Virulence studies based on plasmid profiles of the fish pathogen Vibrio salmonicida.
Strains of Vibrio salmonicida isolated from Atlantic salmon (Salmo salar) and rainbow trout (Salmo gairdneri) suffering from cold-water vibriosis could be divided on the basis of plasmid profiles into four different categories. Of 32 strains, 19% harbored three plasmids of 24, 3.4, and 26 megadaltons (MDa), 69% harbored the 24- and 3.4-MDa plasmids but not the 2.6-MDA plasmid, and 9% harbored only the 24-MDA plasmid. The fourth category, which consisted of only one strain, harbored a plasmid of 10 MDa. In spite of different plasmid patterns, the strains of V. salmonicida were very similar with respect to biochemical reactions. The one-third of the V. salmonicida strains which were serotyped were of the same type. The 50% lethal doses, which were determined by intraperitoneal injection, ranged from 4 x 106 to 1 x 108 CFU per fish.
Wiik
R
R
Department of Microbiology and Plant Physiology, University of Bergen, Norway.
Andersen
K
K
Daae
F L
FL
Hoff
K A
KA
D000818:Animals; D005393:Fish Diseases / Q000382:microbiology*; D010957:Plasmids; D015183:Restriction Mapping; D012474:Salmon; D012487:Salmonidae; D014337:Trout; D014733:Vibrio / Q000235:genetics* / Q000472:pathogenicity; D014735:Vibrio Infections / Q000382:microbiology / Q000662:veterinary*; D014774:Virulence