title: [Captopril from Pharmachem in the treatment of arterial hypertension].
abstract: 30 hypertensive patients were treated in outpatients conditions for a 6 month period with captopril "Pharmachem". The patients were classified in accordance with the degree of the arterial hypertension into three groups: light hypertension--II patients, moderate hypertension 13 patients and severe hypertension--6 patients. Captopril was applied the first two weeks in a dose of 25 mg 3 times daily. When there was no effect the dose was increased every two weeks with 25 mg daily up to a 150 mg daily dose. A very good result was achieved in 11 patients (36.7%) and in 15 patients (50%) the result was considered good. In 4 patients the arterial pressure fell to normal after the addition of chlorthalidone. The following side effects were observed: decrease of the leucocyte number in reference ranges, insignificant increase of the uric acid in reference ranges, proteinuria below 1 gr/24 h. Captopril "Pharmachem" applied alone or in combination with a diuretic is a very efficient drug for the treatment of all stages of arterial hypertension.
authors.forename: D
authors.initials: D
authors.lastname: Monova
authors.forename: N
authors.initials: N
authors.lastname: Belovezhdov
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D002216:Captopril / Q000627:therapeutic use*; D002752:Chlorthalidone / Q000627:therapeutic use; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D013607:Tablets; D013997:Time Factors
chemical_list: D013607:Tablets; D002216:Captopril; D002752:Chlorthalidone
vernacular_title: Kaptopril "Farmakhim" pri lechenie na arterialnata khipertoniia.