title: Carcinogenicity of general-purpose phthalates: structure-activity relationships.
abstract: There does not appear to be any evidence that other GP phthalates pose higher-level risk than DEHP. There is evidence that a very significant fraction of GP phthalate production capacity is devoted to turning out products which may have about the same carcinogenic potency as DEHP, and that another significant fraction of that capacity is devoted to turning out products with less potency. Public and private risk control choice takers considering this family of products need to be aware of this evidence, its limitations, and the means for upgrading certainty.
authors.affiliation: U.S. Environmental Protection Agency, Washington, DC 20460.
authors.forename: J W
authors.initials: JW
authors.lastname: Hirzy
mesh_terms: D000818:Animals; D002273:Carcinogens; D004051:Diethylhexyl Phthalate / Q000633:toxicity; D006801:Humans; D010795:Phthalic Acids / Q000633:toxicity*; D013329:Structure-Activity Relationship
chemical_list: D002273:Carcinogens; D010795:Phthalic Acids; D004051:Diethylhexyl Phthalate