A temporal bone preparation for the study of cochlear micromechanics at the cellular level.
An in vitro preparation of the guinea pig temporal bone was developed for studying the micromechanical behaviour of the cochlea. The preparation consists of the cochlea opened at the apex, allowing observation of cellular structures within the cochlear partition with an optical sectioning microscope and measurements of cellular vibration with laser interferometry. The middle ear ossicles and the tympanic membrane are left intact as well as the bony part of the external auditory canal, which is used for delivering a sound stimulus to the cochlea.
Department of Physiology II, Karolinska Institute, Stockholm, Sweden.
M
M
Ulfendahl
A
A
Flock
S M
SM
Khanna
D000161:Acoustic Stimulation; D000818:Animals; D003051:Cochlea / Q000166:cytology / Q000502:physiology*; D004424:Ear Canal / Q000502:physiology*; D004432:Ear, Middle / Q000502:physiology*; D006168:Guinea Pigs; D066298:In Vitro Techniques; D013701:Temporal Bone / Q000601:surgery*; D014732:Vibration