title: Immunocytochemical techniques in stereotactic biopsy.
abstract: Conventional neuropathological stains, immunocytochemistry and cell culture can be performed on small tissue fragments obtained by stereotactic biopsy. A simple processing technique is described with particular attention to immunocytochemistry. The results of this technique are described for 34 specimens obtained from patients with low- and high-grade gliomas, lymphomas, pineal tumour and benign processes. The application of immunocytochemical techniques is of value in achieving a definitive diagnosis in the small tissue fragments obtained by stereotactic biopsy.
authors.affiliation: Department of Neurosurgery, University of Birmingham, UK.
authors.forename: E
authors.initials: E
authors.lastname: Hitchcock
authors.forename: C S
authors.initials: CS
authors.lastname: Morris
mesh_terms: D001254:Astrocytoma / Q000473:pathology; D001706:Biopsy / Q000379:methods*; D001932:Brain Neoplasms / Q000473:pathology*; D001933:Brain Stem / Q000473:pathology; D005910:Glioma / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods*; D008223:Lymphoma / Q000473:pathology; D010871:Pinealoma / Q000473:pathology; D013238:Stereotaxic Techniques