title: Tetramine: occurrence in marine organisms and pharmacology.
abstract: The occurrence of tetramethylammonium ion (TMA) in marine organisms is reviewed. The pharmacological action of TMA is also discussed, with special emphasis on the sign and symptoms experienced by oral poisonings. It is concluded that the major manifestations of TMA poisonings may be attributed to interactions with the autonomous nervous system. Fatal intoxications are due to neuromuscular blockade.
authors.affiliation: Marine Chemistry Section, H.C. Orsted Institute, University of Copenhagen, Denmark.
authors.forename: U
authors.initials: U
authors.lastname: Anthoni
authors.forename: L
authors.initials: L
authors.lastname: Bohlin
authors.forename: C
authors.initials: C
authors.lastname: Larsen
authors.forename: P
authors.initials: P
authors.lastname: Nielsen
authors.forename: N H
authors.initials: NH
authors.lastname: Nielsen
authors.forename: C
authors.initials: C
authors.lastname: Christophersen
mesh_terms: D000818:Animals; D001952:Bridged-Ring Compounds / Q000032:analysis* / Q000494:pharmacology / Q000633:toxicity; D008387:Marine Toxins / Q000032:analysis*
chemical_list: D001952:Bridged-Ring Compounds; D008387:Marine Toxins; C010349:tetramethylenedisulfotetramine