An application of monoclonal antibodies to identification of leptospires of serogroup icterohaemorrhagiae found in China.
For the purpose of improving the procedures of identification of leptospires, a set of 5 monoclonal antibodies with different serological reactivity against serovars of Leptospira interrogans Icterohaemorrhagiae serogroup isolated in China was developed. One hundred and eight strains isolated from epidemic fields in 5 provinces in southern China were distinctly identified into 4 serovars of Icterohaemorrhagiae serogroup by the monoclonal antibody procedure, i.e., 98 isolates were identified as serovar lai, 7 as icterohaemorrhagiae, 2 as copenhageni, and 1 as H2. Factor antiserum procedure was used at the same time as control for typing these strains and an identical result was obtained.
Zhang
W H
WH
Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing.
Bai
X F
XF
Nie
D K
DK
Deng
Q D
QD
D000818:Animals; D000911:Antibodies, Monoclonal; D015373:Bacterial Typing Techniques; D002681:China; D007921:Leptospira interrogans / Q000145:classification*; D051379:Mice
D000911:Antibodies, Monoclonal