[The structure of eremomycin, a new antibiotic of the group of polycyclic glycopeptides].
Structure of the carbohydrate moiety of the eremomycin molecule was assessed. Two residues of eremosamine were detected in the antibiotic. One of them in the composition of 2-0-(L-eremosaminyl)-D-glucopyrazone dissaccharide was linked by the phenol group to monodechlorvancomycinic acid and the other formed the monosaccharide branch by the alcohol group of the same acid at the peptide C-end area. On the basis of the results of the present study and the data published earlier (structure of the aglycone and aminosugar) the structure of eremomycin was assigned.
Lomakina
N N
NN
Berdnikova
T F
TF
Tokareva
N L
NL
Abramova
E A
EA
Dokshina
N Iu
NIu
D000606:Amino Sugars / Q000032:analysis; D000900:Anti-Bacterial Agents; D002241:Carbohydrates / Q000032:analysis*; D002854:Chromatography, Paper / Q000379:methods; D006020:Glycopeptides / Q000032:analysis; D006027:Glycosides / Q000032:analysis; D006868:Hydrolysis; D008968:Molecular Conformation
D000606:Amino Sugars; D000900:Anti-Bacterial Agents; D002241:Carbohydrates; D006020:Glycopeptides; D006027:Glycosides; C053759:eremomycin
Struktura éremomitsina--novogo antibiotika gruppy politsiklicheskikh glikopeptidov.