[Changes in the efferent impulsation in the vagus nerves during the metastasis of Lewis lung carcinoma in mice].
In electrophysiological experiments the reflectory reaction of the efferent impulsation in the vagus nerve elicited by the stimulation of the lung and airway receptors was studied in the mice with the lung Lewis carcinoma. It has been established that the extension of the metastatic process was accompanied by the disturbances in the relationships of the central cholin- and dopaminergic mechanisms of the respiratory nervous regulation with hyperactivation of the former and depression of the latter. The use of the neurotropic drugs of the central action normalizing or disturbing these interrelations inhibits or stimulates, respectively, the metastatic process.
Syromiatnikov
A V
AV
Alistratov
A V
AV
D000818:Animals; D002491:Central Nervous System Agents / Q000494:pharmacology; D004525:Efferent Pathways / Q000187:drug effects / Q000503:physiopathology; D008175:Lung Neoplasms / Q000503:physiopathology / Q000556:secondary*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009368:Neoplasm Transplantation; D012018:Reflex / Q000187:drug effects / Q000502:physiology; D012119:Respiration / Q000187:drug effects; D014630:Vagus Nerve / Q000187:drug effects / Q000503:physiopathology*
D002491:Central Nervous System Agents
Izmenenie éfferentnoĭ impul'satsii v bluzhdaiushchikh nervakh pri metastazirovanii kartsinomy legkikh L'iuis u mysheĭ.