[Heredity of granular corneal dystrophy (Groenouw I)].
Up-to date settlement, after 34 years, of a huge pedigree of 1391 individuals of which 77 were affected. The dominant autosomal mode of inheritance is confirmed. Nevertheless, discovery of an incomplete penetrance. The offspring of two affected individuals suggest that the heterozygotes and the affected homozygotes are identical. So an intermediate mode of inheritance would be excluded.
Cuendet
J F
JF
Beuret-Niedzielsky
A
A
Zografos
L
L
D003241:Consanguinity; D003317:Corneal Dystrophies, Hereditary / Q000235:genetics*; D005260:Female; D005799:Genes, Dominant; D006580:Genetic Carrier Screening; D006801:Humans; D008297:Male; D010375:Pedigree
Hérédité de la dystrophie granuleuse de la cornée (Groenouw I).