title: Mortality versus improvement in severe chronic asthma: physiologic and psychologic factors.
abstract: Improved outcome (1 to 10 years) of 140 asthmatic children retrospectively correlated with 8 of 49 variables in admission evaluation: (1) age of onset, (2) IgE, (3) night/early AM bronchospasm, (4) aggression, (5) severely disrupted family circumstances, (6) severe psychopathology, (7) psychotic signs, and (8) I.Q. Patients with fatal outcome (6% to 12%) deviated in the last three variables; most were 12.1 to 16.5 years, male, Black/Hispanic, aggressive, depressed and/or anxious. Clinical implications include high-risk identification on the basis of psychologic and physiologic variables, preventative measures, and consideration of residential treatment.
authors.affiliation: Blythedale Children's Hospital, Valhalla, New York.
authors.forename: A
authors.initials: A
authors.lastname: Mascia
authors.forename: S
authors.initials: S
authors.lastname: Frank
authors.forename: A
authors.initials: A
authors.lastname: Berkman
authors.forename: L
authors.initials: L
authors.lastname: Stern
authors.forename: L
authors.initials: L
authors.lastname: Lampl
authors.forename: M
authors.initials: M
authors.lastname: Davies
authors.forename: T
authors.initials: T
authors.lastname: Yeager
authors.forename: B
authors.initials: B
authors.lastname: Birmaher
authors.forename: E
authors.initials: E
authors.lastname: Chieco
mesh_terms: D000223:Adaptation, Psychological; D000293:Adolescent; D000374:Aggression; D001007:Anxiety; D001249:Asthma / Q000401:mortality* / Q000503:physiopathology / Q000523:psychology; D002648:Child; D002908:Chronic Disease; D003863:Depression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D008297:Male
chemical_list: D007073:Immunoglobulin E