title: Laser trabeculoplasty versus medication treatment as primary therapy for glaucoma.
abstract: The first-year results of a 5-year prospective randomized follow-up study on 39 glaucoma patients, of whom 19 patients received laser trabeculoplasty and 20 patients medication therapy as primary treatment of their newly detected open-angle glaucoma, are presented. The optic disc changes were recorded by measuring the magnification corrected neuroretinal rim area from stereoscopic optic disc photographs and the visual field changes with an automated perimeter. There were no statistically significant differences in success rate, intraocular pressure reduction, and optic disc or visual field changes between the two groups during the first year of follow-up. In half of the laser treated patients the intraocular pressure was below 22 mmHg without medication treatment. Many patients in the medication group required frequent modifications of their therapy. Laser trabeculoplasty has an important role as primary therapy in glaucoma.
authors.affiliation: Department of Ophthalmology, University of Oulu, Finland.
authors.forename: A
authors.initials: A
authors.lastname: Tuulonen
authors.forename: J
authors.initials: J
authors.lastname: Koponen
authors.forename: H I
authors.initials: HI
authors.lastname: Alanko
authors.forename: P J
authors.initials: PJ
authors.lastname: Airaksinen
mesh_terms: D000086:Acetazolamide / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D006801:Humans; D007429:Intraocular Pressure; D053685:Laser Therapy; D010862:Pilocarpine / Q000627:therapeutic use*; D011446:Prospective Studies; D011897:Random Allocation; D013999:Timolol / Q000627:therapeutic use*; D014130:Trabeculectomy; D014794:Visual Fields
chemical_list: D010862:Pilocarpine; D013999:Timolol; D000086:Acetazolamide