[Evaluation of the excretory function of the liver in inflammatory diseases of the biliary tract (data of radioimmunologic analysis of cholylglycine level)].
Radioimmunoassays of ++choleglycine in 41 healthy donors, 37 patients with gastroduodenal diseases and 41 ones with inflammatory diseases of the bile ducts have revealed that impaired excretory function of the liver is associated with a reduced coefficient of the bile acid extraction and a decreased bactericidal activity of the bile. The latter fact is conducive to active growth of microorganisms in the bile and thus promotes postoperative septic complications. Early detection of cholestasis resultant from impaired excretory function with the use of choleglycine radioimmunoassays permits administration of early measures to restore the bile passage and of rational antibacterial therapy to prevent postoperative pyoseptic complications.
Buianov
V M
VM
Orduian
S L
SL
Gidzev
M Sh
MSh
Kasimov
A O
AO
D000328:Adult; D000368:Aged; D002761:Cholangitis / Q000503:physiopathology*; D002764:Cholecystitis / Q000503:physiopathology*; D006000:Glycocholic Acid / Q000097:blood / Q000378:metabolism*; D006801:Humans; D008099:Liver / Q000378:metabolism*; D008111:Liver Function Tests; D008875:Middle Aged; D011863:Radioimmunoassay
D006000:Glycocholic Acid
Otsenka ékskretornoĭ funktsii pecheni pri vospalite'lnykh zabo- levaniiakh zhelchevyvodiashchikh puteĭ (po dannym radioimmuno- logicheskogo issledovaniia urovnia kholeglitsina).