Long-term survival of patients with advanced ovarian carcinoma treated with cisplatin-based chemotherapy regimens.
Long-term results of different studies employing cisplatin-based chemotherapy in advanced ovara in cancer are just beginning to be published. Available data suggest that the rate of relapse decreases but does not cease, and the question of whether cisplatin-based chemotherapy results in an improved cure in advanced ovarian cancer is still unanswered. The long-term survival results published so far are reviewed. Furthermore the impact of other drugs, especially doxorubicin, in addition to cisplatin is discussed.
De Pree
N
N
Department of Gynecology and Obstetrics, Laurentius Hospital, Roermond, The Netherlands.
Wils
J
J
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D010752:Phosphoramide Mustards / Q000008:administration & dosage
D010752:Phosphoramide Mustards; D004317:Doxorubicin; D003520:Cyclophosphamide; D002945:Cisplatin