Multiple systems organ failure (MSOF): lessons learned from the adult respiratory distress syndrome (ARDS).
The relationship between ARDS and MSOF is explored. Models include that ARDS represents only one organ failing in MSOF, or that MSOF is a complication of ARDS owing to the development of infection and sepsis syndrome in these patients. Data are reviewed suggesting an important role of infection and sepsis syndrome in both models.
Hudson
L D
LD
Division of Pulmonary and Critical Care Medicine, University of Washington, Seattle.
D006801:Humans; D007239:Infections / Q000150:complications; D009102:Multiple Organ Failure / Q000503:physiopathology*; D012128:Respiratory Distress Syndrome / Q000150:complications / Q000503:physiopathology*; D018805:Sepsis / Q000150:complications / Q000503:physiopathology*