[Magnetic resonance imaging of intracranial lesions of tuberous sclerosis].
Six patients with tuberous sclerosis were evaluated with computed cranial tomography (CCT) and magnetic resonance imaging (MRI). The results were assessed in comparison with the clinical severity of the disease. The brain lesions were shown by MRI as low-signal areas on IR images (T1 weighted sequences) and high-signal areas on SE images (T2 weighted sequences) Three patients, who had severe psychomotor retardation (DQ less than 70) and intractable epileptic seizures following infantile spasms, had many cortical and subcortical lesions. In the other three patients, intelligence was normal or slightly retarded (DQ or IQ greater than 70) and epileptic seizures were well controlled, and small subependymal lesions were observed. Cortical lesions were rare. These results indicate that MRI can detect more precisely intracranial lesions in tuberous sclerosis.
Shimoizumi
H
H
Miyao
M
M
Kobayashi
S
S
Nakamigawa
T
T
Yamamoto
Y
Y
Tanaka
O
O
Yanagisawa
M
M
D000293:Adolescent; D001921:Brain / Q000473:pathology*; D002648:Child; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D011379:Prognosis; D011596:Psychomotor Disorders / Q000175:diagnosis; D014402:Tuberous Sclerosis / Q000175:diagnosis / Q000473:pathology*