Comparative QSAR analysis in dihydropteroate synthase inhibition by sulphones. Design and synthesis of some new derivatives with improved potency.
De Benedetti
P G
PG
Dipartimento di Chimica, dell'Università, Modena, Italy.
Iarossi
D
D
Frassineti
C
C
Menziani
M C
MC
Cocchi
M
M
Cennamo
C
C
D004094:Dihydropteroate Synthase / Q000037:antagonists & inhibitors*; D015195:Drug Design; D007700:Kinetics; D013329:Structure-Activity Relationship; D013450:Sulfones / Q000494:pharmacology*; D014166:Transferases / Q000037:antagonists & inhibitors*
D013450:Sulfones; D014166:Transferases; D004094:Dihydropteroate Synthase