A comparison between propofol and thiopentone as induction agents in obstetric anaesthesia.
Two comparable series of 21 patients who had elective Caesarean section had general anaesthesia induced by thiopentone sodium 4.53 (SD 0.65) mg/kg or propofol 2.15 (SD 0.26) mg/kg. Maintenance was similar for both groups. Blood pressure was lower in the propofol group during the induction-delivery interval. Umbilical/maternal vein ratios for thiopentone and propofol were 8.5 and 7.2 respectively. Infant wellbeing as judged by Apgar score and cord blood analysis showed little difference between the two induction agents. Factors associated with uterine relaxation and bleeding were similar in the two groups.
Moore
J
J
Department of Anaesthetics, Queen's University of Belfast.
Bill
K M
KM
Flynn
R J
RJ
McKeating
K T
KT
Howard
P J
PJ
D000328:Adult; D000773:Anesthesia, Obstetrical / Q000379:methods*; D000777:Anesthetics / Q000097:blood; D002585:Cesarean Section; D004341:Drug Evaluation; D005260:Female; D005312:Fetal Blood; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D015742:Propofol / Q000097:blood; D011897:Random Allocation; D013874:Thiopental
D000777:Anesthetics; D013874:Thiopental; D015742:Propofol