Second genetic polymorphism of tear proteins in the rat (Rtp-2).
Electrophoresis of tear proteins on agarose gel showed polymorphism in the fastest migrating protein among 32 inbred strains of rats. In 8 strains, the protein was missing (RTP-2 B), while the other strains expressed the protein (RTP-2 A). The trait was found to be controlled by a single autosomal locus. The designation Rtp-2 locus, with two alleles (Rtp-2a, Rtp-2b), is tentatively proposed. The Rtp-2 locus is loosely linked to c locus, with a recombination frequency of 36.7 +/- 5.4 percent.
Kondo
Y
Y
Institute of Laboratory Animals, Faculty of Medicine, Kyoto University, Japan.
Hamada
S
S
Serikawa
T
T
Yamada
J
J
D000818:Animals; D002874:Chromosome Mapping; D004587:Electrophoresis, Agar Gel; D005136:Eye Proteins / Q000032:analysis / Q000235:genetics*; D006801:Humans; D051379:Mice; D011110:Polymorphism, Genetic; D051381:Rats; D013666:Tears / Q000032:analysis*
D005136:Eye Proteins; C042434:tear proteins