[Changes in the morphology of fibroblasts of different degrees of transformation under the action of 12-tetradecanoylphorbol-13-acetate].
A study was made of morphological changes in mouse sarcoma cells of two clones, as well as in BALB/c 3T3 mouse fibroblasts and in mouse embryonal fibroblasts, upon the action of the promotor 12-O-tetradecanoylphorbol-13-acetate (TPA). In all the cell types, with the exception of mouse embryo fibroblasts, TPA induced specific changes in the shape and cytoskeleton, the most obvious changes being observed in cells with higher malignant characteristics.
Dugina
V B
VB
D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000187:drug effects* / Q000473:pathology; D002478:Cells, Cultured; D004622:Embryo, Mammalian; D005347:Fibroblasts / Q000166:cytology / Q000187:drug effects*; D051379:Mice; D008807:Mice, Inbred BALB C; D008808:Mice, Inbred CBA; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
D013755:Tetradecanoylphorbol Acetate
Izmeneniia morfologii fibroblastov razlichnoĭ stepeni transformatsii pri deĭstvii 12-tetradekanoilforbol-13-atsetata.