Lymphomas: the impact of chemotherapy on survival.
Hodgkin's disease and non-Hodgkin's lymphoma are among the most sensitive tumours to chemotherapy. Response, even if complete, does not invariably result in cure. Chemotherapy has had a major impact on survival for patients with advanced Hodgkin's disease and in patients with both early and advanced high grade lymphoma. However, even in these two categories only 30-50% of patients can expect to be cured. Chemotherapy has had a major influence on the palliation of disease in patients with low grade lymphoma; however, it has not much influenced the long natural history of this group of diseases and no patients are cured by this or any other modality.
Gore
M E
ME
Institute of Cancer Research, Royal Marsden Hospital, Sutton, Surrey.
McElwain
T J
TJ
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D016026:Bone Marrow Transplantation; D003131:Combined Modality Therapy; D006801:Humans; D008223:Lymphoma / Q000188:drug therapy* / Q000401:mortality; D012008:Recurrence; D015996:Survival Rate
D000970:Antineoplastic Agents