[Gingival hyperplasia in renal transplants treated with cyclosporin].
Cyclosporine is a Metabolita produced by the Topocladium inflamatum fungus. This substance produces an immunosuppression of the selective type, which has been responsible for the increased use of this drug for immunological caused pathologies, especially in organ transplants to inhibit body rejection. One of its secondary characteristics or effects is gingival hyperplasia (in 30 por 100 of the cases noted) an effect which generally occurs on the level or in the area of the dental papilla. An anatomopathological study of these tissues shows an increase in collagens along with a large infiltration of plasmatic cells in different states of maturity. In this article, two cases of renal transplants using cyclosporine were monitored to evaluate its effect in any on the gingival tissues.
Tejerina Lobo
J M
JM
Gomez Huertas
E
E
Mencia Fernandez
C
C
Sampedro Nuño
A
A
Martos Holino
F
F
Lopez Alba
A
A
Santamaria Zuazua
J
J
D000328:Adult; D003524:Cyclosporins / Q000009:adverse effects*; D005885:Gingival Hyperplasia / Q000139:chemically induced*; D006801:Humans; D016030:Kidney Transplantation; D008297:Male
D003524:Cyclosporins
Agrandamiento gingival en trasplantados renales tratados con ciclosporinas.