Double minutes in two primary adenocarcinomas of the prostate.
Double minute chromosomes were found in metaphases from short-term tissue cultures of two primary prostatic adenocarcinomas. This is the first cytogenetic evidence of gene amplification in this tumor type.
Limon
J
J
Department of Clinical Genetics, University Hospital, Lund, Sweden.
Lundgren
R
R
Elfving
P
P
Heim
S
S
Kristoffersson
U
U
Mandahl
N
N
Mitelman
F
F
D000230:Adenocarcinoma / Q000235:genetics*; D000368:Aged; D002869:Chromosome Aberrations; D005784:Gene Amplification; D006801:Humans; D007621:Karyotyping; D008297:Male; D008677:Metaphase; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000235:genetics*