title: Poly(ether urethane) wound covering with high water vapour permeability compared with conventional tulle gras on split-skin donor sites.
abstract: The experimental poly(ether urethane) (PEU) wound covering with a high water vapour permeance was compared with tulle gras treatment on adjacent areas of the same 20 split-skin donor sites. All patients experienced little or no pain from the PEU-covered areas, while 70 per cent of the patients complained of more pain from the tulle gras-covered areas. The PEU covering did not absorb the wound exudate underneath, neither did it retain wound fluid, but turned the wound exudate into a jelly-like clot layer by allowing a high evaporative water loss from the wound. Tulle gras treatment also prevented wound desiccation, but the exudate was absorbed into the overlaying cotton pads, where it became dry at the outer surface. Microscopy revealed that re-epithelialization occurred at a similar rate under the PEU covering as under tulle gras. In conclusion, the high water vapour permeable PEU wound covering prevents fluid retention, induces clotting of the wound exudate and reduces pain in split-skin donor sites. Tulle gras dressed with gauzes and crêpe bandage prevents wound desiccation, but causes more pain.
authors.affiliation: Department of Histology and Cell Biology, University of Groningen, The Netherlands.
authors.forename: M F
authors.initials: MF
authors.lastname: Jonkman
authors.forename: P
authors.initials: P
authors.lastname: Bruin
authors.forename: A J
authors.initials: AJ
authors.lastname: Pennings
authors.forename: J M
authors.initials: JM
authors.lastname: Coenen
authors.forename: H J
authors.initials: HJ
authors.lastname: Klasen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001458:Bandages; D001672:Biocompatible Materials; D002056:Burns / Q000601:surgery*; D005260:Female; D003368:Gossypium; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000517:prevention & control; D010232:Paraffin; D010539:Permeability; D011140:Polyurethanes; D012867:Skin / Q000473:pathology; D016038:Skin Transplantation; D014867:Water; D014945:Wound Healing
chemical_list: D001672:Biocompatible Materials; D011140:Polyurethanes; C115016:polyetherurethane; D014867:Water; D010232:Paraffin