title: Base substitutions in the 5' non-coding regions of two naturally occurring yeast invertase structural SUC genes cause strong differences in specific invertase activities.
abstract: Gene SUC4 produced about four fold more invertase activity than did gene SUC5. However, these genes differ in only three positions located in the 5' non-coding region. The difference in gene expression between SUC4 and SUC5 must be due to the G to A transition (position-497) and/or the C to T transition (position -460) in the upstream activator sequences. The sequence TACAAA present in SUC5 can play the same role than the TATAAA box of SUC4.
authors.affiliation: Institut für Mikrobiologie, Technische Hochschule Darmstadt, Federal Republic of Germany.
authors.forename: A
authors.initials: A
authors.lastname: Parets-Soler
mesh_terms: D000241:Adenosine / Q000235:genetics; D001483:Base Sequence; D004271:DNA, Fungal / Q000235:genetics; D004274:DNA, Recombinant; D005786:Gene Expression Regulation; D005800:Genes, Fungal; D006026:Glycoside Hydrolases / Q000235:genetics*; D006151:Guanosine / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000201:enzymology / Q000235:genetics*; D014170:Transformation, Genetic; D043324:beta-Fructofuranosidase
chemical_list: D004271:DNA, Fungal; D004274:DNA, Recombinant; D006151:Guanosine; D006026:Glycoside Hydrolases; D043324:beta-Fructofuranosidase; D000241:Adenosine