title: Inductively coupled plasma mass spectrometric determination of the absorption of iron in normal women.
abstract: The determination of iron isotope ratios in blood, without prior sample preparation, using inductively coupled plasma mass spectrometry (ICP-MS) with sample introduction by electrothermal vaporisation (ETV) is described. Following oral administration of 5 mg of enriched 54FeSO4 and intravenous administration of 200 micrograms of 57FeSO4 to non-pregnant women, the 54Fe: 56Fe and 57Fe: 56Fe isotope ratios in serum were measured reliably within 20 min per sample in quintuplicate. Changes in the fractional absorption of iron during human pregnancy could therefore be assessed.
authors.forename: P G
authors.initials: PG
authors.lastname: Whittaker
authors.forename: T
authors.initials: T
authors.lastname: Lind
authors.forename: J G
authors.initials: JG
authors.lastname: Williams
authors.forename: A L
authors.initials: AL
authors.lastname: Gray
mesh_terms: D005260:Female; D006801:Humans; D007501:Iron / Q000097:blood*; D013058:Mass Spectrometry / Q000379:methods; D012016:Reference Values
chemical_list: D007501:Iron