Borrelia burgdorferi antibodies in multiple sclerosis patients.
Lyme disease is said to produce a late syndrome resembling multiple sclerosis. We analyzed serum antibodies to Borrelia burgdorferi in 100 patients referred for possible MS. All lived in an area endemic for Lyme disease. Only 1 of 89 definite MS patients and 2 of 11 non-MS patients were antibody positive. Infection with Borrelia burgdorferi is rare in MS, and Lyme disease is unlikely to play a significant role in the differential diagnosis of MS.
Coyle
P K
PK
Department of Neurology, SUNY, Stony Brook 11794.
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000032:analysis* / Q000134:cerebrospinal fluid; D001898:Borrelia / Q000276:immunology*; D005260:Female; D006801:Humans; D008193:Lyme Disease / Q000150:complications / Q000188:drug therapy / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid / Q000150:complications / Q000276:immunology*
D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial