Cerebral sarcoidosis presenting as supranuclear gaze palsy with hypokinetic rigid syndrome.
A 31-year-old man with histologically documented pulmonary sarcoidosis developed a severe hypokinetic rigid syndrome with a supranuclear gaze palsy following recurrent lymphocytic meningitis and occlusive hydrocephalus. Magnetic resonance imaging (MRI) showed multiple hyperintense foci in the CNS, not detectable by computed tomography (CT). Long-term steroid therapy led to clinical complete remission.
Department of Neurology, University Hospital of Bonn, Federal Republic of Germany.
U
U
Schlegel
P
P
Clarenbach
A
A
Cordt
A
A
Steudel
D000293:Adolescent; D001927:Brain Diseases / Q000175:diagnosis*; D006801:Humans; D008297:Male; D009068:Movement; D009127:Muscle Rigidity / Q000175:diagnosis*; D009886:Ophthalmoplegia / Q000175:diagnosis*; D012507:Sarcoidosis / Q000175:diagnosis*; D013577:Syndrome