title: [The hypotensive action of anaprilin in hypertension].
abstract: A study of the central hemodynamics in the course of treatment with anaprilin of 137 hypertensive patients with different clinico-pathogenetic variants and types of blood circulation indicates that the hemodynamic basis of hypotensive effect of the drug in patients with the hyperdynamic type is a reduction of the cardiac output and normalization of the changed general peripheral vascular resistance (GPVR) while patients with the hypodynamic type showed a distinct GPVR reduction and an increase of the cardiac output values. A hypotensive effect of anaprilin was noted in 82.5%.
authors.forename: E V
authors.initials: EV
authors.lastname: Andrushchenko
authors.forename: I N
authors.initials: IN
authors.lastname: Rubaĭ
mesh_terms: D000293:Adolescent; D000328:Adult; D001919:Bradycardia / Q000188:drug therapy / Q000503:physiopathology; D004341:Drug Evaluation; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011433:Propranolol / Q000627:therapeutic use*; D013610:Tachycardia / Q000188:drug therapy / Q000503:physiopathology
chemical_list: D011433:Propranolol
vernacular_title: O gipotenzivnom deĭstvii anaprilina pri gipertonicheskoĭ bolezni