[Neurophysiological study of autistic children].
Two different hypotheses have been proposed on the pathophysiology of infantile autism; a caudally directed pathological influence originating in telencephalic structure, and a rostrally directed pathological influence originating in brainstem and diencephalic structure. This paper described results of neurophysiologic research of infantile autism: (1) cortical evoked potentials, (2) autoregressive spectral analysis of EEG, (3) brainstem lesions on ABR and vestibular study by Ornitz E M (1985) and (4) cognitive functioning by Novick (1980) and Niwa (1983). Those studies suggest that the brainstem, including the vestibular nuclei, and related nonspecific thalamic centers, can be the primary loci of the system dysfunction in autism.
Ogawa
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D001321:Autistic Disorder / Q000503:physiopathology*; D001921:Brain / Q000503:physiopathology*; D001933:Brain Stem / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D008297:Male; D013788:Thalamus / Q000503:physiopathology