[Features of contraction of various sections of the left ventricle of an intact heart upon the action of inotropic factors].
In anesthetized dogs, the effects of adrenaline and CaCl2 were studied by means of measuring intramural tension in the left ventricle wall (LV) and in the apex. The inotropic effect involved an increase in the ratio between the velocity of the tension growth in isovolumic phase and the maximum tension of this contraction, the ratio increasing more slowly in the apex than in the LV. This can be due to that the inotropic factors induce a greater growth of intramural tension in the apex than in the LV.
A M
AM
Chernysh
F E
FE
Farber
D000818:Animals; D002122:Calcium Chloride / Q000494:pharmacology; D002316:Cardiotonic Agents / Q000494:pharmacology*; D004285:Dogs; D004562:Electrocardiography; D004837:Epinephrine / Q000494:pharmacology; D005260:Female; D006321:Heart / Q000187:drug effects; D006439:Hemodynamics; D008297:Male; D009200:Myocardial Contraction / Q000187:drug effects*; D016276:Ventricular Function
D002316:Cardiotonic Agents; D002122:Calcium Chloride; D004837:Epinephrine
Osobennosti sokrashcheniia razlichnykh otdelov levogo zheludochka intaktnogo serdtsa pri deĭstvii inotropnykh faktorov.