title: [Tumor markers in malignant choroid melanoma].
abstract: Antibodies against tumor-associated antigens ("tumor markers") can be used for the diagnosis of malignant tumors. Eight different monoclonal antibodies, that can recognize tumor-associated antigens of dermal melanomas, were tested in cryostat sections of uveal melanomas. The uveal melanomas showed antigenic differences (e.g., gangliosides) and common antigens (e.g. high molecular weight melanoma-associated antigen) in comparison to dermal melanomas. The implications of these results for diagnosing and even treating uveal melanomas are discussed.
authors.forename: O F
authors.initials: OF
authors.lastname: Scheiffarth
authors.forename: J
authors.initials: J
authors.lastname: Strobl
authors.forename: F H
authors.initials: FH
authors.lastname: Stefani
authors.forename: K G
authors.initials: KG
authors.lastname: Riedel
authors.forename: K
authors.initials: K
authors.lastname: Scheidhauer
mesh_terms: D000469:Alkaline Phosphatase / Q000032:analysis*; D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor / Q000032:analysis*; D002829:Choroid / Q000473:pathology; D002830:Choroid Neoplasms / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D008545:Melanoma / Q000473:pathology*; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins / Q000032:analysis*
chemical_list: D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins; D000469:Alkaline Phosphatase
vernacular_title: Tumormarker beim malignen Aderhautmelanom.