Radiomodifying influence of camphor on sister-chromatid exchange induction in mouse bone marrow.
The frequency of sister-chromatid exchanges (SCE) in mouse bone marrow exposed to gamma-irradiation was used to assess the radiomodifying effect of camphor. Hoechst 33258 plus Giemsa was used for SCE analysis. The radiation-induced SCE frequency was significantly low after a single dose of camphor (0.5 microM/g b.w.) administered 30, 45 or 60 min before irradiation; the effect was enhanced with increasing time intervals.
Goel
H C
HC
Institute of Nuclear Medicine and Allied Sciences, Delhi, India.
Singh
S
S
Singh
S P
SP
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects* / Q000528:radiation effects; D002164:Camphor / Q000633:toxicity*; D051379:Mice; D008805:Mice, Inbred A; D011838:Radiation-Sensitizing Agents / Q000633:toxicity*; D012854:Sister Chromatid Exchange / Q000187:drug effects* / Q000528:radiation effects; D014916:Whole-Body Irradiation
D011838:Radiation-Sensitizing Agents; D002164:Camphor