[Patterns of the forming of an immunologic memory to staphylococcal corpuscular antigen].
The experiments carried out on inbred mice have revealed that the level of the immunological memory to staphylococci depends on the intensity of the antigenic stimulation; high priming dose of antigen proving to be the most effective one. The opposite character of immune responsiveness observed during primary antibody response to particulate staphylococcal antigen in C3H and A/Sn mice increased after the second immunization. It is established that immunological memory to staphylococci may be induced in genetically athymic mice. Many antibody-forming cells are found in the bone marrow of the secondary immunized mice. This phenomenon may be due to the repopulation of the bone marrow tissue by recirculating memory cells.
Liashchenko
K P
KP
Bobrovnik
S A
SA
Golovanova
T A
TA
D000373:Agglutinins / Q000032:analysis; D000818:Animals; D000921:Antibody-Producing Cells / Q000276:immunology; D000942:Antigens, Bacterial / Q000276:immunology*; D001853:Bone Marrow / Q000276:immunology; D004306:Dose-Response Relationship, Immunologic; D005838:Genotype; D007114:Immunization; D007156:Immunologic Memory; D051379:Mice; D008815:Mice, Inbred Strains; D008819:Mice, Nude; D013154:Spleen / Q000276:immunology; D013210:Staphylococcus / Q000276:immunology*
D000373:Agglutinins; D000942:Antigens, Bacterial
Zakonomernosti formirovaniia immunologicheskoĭ pamiati k korpuskuliarnomu antigenu stafilokokka.