HLA-D/DR identity results in a positive CML reaction.
Investigating HLA-A, HLA-B, HLA-C, and HLA-DR antigens, MLR, CML, and PLT reactivity in two unrelated persons it was found that despite their HLA-D/DR identity cytotoxic T lymphocytes (CTL) could be induced in the CML assay. The HLA-DP antigens proved to provide the necessary proliferative impetus for the generation of CTL.
Buc
M
M
Department of Microbiology and Immunology, Faculty of Medicine, Comenius University, Bratislava.
Porubská
S
S
Bencová
M
M
Nyulassy
S
S
Stefanovic
J
J
D003602:Cytotoxicity, Immunologic; D005260:Female; D006680:HLA Antigens / Q000032:analysis; D006681:HLA-D Antigens / Q000276:immunology*; D006684:HLA-DR Antigens / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D016030:Kidney Transplantation; D008297:Male; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology
D006680:HLA Antigens; D006681:HLA-D Antigens; D006684:HLA-DR Antigens