Incidence and characterization of canine rheumatoid factor.
Rheumatoid factor (RF) was found in titers greater than 1:8 in 72.2% of cases of classical or definite canine rheumatoid arthritis (RA) and in 5.9% or normal sera. Serum fractionation and immunoabsorbant studies that much of the RF present was IgG, although activity was demonstrated in all 3 major immunoglobulin classes. Evidence of involvement of both IgG and IgM to form complexes of varying sizes was obtained.
Halliwell
R E
RE
Department of Medical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610.
Werner
L L
LL
Baum
D E
DE
Newton
C D
CD
Wolfe
J H
JH
Schumacher
H R
HR
D000818:Animals; D000906:Antibodies; D000936:Antigen-Antibody Complex / Q000302:isolation & purification; D001172:Arthritis, Rheumatoid / Q000276:immunology / Q000662:veterinary*; D004283:Dog Diseases / Q000276:immunology*; D004285:Dogs; D007074:Immunoglobulin G / Q000302:isolation & purification; D007075:Immunoglobulin M / Q000302:isolation & purification; D008970:Molecular Weight; D012217:Rheumatoid Factor / Q000302:isolation & purification*; D013696:Temperature
D000906:Antibodies; D000936:Antigen-Antibody Complex; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D012217:Rheumatoid Factor