Production and interconversion of 1,2-propanediol and hydroxyacetone by Escherichia coli.
The anaerobic metabolism of marginally lethal levels of [13C]formaldehyde by Escherichia coli (K12, MU352, CRB, and CR63) was followed in vivo by 13C NMR. The products include 1,2-propanediol. Under aeration, the 1,2-propanediol is converted to hydroxyacetone. The hydroxyacetone is reconverted to 1,2-propanediol when aeration is stopped. The process can be cycled by varying the rate of aeration.
Commodari
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Department of Chemistry, Queen's University, Kingston, Ont., Canada.
Hunter
B K
BK
D000096:Acetone / Q000031:analogs & derivatives* / Q000378:metabolism; D002478:Cells, Cultured; D004926:Escherichia coli / Q000378:metabolism*; D019946:Propylene Glycol; D011409:Propylene Glycols / Q000378:metabolism*
D011409:Propylene Glycols; D000096:Acetone; D019946:Propylene Glycol; C004433:acetol