Cyto-histological diagnosis on wet smears of neurosurgical biopsies.
Since 1930 the supravital staining of thin smears of small specimens from brain tumors taken at operation has been considered useful. In more recent time this technique has become mandatory in multiple serial stereotactic biopsies because it give consistent support in "real time" to this procedure. Many important features can be considered in the bioptic fragment, such as: morphology, cellularity, specific microscopical structures, regressive processes, necrotic tissues, neoangiogenesis and mixed cellular population. But, for the correct interpretation of these data, a close collaboration among the neurosurgeon, the neuroradiologist and the cytopathologist must be guaranteed.
Allegranza
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Istituto Neurologico C. Besta, Milano, Italy.
D001706:Biopsy; D001921:Brain / Q000166:cytology / Q000473:pathology*; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000648:ultrastructure; D006652:Histological Techniques; D006801:Humans; D013238:Stereotaxic Techniques