[Glutathione and ascorbic acid metabolism and antioxidant enzyme activity in the tissues of vitamin E-deficient rats].
In has been shown in the experiments on male rats that alimentary vitamin E deficit causes the decrease of reduced glutathione and ascorbic acid concentration in the liver and lungs and that of glutathione-S-transferase, glutathione reductase in the liver and lungs, catalase in the liver and glutathione peroxidase in the heart activity, but increases the amount of glutathione disulfide in the liver and lungs and superoxide dismutase and gamma-glutamyltransferase activity in the liver. The data obtained show the selective character of reaction participants of the antioxidant system of rats' organism to the deficit of one of the antioxidant factors--vitamin E and also testify to complex interrelation between separate members of this system.
Pentiuk
A A
AA
Lankin
V Z
VZ
Iakovleva
O A
OA
Konovalova
G G
GG
Borisenko
B A
BA
D000818:Animals; D000975:Antioxidants; D001205:Ascorbic Acid / Q000378:metabolism*; D002374:Catalase / Q000378:metabolism; D003545:Cysteine / Q000378:metabolism; D005978:Glutathione / Q000031:analogs & derivatives / Q000378:metabolism*; D019803:Glutathione Disulfide; D008099:Liver / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013482:Superoxide Dismutase / Q000378:metabolism; D014811:Vitamin E Deficiency / Q000378:metabolism*
D000975:Antioxidants; D002374:Catalase; D013482:Superoxide Dismutase; D005978:Glutathione; D003545:Cysteine; D001205:Ascorbic Acid; D019803:Glutathione Disulfide
Obmen glutationa, askorbinovoĭ kisloty i aktivnost' antioksidantnykh fermentov v tkaniakh krys, defitsitnykh po vitaminu E.