title: Open trial of fluoxetine in obsessive-compulsive disorder.
abstract: A 12-week open trial of fluoxetine in 61 obsessive-compulsive disorder patients significantly improved depressive and obsessive-compulsive symptoms. Baseline depression scores were not related to improvement on two obsessive-compulsive scales. The results reinforce the hypothesis of serotonergic abnormalities in obsessive-compulsive disorder.
authors: Harvard Medical School, OCD Clinic and Research Unit, Massachusetts General Hospital, Boston 02114.
authors: M A
authors: MA
authors: Jenike
authors: L
authors: L
authors: Buttolph
authors: L
authors: L
authors: Baer
authors: J
authors: J
authors: Ricciardi
authors: A
authors: A
authors: Holland
mesh_terms: D000328:Adult; D003863:Depression / Q000188:drug therapy; D005260:Female; D005473:Fluoxetine / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy*; D010556:Personality Tests
chemical_list: D005473:Fluoxetine