[Urban air pollution and respiratory health: the stakes involved and methods of approach].
During the past twenty years, evidence has been accumulating of a significant association between concentration levels of urban air pollutants and acute or chronic respiratory diseases, including lung cancer. Identification of the responsible atmospheric pollutants is necessary for the development of rational air standards and effective control strategies. The main sources of information are experimental animal studies, controlled exposure of human volunteers to specific pollutants at realistic concentrations, and "in vitro" bioassays, concerning genotoxicity and biological effects of toxic gases and particles on the main target cells of the respiratory tract, particularly alveolar macrophages.
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D000208:Acute Disease; D000393:Air Pollutants / Q000633:toxicity*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D012140:Respiratory Tract Diseases / Q000139:chemically induced*; D014504:Urban Health
D000393:Air Pollutants
Pollution atmosphérique urbaine et santé respiratoire: enjeux et modalités d'approche.