Treating them was most frustrating. Two of them died of hepatic encephalopathy, others have also continued to be sick during the follow-up.
Acharya
S K
SK
Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi.
Vashisht
S
S
Tandon
R K
RK
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D002758:Cholangiography; D015209:Cholangitis, Sclerosing / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D002780:Cholestasis, Intrahepatic / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D002792:Cholestyramine Resin / Q000627:therapeutic use; D003093:Colitis, Ulcerative / Q000150:complications*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007194:India; D008297:Male; D008875:Middle Aged; D014463:Ultrasonography
D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D002792:Cholestyramine Resin