Acute and chronic pericholangiolitis in association with multifocal hepatic lymphangiomatosis.
Multifocal, lymphangiomatous lesions were found in the right lobe of the liver of a 9-year-old girl who died seven days after head trauma. We believe the lesions represent a cystic and pseudoneoplastic dilatation of liver lymphatics secondary to a posttraumatic complication, acute and chronic inflammation primarily of small bile ducts, and canaliculi (pericholangiolitis). The findings provide new evidence that inflammation and fluid overload, in the absence of a congenital malformation, are cardinal factors in the pathogenesis of some forms of lymphangiomatosis.
Sathyavagiswaran
L
L
Office of the Chief Medical Examiner-Coroner, Los Angeles County, CA.
Sherwin
R P
RP
D001648:Bile Canaliculi / Q000473:pathology*; D001653:Bile Ducts, Intrahepatic / Q000473:pathology*; D002648:Child; D002761:Cholangitis / Q000209:etiology* / Q000473:pathology; D006259:Craniocerebral Trauma / Q000150:complications*; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000209:etiology*; D008202:Lymphangioma / Q000209:etiology*