The role for reactive oxygen species in cyclosporin A induced nephrotoxicity in rats.
Kumano
K
K
Department of Urology, Molecular Biology and Pathology, Kitasato University School of Medicine, Kanagawa, Japan.
Yoshida
K
K
Iwamura
M
M
Endo
T
T
Sakai
T
T
Nakamura
K
K
Kuwao
T
T
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D003524:Cyclosporins / Q000633:toxicity*; D006861:Hydrogen Peroxide / Q000378:metabolism*; D007668:Kidney / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology; D007672:Kidney Cortex / Q000378:metabolism; D008297:Male; D008314:Malonates / Q000378:metabolism*; D008315:Malondialdehyde / Q000378:metabolism*; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values
D000975:Antioxidants; D003524:Cyclosporins; D008314:Malonates; D008315:Malondialdehyde; D006861:Hydrogen Peroxide