Patch testing in prurigo nodularis.
32 patients with prurigo nodularis evaluated at the Mayo Clinic from 1975 to 1987 have been patch tested for sensitivity to appropriate allergen series; 25 of these had relevant positive reactions and subsequent follow-up to 5 to 14 years was available for 11. 6 patients had persistent disease and 5 had resolution or marked improvement. 3 of these latter patients noted a strong positive correlation between improvement and avoidance of contact allergens. Screening for contact sensitivity may be helpful in the management of this refractory dermatosis, particularly if there is a coexistent dermatitis.
Department of Dermatology, Mayo Clinic, Rochester, Minnesota.
B D
BD
Zelickson
M T
MT
McEvoy
A F
AF
Fransway
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000485:Allergens / Q000276:immunology; D001706:Biopsy; D003877:Dermatitis, Contact / Q000276:immunology*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D011536:Prurigo / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology; D012882:Skin Tests
D000305:Adrenal Cortex Hormones; D000485:Allergens