Patients with hereditary fructose intolerance have normal erythrocyte aldolase activity.
Erythrocyte fructose 1,6-bisphosphate aldolase (EC 4.1.2.13) activity was measured in eight children and adults with hereditary fructose intolerance and found to be normal when compared with eleven healthy controls. Therefore, hereditary fructose intolerance cannot be diagnosed by assaying red blood cell aldolase.
Gitzelmann
R
R
Department of Pediatrics, University of Zurich, Switzerland.
Steinmann
B
B
Tuchschmid
P
P
D000293:Adolescent; D000328:Adult; D002648:Child; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D005633:Fructose Intolerance / Q000097:blood / Q000201:enzymology*; D015318:Fructose Metabolism, Inborn Errors / Q000201:enzymology*; D005634:Fructose-Bisphosphate Aldolase / Q000097:blood*; D006801:Humans; D008297:Male
D005634:Fructose-Bisphosphate Aldolase