[Malignant cells in voided urine from elderly men contacted by mail].
Urine cytological examination among elderly men in an urban region will increase the number of current cases of cancer of the bladder in the first year in which this form of investigation is offered from 1.7 to 3.7 per 1,000 men examined. In order to achieve this result, an overdiagnosing occurs in the 1,045 participants as five men were offered cystoscopy without confirmation of malignancy during the follow-up period. Among seven men who defaulted for one reason or another, three had degrees of malignancy of II and III. The newly discovered cases of cancer of the bladder, only three in number, do not, however, represent any particular health benefit as regards degree of malignancy or tumour stage. The cytological validity for the entire group of participants revealed a nosographic sensitivity of 0.5, a predictive positive value of 0.14 and a nosographic specificity of 0.96 but, in the particular group with positive cytology, the predictive positive value was 0.54. The prevalence proportion was calculated to 7.3 per 1,000 men per annum.
Fischer
S
S
D000368:Aged; D003718:Denmark; D006801:Humans; D008297:Male; D008403:Mass Screening; D014505:Urban Population; D001749:Urinary Bladder Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000652:urine*
Maligne celler i ladt urinprøve fra aeldre maend postalt indbudt.