A test of I2t as a dose parameter for fetal weight reduction from exposure to ultrasound.
It has been suggested that fetal weight reduction by ultrasound exposure is linearly related to the dose parameter I2t, where I is the intensity and t the exposure time. A direct test of the concept was conducted using CF-1 mice. No effect on fetal weight was found at values of the dose parameter large enough to produce measurable heating in the fetal and maternal tissues.
Child
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Department of Electrical Engineering, University of Rochester, New York 14627.
Hoffman
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D
Strassner
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Carstensen
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EL
Gates
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AH
Cox
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C
Miller
M W
MW
D000818:Animals; D005260:Female; D005333:Fetus / Q000033:anatomy & histology*; D051379:Mice; D011247:Pregnancy; D014463:Ultrasonography / Q000009:adverse effects*; D015431:Weight Loss