A der(11)t(8;11) in two medulloblastomas. A possible nonrandom cytogenetic abnormality.
Cytogenetic analysis of tumor tissue from two patients with medulloblastoma is reported. Both showed the presence of an i(17q) and a der(11)t(8;11)(q11;p11). It is suggested that the t(8;11) may be a translocation associated with medulloblastoma.
Callen
D F
DF
Department of Histopathology, Adelaide Children's Hospital, South Australia.
Cirocco
L
L
Moore
L
L
D002528:Cerebellar Neoplasms / Q000235:genetics* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D002880:Chromosomes, Human, Pair 11; D002898:Chromosomes, Human, Pair 8; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D008527:Medulloblastoma / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic