Inhibition of desipramine 2-hydroxylation by quinidine and quinine in rapid and slow debrisoquine hydroxylators.
Spina
E
E
Institute of Pharmacology, University of Messina, Italy.
Steiner
E
E
Dumont
E
E
Dahlqvist
R
R
D003647:Debrisoquin / Q000378:metabolism*; D003864:Depression, Chemical; D003891:Desipramine / Q000378:metabolism*; D006801:Humans; D006900:Hydroxylation; D007546:Isoquinolines / Q000378:metabolism*; D010641:Phenotype; D011802:Quinidine / Q000494:pharmacology*; D011803:Quinine / Q000494:pharmacology*
D007546:Isoquinolines; D011803:Quinine; D011802:Quinidine; D003891:Desipramine; D003647:Debrisoquin