[Effect of pasta ulmi on malaria parasites].
The extract of Pasta ulmi was examined in vivo and in vitro for antimalaria effect. During animal experiments lipophil extract appeared to have a stronger effect than whole extract, whereas the water diluted extract had no therapeutic effect. In the cell culture the isolated fraction of lipophil extract C1, C2 and C4 showed no inhibitory effect on P. falciparum, but the fraction C0 and C3 with a concentration of 10 micrograms/ml medium demonstrated a totally parasiticidal effect on parasites on the 5th day of culture.
Zhao
C X
CX
D000818:Animals; D000962:Antimalarials; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use; D008288:Malaria / Q000188:drug therapy*; D051379:Mice; D010963:Plasmodium falciparum / Q000187:drug effects*
D000962:Antimalarials; D004365:Drugs, Chinese Herbal
Untersuchungen zur Wirkung von Pasta ulmi auf Malariaparsiten.