title: Filariasis control in rural areas through detection and treatment with diethylcarbamazine.
abstract: A pilot study for control of bancroftian filariasis through detection and treatment of microfilaria (mf) carriers and filaria disease cases with Diethylcarbamazine (DEC) undertaken in the rural areas of Srikakulam and Vizianagaram of Andhra Pradesh showed that this chemotherapeutic method of control of filaria in rural areas is feasible and acceptable to society. During first round of detection and treatment 20,300 mf carriers (90.6 per cent of detected) and 6,588 disease persons (86 per cent of detected) in Srikakulam and 7,097 mf carriers (94.8 per cent of detected) and 1,436 disease persons (93.4 per cent of detected) in Vizianagaram were treated with DEC tablets. These areas were again surveyed after five years and detected cases were treated with DEC with coverage of treatment ranging from 82.3 per cent to 95 per cent for both mf & disease cases and decline in mf and disease rate was noted to be 52.4 per cent and 50.9 per cent respectively in Srikakulam and 42.2 per cent for mf rate in Vizianagaram. The mf reduction was appreciably high (50 per cent or more) in 11 PHCs of Srikakulam and 4 PHCs of Vizianagaram. The mf rate reduction was the highest in the age group of 1 to 4 year indicating that the transmission has been cut down significantly. The vector infection rate showed reduction by 50 per cent during second round of detection and treatment as compared to first round, indicating significant reduction in transmission potential.
authors.forename: H
authors.initials: H
authors.lastname: Biswas
authors.forename: S P
authors.initials: SP
authors.lastname: Sharma
authors.forename: M
authors.initials: M
authors.lastname: Das
authors.forename: V G
authors.initials: VG
authors.lastname: Rao
authors.forename: R L
authors.initials: RL
authors.lastname: Yadava
authors.forename: M V
authors.initials: MV
authors.lastname: Narasimham
mesh_terms: D000818:Animals; D004049:Diethylcarbamazine / Q000627:therapeutic use*; D004605:Elephantiasis, Filarial / Q000517:prevention & control*; D005368:Filariasis / Q000517:prevention & control*; D006801:Humans; D007194:India; D008842:Microfilariae / Q000302:isolation & purification; D012423:Rural Health; D014958:Wuchereria bancrofti
chemical_list: D004049:Diethylcarbamazine