Statistical methods for measuring interactions between protectors and sensitizers for freeze-thaw survival data.
A statistical model is developed to generate the survival probabilities of cells subjected to freeze-thaw treatments using various sensitizing and/or protective agents. The purpose is to determine whether different freeze-thaw protective agents act independently or whether there is an interaction between the agents. The model permits a statistical analysis of the data to yield an objective quantitative assessment of the size and nature of the interaction.
Department of Statistics and Actuarial Science, University of Waterloo, Ontario, Canada.
S R
SR
Chamberlin
J
J
Kruuv
D A
DA
Sprott
D002470:Cell Survival; D003451:Cryoprotective Agents; D005615:Freezing; D015233:Models, Statistical; D012984:Software; D014021:Tissue Preservation
D003451:Cryoprotective Agents