The role of skin testing in the use of collagen injectable materials.
The experience of 400 consecutive patients evaluated for soft tissue augmentation for a variety of contour defects is reviewed here. The first 200 patients were evaluated with only a single skin test prior to treatment, whereas the second group were skin tested twice. The rate of hypersensitivity to the first skin test was the same in both groups, 5 out of 200 (2.5%). In the 195 patients receiving treatment after a single negative skin test, 6 (3.1%) developed hypersensitivity reaction at treatment sites. In the second group, where double skin testing was employed, an additional 7 patients had a positive second skin test (3.5%). There were no allergic reactions in the 171 patients who received treatment after two negative skin tests.
Elson
M L
ML
Dermatology Center, Nashville, Tennessee 37205.
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003094:Collagen / Q000008:administration & dosage / Q000009:adverse effects; D062109:Dermatologic Surgical Procedures; D005260:Female; D005542:Forearm; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology; D007267:Injections; D008297:Male; D008875:Middle Aged; D019736:Prostheses and Implants / Q000009:adverse effects; D012882:Skin Tests / Q000379:methods*
D003094:Collagen