Reflections of low calcium epileptiform activity from area CA1 into dentate gyrus in the rat hippocampal slice.
Lowering of [Ca2+]o induces epileptiform activity in hippocampal area CA1, characterized by slow negative field potentials with superimposed trains of population spikes and by rises in [K+]o. In dentate gyrus slow positive field potentials occur simultaneously with the activity in area CA1. The accompanying small rises in [K+]o may stem from spatial K+ redistribution through glial cells from area CA1.
Albrecht
D
D
Institut für Physiologie und Pathophysiologie, Universität zu Köln, Cologne, F.R.G.
Rausche
G
G
Heinemann
U
U
D000200:Action Potentials; D000818:Animals; D002118:Calcium / Q000502:physiology*; D006624:Hippocampus / Q000378:metabolism / Q000503:physiopathology*; D066298:In Vitro Techniques; D011188:Potassium / Q000502:physiology; D051381:Rats; D012640:Seizures / Q000378:metabolism*
D011188:Potassium; D002118:Calcium