The direct observation of a psoralen-thymine UVA induced solid-state cycloaddition reaction product by single-crystal x-ray diffractometry.
Single-crystal x-ray diffraction methods have been used to directly observe and simultaneously determine the molecular structure of the UVA induced cis-syn photocycloaddition product in a partially photolyzed single crystal of a psoralen(pyrone ring side)-DNA(thymine) interaction model compound, 1'-(8-oxypsoralen)-8'(thym-1"yl)3',6'-dioxaoctane.
Pfluger
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Ostrander
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D004249:DNA Damage; D011564:Furocoumarins; D008958:Models, Molecular; D010777:Photochemistry; D013941:Thymine; D014466:Ultraviolet Rays; D014961:X-Ray Diffraction
D011564:Furocoumarins; D013941:Thymine