Development of severe Stevens-Johnson syndrome after administration of slow-release theophylline.
A 9-year-old boy developed Stevens-Johnson syndrome after taking slow-release theophylline for bronchial asthma. Multisystem symptoms were severe, especially in the skin and eyes. This is the first reported case of Stevens-Johnson syndrome after administration of theophylline (Theodur).
Brook
U
U
Department of Pediatrics, Sackler Faculty of Medicine, Tel-Aviv University, Israel.
Singer
L
L
Fried
D
D
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy; D002648:Child; D003231:Conjunctivitis / Q000139:chemically induced / Q000628:therapy; D003692:Delayed-Action Preparations; D006801:Humans; D008297:Male; D011379:Prognosis; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced* / Q000188:drug therapy; D013806:Theophylline / Q000008:administration & dosage / Q000009:adverse effects*
D000900:Anti-Bacterial Agents; D003692:Delayed-Action Preparations; D013806:Theophylline