Chromosome abnormalities in a pancreatic adenocarcinoma.
Short-term cultures initiated from a pancreatic adenocarcinoma were cytogenetically investigated. The composite karyotype was 74-76,XX,+X,+2,+3,+del(3)(p21),+5,+5,+der(7) t(1;7)(q21;p22),+der(7),del(8)(p21),+del(8)(p21),+der(8)t(8;?)(q24; +),+9,+9,+10,+10,+11,+11,+12,+13,+14,+der(14)t(14; +)(p11;?),+der(16)t(15;16)(q11;p13),+der(16),+der(17)t(17;?) (p11;?),+der(17),+18,+20,+20,-21,-21,+22,+22,+1-3mar. A comparison with the few previously cytogenetically characterized cases of this tumor type reveals no consistent abnormalities.
Johansson
B
B
Department of Clinical Genetics, University Hospital, Lund, Sweden.
Mandahl
N
N
Heim
S
S
Mertens
F
F
Andrén-Sandberg
A
A
Mitelam
F
F
D000230:Adenocarcinoma / Q000235:genetics*; D000368:Aged; D002869:Chromosome Aberrations; D066246:ErbB Receptors / Q000235:genetics; D005260:Female; D006801:Humans; D007621:Karyotyping; D010190:Pancreatic Neoplasms / Q000235:genetics*
D066246:ErbB Receptors