title: An ethnopharmacognostic approach to the search for immunomodulators of plant origin.
abstract: The search for immunomodulating plant constituents through basic and field inquiries into the literature and practices of traditional Indian medicine is treated. The strategy of data collecting proceeds through aspects of an ethnobotanical, an ethnopharmaceutical, an ethnopharmacological, and an ethnomedical nature. In the experimental immunopharmacognostic phase, immunomodulatory compounds are isolated and purified through action-guided fractionation procedures. The results described here refer to activities found on human complement activation and on PMN leucocytes activation. The immunomodulating plant compounds included in this report were isolated from Azadirachta indica bark, Woodfordia fructicosa flowers, Picrorhiza kurroa roots, and Jatropha multifida latex.
authors.forename: R P
authors.initials: RP
authors.lastname: Labadie
authors.forename: J M
authors.initials: JM
authors.lastname: van der Nat
authors.forename: J M
authors.initials: JM
authors.lastname: Simons
authors.forename: B H
authors.initials: BH
authors.lastname: Kroes
authors.forename: S
authors.initials: S
authors.lastname: Kosasi
authors.forename: A J
authors.initials: AJ
authors.lastname: van den Berg
authors.forename: L A
authors.initials: LA
authors.lastname: t' Hart
authors.forename: W G
authors.initials: WG
authors.lastname: van der Sluis
authors.forename: A
authors.initials: A
authors.lastname: Abeysekera
authors.forename: A
authors.initials: A
authors.lastname: Bamunuarachchi
mesh_terms: D000276:Adjuvants, Immunologic / Q000032:analysis*; D000818:Animals; D006801:Humans; D007166:Immunosuppressive Agents / Q000032:analysis*; D008519:Medicine, Traditional; D010600:Pharmacology; D010946:Plants, Medicinal / Q000032:analysis*
chemical_list: D000276:Adjuvants, Immunologic; D007166:Immunosuppressive Agents