title: [Danol (danazol) in the treatment of fibrocystic breast disease with mastodynia].
abstract: The author investigated in a group of 12 premenopausal women with fibrocystic mastopathy with mastodynia, confirmed on mammography, the effectiveness of a synthetic ethisterone derivative--danazole. An objective effect (reduction of the number and/or diminution of nodularities in the mammary parenchyma) was achieved in 67%, disappearance of mastodynia in 100%. As to side-effects only amenorrhoea was observed in 92%, spotting in 8%, an increase of body weight (1-6 kg) in 83% of the treated women. Danol will, with regard to its effectiveness and very good tolerance, if more widely available, substantially extend our therapeutic possibilities in the above indication.
authors.forename: I
authors.initials: I
authors.lastname: Lorenz
mesh_terms: D000328:Adult; D003613:Danazol / Q000627:therapeutic use*; D005260:Female; D005348:Fibrocystic Breast Disease / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D010146:Pain; D011245:Pregnadienes / Q000627:therapeutic use*
chemical_list: D011245:Pregnadienes; D003613:Danazol
vernacular_title: Danol (danazol) v lécbĕ fibrocystické mastopatie s mastodyniemi.