[The significance of detecting sex hormone receptors for the treatment and prognostic assessment of malignant melanoma].
The current seek for alternative or supplemented therapy is a corner stone in controlled clinical trials and researches concerning malignant melanoma. The discovery of intracytoplasmatic estrogen receptors in the cells of malignant melanoma raised the hope for the use of sexual hormones to perform this therapeutic aspect. In this paper we report on the nature of these sexual hormone receptors, new methodical possibilities, correlations to clinical data together with their significance in diagnosis, therapy and prognosis of malignant melanoma.
Wehner
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F
Wohlrab
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W
D001706:Biopsy; D006801:Humans; D008545:Melanoma / Q000473:pathology*; D009376:Neoplasms, Hormone-Dependent / Q000473:pathology*; D011379:Prognosis; D011960:Receptors, Estrogen / Q000032:analysis*; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*
D011960:Receptors, Estrogen
Die Bedeutung des Nachweises von Sexualhormonrezeptoren für die Therapie und Prognosefindung maligner Melanome.