[Ultrastructure and immunologic pathology of membranous glomerulonephritis of 91 cases].
91 cases of membranous glomerulonephritis were investigated with light, electron and immunofluorescence microscopy. The findings indicated that 12 of 91 renal biopsies in membranous glomerulonephritis showed mesangial cell proliferation in various extent. The mesangial cell proliferation, segmental sclerosis and glomerular capillary adhesion to Bowmen's capsule were related to the stages and evolution of membranous glomerulonephritis. Granular immunofluorescence staining for IgG was a consistent finding, but the positive rate of C3 was lower than that of IgG. The relationship of immunofluorescence between different stages of membranous glomerulonephritis was not significant. In some cases, the subepithelial deposits were partially resorbed in stage 2 or stage 3, suggesting that early stage membranous glomerulonephritis could recover or turn to a favorable condition.
Zhou
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D000328:Adult; D002455:Cell Division; D005260:Female; D005455:Fluorescent Antibody Technique; D005920:Glomerular Mesangium / Q000473:pathology; D015433:Glomerulonephritis, Membranous / Q000473:pathology*; D006801:Humans; D007668:Kidney / Q000648:ultrastructure; D008297:Male