title: [Stages and prospects of the development of morphologic studies in the field of environmental health].
abstract: Application of morphometric, histochemical and histoenzymatic examination techniques enabled one to detect early biologic effect of exposure to environmental chemical factors before the appearance of shifts in toxicologic indicators. A combination of characteristics involving damage and compensation reactions at the level of cells and cellular populations served as a hygienically significant criterion of adverse body effect of toxic substances. Biologic significance of morphologic criteria was confirmed by their correlation to the level of body resistance to specific load along with the degree of cellular stability, and by the comparison of morphologic shifts with the changes in physiologic and biochemical indicators. The prospects of development of morphologic studies in the field of environmental health are set forth.
authors.forename: T I
authors.initials: TI
authors.lastname: Bonashevskaia
mesh_terms: D056486:Chemical and Drug Induced Liver Injury / Q000473:pathology*; D004782:Environmental Health / Q000639:trends*; D004785:Environmental Pollutants / Q000009:adverse effects*; D006801:Humans; D009422:Nervous System Diseases / Q000139:chemically induced* / Q000473:pathology; D010336:Pathology / Q000639:trends*; D012140:Respiratory Tract Diseases / Q000139:chemically induced* / Q000473:pathology
chemical_list: D004785:Environmental Pollutants
vernacular_title: Etapy i perspektivy razvitiia morfologicheskikh issledovanii v oblasti gigieny okruzhaiushcheĭ sredy.