[Effect of erythropifadin on the morphofunctional characteristics of donor blood preserved for a long time].
Adenine- and riboxine-containing erythropifaden has been studied for possibility to be used for restoring a functional value of erythrocytes in conserved donor blood stored for 35-49 days. Energy supply and oxygen transport function of erythrocytes are shown to get normal and their morphological composition--to get considerably improved. Besides, osmotic resistance and deformability of erythrocytes insignificantly change while concentration of riboxine in blood and that of substances with average molecular mass remain considerably high. One of the ways to remove the above shortcomings is application of hemosorbents.
Belkin
A L
AL
Pendrak
K A
KA
Povzhitkova
M S
MS
Petrenko
S V
SV
Kovalishin
Ia F
IaF
D000225:Adenine / Q000494:pharmacology*; D001774:Blood Chemical Analysis; D001782:Blood Donors; D001793:Blood Preservation; D004338:Drug Combinations / Q000494:pharmacology; D004907:Erythrocyte Deformability / Q000187:drug effects; D004912:Erythrocytes / Q000166:cytology / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D007288:Inosine / Q000494:pharmacology*; D009996:Osmotic Fragility / Q000187:drug effects; D012996:Solutions; D013997:Time Factors
D004338:Drug Combinations; D012996:Solutions; C061428:erythropifaden; D007288:Inosine; D000225:Adenine
Vliianie éritropifadena na morfofunktsional'nye kharakteristiki dlitel'no khranimoĭ donorskoĭ krovi.