title: Computed tomography versus magnetic resonance imaging of the brain. A collaborative interinstitutional study.
abstract: A retrospective study (1983-1984) of magnetic resonance imaging (MRI) and computed tomography (CT) examinations in 471 patients with known pathology in the brain and craniocervical junction was conducted in order to determine the relative efficacy of MRI versus CT. All MRI examinations involved slice thickness greater than 10 mm, and only single-slice single-echo or multislice single-echo imaging techniques were available. These studies were evaluated independently by two neuroradiologists from a panel of six for anatomic abnormalities, lesion contrast, and radiologist's impression. Results, which excluded microadenomas of the pituitary and approximately 9% of studies in which consensus was not achieved by the readers, were as follows: (1) 14% of the studies were positive on MRI but normal on CT; (2) in 55% of the studies, MRI was better than CT; (3) MRI was equal or better than CT in 95% of the studies; and (4) CT was better than MRI in 5% (21/421) of the examinations. There were no patients in this series where CT was positive but MRI missed the abnormality.
authors.affiliation: Radiology Department, New York Hospital--Cornell Medical Center, NY 10031.
authors.forename: M D
authors.initials: MD
authors.lastname: Deck
authors.forename: C
authors.initials: C
authors.lastname: Henschke
authors.forename: B C
authors.initials: BC
authors.lastname: Lee
authors.forename: R D
authors.initials: RD
authors.lastname: Zimmerman
authors.forename: R A
authors.initials: RA
authors.lastname: Hyman
authors.forename: J
authors.initials: J
authors.lastname: Edwards
authors.forename: L A
authors.initials: LA
authors.lastname: Saint Louis
authors.forename: P T
authors.initials: PT
authors.lastname: Cahill
authors.forename: H
authors.initials: H
authors.lastname: Stein
authors.forename: J P
authors.initials: JP
authors.lastname: Whalen
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D001932:Brain Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging; D002574:Cervical Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology*; D002648:Child; D003560:Cysts / Q000175:diagnosis / Q000473:pathology; D005260:Female; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011856:Radiographic Image Enhancement; D012189:Retrospective Studies; D013122:Spinal Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed