Respiratory muscle weakness in Charcot-Marie-Tooth disease. A field study.
A field study on respiratory muscle function and basic pulmonary mechanics was conducted at an international convention of 200 individuals with Charcot-Marie-Tooth disease. Forty patients with respiratory symptoms were evaluated; 15 had significant respiratory muscle dysfunction and 25 were normal. The results suggest that proximal upper limb involvement in individuals with Charcot-Marie-Tooth disease is a simple but significant predictor of respiratory muscle dysfunction.
Nathanson
B N
BN
Department of Medicine, Wellesley Hospital, University of Toronto, Ontario, Canada.
Yu
D G
DG
Chan
C K
CK
D000293:Adolescent; D000328:Adult; D000368:Aged; D002607:Charcot-Marie-Tooth Disease / Q000503:physiopathology*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009134:Muscular Atrophy, Spinal / Q000503:physiopathology*; D012132:Respiratory Muscles / Q000503:physiopathology*