title: Case report: idiopathic giant cell granuloma of the hypophysis: an unusual cause of panhypopituitarism.
abstract: A 37-year-old man presented with headache and reduced libido. He suffered from panhypopituitarism, and the walls of the pituitary fossa were noted to be thickened, sclerotic, and irregular. Computed tomography scans showed an intrasellar and suprasellar, patchy enhancing tumor. From a biopsy taken at transsphenoidal surgery, a giant cell granuloma was diagnosed, for which there was no obvious cause. Inflammatory disease within the pituitary fossa should be suspected if a reaction is seen in the surrounding bone.
authors.affiliation: Department of Neurosciences, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
authors.forename: E
authors.initials: E
authors.lastname: Siqueira
authors.forename: J S
authors.initials: JS
authors.lastname: Tsung
authors.forename: M Z
authors.initials: MZ
authors.lastname: Al-Kawi
authors.forename: N
authors.initials: N
authors.lastname: Woodhouse
mesh_terms: D000328:Adult; D006101:Granuloma, Giant Cell / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology*; D008297:Male; D010900:Pituitary Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed