[The significance of a change in the calcitonin level of the blood in various carbohydrate metabolic states in the ontogeny of rats].
A study was made of the plasma levels of total calcium and calcitonin activity (CT-activity) in rats of different age groups in insulin hypoglycemia and glucose tolerance per os. An increase in a CT-activity value and a decrease in plasma concentration of total calcium in rats of all age groups were defined in hypo- and hyperglycemia. Age specificities of CT secretion and hypocalcemia were demonstrated. More noticeable hypocalcemia in GTT and more intensive changes in CT secretion and hypocalcemia in insulin hypoglycemia were detected in immature rats than in adult and old rats. A conclusion was made that the biological significance of a rise of CT in different conditions of carbohydrate metabolism was body calcium saving.
Iaroshevskkiĭ
Iu A
IuA
Butakova
S S
SS
Darinskiĭ
Iu A
IuA
D000375:Aging / Q000097:blood*; D000818:Animals; D002116:Calcitonin / Q000097:blood* / Q000378:metabolism; D002118:Calcium / Q000097:blood; D002241:Carbohydrates / Q000097:blood*; D005947:Glucose / Q000008:administration & dosage; D007003:Hypoglycemia / Q000097:blood / Q000139:chemically induced; D007328:Insulin / Q000494:pharmacology; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D002241:Carbohydrates; D007328:Insulin; D002116:Calcitonin; D005947:Glucose; D002118:Calcium
Znachenie izmeneniia urovnia kal'tsitonina v krovi pri razlichnykh sostoianiiakh uglevodnogo obmena v ontogeneze u krys.