Seroepidemiologic survey for antibodies to human retroviruses in human and non-human primates in Brazil.
The prevalence of antibodies to HTLV-I and HIV-I in Brazil was determined by testing sera from: (a) 119 members of an isolated Amazonian community of African origin; (b) 100 voluntary blood donors in Rio de Janeiro; (c) 215 patients treated at the Hematology Service, National Cancer Institute, Rio de Janeiro, and (d) 44 Cebus apella New World monkeys, wild-caught in Amazonia. Anti-HTLV-I was detected in 1 (0.84%) of 119 Amazonians, in 8 (3.72%) of the 215 patients and in none of the blood donors or monkeys. The high prevalence found in patients included 4 (5.79%) of 69 with non-Hodgkin lymphoma, 2 (5.88%) of 34 with Hodgkin lymphoma, 1 (16.66%) of 6 patients with diagnosis of anemia and 1 (20%) of 5 with HIV-I infection. Anti-HIV-I was found in 7 (14.89%) of 47 patients and in none of the other groups. The high incidence of HTLV-I infection in the patient group suggests that this retrovirus is endemic in parts of Brazil.
Basic Research Center, National Cancer Institute, Rio de Janeiro, Brazil.
M J
MJ
Andrada-Serpa
J
J
Tosswill
D
D
Schor
D
D
Linhares
J
J
Dobbin
M S
MS
Pereira
D000328:Adult; D000368:Aged; D000818:Animals; D001782:Blood Donors; D001938:Brazil; D002428:Cebus; D002648:Child; D002675:Child, Preschool; D005260:Female; D015483:HIV Antibodies / Q000032:analysis*; D015481:HTLV-I Antibodies / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged
D015483:HIV Antibodies; D015481:HTLV-I Antibodies