title: The gene for human complement component C9 mapped to chromosome 5 by polymerase chain reaction.
abstract: The gene for human complement component C9 has been mapped to chromosome 5. This was achieved by using a novel application of the polymerase chain reaction to amplify specifically the human C9 gene on a background of rodent DNA in somatic cell hybrids. The assignment to chromosome 5 was confirmed by in situ hybridization to human metaphase chromosomes, giving a regional localization of 5p13.
authors.affiliation: MRC Human Biochemical Genetics Unit, Galton Laboratory, University College London, United Kingdom.
authors.forename: C
authors.initials: C
authors.lastname: Abbott
authors.forename: L
authors.initials: L
authors.lastname: West
authors.forename: S
authors.initials: S
authors.lastname: Povey
authors.forename: S
authors.initials: S
authors.lastname: Jeremiah
authors.forename: Z
authors.initials: Z
authors.lastname: Murad
authors.forename: R
authors.initials: R
authors.lastname: DiScipio
authors.forename: G
authors.initials: G
authors.lastname: Fey
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D002895:Chromosomes, Human, Pair 5; D003186:Complement C9 / Q000235:genetics*; D006224:Cricetinae; D003412:Cricetulus; D005784:Gene Amplification; D005796:Genes; D006801:Humans; D006822:Hybrid Cells; D051379:Mice; D051381:Rats
chemical_list: D003186:Complement C9