[Laboratory controls of heparin therapy with thrombin time, partial thromboplastin time and activated recalcification time].
For the laboratory control of a heparin therapy thrombin time, partial thromboplastin time and activated recalcification time are used. On account of distinct differences in the heparin sensitivity of these reactions an indication-related application is necessary. The ability of evidence and the possibility of establishing test-specific therapeutic regions are restricted by differences caused by reagents, individual variability and influence by accompanying haemostasiological changes. The own approach, taking into consideration the so-called heparin resistance, it presented.
Lutze
G
G
Institut für Klinische Chemie und Laboratoriumsdiagnostik, Medizinischen Akademie Magdeburg.
Presser
H J
HJ
Urbahn
H
H
D001780:Blood Coagulation Tests / Q000379:methods*; D004305:Dose-Response Relationship, Drug; D006493:Heparin / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D010314:Partial Thromboplastin Time; D013918:Thrombin Time; D014914:Whole Blood Coagulation Time
D006493:Heparin
Laborkontrollen der Heparintherapie mit der Thrombinzeit, der partiellen Thromboplastinzeit und der aktivierten Rekalzifizierungszeit.