title: [Effect of oxytocin on fibrinolysis and the status of the kallikrein-kinin system].
abstract: The effect of the neuropeptide oxytocin, administered i. m., on the state of fibrinolysis and the kallikrein-kinin system was studied throughout an experiment on 88 Wistar albino nonpregnant female rats. Oxytocin was shown to cause fibrinolytic activation as a result of the elevated activity of the plasmin enzyme, plasminogen activators and the suppressed activity of antiplasmins. At the same time oxytocin stimulated the activity of the kallikrein-kinin system as was seen from the reduced level of serum kallikreinogen and the increased level of kallikrein.
authors.forename: V F
authors.initials: VF
authors.lastname: Kirichuk
authors.forename: M B
authors.initials: MB
authors.lastname: Burova
mesh_terms: D000818:Animals; D005260:Female; D005342:Fibrinolysis / Q000187:drug effects*; D007610:Kallikreins / Q000097:blood*; D007705:Kinins / Q000097:blood*; D010121:Oxytocin / Q000494:pharmacology*; D010960:Plasminogen Activators / Q000097:blood; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D007705:Kinins; D010121:Oxytocin; D007610:Kallikreins; D010960:Plasminogen Activators
vernacular_title: Vliianie oksitotsina na fibrinoliz i sostoinie kallikrein-kininovoĭ sistemy.