Biosynthesis of the two halobacterial light sensors P480 and sensory rhodopsin and variation in gain of their signal transduction chains.
The two retinal-containing photoreceptors of halobacteria, P480 and sensory rhodopsin, are formed constitutively and inducibly, respectively. Both photoreceptors are synthesized as apoproteins in cells with nicotine-inhibited retinal synthesis and are reconstituted as chromoproteins by the addition of all-trans retinal to cell membrane preparations. The decrease in photoreceptor-mediated photophobic response at the stationary growth phase of cells is not due to photoreceptor degradation but due to a deficiency of the signal transduction chain in the cell.
Otomo
J
J
Max-Planck-Institut für Biochem e, Martinsried, Federal Republic of Germany.
Marwan
W
W
Oesterhelt
D
D
Desel
H
H
Uhl
R
R
D001426:Bacterial Proteins / Q000096:biosynthesis*; D001436:Bacteriorhodopsins / Q000502:physiology*; D002462:Cell Membrane / Q000502:physiology; D006217:Halobacterium / Q000502:physiology*; D008027:Light; D010786:Photoreceptor Cells / Q000502:physiology*; D012172:Retinaldehyde / Q000378:metabolism; D013057:Spectrum Analysis
D001426:Bacterial Proteins; D001436:Bacteriorhodopsins; D012172:Retinaldehyde