title: Pregnancies in septate uteri: outcome in relation to site of uterine implantation as determined by sonography.
abstract: Sonography was used to study the site of uterine implantation of 12 pregnancies in eight patients with complete septation of the uterus. The purpose was to determine the incidence of septal implantation in these patients and its relation to the outcome of the pregnancies. The live-birth rate in the 12 pregnancies was 33%. Three pregnancies (25%) went to term and ended in live neonates. One (8%) resulted in a premature delivery and the neonate survived. Eight (67%) ended in abortion. Sonograms showed that in all four pregnancies that were not aborted, implantation was in the lateral wall of the uterus. In comparison, in the eight pregnancies that terminated in abortion, implantation was septal in six, mixed in one, and undetermined in one. Our experience with this small group of patients suggests that pregnancies in septate uteri have a poor prognosis and that abortion is related to septal implantation.
authors.affiliation: Clinica Ostetrico-Ginecologica I, Università di Milano, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Fedele
authors.forename: M
authors.initials: M
authors.lastname: Dorta
authors.forename: D
authors.initials: D
authors.lastname: Brioschi
authors.forename: M N
authors.initials: MN
authors.lastname: Giudici
authors.forename: G B
authors.initials: GB
authors.lastname: Candiani
mesh_terms: D000328:Adult; D010064:Embryo Implantation; D005260:Female; D006801:Humans; D009095:Mullerian Ducts; D011247:Pregnancy; D011256:Pregnancy Outcome; D011379:Prognosis; D014463:Ultrasonography; D014599:Uterus / Q000002:abnormalities*