Adrenal catecholamine synthesis rate changes induced by combined thermal and immobilization stress in fed and 24 hour fasted rats.
The combined stress of acute immobilization (IM) at high and low ambient temperature has been used to determine its influence on adrenal catecholamine (CA) content assassed histofluorimetrically in fed and 24 hour fasted rats. The general course of changes obtained after the arrangement of adrenal strips deriving from the adrenals of rats exposed to cold and IM stress (CIMS) at +10 degrees C to -25 degrees C during the different time fragments presented the adrenal CA depletion events followed sometimes by the adrenal CA content increase after the longer stress exposure or/and stronger CIMS and WIMS conditions. It was found that this depletion-stimulated increase of adrenal Ca synthesis rate had been accelerated in 24 h fasted rats compared to satiated ones exposed to the same stress conditions, especially after the CIMS exposure. Moreover the survival time duration at first lethal temperature (-5 degrees C and +45 degrees C) was significantly higher in fasted rats. The possible hypothalamic regulation of adrenal CA synthesis rate accordingly to the actual metabolism needs and beta-adrenoceptor sensitivity changes depending on satiety state have been discussed and the necessity of further investigations concerning the specificity of stress-induced metabolism changes in 24 h starved rats has been suggested.
Bargiel
Z
Z
Department of Animal Physiology, N. Copernicus University, Toruń.
Nowicka
H
H
D000313:Adrenal Medulla / Q000378:metabolism* / Q000473:pathology; D000818:Animals; D001831:Body Temperature; D002395:Catecholamines / Q000096:biosynthesis*; D003080:Cold Temperature; D005215:Fasting; D005260:Female; D006651:Histocytochemistry; D006358:Hot Temperature; D008297:Male; D051381:Rats; D012016:Reference Values; D012149:Restraint, Physical; D013312:Stress, Physiological / Q000378:metabolism*; D013315:Stress, Psychological / Q000378:metabolism
D002395:Catecholamines