title: Assessment of echographic regression criteria in ruthenium-irradiated melanoma.
abstract: Steady flattening of the tumor, increasing reflectivity and decreasing vascularity are echographic signs of successful irradiation treatment. The specific example of an irradiated choroidal melanoma shows that the absence of echographic changes by no means excludes tumor destruction. Because of a dense vitreous body hemorrhage, the melanoma could only be evaluated echographically. Since the echogram lacked evidence of regression, the tumor was locally resected 5 months later. Histology, however, revealed an amorphous mass of dead tissue pervaded by intact vessels. Apparently a successfully irradiated melanoma may generate an echo typical of vital melanoma tissue. The authors therefore draw the conclusion that only a steady tumor growth, as substantiated by an echogram, may be considered an unambiguous sign of tumor vitality.
authors.affiliation: First University Eye Clinic, Vienna, Austria.
authors.forename: R
authors.initials: R
authors.lastname: Menapace
authors.forename: W
authors.initials: W
authors.lastname: Binder
authors.forename: C
authors.initials: C
authors.lastname: Skorpik
authors.forename: H D
authors.initials: HD
authors.lastname: Gnad
mesh_terms: D002830:Choroid Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D008545:Melanoma / Q000473:pathology / Q000532:radiotherapy*; D008875:Middle Aged; D012429:Ruthenium Radioisotopes / Q000627:therapeutic use; D014463:Ultrasonography; D014823:Vitreous Hemorrhage / Q000150:complications
chemical_list: D012429:Ruthenium Radioisotopes