[Results of treatment of meningitis during a 10-year period].
A review of 131 cases of purulent meningitis is presented. The patients are mainly non-pediatric and, because of that, meningitis caused by Streptococcus pneumoniae predominates. This is the main reason for the high overall mortality of 15.6%. The main etiological cause of lethal meningitis was Streptococcus pneumoniae, and it is discussed whether chloramphenicol, previously shown to exert an antagonistic effect on beta-lactam antibiotics, contributes to the relatively high mortality. It is suggested that chloramphenicol should be withdrawn from meningitis treatment and replaced by cefuroxime.
Poulsgård
L
L
Buhl
M R
MR
D000328:Adult; D002444:Cefuroxime / Q000627:therapeutic use; D003718:Denmark; D006801:Humans; D008581:Meningitis / Q000188:drug therapy* / Q000382:microbiology / Q000401:mortality; D008875:Middle Aged; D011379:Prognosis; D013296:Streptococcus pneumoniae / Q000302:isolation & purification
D002444:Cefuroxime
Resultatet af 10 års meningitisbehandling.