Reactivity between monoclonal anti-HLA-B27 antibodies and bacterial components: is there a consensus of findings?
Studies addressing the molecular aspects of the postulated cross-reactivity between the HLA-B27 antigens and the bacteria known to precipitate arthritis (e.g., Shigella, Salmonella, Yersinia and Campylobacter) are reviewed. In conclusion, the necessity for further research into the pathogenesis of arthritis is stressed.
Ren
M N
MN
Department of Medicine, University of California Center for Health Sciences, Los Angeles 90024.
Zhang
J J
JJ
Nakayama
A
A
Yu
D T
DT
D000595:Amino Acid Sequence; D000911:Antibodies, Monoclonal / Q000276:immunology*; D001170:Arthritis, Infectious / Q000276:immunology; D001425:Bacterial Outer Membrane Proteins / Q000276:immunology*; D003429:Cross Reactions / Q000276:immunology*; D004755:Enterobacteriaceae / Q000276:immunology; D015796:HLA-B27 Antigen / Q000276:immunology*; D006801:Humans; D008969:Molecular Sequence Data
D000911:Antibodies, Monoclonal; D001425:Bacterial Outer Membrane Proteins; D015796:HLA-B27 Antigen