[Protracted blood sugar increase in type 1 diabetics after brief but exhausting muscular exercise].
In eight type I diabetics-three of them under intensified insulin therapy and five on continuous subcutaneous insulin infusion (CSII)-blood-glucose concentrations fell significantly during 20-minute isometric and dynamic muscle work at about 50% of individual maximal work capacity and subsequent intensive exercise of five minutes until exhaustion. However, 6 1/2 hours later blood-glucose levels (221 +/- 39 mg/dl after isometric exercise and 219 +/- 24 mg/dl after dynamic exercise) were clearly above the mean level measured at the same time of day on the three preceding days of 138 +/- 12 mg/dl (P less than 0.05). No hypoglycaemia occurred. This blood-sugar profile can be explained by a significant rise in cortisol and growth hormone and their long-lasting blood-sugar raising effect.
Böhmer
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III. Medizinische Abteilung, Klinikum München-Bogenhausen.
Renner
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Hepp
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Landgraf
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D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000032:analysis*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D015444:Exercise; D005080:Exercise Test; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008875:Middle Aged; D013997:Time Factors
D001786:Blood Glucose; D013006:Growth Hormone; D006854:Hydrocortisone
Protrahierter Blutzuckeranstieg bei Typ-I-Diabetikern nach kurzdauernder erschöpfender Muskelarbeit.