Six new isolates of human immunodeficiency virus type 2 (HIV-2) and the molecular characterization of one (HIV-2CAM2).
We report the isolation of human immunodeficiency virus type 2 (HIV-2) from each of six West Africans with AIDS-related complex or AIDS. One isolate (HIV-2CAM2) was molecularly cloned and shown by restriction mapping to differ in seven out of 22 sites from the prototype HIV-2ROD. Nevertheless, by a number of serological criteria these isolates are all clearly HIV-2.
Tristem
M
M
Department of Haematological Medicine, University of Cambridge Clinical School, U.K.
Mansinho
K
K
Champalimaud
J L
JL
Ayres
L
L
Karpas
A
A
D000386:AIDS-Related Complex / Q000382:microbiology; D000163:Acquired Immunodeficiency Syndrome / Q000382:microbiology; D015139:Blotting, Southern; D004279:DNA, Viral / Q000235:genetics; D006169:Guinea-Bissau / Q000208:ethnology; D015483:HIV Antibodies / Q000032:analysis; D015488:HIV Antigens / Q000032:analysis; D015498:HIV-2 / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D015183:Restriction Mapping
D004279:DNA, Viral; D015483:HIV Antibodies; D015488:HIV Antigens