Activated oxygen mediates the antimalarial activity of qinghaosu.
Meshnick
S R
SR
City University of New York Medical School, NY 10031.
Tsang
T W
TW
Lin
F B
FB
Pan
H Z
HZ
Chang
C N
CN
Kuypers
F
F
Chiu
D
D
Lubin
B
B
D000818:Animals; D000962:Antimalarials / Q000494:pharmacology*; D037621:Artemisinins; D000077332:Artesunate; D001205:Ascorbic Acid / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D004912:Erythrocytes / Q000187:drug effects* / Q000469:parasitology; D005609:Free Radicals; D005978:Glutathione / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D015227:Lipid Peroxidation / Q000187:drug effects; D010963:Plasmodium falciparum / Q000187:drug effects*; D012717:Sesquiterpenes / Q000494:pharmacology*
D000962:Antimalarials; D037621:Artemisinins; D005609:Free Radicals; D012717:Sesquiterpenes; D000077332:Artesunate; C031327:artemisinin; D005978:Glutathione; D001205:Ascorbic Acid