Cardiovascular effects of butorphanol administration in isoflurane-O2 anesthetized healthy dogs.
Cardiovascular consequences of butorphanol tartrate (0.2 mg/kg of body weight, IV) administration during isoflurane (1.7% end-tidal concentration) anesthesia were determined in mechanically ventilated healthy dogs. Butorphanol administration caused significant (P less than or equal to 0.05) reductions in mean, systolic, and diastolic arterial blood pressures; cardiac output; and rate-pressure product.
Department of Veterinary Large Animal Medicine, Texas A&M University, College Station 77843.
C L
CL
Tyner
S A
SA
Greene
S M
SM
Hartsfield
D000136:Acid-Base Equilibrium; D000758:Anesthesia / Q000662:veterinary; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D001831:Body Temperature / Q000187:drug effects; D002077:Butorphanol / Q000008:administration & dosage / Q000494:pharmacology*; D002302:Cardiac Output / Q000187:drug effects*; D004285:Dogs / Q000502:physiology*; D005260:Female; D007530:Isoflurane; D008297:Male; D009019:Morphinans / Q000494:pharmacology*
D009019:Morphinans; D007530:Isoflurane; D002077:Butorphanol