Cutaneous vasculitis due to cyclophosphamide therapy for chronic lymphocytic leukemia.
A 55-year-old male with chronic lymphocytic leukemia developed a skin eruption after receiving oral cyclophosphamide. Subsequent rechallenge with parenteral cyclophosphamide led to recurrence of the skin lesions, which on biopsy were shown to be vasculitic in nature.
Green
R M
RM
Queen Elizabeth Hospital, Woodville, SA.
Schapel
G J
GJ
Sage
R E
RE
D000284:Administration, Oral; D002908:Chronic Disease; D003520:Cyclophosphamide / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007945:Leukemia, Lymphoid / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000139:chemically induced*
D003520:Cyclophosphamide