title: [Evaluation of the efficacy and tolerability of a fixed dose combination of captopril (CPT) 50 mg and hydrochlorothiazide (HCTZ) 15 mg in the elderly].
abstract: In this double blind study we have evaluated the efficacy and tolerability of the association Captopril 50 mg + hydrochlorothiazide 15 mg/die vs hydrochlorothiazide 25 mg/die in aged patients with hypertension. Both drugs showed a good antihypertensive efficacy, and a better efficacy on diastolic blood pressure was shown by the association Captopril + hydrochlorothiazide.
authors.forename: R
authors.initials: R
authors.lastname: Antonicelli
authors.forename: S
authors.initials: S
authors.lastname: Raffaelli
authors.forename: A
authors.initials: A
authors.lastname: Bossini
authors.forename: E
authors.initials: E
authors.lastname: Paciaroni
authors.forename: P
authors.initials: P
authors.lastname: Zingaretti
authors.forename: G F
authors.initials: GF
authors.lastname: Botta
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002216:Captopril / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D016032:Randomized Controlled Trials as Topic
chemical_list: D006852:Hydrochlorothiazide; D002216:Captopril
vernacular_title: Valutazione dell'efficacia e tollerabilità dell'associazione a dose fissa di captopril (CPT) 50 mg e idroclorotiazide (HCTZ) 15 mg in soggetti anziani.