title: [Prostaglandins--local regulators in bone?].
abstract: Since the initial discovery by Bergström, prostaglandin E has been the focus of an intense research effort in vitro and in vivo. The regulation of bone resorption and formation involves local as well as systemic factors. In the last decade, prostaglandins have been found to be intimately associated with bone metabolism. One hypothesis consistent that osteoblastic c AMP levels play a central role in determining whether osteoblasts stimulate or inhibit osteoclastic bone resorption. The osteoinductive properties of prostaglandins were discussed.
authors.forename: T
authors.initials: T
authors.lastname: Bartels
authors.forename: W
authors.initials: W
authors.lastname: Hein
authors.forename: C
authors.initials: C
authors.lastname: Taube
authors.forename: H J
authors.initials: HJ
authors.lastname: Mest
mesh_terms: D000818:Animals; D001861:Bone Regeneration; D001862:Bone Resorption / Q000503:physiopathology*; D006801:Humans; D010006:Osteoblasts / Q000502:physiology; D010010:Osteoclasts / Q000502:physiology; D011453:Prostaglandins / Q000502:physiology*
chemical_list: D011453:Prostaglandins
vernacular_title: Prostaglandine--lokale Mediatoren im Knochen?