[Natural killer activity of the splenocytes in C3HA strain mice during 20-methylcholanthrene-induced carcinogenesis].
The induction of tumor in C3HA mice after intramuscular injection with 20-methylcholanthrene is accompanied by a decrease in natural antitumor resistance. This conclusion is based on the observation of the decreased natural killer activity per total number of splenocytes, from the time of carcinogen application till the appearance of tumor nodes.
Pogodina
O N
ON
Malygin
A M
AM
Goriunova
L B
LB
Fel'
V Ia
VIa
D000818:Animals; D002452:Cell Count / Q000187:drug effects; D003602:Cytotoxicity, Immunologic / Q000187:drug effects; D007694:Killer Cells, Natural / Q000187:drug effects* / Q000276:immunology; D008297:Male; D008748:Methylcholanthrene / Q000633:toxicity*; D051379:Mice; D008809:Mice, Inbred C3H / Q000276:immunology*; D009374:Neoplasms, Experimental / Q000139:chemically induced* / Q000276:immunology; D009929:Organ Size / Q000187:drug effects; D013154:Spleen / Q000187:drug effects* / Q000276:immunology; D013997:Time Factors
D008748:Methylcholanthrene
Estestvennaia killernaia aktivnost' splenotsitov mysheĭ linii C3HA v usloviiakh kantserogeneza, vyzvannogo 20-metilkholantrenom.