Cefmetazole versus cefoxitin in prevention of infections after abdominal surgery.
Patients undergoing elective abdominal surgery were randomized to receive cefmetazole or cefoxitin in a three-dose perioperative prophylactic regimen. There were three infections in 89 evaluable patients receiving cefmetazole. There were six infections in 39 patients receiving cefoxitin. Both regimens were acceptable with minimal toxicity.
Plouffe
J F
JF
Department of Internal Medicine, Ohio State University Hospitals, Columbus 43210.
D000005:Abdomen / Q000601:surgery*; D000328:Adult; D015311:Cefmetazole / Q000009:adverse effects / Q000627:therapeutic use*; D002440:Cefoxitin / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011292:Premedication; D011897:Random Allocation; D013530:Surgical Wound Infection / Q000517:prevention & control*
D015311:Cefmetazole; D002440:Cefoxitin