title: Effectiveness of intramammary antibiotic therapy based on somatic cell count.
abstract: The Virginia Tech dairy herd was used in a 10-mo study to determine the effect of intramammary antibiotic therapy of quarters with elevated SCC on milk production, subsequent DHIA SCC, and infection status. Cows were assigned randomly to experimental or control groups. Animals in both the control and experimental groups with SCC scores greater than or equal to 5 for the first time during that lactation were quarter sampled, milk was cultured to detect presence of mastitis pathogens, and SCC was determined. All experimental cows with quarter SCC greater than or equal to 5 were treated with an intramammary cephapirin product only in those elevated quarters (DHIA SCC greater than or equal to 5), regardless of clinical symptoms. Control cows received antibiotic therapy when symptoms were clinical, regardless of SCC. Treatment group had no significant effect on milk production, SCC, or infection status of the cow. Treatment of cows in the experimental group cured 70% of infected quarters, whereas only 50% of infections in the control group were eliminated.
authors.affiliation: Department of Dairy Science, Virginia Polytechnic Institute and State University, Blacksburg 24061.
authors.forename: E H
authors.initials: EH
authors.lastname: Seymour
authors.forename: G M
authors.initials: GM
authors.lastname: Jones
authors.forename: M L
authors.initials: ML
authors.lastname: McGilliard
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy; D002452:Cell Count; D002511:Cephalosporins / Q000627:therapeutic use*; D002514:Cephapirin / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D007774:Lactation; D008321:Mammary Glands, Animal / Q000382:microbiology; D008414:Mastitis, Bovine / Q000188:drug therapy* / Q000382:microbiology; D008892:Milk / Q000166:cytology*; D011247:Pregnancy; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000662:veterinary; D013290:Streptococcal Infections / Q000188:drug therapy / Q000662:veterinary
chemical_list: D002511:Cephalosporins; D002514:Cephapirin