title: A comparison of two RAST methods and skin prick testing in the diagnosis of wasp venom allergy.
abstract: With the aim of evaluating the correlation between skin prick test and two radioallergosorbent tests (RAST) using paper (P-RAST) and Al(OH)3 (Al-RAST) as sorbent materials, 45 consecutive patients known to have been stung by wasp within 6 months were examined. Four patients had a normal reaction, four a large local reaction and 37 a systemic reaction. We found a good correlation between a systemic reaction and a positive P-RAST. Fifty-one per cent of patients with a systemic reaction had a negative Al-RAST, whereas only 8% had a negative P-RAST. Eight per cent of patients with a systemic reaction had a negative SPT. In the eight patients without a systemic reaction, the same patient reacted positively in Al-RAST and P-RAST.
authors.affiliation: Medical Department TTA, State University, Hospital, Copenhagen, Denmark.
authors.forename: J H
authors.initials: JH
authors.lastname: Heinig
authors.forename: H
authors.initials: H
authors.lastname: Mosbech
authors.forename: T
authors.initials: T
authors.lastname: Engel
authors.forename: L
authors.initials: L
authors.lastname: Frølund
authors.forename: U G
authors.initials: UG
authors.lastname: Svendsen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000937:Antigen-Antibody Reactions; D001514:Bee Venoms / Q000008:administration & dosage / Q000276:immunology*; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis*; D008875:Middle Aged; D011446:Prospective Studies; D011852:Radioallergosorbent Test / Q000379:methods; D012882:Skin Tests / Q000379:methods
chemical_list: D001514:Bee Venoms