Morphological integration in the cranium during anuran metamorphosis.
We examined the role of thyroid hormone in mediating morphological integration between cranial cartilage and bone during anuran metamorphosis. Exogenous T3 applied to premetamorphic tadpoles (Bombina orientalis) via intracranial implants of plastic micropellets precociously induced typical metamorphic changes in both tissues, but also dissociated the relative timing of developmental events between them. Morphological integration between the two primary cranial tissues is achieved in part by each tissue responding independently to endocrine factors and does not reflect a tight developmental coupling between them.
Hanken
J
J
Department of Environmental, Population, and Organismic Biology, University of Colorado, Boulder 80309-0334.
Summers
C H
CH
Hall
B K
BK
D000818:Animals; D001001:Anura / Q000254:growth & development*; D002356:Cartilage / Q000187:drug effects / Q000254:growth & development; D007814:Larva / Q000254:growth & development; D008675:Metamorphosis, Biological; D012886:Skull / Q000033:anatomy & histology / Q000187:drug effects / Q000254:growth & development*; D014284:Triiodothyronine / Q000494:pharmacology
D014284:Triiodothyronine