Pseudomembranous colitis. A clinicopathological review of 7 cases.
The clinical and pathological features of 7 cases of pseudomembranous colitis in which a pathological diagnosis was made on either postmortem or surgical biopsy material are described. All 7 patients had a history of exposure to antibiotics before the onset of the disease, including commonly used antibiotics such as ampicillin. Previous surgery was an additional predisposing factor in 2 patients. All patients presented with diarrhoea. On histological examination the typical 'glandular' lesion showing the surface pseudo-membrane was seen in all cases. In addition, 2 cases showed the typical 'summit' lesions of pseudomembranous colitis.
Bramdev
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Department of Anatomical Pathology, University of Natal, Durban.
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents; D003106:Colon / Q000473:pathology; D003967:Diarrhea / Q000150:complications; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D004761:Enterocolitis, Pseudomembranous / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged
D000900:Anti-Bacterial Agents