title: HTLV-1 seroprevalence in AIDS patients and in HIV-1 seropositive and seronegative subjects at risk for AIDS in northern Italy.
abstract: Sera of 1023 subjects belonging to categories at risk for AIDS, positive for HIV-1, were tested for antibodies to human T-cell leukemia virus (HTLV-1) by ELISA, Western blotting, and radioimmunoprecipitation (RIP) assay. Sera of these subjects were positive for antibodies to HTLV-1 in a percentage of 18.54%. Nine out of 18 sera from patients with AIDS had antibodies to HTLV-1 (50%). Sera of 207 intravenous drug abusers and 64 homosexual males, seronegative for HIV-1, were tested for antibodies to HTLV-1 and 6.7% of intravenous drug abusers and 7.8% of homosexual males were found to be HTLV-1 antibody positive, showing that HTLV-1 infection occurred independently of HIV-1 and HIV-2 infections. In fact the same HIV-1 seronegative patients were also tested for the presence of antibodies to HIV-2 and none of them was found to be positive.
authors.affiliation: Istituto di Microbiologia, Università di Brescia, Italy.
authors.forename: N
authors.initials: N
authors.lastname: Manca
authors.forename: A
authors.initials: A
authors.lastname: Caruso
authors.forename: C
authors.initials: C
authors.lastname: Bonfanti
authors.forename: E
authors.initials: E
authors.lastname: Savoldi
authors.forename: R
authors.initials: R
authors.lastname: Li Vigni
authors.forename: F
authors.initials: F
authors.lastname: Pirali
authors.forename: P L
authors.initials: PL
authors.lastname: Sapelli
authors.forename: A
authors.initials: A
authors.lastname: Turano
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology* / Q000635:transmission; D015483:HIV Antibodies / Q000032:analysis*; D006679:HIV Seropositivity / Q000276:immunology* / Q000635:transmission; D015497:HIV-1 / Q000276:immunology*; D015481:HTLV-I Antibodies / Q000032:analysis*; D006716:Homosexuality; D015368:Human T-lymphotropic virus 1 / Q000276:immunology*; D006801:Humans; D007558:Italy; D012307:Risk Factors; D019966:Substance-Related Disorders / Q000276:immunology
chemical_list: D015483:HIV Antibodies; D015481:HTLV-I Antibodies