Efficacy of diclazuril against turkey coccidiosis in dose-titration studies.
Diclazuril, a new anticoccidial drug, was tested for its efficacy in turkeys against single Eimeria infections. Dose-titration studies indicated that diclazuril at dosages of 0.1, 0.5, 1, and 2 ppm was highly effective against the major pathogenic species-E. adenoeides, E. gallopavonis, and E. meleagrimitis-in terms of weight gain and suppression of lesions, abnormal droppings, and oocyst shedding.
Vanparijs
O
O
Janssen Pharmaceutica, Beerse, Belgium.
Hermans
L
L
Van der Flaes
L
L
Marsboom
R
R
D000818:Animals; D003048:Coccidiosis / Q000188:drug therapy / Q000662:veterinary*; D003049:Coccidiostats / Q000008:administration & dosage / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004539:Eimeria / Q000187:drug effects; D005260:Female; D008297:Male; D009570:Nitriles / Q000008:administration & dosage / Q000627:therapeutic use*; D011201:Poultry Diseases / Q000188:drug therapy*; D013045:Species Specificity; D014227:Triazines / Q000008:administration & dosage / Q000627:therapeutic use*; D014422:Turkeys / Q000469:parasitology*
D003049:Coccidiostats; D009570:Nitriles; D014227:Triazines; C057884:diclazuril