title: Antidepressant response in chronic major depression.
abstract: Treatment response to antidepressant medication was examined in 59 patients with nonchronic major depression and 35 patients with chronic major depression. Patients with chronic major depression had a poorer response to imipramine or desipramine than nonchronic patients.
authors.affiliation: Department of Psychiatry, Veterans Administration Medical Center, Iowa City, IA 52240.
authors.forename: M J
authors.initials: MJ
authors.lastname: Garvey
authors.forename: B L
authors.initials: BL
authors.lastname: Cook
authors.forename: G D
authors.initials: GD
authors.lastname: Tollefson
authors.forename: C B
authors.initials: CB
authors.lastname: Schaffer
mesh_terms: D000328:Adult; D000928:Antidepressive Agents / Q000627:therapeutic use*; D002908:Chronic Disease; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D003891:Desipramine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011581:Psychological Tests
chemical_list: D000928:Antidepressive Agents; D007099:Imipramine; D003891:Desipramine