The hypo-osmotic swelling test and the sperm mucus penetration test in determining fertilization of the human oocyte.
The usefulness of the hypo-osmotic swelling (HOS) test and the sperm mucus penetration (SMP) test as sperm function tests for in-vitro fertilization was analysed in 56 couples. Using logistic regression analysis only the SMP test was independently related to fertilization (P = 0.004), no false negative results were obtained, i.e. no fertilization if sperm from the ejaculate failed to penetrate mucus. The HOS test was of no predictive value. The results justify a further examination of the SMP test in other IVF centres.
Barratt
C L
CL
Harris Birthright Centre for Reproductive Medicine, Department of Obstetrics and Gynaecology, University of Sheffield, Jessop Hospital for Women, UK.
Osborn
J C
JC
Harrison
P E
PE
Monks
N
N
Dunphy
B C
BC
Lenton
E A
EA
Cooke
I D
ID
D002582:Cervix Mucus; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008297:Male; D009865:Oocytes / Q000502:physiology*; D009994:Osmolar Concentration; D009997:Osmotic Pressure; D013094:Spermatozoa / Q000502:physiology*