Primidone/phenobarbital-induced periodic alternating nystagmus.
A 37-year-old man with a history of seizures developed periodic alternating nystagmus (PAN) along with other signs of primidone/phenobarbital toxicity. The PAN gradually diminished in cycle length and intensity, finally resolving with gradual discontinuation of the drugs.
Schwankhaus
J D
JD
Neurology Service, Veterans Administration Medical Center, Washington, DC.
Kattah
J C
JC
Lux
W E
WE
Masucci
E F
EF
Kurtzke
J F
JF
D000328:Adult; D004584:Electronystagmography; D005133:Eye Movements; D006801:Humans; D008297:Male; D009759:Nystagmus, Pathologic / Q000139:chemically induced*; D010507:Periodicity; D010634:Phenobarbital / Q000009:adverse effects*; D011324:Primidone / Q000009:adverse effects*; D014792:Visual Acuity
D011324:Primidone; D010634:Phenobarbital