[Soluble interleukin-2 receptor levels in patients with pulmonary tuberculosis].
Utilizing an enzyme-linked immunosorbent assay, we detected markedly elevated serum levels of soluble interleukin-2 (IL-2) receptors in patients with untreated pulmonary tuberculosis. In these patients, we also found that serum levels of soluble IL-2 receptors were closely correlated with serum adenosine deaminase levels (r = 0.869, p less than 0.001). Therefore, serum soluble IL-2 receptors appear to reflect the existence of active cell-mediated immunity in pulmonary tuberculosis and may prove to be a useful immunological marker for pulmonary tuberculosis.
Ito
M
M
Kojiro
N
N
Moriwaki
Y
Y
Nishiki
M
M
Shirasaka
T
T
Ishihara
H
H
Aitani
M
M
Nakatsuji
Y
Y
Hirose
T
T
Okada
M
M
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D008297:Male; D008875:Middle Aged; D015375:Receptors, Interleukin-2 / Q000032:analysis*; D012995:Solubility; D014397:Tuberculosis, Pulmonary / Q000276:immunology*
D015375:Receptors, Interleukin-2