title: [Malaria in Guiana. I. General status of the endemic].
abstract: Before 1949 malaria was highly prevalent in the whole territory of French Guiana. When malaria control based on house-spraying and drug prophylaxis was implemented in 1950 the disease sharply dropped below 20 cases per year. Since 1976 despite vector control malaria is rising again. In 1987, 3,269 cases have been notified giving an incidence of 37.6 per thousand for the whole country population; only four deaths were recorded. All the age groups were concerned but the transmission was restricted to some foci along the Oyapock river (prevalence rate 25%), along the Maroni river (prevalence 2.3%) and in a few places of the coastal area. The main cities remain malaria free. In vivo resistance to chloroquine was observed in 22% of the cases which could be cleared by amodiaquine or quinine.
authors.affiliation: Conseil Général de Guyane, Cayenne.
authors.forename: L
authors.initials: L
authors.lastname: Lepelletier
authors.forename: F
authors.initials: F
authors.lastname: Gay
authors.forename: M
authors.initials: M
authors.lastname: Nadire-Galliot
authors.forename: J P
authors.initials: JP
authors.lastname: Poman
authors.forename: S
authors.initials: S
authors.lastname: Bellony
authors.forename: J
authors.initials: J
authors.lastname: Claustre
authors.forename: B M
authors.initials: BM
authors.lastname: Traore
authors.forename: J
authors.initials: J
authors.lastname: Mouchet
mesh_terms: D000293:Adolescent; D000328:Adult; D000655:Amodiaquine / Q000627:therapeutic use; D000818:Animals; D002648:Child; D002675:Child, Preschool; D002738:Chloroquine / Q000627:therapeutic use; D004351:Drug Resistance; D005616:French Guiana; D049670:History, 17th Century; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D007223:Infant; D008288:Malaria / Q000453:epidemiology* / Q000266:history; D010963:Plasmodium falciparum / Q000187:drug effects; D010966:Plasmodium vivax / Q000187:drug effects; D011803:Quinine / Q000627:therapeutic use
chemical_list: D000655:Amodiaquine; D002738:Chloroquine; D011803:Quinine
vernacular_title: Le paludisme en Guyane. I. Situation générale de l'endémie.