title: [Variation of C3 in ascitic fluid from cirrhotic patients subjected to intestinal sterilization or selective intestinal decontamination].
abstract: Patients with liver cirrhosis with ascites and low levels of C3 and Total Proteins in ascitic fluid show a greater predisposition to the development of spontaneous bacterial peritonitis. The variation of C3 and Total Proteins levels in ascitic fluid in two groups of patients with liver cirrhosis was studied. Group I (n = 14) underwent intestinal sterilization (n = 7) or selective intestinal decontamination (= 7). Group II was a control. A statistically significant increase in C3 (p less than 0.01) and Total Proteins (p less than 0.015) levels in ascitic fluid in Group I patients was found. There were no changes in the control group. The incidence of side effects was higher in those patients who underwent intestinal sterilization. Our results suggest that selective intestinal decontamination may be useful as a prophylactic measure against spontaneous bacterial peritonitis in those patients with liver cirrhosis at high risk of infection by increasing the bactericidal capacity of ascitic fluid.
authors.forename: G
authors.initials: G
authors.lastname: Soriano
authors.forename: M
authors.initials: M
authors.lastname: Teixidó
authors.forename: C
authors.initials: C
authors.lastname: Guarner
authors.forename: J
authors.initials: J
authors.lastname: Such
authors.forename: J C
authors.initials: JC
authors.lastname: Espinós
authors.forename: S
authors.initials: S
authors.lastname: Sainz
authors.forename: J
authors.initials: J
authors.lastname: Enríquez
authors.forename: J L
authors.initials: JL
authors.lastname: Rodríguez
authors.forename: F
authors.initials: F
authors.lastname: Vilardell
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001202:Ascitic Fluid / Q000032:analysis*; D001424:Bacterial Infections; D003176:Complement C3 / Q000032:analysis*; D003666:Decontamination / Q000379:methods; D005260:Female; D006801:Humans; D007422:Intestines / Q000187:drug effects / Q000382:microbiology; D008103:Liver Cirrhosis / Q000150:complications* / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D010538:Peritonitis / Q000209:etiology / Q000382:microbiology; D011506:Proteins / Q000032:analysis; D011897:Random Allocation; D013242:Sterilization / Q000379:methods
chemical_list: D000900:Anti-Bacterial Agents; D003176:Complement C3; D011506:Proteins
vernacular_title: Variación del C3 en líquido ascítico de pacientes cirróticos sometidos a esterilización intestinal o a descontaminación intestinal selectiva.