Neurogenic fibrosarcoma following radiation therapy for seminoma.
We report a case of radiation-induced neurogenic fibrosarcoma that developed in a patient who received radiation therapy for seminoma. The sarcoma developed within the irradiated field after a latency period of nineteen years. Although the occurrence of a secondary neoplasm is unusual, this possibility should be included in the differential diagnosis of patients who present with tumor growth after a long interval following radiation therapy.
O'Brien
W M
WM
Department of Urology, Georgetown University Hospital, Washington, D.C.
Abbondanzo
S L
SL
Chun
B K
BK
Manz
H J
HJ
Maxted
W C
WC
D000328:Adult; D012734:Disorders of Sex Development / Q000150:complications; D004407:Dysgerminoma / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D009455:Neurofibroma / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects*; D012186:Retroperitoneal Neoplasms / Q000209:etiology*; D013736:Testicular Neoplasms / Q000532:radiotherapy*; D013997:Time Factors