[Prognostic significance of total blood cholesterol level and the possibility of dietary correction of hypercholesterolemia in the population].
In a population of males aged 40-59 years, a routine epidemiological survey was performed, which was followed by a 5-year follow-up to examine the mortality rates and incidence of myocardial infarction and stroke treated by an active prophylactic measure program (Group 1) and conventional regimen (Group 2). The total cholesterol levels of 260 mg/dl or more were found to be of highly prognostic value to death from all causes, largely cardiovascular diseases, to development of myocardial infarction, stroke, and to higher risk of fatal cases of the diseases. It was ascertained that it was difficult to modify the dietary habits in subjects of mature age. By the end of the fifth follow-up year, the examined patients from Group 1 showed a reduction in the mean level of total cholesterol and hypercholesterolemia rates, following by a decrease in total and cardiovascular mortality by 6.5 and 5.7%, respectively, the incidence of myocardial infarction and stroke and the risk of death from these complications becoming lower.
Kalinina
A M
AM
Chazova
L V
LV
Pavlova
L I
LI
Shchepkin
V V
VV
Panfilova
O A
OA
D000328:Adult; D002784:Cholesterol / Q000097:blood*; D002791:Cholesterol, Dietary / Q000008:administration & dosage*; D003327:Coronary Disease / Q000209:etiology / Q000401:mortality / Q000517:prevention & control*; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications / Q000178:diet therapy*; D008297:Male; D008875:Middle Aged; D009031:Moscow; D011446:Prospective Studies; D012307:Risk Factors; D014505:Urban Population
D002791:Cholesterol, Dietary; D002784:Cholesterol
Prognosticheskaia znachimost urovnia obshchego kholesterina v krovi i vozmozhnost dieticheskoĭ korrektsii giperkholesterinemii v populiatsii.