A review of natural products and plants as potential antidiabetic drugs.
The present paper reviews the active, natural principles and crude extracts of plants which have been experimentally studied for hypoglycemic activity in the last ten years. Phytoconstituents with known structures have been classified in appropriate chemical groups and the active crude extracts have been listed alphabetically according to genus. Data are reported on their pharmacological activity, mechanism of action, toxicity and other properties.
Ivorra
M D
MD
Department de Farmacologia i Farmacotecnia, Farmacognosia i Farmacodinamia, Facultat de Farmacia, Universitat de Valencia, Spain.
Payá
M
M
Villar
A
A
D000818:Animals; D003920:Diabetes Mellitus / Q000188:drug therapy; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy; D004353:Drug Evaluation, Preclinical; D006801:Humans; D007004:Hypoglycemic Agents / Q000494:pharmacology / Q000633:toxicity; D008519:Medicine, Traditional; D010936:Plant Extracts / Q000494:pharmacology / Q000633:toxicity; D010946:Plants, Medicinal; D051381:Rats
D007004:Hypoglycemic Agents; D010936:Plant Extracts