[Differential diagnosis of the rejection crisis and toxic and immune-induced nephropathy].
The work is based on the analysis of materials concerning 26 patients with transplanted allogeneic kidneys. All the patients received immunodepressive therapy with a combination of prednisolone and sandimmune. The posttransplantation period was complicated by sandimmune nephropathy in 11 and by a rejection crisis in 15 patients. The following tests were used in the differential diagnosis of these two complications: clinical (firmness of the allogeneic kidney determined by palpation, arterial hypertension, hyperthermia), laboratory (level of creatinine in blood and its clearance, potassium and sodium in urine), and instrumental-functional (ultrasonic examination, electrothermometry, rheography). With the use of these tests, nephrotoxicity of sandimmune origin and rejection crisis were differentiated successfully in all cases.
Belorusov
O S
OS
Goriaĭnov
V A
VA
Chemisova
G G
GG
Morozova
M M
MM
D000293:Adolescent; D000328:Adult; D003524:Cyclosporins / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005260:Female; D006084:Graft Rejection; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D007674:Kidney Diseases / Q000139:chemically induced / Q000175:diagnosis* / Q000601:surgery; D016030:Kidney Transplantation / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis*
D003524:Cyclosporins; D007166:Immunosuppressive Agents
Differentsia'lnaia diagnostika kriza ottorzheniia i toksicheskoĭ sandimmunovoĭ nefropatii.