title: [Effect of prior psychopharmacotherapy on the development, clinical course and therapeutic effect of insulin coma in patients with schizophrenia].
abstract: In 123 patients the peculiarities of formation and effectiveness of insulin coma (IC) were studied under drug therapy as compared with 49 drug-free patients. Pharmacotherapy preceding the ICs produced uneven effect on its course. Artefact course of IC was most frequently observed after mageptil, chlorpromazine melipramine treatment, and to a lesser extent--after haloperidol, triphtazin, amitriptyline. It was virtually absent after benzodiazepines. The autonomic manifestations in IC and the harmony if its development and clinical picture, markedly changing under drug treatment, were exposed as predictors of the efficiency of IC therapy.
authors.forename: G Ia
authors.initials: GIa
authors.lastname: Avrutskiĭ
authors.forename: A A
authors.initials: AA
authors.lastname: Neduva
authors.forename: S V
authors.initials: SV
authors.lastname: Sulukhiia
authors.forename: A V
authors.initials: AV
authors.lastname: Iakovlev
mesh_terms: D000328:Adult; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D003295:Convulsive Therapy; D005260:Female; D006801:Humans; D008297:Male; D011619:Psychotropic Drugs / Q000627:therapeutic use*; D012559:Schizophrenia / Q000628:therapy*; D012565:Schizophrenic Psychology
chemical_list: D011619:Psychotropic Drugs
vernacular_title: Osobennosti vliianiia predshestvuiushcheĭ psikhofarmakoterapii na formirovanie, klinicheskuiu kartinu i terapevticheskiĭ éffekt insulinovykh kom u bol'nykh shizofrenieĭ.