[Effect of vitamin E on the function of blood platelets in patients with diabetes mellitus].
An effect of vitamin E on blood platelets functioning was studied in 39 patients with diabetes mellitus type 1. Control group included 20 healthy blood donors. Vitamin E in a daily dose of 1000 mg produced statistically significant decrease in platelets aggregation, number of circulating platelet aggregates and release of the platelet factory 4 in diabetics after 7 days of treatment. No adverse reactions were seen in any patient treated with vitamin E. The obtained results indicate that vitamin E inhibits increased platelets activity in the patients with diabetes mellitus type 1 and does not exert toxic reactions during the treatment.
Dmoszyńska-Giannopoulou
A
A
Roliński
J
J
Sokołowska
B
B
Nowakowski
A
A
D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000187:drug effects*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology; D010978:Platelet Factor 4 / Q000378:metabolism; D014810:Vitamin E / Q000494:pharmacology*
D010975:Platelet Aggregation Inhibitors; D014810:Vitamin E; D010978:Platelet Factor 4
Wpływ witaminy E na czynność krwinek płytkowych u chorych na cukrzyce.