title: [Genetic control of the number of copies of type K2 killer plasmids in Saccharomyces cerevisiae].
abstract: 13 non-linked chromosomal mutations derepress the negative genetic control of copy number of K2 yeast killer plasmids and lead to 1.5-2-fold elevating of copy number of that type plasmids -L2A and M2 virus-like dsRNA. The content of both plasmids is increased 3-5-fold in cells with chromosomal ski5 mutation, as compared to the strains of wild type. Expression of ski5 allele is recessive. The dose effect of this allele is observed on haploid and diploid levels. Dominant ochre nonsense suppressors suppress the action of ski5 and the ski6 allele epistates that of ski5.
authors.forename: G F
authors.initials: GF
authors.lastname: Nesterova
authors.forename: M V
authors.initials: MV
authors.lastname: Shabalina
authors.forename: T V
authors.initials: TV
authors.lastname: Bobysheva
authors.forename: E V
authors.initials: EV
authors.lastname: Tuchinskaia
authors.forename: A V
authors.initials: AV
authors.lastname: Stolbova
authors.forename: S G
authors.initials: SG
authors.lastname: Boĭkova
authors.forename: L L
authors.initials: LL
authors.lastname: Skliarova
mesh_terms: D000483:Alleles; D002999:Clone Cells; D004171:Diploidy; D004591:Electrophoresis, Polyacrylamide Gel; D005656:Fungal Proteins / Q000235:genetics*; D015966:Gene Expression Regulation, Fungal; D006238:Haploidy; D055646:Killer Factors, Yeast; D009154:Mutation; D009183:Mycotoxins / Q000235:genetics*; D010957:Plasmids; D012330:RNA, Double-Stranded / Q000235:genetics; D012331:RNA, Fungal / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D029701:Saccharomyces cerevisiae Proteins
chemical_list: D005656:Fungal Proteins; D055646:Killer Factors, Yeast; D009183:Mycotoxins; D012330:RNA, Double-Stranded; D012331:RNA, Fungal; D029701:Saccharomyces cerevisiae Proteins
vernacular_title: Geneticheskiĭ kontrol' kopiĭnosti killernykh plazmid tipa K2 u Saccharomyces cerevisiae.