Amino acids bracketing the predicted transmembrane domains of membrane proteins.
The cell membrane is a complex mixture of several classes of biomolecules but amino acids and lipids are the main constituents. For this reason we are establishing a data base of transmembrane proteins with the intent of using the data base to identify interfacial peptide sequences useful for studying protein-lipid interactions at membrane interfaces. Our present intention is to characterize transmembrane peptides and amino acids found near the membrane interface. A data base containing only signal peptides is available (G. von Heijne, Prot. Seq. Data Anal. 1:41-42, 1987).
Pidgeon
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C
Department of Industrial and Physical Pharmacy, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, Indiana 47907.
Williard
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RL
Schroeder
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SC
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis*; D002462:Cell Membrane / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D008563:Membrane Lipids / Q000032:analysis; D008565:Membrane Proteins / Q000032:analysis*; D008956:Models, Chemical; D008969:Molecular Sequence Data; D010455:Peptides / Q000032:analysis; D011487:Protein Conformation
D000596:Amino Acids; D008563:Membrane Lipids; D008565:Membrane Proteins; D010455:Peptides