[The importance of the radioimmunological determination of tumor markers in the diagnosis of malignant lymphomas].
The investigation was conducted to study the role of the determination of tumor markers (CEA, beta 2-microglobulin, IgE and ferritin) in patients with malignant lymphomas. Altogether 66 patients with Hodgkin's disease, 60 with non-Hodgkin's lymphomas and 15 with clinico-hematological remission over one year were investigated, using commercial kits of reagents. An increase in the level of beta 2 was shown to depend on the spreading of a lymphoproliferative process. An elevated level of IgE was noted in Hodgkin's disease whereas a significant rise was unnoticed in non-Hodgkin's lymphomas. An increase in the level of serum ferritin was noted in an advanced and aggressive lymphoproliferative process. The CEA test in malignant lymphomas is not informative.
Purizhanskiĭ
I I
II
Pavlichuk
S N
SN
Toritsina
L K
LK
D000375:Aging / Q000097:blood; D014408:Biomarkers, Tumor / Q000097:blood*; D002272:Carcinoembryonic Antigen / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D005293:Ferritins / Q000097:blood; D006689:Hodgkin Disease / Q000175:diagnosis; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D008206:Lymphatic Diseases / Q000175:diagnosis; D008223:Lymphoma / Q000175:diagnosis*; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis; D008297:Male; D011863:Radioimmunoassay; D012727:Sex Characteristics; D001613:beta 2-Microglobulin / Q000032:analysis
D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D001613:beta 2-Microglobulin; D007073:Immunoglobulin E; D005293:Ferritins
Znachenie radioimmunologicheskogo opredeleniia opukholevykh markerov v diagnostike zlokachestvennykh limfom.