Comparative in vitro antimicrobial susceptibilities of a special panel of 74 Bacteroides fragilis group isolates in Wilkins-Chalgren agar with and without sheep blood.
Seventy-four cefoxitin-resistant Bacteroides fragilis group isolates were tested by the serial twofold agar dilution method for susceptibility to imipenem and other agents in medium with and without 5% sheep blood. Imipenem (MIC for 90% of strains tested, 1 microgram/ml) and metronidazole (MIC for 90% of strains tested, 2 micrograms/ml) were the two most active agents. The addition of 5% sheep blood to the medium had little or no effect on the activity of the antibiotics tested.
Gill
C J
CJ
Clinical Microbiology Services, Merck and Co., Inc., Rahway, New Jersey 07065.
Shungu
D L
DL
Ponticas
S
S
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001441:Bacteroides fragilis / Q000187:drug effects*; D001769:Blood; D003470:Culture Media; D015378:Imipenem / Q000494:pharmacology; D008795:Metronidazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D012756:Sheep
D000900:Anti-Bacterial Agents; D003470:Culture Media; D008795:Metronidazole; D015378:Imipenem