title: [Relapse of the stage I & II non-Hodgkin's lymphoma of the head and neck--factors relating to the chance of long-term survival].
abstract: A review has been made of 36 patients who, after initial treatment for early non-Hodgkin's lymphoma originating in the head or neck, incurred a relapse, and factors relating to their chances of long-term survival, i.e., greater than three years, have been sought. Informatively, the overall 1-year and 5-year survival after such a relapse has been 18% and 15% respectively. The factor most significantly related to long-term survival was the site of the lymphoma and the extent of the initial relapse. For those affected in the neck region alone, four out of five survived for more than 48 months after the relapse (p less than 0.0001). The pathological subtype of the initial lymphoma was the second most significant factor (p less than 0.02). Another factor drawing our attention was the history of the prophylactic adjuvant therapy. No patient survived for more than a year after relapse if they had a history of prophylactic adjuvant therapy (0/10), whereas five long-term survivors were patients with no history of such therapy (0.1 less than p less than 0.2).
authors.affiliation: Dept. of Radiology, School of Med., Hokkaido Univ.
authors.forename: T
authors.initials: T
authors.lastname: Arimoto
authors.forename: T
authors.initials: T
authors.lastname: Kitahara
authors.forename: M
authors.initials: M
authors.lastname: Myojin
authors.forename: A
authors.initials: A
authors.lastname: Takamura
authors.forename: S
authors.initials: S
authors.lastname: Matsuoka
authors.forename: H
authors.initials: H
authors.lastname: Shirato
authors.forename: G
authors.initials: G
authors.lastname: Irie
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000401:mortality* / Q000473:pathology / Q000628:therapy; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000401:mortality* / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012008:Recurrence; D012307:Risk Factors