title: [The hyper IgE syndrome (Buckley syndrome)].
abstract: An exceptional case is reported of hyper IgE syndrome and membranoproliferative glomerulonephritis with onset in 1964. Renal disease, symptoms of hyper IgE syndrome and level of serum IgE were improved by a long-term cyclosporine treatment (3/5 mg/kg/day) with a follow-up of 4 years. The characteristics of the hyper IgE syndrome, described by Buckley in 1972 are given and the respective roles of IgE-BF, IL4 and interferon in the mechanism of increase in serum IgE is discussed.
authors: Service de Néphrologie, Hôpital Henri-Mondor, Créteil.
authors: J
authors: J
authors: Laurent
authors: G
authors: G
authors: Rostoker
authors: G
authors: G
authors: Lagrue
mesh_terms: D003524:Cyclosporins / Q000627:therapeutic use; D015433:Glomerulonephritis, Membranous / Q000276:immunology*; D006801:Humans; D006942:Hypergammaglobulinemia / Q000276:immunology*; D007073:Immunoglobulin E / Q000276:immunology*; D015847:Interleukin-4 / Q000502:physiology; D008222:Lymphokines / Q000502:physiology; D029584:Prostatic Secretory Proteins
chemical_list: D003524:Cyclosporins; D008222:Lymphokines; D029584:Prostatic Secretory Proteins; C043076:beta-microseminoprotein; C013059:immunoglobulin-binding factors; D015847:Interleukin-4; D007073:Immunoglobulin E
vernacular_title: Le syndrome hyper IgE (syndrome de Buckley).