title: [Therapy of aging skin].
abstract: The process of involution of aging skin is essentially caused by functional changes progressing as a consequence of the chronic influence of exogenous noxae. Reasonably, prophylaxis should avoid actinic damages, and skin care should be adapted to the changes due to age, which means providing a substitute for cutaneous lipids and stabilizing the hydration of the horny layer. Placebo-controlled studies proved that topical treatment with 0.05% tretinoin can result in the regression of degenerative and precancerous changes of the senile skin caused by chronic exposure to UVB. However, long-term results remain to be seen.
authors.affiliation: Hautklinik der Städt, Kliniken Dortmund.
authors.forename: B E
authors.initials: BE
authors.lastname: Roeser
authors.forename: J
authors.initials: J
authors.lastname: Budde
authors.forename: H
authors.initials: H
authors.lastname: Tronnier
mesh_terms: D000368:Aged; D004249:DNA Damage; D004260:DNA Repair / Q000187:drug effects*; D006801:Humans; D009381:Neoplasms, Radiation-Induced / Q000517:prevention & control; D015595:Skin Aging / Q000187:drug effects*; D012878:Skin Neoplasms / Q000517:prevention & control; D014212:Tretinoin / Q000008:administration & dosage*
chemical_list: D014212:Tretinoin
vernacular_title: Therapie der Altershaut.