title: Conditioned taste aversion in humans using motion-induced sickness as the US.
abstract: The purpose of the experiment was to demonstrate conditioned taste aversion (CTA) and latent inhibition (LI) of CTA in humans using rotation-induced motion sickness as the unconditioned stimulus. To accomplish this, flavour familiarity (familiar vs unfamiliar) and rotation (rotation vs no rotation) were manipulated in a 2 X 2 factorial design. Subjects consumed either a familiarly flavoured carbonated beverage or a novel one after which half of each group was rotated or not rotated. Two hours later the subjects were re-presented with the flavoured drink that they had previously drunk. The groups receiving rotation consumed less of the drink that the non-rotated groups, thus demonstrating CTA. The rotated group pre-exposed to the novel flavoured drink consumed less than the rotated group pre-exposed to the familiar drink, thus demonstrating LI. The effectiveness of the rotation procedure in producing motion sickness was confirmed by self-reports of general feelings and by symptom rating scales. In addition, it was found that, at the time of consuming the test drink the rotation groups' motion-sickness symptom scores were reduced to the level of the nonrotated groups. Applications of these data to the prophylactic treatment of chemotherapy-induced food aversions were discussed.
authors.forename: S
authors.initials: S
authors.lastname: Arwas
authors.forename: A
authors.initials: A
authors.lastname: Rolnick
authors.forename: R E
authors.initials: RE
authors.lastname: Lubow
mesh_terms: D000293:Adolescent; D000328:Adult; D003214:Conditioning, Classical; D006801:Humans; D008297:Male; D009041:Motion Sickness / Q000523:psychology*; D012399:Rotation; D013649:Taste