Plasma pyridoxal 5'-phosphate concentration and dietary vitamin B-6 intake in free-living, low-income elderly people.
Free-living, elderly persons (aged greater than or equal to 60 y, n = 198) were recruited to determine the effects of age, sex, health status, dietary vitamin B-6 intakes, and B-6 supplement use on plasma pyridoxal 5'-phosphate (PLP). Vitamin B-6 intakes were determined from 3-d diet records; supplementation was based on self-reported brand and frequency data. Fasting blood samples were analyzed for PLP. Subjects were primarily low-income Caucasians. There was no linear relationship between dietary vitamin B-6 intake, age, sex or health status, and PLP while accounting for supplemental vitamin B-6 use. PLP, however, was negatively correlated with age (p less than 0.001) in individuals with PLP values between 32 and 90 nmol/L. Vitamin B-6 status was low (PLP less than 32 nmol/L) in 32% of this elderly population (n = 198) and could be attributed to low dietary vitamin B-6 intakes and/or the presence of health problems reported to alter vitamin B-6 status. This research suggests that low vitamin B-6 status is prevalent in low-income, elderly persons, especially those with multiple health problems.
Department of Family Resources and Human Development, Arizona State University, Tempe 85287-2502.
M M
MM
Manore
L A
LA
Vaughan
S S
SS
Carroll
J E
JE
Leklem
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism; D000886:Anthropometry; D004032:Diet; D005260:Female; D006801:Humans; D008297:Male; D011732:Pyridoxal Phosphate / Q000097:blood*; D011736:Pyridoxine / Q000008:administration & dosage*; D012737:Sex Factors
D011732:Pyridoxal Phosphate; D011736:Pyridoxine