[The effect of flurbiprofen in acute ankle distortions].
The efficacy of flurbiprofen was studied by means of a double-blind randomized clinical trial involving 50 patients with an acute lateral ankle distortion (grade I). It could not be demonstrated that the NSAID shortened the duration of convalescence after this injury. Neither the pain nor the swelling showed a statistically significant decrease. Side effects were more frequent in patients treated with flurbiprofen. In view of these findings use of flurbiprofen in the treatment of acute ankle distortions is to be regarded as inadvisable.
de Nies
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Lagrand
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Patka
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D000293:Adolescent; D000328:Adult; D016512:Ankle Injuries; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D005480:Flurbiprofen / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy; D011422:Propionates / Q000627:therapeutic use*; D011446:Prospective Studies; D011897:Random Allocation; D013180:Sprains and Strains / Q000188:drug therapy*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D011422:Propionates; D005480:Flurbiprofen
Het effect van flurbiprofen bij acute enkeldistorsies.