[Probable allergy to polyvidon, responsible for a reaction to iodinated contrast medium: a case of asthma after hysterosalpingography].
A case of asthma induced by a iodinated medium (ICM) is reported. The ordinary ICM for urography were well tolerated. The suspected drug included polyvidon (PVP). Skin test, human basophil degranulation tests and leukocyte histamine release are negative for meglumine ioxitalamate, and positive for PVP. PVP is a macromolecule, used in different drugs, and as a clarifying agent of alcohols. An IgE-dependent allergy to PVP is postulated.
Moneret-Vautrin
D A
DA
Service de Médecine D, Immuno-Allergologie, CHU de Brabois Vandoeuvre-les-Nancy.
Mata
E
E
Gerard
H
H
Tréchot
M
M
D001249:Asthma / Q000209:etiology / Q000276:immunology*; D003287:Contrast Media / Q000276:immunology*; D004342:Drug Hypersensitivity / Q000209:etiology / Q000276:immunology*; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology; D008875:Middle Aged; D011205:Povidone / Q000276:immunology*; D012882:Skin Tests
D003287:Contrast Media; D011205:Povidone
Allergie probable à la polyvidone, responsable d'un accident à un produit iodé de contraste: à propos d'un cas d' asthme après hystérosalpingographie.