title: Conservative management of anal and rectal cancer. The role of radiation therapy.
abstract: The role of irradiation in the management of anal and rectal cancer has changed during the past ten years. In small epidermoid carcinomas of the anal canal (T1 T2) irradiation is in most departments considered the primary treatment, giving a 5-year survival rate of between 60 and 80% with good sphincter preservation. Even in larger tumors, irradiation can still offer some chance of cure without colostomy. Surgery remains the basic treatment of rectal cancer but irradiation is used in association with surgery in many cases. Radiotherapy is of value in the conservative management of cancer of the rectum in three situations; In small polypoid cancers contact x-ray therapy can give local control in about 90%. In cancers of the middle rectum, preoperative external irradiation may increase the chances of restorative surgery and reduce the risk of local relapse. In inoperable patients, external radiotherapy and/or intracavitary irradiation may cure some patients with infiltrating tumors (T2 T3) without colostomy.
authors: Department of Radiotherapy, Centre Hospitalier Lyon Sud, Pierre-Benite, France.
authors: J P
authors: JP
authors: Gerard
authors: P
authors: P
authors: Romestaing
authors: X
authors: X
authors: Montbarbon
mesh_terms: D001005:Anus Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D006801:Humans; D007417:Intestinal Polyps / Q000532:radiotherapy; D012004:Rectal Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D015996:Survival Rate