Alport's syndrome and the eye.
Alport's syndrome comprises hereditary deafness, nephritis and ocular abnormalities. The features of Alport's syndrome are illustrated by a family with Alport's syndrome and hereditary oesophageal leiomyomatosis. The evidence that Alport's syndrome is due to a widespread basement membrane disorder is noted. Treatment of anterior lenticonus, the principal ocular abnormality, by lensectomy and intraocular lens insertion is recommended.
Department of Ophthalmology, Prince of Wales Hospital, New South Wales.
P J
PJ
McCartney
R
R
McGuinness
D000328:Adult; D004938:Esophageal Neoplasms / Q000151:congenital*; D006801:Humans; D007889:Leiomyoma / Q000151:congenital*; D007908:Lens, Crystalline / Q000002:abnormalities* / Q000601:surgery; D007910:Lenses, Intraocular; D008297:Male; D009394:Nephritis, Hereditary / Q000235:genetics / Q000473:pathology*