title: Effects of thyroid hormones on cartilage sulphation in sex-linked dwarf chickens.
abstract: The present investigation was undertaken to see if exogenous thyroid hormome could stimulate cartilage sulphation in vivo and in vitro in sex-linked dwaft chickens B-thyroxine or 1-3,5,5-triiodothyronine injection for 7 consecutive days stimulated in vivo 35SO2-4 incorporation into trachea cartilages of the dwarf chicken. Both thyroid hormones added to the incubation medium with or without 2.5% dwarf chicken serum also stimulated in vitro 35SO2-4 incorporation into pelvic rudiment from 11-day chick embryos. These data demonstrate that thyroid hormones, like insulin-like growth factor 1, might be responsible for the reduced growth rate of dwarf chickens.
authors.affiliation: Faculty of Bioresources, Mie University, Tsu, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Hoshino
authors.forename: M
authors.initials: M
authors.lastname: Wakita
authors.forename: Y
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: T
authors.initials: T
authors.lastname: Kakegawa
authors.forename: M
authors.initials: M
authors.lastname: Suzuki
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002356:Cartilage / Q000378:metabolism*; D002642:Chick Embryo; D002645:Chickens; D004392:Dwarfism / Q000378:metabolism*; D005260:Female; D008297:Male; D013431:Sulfates / Q000378:metabolism*; D013974:Thyroxine / Q000008:administration & dosage*; D014284:Triiodothyronine / Q000008:administration & dosage*
chemical_list: D013431:Sulfates; D014284:Triiodothyronine; D013974:Thyroxine