Comparison between measurements of maternal placental blood flow with dynamic placental scintigraphy and radioactive microspheres.
Two methods for measurements of maternal placental blood flow were compared, dynamic placental scintigraphy using 113mIndium and the radioactive microsphere distribution technique which was the reference method. These methods were both used before and after the blood flow was altered by a noradrenaline infusion in pregnant monkeys (Macaca fascicularis). The change of the blood flow values obtained by the two methods were compared. A statistically significant correlation between the two methods was found (r = 0.90, p less than 0.01). It is concluded that dynamic placental scintigraphy can be used as a technique for clinical measurements of relative changes of the maternal placental blood flow.
Skjöldebrand
A
A
Department of Anaesthesiology, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden.
Jansson
T
T
Kjellmer
I
I
Lunell
N
N
Nylund
L
L
Sarby
B
B
Thornström
S
S
D000818:Animals; D002565:Cerium Radioisotopes; D005260:Female; D007205:Indium Radioisotopes; D008252:Macaca fascicularis; D008863:Microspheres; D009556:Niobium; D010920:Placenta / Q000098:blood supply* / Q000000981:diagnostic imaging; D011247:Pregnancy; D011868:Radioisotopes; D011877:Radionuclide Imaging; D012039:Regional Blood Flow; D012429:Ruthenium Radioisotopes
D002565:Cerium Radioisotopes; D007205:Indium Radioisotopes; D011868:Radioisotopes; D012429:Ruthenium Radioisotopes; D009556:Niobium