Improvement of anemia in patients on chronic dialysis treated by hemodiafiltration.
A group of patients with severe anemia on standard hemodialysis were transferred to polyacrylnitrile hemodiafiltration (HDF), which was arranged in order to obtain an ultrafiltration rate (UF) higher than 100 ml/min. During HDF, despite a significant reduction of the dialysis time, all patients had a significant decrease of predialytic BUN and serum creatinine, and a significant improvement of anemia. Furthermore, a close direct correlation was detected between the percent increase of hemoglobin and the length of time on HDF. Therefore, high-UF HDF represents a valid dialytic strategy to improve anemic states, permitting a significant reduction of the dialysis time and, thus, offering a better life quality for the patients.
Gonella
M
M
Servizio di Nefrologia e Dialisi, Ente Ospedaliero, Casale Monferrato, Italia.
Pratesi
G
G
Calabrese
G
G
Vagelli
G
G
Mazzotta
A
A
D000740:Anemia / Q000209:etiology / Q000628:therapy*; D001794:Blood Pressure; D005260:Female; D006440:Hemofiltration; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*