title: [Effect of a 30-day period of hypokinesia on various physiologic and biochemical indicators during maximal physical load].
abstract: Exercise tolerance of test subjects who remained bed rested (Group A) and who exercised while being supine (Group B) was measured before and after 30-day head-down tilt (-8 degrees). Special attention was given to the parameters that characterize energy supply of working muscles. The data obtained after 30-day bed rest did not reveal any changes in the Group B subjects and showed the following changes in the Group A subjects: maximum oxygen consumption decreased by 10.1% (p less than 0.05), the time within which the anaerobic metabolism threshold was attained decreased by 17.2% (p less than 0.05), and lactate concentration at the workload end decreased by 24.7%, while the pyruvate concentration and the lactate/pyruvate ratio remained unchanged. The results indicate that prolonged aerobic workload after 30-day bed rest seems to be limited by functional changes in oxygen transport rather than by the factors associated with changes in energy supply of working muscles.
authors.forename: V P
authors.initials: VP
authors.lastname: Buzulina
authors.forename: G V
authors.initials: GV
authors.lastname: Machinskiĭ
authors.forename: E A
authors.initials: EA
authors.lastname: Nosova
authors.forename: V I
authors.initials: VI
authors.lastname: Stepantsov
mesh_terms: D000328:Adult; D005080:Exercise Test; D006801:Humans; D007103:Immobilization; D007773:Lactates / Q000097:blood; D007866:Leg; D008297:Male; D009132:Muscles / Q000378:metabolism*; D010101:Oxygen Consumption; D005082:Physical Exertion; D011187:Posture; D011773:Pyruvates / Q000097:blood; D013997:Time Factors
chemical_list: D007773:Lactates; D011773:Pyruvates
vernacular_title: Vliianie 30-sutochnoĭ gipokinezii na nekotorye fiziologicheskie i biokhimicheskie pokazateli pri maksimal'noĭ fizicheskoĭ nagruzke.