title: Serum urate level and cancer.
abstract: Histograms of the serum uric acid level of cancer patients (n = 501) and healthy controls (n = 15150) are compared. The statistical evaluation of the data yields significantly lower uric acid levels for cancer patients than for healthy persons (P less than 0.0001 for males, P less than 0.001 for females). These results support the theory that reactive species of oxygen (singlet oxygen and oxygen radicals) play an important role during carcinogenesis.
authors.affiliation: Ludwig Boltzmann Institut fuer klinische Onkologie, Vienna, Austria.
authors.forename: E
authors.initials: E
authors.lastname: Lickl
authors.forename: G
authors.initials: G
authors.lastname: Alth
authors.forename: R
authors.initials: R
authors.lastname: Ebermann
authors.forename: R H
authors.initials: RH
authors.lastname: Beck
authors.forename: K
authors.initials: K
authors.lastname: Tuma
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000097:blood* / Q000175:diagnosis; D014527:Uric Acid / Q000097:blood*
chemical_list: D014527:Uric Acid