title: [Farmer's lung: IgG-subclass reactivities against thermophilic actinomycetes].
abstract: IgG subclass reactivities of patients suffering from farmer's lung, healthy family members and blood donors were tested for specific binding to Micropolyspora faeni extract by means of immunoblot techniques (IEF-Print, Western Blot). In patients' sera IgG1 and IgG2 had shown the strongest reactivities while IgG3- and IgG4-reactivities were not found in all cases. Strong IgG2-reactivities against acidic proteins (pl 3-5) of M. faeni seem to distinguish between patients and exposed or not exposed controls, respectively.
authors.affiliation: Forschungsinstitut Borstel, Medizinische Klinik.
authors.forename: G
authors.initials: G
authors.lastname: Reese
authors.forename: W M
authors.initials: WM
authors.lastname: Becker
authors.forename: M
authors.initials: M
authors.lastname: Schlaak
mesh_terms: D015153:Blotting, Western; D005203:Farmer's Lung / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis / Q000145:classification / Q000276:immunology*; D007525:Isoelectric Focusing; D008848:Micromonosporaceae / Q000276:immunology*
chemical_list: D007074:Immunoglobulin G
vernacular_title: Farmerlunge: IgG-Subklassenreaktivitäten gegen thermophile Aktinomyzeten.