title: Management of labor in patients with idiopathic thrombocytopenic purpura.
abstract: Transient thrombocytopenia may occur in infants born to mothers with idiopathic thrombocytopenic purpura, suggesting transplacental passage of the antiplatelet factor. Labor in women with idiopathic thrombocytopenic purpura calls for a special management. Irrespective of the maternal platelet count, we believe that labor should be conducted vaginally but reassessed after a thrombocyte count of fetal scalp blood. Maternal thrombocytopenia, which may indicate a possible risk of coagulopathy, should be treated aggressively and followed up with replacement therapy. Percutaneous umbilical sampling is to be avoided because it carries an immediate risk of fetal and maternal complications. A count of 50,000/mm3, obtained early during the course of labor, may be taken as a threshold indicator for abdominal delivery via cesarean section.
authors.affiliation: Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel Hashomer, Israel.
authors.forename: U
authors.initials: U
authors.lastname: Dan
authors.forename: G
authors.initials: G
authors.lastname: Barkai
authors.forename: B
authors.initials: B
authors.lastname: David
authors.forename: M
authors.initials: M
authors.lastname: Goldenberg
authors.forename: E
authors.initials: E
authors.lastname: Kukkia
authors.forename: S
authors.initials: S
authors.lastname: Mashiach
mesh_terms: D001792:Blood Platelets; D005260:Female; D005312:Fetal Blood / Q000032:analysis*; D006801:Humans; D007743:Labor, Obstetric; D010976:Platelet Count; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood / Q000628:therapy*; D011696:Purpura, Thrombocytopenic / Q000097:blood / Q000628:therapy*; D012535:Scalp / Q000098:blood supply