title: Isthmo-optic connections in congenitally monophthalmic chicks.
abstract: By means of retrograde transport of horseradish peroxidase, isthmo-optic projections were investigated in 1 to 9-day-old posthatching chickens. Some of the specimens were congenitally anophthalmic, others were monophthalmic. In contrast to a recent study, we did not detect significant differences in the one-eyed chicks. In particular, we find no indication for a retarded elimination of ectopic and aberrantly projecting isthmo-optic neurons during ontogeny. We tentatively suggest that more than one mechanism leading to monophthalmic deformities may exist.
authors: Department of Anatomy, School of Medicine, University of Gottingen, Federal Republic of Germany.
authors: C R
authors: CR
authors: Malz
authors: S
authors: S
authors: Pritz
authors: D L
authors: DL
authors: Meyer
mesh_terms: D000818:Animals; D001921:Brain / Q000033:anatomy & histology* / Q000502:physiology; D002645:Chickens; D004525:Efferent Pathways / Q000033:anatomy & histology / Q000502:physiology; D007839:Functional Laterality / Q000502:physiology*; D006735:Horseradish Peroxidase; D009473:Neuronal Plasticity; D012160:Retina / Q000166:cytology*; D014795:Visual Pathways / Q000033:anatomy & histology* / Q000502:physiology
chemical_list: D006735:Horseradish Peroxidase