5-Fluorocytosine resistance in clinical isolates of Cryptococcus neoformans.
Thirty six clinical isolates of Cryptococcus neoformans were tested for their susceptibility to 5-fluorocytosine and amphotericin B by the determination of minimum inhibitory concentrations and minimum fungicidal concentrations. 22.2% of the isolates were resistant to 5-fluorocytosine and 36.1% indicated 5-fluorocytosine tolerance. All strains were sensitive to amphotericin B.
Chin
C S
CS
Cheong
Y M
YM
Wong
Y H
YH
D000666:Amphotericin B / Q000494:pharmacology; D003453:Cryptococcosis / Q000382:microbiology; D003454:Cryptococcus / Q000187:drug effects*; D003455:Cryptococcus neoformans / Q000187:drug effects*; D004352:Drug Resistance, Microbial; D005437:Flucytosine / Q000494:pharmacology*; D006801:Humans
D000666:Amphotericin B; D005437:Flucytosine