title: [Initial dyscirculatory encephalopathy in middle-aged and elderly patients (problems of early diagnosis and therapy)].
abstract: Combined clinicophysiological investigation was performed in IDE (195 patients) in order to assess the degree of cerebral circulation disorders and their impact on the levels of brain functional activity. The informative values of several quantitative indices of brain hemodynamics and neurodynamics were assessed with respect to the patients' age. Single administration and full course of cavinton and sermion (nicergoline) were effective as judged by cerebral circulation studies (133Xe clearance), brain bioelectric activity (EEG frequency integration analysis, visual evoked potentials). In senile patients, the effect of i.v. sermion administration was dose-dependent.
authors.forename: N B
authors.initials: NB
authors.lastname: Man'kovskiĭ
authors.forename: A Ia
authors.initials: AIa
authors.lastname: Mints
authors.forename: I N
authors.initials: IN
authors.lastname: Karaban'
mesh_terms: D000368:Aged; D002560:Cerebrovascular Circulation / Q000187:drug effects; D002561:Cerebrovascular Disorders / Q000175:diagnosis* / Q000188:drug therapy; D004873:Ergolines / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D009530:Nicergoline / Q000627:therapeutic use*; D013997:Time Factors; D014665:Vasodilator Agents; D014748:Vinca Alkaloids / Q000627:therapeutic use*
chemical_list: D004873:Ergolines; D014665:Vasodilator Agents; D014748:Vinca Alkaloids; C013983:vinpocetine; D009530:Nicergoline
vernacular_title: Nachal'naia distsirkuliatornaia éntsefalopatiia u bol'nykh srednego i pozhilnogo vozrasta (voprosy ranneĭ diagnostiki i terapii).