Tumour necrosis factor in neonatal listeriosis: a case report.
A newborn with fatal neonatal listeriosis developed septic shock, neutropenia, thrombocytopenia and profound hypoxaemia due to severe pulmonary hypertension. Tumour necrosis factor alpha, interleukin-1-beta and interferon-gamma serum concentrations were markedly elevated, suggesting the participation of these cytokines in the aetiopathogenesis of shock induced by Listeria monocytogenes in the neonate.
Girardin
E
E
Department of Paediatrics and Genetics, Hôpital Cantonal Universitaire de Genève, Switzerland.
Berner
M
M
Grau
G E
GE
Dayer
J M
JM
Roux-Lombard
P
P
Suter
S
S
D000658:Amoxicillin / Q000627:therapeutic use; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology; D007231:Infant, Newborn; D008088:Listeriosis / Q000097:blood* / Q000150:complications; D008297:Male; D012772:Shock, Septic / Q000209:etiology*; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis*
D005839:Gentamicins; D014409:Tumor Necrosis Factor-alpha; D000658:Amoxicillin