Dengue fever in American military personnel in the Philippines: clinical observations on hospitalized patients during a 1984 epidemic.
From June - August, 1984, 24 American military personnel were hospitalized with dengue (DEN) at Clark Air Base in the Philippines. Their infections were confirmed by serology using the hemagglutination-inhibition test and/or by virus isolation in Aedes pseudoscutellaris cell cultures. Most of the patients had a secondary type of antibody response probably reflecting prior vaccination against yellow fever. Three serotypes of DEN virus were isolated; 7 isolates of DEN 1, 4 isolates of DEN 3 and 3 isolates of DEN 2. All of the patients were Caucasian males between the ages of 20-43 years. All of the cases were clinically diagnosed as classical dengue fever. A platelet count of less than or equal to 100,000/microliters was a common finding (83.3%); however, hemoconcentration was not documented. Other major findings were the occurrence of mild hypotension (62.5%) and petechiae (37.5%). One patient presented with shock and upper gastrointestinal bleeding, but his diagnosis was complicated by a history of epigastric pain and use of aspirin. Although all of the patients fully recovered, the severity of illness was clearly documented by the average-length of hospitalization (5.9 days) and average time absent from work (8.7 days).
U.S. Naval Medical Research Unit No. 2, APO San Francisco, California 96528-5000.
C G
CG
Hayes
T F
TF
O'Rourke
V
V
Fogelman
D D
DD
Leavengood
G
G
Crow
M M
MM
Albersmeyer
D000328:Adult; D003715:Dengue / Q000097:blood / Q000453:epidemiology* / Q000503:physiopathology; D003716:Dengue Virus / Q000302:isolation & purification; D004196:Disease Outbreaks; D006801:Humans; D007902:Length of Stay; D008297:Male; D008889:Military Personnel; D010679:Philippines