[A simple model for verifying the effects of a focused shock wave from our generator on erythrocytes and lymphocytes].
Biological effects of the focused shock wave produced by the generator of our own construction were observed on the erythrocyte and lymphocyte suspension as a model. Erythrocyte haemolysis located into the small volume of the 1.4 ml focus was observed in the dependence on the number of shocks. After 10 shocks it does not exceed 15%. In the previous experiments this particular dosage caused a complete destruction of the bile stone of about 1 cm size. Increase of kalium concentration in correspondence to the degree of haemolysis was discovered in the erythrocyte suspension. Effects of shock wave were observed also in lymphocytes, where no change of blastic transformation in the decrease of the life span approximately by 2% was proved. Regular measurements proved minimum damage of blood cells in given experimental conditions and the results are comparable with biological effects of other sources of the focused shock wave.
Benes
J
J
Sindelka
G
G
Kordac
V
V
Soucek
J
J
Jirsa
M
M
Sunka
P
P
D004912:Erythrocytes / Q000502:physiology*; D006461:Hemolysis; D006801:Humans; D008096:Lithotripsy; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology*
Jednoduchý model pro ovĕrení úcinků vlastního zdroje fokusované rázové vlny exponováním erytrocytů a lymfocytů.