The impact of thiols for insulin secretion.
The review summarizes the present state to be known on regulation of insulin secretion. Special attention is drawn on the impact of ion fluxes and the redox state of pancreatic beta-cells stimulated with different secretagogues.
Ammon
H P
HP
Department of Pharmacology, Eberhard-Karls-University, Tübingen, FRG.
Wahl
M A
MA
D000818:Animals; D002118:Calcium / Q000378:metabolism / Q000493:pharmacokinetics; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000166:cytology / Q000378:metabolism; D010084:Oxidation-Reduction; D011188:Potassium / Q000378:metabolism / Q000493:pharmacokinetics; D051381:Rats; D013438:Sulfhydryl Compounds / Q000494:pharmacology*
D007328:Insulin; D013438:Sulfhydryl Compounds; D011188:Potassium; D002118:Calcium