Hemoperfusion effect on oxygen-carrying function of preserved donor blood and erythrocytic mass.
The purpose of the study was to explore the preserved (7-21 days) donor blood and erythrocytic mass, following perfusion through hemosorbent SKN-D. After the sorption the oxygen-transport function of erythrocytes was found to improve considerably (oxyhemoglobin dissociation curve was shifted to the right on average by 4-4.2 mm Hg). The energy supply became better (ATP level was increased by 38-59%). In view of the above, long-preserved blood and erythrocytic mass following their perfusion through SKN-D hemosorbent can be considered a sufficiently valid transfusion medium.
Khodas MYa
Kavetsky Institute for Oncology Problems Ukr. SSR AS, All-Union Scientific Surgical Center USSR AMS.
Belkin
A L
AL
Mosolova
L A
LA
Povzhitkova
M S
MS
Leonova
S F
SF
Penkrak
K A
KA
Grischenko
M N
MN
Pyatnitskaya
G K
GK
D001692:Biological Transport; D001790:Blood Physiological Phenomena; D001793:Blood Preservation; D004912:Erythrocytes / Q000166:cytology / Q000378:metabolism*; D006464:Hemoperfusion; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010100:Oxygen / Q000378:metabolism*
D010100:Oxygen