Progress in the histomorphometry of the microcirculatory system.
Following a short review of the limits set to the procedures applied so far to measure quantitative changes in wall tissue of microvessels, a new measuring method is presented. It detect morphological reactions of the microcirculatory system on the grounds of changes in the numerical density of selectively visualized microvessels and their classification according to the external diameter by means of the automatic microscopic image analysing system QUANTIMET. Influences of structurally based and/or postmortal changes of the lumen wideness on the measurement are excluded by the automatic subtraction of the lumen area.
Herrmann
H J
HJ
Central Institute for Heart and Circulation Research, Berlin, G.D.R.
Mühlig
P
P
Kühne
C
C
Blödner
R
R
D000818:Animals; D007091:Image Processing, Computer-Assisted; D008833:Microcirculation / Q000473:pathology*