title: [Changes in the rat endocrine pancreas under the effect of urbazon].
abstract: Hypertrophy and hyperplasia of islet tissue, established by morphometry, were proved in the pancreas of rats, treated chronically for a period of 2 months (with urbason-50 mg/kg of body mass). B-cells were granulated. Structures with myelin-like form of membranes were observed in some of them by electron microscope. Mixed islet B-acinar cells were established as well. These data were possibly a morphological expression of stimulating action of urbason on B-cells of Langerhans islets.
authors.forename: M
authors.initials: M
authors.lastname: Zafirova
authors.forename: R
authors.initials: R
authors.lastname: Zhablenska
authors.forename: Ts
authors.initials: Ts
authors.lastname: Mikhova
authors.forename: P
authors.initials: P
authors.lastname: Petkov
authors.forename: D
authors.initials: D
authors.lastname: Dochev
mesh_terms: D000818:Animals; D006965:Hyperplasia; D006984:Hypertrophy; D007515:Islets of Langerhans / Q000187:drug effects* / Q000473:pathology; D008297:Male; D008775:Methylprednisolone / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D008775:Methylprednisolone
vernacular_title: Promeni v endokrinniia pankreas na plŭkh pod vŭzdeĭstvieto na urbazon.