title: Neurological and developmental findings in children with cataracts.
abstract: Ninety-seven children who were born between 1954 and 1986 and presented to the Visually Impaired Program of British Columbia's Children's Hospital, Vancouver, Canada, with a primary ophthalmologic diagnosis of cataracts, were assessed neurologically, ophthalmologically, audiologically, and developmentally. Causal factors included prenatal infection (35 cases), hereditary cataracts (22 cases), various syndromes and metabolic disorders (9 cases), trauma (1 case), and unknown (30 cases). Ninety children were diagnosed to have congenital cataracts while 7 acquired them. Findings indicated that prenatal infection continues to be a cause of infantile cataracts, despite rubella immunization; that prematurity is not, as has been stated in the past, a cause of infantile cataract; and that careful neurological, audiological, and developmental examination is vital in the assessment of likely causes of this condition.
authors.affiliation: Department of Paediatrics, University of British Columbia, Canada.
authors.forename: M G
authors.initials: MG
authors.lastname: Pike
authors.forename: J E
authors.initials: JE
authors.lastname: Jan
authors.forename: P K
authors.initials: PK
authors.lastname: Wong
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001955:British Columbia; D002386:Cataract / Q000151:congenital / Q000235:genetics / Q000378:metabolism; D002387:Cataract Extraction; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009460:Neurologic Examination; D009759:Nystagmus, Pathologic / Q000151:congenital; D011247:Pregnancy; D011248:Pregnancy Complications; D012189:Retrospective Studies; D012410:Rubella Syndrome, Congenital / Q000517:prevention & control