Dye injection confirms the electrophysiological identification of regenerating muscle fibres in the rat.
Microelectrodes were inserted at random into superficial fibres in rat regenerating soleus muscles. The fibres from which recordings of electrical properties were made were marked using the dye Lucifer Yellow CH and then processed for histological studies. It was shown that the microelectrodes had sampled small regenerating muscle fibres, and that random penetration does not select for any undamaged fibres that may be present.
Grubb
B D
BD
Muscular Dystrophy Group Research Laboratories, Newcastle General Hospital.
Harris
J B
JB
D000818:Animals; D004546:Elapid Venoms; D004594:Electrophysiology; D005260:Female; D005404:Fixatives; D007267:Injections; D007546:Isoquinolines; D008564:Membrane Potentials; D008839:Microelectrodes; D008856:Microscopy, Fluorescence; D009132:Muscles / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D012038:Regeneration; D013997:Time Factors
D004546:Elapid Venoms; D005404:Fixatives; D007546:Isoquinolines; C005082:notexin; C017475:lucifer yellow