title: A close relationship between microvilli and metabolic cooperation deficiency in embryonal carcinoma cells.
abstract: A revertant clone has been isolated from the metabolic cooperation-deficient embryonal carcinoma clone PT2md1. In PT2md1, its cooperation-competent parent, and its cooperation-competent revertant an inverse correlation has been demonstrated between cooperation competence and the incidence of microvilli. This demonstration, together with a similar correlation previously reported in an independently isolated series of cell lines, establishes a close causal relationship between the incidence of microvilli and communication deficiency.
authors.affiliation: Department of Pathology, University Medical School, Edinburgh, Scotland.
authors.forename: I F
authors.initials: IF
authors.lastname: Purcell
authors.forename: T A
authors.initials: TA
authors.lastname: Smith
authors.forename: C E
authors.initials: CE
authors.lastname: Patek
authors.forename: M L
authors.initials: ML
authors.lastname: Hooper
mesh_terms: D000818:Animals; D002450:Cell Communication; D007365:Intercellular Junctions / Q000502:physiology*; D008871:Microvilli / Q000502:physiology*; D013499:Surface Properties; D013724:Teratoma / Q000378:metabolism* / Q000648:ultrastructure; D014407:Tumor Cells, Cultured