Twin embryos in mares. I: From ovulation to fixation.
Recent findings on the origin and development of twins from ovulation (Day 0) to fixation (mean: Day 16) are reviewed. Available data show that almost all twins originate from multiple ovulations. Results of recent ultrasound studies indicate that the number of days between double ovulations does not affect the conception rate per ovum or embryo survival during the first 16 days after each ovulation. Embryo reduction is the natural elimination of excess embryos so that only one embryo enters the foetal stage. In two studies, embryo reduction before or on the day of fixation was not considered an important aspect of the natural correction of twins. Diameters and growth rates on Days 11 to 16 were similar between singletons and twins and the presence of two vesicles did not have a direct effect on their diameter other than that attributable to their age. Twin and singleton embryonic vesicles were mobile within the uterine lumen from the first day of detection (Days 9 to 11) to the day of fixation (mean: Day 16). In one study, the embryonic vesicles were in the uterine body for over 50 per cent of the time during Days 9 to 12 and thereafter were most often in the uterine horns. For twins of dissimilar size, the preference for uterine body versus horns appeared to be an independent function of each vesicle based on its age or size. After Day 12, the number of entries from the uterine body into the horns increased and the vesicles began a maximum mobility phase which continued until fixation.(ABSTRACT TRUNCATED AT 250 WORDS)
Ginther
O J
OJ
University of Wisconsin, Department of Veterinary Science, Madison 53706.
D000818:Animals; D020964:Embryo Loss / Q000662:veterinary; D005314:Embryonic and Fetal Development; D005260:Female; D006734:Horse Diseases; D006736:Horses / Q000502:physiology*; D009068:Movement; D010060:Ovulation; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000502:physiology*; D014429:Twins, Dizygotic; D014463:Ultrasonography / Q000662:veterinary; D014590:Uterine Contraction