[A new cell line of rat gasserian ganglion neurinoma NGUK-1].
A new cell line has been derived from the rat gasserian ganglion neurinoma NGUK-1 induced by transplacental administration of ethylnitrosourea. It is characterized by an astrocyte-like growth pattern at the low cell density, and by an epitheliocyte-like pattern in the confluent monolayer. The cell line displays a high proliferative activity, its maximum mitotic index and proliferative pool being--2.5 and 96%, respectively. The chromosome number ranges between 20 to 100. The chromosome modal number is 39--44. The new cell line has been used for the express diagnostic of rabies, for determination of serum glial toxicity in neurologic patients, and interferon titration.
Avtsyn
A P
AP
Kondakova
L I
LI
Khalanskiĭ
A S
AS
Poliakova
G P
GP
Chudinovskaia
N V
NV
D000818:Animals; D001345:Autoradiography; D002460:Cell Line; D002875:Chromosomes / Q000648:ultrastructure; D005038:Ethylnitrosourea; D005726:Ganglia, Parasympathetic; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D008938:Mitosis; D009368:Neoplasm Transplantation; D009442:Neurilemmoma / Q000139:chemically induced / Q000648:ultrastructure*; D051381:Rats; D014407:Tumor Cells, Cultured
D005038:Ethylnitrosourea
Novaia kletochnaia liniia nevrinomy gasserova uzla krysy NGUK-1.