[Tolerogenic effect of ovalbumin digestion products forming in the gastrointestinal tract of rats].
The authors studied the tolerogenic effect of ovalbumin digestion products absorbed into the blood from the gastrointestinal tract of rats and injected intravenously into mice 24 hours before immunization of these animals with native protein. The preparation is a fraction with a molecular mass of no less than 6,000 daltons obtained by gel filtration of blood serum of ovalbumin fed rats on a column with Sephadex G-25. The titer of antibodies to ovalbumin determined by the passive hemagglutination test reduced on the 14th and 20th days after parenteral immunization with native ovalbumin.
Shirina
L I
LI
Mazo
V K
VK
Salamatova
S A
SA
D000818:Animals; D004063:Digestion; D004064:Digestive System / Q000276:immunology*; D008297:Male; D010047:Ovalbumin / Q000276:immunology* / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains
D010047:Ovalbumin
Tolerogennyĭ éffekt produktov perevarivaniia oval'bumina, obrazuiushchikhsia v zheludochno-kishechnom trakte krys.