Effect of 36-hour starvation on in vivo amino acid and glucose uptake by rat brown adipose tissue.
The effect of 36-hour starvation on the net uptake/release of amino acids and glucose by interscapular brown adipose tissue (IBAT) of the rat has been studied by means of the determination of the arterio-venous differences in their blood concentrations. Starvation induced a net release of non-essential amino acids by the tissue, mainly alanine, glutamine, glycine and citrulline. In food deprived animals there was not a net glucose uptake by the IBAT. The results obtained in this study are in accordance with a typical peripheral tissue metabolic pattern of IBAT under food deprivation situations.
Department de Bioquímica i Fisiologia, Facultat de Biologia, Universitat de Barcelona, Spain.
F J
FJ
López-Soriano
J A
JA
Fernández-López
M
M
Alemany
D002001:Adipose Tissue, Brown / Q000098:blood supply / Q000378:metabolism*; D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D005947:Glucose / Q000378:metabolism*; D008297:Male; D009929:Organ Size; D051381:Rats; D011919:Rats, Inbred Strains; D013217:Starvation / Q000378:metabolism*; D013997:Time Factors
D000596:Amino Acids; D005947:Glucose