title: [Effectiveness of the Russian drug prazosin in patients with arterial hypertension (Working Group for the Cooperative Study of New Drugs in the Prevention of Arterial Hypertension (CSDPAH)].
abstract: The results of a comparative study of the action of a new Soviet agent prazosin in arterial hypertension patients have shown that it does not differ in its pharmacokinetic characteristics from its Finnish analogue and is an effective hypotensive agent. A short course of prazosin treatment caused hypotensive effect in 85.8 per cent of the patients. The clinical effectiveness and tolerance of both agents is the same.
mesh_terms: D000328:Adult; D002986:Clinical Trials as Topic; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D011224:Prazosin / Q000627:therapeutic use*; D014586:USSR
chemical_list: D011224:Prazosin
vernacular_title: Effektivnost' otechestvennogo preparata prazozina u bol'nykh s arterial'noĭ gipertenzieĭ (rabochaia gruppa kooperativnogo issledovaniia po izucheniiu i profilaktike arterial'noĭ gipertenzii (KIPPAG).