Repetitive burst-firing neurons in the deep layers of mouse somatosensory cortex.
Intracellular recordings were made from neurons of the mouse somatosensory cortex isolated in vitro. Two physiologically distinct classes of pyramidal cells were observed: regular-spiking cells were the majority, and generated accommodating trains of single spikes; bursting cells generated clusters of 2-5 action potentials, and clusters were separated by prolonged afterhyperpolarizations. The bursting cells of the mouse neocortex were unusual in producing repetitive bursting during sustained current pulses, and in being localized to a laminar zone straddling layers V and VI.
Agmon
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Department of Neurology, Stanford University School of Medicine, CA 94305.
Connors
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BW
D000818:Animals; D005073:Evoked Potentials, Somatosensory; D066298:In Vitro Techniques; D051379:Mice; D008810:Mice, Inbred C57BL; D009474:Neurons / Q000145:classification / Q000502:physiology; D013003:Somatosensory Cortex / Q000502:physiology*