Histochemical study of superoxide dismutase in the ovary of the rat during the oestrous cycle.
Superoxide dismutase, an enzyme which causes the dismutation of superoxide free radical anions to generate hydrogen peroxide, has been localized in the rat ovary. The negative-staining method was used to provide photo-induced reduction of nitro-blue tetrazolium in cryostat sections of rat ovaries for histochemical localization of superoxide dismutase. Superoxide dismutase was found in growing follicles, the membrane granulosa of Graafian follicles, ovulated follicles and blood vessels. It is suggested that superoxide dismutase may play a role in regulating follicular development, ovulation and luteal functions.
School of Life Sciences, Devi Ahilya Vishwavidyalaya, Indore, M.P., India.
M
M
Laloraya
G P
GP
Kumar
M M
MM
Laloraya
D000818:Animals; D004971:Estrus / Q000378:metabolism*; D005260:Female; D006651:Histocytochemistry; D010053:Ovary / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains; D013482:Superoxide Dismutase / Q000032:analysis*
D013482:Superoxide Dismutase