Betel cytotoxicity.
An attempt to summarise the phytochemical composition of the betel quid, formation of N-nitrosation products during chewing, results of carcinogenicity and mutagenicity studies and the relationship between betel chewing and submucous fibrosis have been made from presently available literature. The present review provides a better understanding of the capacity of the quid ingredients in inducing preneoplastic changes for evaluation of the risk involved with its chewing.
Sen
S
S
Department of Botany, University of Calcutta, India.
Talukder
G
G
Sharma
A
A
D000818:Animals; D001114:Areca; D002273:Carcinogens; D003603:Cytotoxins; D006801:Humans; D009062:Mouth Neoplasms / Q000209:etiology; D009153:Mutagens; D009602:Nitrosamines / Q000009:adverse effects; D010936:Plant Extracts / Q000009:adverse effects; D010946:Plants, Medicinal
D002273:Carcinogens; D003603:Cytotoxins; D009153:Mutagens; D009602:Nitrosamines; D010936:Plant Extracts