Comments on estimations of risks to translocation carriers.
Two projects for estimation of risks to carriers of reciprocal translocations based on data from more than 1,100 families are compared. The 2 projects differ considerably with regard to the amount of information utilized in the data, the statistical methods used--either standard computer programs or methods specially developed for the data--and the relevance and variety of the obtained results. The comparison shows the strength of utilizing tailor-made statistical methods for extracting relevant information from available data in human genetics instead of statistical standard methods from general computer programs.
Stene
J
J
Institute of Statistics, University of Copenhagen, Denmark.
D000013:Congenital Abnormalities / Q000235:genetics*; D004812:Epidemiologic Methods; D005260:Female; D005817:Genetic Counseling; D006579:Heterozygote; D006801:Humans; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012306:Risk; D014178:Translocation, Genetic