In vitro adherence of bovine erythrocytes infected with Babesia bovis to thrombospondin and laminin.
This study was undertaken to examine how eight putative adhesive agents bound to plastic surfaces affected the capacity of bovine erythrocytes, infected with either virulent or avirulent strains of Babesia bovis, to adhere in vitro. Thrombospondin (TSP) induced B. bovis-infected bovine erythrocytes to adhere and adherence was augmented when the infected blood was cultured for 24 h before the assay. Moreover, TSP also caused erythrocytes infected with avirulent strains of B. bovis to adhere to plastic in vitro. Laminin promoted the adherence of infected, and to a lesser extent, of uninfected erythrocytes.
Parrodi
F
F
Wright
I G
IG
Bourne
A S
AS
Dobson
C
C
D000818:Animals; D001403:Babesia / Q000502:physiology*; D001792:Blood Platelets / Q000378:metabolism*; D002417:Cattle; D002448:Cell Adhesion; D004912:Erythrocytes / Q000378:metabolism / Q000469:parasitology*; D007797:Laminin / Q000378:metabolism*; D008562:Membrane Glycoproteins / Q000378:metabolism*; D019699:Thrombospondins
D007797:Laminin; D008562:Membrane Glycoproteins; D019699:Thrombospondins