Vitamins A and E in RPE lipofuscin formation and implications for age-related macular degeneration.
Eldred
G E
GE
Department of Ophthalmology, University of Missouri, School of Medicine, Columbia 65212.
D000375:Aging / Q000378:metabolism*; D005453:Fluorescence; D006801:Humans; D015227:Lipid Peroxidation; D008062:Lipofuscin / Q000096:biosynthesis*; D008268:Macular Degeneration / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D010084:Oxidation-Reduction; D010786:Photoreceptor Cells; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D010860:Pigments, Biological / Q000096:biosynthesis*; D013472:Sunlight / Q000009:adverse effects; D014801:Vitamin A / Q000378:metabolism*; D014810:Vitamin E / Q000378:metabolism*
D008062:Lipofuscin; D010860:Pigments, Biological; D014801:Vitamin A; D014810:Vitamin E