[Clinical results of using Nakom in diseases of the nervous system].
Clinical investigation was performed and dopamine metabolism (renal catecholamine excretion) studied in 29 children and 5 adults with various forms of CP, 5 myasthenic children and 1 child with Strümpel disease treated with Nakom. The therapy was judged expedient in 20% of the cases of pronounced muscular rigidity and dystonia with decreased dopamine excretion. The drug proved ineffective in atonic, astatic, severe hyperkinetic arms, and in cases with severe psycho-organic signs.
Evtushenko
S K
SK
Sadekov
I A
IA
Samsonenko
R A
RA
Mogilevskaia
G S
GS
Prokhorova
L M
LM
Ostropolets
S S
SS
Osadchiĭ
V G
VG
Va'skovskaia
M E
ME
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002230:Carbidopa / Q000627:therapeutic use*; D002395:Catecholamines / Q000652:urine; D002547:Cerebral Palsy / Q000188:drug therapy* / Q000652:urine; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004338:Drug Combinations / Q000627:therapeutic use; D004422:Dystonia Musculorum Deformans / Q000188:drug therapy* / Q000652:urine; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D009127:Muscle Rigidity / Q000188:drug therapy / Q000652:urine; D009157:Myasthenia Gravis / Q000188:drug therapy* / Q000652:urine
D002395:Catecholamines; D004338:Drug Combinations; C009265:carbidopa, levodopa drug combination; D007980:Levodopa; D002230:Carbidopa
Klinicheskie rezu'ltaty primeneniia Nakoma pri zabolevaniiakh nervnoĭ sistemy.