title: Erythropoietic activity in culture media conditioned by rat mesangial cells.
abstract: Using a tissue culture technique we examined erythropoietin (EPO) producing cells in rat glomeruli. In 5 out of 6 independent glomerular cell cultures, EPO activity was found in the mesangial-cell proliferating phase, but not in the epithelial-cell proliferating phase. Therefore, mesangial cells seemed to be EPO producing cells.
authors.affiliation: Third Department of Internal Medicine, Akita University School of Medicine.
authors.forename: Y
authors.initials: Y
authors.lastname: Fukushima
authors.forename: M
authors.initials: M
authors.lastname: Yanagisawa
authors.forename: T
authors.initials: T
authors.lastname: Yasuda
authors.forename: Y
authors.initials: Y
authors.lastname: Nakamoto
authors.forename: A B
authors.initials: AB
authors.lastname: Miura
mesh_terms: D000818:Animals; D003470:Culture Media / Q000032:analysis*; D004921:Erythropoietin / Q000032:analysis / Q000378:metabolism*; D005455:Fluorescent Antibody Technique; D005920:Glomerular Mesangium / Q000378:metabolism* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D003470:Culture Media; D004921:Erythropoietin