Antifertility effect of Bambusa arundinacea shoot extracts in male rats.
An ethanolic extract of Bambusa arundinacea tender shoots (BASE) caused a reduction in fertility of male rats. After administration of 300 mg/kg per day of BASE for 7 days, the fertility index decreased to 15% for control rats and to 23% after a 7-day recovery period, respectively. The number of cohabited females being successfully inseminated was reduced especially after 4 days of treatment. Complete recovery of mating behaviour was evident 8 days after BASE withdrawal. The number of spermatozoa in the caput and cauda epididymis were decreased concomitant with a decrease in the motility of spermatozoa collected from the cauda epididymis. The weights of testes, epididymides, vas deferens and prostate were also significantly decreased. The serum profile of protein and oxaloacetic/pyruvic transaminase activity show the extract to be relatively non-toxic.
Vanithakumari
G
G
Department of Endocrinology, Postgraduate Institute of Basic Medical Sciences, Madras, India.
Manonayagi
S
S
Padma
S
S
Malini
T
T
D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001798:Blood Proteins / Q000378:metabolism; D003276:Contraceptives, Oral; D004822:Epididymis / Q000166:cytology / Q000187:drug effects; D005298:Fertility / Q000187:drug effects; D007668:Kidney / Q000187:drug effects; D008099:Liver / Q000187:drug effects; D008297:Male; D009929:Organ Size / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D013081:Sperm Motility / Q000187:drug effects; D013094:Spermatozoa / Q000187:drug effects
D001798:Blood Proteins; D003276:Contraceptives, Oral; D010936:Plant Extracts; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase