title: Myocardial abscess after silent myocardial infarction.
abstract: A 73 year old male was hospitalised with fever of unknown origin and episodes with septic shock. During the in-hospital stay the clinical situation deteriorated rapidly, and E. coli was isolated from bloodcultures. All routine investigations revealed no specific abnormalities except for the electrocardiogram, which showed an old anterior-apical infarction although no history of cardiac disease was present. A CT-scan of the thorax and a scintigraphy using labelled autologous leucocytes made the diagnosis of a myocardial abscess, located in an apical aneurysm, probable. No other site of infection could be found and so it was decided to perform an aneurysmectomy with abscess evacuation in combination with extensive antibiotic treatment. After two years the patient is doing well. Only one case of survival has been reported before, also after surgical intervention. This underlines the importance of early diagnosis and aggressive therapy especially with regard to the reported high incidence of cardiac rupture.
authors.affiliation: Department of Internal Medicine, Sophia Hospital, Zwolle, The Netherlands.
authors.forename: E E
authors.initials: EE
authors.lastname: Weernink
authors.forename: M J
authors.initials: MJ
authors.lastname: de Boer
authors.forename: A
authors.initials: A
authors.lastname: Brutel de la Rivière
mesh_terms: D000038:Abscess / Q000188:drug therapy / Q000601:surgery*; D000368:Aged; D003131:Combined Modality Therapy; D004338:Drug Combinations / Q000627:therapeutic use; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000601:surgery*; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000601:surgery*; D006322:Heart Aneurysm / Q000601:surgery; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000150:complications*; D013420:Sulfamethoxazole / Q000627:therapeutic use; D013927:Thrombosis / Q000601:surgery; D014295:Trimethoprim / Q000627:therapeutic use; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
chemical_list: D004338:Drug Combinations; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim; D013420:Sulfamethoxazole