Haem biosynthesis and porphyrias: 50 years in retrospect.
This review deals with haem biosynthesis and the porphyrias and, as indicated by the title, it is largely retrospective, and discusses mainly those aspects relevant to the author's own work. An attempt is also made to show how modern concepts have developed in these inter-related fields and to illustrate their dependence upon different phases of experimental investigation.
Rimington
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Institute for Cancer Research, Norwegian Radium Hospital, Montebello, Oslo.
D001671:Biochemistry / Q000266:history*; D006418:Heme / Q000096:biosynthesis*; D049673:History, 20th Century; D006801:Humans; D008954:Models, Biological; D011162:Porphobilinogen / Q000378:metabolism*; D011164:Porphyrias / Q000201:enzymology / Q000378:metabolism*; D011166:Porphyrins / Q000378:metabolism*; D012189:Retrospective Studies
D011166:Porphyrins; D006418:Heme; D011162:Porphobilinogen