[Effect of holotoxin A1 on microviscosity of model and biological membranes].
Behavior of hydrophobic probes of 5-doxylstearol acid and pyrene in phosphatidylcholine liposomes modified by sterols isolated from Far East holothurian tissues was studied. The introduction of delta 7-sterol xylosides and delta 5-sterol sulfates into liposomes was shown to result in an increase of the membranes microviscosity. When the liposome suspension was added with holotoxin A1 a supplementary increase of microviscosity was observed, which was obviously a consequence of glycosides +non built into the membranes.
Aminin
D L
DL
Osipov
A N
AN
Korepanova
E A
EA
Anisimov
M M
MM
D003497:Cyclic N-Oxides; D006027:Glycosides / Q000494:pharmacology*; D006697:Holothurin; D008081:Liposomes; D008566:Membranes; D010713:Phosphatidylcholines; D011721:Pyrenes; D012503:Saponins; D013113:Spin Labels; D014315:Triterpenes / Q000494:pharmacology*; D014783:Viscosity
D003497:Cyclic N-Oxides; D006027:Glycosides; D008081:Liposomes; D010713:Phosphatidylcholines; D011721:Pyrenes; D012503:Saponins; D013113:Spin Labels; D014315:Triterpenes; D006697:Holothurin; C005072:5-doxylstearic acid; C001883:stichoposide
Vliianie golotoksina A1 na mikroviazkost' model'nykh i biologicheskikh membran.