title: [Pregnancy-associated alpha2-glycoprotein (alpha2-PAG)--past, present and future].
abstract: The pregnancy-associated alpha 2-glycoprotein (alpha 2-PAG), first described 30 years ago, is a high-molecular neuramino-glycoprotein. Its serum concentration is normally low, but substantially increases during pregnancy and in some malignant tumour diseases. A review is given of occurrence and quantification of alpha 2-PAG under physiological and pathophysiological conditions, site of synthesis and localization, purification and physico-chemical properties, biological role and possible clinical use.
authors.affiliation: Klinik für Gynäkologie und Geburtshilfe, Bereichs Medizin der Ernst-Moritz-Arndt-Universität Greifswald.
authors.forename: W
authors.initials: W
authors.lastname: Straube
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000097:blood*; D011247:Pregnancy / Q000097:blood*; D011248:Pregnancy Complications / Q000097:blood*; D011257:Pregnancy Proteins / Q000032:analysis* / Q000302:isolation & purification / Q000502:physiology
chemical_list: D011257:Pregnancy Proteins
vernacular_title: Schwangerschaftsassoziiertes alpha 2-Glykoprotein (alpha 2-PAG)--Vergangenheit, Gegenwart und Zukunft.