[BVDU therapy in herpes corneae].
The authors report on the results of therapy with 0.1% BVDU eye drops in a pilot study involving 80 patients suffering from stellate, dendritic, and geographic keratitis. Tolerance of this drug was very good. Healing occurred in 66 patients (82.5%) within 14 days. In these patients re-epithelialization was complete after an average of 5.4 days. In 13 patients (16.3%) the lesion took more than 14 days to heal (mean 18.2 days). The therapy must therefore be considered as having failed in these cases. In one patient (1.2%) the treatment had to be discontinued, as his condition deteriorated during treatment with BVDU.
Klinik für Augenheilkunde des Bereiches Medizin, Wilhelm-Pieck-Universität Rostock.
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A
Benad
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Richter
D000998:Antiviral Agents / Q000008:administration & dosage*; D001973:Bromodeoxyuridine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D005260:Female; D006801:Humans; D007635:Keratitis, Dendritic / Q000188:drug therapy*; D008297:Male; D009883:Ophthalmic Solutions; D014945:Wound Healing / Q000187:drug effects
D000998:Antiviral Agents; D009883:Ophthalmic Solutions; C020235:brivudine; D001973:Bromodeoxyuridine
BVDU-Therapie bei Herpes corneae.