Phaeohyphomycotic cutaneous disease caused by Pleurophoma in a cardiac transplant patient.
A 56-y-old female cardiac transplant patient treated with cyclosporine and prednisone noted the onset of three nontender red nodules on the legs and arms after gardening. Biopsy of all lesions revealed inflammatory cells and hyphal elements in the dermis. The dematiaceous fungus cultured from biopsy tissue was a pycnidial-forming organism of the genus Pleurophoma. The lesions responded to the topical application of miconazole.
Dooley
D P
DP
Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas 78234-6200.
Beckius
M L
ML
Jeffery
B S
BS
McAllister
C K
CK
Radentz
W H
WH
Feldman
A R
AR
Rinaldi
M G
MG
Bailey
S R
SR
Keeling
J H
JH
D005260:Female; D016027:Heart Transplantation; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D008825:Miconazole / Q000008:administration & dosage; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology*; D009894:Opportunistic Infections / Q000382:microbiology*; D012871:Skin Diseases / Q000188:drug therapy / Q000382:microbiology*
D008825:Miconazole