title: Fatty acid acylated antibodies against virus suppress its reproduction in cells.
abstract: A method for suppression of virus reproduction in cells using fatty acylated antiviral antibodies, which in contrast to non-modified antibodies are capable of intracellular penetration, has been suggested. The addition of stearoylated antiviral antibodies to influenza A/Chili virus-infected cells causes a 100-fold suppression of virus reproduction. Non-modified antibodies do not produce any effect on virus reproduction.
authors.affiliation: Research Center of Molecular Diagnostics, USSR Ministry of Health, Moscow.
authors.forename: A V
authors.initials: AV
authors.lastname: Kabanov
authors.forename: A V
authors.initials: AV
authors.lastname: Ovcharenko
authors.forename: N S
authors.initials: NS
authors.lastname: Melik-Hubarov
authors.forename: A I
authors.initials: AI
authors.lastname: Bannikov
authors.lastname: Alakhov VYu
authors.forename: V I
authors.initials: VI
authors.lastname: Kiselev
authors.forename: P G
authors.initials: PG
authors.lastname: Sveshnikov
authors.forename: O I
authors.initials: OI
authors.lastname: Kiselev
authors.forename: A V
authors.initials: AV
authors.lastname: Levashov
authors.forename: E S
authors.initials: ES
authors.lastname: Severin
mesh_terms: D000215:Acylation; D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D005227:Fatty Acids; D009980:Influenza A virus / Q000276:immunology / Q000502:physiology*; D051379:Mice; D014779:Virus Replication
chemical_list: D000914:Antibodies, Viral; D005227:Fatty Acids