Late relapses in acute lymphoblastic leukemia.
Two children presented with relapsed acute lymphoblastic leukemia 6 years and 8 years after cessation of maintenance treatment. Relapses this length of time off treatment are unusual, with only 7 previously reported cases. It is often unclear whether the relapse is of the original disease or a second leukemia, and our results in both cases suggest relapse of their primary disease.
Russell
L
L
Department of Haematology, Royal Hospital for Sick Children, Edinburgh, Scotland.
Eden
O B
OB
D000293:Adolescent; D005260:Female; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000473:pathology*; D013997:Time Factors