Left ventricular diastolic dysfunction and cardiovascular regulation in hypertension.
The determinants and physiologic consequences of altered left ventricular diastolic filling rate in hypertension has not yet been fully assessed. Data suggesting that left ventricular diastolic dysfunction in hypertension is associated with impaired peripheral vascular regulation by cardiopulmonary reflexes has been reported recently. Other functional correlates of alteration of left ventricular diastolic function are reviewed, as well as the effects of antihypertensive therapy on the rate of left ventricular filling.
Fouad-Tarazi
F M
FM
Department of Heart and Hypertension Research, Cleveland Clinic Foundation, Ohio 44195-5069.
D003971:Diastole / Q000502:physiology*; D006321:Heart / Q000503:physiopathology*; D006352:Heart Ventricles; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D009200:Myocardial Contraction / Q000502:physiology*