Modified osmotic fragility test for the laboratory diagnosis of hereditary spherocytosis.
A modified osmotic fragility test, based on measurement of hemolysis in four hypotonic NaCl solutions and logarithmic linearization of osmotic fragility curve is, like the "Pink test," a specific and sensitive test for the laboratory diagnosis of hereditary spherocytosis.
Judkiewicz
L
L
Institute of Pathology, Medical Academy of Lodz, Poland.
Bartosz
G
G
Oplatowska
A
A
Szczepanek
A
A
D004912:Erythrocytes / Q000378:metabolism; D006403:Hematologic Tests / Q000379:methods* / Q000592:standards; D006461:Hemolysis; D006801:Humans; D009996:Osmotic Fragility; D012680:Sensitivity and Specificity; D013103:Spherocytosis, Hereditary / Q000097:blood / Q000175:diagnosis*