[Correlation values of total cholesterol and cholesterol in lipoprotein fractions in maternal serum and umbilical cord blood in high risk pregnancy].
In 20 healthy and 40 high-risk pregnancy women (diabets mellitus and EPH gestosis) total cholesterol and cholesterol in lipoprotein fractions were estimated. This was done in mothers' sera and cord blood by using the "Lipoprotein Proffiling System Beckman". Total cholesterol was significantly increased in the sera of diabetic mothers (7.775 mmol/L, SD 1.512 in healthy and 10.475 mmol/L, SD 2.102 in diabetic mothers); it was slightly increased in the cord. In all groups with high-risk pregnancy HDL cholesterol was significantly decreased (1.539 mmol/L, SD 0.449 in healthy and 1.240 mmol/L, SD 0.179 in diabetic mothers; EPH gestoses 1.241 mol/L, SD 0.222); it was slightly decreased in the umbilical cord in the cases with EPH gestosis. LDL cholesterol values were significantly increased in diabetic mothers' sera (3.782 mmol/L, SD 1.174 in healthy and 4.616 mmol/L, SD 1.275 in diabetic pregnant women); in those with EPH gestoses they were on the borderline of significance. In mothers' sera of all high-risk groups VLDL cholesterol values were significantly increased (2.470 mmol/L, SD 1022 in healthy and 4.837 mmol/L, SD 1.484 in diabetic pregnant women; EPH gestoses 3.641 mmol/L, SD 0.974), while in the cord they were increased only in diabetic women and EPH gestoses (0.232 mmol/L, SD 0.186 in healthy and 0.650 mmol/L, SD 0.405 in diabetic women; EPH gestoses 0.497 mmol/L, SD 0.104).
Rosić
B
B
D000328:Adult; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D015243:Cholesterol, VLDL / Q000097:blood; D005260:Female; D005312:Fetal Blood / Q000032:analysis*; D006801:Humans; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000097:blood*
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D015243:Cholesterol, VLDL; D002784:Cholesterol
Korelacija vrednosti ukupnog holesterola i holesterola u lipoproteinskim frakcijama iz seruma majki i pupcanika fetusa u visoko rizicnim trudnoćama.