Rhythms in the ovulatory cycle. 1st: Prolactin. Chronobiological Research Group on Synthetic Peptides in Medicine.
Circadian and circatrigintan profiles of prolactin (PRL) in young normally cycling women at 4 well characterized times of the ovulatory cycle have been compared. Circadian patterns of PRL (collected at 2-h intervals for 24h at each phase selected) change during the 4 phases, being higher in the luteal phase. In a consistent percentage of individuals, serum PRL rises notably during the night; in one half of the subjects a peak is located also in the afternoon or early evening. The statistically significant circatrigintan rhythm of PRL shows the acrophase approximately in the mid-luteal phase.
Carandente
F
F
Cattedra di Cronobiologia, Facoltà di Medicina e Chirurgia, Università degli Studi di Milano, Italy.
Angeli
A
A
Candiani
G B
GB
Crosignani
P G
PG
Dammacco
F
F
De Cecco
L
L
Marrama
P
P
Massobrio
M
M
Martini
L
L
D000328:Adult; D002940:Circadian Rhythm; D005260:Female; D006801:Humans; D008597:Menstrual Cycle; D010060:Ovulation; D010507:Periodicity; D011388:Prolactin / Q000097:blood*
D011388:Prolactin