Platelet transfusion therapy in thrombocytopaenia of haematologic malignancies.
Thirty thrombocytopaenic patients of acute leukaemias and myelodysplastic syndrome were transfused platelets collected from ABO-matched donors using Haemonetics V30 and V50 blood processors. Twenty-seven patients had septicaemia and/or splenomegaly; 2 patients had disseminated intravascular coagulation (DIC). Pre-transfusion platelet count was 11.0 +/- 4.0 X 10(9)/L. The mean corrected count increments (CCI) 1 hour and 18 hours post-transfusion were 13.02 X 10(9)/L and 3.88 X 10(9)/L respectively, in the absence of DIC. Active bleeding stopped when platelet count was above 15.0 X 10(9)/L. There was no difference between the platelet yield from two blood processors.
Charak
B S
BS
Rao
K
K
Parikh
P M
PM
Rawat
R S
RS
Nair
C N
CN
Advani
S H
SH
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001803:Blood Transfusion; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007938:Leukemia / Q000150:complications*; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000150:complications*; D017713:Platelet Transfusion; D013921:Thrombocytopenia / Q000209:etiology / Q000517:prevention & control*