Insect baculoviruses: powerful gene expression vectors.
Baculovirus vectors have proven useful in producing high levels of biologically active eukaryotic proteins and providing cellular fractions which are enriched in the protein of interest. Expression occurs in infected insect cells which also provide a suitable environment for post-translational modification and folding of the protein product. Stable baculovirus vectors can be constructed rapidly with a minimum of viral manipulation.
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D004267:DNA Viruses / Q000235:genetics*; D015967:Gene Expression Regulation, Viral / Q000502:physiology*; D005822:Genetic Vectors / Q000502:physiology*; D007304:Insect Viruses / Q000235:genetics*; D010957:Plasmids / Q000235:genetics; D011499:Protein Processing, Post-Translational / Q000502:physiology*