Early results of local application of 13-cis retinoic acid in the treatment of leukoplakia of the vulva.
A group of 35 patients with leukoplakia of the vulva was treated with 13-cis retinoic acid applied topically. Complete or partial remission occurred in 17 patients. Parallel determination of retinol level in sera revealed its increased value as compared to healthy persons.
Kwaśniewski
S W
SW
Cancer Center Maria Skłodowska Curie Institute - Warsaw, Poland.
Stelmachów
J
J
Janik
P
P
Kugaczewska
M
M
Sawicki
J
J
Golanek
M
M
D000287:Administration, Topical; D000328:Adult; D000368:Aged; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007971:Leukoplakia / Q000188:drug therapy* / Q000473:pathology; D008875:Middle Aged; D014212:Tretinoin / Q000008:administration & dosage* / Q000627:therapeutic use; D014846:Vulvar Neoplasms / Q000188:drug therapy* / Q000473:pathology
D014212:Tretinoin