[Efficacy of chemotherapy and immunochemotherapy in neuro-oncologic patients of various blood groups (ABO system)].
The efficacy of postoperative chemo- and immunochemotherapy was analysed according to the survival period from study of the catamnesis of patients who underwent operation for malignant (III-IV degree malignancy) gliomas. In analysing the efficacy of various schedules of combined treatment, the authors took into consideration the patients AB0 blood group because it is known that many antineoplastic antibiotics contain structures which are marked by cross reaction with the ABH isoantigens. The results of the study showed that the use of polychemotherapy and levamisole in neuro-oncological patients with A(II) and AB(IV) blood groups is promising. Levamisole and the antineoplastic antibiotic reumycin proved to be authentically effective in patients with A(II) blood group and ineffective in those with 0(I) blood group. The data obtained are recommended for use in individual selection of the schedule of chemo- and immunochemotherapy in patients with different AB0 blood group.
Romodanov
S A
SA
Gnedkova
I A
IA
Lisianyĭ
N I
NI
Glavatskiĭ
A Ia
AIa
D000017:ABO Blood-Group System; D000328:Adult; D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000097:blood / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D005910:Glioma / Q000097:blood / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D006801:Humans; D007978:Levamisole / Q000627:therapeutic use; D008875:Middle Aged; D014227:Triazines / Q000627:therapeutic use
D000017:ABO Blood-Group System; D000903:Antibiotics, Antineoplastic; D014227:Triazines; D007978:Levamisole; C009169:reumycin
Effektivnost' khimio- i immunokhimioterapii u neĭroonkologicheskikh bol'nykh s razlichnoĭ gruppoĭ krovi (sistema ABO).