title: Measurement of low-frequency receptor potentials in inner hair cells: a theoretical analysis.
abstract: The measurement of the low-frequency responses of inner hair cells is complicated by the fact that extracellular cochlear microphonic may be larger than the intracellular inner hair cell potential. A subtraction technique is proposed in which the extracellular and intracellular potentials are recorded sequentially and then subtracted to give an estimate of the true membrane potential. A theoretical analysis is presented which predicts that this calculated inner hair cell membrane potential is a more accurate measure of inner hair cell receptor current than the membrane potential measured with respect to a remote indifferent electrode.
authors: Department of Biomedical Engineering, Boston University, Massachusetts 02215.
authors: D C
authors: DC
authors: Mountain
mesh_terms: D000161:Acoustic Stimulation; D000818:Animals; D005072:Evoked Potentials, Auditory; D006198:Hair Cells, Auditory / Q000502:physiology*; D006199:Hair Cells, Auditory, Inner / Q000502:physiology*; D008954:Models, Biological; D009925:Organ of Corti / Q000502:physiology