[Cardio- and hemodynamics of dogs during the development of postischemic shock reaction].
Experiments on dogs have shown that tension of peripheral capacitive vessels decreased and development of the blood deposition reaction in the venous part of the vascular bed occurred immediately after beginning of long-ischemized tissue perfusion. This leads to limitation of venous blood return to the heart, decrease of the cardiac output and development of the system hypotension. Lowering in the perfusion coronary pressure induced limitation of the coronary blood flow and inhibition of the myocardial contractility. Indicated constriction of resistive vessels and dilatation of the capacitive ones may be due to an increase of the prostacyclin and thromboxane A2 blood levels. Described disturbances achieved their maximum 3 hours later and were accompanied by arterial hypoxemia, metabolic acidosis and hypercapnia.
Sagach
V F
VF
Dmitrieva
A V
AV
D015121:6-Ketoprostaglandin F1 alpha / Q000097:blood; D000818:Animals; D001784:Blood Gas Analysis; D004285:Dogs; D006321:Heart / Q000503:physiopathology*; D006439:Hemodynamics; D006614:Hindlimb / Q000098:blood supply*; D006863:Hydrogen-Ion Concentration; D007511:Ischemia / Q000097:blood / Q000150:complications / Q000503:physiopathology*; D010313:Partial Pressure; D015424:Reperfusion; D012769:Shock / Q000097:blood / Q000209:etiology / Q000503:physiopathology*; D013929:Thromboxane B2 / Q000097:blood; D013997:Time Factors
D013929:Thromboxane B2; D015121:6-Ketoprostaglandin F1 alpha
Kardio- i gemodinamika u sobak pri razvitii postishemicheskoĭ shokovoĭ reaktsii.