title: [Ex vivo study of the effect of ribomunyl on the release of oxygen radicals by polynuclear neutrophils].
abstract: The ex vivo study of the chemiluminescence index of polynuclear neutrophils before and after treatment of 6 children who were receiving injectable Ribomunyl for ORL infections showed an increase of more than 600% of the mean value of the index after treatment. Ribomunyl therefore potentiates the bactericidal activity of polynuclear neutrophils.
authors.affiliation: Service de Pédiatrie, CHI, Créteil.
authors.forename: M C
authors.initials: MC
authors.lastname: Rahimy
authors.forename: F
authors.initials: F
authors.lastname: Bernaudin
authors.forename: E
authors.initials: E
authors.lastname: Doppelt
authors.forename: F
authors.initials: F
authors.lastname: de la Rocque
authors.forename: D
authors.initials: D
authors.lastname: Plan
authors.forename: P H
authors.initials: PH
authors.lastname: Reinert
authors.forename: J F
authors.initials: JF
authors.lastname: Bernaudin
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000942:Antigens, Bacterial / Q000494:pharmacology*; D001424:Bacterial Infections / Q000628:therapy*; D005609:Free Radicals; D006801:Humans; D007167:Immunotherapy; D009504:Neutrophils / Q000187:drug effects*; D010038:Otorhinolaryngologic Diseases / Q000628:therapy*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000097:blood; D012270:Ribosomes
chemical_list: D000276:Adjuvants, Immunologic; D000942:Antigens, Bacterial; D005609:Free Radicals; C034206:Ribomunyl; D010100:Oxygen
vernacular_title: Etude ex vivo de l'effet du ribomunyl sur le relargage des radicaux oxydants par les polynucléaires neutrophiles.