[Cutaneous angiitis: direct immunofluorescence and morphopathology in 23 cases].
We reviewed the findings in 23 patients with histologically diagnosed cutaneous angiitis, between 1981 and 1985. There were 8 males and 15 females, with a mean age of 43 years. Four histological patterns were identified: leukocytoclastic angeitis in 9 (31%), lymphocytic angeitis in 8 (35%), capillaritis in 2 (9%) and minimal alterative angeitis in 4 (17%). Serum complement levels were normal in 56% and low in the remainder. Fourteen patients (61%) showed positive direct immunofluorescence for complement fractions and different immunoglobulins in skin lesions. All cases with lymphocytic angeitis yielded a positive reaction as compared to only 66% in leucocytoclastic angeitis. No correlation was found between serum complement levels and histologic pattern of angeitis. The present results suggest that direct immunofluorescence in diseased skin is a more sensitive procedure for identifying active cutaneous angeitis.
Chuaqui
R
R
González
S
S
D000293:Adolescent; D000328:Adult; D000368:Aged; D000888:Antibodies, Anti-Idiotypic / Q000032:analysis; D003165:Complement System Proteins / Q000032:analysis; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012871:Skin Diseases / Q000473:pathology*; D014657:Vasculitis / Q000473:pathology*
D000888:Antibodies, Anti-Idiotypic; D003165:Complement System Proteins
Angeítis cutáneas: inmunofluorescencia directa y morfopatología de 23 casos.