[Pancreatic kallikrein, a protector of small intestine damage in post-ischemic toxemia].
The morphofunctional state of the small intestine was studied on a tourniquet shock model. The development of postischemic toxemia is followed by disorders of microcirculation leading to irreversible changes in the small intestine. The processes are associated with an increase of the proteolytic activity of the intestinal contents. An oral administration of andecaline prevents ischemia of the intestine, contributes to the preservation of its mucosa.
Protsenko
V A
VA
Lutsik
N G
NG
Nesterov
E N
EN
Kharchenko
V Z
VZ
D000818:Animals; D004338:Drug Combinations / Q000627:therapeutic use; D007421:Intestine, Small / Q000098:blood supply*; D007511:Ischemia / Q000150:complications* / Q000517:prevention & control; D007610:Kallikreins / Q000627:therapeutic use*; D008833:Microcirculation / Q000187:drug effects; D010179:Pancreas / Q000201:enzymology*; D010184:Pancreatic Extracts / Q000627:therapeutic use; D011205:Povidone / Q000627:therapeutic use; D051381:Rats; D011919:Rats, Inbred Strains; D014115:Toxemia / Q000188:drug therapy* / Q000209:etiology
D004338:Drug Combinations; D010184:Pancreatic Extracts; C019256:pancreatic extract, povidone drug combination; D007610:Kallikreins; D011205:Povidone
Pankreaticheskiĭ kallikrein--protektor povrezhdeniia tonkogo kishechnika pri postishemicheskoĭ toksemii.