[Lermoyez syndrome. Clinical aspects and follow-up].
The clinical data and follow-up of five patients with Lermoyez syndrome are reported. Three of them presented with marked lesions of the cervical spine. Serological antibodies against nuclei and sarcolemma as well as against heart muscle and gastric cells were found. Tests of the sera against guinea pig cochlear tissue showed antinuclear antibodies in one patient and against basilar membrane structures in another. Three sera were negative despite positive heterologous finding. Therapy included infusions active on the inner ear, decompression of the saccus endolymphaticus in two cases and physiotherapy for the cervical spine. These achieved marked improvement or long term relief. The available literature supports the conclusions based on pathophysiological considerations of our results. We cannot postulate an independent immunopathogenesis for Lermoyez Syndrome, but we think that the immunological findings conform with the clinical and experimental data found in the literature.
HNO-Klinik, Universität Tübingen.
H G
HG
Kempf
K
K
Jahnke
D001323:Autoantibodies / Q000032:analysis; D002150:Caloric Tests; D002574:Cervical Vertebrae; D003051:Cochlea / Q000276:immunology; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000209:etiology; D006801:Humans; D007759:Labyrinth Diseases / Q000150:complications; D008297:Male; D008575:Meniere Disease / Q000209:etiology* / Q000628:therapy; D008875:Middle Aged; D013122:Spinal Diseases / Q000150:complications; D013577:Syndrome
D001323:Autoantibodies
Lermoyez-Syndrom. Klinik und Verlauf.