[Neurocutaneous melanosis].
The authors report on a patient of 33 years of age suffering from neurocutaneous melanosis in whom two years after excision of a naevus pigmentosus et pilosus giganteus cellular proliferation of the melanoblasts in the area of the soft meninges was seen. This process led to the death of the patient within a few weeks' time despite intensive therapeutic measures, the manifestation being that of a generalised space-occupying growth in the CNS. Neuroradiological techniques can objectify the clinical pattern of signs of this very rare disease and may possibly enable an early diagnosis.
Klinik und Poliklinik für Neurologie der Westf. Wilhelmsuniversität Münster.
I W
IW
Husstedt
K H
KH
Grotemeyer
M
M
Galanski
H P
HP
Schlake
D000328:Adult; D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis*; D008577:Meningeal Neoplasms / Q000175:diagnosis*; D008578:Meninges / Q000473:pathology; D009192:Myelography; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D009508:Nevus, Pigmented / Q000175:diagnosis*; D012878:Skin Neoplasms / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed
Zur neurokutanen Melanose.