Some aspects of Leucocytozoon caulleryi reinfection in chickens.
The role of first- and second-generation schizonts in acquired immunity to Leucocytozoon caulleryi in chickens was studied. The chickens, which had recovered from a primary infection with various doses of sporozoites at 22-95 days of age, were challenged with sporozoites. First-generation merozoites were found in all of the challenged chickens, but no second-generation merozoites and gametocytes were seen in 30 of 32 chickens challenged with sporozoites. Almost all of the chickens that had recovered from a primary infection with sporozoites showed complete resistance to reinfection, and those that had recovered from a primary infection with first-generation merozoites showed resistance to reinfection with sporozoites. These results indicate that the second-generation schizont of L. caulleryi appears to be more immunogenic than the first-generation schizont and that some immune factors acquired by the chickens in the second generation of schizogony may inhibit the development of second-generation schizonts.
Morii
T
T
Department of Parasitology, Kyorin University School of Medicine, Tokyo, Japan.
Matsui
T
T
Kobayashi
F
F
Iijima
T
T
D000818:Animals; D000913:Antibodies, Protozoan / Q000096:biosynthesis; D002645:Chickens / Q000469:parasitology*; D056890:Eukaryota / Q000254:growth & development / Q000276:immunology; D007110:Immunity, Active; D008297:Male; D011201:Poultry Diseases / Q000276:immunology* / Q000469:parasitology; D011528:Protozoan Infections / Q000276:immunology / Q000469:parasitology; D011529:Protozoan Infections, Animal; D012008:Recurrence
D000913:Antibodies, Protozoan