title: The Uganda I/CDC strain of Plasmodium malariae in Saimiri sciureus boliviensis.
abstract: The Uganda I/CDC strain of Plasmodium malariae, initially adapted to monkeys of the genus Aotus, was studied in splenectomized Saimiri sciureus boliviensis. Mean maximum parasitemia ranged from 248 to 22,134/mm3. Only 1 mosquito was infected of 2,238 examined. After the parasite was adapted to this host, infections were characterized by periods of detectable parasitemia extending up to 269 days and by sustained periods when parasite counts were greater than 1,000/mm3. After 4 linear passages, the developmental time required before the primary peak parasite count was approximately 2 mo.
authors.affiliation: Division of Parasitic Diseases, Centers for Disease Control, Atlanta, Georgia 30333.
authors.forename: W E
authors.initials: WE
authors.lastname: Collins
authors.forename: J C
authors.initials: JC
authors.lastname: Skinner
authors.forename: J R
authors.initials: JR
authors.lastname: Broderson
authors.forename: B B
authors.initials: BB
authors.lastname: Richardson
authors.forename: P S
authors.initials: PS
authors.lastname: Stanfill
mesh_terms: D000818:Animals; D000852:Anopheles / Q000469:parasitology; D002427:Cebidae / Q000469:parasitology*; D004195:Disease Models, Animal; D008288:Malaria / Q000469:parasitology* / Q000635:transmission; D010965:Plasmodium malariae / Q000254:growth & development* / Q000302:isolation & purification; D012453:Saimiri / Q000469:parasitology*; D013156:Splenectomy