[Follow-up of cases of diabetes mellitus existing over 25 years].
The life prospects of patients grew parallel with the improving possibilities of the treatment of diabetes mellitus. In 36 insulin-treated patients with diabetes existing longer than 25 years, obesity, smoking and alcohol consumption were infrequent, microangiopathic complications were moderate and displayed protracted course. Lability of carbon hydrate metabolism does not characterize the long lasting diabetes. Higher insulin requirement was found only with patients whose sulphonylurea resistance made later necessary the insulin therapy. Organic manifestations of macroangiopathy, hypertension and hypercholesterinemia were often observed. Two patients remained free of complications even after 28- and 31 years long diabetes. Long-term insulin dependent or after oral administration insulin treated diabetes mellitus continuing even in old age is a relatively benign slowly progressing disease.
Holländer
E
E
D003920:Diabetes Mellitus; D003922:Diabetes Mellitus, Type 1 / Q000401:mortality / Q000503:physiopathology*; D003925:Diabetic Angiopathies / Q000401:mortality; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006814:Hungary; D006973:Hypertension / Q000150:complications; D008297:Male; D009765:Obesity; D013997:Time Factors
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