Molecular hybridization with DNA probes as a laboratory diagnosis test for influenza viruses: further investigations on the possibilities of the method.
The possibilities of the molecular hybridization test, i.e. test, i.e. using neuraminidase probes of different subtypes for subtype specific detection of influenza, as well as different probes (PA, M, NP) for type A specific detection of influenza viruses in infected cells were shown. The results of molecular hybridization in washings' analyses from patients during the outbreaks give us an opportunity to make some conclusions about the usefulness of the method in epidemic control of influenza morbidity.
Pljusnin
A Z
AZ
Leningrad Pasteur Institute of Epidemiology and Microbiology, Ministry of Health, USSR.
Nolandt
O V
OV
Bryantseva
E A
EA
Kuznetsova
E V
EV
Fridman
E A
EA
Noskov
F S
FS
D000293:Adolescent; D000328:Adult; D000818:Animals; D002648:Child; D015342:DNA Probes / Q000032:analysis*; D004279:DNA, Viral / Q000235:genetics*; D005814:Genes, Viral; D006801:Humans; D009980:Influenza A virus / Q000235:genetics* / Q000302:isolation & purification; D009981:Influenza B virus / Q000235:genetics* / Q000302:isolation & purification; D007251:Influenza, Human / Q000175:diagnosis / Q000382:microbiology; D009305:Nasopharynx / Q000382:microbiology; D009439:Neuraminidase / Q000235:genetics; D009693:Nucleic Acid Hybridization; D010957:Plasmids; D014776:Virus Cultivation / Q000379:methods
D015342:DNA Probes; D004279:DNA, Viral; D009439:Neuraminidase