The influence of hypoxia and hyperoxia during metabolic acidosis and alkalosis on pulmonary haemodynamics.
In anaesthetised, mechanically ventilated Beagle dogs a moderate metabolic acidosis increased the pulmonary vascular resistance to a greater extent than moderate hypoxia. Alkalosis and hyperoxia did not alter the pulmonary vascular tone.
Oddoy
A
A
Research Institute of Lung Diseases and Tuberculosis, Berlin-Buch, GDR.
Danzmann
E
E
Herget
J
J
Sohn
S
S
Ritzau
E
E
Brandt
R
R
Böhnke
J
J
Merker
G
G
Noack
K
K
Harzendorf
E
E
D000138:Acidosis / Q000503:physiopathology*; D000471:Alkalosis / Q000503:physiopathology*; D000818:Animals; D001794:Blood Pressure; D002302:Cardiac Output; D004285:Dogs; D005260:Female; D006439:Hemodynamics; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D010100:Oxygen / Q000097:blood / Q000494:pharmacology*; D011652:Pulmonary Circulation; D012016:Reference Values; D014655:Vascular Resistance
D010100:Oxygen