[Effect of isosorbide dinitrate on neutrophil migration in vivo].
The influence of isosorbide dinitrate on polymorphonuclear neutrophils migration into a sterile inflammatory focus was evaluated in 12 patients with ischemic heart disease. The number of neutrophils migrated into the "skin window" increased significantly during treatment with isosorbide. Also granulocyte clearance increased in comparison with control investigation. Possible clinical implications of this phenomenon are discussed.
Wysocki
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H
Siminiak
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Szczepanik
A
A
D000328:Adult; D002634:Chemotaxis, Leukocyte / Q000187:drug effects* / Q000276:immunology; D003327:Coronary Disease / Q000188:drug therapy* / Q000276:immunology; D005260:Female; D006801:Humans; D007548:Isosorbide Dinitrate / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000187:drug effects / Q000276:immunology*; D012884:Skin Window Technique
D007548:Isosorbide Dinitrate
Wpływ dwuazotanu izosorbidu na migracje granulocytów obojetnochłonnych in vivo.