The prophylactic activity of amoxycillin/clavulanate and cefoxitin in vascular surgery--a randomized clinical study.
In a randomized clinical study, 141 patients who had to undergo operations on the aorta or the main arteries received either amoxycillin/clavulanate or cefoxitin perioperatively for prophylaxis. As no wound infection occurred amoxycillin/clavulanate and cefoxitin were found to be equal in effectiveness.
Dieterich
H J
HJ
Institute of Anaesthesiology, Ludwig-Maximilians-University, Klinikum Grosshadern, Munich, FRG.
Groh
J
J
Behringer
K
K
Lauterjung
L
L
Martin
E
E
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000658:Amoxicillin / Q000627:therapeutic use*; D019980:Amoxicillin-Potassium Clavulanate Combination; D002440:Cefoxitin / Q000627:therapeutic use*; D002969:Clavulanic Acids / Q000627:therapeutic use*; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016032:Randomized Controlled Trials as Topic; D013530:Surgical Wound Infection / Q000382:microbiology / Q000517:prevention & control*; D014656:Vascular Surgical Procedures
D002969:Clavulanic Acids; D002440:Cefoxitin; D019980:Amoxicillin-Potassium Clavulanate Combination; D000658:Amoxicillin