Kidney transplantation in insulin dependent diabetic patients: improved survival and rehabilitation.
Between 1977 and 1986, 50 insulin-dependent diabetic patients received a kidney transplant, 19 from living related donors and 31 from cadaveric donors. Cumulative patient survival was 81% and graft survival was 64% and 33% for living related and cadaveric donor kidneys, respectively, at five years. These results are comparable to that of nondiabetic patients. While physical performance and visual acuity significantly improved after a successful kidney transplantation, neuropathies and angiopathies might not improve. Physical performance improved even in those patients whose nerve conduction time had deteriorated. These findings suggest that kidney transplantation is an effective means of improving survival and rehabilitation of diabetic patients with end-stage renal disease.
Cheigh
J S
JS
Rogosin Kidney Center, Department of Medicine, New York Hospital/Cornell Medical Center, New York 10021.
Riggio
R R
RR
Stenzel
K H
KH
Green
R
R
Tapia
L
L
Schechter
N
N
Suthamthiran
M
M
Stubenbord
W T
WT
Rubin
A L
AL
Riehle
R A
RA
D000328:Adult; D002102:Cadaver; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000503:physiopathology; D003928:Diabetic Nephropathies / Q000150:complications* / Q000503:physiopathology; D005260:Female; D005500:Follow-Up Studies; D006085:Graft Survival; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000601:surgery*; D008297:Male; D011379:Prognosis; D011446:Prospective Studies; D014019:Tissue Donors