title: Synthesis and biological testing of certain 2-(5-substituted-2-thienylthio)benzoic acid derivatives.
abstract: The syntesis of a number of 2-(5-substituted-2-thienylthio)benzoic acid derivatives is described. The synthesized compounds were screened for their muscle relaxant and parasympatholytic activities and the results are reported.
authors.affiliation: Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura, Egypt.
authors.forename: A S
authors.initials: AS
authors.lastname: Tantawy
authors.forename: H I
authors.initials: HI
authors.lastname: el-Subbagh
authors.forename: M B
authors.initials: MB
authors.lastname: el-Ashmawy
authors.forename: A A
authors.initials: AA
authors.lastname: el-Emam
mesh_terms: D000818:Animals; D001565:Benzoates / Q000138:chemical synthesis* / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D004305:Dose-Response Relationship, Drug; D006827:Hydantoins / Q000138:chemical synthesis* / Q000494:pharmacology; D066298:In Vitro Techniques; D007422:Intestines / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D009125:Muscle Relaxants, Central / Q000138:chemical synthesis*; D009130:Muscle, Smooth / Q000187:drug effects; D010276:Parasympatholytics / Q000138:chemical synthesis*; D010862:Pilocarpine / Q000494:pharmacology; D011817:Rabbits; D012472:Salivation / Q000187:drug effects; D012545:Schiff Bases / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D001565:Benzoates; D006827:Hydantoins; D009125:Muscle Relaxants, Central; D010276:Parasympatholytics; D012545:Schiff Bases; D010862:Pilocarpine; C063961:1-(5-(carboxyphenylthio)-2-thenylideneamino)hydantoin