title: Development of a laser balloon for the treatment of gastrointestinal obstruction.
abstract: This work describes the initial results using a laser balloon in a canine model in an attempt to deliver the energy in a circumferential pattern. A balloon catheter, 2 cm long and 3 mm in diameter, was developed. Using a standard cw 100 watt Nd:YAG laser, a 600 micron fiber was tapered to 200 microns and passed through the proximal end of the balloon. Laparotomies were performed on mongrel dogs 14-18 kg in weight. After a gastrotomy, the gastric mucosa was exposed and rugal folds were pulled over the balloon to create a cylinder. Using power settings between 10 and 60 watts, and pulse durations between 10 and 40 seconds, radial energy was delivered and the tissue was examined for both gross and histologic effects. Circumferential zones of coagulation and necrosis were demonstrated.
authors.affiliation: Department of Pathology, Georgetown University School of Medicine, Washington, D.C.
authors.forename: D
authors.initials: D
authors.lastname: Fleischer
authors.forename: E
authors.initials: E
authors.lastname: Cattau
authors.forename: E
authors.initials: E
authors.lastname: Sinofky
authors.forename: J
authors.initials: J
authors.lastname: Newsome
authors.forename: E
authors.initials: E
authors.lastname: Lack
authors.forename: A
authors.initials: A
authors.lastname: Andriuk
authors.forename: S
authors.initials: S
authors.lastname: Benjamin
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D005753:Gastric Mucosa / Q000473:pathology; D005770:Gastrointestinal Neoplasms / Q000150:complications / Q000601:surgery*; D007415:Intestinal Obstruction / Q000209:etiology / Q000601:surgery*; D053685:Laser Therapy / Q000295:instrumentation*; D013270:Stomach / Q000473:pathology