[Immunologic diagnosis of the cerebrospinal fluid and serum in developing brain cysticercosis].
ELISA detection of specific antibodies in the serum (IgG) and cerebrospinal fluid (IgG, IgM and IgA) was evaluated in 28 patients. Diagnosis of cerebral cysticercosis and evaluation of disease activity was based on CT scan findings. Specific IgG antibodies were found in the serum in 83.3% of patients with active disease and 10% of those with inactive disease. Cerebrospinal fluid tests evidenced specific antibodies in all patients with active disease and none of the patients with inactive disease. The specific CSF antibodies were IgG (94.4%), IgM (66.6%) or IgA (66.6%). Antibody titers were significantly higher in patients with an intraventricular vesicle or cyst.
Michault
A
A
Service de Bactériologie-Parasitologie, Hôpital de Saint-Pierre de la Réunion, Centre Hospitalier Général de Saint-Pierre-Le-Tampon.
Leroy
D
D
Coubes
P
P
Laporte
J P
JP
Bertil
G
G
Mignard
C
C
D000293:Adolescent; D000328:Adult; D001927:Brain Diseases / Q000097:blood / Q000134:cerebrospinal fluid / Q000150:complications / Q000175:diagnosis; D002648:Child; D003551:Cysticercosis / Q000097:blood / Q000134:cerebrospinal fluid / Q000150:complications / Q000175:diagnosis*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000134:cerebrospinal fluid*; D007074:Immunoglobulin G / Q000032:analysis* / Q000134:cerebrospinal fluid; D007075:Immunoglobulin M / Q000134:cerebrospinal fluid*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M
Diagnostic immunologique dans le liquide céphalo-rachidien et le sérum de la cysticercose encéphalique évolutive.