[Effect of a tetrahydroxazine derivative on conditioned and unconditioned reflexes of experimental animals].
The influence of a newly synthesized tetrahydroxalic derivative with aphrodistatic action under the code name of PC-1 was studied in white rats of Wistar strain on conditioned and unconditioned reactions for avoidance of averse stimuli (sound, light, electric current with tension of 30 volts). The experiments were carried out on nonavoiding animals, selected in advance. Parallel experiments were undertaken with the preparation Imipramine (Pharmachim). The results showed that PC-1 affected positively conditioned reflex activity, manifested by shortening of latency of avoidance and by an increase of their number.
Ilarionov
I
I
Danchev
N
N
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects; D003214:Conditioning, Classical; D007099:Imipramine / Q000494:pharmacology; D009025:Morpholines / Q000494:pharmacology*; D011427:Propiophenones / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D012018:Reflex / Q000187:drug effects*
D009025:Morpholines; D011427:Propiophenones; C058603:2-methyl-3-(2-methyl-2,3-diphenyl-4-morpholinyl)-1-phenyl-1-propanone; D007099:Imipramine
Vliianie na edno tetrakhidroksazinovo prozvodno vŭrkhu uslovno- i bezuslovnoreflektornata deĭnost u opitin zhivotni.