Collection of bronchoalveolar lavage fluid in cats, using an endotracheal tube.
Bronchoalveolar lavage fluid was collected from 12 anesthetized cats by use of an endotracheal tube and syringe adapter. The safety of the technique was evaluated by monitoring mucous membrane color, capillary refill time, pulse rate, respiratory rate, ECG, and arterial blood gas tensions and by necropsy findings. Group A consisted of 3 cats that were administered (by lavage) 4 aliquots of 20 ml of saline solution during anesthesia for placement of femoral artery catheters. Group B consisted of 4 cats that were administered a smaller total volume of saline solution (3 aliquots of 5 ml/kg of body weight) during a separate anesthetic period, other than the one for placement of catheters. Group C consisted of 5 cats administered 3 aliquots (5 ml/kg) of saline solution during a separate anesthetic period and administered supplemental oxygen for 5 to 10 minutes before and for 20 minutes after the lavage procedure. Group-A cats had a prolonged recovery period that was attributed to the lengthy anesthetic period required for placement of femoral catheters. The effect was eliminated in the cats of the other groups in which the lavage procedure itself accounted for only 5 to 10 minutes of anesthetic time. Evaluation of mucous membrane color, capillary refill time, ECG, pulse, and respiratory rate revealed no persistent abnormalities. Transient increase in pulse and respiratory rate was seen in some cats. Blood gas analysis revealed noticeable decrease in arterial oxygen pressures (Pao2) after the lavage procedure. In group-C cats, oxygen supplementation allowed the maintenance of normal or above normal Pao2.(ABSTRACT TRUNCATED AT 250 WORDS)
Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907.
E C
EC
Hawkins
D B
DB
DeNicola
D000818:Animals; D001784:Blood Gas Analysis / Q000662:veterinary; D001992:Bronchoalveolar Lavage Fluid; D002371:Cat Diseases / Q000175:diagnosis*; D002415:Cats; D007442:Intubation, Intratracheal / Q000662:veterinary*; D008171:Lung Diseases / Q000175:diagnosis / Q000662:veterinary; D008264:Macrophages; D008297:Male; D011897:Random Allocation; D012965:Sodium Chloride / Q000008:administration & dosage; D013048:Specimen Handling / Q000662:veterinary*; D013997:Time Factors
D012965:Sodium Chloride