Bacterial adherence in urinary tract infections: preliminary studies in a primate model.
Escherichia coli with both P and type 1 fimbriae caused vaginal colonization in the female green monkey, while only the P-fimbriated bacteria frequently caused ascending bladder infection. Bladder inoculation caused only short-lived bladder infection from type 1 fimbriated E. coli, but those with P-fimbriae caused acute pyelonephritis even in the absence of vesicoureteral reflux. Thus, type 1 fimbriae of E. coli, while causing vaginal colonization, did not often cause ascending infection in the non-compromised host as did P-fimbriated bacteria.
Roberts
J A
JA
Department of Urology, Delta Regional Primate Research Center, Covington, LA 70433.
Kaack
M B
MB
Fussell
E N
EN
D000818:Animals; D001422:Bacterial Adhesion; D001770:Blood Bactericidal Activity; D002522:Chlorocebus aethiops; D004195:Disease Models, Animal; D004926:Escherichia coli / Q000145:classification / Q000254:growth & development*; D004927:Escherichia coli Infections / Q000150:complications / Q000209:etiology* / Q000382:microbiology; D005260:Female; D012703:Serotyping; D014552:Urinary Tract Infections / Q000209:etiology* / Q000382:microbiology; D014623:Vaginal Diseases / Q000150:complications*