title: [The effect of histamine on the rosette-forming ability of T-lymphocytes upon immunization with DPT vaccine and its components].
abstract: The influence exerted by histamine on the capacity of T-lymphocytes for spontaneous rosette formation in intact animals and in animals immunized with adsorbed DPT vaccine and its components has been studied. Histamine at a concentration of 10(-3) M has been found to produce an inhibitory effect on the capacity of lymphocytes in the blood and spleen of guinea pigs immunized with adsorbed DPT vaccine and its components for spontaneous rosette formation. This effect of histamine has proved to be even more pronounced after the immunization of the animals with adsorbed DPT vaccine and Bordetella pertussis suspension, which is probably due to their sensitizing action.
authors: M N
authors: MN
authors: Kamalova
authors: N R
authors: NR
authors: Nuriddinova
mesh_terms: D000818:Animals; D004168:Diphtheria Toxoid; D015721:Diphtheria-Tetanus-Pertussis Vaccine; D004338:Drug Combinations; D006168:Guinea Pigs; D006632:Histamine / Q000276:immunology*; D010567:Pertussis Vaccine; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*; D013745:Tetanus Toxoid
chemical_list: D004168:Diphtheria Toxoid; D015721:Diphtheria-Tetanus-Pertussis Vaccine; D004338:Drug Combinations; D010567:Pertussis Vaccine; D013745:Tetanus Toxoid; D006632:Histamine
vernacular_title: Vliianie gistamina na rozetkoobrazuiushchuiu sposobnost' T-limfotsitov pri immunizatsii AKDS-vaktsinoĭ i ee komponentami.