Radiation-induced sarcoma of the thyroid.
A 23-year-old white man presented with a thyroid mass 12 years after receiving high-dose radiotherapy for a T2 and N1 lymphoepithelioma of the nasopharynx. Following subtotal thyroidectomy, a histopathologic examination revealed liposarcoma of the thyroid gland. The relationship between sarcomas and irradiation is described and Cahan and colleagues' criteria for radiation-induced sarcomas are reviewed. To our knowledge, we are presenting the first such case of a radiation-induced sarcoma of the thyroid gland.
Griem
K L
KL
Department of Therapeutic Radiology, Rush-Presbyterian-St Luke's Medical Center, Chicago, IL 60612.
Robb
P K
PK
Caldarelli
D D
DD
Templeton
A C
AC
D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D002648:Child; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D006801:Humans; D008080:Liposarcoma / Q000209:etiology*; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000532:radiotherapy; D009381:Neoplasms, Radiation-Induced; D011867:Radioisotope Teletherapy / Q000009:adverse effects*; D011879:Radiotherapy Dosage; D013964:Thyroid Neoplasms / Q000209:etiology*
D003037:Cobalt Radioisotopes