F-actin is involved in the polyethylene glycol-induced fusion of chick embryo fibroblasts.
Cytochalasin B inhibits the polyethylene glycol (PEG)-induced fusion of chick embryo fibroblasts. Induction of fusion of these cells by PEG is associated with transient changes in the pattern of F-actin organization within the cell. The changes include the disappearance of stress fibres and accumulation of F-actin under the plasma membrane. These results suggest an involvement of F-actin in PEG-induced cell fusion.
Kajstura
J
J
Department of Cell Biology, Jan Zurzycki Institute of Molecular Biology, Jagellonian University, Kraków, Poland.
D000199:Actins / Q000032:analysis / Q000502:physiology*; D000818:Animals; D002459:Cell Fusion / Q000187:drug effects; D002642:Chick Embryo; D003599:Cytoskeleton / Q000032:analysis / Q000502:physiology; D005347:Fibroblasts / Q000166:cytology* / Q000502:physiology / Q000648:ultrastructure; D011092:Polyethylene Glycols / Q000494:pharmacology*
D000199:Actins; D011092:Polyethylene Glycols