title: Prostaglandin infusion therapy for intermittent digital ischemia in a patient with mixed connective tissue disease. Case report and review of the literature.
abstract: Intermittent digital ischemia is frequently resistant to therapy despite various treatment modalities. Recent studies have reported the successful treatment of intermittent digital ischemia with prostaglandin infusion therapy. We present a severe case of intermittent digital ischemia associated with mixed connective tissue disease, responsive to prostaglandin E1 infusion therapy.
authors.affiliation: Department of Internal Medicine, University of South Florida College of Medicine, Tampa 33612.
authors.forename: L E
authors.initials: LE
authors.lastname: Cohen
authors.forename: I
authors.initials: I
authors.lastname: Faske
authors.forename: N A
authors.initials: NA
authors.lastname: Fenske
authors.forename: M A
authors.initials: MA
authors.lastname: Greist
mesh_terms: D000328:Adult; D000527:Alprostadil / Q000627:therapeutic use*; D000671:Amputation, Surgical; D005260:Female; D005385:Fingers / Q000601:surgery; D006801:Humans; D007262:Infusions, Intravenous; D008947:Mixed Connective Tissue Disease / Q000150:complications*; D011928:Raynaud Disease / Q000188:drug therapy* / Q000209:etiology
chemical_list: D000527:Alprostadil