[The effect of acute and chronic hypoxia on ascorbic acid levels in various areas of the brain, liver, adrenal glands and in biological fluids in 18-day-old rats].
The influence of acute and chronic hypoxia on the ascorbic acid content in liver, adrenal, plasma, cerebrospinal fluid and brain in 18-day-old rats was studied. Due to acute hypoxia a significant decrease in ascorbic acid concentration in the adrenal occurred. Its levels in plasma and cerebrospinal fluid increased significantly compared with controls. Chronic hypoxia caused a significant ascorbic acid concentration increase in all samples studied with the exception of olfactory lobe and vermis cerebelli.
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D000208:Acute Disease; D000311:Adrenal Glands; D000367:Age Factors; D000818:Animals; D001205:Ascorbic Acid / Q000097:blood / Q000134:cerebrospinal fluid / Q000378:metabolism*; D001921:Brain / Q000378:metabolism; D002908:Chronic Disease; D000860:Hypoxia / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains
D001205:Ascorbic Acid
Vliv akutní a chronické hypoxie na obsah askorbové kyseliny v různých oblastech mozku, játrech, nadledvinĕ a v biologických tekutinách u 18denních potkanů.