The Korotkoff sound.
As the auscultatory method of blood pressure measurement relies fundamentally on the generation of the Korotkoff sound, identification of the responsible mechanisms has been of interest ever since the introduction of the method, around the turn of the century. In this article, a theory is proposed that identifies the cause of sound generation with the nonlinear properties of the pressure-flow relationship in, and of the volume compliance of the collapsible segment of brachial artery under the cuff. The rising portion of a normal incoming brachial pressure pulse is distorted due to these characteristics, and energy contained in the normal pulse is shifted to the audible range. The pressure transient produced is transmitted to the skin surface and stethoscope through deflection of the arterial wall. A mathematical model is formulated to represent the structures involved and to compute the Korotkoff sound. The model is able to predict quantitatively a range of features of the Korotkoff sound reported in the literature. Several earlier theories are summarized and evaluated.
Drzewiecki
G M
GM
Department of Biomedical Engineering, College of Engineering, Rutgers University, Piscataway, NJ 08855-0909.
Melbin
J
J
Noordergraaf
A
A
D001314:Auscultation / Q000295:instrumentation; D001794:Blood Pressure; D001795:Blood Pressure Determination / Q000379:methods*; D001916:Brachial Artery / Q000502:physiology*; D006801:Humans; D008955:Models, Cardiovascular; D008962:Models, Theoretical; D011674:Pulse; D012039:Regional Blood Flow