[Variations in the level of S antigen auto-antibodies and their relation to the development of retinitis pigmentosa (autosomal recessive genetic form)].
A group of 40 patients with retinitis pigmentosa (autosomal recessive) were studied. The levels of soluble retinal antigen (S antigen of human origin) auto-antibodies were measured by means of the enzyme-linked-immunosorbent assay. The results obtained were compared with those of a control population of 100 healthy subjects (p less than 0.001). A statistically significant correlation (r = 0.451, p less than 0.01) was observed when comparison was made between the anti-S levels and the time elapsed from the moment of retinitis pigmentosa diagnosis.
Heredia Garcia
C D
CD
Garcia Calderon
P A
PA
D000888:Antibodies, Anti-Idiotypic / Q000032:analysis*; D000941:Antigens / Q000032:analysis* / Q000097:blood; D019393:Arrestin; D001324:Autoantigens / Q000032:analysis* / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay; D005136:Eye Proteins / Q000032:analysis* / Q000097:blood; D006801:Humans; D012174:Retinitis Pigmentosa / Q000097:blood / Q000235:genetics / Q000276:immunology*
D000888:Antibodies, Anti-Idiotypic; D000941:Antigens; D019393:Arrestin; D001324:Autoantigens; D005136:Eye Proteins
Variation des titres d'auto-anticorps anti-antigène S et corrélation avec la durée d'évolution du processus de rétinite pigmentaire (forme génétique autosomique récessive).