[Compounds similar to acyclovir. IV. A convenient method of synthesizing adenallene].
A convenient method for the synthesis of adenallen (9-(4-hydroxy-1,2-butadienil)adenine) is proposed. Adenallen was prepared in 30% yield by alkaline treatment of 9-(4-acetoxy-2-butinyl)adenine synthesized, in turn, by condensation of sodium derivative of adenine with 4-acetoxy-1-chlorbutine-2.
Khorlin
A A
AA
Smirnov
I P
IP
Kochetkova
S V
SV
Tsilevich
T L
TL
Shchaveleva
I L
IL
D000212:Acyclovir / Q000031:analogs & derivatives*; D000225:Adenine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D055598:Chemical Phenomena; D002621:Chemistry; D009682:Magnetic Resonance Spectroscopy; D009705:Nucleosides / Q000032:analysis; D013056:Spectrophotometry, Ultraviolet
D009705:Nucleosides; C056909:adenallene; D000225:Adenine; D000212:Acyclovir
Soedineniia, podobnye atsikloviru. IV. Udobnyĭ metod sinteza adenallena.