title: Perioperative complications following the use of vancomycin in children: a report of two cases.
abstract: We describe two patients in whom rapid administration of vancomycin caused severe hypotension. Possible mechanisms for this effect are discussed, with reference to the role of the anaesthetist as administrator of drugs prescribed by others. Recommendations are made on safe administration of vancomycin with respect to rate of infusion and possible interactions.
authors.affiliation: Department of Anaesthesia, Hospital for Sick Children, London.
authors.forename: C J
authors.initials: CJ
authors.lastname: Best
authors.forename: M
authors.initials: M
authors.lastname: Ewart
authors.forename: E
authors.initials: E
authors.lastname: Sumner
mesh_terms: D000758:Anesthesia; D002648:Child; D006801:Humans; D007022:Hypotension / Q000139:chemically induced*; D007223:Infant; D007431:Intraoperative Complications; D008297:Male; D013997:Time Factors; D014640:Vancomycin / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D014640:Vancomycin