title: Multiple genes are transcribed in Hordeum vulgare and Zea mays that carry the DNA binding domain of the myb oncoproteins.
abstract: cDNA clones were isolated from tissue specific cDNA libraries of barley and maize using as a probe the cDNA of the maize gene C1, a regulator of anthocyanin gene expression. C1-related homology for all of the four cDNAs characterized by sequence analysis is restricted to the N-terminal 120 amino acids of the putative proteins. This region shows striking homology to the N-proximal domain of the myb oncoproteins from vertebrates and invertebrates. Within the myb proto-oncogene family this part of the respective gene products functions as a DNA binding domain. Acidic domains are present in the C-proximal protein segments. Conservation of these sequences, together with the genetically defined regulator function of the C1 gene product, suggest that myb-related plant genes code for trans-acting factors which regulate gene expression in a given biosynthetic pathway.
authors.affiliation: Max-Planck-Institut für Züchtungsforschung, Köln, Federal Republic of Germany.
authors.forename: A
authors.initials: A
authors.lastname: Marocco
authors.forename: M
authors.initials: M
authors.lastname: Wissenbach
authors.forename: D
authors.initials: D
authors.lastname: Becker
authors.forename: J
authors.initials: J
authors.lastname: Paz-Ares
authors.forename: H
authors.initials: H
authors.lastname: Saedler
authors.forename: F
authors.initials: F
authors.lastname: Salamini
authors.forename: W
authors.initials: W
authors.lastname: Rohde
mesh_terms: D000595:Amino Acid Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics; D001467:Hordeum / Q000235:genetics; D008969:Molecular Sequence Data; D010940:Plant Proteins / Q000235:genetics*; D010944:Plants / Q000235:genetics*; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D020598:Proto-Oncogene Proteins c-myb; D003313:Zea mays / Q000235:genetics
chemical_list: D004268:DNA-Binding Proteins; D010940:Plant Proteins; D011518:Proto-Oncogene Proteins; D020598:Proto-Oncogene Proteins c-myb; D004247:DNA