title: Umbilical artery blood flow velocity waveforms and associations with fetal abnormality.
abstract: Blood flow velocity waveforms from the umbilical artery of 126 normal fetuses with no evident complications at 20-42 weeks of gestation and 15 fetuses with various abnormalities at 25-42 weeks were recorded using pulsed Doppler ultrasound. The resistance index (RI) was assessed on each blood flow velocity waveform. In 9 fetuses with a slight abnormality, the values of RI were within the mean +/- 2 SD of normal fetuses, and the outcome was good. In 3 of 6 fetuses with a serious abnormality, the values of the RI were high, and 2 of these fetuses died in utero within a few days after the recording. Another fetus with a high RI and 3 with a normal RI died neonatally. Therefore, Doppler ultrasound assessments of the umbilical artery blood flow velocity waveform in utero aid in predicting the outcome for fetuses with major abnormalities.
authors.affiliation: Department of Obstetrics and Gynecology, Shimane Medical University, Izumo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Hata
authors.forename: T
authors.initials: T
authors.lastname: Hata
authors.forename: D
authors.initials: D
authors.lastname: Senoh
authors.forename: S
authors.initials: S
authors.lastname: Aoki
authors.forename: O
authors.initials: O
authors.lastname: Takamiya
authors.forename: M
authors.initials: M
authors.lastname: Kitao
mesh_terms: D001783:Blood Flow Velocity; D000013:Congenital Abnormalities / Q000503:physiopathology*; D005260:Female; D005333:Fetus / Q000502:physiology*; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome; D014465:Ultrasonics; D014469:Umbilical Arteries / Q000502:physiology*; D014655:Vascular Resistance