Antigenic relationship between the dermonecrotic toxins produced by Pasteurella multocida type D and type A.
Crude dermonecrotic toxins (DNT) were prepared from Pasteurella multocida (P.m.) type D and type A strains isolated from pigs with atrophic rhinitis. Rabbits were immunized with the DNT of P.m. type D. This serum neutralized the DNT of P.m. type A to the same degree as the homologous one both in vitro (cytopathogenicity for tissue culture cells) and in vivo (mouse lethality and dermonecrotic activity in guinea pig).
Frymus
T
T
Müller
E
E
Petzoldt
K
K
D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology*; D001427:Bacterial Toxins / Q000276:immunology*; D003885:Dermotoxins / Q000276:immunology*; D006168:Guinea Pigs; D051379:Mice; D009500:Neutralization Tests; D010325:Pasteurella / Q000378:metabolism*; D011817:Rabbits
D000942:Antigens, Bacterial; D001427:Bacterial Toxins; D003885:Dermotoxins