Inheritance of low plasma cholinesterase activity in two families with a history of suxamethonium sensitivity.
An hypothesis advanced in 1970 concerning family inheritance of low enzymic activities of plasma cholinesterase has been substantiated. The recognition of three E1kE1s genotypes is reported in this family after investigation of a new generation. A second family with similar genetic characteristics is described.
Whittaker
M
M
Department of Chemistry, University of Exeter.
Berry
M
M
Britten
J J
JJ
D002802:Cholinesterases / Q000097:blood / Q000172:deficiency / Q000235:genetics*; D005838:Genotype; D006801:Humans; D010375:Pedigree; D013390:Succinylcholine
D002802:Cholinesterases; D013390:Succinylcholine