title: Results of a filtering procedure in low tension glaucoma.
abstract: Twenty-six eyes of twenty patients with established low tension glaucoma, who had either a 'double flap' Scheie filtering operation or a trabeculectomy, were followed over a period ranging from one to ten years, with a median of three years. These 26 eyes include two second eyes that served as a contralateral control eye until the visual field deteriorated. All 26 eyes showed progression of visual field defects preoperatively, while postoperatively only 2 eyes showed further progression. Of the 16 nonoperated contralateral eyes, 7 showed progression of visual field defects over the same follow-up period. Two of these 7 eyes had to be operated during the study-period. The difference in progression between the operated and the non-operated eyes was significant (P less than 0.01). The filtering procedure provided a reduction in IOP of 20% or more in 21 of 26 eyes. There was a significant difference in the mean intraocular pressure (IOP) between the operated and the non-operated contralateral eye of 6.8 mmHg (37%) at one year postoperatively. The diurnal variation decreased highly significantly from 4.3 to 2.1 mmHg (P less than 0.001). It is concluded that filtering surgery in low tension glaucoma may result not only in a significant lowering of IOP, but is also effective in slowing further deterioration of the visual fields.
authors.affiliation: The Netherlands Ophthalmic Research Institute, Amsterdam.
authors.forename: N
authors.initials: N
authors.lastname: de Jong
authors.forename: E L
authors.initials: EL
authors.lastname: Greve
authors.forename: P F
authors.initials: PF
authors.lastname: Hoyng
authors.forename: H C
authors.initials: HC
authors.lastname: Geijssen
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013997:Time Factors; D014130:Trabeculectomy; D014792:Visual Acuity; D058609:Visual Field Tests; D014794:Visual Fields