[Clinical evaluation of diacerein in the treatment of osteoarthrosis].
Diacereine was given to 40 patients whose age ranged from 45 to 87 years; they were suffering from radiologically controlled osteoarthrosis. The oral dosage was 50 mg twice a day and it was given for 4 weeks. The results were classified good in 78% of the patients. Improvement become usually manifest after 2 weeks from starting treatment. Diarrhoea was the only collateral effect in 15% of the cases. In conclusion, Diacereine gives positive effects on osteoarthrosis treatment.
Mazzaro
C
C
U.S.L. n. 11 Pordenonese, Ospedale Civile, Pordenone.
Bocchieri
E
E
Tesolin
G F
GF
Ventre
L
L
Romagnoli
A
A
D000368:Aged; D000369:Aged, 80 and over; D000880:Anthraquinones / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D003967:Diarrhea / Q000139:chemically induced; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy*; D013997:Time Factors
D000880:Anthraquinones; D000894:Anti-Inflammatory Agents, Non-Steroidal; C025292:diacerein
Valutazione clinica della diacereina nel trattamento dell'osteoartrosi.