title: [Antifungal effects in vitro of jasmon and some similar compounds. Structure-activity relationship].
abstract: The antimycotic activity in vitro of jasmon and 6 closely related substances has been tested against four different dermatophytes, Candida albicans, Pityrosporum ovale and Aspergillus fumigatus. Jasmon had the highest activity. Among the other substances tested only thiazolidines with a carbonyl function developed antifungal properties against dermatophytes. 2,4 thiazolidinedione at 450 ppm inhibits the growth of Trichophyton rubrum.
authors.forename: J
authors.initials: J
authors.lastname: Millet-Clerc
authors.forename: D
authors.initials: D
authors.lastname: Michel
authors.forename: J P
authors.initials: JP
authors.lastname: Chaumont
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D001232:Aspergillus fumigatus / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D066298:In Vitro Techniques; D008290:Malassezia / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D008864:Microsporum / Q000187:drug effects; D010946:Plants, Medicinal / Q000032:analysis; D013329:Structure-Activity Relationship; D014249:Trichophyton / Q000187:drug effects
chemical_list: D000935:Antifungal Agents
vernacular_title: Effects antifongiques in vitro de la jasmone et de quelques composés voisins. Relation structure-activité.