Antihypertensive treatment of the elderly in general practice.
In order to assess the antihypertensive care received by the elderly, where clear therapeutic guidelines are lacking, a population of 3,858 aged over 64 years was studied. Data were derived from a large Italian 'Study on Blood Pressure in the Elderly', carried out in general practice. Over 90% of the 2,059 known hypertensive patients were receiving drug treatment, with no age or sex-related differences. A single drug was prescribed to 50.2% of treated patients; only 5.5% were receiving three or more drugs. Diuretics and older sympatholytic agents were by far the most frequently prescribed categories, with four drugs (hydrochlorothiazide, amiloride, methyldopa and chlorthalidone) accounting for over 50% of all prescriptions. Low-dosage treatment schedules were frequently used, often associated with less-often-than-daily drug administration. Our study shows that physicians' attitudes to the treatment of arterial hypertension in the elderly are fairly uniform, with treatment of all subjects but with low drug dosages.
Villella
M
M
Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy.
Devoto
M A
MA
Avanzini
F
F
Alli
C
C
Bettelli
G
G
Colombo
F
F
Di Tullio
M
M
Marchioli
R
R
Mariotti
G
G
Radice
M
M
D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004232:Diuretics / Q000627:therapeutic use; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D010865:Pilot Projects; D013565:Sympatholytics / Q000627:therapeutic use
D000959:Antihypertensive Agents; D004232:Diuretics; D013565:Sympatholytics