In vitro flow measurements in ion sputtered hydrocephalus shunts.
Accurate in vitro measurements of the pressure drop-flow (drainage) rate relationship were made for perforated Teflon microtubules using a fish hook arrangement. These measurements indicated that appropriate drainage rates could be obtained in the physiological range for hydrocephalus shunts. Animal experimentation is required for in vivo evaluation of these microtubules with micron-sized holes that may prevent cellular ingrowth and recurrent obstruction, and thus extend implanted shunt life.
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Jet Propulsion Laboratory, California Institute of Technology, Pasadena 91109.
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D000818:Animals; D002555:Cerebrospinal Fluid / Q000502:physiology*; D015170:Cerebrospinal Fluid Pressure; D002557:Cerebrospinal Fluid Shunts / Q000379:methods*; D006801:Humans; D006849:Hydrocephalus / Q000503:physiopathology* / Q000601:surgery; D008962:Models, Theoretical; D012212:Rheology; D014783:Viscosity