Nerve growth factor as a potential treatment in Alzheimer's disease.
An adequate rationale for considering the use of NGF in the treatment of AD exists. Much basic work needs to be done prior to any clinical trials in order to design an ethically and scientifically sound study. The potential use of NGF in patients with AD is a very exciting possibility; enthusiasm should not, however, lead to poorly designed premature clinical trials which are unlikely to provide definitive answers as to the effectiveness of such treatment.
Harbaugh
R E
RE
Section of Neurosurgery, Dartmouth-Hitchcock Medical Center, Hanover, NH 03756.
D000544:Alzheimer Disease / Q000188:drug therapy*; D000818:Animals; D002799:Cholinergic Fibers / Q000187:drug effects; D006801:Humans; D051379:Mice; D009414:Nerve Growth Factors / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*
D009414:Nerve Growth Factors