title: tRNA-rRNA sequence matches from inter- and intraspecies comparisons suggest common origins for the two RNAs.
abstract: 1. Comparisons were made of the results of searches within and among different species of organisms for sequence matches between transfer RNAs and ribosomal RNAs. The purpose was to determine whether the matching sequences might result from selection acting on the two RNAs within a common cellular environment. 2. The results indicate that most matches do not reflect such selection. The matches described were more frequent than those found in searches among randomized sequences and the frequency of intraspecific matches was not significantly higher than that of interspecific matches. 3. The matches are thought to identify conserved vestiges of a molecule or molecules ancestral to both classes of RNAs (Bloch, D.P., McArthur, B. and Mirrop, S. (1985). BioSystems, 17: 209-225). The matching sequences are interpreted as homologies.
authors.affiliation: Botany Department, University of Texas, Austin 78712.
authors.forename: D P
authors.initials: DP
authors.lastname: Bloch
authors.forename: B
authors.initials: B
authors.lastname: McArthur
authors.forename: R C
authors.initials: RC
authors.lastname: Guimarães
authors.forename: J
authors.initials: J
authors.lastname: Smith
authors.forename: M P
authors.initials: MP
authors.lastname: Staves
mesh_terms: D000926:Anticodon / Q000235:genetics; D001483:Base Sequence; D004926:Escherichia coli / Q000235:genetics*; D005815:Genetic Code; D006217:Halobacterium / Q000235:genetics; D008928:Mitochondria / Q000032:analysis; D011336:Probability; D012335:RNA, Ribosomal / Q000235:genetics*; D012343:RNA, Transfer / Q000235:genetics*; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid
chemical_list: D000926:Anticodon; D012335:RNA, Ribosomal; D012343:RNA, Transfer