Aminophylline dosage in acute severe asthma.
In 27 cases of acute severe asthma, a loading dose of 5 mg/kg of aminophylline (omitted if already receiving oral theophylline) followed by a continuous infusion of 1 mg/kg per hour gave satisfactory theophylline levels at 4 h and 24 h. Theophylline clearance rates varied widely, vomiting was common, but unrelated to blood theophylline levels.
Gleeson
J G
JG
Department of Child Health, Kings's College Hospital Denmark Hill, London, United Kingdom.
Price
J F
JF
D000628:Aminophylline / Q000008:administration & dosage* / Q000493:pharmacokinetics / Q000627:therapeutic use; D001249:Asthma / Q000097:blood / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D013806:Theophylline / Q000097:blood
D000628:Aminophylline; D013806:Theophylline