Effects of magnetic resonance imaging (MRI) on the formation of mouse dentin and bone.
The effects of magnetic resonance imaging (MRI) on dentin and bone formation in mice were examined using standard autoradiographic and liquid scintillation procedures. It was observed that exposure to a standard 23.2 min clinical multislice MRI (0.15T) procedure caused a significant increase in the synthesis of the collagenous matrix of dentin in the incisors of mice. There were no significant effects on alveolar and tibial bone matrix synthesis. These results suggest that the magnetic fields associated with MRI can affect the activity of cells and/or tissues that are involved in rapid synthetic activity.
Kwong-Hing
A
A
Division of Oral Biology, University of Western Ontario, London, Canada.
Sandhu
H S
HS
Prato
F S
FS
Frappier
J R
JR
Kavaliers
M
M
D000818:Animals; D001345:Autoradiography; D003094:Collagen / Q000096:biosynthesis*; D003810:Dentinogenesis; D008279:Magnetic Resonance Imaging; D008297:Male; D051379:Mice; D010012:Osteogenesis; D012588:Scintillation Counting
D003094:Collagen