[Evaluation of the immunologic response in various types of bone grafts using lymphocytic nucleoli activity].
Assessment of the activity of nucleoli in lymphocytes is considered an important sign for assessment of the degree of activation of the immune system after transplantation. The authors evaluated the activity of nucleoli in lymphocytes of patients with transplantations of different types of bony tissues (autografts, frozen alloimplants, autolyzed antigen-free allogenic bone, control group) before operation, two weeks, 70 days and longer after operation. Differences were revealed during the period between two weeks and 70 days after operation. While in autografts and autolyzed antigen-free allogenic bone at that time a slight decline of inactivated forms of lymphocytes occurred, in frozen alloimplants a rise was recorded. The number of active forms of lymphocytes increased in autolyzed antigen-free allogenic bone and declined in frozen alloimplants. In autografts a mild decline was recorded in active as well as inactive forms of lymphocytes at the expense of an increased number of annular nucleoli. In the conclusion the authors present different interpretations.
Janovec
M
M
Petrzelová
J
J
Navrátil
P
P
D000293:Adolescent; D016025:Bone Transplantation; D002466:Cell Nucleolus / Q000276:immunology / Q000473:pathology*; D002648:Child; D006801:Humans; D008214:Lymphocytes / Q000276:immunology / Q000648:ultrastructure*; D009926:Organ Preservation; D014181:Transplantation Immunology; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous
Hodnocení imunologické odpovĕdi různých typů kostních transplantátů pomocí aktivity jadérek lymfocytů.