Adverse drug reactions in the elderly.
There is limited evidence to suggest that the incidence of adverse drug reactions increases with patient age. Factors which may predispose the elderly to adverse drug reactions include multiple drug therapy and changes in pharmacokinetics and pharmacodynamics associated with ageing. Digoxin, diuretics and psychotropic drugs may be particularly hazardous in this age group.
Nolan
L
L
Royal College of Surgeons, Dublin, Ireland.
O'Malley
K
K
D000368:Aged; D000928:Antidepressive Agents / Q000009:adverse effects; D001569:Benzodiazepines / Q000009:adverse effects; D015331:Cohort Studies; D004077:Digoxin / Q000009:adverse effects; D004232:Diuretics / Q000009:adverse effects; D004342:Drug Hypersensitivity / Q000453:epidemiology; D004347:Drug Interactions; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D010599:Pharmacokinetics
D000928:Antidepressive Agents; D004232:Diuretics; D001569:Benzodiazepines; D004077:Digoxin