[Effect of the stimulation of lymphocyte adrenoreceptors on antitumor immunity in vitro].
It was found that the stimulating effect of alpha-adrenomimetic mesatone in the test of lymphocyte adhesion inhibition in patients with rectum cancer in vitro was eliminated by beta-adrenergic blocker phentolamine and the inhibitory effect of beta-adrenergic antagonist propranolol. It was shown in vitro that lymphocyte chemoreceptor sensitivity to the stimulating effect of mesatone decreased and sensitivity to the inhibitory effect of isadrine increased in patients with advanced stages of rectum cancer.
Kharkevich
D D
DD
Kadagizde
Z G
ZG
D002448:Cell Adhesion / Q000187:drug effects; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007545:Isoproterenol / Q000494:pharmacology; D008213:Lymphocyte Activation / Q000187:drug effects*; D010646:Phentolamine / Q000494:pharmacology; D010656:Phenylephrine / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D011941:Receptors, Adrenergic / Q000187:drug effects* / Q000276:immunology; D012004:Rectal Neoplasms / Q000276:immunology*; D013268:Stimulation, Chemical
D011941:Receptors, Adrenergic; D010656:Phenylephrine; D011433:Propranolol; D007545:Isoproterenol; D010646:Phentolamine
Vliianie stimuliatsii adrenoretseptorov limfotsitov na protivoopukholevyĭ immunitet in vitro.