Anterior and posterior pituitary hormone release induced in sheep by cholecystokinin.
The effect of an intravenous bolus injection of cholecystokinin octapeptide (CCK-8; 0.85 micrograms/kg) on the release of cortisol, prolactin, vasopressin, and oxytocin was studied in sheep (n = 10). Concentrations of these hormones were measured in blood samples taken before (-10, 0 min) and after (5, 10, 20 min) administration of a saline vehicle or vehicle + CCK. Following CCK treatment, levels of cortisol were raised after 10 and 20 min, prolactin and vasopressin concentrations were increased after 5 min, and oxytocin secretion was unaffected.
Ebenezer
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IS
Agricultural and Food Research Council, Institute of Animal Physiology and Genetics Research, Cambridge Research Station, United Kingdom.
Thornton
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Parrott
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RF
D000818:Animals; D006854:Hydrocortisone / Q000097:blood; D010121:Oxytocin / Q000097:blood; D010908:Pituitary Hormones, Anterior / Q000097:blood / Q000378:metabolism*; D010909:Pituitary Hormones, Posterior / Q000097:blood / Q000378:metabolism*; D011388:Prolactin / Q000097:blood; D012016:Reference Values; D012756:Sheep; D012844:Sincalide / Q000494:pharmacology*; D014667:Vasopressins / Q000097:blood
D010908:Pituitary Hormones, Anterior; D010909:Pituitary Hormones, Posterior; D014667:Vasopressins; D010121:Oxytocin; D011388:Prolactin; D012844:Sincalide; D006854:Hydrocortisone