Effects of gustation and gastric loading on rapid calorie metering in rats.
On gustation/intubation of nutritive sucrose or glucose solution, both ad lib and meal-time rats reduced their subsequent 1 hr calorie intake via stock diet. But gustation/intubation of calorically-inert water had no effect on 1 hr calorie intake of either group of rats. In contrast, on tasting calorically-inert but sweet saccharin, the 1 hr intake of meal-time rats was reduced, though not the intake of ad lib rats. However, on intubation of saccharin solution no reduction in 1 hr intake was shown by either meal-time or ad lib rats. Quinine also showed differential effects on calorie intake. On intubation, but not on gustation of quinine, both ad lib and meal-time rats evidenced increase in their 1 hr calorie intake. Daily (24 hr) calorie intake via stock diet of ad lib rats, in contrast to 1 hr intake was unaffected by gustation/intubation of any test solution, including nutritive sucrose and glucose. Meal-time rats daily (3 hr) intake, on the other hand, was similar to 1 hr calorie intake following test solution treatment. It was reduced on gustation/intubation of calorically-rich solution as well as on tasting the sweet, but calorically-inert saccharin. Taste/intubation of quinine did not cause any change in daily calorie intake of either ad lib or meal-time rats.
Department of Physiology, St. John's Medical College, Karnataka, India.
E
E
Prabhakar
B S
BS
Rao
D000284:Administration, Oral; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D002149:Energy Intake / Q000187:drug effects*; D005247:Feeding Behavior / Q000187:drug effects / Q000502:physiology*; D005947:Glucose / Q000008:administration & dosage / Q000494:pharmacology; D007441:Intubation, Gastrointestinal; D008297:Male; D011803:Quinine / Q000008:administration & dosage / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D012439:Saccharin / Q000008:administration & dosage / Q000494:pharmacology; D013395:Sucrose / Q000008:administration & dosage / Q000494:pharmacology; D013649:Taste / Q000502:physiology*
D013395:Sucrose; D011803:Quinine; D012439:Saccharin; D005947:Glucose