title: The porphyrias.
abstract: The importance of recognizing these rare metabolic disorders in the Emergency Department patient is discussed. The pathophysiologic mechanisms behind the neurologic and cutaneous manifestations of these disorders is reviewed; presentation and management of the acute hepatic porphyrias are described; and features of the erythropoietic porphyrias and porphyria cutanea tarda are presented.
authors.affiliation: Division of Emergency Medicine, Ohio State University School of Medicine, Columbus.
authors.forename: H A
authors.initials: HA
authors.lastname: Werman
mesh_terms: D000208:Acute Disease; D004920:Erythropoiesis; D006418:Heme / Q000096:biosynthesis; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D011164:Porphyrias / Q000175:diagnosis / Q000378:metabolism / Q000503:physiopathology; D012871:Skin Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy
chemical_list: D006418:Heme