[Therapy of aging skin].
The process of involution of aging skin is essentially caused by functional changes progressing as a consequence of the chronic influence of exogenous noxae. Reasonably, prophylaxis should avoid actinic damages, and skin care should be adapted to the changes due to age, which means providing a substitute for cutaneous lipids and stabilizing the hydration of the horny layer. Placebo-controlled studies proved that topical treatment with 0.05% tretinoin can result in the regression of degenerative and precancerous changes of the senile skin caused by chronic exposure to UVB. However, long-term results remain to be seen.
Roeser
B E
BE
Hautklinik der Städt, Kliniken Dortmund.
Budde
J
J
Tronnier
H
H
D000368:Aged; D004249:DNA Damage; D004260:DNA Repair / Q000187:drug effects*; D006801:Humans; D009381:Neoplasms, Radiation-Induced / Q000517:prevention & control; D015595:Skin Aging / Q000187:drug effects*; D012878:Skin Neoplasms / Q000517:prevention & control; D014212:Tretinoin / Q000008:administration & dosage*
D014212:Tretinoin
Therapie der Altershaut.