[Experience in the photochemotherapy of psoriasis with rectal administration of the photosensitizer].
The authors compare the efficacy and tolerance of rectal (in suppositories) and oral administration of puvalen in 117 patients. The therapy has been highly effective in both the groups; clinical remission has been achieved in 78% of Group 1 patients and in 80% of Group 2 ones. Rectal puvalen has been better tolerated; the incidence rate of side effects has been 4 times lower. This recommends the rectal route of puvalen administration for wide practice, particularly in patients with subclinical abnormalities of the liver and gastrointestinal system.
Shinskiĭ
G E
GE
Bazhina
N R
NR
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D004341:Drug Evaluation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008730:Methoxsalen / Q000008:administration & dosage* / Q000009:adverse effects; D008875:Middle Aged; D011701:PUVA Therapy / Q000379:methods*; D011565:Psoriasis / Q000188:drug therapy*; D013488:Suppositories
D013488:Suppositories; D008730:Methoxsalen
Opyt fotokhimioterapii psoriaza s rektal'nym vvedeniem fotosensibilizatora.