Use of Old World monkeys for acquired immunodeficiency syndrome research.
Mangabeys, macaques, and baboons persistently infected with human immunodeficiency virus (HIV)-2 NIH-DZ demonstrated no signs of immunodeficiency disease after 6-11 months following seroconversion. Thus Old World monkeys provide an animal model to investigate the effects of passive immunization (anti-HIV-2 antibodies) on HIV infection in primates.
Nicol
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I
Laboratoire de Physiologie Cellulaire, Université Pierre et Marie Curie, Paris, France.
Messinger
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D
Dubouch
P
P
Bernard
J
J
Desportes
I
I
Jouffre
R
R
Snart
R
R
Nara
P
P
Gallo
R C
RC
Zagury
D
D
D000163:Acquired Immunodeficiency Syndrome / Q000382:microbiology* / Q000517:prevention & control; D000818:Animals; D015153:Blotting, Western; D002520:Cercopithecidae; D004195:Disease Models, Animal; D004797:Enzyme-Linked Immunosorbent Assay; D015483:HIV Antibodies / Q000032:analysis; D015488:HIV Antigens / Q000032:analysis; D015498:HIV-2 / Q000276:immunology / Q000302:isolation & purification* / Q000648:ultrastructure; D007116:Immunization, Passive; D008253:Macaca mulatta; D010215:Papio
D015483:HIV Antibodies; D015488:HIV Antigens