title: Effect of a mouthrinse containing calcium lactate on the formation and mineralization of dental plaque.
abstract: In this study, a mouthrinse containing calcium lactate was tested for its effect on the accumulation of dental plaque and on the concentrations of calcium and phosphorus therein. Human volunteers rinsed four times per day with a calcium lactate (165 mmol/l) solution for 1 week. Plaque samples, collected 16 h after the last rinse, were analyzed chemically. Calcium lactate rinses had no effect on the plaque score, but resulted in approximately twofold increases of calcium and phosphorus in plaque. The incorporation of monofluorophosphate (5 mmol/l) into the rinsing solution failed to show any significant influence on calcium, phosphorus, and fluoride levels in plaque. Increased mineral deposition in the plaque may provide an explanation for the reduced caries development earlier observed in rats fed a diet containing calcium lactate.
authors.affiliation: Department of Oral Health, University of Nijmegen, The Netherlands.
authors.forename: J S
authors.initials: JS
authors.lastname: van der Hoeven
authors.forename: M J
authors.initials: MJ
authors.lastname: Schaeken
authors.forename: T J
authors.initials: TJ
authors.lastname: Creugers
mesh_terms: D000328:Adult; D002118:Calcium / Q000032:analysis; D003773:Dental Plaque / Q000032:analysis / Q000209:etiology*; D004311:Double-Blind Method; D005260:Female; D005459:Fluorides / Q000008:administration & dosage / Q000032:analysis / Q000627:therapeutic use; D006801:Humans; D007773:Lactates / Q000008:administration & dosage / Q000627:therapeutic use*; D019344:Lactic Acid; D008297:Male; D009067:Mouthwashes; D010710:Phosphates / Q000008:administration & dosage / Q000627:therapeutic use; D010758:Phosphorus / Q000032:analysis; D013054:Spectrophotometry, Atomic
chemical_list: D007773:Lactates; D009067:Mouthwashes; D010710:Phosphates; C012980:fluorophosphate; D010758:Phosphorus; D019344:Lactic Acid; D005459:Fluorides; D002118:Calcium