Transplantation in Parkinson's disease: stereotactic implantation of adrenal medulla and foetal mesencephalon.
The two possible dopamine donor sites for transplantation are autologous adrenal medulla and human foetal substantia nigra or adrenal medulla. There is increasing experience with the use of adrenal medulla transplantation for Parkinson's disease and much less experience in foetal substantia nigra transplantation. The particular problems of each technique are discussed with examples and postoperative progress of cases with the special emphasis on management problems.
Hitchcock
E R
ER
Department of Neurosurgery, University of Birmingham, Midland Centre for Neurosurgery and Neurology, U.K.
Clough
C G
CG
Hughes
R C
RC
Kenny
B G
BG
D000313:Adrenal Medulla / Q000637:transplantation*; D000328:Adult; D002421:Caudate Nucleus / Q000601:surgery*; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008636:Mesencephalon / Q000637:transplantation*; D008875:Middle Aged; D010300:Parkinson Disease / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology; D012008:Recurrence; D013238:Stereotaxic Techniques