[Antigen recognition and signal transduction in T lymphocytes].
Stopped-flow fluorometry gave a unique opportunity to observe a direct cellular interaction between functionally different subsets of lymphocytes in vitro. By this method the molecular mechanism of receptor-mediated recognition and signaling in T lymphocytes (T cells) has been well analyzed. The method is further in progress to observe calcium signals in a single T lymphocyte by using a digital imaging fluorescence microscope.
Nakanishi
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D000818:Animals; D000941:Antigens / Q000276:immunology*; D002118:Calcium / Q000378:metabolism / Q000502:physiology; D005470:Fluorometry; D008213:Lymphocyte Activation; D008285:Major Histocompatibility Complex / Q000276:immunology; D015290:Second Messenger Systems; D015398:Signal Transduction; D013601:T-Lymphocytes / Q000276:immunology*
D000941:Antigens; D002118:Calcium