Isolation and primary structure of the C-peptide of proinsulin from the European eel (Anguilla anguilla).
1. The primary structure of the C-peptide of proinsulin from the European eel has been established as: DVEPLLGFLSPKSGQENEVDDFPYKGQGEL. The peptide was isolated from the extract of eel pancreas in a yield that was approximately equimolar with insulin. A comparison with the predicted structures of C-peptides from other teleost fishes has identified a domain in the central region of the peptide that has been more highly conserved than the rest of the molecule.
Conlon
J M
JM
Clinical Research Group for Gastrointestinal Endocrinology, Max-Planck-Gesellschaft, University of Göttingen, FRG.
Thim
L
L
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000811:Anguilla / Q000378:metabolism*; D000818:Animals; D002096:C-Peptide / Q000032:analysis / Q000302:isolation & purification*; D005399:Fishes / Q000378:metabolism; D006801:Humans; D008969:Molecular Sequence Data; D010179:Pancreas / Q000032:analysis
D000596:Amino Acids; D002096:C-Peptide