[The effect of mercasolyl on immunologic indicators in patients with diffuse toxic goiter].
A study of system of cellular and humoral immunity, unspecific defense in 187 patients with diffuse toxic goiter before and after treatment with mercasolyl revealed that despite the clinical effect, the agent did not essentially influence the content and functional activity of T-lymphocytes. The effect was more favourable on the content of immunoglobulins, titer of antithyroid antibodies. This was observed in mild and average severe course of the disease. It is suggested that mercasolyl effects lymphocytes synthesizing autoantibodies to the thyroid gland.
Epishin
A V
AV
Solomko
L D
LD
Epishina
N A
NA
Kuz'mich
Iu P
IuP
D000328:Adult; D001323:Autoantibodies / Q000096:biosynthesis; D004359:Drug Therapy, Combination; D005260:Female; D006042:Goiter / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D008297:Male; D008713:Methimazole / Q000627:therapeutic use*; D008875:Middle Aged; D013961:Thyroid Gland / Q000276:immunology
D001323:Autoantibodies; D008713:Methimazole
Vliianie merkazolila na immunologicheskie pokazateli u bol'nykh diffuznym toksicheskim zobom.