title: [Intraoperative radiotherapy in locally advanced carcinoma of the kidney: initial experience].
abstract: Intraoperative radiotherapy (IORT) is a rather interesting therapeutic modality in multidisciplinary oncology. Its greatest advantages reside in the approach of deeply seeded abdomino-pelvic tumors. Its inclusion in the therapeutic approach of renal carcinoma with a high local relapse rate has been analyzed in this study in relation to its technical aspects and preliminary clinical results. 11 stage III or IV patients or with local relapse in lumbar fossa were treated with nephrectomy or exeresis surgery and OIRT (10-20 Gy). Surgical exposure of the lumbar fossa and nodal drainage areas was appropriate in dal cases. No toxic signs or sequellae relating to OIRT were observed. Local tumor controls at 8 months of follow-up on the average (range from 2 to 33 months), was 82%. The data obtained in this series suggest the viability of the combined approach nephrectomy or rescue surgery and IORT. The initial clinical results suggest HIGH local tumor control without an increase in the toxicity rate or complications.
authors.forename: M
authors.initials: M
authors.lastname: Santos
authors.forename: A
authors.initials: A
authors.lastname: Ucar
authors.forename: H
authors.initials: H
authors.lastname: Ramos
authors.forename: L
authors.initials: L
authors.lastname: Escudé
authors.forename: J M
authors.initials: JM
authors.lastname: Berian
authors.forename: J
authors.initials: J
authors.lastname: Zudaire
authors.forename: F A
authors.initials: FA
authors.lastname: Calvo
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000532:radiotherapy* / Q000601:surgery; D000328:Adult; D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D007680:Kidney Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods; D010865:Pilot Projects; D011879:Radiotherapy Dosage
vernacular_title: Radioterapia intraoperatoria en el carcinoma renal localmente avanzado: experiencia inicial.