Vascular changes following hypothermic preservation.
This study identifies ultrastructural changes in the endothelium due to hypothermic HP-5 perfusion. These changes appear to be reversible and a manifestation of hypothermic hypoxia. This data provides a basis for improving perfusion techniques in both hypothermic preservation and cryoprotectant introduction and removal for cryopreservation.
Neil
D A
DA
University of Queensland, Department of Surgery, Brisbane, Australia.
Pollock
G A
GA
Molyneux
G S
GS
Hardie
I R
IR
D000818:Animals; D003080:Cold Temperature; D004730:Endothelium, Vascular / Q000473:pathology / Q000648:ultrastructure*; D008297:Male; D008638:Mesenteric Arteries / Q000473:pathology / Q000648:ultrastructure*; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values; D014021:Tissue Preservation