Simultaneous appearance of agranulocytosis and cholestatic jaundice following chlorpromazine treatment.
A young schizophrenic patient developed cholestatic jaundice and agranulocytosis during chlorpromazine (CPZ) therapy. Mechanisms responsible for these complications are discussed.
Sidi
Y
Y
Department of Medicine D, Beilinson Medical Center, Tel Aviv University Medical School, Petah Tikva, Israel.
Douer
D
D
Pinkhas
J
J
D000208:Acute Disease; D000328:Adult; D000380:Agranulocytosis / Q000139:chemically induced* / Q000473:pathology; D002746:Chlorpromazine / Q000009:adverse effects*; D002779:Cholestasis / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D006801:Humans; D012559:Schizophrenia / Q000150:complications / Q000188:drug therapy
D002746:Chlorpromazine