title: Multiphoton, time-of-flight three-dimensional radionuclide imaging.
abstract: A method for applying time-of-flight (TOF) information to the three-dimensional (3-D) localization of multiple-photon-emitting radionuclides is presented. The same principle used for TOF imaging of positron annihilation photons is suggested for use with nuclides that emit two photons (gamma or x rays) in near coincidence. Two photons originating from the same decay event are detected. The locations at which they are detected become the foci of a hyperbola described by the difference in their path length. If one detector is collimated a line is established by the photon it detects, which intersects the hyperbola at the origin of the event. Should TOF imaging become a reality, this technique would extend its usefulness to nuclides that do not emit positrons.
authors: Department of Radiology, Norwalk Hospital, Connecticut 06856.
authors: M D
authors: MD
authors: Powell
mesh_terms: D006283:Health Physics; D006801:Humans; D011827:Radiation; D011877:Radionuclide Imaging / Q000379:methods*; D012542:Scattering, Radiation; D013997:Time Factors; D015899:Tomography, Emission-Computed, Single-Photon