title: [Morphobiophysical features of the duodenal mucosa in patients with duodenal ulcers].
abstract: Chronic duodenitis in patients with duodenal ulcer is characterized by substantial morphofunctional changes in the mucosa, decreased transmural potential difference and definite patterns of carbohydrate-containing biopolymer production, the initial changes being manifested as neutral glycoprotein hypersecretion with their subsequent diminished synthesis rates, followed by a more pronounced drop of sialo- and sulfoglycoprotein levels. A correlation was found between the severity of duodenitis, morphometric and histochemical parameters, and gastric pepsin secretion rates (hypersecretion). It is suggested that these changes are etiopathogenetically common.
authors.forename: G M
authors.initials: GM
authors.lastname: Mogil'naia
authors.forename: A A
authors.initials: AA
authors.lastname: Fisher
authors.forename: V V
authors.initials: VV
authors.lastname: Gorban'
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001704:Biopolymers; D002908:Chronic Disease; D004381:Duodenal Ulcer / Q000473:pathology*; D004382:Duodenitis / Q000473:pathology; D004386:Duodenum / Q000473:pathology*; D005260:Female; D006023:Glycoproteins / Q000032:analysis; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012795:Sialoglycoproteins / Q000032:analysis
chemical_list: D001704:Biopolymers; D006023:Glycoproteins; D012795:Sialoglycoproteins
vernacular_title: Morfobiofizicheskie osobennosti slizistoĭ obolochki dvenadtsatiperstnoĭ kishki u bol'nykh duodenal'noĭ iazvoĭ.