[Acute submassive cholestatic hepatitis after treatment with carbimazole. Presentation of a new case and review of the literature].
Carbimazole, an antithyroid agent of the thioimidazole group, can induce unpredictable liver alterations, presumably by hypersensitivity. We describe the case of a hyperthyroid woman who suffered acute submassive cholestatic hepatitis in the course of treatment with this drug. We also review the other seven cases of carbimazole hepatotoxicity previously communicated in the literature.
Moreno Sánchez
D
D
Medina Asensio
J
J
Colina Ruiz-Delgado
F
F
Campos Cantero
R
R
Crespo Rincón
L
L
Belda Serna
A
A
D000208:Acute Disease; D000368:Aged; D002231:Carbimazole / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000150:complications / Q000209:etiology* / Q000473:pathology; D002779:Cholestasis / Q000139:chemically induced* / Q000150:complications / Q000473:pathology; D005260:Female; D006801:Humans
D002231:Carbimazole
Hepatitis colestásica aguda submasiva tras tratamiento con carbimazol. Aportación de un caso y revisión de la literatura.