[Binding of monoclonal antibodies to fragmented erythrocyte membranes in patients with arterial hypertension].
The data obtained by radioimmunoassay indicate that monoclonal antibodies (MA) to sarcoplasmic reticulum membranes can also bind to erythrocyte membranes. The binding of MA to fragmented erythrocyte membranes from patients with essential hypertension (n = 20) is 35% higher, as compared to normal subjects (n = 14) or patients with secondary (renal) hypertension (n = 9). Possible use of radioimmunoassays for MA is discussed with reference to differential diagnosis of arterial hypertensions.
V A
VA
Loginov
D O
DO
Levitskiĭ
S A
SA
Sukhoplechev
B I
BI
Minchenko
A A
AA
Aleksandrov
D000328:Adult; D000911:Antibodies, Monoclonal / Q000276:immunology*; D001665:Binding Sites; D004910:Erythrocyte Membrane / Q000276:immunology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000276:immunology; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged
D000911:Antibodies, Monoclonal
Sviazyvanie monoklonal'nykh antitel s fragmentirovannymi membranami éritrotsitov bol'nykh s arterial'nymi gipertenziiami.