Adverse effect of intraoperative phenylephrine 10%: case report.
The case is reported of a patient who suffered severe acute hypertension, cardiac arrhythmia, and myocardial infarction probably as a direct effect of phenylephrine overdose. Instillation of the drops during surgery probably enhanced the systemic absorption of a significant amount of the drug. Therefore it should be used during surgery with caution, especially in elderly patients and those with cardiovascular disease.
Lai
Y K
YK
Department of Ophthalmology, Faculty of Medicine, University of Malaya, Malaysia.
D001145:Arrhythmias, Cardiac / Q000139:chemically induced*; D006801:Humans; D006973:Hypertension / Q000139:chemically induced*; D007431:Intraoperative Complications; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000139:chemically induced*; D010656:Phenylephrine / Q000008:administration & dosage / Q000506:poisoning*; D012163:Retinal Detachment / Q000601:surgery*
D010656:Phenylephrine