Rheumatoid papules: lesions showing features of vasculitis and palisading granuloma.
Whether palisading granuloma formation occurs with leukocytoclastic vasculitis in rheumatoid nodules and in histopathologically similar conditions is debatable. Patients with high titers for rheumatoid factor and severe erosive rheumatoid arthritis are at risk for both rheumatoid vasculitis and rheumatoid nodules. A patient with all of these features developed a papular eruption. These papules showed clinicopathologic features both of leukocytoclastic vasculitis and of early palisading granuloma. Lesions resolved slowly with low-dose oral corticosteroid therapy. It is proposed that these lesions be called rheumatoid papules and that they may represent a link between vasculitis and the palisaded granulomatous reaction seen in rheumatoid nodules.
Smith
M L
ML
Department of Pediatrics, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27103.
Jorizzo
J L
JL
Semble
E
E
Arrington
J H
JH
White
W L
WL
D001707:Biopsy, Needle; D005260:Female; D006099:Granuloma / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D012218:Rheumatoid Nodule / Q000150:complications / Q000276:immunology / Q000473:pathology*; D012871:Skin Diseases / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D014657:Vasculitis / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*
D011241:Prednisone