Antimicrobial activity of some 2-aminopyrimidines.
The minimum inhibitory concentration values for a group of pyrimidine derivatives were determined for Gram-positive and Gram-negative bacteria and yeast. The active compounds were further screened. The effect of these compounds on growth and morphology was tested, and their structural antimicrobial activity is discussed.
Ghannoum
M
M
Department of Botany and Microbiology, University of Kuwait, Safat.
Abu Elteen
K
K
el-Rayyes
N R
NR
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development / Q000648:ultrastructure; D002176:Candida albicans / Q000187:drug effects / Q000254:growth & development; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D011743:Pyrimidines / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development / Q000648:ultrastructure; D013329:Structure-Activity Relationship; D015003:Yeasts / Q000187:drug effects* / Q000254:growth & development / Q000648:ultrastructure
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D011743:Pyrimidines