title: The validity of screening for small-for-gestational-age and low-weight-for-length infants by Doppler ultrasound.
abstract: A prospective blind study assessed the efficacy of Doppler examination of the umbilical arteries (pulsatility index) as a screening procedure for predicting small-for-gestational-age and low-weight-for-length (low ponderal index) infants. Birthweight below the 2.3rd and 10th centile and ponderal index below the 3rd and 10th centile were chosen as 'cut-off' levels. Of pregnant women from our university hospital population, 400 were examined at 28 and 34 weeks gestation. The sensitivity of the test was low, ranging from 16.9 to 41.7% for the different indices. The predictive value of a negative screening test also was unsatisfactory, ranging from 79.6% to 97.9%. It is concluded that a single umbilical artery Doppler examination at 28 or 34 weeks does not satisfy the need in obstetrics for a simple and accurate technique to screen for small-for-gestational-age and low-weight-for-length infants in an unselected obstetric population.
authors.affiliation: Dept of Obstetrics, University Hospital, Utrecht, The Netherlands.
authors.forename: E A
authors.initials: EA
authors.lastname: Sijmons
authors.forename: P J
authors.initials: PJ
authors.lastname: Reuwer
authors.forename: E
authors.initials: E
authors.lastname: van Beek
authors.forename: H W
authors.initials: HW
authors.lastname: Bruinse
mesh_terms: D005314:Embryonic and Fetal Development; D005260:Female; D006801:Humans; D007230:Infant, Low Birth Weight / Q000502:physiology*; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age / Q000502:physiology*; D011237:Predictive Value of Tests; D011247:Pregnancy; D011296:Prenatal Diagnosis; D011446:Prospective Studies; D012039:Regional Blood Flow; D014463:Ultrasonography; D014469:Umbilical Arteries / Q000503:physiopathology