Total fatty acids of hair lipids in cystic fibrosis.
In a preliminary study, total fatty acids of lipids removed from hair of subjects of either sex with cystic fibrosis (n = 17; average age 8.3 years) and controls (n = 24; average age 9.1 years) were analyzed by gas chromatography. In contrast to the blood lipids in cystic fibrosis which display various fatty acid changes as a depression in 18:2 and increases in 16:0, 16:1, and 18:1, such profiles did not occur with the hair lipids. With the latter, total fatty acids in cystic fibrosis showed decrements in 18:1 and in the lesser concentrations of 20:1 and members below C14 as compared to the respective control series.
Gershbein
L L
LL
Northwest Institute for Medical Research, Chicago, Illinois 60634.
Lloyd-Still
J D
JD
Rimkus
W V
WV
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000378:metabolism*; D005227:Fatty Acids / Q000032:analysis*; D005260:Female; D006197:Hair / Q000032:analysis*; D006801:Humans; D008055:Lipids / Q000032:analysis*; D008297:Male
D005227:Fatty Acids; D008055:Lipids