Motor neuropathy with activity of monoclonal IgM antibody to GD1a ganglioside.
A patient with motor neuropathy associated with monoclonal IgM protein is reported. Using enzyme-linked immunosorbent assays, the antibody activity of the monoclonal IgM was shown to be directed against GD1a ganglioside, a new and so far unreported specificity.
Bollensen
E
E
Department of Neurology, University of Göttingen, Federal Republic of Germany.
Schipper
H I
HI
Steck
A J
AJ
D000368:Aged; D000911:Antibodies, Monoclonal / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005732:Gangliosides / Q000276:immunology*; D015417:Hereditary Sensory and Motor Neuropathy / Q000276:immunology*; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology*; D008297:Male
D000911:Antibodies, Monoclonal; D005732:Gangliosides; D007075:Immunoglobulin M