[Features of absorption of cortisol by peripheral blood cells in patients with bronchial asthma].
Hydrocortisone absorption by lymphocytes and red blood cells was reduced in patients with bronchial asthma (BA). Adrenaline produced the stimulatory effect on hydrocortisone absorption by lymphocytes and red blood cells in practically normal subjects and in BA patients in whom that effect was decreased. In patients with the steroid-dependent clinico-pathogenetic pattern of BA, hydrocortisone absorption by lymphocytes was reduced to a considerable degree. It is stressed that cellular mechanisms of glucocorticoid insufficiency are implicated in the BA pathogenesis.
Trofimov
V I
VI
Mineev
V N
VN
Zhikkharev
S S
SS
Karpov
O I
OI
D001249:Asthma / Q000097:blood*; D004837:Epinephrine / Q000502:physiology*; D004912:Erythrocytes / Q000378:metabolism* / Q000502:physiology; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008214:Lymphocytes / Q000378:metabolism* / Q000502:physiology
D006854:Hydrocortisone; D004837:Epinephrine
Osobennosti pogloshcheniia kortizola kletami perifericheskoĭ krovi u bol'nykh bronkhial'nu astmoĭ.