[Reactions of the ciliated epithelium of the respiratory tract to intubation anesthesia].
During insufflation anaesthesia the ciliary beat frequency of the ciliated cells of the trachea and the nasal cavity was assessed via vital cytological sampling from these sites before and after anaesthesia. The percentage of vital and dead ciliated cells as well as the percentage of squamous cells was counted in a chamber.-It was found that the ciliary beat frequency did not change significantly, whereas the number of vital ciliated cells in the tracheal samples was significantly reduced and the vitality of the epithelia in the nose showed a minor change. It must be presumed that the observed noxious effects on the tracheal epithelium are due to inhaled gases, since the temperature and humidity in the ventilation circuit are within a range known not to violate the ciliary epithelium. Apart from that, the intubation itself might produce reflexes in the mucosal layer.
Phadhana-anek
S
S
Universitäts-HNO-Klinik, Westfälischen Wilhelms, Universität, Münster.
Anger
C
C
von Bömmel
T
T
Deitmer
T
T
D000770:Anesthesia, Endotracheal; D000769:Anesthesia, Inhalation; D002452:Cell Count / Q000187:drug effects; D002908:Chronic Disease; D002923:Cilia / Q000187:drug effects; D002925:Ciliary Motility Disorders / Q000139:chemically induced*; D004737:Enflurane / Q000009:adverse effects; D004848:Epithelium / Q000187:drug effects; D006801:Humans; D007530:Isoflurane / Q000009:adverse effects; D010033:Otitis Media / Q000601:surgery; D010039:Otorhinolaryngologic Neoplasms / Q000601:surgery
D004737:Enflurane; D007530:Isoflurane
Die Reaktionen des Flimmerepithels des Respirationstraktes auf eine Intubationsnarkose.