Trixacarus caviae infection of guinea pigs with genetically determined differences in susceptibility to Trichostrongylus colubriformis infection.
Guinea pigs with genetically determined resistance or susceptibility to infection with the nematode parasite Trichostrongylus colubriformis were allowed to become infected with the sarcoptid mite Trixacarus caviae. Compared with nematode-susceptible guinea pigs, nematode-resistant animals had larger populations of mites and developed a more severe dermatitis, with greater mast cell hyperplasia and many more infiltrating eosinophils. The results suggest that animals bred for resistance to one parasite may have greater susceptibility to other parasites.
Rothwell
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Pope
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Collins
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D000818:Animals; D004198:Disease Susceptibility; D005260:Female; D006168:Guinea Pigs / Q000469:parasitology*; D007113:Immunity, Innate; D008924:Mite Infestations / Q000276:immunology / Q000662:veterinary*; D008925:Mites; D012376:Rodent Diseases / Q000276:immunology*; D014252:Trichostrongyloidiasis / Q000662:veterinary*; D014253:Trichostrongylosis / Q000276:immunology / Q000662:veterinary*