Intravascular lipoleiomyomatosis: a report of two cases.
Two cases of intravascular leiomyomatosis (IVL) with histologic features of a lipoleiomyoma (LPL) are reported. Both tumors arose from preexisting uterine leiomyomata. One tumor was found incidentally in a uterus removed for leiomyomata. The other tumor extended up the inferior vena cava into the right side of the heart and presented as a cardiac mass. Although LPL is considered to be a benign lesion, IVL recurs in approximately 10% of reported cases, and must be distinguished from low-grade endometrial stromal sarcoma and leiomyosarcoma with vascular invasion. The combination of features in these cases lends support to the theory that IVL may arise by intravascular extension of a preexisting leiomyoma.
Brescia
R J
RJ
Department of Pathology, Rush-Presbyterian-St Luke's Medical Center, Chicago.
Tazelaar
H D
HD
Hobbs
J
J
Miller
A W
AW
D000328:Adult; D005187:Fallopian Tubes / Q000473:pathology; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000473:pathology*; D008875:Middle Aged; D014594:Uterine Neoplasms / Q000473:pathology*; D014599:Uterus / Q000473:pathology