The dissolution of urinary mucus after cystoplasty.
Three agents have been tested for mucolytic activity to prevent or treat difficulties in bladder emptying following augmentation and substitution cystoplasty, particularly in patients emptying by intermittent self-catheterisation. Carbocysteine produced precipitation of mucus, which was found not to be helpful. N-acetylcysteine and urea both dissolved mucus, but urea proved to be more effective.
Gillon
G
G
Department of Surgery and Urology, Guy's Hospital, London.
Mundy
A R
AR
D000111:Acetylcysteine / Q000627:therapeutic use; D002233:Carbocysteine / Q000627:therapeutic use; D005100:Expectorants / Q000627:therapeutic use*; D006801:Humans; D066298:In Vitro Techniques; D009093:Mucus / Q000187:drug effects*; D011183:Postoperative Complications / Q000188:drug therapy*; D014508:Urea / Q000627:therapeutic use; D001743:Urinary Bladder / Q000601:surgery*; D014556:Urine / Q000032:analysis*
D005100:Expectorants; D002233:Carbocysteine; D014508:Urea; D000111:Acetylcysteine