Ultrasonic assessment of the endometrium as a predictor of oestrogen status in amenorrhoeic patients.
Thirty consecutive amenorrhoeic patients were assessed with regard to the following: medical history, physical examination, pelvic ultrasonography, serum levels of 17-beta oestradiol (E2), other relevant serum hormones and the response to a progesterone challenge test. The results showed a correlation coefficient of 71% (P = 0.001) between the E2 levels and the endometrial width and of 52% (P = 0.03) between the testosterone levels and the E2 levels. Linear regression of endometrial width against E2 levels showed beta = 0.018 (R2 = 22%, P = 0.02). Patients with an endometrial width of 4 mm or less reported no bleeding or only scanty bleeding following progesterone and all the patients with an endometrial width of greater than 5 mm responded to progesterone with normal menstrual bleeding.
Shulman
A
A
Department of Obstetrics and Gynaecology B, Meir Hospital, Tel Aviv University, Kfar Saba, Israel.
Shulman
N
N
Weissenglass
L
L
Bahary
C
C
D000293:Adolescent; D000328:Adult; D000568:Amenorrhea / Q000097:blood / Q000209:etiology / Q000473:pathology*; D004717:Endometrium / Q000187:drug effects / Q000473:pathology*; D004958:Estradiol / Q000097:blood*; D005260:Female; D006801:Humans; D008525:Medroxyprogesterone / Q000494:pharmacology; D013739:Testosterone / Q000097:blood*; D014465:Ultrasonics
D013739:Testosterone; D004958:Estradiol; D008525:Medroxyprogesterone