title: Raynaud's phenomenon and disease.
abstract: Maurice Raynaud initiated the discussion of cold-induced vasospasm over 125 years ago. Research has shown that the physiology of Raynaud's involves a complex interaction in both local and systemic factors. Although a multitude of laboratory tests are available to help evaluate the prognosis of Raynaud's phenomenon, patient history remains the most reliable method of diagnosis. There are a variety of treatment modalities available. The treatment program should be tailored to the severity and etiology of the disease.
authors.affiliation: Department of Dermatology, Henry Ford Hospital, Detroit, Michigan.
authors.forename: M B
authors.initials: MB
authors.lastname: Cardelli
authors.forename: D M
authors.initials: DM
authors.lastname: Kleinsmith
mesh_terms: D006801:Humans; D011928:Raynaud Disease / Q000175:diagnosis / Q000209:etiology / Q000628:therapy