title: Clear cell thyroid cancer--undifferentiated type--an immunohistochemical and electron microscopical study.
abstract: Two cases of clear cell thyroid cancer are described. In both tumors immunohistochemical methods detected the presence of intracytoplasmic thyroglobulin that confirmed the follicular origin. Simultaneously performed electron microscopic studies visualized the accumulation of smooth surfaced, membrane coated vesicles of varying size in the cytoplasm. Bad prognosis predicted on the base of undifferentiated histological structure was confirmed by extended hematogenic metastases.
authors.affiliation: National Oncological Institute, Budapest, Hungary.
authors.forename: I
authors.initials: I
authors.lastname: Péter
authors.forename: I
authors.initials: I
authors.lastname: Besznyák
authors.forename: J
authors.initials: J
authors.lastname: Szántó
authors.forename: M
authors.initials: M
authors.lastname: Füzy
authors.forename: M
authors.initials: M
authors.lastname: Bodó
authors.forename: J
authors.initials: J
authors.lastname: Sugár
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000648:ultrastructure; D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000648:ultrastructure; D008207:Lymphatic Metastasis; D008854:Microscopy, Electron; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000556:secondary / Q000648:ultrastructure