pH regulation of calcium efflux by turtle liver mitochondria.
1. Turtle liver mitochondria are capable of taking up calcium in a pattern similar to that described from rat liver mitochondria. 2. Turtle liver mitochondria also possess a system for calcium efflux which is extremely sensitive to changes in extramitochondrial pH. A decrease in extramitochondrial pH by addition of HCl or by gassing with CO2 caused a rapid release of calcium. 3. The profound changes in pH and pCO2 during deep diving likely affects Ca efflux from mitochondria in the turtle liver.
Arruda
J A
JA
Section of Nephrology, University of Illinois College of Medicine, Chicago 60612.
Dytko
G
G
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D006706:Homeostasis; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D014426:Turtles / Q000378:metabolism*
D002118:Calcium