[Observation on platelet aggregation in retinal vein occlusion].
The authors studied the maximum platelet aggregation curve (PAgT max%) in 25 patients of retinal vein occlusion (RVO) before treatment with TCM and compared with 30 normal adults as controls. The results of PAgT max% induced by 1.0 microgram/ml adrenaline were 67.44 +/- 20.91 in 25 patients of RVO, and 54.30 +/- 12.66 in normal adults, when induced by 0.6 mumol ADP there were 65, 68 +/- 11.25 and 45.37 +/- 14.57 respectively. It showed higher than normal value in 20 out of 25 patients of RVO. The results indicated that there was a significant correlation with the RVO and raising of PAgT max% (P less than 0.01-0.001), but there was no significant difference between male and female groups (P greater than 0.05). After treatment with TCM, 14 out of the 20 abnormal PAgT max% cases were examined, the results of PAgT max% induced by 1.0 microgram/ml adrenaline reduced from 70.50 +/- 7.32 before treatment to 50.93 +/- 19.40 after treatment, and by 0.6 microgram mol ADP reduced from 70.86 +/- 8.85 before treatment to 46.21 +/- 10.88 after treatment. The treatment with TCM seemed to convert the high PAgT max% to normal value and also improved the symptoms and signs.
Deng
Z H
ZH
D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects*; D012170:Retinal Vein Occlusion / Q000097:blood* / Q000188:drug therapy
D004365:Drugs, Chinese Herbal