title: Effects of coffee on plasma lipids, lipoproteins and apolipoproteins.
abstract: The acute effects of coffee, cigarette smoking and alcohol on serum lipids, lipoproteins and thromboxane B2 production by platelets were studied in nine healthy volunteers who were non-drinkers of coffee and alcohol and non-smokers. They received, in a single administration, coffee (containing 200 mg of caffeine), alcohol (0.50 ml/kg body wt), or smoked two cigarettes. No differences were observed between baseline and 15, 60 and 80 min values for plasma cholesterol, triglycerides, HDL cholesterol, plasma apolipoproteins A-I and B and thromboxane B2 production. Chronic coffee consumption also did not affect either plasma lipoprotein profile or the interaction of low density lipoproteins with cellular receptors in a group of healthy individuals. These results suggest that coffee itself does not affect acutely the plasma lipoprotein profile in healthy man. This was also true in heavy coffee drinkers.
authors.affiliation: Institute of Pharmacological Sciences, Milano, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Paoletti
authors.forename: A
authors.initials: A
authors.lastname: Corsini
authors.forename: E
authors.initials: E
authors.lastname: Tremoli
authors.forename: R
authors.initials: R
authors.lastname: Fumagalli
authors.forename: A L
authors.initials: AL
authors.lastname: Catapano
mesh_terms: D000328:Adult; D001053:Apolipoproteins / Q000097:blood*; D002784:Cholesterol / Q000097:blood; D003069:Coffee; D006801:Humans; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D013929:Thromboxane B2 / Q000096:biosynthesis
chemical_list: D001053:Apolipoproteins; D003069:Coffee; D008055:Lipids; D008074:Lipoproteins; D013929:Thromboxane B2; D002784:Cholesterol