[Fibrotic fraction and myocardial cell diameter in latent cardiomyopathy].
100 left-ventricular endomyocardial biopsies of 32 patients were studied by means of morphometric and histological methods. No differences were found between patients with normal left ventricular end-diastolic pressure (LVEDP) and with increased LVEDP in the mean diameter of heart muscle cells, the distribution parameters coefficient of variation and kurtosis, and the volume density of the connective tissue. These patients did not show pathological findings of the other functional parameters and the coronary arteries. Statistically significant differences had been proved between patients with different histological diagnosis (post-myocarditic state, chronic-ischemic heart disease) with respect to the mean diameter of the myocytes (p less than 0.001) and the kurtosis of the distribution of myocytes' diameter (p less than 0.05).
Flegel
H G
HG
Institut für Pathologische Anatomie des Bereichs Medizin (Charité) der Humboldt-Universität zu Berlin.
Meyer
R
R
D001706:Biopsy; D001794:Blood Pressure; D002908:Chronic Disease; D003327:Coronary Disease / Q000473:pathology*; D006801:Humans; D009205:Myocarditis / Q000473:pathology*; D009206:Myocardium / Q000473:pathology*
Fibroseanteil und Herzmuskelzelldurchmesser bei latenter Cardiomyopathie.