[A comparative evaluation of tumor markers (TPA and CEA) in various malignant neoplasms at an advanced stage].
Radioimmunology was used to measure serum levels of CEA (carcinoembryonic antigen) in 108 patients with a variety of different advanced malignant neoplasms and in a control group of 60 healthy subjects. TPA proved more sensitive as a tumour marker than CEA, since increased TPA was found in 76% of the cancer cases compared to 42% for CEA. No significant increase in diagnostic sensitivity was obtained by using both markers rather than PTA alone.
Meregalli
M
M
U.S.S.L. n. 67, Ospedale S. Corona, Garbagnate Milanese.
Antoniazzi
V
V
Torchio
G
G
Colombo
E
E
Bocchi
M
M
Sonzini
E
E
Lino
S
S
D000951:Antigens, Neoplasm / Q000032:analysis*; D014408:Biomarkers, Tumor / Q000097:blood*; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000097:blood / Q000175:diagnosis*; D010455:Peptides / Q000032:analysis*; D011863:Radioimmunoassay; D019396:Tissue Polypeptide Antigen
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D010455:Peptides; D019396:Tissue Polypeptide Antigen
Valutazione comparata di marcatori tumorali (TPA e CEA) in differenti neoplasie maligne in stadio avanzato.