title: [Endocrine, paracrine and autocrine mechanisms of aromatase activity].
abstract: The endocrine, paracrine and autocrine mechanisms involved in aromatase activity. Development of a single follicle during the menstrual cycle is under control of hormones stimulating follicular maturation, ovulation and luteogenesis. Several factors intervene locally to avoid other follicles developing at the same time as the dominant follicle. These other follicles remain quiescent or go on to atresia. Atresia results from the action of several endocrine, paracrine and autocrine mechanisms which synergistically inhibit aromatase activity. The subsequent lack of estrogens reduces granulosa cell multiplication.
authors.affiliation: Institut de Pathologie, C.H.U. Bat. B 23, Université de Liège, Belgique.
authors.forename: P
authors.initials: P
authors.lastname: Franchimont
authors.forename: M T
authors.initials: MT
authors.lastname: Hazee-Hagelstein
authors.forename: C H
authors.initials: CH
authors.lastname: Renard-Charlet
authors.forename: J M
authors.initials: JM
authors.lastname: Jaspar
mesh_terms: D001141:Aromatase / Q000378:metabolism*; D004702:Endocrine Glands / Q000201:enzymology*; D005260:Female; D006801:Humans; D008597:Menstrual Cycle; D010060:Ovulation
chemical_list: D001141:Aromatase
vernacular_title: Mécanismes endocrines, paracrines et autocrines de l'activité aromatasique.