[Clinico-immunological characteristics of patients with ocular toxoplasmosis].
The results of clinical observations on 34 patients with toxoplasmosis affecting mainly eyes over the period of 2-6 years are presented. The presence of antibodies to Toxoplasma, the content of IgA, IgM and IgG, as well as a number of characteristics of the T and B immunity systems in these patients were determined in their dynamics. For control, similar characteristics were determined in 28 practically healthy persons. During the period of observation the patients showed multiple fluctuations in the level of titers of serological reactions with toxoplasmic antigens and changes in the severity of the clinical picture. In contrast to healthy persons, toxoplasmosis patients were found to have statistically significant changes in a number of characteristics of the T immunity system. The content of B lymphocytes remained within normal limits. Complex treatment with the use of immunostimulating agents proved to be effective only in some of the patients.
Shcheulov
A P
AP
Fedorchenko
A M
AM
Varenko
Iu S
IuS
Povolotskaia
V I
VI
D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis; D000917:Antibody Formation / Q000187:drug effects; D002908:Chronic Disease; D003049:Coccidiostats / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D008297:Male; D012008:Recurrence; D014122:Toxoplasma / Q000276:immunology; D014126:Toxoplasmosis, Ocular / Q000188:drug therapy / Q000276:immunology*
D000276:Adjuvants, Immunologic; D000913:Antibodies, Protozoan; D003049:Coccidiostats
Kliniko-immunologicheskaia kharakteristika bol'nykh toksoplazmozom glaz.