title: [The role of vitamin B6 in tumor growth].
abstract: It has been demonstrated that vitamin B6 accumulated in an organism may stimulate the tumour growth as it participates in the formation of polyamines, 5,10-methylene tetrahydrofolic acid and in thymidylate synthetase conformation stabilization. Activation of the tumour growth with the vitamin B6 deficiency is shown to be induced by accumulation of blastomogenic metabolites of tryptophane. The question of vitamin B6 use in oncology remains unsolved.
authors.forename: M B
authors.initials: MB
authors.lastname: Chuvykin
mesh_terms: D000818:Animals; D006801:Humans; D009369:Neoplasms / Q000378:metabolism* / Q000473:pathology / Q000517:prevention & control; D011073:Polyamines / Q000378:metabolism; D011736:Pyridoxine / Q000378:metabolism* / Q000627:therapeutic use; D013763:Tetrahydrofolates / Q000378:metabolism; D013940:Thymidylate Synthase / Q000378:metabolism
chemical_list: D011073:Polyamines; D013763:Tetrahydrofolates; C013123:5,10-methylenetetrahydrofolic acid; D013940:Thymidylate Synthase; D011736:Pyridoxine
vernacular_title: Rol' vitamina B6 v opukholevom roste.