title: Non-exfoliative canine cytology: the value of fine needle aspiration and scraping cytology.
abstract: The results of the cytological and histological examination of 348 canine lesions, localised in various organs, were compared with respect to the tumourous or non-tumour nature of the lesions and the malignancy or benignancy of tumours. The retrieval rate was 92.5%. Regarding the distinction between tumourous and non-tumourous lesions, the cytological examination showed a diagnostic accuracy of 83.9%, a sensitivity of 95.6%, a specificity of 65.4% and a predictive value for the presence of tumour of 93.5%. The diagnostic accuracy of cytology concerning the differentiation in malignancy and benignancy of the neoplasms was 83.7%, with a sensitivity of 86.8%, a specificity of 79.4% and a predictive value for the presence of malignant tumour of 85.6%. These results confirm the value of non-exfoliative cytology as a diagnostic method, providing rapid and valuable information with regard to diagnosis and prognosis and, consequently, for therapeutic handling. An eventual histological diagnosis remains indicated, especially in case of soft-tissue and mammary lesions.
authors.affiliation: Department of Veterinary Pathology, Faculty of Veterinary Medicine, University of Utrecht, The Netherlands.
authors.forename: J H
authors.initials: JH
authors.lastname: Vos
authors.forename: T S
authors.initials: TS
authors.lastname: van den Ingh
authors.forename: F N
authors.initials: FN
authors.lastname: van Mil
mesh_terms: D000818:Animals; D001707:Biopsy, Needle; D003584:Cytological Techniques; D003872:Dermatitis / Q000473:pathology; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D009369:Neoplasms / Q000473:pathology / Q000662:veterinary*; D013545:Sweat Glands / Q000473:pathology