Effect of halothane anesthesia on mesenteric intralymphatic pressure in the rat.
The effect of halothane on mesenteric intralymphatic pressure was examined in 20 rats. Following administration of 1.5% halothane, lymph pressure decreased from a control value of 7.6 +/- 1.5cmH20 to 3.8 +/- 1.8cmH20. On the other hand, a lower concentration of halothane (1%) did not alter lymph pressure. In conjunction with earlier findings, these data suggest further that lymph propulsion is suppressed during halothane (greater than 1.5%) anesthesia.
Division of Dental Anesthesia, Hiroshima University Dental Hospital, Japan.
T
T
Takeshita
M
M
Kawahara
S
S
Akita
T
T
Moriyama
K
K
Fujii
M
M
Sinozaki
M
M
Morio
D000769:Anesthesia, Inhalation; D000818:Animals; D006221:Halothane / Q000633:toxicity*; D008196:Lymph / Q000378:metabolism*; D008208:Lymphatic System / Q000187:drug effects*; D008297:Male; D008643:Mesentery; D011312:Pressure; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D006221:Halothane