Aneuploidy as a prognostic factor in breast cancer.
The predictive value of nuclear DNA content in mammary carcinoma is still under debate in spite of several reports indicating a relationship between DNA ploidy and prognosis. The impact of differences in methodology on the evaluation of DNA data is discussed, and a recent study demonstrating DNA ploidy as a statistically significant prognostic variable on a prospective material of breast cancer patients is presented.
von Rosen
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Department of Surgery, Södersjukhuset, Stockholm, Sweden.
D000782:Aneuploidy; D001943:Breast Neoplasms / Q000235:genetics*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D011379:Prognosis