[Determination of matrix components in the synovial fluid and blood--a novel approach to studying cartilage involvement in joint disease].
Information on the structure and metabolism of a number of matrix constituents of cartilage has accumulated rapidly during the last decades. Altered dynamics of cartilage matrix in joint diseases results in increased release of macromolecules, which are now explored as potential markers of damage and severity. This article highlights some recent progress in this field with emphasis on cartilage derived proteoglycan. Disease and therapy related changes may be studied and prognostic information may be obtained by analysis of joint fluid. Future applications of this approach are promising.
Saxne
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D001774:Blood Chemical Analysis; D001842:Bone and Bones / Q000378:metabolism / Q000473:pathology*; D002356:Cartilage / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007592:Joint Diseases / Q000378:metabolism*; D013582:Synovial Fluid / Q000032:analysis*
Bestämning av matrixkomponenter i ledvätska och blod--ett nytt sät att studera broskpåverkan vid ledsjukdom.