title: Manganese absorption from human milk, cow's milk, and infant formulas in humans.
abstract: Manganese absorption from human milk, cow's milk, and infant formulas was studied in humans by using extrinsic labeling of the diets with manganese 54 or manganese 52 and whole-body retention measurements. The fractional manganese absorption from human milk (8.2% +/- 2.9%) was significantly different when compared with cow's milk (2.4% +/- 1.7%), soy formula (0.7% +/- 0.2%), and whey-preponderant cow's milk formula with 12 mg/L of iron (1.7% +/- 1.0%) and without iron fortification (2 mg/L of iron) (3.1% +/- 2.8%), while no significant difference was observed between a whey-preponderant cow's milk formula with 7 mg/L of iron (5.9% +/- 4.8%) and human milk. The total amount of absorbed manganese was significantly higher from the non--iron-fortified cow's milk formula (2 mg/L of iron) as compared with human milk, while no significant differences were observed for the other milks and formulas.
authors.affiliation: Department of Clinical Nutrition, University of Gothenburg, Sahlgrenska Hospital, Göteborg, Sweden.
authors.forename: L
authors.initials: L
authors.lastname: Davidsson
authors.forename: A
authors.initials: A
authors.lastname: Cederblad
authors.forename: B
authors.initials: B
authors.lastname: Lönnerdal
authors.forename: B
authors.initials: B
authors.lastname: Sandström
mesh_terms: D000042:Absorption; D000328:Adult; D000818:Animals; D005260:Female; D006801:Humans; D007225:Infant Food / Q000032:analysis; D007501:Iron / Q000008:administration & dosage; D008297:Male; D008345:Manganese / Q000008:administration & dosage / Q000493:pharmacokinetics*; D008875:Middle Aged; D008892:Milk / Q000032:analysis; D008895:Milk, Human / Q000032:analysis
chemical_list: D008345:Manganese; D007501:Iron