[Antibiotic prophylaxis in non-elective cesarean section with single-dose imipenem versus multiple-dose cefotaxime].
Antibiotic prophylaxis reduces the incidence of febrile morbidity in women undergoing non-elective cesarean section. A randomized comparison of prophylactic single dose Imipenem, a carbapenem antibiotic with the broadest antimicrobial spectrum of activity of any antibiotic, with multiple doses Cefotaxime, a third generation cephalosporin, was undertaken in 48 women who underwent non-elective cesarean section (22 receiving Imipenem, 26 Cefotaxime). The incidence of febrile morbidity in the Imipenem group was 4.54% versus 7.69 in patients receiving multiple doses of Cefotaxime. There were non serious complications in the treated groups.
Mansueto
G B
GB
Tomaselli
F
F
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002439:Cefotaxime / Q000008:administration & dosage / Q000627:therapeutic use*; D002585:Cesarean Section; D005260:Female; D006801:Humans; D015378:Imipenem / Q000008:administration & dosage / Q000627:therapeutic use*; D011247:Pregnancy; D011292:Premedication; D013530:Surgical Wound Infection / Q000517:prevention & control*
D000900:Anti-Bacterial Agents; D015378:Imipenem; D002439:Cefotaxime
Profilassi antibiotica in pazienti sottoposte a taglio cesareo non di elezione con imipenem in "single dose" versus cefotaxime in "multiple doses".