Successful transplantation of a free fimbrial graft to the peritoneum.
Loss of fertility due to prior segmental resection of the fallopian tube (for ectopic pregnancy or sterilization) can be treated with a free fimbrial graft, especially when the fimbrial segment is contralateral to the proximal tube that is needed for the anastomosis. To evaluate the structure and function of the fimbria after free grafting, the fimbria was cut from the tube and sewn without a blood supply to the peritoneum in 14 rabbits. After convalescence, scanning electron microscopy showed fewer secondary mucosal folds in the grafted fimbria than in the normal fimbria. The ciliated and secretory cells in the graft were identical to those of normal cells. The transport rate of surrogate ova across the grafted fimbrial mucosa was consistent with that across the normal fimbrial mucosa, demonstrating that near-normal structure and function are preserved after a free graft of the fimbria.
McComb
P
P
Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, Canada.
Filmar
S
S
Pabuccu
R
R
D000714:Anastomosis, Surgical; D000818:Animals; D005187:Fallopian Tubes / Q000502:physiology / Q000637:transplantation* / Q000648:ultrastructure; D005260:Female; D008855:Microscopy, Electron, Scanning; D010537:Peritoneum / Q000601:surgery*; D011817:Rabbits