Stannous ion-induced tetanic contraction of the frog sartorius muscle.
Present study was conducted to elucidate the mechanism of twitch augmentation by stannous ion. Stannous ion increased the amplitude of the endplate potential and moreover, generated repetitive firing of the muscle fiber. These findings suggest that the twitch augmentation by stannous ion may be due not only to recruitment of the muscle fibers but also to a brief tetanic contraction of the individual fibers.
Hattori
T
T
Department of Dental Pharmacology, Matsumoto Dental College, Shiojiri, Japan.
Maehashi
H
H
D000818:Animals; D004558:Electric Stimulation; D066298:In Vitro Techniques; D009045:Motor Endplate / Q000187:drug effects; D009119:Muscle Contraction / Q000187:drug effects; D009132:Muscles / Q000187:drug effects*; D011892:Rana catesbeiana; D014001:Tin / Q000494:pharmacology*; D017971:Tin Compounds
D017971:Tin Compounds; C023599:stannous chloride; D014001:Tin