Determination of 1,2,4-trimethylbenzene (pseudocumene) in serum of a person exposed to liquid scintillation counting solutions by GC/MS.
1,2,4-Trimethylbenzene (pseudocumene) is often used as the solvent for liquid scintillation counting solutions. In the present work, the determination of 1,2,4-trimethylbenzene in the serum of a person exposed to the solvent vapor during the handling of liquid scintillation counting cocktails is described. The identification of 1,2,4-trimethylbenzene was carried out by GC/MS. The analyte was quantified by GC with flame ionization detection. The detection limit of the method is 0.01 ppm. Two hours after exposure of a person to the solvent vapor, the concentration of 1,2,4-trimethylbenzene in her serum was found to be 0.20 ppm.
Kenndler
E
E
Institute for Analytical Chemistry, University of Vienna, Austria.
Schwer
C
C
Huber
J F
JF
D001555:Benzene Derivatives / Q000009:adverse effects / Q000097:blood*; D004781:Environmental Exposure; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D006801:Humans; D008875:Middle Aged; D012588:Scintillation Counting; D012997:Solvents
D001555:Benzene Derivatives; D012997:Solvents; C010313:pseudocumene