title: Update on the epidemiology of multiple sclerosis.
abstract: Neuroepidemiology has been important in providing clues about the cause and pathogenesis of multiple sclerosis. In this review, we update the incidence and prevalence rates of multiple sclerosis in Olmsted County, Minnesota, and examine the potential role of viruses, exposure to animals, toxins, trauma, and diet in the development of this disease. Diseases of probable autoimmune nature have also been linked to multiple sclerosis. These descriptive data may contribute to the formulation of testable specific hypotheses about the pathogenesis and treatment of multiple sclerosis and other demyelinating diseases.
authors.forename: D R
authors.initials: DR
authors.lastname: Wynn
authors.forename: M
authors.initials: M
authors.lastname: Rodriguez
authors.forename: W M
authors.initials: WM
authors.lastname: O'Fallon
authors.forename: L T
authors.initials: LT
authors.lastname: Kurland
mesh_terms: D000367:Age Factors; D003141:Communicable Diseases / Q000150:complications; D005260:Female; D014943:Global Health; D006801:Humans; D008297:Male; D008670:Metals / Q000009:adverse effects; D008910:Minnesota; D009103:Multiple Sclerosis / Q000453:epidemiology* / Q000209:etiology; D012737:Sex Factors; D014171:Transients and Migrants; D014947:Wounds and Injuries / Q000150:complications
chemical_list: D008670:Metals