[Use of carbamazepine in trigeminal neuralgia].
The treatment efficiency was compared to blood carbamazepine++ levels in patients with trigeminal neuralgia which were treated with the drug over a long period. The parameters displayed a good (r = 0.70) correlation that resulted in a tendency to increase treatment effect with carbamazepine++ plasma concentration increase. The treatment proved most efficient and side effect-free in a concentration range of 5 to 10 micrograms/ml. The data on blood carbamazepine++ concentrations may be helpful in designing a controlled course of treatment.
Puzin
M n
Mn
Martynova
L A
LA
Sharov
M N
MN
Zherdev
V P
VP
Starose'lskaia
I A
IA
D000328:Adult; D000368:Aged; D001711:Biotransformation; D002220:Carbamazepine / Q000008:administration & dosage* / Q000097:blood / Q000493:pharmacokinetics; D002986:Clinical Trials as Topic; D004305:Dose-Response Relationship, Drug; D005260:Female; D006207:Half-Life; D006801:Humans; D008297:Male; D008875:Middle Aged; D014277:Trigeminal Neuralgia / Q000188:drug therapy* / Q000378:metabolism
D002220:Carbamazepine
Primenenie karbamazepina pri nevralgii troĭnichnogo nerva.