Immunocytochemical localization of serotonin in the pineal gland.
The localization of serotonin (5HT) in the rat pineal gland during daylight conditions was investigated by light and electron microscopy using a polyclonal antibody to 5HT and the immunocytochemical method of peroxidase-antiperoxidase (PAP). Thin varicose 5HT fibers were found distributed in the gland at light microscopy level. Ultrastructural observations revealed the presence of terminal endings containing 5HT and localized mainly in the perivascular spaces, labeled with dense diaminobenzidine (DAB) deposits.
Heredia Chons
M
M
López Costa
J J
JJ
Pellegrino de Iraldi
A
A
Pecci Saavedra
J
J
D000818:Animals; D002940:Circadian Rhythm; D007124:Immunoenzyme Techniques; D008297:Male; D008854:Microscopy, Electron; D010870:Pineal Gland / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000032:analysis* / Q000276:immunology
D012701:Serotonin