title: [Streptococcus-induced syndrome of toxic shock (streptococcal toxic shock syndrome)].
abstract: Report on the first case of streptococcal toxic shock syndrome in the GDR. The patient was a 54-year-old female. One week before admission to the hospital she cut her finger. The day before admission to the hospital she presented with a painful left shoulder. Demarcation followed, and Streptococcus pyogenes (group A streptococci) was isolated from this area. The temperature rose to more than 40 degrees C and she became confused, hypotensive and anuric. There was evidence for disseminated intravascular coagulation. She died 23 h after admission. Clinical course and laboratory parameters resembles staphylococcal toxic shock syndrome, except a diarrhoea. The streptococcal strain produced a large amount of erythrogenic toxin type B (more than 20 ng/ml), but not erythrogenic toxins A or C. Erythrogenic toxins of Streptococcus pyogenes seem to play the same role in the development of streptococcal toxic shock syndrome as the toxic shock syndrome 1 (TSST-1) in staphylococcal toxic shock syndrome.
authors.affiliation: Zentralinstitutes für Mikrobiologie und experimentelle Therapie Jena, DDR.
authors.forename: W
authors.initials: W
authors.lastname: Köhler
authors.forename: J
authors.initials: J
authors.lastname: Nestler
authors.forename: H
authors.initials: H
authors.lastname: Knöll
authors.forename: J
authors.initials: J
authors.lastname: Schneider
authors.forename: H P
authors.initials: HP
authors.lastname: Schau
mesh_terms: D000818:Animals; D001921:Brain / Q000473:pathology; D005260:Female; D005859:Germany, East; D006801:Humans; D007668:Kidney / Q000473:pathology; D008099:Liver / Q000473:pathology; D008168:Lung / Q000473:pathology; D051379:Mice; D008807:Mice, Inbred BALB C; D008875:Middle Aged; D009132:Muscles / Q000473:pathology; D009206:Myocardium / Q000473:pathology; D012772:Shock, Septic / Q000175:diagnosis* / Q000473:pathology; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000473:pathology; D013297:Streptococcus pyogenes / Q000472:pathogenicity; D014774:Virulence
vernacular_title: Streptokokkenbedingtes Syndrom des toxischen Schocks (Streptococcal Toxic Shock Syndrome).