Functions of the corpus callosum: observations from callosotomy performed for intractable epilepsy.
The effects of complete and partial corpus callosotomy in 6 patients are reported. Only the 2 cases undergoing total callosotomy showed evidence of impaired interhemispheric sensory transfer, related to sectioning of the splenium. Only mild long-lasting neuropsychological deficits were detected. Post-commissurotomy mutism and akinesia appeared in 4 cases, 2 with total, and 2 with partial anterior callosotomy. The short-and long-term effects of corpus callosotomy appear to be related to the extent of the section the creation of lesions during the surgical procedure, and a peculiar organization of cognitive functions in chronic epileptic patients.
B
B
Censori
M
M
Del Pesce
L
L
Provinciali
A
A
Quattrini
S
S
Mancini
I
I
Papo
D000328:Adult; D000405:Akinetic Mutism / Q000209:etiology* / Q000503:physiopathology; D003337:Corpus Callosum / Q000503:physiopathology / Q000601:surgery*; D004827:Epilepsy / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008722:Methods; D009155:Mutism / Q000209:etiology* / Q000503:physiopathology; D011184:Postoperative Period; D011379:Prognosis