title: [Collagen metabolism in the skin and bone tissue of rats after a 7-day space flight].
abstract: Collagen metabolism in the skin and bone (femur) of 3-month male rats of the SPF Wistar strain was investigated. Bone of the flown rats showed an increase in pepsin-soluble collagen and a decrease in pepsin-insoluble collagen. The skin of the flown rats exhibited opposite changes. Both the skin and bone of the flown animals showed an increase of type III collagen (in the pepsin-soluble and pepsin-insoluble fractions). Similar changes were previously observed in female rats, that were launched while being pregnant, and in their offspring.
authors.forename: I
authors.initials: I
authors.lastname: Pospishilova
authors.forename: M
authors.initials: M
authors.lastname: Poslishil
authors.forename: L V
authors.initials: LV
authors.lastname: Serova
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000378:metabolism*; D003094:Collagen / Q000172:deficiency / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012867:Skin / Q000378:metabolism*; D013026:Space Flight; D013997:Time Factors
chemical_list: D003094:Collagen
vernacular_title: Metabolizm kollagena v kozhe i kostnoĭ tkani krys posle 7-dnevnogo kosmicheskogo poleta.