[Nonsteroid anti-inflammatory drugs in elderly patients].
Incidence of side effects of nonsteroid anti-inflammatory drugs is greater in elderly patients. The author describes the reason why these drugs cause frequent and serious side effects. Particularly important is the difference between elderly and young patients in terms of metabolism and excretion of nonsteroid anti-inflammatory drugs. In general, nonsteroid anti-inflammatory drugs with a long half-life should not be given to elderly patients. The author also describes guidelines for nonsteroid anti-inflammatory drugs treatment in elderly patients.
Mizushima
Y
Y
D000368:Aged; D000375:Aging / Q000378:metabolism; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D006801:Humans
D000894:Anti-Inflammatory Agents, Non-Steroidal