Influence of immunization with allogeneic spleen cells on the number of viable neonates in mice.
Female CBA/J (H-2k) mice mated with male DBA/2J (H-2d) mice show a high level of fetal resorption, which can be reduced by immunization with BALB/c (H-2d) spleen cells. The morphologically defined fetal resorption rate upon which evaluation of the outcome of pregnancy has previously been based in this strain combination is not equivalent to the rate of production of viable neonates.
Heine
O
O
Department of Gynecology and Obstetrics, Justus Liebig-University, Giessen, F.R.G.
Neppert
J
J
Mueller-Eckhardt
G
G
D000026:Abortion, Habitual / Q000276:immunology / Q000628:therapy; D000818:Animals; D004195:Disease Models, Animal / Q000628:therapy; D005260:Female; D005313:Fetal Death / Q000628:therapy*; D005327:Fetal Resorption / Q000628:therapy*; D005333:Fetus / Q000276:immunology; D007108:Immune Tolerance; D007114:Immunization; D007519:Isoantigens / Q000627:therapeutic use*; D008098:Litter Size; D051379:Mice; D008807:Mice, Inbred BALB C / Q000276:immunology; D008808:Mice, Inbred CBA / Q000276:immunology; D008811:Mice, Inbred DBA / Q000276:immunology; D011247:Pregnancy; D013154:Spleen / Q000276:immunology*
D007519:Isoantigens