Major ocular glands (harderian gland and lacrimal gland) of the musk shrew (Suncus murinus) with a review on the comparative anatomy and histology of the mammalian lacrimal glands.
The Harderian gland of the musk shrew Suncus murinus is elongated anteroposteriorly from in front of the eye to behind the ear. The gland is divided into two portions: an anterior portion (A portion) and a posterior portion (P portion). The single secretory duct of the gland emerges from the anterior end of the P portion, receives several secretory ducts of the A portion during the course along it, runs around the ventral aspect of the eyeball, and finally opens into the anterior corner of conjunctival sacs. The two portions of the gland show a fundamentally similar histological structure, having a poorly developed intraglandular duct system and wide tubular alveoli. The quantity of lipid vacuoles and stromal connective tissue in the A portion is greater than in the P portion. The lipid vacuoles in both portions are surrounded by unit membranes, but their contents appear different. The lacrimal gland of the musk shrew is located along the ventral side of the P portion of the Harderian gland. The lacrimal duct emerges from its anterior end, runs around the ventral and anterior aspects of the ear, crosses the A portion of the Harderian gland, and finally opens at the posterior corner of conjunctival sacs. The lobules of the lacrimal gland comprise a branched duct system and terminal acini with two types of secretory cells: 1) acidic cells positive both for the periodic acid-Schiff reaction (PAS) and for Alcian blue (AB) and 2) neutral cells positive for PAS and negative for AB. Both cell types tend to make separate acini, but when present in the same acinus, the acidic cells occupy relatively peripheral positions in the acinus. Both cell types lack intercellular canaliculi. On the basis of the present study as well as previous descriptions in the literature, the author suggests that the mammalian lacrimal glands can be divided into two sets: 1) a Glandula lacrimalis superior with multiple secretory ducts associated with the upper eyelid and 2) a Glandula lacrimalis inferior with a single secretory duct opening into the lateral corner of the conjunctival sacs. These glands have a fundamentally similar histological structure; but in the rabbit, which possesses both sets of lacrimal glands, they are different. On the other hand, the secretory cells of lacrimal glands generally have no intercellular secretory canaliculi, which are characteristically present between the serous secretory cells of the salivary glands.
Sakai
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Department of Anatomy, Faculty of Medicine, University of Tokyo, Japan.
D000717:Anatomy, Comparative; D000818:Animals; D006243:Harderian Gland / Q000033:anatomy & histology* / Q000648:ultrastructure; D007765:Lacrimal Apparatus / Q000033:anatomy & histology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D012788:Shrews / Q000033:anatomy & histology*