title: Magnetic resonance and computed tomographic image-directed stereotaxy for animal research.
abstract: Current stereotactic frames for animal experimentation presume normal intracranial anatomy for atlas-directed probe placement. This is an invalid assumption for animal brain tumor models, where distortions of cerebral anatomy make image-directed stereotaxy necessary. To address this need, an accurate and reproducible magnetic resonance and computed tomographic compatible image-directed stereotactic apparatus for animal experimentation is presented.
authors.affiliation: Department of Neurosurgery, Vanderbilt University, Nashville, Tenn.
authors.forename: R J
authors.initials: RJ
authors.lastname: Maciunas
authors.forename: R L
authors.initials: RL
authors.lastname: Galloway
mesh_terms: D000818:Animals; D001932:Brain Neoplasms / Q000175:diagnosis / Q000628:therapy; D002415:Cats; D004285:Dogs; D004867:Equipment Design; D008279:Magnetic Resonance Imaging; D013238:Stereotaxic Techniques / Q000295:instrumentation*; D014057:Tomography, X-Ray Computed