title: The changing spectrum of splenic abscess.
abstract: Thirteen cases of splenic abscess were reviewed retrospectively from pathologic and medical records from 1978 through 1986. Splenic abscess is uncommon, but the diagnosis has been made more frequently in recent years due to the increasing number of living immunosuppressed patients and to the use of more sophisticated radiologic diagnostic techniques. Five patients had a solitary abscess (SA) and eight had multiple abscesses (MA). Seventy-five percent of the patients with MA were immunosuppressed, most had no symptoms from the splenic abscess, and none died. Only one patient (with SA) died, a mortality of 10% overall. Previously the mortality has been 40 to 70%. The decreased mortality may in part be attributable to the more rapid diagnosis (3.8 days for SA, 1.8 days for MA) of the splenic abscess, prompting early treatment. Improved radiologic studies reduce the time to diagnosis and thereby improve the prognosis. Computed tomography (CT) was diagnostic for splenic abscess in 4 of 7 patients and suggestive of abscess in the other 3. Computed tomography was the diagnostic modality of choice in suspected splenic abscess, as it provided more information than the other radiologic studies used.
authors.affiliation: Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, Maryland.
authors.forename: P L
authors.initials: PL
authors.lastname: Caslowitz
authors.forename: J D
authors.initials: JD
authors.lastname: Labs
authors.forename: E K
authors.initials: EK
authors.lastname: Fishman
authors.forename: S S
authors.initials: SS
authors.lastname: Siegelman
mesh_terms: D000038:Abscess / Q000175:diagnosis* / Q000000981:diagnostic imaging; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D013156:Splenectomy; D013158:Splenic Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography