title: A comparison of freeze-dried bone allograft and demineralized freeze-dried bone allograft in human periodontal osseous defects.
abstract: This study was conducted to clinically compare freeze-dried bone allograft (FDBA) and demineralized freeze-dried bone allograft (DFDBA). Twenty-two defects (11 intrapatient pairs) in 9 patients were grafted with either DFDBA or FDBA. Evaluations were based on standardized radiographs, presurgical and postsurgical soft tissue measurements using the cemento-enamel junction as a fixed reference point, and osseous measurements at the time of surgery. Grafted sites were re-entered at a minimum of 6 months following placement. A mean osseous repair of 1.7 mm (59%) occurred with DFDBA and 2.4 mm (66%) with FDBA. A mean clinical attachment gain of 1.7 mm was obtained with DFDBA and 2.0 mm with FDBA. Probing depths decreased a mean of 2.00 mm with both DFDBA and FDBA. These findings reveal no significant differences between the two materials in primarily intraosseous defects when evaluated at a minimum 6 months postsurgery.
authors.affiliation: Naval Dental Clinic, San Diego, CA.
authors.forename: J M
authors.initials: JM
authors.lastname: Rummelhart
authors.forename: J T
authors.initials: JT
authors.lastname: Mellonig
authors.forename: J L
authors.initials: JL
authors.lastname: Gray
authors.forename: H J
authors.initials: HJ
authors.lastname: Towle
mesh_terms: D000328:Adult; D000539:Alveolar Process / Q000601:surgery; D001861:Bone Regeneration; D001862:Bone Resorption / Q000601:surgery*; D016025:Bone Transplantation / Q000379:methods*; D003648:Decalcification Technique; D005260:Female; D005612:Freeze Drying; D006801:Humans; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000601:surgery*; D014945:Wound Healing