title: Elevated serum CK-BB levels in patients with cerebral transtentorial herniation after ischemic stroke.
abstract: We examined the time course of CK and its isoenzymes in 15 patients with severe ischemic stroke. Patients with cerebral transtentorial herniation (n = 7) had the highest CK-BB activity during herniation (1.54 +/- 0.6 U/L, mean +/- SD; range: 1.0-2.6 U/L). These values were distinctly above the values of a control group of 20 patients with non-neurological diseases (0.39 +/- 0.2 U/L, mean +/- SD). In patients with smaller lesions without herniation (n = 8) the maximum CK-BB increase was lower (0.56 +/- 0.26 U/L, mean +/- SD).
authors.affiliation: Klinisch-chemisches Zentrallabor der Medizinischen Universitätsklinik, Homburg/Saar, FRG.
authors.forename: M
authors.initials: M
authors.lastname: Corea
authors.forename: R
authors.initials: R
authors.lastname: Kloss
authors.forename: T
authors.initials: T
authors.lastname: Stober
authors.forename: K
authors.initials: K
authors.lastname: Schimrigk
authors.forename: H E
authors.initials: HE
authors.lastname: Keller
mesh_terms: D000368:Aged; D002526:Cerebellar Diseases / Q000201:enzymology* / Q000209:etiology; D002561:Cerebrovascular Disorders / Q000150:complications*; D003402:Creatine Kinase / Q000097:blood*; D004677:Encephalocele / Q000201:enzymology* / Q000209:etiology; D005260:Female; D006801:Humans; D007527:Isoenzymes; D008297:Male; D008875:Middle Aged
chemical_list: D007527:Isoenzymes; D003402:Creatine Kinase