[(Arylpiperazino-4-butyryl)-6 benzoxazolinones and reduction products: chemistry and pharmacodynamic study].
The synthesis of various 6-(4-arylpiperazino-butyryl)-3-methyl-benzoxazolinones and their reduction products, 6-(4-arylpiperazino-1-hydroxy-butyl)-3-methyl-benzoxazolinones and 6-(4-arylpiperazino-butyl)-3 methyl-benzoxzolinones, is described. These compounds were tested for psychotropic and analgesic activities.
Moussavi
Z
Z
Bonte
J P
JP
Lesieur
D
D
Leinot
M
M
Lamar
J C
JC
Tisne-Versailles
J
J
D000818:Animals; D001583:Benzoxazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D051379:Mice; D010084:Oxidation-Reduction; D010880:Piperidines / Q000138:chemical synthesis* / Q000494:pharmacology; D011619:Psychotropic Drugs / Q000138:chemical synthesis*; D051381:Rats
D001583:Benzoxazoles; D010880:Piperidines; D011619:Psychotropic Drugs
(Arylpipérazino-4 butyrl)-6 benzoxazolinones et preduits de réduction: étude chimique et pharmacodynamique.