Effects of inhaled acids on lung biochemistry.
Effects of respirable aerosols of sulfuric acid, ammonium sulfate, sodium sulfite, and ammonium persulfate on lungs of rats are reviewed. The literature regarding interactions between ozone or nitrogen dioxide and acidic aerosols (ammonium sulfate, sulfuric acid) is discussed. An unexpected interaction between nitrogen dioxide and sodium chloride aerosol is also discussed. An attempt is made to identify bases for prediction of how and when acid aerosols might potentiate effects of inhaled gases.
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Department of Internal Medicine, University of California, Davis 95616.
D015258:Acid Rain / Q000633:toxicity*; D000336:Aerosols; D000393:Air Pollutants / Q000633:toxicity*; D000645:Ammonium Sulfate / Q000633:toxicity; D000818:Animals; D004305:Dose-Response Relationship, Drug; D005557:Formaldehyde / Q000633:toxicity; D008168:Lung / Q000187:drug effects*; D009585:Nitrogen Dioxide / Q000633:toxicity; D010126:Ozone / Q000633:toxicity; D051381:Rats; D012965:Sodium Chloride / Q000633:toxicity; D013447:Sulfites / Q000633:toxicity; D013464:Sulfuric Acids / Q000633:toxicity
D015258:Acid Rain; D000336:Aerosols; D000393:Air Pollutants; D013447:Sulfites; D013464:Sulfuric Acids; D005557:Formaldehyde; D012965:Sodium Chloride; D010126:Ozone; C033158:sulfuric acid; D009585:Nitrogen Dioxide; D000645:Ammonium Sulfate; C025026:sodium sulfite