[Morphometric analysis of aortic endothelium and serum lipoproteins in rats during readaptation after 15-day hypokinesia].
On hypokinesia day 15, the serum concentration of beta-lipoproteins increased and that of alpha-lipoproteins decreased, and the aortic endothelium was damaged. During the recovery period, the amount of pre-beta-lipoproteins was normal. After hypokinesia the concentration of alpha-lipoproteins increased and returned to normal by the 10th day while that of beta-lipoproteins remained lower for a long time. During the recovery period the number of endothelial cells showing karyopyknosis and karyolysis was increased. At later recovery-periods, the surface area of endothelial cells and their cytoplasm increased and the nucleus/plasma ratio decreased. However, lesions in the structure of the endothelial layer were less expressed than during hypokinesia. In the recovery period, the number of binuclear cells and the number of mitoses grew suggesting greater activity of regeneratory processes.
Gansburgskiĭ
A N
AN
Potapov
P P
PP
Altukhova
V V
VV
Degtiareva
M A
MA
D000222:Adaptation, Physiological; D000818:Animals; D001013:Aorta, Thoracic / Q000473:pathology* / Q000648:ultrastructure; D002452:Cell Count; D002467:Cell Nucleus / Q000648:ultrastructure; D004730:Endothelium, Vascular / Q000473:pathology* / Q000648:ultrastructure; D008075:Lipoproteins, HDL / Q000097:blood*; D008077:Lipoproteins, LDL / Q000097:blood*; D051381:Rats; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000473:pathology* / Q000503:physiopathology; D013997:Time Factors
D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL
Morfometricheskiĭ analiz éndoteliia aorty i lipoproteidy krovi u krys v period readaptatsii posle 15 sut gipokinezii.