title: The ketoconazole-cyclosporin interaction in an elderly renal transplant patient.
abstract: Administration of ketoconazole to an elderly renal transplant patient who was taking cyclosporin resulted in markedly increased whole blood cyclosporin concentrations and evidence of both renal and hepatic dysfunction.
authors.affiliation: Department of Clinical Pharmacology, Princess Alexandra Hospital, Brisbane, Qld.
authors.forename: B G
authors.initials: BG
authors.lastname: Charles
authors.forename: P J
authors.initials: PJ
authors.lastname: Ravenscroft
authors.forename: R J
authors.initials: RJ
authors.lastname: Rigby
mesh_terms: D003524:Cyclosporins / Q000009:adverse effects / Q000493:pharmacokinetics*; D004347:Drug Interactions; D006207:Half-Life; D006801:Humans; D007654:Ketoconazole / Q000009:adverse effects* / Q000493:pharmacokinetics; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged
chemical_list: D003524:Cyclosporins; D007654:Ketoconazole