title: Ultrastructural changes induced by hyperthermia in Chinese hamster V79 fibroblasts.
abstract: The effects of hyperthermic treatment on some intracellular components and on the general morphology of Chinese hamster V79 fibroblasts have been studied. After 1 h of heating at 42 degrees C cells show small interruptions of the plasma membrane, dilation of the mitochondrial cristae and dissociation of the polyribosomes. These modifications become progressively more pronounced after 1 or 3 h treatment at 43 degrees C. Severe alterations in the general morphology of the cells are evident after 1 h heating at 45 degrees C.
authors.affiliation: Laboratory of Ultrastructures, Istituto Superiore di Sanità, Rome, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Arancia
authors.forename: P
authors.initials: P
authors.lastname: Crateri Trovalusci
authors.forename: G
authors.initials: G
authors.lastname: Mariutti
authors.forename: B
authors.initials: B
authors.lastname: Mondovì
mesh_terms: D000818:Animals; D002460:Cell Line; D002462:Cell Membrane / Q000648:ultrastructure; D006224:Cricetinae; D003412:Cricetulus; D005347:Fibroblasts / Q000648:ultrastructure*; D006358:Hot Temperature; D008854:Microscopy, Electron; D008928:Mitochondria / Q000648:ultrastructure; D012270:Ribosomes / Q000648:ultrastructure