Polymyositis/dermatomyositis associated with dermatitis herpetiformis.
We describe 2 patients with dermatitis herpetiformis who developed polymyositis/dermatomyositis. On HLA typing, both patients were found to be HLA-B8, DR3 positive. The concurrence of these two relatively rare diseases, both associated with immunologic abnormalities, further supports the role of autoimmunity in their pathogenesis and indicates a possible common genetic basis. It also suggests that myositis may be more common in patients with dermatitis herpetiformis than in the general population.
Kalovidouris
A E
AE
Rheumatology Division, Indiana University School of Medicine, Indianapolis.
Miller
F W
FW
Lawley
T J
TJ
D000328:Adult; D001327:Autoimmune Diseases / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D003874:Dermatitis Herpetiformis / Q000150:complications* / Q000276:immunology / Q000473:pathology; D003882:Dermatomyositis / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D015235:HLA-B Antigens / Q000032:analysis; D015795:HLA-B8 Antigen; D006684:HLA-DR Antigens / Q000032:analysis; D015803:HLA-DR3 Antigen; D006801:Humans; D008297:Male; D009220:Myositis / Q000209:etiology* / Q000276:immunology / Q000473:pathology
D015235:HLA-B Antigens; D015795:HLA-B8 Antigen; D006684:HLA-DR Antigens; D015803:HLA-DR3 Antigen