title: Antineutrophil cytoplasm antibodies in Kawasaki disease.
abstract: Autoantibodies against components of neutrophil cytoplasm develop during adult vasculitic diseases such as Wegener's granulomatosis and microscopic polyarteritis, and they are predominantly of the IgG class. Similar but distinct antibodies have been described in children with Kawasaki disease and both IgM and IgG class antibodies are represented. This adds another clinically distinct childhood form of vasculitis to the adult forms in which autoantibodies to neutrophil cytoplasmic antigens have been detected.
authors.affiliation: Hammersmith Hospital, London.
authors.forename: C O
authors.initials: CO
authors.lastname: Savage
authors.forename: J
authors.initials: J
authors.lastname: Tizard
authors.forename: D
authors.initials: D
authors.lastname: Jayne
authors.forename: C M
authors.initials: CM
authors.lastname: Lockwood
authors.forename: M J
authors.initials: MJ
authors.lastname: Dillon
mesh_terms: D001323:Autoantibodies / Q000032:analysis / Q000276:immunology; D002675:Child, Preschool; D003593:Cytoplasm / Q000276:immunology; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis* / Q000276:immunology; D007075:Immunoglobulin M / Q000032:analysis* / Q000276:immunology; D007223:Infant; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000276:immunology*; D009504:Neutrophils / Q000276:immunology*; D011863:Radioimmunoassay
chemical_list: D001323:Autoantibodies; D007074:Immunoglobulin G; D007075:Immunoglobulin M