Two- and three-dimensional ultrastructure of endothelium and pericyte interdigitations in capillary of human granulation tissue.
Two- and three-dimensional electron microscopic observation in the immature capillary of the human granulation tissue revealed cytoplasmic interdigitations (CID) between the endothelium and the pericyte. These were composed of a cytoplasmic projection and indentation, and there was a gap space without basement membrane-like components between the two cell membranes. Plasmalemmal vesicles were frequently found locating beneath and/or attached to the cell membranes at the indentated side of the interdigitation. Two kinds of cytoplasmic interdigitation, each having a characteristic configuration, were demonstrated. The CID which was composed of a cytoplasmic projection from the endothelium to the pericyte had a dull-shaped cytoplasmic projection, while the CID which was composed of a cytoplasmic projection from the pericyte to the endothelium had a slender and long finger-like configuration.
S
S
Wakui
M
M
Furusato
M
M
Hasumura
M
M
Hori
H
H
Takahashi
Y
Y
Kano
S
S
Ushigome
D002196:Capillaries / Q000166:cytology / Q000502:physiology / Q000648:ultrastructure; D004730:Endothelium, Vascular / Q000166:cytology / Q000502:physiology / Q000648:ultrastructure*; D006097:Granulation Tissue / Q000098:blood supply*; D006801:Humans