[Characteristics of hormonal regulation in patients with ischemic heart disease after the insulin test combined with physical load].
Nine normal subjects and 6 coronary patients (aged 26 to 53 years) who had survived myocardial infarction more than 3 years before and showed no clinical signs of heart failure, obesity, hypertension and diabetes mellitus, while having normal glucose tolerance test values, were exposed to the insulin test in combination with physical stress in the presence of clinically manifest hypoglycemia. Plasma and erythrocyte glucose and immunoreactive insulin, and urinary excretion of catecholamines were measured. Coronary patients showed considerably increased erythrocyte immunoreactive insulin levels, recorded immediately upon discontinuation of exercise, while their sympathoadrenal hormonal activation was less significant, as compared to normal subjects. The combination of the insulin test and exercise in coronary patients with normal glucose tolerance values helps to detect disturbances of regulatory mechanisms at the erythrocyte level and can be used as an adjuvant method for the assessment of latent carbohydrate metabolic disorders.
Sokolov
E I
EI
Zaev
A P
AP
Khovanskaia
T P
TP
Velichkina
S V
SV
Zhizhina
S A
SA
D000328:Adult; D001786:Blood Glucose / Q000032:analysis*; D002395:Catecholamines / Q000652:urine*; D003327:Coronary Disease / Q000378:metabolism*; D004912:Erythrocytes / Q000378:metabolism*; D005080:Exercise Test; D005951:Glucose Tolerance Test; D006801:Humans; D007003:Hypoglycemia / Q000209:etiology; D007328:Insulin / Q000008:administration & dosage / Q000097:blood*; D008297:Male; D008875:Middle Aged
D001786:Blood Glucose; D002395:Catecholamines; D007328:Insulin
Osobennosti gormonal'noĭ reguliatsii u bol'nykh ishemicheskoĭ bolezn'iu serdtsa pri sochetannom vozdeĭstvii insulinovoĭ proby i fizicheskoĭ nagruzki.