Use of a trypsin, Peru balsam, and castor oil spray on the oral mucosa: case report and review of the literature.
Granulex is an aerosolized spray (Dow B. Hickman Pharmaceuticals, Sugar Land, TX 77487) that contains trypsin, Peru balsam, and castor oil. It has been available for many years as a topical spray for the treatment of decubitus ulcers. We used Granulex to promote tissue healing of a necrotic ulcer of the oral mucosa in a patient with advanced oropharyngeal squamous cell carcinoma.
Noble
T A
TA
Department of Pharmacy Practice, College of Pharmacy, University of South Carolina, Columbia 29208.
Carr
D S
DS
Gonzalez
M F
MF
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001453:Balsams / Q000008:administration & dosage / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D002368:Castor Oil / Q000008:administration & dosage / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D003561:Cytarabine / Q000008:administration & dosage; D004338:Drug Combinations / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006918:Hydroxyurea / Q000008:administration & dosage; D009061:Mouth Mucosa; D009062:Mouth Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D009910:Oral Hygiene; D014357:Trypsin / Q000008:administration & dosage / Q000627:therapeutic use*; D014945:Wound Healing / Q000187:drug effects*
D001453:Balsams; D004338:Drug Combinations; C062801:Granulex; D003561:Cytarabine; D002368:Castor Oil; D014357:Trypsin; D002945:Cisplatin; D006918:Hydroxyurea