title: [Therapy with L-thyroxine in thyroid struma. Study with ultrasonic evaluation].
abstract: L-thyroxine therapy in thyroid goiter. Study with ultrasound imaging evaluation. The literature contains conflicting reports regarding the treatment of thyroid goiter. We evaluated the efficacy of thyrotropin-suppressive therapy with L-thyroxine to reduce the goiter. We studied two groups of 15 and 19 patients with euthyroid goiter for a period of six months: the former were untreated, the latter received L-thyroxine. Six patients represented the controls. All patients treated had suppressed thyrotropin secretion (as evaluated by immunoradiometric assay); sonography was used to measure the goiter. We found no statistically significant difference in size nodule between the two groups. Therapy was also unable to prevent the formation of new nodules.
authors.forename: M
authors.initials: M
authors.lastname: Peta
authors.forename: S
authors.initials: S
authors.lastname: Cartasegna
authors.forename: M P
authors.initials: MP
authors.lastname: Fabiani
authors.forename: R
authors.initials: R
authors.lastname: Macchi
authors.forename: G
authors.initials: G
authors.lastname: Vecchi
authors.forename: D
authors.initials: D
authors.lastname: Costantino
mesh_terms: D000328:Adult; D000368:Aged; D004341:Drug Evaluation; D005260:Female; D006044:Goiter, Nodular / Q000097:blood / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000627:therapeutic use*; D014463:Ultrasonography
chemical_list: D013972:Thyrotropin; D013974:Thyroxine
vernacular_title: La terapia con L-tiroxina nello struma tiroideo. Studio con valutazione ecotomografica.