Crystal-associated rheumatic disease. Current management considerations.
Safe, effective treatment is available for acute crystal-associated arthropathy. It is time for some older remedies, phenylbutazone and perhaps colchicine, to give way to more modern regimens of combined NSAID therapy and intra-articular steroid injection. Hypouricaemic agents have revolutionised the management of gout but are not without their dangers, and there is a need for re-emphasis on the value of dietary measures and control of alcohol and diuretic use. At present only symptomatic management is available for chronic pyrophosphate- and hydroxyapatite-associated disease.
Arie
E
E
Rheumatology Unit, City Hospital, Nottingham, England.
Doherty
M
M
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D006801:Humans; D012216:Rheumatic Diseases / Q000188:drug therapy* / Q000503:physiopathology
D000894:Anti-Inflammatory Agents, Non-Steroidal