Amiodarone toxicity: recurrence of interstitial pneumonitis after withdrawal of the drug.
Amiodarone hydrochloride, an iodinated benzofuran derivative, is effective for treatment of supraventricular and ventricular arrhythmias. Pulmonary fibrosis has been reported after treatment with this drug. We present a patient with amiodarone pulmonary toxicity, who initially responded to corticosteroid therapy, but who developed a clinical relapse two months after withdrawal of the drug.
Parra
O
O
Department of Pneumology, Hospital Germans Trias i Pujol, Barcelona, Spain.
Ruiz
J
J
Ojanguren
I
I
Navas
J J
JJ
Morera
J
J
D000638:Amiodarone / Q000009:adverse effects* / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000188:drug therapy; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D011658:Pulmonary Fibrosis / Q000139:chemically induced* / Q000188:drug therapy; D012008:Recurrence
D000638:Amiodarone; D008775:Methylprednisolone