New modified trichothecenes accumulated in solid culture by mutant strains of Fusarium sporotrichioides.
Mutant strains of Fusarium sporotrichioides NRRL 3299 deficient in the ability to synthesize T-2 toxin were examined on solid rice medium. Five novel alicyclic trichothecenes were isolated: 11 alpha-hydroxytrichodiene; tricho-9-ene-2 alpha,3 alpha,11 alpha-triol; tricho-9-ene-2 alpha,3 alpha,8 alpha,11 alpha-tetraol; tricho-9-ene-2 alpha,3 alpha,8 beta,11 alpha-tetraol; and tricho-9-ene-2 alpha,3 alpha,11 alpha,16-tetraol.
McCormick
S P
SP
Northern Regional Research Center, U.S. Department of Agriculture, Peoria, Illinois 61604.
Taylor
S L
SL
Plattner
R D
RD
Beremand
M N
MN
D055598:Chemical Phenomena; D002621:Chemistry; D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D003470:Culture Media; D005670:Fusarium / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009154:Mutation; D012275:Oryza; D012717:Sesquiterpenes / Q000378:metabolism*; D014255:Trichothecenes / Q000302:isolation & purification / Q000378:metabolism*
D003470:Culture Media; D012717:Sesquiterpenes; D014255:Trichothecenes