Expression of interleukin-2 receptor (IL-2R) in feline peripheral blood lymphocytes.
A monoclonal anti-interleukin-2 receptor (IL-2R) antibody has been identified as a putative antibody against the human IL-2R. In the present study, anti-Tac antibody CD-25 was used to determine cell expressing IL-2 receptor in feline peripheral blood lymphocytes by means of direct immunofluorescence tests and complement-mediated lymphocytotoxicity tests. With complement-mediated lymphocytotoxicity, approximately 18% of feline peripheral blood lymphocytes expressed the receptors. By the direct immunofluorescence test, we found approximately 22% of IL-2R positive cells in lymphocytes of feline peripheral-blood.
Iwamoto
K
K
Takeishi
M
M
Takagi
K
K
Yukawa
M
M
Kuyama
T
T
Ishida
M
M
Kuramochi
T
T
D000818:Animals; D000911:Antibodies, Monoclonal; D002415:Cats; D003168:Complement Fixation Tests; D003602:Cytotoxicity, Immunologic; D005455:Fluorescent Antibody Technique; D008214:Lymphocytes / Q000276:immunology*; D015375:Receptors, Interleukin-2 / Q000032:analysis*
D000911:Antibodies, Monoclonal; D015375:Receptors, Interleukin-2