[A case report of graft-versus-host reaction after aortocoronary bypass--a clinicopathological study].
An immunologically normal 70-year-old male developed fever and disturbance of consciousness after aortocoronary bypass; this was followed by diarrhea, systemic erythroderma and granulocytopenia. He died as a result of sepsis and acute renal failure. The skin biopsy showed basel vacuolar degeneration, epidermal eosinophilic necrosis and invasion of T-lymphocytes. The autopsy showed necrotic small interlobular bile ducts, severely hypoplastic bone marrow and widespread necrosis of lymphoid tissue. Based on these clinicopathological findings, we made a diagnosis of graft-versus host reaction after transfusion.
Souma
T
T
Tsuchida
S
S
Otani
S
S
Kojima
M
M
Tsunoda
R
R
D000368:Aged; D001706:Biopsy; D001026:Coronary Artery Bypass; D006086:Graft vs Host Disease / Q000473:pathology*; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000473:pathology*; D012867:Skin / Q000473:pathology; D065227:Transfusion Reaction