Genetic code preferentially conserves long-range interactions among the amino acids.
The physical properties of amino acids were investigated in order to evaluate their possible relationship to the assignment of codons for amino acids in the genetic code. A comparison of the interconversion probability between amino acids and the distances between the amino acids for individual physical properties revealed a striking hierarchy among the physical properties. Surprisingly, it is the long-range/solvent interactions and not the short-range/stereochemical properties which are preferentially conserved in the genetic code.
Sitaramam
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V
Department of Zoology, University of Poona, India.
D000596:Amino Acids / Q000235:genetics*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003062:Codon; D005815:Genetic Code; D011336:Probability; D012333:RNA, Messenger
D000596:Amino Acids; D003062:Codon; D012333:RNA, Messenger