Parental alcoholism as a risk factor in benzodiazepine abuse: a pilot study.
Nine of 12 men with a family history of alcoholism but only two of 12 control subjects had euphoric responses to alprazolam. The authors conclude that sons of alcoholics may be at high risk to abuse alprazolam.
Ciraulo
D A
DA
Department of Psychiatry, Tufts University School of Medicine, Boston, MA.
Barnhill
J G
JG
Ciraulo
A M
AM
Greenblatt
D J
DJ
Shader
R I
RI
D000328:Adult; D000428:Alcohol Drinking; D000437:Alcoholism / Q000150:complications / Q000235:genetics*; D000525:Alprazolam / Q000009:adverse effects / Q000493:pharmacokinetics; D005059:Euphoria; D006801:Humans; D008297:Male; D010290:Parents; D010865:Pilot Projects; D012307:Risk Factors; D019966:Substance-Related Disorders / Q000209:etiology*
D000525:Alprazolam