[Increase of oxygen partial pressure and acceleration of wound healing by tetrachlorodecaoxide].
63 transcutaneous measurements of oxygen pressure and 36 series of infrared thermograms in 9 hypoxic wounds showed that topical administration of tetrachlorine decaoxide (TCDO) results in increased oxygen supply of the wound. This effect is associated with improvement of the skin temperature and decrease of the pathological temperature difference between the wound and the surrounding tissue. TCDO can induce physiological wound healing, since it improves the mechanisms of the immune defence system, wound cleansing, granulation, and epithelialization in slow-healing wounds.
Weiler-Mithoff
E M
EM
Medizinisches Zentrum für Hautkrankheiten, Abteilung für Haut-und Geschlechtskrankheiten der Philipps-Universität, Marburg.
Friederich
H C
HC
Horn
W
W
Issing
K
K
D000328:Adult; D000368:Aged; D000671:Amputation, Surgical; D001785:Blood Gas Monitoring, Transcutaneous; D002713:Chlorine / Q000008:administration & dosage*; D005260:Female; D005534:Foot Diseases / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010087:Oxides / Q000008:administration & dosage*; D011183:Postoperative Complications / Q000188:drug therapy; D012881:Skin Temperature / Q000187:drug effects; D012883:Skin Ulcer / Q000188:drug therapy*; D013686:Telemetry; D013817:Thermography; D014647:Varicose Ulcer / Q000188:drug therapy*; D014945:Wound Healing / Q000187:drug effects*
D010087:Oxides; D002713:Chlorine; C041955:tetrachlorodecaoxide
Steigerung des Sauerstoffpartialdruckes und Akzeleration der Wundheilung durch Tetrachlordecaoxid.