Seminoma in pubertal patient with androgen insensitivity syndrome.
The case of a 14-year-old girl with complete androgen insensitivity syndrome and metastatic seminoma is reported. She was treated by bilateral adnexectomy, removal of paraaortic lymph nodes, postoperative radiation, and estrogen replacement therapy. She represents the fourth case of gonadal malignancy to be reported in a teenage patient with androgen insensitivity syndrome.
Hurt
W G
WG
Department of Obstetrics and Gynecology, Medical College of Virginia, Virginia Commonwealth University, Richmond.
Bodurtha
J N
JN
McCall
J B
JB
Ali
M M
MM
D000293:Adolescent; D013734:Androgen-Insensitivity Syndrome / Q000150:complications*; D003131:Combined Modality Therapy; D012734:Disorders of Sex Development / Q000150:complications* / Q000235:genetics; D004407:Dysgerminoma / Q000150:complications* / Q000628:therapy; D005260:Female; D005833:Genital Neoplasms, Female / Q000150:complications* / Q000628:therapy; D006801:Humans; D007621:Karyotyping; D013577:Syndrome