Effect of Y chromosome and H-2 complex derived from Japanese wild mouse on sperm morphology.
Segregation of sperm abnormality level and H-2 haplotypes was investigated in F2 hybrid males obtained from reciprocal crosses involving two B10.congenic strains carrying H-2 and the Y chromosome of Japanese wild mice: B10.MOL-OHM (H-2wm4, 23.1% of sperm abnormalities) and B10.MOL-OKB (H-2wm8, 11.1% of sperm abnormalities). In both types of crosses mean levels of abnormal spermatozoa were significantly higher for males typed as H-2wm4/H-2wm4 than for heterozygous H-2wm4/H-2wm8 or homozygous H-2wm8/H-2wm8. These results suggest that the gene for high sperm abnormality is linked to H-2 complex of the B10.MOL-OHM strain.
Suh
D S
DS
Styrna
J
J
Moriwaki
K
K
D000818:Animals; D006183:H-2 Antigens / Q000235:genetics*; D008297:Male; D009115:Muridae; D013094:Spermatozoa / Q000002:abnormalities*; D014998:Y Chromosome
D006183:H-2 Antigens