title: [Silastic implant and synovitis].
abstract: The silastic implant based on siloxane polymere induces granulomatous synovitis in certain predisposed individuals, a reaction which may continue even after removal of the implant. This is also true of a prosthesis of the trapezium in two of our patients, though to a lesser degree. This is probably the reason why the problem has not yet been widely recognized. The hypothesis is put forward that an enzymatic predisposition may allow chemical degradation of the fragmented silastic implant into a toxic component responsible for the pathologic condition. The slow progression of the lesions is a challenge for the future and puts in question the further use of silastic implants.
authors.affiliation: Chirurgie St-Léonard, Klinik für Hand- und ambulante Chirurgie, St. Gallen.
authors.forename: G
authors.initials: G
authors.lastname: Sennwald
mesh_terms: D000368:Aged; D002348:Carpal Bones / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D005549:Foreign-Body Reaction / Q000000981:diagnostic imaging*; D015745:Granuloma, Foreign-Body / Q000000981:diagnostic imaging*; D006801:Humans; D008875:Middle Aged; D010003:Osteoarthritis / Q000601:surgery*; D011183:Postoperative Complications / Q000000981:diagnostic imaging*; D019736:Prostheses and Implants; D011859:Radiography; D012826:Silicone Elastomers / Q000009:adverse effects*; D013585:Synovitis / Q000000981:diagnostic imaging*
chemical_list: D012826:Silicone Elastomers
vernacular_title: Silastic et synovialite.