title: Idiopathic infantile arterial calcification with cardiac, renal and central nervous system involvement.
abstract: Idiopathic infantile arterial calcification was diagnosed in a 2 week old infant with failure to thrive associated with neurological, renal and cardiac signs. Therapy with diphosphonate resulted in a complete resolution of vascular calcifications. At the age of 2 years the child is doing well but requires medical treatment for arterial hypertension.
authors.affiliation: Department of Pediatrics Renal Unit, University of Leuven, Belgium.
authors.forename: M
authors.initials: M
authors.lastname: Van Dyck
authors.forename: W
authors.initials: W
authors.lastname: Proesmans
authors.forename: E
authors.initials: E
authors.lastname: Van Hollebeke
authors.forename: G
authors.initials: G
authors.lastname: Marchal
authors.forename: P
authors.initials: P
authors.lastname: Moerman
mesh_terms: D002114:Calcinosis / Q000473:pathology* / Q000628:therapy; D002540:Cerebral Cortex / Q000473:pathology*; D002675:Child, Preschool; D004164:Diphosphonates / Q000008:administration & dosage; D005500:Follow-Up Studies; D006333:Heart Failure / Q000473:pathology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007669:Kidney Calculi / Q000473:pathology*; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000473:pathology*; D014057:Tomography, X-Ray Computed
chemical_list: D004164:Diphosphonates