Pharmacokinetics of amikacin in African gray parrots.
Amikacin sulfate was administered to African gray parrots at 3 dosages (5, 10, and 20 mg/kg) via 2 routes (IV and IM). The elimination half-time was approximately 1 hour (range, 0.9 to 1.34 hour). The apparent bioavailability of IM administered drug was 61 to 106% and was not dose-related.
Gronwall
R
R
Department of Medical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610.
Brown
M P
MP
Clubb
S
S
D000583:Amikacin / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D000818:Animals; D001682:Biological Availability; D006207:Half-Life; D008657:Metabolic Clearance Rate / Q000662:veterinary; D010311:Parrots / Q000378:metabolism*; D011563:Psittaciformes / Q000378:metabolism*
D000583:Amikacin