[Experimental validation of the expediency of the use of ultra-high frequency therapy in combination with antibacterial drugs in infiltrative tuberculosis of the lungs].
The influence of the U.H.F. electric field in combination with specific antibacterial therapy on the character of morphological shifts, isoniazid accumulation, collagen fractional composition and tubercle bacilli population in the foci of infiltrative tuberculosis of the lungs was studied experimentally. The effect of this preformed physical factor on the process of tuberculosis was shown to be favourable. Under the action of the U.H.F. electric field microcirculation in the lungs improved, and the levels of isoniazid accumulation in tuberculosis foci increased 1.9-fold leading to decreasing of mycobacterial populations. By restricting specific inflammation, the U.H.F. electric field prevented excessive collagen formation.
Lomachenkov
V D
VD
Pavliunina
L D
LD
Bazhenov
S M
SM
Pavliunin
A M
AM
Zhamoĭdo
S V
SV
D000818:Animals; D000995:Antitubercular Agents / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D007538:Isoniazid / Q000493:pharmacokinetics / Q000627:therapeutic use; D008297:Male; D008833:Microcirculation; D011652:Pulmonary Circulation; D011817:Rabbits; D011846:Radio Waves; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000503:physiopathology / Q000628:therapy*
D000995:Antitubercular Agents; D007538:Isoniazid
Eksperimental'noe obosnovanie tselesobraznosti primeneniia UVCh-terapii v sochetanii s antibakterial'nymi preparatami pri infil'trativnom tuberkuleze legkikh.