Comparison of the effects of general and epidural anaesthesia for caesarean section on the neurobehavioural responses of newborn infants.
Thirty-one neonates delivered by elective caesarean section were evaluated at the ages of 3 h, 1 day, 2 days and 4-5 days using Scanlon's Early Neonatal Neurobehavioural Scale and tests for orientation. Thirteen of the mothers received general anaesthesia and 18 epidural anaesthesia. All the mothers were healthy and not in labour. All the neonates weighed 2500 g or more and had Apgar scores of 7 or more at 1, 5 and 15 min. The neonates delivered with epidural anaesthesia scored significantly lower on rooting at the age of 3 h than those delivered with general anaesthesia, but the latter scored significantly lower on habituation to sound and orientation to both animate and inanimate visual stimuli. General anaesthesia seemed to depress the infants' interactive processes (orientation items), and their ability to make an appropriate response to repetitive stimuli (habituation) more than did epidural anaesthesia, indicating greater global depression. This depression was short-lived, however, and there were no differences between the groups on any of the parameters after 24 h.
Kangas-Saarela
T
T
Department of Anaesthesiology, University of Oulu, Finland.
Koivisto
M
M
Jouppila
R
R
Jouppila
P
P
Hollmén
A
A
D000328:Adult; D000767:Anesthesia, Epidural; D000768:Anesthesia, General; D000773:Anesthesia, Obstetrical; D001519:Behavior / Q000502:physiology; D002585:Cesarean Section; D005260:Female; D006801:Humans; D007231:Infant, Newborn / Q000502:physiology* / Q000523:psychology; D008297:Male; D009460:Neurologic Examination; D011247:Pregnancy