title: [Aspects of organ-specific autoimmunity in cluster headache].
abstract: Fourty-eight cluster headache patients have been studied. Twenty-nine of them were affected also by rhythm cardiac abnormalities, and the other 19 by associated conjunctival hyperaemia. The presence of organ-specific autoantibodies was investigated by immunofluorescence. High titers of antibodies against cardiac antigenic determinants was found. The study of leukocyte subpopulations revealed a parallel increase in blood and in conjunctival mucosa of Leu7+ and LeuM3+ cells. These outcomes confirm the immunopathological theory of cluster headache.
authors.forename: M
authors.initials: M
authors.lastname: Giacovazzo
authors.forename: F
authors.initials: F
authors.lastname: Di Sabato
authors.forename: L
authors.initials: L
authors.lastname: Ruggieri
authors.forename: P
authors.initials: P
authors.lastname: Martelletti
mesh_terms: D001323:Autoantibodies / Q000032:analysis*; D003027:Cluster Headache / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D006801:Humans; D009928:Organ Specificity; D014653:Vascular Headaches / Q000276:immunology*
chemical_list: D001323:Autoantibodies
vernacular_title: Aspetti autoimmunitari organo-specifici della cefalea a grappolo.