[Klebocins K6 and K150: production and activity in various experimental conditions].
Klebsiella is a common agent in hospital-acquired infections and its importance in disease transmission was evident in the isolation obtained in a health center in the city of Rio Cuarto. Bacteriocinogenic strains by the cross-streak method in tryptic-soy agar were investigated. Two Klebsiella produced bacteriocins with broad patterns of sensitivity among the tested strains. The K150 klebocin was more active than the K6 klebocin, but this one was more heat-stable than K150. The klebocins were not detected in the synthetic media employed and they caused inhibitory areas in complex media, except in triptose-beef extract. K150 was not active in eosine-methylene blue and nutrient agar. The bacteriocins were associated to lipase activity and hemolytic effect on chicken erythrocytes. The strains 6 and 150 were multiresistant to antimicrobial agents, with a pattern of sensitivity different from that of other multiresistant strains.
Finola
M
M
Departamento de Microbiología e Inmunología, Facultad de Ciencias Exactas, Universidad Nacional de Río Cuarto, Argentina.
Moyano
S
S
Albesa
I
I
D001430:Bacteriocins / Q000096:biosynthesis / Q000378:metabolism*; D003470:Culture Media; D007711:Klebsiella pneumoniae / Q000378:metabolism*
D001430:Bacteriocins; D003470:Culture Media; C019447:klebocin
Klebocinas K6 y K150: producción y actividad en diferentes condiciones experimentales.