Differentiation of the golden hamster oviduct epithelial cells during postnatal development: an electron microscopic study.
The ultrastructural changes in the process of differentiation of the epithelial cells of the golden hamster oviduct during postnatal development were investigated by means of electron microscopy. In the epithelium of the ampulla of the neonatal oviducts, no differentiated ciliated cells or secretory cells were identified. In these undifferentiated cells, free ribosomes were well developed, but rough endoplasmic reticulum (RER) and the Golgi apparatus were undeveloped. Cells undergoing ciliogenesis were first identified at 3.5 days after birth, and some ciliated cells appeared at 4.5 days. In the nonciliated cells, marked changes in the organelles were observed at this time. Subsequently, some nonciliated cells containing well-developed RER and Golgi apparatus were observed at 9.5 to 10.5 days after birth, and a few mature secretory cells were observed at 10.5 days. An increase in secretory granules occurred in the secretory cells at 12.5-15.5 days after birth. Many fully mature ciliated and secretory cells were observed at 15.5 days after birth. After 20.5 days after birth, the epithelium was identical with that of the adult golden hamster. Quantitative data indicated that the differentiation of ciliated cells began earlier and took place over a more extended period of time than did that of the secretory cells in the golden hamster oviduct during postnatal development.
Abe
H
H
Developmental and Reproductive Biology Center, Yamagata, Japan.
Oikawa
T
T
D000818:Animals; D000831:Animals, Newborn; D002454:Cell Differentiation; D002923:Cilia / Q000648:ultrastructure; D006224:Cricetinae / Q000254:growth & development*; D004721:Endoplasmic Reticulum / Q000502:physiology / Q000648:ultrastructure; D004847:Epithelial Cells; D004848:Epithelium / Q000648:ultrastructure; D005187:Fallopian Tubes / Q000166:cytology* / Q000648:ultrastructure; D005260:Female; D006056:Golgi Apparatus / Q000502:physiology / Q000648:ultrastructure; D008647:Mesocricetus / Q000254:growth & development*; D008854:Microscopy, Electron; D008928:Mitochondria / Q000502:physiology / Q000648:ultrastructure