title: Sinus histiocytosis with massive lymphadenopathy: bilateral orbital involvement spanning 17 years.
abstract: We report a case of sinus histiocytosis with massive lymphadenopathy (SHML) with a right inferior orbital mass. The mass was excised and, on histopathologic examination, was believed to be a "lipogranuloma." Thirteen years later, the patient was seen at our institution for what appeared to be a recurrent orbital mass. Orbital tumors were removed from the right superior and inferior orbit and from the left superior orbit. Histopathologic examination of these tumors at this institution and at the Armed Forces Institute of Pathology showed them to be SHML. The original biopsy tissue obtained in 1969 was reexamined and found also to be SHML. The clinical and histopathologic features of this disease are discussed.
authors.affiliation: Department of Ophthalmology, Wake Forest University Medical Center, Winston-Salem, North Carolina.
authors.forename: J R
authors.initials: JR
authors.lastname: Marion
authors.forename: K R
authors.initials: KR
authors.lastname: Geisinger
mesh_terms: D000328:Adult; D005260:Female; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008206:Lymphatic Diseases / Q000473:pathology*; D008207:Lymphatic Metastasis; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009915:Orbit / Q000473:pathology; D009918:Orbital Neoplasms / Q000473:pathology*; D010255:Paranasal Sinus Neoplasms / Q000473:pathology*; D014057:Tomography, X-Ray Computed