title: [An experimental model of DIC syndrome].
abstract: Disseminated intravascular coagulation syndrome (DIC-syndrome) is experimentally reproduced by introduction of 30% aqueous solution "Desoxon-3" (2800-300 mg/kg) into the organism of laboratory animals (rabbits). The preparation was perorally introduced once on an empty stomach for 1 min. Biochemical and pathomorphological studies testify to the development of the typical DIC-syndrome in rabbits. It is concluded that the model suggested makes it possible to thoroughly study genesis, course, consequences of the development and preventive measures of disseminated intravascular blood coagulation, a complex pathological process.
authors.forename: B M
authors.initials: BM
authors.lastname: Shchepotin
authors.forename: Ia M
authors.initials: IaM
authors.lastname: Ena
authors.forename: V A
authors.initials: VA
authors.lastname: Dibrova
authors.forename: E A
authors.initials: EA
authors.lastname: Shevchenko
authors.forename: G N
authors.initials: GN
authors.lastname: Vinogradova
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004211:Disseminated Intravascular Coagulation / Q000473:pathology*; D008833:Microcirculation / Q000473:pathology; D011817:Rabbits; D013927:Thrombosis / Q000473:pathology*; D014781:Viscera / Q000098:blood supply*
vernacular_title: Eksperimental'naoa model' DVS-sindroma.