title: Stopped-flow--photometric and kinetic--fluorimetric methods for the determination of thyroid hormones in tablets.
abstract: The catalytic effect of thyroxine and triiodothyronine on the reaction between cerium(IV) and arsenic(III) was studied by using photometric and fluorimetric measurements. The kinetic - photometric studies were based on measurement of the decrease in absorbance of cerium(IV), whereas the rate of formation of fluorescent cerium(III) was measured in the kinetic - fluorimetric studies. A modular stopped-flow system was coupled to a spectrophotometer in order to develop stopped-flow methods for the determination of thyroxine and triiodothyronine. The proposed methods were compared and applied to the determination of these hormones in pharmaceutical preparations.
authors.forename: M
authors.initials: M
authors.lastname: Toledano
authors.forename: M C
authors.initials: MC
authors.lastname: Gutiérrez
authors.forename: A
authors.initials: A
authors.lastname: Gómez-Hens
authors.forename: D
authors.initials: D
authors.lastname: Pérez-Bendito
mesh_terms: D007700:Kinetics; D013050:Spectrometry, Fluorescence; D013607:Tablets; D013963:Thyroid Hormones / Q000032:analysis*
chemical_list: D013607:Tablets; D013963:Thyroid Hormones