[Clinical effects of Juzendaiho-to on immunologic and fatty metabolic states in postoperative patients with gastrointestinal cancer].
Juzen-daiho-to is one of the Chinese traditional medicines which is usually applied with patients suffering from anemia or chronic exhaustive disease. Twenty-three patients after gastrectomy and 16 patients after colectomy were studied for NK cell activity, blastogenesis by PHA, several T-lymphocyte subsets, serum triglyceride and serum lipo-protein before drug administration at one, three, six, nine months and one year after the start of drug administration respectively. A remarkable elevation in NK cell activity was noted 3 and 6 months after the drug administration. Statistical analysis shows a significant converse correlation between NK cell activity and lipo-protein value in the group given Juzendaiho-to.
Okamoto
T
T
Dept. of Surgery, Kanagawa Cancer Center Hospital.
Motohasi
H
H
Takemiya
S
S
Sugimasa
Y
Y
Sairenji
M
M
Kobayasi
S
S
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004435:Eating / Q000187:drug effects; D005770:Gastrointestinal Neoplasms / Q000276:immunology* / Q000378:metabolism / Q000601:surgery; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007694:Killer Cells, Natural / Q000276:immunology; D050356:Lipid Metabolism; D008074:Lipoproteins / Q000097:blood; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D011184:Postoperative Period; D013601:T-Lymphocytes / Q000145:classification; D014280:Triglycerides / Q000097:blood
D004365:Drugs, Chinese Herbal; D008074:Lipoproteins; D014280:Triglycerides