Failure to find an association between ocular squamous cell carcinoma and class I antigens of the bovine major histocompatibility system.
We tested 53 cattle with ocular squamous cell carcinoma (cancer-eye) and 53 paired, matched controls for 25 class I antigens of the bovine major histocompatibility system. The most common antigen was W5 which was present in 40% of the animals with cancer-eye and 36% of the controls. There were no statistically significant differences in BoLA antigen frequency between cattle with and cattle without cancer-eye.
Department of Immunology, John Curtin School of Medical Research, Australian National University.
M J
MJ
Stear
P B
PB
Spradbrow
T J
TJ
Tierney
F W
FW
Nicholas
R A
RA
Bellows
D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000276:immunology / Q000662:veterinary*; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology*; D005134:Eye Neoplasms / Q000276:immunology / Q000662:veterinary*; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D006720:Homozygote
D015395:Histocompatibility Antigens Class I