title: Effect of drugs on histamine radio-enzyme assay.
abstract: The effect of over 200 drugs and other compounds on histamine radio-enzyme assay was studied. Some muscle relaxants (e.g. alcuronium), some sympathomimetics (e.g. dopamine, isoxsuprine, tyramine and possibly phenylethylamine), antimalarial drugs, procaine, procainamide, Berenil and serotonin were potent compounds to interfere with this assay. In some special cases still potentially inhibitory drugs seemed to be some muscle relaxants (e.g. vecuronium, pancuronium and tubocurarine), antidepressants, antihistamines (e.g. cimetidine, ranitidine and diphenhydramine), chinidin, disopyramide, tolazoline and salazosulfapyridine.
authors.affiliation: Department of Dermatology, University of Kuopio, Finland.
authors.forename: R J
authors.initials: RJ
authors.lastname: Harvima
authors.forename: I T
authors.initials: IT
authors.lastname: Harvima
authors.forename: E O
authors.initials: EO
authors.lastname: Kajander
authors.forename: I M
authors.initials: IM
authors.lastname: Penttilä
authors.forename: M
authors.initials: M
authors.lastname: Horsmanheimo
authors.forename: J E
authors.initials: JE
authors.lastname: Fräki
mesh_terms: D006632:Histamine / Q000032:analysis*; D007124:Immunoenzyme Techniques; D004364:Pharmaceutical Preparations; D011863:Radioimmunoassay
chemical_list: D004364:Pharmaceutical Preparations; D006632:Histamine