Blood coagulation profile in long-term hormone replacement therapy with mestranol.
The coagulation profile of oophorectomised women on long-term (15 yr) hormone replacement therapy with mestranol (30 micrograms/day) is compared to that of women on long-term placebo. Analysis of these data showed no significant difference in prothrombin time, partial thromboplastin time or in anti-thrombin III level in these groups.
Al-Azzawi
F
F
Department of Obstetrics and Gynaecology, Stobhill General Hospital, Glasgow, U.K.
Smith
D
D
Parkin
D
D
Hart
D M
DM
Lindsay
R
R
D000328:Adult; D001777:Blood Coagulation / Q000187:drug effects*; D003430:Cross-Sectional Studies; D005260:Female; D005342:Fibrinolysis / Q000187:drug effects; D006801:Humans; D008656:Mestranol / Q000627:therapeutic use*; D008875:Middle Aged; D010052:Ovariectomy; D010314:Partial Thromboplastin Time; D011446:Prospective Studies; D011517:Prothrombin Time; D011897:Random Allocation; D013997:Time Factors
D008656:Mestranol