Prenatal diagnosis of 45,X/46,XX mosaicism in the fetus. Should the pregnancy be terminated?
45,X/46,XX True mosaicism was found in the amniotic fluid cell culture study in our patient and was confirmed by rapid fetal blood karyotyping. Elective termination of the pregnancy revealed a morphologically normal female fetus with true mosaicism but no features of Turner's syndrome.
Department of Obstetrics and Gynaecology, North Devon District Hospital, Barnstaple, U.K.
R
R
Kulkarni
J
J
Hawkins
W P
WP
Bradford
D000032:Abortion, Therapeutic; D000328:Adult; D005260:Female; D006801:Humans; D007621:Karyotyping; D008423:Maternal Age; D009030:Mosaicism; D011247:Pregnancy; D018566:Pregnancy, High-Risk; D011296:Prenatal Diagnosis; D014424:Turner Syndrome / Q000175:diagnosis*