title: [Comparative effects of desiccated thyroid gland and sodium salt of L-thyroxine in the treatment of hypothyroidism].
abstract: The studies comparing the actions of dried thyroid gland (Thyroideum-Polfa) with L-thyroxine sodium (L-T4) were carried out in 20 female patients with hypothyroidism, including 19 patients with the primary hypothyroidism and 1 patient with hypothyroidism secondary to pituitary deficiency. Administration of the dried thyroid gland did not normalize blood serum T4 an TSH in any patient. Normal serum T4 or even slightly increased was achieved in all patients treated with L-T4. Serum TSH was normalized in 17 patients with the primary hypothyroidism. The following conclusions have been drawn: 1. Dried thyroid gland (Thyroideum-Polfa) is ineffective in the treatment of hypothyroidism. 2. Serum TSH remains elevated despite normal serum T3 in cases of the primary hypothyroidism with decreased serum T4 levels. 3. Sodium salt of L-thyroxine should be used for the treatment of hypothyroidism. 1-Triiodothyronine sodium may be used as an adjuvant therapy.
authors.forename: T
authors.initials: T
authors.lastname: Górowski
authors.forename: J
authors.initials: J
authors.lastname: Puciłowska
authors.forename: K
authors.initials: K
authors.lastname: Wernic
mesh_terms: D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D005260:Female; D006728:Hormones / Q000627:therapeutic use; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000188:drug therapy*; D008875:Middle Aged; D013962:Thyroid (USP) / Q000627:therapeutic use*; D013963:Thyroid Hormones / Q000627:therapeutic use*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood / Q000627:therapeutic use*; D014284:Triiodothyronine / Q000097:blood
chemical_list: D006728:Hormones; D013962:Thyroid (USP); D013963:Thyroid Hormones; D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine
vernacular_title: Porównanie działania preparatu suszonej tarczycy z działaniem soli sodowej L-tyroksyny w leczeniu niedoczynności tarczycy.