Critical fusion frequency in MS during mild induced hyperthermia.
By raising the body temperature of 0.5 degrees C the critical fusion frequency of a flickering light increases in normal subjects but decreases in multiple sclerosis (MS) patients. The change was present in 14 patients with definite MS and in 5 of 10 patients with probable MS. No clinical worsening was observed during the procedure or in the following hours.
Accornero
N
N
Department of Neurology, La Sapienza, University of Rome, Italy.
De Vito
G
G
Rotunno
A
A
Perugino
U
U
Manfredi
M
M
D000328:Adult; D001831:Body Temperature; D002940:Circadian Rhythm; D005074:Evoked Potentials, Visual; D005260:Female; D005425:Flicker Fusion; D006801:Humans; D006979:Hyperthermia, Induced; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000503:physiopathology*; D009902:Optic Neuritis / Q000503:physiopathology