Oxidative metabolism of rabbit and rat intestine with short chain fatty acids and glucose: an evaluation of data analysis.
1. Glucose sustained VO2 of rabbit ileum, caecum, and distal colon better than SCFAs. 2. In rabbit proximal colon, while VO2 was stimulated in the presence of butyrate it was not sustained. 3. Rat caecum utilized glucose but it was not necessarily the best substrate for either the ileum or colon of this species and SCFAs appeared to stimulate VO2 of rat ileum and inhibit VO2 in rat caecum and colon. 4. It was concluded from the comparison of the two methods of data analyses that curve-fitting the data by a negative exponential equation provides for a more clear and in depth interpretation of such studies.
Hatch
M
M
Department of Zoology and Physiology, Louisiana State University, Baton Rouge, LA 70803.
Geaghan
J P
JP
D000818:Animals; D003627:Data Interpretation, Statistical; D005227:Fatty Acids; D005232:Fatty Acids, Volatile / Q000378:metabolism*; D005260:Female; D005947:Glucose / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000378:metabolism*; D008297:Male; D010101:Oxygen Consumption; D011817:Rabbits; D051381:Rats; D011919:Rats, Inbred Strains
D005227:Fatty Acids; D005232:Fatty Acids, Volatile; D005947:Glucose