[Clinical experience of autotransfusion system (ATS)--changes in free hemoglobin and haptoglobin].
This study was done to evaluate the usefulness of ATS and the administration of haptoglobin, and is comprised of 15 patients following open heart surgery. Shed mediastinal blood was retransfused during 4-6 hours after open heart surgery. Plasma free Hb (F-Hb) value of the shed blood was 647 mg/dl. But plasma F-Hb of patient did not significantly increase after retransfusion of shed blood without administration of haptoglobin. Plasma F-Hb of patient decreased significantly from 12 mg/dl to 3.3 mg/dl when haptoglobin was given. (p less than 0.05). There was no serious complication associated with the use of ATS, and could save 300 ml of homologous blood. It is concluded that ATS can be used safely for saving homologous blood after open heart surgery and haptoglobin is effective for decreasing of plasma F-Hb.
Nagamine
S
S
Tabayashi
K
K
Yamaki
S
S
Haneda
K
K
Suzuki
Y
Y
Mohri
H
H
D001804:Blood Transfusion, Autologous / Q000295:instrumentation*; D005069:Evaluation Studies as Topic; D005260:Female; D006242:Haptoglobins / Q000008:administration & dosage / Q000032:analysis*; D006331:Heart Diseases / Q000601:surgery; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged
D006242:Haptoglobins; D006454:Hemoglobins