title: [A case of hypertrophic obstructive cardiomyopathy with left atrial giant thrombus during anti-platelet therapy].
abstract: A case of a 77-year-old female with hypertrophic obstructive cardiomyopathy having the left atrial "giant" thrombus was reported; the diagnosis of the localization and size of the thrombus was made by employing echocardiography and contrast enhancement computed tomography as well. The clinical record indicated that the thrombus formation, which happened in the course of the antiplatelet therapy, was to be considered due to the complicated condition of the patient, i.e., the combination of atrial fibrillation, low cardiac output, enlargement of left atrium and left ventricular diastolic disfunction, which assumed to predispose the giant thrombus. Avoiding the surgical removal of the thrombus because of the poor conditions of the patient, urokinase treatment was attempted, but not successful, which might be derived from the nature of the thrombus already organized. In general, left atrial giant thrombus is very uncommon status; if any, it is occasionally complicated with mitral stenosis. The case reported deems to be very rare, enough worthy to be reported.
authors.forename: K
authors.initials: K
authors.lastname: Hata
authors.forename: N
authors.initials: N
authors.lastname: Kitada
authors.forename: T
authors.initials: T
authors.lastname: Gomyo
authors.forename: M
authors.initials: M
authors.lastname: Hamanaka
authors.forename: A
authors.initials: A
authors.lastname: Koganei
authors.forename: Z
authors.initials: Z
authors.lastname: Kan
authors.forename: S
authors.initials: S
authors.lastname: Kawaguchi
authors.forename: T
authors.initials: T
authors.lastname: Amemiya
mesh_terms: D000368:Aged; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications*; D003327:Coronary Disease / Q000209:etiology*; D003328:Coronary Thrombosis / Q000175:diagnosis / Q000209:etiology*; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006325:Heart Atria; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D013988:Ticlopidine / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
chemical_list: D010975:Platelet Aggregation Inhibitors; D013988:Ticlopidine