Rates of de novo fatty acid synthesis in liver, muscle and adipose tissue in non-pregnant and pregnant rats in vivo.
Fatty acid de novo synthesis was measured quantitatively in liver, muscle and adipose tissue of non-pregnant and 21-day pregnant Uje: WIST rats in vivo. By means of 3H2O incorporation experiments the following rates of fatty acid synthesis, expressed as mumol palmitate-equivalents/animal.min, were calculated in non-pregnant and pregnant animals: liver 0.20 +/- 0.06 and 0.24 +/- 0.06; muscle 0.21 +/- 0.06 and 0.24 +/- 0.08; adipose tissue, 0.36 +/- 0.10 and 0.28 +/- 0.09, respectively. Thus, liver, muscle and adipose tissue contribute at approximately equal amounts to the summarized rate of fatty acid synthesis, which is similar in both pregnant and non-pregnant rats.
Zimmermann
T
T
Institute of Pathological Biochemistry, Friedrich Schiller University, Jena, GDR.
Hummel
L
L
Dargel
R
R
D000273:Adipose Tissue / Q000378:metabolism*; D000818:Animals; D005227:Fatty Acids / Q000096:biosynthesis*; D005260:Female; D008099:Liver / Q000378:metabolism*; D009132:Muscles / Q000378:metabolism*; D009928:Organ Specificity; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values; D014316:Tritium
D005227:Fatty Acids; D014316:Tritium