[Treatment of acute diarrhea in infants and young children with a new formulated oral rehydration solution].
49 infants and children with acute diarrhea with mild to moderate dehydration have been rehydrated orally with a newly composed oral rehydration solution. This solution differs from the traditional WHO recommended rehydration solution in a lower sodium content of 60 mval/l and replacement of bicarbonate 25 mval/l by an equimolar amount of citrate. The taste of the solution was improved by addition of flavour. All infants and children - including 8 infants less than 3 months of age - were successfully rehydrated. The solution was well accepted; no side effects have been observed. The sodium content remained normal in all patients.
Universitätsklinik für Kinderheilkunde, Innsbruck.
J P
JP
Guggenbichler
B
B
Kogler
D001639:Bicarbonates / Q000008:administration & dosage*; D001835:Body Weight / Q000187:drug effects; D002675:Child, Preschool; D002951:Citrates / Q000008:administration & dosage; D019343:Citric Acid; D003968:Diarrhea, Infantile / Q000628:therapy*; D004305:Dose-Response Relationship, Drug; D005440:Fluid Therapy / Q000379:methods*; D005947:Glucose / Q000008:administration & dosage*; D005950:Glucose Solution, Hypertonic / Q000008:administration & dosage; D006801:Humans; D007223:Infant; D011189:Potassium Chloride / Q000008:administration & dosage*; D012965:Sodium Chloride / Q000008:administration & dosage*; D014882:Water-Electrolyte Balance / Q000187:drug effects
D001639:Bicarbonates; D002951:Citrates; D005950:Glucose Solution, Hypertonic; C044142:World Health Organization oral rehydration solution; D019343:Citric Acid; D012965:Sodium Chloride; D011189:Potassium Chloride; D005947:Glucose
Behandlung akuter Diarrhöen bei Säuglingen und Kleinkindern mit einer neu zusammengesetzten oralen Rehydrierungslösung.