title: Invasive histoplasmosis of the mandible.
abstract: We present a case of an 82-year-old man with a 1-year history of a slowly enlarging, nontender, exophytic oral mucosal lesion with focal ulceration of the right alveolar ridge of the mandible associated with cortical bone resorption. Two consecutive biopsies revealed histoplasma capsulatum. A review of the literature confirms that this is an uncommon manifestation of this fungal disease, but must be considered in the differential diagnosis of an oral ulcerative lesion.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Chicago Medical Center, Illinois.
authors.forename: T J
authors.initials: TJ
authors.lastname: Dobleman
authors.forename: N
authors.initials: N
authors.lastname: Scher
authors.forename: M
authors.initials: M
authors.lastname: Goldman
authors.forename: S
authors.initials: S
authors.lastname: Doot
mesh_terms: D000368:Aged; D001706:Biopsy; D003937:Diagnosis, Differential; D006660:Histoplasmosis / Q000473:pathology*; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000473:pathology*