[The subpopulations and prognostic implication of mononuclear cells infiltration in pulmonary carcinoma].
Subpopulations of infiltrating mononuclear cells in 51 resected pulmonary carcinoma specimens were studied with immunohistochemical technique (ABC and PAP methods). The major constituent of the mononuclears was T-cells, especially the OKT8+ cells (T suppressor/cytotoxic). The local infiltration of the mononuclears in pulmonary carcinoma was related to the prognosis of the case. The more the OKT8+ and B1+ lymphocytes infiltrated, the longer the survival (rate obtained) whereas, the infiltration of some kinds of plasma cells tended to have a negative correlation with the prognosis of the case. The significance of the mononuclears in pulmonary carcinoma is discussed.
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D000230:Adenocarcinoma / Q000473:pathology; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D005260:Female; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000473:pathology*; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011379:Prognosis; D013601:T-Lymphocytes / Q000473:pathology