[Farmer's lung: IgG-subclass reactivities against thermophilic actinomycetes].
IgG subclass reactivities of patients suffering from farmer's lung, healthy family members and blood donors were tested for specific binding to Micropolyspora faeni extract by means of immunoblot techniques (IEF-Print, Western Blot). In patients' sera IgG1 and IgG2 had shown the strongest reactivities while IgG3- and IgG4-reactivities were not found in all cases. Strong IgG2-reactivities against acidic proteins (pl 3-5) of M. faeni seem to distinguish between patients and exposed or not exposed controls, respectively.
Reese
G
G
Forschungsinstitut Borstel, Medizinische Klinik.
Becker
W M
WM
Schlaak
M
M
D015153:Blotting, Western; D005203:Farmer's Lung / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis / Q000145:classification / Q000276:immunology*; D007525:Isoelectric Focusing; D008848:Micromonosporaceae / Q000276:immunology*
D007074:Immunoglobulin G
Farmerlunge: IgG-Subklassenreaktivitäten gegen thermophile Aktinomyzeten.