[Comparative characteristics of the lipid composition of lipoproteins of the blood plasma and ascitic fluid in liver cirrhosis].
Comparison of phospholipid content in different fractions of lipoproteins of the ascitic fluid and blood plasma showed selective accumulation of high density lipoproteins (HDLP) in the ascitic fluid. The ascitic fluid HDLP differed from blood plasma HDLP in a larger fraction of triglycerides and cholesterol oleate. No significant difference was revealed in the lipoprotein (LP) low density lipid spectrum in the two fluids. The very low density LP (VLDLP) of the ascitic fluid differed from blood plasma VLDLP by higher ratios of phosphatidylcholine (PC) (sphingomyelin and PC) unesterified cholesterol; the PC in VLDLP of the ascitic fluid had a relatively higher content of linoleic and oleic acids. It is suggested that the detected differences are associated with dynamic insufficiency of lymph drainage in portal hypertension, as the result of which LP of intestinal genesis, spreading in the interstitium of the wall of the small intestine, enter the abdominal cavity by bypassing the blood plasma.
A B
AB
Kosukhin
P E
PE
Riudiger
B S
BS
Akhmetova
G N
GN
Andreev
D001202:Ascitic Fluid / Q000032:analysis*; D006801:Humans; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*; D008103:Liver Cirrhosis / Q000097:blood / Q000378:metabolism*
D008055:Lipids; D008074:Lipoproteins
Sravnitel'naia kharakteristika lipidnogo sostava lipoproteidov plazmy krovi i astsiticheskoĭ zhidkosti pri tsirrozakh pecheni.