title: Synthesis of myo-inositol derivatives required for the total synthesis of surugatoxin, prosurugatoxin, and neosurugatoxin.
abstract: Two myo-inositol derivatives (4) and (5), required for the total synthesis of surugatoxin, prosurugatoxin, and neosurugatoxin, were prepared. Synthesis of (+/-)-2,3-O-cyclohexylidene-4,5-O-isopropylidene-1-O-methoxymethyl-myo-i nositol (4) was achieved from (+/-)-1-O-benzoyl-2,3-O-cyclohexylidene-4,5-O-isopropylidene-myo-inosito l (6) in 4 steps, and (-)-2,3-O-cyclohexylidene-1,4-di-O-methoxymethyl-5-O-[2',3',4'-tri-O-ace tyl- beta-D-xylopyranosyl]-myo-inositol (5) was synthesized from (+/-)-1-O-benzoyl-2,3-O-cyclohexylidene-5,6-O-isopropylidene-myo-inosito l (12) in 7 steps.
authors.forename: K
authors.initials: K
authors.lastname: Okada
authors.forename: K
authors.initials: K
authors.lastname: Hashizume
authors.forename: H
authors.initials: H
authors.lastname: Tanino
authors.forename: H
authors.initials: H
authors.lastname: Kakoi
authors.forename: S
authors.initials: S
authors.lastname: Inoue
mesh_terms: D055598:Chemical Phenomena; D002621:Chemistry; D007294:Inositol / Q000138:chemical synthesis* / Q000494:pharmacology; D008978:Mollusk Venoms / Q000138:chemical synthesis*
chemical_list: D008978:Mollusk Venoms; C010340:surugatoxin; D007294:Inositol; C036793:neosurugatoxin; C047839:prosurugatoxin