[Bacteriological study of chronic paranasal sinusitis].
Analysis was done on the bacteria flora and the antibiotic sensitivity of 533 maxillary sinuses in 430 patients with chronic sinusitis treated at the Kaohsiung Medical College Hospital during the past 10 years. Among antral flora, Streptococcus sp. were the most common (212 strains, 38.4%), followed by Staphylococcus epidermidis (140 strains, 25.4%) and Staphylococcus aureus (33 strains, 5.9%). These three G(+) bacteria made up 70% (69.87%) of the total. The percentage of gram-negative and anaerobic bacteria was 20.8% and 8.7%, respectively. Of the total bacteria cultures, 17.8% showed no-growth. These results were similar to those reported in a similar study 10 years before. For the Streptococci and Staphylococci (70% of the total number), the most susceptible antibiotics in vitro were cephalosporin, followed in order by clindamycin, erythromycin, chloramphenicol, and cotrimoxazole. The effectiveness of ampicillin, gentamicin, minocycline appears to have been decreasing in the past 10 years. Tetracycline and penicillin effectiveness was worse. The susceptibility spectrum of the G(-) bacteria did not appear greatly changed from 10 years ago, for example, colistin and newly-synthesized aminoglycoside were rather sensitive. In addition a review was conducted of related papers of the past 70 years with a discussion of some controversial problems.
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Juan
D001419:Bacteria / Q000302:isolation & purification*; D002908:Chronic Disease; D004352:Drug Resistance, Microbial; D006801:Humans; D008826:Microbial Sensitivity Tests; D012852:Sinusitis / Q000382:microbiology*