title: Orosomucoid (ORM) typing by isoelectric focusing: description of two new alleles in a German population and thermostability in bloodstains.
abstract: The genetic polymorphism of serum orosomucoid (ORM) was studied in 168 unrelated German individuals using isoelectric focusing followed by immunoprinting. Two new alleles, tentatively designated ORM1*14 and ORM2*13, were identified. The method was successfully applied to demonstrate ORM1 types in dried bloodstains. Each type of ORM1 was also correctly determined in bloodstains heated at 130 degrees C for 30 min. The results indicated that ORM1 is a new powerful genetic marker system for the grouping of bloodstains.
authors.affiliation: Department of Forensic Medicine, Yamagata University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Umetsu
authors.forename: I
authors.initials: I
authors.lastname: Yuasa
authors.forename: K
authors.initials: K
authors.lastname: Nishi
authors.forename: B
authors.initials: B
authors.lastname: Brinkmann
authors.forename: T
authors.initials: T
authors.lastname: Suzuki
mesh_terms: D000483:Alleles; D001801:Blood Stains; D005787:Gene Frequency; D005828:Genetics, Population; D005860:Germany, West; D006801:Humans; D007525:Isoelectric Focusing; D009961:Orosomucoid / Q000235:genetics*; D010641:Phenotype; D011110:Polymorphism, Genetic
chemical_list: D009961:Orosomucoid