Pressure drop and flow rate measurements in a human aortic bifurcation cast for steady and pulsatile flow.
Pressure drop and flow rate measurements in a rigid cast of a human aortic bifurcation under both steady and physiological pulsatile flow conditions are reported. Integral momentum and mechanical energy balances are used to calculate impedance, spatially averaged wall shear stress and viscous dissipation rate from the data. In the daughter branches, steady flow impedance is within 30% of the Poiseuille flow prediction, while pulsatile flow impedance is within a factor of 2 of fully developed, oscillatory, straight tube flow theory (Womersley theory). Estimates of wall shear stress are in accord with measurements obtained from velocity profiles. Mean pressure drop and viscous dissipation rate are elevated in pulsatile flow relative to steady flow at the mean flow rate, and the exponents of their Reynolds number dependence are in accord with available theory.
Klanchar
M
M
Department of Chemical Engineering, Pennsylvania State University, University Park 16802.
Tarbell
J M
JM
D000368:Aged; D001011:Aorta / Q000502:physiology*; D001696:Biomechanical Phenomena; D001794:Blood Pressure; D005260:Female; D006801:Humans; D008955:Models, Cardiovascular; D011673:Pulsatile Flow; D012212:Rheology; D013314:Stress, Mechanical; D014655:Vascular Resistance