Acute pancreatitis in a patient treated for alcoholic hepatitis. The hypothesis of supranormal ecbolic stimulation of the pancreon.
A 33-yr-old white woman treated for alcoholic hepatitis developed acute pancreatitis during her hospital stay. At autopsy, two major pathological processes were found: alcoholic cirrhosis and chronic pancreatitis. In both, there was evidence of an acute episode, i.e., acute alcoholic hepatitis and acute hemorrhagic pancreatitis superimposed on the chronic alcoholic lesions. The sequence of events would indicate that the acute pancreatic pathology was precipitated by supranormal ecbolic stimulation of the acinar segment of the "pancreon" units, triggered as a result of a high protein and fat diet.
Tiscornia-Wasserman
P G
PG
Department of Pathology, Mount Sinai School of Medicine, CUNY, NY.
Tiscornia
O M
OM
Rybak
B J
BJ
Dreiling
D A
DA
D000208:Acute Disease; D000328:Adult; D002908:Chronic Disease; D005260:Female; D006519:Hepatitis, Alcoholic / Q000150:complications* / Q000473:pathology; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000473:pathology; D010195:Pancreatitis / Q000209:etiology* / Q000473:pathology