title: Brown tumor of bone: a potential source of false-positive thallium-201 localization.
abstract: Brown tumor of bone (osteitis fibrosa cystica) should be included in the differential diagnosis of lesions that cause false-positive thallium-201 localization in patients with primary hyperparathyroidism. We report a case of a brown tumor of the upper sternum mimicking a superior mediastinal parathyroid neoplasm in a patient with persistent hyperparathyroidism 9 years after a negative neck exploration (with subtotal thyroidectomy and thymectomy). A 201TI/99mTc pertechnetate subtraction scintigram demonstrated complete subtraction of this 201TI focus.
authors.affiliation: Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City 52242.
authors.forename: C J
authors.initials: CJ
authors.lastname: Yang
authors.forename: J E
authors.initials: JE
authors.lastname: Seabold
authors.forename: N J
authors.initials: NJ
authors.lastname: Gurll
mesh_terms: D001842:Bone and Bones / Q000000981:diagnostic imaging*; D002828:Choristoma / Q000000981:diagnostic imaging; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications; D008875:Middle Aged; D010002:Osteitis Fibrosa Cystica / Q000000981:diagnostic imaging* / Q000209:etiology; D010280:Parathyroid Glands; D011877:Radionuclide Imaging; D013249:Sternum / Q000000981:diagnostic imaging; D013794:Thallium Radioisotopes; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging
chemical_list: D013794:Thallium Radioisotopes