[Correlation of syndrome types in traditional Chinese medicine and insulin release curves in pre-aged and aged diabetics--an analysis of 142 cases].
This paper deals with the correlation between insulin release curves and syndrome types of TCM in 142 cases of diabetes. The syndromes were divided into 3 types: I, Qi-Yin deficiency, 94 cases; II, Yin deficiency with interior heat overabundance, 36 cases; and III, deficiency of both Yin and Yang, 12 cases. The results showed that fasting for 60 min, the postprandial (M +/- SD) of serum insulin were 18.27 +/- 1.10 mu/L and 45.21 +/- 2.82 mu/L in type I 25.47 +/- 1.88 mu/L and 60.53 +/- 0.25 mu/L in Type II; 8.29 +/- 0.93 mu/L and 19.20 +/- 1.67 mu/L in type III respectively. It was obvious that serum insulin level was Type II greater than Type I greater than Type III. But there was no difference between the aged and the pre-aged with diabetes (P greater than 0.05); even though the former was lower than the latter. According to the analysis of insulin release curve types (insulin secretion level and peak time), there were 39 cases (41.5%) of the low secretion type, 7 cases (7.5%) of the high secretion type among the 94 cases of Type I. Of the 36 cases of Type II, there were 7 cases (19.4%) of high secretion, more than that of Type I, and the highest value reached 155-106 mu/L. The 12 cases of Type III are all of the lower secretion type, with the fasting mean value being 47.5 mu/L and 10.93 mu/L and the postprandial highest value 21.69 mu/L and 20.73 mu/L, much lower than those of Types I and II. The results also showed that correlation between insulin secretion level and blood glucose value was significantly negative. The paper also discussed the mechanism of insulin secretion condition of 3 syndrome types according to the theory of TCM.
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D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D003920:Diabetes Mellitus / Q000145:classification / Q000378:metabolism*; D005260:Female; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged
D001786:Blood Glucose; D007328:Insulin