title: Alteration of pulmonary oxygenation by pulmonary artery occluded pressure measurements in mechanically ventilated patients.
abstract: A significant decrease in PaO2 occurs in some patients during PAOP measurements. To examine the incidence and the types of patients whose PaO2 decreases during PAOP measurements, we studied the changes of PaO2 in 101 anesthetized, mechanically ventilated adult patients. During a 2-min inflation of a PAC balloon, seven patients (6.9 percent) developed marked decrease in PaO2/FIo2 (more than 100 mm Hg). Neither age nor size of patients, decrease in end-tidal CO2, nor baseline value of PAP correlated with the decreases in PaO2. A decrease in PaO2/FIo2 (more than 50 mm Hg) was observed more frequently in female patients and in patients with cardiac disease, especially those whose PAP values were above normal. Although a significant decrease in PaO2 during PAOP measurements does not appear to occur often, our results suggest that the changes in PaO2 should be evaluated in patients with severely compromised pulmonary oxygenation.
authors.affiliation: Department of Anesthesiology, University of Tsukuba, Ibaraki, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Ishizawa
authors.forename: S
authors.initials: S
authors.lastname: Dohi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002407:Catheterization, Swan-Ganz / Q000009:adverse effects*; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000502:physiology; D011659:Pulmonary Gas Exchange; D011669:Pulmonary Wedge Pressure; D012121:Respiration, Artificial