The stimulatory effect of bilirubin on phagocytic activity.
The effect of an i.p. application of bilirubin on phagocytic activity and the arrangement of the microtubule system of murine peritoneal macrophages were examined. A significant increase of phagocytic activity was observed 3 h after bilirubin treatment, and normal value were reached after 3 d. The increase of the extent of the microtubule system was comparable with that of enhanced phagocytosis but normal values were observed after 1 d.
Bilej
M
M
Institute of Microbiology, Czechoslovak Academy of Sciences, Prague.
Vĕtvicka
V
V
Síma
P
P
D000818:Animals; D001663:Bilirubin / Q000494:pharmacology*; D008264:Macrophages / Q000187:drug effects / Q000502:physiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008870:Microtubules / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*; D010529:Peritoneal Cavity / Q000166:cytology*; D010587:Phagocytosis / Q000187:drug effects*
D001663:Bilirubin