title: The effect of placebo in the alcohol withdrawal state.
abstract: A double-blind study of the effects of 100% oxygen and medical air on the alcohol withdrawal state (AWS) showed no significant difference between the two conditions using a random sample of 50 subjects in each treatment group. However, both gases produced a therapeutic effect in over half the cases in each group. These results could be related to the possible opioid properties of the placebo response.
authors.affiliation: South African Brain Research Institute, Johannesburg, South Africa.
authors.forename: F J
authors.initials: FJ
authors.lastname: Lichtigfeld
authors.forename: M A
authors.initials: MA
authors.lastname: Gillman
mesh_terms: D000328:Adult; D000388:Air; D000437:Alcoholism / Q000523:psychology / Q000534:rehabilitation*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D000431:Ethanol / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010102:Oxygen Inhalation Therapy; D012718:Set, Psychology; D013375:Substance Withdrawal Syndrome / Q000523:psychology / Q000534:rehabilitation*
chemical_list: D000431:Ethanol