Pain on injection and venous sequelae following two formulations of etomidate.
In forty patients (aged 21-76 years) scheduled for elective surgery, anaesthesia was induced with either etomidate in propylene glycol (n = 20) or etomidate in ethanol (n = 20) injected via a 23-G needle over 30 s. The overall incidence of pain on injection was 60%. No statistically significant difference was found between the two groups. The incidence of venous sequelae was 5%, in both groups.
Ganta
R
R
Derbyshire Royal Infirmary, United Kingdom.
Verma
R
R
D000328:Adult; D000368:Aged; D000771:Anesthesia, Intravenous / Q000009:adverse effects*; D000431:Ethanol / Q000008:administration & dosage; D005045:Etomidate / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000209:etiology*; D019946:Propylene Glycol; D011409:Propylene Glycols / Q000008:administration & dosage; D016032:Randomized Controlled Trials as Topic; D013924:Thrombophlebitis / Q000139:chemically induced*
D011409:Propylene Glycols; D000431:Ethanol; D019946:Propylene Glycol; D005045:Etomidate