Effect of aerobic training on left ventricular diastolic filling.
The effects of aerobic training on left ventricular diastolic filling were determined and related to the effects on maximal oxygen uptake, left ventricular systolic function, and left ventricular mass. Nine untrained healthy males with a mean age of 32 years underwent a ten-week program of bicycle training. Echocardiographic left ventricular mass, maximal oxygen uptake, radionuclide-derived left ventricular ejection fraction, and average left ventricular filling rate were obtained before and after training. Training resulted in significant increases in maximal oxygen uptake (from 30 +/- 6 (mean +/- S.D.) to 40 +/- 7 ml/kg/min, p less than 0.001) and average left ventricular filling rate (from 2.04 +/- 0.36 to 2.22 +/- 0.31 end-diastolic volumes/sec, p less than 0.05), but no changes in heart rate, systolic blood pressure, left ventricular ejection fraction, or left ventricular mass. These data indicate that short-term high-intensity aerobic training enhances average left ventricular diastolic filling independent of any change in left ventricular geometry, systolic function, heart rate, or blood pressure.
Senior
D G
DG
Waters
K L
KL
Cassidy
M
M
Crucitti
T
T
Shapiro
H
H
Riba
A L
AL
D000328:Adult; D003971:Diastole; D015444:Exercise; D006439:Hemodynamics; D006801:Humans; D008297:Male; D009200:Myocardial Contraction; D010100:Oxygen / Q000097:blood; D013997:Time Factors; D016276:Ventricular Function
D010100:Oxygen