[Changes in the rosette-forming capacity of peripheral blood lymphocytes in patients with ischemic heart disease after administration of atherogenic lipoproteins].
Low-density lipoproteins, isolated from the serum of patients with hypercholesterolemia (dislipoproteinemia, type IIa), increased significantly the number of active and recovered rosette-forming cells (RFC) at incubation with lymphocytes of coronary patients. The use of lipoproteins, belonging to all atherogenic classes, did not essentially alter lymphocyte ability to form total E-RFC. Purified apolipoprotein B reduced lymphocyte capacity for active rosette formation.
Vasil'chenko
E M
EM
Beĭko
V A
VA
Tymchishin
P N
PN
Karpov
R S
RS
D000276:Adjuvants, Immunologic / Q000276:immunology; D003327:Coronary Disease / Q000276:immunology*; D003470:Culture Media; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000276:immunology; D007166:Immunosuppressive Agents; D066298:In Vitro Techniques; D008077:Lipoproteins, LDL / Q000494:pharmacology*; D008079:Lipoproteins, VLDL / Q000494:pharmacology*; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*
D000276:Adjuvants, Immunologic; D003470:Culture Media; D007166:Immunosuppressive Agents; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL
Izmenenie rozetkoobrazuiushcheĭ sposobnosti limfotsitov perifericheskoĭ krovi bol'nykh ishemicheskoĭ bolezn'iu serdtsa pod deĭstviem lipoproteidov aterogennykh klassov.