title: Biosynthesis of the two halobacterial light sensors P480 and sensory rhodopsin and variation in gain of their signal transduction chains.
abstract: The two retinal-containing photoreceptors of halobacteria, P480 and sensory rhodopsin, are formed constitutively and inducibly, respectively. Both photoreceptors are synthesized as apoproteins in cells with nicotine-inhibited retinal synthesis and are reconstituted as chromoproteins by the addition of all-trans retinal to cell membrane preparations. The decrease in photoreceptor-mediated photophobic response at the stationary growth phase of cells is not due to photoreceptor degradation but due to a deficiency of the signal transduction chain in the cell.
authors.affiliation: Max-Planck-Institut für Biochem e, Martinsried, Federal Republic of Germany.
authors.forename: J
authors.initials: J
authors.lastname: Otomo
authors.forename: W
authors.initials: W
authors.lastname: Marwan
authors.forename: D
authors.initials: D
authors.lastname: Oesterhelt
authors.forename: H
authors.initials: H
authors.lastname: Desel
authors.forename: R
authors.initials: R
authors.lastname: Uhl
mesh_terms: D001426:Bacterial Proteins / Q000096:biosynthesis*; D001436:Bacteriorhodopsins / Q000502:physiology*; D002462:Cell Membrane / Q000502:physiology; D006217:Halobacterium / Q000502:physiology*; D008027:Light; D010786:Photoreceptor Cells / Q000502:physiology*; D012172:Retinaldehyde / Q000378:metabolism; D013057:Spectrum Analysis
chemical_list: D001426:Bacterial Proteins; D001436:Bacteriorhodopsins; D012172:Retinaldehyde