Effects of extracellular products from Staphylococcus saprophyticus on human lymphocytes.
Extracellular products from Staphylococcus saprophyticus were isolated and tested for their effect on the lymphoproliferative activity of con A and LPS and on the growth of human lymphocytes. The stimulatory effects of con A or LPS were not affected but a T-cell mitogenic activity was noted after 5 days of incubation. The extracellular material was separated by gel chromatography and the mitogenic activity was shown to be located to the protein fraction.
Hjelm
E
E
Department of Clinical Bacteriology, University of Uppsala, Sweden.
Lundell-Etherden
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I
D003208:Concanavalin A / Q000494:pharmacology; D012739:Gonadal Steroid Hormones / Q000494:pharmacology; D006801:Humans; D008070:Lipopolysaccharides / Q000494:pharmacology; D008213:Lymphocyte Activation / Q000187:drug effects*; D008934:Mitogens / Q000302:isolation & purification*; D013210:Staphylococcus / Q000032:analysis*
D012739:Gonadal Steroid Hormones; D008070:Lipopolysaccharides; D008934:Mitogens; D003208:Concanavalin A