title: [Anti-infection prophylaxis in cardiac surgery: comparison of single-dose ceftriaxone and cefamandole in repeat doses].
abstract: The efficiency of a single two gram bolus of Ceftriaxone for cardiac operations was evaluated versus a classical, multiple dose, antibiotic prophylaxis using Cefamandole. The results were quite similar in both groups, with a very low infection rate. We conclude that a single bolus prophylaxis using a broad spectrum antibiotic is as efficient as an ordinary, multiple dose technique.
authors.forename: P
authors.initials: P
authors.lastname: Badel
authors.forename: M
authors.initials: M
authors.lastname: Schmuziger
mesh_terms: D000368:Aged; D006348:Cardiac Surgical Procedures; D002435:Cefamandole / Q000008:administration & dosage*; D002443:Ceftriaxone / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013530:Surgical Wound Infection / Q000517:prevention & control*
chemical_list: D002435:Cefamandole; D002443:Ceftriaxone
vernacular_title: Prophylaxie anti-infectieuse en chirurgie cardiaque: comparaison entre la ceftriaxone en dose unique et le céfamandole en doses répétées.