title: Cutaneous and extracutaneous neutrophilic infiltrates (Sweet syndrome) in three patients with Fanconi anemia.
abstract: Three patients with coexistent Fanconi syndrome and Sweet syndrome (neutrophilic dermatosis) are presented. These sterile skin lesions responded to systemic corticosteroid therapy in all three cases, and recurred when treatment was discontinued. The association in children of Sweet syndrome with malignancy has previously been recognized; it has not been reported in the premalignant phase of Fanconi anemia. This report expands the differential diagnosis of the neutrophilic dermatoses. Children with Sweet syndrome and anemia should be examined for Fanconi anemia by diepoxybutane cytogenetic studies.
authors: Department of Medicine, University of Washington School of Medicine, Seattle.
authors: F
authors: F
authors: Baron
authors: V P
authors: VP
authors: Sybert
authors: R G
authors: RG
authors: Andrews
mesh_terms: D000328:Adult; D002648:Child; D005198:Fanconi Syndrome / Q000150:complications*; D005260:Female; D005334:Fever; D006801:Humans; D008297:Male; D009504:Neutrophils; D012871:Skin Diseases / Q000473:pathology*; D013577:Syndrome