The effects of butyrate and glucagon on the proliferation of ruminal epithelial cells in culture.
When the rate of ruminal epithelial cell proliferation was measured on the basis of 3H-thymidine incorporation into the cellular DNA, butyrate dose-dependently reduced 3H-thymidine incorporation. In contrast, glucagon at 10 and 100 pg/ml had a slight stimulatory effect on the incorporation, but only in the absence of butyrate.
Department of Physiology, University of Veterinary Sciences, Budapest, Hungary.
S
S
Neogrády
P
P
Gálfi
F
F
Kutas
T
T
Sakata
D000818:Animals; D002087:Butyrates / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D004847:Epithelial Cells; D005934:Glucagon / Q000494:pharmacology*; D012417:Rumen / Q000166:cytology*
D002087:Butyrates; D005934:Glucagon