title: [Pesticide immunotoxicity].
abstract: Pesticides have been reported as altering immune functions in animals and man. The authors review published data from which it emerges that pesticide exposure is often associated with depressed humoral and cellular responses in mammals. The immunomodulating effects are affected by the route of administration and can also occur without general toxic effects, with a clear dose-effect correlation and for different dose levels. Immunotoxicity has also been investigated in workers occupationally exposed to pesticides: many kinds of effects are described, since many immunotoxicants have multiple effects on immune functions but the authors emphasize the importance of further studies carried out in workplace situations where exposure levels can be more accurately measured.
authors.forename: A
authors.initials: A
authors.lastname: Betta
authors.forename: G
authors.initials: G
authors.lastname: Maranelli
authors.forename: C
authors.initials: C
authors.lastname: Dal Ri
mesh_terms: D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects*; D009790:Occupations; D010575:Pesticides / Q000009:adverse effects*
chemical_list: D010575:Pesticides
vernacular_title: Immunotossicità da pesticidi.