title: UCHL1-positive extranodal lymphoma resembling multiple lymphomatous polyposis of the gastrointestinal tract.
abstract: Histopathologic and immunohistochemical studies were done on paraffin sections from a patient with alimentary tract lymphoma resembling multiple lymphomatous polyposis of the gastrointestinal tract (MLP). Diffuse, but not follicular, proliferation of medium-sized lymphoid cells was noted in the polypoid lesions of the alimentary tract, peripancreatic lymph nodes, spleen, liver, and bone marrow. These cells possessed a T-cell-related antigen (UCHL1), but were negative for the B-cell-related and myeloid cell-related antigens examined. Because neoplastic cells in MLP are usually of B-cell origin, the current case will provide important information on the relation between phenotypes and morphologic patterns of proliferation.
authors: Department of Laboratory Medicine, Wakayama Medical School, Japan.
authors: H
authors: H
authors: Nakamine
authors: H
authors: H
authors: Sakamoto
authors: T
authors: T
authors: Tanaka
authors: N
authors: N
authors: Nakashima
authors: T
authors: T
authors: Takenaka
authors: J
authors: J
authors: Maeda
mesh_terms: D000368:Aged; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis; D004067:Digestive System Neoplasms / Q000032:analysis / Q000473:pathology*; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000032:analysis / Q000473:pathology*; D008297:Male; D011127:Polyps / Q000473:pathology*; D013601:T-Lymphocytes / Q000032:analysis / Q000473:pathology
chemical_list: D000945:Antigens, Differentiation, T-Lymphocyte