Successful treatment of a live cervical pregnancy with methotrexate and folinic acid. A case report.
A case of cervical pregnancy with a fetal pole, fetal cardiac activity and a serum beta-human chorionic gonadotropin level reaching a peak of 60,000 mIU/mL was treated successfully with methotrexate and folinic acid. These criteria have been considered a contraindication to conservative medical management. Serial beta-human chorionic gonadotropin levels and sonography were used to diagnose the pregnancy and monitor therapy. Complications were limited to transient conjunctivitis and blood loss anemia. The patient's fertility potential was preserved.
Kaplan
B R
BR
Department of Obstetrics and Gynecology, Michael Reese Hospital and Medical Center, Pritzker School of Medicine, University of Chicago, IL 60616.
Brandt
T
T
Javaheri
G
G
Scommegna
A
A
D000328:Adult; D002584:Cervix Uteri; D006063:Chorionic Gonadotropin / Q000097:blood; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use*; D008727:Methotrexate / Q000627:therapeutic use*; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy*; D014463:Ultrasonography
D006063:Chorionic Gonadotropin; D002955:Leucovorin; D008727:Methotrexate