Stimulatory effects of protein synthesis inhibitors on the spreading rate of 3T3 cells.
Three protein synthesis inhibitors, puromycin, cycloheximide and anisomycin were found to increase the rate of spreading of Swiss-3T3 cells after 1 h incubation in the presence of low concentrations of serum. Data from experiments with anisomycin suggest that this effect is roughly proportional to the extent of inhibition of protein synthesis.
Verger
C
C
C.N.R.S., Villejuif, France.
Petrovic
M
M
Imbenotte
J
J
D000818:Animals; D000841:Anisomycin / Q000494:pharmacology*; D003513:Cycloheximide / Q000494:pharmacology*; D051379:Mice; D011500:Protein Synthesis Inhibitors / Q000494:pharmacology*; D011691:Puromycin / Q000494:pharmacology*; D011759:Pyrrolidines / Q000494:pharmacology*; D014407:Tumor Cells, Cultured / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*
D011500:Protein Synthesis Inhibitors; D011759:Pyrrolidines; D011691:Puromycin; D000841:Anisomycin; D003513:Cycloheximide