title: [Long-term therapy with amoxicillin and clavulanic acid in recurrent urinary tract infections in childhood].
abstract: Experiments have been carried out with an association of amoxicillin and clavulanic acid for the long-term treatment of recurrent urinary tract infections. 20 children whose antibiogram showed that the microbe in question was insensitive to amoxicillin alone were selected for treatment; five suffered from urinary tract malformations. Urine sterilisation was obtained by administering a dose of 40 mg/kg/die for five days. Treatment continued with a single evening dose of 20 mg/kg for six months. A positive result was obtained in 18 subjects (90%). One case of E. coli proved resistant to the antibiotic. In another case, treatment had to be suspended for vomiting. At the end of treatment, haematological controls proved normal.
authors: U
authors: U
authors: Ruberto
authors: P
authors: P
authors: D'Eufemia
authors: F
authors: F
authors: Martino
authors: O
authors: O
authors: Giardini
mesh_terms: D000658:Amoxicillin / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D019818:Clavulanic Acid; D002969:Clavulanic Acids / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012008:Recurrence; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D002969:Clavulanic Acids; D019818:Clavulanic Acid; D000658:Amoxicillin
vernacular_title: Terapia a lungo termine con amoxicillina ed acido clavulanico nelle infezioni recidivanti delle vie urinarie in età pediatrica.