title: T staging of the laryngohypopharyngeal carcinoma. A 7-year multidisciplinary experience.
abstract: Sixty-six whole-organ sectioned, nonirradiated, laryngopharyngectomy specimens that were removed because of cancer during a 7-year period were uniformly examined to determine the accuracy of perioperative T staging by high-resolution computed tomography (CT) and clinical evaluation (indirect-direct laryngoscopy) by comparing this preoperative staging with the postsurgical pathologic staging. The accuracy of the clinical vs CT staging for laryngeal carcinomas was 58.8% vs 70.6%, whereas the accuracy of the staging by combination of the two modalities was 88.2%. Combined staging modalities showed the same accuracy for laryngeal and hypopharyngeal carcinomas (88.2%), whereas clinical staging accuracy for hypopharyngeal carcinomas was lower (52.9%) and CT accuracy was higher (82.4%) than that observed for laryngeal carcinomas. In the majority of the cases that were staged inaccurately, the error was one of under-estimation: in particular, tumors confined to the mucosa and early infiltration of laryngeal fat spaces were not detected by CT.
authors.affiliation: Division of Pathology, Centro di Riferimento Oncologico, Aviano, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Sulfaro
authors.forename: L
authors.initials: L
authors.lastname: Barzan
authors.forename: F
authors.initials: F
authors.lastname: Querin
authors.forename: M
authors.initials: M
authors.lastname: Lutman
authors.forename: G
authors.initials: G
authors.lastname: Caruso
authors.forename: R
authors.initials: R
authors.lastname: Comoretto
authors.forename: R
authors.initials: R
authors.lastname: Volpe
authors.forename: A
authors.initials: A
authors.lastname: Carbone
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D007013:Hypopharynx / Q000473:pathology; D007822:Laryngeal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D007830:Larynx / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010610:Pharyngeal Neoplasms / Q000473:pathology*; D011300:Preoperative Care; D014057:Tomography, X-Ray Computed