title: Bilateral vocal cord paralysis with respiratory failure. A presenting manifestation of bronchogenic carcinoma.
abstract: A patient with lung cancer presented with upper airway obstruction and hypercapnic respiratory failure resulting from bilateral vocal cord paralysis. Computed tomography demonstrated tumor extension into the superior mediastinum, with probable disruption of both recurrent laryngeal nerves. Unlike the more common unilateral cord paralysis, bilateral cord dysfunction is often associated with preservation of voice and varying degrees of stridor that may lead to potentially life-threatening delays in diagnosis and treatment. Proper management requires urgent translaryngeal intubation if airway obstruction is high grade, with subsequent consideration of laryngeal surgical procedures for long-term care.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Medical University of South Carolina, Charleston 29425.
authors.forename: M H
authors.initials: MH
authors.lastname: Baumann
authors.forename: J E
authors.initials: JE
authors.lastname: Heffner
mesh_terms: D000402:Airway Obstruction / Q000209:etiology*; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000473:pathology; D003390:Cranial Nerve Neoplasms / Q000150:complications* / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications / Q000473:pathology; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012009:Recurrent Laryngeal Nerve / Q000473:pathology; D012131:Respiratory Insufficiency / Q000209:etiology*; D014826:Vocal Cord Paralysis / Q000209:etiology*