title: Acute myelocytic leukemia and prior allergies.
abstract: The relationship between prior allergies and adult acute myelocytic leukemia was investigated in a population-based case-control study. Based on data from personal interviews of 98 cases and 133 controls, a history of any type of allergy was associated with a significantly decreased risk of acute myelocytic leukemia (OR = 0.35, 95% CI = 0.20-0.60). Risk declined with the total number of specific allergies reported (p less than 0.001), and was reduced in relation to a history of prior asthma, eczema and hives. The implications of these findings in relation to natural immune surveillance against developing neoplasms are discussed.
authors: Division of Epidemiology, University of Minnesota, Minneapolis 55455.
authors: R K
authors: RK
authors: Severson
authors: S
authors: S
authors: Davis
authors: D B
authors: DB
authors: Thomas
authors: R G
authors: RG
authors: Stevens
authors: L
authors: L
authors: Heuser
authors: L E
authors: LE
authors: Sever
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000150:complications*; D015470:Leukemia, Myeloid, Acute / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D012042:Registries; D012306:Risk; D014861:Washington / Q000453:epidemiology