Monozygotic twins discordant for Alzheimer's disease.
We identified 3 pairs of monozygotic twins discordant for probable Alzheimer's disease from a twin register and found no systematic differences in potential risk factor exposures between affected and unaffected twins. Such cases predict a role for environmental factors in the etiology or clinical onset of Alzheimer's disease.
Creasey
H
H
Department of Geriatric Medicine, University of Sydney, NSW, Australia.
Jorm
A
A
Longley
W
W
Broe
G A
GA
Henderson
A S
AS
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000235:genetics* / Q000523:psychology; D004200:Diseases in Twins; D005260:Female; D006801:Humans; D008297:Male; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors; D014427:Twins / Q000235:genetics*; D014430:Twins, Monozygotic / Q000235:genetics*