Errors in the isotopic estimations of hepatic glycogen synthesis and glucose output.
Ignoring the reality of glucose in equilibrium glucose-6P cycling in the liver in vivo produces large potential errors in the isotopic quantitation of percentage contributions of direct and indirect pathways of glycogen synthesis and of hepatic glucose output.
Rognstad
R
R
Lemontree Research Institute, Sylmar, CA 91342.
D000818:Animals; D002250:Carbon Radioisotopes; D005943:Gluconeogenesis; D005947:Glucose / Q000378:metabolism*; D006019:Glycolysis; D008099:Liver / Q000378:metabolism*; D008112:Liver Glycogen / Q000096:biosynthesis*; D008433:Mathematics; D008962:Models, Theoretical; D011865:Radioisotope Dilution Technique
D002250:Carbon Radioisotopes; D008112:Liver Glycogen; D005947:Glucose