title: Borna disease, a progressive meningoencephalomyelitis as a model for CD4+ T cell-mediated immunopathology in the brain.
abstract: A homogeneous T cell line NM1 with Borna disease (BD) virus reactivity could be established. The NM1 cells have been characterized as CD4+ T cells. Adoptive transfer revealed that this MHC class II-restricted immune cell is responsible for the immunopathological effect leading to BD, a progressive meningoencephalomyelitis.
authors: Institut für Virologie, Justus-Liebig-Universität Giessen, Federal Republic of Germany.
authors: J A
authors: JA
authors: Richt
authors: L
authors: L
authors: Stitz
authors: H
authors: H
authors: Wekerle
authors: R
authors: R
authors: Rott
mesh_terms: D000818:Animals; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis*; D001890:Borna Disease / Q000276:immunology*; D001891:Borna disease virus / Q000276:immunology; D004195:Disease Models, Animal; D008590:Meningoencephalitis / Q000276:immunology*; D051381:Rats; D011917:Rats, Inbred Lew; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D000945:Antigens, Differentiation, T-Lymphocyte