Fibronectin content of the annulus fibrosus in diabetic and non-diabetic sand rats.
Annulus fibrosus of intervertebral discs from diabetic and non-diabetic sand rats were examined by microspectrophotometry for fibronectin content. This was higher in the diabetic animals both in the dorsal and ventral parts and in the outer and inner lamellae of the annulus. It is suggested that diabetes-related changes in fibronectin are similar to changes in annular collagen observed in species other than sand rats.
Silberberg
R
R
Department of Pathology, Hebrew University, Jerusalem, Israel.
Meier-Ruge
W
W
Odermatt
B
B
D000818:Animals; D003411:Arvicolinae; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism*; D005353:Fibronectins / Q000032:analysis* / Q000378:metabolism; D007403:Intervertebral Disc / Q000032:analysis* / Q000378:metabolism; D015591:Microspectrophotometry
D005353:Fibronectins