title: Mitotic arrest induced by fenvalerate in human lymphocyte cultures.
abstract: The pyrethroid insecticide fenvalerate was tested for its ability to induce C-mitosis in cultured human peripheral blood lymphocytes at concentrations ranging from 2-50 micrograms/ml. We observed a significant increase in C-mitotic figures, indicating that this compound was effective in producing disturbance of spindle function.
authors.affiliation: Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Carbonell
authors.forename: M
authors.initials: M
authors.lastname: Puig
authors.forename: N
authors.initials: N
authors.lastname: Xamena
authors.forename: A
authors.initials: A
authors.lastname: Creus
authors.forename: R
authors.initials: R
authors.lastname: Marcos
mesh_terms: D002478:Cells, Cultured; D006801:Humans; D007306:Insecticides / Q000633:toxicity*; D008214:Lymphocytes / Q000187:drug effects*; D008938:Mitosis / Q000187:drug effects*; D009570:Nitriles; D011722:Pyrethrins / Q000633:toxicity*
chemical_list: D007306:Insecticides; D009570:Nitriles; D011722:Pyrethrins; C017690:fenvalerate