Heterotopic gastric mucosa in the duodenal bulb: relationship to peptic ulcer.
Heterotopic gastric mucosa in the duodenal bulb causes a characteristic radiologic abnormality consisting of multiple small, well-defined nodules in the mucosa. This finding was identified in 92 (5%) of 1873 consecutive standard biphasic barium examinations of the upper gastrointestinal tract. Of these 92, only one patient (1%) had an associated duodenal ulcer as compared with the other 1781 patients without heterotopic gastric mucosa of whom 225 (13%) had duodenal ulcers or scars (p = .002). No gastric ulcers or ulcer scars were identified in the patients with heterotopic gastric mucosa, whereas ulcers or scars were identified in 88 patients (5%) without heterotopic gastric mucosa (p = .05). These data raise the possibility that heterotopic gastric mucosa protects against peptic ulceration.
Department of Radiology, St. Elisabeth's of Groote Gasthuis, the Netherlands.
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D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002828:Choristoma / Q000150:complications* / Q000000981:diagnostic imaging; D004379:Duodenal Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging; D004381:Duodenal Ulcer / Q000209:etiology*; D005753:Gastric Mucosa; D006801:Humans; D008875:Middle Aged; D011859:Radiography; D013276:Stomach Ulcer / Q000209:etiology*