The gene for human complement component C9 mapped to chromosome 5 by polymerase chain reaction.
The gene for human complement component C9 has been mapped to chromosome 5. This was achieved by using a novel application of the polymerase chain reaction to amplify specifically the human C9 gene on a background of rodent DNA in somatic cell hybrids. The assignment to chromosome 5 was confirmed by in situ hybridization to human metaphase chromosomes, giving a regional localization of 5p13.
Abbott
C
C
MRC Human Biochemical Genetics Unit, Galton Laboratory, University College London, United Kingdom.
West
L
L
Povey
S
S
Jeremiah
S
S
Murad
Z
Z
DiScipio
R
R
Fey
G
G
D000818:Animals; D002874:Chromosome Mapping; D002895:Chromosomes, Human, Pair 5; D003186:Complement C9 / Q000235:genetics*; D006224:Cricetinae; D003412:Cricetulus; D005784:Gene Amplification; D005796:Genes; D006801:Humans; D006822:Hybrid Cells; D051379:Mice; D051381:Rats
D003186:Complement C9