Resistance to serum bactericidal activity distinguishes Brazilian purpuric fever (BPF) case strains of Haemophilus influenzae biogroup aegyptius (H. aegyptius) from non-BPF strains. Brazilian Purpuric Fever Study Group.
We studied the ability of normal human serum to lyse H. influenzae biogroup aegyptius (H. aegyptius) isolates recovered from patients with Brazilian purpuric fever (BPF clone) or non-BPF clone strains. BPF clone isolates, although similar to non-BPF clone isolates with regard to the ability to fix C3 to their surfaces, could be distinguished from non-BPF clone strains by their resistance to lysis in vitro following incubation with normal adult human serum.
Porto
M H
MH
Department of Pediatrics, New York Hospital-Cornell Medical Center, New York 10021.
Noel
G J
GJ
Edelson
P J
PJ
D001770:Blood Bactericidal Activity; D002675:Child, Preschool; D003176:Complement C3 / Q000276:immunology; D003168:Complement Fixation Tests; D003171:Complement Pathway, Classical; D003234:Conjunctivitis, Bacterial / Q000382:microbiology*; D006192:Haemophilus Infections / Q000382:microbiology*; D006193:Haemophilus influenzae / Q000145:classification / Q000276:immunology; D006801:Humans; D011693:Purpura / Q000382:microbiology*; D013045:Species Specificity
D003176:Complement C3