Combined sarcoidosis and disseminated visceral giant cell vasculitis.
A middle-aged man with only slight symptoms of disease of short duration died suddenly. On autopsy he was found to have not only disseminated visceral giant cell vasculitis with involvement of large and medium-sized arteries and veins, but also sarcoid granulomas in many organs, especially in enlarged mediastinal lymph nodes as well as in several vessel walls. Death was caused by myocardial infarction due to granulomatous vasculitis. This combination of diseases has not previously been described, and the question is whether it represents giant cell arteritis and sarcoidosis, separately, or whether it is a manifestation of a broad spectrum of the same disease.
Marcussen
N
N
Institute of Pathology, Centralsygehuset, Holstebro, Denmark.
Lund
C
C
D001167:Arteritis / Q000150:complications / Q000473:pathology; D006801:Humans; D007674:Kidney Diseases / Q000473:pathology*; D008171:Lung Diseases / Q000473:pathology*; D008297:Male; D008477:Mediastinal Diseases / Q000473:pathology*; D008875:Middle Aged; D012507:Sarcoidosis / Q000150:complications* / Q000473:pathology; D014657:Vasculitis / Q000150:complications* / Q000473:pathology