[Effects of intrauterine alcohol intoxication on the function of the central nervous system in the progeny].
Behavior of mature rats, who had been exposed antenatally to intrauterine alcoholic intoxication, was studied in the open field settings, unavoidable swimming and Simonov's emotional resonance situations; their conditioned reflexes of passive and active avoidance were trained, arterial blood pressure was measured, and sleeping patterns examined. It was demonstrated that animals' orientation/exploration activity was reduced, while passive behavior and fear-associated emotions became more prominent, conditioned reflexes were more difficult to form, vegetative autoregulation was disturbed, and insomniac disturbances were in evidence as a result of intrauterine alcoholic intoxication. It is suggested that the above-listed disorders are rooted in hypoxic cerebral changes, induced by pathogenic effects of alcohol on the embryonal and fetal central nervous system.
Kolomeĭtseva
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Levina
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D000818:Animals; D001341:Autonomic Nervous System / Q000502:physiology; D001794:Blood Pressure; D001921:Brain / Q000502:physiology*; D003214:Conditioning, Classical; D005106:Exploratory Behavior; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders; D006706:Homeostasis; D008297:Male; D009949:Orientation; D011247:Pregnancy; D051381:Rats
Vliianie alkogol'noĭ intoksikatsii v period vnutriutrobnogo razvitiia na funktsii tsentral'noĭ nervnoĭ sistemy potomstva.