title: Intestinal trichomonads (Tritrichomonas mobilensis) in the natural host Saimiri sciureus and Saimiri boliviensis.
abstract: A retrospective study of cecal and colonic tissues from 28 squirrel monkeys (Saimiri sciureus and Saimiri boliviensis) demonstrated enteric trichomonads within luminal crypts. Twenty-one of 28 (75%) had trichomonads in the mucosal epithelium either in cup-like depressions or intraepithelial vacuoles. Organisms were also beneath the superficial luminal mucosal epithelium and between the basement membrane and crypt epithelial cells. Immunoperoxidase staining also identified organisms within the lamina propria and submucosa. Additional histologic changes included mucosal ulceration, multifocal cryptitis, and focal epithelial necrosis. Most areas containing trichomonads did not have an associated inflammatory response.
authors.affiliation: Department of Comparative Medicine, University of South Alabama College of Medicine, Mobile.
authors.forename: J M
authors.initials: JM
authors.lastname: Scimeca
authors.forename: D E
authors.initials: DE
authors.lastname: Culberson
authors.forename: C R
authors.initials: CR
authors.lastname: Abee
authors.forename: W A
authors.initials: WA
authors.lastname: Gardner
mesh_terms: D000818:Animals; D002427:Cebidae / Q000469:parasitology*; D002432:Cecum / Q000469:parasitology / Q000473:pathology; D003106:Colon / Q000469:parasitology / Q000473:pathology; D007411:Intestinal Diseases, Parasitic / Q000469:parasitology / Q000473:pathology / Q000662:veterinary*; D007413:Intestinal Mucosa / Q000469:parasitology; D008992:Monkey Diseases / Q000469:parasitology* / Q000473:pathology; D009336:Necrosis; D011528:Protozoan Infections / Q000469:parasitology / Q000473:pathology; D011529:Protozoan Infections, Animal; D012189:Retrospective Studies; D012453:Saimiri / Q000469:parasitology*; D014318:Tritrichomonas / Q000302:isolation & purification*