[Experimental atherogenesis: early wall changes in the cynomolgus monkey].
The early parietal changes in atherogenesis are characterized by: Increase of endothelial permeability with proteoglycans and L.D.L. storage. Lysis of internal elastic lamellae. Penetration into sub-endothelial space of monocytes macrophages and transformation into foam cells. Parietal fibrosis and proliferating smooth muscle cells play a role in the extension of lipid deposit.
Bouissou
H
H
Julian
M
M
Pieraggi
M T
MT
Thiers
J C
JC
Aouidet
A
A
Kokolo
J
J
Delsol
G
G
D000818:Animals; D001161:Arteriosclerosis / Q000378:metabolism / Q000473:pathology*; D004730:Endothelium, Vascular / Q000378:metabolism / Q000473:pathology*; D008252:Macaca fascicularis
Athérogénèse expérimentale: modifications pariétales précoces chez le singe cynomolgus.