Influence of external administration of epinephrine on bone regeneration.
The effect of local administration of epinephrine was tested in a rabbit experimental model. Identical commercially pure titanium implants were inserted in the right legs of New Zealand white rabbits after pretreatment with epinephrine; the left legs served as controls. This acute administration of epinephrine was shown to have no significant impact on the incorporation of the implant as measured after 7 weeks.
Bolind
P
P
Wennerberg
A
A
Albrektsson
T
T
D000818:Animals; D001861:Bone Regeneration / Q000187:drug effects*; D015921:Dental Implants; D004837:Epinephrine / Q000008:administration & dosage*; D006487:Hemostasis / Q000187:drug effects; D008954:Models, Biological; D011817:Rabbits; D013314:Stress, Mechanical; D014025:Titanium
D015921:Dental Implants; D014025:Titanium; D004837:Epinephrine