title: [Fecal chymotrypsin concentration in childhood. Normal values, specificity, sensitivity].
abstract: The determination of fecal chymotrypsin is a suitable noninvasive screening test for the evaluation of exocrine pancreatic function. Using a photometric assay we found a specificity of 87.5% and a sensitivity of 80%. Beyond the first year of life the lowest limit of normal values is 72 micrograms chymotrypsin/g stool. The method is reproducible, and a 72-hour stool collection is unnecessary when several fecal chymotrypsin determinations in spot stool samples are performed.
authors.forename: J
authors.initials: J
authors.lastname: Henker
authors.forename: S
authors.initials: S
authors.lastname: Hackbarth
authors.forename: C
authors.initials: C
authors.lastname: Sprössig
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002918:Chymotrypsin / Q000032:analysis*; D010188:Exocrine Pancreatic Insufficiency / Q000175:diagnosis*; D005243:Feces / Q000032:analysis*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000175:diagnosis*; D008297:Male; D010186:Pancreatic Function Tests; D012016:Reference Values
chemical_list: D002918:Chymotrypsin
vernacular_title: Stuhl-Chymotrypsin-Konzentration im Kindesalter. Normalwerte, Spezifität, Sensitivität.