title: The INT1 oncogene is not rearranged or amplified in lipomas with structural chromosomal abnormalities of 12q13-15.
abstract: DNA from nine different solitary subcutaneous lipomas, all with clonal abnormalities affecting the chromosome segment 12q13-15, was examined for rearrangement or amplification of a human INT1 gene sequence. INT1 is a putative oncogene that has been localized to the chromosome band 12q13. No rearrangement or amplification could be detected.
authors: Department of Clinical Genetics, University Hospital, Lund, Sweden.
authors: K
authors: K
authors: Arheden
authors: N
authors: N
authors: Mandahl
authors: S
authors: S
authors: Heim
authors: F
authors: F
authors: Mitelman
mesh_terms: D002881:Chromosomes, Human, Pair 12; D004247:DNA / Q000235:genetics; D005784:Gene Amplification; D015321:Gene Rearrangement; D006801:Humans; D008067:Lipoma / Q000235:genetics*; D009693:Nucleic Acid Hybridization; D009857:Oncogenes; D015183:Restriction Mapping
chemical_list: D004247:DNA