New linkage findings in affective disorders.
Identification of single-gene forms of manic-depressive illness, through linkage demonstrations in pedigrees, offers important opportunities for identification of pathophysiological mechanisms, and for genetic counseling in families with a valid marker of vulnerability.
Gershon
E S
ES
Clinical Neurogenetics Branch, National Institute of Mental Health, Bethesda, MD 20892.
D002880:Chromosomes, Human, Pair 11; D008040:Genetic Linkage; D006801:Humans; D019964:Mood Disorders / Q000235:genetics*; D014960:X Chromosome