Lamicel does not promote induction of labour. A randomized controlled study.
Lamicel is a synthetic tent, which, when inserted in the cervical canal, dilates the cervix by osmosis. Lamicel as an adjunct to induction of labour with intravenous oxytocin or vaginal prostaglandin E2 has been examined in a randomized controlled trial. Ninety-one pregnant women with an unripe cervix participated in the study. No improvement in efficacy was observed in the Lamicel groups compared to the control groups, neither when induction of labour was performed with oxytocin nor with vaginal prostaglandin.
Lyndrup
J
J
Department of Obstetrics and Gynaecology, Copenhagen University Hospital, Herlev, Denmark.
Legarth
J
J
Dahl
C
C
Philipsen
T
T
Eriksen
P S
PS
D001034:Apgar Score; D002584:Cervix Uteri / Q000502:physiology; D015232:Dinoprostone / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007751:Labor, Induced / Q000379:methods*; D008278:Magnesium Sulfate / Q000008:administration & dosage*; D010121:Oxytocin / Q000008:administration & dosage; D011142:Polyvinyl Alcohol / Q000008:administration & dosage*; D011247:Pregnancy; D011897:Random Allocation
C034860:Lamicel; D010121:Oxytocin; D008278:Magnesium Sulfate; D011142:Polyvinyl Alcohol; D015232:Dinoprostone