title: Elimination of contaminating Escherichia coli peptides in the purification of Escherichia coli-derived recombinant human interferon-beta 1 by zinc chelate affinity chromatography.
authors.affiliation: Basic Research Laboratories, Toray Industries, Inc., Kanagawa, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Utsumi
authors.forename: I
authors.initials: I
authors.lastname: Yamamoto-Terasawa
authors.forename: S
authors.initials: S
authors.lastname: Yamazaki
authors.forename: H
authors.initials: H
authors.lastname: Shimizu
mesh_terms: D002846:Chromatography, Affinity; D004340:Drug Contamination; D004926:Escherichia coli / Q000378:metabolism*; D006801:Humans; D007370:Interferon Type I / Q000096:biosynthesis / Q000302:isolation & purification*; D010455:Peptides / Q000302:isolation & purification*; D011994:Recombinant Proteins
chemical_list: D007370:Interferon Type I; D010455:Peptides; D011994:Recombinant Proteins