title: Pirprofen in the treatment of sports injuries.
abstract: Patients with sports injuries were treated with pirprofen, a non-steroidal anti-inflammatory drug, in two separate studies. In the single centre study, 39 athletes were treated with 1000 mg/day pirprofen for 2 weeks. In the multicentre study, a further 80 athletes were treated with a variable dosage (600-1200 mg/day) until the disappearance of symptoms, but for no longer than 2 weeks. Efficacy was considered excellent or good in 99/119 (83%) of the patients treated. The clinical variables of pain and mobility significantly (P less than 0.05) improved after 1 week of treatment. Tolerability was satisfactory, the main side-effects involving the gastro-intestinal tract.
authors.affiliation: Centre of Sports Traumatology, G. Pini Hospital, Milan, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Ventura
authors.forename: P
authors.initials: P
authors.lastname: Volpi
authors.forename: F
authors.initials: F
authors.lastname: Braconaro
authors.forename: E
authors.initials: E
authors.lastname: Porretti
authors.forename: V
authors.initials: V
authors.lastname: Azzolini
authors.forename: E
authors.initials: E
authors.lastname: Giani
authors.forename: U
authors.initials: U
authors.lastname: Garagiola
authors.forename: V
authors.initials: V
authors.lastname: Maresca
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D001265:Athletic Injuries / Q000188:drug therapy* / Q000503:physiopathology; D002908:Chronic Disease; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009068:Movement; D015337:Multicenter Studies as Topic; D010146:Pain / Q000188:drug therapy*; D010666:Phenylpropionates / Q000627:therapeutic use*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D010666:Phenylpropionates; C008924:pirprofen