Corticosteroids for the management of ulcerative colitis and Crohn's disease.
Corticosteroids are of proven value for the treatment of active ulcerative colitis and Crohn's disease, but are of little value for the maintenance of remission. The development of new steroid compounds with low systemic bioavailability should allow higher doses to be given for longer periods without risking serious adverse reactions.
Jewell
D P
DP
Gastroenterology Unit, Radcliffe Infirmary, Oxford.
D000287:Administration, Topical; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D003424:Crohn Disease / Q000188:drug therapy*; D004334:Drug Administration Schedule; D004733:Enema; D006801:Humans
D000305:Adrenal Cortex Hormones