Humoral immune responses in dapsone treated M. leprae infected mice.
Humoral responses in M. leprae infected mice were studied through 52 weeks and were found to be directly related to the bacterial load. However, treatment with dapsone (DDS) in the last 12 weeks of infection resulted in an initial enhancement of the humoral responses followed by a gradual decrease, though they were still significantly high at the end of the study.
Srinivasan
R
R
Dept. of Pediatrics, Cornell Medical Centre, New York, NY 10021.
Rao
P R
PR
D000818:Animals; D000917:Antibody Formation; D003622:Dapsone / Q000097:blood / Q000276:immunology* / Q000627:therapeutic use; D007074:Immunoglobulin G / Q000032:analysis; D007918:Leprosy / Q000097:blood / Q000188:drug therapy / Q000276:immunology*; D051379:Mice
D007074:Immunoglobulin G; D003622:Dapsone