[A multiinstitutional prospective randomized study of radiation therapy of bone metastasis. II. Prognostic factors].
A prospective randomized study for the analysis of optimal schedule for the patients with bone metastases was performed. From February 1986 through January 1987, a total of 131 patients entered on this trial. The data from 129 patients out of 131 were available for the analysis of prognostic factors by Cox's regression model. As a whole, it was clear that first significant prognostic factor was urinary hydroxyproline/creatinine ratio (p = 0.0001), second primary site (p = 0.0001), third pain score (p = 0.0005) and fourth other organ metastasis except bone (p = 0.0006). In the group of lung cancer, first significant prognostic factor was urinary hydroxyproline/creatinine ratio (p = 0.0007), second multiplicity of bone metastasis (p = 0.0113), and third pain score (p = 0.0270).
Teshima
T
T
Chatani
M
M
Inoue
T
T
Hirokawa
Y
Y
Wadasaki
K
K
Kasiwado
K
K
Kagemoto
M
M
Katsuta
S
S
Honke
Y
Y
Koyama
T
T
D001859:Bone Neoplasms / Q000401:mortality / Q000532:radiotherapy* / Q000556:secondary; D003404:Creatinine / Q000652:urine; D006801:Humans; D006909:Hydroxyproline / Q000652:urine; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology; D015337:Multicenter Studies as Topic; D011379:Prognosis; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D013997:Time Factors
D003404:Creatinine; D006909:Hydroxyproline