title: Infectious complications of marrow transplant: risk factors for infection.
abstract: Severe infection is a predictable accompaniment of marrow transplant. Advances in therapy for bacterial and some viral infections have reduced the impact of these infections. In contrast, infection due to fungi continue to play a major and even increasing role. The relationship between GVHD and infection is poorly understood, although it is clear that GVHD (and perhaps its treatment) has a major influence on the acquisition and outcome of infection. Advances in the prevention and treatment of GVHD will undoubtedly have parallel benefits in the prevention of infection after marrow transplant.
authors.affiliation: Program in Infectious Diseases, Fred Hutchinson Cancer Research Center, Seattle, Washington.
authors.forename: J D
authors.initials: JD
authors.lastname: Meyers
authors.forename: R A
authors.initials: RA
authors.lastname: Bowden
authors.forename: G W
authors.initials: GW
authors.lastname: Counts
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000209:etiology*; D016026:Bone Marrow Transplantation; D006086:Graft vs Host Disease / Q000209:etiology*; D006801:Humans; D009181:Mycoses / Q000209:etiology*; D012307:Risk Factors; D014777:Virus Diseases / Q000209:etiology*
chemical_list: D000890:Anti-Infective Agents