Evolution of the levels of soluble interleukin-2 receptors during Plasmodium falciparum and P. vivax malaria.
Increased levels of soluble interleukin-2 receptors (IL-2R) in serum were observed in both Plasmodium falciparum- and P. vivax-infected individuals compared with nonparasitemic subjects. Clinical symptoms of P. falciparum malaria were associated with higher levels of soluble IL-2R. Temporal evolution in serum of IL-2R during the course of a malaria attack mimicked the kinetics of soluble IL-2R under experimental conditions.
Deloron
P
P
Institut National de la Santé et de la Recherche Médicale Unité 13, Hôpital Claude Bernard, Paris, France.
Lepers
J P
JP
Coulanges
P
P
D000293:Adolescent; D000328:Adult; D000818:Animals; D002648:Child; D005260:Female; D006801:Humans; D007700:Kinetics; D008137:Longitudinal Studies; D008288:Malaria / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D010963:Plasmodium falciparum; D010966:Plasmodium vivax; D015375:Receptors, Interleukin-2 / Q000096:biosynthesis*
D015375:Receptors, Interleukin-2