[Injection of gene p53 into the pronuclei of mouse zygotes].
Attempts to transfer gene p53 via pAT153 vector to the mouse genome are described. Transgenic mice were obtained that carried sequences homologous to the pAT153 only. No transmission of foreign nucleotide sequences to progeny was observed.
Sergienko
V G
VG
Slezinger
M S
MS
Kuzin
B A
BA
D000818:Animals; D001483:Base Sequence; D002467:Cell Nucleus / Q000648:ultrastructure*; D004247:DNA / Q000235:genetics; D005260:Female; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008822:Mice, Transgenic / Q000235:genetics*; D009857:Oncogenes; D010957:Plasmids; D013077:Sperm Head / Q000648:ultrastructure*; D013084:Sperm-Ovum Interactions; D013094:Spermatozoa / Q000648:ultrastructure*; D014162:Transfection; D015053:Zygote / Q000648:ultrastructure*
D004247:DNA
In''ektsiia gena p53 v pronukleusy zigot mysheĭ.