title: Endogenous candidal endophthalmitis.
abstract: The incidence of systemic mycotic infections, though formerly rare, has increased dramatically over the past two decades. Candida albicans has been recognized as the most common pathogen in endogenous fungal endophthalmitis. Accurate antemortem diagnosis of disseminated candidiasis is made, however, only in a few cases. Ocular findings may often provide the first definitive clue to an underlying mycotic infection. We present four cases of candidal endophthalmitis; in each the ophthalmologist played a major role in the early diagnosis of the underlying systemic infection, allowing specific therapeutic measures to be taken. We also discuss the common predisposing factors, ocular symptoms and findings, clinical course, and response to antifungal therapy.
authors: Department of Ophthalmology, Golda Medical Center, Petach Tikva, Israel.
authors: D
authors: D
authors: Deutsch
authors: S
authors: S
authors: Adler
authors: J
authors: J
authors: Teller
authors: H
authors: H
authors: Savir
mesh_terms: D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D002177:Candidiasis / Q000175:diagnosis / Q000188:drug therapy; D009877:Endophthalmitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D005128:Eye Diseases / Q000473:pathology; D005260:Female; D005437:Flucytosine / Q000627:therapeutic use; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000150:complications; D014605:Uveitis / Q000150:complications; D014792:Visual Acuity; D014822:Vitreous Body / Q000473:pathology*
chemical_list: D000666:Amphotericin B; D005437:Flucytosine