Usefulness of twenty-four-hour blood pressure patterns and response to short-term sodium restriction in normotensive subjects in detecting a predisposition to systemic arterial hypertension.
Twenty clinically healthy subjects were studied to identify normotensive adults with a predisposition to arterial hypertension by monitoring blood pressure (BP) and restricting dietary sodium intake. Short-term restriction in sodium intake resulted in a decrease of the mean level for the circadian rhythm of BP. The phenomenon is visible in subjects without familial hypertension but not in individuals with a positive history for high BP. The response of the 24-hour BP patterns to abrupt sodium deprivation seems to be an indicator for discovering normotensive subjects at risk of developing arterial hypertension.
Endocrine Pathophysiology (Chronobiology) Unit, University of Rome, Italy.
P
P
Cugini
D
D
Danese
P
P
Battisti
L
L
Di Palma
G
G
Leone
T
T
Kawasaki
D000328:Adult; D001794:Blood Pressure; D001795:Blood Pressure Determination / Q000379:methods; D002940:Circadian Rhythm; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis*; D008297:Male; D008991:Monitoring, Physiologic; D012307:Risk Factors; D012982:Sodium, Dietary / Q000008:administration & dosage*
D012982:Sodium, Dietary