title: Woven carbon-fibre patch versus Dacron mesh in the repair of experimental defects in the lumbar fascia of rabbits.
abstract: Defects were created in the lumbar fascia of adult New Zealand white rabbits and repaired with either woven carbon-fibre or Dacron mesh. The histological and mechanical properties of the two materials were compared at intervals up to 12 wk post-operatively. Microscopy showed an abundant orderly deposition of collagen highly vascularized with a minimal inflammatory response on the carbon fibre, whereas the Dacron mesh induced the formation of a flimsy collagenous capsule, with a marked inflammatory response. Mechanical testing showed a significant increase in the strength of the carbon-fibre patch after 2 wk (P = .001), the patch becoming much stronger than the Dacron mesh (P = .002) 5 to 12 wk after implantation.
authors: Department of Surgery, Dryburn Hospital Durham, UK.
authors: R
authors: R
authors: Ward
authors: R J
authors: RJ
authors: Minns
mesh_terms: D000818:Animals; D002244:Carbon; D003094:Collagen / Q000096:biosynthesis / Q000502:physiology; D005205:Fascia / Q000648:ultrastructure; D000071938:Fasciotomy; D008297:Male; D010795:Phthalic Acids; D011092:Polyethylene Glycols; D011093:Polyethylene Terephthalates; D019736:Prostheses and Implants; D011817:Rabbits; D013526:Surgical Mesh; D013718:Tensile Strength
chemical_list: D010795:Phthalic Acids; D011093:Polyethylene Terephthalates; C025539:Lavsan; D011092:Polyethylene Glycols; D002244:Carbon; D003094:Collagen