Argyrophil carcinoma of the breast: a cytologic, histochemical, and ultrastructural study of a case.
Aspirate from an argyrophil carcinoma ("carcinoid") of the breast showed malignant dispersed epithelial cells. With Diff-Quik, the cytoplasm was seen to be abundant, with prominent eosinophilic granularity. The nuclei were fairly uniform, round or oval, and eccentric and had a finely stippled chromatin pattern. On histology, the tumor appeared typical for argyrophil carcinoma, and staining with Grimelius for argyrophilic granules was positive. Membrane-bound neurosecretory granules were seen on electron microscopy.
Department of Cytology, Dundee Royal Infirmary, Dundee, United Kingdom.
K A
KA
Hussein
D S
DS
Sanders
P E
PE
Preece
S M
SM
Hunter
S M
SM
Nicoll
D000368:Aged; D001707:Biopsy, Needle; D001940:Breast / Q000648:ultrastructure*; D001943:Breast Neoplasms / Q000648:ultrastructure*; D002276:Carcinoid Tumor / Q000648:ultrastructure*; D004848:Epithelium / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000648:ultrastructure