Evidence for a relationship between longevity of mammalian species and a lens growth parameter.
The lens growth was studied in a number of curves representing 16 mammalian species. Emphasis was placed on determining the length of the lens development stage. All the lens curves studied went through a growth crisis: It is a period of apparent growth slowing down, lasting linear during the resting lifespan (adult stage). The growth crisis occurred at a length that was characteristic for the species and was shown to be directly correlated with the species maximum lifespan potential. These results may indicate the prevalence of a common functional basis regulating the lens growth and thus operating in the longevity of mammalian species.
Tréton
J
J
Centre de Gérontologie Association Claude-Bernard, INSERM U.118, Paris, France.
Courtois
Y
Y
D000818:Animals; D001835:Body Weight; D001921:Brain / Q000033:anatomy & histology; D002417:Cattle; D004285:Dogs; D006133:Growth Substances / Q000502:physiology; D006168:Guinea Pigs; D006801:Humans; D007908:Lens, Crystalline / Q000033:anatomy & histology / Q000254:growth & development*; D008136:Longevity / Q000502:physiology*; D008322:Mammals / Q000033:anatomy & histology / Q000254:growth & development / Q000502:physiology*; D051379:Mice; D009929:Organ Size; D011817:Rabbits; D051381:Rats
D006133:Growth Substances