title: Tendinous laxity and Jaccoud's syndrome in patients with systemic lupus erythematosus. Possible role of secondary hyperparathyroidism.
abstract: Fourteen of 52 unselected patients with systemic lupus erythematosus (SLE) (27%) had ligamentous derangement demonstrated by either Jaccoud's syndrome and/or patellar tendon elongation. Three cases had only Jaccoud's syndrome, 4 isolated patellar tendinous laxity, while the remaining 7 presented both findings. Jaccoud's syndrome and/or tendinous laxity were not associated to an increased frequency of arthritis, corticosteroid therapy or a longer disease duration, but significantly associated with increased serum PTH levels secondary to chronic renal failure. Hyperparathyroidism secondary to chronic renal failure should, therefore, be considered a potential factor contributing to the development of Jaccoud's syndrome and/or tendinous laxity in patients with SLE.
authors.affiliation: Section of Rheumatology, Instituto Nacional de Rehabilitación, Buenos Aires, Argentina.
authors.forename: S M
authors.initials: SM
authors.lastname: Babini
authors.forename: J A
authors.initials: JA
authors.lastname: Cocco
authors.forename: M
authors.initials: M
authors.lastname: de la Sota
authors.forename: J C
authors.initials: JC
authors.lastname: Babini
authors.forename: A
authors.initials: A
authors.lastname: Arturi
authors.forename: J C
authors.initials: JC
authors.lastname: Marcos
authors.forename: O G
authors.initials: OG
authors.lastname: Morteo
mesh_terms: D000293:Adolescent; D000328:Adult; D001168:Arthritis / Q000503:physiopathology*; D002118:Calcium / Q000097:blood; D002648:Child; D003404:Creatinine / Q000652:urine; D005260:Female; D005532:Foot Deformities, Congenital; D006228:Hand Deformities, Congenital; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000503:physiopathology*; D007593:Joint Instability / Q000503:physiopathology*; D007719:Knee Joint / Q000503:physiopathology; D008180:Lupus Erythematosus, Systemic / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000097:blood; D010758:Phosphorus / Q000097:blood; D013710:Tendons / Q000503:physiopathology*; D014527:Uric Acid / Q000097:blood
chemical_list: D010281:Parathyroid Hormone; D014527:Uric Acid; D010758:Phosphorus; D003404:Creatinine; D002118:Calcium