title: Formation of endothelin by cultured airway epithelial cells.
abstract: Immunoreactivity to endothelin was detected in conditioned culture medium from both canine and porcine tracheal epithelial cells. Gel permeation chromatography and fast protein liquid chromatography were used to confirm the identity of the endothelin. The two peaks demonstrated on fast protein liquid chromatography co-eluted with endothelin 1 and endothelin 3 respectively.
authors.affiliation: Department of Clinical Pharmacology, Royal Postgraduate Medical School, London, England.
authors.forename: P N
authors.initials: PN
authors.lastname: Black
authors.forename: M A
authors.initials: MA
authors.lastname: Ghatei
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
authors.forename: D
authors.initials: D
authors.lastname: Bretherton-Watt
authors.forename: T
authors.initials: T
authors.lastname: Krausz
authors.forename: C T
authors.initials: CT
authors.lastname: Dollery
authors.forename: S R
authors.initials: SR
authors.lastname: Bloom
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D004285:Dogs; D016232:Endothelins; D004727:Endothelium / Q000378:metabolism; D010452:Peptide Biosynthesis; D010455:Peptides / Q000302:isolation & purification; D011863:Radioimmunoassay; D013552:Swine; D014132:Trachea / Q000378:metabolism*
chemical_list: D016232:Endothelins; D010455:Peptides