Physical and histomorphological characteristics of iliac crest bone differ according to the grade of osteoarthritis at the hand.
The amount of cortical and trabecular bone was studied in 32 iliac crest necropsy specimens from women 60-75 years of age and examined according to the grade of osteoarthritis. Three different methods to evaluate bone mass were used: dual photon absorptiometry, physical assessment according to Archimedes' principle, and histomorphometry. Patients were divided into groups--with or without osteoarthritis--according to the presence of osteoarthritis on hand x rays. A significantly increased amount of cortical and trabecular bone mass was found in those who had osteoarthritis at the hands. Percent pure/crude bone volume and trabecular width were found to be increased with osteoarthritic grade, indicating that primary osteoarthritis is probably part of a generalized bone disease.
Gevers
G
G
Arthritis and Metabolic Bone Disease Research Unit, K. U. Leuven, U.Z. Pellenberg, Belgium.
Dequeker
J
J
Geusens
P
P
Nyssen-Behets
C
C
Dhem
A
A
D015502:Absorptiometry, Photon; D000368:Aged; D015519:Bone Density; D005260:Female; D006225:Hand; D006652:Histological Techniques; D006801:Humans; D007085:Ilium / Q000032:analysis / Q000473:pathology*; D008875:Middle Aged; D010003:Osteoarthritis / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*