The influence of the interval between in vitro fertilization and embryo transfer and some other variables on treatment outcome.
This prospectively randomized study compares the outcome of 434 ETs 48 to 52 hours after insemination (day 2) and 324 ETs 72 to 76 hours after insemination (day 3). The influence of the interval between insemination and ET was assessed, as well as that of the number of embryos transferred, embryo quality, and the presence of supernumerary embryos. The mean number of embryos transferred after 2 and 3 days was equal (2.9 embryos/ET). The pregnancy rates per ET were not significantly different (21.9% versus 23.5%), but a higher percentage of viable pregnancies was observed after ET on day 3 (88.2% against 69.5% following ET on day 2). Treatment outcome was positively correlated with the number of embryos transferred and the presence of supernumerary embryos.
van Os
H C
HC
Department of Obstetrics and Gynaecology, Academic Hospital Rotterdam-Dijkzigt, The Netherlands.
Alberda
A T
AT
Janssen-Caspers
H A
HA
Leerentveld
R A
RA
Scholtes
M C
MC
Zeilmaker
G H
GH
D000022:Abortion, Spontaneous; D002986:Clinical Trials as Topic; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome; D011271:Pregnancy, Ectopic; D011446:Prospective Studies; D011897:Random Allocation; D013997:Time Factors