title: Is callus calcium content an indicator of the mechanical strength of healing fractures? An experimental study in rat metatarsals.
abstract: Changes in the mechanical properties and the calcium content of healing fracture callus were followed, using rat metatarsals. By 24 weeks post-fracture the mean ultimate tensile stress and elastic modulus were still less than half that of the contralateral unfractured bone, whereas the mean torsional modulus had almost reached that of the unfractured bone. The calcium content of the callus formed immediately between the fractured ends of the bone showed changes which coincided with the increases in mechanical strength and the moduli, thus measurement of callus calcium content would enable the prediction of the strength of a healing fracture.
authors.affiliation: Department of Orthopaedics, University of Sheffield, Royal Hallamshire Hospital, UK.
authors.forename: E S
authors.initials: ES
authors.lastname: Powell
authors.forename: P V
authors.initials: PV
authors.lastname: Lawford
authors.forename: T
authors.initials: T
authors.lastname: Duckworth
authors.forename: M M
authors.initials: MM
authors.lastname: Black
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000032:analysis / Q000503:physiopathology*; D002146:Bony Callus / Q000032:analysis*; D002118:Calcium / Q000032:analysis*; D050723:Fractures, Bone / Q000378:metabolism / Q000503:physiopathology*; D008297:Male; D008682:Metatarsal Bones / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013314:Stress, Mechanical; D014945:Wound Healing
chemical_list: D002118:Calcium