Bilateral adrenal phaeochromocytomas associated with unilateral renal artery stenosis.
A 21 year old male was discovered to be severely hypertensive. He was found to have bilateral adrenal phaeochromocytomas and a single renal artery stenosis. More than 40 cases of coexisting renal artery stenosis and phaeochromocytomas have been reported. The aetiology of renal artery stenosis in association with phaeochromocytoma maybe multifactorial and the radiographic appearances are not always clear-cut. Renin levels in this patient were elevated prior to the removal of the phaeochromocytomas but the renal vein renin ratio did not suggest that the renal artery stenosis contributed significantly to his hypertension. The patient's hypertension resolved following successful removal of the phaeochromocytomas despite persistence of the renal artery stenosis. Thus, though renin levels may be misleading in these cases, renal vein renin ratios may still be helpful in deciding on patient management.
Burns
A P
AP
Department of Medicine, Regional Hospital, Cork, Ireland.
O'Connell
P R
PR
Murnaghan
D J
DJ
Brady
M P
MP
D000310:Adrenal Gland Neoplasms / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging; D000328:Adult; D000792:Angiography; D006801:Humans; D006978:Hypertension, Renovascular / Q000209:etiology*; D008297:Male; D010673:Pheochromocytoma / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging; D012078:Renal Artery Obstruction / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging; D012083:Renin / Q000097:blood
D012083:Renin