[Comparison of bronchial reactivity to prostaglandin F2 alpha and histamine].
Bronchial reactivity to prostaglandin F2 alpha (PGF2 alpha) and histamine have been examined in 15 asthmatics and 8 healthy youngsters. The degree of reactivity was estimated on the basis of values of PC20 PGF2 alpha and histamine [provocative concentration of PGF2 alpha and histamine in mg/l which lead to the fall in the expiration volume in the first second (FEV1) for 20% of the basal value]. In the group of asthmatics statistically significant correlation was found between PC20 PGF2 alpha and histamine values (r = 0.538, p less than 0.05).
Ninković
M
M
Radojicić
M
M
D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000503:physiopathology*; D001980:Bronchi / Q000187:drug effects* / Q000503:physiopathology; D001985:Bronchial Provocation Tests; D015237:Dinoprost / Q000494:pharmacology*; D006632:Histamine / Q000494:pharmacology*; D006801:Humans; D008297:Male
D006632:Histamine; D015237:Dinoprost
Poredenje reaktivnosti bronha na prostaglandin F2 alfa i histamin.