Long-term follow-up of potentiation of radiotherapy by cis-platinum in advanced cervical cancer.
Between January 1982 and January 1983 all patients with advanced cervical cancer were randomized into three groups: radiotherapy only (group I), radiotherapy plus weekly cis-platinum (group II), and radiation plus twice-weekly cis-platinum (group III). Better initial central control was observed in group III patients. Long-term survival was similar in the three groups. Potentiation of radiotherapy with cis-platinum failed to show any significant improvement in long-term survival.
Wong
L C
LC
Department of Obstetrics and Gynaecology, University of Hong Kong.
Choo
Y C
YC
Choy
D
D
Sham
J S
JS
Ma
H K
HK
D002945:Cisplatin / Q000627:therapeutic use*; D003131:Combined Modality Therapy / Q000009:adverse effects; D005260:Female; D005500:Follow-Up Studies; D005767:Gastrointestinal Diseases / Q000139:chemically induced; D006402:Hematologic Diseases / Q000139:chemically induced; D006801:Humans; D009364:Neoplasm Recurrence, Local; D011838:Radiation-Sensitizing Agents; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*
D011838:Radiation-Sensitizing Agents; D002945:Cisplatin