title: Lack of correlation between milk glucose concentrations and rates of milk production in the rat.
abstract: Concentrations of lactose, alpha-lactalbumin (alpha-la), glucose and glucose-6-phosphate were measured in milk obtained from rats under conditions where the rates of milk production varied from 0 to 2.6 g/h. In the milk from rats fed a low protein diet where milk production was 0.9 g/h, the concentration of alpha-la was 1.5 mg/ml, being significantly lower than that in the milk of control rats at 2.9 mg/ml and where the rate of milk production was 2.6 g/h. No differences were detected in the glucose concentrations. When rats were fed restricted amounts of the control diet and where milk production varied from 0 to 1.7 g/h during the course of the day, no differences in the concentrations of either alpha-la or glucose were detected. These results suggest that considerable caution must be used in interpreting the significance of milk glucose in the rat.
authors.affiliation: Department of Biochemistry, University of Otago, Dunedin, New Zealand.
authors.forename: M R
authors.initials: MR
authors.lastname: Grigor
authors.forename: J M
authors.initials: JM
authors.lastname: Carrington
authors.forename: P G
authors.initials: PG
authors.lastname: Arthur
authors.forename: P E
authors.initials: PE
authors.lastname: Hartmann
mesh_terms: D000818:Animals; D005260:Female; D005947:Glucose / Q000032:analysis* / Q000378:metabolism; D019298:Glucose-6-Phosphate; D005958:Glucosephosphates / Q000032:analysis / Q000378:metabolism; D007768:Lactalbumin / Q000032:analysis / Q000378:metabolism; D007774:Lactation / Q000378:metabolism*; D007785:Lactose / Q000032:analysis / Q000378:metabolism; D008892:Milk / Q000032:analysis*; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D005958:Glucosephosphates; D019298:Glucose-6-Phosphate; D007768:Lactalbumin; D005947:Glucose; D007785:Lactose