title: Histologic findings of Hailey-Hailey disease in a patient with bullous pemphigoid.
abstract: The association of bullous pemphigoid with other immune-mediated diseases has been described; however, coexistence with other bullous dermatoses is unusual. We describe a patient with longstanding localized bullous pemphigoid and the recent finding of a Hailey-Hailey-like histologic pattern in a biopsy specimen obtained at a site of active pemphigoid involvement, as confirmed by immunofluorescence studies. Although this case suggests the possibility of coexistence of two bullous diseases, the Hailey-Hailey-like pattern more likely represents an incidental microscopic finding or a solitary acantholytic lesion.
authors.affiliation: Department of Dermatology, Mayo Clinic, Rochester, MN 55905.
authors.forename: D A
authors.initials: DA
authors.lastname: Mehregan
authors.forename: I J
authors.initials: IJ
authors.lastname: Umbert
authors.forename: M S
authors.initials: MS
authors.lastname: Peters
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005455:Fluorescent Antibody Technique; D006801:Humans; D008297:Male; D010391:Pemphigoid, Bullous / Q000150:complications / Q000473:pathology*; D010392:Pemphigus / Q000150:complications / Q000473:pathology*; D012872:Skin Diseases, Vesiculobullous / Q000473:pathology*