[The effect of levamisole on the functional activity and fatty acid composition of lymphocytes after the damage of cell membranes with tetrachloromethane].
After administration of tetrachlormethane into rats fatty acid composition of lymphocyte membrane phospholipids was altered, while functional activity of the cells was decreased. Levamisole exhibited protective effect, affecting apparently as an antioxidant.
Gubskiĭ
Iu I
IuI
Afonina
G B
GB
Briuzgina
T S
TS
Kravchenko
E Ia
EIa
Radlovskaia
Z T
ZT
D000818:Animals; D002251:Carbon Tetrachloride / Q000633:toxicity*; D002455:Cell Division / Q000187:drug effects; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D002784:Cholesterol / Q000378:metabolism; D005227:Fatty Acids / Q000378:metabolism*; D005260:Female; D007978:Levamisole / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects; D008214:Lymphocytes / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D010743:Phospholipids / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains
D005227:Fatty Acids; D010743:Phospholipids; D007978:Levamisole; D002784:Cholesterol; D002251:Carbon Tetrachloride
Vliianie levamizola na funktsional'nuiu aktivnost' i zhirnokislotnyĭ sostav limfotsitov pri povrezhdenii kletochnykh membran tetrakhlormetanom.