title: Increase of neuropeptide Y-like immunoreactivity in the paraventricular nucleus of fasting rats.
abstract: The paraventricular nucleus (PVH) of the hypothalamus is a key region for the control of food intake. It presents a very high neuropeptide Y (NPY)-like positive innervation. In this paper we have studied the modifications of NPY-positive innervation in the PVH of 72 h starved rats vs control rats by means of semiquantitative immunocytochemistry. We observed a significant increase of NPY-like immunoreactivity in fasting rats. This result suggests a physiological role of NPY in the food intake regulation at the PVH level.
authors.affiliation: Institute of Human Physiology, Cagliari, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Calzá
authors.forename: L
authors.initials: L
authors.lastname: Giardino
authors.forename: N
authors.initials: N
authors.lastname: Battistini
authors.forename: M
authors.initials: M
authors.lastname: Zanni
authors.forename: S
authors.initials: S
authors.lastname: Galetti
authors.forename: F
authors.initials: F
authors.lastname: Protopapa
authors.forename: A
authors.initials: A
authors.lastname: Velardo
mesh_terms: D000818:Animals; D005215:Fasting; D005455:Fluorescent Antibody Technique; D008297:Male; D009478:Neuropeptide Y / Q000378:metabolism*; D010286:Paraventricular Hypothalamic Nucleus / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D009478:Neuropeptide Y