title: In vitro activities of temafloxacin (A-62254) and four other antibiotics against Chlamydia trachomatis.
abstract: The in vitro activity of temafloxacin (A-62254), a new quinolone antibiotic, against 13 strains of Chlamydia trachomatis was determined and compared with those of doxycycline, norfloxacin, ciprofloxacin, and difloxacin. Temafloxacin and difloxacin were the most active quinolones tested, with bactericidal activity comparable to that of doxycycline.
authors.affiliation: Department of Medicine, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612.
authors.forename: J
authors.initials: J
authors.lastname: Segreti
authors.forename: H A
authors.initials: HA
authors.lastname: Kessler
authors.forename: K S
authors.initials: KS
authors.lastname: Kapell
authors.forename: G M
authors.initials: GM
authors.lastname: Trenholme
mesh_terms: D042462:4-Quinolones; D000890:Anti-Infective Agents / Q000494:pharmacology*; D002692:Chlamydia trachomatis / Q000187:drug effects*; D004318:Doxycycline / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D024841:Fluoroquinolones; D015363:Quinolones
chemical_list: D042462:4-Quinolones; D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D015363:Quinolones; C054745:temafloxacin; D004318:Doxycycline