title: [Clinical trial of the laksafer preparation on patients following gynecological operations].
abstract: An original Bulgarian phyto-preparation laxafer was used in 97 women, operated for gynecological complaints, with the aim to overcome postoperative paresis of intestines and recovery of peristalsis within the first ten postoperative days. It was established that the preparation, given from the second postoperative day in a dose of 2-4 pills daily in women, operated by nonabdominal approach due to the fact that the abdominal cavity was not open during the operation and intestinal peristalsis, was preserved to a great degree. In women, operated by abdominal approach, the optimal time for the onset of treatment was the third postoperative day in a dose of 3 pills daily. The most frequent effect side effect was swelling of the abdomen, which was observed usually during the first day since the onset of treatment. The side effects were minimal after the second day, but they disappeared completely on the fifth postoperative day.
authors.forename: N
authors.initials: N
authors.lastname: Doganov
authors.forename: N
authors.initials: N
authors.lastname: Negentsov
mesh_terms: D002986:Clinical Trials as Topic; D003672:Defecation / Q000187:drug effects; D004338:Drug Combinations; D005260:Female; D005831:Genital Diseases, Female / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D010528:Peristalsis / Q000187:drug effects; D010936:Plant Extracts / Q000009:adverse effects / Q000627:therapeutic use*; D011182:Postoperative Care; D013607:Tablets; D013997:Time Factors
chemical_list: D004338:Drug Combinations; D010936:Plant Extracts; D013607:Tablets; C060699:laksafer
vernacular_title: Klinichno izpitvane na preparata laksafer na patsientki sled ginekologichni operatsii.