title: Absence of end-diastolic umbilical artery blood flow predicts poor fetal outcome despite normal blood gases.
abstract: A case is reported in which the fetal acid-base status was assessed by means of cordocentesis in a fetus without end-diastolic umbilical artery blood flow. The absence of end-diastolic flow was not associated with acidosis or hypoxia. However, the fetal condition deteriorated 3 days later, which suggests that even with a normal fetal acid-base status, an extended margin of safety cannot be assumed with the absence of end-diastolic umbilical flow.
authors.affiliation: Department of Obstetrics and Gynecology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.
authors.forename: W
authors.initials: W
authors.lastname: Warren
authors.forename: S
authors.initials: S
authors.lastname: Ronkin
authors.forename: B
authors.initials: B
authors.lastname: Chayen
authors.forename: L
authors.initials: L
authors.lastname: Needleman
authors.forename: R J
authors.initials: RJ
authors.lastname: Wapner
mesh_terms: D000136:Acid-Base Equilibrium; D000328:Adult; D001783:Blood Flow Velocity; D001784:Blood Gas Analysis; D003971:Diastole; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D005315:Fetal Diseases / Q000097:blood / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome; D011296:Prenatal Diagnosis; D014463:Ultrasonography; D014469:Umbilical Arteries / Q000503:physiopathology