Alzheimer's disease: environmental factors and etiologic hypotheses.
A review of published reports on conventional and unconventional viruses, aluminum, neurotoxic metals and trace elements, neurotoxins of biological origin and immune systems, suggest that environmental factors, possibly multiple ones, play a significant role in the etiology of Alzheimer's disease. A complex interaction between genetic predisposition to this illness, natural aging processes, environmental factors over a life-time exposure and pathological alterations of the host immune system is proposed.
Gautrin
D
D
McGill Centre for Studies in Aging, McGill University, Montreal, Quebec, Canada.
Gauthier
S
S
D000544:Alzheimer Disease / Q000139:chemically induced / Q000209:etiology* / Q000382:microbiology; D000818:Animals; D001921:Brain / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008670:Metals / Q000633:toxicity*; D014777:Virus Diseases / Q000150:complications*
D008670:Metals