[Changes in lung compliance and maximal expiratory flow-volume curves when breathing air and an He-O2 mixture in light smokers].
Lung compliance (CL) and maximal expiratory flow-volume curves (MEFV) breathing air and helium-oxygen mixture in 34 healthy nonsmokers and 55 young light smokers were studied. The difference of FEV1%, PEFR and MMEF between smokers and nonsmokers were statistically significant. The results of small airway function tests were compared and analysed. In the 55 smokers, 38(69.1%) showed frequency dependence of dynamic compliance (FDC), only 5(9.1%) had an abnormal V25/HT and 4(7.3%) showed an abnormal MMEF. of 48 smokers (31.3%) had an abnormal volume of isoflow (VisoV), We concluded that among the small airway function tests FDC is the most sensitive one in light smokers.
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D000328:Adult; D000388:Air; D005540:Forced Expiratory Flow Rates; D006371:Helium / Q000032:analysis; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D008170:Lung Compliance / Q000502:physiology*; D008297:Male; D008449:Maximal Expiratory Flow-Volume Curves; D010100:Oxygen / Q000032:analysis; D012129:Respiratory Function Tests; D012907:Smoking / Q000503:physiopathology*
D006371:Helium; D010100:Oxygen