A case of primary intrapulmonary neurilemoma and review of the literature.
In this paper, we present an extremely rare case of a primary intrapulmonary neurogenic tumor, in which localization of S-100 protein, neuron specific gamma-enolase (NSE) and CEA was investigated using immunohistochemical staining. The patient, who was a 39-year-old man, experienced no symptoms; however, a routine chest X-ray revealed a round tumor-like shadow in the infrahilar area of the right lung. As the tumor appeared to be gradually increasing in size, surgery was performed and histopathological examination of the excised tumor revealed it to be a primary intrapulmonary neurilemoma. Immunohistochemical staining demonstrated the presence of S-100 protein in the tumor cells but NSE and CEA were not detected. For the 2 years following his operation, the patient has been in good health and is now under careful observation.
Imaizumi
M
M
Department of Thoracic Surgery, Nagoya University School of Medicine, Japan.
Takahashi
T
T
Niimi
T
T
Uchida
T
T
Abe
T
T
Fukatsu
T
T
D000328:Adult; D002272:Carcinoembryonic Antigen / Q000032:analysis; D006801:Humans; D008175:Lung Neoplasms / Q000032:analysis / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D009442:Neurilemmoma / Q000032:analysis / Q000000981:diagnostic imaging* / Q000473:pathology; D010751:Phosphopyruvate Hydratase / Q000032:analysis; D009418:S100 Proteins / Q000032:analysis; D014057:Tomography, X-Ray Computed
D002272:Carcinoembryonic Antigen; D009418:S100 Proteins; D010751:Phosphopyruvate Hydratase