[Calcium inhibitors and arterial hypertension].
Calcium inhibitors decrease blood pressure and improve different functional and structural cardiovascular parameters of heart and vessels. Thus different calcium antagonists lead to variable changes of cardiac flow with reduction of cardiac hypertrophy and modifications of heart rate and inotropism. Their peripheral action on large arteries and arterioles can create a vasodilation with elevation of blood velocity and flow. An improvement in arterial and venous compliance is also observed.
Hugue
C
C
Centre de diagnostic et Centre de recherche de l'hypertension artérielle, Hôpital Broussais, Paris.
Safar
M
M
D001158:Arteries / Q000187:drug effects / Q000503:physiopathology; D001160:Arterioles / Q000187:drug effects / Q000503:physiopathology; D002121:Calcium Channel Blockers / Q000494:pharmacology / Q000627:therapeutic use*; D006321:Heart / Q000187:drug effects / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D014664:Vasodilation / Q000187:drug effects; D014680:Veins / Q000187:drug effects / Q000503:physiopathology
D002121:Calcium Channel Blockers
Inhibiteurs calciques et hypertension artérielle.