[Linkage disequilibrium and DNA markers associated with the gene for cystic fibrosis].
R.F.L.P. (Restriction Fragment Length Polymorphism) observed with tightly linked probes to the CF gene allows us to calculate the standardised linkage disequilibrium between CF and these markers. This approach in combination with others strategies permits to situate the gene between D9 and G2. The conditional probabilities observed with these haplotypes modify the classical genetic of CF.
Ferec
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Laboratoire de Biologie moléculaire, Brest.
Verlingue
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Parent
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D003550:Cystic Fibrosis / Q000235:genetics*; D005817:Genetic Counseling; D008040:Genetic Linkage; D005819:Genetic Markers; D006239:Haplotypes; D006801:Humans; D011336:Probability
D005819:Genetic Markers
Déséquilibre de liaison et marqueurs de l'ADN associés au gène de la fibrose kystique.