title: Pulmonary surfactant: physiology, pharmacology and clinical uses.
abstract: The endogenous surfactant system in the lungs is complex. The synthetic, recycling and metabolic pathways are clear but the controlling mechanisms are not fully understood. Surfactant-specific proteins are important and their isolation and manufacture opens up new prospects for production of a synthetic surfactant with all the properties of natural human surfactant for therapy and prophylaxis of neonatal respiratory distress syndrome.
authors.affiliation: Royal Hospital for Sick Children, Glasgow.
authors.forename: N S
authors.initials: NS
authors.lastname: Morton
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D011663:Pulmonary Surfactants / Q000494:pharmacology* / Q000627:therapeutic use; D012127:Respiratory Distress Syndrome, Newborn / Q000188:drug therapy*
chemical_list: D011663:Pulmonary Surfactants