title: Sedation during spinal anaesthesia: a case for the routine administration of oxygen.
abstract: We have studied the effect of sedation with midazolam on arterial oxygen saturation during spinal anaesthesia in two groups of patients: one group received supplementary oxygen, the other group breathed room air. A significant reduction in oxygen saturation was observed in patients not receiving supplementary oxygen; six of 15 patients in this group developed hypoxaemia or severe hypoxaemia which was corrected immediately by administration of oxygen. There were no episodes of hypoxaemia in any patient in the group receiving supplementary oxygen. It is concluded that oxygen should be administered routinely to patients receiving sedatives during spinal anaesthesia.
authors: Department of Anaesthetics, Plymouth General Hospital.
authors: A R
authors: AR
authors: Manara
authors: D C
authors: DC
authors: Smith
authors: C
authors: C
authors: Nixon
mesh_terms: D000368:Aged; D000775:Anesthesia, Spinal; D006801:Humans; D006993:Hypnotics and Sedatives / Q000494:pharmacology*; D007432:Intraoperative Period; D008297:Male; D008874:Midazolam / Q000494:pharmacology*; D010100:Oxygen / Q000097:blood* / Q000627:therapeutic use; D011897:Random Allocation; D013997:Time Factors
chemical_list: D006993:Hypnotics and Sedatives; D008874:Midazolam; D010100:Oxygen