[Isolation and properties of hybridomas producing monoclonal antibodies to the Leningrad-16 measles virus].
A panel of 18 hybridomas producing MCA to measles virus (the L-16 strain) was produced by somatic hybridization method. Thirteen hybridomas produce immunoglobulins of the G class represented by all known subclasses of mouse immunoglobulins; the subclass G 2a is predominant. Five hybridomas produce immunoglobulins of the M class. The resulting preparations of MCA are highly reactive in several serological tests: IFA, NIF, HI, NT. MCA have been divided into 3 groups according to their capacity to combine with three strains of morbilli viruses: L-16, LEC, and carnivora distemper virus (strain EPM).
Andzhaparidze
O G
OG
Nagieva
F G
FG
Mal'tseva
N N
NN
Vedunova
S L
SL
Zvonarev
A Iu
AIu
D000818:Animals; D000911:Antibodies, Monoclonal / Q000032:analysis / Q000096:biosynthesis*; D000918:Antibody Specificity; D001202:Ascitic Fluid / Q000276:immunology; D002459:Cell Fusion; D005455:Fluorescent Antibody Technique; D006825:Hybridomas / Q000276:immunology*; D007114:Immunization / Q000379:methods; D007136:Immunoglobulins / Q000032:analysis / Q000096:biosynthesis; D008459:Measles virus / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D009500:Neutralization Tests; D014709:Vero Cells
D000911:Antibodies, Monoclonal; D007136:Immunoglobulins
Poluchenie i svoĭstva gibridom, produtsiruiushchikh monoklonal'nye antitela k virusu kori Leningrad-16.