[Immunologic examination of Juzentaiho-to (TJ-48) in postoperative gastric cancer].
We earlier reported the clinical effects of TJ-48 on side-effects of anti-tumor agents. In this report an immunological examination was conducted on administration of TJ-48 for postoperative gastric cancer.


METHODS
Blast formation of mouse lymphocyte to which patient serum was added. TNF activity, LAK activity and 2-5AS activity before and after administration of TJ-48 were measured in 19 cases of gastric cancer.


RESULTS
Blast formation of mouse lymphocytes after administration showed a tendency to increase more than before. TNF activities tended to decrease more after administration than before. 2-5AS activities indicated a tendency to decrease more after administration than before. Little difference was manifest between LAK activities before and after administration.


CONCLUSIONS
The action of non-specific immunosuppressive factor was suggested to be lowered after administration of TJ-48 for postoperative gastric cancer.
Kurokawa
T
T
1st Dept. of Surgery, National Defense Medical College.
Tamakuma
S
S
Imai
J
J
Yamamoto
T
T
Taguchi
J
J
D015088:2',5'-Oligoadenylate Synthetase / Q000097:blood; D000328:Adult; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D005743:Gastrectomy; D006801:Humans; D007694:Killer Cells, Natural / Q000187:drug effects / Q000276:immunology; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D051379:Mice; D008875:Middle Aged; D011184:Postoperative Period; D013274:Stomach Neoplasms / Q000097:blood / Q000276:immunology* / Q000601:surgery; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
D004365:Drugs, Chinese Herbal; D014409:Tumor Necrosis Factor-alpha; D015088:2',5'-Oligoadenylate Synthetase