Regional distribution of dopamine D1 and D2 receptors in the nucleus accumbens of the rat.
Dopamine (DA) D1 receptor density was found to be significantly lower in the rostral than in the medial and caudal areas of the nucleus accumbens. This roughly followed the distribution of DA terminals. The distribution of DA D2 receptors did not follow the DA terminal distribution. DA D2 receptor number was lower in the ventrorostral and higher in the dorsomedial area than in any other area of the nucleus accumbens.
Allin
R
R
Department of Chemical Pathology, University of Stellenbosch, Tygerberg Hospital, South Africa.
Russell
V
V
Lamm
M
M
Taljaard
J
J
D000818:Animals; D001552:Benzazepines / Q000378:metabolism*; D002794:Choline / Q000493:pharmacokinetics; D004298:Dopamine / Q000493:pharmacokinetics; D008297:Male; D009714:Nucleus Accumbens / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D011954:Receptors, Dopamine / Q000378:metabolism*; D012686:Septal Nuclei / Q000378:metabolism*; D013134:Spiperone / Q000378:metabolism*
D001552:Benzazepines; D011954:Receptors, Dopamine; D013134:Spiperone; D002794:Choline; D004298:Dopamine