[A case of thrombotic thrombocytopenic purpura].
Thrombocytopenic thrombotic purpura is a comparatively rare disease and little is known about its aetiopathogenesis. Once almost invariably negative, the prognosis has been changed by the introduction of plasmapheresis. A particularly complex clinical case is described and a number of conclusions are drawn from it: 1) there is no criterion for opting for any particular therapeutic approach; 2) evaluation of the clinical response is the only criterion for monitoring the effectiveness of ongoing treatment; 3) plasmapheresis is proposed as the treatment of choice; 4) vincristine is a useful alternative in the treatment of recalcitrant cases.
Meregalli
M
M
Presidio Ospedaliero di Garbagnate Milanese, Divisione di Medicina Generale II.
Gambelli
F
F
Torchio
G
G
Bocchia
M
M
D000328:Adult; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D010956:Plasmapheresis; D011697:Purpura, Thrombotic Thrombocytopenic / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D012008:Recurrence; D014750:Vincristine / Q000627:therapeutic use
D014750:Vincristine
Considerazioni a proposito di un caso di porpora trombotica trombocitopenica.