Fatal fungal peritonitis in an adolescent on continuous ambulatory peritoneal dialysis: association with deferoxamine.
An unusual case of Rhizopus microsporus (mucormycosis) fungal infection in a teenage boy on continuous ambulatory peritoneal dialysis is presented. Premortem cultures were negative and the patient developed a rapidly disseminated fatal infection. The patient was being treated with deferoxamine (DFO) for iron and aluminum overload. An argument is made for a probable association between DFO and this fatal fungal infection in patients with end-stage renal disease.
Nakamura
M
M
Michigan State University, East Lansing 48824-1317.
Weil
W B
WB
Kaufman
D B
DB
D000293:Adolescent; D003676:Deferoxamine / Q000009:adverse effects*; D015433:Glomerulonephritis, Membranous / Q000150:complications; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000628:therapy; D008297:Male; D009091:Mucormycosis / Q000209:etiology*; D010531:Peritoneal Dialysis, Continuous Ambulatory; D010538:Peritonitis / Q000209:etiology*; D006435:Renal Dialysis; D012233:Rhizopus
D003676:Deferoxamine