[Mechanisms of the pulmonary congestion in ligature strangulation (VIII)].
The authors observed the localization of adrenaline, noradrenaline and histamine in the walls of splenic and renal blood vessels of ligature strangulated guinea-pigs by autoradiography and immunocytochemistry, and measured the 3H-adrenaline and 3H-noradrenaline contents of the spleen et al.'s tissues of the guinea-pigs sacrificed by ligature strangulation. In both the experimental and control groups, some silver grains were observed in the endothelial cells of splenic central arteries, splenic trabecular veins, splenic venous sinuses and renal interlobular arteries after 3H-adrenaline administrations. In the ligature strangulation, the reactions of histamine exclusively demonstrated in the Weibel-Palade bodies of the splenic central arterial endothelial cells. By radioassay, the 3H-adrenaline contents of splenic and renal tissues were more than the control groups. From the above-mentioned facts, adrenaline-induced constrictions of splenic central arteries, splenic trabecular veins and splenic venous sinuses were recognized.
Kita
T
T
Furuya
Y
Y
D000402:Airway Obstruction / Q000150:complications*; D000818:Animals; D004837:Epinephrine / Q000378:metabolism; D006168:Guinea Pigs; D006632:Histamine / Q000378:metabolism; D007668:Kidney / Q000098:blood supply / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D008297:Male; D009638:Norepinephrine / Q000378:metabolism; D011654:Pulmonary Edema / Q000209:etiology* / Q000503:physiopathology; D013154:Spleen / Q000098:blood supply / Q000378:metabolism
D006632:Histamine; D009638:Norepinephrine; D004837:Epinephrine