title: LL-E19020 alpha and beta, animal growth promoting antibiotics: taxonomy, fermentation and biological activity.
abstract: Antibacterial antibiotics LL-E19020 alpha and beta were isolated from the fermentation broth of an actinomycete strain. Based on cultural and physiological characteristics, culture LL-E19020 was identified as a new subspecies of Streptomyces lydicus. The LL-E19020 alpha and beta antibiotics were found to possess a very narrow antibacterial spectrum against human pathogens. In studies in chickens, LL-E19020 alpha demonstrated excellent growth promoting activity.
authors: Medical Research Division, American Cyanamid Company, Lederle Laboratory, Pearl River, New York 10965.
authors: W M
authors: WM
authors: Maiese
authors: M P
authors: MP
authors: Lechevalier
authors: H A
authors: HA
authors: Lechevalier
authors: J
authors: J
authors: Korshalla
authors: J
authors: J
authors: Goodman
authors: M J
authors: MJ
authors: Wildey
authors: N
authors: N
authors: Kuck
authors: S D
authors: SD
authors: Conner
authors: M
authors: M
authors: Greenstein
mesh_terms: D000617:Aminoglycosides; D000818:Animals; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D002645:Chickens; D002851:Chromatography, High Pressure Liquid; D005260:Female; D005285:Fermentation; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D006133:Growth Substances / Q000302:isolation & purification* / Q000494:pharmacology; D008297:Male; D051379:Mice; D013291:Streptococcus / Q000187:drug effects; D013302:Streptomyces / Q000145:classification / Q000378:metabolism
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D006133:Growth Substances; C058743:phenelfamycin F; C058741:phenelfamycin E