A pseudoisochromosome 18q and an isodicentric chromosome 18.
A case of pseudoisochromosome 18q of prezygotic origin and a case of isodicentric chromosome 18 of postzygotic origin are presented to validate the differentiation between a true isochromosome and a pseudoisochromosome. This differentiation may be useful in elucidating the mechanism of the origin of an isochromosome.
Floore
C
C
Department of Pediatrics, University of Illinois, Chicago.
Robertson
A
A
Samuel
I
I
Williamson
N
N
McLeod
D R
DR
Hoganson
G
G
Hoo
J J
JJ
D000015:Abnormalities, Multiple / Q000235:genetics* / Q000473:pathology; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002887:Chromosomes, Human, Pair 18; D005260:Female; D006801:Humans; D007231:Infant, Newborn