title: MR diagnosis of dural venous sinus thrombosis complicating L-asparaginase therapy.
abstract: Dural venous sinus thrombosis is an important complication of L-asparaginase chemotherapy. The diagnosis and followup of this condition, using spin echo and fast imaging techniques, is described in three patients. Magnetic Resonance (MR) imaging is a rapid, noninvasive technique for diagnosis and follow-up of this condition. Fast imaging techniques can improve the assessment of these patients.
authors.affiliation: Department of Radiology, Brigham and Womens Hospital, Harvard University, Boston, MA 02115.
authors.forename: R M
authors.initials: RM
authors.lastname: Schick
authors.forename: F
authors.initials: F
authors.lastname: Jolesz
authors.forename: P D
authors.initials: PD
authors.lastname: Barnes
authors.forename: J D
authors.initials: JD
authors.lastname: Macklis
mesh_terms: D000328:Adult; D001215:Asparaginase / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D004388:Dura Mater; D005500:Follow-Up Studies; D006801:Humans; D015461:Leukemia, Prolymphocytic, T-Cell / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D012851:Sinus Thrombosis, Intracranial / Q000139:chemically induced / Q000175:diagnosis*; D013997:Time Factors
chemical_list: D001215:Asparaginase