title: Cerebral anoxic attacks in sleep apnea syndrome.
abstract: In a 52-year-old man who presented with an obstructive sleep apnea (OSAS) syndrome, we observed cerebral anoxic attacks during rapid eye movement (REM) sleep. Polysomnography showed that the attacks were due to severe hypoxia provoked by apneas lasting up to 220 s. Electroencephalogram (EEG) and clinical features clearly differentiate cerebral anoxic attacks from epileptic seizures. The length of apneas in our patient is very unusual, indicating an impairment of the mechanism terminating apneas. The cause of this impairment is unknown. However, this case report documents a possible pathogenetic mechanism other than heart arrhythmias responsible for sudden death or coma arising during sleep.
authors: Institute of Neurology, University of Bologna, Italy.
authors: F
authors: F
authors: Cirignotta
authors: M
authors: M
authors: Zucconi
authors: S
authors: S
authors: Mondini
authors: R
authors: R
authors: Gerardi
authors: E
authors: E
authors: Lugaresi
mesh_terms: D001143:Arousal / Q000502:physiology; D002540:Cerebral Cortex / Q000503:physiopathology; D004569:Electroencephalography; D006801:Humans; D002534:Hypoxia, Brain / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D012891:Sleep Apnea Syndromes / Q000503:physiopathology*; D012894:Sleep Stages / Q000502:physiology*; D012895:Sleep, REM / Q000502:physiology; D013035:Spasm / Q000503:physiopathology; D013826:Theta Rhythm; D014851:Wakefulness / Q000502:physiology