title: Distribution of cross-bridges in isometrically contracting muscle: its deduction from the Huxley-Simmons theory and the effect of filament elasticity.
abstract: The author attempted to deduce a possible cross-bridge (XB) distribution as a function of x, the amount of stretch of the XB, by applying the Huxley-Simmons theory with their recent experimental data to a steady isometric contraction. I found no XB distribution which satisfied at once the Huxley-Simmons theory, their data and observations in muscle energetics and biochemistry. Further, a computation with a simple model suggested that the XB distribution could be broadened by the elasticity of the thick and/or the thin filament if it existed.
authors.affiliation: Department of Physiology, St. Marianna University School of Medicine, Kawasaki, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Tameyasu
mesh_terms: D004548:Elasticity; D007537:Isometric Contraction; D008954:Models, Biological; D009119:Muscle Contraction; D009124:Muscle Proteins / Q000502:physiology*
chemical_list: D009124:Muscle Proteins