title: [Analysis of the correlation of indicators of utero-placental blood flow and various blood enzymes in pregnant women at high-risk of perinatal pathology].
abstract: A study of the correlations between uteroplacental flow (UPF) and some blood enzymes in 117 pregnant patients at high risk for perinatal disorders and with suspected placental insufficiency has demonstrated a stepwise activation of enzyme systems, which are elements of the adaptive-compensatory placental mechanisms, in the presence of placental insufficiency. UPF disorders in the intervillous space are of decisive importance for intrauterine fetal distress, as evidenced by the emerging correlations between UPF, and hydroxibutyrate dehydrogenase and lactate dehydrogenase. For this reason, it is proposed to expand indications for metabolic therapy and hyperbaric oxygenation in order to prevent intrauterine chronic fetal hypoxia.
authors.forename: V A
authors.initials: VA
authors.lastname: Burler
authors.forename: A I
authors.initials: AI
authors.lastname: Volobuev
authors.forename: A Zh
authors.initials: AZh
authors.lastname: Oganesian
authors.forename: E I
authors.initials: EI
authors.lastname: Vysokolian
mesh_terms: D000328:Adult; D004796:Clinical Enzyme Tests; D004789:Enzyme Activation; D005260:Female; D006801:Humans; D006884:Hydroxybutyrate Dehydrogenase / Q000097:blood*; D007511:Ischemia / Q000150:complications / Q000175:diagnosis*; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D010920:Placenta / Q000098:blood supply*; D010922:Placenta Diseases / Q000175:diagnosis*; D010927:Placental Insufficiency / Q000175:diagnosis* / Q000209:etiology; D011247:Pregnancy; D012307:Risk Factors; D014599:Uterus / Q000098:blood supply*
chemical_list: D007770:L-Lactate Dehydrogenase; D006884:Hydroxybutyrate Dehydrogenase
vernacular_title: Analiz korreliatsionnykh sviazeĭ mezhdu pokazateliami matochno-platsentarnogo krovotoka i nekotorymi fermentami krovi u beremennykh s vysokim riskom perinatal'noĭ patologii.