Value of bilateral iliac crest needle biopsy for pretherapeutic tumor staging of bronchogenic carcinomas.
Two hundred and forty-three patients with lung cancer were biopsied pretherapeutically and bilaterally on the anterior iliac crest. Tumor infiltration into the bone marrow could be demonstrated in 7 patients. No tumor-positive biopsies were found in the 163 patients with non-small cell lung cancer (NSCLC). In small cell lung cancer (SCLC), however, the infiltration rate was 9% (7/80). In 3 of the 7 patients (43%) only 1 of the 2 sides biopsied had been infiltrated. All 7 patients with tumor-positive bone marrow samples were found to have additional metastases elsewhere (stage IV, 7/26; 27%). Therefore, according to our results, we cannot recommend iliac crest biopsy as a routine pretherapeutic procedure to aid in the staging of SCLC and NSCLC.
Manegold
C
C
Thoraxklinik der LVA Baden, Heidelberg-Rohrbach, BRD.
Krempien
B
B
Bülzebruck
H
H
Drings
P
P
D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000379:methods; D001856:Bone Marrow Examination / Q000379:methods*; D002283:Carcinoma, Bronchogenic / Q000473:pathology / Q000556:secondary*; D005260:Female; D006801:Humans; D007085:Ilium / Q000473:pathology*; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging