title: [Extra-gonadal germ-cell tumors].
abstract: Authors describe the clinico-pathological and immunohistochemical findings of two mediastinal (seminoma and yolk-sack) and a pineal mixed (seminoma and yolk-sack) tumours. In the mediastinal yolk-sack tumour the light microscopic picture of cellular components, alpha-fetoprotein (AFP), haemoglobin F (Hgb F), blood group antigen, carcinoembryonal antigen (CEA), post-digestion (neuraminidase) peanut antigen (neu-PNA) positivities suggest hepatic and intestinal differentiation. In some cells of mediastinal seminoma the glucose- and mannose-binding concanavalin-A (Con A) showed reaction. In the mixed tumour of the pineal region in addition to AFP positive cell cords some cell groups reacted with Leu-M1 (CD15) monoclonal antibodies raised against stage specific embryonic antigen 1 (SSEA1).
authors.forename: F
authors.initials: F
authors.lastname: Baranyay
authors.forename: F
authors.initials: F
authors.lastname: Brittig
authors.forename: T
authors.initials: T
authors.lastname: Magyarlaki
authors.forename: A
authors.initials: A
authors.lastname: Páalvölgyi
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000473:pathology*; D004407:Dysgerminoma / Q000473:pathology*; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000473:pathology*; D010870:Pineal Gland / Q000473:pathology*
vernacular_title: Az extragonadalis csírasejtes tumorokról.