[Levels of blood theophylline in patients with acute bronchospasm].
Plasma theophylline levels (mcg/ml) of 93 patients with a bronchopulmonary disease (asthma and chronic obstructive lung disease) who were on theophylline (normal or retarded) treatment, were determined on admission at the emergency ward because of acute bronchospasm. Our results show that theophylline blood levels were subtherapeutical in patients treated either with normal (2.1 +/- 0.8 mcg/ml) or retarded theophylline (9.6 +/- 1.3 mcg/ml). This was probably due to insufficient dosing and/or poor patient compliance. The necessity of monitoring this type of treatment is once again evident.
Martínez
M J
MJ
Martínez
B
B
Saucedo
R
R
García Delgado
R
R
García Morillas
M
M
Puche
E
E
D000208:Acute Disease; D000368:Aged; D001249:Asthma / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D001986:Bronchial Spasm / Q000097:blood / Q000209:etiology*; D003692:Delayed-Action Preparations; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D013806:Theophylline / Q000008:administration & dosage / Q000097:blood* / Q000627:therapeutic use
D003692:Delayed-Action Preparations; D013806:Theophylline
Tasas de teofilinemia en pacientes con un broncoespasmo agudo.