title: Sickle cell anemia and mitral valve replacement. Case report.
abstract: An 8-year-old black boy with sickle cell disease and severe hemolytic anemia crisis (95% hemoglobin S) also had mitral incompetence due to rheumatic valve disease. A 27 mm monostrut Björk-Shiley valve prosthesis was implanted after partial exchange transfusions had reduced the hemoglobin S to less than 40%. High-flow normothermic perfusion was used during extracorporeal circulation, with care taken to avoid hypoxia and acidosis. Postoperative recovery was uneventful.
authors.affiliation: Hospital dos Servidores do Estado, Rio de Janeiro, Brazil.
authors.forename: V
authors.initials: V
authors.lastname: Bomfim
authors.forename: A
authors.initials: A
authors.lastname: Ribeiro
authors.forename: F
authors.initials: F
authors.lastname: Gouvea
authors.forename: J
authors.initials: J
authors.lastname: Pereira
authors.forename: V
authors.initials: V
authors.lastname: Björk
mesh_terms: D000755:Anemia, Sickle Cell / Q000097:blood / Q000150:complications*; D002648:Child; D015150:Echocardiography, Doppler; D005078:Exchange Transfusion, Whole Blood; D006350:Heart Valve Prosthesis; D006451:Hemoglobin, Sickle / Q000032:analysis; D006801:Humans; D008297:Male; D008943:Mitral Valve; D008944:Mitral Valve Insufficiency / Q000097:blood / Q000150:complications / Q000601:surgery*
chemical_list: D006451:Hemoglobin, Sickle