Caffeinated beverages and low birthweight: a case-control study.
A case-control study, examining the effect of first trimester maternal caffeine consumption on low birthweight, was performed in the Kaiser Permanent Medical Care Program. Heavy consumption (greater than 3 servings/day) of coffee, cola and greater than 300 mg/day of caffeine from all sources (coffee, tea and cola) was associated with a marginally increased risk of low birthweight. Our data support previous findings of a modest effect of caffeine consumption on fetal growth.
Division of Research, Kaiser Permanente Medical Care Program, Oakland, CA 94611.
B J
BJ
Caan
M K
MK
Goldhaber
D000328:Adult; D002110:Caffeine / Q000009:adverse effects*; D005314:Embryonic and Fetal Development / Q000187:drug effects*; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D011247:Pregnancy; D012307:Risk Factors
D002110:Caffeine