title: The primary structure of a feline class I gene: striking similarity to HLA-A.
abstract: The sequence of a feline class I pseudogene and its comparison with class I genes from other species is presented. The gene isolated is a pseudogene because of the presence of four stop codons and two frame shift mutations in the first- and second-domain encoding exons, as well as a mutation in a splice acceptor site in the third intron. By sequence comparison with the other class I sequences determined to date, the FLA pseudogene is most closely related to the HLA-A locus products (88% nucleotide identity.
authors: Department of Cellular Biochemistry, The Netherlands Cancer Institute, Amsterdam.
authors: M
authors: M
authors: van Hoof
authors: J P
authors: JP
authors: de Geus
authors: M
authors: M
authors: Roos
authors: C
authors: C
authors: Brown
authors: H
authors: H
authors: Jacobs
authors: H
authors: H
authors: Ploegh
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D002415:Cats / Q000235:genetics* / Q000276:immunology; D005796:Genes; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D008285:Major Histocompatibility Complex; D008969:Molecular Sequence Data; D015183:Restriction Mapping
chemical_list: D015395:Histocompatibility Antigens Class I