Microcomputer programs for complex epidemiologic procedures. II. Test for equality and trend of adjusted rates.
The microcomputer program presented in Part I of this series (M. H. Dong, Comput. Biomed. Res. 22, 349 (1989)) is useful for computing adjusted excess rates. That program, however, does not provide a means for a quantitative analysis of the adjusted rates computed for the categories of a risk factor. At times it is crucial for us to determine whether after adjustment a factor exerts a dose-response effect that is statistically significant. Recently a hypothesis test for analyzing such an effect has been reported. The test is based on score statistics obtained directly from a product model assumed for the excess rate. The objective of this second part is to continue to make available a microcomputer program that has been written to implement the computation of these score statistics, which likewise entails a complex and lengthy iterative procedure. In this communication the test is described and the application of the microcomputer program is illustrated.
Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Rockville, Maryland 20857.
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D001699:Biometry; D004812:Epidemiologic Methods; D006801:Humans; D009017:Morbidity; D009026:Mortality; D012307:Risk Factors; D012984:Software