[Experimental study of hemodynamic changes following obliteration of the vertebral artery and surgical treatment].
This experiment on dogs was to compare the hemodynamic changes following ligation of the carotid artery on one side and the first segment of vertebral artery on both sides, with that after restoration of the cut-off circulation through anastomosing the previously ligated carotid and vertebral arteries. The hemodynamic changes after obliteration and following restoration of circulation, both in vessels and cerebellum, were monitored by ways of regional clearance of hydrogen, Doppler velocimetory of blood flow, angiography of vertebral artery and blood gas analysis. The difference of results in each paired sample was statistically very significant. These models worked with success in 20 out of 24 dogs, a rate of 83%. Following re-establishment of circulation by means of vascular anastomosis, blood flow and blood supply to the ischemic cerebellum increased to normal or nearly normal. It suggests that this kind of surgical procedure may be of value in clinical treatment.
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D000818:Animals; D001157:Arterial Occlusive Diseases / Q000503:physiopathology* / Q000601:surgery; D001783:Blood Flow Velocity; D002531:Cerebellum / Q000098:blood supply; D002560:Cerebrovascular Circulation; D004285:Dogs; D005260:Female; D006439:Hemodynamics; D008297:Male; D014463:Ultrasonography; D014711:Vertebral Artery / Q000601:surgery*