[The role of intracellular pool of polyamines in the regulation of metabolism in Escherichia coli during aerobic-anaerobic transitions].
The transition from aerobic to anaerobic conditions of Escherichia coli cultivation is accompanied by a drop in the free pool of putrescine in the cell as well as in the medium and by a decrease in the intracellular concentration of spermidine. This process stems from at least two facts: (1) the activity of ornithine decarboxylase, a key enzyme in the synthesis of polyamines, falls down due to a decrease in the level of ATP in the cell; (2) the free pool of polyamines is bound to cell compartments, in particular, to nucleoid DNA. The results make it possible to consider the system of polyamine synthesis as a point in the regulatory interaction between the energetic and constructive types of E. coli metabolism.
Tkachenko
A G
AG
Chudinov
A A
AA
Churilova
N S
NS
D000255:Adenosine Triphosphate / Q000378:metabolism; D000332:Aerobiosis; D000693:Anaerobiosis; D015317:Biogenic Polyamines / Q000378:metabolism*; D004926:Escherichia coli / Q000201:enzymology / Q000378:metabolism* / Q000648:ultrastructure; D008854:Microscopy, Electron; D009955:Ornithine Decarboxylase / Q000378:metabolism
D015317:Biogenic Polyamines; D000255:Adenosine Triphosphate; D009955:Ornithine Decarboxylase
Rol' vnutrikletochnogo pula poliaminov v reguliatsii konstruktivnogo obmena Escherichia coli v protsesse aérobno-anaérobnykh perekhodov.