Impaired bone marrow in AIDS.
Fifty bone marrows from patients with AIDS were studied to identify the abnormalities related to marrow failure. Prominent reticulin fibrosis and increased atypical megakaryocytes were the major changes associated with the aberrant hematopoietic microenvironment.
Mehta
K U
KU
Gascon
P
P
Tannir
N
N
Lombardo
J
J
Robboy
S J
SJ
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000473:pathology; D000328:Adult; D001855:Bone Marrow Diseases / Q000209:etiology* / Q000473:pathology; D001856:Bone Marrow Examination; D005260:Female; D006413:Hematopoietic System / Q000473:pathology; D006801:Humans; D008297:Male; D008533:Megakaryocytes / Q000473:pathology; D008875:Middle Aged; D009894:Opportunistic Infections / Q000209:etiology; D012189:Retrospective Studies