title: A pink-pigmented, oxidative, nonmotile bacterium as a cause of opportunistic infections.
abstract: We describe two cases of bacteremia due to a pink-pigmented, oxidative, nonmotile, gram-negative, rod-shaped organism. One case occurred in a febrile neutropenic patient and another in a chronically debilitated patient with pancreatic abscess. The first patient was cured with gentamicin and ticarcillin, but the second patient died while receiving cefamandole therapy. The organisms described here are similar to Methylobacterium mesophilicum (Pseudomonas mesophilica) and the "unnamed taxon" organisms. A major difference from M mesophilicum is the lack of methanol utilization. Further distinctions between our isolates and M mesophilicum are the lack of flagella in our organisms, growth at 42 degrees C, growth on MacConkey's agar, lack of acetamide assimilation, and citrate utilization. The lack of flagella is the principle difference between our isolates and those in the unnamed taxon. Both of the isolates were resistant to the cephalosporins, but susceptible to the aminoglycosides, ticarcillin-clavulanic acid, sulfamethoxazole and trimethoprim, and imipenem. With the growing population of immunocompromised and chronically ill patients, these organisms may emerge as important pathogens.
authors.affiliation: Veterans Administration Medical Center, Infectious Disease Section, Pittsburgh, PA 15240.
authors.forename: J A
authors.initials: JA
authors.lastname: Korvick
authors.forename: J D
authors.initials: JD
authors.lastname: Rihs
authors.forename: G L
authors.initials: GL
authors.lastname: Gilardi
authors.forename: V L
authors.initials: VL
authors.lastname: Yu
mesh_terms: D000038:Abscess / Q000150:complications; D000328:Adult; D005260:Female; D006088:Gram-Negative Aerobic Bacteria / Q000302:isolation & purification* / Q000378:metabolism; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000209:etiology / Q000382:microbiology*; D010182:Pancreatic Diseases / Q000150:complications; D010860:Pigments, Biological; D014552:Urinary Tract Infections / Q000150:complications
chemical_list: D010860:Pigments, Biological