[Multiple gastric carcinoids, atrophic gastritis, hypergastrinemia: a confirmed association (a new case)].
Although carcinoid tumors only infrequently (2-6%) have a gastric localization, in recent years several cases have been described of this tpe of neoplasm in association with atrophic gastritis (with or without pernicious anemia). A possible carcinogenetic effect of sustained hypergastrinemia on the enterochromaffin-like cells (ECL) of the gastric mucosa has been postulated. A new case of these characteristics in reported, and a review is made of the pathogenic hypotheses in the literature on this peculiar type of tumors and their possible clinical implications.
González Martín
J A
JA
De Miguel
R
R
Martínez Montiel
M P
MP
Pérez Sola
A
A
Razquin
J
J
Calvo
A
A
Saiz
F
F
D000328:Adult; D002276:Carcinoid Tumor / Q000097:blood / Q000150:complications* / Q000473:pathology; D005755:Gastrins / Q000097:blood*; D005756:Gastritis / Q000150:complications*; D005757:Gastritis, Atrophic / Q000097:blood / Q000150:complications*; D006801:Humans; D008297:Male; D013274:Stomach Neoplasms / Q000097:blood / Q000150:complications* / Q000473:pathology
D005755:Gastrins
Carcinoides gástricos múltiples, gastritis atrófica, hipergastrinemia: una asociación que se confirma (un nuevo caso).