title: [Clinical significance of cyclic nucleotide metabolism and calcium level in children with arrhythmia].
abstract: The cyclic nucleotides (CN) system and Ca2+ content were examined in children with various heart rhythm disorders (HRD). Marked changes were demonstrated which correlated to clinical manifestations of the arrhythmias: their type, phase, duration and favorable changes in their course. Antiarrhythmic therapy was associated with a normalization of the altered levels of cyclase components and Ca2+. The results suggest that intracellular metabolism regulation may be disrupted in HRD cases and play an important role in the development of arrhythmias.
authors.forename: T I
authors.initials: TI
authors.lastname: Ternova
authors.forename: M I
authors.initials: MI
authors.lastname: Bakanov
authors.forename: T V
authors.initials: TV
authors.lastname: Bershova
authors.forename: I L
authors.initials: IL
authors.lastname: Mikhaĭlova
authors.forename: N V
authors.initials: NV
authors.lastname: Danilova
mesh_terms: D000293:Adolescent; D001145:Arrhythmias, Cardiac / Q000097:blood* / Q000209:etiology; D002118:Calcium / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007962:Leukocytes / Q000378:metabolism*; D009712:Nucleotides, Cyclic / Q000097:blood*
chemical_list: D009712:Nucleotides, Cyclic; D002118:Calcium
vernacular_title: Klinicheskoe znachenie osobennosteĭ obmena tsiklicheskikh nukleotidov i soderzhaniia ka'ltsiia pri aritmiiakh serdtsa u deteĭ.