title: [Abnormal hemoglobins in Negroid Ecuadorian populations].
abstract: The prevalence of hemoglobinopathies was determined in the black race located in two distinct geographical areas in Ecuador; in the coastal province of Esmeraldas, particularly the Santiago basin (Rio Cayapas and Rio Onzoles) and in the province of Imbabura, particularly in the intermoutain valley, Valle de Chota. A total of 2038 blood samples were analyzed, 1734 in Esmeraldas and 304 in Inbabura, of which 23.2% (473 individuals) were found to be carriers of abnormal hemoglobins, 25.4% (441) in Esmeraldas and 10.5% (32) in Imbabura. The abnormal hemoglobins found in Esmeraldas were Hb AS (19.2%), Hb AC (5.0%), Hb SS (0.6%) and Hb SC (0.5%) while in Imbabura only Hb AS (9.5%) and Hb AC (0.9%) were found. The factors that could influence the difference in prevalence found in the two geographical areas are discussed.
authors.forename: N O
authors.initials: NO
authors.lastname: Jara
authors.forename: A
authors.initials: A
authors.lastname: Guevara Espinoza
authors.forename: R H
authors.initials: RH
authors.lastname: Guderian
mesh_terms: D044383:Black People / Q000235:genetics*; D004484:Ecuador; D005843:Geography; D006444:Hemoglobin C / Q000032:analysis; D006451:Hemoglobin, Sickle / Q000032:analysis; D006453:Hemoglobinopathies / Q000453:epidemiology / Q000208:ethnology* / Q000235:genetics; D006455:Hemoglobins, Abnormal / Q000032:analysis*; D006801:Humans
chemical_list: D006451:Hemoglobin, Sickle; D006455:Hemoglobins, Abnormal; C032001:hemoglobin D; D006444:Hemoglobin C
vernacular_title: Investigación de hemoglobinas anormales en poblaciones ecuatorianas de raza negra.