[Capillary permeability. Fundamental problems and modeling].
This brief paper reviewed some of the most currently used mathematical models in the field of transcapillary exchange. Mathematical formalism was reduced to its simplest expression and a special emphasis was given to the principles and simplifying hypotheses of each kind of model. We described the simplified formulation of capillary-tissue exchange used for the multiple indicator methods and its generalization using the equations derived from thermodynamics. "Black box" models taking into account the complexity of microcirculatory hemodynamics were also presented. We stressed the importance of interactions between adjacent portions of tissue and the potential influence of tissue-lymphatic exchange in the transcapillary exchange phenomenon.
Vicaut
E
E
Laboratoire de Biophysique, Hopital F.-Widal, Paris.
Duvelleroy
M
M
D002199:Capillary Permeability; D006801:Humans; D008955:Models, Cardiovascular
Perméabilité capillaire. Problèmes fondamentaux et modélisation.