Excimer laser ablation of the human lens at 308 nm with a fiber delivery system.
A 308 nm excimer laser has been used with a fiber delivery system to perform ablation of the human lens. Preliminary results demonstrate the system's ability to ablate lens nucleus and cortex selectively, preserving the anterior and posterior capsules. The total delivered energy necessary to ablate a human lens ranged from 35 to 63 joules. Laser tissue interaction and ablation rates were computed for the different components of the human lens (capsule, cortex, nucleus) for the operatively useful energy densities (fluences). Operative experience suggests that cortex and nucleus can be ablated while preserving the capsule if an adequate irrigation and aspiration system is developed. These results also suggest that this modality may be adequate for performing endocapsular cataract extraction. Laser tissue interactions were also computed at variable distances between the fiber tip and tissue. As this distance increased, the spread of the beam increased and a significant increase in energy was necessary to induce tissue ablation. This was due to the decrease in fluence with increasing distance to the target tissue and/or the absorption and scattering of the delivered energy within a short distance from the fiber tip by the ablated material. Evidence of a sonic effect was also present.
Ophthalmology Research Laboratory, Cedars-Sinai Medical Center, Los Angeles, California 90048.
E
E
Maguen
M
M
Martinez
W
W
Grundfest
T
T
Papaioannou
M
M
Berlin
A B
AB
Nesburn
D000368:Aged; D005336:Fiber Optic Technology / Q000295:instrumentation*; D006801:Humans; D053685:Laser Therapy; D007903:Lens Capsule, Crystalline / Q000473:pathology; D007904:Lens Cortex, Crystalline / Q000473:pathology; D007908:Lens, Crystalline / Q000601:surgery*