title: Genetic studies on nucleolus organizer regions (NORs) in cattle.
abstract: Experimentally produced monozygotic twins, natural opposite sex blood chimeras (freemartins), and several pedigrees were used to evaluate the genetic influences on the nucleolus organizer region (NOR) patterns in cattle. In monozygotic twins, the NOR patterns of both twins are extremely similar. In chimeras, NOR patterns of genetically identical, peripheral blood lymphocytes (PBL) from the two partners resemble each other. In contrast, genetically different PBL (sib organ) differ significantly in the same environment. A high heritability of the individual NOR patterns is also demonstrated in our 23 pedigrees. In conclusion, our data demonstrate that variation in NOR expression is predominantly due to genetic factors.
authors.forename: B
authors.initials: B
authors.lastname: Mayr
authors.forename: K
authors.initials: K
authors.lastname: Gruber
authors.forename: G
authors.initials: G
authors.lastname: Brem
authors.forename: G
authors.initials: G
authors.lastname: Mayrhofer
mesh_terms: D000818:Animals; D002417:Cattle / Q000235:genetics*; D002678:Chimera; D009697:Nucleolus Organizer Region / Q000648:ultrastructure*; D010375:Pedigree; D014427:Twins; D014430:Twins, Monozygotic