An automatic syringe for coronary occlusion in long-term collateralization studies.
A portable apparatus for performing repeated, brief coronary artery occlusions automatically in long-term chronic studies involving dogs and larger animals is described. The battery-operated, back-pack-carried device uses a motorized syringe driven by a digital-programmable timing circuit to inflate a coronary artery occluder for durations of 10 s to 3 min at intervals from 14 s to 16 h. A single battery charge produces 450 occlusions. The generated pressure is adjustable to 1,000 mmHg maximum. A separate fail-safe circuit monitors system operation to open a pressure-relief valve if occlusions exceed a preset duration.
Caldwell
W M
WM
Dalton Research Center, University of Missouri, Columbia 65211.
McKown
D P
DP
Bleck
J A
JA
Hartley
J W
JW
Erdal
T
T
Barrett
E E
EE
Franklin
D
D
D000818:Animals; D003326:Coronary Circulation; D003327:Coronary Disease / Q000503:physiopathology*; D004195:Disease Models, Animal; D004285:Dogs; D004594:Electrophysiology / Q000295:instrumentation / Q000379:methods; D013594:Syringes