[Regulation of the phases of slow-wave ureteral activity by sodium and calcium ions].
The ionic nature of each of the two slow wave depolarization phases of cat's ureter pacemaker during i.a. perfusion of kidneys, was studied. An increase of the calcium ions concentration led to an increase in the second wave phase amplitude, lengthening of the first phase and a decrease in the wave generation frequency. A decrease of the sodium ion concentration also led to an increase in the oscillation frequency with a corresponding shortening of the first phase. In sodium-free solution, during a short interval of time slow wave generation was observed which represented usually the second wave component. But for the autooscillations to get steady, the presence of sodium ions in medium is necessary. The Na+/Ca++ system seems to participate in the generation of the first wave phase.
Kazarian
K V
KV
Vantsian
V Ts
VTs
Martirosov
S M
SM
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D002118:Calcium / Q000494:pharmacology / Q000502:physiology*; D002415:Cats; D003470:Culture Media; D066298:In Vitro Techniques; D008297:Male; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology*; D012964:Sodium / Q000494:pharmacology / Q000502:physiology*; D014513:Ureter / Q000187:drug effects / Q000502:physiology*
D003470:Culture Media; D012964:Sodium; D002118:Calcium
O reguliatsii faz medlennovolnovoĭ aktivnosti mochetochnika ionami natriia i ka'ltsiia.