title: Brain abscess due to Nocardia.
abstract: Cerebral Nocardiosis is a rare disease, usually occurring in immunocompromised hosts. We report here two cases of brain abscess due to Nocardia species-one due to usual N. asteroides and other by uncommon N. caviae. N. asteroides affected the brain in a post renal transplant patient, whereas N. caviae caused infection of brain in an apparently healthy individual. To the best of our knowledge, all the previous cases of brain abscess due to Nocardia caviae have been reported in compromised hosts. Agar dilution antimicrobial testing showed relatively higher resistant pattern in N. asteroides. In spite of antimicrobial therapy, both the patients succumbed, one within 4 days and other after an initial improvement for four weeks due to drainage of abscess.
authors.affiliation: Department of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
authors.forename: P
authors.initials: P
authors.lastname: Talwar
authors.forename: A
authors.initials: A
authors.lastname: Chakrabarti
authors.forename: A
authors.initials: A
authors.lastname: Ayyagari
authors.forename: N
authors.initials: N
authors.lastname: Nayak
authors.forename: V K
authors.initials: VK
authors.lastname: Khosla
authors.forename: M
authors.initials: M
authors.lastname: Minz
authors.forename: R V
authors.initials: RV
authors.lastname: Yadav
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001922:Brain Abscess / Q000209:etiology* / Q000382:microbiology; D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009617:Nocardia Infections / Q000209:etiology*; D009616:Nocardia asteroides / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents