title: Bowen's disease and internal malignancy. A meta-analysis.
abstract: Bowen's disease frequently has been reported to be associated with internal malignancy, although this association has been extremely controversial. The present study uses the technique of meta-analysis to address this issue by pooling the results of the 12 studies published in the English-language literature that previously have attempted to study this issue. The results indicated no significant association between the two conditions (chi square, 1 d.f., = 0.128, p greater than 0.05, 95% confidence interval = 0.105-0.1503). Clearly, no extensive investigation in patients having Bowen's disease is warranted.
authors.affiliation: Department of Dermatology, University of Minnesota School of Medicine, Minneapolis.
authors.forename: B A
authors.initials: BA
authors.lastname: Lycka
mesh_terms: D001913:Bowen's Disease / Q000150:complications*; D002294:Carcinoma, Squamous Cell / Q000150:complications*; D006801:Humans; D008523:MEDLARS; D015201:Meta-Analysis as Topic; D009317:National Library of Medicine (U.S.); D009369:Neoplasms / Q000150:complications*; D012878:Skin Neoplasms / Q000150:complications; D014481:United States