title: Lymphokine production in patients with Alzheimer's disease.
abstract: The capacity of peripheral blood mononuclear cells (PBMC) isolated from patients with Alzheimer's disease to produce interleukin-1 and -2 (IL-1, IL-2) was compared to that of cells from age-matched controls and young healthy subjects. There was no difference in the production of both interleukins between patients and their age-matched controls. On the other hand, the production of IL-1 by the PBMC of healthy young volunteers was significantly higher than that of the cells from patients and subjects of the other two groups. Although the results indicated a higher production of IL-2 by PBMC from younger individuals, the difference in comparison with the other two groups was not statistically significant.
authors: Research Laboratory, Hasharon Hospital, Petah-Tiqva, Israel.
authors: H
authors: H
authors: Bessler
authors: P
authors: P
authors: Sirota
authors: J
authors: J
authors: Hart
authors: M
authors: M
authors: Djaldetti
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000097:blood*; D006801:Humans; D007375:Interleukin-1 / Q000096:biosynthesis*; D007376:Interleukin-2 / Q000096:biosynthesis*; D007963:Leukocytes, Mononuclear / Q000378:metabolism; D008875:Middle Aged
chemical_list: D007375:Interleukin-1; D007376:Interleukin-2