[Antibiotic prevention with a single dose of metronidazole in appendectomy in children].
One hundred children were prophylactically treated with 15 mg/kg-1 of metronidazole immediately before appendicectomy and retrospectively compared with 100 other patients without any antibioprophylaxis. No statistically significant difference was found between the two groups as regards age, weight, sex and macroscopic appearance of the appendix. The overall incidence of complications was 1% in the antibioprophylactic group and 9% in the control group. Furthermore, a single pre-operative intravenous dose of metronidazole was as effective as conventional antibioprophylaxis.
Lansade
A
A
Terrier
G
G
Longis
B
B
Moulies
D
D
Alain
J L
JL
Fouillard
A
A
D001062:Appendectomy / Q000009:adverse effects; D002648:Child; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage*; D011292:Premedication
D008795:Metronidazole
Antibioprophylaxie par dose unique de métronidazole pour appendicectomie chez l'enfant.