In vitro activity of cefteram against predominantly enteropathogenic and glucose nonfermentative gram-negatives.
Cefteram (T-2525), the free acid of the orally active cephalosporin ester cefteram pivoxil, was tested in vitro against 355 gram-negative clinical isolates of enteropathogenic and nonfermentative species. The compound was several times more active (w/w) against isolates belonging to the enteropathogenic Enterobacteriaceae and Vibrionaceae than against those belonging to the nonfermentative rods (excluding Pseudomonas aeruginosa).
Pharmaceutical Research Department, F. Hoffmann-La Roche, Basel, Switzerland.
P
P
Hohl
A
A
von Graevenitz
J
J
Zollinger-Iten
D015281:Cefmenoxime / Q000031:analogs & derivatives* / Q000494:pharmacology; D005285:Fermentation; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D008826:Microbial Sensitivity Tests
C049493:cefteram; D015281:Cefmenoxime