Second neoplasms in Hodgkin's disease: current controversies.
Aggressive, multimodal treatment of Hodgkin's disease has led to dramatic increases in survival but not without significant early toxicity and late complications. The most serious late complication is the development of a secondary neoplasm. These secondary cancers include acute nonlymphocytic leukemia, non-Hodgkin's lymphoma, and various solid tumors.
Zarrabi
M H
MH
Department of Medicine, Veterans Administration Medical Center, Northport, New York.
Rosner
F
F
D000293:Adolescent; D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy / Q000009:adverse effects; D005260:Female; D006689:Hodgkin Disease / Q000628:therapy*; D006801:Humans; D007223:Infant; D007558:Italy; D007938:Leukemia / Q000139:chemically induced / Q000453:epidemiology; D007953:Leukemia, Radiation-Induced / Q000209:etiology; D008228:Lymphoma, Non-Hodgkin / Q000139:chemically induced / Q000453:epidemiology / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000139:chemically induced / Q000453:epidemiology; D009378:Neoplasms, Multiple Primary / Q000139:chemically induced / Q000453:epidemiology / Q000209:etiology*; D009381:Neoplasms, Radiation-Induced / Q000209:etiology; D011878:Radiotherapy / Q000009:adverse effects*; D014481:United States