ER-D5 antigen in breast cancer.
We measured an estrogen-receptor-associated protein (ER-D5), estrogen and progesterone receptors (ER; PgR) in samples obtained from 28 female patients with primary breast carcinoma. A correlation of r = 0.79 was found between ER-D5 and ER values and between ER-D5 and PgR values in premenopausal woman. In postmenopausal women a correlation (r = 0.75) was found only between ER-D5 and ER and not between ER-D5 and PgR. The measurement of this cytosolic protein may be a complementary tool in the management of breast cancer.
Navarro
M A
MA
Hormone Unit (Biochemistry Service), Hospital de Bellvitge, Barcelona, Spain.
Guardia
M
M
Arranz
B
B
Bonnin
M R
MR
Rosel
P
P
D000941:Antigens / Q000032:analysis; D001943:Breast Neoplasms / Q000032:analysis*; D002352:Carrier Proteins / Q000032:analysis*; D005260:Female; D006801:Humans; D011960:Receptors, Estrogen / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis
D000941:Antigens; D002352:Carrier Proteins; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; C010140:estrophilin