Low brain magnesium in migraine.
Brain magnesium was measured in migraine patients and control subjects using in vivo 31-Phosphorus Nuclear Magnetic Resonance Spectroscopy. pMg and pH were calculated from the chemical shifts between Pi, PCr and ATP signals. Magnesium levels were low during a migraine attack without changes in pH. We hypothesize that low brain magnesium is an important factor in the mechanism of the migraine attack.
N M
NM
Ramadan
H
H
Halvorson
A
A
Vande-Linde
S R
SR
Levine
J A
JA
Helpern
K M
KM
Welch
D000328:Adult; D001921:Brain / Q000378:metabolism*; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008274:Magnesium / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000378:metabolism*; D010759:Phosphorus Isotopes
D010759:Phosphorus Isotopes; D008274:Magnesium