[Changes in production of platelet activating factor by adherent hepatocytes of mice with experimental liver failure].
It is thought that the platelet activating factor (PAF) enhances the immune response and inflammatory reaction. We studied the production of PAF from liver adherent cells. As a result, liver adherent cells produced PAF, when they were stimulated with calcium ionophore. In addition, when mice were treated with heat-killed Propionibacterium acnes and the mononuclear cells were infiltrated into the liver, a significantly larger amount of PAF was produced compared to normal mice.
Kioka
K
K
Mizoguchi
Y
Y
Ichikawa
Y
Y
Kuboi
H
H
Shin
T
T
Sakagami
Y
Y
Kobayashi
K
K
Morisawa
S
S
Yamamoto
S
S
D000208:Acute Disease; D000818:Animals; D008099:Liver / Q000378:metabolism*; D008107:Liver Diseases / Q000378:metabolism*; D008297:Male; D051379:Mice; D010972:Platelet Activating Factor / Q000096:biosynthesis*; D011425:Propionibacterium acnes / Q000276:immunology
D010972:Platelet Activating Factor