title: Chromosomal analyses of human lymphocytes exposed in vitro to caprolactam.
abstract: Caprolactam was tested for the induction of chromosomal aberrations in cultured human lymphocytes from one male donor and one female donor. At 7.5 mg/ml, caprolactam-treated cells from the male showed a small but significant increase in the frequency of aberrations. No effect was observed in cells from the female if gaps are excluded.
authors: Paterson Institute for Cancer Research, Christie Hospital and Holt Radium Institute, Withington, Manchester, Great Britain.
authors: E
authors: E
authors: Kristiansen
authors: D
authors: D
authors: Scott
mesh_terms: D000328:Adult; D001381:Azepines / Q000633:toxicity*; D002209:Caprolactam / Q000633:toxicity*; D002470:Cell Survival / Q000187:drug effects; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000187:drug effects* / Q000648:ultrastructure; D008297:Male; D008677:Metaphase / Q000187:drug effects; D009153:Mutagens
chemical_list: D001381:Azepines; D009153:Mutagens; D002209:Caprolactam