Altered agonist-activated 86Rb+ efflux from arteries in canine renal hypertension.
Basal rate constants for 86Rb+ efflux from renal arteries of renal hypertensive dogs were lower than those of control animals whereas no differences were found for coronary arteries. Norepinephrine produced parallel increases in efflux rate constants for hypertensive and control renal arteries, but serotonin produced smaller responses in hypertensive compared to control coronary arteries.
Bockus Research Institute, Graduate Hospital, Philadelphia, PA 19146.
R H
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Cox
R J
RJ
Bagshaw
D000818:Animals; D003331:Coronary Vessels / Q000378:metabolism; D004285:Dogs; D006978:Hypertension, Renovascular / Q000378:metabolism*; D066298:In Vitro Techniques; D009131:Muscle, Smooth, Vascular / Q000378:metabolism*; D009638:Norepinephrine / Q000494:pharmacology; D012077:Renal Artery / Q000378:metabolism; D012414:Rubidium Radioisotopes; D012701:Serotonin / Q000494:pharmacology
D012414:Rubidium Radioisotopes; D012701:Serotonin; D009638:Norepinephrine