title: Cognitive impairment after neuroleptanalgesia in cataract surgery.
abstract: This study was undertaken to evaluate the mental recovery of patients following cataract operations under neuroleptanalgesia. Mental function was assessed by Mini-Mental State (MMS) preoperatively and at 6 and 24 hours postoperatively. Preoperatively, 18.7% of the elderly had cognitive impairment of mental function while none in the younger group had any impairment (P less than 0.02). At six hours postoperatively, 29.7% of the elderly had cognitive impairment compared with 4% of the younger group (P less than 0.01). At 24 hours postoperatively, the percentage of elderly and younger patients with cognitive impairment had returned to preoperative levels. Baseline score and age were found to be significant predictors (P less than 0.004) of the 6-hour score and 24-hour score. In conclusion, cognitive impairment of mental function occurred in patients undergoing cataract operation with retrobulbar block and intravenous sedation at 6 hours postoperatively; MMS has the potential for use as a screening preoperative test for outpatients to identify those at risk for developing cognitive impairment.
authors.affiliation: Department of Anesthesia, Toronto Hospital, University of Toronto, Ontario, Canada.
authors.forename: F
authors.initials: F
authors.lastname: Chung
authors.forename: P A
authors.initials: PA
authors.lastname: Lavelle
authors.forename: S
authors.initials: S
authors.lastname: McDonald
authors.forename: A
authors.initials: A
authors.lastname: Chung
authors.forename: N J
authors.initials: NJ
authors.lastname: McDonald
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D002387:Cataract Extraction; D003072:Cognition Disorders / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009458:Neuroleptanalgesia / Q000009:adverse effects*; D011183:Postoperative Complications; D012044:Regression Analysis