Surface modification of copolyether-urethane catheters with poly(ethylene oxide).
Pellethane 2363 80A catheters were modified with poly(ethylene oxide) in order to improve their blood compatibility. Contact angle measurements showed that Pellethane 2363 80A surfaces had increased wettability after this modification. The results of in vitro blood compatibility tests showed that surface modification with poly(ethylene oxide) resulted in a five-fold reduction of platelet deposition. Activation of coagulation was not affected.
Brinkman
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E
Department of Chemical Technology, Twente University of Technology, Department of Chemical Technology, Twente University of Technology, Enschede, The Netherlands.
Poot
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A
Beugeling
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T
van der Does
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L
Bantjes
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A
D001672:Biocompatible Materials; D001790:Blood Physiological Phenomena; D002404:Catheterization; D004867:Equipment Design; D066298:In Vitro Techniques; D011092:Polyethylene Glycols; D011140:Polyurethanes
D001672:Biocompatible Materials; D011140:Polyurethanes; C059617:pellethane 2363-55D; D011092:Polyethylene Glycols