Treatment of carbamazepine poisoning by combined hemodialysis/hemoperfusion.
A severe carbamazepine intoxication in a 45-year-old woman was treated with combined hemodialysis/hemoperfusion. The ingested dose was estimated as 4-36 g. Serum carbamazepine levels were determined by fluorescence polarization immunoassay. The detoxication was performed 18 h after admission and resulted in a 50 percent reduction in serum drug levels accompanied by rapid clinical improvement.
Bock
E
E
Freie Universität Berlin, Klinikum Steglitz, Department of Internal Medicine, FRG.
Keller
F
F
Heitz
J
J
Heinemeyer
G
G
D002220:Carbamazepine / Q000097:blood / Q000506:poisoning*; D005260:Female; D005455:Fluorescent Antibody Technique; D006464:Hemoperfusion; D006801:Humans; D008875:Middle Aged; D006435:Renal Dialysis
D002220:Carbamazepine