Application of high-performance liquid chromatographic analysis of scoparone and its metabolites in the study of cytochrome P450 differentiation in vitro.
Van Pelt
F N
FN
Institute of Veterinary Pharmacology, Pharmacy and Toxicology, University of Utrecht, The Netherlands.
Mennes
W C
WC
Hassing
I G
IG
Blaauboer
B J
BJ
D000818:Animals; D000959:Antihypertensive Agents / Q000032:analysis* / Q000378:metabolism; D001711:Biotransformation; D002478:Cells, Cultured; D002851:Chromatography, High Pressure Liquid; D003374:Coumarins / Q000032:analysis* / Q000378:metabolism; D006224:Cricetinae; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D008099:Liver / Q000201:enzymology / Q000378:metabolism; D051381:Rats; D012603:Scopoletin / Q000032:analysis / Q000378:metabolism; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet
D000959:Antihypertensive Agents; D003374:Coumarins; D003577:Cytochrome P-450 Enzyme System; C018145:scoparone; D012603:Scopoletin