title: Presbyopia toward the end of the 20th century.
abstract: Recent advances in our understanding of the anatomy and physiology of accommodation have contributed to current concepts of the possible constituent factors in presbyopia, largely supplanting the long-held belief that presbyopia is due to sclerosis of the crystalline lens. In this review, the author examines epidemiologic, basic scientific, and clinical evidence for a multifactorial decrease in accommodative amplitude with age. Methods of measurement, oculomotor effects of presbyopia, and approaches to correcting it are also considered.
authors.affiliation: Department of Clinical Ophthalmology, Institute of Ophthalmology, University of London, Moorfields Eye Hospital, England.
authors.forename: R
authors.initials: R
authors.lastname: Weale
mesh_terms: D000065:Accommodation, Ocular; D000328:Adult; D000375:Aging / Q000502:physiology; D006801:Humans; D007908:Lens, Crystalline / Q000254:growth & development; D009801:Oculomotor Muscles / Q000502:physiology; D011305:Presbyopia / Q000209:etiology* / Q000235:genetics