title: Sialyltransferase activity in plasma cells of multiple myeloma.
abstract: A marked elevation of sialyltransferase activity (STA) was observed in a solid tumor of plasma cells, which had been removed from a patient with multiple myeloma (MM), as compared to normal lymphatic tissues. STA was also determined in mononuclear bone marrow cells of 10 patients with MM and found to be 12 times higher than that of bone marrow mononuclear cells from 5 patients with non-malignant disorders (with less than 1% plasma cells in the bone marrow aspirate). A significant correlation was found between STA and the number of plasma cells in the bone marrow aspirate.
authors: Hematology Clinic, Sackler School of Medicine, Tel-Aviv University, Israel.
authors: A M
authors: AM
authors: Cohen
authors: D
authors: D
authors: Allalouf
authors: M
authors: M
authors: Djaldetti
authors: K
authors: K
authors: Weigl
authors: N
authors: N
authors: Lehrer
authors: H
authors: H
authors: Levinsky
mesh_terms: D001853:Bone Marrow / Q000201:enzymology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000201:enzymology*; D010950:Plasma Cells / Q000201:enzymology*; D012799:Sialyltransferases / Q000032:analysis*
chemical_list: D012799:Sialyltransferases