pH regulation of calcium efflux by turtle liver mitochondria.
1. Turtle liver mitochondria are capable of taking up calcium in a pattern similar to that described from rat liver mitochondria. 2. Turtle liver mitochondria also possess a system for calcium efflux which is extremely sensitive to changes in extramitochondrial pH. A decrease in extramitochondrial pH by addition of HCl or by gassing with CO2 caused a rapid release of calcium. 3. The profound changes in pH and pCO2 during deep diving likely affects Ca efflux from mitochondria in the turtle liver.
Section of Nephrology, University of Illinois College of Medicine, Chicago 60612.
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Arruda
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Dytko
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D006706:Homeostasis; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D014426:Turtles / Q000378:metabolism*
D002118:Calcium