[Radiotherapy of stomach cancer under conditions of severe exogenous hypoxia (8% O2)].
Irradiation of 116 stomach cancer patients was performed under the conditions of hypoxia caused by the inhalation of a gaseous mixture containing (8 +/- 0.5%) O2; irradiation of 108 patients was performed in the air. The method of hypoxic radiotherapy of stomach cancer is described. The authors present some data on radiation reactions, tumor regression, the condition of tumorous and normal tissue after radiotherapy under the conditions of hypoxia which permitted an increase in a tumor radiation dose and a decrease in the number and gravity of radiation reactions. The above method of large field preoperative irradiation made it possible to improve short-term results of combined therapy of stomach cancer patients.
Khvorostenko
M I
MI
D000230:Adenocarcinoma / Q000532:radiotherapy*; D000280:Administration, Inhalation; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000008:administration & dosage / Q000502:physiology*; D011832:Radiation Injuries / Q000517:prevention & control*; D013274:Stomach Neoplasms / Q000532:radiotherapy*
D010100:Oxygen
Luchevaia terapiia raka zheludka v usloviiakh "zhestkoĭ" ékzogennoĭ gipoksii (8% O2).