Interaction at clinical level between erythrocyte acid phosphatase and adenosine deaminase genetic polymorphisms.
The effects of ACP1 phenotype on birth weight, neonatal jaundice, and obesity in children are dependent on ADA genotype. These phenomena may represent a clinical counterpart of the in vitro biochemical interactions between the two systems recently observed by our group.
Gloria-Bottini
F
F
Division of Biometry and Human Development, 2nd University of Rome, School of Medicine, Italy.
Lucarelli
P
P
Amante
A
A
Lucarini
N
N
Finocchi
G
G
Bottini
E
E
D000135:Acid Phosphatase / Q000097:blood / Q000235:genetics*; D000243:Adenosine Deaminase / Q000097:blood / Q000235:genetics*; D004912:Erythrocytes / Q000201:enzymology*; D005838:Genotype; D006801:Humans; D007231:Infant, Newborn; D007567:Jaundice, Neonatal / Q000235:genetics; D009700:Nucleoside Deaminases / Q000235:genetics*; D009765:Obesity / Q000235:genetics; D011110:Polymorphism, Genetic; D012307:Risk Factors
D000135:Acid Phosphatase; D009700:Nucleoside Deaminases; D000243:Adenosine Deaminase