The role of aldehyde dehydrogenase isozymes in cellular resistance to the alkylating agent cyclophosphamide.
Russo
J E
JE
Johns Hopkins Oncology Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.
Hilton
J
J
Colvin
O M
OM
D000444:Aldehyde Dehydrogenase / Q000378:metabolism*; D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D003520:Cyclophosphamide / Q000494:pharmacology*; D003600:Cytosol / Q000201:enzymology; D004351:Drug Resistance; D007527:Isoenzymes / Q000378:metabolism*; D007583:Jejunum / Q000166:cytology / Q000201:enzymology*; D007700:Kinetics; D007939:Leukemia L1210 / Q000201:enzymology*; D051379:Mice; D013379:Substrate Specificity; D014407:Tumor Cells, Cultured / Q000187:drug effects / Q000201:enzymology
D007527:Isoenzymes; D003520:Cyclophosphamide; D000444:Aldehyde Dehydrogenase