A potent, tissue-selective, synthetic inhibitor of HMG-CoA reductase.
Balasubramanian
N
N
Cardiovascular Division, Bristol Myers Co., Wallingford, Connecticut 06492.
Brown
P J
PJ
Catt
J D
JD
Han
W T
WT
Parker
R A
RA
Sit
S Y
SY
Wright
J J
JJ
D000818:Animals; D000924:Anticholesteremic Agents / Q000138:chemical synthesis / Q000494:pharmacology; D002070:Butadienes / Q000138:chemical synthesis* / Q000494:pharmacology; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D011714:Pyrans / Q000138:chemical synthesis*; D011753:Pyrones / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats; D013329:Structure-Activity Relationship
D000924:Anticholesteremic Agents; D002070:Butadienes; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D011714:Pyrans; D011753:Pyrones; C060957:BMY 22089