title: Immune regulation in IgA nephropathy.
abstract: Regulation in IgA nephropathy (IgA N) has been largely studied. We present in this work our recent data which suggest that an abnormal chemical structure and/or molecular form of serum immunoglobulin A (IgA) might contribute to both the mesangial deposition of IgA and the T cell abnormalities which may in turn deregulate the IgA synthesis.
authors.affiliation: Département de Néphrologie et INSERM U 25, Hôpital Necker, Paris.
authors.forename: R C
authors.initials: RC
authors.lastname: Monteiro
authors.forename: L H
authors.initials: LH
authors.lastname: Noël
authors.forename: A
authors.initials: A
authors.lastname: Chevailler
authors.forename: L
authors.initials: L
authors.lastname: Halbwachs-Mecarelli
authors.forename: P
authors.initials: P
authors.lastname: Lesavre
mesh_terms: D000936:Antigen-Antibody Complex / Q000276:immunology; D005920:Glomerular Mesangium / Q000276:immunology; D005922:Glomerulonephritis, IGA / Q000276:immunology*; D006706:Homeostasis; D006801:Humans; D007109:Immunity; D007070:Immunoglobulin A / Q000096:biosynthesis / Q000276:immunology; D011961:Receptors, Fc / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D000936:Antigen-Antibody Complex; D007070:Immunoglobulin A; D011961:Receptors, Fc