Lupus-like syndrome in a mother and newborn following administration of hydralazine; a case report.
A very-low-birth-weight infant died from pericardial effusion and cardiac tamponade confirmed by the post-mortem findings. The mother suffered from lupus-like syndrome consequent to hydralazine treatment for pregnancy-induced hypertension. The possible relationship between mother-infant pathology and hydralazine administration is discussed.
Yemini
M
M
Department of Obstetrics and Gynecology, Kaplan Hospital, Rehovot, Israel.
Shoham
Z
Z
Dgani
R
R
Lancet
M
M
Mogilner
B M
BM
Nissim
F
F
Bar-Khayim
Y
Y
D000328:Adult; D005260:Female; D006801:Humans; D006830:Hydralazine / Q000009:adverse effects* / Q000627:therapeutic use; D006973:Hypertension / Q000188:drug therapy*; D007231:Infant, Newborn; D008177:Lupus Vulgaris / Q000139:chemically induced*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy*; D011297:Prenatal Exposure Delayed Effects; D013577:Syndrome
D006830:Hydralazine