[Ultraimmunocytochemical diagnosis of squamous cell cancer of the digestive tract].
Procedure using fluorescent and peroxidase labeling and monoclonal antibodies to basal-cell antigen of multilayer epithelium showed the antigen to occur in squamous cell cancer irrespective of site and degree of cell differentiation; this, however, was not the case with tumors of other origins. Ultraimmunocytochemical method was used to identify localization of the antigen at cellular and subcellular levels, namely, in tonofilaments and desmosomes. Said situation is considered to suggest squamous cell carcinoma.
Silagadze
D G
DG
Beletskaia
L V
LV
Chelidze
P V
PV
Drobyshevskaia
E I
EI
Gabuniia
U A
UA
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm / Q000032:analysis; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000648:ultrastructure; D004067:Digestive System Neoplasms / Q000175:diagnosis* / Q000648:ultrastructure; D004848:Epithelium / Q000276:immunology / Q000648:ultrastructure; D005455:Fluorescent Antibody Technique; D006801:Humans; D007124:Immunoenzyme Techniques; D007150:Immunohistochemistry; D008854:Microscopy, Electron
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm
Ul'traimmunotsitokhimicheskaia diagnostika ploskokletochnogo raka pishchevaritel'nogo trakta.