Endocrine dysfunction in lymphomatoid granulomatosis.
Endocrine abnormalities in lymphomatoid granulomatosis are rare and have never been a major determinant of the clinical course. We describe three patients who illustrate that a wide range of endocrine dysfunction (hypoadrenalism, hypercalcemia, hypothyroidism, diabetes insipidus and hypogonadism) may be encountered in this disorder. Moreover, such endocrine manifestations may be the major feature at presentation, the treatment of which may significantly influence the subsequent clinical outcome.
Royal Perth Hospital, WA.
P J
PJ
Leedman
L R
LR
Matz
P
P
Pullan
D000293:Adolescent; D000309:Adrenal Insufficiency / Q000150:complications; D000328:Adult; D000368:Aged; D002648:Child; D003919:Diabetes Insipidus / Q000150:complications; D004700:Endocrine System Diseases / Q000150:complications*; D006801:Humans; D006934:Hypercalcemia / Q000150:complications; D007006:Hypogonadism / Q000150:complications; D007037:Hypothyroidism / Q000150:complications; D008230:Lymphomatoid Granulomatosis / Q000150:complications* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed