The effects of calcitonin gene-related peptide on the blood flow of the upper respiratory tract and the middle and inner ear.
The effects of intravenously infused CGRP on regional blood flows and vascular resistance in the upper respiratory tract, the middle ear, and the inner ear were studied in cats. CGRP caused a pronounced vasodilation and an increase in blood flow of the respiratory mucosa and structures of the middle ear. The substance did not affect the blood flows of the cochlea and the vestibular organ in the inner ear.
Hillerdal
M
M
Department of Physiology and Medical Biophysics, Uppsala University, Sweden.
Andersson
S E
SE
D000818:Animals; D002116:Calcitonin / Q000378:metabolism; D015740:Calcitonin Gene-Related Peptide; D002415:Cats; D007758:Ear, Inner / Q000098:blood supply*; D004432:Ear, Middle / Q000098:blood supply*; D009479:Neuropeptides / Q000494:pharmacology*; D012039:Regional Blood Flow / Q000187:drug effects; D012137:Respiratory System / Q000098:blood supply*; D014655:Vascular Resistance / Q000187:drug effects; D014665:Vasodilator Agents / Q000494:pharmacology*
D009479:Neuropeptides; D014665:Vasodilator Agents; D002116:Calcitonin; D015740:Calcitonin Gene-Related Peptide