title: Malignant lymphoma of the testis: histological and immunohistological study of 28 cases.
abstract: Histological and immunohistological studies were made in 28 patients with testicular lymphoma who presented with a right (15), left (11) or bilateral (2) scrotal swelling. Patient age at hospitalization ranged from 39 to 87 years, with a median age of 64 years. The disease was stage 1 in 12 patients, stage 2 in 11 and stage 3 in 5. Histologically, most of the neoplasms were of the diffuse large cell type, with an immunoblastic type being the most common. Immunohistochemistry revealed that all but 2 cases were of the B cell type. None of the tumors reacted with monoclonal antibody for T cell. These findings suggested that testicular lymphoma exclusively consisted of the B cell type, identical to previous reports of extranodal lymphomas other than those in the skin. The pertinent literature is reviewed and the histogenesis of testicular lymphoma is discussed.
authors.affiliation: Department of Pathology, Osaka University Medical School, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Nonomura
authors.forename: K
authors.initials: K
authors.lastname: Aozasa
authors.forename: T
authors.initials: T
authors.lastname: Ueda
authors.forename: A
authors.initials: A
authors.lastname: Okuyama
authors.forename: M
authors.initials: M
authors.lastname: Matsuda
authors.forename: S
authors.initials: S
authors.lastname: Hida
authors.forename: O
authors.initials: O
authors.lastname: Yoshida
authors.forename: Y
authors.initials: Y
authors.lastname: Kobashi
authors.forename: N
authors.initials: N
authors.lastname: Shima
authors.forename: H
authors.initials: H
authors.lastname: Yamabe
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000911:Antibodies, Monoclonal; D006801:Humans; D007124:Immunoenzyme Techniques; D008228:Lymphoma, Non-Hodgkin / Q000401:mortality / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D013736:Testicular Neoplasms / Q000401:mortality / Q000473:pathology*; D013737:Testis / Q000473:pathology*
chemical_list: D000911:Antibodies, Monoclonal