title: Mechanisms leading to toxin-induced impairment of renal function, with a focus on immunopathology.
abstract: Environmental, occupational and therapeutic exposure to nephrotoxic compounds may cause different forms of renal disease and constitutes a major health problem. This paper discusses pathogenetic mechanisms leading to impairment of renal function and early detection of its symptoms, with special emphasis on immunopathology. Finally, it focuses on ways of identifying potentially nephrotoxic compounds.
authors.affiliation: Department of Pathology, State University of Groningen, The Netherlands.
authors.forename: J J
authors.initials: JJ
authors.lastname: Weening
mesh_terms: D001327:Autoimmune Diseases / Q000139:chemically induced* / Q000503:physiopathology; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced* / Q000276:immunology / Q000503:physiopathology; D007678:Kidney Glomerulus / Q000503:physiopathology; D007684:Kidney Tubules / Q000503:physiopathology