[Effect of liposome-encapsulated pentacin on plutonium-239 excretion].
A study was made of the influence of pentacin, encapsulated in liposomes, on the excretion of monomeric plutonium-239 from dogs and albino rats. Pentacin in a liposomal form, in comparison with free pentacin, increased the excretion of plutonium in urine from a dog body by 23.5% when administered in 24 h, and by 28% when administered in 20 days; in rats, the excretion increase made 40% after the administration in 30 or 45 days.
Il'in
L A
LA
Ivannikov
A T
AT
Altukhova
G A
GA
Parfenova
I M
IM
Chelysheva
T V
TV
D000818:Animals; D004285:Dogs; D004337:Drug Carriers; D005260:Female; D008081:Liposomes; D008297:Male; D004369:Pentetic Acid / Q000008:administration & dosage / Q000494:pharmacology*; D011005:Plutonium / Q000493:pharmacokinetics* / Q000652:urine; D051381:Rats; D013997:Time Factors; D014018:Tissue Distribution / Q000187:drug effects
D004337:Drug Carriers; D008081:Liposomes; D011005:Plutonium; D004369:Pentetic Acid
Vliianie pentatsina, inkapsulirovannogo v liposomakh, na vyvedenie plutoniia-239.