title: [The value of ambulatory 24-hour esophageal manometry in the diagnosis of retrosternal pain of non-cardiac origin].
abstract: The clinical relevance of a system of ambulatory 24-hour oesophageal pressure and pH recording with automated data analysis was investigated in 33 unselected patients with non-cardiac chest pain. After conventional manometry with edrophonium (Tensilon) provocation, 24-hour oesophageal pH and pressure monitoring was performed. In 17 patients conventional manometry, edrophonium provocation and 24-hour pH recording revealed an oesophageal origin of the symptoms: 6 patients had oesophageal motility disorders, 3 were positive responders to edrophonium and 8 had chest pain associated with gastro-oesophageal reflux. In none of the patients who had a pain attack during prolonged oesophageal pressure recording, was a new motility disorder detected.
authors: R
authors: R
authors: Breumelhof
authors: A J
authors: AJ
authors: Smout
authors: M
authors: M
authors: Breedijk
authors: L M
authors: LM
authors: Akkermans
authors: J H
authors: JH
authors: Nadorp
mesh_terms: D002637:Chest Pain / Q000175:diagnosis* / Q000503:physiopathology; D004491:Edrophonium; D004935:Esophageal Diseases / Q000175:diagnosis / Q000503:physiopathology*; D004947:Esophagus / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008365:Manometry / Q000379:methods*; D008875:Middle Aged; D011312:Pressure
chemical_list: D004491:Edrophonium
vernacular_title: De waarde van ambulante 24-uursslokdarmmanometrie bij de diagnostiek van retrosternale pijn van niet-cardiale origine.