[Triple immunosuppression in renal transplantation in children: 3 years' experience].
Cyclosporin A in combination with low-dose steroid therapy and azathioprine was given to 50 children who received 53 renal transplants. In spite of a limited period of observation, the use of cyclosporin A, either on a post operative intravenous regime or on oral regime when primary graft function is achieved, has no significant influence on graft survival rate, which is 82% after 1 and 2 years, utilising cadaver donors. Vascular complications were responsible for the loss of 4 grafts and were associated with the use of kidneys from young donors, rather than the type of immunosuppressive agents used.
Trompeter
R S
RS
Department of Paediatric Nephrology, Royal Free Hospital, London, England.
D000293:Adolescent; D001379:Azathioprine / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003524:Cyclosporins / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006085:Graft Survival; D006801:Humans; D007223:Infant; D016030:Kidney Transplantation; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use*
D003524:Cyclosporins; D011239:Prednisolone; D001379:Azathioprine
Triple immunosuppression en transplantation rénale chez l'enfant: expérience de 3 ans.