title: [Partial lipodystrophy and membranoproliferative glomerulonephritis. Apropos of a case].
abstract: We have studied a girl seven and a half years old with a renal disease manifested by proteinuria and nephrotic syndrome combined with initial macroscopic hematuria normal blood pressure and persistent depression of the complement C3 levels with the complement activating gamma globulin (C3 Nef) present in serum. The anatomopathological study showed findings of membranoproliferative glomerulonephritis type II with intramembranous deposit (dense deposit disease). An unusual association with partial lipodystrophy was present in this case. A follow-up of five years, and a few considerations about etiopathogenic theories were presented.
authors.affiliation: Sección de Nefrologia, Hospital Nacional Infantil, Niño Jesús, Madrid.
authors.forename: M J
authors.initials: MJ
authors.lastname: Martínez Debora
authors.forename: M
authors.initials: M
authors.lastname: Vázquez Martul
authors.forename: J L
authors.initials: JL
authors.lastname: Ecija Peiró
authors.forename: J
authors.initials: J
authors.lastname: González Pérez
authors.forename: J
authors.initials: J
authors.lastname: Lirio Rodríguez
authors.forename: I
authors.initials: I
authors.lastname: González Mediero
mesh_terms: D002648:Child; D003176:Complement C3 / Q000032:analysis; D003178:Complement C3 Nephritic Factor / Q000032:analysis; D005260:Female; D015432:Glomerulonephritis, Membranoproliferative / Q000150:complications*; D006801:Humans; D008060:Lipodystrophy / Q000150:complications*
chemical_list: D003176:Complement C3; D003178:Complement C3 Nephritic Factor
vernacular_title: Lipodistrofia parcial y glomerulonefritis membranoproliferativa. A propósito de un caso.