Prolidase deficiency: a case report and literature review.
We describe a patient in whom chronic leg ulceration was due to prolidase deficiency. The clinical features of this condition are described and we discuss the metabolic abnormality and the treatment regimes which have been employed. We also report the further finding of erosive cystitis, which we consider should be added to the list of clinical features of prolidase deficiency.
Milligan
A
A
Leicester Royal Infirmary, U.K.
Graham-Brown
R A
RA
Burns
D A
DA
Anderson
I
I
D000293:Adolescent; D002908:Chronic Disease; D003556:Cystitis / Q000209:etiology; D004150:Dipeptidases; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000201:enzymology / Q000209:etiology*
D004150:Dipeptidases; C022449:proline dipeptidase