title: Thrombocytopenia--a rare but potentially serious side effect of initial daily and interrupted use of rifampicin.
abstract: Thrombocytopenia is occasionally caused by rifampicin, when high-doses are given twice-weekly. This complication is rare when the medication is given in small daily doses, or following a prolonged interruption of therapy. Two cases of rifampicin-induced thrombocytopenia are reported. One occurred within four days of the initiation of small daily doses and the other following a prolonged interruption of therapy.
authors.affiliation: Department of Chest Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China.
authors.forename: C H
authors.initials: CH
authors.lastname: Lee
authors.forename: C J
authors.initials: CJ
authors.lastname: Lee
mesh_terms: D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012293:Rifampin / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D013921:Thrombocytopenia / Q000139:chemically induced*; D013997:Time Factors; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy
chemical_list: D012293:Rifampin