Morphometric study of stratum corneum in leprosy.
Abnormalities in Stratum Corneum (SC) in leprosy lesions have been demonstrated as evidenced by poor hydration power of SC and increased SC turn-over. In continuation of the same study morphometric studies of the SC in leprosy was undertaken as per measurement of the Thickening of the SC, Mean epidermal thickness and Basal layer: Granular layer cell ratio (B : G ratio) of the H.E. stained tissues. Further, on freshly frozen tissues the SC cell-layers were also counted. The findings suggest increased proliferative activity of the epidermis which may lead to formation of defective SC in leprosy.
Okhandiar
R P
RP
Skin and Leprosy Research Foundation, Kharman Chak, Bhagalpur, Bihar.
Sinha
E
E
Sinha
R K
RK
Mishra
A D
AD
D000293:Adolescent; D000328:Adult; D002455:Cell Division; D004817:Epidermis / Q000473:pathology*; D006801:Humans; D015439:Leprosy, Borderline / Q000473:pathology*; D015441:Leprosy, Tuberculoid / Q000473:pathology*; D008297:Male; D008875:Middle Aged