title: Oculogyric crisis after metoclopramide therapy.
abstract: Oculogyric crisis developed in a 21-year-old girl after 5 oral doses of 10 mg of metoclopramide. The symptoms were relieved by i.v. administration of diphenhydramine hydrochloride. Although ocular side effects of metoclopramide are rare, it can induce an alarming oculogyric crisis in some sensitive subjects. The mechanism of oculogyric crises is unclear but the characteristics of the condition and some known causes are discussed. Advice is given on optometric management.
authors.affiliation: Hong Kong Polytechnic.
authors.forename: M
authors.initials: M
authors.lastname: Edwards
authors.forename: M W
authors.initials: MW
authors.lastname: Koo
authors.forename: R K
authors.initials: RK
authors.lastname: Tse
mesh_terms: D000328:Adult; D004155:Diphenhydramine / Q000627:therapeutic use; D005128:Eye Diseases / Q000209:etiology*; D005260:Female; D005403:Fixation, Ocular; D006801:Humans; D008787:Metoclopramide / Q000009:adverse effects*
chemical_list: D004155:Diphenhydramine; D008787:Metoclopramide