[Method for evaluating the reinforcing properties of morphine in a model of addictive behavior].
An animal model of addiction is described. The albino rats learned to come into the right arm of the Y-type maze where they received intraperitoneal injections of morphine in a dose of 5 mg/kg or distilled water (control group). It was found that morphine-dependent rats much more frequently visited the right arm. Thus it is possible to estimate quantitatively the positive reinforcing effect of morphine.
Surkova
L A
LA
Tiurina
I V
IV
D000818:Animals; D004195:Disease Models, Animal; D007858:Learning / Q000187:drug effects; D008297:Male; D009020:Morphine / Q000494:pharmacology*; D009021:Morphine Dependence; D051381:Rats; D012044:Regression Analysis; D012054:Reinforcement, Psychology
D009020:Morphine
Sposob otsenki podkrepliaiushchikh svoĭstv morfina na modeli patologicheskogo vlecheniia.