A vivid model of chiral recognition.
Hands can be used to demonstrate the three-point model of chiral recognition. The points of attachment are thumb, forefinger, and middle finger. This vivid model has the advantages of simplicity, perspicuity, and availability at any time, although two persons are necessary. It can be shown that two interactions are not sufficient for chiral recognition but that three attractive or two attractive and one repulsive attraction are needed. It can also be used to explain some possibilities of weakening or elusion of the three-point model.
Meyer
V R
VR
Institute of Organic Chemistry, University of Bern, Switzerland.
Rais
M
M
D006225:Hand; D008956:Models, Chemical; D011955:Receptors, Drug / Q000378:metabolism*; D013237:Stereoisomerism
D011955:Receptors, Drug