title: Visual toxicity of synthetic retinoids.
abstract: Twelve patients treated with isotretinoin, a synthetic vitamin A analogue, were assessed before, during, and after therapy. Significant falls occurred in the amplitude of the a waves of the scotopic electroretinogram.
authors.affiliation: Birmingham and Midland Eye Hospital.
authors.forename: R D
authors.initials: RD
authors.lastname: Brown
authors.forename: C E
authors.initials: CE
authors.lastname: Grattan
mesh_terms: D004596:Electroretinography; D006801:Humans; D015474:Isotretinoin / Q000009:adverse effects*; D010865:Pilot Projects; D011446:Prospective Studies; D012160:Retina / Q000187:drug effects* / Q000503:physiopathology
chemical_list: D015474:Isotretinoin