Mycobacterium avium-Mycobacterium intracellulare infection limited to the skin and lymph nodes in patients with AIDS.
Three patients with AIDS who were taking 3'-azido-3'-deoxythymidine (AZT) developed cutaneous abscesses from which Mycobacterium avium-Mycobacterium intracellulare was isolated. Culture of multiple blood samples and bone marrow aspirate from all three patients revealed that the infection was not disseminated. This is a rare form of presentation for this infection in AIDS patients. We speculate that the antiviral drug AZT was responsible for the localization of disease.
Barbaro
D J
DJ
Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas 75235-8859.
Orcutt
V L
VL
Coldiron
B M
BM
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000188:drug therapy; D000328:Adult; D006801:Humans; D008198:Lymph Nodes / Q000382:microbiology*; D008206:Lymphatic Diseases / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D015269:Mycobacterium avium Complex / Q000302:isolation & purification; D015270:Mycobacterium avium-intracellulare Infection / Q000175:diagnosis / Q000209:etiology*; D012874:Skin Diseases, Infectious / Q000175:diagnosis / Q000209:etiology*; D015215:Zidovudine / Q000627:therapeutic use
D015215:Zidovudine