[Mutagenicity and harmful effects of anthraquinone dyes on DNA].
By means of the Eims test it was shown that 4 of 8 anthraquinone dyes had low mutagenicity and that of 3 dyes was doubtful. Damaging effect on DNA (alkaline elution test) was not detected. The test of sister chromatids' metabolism in mice bone marrow revealed no mutagenicity in any substance. During the Eims tests alizarin acidic blue had no activity and there were also no dominant lethal mutations but it was active during micronuclear test.
Vasil'eva
L A
LA
Pylev
L N
LN
Sikora
M
M
Guretska
D
D
Gurska
E
E
D000818:Animals; D000880:Anthraquinones / Q000633:toxicity*; D004396:Coloring Agents / Q000633:toxicity*; D004269:DNA, Bacterial / Q000187:drug effects*; D004353:Drug Evaluation, Preclinical; D066298:In Vitro Techniques; D051379:Mice; D009152:Mutagenicity Tests; D009154:Mutation; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics*; D012854:Sister Chromatid Exchange / Q000187:drug effects
D000880:Anthraquinones; D004396:Coloring Agents; D004269:DNA, Bacterial
Mutagennost' i povrezhdaiushchee deĭstvie na DNK antrakhinonovykh krasiteleĭ.