Polyarteritis in a beagle.
A 13-month-old Beagle became anorectic and had fever, stiff gait, and tenderness in the inguinal region. Clinical signs of disease were associated with neutrophilia and a decrease in the albumin-to-globulin ratio. The dog became clinically normal for 5 days after 3 days of treatment with penicillin G and dihydrostreptomycin. Clinical signs of disease recurred, and the dog was euthanatized after failing to respond to administration of a trimethoprim-sulfamethoxazole combination for 9 days. Disseminated arteritis was seen in the testes, epididymides, mesentery, coronary arteries, aorta, and thyroid gland. Lesions were seen in large and medium-sized arteries and varied from acute necrotizing arteries to a chronic lesion with organization and recanalization of thrombi. The clinical signs of disease resembled those of Beagle pain syndrome, described in laboratory Beagles.
Albassam
M A
MA
Parke-Davis Research Institute, Warner-Lambert Canada Inc., Ontario, Canada.
Houston
B J
BJ
Greaves
P
P
Barsoum
N
N
D000818:Animals; D001158:Arteries / Q000473:pathology; D001167:Arteritis / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D008297:Male; D013737:Testis / Q000098:blood supply; D013961:Thyroid Gland / Q000098:blood supply