title: [Dose and time dependency of "CT clearance"].
abstract: The contrast medium dose used in CT renal function analysis corresponds to about 1 ml/kg body weight at a measurement interval of 5 or 10 minutes. In the present study the dependence of "CT clearance" on dosage and time was examined in 12 healthy subjects. The amount of clearance was directly proportional to the employed contrast medium dose and to the length of the measurement interval. On account of the superior signal-to-noise ratio, the higher dose (1 ml/kg body weight) will continue to be preferred in future. The measurement interval can be limited to 10 minutes.
authors.affiliation: Institut für klinische Strahlenkunde am Klinikum Johannes Gutenberg-Universität Mainz.
authors.forename: H A
authors.initials: HA
authors.lastname: Kaltenborn
authors.forename: K J
authors.initials: KJ
authors.lastname: Klose
authors.forename: C
authors.initials: C
authors.lastname: Dexheimer
authors.lastname: von Steinijans
mesh_terms: D000328:Adult; D003287:Contrast Media / Q000008:administration & dosage / Q000493:pharmacokinetics*; D005260:Female; D006801:Humans; D007482:Iothalamate Meglumine / Q000008:administration & dosage / Q000493:pharmacokinetics*; D007668:Kidney / Q000000981:diagnostic imaging / Q000502:physiology; D007677:Kidney Function Tests / Q000379:methods*; D008297:Male; D012016:Reference Values; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; C001694:meglumine ioxithalamate; D007482:Iothalamate Meglumine
vernacular_title: Die Dosis- und Zeitabhängigkeit der "CT-Clearance".