[The role of the dopaminergic component in the autoregulatory reaction of the cerebral vessels].
Cerebral blood flow was measured in anesthetised white rats with the hydrogen clearance technique under different levels of arterial blood pressure before and after cerebral ischemia induced with the occlusion of the common carotid arteries during 12 min. The continuous i.v. infusion of dopamine improved the autoregulation of the cerebral blood flow in intact animals and restored it to the initial level in the rats with ischemia.
Gaevyĭ
M D
MD
Pchelintseva
T R
TR
Vereshchagin
V K
VK
Migruev
R R
RR
D000818:Animals; D001783:Blood Flow Velocity / Q000187:drug effects / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D002536:Cerebral Arteries / Q000187:drug effects / Q000502:physiology*; D002550:Cerebral Veins / Q000187:drug effects / Q000502:physiology*; D002560:Cerebrovascular Circulation / Q000187:drug effects / Q000502:physiology; D004298:Dopamine / Q000494:pharmacology / Q000502:physiology; D006706:Homeostasis / Q000187:drug effects / Q000502:physiology*; D002546:Ischemic Attack, Transient / Q000503:physiopathology; D051381:Rats; D011954:Receptors, Dopamine / Q000187:drug effects / Q000502:physiology*
D011954:Receptors, Dopamine; D004298:Dopamine
Rol' dofaminergicheskogo komponenta v autoreguliatornykh reaktsiiakh mozgovykh sosudov.