[Successful treatment of autoimmune bullous diseases with a combination therapy of ciclosporin and corticosteroid].
Three patients with autoimmune bullous diseases, pemphigus vulgaris, pemphigus foliaceus and bullous pemphigoid, were treated with a combination therapy of ciclosporin and corticosteroid. These patients responded to systemic low-dose prednisolone (or dexamethasone) and low-dose ciclosporin therapy; the result was prolonged complete remission. The addition of low-dose ciclosporin may produce enhanced clinical effects of steroid therapy without increasing any significant side effects.
Kato
H
H
Murata
S
S
Suzuki
M
M
Yaoita
H
H
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001327:Autoimmune Diseases / Q000188:drug therapy* / Q000473:pathology; D003524:Cyclosporins / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage*; D012872:Skin Diseases, Vesiculobullous / Q000188:drug therapy* / Q000473:pathology
D003524:Cyclosporins; D011239:Prednisolone