Human type II collagen gene (COL2A1) assigned to chromosome 12q13.1-q13.2 by in situ hybridization with biotinylated DNA probe.
We have made a regional assignment of the type II collagen gene (COL2A1) on human chromosome 12 by means of an in situ hybridization technique with a biotinylated DNA probe. The precise localization of the signal was mapped to the band 12q13.1-q13.2. This result was in agreement with the previous mapping by isotopic in situ hybridization technique (12q13.1-q13.2), but not with the result of Southern hybridization analysis using somatic cell hybrids (12q14.3).
Takahashi
E
E
Hori
T
T
Lawrence
J B
JB
McNeil
J
J
Singer
R H
RH
O'Connell
P
P
Leppert
M
M
White
R
R
D002871:Chromosome Banding; D002874:Chromosome Mapping; D002881:Chromosomes, Human, Pair 12; D003094:Collagen / Q000235:genetics*; D015342:DNA Probes; D006801:Humans; D009693:Nucleic Acid Hybridization
D015342:DNA Probes; D003094:Collagen