Castleman's disease: a well defined histological pattern for a widely divergent clinical spectrum.
If the histological patterns of Castleman's disease are well defined--hyaline vascular type and plasma cell type--, the clinical spectrum is widely divergent, ranging from localised forms cured by surgical ablation to multicentric idiopathic forms requiring systemic therapy; some cases are associated with an acquired immunodeficiency, such as HIV infection. The pathogeny of the disease is discussed.
d'Agay
M F
MF
Laboratoire d'Anatomie Pathologique, Hôpital Saint-Louis, Paris, France.
Miclea
J M
JM
Clauvel
J P
JP
Schaison
G
G
Brocheriou
C
C
D005871:Castleman Disease / Q000145:classification / Q000473:pathology*; D006801:Humans; D006965:Hyperplasia; D008198:Lymph Nodes / Q000473:pathology; D010950:Plasma Cells / Q000473:pathology