Computers: the best friends a human genome ever had.
Mapping and sequencing the human genome will generate large amounts of data, which must be sorted, analyzed, and stored for rapid retrieval to complete this enormous task. Computers and their software programs provide the most important tool to the molecular biologist today. A discussion of current capabilities and future needs in computer hardware and software for the human genome project is the topic of this paper. The use of computer programs to generate restriction maps, manage clone libraries, manage sequence projects, and generate consensus sequences is presented. The use of computers to communicate useful information rapidly to scientific colleagues is also mentioned. The role of both GenBank and BIONET is central to the dissemination and analysis of sequence information. The capabilities of electronic communication worldwide for assisting this project is available on the BIONET National Computer Resource, using existing networks.
Kelly
M J
MJ
IntelliGenetics, Inc., Mountain View, CA 94040.
D001483:Base Sequence; D002874:Chromosome Mapping; D003195:Computer Communication Networks; D003201:Computers; D005822:Genetic Vectors; D016045:Human Genome Project; D006801:Humans; D008969:Molecular Sequence Data; D009710:Nucleotide Mapping; D010957:Plasmids; D015183:Restriction Mapping; D012984:Software