Recruitment in the Hypertension Prevention trial. Hypertension Prevention Trial Research Group.
The Hypertension Prevention Trial (HPT) was a randomized, controlled, multicenter (four clinics, four resource centers) trial designed to test the feasibility of achieving and sustaining dietary changes in the intake of calories, sodium, and potassium and to assess the effect of those changes on blood pressure in a normotensive population. The trial involved 841 men and women (plus a test cohort of 78) who, at the first baseline (BL) examination were in the age range of 25-49 years and had diastolic blood pressure (DBP) greater than or equal to 76 but less than 100 mm Hg (average of two readings), and at the examination prior to randomization (BL 2), had DBP greater than or equal to 78 but less than 90 mm Hg (also averaged). Participants were randomly assigned to a control treatment group (no dietary counseling) or to one of four dietary treatment groups involving counseling designed to reduce calorie intake, reduce sodium intake, reduce sodium and calorie intake, and reduce sodium and increase potassium intake. This chapter describes the process of recruiting participants for the trial. Methods used to identify and contact study participants are presented. Details of the steps involved in the recruitment process and strategies for reducing costs are discussed.
Borhani
N O
NO
Johns Hopkins School of Hygiene and Public Health, Department of Epidemiology, Baltimore, Md. 21205.
Tonascia
J
J
Schlundt
D G
DG
Prineas
R J
RJ
Jefferys
J L
JL
D000328:Adult; D001294:Attitude to Health; D004608:Eligibility Determination / Q000592:standards*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000178:diet therapy / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D010349:Patient Compliance; D010358:Patient Participation / Q000191:economics / Q000379:methods*; D016032:Randomized Controlled Trials as Topic; D012016:Reference Values; D012494:Sampling Studies