The use of 2.5% natamycin, as orally administered drops, in the treatment of fungal infections of the oral cavity in children with chronic blood diseases.
A total of 34 children with oral candidiasis were treated with 2.5% natamycin in the form of orally administered drops; 6-20 drops applied to oral lesions four times daily for up to 8 weeks. A total cure was achieved in 28 (82.3%) cases. No side-effects were observed. This preparation was an effective treatment for Candida albicans infections in children with blood diseases, and was well tolerated.
Rokicka-Milewska
R
R
Department of Pediatric Oncology and Haemorrhagic Diseases, Institute of Paediatrics, Warsaw, Poland.
Derulska
D
D
Lipnicki
D
D
Skrobowska-Woźniak
A
A
Moszczeńska
A
A
D000208:Acute Disease; D000284:Administration, Oral; D000293:Adolescent; D000741:Anemia, Aplastic / Q000150:complications; D002180:Candidiasis, Oral / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D006402:Hematologic Diseases / Q000150:complications*; D006801:Humans; D007223:Infant; D007938:Leukemia / Q000150:complications; D010866:Natamycin / Q000008:administration & dosage / Q000627:therapeutic use*; D013921:Thrombocytopenia / Q000150:complications
D010866:Natamycin