Genes coding for Shiga-like toxin and heat-stabile enterotoxin in porcine strains of Escherichia coli.
Besides diarrheagenic enterotoxigenic Escherichia coli (ETEC) that produce classical heat stable and/or heat labile enterotoxins (STs, LTs) and the class of Shiga-like toxin-producing entero-hemorrhagic E. coli (EHEC), a new category of E. coli is defined sharing similarities with ETEC and EHEC. DNA hybridization studies indicate that some E. coli serovars from porcine origin harbor genes encoding cytotonic ST and cytotoxic Shiga-like toxin. The presence of two potent toxins might contribute to the virulence of such strains and should be taken into consideration when bio-assays are performed.
Meyer
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Institut für Medizinische Mikrobiologie und Immunologie, Universität Hamburg, F.R.G.
Karch
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D000818:Animals; D001427:Bacterial Toxins / Q000235:genetics*; D004768:Enterotoxins / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics / Q000472:pathogenicity*; D029968:Escherichia coli Proteins; D009693:Nucleic Acid Hybridization; D022622:Shiga Toxin 1; D022641:Shiga Toxin 2; D013552:Swine / Q000382:microbiology*; D014774:Virulence
D001427:Bacterial Toxins; D004768:Enterotoxins; D029968:Escherichia coli Proteins; D022622:Shiga Toxin 1; D022641:Shiga Toxin 2; C027538:heat-labile enterotoxin, E coli