title: Distribution of haptoglobin phenotypes in oesophageal and gastric cancer.
abstract: Haptoglobin (Hp) phenotypes were studied in 72 oesophageal and 104 gastric cancer patients and compared with 100 healthy controls to see if there is any association between oesophageal and gastric cancer and haptoglobin type. There was a significantly increased frequency of Hp 2-1 (59.7%) and Hp 2-2 (91.3%) in oesophageal and gastric cancer patients. Our results suggest that genetic factors play a role in the aetiology and pathogenesis of gastrointestinal tract malignancy.
authors.affiliation: Department of Gastroenterology, Osmania General Hospital, Hyderabad, India.
authors.forename: M
authors.initials: M
authors.lastname: Jayanthi
authors.forename: C M
authors.initials: CM
authors.lastname: Habibullah
authors.forename: M
authors.initials: M
authors.lastname: Ishaq
authors.forename: H
authors.initials: H
authors.lastname: Ali
authors.forename: P S
authors.initials: PS
authors.lastname: Babu
authors.forename: M M
authors.initials: MM
authors.lastname: Ali
mesh_terms: D004938:Esophageal Neoplasms / Q000235:genetics*; D005787:Gene Frequency; D006242:Haptoglobins / Q000235:genetics*; D006801:Humans; D010641:Phenotype; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000235:genetics*
chemical_list: D006242:Haptoglobins