Ciprofloxacin versus amoxycillin/clavulanic acid in the treatment of urinary tract infections in general practice.
An open, randomized general practice study was performed to assess the comparative efficacy and tolerability of ciprofloxacin and amoxycillin/clavulanic acid in the treatment of uncomplicated urinary tract infection. One hundred and eighty nine patients were recruited into the study. In comparison of pre- and post-treatment urine cultures and symptomatology, ciprofloxacin was significantly more effective (P less than 0.01) than amoxycillin/clavulanic acid. Both drugs were well tolerated with minimal adverse side effects. Ciprofloxacin is an effective and safe treatment for uncomplicated urinary tract infection in general practice.
Abbas
A M
AM
Microbiology Department, Rotherham District General Hospital, Newbury, UK.
Chandra
V
V
Dongaonkar
P P
PP
Goel
P K
PK
Kacker
P
P
Patel
N A
NA
Shrivastava
O P
OP
Thakkar
B
B
Tillotson
G S
GS
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000658:Amoxicillin / Q000627:therapeutic use*; D002939:Ciprofloxacin / Q000627:therapeutic use*; D019818:Clavulanic Acid; D002969:Clavulanic Acids / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011897:Random Allocation; D014552:Urinary Tract Infections / Q000188:drug therapy*
D002969:Clavulanic Acids; D019818:Clavulanic Acid; D002939:Ciprofloxacin; D000658:Amoxicillin