title: [Functional consequences and complications of Paget's disease].
abstract: Paget's disease is a common bone disease which usually has little influence on the patient's mobility. Functional symptoms, such as pain, and bone deformation can be controlled partly by treatment. Cardiovascular complications are rare, except for arterial hypertension which seems to be closely related to the skeletal dystrophy. The incidence of sarcoma is difficult to evaluate, but that disease has a frightful prognosis little improved by therapeutics. Neurological manifestations are diverse and due to anatomical alterations and vascular steal syndromes. Bone fractures are frequent and sometimes herald the disease. Pagetic arthropathies may benefit from surgery after medical treatment.
authors.forename: J M
authors.initials: JM
authors.lastname: Farre
authors.forename: B
authors.initials: B
authors.lastname: Delcambre
mesh_terms: D000368:Aged; D001859:Bone Neoplasms / Q000209:etiology; D002318:Cardiovascular Diseases / Q000209:etiology; D005260:Female; D005598:Fractures, Spontaneous / Q000209:etiology; D006801:Humans; D007592:Joint Diseases / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000209:etiology; D010001:Osteitis Deformans / Q000150:complications* / Q000503:physiopathology; D012516:Osteosarcoma / Q000209:etiology
vernacular_title: Conséquences fonctionnelles et complications de la maladie de Paget.