Experimental infection of baboons (Papio cynocephalus anubis) with Chlamydia pneumoniae strain 'TWAR'.
Two infant baboons (Papio cynocephalus anubis) were inoculated with Chlamydia pneumoniae strain 'TWAR', one in the conjunctiva, nasopharynx and oropharynx, the other in the trachea. Both remained well during 8 weeks of observation. C. pneumoniae infection persisted for at least 8 weeks after inoculation. Chlamydia pneumoniae seems to be of low virulence in baboons and capable of causing chronic infection.
Department of Epidemiology, University of Washington, Seattle 98195.
T A
TA
Bell
C C
CC
Kuo
S P
SP
Wang
J T
JT
Grayston
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D002689:Chlamydia / Q000276:immunology / Q000302:isolation & purification / Q000472:pathogenicity*; D002690:Chlamydia Infections / Q000097:blood / Q000276:immunology / Q000382:microbiology*; D005260:Female; D007074:Immunoglobulin G / Q000032:analysis; D007958:Leukocyte Count; D008297:Male; D009305:Nasopharynx / Q000382:microbiology; D010215:Papio / Q000382:microbiology*; D013045:Species Specificity; D014774:Virulence
D000907:Antibodies, Bacterial; D007074:Immunoglobulin G