Ovarian superstimulation in the treatment of infertility due to peritubal and periovarian adhesions.
Forty-two women with peritubal and periovarian adhesions as the only cause of infertility were superstimulated with clomiphene citrate and human menopausal gonadotropin in 103 cycles. Superstimulation resulted in considerable increase in ovarian size, and change in the tubo-ovarian relationship. Twenty-two patients became pregnant, achieving a pregnancy rate of 21% per cycle and an overall rate of 52%. Hyperstimulation syndrome occurred in 85 cycles (82.5%). Four cases of tubal pregnancy were reported (3.8%). This line of treatment could be tried before resorting to microsurgery or in vitro fertilization and embryo transfer in patients with peritubal and periovarian adhesions with at least one patent tube.
Aboulghar
M A
MA
Department of Obstetrics and Gynecology, Cairo University, Egypt.
Mansour
R T
RT
Serour
G I
GI
D000328:Adult; D006063:Chorionic Gonadotropin / Q000009:adverse effects / Q000627:therapeutic use*; D002996:Clomiphene / Q000009:adverse effects / Q000627:therapeutic use*; D005187:Fallopian Tubes; D005260:Female; D005831:Genital Diseases, Female / Q000150:complications; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy* / Q000209:etiology; D007986:Luteinizing Hormone / Q000652:urine; D010049:Ovarian Diseases / Q000139:chemically induced / Q000145:classification / Q000150:complications*; D010053:Ovary / Q000503:physiopathology*; D011247:Pregnancy; D013577:Syndrome; D000267:Tissue Adhesions / Q000150:complications*
D006063:Chorionic Gonadotropin; D002996:Clomiphene; D007986:Luteinizing Hormone