Dermatomyositis and malignancy.
In summary, it can be stated that: 1. Dermatomyositis is probably associated with an increased incidence of malignancy. 2. Tumor types found seem to roughly approximate the frequencies of those found in the general population. 3. If present, the malignancy can precede, occur concurrently with, or follow the diagnosis of dermatomyositis. 4. Treatment of associated malignancy may or may not have an effect on myositic or cutaneous disease. 5. Dermatomyositis and associated malignancy may share a common pathogenesis resulting from abnormal immune function. 6. Search for malignancy should be carried out on the basis of abnormal findings on history and physical examination or screening laboratory.
Richardson
J B
JB
Department of Medicine, University of Louisville School of Medicine, Kentucky.
Callen
J P
JP
D003882:Dermatomyositis / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D009369:Neoplasms / Q000150:complications* / Q000175:diagnosis; D013997:Time Factors