title: Ciprofloxacin versus amoxycillin/clavulanic acid in the treatment of urinary tract infections in general practice.
abstract: An open, randomized general practice study was performed to assess the comparative efficacy and tolerability of ciprofloxacin and amoxycillin/clavulanic acid in the treatment of uncomplicated urinary tract infection. One hundred and eighty nine patients were recruited into the study. In comparison of pre- and post-treatment urine cultures and symptomatology, ciprofloxacin was significantly more effective (P less than 0.01) than amoxycillin/clavulanic acid. Both drugs were well tolerated with minimal adverse side effects. Ciprofloxacin is an effective and safe treatment for uncomplicated urinary tract infection in general practice.
authors: Microbiology Department, Rotherham District General Hospital, Newbury, UK.
authors: A M
authors: AM
authors: Abbas
authors: V
authors: V
authors: Chandra
authors: P P
authors: PP
authors: Dongaonkar
authors: P K
authors: PK
authors: Goel
authors: P
authors: P
authors: Kacker
authors: N A
authors: NA
authors: Patel
authors: O P
authors: OP
authors: Shrivastava
authors: B
authors: B
authors: Thakkar
authors: G S
authors: GS
authors: Tillotson
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000658:Amoxicillin / Q000627:therapeutic use*; D002939:Ciprofloxacin / Q000627:therapeutic use*; D019818:Clavulanic Acid; D002969:Clavulanic Acids / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011897:Random Allocation; D014552:Urinary Tract Infections / Q000188:drug therapy*
chemical_list: D002969:Clavulanic Acids; D019818:Clavulanic Acid; D002939:Ciprofloxacin; D000658:Amoxicillin