title: Successive unfolding of two different collagen vascular diseases in the same patient.
abstract: Genetic factors may be important in the development of autoimmune disease. We describe the development of fulminant systemic lupus erythematosus in a patient 5 years after recovery from polymyositis. The successive unfolding of different autoimmune diseases in the same individual is suggestive of sequential gene activation.
authors: University of Toronto Rheumatic Disease Unit, Women's College Hospital, ON, Canada.
authors: E
authors: E
authors: Gertner
authors: R
authors: R
authors: Goodman
authors: D D
authors: DD
authors: Gladman
mesh_terms: D000974:Antibodies, Antinuclear / Q000032:analysis; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000276:immunology; D008875:Middle Aged; D009220:Myositis / Q000150:complications* / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D000974:Antibodies, Antinuclear; D011241:Prednisone