Cerebellar tumor causing hypertensive crisis and simulating pheochromocytoma and Cushing's syndrome.
We describe a case of posterior fossa medulloblastoma in which the initial symptom was severe hypertension that evolved into a hypertensive crisis. Initial diagnostic evaluation was suggestive of both pheochromocytoma and Cushing's syndrome: elevated plasma norepinephrine and urine VMA, normal ACTH level with elevated plasma and urine cortisol, and lack of suppressibility with dexamethasone. CAT scan and cerebral angiogram subsequently revealed the presence of an intracranial mass. After surgical removal of the tumor, blood pressure pattern and endocrine abnormalities reverted to normal.
Yagil
Y
Y
Futterweit
W
W
Krakoff
L R
LR
Rubin
H
H
Weinrauch
H
H
D000310:Adrenal Gland Neoplasms / Q000175:diagnosis*; D000328:Adult; D002528:Cerebellar Neoplasms / Q000150:complications* / Q000175:diagnosis; D003480:Cushing Syndrome / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D008297:Male; D008527:Medulloblastoma / Q000150:complications* / Q000175:diagnosis; D010673:Pheochromocytoma / Q000175:diagnosis*