title: Soft contact lens and corneal changes associated with Visine use.
abstract: Sixteen subjects were fit with Cibasoft clear daily wear contact lenses and were asked to use two drops of tetrahydrozoline (Visine) twice a day for 4 months on one eye. Visual acuity, lens coloration, and slit lamp results were compared to baseline data between the test and control eye of each subject. Visual acuity and lens coloration results showed statistically insignificant changes from baseline. However, clinically important changes in corneal integrity were noted in 26.7% of the subjects.
authors.forename: S M
authors.initials: SM
authors.lastname: Peyton
authors.forename: R G
authors.initials: RG
authors.lastname: Joyce
authors.forename: T B
authors.initials: TB
authors.lastname: Edrington
mesh_terms: D000287:Administration, Topical; D000328:Adult; D003263:Contact Lenses, Hydrophilic / Q000009:adverse effects*; D003315:Cornea / Q000187:drug effects*; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000494:pharmacology*; D008297:Male; D014792:Visual Acuity
chemical_list: D007093:Imidazoles; C005810:tetrahydrozoline