Monitoring of therapy for deep vein thrombosis using magnetic resonance imaging.
Magnetic resonance imaging using limited-flip-angle, gradient refocused pulse sequences has been used to monitor the course of anticoagulant or fibrinolytic therapy for deep vein thrombosis in two patients. The findings demonstrate the capacity of this technique to delineate the extent of thrombosis and characterize changes in size in response to treatment. Advantages of this approach include high anatomic resolution, speed of examination and non-invasiveness, properties that make it well-suited to following the progress of therapy with potentially significant implications for improving treatment.
Department of Medicine, University of Rochester, New York 14642.
C W
CW
Francis
T H
TH
Foster
S
S
Totterman
B
B
Brenner
V J
VJ
Marder
R G
RG
Bryant
D000328:Adult; D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use*; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010690:Phlebography; D010960:Plasminogen Activators / Q000627:therapeutic use; D011994:Recombinant Proteins / Q000627:therapeutic use; D013924:Thrombophlebitis / Q000175:diagnosis* / Q000188:drug therapy
D000925:Anticoagulants; D005343:Fibrinolytic Agents; D011994:Recombinant Proteins; D006493:Heparin; D010960:Plasminogen Activators