title: Neurosignal analysis during saccadic eye movements.
abstract: An inverse method is developed to investigate the oculomotor neural control signal. The oculomotor plant is modeled with a fourth-order linear homeomorphic saccadic eye movement model. Parameter estimation is performed using a conjugate gradient search method which minimizes the integral of the absolute value of the error squared between the model and the data. Derivatives are computed using band-limited differentiation (BLD) techniques and the results are compared to derivatives computed using the two-point central difference method. Using the BLD technique allows for greater flexibility in choosing a cutoff frequency, provides true low-pass filtering above the cutoff frequency, and gives more consistent results than using the two-point central difference method. The input to the oculomotor plant model is computed. The input is a cumulative force consisting of the agonist and antagonist active state tensions and their respective rate-of-change terms. The agonist force is also determined by approximating the antagonist active state tension and removing if from the cumulative input force.
authors.forename: R B
authors.initials: RB
authors.lastname: Weigel
authors.forename: J D
authors.initials: JD
authors.lastname: Enderle
authors.forename: E J
authors.initials: EJ
authors.lastname: Engelken
mesh_terms: D004585:Electrooculography / Q000295:instrumentation*; D005133:Eye Movements; D006801:Humans; D008959:Models, Neurological; D009802:Oculomotor Nerve / Q000502:physiology*; D012438:Saccades; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*