title: [Acute progressive respiratory insufficiency caused by diffuse interstitial pulmonary disease in a diabetic patient with dilated myocardiopathy].
abstract: This report describes the case of a 70-year-old female suffering from diabetes mellitus and dilatative cardiomyopathy with congestive heart failure. It is likely that alveolar-capillary membrane damage occurred apart from cardiac involvement. Diffuse interstitial pulmonary fibrosis subsequently occurred with consequent acute progressive respiratory failure and death. The cause of the damage to the alveolar-capillary membranes is still unknown and we thought that long-term administration of captopril might have contributed to the damage itself, since like all ACE-inhibitors, captopril is able to bring about tissular storage of both bradykinin and prostaglandins and therefore alter the pulmonary reactivity to phlogistic stimuli.
authors.forename: E
authors.initials: E
authors.lastname: Savagnone
authors.forename: F
authors.initials: F
authors.lastname: La Seta
authors.forename: B
authors.initials: B
authors.lastname: Mauro
authors.forename: G
authors.initials: G
authors.lastname: Occhipinti
authors.forename: V
authors.initials: V
authors.lastname: Schirò
mesh_terms: D000208:Acute Disease; D000368:Aged; D002311:Cardiomyopathy, Dilated / Q000150:complications*; D048909:Diabetes Complications; D005260:Female; D006333:Heart Failure / Q000150:complications; D006801:Humans; D011658:Pulmonary Fibrosis / Q000150:complications*; D012131:Respiratory Insufficiency / Q000209:etiology*
vernacular_title: Insufficienza respiratoria acuta progressiva da interstiziopatia polmonare diffusa insorta in diabetica con miocardiopatia dilatativa.