[Partial lipodystrophy and membranoproliferative glomerulonephritis. Apropos of a case].
We have studied a girl seven and a half years old with a renal disease manifested by proteinuria and nephrotic syndrome combined with initial macroscopic hematuria normal blood pressure and persistent depression of the complement C3 levels with the complement activating gamma globulin (C3 Nef) present in serum. The anatomopathological study showed findings of membranoproliferative glomerulonephritis type II with intramembranous deposit (dense deposit disease). An unusual association with partial lipodystrophy was present in this case. A follow-up of five years, and a few considerations about etiopathogenic theories were presented.
Martínez Debora
M J
MJ
Sección de Nefrologia, Hospital Nacional Infantil, Niño Jesús, Madrid.
Vázquez Martul
M
M
Ecija Peiró
J L
JL
González Pérez
J
J
Lirio Rodríguez
J
J
González Mediero
I
I
D002648:Child; D003176:Complement C3 / Q000032:analysis; D003178:Complement C3 Nephritic Factor / Q000032:analysis; D005260:Female; D015432:Glomerulonephritis, Membranoproliferative / Q000150:complications*; D006801:Humans; D008060:Lipodystrophy / Q000150:complications*
D003176:Complement C3; D003178:Complement C3 Nephritic Factor
Lipodistrofia parcial y glomerulonefritis membranoproliferativa. A propósito de un caso.