Diabetes and hypertension. Blood pressure in clinical diabetic patients and a control population.
Blood pressure was recorded in a group of 514 randomly selected Swiss diabetic patients (267 men and 247 women; 164 early-onset and 350 late-onset diabetics) aged from 35 to 54 years. These patients were compared with a control group from a population survey in Switzerland (877 men and 850 women). Mean systolic pressure (+/- SD) in the diabetic population was 139.3 +/- 21 mm Hg as compared with 125.5 +/- 17 mm Hg among controls. Mean diastolic pressure was 85.4 +/- 12 mm Hg in diabetic subjects as compared with 79.1 +/- 12 mm Hg in controls. The difference was reduced by about 25% after adjustment for body mass, age, and sex; 30.7% of diabetic subjects as compared with 8.2% among controls were hypertensive. Sixty-two percent of the hypertensive diabetic patients and 45% of the hypertensive controls were receiving antihypertensive treatment. In a multivariate analysis, presence of proteinuria and larger body mass had an important influence on systolic and diastolic blood pressures and the risk of hypertension. Diabetes duration had a significant influence only on systolic blood pressure. Efforts are needed in the clinical and research field to limit and clarify the harmful effects of elevated blood pressure in diabetes.
University of Berne Medical School, Department of Internal Medicine, Switzerland.
A
A
Teuscher
M
M
Egger
J B
JB
Herman
D000328:Adult; D001794:Blood Pressure; D003925:Diabetic Angiopathies / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012727:Sex Characteristics