title: [Methodological consideration on evaluation of lung cancer screening program: one-step process and two-step process].
abstract: A reasonable method to evaluate lung cancer screening program is to measure the reduction in death rate from lung cancer among those randomly allocated to screening program (one-step process). Alternative method is two-step process; step 1 is to measure what proportion of lung cancer patients, can be detected through screening and how early the screening can detected lung cancer patients, and step 2 is to delineate effectiveness of therapy following early detection. Advantages and disadvantages of the two processes were described in view of statistical power and sample size. In addition, a workplace-based screening program using chest X-ray files was mentioned as an example of step 1 of two-step process. The example also included economical consideration of the screening.
authors.affiliation: Dept. of Preventive Medicine, Nagoya Univ. School of Med.
authors.forename: N
authors.initials: N
authors.lastname: Hamajima
authors.forename: T
authors.initials: T
authors.lastname: Yamada
authors.forename: K
authors.initials: K
authors.lastname: Aoki
mesh_terms: D000328:Adult; D006801:Humans; D007564:Japan; D008175:Lung Neoplasms / Q000401:mortality / Q000517:prevention & control*; D008403:Mass Screening / Q000191:economics / Q000379:methods; D008875:Middle Aged; D015397:Program Evaluation / Q000379:methods; D013902:Radiography, Thoracic; D011897:Random Allocation; D013223:Statistics as Topic