title: [The role of intracellular pool of polyamines in the regulation of metabolism in Escherichia coli during aerobic-anaerobic transitions].
abstract: The transition from aerobic to anaerobic conditions of Escherichia coli cultivation is accompanied by a drop in the free pool of putrescine in the cell as well as in the medium and by a decrease in the intracellular concentration of spermidine. This process stems from at least two facts: (1) the activity of ornithine decarboxylase, a key enzyme in the synthesis of polyamines, falls down due to a decrease in the level of ATP in the cell; (2) the free pool of polyamines is bound to cell compartments, in particular, to nucleoid DNA. The results make it possible to consider the system of polyamine synthesis as a point in the regulatory interaction between the energetic and constructive types of E. coli metabolism.
authors.forename: A G
authors.initials: AG
authors.lastname: Tkachenko
authors.forename: A A
authors.initials: AA
authors.lastname: Chudinov
authors.forename: N S
authors.initials: NS
authors.lastname: Churilova
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D000332:Aerobiosis; D000693:Anaerobiosis; D015317:Biogenic Polyamines / Q000378:metabolism*; D004926:Escherichia coli / Q000201:enzymology / Q000378:metabolism* / Q000648:ultrastructure; D008854:Microscopy, Electron; D009955:Ornithine Decarboxylase / Q000378:metabolism
chemical_list: D015317:Biogenic Polyamines; D000255:Adenosine Triphosphate; D009955:Ornithine Decarboxylase
vernacular_title: Rol' vnutrikletochnogo pula poliaminov v reguliatsii konstruktivnogo obmena Escherichia coli v protsesse aérobno-anaérobnykh perekhodov.