Selective incorporation of 2-deoxyglucose into the developing spinal cord in vitro in response to target tissue and substratum.
Differential uptake of [3H]deoxyglucose by larval frog spinal cord explants in vitro has demonstrated that metabolic activity is localized to the lateral motor columns in response to co-cultured target tissue or a neurite-promoting substratum. Autoradiographic data suggest that chemokinesis may be an integral component of motor neuron growth activation.
Muhlach
W L
WL
Department of Biological Sciences, University of Illinois, Chicago 60680.
Pollack
E D
ED
D000818:Animals; D002470:Cell Survival; D003837:Deoxy Sugars / Q000378:metabolism*; D003847:Deoxyglucose / Q000378:metabolism*; D009046:Motor Neurons / Q000378:metabolism; D011894:Rana pipiens; D013116:Spinal Cord / Q000166:cytology / Q000254:growth & development*
D003837:Deoxy Sugars; D003847:Deoxyglucose