Reaction of 3-dehydroecdysone with certain n.m.r. solvents.
Synthetically prepared 3-dehydroecdysone shows by n.m.r. spectroscopy a mixture of two and three components in 2H2O and [2H4]methanol respectively; only 3-dehydroecdysone is indicated in [2H5]pyridine. Although 3-dehydroecdysone is the sole component in [2H5]pyridine, it represents only 62% and 55% in 2H2O and [2H4]methanol respectively. Evidence indicates that the other component in 2H2O is a 3-[2H2]hydrate of 3-dehydroecdysone, and that in [2H4]methanol the other two components are isomeric [2H3]hemiacetals of 3-dehydroecdysone.
Howarth
O W
OW
Department of Chemistry, University of Warwick, Coventry, U.K.
Thompson
M J
MJ
Rees
H H
HH
D004440:Ecdysone / Q000031:analogs & derivatives* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D000432:Methanol; D011725:Pyridines; D012997:Solvents; D014867:Water
D011725:Pyridines; D012997:Solvents; D014867:Water; D004440:Ecdysone; C047104:3-dehydroecdysone; D000432:Methanol