HTLV-1 seroprevalence in AIDS patients and in HIV-1 seropositive and seronegative subjects at risk for AIDS in northern Italy.
Sera of 1023 subjects belonging to categories at risk for AIDS, positive for HIV-1, were tested for antibodies to human T-cell leukemia virus (HTLV-1) by ELISA, Western blotting, and radioimmunoprecipitation (RIP) assay. Sera of these subjects were positive for antibodies to HTLV-1 in a percentage of 18.54%. Nine out of 18 sera from patients with AIDS had antibodies to HTLV-1 (50%). Sera of 207 intravenous drug abusers and 64 homosexual males, seronegative for HIV-1, were tested for antibodies to HTLV-1 and 6.7% of intravenous drug abusers and 7.8% of homosexual males were found to be HTLV-1 antibody positive, showing that HTLV-1 infection occurred independently of HIV-1 and HIV-2 infections. In fact the same HIV-1 seronegative patients were also tested for the presence of antibodies to HIV-2 and none of them was found to be positive.
Manca
N
N
Istituto di Microbiologia, Università di Brescia, Italy.
Caruso
A
A
Bonfanti
C
C
Savoldi
E
E
Li Vigni
R
R
Pirali
F
F
Sapelli
P L
PL
Turano
A
A
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology* / Q000635:transmission; D015483:HIV Antibodies / Q000032:analysis*; D006679:HIV Seropositivity / Q000276:immunology* / Q000635:transmission; D015497:HIV-1 / Q000276:immunology*; D015481:HTLV-I Antibodies / Q000032:analysis*; D006716:Homosexuality; D015368:Human T-lymphotropic virus 1 / Q000276:immunology*; D006801:Humans; D007558:Italy; D012307:Risk Factors; D019966:Substance-Related Disorders / Q000276:immunology
D015483:HIV Antibodies; D015481:HTLV-I Antibodies