title: Is there influence of smoking on the mutagenicity of follicular fluid?
abstract: The mutagenicity of follicular fluid was examined in 24 patients, 12 smoking and 12 nonsmoking, who were treated in an in vitro fertilization program. The Salmonella microsome assay was used. It was found that the mutagenicity of follicular fluid was not influenced by the number of cigarettes smoked. Urine samples of smoking in vitro fertilization (IVF) patients however showed a dose-dependent elevation of the mutagenicity.
authors: St. Radboud University Hospital, Nijmegen, The Netherlands.
authors: R P
authors: RP
authors: Bos
authors: C H
authors: CH
authors: van Heijst
authors: H M
authors: HM
authors: Hollanders
authors: J L
authors: JL
authors: Theuws
authors: R F
authors: RF
authors: Thijssen
authors: T K
authors: TK
authors: Eskes
mesh_terms: D001826:Body Fluids / Q000378:metabolism*; D005260:Female; D006801:Humans; D009152:Mutagenicity Tests; D009153:Mutagens / Q000378:metabolism* / Q000652:urine; D006080:Ovarian Follicle / Q000378:metabolism*; D010947:Plants, Toxic; D012016:Reference Values; D012906:Smoke / Q000032:analysis; D012907:Smoking / Q000009:adverse effects*; D014026:Nicotiana
chemical_list: D009153:Mutagens; D012906:Smoke