The effects of a concurrent infection of Trichostrongylus colubriformis and Ostertagia circumcincta on calcium, phosphorus and magnesium transactions along the digestive tract of lambs.
Twelve lambs, paired on the basis of live weight, were cannulated in the abomasum, proximal jejunum and terminal ileum. Six were infected with 3000 T. colubriformis and 3000 O. circumcincta larvae per day for 18 weeks. The other six lambs were pair-fed to the infected lambs. All animals were offered fresh ryegrass and white clover pasture, cut daily. Dry matter intake, live weight and plasma Ca, P and Mg concentrations were measured throughout the experiment. During weeks 7 and 17 post-infection, digesta flow along the gastrointestinal tract of infected and control animals was measured. Parasitism depressed dry matter intake by 60 per cent and was associated with a reduction in retention of Ca, P and Mg in both infected and control animals. During weeks 7 and 17, parasitism increased the flow of Ca past the proximal jejunum and, during week 17, the flow of P past the terminal ileum. Increased endogenous Ca and P losses, together with a net reduction in absorption of Ca and P, were associated with depressed plasma Ca and P concentrations. These findings, together with evidence of reduced addition of P to anterior regions of the tract, indicate induced Ca and P deficiency. There was evidence for compensatory absorption of Ca and P in the large intestine and distal small intestine, respectively. Magnesium metabolism was apparently not affected by parasitism.
Brown
M D
MD
Animal and Veterinary Sciences Group, Lincoln College, Canterbury, New Zealand.
Poppi
D P
DP
Sykes
A R
AR
D000818:Animals; D002118:Calcium / Q000378:metabolism* / Q000493:pharmacokinetics; D004064:Digestive System / Q000378:metabolism / Q000469:parasitology*; D008274:Magnesium / Q000378:metabolism* / Q000493:pharmacokinetics; D010028:Ostertagia / Q000302:isolation & purification; D010029:Ostertagiasis / Q000150:complications / Q000378:metabolism / Q000662:veterinary*; D010758:Phosphorus / Q000378:metabolism* / Q000493:pharmacokinetics; D012756:Sheep / Q000378:metabolism / Q000469:parasitology*; D012757:Sheep Diseases / Q000378:metabolism* / Q000469:parasitology; D014252:Trichostrongyloidiasis / Q000662:veterinary*; D014253:Trichostrongylosis / Q000150:complications / Q000378:metabolism / Q000662:veterinary*; D014254:Trichostrongylus / Q000302:isolation & purification
D010758:Phosphorus; D008274:Magnesium; D002118:Calcium