Lithium and Ebstein's anomaly.
The article deals with Ebstein's anomaly, lithium and their relationship. Some studies suggest that lithium might be involved as a teratogen increasing the incidence of Ebstein's anomaly in the offspring of female patients with manio-depressive psychosis and lithium-administered during pregnancy. The second part of the article contains data on the incidence of Ebstein's anomaly in the Czech Socialist Republic between 1960 and 1985. The results indicate a steady rise in the incidence of this congenital malformation over the above period of time.
Sípek
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Institute of Care for Mother and Child, Prague, Czechoslovakia.
D001714:Bipolar Disorder / Q000188:drug therapy*; D004437:Ebstein Anomaly / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008094:Lithium / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D012307:Risk Factors
D008094:Lithium