The therapy of verrucous carcinoma of the vulva. Observations on three cases.
Vulvar verrucous carcinoma is a distinct variant of squamous cell carcinoma, with a very low biological aggressiveness. Surgery is considered to be the elective treatment, even if there is no agreement in literature about the extent of surgical resection. Radiotherapy cannot be used in the management of this neoplasia. Sometimes this therapeutic modality induces an anaplastic transformation of the tumor, which can turn into a more aggressive malignancy. In this paper the clinical histories of 3 patients with vulvar verrucous carcinoma are discussed, in particular as regards therapy.
Gadducci
A
A
Department of Obstetrics and Gynecology, University of Pisa, Italy.
De Punzio
C
C
Facchini
V
V
Rispoli
G
G
Fioretti
P
P
D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D010789:Phototherapy; D014846:Vulvar Neoplasms / Q000601:surgery / Q000628:therapy*