title: The occurrence of dopamine and related metabolites in the coronary and some other arteries.
abstract: 1. Bovine coronary and other arteries contain more dopamine (DA) [1400-520 ng g-1] than noradrenaline (NA) [120-500 ng g-1] with high DA/NA ratios (1.8-4.3). Arteries from other species, (pigs, rats, mice or guinea-pigs), contain far less DA (20-60 ng g-1) and have lower DA/NA ratios (0.01-0.06). 2. Bovine arteries also have 3,4-dihydroxyphenylacetic acid (80-290 ng g-1) but not homovanillic acid (less than 20 ng g-1). 3. It remains to be elucidated whether, in the bovine arterial wall, DA is a transmitter or it is associated with chromaffin-like cells.
authors.affiliation: Neuropsychiatric Research Unit, University of Saskatchewan, Saskatoon, Canada.
authors.forename: A V
authors.initials: AV
authors.lastname: Juorio
authors.forename: P J
authors.initials: PJ
authors.lastname: Chedrese
mesh_terms: D015102:3,4-Dihydroxyphenylacetic Acid / Q000378:metabolism; D000818:Animals; D001158:Arteries / Q000187:drug effects / Q000378:metabolism; D002417:Cattle; D003331:Coronary Vessels / Q000187:drug effects / Q000378:metabolism; D004298:Dopamine / Q000378:metabolism*; D005260:Female; D006168:Guinea Pigs; D006719:Homovanillic Acid / Q000378:metabolism; D007083:Iliac Artery / Q000187:drug effects; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013552:Swine
chemical_list: D015102:3,4-Dihydroxyphenylacetic Acid; D004298:Dopamine; D009638:Norepinephrine; D006719:Homovanillic Acid