title: UK-69,753, a novel member of the efrotomycin family of antibiotics. I. Taxonomy of the producing organism, fermentation and isolation.
abstract: UK-69,753 is a novel antibiotic structurally related to efrotomycin and factumycin, produced by a new strain of Amycolatopsis orientalis (ATCC 53550). The antibiotic potency in the fermentation broth was monitored by HPLC with diode array detection. A six tube counter current distribution was used to purify UK-69,753.
authors: Central Research Division, Pfizer Ltd., Kent, England.
authors: M S
authors: MS
authors: Pacey
authors: M R
authors: MR
authors: Jefson
authors: L H
authors: LH
authors: Huang
authors: W P
authors: WP
authors: Cullen
authors: H
authors: H
authors: Maeda
authors: J
authors: J
authors: Tone
authors: S
authors: S
authors: Nishiyama
authors: K
authors: K
authors: Kaneda
authors: M
authors: M
authors: Ishiguro
mesh_terms: D000192:Actinomycetales / Q000145:classification / Q000378:metabolism*; D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000302:isolation & purification*; D055598:Chemical Phenomena; D002621:Chemistry; D005285:Fermentation; D011714:Pyrans / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D011714:Pyrans; C058298:UK 69753