title: [Primary failure of pericardial valvular heterografts].
abstract: From July 1981 to October 1984, 79 Hancock pericardial valves were implanted in 74 patients surviving the hospital period and with a mean age of 64.2 years. Fifty-two patients underwent aortic valve replacement, 16 had mitral valve replacement, 5 bad a double replacement and 19 associated procedures were performed. The mean survival is 48 months. Until 1st June 1987, 11 primary failures have required reoperation (14.9%), 4 in the mitral position (4.6% patient-years), 7 in the aortic position (3.01% patient-years). The time to reoperation was 48.4 months for the aortic orifice and 36.5 months for the mitral orifice. The lesions most frequently encountered were tears (7 cases), calcifications (5 cases) and stretching of valvular tissue (2 cases); two patients died during the postoperative phase of this operation. Despite the small number of patients followed, this series demonstrates of high incidence of dysfunction due to primary tissue degeneration as, after the 5th year, the actuarial rate of absence of primary lesion is 85.3 +/- 8% with no significant difference between the aortic and the mitral orifices, although dysfunction appears to occur more rapidly in mitral prostheses. These results are much less favourable than those obtained with Ionescu bioprostheses in the aortic position of those obtained with porcine bioprostheses in either position. This justifies very regular clinical and echocardiographic follow-up of patients with Hancock pericardial valvular heterografts.
authors.forename: G
authors.initials: G
authors.lastname: Fournial
authors.forename: M
authors.initials: M
authors.lastname: Sauer
authors.forename: M
authors.initials: M
authors.lastname: Fauvel
authors.forename: E
authors.initials: E
authors.lastname: Henry
authors.forename: E
authors.initials: E
authors.lastname: Pourrat
authors.forename: M
authors.initials: M
authors.lastname: Bernies
authors.forename: P
authors.initials: P
authors.lastname: Bernadet
authors.forename: J
authors.initials: J
authors.lastname: Marco
mesh_terms: D000206:Actuarial Analysis; D000293:Adolescent; D000328:Adult; D000368:Aged; D001021:Aortic Valve; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve; D010496:Pericardium; D011475:Prosthesis Failure; D014183:Transplantation, Heterologous
vernacular_title: Défaillance primitive des hétérogreffes valvulaires péricardiques.