[The role of hyperbaric oxygenation in the complex treatment of patients with type 1 diabetes mellitus].
The results of management of decompensated type I diabetes patients were evaluated. The first group (152 patients), in addition to the traditional therapy (diet No. 9, insulin), underwent hyperbaric oxygenation (10-15 sessions, 60 min exposure at 1.7 ATA). The second group (137 patients) underwent traditional therapy. The treatments' efficacy was compared according to the indices of the hormonal status, blood gas, cell metabolism, oxygen transport function of erythrocytes, and microcirculation status. The application of HBO in the complex management of severe DM allowed for early (12-19th day) compensation of carbohydrate metabolism, reduction of anti-insulin hormone level and of the total secretory activity of the sympathoadrenal system, stimulation of the residual pancreatic beta-cell function, and insulin dose reduction. HBO facilitated normalization of blood gas content, improvement of cell metabolism, oxygen transport, and microcirculation status. The traditional therapy resulted in less pronounced (or absent) positive changes in these indices which were manifest on the 25-27th day of treatment.
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Kakhnovskiĭ
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D000328:Adult; D003131:Combined Modality Therapy; D003922:Diabetes Mellitus, Type 1 / Q000628:therapy*; D005260:Female; D006801:Humans; D006931:Hyperbaric Oxygenation; D008297:Male
Rol' giperbaricheskoĭ oksigenatsii v kompleksnom lechenii bol'nykh sakharnym diabetom 1 tipa.