title: Brain resuscitation. Medical management and innovations.
abstract: In this article, we have reviewed the pathophysiology and several therapeutic strategies for cerebral ischemia. It seems likely that there will never be simple therapeutic answers to the complex pathophysiology of cerebral ischemia as we now understand it. Ultimate therapies will probably involve combinations of interventions designed to block several ongoing pathophysiologic processes in neuronal death. Progress in this field will likely be slow and difficult.
authors.forename: J R
authors.initials: JR
authors.lastname: Kirsch
authors.forename: M N
authors.initials: MN
authors.lastname: Diringer
authors.forename: C O
authors.initials: CO
authors.lastname: Borel
authors.forename: G K
authors.initials: GK
authors.lastname: Hart
authors.forename: D F
authors.initials: DF
authors.lastname: Hanley
mesh_terms: D000596:Amino Acids / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D002545:Brain Ischemia / Q000503:physiopathology / Q000628:therapy*; D003131:Combined Modality Therapy; D004734:Energy Metabolism; D005609:Free Radicals; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007427:Intracranial Pressure
chemical_list: D000596:Amino Acids; D005609:Free Radicals