title: Androgen influence on exocrine pancreatic cancer.
abstract: Since the discovery of the first gastrointestinal hormones it has been intriguing to think that these defined chemical messengers may also influence the growth of tumors. Today, treatment with sex-hormones is well documented--and used in clinical practice--in prostatic (1,2), breast (3), endometrial, and ovarian carcinoma (4). Hormonal therapy (progesterone) has also been tried with some success in renal carcinoma (5,6). Nevertheless, cancers of the gastrointestinal tract--colorectal, liver, stomach, and pancreatic, carcinoma, which constitute 25 percent of all malignancies in Scandinavia--are only treated by other means, mainly surgery, although there is substantial evidence today that these tumors can also be influenced by hormones.
authors.affiliation: Department of Surgery, Lund University, Sweden.
authors.forename: A
authors.initials: A
authors.lastname: Andrén-Sandberg
mesh_terms: D000728:Androgens / Q000502:physiology*; D000818:Animals; D005260:Female; D006801:Humans; D008297:Male; D010190:Pancreatic Neoplasms / Q000503:physiopathology*; D012737:Sex Factors; D013739:Testosterone / Q000502:physiology*
chemical_list: D000728:Androgens; D013739:Testosterone