Lectin-binding studies of a human skin mastocytoma.
A solitary mastocytoma of the skin was investigated to assess the lectin-binding pattern of human mast cells. Of 18 Fluorescein-labelled lectins tested, nine reacted with mast cell granules. While lectins recognizing N-acetylgalactosamine or fucose residues did not stain mast cells, lectins with binding sites for N-acetylglucosamine, alpha-methyl mannopyranoside, galactose, complex carbohydrates of N-acetyl-lactosamine type and sialic acid gave a positive reaction.
Schumacher
U
U
Department of Anatomy, University of Munich, W. Germany.
Horny
H P
HP
Welsch
U
U
Kaiserling
E
E
D006801:Humans; D037102:Lectins; D008407:Mast Cells / Q000473:pathology; D008415:Mastocytosis / Q000473:pathology*; D012867:Skin / Q000473:pathology*
D037102:Lectins