[Dynamic changes in the indices of lipid metabolism in erythrocyte membranes at different times of the development of alloxan diabetes].
The changes in the content of phospholipids (PL), cholesterol (cr) and its fractions were studied in the processes of lipid peroxidation. At the different periods of alloxan diabetes development the CS/LP ratio coefficient was determined (7, 14, 21 days). The results of our investigations we explain by erythrocyte membranes destruction in the molecular mechanism of which the significant role has played the activation of free radical lipid oxidation processes.
Gevorkian
D M
DM
D000818:Animals; D002784:Cholesterol / Q000097:blood; D002788:Cholesterol Esters / Q000097:blood; D003921:Diabetes Mellitus, Experimental / Q000097:blood* / Q000209:etiology; D004910:Erythrocyte Membrane / Q000378:metabolism*; D005609:Free Radicals; D015227:Lipid Peroxidation; D008055:Lipids / Q000097:blood*; D008297:Male; D010743:Phospholipids / Q000097:blood; D051381:Rats; D013997:Time Factors; D014810:Vitamin E / Q000097:blood
D002788:Cholesterol Esters; D005609:Free Radicals; D008055:Lipids; D010743:Phospholipids; D014810:Vitamin E; D002784:Cholesterol
Dinamika izmeneniĭ nekotorykh pokazateleĭ obmena lipidov v membranakh éritrotsitov v razlichnye sroki razvitiia alloksanovogo diabeta.