Randomized double-blind evaluation of ciprofloxacin and doxycycline for Mediterranean spotted fever.
A study of 43 patients with Mediterranean spotted fever showed that a 2-day course of ciprofloxacin or a 2-day course of doxycycline may be an effective mode of therapy. All patients in both arms of the study were cured; however, doxycycline produced a more rapid defervescence.
Gudiol
F
F
Department of Medicine, Bellvitge Hospital, University of Barcelona, Spain.
Pallares
R
R
Carratala
J
J
Bolao
F
F
Ariza
J
J
Rufi
G
G
Viladrich
P F
PF
D000328:Adult; D002939:Ciprofloxacin / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004318:Doxycycline / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D011897:Random Allocation; D012282:Rickettsia Infections / Q000188:drug therapy*
D002939:Ciprofloxacin; D004318:Doxycycline