Relation of muscle cell contraction and calcium distribution in sarcomere.
A model of activation of muscle contraction has been proposed. It is based on calcium diffusion and binding to specific regulatory sites in a sarcomere. Calcium ions activate interactions of contractile proteins and thus the generation of force. The model quantifies the relation between calcium released from intracellular stores and the elicited force.
Centre of Physiological Sciences, Slovak Academy of Sciences, Bratislava.
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Poledna
D000818:Animals; D001665:Binding Sites; D002118:Calcium / Q000378:metabolism*; D004058:Diffusion; D008954:Models, Biological; D009119:Muscle Contraction; D009210:Myofibrils / Q000502:physiology*; D009218:Myosins; D012518:Sarcomeres / Q000502:physiology*; D012519:Sarcoplasmic Reticulum / Q000502:physiology; D014336:Troponin / Q000378:metabolism
D014336:Troponin; D009218:Myosins; D002118:Calcium