The porphyrias.
The importance of recognizing these rare metabolic disorders in the Emergency Department patient is discussed. The pathophysiologic mechanisms behind the neurologic and cutaneous manifestations of these disorders is reviewed; presentation and management of the acute hepatic porphyrias are described; and features of the erythropoietic porphyrias and porphyria cutanea tarda are presented.
Werman
H A
HA
Division of Emergency Medicine, Ohio State University School of Medicine, Columbus.
D000208:Acute Disease; D004920:Erythropoiesis; D006418:Heme / Q000096:biosynthesis; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D011164:Porphyrias / Q000175:diagnosis / Q000378:metabolism / Q000503:physiopathology; D012871:Skin Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy
D006418:Heme