title: [Hemodynamic and pulmonary effects of nifedipine].
abstract: The authors reviewed the actions of nifedipine, a blocker of calcium channels, on the systemic and pulmonary circulation. The mechanism of action of the drug on the systemic and pulmonary circulation and on the gas exchange is discussed. The main effects of nifedipine on the coronary circulation and indications for therapeutic use of the drug are discussed on the topics of coronary insufficiency, systemic and pulmonary blood hypertension, acute respiratory failure, and Raynaud's phenomenon.
authors.forename: D
authors.initials: D
authors.lastname: Feder
authors.forename: H
authors.initials: H
authors.lastname: Romaldini
authors.forename: M L
authors.initials: ML
authors.lastname: dos Santos
mesh_terms: D000818:Animals; D002118:Calcium / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D004285:Dogs; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D009131:Muscle, Smooth, Vascular / Q000187:drug effects; D009543:Nifedipine / Q000494:pharmacology*; D011652:Pulmonary Circulation / Q000187:drug effects*; D014655:Vascular Resistance / Q000187:drug effects
chemical_list: D009543:Nifedipine; D002118:Calcium
vernacular_title: Efeito hemodinâmico sistêmico e pulmonar da nifedipina.