[Magnetic resonance tomography of the breast. The results of 253 examinations].
Requirements for diagnostic magnetic resonance imaging (MRI) of breast disease were defined on the basis of 253 examinations over 4 1/2 years. The results were compared with those of mammography in 207, with histological findings in 145 cases. Examinations after injection of 0.1 mmol/kg Gd-DTPA (gadolinium diethylene-triamino-penta-acetate) and measurement of the same sections at short intervals proved to be the most informative MRI technique for the differentiation of benign and malignant changes. Carcinomas had a rapid initial rise in signal of more than 90% over the pre-injection level within one minute of contrast-medium administration. In 163 of 207 cases MRI provided information additional to mammography (confirmation or exclusion of a carcinoma; exact localization of a malignant process; differentiation between carcinoma and scar tissue; diagnosis of a tumour close to the thoracic cavity; changes near a prosthesis). Analysing only the examinations done with contrast-medium (144), there was a 99% sensitivity. There have been no false-negatives so far. Despite the high cost and time required, MRI of the breast is indicated when mammography, ultrasound and clinical features provide unclear and (or) discrepant findings.
Kaiser
W A
WA
Radiologisches Zentrum, Abteilung Diagnostik, Klinikum Nürnberg.
D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000175:diagnosis; D003287:Contrast Media; D005069:Evaluation Studies as Topic; D005188:False Negative Reactions; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008327:Mammography; D009942:Organometallic Compounds; D004369:Pentetic Acid; D013997:Time Factors
D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA
Magnetresonanztomographie der Mamma. Erfahrungen nach 253 Untersuchungen.