[Evaluation of cellular immunity in a selected sample of aged subjects].
The immune system in the aging man is known to show age-related defects; the study of the subpopulations in human blood has yielded conflicting results. This mostly seems to be due to the heterogeneity of the subjects admitted to immunogerontological studies. We investigated a group of aged persons fulfilling the admission criteria described in the "SENIEUR" protocol and strictness criteria dietetics. We found a decrease in the number of T cells, while the number of B cells and, above all, the report of the T4/T8 remained constant. There individuals should be considered as optimally healthy and immunologically uncompromised.
Zito
G A
GA
Callipari
S
S
Gambardella
A
A
Cennamo
G
G
Bencivenga
R
R
Verza
M
M
Agliata
A M
AM
Varricchio
M
M
D000328:Adult; D000367:Age Factors; D000368:Aged; D001402:B-Lymphocytes / Q000145:classification; D006801:Humans; D007111:Immunity, Cellular; D007958:Leukocyte Count; D008875:Middle Aged; D013601:T-Lymphocytes / Q000145:classification
Valutazione dell'immunita' cellulare in un campione "selezionato" di soggetti anziani.