Retrospective analysis of 97 patients with infective endocarditis seen over the past 8 years.
The medical records of 97 consecutive patients (101 episodes) of infective endocarditis seen from January 1979 through January 1987 were reviewed. Only 30% of the patients were over 50 years of age and the majority (69%) of infecting organisms were streptococci (mainly of the viridans group), which were similar to those reported from the West in the early antibiotic era. Pseudomonas organisms and enterococci accounted for 6% and 5%, respectively. Fungal infections were noted in 2 patients. There was a high incidence (38%) of predisposing rheumatic valvular disease; approximately half of these patients had prosthetic valve infections. Mitral valve prolapse was also an important predisposing disease (11%). One-third (34%) of the patients had febrile illness for longer than 8 weeks before the diagnosis was established. The hospital morality rate was 22%; cerebral embolism and ruptured mycotic aneurysm, congestive heart failure, and sudden death were the major causes of death. Echocardiography disclosed vegetations on the cardiac valves and preexisting lesions in 75% of the episodes. Early recognition and proper treatment should be the focus of efforts to reduce mortality from infective endocarditis.
Cheng
J J
JJ
Ko
Y L
YL
Chang
S C
SC
Lien
W P
WP
Tseng
Y Z
YZ
Lee
Y T
YT
Hsieh
Y Y
YY
Hsieh
W C
WC
Wu
M C
MC
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D004452:Echocardiography; D004697:Endocarditis, Bacterial / Q000209:etiology / Q000382:microbiology / Q000401:mortality; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008945:Mitral Valve Prolapse / Q000150:complications; D011379:Prognosis; D012189:Retrospective Studies; D012214:Rheumatic Heart Disease / Q000150:complications; D013290:Streptococcal Infections; D013624:Taiwan; D013997:Time Factors