Thermoadaptive influence on reactivity pattern of vasopressinergic neurons in the guinea pig.
In cold-adapted guinea pigs, increased amounts of arginine-vasopressin (AVP) immunoreactive material could be visualized in neurons of the supraoptic and paraventricular nucleus, in fibers projecting to the neurohypophysis and in fiber terminals in the ventral lateral septum and in the amygdala. In warm-adapted animals the reactivity to AVP antiserum was poor in all neuronal structures examined. High AVP-immunoreactivity was accompanied by a reduced febrile response to bacterial pyrogen in cold-adapted guinea pigs.
Merker
G
G
Physiologisches Institut der Justus-Liebig-Universität, Giessen, Federal Republic of Germany.
Roth
J
J
Zeisberger
E
E
D000222:Adaptation, Physiological; D000818:Animals; D001127:Arginine Vasopressin / Q000378:metabolism*; D001831:Body Temperature; D001921:Brain / Q000378:metabolism; D004926:Escherichia coli / Q000378:metabolism; D005334:Fever / Q000139:chemically induced; D006168:Guinea Pigs; D009474:Neurons / Q000378:metabolism*; D011749:Pyrogens / Q000494:pharmacology; D013696:Temperature
D011749:Pyrogens; D001127:Arginine Vasopressin