Prolonged ventricular support using a centrifugal pump.
The Biomedicus centrifugal pump was required to provide prolonged ventricular support to 13 patients with hemodynamic instability: 11 after cardiovascular surgical procedures, 1 after myocardial infarction and 1 after failure of a heart transplant. The duration of support ranged from 3.5 hours to 9 days (mean 72 hours). Complications included bleeding in six patients, renal insufficiency in three and central nervous system deficit in three. Six patients (46%) were successfully weaned from the pump. The patient with graft failure had hyperacute rejection of a second heart. Five patients were discharged from the hospital. There was one death 8 months postoperatively. Prolonged ventricular support with the centrifugal pump may allow recovery of potentially reversible ventricular dysfunction in selected patients after cardiac surgical procedures.
Hoy
F B
FB
University of Illinois College of Medicine, Peoria.
Stables
C
C
Gomez
R C
RC
Munns
J R
JR
Geiss
D M
DM
Flack
D
D
Filko
D
D
Zischler
J
J
Schmidt
D
D
D000293:Adolescent; D000328:Adult; D001243:Assisted Circulation / Q000009:adverse effects; D006348:Cardiac Surgical Procedures; D002648:Child; D002675:Child, Preschool; D016027:Heart Transplantation; D006353:Heart-Assist Devices / Q000009:adverse effects; D006801:Humans; D007223:Infant; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications; D011183:Postoperative Complications / Q000628:therapy*; D012770:Shock, Cardiogenic / Q000209:etiology / Q000628:therapy*; D013318:Stroke Volume; D013997:Time Factors