[Functional status of the hepatobiliary system during anti-orthostatic hypodynamia].
In 16 male subjects, the hepatic absorption-excretion function and the gallbladder and biliary ducts were investigated using computer scintigraphy and 99mTs-HIDA. Comparison of the data obtained after 6-hour (-20 degrees) and 3-day (10 degrees) antiorthostatic hypodynamics with the baseline data obtained in the supine position demonstrated deterioration of the absorption-excretion function of the liver. In response to a short-term exposure (6 hour) the changes were seen only in subjects with latent or clinically nonmanifest pathologies of the digestive organs. As the exposure continued, changes in the hepatobiliary function became more manifest and significant. It is recommended to study in greater detail changes in the above function and their involvement in the symptom complex of an acute stage of adaptation to microgravity.
Andriako
L Ia
LIa
Bubeev
Iu A
IuA
Gorin
V V
VV
Degtiarev
V A
VA
Kaplan
M A
MA
D000328:Adult; D001659:Biliary Tract / Q000502:physiology*; D006801:Humans; D007103:Immobilization; D008099:Liver / Q000502:physiology*; D008297:Male; D008954:Models, Biological; D010528:Peristalsis; D011187:Posture; D013997:Time Factors; D014893:Weightlessness
Funktsional'noe sostoianie gepatobiliarnoĭ sistemy pri antiortostaticheskoĭ gipodinamii.