title: Haemophilus influenzae type b disease in the Oxford region.
abstract: A prospective survey of children in the Oxford region identified 200 cases of systemic Haemophilus influenzae type b disease in the first three and a half years of the study. The annual incidence in children less than 5 years of age was 33.4/100,000. This represents a cumulative incidence of one systemic infection in 600 children before their 5th birthday. The mortality was 5.0%. The risk of H influenzae type b meningitis was one in 850 with a mortality of 5.6%, and substantial morbidity among survivors. From the total live birth rate, about 1300 cases of systemic H influenzae type b disease, over 900 cases of H influenzae type b meningitis, and 65 deaths would be predicted annually in children in the United Kingdom.
authors: University Department of Paediatrics, John Radcliffe Hospital, Oxford.
authors: G
authors: G
authors: Tudor-Williams
authors: J
authors: J
authors: Frankland
authors: D
authors: D
authors: Isaacs
authors: R T
authors: RT
authors: Mayon-White
authors: J A
authors: JA
authors: MacFarlane
authors: M P
authors: MP
authors: Slack
authors: E
authors: E
authors: Anderson
authors: D G
authors: DG
authors: Rees
authors: E R
authors: ER
authors: Moxon
mesh_terms: D002648:Child; D002675:Child, Preschool; D004739:England; D006192:Haemophilus Infections / Q000453:epidemiology* / Q000401:mortality; D006193:Haemophilus influenzae; D006801:Humans; D007223:Infant; D008583:Meningitis, Haemophilus / Q000453:epidemiology / Q000401:mortality; D011446:Prospective Studies