Thrombocytopenia--a rare but potentially serious side effect of initial daily and interrupted use of rifampicin.
Thrombocytopenia is occasionally caused by rifampicin, when high-doses are given twice-weekly. This complication is rare when the medication is given in small daily doses, or following a prolonged interruption of therapy. Two cases of rifampicin-induced thrombocytopenia are reported. One occurred within four days of the initiation of small daily doses and the other following a prolonged interruption of therapy.
Lee
C H
CH
Department of Chest Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China.
Lee
C J
CJ
D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012293:Rifampin / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D013921:Thrombocytopenia / Q000139:chemically induced*; D013997:Time Factors; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy
D012293:Rifampin