Azathioprine induced hepatic veno-occlusive disease in rheumatoid arthritis.
A patient with rheumatoid arthritis developed hepatic veno-occlusive disease following the use of azathioprine. Although azathioprine induced veno-occlusive disease is suspected to occur more frequently in patients with autoimmune dysfunction, it has not previously been reported as a complication of treatment in rheumatoid arthritis. The mechanism responsible for this condition remains unknown.
Lemley
D E
DE
Department of Medicine, Veterans Administration Medical Center, Washington, DC 20422.
DeLacy
L M
LM
Seeff
L B
LB
Ishak
K G
KG
Nashel
D J
DJ
D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D001379:Azathioprine / Q000009:adverse effects*; D006504:Hepatic Veno-Occlusive Disease / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D008099:Liver / Q000473:pathology; D008297:Male; D008875:Middle Aged
D001379:Azathioprine