Brain abscess in cyanotic congenital heart disease.
Twenty-eight patients of cyanotic congenital heart disease (CHD) complicated with brain abscess were reviewed. There were 22 males and 6 females with a mean age of 9.1 +/- 5.5 years. Tetralogy of Fallot was the commonest cyanotic CHD observed. Transposition of great arteries (PS), tricuspid atresia with VSD, PS and double outlet right ventricle with VSD comprised 25% of the cardiac lesions. Febrile illness was the commonest mode of presentation (42.86%). Frontal lobe was the commonest site of abscess localization (37.5%) followed by parietal lobe (32.5%). Multiple abscess were seen in 32.14% and in 35.7% the pus was sterile on culture. Twelve patients died (mortality -42.8%), and autopsy reports were available in 6. Infective endocarditis was suspected in 7 on clinical grounds, while at autopsy, out of 6 only 2 had evidence of right-sided endocarditis. There was no correlation of mortality with age, sex, type of micro-organism, site of abscess localization and the nature of heart disease. Multiple abscesses, features of raised intracranial tension and associated meningitis/ventriculitis predicted a grim outcome.
Chakraborty
R N
RN
Bidwai
P S
PS
Kak
V K
VK
Banarjee
A K
AK
Khattri
H N
HN
Sapru
R P
RP
Walia
B N
BN
Kumar
L
L
Suri
S
S
Wahi
P L
PL
D001922:Brain Abscess / Q000150:complications* / Q000175:diagnosis; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D013771:Tetralogy of Fallot / Q000150:complications*