[Preoperative topical antibiotics in patients subjected to short term prophylaxis for colorectal surgery].
In spite of the widespread use of antibiotics wound infection are still a common complication of elective colon and rectal surgery. Oral administration of poorly absorbed antibiotics was for a long time a common practice in preparing patients for elective clo-rectal operations. Systemic antibiotic prophylaxis allowed a significant improvement of septic complication rate. As the clinical effectiveness of the combined antibiotic regimen is still not completely demonstrated, we carried out a study on 165 patients who underwent colo-rectal surgery. A group of 63 patients submitted to short term prophylaxis with Clindamycin and Gentamycin was compared with a 102 patients group who received preoperative topic antibiotics (Neomycin and Metronidazole) plus short term prophylaxis. The two groups did not show a statistically significative incidence of wound infections (6.3% vs 3.9%; p greater than 0.05).
Di Palo
S
S
Ferrari
G
G
Castoldi
R
R
Di Carlo
V
V
D000287:Administration, Topical; D000368:Aged; D003108:Colonic Diseases / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D009355:Neomycin / Q000627:therapeutic use*; D011292:Premedication; D012002:Rectal Diseases / Q000601:surgery; D013530:Surgical Wound Infection / Q000517:prevention & control*
D008795:Metronidazole; D009355:Neomycin
Antibiosi topica preoperatoria nei pazienti sottoposti a short term prophylaxis per chirurgia colorettale.