title: Diverticular disease.
abstract: Although most often clinically silent, colonic diverticula are responsible for a large number of gastrointestinal illnesses in our society. Complications of diverticular disease, including perforation and hemorrhage, may occur in 15% to 20% of patients with diverticula during their lifetime, and although often mild and self-limiting diseases, they too frequently cause life-threatening problems that require prompt surgical intervention. Despite a cadre of sophisticated laboratory and radiologic tests that have been developed to aid in the diagnosis of complicated diverticular disease, the diagnosis and treatment of diverticulitis still relies heavily on patient history, physical examination, physician judgment, and the patient's clinical response to treatment. Thus it is important for the managing physician to fully understand the pathogenesis of diverticula, the clinical consequences and modes of presentation of complicated diverticular disease, and the array of interventions available for treatment of these problems. This monograph summarizes our knowledge of diverticular disease to date and tries to give specific guidelines for the treatment of patients with complicated diverticulitis. However, it must be understood that the presentation and severity of these complications vary widely from patient to patient. Thus one cannot take a single approach toward a patient who has diverticulitis or diverticular bleeding. Rather, successful outcomes depend on an individual approach to each patient while maintaining certain generally accepted principles of treatment.
authors.affiliation: Department of Surgery, Northwestern University Medical School, Chicago, Illinois.
authors.forename: R V
authors.initials: RV
authors.lastname: Rege
authors.forename: D L
authors.initials: DL
authors.lastname: Nahrwold
mesh_terms: D003108:Colonic Diseases / Q000209:etiology / Q000628:therapy; D004239:Diverticulitis, Colonic / Q000209:etiology / Q000628:therapy; D004241:Diverticulum, Colon / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D006801:Humans; D007412:Intestinal Fistula / Q000209:etiology / Q000628:therapy