title: Lipid peroxidation in human diseases: evidence of red cell oxidative stress after circulatory shock.
abstract: Erythrocytes obtained from human patients with circulatory shock of different aetiology consistently showed a strong increase in lipid peroxidation-derived aldehydes in comparison with red cells of normal adults. The highly toxic compound 4-hydroxynonenal has been recovered exclusively in the erythrocytes of the patients.
authors.affiliation: Department of Experimental Medicine and Oncology of the University, Torino, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Poli
authors.forename: F
authors.initials: F
authors.lastname: Biasi
authors.forename: E
authors.initials: E
authors.lastname: Chiarpotto
authors.forename: M U
authors.initials: MU
authors.lastname: Dianzani
authors.forename: A
authors.initials: A
authors.lastname: De Luca
authors.forename: H
authors.initials: H
authors.lastname: Esterbauer
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000447:Aldehydes / Q000097:blood; D002851:Chromatography, High Pressure Liquid; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D010084:Oxidation-Reduction; D012769:Shock / Q000097:blood*; D012770:Shock, Cardiogenic / Q000097:blood; D013053:Spectrophotometry
chemical_list: D000447:Aldehydes; D008315:Malondialdehyde; C027576:4-hydroxy-2-nonenal