[Changes in the metabolism of a pyrido(1,2 a)pyrimidine derivative, CH-150, under the effects of 3-methylcholanthrene and phenobarbital in microsome fractions in rats, studied by liver perfusion method].
Jemnitz
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K
Dénes
G
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Vargay
Z
Z
Hermecz
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I
D000818:Animals; D001711:Biotransformation; D002250:Carbon Radioisotopes; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008748:Methylcholanthrene / Q000494:pharmacology*; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D010477:Perfusion; D010634:Phenobarbital / Q000494:pharmacology*; D011743:Pyrimidines / Q000378:metabolism* / Q000494:pharmacology; D011744:Pyrimidinones / Q000378:metabolism* / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains
D002250:Carbon Radioisotopes; D011743:Pyrimidines; D011744:Pyrimidinones; D008748:Methylcholanthrene; C045845:CH 150; D010634:Phenobarbital
Egy pirido [1,2 a]pirimidin származék, a CH-150 metaboliz-musának változása 3-metilkolantrén és fenobarbitál hatására mikroszóma frakcióban és izolált májperfúziós módszerrel, patkányban.