An evidence of 'post-seizure excitation' in feline-kindled seizures.
We assessed the post-seizure effects on the seizure threshold and the seizure duration using low-frequency kindling technique. The number of stimulating pulses required for a triggering of epileptic afterdischarge (pulse-number threshold; PNT) was used for the indicator of seizure threshold. PNT increased significantly at 2 and 4 h inter-stimulation intervals, whereas it decreased significantly with an increase of seizure duration at 16 and 24 h intervals. It appears from these data that a post-seizure excitation occurs after a post-seizure inhibition.
Minabe
Y
Y
Department of Neuropsychiatry, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan.
Emori
K
K
Kurachi
M
M
D000200:Action Potentials; D000679:Amygdala / Q000503:physiopathology*; D000818:Animals; D002415:Cats; D005260:Female; D006624:Hippocampus / Q000503:physiopathology*; D007696:Kindling, Neurologic; D008297:Male; D012640:Seizures / Q000503:physiopathology*