[Explantation, incubation and reimplantation of bone marrow cells as a means of treating acute radiation sickness in various species of animals].
In experiments with mice, rats, guinea pigs, and dogs subjected to whole-body irradiation a favourable effect of postirradiation explantation, incubation, under suboptimal conditions, and reimplantation of bone marrow cells was shown. The effect was perhaps associated with the enhanced recovery of stem cells, their primary differentiation into a granulocytic series, and activation of bone marrow regeneration.
Rozhdestvenskiĭ
L M
LM
Shcherbova
E N
EN
Limarenko
V N
VN
D000208:Acute Disease; D000818:Animals; D001853:Bone Marrow / Q000187:drug effects / Q000528:radiation effects; D016026:Bone Marrow Transplantation; D003114:Colony-Forming Units Assay; D046508:Culture Techniques; D004285:Dogs; D005260:Female; D005720:Gamma Rays; D006168:Guinea Pigs; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D011833:Radiation Injuries, Experimental / Q000401:mortality / Q000628:therapy*; D051381:Rats; D013997:Time Factors
Eksplantatsiia, inkubatsiia i reimplantatsiia kletok kostnogo mozga kak sposob lecheniia ostroĭ luchevoĭ bolezni u zhivotnykh raznykh vidov.