title: Transvesical phenol injection of pelvic nerve plexuses in females with refractory urge incontinence.
abstract: A series of 28 female patients with urge incontinence refractory to other forms of treatment underwent a total of 40 transvesical injections of phenol into the pelvic nerve plexuses. Following primary phenol injection only 8 patients (29%) had a significant response to therapy and all relapsed during follow-up. Only 3 of 11 patients undergoing a second injection had a clinical response to this therapy and 1 developed a vesicovaginal fistula. This suggests that phenol injections have little place in the management of urge incontinence and it is unwise to proceed to 2 or more injections because of the risk of fistula.
authors.affiliation: Department of Obstetrics and Gynaecology, St George's Hospital Medical School, London.
authors.forename: L L
authors.initials: LL
authors.lastname: Wall
authors.forename: S L
authors.initials: SL
authors.lastname: Stanton
mesh_terms: D000328:Adult; D000368:Aged; D003258:Consumer Behavior; D005260:Female; D006801:Humans; D007267:Injections; D008875:Middle Aged; D010388:Pelvis / Q000294:innervation; D010636:Phenols / Q000008:administration & dosage* / Q000009:adverse effects; D011379:Prognosis; D011788:Quality of Life; D014549:Urinary Incontinence / Q000188:drug therapy* / Q000523:psychology
chemical_list: D010636:Phenols