[Role of disorders of pentosephosphate pathway of glucose oxidation in the pathogenesis of the arrest of fetal development in miscarriage].
Activity of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase, the enzymes participating in the pentose phosphate pathway of glucose oxidation was studied in the blood of 15 normal fetuses and 25 abortuses as well as in 80 females (20 with normally advancing pregnancy, 40 with the signs of discontinuation and 20 patients with spontaneous abortion developed during 24-26 weeks of gestation). The impact of abnormal pentose phosphate pathway of glucose oxidation on the pathogenesis of fetal development arrest in females with incompetent pregnancy was established.
Kuznetsova
V A
VA
Slobodin
V B
VB
Moreva
I V
IV
Sitnikova
O G
OG
D000022:Abortion, Spontaneous / Q000201:enzymology / Q000378:metabolism*; D000328:Adult; D005260:Female; D005313:Fetal Death / Q000209:etiology*; D005333:Fetus / Q000378:metabolism*; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism*; D006801:Humans; D010427:Pentose Phosphate Pathway; D010734:Phosphogluconate Dehydrogenase / Q000378:metabolism*; D011247:Pregnancy
D010734:Phosphogluconate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase
Rol' narusheniĭ pentozo-fosfatnogo puti okisleniia gliukozy v patologeneze zaderzhki razvitia ploda pri nevynashivanii beremennoti.