[Entrapping of hydrophobized plague capsular antigen into large unilamellar liposomes].
The entrapping of a plague capsular antigen into the liposomes, prepared by the "reverse phase" evaporating method, was investigated. Both the native antigen and the antigen modified by palmitoylchloride were used. The entrapping of the modified antigen into the liposomes was greater than that of the native one: 46.1 +/- 5.4% and 3.7 +/- 2.7%, respectively. The highest content of the antigen on the membrane surface was observed when using palmitoylized protein and liposomes with egg lecithin, cholesterol and dicethylphosphate in the molar ratio 7:2:1.
Zakrevskiĭ
V I
VI
Plekhanova
N G
NG
Smirnova
V I
VI
D000942:Antigens, Bacterial / Q000302:isolation & purification*; D007202:Indicators and Reagents; D008081:Liposomes / Q000276:immunology*; D015010:Yersinia pestis / Q000276:immunology*
D000942:Antigens, Bacterial; D007202:Indicators and Reagents; D008081:Liposomes
Vkliuchenie gidrofobizovannogo kapsul'nogo antigena chumnogo mikroba v bol'shie oligosloĭnye liposomy.