title: The ribonucleoside diphosphate reductase gene (nrdA) of Escherichia coli carries a repetitive extragenic palindromic (REP) sequence in its 3' structural terminus.
abstract: A computer search for repeated sequences led us to identify five REP (repetitive extragenic palindromic) sequences in the 3'-terminal region of the Escherichia coli ribonucleoside diphosphate reductase gene (nrdA). These REP sequences are located within a putative duplicated DNA region, the first of them being part of the carboxy-terminal coding region of the nrdA gene. This is the first report of a REP sequence within a structural gene and also the first example of a REP sequence apparently generated by DNA duplication.
authors.affiliation: Centro de Investigación sobre Ingeniería Genética y, Biotechnología, Universidad Nacional Autónoma de Mexico, Cuernavaca, Morelos C.P.
authors.forename: E
authors.initials: E
authors.lastname: Merino
authors.forename: F
authors.initials: F
authors.lastname: Bolivar
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D004269:DNA, Bacterial; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics*; D005796:Genes; D005798:Genes, Bacterial; D008969:Molecular Sequence Data; D012091:Repetitive Sequences, Nucleic Acid; D012262:Ribonucleoside Diphosphate Reductase / Q000235:genetics*; D012264:Ribonucleotide Reductases / Q000235:genetics*
chemical_list: D004269:DNA, Bacterial; D012264:Ribonucleotide Reductases; D012262:Ribonucleoside Diphosphate Reductase