Multicentric familial squamous odontogenic tumor.
Three cases of multicentric squamous odontogenic tumor, one of which was previously reported, are presented in three black siblings. A review of the literature indicates that 5 of the 26 previously recorded cases arose in multiple sites, but no evidence of familial history has been suggested. Although squamous odontogenic tumor has been described as a relatively rare, benign odontogenic neoplasm, the multicentric familial nature of our present cases suggests this represents either a reactive hyperplasia or hamartoma of residual odontogenic epithelium within the periodontal tissues. Management of previous cases has varied from simple curettage to maxillectomy with only one case of recurrence.
Leider
A S
AS
Department of Diagnostic Sciences, University of the Pacific School of Dentistry, San Francisco, Calif.
Jonker
L A
LA
Cook
H E
HE
D000328:Adult; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000235:genetics* / Q000473:pathology; D008441:Maxillary Neoplasms / Q000235:genetics* / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000235:genetics* / Q000473:pathology; D009808:Odontogenic Tumors / Q000235:genetics* / Q000473:pathology