[Detection of early pregnancy factor by the rosette inhibition test: use of cyclosporin A].
For the detection of the early pregnancy factor (EPF) as early pregnancy signal and as tumour marker only the rosette inhibition test is generally accepted. In the testing of 10 EPF-positive and 10 EPF-negative sera the immunosuppressive agent cyclosporine A was used for the first time. The differences between both groups were highly significant (alpha less than 0.001). Similar results were obtained by using the more expensive anti-human T lymphocyte globulin.
Straube
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W
Klinik für Gynäkologie und Geburtshilfe, Ernst-Moritz-Arndt-Universität Greifswald.
Loh
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M
D018835:Chaperonin 10; D003524:Cyclosporins; D005260:Female; D006801:Humans; D010455:Peptides / Q000032:analysis*; D011247:Pregnancy; D011257:Pregnancy Proteins; D011259:Pregnancy Tests, Immunologic; D012397:Rosette Formation; D013491:Suppressor Factors, Immunologic
D018835:Chaperonin 10; D003524:Cyclosporins; D010455:Peptides; D011257:Pregnancy Proteins; D013491:Suppressor Factors, Immunologic; C025124:early pregnancy factor
Nachweis des Early Pregnancy Factor mittels Rosettenhemmtest: Anwendung von Ciclosporin A.