Normalization of skin appearance in a patient with scleromyxoedema after intensive chemotherapy for Hodgkin's disease.
A patient with scleromyxoedema was treated for 6 years with cytostatic drugs. During this time the skin lesions followed a fluctuating but progressive course. After 6 years she developed Hodgkin's lymphoma of the mixed cellularity type. Intensive cytostatic treatment given for Hodgkin's disease resulted in virtually complete disappearance of the scleromyxoedema lesions. The development of Hodgkin's disease is considered fortuitous and not due to the previous cytostatic drugs.
Alberts
A S
AS
Department of Medical Oncology, University of Pretoria, South Africa.
Schulz
E J
EJ
Falkson
G
G
Simson
I W
IW
Coccia-Portugal
M A
MA
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D005260:Female; D006689:Hodgkin Disease / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D009230:Myxedema / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D012594:Scleroderma, Localized / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D012867:Skin / Q000473:pathology