title: [The role of fibronectin in the streptococcal adhesion process].
abstract: The work shows that fibronectin obtained from human plasma is capable of binding with streptococci of different groups with almost equal effectiveness. Fibronectin bound to bacterial cells inhibits the adhesion of group A streptococci onto vaginal cells, but it produces no effect on the adhesion of group B streptococci. The binding constant of fibronectin 125I is equal to 10(6) -M-1, which indicates that the level of the specificity of interaction is not sufficiently high.
authors.forename: L V
authors.initials: LV
authors.lastname: Lyzlova
authors.forename: B L
authors.initials: BL
authors.lastname: Voĭtsekhovskiĭ
authors.forename: K B
authors.initials: KB
authors.lastname: Grabovskaia
authors.forename: A A
authors.initials: AA
authors.lastname: Totolian
mesh_terms: D001422:Bacterial Adhesion / Q000187:drug effects*; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D004848:Epithelium / Q000378:metabolism / Q000382:microbiology; D005260:Female; D005353:Fibronectins / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D009154:Mutation; D011485:Protein Binding / Q000187:drug effects; D013292:Streptococcus agalactiae / Q000378:metabolism / Q000472:pathogenicity*; D013297:Streptococcus pyogenes / Q000378:metabolism / Q000472:pathogenicity*; D014621:Vagina / Q000378:metabolism / Q000382:microbiology
chemical_list: D005353:Fibronectins
vernacular_title: Rol' fibronektina v protsesse adgezii streptokokkov.