Effect of prostaglandin F2 alpha on adrenal-produced steroid hormones in cows.
Ovariectomized, nonlactating cows were treated with IM injections of either physiologic saline solution or prostaglandin F2 alpha. Plasma concentrations of cortisol increased significantly by 30 to 60 minutes after injection of prostaglandin F2 alpha, but there were no significant increases in plasma concentrations of estradiol, progesterone, or testosterone. After saline solution treatment, there were no increases in any of the hormones measured.
Section of Reproductive Studies, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA 19348.
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Watson
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Hinrichs
D000311:Adrenal Glands / Q000187:drug effects* / Q000378:metabolism; D000818:Animals; D002417:Cattle / Q000378:metabolism*; D015237:Dinoprost / Q000494:pharmacology*; D004958:Estradiol / Q000096:biosynthesis / Q000097:blood; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006854:Hydrocortisone / Q000096:biosynthesis / Q000097:blood*; D011374:Progesterone / Q000096:biosynthesis / Q000097:blood; D013739:Testosterone / Q000096:biosynthesis / Q000097:blood; D013997:Time Factors
D012739:Gonadal Steroid Hormones; D013739:Testosterone; D011374:Progesterone; D004958:Estradiol; D015237:Dinoprost; D006854:Hydrocortisone