title: [Comparative effectiveness of finoptin and phosphobion in treating attacks of supraventricular tachycardia].
abstract: Forty-seven cases of supraventricular reciprocal paroxysmal tachycardia in patients with a complementary atrioventricular junction, with retrograde flow only, were studied. An attack of tachycardia was induced by frequent transesophageal stimulation of the left atrium. Records from the esophageal lead were taken in addition to external ECG leads. An attack of supraventricular paroxysmal tachycardia could be controlled in 22 (88.0%) cases following a 10 mg intravenous dose of finoptin, and in 15 (68.2%) cases following a 10 mg phosphobion dose. The electrophysiological mechanism of the control of tachycardia by finoptin was the antegrade block of impulse conduction through the atrioventricular node in 21 (95.5%) patients, and retrograde block of the complementary atrioventricular pathway in 1 (4.5%) patient. Under the effect of phosphobion, antegrade atrioventricular block was seen in all cases. The time needed to arrest an attack by the drugs examined ranged from a few seconds to 5 minutes. The use of phosphobion was associated with more marked changes of atrioventricular conductivity and more pronounced subjective sensations.
authors.forename: A I
authors.initials: AI
authors.lastname: Lukoshiavichiute
authors.forename: D A
authors.initials: DA
authors.lastname: Gedrimene
mesh_terms: D000255:Adenosine Triphosphate / Q000627:therapeutic use*; D000293:Adolescent; D000328:Adult; D000368:Aged; D001283:Atrioventricular Node / Q000187:drug effects / Q000503:physiopathology; D002986:Clinical Trials as Topic; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013614:Tachycardia, Paroxysmal / Q000188:drug therapy* / Q000503:physiopathology; D013617:Tachycardia, Supraventricular / Q000188:drug therapy* / Q000503:physiopathology; D014700:Verapamil / Q000627:therapeutic use*
chemical_list: D000255:Adenosine Triphosphate; D014700:Verapamil
vernacular_title: Sravnitel'naia éffektivnost' finoptina i fosfobiona pri kupirovanii pristupov nadzheludochkovoĭ takhikardii.