[Ungueal capillaroscopy in fasciitis with eosinophilia: a distinctive feature of systemic scleroderma. Apropos of 15 cases].
Eosinophilic fasciitis (EF) is a recently described disease whose distinction from progressive systemic sclerosis (PSS) is still being discussed. PSS has a characteristic microcirculation pattern. We performed nailfold microscopy on 15 patients with EF and compared the results to those of 98 PSS patients and 75 normal control subjects. EF patients have a normal microcirculation pattern (13/15) or discrete, non-specific anomalies: none had the typical capillary pattern associated with PSS and associated diseases. The findings of this study justify making a distinction between EF and PSS and demonstrate that nail fold microscopy can be a useful tool for an early differential diagnosis between these two disorders.
Herson
S
S
Service de Médicine Interne de la Salpêtrière, Groupe-Hospitalier Pitié-Salpêtrière, Paris.
Brechignac
S
S
Piette
J C
JC
Mouthon
J M
JM
Coutellier
A
A
Bletry
O
O
Godeau
P
P
D000328:Adult; D000368:Aged; D002196:Capillaries / Q000473:pathology; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000175:diagnosis*; D005208:Fasciitis / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008853:Microscopy; D008875:Middle Aged; D009262:Nails / Q000098:blood supply*; D012595:Scleroderma, Systemic / Q000175:diagnosis* / Q000473:pathology; D016037:Single-Blind Method
Capillaroscopie unguéale au cours de la fasciite avec éosinophilie: un élément distinctif d'avec la sclérodermie systémique. A propos de 15 cas.