[Measurement of phospholipids in erythrocytes, plasma and platelets in a patient with hereditary spherocytosis].
The amount and distribution of phospholipids (PLs) were studied in erythrocytes, plasma and platelets of one patient with hereditary spherocytosis (HS). Phosphatidylethanolamine (PE) was always decreased. Total PLs amount was remarkably reduced in erythrocytes but normal in platelets. Since platelets do not contain those proteins which have been implicated in the red cell abnormalities of patients with HS, our findings reinforce the theory that a defective protein-lipid interaction causes the abnormal lipid loss in the erythrocytes of these patients.
J M
JM
César
I
I
Fernández
J L
JL
Navarro
D000328:Adult; D001792:Blood Platelets / Q000032:analysis*; D004910:Erythrocyte Membrane / Q000032:analysis / Q000648:ultrastructure; D004912:Erythrocytes / Q000032:analysis*; D005260:Female; D006801:Humans; D008563:Membrane Lipids / Q000032:analysis; D010743:Phospholipids / Q000097:blood*; D013049:Spectrin / Q000172:deficiency; D013103:Spherocytosis, Hereditary / Q000097:blood*
D008563:Membrane Lipids; D010743:Phospholipids; D013049:Spectrin
Determinación de fosfolípidos en hematíes, plasma y plaquetas en una enferma con esferocitosis hereditaria (EH).