title: Prostaglandin levels in unicameral bone cysts treated by intralesional steroid injection.
abstract: The etiology of the unicameral bone cyst remains undefined. Likewise, the treatment of the cyst has had proponents suggesting procedures ranging from decompression to diaphyseal resection. The use of intralesional steroids has gained popularity since its introduction in 1979 by Scaglietti. We present the results of aspirations of seven cysts, with serial measurements of prostaglandin levels in five cases, and suggest that the antiprostaglandin action of the steroid forms the rationale for treatment of the simple cyst.
authors.affiliation: Creighton-Nebraska Health Foundation, University of Nebraska Medical Center, Omaha.
authors.forename: R
authors.initials: R
authors.lastname: Shindell
authors.forename: W W
authors.initials: WW
authors.lastname: Huurman
authors.forename: L
authors.initials: L
authors.lastname: Lippiello
authors.forename: J F
authors.initials: JF
authors.lastname: Connolly
mesh_terms: D000293:Adolescent; D001845:Bone Cysts / Q000188:drug therapy* / Q000378:metabolism; D001842:Bone and Bones / Q000378:metabolism; D002648:Child; D003131:Combined Modality Therapy; D015232:Dinoprostone / Q000378:metabolism*; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D008775:Methylprednisolone / Q000031:analogs & derivatives*; D008776:Methylprednisolone Hemisuccinate / Q000008:administration & dosage*; D010010:Osteoclasts / Q000187:drug effects*; D013396:Suction
chemical_list: D008776:Methylprednisolone Hemisuccinate; D015232:Dinoprostone; D008775:Methylprednisolone