[Dependence of the thrombocyte aggregation reaction on plasma fibronectin and the tripeptide arginyl-glycyl-asparagilin].
If was shown that the addition of fibronectin antibodies exerted the inhibition of platelet aggregation. The tripeptide RGD inhibited the platelet aggregation induced by the same agents (ADP, epinephrine, thrombin, collagen) both in blood plasma and in suspension of washed platelets.
Iuranek
I O
IO
Fedorov
N A
NA
Titov
M I
MI
Deĭgin
V I
VI
D000906:Antibodies / Q000276:immunology; D000918:Antibody Specificity / Q000187:drug effects; D001666:Binding Sites, Antibody / Q000187:drug effects; D003864:Depression, Chemical; D004305:Dose-Response Relationship, Drug; D004306:Dose-Response Relationship, Immunologic; D005353:Fibronectins / Q000097:blood* / Q000276:immunology / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D009842:Oligopeptides / Q000494:pharmacology*; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology*; D011971:Receptors, Immunologic / Q000187:drug effects* / Q000502:physiology
D000906:Antibodies; D005353:Fibronectins; D009842:Oligopeptides; D010975:Platelet Aggregation Inhibitors; D011971:Receptors, Immunologic; C047981:arginyl-glycyl-aspartic acid
Zavisimost' reaktsii agregatsii trombotsitov ot fibronektina plazmy i tripetida arginil-glitsil-asparagilin.