[Use of beta-methyldigoxin preparations medilazine and bemecor in patients with congestive heart failure].
The two agents beta-methyldigoxin (medixin), a Soviet medilazide, and bemecor (digicor), a foreign analogue (LEK, Yugoslavia) were comparatively evaluated. An equal high (85%) clinical efficacy of the drugs was found in 81 patients with varying stages of heart failure. A positive therapeutic effect was accompanied by lower heart rate, higher diuresis and natri-and kaliuresis, decreased systolic and diastolic pressures in the pulmonary artery. The incidence of adverse reactions and the causes of their occurrence are analyzed.
Razumova
E T
ET
Volov
N A
NA
Savenkov
P M
PM
Grigo'reva
T V
TV
Aleksandrova
E G
EG
Shitikova
L V
LV
Tatarenkova
L V
LV
Sarkisov
A M
AM
D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D004077:Digoxin / Q000031:analogs & derivatives*; D005260:Female; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008520:Medigoxin / Q000493:pharmacokinetics / Q000627:therapeutic use*; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects / Q000502:physiology; D014586:USSR; D015022:Yugoslavia
D004077:Digoxin; D008520:Medigoxin
Primenenie preparatov beta-metildigoksina medilazina i bemekora u bo'lnykh s zastoĭnoĭ serdechnoĭ nedostatochnos'tiu.