[Value of correcting microcirculatory disorders of inflammatory foci in the treatment of infection].
Experience in the treatment of 94 patients with sepsis is discussed. Studies showed that microcirculatory disorders occurring around the inflammatory focus are among the main causes of insufficient efficacy of antibiotic therapy. For correction of the microcirculatory changes, the authors suggest (in addition to vasodilators, inhibitors of proteases and heparin used earlier for this purpose) transfusion of chilled plasma which is a antithrombin-III donator. As the result of such treatment mortality reduced from 45.8 to 16.7%.
Shoĭkhet
Ia N
IaN
Dederer
Iu M
IuM
Roshchev
I P
IP
D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007511:Ischemia / Q000209:etiology / Q000628:therapy*; D008168:Lung / Q000098:blood supply*; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D011014:Pneumonia / Q000150:complications / Q000628:therapy*; D012867:Skin / Q000098:blood supply*; D012874:Skin Diseases, Infectious / Q000150:complications / Q000628:therapy*
Znachenie likvidatsii mikrotsirkuliatornykh narusheniĭ v zone vospalite'lnogo ochaga pri lechenii sepsisa.