Enterotoxin production and serogroups of Campylobacter jejuni and Campylobacter coli from patients with diarrhea and from healthy laying hens.
Enterotoxin production, a possible virulence factor, was determined in Campylobacter jejuni and Campylobacter coli by two different techniques, the CHO cell test and the GM1 enzyme-linked immunosorbent assay. The frequency of enterotoxigenic Campylobacter strains was 32% in strains from both humans with acute enteritis and healthy laying hens, as measured by the CHO cell test. The CHO cell test was significantly more sensitive than the GM1 enzyme-linked immunosorbent assay in the detection of enterotoxigenic strains. Enterotoxin production was compared with the presence of heat-stable and heat-labile antigens. There was no significant correlation between enterotoxin production and serogroups for C. jejuni or C. coli. The difference in enterotoxigenicity between C. jejuni (34.1%) and C. coli (21.9%) was not significant.
Lindblom
G B
GB
Department of Clinical Bacteriology, University of Göteborg, Sweden.
Kaijser
B
B
Sjögren
E
E
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000818:Animals; D002167:Campylobacter / Q000145:classification / Q000378:metabolism* / Q000472:pathogenicity; D002169:Campylobacter Infections / Q000382:microbiology*; D002168:Campylobacter fetus / Q000145:classification / Q000378:metabolism* / Q000472:pathogenicity; D002353:Carrier State / Q000382:microbiology / Q000662:veterinary; D002460:Cell Line; D002645:Chickens; D003967:Diarrhea / Q000382:microbiology*; D004768:Enterotoxins / Q000096:biosynthesis*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005677:G(M1) Ganglioside; D006801:Humans; D011201:Poultry Diseases / Q000382:microbiology; D012703:Serotyping; D014774:Virulence
D004768:Enterotoxins; D005677:G(M1) Ganglioside