[Ultramicroscopic organization of the vascular plexus in the rabbit cerebral lateral ventricles and its changes under the effect of pyrogens].
By means of electron microscopical methods organization of various components of the vascular plexus in the rabbit cerebral lateral ventricles--ependymal and supraependymal cells, as well as capillaries, making the base of the hemato-encephalic and hemato-liquor barriers of the plexus have been studied. Injection of bacterial pyrogen (pyrogenal) to the animals is accompanied with an increasing permeability in the barriers of the vascular plexus for certain blood cells (lymphocytes, monocytes), their activation and transformation into plasma cells and macrophages. Under pyrogenal effect in the ventricle cavities activation of the supraependymal cells and intensification of their interaction with the underlying ependyma take place. In the ependymal layer local dilatation of intercellular spaces and intensification of exocytic processes are observed. The changes revealed demonstrate an active reaction of some elements of the vascular plexus to fever, dependent on injection of the bacterial pyrogens into the organism.
Archakova
L I
LI
Beliavskiĭ
E M
EM
Gurin
V N
VN
D000818:Animals; D002552:Cerebral Ventricles / Q000098:blood supply* / Q000648:ultrastructure; D008214:Lymphocytes / Q000648:ultrastructure; D008264:Macrophages / Q000648:ultrastructure; D008833:Microcirculation / Q000648:ultrastructure; D008854:Microscopy, Electron; D009000:Monocytes / Q000648:ultrastructure; D010950:Plasma Cells / Q000648:ultrastructure; D011749:Pyrogens / Q000633:toxicity*; D011817:Rabbits
D011749:Pyrogens
Ul'tramikroskopicheskaia organizatsiia sosudistogo spleteniia bokovykh zheludochkov mozga krolika i ee izmeneniia pri deĭstvii pirogenov.