[Molecular mechanisms of protective reactions of the body: time scale, specificity scale].
Heterogeneous conformation transition (HCT) peculiar to proteins is the earliest protection of the organism from poisons, toxins and pathological metabolites, HCT is conjugated with the biosynthesis of heat shock proteins (HSP), glycosylation of modified albumin and with an increase in the biosynthesis of soluble lectins, acute phase reactants (APR). All phases except for HCT are regulated at different levels of the protein biosynthesis. Their individual time corresponds to the evolution stages.
Troitskiĭ
G V
GV
D000595:Amino Acid Sequence; D000818:Animals; D001798:Blood Proteins / Q000378:metabolism; D006360:Heat-Shock Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism; D006801:Humans; D008969:Molecular Sequence Data; D011041:Poisoning / Q000517:prevention & control*; D011487:Protein Conformation; D013997:Time Factors
D001798:Blood Proteins; D006360:Heat-Shock Proteins
Molekuliarnye mekhanizmy zashchitnykh reaktsiĭ organizma: shkala vremeni, shkala spetsifichnosti.