title: Hydrofluoric acid dermal exposure.
abstract: A retrospective review of 237 consecutive cases of dermal exposure to dilute (6-11%) hydrofluoric acid (HF)- containing rust stain remover consumer products reported to the Rocky Mountain Poison and Drug Center during 1986 was done to evaluate the toxicity of these agents and the efficacy of topical treatment with calcium gluconate gel. In 148 cases (62%), failure to follow manufacturers' recommended safety procedures was the likely cause of exposure. 219 patients developed the following symptoms: dermal swelling, redness, or both (131, 55%); blistering (12, 5%); black discoloration under fingernails (12, 5%); or pain without reported dermal changes (64, 27%). Local complications were noted in 7 cases (3%) (infection, 4 cases; fingertip dermal necrosis, 3 cases). No systemic toxicity was noted. 116 patients (49%) received treatment with topical calcium gluconate gel; 53 were followed until complete resolution of symptoms. There appeared to be a relationship between earlier initial gel application and more rapid resolution of signs and symptoms. Some degree of dermal injury may be quite common following exposure to dilute (6-11%) HF-containing rust stain remover consumer products. Failure to follow manufacturers' recommended safety procedures may be responsible for many exposures. Treatment with topical calcium gluconate gel may be effective, and more rapid resolution of signs and symptoms may occur with earlier initiation of this therapy.
authors.affiliation: Rocky Mountain Poison and Drug Center, University of Colorado Health Sciences Center, Denver General Hospital 80204-4507.
authors.forename: M S
authors.initials: MS
authors.lastname: el Saadi
authors.forename: A H
authors.initials: AH
authors.lastname: Hall
authors.forename: P K
authors.initials: PK
authors.lastname: Hall
authors.forename: B S
authors.initials: BS
authors.lastname: Riggs
authors.forename: W L
authors.initials: WL
authors.lastname: Augenstein
authors.forename: B H
authors.initials: BH
authors.lastname: Rumack
mesh_terms: D002125:Calcium Gluconate / Q000627:therapeutic use; D003877:Dermatitis, Contact / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D006858:Hydrofluoric Acid / Q000633:toxicity*; D012189:Retrospective Studies; D012867:Skin / Q000187:drug effects
chemical_list: D006858:Hydrofluoric Acid; D002125:Calcium Gluconate