Adrenergic neurons in the nucleus tractus solitarius receive GABAergic synapses. Demonstration by dual immunocytochemistry in the rat.
By means of a dual immunocytochemical labeling for phenylethanolamine-N-methyltransferase and glutamate decarboxylase, synaptic associations between adrenaline-synthesizing neurons and GABAergic terminals are demonstrated in the medial nucleus tractus solitarius of the rat. These relationships could constitute an anatomical substrate for the presumed role of GABA in modulation of baroreceptor reflexes at this level.
Equipe de Neuromorphologie Fonctionnelle, Laboratoire de Neurobiologie, C.N.R.S., Marseille, France.
P
P
Kachidian
L
L
Denoroy
O
O
Bosler
D000320:Adrenergic Fibers / Q000378:metabolism* / Q000502:physiology; D000818:Animals; D005968:Glutamate Decarboxylase / Q000378:metabolism; D007150:Immunohistochemistry; D008297:Male; D008526:Medulla Oblongata / Q000166:cytology* / Q000378:metabolism; D008854:Microscopy, Electron; D009411:Nerve Endings / Q000378:metabolism* / Q000648:ultrastructure; D010625:Phenylethanolamine N-Methyltransferase / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D005680:gamma-Aminobutyric Acid; D010625:Phenylethanolamine N-Methyltransferase; D005968:Glutamate Decarboxylase