Antidepressant response in chronic major depression.
Treatment response to antidepressant medication was examined in 59 patients with nonchronic major depression and 35 patients with chronic major depression. Patients with chronic major depression had a poorer response to imipramine or desipramine than nonchronic patients.
Garvey
M J
MJ
Department of Psychiatry, Veterans Administration Medical Center, Iowa City, IA 52240.
Cook
B L
BL
Tollefson
G D
GD
Schaffer
C B
CB
D000328:Adult; D000928:Antidepressive Agents / Q000627:therapeutic use*; D002908:Chronic Disease; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D003891:Desipramine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011581:Psychological Tests
D000928:Antidepressive Agents; D007099:Imipramine; D003891:Desipramine