Vector susceptibility to African trypanosomes.
Susceptibility of tsetse fly to trypanosome depends on two distinct barriers controlling respectively colonization of midgut and, migration to salivary glands. Those barriers are modulated by barely known factors, pertaining to the physiological status of the fly as well as to cytoplasmic and nuclear inheritance. Quantification of colonization (p) and migration (m) rates provides a way to calculate intrinsic vectorial capacity (IVC) as a product IVC = p x m, and to undergo comparative analysis of underlying factors.
Le Ray
D
D
D000818:Animals; D004197:Disease Reservoirs; D007303:Insect Vectors; D014346:Trypanosoma brucei brucei; D014347:Trypanosoma brucei gambiense; D014370:Tsetse Flies / Q000235:genetics / Q000276:immunology / Q000469:parasitology*