title: Evaluation of neurolytic blocks using phenol and cryogenic block in the management of chronic pain.
abstract: This study compared the use of phenol and cryogenic blocks for neurolysis in 28 patients. Patients were assigned randomly to receive peripheral nerve blocks with either phenol or cryoanalgesia. Significantly more patients in the phenol group received 20% or greater relief at 2, 12, and 24 wk than patients in the cryogenic group. Only 27% of patients received significant relief, however, indicating that neurolytic blocks were not particularly effective even though local anesthetic blocks produced significant but temporary pain relief.
authors.forename: S
authors.initials: S
authors.lastname: Ramamurthy
authors.forename: N E
authors.initials: NE
authors.lastname: Walsh
authors.forename: L S
authors.initials: LS
authors.lastname: Schoenfeld
authors.forename: J
authors.initials: J
authors.lastname: Hoffman
mesh_terms: D000328:Adult; D000368:Aged; D002908:Chronic Disease; D003452:Cryosurgery; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009407:Nerve Block / Q000379:methods*; D010146:Pain / Q000188:drug therapy / Q000209:etiology / Q000601:surgery; D010636:Phenols / Q000627:therapeutic use*; D011897:Random Allocation
chemical_list: D010636:Phenols