[Experimental studies on protalmine].
The effect of protein-hydrolysate preparation protalmine was studied on physical endurance and body weight of sexually mature rats. It was established that the preparation in a dose of 500 mg/kg of body weight increased static physical endurance and stability to electric stimuli. The effect was more manifested after oral administration of larger dose (1000 mg/kg of body weight). The body weight was not changed considerably in animals of the control group after one month treatment. It was established in other series of experiments performed on sexually mature rats that protalmine increased physical endurance, while Stark protein, used for comparison, did not affect this parameter considerably. Protalmine did not influence atrophy of seminal vesicles and ventral prostate in castrated young rats, e.g. it had no androgenic effect. After venous administration a slight decrease in arterial blood pressure and retardation of heart rate was manifested within the first 10-15 min. The results from these experiments showed that the protein-hydrolyzate preparation protalmine had marked stimulating action.
Taskov
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D000818:Animals; D001835:Body Weight / Q000187:drug effects*; D010807:Physical Endurance / Q000187:drug effects*; D011492:Protein Hydrolysates / Q000494:pharmacology* / Q000633:toxicity; D051381:Rats; D011919:Rats, Inbred Strains
D011492:Protein Hydrolysates
Eksperimentalin prouchvaniia na protalmin.