Relation of muscle cell contraction and calcium distribution in sarcomere.
A model of activation of muscle contraction has been proposed. It is based on calcium diffusion and binding to specific regulatory sites in a sarcomere. Calcium ions activate interactions of contractile proteins and thus the generation of force. The model quantifies the relation between calcium released from intracellular stores and the elicited force.
Poledna
J
J
Centre of Physiological Sciences, Slovak Academy of Sciences, Bratislava.
D000818:Animals; D001665:Binding Sites; D002118:Calcium / Q000378:metabolism*; D004058:Diffusion; D008954:Models, Biological; D009119:Muscle Contraction; D009210:Myofibrils / Q000502:physiology*; D009218:Myosins; D012518:Sarcomeres / Q000502:physiology*; D012519:Sarcoplasmic Reticulum / Q000502:physiology; D014336:Troponin / Q000378:metabolism
D014336:Troponin; D009218:Myosins; D002118:Calcium