title: Adhesiveness and invasiveness of staphylococcal species in a cell culture model.
abstract: A model was established for the study of adhesiveness and invasiveness of staphylococcal species. Five collection strains from each of the species Staphylococcus aureus, S. epidermidis, and S. saprophyticus and 26 fresh isolates from patients with urinary tract infections were tested for adhesiveness and invasiveness in HEp-2 cell cultures. All the strains of S. saprophyticus were able to invade the cells and localize intracellularly in the cultures, whereas the invasive potential among the strains of S. aureus and S. epidermidis was lower. The number of adhesive bacteria was also highest among the S. saprophyticus strains, whereas S. epidermidis was the least adhesive. The model may be suitable for further study of urinary tract infection strains.
authors.affiliation: Institute of Microbiology, Wilhelm-Pieck University of Rostock, GDR.
authors.forename: H
authors.initials: H
authors.lastname: Schmidt
authors.forename: G
authors.initials: G
authors.lastname: Bukholm
authors.forename: M
authors.initials: M
authors.lastname: Holberg-Petersen
mesh_terms: D001422:Bacterial Adhesion; D002460:Cell Line; D006801:Humans; D066298:In Vitro Techniques; D013210:Staphylococcus / Q000166:cytology / Q000472:pathogenicity*