[Biochemical and electrophysiological correlations of functional asymmetry of the brain].
Biochemical differences in metabolic activity between the two hemispheres are manifested by a higher level of free fatty acids in the left hemisphere. Differences in the concentration of transmitters concern higher levels of norepinephrine, dopamine, choline acetyltransferase and GABA in some regions of the left hemisphere. Lesions in homologous areas of the right and left hemisphere do not have the same effect on the biochemical activity of the brain. Amobarbital and alcohol reduce the activity of the right hemisphere. The criteria used to establish electrophysiologic differences in the activity of the two hemispheres are as follows: evaluation of the value of basic activity, suppression of alpha activity, evoked potential parameters, and the degree of negativity of slow brain potentials. Signs of higher activity of the right hemisphere were recorded at visuo-spatial performances and of higher activity of the left hemisphere at verbal performance. Extracerebrally only slight electrodermal differences were observed between the right and left side of the body.
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Cernácek
D001921:Brain / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*; D004594:Electrophysiology; D007839:Functional Laterality; D006801:Humans
Biochemické a elektrofyziologické koreláty funkcnej asymetrie mozgu.