title: The contribution of HLA to rheumatoid arthritis.
abstract: The contribution of genes within the major histocompatibility complex to rheumatoid arthritis has been calculated (Rotter & Landaw 1984). Separate data from hospital- and population-based studies of monozygotic twin concordance rates and sibling recurrence risks have been used, along with material from published haplotype-sharing studies. Using either source of information gives the same result, a contribution of 37%.
authors.affiliation: Department of Rheumatology, Royal Victoria Infirmary, Newcastle University, Newcastle-upon-Tyne, England.
authors.forename: C M
authors.initials: CM
authors.lastname: Deighton
authors.forename: D J
authors.initials: DJ
authors.lastname: Walker
authors.forename: I D
authors.initials: ID
authors.lastname: Griffiths
authors.forename: D F
authors.initials: DF
authors.lastname: Roberts
mesh_terms: D001172:Arthritis, Rheumatoid / Q000235:genetics*; D004200:Diseases in Twins; D005190:Family; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D014430:Twins, Monozygotic
chemical_list: D006680:HLA Antigens