Studies on the pathogenicity of classical enteropathogenic Escherichia coli strains isolated from acute diarrhoea among children 0-5 years of age.
The mechanisms of pathogenicity in EPEC strains were studied in tissue culture. Escherichia coli was isolated as the predominant organism in the primary culture of 1293 (70.54%) diarrhoeal cases. 284 (90.44%) cases from the age group of 1-6 months showed Escherichia coli as the predominant organism. Classical Enteropathogenic Escherichia coli (EPEC) were detected in 311 (24.05%) cases. Among EPEC isolates 277 (89.06%) did not produce either LT or ST. 32 (10.28%) produced LT or ST. 2 strains produced verotoxins belong to serotypes 0:86; K:61, 0.26; K:60, serogroups 0.86:K61 0142:K86, 0:128:K67, 0 126: 71, 0125:K 70, 0119: k69 showed localised adherence and serogroups 0111:K58-055:K59 showed both localised and diffused adherence to HeLa cells.
Ananthan
S
S
Subramanian
S
S
Thyagarajan
S P
SP
Jayakumar
V
V
Udayashankar
K
K
Elanchezhiyan
M
M
Sundaram
N S
NS
D001422:Bacterial Adhesion; D002675:Child, Preschool; D003967:Diarrhea / Q000382:microbiology*; D004768:Enterotoxins / Q000096:biosynthesis; D004926:Escherichia coli / Q000302:isolation & purification / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000382:microbiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn
D004768:Enterotoxins