A t(3;5) in blastic phase of a Philadelphia chromosome-negative chronic myeloid leukemia.
Serial cytogenetic analyses from the bone marrow of a patient with blastic phase of a Philadelphia chromosome-negative chronic myeloid leukemia revealed a t(3;5)(p21;q31). The literature on translocations involving chromosome 3 and the long arm of chromosome 5 is reviewed. The importance of breakpoints in band 5q31 is discussed.
De Braekeleer
M
M
Department of Human Sciences, University of Quebec, Chicoutimi, Canada.
Vekemans
M
M
D000293:Adolescent; D002893:Chromosomes, Human, Pair 3; D002895:Chromosomes, Human, Pair 5; D006133:Growth Substances / Q000235:genetics; D006410:Hematopoiesis; D006801:Humans; D054438:Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic
D006133:Growth Substances