Biochemical and hormonal parameters in patients with multiple trauma.
We measured amount, course and duration of different parameters in order to assess metabolic-endocrine changes in patients with multiple trauma and the final outcome. Injures were initially quantified according to the Injury Severity Score. Serum levels of lactate, creatinine, bilirubin, somatomedin and thyroid hormons were measured in 51 patients (39 survivors, 12 deceased patients) for six days following the injury. In addition, neopterin levels were measured in 26 patients (19 survivors, 7 deceased patients). The patients were devided into two groups (survivors vs non-survivors). Global Index Scores and Septic Severity Scores were significantly different at the 1% and 5% level (p less than 0.05 to p less than 0.01). The same statistical differences were shown for lactate, somatomedin, neopterin and thyroid hormones.
Institute of Anaesthesiology of the FAU Erlangen-Nürnberg, W.-Germany.
M
M
Brandl
E
E
Pscheidl
W
W
Amann
A
A
Barjasic
T
T
Pasch
D015415:Biomarkers; D001708:Biopterins / Q000031:analogs & derivatives / Q000097:blood; D006801:Humans; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D009104:Multiple Trauma / Q000097:blood*; D019798:Neopterin; D012189:Retrospective Studies; D013002:Somatomedins / Q000097:blood; D013954:Thyroglobulin / Q000097:blood; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D015415:Biomarkers; D007773:Lactates; D013002:Somatomedins; D014284:Triiodothyronine; D001708:Biopterins; D019344:Lactic Acid; D019798:Neopterin; D013972:Thyrotropin; D013954:Thyroglobulin; D013974:Thyroxine