[An autopsied case of malignant lymphoma of the pancreas with an elevation of the serum Ca 19-9 level].
A 37-year-old male was admitted to hospital because of a right hypochondrial pain and icterus. His physical examination showed hepatosplenomegaly, and the laboratory findings demonstrated abnormal hepatic and pancreatic functions. A CT examination revealed a large mass of a low density in the pancreas head and tail. Further, an immunological study revealed that the patients serum Ca 19-9 level was elevated, but that the CEA and AFP levels were normal. Both the pathological and cytological examinations, however, did not indicate a malignancy of the pancreas. The patient subsequently developed uremia, a hemorrhagic tendency, and then died. An autopsy confirmed a pancreatic tumor which occupied the head of pancreas. Histologically, the tumor contained round cells with scanty cytoplasms and showed a sarcomatous pattern. An immunohistochemical study showed that the LCA, MB-1, and the LN-1 for B cell markers were positive, while the MT-1 for T cells was negative. The case illustrates a malignant lymphoma of the pancreas which demonstrated a serum Ca 19-9 elevation.
Sasaki
T
T
1st Dept. of Int. Med., Aichi Medical Univ.
Inagaki
T
T
Katoh
K
K
Ikeda
H
H
Itoh
G
G
D000328:Adult; D000954:Antigens, Surface / Q000032:analysis; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000378:metabolism*; D001402:B-Lymphocytes / Q000276:immunology; D006801:Humans; D007124:Immunoenzyme Techniques; D008223:Lymphoma / Q000097:blood / Q000276:immunology* / Q000473:pathology; D008297:Male; D010190:Pancreatic Neoplasms / Q000097:blood / Q000276:immunology* / Q000473:pathology
D000954:Antigens, Surface; D015295:Antigens, Tumor-Associated, Carbohydrate