[Avoidance of allergens as a therapeutic starting point in childhood bronchial asthma].
Allergen avoidance is accepted to be a valuable therapeutic measure, when acute bronchospasms occur in immediate response to antigen challenge. However, many children with asthma (and their parents) will attribute their attacks to nonspecific triggers rather than to allergen exposure. So, if an evident correlation cannot be established, allergen avoidance seems to be of questionable value. The immunological mechanism by which allergens contribute to asthma are not restricted to immediate type reactions. But they are likely to produce and maintain an inflammation of the airways, which may be an important cause to the seemingly nonspecific bronchial hyperreactivity. Reduction of allergen load as well as the avoidance of non specific trigger factors is likely to reduce the nonspecific bronchial hyperreactivity as well as acute attacks. Thus, together with a symptomatic treatment a significant improvement may be achieved.
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D000485:Allergens; D001249:Asthma / Q000276:immunology / Q000517:prevention & control*; D002648:Child; D002675:Child, Preschool; D004781:Environmental Exposure; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology; D007223:Infant
D000485:Allergens
Allergenkarenz als therapeutischer Ansatzpunkt beim kindlichen Asthma bronchiale.