The clinical effect of felodipine and nifedipine in Raynaud's phenomenon.
Sixteen patients participated in a double-blind cross-over trial comparing the effect of two dosages of the new calcium entry blocker, felodipine, with nifedipine in the treatment of Raynaud's phenomenon. The effect was evaluated using a symptom recording system. As no difference was found between the 3 treatments, the lower dose of felodipine (10 mg) may be preferable as only one dose per day is necessary.
Schmidt
J F
JF
Department of Anesthesiology, Gentofte Hospital, Denmark.
Valentin
N
N
Nielsen
S L
SL
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004311:Double-Blind Method; D015736:Felodipine / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009543:Nifedipine / Q000009:adverse effects / Q000627:therapeutic use*; D016032:Randomized Controlled Trials as Topic; D011928:Raynaud Disease / Q000188:drug therapy*
D009543:Nifedipine; D015736:Felodipine