Recombinant DNA technology and clinical dentistry.
The introduction of recombinant DNA technology in the late 1970s led to rapid advancements in our knowledge of genes and genomic structure in the 1980s. Such technology, applied to the human genome, provides new information concerning the nature and possible treatment of inherited disorders throughout the human lifespan. Methods to clone structural genes of interest to clinical dentistry now provide strategies to produce genetically engineered biomaterials for prosthetic dentistry. This methodology is also being used to clone microbial DNAs for periodontal disease diagnosis, therapy, and prognostic applications.
Slavkin
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D004274:DNA, Recombinant; D003729:Dental Care; D005818:Genetic Engineering; D006801:Humans
D004274:DNA, Recombinant