title: Zinc methionine for ruminants: relative bioavailability of zinc in lambs and effects of growth and performance of growing heifers.
abstract: Studies were conducted to evaluate zinc methionine (ZnMet) as a source of Zn for ruminants. Experiment 1 compared the availability of Zn in ZnMet and zinc oxide (ZnO) in lambs fed a semi-purified diet deficient in Zn. Based on growth rate and animal performance, plasma Zn and plasma alkaline phosphatase activity, no differences in Zn availability were detected between the two Zn sources. Apparent absorption of Zn also was similar, but Zn retention was higher (P less than .01) in lambs fed ZnMet because of a tendency for lower urinary Zn excretion (P less than .19) in this group. Zinc absorption and retention by lambs were similar for the two Zn sources in Exp. 2 when 20 mg Zn/kg was added to an orchardgrass hay-based diet containing 30 mg Zn/kg. In Exp. 3, lambs were dosed orally with 300 mg of Zn as ZnO or ZnMet, and the increase in plasma Zn following dosing was monitored. The increase in plasma Zn above predosing values was similar at 6 h but was higher at 12 (P less than .10) and 24 h (P less than .05) postdosing in lambs given ZnMet. Thirty-six Hereford x Simmental heifers (271 kg) were used in Exp. 4 to determine the influence of supplementing Zn (25 mg/kg) as ZnO or ZnMet of growth performance and Zn status. Heifers were fed a corn silage-based diet that contained 23.1 mg Zn/kg during the 126-d study. Zinc supplementation to the basal diet increased (P less than .05) gain and feed/gain during the first 56 d, but not for the entire 126-d study.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Dept. of Anim. Sci., North Carolina State University, Raleigh 27695.
authors.forename: J W
authors.initials: JW
authors.lastname: Spears
mesh_terms: D000821:Animal Feed; D000818:Animals; D001682:Biological Availability; D001835:Body Weight / Q000187:drug effects; D002417:Cattle / Q000378:metabolism* / Q000502:physiology; D004032:Diet; D005260:Female; D005527:Food, Fortified; D008297:Male; D008715:Methionine / Q000493:pharmacokinetics* / Q000494:pharmacology; D011897:Random Allocation; D012741:Sexual Maturation / Q000187:drug effects; D012756:Sheep / Q000254:growth & development / Q000378:metabolism*; D015032:Zinc / Q000097:blood / Q000493:pharmacokinetics*; D015034:Zinc Oxide / Q000493:pharmacokinetics / Q000494:pharmacology
chemical_list: D008715:Methionine; D015032:Zinc; D015034:Zinc Oxide