The role of endothelium in vascular reactivity.
1. This review describes the role of vascular endothelium in the response induced by different vasoactive agents. 2. The interaction between endothelium, vascular smooth muscle and platelets is discussed. 3. The hormone control as well as physicochemical alterations that interfere with some endothelium-dependent vascular responses are described.
Carvalho
M H
MH
Departamento de Farmacologia, Universidade de São Paulo, Brasil.
Scivoletto
R
R
Fortes
Z B
ZB
Nigro
D
D
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D004730:Endothelium, Vascular / Q000502:physiology*; D006801:Humans; D009131:Muscle, Smooth, Vascular / Q000187:drug effects; D009569:Nitric Oxide / Q000096:biosynthesis; D009638:Norepinephrine / Q000494:pharmacology; D010974:Platelet Aggregation / Q000502:physiology*; D011817:Rabbits; D051381:Rats; D014655:Vascular Resistance / Q000502:physiology*; D014661:Vasoconstriction / Q000502:physiology*; D014664:Vasodilation / Q000502:physiology*
D009569:Nitric Oxide; D000109:Acetylcholine; D009638:Norepinephrine