title: [Experimental visualization of human colon cancer using 131I-antibodies to intestinal beta 1 MA antigen].
abstract: 131I-antibodies to human beta 1 colonic antigen was administered i.v. to nude mice with transplanted human colon carcinoma. Injections were followed by mouse whole-body investigation with the help of gamma-camera and scanner. The distribution of radioactivity in murine tissues was investigated with a gamma-counter. Sharp images of tumor were obtained with the help of the gamma-camera and scanner. The results of visualization were in accord with radioimmunometric data. A conclusion was made of effective visualization of human colon carcinoma transplanted to nude mice using iodinated antibodies to specific beta 1 MA epithelial colonic antigen.
authors: L M
authors: LM
authors: Fidler
authors: S K
authors: SK
authors: Aleksander
authors: V B
authors: VB
authors: Mit'kov
authors: K K
authors: KK
authors: Pugachev
authors: Iu V
authors: IuV
authors: Lukin
authors: G I
authors: GI
authors: Avdeev
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm / Q000276:immunology*; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging* / Q000276:immunology; D006801:Humans; D007457:Iodine Radioisotopes; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation; D011877:Radionuclide Imaging; D014183:Transplantation, Heterologous
chemical_list: D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D007457:Iodine Radioisotopes
vernacular_title: Vizualizatsiia kartsinom tolstoĭ kishki cheloveka s pomoshch'iu 131I-antitel k kishechnomu antigenu beta 1 MA v éksperimente.