title: N-terminal region of Proteus mirabilis glutathione transferase is not homologous to mammalian and plant glutathione transferases.
abstract: The N-terminal amino acid sequence of glutathione transferase, Pm-GST-6.0, purified from Proteus mirabilis [(1988) Biochem. J. 255, 971-975] up to residue 38 and a comparative peptide fingerprint are reported. No obvious homology with the sequences of alpha, pi and mu classes of mammalian glutathione transferases as well as with those of plant glutathione transferases has been noted. These results suggest that the classification so far adopted for glutathione transferases cannot be extended to the bacterial enzyme.
authors.affiliation: Istituto di Scienze Biochimiche, Cattedra di Microbiologia, Università di Chieti, Roma, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Di Ilio
authors.forename: A
authors.initials: A
authors.lastname: Aceto
authors.forename: R
authors.initials: R
authors.lastname: Piccolomini
authors.forename: N
authors.initials: N
authors.lastname: Allocati
authors.forename: A M
authors.initials: AM
authors.lastname: Caccuri
authors.forename: D
authors.initials: D
authors.lastname: Barra
authors.forename: G
authors.initials: G
authors.lastname: Federici
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D005982:Glutathione Transferase / Q000235:genetics*; D008322:Mammals / Q000378:metabolism*; D008969:Molecular Sequence Data; D010944:Plants / Q000201:enzymology* / Q000235:genetics; D011513:Proteus mirabilis / Q000201:enzymology* / Q000235:genetics; D013045:Species Specificity
chemical_list: D005982:Glutathione Transferase