Atracurium overdose in a small infant.
An error in setting a syringe driver caused a 2.75 kg infant to receive 37 mg atracurium over 75 minutes. Clinically full recovery of muscle power had returned spontaneously 135 minutes after the infusion was stopped. The child suffered no ill effects. Assay of blood and urine for atracurium and laudanosine confirmed rapid clearance of the drug.
Department of Anaesthesia, Manchester Royal Infirmary.
A J
AJ
Charlton
N J
NJ
Harper
D
D
Edwards
A C
AC
Wilson
D001279:Atracurium / Q000097:blood / Q000506:poisoning*; D005260:Female; D006801:Humans; D007223:Infant; D007546:Isoquinolines / Q000097:blood; D008508:Medication Errors; D009892:Opium / Q000097:blood
D007546:Isoquinolines; D001279:Atracurium; D009892:Opium; C001522:laudanosine