Effects of triiodothyronine on insulin release from cultured neonatal and adult rat islets.
Insulin secretion from neonatal and adult rat islets maintained in culture for 7-9 days in the absence or in the presence of 10 nM T3 was measured. In both neonatal and adult islets T3 treatment tends to inhibit insulin secretion only in the absence or in the presence of low glucose concentrations.
Boschero
A C
AC
Departamento de Fisiologia e Biofísica, Universidade Estadual de Campinas, SP, Brasil.
Tombaccini
D
D
Atwater
I
I
D000818:Animals; D003470:Culture Media; D005947:Glucose / Q000378:metabolism*; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000378:metabolism*; D051381:Rats; D014284:Triiodothyronine / Q000494:pharmacology*
D003470:Culture Media; D007328:Insulin; D014284:Triiodothyronine; D005947:Glucose