[Comparative evaluation of the black foam film method for determining lung surfactant maturity in the newborn infant].
The present study evaluates a recently introduced method of black foam film (BFF) for determination of lung maturity, adapted for examination of nasopharyngeal aspirate (NFA) in the newborn and as well as to discover its diagnostic value by clinical verification and comparison with the method of total phospholipids (TPL) and with the ratio of lecithin/sphingomyelin (L/S). Comparing the results, obtained by the various methods, it was found that the capability of NFA of the newborn children to form BFF reflected the content of TPL and the ratio of L/S. The good correlation with the clinical state respectively with respiratory function of the examined children indicates the possibility that the method of BFF could be used for postnatal evaluation of lung maturity.
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Zhekova
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Lalchev
D005069:Evaluation Studies as Topic; D005325:Fetal Organ Maturity; D006801:Humans; D006819:Hyaline Membrane Disease / Q000175:diagnosis; D007231:Infant, Newborn; D008168:Lung / Q000196:embryology*; D008722:Methods; D009305:Nasopharynx; D010713:Phosphatidylcholines / Q000032:analysis; D010743:Phospholipids / Q000032:analysis; D011663:Pulmonary Surfactants / Q000032:analysis*; D013109:Sphingomyelins / Q000032:analysis
D010713:Phosphatidylcholines; D010743:Phospholipids; D011663:Pulmonary Surfactants; D013109:Sphingomyelins
Sravnitelna otsenka na metoda za cherniia penen film za opredeliane zrelostta na belodrobniia sŭrfaktant u novorodenoto.