[A case of radiation-induced intracranial fibrosarcoma with repeated episodes of intratumoral hemorrhage].
A fibrosarcoma developed 10 years after radiotherapy for craniopharyngioma in a 19-year-old girl is reported. The mode of presentation in this patient was unique. She had repeated episodes of intracranial bleeding which mimicked hemorrhagic cerebral infarction, and there was also an extremely rapid regrowth of the tumor after each resection. Chemotherapy with ACNU, cisplatin and adriamycin was transiently effective in the stormy course of this patient. The occurrence of radiation induced intracranial tumor should be kept in mind in the follow up study of patients with benign brain tumors who have received radiation therapy.
Yamamoto
A
A
Department of Neurosurgery, Kyoto University.
Hashimoto
N
N
Yamashita
J
J
Kikuchi
H
H
D000328:Adult; D001932:Brain Neoplasms / Q000209:etiology* / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000473:pathology*; D003397:Craniopharyngioma / Q000532:radiotherapy; D005260:Female; D005354:Fibrosarcoma / Q000209:etiology* / Q000473:pathology; D006801:Humans; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D010911:Pituitary Neoplasms / Q000532:radiotherapy; D011878:Radiotherapy / Q000009:adverse effects*