Usefulness of acid and gastric juice secretion decreasing action of cimetidine in anaesthesia for the prevention of aspiration.
The effect of Histodil injection on the amount and pH of the gastric juice has been examined in women undergoing caesarean section under intratracheal anaesthesis. According to the results cimetidine decreases the volume and acidity of gastric secretion to a significantly higher extent than the pretreatment with atropine as a single agent. Maximum effect may be expected within 60-90 minutes. With Cimetidine pretreatment the risk of aspiration and pneumonitis may be prevented.
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Takács
D000328:Adult; D000773:Anesthesia, Obstetrical; D002585:Cesarean Section; D002927:Cimetidine / Q000627:therapeutic use*; D005260:Female; D005744:Gastric Acid / Q000378:metabolism*; D005750:Gastric Juice / Q000378:metabolism*; D006801:Humans; D011015:Pneumonia, Aspiration / Q000517:prevention & control*; D011229:Preanesthetic Medication; D011247:Pregnancy
D002927:Cimetidine