Cephalic insulin release in anorexic women.
Cephalic phase insulin release (CPIR) was examined in women with anorexia nervosa and in lean, age matched controls. Following an overnight fast, a palatable food was presented to subjects and plasma insulin was measured at baseline and every minute for a 10 minute period following the presentation of the food. Elevation in plasma insulin occurred five minutes after food presentation in the anorexic group only. The finding of a significant CPIR in anorexics but not controls was unexpected and tends to rule out a deficient cephalic insulin response as a contributor to the self-starvation observed in anorexia nervosa.
Broberg
D J
DJ
Department of Psychology, University of Washington, Seattle 98195.
Bernstein
I L
IL
D000328:Adult; D000856:Anorexia Nervosa / Q000378:metabolism*; D001835:Body Weight; D005247:Feeding Behavior; D005260:Female; D005502:Food; D006801:Humans; D006815:Hunger; D007328:Insulin / Q000097:blood / Q000378:metabolism*; D000078790:Insulin Secretion; D012903:Smell; D013997:Time Factors; D014796:Visual Perception
D007328:Insulin