[Thrombocytic hemostasis and the prostaglandin system at early stages of arterial hypertension].
In young patients with borderline arterial hypertension the system of pressor and depressor prostaglandins (PG) is activated with maintenance of their physiological proportion. In patients with I stage essential hypertension a considerable rise in the level of PGF2 alpha and thromboxane determines the system imbalance in the direction of the predominance of pressor components. The platelet hemostatic link in I stage essential hypertension is characterized by an increase in platelet aggregation activity which is mediated by the imbalance of the prostacyclin-thromboxane system in the direction to thromboxane.
V I
VI
Kolomiets
O Ia
OIa
Babak
T G
TG
Starchenko
B E
BE
Volos
D000328:Adult; D015237:Dinoprost / Q000097:blood*; D015232:Dinoprostone / Q000097:blood*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood*; D008297:Male; D010974:Platelet Aggregation; D013928:Thromboxane A2 / Q000097:blood; D013997:Time Factors
D013928:Thromboxane A2; D015237:Dinoprost; D015232:Dinoprostone
Trombotsitarnyĭ gemostaz i sistema prostanoidov na rannikh stadiiakh arterial'noĭ gipertonii.