title: [Study on the kinetics of isolation of trypsin immobilized on dialdehyde cellulose during hydrolytic destruction].
abstract: The kinetics of isolation of trypsin immobilized on a dialdehyde cellulose carrier in buffer solutions with pH 7.0 and 8.0 was studied. The number of the aldehyde groups amounted to 15-60 per cent of the initial one. The kinetics of hydrolytic destruction of the collected samples with the immobilized trypsin and the carrier in buffer solutions with pH 7.0 and 8.0 was also studied. The constants of the rates of trypsin isolation from the materials and the constants of the rates of liberation into the buffer solutions of the compounds containing CO-groups were determined. The groups were used for estimating hydrolytic destruction of the materials and the time of complete destruction of the materials in the solutions.
authors.forename: V V
authors.initials: VV
authors.lastname: Ryl'tsev
authors.forename: R B
authors.initials: RB
authors.lastname: Virnik
mesh_terms: D002482:Cellulose / Q000031:analogs & derivatives*; D004800:Enzymes, Immobilized / Q000302:isolation & purification* / Q000493:pharmacokinetics; D006868:Hydrolysis; D014677:Pharmaceutical Vehicles; D014357:Trypsin / Q000302:isolation & purification* / Q000493:pharmacokinetics
chemical_list: D004800:Enzymes, Immobilized; D014677:Pharmaceutical Vehicles; D002482:Cellulose; C058684:2,3-dialdehydocellulose; D014357:Trypsin
vernacular_title: Issledovanie kinetiki vydeleniia tripsina, immobilizovannogo na dial'degidtselliuloze, pri gidroliticheskoĭ destruktsii.