title: 5-ASA enema therapy.
abstract: 5-Aminosalicylic acid (5-ASA) enema therapy has been a direct extension of our understanding of the pharmacology and metabolism of sulfasalazine. Clinical studies have documented the efficacy and safety of topical 5-ASA therapy in distal ulcerative colitis. Future clinical experience should clarify the role of topical 5-ASA in a variety of inflammatory bowel disease syndromes.
authors.affiliation: University of Chicago Medical Center, Illinois 60637.
authors.forename: S B
authors.initials: SB
authors.lastname: Hanauer
mesh_terms: D000636:Aminosalicylic Acids / Q000008:administration & dosage* / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage* / Q000627:therapeutic use; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D004733:Enema; D006801:Humans; D019804:Mesalamine
chemical_list: D000636:Aminosalicylic Acids; D000894:Anti-Inflammatory Agents, Non-Steroidal; D019804:Mesalamine