[Iopromide 300 and 370. Meta-analysis of a randomized prospective clinical trial conducted in France in 1987. Overall results of tolerability and efficacy].
The results of a multicentre prospective randomized study are presented as a meta-analysis, comparing a new non-ionic iodinated contrast medium, iopromide, with the ionic low osmolar medium, ioxaglate. It shows the better safety of iopromide in 322 patients, with a statistically significant difference for the following items: nausea (p less than 0.002), swallowing movements (p less than 0.001), urticaria (p less than 0.05) and all clinical parameters tested, excluding heat sensation, which was too subjective for quantitification (p less than 0.0001).
Broussel
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D003287:Contrast Media; D006801:Humans; D007472:Iohexol / Q000009:adverse effects* / Q000031:analogs & derivatives; D007485:Ioxaglic Acid / Q000009:adverse effects; D008536:Meglumine / Q000009:adverse effects; D015201:Meta-Analysis as Topic; D015337:Multicenter Studies as Topic; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic
D003287:Contrast Media; D007472:Iohexol; D008536:Meglumine; C038192:iopromide; D007485:Ioxaglic Acid
Iopromide 300 et 370. Méta-analyse d'un essai clinique randomisé prospectif mené en France en 1987. Résultats globaux de tolérance et d'efficacité.