title: [Laboratory controls of heparin therapy with thrombin time, partial thromboplastin time and activated recalcification time].
abstract: For the laboratory control of a heparin therapy thrombin time, partial thromboplastin time and activated recalcification time are used. On account of distinct differences in the heparin sensitivity of these reactions an indication-related application is necessary. The ability of evidence and the possibility of establishing test-specific therapeutic regions are restricted by differences caused by reagents, individual variability and influence by accompanying haemostasiological changes. The own approach, taking into consideration the so-called heparin resistance, it presented.
authors.affiliation: Institut für Klinische Chemie und Laboratoriumsdiagnostik, Medizinischen Akademie Magdeburg.
authors.forename: G
authors.initials: G
authors.lastname: Lutze
authors.forename: H J
authors.initials: HJ
authors.lastname: Presser
authors.forename: H
authors.initials: H
authors.lastname: Urbahn
mesh_terms: D001780:Blood Coagulation Tests / Q000379:methods*; D004305:Dose-Response Relationship, Drug; D006493:Heparin / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D010314:Partial Thromboplastin Time; D013918:Thrombin Time; D014914:Whole Blood Coagulation Time
chemical_list: D006493:Heparin
vernacular_title: Laborkontrollen der Heparintherapie mit der Thrombinzeit, der partiellen Thromboplastinzeit und der aktivierten Rekalzifizierungszeit.