title: [Changes of macrophage function after graded physical loading].
abstract: Intensive physical loading (swimming for 3.5 hours with a load amounting to 4% of body weight for rats and for 1 hour without a load for mice) reduced 5-6-fold the clearing function of the mononuclear phagocyte system of untrained animals. The absorption function of Kupffer's cells diminished 2-fold, whereas clearance through macrophages of the lung interstitium was activated. Kupffer's cells of trained animals (daily swimming for 1 hour for 10 days) acquired tolerance to loading. Preliminary administration of zymosan (3-14 days before intensive physical loading) increased the animals' resistance to stress 2-3-fold.
authors: D N
authors: DN
authors: Maianskiĭ
authors: N P
authors: NP
authors: Voronina
mesh_terms: D000818:Animals; D008264:Macrophages / Q000502:physiology*; D051379:Mice; D008808:Mice, Inbred CBA; D005082:Physical Exertion; D051381:Rats; D011919:Rats, Inbred Strains
vernacular_title: Izmenenie funktsiĭ makrofagov posle dozirovannoĭ fizicheskoĭ nagruzki.