title: [The role of elastolytic enzymes and smoking in the pathogenesis of emphysema].
abstract: Author provides a survey on the incidence rate of emphysema and of its social and economic consequences as well as available experimental data. Discussing her own results the significance of endogenous enzymes, smoking and of factors maintaining protease/antiprotease equilibrium are mentioned. The prophylactive and therapeutic potentials of currently experimental agents are evaluated.
authors.forename: K
authors.initials: K
authors.lastname: Szemenyei
mesh_terms: D000818:Animals; D004547:Elastic Tissue / Q000648:ultrastructure; D008168:Lung / Q000201:enzymology* / Q000648:ultrastructure; D010196:Pancreatic Elastase / Q000378:metabolism*; D010447:Peptide Hydrolases / Q000378:metabolism; D011656:Pulmonary Emphysema / Q000201:enzymology* / Q000209:etiology; D051381:Rats; D011919:Rats, Inbred Strains; D012907:Smoking / Q000009:adverse effects*
chemical_list: D010447:Peptide Hydrolases; D010196:Pancreatic Elastase
vernacular_title: Az elasztolitikus enzimek és a dohányzás szerepe az emphysema patogenezisében.