Immunocytochemical localization of GABA in neurons projecting to the ventrolateral nucleus of the solitary tract.
To determine the origin of gamma-aminobutyric acidergic (GABAergic) input to the ventrolateral solitary tract nucleus (vlnTS), we used a double-labeling procedure for retrogradely transported horseradish peroxidase (HRP) and the immunocytochemical localization of GABA. Following HRP injections into the vlnTS, double-labeled neurons were found within the Bötzinger Complex. We conclude that these double-labeled cells are the inhibitory Bötzinger neurons and that GABA is a likely transmitter in this respiratory nucleus.
Department of Physiology and Biophysics, University of Washington School of Medicine, Seattle 98195.
C A
CA
Livingston
A J
AJ
Berger
D000818:Animals; D002415:Cats; D006735:Horseradish Peroxidase; D007150:Immunohistochemistry; D008526:Medulla Oblongata / Q000166:cytology / Q000378:metabolism*; D009434:Neural Pathways / Q000033:anatomy & histology / Q000378:metabolism; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D005680:gamma-Aminobutyric Acid; D006735:Horseradish Peroxidase