title: Intercostal blockade and pulmonary function after cholecystectomy.
abstract: Sixty-six patients undergoing cholecystectomy were randomly allocated to receive either intercostal blockade with bupivacaine supplemented with papaveretum or papaveretum alone for postoperative analgesia. Both groups were similar regarding distribution of sex, age, and weight. These two groups were compared. Patients who did not have intercostal blockade required postoperative analgesia sooner. There was no significant difference, however, in the total consumption of papaveretum. Both groups experienced similar degrees of pain, and there were no differences in postoperative pulmonary function. We conclude that although single intercostal blockade is an effective analgesic, it does not improve pain relief and does not improve pulmonary function after cholecystectomy when compared with a regimen of on-demand, intramuscularly administered papaveretum.
authors.affiliation: Department of Surgery, Derbyshire Royal Infirmary, England.
authors.forename: W B
authors.initials: WB
authors.lastname: Ross
authors.forename: J H
authors.initials: JH
authors.lastname: Tweedie
authors.forename: Y P
authors.initials: YP
authors.lastname: Leong
authors.forename: A
authors.initials: A
authors.lastname: Wyman
authors.forename: B M
authors.initials: BM
authors.lastname: Smithers
mesh_terms: D000698:Analgesia; D002763:Cholecystectomy; D002986:Clinical Trials as Topic; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D007367:Intercostal Nerves; D008297:Male; D008875:Middle Aged; D009407:Nerve Block; D009892:Opium / Q000008:administration & dosage; D010149:Postoperative Pain / Q000628:therapy*; D010366:Peak Expiratory Flow Rate; D011183:Postoperative Complications; D011446:Prospective Studies; D011897:Random Allocation; D012129:Respiratory Function Tests; D013900:Thoracic Nerves; D014797:Vital Capacity
chemical_list: D009892:Opium