title: Chemotherapy as the initial treatment of spinal cord compression due to disseminated neuroblastoma.
abstract: During a 12-month trial period, all children attending the Hospitals for Sick Children, London, England, for management of spinal cord compression due to disseminated neuroblastoma were given chemotherapy as initial treatment rather than radiotherapy or laminectomy. Response to treatment was evaluated by a neurosurgeon as well as by oncologists. Four children were treated in this way and all made a full recovery of spinal cord function.
authors.affiliation: Department of Haematology, Hospital for Sick Children, London, England.
authors.forename: I R
authors.initials: IR
authors.lastname: Sanderson
authors.forename: J
authors.initials: J
authors.lastname: Pritchard
authors.forename: H T
authors.initials: HT
authors.lastname: Marsh
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009364:Neoplasm Recurrence, Local; D009447:Neuroblastoma / Q000150:complications* / Q000188:drug therapy; D013116:Spinal Cord / Q000503:physiopathology; D013117:Spinal Cord Compression / Q000209:etiology* / Q000503:physiopathology; D013120:Spinal Cord Neoplasms / Q000150:complications* / Q000188:drug therapy
chemical_list: D000970:Antineoplastic Agents