DNA homology between Candida albicans strains: evidence to justify the synonymous status of C. stellatoidea.
Genetic relatedness between strains of C. albicans and C. stellatoidea was studied by measuring G + C content and overall sequence homology. G + C contents determined by high-performance liquid chromatography were 32.6 to 34.2% for 26 strains of C. albicans and 33.0 to 33.9% for eight strains of C. stellatoidea. DNA-DNA hybridization with two C. albicans and two C. stellatoidea probes revealed that all 34 test strains formed a single cluster in which the extents of hybridization with the heterologous probes ranged between 77.9 and 105.6% of those with the homologous probes. These results give support to the unification of C. albicans and C. stellatoidea into a single species.
Kamiyama
A
A
Department of Microbiology, School of Dentistry, Kagoshima University, Japan.
Niimi
M
M
Tokunaga
M
M
Nakayama
H
H
D001482:Base Composition; D002175:Candida / Q000145:classification / Q000235:genetics*; D002176:Candida albicans / Q000145:classification / Q000235:genetics*; D002851:Chromatography, High Pressure Liquid; D004271:DNA, Fungal / Q000032:analysis*; D009693:Nucleic Acid Hybridization; D012689:Sequence Homology, Nucleic Acid
D004271:DNA, Fungal