The pathophysiological role of PAF in anaphylactic lung reaction in the guinea pig and in endotoxin shock evidenced by the specific PAF-antagonist WEB 2086.
Heuer
H
H
Department of Pharmacology, Boehringer Ingelheim, FRG.
Casals-Stenzel
J
J
D000707:Anaphylaxis / Q000209:etiology* / Q000517:prevention & control; D000818:Animals; D000941:Antigens; D001381:Azepines / Q000008:administration & dosage / Q000627:therapeutic use*; D004195:Disease Models, Animal; D004731:Endotoxins; D004926:Escherichia coli; D006168:Guinea Pigs; D008171:Lung Diseases / Q000209:etiology* / Q000517:prevention & control; D010047:Ovalbumin; D010972:Platelet Activating Factor / Q000037:antagonists & inhibitors / Q000502:physiology*; D011738:Pyrilamine / Q000627:therapeutic use; D012772:Shock, Septic / Q000209:etiology* / Q000517:prevention & control; D014227:Triazines / Q000008:administration & dosage / Q000627:therapeutic use*; D014230:Triazoles
D000941:Antigens; D001381:Azepines; D004731:Endotoxins; D010972:Platelet Activating Factor; D014227:Triazines; D014230:Triazoles; C052518:WEB 2086; D010047:Ovalbumin; D011738:Pyrilamine