title: Subtle gastric abnormalities in a canine model: detection with low-dose imaging with storage phosphors and its equivalence to conventional radiography.
abstract: The authors compared low-dose (32% of standard exposure) storage phosphor digital imaging (system resolution: 0.2-mm pixels, 10 bits) with isovoltage 75-kVp conventional radiography (standard exposure) in the detection of subtle simulated gastric abnormalities by using air contrast barium studies. Subtle simulated abnormalities (3-7-mm polyps, 4-15-mm ulcer craters, 4-11-mm-diameter edema, and 11-12-mm linear ulcers) were produced in resected canine stomachs. Receiver operating characteristic analysis of 1,800 observations by six readers indicated that the digital images with and without high-frequency edge enhancement were equivalent to conventional radiographs (mean receiver operating characteristic areas [+/- standard deviation]: 0.76 +/- 0.06, 0.78 +/- 0.04, and 0.77 +/- 0.04, respectively). The accuracy of the diagnosis was equivalent for all three modalities. The following mean accuracies of negative and positive responses, respectively, for unenhanced digital, edge-enhanced digital, and conventional images were determined: 0.71 +/- 0.05 and 0.41 +/- 0.07, 0.71 +/- 0.04 and 0.51 +/- 0.09, and 0.68 +/- 0.04 and 0.43 +/- 0.05. It was concluded that low-dose storage phosphor air-contrast barium studies were equivalent to conventional radiography in the detection of subtle gastric abnormalities.
authors.affiliation: Department of Radiology, Massachusetts General Hospital, Boston.
authors.forename: J H
authors.initials: JH
authors.lastname: Shin
authors.forename: J
authors.initials: J
authors.lastname: Oestmann
authors.forename: D
authors.initials: D
authors.lastname: Hall
authors.forename: G
authors.initials: G
authors.lastname: Cardenosa
authors.forename: K A
authors.initials: KA
authors.lastname: McCarthy
authors.forename: H E
authors.initials: HE
authors.lastname: Mrose
authors.forename: E
authors.initials: E
authors.lastname: Pile-Spellman
authors.forename: J R
authors.initials: JR
authors.lastname: Rubens
authors.forename: R E
authors.initials: RE
authors.lastname: Greene
mesh_terms: D000818:Animals; D004285:Dogs; D066298:In Vitro Techniques; D012372:ROC Curve; D011856:Radiographic Image Enhancement; D013272:Stomach Diseases / Q000000981:diagnostic imaging*; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging; D013276:Stomach Ulcer / Q000000981:diagnostic imaging