title: Characterization and antibiotic sensitivity of Campylobacter jejuni and Campylobacter coli isolated from children at the Lagos University Teaching Hospital (LUTH), Lagos, Nigeria.
abstract: One hundred and thirteen rectal swabs and 87 faecal samples obtained from the Paediatric casualty of the Lagos University Teaching Hospital, Lagos, Nigeria were processed for Campylobacter jejuni/coli. Twenty-two (11%) of the specimens were positive for C. jejuni. Biotyping results showed that nine (41%) and eight (36%) belonged to C. jejuni biotypes I and II respectively, while three (14%) and two (9%) belonged to C. coli biotypes I and II. Serotyping results revealed that C. jejuni biotypes I and II and C. coli biotypes I and II belonged to different serotypes with serotypes A9 and A36 being the most prevalent. In-vitro antibiotic sensitivity testing using the disc method showed that 18 (82%) of the Campylobacter jejuni/coli isolates were sensitive to erythromycin and nalidixic acid, while 16 (73%) were sensitive to streptomycin. All were resistant to penicillin, while four (18%) and six (27%) were sensitive to tetracycline and cloxacillin respectively. We therefore recommend the use of erythromycin and streptomycin for cases of Campylobacter enteritis requiring antimicrobial therapy in Lagos, Nigeria.
authors.affiliation: Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, Nigeria.
authors.forename: A O
authors.initials: AO
authors.lastname: Coker
authors.forename: B
authors.initials: B
authors.lastname: Olaiya
authors.forename: C L
authors.initials: CL
authors.lastname: Obi
authors.forename: S A
authors.initials: SA
authors.lastname: Alabi
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D015373:Bacterial Typing Techniques; D002167:Campylobacter / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D002168:Campylobacter fetus / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000382:microbiology; D004917:Erythromycin / Q000494:pharmacology; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D009268:Nalidixic Acid / Q000494:pharmacology; D009549:Nigeria; D012703:Serotyping; D013307:Streptomycin / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D009268:Nalidixic Acid; D004917:Erythromycin; D013307:Streptomycin