Changes in monoamines and their metabolite levels in substantia nigra of aged rats.
A decrease in the monoamine and monoamine metabolite contents in the substantia nigra of aged rats vs. controls has been found. Hence, it can be speculated that this decrease may play a role in the multiple alterations in dopaminergic functions observed in aged rats.
Venero
J L
JL
Departmento de Bioquimica, Facultad de Farmacia, Sevilla, Spain.
Machado
A
A
Cano
J
J
D000367:Age Factors; D000818:Animals; D015306:Biogenic Monoamines / Q000378:metabolism*; D004298:Dopamine / Q000378:metabolism; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013378:Substantia Nigra / Q000378:metabolism*
D015306:Biogenic Monoamines; D004298:Dopamine