New antitumor antibiotics, duocarmycins B1 and B2.
Pharmaceutical Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Shizuoka, Japan.
T
T
Ogawa
M
M
Ichimura
S
S
Katsumata
M
M
Morimoto
K
K
Takahashi
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000096:biosynthesis / Q000302:isolation & purification*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D000080890:Duocarmycins; D005285:Fermentation; D007211:Indoles; D051379:Mice; D011760:Pyrrolidinones / Q000096:biosynthesis / Q000302:isolation & purification / Q000494:pharmacology; D013302:Streptomyces / Q000378:metabolism
D000903:Antibiotics, Antineoplastic; D000080890:Duocarmycins; D007211:Indoles; D011760:Pyrrolidinones; C060648:duocarmycin B1; C060649:duocarmycin B2