title: [Prevention of iron-deficiency anemia in pregnancy using early iron supplementation: a controlled trial].
abstract: An iron supplementation trial versus placebo was performed in double blind on 191 attending at 3 month the antenatal clinic of Poissy maternity. Iron status of mothers and newborns was assessed at 3, 5, 7 month, during the delivery and 2 months after the delivery, using biochemical indicators (hemoglobin level, serum ferritin). The compliance was good in 165 pregnant women (86% of the initial sample): 81 in the iron group, 84 in the placebo group. Among the placebo group, anemia (Hb less than 11 g/dl) was observed at the end of the pregnancy in 30% of women. Depletion of iron stores started at 5 month. In the iron group, hemoglobin level increased significantly during the pregnancy and anemia was observed only in 3% of women at the delivery. Iron status of newborns and two months after delivery was related to mothers iron status at delivery and particularly at the 7th month of pregnancy.
authors.affiliation: Centre de Recherche sur les Anémies Nutritionnelles, CNAM, Paris.
authors.forename: C
authors.initials: C
authors.lastname: De Benaze
authors.forename: P
authors.initials: P
authors.lastname: Galan
authors.forename: R
authors.initials: R
authors.lastname: Wainer
authors.forename: S
authors.initials: S
authors.lastname: Hercberg
mesh_terms: D000328:Adult; D000747:Anemia, Hypochromic / Q000097:blood / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D005293:Ferritins / Q000097:blood; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007501:Iron / Q000627:therapeutic use*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy*
chemical_list: D006454:Hemoglobins; D005293:Ferritins; D007501:Iron
vernacular_title: Prévention de l'anémie ferriprive au cours de la grossesse par une supplémentation martiale précoce: un essai contrôlé.