[An experimental study of the enzyme systems of the initial and final stages of nutrient hydrolysis in the small intestine upon an early transition to qualitatively different rations].
It is shown that when small rats are early (beginning with the 18th day of life) given semisynthetic diets the reactions of the pancreatic and intestinal enzyme systems become nonspecific, and they are expressed in a rise of both proteolytic and carbohydrase activities, regardless of the content of proteins or carbohydrates in the diet. This reaction is of stress nature, and the hypothalamo-hypophysial-medullar system participates in its realization. During further maintenance of the small rats on special diets (30 days) it is recorded that the enzyme spectrum corresponds to the diet composition: when the protein diet is used proteolytic enzyme activity prevails, while in case of carbohydrate diets enzyme activities of pancreatic and enteral carbohydrases predominate. A conclusion has been made that under conditions of early semisynthetic feeding the adaptation of the digestive system to the food content is first realized through the mechanisms of hormonal regulation, and then--the substrate one.
Demidova
A I
AI
Kotova
L M
LM
Rakhimov
K R
KR
Smirnova
G I
GI
D000818:Animals; D004032:Diet; D004798:Enzymes / Q000378:metabolism*; D005526:Food, Formulated; D006868:Hydrolysis; D007421:Intestine, Small / Q000201:enzymology*; D010179:Pancreas / Q000201:enzymology; D051381:Rats; D011919:Rats, Inbred Strains
D004798:Enzymes
Izuchenie v éksperimente fermentnykh sistem nachal'nogo i zakliuchitel'nogo étapov gidroliza pitatel'nykh veshchestv v tonkoĭ kishke pri prezhdevremennom perevode na kachestvenno razlichnye ratsiony.