title: Fetal research.
abstract: This article reviews some of the significant contributions of fetal research and fetal tissue research over the past 20 years. The benefits of fetal research include the development of vaccines, advances in prenatal diagnosis, detection of malformations, assessment of safe and effective medications, and the development of in utero surgical therapies. Fetal tissue research benefits vaccine development, assessment of risk factors and toxicity levels in drug production, development of cell lines, and provides a source of fetal cells for ongoing transplantation trials. Together, fetal research and fetal tissue research offer tremendous potential for the treatment of the fetus, neonate, and adult.
authors.affiliation: Department of Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, NY 14642.
authors.forename: J T
authors.initials: JT
authors.lastname: Hansen
authors.forename: J R
authors.initials: JR
authors.lastname: Sladek
mesh_terms: D002460:Cell Line; D000013:Congenital Abnormalities / Q000175:diagnosis; D005260:Female; D005315:Fetal Diseases; D033042:Fetal Research; D005333:Fetus / Q000166:cytology / Q000601:surgery; D030342:Genetic Diseases, Inborn; D006801:Humans; D033281:Nontherapeutic Human Experimentation; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012106:Research; D018570:Risk Assessment; D036302:Therapeutic Human Experimentation; D014612:Vaccines
chemical_list: D014612:Vaccines