title: [Severe forms of effort-induced asthma].
abstract: Severe reactions in exercise-induced asthma (EIA) seem to be underestimated in the published literature. We report two cases of near-miss death from EIA that occurred after a short run. We review 364 exercise tests that were performed between September 1987 and October 1988 by a standardised protocol on a treadmill, on patients with possible EIA. A positive test, defined by a fall of FEV1 of at least 20% was found in 173 patients. From 21 patients with a fall of greater than 50%, 4 presented severe signs of: Cyanosis. Intense dyspnea with impediment of speech. General malaise with hypertension. These 4 patients were not greatly different from patients of the 50% fall group when compared for FEV1 before the test and for heart-rate during the test. They differed in the duration of the asthma attack, which was more protracted, despite the use of beta-2 agonists. The onset of severe reactions is 2.3% of positive tests and seems to be unpredictable.
authors.affiliation: Hôpitaux des Armées, Clarmart.
authors.forename: C
authors.initials: C
authors.lastname: Marotel
authors.forename: F
authors.initials: F
authors.lastname: Natali
authors.forename: J D
authors.initials: JD
authors.lastname: Heyraud
authors.forename: F
authors.initials: F
authors.lastname: Vaylet
authors.forename: P
authors.initials: P
authors.lastname: L'Her
authors.forename: D
authors.initials: D
authors.lastname: Bonnet
authors.forename: P
authors.initials: P
authors.lastname: Allard
mesh_terms: D000328:Adult; D001249:Asthma / Q000209:etiology*; D001250:Asthma, Exercise-Induced / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D005080:Exercise Test; D005260:Female; D005541:Forced Expiratory Volume; D006323:Heart Arrest / Q000209:etiology; D006801:Humans; D008297:Male; D012420:Running
vernacular_title: Formes sévères de l'asthme d'effort.