Immunopathology of polymorphic reticulosis of the larynx.
We treated a 28-year-old woman with initial symptoms of hoarseness. At biopsy, atypical lymphoid cells infiltrate was observed in the submucosa of the larynx and polymorphic reticulosis was diagnosed. Immunohistochemical examination of the laryngeal material obtained at autopsy revealed a strong reaction of lymphoid cells to the monoclonal antibody to human T lymphocytes. The possibility that polymorphic reticulosis is a transitional form of peripheral T cell lymphoma was confirmed.
Nakashima
T
T
Department of Otolaryngology, National Kyushu Cancer Center, Fukuoka, Japan.
Inamitsu
M
M
Uemura
T
T
Sugimoto
T
T
D000328:Adult; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007822:Laryngeal Neoplasms / Q000276:immunology / Q000473:pathology*; D007830:Larynx / Q000473:pathology; D008206:Lymphatic Diseases / Q000276:immunology / Q000473:pathology*; D008223:Lymphoma / Q000276:immunology / Q000473:pathology*; D013601:T-Lymphocytes / Q000276:immunology*