title: [Evaluation of the insulin requirements with an artificial pancreas in gestational diabetes].
abstract: The evolution of insulin requirements in 10 patients with gestational diabetes mellitus was evaluated with the use of an artificial pancreas. We found that intravenous insulin requirements showed a definite tendency to decline, the greatest reduction being found between gestational weeks 27 and 37. Postprandial requirements after lunch were significantly higher in the weeks 15 and 27, with a tendency to become equal to those corresponding to breakfast and dinner in week 37. We found a lack of lineal correlation between the intravenous and subcutaneous requirements. We conclude that the artificial pancreas is a useful instrument to examine in detail the temporal evolution of insulin requirements in gestational diabetes. The artificial pancreas facilitates the adjustment of insulin therapy and plays a major role in the understanding of the pathophysiological abnormalities in these patients.
authors.forename: I
authors.initials: I
authors.lastname: Fernández
authors.forename: M A
authors.initials: MA
authors.lastname: Rodríguez
authors.forename: A
authors.initials: A
authors.lastname: Gutiérrez
authors.forename: C J
authors.initials: CJ
authors.lastname: Costa
authors.forename: J
authors.initials: J
authors.lastname: Sánchez Ramos
authors.forename: S
authors.initials: S
authors.lastname: Durán García
mesh_terms: D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D007279:Injections, Subcutaneous; D007328:Insulin / Q000008:administration & dosage / Q000627:therapeutic use*; D007332:Insulin Infusion Systems; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000188:drug therapy*
chemical_list: D007328:Insulin
vernacular_title: Valoración de los requerimientos insulínicos con páncreas artificial en la diabetes gestacional.