Transient neonatal diabetes mellitus in a pair of twins.
The occurrence of transient neonatal diabetes mellitus in male twins with almost identical courses of illness is reported. A trial with chlorpropamide treatment of twin A had no obvious influence on the insulin consumption or on duration of treatment. Very low values of plasma C-peptide and serum proinsulin with no detectable insulin antibodies supports the theory of delayed maturation of the beta-cell.
Nielsen
F
F
Department of Pediatrics, Sønderborg sygehus, Denmark.
D002747:Chlorpropamide / Q000627:therapeutic use*; D003920:Diabetes Mellitus / Q000097:blood / Q000188:drug therapy*; D004200:Diseases in Twins; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male
D002747:Chlorpropamide