Chromosome 17p loss in carcinoma of the cervix uteri.
Markers derived from chromosome 17 were present in 13 (42%) of 31 carcinomas of the cervix uteri. Altogether, 14 such markers were present, ten of which were 17p+ chromosomes with a small amount of additional material, probably of variable origin, while three were i(17q)s. The significance of the chromosome 17 aberrations in cervical carcinoma may lie in the loss of recessive genes on 17p.
Atkin
N B
NB
Department of Cancer Research, Mount Vernon Hospital, Northwood, Middlesex, England.
Baker
M C
MC
D002277:Carcinoma / Q000235:genetics*; D002869:Chromosome Aberrations; D002886:Chromosomes, Human, Pair 17; D005260:Female; D006801:Humans; D002583:Uterine Cervical Neoplasms / Q000235:genetics*