title: The hypo-osmotic swelling test and the sperm mucus penetration test in determining fertilization of the human oocyte.
abstract: The usefulness of the hypo-osmotic swelling (HOS) test and the sperm mucus penetration (SMP) test as sperm function tests for in-vitro fertilization was analysed in 56 couples. Using logistic regression analysis only the SMP test was independently related to fertilization (P = 0.004), no false negative results were obtained, i.e. no fertilization if sperm from the ejaculate failed to penetrate mucus. The HOS test was of no predictive value. The results justify a further examination of the SMP test in other IVF centres.
authors.affiliation: Harris Birthright Centre for Reproductive Medicine, Department of Obstetrics and Gynaecology, University of Sheffield, Jessop Hospital for Women, UK.
authors.forename: C L
authors.initials: CL
authors.lastname: Barratt
authors.forename: J C
authors.initials: JC
authors.lastname: Osborn
authors.forename: P E
authors.initials: PE
authors.lastname: Harrison
authors.forename: N
authors.initials: N
authors.lastname: Monks
authors.forename: B C
authors.initials: BC
authors.lastname: Dunphy
authors.forename: E A
authors.initials: EA
authors.lastname: Lenton
authors.forename: I D
authors.initials: ID
authors.lastname: Cooke
mesh_terms: D002582:Cervix Mucus; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008297:Male; D009865:Oocytes / Q000502:physiology*; D009994:Osmolar Concentration; D009997:Osmotic Pressure; D013094:Spermatozoa / Q000502:physiology*