Chronic relapsing idiopathic polyneuropathy with primary axonal lesions.
Idiopathic polyradiculoneuropathy with primary axonal lesions is rarely encountered. Two cases are reported with a chronic relapsing course and a fatal outcome. Neuropathological examination of biopsied peripheral nerve in the two patients and in a necropsy case showed loss of myelinated fibres, but neither active demyelination nor inflammatory cells were observed. Acute and chronic relapsing axonal polyradiculoneuropathies appear to be two clinical forms of a peculiar entity different from GBS.
Department of Neurology, Hôpital du Haut-Levêque, Pessac, France.
J
J
Julien
C
C
Vital
A
A
Lagueny
X
X
Ferrer
C
C
Brechenmacher
D001369:Axons / Q000473:pathology*; D001706:Biopsy; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009413:Nerve Fibers, Myelinated / Q000473:pathology; D009416:Nerve Regeneration; D010543:Peroneal Nerve / Q000473:pathology; D011129:Polyradiculoneuropathy / Q000473:pathology*; D011782:Quadriplegia / Q000473:pathology; D012008:Recurrence; D012583:Schwann Cells / Q000473:pathology