Midtrimester amniocentesis: ten year experience in South Dakota.
Amniocentesis was begun as a clinical service by the Department of OB/GYN of the School of Medicine in 1978 through the Genetics Laboratory. The experience gained over the subsequent ten years and 1275 studies is detailed. An incidence of 2.9% abnormal karyotype to amniocentesis was found. Genetic counseling with regard to amniocentesis is recommended for women of 35 years or older with a positive family history.
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D000649:Amniocentesis; D002869:Chromosome Aberrations / Q000175:diagnosis*; D025063:Chromosome Disorders; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D006801:Humans; D007621:Karyotyping; D008423:Maternal Age; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D018566:Pregnancy, High-Risk; D012189:Retrospective Studies; D013023:South Dakota