Prediction of neurological damage after cardiopulmonary bypass surgery. Use of the cerebral function analysing monitor.
Sixty-five patients who had coronary artery graft surgery were subjected to detailed neuropsychometric assessment before operation and twice again within 7 days after operation. They were monitored continuously with a cerebral function analysing monitor during the operation. The results of the peroperative cerebral monitoring were compared on completion of the study with the neuropsychometric assessments. Seventy-six percent of the patients with a significant neuropsychometric deficit after operation also showed significant peroperative changes on the analysing monitor; the majority occurred immediately after the start of perfusion. Twenty-eight patients failed to demonstrate any evidence of neuropsychometric deficit and six (21%) of these also showed significant peroperative changes. All patients whose traces demonstrated more than one significant change during the peroperative course had a significant neuropsychometric deficit afterwards.
Nevin
M
M
Department of Cardiothoracic Surgery, St George's Hospital, London.
Colchester
A C
AC
Adams
S
S
Pepper
J R
JR
D001921:Brain / Q000503:physiopathology*; D001927:Brain Diseases / Q000209:etiology* / Q000503:physiopathology; D002315:Cardiopulmonary Bypass; D004569:Electroencephalography / Q000295:instrumentation*; D006801:Humans; D009483:Neuropsychological Tests / Q000379:methods; D011183:Postoperative Complications / Q000209:etiology* / Q000503:physiopathology; D011336:Probability; D011594:Psychometrics