Corticofugal influences on the responses of bat inferior collicular neurons to sound stimulation.
Corticofugal influences on the responses of inferior collicular neurons (IC) to acoustic stimulation were studied by electrical stimulation of the auditory cortex. Among 471 IC neurons isolated, about 26% were affected by cortical stimulation. Responses of 103 (22%) IC neurons were inhibited and 17 (3.6%) were facilitated. The degree of inhibition was dependent upon the amplitude of both auditory and electrical stimuli. Corticofugal inhibition of the response of an IC neuron was likely due to an increase in the neuron's minimum threshold. Inhibitory latency varied with the interstimulus interval. The shortest inhibitory latency of most IC neurons was between 1 and 2 ms. The localization of the point of cortical stimulation was crucial in determining the responses of IC neurons. It is assumed that corticofugal influences on IC neurons are a part of regulatory mechanism in the centrifugal pathway for frequency analysis and acoustic orientation.
Department of Biology, East China Normal University, Shanghai, P.R.C.
X D
XD
Sun
P H
PH
Jen
D X
DX
Sun
S F
SF
Zhang
D000161:Acoustic Stimulation; D000200:Action Potentials; D000818:Animals; D001303:Auditory Cortex / Q000502:physiology*; D001306:Auditory Pathways / Q000502:physiology; D002685:Chiroptera / Q000502:physiology*; D004558:Electric Stimulation; D005072:Evoked Potentials, Auditory; D007245:Inferior Colliculi / Q000502:physiology*; D009433:Neural Inhibition; D011930:Reaction Time / Q000502:physiology