title: [Etiologic significance of hereditary deficiency of proteinase alpha1-inhibitor in the formation of respiratory diseases].
abstract: A study was made of the content of protease alpha 1-inhibitor and of the phenotyping of protease alpha 1-inhibitor subtypes in 666 patients with different chronic non-specific pulmonary diseases. It is concluded that pronounced deficiency of protease alpha 1-inhibitor is of importance in the formation of primary emphysema, chronic obstructive bronchitis and bronchial asthma. The clinical characteristics of obstructive pulmonary diseases marked by protease alpha 1-inhibitor deficiency have been investigated.
authors: T E
authors: TE
authors: Gembitskaia
authors: N K
authors: NK
authors: Monakhov
authors: V A
authors: VA
authors: Ignat'ev
authors: T D
authors: TD
authors: Aleĭnikova
authors: M M
authors: MM
authors: Shavlovskiĭ
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006720:Homozygote; D006801:Humans; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D012140:Respiratory Tract Diseases / Q000209:etiology*; D000515:alpha 1-Antitrypsin / Q000235:genetics; D019896:alpha 1-Antitrypsin Deficiency
chemical_list: D000515:alpha 1-Antitrypsin
vernacular_title: Etiologicheskoe znachenie nasledstvennogo defitsita alpha1-ingibitora proteaz v formirovanii zabolevaniĭ organov dykhaniia.