title: Nocardia asteroides keratitis presenting as a persistent epithelial defect.
abstract: An elderly male presented with epithelial defect which resisted all medical and therapeutic approaches until Gram stain and cultural report documented the presence of Nocardia asteroides of the offending organism. A 3-month course of chronic keratitis with persistent epithelial defect resolved in 48 h following the use of topical trimethoprim-sulfamethoxazole.
authors.affiliation: Division of Ophthalmology, Nassau County Medical Center, East Meadow.
authors.forename: H D
authors.initials: HD
authors.lastname: Perry
authors.forename: J S
authors.initials: JS
authors.lastname: Nauheim
authors.forename: E D
authors.initials: ED
authors.lastname: Donnenfeld
mesh_terms: D000368:Aged; D001431:Bacteriological Techniques; D003315:Cornea / Q000473:pathology; D004338:Drug Combinations / Q000008:administration & dosage; D004848:Epithelium / Q000473:pathology; D006801:Humans; D007262:Infusions, Intravenous; D007634:Keratitis / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D008297:Male; D009617:Nocardia Infections / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D009616:Nocardia asteroides / Q000648:ultrastructure; D013420:Sulfamethoxazole / Q000008:administration & dosage; D014295:Trimethoprim / Q000008:administration & dosage; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
chemical_list: D004338:Drug Combinations; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim; D013420:Sulfamethoxazole