[The interrelationship between serotonin and lipid peroxidation products during experimental wound healing].
On 220 male Wistar rats with models of aseptic and contaminated skin wounds the authors studied interrelationship between serotonin and hydroperoxide in the wound tissues and the blood. A comparative analysis of the changes of these indices in the blood and tissues showed that the degree of these disorders on the 1st day after the operation was determined by operational trauma and with the development of purulent inflammation intensive initiation of lipoperoxidation products takes place.
Zakharov
V V
VV
Mamedov
L A
LA
Meshcheriakova
S A
SA
Shekhter
A B
AB
Kapitonov
N I
NI
D000818:Animals; D001207:Asepsis; D004353:Drug Evaluation, Preclinical; D006861:Hydrogen Peroxide / Q000378:metabolism; D007538:Isoniazid / Q000627:therapeutic use; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D008996:Monoamine Oxidase Inhibitors; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000378:metabolism; D013997:Time Factors; D014945:Wound Healing / Q000187:drug effects; D014946:Wound Infection / Q000188:drug therapy / Q000378:metabolism
D008996:Monoamine Oxidase Inhibitors; D012701:Serotonin; D006861:Hydrogen Peroxide; D013482:Superoxide Dismutase; D007538:Isoniazid
Vzaimosviaz' serotonina i produktov lipoperoksidatsii v protsesse zazhivleniia ran v éksperimente.