[Comparative effectiveness of intracoronary and systemic thrombolytic therapy of acute myocardial infarction].
Systemic thrombolytic therapy with streptodekase was shown to produce the same effects as intracoronary thrombolytic therapy with avelysine. The blood flow in the coronary vessels could be restored in 72.7% with intracoronary therapy and in 66.7% with systemic thrombolytic therapy. Death rates were 9.1 and 8.9%, respectively, and in 3.1 and 3.3% with reperfusion. A difference was found in the frequency of myocardial infarction-associated complications, depending on the modality of thrombolytic therapy. In the authors' opinion, in clinical institutions where operations on coronary vessels are not supposed to be made after thrombolytic therapy, the systemic thrombolytic therapy with streptodekase should be preferred as it is simplier, safer and easier to apply.
Khalfen
E Sh
ESh
Shtern
S V
SV
Shvarts
I L
IL
Bezrukova
G A
GA
Zolotarev
V A
VA
Rakovskiĭ
M E
ME
D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D003331:Coronary Vessels / Q000187:drug effects; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D013300:Streptokinase / Q000008:administration & dosage*; D015912:Thrombolytic Therapy / Q000379:methods*; D014654:Vascular Patency / Q000187:drug effects
D013300:Streptokinase
Sravnite'lnaia otsenka éffektivnosti intrakoronarnoĭ i sistemnoĭ tromboliticheskoĭ terapii ostrogo infarkta miokarda.