Erythema chronicum migrans as the presenting manifestation of juvenile chronic myelocytic leukemia.
We describe the case of a 3-year-old boy who presented with typical clinical features of Lyme disease, including erythema chronicum migrans and arthritis. Over subsequent months, however, the clinical picture evolved into juvenile chronic myelocytic leukemia. To our knowledge, the combination of Lyme disease and juvenile chronic myelocytic leukemia has not been described. Dermatologic and other relevant clinical findings are presented, and the cause and effect relationship between these two rare entities is discussed.
Inoue
S
S
Department of Pediatrics/Human Development, Michigan State University College of Human Medicine, East Lansing.
Gordon
R
R
Berner
G
G
D002675:Child, Preschool; D003937:Diagnosis, Differential; D004890:Erythema / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008193:Lyme Disease / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008297:Male; D012867:Skin / Q000473:pathology