Value of screening umbilical cord blood for hemoglobinopathy.
Foremost among the beneficial effects of screening umbilical cord blood is the optimized quality of care that can follow the immediate involvement of an infant with sickle cell disease and his or her family in an appropriate health care system. This is exemplified by the reduction in the case fatality rate of pneumococcal septicemia that has been achieved. Appropriate follow-up of screening also includes transmission of information about the diagnosis of a hemoglobinopathy trait or alpha-thalassemia to affected families and their physicians, with ready availability of education and counseling.
Lobel
J S
JS
Department of Pediatrics, University of Cincinnati, College of Medicine.
Cameron
B F
BF
Johnson
E
E
Smith
D
D
Kalinyak
K
K
D000755:Anemia, Sickle Cell / Q000097:blood* / Q000453:epidemiology / Q000401:mortality; D005312:Fetal Blood / Q000032:analysis*; D006450:Hemoglobin SC Disease / Q000097:blood; D006451:Hemoglobin, Sickle / Q000032:analysis*; D006801:Humans; D007231:Infant, Newborn; D008403:Mass Screening; D009820:Ohio; D012805:Sickle Cell Trait / Q000097:blood; D013789:Thalassemia / Q000097:blood
D006451:Hemoglobin, Sickle