title: Video fluorescein angiography: method and clinical application.
abstract: Video fluorescein angiography, combined with a picture analyzing system, is a clinically applicable, objective method of evaluating the retinal blood-flow parameters. Optical density measurements were performed on videorecordings of fluorescence angiograms by means of a picture-analyzing system in order to determine the circulation parameters of the retina. These included: the arm-retina time (ART), the arteriovenous passage time (AVP), and the mean arterial dye-bolus velocity (MDV). Normal values for these parameters were derived from measurements in 75 healthy volunteers. The mean arm-retina time (ART) was 11.2 +/- 3.3 s, the mean arteriovenous passage time (AVP) 1.45 +/- 0.4 s and the mean arterial dye-bolus velocity (MDV) 6.39 +/- 1.7 mm/s. No significant correlation could be shown between pulse or blood pressure and one of the retinal circulation parameters. A group of ten healthy volunteers was examined twice in order to obtain the intraindividual variation for the measuring parameters. The coefficient of variation for the ART was 18%, 10% for the AVP, and 26% for the MDV.
authors.affiliation: Augenklinik der Rheinisch-Westfälischen Technischen Hochschule, Aachen, Federal Republic of Germany.
authors.forename: S
authors.initials: S
authors.lastname: Wolf
authors.forename: F
authors.initials: F
authors.lastname: Jung
authors.forename: H
authors.initials: H
authors.lastname: Kiesewetter
authors.forename: N
authors.initials: N
authors.lastname: Körber
authors.forename: M
authors.initials: M
authors.lastname: Reim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012171:Retinal Vessels / Q000502:physiology*; D013997:Time Factors; D014741:Video Recording