title: [Phase changes in the population of group A streptococci and their influence on the course of the epidemic process of tonsillitis].
abstract: This work presents the data on the complex evaluation of the population of group A streptococci, studied at each of four phases (reservation, epidemic transformation, epidemic spread, reservational transformation) of the course of the epidemic process of streptococcal infection of the respiratory tracts (tonsillitis) in an organized group of adults. The characterization of the phases of the infective agent in accordance with the level of the carrier state, the size of streptococcal foci and the virulence of streptococci is given. Thus, the study shows that the heterogeneity of group A streptococci with respect to their virulence reaches its maximum level at the phases of reservation and epidemic spread and its minimum level at the phases of epidemic and reservational transformation. The size of streptococcal foci in carriers and the virulence of streptococci isolated from them are the inter-related unidirectional signs of the population of the infective agent and, at the same time, the main factors responsible for the phase character of the epidemic process and the morbidity level in tonsillitis.
authors.forename: A P
authors.initials: AP
authors.lastname: Khodyrev
authors.forename: V D
authors.initials: VD
authors.lastname: Beliakov
mesh_terms: D000328:Adult; D002353:Carrier State; D006801:Humans; D013290:Streptococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000302:isolation & purification*; D014069:Tonsillitis / Q000453:epidemiology* / Q000209:etiology
vernacular_title: Fazovye izmeneniia populiatsii streptokokkov gruppy A i ikh vliianie na techenie épidemicheskogo protsessa anginy.