Thrombophlebitis migrans following co-trimoxazole therapy.
We report an unusual and severe vasculitic disorder following co-trimoxazole, given orally for a urinary tract infection. The vasculitis was manifest solely as thrombophlebitis migrans and involving only veins without evidence of polyarteritis nodosa, or underlying malignancy.
Verne-Pignatelli
J
J
Division of Immunological Medicine, Northwick Park Hospital, Harrow, Middlesex, UK.
Spickett
G P
GP
Dalgleish
A G
AG
Denman
A M
AM
D000892:Anti-Infective Agents, Urinary / Q000009:adverse effects*; D004338:Drug Combinations / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D013420:Sulfamethoxazole / Q000009:adverse effects*; D013924:Thrombophlebitis / Q000139:chemically induced*; D014295:Trimethoprim / Q000009:adverse effects*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
D000892:Anti-Infective Agents, Urinary; D004338:Drug Combinations; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim; D013420:Sulfamethoxazole