title: [Effect of tourniquet occlusion on peripheral blood pooling and ventricular function].
abstract: Rotating tourniquets are traditionally part of the treatment of acute pulmonary edema. However, their effectiveness has been questioned. A radioisotope technique was therefore used to evaluate directly the increments in the blood volume of the leg after venous occlusion using a pressure of 60 mmHg in 26 patients with left ventricular (LV) dysfunction following myocardial infarction. The increment in mean radionuclide count at serial 15-second intervals (reflecting the blood volume in the leg distal to the occlusion) increased significantly from the pre-occlusion value by 46 +/- 26% (p less than 0.0005). Thus satisfactory trapping of blood is achieved even in LV failure. However, mean ejection fraction decreased slightly but significantly from 0.23 +/- 0.10 to 0.21 +/- 0.10 (p less than 0.05), a decrease observed in 18 of the 26 patients. LV end-diastolic and end-systolic volume equivalents tended to decrease slightly, but not in all patients. Mean stroke volume and cardiac output equivalents were reduced by 14% (p less than 0.0005), while calculated peripheral resistance increased significantly. The present study fails to support the hypothesis that preload reduction by tourniquets improves LV function.
authors.forename: H O
authors.initials: HO
authors.lastname: Klein
authors.forename: E
authors.initials: E
authors.lastname: Brodsky
authors.forename: R
authors.initials: R
authors.lastname: Ninio
authors.forename: A
authors.initials: A
authors.lastname: Bakst
authors.forename: E
authors.initials: E
authors.lastname: Di Segni
authors.forename: V
authors.initials: V
authors.lastname: Oren
authors.forename: B
authors.initials: B
authors.lastname: Beker
authors.forename: E
authors.initials: E
authors.lastname: Kaplinsky
mesh_terms: D001810:Blood Volume; D006321:Heart / Q000503:physiopathology*; D006352:Heart Ventricles / Q000503:physiopathology; D006439:Hemodynamics; D006801:Humans; D007866:Leg / Q000098:blood supply; D009203:Myocardial Infarction / Q000150:complications / Q000503:physiopathology*; D011654:Pulmonary Edema / Q000209:etiology / Q000628:therapy; D014111:Tourniquets