Retrospective study of early postoperative convulsions after intracranial surgery with isoflurane or enflurane anaesthesia.
Retrospective analysis of the case records of 383 patients undergoing elective intracranial surgery showed that, in the first 24 h after surgery, 13.9% of patients receiving low concentrations (0.4-1 MAC) of isoflurane had one or more convulsions after operation, compared with 8% receiving enflurane (0.4-1 MAC). Controlled ventilation was required as part of the therapy for convulsions in 4.9% of the isoflurane group and 3.6% of the enflurane group. These differences between the groups were not statistically significant.
Christys
A R
AR
General Infirmary, Leeds.
Moss
E
E
Powell
D
D
D000769:Anesthesia, Inhalation / Q000009:adverse effects; D001921:Brain / Q000601:surgery*; D004737:Enflurane / Q000009:adverse effects; D006801:Humans; D007530:Isoflurane / Q000009:adverse effects; D011183:Postoperative Complications / Q000628:therapy; D012121:Respiration, Artificial; D012189:Retrospective Studies; D012640:Seizures / Q000209:etiology* / Q000628:therapy
D004737:Enflurane; D007530:Isoflurane