Water suppression with B0 field gradient homospoil pulses in high-resolution NMR spectroscopy.
The combination of a frequency nonselective excitation suppression method (1331 sequence) with selective excitation followed by gradient-induced dephasing of water transverse magnetization yielded suppression ratios of greater than 10,000:1. The need for gradient preemphasis and correction of B0 field shifts is discussed. The suppression efficiency of this method compared favorably to results obtained using the CPMG spin-echo technique to observe metabolite resonances in a urine sample.
Brereton
I M
IM
Department of Chemistry, University of Queensland, St. Lucia, Australia.
Field
J
J
Moxon
L N
LN
Irving
M G
MG
Doddrell
D M
DM
D004867:Equipment Design; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation / Q000379:methods*; D014556:Urine / Q000032:analysis; D014867:Water
D014867:Water