Mechanism of action of interleukin-2 receptor (IL-2R) monoclonal antibody (MAb) therapy: target cell depletion or inhibition of function?
Tellides
G
G
Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Great Britain.
Dallman
M J
MJ
Morris
P J
PJ
D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D006085:Graft Survival; D016027:Heart Transplantation; D007376:Interleukin-2 / Q000276:immunology*; D016030:Kidney Transplantation; D051381:Rats; D011917:Rats, Inbred Lew; D011919:Rats, Inbred Strains; D015375:Receptors, Interleukin-2 / Q000276:immunology*; D014184:Transplantation, Homologous
D000911:Antibodies, Monoclonal; D007376:Interleukin-2; D015375:Receptors, Interleukin-2