[Use of clonidine in the prevention of alcohol withdrawal syndrome].
Clonidine, an effective antihypertensive drug acting on central presynaptic alpha 2-adrenoreceptors, is commonly used in opiate withdrawal. There is recent evidence of advantages in using clonidine also in alcohol withdrawal. The results of a randomized study on 44 alcoholics, admitted without withdrawal symptoms, are shown. The alcohol withdrawal syndrome appeared in 50% of the patients in the placebo group and in 9% of the clonidine treated patients. Clonidine is an effective tool in the hospital preventive treatment of alcohol withdrawal.
Mondavio
M
M
Regione Piemonte, U.S.S.L., Divisione di Medicina Generale.
Ghiazza
G F
GF
D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D003000:Clonidine / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D000431:Ethanol / Q000009:adverse effects*; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D011897:Random Allocation; D013375:Substance Withdrawal Syndrome / Q000517:prevention & control*
D000431:Ethanol; D003000:Clonidine
L'impiego della clonidina nella prevenzione della sindrome da astinenza alcolica (S.A.A.).