title: Chemotherapy of caecal coccidiosis: efficacy of toltrazuril, sulphaquinoxaline/pyrimethamine and amprolium/ethopabate, given in drinking water, against field isolates of Eimeria tenella.
abstract: Treatment with toltrazuril, sulphaquinoxaline/pyrimethamine and amprolium/ethopabate prevented mortality in chickens infected with field isolates of Eimeria tenella. Amprolium/ethopabate was the most effective drug in reducing lesions caused by the parasites. Few oocysts of E tenella were produced in birds medicated with sulphaquinoxaline/pyrimethamine or amprolium/ethopabate and none in those medicated with toltrazuril.
authors.affiliation: Institute for Animal Health, Houghton Laboratory, Huntingdon, Cambridgeshire.
authors.forename: H D
authors.initials: HD
authors.lastname: Chapman
mesh_terms: D000284:Administration, Oral; D000670:Amprolium / Q000008:administration & dosage / Q000627:therapeutic use; D000818:Animals; D002429:Cecal Diseases / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D002645:Chickens / Q000469:parasitology*; D003048:Coccidiosis / Q000188:drug therapy / Q000662:veterinary*; D003049:Coccidiostats / Q000008:administration & dosage / Q000627:therapeutic use*; D004338:Drug Combinations; D004341:Drug Evaluation; D005011:Ethopabate / Q000008:administration & dosage / Q000627:therapeutic use; D011201:Poultry Diseases / Q000188:drug therapy* / Q000469:parasitology; D011739:Pyrimethamine / Q000008:administration & dosage / Q000627:therapeutic use*; D013424:Sulfanilamides / Q000627:therapeutic use*; D013428:Sulfaquinoxaline / Q000008:administration & dosage / Q000627:therapeutic use*; D014227:Triazines / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D003049:Coccidiostats; D004338:Drug Combinations; D013424:Sulfanilamides; D014227:Triazines; D005011:Ethopabate; D000670:Amprolium; C036670:toltrazuril; D013428:Sulfaquinoxaline; D011739:Pyrimethamine