title: Adrenal masses: evaluation with fast gradient-echo MR imaging and Gd-DTPA-enhanced dynamic studies.
abstract: Fast gradient-echo magnetic resonance (MR) imaging of 38 adrenal masses with proved diagnosis was performed during suspended respiration with various repetition times (TRs), echo times (TEs), and flip angles. Dynamic perfusion studies after gadolinium diethylenetriamine-pentaacetic acid (DTPA) administration were performed by repeated imaging at short time intervals. With more T2 weighting (TR = 60 msec, TE = 30 msec, and flip angle = 15 degrees), malignant tumors and pheochromocytomas had a significantly higher relative signal intensity than adenomas; overlap of signal intensity led to equivocal findings in nine cases. After administration of Gd-DTPA, adenomas showed only mild enhancement and quick washout; malignant tumors and pheochromocytomas showed strong enhancement and slower washout. Five of the nine cases that were equivocal in precontrast images could thus be correctly classified. In addition to this improved classification of adrenal masses, fast, dynamic contrast material-enhanced MR imaging resulted in a reduction in total examination time.
authors.affiliation: Department of Radiology, University of Cologne Medical School, Federal Republic of Germany.
authors.forename: G P
authors.initials: GP
authors.lastname: Krestin
authors.forename: W
authors.initials: W
authors.lastname: Steinbrich
authors.forename: G
authors.initials: G
authors.lastname: Friedmann
mesh_terms: D000236:Adenoma / Q000175:diagnosis; D000310:Adrenal Gland Neoplasms / Q000175:diagnosis* / Q000556:secondary; D000368:Aged; D002277:Carcinoma / Q000175:diagnosis / Q000556:secondary; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008297:Male; D009942:Organometallic Compounds; D004369:Pentetic Acid; D010673:Pheochromocytoma / Q000175:diagnosis; D014057:Tomography, X-Ray Computed
chemical_list: D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA