title: Automated DNA sequencing methods for detection and analysis of mutations: applications to the Lesch-Nyhan syndrome.
authors.affiliation: Institute for Medical Genetics, Baylor College of Medicine, Houston, TX.
authors.forename: A
authors.initials: A
authors.lastname: Edwards
authors.forename: R A
authors.initials: RA
authors.lastname: Gibbs
authors.forename: P N
authors.initials: PN
authors.lastname: Nguyen
authors.forename: W
authors.initials: W
authors.lastname: Ansorge
authors.forename: C T
authors.initials: CT
authors.lastname: Caskey
mesh_terms: D001483:Base Sequence; D002872:Chromosome Deletion; D004247:DNA / Q000235:genetics*; D005260:Female; D006580:Genetic Carrier Screening; D006801:Humans; D007041:Hypoxanthine Phosphoribosyltransferase / Q000235:genetics*; D007926:Lesch-Nyhan Syndrome / Q000175:diagnosis / Q000201:enzymology / Q000235:genetics*; D008297:Male; D009154:Mutation; D010375:Pedigree; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012091:Repetitive Sequences, Nucleic Acid; D015183:Restriction Mapping
chemical_list: D004247:DNA; D007041:Hypoxanthine Phosphoribosyltransferase