title: Interstitial pneumonitis in human visceral leishmaniasis.
abstract: The involvement of the lung in 13 cases of human visceral leishmaniasis was studied. Interstitial pneumonitis with mononuclear cells was found in 76.8% of the cases; 53.8% also had foci of septal fibrosis. Leishmania were seen within macrophages in 3 cases only. However, all 10 interstitial pneumonitis cases showed PAP-positive material using specific L. donovani (MHOM/BR/72/LD 46) antiserum. 3 cases with no interstitial pneumonitis were PAP-negative. A short discussion about clinical aspects and the course of the disease is presented.
authors.affiliation: Laboratório de Patologia de Moléstias Infecciosas, Pathology Department, University of São Paulo Medical School, Brazil.
authors.forename: M I
authors.initials: MI
authors.lastname: Duarte
authors.forename: V L
authors.initials: VL
authors.lastname: da Matta
authors.forename: C E
authors.initials: CE
authors.lastname: Corbett
authors.forename: M D
authors.initials: MD
authors.lastname: Laurenti
authors.forename: R
authors.initials: R
authors.lastname: Chebabo
authors.forename: H
authors.initials: H
authors.lastname: Goto
mesh_terms: D001344:Autopsy; D006801:Humans; D007124:Immunoenzyme Techniques; D007898:Leishmaniasis, Visceral / Q000473:pathology*; D008168:Lung / Q000473:pathology*; D011658:Pulmonary Fibrosis / Q000473:pathology*