Leiomyosarcoma of a lower limb presenting with multiple cranial nerve palsies.
Leiomyosarcoma is a relatively uncommon soft tissue sarcoma usually presenting as a mass at the primary site. It arises in the retroperitoneal region, in the cutaneous or subcutaneous tissue of the extremities or, less commonly, from a large vein. A case is described where a patient presented with unilateral third, fourth, and sixth cranial, and ophthalmic division of trigeminal nerve palsies in whom biopsy of a longstanding lower limb mass demonstrated leiomyosarcoma. The presentation of this type of pathology has not been described previously.
Shotton
J C
JC
Academic Surgical Unit, Royal Marsden Hospital, London, UK.
D000010:Abducens Nerve; D002908:Chronic Disease; D003389:Cranial Nerve Diseases / Q000175:diagnosis / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007866:Leg; D007890:Leiomyosarcoma / Q000150:complications / Q000175:diagnosis*; D008875:Middle Aged; D009886:Ophthalmoplegia / Q000175:diagnosis* / Q000209:etiology; D010243:Paralysis / Q000175:diagnosis* / Q000209:etiology; D012983:Soft Tissue Neoplasms / Q000150:complications / Q000175:diagnosis*; D014276:Trigeminal Nerve; D014321:Trochlear Nerve