title: Methylphenidate in amytal-resistant mutism.
abstract: Methylphenidate eliminated mutism in a catatonic schizophrenic after Amytal had failed. Response permitted an adequate clinical evaluation and temporary resumption of eating, self-care and sociability. This suggests that methylphenidate has a useful role in the clinical evaluation of the mute patient who fails to respond to Amytal and that 2 psychopharmacological varieties of catatonic mutism may exist.
authors.affiliation: Department of Psychiatry, Montreal General Hospital, Quebec, Canada.
authors.forename: L H
authors.initials: LH
authors.lastname: Frost
mesh_terms: D000328:Adult; D000654:Amobarbital / Q000627:therapeutic use*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008774:Methylphenidate / Q000627:therapeutic use*; D009155:Mutism / Q000188:drug therapy* / Q000523:psychology; D012560:Schizophrenia, Catatonic / Q000188:drug therapy / Q000523:psychology
chemical_list: D008774:Methylphenidate; D000654:Amobarbital