title: [Clinico-immunologic effectiveness of chlorophyllypt in the treatment of acute destructive pneumonia].
abstract: An attempt has been made to replace antibiotics by chlorophyllypt (0.25 per cent solution in physiological sodium chloride solution administered by intravenous drip). The clinical, laboratory and X-ray parameters in 22 patients treated by this drug normalized in earlier terms than those in 19 patients who received the traditional antibiotic therapy. Chlorophyllypt was found to have the immunocorrective effect manifested by the normalization of the T-lymphocyte number and their theophylline-resistant subpopulation. No such an effect was achieved when broad-action antibiotics were used.
authors.forename: S I
authors.initials: SI
authors.lastname: Simvolokov
authors.forename: A V
authors.initials: AV
authors.lastname: Nikitin
authors.forename: L G
authors.initials: LG
authors.lastname: Iakovleva
mesh_terms: D000208:Acute Disease; D000276:Adjuvants, Immunologic / Q000276:immunology; D000328:Adult; D000368:Aged; D002734:Chlorophyll / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004338:Drug Combinations / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007958:Leukocyte Count / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000627:therapeutic use*; D011018:Pneumonia, Pneumococcal / Q000188:drug therapy* / Q000276:immunology; D011023:Pneumonia, Staphylococcal / Q000188:drug therapy* / Q000276:immunology; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology
chemical_list: D000276:Adjuvants, Immunologic; D004338:Drug Combinations; D007136:Immunoglobulins; D010936:Plant Extracts; C002969:chlorophyllypt; D002734:Chlorophyll
vernacular_title: Kliniko-immunologicheskaia éffektivnost' khlorofillipta pri lechenii ostroĭ destruktivnoĭ pnevmonii.