title: [The functional role of the oxytocin-sensitive hippocampal system in organizing the mechanisms of morphine addiction].
abstract: The effect of oxytocin (OXT) administration into the brain ventricles on the process of narcotic dependence formation was studied before and following hippocampal lesion. OXT was found to inhibit the process of narcotic dependence formation. The hippocampal lesion weakened the inhibitory effect. A specific hippocampal involvement in the processes of narcotic reinforcement was suggested.
authors: R Sh
authors: RSh
authors: Ibragimov
mesh_terms: D000818:Animals; D004564:Electrocoagulation; D006624:Hippocampus / Q000187:drug effects* / Q000502:physiology; D007276:Injections, Intraventricular; D008845:Microinjections; D009020:Morphine / Q000008:administration & dosage; D009021:Morphine Dependence / Q000209:etiology* / Q000503:physiopathology; D010121:Oxytocin / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D012646:Self Administration; D012653:Self Stimulation / Q000187:drug effects / Q000502:physiology
chemical_list: D010121:Oxytocin; D009020:Morphine
vernacular_title: Funktsional'naia rol' oksitotsinchuvstvitel'noĭ sistemy gippokampa v organizatsii mekhanizmov vlecheniia k morfinu.