title: A rapid method for the in vivo measurement of liver volume.
abstract: A method is described to calculate liver volume at US using real-time equipment. The method is based on the measurement of the 3 maximum diameters of the liver. Equations were derived by correlation vs CT volume measurement using the 3 diameters (multiple regression) or their product (simple regression) as independent variables in 20 subjects with and without liver disease. It is suggested that liver volume may be estimated as: y = -2364 + 89.2.(C-C) + 119.9.(A-P) + 59.6.(L-L) or y = 133.2 + 0.422.(C-C.A-P.L-L) where y is the volume (in ml), and C-C, A-P, and L-L are the 3 diameters (in cm). The two equations were validated in a second set of 22 subjects. US volume estimated according to Eq. 2 explained approximately 82% of the variance of the actual liver volume. The method is reproducible (interobserver variations less than 8%), rapid and easy-to-repeat. These features make it potentially useful in prospective longitudinal studies.
authors.affiliation: Istituto di Clinica Medica Generale Terapia Medica, University of Bologna, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Zoli
authors.forename: P
authors.initials: P
authors.lastname: Pisi
authors.forename: G
authors.initials: G
authors.lastname: Marchesini
authors.forename: G P
authors.initials: GP
authors.lastname: Bianchi
authors.forename: G A
authors.initials: GA
authors.lastname: Turci
authors.forename: E
authors.initials: E
authors.lastname: Pisi
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology*; D008107:Liver Diseases / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography