title: Computed tomography in intracranial, supratentorial metastases in children.
abstract: This study compares the CT characteristics in a consecutive sample of supratentorial metastases (n = 31) with primary tumors of the same location (n = 49) in childhood. Postcontrast CT was performed in all but one of the metastases cases. In all but one of these children the location and type of primary tumor was known at time of occurrence of cerebral metastasis. Primary CNS tumors (n = 12) had a higher incidense of supratentorial metastatic spread than tumor originating elsewhere. Three children had diffuse subarachnoid seeding, while 28 had solid tumors (21 solitary, 7 multiple). The predilection location for the solid metastases was the gray-white matter junction (n = 12). The following CT findings were significantly less frequent in metastases than in primary tumors (P less than 0.05): Midline location, calcification and cyst formation. On the other hand bleeding, pronounced contrast enhancement and location in the gray-white matter junction were more frequent in the metastatic group (P less than 0.05).
authors.affiliation: Department of Radiology, Rigshospitalet, University of Copenhagen, Denmark.
authors.forename: H
authors.initials: H
authors.lastname: Pedersen
authors.forename: J
authors.initials: J
authors.lastname: McConnell
authors.forename: D C
authors.initials: DC
authors.lastname: Harwood-Nash
authors.forename: C R
authors.initials: CR
authors.lastname: Fitz
authors.forename: S H
authors.initials: SH
authors.lastname: Chuang
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D002528:Cerebellar Neoplasms / Q000000981:diagnostic imaging; D002648:Child; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000000981:diagnostic imaging / Q000556:secondary; D008297:Male; D008527:Medulloblastoma / Q000000981:diagnostic imaging / Q000556:secondary; D012509:Sarcoma / Q000000981:diagnostic imaging / Q000556:secondary; D014057:Tomography, X-Ray Computed