Oxalate: effect on calcium absorbability.
Absorption of calcium from intrinsically labeled Ca oxalate was measured in 18 normal women and compared with absorption of Ca from milk in these same subjects, both when the test substances were ingested in separate meals and when ingested together. Fractional Ca absorption from oxalate averaged 0.100 +/- 0.043 when ingested alone and 0.140 +/- 0.063 when ingested together with milk. Absorption was, as expected, substantially lower than absorption from milk (0.358 +/- 0.113). Nevertheless Ca oxalate absorbability in these women was higher than we had previously found for spinach Ca. When milk and Ca oxalate were ingested together, there was no interference of oxalate in milk Ca absorption and no evidence of tracer exchange between the two labeled Ca species.
Heaney
R P
RP
Creighton University, Omaha, NE 68178.
Weaver
C M
CM
D000328:Adult; D000818:Animals; D001682:Biological Availability; D002118:Calcium / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D002129:Calcium Oxalate / Q000008:administration & dosage / Q000493:pharmacokinetics*; D005260:Female; D006801:Humans; D007408:Intestinal Absorption / Q000187:drug effects*; D008892:Milk / Q000378:metabolism; D012588:Scintillation Counting; D013054:Spectrophotometry, Atomic
D002129:Calcium Oxalate; D002118:Calcium