title: Subarachnoid analgesia with hyperbaric 0.5% bupivacaine: effect of a 60-min period of sitting.
abstract: A prospective randomised study of the effect when the patient remained sitting for 2 (Group-2) or 60 min (Group-60) before being put in the supine horizontal position, was evaluated in 12 patients, aged 39-67 years and given a spinal anesthesia with 4 ml 0.5% bupivacaine in 8% glucose (hyperbaric). The maximal cephalad spread of analgesia was obtained after 12.5 min (median) in Group-2 and 75 min in Group-60 (P less than 0.01). The spread of sensory analgesia went to T-6 (Group-2) and L3 (Group-60) after 60 min (P less than 0.01). After 90 min the spread went to T6.5 in Group-60, the difference being statistically significant (P less than 0.001). Given as median and range the maximum cephalad spread in Group-2 was T6(T3-T10) and in Group-60 T6.5 (T2-T10).
authors.affiliation: Department of Anesthetics, Nykøbing Falster District Hospital, Denmark.
authors.forename: H M
authors.initials: HM
authors.lastname: Povey
authors.forename: J
authors.initials: J
authors.lastname: Jacobsen
authors.forename: J
authors.initials: J
authors.lastname: Westergaard-Nielsen
mesh_terms: D000328:Adult; D000368:Aged; D000698:Analgesia; D000775:Anesthesia, Spinal; D001274:Atmospheric Pressure; D002045:Bupivacaine; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011187:Posture; D011446:Prospective Studies; D011897:Random Allocation; D012996:Solutions; D013346:Subarachnoid Space; D013997:Time Factors
chemical_list: D012996:Solutions; D002045:Bupivacaine