Studies on antifungal properties of phenol complexes with secondary amines. 3. The antimycotic activity of the complex of 2,4,5-trichlorophenol with dicyclohexylamine in the treatment of experimental mycosis.
2,4,5-trichlorophenol complexed with dicyclohexylamine was used for treatment of experimental mycosis. From the mycological and clinical evaluation the conclusion can be drawn that the effect of phenol in lipophilic ointment is comparable to that of clotrimazole (Canesten-cream "Polfa" licensed by Bayer) with the statistical significance p less than 0.001.
Kubis
A
A
Witek
R
R
Szcześniak
M
M
D015085:2,4,5-Trichlorophenoxyacetic Acid / Q000627:therapeutic use*; D000818:Animals; D000935:Antifungal Agents / Q000627:therapeutic use*; D003514:Cyclohexylamines / Q000627:therapeutic use*; D005260:Female; D006168:Guinea Pigs; D008297:Male; D009181:Mycoses / Q000188:drug therapy*
D000935:Antifungal Agents; D003514:Cyclohexylamines; C011769:dicyclohexylamine; D015085:2,4,5-Trichlorophenoxyacetic Acid