Hypoxaemia after inhalation of 50% nitrous oxide and oxygen.
We have investigated, in volunteers, the effect of inhaling 50% nitrous oxide in oxygen on subsequent oxygenation. Subjects breathed either 50% nitrous oxide in oxygen or 50% nitrogen in oxygen during hyperventilation and normal ventilation. Arterial oxygen saturation and end-expired oxygen concentrations were lower after 50% nitrous oxide in oxygen than after the other mixture with both patterns of ventilation and were lowest after hyperventilation with 50% nitrous oxide in oxygen.
Wilkins
C J
CJ
University Department of Anaesthesia, Royal Infirmary, Leicester.
Reed
P N
PN
Aitkenhead
A R
AR
D000280:Administration, Inhalation; D000328:Adult; D005260:Female; D006801:Humans; D006985:Hyperventilation / Q000097:blood; D008297:Male; D009609:Nitrous Oxide / Q000494:pharmacology*; D010100:Oxygen / Q000097:blood / Q000494:pharmacology*; D013997:Time Factors
D009609:Nitrous Oxide; D010100:Oxygen