title: Influence of two quinolones, ofloxacin and pefloxacin, on human myelopoiesis in vitro.
abstract: The influence of ofloxacin and pefloxacin on human myelopoiesis in vitro was investigated. Drug concentrations varied from 0.5 to 50 micrograms/ml, and the effect on granulomonocyte precursors was evaluated on cell cultures in agar. Our results indicate that ofloxacin and pefloxacin do not induce inhibition of myelopoiesis.
authors.affiliation: Istituto di Clinica delle Malattie Infettive, Università Cattolica del Sacro Cuore, Rome, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Pallavicini
authors.forename: A
authors.initials: A
authors.lastname: Antinori
authors.forename: G
authors.initials: G
authors.lastname: Federico
authors.forename: M
authors.initials: M
authors.lastname: Fantoni
authors.forename: P
authors.initials: P
authors.lastname: Nervo
mesh_terms: D001854:Bone Marrow Cells; D002455:Cell Division / Q000187:drug effects; D006801:Humans; D015242:Ofloxacin / Q000494:pharmacology*; D015366:Pefloxacin / Q000494:pharmacology*
chemical_list: D015366:Pefloxacin; D015242:Ofloxacin