Effects of serine proteinase from Staphylococcus aureus V8 cells on Con A stimulation of human lymphocytes.
The combined effect of serum and Staphylococcus aureus serine proteinase on human lymphocyte Con A stimulation was assayed. Serum was found to protect the proteinase-treated lymphocytes. It is suggested that not only the immunogenicity of proteinase itself, but also proteinase modified serum and lymphocyte-derived components affect lymphoproliferative response.
Porwit-Bobr
Z
Z
Department of Microbiology and Immunology, Jan Zurzycki Institute of Molecular Biology, Jagiellonian University, Krakow, Czechoslovakia.
Ochalek
T
T
Prokesova
L
L
John
C
C
Baran
K
K
Potempa
J
J
D003208:Concanavalin A / Q000494:pharmacology*; D006801:Humans; D008213:Lymphocyte Activation / Q000187:drug effects*; D008214:Lymphocytes / Q000187:drug effects* / Q000276:immunology; D012697:Serine Endopeptidases / Q000276:immunology / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000201:enzymology* / Q000276:immunology
D003208:Concanavalin A; D012697:Serine Endopeptidases