[Use of fosfomycin tablets in the treatment of purulent skin diseases].
Fourteen patients with purulent skin diseases were treated orally with fosfomycin (FOM) 1.5-3 g in the tablet form for 1 week to determine its efficacy and safety. The results obtained are summarized as follows. 1. The clinical efficacy rate was 71.4%. A bacteriological eradication rate of 71.4% was obtained. 2. As adverse reactions 3 patients experienced diarrhea and abdominal pain. But in all of these patients, symptoms were relieved with a reduction in dosage. 3. Taking the efficacy and the safety into account, utility rate was assessed to be 71.4%. From these results it is considered that FOM tablets are useful equally to conventional FOM capsules.
Takahashi
H
H
Department of Dermatology, National Defense Medical College.
Kimura
Y
Y
Hiruma
M
M
Kukita
A
A
D000293:Adolescent; D000328:Adult; D000368:Aged; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D002214:Capsules; D003967:Diarrhea / Q000139:chemically induced; D004341:Drug Evaluation; D005260:Female; D005578:Fosfomycin / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000139:chemically induced; D012874:Skin Diseases, Infectious / Q000188:drug therapy* / Q000382:microbiology; D013607:Tablets
D002214:Capsules; D013607:Tablets; D005578:Fosfomycin