[Sudden deafness: apropos of 19 cases. Results of treatment with pentoxifylline. Value of erythrocyte filtration time].
Between March 85 and November 86, 20 patients underwent treatment for sudden deafness [19] or bilateral tinnitus [1] by Pentoxifylline (1 200 mg/24 Hrs, including 400 mg IV over 24 Hrs) and Carbogen sessions (2 or 3/24 Hrs), during six days on an in-patient basis, followed by 1 200 mg/24 Hrs orally during another eight days. The results, assessed by clinical examination, audiometry, and erythrocyte filtration time (using the Reid and Dormandy method) on the first, sixth, and fourtheenth days, were: -- good or very good a little more than 75%, -- moderate: 5%, -- poor: a little fewer than 20%. Filtration times in a group of asymptomatic patients, determined by the same method, were used as a reference.
Denis
F
F
CHI de Poissy.
Ketari
M
M
Benzaken
J
J
Renou
G
G
D000293:Adolescent; D000328:Adult; D000368:Aged; D001299:Audiometry; D001809:Blood Viscosity / Q000187:drug effects; D004907:Erythrocyte Deformability / Q000187:drug effects; D005260:Female; D003639:Hearing Loss, Sudden / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010431:Pentoxifylline / Q000494:pharmacology / Q000627:therapeutic use*; D011379:Prognosis; D013805:Theobromine / Q000031:analogs & derivatives*
D013805:Theobromine; D010431:Pentoxifylline
Surdités brusques: a propos de 19 cas. Résultats du traitement par la pentoxifylline. Intérêt de la mesure du temps de filtration erythrocytaire.