title: Quantitative genetic analysis of longitudinal trends in adoption designs with application to IQ in the Colorado Adoption Project.
abstract: A factor model is presented that provides for either multivariate or developmental specification of longitudinal genetic and environmental effects in the presence of assortative mating and cultural transmission. Delta path methods are employed for the treatment of assortative mating and selective placement effects. The proportions of genetic and environmental variance and covariance attributable to assortative mating and cultural transmission are modeled explicitly. The model was applied to cognitive ability data on 493 families in the Colorado Adoption Project by means of maximum-likelihood pedigree analysis. A test of the assumption of multivariate normality of error provided an additional model criterion beyond the log-likelihood ratio statistic. No significant effects were found for cultural transmission, genetic-environmental covariance, or selective placement. The results suggest that the phenotypic stability of IQ during early childhood is largely, if not entirely, genetic in origin and that these longitudinal genetic effects can be represented most parsimoniously in the form of developmental transmission.
authors: K
authors: K
authors: Phillips
authors: D W
authors: DW
authors: Fulker
mesh_terms: D000300:Adoption; D002648:Child; D003120:Colorado; D006801:Humans; D007360:Intelligence; D008137:Longitudinal Studies; D008957:Models, Genetic; D015233:Models, Statistical; D010641:Phenotype; D012931:Social Environment