Long-term metabolic control in recipients of segmental-pancreas grafts with pancreaticoenterostomy or duct obstruction.
Metabolic control in recipients of segmental-pancreas grafts with pancreaticoenterostomy (performed in Stockholm) or duct obstruction by polymer injection (performed in Oslo) were compared. The recipients were uremic diabetic patients and also received a kidney from the same donor. Because the patient population in the two Scandinavian countries is very similar and the immunosuppressive protocols used are almost identical, such a comparison seemed reasonable. The number of patients available for study at 1, 2, and 3 yr was 22, 10, and 4, respectively, with duct injection and 28, 10, and 3 with pancreaticoenterostomy. The mean age of the patients was somewhat higher in the Oslo series. There were no significant differences regarding immunosuppression or kidney-graft function as estimated by serum creatinine at 1, 2, and 3 yr. No significant differences were found in fasting blood glucose, glycosylated hemoglobin, and intravenous glucose tolerance between the two groups at 1, 2, and 3 yr.
Tydén
G
G
Department of Transplantation Surgery, Karolinska Institute, Huddinge Hospital, Stockholm, Sweden.
Brattström
C
C
Bolinder
J
J
Bohman
S O
SO
Groth
C G
CG
Brekke
I B
IB
Holdaas
H
H
Flatmark
A
A
D000328:Adult; D003404:Creatinine / Q000097:blood; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology / Q000601:surgery*; D004766:Enterostomy; D005500:Follow-Up Studies; D006801:Humans; D007165:Immunosuppression Therapy; D016030:Kidney Transplantation; D008722:Methods; D008875:Middle Aged; D016035:Pancreas Transplantation; D010183:Pancreatic Ducts
D003404:Creatinine