Fine-tuning of MHC class II gene expression in defined microenvironments.
Strict control of major histocompatibility complex class II gene expression is essential for proper functioning of the immune system. Recent transgenic mouse studies have revealed an intricate fine-tuning of class II gene transcription in microenvironments such as the germinal centers and thymic cortex and medulla.
Fehling
H J
HJ
Viville
S
S
van Ewijk
W
W
Benoist
C
C
Mathis
D
D
D000818:Animals; D001921:Brain / Q000276:immunology; D005786:Gene Expression Regulation; D000949:Histocompatibility Antigens Class II / Q000235:genetics*; D008214:Lymphocytes / Q000276:immunology; D008285:Major Histocompatibility Complex; D051379:Mice; D008822:Mice, Transgenic
D000949:Histocompatibility Antigens Class II