title: [Dynamics of blood serotonin contents in acute disorders of cerebral circulation and circulatory encephalopathy].
abstract: Blood serotonin levels have been measured by spectrofluorometry in 145 patients with various manifestations of acute disorders of the cerebral circulation (ADCC): with ischemic stroke, cerebral hypertensive crises, transient impairments of the cerebral circulation, and with circulatory encephalopathy (DE) in the presence of arterial hypertension combined with atherosclerosis. In ADCC patients the blood serotonin has been measured 7 times, in DE ones 3 times. This level has been found changed in the patients with ischemic stroke and with cerebral hypertensive crises for a long time after the cerebral circulation impairment. Serotonin levels correlated with the condition severity and course in ADCC and DE. The vestibulocerebellar syndrome in DE has been treated more effectively, particularly with trental. The blood serotonin level may be regarded as a prognostic criterion of the disease outcome and of the treatment efficacy.
authors: E V
authors: EV
authors: Khrapova
authors: N V
authors: NV
authors: Lebedeva
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001927:Brain Diseases / Q000097:blood* / Q000188:drug therapy / Q000209:etiology; D002561:Cerebrovascular Disorders / Q000097:blood*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D002537:Intracranial Arteriosclerosis / Q000150:complications; D008297:Male; D008875:Middle Aged; D010431:Pentoxifylline / Q000627:therapeutic use; D011379:Prognosis; D012701:Serotonin / Q000097:blood*
chemical_list: D012701:Serotonin; D010431:Pentoxifylline
vernacular_title: Dinamika soderzhaniia serotonina v krovi pri ostrykh narusheniiakh mozgovogo krovoobrashcheniia i distsirkuliatornoĭ éntsefalopatii.