Hutchinson-Gilford progeria syndrome: report of a Libyan family and evidence of autosomal recessive inheritance.
A Libyan family with the Hutchinson-Gilford progeria syndrome affecting three children of two sisters is described. The proband was ascertained because of repeated unhealing fractures. The pattern of inheritance appeared autosomal recessive.
Khalifa
M M
MM
Department of Pediatrics, Queen's University, Kingston, Ontario, Canada.
D002675:Child, Preschool; D003241:Consanguinity; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D008002:Libya; D008297:Male; D010014:Osteolysis / Q000000981:diagnostic imaging / Q000235:genetics; D010375:Pedigree; D011371:Progeria / Q000000981:diagnostic imaging / Q000235:genetics*; D011859:Radiography