Interdependence of urinary factors in calcareous bladder stone patients.
Twenty-four-hour urinary excretion of calcium, oxalic acid, inorganic phosphorus, magnesium and citric acid was examined in fifty-nine stone formers with bladder stones. Hypercalciuria and hyperoxaluria were present in 18.6% and 44.1%, respectively, while 11.9% of patients had both abnormalities. Hypomagnesuria and hypocitraturia were present in 67.8% and 69.5%, respectively, while 45.7% had both of these abnormalities. Normal urine chemistry in respect of parameters studied was observed only in 1.7% of cases. In 15.2% one risk factor was present, while 83.1% had two or more risk factors. "Path" analysis of the urinary parameters directly related to calcium lithiasis showed that magnesium and oxalic acid have substantial influence on calcium excretion, whereas citric acid had none. The influence of phosphorus did not provide any consistent trend.
Singh
P P
PP
Department of Biochemistry and Surgery, R.N.T. Medical College Udaipur, India.
Pendse
A K
AK
Rathore
V
V
Kiran
R
R
Dashora
P K
PK
D002118:Calcium / Q000652:urine*; D002951:Citrates / Q000652:urine; D019343:Citric Acid; D006801:Humans; D008274:Magnesium / Q000652:urine; D010070:Oxalates / Q000652:urine; D019815:Oxalic Acid; D010758:Phosphorus / Q000652:urine; D012307:Risk Factors; D001744:Urinary Bladder Calculi / Q000652:urine*
D002951:Citrates; D010070:Oxalates; D010758:Phosphorus; D019343:Citric Acid; D019815:Oxalic Acid; D008274:Magnesium; D002118:Calcium