Fragile sites and statistics.
A simple and reliable statistical method is proposed to distinguish real fragile sites from the casual accumulation of aberrations that can occur as a consequence of random distribution. It is based on a study of the expected random distribution, assumed to be equal to a Poisson distribution, with the expected value of events per band as the mean.
Mariani
T
T
Istituto di Mutagenesi e Differenziamento C.N.R., Pisa, Italy.
D043283:Chromosome Fragile Sites; D002873:Chromosome Fragility; D006801:Humans; D011336:Probability; D012984:Software; D013223:Statistics as Topic