title: [Treatment of status asthmaticus. Experience of intravenous beta-adrenergic bronchodilator therapy in 71 cases].
abstract: A retrospective study of the patients admitted during the last 8 years with status asthmaticus is reported. We compare the requirement of mechanical ventilation with the beta-agonist therapy received and the type of asthma. About 71 patients admitted, 67% were IgE dependent asthmatic (EDA) children and 31% no-IgE dependent asthmatic (nEDA) ones. They needed intermittent positive pressure ventilation (IPPV) in 20 instances; no difference was found between both types of asthma. We studied the ventilatory parameters used. The 33% of EDA children was treated using a continuous IV infusion of hexoprenalina, requiring IPPV in 5 (31%) of them. The rest received a continuous IV of isoproterenol, and only the 16% required IPPV. We found isoproterenol to be more effective than hexoprenalina in the treatment of status asthmaticus. Similar results were obtained with the nEDA group. The Downes score was showed to be a good predictor-index scoring system in many cases.
authors.affiliation: Hospital Infantil Valle del Hebrón, Barcelona.
authors.forename: J
authors.initials: J
authors.lastname: Escribano Subias
authors.forename: N
authors.initials: N
authors.lastname: Sanz Manrique
authors.forename: V
authors.initials: V
authors.lastname: Morales Hidalgo
authors.forename: R
authors.initials: R
authors.lastname: Clofent Vilaplana
authors.forename: J
authors.initials: J
authors.lastname: Iglesias Berenguer
authors.forename: J
authors.initials: J
authors.lastname: Roqueta Mas
authors.forename: J L
authors.initials: JL
authors.lastname: Eseverri Asin
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000188:drug therapy*; D001993:Bronchodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004341:Drug Evaluation; D005260:Female; D006594:Hexoprenaline / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007275:Injections, Intravenous; D007385:Intermittent Positive-Pressure Ventilation; D007545:Isoproterenol / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D012189:Retrospective Studies; D013224:Status Asthmaticus / Q000188:drug therapy* / Q000628:therapy
chemical_list: D001993:Bronchodilator Agents; D006594:Hexoprenaline; D007545:Isoproterenol
vernacular_title: Tratamiento del estado asmático. Experiencia del tratamiento broncodilatador beta-adrenérgico EV sobre 71 casos.