title: Evaluation of jojoba oil as a low-energy fat. 2. Intestinal transit time, stomach emptying and digestibility in short-term feeding studies in rats.
abstract: The influence of jojoba oil (JO) incorporation in the diet on stomach emptying and intestinal transit time, and the digestion and absorption of JO were investigated in short-term feeding studies in rats. The animals were fed purified diets containing 18% (w/w) fat, of which half consisted of a mixture of lard and sunflower seed oil (SF) supplemented with an equivalent amount of JO. The control animals were fed a mixture of lard and SF (18%). No treatment-related differences were observed in the rate of stomach emptying or the intestinal transit time. Comparative lipid analysis of lymph, intestinal content, intestinal mucosa and faeces indicated that most of the ingested JO was degraded and absorbed. Part of the JO was present as wax ester in the lymph. Hydrolysis of JO was much slower than that of triacylglycerols and continued in the alimentary tract beyond the small intestine due to bacterial processes. JO did not influence the absorption of the conventional fat.
authors.affiliation: Unilever Research Laboratorium Vlaardingen, The Netherlands.
authors.forename: P M
authors.initials: PM
authors.lastname: Verschuren
authors.forename: D H
authors.initials: DH
authors.lastname: Nugteren
mesh_terms: D000821:Animal Feed / Q000032:analysis; D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D004041:Dietary Fats / Q000008:administration & dosage* / Q000032:analysis; D004734:Energy Metabolism; D005227:Fatty Acids / Q000032:analysis; D005233:Fatty Alcohols / Q000032:analysis; D005746:Gastric Emptying / Q000187:drug effects*; D007413:Intestinal Mucosa / Q000378:metabolism*; D007422:Intestines / Q000032:analysis / Q000187:drug effects; D008055:Lipids / Q000032:analysis; D008297:Male; D009753:Nutritive Value; D009754:Nuts; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors; D014885:Waxes / Q000008:administration & dosage* / Q000032:analysis / Q000493:pharmacokinetics
chemical_list: D004041:Dietary Fats; D005227:Fatty Acids; D005233:Fatty Alcohols; D008055:Lipids; D014885:Waxes; C034743:jojoba wax