[Adrenal incidentaloma--report of 14 operated cases and analysis of 4-year autopsy series of Japan].
During the last 7 years, operation was performed for 94 cases of adrenal tumor in our series, of which 14 were incidentally found by abdominal computed tomography or echography. They included 9 cases of pheochromocytoma, 1 of Cushing's syndrome, 3 of ganglioneuroma and 1 of cortical adenoma. Five of 9 pheochromocytoma cases were devoid of hypertension, but all 9 cases had abnormally high levels of urinary catecholamines and/or their metabolites. The 4-year autopsy series of Japan (1980-1983) included about 153,000 cases. Except the metastatic tumors, the following lesions were incidentally found in the adrenal gland: 310 of cortical adenoma, 153 of cortical hyperplasia, 39 of pheochromocytoma and 17 cases of neurogenic tumors. Some of the cortical adenomas are presumed to be more than 1 cm in diameter. So, they are expected to be found incidentally, more frequently in the future. Surgery is not necessary for most of them, except for functioning tumors. Most of the pheochromocytomas are presumed to be hormonally active, and should be treated surgically. It is probable that these functioning tumors had been missed clinically, especially in the elderly persons. Neurogenic tumors and myelolipomas may be left in place, when malignancy can be ruled out.
Kawano
M
M
Department of Endocrine Surgery, Tokyo Women's Medical College, Japan.
Kodama
T
T
Ito
Y
Y
Obara
T
T
Fujimoto
Y
Y
D000236:Adenoma / Q000473:pathology*; D000306:Adrenal Cortex Neoplasms / Q000473:pathology; D000310:Adrenal Gland Neoplasms / Q000473:pathology* / Q000601:surgery; D005729:Ganglioneuroma / Q000473:pathology*; D006801:Humans; D010673:Pheochromocytoma / Q000473:pathology* / Q000601:surgery