[H3-dopamine release in experimental mild cranio-cerebral trauma].
The studies of ELCCT influence on spontaneous and KCl-stimulated 3H-dopamine release by synaptosomes isolated from the rabbit brain hemispheres and diencephalic-brainstem areas are presented in this paper. Kinetic characteristics of the releasing system (Bm and Vo) were shown to decrease at earlier stages (15 minutes to 2 hrs) and increase at later stages (1 to 14 days). No substantial difference was shown in release responses of the synaptosomes derived from brain hemispheres and diencephalic-brainstem regions. The data suggest the major alterations in the mechanisms of dopamine release in ELCCT.
V P
VP
Parkhomets
A N
AN
Vasi'lev
M V
MV
Ruchko
D000818:Animals; D001921:Brain / Q000378:metabolism* / Q000648:ultrastructure; D001930:Brain Injuries / Q000473:pathology / Q000503:physiopathology*; D001933:Brain Stem / Q000378:metabolism / Q000648:ultrastructure; D004298:Dopamine / Q000378:metabolism*; D011817:Rabbits; D013574:Synaptosomes / Q000378:metabolism*; D013997:Time Factors
D004298:Dopamine
Vysvobozhdenie 3H-dofamina v dinamike éksperimenta'lnoĭ legkoĭ cherepno-mozgovoĭ travmy.