The role of milk and lactose intolerance in Ethiopian patients with non-ulcer dyspepsia: a case control study.
Milk intolerance, lactose intolerance and non-ulcer dyspepsia are common among Ethiopians. This study, therefore, was designed to find out if milk intolerance associated with lactase deficiency account for non-ulcer dyspepsia. Ninety-eight patients with non-ulcer dyspepsia and 95 controls were examined and interviewed for demographic data and milk drinking habits. Then each had a lactose tolerance test (LTT), stool examination for pH, ova and parasites. The demographic characteristics and the number of milk drinkers were comparable in the 2 groups. However, milk intolerance and lactose intolerance were significantly higher among the patients with non-ulcer dyspepsia than among the control group (p less than 0.01, p less than 0.05 respectively). The combination of milk intolerance, lactose intolerance and LTT was also significantly different (p less than 0.01). The mean stool pH was markedly reduced after lactose ingestion and there were more ova and parasites in the stools of the control group. These observations suggest that milk intolerance and/or lactose intolerance account significantly for the symptoms of the patients with non-ulcer dyspepsia. However, since lactose intolerance and abnormal LTT are very common among adult Ethiopians symptoms related to the drinking of milk should be interpreted with caution vis-a-vis the results of the lactose loading test.
Tsega
E
E
Endeshaw
Y
Y
Mengesha
B
B
Tedla
B
B
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D003430:Cross-Sectional Studies; D004415:Dyspepsia / Q000209:etiology*; D005002:Ethiopia; D005260:Female; D006801:Humans; D007787:Lactose Intolerance / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D008892:Milk / Q000009:adverse effects*