title: [A case of advanced paratesticular rhabdomyosarcoma].
abstract: A case of paratesticular rhabdomyosarcoma is presented. An 18-year-old male was admitted with the complaint of giant scrotal swelling and abdominal fullness on September 5, 1986. Left radical orchiectomy was performed with the pathologic diagnosis of alveolar rhabdomyosarcoma. The tumor was paratesticular in location and had invaded a spermatic cord. Radiological examination showed a gross metastatic mass in retroperitoneal lymph nodes, supraclavicular lymph nodes and Douglas pouch. The patient received induction chemotherapy containing vincristine, actinomycin-D, cyclophosphamide, bleomycin, CDDP and VP-16. After 3 courses, he had no mass in Douglas pouch and supraclavicular lesion. He received retroperitoneal lymph node dissection for residual retroperitoneal mass, and postoperative radiotherapy was given. However, recurrent disease was developed in the paraaortic region with malignant ascites. He was treated with salvage chemotherapy, had without any significant effect. He died of liver dysfunction due to progressive mass in hepatic hilum. A review of the current approach of paratesticular rhabdomyosarcoma with the usefulness of combination chemotherapy is given.
authors.affiliation: Department of Urology, Wakayama Red Cross Hospital.
authors.forename: M
authors.initials: M
authors.lastname: Hiura
authors.forename: J
authors.initials: J
authors.lastname: Takenawa
authors.forename: O
authors.initials: O
authors.lastname: Ryoji
authors.forename: Y
authors.initials: Y
authors.lastname: Taki
authors.forename: T
authors.initials: T
authors.lastname: Hayashi
authors.forename: T
authors.initials: T
authors.lastname: Kiriyama
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D005834:Genital Neoplasms, Male / Q000188:drug therapy*; D006801:Humans; D008297:Male; D012208:Rhabdomyosarcoma / Q000188:drug therapy*; D012611:Scrotum; D013737:Testis