title: Synthesis and antibacterial activity of 5-methylcarbapenems.
abstract: Four possible racemic isomers of N-acetyl-5-methylthienamycin derivatives were synthesized and their antibacterial activities are discussed in relation to their physico-chemical properties. 5-Methylcarbapenems having various C-2 side chains were also prepared.
authors.affiliation: Shionogi Research Laboratories, Shionogi & Co., Ltd., Osaka, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Onoue
authors.forename: Y
authors.initials: Y
authors.lastname: Narukawa
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D055598:Chemical Phenomena; D002621:Chemistry; D007536:Isomerism; D015394:Molecular Structure; D013845:Thienamycins / Q000138:chemical synthesis / Q000494:pharmacology*
chemical_list: D013845:Thienamycins