Gingivitis in the deciduous and permanent dentition. An experimental study in the dog.
The present investigation was performed in order to study the reaction of the gingiva in the deciduous and permanent dentition of dogs to 3 weeks of plaque accumulation. The study was carried out in 10 beagles, divided into 2 groups of 5 dogs each; group I and group II. When the dogs of group I were 10 weeks old, a meticulous plaque control regimen was initiated in order to establish clinically healthy gingiva. After 6 weeks of plaque control, the gingivae of the lower deciduous molars was exposed to a clinical examination, and biopsies as well as bacterial plaque samples were harvested from tooth 03P and 02P. A second plaque control regimen was initiated when the same dogs were 15 months old. After 6 weeks of plaque control, the gingiva of the permanent dentition was examined and biopsies sampled from tooth P3 and P4. In the dogs of group II, plaque control regimens of 3 weeks duration were initiated when the animals were 10 weeks and 15 months old. Clinical examinations were performed at the end of each 3-week period. Immediately after the clinical examinations. 3-week periods of plaque accumulation were initiated. Examinations and plaque sampling were performed after each of these 3-week periods and biopsies were sampled from the deciduous and permanent dentition as described for group I. The biopsies were processed for histometric and morphometric measurements. The findings from the experiment showed that careful plaque control resulted in the establishment of clinically healthy gingiva. In both the deciduous and permanent dentition, however, a clinically healthy gingiva was found to contain a small inflammatory cell infiltrate (ICT). 3 weeks of plaque accumulation resulted in both dentitions in the development of clinical signs of gingivitis and in the formation of comparatively large ICT. The large ICT of the permanent gingiva resided in the coronal portion of the free gingival unit, while in the deciduous dentition, the inflammatory lesion occupied a narrow tissue portion along the entire border of the dento-gingival epithelium. The ICT of the permanent gingiva harbored a larger portion of plasma cells than the inflammatory lesion studied in the deciduous dentition.
Berglundh
T
T
Department of Periodontology, School of Dentistry, University of Gothenburg, Sweden.
Liljenberg
B
B
Ericsson
I
I
Lindhe
J
J
D000818:Animals; D001419:Bacteria / Q000302:isolation & purification; D003238:Connective Tissue / Q000473:pathology; D003773:Dental Plaque / Q000150:complications* / Q000382:microbiology; D004285:Dogs; D004848:Epithelium / Q000033:anatomy & histology / Q000473:pathology; D005881:Gingiva / Q000033:anatomy & histology; D005891:Gingivitis / Q000209:etiology* / Q000473:pathology; D007962:Leukocytes / Q000473:pathology; D007963:Leukocytes, Mononuclear / Q000473:pathology; D009504:Neutrophils / Q000473:pathology; D014070:Tooth; D014094:Tooth, Deciduous