title: [Multicenter research on cefoperazone efficacy and tolerance in the therapy of urinary and respiratory infections].
abstract: In this multicenter study the authors evaluated the clinical and microbiological efficacy and the local and general safety of cefoperazone sodium in 1,546 patients (946 males and 600 females, mean age 61.3 years) with lower respiratory tract (1,044) and urinary tract (539) infections. Results were very encouraging with 95.3% of clinical cures or improvement, 91.6% of microbiological eradication, and a local and general safety which was always extremely high, i.e. 96.9% and 98.3% respectively.
authors.affiliation: Università di Firenze, Istituto di Malattie Infettive.
authors.forename: F
authors.initials: F
authors.lastname: Paradisi
authors.forename: G
authors.initials: G
authors.lastname: de Crescenzo
authors.forename: M P
authors.initials: MP
authors.lastname: Ruffilli
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002438:Cefoperazone / Q000009:adverse effects / Q000627:therapeutic use*; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000382:microbiology; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D002438:Cefoperazone
vernacular_title: Indagine multicentrica sull'efficacia e sulla tollerabilità del cefoperazone nella terapia delle infezioni urinarie e respiratorie.