Solar-ultraviolet-induced damage to DNA.
Literature on the biological (mutagenesis) and molecular (DNA lesions and their cellular processing) events resulting from exposure of cells to solar ultraviolet and visible radiations is discussed. The problems encountered with research in this area are presented. Our sparse understanding of the complex mixture of events caused in cells by solar radiation and the mechanisms subserving these events is outlined.
Peak
M J
MJ
Biological, Environmental, and Medical Research Division, Argonne National Laboratory, Illinois.
Peak
J G
JG
D004249:DNA Damage; D004269:DNA, Bacterial / Q000528:radiation effects; D009154:Mutation; D011740:Pyrimidine Dimers / Q000378:metabolism; D011743:Pyrimidines / Q000528:radiation effects; D013472:Sunlight / Q000009:adverse effects*; D014466:Ultraviolet Rays / Q000009:adverse effects*
D004269:DNA, Bacterial; D011740:Pyrimidine Dimers; D011743:Pyrimidines