title: [Assessment of myocardial necrosis by 111In-antimyosin F ab scintigraphy].
abstract: 111In-antimyosin F ab (AM) myocardial scintigraphy was carried out in (A) 13 patients with acute myocardial infarction (9.9 +/- 2.2 days from the onset) and (B) 9 with myocarditis and/or dilated cardiomyopathy. Forty eight hours after injection of AM, the patients were injected with 74 MBq (2 mCi) of thallium-201 (TL). The two sets of Planar and SPECT image were obtained simultaneously using dual energy window sets. In group A, positive focal AM uptake was demonstrated in 12 (92%) patients. Higher AM uptake was observed in patients who had PTCR/PTCA. By combination with TL, it is useful to detect inferior infarction and to differentiate old from acute infarction. Dual SPECT images gave precise information about the infarcted area. In group B, positive diffuse AM uptake was demonstrated in 7 (77%) patients. In conclusion, AM myocardial scintigraphy was proven to be useful for the assessment of acute necrosis after myocardial infarction but also on-going necrosis of myocarditis and/or myopathy.
authors: T
authors: T
authors: Nishimura
authors: I
authors: I
authors: Mitani
authors: H
authors: H
authors: Oka
authors: K
authors: K
authors: Hayashida
authors: T
authors: T
authors: Uehara
authors: S
authors: S
authors: Kumita
authors: H
authors: H
authors: Okizuka
authors: H
authors: H
authors: Yamagami
authors: M
authors: M
authors: Hayashi
authors: K
authors: K
authors: Haze
mesh_terms: D000328:Adult; D000368:Aged; D000911:Antibodies, Monoclonal; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D007205:Indium Radioisotopes; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000473:pathology; D009206:Myocardium / Q000473:pathology*; D009218:Myosins / Q000276:immunology*; D009336:Necrosis; D013794:Thallium Radioisotopes; D014055:Tomography, Emission-Computed
chemical_list: D000911:Antibodies, Monoclonal; D007205:Indium Radioisotopes; D013794:Thallium Radioisotopes; D009218:Myosins