title: The prevention of nitrosomethylurea-induced mammary tumors by d-limonene and orange oil.
abstract: The monocyclic monoterpenoid d-limonene and its source, orange oil, were found to prevent rat mammary carcinomas induced by the direct-acting carcinogen nitrosomethylurea. This chemopreventive effect was limited to the promotion/progression stage in this carcinogenesis model.
authors.affiliation: Department of Human Oncology, University of Wisconsin-Madison 53792.
authors.forename: T H
authors.initials: TH
authors.lastname: Maltzman
authors.forename: L M
authors.initials: LM
authors.lastname: Hurt
authors.forename: C E
authors.initials: CE
authors.lastname: Elson
authors.forename: M A
authors.initials: MA
authors.lastname: Tanner
authors.forename: M N
authors.initials: MN
authors.lastname: Gould
mesh_terms: D000818:Animals; D053138:Cyclohexenes; D005260:Female; D000077222:Limonene; D008325:Mammary Neoplasms, Experimental / Q000139:chemically induced*; D008770:Methylnitrosourea / Q000037:antagonists & inhibitors*; D051381:Rats; D011920:Rats, Inbred WF; D013729:Terpenes / Q000494:pharmacology*; D013997:Time Factors
chemical_list: D053138:Cyclohexenes; D013729:Terpenes; D008770:Methylnitrosourea; D000077222:Limonene