title: Fine-tuning of MHC class II gene expression in defined microenvironments.
abstract: Strict control of major histocompatibility complex class II gene expression is essential for proper functioning of the immune system. Recent transgenic mouse studies have revealed an intricate fine-tuning of class II gene transcription in microenvironments such as the germinal centers and thymic cortex and medulla.
authors.forename: H J
authors.initials: HJ
authors.lastname: Fehling
authors.forename: S
authors.initials: S
authors.lastname: Viville
authors.forename: W
authors.initials: W
authors.lastname: van Ewijk
authors.forename: C
authors.initials: C
authors.lastname: Benoist
authors.forename: D
authors.initials: D
authors.lastname: Mathis
mesh_terms: D000818:Animals; D001921:Brain / Q000276:immunology; D005786:Gene Expression Regulation; D000949:Histocompatibility Antigens Class II / Q000235:genetics*; D008214:Lymphocytes / Q000276:immunology; D008285:Major Histocompatibility Complex; D051379:Mice; D008822:Mice, Transgenic
chemical_list: D000949:Histocompatibility Antigens Class II