A novel approach to electrode signal analysis for glucose determination.
The methodology proposed in this presentation consists in considering the stationary Pt-electrode of an electrocatalytic sensor aimed at glucose measurement together with the reference electrode as a "black box" for which a mathematical model is assumed. The model correlates selected features of the output signal to the concentration of glucose and of interfering substances (urea, amino acids) and to their interactions. The model parameters are experimentally identified. During the measurement, the values of previously selected features of sensor output signal are determined; then they serve as the input data for computation of concentrations of glucose and of interfering substances.
Zawicki
I
I
Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Science, Warszawa.
Nalecz
M
M
Dudzinska
E
E
D015374:Biosensing Techniques; D001786:Blood Glucose / Q000032:analysis*; D004566:Electrodes; D066298:In Vitro Techniques; D008954:Models, Biological
D001786:Blood Glucose