title: Effect of amine fluoride/stannous fluoride-containing toothpaste and mouthrinsings on dental plaque, gingivitis, plaque and enamel F-accumulation.
abstract: The aim of the study was to assess the effect of an amine fluoride/stannous fluoride toothpaste and mouthwash on dental plaque and gingivitis, plaque F- accumulation, F- content and acid solubility of dental enamel. Participants in the 12-week double-blind study were 92 schoolchildren, with a mean age of 12.4 years, randomly distributed to four groups: (1) AmF/SnF2 toothpaste, (2) placebo toothpaste, (3) AmF/SnF2 toothpaste plus AmF/SnF2 mouthwash, (4) placebo toothpaste plus AmF/SnF2 mouthwash. Analyzing the results, the mean values of dental plaque (Silness-Löe index) and of the sulcus bleeding index decreased statistically significantly in all groups except the placebo toothpaste users. Plaque F- and enamel F- content increased considerably only in the two groups using the AmF/SnF2 toothpaste. A decrease in acid solubility was significant only in the group of both test toothpaste and test mouthwash users. Thus the clinical efficacy of the tested AmF/SnF2 toothpaste might be increased by the combined use of mouthrinsings containing the same substances.
authors: Department of Conservative Dentistry, Faculty of Dentistry, Semmelweis Medical University, Budapest, Hungary.
authors: J
authors: J
authors: Bánóczy
authors: J
authors: J
authors: Szöke
authors: P
authors: P
authors: Kertész
authors: Z
authors: Z
authors: Töth
authors: P
authors: P
authors: Zimmermann
authors: Z
authors: Z
authors: Gintner
mesh_terms: D000588:Amines / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D003743:Dental Enamel / Q000737:chemistry*; D003747:Dental Enamel Solubility / Q000187:drug effects*; D003773:Dental Plaque / Q000737:chemistry / Q000517:prevention & control*; D003802:Dentifrices; D004338:Drug Combinations; D005459:Fluorides / Q000008:administration & dosage / Q000032:analysis / Q000627:therapeutic use*; D005891:Gingivitis / Q000517:prevention & control*; D006801:Humans; D009067:Mouthwashes; D014002:Tin Fluorides / Q000008:administration & dosage / Q000627:therapeutic use*; D014100:Toothpastes
chemical_list: D000588:Amines; D003802:Dentifrices; D004338:Drug Combinations; D009067:Mouthwashes; D014002:Tin Fluorides; D014100:Toothpastes; D005459:Fluorides; C008703:oleylamine