title: [Assessment of kidney function before cisplatin administration: the need for 24-hour urine collection].
abstract: Creatinine clearance as a measure of the glomerular filtration rate is calculated from the serum creatinine, urine creatinine concentration and the 24-h urine volume (MCC). Cockroft and Gault as well as Davila and Gardener have shown that estimation of the creatinine clearance (ECC) from the serum creatinine, age, sex, and weight of the patient is at least as accurate as measurement of creatinine clearance (MCC). ECC is not influenced by inaccurate collections of urine or incorrect analyses of urine creatinine. 125 MCC was investigated in 51 patients receiving cisplatin. If ECC is less than or equal to 80, then MCC should eliminate inaccurate urine collections. If the value of ECC exceeds 80, it is not necessary to measure MCC.
authors.affiliation: Universitätsklinik und Poliklinik für Hals-, Nasen- und Ohrenkranke, im Kopfklinikum Würzburg.
authors.forename: M
authors.initials: M
authors.lastname: Ptok
authors.forename: A
authors.initials: A
authors.lastname: Ptok
authors.forename: M
authors.initials: M
authors.lastname: Schwab
mesh_terms: D002940:Circadian Rhythm / Q000187:drug effects; D002945:Cisplatin / Q000008:administration & dosage / Q000009:adverse effects*; D003404:Creatinine / Q000652:urine*; D005260:Female; D005919:Glomerular Filtration Rate / Q000187:drug effects; D006258:Head and Neck Neoplasms / Q000188:drug therapy*; D006801:Humans; D007668:Kidney / Q000187:drug effects*; D007677:Kidney Function Tests / Q000379:methods*; D008297:Male; D012189:Retrospective Studies
chemical_list: D003404:Creatinine; D002945:Cisplatin
vernacular_title: Abschätzung der Nierenfunktion vor Cisplatingabe: Zur Notwendigkeit des 24-Stunden-Urinsammelns.