title: [Studies on the chemical constituents of the root of Desmos cochinchinensis Lour].
abstract: Desmos cochinchinensis as a folk medicine is used for treatment of malaria in China. Pharmacological studies showed that the petroleum ether extract of the root of the plant exhibited anti-malarial activity. Three flavonoids were isolated from this extract, of which two were identified as lawinal and isounonal. Compound III is a new flavanol. On the basis of spectroscopic analyses (UV, IR, MS, 1HNMR, 13CNMR and X-RD) the structure was established as 4,7-dihydroxyl-5-methoxyl-6-methyl-8-formyl-flavan. I and II were found from this plant for the first time.
authors: S X
authors: SX
authors: Liao
authors: G Y
authors: GY
authors: Han
authors: Y R
authors: YR
authors: Zhang
authors: Q T
authors: QT
authors: Zheng
authors: C H
authors: CH
authors: He
mesh_terms: D000962:Antimalarials; D055598:Chemical Phenomena; D002621:Chemistry; D004365:Drugs, Chinese Herbal / Q000032:analysis*; D005419:Flavonoids / Q000302:isolation & purification*
chemical_list: D000962:Antimalarials; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; C061425:4,7-dihydroxy-5-methoxy-6-methyl-8-formylflavan; C061398:lawinal; C061424:isounonal