title: [Post-traumatic pulmonary insufficiency: therapeutic measures].
abstract: The pathophysiology of posttraumatic pulmonary failure is today reasonably well known. Interaction of altered granulocytes with the pulmonary parenchyma in the form of an inflammatory reaction plays an important role. Gas exchange failure can be a major problem in these patients and influence the prognosis. No effective preventive treatment is known at present except for rapid and appropriate surgical management together with an adequate fluid resuscitation. In addition, the risk of infection and sepsis must be reduced as far as possible and dysfunction of other organ systems prevented if the prognosis is to be improved. Administration of anti-inflammatory agents and corticosteroids has been shown to be without beneficial effect and dangerous in this situation. Intubation and ventilatory assistance should be used depending on respiratory status and pulmonary gas exchange, although potentially lifethreatening side effects of this treatment must be considered. Continuous specific monitoring of respiratory function must be started in the patient after multiple trauma to follow the course of pulmonary dysfunction and adapt therapy.
authors.affiliation: Département d'anesthésiologie, Hôpital cantonal universitaire de Genève.
authors.forename: P M
authors.initials: PM
authors.lastname: Suter
authors.forename: D R
authors.initials: DR
authors.lastname: Morel
authors.forename: M C
authors.initials: MC
authors.lastname: Laverrière
mesh_terms: D006098:Granulocytes / Q000503:physiopathology; D006801:Humans; D007440:Intubation; D012121:Respiration, Artificial / Q000379:methods; D012128:Respiratory Distress Syndrome / Q000503:physiopathology*; D012769:Shock / Q000503:physiopathology / Q000628:therapy; D014882:Water-Electrolyte Balance; D014947:Wounds and Injuries / Q000503:physiopathology* / Q000628:therapy
vernacular_title: Insuffisance pulmonaire post-traumatique: moyens thérapeutiques.