[Changes in the blood coagulation potential of premature calves with and without respiratory distress syndrome].
In 46 newborn calves with and without respiratory distress syndrome which had been delivered prematurely by caesarean section a blood coagulation profile was established. These animals were compared with 26 healthy, 5- to 8-day-old calves. Prematurely delivered calves showed a lower average plasma fibrinogen concentration than animals delivered in due time. Calves which developed a respiratory distress syndrome had a slightly prolonged prothrombin time and partial thromboplastin time as well as a lower antithrombin III activity already immediately postnatum compared with healthy prematures and some-day-old calves. It has to be assumed that in calves with respiratory distress syndrome--in analogy to pulmonary immaturity--the blood clotting mechanism is not yet fully developed. In healthy prematures and surviving asphyctic calves hemostasis remains largely stable during the first day of life, whereas plasma fibrinogen concentration increases. In the calves not surviving the examination period prothrombin time and partial thromboplastin time postnatum became significantly longer. Only in these severely asphyctic calves the presence of a consumption coagulopathy seems likely. A secondary reactive fibrinolysis was not observed.
Aurich
J E
JE
Klinik für Geburtshilfe und Gynäkologie des Rindes der Tierärztlichen Hochschule Hannover.
Grunert
E
E
Zaremba
W
W
D000818:Animals; D000831:Animals, Newborn; D000990:Antithrombin III / Q000032:analysis; D001777:Blood Coagulation; D002417:Cattle; D002418:Cattle Diseases / Q000097:blood*; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn; D010314:Partial Thromboplastin Time / Q000662:veterinary; D011517:Prothrombin Time / Q000662:veterinary; D012127:Respiratory Distress Syndrome, Newborn / Q000097:blood / Q000662:veterinary*
D000990:Antithrombin III; D005340:Fibrinogen
Veränderungen im Blutgerinnungspotential frühgeborener Kälber mit und ohne Atemnotsyndrom.