[Estimation of parental resistance in evaluating the effect of chemical substances on children's health].
Proceeding from the experimental study carried out on the model of aniline methemoglobinemia, it was shown that the animals with low aniline-related resistance also had aniline low-resistant posterity during two following generations and vice versa high-resistant animals had the more aniline-resistant posterity. It was determined both by methemoglobin levels and by the number of animals with different methemoglobin levels. According to the degree of aniline-induced methemoglobinemia the correlation among three generations of animals was established.
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D000814:Aniline Compounds / Q000633:toxicity*; D000818:Animals; D004195:Disease Models, Animal; D004342:Drug Hypersensitivity / Q000235:genetics*; D004351:Drug Resistance; D005260:Female; D008297:Male; D008708:Methemoglobinemia / Q000139:chemically induced* / Q000235:genetics; D010290:Parents; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats
D000814:Aniline Compounds
Ob uchete rezistentnosti organizma roditeleĭ pri otsenke vliianiia khimicheskikh veshchestv na zdorov'e deteĭ.