[Clinical significance of cyclic nucleotide metabolism and calcium level in children with arrhythmia].
The cyclic nucleotides (CN) system and Ca2+ content were examined in children with various heart rhythm disorders (HRD). Marked changes were demonstrated which correlated to clinical manifestations of the arrhythmias: their type, phase, duration and favorable changes in their course. Antiarrhythmic therapy was associated with a normalization of the altered levels of cyclase components and Ca2+. The results suggest that intracellular metabolism regulation may be disrupted in HRD cases and play an important role in the development of arrhythmias.
Ternova
T I
TI
Bakanov
M I
MI
Bershova
T V
TV
Mikhaĭlova
I L
IL
Danilova
N V
NV
D000293:Adolescent; D001145:Arrhythmias, Cardiac / Q000097:blood* / Q000209:etiology; D002118:Calcium / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007962:Leukocytes / Q000378:metabolism*; D009712:Nucleotides, Cyclic / Q000097:blood*
D009712:Nucleotides, Cyclic; D002118:Calcium
Klinicheskoe znachenie osobennosteĭ obmena tsiklicheskikh nukleotidov i soderzhaniia ka'ltsiia pri aritmiiakh serdtsa u deteĭ.