title: Fibroadenoma of the breast: a follow-up of conservative management.
abstract: This report details the outcome after clinical diagnosis of mammary fibroadenoma in 110 women aged under 35 years. After fine needle aspiration cytology, and subsequent exclusions and failures of follow-up, 92 lesions were observed for a mean of 47 weeks (range 13-90 weeks), with regular measurements until removal of persisting lesions at 12 months. Fifteen lesions disappeared and 56 had the classical histology of fibroadenoma, mean size 2.5 cm; 30 of the latter continued to grow throughout the study. Cytology is essential to exclude malignancy if conservative treatment is considered, and is helpful in identifying a benign lesion. A period longer than 12 months may be required for resolution of a fibroadenoma and removal under local anaesthesia as a day case offers a simple alternative.
authors.affiliation: Department of Surgery (Royal Infirmary of Edinburgh), University of Edinburgh, UK.
authors.forename: S
authors.initials: S
authors.lastname: Wilkinson
authors.forename: T J
authors.initials: TJ
authors.lastname: Anderson
authors.forename: E
authors.initials: E
authors.lastname: Rifkind
authors.forename: U
authors.initials: U
authors.lastname: Chetty
authors.forename: A P
authors.initials: AP
authors.lastname: Forrest
mesh_terms: D000232:Adenofibroma / Q000473:pathology / Q000628:therapy*; D000328:Adult; D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000473:pathology / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D011446:Prospective Studies