A 45,X/69,XXY fetus.
Post-mortem examination of a 20-week fetus showed incompletely masculinised external genitalia, hypoplastic adrenal glands and minor physical stigmata suggestive of a chromosome abnormality. Gonad and skin were karyotyped and both were found to contain two cell lines, 45,X and 69,XXY. It appears this fetus is a true 45,X/69,XXY mosaic.
Betts
D R
DR
Division of Medical and Molecular Genetics, United Medical School of Guy's Hospital, London, UK.
Fear
C N
CN
Barby
T
T
Seller
M J
MJ
D000028:Abortion, Induced; D004171:Diploidy; D005333:Fetus / Q000473:pathology; D005837:Genitalia, Male / Q000002:abnormalities*; D006801:Humans; D008297:Male; D009030:Mosaicism; D011123:Polyploidy; D012729:Sex Chromosome Aberrations / Q000235:genetics; D014960:X Chromosome