title: The cerebral vasculature in dementia pugilistica.
abstract: The brains of 22 ex-boxers were examined histologically to determine the frequency of recent or old haemorrhage. Four boxers had died from an acute intracerebral bleed, usually soon after a boxing bout. Seven of the other 18 showed evidence of previous perivascular haemorrhage, as detected by Perls' ferrocyanide test for iron, and a similar number showed minor degrees of meningeal or subpial siderosis, consistent with previous meningeal bleeding; cerebellar siderosis was present in six cases. Seventeen of the 22 boxers showed evidence of recent or past haemorrhage. Control material showed an incidence of 11% for perivascular iron deposition and only 4% for minor degrees of meningeal siderosis.
authors.affiliation: Department of Neuropathology, Runwell Hospital, Wickford, Essex, UK.
authors.forename: C W
authors.initials: CW
authors.lastname: Adams
authors.forename: C J
authors.initials: CJ
authors.lastname: Bruton
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001265:Athletic Injuries / Q000150:complications / Q000473:pathology*; D001914:Boxing; D001930:Brain Injuries / Q000150:complications / Q000473:pathology*; D002543:Cerebral Hemorrhage / Q000473:pathology*; D012090:Cumulative Trauma Disorders / Q000473:pathology*; D003704:Dementia / Q000209:etiology / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged