title: MHC class II invariant chains in antigen processing and presentation.
abstract: Most protein antigens cannot elicit a T-cell response unless they are processed to peptides, which are then presented to T lymphocytes by surface MHC class II molecules. Recent evidence supports an essential role of the invariant chain associated with class II MHC polypeptides in antigen processing.
authors.forename: N
authors.initials: N
authors.lastname: Koch
authors.forename: J
authors.initials: J
authors.lastname: Lipp
authors.forename: U
authors.initials: U
authors.lastname: Pessara
authors.forename: K
authors.initials: K
authors.lastname: Schenck
authors.forename: C
authors.initials: C
authors.lastname: Wraight
authors.forename: B
authors.initials: B
authors.lastname: Dobberstein
mesh_terms: D000941:Antigens / Q000276:immunology*; D015870:Gene Expression / Q000502:physiology*; D008285:Major Histocompatibility Complex / Q000502:physiology*
chemical_list: D000941:Antigens