[Ex vivo study of the effect of ribomunyl on the release of oxygen radicals by polynuclear neutrophils].
The ex vivo study of the chemiluminescence index of polynuclear neutrophils before and after treatment of 6 children who were receiving injectable Ribomunyl for ORL infections showed an increase of more than 600% of the mean value of the index after treatment. Ribomunyl therefore potentiates the bactericidal activity of polynuclear neutrophils.
Rahimy
M C
MC
Service de Pédiatrie, CHI, Créteil.
Bernaudin
F
F
Doppelt
E
E
de la Rocque
F
F
Plan
D
D
Reinert
P H
PH
Bernaudin
J F
JF
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000942:Antigens, Bacterial / Q000494:pharmacology*; D001424:Bacterial Infections / Q000628:therapy*; D005609:Free Radicals; D006801:Humans; D007167:Immunotherapy; D009504:Neutrophils / Q000187:drug effects*; D010038:Otorhinolaryngologic Diseases / Q000628:therapy*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000097:blood; D012270:Ribosomes
D000276:Adjuvants, Immunologic; D000942:Antigens, Bacterial; D005609:Free Radicals; C034206:Ribomunyl; D010100:Oxygen
Etude ex vivo de l'effet du ribomunyl sur le relargage des radicaux oxydants par les polynucléaires neutrophiles.