title: [Mammary fibroadenoma showing osseous metaplasia: a case report].
abstract: Discussed is a 33-year-old premenopausal woman who noted a mass in her right breast. On palpation, the tumor was determined as being 3.5 x 2.5 cm in size, well circumscribed, of a firm consistency, and freely movable. Mammography showed a well-defined oval lesion which contained a coarse calcification in the upper external quadrant. An ultrasound study revealed a well-defined oval low echoic lesion with a high echoic portion in the internal echo. The tumor was extirpated and a gross inspection found it to be an ordinary fibroadenoma, 3.2 x 2.5 x 1.5 cm in size. Histologically the lesion was a hyalinized fibroadenoma showing osseous metaplasia. A review of the literature has not revealed cases of a benign breast tumors showing an osseous and/or cartilagenous metaplasia. Notable however is that many reports show mammary osteosarcomas as originating from a fibroadenoma. Thus, this tumor also might have possibly developed into a osteosarcoma.
authors.affiliation: Dept. of Surgery, Hyogo Medical Center for Adults.
authors.forename: Y
authors.initials: Y
authors.lastname: Nishida
authors.forename: N
authors.initials: N
authors.lastname: Kohno
authors.forename: Y
authors.initials: Y
authors.lastname: Furuya
authors.forename: T
authors.initials: T
authors.lastname: Nakatani
authors.forename: S
authors.initials: S
authors.lastname: Kaneko
authors.forename: T
authors.initials: T
authors.lastname: Sashikata
authors.forename: O
authors.initials: O
authors.lastname: Fujiwara
authors.forename: Y
authors.initials: Y
authors.lastname: Saitoh
mesh_terms: D000232:Adenofibroma / Q000175:diagnosis / Q000473:pathology*; D000328:Adult; D001853:Bone Marrow / Q000473:pathology; D001842:Bone and Bones / Q000473:pathology*; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology*; D002114:Calcinosis / Q000473:pathology; D005260:Female; D006801:Humans; D008679:Metaplasia; D010006:Osteoblasts / Q000473:pathology; D012516:Osteosarcoma / Q000473:pathology; D014463:Ultrasonography