A mutagenic new iridoid in the water extract of catalpae fructus.
A mutagenic principle in the water extract from Catalpae Fructus (originated from Catalpa ovata G. DON) (Bignoniaceae) was isolated and characterized as a new iridoid named catalpin. The iridoid exhibited mutagenic activity towards Salmonella typhimurium strain TA100 in the presence and absence of rat liver homogenate (S9) mix in Ames' test.
Nozaka
T
T
Watanabe
F
F
Ishino
M
M
Morimoto
I
I
Kondoh
H
H
Koyama
K
K
Natori
S
S
D000818:Animals; D066298:In Vitro Techniques; D008297:Male; D009153:Mutagens; D010936:Plant Extracts / Q000032:analysis*; D010946:Plants, Medicinal / Q000032:analysis*; D011714:Pyrans / Q000302:isolation & purification / Q000633:toxicity*; D051381:Rats; D011919:Rats, Inbred Strains; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics
D009153:Mutagens; D010936:Plant Extracts; D011714:Pyrans; C062858:catalpin