Localization in man of fifteen DNA sequences within the chromosome segment 13q12-q22.
Fifteen human chromosome 13 specific DNA fragments, isolated from a lambda phage genomic library, were localized within the segment 13q12-q22. One was mapped to 13q12.1-q12.2, three to 13q12.3-q13.1, one to 13q14,1-q14.2, five to 13q14.1-q21.1, one to 13q21.1-q21.2, two to 13q21.2, and one to 13q22.1, and one to 13q22. The localization was performed by hybridization to Southern blots of a panel of human cell lines with overlapping deletions in 13q, and for three probes also by in situ hybridization to metaphase chromosomes.
Arheden
K
K
Tantravahi
U
U
Tommerup
N
N
Tranebjaerg
L
L
Mitelman
F
F
D002460:Cell Line; D002874:Chromosome Mapping; D002882:Chromosomes, Human, Pair 13 / Q000648:ultrastructure*; D002894:Chromosomes, Human, Pair 4; D004247:DNA / Q000032:analysis*; D015342:DNA Probes; D005347:Fibroblasts / Q000648:ultrastructure; D015321:Gene Rearrangement; D005819:Genetic Markers; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure; D009693:Nucleic Acid Hybridization; D014178:Translocation, Genetic
D015342:DNA Probes; D005819:Genetic Markers; D004247:DNA