Restriction site mapping of adenovirus types 9 and 15 and genome types of intermediate adenovirus 15/H9.
Physical maps were established for seven genome types of the intermediate adenovirus (AV) 15/H9 and for the serologically related prototypes AV15 and 9 using the enzymes BamHI, BglII, and HindIII. The polarity of the fragment order was determined by hybridization with known AV2 fragments. AV15/H9 strains showed more restriction sites in common with AV9 than with AV15. The results are consistent with the hypothesis that intermediate AV15/H9 strains have emerged by recombination.
Adrian
T
T
Department of Virology, University Hospital, Homburg Saar, FRG.
Bastian
B
B
Wagner
V
V
D000260:Adenoviruses, Human / Q000235:genetics*; D004279:DNA, Viral / Q000032:analysis; D005814:Genes, Viral; D009693:Nucleic Acid Hybridization; D011995:Recombination, Genetic; D015183:Restriction Mapping
D004279:DNA, Viral