title: Experimental models in drug development for helminthic diseases.
abstract: The prevalence and socioeconomic impact of helminthic infections continue to be of global concern, particularly in areas with tropical climates, poor sanitation, low standards of living, and poor health education. Considerable progress has been achieved in the development of anthelmintics, and a number of useful model systems are available. The uses and pharmacologic and clinical features of a number of anthelmintics are reviewed.
authors.affiliation: Central Drug Research Institute, Lucknow, India.
authors.forename: J C
authors.initials: JC
authors.lastname: Katiyar
authors.forename: S
authors.initials: S
authors.lastname: Gupta
authors.forename: S
authors.initials: S
authors.lastname: Sharma
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D004195:Disease Models, Animal; D015195:Drug Design; D006373:Helminthiasis / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans
chemical_list: D000871:Anthelmintics