title: [Diagnosis of very early arteriosclerosis vascular changes using Duplex sonography].
abstract: The technical evolution of ultrasonic equipment provides a high resolution imaging analysis of the vessel wall and thereby offers new possibilities in diagnosing very early atherosclerotic changes. The typical B-mode image in human and animal arteries shows parallel wall contures enclosing a hypoechoic space. In this study in Vitro- and in Vivo-experiments in rabbit aortas document the distance between these contures correlating histologically with a high cholesterol diet caused a broadening of the hypoechoic space in the rabbit aortic vessel wall. The data demonstrate that high resolution Duplex Sonography is a usefull noninvasive approach for the detection of very early atherosclerotic changes in arterial vessel walls in a stage before plaques can be identified.
authors.affiliation: Medizinische Poliklinik, Universität Bonn.
authors.forename: M
authors.initials: M
authors.lastname: Ludwig
authors.forename: K
authors.initials: K
authors.lastname: Kraft
authors.forename: W
authors.initials: W
authors.lastname: Rücker
authors.forename: A M
authors.initials: AM
authors.lastname: Hüther
mesh_terms: D000818:Animals; D001011:Aorta / Q000473:pathology; D001161:Arteriosclerosis / Q000175:diagnosis*; D004036:Diet, Atherogenic; D004730:Endothelium, Vascular / Q000473:pathology; D009131:Muscle, Smooth, Vascular / Q000473:pathology; D011817:Rabbits; D014463:Ultrasonography
vernacular_title: Die Diagnose sehr früher arteriosklerotischer Gefässwandveränderungen mit Hilfe der Duplexsonographie.