title: Cavitation and other atypical manifestations of Pneumocystis carinii pneumonia.
abstract: In the 1980s, under the impact of the acquired immune deficiency syndrome, Pneumocystis carinii Pneumonia (PCP) has become the prime infectious manifestation of this condition. In addition to the well-recognized "classic" features of this disease, several unusual manifestations are being recognized with increasing frequency. We presently review and illustrate the following "atypical" manifestations of PCP: (1) interstitial lung responses that include diffuse alveolar damage, bronchiolitis obliterans, interstitial fibrosis, and lymphoplasmacytic infiltrates; (2) striking localized processes frequently exhibiting granulomatous features; (3) extensive necrosis and cavitation; and (4) extrapulmonary dissemination of the disease. Close clinico-pathologic correlation and attention to roentgenographic detail are invaluable aids in arriving at the correct diagnosis.
authors.affiliation: Department of Pathology, University of Miami School of Medicine, FL 33101.
authors.forename: M J
authors.initials: MJ
authors.lastname: Saldana
authors.forename: J M
authors.initials: JM
authors.lastname: Mones
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000473:pathology; D000818:Animals; D006801:Humans; D008168:Lung / Q000473:pathology* / Q000503:physiopathology; D011020:Pneumonia, Pneumocystis / Q000473:pathology* / Q000503:physiopathology