title: Drug-induced acute pancreatitis. A critical review.
abstract: Acute pancreatitis has a high morbidity and significant mortality. Among its many causes ethanol is pre-eminent, but many other drugs have also been incriminated. This article begins with a definition of the mechanisms, pathogenesis and clinical features of acute pancreatitis; it then critically reviews the evidence for drugs, excluding ethanol, as being causative. The drugs which have been implicated are considered under 3 headings: definite associations, probable associations and unlikely associations. A brief outline of possible treatment, strategies and prognosis associated with acute pancreatitis concludes the article.
authors.affiliation: Department of Surgery, M.R.C. Clinical Research, Centre London, England.
authors.forename: A K
authors.initials: AK
authors.lastname: Banerjee
authors.forename: K J
authors.initials: KJ
authors.lastname: Patel
authors.forename: S L
authors.initials: SL
authors.lastname: Grainger
mesh_terms: D000208:Acute Disease; D000818:Animals; D006801:Humans; D010195:Pancreatitis / Q000139:chemically induced* / Q000503:physiopathology