Octatropine-methyl-bromide and sulglycotide salt in the short-term treatment of active duodenal ulcer. A double blind endoscopic study of 40 outpatients.
Forty outpatients with endoscopically confirmed duodenal ulcers were entered in a double blind trial. They were randomly allocated to octatropine-methyl-bromide and sulglycotide salt (GVP) or placebo. The results show that the combination of the two drugs is less efficacious than the two constituent substances taken separately, is not more efficacious than placebo in ulcer healing, and is ineffective with regard to ulcer pain.
Dobrilla
G
G
Division of Gastroenterology, Regional General Hospital, Bolzano, Italy.
Valentini
M
M
Bonoldi
M C
MC
Piazzi
L
L
D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D004311:Double-Blind Method; D004338:Drug Combinations / Q000627:therapeutic use; D004381:Duodenal Ulcer / Q000188:drug therapy*; D006801:Humans; D010276:Parasympatholytics / Q000627:therapeutic use*; D016032:Randomized Controlled Trials as Topic; D012795:Sialoglycoproteins / Q000627:therapeutic use*; D013997:Time Factors; D014326:Tropanes / Q000627:therapeutic use*
D000897:Anti-Ulcer Agents; D004338:Drug Combinations; D010276:Parasympatholytics; D012795:Sialoglycoproteins; D014326:Tropanes; C062849:GVP anti-ulcer agent; C009354:sulglicotide; C100237:octotropine methylbromide