title: A quasi-constant composition method for studying the formation of artificial caries-like lesions.
abstract: Caries-like lesions were formed in human tooth enamel in a quasi-constant composition titration system without the use of surface dissolution inhibitors or weak acids. The titration system maintained the composition of the demineralizing solution constant to within 6% on the average. Thus, the rate of lesion formation may be quantitatively assessed from the rate of titration. The system has sufficient sensitivity for measuring the rate of lesion formation in a small area, e.g., 15 mm2, of a single human enamel specimen.
authors.affiliation: American Dental Association Health Foundation, National Institute of Standards and Technology, Gaithersburg, Md.
authors.forename: L C
authors.initials: LC
authors.lastname: Chow
authors.forename: S
authors.initials: S
authors.lastname: Takagi
mesh_terms: D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003731:Dental Caries / Q000209:etiology*; D003743:Dental Enamel / Q000473:pathology; D003747:Dental Enamel Solubility / Q000187:drug effects; D004867:Equipment Design; D006801:Humans; D006851:Hydrochloric Acid / Q000008:administration & dosage; D006863:Hydrogen-Ion Concentration; D008852:Microradiography; D008859:Microscopy, Polarization; D008954:Models, Biological
chemical_list: D006851:Hydrochloric Acid