[Decrease in repair processes in lymphocytes of workers exposed to heavy metals].
Mechanisms of DNA repair in lymphocytes of persons having occupational contact with heavy metal salts for at least 10 years were investigated. The long-term exposure to heavy metal salts did not result in development of mechanisms of adaptation to the respective metals, as shown by increased DNA sensitivity to these compounds and by decrease in the repair activity. However, in some cases, resistance to other mutagens, 4-NQO, in particular, was observed.
Chopikashvili
L V
LV
North-Osetian K. L. Khetagurov State University, Ordzonikidze.
Vasil'eva
I M
IM
L'vova
G N
GN
Zasukhina
G D
GD
Bobyleva
L A
LA
D003035:Cobalt / Q000633:toxicity*; D004249:DNA Damage; D004260:DNA Repair; D004781:Environmental Exposure; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism; D008982:Molybdenum / Q000633:toxicity*; D009153:Mutagens
D009153:Mutagens; D003035:Cobalt; D008982:Molybdenum
Snizhenie reparativnykh protsessov v limfotsitakh rabochikh, kontaktiruiushchikh s tiazhelymi metallami.