Variation of vascular density within and between tumors of the uterine cervix and its predictive value for radiotherapy.
Vascular density in different regions of a number of uterine cervix carcinomas was determined by morphometric analysis of stained histologic sections. Variance analysis indicated a larger inter- than intra-tumoral inhomogeneity of the vasculature, suggesting a certain individual vascularization pattern in these tumors. As indicated by a retrospective study of archival biopsies, this pattern has a predictive value in regard to the efficacy of radiotherapy.
Révész
L
L
Department of Tumor Biology II, Karolinska Institute, Stockholm, Sweden.
Siracka
E
E
Siracky
J
J
Delides
G
G
Pavlaki
K
K
D002294:Carcinoma, Squamous Cell / Q000098:blood supply* / Q000532:radiotherapy; D005260:Female; D006801:Humans; D011379:Prognosis; D002583:Uterine Cervical Neoplasms / Q000098:blood supply* / Q000532:radiotherapy