Influence of some carbohydrates and concanavalin A on the adherence of Candida albicans in vitro to buccal epithelial cells.
The influence of some carbohydrates and of a lectin, Concanavalin A on the in vitro adherence of ten C. albicans strains to buccal epithelial cells has been assessed. D-glucose, D-galactose and sucrose significantly (p less than 0.005) enhanced the adherence and so did D-mannose (p less than 0.025). Incubation with D-xylose, D-ribose, D-fructose, maltose, lactose and raffinose did not influence adherence. Pretreatment of the fungal cells or epithelial cells with glucose and mannose did not enhance adherence. Concanavalin A significantly inhibited the adherence of fungal cells to buccal epithelial cells both when it was added to the test medium (p less than 0.005) and when the fungal or epithelial cells were pretreated with it (p less than 0.001).
Macura
A B
AB
Institute of Microbiology, Medical Academy, Cracow, Poland.
Tondyra
E
E
D002176:Candida albicans / Q000187:drug effects / Q000502:physiology*; D002241:Carbohydrates / Q000494:pharmacology*; D002448:Cell Adhesion / Q000187:drug effects; D002478:Cells, Cultured; D003208:Concanavalin A / Q000494:pharmacology*; D006801:Humans; D009061:Mouth Mucosa / Q000166:cytology / Q000382:microbiology*
D002241:Carbohydrates; D003208:Concanavalin A