title: Early radiolucencies following cemented total hip replacement. Influence of postoperative treatment with indomethacin.
abstract: The influence of treatment with indomethacin in the first 6 postoperative weeks on the incidence of early loosening and radiolucencies following cemented total hip replacement were studied in 102 hips. Ninety-nine hips in 99 patients without postoperative antiinflammatory treatment served as control group. One year after surgery, two patients in the indomethacin group and five patients in the control group were suspected of having loosening of one or both prosthetic components. However, no patients had a revision. The lateral acetabular cement-bone interface most frequently showed a radiolucent line. Concerning the incidence of radiolucent lines in any acetabular or femoral cement-bone interface zone, no difference could be shown between the two groups. When evaluated 1 year after surgery, postoperative treatment with indomethacin does not increase the incidence of aseptic loosening or cement-bone interface radiolucencies in cemented total hip replacement.
authors.affiliation: Department of Orthopedic Surgery, Kolding Hospital, Denmark.
authors.forename: P
authors.initials: P
authors.lastname: Kjaersgaard-Andersen
authors.forename: S A
authors.initials: SA
authors.lastname: Schmidt
authors.forename: N W
authors.initials: NW
authors.lastname: Pedersen
authors.forename: S S
authors.initials: SS
authors.lastname: Kristensen
authors.forename: P
authors.initials: P
authors.lastname: Pedersen
mesh_terms: D001843:Bone Cements / Q000627:therapeutic use; D001861:Bone Regeneration; D004868:Equipment Failure; D006621:Hip Joint / Q000000981:diagnostic imaging*; D006622:Hip Prosthesis; D006801:Humans; D007213:Indomethacin / Q000009:adverse effects* / Q000627:therapeutic use; D011859:Radiography
chemical_list: D001843:Bone Cements; D007213:Indomethacin