title: The dissolution of urinary mucus after cystoplasty.
abstract: Three agents have been tested for mucolytic activity to prevent or treat difficulties in bladder emptying following augmentation and substitution cystoplasty, particularly in patients emptying by intermittent self-catheterisation. Carbocysteine produced precipitation of mucus, which was found not to be helpful. N-acetylcysteine and urea both dissolved mucus, but urea proved to be more effective.
authors.affiliation: Department of Surgery and Urology, Guy's Hospital, London.
authors.forename: G
authors.initials: G
authors.lastname: Gillon
authors.forename: A R
authors.initials: AR
authors.lastname: Mundy
mesh_terms: D000111:Acetylcysteine / Q000627:therapeutic use; D002233:Carbocysteine / Q000627:therapeutic use; D005100:Expectorants / Q000627:therapeutic use*; D006801:Humans; D066298:In Vitro Techniques; D009093:Mucus / Q000187:drug effects*; D011183:Postoperative Complications / Q000188:drug therapy*; D014508:Urea / Q000627:therapeutic use; D001743:Urinary Bladder / Q000601:surgery*; D014556:Urine / Q000032:analysis*
chemical_list: D005100:Expectorants; D002233:Carbocysteine; D014508:Urea; D000111:Acetylcysteine