title: [Action and biocompatibility of two collagen-based hemostatics in animal experiments].
abstract: Efficacy and biocompatibility of two collagen hemostatic wound dressings (usual agent: Collastypt, fluid-stabilised agent: Lyostypt) were compared. In a prospective randomized study the local hemostatic effect (bleeding time and blood loss) of the two agents were investigated after liver trauma of 45 rats. Liver wounds which remained untreated served as controls. Both preparations significantly reduced bleeding. The fluid-stabilised agent was significantly superior to the second collagen agent of different manufacturing.
authors.affiliation: Biochemische und Experimentelle Abteilung des II. Chirurgischen, Lehrstuhls, der Universität zu Köln.
authors.forename: G H
authors.initials: GH
authors.lastname: Engelhardt
authors.forename: H J
authors.initials: HJ
authors.lastname: Gerhardt
authors.forename: M
authors.initials: M
authors.lastname: Nagelschmidt
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001684:Biological Dressings; D003094:Collagen / Q000494:pharmacology*; D006490:Hemostatics; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D001672:Biocompatible Materials; D006490:Hemostatics; D003094:Collagen
vernacular_title: Wirksamkeit und Biokompatibilität zweier Hämostyptika auf Kollagen-Basis im Tierexperiment.