Biochemical indicators related to antioxidant status and bone metabolic activity in Finnish elderly men.
Serum concentrations of vitamins A, D and E, osteocalcin, calcium, selenium, cholesterol and HDL-cholesterol were measured in 270 elderly Finnish men aged from 65 to 84 years. alpha-Tocopherol and selenium decreased with aging as did 25-hydroxyvitamin D. Low serum levels were found especially for 25-hydroxyvitamin D (19% less than 8 micrograms/l), selenium (45% less than 70 micrograms/l) and osteocalcin (52% less than 1.8 micrograms/l). Men living in institutions for the aged had lower serum 25-hydroxyvitamin D levels than those living at home. Smoking was associated with decreased and alcohol consumption with increased serum levels of 25-hydroxyvitamin D. Those men who reported having most weekly working hours had highest serum levels of 25-hydroxyvitamin D. Serum osteocalcin correlated with 25-hydroxyvitamin D at normal or high serum vitamin levels but not at low vitamin levels; neither did it correlate with age or consumption of tobacco, alcohol or multivitamin pills.
Mäenpää
P H
PH
Department of Biochemistry, University of Kuopio, Finland.
Pirhonen
A
A
Pirskanen
A
A
Pekkanen
J
J
Alfthan
G
G
Kivelä
S L
SL
Nissinen
A
A
D000368:Aged; D000369:Aged, 80 and over; D000975:Antioxidants / Q000097:blood*; D001842:Bone and Bones / Q000378:metabolism*; D002135:Calcium-Binding Proteins / Q000097:blood; D015331:Cohort Studies; D003327:Coronary Disease / Q000378:metabolism; D005387:Finland; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D015675:Osteocalcin; D012307:Risk Factors; D014807:Vitamin D / Q000097:blood
D000975:Antioxidants; D002135:Calcium-Binding Proteins; D015675:Osteocalcin; D014807:Vitamin D