title: Uranium in the tissues of an occupationally exposed individual.
abstract: Uranium concentrations were radiochemically determined in samples of lung, kidney, liver and bone collected at autopsy from an occupationally exposed individual. Levels of U in these tissues were clearly in excess of those expected from environmental exposure. Deposition followed the pattern: skeleton greater than liver greater than kidney, with ratios of 63:2.8:1. The data suggest there is an important long-term storage depot in the skeleton, but the fraction transferred to this compartment, as proposed by ICRP 30, may be too small. In vivo chest counts obtained over about a 10-y period prior to death indicated about a factor of 2 greater in total U content and 235U enrichment than deposition estimates made at autopsy for the lungs and associated lymph nodes.
authors.affiliation: Hanford Environmental Health Foundation, United States Uranium Registry, Richland, WA 99352.
authors.forename: R L
authors.initials: RL
authors.lastname: Kathren
authors.forename: J F
authors.initials: JF
authors.lastname: McInroy
authors.forename: R H
authors.initials: RH
authors.lastname: Moore
authors.forename: S E
authors.initials: SE
authors.lastname: Dietert
mesh_terms: D001842:Bone and Bones / Q000032:analysis; D002617:Chemical Industry; D004781:Environmental Exposure; D006283:Health Physics; D006801:Humans; D007668:Kidney / Q000032:analysis; D008099:Liver / Q000032:analysis; D008168:Lung / Q000032:analysis; D008297:Male; D008875:Middle Aged; D011829:Radiation Dosage; D014018:Tissue Distribution; D014501:Uranium / Q000032:analysis* / Q000652:urine
chemical_list: D014501:Uranium