Evaluation method for krypton-81m reservoir administration systems.
Large variations have been reported in counting rates during lung ventilation studies using different 81mKr administration systems and among different patients. A method was set up to determine the activity utilization efficiency (AUE) using various administration systems. For that purpose a simple lung simulator was developed for combination with reservoir administration systems to be tested. It was found that under normal breathing conditions the AUE is 50% using a reservoir system and only 18% in the absence of a reservoir in the administration system. The measured results were confirmed by a mathematic model. The suggested simulator is suitable for use in hospitals and also enables an indirect check on the 81Rb/81mKr generator performance.
Janssen
A G
AG
Department of Physics, Eindhoven University of Technology, The Netherlands.
van Weeren
F H
FH
de Goeij
J J
JJ
Wijnhoven
G P
GP
Witsenboer
T J
TJ
D004867:Equipment Design; D005069:Evaluation Studies as Topic; D006207:Half-Life; D006801:Humans; D007727:Krypton Radioisotopes / Q000008:administration & dosage*; D008168:Lung / Q000000981:diagnostic imaging; D008433:Mathematics; D008954:Models, Biological; D008961:Models, Structural; D011876:Radionuclide Generators / Q000295:instrumentation*; D011877:Radionuclide Imaging; D012119:Respiration
D007727:Krypton Radioisotopes