Suppression of lymphocyte blastogenesis by sera from calves transported by road.
The effect of sera from 4-h road-transported calves on mitogen-induced blastogenesis of bovine lymphocytes was investigated. Sera collected just after transportation showed a significant suppression (P less than 0.05) on blastogenesis. The immunosuppressive activity was reduced from those sera when they were treated with dextran-coated charcoal. Fractionation of the sera by ultrafiltration revealed that the activity was mainly concentrated in the fractions of molecular weights less than 50 kD.
Murata
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D000818:Animals; D002417:Cattle / Q000097:blood*; D008214:Lymphocytes / Q000502:physiology*; D008297:Male; D014186:Transportation