Use of neuroleptics after an episode of neuroleptic malignant syndrome.
The authors report a case of unequivocal Neuroleptic Malignant Syndrome, in which the patient was successfully rechallenged with a different potent neuroleptic in substantial dosage during the recovery phase. The Neuroleptic Malignant Syndrome did not recur and the patient's psychosis cleared. Reference is made to the relevant world literature.
Padgett
R
R
Department of Psychiatry, McMaster University, Hamilton, Ontario.
Lipman
E
E
D000293:Adolescent; D003989:Dibenzoxazepines / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D006801:Humans; D008152:Loxapine / Q000008:administration & dosage*; D008297:Male; D008728:Methotrimeprazine / Q000008:administration & dosage / Q000009:adverse effects*; D009459:Neuroleptic Malignant Syndrome / Q000209:etiology*; D012008:Recurrence; D012562:Schizophrenia, Disorganized / Q000188:drug therapy* / Q000523:psychology; D014268:Trifluoperazine / Q000008:administration & dosage / Q000009:adverse effects*
D003989:Dibenzoxazepines; D014268:Trifluoperazine; D008728:Methotrimeprazine; D008152:Loxapine