Metastases to and from the upper aerodigestive tract in the population of Rochester, Minnesota, 1935-1984.
The present investigation is the first population-based study to provide incidence and clinicopathologic data for metastases to and from the upper aerodigestive tract (UAT). In a patient cohort with relatively minimal referral bias it was determined that cervical and distant metastases occurred in 21% and 2%, respectively, of UAT carcinomas by the time of diagnosis; incidence rates per 100,000 person-years for cervical and distant metastases from UAT carcinomas were 2.8 and 0.3, respectively; occult primary lesions represented 3.8% of all UAT carcinomas; 3.6% of all invasive UAT carcinomas were actually metastatic from another body site; and the clinicopathologic literature has overestimated the prevalence of metastases at diagnosis relative to UAT carcinomas.
Bouquot
J E
JE
Department of Oral Pathology, West Virginia University School of Dentistry, Morgantown 26506.
Weiland
L H
LH
Kurland
L T
LT
D000230:Adenocarcinoma; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell; D002295:Carcinoma, Transitional Cell; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006306:Health Surveys; D006801:Humans; D008297:Male; D008545:Melanoma; D008875:Middle Aged; D008910:Minnesota; D009362:Neoplasm Metastasis; D009959:Oropharyngeal Neoplasms / Q000453:epidemiology* / Q000556:secondary; D010610:Pharyngeal Neoplasms / Q000453:epidemiology*