Enoxacin in the therapy of anal and pharyngeal gonococcal infections.
In this randomized double-blind study, 51 patients with uncomplicated anal or pharyngeal Neisseria gonorrhoeae infection were evaluated to determine the efficacy and safety of 200- or 400-mg of enoxacin twice a day for two days. Enoxacin cured all anal infections and 12 out of 13 pharyngeal infections. All 82 isolates of N. gonorrhoeae tested were inhibited by 1 microgram of enoxacin/ml.
Romanowski
B
B
Sexually Transmitted Disease Clinic, Edmonton, Alberta, Canada.
Hardy
J S
JS
Rafter
M S
MS
Draker
J
J
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D015365:Enoxacin / Q000008:administration & dosage*; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy*; D006801:Humans; D008297:Male; D010612:Pharyngitis / Q000188:drug therapy*; D011349:Proctitis / Q000188:drug therapy*; D016032:Randomized Controlled Trials as Topic
D015365:Enoxacin