[Candida species produce IgA proteases--an important biological property].
IgA-specific microbial proteases possess the ability to reduce the protective effects of secretory IgA antibodies. The fact that fungi such as Candida produce both IgA1-and IgA2-specific proteases has not been acknowledged in articles and discussions concerning the chronic Candida syndrome. Therefore a short survey of these interesting proteases is presented, along with hypotheses concerning alterations IgA fragments may induce in immunoregulation and uptake of antigens from the gut.
Kett
K
K
D002175:Candida / Q000201:enzymology / Q000276:immunology*; D010447:Peptide Hydrolases / Q000096:biosynthesis*; D012697:Serine Endopeptidases
D010447:Peptide Hydrolases; D012697:Serine Endopeptidases; C021433:IgA-specific serine endopeptidase
Candida produserer IgA-proteaser-en viktig biologisk egenskap.