Dilution of blood proteins due to irrigant absorption in transurethral prostatic resection.
The serum concentrations of albumin, transferrin, IgG, IgM and sodium, the blood haemoglobin concentration (B-Hb) and the blood loss were determined for 10-min periods in the course of 16 transurethral prostatic resections in which irrigant absorption of between 0.5 and 2.8 I had been measured volumetrically. The concentrations during resection, expressed as a percentage of those recorded just before induction of anaesthesia, were: B-Hb 89.2%, S-albumin 81.0%, S-transferrin 78.4%, S-IgG 81.0%, S-IgM 80.5% and S-Na 96.5%. The blood loss was the most important predictor of the decrease in B-Hb. The dilution of serum proteins was primarily due to hydration from crystalloid fluid given intravenously and from absorbed irrigating fluid; the most specific indicator of the degree of irrigant absorption was the serum sodium level.
Department of Anaesthesiology, Huddinge University Hospital, Sweden.
R G
RG
Hahn
D000368:Aged; D001798:Blood Proteins / Q000378:metabolism*; D006488:Hemostasis, Surgical; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D011468:Prostatectomy; D007507:Therapeutic Irrigation; D014883:Water-Electrolyte Imbalance / Q000209:etiology*
D001798:Blood Proteins