A 10-year comparison of mitral valve replacement with Carpentier-Edwards and Hancock porcine bioprostheses.
Two hundred fifty-three patients who underwent isolated mitral valve replacement with a porcine bioprosthesis had long-term evaluation. One hundred forty-seven patients received a Carpentier-Edwards porcine bioprosthesis and 106, a Hancock valve. There were no significant differences in preoperative clinical characteristics between the two groups. Cumulative follow-up was 1,375 patient-years. At 10 years, 93% +/- 2.5% of the patients in the Carpentier-Edwards group and 85% +/- 7.8% of those in the Hancock group were free from valve-related death (not significant), and 95% +/- 2% and 91% +/- 3.8%, respectively, were free from thromboembolism (not significant). At 10 years, 65% +/- 7.2% of the patients in the Carpentier-Edwards group and 66% +/- 7.2% of those in the Hancock group were free from structural valve deterioration (not significant), and 64% +/- 6% and 59% +/- 7.3%, respectively, were free from reoperation (not significant). We conclude that the first generation of Carpentier-Edwards and Hancock prostheses produce comparable long-term results in the mitral position.
Department of Cardiovascular Surgery, Hôpital Broussais, Paris, France.
P
P
Perier
A
A
Deloche
S
S
Chauvaud
J C
JC
Chachques
J
J
Relland
J N
JN
Fabiani
Y
Y
Stephan
P
P
Blondeau
A
A
Carpentier
D000206:Actuarial Analysis; D000328:Adult; D000368:Aged; D001705:Bioprosthesis; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000401:mortality; D006801:Humans; D008875:Middle Aged; D008943:Mitral Valve; D011183:Postoperative Complications / Q000453:epidemiology; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012086:Reoperation; D013927:Thrombosis / Q000209:etiology; D013997:Time Factors