Hepatotoxicity and inhalation anesthetics: views in the era of isoflurane.
The halogenated inhalation anesthetics continue to be an important group of drugs in current anesthesia practice. The purpose of this article is to discuss current concepts of the mechanisms of halothane-induced hepatotoxicity and to attempt to answer the question: Do all halogenated inhalation anesthetics share halothane's propensity to hepatotoxicity?
Brown
B R
BR
Department of Anesthesiology, University of Arizona College of Medicine, Arizona Health Sciences Center, Tucson 85724.
D000769:Anesthesia, Inhalation; D000818:Animals; D006221:Halothane / Q000633:toxicity*; D006801:Humans; D007530:Isoflurane / Q000633:toxicity*; D008099:Liver / Q000187:drug effects*
D007530:Isoflurane; D006221:Halothane