Biosynthesis of fusarochromanone and its monoacetyl derivative by Fusarium equiseti.
One fluorescent compound previously named TDP-2 was isolated and purified from a rice culture of Fusarium equiseti (Alaska 2-2). Mass spectral and nuclear magnetic resonance data indicated that it is a C-3'-N-acetyl derivative of fusarochromanone, a newly discovered mycotoxin. Time course studies of synthesis of these two compounds on autoclaved rice and Czapek-Dox medium enriched with soybean peptone indicated that fusarochromanone was converted to TDP-2 in the cultures. A high concentration of peptone in the liquid medium may stimulate both fusarochromanone synthesis and its conversion to TDP-2.
Xie
W P
WP
Department of Plant Pathology, University of Minnesota, St. Paul 55108.
Mirocha
C J
CJ
Pawlosky
R J
RJ
Wen
Y C
YC
Xu
X G
XG
D000596:Amino Acids / Q000096:biosynthesis* / Q000302:isolation & purification; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D002867:Chromones / Q000096:biosynthesis* / Q000302:isolation & purification; D003470:Culture Media; D005670:Fusarium / Q000254:growth & development / Q000378:metabolism*; D013058:Mass Spectrometry; D015394:Molecular Structure; D009183:Mycotoxins / Q000096:biosynthesis* / Q000302:isolation & purification; D012275:Oryza
D000596:Amino Acids; D002867:Chromones; D003470:Culture Media; D009183:Mycotoxins; C054523:fusarochromanone