[Levels of HDL cholesterol and the HDL2 and HDL3 subfractions in newly detected type 2 diabetes].
In a group of 40 newly detected middle-aged diabetics the authors recorded reduced HDL cholesterol levels and elevated triglyceride and total cholesterol levels. After compensation of diabetes the cholesterol and triglyceride levels became normal, the HDL cholesterol levels remained, however, low. By comparison of the sub-fractions of HDL cholesterol in diabetics with the control group it was revealed that in the diabetic group the HDL2 cholesterol levels were significantly reduced. The HDL3 cholesterol was not significantly altered. The reduction of the total HDL cholesterol was due mainly to low HDL2 cholesterol, while the HDL3 cholesterol level was normal. Low HDL cholesterol levels and those of the HDL2 sub-fraction in newly detected diabetics indicate the increased risk of development of atherosclerosis.
Brunová
J
J
Válek
J
J
Grafnetter
D
D
Karasová
L
L
D008076:Cholesterol, HDL / Q000097:blood*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood*; D053439:Lipoproteins, HDL2; D053440:Lipoproteins, HDL3; D008297:Male; D008875:Middle Aged
D008076:Cholesterol, HDL; D008075:Lipoproteins, HDL; D053439:Lipoproteins, HDL2; D053440:Lipoproteins, HDL3
Hodnoty HDL cholesterolu a jeho subfrakcí HDL2 a HDL3 u novĕ zjistĕných diabetiků 2. typu.