Monte Carlo simulation of DNA electrophoresis.
This paper describes an attempt to study the electrophoresis mobility of a DNA molecule in a gel by means of a Monte Carlo simulation. We find that the electrophoresis mobility mu can be well described by the empirical equation mu v kappa 1/N + kappa 2E2 with N being the number of monomers of the model chain and E being the applied field. For small E the data can merge into the linear response result mu = kappa 1/N. The paper also discusses necessary extensions of the present approach.
Batoulis
J
J
Institut für Physik, Universität Mainz, Federal Republic of Germany.
Pistoor
N
N
Kremer
K
K
Frisch
H L
HL
D003198:Computer Simulation; D004247:DNA / Q000032:analysis*; D004586:Electrophoresis / Q000379:methods; D005782:Gels; D008956:Models, Chemical; D008970:Molecular Weight
D005782:Gels; D004247:DNA