A hereditary double double-banded variation in the vitamin D-binding protein (GC) system analyzed by immunoblotting: duplication of the 1F and 1A2 genes?
A combination of immunoblotting and polyacrylamide gel isoelectric focusing (IEF-PAGE) was used to define a new genetic variant in the (GC) group-specific component system. This appeared to be a GC 1-type variant, and was presumed to have arisen from duplication of the GC 1F and GC 1A2 genes.
Yasuda
T
T
Department of Legal Medicine, Fukui Medical School, Japan.
Ikehara
Y
Y
Takagi
S
S
Mizuta
K
K
Kishi
K
K
D015153:Blotting, Western; D014644:Genetic Variation; D006801:Humans; D007526:Isoelectric Point; D007564:Japan; D005810:Multigene Family; D010375:Pedigree; D014809:Vitamin D-Binding Protein / Q000235:genetics*
D014809:Vitamin D-Binding Protein