[The effect of acetylsalicylic acid on gastric transmural potential difference in healthy children and in children with inflammatory diseases].
The transmural potential difference (tpd) of the gastric mucosa was investigated in relation to age and sex of the patients. The administration of acetylsalicylic acid in healthy children causes no significant decrease in gastric potential difference. In children with acute of chronic inflammatory diseases (elevated blood sedimentation velocity) the tpd was found to be increased compared with normal controls. After local ASA application a temporary, significant decrease of the tpd to normal values could be observed.
Klinik für Kindermedizin, Ernst-Moritz-Arndt-Universität Greifswald.
A
A
König
K
K
Jährig
N
N
Nikolaides
D000208:Acute Disease; D001241:Aspirin / Q000009:adverse effects* / Q000627:therapeutic use; D001799:Blood Sedimentation; D002648:Child; D002675:Child, Preschool; D005260:Female; D005750:Gastric Juice / Q000187:drug effects; D005753:Gastric Mucosa / Q000187:drug effects*; D006801:Humans; D007249:Inflammation / Q000188:drug therapy*; D008297:Male; D008564:Membrane Potentials / Q000187:drug effects; D012307:Risk Factors; D014882:Water-Electrolyte Balance / Q000187:drug effects
D001241:Aspirin
Der Einfluss von Azetylsalizylsäure (ASS) auf die gastrale transmurale Potentialdifferenz (tPD) bei gesunden Kindern und Kindern mit entzündlichen Erkrankungen.