The minimum inhibitory concentrations of various bismuth salts against Campylobacter pylori.
The minimum inhibitory concentrations of five bismuth salts (bismuth subcitrate, bismuth subgallate, bismuth subnitrate, bismuth subsalicylate and tripotassium dicitrato bismuthate, a water soluble compound of bismuth subcitrate) were assayed against 48 strains of Campylobacter pylori employing the agar dilution method. Tripotassium dicitrato bismuthate was most effective (MIC50 8 mg/l), the other bismuth salts exhibited somewhat lower inhibitory activities. It is concluded that bismuth salts are suitable agents for inhibiting growth of Campylobacter pylori.
Vogt
K
K
Institut für Medizinische Mikrobiologie der Freien Universität Berlin.
Warrelmann
M
M
Hahn
H
H
D000863:Antacids / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000897:Anti-Ulcer Agents / Q000494:pharmacology; D001729:Bismuth / Q000494:pharmacology*; D002167:Campylobacter / Q000187:drug effects* / Q000254:growth & development; D005707:Gallic Acid / Q000494:pharmacology / Q000031:analogs & derivatives; D006801:Humans; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000494:pharmacology; D012459:Salicylates / Q000494:pharmacology
D000863:Antacids; D000900:Anti-Bacterial Agents; D000897:Anti-Ulcer Agents; D009942:Organometallic Compounds; D012459:Salicylates; C015715:bismuth subsalicylate; D005707:Gallic Acid; C010804:bismuth subnitrate; C002791:bismuth tripotassium dicitrate; D001729:Bismuth; C002170:bismuth subgallate