[Angio-protective effect of catergen in experimental liver injury].
The 120 male rats were exposed to CCl4(1 mg/kg) or ethanol (6 g/kg) to produce acute liver injury. Previous injection of cathergen (+)-cyanidonol-3) decreased the region of hepatocytes necrosis, stabilized microvessels diameter and increased muss cells degranulation. These results indicate hepatoprotective and angioprotective effect of cathergen, more expressed in exposure CCl4.
Gaskina
T K
TK
Gorchakov
V N
VN
Kurilovich
S A
SA
D000818:Animals; D001808:Blood Vessels / Q000187:drug effects*; D002251:Carbon Tetrachloride / Q000633:toxicity; D002392:Catechin / Q000494:pharmacology*; D000431:Ethanol / Q000633:toxicity; D008099:Liver / Q000187:drug effects* / Q000473:pathology; D008102:Liver Circulation / Q000187:drug effects; D008297:Male; D008833:Microcirculation / Q000187:drug effects; D051381:Rats
D000431:Ethanol; D002392:Catechin; D002251:Carbon Tetrachloride
Angioprotektivnyĭ éffekt katergena pri éksperimental'nom povrezhdenii pecheni.