title: Clinicopathologic review of 142 cases of lacrimal gland lesions.
abstract: A review of 142 lacrimal gland biopsies performed during a 25-year period at a major eye hospital showed that 78% of lacrimal gland lesions were of nonepithelial origin and only 22% were primary epithelial neoplasms. The nonepithelial lesions included inflammation (64%) and lymphoid tumors (14%), whereas the epithelial lesions included dacryops (6%), pleomorphic adenoma (12%), and malignant epithelial tumors (4%). These results contradict the much quoted dictum that 50% of lacrimal gland lesions are primary epithelial tumors and 50% are nonepithelial lesions.
authors.affiliation: Oncology Service, Wills Eye Hospital, Philadelphia, PA.
authors.forename: C L
authors.initials: CL
authors.lastname: Shields
authors.forename: J A
authors.initials: JA
authors.lastname: Shields
authors.forename: R C
authors.initials: RC
authors.lastname: Eagle
authors.forename: J P
authors.initials: JP
authors.lastname: Rathmell
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000236:Adenoma / Q000473:pathology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D002277:Carcinoma / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D007766:Lacrimal Apparatus Diseases / Q000145:classification / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000473:pathology*; D012189:Retrospective Studies