[Transplantation of the bone marrow after total body irradiation of the victims after the accident at the Chernobyl atomic power plant].
Bone marrow transplantation was carried out in 13 patients. Seven patients (the doses of the total gamma-radiation were from 6.6 to 11.9 Gy; 4 identical, 2 "haplo + I", 1 haploidentical to BMT) died from radiation-induced skin injuries (beta-burns) incompatible with further life, from intestinal and pulmonary lesions from days 17 to 25 after radiation (days +2-+9 after BMT). Four patients (the doses were from 4.4 to 10.2 Gy; 2 identical, 1 "haplo + I", 1 haploidentical to BMT) died from acute secondary disease (ASD) and herpes virus infections within 34 (+27) to 91 (+79) days. Two patients (the doses constituted 5.6 and 8.7 Gy; haploidentical to BMT) are alive. They demonstrated incomplete myelopoietic chimera (up to +32-+36 days), non-grave ASD (from day +13 to day +57), the onset of the own myelopoiesis on days 27-28 and its final recovery by the termination of the 3d-4th month following radiation.
Baranov
A E
AE
Geĭl
R P
RP
Gus'kova
A K
AK
Piatkin
E K
EK
Chemplin
R
R
D000059:Accidents; D016026:Bone Marrow Transplantation; D006410:Hematopoiesis / Q000528:radiation effects; D006801:Humans; D009688:Nuclear Reactors; D011210:Power Plants; D011829:Radiation Dosage; D011832:Radiation Injuries / Q000097:blood / Q000209:etiology / Q000601:surgery*; D011847:Radioactive Fallout / Q000009:adverse effects*; D013997:Time Factors; D014455:Ukraine; D014916:Whole-Body Irradiation
D011847:Radioactive Fallout
Transplantatsiia kostnogo mozga posle obshchego oblucheniia u postradavshikh pri avarii na Chernobyl'skoĭ AES.