[Antifungal effects in vitro of jasmon and some similar compounds. Structure-activity relationship].
The antimycotic activity in vitro of jasmon and 6 closely related substances has been tested against four different dermatophytes, Candida albicans, Pityrosporum ovale and Aspergillus fumigatus. Jasmon had the highest activity. Among the other substances tested only thiazolidines with a carbonyl function developed antifungal properties against dermatophytes. 2,4 thiazolidinedione at 450 ppm inhibits the growth of Trichophyton rubrum.
Millet-Clerc
J
J
Michel
D
D
Chaumont
J P
JP
D000935:Antifungal Agents / Q000494:pharmacology*; D001232:Aspergillus fumigatus / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D066298:In Vitro Techniques; D008290:Malassezia / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D008864:Microsporum / Q000187:drug effects; D010946:Plants, Medicinal / Q000032:analysis; D013329:Structure-Activity Relationship; D014249:Trichophyton / Q000187:drug effects
D000935:Antifungal Agents
Effects antifongiques in vitro de la jasmone et de quelques composés voisins. Relation structure-activité.