Is danazol a useful treatment in unexplained primary infertility?
39 patients with primary unexplained infertility were treated in a double-blind placebo-controlled study of danazol. 14 patients completed a treatment course of danazol and 17 of placebo. One patient in the placebo group conceived during the 12 months follow-up period, and none in the danazol group. Danazol does not seem to be an effective treatment for unexplained primary infertility.
Academic Department of Obstetrics and Gynaecology, Royal Free Hospital, London.
C A
CA
Iffland
R W
RW
Shaw
J L
JL
Beynon
D000328:Adult; D003613:Danazol / Q000009:adverse effects / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy*; D011245:Pregnadienes / Q000627:therapeutic use*; D011379:Prognosis; D011897:Random Allocation
D011245:Pregnadienes; D003613:Danazol