Plasmid profiles of Mycobacterium avium complex isolated from swine.
Twenty strains of Mycobacterium avium complex (MAC) isolated from swine and five strains from humans were examined for drug susceptibility and plasmid content. Four strains of swine origin and two strains of human origin harbored plasmid DNAs differing in molecular weights. No relationship between plasmid contents and drug resistance was observed. Southern DNA-DNA hybridization showed that small plasmids from swine MAC strains were homologous to those from human origin at the nucleotide level.
Aburahi Laboratories Shionogi & Ltd., Shiga.
S
S
Masaki
T
T
Konishi
G
G
Sugimori
A
A
Okamoto
Y
Y
Hayashi
F
F
Kuze
D000818:Animals; D000995:Antitubercular Agents / Q000494:pharmacology; D015139:Blotting, Southern; D004269:DNA, Bacterial / Q000032:analysis; D004352:Drug Resistance, Microbial / Q000235:genetics*; D004587:Electrophoresis, Agar Gel; D006801:Humans; D008826:Microbial Sensitivity Tests; D009162:Mycobacterium avium / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D015269:Mycobacterium avium Complex / Q000235:genetics; D011815:R Factors; D013552:Swine / Q000382:microbiology*
D000995:Antitubercular Agents; D004269:DNA, Bacterial