title: Pulmonary functional impairment from years of arc welding.
abstract: OBJECTIVE
  The adverse effects of arc welding on pulmonary function have been previously documented. However, in many of these studies, the effects of welding exposure and smoking were not separated. Also, some studies did not adjust for or ignored the effects of asbestosis on pulmonary function. We assessed the long-term effects of welding on pulmonary function in welders who had no evidence of asbestosis on chest radiographs, and adjusted each individual value for height, age, and years of cigarette smoking.
  
  
  METHODS
  The study consisted of 226 male construction welders who had never worked in shipyards. Forced vital capacity (FVC) and flows were measured by spirometry, chest radiographs were obtained and examined for evidence of asbestosis using International Labor Office (ILO) criteria, and thoracic gas volume (TGV) was determined by planimetry. The subjects were also administered an occupational and respiratory questionnaire. Data on workers with asbestosis (ILO profusion 1/0 or greater) and pleural abnormalities were excluded. The mean age for the 226 subjects without asbestosis was 45 years, mean height was 175.7 cm, and mean duration of welding was 21.3 years. Pulmonary function measurements are presented as mean percentage of predicted (pop) and adjusted for height, age, and years of smoking.
  
  
  RESULTS
  In 151 current cigarette smokers, mean midflows and terminal flows were decreased, FEF25-75 to 93.2 pop and FEF75-85 to 91.2 pop, but FVC, forced expiratory volume in one second (FEV1) and TGV were normal. The 43 nonsmokers also had reductions in flows but normal FVC and TGV. Flows in both groups were significantly (p less than 0.05) below those of the referent group. The regression coefficient was -0.0031 for years of welding and FVC pop, -0.0035 for FEV1 pop, and -0.0080 for midflow pop (FEF25-75) (all significant at p less than 0.05), but the coefficient for FEF75-85 pop was not significant. As calculated from regression equations, 40 years of welding would reduce FVC to 95.2 pop, FEV1 to 92.2 pop, midflow to 79.2 pop, and FEF75-85 to 81.7 pop.
  
  
  CONCLUSIONS
  Long-term exposure to welding gases and fumes reduced flows in small airways of welders without asbestosis.
authors: University of Southern California, School of Medicine, Environmental Sciences Laboratory, Los Angeles.
authors: K H
authors: KH
authors: Kilburn
authors: R H
authors: RH
authors: Warshaw
mesh_terms: D000328:Adult; D001991:Bronchitis / Q000453:epidemiology / Q000209:etiology; D003430:Cross-Sectional Studies; D005541:Forced Expiratory Volume; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000453:epidemiology* / Q000503:physiopathology; D008297:Male; D008824:Michigan; D008875:Middle Aged; D009784:Occupational Diseases / Q000453:epidemiology* / Q000503:physiopathology; D012044:Regression Analysis; D012907:Smoking / Q000009:adverse effects; D014797:Vital Capacity; D014896:Welding