[Severe hypopotassemia and rhabdomyolysis in a normotensive subject after use of a nasal spray containing 9-alpha-fluoroprednisolone].
We report the case of a 16-year-old boy who was admitted to our hospital for acute urinary retention, flaccid paralysis of the legs and arms and rhabdomyolysis due to a nasal spray containing 9-alpha-fluoroprednisolone. In our normotensive subject, rhabdomyolysis occurred after vigorous physical activity performed before the administration. The case emphasizes the need to avoid the use of 9-alpha-fluoroprednisolone considering its intense mineralocorticoid activity.
Wu
S C
SC
Secchi
M B
MB
Mancarella
S
S
Oltrona
L
L
Bettazzi
L
L
Sale
M
M
Ambrosi
B
B
D000281:Administration, Intranasal; D000293:Adolescent; D005477:Fluprednisolone / Q000008:administration & dosage / Q000009:adverse effects* / Q000031:analogs & derivatives; D006801:Humans; D007008:Hypokalemia / Q000139:chemically induced*; D008297:Male; D010243:Paralysis / Q000139:chemically induced*; D012206:Rhabdomyolysis / Q000139:chemically induced*; D014555:Urination Disorders / Q000139:chemically induced*
C010958:9-fluoroprednisolone; D005477:Fluprednisolone
Severa ipopotassiemia e rabdomiolisi da uso di spray nasale contenente 9-alfa-fluorprednisolone in soggetto normoteso.