[Minimal change nephrotic syndrome in adults].
Twenty five adult patients with minimal changes disease proven at kidney biopsy and 13 of them older than 50 years of age are reported. Clinically, 32% of cases behaved as "impure" nephrotic syndrome, with no one case of established renal insufficiency; in nine cases, the process was antedated by a triggering event, usually infective episodes. In four cases who received no treatment, spontaneous remission was observed. All treated patients but one, initially responded to corticosteroid treatment in a period shorter than 1 month and 40% of patients presented maintained remission. There were no important complications derived from the disease nor from the treatment and at the end of the follow up only one patient died from a disease unrelated to the nephropathy.
Galicia Basart
M
M
Vallés Prats
M
M
Ferrer Prevosti
E
E
Piera Robert
L
L
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007668:Kidney / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009402:Nephrosis, Lipoid / Q000188:drug therapy / Q000473:pathology; D012008:Recurrence; D012189:Retrospective Studies; D013997:Time Factors
D000305:Adrenal Cortex Hormones
Síndrome nefrótico por cambios mínimos en el adulto.