[An experimental model of DIC syndrome].
Disseminated intravascular coagulation syndrome (DIC-syndrome) is experimentally reproduced by introduction of 30% aqueous solution "Desoxon-3" (2800-300 mg/kg) into the organism of laboratory animals (rabbits). The preparation was perorally introduced once on an empty stomach for 1 min. Biochemical and pathomorphological studies testify to the development of the typical DIC-syndrome in rabbits. It is concluded that the model suggested makes it possible to thoroughly study genesis, course, consequences of the development and preventive measures of disseminated intravascular blood coagulation, a complex pathological process.
Shchepotin
B M
BM
Ena
Ia M
IaM
Dibrova
V A
VA
Shevchenko
E A
EA
Vinogradova
G N
GN
D000818:Animals; D004195:Disease Models, Animal; D004211:Disseminated Intravascular Coagulation / Q000473:pathology*; D008833:Microcirculation / Q000473:pathology; D011817:Rabbits; D013927:Thrombosis / Q000473:pathology*; D014781:Viscera / Q000098:blood supply*
Eksperimental'naoa model' DVS-sindroma.