title: Hemodynamic and oxygen transport response to modified fluid gelatin in critically ill patients.
abstract: The hemodynamic and oxygen transport effects of the rapid infusion of 500 ml of modified fluid gelatin, an artificial colloid widely used in Europe, were studied in a group of critically ill patients suffering from cardiovascular instability. Oxygen consumption tended to increase. There were no significant changes in heart rate, shunt fraction, or systemic vascular resistance index. There were significant increases in mean arterial pressure, pulmonary artery wedge pressure, stroke index, cardiac index, and oxygen delivery. There were significant decreases in Hgb concentration and arterial oxygen content. The overall circulatory effects of modified fluid gelatin are beneficial.
authors: Intensive Care Unit, University Hospital of South Manchester, Withington, UK.
authors: J D
authors: JD
authors: Edwards
authors: P
authors: P
authors: Nightingale
authors: R G
authors: RG
authors: Wilkins
authors: E B
authors: EB
authors: Faragher
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure; D003102:Colloids; D003422:Critical Care; D005260:Female; D005780:Gelatin / Q000008:administration & dosage*; D006323:Heart Arrest / Q000503:physiopathology; D006439:Hemodynamics; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption; D010952:Plasma Substitutes; D011446:Prospective Studies; D012769:Shock / Q000503:physiopathology; D013318:Stroke Volume; D013386:Succinates / Q000008:administration & dosage*
chemical_list: D003102:Colloids; D010952:Plasma Substitutes; D013386:Succinates; C060085:succinylated gelatin; D005780:Gelatin