title: Contact allergy to colophony. (IV). The sensitizing potency of commercial products. An investigation of French and American modified colophony derivatives.
abstract: The sensitizing capacity of 15 commercial colophony products was studied experimentally in guinea pigs. The study included 8 French and 6 American colophony derivatives as well as French tall oil colophony. The results indicate that tall oil colophony is the strongest sensitizing material within the tested group and that the maleic-modified products and the zinc-calcium-resinate are moderate sensitizers. Most of the modified products show a higher sensitizing capacity than the genuine resin acids themselves. Cross-reactions between the resin acids and the derivatives are uncommon. Therefore, patch testing with high concentrations of colophony (e.g., 60%) will not help to detect patients with colophony-derivative allergy.
authors.affiliation: Department of Dermatology, University Hospital, Hamburg, FRG.
authors.forename: B M
authors.initials: BM
authors.lastname: Hausen
authors.forename: S
authors.initials: S
authors.lastname: Jensen
authors.forename: J
authors.initials: J
authors.lastname: Mohnert
mesh_terms: D000818:Animals; D003877:Dermatitis, Contact / Q000209:etiology*; D006168:Guinea Pigs; D010938:Plant Oils; D012116:Resins, Plant / Q000633:toxicity*
chemical_list: D010938:Plant Oils; D012116:Resins, Plant; C482568:tall oil; C013893:rosin