title: Nosocomial infections due to Serratia marcescens--clinical findings, antibiotic susceptibility patterns and fine typing.
abstract: We report on nosocomial infections caused by Serratia marcescens occurring in a neonatal intensive care unit and a children's ward for cardiac intensive care. According to the plasmid pattern analysis, all isolated epidemic strains belonged to one clone. Multi-drug resistance, even to cephalosporins of the third generation and amikacin, was characteristic for all strains. Certain markers of S. marcescens (haemolysin, proteases, siderophores) which are thought to be related to virulence were studied but will require further investigation.
authors.affiliation: Institut für Medizinische Mikrobiologie, Humboldt Universität zu Berlin Charité, DDR.
authors.forename: R
authors.initials: R
authors.lastname: Bollmann
authors.forename: E
authors.initials: E
authors.lastname: Halle
authors.forename: W
authors.initials: W
authors.lastname: Sokolowska-Köhler
authors.forename: E L
authors.initials: EL
authors.lastname: Grauel
authors.forename: P
authors.initials: P
authors.lastname: Buchholz
authors.forename: I
authors.initials: I
authors.lastname: Klare
authors.forename: H
authors.initials: H
authors.lastname: Tschäpe
authors.forename: W
authors.initials: W
authors.lastname: Witte
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D015373:Bacterial Typing Techniques; D001604:Berlin; D003428:Cross Infection / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D004196:Disease Outbreaks; D004352:Drug Resistance, Microbial; D004756:Enterobacteriaceae Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D015278:Intensive Care Units, Pediatric; D008297:Male; D010957:Plasmids; D011446:Prospective Studies; D012189:Retrospective Studies; D012706:Serratia marcescens
chemical_list: D000900:Anti-Bacterial Agents