[Granulomatous hepatitis secondary to ingestion of carbamazepine. Report of a case].
A 51-year-old man with epilepsy received carbamazepine during three weeks. He developed fever, jaundice, dark urine and pale stools. Laboratory data showed hepatocellular injury and cholestasis; six weeks after withdrawal of the drug these abnormalities returned to normal limits. The liver biopsy showed acute cholangitis, bile duct injury, granulomas and eosinophils in the portal areas.
Rodríguez Hernández
H
H
Dehesa Violante
M
M
Vega Ramos
B
B
Méndez Gutiérrez
T H
TH
D002220:Carbamazepine / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000473:pathology; D004833:Epilepsy, Temporal Lobe / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged
D002220:Carbamazepine
Hepatitis granulomatosa secundaria a la ingestión de carbamazepina. Informe de un caso.