Linkage analysis of French families with facioscapulohumeral muscular dystrophy.
Linkage analysis was undertaken in seven French families with facioscapulohumeral muscular dystrophy (FSHD). Six polymorphic DNA probes were studied, including random DNA sequences, coding sequences, and a hypervariable marker. No evidence for linkage of these probes to the disease was detected, and the results exclude probable location of the FSHD gene from three chromosomal regions (16p, proximal 19q, and 21q).
Laboratory of Physical Anthropology, Collège de France, Paris.
G
G
Lucotte
S
S
Berriche
M
M
Fardeau
D002874:Chromosome Mapping / Q000379:methods; D002885:Chromosomes, Human, Pair 16; D002888:Chromosomes, Human, Pair 19; D002891:Chromosomes, Human, Pair 21; D015342:DNA Probes; D003627:Data Interpretation, Statistical; D005602:France; D008040:Genetic Linkage; D006801:Humans; D009136:Muscular Dystrophies / Q000235:genetics* / Q000473:pathology
D015342:DNA Probes