title: Arctic adaptation in reindeer. The energy saving of a hemoglobin.
abstract: Previous results [(1988) Arct. Med. Res. 47, 83-88] have shown that hemoglobin from reindeer is characterized by a low overall heat of oxygenation. This particular aspect has been investigated further in a series of precise oxygen equilibrium experiments. The results obtained show a peculiar dependence of the temperature effect on the fractional saturation of hemoglobin with oxygen, which could be regarded as a very interesting case of molecular adaptation to extreme environmental conditions.
authors.affiliation: Department of Experimental Medicine and Biochemical Sciences, II University of Rome, Italy.
authors.forename: B
authors.initials: B
authors.lastname: Giardina
authors.forename: O
authors.initials: O
authors.lastname: Brix
authors.forename: M
authors.initials: M
authors.lastname: Nuutinen
authors.forename: S
authors.initials: S
authors.lastname: el Sherbini
authors.forename: A
authors.initials: A
authors.lastname: Bardgard
authors.forename: G
authors.initials: G
authors.lastname: Lazzarino
authors.forename: S G
authors.initials: SG
authors.lastname: Condò
mesh_terms: D019794:2,3-Diphosphoglycerate; D000222:Adaptation, Physiological; D000818:Animals; D002712:Chlorides / Q000097:blood; D003080:Cold Temperature; D004163:Diphosphoglyceric Acids / Q000097:blood; D004734:Energy Metabolism; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010100:Oxygen / Q000097:blood; D011487:Protein Conformation; D012053:Reindeer / Q000502:physiology*; D013696:Temperature; D013816:Thermodynamics
chemical_list: D002712:Chlorides; D004163:Diphosphoglyceric Acids; D006454:Hemoglobins; D019794:2,3-Diphosphoglycerate; D010100:Oxygen