MHC class II invariant chains in antigen processing and presentation.
Most protein antigens cannot elicit a T-cell response unless they are processed to peptides, which are then presented to T lymphocytes by surface MHC class II molecules. Recent evidence supports an essential role of the invariant chain associated with class II MHC polypeptides in antigen processing.
Koch
N
N
Lipp
J
J
Pessara
U
U
Schenck
K
K
Wraight
C
C
Dobberstein
B
B
D000941:Antigens / Q000276:immunology*; D015870:Gene Expression / Q000502:physiology*; D008285:Major Histocompatibility Complex / Q000502:physiology*
D000941:Antigens