[New possibilities of treating acute angioedema caused by C1-inhibitor deficiency].
The authors discuss diagnostic difficulties in 12 cases of hereditary angioneurotic edema due to C1-esterase inhibitor (C1-INH deficiency). Emphasis is on the treatment of the acute attacks with intravenous infusions of C1-inhibitor concentrate (Boehring, West Germany). This proved to be a very efficient and safe therapy, leading to a prompt disappearance of all clinical symptoms. Throughout 12 months following the infusions, indices of the liver function remained within the normal range, and anti-Hbs and anti-HIV tests were negative.
Obtułowicz
K
K
Głuszko
P
P
Radwan
J
J
Szczeklik
A
A
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000799:Angioedema / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics; D003174:Complement C1 Inactivator Proteins / Q000172:deficiency / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged
D003174:Complement C1 Inactivator Proteins
Nowe mozliwości leczenia ostrych obrzeków naczynioruchowych u chorych z niedoborem inhibitora C1-esterazy.