title: The effect of acoustic cavitation on the contraction force and membrane potential of rat papillary muscle.
abstract: In experiments on isolated rat papillary muscles an acoustic cavitation induced by continuous wave focused ultrasound (543 kHz with intensity up to 3 W/cm2) was found to result in reversible membrane depolarization by 54.0 +/- 1.4 mV (n = 5), loss of excitability and rise in resting tension up to 53.1 +/- 4.3% (n = 15) of contractile response in the control. It was supposed that the rapid recovery of excitability (69.3 +/- 10.3 s, n = 15) might be a result of Ca2+ pump activation and/or alterations of intercellular coupling when cavitation ends.
authors: Institute of Experimental Cardiology, USSR Cardiology Research Center, Moscow.
authors: S I
authors: SI
authors: Zakharov
authors: Bogdanov KYu
authors: L V
authors: LV
authors: Rosenshtraukh
authors: L R
authors: LR
authors: Gavrilov
authors: V P
authors: VP
authors: Yushin
mesh_terms: D000818:Animals; D005260:Female; D008297:Male; D008564:Membrane Potentials; D009200:Myocardial Contraction; D010210:Papillary Muscles / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D014465:Ultrasonics