[Localization of the action of furosemide and triamterene in the nephron by means of correlating their pharmacokinetics and pharmacodynamics].
A comparative correlation of pharmacokinetics and pharmacodynamics of furosemide and triamterene was used to establish localization of the action of the former diuretic on the basal membrane and the action of the latter on the lumenal membrane.
Lebedev
A A
AA
Munina
I I
II
D000818:Animals; D004285:Dogs; D005665:Furosemide / Q000032:analysis / Q000493:pharmacokinetics / Q000494:pharmacology*; D009318:Natriuresis / Q000187:drug effects; D009399:Nephrons / Q000187:drug effects* / Q000378:metabolism; D013997:Time Factors; D014223:Triamterene / Q000032:analysis / Q000493:pharmacokinetics / Q000494:pharmacology*
D005665:Furosemide; D014223:Triamterene
Izuchenie lokalizatsii deĭstviia furosemida i triamterena v nefrone metodom korreliatsii farmakokinetiki i farmakodinamiki.