[Effect of Corynebacterium parvum preparation on selected immunologic indicators and clinical results in patients with chronic post-traumatic osteomyelitis].
Nineteen patients with chronic post-traumatic staphylococcal osteitis++ of a mean 5-years-clinical course were given intramuscularly 3.5 mg of Coparvax for two weeks. An increase of IgG concentration in the serum, starting from the 8th week of observation, and a marked increase of the ability of absorbtion and destruction of staphylococci by the neutrophils of the peripheral blood have been found. It has been accompanied by subsidence of clinical symptoms of ostitis in 13 patients and a marked decrease of intensity of the inflammatory process in 4 other patients. No effect has been found in two patients.
T
T
Perner
K
K
Zołyjski
A
A
Denys
B
B
Jazdzewski
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000328:Adult; D001428:Bacterial Vaccines; D001688:Biological Products / Q000627:therapeutic use*; D002908:Chronic Disease; D003352:Corynebacterium; D005260:Female; D050723:Fractures, Bone / Q000150:complications; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000209:etiology / Q000276:immunology / Q000628:therapy*; D010587:Phagocytosis; D013203:Staphylococcal Infections / Q000209:etiology / Q000276:immunology / Q000628:therapy*
D000276:Adjuvants, Immunologic; D001428:Bacterial Vaccines; D001688:Biological Products; C039725:Corynebacterium parvum vaccine; D007136:Immunoglobulins
Wpływ preparatu Corynebacterium parvum na wybrane wskaźniki immunologiczne i wyniki kliniczne u chorych na przewlekłe pourazowe zapalenie kości.