Biologic theories of aging.
Many theories have been proposed to explain aging. Currently, the most important theories include genetic control, deterioration of the immune system, somatic mutation, accumulated damage by free radicals, cross-linkage of macromolecules, and metabolic causes. While no single theory accounts for all of the observations about aging, recent research suggests that the primary process is under genetic control, with contributions from environmental factors.
Goldstein
S
S
University of Arkansas for Medical Sciences, College of Medicine, Little Rock.
Gallo
J J
JJ
Reichel
W
W
D000375:Aging / Q000235:genetics / Q000276:immunology / Q000378:metabolism; D000818:Animals; D005609:Free Radicals; D006801:Humans; D008954:Models, Biological; D009154:Mutation
D005609:Free Radicals