Cervical adenocarcinoma in women with nasopharyngeal carcinoma (NPC).
Multiple primary cancers account for only 0.38% of all cases in the Singapore Cancer Registry. The close temporal association of nasopharyngeal carcinoma (NPC) in three Chinese women with uterine cervical adenocarcinoma was observed in our department within a 3-month period; one other case was extracted from the local literature. Although NPC is a common neoplasm in local Chinese women, uterine cervical adenocarcinomas comprise only 8% of cervical cancers locally. The close occurrence of these cancers does not seem to be related to the therapy used for cervical cancer and suggests that an association of the Epstein-Barr virus (EBV) with uterine cervical adenocarcinoma should be further investigated.
Department of Obstetrics and Gynecology, National University of Singapore.
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P
Singh
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A
Ilancheran
S S
SS
Ratnam
L T
LT
Kim
A P
AP
O'Reilly
D000230:Adenocarcinoma / Q000473:pathology*; D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000473:pathology*; D002681:China; D005260:Female; D006801:Humans; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D002583:Uterine Cervical Neoplasms / Q000473:pathology*