title: Anticentromere antibody positive CREST syndrome associated with polyarthritis, renal impairment and mixed cryoglobulinaemia.
abstract: We describe a 63-year-old female who developed the CREST syndrome within two years. Even though she was anticentromere antibody positive, her illness followed a very aggressive course and was associated with severe polyarthritis, renal impairment, hypocomplementaemia and mixed cryoglobulinaemia.
authors: Department of Rheumatology, University Hospital of Wales, Cardiff, UK.
authors: H G
authors: HG
authors: Shetty
authors: M M
authors: MM
authors: O'Sullivan
authors: N
authors: N
authors: Amos
authors: B D
authors: BD
authors: Williams
mesh_terms: D000208:Acute Disease; D000974:Antibodies, Antinuclear / Q000032:analysis*; D001168:Arthritis / Q000150:complications* / Q000276:immunology; D002114:Calcinosis / Q000276:immunology*; D002503:Centromere / Q000276:immunology*; D002875:Chromosomes / Q000276:immunology*; D003449:Cryoglobulinemia / Q000150:complications* / Q000276:immunology; D015154:Esophageal Motility Disorders / Q000276:immunology*; D005260:Female; D006227:Hand Deformities, Acquired / Q000276:immunology*; D006801:Humans; D008875:Middle Aged; D011928:Raynaud Disease / Q000276:immunology*; D013577:Syndrome; D013684:Telangiectasis / Q000276:immunology*
chemical_list: D000974:Antibodies, Antinuclear