title: Resistance to serum bactericidal activity distinguishes Brazilian purpuric fever (BPF) case strains of Haemophilus influenzae biogroup aegyptius (H. aegyptius) from non-BPF strains. Brazilian Purpuric Fever Study Group.
abstract: We studied the ability of normal human serum to lyse H. influenzae biogroup aegyptius (H. aegyptius) isolates recovered from patients with Brazilian purpuric fever (BPF clone) or non-BPF clone strains. BPF clone isolates, although similar to non-BPF clone isolates with regard to the ability to fix C3 to their surfaces, could be distinguished from non-BPF clone strains by their resistance to lysis in vitro following incubation with normal adult human serum.
authors: Department of Pediatrics, New York Hospital-Cornell Medical Center, New York 10021.
authors: M H
authors: MH
authors: Porto
authors: G J
authors: GJ
authors: Noel
authors: P J
authors: PJ
authors: Edelson
mesh_terms: D001770:Blood Bactericidal Activity; D002675:Child, Preschool; D003176:Complement C3 / Q000276:immunology; D003168:Complement Fixation Tests; D003171:Complement Pathway, Classical; D003234:Conjunctivitis, Bacterial / Q000382:microbiology*; D006192:Haemophilus Infections / Q000382:microbiology*; D006193:Haemophilus influenzae / Q000145:classification / Q000276:immunology; D006801:Humans; D011693:Purpura / Q000382:microbiology*; D013045:Species Specificity
chemical_list: D003176:Complement C3