title: Cerebral aneurysms in childhood and adolescence.
abstract: In this study, 24 aneurysms occurring in 23 patients under the age of 18 years (mean 12 years) are analyzed. The male:female ratio was 2.8:1, and the youngest patient was 3 months old. Mycotic lesions and those associated with other vascular malformations were excluded. Forty-two percent of the aneurysms were located in the posterior circulation, and 54% were giant aneurysms. Presenting symptoms included subarachnoid hemorrhage in 13 and mass effect in 11. Several of these aneurysms were documented to rapidly increase in size over a 3-month to 2-year period of observation. All aneurysms were surgically treated: direct clipping was performed in 14; trapping with bypass in four; trapping alone in four; and direct excision with end-to-end anastomosis in two. The postoperative results were excellent in 21 aneurysms (87%), good in two (8%), and poor in one. The pathogenesis of cerebral aneurysms is reviewed.
authors.affiliation: Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota.
authors.forename: F B
authors.initials: FB
authors.lastname: Meyer
authors.forename: T M
authors.initials: TM
authors.lastname: Sundt
authors.forename: N C
authors.initials: NC
authors.lastname: Fode
authors.forename: M K
authors.initials: MK
authors.lastname: Morgan
authors.forename: G S
authors.initials: GS
authors.lastname: Forbes
authors.forename: J F
authors.initials: JF
authors.lastname: Mellinger
mesh_terms: D000293:Adolescent; D000792:Angiography; D002648:Child; D005260:Female; D006801:Humans; D007223:Infant; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000601:surgery*; D008297:Male