[A thioridazine-dihydroergotoxine combination in the treatment of senile pruritus].
Senile itching, a peculiar clinical situation consisting of a cutaneous senile involution associated with a relevant neurogenic component, still keeps being a difficult therapeutic problem. For the purpose, a clinical trial, carried out with a combination of thioridazine and dihydroergotoxine on 19 patients carriers of the affection, could show a relevant decrease in all parameters assessed, ie itching, muscle tension and skin temperature measured by biofeedback. The combination also showed a good tolerance.
Polenghi
M
M
Colombo
M D
MD
Barcella
M L
ML
Perego
M
M
D000284:Administration, Oral; D000818:Animals; D001007:Anxiety; D002415:Cats; D003863:Depression; D004088:Dihydroergotoxine / Q000008:administration & dosage / Q000627:therapeutic use*; D004338:Drug Combinations; D004341:Drug Evaluation; D006801:Humans; D008297:Male; D008875:Middle Aged; D011537:Pruritus / Q000188:drug therapy* / Q000523:psychology; D012881:Skin Temperature / Q000187:drug effects; D013881:Thioridazine / Q000008:administration & dosage / Q000627:therapeutic use*
D004338:Drug Combinations; D004088:Dihydroergotoxine; D013881:Thioridazine
Associazione tioridazina-diidroergotossina nel trattamento del prurito senile.