Radiation-induced cerebral lesions in childhood.
Post-irradiation cerebral pathologies may appear in various forms from localized radiation necrosis to a plurifocal type or from local to diffuse vasculopathies. Contrary to the current prevalent opinion, these lesions are not rare in children since young nerve tissue is particularly sensitive to ionizing radiation. Given the seriousness of some of these lesions, the authors recommend careful evaluation of the risk involved in relation to the real necessity of administering irradiation therapy in childhood.
Institute of Neurosurgery, University of Pisa, Italy.
R
R
Cantini
W
W
Giorgetti
A M
AM
Valleriani
M
M
Burchianti
C
C
Amodeo
D001254:Astrocytoma / Q000000981:diagnostic imaging / Q000532:radiotherapy; D001927:Brain Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology*; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy; D002533:Cerebral Angiography; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000532:radiotherapy; D008579:Meningioma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000532:radiotherapy; D009336:Necrosis; D011832:Radiation Injuries; D014057:Tomography, X-Ray Computed