[The role of vitamin B6 in tumor growth].
It has been demonstrated that vitamin B6 accumulated in an organism may stimulate the tumour growth as it participates in the formation of polyamines, 5,10-methylene tetrahydrofolic acid and in thymidylate synthetase conformation stabilization. Activation of the tumour growth with the vitamin B6 deficiency is shown to be induced by accumulation of blastomogenic metabolites of tryptophane. The question of vitamin B6 use in oncology remains unsolved.
Chuvykin
M B
MB
D000818:Animals; D006801:Humans; D009369:Neoplasms / Q000378:metabolism* / Q000473:pathology / Q000517:prevention & control; D011073:Polyamines / Q000378:metabolism; D011736:Pyridoxine / Q000378:metabolism* / Q000627:therapeutic use; D013763:Tetrahydrofolates / Q000378:metabolism; D013940:Thymidylate Synthase / Q000378:metabolism
D011073:Polyamines; D013763:Tetrahydrofolates; C013123:5,10-methylenetetrahydrofolic acid; D013940:Thymidylate Synthase; D011736:Pyridoxine
Rol' vitamina B6 v opukholevom roste.