title: Dexamethasone in the treatment of bronchopulmonary dysplasia.
abstract: Sixteen chronically ventilator-dependent newborns with BPD were treated with one or more cycles of dexamethasone (0.5 mg/kg/day). In 11 cases extubation was possible during the therapy period. Ventilatory parameters were lowered in 3 other newborns. FIO2, respiratory rate, PIP, and PEEP, assessed before and after dexamethasone administration, decreased in a statistically significant way. Our data confirm the utility of dexamethasone in the extubation in chronically ventilated infants with BPD.
authors.affiliation: Department of Paediatrics, University of Padova, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Benini
authors.forename: F F
authors.initials: FF
authors.lastname: Rubaltelli
authors.forename: P
authors.initials: P
authors.lastname: Griffith
authors.forename: M
authors.initials: M
authors.lastname: Sala
authors.forename: C
authors.initials: C
authors.lastname: Zorzi
mesh_terms: D001997:Bronchopulmonary Dysplasia / Q000188:drug therapy* / Q000503:physiopathology / Q000628:therapy; D003907:Dexamethasone / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D007902:Length of Stay; D010102:Oxygen Inhalation Therapy; D012121:Respiration, Artificial; D012129:Respiratory Function Tests
chemical_list: D003907:Dexamethasone