Taste. Robust across the age span?
The prevalence of taste loss over a discrete area of the tongue or palate is unknown; however, we have identified discrete losses in three etiological groups: head trauma, upper respiratory infection, and bulimia. We have now identified discrete losses in elderly subjects. To summarize, elderly subjects show elevated taste thresholds for some taste stimuli. Mild dysgeusia may act as a masking stimulus that makes taste thresholds appear to be elevated, and this may be more common in the elderly than the young. Discrete taste losses occur more often among the elderly than the young but usually go unnoticed (although these losses may contribute to elevated thresholds when the test procedure stimulates an area of loss). When the samples are at high concentrations, when the subject judges total intensity rather than typical quality, and when the whole mouth is used to do the tasting, the taste responses of elderly subjects look much like those of the young. Two factors contribute to the failure of people to notice localized taste loss. First, there appear to be mutually inhibitory connections between various taste loci such that if taste input from one area is blocked, the inhibition from that area is also blocked. This results in increases in perceived taste from the other areas. Second, a blank spot for taste can go unnoticed because taste is poorly localized. We can demonstrate this with an illusion. If a taste solution is painted from an area with receptors into an area that does not have receptors, the taste sensation seems to invade the area with no receptors. We suggest that a similar phenomenon may occur with areas from which receptors are lost. This localization illusion could then prevent a subject from noticing that an area has lost taste function. The discovery of discrete taste losses in a population of elderly subjects suggests that earlier failures to find substantial taste losses with age may reflect the redundancy of the taste system. This possibility raises the question of what functions taste subserves that require this kind of redundancy. The taste system appears to be "hard wired" to maintain the constancy of perceived intensity even if substantial taste areas are damaged. This constancy suggests that taste is serving important biological functions.(ABSTRACT TRUNCATED AT 400 WORDS)
Bartoshuk
L M
LM
John B. Pierce Foundation Laboratory, New Haven, Connecticut.
D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D000772:Anesthesia, Local; D002951:Citrates; D019343:Citric Acid; D004408:Dysgeusia; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011803:Quinine; D012965:Sodium Chloride; D013649:Taste / Q000502:physiology*; D013650:Taste Buds / Q000502:physiology
D002951:Citrates; D019343:Citric Acid; D012965:Sodium Chloride; D011803:Quinine