title: Aspirin abolishes tinnitus caused by spontaneous otoacoustic emissions. A case study.
abstract: A series of experimental tests are presented indicating that numerous spontaneous otoacoustic emissions (SOAEs) are likely to provide the basis of monaural tinnitus for one female patient. For this patient, (1) the tinnitus disappeared only when all SOAE components were suppressed, (2) with all but one emission suppressed, the frequency of an external tone said to match the pitch of the tinnitus was close to the frequency of the unsuppressed SOAE, and (3) the isomasking contour for the tinnitus was frequency specific. All these tests indicated that the patient was likely to be hearing SOAEs. During subsequent aspirin administration, her SOAEs disappeared and her perception of her tinnitus was radically altered. The tinnitus was no longer described as monaural and "tonal" but instead was described as being "noise in the head."
authors.affiliation: Department of Psychology, University of Maryland, College Park 20742.
authors.forename: M J
authors.initials: MJ
authors.lastname: Penner
mesh_terms: D001241:Aspirin / Q000627:therapeutic use*; D003051:Cochlea / Q000502:physiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010470:Perceptual Masking; D014012:Tinnitus / Q000188:drug therapy* / Q000209:etiology
chemical_list: D001241:Aspirin