title: [Influence of aminophylline on immune function of mice].
abstract: The effects of aminophylline (Ami) on immune systems in normal NIH mice were studied. Ami ig 25, 50 and 100 mg/(kg.d) x 8-10 d increased hemolytic ability of plaque forming cells and antibody concentration while it decreased the delayed type hypersensitivity (DTH) reaction and peripheral white blood cells phagocytosing function. Ami 1, 5, 10 micrograms/ml also promoted lymphocyte transformation of [methyl-3H] TdR incorporation induced by PHA in vitro.
authors.forename: F
authors.initials: F
authors.lastname: Liu
authors.forename: D
authors.initials: D
authors.lastname: Bian
authors.forename: H Q
authors.initials: HQ
authors.lastname: Zheng
authors.forename: R F
authors.initials: RF
authors.lastname: Cheng
mesh_terms: D000628:Aminophylline / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D005260:Female; D006462:Hemolytic Plaque Technique; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D051379:Mice; D010587:Phagocytosis / Q000187:drug effects
chemical_list: D000628:Aminophylline