title: Viral and Mycoplasma pneumoniae pneumonias in school-age children: three-year follow-up of respiratory function.
abstract: We studied the evolution of respiratory function during and for 3 years after the acute onset of viral and Mycoplasma pneumoniae pneumonias in 13 school-age children. A mixed type transient ventilatory defect (restrictive and obstructive, but mainly restrictive) with large and small airway involvement was observed during the acute phase of the pneumonias. Residual small airway involvement was found over the next 12 months, but no pulmonary function abnormalities were present after 3 years. At that time, one of the 13 subjects displayed bronchial hyperreactivity to distilled water mist challenge. The authors concluded that viral and Mycoplasma pneumoniae pneumonia in previously healthy school-age children does not cause impaired lung function in later childhood.
authors.affiliation: Cattedra di Fisiopatologia Respiratoria, University of Perugia, Italy.
authors.forename: T
authors.initials: T
authors.lastname: Todisco
authors.forename: F M
authors.initials: FM
authors.lastname: de Benedictis
authors.forename: M
authors.initials: M
authors.lastname: Dottorini
mesh_terms: D000258:Adenovirus Infections, Human / Q000503:physiopathology; D000293:Adolescent; D000402:Airway Obstruction / Q000503:physiopathology; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007251:Influenza, Human / Q000503:physiopathology; D008176:Lung Volume Measurements; D008297:Male; D011019:Pneumonia, Mycoplasma / Q000503:physiopathology*; D011024:Pneumonia, Viral / Q000503:physiopathology*; D011446:Prospective Studies; D012123:Pulmonary Ventilation; D010253:Respirovirus Infections / Q000503:physiopathology