[Effect of calcium antagonists on cerebral and systemic hemodynamics in patients with ischemic disorders of cerebrovascular circulation].
Doppler ultrasound and Evans blue dilution techniques were applied to investigate the corinfar and finoptin effects on cerebral circulation in 97 patients, and on regional circulation in 40 patients with cerebral ischemia. In patients with severe ischemic brain damage, the vasodilating effect without intracerebral stealing was most pronounced. Cardiodepressant effects were negligible. The authors discuss indications and contraindications to finoptin and corinfar treatment in ischemic brain disorders.
Ishchenko
M M
MM
Lobas
V A
VA
D000328:Adult; D000368:Aged; D002545:Brain Ischemia / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D002340:Carotid Artery Diseases / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D002343:Carotid Artery, Internal / Q000187:drug effects; D002560:Cerebrovascular Circulation / Q000187:drug effects* / Q000502:physiology; D002986:Clinical Trials as Topic; D003251:Constriction, Pathologic / Q000188:drug therapy / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D009543:Nifedipine / Q000627:therapeutic use*; D014700:Verapamil / Q000627:therapeutic use*
D014700:Verapamil; D009543:Nifedipine
Vliianie antagonistov ka'ltsiia na tserebra'lnuiu i sistemnuiu gemodinamiku u bo'lnykh s ishemicheskimi narusheniiami mozgovogo krovoobrashcheniia.