[Low- and high-threshold calcium current in the membrane of cultured neurons of Helix pomatia].
Two components of the inward calcium current were observed in the membrane of cultured Helix pomatia neurons by the patch clamp method in its whole cell configuration. The first one was activated at high-negative membrane potentials (-70- -60 mV), had low amplitude (200 pA at 15 mmol/l of Ca2+ ions as a charge carrier) and displayed time-dependent inactivation. A second, larger current component (2 nA, the same conditions) appeared at more positive potentials (-20 mV). Its time-dependent inactivation was much less expressed. The tail currents of the low amplitude component were slower than those associated with the high-amplitude component.
Lozinskaia
I M
IM
Shuba
Ia M
IaM
D000818:Animals; D002118:Calcium / Q000502:physiology*; D002478:Cells, Cultured; D006372:Helix, Snails / Q000502:physiology*; D008564:Membrane Potentials; D009474:Neurons / Q000502:physiology*
D002118:Calcium
Nizko- i vysokoporogovyĭ kal'tsievyĭ tok v membrane kul'tivirovannykh neĭronov vinogradnoĭ ulitki.