Fatal subarachnoid haemorrhage associated with dental local anaesthesia.
A case is described of sudden death occurring after the use of a noradrenaline-containing local anaesthetic. Autopsy revealed a massive subarachnoid haemorrhage following a ruptured cerebral aneurysm. The noradrenaline in the local anaesthetic is thought to be an important factor in the cause of the rupture. It is recommended that preparations containing 1:25,000 noradrenaline not be used.
Okada
Y
Y
Suzuki
H
H
Ishiyama
I
I
D000766:Anesthesia, Dental / Q000009:adverse effects*; D000779:Anesthetics, Local / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D008875:Middle Aged; D009638:Norepinephrine / Q000009:adverse effects*; D013345:Subarachnoid Hemorrhage / Q000139:chemically induced*; D014081:Tooth Extraction; D014662:Vasoconstrictor Agents / Q000009:adverse effects
D000779:Anesthetics, Local; D014662:Vasoconstrictor Agents; D009638:Norepinephrine