[Significance of immunocytochemical indices of body reactivity of workers engaged in the production of carbonic plastics on the base of formaldehyde-containing and epoxide resins].
Findings of the complex study carried out by means of hematologic, cytochemical and immunologic methods on 130 workers engaged for the 5-year period in carbonic plastic production on the basis of methanol-containing and epoxy resins are presented. Dependence of the trends and intensity of reactivity changes on the character of leading unfavourable occupational factors has been established. Immunotoxicity of carbonic plastic dust and prevalence of sensitization reaction under the impact of industrial chemical allergens (methanol, epichlorohydrine) are mainly demonstrated. The study has indicated immunocytochemical signs of forming skin allergic pathology under cytotoxic effect. Groups of workers have been registered for medical supervision on the basis of an individual analysis of functionally interdependent immunologic and cytochemical indices.
Dueva
L A
LA
Ivanova
L A
LA
Molodkina
N N
NN
Pavlova
T A
TA
Kuznetsova
S A
SA
D001402:B-Lymphocytes / Q000276:immunology; D002617:Chemical Industry; D004853:Epoxy Resins / Q000009:adverse effects*; D005557:Formaldehyde / Q000009:adverse effects*; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007150:Immunohistochemistry; D009784:Occupational Diseases / Q000139:chemically induced* / Q000276:immunology*; D010969:Plastics / Q000009:adverse effects*; D012116:Resins, Plant / Q000009:adverse effects*; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology
D004853:Epoxy Resins; D007136:Immunoglobulins; D010969:Plastics; D012116:Resins, Plant; D005557:Formaldehyde
Znachenie immunotsitokhimicheskikh pokazateleĭ reaktivnosti organizma rabochikh, zaniatykh v proizvodstve ugleplastikov na osnove formal'degidsoderzhashchikh i époksidnykh smol.