Changes with aging in the bone mineral content of the lumbar spine and femoral neck in healthy women in Hungary.
The bone mineral content (BMC) of the lumbar spine and femoral neck was studied in relation to aging in healthy Hungarian women by duel photon-absorptiometric method. The data were compared with North-American and West-European values. The Hungarian values are lower than these for reported from North-America or France, but similar to the BMC values for Sweden. The observed vertebral and femoral bone loss could be well represented by cubic equations. The acceleration of bone loss seems to begin around 40 years. The rate of bone loss was similar to the published values but the decrease in bone loss in the 6th and 7th decades was more suggestive. With regard to the fracture-threshold below which the risk for non-traumatic fractures of vertebrae increases, about 60% of Hungarian women at age 50-59 and about 84% at age 60-69 are considered to be at risk. It is concluded that geographical and habitual differences might be important factors in the development and change of BMC for different populations.
1st Department of Medicine, Institute of Gerontology, Budapest, Hungary.
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Lakatos
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Krasznai
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Vargha
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Gergely
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Holló
D000328:Adult; D000368:Aged; D000375:Aging / Q000378:metabolism*; D001842:Bone and Bones / Q000378:metabolism*; D005260:Female; D005272:Femur Neck / Q000378:metabolism*; D006801:Humans; D006814:Hungary; D008159:Lumbar Vertebrae / Q000378:metabolism*; D008593:Menopause; D008875:Middle Aged; D008903:Minerals / Q000378:metabolism*; D010024:Osteoporosis / Q000453:epidemiology / Q000378:metabolism; D011877:Radionuclide Imaging / Q000379:methods; D012016:Reference Values
D008903:Minerals