[Contribution of immunohistochemistry to the diagnosis of cervicofacial cancers].
In spite of classical morphological studies, a good number of cervico-facial cancers remain classified as undifferentiated. Thanks to the use of intracellular antigens, immunohistochemistry (IHC) allows for a differentiation of tumoral growths. 33 patients were used in this study within the last three years. After studying the different markers used, the authors consider their specificity and their reactivity, than their respective usefulness in the three main diagnostic cancer of the face. In 22 patients, IHC alone allowed a diagnosis and a specific therapeutic orientation. Material, technical and human demands must be considered along with the efficacity to the technique.
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Darrouzet
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Stoll
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Benassayag
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Deminière
D000911:Antibodies, Monoclonal; D014408:Biomarkers, Tumor / Q000032:analysis; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D007382:Intermediate Filaments / Q000276:immunology; D008207:Lymphatic Metastasis
D000911:Antibodies, Monoclonal; D014408:Biomarkers, Tumor
Apport de l'immunohistochimie dans le diagnostic des cancers cervico-faciaux.