title: Chronic ethanol ingestion selectively affects memory modulation in rats.
abstract: Post-training treatment alters memory by different mechanisms. Naloxone enhances memory by antagonism of endogenous beta-endorphin-induced state dependency. Epinephrine facilitates consolidation at low doses and generates state dependency at high doses. Exposure to a session of tones causes retroactive interference through a cognitive effect. The present data show that chronic ethanol ingestion, in rats, inhibited the post-training effect of naloxone and of a high dose of epinephrine on the retention of an inhibitory avoidance task but did not inhibit retrograde interference by a session of tones or retrograde facilitation by a low dose of epinephrine. Therefore, ethanol appears to selectively affect post-training influences related to state dependency.
authors: Departamento de Bioquímica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil.
authors: C
authors: C
authors: Dalmaz
authors: C
authors: C
authors: Fin
authors: C B
authors: CB
authors: Oliveira
authors: I
authors: I
authors: Izquierdo
mesh_terms: D000818:Animals; D001362:Avoidance Learning; D001835:Body Weight / Q000187:drug effects; D004326:Drinking; D004924:Escape Reaction / Q000187:drug effects; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D008568:Memory; D051381:Rats; D011919:Rats, Inbred Strains; D012153:Retention, Psychology / Q000187:drug effects*
chemical_list: D000431:Ethanol