Reversible cholestatic hepatitis caused by acetohexamide.
We report a case of cholestatic hepatitis accompanied by peripheral and hepatic eosinophilia in a patient taking acetohexamide for a period of 1.5 yr. Jaundice developed acutely and was accompanied by fever. After discontinuation of the drug, there was no evidence of further damage, with prompt normalization of liver enzymes, bilirubin, and eosinophil count.
Rank
J M
JM
University of Minnesota Hospital, Minneapolis.
Olson
R C
RC
D000092:Acetohexamide / Q000009:adverse effects*; D000368:Aged; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D002780:Cholestasis, Intrahepatic / Q000139:chemically induced; D005260:Female; D006801:Humans
D000092:Acetohexamide