title: Managing chemotherapy-related nausea and vomiting: the state of the art.
abstract: The consequences of inadequately controlled chemotherapy-related nausea and vomiting range from minor discomfort to dose-limiting toxicity. Physical complications may occur secondary to protracted nausea and emesis. Furthermore, patient discomfort may be reflected in altered quality of life or noncompliance with therapy. As a primary caregiver, the nurse takes an active role in collaborating with the physician to prevent and/or minimize these side effects and their sequelae. An understanding of the patterns, mechanisms, and risk of chemotherapy-related nausea and vomiting is crucial to providing optimal patient care. Concepts of drug therapy are emphasized as the cornerstone of antiemetic management.
authors.forename: R
authors.initials: R
authors.lastname: Wickham
mesh_terms: D000932:Antiemetics / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D006801:Humans; D009325:Nausea / Q000139:chemically induced / Q000188:drug therapy* / Q000451:nursing; D014839:Vomiting / Q000139:chemically induced / Q000188:drug therapy* / Q000451:nursing
chemical_list: D000932:Antiemetics; D000970:Antineoplastic Agents