[Cytopathogenic action of peripheral blood lymphocytes in patient with brucellosis].
The cytopathic action (CPA) of peripheral blood lymphocytes from 148 patients with different clinical forms of brucellosis has been studied in the culture of allogenic fibroblasts. The CPA of lymphocytes has been found to be observed more frequently and to a greater extent in chronic brucellosis than in acute and subacute brucellosis. No relationship between the CPA of lymphocytes and the severity of the disease or the allergic transformation of the body has been revealed. The CPA of lymphocytes has been found to coincide with the clinical manifestation and the duration of the course of brucellosis. The pathogenetic significance of the CPA of lymphocytes in brucellosis has been noted.
Mukovozova
L A
LA
Artemova
F M
FM
D000293:Adolescent; D000328:Adult; D002006:Brucellosis / Q000209:etiology / Q000276:immunology*; D002478:Cells, Cultured; D003601:Cytotoxicity Tests, Immunologic; D003602:Cytotoxicity, Immunologic; D005260:Female; D005347:Fibroblasts / Q000276:immunology; D006801:Humans; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged
Tsitopatogennoe deĭstvie limfotsitov perifericheskoĭ krovi u bol'nykh brutsellezom.