Age distribution of circulating alpha-interferon.
A sensitive radioimmunoassay showed that circulating alpha-interferon in the plasma of healthy individuals was low in children and reached the highest level in the young adult, then declined gradually with age. Circulating alpha-interferon was 0.201 +/- 0.059 ng/ml in males (n = 19) and 0.184 +/- 0.076 ng/ml in females (n = 14) at ages 30-39 years old. It was noted that circulating alpha-interferon was maintained up to a certain level even in elderly individuals.
Shiozawa
S
S
Department of Medicine, Kobe University School of Medicine, Japan.
Shiozawa
K
K
Shimizu
S
S
Tanaka
Y
Y
Morimoto
I
I
Kuroki
Y
Y
Yoshihara
R
R
Fujita
T
T
D000328:Adult; D000368:Aged; D000375:Aging / Q000097:blood*; D002648:Child; D005260:Female; D006801:Humans; D007370:Interferon Type I / Q000097:blood*; D008297:Male; D011863:Radioimmunoassay; D014407:Tumor Cells, Cultured
D007370:Interferon Type I