title: De novo lipogenesis and lipolysis activities in normal (Dw) and dwarf (dw) White Leghorn laying hens.
abstract: 1. In vitro activities of glucose oxidation, de novo lipogenesis and lipolysis were compared in normal (Dw) and dwarf (dw) laying hens. 2. Dwarfism reduced the hepatic glucose oxidation while de novo lipogenesis was not altered. As liver weight was depressed, total liver lipogenesis capacity was probably reduced by dwarfism. 3. As compared to normal hens, de novo lipogenesis and basal or stimulated lipolysis were lower in dwarf adipose tissue while its lipid content was enhanced in dwarfs. 4. Results suggest that in laying hens dwarfism reduces the adipose tissue lipid mobilization but probably also the liver de novo lipogenesis.
authors.affiliation: Station de Recherches de Nutrition, INRA-CRJ, Jouy-en-Josas, France.
authors.forename: C
authors.initials: C
authors.lastname: Burghelle-Mayeur
authors.forename: M
authors.initials: M
authors.lastname: Tixier-Boichard
authors.forename: P
authors.initials: P
authors.lastname: Merat
authors.forename: Y
authors.initials: Y
authors.lastname: Demarne
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D000821:Animal Feed; D000818:Animals; D002395:Catecholamines / Q000494:pharmacology; D002645:Chickens / Q000235:genetics*; D004041:Dietary Fats / Q000008:administration & dosage; D004392:Dwarfism / Q000378:metabolism; D005260:Female; D005934:Glucagon / Q000494:pharmacology; D005947:Glucose / Q000378:metabolism; D007328:Insulin / Q000494:pharmacology; D008055:Lipids / Q000096:biosynthesis*; D008066:Lipolysis; D008099:Liver / Q000378:metabolism; D010084:Oxidation-Reduction
chemical_list: D002395:Catecholamines; D004041:Dietary Fats; D007328:Insulin; D008055:Lipids; D005934:Glucagon; D005947:Glucose