Meningiomas: karyotypes and histological patterns.
The cytogenetic findings, based on G-banding, in six meningiomas are reported. Normal karyotypes were found in three cases and monosomy of chromosome 22 in the remaining three. In one of these three cases, a malignant meningioma, several chromosomes were lost, gonosome Y included. The possible significance of the association of chromosome alterations in meningiomas with the histology of the tumor and its biological aggressivity is discussed.
Lopez-Gines
C
C
Department of Pathology, University Hospital Valencia, Spain.
Piquer
J
J
Cerda-Nicolas
M
M
Barcia-Salorio
J
J
Barcia-Marino
C
C
D000328:Adult; D002869:Chromosome Aberrations / Q000473:pathology*; D025063:Chromosome Disorders; D002892:Chromosomes, Human, Pair 22; D006801:Humans; D007621:Karyotyping; D008297:Male; D008577:Meningeal Neoplasms / Q000235:genetics* / Q000473:pathology; D008579:Meningioma / Q000235:genetics* / Q000473:pathology; D008875:Middle Aged