title: Experimental allergic encephalomyelitis. I. Oligodendroglial cell population in monkey brain at the acute stage.
abstract: Populations of oligodendroglial cells (ODC) visualized by the neuroglial impregnation technique were investigated in demyelinated (A), actively demyelinating (B) and non-demyelinating (C) zones in both the cerebral and cerebellar white matter of monkeys with active EAE lesions. A marked reduction of the ODC population (P less than 0.001) was recognized not only in zones A and B but also in zone C as compared with those of non-sensitized monkeys. This suggests that the injury seen in ODC precedes myelin sheath destruction.
authors.affiliation: Department of Pathology, National Institute of Health, Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ohkawa
mesh_terms: D000208:Acute Disease; D000818:Animals; D001921:Brain / Q000473:pathology; D002452:Cell Count; D003711:Demyelinating Diseases / Q000473:pathology; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000473:pathology*; D008251:Macaca; D009457:Neuroglia / Q000473:pathology*; D009836:Oligodendroglia / Q000473:pathology*