Chromosome 6p rearrangements appear to be secondary changes in various haematological malignancies.
We report on six cases of 6p rearrangement in various haematological malignancies. On reviewing the literature, we assume 6p rearrangements to be secondary anomalies in both myeloid and lymphoid malignancies, and confirm it to be strongly associated with -5/del (5q) in myelodysplastic syndromes.
Huret
J L
JL
Département d'Hématologie et Oncologie Médicale, CNRS URA 223, Hôpital Jean Bernard, Poitiers, France.
Schoenwald
M
M
Brizard
A
A
Guilhot
F
F
Vilmer
E
E
Tanzer
J
J
D000368:Aged; D000782:Aneuploidy; D002872:Chromosome Deletion; D002895:Chromosomes, Human, Pair 5; D002896:Chromosomes, Human, Pair 6; D006402:Hematologic Diseases / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged