title: Osseointegrated knee prostheses. An experimental study in rabbits.
abstract: Osseointegration, defined as direct bone-to-implant contact, has been suggested as an approach for improving the results of arthroplasties of the major joints. An experimental investigation in femoral-patellar joint of the rabbit was performed to evaluate whether osseointegration could be achieved in a one-stage surgical procedure. After three months, it was found that the screws used for anchorage of the prosthesis showed an average direct bone-to-implant contact of 60% in three selected consecutive threads on each side. The range was 40-90%. These figures correspond well with previously reported ones from bone anchored titanium fixtures. It was therefore concluded that osseointegration of dynamically loaded screws used for anchorage of a femoral-patellar joint prosthesis may be achieved in spite of the fact that no controlled healing period for the screws was observed.
authors.affiliation: Orthopaedic Clinic, Mölndal Hospital, University of Göteborg, Sweden.
authors.forename: T
authors.initials: T
authors.lastname: Röstlund
authors.forename: L
authors.initials: L
authors.lastname: Carlsson
authors.forename: B
authors.initials: B
authors.lastname: Albrektsson
authors.forename: T
authors.initials: T
authors.lastname: Albrektsson
mesh_terms: D000818:Animals; D001863:Bone Screws; D007719:Knee Joint / Q000033:anatomy & histology / Q000601:surgery; D007720:Knee Prosthesis; D008722:Methods; D011817:Rabbits; D014025:Titanium
chemical_list: D014025:Titanium