title: [Use of carbamazepine in trigeminal neuralgia].
abstract: The treatment efficiency was compared to blood carbamazepine++ levels in patients with trigeminal neuralgia which were treated with the drug over a long period. The parameters displayed a good (r = 0.70) correlation that resulted in a tendency to increase treatment effect with carbamazepine++ plasma concentration increase. The treatment proved most efficient and side effect-free in a concentration range of 5 to 10 micrograms/ml. The data on blood carbamazepine++ concentrations may be helpful in designing a controlled course of treatment.
authors.forename: M n
authors.initials: Mn
authors.lastname: Puzin
authors.forename: L A
authors.initials: LA
authors.lastname: Martynova
authors.forename: M N
authors.initials: MN
authors.lastname: Sharov
authors.forename: V P
authors.initials: VP
authors.lastname: Zherdev
authors.forename: I A
authors.initials: IA
authors.lastname: Starose'lskaia
mesh_terms: D000328:Adult; D000368:Aged; D001711:Biotransformation; D002220:Carbamazepine / Q000008:administration & dosage* / Q000097:blood / Q000493:pharmacokinetics; D002986:Clinical Trials as Topic; D004305:Dose-Response Relationship, Drug; D005260:Female; D006207:Half-Life; D006801:Humans; D008297:Male; D008875:Middle Aged; D014277:Trigeminal Neuralgia / Q000188:drug therapy* / Q000378:metabolism
chemical_list: D002220:Carbamazepine
vernacular_title: Primenenie karbamazepina pri nevralgii troĭnichnogo nerva.