title: Comparative enzymatic study of HPLC-fractionated Crotalus venoms.
abstract: 1. Ten venoms of the genus Crotalus (Crotalus adamanteus, Crotalus atrox, Crotalus durissus durissus, Crotalus horridus horridus, Crotalus lepidus, Crotalus polystictus, Crotalus molossus molossus, Crotalus pusillus, Crotalus scutulatus scutulatus, venom B, and Crotalus viridis lutosus) were fractionated using HPLC anion and cation exchange chromatography. 2. HPLC venom fractions were tested for hemorrhagic, hemolytic, and proteolytic activities. 3. Crude Virginia opossum (Didelphis virginiana) serum neutralized the hemorrhagic activity of HPLC fractions.
authors.affiliation: Department of Biology, Texas A&I University, Kingsville 78363.
authors.forename: J G
authors.initials: JG
authors.lastname: Soto
authors.forename: J C
authors.initials: JC
authors.lastname: Perez
authors.forename: M M
authors.initials: MM
authors.lastname: Lopez
authors.forename: M
authors.initials: M
authors.lastname: Martinez
authors.forename: T B
authors.initials: TB
authors.lastname: Quintanilla-Hernandez
authors.forename: M S
authors.initials: MS
authors.lastname: Santa-Hernandez
authors.forename: K
authors.initials: K
authors.lastname: Turner
authors.forename: J L
authors.initials: JL
authors.lastname: Glenn
authors.forename: R C
authors.initials: RC
authors.lastname: Straight
authors.forename: S A
authors.initials: SA
authors.lastname: Minton
mesh_terms: D000818:Animals; D000997:Antivenins / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D003435:Crotalid Venoms / Q000032:analysis* / Q000378:metabolism; D006461:Hemolysis; D006470:Hemorrhage / Q000139:chemically induced; D009893:Opossums; D010447:Peptide Hydrolases / Q000378:metabolism
chemical_list: D000997:Antivenins; D003435:Crotalid Venoms; D010447:Peptide Hydrolases