Self-complementary regions in human albumin mRNA encode important structural regions within the human albumin protein.
An analysis of the human albumin mRNA structure revealed a nonrandom distribution of self-complementary regions within the mRNA. The majority of these self-complementary mRNA stretches encode important structural regions of the human albumin protein. The amino acids contained within these regions of the protein exhibit a high degree of hydrophobic complementarity which could influence local protein conformation and contribute to the biological importance of the protein structures.
Antiviral Chemotherapy, Schering-Plough Corporation, Bloomfield, NJ 07003.
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D000418:Albumins / Q000235:genetics* / Q000648:ultrastructure; D000595:Amino Acid Sequence; D006801:Humans; D006860:Hydrogen Bonding; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D011487:Protein Conformation; D012333:RNA, Messenger / Q000235:genetics* / Q000648:ultrastructure
D000418:Albumins; D012333:RNA, Messenger