Dominoes and clocks: the union of two views of the cell cycle.
We review the recent advances in understanding transitions within the cell cycle. These have come from both genetic and biochemical approaches. We discuss the phylogenetic conservation of the mechanisms that induce mitosis and their implications for other transitions in the cell cycle.
Murray
A W
AW
Department of Physiology, School of Medicine, University of California, San Francisco 94143-0448.
Kirschner
M W
MW
D000818:Animals; D002453:Cell Cycle; D005809:Genes, Regulator; D007399:Interphase; D008938:Mitosis; D008954:Models, Biological; D008957:Models, Genetic; D013997:Time Factors