title: [Cimetidine treatment of stomach cancer].
abstract: The effect of cimetidine treatment in cancer of the stomach was investigated in a double-blind, multicentre study comprising eight departments in Greater Copenhagen. Immediately after operation (or the decision not to operate) 181 patients were subdivided at random to treatment with a placebo or cimetidine in a dosage of 400 mg twice daily for two years or until death. Compliance control was carried out every third month. The mean survival in the cimetidine group (450 days, 1-1,826) was significantly longer (p = 0.02) than in the placebo group (316 days, 1-1,653).
authors.forename: H
authors.initials: H
authors.lastname: Tønnesen
authors.forename: U P
authors.initials: UP
authors.lastname: Knigge
authors.forename: S
authors.initials: S
authors.lastname: Bülow
authors.forename: P
authors.initials: P
authors.lastname: Damm
authors.forename: K
authors.initials: K
authors.lastname: Fischerman
authors.forename: P
authors.initials: P
authors.lastname: Hesselfeldt
authors.forename: A
authors.initials: A
authors.lastname: Hjortrup
authors.forename: I K
authors.initials: IK
authors.lastname: Pedersen
authors.forename: V M
authors.initials: VM
authors.lastname: Pedersen
authors.forename: O J
authors.initials: OJ
authors.lastname: Siemssen
mesh_terms: D000328:Adult; D000368:Aged; D002927:Cimetidine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000401:mortality
chemical_list: D002927:Cimetidine
vernacular_title: Cimetidinbehandling ved cancer ventriculi.