title: The Yersinia yop regulon.
abstract: Growth of yersiniae is restricted at 37 degrees C in the absence of calcium ions. This phenomenon correlates with the massive release of a set of proteins called Yops. Growth restriction and Yops production are governed by a 70 kb plasmid called pYV. yop genes are distributed throughout pYV and constitute a thermoactivated regulon controlled by the gene virF. The transcription activator VirF is a member of a new family of regulators including those of the arabinose and rhamnose operons as well as a regulator of enteric colonization pili. The role of calcium ions on the release of Yops remains largely unknown.
authors.affiliation: Unité de Microbiologie, Université Catholique de Louvain, Brussels, Belgium.
authors.forename: G R
authors.initials: GR
authors.lastname: Cornelis
authors.forename: T
authors.initials: T
authors.lastname: Biot
authors.forename: C
authors.initials: C
authors.lastname: Lambert de Rouvroit
authors.forename: T
authors.initials: T
authors.lastname: Michiels
authors.forename: B
authors.initials: B
authors.lastname: Mulder
authors.forename: C
authors.initials: C
authors.lastname: Sluiters
authors.forename: M P
authors.initials: MP
authors.lastname: Sory
authors.forename: M
authors.initials: M
authors.lastname: Van Bouchaute
authors.forename: J C
authors.initials: JC
authors.lastname: Vanooteghem
mesh_terms: D001422:Bacterial Adhesion; D001425:Bacterial Outer Membrane Proteins / Q000032:analysis; D001426:Bacterial Proteins / Q000096:biosynthesis / Q000235:genetics*; D002118:Calcium / Q000502:physiology; D015964:Gene Expression Regulation, Bacterial; D005809:Genes, Regulator / Q000502:physiology; D015007:Yersinia / Q000235:genetics* / Q000472:pathogenicity
chemical_list: D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; C055819:Yop5 (Yersinia); D002118:Calcium