[Effect of irradiation on the cellular sensitivity of separate NKLy tumor subpopulations to the membrane-toxic action of natural killers].
A study was made of sensitivity of NKLy tumor fractions, differing in the proliferative activity, position in the cell cycle, and ploidy, to membrane-toxic action of natural killer cells from mouse spleen. The membrane toxicity index for cells of three out of five fractions under study was shown to decrease after exposure to 4 Gy radiation. It is concluded that there is no correlation between NKLy cell sensitivity to membrane-toxic effect of natural killer cells and their radiosensitivity as well as their ability to repair potentially lethal damages.
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D000818:Animals; D002462:Cell Membrane / Q000276:immunology / Q000528:radiation effects; D003602:Cytotoxicity, Immunologic / Q000528:radiation effects*; D007694:Killer Cells, Natural / Q000276:immunology / Q000528:radiation effects*; D008228:Lymphoma, Non-Hodgkin / Q000276:immunology* / Q000532:radiotherapy; D051379:Mice; D011836:Radiation Tolerance; D013154:Spleen / Q000276:immunology / Q000528:radiation effects
Vliianie oblucheniia na chuvstvitel'nost' kletok iz otdel'nykh subpopuliatsiĭ opukholi NKLy k membranotoksicheskomu deĭstviiu estestvennykh killerov.