title: A heteroploid permanent cell line originating from embryonic calf thyroid supporting the replication of all known bovine adenovirus serotypes.
abstract: An embryonic calf thyroid cell culture was established as a permanent heteroploid cell line, which is now in its 150th subculture. It allowed replication of all nine bovine adenovirus serotypes at its 15th as well as its 60-150th passages. All viruses induced typical cytopathic effects. Yields obtained on the permanent calf thyroid line were, on average, 0.8 log10 lower than those obtained on primary calf testicle cells.
authors.affiliation: Veterinary Medical Research Institute of the Hungarian Academy of Sciences, Budapest.
authors.forename: M
authors.initials: M
authors.lastname: Benkö
authors.forename: A
authors.initials: A
authors.lastname: Bartha
authors.forename: K
authors.initials: K
authors.lastname: Möstl
authors.forename: F
authors.initials: F
authors.lastname: Bürki
mesh_terms: D000256:Adenoviridae / Q000254:growth & development* / Q000502:physiology; D000818:Animals; D002417:Cattle; D002460:Cell Line; D003588:Cytopathogenic Effect, Viral; D007621:Karyotyping; D013961:Thyroid Gland / Q000166:cytology / Q000382:microbiology*; D014776:Virus Cultivation; D014779:Virus Replication