title: Arteriotracheal fistula in patients treated for lymphoma.
abstract: Exsanguinating hemorrhage is an unusual cause of death in patients who are being treated for neoplasms. We report two cases of adolescents with mediastinal non-Hodgkin's lymphoma who each developed a fistula between the right brachiocephalic trunk and the trachea following mediastinal irradiation and systemic chemotherapy. During the hospital course, the patients had each suffered a respiratory arrest and undergone difficult endotracheal intubation. The tracheal ulcerations at the fistula sites were unsuspected prior to autopsy.
authors.affiliation: Department of Pathology, Harbor-UCLA Medical Center, Torrance 90509.
authors.forename: P S
authors.initials: PS
authors.lastname: Dickman
authors.forename: E
authors.initials: E
authors.lastname: Nussbaum
authors.forename: J Z
authors.initials: JZ
authors.lastname: Finkelstein
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016122:Brachiocephalic Trunk / Q000473:pathology*; D001999:Bronchoscopy / Q000009:adverse effects; D003131:Combined Modality Therapy; D005402:Fistula / Q000209:etiology* / Q000473:pathology; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D007442:Intubation, Intratracheal / Q000009:adverse effects; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy; D008297:Male; D011832:Radiation Injuries / Q000473:pathology; D014133:Tracheal Diseases / Q000209:etiology* / Q000473:pathology