[Changes in the renin-angiotensin-aldosterone system in elderly patients with chronic ischemic heart disease. 3. The renin-angiotensin-aldosterone system in elderly patients with ischemic heart disease without cardiovascular failure].
As shown by the results of the investigation, there is a moderate rise in renin-angiotensin-aldosterone system activity in the elderly patients suffering from chronic IHK under normal conditions of life: basal level, changes in plasma renin activity and circulating aldosterone concentration during a 24-hour period and in response to the orthostasis. Considerable disturbances of the functional state of the renin-angiotensin-aldosterone system are seen with a physical load of the submaximal intensity. The data obtained indicate pathogenetic significance of the above changes which should be taken into consideration while prescribing therapy of such patients.
Korkusko
V
V
Institut für Gerontologie, Akademie der Medizinischen Wissenschaften der UdSSR, Kiew.
Kalinovskaja
E G
EG
Fedirko
M I
MI
Gidzinskaja
I N
IN
D000368:Aged; D002216:Captopril / Q000627:therapeutic use; D002940:Circadian Rhythm; D003327:Coronary Disease / Q000188:drug therapy / Q000503:physiopathology*; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006333:Heart Failure / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000097:blood; D011187:Posture; D012084:Renin-Angiotensin System / Q000187:drug effects
D002216:Captopril
Veränderungen des Renin-Angiotensin-Aldesteron-Systems (RAAS) bei älteren Patienten mit chronischer ischämischer Herzkrankheit (IHK). 3. Mitteilung. Das Renin-Angiotensin-Aldosteron-System bei ältern IHK-Patienten ohne Herz-Kreislauf-Insuffizienz.