[Crohn disease--initial manifestation in the oral and anogenital area].
A case is reported of Crohn's disease in a 17-year-old patient. The initial manifestation was bipolar: the clinical features of macrocheilitis with swelling of the upper lip that had persisted for the last 6 months. The buccal tissue disclosed a cobblestone-appearance, combined with atypical fissures and rhagades in the anogenital region. Histopathological examination of lip and anogenital biopsy specimens revealed a granulomatous inflammatory reaction. Therefore, the clinical findings were interpreted as the primary manifestation of Crohn's disease. In the differential diagnosis Melkersson-Rosenthal's syndrome was also taken into consideration.
Gomez
R S
RS
Dermatologische Klinik und Poliklinik, Universität Erlangen-Nürnberg.
Ozen
I Y
IY
Peters
K P
KP
Simon
M
M
Hornstein
O P
OP
D000293:Adolescent; D002613:Cheilitis / Q000473:pathology*; D003424:Crohn Disease / Q000150:complications* / Q000473:pathology; D003937:Diagnosis, Differential; D005401:Fissure in Ano / Q000473:pathology; D006801:Humans; D008297:Male; D011349:Proctitis / Q000473:pathology*; D012867:Skin / Q000473:pathology
Morbus Crohn--Erstmanifestation im oralen und anogenitalen Bereich.