title: 125 years of experimental heat shock research: historical roots of a discipline.
abstract: The history of experimental heat shock research over the last 125 years is briefly, outlined. Starting with reports on the upper temperature limits of plant survival (1864) and on the spontaneous regression of skin cancer after a severe local inflammation (1866), studies on the heat shock response today are a major field of modern cell biology and include all types of prokaryotic and eukaryotic organisms.
authors.affiliation: Akademie der Wissenschaften der DDR, Institut für Biochemie der Pflanzen, Halle, German Democratic Republic.
authors.forename: L
authors.initials: L
authors.lastname: Nover
mesh_terms: D000818:Animals; D005334:Fever / Q000503:physiopathology; D006360:Heat-Shock Proteins / Q000502:physiology; D049672:History, 19th Century; D049673:History, 20th Century; D006358:Hot Temperature; D006801:Humans; D006979:Hyperthermia, Induced / Q000266:history; D010827:Physiology / Q000266:history*
chemical_list: D006360:Heat-Shock Proteins