[Purulent meningitis in childhood caused by Haemophilus influenzae with ampicillin and chloramphenicol resistance].
A report is given on two children suffering from meningitis caused by ampicillin- and chloramphenicol-resistent Haemophilus influenzae. Since effective therapy has been started with delay, recovery was affected with complications. The need for the early determination of minimal inhibitory concentrations and detection of beta-lactamase-production is emphasized as well as for repeated measurement of C-reactive protein in serum. Cefotaxime is recommended in case of presence of resistent Haemophilusstrains.
Rockstroh
T
T
Noack
R
R
Scholz
H
H
D000668:Ampicillin Resistance; D002439:Cefotaxime / Q000627:therapeutic use*; D002702:Chloramphenicol Resistance; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007223:Infant; D008583:Meningitis, Haemophilus / Q000188:drug therapy*
D002439:Cefotaxime
Meningitis purulenta im Kindesalter durch Haemophilus influenzae mit Ampicillin- und Chloramphenicolresistenz.