Nuclear and nucleolar changes in preimplantation mouse embryos expressing numerous virus-like particles.
Preimplantation mouse embryos spontaneously arrested in development at the two-cell and three-cell stages were obtained from a pregnant Slc: ICR mouse. Numerous intracisternal A-type virus-like particles were expressed in the cytoplasm of these abnormal mouse embryos. Several nuclear and nucleolar changes observed in these embryos, probably related to the hyperactive synthesis of virus-like particles, were reported.
Takeuchi
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D000818:Animals; D001755:Blastocyst / Q000382:microbiology / Q000648:ultrastructure*; D002466:Cell Nucleolus / Q000648:ultrastructure*; D002467:Cell Nucleus / Q000648:ultrastructure*; D003593:Cytoplasm / Q000382:microbiology; D051379:Mice; D008813:Mice, Inbred ICR; D008854:Microscopy, Electron; D014771:Virion / Q000648:ultrastructure*