[A case report of a giant cell carcinoma of the thyroid].
Discussed is a case of a giant cell carcinoma that presented a high value of serum thyroglobulin. Histopathologically, this tumor had been diagnosed as being an anaplastic carcinoma that had transformed from a differentiated carcinoma, with calcification that was thought to have occurred from a preceding adenoma. To study the possibility of a malignant transformation, an immunohistochemical study of a specimen confirmed the production of thyroglobulin and vimentin, though the specimen stained negatively for keratin.
Murakami
N
N
1st Dept. of Surgery, Kanazawa Univ. School of Med.
Kawaura
Y
Y
Sasaki
M
M
Munemoto
Y
Y
Iwa
T
T
Nonomura
A
A
D000368:Aged; D002114:Calcinosis / Q000473:pathology; D002277:Carcinoma / Q000097:blood / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D013954:Thyroglobulin / Q000096:biosynthesis / Q000097:blood; D013964:Thyroid Neoplasms / Q000097:blood / Q000378:metabolism / Q000473:pathology*; D014746:Vimentin / Q000096:biosynthesis
D014746:Vimentin; D013954:Thyroglobulin