title: Prepubertal diagnosis of Klinefelter syndrome in a patient with taurodontic teeth.
abstract: A 9-year, 10-month-old male presented for dental treatment planning for multiple missing permanent teeth. Panoramic radiographs revealed taurodontic permanent first molars and primary second molars. The patient was of slim build with a long lower body and moderately long fingers. Because of the presence of taurodontic teeth, chromosomal analysis was done and revealed 47,XXY - Klinefelter syndrome. Patients with meso- or hypertaurodontic teeth who do not have a syndrome known to be associated with taurodontic teeth should be considered for chromosome analysis because of the high association of taurodontic teeth with X-chromosome aneuploidy syndromes.
authors.forename: P A
authors.initials: PA
authors.lastname: Darbyshire
authors.forename: C J
authors.initials: CJ
authors.lastname: Witkop
authors.forename: J
authors.initials: J
authors.lastname: Cervenka
mesh_terms: D000848:Anodontia; D002648:Child; D006801:Humans; D007713:Klinefelter Syndrome / Q000175:diagnosis*; D008297:Male; D014071:Tooth Abnormalities