title: Asymmetric somatosensory activation with right- vs left-hand stimulation: a positron emission tomographic study.
abstract: Metabolic activation of the right and left somatosensory cortices (SSC) in response to an active sensorimotor task (palpation and sorting of mah jongg tiles) was studied in 16 right-handed normal volunteers using positron emission tomography (PET) and a double-injection [18F]fluorodeoxyglucose strategy. In 8 subjects with right-hand stimulation, cerebral metabolic rate for glucose (CMRglc) in the contralateral SSC increased by 16.7 +/- 5.1% (mean +/- S.D.); the increase in the ipsilateral SSC was 4.8 +/- 3.2%. In contrast, in the 8 subjects with left-hand stimulation, the contralateral increase was 12.0 +/- 2.9% and the ipsilateral increase was 5.9 +/- 1.5%. Thus, contralateral SSC activation was significantly higher with stimulation of the right hand, while the ipsilateral/contralateral symmetry of activation was greater when the left hand was stimulated.
authors: Department of Neurology, University of Miami School of Medicine, FL 33101.
authors: F
authors: F
authors: Yoshii
authors: M D
authors: MD
authors: Ginsberg
authors: R E
authors: RE
authors: Kelley
authors: J Y
authors: JY
authors: Chang
authors: W W
authors: WW
authors: Barker
authors: G
authors: G
authors: Ingenito
authors: A M
authors: AM
authors: Apicella
authors: M Y
authors: MY
authors: Globus
authors: R
authors: R
authors: Duara
authors: T E
authors: TE
authors: Boothe
mesh_terms: D000328:Adult; D000368:Aged; D003837:Deoxy Sugars; D003847:Deoxyglucose / Q000031:analogs & derivatives / Q000378:metabolism; D005260:Female; D019788:Fluorodeoxyglucose F18; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013003:Somatosensory Cortex / Q000000981:diagnostic imaging / Q000378:metabolism / Q000502:physiology*; D014055:Tomography, Emission-Computed
chemical_list: D003837:Deoxy Sugars; D019788:Fluorodeoxyglucose F18; D003847:Deoxyglucose