[Relation of bacitracin synthesis and manganese content in Bacillus licheniformis: antibiotic production in colonies forming on media with high levels of Mn2+].
Population of B. licheniformis is not homogeneous with respect to its sensitivity to Mn2+. Active bacitracin producing cultures with high and low sensitivity to exogenic manganese are described. In media containing high sublethal concentrations of Mn2+ there were detected two types of bacitracin-producing colonies i.e. light and dark differing likely in the mechanisms of their cell protection from the metal excess. Since bacitracin production did not always correlate with sensitivity to Mn2+ at the level of the colony formation the use of Mn2+ as a selective factor for isolating inactive strains of B. licheniformis is of low efficiency.
Kuzovnikova
T A
TA
Zhdanov
V G
VG
D001407:Bacillus / Q000378:metabolism*; D001414:Bacitracin / Q000096:biosynthesis*; D003470:Culture Media; D008345:Manganese / Q000032:analysis*
D003470:Culture Media; D001414:Bacitracin; D008345:Manganese
Vzaimozavisimost' mezhdu sintezom batsitratsina i soderzhaniem margantsa u Bacillus licheniformis: Antibiotikoobrazovanie u koloniĭ, sformirovannykh na srede s vysokim urovnem Mn2+.