Reduced sodium chloride intake normalises blood pressure distribution.
The blood pressure distribution of 172 healthy normotensive subjects aged 3-77 years receiving diets containing different amounts of sodium are presented. On their usual intake of sodium (154 +/- 63 mmol Na+/day) and after two weeks on a high sodium intake (201 +/- 92 mmol Na+/day) supine systolic and supine diastolic blood pressure distribution were positively skewed to the right. After two weeks on a reduced sodium diet (77 +/- 37 mmol Na+/day) the blood pressure distribution was normal. An incremental effect of sodium on diastolic blood pressure occurred in 22% of the subjects. The fall in blood pressure on the reduced sodium diet in these 'sodium sensitive' subjects reduced the mean blood pressure level, which was associated with 'normalisation' of the blood pressure distribution.
Department of Medicine, University of Newcastle, Australia.
J B
JB
Myers
D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology; D001794:Blood Pressure; D002648:Child; D002675:Child, Preschool; D003971:Diastole; D004039:Diet, Sodium-Restricted; D004351:Drug Resistance; D004573:Electrolytes / Q000652:urine; D006801:Humans; D008875:Middle Aged
D004573:Electrolytes