PET and movement disorders.
In this paper the use of PET for determining the patterns of disruption of both regional cerebral metabolism, and the pre- and post-synaptic dopaminergic systems, associated with movement disorders is reviewed. That the various akinetic-rigid syndromes result in distinctive PET findings is shown, making functional imaging valuable in their differential diagnosis. PET may also be useful for detecting the presence of sub-clinical disease in Huntington's disease and other inherited movement disorders.
Brooks
D J
DJ
MRC Cyclotron Unit, Hammersmith Hospital, London, UK.
Frackowiak
R S
RS
D001786:Blood Glucose / Q000378:metabolism; D001921:Brain / Q000000981:diagnostic imaging; D002560:Cerebrovascular Circulation; D004734:Energy Metabolism; D006801:Humans; D009069:Movement Disorders / Q000000981:diagnostic imaging*; D010300:Parkinson Disease / Q000000981:diagnostic imaging*; D011954:Receptors, Dopamine / Q000378:metabolism; D014055:Tomography, Emission-Computed
D001786:Blood Glucose; D011954:Receptors, Dopamine