Synthesis and antifungal activity of some amidrazone derivatives.
The synthesis and in vitro antifungal activity of some pyridincarboxyamidrazone derivatives are described. 2-pyridincarboxyamidrazone derivative (IIa) in comparison with miconazole showed an interesting even if low antimycotic activity.
Vio
L
L
Istituto Di Chimica Farmaceutica, Università Di Trieste, Italy.
Mamolo
M G
MG
Ronsisvalle
G
G
Oliveri
S
S
Grego
A M
AM
D000578:Amidines / Q000138:chemical synthesis / Q000494:pharmacology*; D000935:Antifungal Agents / Q000138:chemical synthesis*; D001234:Aspergillus niger / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D003470:Culture Media; D005658:Fungi / Q000187:drug effects; D005663:Furans / Q000138:chemical synthesis / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D011725:Pyridines / Q000138:chemical synthesis / Q000494:pharmacology*; D013876:Thiophenes / Q000138:chemical synthesis / Q000494:pharmacology; D014249:Trichophyton / Q000187:drug effects
D000578:Amidines; D000935:Antifungal Agents; D003470:Culture Media; D005663:Furans; D011725:Pyridines; D013876:Thiophenes