Orosomucoid (ORM) typing by isoelectric focusing: description of two new alleles in a German population and thermostability in bloodstains.
The genetic polymorphism of serum orosomucoid (ORM) was studied in 168 unrelated German individuals using isoelectric focusing followed by immunoprinting. Two new alleles, tentatively designated ORM1*14 and ORM2*13, were identified. The method was successfully applied to demonstrate ORM1 types in dried bloodstains. Each type of ORM1 was also correctly determined in bloodstains heated at 130 degrees C for 30 min. The results indicated that ORM1 is a new powerful genetic marker system for the grouping of bloodstains.
Umetsu
K
K
Department of Forensic Medicine, Yamagata University School of Medicine, Japan.
Yuasa
I
I
Nishi
K
K
Brinkmann
B
B
Suzuki
T
T
D000483:Alleles; D001801:Blood Stains; D005787:Gene Frequency; D005828:Genetics, Population; D005860:Germany, West; D006801:Humans; D007525:Isoelectric Focusing; D009961:Orosomucoid / Q000235:genetics*; D010641:Phenotype; D011110:Polymorphism, Genetic
D009961:Orosomucoid