title: Orbital exenteration at the Mayo Clinic. 1967-1986.
abstract: Orbital exenteration was performed in 102 patients at the Mayo Clinic during the 20-year period from 1967 through 1986. The surgical procedure was performed for mucormycosis in one patient and for pain and deformity after a severe facial burn in another; in the remaining 100 patients, exenteration was used to treat a neoplastic disorder. Although 19 different neoplasms were encountered, squamous cell carcinoma, basal cell carcinoma, and melanoma constituted 70% of the total. In 82 patients with no known residual tumor or metastases at operation, the 1-year survival rate was 88.6%, the 5-year rate was 56.8%, and the 5-year rate free of recurrence or metastases was 48.3%. In 18 patients with known residual tumor or metastases at exenteration, 55.0% were alive 1 year postoperatively, and the 5-year survival rate was 25.8%. Unusual findings in this series included two patients with metastatic basal cell carcinoma and one patient with a metastatic thyroid Hürthle cell carcinoma.
authors.affiliation: Department of Ophthalmology, Mayo Clinic, Rochester, MN 55905.
authors.forename: G B
authors.initials: GB
authors.lastname: Bartley
authors.forename: J A
authors.initials: JA
authors.lastname: Garrity
authors.forename: R R
authors.initials: RR
authors.lastname: Waller
authors.forename: J W
authors.initials: JW
authors.lastname: Henderson
authors.forename: D M
authors.initials: DM
authors.lastname: Ilstrup
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D015353:Eye Enucleation; D005131:Eye Injuries / Q000209:etiology / Q000601:surgery; D005260:Female; D006777:Hospitals, Proprietary; D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis*; D008875:Middle Aged; D009091:Mucormycosis / Q000601:surgery; D009918:Orbital Neoplasms / Q000601:surgery; D011379:Prognosis; D013997:Time Factors