title: [Metabolism of the connective tissue in generalized scleroderma].
abstract: Scleroderma, a connective tissue disorder is characterized by vascular and interstitial reaction with deposition of matrix components. Abnormalities in collagen and glycosaminoglycan structure and metabolism, and regulatory processes of their biosynthesis in scleroderma are reviewed.
authors.forename: E J
authors.initials: EJ
authors.lastname: Kucharz
authors.forename: S J
authors.initials: SJ
authors.lastname: Sierakowski
mesh_terms: D003094:Collagen / Q000378:metabolism*; D003238:Connective Tissue / Q000378:metabolism*; D006025:Glycosaminoglycans / Q000378:metabolism*; D006801:Humans; D006909:Hydroxyproline / Q000652:urine; D012595:Scleroderma, Systemic / Q000378:metabolism*; D012867:Skin / Q000378:metabolism*
chemical_list: D006025:Glycosaminoglycans; D003094:Collagen; D006909:Hydroxyproline
vernacular_title: Metabolizm tkanki Lacznej w twardzinie uogólnionej.