title: [Antigen recognition and signal transduction in T lymphocytes].
abstract: Stopped-flow fluorometry gave a unique opportunity to observe a direct cellular interaction between functionally different subsets of lymphocytes in vitro. By this method the molecular mechanism of receptor-mediated recognition and signaling in T lymphocytes (T cells) has been well analyzed. The method is further in progress to observe calcium signals in a single T lymphocyte by using a digital imaging fluorescence microscope.
authors.forename: M
authors.initials: M
authors.lastname: Nakanishi
mesh_terms: D000818:Animals; D000941:Antigens / Q000276:immunology*; D002118:Calcium / Q000378:metabolism / Q000502:physiology; D005470:Fluorometry; D008213:Lymphocyte Activation; D008285:Major Histocompatibility Complex / Q000276:immunology; D015290:Second Messenger Systems; D015398:Signal Transduction; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D000941:Antigens; D002118:Calcium