The role of the endothelium in myocardial lipoprotein dynamics.
This overview is presented, in the main, to summarize the following areas of myocardial lipoprotein metabolism: 1. The nature and extent of the cardiac endothelium. 2. The interactions between the endothelium and chylomicrons, very low, low and high density lipoproteins in the presence and absence of lipoprotein lipase. 3. The importance of the endothelial lipoprotein lipase and the mechanisms involved in the enzymes' sequestration at that site. 4. The physiological role of lipoprotein lipase in the provision of oxidizable fuel for the heart.
Cryer
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Department of Biochemistry, University of Wales, Cardiff, United Kingdom.
D000818:Animals; D001692:Biological Transport; D002914:Chylomicrons / Q000378:metabolism; D004730:Endothelium, Vascular / Q000502:physiology*; D006801:Humans; D008071:Lipoprotein Lipase / Q000502:physiology; D008074:Lipoproteins / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism*
D002914:Chylomicrons; D008074:Lipoproteins; D008071:Lipoprotein Lipase