title: [Linkage studies in Emery-Dreifuss muscular dystrophy].
abstract: We report linkage studies between Emery-Dreifuss muscular dystrophy (EDMD) and polymorphic probes from the long arm of chromosome X in two pedigrees. The results don't show significant linkage but are consistent with previous localisation of EDMD in Xq28. Further studies will be necessary to apply molecular biology to genetic counselling and prenatal diagnosis of this disease.
authors.affiliation: Centre de génétique médicale et INSERM U.242, Hôpital d'Enfants de la Timone, Marseille.
authors.forename: V
authors.initials: V
authors.lastname: Paquis
authors.forename: N
authors.initials: N
authors.lastname: Philip
authors.forename: M A
authors.initials: MA
authors.lastname: Voelckel
authors.forename: J
authors.initials: J
authors.lastname: Pouget
authors.forename: B
authors.initials: B
authors.lastname: Lemieux
authors.forename: J F
authors.initials: JF
authors.lastname: Mattei
authors.forename: F
authors.initials: F
authors.lastname: Giraud
mesh_terms: D015342:DNA Probes; D008040:Genetic Linkage; D006801:Humans; D009136:Muscular Dystrophies / Q000235:genetics*; D010375:Pedigree; D014960:X Chromosome / Q000032:analysis*
chemical_list: D015342:DNA Probes
vernacular_title: Etudes de liaison dans la dystrophie musculaire d'Emery-Dreifuss.