title: [A new cell line of rat gasserian ganglion neurinoma NGUK-1].
abstract: A new cell line has been derived from the rat gasserian ganglion neurinoma NGUK-1 induced by transplacental administration of ethylnitrosourea. It is characterized by an astrocyte-like growth pattern at the low cell density, and by an epitheliocyte-like pattern in the confluent monolayer. The cell line displays a high proliferative activity, its maximum mitotic index and proliferative pool being--2.5 and 96%, respectively. The chromosome number ranges between 20 to 100. The chromosome modal number is 39--44. The new cell line has been used for the express diagnostic of rabies, for determination of serum glial toxicity in neurologic patients, and interferon titration.
authors.forename: A P
authors.initials: AP
authors.lastname: Avtsyn
authors.forename: L I
authors.initials: LI
authors.lastname: Kondakova
authors.forename: A S
authors.initials: AS
authors.lastname: Khalanskiĭ
authors.forename: G P
authors.initials: GP
authors.lastname: Poliakova
authors.forename: N V
authors.initials: NV
authors.lastname: Chudinovskaia
mesh_terms: D000818:Animals; D001345:Autoradiography; D002460:Cell Line; D002875:Chromosomes / Q000648:ultrastructure; D005038:Ethylnitrosourea; D005726:Ganglia, Parasympathetic; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D008938:Mitosis; D009368:Neoplasm Transplantation; D009442:Neurilemmoma / Q000139:chemically induced / Q000648:ultrastructure*; D051381:Rats; D014407:Tumor Cells, Cultured
chemical_list: D005038:Ethylnitrosourea
vernacular_title: Novaia kletochnaia liniia nevrinomy gasserova uzla krysy NGUK-1.