title: Malignant melanoma associated with human immunodeficiency virus infection in three homosexual men.
abstract: This report concerns three patients with human immunodeficiency virus (HIV) infection in whom malignant melanoma developed. One patient had metastatic malignant melanoma, one had iris melanoma, and one had a single skin melanoma. All three had lower absolute numbers of CD4+ cells than a control group, and the severity of their disease was inversely proportional to the absolute number of CD4+ cells. This report suggests an association between the immunodeficiency resulting from HIV infection and the development of malignant melanoma.
authors.affiliation: Centre for Immunology, St. Vincent's Hospital, Sydney, NSW, Australia.
authors.forename: B
authors.initials: B
authors.lastname: Tindall
authors.forename: R
authors.initials: R
authors.lastname: Finlayson
authors.forename: K
authors.initials: K
authors.lastname: Mutimer
authors.forename: F A
authors.initials: FA
authors.lastname: Billson
authors.forename: V F
authors.initials: VF
authors.lastname: Munro
authors.forename: D A
authors.initials: DA
authors.lastname: Cooper
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000276:immunology; D000328:Adult; D001855:Bone Marrow Diseases / Q000150:complications; D001859:Bone Neoplasms / Q000150:complications; D005153:Facial Neoplasms / Q000150:complications; D006801:Humans; D008297:Male; D008545:Melanoma / Q000150:complications* / Q000276:immunology; D009894:Opportunistic Infections / Q000150:complications; D012878:Skin Neoplasms / Q000150:complications* / Q000276:immunology; D013899:Thoracic Neoplasms / Q000150:complications