Carpal tunnel syndrome in long-term hemodialyzed patients.
The etiopathology, clinical features, and treatment of carpal tunnel syndrome (CTS) in long-term hemodialyzed patients, are discussed in the light of new clinical findings. Conclusions summarizing the specific characteristics of CTS in hemodialyzed patients include the following. 1) There is a relatively equal sex ratio of patients. 2) The pathogenesis is complex and includes a) the presence of hemodynamic alterations related to the AV fistula; b) the presence of beta 2 M amyloid deposits related to biocompatibility of the dialysis membranes; and c) a correlation between CTS and the duration of hemodialysis related to years and hours/week. 3) A dramatic increase of CTS incidence occurs after five years of dialysis treatment. Prevention as a realistic goal in dialysis CTS is discussed, and specific recommendations are offered by the authors.
Corradi
M
M
Institute of Clinical Orthopedics and Traumatology, University of Parma, Italy.
Paganelli
E
E
Pavesi
G
G
D000368:Aged; D000682:Amyloid / Q000378:metabolism; D001166:Arteriovenous Shunt, Surgical; D002349:Carpal Tunnel Syndrome / Q000209:etiology* / Q000601:surgery; D004576:Electromyography; D005260:Female; D006801:Humans; D008297:Male; D008475:Median Nerve / Q000503:physiopathology; D008567:Membranes, Artificial; D008875:Middle Aged; D009431:Neural Conduction; D006435:Renal Dialysis; D013997:Time Factors
D000682:Amyloid; D008567:Membranes, Artificial