title: Effects of ethanol and acetaldehyde on cultured pre-implantation mouse embryos.
abstract: Pre-implantation 2-cell stage mouse embryos, obtained from superovulated CF-1 mice, were exposed to ethanol and acetaldehyde through the culture medium for 60 min followed by a 105-h incubation period. Control and ethanol exposed embryos survived equally well in ethanol concentrations as high as 800 mg/100 ml medium and acetaldehyde levels up to 10 mg/100 ml medium.
authors.affiliation: Department of Biology, East Carolina University, Greenville, North Carolina 27858.
authors.forename: G W
authors.initials: GW
authors.lastname: Kalmus
authors.forename: C C
authors.initials: CC
authors.lastname: Buckenmaier
mesh_terms: D000079:Acetaldehyde / Q000494:pharmacology*; D000818:Animals; D001755:Blastocyst / Q000166:cytology* / Q000187:drug effects / Q000502:physiology; D002470:Cell Survival / Q000187:drug effects; D047108:Embryonic Development / Q000187:drug effects*; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D051379:Mice; D009028:Morula / Q000166:cytology / Q000187:drug effects; D009924:Organ Culture Techniques; D011247:Pregnancy
chemical_list: D000431:Ethanol; D000079:Acetaldehyde