Familial ovarian cancer: a study of 11 families.
In a group of 152 ovarian cancer patients, 11 cases with familial recurrence were investigated (7.23%). Of the families evaluated we found 26 patients with ovarian cancer and twenty two with different cancers in other sites. In ovarian cancer the familial aspect, despite its relatively low frequency, is one of the few factors for identifying "high risk" patients, thus allowing effective secondary prevention.
Gynec. Oncol. Service, State University La Sapienza, Rome, Italy.
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Villani
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Ficorella
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Tomao
D000328:Adult; D000368:Aged; D005192:Family Health; D005260:Female; D006801:Humans; D007558:Italy; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000453:epidemiology / Q000235:genetics*; D012307:Risk Factors