Localization of prolactin-like immunoreactivity in grafted human sweat glands.
Using a double-antibody immunoperoxidase technique, we demonstrated human prolactin-like material in some cells of the secretory coil and in luminal duct cells of sweat glands of human skin which had been carried as grafts on mice for 32-35 weeks. It therefore seems likely that a population of cells in the secretory coil synthesizes prolactin and can be considered as diffuse peripheral endocrine cells. The prolactin may function locally to regulate sweat electrolyte concentration.
Robertson
M T
MT
Department of Pediatrics, Georgetown University, Washington, DC 20007.
Alho
H R
HR
Martin
A A
AA
D000818:Animals; D004573:Electrolytes / Q000378:metabolism; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D051379:Mice; D011388:Prolactin / Q000276:immunology* / Q000378:metabolism; D013545:Sweat Glands / Q000276:immunology* / Q000378:metabolism / Q000637:transplantation; D014183:Transplantation, Heterologous
D004573:Electrolytes; D011388:Prolactin