BGP (osteocalcin, bone-Gla-protein) in involutional osteoporosis.
The role of BGP (osteocalcin) as bone marker in the study and management control of involutional osteoporosis is emphasized and the different radioimmunoassays and their limitations are commented. Our results showed significantly lower sBGP levels in osteoporotic patients compared with control group and a positive linear correlation was found between sBGP and serum alkaline phosphatase but no correlation was obtained with urinary hydroxyproline/creatinine ratio, serum tartrate-resistant acid phosphatase or bone mineral content measured by dual photon absorptiometry.
Rapado
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A
Unidad Metabólica, Fundación Jimenez Diaz, Madrid, Spain.
de la Piedra
C
C
Torres
R
R
D000135:Acid Phosphatase / Q000378:metabolism; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000469:Alkaline Phosphatase / Q000378:metabolism; D001842:Bone and Bones / Q000378:metabolism*; D002135:Calcium-Binding Proteins / Q000097:blood*; D003720:Densitometry; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000032:analysis; D008875:Middle Aged; D008903:Minerals / Q000032:analysis; D015675:Osteocalcin; D010024:Osteoporosis / Q000378:metabolism*
D002135:Calcium-Binding Proteins; D008903:Minerals; D015675:Osteocalcin; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase