Discrimination of human dorsal root ganglion cells by anti-fucosyl GM1 antibody.
Some neurons and surrounding satellite cells in human dorsal root ganglia were immunostained with rabbit IgM antibody against the ganglioside fucosyl GM1. They were not immunostained with the anti-GM1 antiserum. Immunohistochemical discrimination of neurons in human dorsal root ganglia by the anti-fucosyl GM1 antibody may give us an important clue to the functional identification of neurons conveying different modalities of sensation.
Department of Neurology, Faculty of Medicine, University of Tokyo, Japan.
S
S
Kusunoki
K
K
Inoue
M
M
Iwamori
Y
Y
Nagai
T
T
Mannen
D000818:Animals; D005643:Fucose / Q000378:metabolism*; D005677:G(M1) Ganglioside / Q000378:metabolism*; D005727:Ganglia, Spinal / Q000166:cytology / Q000378:metabolism*; D006801:Humans; D007150:Immunohistochemistry; D051381:Rats; D011919:Rats, Inbred Strains; D013045:Species Specificity
D005643:Fucose; D005677:G(M1) Ganglioside