Distinction of influenza viruses of different host cell origin.
Influenza A viruses grown in different animal or human cells retain their antigenic make-up as tested by the usual immunological assays. With the aid of a Sambucus nigra (L.) extract containing its lectins the viruses can be distinguished after one single passage in a different cell type by a change in their hemagglutinating properties. Binding of such lectins to influenza viruses may be a means for a more subtle classification, relating to the host cell origin of the virus.
Sauter
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Department of Medicine, University Hospital, Zürich, Switzerland.
D000818:Animals; D002478:Cells, Cultured; D006389:Hemagglutinins, Viral / Q000032:analysis*; D006801:Humans; D009980:Influenza A virus / Q000145:classification*; D037102:Lectins; D037121:Plant Lectins; D054788:Ribosome Inactivating Proteins
D006389:Hemagglutinins, Viral; D037102:Lectins; D037121:Plant Lectins; C050600:Sambucus nigra lectins; D054788:Ribosome Inactivating Proteins