title: [Genetic variants of the complement components and HLA-antigens associated in patients with psoriasis vulgaris in Japanese].
abstract: Genetic polymorphisms of the serum complement components (C2, C4, C6, and C7) and HLA-antigens were studied in Japanese patients with psoriasis vulgaris. Among these complement components, positive associations with C4A4 and C4B2 were obtained. In addition to the previously reported haplotypes HLA-Cw6-B13 and Cw6-Bw57-DR7, the extended haplotype HLA-Cw11-Bw46-C4A4. 4B2-BFS-C2C-DRw8 may be a high risk haplotype in Japanese patients with psoriasis vulgaris.
authors.forename: H
authors.initials: H
authors.lastname: Nakagawa
authors.forename: K
authors.initials: K
authors.lastname: Tokunaga
authors.forename: G
authors.initials: G
authors.lastname: Dewald
authors.forename: K
authors.initials: K
authors.lastname: Omoto
authors.forename: Y
authors.initials: Y
authors.lastname: Ishibashi
authors.forename: K
authors.initials: K
authors.lastname: Matsuki
authors.forename: T
authors.initials: T
authors.lastname: Juji
mesh_terms: D044466:Asian People; D003165:Complement System Proteins / Q000235:genetics*; D005260:Female; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D007564:Japan; D008297:Male; D011110:Polymorphism, Genetic; D011565:Psoriasis / Q000235:genetics*; D012306:Risk
chemical_list: D006680:HLA Antigens; D003165:Complement System Proteins