Effect of dry, soft moist, and canned dog foods on postprandial blood glucose and insulin concentrations in healthy dogs.
The effect of dry, soft moist, and canned dog foods on immediate postprandial plasma glucose and insulin concentrations was evaluated in clinically normal dogs. Dogs were fed either dry (10 dogs; group I), soft moist (10 dogs; group II), or canned (8 dogs; group III) dog food for 5 consecutive days. On the fifth day, plasma glucose and insulin concentrations were determined in each dog prior to, during, and at 5, 10, 15, 30, 45, 60, 90, 120, 180, and 240 minutes after ingestion of the food. The alterations in plasma glucose concentrations were not significantly different from prefeeding values until 240 and 180 minutes after feeding for groups I and III, respectively. In contrast, the increments in plasma glucose were significantly (P less than 0.01) increased from basal concentrations at 30 and 45 minutes after feeding in group-II dogs. The maximal mean postprandial plasma glucose concentration was significantly (P less than 0.0001) less for group III, compared with concentrations for groups I and II, but there was no significant difference between concentrations for groups I and II. Although a biphasic insulin secretory response was found in all 3 groups of dogs, the patterns of phase-2 insulin secretion and the total amount of insulin secreted during the study were significantly different. There was a rapid increase in the plasma insulin concentration immediately after phase 1 in group II, with maximal plasma insulin concentrations occurring 30 minutes after feeding, followed by a gradual decrease in concentrations throughout the remainder of the study.(ABSTRACT TRUNCATED AT 250 WORDS)
Holste
L C
LC
Department of Small Animal Clinics, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907.
Nelson
R W
RW
Feldman
E C
EC
Bottoms
G D
GD
D000821:Animal Feed; D000818:Animals; D001786:Blood Glucose; D004285:Dogs / Q000097:blood*; D004435:Eating; D005260:Female; D007328:Insulin / Q000097:blood*; D008297:Male; D013997:Time Factors
D001786:Blood Glucose; D007328:Insulin