Ultrastructure of penetrating Giardia trophozoite and the possible mechanism of invasion.
The ultrastructure of penetrating Giardia lamblia trophozoites in immunosuppressed albino rats is described for the first time. Recorded changes in the general contour of the parasite; loss of flagellae, and suction disc, disappearance of the endoplasmic reticulum, appearance of abundant electron dense coarse granules as well as large sized vacuoles opening to outside, are probably modifications associated with penetration and accommodation to the new environment. Penetration appears to be due to activity of the trophozoite rather than passive transfer by tissue macrophages.
S A
SA
Salem
M E
ME
Azab
S A
SA
Soffar
S A
SA
Bishara
A A
AA
el Kadery
D000818:Animals; D005872:Giardia / Q000472:pathogenicity / Q000648:ultrastructure*; D005873:Giardiasis / Q000276:immunology / Q000469:parasitology*; D007165:Immunosuppression Therapy; D051381:Rats