[A preliminary study on determining total serum IgE and specific anti-mite IgE antibody in cigarette manufacturing workers].
Total serum IgE and specific anti-mite IgE antibody (IgEAM) were determined in cigarette manufacturing workers with (but not asthma) or without respiratory symptoms (30 cases in each) 16 patients with bronchial asthma, 8 with asthmatic bronchitis and 6 with other respiratory diseases. The total serum IgE level was significantly higher in symptomatic workers (825.8 +/- 22.3 IU/ml) than that of asymptomatic (162.1 +/- 28.0 IU/ml) (P less than 0.001) and patients with other respiratory diseases (P less than 0.05), but was lower than that of patients with bronchial asthma (3310.3 +/- 26.3 IU/ml) and asthmatic bronchitis (2278.4 +/- 25.5 IU/ml) (P less than 0.001). IgEAM was undetectable in all cases except one with asymptomatic worker and one with asthma. The respiratory symptoms in these workers seemed to be related to type I allergic reaction, possibly due to the chemical components in the cigarettes.
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D000328:Adult; D000818:Animals; D001249:Asthma / Q000209:etiology / Q000276:immunology*; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D008875:Middle Aged; D008925:Mites / Q000276:immunology*; D009784:Occupational Diseases / Q000276:immunology*; D010947:Plants, Toxic; D012907:Smoking / Q000009:adverse effects; D014026:Nicotiana
D007073:Immunoglobulin E