title: A new device for transcatheter closure of the patent ductus arteriosus. A feasibility study in dogs.
abstract: A new device for transcatheter closure of the patent ductus arteriosus was developed and initially evaluated in the vasculature of adult mongrel dogs. The device consists of a nylon sack that can be made in various sizes and shapes. A small flexible crossbar attached to the distal end maintains the position of the sack while it is filled with a segment of modified guide wire. The device is delivered coaxially through a 10-Fr Teflon catheter and is easily repositioned or retrieved before release. The expansile force of the sack against the vessel wall can be varied, and its stability is easily checked prior to detachment. The device produced immediate and permanent vascular occlusion without inflammation or erosion. Over time, the entire unit became incorporated into the vessel wall by neointimal encasement. Nylon sacks offer a simple, unique method of closing virtually any ductus arteriosus without general anesthesia and major surgery.
authors.affiliation: University of Texas, M.D. Anderson Cancer Center, Department of Diagnostic Radiology, Houston 77030.
authors.forename: C
authors.initials: C
authors.lastname: Magal
authors.forename: K C
authors.initials: KC
authors.lastname: Wright
authors.forename: G
authors.initials: G
authors.lastname: Duprat
authors.forename: S
authors.initials: S
authors.lastname: Wallace
authors.forename: C
authors.initials: C
authors.lastname: Gianturco
mesh_terms: D000818:Animals; D006328:Cardiac Catheterization; D004285:Dogs; D004374:Ductus Arteriosus, Patent / Q000628:therapy*; D004621:Embolization, Therapeutic / Q000295:instrumentation*; D004864:Equipment and Supplies; D009757:Nylons
chemical_list: D009757:Nylons