Estrogen-induced vitellogenin production by triploid coho salmon (Oncorhynchus kisutch), and its effect on plasma and pituitary gonadotropin.
Vitellogenin production was induced in immature diploid and triploid coho salmon by the weekly injection of 17 beta-estradiol at 1 mg/kg body wt. There was no significant difference between diploids and triploids for any of the results obtained, i.e., change in plasma vitellogenin and gonadotropin levels, hepatosomatic index, or pituitary gonadotropin content. Plasma vitellogenin levels were significantly higher in 17 beta-estradiol-treated fish than in sham-injected fish within a week of the first injection, and continued to rise with each subsequent injection. Plasma gonadotropin levels, on the other hand, were slightly (but significantly) depressed. The 17 beta-estradiol-treated fish had higher hepatosomatic indices and pituitary gonadotropin contents than sham-injected fish by 3 weeks after the first treatment. These data suggest that the occasional postmeiotic oocytes observed in triploids do not grow to full maturity due, in part, to an absent or diminished estrogen stimulus from the ovary on hepatic vitellogenin production.
Benfey
T J
TJ
Department of Fisheries and Oceans, West Vancouver Laboratory, British Columbia, Canada.
Dye
H M
HM
Donaldson
E M
EM
D000818:Animals; D004967:Estrogens / Q000494:pharmacology*; D005260:Female; D006062:Gonadotropins / Q000097:blood*; D006065:Gonadotropins, Pituitary / Q000378:metabolism*; D008297:Male; D010902:Pituitary Gland / Q000187:drug effects; D011003:Ploidies; D012474:Salmon / Q000502:physiology*; D014818:Vitellogenesis / Q000187:drug effects*; D014819:Vitellogenins / Q000378:metabolism / Q000494:pharmacology*
D004967:Estrogens; D006062:Gonadotropins; D006065:Gonadotropins, Pituitary; D014819:Vitellogenins