title: Clinical pharmacology of chronic orofacial pain medications.
abstract: Pharmacologic intervention with nontraditional analgesics such as antidepressants, anticonvulsants, and ergot alkaloids, is often useful in the management of chronic pain disorders, including those in the orofacial region. The side effects of these drugs are different and often more severe than the analgesics commonly prescribed in dental practices and their prescription by those without advanced training in the area of chronic pain management is not recommended. This article will review the mechanism of action, efficacy, and toxicity of some of the more commonly prescribed chronic pain medications.
authors.forename: R E
authors.initials: RE
authors.lastname: Paul
authors.forename: E V
authors.initials: EV
authors.lastname: Hersh
mesh_terms: D000700:Analgesics; D000927:Anticonvulsants / Q000494:pharmacology*; D000929:Antidepressive Agents, Tricyclic / Q000494:pharmacology*; D002908:Chronic Disease; D004876:Ergot Alkaloids / Q000494:pharmacology*; D005157:Facial Pain / Q000188:drug therapy*; D006801:Humans; D008881:Migraine Disorders
chemical_list: D000700:Analgesics; D000927:Anticonvulsants; D000929:Antidepressive Agents, Tricyclic; D004876:Ergot Alkaloids