Comparison of Escherichia coli K-12 outer membrane protease OmpT and Salmonella typhimurium E protein.
The predicted amino acid sequence of OmpT, an Escherichia coli outer membrane protease, was found to be highly homologous to that predicted for the pgtE gene product of Salmonella typhimurium. In this paper, it is shown that pgtE codes for a protein functionally homologous to OmpT as judged by its ability to proteolyze T7 RNA polymerase and to localize in the outer membrane of E. coli.
Grodberg
J
J
Department of Microbiology, State University of New York, Stony Brook 11794.
Dunn
J J
JJ
D000595:Amino Acid Sequence; D001425:Bacterial Outer Membrane Proteins / Q000378:metabolism*; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism; D004926:Escherichia coli / Q000201:enzymology*; D008969:Molecular Sequence Data; D008970:Molecular Weight; D010447:Peptide Hydrolases / Q000378:metabolism*; D011498:Protein Precursors / Q000378:metabolism; D011994:Recombinant Proteins / Q000378:metabolism; D012486:Salmonella typhimurium / Q000201:enzymology*
D001425:Bacterial Outer Membrane Proteins; D011498:Protein Precursors; D011994:Recombinant Proteins; D012321:DNA-Directed RNA Polymerases; D010447:Peptide Hydrolases