Cutaneous gangrene, vascular calcification, and hyperparathyroidism.
We describe the development of necrotic ulcers with underlying vascular calcification in a 72-year-old man who had chronic renal failure. These lesions had surrounding ecchymoses. The patient had a normal serum calcium concentration, an elevated parathyroid hormone level, and findings consistent with a parathyroid adenoma on ultrasonography. We consider this another case of a characteristic cutaneous syndrome secondary to underlying vascular calcification and hyperparathyroidism.
Mehregan
D A
DA
Department of Dermatology, Mayo Clinic, Rochester, MN 55905.
Winkelmann
R K
RK
D000368:Aged; D002114:Calcinosis / Q000150:complications*; D005734:Gangrene; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications*; D007871:Leg Ulcer / Q000209:etiology* / Q000473:pathology; D008297:Male; D014652:Vascular Diseases / Q000150:complications*