Successful revascularization of an occluded renal artery after prolonged anuria.
Renal atherosclerosis and fibromuscular dysplasia are the most common causes of curable human renovascular hypertension and renal failure. Vascular reconstruction often preserves renal function, but renal failure is rarely reversed, especially after days of anuria. We report a case of a 23-year-old woman who as a child underwent a nephrectomy for congenital hydroureter and renal hypoplasia. She later experienced fibromuscular dysplasia of the remaining renal artery, which ultimately progressed to a complete occlusion and 31 days of total anuria. The patient was revascularized, and within 2 months renal function returned with a blood urea nitrogen and creatinine of 9.0 and 1.0 mg/dl, respectively. After a follow-up of 6 months the patient's blood pressure remained 120/80 to 130/80 mm Hg without administration of hypertension medication. In this report we emphasize that under selected circumstances a kidney can survive prolonged ischemia and that delayed revascularization may reestablish renal function.
Perona
P G
PG
Department of Surgery, Loyola University, Maywood, IL.
Baker
W H
WH
Fresco
R
R
Hano
J E
JE
D000328:Adult; D001002:Anuria / Q000209:etiology*; D001157:Arterial Occlusive Diseases / Q000601:surgery*; D004231:Diuresis; D005260:Female; D005352:Fibromuscular Dysplasia / Q000601:surgery*; D006801:Humans; D006978:Hypertension, Renovascular / Q000209:etiology* / Q000601:surgery; D007668:Kidney / Q000502:physiology; D007671:Kidney Concentrating Ability; D012078:Renal Artery Obstruction / Q000601:surgery*; D013997:Time Factors