A novel method for removal of human immunodeficiency virus: filtration with porous polymeric membranes.
We propose a new method to rid solutions of a virus by using a novel regenerated multilayered structured cellulose membrane (BMM). When the filtrate of human immunodeficiency virus (HIV) preparation was obtained through BMM it showed no infectivity. Electron microscopic observation revealed that HIV was completely caught by the multilayers of the BMM. Conveniently, BMM was seldomly found to adsorb protein molecules and also to have a high filtration rate. These characteristics may have a use in the removal of other variously sized pathogenic agents from plasma.
Hamamoto
Y
Y
Department of Virology and Parasitology, Yamaguchi University School of Medicine, Japan.
Harada
S
S
Kobayashi
S
S
Yamaguchi
K
K
Iijima
H
H
Manabe
S
S
Tsurumi
T
T
Aizawa
H
H
Yamamoto
N
N
D002478:Cells, Cultured; D005374:Filtration / Q000379:methods*; D006678:HIV / Q000302:isolation & purification*; D015488:HIV Antigens / Q000032:analysis; D008567:Membranes, Artificial; D008854:Microscopy, Electron; D010539:Permeability; D011108:Polymers
D015488:HIV Antigens; D008567:Membranes, Artificial; D011108:Polymers