[Effect of hyperoxia on systemic hemodynamics, microcirculation, and oxygen regimen in rats in replacement of massive blood loss by albumin].
Experiments were conducted on rats to study systemic hemodynamics, microcirculation, and oxygen regimen in the organism in replacement of massive blood loss with albumin solution in normo- and hyperoxia. The results suggest that in breathing oxygen conditions are created in the organism for fuller realization of the mechanism of compensatory increase of the minute circulation volume in replacement of blood loss by a blood substitute, as a result of which total oxygen consumption increases and microcirculation is restored more adequately.
N I
NI
Kochetygov
A D
AD
Dolgushina
A V
AV
Gorkun
D000418:Albumins / Q000627:therapeutic use*; D000818:Animals; D001802:Blood Substitutes / Q000627:therapeutic use*; D006439:Hemodynamics / Q000187:drug effects*; D006470:Hemorrhage / Q000188:drug therapy* / Q000503:physiopathology; D008833:Microcirculation / Q000187:drug effects* / Q000503:physiopathology; D010100:Oxygen / Q000494:pharmacology*; D051381:Rats
D000418:Albumins; D001802:Blood Substitutes; D010100:Oxygen
Vliianie giperoksii na sistemnuiu gemodinamiku, mikrotsirkuliatsiiu i kislorodnyĭ rezhim u krys pri vozmeshchenii massivnoĭ krovopoteri al'buminom.