title: [Quantitative evaluation of the nucleolus organizer regions (NORs) in malignant melanoma of the skin: is it a new prognosis index?].
abstract: Nucleolar Organizer Region-associated proteins (NORs) have been evaluated on paraffin sections of a series of cutaneous malignant melanomas, stage IA at the time of the initial diagnosis. A significant difference (P less than 0.001) was found between the numbers of AgNORs in the cases which developed metastases and those without metastases: increasing values of AgNORs representing increased risk of metastases.
authors.forename: C
authors.initials: C
authors.lastname: Gambini
authors.forename: A R
authors.initials: AR
authors.lastname: Sementa
authors.forename: L
authors.initials: L
authors.lastname: Borgiani
authors.forename: L
authors.initials: L
authors.lastname: Massone
authors.forename: S
authors.initials: S
authors.lastname: Rovida
authors.forename: M
authors.initials: M
authors.lastname: Canepa
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000473:pathology* / Q000556:secondary; D008875:Middle Aged; D009367:Neoplasm Staging; D009697:Nucleolus Organizer Region / Q000473:pathology*; D011379:Prognosis; D012307:Risk Factors; D012878:Skin Neoplasms / Q000473:pathology*
vernacular_title: La valutazione quantitativa delle regioni organizzatrici del nucleolo (NORs) nel melanoma maligno cutaneo: un nuovo indice prognostico?