title: Ceftriaxone in chemoprophylaxis and therapy of urinary tract infections.
abstract: We analysed eight prospective randomized trials describing the use of ceftriaxone (Rocephin) in short-term prophylaxis in patients undergoing urologic surgery. The results of these trials show that chemoprophylaxis with ceftriaxone is effective. In the therapy of postoperative infections in urologic surgery the single daily dose of ceftriaxone represents a considerable advantage both regarding patients' compliance and clinical convenience. From March 1987 to January 1988, 25 patients with postoperative infections after urologic surgery were treated with ceftriaxone 1 g i.m. once daily. Quick resolution of signs and symptoms of infection occurred in all cases.
authors.affiliation: Clinica Urologica I dell'Università di Milano, Italia.
authors.forename: E
authors.initials: E
authors.lastname: Pisani
authors.forename: S
authors.initials: S
authors.lastname: Dell'Acqua
authors.forename: D
authors.initials: D
authors.lastname: Morosini
authors.forename: A
authors.initials: A
authors.lastname: Mandressi
authors.forename: A
authors.initials: A
authors.lastname: Trinchieri
mesh_terms: D001424:Bacterial Infections / Q000188:drug therapy / Q000517:prevention & control; D002443:Ceftriaxone / Q000627:therapeutic use*; D006801:Humans; D011183:Postoperative Complications / Q000517:prevention & control; D011292:Premedication; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000517:prevention & control; D014566:Urogenital System / Q000601:surgery*
chemical_list: D002443:Ceftriaxone