[Morphotypes of serum crystallograms and various indices of glycoprotein metabolism in patients with toxic goiter].
Crystallographic investigation of the blood serum of 65 patients and 20 healthy persons aged 20 to 45 was conducted to observe the content of carbohydrate components of glycoproteins in toxic goiter over time and to study the content of seromucoid and sialic acids. Crystallograms were obtained by placing a drop of blood serum between two isotropic plates and dried under controlled conditions for 12 h. The obtained specimen was investigated microscopically in transmitted and polarized light. N-acetylneuraminic acid was used. The data obtained indicated the heterogeneity of micromorphotypes of crystallograms of patients with toxic goiter which formed individual macromorphotypes according to the gravity of disease. Crystallography of the blood serum can be used as an adjuvant method to control glycoprotein metabolic derangements and as a diagnostic method for toxic goiter.
Savina
L V
LV
Timofeeva
L A
LA
D000328:Adult; D003461:Crystallography; D005260:Female; D006023:Glycoproteins / Q000097:blood*; D006042:Goiter / Q000097:blood*; D006801:Humans; D008875:Middle Aged; D009961:Orosomucoid / Q000378:metabolism; D012794:Sialic Acids / Q000097:blood
D006023:Glycoproteins; D009961:Orosomucoid; D012794:Sialic Acids
Morfotipy kristallogramm syvorotki krovi i nekotorye pokazateli glikoproteidonogo obmena u bol'nykh toksicheskim zobom.