Formation of highly reactive vinylglyoxylate (2-oxo-3-butenoate) from amino acids with good leaving groups in the gamma-position. Toxicological implications and therapeutic potential.
Cooper
A J
AJ
Department of Biochemistry, Cornell University Medical College, New York, NY 10021.
Hollander
M M
MM
Anders
M W
MW
D000596:Amino Acids / Q000378:metabolism* / Q000633:toxicity; D000818:Animals; D002172:Canavanine / Q000378:metabolism; D005229:Fatty Acids, Monounsaturated / Q000378:metabolism* / Q000627:therapeutic use / Q000633:toxicity; D006710:Homocysteine / Q000378:metabolism; D008717:Methionine Sulfoximine / Q000378:metabolism; D012436:S-Adenosylmethionine / Q000378:metabolism
D000596:Amino Acids; D005229:Fatty Acids, Monounsaturated; D006710:Homocysteine; D008717:Methionine Sulfoximine; D002172:Canavanine; C059218:vinylglyoxylate; D012436:S-Adenosylmethionine