title: Case report of successful use of VP-16 in nasopharyngeal carcinoma.
abstract: We report the use of VP-16 as a single agent for the treatment of nasopharyngeal carcinoma. Our patient, a 16-year-old Black Haitian male, had complete clinical and radiographic response to VP-16. The remission continued for 14 months. The patient experienced minimal toxicity. We believe that the good response, excellent compliance, and minimal toxicity experienced by our patient should encourage more trials of VP-16 as upfront therapy for patients with nasopharyngeal carcinoma.
authors.affiliation: Department of Pediatrics, University of Miami/Jackson Memorial Hospital, Florida 33101.
authors.forename: D
authors.initials: D
authors.lastname: Daghistani
authors.forename: J
authors.initials: J
authors.lastname: Davis
authors.forename: S
authors.initials: S
authors.lastname: Toledano
mesh_terms: D000293:Adolescent; D002277:Carcinoma / Q000188:drug therapy*; D005047:Etoposide / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000188:drug therapy*; D010349:Patient Compliance; D012074:Remission Induction
chemical_list: D005047:Etoposide