[Effect of sodium oxybutyrate on the development of a staphylococcal intoxication].
Sodium oxybutyrate (200 and 400 mg/kg) was found to increase life expectancy of the animals poisoned with staphylococcus toxin. The improvement of the blood supply to the bulbar structure of the brain as well as normalization of hemorheological parameters probably underlie the protective effect of the drug.
Brill'
G E
GE
D000818:Animals; D000931:Antidotes; D001427:Bacterial Toxins / Q000506:poisoning*; D001809:Blood Viscosity / Q000187:drug effects; D002415:Cats; D002560:Cerebrovascular Circulation / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D006885:Hydroxybutyrates / Q000627:therapeutic use*; D051379:Mice; D012978:Sodium Oxybate / Q000627:therapeutic use*; D013210:Staphylococcus; D013916:Thrombelastography; D013997:Time Factors; D005680:gamma-Aminobutyric Acid / Q000627:therapeutic use
D000931:Antidotes; D001427:Bacterial Toxins; D006885:Hydroxybutyrates; D005680:gamma-Aminobutyric Acid; D012978:Sodium Oxybate
Vliianie natriia oksibutirata na razvitie stafilokokkovoĭ intoksikatsii.