Clinical experience with ciprofloxacin: analysis of a multicenter study.
In a multicenter study of 90 patients treated with ciprofloxacin (mean daily dosage, 936 mg per day; mean duration of treatment, 9.7 days) for a variety of infections, 42 were microbiologically proven. For one case the outcome of therapy was unknown. Of the 41 reported outcomes bacteriologic cure resulted in 92.7%, improvement in 7.3% of cases. Clinical cure equaled 88.4%, while improvement was 9.3%. Failure was reported in 2.3% of cases. A total of 14 infections were classified as chronic. Overall, there were 9/90 (10%) adverse reactions. Six were classified as definitely related to therapy. Therapy with ciprofloxacin was discontinued in four (4.4%) patients because of adverse effects.
Hines
C H
CH
Bordelon
J Y
JY
Jens
D K
DK
Le
C V
CV
McManus
L J
LJ
Spurlock
W M
WM
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001424:Bacterial Infections / Q000188:drug therapy*; D002939:Ciprofloxacin / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic
D002939:Ciprofloxacin