[Fecal chymotrypsin concentration in childhood. Normal values, specificity, sensitivity].
The determination of fecal chymotrypsin is a suitable noninvasive screening test for the evaluation of exocrine pancreatic function. Using a photometric assay we found a specificity of 87.5% and a sensitivity of 80%. Beyond the first year of life the lowest limit of normal values is 72 micrograms chymotrypsin/g stool. The method is reproducible, and a 72-hour stool collection is unnecessary when several fecal chymotrypsin determinations in spot stool samples are performed.
Henker
J
J
Hackbarth
S
S
Sprössig
C
C
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002918:Chymotrypsin / Q000032:analysis*; D010188:Exocrine Pancreatic Insufficiency / Q000175:diagnosis*; D005243:Feces / Q000032:analysis*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000175:diagnosis*; D008297:Male; D010186:Pancreatic Function Tests; D012016:Reference Values
D002918:Chymotrypsin
Stuhl-Chymotrypsin-Konzentration im Kindesalter. Normalwerte, Spezifität, Sensitivität.