Metabolic considerations in the treatment of the black hypertensive.
Hypertension and its cardiovascular consequences are both common and potentially devastating among black Americans. Recent evidence suggests that not all antihypertensive agents have similar efficacy in hypertensive patients, nor do all convey the same benefit in terms of reducing the risk of cardiovascular disease. This review considers the efficacy of various antihypertensive agents in blacks, with particular reference to the impact of these agents on cardiovascular disease risk factors and on associated diseases often encountered in black hypertensives. Emphasis is placed on the use of therapeutic approaches other than diuretics alone or in combination with other antihypertensive agents from the vantage point of efficacy and enhancement of cardiovascular and metabolic benefits.
Weinberger
M H
MH
Hypertension Research Center, Indiana University School of Medicine, Indianapolis 46202-5111.
D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D044383:Black People; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D004232:Diuretics / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000378:metabolism; D001741:Black or African American
D000806:Angiotensin-Converting Enzyme Inhibitors; D002121:Calcium Channel Blockers; D004232:Diuretics