Legionnaires' disease in a patient with rheumatoid arthritis treated with cyclosporine.
We report a patient with long-standing rheumatoid arthritis (RA) treated with cyclosporine A; she developed a flare of her arthritis and evidence of vasculitis, cavitary pulmonary disease, nephritis and hepatitis, and was found to have Legionella pneumophila serotype I infection. Cyclosporine is a relatively new and investigational therapy in RA. Thus, it is important that any unusual complications in patients with RA treated with cyclosporine should be documented.
Pillemer
S R
SR
National Institutes of Health, Bethesda, MD 20892.
Webb
D
D
Yocum
D E
DE
D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy; D003524:Cyclosporins / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007877:Legionnaires' Disease / Q000209:etiology*; D008875:Middle Aged; D009894:Opportunistic Infections / Q000209:etiology*
D003524:Cyclosporins