title: Pulmonary manifestations of the collagen vascular diseases.
abstract: The collagen vascular diseases are a heterogeneous group of immunologically mediated inflammatory disorders. The organs and tissues that compose the respiratory system are frequently affected by these diseases. Potential targets of the inflammation and injury include the lung parenchyma, tracheobronchial tree, pulmonary vasculature, pleura, larynx, and respiratory muscles. In this article, the spectrum of respiratory disease caused by systemic lupus erythematosus, rheumatoid arthritis, scleroderma, polymyositis/dermatomyositis, mixed connective tissue disease, ankylosing spondylitis, relapsing polychondritis, and Sjögren's syndrome is reviewed. Where appropriate, therapeutic options are discussed.
authors.affiliation: Department of Pulmonary Disease, Cleveland Clinic Foundation, Ohio.
authors.forename: H P
authors.initials: HP
authors.lastname: Wiedemann
authors.forename: R A
authors.initials: RA
authors.lastname: Matthay
mesh_terms: D001172:Arthritis, Rheumatoid / Q000150:complications; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology; D003095:Collagen Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008171:Lung Diseases / Q000209:etiology* / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000473:pathology; D011081:Polychondritis, Relapsing / Q000150:complications; D011877:Radionuclide Imaging; D012595:Scleroderma, Systemic / Q000150:complications; D012859:Sjogren's Syndrome / Q000150:complications / Q000000981:diagnostic imaging; D013167:Spondylitis, Ankylosing / Q000150:complications