Solitary increased tibial uptake of 99mTc-diphosphonate unmasking pancreatic tumor-related medullary fat necrosis.
Pancreatic inflammation and tumors can induce various systemic lesions of steatonecrosis. We report here the case of a 73-year-old woman presenting a painful left leg. Roentgenograms and tomograms of the left tibia were normal. Radionuclide bone scan showed diffuse increased uptake in the whole tibia and a CT scan of the same region demonstrated an unusual pattern of bone tumor. Tibial biopsy revealed intra medullary steatonecrosis and led to the discovery of a pancreatic carcinoma.
Paycha
F
F
Service de Médecine Nucléaire, C.H.U. Xavier Bichat, Paris, France.
Russ
G
G
Bellivet
C
C
Vulpillat
M
M
D000230:Adenocarcinoma / Q000150:complications; D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D005218:Fat Necrosis / Q000209:etiology*; D005260:Female; D006801:Humans; D009336:Necrosis / Q000209:etiology*; D010190:Pancreatic Neoplasms / Q000150:complications*; D013669:Technetium Tc 99m Medronate / Q000493:pharmacokinetics*; D013977:Tibia / Q000378:metabolism* / Q000473:pathology
D013669:Technetium Tc 99m Medronate