[15N] ammonium test for liver function diagnosis.
The functional state of the liver can be assessed by oral administration of 15N labelled ammonium chloride (tracer) and subsequent isotope analysis of [15N]urea and [15N]ammonia in urine. Clinical tests based on the ratio of the excess abundances of [15N]ammonia to [15N]urea excreted in urine 3 hours after oral administration of the tracer gave values for patients with liver diseases which differed significantly from these of healthy subjects.
Jung
K
K
Faust
H
H
Matkowitz
R
R
D000641:Ammonia / Q000652:urine*; D000643:Ammonium Chloride; D005260:Female; D006801:Humans; D008099:Liver / Q000502:physiology* / Q000503:physiopathology; D008107:Liver Diseases / Q000175:diagnosis*; D008111:Liver Function Tests / Q000379:methods*; D008297:Male; D009587:Nitrogen Isotopes; D012016:Reference Values; D014508:Urea / Q000652:urine*
D009587:Nitrogen Isotopes; D000643:Ammonium Chloride; D000641:Ammonia; D014508:Urea