Surrogate human fallopian tubes for overcoming tubal infertility.
A procedure has been devised in order to establish a pregnancy in a patient with severe, untreatable tubal infertility who had unsuccessfully undergone tubal reconstructive surgery and repeated in-vitro fertilization procedures. This technique, which involves a volunteer, fertile woman, results from the combination of two infertility treatments: namely gamete intra-Fallopian transfer and uterine flushing. The gametes of the infertile couple were introduced into the distal tube of a synchronized volunteer woman; after 5 days, the embryos, recovered by lavage of the volunteer's uterus, were transferred into the patient's uterus with a resulting pregnancy and delivery.
Formigli
L
L
Centre for Reproductive Medicine, Milan, Italy.
Pagano
M
M
Roccio
C
C
Stangalini
A
A
Belotti
G
G
Coglitore
M T
MT
Formigli
G
G
D000328:Adult; D005184:Fallopian Tube Diseases / Q000150:complications* / Q000601:surgery; D005260:Female; D015181:Gamete Intrafallopian Transfer; D006801:Humans; D007247:Infertility, Female / Q000209:etiology* / Q000628:therapy; D009035:Mothers; D011247:Pregnancy; D013533:Gestational Carriers; D007507:Therapeutic Irrigation; D014599:Uterus