Human diabetic serum does not stimulate bovine retinal endothelial cell growth in culture.
Bovine retinal microvascular endothelial cells were cultured with serum from nondiabetic controls, patients with background, preproliferative, proliferative and inactive (treated) proliferative diabetic retinopathy. Using Coomassie Blue to measure cellular protein, we found no significant increase in retinal endothelial cell growth with serum from patients with preproliferative or proliferative retinopathy.
Kinshuck
D
D
Department of Medicine, Royal Postgraduate Medical School, London, UK.
Brooks
R A
RA
Kohner
E M
EM
D000818:Animals; D002417:Cattle; D002455:Cell Division; D002478:Cells, Cultured; D003470:Culture Media; D003930:Diabetic Retinopathy / Q000097:blood*; D004730:Endothelium, Vascular / Q000166:cytology*; D005346:Fibroblast Growth Factors / Q000378:metabolism; D005353:Fibronectins / Q000378:metabolism; D006801:Humans; D011994:Recombinant Proteins; D012171:Retinal Vessels / Q000502:physiology*; D013997:Time Factors
D003470:Culture Media; D005353:Fibronectins; D011994:Recombinant Proteins; D005346:Fibroblast Growth Factors