Oxidation of neplanocin A to the corresponding 3'-keto derivative by S-adenosylhomocysteine hydrolase.
Paisley
S D
SD
Department of Pharmaceutical Chemistry, University of Kansas, Lawrence 66045.
Wolfe
M S
MS
Borchardt
R T
RT
D000241:Adenosine / Q000031:analogs & derivatives / Q000378:metabolism; D043383:Adenosylhomocysteinase; D000818:Animals; D000998:Antiviral Agents / Q000378:metabolism*; D002417:Cattle; D055598:Chemical Phenomena; D002621:Chemistry; D002851:Chromatography, High Pressure Liquid; D006867:Hydrolases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D008099:Liver / Q000201:enzymology; D010084:Oxidation-Reduction
D000998:Antiviral Agents; C031096:neplanocin A; D006867:Hydrolases; D043383:Adenosylhomocysteinase; D000241:Adenosine