title: Arthritis associated with adjuvant mycobacterial treatment for carcinoma of the bladder.
abstract: A patient who developed an inflammatory polyarthritis following intravesical administration of bacillus Calmette-Guérin (BCG) used in the treatment of bladder cancer is described. An inflammatory synovitis comprising predominantly T lymphocytes was demonstrated on synovial biopsy. The synovitis resolved spontaneously within 14 days in this 'human model' of adjuvant arthritis.
authors: Department of Immunology of Rheumatic Disease, Charing Cross Hospital, London.
authors: R A
authors: RA
authors: Hughes
authors: S A
authors: SA
authors: Allard
authors: R N
authors: RN
authors: Maini
mesh_terms: D000283:Administration, Intravesical; D000368:Aged; D000369:Aged, 80 and over; D001168:Arthritis / Q000209:etiology* / Q000473:pathology; D001169:Arthritis, Experimental / Q000209:etiology; D001500:BCG Vaccine / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D013582:Synovial Fluid / Q000166:cytology; D013585:Synovitis / Q000209:etiology / Q000473:pathology; D013601:T-Lymphocytes; D001749:Urinary Bladder Neoplasms / Q000628:therapy*
chemical_list: D001500:BCG Vaccine