title: [Significance of the clinical characteristics of manic, manic- paranoid and manic-hebephrenic conditions for differentiated psychopharmacotherapy].
abstract: In order to improve the treatment of 200 patients with endogenous psychoses, a total of 412 manic, manic paranoid and manic-hebephrenic exacerbations were studied as well as 1130 psychopharmacotherapeutic interventions. Two-factor dispersion analysis has revealed a substantial impact of such major clinical factors as the nature of treatment, nosology and course type, syndrome variant, and their interrelations on the treatment efficiency. The sum of the factors explained about 25% of variance of the therapy efficiency rating. The data provided a basis for a system of differentiated indications to use various treatments and the tables of their comparative efficiency developed which can serve as a practical guide for the practitioner in his choice of an adequate therapy.
authors.forename: S N
authors.initials: SN
authors.lastname: Mosolov
authors.forename: S G
authors.initials: SG
authors.lastname: Zaĭtsev
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001714:Bipolar Disorder / Q000175:diagnosis* / Q000188:drug therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010259:Paranoid Disorders / Q000175:diagnosis* / Q000188:drug therapy; D011619:Psychotropic Drugs / Q000627:therapeutic use*; D012562:Schizophrenia, Disorganized / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D011619:Psychotropic Drugs
vernacular_title: Znachenie klinicheskikh osobennosteĭ maniaka'lnykh, maniaka'lno-bredovykh i maniaka'lno-gebefrennykh sostoianiĭ dlia differentsirovannoĭ psikhofarmakoterapii.