[The effect of radiotherapy on the antioxidative activity of tissues and blood erythrocytes].
Dynamics of antioxidative activity (AOA) of lipids was studied in tumors, in the tissues surrounding tumor and in blood plasma and erythrocytes of patients with mammary gland carcinoma after surgical and combined treatments. Intensity of lipid peroxidation was increased in blood plasma and erythrocytes of the treated patients within the later periods of the disease. AOA of the tumor lipids was elevated after the radiation treatment; at the same time, similar reaction to radiotherapy was detected in erythrocytes and the tissues surrounding tumor: a decrease in the AOA within the initial steps and elevation--during the later periods of the disease as compared with the activity in erythrocytes and tissues of treated patients. Qualitatively altered conditions of body functioning and its relationship with the tumor occurred apparently during the later periods of the disease.
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Kal'nova
D001940:Breast / Q000528:radiation effects; D001943:Breast Neoplasms / Q000378:metabolism / Q000532:radiotherapy* / Q000601:surgery; D003131:Combined Modality Therapy; D004912:Erythrocytes / Q000378:metabolism / Q000528:radiation effects*; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation / Q000528:radiation effects*; D008099:Liver / Q000378:metabolism / Q000528:radiation effects; D010084:Oxidation-Reduction; D013154:Spleen / Q000378:metabolism / Q000528:radiation effects
Vliianie radioterapii na antiokislitel'nuiu aktivnost' tkaneĭ i éritrotsitov krovi.