title: A clinico-bacteriological profile of leprosy in children.
abstract: Clinico-bacteriological profile of 106 leprosy patients below 15 years of age was studied. Majority of the patients were males and fell in the 10-15 years age group (p less than 0.01). Nearly 89% had not received any prior treatment because of financial constraints. Seventy per cent gave a positive history of contact with adult patients who were mainly of the lepromatous variety (p less than 0.01). Skin lesions were present in 103 cases, mainly on the exposed areas and their number was found to increase significantly with advancing age (p less than 0.01). These lesions were hypopigmented patches in 71% of the children and erythematous in the rest. Cutaneous sensations were affected in most of the patients while nerve thickening was observed in 45. Positivity of the skin smears increased significantly as the number of skin lesions per patient increased (p less than 0.05). With advancing age, the disease moved from the tuberculoid end of the spectrum towards the lepromatous end (p less than 0.01).
authors.forename: R
authors.initials: R
authors.lastname: Dayal
authors.forename: A K
authors.initials: AK
authors.lastname: Paliwal
authors.forename: R
authors.initials: R
authors.lastname: Prasad
authors.forename: P P
authors.initials: PP
authors.lastname: Mathur
authors.forename: V P
authors.initials: VP
authors.lastname: Bharadwaj
authors.forename: B K
authors.initials: BK
authors.lastname: Girdhar
authors.forename: D N
authors.initials: DN
authors.lastname: Pandey
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D007916:Lepromin / Q000276:immunology; D007918:Leprosy / Q000175:diagnosis* / Q000473:pathology / Q000635:transmission; D008297:Male; D012867:Skin / Q000473:pathology
chemical_list: D007916:Lepromin