title: Transient hypopyon with marked anterior chamber fibrin following pars plana vitrectomy and silicone oil injection.
abstract: In a retrospective review of 30 cases of complex retinal detachment, which had been managed by pars plana vitrectomy techniques together with silicone oil injection, we found that two patients developed marked postoperative anterior chamber fibrin and hypopyon. In all 30 cases, the same silicone oil was used: purified and heat-sterilized trimethylsiloxy-terminated, polydimethylsiloxane of 1000-centistoke viscosity. Although the silicone oil itself remained clear and without emulsification, the differential diagnosis of this postoperative inflammation included microbial endophthalmitis. These two cases were treated with frequent topical steroids and antibiotics while we closely monitored the retraction of the anterior chamber fibrin. In both cases, clinical improvement and long-term retinal reattachment with satisfactory visual function were achieved. The use of intense scatter laser endophotocoagulation and the presence of impurities in the silicone oil may have contributed to the excessive postoperative inflammation in these cases.
authors: Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, School of Medicine, FL 33136.
authors: R N
authors: RN
authors: Johnson
authors: H W
authors: HW
authors: Flynn
authors: J M
authors: JM
authors: Parel
authors: L M
authors: LM
authors: Portugal
mesh_terms: D000867:Anterior Chamber / Q000378:metabolism*; D009877:Endophthalmitis / Q000209:etiology; D005337:Fibrin / Q000378:metabolism*; D006801:Humans; D007267:Injections; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D012827:Silicone Oils; D013492:Suppuration / Q000209:etiology*; D013997:Time Factors; D014821:Vitrectomy / Q000379:methods*
chemical_list: D012827:Silicone Oils; D005337:Fibrin