title: [Scintigraphy of sustained-release agar-embedded insulin suppositories].
abstract: In earlier publications [1-3] we reported on the retardation and protective effect of insulin-agar-embeddings in triglyceride suppositories by in vitro and in vivo tests on rabbits. The discovered effects were visually followed by gammascintigraphic test of adequate rectally applied 131I-insulin-specimens in the rectum and thyroid gland and, in relation with the glucose lowering course, the liberation, distribution and bioavailability of the immobilized hormone was illustrated.
authors.affiliation: Sektion Chemie der Technischen Universität Dresden.
authors.forename: G
authors.initials: G
authors.lastname: Losse
authors.forename: F
authors.initials: F
authors.lastname: Müller
authors.forename: S
authors.initials: S
authors.lastname: Fischer
authors.forename: G
authors.initials: G
authors.lastname: Wunderlich
authors.forename: E
authors.initials: E
authors.lastname: Hacker
mesh_terms: D000362:Agar; D000818:Animals; D002626:Chemistry, Pharmaceutical; D007328:Insulin / Q000008:administration & dosage* / Q000493:pharmacokinetics; D008297:Male; D011817:Rabbits; D011877:Radionuclide Imaging; D013488:Suppositories
chemical_list: D007328:Insulin; D013488:Suppositories; D000362:Agar
vernacular_title: Szintigraphische Verfolgung der retardierten Insulinliberation aus Agar-Einbettungen in Suppositorien.