Effect of a desensitizing dentifrice on dentinal hypersensitivity.
The objective of this study was to assess the effectiveness of a dentifrice with 2% dibasic sodium citrate in poloxamer 407 in decreasing dentinal hypersensitivity. The test toothpaste was compared with a control toothpaste containing 0.76% sodium monofluorophosphate in a 6-week double-blind clinical trial. A total of 75 hypersensitive teeth were examined in the test group, while 100 hypersensitive teeth were in the control group. Changes in hypersensitivity levels were monitored after 6 weeks, using thermal, chemical and mechanical stimuli. At the end of 6 weeks, the test dentifrice was not significantly more effective than the control in decreasing dentinal hypersensitivity. Of the stimuli used, cold was the most effective in eliciting a hypersensitive response, followed by chemical stimulation and air. Heat and toothbrushing caused the least discomfort.
Ong
G
G
Strahan
J D
JD
D000328:Adult; D002951:Citrates / Q000627:therapeutic use*; D019343:Citric Acid; D003080:Cold Temperature; D003802:Dentifrices / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D013501:Surface-Active Agents; D014100:Toothpastes / Q000627:therapeutic use*
D002951:Citrates; D003802:Dentifrices; D013501:Surface-Active Agents; D014100:Toothpastes; D019343:Citric Acid