Methylation of replicating and nonreplicating DNA in the ciliate Tetrahymena thermophila.
Methylation of adenine in replicating and nonreplicating DNA of the ciliate Tetrahymena thermophila was examined. In growing cells, 87% of the methylation occurred on the newly replicated daughter strand, but methylation was also detectable on the parental strand. Methylation of nonreplicating DNA from starved cells was demonstrated.
Harrison
G S
GS
Brandeis University, Department of Biology, Waltham, Massachusetts 02254.
Karrer
K M
KM
D000225:Adenine / Q000031:analogs & derivatives / Q000378:metabolism; D000818:Animals; D004247:DNA / Q000378:metabolism*; D004261:DNA Replication; D008745:Methylation; D013768:Tetrahymena / Q000254:growth & development / Q000378:metabolism*
D000225:Adenine; D004247:DNA; C000730567:6-methyladenine