A case of pre-leukaemia masquerading as haemolytic anaemia due to multi-enzymopathy of the red cell.
A 19 year old woman presented as a case of haemolytic anaemia due to multi-enzyme deficiency of the erythrocyte. After a transient improvement with folic acid therapy, she developed acute myeloblastic leukaemia. This is the second reported case of a myelodysplastic syndrome presenting with a haemolytic picture and subsequently developing an acute myeloblastic leukaemia.
Balasubramanian
R
R
Aroor
A R
AR
Gopalakrishnan
K
K
Shenoy
U D
UD
Rao
A V
AV
Rao
B K
BK
D000328:Adult; D000743:Anemia, Hemolytic / Q000175:diagnosis* / Q000209:etiology*; D003937:Diagnosis, Differential; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000150:complications; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000209:etiology; D011289:Preleukemia / Q000175:diagnosis*; D011770:Pyruvate Kinase / Q000172:deficiency
D011770:Pyruvate Kinase