A survey of the human T-cell lymphotropic virus type I (HTLV-I) in south-western Colombia.
To evaluate altitude of birthplace and residence as factors associated with geographic clustering of HTLV-I infection in Colombia, we sampled a total of 670 current residents of the South Pacific coastal lowland and of upland regions (Cali and environs) of the Valle and Cauca Provinces, located at an altitude of 3,100 ft. Among the 255 lowland study subjects, 4.3% had antibody against HTLV-I, compared to 0.9% of the 415 upland study subjects. A hypothesis emerging from this study is that the lower socio-economic status of lowland residents and associated diseases, particularly untreated syphilis and other sexually transmitted diseases, may explain the increased HTLV-I seropositivity rates in this population.
Environmental Epidemiology Branch, National Cancer Institute, Bethesda, MD 20892.
E M
EM
Maloney
H
H
Ramirez
A
A
Levin
W A
WA
Blattner
D000328:Adult; D000367:Age Factors; D000368:Aged; D044383:Black People; D001782:Blood Donors; D003105:Colombia; D005260:Female; D015481:HTLV-I Antibodies / Q000032:analysis*; D015490:HTLV-I Infections / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012749:Sexually Transmitted Diseases / Q000150:complications; D012959:Socioeconomic Factors
D015481:HTLV-I Antibodies