title: [Possible decontamination of pancreatin with gamma rays and chemical agents].
abstract: Certain pre-conditions given, the microbial contamination of pancreatin in powder form can be reduced below international standard values. However, each of the methods whether physical or chemical, causes a variable loss of activity depending on the methods applied and the concentration of the decontaminating agent used. Therefore during preparation of this complex enzymatic compound, highly aseptic conditions must be kept in all stages of the process to avoid an increase of germal contamination. For a final toxicological assessment of the decontaminated products, further tests are required.
authors.affiliation: Institut für Allgemeine und Kommunale Hygiene der Medizinischen Akademie Erfurt.
authors.forename: V
authors.initials: V
authors.lastname: Herzog
authors.forename: A
authors.initials: A
authors.lastname: Günther
authors.forename: M
authors.initials: M
authors.lastname: Meyer
authors.forename: B
authors.initials: B
authors.lastname: Belger
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004202:Disinfectants; D004340:Drug Contamination; D004586:Electrophoresis; D005027:Ethylene Oxide; D005557:Formaldehyde; D005720:Gamma Rays; D010194:Pancreatin / Q000032:analysis / Q000528:radiation effects*; D010463:Peracetic Acid; D011420:Propiolactone; D013242:Sterilization
chemical_list: D004202:Disinfectants; D005557:Formaldehyde; D011420:Propiolactone; D010194:Pancreatin; D010463:Peracetic Acid; D005027:Ethylene Oxide
vernacular_title: Möglichkeiten der Dekontamination von Pankreatin mit gamma-Strahlen und chemischen Mitteln.