title: [Ginkgo biloba extract and folic acid in the therapy of changes caused by autonomic neuropathy].
abstract: 10 patients suffering from neuropathies caused by various diseases and with an autonomic disregulation of skin were treated intravenously with a new combination of 87.5 mg Ginkgo-biloba-extract standardized to 21.0 mg Flavonglycosids and 3 mg folic acid during 14 days. The autonomic nerve-function was measured immediately before onset and after the end of therapy with the hyperthermal laser-Doppler-Flowmetry. Additionally pain, superficial and deep sensibility were described. After the end of treatment the autonomic nerve-function was improved in a significant manner (p less than 0.01). An improvement of the described parameters for pain and for perception could be observed too. Therefore this new combination seems to be suited for treatment of polyneuropathies.
authors.affiliation: Krankenhaus der Barmherzigen Brüder, Graz-Eggenberg.
authors.forename: P
authors.initials: P
authors.lastname: Költringer
authors.forename: W
authors.initials: W
authors.lastname: Langsteger
authors.forename: P
authors.initials: P
authors.lastname: Lind
authors.forename: P
authors.initials: P
authors.lastname: Wakonig
authors.forename: G
authors.initials: G
authors.lastname: Klima
authors.forename: O
authors.initials: O
authors.lastname: Eber
mesh_terms: D000328:Adult; D000368:Aged; D001342:Autonomic Nervous System Diseases / Q000188:drug therapy*; D001783:Blood Flow Velocity / Q000187:drug effects; D003929:Diabetic Neuropathies / Q000188:drug therapy*; D004224:Diterpenes; D005260:Female; D005492:Folic Acid / Q000008:administration & dosage*; D046934:Ginkgolides; D006801:Humans; D007262:Infusions, Intravenous; D007783:Lactones / Q000008:administration & dosage*; D007834:Lasers; D008297:Male; D008833:Microcirculation / Q000187:drug effects; D008875:Middle Aged; D010936:Plant Extracts / Q000627:therapeutic use*; D012867:Skin / Q000098:blood supply*
chemical_list: D004224:Diterpenes; D046934:Ginkgolides; D007783:Lactones; D010936:Plant Extracts; D005492:Folic Acid; C045856:ginkgolide B
vernacular_title: Ginkgo-biloba-Extrakt und Folsäure in der Therapie von autonomen neuropathischen Veränderungen.