[Prostaglandins--local regulators in bone?].
Since the initial discovery by Bergström, prostaglandin E has been the focus of an intense research effort in vitro and in vivo. The regulation of bone resorption and formation involves local as well as systemic factors. In the last decade, prostaglandins have been found to be intimately associated with bone metabolism. One hypothesis consistent that osteoblastic c AMP levels play a central role in determining whether osteoblasts stimulate or inhibit osteoclastic bone resorption. The osteoinductive properties of prostaglandins were discussed.
Bartels
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Hein
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Taube
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Mest
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HJ
D000818:Animals; D001861:Bone Regeneration; D001862:Bone Resorption / Q000503:physiopathology*; D006801:Humans; D010006:Osteoblasts / Q000502:physiology; D010010:Osteoclasts / Q000502:physiology; D011453:Prostaglandins / Q000502:physiology*
D011453:Prostaglandins
Prostaglandine--lokale Mediatoren im Knochen?