Effect of vitamin E on red blood cell preservation.
The effect of exogenous vitamin E (2.1 mg/100 ml) was determined on the preservation of red blood cell integrity (PCV and RBC counts) during long-term storage. Cells from healthy human blood donors, normal rats and rats raised on a vitamin E-deficient diet were stored in CE medium at 4 degrees C for 40-60 days. The addition of vitamin E to the CE medium protected normal rat RBC and those from vitamin E-deficient animals to even a larger extent. Neither the PVC nor RBC count in human blood changed during storage for up to 60 days and no effect of exogenous vitamin E was demonstrable.
Departamento de Patologia Médica, Universidade Federal do Paraná, Curitiba, Brasil.
M S
MS
Leonart
A M
AM
Weffort-Santos
E M
EM
Muñoz
I H
IH
Higuti
V A
VA
Fortes
A J
AJ
Nascimento
D000818:Animals; D001793:Blood Preservation / Q000379:methods*; D003470:Culture Media / Q000032:analysis; D004906:Erythrocyte Count; D004912:Erythrocytes / Q000187:drug effects*; D006400:Hematocrit; D006801:Humans; D051381:Rats; D014810:Vitamin E / Q000494:pharmacology*; D014811:Vitamin E Deficiency / Q000097:blood*
D003470:Culture Media; D014810:Vitamin E