The in-vitro effect of an amine fluoride gel on subgingival plaque bacteria.
Subgingival plaque samples obtained from 25 patients with chronic inflammatory periodontal disease were exposed in vitro to a commercial dental gel formulation containing two amine fluorides. High dilutions (1 in 32) of the gel inhibited the growth of all cultivable bacteria in all of the samples. Lower concentrations of gel were still effective, with a 1 in 128 dilution of the gel, corresponding to an amine fluoride concentration of 260 mg/l, inhibiting 97.5% of the bacteria in the samples.
Bullock
S
S
Department of Clinical Pathology and Immunology, Institute of Dental Surgery, London, UK.
Newman
H N
HN
Wilson
M
M
D000588:Amines / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D002453:Cell Cycle / Q000187:drug effects; D003773:Dental Plaque / Q000382:microbiology*; D003959:Diamines; D005459:Fluorides; D005782:Gels; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests; D010518:Periodontitis / Q000382:microbiology*
D000588:Amines; D003959:Diamines; D005782:Gels; C495399:Olaflur; D005459:Fluorides