Meperidine to control shivering associated with platelet transfusion reaction.
Shivering may be part of a febrile non-haemolytic reaction to blood product transfusion. Shivering can increase oxygen consumption up to 500 per cent which may be detrimental to patients with decreased myocardial reserve. A case is presented of a reaction to platelet transfusion characterized by shivering, tachycardia and hypertension in a patient with a recent myocardial infarction in whom the metabolic and haemodynamic effects were considered to be potentially disastrous. Intravenous injection of meperidine was rapidly effective in treating these changes.
Friedlander
M
M
Department of Anaesthesia, St. Michael's Hospital, University of Toronto, Ontario.
Noble
W H
WH
D000328:Adult; D006801:Humans; D008297:Male; D008614:Meperidine / Q000627:therapeutic use*; D017713:Platelet Transfusion; D012768:Shivering / Q000187:drug effects*; D065227:Transfusion Reaction
D008614:Meperidine