title: [The induction of stomach cancer in monkeys with N-methyl-N'-nitro-N-nitrosoguanidine].
abstract: Gastric tumors were detected in 2 out of 9 apes following MNNG treatment with a total dose of 800-848 mg/kg (40 mg/kg, thrice a month, 49-50 weeks, via gastric probe). The characteristics, course, symptoms and histologic patterns of the tumors proved comparable with similar neoplasms in humans.
authors.forename: L K
authors.initials: LK
authors.lastname: Sharashidze
authors.forename: D Sh
authors.initials: DSh
authors.lastname: Beniashvili
authors.forename: N I
authors.initials: NI
authors.lastname: Sherenesheva
authors.forename: N G
authors.initials: NG
authors.lastname: Turkiia
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D005260:Female; D008252:Macaca fascicularis; D008297:Male; D008992:Monkey Diseases / Q000139:chemically induced* / Q000473:pathology; D009604:Nitrosoguanidines / Q000633:toxicity*; D013270:Stomach / Q000187:drug effects / Q000473:pathology; D013274:Stomach Neoplasms / Q000139:chemically induced* / Q000473:pathology; D013997:Time Factors
chemical_list: D009604:Nitrosoguanidines
vernacular_title: Induktsiia raka zheludka u obez'ian N-metil-N'-nitro-N-nitrozoguanidinom.