title: An update on digoxin.
abstract: This review deals briefly with recent developments in the therapeutic drug monitoring of digoxin. Strategies for decreasing the interference by digoxin metabolites, digoxin-like factors, and spironolactone metabolites in immunoassays of digoxin are discussed. Other issues addressed include the development of alternative methods of analysis, such as receptor assays and "high-pressure" liquid chromatography; digoxin-like factors in hypertension; drug-drug interactions; redistribution of digoxin stores in the body; and forensic considerations.
authors.affiliation: Children's Hospital National Medical Center Research Foundation, Washington, DC 20010.
authors.forename: J A
authors.initials: JA
authors.lastname: Stone
authors.forename: S J
authors.initials: SJ
authors.lastname: Soldin
mesh_terms: D004077:Digoxin / Q000627:therapeutic use*; D006801:Humans; D008991:Monitoring, Physiologic
chemical_list: D004077:Digoxin