title: Secondary hypersplenism due to Caroli syndrome complicating immunosuppression in a renal allograft recipient.
abstract: The differential diagnosis of thrombocytopenia and leukocytopenia in renal allograft recipient can be troublesome. We report on a patient in whom the rare case of portal hypertension with secondary hypersplenism due to Caroli syndrome was detected to be the cause for the hematological disturbance. The management of the thereby complicated immunosuppressive regimen is discussed.
authors.affiliation: Department of Medicine II, University of Vienna, Austria.
authors.forename: B
authors.initials: B
authors.lastname: Watschinger
authors.forename: B
authors.initials: B
authors.lastname: Schwaighofer
authors.forename: F
authors.initials: F
authors.lastname: Wrba
authors.forename: E
authors.initials: E
authors.lastname: Pohanka
authors.forename: J
authors.initials: J
authors.lastname: Kovarik
mesh_terms: D000328:Adult; D001653:Bile Ducts, Intrahepatic / Q000002:abnormalities*; D003937:Diagnosis, Differential; D004108:Dilatation, Pathologic; D006801:Humans; D006971:Hypersplenism / Q000150:complications*; D006975:Hypertension, Portal / Q000150:complications*; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D016030:Kidney Transplantation; D007970:Leukopenia / Q000139:chemically induced / Q000209:etiology; D008297:Male; D013577:Syndrome; D013921:Thrombocytopenia / Q000139:chemically induced / Q000209:etiology
chemical_list: D007166:Immunosuppressive Agents