title: Second neoplasms in Hodgkin's disease: current controversies.
abstract: Aggressive, multimodal treatment of Hodgkin's disease has led to dramatic increases in survival but not without significant early toxicity and late complications. The most serious late complication is the development of a secondary neoplasm. These secondary cancers include acute nonlymphocytic leukemia, non-Hodgkin's lymphoma, and various solid tumors.
authors.affiliation: Department of Medicine, Veterans Administration Medical Center, Northport, New York.
authors.forename: M H
authors.initials: MH
authors.lastname: Zarrabi
authors.forename: F
authors.initials: F
authors.lastname: Rosner
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy / Q000009:adverse effects; D005260:Female; D006689:Hodgkin Disease / Q000628:therapy*; D006801:Humans; D007223:Infant; D007558:Italy; D007938:Leukemia / Q000139:chemically induced / Q000453:epidemiology; D007953:Leukemia, Radiation-Induced / Q000209:etiology; D008228:Lymphoma, Non-Hodgkin / Q000139:chemically induced / Q000453:epidemiology / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000139:chemically induced / Q000453:epidemiology; D009378:Neoplasms, Multiple Primary / Q000139:chemically induced / Q000453:epidemiology / Q000209:etiology*; D009381:Neoplasms, Radiation-Induced / Q000209:etiology; D011878:Radiotherapy / Q000009:adverse effects*; D014481:United States