title: Diabetes mellitus in primary glaucomas.
abstract: The association between diabetes mellitus and primary glaucomas is evaluated. Diabetes is specifically associated with narrow-angle categories of primary glaucoma: closed-angle glaucoma and narrow-angle patients with ocular hypertension or open-angle glaucoma. The prevalence of diabetes mellitus in wide-angle glaucoma patients is not significantly different from normal age-matched control subjects. The association between diabetes and glaucoma is restricted to non-insulin dependent diabetes mellitus and impaired glucose tolerance; the prevalence of insulin-dependent diabetes mellitus in the primary glaucomas is equivalent to age-matched normal values. These conclusions are supported by 75-gram oral glucose tolerance testing, estimation of glycosylated haemoglobin, retrospective analysis of positive diabetic family history, and prospective follow-up examining progression of impaired glucose tolerance to diabetes mellitus in patients with primary glaucoma.
authors.affiliation: Princess Alexandra Eye Pavilion, Edinburgh, United Kingdom.
authors.forename: C V
authors.initials: CV
authors.lastname: Clark
mesh_terms: D000867:Anterior Chamber / Q000033:anatomy & histology; D001786:Blood Glucose; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D005500:Follow-Up Studies; D005901:Glaucoma / Q000150:complications*; D005902:Glaucoma, Open-Angle / Q000150:complications; D005951:Glucose Tolerance Test; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D009798:Ocular Hypertension / Q000150:complications; D012189:Retrospective Studies
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin