title: Regional cerebral blood flow and anxiety: a correlation study in neurologically normal patients.
abstract: Regional CBF (rCBF) was evaluated by the 133Xe inhalation method in 60 neurologically normal patients (30 men and 30 women) and hemispheric and regional values were correlated with anxiety measurements collected by a self-rating questionnaire before and after the examination. Statistically significant negative correlations between rCBF and anxiety measures were found. rCBF reduction for high anxiety levels is in line with results previously reported by others and could be related to lower performance levels for moderately high anxiety scores as those reported in the present population. This could perhaps be explained by rearrangement of flow from cortical zones to deeper areas of the brain, classically known to be implicated in the control of emotions. However, these results should be interpreted cautiously, since they were obtained in patients and not in normal subjects.
authors.affiliation: Institute of Neurophysiopathology, University of Genova, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Rodriguez
authors.forename: P
authors.initials: P
authors.lastname: Cogorno
authors.forename: A
authors.initials: A
authors.lastname: Gris
authors.forename: S
authors.initials: S
authors.lastname: Marenco
authors.forename: C
authors.initials: C
authors.lastname: Mesiti
authors.forename: F
authors.initials: F
authors.lastname: Nobili
authors.forename: G
authors.initials: G
authors.lastname: Rosadini
mesh_terms: D000328:Adult; D000368:Aged; D001007:Anxiety / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D005260:Female; D005625:Frontal Lobe / Q000098:blood supply; D006801:Humans; D008297:Male; D008875:Middle Aged; D009778:Occipital Lobe / Q000098:blood supply; D010296:Parietal Lobe / Q000098:blood supply; D012044:Regression Analysis; D011795:Surveys and Questionnaires; D013702:Temporal Lobe / Q000098:blood supply; D014980:Xenon Radioisotopes
chemical_list: D014980:Xenon Radioisotopes