[Blood supply of skeletal muscles in reactive hyperemia].
In 18 anesthetized cats, 60-sec occlusion of the m. gastrocnemius artery entailed a decrease in the muscle blood supply by 15-20 ml of the blood volume in the vessels whereas the post-occlusion increase in the blood flow restored the blood volume with 45% excess. The intravascular accumulation of the blood exerting a moderating effect upon the venous return while preserving the increased arterial inflow, can be regarded as an automatic way of limiting the hemodynamic excitation due to the postocclusion shifts and involved in systemic circulation. Papaverin interacts with the blood volume restoration and leads to insufficient restoration in the postocclusion period. This suggests that the postocclusion excessive restoration of the blood volume in muscle, as observed in control animals, can be due to an active vasodilatation of the capacitance portion of the intraorgan vascular bed.
N Ia
NIa
Shustova
I G
IG
Dik
V P
VP
Nedoshivin
V A
VA
Levtov
D000818:Animals; D001158:Arteries / Q000187:drug effects / Q000503:physiopathology; D001810:Blood Volume / Q000187:drug effects; D002415:Cats; D006940:Hyperemia / Q000503:physiopathology*; D009132:Muscles / Q000098:blood supply* / Q000187:drug effects; D010208:Papaverine / Q000494:pharmacology
D010208:Papaverine
Krovenapolnenie skeletnykh myshts pri reaktivnoĭ giperemii.