title: IgM--molecular requirements for its assembly and function.
abstract: The conventional model of IgM structure depicts a unique, array of mu, L and J chains, held together by well-defined disulfide bonds and other interactions. Some, but not all, recent data support this model. Here Ann Davis and Marc Shulman review recent, as well as older, studies of IgM and consider their implications for our understanding of IgM structure and function.
authors.forename: A C
authors.initials: AC
authors.lastname: Davis
authors.forename: M J
authors.initials: MJ
authors.lastname: Shulman
mesh_terms: D000818:Animals; D003165:Complement System Proteins / Q000378:metabolism; D004220:Disulfides; D006031:Glycosylation; D006801:Humans; D007075:Immunoglobulin M / Q000378:metabolism*; D015394:Molecular Structure; D008970:Molecular Weight; D011108:Polymers; D011487:Protein Conformation
chemical_list: D004220:Disulfides; D007075:Immunoglobulin M; D011108:Polymers; D003165:Complement System Proteins