Review: pharmacologic control of wound healing in glaucoma filtration surgery.
An integrated understanding of the wound healing process, pharmacological agents, and surgical techniques are required for comprehensive treatment of wound healing in glaucoma filtration surgery. More well controlled basic and clinical studies are required to clarify the existing ambiguities in the selection of proper pharmacological agents, dosage, timing, and method of delivery. The most promising treatment modalities may be combination drug therapy and the use of bioerodible compounds for a sustained and localized delivery system.
Tahery
M M
MM
Jules Stein Eye Institute, Department of Ophthalmology, UCLA School of Medicine.
Lee
D A
DA
D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000494:pharmacology; D004333:Drug Administration Routes; D005343:Fibrinolytic Agents / Q000494:pharmacology; D005347:Fibroblasts / Q000187:drug effects; D005374:Filtration; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D013514:Surgical Procedures, Operative / Q000379:methods; D014945:Wound Healing / Q000187:drug effects*
D000893:Anti-Inflammatory Agents; D000970:Antineoplastic Agents; D005343:Fibrinolytic Agents