[Modeling of experimental hypertension by chronic salt loading combined with a low-protein diet in Wistar rats].
Combination of chronic salt loading with protein-poor diet produces experimental hypertension with natrium consumption near to physiological. The present model is characterized, compared to the existing one, by stage development, moderate arterial blood pressure elevation and absence of "salt toxicosis" and may be thus considered more adequate for experimental investigation of primary arterial hypertension pathophysiology.
Strekalova
V V
VV
Khachirov
D G
DG
Dedenkov
A N
AN
Suvorov
Iu I
IuI
Shvatsabaia
I K
IK
D000818:Animals; D004044:Dietary Proteins / Q000008:administration & dosage*; D004195:Disease Models, Animal; D006973:Hypertension / Q000209:etiology*; D008297:Male; D011488:Protein Deficiency / Q000150:complications*; D051381:Rats; D011919:Rats, Inbred Strains; D012965:Sodium Chloride / Q000008:administration & dosage / Q000009:adverse effects*; D013997:Time Factors
D004044:Dietary Proteins; D012965:Sodium Chloride
Modelirovanie eksperimental'noĭ gipertonii s pomoshch'iu khronicheskoĭ solevoĭ nagruzki v sochetanii s nizkobelkovoĭ dietoĭ u krys Vistar.