Incidence and characterization of canine rheumatoid factor.
Rheumatoid factor (RF) was found in titers greater than 1:8 in 72.2% of cases of classical or definite canine rheumatoid arthritis (RA) and in 5.9% or normal sera. Serum fractionation and immunoabsorbant studies that much of the RF present was IgG, although activity was demonstrated in all 3 major immunoglobulin classes. Evidence of involvement of both IgG and IgM to form complexes of varying sizes was obtained.
Department of Medical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610.
R E
RE
Halliwell
L L
LL
Werner
D E
DE
Baum
C D
CD
Newton
J H
JH
Wolfe
H R
HR
Schumacher
D000818:Animals; D000906:Antibodies; D000936:Antigen-Antibody Complex / Q000302:isolation & purification; D001172:Arthritis, Rheumatoid / Q000276:immunology / Q000662:veterinary*; D004283:Dog Diseases / Q000276:immunology*; D004285:Dogs; D007074:Immunoglobulin G / Q000302:isolation & purification; D007075:Immunoglobulin M / Q000302:isolation & purification; D008970:Molecular Weight; D012217:Rheumatoid Factor / Q000302:isolation & purification*; D013696:Temperature
D000906:Antibodies; D000936:Antigen-Antibody Complex; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D012217:Rheumatoid Factor