[Diagnosis of very early arteriosclerosis vascular changes using Duplex sonography].
The technical evolution of ultrasonic equipment provides a high resolution imaging analysis of the vessel wall and thereby offers new possibilities in diagnosing very early atherosclerotic changes. The typical B-mode image in human and animal arteries shows parallel wall contures enclosing a hypoechoic space. In this study in Vitro- and in Vivo-experiments in rabbit aortas document the distance between these contures correlating histologically with a high cholesterol diet caused a broadening of the hypoechoic space in the rabbit aortic vessel wall. The data demonstrate that high resolution Duplex Sonography is a usefull noninvasive approach for the detection of very early atherosclerotic changes in arterial vessel walls in a stage before plaques can be identified.
Ludwig
M
M
Medizinische Poliklinik, Universität Bonn.
Kraft
K
K
Rücker
W
W
Hüther
A M
AM
D000818:Animals; D001011:Aorta / Q000473:pathology; D001161:Arteriosclerosis / Q000175:diagnosis*; D004036:Diet, Atherogenic; D004730:Endothelium, Vascular / Q000473:pathology; D009131:Muscle, Smooth, Vascular / Q000473:pathology; D011817:Rabbits; D014463:Ultrasonography
Die Diagnose sehr früher arteriosklerotischer Gefässwandveränderungen mit Hilfe der Duplexsonographie.