title: A composite fixation principle for modular segmental defect replacement (SDR) prostheses.
abstract: A composite fixation concept for porous-coated modular segmental bone and joint replacement prostheses was developed. Bone cement will provide immediate intramedullary stem stability, whereas autogenous bone grafts are applied over the porous-coated segmental shoulder region to achieve extracortical bone bridging and ingrowth for long-term biologic fixation. Bench tests, theoretical analyses, and animal experiments were performed to validate such a concept. Preliminary clinical trials have demonstrated extraordinary results as well as several limiting factors. Additional effort is required to perfect this innovative concept for prosthetic implant fixation.
authors.affiliation: Department of Orthopedics, Mayo Clinic, Mayo Foundation, Rochester, Minnesota.
authors.forename: E Y
authors.initials: EY
authors.lastname: Chao
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D001846:Bone Development; D001842:Bone and Bones / Q000601:surgery*; D004285:Dogs; D005121:Extremities / Q000601:surgery*; D006801:Humans; D007103:Immobilization; D007595:Joint Prosthesis; D009369:Neoplasms / Q000601:surgery; D019736:Prostheses and Implants; D011474:Prosthesis Design