[Various immunologic indices in primary chronic adrenal insufficiency].
Patients with primary chronic adrenal insufficiency (PCAI) in decompensation demonstrated a decrease in the total level of blood immunoglobulins, in particular IgG, with the normal level of B-lymphocytes. A decrease in IgG and an increase in IgA content was noted in the eucorticoid state; relative and absolute lymphocytosis determined by an increase in T- and B-lymphocytes was also noted. In overdosage of cortisone acetate the total number of immunoglobulins was normal, but IgA was raised and IgG lowered. The number of B-lymphocytes was significantly elevated. The number of T-lymphocytes was within normal but an increase in the level of T-suppressors was noted.
Sil'nitskiĭ
P A
PA
Shabanova
L F
LF
Georgadze
E R
ER
Sirotina
V V
VV
D000309:Adrenal Insufficiency / Q000188:drug therapy / Q000276:immunology*; D000328:Adult; D000917:Antibody Formation; D003348:Cortisone / Q000031:analogs & derivatives / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000032:analysis*; D007958:Leukocyte Count; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged
D007136:Immunoglobulins; D003348:Cortisone
Nekotorye immunologicheskie pokazateli pri pervichnoĭ khronicheskoĭ nedostatochnosti nadpochechnikov.