1H spectroscopic imaging at high spatial resolution.
Spectroscopic imaging and single voxel localization are compared with respect to the signal to noise ratio per unit time and unit volume. It is shown experimentally that, when using the same experiment time and the same voxel size, both methods give similar results. In order to investigate the localization limits of spectroscopic imaging, lipid distribution in a single large cell was measured and correlated with gradient echo microscopy.
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NMR Unit, Medical Faculty, University of Berne, Switzerland.
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D000818:Animals; D007091:Image Processing, Computer-Assisted; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008961:Models, Structural; D009865:Oocytes / Q000166:cytology; D014982:Xenopus laevis