An unusual familial muscle disorder.
Autosomal dominant inheritance of an unusual muscle disease is reported in a family. The pathological appearance, of regularly arranged markedly atrophic muscle fibres without other evidence of disturbed innervation, are similar in each case. However, the onset of the disease, its distribution and its progression has varied within the family.
Cumming
W J
WJ
Department of Neurology, Withington Hospital, Manchester, UK.
Kristmundsdottir
F
F
Mahon
M
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D002869:Chromosome Aberrations / Q000235:genetics* / Q000473:pathology; D025063:Chromosome Disorders; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000473:pathology; D009468:Neuromuscular Diseases / Q000235:genetics* / Q000473:pathology; D010375:Pedigree; D014057:Tomography, X-Ray Computed