Clinical differences in spinal opioid efficacy.
The case report describes a patient who presented with two simultaneously-occurring but distinct pain syndromes. Epidural morphine controlled the pain from the abdominoperineal resection, while the pain from a deep venous thrombosis was not masked. Such differential effects of epidural morphine on pain of varying origin supports physiological observations on the specificity of the site of action of spinal opioids.
Organowski
S
S
Department of Anaesthesia, University of Saskatchewan, University Hospital Saskatoon.
Duncan
P G
PG
D015360:Analgesia, Epidural; D005260:Female; D006801:Humans; D008875:Middle Aged; D009020:Morphine / Q000627:therapeutic use*; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D010149:Postoperative Pain / Q000188:drug therapy*; D013924:Thrombophlebitis / Q000503:physiopathology*
D009020:Morphine