title: Binding of inositol hexakisphosphate to the oxygenated derivative of dromedary (Camelus dromedarius) and human hemoglobin: 31P-NMR study.
abstract: Binding of inositol hexakisphosphate (IHP) to the oxygenated derivative of dromedary (Camelus dromedarius) and human hemoglobin (Hb) was investigated by 31P-NMR. The results obtained show that dromedary Hb binds, with different affinity, two IHP molecules per tetramer at distinct sites, while human Hb binds only one IHP molecule per tetramer.
authors.affiliation: Dipartimento di Scienze Biochimiche, Università di Roma La Sapienza, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Ascenzi
authors.forename: G
authors.initials: G
authors.lastname: Amiconi
authors.forename: E
authors.initials: E
authors.lastname: Rossi
authors.forename: A L
authors.initials: AL
authors.lastname: Segre
mesh_terms: D000818:Animals; D002162:Camelus / Q000097:blood*; D006801:Humans; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D010108:Oxyhemoglobins / Q000378:metabolism*; D010758:Phosphorus; D010833:Phytic Acid / Q000097:blood*; D011485:Protein Binding; D013045:Species Specificity
chemical_list: D010108:Oxyhemoglobins; D010758:Phosphorus; D010833:Phytic Acid