title: Comparison of the effect of atropine and cyclopentolate on myopia.
abstract: We evaluated the effectiveness of cycloplegics in the treatment of myopia. Patients were selected randomly and divided into three groups: Group 1 received atropine 1% eye drops every other night; Group 2 received cyclopentolate 1% eye drops every night; and Group 3 received normal saline eye drops every night. All the patients were rechecked every three months. The results were evaluated at the end of one year. Ninety-six patients were evaluated, 32 in each group. The mean myopic progression was -0.219 D in the atropine group, -0.578D in the cyclopentolate group, and -0.914D in the saline group. Analysis showed that atropine and cyclopentolate are effective in slowing the progression of myopia. The effect of atropine is better than that of cyclopentolate.
authors.affiliation: Department of Ophthalmology, Veterans General Hospital, Yang-Ming Medical College, Taipei, Taiwan, Republic of China.
authors.forename: M Y
authors.initials: MY
authors.lastname: Yen
authors.forename: J H
authors.initials: JH
authors.lastname: Liu
authors.forename: S C
authors.initials: SC
authors.lastname: Kao
authors.forename: C H
authors.initials: CH
authors.lastname: Shiao
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D001285:Atropine / Q000627:therapeutic use*; D002648:Child; D003519:Cyclopentolate / Q000627:therapeutic use*; D004341:Drug Evaluation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009216:Myopia / Q000188:drug therapy*; D010648:Phenylacetates / Q000627:therapeutic use*; D011897:Random Allocation; D012030:Refractive Errors / Q000188:drug therapy; D013997:Time Factors
chemical_list: D010648:Phenylacetates; D001285:Atropine; D003519:Cyclopentolate