title: A specific diagnostic antigen of Echinococcus granulosus with an apparent molecular weight of 8 kDA.
abstract: An echinococcus antigen with an apparent molecular weight of 8 kDa was identified as diagnostically important. An immunoblot assay using this antigen was 91% sensitive for surgically confirmed Echinococcus granulosus hydatid disease of the liver. Specificity was 100% for echinococcosis. Marked cross-reactivity was observed with serum specimens from patients with E. multilocularis and E. vogeli infections. The 8 kDa component was not related to the widely recognized echinococcus antigen 5.
authors.affiliation: Division of Parasitic Diseases, Centers for Disease Control, Atlanta, Georgia.
authors.forename: S E
authors.initials: SE
authors.lastname: Maddison
authors.forename: S B
authors.initials: SB
authors.lastname: Slemenda
authors.forename: P M
authors.initials: PM
authors.lastname: Schantz
authors.forename: J A
authors.initials: JA
authors.lastname: Fried
authors.forename: M
authors.initials: M
authors.lastname: Wilson
authors.forename: V C
authors.initials: VC
authors.lastname: Tsang
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal; D000947:Antigens, Helminth / Q000302:isolation & purification*; D002162:Camelus; D002417:Cattle; D003670:Deer; D004443:Echinococcosis / Q000175:diagnosis* / Q000378:metabolism; D004446:Echinococcus / Q000276:immunology*; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D015151:Immunoblotting; D008970:Molecular Weight; D012698:Serologic Tests / Q000379:methods; D012756:Sheep
chemical_list: D000911:Antibodies, Monoclonal; D000947:Antigens, Helminth