title: The effect of different dosages of a transdermal nicotine substitution system on the success rate of smoking cessation therapy.
abstract: The effectiveness of different nicotine dosages on abstinence rates was investigated in a smoking cessation study. One hundred smokers underwent nine weeks of self-controlled treatment based on behavioral principles. The overall group was divided into two subgroups randomized according to sex, cigarette consumption and age. The first group (n = 51) was given a nicotine dose adapted to daily cigarette consumption. The second group (n = 49) was given a standardized dose. There was, unexpectedly, no difference between the two groups in respect to short-term abstinence rates. These results suggest that standardized dosage is preferred to individually adapted dosage.
authors.affiliation: Clinic for Psychiatry, University of Münster, FRG.
authors.forename: E
authors.initials: E
authors.lastname: Minneker
authors.forename: G
authors.initials: G
authors.lastname: Buchkremer
authors.forename: M
authors.initials: M
authors.lastname: Block
mesh_terms: D000279:Administration, Cutaneous; D001521:Behavior Therapy; D003131:Combined Modality Therapy; D006801:Humans; D009538:Nicotine / Q000008:administration & dosage / Q000627:therapeutic use*; D012907:Smoking / Q000188:drug therapy / Q000523:psychology / Q000628:therapy*; D013375:Substance Withdrawal Syndrome / Q000523:psychology; D013997:Time Factors
chemical_list: D009538:Nicotine