Intraperitoneal chemotherapy in peritoneal malignancy: impact of intensive system care on practicability.
In a group of 31 patients a port-a-cath-system for intraperitoneal chemotherapy was installed. From 23 evaluable patients 9 showed a tumor remission, but only 1 was a patient with gastrointestinal carcinoma. All others were patients with ovarial carcinoma. The median survival rate of all patients was 9 months after implantation of the intraperitoneal catheter. 50% of all patients with gastrointestinal carcinoma died within the first 6 months, only 1 of 11 patients with ovarial carcinoma died in this period.
Knüsli
C
C
Department of Internal Medicine, University of Basel, Switzerland.
Ruff
P
P
Laffer
U
U
Stoll
H R
HR
Obrist
R
R
Weber
W
W
Obrecht
J P
JP
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016190:Carboplatin; D002408:Catheters, Indwelling; D002945:Cisplatin / Q000008:administration & dosage; D003422:Critical Care; D004341:Drug Evaluation; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage*; D005500:Follow-Up Studies; D005770:Gastrointestinal Neoplasms / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D010534:Peritoneal Neoplasms / Q000188:drug therapy / Q000556:secondary*; D012189:Retrospective Studies
D009944:Organoplatinum Compounds; D016190:Carboplatin; D002945:Cisplatin; D005472:Fluorouracil