Merkel cell tumor of the eyelid: a review and report of an unusual case.
We describe a case of a Merkel cell tumor of the eyelid that manifested as a recurrent chalazion. This tumor had the classic characteristics of a Merkel cell neoplasm by light microscopy. Electron microscopy showed dense-core neurosecretory granules and perinuclear microfilaments consistent with the diagnosis. Because a Merkel cell tumor may manifest as a chalazion, pathologic evaluation of all atypical chalazia is essential. Merkel cell tumors are malignant, and they must be treated aggressively to minimize recurrence or metastasis.
Mamalis
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N
Department of Ophthalmology, University of Utah School of Medicine, Salt Lake City.
Medlock
R D
RD
Holds
J B
JB
Anderson
R L
RL
Crandall
A S
AS
D000368:Aged; D001706:Biopsy; D015266:Carcinoma, Merkel Cell / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D005122:Exudates and Transudates / Q000378:metabolism; D005142:Eyelid Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D008297:Male