title: [The use of a tripeptide chromogenic substrate for simultaneous determination of 4 indices of kallikrein-kinin system].
abstract: Evaluation of the kallikrein-kinine system activity in blood plasma is of importance due to participation of the components of this system in regulation of blood plasma proteolysis. Using D-Pro-Phe-Arg-pNA as a substrate, a procedure for simultaneous estimation of four patterns of the kallikrein-kinine system activity was developed: I. maintenance of contact phase, 2. content of prekallikrein (1.49 un/ml in normal state), 3. activity of kallikrein (0.104 un/ml), 4. antikallikrein potential (0.700 IU/ml).
authors.forename: V L
authors.initials: VL
authors.lastname: Dotsenko
authors.forename: G A
authors.initials: GA
authors.lastname: Iarovaia
authors.forename: E A
authors.initials: EA
authors.lastname: Neshkova
mesh_terms: D000581:Amidohydrolases / Q000097:blood; D002863:Chromogenic Compounds; D006801:Humans; D007610:Kallikreins / Q000037:antagonists & inhibitors / Q000097:blood*; D007700:Kinetics; D007705:Kinins / Q000097:blood*; D009842:Oligopeptides; D011288:Prekallikrein / Q000302:isolation & purification; D011480:Protease Inhibitors
chemical_list: D002863:Chromogenic Compounds; D007705:Kinins; D009842:Oligopeptides; D011480:Protease Inhibitors; C026148:prolyl-phenylalanyl-arginine-4-nitroanilide; D011288:Prekallikrein; D007610:Kallikreins; D000581:Amidohydrolases; C019665:amidase
vernacular_title: Ispol'zovanie tripeptidnogo khromogennogo substrata dlia odnovremennoĭ otsenki chetyrekh pokazateleĭ aktivnosti kallikrein-kininovoĭ sistemy.