title: Long QT syndrome associated with inflammatory degeneration of the stellate ganglia.
abstract: A well-studied case of intermittent long QT syndrome in a 21-year-old female is presented. Electrophysiologic investigation repeated three times revealed changing sinoatrial and atrioventricular dysfunction and nonsustained ventricular tachycardia. The patient died 29 months after first hospitalization in a stage of electromechanical dissociation after runs of torsade de pointes although she had been treated with repeated anti-inflammatory therapy as well as high doses of propranolol. Postmortem examination demonstrated active inflammation of stellate ganglia. Myocardium appeared normal.
authors.affiliation: Central Institute for Heart and Circulation Research, Academy of Sciences, Berlin, German Democratic Republic.
authors.forename: D
authors.initials: D
authors.lastname: Pfeiffer
authors.forename: H
authors.initials: H
authors.lastname: Fiehring
authors.forename: H G
authors.initials: HG
authors.lastname: Henkel
authors.forename: K J
authors.initials: KJ
authors.lastname: Rostock
authors.forename: K
authors.initials: K
authors.lastname: Rathgen
mesh_terms: D000328:Adult; D001145:Arrhythmias, Cardiac / Q000473:pathology*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007249:Inflammation / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D008133:Long QT Syndrome / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D011239:Prednisolone / Q000627:therapeutic use; D011433:Propranolol / Q000627:therapeutic use; D013233:Stellate Ganglion / Q000473:pathology*; D013610:Tachycardia / Q000209:etiology
chemical_list: D011239:Prednisolone; D011433:Propranolol