title: Immune-inflammatory response in infected arthroplasties.
abstract: We studied the immunocytology of synovial fluid in purulent endoprosthetic infections using cell subtype-specific monoclonal antibodies in avidin-biotin-peroxidase complex staining. Two thirds of the monocytes were CD15-positive, whereas CD2-positive T lymphocytes only formed one third of all the mononuclear cells. The synovial fluid monocyte-activated T-cell ratio differed from findings in sterile inflammatory, reactive and rheumatoid arthritis.
authors.affiliation: Orthopedic Hospital of the Invalid Foundation, Helsinki, Finland.
authors.forename: S
authors.initials: S
authors.lastname: Santavirta
authors.forename: Y T
authors.initials: YT
authors.lastname: Konttinen
authors.forename: D
authors.initials: D
authors.lastname: Nordström
authors.forename: V
authors.initials: V
authors.lastname: Bergroth
authors.forename: I
authors.initials: I
authors.lastname: Antti-Poika
authors.forename: A
authors.initials: A
authors.lastname: Eskola
mesh_terms: D000328:Adult; D000368:Aged; D001168:Arthritis / Q000175:diagnosis / Q000209:etiology / Q000276:immunology*; D001172:Arthritis, Rheumatoid / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006622:Hip Prosthesis / Q000009:adverse effects; D006801:Humans; D007124:Immunoenzyme Techniques; D007595:Joint Prosthesis / Q000009:adverse effects; D007720:Knee Prosthesis / Q000009:adverse effects; D007963:Leukocytes, Mononuclear / Q000145:classification / Q000276:immunology; D008875:Middle Aged; D013530:Surgical Wound Infection / Q000175:diagnosis / Q000209:etiology / Q000276:immunology*; D013582:Synovial Fluid / Q000166:cytology / Q000276:immunology*