title: Low-grade primary cutaneous adenosquamous (mucoepidermoid) carcinoma. Report of a case and review of the literature.
abstract: A case of histologically low-grade primary cutaneous adenosquamous carcinoma is reported. Dermal invasion was limited to the superficial dermis. This pattern contrasts sharply with the deeply infiltrating pattern of previously reported examples of cutaneous adenosquamous carcinoma. Less aggressive biologic behavior is expected from this histologically low-grade variant when compared to the high potential for recurrence and metastasis of previously reported cutaneous adenosquamous carcinoma. Immunohistochemical studies support an eccrine origin for this tumor.
authors.affiliation: Department of Dermatology, Johns Hopkins Medical Institutions, Baltimore, MD 21205.
authors.forename: K J
authors.initials: KJ
authors.lastname: Friedman
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D004848:Epithelium / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000473:pathology*