title: [Possible approaches to creating phospholipid preparations--acceptors of membrane cholesterol].
abstract: The capability of liposomes with plant phosphatidylcholine to extract cholesterol from erythrocyte membrane was investigated. It was shown, that plant phosphatidylcholine extracted 42% of membrane cholesterol, without causing haemolysis. This cholesterol extraction was responsible for the decrease of membrane microviscosity and for the increase of Na+, K+-ATPase activity. It is suggested that it is possible to create the extractive agent of cholesterol with plant phosphatidylcholine.
authors.forename: E M
authors.initials: EM
authors.lastname: Khalilov
authors.forename: T I
authors.initials: TI
authors.lastname: Torkhovskaia
authors.forename: E S
authors.initials: ES
authors.lastname: Fortinskaia
authors.forename: A M
authors.initials: AM
authors.lastname: Kaliman
authors.forename: M M
authors.initials: MM
authors.lastname: Kochetova
mesh_terms: D000818:Animals; D000924:Anticholesteremic Agents / Q000494:pharmacology*; D002784:Cholesterol / Q000097:blood / Q000302:isolation & purification*; D004337:Drug Carriers; D015195:Drug Design; D004355:Drug Stability; D004655:Emulsions; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000378:metabolism; D008081:Liposomes; D008563:Membrane Lipids / Q000097:blood / Q000302:isolation & purification*; D010713:Phosphatidylcholines / Q000494:pharmacology*; D011817:Rabbits
chemical_list: D000924:Anticholesteremic Agents; D004337:Drug Carriers; D004655:Emulsions; D008081:Liposomes; D008563:Membrane Lipids; D010713:Phosphatidylcholines; D002784:Cholesterol
vernacular_title: Vozmozhnye podkhody k sozdaniiu fosfolipidnykh preparatov--aktseptorov membrannogo kholesterina.