[Detection of HTLV-I viral antibodies in donor blood samples].
Sera from 867 donors were tested for antibodies to the virus of T-lymphocyte leukemia of adults (HTLV-I) in parallel by indirect immunofluorescence on acetone-fixed cells of HUT-102 culture producing HTLV-I and by agglutination test using a commercial set ("Serodia-ATLA", Japan). Twelve (1.38%) out of 867 sera were positive in the agglutination test and only 7 of them in immunofluorescence test. The specificity of the results was verified by absorption experiments. The activity of the sera in the agglutination test disappeared completely after their absorption with HUT-102 culture cells but did not change after absorption with LLU cells producing no HTLV-I despite a low percent of virus infection, donor blood control for HTLV-I infection becomes mandatory.
Iakovleva
L S
LS
Seniuta
N B
NB
Stepina
V N
VN
Gurtsevich
V E
VE
Buachidze
L N
LN
D000328:Adult; D000372:Agglutination Tests; D000918:Antibody Specificity; D001782:Blood Donors; D005260:Female; D005455:Fluorescent Antibody Technique; D015481:HTLV-I Antibodies / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009031:Moscow; D014505:Urban Population
D015481:HTLV-I Antibodies
Obnaruzhenie antitel k virusu HTLV-I v obraztsakh donorskoĭ krovi.