title: Epidural anaesthesia and blood flow velocity in mother and fetus.
abstract: Doppler ultrasound has recently been used to assess changes in blood velocity in the uterine and umbilical arteries. Alterations in the ratio of systolic to diastolic velocity (S/D ratio) are believed to reflect changes in placental vascular resistance. We have used this technique to assess potential beneficial or detrimental effects of epidural anaesthesia on blood flow to the placenta. Continuous wave Doppler ultrasound was used to measure the S/D ratio in the uterine and umbilical arteries of 12 patients undergoing epidural anaesthesia prior to elective caesarean section. Anaesthesia was achieved using lidocaine and epinephrine. The S/D ratio in both the uterine and umbilical arteries remained unaltered either by the fluid preload or by the epidural anaesthesia. It is concluded that epidural anaesthesia using this technique has neither a beneficial nor detrimental effect on uterine or umbilical blood velocity in the uncomplicated pregnancy.
authors.affiliation: Department of Obstetrical Perinatology, Mount Sinai Hospital, University of Toronto Perinatal Complex, Ontario.
authors.forename: R J
authors.initials: RJ
authors.lastname: Morrow
authors.forename: S H
authors.initials: SH
authors.lastname: Rolbin
authors.forename: J W
authors.initials: JW
authors.lastname: Ritchie
authors.forename: S
authors.initials: S
authors.lastname: Haley
mesh_terms: D000767:Anesthesia, Epidural; D000773:Anesthesia, Obstetrical; D001158:Arteries; D001783:Blood Flow Velocity / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D005260:Female; D005333:Fetus; D006801:Humans; D008012:Lidocaine / Q000494:pharmacology; D009200:Myocardial Contraction; D010920:Placenta / Q000098:blood supply*; D011247:Pregnancy; D011897:Random Allocation; D014463:Ultrasonography; D014469:Umbilical Arteries / Q000502:physiology*; D014599:Uterus / Q000098:blood supply*
chemical_list: D008012:Lidocaine