title: Small intestinal perforation in Wegener's granulomatosis.
abstract: Wegener's granulomatosis is a disease characterized by necrotizing vasculitis and granulomatous inflammation. Gastrointestinal (GI) involvement is uncommon in this disorder. Only a few cases of perforation of GI tract have been reported, but vasculitis has not been demonstrated to be a cause of perforation in these cases. We report a case of Wegener's granulomatosis in which a single perforation in the terminal ileum was disclosed on laparotomy and active necrotizing vasculitis was found in the submucosal layer of the resected specimen.
authors.affiliation: First Department of Internal Medicine, Kagawa Medical School, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Tokuda
authors.forename: N
authors.initials: N
authors.lastname: Kurata
authors.forename: H
authors.initials: H
authors.lastname: Daikuhara
authors.forename: M
authors.initials: M
authors.lastname: Akisawa
authors.forename: I
authors.initials: I
authors.lastname: Onishi
authors.forename: T
authors.initials: T
authors.lastname: Asano
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: M
authors.initials: M
authors.lastname: Ohmori
authors.forename: S
authors.initials: S
authors.lastname: Irino
mesh_terms: D000328:Adult; D014890:Granulomatosis with Polyangiitis / Q000150:complications*; D006801:Humans; D007077:Ileal Diseases / Q000150:complications*; D007416:Intestinal Perforation / Q000150:complications*; D008297:Male; D014657:Vasculitis / Q000150:complications