title: [A case of thrombotic thrombocytopenic purpura].
abstract: Thrombocytopenic thrombotic purpura is a comparatively rare disease and little is known about its aetiopathogenesis. Once almost invariably negative, the prognosis has been changed by the introduction of plasmapheresis. A particularly complex clinical case is described and a number of conclusions are drawn from it: 1) there is no criterion for opting for any particular therapeutic approach; 2) evaluation of the clinical response is the only criterion for monitoring the effectiveness of ongoing treatment; 3) plasmapheresis is proposed as the treatment of choice; 4) vincristine is a useful alternative in the treatment of recalcitrant cases.
authors.affiliation: Presidio Ospedaliero di Garbagnate Milanese, Divisione di Medicina Generale II.
authors.forename: M
authors.initials: M
authors.lastname: Meregalli
authors.forename: F
authors.initials: F
authors.lastname: Gambelli
authors.forename: G
authors.initials: G
authors.lastname: Torchio
authors.forename: M
authors.initials: M
authors.lastname: Bocchia
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D010956:Plasmapheresis; D011697:Purpura, Thrombotic Thrombocytopenic / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D012008:Recurrence; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D014750:Vincristine
vernacular_title: Considerazioni a proposito di un caso di porpora trombotica trombocitopenica.