title: Sulfite sensitivity: relationship between sulfite plasma levels and bronchospasm: case report.
abstract: The present study describes a case of a 38-year-old nurse with asthma and probable sensitivity to sulfites. A double-blind challenge with sulfite and placebo was performed, pulmonary function tests were measured along with plasma levels of sulfites. A deficiency in sulfite-oxidase is suggested as the trigger mechanism of bronchospasm.
authors.affiliation: Allergy and Immunology Service, Hospital de Especialidades, México, DF.
authors.forename: R
authors.initials: R
authors.lastname: Acosta
authors.forename: J
authors.initials: J
authors.lastname: Granados
authors.forename: M
authors.initials: M
authors.lastname: Mourelle
authors.forename: V
authors.initials: V
authors.lastname: Perez-Alvarez
authors.forename: E
authors.initials: E
authors.lastname: Quezada
mesh_terms: D000328:Adult; D001249:Asthma / Q000139:chemically induced; D001986:Bronchial Spasm / Q000097:blood / Q000139:chemically induced*; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D006801:Humans; D008176:Lung Volume Measurements; D013447:Sulfites / Q000009:adverse effects* / Q000097:blood / Q000494:pharmacology; D013997:Time Factors
chemical_list: D013447:Sulfites; C005200:sodium metabisulfite