Biological monitoring of toxic metals in urine by simultaneous inductively coupled plasma-atomic emission spectrometry.
A simple and rapid method for the simultaneous determination of 11 metals (As, Be, Cd, Co, Cr, Cu, Hg, Mn, Ni, Pb, and Zn) in urine by inductively coupled argon plasma-atomic emission spectrometry is presented. Acidification of the urine was the only sample preparation required. Background correction was applied to ensure accuracy. Analytical calibration was based on matrix matching using a "simulated urine" solution. Detection limits in the low mg/L range and linearity over three orders of magnitude were obtained for all 11 metals. In the Occupational Health Laboratory, this procedure has been applied for routine screening of workers for occupational exposure to toxic metals.
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Occupational Health Laboratory, Ontario Ministry of Labour, Weston, Canada.
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D002138:Calibration; D004781:Environmental Exposure; D004784:Environmental Monitoring / Q000379:methods*; D006801:Humans; D008670:Metals / Q000652:urine*; D013052:Spectrometry, X-Ray Emission / Q000379:methods* / Q000592:standards
D008670:Metals