[The protective action of thymopentin on stress damage to the stomach].
The influence of peptide thymopentin on ulcer effects of the stomach mucous membrane in rats and the state of its processes in acute and chronic stress as well as their combination influence were investigated. The intercommunication of frequency of the formation of ulcer and the activity of superoxide dismutase in stomach fibers was established. Thymopentin displayed a marked antiulcerogenic effect in all kinds of stress.
Deviatkina
T A
TA
Tarasenko
L M
LM
Klusha
V E
VE
Tsebrzhinskiĭ
O I
OI
Mutsenietse
R K
RK
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000818:Animals; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D004353:Drug Evaluation, Preclinical; D005753:Gastric Mucosa / Q000187:drug effects / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D010446:Peptide Fragments / Q000627:therapeutic use*; D051381:Rats; D011919:Rats, Inbred Strains; D012149:Restraint, Physical; D013276:Stomach Ulcer / Q000209:etiology / Q000517:prevention & control*; D013315:Stress, Psychological / Q000150:complications*; D013482:Superoxide Dismutase / Q000378:metabolism; D016305:Thymopentin; D013946:Thymopoietins / Q000627:therapeutic use*; D013951:Thymus Hormones / Q000627:therapeutic use*; D013997:Time Factors
D000276:Adjuvants, Immunologic; D000897:Anti-Ulcer Agents; D010446:Peptide Fragments; D013946:Thymopoietins; D013951:Thymus Hormones; D013482:Superoxide Dismutase; D016305:Thymopentin
Zashchitnoe deĭstvie timopentina na stressornoe povrezhdenie zheludka.