[Effectiveness of a topical medical treatment following diathermic coagulation: controlled clinical study].
A controlled clinical study has been conducted on the efficacy of a topic therapy. Kanamicine sulphate daily for 6 days and altered to polidesossiribonucleotide for the following 24 days were given after cervical cauterization for ectropion with or without AnTZ. Treated patients were 148 and untreated ones were 155. Subjective and objective parameters were evaluated. Among the former only bloody discharge (more frequent among the treated patients) and ill-smelling discharge (more frequent among the untreated patients) showed significant differences. Colposcopy instead showed better (or faster) healing of the treated group, with 83.6% vs 62% iodine dark cervices at Schiller test and 87.9% vs 59.7% SCJ at the external os or inside (P less than 0.01). Also disepitelized areas or areas with frail epithelium were less common among the treated patients.
Bianco
V
V
Stillo
A
A
Vassalli
S B
SB
D000287:Administration, Topical; D004359:Drug Therapy, Combination; D004483:Ectropion / Q000601:surgery; D004564:Electrocoagulation / Q000009:adverse effects; D005260:Female; D006801:Humans; D007612:Kanamycin / Q000008:administration & dosage / Q000627:therapeutic use; D011089:Polydeoxyribonucleotides / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D016032:Randomized Controlled Trials as Topic; D002577:Uterine Cervical Diseases / Q000601:surgery; D014945:Wound Healing / Q000187:drug effects
D011089:Polydeoxyribonucleotides; D007612:Kanamycin
Efficacia della terapia medica topica post-DTC: studio clinico controllato.