Candida albicans shunt infection.
Seven cases of successfully treated Candida albicans cerebrospinal fluid shunt infections are reported. Treatment consisted of shunt removal and intravenous Amphotericin B in all cases and intraventricular Amphotericin B in 4 cases. Serious underlying medical illness, recent antibiotic therapy, indwelling intravascular and/or Foley catheters, coincident candidiasis and low birth weight prematurity are major risk factors for candida shunt infection. Candida shunt infection appears to occur by either contamination at the time of shunt placement or by hematogenous dissemination.
Shapiro
S
S
Department of Neurosurgery, Indiana University Medical Center, Indianapolis.
Javed
T
T
Mealey
J
J
D000293:Adolescent; D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D002177:Candidiasis / Q000188:drug therapy / Q000209:etiology*; D002408:Catheters, Indwelling; D002557:Cerebrospinal Fluid Shunts / Q000009:adverse effects*; D004866:Equipment Contamination; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D009894:Opportunistic Infections / Q000209:etiology*; D012307:Risk Factors; D018805:Sepsis / Q000150:complications / Q000188:drug therapy; D013530:Surgical Wound Infection / Q000188:drug therapy / Q000209:etiology
D000900:Anti-Bacterial Agents; D000666:Amphotericin B