[Therapeutic approach to pulmonary embolism].
The purpose of this study is the retrospective evaluation of the treatment of 196 cases of pulmonary embolism. Therapeutic attitude was standardized. Intravenous heparin followed early on by oral anticoagulants remains the basic treatment of the majority of patients (74%). This treatment could be associated with: (1) Fibrinolysis with urokinase bolus at the time of massive pulmonary embolism with clinical and hemodynamic signs of shock (14%). No severe hemorrhagic complication was observed. 2) Inferior vena caval interruption in case of contraindications or failure of anticoagulation (29%). Only one death was observed in this study.
Service de Pneumologie, Hôpital Antoine-Béclère, Clamart.
C
C
Phlippoteau
P
P
Girard
D
D
Musset
F
F
Bridey
B
B
Millat
P
P
Petitpretz
G
G
Simonneau
P
P
Duroux
D000925:Anticoagulants / Q000627:therapeutic use*; D005342:Fibrinolysis; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D011655:Pulmonary Embolism / Q000188:drug therapy*; D012189:Retrospective Studies; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use
D000925:Anticoagulants; D006493:Heparin; D014568:Urokinase-Type Plasminogen Activator
Approche thérapeutique des embolies pulmonaires.