[Cytogenetic relationship between portal fibroblasts and Ito cells of the liver].
Portal fibroblasts of normal human and rat liver were morphologically investigated to estimate their capability of storing vitamin A. Vitamin A levels were semiquantitatively estimated by evaluation of the number and size of intracellular lipid droplets. Vitamin A storage was found to be low in more than 10% of normal portal fibroblasts in man and rat. Lipidstoring fibroblasts of portal tracts exhibited remarkable morphological similarities to "activated" Ito cells and were accordingly designated as portal transitional cells.
Kliniksbereich I der Klinik und Poliklinik für Innere Medizin, Martin-Luther-Universität Halle-Wittenberg, DDR.
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Rath
D000818:Animals; D005347:Fibroblasts / Q000032:analysis / Q000378:metabolism / Q000648:ultrastructure*; D006801:Humans; D008055:Lipids / Q000032:analysis; D008099:Liver / Q000032:analysis / Q000166:cytology* / Q000378:metabolism; D008854:Microscopy, Electron; D051381:Rats; D014801:Vitamin A / Q000032:analysis
D008055:Lipids; D014801:Vitamin A
Zytogenetische Beziehung zwischen portalen Fibroblasten und Ito-Zellen der Leber.