Peroxidation of linoleic acid induced by interaction with haemoglobin and hydrogen peroxide.
Peroxidation of linoleic acid was found to be induced by interaction with haemoglobin and hydrogen peroxide. The peroxidation of linoleic acid induced by this interaction was inhibited by desferrioxamine, ethylenediaminetetraacetic acid or alpha-tocopherol, and poorly by catalase. However, it was accelerated by ascorbic acid.
Toda
S
S
Department of Pharmaceutical Science, Kansai Shinkya Medical College, Osaka, Japan.
Ohnishi
M
M
Kimura
M
M
Nakashima
K
K
Iwahashi
H
H
Kido
R
R
D006454:Hemoglobins / Q000494:pharmacology*; D006861:Hydrogen Peroxide / Q000494:pharmacology*; D019787:Linoleic Acid; D008041:Linoleic Acids / Q000378:metabolism*; D015227:Lipid Peroxidation / Q000187:drug effects*; D013858:Thiobarbiturates
D006454:Hemoglobins; D008041:Linoleic Acids; D013858:Thiobarbiturates; D019787:Linoleic Acid; D006861:Hydrogen Peroxide; C029684:thiobarbituric acid