Nonrefluxing colonic conduits: a long-term life-table analysis.
We evaluated 25 patients undergoing urinary diversion with a nonrefluxing colonic conduit. Renal scarring developed in 10% of the kidneys during a median followup of 12.7 years. In 11 renal units (22%) deterioration of the ureteroenteric anastomosis occurred due to the development of reflux or stricture. Of these kidneys 45% had scarring; no renal unit in which the anastomosis remained intact had renal scars (p less than 0.001). Of our patients 96% had bacterial colonization of the colonic conduit but this was not associated with renal scarring if the urinary diversion was anatomically intact.
Husmann
D A
DA
University of Texas Southwestern Medical Center, Dallas.
McLorie
G A
GA
Churchill
B M
BM
D001437:Bacteriuria; D001746:Bladder Exstrophy / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D002921:Cicatrix / Q000209:etiology / Q000473:pathology; D003106:Colon; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007668:Kidney / Q000473:pathology; D015993:Life Tables; D011183:Postoperative Complications; D011704:Pyelonephritis / Q000209:etiology; D012189:Retrospective Studies; D014547:Urinary Diversion / Q000379:methods*