The ability of ethanolic extract of propolis (EEP) to protect mice against gamma irradiation.
Ethanolic extract of propolis (EEP) was tested as a protective agent against gamma irradiation in mice. The mice were exposed to 6 Gy gamma irradiation from a 60Co source, and were treated intraperitoneally with EEP, administered before and after their irradiation. While the non-treated mice expired within 12 weeks, the mice that received a series of EEP treatments survived the irradiation, and their leucocyte count as well as their spleens' plaque-forming activity returned to normal. It is suggested that an antioxidant and a free radical scavenger in the EEP are responsible for the radiation protective effect of the extract of this natural product.
Scheller
S
S
Department of Microbiology, Silesian School of Medicine, Zabrze-Rokitnica, Poland.
Gazda
G
G
Krol
W
W
Czuba
Z
Z
Zajusz
A
A
Gabrys
J
J
Shani
J
J
D000818:Animals; D001516:Bees; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D011429:Propolis / Q000494:pharmacology*; D011837:Radiation-Protective Agents / Q000494:pharmacology*; D012116:Resins, Plant / Q000494:pharmacology*; D014916:Whole-Body Irradiation
D011837:Radiation-Protective Agents; D012116:Resins, Plant; D011429:Propolis