title: [The mutagenicity of organic microcontamination in the environment. III. The mutagenicity of selected herbicides and insecticides in the SOS chromotest].
abstract: To determine the mutagenicity of selected herbicides and insecticides we examined 26 pure pesticide substances (polychlorinated alicyclic hydrocarbons, phenoxy fatty acids, triazines) with the help of SOS-Chromotest. We used Escherichia coli strain PQ37 in these tests without and with metabolic activation with Aroclor 1254 induced rat liver microsome fraction. None of the substances showed a provable induction of the E. coli-SOS-system, because a great number of the pesticides showed toxic effects against bacteria in high concentrations.
authors.affiliation: Institut für Hygiene und Medizinische Mikrobiologie der Fakultät für Klinische Medizin Mannheim der Ruprecht-Karls-Universität Heidelberg.
authors.forename: V
authors.initials: V
authors.lastname: Mersch-Sundermann
authors.forename: A
authors.initials: A
authors.lastname: Hofmeister
authors.forename: G
authors.initials: G
authors.lastname: Müller
authors.forename: H
authors.initials: H
authors.lastname: Hof
mesh_terms: D000818:Animals; D004260:DNA Repair / Q000187:drug effects*; D004787:Environmental Pollution; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics; D006540:Herbicides / Q000633:toxicity*; D007306:Insecticides / Q000633:toxicity*; D009152:Mutagenicity Tests; D013014:SOS Response, Genetics / Q000187:drug effects*
chemical_list: D006540:Herbicides; D007306:Insecticides
vernacular_title: Untersuchungen zur Mutagenität organischer Mikrokontaminationen in der Umwelt. III. Mitteilung: Die Mutagenität ausgewählter Herbizide und Insektizide im SOS-Chromotest.