Absence of a hemispheric difference in seizure sensitivity and kindling rate in the rat brain.
The question of a population hemispheric asymmetery in initial seizure sensitivity and in rate of kindling in the amygdala was examined in an unbiased sample of 80 rats studied in our laboratory during the past six years. Afterdischarge threshold, initial and final afterdischarge duration, and kindling rate were the same in rats kindled in the left or right basolateral amygdala. The results suggest that there is no systematic difference between the hemispheres in initial seizure sensitivity or rate of amygdala kindling.
Cain
D P
DP
Department of Psychology, University of Western Ontario, London, Canada.
Desborough
K A
KA
McKitrick
D J
DJ
Ossenkopp
K P
KP
D000679:Amygdala / Q000503:physiopathology; D000818:Animals; D004292:Dominance, Cerebral / Q000502:physiology*; D004569:Electroencephalography; D005071:Evoked Potentials; D007696:Kindling, Neurologic; D008297:Male; D051381:Rats; D012640:Seizures / Q000503:physiopathology*