Peptic ulcer disease: new developments.
The wide array of medications aimed at all levels of acid secretion and at multiple levels of tissue function makes the choice of appropriate treatment for individual patients a challenge. The breakthrough development of cimetidine, followed by the rapid proliferation of new H2-receptor antagonists, new insights into parietal cell function, and the growth in our understanding of mucosal defense will make the treatment of peptic ulcer disease the challenge of the 1990s.
Nostrant
T T
TT
University of Michigan Medical Center, Department of Internal Medicine, Ann Arbor.
Barnett
J L
JL
D006801:Humans; D010437:Peptic Ulcer / Q000188:drug therapy* / Q000209:etiology; D012008:Recurrence