title: Does the rest electrocardiogram after myocardial infarction determine the predictive value of exercise-induced ST depression? A 2 year follow-up study in a veteran population.
abstract: The failure of exercise-induced ST segment depression to consistently predict prognosis in patients after myocardial infarction could be a result of population differences and the rest electrocardiogram (ECG). These hypotheses were tested by studying 198 veterans who survived a myocardial infarction, underwent a submaximal predischarge treadmill exercise test and were followed up for cardiac events for 2 years. During the 2 years, 29 deaths, 19 reinfarctions and 28 revascularization procedures were documented. The prevalence of death or reinfarction was two times higher in patients who had exercise-induced ST depression than in patients who did not. However, in the 55 patients without Q waves, the risk increased to 11 times for an abnormal ST response. These findings suggest that exercise-induced ST depression only predicts high risk in patients after myocardial infarction whose ECG at rest does not exhibit Q waves and that differences in the prevalence of rest ECG patterns are the most likely explanation for the failure of agreement among prior studies.
authors.affiliation: Cardiology Section, Long Beach Veterans Administration Medical Center, California 90822.
authors.forename: J
authors.initials: J
authors.lastname: Klein
authors.forename: V F
authors.initials: VF
authors.lastname: Froelicher
authors.forename: R
authors.initials: R
authors.lastname: Detrano
authors.forename: P
authors.initials: P
authors.lastname: Dubach
authors.forename: R
authors.initials: R
authors.lastname: Yen
mesh_terms: D004562:Electrocardiography; D005080:Exercise Test; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis*; D005082:Physical Exertion; D011379:Prognosis; D012307:Risk Factors; D013997:Time Factors