[Male hypogonadism in children and adolescents: diagnostic assessment and therapy indications].
Testicular hormones, produced by hypothalamic-pituitary-gonadal axis activation, induce male development during embryogenesis and sexual maturation at puberty. As a consequence, any lesion at different levels of the axis is responsible for different clinical alterations, depending on the phase of life in which it develops, from early gestation to adult life. The evaluation of a hypogonadic male is complex and often diagnostic procedures only discriminate the level of damage but not the cause. Standardized and widely accepted therapies for specific forms of hypogonadism are briefly exposed. Three cases of hypogonadotropic hypogonadism are reported.
Braggion
F
F
Istituto Scientifico H. San Raffaele, Università di Milano, Italia.
Gargantini
L
L
Calzi
P
P
Chiumello
G
G
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D006063:Chorionic Gonadotropin / Q000627:therapeutic use; D006062:Gonadotropins / Q000097:blood; D006801:Humans; D007006:Hypogonadism / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D007223:Infant; D007231:Infant, Newborn; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D010906:Pituitary Hormone-Releasing Hormones; D011388:Prolactin / Q000097:blood; D013739:Testosterone / Q000097:blood / Q000627:therapeutic use
D006063:Chorionic Gonadotropin; D006062:Gonadotropins; D010906:Pituitary Hormone-Releasing Hormones; D013739:Testosterone; D011388:Prolactin; D007986:Luteinizing Hormone
Ipogonadismo maschile nel bambino e nell'adolescente: inquadramento diagnostico e cenni di terapia.