Video fluorescein angiography: method and clinical application.
Video fluorescein angiography, combined with a picture analyzing system, is a clinically applicable, objective method of evaluating the retinal blood-flow parameters. Optical density measurements were performed on videorecordings of fluorescence angiograms by means of a picture-analyzing system in order to determine the circulation parameters of the retina. These included: the arm-retina time (ART), the arteriovenous passage time (AVP), and the mean arterial dye-bolus velocity (MDV). Normal values for these parameters were derived from measurements in 75 healthy volunteers. The mean arm-retina time (ART) was 11.2 +/- 3.3 s, the mean arteriovenous passage time (AVP) 1.45 +/- 0.4 s and the mean arterial dye-bolus velocity (MDV) 6.39 +/- 1.7 mm/s. No significant correlation could be shown between pulse or blood pressure and one of the retinal circulation parameters. A group of ten healthy volunteers was examined twice in order to obtain the intraindividual variation for the measuring parameters. The coefficient of variation for the ART was 18%, 10% for the AVP, and 26% for the MDV.
Wolf
S
S
Augenklinik der Rheinisch-Westfälischen Technischen Hochschule, Aachen, Federal Republic of Germany.
Jung
F
F
Kiesewetter
H
H
Körber
N
N
Reim
M
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012171:Retinal Vessels / Q000502:physiology*; D013997:Time Factors; D014741:Video Recording