[Proteus syndrome. A contribution to the further differential diagnosis of congenital local gigantism].
Four sporadically occurring characteristic cases of the Proteus syndrome are described. All patients show the main features of the disease, consisting of hemihypertrophy, partial gigantism of hands and/or feet with soft-tissue hypertrophy, plane naevi, subcutaneous tumours, and cranial anomalies. There is a remarkable polymorphism of the symptoms. Anamnestic, clinical and paraclinical findings are shown in tables. Based on a survey of the literature, the main aspects of genetics and of differential diagnosis are discussed.
Trappe
B O
BO
Klinik für Kinderheilkunde der Medizinischen Akademie Magdeburg, DDR.
Rupprecht
E
E
Bosselmann
E
E
Schaeper
M
M
Mohnike
K
K
Gedschold
J
J
D000015:Abnormalities, Multiple / Q000235:genetics; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D005532:Foot Deformities, Congenital / Q000235:genetics*; D005877:Gigantism / Q000235:genetics*; D006228:Hand Deformities, Congenital / Q000235:genetics*; D006801:Humans; D008297:Male; D013577:Syndrome
Das Proteus-Syndrom. Ein Beitrag zur weiteren Differentialdiagnose des angeborenen örtlichen Riesenwuchses.