title: Osteoinduction: a report on the discovery and research of unique protein growth factors mediating bone development.
abstract: Osteoinductive factor, a unique glycoprotein, is the latest growth factor to be discovered. When combined with transforming growth factor-beta 1 or transforming growth factor-beta 2, osteoinductive factor can stimulate the formation of endochondral bone in a collagen-ceramic composite. Preliminary laboratory studies indicate a wide potential for the use of osteoinductive products in orthopedics, oral reconstruction, and periodontal procedures.
authors.affiliation: Cellular Biochemistry Department, Collagen Corporation, Palo Alto, Calif.
authors.forename: S M
authors.initials: SM
authors.lastname: Seyedin
mesh_terms: D019485:Bone Morphogenetic Proteins; D006133:Growth Substances / Q000302:isolation & purification / Q000502:physiology*; D006801:Humans; D010012:Osteogenesis; D011506:Proteins / Q000302:isolation & purification / Q000502:physiology*; D015291:Transforming Growth Factors / Q000302:isolation & purification / Q000502:physiology
chemical_list: D019485:Bone Morphogenetic Proteins; D006133:Growth Substances; D011506:Proteins; D015291:Transforming Growth Factors