title: Familial translocation t(9;16).
abstract: We report a female with a deletion of 9p and concomitant duplication of 16q [46,XX,-9,+der(9),t(9;16)(p24;q13)]. Parental chromosome analysis showed a balanced maternal translocation [46,XX,t(9;16)(p24;q13)]. Three other cases of translocations involving chromosomes 9 and 16 have been reported, one of them with identical breakpoints. A review of published reports of deletion 9p and duplication 16q is presented, and a comparison is made with previously described cases.
authors.affiliation: Southwest Biomedical Research Institute, Scottsdale, Arizona 85251.
authors.forename: C
authors.initials: C
authors.lastname: Dowman
authors.forename: D
authors.initials: D
authors.lastname: Lockwood
authors.forename: J
authors.initials: J
authors.lastname: Allanson
mesh_terms: D000015:Abnormalities, Multiple / Q000235:genetics* / Q000473:pathology; D002871:Chromosome Banding; D002872:Chromosome Deletion; D002885:Chromosomes, Human, Pair 16; D002899:Chromosomes, Human, Pair 9; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D005810:Multigene Family; D014178:Translocation, Genetic