[Familial incidence of gallstones].
From March 1986 to June 1988 ultrasound examinations for gallstones were performed on 1616 symptom-free persons (982 females and 634 males, aged 12-93 years). They were also asked about gallstones and (or) cholecystectomy among blood relatives. Gallstones were discovered or a previous cholecystectomy was reported in 316 persons (19.6%). The prevalence of gallstones was age-dependent and increased with age. Prevalence was higher in females than in males. There was, in this group of 316, a significant increase in family prevalence of gallstones among six of nine age-groups (P less than 0.05 and P less than 0.01, respectively) compared with those without gallstones. These data suggest a genetic disposition towards cholelithiasis, while dietary factors could not be definitely excluded.
Nürnberg
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D
Medizinische Klinik, Bezirkskrankenhaus Neuruppin, Humboldt-Universität, Berlin.
Berndt
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H
Pannwitz
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H
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002763:Cholecystectomy; D002769:Cholelithiasis / Q000453:epidemiology* / Q000235:genetics / Q000601:surgery; D003718:Denmark; D004032:Diet; D005260:Female; D005860:Germany, West; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012737:Sex Factors
Familiäre Häufung von Gallensteinen.