[Detection of a mitogenic serum factor in psoriasis].
Using human fibroblast cultures in vitro, a study was carried out on the effect of sera from patients with psoriasis and from healthy volunteers on DNA and protein synthesis. Thymidine incorporation was enhanced under the influence of psoriatic sera whereas there was no difference in amino acid incorporation in the control sera. Based on these results, we conclude that systemic psoriasis may be under humoral control.
Holzmann
H
H
Zentrum der Dermatologie und Venerologie, Johann Wolfgang Goethe-Universität Frankfurt.
Bernd
A
A
Hohlmaier
K
K
D000328:Adult; D002455:Cell Division; D002478:Cells, Cultured; D004261:DNA Replication; D005260:Female; D005347:Fibroblasts / Q000166:cytology; D006801:Humans; D008297:Male; D008934:Mitogens / Q000097:blood*; D011565:Psoriasis / Q000097:blood*
D008934:Mitogens
Zur Kenntnis eines mitogenen Serumfaktors bei Psoriasis.