title: Alterations in bovine lymphocyte function during the periparturient period.
abstract: Lymphocytes from 8 Holstein heifers were evaluated during the periparturient period for mitogen-induced lymphocyte blastogenic responses. Phytohemagglutinin P- and concanavalin A-induced lymphocyte blastogenesis increased 2 and 3 weeks before parturition, respectively. However, by the first week after parturition, lymphocyte blastogenesis was markedly impaired.
authors.affiliation: USDA, National Animal Disease Center, Ames, IA 50010.
authors.forename: M E
authors.initials: ME
authors.lastname: Kehrli
authors.forename: B J
authors.initials: BJ
authors.lastname: Nonnecke
authors.forename: J A
authors.initials: JA
authors.lastname: Roth
mesh_terms: D000818:Animals; D002417:Cattle; D003208:Concanavalin A / Q000494:pharmacology; D005260:Female; D007743:Labor, Obstetric / Q000276:immunology*; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008892:Milk / Q000032:analysis; D010835:Phytohemagglutinins / Q000494:pharmacology; D011043:Pokeweed Mitogens / Q000494:pharmacology; D049590:Postpartum Period / Q000276:immunology*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000276:immunology*; D013997:Time Factors
chemical_list: D010835:Phytohemagglutinins; D011043:Pokeweed Mitogens; D003208:Concanavalin A