Serum levels of some fat metabolism parameters in women with uterine leiomyoma.
Serum levels of total cholesterol (TC), HDL-cholesterol (HDL-C), triglycerides (TG) and, 17 beta-estradiol (E2), as well as the values of LDL1-cholesterol (LDL1-C), HDL-C/TC, and HDL-C/LDL1-C were determined in 72 patients with uterine leiomyoma and 45 healthy women aged 34-54. The subjects were divided into three groups according to age and menstrual status (B1I-III). The patients were further subdivided into groups N and P, depending on the leiomyoma size, in order to assess the intensity of the pathogenic process. The values of cholesterol parameters (CT, HDL-C) showed a statistically significant increase in the youngest patients. The study also confirmed the opinion that hyperestrogenism could play a role in the etiopathogenesis of uterine leiomyoma.
1st Department of Obstetrics and Gynaecology, Silesian School of Medicine, Bytom, Poland.
J
J
Rzempołuch
B T
BT
Kamiński
R
R
Wawryk
A
A
Wiczkowski
L
L
Dyla
M
M
Sobolewska
D000328:Adult; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D004958:Estradiol / Q000097:blood; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000097:blood*; D008055:Lipids / Q000097:blood*; D008875:Middle Aged; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood; D014594:Uterine Neoplasms / Q000097:blood*
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D014280:Triglycerides; D004958:Estradiol; D002784:Cholesterol