[Pyridazinilides (XIV). The action of p-phenyl-phenacyl bromide on 3-phenyl-pyridazine].
This time the synthesis of some new derivatives obtained by the quaternary substitution of one of the heterocyclic nitrogen atoms and by reactions of dipolar cycloaddition is presented. The results of the tests on their antimicrobial and antiinflammatory actions are discussed.
Caproşu
M
M
Ungureanu
M
M
Pavelescu
M
M
Radu
C
C
Petrovanu
M
M
D000098:Acetophenones / Q000138:chemical synthesis / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000494:pharmacology* / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis / Q000494:pharmacology* / Q000627:therapeutic use; D001419:Bacteria / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D004487:Edema / Q000188:drug therapy; D008826:Microbial Sensitivity Tests; D011724:Pyridazines / Q000138:chemical synthesis / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D013329:Structure-Activity Relationship
D000098:Acetophenones; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D011724:Pyridazines; C061455:4-phenylphenacyl bromide; C030818:3-phenylpyridazine
Piridaziniu-ilide (XIV). Acţiunea bromurii de p-fenil-fenacil asupra 3-fenil-piridazinei.