Extensive bone marrow necrosis in cancer.
Extensive bone marrow necrosis is an uncommon finding in patients with cancer. This paper presents the clinical details of two patients in whom this condition was the presenting feature. The diagnostic criteria, pathogenesis and prognosis of this poorly understood problem are then discussed. Although prognosis is usually grave, prompt recognition and proper management of this condition may result in remission of the disease and regeneration of the marrow.
Suri
R
R
Department of Medicine, National University of Singapore.
Tan
Y O
YO
D000328:Adult; D000368:Aged; D001853:Bone Marrow / Q000473:pathology*; D006801:Humans; D008297:Male; D009336:Necrosis; D011379:Prognosis; D013274:Stomach Neoplasms / Q000473:pathology* / Q000556:secondary