Thymic non-lymphoid cells cultured for transplantation purposes. Immunostimulatory effect on ataxia telangiectasia peripheral blood mononuclear cells.
The analysis of various methods of thymic non-lymphoid cells (TNLC) culture in vitro was performed. The TNLC obtained in culture of small thymic fragments in Eagle's minimal essential medium with 30% of fetal calf serum have been found to be biologically active as indicated by their ability to enhance proliferative activity and Il-2 production of peripheral blood mononuclear cells derived from ataxia telangiectasia patients.
Kaczmarek
L
L
Department of Pathomorphology, Child Health Center, Warsaw.
Michałkiewicz
J
J
Fedorowicz
M
M
Woźniewicz
B
B
D001259:Ataxia / Q000276:immunology*; D001685:Biological Factors / Q000378:metabolism / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D002648:Child; D003470:Culture Media / Q000494:pharmacology; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000166:cytology* / Q000187:drug effects; D013950:Thymus Gland / Q000166:cytology* / Q000378:metabolism
D001685:Biological Factors; D003470:Culture Media