Fructose 2,6-bisphosphate and glucose 1,6-bisphosphate levels in erythrocytes with high and low 2,3-bisphosphoglycerate content during postnatal development.
In rabbit and sheep erythrocytes the concentrations of 2,3-bisphosphoglycerate, fructose 2,6-bisphosphate and glucose 1,6-bisphosphate suffer important changes after birth, which differ in both species. The changes of fructose 2,6-bisphosphate and glucose 1,6-bisphosphate correlate with the changes in the levels of the enzymatic activities involved in their synthesis. The change of 2,3-bisphosphoglycerate levels in rabbit but not in sheep erythrocytes could be explained by the changes of the phosphofructokinase/pyruvate kinase and 2,3-bisphosphoglycerate synthase/2,3-bisphosphoglycerate phosphatase activity ratios.
Gallego
C
C
Departament de Ciències Fisiològiques Humanes i de la Nutrició, Facultat de Medicina, Universitat de Barcelona, Zona Universitària de Pedralbes, Spain.
Carreras
J
J
D019794:2,3-Diphosphoglycerate; D000375:Aging / Q000097:blood; D000818:Animals; D000831:Animals, Newborn / Q000097:blood*; D004163:Diphosphoglyceric Acids / Q000097:blood*; D004912:Erythrocytes / Q000378:metabolism*; D005635:Fructosediphosphates / Q000097:blood*; D019298:Glucose-6-Phosphate / Q000031:analogs & derivatives*; D005958:Glucosephosphates / Q000097:blood*; D006019:Glycolysis; D006598:Hexosediphosphates / Q000097:blood*; D011817:Rabbits; D012756:Sheep; D013045:Species Specificity
D004163:Diphosphoglyceric Acids; D005635:Fructosediphosphates; D005958:Glucosephosphates; D006598:Hexosediphosphates; D019794:2,3-Diphosphoglycerate; D019298:Glucose-6-Phosphate; C027652:fructose 2,6-diphosphate; C016473:glucose-1,6-bisphosphate