title: [Lung histopathology during plutonium-238 incorporation].
abstract: In experiments with albino mongrel female rats a study was made of the response of the lungs to a single intratracheal injection of nitrate of 238Pu (0.4-740 kBq/kg). The nature of the inflammatory disease, the lymphoid tissue condition, pneumosclerosis occurrence, and the frequency and spectrum of lung tumors were shown to be a function of dose of the radionuclide administered.
authors.forename: E S
authors.initials: ES
authors.lastname: Zhorova
authors.forename: G A
authors.initials: GA
authors.lastname: Zalikin
authors.forename: P G
authors.initials: PG
authors.lastname: Nisimov
mesh_terms: D000818:Animals; D004307:Dose-Response Relationship, Radiation; D005260:Female; D008168:Lung / Q000378:metabolism / Q000473:pathology / Q000528:radiation effects*; D008169:Lung Abscess / Q000209:etiology / Q000378:metabolism / Q000473:pathology; D008175:Lung Neoplasms / Q000209:etiology / Q000378:metabolism / Q000473:pathology; D009381:Neoplasms, Radiation-Induced / Q000209:etiology / Q000378:metabolism / Q000473:pathology; D009566:Nitrates; D011005:Plutonium / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics*; D011658:Pulmonary Fibrosis / Q000209:etiology / Q000378:metabolism / Q000473:pathology; D051381:Rats; D012598:Sclerosis; D013997:Time Factors
chemical_list: D009566:Nitrates; C015459:plutonium nitrate; D011005:Plutonium
vernacular_title: Gistopatologiia legkikh pri inkorporatsii plutoniia-238.