[Immunoenzyme analysis with corpuscular antigen in the study of zoonotic cutaneous leishmaniasis].
Comparative study of sera from patients suffering from zoonotic cutaneous leishmaniasis by indirect immunofluorescence (IIF) and by enzyme immunoassay (ELISA) gave 72.4 and 89.6% positive results, correspondingly, with homologous antigen L. major. Good correlation of these methods was revealed--coincidence in 83% cases. Authors used ELISA with corpuscular Leishmania antigen. The test was superior to IIF in sensitivity and specificity. Creation of type-specific Leishmania test systems for ELISA opens new vistas in studies of the population immune structure in combined zoonotic cutaneous leishmaniasis and visceral leishmaniasis foci.
Goncharov
D B
DB
Gracheva
L I
LI
Saf'ianova
V M
VM
Dobrzhanskaia
R S
RS
Khuseĭinova
Kh Kh
KhKh
D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis; D000953:Antigens, Protozoan; D004797:Enzyme-Linked Immunosorbent Assay / Q000295:instrumentation / Q000379:methods; D004912:Erythrocytes / Q000276:immunology*; D005069:Evaluation Studies as Topic; D005455:Fluorescent Antibody Technique / Q000295:instrumentation; D006801:Humans; D007895:Leishmania tropica / Q000276:immunology*; D007896:Leishmaniasis / Q000175:diagnosis*
D000913:Antibodies, Protozoan; D000953:Antigens, Protozoan
Immunofermentnyĭ analiz s korpuskuliarnym antigenom pri izuchenii zoonoznogo kozhnogo leĭshmanioza.