Carcinogenic effects in rat progeny exposed perinatally to radionuclides.
The distribution of two transuranic elements, plutonium and americium, in pregnant rats and in their fetuses, and the carcinogenic effects seen in progeny exposed perinatally are discussed. The appearance of malignant tumours in the liver and skeleton corresponds to the pattern of deposition of these radionuclides in the body.
Moskalev YuI
Institute of Biophysics, Ministry of Health, Moscow, USSR.
Lyaginskaya
A M
AM
Zalikin
G A
GA
Nisimov
P G
PG
Romanova
I B
IB
Korneev YeYu
D000576:Americium / Q000493:pharmacokinetics / Q000633:toxicity*; D000818:Animals; D000831:Animals, Newborn; D005260:Female; D008431:Maternal-Fetal Exchange; D009381:Neoplasms, Radiation-Induced; D011005:Plutonium / Q000493:pharmacokinetics / Q000633:toxicity*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D011919:Rats, Inbred Strains; D014018:Tissue Distribution
D011005:Plutonium; D000576:Americium