[Efficacy and tolerability of nimesulide in inflammatory diseases of the genito-urinary system].
In a controlled clinical trial 80 patients of both sexes, aged between 19 and 70 years, with acute or chronic reacutized flogistic bacterial affections of the genito-urinary tract, were randomly assigned to anti-inflammatory treatment with nimesulide (200 mg/day p.o.) or placebo for a mean period of 9 days, in association to the specific antibiotic therapy. In the group treated with nimesulide a significant clinical improvement of the symptomatology was observed in the majority of cases. The therapeutic activity appeared quickly and complete remission of the symptomatology was achieved in a number of cases significantly higher than in the reference group. The tolerability of nimesulide was good.
Corrado
F
F
Corrado
G
G
Fini
M
M
Tomaselli
V
V
Garofalo
F
F
Scaricabarozzi
I
I
D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D001424:Bacterial Infections; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004341:Drug Evaluation; D005260:Female; D005831:Genital Diseases, Female / Q000188:drug therapy* / Q000209:etiology; D005832:Genital Diseases, Male / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D007249:Inflammation / Q000188:drug therapy / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011897:Random Allocation; D013449:Sulfonamides / Q000627:therapeutic use*; D014570:Urologic Diseases / Q000188:drug therapy*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D013449:Sulfonamides; C012655:nimesulide
Efficacia e tollerabilità della nimesulide nelle affezioni flogistiche dell'apparato genito-urinario.