Interleukin-1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effect of ibuprofen.
Dinarello
C A
CA
Department of Medicine, Tufts University, Boston, MA.
Okusawa
S
S
Gelfand
J A
JA
D000818:Animals; D004357:Drug Synergism; D007022:Hypotension / Q000139:chemically induced* / Q000517:prevention & control; D007052:Ibuprofen / Q000627:therapeutic use*; D007375:Interleukin-1 / Q000633:toxicity*; D011817:Rabbits; D011994:Recombinant Proteins / Q000633:toxicity; D014409:Tumor Necrosis Factor-alpha / Q000633:toxicity*; D014655:Vascular Resistance / Q000187:drug effects
D007375:Interleukin-1; D011994:Recombinant Proteins; D014409:Tumor Necrosis Factor-alpha; D007052:Ibuprofen