Prediction of recurrence in the treatment of Dupuytren's disease: evaluation of a histologic classification.
Histologic staging of Dupuytren's lesions into three types is proposed: a proliferative type with high cellularity and mitosis, a fibrocellular type characterized by the presence of a reticulin network, and a fibrous type with few cells. Sixty-three patients (77 hands) who had selective fasciectomy as a primary procedure and whose histologic specimen was available were clinically reviewed for disease recurrence and extension. Twenty-two hands (29%) were free of disease; twenty-five (32%) were free from recurrence but showed an extension, and thirty (39%) had a recurrence. This histologic classification seems to have a prognostic value because the recurrence rate is higher in type I (70%) and lower in type III (18%). The risk of extension did not correlate with the histologic type.
Rombouts
J J
JJ
Department of Surgery, Saint-Luc University Hospital, Brussels, Belgium.
Noël
H
H
Legrain
Y
Y
Munting
E
E
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004387:Dupuytren Contracture / Q000473:pathology* / Q000601:surgery; D000071938:Fasciotomy; D005260:Female; D006225:Hand / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012008:Recurrence; D012189:Retrospective Studies