[The unusually favorable prognosis of multiple primary bronchial carcinoma--the consequence of natural killer cell elevation and increased interleukin 2 receptor expression?].
It is reported on a 65-years-old man with the metachronous type of multiple primary bronchogenic carcinoma: initial peripheral adenocarcinoma (RUL) was observed; after 7 years developed left central squamous cell carcinoma; within 5 following years no evidence for relapse. The only remaining sign of malignant disease seems to be the increase of copper-level measured in the patients serum. The elevated quantity of natural-killer-cells (CD 16) and the high-grade Interleukin-2-receptor-expression (CD 25) obtained in our patient are discussed as indicators of pathophysiological processes which could possibly lead to the favourable prognosis of this case.
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Bezirkskrankenhaus für Lungenkrankheiten und Tuberkulose Coswig.
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D000230:Adenocarcinoma / Q000276:immunology; D000368:Aged; D002283:Carcinoma, Bronchogenic / Q000276:immunology*; D002294:Carcinoma, Squamous Cell / Q000276:immunology; D003300:Copper / Q000097:blood; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*; D008175:Lung Neoplasms / Q000276:immunology*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000276:immunology*; D011379:Prognosis; D015375:Receptors, Interleukin-2 / Q000096:biosynthesis*
D015375:Receptors, Interleukin-2; D003300:Copper
Ungewöhnlich günstige Prognose eines multiplen primären Bronchialkarzinoms--Folge von Natural-Killer-Zell-Elevation und vermehrter Interleukin-2-Rezeptor-Expression?