Alport's syndrome and the eye.
Alport's syndrome comprises hereditary deafness, nephritis and ocular abnormalities. The features of Alport's syndrome are illustrated by a family with Alport's syndrome and hereditary oesophageal leiomyomatosis. The evidence that Alport's syndrome is due to a widespread basement membrane disorder is noted. Treatment of anterior lenticonus, the principal ocular abnormality, by lensectomy and intraocular lens insertion is recommended.
McCartney
P J
PJ
Department of Ophthalmology, Prince of Wales Hospital, New South Wales.
McGuinness
R
R
D000328:Adult; D004938:Esophageal Neoplasms / Q000151:congenital*; D006801:Humans; D007889:Leiomyoma / Q000151:congenital*; D007908:Lens, Crystalline / Q000002:abnormalities* / Q000601:surgery; D007910:Lenses, Intraocular; D008297:Male; D009394:Nephritis, Hereditary / Q000235:genetics / Q000473:pathology*