[Vaginal cancer: primary invasive squamous cell carcinoma in adults].
Retrospective study of 80 cases treated at the Institute Curie from 1969 to 1982. This cancer is rare; it is generally seen in old women, mostly arising in the upper third. The treatment is exclusive radiation therapy in almost all the cases, through four pelvic fields up to a dose of 45/50 Gy. A boost dose is added with a perineal field, or curietherapy. Immediate tolerance is rather good and late severe complications are rare (6%). The 5-year survival rate is 52%. The prognostic factors, according to the Cox model, are: the clinical T stage (5-year survival rate of 66% in T1-T2 stages, and 30% in T3-T4 stages), the patient's age (5-year survival rate of 65% for the patients less than 70 years of age, 40% for the older ones), complete tumor regression 3 months after the end of the treatment (5-year survival rate of 71% for those patients, and only 12 months of median survival for the others who are all dead at 36 months).
Service de radiothérapie, Centre hospitalier de Niort, France.
P
P
Gesta
J
J
Fenton
G
G
Mathieu
A
A
Flahault
B
B
Asselain
A
A
Labib
J C
JC
Rosenwald
D000328:Adult; D000367:Age Factors; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology* / Q000401:mortality / Q000532:radiotherapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D014625:Vaginal Neoplasms / Q000453:epidemiology* / Q000401:mortality / Q000532:radiotherapy
Cancer du vagin: épithélioma épidermoïde primitif invasif de l'adulte.