Hyperbaric oxygen: primary treatment of radiation-induced hemorrhagic cystitis.
Of 8 patients with symptoms of advanced cystitis due to pelvic radiation treated with hyperbaric oxygen 7 are persistently improved during followup. All 6 patients treated for gross hematuria requiring hospitalization have been free of symptoms for an average of 24 months (range 6 to 43 months). One patient treated for stress incontinence currently is dry despite little change in bladder capacity, implying salutary effect from hyperbaric oxygen on the sphincter mechanism. One patient with radiation-induced prostatitis failed to respond. This experience suggests that hyperbaric oxygen should be considered the primary treatment for patients with symptomatic radiation-induced hemorrhagic cystitis.
Weiss
J P
JP
Department of Surgery, Temple University School of Medicine, Philadelphia, Pennsylvania.
Neville
E C
EC
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003556:Cystitis / Q000209:etiology / Q000628:therapy*; D005260:Female; D006417:Hematuria / Q000628:therapy; D006470:Hemorrhage / Q000209:etiology / Q000628:therapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000532:radiotherapy; D011472:Prostatitis / Q000628:therapy; D011832:Radiation Injuries / Q000628:therapy*; D013684:Telangiectasis / Q000628:therapy; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy