title: Chemoprophylaxis of trypanosomiasis, due to Trypanosoma (Nannomonas) congolense, in rabbits using a slow release device containing homidium bromide.
abstract: The prophylactic activity of a subcutaneously implanted slow release device, containing homidium bromide, was assessed in rabbits, challenged with different stocks of T. congolense, and compared with the classical treatment of 1 mg homidium bromide/kg b.w. intramuscularly. The prophylactic activity of the intramuscular injection was less than a month, while the slow release device protected the rabbits against seven challenges with T. congolense during a period of more than 300 days.
authors.forename: R
authors.initials: R
authors.lastname: De Deken
authors.forename: S
authors.initials: S
authors.lastname: Geerts
authors.forename: P
authors.initials: P
authors.lastname: Kageruka
authors.forename: F
authors.initials: F
authors.lastname: Ceulemans
authors.forename: J
authors.initials: J
authors.lastname: Brandt
authors.forename: E
authors.initials: E
authors.lastname: Schacht
authors.forename: C
authors.initials: C
authors.lastname: Pascucci
authors.forename: C
authors.initials: C
authors.lastname: Lootens
mesh_terms: D000818:Animals; D002417:Cattle; D003692:Delayed-Action Preparations; D004996:Ethidium / Q000008:administration & dosage* / Q000627:therapeutic use; D011817:Rabbits / Q000469:parasitology; D014348:Trypanosoma congolense / Q000302:isolation & purification; D014354:Trypanosomiasis, Bovine / Q000517:prevention & control*
chemical_list: D003692:Delayed-Action Preparations; D004996:Ethidium