Pulmonary actinomycosis in a patient with HIV infection.
Pulmonary actinomycosis is a rare clinical entity. It may arise primarily from aspiration of infected oropharyngeal material or secondarily from contiguous spread of cervicofacial or abdominal infection. We report the case of an HIV-seropositive patient with a two-week history of fever, a productive cough, and pleuritic chest pain. Chest x-ray revealed bilateral patchy alveolar infiltrates. Histological examination of transbronchial biopsy specimens revealed acute inflammation and granules with radiating gram-positive filaments with clubbed ends consistent with actinomycosis. The patient responded to intravenous penicillin and is currently well on long-term enteral antibiotic therapy.
Klapholz
A
A
Talavera
W
W
Rorat
E
E
Salsitz
E
E
Widrow
C
C
D000190:Actinomyces / Q000302:isolation & purification; D000196:Actinomycosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D000328:Adult; D006679:HIV Seropositivity / Q000150:complications* / Q000473:pathology; D006801:Humans; D007262:Infusions, Intravenous; D008171:Lung Diseases / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008297:Male; D010400:Penicillin G / Q000008:administration & dosage / Q000627:therapeutic use
D010400:Penicillin G