title: Rug shampoo and Kawasaki disease.
abstract: Following personal interviews with 63 families of children with Kawasaki disease and with 63 control families with children paired for race, sex, and age, no epidemiologic differences were seen except for use of rug shampoo within 1 month of onset in 16 episodes in 15 children with Kawasaki disease in 14 families (24% of children, 22% of families) compared with two families of control children (3%, P less than .005). Explanations for this strong association of recent rug shampoo and Kawasaki disease include the question of recall bias as well as the possibility that an agent in the shampooing process does cause or does contribute to illness.
authors.affiliation: Division of Pediatric Cardiology, New York Hospital-Cornell University Medical Center, New York 10021.
authors.forename: N S
authors.initials: NS
authors.lastname: Fatica
authors.forename: F
authors.initials: F
authors.lastname: Ichida
authors.forename: M A
authors.initials: MA
authors.lastname: Engle
authors.forename: M L
authors.initials: ML
authors.lastname: Lesser
mesh_terms: D000485:Allergens / Q000276:immunology; D000818:Animals; D039741:Antigens, Dermatophagoides; D002648:Child; D002675:Child, Preschool; D003902:Detergents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008925:Mites / Q000276:immunology; D009080:Mucocutaneous Lymph Node Syndrome / Q000453:epidemiology* / Q000209:etiology; D012307:Risk Factors; D013501:Surface-Active Agents / Q000009:adverse effects*
chemical_list: D000485:Allergens; D039741:Antigens, Dermatophagoides; D003902:Detergents; D013501:Surface-Active Agents