Small intestinal perforation in Wegener's granulomatosis.
Wegener's granulomatosis is a disease characterized by necrotizing vasculitis and granulomatous inflammation. Gastrointestinal (GI) involvement is uncommon in this disorder. Only a few cases of perforation of GI tract have been reported, but vasculitis has not been demonstrated to be a cause of perforation in these cases. We report a case of Wegener's granulomatosis in which a single perforation in the terminal ileum was disclosed on laparotomy and active necrotizing vasculitis was found in the submucosal layer of the resected specimen.
Tokuda
M
M
First Department of Internal Medicine, Kagawa Medical School, Japan.
Kurata
N
N
Daikuhara
H
H
Akisawa
M
M
Onishi
I
I
Asano
T
T
Kobayashi
S
S
Ohmori
M
M
Irino
S
S
D000328:Adult; D014890:Granulomatosis with Polyangiitis / Q000150:complications*; D006801:Humans; D007077:Ileal Diseases / Q000150:complications*; D007416:Intestinal Perforation / Q000150:complications*; D008297:Male; D014657:Vasculitis / Q000150:complications