title: Freeze-fracture: a personal history.
abstract: The sequence of events leading to the development of freeze-fracture replication is described. Subsequent developments discussed include complementary replicas, replica interpretation with stereo micrograph and reversal negatives, replica reinforcement, and control of resistance evaporation.
authors.affiliation: Advanced Biotechnologies, Inc., Electron Microscopy Division, Columbia, Maryland 21046.
authors.forename: R L
authors.initials: RL
authors.lastname: Steere
mesh_terms: D001901:Botany / Q000266:history; D005614:Freeze Fracturing / Q000266:history*; D049673:History, 20th Century; D010942:Plant Viruses / Q000648:ultrastructure; D014481:United States