title: Expression of ribosomal protein genes and regulation of ribosome biosynthesis in Xenopus development.
abstract: Studies on ribosome biosynthesis in developing Xenopus oocytes and embryos, and after microinjection of cloned ribosomal-protein genes, have revealed that the synthesis of ribosomal proteins (r-proteins) is controlled by two types of regulation: (1) a post-transcriptional regulation, operated by feedback of the r-proteins themselves, controls processing and stability of r-protein transcripts and thus the amount of the corresponding mRNA present in the cell; and (2) a translational regulation controls the efficiency of utilization of r-protein mRNA (rp-mRNA) in response to the cellular needs for new ribosomes.
authors.forename: F
authors.initials: F
authors.lastname: Amaldi
authors.forename: I
authors.initials: I
authors.lastname: Bozzoni
authors.forename: E
authors.initials: E
authors.lastname: Beccari
authors.forename: P
authors.initials: P
authors.lastname: Pierandrei-Amaldi
mesh_terms: D000818:Animals; D012269:Ribosomal Proteins / Q000096:biosynthesis*; D012270:Ribosomes / Q000378:metabolism*; D014981:Xenopus / Q000235:genetics*
chemical_list: D012269:Ribosomal Proteins