Role of thromboxane A2, leukotriene C4 and histamine in the antigen-induced vasoconstriction in perfused, sensitized guinea-pig kidney.
The existence of a role for TXA2, histamine, and possibly LTC4 in the antigen-induced renal vasoconstriction in isolated, perfused kidney of sensitized guinea-pigs is demonstrated.
Abdullah
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NA
Department of Pharmacology, University College, London, UK.
Assem
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ES
D000818:Animals; D000941:Antigens; D006168:Guinea Pigs; D006632:Histamine / Q000276:immunology; D007114:Immunization; D066298:In Vitro Techniques; D007668:Kidney / Q000098:blood supply / Q000187:drug effects / Q000276:immunology*; D010047:Ovalbumin / Q000276:immunology; D010477:Perfusion; D011738:Pyrilamine / Q000494:pharmacology; D013189:SRS-A / Q000037:antagonists & inhibitors / Q000276:immunology; D013928:Thromboxane A2 / Q000037:antagonists & inhibitors / Q000276:immunology; D014661:Vasoconstriction / Q000187:drug effects
D000941:Antigens; D013189:SRS-A; D013928:Thromboxane A2; D006632:Histamine; D010047:Ovalbumin; D011738:Pyrilamine