Haemophagocytic syndrome complicating acute lymphoblastic leukaemia.
A 41 year old female developed reactive haemophagocytic histiocytosis secondary to herpes simplex infection, during remission induction for acute lymphoblastic leukaemia. She recovered fully with acyclovir and supportive treatment. Previous publications on the association between acute lymphoblastic leukaemia and haemophagocytic syndrome are reviewed, and the nature of the haemophagocytic disorder is discussed.
Stark
R
R
Department of Clinical Haematology, St George Hospital, University of New South Wales, Sydney, Australia.
Manoharan
A
A
D000212:Acyclovir / Q000627:therapeutic use; D000328:Adult; D005260:Female; D006561:Herpes Simplex / Q000150:complications*; D054747:Histiocytic Sarcoma / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D009894:Opportunistic Infections / Q000150:complications*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D012074:Remission Induction
D000212:Acyclovir