[Human embryonal prealbumin-1. Chemical and immunochemical characteristics].
General chemical and immunochemical characterization of human embryonic prealbumin-1 (EPA-1) isolated from abortive blood is presented. EPA-1 was found to exist as glycosylated and non-glycosylated forms, which are immunochemically identical. Sugar moiety of the glycosylated form contains residues of fucose (3.0%), mannose (3.2%), galactose (7.8%), N-acetylglucosamine (5.4%), N-acetylgalactosamine (1.2%) and N-acetylneuraminic acid. Using methylation studies, types of bonds between the sugar residues were elucidated.
Pavlenko
A F
AF
Bulgakov
A A
AA
Belogortseva
N I
NI
Ovodov
Iu S
IuS
D000818:Animals; D000951:Antigens, Neoplasm / Q000032:analysis*; D002417:Cattle; D002849:Chromatography, Gas; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006031:Glycosylation; D006801:Humans; D006868:Hydrolysis; D007122:Immunoelectrophoresis; D011228:Prealbumin / Q000032:analysis*; D011247:Pregnancy
D000951:Antigens, Neoplasm; D011228:Prealbumin; C031192:oncofetal antigens
Embrional'nyĭ preal'bumin-1 cheloveka. Khimicheskaia i immunokhimicheskaia kharakteristika.