title: Effect of prior cardiac surgery on survival after heart transplantation.
abstract: We conducted a retrospective analysis of 182 adult orthotopic heart transplant patients who underwent operations at our institution between July 1982 and October 1987 to determine whether prior cardiac operation affects survival. Group I included the 72 patients (39.6%) who had undergone a previous cardiac operation or operations and group II, the 110 (60.4%) who had not. The mean age of the patients in group I was 52.1 +/- 8.1 years and in group II, 46.1 +/- 10.2 years (p less than 0.01). The incidence of ischemic heart disease was 86.1% in group I and 29.1% in group II (p less than 0.01). All patients received cyclosporine-based immunosuppression. More patients in group I than in group II required reoperation for bleeding after transplantation: 18 (25.0%) versus 9 (8.2%) (p less than 0.01). The actuarial 1-year and 3-year survival rates were 77.6% and 66.5%, respectively, for group I and 77.1% and 66.3%, respectively, for group II. Because both groups had similar survival rates, we believe that prior cardiac operation in heart transplant recipients does not compromise long-term survival.
authors.affiliation: Section of Transplantation, Texas Heart Institute, Houston 77225.
authors.forename: D E
authors.initials: DE
authors.lastname: Lammermeier
authors.forename: T
authors.initials: T
authors.lastname: Nakatani
authors.forename: M S
authors.initials: MS
authors.lastname: Sweeney
authors.forename: C T
authors.initials: CT
authors.lastname: Van Buren
authors.forename: M P
authors.initials: MP
authors.lastname: Macris
authors.forename: J M
authors.initials: JM
authors.lastname: Duncan
authors.forename: O H
authors.initials: OH
authors.lastname: Frazier
mesh_terms: D000328:Adult; D006348:Cardiac Surgical Procedures / Q000401:mortality*; D005260:Female; D005500:Follow-Up Studies; D016027:Heart Transplantation; D006470:Hemorrhage / Q000209:etiology / Q000601:surgery; D006801:Humans; D007239:Infections / Q000209:etiology / Q000401:mortality; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality* / Q000601:surgery; D012086:Reoperation; D012189:Retrospective Studies