title: [Circadian rhythm of blood acetylcholinesterase after administration of organophosphate compounds during hypokinesia].
abstract: Circadian and ultradian rhythms of blood acetylcholinesterase (ACE) and rectal temperature were investigated during hypokinesia and administration of a toxic organic phosphate compound in various doses. Hypokinesia was found to produce a strong desynchronizing effect on ACE and thermal regulation. It is maintained that the use of chemicals with a well documented mechanism of action may yield reliable information about biorhythm restructuring in response to exogenous effects. It is emphasized that biorhythm changes should be taken into consideration when arranging work schedules in hypokinetic conditions.
authors.forename: B B
authors.initials: BB
authors.lastname: Dobriian
authors.forename: M B
authors.initials: MB
authors.lastname: Shpirt
authors.forename: V Sh
authors.initials: VSh
authors.lastname: Eroshenko
authors.forename: K A
authors.initials: KA
authors.lastname: Abdashimov
mesh_terms: D000110:Acetylcholinesterase / Q000097:blood*; D000279:Administration, Cutaneous; D000818:Animals; D002800:Cholinesterase Inhibitors; D002940:Circadian Rhythm; D007103:Immobilization; D008297:Male; D063086:Organothiophosphates / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000633:toxicity*; D009946:Organothiophosphorus Compounds / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000633:toxicity*; D051381:Rats; D012869:Skin Absorption
chemical_list: D002800:Cholinesterase Inhibitors; D063086:Organothiophosphates; D009946:Organothiophosphorus Compounds; C009532:trichlorometaphos-3; C006863:butyl phosphorotrithioate; D000110:Acetylcholinesterase
vernacular_title: Sutochnaia ritmika atsetilkholinésterazy krovi pri vozdeĭstvii fosfororganicheskogo soedineniia pri gipokinezii.