title: Therapeutic value of citicoline in the treatment of glaucoma (computerized and automated perimetric investigation).
abstract: The favourable neurotrophic effects obtained by means of the intramuscular administration of citicoline, one of the intermediate compounds of phospholipids, on the visual field of patients suffering from open-angle glaucoma are referred. The drug was administered at the dose of 1 gm for ten consecutive days. Visual field was examined by means of central computerized perimetry and automated perimetry. All patients had well controlled intraocular pressure through beta-blockers, but presented characteristic glaucomatous perimetric defects. It is suggested that citicoline might be administered as a useful complement to conventional hypotensive therapy, since it acts positively on the glaucomatous optic nerve damage.
authors.affiliation: Clinica Oculistica I, Universita Di Roma La Sapienza, Italia.
authors.forename: J
authors.initials: J
authors.lastname: Pecori Giraldi
authors.forename: M
authors.initials: M
authors.lastname: Virno
authors.forename: G
authors.initials: G
authors.lastname: Covelli
authors.forename: G
authors.initials: G
authors.lastname: Grechi
authors.forename: F
authors.initials: F
authors.lastname: De Gregorio
mesh_terms: D000328:Adult; D000368:Aged; D002794:Choline / Q000031:analogs & derivatives*; D003566:Cytidine Diphosphate Choline / Q000494:pharmacology*; D005902:Glaucoma, Open-Angle / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D012607:Scotoma / Q000150:complications; D013997:Time Factors; D058609:Visual Field Tests; D014794:Visual Fields / Q000187:drug effects*
chemical_list: D003566:Cytidine Diphosphate Choline; D002794:Choline