[Magnetic resonance tomography of the breast. The results of 253 examinations].
Requirements for diagnostic magnetic resonance imaging (MRI) of breast disease were defined on the basis of 253 examinations over 4 1/2 years. The results were compared with those of mammography in 207, with histological findings in 145 cases. Examinations after injection of 0.1 mmol/kg Gd-DTPA (gadolinium diethylene-triamino-penta-acetate) and measurement of the same sections at short intervals proved to be the most informative MRI technique for the differentiation of benign and malignant changes. Carcinomas had a rapid initial rise in signal of more than 90% over the pre-injection level within one minute of contrast-medium administration. In 163 of 207 cases MRI provided information additional to mammography (confirmation or exclusion of a carcinoma; exact localization of a malignant process; differentiation between carcinoma and scar tissue; diagnosis of a tumour close to the thoracic cavity; changes near a prosthesis). Analysing only the examinations done with contrast-medium (144), there was a 99% sensitivity. There have been no false-negatives so far. Despite the high cost and time required, MRI of the breast is indicated when mammography, ultrasound and clinical features provide unclear and (or) discrepant findings.
Radiologisches Zentrum, Abteilung Diagnostik, Klinikum Nürnberg.
W A
WA
Kaiser
D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000175:diagnosis; D003287:Contrast Media; D005069:Evaluation Studies as Topic; D005188:False Negative Reactions; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008327:Mammography; D009942:Organometallic Compounds; D004369:Pentetic Acid; D013997:Time Factors
D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA
Magnetresonanztomographie der Mamma. Erfahrungen nach 253 Untersuchungen.