title: The third histamine receptor. Highly potent and selective ligands.
abstract: The third histamine receptor was first identified on brain neurons and seems also to be present in other cells such as the lung mast cells. Hence the novel and potent H3 receptor agonist (R)-alpha-methylhistamine might find therapeutic applications in allergic diseases.
authors.affiliation: Unité 109 de Neurobiologie et Pharmacologie, Centre Paul-Broca, INSERM, Paris, France.
authors.forename: J M
authors.initials: JM
authors.lastname: Arrang
authors.forename: M
authors.initials: M
authors.lastname: Garbarg
authors.forename: J C
authors.initials: JC
authors.lastname: Lancelot
authors.forename: J M
authors.initials: JM
authors.lastname: Lecomte
authors.forename: H
authors.initials: H
authors.lastname: Pollard
authors.forename: M
authors.initials: M
authors.lastname: Robba
authors.forename: W
authors.initials: W
authors.lastname: Schunack
authors.forename: J C
authors.initials: JC
authors.lastname: Schwartz
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology; D006168:Guinea Pigs; D066298:In Vitro Techniques; D008024:Ligands; D008168:Lung / Q000502:physiology; D008407:Mast Cells / Q000502:physiology; D008761:Methylhistamines / Q000494:pharmacology*; D010880:Piperidines / Q000494:pharmacology; D051381:Rats; D011968:Receptors, Histamine / Q000145:classification / Q000187:drug effects / Q000378:metabolism*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D008024:Ligands; D008761:Methylhistamines; D010880:Piperidines; D011968:Receptors, Histamine; C052075:thioperamide