title: Immunotherapy of malignant gliomas.
abstract: Some recent immunological approaches to therapy of cancer are briefly considered. The possibility of the application of immunotherapy to malignant gliomas was investigated in vitro, evaluating the cytotoxic activity of Interleukin-2-activated lymphocytes against cultured human glioma cells. The possibility of generating valid cytotoxic effectors from glioma patients peripheral blood was also investigated in consideration of the immunological alterations reported in such patients.
authors.affiliation: Dipartimento di Scienze Neurologiche, Università degli Studi di Roma La Sapienza, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Maleci
mesh_terms: D001932:Brain Neoplasms / Q000276:immunology / Q000628:therapy*; D003602:Cytotoxicity, Immunologic; D005910:Glioma / Q000276:immunology / Q000628:therapy*; D006801:Humans; D007167:Immunotherapy / Q000379:methods; D007376:Interleukin-2 / Q000494:pharmacology; D014407:Tumor Cells, Cultured
chemical_list: D007376:Interleukin-2