Transferable trimethoprim resistance of shigellae encountered in Vellore (south India).
Shigella flexneri and Sh. shigae which are the two most common shigellae encountered in Vellore (south India) were found to exhibit resistance to trimethoprim and trimethoprim-sulphamethoxazole. Eighty four per cent of this was high level resistance. Transfer studies conducted with these strains indicated that this high level resistance is plasmid mediated.
Jesudason
M V
MV
Joseph
D
D
Koshi
G
G
D004352:Drug Resistance, Microbial / Q000235:genetics; D006801:Humans; D007194:India; D011815:R Factors; D012760:Shigella / Q000187:drug effects*; D012763:Shigella flexneri / Q000187:drug effects*; D014295:Trimethoprim / Q000494:pharmacology*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000494:pharmacology*
D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim