[Experience in using minipress in essential hypertension].
Investigation of the hypotensive action of minipress, a drug belonging to the group of selective blockers of alpha 1-adrenoreceptors, shows its efficacy in 56.3 percent of patients with stage II essential hypertension. The side-effects were recorded in 16.6 percent of the patients. It is noted that application of minipress at a mean daily dose of 3.4 ml for a long time reduces the total peripheral vascular resistance without inducing any substantial changes in the stroke volume of the heart or in the pulse rate. At the same time minipress produces a beneficial effect on the microcirculatory blood flow.
S G
SG
Ivanov
F V
FV
Solov'eva
V V
VV
Smirnov
L E
LE
Kovalenko
A K
AK
Narynskiĭ
D000328:Adult; D000368:Aged; D004903:Erythrocyte Aggregation / Q000187:drug effects; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011224:Prazosin / Q000009:adverse effects / Q000627:therapeutic use*; D011674:Pulse / Q000187:drug effects; D013318:Stroke Volume / Q000187:drug effects
D011224:Prazosin
Opyt primeneniia minipressa pri gipertonicheskoĭ bolezni.