title: Isochromosome 12p in mediastinal germ cell tumor.
abstract: The occurrence of an i(12p) in an extragonadal mediastinal germ cell tumor indicates that this chromosome change, which is characteristic for testicular germ cell tumors, can also occur in germ cell tumors present elsewhere in the body. In addition, the karyotype in this patient was near-diploid, in contrast with testicular germ cell tumors, which as a rule are near-triploid or near-tetraploid.
authors: Centre for Human Genetics, University of Leuven, Belgium.
authors: P
authors: P
authors: Dal Cin
authors: A
authors: A
authors: Drochmans
authors: P
authors: P
authors: Moerman
authors: H
authors: H
authors: Van den Berghe
mesh_terms: D000293:Adolescent; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002881:Chromosomes, Human, Pair 12; D004407:Dysgerminoma / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007621:Karyotyping; D008297:Male; D008479:Mediastinal Neoplasms / Q000235:genetics* / Q000473:pathology