title: Mixed connective tissue disease after exposure to polyvinyl chloride.
abstract: We present 4 patients fulfilling criteria for mixed connective tissue disease (MCTD) with anti-RNP antibodies, who had been previously exposed, in 4 different professions, to polyvinyl chloride. This presentation is clinically and serologically different from the classical polyvinyl chloride disease in which no such antibody can be found. Already observed in patients after cosmetic surgery, MCTD could also be a result of toxic exposure.
authors.affiliation: Clinique de Rhumatologie, Faculté Xavier Bichat, Université Paris VII, France.
authors.forename: M F
authors.initials: MF
authors.lastname: Kahn
authors.forename: P
authors.initials: P
authors.lastname: Bourgeois
authors.forename: A
authors.initials: A
authors.lastname: Aeschlimann
authors.forename: P
authors.initials: P
authors.lastname: de Truchis
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008947:Mixed Connective Tissue Disease / Q000139:chemically induced*; D009784:Occupational Diseases / Q000139:chemically induced; D011143:Polyvinyl Chloride / Q000009:adverse effects*; D011145:Polyvinyls / Q000009:adverse effects*; D011928:Raynaud Disease / Q000503:physiopathology
chemical_list: D011145:Polyvinyls; D011143:Polyvinyl Chloride