Gamete intrafallopian transfer (GIFT) as a complement to the tubal microsurgery.
We accomplished a transfer of at least one oocyte and sperms in 26 microsurgically operated patients. Two patients were stimulated by clomiphene citrate only, 24 women by a combination of a clomiphene citrate and human menopausal gonadotrophin. The operation was timed 34-36 hours after application of 6,000 IU hCG i.m. After finishing the surgery we transferred maximally two oocytes and 200,000 sperms to each patent tube. Using this procedure three pregnancies occurred (11.5%). However, there was one ongoing pregnancy only. The extrauterine pregnancy was successfully treated with methotrexat and the third pregnancy was biochemical. The number of clinical pregnancies in this modification doesn't reach the referred success rate of a standard gamete intrafallopian transfer.
Mardesić
T
T
Research Institute for the Care of the Mother and Child, Prague, Czechoslovakia.
Laitl
J
J
Uher
J
J
Jirásek
J E
JE
Stroufová
A
A
Presl
J
J
D000328:Adult; D003131:Combined Modality Therapy; D005187:Fallopian Tubes / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D015181:Gamete Intrafallopian Transfer; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D008866:Microsurgery; D011247:Pregnancy; D011274:Pregnancy, Tubal / Q000209:etiology; D012307:Risk Factors