[Mass screening of neonates for histidinemia].
The authors report on newborn mass-screening for histidinemia by Guthrie bacterium inhibition assay. 51,618 newborns were screened and 805 cases with more than 5 mg% histidine blood level were found. A second test, urocanic acid thin-layer chromatography was done from these samples. According to these tests no histidinemic patient was detected. It is worth mentioning that blood histidine level exceeded 20 mg% in 55 cases from 805 newborns. Considering our screening results, the low incidence and the relatively good prognosis of the disease, a mass-screening in Hungary is not necessary.
Havass
Z
Z
Tóth
E
E
D006639:Histidine / Q000097:blood*; D006801:Humans; D006814:Hungary; D007231:Infant, Newborn / Q000097:blood*; D008403:Mass Screening
D006639:Histidine
A histidinaemia újszülöttkori tömegszürövizsgálata.