Pharmacokinetics and clinical use of parenteral phenytoin, phenobarbital, and paraldehyde.
Intravenous phenytoin, phenobarbital, and paraldehyde are effective and safe for the treatment of acute seizures such as status epilepticus. All of these drugs should be infused in a diluted solution and at a slow rate to minimize the occurrence of adverse effects.
Ramsay
R E
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Department of Neurology, University of Miami, Florida.
D006801:Humans; D010242:Paraldehyde / Q000008:administration & dosage* / Q000493:pharmacokinetics; D010634:Phenobarbital / Q000008:administration & dosage* / Q000493:pharmacokinetics; D010672:Phenytoin / Q000008:administration & dosage* / Q000493:pharmacokinetics; D013226:Status Epilepticus / Q000188:drug therapy*
D010672:Phenytoin; D010242:Paraldehyde; D010634:Phenobarbital