title: Severe microvascular disease in type II diabetes of early onset. A family study.
abstract: Both early onset and late onset type II diabetes were present in one family of nine siblings. The three early onset type II diabetic siblings showed severe microvascular complications: proliferative retinopathy, diabetic nephropathy, and peripheral neuropathy. Early onset type II diabetes was not associated with any particular HLA haplotype. Early onset type II diabetes could be considered a clinical and genetic disease entity different from MODY type diabetes.
authors.affiliation: Cattedra di Patologia Medica, Università di Brescia, II Divisione di Medicina, Spedali di Brescia, Italy.
authors.forename: T
authors.initials: T
authors.lastname: Scalvini
authors.forename: S
authors.initials: S
authors.lastname: Spandrio
authors.forename: O
authors.initials: O
authors.lastname: di Stefano
authors.forename: M C
authors.initials: MC
authors.lastname: Cotelli
authors.forename: G
authors.initials: G
authors.lastname: Carella
authors.forename: G P
authors.initials: GP
authors.lastname: Balestrieri
mesh_terms: D000328:Adult; D002096:C-Peptide / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000235:genetics*; D003925:Diabetic Angiopathies / Q000097:blood / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree
chemical_list: D002096:C-Peptide