Eyelid movement abnormalities in progressive supranuclear palsy.
We systematically videotaped eyelid movements in a community-based series of 38 patients with progressive supranuclear palsy (PSP). Ten patients (26%) had blepharospasm, "apraxia" of lid opening and/or "apraxia" of lid closing. These patients as a group had more severe upgaze paresis but no greater disease duration than the patients without supranuclear lid dysfunction. Patients used a variety of synkinetic movements to overcome lid-movement abnormalities. One patient displayed "slow blinks," a phenomenon not previously described in PSP. Blink rate in PSP, 3.0/min, was markedly lower than that in patients with Parkinson's disease (PD), 12.5/min, and patients with PSP but not PD increased their blink rate during command versional eye movements.
Golbe
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LI
Department of Neurology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick 08903.
Davis
P H
PH
Lepore
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FE
D000368:Aged; D000369:Aged, 80 and over; D001072:Apraxias / Q000503:physiopathology; D001764:Blepharospasm / Q000503:physiopathology; D001767:Blinking; D005143:Eyelids / Q000503:physiopathology*; D006801:Humans; D008875:Middle Aged; D013494:Supranuclear Palsy, Progressive / Q000150:complications / Q000503:physiopathology*; D014743:Videotape Recording