title: O-demethylation and N4-acetylation of sulfadimethoxine by the snail Cepaea hortensis.
abstract: The snail Cepaea hortensis O-dealkylates sulfadimethoxine at the 2- and 6-position, the 2-position being favoured. Sulfadimethoxine is also acetylated, while no measurable acetylation of the hydroxy (= demethyl) metabolites took place.
authors.forename: T B
authors.initials: TB
authors.lastname: Vree
authors.forename: M L
authors.initials: ML
authors.lastname: Vree
authors.forename: E W
authors.initials: EW
authors.lastname: Beneken Kolmer
authors.forename: Y A
authors.initials: YA
authors.lastname: Hekster
authors.forename: M
authors.initials: M
authors.lastname: Shimoda
authors.forename: J F
authors.initials: JF
authors.lastname: Nouws
authors.forename: T
authors.initials: T
authors.lastname: Yoshioka
authors.forename: K
authors.initials: K
authors.lastname: Hoji
mesh_terms: D000107:Acetylation; D000818:Animals; D003640:Dealkylation; D012908:Snails / Q000378:metabolism*; D013412:Sulfadimethoxine / Q000493:pharmacokinetics*
chemical_list: D013412:Sulfadimethoxine