Fat/water quantitation and differential relaxation time measurement using chemical shift imaging technique.
The use of chemical shift imaging for fat and water quantitation and differential measurement of relaxation times for the fat and water component is demonstrated using a hybrid technique. The efficacy of the imaging technique for fat and water quantitation has been tested by comparing the results of imaging to the results of volumetric measurements in phantoms with oil and water homogeneously mixed, fat extraction in ground meat of different grades, and biopsy in preliminary clinical studies. Good correlation is found between the fat and water content measured by imaging and that measured by other means except for the inability to differentiate unsaturated fat protons from water protons. Longitudinal (T1) and transverse (T2) relaxation times for water and fat are also shown to be measurable independently when fat and water signal are suppressed accordingly. The independently measured relaxation times correspond closely to those of the pure samples except that unsaturated protons give decreased water relaxation estimates.
Poon
C S
CS
Department of Medical Biophysics, University of Toronto and Ontario, Ontario, Canada.
Szumowski
J
J
Plewes
D B
DB
Ashby
P
P
Henkelman
R M
RM
D001834:Body Water / Q000032:analysis*; D008055:Lipids / Q000032:analysis*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D013997:Time Factors
D008055:Lipids