[Myelopathy, polymyositis and systemic manifestations associated with the HTLV-I virus].
A case of HTLV-I associated myelopathy in a 51 year-old Haitian woman is reported. MRI showed high signals in the cerebral white matter on T2-weighted images. There also was clinical and electrophysiological evidence of myositis, and a biopsy of the quadriceps muscle showed dense inflammatory infiltrates surrounding several small perimysial blood vessels. The virus was not demonstrated in the muscle. The presence of several systemic abnormalities (polyclonal gammapathy, circulating immune complexes, Sjögren's syndrome) and the vasculitis suggest an immunopathological mechanism for this HTLV-I associated myositis.
Masson
C
C
Service de Neurologie, Hôpital Beaujon, Clichy.
Chaunu
M P
MP
Hénin
D
D
Masson
M
M
Cambier
J
J
D000936:Antigen-Antibody Complex / Q000032:analysis; D005260:Female; D015490:HTLV-I Infections / Q000150:complications* / Q000276:immunology; D006801:Humans; D008875:Middle Aged; D009220:Myositis / Q000209:etiology* / Q000276:immunology; D012859:Sjogren's Syndrome / Q000209:etiology / Q000276:immunology; D013118:Spinal Cord Diseases / Q000209:etiology* / Q000276:immunology
D000936:Antigen-Antibody Complex
Myéopathie, polymyosite et manifestations systémiques associées au virus HTLV-I.