Breed, age, and gender differences in plasma antithrombin-III activity in clinically normal young horses.
Plasma antithrombin-III activity was quantitated in plasma samples obtained from 165 clinically normal horses 3 years old or younger. In the horses as a group, antithrombin-III activity ranged from 63 to 131% of a species-specific reference plasma. Thoroughbred horses had significantly higher antithrombin-III activity (103.3 +/- 18.3; mean +/- SD) than did Standardbred horses (92.3 +/- 14.2). The plasma antithrombin-III activities were significantly lower in horses younger than 16 months old when compared with those in more mature horses (3 years old). There was no statistically significant gender-related effect on plasma antithrombin-III activity. Breed and age factors should therefore be taken into consideration when interpreting plasma antithrombin-III activity in horses.
Johnstone
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Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Canada.
Physick-Sheard
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Crane
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D000367:Age Factors; D000704:Analysis of Variance; D000818:Animals; D000990:Antithrombin III / Q000032:analysis*; D001947:Breeding; D005260:Female; D006736:Horses / Q000097:blood*; D008297:Male; D012016:Reference Values; D012737:Sex Factors; D013045:Species Specificity
D000990:Antithrombin III