title: Isolation of human fungi from soil and identification of two endemic areas of Cryptococcus neoformans and Coccidioides immitis.
abstract: The present study was carried out in two different areas of Province of Cordoba, Argentina, where there was a suspicious of endemic mycosis. The previous data were the presence of a clinical case of pulmonary cryptococcosis in one area (Alta Gracia) and the previous findings of a high incidence of coccidioidin and cryptococcin reactors in the population of the second one (Villa Dolores). In both areas soil samples for fungi were studied and Cryptococcus neoformans was found in 2/25 samples from Alta Gracia. In Villa Dolores Coccidioides immitis was isolated in 2/40 samples, and C. neoformans in 1/40 samples. Delayed hypersensitivity test with cryptococcin was determined in the population from Alta Gracia and it was found to be 5.3%. Positive cutaneous tests with coccidioidin (33.8%) and cryptococcin (31.9%) in Villa Dolores were obtained. With these findings two endemic areas of systemic mycoses in Cordoba, Argentina were delimited.
authors.forename: H
authors.initials: H
authors.lastname: Rubinstein
authors.forename: B
authors.initials: B
authors.lastname: Marticorena
authors.forename: D
authors.initials: D
authors.lastname: Masih
authors.forename: N
authors.initials: N
authors.lastname: Borletto
authors.forename: R
authors.initials: R
authors.lastname: Vega
authors.forename: H
authors.initials: H
authors.lastname: Varengo
authors.forename: R
authors.initials: R
authors.lastname: Negroni
mesh_terms: D000293:Adolescent; D000328:Adult; D001118:Argentina; D003045:Coccidioides / Q000302:isolation & purification*; D003047:Coccidioidomycosis / Q000453:epidemiology*; D003453:Cryptococcosis / Q000453:epidemiology*; D003454:Cryptococcus / Q000302:isolation & purification*; D003455:Cryptococcus neoformans / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012882:Skin Tests; D012988:Soil Microbiology