Evoked potentials in chronic n-hexane intoxication.
Somatosensory, brainstem auditory and pattern-reversal visual evoked potentials (SEP, BAEP and PVEP) were studied in 5 patients with n-hexane polyneuropathy to determine if the CNS was affected. In SEPs, the median central conduction (N13-to-N20) was normal but the tibial central conduction (N22-to-P40) was delayed. The central conduction time (I-to-V interval) of the BAEP was also prolonged. However, the P100 latency of the PVEP was normal. The present data indicate that the spinal cord and the brainstem are primarily affected in chronic n-hexane intoxication.
Huang
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CC
Department of Neurology, Chang Gung Medical College, Taipei, Taiwan, Republic of China.
Chu
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NS
D000293:Adolescent; D000328:Adult; D002493:Central Nervous System Diseases / Q000139:chemically induced / Q000503:physiopathology*; D004781:Environmental Exposure; D005072:Evoked Potentials, Auditory; D005073:Evoked Potentials, Somatosensory; D005074:Evoked Potentials, Visual; D006586:Hexanes / Q000506:poisoning*; D006801:Humans; D008297:Male; D009431:Neural Conduction
D006586:Hexanes; C026385:n-hexane