Atypical cutaneous lymphoproliferative disorder resembling mycosis fungoides in AIDS. Report of a case with concurrent Kaposi's sarcoma.
A variety of neoplastic disorders have been described in patients with AIDS. Kaposi's sarcoma is the most common neoplasm and is recognized as one of the diagnostic criteria for AIDS. Unusual mucocutaneous carcinomas have also been reported in these patients, as have a variety of lymphoid neoplasms, including Hodgkin's and non-Hodgkin's lymphomas (NHLs). The NHLs that occur in AIDS patients are usually of B-cell or non-B, non-T-cell phenotype. In contrast, T-cell lymphomas have only rarely been reported in this patient population. We present the clinical, morphologic, and immunologic features of an atypical, cutaneous lymphoproliferative disorder resembling mycosis fungoides that developed in a 28-year-old homosexual man with AIDS and disseminated mucocutaneous Kaposi's sarcoma.
Longacre
T A
TA
Department of Pathology, University of New Mexico, Albuquerque.
Foucar
K
K
Koster
F
F
Burgdorf
W
W
D000163:Acquired Immunodeficiency Syndrome / Q000473:pathology*; D000328:Adult; D001344:Autopsy; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000473:pathology*; D008297:Male; D009182:Mycosis Fungoides / Q000473:pathology*; D012514:Sarcoma, Kaposi / Q000473:pathology*; D012871:Skin Diseases / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*; D013601:T-Lymphocytes / Q000473:pathology