[Postoperative analgesia and dexamethasone].
A randomized, double-blind, prospective study was carried out in 100 patients who had undergone some type of surgical treatment in order to evaluate the degree of pain and relief of pain, the degree of achieved analgesia according to the opinion of the observer and consumption of analgesic agents. The evaluation was carried out on seven occasions during the first 12 hours of the postoperative period. Patients received dexamethasone (4 mg before or after the operation or 8 mg after the operation), 6-methylprednisolone (16 mg at the end of the operation) or nothing (control group). Regardless of type, dose or timing of administration of the drugs, all patients receiving corticosteroids presented less pain, more relief of pain (expressed by themselves or in opinion of the observer) and needed lower doses of analgesics during the studied time.
Miralles
F S
FS
Cárceles
M D
MD
Micol
J A
JA
Hernández
J
J
del Pino
A
A
D000293:Adolescent; D000328:Adult; D000632:Aminopyrine / Q000031:analogs & derivatives*; D003907:Dexamethasone / Q000627:therapeutic use*; D004177:Dipyrone / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use*; D008875:Middle Aged; D010149:Postoperative Pain / Q000188:drug therapy*; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic
D000632:Aminopyrine; D004177:Dipyrone; D003907:Dexamethasone; D008775:Methylprednisolone
Analgesia postoperatoria y dexametasona.