title: Neonatal endocarditis requiring surgery.
abstract: A case of infective endocarditis in a neonate is reported. Echocardiography demonstrated a large (1 X 1.5 cm) vegetation on the anterior mitral leaflet protruding into the ventricle during diastole. The left atrium was enlarged and Doppler showed mitral regurgitation. Excision of the vegetation during effective antibiotic treatment involved no complications. Although histologically the endocarditis was in the early stage of healing, surgical removal of large, floppy vegetations is advocated because of the unpredictable risk of catastrophic embolization.
authors.affiliation: Department of Pediatrics, University Hospital, Uppsala, Sweden.
authors.forename: L
authors.initials: L
authors.lastname: Charaf
authors.forename: M
authors.initials: M
authors.lastname: Hallberg
authors.forename: A
authors.initials: A
authors.lastname: Henze
mesh_terms: D000900:Anti-Bacterial Agents; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D015150:Echocardiography, Doppler; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000601:surgery*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D008944:Mitral Valve Insufficiency / Q000150:complications; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000601:surgery*
chemical_list: D000900:Anti-Bacterial Agents