title: Meningiomas: karyotypes and histological patterns.
abstract: The cytogenetic findings, based on G-banding, in six meningiomas are reported. Normal karyotypes were found in three cases and monosomy of chromosome 22 in the remaining three. In one of these three cases, a malignant meningioma, several chromosomes were lost, gonosome Y included. The possible significance of the association of chromosome alterations in meningiomas with the histology of the tumor and its biological aggressivity is discussed.
authors.affiliation: Department of Pathology, University Hospital Valencia, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Lopez-Gines
authors.forename: J
authors.initials: J
authors.lastname: Piquer
authors.forename: M
authors.initials: M
authors.lastname: Cerda-Nicolas
authors.forename: J
authors.initials: J
authors.lastname: Barcia-Salorio
authors.forename: C
authors.initials: C
authors.lastname: Barcia-Marino
mesh_terms: D000328:Adult; D002869:Chromosome Aberrations / Q000473:pathology*; D025063:Chromosome Disorders; D002892:Chromosomes, Human, Pair 22; D006801:Humans; D007621:Karyotyping; D008297:Male; D008577:Meningeal Neoplasms / Q000235:genetics* / Q000473:pathology; D008579:Meningioma / Q000235:genetics* / Q000473:pathology; D008875:Middle Aged