Zygote intrafallopian transfer as a successful treatment for unexplained infertility.
This study describes the zygote intrafallopian transfer treatment in patients with unexplained infertility. After retrieval, the oocytes were inseminated with 80,000 progressive motile sperm cells per milliliter. If fertilization occurred, a maximum of three zygotes were replaced by laparoscopy in the fimbrial end of one healthy fallopian tube. A pregnancy rate of 48.1% per zygote intrafallopian transfer replacement was obtained. Seventeen pregnancies are actually ongoing, two patients delivered, and seven patients miscarried. Even after replacing a maximum of three zygotes, there were 6 twin and 2 triplet pregnancies.
Devroey
P
P
Center for Reproductive Medicine, Vrije Universiteit Brussel, Belgium.
Staessen
C
C
Camus
M
M
De Grauwe
E
E
Wisanto
A
A
Van Steirteghem
A C
AC
D000328:Adult; D004622:Embryo, Mammalian; D005187:Fallopian Tubes; D005260:Female; D005615:Freezing; D006801:Humans; D007246:Infertility / Q000628:therapy*; D011247:Pregnancy; D011309:Preservation, Biological; D012099:Reproductive Techniques; D015053:Zygote / Q000637:transplantation*