Biosynthetic preparation of labeled 4,4-dimethylzymosterol.
Labeled 4,4-dimethyl-5 alpha -cholesta-8,24-dien-3 beta-ol (4,4-dimethylzymosterol) was prepared by incubating labeled mevalonate with rat liver extracts in the presence of arsenite and lanosterol.
Maitra
U S
US
Department of Biochemistry, College of Physicians & Surgeons, Columbia University, New York, NY.
Mohan
V P
VP
Sprinson
D B
DB
D000818:Animals; D001151:Arsenic / Q000494:pharmacology; D018053:Arsenites; D002775:Cholestadienols / Q000378:metabolism*; D007810:Lanosterol / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D008798:Mevalonic Acid / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D014316:Tritium
D018053:Arsenites; D002775:Cholestadienols; D014316:Tritium; D007810:Lanosterol; C013499:4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol; C015001:arsenite; D001151:Arsenic; D008798:Mevalonic Acid