The effects of high dose inhaled beclomethasone dipropionate on glucose and lipid profiles in normal and diet controlled diabetic subjects.
We determined the effect of high doses of inhaled beclomethasone dipropionate (2000 micrograms day-1 for two weeks) on the glucose tolerance test, insulin levels, fasting cholesterol and triglyceride concentrations in fourteen normal and ten elderly diet controlled diabetic patients, in a single blind, placebo controlled trial. No significant disturbance of glucose or lipid metabolism was found in either group. This study suggests that at this high dose, BDP does not exhibit significant disturbance of glucose and lipid metabolism after two weeks use.
Ebden
P
P
Department of Medicine, Glenfield General Hospital, Leicester, U.K.
McNally
P
P
Samanta
A
A
Fancourt
G J
GJ
D000280:Administration, Inhalation; D000328:Adult; D000368:Aged; D001507:Beclomethasone / Q000008:administration & dosage*; D001786:Blood Glucose / Q000378:metabolism*; D002986:Clinical Trials as Topic; D003920:Diabetes Mellitus / Q000097:blood*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000097:blood; D008055:Lipids / Q000097:blood*; D008297:Male; D016037:Single-Blind Method
D001786:Blood Glucose; D007328:Insulin; D008055:Lipids; D001507:Beclomethasone