title: A recessive tumor gene function in Drosophila is involved in cell adhesion.
abstract: The phenotypic effects of lethal (2) giant larvae mutations are due to unstructured growth of brain and imaginal disc cells in homozygous mutant larvae. Molecular properties of the wildtype l (2) gl protein and its tissue specificity of expression suggest that the protein is required for the adhesion of cells which are about the stop cell division and undergo terminal differentiation.
authors.affiliation: Institut für Biologie III, Universität Freiburg, Federal Republic of Germany.
authors.forename: O
authors.initials: O
authors.lastname: Schmidt
mesh_terms: D000818:Animals; D002448:Cell Adhesion; D004330:Drosophila / Q000235:genetics*; D005808:Genes, Recessive; D009154:Mutation; D009857:Oncogenes