Studies of neutralizing properties of antacid preparations. Part 5: Dissolution kinetics of dihydroxyaluminum aminoacetate.
The acid dissolution process of dihydroxyaluminum aminoacetate (1) has been studied by pH-stat method. The neutralization reaction was examined by monitoring the appearance of aluminum ion and aminoacetic acid in the reaction medium. The Weibull distribution function was applied to the quantitative interpretation of neutralization rate data. The mechanism of acid neutralization of 1 is discussed.
Department of Inorganic and Analytical Chemistry, K. Marcinkowski Academy of Medicine, Poznań, Poland.
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D000536:Aluminum Hydroxide / Q000032:analysis*; D000863:Antacids / Q000032:analysis*; D055598:Chemical Phenomena; D002621:Chemistry; D005998:Glycine / Q000031:analogs & derivatives* / Q000032:analysis; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D012995:Solubility
D000863:Antacids; D000536:Aluminum Hydroxide; C007420:dihydroxyaluminum aminoacetate; D005998:Glycine