Genetics and the diagnosis of Alzheimer's disease: true signals and original din.
Diagnosis is a central problem in Alzheimer's research, including linkage studies in particular. The magnitude of expected diagnostic error, its likely effect on research, and way to minimize it, provides the focus of this commentary.
Heston
L L
LL
University of Minnesota, Department of Psychiatry, Medical School, Minneapolis 55455.
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000235:genetics; D006801:Humans