Measurement of absolute flow rate in vessels using a stereoscopic DSA system.
We used a stereoscopic digital subtraction angiography (DSA) system to measure absolute blood flow rates in vessels. The magnification factor and the three-dimensional orientation of a selected vessel are obtained from automated analysis of stereoscopic DSA images. The cross-sectional area of the vessel is determined from the vessel diameter, which is measured with an iterative deconvolution technique. The time required for fluid to flow through a selected segment of a vessel is determined from the automated analysis of contrast medium 'time-density' curves. The effectiveness of these combined techniques was demonstrated in measurement of rates of both continuous and pulsatile flow in a vessel phantom, with the actual flow rate calibrated volumetrically or by an electromagnetic flowmeter. We have obtained accuracies in measured flow rates of approximately 5% and 18% for continuous and pulsatile flow respectively.
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Kurt Rossmann Laboratory, Department of Radiology, The University of Chicago, IL 60637.
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Chua
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Hoffman
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D000792:Angiography / Q000379:methods*; D001783:Blood Flow Velocity; D001808:Blood Vessels / Q000502:physiology*; D006801:Humans; D008961:Models, Structural; D011673:Pulsatile Flow; D011856:Radiographic Image Enhancement; D012039:Regional Blood Flow; D013382:Subtraction Technique