Inertance of the respiratory system in ponies.
The purpose of the present work was to measure the pulmonary inertance (IL) in ponies and to analyze its potential influence on the mechanics of breathing and on their aptitude to increase ventilation during exercise. Five healthy ponies 2.4-4 yr old [mean wt 255 +/- 15 (SE) kg] were used. On the one hand, inertance of the respiratory system (Irs) was computed from the value of the resonant frequency (fr) measured by the forced oscillation technique. On the other hand, respiratory airflow, tidal volume (VT), and transpulmonary pressure (PL) changes were recorded while the ponies were performing a light treadmill exercise, and IL was calculated as the ratio of the associated differences in inertial pressure (delta Pin) to volume acceleration (delta V). Respiratory airflow and VT were measured with a Fleisch pneumotachograph (no. 5) and PL with an intraesophageal balloon catheter. First, the protocol was carried out with the ponies breathing air and He-O2, second, while the ponies breathed through two additional tubes (100 cm long, 3 cm ID), then one, and finally none, fixed on the Fleisch pneumotachograph. Finally, the contribution of the extra- vs. the intrathoracic airways to IL was estimated by measuring the lateral midtracheal pressure recorded simultaneously with the aforementioned parameters. The values of Irs calculated with fr and of IL calculated on the basis of the delta Pin-delta V ratio were 29.8 +/- 0.4 and 19.8 +/- 1.0.10(-4) kPa.l-1.s-2, respectively. During He-O2 breathing IL decreased about three times; this result was similar to the predicted decrease based on gas density only.(ABSTRACT TRUNCATED AT 250 WORDS)
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Laboratory for Cardio-Pulmonary Functional Investigation, Faculty of Veterinary Medicine, University of Liege, Brussels, Belgium.
Lekeux
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Gustin
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Desmecht
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Amory
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Paiva
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D000818:Animals; D006736:Horses / Q000502:physiology*; D010101:Oxygen Consumption; D010805:Physical Conditioning, Animal; D011312:Pressure; D011669:Pulmonary Wedge Pressure; D012119:Respiration; D012143:Respiratory Physiological Phenomena