[The effect of naloxone and delta-sleep inducing peptide on the homocarnosine content of brain tissue].
The intraventricular and intravenous administration of naloxone was studied for its effect on the homocarnosine amount in cerebral hemispheres, striatum, hippocamp, hypothalamus, thalamus, cerebellum, medulla oblongata as well as in the spinal cord of rabbits. The intracysternal administration of naloxone decreases the homocarnosine amount in the striatum, hypothalamus, cerebellum and medulla oblongata. The intravenous administration of peptide exerts no statistically reliable effect on the homocarnosine content in the rabbit brain. The intraperitoneal administration of delta-sleep-inducing peptide increases sharply the homocarnosine content in the rat brain.
Makletsova
M G
MG
Mendzheritskiĭ
A M
AM
Uskova
N I
NI
Choraian
I O
IO
Baĭich
M
M
D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects*; D002336:Carnosine / Q000031:analogs & derivatives / Q000378:metabolism*; D003701:Delta Sleep-Inducing Peptide / Q000494:pharmacology*; D004151:Dipeptides / Q000378:metabolism*; D009270:Naloxone / Q000494:pharmacology*; D011817:Rabbits; D051381:Rats; D013116:Spinal Cord / Q000187:drug effects / Q000378:metabolism
D004151:Dipeptides; C005038:homocarnosine; D009270:Naloxone; D003701:Delta Sleep-Inducing Peptide; D002336:Carnosine
Vliianie naloksona i del'ta-son-inutsiruiushchego peptida na soderzhaniie gomokarnozina v tkani golovnogo mozga.