title: Substance abuse in pregnant women: recent experience at the Perinatal Center for Chemical Dependence of Northwestern Memorial Hospital.
abstract: Drug abuse during pregnancy is associated with adverse perinatal outcome. Patterns of abuse have changed in recent years with the increasing popularity of cocaine. We compared pregnancy outcome data from 137 women receiving prenatal care in the Perinatal Center for Chemical Dependence of Northwestern Memorial Hospital with those of matched controls. Among drug-using women, the mean gestational age at delivery and mean birth weight were significantly lower than those of controls. In addition, study pregnancies were more frequently complicated by the need for antenatal hospitalization, preterm delivery, low birth weight (less than 2500 g), and abruptio placentae.
authors.affiliation: Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinois.
authors.forename: L G
authors.initials: LG
authors.lastname: Keith
authors.forename: S
authors.initials: S
authors.lastname: MacGregor
authors.forename: S
authors.initials: S
authors.lastname: Friedell
authors.forename: M
authors.initials: M
authors.lastname: Rosner
authors.forename: I J
authors.initials: IJ
authors.lastname: Chasnoff
authors.forename: J J
authors.initials: JJ
authors.lastname: Sciarra
mesh_terms: D000328:Adult; D001034:Apgar Score; D005260:Female; D006679:HIV Seropositivity / Q000453:epidemiology; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D008297:Male; D007752:Obstetric Labor, Premature / Q000453:epidemiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D011256:Pregnancy Outcome; D011619:Psychotropic Drugs; D019966:Substance-Related Disorders / Q000453:epidemiology*
chemical_list: D011619:Psychotropic Drugs