Four open mammillary and catenary compartment models for pharmacokinetics studies.
A mathematical method is proposed to solve a fourth degree equation which gives the eigenvalues of the matrix connected with a four open compartment model used in pharmacokinetic studies. As examples, the method is applied to mammillary and catenary models.
de Biasi
J
J
Biomathématiques, UFR de Mathématiques, Université Paul Sabatier, Toulouse, France.
D003198:Computer Simulation; D008432:Mathematical Computing; D008954:Models, Biological; D010599:Pharmacokinetics; D012985:Software Design