Interstitial pneumonitis in human visceral leishmaniasis.
The involvement of the lung in 13 cases of human visceral leishmaniasis was studied. Interstitial pneumonitis with mononuclear cells was found in 76.8% of the cases; 53.8% also had foci of septal fibrosis. Leishmania were seen within macrophages in 3 cases only. However, all 10 interstitial pneumonitis cases showed PAP-positive material using specific L. donovani (MHOM/BR/72/LD 46) antiserum. 3 cases with no interstitial pneumonitis were PAP-negative. A short discussion about clinical aspects and the course of the disease is presented.
Duarte
M I
MI
Laboratório de Patologia de Moléstias Infecciosas, Pathology Department, University of São Paulo Medical School, Brazil.
da Matta
V L
VL
Corbett
C E
CE
Laurenti
M D
MD
Chebabo
R
R
Goto
H
H
D001344:Autopsy; D006801:Humans; D007124:Immunoenzyme Techniques; D007898:Leishmaniasis, Visceral / Q000473:pathology*; D008168:Lung / Q000473:pathology*; D011658:Pulmonary Fibrosis / Q000473:pathology*