Treatment of persistent penile erection and priapism using terbutaline.
The recent finding of terbutaline as the treatment of choice to manage intraoperative penile tumescence with the patient under anesthesia (general and regional) has prompted us to use this beta-2 agonist (5 mg. orally) for persistent penile erection and priapism resulting from injection of pharmacological agents, such as phentolamine, phenoxybenzamine and papavarine, into the penis for erectile impotence. The drug also has been used successfully (0.25 to 0.5 mg. intravenously or subcutaneously) to treat priapism developing despite a cavernosum-spongiosum shunt procedure. This and other pure beta 2 agonists will have an important role in the treatment of undesirable and painful penile erection, alone or in association with other invasive and noninvasive intervention.
Shantha
T R
TR
Department of Anesthesiology, Georgia Baptist Medical Center, Atlanta 30312.
Finnerty
D P
DP
Rodriquez
A P
AP
D000328:Adult; D000368:Aged; D007172:Erectile Dysfunction / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010208:Papaverine / Q000627:therapeutic use; D010410:Penile Erection / Q000187:drug effects*; D010643:Phenoxybenzamine / Q000627:therapeutic use; D010646:Phentolamine / Q000627:therapeutic use; D011317:Priapism / Q000139:chemically induced / Q000188:drug therapy*; D012646:Self Administration; D013726:Terbutaline / Q000627:therapeutic use*; D013997:Time Factors
D010643:Phenoxybenzamine; D010208:Papaverine; D013726:Terbutaline; D010646:Phentolamine