title: Salivary lactoferrin in primary Sjögren's syndrome.
abstract: Parotid salivary lactoferrin (LF) levels were measured in 26 patients with Sjögren's syndrome (SS), 19 patients with keratoconjunctivitis sicca (KCS) and 32 normal controls, by using a radial-immunodiffusion technique. The levels of LF were higher in SS than in KCS patients (23 +/- 21, 10 +/- 10, p less than 0.03) and in SS patients than in normals (7 +/- 6 micrograms/ml, p less than 0.001). There was some relationship of the LF level to the labial salivary gland histopathology grade.
authors.affiliation: Department of Immunology, Brest University Medical School, France.
authors.forename: N
authors.initials: N
authors.lastname: Jezequel
authors.forename: F
authors.initials: F
authors.lastname: Depasse
authors.forename: J
authors.initials: J
authors.lastname: Jouquan
authors.forename: A
authors.initials: A
authors.lastname: Lelong
authors.forename: S
authors.initials: S
authors.lastname: Roncin
authors.forename: G
authors.initials: G
authors.lastname: Pare
authors.forename: Y L
authors.initials: YL
authors.lastname: Pennec
authors.forename: P
authors.initials: P
authors.lastname: Youinou
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007638:Keratoconjunctivitis Sicca / Q000378:metabolism; D007781:Lactoferrin / Q000378:metabolism*; D007782:Lactoglobulins / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D010306:Parotid Gland / Q000378:metabolism*; D012463:Saliva / Q000378:metabolism*; D012859:Sjogren's Syndrome / Q000175:diagnosis* / Q000378:metabolism; D014987:Xerostomia / Q000175:diagnosis* / Q000378:metabolism
chemical_list: D007782:Lactoglobulins; D007781:Lactoferrin