title: Orthopedic aspects of Rett syndrome: a multicenter review.
abstract: Twenty-three of 36 patients (64%) with Rett syndrome showed orthopedic problems at an average age of 8 years 7 months. Sixteen patients had spinal deformities (45%), six had scoliosis, one had sagittal deformity, and nine had scoliosis with sagittal deformity. Eight patients with scoliosis have shown progression, with two patients requiring surgery. Thirteen patients (36%) exhibited joint contractures; three of them have required surgery. Ten fractures occurred in five patients (14%). Coxa valga was present in all 14 hips. Skeletal ages in four preadolescent patients were normal.
authors: Department of Orthopaedic Surgery, Children's Hospital, Detroit, Michigan.
authors: R T
authors: RT
authors: Loder
authors: C L
authors: CL
authors: Lee
authors: B S
authors: BS
authors: Richards
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003286:Contracture / Q000151:congenital* / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007738:Kyphosis / Q000151:congenital* / Q000628:therapy; D012600:Scoliosis / Q000151:congenital* / Q000628:therapy; D013577:Syndrome