Some features of the nigrostriatal dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse.
Heikkila
R E
RE
Department of Neurology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, NJ 08854.
Sieber
B A
BA
Manzino
L
L
Sonsalla
P K
PK
D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; D000818:Animals; D003342:Corpus Striatum / Q000187:drug effects / Q000473:pathology*; D004298:Dopamine / Q000378:metabolism*; D051379:Mice; D009498:Neurotoxins / Q000494:pharmacology*; D010302:Parkinson Disease, Secondary / Q000139:chemically induced; D011725:Pyridines / Q000633:toxicity*; D013378:Substantia Nigra / Q000187:drug effects / Q000473:pathology*
D009498:Neurotoxins; D011725:Pyridines; D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; D004298:Dopamine