Fetal diaphragmatic hernia: the value of fetal echocardiography in the prediction of postnatal outcome.
Nineteen pregnancies complicated by fetal congenital diaphragmatic hernia (CDH) referred for fetal echocardiography have been reviewed. Congenital heart disease was diagnosed prenatally in three fetuses; in one of these the pregnancy was terminated, the two other infants died in the neonatal period. The presence of the fetal stomach within the thorax or a hernia/heart area ratio greater than 1.7 was associated with a large diaphragmatic defect. Polyhydramnios was not associated with a poor postnatal outcome. Evidence of cardiac ventricular disproportion before 24 weeks gestation in isolated CDH was associated with 100% mortality. Development of ventricular disproportion during the third trimester was associated with a survival rate of 75%. In three fetuses, all of whom survived, no ventricular disproportion was detected during the third trimester examination.
Crawford
D C
DC
Guy's Hospital, London.
Wright
V M
VM
Drake
D P
DP
Allan
L D
LD
D004452:Echocardiography; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D006330:Heart Defects, Congenital / Q000175:diagnosis*; D006548:Hernia, Diaphragmatic / Q000175:diagnosis; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D011247:Pregnancy; D011296:Prenatal Diagnosis; D011379:Prognosis; D014463:Ultrasonography