[Serum immunoglobulins and various components of complement in patients with insulin-dependent diabetes mellitus].
Serum concentrations of immunoglobulin (Ig) A, M, G and complement components C3, C4, Bf were investigated in 50 patients with insulin--dependent, non--insulin dependent diabetes of 60 patient and control healthy subjects. The mean level of IgA was lower and IgM and IgG higher in both types of diabetic patients. But the low level of IgG was observed in 11% patients with insulin dependent diabetes. It was not significant difference in concentrations of complement components proteins in both diabetic groups and control subjects. Insulin dependent diabetic patients with microangiopathic complications had lower level of serum C4, but this difference was not statistically significant.
Pietruska
Z
Z
Kinalska
I
I
Jabłońska
E
E
Czaczkowska
T
T
D000293:Adolescent; D000328:Adult; D003176:Complement C3 / Q000032:analysis*; D003181:Complement C4 / Q000032:analysis*; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology*; D004406:Dysgammaglobulinemia / Q000209:etiology; D006801:Humans; D006942:Hypergammaglobulinemia / Q000209:etiology; D017098:IgA Deficiency; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D008875:Middle Aged
D003176:Complement C3; D003181:Complement C4; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins
Zachowanie sie immunoglobulin i niektórych składników dopełniacza w surowicy chorych z cukrzyca insulinozalezna.