Time course of lipolytic activity and lipid peroxidation after whole-body gamma irradiation of rats.
The content of fluorescing products of lipid peroxidation (LFP) and hormone-stimulated lipolytic activity were determined in rat epididymal adipose tissue during a 29-day interval after whole-body gamma irradiation. An increase in LFP was accompanied by a decrease in lipolytic activity. It is suggested that these effects are interrelated and that the decrease in lipolysis in irradiated, semi fasting rats is an additional deteriorating factor leading to death in some animals.
Rejholcová
M
M
Laboratory for Endocrinology and Metabolism, Faculty of Medicine, Charles University, Praha, Czechoslovakia.
Wilhelm
J
J
D000818:Animals; D003037:Cobalt Radioisotopes; D005720:Gamma Rays; D015227:Lipid Peroxidation / Q000528:radiation effects*; D008066:Lipolysis / Q000528:radiation effects*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors; D014916:Whole-Body Irradiation
D003037:Cobalt Radioisotopes