[Positron emitters for the study of tumor metabolism].
Positron emission tomography with metabolically active substances is a noninvasive imaging modality to determine tumor metabolism. Quantification of tumor metabolism provides valuable information, e.g., for the differential diagnosis of malignancies. Radiolabeled therapeutic substances can be traced with PET. Measurement of fluorouracil metabolite concentrations provides data about the accumulation pattern of the cytostatic agent and allows assessment of the therapeutic outcome.
Strauss
L G
LG
Institut für Radiologie und Pathophysiologie, Deutsches Krebsforschungszentrum, Heidelberg.
D003847:Deoxyglucose / Q000031:analogs & derivatives; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D005472:Fluorouracil / Q000493:pharmacokinetics / Q000627:therapeutic use; D006801:Humans; D009369:Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000378:metabolism*; D014055:Tomography, Emission-Computed
D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D003847:Deoxyglucose; D005472:Fluorouracil
Positronenstrahler für die Erforschung des Tumorstoffwechsels.