Translocation of a photoreceptor-specific MEKA protein by light.
Light-or dark-adapted retinal sections from bovine chick and mouse were provided for immunohistochemistry with antiserum against a MEKA protein which is specific to photoreceptor cells. In dark-adapted retinal sections, the anti-MEKA serum heavily stained outer segments of photoreceptor cells and lightly stained inner segments. The reverse staining pattern was observed in light-adapted retinal sections. These results indicate that the translocation of MEKA protein in a photoreceptor cell is regulated by light dark.
Kuo
C H
CH
Department of Pharmacology, Kanazawa University, Japan.
Miki
N
N
D000818:Animals; D001692:Biological Transport / Q000528:radiation effects; D002417:Cattle; D002645:Chickens; D003623:Dark Adaptation; D005136:Eye Proteins / Q000378:metabolism*; D005455:Fluorescent Antibody Technique; D020555:GTP-Binding Protein Regulators; D007150:Immunohistochemistry; D008027:Light; D051379:Mice; D010507:Periodicity; D010750:Phosphoproteins / Q000378:metabolism*; D010786:Photoreceptor Cells / Q000378:metabolism*; D012160:Retina / Q000378:metabolism*
D005136:Eye Proteins; D020555:GTP-Binding Protein Regulators; D010750:Phosphoproteins; C065631:phosducin