[Oxidative phosphorylation and lipid peroxidation of the liver mitochondria in rats after acute benzene poisoning].
The study revealed that after benzene-induced intoxication (CI50) there occurred low-energetic and energetic phase shifts in rats' liver mitochondria. The content of lipid peroxidation products of the above organellas varied analogously. The time following intoxication being longer, higher were the general level of liver mitochondria energetic activity and the content of lipid peroxidation products. The highest level was recorded on the 3d day after benzen-induced intoxication. On the 16th day complete recovery of liver mitochondria was not recorded.
Trifonov
Iu A
IuA
Turdyev
A A
AA
Tiunov
L A
LA
Ivanov
V I
VI
Voloshin
S V
SV
D000208:Acute Disease; D000818:Animals; D001554:Benzene / Q000506:poisoning*; D015227:Lipid Peroxidation; D008297:Male; D008930:Mitochondria, Liver / Q000378:metabolism*; D010085:Oxidative Phosphorylation; D051381:Rats
D001554:Benzene
Okislitel'noe fosforilirovanie i perekisnoe okislenie lipidov mitokhondriĭ pecheni krys posle ostroĭ benzol'noĭ intoksikatsii.