[Evaluation of erythrocyte deformability in carriers of thalassemic trait with the Hanss' hemorheometer].
Red-cell deformability was assessed with the Hanss' haemorheometer in 63 carriers of the thalassaemic trait (20 beta and 43 delta beta). Impaired deformability (rigidity index 10.5 +/- 1.4) was present in 80% of the carriers of both beta- and delta beta-traits, as compared with a control group (rigidity index 8.7 +/- 0.6). No correlation was found between such indices and several parameters capable of influencing upon red-cell deformability, namely, MCV, MCH, RDW and MDA. The possibility of any impairment of lipid compounds in red cell membrane is suggested as a cause of decreased deformability in thalassaemia carriers.
Vayá
A
A
Mira
Y
Y
Martínez
M
M
Miralles
F
F
Aguado
C
C
Aznar
J
J
D000293:Adolescent; D000328:Adult; D002353:Carrier State; D002648:Child; D002675:Child, Preschool; D004907:Erythrocyte Deformability; D004913:Erythrocytes, Abnormal / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008315:Malondialdehyde / Q000502:physiology; D008875:Middle Aged; D012212:Rheology / Q000295:instrumentation*; D013789:Thalassemia / Q000097:blood* / Q000235:genetics
D008315:Malondialdehyde
Valoración de la deformabilidad eritrocitaria en portadores del rasgo talasémico con el hemorreómetro de Hanss.