title: Chromosome aberrations and dominant lethals in Culex fatigans due to mercuric chloride.
abstract: The mosquito, Culex fatigans, was used for determining the possible mutagenic potential of mercuric chloride, using chromosome aberrations and frequency of dominant lethals as the parameters. As many as 27.75 +/- 0.85% aberrations against 2.75 +/- 0.35% (P less than 0.001) in the controls were observed in the chromosomes of the animals treated with 0.001 microgram/ml of mercuric chloride. Similarly the frequency of dominant lethals was statistically significant in the treated lot. The results indicate that this compound is genotoxic.
authors.affiliation: Department of Zoology, Panjab University, Chandigarh, India.
authors.forename: G P
authors.initials: GP
authors.lastname: Sharma
authors.forename: R C
authors.initials: RC
authors.lastname: Sobti
authors.forename: A
authors.initials: A
authors.lastname: Chaudhry
authors.forename: K K
authors.initials: KK
authors.lastname: Ahluwalia
mesh_terms: D000818:Animals; D002869:Chromosome Aberrations; D003465:Culex / Q000187:drug effects / Q000235:genetics*; D008627:Mercuric Chloride / Q000633:toxicity*; D009153:Mutagens / Q000633:toxicity*
chemical_list: D009153:Mutagens; D008627:Mercuric Chloride