[Laboratory and oligobiopsy studies of the liver in patients with psoriasis treated by the combination of Tigason-PUVA-cignoline (RePUVA+C)].
In 10 patients with generalized psoriasis treated by this method biochemical and histological examinations of liver biopsy specimens were done before and after 60 days of the treatment. In some cases a transient rise of A1AT activity, raised activity of alkaline phosphatase and gamma-glutamyltranspeptidase were noted. Histological examinations demonstrated slight hepatocellular damage with microfocal necrosis, fatty infiltration of some cells and increase in the structural elements of cytoplasm.
Ruszczak
Z
Z
Biernat
S
S
Prószyńska-Kuczyńska
W
W
Drobnik
G
G
Drobnik
S
S
D000328:Adult; D000875:Anthralin / Q000008:administration & dosage*; D001706:Biopsy / Q000379:methods; D002986:Clinical Trials as Topic; D005050:Etretinate / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008099:Liver / Q000187:drug effects / Q000473:pathology* / Q000503:physiopathology; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D011701:PUVA Therapy; D011565:Psoriasis / Q000188:drug therapy / Q000473:pathology* / Q000503:physiopathology
D005050:Etretinate; D000875:Anthralin
Laboratoryjne i oligobiopsyjne badania watroby u chorych na łuszczyce leczonych metoda skojarzona Tigason-PUVA-cignolina (RePUVA+C).