[An autopsied case of malignant paraganglioma of the posterior thoracic cavity].
An autopsied case of a malignant paraganglioma of the posterior thoracic cavity is reported. A 68-year-old man had complained of chest discomfort, and serial examinations revealed a functioning paraganglioma with bone metastasis. After death a pathological examination revealed that the tumors consisted of alveolarly arranged cells and well developed capillary vessels. Numerous neurosecretory granules were observed on viewing by electron microscopy. An immunohistochemical examination showed that most of the tumor cells were positive for NSE, while only a few cells were positive for the S-100 protein. These results indicate that a paraganglioma originating from the aortic sympathetic paraganglia had similar features of a carcinoid and a neuroblastoma.
Kitazawa
S
S
Dept. of Pathology, Kobe National Hospital.
Maeda
S
S
Horio
M
M
Sugiyama
T
T
D000310:Adrenal Gland Neoplasms / Q000032:analysis; D000368:Aged; D002276:Carcinoid Tumor / Q000032:analysis; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009447:Neuroblastoma / Q000032:analysis; D010235:Paraganglioma / Q000032:analysis / Q000473:pathology* / Q000648:ultrastructure; D010673:Pheochromocytoma / Q000032:analysis; D010751:Phosphopyruvate Hydratase / Q000032:analysis; D009418:S100 Proteins / Q000032:analysis; D013899:Thoracic Neoplasms / Q000032:analysis / Q000473:pathology* / Q000648:ultrastructure
D009418:S100 Proteins; D010751:Phosphopyruvate Hydratase