Pizotifen in deafferentation pain.
Deafferentation pain is known usually to be resistant to both narcotic and non-narcotic analgesics. Four cases of this condition are reported here in which benefit was obtained with pizotifen, a 5-hydroxytryptamine antagonist. Further controlled clinical studies are required to verify this observation.
University Department of Geriatric Medicine, Cardiff Royal Infirmary, UK.
K
K
Ghose
D000344:Afferent Pathways; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006429:Hemiplegia / Q000503:physiopathology; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000503:physiopathology*; D008297:Male; D009069:Movement Disorders / Q000503:physiopathology; D010146:Pain / Q000188:drug therapy*; D010918:Pizotyline / Q000627:therapeutic use*; D013577:Syndrome; D013786:Thalamic Diseases / Q000503:physiopathology*; D013876:Thiophenes / Q000627:therapeutic use*
D013876:Thiophenes; D010918:Pizotyline