[Clinical evaluation of immunosuppressive factors (IAP-immunosuppressive acidic protein, IS-immunosuppressive substance) in head and neck cancer].
It is reported that the levels of serum IAP and IS are useful parameters to evaluate the prognosis along with the clinical course of tumor bearing patients. Serum IAP and IS were examined in 149 patients with head and neck cancer. The level of serum IAP and IS increased in patients with not only advanced stages, but also poor prognosis. In general, the patients with death or recurrence had higher levels of serum IAP and IS than those with good prognosis. It is concluded that serum IAP and IS well reflect the immunological condition and clinical course of patients with cancer and may be one of the useful parameter for them.
Saito
T
T
Dake
Y
Y
Kakiuti
H
H
Kato
Y
Y
Kuki
K
K
Hayashi
Y
Y
Yokota
M
M
Kinoshita
K
K
Kuki
S
S
Kimura
T
T
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006023:Glycoproteins / Q000032:analysis*; D006258:Head and Neck Neoplasms / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000032:analysis* / Q000097:blood*
D006023:Glycoproteins; D009363:Neoplasm Proteins; C030193:immunosuppressive acidic protein; C038588:serum immunosuppressive factor, human