Tip-link organization in anomalously-oriented hair cells of the guinea pig cochlea.
Stereocilia are described in a group of guinea pigs with abnormal conformation of the outer hair cell stereociliary bundles. Rows of stereocilia were found which were circular instead of V- or W-shaped, and rotated or even reversed in orientation with respect to normal. The stereocilia have however a normal gradation in heights of the rows of stereocilia, and have tip links running in the direction of gradation in height.
Comis
S D
SD
Department of Physiology, Medical School, University of Birmingham, U.K.
Pickles
J O
JO
Osborne
M P
MP
Pepper
C B
CB
D000818:Animals; D003051:Cochlea / Q000648:ultrastructure*; D006168:Guinea Pigs; D006198:Hair Cells, Auditory / Q000648:ultrastructure*; D008855:Microscopy, Electron, Scanning