title: Studies on the mechanism of action of Semecarpus anacardium in rheumatoid arthritis.
abstract: Semecarpus anacardium nuts are used for variety of disorders in Ayurveda. A chloroform extract of the nut significantly reduced acute carrageenan-induced paw oedema in rats and was active against the secondary lesions of adjuvant-induced arthritis. Delayed hypersensitivity induced in mice by sheep red blood cells as an antigen was potentiated by the extract.
authors.affiliation: College of Pharmacy, Shreemati Nathibai Damodar Thakarsi Women's University, Bombay, India.
authors.forename: M N
authors.initials: MN
authors.lastname: Saraf
authors.forename: R B
authors.initials: RB
authors.lastname: Ghooi
authors.forename: B K
authors.initials: BK
authors.lastname: Patwardhan
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001169:Arthritis, Experimental / Q000188:drug therapy / Q000503:physiopathology; D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000503:physiopathology; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D006968:Hypersensitivity, Delayed / Q000503:physiopathology; D007194:India; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000627:therapeutic use*; D010946:Plants, Medicinal / Q000032:analysis*
chemical_list: D000893:Anti-Inflammatory Agents; D010936:Plant Extracts