title: Effect of insulin on the production of interleukin 2 by T lymphocytes.
abstract: The effect of insulin on interleukin 2 (IL-2) production was investigated. The results showed that insulin alone did not stimulate the resting T lymphocytes to produce IL-2, but enhanced the production of IL-2 by T lymphocytes and interleukin 1 (IL-1) by macrophages in the presence of lectin. Insulin augmented the response of T lymphocytes to IL-1 in the presence of Con A. The peak time of IL-2 production was not affected by insulin.
authors.forename: Y
authors.initials: Y
authors.lastname: Luo
authors.forename: Z H
authors.initials: ZH
authors.lastname: Feng
authors.forename: R D
authors.initials: RD
authors.lastname: Wang
authors.forename: Z C
authors.initials: ZC
authors.lastname: Chen
mesh_terms: D000818:Animals; D006801:Humans; D007328:Insulin / Q000494:pharmacology*; D007375:Interleukin-1 / Q000096:biosynthesis; D007376:Interleukin-2 / Q000096:biosynthesis*; D008264:Macrophages / Q000378:metabolism; D051379:Mice; D008810:Mice, Inbred C57BL; D013601:T-Lymphocytes / Q000378:metabolism*
chemical_list: D007328:Insulin; D007375:Interleukin-1; D007376:Interleukin-2