[Circadian rhythm of blood acetylcholinesterase after administration of organophosphate compounds during hypokinesia].
Circadian and ultradian rhythms of blood acetylcholinesterase (ACE) and rectal temperature were investigated during hypokinesia and administration of a toxic organic phosphate compound in various doses. Hypokinesia was found to produce a strong desynchronizing effect on ACE and thermal regulation. It is maintained that the use of chemicals with a well documented mechanism of action may yield reliable information about biorhythm restructuring in response to exogenous effects. It is emphasized that biorhythm changes should be taken into consideration when arranging work schedules in hypokinetic conditions.
Dobriian
B B
BB
Shpirt
M B
MB
Eroshenko
V Sh
VSh
Abdashimov
K A
KA
D000110:Acetylcholinesterase / Q000097:blood*; D000279:Administration, Cutaneous; D000818:Animals; D002800:Cholinesterase Inhibitors; D002940:Circadian Rhythm; D007103:Immobilization; D008297:Male; D063086:Organothiophosphates / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000633:toxicity*; D009946:Organothiophosphorus Compounds / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000633:toxicity*; D051381:Rats; D012869:Skin Absorption
D002800:Cholinesterase Inhibitors; D063086:Organothiophosphates; D009946:Organothiophosphorus Compounds; C009532:trichlorometaphos-3; C006863:butyl phosphorotrithioate; D000110:Acetylcholinesterase
Sutochnaia ritmika atsetilkholinésterazy krovi pri vozdeĭstvii fosfororganicheskogo soedineniia pri gipokinezii.