title: Genetic spontaneous late subluxation of the lens. A study of two families.
abstract: Patients with genetic spontaneous late subluxation of the lens may present signs and symptoms other than lens displacement due to secondary anatomic alteration of the anterior segment. Two families are described, one of them with affected individuals in five successive generations. The vast majority of the patients sought consultation because of progressive myopia or intermittent acute intraocular hypertensive crisis which obscured the basic condition. Upon recognition of the disease, the affected patients underwent an uneventful intracapsular extraction. Histopathologic examination of the removed lenses suggested a dysplastic development of lens zonules.
authors: Centro Oftalmológico Malbran, Fundación Oftalmológica Argentina Jorge Malbran, Buenos Aires, Argentina.
authors: E S
authors: ES
authors: Malbran
authors: J O
authors: JO
authors: Croxatto
authors: C
authors: C
authors: D'Alessandro
authors: D E
authors: DE
authors: Charles
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005901:Glaucoma / Q000209:etiology; D006801:Humans; D007906:Lens Subluxation / Q000150:complications / Q000235:genetics* / Q000473:pathology; D008297:Male; D009216:Myopia / Q000209:etiology; D009798:Ocular Hypertension / Q000209:etiology; D010375:Pedigree; D014792:Visual Acuity