[Distribution of the antigen of hepatitis B virus in liver tissue in healthy carriers and in patients with chronic active and acute hepatitis].
We have studied 120 cases of B hepatitis. Sixty were healthy carriers of B virus, 40 had chronic active hepatitis (CAH) and 20 acute hepatitis (AH). The AgsHBV distribution was made in liver tissue by immunoperoxidase technic. In 73% of patients with CAH the AgsHBV was found around portal tracts. In contrast in patients with AH the AgsHBV was seen around central vein. Healthy carriers showed an disseminated pattern. All healthy carrier had AgSHBV in liver, in contrast only 65% of patients with CAH and 20% with AH exhibited AgSHBV in liver biopsy.
Garciá-Ruiz
H
H
Sotto-Escobar
A
A
Gra-Oramas
B
B
D000208:Acute Disease; D000328:Adult; D002353:Carrier State / Q000276:immunology*; D005260:Female; D006509:Hepatitis B / Q000276:immunology*; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006521:Hepatitis, Chronic / Q000276:immunology*; D006801:Humans; D008099:Liver / Q000276:immunology*; D008297:Male
D006514:Hepatitis B Surface Antigens
Distribución del antígeno del virus de la hepatitis B en tejido hepático, en portadores sanos y en pacientes con hepatitis crónica activa y aguda.