title: Conformational analysis of antifolates: molecular structure and enzyme binding of the 4'-COOH trimethoprim derivative.
authors.affiliation: Molecular Biophysics Department, Medical Foundation of Buffalo, Inc., New York 14203.
authors.forename: V
authors.initials: V
authors.lastname: Cody
authors.forename: P A
authors.initials: PA
authors.lastname: Sutton
mesh_terms: D000818:Animals; D001665:Binding Sites; D002645:Chickens; D015195:Drug Design; D008099:Liver / Q000201:enzymology; D008958:Models, Molecular; D008968:Molecular Conformation; D011487:Protein Conformation; D013329:Structure-Activity Relationship; D013762:Tetrahydrofolate Dehydrogenase / Q000378:metabolism*; D014295:Trimethoprim / Q000031:analogs & derivatives* / Q000378:metabolism*
chemical_list: D014295:Trimethoprim; D013762:Tetrahydrofolate Dehydrogenase