Intra-epidermal neutrophilic IgA dermatosis with colitis.
We report the association of an intra-epidermal blistering disease of the skin with colitis. Both the skin and large bowel epithelium were infiltrated by neutrophils and eosinophils, and showed intra-epithelial deposition of IgA in an intercellular pattern. The colitis and the blisters responded well to treatment with dapsone.
Wright
S
S
Department of Dermatology, London Hospital, U.K.
Phillips
T
T
Ryan
J
J
Leigh
I M
IM
D000368:Aged; D003092:Colitis / Q000150:complications* / Q000276:immunology / Q000473:pathology; D004817:Epidermis / Q000276:immunology / Q000473:pathology; D004848:Epithelium / Q000276:immunology / Q000473:pathology; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D009504:Neutrophils / Q000473:pathology*; D012007:Rectum / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000150:complications* / Q000276:immunology / Q000473:pathology
D007070:Immunoglobulin A