Adrenaline-mediated glycogenolysis in different skeletal muscle fibre types in the anaesthetized rat.
The effect of adrenaline infusion on glycogen breakdown in different muscle fibres types in resting extensor digitorum longus (EDL) and soleus was investigated with histochemical methods. During adrenaline infusion the glycogen content in type IIB and type IIA fibres in EDL, as measured in PAS-stained sections, decreased 24.5% and 11.5% respectively. The glycogen content in type I fibres in EDL and in type I, type IIA and T-fibres in soleus did not change during adrenaline infusion. The present study shows that adrenaline infusion has different effects on glycogen breakdown in the different fibre types in EDL and a different effect on type IIA fibres in EDL and soleus. So far, the reason for these differences is unknown.
Norwegian College of Physical Education and Sport, Oslo, Norway.
J
J
Jensen
H A
HA
Dahl
P K
PK
Opstad
D000818:Animals; D004837:Epinephrine / Q000008:administration & dosage*; D006003:Glycogen / Q000378:metabolism*; D006651:Histocytochemistry; D007262:Infusions, Intravenous; D008297:Male; D009132:Muscles / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D006003:Glycogen; D004837:Epinephrine