Impaired tooth root development after treatment of a cerebellar astrocytoma: a case report.
A young man, previously treated by surgical resection of a grade III cerebellar astrocytoma in combination with irradiation and chemotherapy, was found to display severe generalized root agenesis. This patient also exhibited secondary hypothyroidism and decreased levels of growth hormone. These factors are discussed in relation to their possible role in impaired root development.
Eckles
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TA
UNMC College of Dentistry, Lincoln.
Kalkwarf
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KL
D000293:Adolescent; D001254:Astrocytoma / Q000532:radiotherapy*; D002528:Cerebellar Neoplasms / Q000532:radiotherapy*; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology; D008297:Male; D009805:Odontogenesis / Q000528:radiation effects; D014092:Tooth Root / Q000002:abnormalities*