Osteoradionecrosis of the jaw bones at the University of Kentucky Medical Center.
There is disagreement over the management of teeth in irradiated head and neck cancer patients. Some oral surgeons support preirradiation extraction; others favor maintaining teeth. Before 1974, The University of Kentucky Department of Radiation Medicine found osteoradionecrosis (ORN) of the jaw in 10.9% of 220 irradiated cancer patients. After a program of oral care was instituted, the incidence declined to 2.7%. Of 109 patients who received radiotherapy between 1976 and 1985, only three (2.7%) developed ORN of the mandible. There was also a reduction in patients treated with interstitial therapy during this time. A review of the most recent experiences shows that, with present management methods at the University of Kentucky, ORN is not a significant problem. Of 30 patients treated in 1986, only one had ORN, and this was of the maxilla. Post-irradiation extractions were not identified as a significant risk for necrosis. Hyperbaric oxygen is used as a treatment for persistent ORN.
Patel
P
P
Raybould
T
T
Maruyama
Y
Y
D006258:Head and Neck Neoplasms / Q000532:radiotherapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D007571:Jaw Diseases / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D010025:Osteoradionecrosis / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D011832:Radiation Injuries / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects