title: Splenectomy for massive splenomegaly.
abstract: Twenty-four patients who underwent resection of giant spleen (spleen weight greater than 1.5 kg) have been reviewed to determine the difficulties and benefits of the procedure and, in particular, whether the use of adrenaline injection into the splenic artery could safely reduce technical difficulty. Although morbidity was higher in patients with giant spleens compared with those undergoing resection of smaller spleens the incidence of serious complications was small, and there were no operative or in-hospital deaths. In addition, virtually all patients benefited either on the basis of minimized haematological defect, or palliation of symptoms. Further, the injection of 1 ml of 1:10,000 adrenaline into the splenic artery before splenic mobilization reduced the splenic volume by approximately 40 per cent on average, and resulted in improved exposure, thereby facilitating the procedure.
authors.affiliation: University Department of Surgery, Auckland Hospital, New Zealand.
authors.forename: J H
authors.initials: JH
authors.lastname: Shaw
authors.forename: M
authors.initials: M
authors.lastname: Clark
mesh_terms: D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D004837:Epinephrine / Q000627:therapeutic use; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007430:Intraoperative Care / Q000379:methods; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D013154:Spleen / Q000473:pathology; D013156:Splenectomy / Q000379:methods; D013163:Splenomegaly / Q000209:etiology / Q000601:surgery*
chemical_list: D004837:Epinephrine