title: Do local analgesics injected at the time of third molar removal under general anaesthesia reduce significantly post operative analgesic requirements? A double-blind controlled trial.
abstract: A prospective, controlled, randomised, double-blind trial suggested that: 1. The use of bupivacaine 0.5% plain and prilocaine 3% with felypressin 0.03 i.u./ml. as peroperative local analgesics reduce postoperative pain scores recorded on the first postoperative morning (P less than 0.05). 2. Bupivacaine 0.5% plain reduces postoperative opiate requirements (P less than 0.025). 3. Patients do not find peroperative bilateral inferior alveolar and lingual nerve blocks with buccal infiltrations significantly unpleasant. Thus peri-operative bupivacaine 0.5% is a valuable adjunct to third molar removal under general anaesthesia.
authors.affiliation: Department of Oral Surgery, Plymouth General Hospital, Devon.
authors.forename: J R
authors.initials: JR
authors.lastname: Tuffin
authors.forename: D R
authors.initials: DR
authors.lastname: Cunliffe
authors.forename: S R
authors.initials: SR
authors.lastname: Shaw
mesh_terms: D000293:Adolescent; D000328:Adult; D000700:Analgesics / Q000008:administration & dosage; D000766:Anesthesia, Dental; D000768:Anesthesia, General; D002045:Bupivacaine / Q000008:administration & dosage*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007430:Intraoperative Care; D008297:Male; D008964:Molar, Third / Q000601:surgery*; D010149:Postoperative Pain / Q000517:prevention & control*; D011318:Prilocaine / Q000008:administration & dosage*; D011446:Prospective Studies; D011897:Random Allocation; D014081:Tooth Extraction
chemical_list: D000700:Analgesics; D011318:Prilocaine; D002045:Bupivacaine