A kinetic hairpin transfer model for parvoviral DNA replication.
The DNAs encapsidated by parvoviruses show distinctly different patterns with respect to the ratio of plus-to-minus strands and sequence heterogeneity at the ends. A kinetic model, based on differential rates of hairpin transfer at 3' termini, is described and shown to account for all known parvoviral DNA distributions.
Department of Biology, Virginia Polytechnic Institute and State University, Blacksburg 24061.
K C
KC
Chen
J J
JJ
Tyson
M
M
Lederman
E R
ER
Stout
R C
RC
Bates
D001483:Base Sequence; D003198:Computer Simulation; D004261:DNA Replication; D004279:DNA, Viral / Q000235:genetics*; D007700:Kinetics; D008433:Mathematics; D008957:Models, Genetic; D010321:Parvoviridae / Q000235:genetics*; D013816:Thermodynamics
D004279:DNA, Viral