title: [Keratoacanthoma centrifugum marginatum].
abstract: Keratoacanthoma centrifugum marginatum (KCM) is a rare distinct variant of keratoacanthoma. Based on three personal observations and a review of the literature, the authors describe the clinical and histological features of this neoplasm. Clinically KCM is characterized by the lack of a tendency for spontaneous remission and by continuous centrifugal spread. Histologically there is a subclinical, iceberg-like growth pattern. Like keratoacanthoma, KCM is a highly differentiated, biologically benign, non-metastasizing tumour. The treatment of choice is early excision of the tumour.
authors.affiliation: Dermatologische Klinik und Poliklinik, Julius-Maximilians-Universität Würzburg.
authors.forename: H
authors.initials: H
authors.lastname: Hackel
authors.forename: G
authors.initials: G
authors.lastname: Burg
authors.forename: W
authors.initials: W
authors.lastname: Lechner
authors.forename: W
authors.initials: W
authors.lastname: Stolz
authors.forename: J
authors.initials: J
authors.lastname: Ring
authors.forename: O
authors.initials: O
authors.lastname: Braun-Falco
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D005260:Female; D006801:Humans; D007636:Keratoacanthoma / Q000175:diagnosis* / Q000473:pathology; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000175:diagnosis* / Q000473:pathology
vernacular_title: Keratoacanthoma centrifugum marginatum.