[Angina pectoris caused by dynamic coronary obstruction and beta-blockers].
This review of the literature covers the clinical results of treatment with beta-blockers in those forms of cardiac ischaemia characterised by a coronary vasomotor component. Particular consideration is given to a paper by Mulcahy et al. which confirms and reinforces the results of other clinical works on the therapeutic effectiveness of the cardioselective beta-blocker atenolol in these mixed forms of ischaemia (fixed coronary stenosis plus dynamic coronary stenosis). The effectiveness of atenolol proved greater or at least on a par with that of the calcium antagonist nifedipine. The probable mechanisms underlying these clinical results are described and it is concluded by noting the therapeutic potentiation obtainable using the beta-blocker together with nifedipine.
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G
Pinelli
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Di Pasquale
D000787:Angina Pectoris / Q000188:drug therapy*; D001262:Atenolol / Q000627:therapeutic use*; D006801:Humans; D009543:Nifedipine / Q000627:therapeutic use*
D001262:Atenolol; D009543:Nifedipine
Angina pectoris da ostruzione coronarica dinamica e beta bloccanti.