Mortality versus improvement in severe chronic asthma: physiologic and psychologic factors.
Improved outcome (1 to 10 years) of 140 asthmatic children retrospectively correlated with 8 of 49 variables in admission evaluation: (1) age of onset, (2) IgE, (3) night/early AM bronchospasm, (4) aggression, (5) severely disrupted family circumstances, (6) severe psychopathology, (7) psychotic signs, and (8) I.Q. Patients with fatal outcome (6% to 12%) deviated in the last three variables; most were 12.1 to 16.5 years, male, Black/Hispanic, aggressive, depressed and/or anxious. Clinical implications include high-risk identification on the basis of psychologic and physiologic variables, preventative measures, and consideration of residential treatment.
Mascia
A
A
Blythedale Children's Hospital, Valhalla, New York.
Frank
S
S
Berkman
A
A
Stern
L
L
Lampl
L
L
Davies
M
M
Yeager
T
T
Birmaher
B
B
Chieco
E
E
D000223:Adaptation, Psychological; D000293:Adolescent; D000374:Aggression; D001007:Anxiety; D001249:Asthma / Q000401:mortality* / Q000503:physiopathology / Q000523:psychology; D002648:Child; D002908:Chronic Disease; D003863:Depression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D008297:Male
D007073:Immunoglobulin E