title: Glucose enhancement of performance on memory tests in young and aged humans.
abstract: Recent findings indicate that glucose administration enhances memory processes in rodents. This study examined the effects of glucose on memory in humans. After drinking glucose- or saccharin-flavored beverages, college-aged and elderly humans were tested with modified versions of the Wechsler Memory Scale. Beverages and tests were administered in a counter-balanced, crossover design, enabling within subject comparisons. The major findings were: (1) glucose enhanced memory in elderly and, to a lesser extent, in young subjects; and (2) glucose tolerance in individual subjects predicted memory in elderly, but not in young subjects on both glucose and saccharin test days.
authors: Department of Psychology, University of Virginia, Charlottesville 22903.
authors: J L
authors: JL
authors: Hall
authors: L A
authors: LA
authors: Gonder-Frederick
authors: W W
authors: WW
authors: Chewning
authors: J
authors: J
authors: Silveira
authors: P E
authors: PE
authors: Gold
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D001786:Blood Glucose / Q000378:metabolism*; D005950:Glucose Solution, Hypertonic / Q000008:administration & dosage*; D006801:Humans; D008568:Memory; D011939:Mental Recall / Q000502:physiology*; D008875:Middle Aged; D012153:Retention, Psychology / Q000502:physiology*; D014888:Wechsler Scales
chemical_list: D001786:Blood Glucose; D005950:Glucose Solution, Hypertonic