title: Physical and histomorphological characteristics of iliac crest bone differ according to the grade of osteoarthritis at the hand.
abstract: The amount of cortical and trabecular bone was studied in 32 iliac crest necropsy specimens from women 60-75 years of age and examined according to the grade of osteoarthritis. Three different methods to evaluate bone mass were used: dual photon absorptiometry, physical assessment according to Archimedes' principle, and histomorphometry. Patients were divided into groups--with or without osteoarthritis--according to the presence of osteoarthritis on hand x rays. A significantly increased amount of cortical and trabecular bone mass was found in those who had osteoarthritis at the hands. Percent pure/crude bone volume and trabecular width were found to be increased with osteoarthritic grade, indicating that primary osteoarthritis is probably part of a generalized bone disease.
authors.affiliation: Arthritis and Metabolic Bone Disease Research Unit, K. U. Leuven, U.Z. Pellenberg, Belgium.
authors.forename: G
authors.initials: G
authors.lastname: Gevers
authors.forename: J
authors.initials: J
authors.lastname: Dequeker
authors.forename: P
authors.initials: P
authors.lastname: Geusens
authors.forename: C
authors.initials: C
authors.lastname: Nyssen-Behets
authors.forename: A
authors.initials: A
authors.lastname: Dhem
mesh_terms: D015502:Absorptiometry, Photon; D000368:Aged; D015519:Bone Density; D005260:Female; D006225:Hand; D006652:Histological Techniques; D006801:Humans; D007085:Ilium / Q000032:analysis / Q000473:pathology*; D008875:Middle Aged; D010003:Osteoarthritis / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*