title: Allergic reactions to the Australian paralysis tick, Ixodes holocyclus: diagnostic evaluation by skin test and radioimmunoassay.
abstract: Allergic reactions to Ixodes holocyclus are well recognized but poorly defined. Tick-bite reactions in 42 individuals in this study fell into six classes. Skin-prick tests and radioimmunoassay (RIA) indicated that all systemic hypersensitivity (class 3) and atypical reactions (class 4) were IgE-mediated. Some 73% of the large local reactions (class 2) and only 12.5% of the small local reactions (class 1) were associated with IgE specific for tick allergens. Subjects who reported heavy exposure to tick-bite were more likely to have positive RIA values (P less than 0.05). There was an association between the individual's atopic status and tick allergy (P greater than 0.05).
authors.affiliation: CSIRO, Division of Tropical Animal Production, Long Pocket Laboratories, Indooroopilly, Queensland, Australia.
authors.forename: M
authors.initials: M
authors.lastname: Gauci
authors.forename: R K
authors.initials: RK
authors.lastname: Loh
authors.forename: B F
authors.initials: BF
authors.lastname: Stone
authors.forename: Y H
authors.initials: YH
authors.lastname: Thong
mesh_terms: D000328:Adult; D000368:Aged; D001733:Bites and Stings / Q000145:classification / Q000276:immunology*; D002648:Child; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000145:classification / Q000175:diagnosis*; D007073:Immunoglobulin E / Q000097:blood; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D012882:Skin Tests; D013985:Tick Paralysis / Q000145:classification / Q000276:immunology*; D013986:Tick Toxicoses / Q000276:immunology*
chemical_list: D007073:Immunoglobulin E