Use of serum squamous cell carcinoma antigen assays in chemotherapy treatment of cervical cancer.
Serum squamous cell carcinoma antigen levels of 15 patients with recurrent or progressive squamous cell carcinoma of the cervix on chemotherapy treatment were assayed. In 13 of these 15 patients (86.7%), clinical response was positive correlated with change in serum SCC level. A stationary or rising serum SCC level indicated that the disease is probably stationary or progressive and chemotherapy should be stopped or changed.
Ngan
H Y
HY
Department of Obstetrics and Gynaecology, University of Hong Kong.
Wong
L C
LC
Chan
S Y
SY
Ma
H K
HK
D000328:Adult; D000368:Aged; D000951:Antigens, Neoplasm; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002945:Cisplatin / Q000008:administration & dosage; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D015843:Serpins; D002583:Uterine Cervical Neoplasms / Q000097:blood / Q000188:drug therapy / Q000276:immunology*
D000951:Antigens, Neoplasm; D000970:Antineoplastic Agents; D015843:Serpins; C051072:squamous cell carcinoma-related antigen; D002945:Cisplatin; D005472:Fluorouracil