Perfusion of uremic blood ultrafiltrate on uncoated charcoal.
A granular uncoated charcoal removes from uremic blood ultrafiltrates many chemical species that are not removed by dialysis. Charcoal treatment dramatically improves the general condition of the patients and normalizes their blood pressure. To obtain a rapid depuration, the initial treatment should be intensive (at least 16 daily treatments) and the effects prolonged over time by once-a-week charcoal treatment between two standard hemodialyses. Biogel P2 chromatography documents well all the events of a depurative treatment that cannot be monitored by hematochemical analyses.
Dipartimento di Scienze e Tecnologie Biomediche, Università de L'Aquila, Rome, Italy.
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Politi
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Cerulli
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D'Angelo
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Scandurra
D002606:Charcoal; D004591:Electrophoresis, Polyacrylamide Gel; D005069:Evaluation Studies as Topic; D006440:Hemofiltration / Q000379:methods*; D006801:Humans; D006435:Renal Dialysis; D014511:Uremia / Q000097:blood / Q000628:therapy*
D002606:Charcoal