Treatment-emergent depression with antidepressants in panic disorder.
Two patients with panic disorder received therapeutic doses of antidepressants. They developed endogenomorphic symptoms of major depression according to DSM-III-R criteria despite remission of their panic attacks. Treatment-emergent depression in panic disorder has been previously associated with high potency benzodiazepines. Whether antidepressant medications may unmask a depressive diathesis or are coincidentally associated with depression is discussed in this report.
Aronson
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TA
Department of Psychiatry and Behavioral Science, State University of New York Stony Brook 11794-8101.
D000379:Agoraphobia / Q000188:drug therapy*; D003866:Depressive Disorder / Q000139:chemically induced* / Q000188:drug therapy; D003891:Desipramine / Q000009:adverse effects* / Q000627:therapeutic use; D005239:Fear / Q000187:drug effects*; D005260:Female; D006801:Humans; D009661:Nortriptyline / Q000009:adverse effects* / Q000627:therapeutic use; D010200:Panic / Q000187:drug effects*; D010698:Phobic Disorders / Q000188:drug therapy*
D009661:Nortriptyline; D003891:Desipramine