[Features of ultrastructural changes of tumor cells in tissue culture under the effect of energy metabolism inhibitors].
It is shown that 2,4-dinitrophenol and dicyclohexylcarbodiimide, energy metabolism inhibitors, induce regular specific changes of the HeLa culture cells ultrastructure. Peculiarities of metabolism of the tumor cells as against the normal culture cells cause weaker and slower response.
Leĭkina
M I
MI
Drachuk
L P
LP
Poliakova
I A
IA
D019297:2,4-Dinitrophenol; D000818:Animals; D002234:Carbodiimides / Q000494:pharmacology*; D004024:Dicyclohexylcarbodiimide / Q000494:pharmacology*; D004140:Dinitrophenols / Q000494:pharmacology*; D004734:Energy Metabolism / Q000187:drug effects*; D006367:HeLa Cells; D006801:Humans; D013552:Swine; D014407:Tumor Cells, Cultured / Q000187:drug effects* / Q000648:ultrastructure; D014475:Uncoupling Agents / Q000494:pharmacology*
D002234:Carbodiimides; D004140:Dinitrophenols; D014475:Uncoupling Agents; D004024:Dicyclohexylcarbodiimide; D019297:2,4-Dinitrophenol
Osobennosti izmeneniĭ ul'trastruktury opukholevykh kletok v kul'ture tkaneĭ pri deĭstvii ingibitorov énergeticheskogo metabolizma.