title: [Endocarditis of a natural valve caused by coagulase-negative staphylococci].
abstract: Eleven patients with endocarditis of a natural valve due to coagulase-negative staphylococci are reported. Nine had some underlying heart disease. The course was subacute in seven and acute (two weeks or less) in the remaining four. All patients developed complications: heart failure in nine, arterial emboli in eight, atrioventricular conduction disorders in four, development of paravalvular and/or myocardial abscesses in four, and perforation or rupture of valve leaflets in four. Eight patients were cured, seven of them requiring surgical treatment. Three of the isolated coagulase-negative staphylococci strains were methicillin-resistant; two of them caused community-acquired endocarditis. Natural valve endocarditis due to coagulase-negative staphylococci usually has a subacute course with a tendency to develop severe complications. This makes surgical therapy necessary in a sizeable number of patients.
authors: J M
authors: JM
authors: Aguado García
authors: M L
authors: ML
authors: Fernández Guerrero
authors: J A
authors: JA
authors: Riancho Moral
authors: R
authors: R
authors: Martín Durán
authors: A
authors: A
authors: Ochoteco
mesh_terms: D000328:Adult; D000368:Aged; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D005260:Female; D006349:Heart Valve Diseases / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*
vernacular_title: Endocarditis sobre válvula nativa por estafilococo coagulasa negativo.