Vasopressin inhibition via combined head-out water immersion and a prostaglandin E-1 precursor in the treatment of male reproductive failure due to chronic alcohol abuse.
Male reproductive failure and infertility are quite common in alcoholics. There are very high correlations between elevated vasopressin levels and male infertility on the one hand, and probable deficiencies of prostaglandin E1 which may raise levels of PGE2 and endorphins which, in turn, release vasopressin on the other. Since head-out water immersion rapidly decreases vasopressin levels, a suggested joint protocol of head-out water immersion and a prostaglandin E-1 precursor is proposed for male reproductive failure in alcoholics.
Mount Pleasant Hospital Addiction Studies Foundation, Lynn, Massachusetts.
J
J
Backon
D015126:8,11,14-Eicosatrienoic Acid / Q000627:therapeutic use; D000437:Alcoholism / Q000150:complications*; D000527:Alprostadil / Q000172:deficiency / Q000378:metabolism; D006801:Humans; D007101:Immersion; D007248:Infertility, Male / Q000209:etiology / Q000628:therapy*; D008297:Male; D014667:Vasopressins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D014867:Water
D014867:Water; D014667:Vasopressins; D000527:Alprostadil; D015126:8,11,14-Eicosatrienoic Acid