title: [Effect of splenin and splenic protein-free extracts on the adenosine deaminase activity in various organs of the rat].
abstract: It has been shown that the adenosine deaminase activity of intact rats increases in such lymphoid organs as the thymus and spleen under the influence of splenic protein-free extracts dissolved in the ratio of 1:100. The enzyme activity in testes does not change but its decrease (by 26.2%) is observed in the adrenal glands under the influence of the splenic protein-free extract. An analogous effect is revealed in splenin and its fractions. The splenic protein-free extract increases (by 83%) the enzyme activity in the thymus of splenectomized rats as compared to intact animals but does not change it in a homogenate of testes.
authors.forename: V V
authors.initials: VV
authors.lastname: Korpachev
authors.forename: E A
authors.initials: EA
authors.lastname: Litvinenko
mesh_terms: D000243:Adenosine Deaminase / Q000378:metabolism*; D000311:Adrenal Glands / Q000187:drug effects / Q000201:enzymology; D000818:Animals; D008297:Male; D009700:Nucleoside Deaminases / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000187:drug effects / Q000201:enzymology; D013737:Testis / Q000187:drug effects / Q000201:enzymology; D013946:Thymopoietins / Q000494:pharmacology*; D013950:Thymus Gland / Q000187:drug effects / Q000201:enzymology; D013951:Thymus Hormones / Q000494:pharmacology*; D014020:Tissue Extracts / Q000494:pharmacology*
chemical_list: D013946:Thymopoietins; D013951:Thymus Hormones; D014020:Tissue Extracts; C032841:thymopoietin III; D009700:Nucleoside Deaminases; D000243:Adenosine Deaminase
vernacular_title: Vliianie splenina i bezbelkovogo ékstrakta selezenki na adenozindezaminaznuiu aktivnost' nekotorykh organov krys.