title: Temporal arteritis revealed by upper limb gangrene.
abstract: An 80-year-old white man presented with gangrenous lesions involving several distal phalanges of his left hand and an elevated erythrocyte sedimentation rate (ESR). Temporal artery biopsy showed patchy destruction of the internal elastic lamina by mononuclear cell infiltration, consistent with the diagnosis of temporal arteritis. After amputation of gangrenous lesions, he was discharged taking prednisone (60 mg/day). Twelve months after discharge there was no recurrence of ischemic manifestations and ESR was normal. Association of digital gangrene and elevated ESR should alert the clinician toward this diagnosis once other diseases such as atherosclerosis, scleroderma, lupus erythematosus, periarteritis nodosa have been ruled out.
authors.affiliation: Service de Médecine Interne, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: de Gennes
authors.forename: D
authors.initials: D
authors.lastname: Le Thi Huong
authors.forename: B
authors.initials: B
authors.lastname: Wechsler
authors.forename: J
authors.initials: J
authors.lastname: Bercy
authors.forename: J F
authors.initials: JF
authors.lastname: Foncin
authors.forename: J C
authors.initials: JC
authors.lastname: Piette
authors.forename: P
authors.initials: P
authors.lastname: Godeau
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005385:Fingers / Q000473:pathology* / Q000601:surgery; D005734:Gangrene; D013700:Giant Cell Arteritis / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male