Recombination between VH pseudogenes.
The peculiar pattern of nucleotide differences between germline VH genes V104A/VAR104 and 122B could be the result of an exchange of genetic information through gene conversion. A palindromic sequence in one of the genes seems to have been the target site for the break that initiated recombination.
Blankenstein
T
T
Institut für Genetik, Universität zu Köln, F.R.G.
Rathbun
G A
GA
Tucker
P W
PW
Krawinkel
U
U
D000818:Animals; D001483:Base Sequence; D005785:Gene Conversion; D051379:Mice; D008815:Mice, Inbred Strains; D008969:Molecular Sequence Data; D011544:Pseudogenes; D011995:Recombination, Genetic