[Analysis of factors influencing prognosis in patients with advanced ovarian cancer].
Sixty-eight patients with advanced ovarian cancer were evaluated to determine factors influencing prognosis. In the background between 49 patients who died within three years after treatment and 19 still living after more than 3 years, there is no significant difference in age. Performance Status (PS), clinical stage, pathological type, mode of operation, number of PAC chemotherapy, use of radiation therapy, the volume of ascites, the degree of peritonitis carcinomatosa or the preoperative serum CA125 level. On the other hand, factors affecting prognosis are the presence of retroperitoneal lymph node metastasis, liver metastasis, and a decrease in the decline rate of serum CA125. The factors which worsened prognosis in the patients who died were: (1) advanced stage of PS (2) the mode of surgery (non-curative surgery), (3) ascites more than 2,000ml, (4) severe peritonitis carcinomatosa, (5) liver metastasis, (6) retroperitoneal lymph node metastasis, (7) mucinous cystadenocarcinoma as to pathological type, (8) the low decline rate of serum CA125.
Department of Obstetrics and Gynecology, Hamamatsu University School of Medicine.
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Kobayashi
D000328:Adult; D000368:Aged; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis; D001202:Ascitic Fluid / Q000473:pathology; D003131:Combined Modality Therapy; D003536:Cystadenocarcinoma / Q000401:mortality; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000276:immunology / Q000401:mortality* / Q000473:pathology / Q000628:therapy; D010052:Ovariectomy; D011379:Prognosis
D015295:Antigens, Tumor-Associated, Carbohydrate