title: Immunoprotection by beta-1,3 glucan antigen combination in Plasmodium berghei infection in mice.
abstract: In an attempt to protect mice against experimental infection with P. berghei, mice were immunized against soluble extract of P. berghei in combination with beta-1,3 glucan or FCA and also independently. Mice immunized against P. berghei antigen-glucan developed well defined cell mediated and humoral immune responses, while mice injected with antigen FCA or antigen alone developed only an antibody response. Antigen-glucan immunization afforded a high degree of immune protection to the host against the challenge with live parasites.
authors.forename: R
authors.initials: R
authors.lastname: Maheshwari
authors.forename: M U
authors.initials: MU
authors.lastname: Siddiqui
mesh_terms: D000276:Adjuvants, Immunologic; D000818:Animals; D000913:Antibodies, Protozoan / Q000096:biosynthesis; D000953:Antigens, Protozoan / Q000276:immunology*; D005936:Glucans / Q000276:immunology*; D007111:Immunity, Cellular; D008288:Malaria / Q000517:prevention & control*; D008297:Male; D051379:Mice; D010962:Plasmodium berghei / Q000276:immunology*; D047071:beta-Glucans
chemical_list: D000276:Adjuvants, Immunologic; D000913:Antibodies, Protozoan; D000953:Antigens, Protozoan; D005936:Glucans; D047071:beta-Glucans; C033363:beta-1,3-glucan