Hyperprolactinemia and female infertility.
Hyperprolactinemia is a common endocrine cause of infertility in women. The pathophysiology of hyperprolactinemia in infertility is understood incompletely; however, the adverse effects of high circulating levels of prolactin on the hypothalamic-pituitary-ovarian axis cause chronic anovulation and other defects of ovarian function. Mechanisms for prolactin-induced anovulation have been postulated, and there are several contemporary approaches to the diagnosis and treatment of prolactin-secreting pituitary adenomas.
Jones
E E
EE
Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, CT 06510.
D000568:Amenorrhea / Q000209:etiology; D000858:Anovulation / Q000209:etiology; D005260:Female; D005687:Galactorrhea / Q000209:etiology; D006801:Humans; D006966:Hyperprolactinemia / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology; D007247:Infertility, Female / Q000209:etiology*; D010053:Ovary / Q000503:physiopathology; D011388:Prolactin / Q000502:physiology
D011388:Prolactin