[Regulatory effects of opioid peptides on bone marrow hematopoiesis in stress].
It was shown that inhibition of bone marrow hyperplasia disappear due to injection of leu-enkephalin and dalargin as well as the increase of plasma leu-enkephalin by means of D-phenylalanine on the immobilized mice. The effect of enkephalin on hematopoietic precursor cells may be realized by inhibition of T-lymphocytes migration to bone marrow. Besides, direct specific influence of dalargin on myelokaryocytes is observed.
Gol'dberg
E D
ED
Dygaĭ
A M
AM
Zakharova
O Iu
OIu
Shakhov
V P
VP
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects*; D004723:Endorphins / Q000494:pharmacology*; D004743:Enkephalin, Leucine / Q000031:analogs & derivatives / Q000494:pharmacology; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives*; D006410:Hematopoiesis / Q000187:drug effects*; D006412:Hematopoietic Stem Cells / Q000187:drug effects; D007103:Immobilization; D008297:Male; D051379:Mice; D013312:Stress, Physiological / Q000209:etiology / Q000503:physiopathology*; D013565:Sympatholytics / Q000494:pharmacology
D004723:Endorphins; D013565:Sympatholytics; D004743:Enkephalin, Leucine; D016308:Enkephalin, Leucine-2-Alanine; C040996:enkephalin-Leu, Ala(2)-Arg(6)-
Reguliatornye vliianiia opioidnykh peptidov na kostnomozgovoe krovetvorenie pri stresse.