Squamous-cell carcinoma and lobomycosis (Jorge Lobo's disease).
Among the Cayabi Indians in Central Brazil, we found a high and unexpected prevalence of lobomycosis, which represents 21% of all the cases reported in the world medical literature until now. Most of the Cayabi patients have been observed for many years, and recently two developed cauliflower-like tumours in old lobomycosis scar lesions. The diagnosis of squamous cell carcinoma was confirmed histologically. In both cases, the tumor was surgically removed, but several months later tumors recurred in both patients. The appearance of squamous cell carcinoma in chronic scar lesions and ulcers of various etiologies has been reported by many authors, and should include lobomycosis.
Baruzzi
R G
RG
Division of Epidemiology, São Paulo Medical School, Brazil.
Rodrigues
D A
DA
Michalany
N S
NS
Salomão
R
R
D001938:Brazil; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007199:Indians, South American; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010229:Paracoccidioidomycosis / Q000150:complications* / Q000453:epidemiology; D012878:Skin Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery