[Basic characteristics of a live influenza vaccine for children from type A influenza (H1N1 and H3N2) used separately and in combination].
The study of safety and immunizing properties of a live influenza vaccine from influenza viruses type A (H1N1) and A (H3N2) used separately and in combination was carried out in 2461 children ranging in age from 3 to 15 years. The possibility of combining two influenza type A viruses with similar biological activity was demonstrated. The vaccine exerted no harmful effect in children and actively stimulated the production of antihemagglutinating, antineuraminidase, and secretory antibodies and enhanced the formation of cell-mediated immunity.
Rudenko
L G
LG
Shvartsman
Ia S
IaS
Ispolatova
A V
AV
Grigor'eva
E P
EP
Drinevskiĭ
V P
VP
D000293:Adolescent; D000914:Antibodies, Viral / Q000096:biosynthesis* / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D006389:Hemagglutinins, Viral / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D053118:Influenza A Virus, H1N1 Subtype; D053122:Influenza A Virus, H3N2 Subtype; D009980:Influenza A virus / Q000276:immunology*; D007252:Influenza Vaccines / Q000276:immunology*; D007251:Influenza, Human / Q000276:immunology / Q000517:prevention & control*; D008214:Lymphocytes / Q000276:immunology; D009439:Neuraminidase / Q000276:immunology
D000914:Antibodies, Viral; D006389:Hemagglutinins, Viral; D007252:Influenza Vaccines; D009439:Neuraminidase
Osnovnye kharakteristiki zhivoĭ grippoznoĭ vaktsiny dlia deteĭ iz shtammov virusov grippa A (H1N1) i A (H3N2) pri razdel'nom i sovmestnom ikh primenenii.