title: Haemolytic-uraemic syndrome associated with Streptococcus pneumoniae meningitis.
abstract: We report the first case of Haemolytic-uraemic syndrome (HUS) associated with Streptococcus pneumoniae meningitis. This supports a common pathogenic mechanism in HUS following infections by neuraminidase-producing organisms and in pneumococcal meningitis. We recommend that HUS must be considered in cases of renal failure and/or anaemia associated with pneumococcal meningitis, and that bacterial meningitis be considered in all patients with HUS and central nervous system involvement.
authors.affiliation: Paediatric Intensive Care Unit, Université de Lille, Hôpital Calmette, France.
authors.forename: A
authors.initials: A
authors.lastname: Martinot
authors.forename: V
authors.initials: V
authors.lastname: Hue
authors.forename: F
authors.initials: F
authors.lastname: Leclerc
authors.forename: M
authors.initials: M
authors.lastname: Chenaud
mesh_terms: D006463:Hemolytic-Uremic Syndrome / Q000150:complications*; D006801:Humans; D007223:Infant; D008297:Male; D008586:Meningitis, Pneumococcal / Q000150:complications*; D009439:Neuraminidase / Q000378:metabolism; D013296:Streptococcus pneumoniae / Q000201:enzymology
chemical_list: D009439:Neuraminidase