[Step-wise expression of melanoma-associated antigens in tumor progression].
Selection of monoclonal antibodies for differential reactivity with benign and malignant melanocytic lesions has led to the identification of molecules which may be involved in the development of metastases. Based on the observed alterations in the antigenic profile we propose a scheme representing the tumor progression of melanocytes to metastatic melanoma.
Lehmann
J M
JM
Institut für Immunologie, Universität München.
Holzmann
B
B
Rothbächer
U
U
Riethmüller
G
G
Johnson
J P
JP
D000951:Antigens, Neoplasm; D006801:Humans; D008545:Melanoma / Q000473:pathology*; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins / Q000032:analysis*; D009367:Neoplasm Staging; D009508:Nevus, Pigmented / Q000473:pathology*; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*
D000951:Antigens, Neoplasm; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins
Schrittweise Expression von Melanom-assoziierten Antigenen während der Tumorprogression.