Myasthenia gravis and insulin-dependent diabetes mellitus in two adolescents.
Insulin-dependent diabetes mellitus (IDDM) has rarely, if ever, been reported to be an autoimmune disease associated with myasthenia gravis (MG). Two Chinese patients, one of whom was successfully treated with cyclosporin A (CyA) are reported, with discussion of pathophysiologic mechanisms involved and rationale for the treatment used.
Kuo
C C
CC
Department of Neurology, College of Medicine, National Taiwan University, Taipei, Republic of China.
Chiu
H C
HC
Lin
B J
BJ
D000293:Adolescent; D002648:Child; D003524:Cyclosporins / Q000627:therapeutic use; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000276:immunology / Q000628:therapy; D006684:HLA-DR Antigens; D059810:HLA-DR Serological Subtypes; D006801:Humans; D008297:Male; D009157:Myasthenia Gravis / Q000150:complications* / Q000276:immunology / Q000628:therapy
D003524:Cyclosporins; D006684:HLA-DR Antigens; D059810:HLA-DR Serological Subtypes; C038988:HLA-DR9 antigen