Synthesis of derivatives of phosphonic glutathione analogs.
Five analogs of S-t-butyl glutathione containing phosphonic analogs of glycine and glutamic acid were obtained by standard procedures of MA activation in solution. Simultaneous deprotection of phosphonic, carboxylic and amino groups was achieved in the silylation reaction.
Witkowska
H E
HE
Department of Organic Chemistry, Technical University of Gdańsk, Poland.
Wasielewski
C
C
D055598:Chemical Phenomena; D002621:Chemistry; D005978:Glutathione / Q000031:analogs & derivatives / Q000138:chemical synthesis*; D010748:Phosphopeptides / Q000138:chemical synthesis*
D010748:Phosphopeptides; D005978:Glutathione