Study of local anaesthetics. Part 93: A contribution to the study of OSAR in the group of derivatives of phenylcarbamic acid.
The present paper has been focussed on the study of quantitative relations between structure, physico-chemical properties and biological activity in the series of substances with potential local anaesthetic and beta-adrenolytic effectiveness from the group of phenylcarbamic acid derivatives. The study of the above-mentioned relations and their interpretation could contribute to the optimization of new potential medicaments.
Bachratá
M
M
Department of Pharmaceutical Chemistry, Pharmaceutical Faculty, University of J.A. Komensky, Bratislava, Czechoslovakia.
Stankovicová
M
M
Bezáková
Z
Z
Blesová
M
M
Cizmárik
J
J
Csöllei
J
J
Borovanský
A
A
D000779:Anesthetics, Local / Q000494:pharmacology*; D002219:Carbamates / Q000138:chemical synthesis* / Q000494:pharmacology; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D010880:Piperidines / Q000138:chemical synthesis* / Q000494:pharmacology; D013329:Structure-Activity Relationship
D000779:Anesthetics, Local; D002219:Carbamates; D010880:Piperidines; C059692:phenylcarbamic acid