A plant DNA-binding protein that recognizes 5-methylcytosine residues.
A novel, 5-methylcytosine-specific, DNA-binding protein, DBP-m, has been identified in nuclear extracts of peas. DBP-m specifically recognizes 5-methylcytosine residues in DNA without appreciable DNA sequence specificity, unlike a mammalian DNA-binding protein (MDBP), which recognizes 5-methylcytosine residues but only in a related family of 14-base-pair sequences.
Zhang
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Southern Regional Research Center, U.S. Department of Agriculture, New Orleans, Louisiana 70179.
Ehrlich
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KC
Supakar
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Ehrlich
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M
D044503:5-Methylcytosine; D001483:Base Sequence; D001665:Binding Sites; D003596:Cytosine / Q000031:analogs & derivatives* / Q000378:metabolism; D004247:DNA / Q000235:genetics / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000378:metabolism*; D008745:Methylation; D008969:Molecular Sequence Data; D010940:Plant Proteins / Q000378:metabolism*; D010944:Plants / Q000235:genetics / Q000378:metabolism
D004268:DNA-Binding Proteins; D010940:Plant Proteins; D044503:5-Methylcytosine; D003596:Cytosine; D004247:DNA