title: [Changes in the sensomotor cortex of offspring after chronic intoxication with tobacco smoke through the mother-fetus system].
abstract: The state of the sensomotor cortex in the offspring of white non-inbred rats, "passively" smoking before mating, during mating and throughout pregnancy time has been investigated. The investigation performed in 14 age groups from the period of birth up to a relative morphological stability (age of 3 months), control and experimental rats (as a whole 281 animals) makes it possible to conclude that certain components of the tobacco smoke are accumulated in the offspring blood and continue to exercise a destructive influence on the neocortex during 2 weeks after birth. The consequence of chronic intoxication of the tobacco smoke through the system mother--fetus is expressed as diffuse and focal decrease of neurons nearly by 1/3 in the sensomotor cortex, especially in the V cytoarchitectonic layer.
authors.forename: R P
authors.initials: RP
authors.lastname: Kleshcheva
mesh_terms: D001812:Blood-Brain Barrier / Q000187:drug effects; D005260:Female; D006801:Humans; D008431:Maternal-Fetal Exchange; D010947:Plants, Toxic; D011247:Pregnancy; D012906:Smoke / Q000009:adverse effects*; D013003:Somatosensory Cortex / Q000187:drug effects* / Q000196:embryology; D014026:Nicotiana
chemical_list: D012906:Smoke
vernacular_title: Izmeneniia v sensomotornoĭ kore potomstva posle khronicheskoĭ intoksikatsii tabachnym dymom cherez sistemu mat'-plod.