title: Effect of sternotomy and cardiopulmonary bypass on airway pressures and respiratory mechanics during high frequency ventilation.
abstract: The airway pressures at ventilatory frequencies of 15, 60, 100, 120 and 150 breaths per minute were measured in eight adult patients undergoing coronary artery bypass grafting. Measurements were made perioperatively at four stages: precardiopulmonary bypass with the chest closed, precardiopulmonary bypass with the chest open, postcardiopulmonary bypass with the chest open and postcardiopulmonary bypass with the chest closed. In five patients thoracic compliance and airways resistance were also measured at these times. Neither sternotomy nor cardiopulmonary bypass made any significant difference to the airway pressures during normal and high frequency ventilation, nor were lung mechanics affected.
authors: Department of Anaesthetics, Royal Postgraduate Medical School, Hammersmith Hospital, London, U.K.
authors: C E
authors: CE
authors: Harris
authors: M
authors: M
authors: Cody
authors: M K
authors: MK
authors: Chakrabarti
authors: J G
authors: JG
authors: Whitwam
mesh_terms: D000403:Airway Resistance; D001784:Blood Gas Analysis; D002315:Cardiopulmonary Bypass; D006612:High-Frequency Ventilation; D006801:Humans; D008168:Lung / Q000502:physiology*; D008170:Lung Compliance; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D011312:Pressure; D012123:Pulmonary Ventilation; D015656:Respiratory Mechanics; D013249:Sternum / Q000601:surgery*; D013990:Tidal Volume
chemical_list: D010100:Oxygen