Priming with alcuronium and tubocurarine accelerates the onset of neuromuscular block.
The individual rate of onset of action of tubocurarine and alcuronium has been examined with and without a priming dose of the same agent or the other agent, by measurement of changes in the evoked compound electromyogram of the adductor pollicis muscle. Priming was associated with acceleration of the onset of neuromuscular block.
Pollard
B J
BJ
Department of Anaesthesia, Manchester Royal Infirmary.
D000328:Adult; D000443:Alcuronium / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D009469:Neuromuscular Junction / Q000187:drug effects*; D013997:Time Factors; D014117:Toxiferine / Q000031:analogs & derivatives*; D014403:Tubocurarine / Q000008:administration & dosage / Q000494:pharmacology*
D014117:Toxiferine; D000443:Alcuronium; D014403:Tubocurarine