title: Use of botulinum toxin to treat blepharospasm in a 16-year-old with a dystonic syndrome.
abstract: A 16-year-old boy with generalized dystonia had continuous, severe blepharospasm and facial grimacing. Local intradermal injections of botulinum A toxin greatly reduced the spasms and improved function. No side effects were observed. Local botulinum A toxin injections may be useful in the treatment of eyelid and facial spasms in patients with generalized dystonias.
authors.affiliation: Department of Ophthalmology, University of California School of Medicine, San Francisco.
authors.forename: S R
authors.initials: SR
authors.lastname: Seiff
authors.forename: L N
authors.initials: LN
authors.lastname: Freeman
authors.forename: D L
authors.initials: DL
authors.lastname: Bluestone
authors.forename: B O
authors.initials: BO
authors.lastname: Berg
mesh_terms: D000293:Adolescent; D001764:Blepharospasm / Q000188:drug therapy* / Q000209:etiology; D001905:Botulinum Toxins / Q000008:administration & dosage / Q000627:therapeutic use*; D004421:Dystonia / Q000150:complications; D005141:Eyelid Diseases / Q000188:drug therapy*; D006801:Humans; D007271:Injections, Intradermal; D008297:Male
chemical_list: D001905:Botulinum Toxins