[A long-term follow-up study of the histologically confirmed chronic liver diseases in the Juntedo University Hospital].
In order to calculate the survival rate and elucidate the risk factors of liver cancer, 1,034 patients of the chronic liver diseases were followed up for 7.1 years of average. All patients were confirmed histologically from 1973 to 1982 in Juntendo University Hospital as liver cirrhosis (367), liver fibrosis (27), and chronic hepatitis (640). Until the end of 1986, 244 cases were died including 52 cases of liver cancer. The 10 years survival rate by Kaplan-Meier's method ranged from 39.85 for male liver cirrhosis to 80.64 for male chronic hepatitis. The results of proportional hazard model for male liver cirrhosis revealed that drinking alcohol affected negatively to the death from liver cancer, and that cigarette smoking and no history of operation due to portal hypertension affected slightly to it and that HBs antigen, history of blood transfusion and history of acute hepatitis almost have no relation to it.
Inaba
Y
Y
Dept. of Hygiene, Juntendo Univ. School of Med.
Namihisa
T
T
Ichikawa
S
S
Kikuchi
S
S
D000428:Alcohol Drinking; D002908:Chronic Disease; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006505:Hepatitis / Q000401:mortality; D006801:Humans; D007564:Japan; D008103:Liver Cirrhosis / Q000401:mortality; D008107:Liver Diseases / Q000401:mortality* / Q000473:pathology; D008113:Liver Neoplasms / Q000401:mortality; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects