[Disseminated intravascular coagulation disorder in the 2d trimester of pregnancy. Case report from the 16th week of pregnancy with spontaneous parturition at term].
After exercising on a trampoline, a 29-year-old primigravidae in the 16th week of gestation was admitted to our hospital with the clinical signs of premature ablatio placentae and acute coagulation disturbances with disseminated intravascular coagulation and uncontrolled secondary hyperfibrinolysis. The coagulation disturbance was stabilized by conservative therapy (Substitution with fresh-frozen-plasma (ffp), whole blood and low-dose heparin treatment without having to terminate the pregnancy by evacuation of the uterus. An appropriate antifibrinolytic treatment was not performed in this case. The continuous controls of fibrinmonomeres and reptilase time indicate the possibility of a persisting latent coagulation disturbance after the acute phase. Thus, the necessity of a low-dose heparin therapy after an acute coagulation disturbance becomes evident.
Universitäts-Frauenklinik Freiburg.
H J
HJ
Prömpeler
C
C
Wilhelm
H P
HP
Zahradnik
K
K
Hasler
H G
HG
Hillemanns
D000033:Abortion, Threatened / Q000097:blood*; D000328:Adult; D001780:Blood Coagulation Tests; D001803:Blood Transfusion; D003131:Combined Modality Therapy; D004211:Disseminated Intravascular Coagulation / Q000097:blood* / Q000628:therapy; D015444:Exercise; D005260:Female; D005342:Fibrinolysis; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood* / Q000628:therapy; D011262:Pregnancy Trimester, Second; D012307:Risk Factors; D014592:Uterine Hemorrhage / Q000097:blood* / Q000628:therapy
D006493:Heparin
Disseminierte intravasale Gerinnungsstörung im II. Schwangerschafts-Trimenon. Fallbericht aus der 16. SSW mit Spontangeburt am Endtermin.