Developmental patterns of peroxisomal enzymes in amphibian liver during spontaneous and triiodothyronine-induced metamorphosis.
1. Liver catalase, D-amino acid oxidase, urate oxidase of Alytes obstetricans and Xenopus laevis (anuran amphibians) and fatty acyl-CoA oxidase of Alytes were present at all post-embryonic stages. 2. Catalase and D-amino acid oxidase activities increased during spontaneous metamorphosis of the two species. 3. During triiodothyronine-induced metamorphosis of Alytes larvae, catalase and D-amino acid oxidase activities increased after a latent period. 4. Our results suggest that expression of some hepatic peroxisomal enzymes is modulated by thyroid hormones.
Laboratoire de Biologie Cellulaire du Développement, Faculté des Sciences, Université de Nancy I, France.
E
E
Ciolek
J
J
Vamecq
F
F
Van Hoof
M
M
Dauça
A
A
Bautz
D000818:Animals; D001001:Anura / Q000254:growth & development* / Q000378:metabolism; D002374:Catalase / Q000378:metabolism; D007814:Larva / Q000201:enzymology; D008099:Liver / Q000201:enzymology / Q000648:ultrastructure*; D008675:Metamorphosis, Biological / Q000187:drug effects*; D008830:Microbodies / Q000201:enzymology*; D011394:Proline Oxidase / Q000378:metabolism; D014284:Triiodothyronine / Q000494:pharmacology*; D014503:Urate Oxidase / Q000378:metabolism; D014982:Xenopus laevis / Q000254:growth & development* / Q000378:metabolism
D014284:Triiodothyronine; D002374:Catalase; D011394:Proline Oxidase; D014503:Urate Oxidase