Anti-K1 of the IgA class associated with Morganella morganii infection.
An anti-K1 alloantibody developed in a patient infected with Morganella morganii. The serologic behavior and response to dithiothreitol initially suggested that the alloantibody was an IgM. However, flow cytometry and the separation of immunoglobulin classes by serum chromatography revealed that the anti-K1 was constituted solely of IgA. These data suggest that bacteria-induced red cell antibodies might be of the IgA class.
Pereira
A
A
Department of Hemotherapy and Hemostasis, Hospital Clínico, University of Barcelona, Spain.
Monteagudo
J
J
Rovira
M
M
Mazzara
R
R
Reverter
J C
JC
Castillo
R
R
D000368:Aged; D001789:Blood Group Antigens / Q000276:immunology*; D001787:Blood Group Incompatibility / Q000097:blood* / Q000209:etiology; D001788:Blood Grouping and Crossmatching; D002469:Cell Separation; D003298:Coombs Test; D004756:Enterobacteriaceae Infections / Q000097:blood* / Q000150:complications; D006801:Humans; D007070:Immunoglobulin A / Q000096:biosynthesis*; D007518:Isoantibodies / Q000096:biosynthesis*; D007626:Kell Blood-Group System / Q000276:immunology*; D008297:Male
D001789:Blood Group Antigens; D007070:Immunoglobulin A; D007518:Isoantibodies; D007626:Kell Blood-Group System