Intravascular lymphomatosis (malignant angioendotheliomatosis) presenting as pulmonary hypertension.
Intravascular lymphomatosis is a rare lymphoma characterized by proliferation of malignant cells within the lumen of small blood vessels. We describe a case of intravascular lymphomatosis resulting in pulmonary hypertension, hypoxemia, and dyspnea. This lymphoma occasionally responds to combination chemotherapy, suggesting that pulmonary hypertension secondary to intravascular lymphomatosis may be reversible. Intravascular lymphomatosis should be considered in the differential diagnosis of pulmonary hypertension.
Snyder
L S
LS
Department of Medicine, University of Minnesota Medical School, Minneapolis 55455.
Harmon
K R
KR
Estensen
R D
RD
D000368:Aged; D006390:Hemangioendothelioma / Q000150:complications* / Q000473:pathology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology*; D008175:Lung Neoplasms / Q000150:complications* / Q000473:pathology; D008297:Male; D011651:Pulmonary Artery / Q000473:pathology; D011667:Pulmonary Veins / Q000473:pathology