Lung eicosanoid metabolism.
Eicosanoids are metabolites of the essential fatty acid, arachidonic acid, which is an integral part of all cell membranes. Membrane damage (as in lung injury) and stretching of tissues are recognized stimuli for lung prostaglandin release, indicating a spectrum of possible roles of eicosanoids in the function of the normal and diseased lung. This article reviews the most pertinent issues regarding the roles of arachidonic acid metabolites in the lung.
Voelkel
N F
NF
Cardiovascular Pulmonary Research Laboratory, University of Colorado Health Sciences Center, Denver.
Stenmark
K R
KR
Westcott
J Y
JY
Chang
S W
SW
D000818:Animals; D001249:Asthma / Q000378:metabolism; D004537:Eicosanoic Acids / Q000378:metabolism*; D006801:Humans; D008168:Lung / Q000378:metabolism*; D011652:Pulmonary Circulation; D012128:Respiratory Distress Syndrome / Q000378:metabolism
D004537:Eicosanoic Acids