title: [Kinetics of oxygen metabolism in pregnant women with high risk of developing late toxemia during intermittent normobaric hypoxia].
abstract: Oxygen metabolism kinetics (OMK) was investigated in 90 pregnant females with high risk for late gestoses and associated vascular disorders (essential hypertension, stage I, and neurocirculatory asthenia of hyper- and hypotonic type) exposed to preventive treatment with intermitting normobaric hypoxia (INH). The study revealed that initial disorders of tissue respiration were featured with compensatory stimulation of tissue oxygen consumption. In early signs of late gestosis the consumption intensity was found to be diminished. During INH treatment course there was an evidence of normalization in oxygen metabolism. The time-course of OMK values permitted to assess the level of systemic adaptation to hypoxia in pregnancy. INH technique was proved to be an efficient nonpharmacological method of late gestosis prevention.
authors.forename: A Ia
authors.initials: AIa
authors.lastname: Chizhov
authors.forename: I A
authors.initials: IA
authors.lastname: Evgen'eva
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Karash
mesh_terms: D005260:Female; D006801:Humans; D000860:Hypoxia / Q000378:metabolism*; D010100:Oxygen / Q000008:administration & dosage* / Q000493:pharmacokinetics; D010101:Oxygen Consumption; D011225:Pre-Eclampsia / Q000209:etiology / Q000517:prevention & control*; D011247:Pregnancy / Q000378:metabolism*; D011263:Pregnancy Trimester, Third; D012307:Risk Factors
chemical_list: D010100:Oxygen
vernacular_title: Kinetika kislorodnogo metabolizma u beremennykh gruppy vysokogo riska razvitiia pozdnego toksikoza pri ispol'zovanii preryvistoĭ normobaricheskoĭ gipoksii.