Dose-response studies on the spermatogonial stem cells of the rhesus monkey (Macaca mulatta) after X irradiation.
Studies of the dose response of the spermatogonial stem cells in the rhesus monkey were performed at intervals of 130 and 160 days after graded doses of X irradiation. The D0 of the spermatogonial stem cells was established using the total numbers of the type A spermatogonia that were present at 130 and 160 days after irradiation and was found to be 1.07 Gy; the 95% confidence interval was 0.90-1.34 Gy.
Department of Cell Biology, State University of Utrecht, Medical School, The Netherlands.
M M
MM
van Alphen
H J
HJ
van de Kant
J A
JA
Davids
C J
CJ
Warmer
A L
AL
Bootsma
D G
DG
de Rooij
D000818:Animals; D004307:Dose-Response Relationship, Radiation; D008253:Macaca mulatta; D008297:Male; D011836:Radiation Tolerance; D013093:Spermatogonia / Q000528:radiation effects*; D013094:Spermatozoa / Q000528:radiation effects*; D013234:Stem Cells / Q000528:radiation effects*