title: Clinical evaluation of ketotifen for chronic urticaria: multicenter double-blind comparative study with clemastine.
abstract: A double-blind study was performed in 305 patients to compare ketotifen capsule and clemastine tablet. Ketotifen alleviated eruption and itching to a significantly greater extent than clemastine. The utility rating of ketotifen was significantly higher than that of clemastine.
authors.affiliation: Department of Dermatology, Jikei University, School of Medicine, Tokyo, Japan.
authors.forename: R
authors.initials: R
authors.lastname: Kamide
authors.forename: M
authors.initials: M
authors.lastname: Niimura
authors.forename: H
authors.initials: H
authors.lastname: Ueda
authors.forename: S
authors.initials: S
authors.lastname: Imamura
authors.forename: S
authors.initials: S
authors.lastname: Yamamoto
authors.forename: H
authors.initials: H
authors.lastname: Yoshida
authors.forename: A
authors.initials: A
authors.lastname: Kukita
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002908:Chronic Disease; D002974:Clemastine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007665:Ketotifen / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011759:Pyrrolidines / Q000627:therapeutic use*; D014581:Urticaria / Q000188:drug therapy*
chemical_list: D011759:Pyrrolidines; D002974:Clemastine; D007665:Ketotifen