title: Perinatal cocaine intoxication.
abstract: This report describes a case in which cocaine abuse during pregnancy was related temporally to abruptio placentae, preterm labour and to rapid delivery. The neonate developed respiratory distress with features of persistent pulmonary hypertension of the newborn and also signs of neurological dysfunction. He was managed by supportive therapy and has been followed-up to nine months of age. Perinatal cocaine intoxication, either directly or indirectly, is discussed as a cause of his cardiorespiratory and neurological maladaptation. As cocaine abuse appears to be an escalating problem in Australia, increased public awareness of the dangers of both acute and long-term abuse of the drug is seen as a priority in preventive care.
authors.affiliation: Royal Prince Alfred Hospital, Camperdown, NSW.
authors.forename: E
authors.initials: E
authors.lastname: Collins
authors.forename: R J
authors.initials: RJ
authors.lastname: Hardwick
authors.forename: H
authors.initials: H
authors.lastname: Jeffery
mesh_terms: D000328:Adult; D003042:Cocaine; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008691:Methadone / Q000627:therapeutic use; D009357:Neonatal Abstinence Syndrome / Q000209:etiology*; D010102:Oxygen Inhalation Therapy; D011247:Pregnancy; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology* / Q000628:therapy; D019966:Substance-Related Disorders
chemical_list: D003042:Cocaine; D008691:Methadone