[Drug-induced bone pathology].
Some drugs are potentially toxic, directly or indirectly, to bone tissue. However, the banality of the bone pathology renders a definitive association difficult. Osteomalacia can be triggered by anticonvulsants, aluminum, fluoride or diphosphonates. Osteoporosis is induced more commonly with corticosteroids, long-term heparin administration or hypothyroid hormonal replacement therapy. The link between the bone disease and the suspected drug is accepted only if there is no other risk factor and after histomorphometric confirmation of the bone pathology.
Schiano
A
A
Service de Neurologie et des Maladies de l'Appareil Locometeur, CHU de la Timone, Marseille.
Chouc
P Y
PY
Desnuelle
C
C
Serratrice
G
G
D000305:Adrenal Cortex Hormones / Q000009:adverse effects; D001847:Bone Diseases / Q000139:chemically induced*; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D010018:Osteomalacia / Q000139:chemically induced; D010024:Osteoporosis / Q000139:chemically induced
D000305:Adrenal Cortex Hormones
La pathologie osseuse d'origine médicamenteuse.