title: [Interstitial irradiation of malignant neoplasms of the female genitalia].
abstract: The paper is concerned with the results of interstitial radiotherapy of 31 patients aged 30 to 76. Of them 18 patients had recurrences or metastases to the vagina, 9 patients--vulvar cancer, 4 patients--vaginal cancer. Interstitial radiotherapy with Co and 252Cf sources was used. A method of successive manual administration of intrastats and ionizing radiation sources was employed. The chief modality was interstitial radiotherapy supplemented with teletherapy or application gamma-beam therapy taking into account the time and doses of previous radiotherapy. Complete tumor regression was observed over time (4-27 mos.) in 23 (74.2%) of 31 patients. Radiation effects were manifested in hyperemia, edema of the mucous membrane and filmy epitheliitis at the site of administration of radioactive sources. Interstitial therapy can be a method of choice for a certain group of patients, especially in case of a limited tumor without infiltration to the adjacent organs.
authors: V L
authors: VL
authors: Shpikalov
authors: V B
authors: VB
authors: Atkochius
mesh_terms: D000328:Adult; D000368:Aged; D001918:Brachytherapy; D002142:Californium / Q000627:therapeutic use; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D005260:Female; D005833:Genital Neoplasms, Female / Q000532:radiotherapy*; D006801:Humans; D008875:Middle Aged; D011878:Radiotherapy / Q000009:adverse effects; D014625:Vaginal Neoplasms / Q000532:radiotherapy / Q000556:secondary; D014846:Vulvar Neoplasms / Q000532:radiotherapy
chemical_list: D003037:Cobalt Radioisotopes; D002142:Californium
vernacular_title: Vnutritkanevoe obluchenie zlokachestvennykh novoobrazovaniĭ zhenskoĭ polovoĭ sfery.