Threshold tracking for assessment of long-term adaptation and sensitization in pain perception.
To assess temporal variations in the perception of "phasic" heat pain stimuli a psychophysical tracking procedure was developed that enables repeated assessment of the pain threshold at short intervals. This "double-tracking" procedure produces two tracking curves simultaneously, one that approaches the pain threshold gradually from above, the other from below. The threshold for phasic heat pain was measured in 80 tracking trials with stimuli at temperatures near the pain threshold. Concurrently, the threshold for "tonic" heat pain was determined after every 20 tracking trials with a stimulus adjustment procedure. Eleven healthy subjects (age: 26.4 yr. +/- 6.0) participated in 2 sessions each. Phasic stimulation near the pain threshold did not produce any trends in either of the two threshold measures. Hence there was no long-term adaptation or sensitization. However, there were random variations (random walks) in the tracking curves, which we interpret as resulting from a stochastic relationship between stimulus and sensation. In agreement with other reports, discrimination seemed to be better at painful than at nonpainful temperatures.
Lautenbacher
S
S
Max Planck Institute for Psychiatry Clinical Department, Munich, Federal Republic of Germany.
Galfe
G
G
Hölzl
R
R
Strian
F
F
D000222:Adaptation, Physiological; D000328:Adult; D005246:Feedback; D005260:Female; D006358:Hot Temperature; D006801:Humans; D008297:Male; D010146:Pain / Q000503:physiopathology; D010147:Pain Measurement / Q000379:methods*; D012684:Sensory Thresholds; D013697:Thermosensing / Q000502:physiology