title: [Immunology of epilepsy].
abstract: An idea of the experimental and the clinical immunology of epilepsy has been presented in this paper. Experimental investigations suggest that the causality of epilepsy to molecular-immunological level has not been identified. Clinical observations testify the disordered immunologic homeostasis by primary effect of cerebral damage or, more frequently, by secondary expression of long-term anticonvulsant therapy. The behaviour of humoral immunology in chronic epileptic patients indicates the hiperimmune condition of organism; more evident effect of monotherapy by anticonvulsants on the level (rather lowered) of some immunoglobulins; the presence of anti-tissue antibodies in the absence of known autoimmune diseases. Cell immunity shows the tendency of suppression regardless of the form of epilepsy and its treatment.
authors.forename: D
authors.initials: D
authors.lastname: Sepić-Grahovac
authors.forename: J
authors.initials: J
authors.lastname: Sepcić
authors.forename: D
authors.initials: D
authors.lastname: Rukavina
mesh_terms: D001323:Autoantibodies / Q000032:analysis; D004827:Epilepsy / Q000276:immunology*; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis
chemical_list: D001323:Autoantibodies; D007136:Immunoglobulins
vernacular_title: Imunologija epilepsije.