title: Serum Tamm-Horsfall protein levels in childhood: relationship with age and glomerular filtration rate.
abstract: Serum Tamm-Horsfall protein (THP) levels were measured in 157 infants and children, 46 cord blood samples and 75 adults using an enzyme-linked immunosorbent assay. THP levels increased significantly across the age groups, suggesting a positive relationship with age. There was a strong positive relationship between serum THP and estimated glomerular filtration rate among children with chronic renal failure.
authors.affiliation: Department of Child Health, Royal Infirmary, Cardiff, UK.
authors.forename: M
authors.initials: M
authors.lastname: Alfaham
authors.forename: T J
authors.initials: TJ
authors.lastname: Peters
authors.forename: S
authors.initials: S
authors.lastname: Meyrick
authors.forename: P
authors.initials: P
authors.lastname: Avis
authors.forename: K
authors.initials: K
authors.lastname: Verrier Jones
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D005919:Glomerular Filtration Rate; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000503:physiopathology / Q000652:urine; D009088:Mucoproteins / Q000097:blood* / Q000502:physiology / Q000652:urine; D058949:Uromodulin
chemical_list: D009088:Mucoproteins; C548612:UMOD protein, human; D058949:Uromodulin