Introduction to immunocytochemistry.
Immunocytochemistry has opened a new era in research and diagnosis. The development of immunocytochemical methods has made it possible to identify in situ normal and pathological tissue constituents, which it has not been possible to detect using ordinary histological methods. However, immunocytochemical techniques involve several pitfalls, which without proper control protocols can easily lead to incorrect findings. When interpreting the results obtained, account must always be taken of the morphological findings from routine histological sections. In other words, it is essential to understand the principles of these methods as well as to have enough basic knowledge in the field of research interest for making correct conclusions of the immunocytochemical findings.
Happonen
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RP
Heikinheimo
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D006801:Humans; D007150:Immunohistochemistry / Q000379:methods*