Metabolism of glycoconjugates in human gastric mucosa a review.
Glycoconjugates, viz. glycoproteins, glycolipids and proteoglycans, play an important role in the protection of human gastric mucosa against pepsin and hydrochloric acid. The biosynthesis and catabolism of these compounds in the human gastric mucosa have been studied. We isolated and identified the majority of the intermediates and isolated some enzymes, taking part in the biosynthesis of glycoconjugates in the human gastric mucosa, and have demonstrated that the human gastric mucosa is able to release reducing sugars from glycoconjugates and shows some glycosidase activity.
Zwierz
K
K
Department of General and Organic Chemistry, Medical Academy, Białystok, Poland.
Gindzienski
A
A
Ostrowska
L
L
Stankiewicz-Choroszucha
B
B
D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D005753:Gastric Mucosa / Q000378:metabolism*; D006001:Glycoconjugates / Q000378:metabolism*; D006017:Glycolipids / Q000378:metabolism; D006023:Glycoproteins / Q000378:metabolism; D006801:Humans; D008969:Molecular Sequence Data; D011509:Proteoglycans / Q000378:metabolism
D006001:Glycoconjugates; D006017:Glycolipids; D006023:Glycoproteins; D011509:Proteoglycans