title: [The importance of calcium for secretion in excitable and non-excitable cells].
abstract: Secretion via exocytosis is a process common to excitable as well as non-excitable cells. The notion that this process is entirely determined by a rise in [Ca]i is no longer tenable in view of recent reports demonstrating secretion at basal or even reduced levels of [Ca]i. It appears appropriate to distinguish between electrically excitable and electrically non-excitable cells. In the former, a rise in [Ca]i is the triggering event for secretion, whereas in the latter, second messengers seem to induce secretion while [Ca]i acts as a modulator of the rate of secretion. Conversely, second messengers may modulate Ca-induced secretion in excitable cells.
authors.affiliation: Max-Planck-Institut für Biophysikalische Chemie, Göttingen.
authors.forename: R
authors.initials: R
authors.lastname: Penner
authors.forename: E
authors.initials: E
authors.lastname: Neher
mesh_terms: D000818:Animals; D002118:Calcium / Q000502:physiology*; D005088:Exocrine Glands / Q000166:cytology / Q000378:metabolism*; D006801:Humans
chemical_list: D002118:Calcium
vernacular_title: Die Bedeutung des Calciums für die Sekretion in erregbaren und nicht-erregbaren Zellen.