title: Continuous versus intermittent epidural analgesia. A randomised trial to observe obstetric outcome.
abstract: A randomised study of 381 women was carried out to compare the obstetric outcome after epidural analgesia maintained by an intermittent top-up regimen or with a continuous infusion. The two groups were well matched with respect to age, parity, mode of onset of labour and indication for epidural. Maintenance of epidural analgesia by continuous infusion resulted in a significantly decreased need for top-up doses. A reduction in the incidence of hypotension, cardiotocographic evidence of intrapartum fetal hypoxia and Caesarean section was associated with this. It is concluded that the maintenance of epidural analgesia by continuous infusion is a safe and reliable method and may be more advantageous and less labour intensive than the traditional intermittent regimen.
authors.affiliation: University of Southampton, Department of Human Reproduction and Obstetrics.
authors.forename: R F
authors.initials: RF
authors.lastname: Lamont
authors.forename: D
authors.initials: D
authors.lastname: Pinney
authors.forename: P
authors.initials: P
authors.lastname: Rodgers
authors.forename: T N
authors.initials: TN
authors.lastname: Bryant
mesh_terms: D015360:Analgesia, Epidural / Q000379:methods*; D000773:Anesthesia, Obstetrical / Q000379:methods*; D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic