Estrogen replacement therapy (ERT) by a special regimen in the years following menopause.
A group of 16 post-menopausal women, mean age 56.6 years, with typical and non typical climacteric symptoms, were treated by a combination of estrogen (Premarin 0.625) followed by clomiphene citrate. Beside an improvement in musculo-skeletal pain and a marked improvement of their sense of well-being there was an increase in Hdl cholesterol, the protecting factor against M.I., while weight and blood pressure remained stable. The link between mood, sleep and libido improvement and catecholamine raise, is discussed, and so are the effects on blood pressure, in long lasting ERT.
Blum
M
M
Special Gynecological Outpatient Clinic, Tel Aviv University, Israel.
Zacharovitch
D
D
Pery
J
J
Gilerowitch
M
M
D001794:Blood Pressure / Q000187:drug effects; D002395:Catecholamines / Q000652:urine; D002996:Clomiphene / Q000494:pharmacology* / Q000627:therapeutic use; D004967:Estrogens / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D050356:Lipid Metabolism; D008593:Menopause / Q000187:drug effects*; D008875:Middle Aged
D002395:Catecholamines; D004967:Estrogens; D002996:Clomiphene