[Evaluation of the efficacy and tolerability of a fixed dose combination of captopril (CPT) 50 mg and hydrochlorothiazide (HCTZ) 15 mg in the elderly].
In this double blind study we have evaluated the efficacy and tolerability of the association Captopril 50 mg + hydrochlorothiazide 15 mg/die vs hydrochlorothiazide 25 mg/die in aged patients with hypertension. Both drugs showed a good antihypertensive efficacy, and a better efficacy on diastolic blood pressure was shown by the association Captopril + hydrochlorothiazide.
Antonicelli
R
R
Raffaelli
S
S
Bossini
A
A
Paciaroni
E
E
Zingaretti
P
P
Botta
G F
GF
D000368:Aged; D000369:Aged, 80 and over; D002216:Captopril / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D016032:Randomized Controlled Trials as Topic
D006852:Hydrochlorothiazide; D002216:Captopril
Valutazione dell'efficacia e tollerabilità dell'associazione a dose fissa di captopril (CPT) 50 mg e idroclorotiazide (HCTZ) 15 mg in soggetti anziani.