title: Abnormally high values of CA 125 and CA 19-9 in women with benign tumors.
abstract: Tumor markers have proved to be generally useful for diagnosing and monitoring malignancy. In contrast, high levels of tumor markers disturb us for differing benign disease from malignancy. We had 5 cases with benign disease who showed high values of tumor markers (CA 125 and CA 19-9). In this report, we illustrated 3 patients with endometriosis who showed high values of CA 125 and 2 patients with dermoid cyst who showed high values of CA 19-9. It was impossible to rule out malignant disease in all cases preoperatively. In diagnosing ovarian tumors, bimanual examination, ultrasound, CT scan and tumor markers should all be considered.
authors.affiliation: Department of Obstetrics and Gynecology, Shimane Medical University, Izumo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Nagata
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
authors.forename: Y
authors.initials: Y
authors.lastname: Yamane
authors.forename: K
authors.initials: K
authors.lastname: Yoshino
authors.forename: T
authors.initials: T
authors.lastname: Shibukawa
authors.forename: M
authors.initials: M
authors.lastname: Kitao
mesh_terms: D000328:Adult; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis*; D014408:Biomarkers, Tumor / Q000097:blood*; D003884:Dermoid Cyst / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004715:Endometriosis / Q000175:diagnosis*; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008875:Middle Aged; D010048:Ovarian Cysts / Q000175:diagnosis*; D010051:Ovarian Neoplasms / Q000175:diagnosis*; D014463:Ultrasonography
chemical_list: D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor