[Brain structure and brain function in anorexia nervosa: a computerized tomography study].
Cranial computed tomography (CT) was performed in 12 patients with anorexia nervosa revealing that the majority of the patients displayed ventricular dilatation and/or sulcal widening. In six patients re-examined these structural brain alterations showed a strong trendency towards normalization after weight gain. With the intention of finding a functional correlate of the CT abnormalities, the regional cerebral blood flow (rCBF) was measured at admission and once again after weight gain and compared with the flow rates of a healthy control group. The mean flow rates assessed at the first examination did not significantly differ from those assessed at the second examination and from those of a control group. Thus, despite the CT findings of structural brain abnormalities, the measurement of the regional cerebral blood flow gave no hint of a reduced functioning of certain brain areas in anorexia nervosa.
Krieg
J C
JC
Lauer
C
C
Leinsinger
G
G
Schreiber
W
W
Pirke
K M
KM
D000293:Adolescent; D000328:Adult; D000856:Anorexia Nervosa / Q000175:diagnosis*; D001925:Brain Damage, Chronic / Q000175:diagnosis*; D002540:Cerebral Cortex / Q000473:pathology; D002552:Cerebral Ventricles / Q000473:pathology; D002560:Cerebrovascular Circulation; D006801:Humans; D008297:Male; D019965:Neurocognitive Disorders / Q000175:diagnosis*; D009483:Neuropsychological Tests; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed
Hirnstruktur und Hirnfunktion bei Anorexia nervosa: eine computertomographische Untersuchung.