Macrophages in bronchoalveolar lavage fluid do not represent macrophages in granulomas of the lungs of BCG-infected mice.
In normal mice the phenotype of macrophages in the BAL fluid accurately reflects the phenotype found for the macrophages in the alveoli, but in BCG-infected mice the macrophages in the BAL fluid do not resemble those occurring in either the alveolar spaces or the granulomatous lesions.
Nibbering
P H
PH
Dept. of Infectious Diseases, University Hospital, Leiden, The Netherlands.
van de Heide
G A
GA
van Furth
R
R
D000911:Antibodies, Monoclonal; D001992:Bronchoalveolar Lavage Fluid / Q000032:analysis*; D002498:Centrifugation; D006099:Granuloma / Q000473:pathology*; D008171:Lung Diseases / Q000473:pathology*; D008264:Macrophages / Q000473:pathology*; D009164:Mycobacterium Infections / Q000473:pathology*; D009163:Mycobacterium bovis; D010641:Phenotype
D000911:Antibodies, Monoclonal