title: Urinary free cortisol output and disruptive behavior in children.
abstract: Hostile, impulsive, and aggressive behaviors have been associated with decreased urinary free cortisol (UFC) output. This is the first study to assess 24-hour UFC output in disruptive behavior disorders. The UFC of 19 boys with attention deficit and/or conduct disorder was compared with that of 19 age, race, and IQ matched normal controls studied as inpatients. Continuous Performance Test scores showed greater impulsivity in the disruptive group. UFC output did not differ between groups. However, UFC and difficulty were positively correlated on the continuous performance test in the form of longer interstimulus intervals and longer reaction times.
authors.forename: M J
authors.initials: MJ
authors.lastname: Kruesi
authors.forename: M E
authors.initials: ME
authors.lastname: Schmidt
authors.forename: M
authors.initials: M
authors.lastname: Donnelly
authors.forename: E D
authors.initials: ED
authors.lastname: Hibbs
authors.forename: S D
authors.initials: SD
authors.lastname: Hamburger
mesh_terms: D000293:Adolescent; D001143:Arousal / Q000502:physiology*; D001289:Attention Deficit Disorder with Hyperactivity / Q000652:urine*; D002648:Child; D002653:Child Behavior Disorders / Q000652:urine*; D006801:Humans; D006854:Hydrocortisone / Q000652:urine*; D008297:Male
chemical_list: D006854:Hydrocortisone