title: The B subunit of coagulation factor XIII is linked to renin and the Duffy blood group to alpha-spectrin on human chromosome 1.
abstract: Family linkage studies were used to detect two linkage relationships on human chromosome 1. The B subunit of coagulation factor XIII showed significant linkage to renin with a maximum lod score of 5.071 at a distance of 10 cM. Significant linkage was also shown between the Duffy blood group and alpha-spectrin with linkage results giving a combined lod score of 3.194 at 5 cM.
authors.affiliation: Department of Medicine, University of Sydney, Australia.
authors.forename: L R
authors.initials: LR
authors.lastname: Griffiths
authors.forename: P G
authors.initials: PG
authors.lastname: Board
authors.forename: M B
authors.initials: MB
authors.lastname: Zwi
authors.forename: B J
authors.initials: BJ
authors.lastname: Morris
authors.forename: J G
authors.initials: JG
authors.lastname: McLeod
authors.forename: G A
authors.initials: GA
authors.lastname: Nicholson
mesh_terms: D001789:Blood Group Antigens / Q000235:genetics*; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D004375:Duffy Blood-Group System / Q000235:genetics*; D005176:Factor XIII / Q000235:genetics*; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D011995:Recombination, Genetic; D012083:Renin / Q000235:genetics*; D013049:Spectrin / Q000235:genetics*
chemical_list: D001789:Blood Group Antigens; D004375:Duffy Blood-Group System; D005819:Genetic Markers; D013049:Spectrin; D005176:Factor XIII; D012083:Renin