title: Cervical intraepithelial neoplasia with conization: early complications and follow-up.
abstract: The authors made a review of the last 100 cases who underwent a conization of the cervix during the period 1980-1986. Cyto-histological evaluation was compatible in 78% of the cases with a cervical intraepithelial neoplasia of third degree and in 22% with a CIN of first and second degree. Early post-operative complications consisted of a hemorrhage in 3% of the cases, easily stopped with a vaginal packing. In 2% of the cases a risuture under general anaesthesia was required. In 1 case the stitches loosened and in another a urinary infection was present. Twenty-six patients underwent total hysterectomy after conization for different indications; only one patient had a relapse after six months as there was a moderate dysplasia localized in the vaginal vault. During the follow-up, 14 patient became pregnant. Among these, 5 underwent legal termination during the first trimester and 9 delivered at term without any complication. During these follow-up of 7 years in the older cases and 6 months in the more recent ones, 6 cases displayed a persistence of the disease after 3 months, (CIN of variable degree) and 2 cases relapsed at the second colpocytological control. These patients, according to the age and the presence of clinical indications, underwent total hysterectomy or diathermic coagulation with resolution of the disease. A relapsing invasive tumor was never observed.)
authors: Obstetrics and Gynaecology Department, Children's Institute, Trieste, Italy.
authors: S
authors: S
authors: Alberico
authors: M C
authors: MC
authors: Facca
authors: L
authors: L
authors: Dal Corso
authors: L
authors: L
authors: Di Bonito
authors: I
authors: I
authors: Colautti
authors: R
authors: R
authors: Casaccia
authors: P
authors: P
authors: Bogatti
authors: G P
authors: GP
authors: Mandruzzato
mesh_terms: D000328:Adult; D002584:Cervix Uteri / Q000473:pathology / Q000601:surgery; D004848:Epithelium / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D002583:Uterine Cervical Neoplasms / Q000150:complications* / Q000473:pathology