Cutaneous vasculitis due to cyclophosphamide therapy for chronic lymphocytic leukemia.
A 55-year-old male with chronic lymphocytic leukemia developed a skin eruption after receiving oral cyclophosphamide. Subsequent rechallenge with parenteral cyclophosphamide led to recurrence of the skin lesions, which on biopsy were shown to be vasculitic in nature.
Queen Elizabeth Hospital, Woodville, SA.
R M
RM
Green
G J
GJ
Schapel
R E
RE
Sage
D000284:Administration, Oral; D002908:Chronic Disease; D003520:Cyclophosphamide / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007945:Leukemia, Lymphoid / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000139:chemically induced*
D003520:Cyclophosphamide