Nonrestorative sleep and symptoms after a febrile illness in patients with fibrositis and chronic fatigue syndromes.
This review summarizes the physiologic and clinical evidence that shows nonrestorative sleep to be associated with chronic fatigue and diffuse myalgia after a flulike illness. Such a febrile illness may trigger alteration in sleep-wake brain and immune functions in patients with fibrositis or chronic fatigue syndromes.
Moldofsky
H
H
Department of Psychiatry, University of Toronto, ON, Canada.
D015673:Fatigue Syndrome, Chronic / Q000150:complications* / Q000503:physiopathology; D005334:Fever / Q000150:complications* / Q000503:physiopathology; D005356:Fibromyalgia / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D007107:Immune System / Q000503:physiopathology; D007239:Infections / Q000150:complications / Q000503:physiopathology; D009135:Muscular Diseases / Q000503:physiopathology; D010146:Pain; D012890:Sleep; D007319:Sleep Initiation and Maintenance Disorders / Q000150:complications; D012893:Sleep Wake Disorders / Q000150:complications* / Q000503:physiopathology