[Relapsing polychondritis].
For three months a 17-year-old boy had been suffering from laryngitis, pharyngitis and conjunctivitis, weight loss, nocturnal sweating and signs of changing cranial-nerve involvement (dizziness, nausea, nystagmus). The diagnosis of recurrent polychondritis was made only when, in addition to a definite inspiratory stridor there also developed a painful swelling of the left ear cartilage and a saddle nose due to loss of the cartilaginous portion of the nasal skeleton. Histological examination of the inflamed ear cartilage confirmed the diagnosis. After treatment with prednisone (100 mg daily, gradually reduced to 25 mg) and azathioprine (100 mg daily, increased to 150 mg after three weeks), there was clinical improvement, but the airway resistance (R = 6.2 cm H2O.s/l) rose further, requiring tracheostoma twelve months after onset of symptoms.
Lamberts
R
R
Abteilung Gastroenterologie und Endokrinologie der Medizinischen Universitätsklinik Göttingen.
Helmchen
U
U
Creutzfeldt
W
W
D000293:Adolescent; D003231:Conjunctivitis / Q000175:diagnosis / Q000209:etiology; D003389:Cranial Nerve Diseases / Q000175:diagnosis / Q000209:etiology; D003937:Diagnosis, Differential; D004425:Ear Cartilage / Q000473:pathology; D006801:Humans; D007827:Laryngitis / Q000175:diagnosis / Q000209:etiology; D008297:Male; D009667:Nose Deformities, Acquired / Q000175:diagnosis / Q000209:etiology; D010612:Pharyngitis / Q000175:diagnosis / Q000209:etiology; D011081:Polychondritis, Relapsing / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D013546:Sweating; D015431:Weight Loss
Rezidivierende Polychrondritis.