[Changes in the natural killer activity of lymphocytes in peripheral blood of patients with purulent-septic diseases under the effect of extracorporeal perfusion of pig spleen sections].
23 patients with pyo-septic diseases resistant to conservative therapy were treated by extracorporeal perfusion of xenospleen (EPXS). In 17 patients on EPXS a persistent detoxicating effect was achieved. 6 patients died. EPXS procedure was accompanied by a drop in medium-molecular lipid blood level and normalization of natural killer activity that was decreased considerably prior to EPXS. It is concluded that EPXS has a normalizing effect on the natural killer activity, which may be essential for resistance to infectious complications.
Zhidkov
K P
KP
Malygin
A M
AM
Dmitriev
N V
NV
Borison
A E
AE
Shevchenko
E V
EV
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D005112:Extracorporeal Circulation; D005260:Female; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D018805:Sepsis / Q000276:immunology / Q000628:therapy*; D013154:Spleen; D013552:Swine
Izmenenie estestvennoĭ killernoĭ aktivnosti limfotsitov perifericheskoĭ krovi u bol'nykh s gnoĭno-septicheskimi zabolevaniiami pod vliianiem ékstrakorporal'noĭ perfuzii srezov selezenki svin'i.