title: Comparative in vitro activities of ofloxacin, difloxacin, ciprofloxacin, and other selected antimicrobial agents against Brucella melitensis.
abstract: The in vitro activities of three quinolones (ofloxacin, difloxacin, and ciprofloxacin) were compared with those of trimethoprim-sulfamethoxazole, streptomycin, tetracycline, and rifampin against 47 Brucella melitensis strains. Ofloxacin was the most active of the test antimicrobial agents. It inhibited 90% of B. melitensis strains at a concentration of 0.02 micrograms/ml.
authors: King Fahad National Guard Hospital, Riyadh, Kingdom of Saudi Arabia.
authors: M Y
authors: MY
authors: Khan
authors: M
authors: M
authors: Dizon
authors: F W
authors: FW
authors: Kiel
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D002002:Brucella / Q000187:drug effects*; D002006:Brucellosis / Q000382:microbiology; D002939:Ciprofloxacin / Q000031:analogs & derivatives / Q000494:pharmacology; D024841:Fluoroquinolones; D006801:Humans; D008826:Microbial Sensitivity Tests; D015242:Ofloxacin / Q000494:pharmacology
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D002939:Ciprofloxacin; C047225:difloxacin; D015242:Ofloxacin