Differentiation of preadipocytes is regulated by insulin-like growth factor-1.
Preadipocytes converted to adipocytes when insulin-like growth factor-1 or insulin was added to a medium depleted of those compounds. A variety of mRNA molecules characteristic of the adipocytes were induced.
D000273:Adipose Tissue / Q000166:cytology*; D000818:Animals; D002417:Cattle; D002454:Cell Differentiation; D002478:Cells, Cultured; D007334:Insulin-Like Growth Factor I / Q000494:pharmacology*; D051381:Rats; D013002:Somatomedins / Q000494:pharmacology*
D013002:Somatomedins; D007334:Insulin-Like Growth Factor I