Jessner's lymphocytic infiltration of the skin. A clinical study of 100 patients.
Jessner's lymphocytic infiltration of the skin is a well-known but poorly understood disorder. Some doubt still exists about whether it is a single entity or a heterogeneous group that can pass into polymorphous light eruption, discoid lupus erythematosus, or even malignant lymphoma. Therefore, a large number of patients with lymphocytic infiltration of the skin (N = 100; 46 male, 54 female) were examined to elucidate these questions. We conclude that lymphocytic infiltration of the skin is a single entity. Progression into polymorphous light eruption, discoid lupus erythematosus, or lymphoma was not observed. However, this study shows that lymphocytic infiltration of the skin and polymorphous light eruption cases occur simultaneously in 1 patient. In this study the cases of 10 patients with this combination are reported. An effective but harmless therapy is yet unknown. Intermittent use of topical steroids can be useful but is not effective in many patients.
Toonstra
J
J
Department of Dermatology, University Hospital, Utrecht, the Netherlands.
Wildschut
A
A
Boer
J
J
Smeenk
G
G
Willemze
R
R
van der Putte
S C
SC
Boonstra
H
H
van Vloten
W A
WA
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000209:etiology / Q000276:immunology* / Q000473:pathology; D014466:Ultraviolet Rays / Q000009:adverse effects