Cell type-specific distribution of cathepsin B and D immunoreactivity within the rabbit retina.
The cellular localization of cathepsin B and D immunoreactivity was demonstrated at the light microscopic level in the retina of adult rabbits by use of the peroxidase-antiperoxidase technique. Antisera were raised against rat liver enzymes. Whereas cathepsin D immunoreactivity was confined to Müller (glial) cells, cathepsin B was demonstrated in some, but not all, neuronal cell types. It is proposed that the two enzymes might carry different functions within the neuronal versus glial compartment.
Bernstein
H G
HG
Institute of Anatomy, Medical Academy, Magdeburg, G.D.R.
Reichenbach
A
A
Kirschke
H
H
Wiederanders
B
B
D000818:Animals; D002403:Cathepsins / Q000032:analysis*; D007150:Immunohistochemistry; D011817:Rabbits; D012160:Retina / Q000378:metabolism*
D002403:Cathepsins