title: Effects of running the Boston marathon on plasma concentrations of large neutral amino acids.
abstract: Plasma large neutral amino acid concentrations were measured in thirty-seven subjects before and after completing the Boston Marathon. Concentrations of tyrosine, phenylalanine, and methionine increased, as did their "plasma ratios" (i.e., the ratio of each amino acid's concentration to the summed plasma concentrations of the other large neutral amino acids which compete with it for brain uptake). No changes were noted in the plasma concentrations of tryptophan, leucine, isoleucine, nor valine; however, the "plasma ratios" of acid patterns may influence neurotransmitter synthesis.
authors.affiliation: Laboratory of Neuroendocrine Regulation, Massachusetts Institute of Technology, Cambridge.
authors.forename: L A
authors.initials: LA
authors.lastname: Conlay
authors.forename: R J
authors.initials: RJ
authors.lastname: Wurtman
authors.forename: I
authors.initials: I
authors.lastname: Lopez G-Coviella
authors.forename: J K
authors.initials: JK
authors.lastname: Blusztajn
authors.forename: C A
authors.initials: CA
authors.lastname: Vacanti
authors.forename: M
authors.initials: M
authors.lastname: Logue
authors.forename: M
authors.initials: M
authors.lastname: During
authors.forename: B
authors.initials: B
authors.lastname: Caballero
authors.forename: T J
authors.initials: TJ
authors.lastname: Maher
authors.forename: G
authors.initials: G
authors.lastname: Evoniuk
mesh_terms: D000596:Amino Acids / Q000097:blood*; D006801:Humans; D007532:Isoleucine / Q000097:blood; D007930:Leucine / Q000097:blood; D008715:Methionine / Q000097:blood; D010649:Phenylalanine / Q000097:blood; D005082:Physical Exertion; D012016:Reference Values; D012420:Running; D014364:Tryptophan / Q000097:blood; D014443:Tyrosine / Q000097:blood; D014633:Valine / Q000097:blood
chemical_list: D000596:Amino Acids; D007532:Isoleucine; D014443:Tyrosine; D010649:Phenylalanine; D014364:Tryptophan; D008715:Methionine; D007930:Leucine; D014633:Valine