title: [A case of a combination heterozygote with hemoglobin K Woolwich and hemoglobin C (Hb Kw/HbC) discovered in Bobo-Dioulasso (Burkina Faso)].
abstract: During a study on malaria in pregnant women in Burkina Faso, the authors gave a particular attention to the hemoglobin of a mother and her new-born child (blood of cord) and they noticed an hemoglobin migrating before the HbA which was identified by isoelectric focusing (IEF). The child is a composite HbK/HbC heterozygote. A survey was carried out to check the transmission of such a K Woolwich hemoglobin within the family of the mother. Out of 40 people, 17 got HbKw. A noticeable anemia was found in HbKw/HbC heterozygote. The authors tried to identified a possible thalassemia. There was little probability for an association of a minor alpha-thalassemia in the absence of Bart's hemoglobin in the blood of the cord (IEF test) and there was no associated beta-thalassemia.
authors.affiliation: ORSTOM, Bobo-Dioulasso, Burkina Faso.
authors.forename: J F
authors.initials: JF
authors.lastname: Molez
authors.forename: F
authors.initials: F
authors.lastname: Galacteros
authors.forename: M F
authors.initials: MF
authors.lastname: Bosseno
authors.forename: D
authors.initials: D
authors.lastname: Haudrechy
authors.forename: E
authors.initials: E
authors.lastname: Kompaore
mesh_terms: D000328:Adult; D002050:Burkina Faso; D005260:Female; D005838:Genotype; D006444:Hemoglobin C / Q000032:analysis*; D006453:Hemoglobinopathies / Q000097:blood; D006455:Hemoglobins, Abnormal / Q000032:analysis* / Q000235:genetics; D006801:Humans; D007223:Infant; D008297:Male; D010375:Pedigree; D011247:Pregnancy
chemical_list: D006455:Hemoglobins, Abnormal; D006444:Hemoglobin C; C050153:hemoglobin K Woolwich
vernacular_title: Remarques à propos d'un hétérozygote composite présentant une hémoglobine K Woolwich et une hémoglobine C (Hb Kw/HbC) dépisté à Bobo-Dioulasso (Burkina Faso).