[Clinical evaluation of doxofylline sachets in a pediatric population].
Therapeutic efficacy and tolerability of doxofylline 200 mg sachets, were evaluated, in a pediatric population in comparison with placebo. After double blind randomization, 11 patients aged from 6 to 12 years, were treated for 14 consecutive days. Doxofylline was administered at the daily dose of 12 mg/kg in two times. In the doxofylline group the authors observed a significative improvement of the evaluated spirometric paramethers (FEV1, FCV, FEF, FMF, PEF, MVV); in the placebo group there were only casual modifications. None of the patients treated complained of any side effect.
Bagnato
G
G
Fodale
P
P
Bottari
M
M
D000996:Antitussive Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D016032:Randomized Controlled Trials as Topic; D012129:Respiratory Function Tests; D012140:Respiratory Tract Diseases / Q000188:drug therapy* / Q000503:physiopathology; D013806:Theophylline / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use
D000996:Antitussive Agents; D013806:Theophylline; C029797:doxofylline
Valutazione clinica della doxofillina bustine per os in una popolazione in età pediatrica.