Some new prazosin-like derivatives.
The preparation of a number of prazosin-like derivatives is reported. The new derivatives differ from the parent compound for the 2-side-chain which is represented by peculiar fragments of butyrophenone neuroleptics. The results of the pharmacological evaluation are also reported.
Rampa
A
A
Carrara
M
M
Zampiron
S
S
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D005260:Female; D007928:Lethal Dose 50; D051379:Mice; D011224:Prazosin / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000633:toxicity
D011224:Prazosin