[Spontaneous arteriovenous shunt in chronic arterial occlusive disease of the lower extremities. A nuclear medicine study].
For radionuclide assessment of AV-shunting Tc99m aggregated albumin microspheres were injected into the proximal femoral artery in 10 patients with chronic peripheral OAD and a visualized proximal AV shunt during percutaneous transluminal angioplasty. Isotope activity in the lungs and the afflicted leg was investigated with a computer-linked whole body scanner. 12 patients undergoing the same treatment but without proximal AV shunt and one healthy volunteer served as control group. In this group 6 patients suffered from longtime diabetes. Patients with visualized AV shunts showed a significant higher isotope activity in the lungs than non-diabetics without proximal shunts. To our surprise diabetics without proximal AV fistula proved to have also a significant augmented pulmonary activity. Pathophysiological conditions for the evolution of proximal and peripheral AV shunts in patients with chronic OAD are discussed. The poor response to local clot lyses in patients with radionuclide prove of AV shunts underlines their hemodynamic importance under clinical aspects.
Stein
U
U
Börner
C
C
Wagner
E
E
D000368:Aged; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging*; D001164:Arteriovenous Fistula / Q000000981:diagnostic imaging*; D003925:Diabetic Angiopathies / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008297:Male; D011651:Pulmonary Artery / Q000000981:diagnostic imaging; D011667:Pulmonary Veins / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D012422:Rupture, Spontaneous; D013668:Technetium Tc 99m Aggregated Albumin
D013668:Technetium Tc 99m Aggregated Albumin
Spontane AV-Shunts bei chronischer AVK der unteren Extremitäten. Eine nuklearmedizinische Studie.