Sulfite sensitivity: relationship between sulfite plasma levels and bronchospasm: case report.
The present study describes a case of a 38-year-old nurse with asthma and probable sensitivity to sulfites. A double-blind challenge with sulfite and placebo was performed, pulmonary function tests were measured along with plasma levels of sulfites. A deficiency in sulfite-oxidase is suggested as the trigger mechanism of bronchospasm.
Acosta
R
R
Allergy and Immunology Service, Hospital de Especialidades, México, DF.
Granados
J
J
Mourelle
M
M
Perez-Alvarez
V
V
Quezada
E
E
D000328:Adult; D001249:Asthma / Q000139:chemically induced; D001986:Bronchial Spasm / Q000097:blood / Q000139:chemically induced*; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D006801:Humans; D008176:Lung Volume Measurements; D013447:Sulfites / Q000009:adverse effects* / Q000097:blood / Q000494:pharmacology; D013997:Time Factors
D013447:Sulfites; C005200:sodium metabisulfite