Effect of diluting propofol on the incidence of pain on injection and venous sequelae.
The effect of diluting propofol in 5% dextrose on the incidence of i.v. injection pain was studied in 100 adult patients. Severe injection pain occurred in 32% (16 patients) who received undiluted propofol, compared with 10% (five patients) who received dilute propofol. We concluded that the dilution of propofol significantly reduced the incidence of severe pain during injection without increasing postoperative venous sequelae.
Stokes
D N
DN
University Department of Anaesthetics, Queen Elizabeth Hospital, Edgbaston, Birmingham.
Robson
N
N
Hutton
P
P
D000328:Adult; D000771:Anesthesia, Intravenous / Q000009:adverse effects*; D000777:Anesthetics / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D010146:Pain / Q000517:prevention & control*; D010636:Phenols / Q000008:administration & dosage* / Q000009:adverse effects; D011183:Postoperative Complications / Q000209:etiology; D015742:Propofol; D013997:Time Factors; D014652:Vascular Diseases / Q000139:chemically induced*
D000777:Anesthetics; D010636:Phenols; D015742:Propofol