title: Unique inheritance of streptomycin-induced deafness.
abstract: Analysis of reported families which include two or more members with streptomycin-induced hearing loss reveals that the trait of high susceptibility of cochlea to streptomycin is transmitted primarily through females. This is not explained by ordinary Mendelian inheritance; rather it is best understood by extranuclear inheritance.
authors.affiliation: Department of Otolaryngology, School of Medicine, Akita University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Higashi
mesh_terms: D003051:Cochlea / Q000187:drug effects; D003638:Deafness / Q000139:chemically induced / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D010375:Pedigree; D012737:Sex Factors; D013307:Streptomycin / Q000009:adverse effects*
chemical_list: D013307:Streptomycin