A retrospective analysis concerning physical aspects and clinical dosimetry in radiosurgery.
The authors have reviewed their experience with treatments of small intracranial lesions by unconventionally fractionated stereotactic radiotherapy using a 4 MV photon beam. Treatment is carried out by multiple non coplanar arc irradiation obtained rotating the target, while kept at the isocentre of a Linac, around a vertical axis. The outmost concentration of the dose within the target volume enables consistent reduction of the amount of the absorbed dose by critical structures of the intact brain. They analyse the dose distribution and the method to optimise the choice of the therapeutic dose. Finally, some radiobiological considerations are presented.
Marchetti
C
C
Servizio di Fisica Sanitaria, Centro di Radiochirurgia della Regione Veneto, U.S.L. n. 8, Vicenza, Italy.
Chierego
G
G
Pozza
F
F
D006801:Humans; D011878:Radiotherapy / Q000379:methods*; D011879:Radiotherapy Dosage; D012189:Retrospective Studies; D013238:Stereotaxic Techniques; D013997:Time Factors