Phosphatidylserine administration during postnatal development improves memory in adult mice.
Postnatal administration of an aqueous suspension of phosphatidylserine (BC-PS) to C57BL/6 mice resulted in improvement of memory processes in adulthood, as assessed in a passive avoidance task. These findings are discussed in terms of the effects of BC-PS on cholinergic mechanisms and of cholinergic patterns of this inbred strain.
Dipartimento di Genetica e Biologia Molecolare, Universitá di Roma, La Sapienza, Italy.
S
S
Fagioli
C
C
Castellano
A
A
Oliverio
F
F
Pavone
R
R
Populin
G
G
Toffano
D000818:Animals; D001362:Avoidance Learning; D005260:Female; D008568:Memory / Q000187:drug effects*; D051379:Mice; D008810:Mice, Inbred C57BL; D009043:Motor Activity; D010718:Phosphatidylserines / Q000008:administration & dosage / Q000494:pharmacology*; D011247:Pregnancy
D010718:Phosphatidylserines