Human placental xenobiotic and steroid biotransformations catalyzed by cytochrome P450, epoxide hydrolase, and glutathione S-transferase activities and their relationships to maternal cigarette smoking.
Pasanen
M
M
Department of Pharmacology and Toxicology, University of Oulu, Finland.
Pelkonen
O
O
D001711:Biotransformation; D002384:Catalysis; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004851:Epoxide Hydrolases / Q000378:metabolism; D005260:Female; D005982:Glutathione Transferase / Q000378:metabolism; D006801:Humans; D008431:Maternal-Fetal Exchange; D010920:Placenta / Q000201:enzymology / Q000378:metabolism*; D011247:Pregnancy; D012907:Smoking / Q000378:metabolism*; D013256:Steroids / Q000378:metabolism / Q000493:pharmacokinetics*; D015262:Xenobiotics / Q000493:pharmacokinetics*
D013256:Steroids; D015262:Xenobiotics; D003577:Cytochrome P-450 Enzyme System; D005982:Glutathione Transferase; D004851:Epoxide Hydrolases