[The phospholipid spectrum of the blood serum in patients with chronic non-specific pulmonary diseases during rehabilitation treatment].
Lipid metabolism was studied in 49 patients with chronic non-specific pulmonary diseases. The judgement about lipid metabolism was formed on the basis of changes in the content of phospholipid (PL) fractions in the patients' blood serum under the influence of health resort treatment. PL were separated by micro-thin-layer chromatography. They included five fractions: phosphatidylcholine (PC), sphingomyelin (SM), lysophosphatidylcholine (LPC), phosphatidylethanolamine (PE) and phosphatidylinositol (PI). The patients with chronic non-specific pulmonary diseases showed a significant decrease in the PC level and a rise of SM, LPC and PI. In the course of health resort treatment, lipid metabolism in the patients did not return to normal. The tendency towards normalization was observed only by the sixth month after rehabilitation treatment. The changes discovered are of diagnostic importance and can be used in the assessment of the efficacy of health resort treatment aimed at the removal of the inflammatory process in the lungs.
Ivanov
E M
EM
Novgorodtseva
T P
TP
Endakova
E A
EA
Svetashev
V I
VI
D000328:Adult; D002908:Chronic Disease; D005260:Female; D006294:Health Resorts; D006801:Humans; D008171:Lung Diseases / Q000097:blood* / Q000628:therapy; D008244:Lysophosphatidylcholines / Q000097:blood; D008297:Male; D008875:Middle Aged; D010713:Phosphatidylcholines / Q000097:blood; D010714:Phosphatidylethanolamines / Q000097:blood; D010716:Phosphatidylinositols / Q000097:blood; D010743:Phospholipids / Q000097:blood*; D013109:Sphingomyelins / Q000097:blood
D008244:Lysophosphatidylcholines; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D010716:Phosphatidylinositols; D010743:Phospholipids; D013109:Sphingomyelins
Fosfolipidnyĭ spektr syvorotki krovi bol'nykh khronicheskimi nespetsificheskimi zabolevaniiami legkikh v protsesse vosstanovitel'nogo lecheniia.