title: [Monoclonal antibodies and uveal melanomas].
abstract: The authors, who have succeeded since 1976 in cultivating cells of ocular melanoma in continuous lines report the different stages for producing specific monoclonal antibodies. They particularly insist on the demonstration, through radioimmunoassay, of the specificity of marked monoclonal antibodies, on the immunohistochemical study and on biodistribution. From these data, an immunotherapy protocol has been perfected and starts being applied to human beings.
authors.forename: M J
authors.initials: MJ
authors.lastname: Le Rebeller
authors.forename: N
authors.initials: N
authors.lastname: Safi
authors.forename: S
authors.initials: S
authors.lastname: Larson
authors.forename: R
authors.initials: R
authors.lastname: Beba
authors.forename: R
authors.initials: R
authors.lastname: Kantor
authors.forename: L
authors.initials: L
authors.lastname: Donoso
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis* / Q000276:immunology; D000918:Antibody Specificity; D005260:Female; D006825:Hybridomas / Q000276:immunology / Q000378:metabolism; D007150:Immunohistochemistry; D066298:In Vitro Techniques; D008545:Melanoma / Q000276:immunology* / Q000378:metabolism; D051379:Mice; D014407:Tumor Cells, Cultured; D014604:Uveal Neoplasms / Q000276:immunology* / Q000378:metabolism
chemical_list: D000911:Antibodies, Monoclonal
vernacular_title: Anticorps monoclonaux et mélanomes uvéaux.