title: Intratumoral and parametrial infusion of metronidazole in the radiotherapy of uterine cervix cancer: preliminary report.
abstract: In a recently started clinical trial, the short-term effects of radiotherapy of cervix cancer Stage IIb and III in combination with topical infusion of metronidazole solution were evaluated by determining the local clearance rate and cytologic damage in randomized and non-randomized cases. In regard to the short term effects the combined treatment was found to be superior to treatment without metronidazole.
authors.affiliation: Kazakh Research Institute of Oncology and Radiology, Alma Ata, USSR.
authors.forename: S B
authors.initials: SB
authors.lastname: Balmukhanov
authors.forename: A A
authors.initials: AA
authors.lastname: Beisebaev
authors.forename: Z I
authors.initials: ZI
authors.lastname: Aitkoolova
authors.forename: J S
authors.initials: JS
authors.lastname: Mustaphin
authors.forename: V I
authors.initials: VI
authors.lastname: Philippenko
authors.forename: R S
authors.initials: RS
authors.lastname: Rismuhamedova
authors.forename: A M
authors.initials: AM
authors.lastname: Aisarova
authors.forename: J N
authors.initials: JN
authors.lastname: Abdrahmanov
mesh_terms: D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008795:Metronidazole / Q000008:administration & dosage / Q000627:therapeutic use*; D011897:Random Allocation; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*
chemical_list: D008795:Metronidazole