Impaired urine concentrating ability in Itai-itai (ouch-ouch) disease.
A case of Itai-itai (ouch-ouch) disease with reduced urinary kallikrein excretion and slightly enhanced renin-angiotensin-aldosterone system is described. Although it is well known that cadmium toxicity frequently affects the renal tubular lesions, this report is the first to demonstrate the impaired urine concentrating ability in this disease.
Nakada
T
T
Department of Urology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan.
Furuta
H
H
Koike
H
H
Katayama
T
T
Teranishi
H
H
D000368:Aged; D002105:Cadmium Poisoning / Q000188:drug therapy / Q000503:physiopathology* / Q000652:urine; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging / Q000503:physiopathology*; D007671:Kidney Concentrating Ability; D011877:Radionuclide Imaging; D012084:Renin-Angiotensin System; D014057:Tomography, X-Ray Computed; D014563:Urodynamics
D003894:Deamino Arginine Vasopressin