[The role of elastolytic enzymes and smoking in the pathogenesis of emphysema].
Author provides a survey on the incidence rate of emphysema and of its social and economic consequences as well as available experimental data. Discussing her own results the significance of endogenous enzymes, smoking and of factors maintaining protease/antiprotease equilibrium are mentioned. The prophylactive and therapeutic potentials of currently experimental agents are evaluated.
Szemenyei
K
K
D000818:Animals; D004547:Elastic Tissue / Q000648:ultrastructure; D008168:Lung / Q000201:enzymology* / Q000648:ultrastructure; D010196:Pancreatic Elastase / Q000378:metabolism*; D010447:Peptide Hydrolases / Q000378:metabolism; D011656:Pulmonary Emphysema / Q000201:enzymology* / Q000209:etiology; D051381:Rats; D011919:Rats, Inbred Strains; D012907:Smoking / Q000009:adverse effects*
D010447:Peptide Hydrolases; D010196:Pancreatic Elastase
Az elasztolitikus enzimek és a dohányzás szerepe az emphysema patogenezisében.