[Neurocutaneous melanosis].
The authors report on a patient of 33 years of age suffering from neurocutaneous melanosis in whom two years after excision of a naevus pigmentosus et pilosus giganteus cellular proliferation of the melanoblasts in the area of the soft meninges was seen. This process led to the death of the patient within a few weeks' time despite intensive therapeutic measures, the manifestation being that of a generalised space-occupying growth in the CNS. Neuroradiological techniques can objectify the clinical pattern of signs of this very rare disease and may possibly enable an early diagnosis.
Husstedt
I W
IW
Klinik und Poliklinik für Neurologie der Westf. Wilhelmsuniversität Münster.
Grotemeyer
K H
KH
Galanski
M
M
Schlake
H P
HP
D000328:Adult; D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis*; D008577:Meningeal Neoplasms / Q000175:diagnosis*; D008578:Meninges / Q000473:pathology; D009192:Myelography; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D009508:Nevus, Pigmented / Q000175:diagnosis*; D012878:Skin Neoplasms / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed
Zur neurokutanen Melanose.