Chromosomal localization of human glutathione transferase genes of classes alpha, mu and pi.
The numerous human glutathione transferases may be divided into three classes, mu, alpha and pi. Using a panel of human-rodent somatic cell hybrids and DNA probes specific for each of the three classes, we have mapped a class mu gene to chromosome 3, a class alpha gene to chromosome 6 and a class pi gene to chromosome 11. The two latter assignments confirm earlier reports, whereas the assignment of the class mu gene represents a new addition to the human gene map.
Islam
M Q
MQ
Department of Genetics, University of Göteborg, Sweden.
Platz
A
A
Szpirer
J
J
Szpirer
C
C
Levan
G
G
Mannervik
B
B
D000818:Animals; D015139:Blotting, Southern; D002874:Chromosome Mapping; D002880:Chromosomes, Human, Pair 11; D002893:Chromosomes, Human, Pair 3; D002896:Chromosomes, Human, Pair 6; D004247:DNA / Q000235:genetics; D015342:DNA Probes; D005982:Glutathione Transferase / Q000235:genetics*; D006801:Humans; D006822:Hybrid Cells; D051379:Mice; D051381:Rats
D015342:DNA Probes; D004247:DNA; D005982:Glutathione Transferase