title: 5-Aminosalicylic acid suppositories in the management of ulcerative colitis.
abstract: 5-aminosalicylic acid (5-ASA) suppositories have been used in the author's out-patient clinic in Bologna for the treatment of distal ulcerative colitis (UC). One hundred fifty-six patients with mild or moderate attacks of UC were treated using different protocols for controlling active disease. Improvement was observed in 88.5 percent of the therapeutic cycles after one month. A small preliminary maintenance study using only 400-mg suppositories of 5-ASA twice a day for 6 or 12 months showed a remission percentage similar to salicylazosulfapyridine (SASP).
authors.affiliation: Instituto Clinica Medica e Gastroenterologia, Universita di Bologna, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Campieri
authors.forename: P
authors.initials: P
authors.lastname: Gionchetti
authors.forename: A
authors.initials: A
authors.lastname: Belluzzi
authors.forename: C
authors.initials: C
authors.lastname: Brignola
authors.forename: F
authors.initials: F
authors.lastname: Torresan
authors.forename: M
authors.initials: M
authors.lastname: Tampieri
authors.forename: P
authors.initials: P
authors.lastname: Iannone
authors.forename: M
authors.initials: M
authors.lastname: Miglioli
authors.forename: L
authors.initials: L
authors.lastname: Barbara
mesh_terms: D000328:Adult; D000636:Aminosalicylic Acids / Q000008:administration & dosage*; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D019804:Mesalamine; D008875:Middle Aged; D012810:Sigmoid Diseases / Q000188:drug therapy; D013488:Suppositories
chemical_list: D000636:Aminosalicylic Acids; D013488:Suppositories; D019804:Mesalamine