Prevention of chronic ITP?
The treatment of childhood ITP with IVIG has been widely used in acute or in previously treatment-dependent, chronic forms of the disease. We discuss propositions of a prospective multicenter study to evaluate the efficacy of IVIG to prevent the development of chronic ITP in childhood. The problems of such a study, i.e. evaluation criteria, number (about 10% of patients with acute ITP will develop the chronic form) and related topics are discussed.
Müller
B U
BU
Department of Pediatrics, University Hospitals, Berne, Switzerland.
Imbach
P
P
D002648:Child; D002908:Chronic Disease; D006801:Humans; D007116:Immunization, Passive; D010976:Platelet Count; D011696:Purpura, Thrombocytopenic / Q000517:prevention & control*