title: [Magnetic resonance tomography and multiple sclerosis].
abstract: Magnetic resonance tomography (MRI) is the imaging technique of first choice in diseases of the white matter of the central nervous system (CNS) including multiple sclerosis (MS). The signal changes observed are not specific, however, and have to be evaluated critically in the clinical context. The most difficult problems of differential diagnosis arise from other inflammatory diseases of the CNS like cerebral lupus, neurosarcoidosis, Behçet's syndrome and other vasculitides. MRI allows for the first time in vivo studies of the blood-brain barrier which is so important in MS pathogenesis. A great potential for MRI is in monitoring putative therapies in MS.
authors.forename: J
authors.initials: J
authors.lastname: Kesselring
mesh_terms: D000293:Adolescent; D000328:Adult; D002493:Central Nervous System Diseases / Q000175:diagnosis*; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000175:diagnosis*; D011379:Prognosis; D012680:Sensitivity and Specificity
vernacular_title: Magnetresonanztomographie (MRI) und multiple Sklerose (MS).