Amoxycillin/clavulanate prophylaxis for extracorporeal shock wave lithotripsy--a comparative study.
The incidence of urinary tract infection was examined in 181 patients with sterile urine who underwent extracorporeal shock wave lithotripsy (ESWL) as outpatients. The incidence of post operative infection was compared in a prospective randomized trial between patients who received a single prophylactic dose of amoxycillin/clavulanate iv and controls who received no antibiotic. Clinical signs of urinary infection, leucocyturia, positive urine cultures and abnormal ESR and peripheral leucocyte count were found much more frequently in the control than in the prophylactic group. This study has confirmed that even patients free of infection risk factors benefit from antibiotic prophylaxis before ESWL.
Claes
H
H
Department of Urology, Academic Hospital St. Pieter, Leuven, Belgium.
Vandeursen
R
R
Baert
L
L
D000328:Adult; D000368:Aged; D000658:Amoxicillin / Q000627:therapeutic use*; D002969:Clavulanic Acids / Q000627:therapeutic use*; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008096:Lithotripsy; D008297:Male; D008875:Middle Aged; D016032:Randomized Controlled Trials as Topic; D014552:Urinary Tract Infections / Q000209:etiology / Q000517:prevention & control*
D002969:Clavulanic Acids; D000658:Amoxicillin