Evaluation of diagnostic usefulness of CEA, hCG and SCC antigens in cervical cancer patients.
Pretreatment serum levels of CEA, hCG and SCC antigens were estimated in 130 patients suffering from 0-III FIGO cervix cancer. The mean serum concentrations and the percentages of samples exceeding the cut-off limits were the highest in advanced disease stages and in highly differentiated forms of cancer. Very high specificity of SCC antigen for uterine cervix cancer was established. The simultaneous estimation of three antigens under study did not give more usable clinical information than the estimation of SCC antigen alone.
Kornafel
J
J
Chair of Oncology, University School of Medicine of Wrocław, Poland.
Wawrzkiewicz
M
M
D000941:Antigens / Q000276:immunology; D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor / Q000032:analysis*; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D006063:Chorionic Gonadotropin / Q000097:blood* / Q000276:immunology; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D015843:Serpins; D002583:Uterine Cervical Neoplasms / Q000032:analysis / Q000175:diagnosis*
D000941:Antigens; D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D006063:Chorionic Gonadotropin; D015843:Serpins; C051072:squamous cell carcinoma-related antigen