Preliminary report of decreased serum magnesium in postmenopausal osteoporosis.
Serum, red cell, urinary and bone Mg levels have been measured in 10 post-menopausal osteoporotics. Osteoporosis was confirmed by clinical fracture, histological analysis and dual-photon absorptiometry quantification. When compared to a healthy population matched for age and sex, serum Mg levels were statistically significantly (p less than 0.05) lower in osteoporotics (0.82 +/- 0.06 mmol/l) compared to normal subjects (0.87 +/- 0.04 mmol/l). No difference appeared for red cell, urinary or bone Mg determination. If these results are confirmed in a long-term study, serum Mg might be added to a batch of tests used to discriminate a subset of patients with an increased risk of developing postmenopausal osteoporosis.
Reginster
J Y
JY
Department of Rheumatology and Physical Medicine, University of Liège, Belgium.
Strause
L
L
Deroisy
R
R
Lecart
M P
MP
Saltman
P
P
Franchimont
P
P
D000368:Aged; D001842:Bone and Bones / Q000378:metabolism*; D005260:Female; D006801:Humans; D008274:Magnesium / Q000097:blood / Q000378:metabolism* / Q000652:urine; D008875:Middle Aged; D010024:Osteoporosis / Q000378:metabolism*
D008274:Magnesium