title: Humoral circulatory immune response to Gardnerella vaginalis.
abstract: Strain-specific circulating immunoglobulin G and/or M was detected by enzyme-linked immunosorbent assay and immunofluorescence test by using Formol-treated suspensions of Gardnerella vaginalis from 28 women with overt vaginitis but only three symptom-free subjects among 43 otherwise healthy women found to be colonized by G. vaginalis. Analogous but less stringent strain specificity patterns were elicited by immunization of BALB/c mice.
authors.affiliation: Institute of Medical Microbiology, University of Milan, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Ghione
authors.forename: P A
authors.initials: PA
authors.lastname: Clerici
authors.forename: G
authors.initials: G
authors.lastname: Piragine
authors.forename: E
authors.initials: E
authors.lastname: Magliano
mesh_terms: D000328:Adult; D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis*; D000918:Antibody Specificity; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005455:Fluorescent Antibody Technique; D006194:Gardnerella vaginalis / Q000276:immunology*; D006190:Haemophilus / Q000276:immunology*; D006192:Haemophilus Infections / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis; D007075:Immunoglobulin M / Q000096:biosynthesis; D051379:Mice; D008807:Mice, Inbred BALB C; D014627:Vaginitis / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial; D007074:Immunoglobulin G; D007075:Immunoglobulin M