[Use of the polymorphism of flanking DNA probes with respect to the Xq-27 region in a great fragile X pedigree].
We analyzed the segregation between fragile site Xq 27 and flanking polymorphic probes (52A, for factor 9, 4D-8, for factor 8, St14 and MN12) in a great Xq-fra pedigree. On the basis of these data, the use of these probes is discussed in view of its value as a diagnostic tool.
Berriche
S
S
Laboratoire de Génétique Moléculaire de l'INTS, Paris.
David
F
F
Lucotte
G
G
D015342:DNA Probes; D005260:Female; D005600:Fragile X Syndrome / Q000175:diagnosis*; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000235:genetics*; D010375:Pedigree; D011110:Polymorphism, Genetic; D011995:Recombination, Genetic; D012729:Sex Chromosome Aberrations / Q000175:diagnosis*
D015342:DNA Probes
Utilisation du polymorphisme des sondes flanquantes par rapport au site Xq-27 dans une grande généalogie X-fragile.