Clinical and experimental studies on a midgut carcinoid tumor.
This study reports on a patient with a midgut carcinoid discovered due to the occurrence of a subcutaneous metastasis that caused symptoms. The histopathologic diagnosis of a carcinoid was confirmed by light and electron microscopic and immunocytochemical examination of the metastasis. The primary ileal tumors were only localized after the determination of serotonin in platelet-poor plasma/whole blood sampled at selective mesenteric vein catheterization. Tumor cells from lymph node metastases were studied in vitro, in intraocular heterotransplants, and in cell culture.
Ahlund
L
L
Department of Surgery I, Gothenburg University, Göteborg, Sweden.
Kindblom
L G
LG
Nilsson
O
O
Skolnik
G
G
Tylén
U
U
Dahlström
A
A
Ahlman
H
H
D000818:Animals; D002276:Carcinoid Tumor / Q000378:metabolism / Q000473:pathology / Q000556:secondary*; D005260:Female; D006801:Humans; D007078:Ileal Neoplasms / Q000473:pathology*; D008854:Microscopy, Electron; D008875:Middle Aged; D009368:Neoplasm Transplantation; D051381:Rats; D012701:Serotonin / Q000097:blood; D012878:Skin Neoplasms / Q000556:secondary*; D014407:Tumor Cells, Cultured
D012701:Serotonin