Obstetric acute renal failure 1956-1987.
A total of 142 women with severe acute renal failure (ARF) resulting from obstetric causes was treated by dialysis at a single centre from 1956 to 1987. One-year survival was 78.6%, which compares favourably with other causes of ARF. Abortion, haemorrhage and preclampsia comprised 95% of cases, with survival being best (82.9%) with abortion. Survival was adversely affected by increasing age. Acute cortical necrosis (12.7% of patients) carried 100% mortality after 6 years. Follow-up of survivors showed normal renal function up to 31 years following ARF; 25-year patient survival was 71.6%. Improvements in obstetric care and the disappearance of illegal abortions have resulted in a dramatic decline in the incidence of obstetric ARF.
Turney
J H
JH
Renal Unit, General Infirmary, Leeds.
Ellis
C M
CM
Parsons
F M
FM
D000206:Actuarial Analysis; D058186:Acute Kidney Injury / Q000209:etiology / Q000401:mortality* / Q000628:therapy; D000328:Adult; D004739:England / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008423:Maternal Age; D011247:Pregnancy; D011248:Pregnancy Complications / Q000401:mortality* / Q000628:therapy; D006435:Renal Dialysis; D012189:Retrospective Studies; D013997:Time Factors