title: [Biological effects of interleukin-2 and prospects for its use in the immunotherapy of malignant neoplasms].
abstract: The data on biological properties and effects of interleukin-2, one of the main mediators of the immunity are presented. The results of its use in the tumour immunotherapy are analyzed, the used approaches and mechanisms of action of this kind of immunotherapy being estimated. The ways to increase the efficiency of interleukin-2 application in clinics are under discussion.
authors.forename: N M
authors.initials: NM
authors.lastname: Berezhnaia
authors.forename: B A
authors.initials: BA
authors.lastname: Goretskiĭ
mesh_terms: D000818:Animals; D006801:Humans; D007376:Interleukin-2 / Q000494:pharmacology* / Q000627:therapeutic use; D008214:Lymphocytes / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D009369:Neoplasms / Q000276:immunology / Q000628:therapy*; D012509:Sarcoma / Q000276:immunology / Q000628:therapy; D012983:Soft Tissue Neoplasms / Q000276:immunology / Q000628:therapy
chemical_list: D007376:Interleukin-2
vernacular_title: Biologicheskie éffekty interleĭkina-2 i perspektivy ego ispol'zovaniia v immunoterapii zlokachestvennykh novoobrazovaniĭ.