title: The effect of hemiplegia on bone mass and soft tissue body composition.
abstract: The content of bone mineral (BMC), lean tissue, and fat tissue were measured by single and dual photon absorptiometry in both the paretic and the non-paretic limbs of 15 patients, hemiplegic due to cerebrovascular accident 23-38 weeks earlier. Compared with the non-paretic arm, the paretic arm had approximately 10% lower (P less than 0.01) BMC. This difference was largest at the measuring site with the highest ratio of trabecular to compact bone. The paretic leg had a 4% (P less than 0.001) lower BMC than the non-paretic leg. For both the arms and the legs, the lean content was lower (P less than 0.05) and the fat content higher (P less than 0.01) in the paretic than in the non-paretic. This was relatively more pronounced in the arms than in the legs. We conclude that partial immobilization, owing to paresis after a cerebrovascular accident, results in characteristic changes in the affected limbs, with a marked decrease in the content of bone and lean tissue and a pronounced increase in fatty tissue.
authors.affiliation: Department of Medicine, Glostrup Hospital, Copenhagen, Denmark.
authors.forename: E
authors.initials: E
authors.lastname: Iversen
authors.forename: C
authors.initials: C
authors.lastname: Hassager
authors.forename: C
authors.initials: C
authors.lastname: Christiansen
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism*; D000328:Adult; D000368:Aged; D001132:Arm; D001823:Body Composition; D001842:Bone and Bones / Q000378:metabolism*; D006429:Hemiplegia / Q000378:metabolism*; D006801:Humans; D007866:Leg; D008875:Middle Aged; D009132:Muscles / Q000378:metabolism*