Magnetic resonance findings in REM sleep behavior disorder.
Rapid eye movement (REM) sleep behavior disorder is characterized by bizarre acts during nocturnal sleep that may lead to physical injuries. Dream content suggests that motor overactivity is an attempted dream enactment and polygraphic studies reveal REM stage without atonia, an alteration of REM sleep generation that facilitates excessive motor activity. In 6 patients with REM sleep behavior disorder. MRI of the brain showed multifocal signal intensity lesions suggestive of lacunar infarcts in periventricular regions (5 patients) and in dorsal pontomesencephalic areas (3 patients). REM sleep behavior disorder may be the result of injury to the midrostral tegmentum nuclei, the tegmentoreticular tracts, or both. This condition is easily controlled with clonazepam.
Culebras
A
A
Neurology Service, Veterans Administration Medical Center, Syracuse, NY 13210.
Moore
J T
JT
D000368:Aged; D002998:Clonazepam / Q000627:therapeutic use; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000503:physiopathology; D012893:Sleep Wake Disorders / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D012895:Sleep, REM; D014947:Wounds and Injuries / Q000209:etiology
D002998:Clonazepam