Purification of alpha-ketoaldehyde dehydrogenase from the human liver and its possible significance in the control of glycation.
Alfa-ketoaldehyde dehydrogenase, which was extracted and purified from human livers, may act on carbonyl compounds, such as 3-deoxyglucosone, and be involved in the control of glycation (Maillard reaction) in the body.
Oimomi
M
M
Second Department of Internal Medicine, Kobe University School of Medicine, Japan.
Hata
F
F
Igaki
N
N
Nakamichi
T
T
Baba
S
S
Kato
H
H
D000328:Adult; D000445:Aldehyde Oxidoreductases / Q000302:isolation & purification* / Q000378:metabolism; D006706:Homeostasis; D006801:Humans; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D015416:Maillard Reaction; D008297:Male; D008970:Molecular Weight
D000445:Aldehyde Oxidoreductases; C021928:2-oxoaldehyde dehydrogenase (NAD+)