Immune-inflammatory response in infected arthroplasties.
We studied the immunocytology of synovial fluid in purulent endoprosthetic infections using cell subtype-specific monoclonal antibodies in avidin-biotin-peroxidase complex staining. Two thirds of the monocytes were CD15-positive, whereas CD2-positive T lymphocytes only formed one third of all the mononuclear cells. The synovial fluid monocyte-activated T-cell ratio differed from findings in sterile inflammatory, reactive and rheumatoid arthritis.
Santavirta
S
S
Orthopedic Hospital of the Invalid Foundation, Helsinki, Finland.
Konttinen
Y T
YT
Nordström
D
D
Bergroth
V
V
Antti-Poika
I
I
Eskola
A
A
D000328:Adult; D000368:Aged; D001168:Arthritis / Q000175:diagnosis / Q000209:etiology / Q000276:immunology*; D001172:Arthritis, Rheumatoid / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006622:Hip Prosthesis / Q000009:adverse effects; D006801:Humans; D007124:Immunoenzyme Techniques; D007595:Joint Prosthesis / Q000009:adverse effects; D007720:Knee Prosthesis / Q000009:adverse effects; D007963:Leukocytes, Mononuclear / Q000145:classification / Q000276:immunology; D008875:Middle Aged; D013530:Surgical Wound Infection / Q000175:diagnosis / Q000209:etiology / Q000276:immunology*; D013582:Synovial Fluid / Q000166:cytology / Q000276:immunology*