Initiation of skin carcinogenesis can occur by induction of carcinogen-specific point mutations in the Harvey-ras gene.
Bailleul
B
B
Beatson Institute for Cancer Research, Bearsden, Glasgow, U.K.
Brown
K
K
Ramsden
M
M
Fee
F
F
Balmain
A
A
D000818:Animals; D002273:Carcinogens; D015500:Chloramphenicol O-Acetyltransferase / Q000235:genetics; D004195:Disease Models, Animal; D011905:Genes, ras; D051379:Mice; D009154:Mutation; D011401:Promoter Regions, Genetic; D011519:Proto-Oncogenes; D012878:Skin Neoplasms / Q000139:chemically induced / Q000235:genetics*; D014158:Transcription, Genetic
D002273:Carcinogens; D015500:Chloramphenicol O-Acetyltransferase