title: Double minutes in two primary adenocarcinomas of the prostate.
abstract: Double minute chromosomes were found in metaphases from short-term tissue cultures of two primary prostatic adenocarcinomas. This is the first cytogenetic evidence of gene amplification in this tumor type.
authors.affiliation: Department of Clinical Genetics, University Hospital, Lund, Sweden.
authors.forename: J
authors.initials: J
authors.lastname: Limon
authors.forename: R
authors.initials: R
authors.lastname: Lundgren
authors.forename: P
authors.initials: P
authors.lastname: Elfving
authors.forename: S
authors.initials: S
authors.lastname: Heim
authors.forename: U
authors.initials: U
authors.lastname: Kristoffersson
authors.forename: N
authors.initials: N
authors.lastname: Mandahl
authors.forename: F
authors.initials: F
authors.lastname: Mitelman
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics*; D000368:Aged; D002869:Chromosome Aberrations; D005784:Gene Amplification; D006801:Humans; D007621:Karyotyping; D008297:Male; D008677:Metaphase; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000235:genetics*