title: [Pericentric inversion of the human Y chromosome].
abstract: Pericentric inversion of the human Y chromosome has an estimated frequency of the one per thousand. This inversion is always inherited but also is possible a de novo presentation. Sometimes this inverted chromosome is associated with the Down, Klinefelter and other chromosomal syndromes. For the carriers of pericentric inversion the risk of the mental retardation or multiple abortion is not apparently increase and there is not relation with abnormal phenotypic features. For some authors the pericentric inversion of the human Y chromosome is only a rare chromosomal heteromorphism.
authors.affiliation: Departamento de Genética Humana, Hospital Clínico de San Cecilio, Granada.
authors.forename: M A
authors.initials: MA
authors.lastname: Motos Guirao
mesh_terms: D000293:Adolescent; D000328:Adult; D002869:Chromosome Aberrations; D007446:Chromosome Inversion; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D007248:Infertility, Male / Q000235:genetics; D008607:Intellectual Disability / Q000235:genetics; D008297:Male; D011296:Prenatal Diagnosis; D014998:Y Chromosome
vernacular_title: Inversiones pericéntricas del cromosoma Y humano.