HIV-associated bronchiolitis obliterans organizing pneumonia.
A man with serologic evidence of HIV infection and a depressed T-helper:suppressor ratio developed fever, pulmonary infiltrates, and respiratory failure. Bronchoalveolar lavage and transbronchial biopsy failed to reveal an infectious cause; however, an open lung biopsy demonstrated classic bronchiolitis obliterans organizing pneumonia. The patient responded completely to corticosteroids. To the best of our knowledge, this represents a previously undescribed and readily treatable cause of respiratory failure in patients with HIV infections.
Allen
J N
JN
Ohio State University, Columbus.
Wewers
M D
MD
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D001706:Biopsy; D001989:Bronchiolitis Obliterans / Q000150:complications* / Q000175:diagnosis; D001992:Bronchoalveolar Lavage Fluid; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D011014:Pneumonia / Q000150:complications / Q000175:diagnosis