[Pre- and postpartum hemostasis in type II Willebrand-Jürgens syndrome].
In a female patient with a von Willebrand's disease type II (ristocetin cofactor less than 20%) shortly before and after birth of a son the factor VIII-related antigen and the ristocetin cofactor showed considerable increases, which some weeks later again decreased to the original values. Despite additional thrombocytopenia only on the 4th day post partum an easily controllable uterine haemorrhage was to be established. The risk of haemorrhage in von Willebrand's disease during pregnancy, birth and puerperium seems to be insignificant; nevertheless on the basis of the heterogeneity of this disease a peripartal coagulation-analytic control is regarded necessary.
Lutze
G
G
Institut für Klinische Chemie und Laboratoriumsdiagnostik, Medizinischen Akademie Magdeburg.
Canzler
E
E
Franke
D
D
Töpfer
G
G
D000328:Adult; D001780:Blood Coagulation Tests; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000235:genetics*; D011644:Puerperal Disorders / Q000235:genetics* / Q000628:therapy; D012307:Risk Factors; D014592:Uterine Hemorrhage / Q000235:genetics* / Q000628:therapy; D014842:von Willebrand Diseases / Q000235:genetics*
Prä- und postpartale Hämostase beim von Willebrand-Jürgens-Syndrom Typ II.