Familial analysis of bipolar affective disorder using logistic models.
Data on bipolar affective disorder in 187 pedigrees from the Collaborative Depression Study were analyzed using logistic models that have been extended to incorporate age of onset information. Logistic regression analysis and segregation analysis revealed evidence for complex familial effects on this disorder.
Blangero
J
J
Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78284.
Elston
R C
RC
D000367:Age Factors; D001714:Bipolar Disorder / Q000235:genetics*; D015331:Cohort Studies; D006801:Humans; D008957:Models, Genetic; D012044:Regression Analysis