[Arteriosclerosis and blood lipids].
In our examinations of the new-born and their parents, of the patients with coronary heart disease and their relations, of the healthy test persons of different age and of the families of the long-lived persons we have found that in the atherogenesis genetic factors and blood lipids play a great part. In future it is perhaps possible already early to recognize in children a genetically conditioned hyperlipoproteinaemia, all the more since in the patients with hereditary load was to be observed a clear increase of the indices of lipid metabolism in comparison to the healthy test persons. Furthermore, a connection between a hyperlipoproteinaemia and the AB0 blood groups was stated. A combination of the hyperlipoproteinaemia of type IIb with the blood group A in new-born and in patients after myocardial infarction belongs to the most important risk factors for the atherogenesis. On account of these findings it is possible to establish a hyperlipoproteinaemia in childhood in children with hereditary load, which gives the possibility by means of normalization of the lipids to perform an early prophylaxis of the arteriosclerosis. The examination of the long-lived persons showed that the arteriosclerosis is not certainly an accompanying appearance of old age, for the autopsies of persons 100 years of age and more did not show any arteriosclerotic changes of the vessels.
Kipschidse
N N
NN
Forschungsinstitut für experimentelle und klinische Therapie, Georgischen Sowjetrepublik Tbilissi.
Schawgulidse
N A
NA
D000017:ABO Blood-Group System / Q000235:genetics; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D003324:Coronary Artery Disease / Q000097:blood / Q000235:genetics*; D005260:Female; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000097:blood / Q000235:genetics*; D007231:Infant, Newborn; D008055:Lipids / Q000097:blood*; D008297:Male; D009203:Myocardial Infarction / Q000235:genetics; D012307:Risk Factors
D000017:ABO Blood-Group System; D008055:Lipids
Die Arteriosklerose und die Blutlipide.