[T-cell lymphoma associated with sprue].
A 47-year-old woman, known to have coeliac disease, developed bouts of fever, up to 39 degrees C, with loss of weight and treatment-resistant diarrhoea, as well as swelling of the submandibular, axillary and inguinal lymph nodes. Tests revealed a pancytopenia (haemoglobin 8.8 g/dl, leucocytes 500/microliter, platelets 19,000/microliter), and a reduction of the Quick value to 39%. Computer tomography demonstrated extensive abdominal lymphomas. The patient's general condition quickly deteriorated, hypoproteinaemia developed (total protein 4.6 g/dl) with peripheral oedema, ascites and pleural effusion. She died before the suspected diagnosis of coeliac disease-associated malignant lymphoma could be confirmed. Autopsy demonstrated a highly malignant, pleomorphic, primary abdominal non-Hodgkin lymphoma, immunohistologically a T-cell lymphoma.
Ormann
W
W
Medizinische Klinik, Burgfeldkrankenhauses, Kassel.
Hirschmann
W D
WD
Alexandrakis
E
E
Bauerle
H
H
D000008:Abdominal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D002446:Celiac Disease / Q000150:complications*; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008875:Middle Aged; D013601:T-Lymphocytes; D014057:Tomography, X-Ray Computed
Sprue-assoziiertes T-Zell-Lymphom.