[Molecular organization of protein-lipid components of the crystalline lens].
Lens transparency is primarily a physical phenomenon and is a manifestation of the lens structural organization. Traditionally the lens is considered as a "sac filled with proteins uniformly". Such studies have described overall average properties of the lens but have dealt with neither structural nor functional inhomogeneities in the lens tissue. All morphological, biochemical and physiological processes of the lens are aimed at the maintenance of transparency and refractive index. Minimizing of the lens light scatter is created in the lens by the processes that organize regularity at two structural levels: the fiber cytoplasmic matrix (cytoskeleton and soluble protein) and the fiber cell plasma membrane. Biochemical fractions of the lens are considered that are responsible for the physical basis of lens transparency.
Babizhaev
M A
MA
D000818:Animals; D002386:Cataract / Q000209:etiology; D003459:Crystallins / Q000032:analysis*; D006801:Humans; D007908:Lens, Crystalline / Q000032:analysis*; D015227:Lipid Peroxidation; D008055:Lipids / Q000032:analysis*; D010455:Peptides / Q000032:analysis
D003459:Crystallins; D008055:Lipids; D010455:Peptides
Molekuliarnaia organizatsiia belkovo-lipidnykh komponentov khrustalika glaza.