Small lymphocytic pulmonary lymphoma. Diagnosis by transthoracic fine needle aspiration.
A 77-year-old woman was found to have multiple densities on chest roentgenogram. Exfoliative cytology, bronchoscopy with brushings and washings, and transbronchial biopsy revealed a monomorphic population of small lymphocytes suggestive of lymphoma. Transthoracic fine-needle aspiration was performed to provide additional material for immunologic marker study. Immunocytochemistry revealed a monoclonal population of B-cells, which confirmed a diagnosis of small lymphocytic lymphoma. Chemotherapy resulted in significant clinical and roentgenographic improvement.
Sprague
R I
RI
Department of Pathology, Medical College of Virginia, Virginia Commonwealth University, Richmond.
deBlois
G G
GG
D000368:Aged; D001402:B-Lymphocytes / Q000473:pathology; D001707:Biopsy, Needle; D002699:Chlorambucil / Q000627:therapeutic use; D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy / Q000473:pathology*; D008168:Lung / Q000473:pathology*; D008175:Lung Neoplasms / Q000188:drug therapy / Q000473:pathology*
D002699:Chlorambucil