Distribution of cholecystokinin receptors in the dorsal vagal complex and other selected nuclei in the human medulla.
Cholecystokinin receptors were localized in human brainstem by quantitative autoradiography, using [3H]cholecystokininoctapeptide. Receptor densities were highest in the caudal medial region of the nucleus of the solitary tract (NTS). High densities also were present in the dorsal motor nucleus of the vagus, the principle nucleus of the inferior olive, the ventral region of the NTS, and the area postrema.
Hyde
T M
TM
Clinical Brain Disorders Branch, NIMH, Neurosciences Center at St. Elizabeths, Washington, DC 20032.
Peroutka
S J
SJ
D000368:Aged; D001345:Autoradiography; D006801:Humans; D008526:Medulla Oblongata / Q000166:cytology / Q000378:metabolism*; D008875:Middle Aged; D011949:Receptors, Cholecystokinin / Q000378:metabolism*; D014630:Vagus Nerve / Q000166:cytology / Q000378:metabolism*
D011949:Receptors, Cholecystokinin