Trace element profiles in oesophageal neoplasms determined by proton-induced X-ray emission.
Trace element concentrations were determined in surgically resected, cancerous human oesophageal tissue by proton-induced X-ray emission (PIXE) analysis. Each sample was divided into six zones, E3 and E4 formed the central tumour region, E1 and E2 were proximal to the oesophagus and E5 and E6 distal to the oesophagus. Malignancy was confirmed histopathologically in all cases. Samples were dissolved in NaOH solution and pipetted onto a thin mylar film for analysis by a proton beam from a Van de Graaff accelerator. Titanium, Fe, Cu, Zn, As, Rb, Br and Pb were detected in varying concentrations. Of these, Ti, Fe, Cu, Zn and As showed specific behaviour in the six zones.
Lal
M
M
Nuclear Physics Division, Bhabha Atomic Research Centre, Bombay, India.
Choudhury
R K
RK
Nayak
B K
BK
Bamane
V S
VS
Trivedi
P N
PN
Ranade
S S
SS
D002277:Carcinoma / Q000032:analysis / Q000601:surgery; D004938:Esophageal Neoplasms / Q000032:analysis* / Q000601:surgery; D006801:Humans; D013052:Spectrometry, X-Ray Emission / Q000379:methods; D014131:Trace Elements / Q000032:analysis*
D014131:Trace Elements