New hepatoprotective triterpenes from Canarium album.
Canarium album has yielded seven triterpenes of which two appear to be novel. The new triterpenes, which were identified on the basis of spectral characteristics, are urs-12-ene-3 alpha, 16 beta-diol and olean-12-ene-3 alpha, 16 beta-diol. Both compounds exhibited hepatoprotective activity in primary cultured rat hepatocytes intoxicated with D-galactosamine.
Tamai
M
M
Watanabe
N
N
Someya
M
M
Kondoh
H
H
Omura
S
S
Zhang
P L
PL
Chang
R
R
Chen
W M
WM
D000818:Animals; D002478:Cells, Cultured; D004365:Drugs, Chinese Herbal / Q000032:analysis*; D008107:Liver Diseases / Q000188:drug therapy*; D008297:Male; D015394:Molecular Structure; D051381:Rats; D011919:Rats, Inbred Strains; D014315:Triterpenes / Q000302:isolation & purification / Q000494:pharmacology*
D004365:Drugs, Chinese Herbal; D014315:Triterpenes