[Experimental study of antigastroesophageal reflux by preservation of the lower esophageal sphincter].
Gastroesophageal reflux and its resultant esophagitis are common complications following removal of the middle and lower part of the esophagus as well as the gastric cardia with reconstruction by simple esophagogastrostomy. Twenty-one dogs were randomly divided into 3 groups: (1) LES preserving group; (2) Nissen's fundoplication group; (3) Sweet's esophagogastrostomy group. Results by esophageal manometry, X-ray video tape recorder, and pathological examination respectively, 3 months postoperatively were compared. Esophageal manometry showed that the pressure of the preserved LES was still present. X-ray video tape recorder revealed that antireflex function was present in the preserved LES. Pathological examination confirmed no signs of reflux esophagitis in the mucosal specimen of the preserved LES group. We concluded that LES is the main barrier of gastroesophageal reflux. The intrathoracic LES could still have the function of anti-reflux.
Yan
Y
Y
D000818:Animals; D004285:Dogs; D004942:Esophagitis, Peptic / Q000517:prevention & control; D004943:Esophagogastric Junction / Q000601:surgery*; D004947:Esophagus / Q000503:physiopathology / Q000601:surgery*; D005764:Gastroesophageal Reflux / Q000517:prevention & control*; D008365:Manometry; D011183:Postoperative Complications / Q000517:prevention & control