title: [A radioindicator method of determining the activity of pancreatic lipase in the body].
abstract: 125I-p-iodophenyllaurate proved to be a suitable substrate of lipase for studies of pancreas lipolytic function in vivo and in vitro. After peroral administration into rats the drug was hydrolyzed by lipase. The liberated 125I-p-iodophenol was absorbed in intestine and excreted with urine either as free 125I-p-iodophenol or its conjugates. Activity of pancreatic lipase was measured on the basis of radioactivity estimation of urine per min.
authors.forename: I N
authors.initials: IN
authors.lastname: Kendysh
authors.forename: V A
authors.initials: VA
authors.lastname: Brattsev
authors.forename: T V
authors.initials: TV
authors.lastname: Klimova
authors.forename: A I
authors.initials: AI
authors.lastname: Klimova
mesh_terms: D000818:Animals; D007457:Iodine Radioisotopes; D007850:Lauric Acids; D008049:Lipase / Q000032:analysis*; D010179:Pancreas / Q000201:enzymology*; D051381:Rats; D014304:Triolein / Q000652:urine
chemical_list: D007457:Iodine Radioisotopes; D007850:Lauric Acids; C060202:4-iodophenyllaurate; D014304:Triolein; D008049:Lipase
vernacular_title: Radioindikatorynyĭ metod opredeleniia aktivnosti pankreaticheskoĭ lipazy v organizme.