[Cellular mechanisms of the development of primary arterial hypertension].
Modern views on the contraction and dilatation mechanisms of vessel smooth muscle cells are discussed. The data on main role of the cation-transport cell system function peculiarities in the primary arterial hypertension genesis, a relation cell hyperreactivity to those peculiarities and its genetical origin, are reported. It is supposed that the hereditary predisposition forms certain functional lability of cellular elements in different organism tissues, and, in consequence of that, the environmental influences can provoke the development of primary arterial hypertension.
Bershteĭn
S A
SA
Gurevich
M I
MI
D000818:Animals; D002118:Calcium / Q000502:physiology; D002462:Cell Membrane / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D009119:Muscle Contraction / Q000502:physiology*; D009131:Muscle, Smooth, Vascular / Q000502:physiology* / Q000648:ultrastructure; D051381:Rats; D011918:Rats, Inbred SHR; D012964:Sodium / Q000502:physiology; D014655:Vascular Resistance / Q000502:physiology*
D012964:Sodium; D002118:Calcium
Kletochnye mekhanizmy razvitiia pervichnoĭ arteria'lnoĭ gipertenzii.