The peripheral circulation.
In severe congestive heart failure, exercise capacity is reduced. This is not directly due to reduced ventricular function. We present evidence in this article that peripheral vascular abnormalities are important in determining exercise capacity. We believe the vascular abnormalities noted in heart failure may be related to both sodium retention and deconditioning. Moreover, we propose that in severe heart failure this vascular response may be protective.
Sinoway
L I
LI
Division of Cardiology, Pennsylvania State University, Milton S. Hershey Medical Center, Hershey.
Zelis
R
R
D001775:Blood Circulation; D001794:Blood Pressure; D015444:Exercise; D006333:Heart Failure / Q000097:blood / Q000503:physiopathology*; D006801:Humans; D009132:Muscles / Q000098:blood supply*