title: Self-administered drug compliance in Nepali leprosy patients.
abstract: The self administration of dapsone by Nepali leprosy patients receiving multidrug therapy was assessed by a colorimetric and a filter paper spot test. Overall 45 out of 337 (13.3%) patients were found to be non-compliant. The relation of non-compliance to sex, age, leprosy classification, therapy type and length of therapy was investigated. The spot test was compared with the colorimetric assay and found to have a relative sensitivity of 99.3% and specificity of 95.4%. Follow up of patients was successful in that two-thirds of non-compliant patients were compliant on their follow-up test.
authors.forename: P W
authors.initials: PW
authors.lastname: Roche
authors.forename: S
authors.initials: S
authors.lastname: Failbus
authors.forename: W
authors.initials: W
authors.lastname: Britton
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D003622:Dapsone / Q000008:administration & dosage* / Q000652:urine; D005260:Female; D006801:Humans; D007918:Leprosy / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D011237:Predictive Value of Tests; D012646:Self Administration
chemical_list: D003622:Dapsone