Effects of ultrasound on ovulation in the mouse.
In vitro fertilization and embryo transfer (IVF-ET) programs use ultrasound extensively for monitoring the growth of ovarian follicles and, subsequently, for confirming the presence of a fetal sac. There have been few reports of the effects of ultrasound on ovulation rates in mammals, and we report here that following exposure to continuous wave ultrasound at a spatial average intensity of 3.0 W/cm2 for five minutes, ovulation rates measured 10 days later were significantly reduced in mice. When temperature elevation of the exposed ovary was measured with a thermocouple, hyperthermia correlated with reduction in ovulation.
Heyner
S
S
Department of Obstetrics and Gynecology, Albert Einstein Medical Center, Philadelphia, PA 19141.
Abraham
V
V
Wikarczuk
M L
ML
Ziskin
M C
MC
D000818:Animals; D002452:Cell Count; D005260:Female; D051379:Mice; D009865:Oocytes / Q000166:cytology; D010060:Ovulation; D013223:Statistics as Topic; D014465:Ultrasonics