[Asbestos and bronchogenic carcinoma: a search for fibers in the pulmonary tissue of 3 patients with bronchogenic carcinoma].
Based on the highly suspicious radiological findings of exposure to asbestos (case 1) or on a positive occupational history (cases 2 and 3), the authors looked for the presence of fibers in blocks of lung tissue removed in autopsy or surgical biopsies of three cases of bronchogenic carcinoma. The blocks were submitted to sodium hypochloride digestion followed by fiber identification in phase contrast light microscopy. The authors were able to demonstrate the presence of fibres in the three cases. The likelyhood of those carcinomas being caused by exposure to asbestos is very high, as two out of the three cases showed pulmonary fibrosis (cases 1 and 2) and the other case showed typical parietal pleural plaques at thoracotomy.
Algranti
E
E
Lima
C Q
CQ
Vieira
A V
AV
D000368:Aged; D001194:Asbestos / Q000009:adverse effects / Q000302:isolation & purification*; D001195:Asbestosis / Q000150:complications; D002283:Carcinoma, Bronchogenic / Q000032:analysis* / Q000209:etiology / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000032:analysis* / Q000209:etiology / Q000473:pathology; D008297:Male; D008858:Microscopy, Phase-Contrast
D001194:Asbestos
Asbesto e carcinoma broncogênico: pesquisa de fibras em tecido pulmonar de três pacientes portadores de carcinoma broncogênico.