Acute aluminum encephalopathy in an uremic patient.
A patient on maintenance hemodialysis developed an acute encephalopathy closely related to a rapid increase in serum aluminum levels. Aluminum hydroxide and sucralfate had been given in large amounts for the treatment of a gastrointestinal bleeding episode. The breach of the gastrointestinal barrier to aluminum absorption, the increase in gastric pH caused by cimetidine, and the presence of gastric telangiectasia acting together in a uremic patient could have precipitated the acute aluminum encephalopathy.
Campistol
J M
JM
Nephrology Service, Hospital Clinic, Barcelona, Spain.
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D000208:Acute Disease; D000535:Aluminum / Q000097:blood; D000536:Aluminum Hydroxide / Q000009:adverse effects*; D001927:Brain Diseases / Q000139:chemically induced*; D006471:Gastrointestinal Hemorrhage / Q000150:complications / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D013392:Sucralfate / Q000009:adverse effects*; D014511:Uremia / Q000097:blood / Q000150:complications*
D013392:Sucralfate; D000536:Aluminum Hydroxide; D000535:Aluminum