title: Chorionic villus sampling--short-term versus long-term culture in a subtle 2; 18 translocation.
abstract: Prenatal diagnosis on chorionic villous tissue was performed for a woman with the karyotype 46,XX,t(2;18)(q32;q12)--a subtle 'difficult' translocation. The case illustrates the necessity of good quality cytogenetics for accurate prenatal diagnosis. For chorionic villi this can be obtained only with long-term culture.
authors.affiliation: Cytogenetics Unit, Oliver Latham Laboratory, Department of Health, N.S.W., Australia.
authors.forename: A
authors.initials: A
authors.lastname: Smith
authors.forename: M
authors.initials: M
authors.lastname: Cohen
authors.forename: G
authors.initials: G
authors.lastname: den Dulk
authors.forename: A
authors.initials: A
authors.lastname: Guirguis
mesh_terms: D015193:Chorionic Villi Sampling / Q000379:methods*; D002887:Chromosomes, Human, Pair 18; D002889:Chromosomes, Human, Pair 2; D005260:Female; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy; D013997:Time Factors; D014178:Translocation, Genetic