In situ hybridization localizes the human type II alpha 1 collagen gene (COL2A1) to 12q13.
We have, using in situ hybridization technique, localized the human type II alpha 1 collagen gene (COL2A1) to chromosome band 12q13. The gene had previously been assigned to either 12q13.1-13.2 or 12q14.3. Since the chromosome segment 12q13-15 has been shown to be rearranged in several benign and malignant human neoplasms, the exact band localization of COL2A1 within this region makes it a useful marker for the molecular analysis of these tumors.
Arheden
K
K
Mandahl
N
N
Heim
S
S
Mitelman
F
F
D002874:Chromosome Mapping; D002881:Chromosomes, Human, Pair 12; D003094:Collagen / Q000235:genetics*; D005796:Genes; D006801:Humans; D005810:Multigene Family; D009693:Nucleic Acid Hybridization
D003094:Collagen