Potassium concentration influences the gating of K+ channels from sarcoplasmic reticulum.
Gating of K+ channels from the sarcoplasmic reticulum (SR) is influenced by the K+ concentration in the bathing solution. The probability of finding the channel open (Po) increases nonlinearly with the K+ concentration. The current two-state model which considers only voltage-dependent rate constants for the SR K+ channel should be reconsidered in the light of the present results.
Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Brasil.
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Campos-de-Carvalho
D007700:Kinetics; D008567:Membranes, Artificial; D011188:Potassium / Q000378:metabolism*; D015221:Potassium Channels / Q000378:metabolism*; D012519:Sarcoplasmic Reticulum / Q000378:metabolism*
D008567:Membranes, Artificial; D015221:Potassium Channels; D011188:Potassium