Pulmonary hemosiderosis in a child with cystic fibrosis.
Two episodes of acute iron deficiency anemia with blood-stained sputum and symptoms of severe acute pulmonary exacerbation were observed in a child with cystic fibrosis (CF). Hemosiderin laden macrophages (siderophages) were repeatedly found in sputum and gastric juice, suggesting the coexistence of pulmonary hemosiderosis (PH). The possibility that pulmonary immune-mediated mechanisms characteristic of CF may have played a role in the development of PH is considered.
Valletta
E A
EA
Cystic Fibrosis and Pediatric Pneumology Center, Ospedale Civile Maggiore, Verona, Italy.
Cipolli
M
M
Cazzola
G
G
Mastella
G
G
D003550:Cystic Fibrosis / Q000150:complications*; D003937:Diagnosis, Differential; D005260:Female; D006486:Hemosiderosis / Q000209:etiology*; D006801:Humans; D007223:Infant; D008171:Lung Diseases / Q000209:etiology*; D012307:Risk Factors