[Influence of the autonomic nervous system on the diameter and compliance of the brachial artery in normotensive subjects and hypertensive patients].
Studies based on non-invasive methods, using a pulsed Doppler flowmeter technique, show that, in hypertensive patients, the brachial artery reacts actively to posture changes and to a norepinephrin perfusion: in the latter situation, there is an abnormal constriction, and its vasodilation is more marked when the lower extremities are raised in a patient in decubitus. These modifications occur in the absence of any significant variation of the blood pressure and the heart rate, and the high output resulting from the vasodilation is not sufficient to explain these changes. According to the authors, the brachial artery reacts actively to alterations of the autonomous nervous system. Variation observed following elevation of the lower extremities would probably result from the stimulation of the mechanical receptors of a low pressure system.
London
G M
GM
Centre de Diagnostic, Hôpital Broussais, Paris.
Lacolley
P A
PA
Bilhaud
E
E
Laurent
S
S
Safar
M E
ME
D001341:Autonomic Nervous System / Q000187:drug effects*; D001916:Brachial Artery / Q000502:physiology / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology*; D009638:Norepinephrine / Q000494:pharmacology*; D011187:Posture; D014463:Ultrasonography; D014655:Vascular Resistance / Q000187:drug effects / Q000502:physiology
D009638:Norepinephrine
Influence du système nerveux autonome sur le diamètre et la compliance de l'artère humérale chez des sujets normotendus et des patients hypertendus.