Carcinoembryonic antigen: function in metastasis by human colorectal carcinoma.
Carcinoembryonic antigen (CEA) is a glycoprotein that has been useful as a tumor marker to predict recurrence in gastrointestinal malignancies, but whose biological function has not been elucidated. With the recent evidence that CEA is a member of the immunoglobulin supergene family, CEA may be involved in intercellular recognition and binding. This review examines the role that CEA plays in the development of metastases by colorectal carcinoma.
Jessup
J M
JM
Department of Surgery, University of Texas M.D. Anderson Cancer Center, Houston.
Thomas
P
P
D000818:Animals; D002272:Carcinoembryonic Antigen / Q000502:physiology*; D015179:Colorectal Neoplasms / Q000473:pathology; D006801:Humans; D009362:Neoplasm Metastasis
D002272:Carcinoembryonic Antigen