title: Hepatoprotective effects of Wedelia calendulacea.
abstract: The alcoholic extract of whole plant Wedelia calendulacea exhibited protective activity against carbon tetrachloride-induced liver injury in vivo. The extract also increased the bile flow in rats suggesting a stimulation of liver secretory capacity. The minimum lethal dose was greater than 200 mg/kg p.o. in mice.
authors.affiliation: Regional Research Laboratory, Jammu, India.
authors.forename: A K
authors.initials: AK
authors.lastname: Sharma
authors.forename: K K
authors.initials: KK
authors.lastname: Anand
authors.forename: P
authors.initials: P
authors.lastname: Pushpangadan
authors.forename: B K
authors.initials: BK
authors.lastname: Chandan
authors.forename: C L
authors.initials: CL
authors.lastname: Chopra
authors.forename: Y S
authors.initials: YS
authors.lastname: Prabhakar
authors.forename: N P
authors.initials: NP
authors.lastname: Damodaran
mesh_terms: D000818:Animals; D001646:Bile / Q000187:drug effects / Q000378:metabolism; D002251:Carbon Tetrachloride / Q000037:antagonists & inhibitors / Q000633:toxicity; D006591:Hexobarbital / Q000037:antagonists & inhibitors / Q000633:toxicity; D007194:India; D008099:Liver / Q000187:drug effects* / Q000293:injuries; D008297:Male; D008657:Metabolic Clearance Rate / Q000187:drug effects; D051379:Mice; D010946:Plants, Medicinal; D011517:Prothrombin Time; D051381:Rats; D012018:Reflex / Q000187:drug effects; D013448:Sulfobromophthalein / Q000493:pharmacokinetics
chemical_list: D013448:Sulfobromophthalein; D006591:Hexobarbital; D002251:Carbon Tetrachloride