title: Total hip replacement in the renal transplant recipient.
abstract: Osteonecrosis of the femoral head is a severely disabling complication of steroid immunosuppression in renal transplant patients. We report 31 total hip arthroplasties in 21 renal transplant recipients with an average follow-up of six years. There were no problems with wound healing or infection despite full immunosuppression. Four hips developed symptomatic loosening but the other results were excellent, comparing well with other methods of treatment for osteonecrosis. Ten patients died during the follow-up period. Total hip replacement is a safe and effective treatment for transplant recipients and, in view of their limited life expectancy, should be considered at an early stage in their treatment.
authors.affiliation: Orthopaedic Research Unit, Addenbrooke's Hospital, Cambridge, England.
authors.forename: P J
authors.initials: PJ
authors.lastname: Radford
authors.forename: A
authors.initials: A
authors.lastname: Doran
authors.forename: R A
authors.initials: RA
authors.lastname: Greatorex
authors.forename: N
authors.initials: N
authors.lastname: Rushton
mesh_terms: D000368:Aged; D005260:Female; D005271:Femur Head Necrosis / Q000139:chemically induced / Q000601:surgery*; D006622:Hip Prosthesis; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D007676:Kidney Failure, Chronic / Q000150:complications / Q000601:surgery*; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D010027:Osteotomy; D011183:Postoperative Complications; D012189:Retrospective Studies
chemical_list: D007166:Immunosuppressive Agents