[New data on the type of structural changes in DNA of simian adenovirus SA7 microinjected into mouse zygotes].
The structure of the transgene has been analysed in a new series of experiments on the transfer of adenovirus SA7 DNA into the mice zygotes by microinjection technique. The previous data on SA7 DNA elimination from the genomes of different organs (sceletal muscles, heart, tail) have been confirmed and detailed for the F0 and F1 generations of transgenic animals. The left end of adenoviral genome has been shown to be predominantly transfered after microinjections of SA7 DNA into the mice zygotes.
Kuznetsova
E D
ED
Andreeva
L E
LE
Serova
I A
IA
Trenkner
A
A
Tarantul
V Z
VZ
D000256:Adenoviridae / Q000235:genetics*; D000261:Adenoviruses, Simian / Q000235:genetics*; D000818:Animals; D004279:DNA, Viral / Q000235:genetics*; D051379:Mice; D008822:Mice, Transgenic; D008845:Microinjections; D009693:Nucleic Acid Hybridization; D014162:Transfection; D015053:Zygote
D004279:DNA, Viral
Novye dannye o kharaktere strukturnykh izmeneniĭ DNK adenovirusa obez'ian SA7, mikroin''etsirovannoĭ v zigoty mysheĭ.