title: Inflammatory aneurysms of the abdominal aorta: incidence, pathologic, and etiologic considerations.
abstract: Among 486 patients undergoing repair for abdominal aortic aneurysm (AAA) during a 12-year period, 30 (6.2%) had evidence of "inflammatory" AAA. One patient (3%) had acute rupture, and six patients (20%) had chronic contained rupture. Ureteral obstruction was evident in 20% of the patients. In the early period of the study there were two postoperative deaths and operative time and blood loss were significantly increased. In the last period of the study, no attempt was made to separate the duodenum and the ureters from the aneurysm; there was no operative mortality, and operative time and blood loss were similar to that of patients with atherosclerotic aneurysms. In 23 of 100 specimens of atherosclerotic AAA, microscopic findings resembling inflammatory AAA were found. On the basis of our study we conclude the following: (1) Inflammatory AAAs are simply atherosclerotic aneurysms that show an unusual accentuation of the chronic inflammation observed in relation to atherosclerotic aneurysms. (2) Operative technique should be modified to avoid excessive dissection and lysis of ureters and duodenum. (3) Excellent early and late results can be expected with proper surgical technique. (4) The causes of AAA are multiple, and chronic contained rupture of the aneurysm and reactive lymphatic hyperplasia might play a role of greater significance than previously thought.
authors.affiliation: Department of Surgery, Creighton University School of Medicine, Omaha, NE 68131.
authors.forename: A V
authors.initials: AV
authors.lastname: Sterpetti
authors.forename: W J
authors.initials: WJ
authors.lastname: Hunter
authors.forename: R J
authors.initials: RJ
authors.lastname: Feldhaus
authors.forename: P
authors.initials: P
authors.lastname: Chasan
authors.forename: M
authors.initials: M
authors.lastname: McNamara
authors.forename: S
authors.initials: S
authors.lastname: Cisternino
authors.forename: R D
authors.initials: RD
authors.lastname: Schultz
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001012:Aorta, Abdominal / Q000473:pathology / Q000601:surgery; D001014:Aortic Aneurysm / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology / Q000601:surgery; D001019:Aortic Rupture / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000473:pathology / Q000601:surgery; D001025:Aortitis / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology / Q000601:surgery; D001161:Arteriosclerosis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors