Serum enzymes in disease of skeletal muscle.
Creatine kinase is the serum enzyme that shows the greatest frequency of abnormality in skeletal muscle disease. Changes in this enzyme in sex-linked dystrophy (Duchenne's and Becker's) patients and carriers; in patients with other dystrophies; and in inflammatory, toxic, endocrine, and traumatic myopathy are reviewed. The changing role of serum enzyme measurements as a consequence of newer methods of genetic diagnosis is also considered.
Rosalki
S B
SB
Department of Chemical Pathology and Human Metabolism, Royal Free Hospital and School of Medicine, London, United Kingdom.
D003402:Creatine Kinase / Q000097:blood; D004274:DNA, Recombinant; D006580:Genetic Carrier Screening; D006801:Humans; D009135:Muscular Diseases / Q000201:enzymology*; D009136:Muscular Dystrophies / Q000175:diagnosis / Q000201:enzymology / Q000235:genetics; D009220:Myositis / Q000201:enzymology
D004274:DNA, Recombinant; D003402:Creatine Kinase