title: Peribulbar block for cataract surgery: a prospective double-blind study of two local anesthetics.
abstract: We carried out a prospective double-blind study to compare the effectiveness of 2% lidocaine hydrocarbonate (54 patients) and 2% lidocaine hydrochloride plus 0.5% bupivacaine hydrochloride (46 patients) in achieving peribulbar block of the orbit in patients undergoing cataract surgery. A total of 150 IU of hyaluronidase was added to each syringe before injection. Anesthesia was done with a total of 6 mL injected into the periphery of the orbit and a further 3 to 4 mL injected for seventh cranial nerve block. A successful block, defined as akinesis of the globe at 4 minutes after injection, was achieved in 94% of the patients, with no difference between the two groups. Two minor complications (transient lateral rectus paresis and a small retrobulbar hematoma) were observed. We recommend this method of peribulbar block as it has a rapid onset and its use may lead to a reduced occurrence of the central nervous system complications associated with retrobulbar block.
authors.affiliation: Department of Ophthalmology, Royal Victoria Hospital, Montreal.
authors.forename: P L
authors.initials: PL
authors.lastname: Davis
authors.forename: J P
authors.initials: JP
authors.lastname: O'Connor
mesh_terms: D000779:Anesthetics, Local; D002045:Bupivacaine / Q000493:pharmacokinetics*; D002387:Cataract Extraction; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D006801:Humans; D006821:Hyaluronoglucosaminidase / Q000008:administration & dosage; D008012:Lidocaine / Q000493:pharmacokinetics*; D009915:Orbit / Q000187:drug effects*; D011446:Prospective Studies; D013997:Time Factors
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine; D006821:Hyaluronoglucosaminidase; D002045:Bupivacaine