title: Morphological differentiation of the Müller cell: Golgi and electron microscopy study in the chick retina.
abstract: The sequence of morphological differentiation of Müller cells in the chick retina was investigated in relation to the differentiation of the retinal neurons using the Golgi method. From the beginning of differentiation, the Müller cell develops spurs and lateral processes. Some of these glial processes become transformed into accessory prolongations of the Müller cell. From the 17th or 18th day of incubation, the morphology of the Müller cells is similar to that of the adult retina. On the basis of their inner prolongation, two types of Müller cells were identified. The first type, with diffuse and abundant descending processes, is identical to that described classically. The second type is a cell characterized by sparse and scanty inner ramifications. This report also describes electron microscopic observations of Müller cells and their enwrapping relationship with the axons of the optic nerve fiber layer.
authors.affiliation: Instituto de Biologia del Desarrollo, Facultad de Medicina, Universidad de Sevilla, Spain.
authors.forename: F A
authors.initials: FA
authors.lastname: Prada
authors.forename: M M
authors.initials: MM
authors.lastname: Magalhaes
authors.forename: A
authors.initials: A
authors.lastname: Coimbra
authors.forename: J M
authors.initials: JM
authors.lastname: Genis-Galvez
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D002642:Chick Embryo; D002645:Chickens; D006056:Golgi Apparatus / Q000648:ultrastructure*; D008854:Microscopy, Electron; D012160:Retina / Q000166:cytology* / Q000648:ultrastructure