Pulmonary surfactant: physiology, pharmacology and clinical uses.
The endogenous surfactant system in the lungs is complex. The synthetic, recycling and metabolic pathways are clear but the controlling mechanisms are not fully understood. Surfactant-specific proteins are important and their isolation and manufacture opens up new prospects for production of a synthetic surfactant with all the properties of natural human surfactant for therapy and prophylaxis of neonatal respiratory distress syndrome.
Morton
N S
NS
Royal Hospital for Sick Children, Glasgow.
D006801:Humans; D007231:Infant, Newborn; D011663:Pulmonary Surfactants / Q000494:pharmacology* / Q000627:therapeutic use; D012127:Respiratory Distress Syndrome, Newborn / Q000188:drug therapy*
D011663:Pulmonary Surfactants