Myasthenia gravis and lymphoblastic lymphoma antiacetylcholine receptor antibody as a tumor marker--a case report.
This report documents an association between lymphoblastic lymphoma and myasthenia gravis. Elevation of acetylcholine receptor antibody titer was an unusual marker for the lymphoblastic lymphoma. Following chemotherapy all symptoms of myasthenia gravis resolved and the acetylcholine receptor antibody titer normalized. The patient remains in complete remission off all therapy 20 months since the diagnosis of myasthenia gravis was made and 12 months after chemotherapy for her lymphoma.
Mortimer
J E
JE
Department of Medicine, University of Washington, Seattle.
Kidd
P
P
D000951:Antigens, Neoplasm / Q000032:analysis; D001323:Autoantibodies / Q000032:analysis*; D005260:Female; D015329:Gene Rearrangement, T-Lymphocyte; D006680:HLA Antigens / Q000032:analysis; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications* / Q000473:pathology / Q000628:therapy; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications* / Q000276:immunology; D011978:Receptors, Nicotinic / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
D000951:Antigens, Neoplasm; D001323:Autoantibodies; D006680:HLA Antigens; D011978:Receptors, Nicotinic