title: Chemical toxicology for the coroner.
abstract: Toxicology results from all 302 coroners' cases referred to the supraregional unit at Beaumont Hospital over the one year period December 1987 to November 1988 are detailed. Clinical details were provided in 69.5% and formed the basis for the formation of four groups; road traffic accidents, suicides, possible suicides and possible carbon monoxide poisonings. All tests reported were instigated by the referring pathologist on behalf of the coroner. Alcohol was measured in all except 11 patients and a positive result was found in 44%. Drug screens were performed in 68.5% of cases with a positive finding in 30%. At least one positive result was found in 61.9% of the total. In the 60.4% of 53 road accident victims where alcohol was found, the median value was 117 mg/dl. COHb was measured in 23 cases and the median saturation was 45%. There were 12 suicides and agents found included paraquat, CO, cyanide, pancuronium bromide, and amitriptyline. Alcohol levels greater than 120 mg/dl were present in seven. In the 22 cases of suspected suicide, 77.3% were positive for drugs and more than one substance was found in 45.4%.
authors: Department of Chemical Pathology, Beaumont Hospital, Dublin, Ireland.
authors: W P
authors: WP
authors: Tormey
authors: H
authors: H
authors: Crosse
authors: A
authors: A
authors: Pierce
mesh_terms: D000063:Accidents, Traffic; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002249:Carbon Monoxide Poisoning / Q000453:epidemiology / Q000378:metabolism; D002263:Carboxyhemoglobin / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D002855:Chromatography, Thin Layer; D003334:Coroners and Medical Examiners; D000431:Ethanol / Q000097:blood; D005260:Female; D005766:Gastrointestinal Contents / Q000032:analysis; D006801:Humans; D007223:Infant; D007494:Ireland; D008297:Male; D008875:Middle Aged; D004364:Pharmaceutical Preparations / Q000032:analysis; D011041:Poisoning / Q000175:diagnosis / Q000453:epidemiology*; D013056:Spectrophotometry, Ultraviolet; D013405:Suicide
chemical_list: D004364:Pharmaceutical Preparations; D000431:Ethanol; D002263:Carboxyhemoglobin