[Polysorbates for hemoperfusion. The effect of polysorbate surface modification on morphology, coagulation, fibrinolysis, and kallikrein formation].
In the work the influence of surface sulfonated polymer sorbents with styrene-divinylbenzene (Vinylsorb SS) modified by amino acids upon the morphological picture of blood and proteins of the coagulation system was tested. Those sorbents do not exert a remarkable influence upon erythrocytes and coagulation proteins but they adsorb blood platelets, leucocytes and they activate prekallikrein system. Vinylsorb SS has the best influence because it adsorbs few platelets and activates prekallikrein system to the least extent.
Kotschy
M
M
Katedra i Zakład Patofizjologii Akademii Medycznej w Bydgoszczy.
Jurkowski
P
P
Zekanowska
E
E
D000327:Adsorption; D001672:Biocompatible Materials; D001777:Blood Coagulation / Q000187:drug effects; D005342:Fibrinolysis / Q000187:drug effects; D006464:Hemoperfusion / Q000295:instrumentation*; D011136:Polysorbates / Q000493:pharmacokinetics / Q000494:pharmacology*; D011288:Prekallikrein / Q000096:biosynthesis*
D001672:Biocompatible Materials; D011136:Polysorbates; D011288:Prekallikrein
Sorbenty polimerowe do hemoperfuzji. 2. Wpływ modyfikacji powierzchniowej sorbentów polimerowych na morfologie, krzepliwość, fibrynolize i kalikreinogeneze.