title: Imaging the hamster flank organ by an ultrasonic technique: a new approach to animal tests.
abstract: Images of the hamster flank organ were obtained in vivo by high resolution ultrasound (B-scan). The planimetric measurements of the ultrasonic image that determined the size of the flank organ, with a reproducibility of about 10%, highly correlated with the measurements of histological sections. This new method provides a simple and non-invasive method for determining the size of the hamster flank organ after various treatments which does not involve the killing of the animal under investigation.
authors.affiliation: Laboratoire de Recherches de L'Oreal, Departement de Biophysique, Aulnay-sous-Bois, France.
authors.forename: C
authors.initials: C
authors.lastname: Combettes
authors.forename: V
authors.initials: V
authors.lastname: Durand-Seme
authors.forename: B
authors.initials: B
authors.lastname: Querleux
authors.forename: D
authors.initials: D
authors.lastname: Saint-Leger
authors.forename: J L
authors.initials: JL
authors.lastname: Leveque
mesh_terms: D000818:Animals; D006224:Cricetinae; D003534:Cyproterone / Q000494:pharmacology; D005260:Female; D005485:Flutamide / Q000494:pharmacology; D008297:Male; D008647:Mesocricetus; D009919:Orchiectomy; D012627:Sebaceous Glands / Q000033:anatomy & histology* / Q000187:drug effects; D012867:Skin / Q000033:anatomy & histology*; D013148:Spironolactone / Q000494:pharmacology; D013739:Testosterone / Q000494:pharmacology; D014463:Ultrasonography / Q000379:methods*
chemical_list: D013148:Spironolactone; D013739:Testosterone; D005485:Flutamide; D003534:Cyproterone