title: A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched.
abstract: The patterning of cells in insect segments requires the exchange of information between cells, which in Drosophila depends on the activity of members of the segment-polarity class of genes. Here we report the molecular characterization of one such gene, patched. We find that patched encodes a large protein with several possible membrane-spanning domains and is expressed in a complex pattern during embryogenesis.
authors: ICRF Developmental Biology Unit, Department of Zoology, Oxford, UK.
authors: Y
authors: Y
authors: Nakano
authors: I
authors: I
authors: Guerrero
authors: A
authors: A
authors: Hidalgo
authors: A
authors: A
authors: Taylor
authors: J R
authors: JR
authors: Whittle
authors: P W
authors: PW
authors: Ingham
mesh_terms: D000483:Alleles; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics; D004330:Drosophila / Q000196:embryology / Q000235:genetics*; D004625:Embryo, Nonmammalian / Q000502:physiology; D005796:Genes; D008565:Membrane Proteins / Q000235:genetics*; D008969:Molecular Sequence Data; D011487:Protein Conformation; D015183:Restriction Mapping
chemical_list: D008565:Membrane Proteins; D004247:DNA