title: In situ hybridization localizes the human type II alpha 1 collagen gene (COL2A1) to 12q13.
abstract: We have, using in situ hybridization technique, localized the human type II alpha 1 collagen gene (COL2A1) to chromosome band 12q13. The gene had previously been assigned to either 12q13.1-13.2 or 12q14.3. Since the chromosome segment 12q13-15 has been shown to be rearranged in several benign and malignant human neoplasms, the exact band localization of COL2A1 within this region makes it a useful marker for the molecular analysis of these tumors.
authors.forename: K
authors.initials: K
authors.lastname: Arheden
authors.forename: N
authors.initials: N
authors.lastname: Mandahl
authors.forename: S
authors.initials: S
authors.lastname: Heim
authors.forename: F
authors.initials: F
authors.lastname: Mitelman
mesh_terms: D002874:Chromosome Mapping; D002881:Chromosomes, Human, Pair 12; D003094:Collagen / Q000235:genetics*; D005796:Genes; D006801:Humans; D005810:Multigene Family; D009693:Nucleic Acid Hybridization
chemical_list: D003094:Collagen