A familial chromosomal translocation t(6q;7q) with habitual abortions.
A familial balanced translocation between the long arms of chromosomes 6 and 7 is described. The break points are localized to 6q27 and 7q23. No phenotypical abnormalities were found in any of the three carriers, but spontaneous abortions were frequent and might be associated with the translocation due to unbalanced segregation.
Zhang
S Z
SZ
Department of Medical Genetics, West China University of Medical Sciences, Chengdu.
Wu
X Y
XY
Ho
Q
Q
Zhao
L
L
D000026:Abortion, Habitual / Q000235:genetics*; D000328:Adult; D002896:Chromosomes, Human, Pair 6; D002897:Chromosomes, Human, Pair 7; D005260:Female; D006801:Humans; D007621:Karyotyping; D010375:Pedigree; D011247:Pregnancy; D014178:Translocation, Genetic