[The development and duration of immunity in children vaccinated against measles with the Edmonston-Zagreb vaccine].
After routine measles-rubella-mumps (MRM) vaccine, seroconversion rate for measles heminhibiting (HI) antibodies in a group of 161 children was determined. Of the 154 children who had no HI antibodies in the first serum sample, 153 (99.3%) developed these antibodies in titres greater than or equal to 1:4 and 148 (96.1%) in titres greater than or equal to 1:8 at 6 weeks postvaccination. These results are in concord with the WHO standards. Another study was designed to evaluate persistence of HI antibodies to measles in a group of 123 children who were given MRM vaccine 1-6 years earlier. No significant decrease in HI antibody titers was recorded. It is concluded that immunity acquired through vaccination with the Edmonston-Zagreb measles virus strain in children aged 12 months to 3 years is satisfactory and that it does not decrease at least up to 6 years following vaccination.
B
B
Borcić
S
S
Smerdel
J
J
Abu Eldan
J
J
Kolić
M
M
Ferdebar
D
D
Kordić
N
N
Mohacek
D000914:Antibodies, Viral / Q000032:analysis*; D004338:Drug Combinations / Q000276:immunology; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007109:Immunity; D007223:Infant; D008457:Measles / Q000517:prevention & control; D008458:Measles Vaccine / Q000276:immunology*; D008459:Measles virus / Q000276:immunology*; D022542:Measles-Mumps-Rubella Vaccine; D009108:Mumps Vaccine / Q000276:immunology*; D012411:Rubella Vaccine / Q000276:immunology*; D013997:Time Factors
D000914:Antibodies, Viral; D004338:Drug Combinations; D008458:Measles Vaccine; D022542:Measles-Mumps-Rubella Vaccine; D009108:Mumps Vaccine; D012411:Rubella Vaccine
Stvaranje i trajanje imunosti u djece cijepljene protiv ospica vakcinom Edmonston-Zagreb.