[Reversible deep whole-body hypothermia in rats].
The effect of deep hypothermia on the rat's organism was investigated without the use of hypercapnic hypoxia or administration of medicine. The possibility of resuscitation and rehabilitation of rats after deep hypothermia depending on different rate of heating have been also studied. It has been observed that the cardiac activity stopped at about 3 degrees C. We supposed that the extremely intensive heating and temperature rise of an organism were both limiting factors. We have discovered that the low intensity of heating was the next factor of limitation which was connected with the duration of clinical death. These experiments showed that the intensive cooling and heating (about 0.4 degrees C per min.) are the best for resuscitation and rehabilitation after deep hypothermia.
Shcherbakov
P V
PV
Tel'pukhov
V I
VI
Khokhlov
A V
AV
D000818:Animals; D001831:Body Temperature; D007035:Hypothermia / Q000401:mortality / Q000503:physiopathology* / Q000628:therapy; D007036:Hypothermia, Induced / Q000379:methods; D008297:Male; D009200:Myocardial Contraction; D051381:Rats; D011919:Rats, Inbred Strains; D012007:Rectum; D012151:Resuscitation / Q000379:methods; D013997:Time Factors
Obratimaia glubokaia gipotermiia tselostnogo organizma krys.