HTLV-I-associated myelopathy with adult T-cell leukemia.
We report a 42-year-old Japanese woman with HTLV-I-associated myelopathy (HAM) combined with adult T-cell leukemia (ATL). Combination of the 2 diseases has been extremely rare. The infrequency is explained by HLA types unique to each disease. Our patient suggests that the HAM-associated HLA haplotype does not prevent the development of ATL.
Kawai
H
H
First Department of Internal Medicine, School of Medicine, University of Tokushima, Japan.
Nishida
Y
Y
Takagi
M
M
Nakamura
K
K
Masuda
K
K
Saito
S
S
Shirakami
A
A
D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D015139:Blotting, Southern; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D006239:Haplotypes; D015368:Human T-lymphotropic virus 1 / Q000276:immunology; D006801:Humans; D015458:Leukemia, T-Cell / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D015493:Paraparesis, Tropical Spastic / Q000150:complications* / Q000175:diagnosis
D000914:Antibodies, Viral