[Acetylhydroxamic acid in the treatment of nephrolithiasis, caused by infection with urease forming microorganisms].
Acetohydroxam acid (500-1000 mg/d) inhibit the activity of the bacterial urease successfully due to reduction of ammonia excretion and urinary pH value in the patients. Acetohydroxam acid should be used in patients after operative treatment of urolithiasis due to infection with carbamidesplitting bacteria.
Lorenz
J
J
Abteilung für Urologie, Institut für Umweltschutz der Technischen Hochschule Wrocław.
Lorenz
K
K
Dabrowska
B
B
Kowal
R
R
D000641:Ammonia / Q000652:urine; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006877:Hydroxamic Acids / Q000627:therapeutic use*; D007669:Kidney Calculi / Q000188:drug therapy*; D008826:Microbial Sensitivity Tests; D011512:Proteus Infections / Q000188:drug therapy*; D011514:Proteus vulgaris / Q000187:drug effects; D014510:Urease / Q000037:antagonists & inhibitors*; D014552:Urinary Tract Infections / Q000188:drug therapy*
D006877:Hydroxamic Acids; C006358:acetohydroxamic acid; D000641:Ammonia; D014510:Urease
Acetylhydroxamsäure bei der Behandlung der Nephrolithiasis, die durch eine Infektion mit ureasebildenden Mikroorganismen bedingt ist.