title: Retrospective study of early postoperative convulsions after intracranial surgery with isoflurane or enflurane anaesthesia.
abstract: Retrospective analysis of the case records of 383 patients undergoing elective intracranial surgery showed that, in the first 24 h after surgery, 13.9% of patients receiving low concentrations (0.4-1 MAC) of isoflurane had one or more convulsions after operation, compared with 8% receiving enflurane (0.4-1 MAC). Controlled ventilation was required as part of the therapy for convulsions in 4.9% of the isoflurane group and 3.6% of the enflurane group. These differences between the groups were not statistically significant.
authors.affiliation: General Infirmary, Leeds.
authors.forename: A R
authors.initials: AR
authors.lastname: Christys
authors.forename: E
authors.initials: E
authors.lastname: Moss
authors.forename: D
authors.initials: D
authors.lastname: Powell
mesh_terms: D000769:Anesthesia, Inhalation / Q000009:adverse effects; D001921:Brain / Q000601:surgery*; D004737:Enflurane / Q000009:adverse effects; D006801:Humans; D007530:Isoflurane / Q000009:adverse effects; D011183:Postoperative Complications / Q000628:therapy; D012121:Respiration, Artificial; D012189:Retrospective Studies; D012640:Seizures / Q000209:etiology* / Q000628:therapy
chemical_list: D004737:Enflurane; D007530:Isoflurane