title: Pattern electroretinogram in glaucoma and ocular hypertension.
abstract: We recorded the pattern electroretinogram (PERG) to small (0.8 degree) and very large (15 degrees) check sizes in normal subjects, in patients with early-stage glaucoma, and in patients with ocular hypertension. In glaucoma, the PERG amplitude was reduced. This reduction was more prominent for a check size of 0.8 degree as compared with 15 degrees stimuli and for high (16/s) as compared with low (7.8/s) reversal rates. Using a discriminant analysis of the amplitudes for two different check sizes, we could distinguish the normal and the glaucoma groups with a specificity of 96% and a sensitivity of 91%. Of the ocular hypertension patients, 43% were classified as pathologic by the discriminant analysis. Thus multivariate analysis of the PERG may increase its diagnostic value.
authors.affiliation: Universität-Augenklinik, Freiburg, FRG.
authors.forename: M
authors.initials: M
authors.lastname: Bach
authors.forename: A
authors.initials: A
authors.lastname: Speidel-Fiaux
mesh_terms: D000328:Adult; D000368:Aged; D004596:Electroretinography; D005556:Form Perception; D005901:Glaucoma / Q000175:diagnosis*; D006801:Humans; D008875:Middle Aged; D015999:Multivariate Analysis; D009798:Ocular Hypertension / Q000175:diagnosis*; D010364:Pattern Recognition, Visual