Neurological and behavioral sequelae in children operated on for brain abscess.
In order to characterize neurological, intellectual and behavioral sequelae better after surgical treatment of brain abscess in childhood, 32 children were studied over a 10-year time span after treatment of a brain abscess. Depending on the clinical condition, surgical treatment consisted of simple aspiration through a burr hole or of total excision after craniotomy. There were only 3 postoperative deaths (9%). The scheduled time for long-term follow-up was 3 years after surgery. The patient assessment included information concerning the presence of seizures, accurate neurological examination, an EEG, and a battery of intellectual tests to evaluate the presence of behavioral-mental deficits. Late seizures developed in 7 of the 29 survivors. Five patients presented permanent hemiparesis after surgical treatment. It is noteworthy that the intellectual impairment observed was more severe in younger patients, while the behavioral disturbances were more marked in school-age children.
Department of Neurosurgery, Santobono Children's Hospital, Napoli, Italy.
A
A
Buonaguro
M
M
Colangelo
B
B
Daniele
G
G
Cantone
A
A
Ambrosio
D000293:Adolescent; D001922:Brain Abscess / Q000473:pathology / Q000601:surgery*; D002648:Child; D002653:Child Behavior Disorders / Q000209:etiology*; D002675:Child, Preschool; D004569:Electroencephalography; D004827:Epilepsy / Q000209:etiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D007223:Infant; D007360:Intelligence; D008297:Male; D009422:Nervous System Diseases / Q000209:etiology*; D011183:Postoperative Complications