title: [Variant angina due to deficiency of intracellular magnesium by anorexia nervosa].
abstract: A 51-year-old man who had a past history of gastric resection for medically uncontrollable gastric ulcer has loss of appetite that recurs periodically. And he has frequently presented spontaneous angina early in the morning since 1984. He was diagnosed as having variant angina by the documentation of typical ST elevation during anginal attack and also by showing coronary artery spasm (#2 and #12) during hyperventilation on coronary arteriography. A large quantity of calcium blocking agents and nitrates could not improve his symptoms. Lack of intracellular magnesium by loss of appetite was suspected from a daily excretion of urine magnesium (5.3 mEq) and magnesium tolerance test (56.7%). To confirm the effect of magnesium administration, the second coronary arteriography was performed. After magnesium sulphate (80 mEq, hourly) was injected, coronary artery spasm could not be induced by ergonovine. And orally magnesium oxide, calcium blocking agents and nitrates were started. Anginal attack disappeared with increasing urine magnesium.
authors.forename: K
authors.initials: K
authors.lastname: Tanabe
authors.forename: K
authors.initials: K
authors.lastname: Noda
authors.forename: A
authors.initials: A
authors.lastname: Masaka
authors.forename: C
authors.initials: C
authors.lastname: Nakanishi
authors.forename: S
authors.initials: S
authors.lastname: Arai
authors.forename: Y
authors.initials: Y
authors.lastname: Kishi
authors.forename: K
authors.initials: K
authors.lastname: Sotozono
authors.forename: M
authors.initials: M
authors.lastname: Kamegai
authors.forename: F
authors.initials: F
authors.lastname: Miyake
authors.forename: T
authors.initials: T
authors.lastname: Mikawa
mesh_terms: D000788:Angina Pectoris, Variant / Q000188:drug therapy / Q000209:etiology*; D000856:Anorexia Nervosa / Q000150:complications*; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D006801:Humans; D008275:Magnesium Deficiency / Q000150:complications*; D008277:Magnesium Oxide / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009566:Nitrates / Q000627:therapeutic use
chemical_list: D002121:Calcium Channel Blockers; D009566:Nitrates; D008277:Magnesium Oxide