[Course and outcome of nephropathies of structural renal dysembryogenesis].
The authors elucidate the role played by structural renal dysembryogenesis in the development, progress and outcome of nephropathies. Based on an analysis of mainly morphobiopsies of the kidneys in 298 patients aged 2.5 to 15 years a high incidence of renal dysembryogenesis is shown as an independent disease entity and as combined with acquired nephropathies. This provides basis for regarding structural deficiency of the kidneys as predisposing factor to the development of immune or microbial inflammation. The long-term (up to 18 years) observation over children with the most frequently occurring variant of renal dysembryogenesis, hypoplastic dysplasia, made it possible to define the main clinico-laboratory characteristics and outcome of the pathology determined by a high rate of the formation of chronic renal failure.
Degtiareva
E M
EM
Ignatova
M S
MS
D000293:Adolescent; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007668:Kidney / Q000196:embryology*; D007674:Kidney Diseases / Q000151:congenital* / Q000235:genetics; D011247:Pregnancy; D011248:Pregnancy Complications
Techenie i iskhod nefropatiĭ pri strukturnom pochechnom dizémbriogeneze.