title: Elastase 1 and chymotrypsin B in pancreatic juice and feces.
abstract: A chymotrypsin-like protease was detected along with elastase 1 in pancreatic secretion and stool. This enzyme was isolated from necrobiotic human pancreas, purified, partially characterized and designated as chymotrypsin B. Quantitative studies by rocket immunoelectrophoresis indicated that neither elastase 1 nor chymotrypsin B was degraded during intestinal passage. On the basis of a clinical study, both enzymes were found to reflect pancreatic function.
authors.affiliation: Department of Gastroenterology, University of Giessen, FRG.
authors.forename: A
authors.initials: A
authors.lastname: Sziegoleit
authors.forename: E
authors.initials: E
authors.lastname: Krause
authors.forename: H U
authors.initials: HU
authors.lastname: Klör
authors.forename: L
authors.initials: L
authors.lastname: Kanacher
authors.forename: D
authors.initials: D
authors.lastname: Linder
mesh_terms: D002918:Chymotrypsin / Q000378:metabolism*; D004591:Electrophoresis, Polyacrylamide Gel; D005243:Feces / Q000201:enzymology*; D006801:Humans; D007122:Immunoelectrophoresis; D007700:Kinetics; D010196:Pancreatic Elastase / Q000378:metabolism*; D010189:Pancreatic Juice / Q000201:enzymology*
chemical_list: D002918:Chymotrypsin; D010196:Pancreatic Elastase