title: [Sensitivity of Pseudomonas mallei to sulfanilamide combinations in vitro].
abstract: It was shown that 9 strains of P. mallei were sensitive to sulfanilamides and their combinations with trimethoprim: sulfamonomethoxine + trimethoprim (2.5:1), sulfamethoxazole + trimethoprim (5:1) and sulfazin + trimethoprim (2.5:1 and 5:1). In regard to multiple lowering of the minimum bactericidal concentration of both drugs the combinations of sulfazin with trimethoprim (5:1 or 2.5:1) and sulfamethoxazole with trimethoprim (5:1) or biseptol proved to be the most active. The activity of the sulfamonomethoxine combination with trimethoprim (sulfate) was lower.
authors.forename: N A
authors.initials: NA
authors.lastname: Lozovaia
mesh_terms: D004338:Drug Combinations; D008826:Microbial Sensitivity Tests; D011549:Pseudomonas / Q000187:drug effects*; D013045:Species Specificity; D013424:Sulfanilamides / Q000008:administration & dosage / Q000494:pharmacology*; D014295:Trimethoprim / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D004338:Drug Combinations; D013424:Sulfanilamides; D014295:Trimethoprim
vernacular_title: Chuvstvitel'nost' Pseudomonas mallei k kombinirovannym sul'fanilamidam in vitro.