title: Pharmacokinetics of miocamycin in patients with liver cirrhosis.
abstract: The pharmacokinetics of miocamycin, a new macrolide antibiotic, was studied in 6 healthy controls and 6 patients with compensated liver cirrhosis. The results indicate that in chronic liver disease the kinetics of the drug is altered. Therefore, a dosage adjustment of miocamycin is recommended when dealing with these patients.
authors: Department of Pharmacology, University of Padua, Italy.
authors: P A
authors: PA
authors: Miglioli
authors: P
authors: P
authors: Pivetta
authors: R
authors: R
authors: Orlando
authors: P
authors: P
authors: Palatini
authors: A
authors: A
authors: Varotto
authors: L
authors: L
authors: Okolicsanyi
mesh_terms: D000284:Administration, Oral; D006207:Half-Life; D006801:Humans; D008103:Liver Cirrhosis / Q000378:metabolism*; D015644:Miocamycin / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*
chemical_list: D015644:Miocamycin