title: Plasmodium-specific immunoglobulin E in sera from an area of holoendemic malaria.
abstract: Serum samples obtained from adults living in an area of holoendemic malaria in Papua New Guinea and from control residents of Hawaii were tested for Plasmodium-specific immunoglobulin (Ig) E antibody by the enzyme-linked immunosorbent assay. Fifteen (33.3%) of the New Guinea sera had absorbance values indicative of seropositivity. Only half of the IgE-positive sera were concomitantly positive for antimalarial IgG antibody. All of the control sera were negative for antibody of both immunoglobulin classes.
authors.affiliation: Department of Tropical Medicine and Medical Microbiology, John A. Burns School of Medicine, University of Hawaii, Honolulu 96816.
authors.forename: R S
authors.initials: RS
authors.lastname: Desowitz
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis*; D000918:Antibody Specificity; D004797:Enzyme-Linked Immunosorbent Assay; D006254:Hawaii; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis; D008288:Malaria / Q000276:immunology*; D010219:Papua New Guinea; D010963:Plasmodium falciparum / Q000276:immunology*; D010965:Plasmodium malariae / Q000276:immunology*
chemical_list: D000913:Antibodies, Protozoan; D007074:Immunoglobulin G; D007073:Immunoglobulin E