title: Carotid body tumours: the University of Alberta Hospital experience.
abstract: At the University of Alberta Hospital between 1950 and 1988, 17 patients who had a diagnosis of carotid body tumour were seen; 15 of them were followed up for an average of 8 years (range from 1 to 38 years). In 14 patients the tumour was removed surgically. There were no operative deaths and no strokes occurred. The most frequent complication was cranial nerve deficit. Of the 15 patients followed up, 10 (67%) manifested a deficit of the facial, vagus or hypoglossal nerve. The primary tumour was diagnosed histologically as a benign neoplasm in all 14 patients operated on, but in 3 distant metastases developed or there was invasive local recurrence. Patients with malignant tumour were significantly (p less than or equal to 0.01) younger than those with a benign tumour. Carotid body tumours can be managed safely with respect to stroke complications, but cranial nerve injuries continue to be a problem. Malignant tumours are difficult to distinguish from benign tumours except that they tend to occur in younger patients. Prompt surgery and close follow-up is particularly important in patients with carotid body tumour.
authors.affiliation: Department of Surgery, University of Alberta, Edmonton.
authors.forename: F A
authors.initials: FA
authors.lastname: Daudi
authors.forename: O G
authors.initials: OG
authors.lastname: Thurston
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000416:Alberta; D000792:Angiography; D001859:Bone Neoplasms / Q000556:secondary; D002345:Carotid Body Tumor / Q000175:diagnosis / Q000556:secondary / Q000601:surgery*; D020209:Cranial Nerve Injuries; D005260:Female; D005500:Follow-Up Studies; D006406:Hematoma / Q000209:etiology; D006785:Hospitals, University; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011183:Postoperative Complications