Neurophysiological evidence of auditory channel anomalies in developmental dysphasia.
Steady-state auditory evoked responses to frequency-modulated tones were obtained from normal children and two groups of children with developmental language disorders (developmental dysphasia). Children with predominantly expressive language impairment produced responses not different from normal children, while children with primary receptive language impairment produced responses that were markedly diminished, even absent. This occurred in recordings from either cerebral hemisphere and at mean frequency-modulation depths ranging from +/- 20 to +/- 100 Hz. Pathophysiology of auditory mechanisms concerned with frequency-modulation analysis are particularly associated with receptive developmental language impairment and may underlie associated difficulties in speech perception.
University Department of Clinical Neurology, Radcliffe Infirmary, Oxford, England.
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Stefanatos
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Green
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Ratcliff
D000161:Acoustic Stimulation; D000293:Adolescent; D001921:Brain / Q000503:physiopathology*; D002648:Child; D004423:Ear / Q000002:abnormalities*; D005072:Evoked Potentials, Auditory; D006801:Humans; D007805:Language Development Disorders / Q000209:etiology / Q000503:physiopathology* / Q000523:psychology; D012016:Reference Values; D013067:Speech Perception