Serum urate level and cancer.
Histograms of the serum uric acid level of cancer patients (n = 501) and healthy controls (n = 15150) are compared. The statistical evaluation of the data yields significantly lower uric acid levels for cancer patients than for healthy persons (P less than 0.0001 for males, P less than 0.001 for females). These results support the theory that reactive species of oxygen (singlet oxygen and oxygen radicals) play an important role during carcinogenesis.
Lickl
E
E
Ludwig Boltzmann Institut fuer klinische Onkologie, Vienna, Austria.
Alth
G
G
Ebermann
R
R
Beck
R H
RH
Tuma
K
K
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000097:blood* / Q000175:diagnosis; D014527:Uric Acid / Q000097:blood*
D014527:Uric Acid