[Differential diagnosis of osteomalacia and other forms of renal osteodystrophy in terminal renal failure by dynamic scintigraphy with diphosphonate].
During osteomalacia in patients with terminal renal failure, the coefficient of diphosphonate elimination from the blood bed (K1) was less than 0.1 min-1, which was determined by the rise of the concentration of uremic toxins, inhibiting interaction of the radiopharmaceutical with the bone, in the patients' tissues. Dynamic scintigraphy permits one to study the pharmacokinetics of diphosphonate in every patient and thus can be used for differential diagnosis between osteomalacia and other forms of renal osteodystrophy.
Novikov
A I
AI
Ermolenko
A E
AE
Ermakova
I P
IP
Baeva
L B
LB
Levitskiĭ
E R
ER
D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000000981:diagnostic imaging* / Q000209:etiology; D003937:Diagnosis, Differential; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000000981:diagnostic imaging; D010018:Osteomalacia / Q000000981:diagnostic imaging* / Q000209:etiology; D011877:Radionuclide Imaging; D013669:Technetium Tc 99m Medronate
D013669:Technetium Tc 99m Medronate
Differentsial'naia diagnostika osteomaliatsii s drugimiformami pochechnoĭ osteodistrofii pri terminal'noĭ pochechnoĭ nedostatochnosti metodom dinamicheskoĭ stsintigrafii s difosfonatom.