title: Application of thermal dilution measurements for thermal treatment planning.
abstract: The use of thermal dilution measurements is demonstrated in quantifying effective thermal conductivity distributions through tumours. For focused acoustic sources these data are applied in the solution of the heat diffusion equation to estimate steady-state temperature distributions. The advantages and disadvantages of this approach are presented. The effective conductivity measurements are found to be useful in predicting the circumstances under which this simple model can be applied and in aiding the selection of the most appropriate heating modality.
authors.affiliation: Department of Radiation Oncology, Cleveland Clinic Foundation, OH 44106.
authors.forename: P D
authors.initials: PD
authors.lastname: Higgins
authors.forename: C H
authors.initials: CH
authors.lastname: Sibata
authors.forename: F J
authors.initials: FJ
authors.lastname: Thomas
mesh_terms: D000818:Animals; D005260:Female; D005354:Fibrosarcoma / Q000628:therapy; D006979:Hyperthermia, Induced; D051379:Mice; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000628:therapy*; D012513:Sarcoma, Experimental / Q000628:therapy; D013814:Thermal Conductivity; D013815:Thermodilution