Studies on the mechanism of action of Semecarpus anacardium in rheumatoid arthritis.
Semecarpus anacardium nuts are used for variety of disorders in Ayurveda. A chloroform extract of the nut significantly reduced acute carrageenan-induced paw oedema in rats and was active against the secondary lesions of adjuvant-induced arthritis. Delayed hypersensitivity induced in mice by sheep red blood cells as an antigen was potentiated by the extract.
Saraf
M N
MN
College of Pharmacy, Shreemati Nathibai Damodar Thakarsi Women's University, Bombay, India.
Ghooi
R B
RB
Patwardhan
B K
BK
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001169:Arthritis, Experimental / Q000188:drug therapy / Q000503:physiopathology; D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000503:physiopathology; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D006968:Hypersensitivity, Delayed / Q000503:physiopathology; D007194:India; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000627:therapeutic use*; D010946:Plants, Medicinal / Q000032:analysis*
D000893:Anti-Inflammatory Agents; D010936:Plant Extracts