title: [Determination of the composition of the concretions in patients with nephrolithiasis by metabolic indices].
abstract: The authors considered an important problem of in vivo verification of urolith composition as specifying the choice of drug treatment and prevention of urolithiasis. 84 nephrolithiasis patients were allocated to 4 groups according to their concrement compositions (after spontaneous or surgical removal): 23 patients with urate calculus, 19 with oxalate, 20 with phosphate and 22 with oxalate-phosphate concrements. Polarizing microscopy, x-ray structural analysis and infrared spectrophotometry were employed for verification of calculi composition. Biochemical assay was used for the assessment of serum and circadian excretion of calcium, phosphates, sodium, potassium, uric acid, oxalates and uroacidimetric values. The findings were subjected to discriminant computed analysis which resulted in 6 linear computable functions defining 4 selective groups with regard to biochemical blood and urine data. The aforementioned functions were used in diagnostic routine for the in vivo assessment of calculous composition in 26 controls. In 61.5 per cent of the patients the diagnosis was confirmed, in 34.6 per cent it was verified, and only in 3.9 per cent the diagnosis turned to be erroneous.
authors.forename: M V
authors.initials: MV
authors.lastname: Chudnovskaia
authors.forename: N N
authors.initials: NN
authors.lastname: Popovkin
authors.forename: G
authors.initials: G
authors.lastname: Schubert
authors.forename: N V
authors.initials: NV
authors.lastname: Grishkova
authors.forename: G
authors.initials: G
authors.lastname: Brien
mesh_terms: D003936:Diagnosis, Computer-Assisted; D005260:Female; D006801:Humans; D007669:Kidney Calculi / Q000032:analysis* / Q000175:diagnosis / Q000378:metabolism; D008297:Male; D008859:Microscopy, Polarization; D008875:Middle Aged; D010070:Oxalates / Q000032:analysis / Q000378:metabolism; D010710:Phosphates / Q000032:analysis / Q000378:metabolism; D013055:Spectrophotometry, Infrared; D014527:Uric Acid / Q000032:analysis / Q000378:metabolism; D014961:X-Ray Diffraction
chemical_list: D010070:Oxalates; D010710:Phosphates; D014527:Uric Acid
vernacular_title: Opredelenie sostava konkrementov u bol'nykh nefrolitiazom po metabolicheskim pokazateliam.