Gene amplification correlates with sister chromatid exchange in B16 murine and human melanoma and human astrocytoma cell lines.
The incidence of double minute chromosomes and sister chromatid exchanges has been examined in four variant lines of the B16 murine melanoma, two human melanoma and two astrocytoma cell lines. The incidence of double minutes and sister chromatid exchanges appears to be strongly associated in these cell lines.
Lakshmi
M S
MS
Cancer Research Unit, Medical School, University of Newcastle upon Tyne, U.K.
Sherbet
G V
GV
D000818:Animals; D001254:Astrocytoma / Q000235:genetics*; D005784:Gene Amplification; D006801:Humans; D008545:Melanoma / Q000235:genetics*; D051379:Mice; D012854:Sister Chromatid Exchange; D014407:Tumor Cells, Cultured