Antimicrobial susceptibilities of Streptococcus species that cause septicemia in neutropenic patients.
Sixty-three consecutive streptococcal blood isolates from neutropenic patients, represented mainly by viridans group streptococci, were evaluated in vitro for antibiotic susceptibility. Of these isolates, 79.3% were highly susceptible to penicillin (MIC, less than or equal to 0.12 microgram/ml). Overall, imipenem was the most active agent, followed by teicoplanin and vancomycin. All other agents showed decreased activity against streptococcal isolates that were not highly susceptible to penicillin.
Venditti
M
M
Cattedra di Patologia Medica III, Università La Sapienza, Rome, Italy.
Baiocchi
P
P
Santini
C
C
Brandimarte
C
C
Serra
P
P
Gentile
G
G
Girmenia
C
C
Martino
P
P
D000380:Agranulocytosis / Q000150:complications*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D009503:Neutropenia / Q000150:complications*; D018805:Sepsis / Q000209:etiology / Q000382:microbiology*; D013291:Streptococcus / Q000187:drug effects*
D000900:Anti-Bacterial Agents