Integral membrane protein located in the apical complex of Plasmodium falciparum.
We describe the cloning of a novel antigen of Plasmodium falciparum which contains a hydrophobic domain typical of an integral membrane protein. This antigen is designated apical membrane antigen 1 because it appears to be located in the apical complex. Apical membrane antigen 1 appears to be transported to the merozoite surface near the time of schizont rupture.
Peterson
M G
MG
Walter and Eliza Hall Institute of Medical Research, Post Office Royal Melbourne Hospital, Victoria, Australia.
Marshall
V M
VM
Smythe
J A
JA
Crewther
P E
PE
Lew
A
A
Silva
A
A
Anders
R F
RF
Kemp
D J
DJ
D000595:Amino Acid Sequence; D000818:Animals; D000953:Antigens, Protozoan / Q000235:genetics*; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics*; D008565:Membrane Proteins / Q000235:genetics*; D008969:Molecular Sequence Data; D008970:Molecular Weight; D010963:Plasmodium falciparum / Q000235:genetics / Q000276:immunology*
D000953:Antigens, Protozoan; D008565:Membrane Proteins; D004247:DNA