Neurogenic mediators in control of pulpal blood flow.
In view of recent findings, classical nerve-released transmitters that modulate pulpal blood flow share their roles with novel vasoactive peptides. Noradrenaline coexists with neuropeptide Y in sympathetic nerves in the pulp and both substances contribute to a vasoconstriction. Vasoactive intestinal peptide has vasodilator effects and its presence in nerves in the pulp may represent a parasympathetic influence on pulpal vessels. Sensory nerves in the pulp contain a number of peptides which have vasodilatory effects. They are released and cause rapid increase in blood flow when the tooth is reached by an intense stimulus. A population of sensory nerves may thus play a role in instant defense reactions in the pulp.
Olgart
L M
LM
Edwall
B
B
Gazelius
B
B
D003782:Dental Pulp / Q000098:blood supply* / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D014662:Vasoconstrictor Agents
D014662:Vasoconstrictor Agents