title: Hemoperfusion effect on oxygen-carrying function of preserved donor blood and erythrocytic mass.
abstract: The purpose of the study was to explore the preserved (7-21 days) donor blood and erythrocytic mass, following perfusion through hemosorbent SKN-D. After the sorption the oxygen-transport function of erythrocytes was found to improve considerably (oxyhemoglobin dissociation curve was shifted to the right on average by 4-4.2 mm Hg). The energy supply became better (ATP level was increased by 38-59%). In view of the above, long-preserved blood and erythrocytic mass following their perfusion through SKN-D hemosorbent can be considered a sufficiently valid transfusion medium.
authors.affiliation: Kavetsky Institute for Oncology Problems Ukr. SSR AS, All-Union Scientific Surgical Center USSR AMS.
authors.lastname: Khodas MYa
authors.forename: A L
authors.initials: AL
authors.lastname: Belkin
authors.forename: L A
authors.initials: LA
authors.lastname: Mosolova
authors.forename: M S
authors.initials: MS
authors.lastname: Povzhitkova
authors.forename: S F
authors.initials: SF
authors.lastname: Leonova
authors.forename: K A
authors.initials: KA
authors.lastname: Penkrak
authors.forename: M N
authors.initials: MN
authors.lastname: Grischenko
authors.forename: G K
authors.initials: GK
authors.lastname: Pyatnitskaya
mesh_terms: D001692:Biological Transport; D001790:Blood Physiological Phenomena; D001793:Blood Preservation; D004912:Erythrocytes / Q000166:cytology / Q000378:metabolism*; D006464:Hemoperfusion; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010100:Oxygen / Q000378:metabolism*
chemical_list: D010100:Oxygen