title: Evolution in antibiotic susceptibility of Bacteroides fragilis group strains in France based on periodic surveys.
abstract: Anaerobic antibiotic susceptibility testing with standardized methods enabled the authors to speculate on the evolution of antibiotic resistance within the Bacteroides fragilis group strains. Cefoxitin resistance was stable (0-5%) until 1985 and gradually increased later. Clindamycin resistance emerged in 1980 with a stable 10% resistance rate until 1986. An increase in clindamycin resistance developed in three institutions in 1987. No change was detected for imipenem and metronidazole, while piperacillin resistance increased since 1986. A comparison of antibiotic resistance rates is discussed for anaerobes in different countries.
authors.affiliation: Department of Microbiology, Faculty of Pharmacy, University Lille II.
authors.forename: L
authors.initials: L
authors.lastname: Dubreuil
authors.forename: M
authors.initials: M
authors.lastname: Derriennic
authors.forename: A
authors.initials: A
authors.lastname: Sedallian
authors.forename: C
authors.initials: C
authors.lastname: Romond
authors.forename: A L
authors.initials: AL
authors.lastname: Courtieu
mesh_terms: D001439:Bacteroides / Q000187:drug effects* / Q000254:growth & development; D002440:Cefoxitin / Q000494:pharmacology*; D002981:Clindamycin / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D005602:France; D006801:Humans; D008795:Metronidazole / Q000494:pharmacology*
chemical_list: D008795:Metronidazole; D002981:Clindamycin; D002440:Cefoxitin