[Interaction of quinidine, lidocaine, tricaine and pyromecaine with heparin].
In the experiments on rabbits it was shown that quinidine administered intravenously in a dose of 5 mg/kg exerts no effect on the blood coagulability but decreases the degree and duration of the anticoagulant effect of heparin. Lidocaine, trimecaine and pyromecaine at the same dose alter neither the blood coagulability nor the anticoagulant effect of heparin.
Ushkalova
E A
EA
Petrov
A D
AD
Shcheglova
N V
NV
D062365:Aminobenzoates / Q000494:pharmacology*; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology*; D001777:Blood Coagulation / Q000187:drug effects; D015237:Dinoprost / Q000031:analogs & derivatives* / Q000494:pharmacology; D004347:Drug Interactions; D006493:Heparin / Q000494:pharmacology*; D008012:Lidocaine / Q000494:pharmacology*; D011759:Pyrrolidines / Q000494:pharmacology*; D011802:Quinidine / Q000494:pharmacology*; D011817:Rabbits; D013918:Thrombin Time
D062365:Aminobenzoates; D000889:Anti-Arrhythmia Agents; D011759:Pyrrolidines; C003636:tricaine; C000661:bumecain; C061624:11-fluoro-11-deoxyprostaglandin F2alpha; D006493:Heparin; D008012:Lidocaine; D015237:Dinoprost; D011802:Quinidine
Issledovanie vzaimodeĭstviia khinidina, lidokaina, trikaina i piromekaina s geparinom.