Morphometric assessment of ovarian stromal proliferation--a clinicopathological study.
Ovarian stromal hyperplasia is commonly observed in peri- and post-menopausal ovaries. Assessment has, hitherto, been largely subjective or dependent on arbitrary criteria, which has made comparison of studies difficult. In this study, the stroma of a large number of ovaries was assessed morphometrically. Data were related to clinicopathological and cytomorphological information. A significant association was noted between the degree of stromal proliferation and post-menopausal endometrial adenocarcinoma (P = 0.004). There were no significant correlations between the degree of stromal proliferation and average cytomorphological dimensions.
Snowden
J A
JA
Department of Pathology, University of Leeds, UK.
Harkin
P J
PJ
Thornton
J G
JG
Wells
M
M
D000230:Adenocarcinoma / Q000150:complications / Q000473:pathology*; D000328:Adult; D000368:Aged; D000375:Aging / Q000473:pathology*; D005260:Female; D006801:Humans; D006965:Hyperplasia; D008875:Middle Aged; D010049:Ovarian Diseases / Q000150:complications / Q000473:pathology*; D014594:Uterine Neoplasms / Q000150:complications / Q000473:pathology*