title: [Reiter's syndrome exacerbated by indomethacin].
abstract: A 26-year-old man, with a personal history of drug abuse and positive serology for HIV, had Reiter's syndrome for six years. He experienced progressive worsening of his cutaneous lesions after initiation of indomethacin therapy. The skin lesions were almost completely resolved after the discontinuance of the drug and its reintroduction resulted in a similar deterioration. To our knowledge, indomethacin has not been reported to aggravate Reiter's syndrome. This case study documents anti-inflammatory drugs as possible causal factors for triggering Reiter's syndrome. Possible implicated mechanisms are also discussed.
authors.affiliation: Servicio de Dermatología, Hospital Ramón y Cajal, Madrid.
authors.forename: F
authors.initials: F
authors.lastname: Allegue
authors.forename: P
authors.initials: P
authors.lastname: Boixeda
authors.forename: A
authors.initials: A
authors.lastname: España
authors.forename: R
authors.initials: R
authors.lastname: Moreno
authors.forename: A
authors.initials: A
authors.lastname: Ledo
mesh_terms: D000328:Adult; D016918:Arthritis, Reactive / Q000139:chemically induced* / Q000473:pathology; D006679:HIV Seropositivity / Q000150:complications; D006801:Humans; D007213:Indomethacin / Q000009:adverse effects*; D008297:Male; D012871:Skin Diseases / Q000139:chemically induced* / Q000473:pathology; D013577:Syndrome
chemical_list: D007213:Indomethacin
vernacular_title: Síndrome de Reiter exacerbado por indometacina.