Progression of follicular large cell lymphoma to Burkitt's lymphoma.
Histologic progression of lymphoma into more aggressive cell types is well documented. We describe a patient who had the histologic and cytogenetic features of Burkitt's lymphoma after 15 years of therapy for follicular large cell lymphoma. To the best of our knowledge, this clinical progression with histologic and cytogenetic confirmation has not been reported.
Sham
R L
RL
Hematology Unit, Rochester General Hospital, New York 14642.
Phatak
P
P
Carignan
J
J
Janas
J
J
Olson
J P
JP
D002051:Burkitt Lymphoma / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D008224:Lymphoma, Follicular / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D013997:Time Factors