title: Periodontal manifestations of adult onset of histiocytosis X.
abstract: Histiocytosis X, a reticuloendothelial disorder, includes the three clinical syndromes: Letterer-Siwe and Hand-Schuller-Christian diseases and eosinophilic granuloma of the bone. Twenty-eight cases of adult onset of histiocytosis X involving the head and neck region were found in the literature during the past 20 years; 15 cases were confined to this area, out of which 13 involved jaw bones. Characteristic signs and symptoms of periodontal disease were observed in 22 out of 28 cases (79%) with the lower molar area as a predominant site. A case report of a non-osseous chronic disseminated histiocytosis X with periodontal involvement is presented. The importance of histiocytosis X, as an entity that should be kept in mind as a differential diagnosis of a process where destructive periodontitis is involved, is discussed.
authors.affiliation: Section of Periodontology, Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Israel.
authors.forename: Z
authors.initials: Z
authors.lastname: Artzi
authors.forename: M
authors.initials: M
authors.lastname: Grosky
authors.forename: M
authors.initials: M
authors.lastname: Raviv
mesh_terms: D000328:Adult; D004487:Edema / Q000209:etiology; D004803:Eosinophilic Granuloma / Q000209:etiology* / Q000473:pathology; D005882:Gingival Diseases / Q000209:etiology* / Q000473:pathology; D005891:Gingivitis / Q000209:etiology; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male