title: Superwarfarin poisoning.
abstract: Superwarfarins consist of two classes of compounds, the 4-hydroxycoumarins and the indandiones. These compounds have replaced warfarin as an anticoagulant rodenticide. This article is a summary of the clinical effects produced by accidental and deliberate ingestions of superwarfarins. Most accidental ingestions occur in childhood and result in a benign outcome. Deliberate overdoses usually involve repeated ingestions of large quantities of superwarfarins that have resulted in prolonged laboratory evidence of interference with clotting; serious bleeding has been rare. This article suggests an approach to the management of patients with accidental and deliberate anticoagulant rodenticide ingestions.
authors.affiliation: Department of Pharmacy, Francis Scott Key Medical Center, Baltimore, MD.
authors.forename: B
authors.initials: B
authors.lastname: Katona
authors.forename: S
authors.initials: S
authors.lastname: Wason
mesh_terms: D015110:4-Hydroxycoumarins / Q000506:poisoning; D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D012378:Rodenticides / Q000506:poisoning*
chemical_list: D015110:4-Hydroxycoumarins; D012378:Rodenticides