title: Change in the summating potential and action potential during the fluctuation of hearing in Ménière's disease.
abstract: Summating potential (SP) and action potential (AP) were monitored by extratympanic electrocochleography (ECoG) during the fluctuation of hearing in 8 patients with Ménière's disease. The relationship of SP and AP parameters to pure-tone hearing threshold level was examined. The correlational analysis revealed the following: AP amplitude decreases with increase in the hearing threshold level at higher frequencies (2-8 kHz), whereas it alters independently of the change in the hearing threshold level at lower frequencies (0.25-1 kHz). -SP amplitude is unchanged irrespective of changes in the hearing threshold level at any frequency. The ratio of -SP to AP amplitude increases with increase in the hearing threshold level at higher frequencies (2-8 kHz), whereas it alters independently of the change in the hearing threshold level at lower frequencies (0.25-1 kHz).
authors.affiliation: Department of Otolaryngology, Osaka University Medical School, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Asai
authors.forename: N
authors.initials: N
authors.lastname: Mori
mesh_terms: D000200:Action Potentials; D000328:Adult; D001300:Audiometry, Evoked Response; D001309:Auditory Threshold / Q000502:physiology; D003051:Cochlea / Q000503:physiopathology*; D005072:Evoked Potentials, Auditory; D005260:Female; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000503:physiopathology*; D008875:Middle Aged