title: [Exchange plasmapheresis in combined treatment of severe uveitis].
abstract: Exchange plasmapheresis (EP) has been employed in multiple-modality therapy of 15 patients suffering from severe uveitis. The traditional therapy has yielded but a short-term effect and failed to stabilize the process in these patients. EP has resulted in improvement in all the patients: the injection has reduced, as well as the number of precipitates and oracities in the vitreous body; hemorrhages in the fundus oculi have resolved, and the vision acuity has considerably improved in 11 of the 15 patients; no cases of the deterioration of the vision acuity have been recorded. The relapses have ceased in 10 patients. EP has been well tolerated and yielded no complications; it has normalized the levels of the blood serum immunoglobulins and circulating immune complexes and activized phagocytosis.
authors.forename: O B
authors.initials: OB
authors.lastname: Chentsova
authors.forename: M P
authors.initials: MP
authors.lastname: Grechanyĭ
authors.forename: A V
authors.initials: AV
authors.lastname: Kil'diushevskiĭ
mesh_terms: D000328:Adult; D000936:Antigen-Antibody Complex / Q000032:analysis; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008297:Male; D008875:Middle Aged; D010587:Phagocytosis; D010956:Plasmapheresis; D014605:Uveitis / Q000276:immunology / Q000628:therapy*; D014792:Visual Acuity
chemical_list: D000936:Antigen-Antibody Complex; D007136:Immunoglobulins
vernacular_title: Obmennyĭ plazmaferez v kompleksnom lechenii tiazhelykh uveitov.