title: Emergency surgical revascularization following coronary angioplasty: evaluation of operative results by isoenzyme analysis and electrocardiography.
abstract: Seventeen patients underwent emergency coronary artery bypass grafting due to balloon catheter induced occlusion or dissection of a major coronary artery. Patients were revascularized within a maximum of 210 min from the onset of ischaemia and received an average of 1.6 distal anastomoses. A perioperative transmural or non-transmural myocardial infarction as diagnosed by CK-MB activity and electrocardiographic patterns occurred in 7 patients (41.2%). One early death resulted in an overall perioperative mortality of 5.9%. Successful preservation of myocardium was demonstrated in 10 patients by a rapid decline of CK-MB activity, no perioperative electrocardiographic changes and no requirement for inotropic support. The incidence of a perioperative myocardial infarction was independent of the anginal status before coronary angioplasty or the angiographic evidence of a complete occlusion versus a dissection. Major ischaemic myocardial complications associated with coronary angioplasty are rare but frequently catastrophic events. Fast surgical intervention is mandatory to prevent myocardial infarction or to limit the extent of injury. The operative outcome can be evaluated by careful analysis of time release curves and cumulative parameters of CK-MB activity.
authors.affiliation: Division of Cardiothoracic and Vascular Surgery, Johannes Gutenberg University, Mainz, FRG.
authors.forename: U
authors.initials: U
authors.lastname: Hake
authors.forename: S
authors.initials: S
authors.lastname: Iversen
authors.forename: H G
authors.initials: HG
authors.lastname: Jakob
authors.forename: A
authors.initials: A
authors.lastname: Neufang
authors.forename: R
authors.initials: R
authors.lastname: Erbel
authors.forename: T
authors.initials: T
authors.lastname: Pop
authors.forename: J
authors.initials: J
authors.lastname: Meyer
authors.forename: H
authors.initials: H
authors.lastname: Oelert
mesh_terms: D000328:Adult; D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D001026:Coronary Artery Bypass / Q000401:mortality*; D003327:Coronary Disease / Q000150:complications / Q000209:etiology / Q000601:surgery*; D003402:Creatine Kinase / Q000097:blood*; D004562:Electrocardiography; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007527:Isoenzymes; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000209:etiology / Q000503:physiopathology; D011183:Postoperative Complications / Q000097:blood* / Q000209:etiology / Q000503:physiopathology
chemical_list: D007527:Isoenzymes; D003402:Creatine Kinase