An antifungal constituent from the stem bark of Butea monosperma.
The petroleum and ethyl acetate extracts of the stem bark from Butea monosperma displayed antifungal activity against Cladosporium cladosporioides. The active constituent of low polarity was isolated by bioassay-monitored chromatographic fractionation, and identified as (-)-medicarpin by comparison of physical data. The antifungal activity of (-)-medicarpin was found to be greater than that of Benlate, a standard fungicide, while (-)-medicarpin acetate also exhibited significant activity against C. cladosporiodes.
Bandara
B M
BM
Department of Chemistry, University of Peradeniya, Sri Lanka.
Kumar
N S
NS
Samaranayake
K M
KM
D000085:Acetates; D000935:Antifungal Agents / Q000302:isolation & purification*; D001578:Benzopyrans / Q000302:isolation & purification; D002963:Cladosporium / Q000187:drug effects; D010578:Petroleum; D010946:Plants, Medicinal / Q000032:analysis*; D036343:Pterocarpans; D000094162:Phytoalexins
D000085:Acetates; D000935:Antifungal Agents; D001578:Benzopyrans; D010578:Petroleum; D036343:Pterocarpans; C047353:medicarpin; D000094162:Phytoalexins; C007650:ethyl acetate