title: Severe Silver-Russell syndrome.
abstract: Three children are described with severe Silver-Russell syndrome. Major medical problems occurred in the first two years of life in all three. Silver-Russell syndrome should be considered in the differential diagnosis of children with severe pre- and postnatal growth deficiency.
authors.affiliation: Regional Genetic Service, St Mary's Hospital, Manchester.
authors.forename: D
authors.initials: D
authors.lastname: Donnai
authors.forename: E
authors.initials: E
authors.lastname: Thompson
authors.forename: J
authors.initials: J
authors.lastname: Allanson
authors.forename: M
authors.initials: M
authors.lastname: Baraitser
mesh_terms: D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D005317:Fetal Growth Retardation; D005532:Foot Deformities, Congenital / Q000150:complications; D006130:Growth Disorders / Q000150:complications / Q000175:diagnosis*; D006257:Head / Q000002:abnormalities; D006801:Humans; D007223:Infant; D008297:Male; D011247:Pregnancy; D013577:Syndrome