Effects of operations on lymphocyte glucocorticoid receptors.
The changes in the glucocorticoid receptor count of lymphocytes was studied in diseases requiring various surgical treatments. Based on their studies, authors established that the number of receptors increased in most cases after operation. The increase in receptor count depends on operative stress. As a result, the stimulated receptor count increased to double or triple that of the normal value, decreasing then to normal during the postoperative phase. The change in receptor count can be used in assessing the reactivity of the organism and prognosis.
Krasznai
A
A
Department of Surgery, Ujpest Hospital, Budapest, Hungary.
Krajcsi
P
P
Arányi
P
P
Horváth
I
I
D000328:Adult; D000368:Aged; D002763:Cholecystectomy; D005770:Gastrointestinal Neoplasms / Q000601:surgery; D006552:Hernia, Inguinal / Q000601:surgery; D006801:Humans; D007958:Leukocyte Count; D008214:Lymphocytes / Q000378:metabolism*; D008875:Middle Aged; D011965:Receptors, Glucocorticoid / Q000378:metabolism*; D013514:Surgical Procedures, Operative
D011965:Receptors, Glucocorticoid