Frequency-specific auditory brainstem response analysis of young normal, aged normal and aged alcohol-addicted rats.
Normative data for frequency-specific (+/- 100 Hz) auditory brainstem response (ABR) thresholds were determined in 60 normal healthy 3-month-old, 5 normal 22-month-old and 6 alcohol-addicted 22-month-old Sprague Dawley rats. The highest degree of auditory sensitivity was in the range of 12-20 kHz. These frequencies showed significant mean differences between the 3-month-old and the old normal rats. In contrast, alcohol-addicted old rats did not reveal any significant threshold changes as compared with either normal old or 3-month-old rats.
Anniko
M
M
Department of Oto-Rhino-Laryngology and Head and Neck Surgery, University of Umeå, Sweden.
Hellström
S
S
Wahlström
G
G
D000375:Aging; D000437:Alcoholism / Q000503:physiopathology*; D000818:Animals; D001308:Auditory Perceptual Disorders / Q000503:physiopathology; D001309:Auditory Threshold / Q000502:physiology*; D001933:Brain Stem / Q000503:physiopathology*; D007758:Ear, Inner / Q000503:physiopathology*; D004594:Electrophysiology; D051381:Rats; D011919:Rats, Inbred Strains