[Therapeutic analysis of autopsy findings in oral cancer].
Thirty-four autopsied patients with oral squamous cell carcinoma were analyzed by multiple regression analysis. The following results were obtained. 1) The suggested metastatic spread was from the highest count of oral cancer patients with metastases in lung to lower key organs, reflecting the cascade theory. 2) Multiple regression analysis revealed that local recurrence was significantly related to the treatment method, indicating that multidisciplinary treatment would be needed. 3) Multiple regression analysis indicated that mediastinal lymph node metastasis was significantly related to both the age of the patient and the stage of cancer development. 4) Multiple regression analysis showed that distant metastasis was significantly related to both the stage and the spleen weight. 5) There were many patients with the pulmonary metastases undergoing irradiation which ranged from 40Gy to 60Gy on the primary tumor. 6) Results showed that immunotherapy tended to control pulmonary metastases.
Fukazawa
H
H
2nd Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Iwate Medical University.
Sekiyama
S
S
Yuhki
K
K
Hoshi
H
H
Yagawa
K
K
Suzuki
A
A
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001344:Autopsy; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology* / Q000628:therapy; D012044:Regression Analysis