Postischemic changes of calcium and endogenous antagonist in the rat hippocampus studied by proton-induced X-ray emission analysis.
Proton-induced X-ray emission analysis (PIXE) was applied to determine ischemia-induced changes in the content of calcium, iron, nickel and zinc in the rat hippocampus. After 30 min or 2 h reperfusion following 20 min of ischemia, the nickel content decreased and the zinc content increased. The calcium content was increased 50% after 30 min but was normal after 2 h reperfusion.
Tsuda
T
T
Department of Neurology, Tohoku University School of Medicine, Sendai, Japan.
Kogure
K
K
Ishii
K
K
Orihara
H
H
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D006624:Hippocampus / Q000378:metabolism* / Q000503:physiopathology; D002546:Ischemic Attack, Transient / Q000378:metabolism*; D008297:Male; D009532:Nickel / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013052:Spectrometry, X-Ray Emission; D015032:Zinc / Q000378:metabolism*
D009532:Nickel; D015032:Zinc; D002118:Calcium