Osteocompatibility of platinum-plated titanium assessed in vitro.
Suppression of dissolution is important to increase the biocompatibility of titanium implants. Therefore, the possibility of application of platinum-coated titanium as a biomaterial was explored in in vitro experiments using the MC3T3-E1 osteogenic cell line. The data obtained from long-term cultures indicated that pure platinum or titanium thickly coated with platinum inhibited calcification significantly, suggesting that the platinum ion fails to improve the osteocompatibility of titanium implants.
Itakura
Y
Y
Department of Prosthodontics, Ohu University School of Dentistry, Fukushima, Japan.
Tajima
T
T
Ohoke
S
S
Matsuzawa
J
J
Sudo
H
H
Yamamoto
S
S
D000469:Alkaline Phosphatase / Q000378:metabolism; D001672:Biocompatible Materials; D002478:Cells, Cultured; D004247:DNA / Q000032:analysis; D004595:Electroplating; D010006:Osteoblasts / Q000378:metabolism*; D011506:Proteins / Q000032:analysis; D014025:Titanium
D001672:Biocompatible Materials; D011506:Proteins; D004247:DNA; D014025:Titanium; D000469:Alkaline Phosphatase