Orbital myositis and giant cell myocarditis.
A 65-year-old woman developed progressive, bilateral ophthalmoplegia, with thickened extraocular muscles on CT. One month later, a cardiac arrhythmia led to her death. Pathologically, the extraocular and skeletal muscles showed diffuse mononuclear cell inflammation, while the heart contained granulomatous myositis. This patient's syndrome of idiopathic, orbital myositis and giant cell myocarditis may be a distinct nosologic entity.
Klein
B R
BR
Department of Ophthalmology, Tufts University School of Medicine, New England Medical Center, Boston, MA.
Hedges
T R
TR
Dayal
Y
Y
Adelman
L S
LS
D000368:Aged; D005260:Female; D006801:Humans; D009132:Muscles / Q000473:pathology; D009205:Myocarditis / Q000150:complications* / Q000473:pathology; D009220:Myositis / Q000150:complications* / Q000000981:diagnostic imaging; D009886:Ophthalmoplegia / Q000209:etiology; D009916:Orbital Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed