Hyperthyroidism without elevated levels of thyroxine and triiodothyronine in a patient with pulmonary tuberculosis.
We have reported a case of toxic thyroid adenoma with low T3 and low T4 syndrome in a patient who received antituberculous drugs for active pulmonary tuberculosis. Search for thyroid-hormone-binding antibodies was negative. Thyroid lobectomy was done and histologic examination confirmed toxic thyroid adenoma; two months after operation the patient was clinically and biologically euthyroid. During the course of a severe nonthyroidal illness, normal thyroid hormone levels must be regarded as an indicator of hyperthyroidism. In addition, we believe that rifampin has a significant effect on thyroid function tests and results of thyroid physiology.
Archambeaud-Mouveroux
F
F
Department of Internal Medicine, Hospital Le Cluzeau, Limoges, France.
Dejax
C
C
DeBuhan
B
B
Bonnaud
F
F
D000236:Adenoma / Q000097:blood / Q000150:complications*; D000368:Aged; D000995:Antitubercular Agents / Q000009:adverse effects; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood / Q000209:etiology; D013964:Thyroid Neoplasms / Q000097:blood / Q000150:complications*; D013974:Thyroxine / Q000097:blood*; D014284:Triiodothyronine / Q000097:blood*; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000188:drug therapy
D000995:Antitubercular Agents; D014284:Triiodothyronine; D013974:Thyroxine