Fatal liver failure due to disulfiram.
We present the case of a 30-year-old man with disulfiram-induced hepatitis complicated by fatal liver failure. The disease followed a protracted course with an interval of 25 days between the onset of jaundice and the onset of encephalopathy. In this patient, the severity of the liver disease might have been due to reingestion of disulfiram shortly after the onset of jaundice.
Cereda
J M
JM
Unité de Recherches de Physiopathologie Hépatique, INSERM U24, Hôpital Beaujon, Clichy, France.
Bernuau
J
J
Degott
C
C
Rueff
B
B
Benhamou
J P
JP
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000328:Adult; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000473:pathology; D004221:Disulfiram / Q000009:adverse effects*; D006501:Hepatic Encephalopathy / Q000139:chemically induced; D006801:Humans; D008099:Liver / Q000473:pathology; D008297:Male
D004221:Disulfiram