Malignant schwannoma of the clitoris in a 1-year-old child.
A 1-year-old infant with von Recklinghausen's neurofibromatosis was seen because of increasing clitoral enlargement over a 7-month period. The mother, who also had neurofibromatosis, was treated 2 years beforehand for an acoustic neuroma. The child was treated by radical clitorectomy. Pathologic examination revealed malignant schwannoma, a tumor not previously described in this site. Vincristine, dactinomycin, and cyclophosphamide chemotherapy was given for 2 years to prevent local recurrence and metastatic spread. The child remains tumor free 2.5 years after diagnosis.
Thomas
W J
WJ
Department of Pediatrics, Naval Hospital, San Diego, California 92134-5000.
Bevan
H E
HE
Hooper
D G
DG
Downey
E J
EJ
D002987:Clitoris; D005260:Female; D005833:Genital Neoplasms, Female / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007223:Infant; D009442:Neurilemmoma / Q000188:drug therapy / Q000473:pathology*