[Creatine kinase BB and lactate in the cerebrospinal fluid of neonates and infants with perinatal injuries of the CNS].
A study was made of the content of creatine kinase-BB (CK-BB) and lactate in cerebrospinal fluid (CSF) of 202 neonates and infants with perinatal CNS injuries. The relationship was found between the rise of the CK-BB content and the gravity of perinatal CNS injuries. The highest content of CK-BB in CSF was marked in neonates with cerebral disorders complicated by infectious and inflammatory diseases (pneumonia, sepsis). Within the first 5 days of life, the children of this group demonstrated the relationship between the content of CK-BB and lactate of CSF. The measurement of the content of CK-BB in CSF should be used for early diagnosis, assessment of the gravity and course of perinatal CNS injuries in neonates and in infants.
Alatyrtsev
V V
VV
Iakunin
Iu A
IuA
Burkova
A S
AS
Podkopaev
V N
VN
Afonina
L G
LG
D000367:Age Factors; D001720:Birth Injuries / Q000134:cerebrospinal fluid* / Q000175:diagnosis; D002490:Central Nervous System / Q000293:injuries*; D004796:Clinical Enzyme Tests; D003402:Creatine Kinase / Q000134:cerebrospinal fluid*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007527:Isoenzymes; D007773:Lactates / Q000134:cerebrospinal fluid*
D007527:Isoenzymes; D007773:Lactates; D003402:Creatine Kinase
Kreatinkinaza-BB i laktat v spinnomozgovoĭ zhidkosti u novorozhdennyki u deteĭ rannego vozrasta s perinatal'nymi porazheniiami TsNS.