title: [Use of an immunoglobulin with targeted action for the prevention and treatment of recurrent herpetic stomatitis in children].
abstract: The results of parenteral (2 to 3 injections of 1.5 to 3 ml once on 3-rd to 4-th day) application of the prepared immunoglobulin with the titer of antiherpetic antibodies of 1:512 to 1:1024 in combined treatment of 2 groups of patients are summarized. In 34 children aged 2 to 12 years recurrent herpetic stomatitis was at its exacerbation. In 27 patients aged 1 to 3 an acute (primary) herpetic stomatitis was present and the group was considered, on grounds of the originally designed prognostic system, as being at high risk of transition into the chronic frequently exacerbating form of the disease. Positive immediate anti-recidive and preventive effect was obtained and confirmed in 12 to 24 months' follow-up.
authors.forename: E M
authors.initials: EM
authors.lastname: Mel'nichenko
authors.forename: A G
authors.initials: AG
authors.lastname: Kolomiets
mesh_terms: D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D005500:Follow-Up Studies; D006801:Humans; D007116:Immunization, Passive / Q000379:methods; D007223:Infant; D012008:Recurrence; D012307:Risk Factors; D013283:Stomatitis, Herpetic / Q000517:prevention & control* / Q000628:therapy
vernacular_title: Primenenie immunoglobulina napravlennogo deĭstviia dlia profilaktiki i lecheniia retsidiviruiushchego gerpeticheskogo stomatita u deteĭ.