[Changes in the rat endocrine pancreas under the effect of urbazon].
Hypertrophy and hyperplasia of islet tissue, established by morphometry, were proved in the pancreas of rats, treated chronically for a period of 2 months (with urbason-50 mg/kg of body mass). B-cells were granulated. Structures with myelin-like form of membranes were observed in some of them by electron microscope. Mixed islet B-acinar cells were established as well. These data were possibly a morphological expression of stimulating action of urbason on B-cells of Langerhans islets.
Zafirova
M
M
Zhablenska
R
R
Mikhova
Ts
Ts
Petkov
P
P
Dochev
D
D
D000818:Animals; D006965:Hyperplasia; D006984:Hypertrophy; D007515:Islets of Langerhans / Q000187:drug effects* / Q000473:pathology; D008297:Male; D008775:Methylprednisolone / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
D008775:Methylprednisolone
Promeni v endokrinniia pankreas na plŭkh pod vŭzdeĭstvieto na urbazon.