Effect of maternal avoidance of eggs, cow's milk and fish during lactation upon allergic manifestations in infants.
Atopic/allergic manifestations and skin-prick tests (SPT) to egg white, cow's milk (CM) and fish were evaluated during the first 18 months of life in two matched groups of infants with a family history of atopy/allergy. In one group (n = 65) the mothers had a diet free from eggs, CM and fish during the first 3 months postpartum, whereas the mothers in the other group (n = 50) consumed an ordinary diet. The diet of the infants was similar in both groups, i.e. CM was not supplied until 6 months of age, and eggs and fish not until 9 months of age. The incidence of atopic dermatitis was significantly lower in the maternal diet group during the first 6 months postpartum (10.8 and 28%, respectively) but not after that age. Other atopic/allergic manifestations did not differ and the number of positive SPT to egg white, CM or fish at 9 months of age was similar in both groups.
Hattevig
G
G
Department of Pediatrics, Central Hospital, Skövde, Sweden.
Kjellman
B
B
Sigurs
N
N
Björkstén
B
B
Kjellman
N I
NI
D000818:Animals; D001249:Asthma / Q000209:etiology; D001942:Breast Feeding; D003876:Dermatitis, Atopic / Q000209:etiology*; D015387:Egg Proteins, Dietary / Q000008:administration & dosage*; D005260:Female; D005399:Fishes; D005512:Food Hypersensitivity / Q000209:etiology*; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology*; D007073:Immunoglobulin E / Q000032:analysis; D007223:Infant; D007225:Infant Food; D007231:Infant, Newborn; D007774:Lactation; D008892:Milk; D011247:Pregnancy
D015387:Egg Proteins, Dietary; D007073:Immunoglobulin E