title: Transitory L-carnitine depletion in rat skeletal muscle by D-carnitine.
abstract: Weanling and adult rats were intraperitoneally injected with D-carnitine for 40 days. After 15 days of treatment a statistically significant depletion in the muscle levels of free and total L-carnitine was observed, but after 40 days this depletion became slight and statistically not significant. These findings suggest the presence of a compensatory mechanism acting on the inhibition of L-carnitine transport into skeletal muscle fibres.
authors.affiliation: Istituto di Neurologia, Universitá di Verona, Policlinico Borgo Roma.
authors.forename: O
authors.initials: O
authors.lastname: Arancio
authors.forename: G
authors.initials: G
authors.lastname: Bonadonna
authors.forename: M
authors.initials: M
authors.lastname: Calvani
authors.forename: P
authors.initials: P
authors.lastname: Giovene
authors.forename: G
authors.initials: G
authors.lastname: Tomelleri
authors.forename: D
authors.initials: D
authors.lastname: De Grandis
mesh_terms: D000375:Aging / Q000378:metabolism; D000818:Animals; D001835:Body Weight; D002331:Carnitine / Q000378:metabolism*; D008297:Male; D009132:Muscles / Q000033:anatomy & histology / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013237:Stereoisomerism
chemical_list: D002331:Carnitine