[Complementary treatment with anti-inflammatory drugs in chronic periodontal disease].
Experimental studies have shown the ability of nonsteroidal anti-inflammatory drugs to reduce the rate of progression of alveolar bone destruction in animals with experimental periodontitis as a result of inhibition of biosynthesis of prostaglandin-sintetase metabolites. However, the long-term use of anti-inflammatory drugs in the treatment in periodontal disease requires confirmation of experimental results in long-term prospective and independent trials in humans, and elucidation and control of possible side effects due to the inhibition of prostaglandin-sintetase.
Mendieta Fiter
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Conde Vidal
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D000539:Alveolar Process / Q000473:pathology; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D001862:Bone Resorption / Q000188:drug therapy; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D010510:Periodontal Diseases / Q000188:drug therapy*; D011448:Prostaglandin Antagonists / Q000627:therapeutic use*; D051381:Rats
D000894:Anti-Inflammatory Agents, Non-Steroidal; D005938:Glucocorticoids; D011448:Prostaglandin Antagonists
Tratamiento coadyuvante con antiinflamatorios en la enfermedad periodontal crónica.