title: [Brofaromine--a selective, reversible and short-acting MAO-A inhibitor].
abstract: During the last years the MAO-inhibitors reached a progressive importance in clinical practice. It was attempted to solve problems of tolerability by a new generation of MAO-inhibitors. Brofaromine is a MAO-inhibitor of the second generation, a selective, reversible and short acting MAO-A-inhibitor, promising that the dangerous "cheese effect" will occur only under extreme conditions. The clinical trials performed hitherto, among other double-blind test versus tranylcypromine and imipramine, demonstrate a good antidepressive efficacy and a good tolerability.
authors.affiliation: Universitätsnervenklinik Bonn.
authors.forename: H J
authors.initials: HJ
authors.lastname: Möller
authors.forename: G
authors.initials: G
authors.lastname: Wendt
mesh_terms: D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003866:Depressive Disorder / Q000188:drug therapy*; D004311:Double-Blind Method; D006801:Humans; D010880:Piperidines / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D000928:Antidepressive Agents; D010880:Piperidines; C038213:brofaromine
vernacular_title: Brofaromin--ein selektiver, reversibler und kurzwirksamer MAO-A-Hemmer.