title: [Effects of synthetic new drug SC1001-sodium on respiratory frequency, heart rate, rectal temperature and electrocorticogram in rabbits].
abstract: Seventeen normal male rabbits weighing 1.7-2.8 kg were randomly divided into 2 groups. The experimental group (ten rabbits) was injected with SC1001Na (200 mg/kg, i.p.). The control group (seven rabbits) was injected with normal saline of the same volume. Continuous observations for 6 hours were made after injection, with reference to respiratory frequency (RF), heart rate (HR), rectal temperature (RT) and ECoG of these rabbits. The results of experiments indicate that SC1001Na has a slight inhibitory effect on RF and RT, an obvious inhibitory effect on the activity of central nervous system, and an accelerating effect on HR in rabbits.
authors: Q X
authors: QX
authors: Chen
authors: H X
authors: HX
authors: Chai
authors: Y G
authors: YG
authors: Xie
authors: J G
authors: JG
authors: Xu
mesh_terms: D000818:Animals; D001831:Body Temperature / Q000187:drug effects*; D002934:Cinnamates / Q000494:pharmacology*; D004569:Electroencephalography; D006339:Heart Rate / Q000187:drug effects*; D008297:Male; D011817:Rabbits; D012007:Rectum; D012119:Respiration / Q000187:drug effects*
chemical_list: D002934:Cinnamates; C058003:SC 1001A