title: [Antibiotic therapy in hip endoprosthesis surgery].
abstract: A 5-point programme preventing deep infection following total hip replacement is presented. All of the single-stage procedures (3948) were subjected to analysis. An infection rate after total hip replacement of 0.07% in the first half year and long-term follow-up results of 1.29% were found using a laminar air flow system without prophylactic antibiotics. One-stage reimplantation was performed in combination with local administration of antibiotics, followed by a postoperative regimen of alternating administration of 2 antimicrobial drugs for the treatment of deep periprosthetic infection. Over a follow-up period of one to 9 years there was no evidence of recurrence of infection in 80% of cases.
authors.affiliation: Orthopädische Universitätsklinik, Innsbruck.
authors.forename: M
authors.initials: M
authors.lastname: Krismer
mesh_terms: D001424:Bacterial Infections / Q000188:drug therapy*; D002511:Cephalosporins / Q000627:therapeutic use; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D006622:Hip Prosthesis; D006801:Humans; D010068:Oxacillin / Q000627:therapeutic use; D010400:Penicillin G / Q000627:therapeutic use; D013530:Surgical Wound Infection / Q000188:drug therapy*
chemical_list: D002511:Cephalosporins; D010400:Penicillin G; D010068:Oxacillin
vernacular_title: Die Antibiotikatherapie in der Hüftendoprothetik.