Determination of monoclonality from sequential dilution assays.
The statistical framework necessary to assess clonality following a multi-stage cloning procedure is described. A computer program implementing the requisite calculations is available.
Koziol
J A
JA
Department of Basic and Clinical Research, Research Institute of Scripps Clinic, La Jolla, CA 92037.
D000465:Algorithms; D002452:Cell Count / Q000379:methods; D002460:Cell Line; D003001:Cloning, Molecular / Q000379:methods*; D006511:Hepatitis B Antigens / Q000032:analysis; D007201:Indicator Dilution Techniques; D011336:Probability; D011381:Programming Languages; D011897:Random Allocation; D013601:T-Lymphocytes / Q000276:immunology
D006511:Hepatitis B Antigens