[Emotional manifestations in the electrical stimulation of the hypothalamic nuclei in adult and old rats].
In experiments on adult (9-10 months) and old (24-26 months) white Wistar rats behavioural manifestations under electrical stimulation of the ventromedial hypothalamus nucleus and self-stimulation (SS) of the lateral hypothalamic region were studied. It has been found that with age electrical thresholds of negative emotional manifestations decrease with invariable SS thresholds. In old rats, in comparison with the adult ones, SS frequency is lower, maximum SS proceeds at lower currents, the range of currents capable to evoke an intensive SS is narrower, SS motivational component is less expressed. The obtained data testify that in old rats there exist neurophysiological preconditions for prevailing of negative emotional manifestations.
Rushkevich
Iu E
IuE
D000375:Aging / Q000502:physiology*; D000818:Animals; D004558:Electric Stimulation / Q000379:methods; D004567:Electrodes, Implanted; D004644:Emotions / Q000502:physiology*; D007026:Hypothalamic Area, Lateral / Q000502:physiology; D007031:Hypothalamus / Q000502:physiology*; D007033:Hypothalamus, Middle / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D012054:Reinforcement, Psychology; D012653:Self Stimulation / Q000502:physiology
Emotsional'nye proiavleniia pri élektricheskom razdrazhenii iader gipotalamusa u vzroslykh i starykh krys.