3 beta-O-palmityl longispinogenin from Trichocereus chilensis.
From the aerial parts of Trichocereus chilensis a new triterpenetriol fatty acid ester was isolated. Its structure was shown to be 3 beta-O-palmityl longispinogenin (olean-12-ene-3 beta,16 beta,28-triol-3-palmitate) [1] by chemical and spectroscopic methods. Compound 1 is inactive in brine shrimp lethality and cytotoxicity bioassays.
Morales
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Department of Medicinal Chemistry and Pharmacognosy, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, Indiana 47907.
McLaughlin
J L
JL
D000107:Acetylation; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D001681:Biological Assay; D004353:Drug Evaluation, Preclinical; D006801:Humans; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D010168:Palmitates / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology; D010169:Palmitic Acids / Q000302:isolation & purification*; D008517:Phytotherapy; D010944:Plants / Q000032:analysis*; D014315:Triterpenes / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured / Q000187:drug effects
D000972:Antineoplastic Agents, Phytogenic; D010168:Palmitates; D010169:Palmitic Acids; D014315:Triterpenes; C060407:O-palmityllongispinogenin