title: [Acute submassive cholestatic hepatitis after treatment with carbimazole. Presentation of a new case and review of the literature].
abstract: Carbimazole, an antithyroid agent of the thioimidazole group, can induce unpredictable liver alterations, presumably by hypersensitivity. We describe the case of a hyperthyroid woman who suffered acute submassive cholestatic hepatitis in the course of treatment with this drug. We also review the other seven cases of carbimazole hepatotoxicity previously communicated in the literature.
authors.forename: D
authors.initials: D
authors.lastname: Moreno Sánchez
authors.forename: J
authors.initials: J
authors.lastname: Medina Asensio
authors.forename: F
authors.initials: F
authors.lastname: Colina Ruiz-Delgado
authors.forename: R
authors.initials: R
authors.lastname: Campos Cantero
authors.forename: L
authors.initials: L
authors.lastname: Crespo Rincón
authors.forename: A
authors.initials: A
authors.lastname: Belda Serna
mesh_terms: D000208:Acute Disease; D000368:Aged; D002231:Carbimazole / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000150:complications / Q000209:etiology* / Q000473:pathology; D002779:Cholestasis / Q000139:chemically induced* / Q000150:complications / Q000473:pathology; D005260:Female; D006801:Humans
chemical_list: D002231:Carbimazole
vernacular_title: Hepatitis colestásica aguda submasiva tras tratamiento con carbimazol. Aportación de un caso y revisión de la literatura.