Coagulation equilibrium in bilharzial hepatic fibrosis.
Twenty patients with confirmed bilharzial hepatic fibrosis and similar number of matched normal controls were investigated for their plasma protein C activity, prothrombin time and partial thromboplastin time. The results showed marked decrease in plasma protein C activity together with the expected prolongation in prothrombin and partial thromboplastin times. Since protein C exhibits a controlling mechanism on haemostasis by inhibition of activated factor V, changes in plasma protein C activity will necessarily impart an effect on blood coagulation.
Shahine
M Y
MY
Moustafa
A S
AS
D006801:Humans; D008103:Liver Cirrhosis / Q000097:blood* / Q000209:etiology; D010314:Partial Thromboplastin Time; D011486:Protein C / Q000032:analysis*; D011517:Prothrombin Time; D012552:Schistosomiasis / Q000097:blood* / Q000150:complications
D011486:Protein C