Antidepressant effects of right versus left unilateral ECT and the lateralization theory of ECT action.
In a random-assignment, double-blind, controlled comparison of right versus left unilateral ECT in 30 melancholic men, the two methods were not significantly different in overall antidepressant potency, although there was a significantly faster rate of improvement with left unilateral ECT. These results imply that the antidepressant effects of ECT cannot be attributed primarily to right hemisphere mechanisms, as others have postulated.
Abrams
R
R
Department of Psychiatry, University of Health Sciences/Chicago Medical School, IL 60064.
Swartz
C M
CM
Vedak
C
C
D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D003866:Depressive Disorder / Q000523:psychology / Q000628:therapy*; D004311:Double-Blind Method; D004565:Electroconvulsive Therapy / Q000379:methods*; D007839:Functional Laterality; D006801:Humans; D008297:Male; D008875:Middle Aged; D011897:Random Allocation