Mammalian sex-chromosome evolution: a conserved homoeologous segment on the X and Y chromosomes in primates.
In a representative sample of primate species, including simians (Catarrhini and Platyrrhini) and prosimians (Lemuriformes and Lorisiformes), high-resolution, early replication banding revealed a homoeologous early replicating segment at the ends of both sex chromosomes. The DXYZ2 element, a repeated sequence specific for the human pseudoautosomal region, is conserved in the genomes of all primate species studies and is specifically localized in the distal early replicating segments of the X and Y chromosomes. Thus, cytogenetic and molecular evidence is presented of a highly conserved sex-chromosomal segment in primates. The pseudoautosomal behavior of this segment is discussed.
Schempp
W
W
Institut für Humangenetik und Anthropologie der Universität Freiburg, FRG.
Weber
B
B
Müller
G
G
D000818:Animals; D001483:Base Sequence; D015139:Blotting, Southern; D004247:DNA; D005260:Female; D008297:Male; D008322:Mammals / Q000235:genetics*; D008938:Mitosis; D009693:Nucleic Acid Hybridization; D011323:Primates / Q000235:genetics*; D011544:Pseudogenes; D012689:Sequence Homology, Nucleic Acid; D014960:X Chromosome; D014998:Y Chromosome
D004247:DNA