Single dose prophylactic antibiotics in caesarean sections.
A prospective, double-blind randomized trial was carried out at the Department of Obstetrics and Gynaecology, the Chinese University of Hong Kong, involving 4 groups of patients receiving a single intravenous dose of placebo, ampicillin, ampicillin and metronidazole, and ampicillin and sulbactam before operation. No difference in postoperative morbidity was present between the 4 groups of patients.
Chan
A C
AC
Department of Obstetrics and Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital.
Leung
A K
AK
Chin
R K
RK
Chang
A M
AM
D000328:Adult; D000667:Ampicillin / Q000008:administration & dosage / Q000627:therapeutic use*; D002585:Cesarean Section / Q000009:adverse effects*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008423:Maternal Age; D008795:Metronidazole / Q000008:administration & dosage / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000517:prevention & control*; D011247:Pregnancy; D018566:Pregnancy, High-Risk; D011645:Puerperal Infection / Q000517:prevention & control*; D011897:Random Allocation; D013407:Sulbactam / Q000008:administration & dosage / Q000627:therapeutic use*
D008795:Metronidazole; D000667:Ampicillin; D013407:Sulbactam