Hematological indices and the prevalence of anemia in an elderly Chinese population.
Hematological indices were determined in a group of 427 elderly Chinese subjects over 60 years old; reference ranges were established after excluding subjects with hemoglobinopathies or diseases giving rise to anemia and those with values less or greater than 3 SD from the mean. The values were similar to those for elderly Caucasians. All the red cell indices were significantly higher in men than women, possibly reflecting the influence of androgens on bone marrow function. Previously reported age-related decline in hemoglobin, red cell count and hematocrit from studies of all age groups was not seen in men or women above age 60 years, but a fall in platelet count with age, which had not been previously reported, was observed. There were no age-related changes in any other indices. Reference ranges were lower for Hb, MCV, and MCH in men and women, compared to those derived from a study of Chinese of all age groups. The prevalence of anemia due to disease and hemoglobinpathies in this population was 6.4% in men and 6.3% in women.
Woo
J
J
Department of Medicine, Prince of Wales Hospital, Chinese University of Hong Kong.
Arumanayagam
M
M
Ho
S C
SC
Swaminathan
R
R
D000368:Aged; D000375:Aging / Q000097:blood; D000740:Anemia / Q000097:blood / Q000453:epidemiology*; D002681:China; D004909:Erythrocyte Indices; D005260:Female; D006579:Heterozygote; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D012016:Reference Values