Maturation of peripheral nerves in preterm infants: proprioceptive and motor nerve conductions of tibial nerve.
Premature birth induces a profound change in the environmental factors affecting nerve maturation. The proprioceptive sensory and motor nerve conduction velocities (NCV) of the posterior tibial nerve, which reflect peripheral nerve maturation, have been measured in 3 groups of newborns. Two groups of premature (PT) babies, studied when they reached the expected date of birth (group I, gestational age (GA) at birth, 28-31 weeks, n = 8; group II, GA at birth, 32-35 weeks, n = 6) were compared to 9 normal full-term (FT) newborns. As previously shown, the motor NCV of PT babies at a post-conceptional age close to term is similar to that of FT newborns: group I, 22.70 +/- 2.95 m/s (mean +/- SD); group II, 25.90 +/- 4.61 m/s; FT, 25.48 +/- 4.09 m/s. The proprioceptive sensory NCV was significantly lower in group I (21.59 +/- 4.39 m/s) than in group II (31.89 +/- 4.15 m/s) and FT newborns (32.22 +/- 6.56 m/s) (p less than 0.01). Such a delay in maturation could be responsible for the subtle clinical dysfunctions often observed in PT babies.
Service d'Explorations fonctionnelles neurologiques, Hôpital Ambroise Paré, Boulogne, France.
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Tranier
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Bougle
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Pottier
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Venezia
D005865:Gestational Age; D006181:H-Reflex; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000502:physiology*; D009046:Motor Neurons / Q000502:physiology*; D009431:Neural Conduction; D010525:Peripheral Nerves / Q000502:physiology*; D011434:Proprioception / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D012016:Reference Values; D012584:Sciatic Nerve / Q000502:physiology; D013979:Tibial Nerve / Q000502:physiology