Mycobacterium avium-Mycobacterium intracellulare infection limited to the skin and lymph nodes in patients with AIDS.
Three patients with AIDS who were taking 3'-azido-3'-deoxythymidine (AZT) developed cutaneous abscesses from which Mycobacterium avium-Mycobacterium intracellulare was isolated. Culture of multiple blood samples and bone marrow aspirate from all three patients revealed that the infection was not disseminated. This is a rare form of presentation for this infection in AIDS patients. We speculate that the antiviral drug AZT was responsible for the localization of disease.
Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas 75235-8859.
D J
DJ
Barbaro
V L
VL
Orcutt
B M
BM
Coldiron
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000188:drug therapy; D000328:Adult; D006801:Humans; D008198:Lymph Nodes / Q000382:microbiology*; D008206:Lymphatic Diseases / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D015269:Mycobacterium avium Complex / Q000302:isolation & purification; D015270:Mycobacterium avium-intracellulare Infection / Q000175:diagnosis / Q000209:etiology*; D012874:Skin Diseases, Infectious / Q000175:diagnosis / Q000209:etiology*; D015215:Zidovudine / Q000627:therapeutic use
D015215:Zidovudine