[Effect of BCG and cyclophosphamide on the antitumor activity of mouse peritoneal macrophages].
Peritoneal macrophages activated by BCG and cyclophosphamide were unable to complete elimination of small numbers of tumour cells in spite of high level of cytotoxicity and cytostatic activity of these cells. It is appeared useful to evaluate the influence of new immunomodulators and combinations of immunomodulators with chemotherapeutic drugs not only on the cytotoxic and cytostatic, but also on the "feeder" activity of macrophages.
Gromov
S A
SA
Okulov
V B
VB
Voĭtenkov
B O
BO
D000818:Animals; D001500:BCG Vaccine / Q000494:pharmacology*; D003520:Cyclophosphamide / Q000494:pharmacology*; D003602:Cytotoxicity, Immunologic / Q000187:drug effects; D006825:Hybridomas / Q000187:drug effects / Q000276:immunology; D008262:Macrophage Activation / Q000187:drug effects; D008264:Macrophages / Q000187:drug effects* / Q000276:immunology; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D009101:Multiple Myeloma / Q000276:immunology*; D010529:Peritoneal Cavity / Q000166:cytology; D013997:Time Factors
D001500:BCG Vaccine; D003520:Cyclophosphamide
Vliianie BTsZh i tsiklofosfamida na protivoopukholevuiu aktivnost' peritoneal'nykh makrofagov mysheĭ.