A review of the role of tricyclic medications in the treatment of fibromyalgia syndrome.
The rationale behind the use of tricyclic medications in the treatment of fibromyalgia is reviewed. Controlled therapeutic trials have demonstrated significant improvement with these agents. However, important and sustained clinical improvement occurs in the minority of patients.
Goldenberg
D L
DL
Rheumatology Section, Newton-Wellesley Hospital, MA 02162.
D000639:Amitriptyline / Q000031:analogs & derivatives / Q000627:therapeutic use; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D001696:Biomechanical Phenomena; D002986:Clinical Trials as Topic; D005356:Fibromyalgia / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D010146:Pain; D010147:Pain Measurement; D012890:Sleep / Q000187:drug effects; D013577:Syndrome
D000929:Antidepressive Agents, Tricyclic; D000639:Amitriptyline; C004704:cyclobenzaprine