Translocations involving chromosomes 2 and 13 in benign and malignant cartilaginous neoplasms.
Cytogenetic analysis of a chrondromyxoid fibroma of bone and an extraskeletal myxoid chondrosarcoma revealed clonal chromosomal rearrangements involving chromosomes 2 and 13. The significance of these findings in these neoplasms of cartilaginous origin, one benign and one malignant, is discussed.
Bridge
J A
JA
Department of Pathology, University of Kansas Medical Center, Kansas City 66103.
Sanger
W G
WG
Neff
J R
JR
D000328:Adult; D001859:Bone Neoplasms / Q000235:genetics*; D002812:Chondroma / Q000235:genetics*; D002813:Chondrosarcoma / Q000235:genetics*; D002882:Chromosomes, Human, Pair 13; D002889:Chromosomes, Human, Pair 2; D006801:Humans; D008297:Male; D008875:Middle Aged; D014178:Translocation, Genetic