Obstruction of nasolacrimal ducts closely related to graft-versus-host disease after bone marrow transplantation.
A 2-year-old boy underwent bone marrow transplantation for severe aplastic anemia. Eighteen months later he developed chronic lung disease and dryness of the eyes. Ophthalmologic examination revealed obstruction of the nasolacrimal ducts and marked dilatation of the lacrimal sacs bilaterally. It seems likely that the nasolacrimal duct obstruction was a manifestation of chronic graft-versus-host disease.
Hanada
R
R
Division of Hematology/Oncology, Saitama Children's Medical Center, Japan.
Ueoka
Y
Y
D000741:Anemia, Aplastic / Q000150:complications / Q000601:surgery*; D016026:Bone Marrow Transplantation; D002675:Child, Preschool; D003607:Dacryocystitis / Q000209:etiology; D004108:Dilatation, Pathologic / Q000209:etiology; D006086:Graft vs Host Disease / Q000150:complications*; D006801:Humans; D007638:Keratoconjunctivitis Sicca / Q000209:etiology; D007765:Lacrimal Apparatus / Q000473:pathology; D007767:Lacrimal Duct Obstruction / Q000209:etiology*; D008297:Male; D012008:Recurrence