Meningeal nodules with features of extranodal sinus histiocytosis with massive lymphadenopathy.
We present an unusual case of multiple intracranial meningeal nodules in a 30-year-old man. Histologically, the nodules consisted predominantly of plasma cells, histiocytes, and lymphoid cells with Russell bodies and emperipolesis. Emperipolesis may be a clue to understanding the pathogenesis of the process that has features consistent with so-called sinus histiocytosis with massive lymphadenopathy in the extranodal location.
Song
S K
SK
Department of Pathology, Mount Sinai School of Medicine, City University of New York, New York.
Schwartz
I S
IS
Strauchen
J A
JA
Huang
Y P
YP
Sachdev
V
V
Daftary
D R
DR
Vas
C J
CJ
D000328:Adult; D006801:Humans; D008198:Lymph Nodes; D008206:Lymphatic Diseases / Q000473:pathology*; D008297:Male; D008577:Meningeal Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D008579:Meningioma / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed