Irradiation of the hypothalamic-hypophyseal area induces complete regression of mucocutaneous lesions in disseminated histiocytosis X.
We report on a 54-year-old woman with disseminated histiocytosis X who had a complete regression of all mucocutaneous lesions within 1 month from the completion of radiation therapy (4500 cGy) to the hypothalamic-hypophyseal (H-H) area. This response lasted 12 months, after which new cutaneous and bone lesions appeared.
Palmieri
G
G
Istituto di Oncologia, II Facoltà di Medicina Chirurgia, Università degli Studi di Napoli, Italy.
Stefani
S
S
Gridelli
C
C
Conte
A
A
Airoma
G
G
Contegiacomo
A
A
Bianco
A R
AR
D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000532:radiotherapy*; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000528:radiation effects*; D008875:Middle Aged; D012074:Remission Induction; D014845:Vulvar Diseases / Q000532:radiotherapy*