Koelliker haemoglobins in developing chick embryo.
1. Three Koelliker haemoglobins, HbKE, HbKA and HbKH, derived from a post-translational loss of alpha-Arg-141, were isolated from red cells of chicken embryos. HbKE is typical of embryos up to 7 days of incubation, HbKA and HbKH are found in mature embryos. 2. All the precursor haemoglobins contain alpha A chains. HbKA derives from adult haemoglobin A whose globin composition is alpha A2 beta 2, HbKH from embryonic haemoglobin H with a globin composition alpha A2 beta H2 and HbKE from embryonic haemoglobin E with globin composition alpha A2 epsilon 2. 3. No Koelliker derivatives of haemoglobins with alpha-like chains other than alpha A were observed.
Cirotto
C
C
Istituto di Biologia Cellulare, Universitá Perugia, Italy.
Arangi
I
I
D000818:Animals; D002266:Carboxymethylcellulose Sodium; D002642:Chick Embryo / Q000032:analysis* / Q000254:growth & development; D002845:Chromatography; D004591:Electrophoresis, Polyacrylamide Gel; D005914:Globins / Q000302:isolation & purification; D006455:Hemoglobins, Abnormal / Q000302:isolation & purification*; D011499:Protein Processing, Post-Translational
D006455:Hemoglobins, Abnormal; C034535:hemoglobin Koelliker; D005914:Globins; D002266:Carboxymethylcellulose Sodium