title: Purification and characterization of an extracellular lectin from Mycobacterium smegmatis.
abstract: Mycobacteria exist naturally in aggregated form and pathogenic strains colonize macrophages. A lectin has been isolated from the culture broth of M. smegmatis, which may, possibly, have an important role in either or both of these phenomena. The lectin of Mr 12,000-14,000 agglutinates erythrocytes from different species, and agglutination is reversed by arabinogalactan isolated from mycobacteria, as well as by yeast mannan. It has a pI of 5.5 and is rich in aspartic and glutamic acid residues.
authors: Department of Chemistry, Bose Institute, Calcutta, India.
authors: M
authors: M
authors: Kundu
authors: J
authors: J
authors: Basu
authors: P
authors: P
authors: Chakrabarti
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000818:Animals; D002850:Chromatography, Gel; D004903:Erythrocyte Aggregation / Q000187:drug effects; D005685:Galactans / Q000302:isolation & purification / Q000494:pharmacology; D006386:Hemagglutination Tests; D006801:Humans; D007525:Isoelectric Focusing; D037102:Lectins / Q000302:isolation & purification* / Q000494:pharmacology; D009161:Mycobacterium / Q000032:analysis*
chemical_list: D000596:Amino Acids; D005685:Galactans; D037102:Lectins; C005653:arabinogalactan