Thoracic disc herniation and paraplegia in Stickler's syndrome.
Stickler's syndrome, an autosomal dominant connective tissue disorder, is characterized by progressive ophthalmic, orofacial, and skeletal abnormalities. Epiphyseal dysplasia is seen in this syndrome and affects the spine, causing anterior vertebral body wedging and Schmorl's node formation. These spinal abnormalities are usually asymptomatic. We report here the first case of thoracic disc herniation and paraplegia associated with Stickler's syndrome.
Harkey
H L
HL
Department of Neurosurgery, University of Mississippi Medical Center, Jackson.
Cullom
E T
ET
Parent
A D
AD
D000293:Adolescent; D005128:Eye Diseases / Q000235:genetics*; D005260:Female; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000235:genetics* / Q000601:surgery; D007738:Kyphosis / Q000235:genetics*; D007796:Laminectomy; D008279:Magnetic Resonance Imaging; D010003:Osteoarthritis / Q000235:genetics*; D010243:Paralysis / Q000235:genetics* / Q000601:surgery; D013130:Spinal Stenosis / Q000235:genetics / Q000601:surgery; D013577:Syndrome; D013904:Thoracic Vertebrae / Q000002:abnormalities* / Q000601:surgery; D014057:Tomography, X-Ray Computed