[Propafenone per os in ventricular arrhythmia].
Twenty-one patients presenting ventricular rhythm disorders and admitted to the Intensive Care Unit were treated with oral propafenone at the dosage of 450 to 900 mg/hours. The results of treatment were excellent in 13 cases, average in 2 cases, and nil in 4 cases. Worsening of arrhythmia was observed in 2 cases. Generally the drug was well tolerated, with treatment requiring to be discontinued in 1 case due to gastrointestinal upset and in another case due to broadening of the QRS complex. This study confirms that oral propafenone is well tolerated in ventricular arrhythmias regardless of their etiology.
Colas
A
A
Service de soins intensifs, Centre hospitalier de Chalon-sur-Saône.
Maarek-Charbit
M
M
D000284:Administration, Oral; D000368:Aged; D000369:Aged, 80 and over; D001145:Arrhythmias, Cardiac / Q000188:drug therapy*; D003422:Critical Care; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011405:Propafenone / Q000008:administration & dosage / Q000627:therapeutic use*
D011405:Propafenone
Propafénone per os dans les troubles du rythme ventriculaire.