[Combined reaction of the lymphoid organs and the adrenals to stress in mature animals subjected to cold in the early period of postnatal ontogeny].
Structural-functional organization of the lymphoid organs and functional state of the adrenals have been studied in animals, subjected to cold in early postnatal period, as well as changes of the parameters mentioned to a short and prolonged cooling in mature rats. For the animals increase in the thymus mass and in reproduction rate of lymphocytes in the thymus, spleen and lymph nodes is specific against the background of high corticosteroid secretion. When the control animals are kept in cold for a long time, after the phase of an acute stress, accompanied with hypercorticism and a pronounced lymphatic effect, during the period of an increased cold stability, the high secretion of glucocorticoid hormones is accompanied with a certain activation of thymus-dependent zones in the peripheral lymphoid organs. In the mature rats, subjected to cold at early ontogenesis both stress-reaction to cooling and rearrangement in the regulatory systems studied does not develop at adaptation to cold.
Borodin
Iu I
IuI
Sedova
L A
LA
Seliatitskaia
V G
VG
Shorin
Iu P
IuP
D000222:Adaptation, Physiological; D000311:Adrenal Glands / Q000254:growth & development / Q000473:pathology*; D000375:Aging / Q000473:pathology*; D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development*; D003080:Cold Temperature / Q000009:adverse effects*; D003345:Corticosterone / Q000097:blood; D008221:Lymphoid Tissue / Q000254:growth & development / Q000473:pathology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000254:growth & development / Q000473:pathology; D013312:Stress, Physiological / Q000473:pathology*; D013950:Thymus Gland / Q000254:growth & development / Q000473:pathology
D003345:Corticosterone
Sochetannaia reaktsiia limfoidnykh organov i nadpochechnikov na stress u vzroslykh zhivotnykh, ispytavshikh vozdeĭstvie kholodom v rannem periode postnatal'nogo ontogeneza.