Immunohistochemical evidence for convergence of GABA-containing and glycine-containing axon terminals on single spinal motoneurons of the rat.
GABA- and glycine-containing neuronal elements were visualized in the rat spinal cord by immunohistochemistry employing antisera raised against conjugated GABA and glycine. GABA- and glycine-like immunoreactivities were localized in axon terminals and neuronal perikarya. GABA- and glycine-like immunoreactive terminals were in synaptic contact with perikarya and dendrites of most spinal neurons. Single spinal motoneurons appeared to be in contact with GABA- or glycine-like immunoreactive terminals. These findings suggest that these neurons are regulated postsynaptically by both GABA and glycine.
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Yoshida
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Tanaka
D000818:Animals; D001369:Axons / Q000032:analysis*; D005998:Glycine / Q000032:analysis*; D008297:Male; D009046:Motor Neurons / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains; D013116:Spinal Cord / Q000032:analysis*; D013569:Synapses / Q000032:analysis; D005680:gamma-Aminobutyric Acid / Q000032:analysis*
D005680:gamma-Aminobutyric Acid; D005998:Glycine