title: Transcranial Doppler sonographic studies of cerebral autoregulation in Shy-Drager syndrome.
abstract: A study is reported of mean arterial blood pressure and heart rate in four patients suffering from Shy-Drager syndrome. Blood flow velocity in the middle cerebral artery (MCA) was recorded by transcranial Doppler sonography. Concomitant changes in cerebral blood flow and the effect of cerebral autoregulation were thus examined. During tilt (60 degrees, head up) mean arterial blood pressure decreased by 40 mm Hg or 35%, while MCA blood flow velocity dropped by 14 cm/s or 28% (mean values). The lower percentage reduction in flow velocity may indicate a preserved cerebral autoregulation in central autonomic insufficiency.
authors.affiliation: Abteilung für Neurologie, Universitätskliniken Frankfurt Main, Federal Republic of Germany.
authors.forename: T
authors.initials: T
authors.lastname: Briebach
authors.forename: J
authors.initials: J
authors.lastname: Laubenberger
authors.forename: P A
authors.initials: PA
authors.lastname: Fischer
mesh_terms: D000368:Aged; D001342:Autonomic Nervous System Diseases / Q000503:physiopathology*; D001783:Blood Flow Velocity; D001794:Blood Pressure; D002560:Cerebrovascular Circulation; D005260:Female; D006339:Heart Rate; D006706:Homeostasis; D006801:Humans; D008297:Male; D008875:Middle Aged; D012791:Shy-Drager Syndrome / Q000503:physiopathology*; D014463:Ultrasonography