Cross-sectional and longitudinal relationships between physical fitness and risk factors for coronary heart disease in men and women: "the Adelaide 1000".
Measurements of aerobic fitness, weight, blood pressure, and lipids were made in 1000 sedentary men and women entering a fitness programme, and were repeated 2 years later in 733 subjects. Cross-sectional analyses including (a) comparisons of CHD risk factors in subjects grouped as "low", "low/moderate", "moderate/high", and "high" fitness, and (b) multiple regression analyses of relationships between fitness and risk factors showed that fitter subjects had better risk profiles than less fit. Longitudinal analyses including (a) comparisons of risk factor changes in subjects grouped as fitness "losers", "stable", "small gain", and "large gain", and (b) multiple regression analyses of relationships between fitness change and risk factor changes showed that fitness change was largely unrelated to risk factor changes. The study supported the existence of beneficial associations between fitness and risk factors but not cause and effect relationships.
Sedgwick
A W
AW
Institute for Fitness Research and Training Inc., Adelaide, Australia.
Thomas
D W
DW
Davies
M
M
Baghurst
K
K
Rouse
I
I
D000328:Adult; D001315:Australia; D001794:Blood Pressure; D003327:Coronary Disease / Q000209:etiology / Q000503:physiopathology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D010809:Physical Fitness; D012307:Risk Factors; D012959:Socioeconomic Factors; D014280:Triglycerides / Q000097:blood
D014280:Triglycerides