title: [Clinical results of using Nakom in diseases of the nervous system].
abstract: Clinical investigation was performed and dopamine metabolism (renal catecholamine excretion) studied in 29 children and 5 adults with various forms of CP, 5 myasthenic children and 1 child with Strümpel disease treated with Nakom. The therapy was judged expedient in 20% of the cases of pronounced muscular rigidity and dystonia with decreased dopamine excretion. The drug proved ineffective in atonic, astatic, severe hyperkinetic arms, and in cases with severe psycho-organic signs.
authors.forename: S K
authors.initials: SK
authors.lastname: Evtushenko
authors.forename: I A
authors.initials: IA
authors.lastname: Sadekov
authors.forename: R A
authors.initials: RA
authors.lastname: Samsonenko
authors.forename: G S
authors.initials: GS
authors.lastname: Mogilevskaia
authors.forename: L M
authors.initials: LM
authors.lastname: Prokhorova
authors.forename: S S
authors.initials: SS
authors.lastname: Ostropolets
authors.forename: V G
authors.initials: VG
authors.lastname: Osadchiĭ
authors.forename: M E
authors.initials: ME
authors.lastname: Va'skovskaia
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002230:Carbidopa / Q000627:therapeutic use*; D002395:Catecholamines / Q000652:urine; D002547:Cerebral Palsy / Q000188:drug therapy* / Q000652:urine; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004338:Drug Combinations / Q000627:therapeutic use; D004422:Dystonia Musculorum Deformans / Q000188:drug therapy* / Q000652:urine; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D009127:Muscle Rigidity / Q000188:drug therapy / Q000652:urine; D009157:Myasthenia Gravis / Q000188:drug therapy* / Q000652:urine
chemical_list: D002395:Catecholamines; D004338:Drug Combinations; C009265:carbidopa, levodopa drug combination; D007980:Levodopa; D002230:Carbidopa
vernacular_title: Klinicheskie rezu'ltaty primeneniia Nakoma pri zabolevaniiakh nervnoĭ sistemy.