Long term results of stereotactic endocavitary beta irradiation of craniopharyngioma cysts.
This study concerns 33 pts (age: 3-69 yrs; m: 22) with cystic craniopharyngiomas (36 cysts) treated with stereotactic beta endocavitary irradiation (TRT). Nine patients died (3 days to 36 months after TRT) and one was lost. In 23 the follow-up varied from 12 to 126 months (m: 45 months). The disappearance of 13 cysts was appreciated 5 to 24 months after TRT: no recurrence was observed after 22-126 months (m: 61). A greater than 70% reduction of the cyst volume occurred 3-36 months after TRT and persisted at 12-71 months (m: 35 m). In one patient, the cyst volume increased. Visual acuity improved in more than 50% of survivors, while endocrine disturbances did not change and memory troubles disappeared.
Munari
C
C
Service de Neurochirurgie, Hôpital Sainte-Anne, Paris, France.
Landre
E
E
Musolino
A
A
Turak
B
B
Habert
M O
MO
Chodkiewicz
J P
JP
D000293:Adolescent; D000328:Adult; D000368:Aged; D001918:Brachytherapy; D002648:Child; D002675:Child, Preschool; D003397:Craniopharyngioma / Q000532:radiotherapy*; D005500:Follow-Up Studies; D006801:Humans; D008722:Methods; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000532:radiotherapy*; D013238:Stereotaxic Techniques