Dedifferentiated chondrosarcoma of bone.
Dedifferentiated chondrosarcoma is a highly malignant variant of chondrosarcoma. Approximately 11% of chondrosarcomas can be expected to dedifferentiate into more anaplastic lesions. Radiographic evidence of a benign-appearing cartilage lesion adjacent to a lytic, highly aggressive lesion suggests dedifferentiation. Despite radical surgical treatment, the prognosis is unfavorable, with a 5 year survival rate of 10%.
Daly
P J
PJ
Department of Orthopedics and the Section of Surgical Pathology, Rochester, Minnesota 55905.
Sim
F H
FH
Wold
L E
LE
D000368:Aged; D000708:Anaplasia / Q000473:pathology; D001859:Bone Neoplasms / Q000473:pathology*; D002813:Chondrosarcoma / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans