Sex hormones and autoimmune disease.
Evidence for the influence of sex hormones--androgens, oestrogens and progestogens--on autoimmune disease is reviewed. Androgens and, perhaps, progestogens may protect from autoimmune disease; oestrogens seem to protect from rheumatoid arthritis but to be deleterious in systemic lupus erythematosus.
Schuurs
A H
AH
Organon SDG, Oss, The Netherlands.
Verheul
H A
HA
D000728:Androgens / Q000276:immunology*; D000818:Animals; D001327:Autoimmune Diseases / Q000276:immunology*; D055598:Chemical Phenomena; D002621:Chemistry; D004967:Estrogens / Q000276:immunology*; D006801:Humans; D011372:Progestins / Q000276:immunology*; D012737:Sex Factors; D013329:Structure-Activity Relationship
D000728:Androgens; D004967:Estrogens; D011372:Progestins