Severity of withdrawal in subjects exposed to a combination of alcohol and minor tranquillisers.
Fifty patients suffering from the alcohol dependence syndrome were detoxified over a 10-day period using a reducing regime of chlordiazepoxide. Twenty-four had been consuming minor tranquillisers together with alcohol prior to admission. The severity of the withdrawal syndrome was assessed daily but no differences were found between the 26 who had taken alcohol alone and the 24 who had taken a combination of alcohol and drugs. Four from each group had a transient hallucinosis and none had fits.
Alcohol Treatment Unit, University Hospital of South Manchester.
C S
CS
Thomas
M
M
Spurrell
R D
RD
Hackett
B D
BD
Hore
D000328:Adult; D000437:Alcoholism / Q000188:drug therapy*; D001569:Benzodiazepines / Q000009:adverse effects*; D002719:Chlormethiazole / Q000009:adverse effects*; D005260:Female; D006212:Hallucinations / Q000139:chemically induced; D006801:Humans; D008297:Male; D008875:Middle Aged; D013375:Substance Withdrawal Syndrome; D013997:Time Factors
D002719:Chlormethiazole; D001569:Benzodiazepines