Are there location/cage/systematic nontreatment effects in long-term rodent studies? A question revisited.
In the evaluation of long-term rodent studies there are typically several hundred statistical tests employed. A number of techniques can be used to evaluate the multiple resulting p values. After such overall analysis, numerous examples of location/cage/systematic nontreatment effects can be found in long-term studies.
Young
S S
SS
Glaxo Inc., Research Triangle Park, North Carolina 27709.
D000818:Animals; D000830:Animals, Laboratory / Q000502:physiology*; D012107:Research Design; D014116:Toxicology / Q000592:standards*