[Morphobiophysical features of the duodenal mucosa in patients with duodenal ulcers].
Chronic duodenitis in patients with duodenal ulcer is characterized by substantial morphofunctional changes in the mucosa, decreased transmural potential difference and definite patterns of carbohydrate-containing biopolymer production, the initial changes being manifested as neutral glycoprotein hypersecretion with their subsequent diminished synthesis rates, followed by a more pronounced drop of sialo- and sulfoglycoprotein levels. A correlation was found between the severity of duodenitis, morphometric and histochemical parameters, and gastric pepsin secretion rates (hypersecretion). It is suggested that these changes are etiopathogenetically common.
Mogil'naia
G M
GM
Fisher
A A
AA
Gorban'
V V
VV
D000293:Adolescent; D000328:Adult; D000368:Aged; D001704:Biopolymers; D002908:Chronic Disease; D004381:Duodenal Ulcer / Q000473:pathology*; D004382:Duodenitis / Q000473:pathology; D004386:Duodenum / Q000473:pathology*; D005260:Female; D006023:Glycoproteins / Q000032:analysis; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012795:Sialoglycoproteins / Q000032:analysis
D001704:Biopolymers; D006023:Glycoproteins; D012795:Sialoglycoproteins
Morfobiofizicheskie osobennosti slizistoĭ obolochki dvenadtsatiperstnoĭ kishki u bol'nykh duodenal'noĭ iazvoĭ.