title: Pregnancies in reliable pill takers.
abstract: This study is an extension of a previous study on oral contraceptive pill method failure in reliable pill takers. It documents 137 cases which presented during the 3 year period from December 1985 to December 1988. The most important new finding is that smoking is a significant risk factor in failure on the combined pill (67% were smokers, n = 118), but not on the progestagen-only pill, although the numbers in the latter group were small (n = 19). Diarrhoea and/or vomiting (46%) and drug interactions (33%) are confirmed as important predisposing factors. Systemic illness and/or severe psychological stress may also affect pill utilisation and such factors were found in 47%. Menstrual disturbances were found in 32% of women on the combined pill and 68% of these were smokers. Multiple factors were present in most cases (79%). Repeat failures occurred in 25%.
authors: Parkview Clinic, Wellington Hospital.
authors: M J
authors: MJ
authors: Sparrow
mesh_terms: D000293:Adolescent; D000328:Adult; D003276:Contraceptives, Oral / Q000009:adverse effects; D003967:Diarrhea / Q000139:chemically induced; D004347:Drug Interactions; D005260:Female; D006801:Humans; D008599:Menstruation Disturbances / Q000139:chemically induced; D010349:Patient Compliance; D011247:Pregnancy; D014839:Vomiting / Q000139:chemically induced
chemical_list: D003276:Contraceptives, Oral