title: Spontaneous streptococcal gangrenous myositis: survival with early debridement.
abstract: Spontaneous gangrenous myositis caused by Streptococcus pyogenes is usually fatal, but no longer uniformly so. There appears to be a spectrum of disease due to beta-hemolytic streptococci, from necrotizing fasciitis to pyomyositis to spontaneous gangrenous myositis. Survival is possible with early surgical debridement, reexploration at 24 to 36 hours, and intensive supportive care.
authors.affiliation: Department of Internal Medicine, College of Medicine, University of Iowa Hospitals and Clinics, Iowa City 52242.
authors.forename: B N
authors.initials: BN
authors.lastname: Doebbeling
authors.forename: R P
authors.initials: RP
authors.lastname: Wenzel
mesh_terms: D000368:Aged; D003131:Combined Modality Therapy; D003646:Debridement; D005734:Gangrene / Q000628:therapy; D006801:Humans; D008297:Male; D009220:Myositis / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D010400:Penicillin G / Q000627:therapeutic use; D013290:Streptococcal Infections / Q000473:pathology / Q000628:therapy*; D013297:Streptococcus pyogenes / Q000302:isolation & purification
chemical_list: D010400:Penicillin G