[The role of osmotic factors in the effect of mineral water Naftusia on smooth muscles of the portal vein].
The effect of the Krebs solution tonicity on the electrical and mechanical activity of smooth muscles has been studied while adding 1-5% volume of mineral water Naftusya, its artificial salt analog, and distilled water into the above solution. It is shown that effects observed are induced by the medium tonicity changes rather than by biologically active components of the mineral water. The smooth muscle cells of the rat portal vein are sensitive osmometers which affect hypotonic Krebs solution by 1%.
Zagorodniuk
V P
VP
Baev
E Ia
EIa
Iaremenko
M S
MS
D000818:Animals; D003470:Culture Media; D066298:In Vitro Techniques; D007552:Isotonic Solutions; D008900:Mineral Waters; D009119:Muscle Contraction; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000502:physiology*; D009994:Osmolar Concentration; D011169:Portal Vein / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D014455:Ukraine
D003470:Culture Media; D007552:Isotonic Solutions; C051865:Krebs-Ringer solution; D008900:Mineral Waters
Rol' osmoticheskogo faktora v deĭstvii mineral'noĭ vody naftisi na gladkie myshtsy vorotnoĭ veny.