Pre-operative albendazole therapy for recurrent hydatid disease.
Two patients with recurrent hydatid disease had a 1-month course of albendazole before surgery. In one case with a thick-walled host capsule, the scolicidal effect was incomplete, but, in the second case, in which thin-walled cysts were present, albendazole entered the cyst and was completely effective as a scolicidal agent. For thick-walled cysts, it may be necessary to use albendazole for more than 1 month pre-operatively in order to achieve a scolicidal effect.
Brough
W
W
Department of Surgery, University of Melbourne, Parkville, Victoria.
Hennessy
O
O
Rickard
M D
MD
Lightowlers
M W
MW
Kune
G A
GA
D000005:Abdomen; D000328:Adult; D015766:Albendazole; D001562:Benzimidazoles / Q000627:therapeutic use*; D004443:Echinococcosis / Q000188:drug therapy* / Q000601:surgery; D004444:Echinococcosis, Hepatic / Q000188:drug therapy* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011292:Premedication; D012008:Recurrence
D001562:Benzimidazoles; D015766:Albendazole