Ciprofloxacin for methicillin-resistant Staphylococcus aureus infections.
Thirty-seven patients with methicillin-resistant Staphylococcus aureus infections and/or colonization were treated with oral ciprofloxacin (750 mg twice a day). Clinical cure or improvement of infections occurred in 91% of the patients, and bacteriologic cure occurred in 60%. Ciprofloxacin therapy suppressed methicillin-resistant S. aureus colonization in 55% of the patients. Ciprofloxacin-resistant strains emerged in 6 of the 37 patients.
Piercy
E A
EA
Division of Infectious Diseases, University of Texas Southwestern Medical Center, Dallas 75235.
Barbaro
D
D
Luby
J P
JP
Mackowiak
P A
PA
D002939:Ciprofloxacin / Q000627:therapeutic use*; D004352:Drug Resistance, Microbial; D006801:Humans; D008712:Methicillin / Q000494:pharmacology; D010403:Penicillin Resistance; D013203:Staphylococcal Infections / Q000188:drug therapy*; D013211:Staphylococcus aureus / Q000187:drug effects
D002939:Ciprofloxacin; D008712:Methicillin