[The role of IgA and IgA antigliadin antibodies in the diagnosis and management of celiac disease].
The authors reports the results of ELISA IgG and IgA antigliadin antibodies measurements in a study of 271 serum samples proceeding from celiac patients (with and without gluten containing diet) and control subjects. IgA antigliadin antibody measurement had the most specificity and positive predictive value, IgG antigliadin antibody measurement had the most sensitivity and negative predictive value. Our results point out that antigliadin antibodies are helpful in the diagnosis and management of celiac disease. Un the same manner, antigliadin antibodies are helpful to evaluate the adherence of patients to gluten-free diet.
Torregrosa Sánchez
R
R
Hospital General, Servicio de Análisis Clínicos y Servicio de Pediatría, Valencia.
Polo Martín
P
P
Calabuig Sánchez
M
M
Tomás Rates
C
C
Vilar Escrigas
P
P
Farre Massip
C
C
Varea Calderón
V
V
Alvarez Angel
V
V
Sanchís-Bayarri Vaillant
V
V
D002446:Celiac Disease / Q000175:diagnosis / Q000178:diet therapy / Q000276:immunology*; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay; D005903:Gliadin / Q000276:immunology*; D005983:Glutens / Q000009:adverse effects*; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology*; D007074:Immunoglobulin G / Q000276:immunology*; D010940:Plant Proteins / Q000276:immunology*
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D010940:Plant Proteins; D005983:Glutens; D005903:Gliadin
Importancia de los anticuerpos antigliadina de tipo IgA e IgG en el diagnóstico y seguimiento de la E. celíaca.