Persistent CSF leucocytosis associated with intrathecal gentamycin.
A case where the administration of intrathecal gentamycin, used to treat a ventriculitis consequent upon a ventriculoperitoneal shunt infection, with a persistent elevation of the CSF leucocyte count is described. In a situation where the number of white cells in the CSF is taken to indicate resolution of infection, it is important to recognise that apparent failure of resolution of infection may be due to the gentamycin itself and not persistent infection.
Lee
T K
TK
Nuffield Department of Neurosurgery, Radcliffe Infirmary, Oxford, United Kingdom.
Kerr
R S
RS
Adams
C B
CB
D001927:Brain Diseases / Q000188:drug therapy*; D002557:Cerebrospinal Fluid Shunts / Q000009:adverse effects*; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007278:Injections, Spinal; D007710:Klebsiella Infections / Q000188:drug therapy*; D007964:Leukocytosis / Q000139:chemically induced*
D005839:Gentamicins