[Acute progressive respiratory insufficiency caused by diffuse interstitial pulmonary disease in a diabetic patient with dilated myocardiopathy].
This report describes the case of a 70-year-old female suffering from diabetes mellitus and dilatative cardiomyopathy with congestive heart failure. It is likely that alveolar-capillary membrane damage occurred apart from cardiac involvement. Diffuse interstitial pulmonary fibrosis subsequently occurred with consequent acute progressive respiratory failure and death. The cause of the damage to the alveolar-capillary membranes is still unknown and we thought that long-term administration of captopril might have contributed to the damage itself, since like all ACE-inhibitors, captopril is able to bring about tissular storage of both bradykinin and prostaglandins and therefore alter the pulmonary reactivity to phlogistic stimuli.
Savagnone
E
E
La Seta
F
F
Mauro
B
B
Occhipinti
G
G
Schirò
V
V
D000208:Acute Disease; D000368:Aged; D002311:Cardiomyopathy, Dilated / Q000150:complications*; D048909:Diabetes Complications; D005260:Female; D006333:Heart Failure / Q000150:complications; D006801:Humans; D011658:Pulmonary Fibrosis / Q000150:complications*; D012131:Respiratory Insufficiency / Q000209:etiology*
Insufficienza respiratoria acuta progressiva da interstiziopatia polmonare diffusa insorta in diabetica con miocardiopatia dilatativa.