Ratio of the R and S enantiomers of salsolinol in food and human urine.
Salsolinol is present in human fluids and tissues as well as in some foods and beverages. It was found previously that the R enantiomer of salsolinol predominates in human urine whereas the S enantiomer predominates in Port wine. In this study a new methodology for measuring the proportion of the R and S salsolinol enantiomers in dried banana and human urine is described. In dried banana, a food particularly rich in salsolinol, the R/S ratio was found to be very near to 1. In urine from additional healthy volunteers, the presence of only the R enantiomer was detected. The origin of urinary salsolinol and its enantiomeric composition are discussed with respect to exogenous salsolinol.
Strolin Benedetti
M
M
Farmitalia Carlo Erba, Research and Development, Milan, Italy.
Bellotti
V
V
Pianezzola
E
E
Moro
E
E
Carminati
P
P
Dostert
P
P
D000328:Adult; D005504:Food Analysis; D006801:Humans; D007546:Isoquinolines / Q000032:analysis / Q000652:urine*; D008297:Male; D008875:Middle Aged; D013237:Stereoisomerism
D007546:Isoquinolines; C036617:salsolinol