Metronidazole, clindamycin, and quinolones.
This article covers well-known agents such as metronidazole that have decades of use for treatment of Trichomonas with newer applications in anaerobic diseases. Clindamycin, also used in treatment in anaerobic infections, is reassessed for its efficacy in treating vaginal infections and possibly with Chlamydia. Quinolones, a new group of agents with their applications in female genital tract and urinary tract infections is reviewed. Specific consideration is given to toxicity of these agents for the practicing obstetrician.
Hammill
H A
HA
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas.
D042462:4-Quinolones; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy*; D002981:Clindamycin / Q000627:therapeutic use*; D005260:Female; D005831:Genital Diseases, Female / Q000188:drug therapy*; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use*; D008826:Microbial Sensitivity Tests; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy*
D042462:4-Quinolones; D000890:Anti-Infective Agents; D008795:Metronidazole; D002981:Clindamycin