title: Effect of maternal avoidance of eggs, cow's milk and fish during lactation upon allergic manifestations in infants.
abstract: Atopic/allergic manifestations and skin-prick tests (SPT) to egg white, cow's milk (CM) and fish were evaluated during the first 18 months of life in two matched groups of infants with a family history of atopy/allergy. In one group (n = 65) the mothers had a diet free from eggs, CM and fish during the first 3 months postpartum, whereas the mothers in the other group (n = 50) consumed an ordinary diet. The diet of the infants was similar in both groups, i.e. CM was not supplied until 6 months of age, and eggs and fish not until 9 months of age. The incidence of atopic dermatitis was significantly lower in the maternal diet group during the first 6 months postpartum (10.8 and 28%, respectively) but not after that age. Other atopic/allergic manifestations did not differ and the number of positive SPT to egg white, CM or fish at 9 months of age was similar in both groups.
authors.affiliation: Department of Pediatrics, Central Hospital, Skövde, Sweden.
authors.forename: G
authors.initials: G
authors.lastname: Hattevig
authors.forename: B
authors.initials: B
authors.lastname: Kjellman
authors.forename: N
authors.initials: N
authors.lastname: Sigurs
authors.forename: B
authors.initials: B
authors.lastname: Björkstén
authors.forename: N I
authors.initials: NI
authors.lastname: Kjellman
mesh_terms: D000818:Animals; D001249:Asthma / Q000209:etiology; D001942:Breast Feeding; D003876:Dermatitis, Atopic / Q000209:etiology*; D015387:Egg Proteins, Dietary / Q000008:administration & dosage*; D005260:Female; D005399:Fishes; D005512:Food Hypersensitivity / Q000209:etiology*; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology*; D007073:Immunoglobulin E / Q000032:analysis; D007223:Infant; D007225:Infant Food; D007231:Infant, Newborn; D007774:Lactation; D008892:Milk; D011247:Pregnancy
chemical_list: D015387:Egg Proteins, Dietary; D007073:Immunoglobulin E