Amoxapine-induced neuroleptic malignant syndrome.
Amoxapine is a second-generation antidepressant possessing significant dopamine-blocking activity and extra-pyramidal side effects. The occurrence of neuroleptic malignant syndrome is described in a patient treated with amoxapine. The syndrome resolved rapidly following discontinuation of the drug. Older patients may be particularly at risk for this adverse reaction with amoxapine.
Madakasira
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S
Psychiatry Service, Veterans Administration Medical Center, Dayton, OH 45428.
D000657:Amoxapine / Q000009:adverse effects*; D001714:Bipolar Disorder / Q000188:drug therapy; D003989:Dibenzoxazepines / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009459:Neuroleptic Malignant Syndrome / Q000209:etiology*
D003989:Dibenzoxazepines; D000657:Amoxapine