[Latent and postpartum thyroiditis. Prospective study].
Thyroid evaluation was performed in 85 women at childbirth, then between 2 and 7 months, and 14 months later. Transient subclinical hypothyroidism was found in one woman; antithyroid antibodies were found in 10 and were persistent in 6, suggesting a late thyroiditis. For these 6 cases, 5 HLA typing showed 3 Locus DR4. The proportion of antithyroid antibody was the same in a reference population. This finding would be in agreement with the hypothesis of a latent thyroiditis, revealed by pregnancy. Relative iodine deficiency in France could explain the low frequency of post partum thyroiditis in the present study.
Houdent
C
C
Service de Médecine Interne et Endocrinologie, CHU Rouen, Hôpital de Boisguillaume.
Turck
M F
MF
Basuyau
J P
JP
Delpech
A
A
Leclerc
P
P
Brunelle
P
P
Cavelier
B
B
Duval
C
C
Wolf
L M
LM
D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007037:Hypothyroidism / Q000276:immunology; D011247:Pregnancy; D011446:Prospective Studies; D011644:Puerperal Disorders / Q000276:immunology*; D013967:Thyroiditis, Autoimmune / Q000276:immunology*
Thyroïdite latente et post-partum. Etude prospective.