Centrosome movement in the early divisions of Caenorhabditis elegans: a cortical site determining centrosome position.
In Caenorhabditis elegans embryos, early blastomeres of the P cell lineage divide successively on the same axis. This axis is a consequence of the specific rotational movement of the pair of centrosomes and nucleus (Hyman, A. A., and J. G. White. 1987. J. Cell Biol. 105:2123-2135). A laser has been used to perturb the centrosome movements that determine the pattern of early embryonic divisions. The results support a previously proposed model in which a centrosome rotates towards its correct position by shortening of connections, possibly microtubules, between a centrosome and a defined site on the cortex of the embryo.
Hyman
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Laboratory of Molecular Biology, Medical Research Council, Cambridge, England.
D000818:Animals; D001757:Blastomeres / Q000166:cytology* / Q000528:radiation effects / Q000648:ultrastructure; D002107:Caenorhabditis / Q000196:embryology*; D002455:Cell Division / Q000528:radiation effects; D004625:Embryo, Nonmammalian / Q000166:cytology; D007834:Lasers; D008870:Microtubules / Q000528:radiation effects / Q000648:ultrastructure*; D008938:Mitosis / Q000528:radiation effects