Photosensitive annular elastolytic giant cell granuloma with cutaneous amyloidosis.
Annular erythematous indurated plaques with central clearing developed on sun-exposed areas of a diabetic patient. The lesions were aggravated by sun exposure. Histological examination revealed features as described in annular elastolytic giant cell granuloma. In addition, subepidermal amyloid deposits were identified. Though a coincidental occurrence cannot be excluded, a possible pathogenetic relationship between the two conditions is postulated. It is believed that they are caused by actinic damage to skin altered by diabetes.
Lee
Y S
YS
Department of Pathology, National University of Singapore.
Vijayasingam
S
S
Chan
H L
HL
D000368:Aged; D000686:Amyloidosis / Q000473:pathology*; D001706:Biopsy; D004547:Elastic Tissue / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D005455:Fluorescent Antibody Technique; D006101:Granuloma, Giant Cell / Q000473:pathology*; D006801:Humans; D008854:Microscopy, Electron; D010787:Photosensitivity Disorders / Q000473:pathology*; D012871:Skin Diseases / Q000473:pathology*