title: Early results of local application of 13-cis retinoic acid in the treatment of leukoplakia of the vulva.
abstract: A group of 35 patients with leukoplakia of the vulva was treated with 13-cis retinoic acid applied topically. Complete or partial remission occurred in 17 patients. Parallel determination of retinol level in sera revealed its increased value as compared to healthy persons.
authors.affiliation: Cancer Center Maria Skłodowska Curie Institute - Warsaw, Poland.
authors.forename: S W
authors.initials: SW
authors.lastname: Kwaśniewski
authors.forename: J
authors.initials: J
authors.lastname: Stelmachów
authors.forename: P
authors.initials: P
authors.lastname: Janik
authors.forename: M
authors.initials: M
authors.lastname: Kugaczewska
authors.forename: J
authors.initials: J
authors.lastname: Sawicki
authors.forename: M
authors.initials: M
authors.lastname: Golanek
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000368:Aged; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007971:Leukoplakia / Q000188:drug therapy* / Q000473:pathology; D008875:Middle Aged; D014212:Tretinoin / Q000008:administration & dosage* / Q000627:therapeutic use; D014846:Vulvar Neoplasms / Q000188:drug therapy* / Q000473:pathology
chemical_list: D014212:Tretinoin