Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box.
The TATA sequence-binding factor TFIID plays a central role both in promoter activation by RNA polymerase II and other common initiation factors, and in promoter regulation by gene-specific factors. The sequence of yeast TFIID, which seems to be encoded by a single gene, contains interesting structural motifs that are possibly involved in these functions, and is similar to sequences of bacterial sigma factors.
Horikoshi
M
M
Laboratory of Biochemistry and Molecular Biology, Rockefeller University, New York, New York 10021.
Wang
C K
CK
Fujii
H
H
Cromlish
J A
JA
Weil
P A
PA
Roeder
R G
RG
D000595:Amino Acid Sequence; D001483:Base Sequence; D015825:Chromosomes, Fungal; D003001:Cloning, Molecular; D004271:DNA, Fungal / Q000235:genetics; D015870:Gene Expression; D005796:Genes; D005800:Genes, Fungal; D008969:Molecular Sequence Data; D011401:Promoter Regions, Genetic; D011485:Protein Binding; D012333:RNA, Messenger / Q000032:analysis / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D035362:Transcription Factor TFIID; D014157:Transcription Factors / Q000235:genetics* / Q000378:metabolism; D014158:Transcription, Genetic
D004271:DNA, Fungal; D012333:RNA, Messenger; D035362:Transcription Factor TFIID; D014157:Transcription Factors