Syntheses and antitumor activities of 7-O-(3-amino-2,3,6-trideoxy-2-fluoro-alpha-L-talopyranosyl)daunomvcinone and -adriamycinone.
Institute of Bioorganic Chemistry, Kanagawa, Japan.
Y
Y
Takagi
H
H
Park
T
T
Tsuchiya
S
S
Umezawa
T
T
Takeuchi
K
K
Komuro
C
C
Nosaka
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D003630:Daunorubicin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology / Q000627:therapeutic use; D004317:Doxorubicin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology / Q000627:therapeutic use; D007939:Leukemia L1210 / Q000188:drug therapy; D051379:Mice; D014407:Tumor Cells, Cultured / Q000187:drug effects
C060653:7(O)-(3-amino-2,3,6-trideoxy-2-fluorotalopyranosyl)adriamycinone; C060652:7-O-(3-amino-2,3,6-trideoxy-2-fluorotalopyranosyl)daunomycinone; D004317:Doxorubicin; D003630:Daunorubicin