[A method for the standardized in vitro testing of biomaterials with bacterial cultures].
The preclinical investigation of potential biomaterials requires a comprehensive profile of biological parameters. In the present paper a new in vitro test will be described which allows a standardized testing of the effect of biomaterials on the proliferation of bacteria. For this test eluates of solid materials, granulates or powders of potential biomaterials were prepared. These eluates were mixed a bacterial culture containing a definite number of microbes and incubated for 4-20 hours at 37 degrees C. The effect on bacterial growth was determined photometrically.
Schubert
R
R
Sektion Stomatologie, Bereichs Medizin, Humboldt-Universität zu Berlin.
Mehl
M
M
Kissig
B
B
Widera
P
P
D001672:Biocompatible Materials / Q000494:pharmacology*; D003470:Culture Media; D008422:Materials Testing / Q000379:methods* / Q000592:standards; D013295:Streptococcus mutans / Q000254:growth & development*
D001672:Biocompatible Materials; D003470:Culture Media
Verfahren zur standardisierten In-vitro-Testung von Biomaterialien mit Bakterienkulturen.