title: [The differential diagnosis of chronic pancreatitis and pancreatic cancer].
abstract: The following examinations were carried out in patients with chronic pancreatitis and pancreatic cancer: pancreozymin-secretin test, sonography, computed axial tomography, endoscopic retrograde cholangiopancreatography (ERCP) and thin-needle aspiration pancreatic biopsy. In 93.4% of the patients with chronic pancreatitis and in 93.8% of the patients with pancreatic cancer statistically significant changes in the pancreatic exocrine secretion were found after pancreozymin-secretin stimulation. Changes in the pancreatic function cannot be used as a reliable criterion for the differential diagnosis between chronic pancreatitis and pancreatic cancer. The ultrasound examination ensured correct diagnosis in 79% of the patients with chronic pancreatitis and in 76.4% of the patients with pancreatic cancer while the computed tomography gave the correct diagnosis in 80% and 79.4% of the patients respectively. The endoscopic retrograde pancreatography enabled correct diagnosis in 90% of the patients with chronic pancreatitis and in 86.2% of the patients with pancreatic cancer. The thin-needle biopsy revealed malignant cells in 97.5% of the patients with pancreatic cancer. The differential diagnosis between chronic pancreatitis and pancreatic cancer was not decided in 16.2% of the patients examined by sonography, 12% of the patients examined by computed tomography, 7.4% of the patients examined by ERCP and in only 2.5% of the patients examined cytologically.
authors.forename: Kh
authors.initials: Kh
authors.lastname: Brailski
authors.forename: A
authors.initials: A
authors.lastname: Mendizova
authors.forename: L
authors.initials: L
authors.lastname: Dinkov
authors.forename: D
authors.initials: D
authors.lastname: Damianov
authors.forename: I
authors.initials: I
authors.lastname: Glavincheva
mesh_terms: D001707:Biopsy, Needle; D002760:Cholangiopancreatography, Endoscopic Retrograde; D002908:Chronic Disease; D003937:Diagnosis, Differential; D006801:Humans; D010179:Pancreas / Q000000981:diagnostic imaging / Q000473:pathology; D010186:Pancreatic Function Tests; D010190:Pancreatic Neoplasms / Q000175:diagnosis*; D010195:Pancreatitis / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
vernacular_title: Vŭrkhu diferentsialnata diagnoza na khronichniia pankreatit i raka na pankreasa.