title: Growth factor modulation of melanoma growth stimulatory activity mRNA expression in human malignant melanoma cells correlates with cell growth.
abstract: This report demonstrates that the expression of melanoma growth stimulatory activity (MGSA) mRNA can be modulated in a positive fashion in the Hs294T human melanoma cell line by PDGF and MGSA. There is close correlation between MGSA expression and the pattern of cell growth in Hs294T cells.
authors.affiliation: Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30033.
authors.forename: R
authors.initials: R
authors.lastname: Bordoni
authors.forename: G
authors.initials: G
authors.lastname: Thomas
authors.forename: A
authors.initials: A
authors.lastname: Richmond
mesh_terms: D015152:Blotting, Northern; D002455:Cell Division / Q000187:drug effects; D054360:Chemokine CXCL1; D019743:Chemokines, CXC; D006133:Growth Substances / Q000494:pharmacology*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins; D009363:Neoplasm Proteins / Q000235:genetics / Q000378:metabolism; D010982:Platelet-Derived Growth Factor / Q000494:pharmacology; D012333:RNA, Messenger / Q000235:genetics*; D014407:Tumor Cells, Cultured / Q000187:drug effects
chemical_list: C475829:CXCL1 protein, human; D054360:Chemokine CXCL1; D019743:Chemokines, CXC; D006133:Growth Substances; D036341:Intercellular Signaling Peptides and Proteins; D009363:Neoplasm Proteins; D010982:Platelet-Derived Growth Factor; D012333:RNA, Messenger