title: Temporal aspects of accommodative adaptation.
abstract: Pre- and post-task measures of dark focus (DF) were used to assess accommodative adaptation induced by brief near-vision tasks in 10 late-onset myopes (LOM's) and 10 emmetropes. The degree of adaptation was examined after tasks of 15, 30, and 45 s duration. Accommodation was measured after the task at 1 s intervals over a 90 s period using an objective infrared optometer. Emmetropic subjects showed a significant increase in DF during the first 10 s of post-task recording, which regressed to the pre-task value within a further 20 to 30 s. No significant difference in post-task accommodative regression was observed after the three task durations. Similar findings were observed for LOM's after the 15 and 30 s tasks. However, after the 45 s task, LOM's exhibited a marked negative shift in DF during the 10 to 50 s post-task period. Instillation of a beta adrenergic antagonist attenuated this negative shift, suggesting that it was mediated via beta adrenergic innervation to the ciliary muscle.
authors.affiliation: Schnurmacher Institute for Vision Research, State College of Optometry, State University of New York, New York.
authors.forename: M
authors.initials: M
authors.lastname: Rosenfield
authors.forename: B
authors.initials: B
authors.lastname: Gilmartin
mesh_terms: D000065:Accommodation, Ocular / Q000187:drug effects; D000221:Adaptation, Ocular / Q000187:drug effects; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D009216:Myopia / Q000150:complications; D012030:Refractive Errors / Q000150:complications; D013997:Time Factors; D013999:Timolol / Q000627:therapeutic use
chemical_list: D013999:Timolol