The quinolones.
The molecular basis of activity, chemistry, microbiology, and pharmacology of the new fluoroquinolones is reviewed in this article. Areas of clinical use are analyzed with specific reference to efficacy, development of resistance, and potential for toxicity.
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College of Physicians and Surgeons, Columbia University, New York, New York.
D042462:4-Quinolones; D000890:Anti-Infective Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy; D055598:Chemical Phenomena; D002621:Chemistry; D004347:Drug Interactions; D004352:Drug Resistance, Microbial; D004755:Enterobacteriaceae / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects
D042462:4-Quinolones; D000890:Anti-Infective Agents