Uncommon type of meningiomas with conspicuous plasmo-lymphocytic infiltration. An immunohistochemical and histochemical study.
Two cases of meningioma revealing conspicuous plasmo-lymphocytic tissue and hyalinized fibrous tissue components are reported. Histopathological examination of the plasmo-lymphocytic infiltration was performed. Both lesions showed polyclonality of plasma cells as revealed by positive reactions for IgG and paraimmunoglobulin kappa- and lambda-light chains, and amyloid infiltration into the fibrous stroma and blood vessel walls. The histochemical and immunohistochemical characteristics of the lesion in relation to its etiology are briefly discussed.
Ohmori
T
T
Second Department of Pathology, Ehime University School of Medicine, Japan.
Tabei
R
R
Fukui
K
K
Sadamoto
K
K
Sakaki
S
S
D000328:Adult; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications; D007150:Immunohistochemistry; D008214:Lymphocytes / Q000473:pathology*; D008297:Male; D008577:Meningeal Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D008579:Meningioma / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D008875:Middle Aged; D010950:Plasma Cells / Q000473:pathology*; D011859:Radiography