title: [Low activity of antioxidant enzymes in tumor cells as a factor of oxygen dependence of antitumor cytotoxicity of macrophages].
abstract: The author studied dependence of cytotoxicity of peritoneal macrophages of Wistar rats on the production of active oxygen form (AOF) and activity of antioxidative enzymes in target cells. Low activity of glutathione-peroxidase and glutathione-reductase in K562 cells could be the cause of macrophage cytotoxicity realization along AOF-dependent way.
authors: E V
authors: EV
authors: Borunov
authors: I V
authors: IV
authors: Khavalkin
authors: L P
authors: LP
authors: Smirnova
authors: I A
authors: IA
authors: Shchepetkin
authors: V Z
authors: VZ
authors: Lankin
authors: N V
authors: NV
authors: Vasil'ev
mesh_terms: D000818:Animals; D002460:Cell Line; D003602:Cytotoxicity, Immunologic; D005979:Glutathione Peroxidase / Q000378:metabolism*; D005980:Glutathione Reductase / Q000378:metabolism*; D008264:Macrophages / Q000276:immunology*; D051379:Mice; D009374:Neoplasms, Experimental / Q000201:enzymology / Q000276:immunology / Q000378:metabolism*; D010100:Oxygen; D051381:Rats; D013053:Spectrophotometry; D014407:Tumor Cells, Cultured
chemical_list: D005979:Glutathione Peroxidase; D005980:Glutathione Reductase; D010100:Oxygen
vernacular_title: Nizkaia aktivnost' antioksidantnykh fermentov v opukholevykh kletkakh kak faktor kislorodnoĭ zavisimosti protivoopukholevoĭ tsitotoksichnosti makrofagov.