Stabilization of phosphatidylethanolamine hydroperoxides in human plasma.
When phosphatidylcholine hydroperoxides (PC-OOH) and phosphatidylethanolamine hydroperoxides (PE-OOH) were incubated in normal saline at 37 degrees C, PE-OOH were decomposed more rapidly than PC-OOH, possibly due to Fe2+-binding ability of their polar head-group. In human plasma, both phospholipid hydroperoxides were stable during incubation. Iron ion-trapping ability of plasma components should be responsible for the hydroperoxide-stabilizing effect.
Terao
J
J
Research Institute for Food Science, Kyoto University, Japan.
D000328:Adult; D000818:Animals; D005296:Ferrous Compounds / Q000097:blood; D006801:Humans; D008054:Lipid Peroxides / Q000097:blood*; D008297:Male; D010713:Phosphatidylcholines / Q000097:blood; D010714:Phosphatidylethanolamines / Q000097:blood*; D051381:Rats; D011919:Rats, Inbred Strains
D005296:Ferrous Compounds; D008054:Lipid Peroxides; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines