The cell-bound hemolysin of Serratia marcescens contributes to uropathogenicity.
The contribution of the cell-bound hemolysin of Serratia marcescens to uropathogenicity was studied in an experimental urinary tract infection in rats. The strain carrying the Serratia hemolysin colonized the urinary tract more and lead to a stronger inflammatory response compared to the isogenic hemolysin negative strain.
Marre
R
R
Institut für Medizinische Mikrobiologie der Medizinischen Universität zu Lübeck, F.R.G.
Hacker
J
J
Braun
V
V
D000818:Animals; D001426:Bacterial Proteins / Q000378:metabolism; D006460:Hemolysin Proteins / Q000502:physiology*; D007668:Kidney / Q000382:microbiology; D051381:Rats; D011994:Recombinant Proteins / Q000378:metabolism; D012706:Serratia marcescens / Q000472:pathogenicity*; D001743:Urinary Bladder / Q000382:microbiology; D014552:Urinary Tract Infections / Q000382:microbiology*
D001426:Bacterial Proteins; D006460:Hemolysin Proteins; D011994:Recombinant Proteins