A case of dengue hemorrhagic fever in a Japanese child.
A 6-year-old Japanese girl contracted a febrile illness with hemorrhagic manifestations when she traveled in Indonesia. A remarkable decrease in the numbers of platelets and white blood cells was observed in her acute-phase blood specimens. Her father, who accompanied her, showed dengue fever-like symptoms at almost the same time as her illness. It was determined by serological tests that they were infected with dengue virus type 1. Moreover, she showed a secondary antibody response to the flavivirus due to the pre-existing antibody to Japanese encephalitis virus. This is the first confirmed case of dengue hemorrhagic fever (DHF) in Japanese people.
Department of Preventive Medicine, Osaka University.
Y
Y
Okuno
T
T
Harada
M
M
Ogawa
Y
Y
Okamoto
K
K
Maeda
D002648:Child; D003168:Complement Fixation Tests; D003715:Dengue / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D003716:Dengue Virus / Q000302:isolation & purification; D005260:Female; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007214:Indonesia; D007564:Japan / Q000208:ethnology; D008297:Male; D009500:Neutralization Tests