title: [Stereoradiotherapy of small brain lesions].
abstract: Stereoradiotherapy is the stereotaxy guided high-dose irradiation of small (less than 3 cm) intracerebral lesions. Its aim is to induce necrosis or sclerosis inside the target volume. Several techniques permit us to obtain a steep dose gradient between the lesion and the adjacent healthy cerebral parenchyma. They use minibeams (diameter less than 3 cm) of different types of radiations: protons (Kjellberg from Harvard, since 1962); gamma rays of cobalt 60 (Leksell from Stockholm, since 1968); and X-rays from a linear accelerator (Betti from Buenos-Aires, since 1982). The most commonly treated lesions are arterio-venous malformations, hypophyseal adenomas and low grade parenchymatous tumors. The stereotaxic technique is the only means by which to insure that these high dose irradiations, administered in a single session, are actually delivered to the small lesions situated in the cerebral parenchyma.
authors.affiliation: Service de Radiothérapie B, Hôpital Tenon, Paris.
authors.forename: M
authors.initials: M
authors.lastname: Schlienger
authors.forename: D
authors.initials: D
authors.lastname: Lefkopoulos
authors.forename: C
authors.initials: C
authors.lastname: Krzisch
mesh_terms: D000236:Adenoma / Q000532:radiotherapy; D001918:Brachytherapy / Q000379:methods; D001927:Brain Diseases / Q000532:radiotherapy*; D001932:Brain Neoplasms / Q000532:radiotherapy; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000532:radiotherapy; D010910:Pituitary Irradiation; D010911:Pituitary Neoplasms / Q000532:radiotherapy; D011879:Radiotherapy Dosage; D013238:Stereotaxic Techniques; D014964:X-Ray Therapy
chemical_list: D003037:Cobalt Radioisotopes
vernacular_title: Stéréoradiothérapie des petites lésions encéphaliques.