[The eosinophil--the human blood cell superaffined to endotoxin].
With the help of immunofluorescent diagnostic system (specific immunoglobulins against glycolipid of S. minnesota Re-595) has been shown to permit the detection of endotoxin into eosinophil. Statistically significant differences in the occurrence of endotoxin in eosinophils of patients and healthy persons have been revealed. These data allow us to suppose that eosinophils are superaffined endotoxin-interaction cells of the human blood. Eosinopenia may be taken into account as an indirect marker of systemic LPS O-antigen mediated endotoxinemia.
Iakovlev
M Iu
MIu
Kubatiev
A A
AA
Krupnik
A N
AN
Bondarenko
V M
VM
Sudzhan
E V
EV
D000327:Adsorption; D000907:Antibodies, Bacterial / Q000032:analysis; D000915:Antibody Affinity / Q000187:drug effects*; D004731:Endotoxins / Q000097:blood / Q000494:pharmacology*; D004804:Eosinophils / Q000187:drug effects* / Q000276:immunology; D005455:Fluorescent Antibody Technique; D006801:Humans; D008050:Lipid A / Q000097:blood / Q000494:pharmacology; D009154:Mutation; D009504:Neutrophils / Q000187:drug effects / Q000276:immunology; D012486:Salmonella typhimurium / Q000276:immunology
D000907:Antibodies, Bacterial; D004731:Endotoxins; D008050:Lipid A
Eozinofil--superaffinnaia kletka krovi cheloveka k éndotoksinu.