title: Abnormal sperm assay tests on benzoin and caprolactam.
abstract: Benzoin and caprolactam, two noncarcinogenic chemicals found in association with consumer products, were tested in the mammalian in vivo abnormal spermhead assay. Each chemical was dissolved in a pharmaceutical grade corn oil and administered by gavage. Toxic effects were observed only with caprolactam-treated mice. Neither benzoin nor caprolactam induced a significant increase in the frequency of abnormal sperm as compared to that for animals treated only with the corn oil.
authors: Ontario Ministry of the Environment, Biohazard Laboratory, Rexdale, Canada.
authors: M F
authors: MF
authors: Salamone
mesh_terms: D000818:Animals; D001381:Azepines / Q000633:toxicity*; D001573:Benzoin / Q000633:toxicity*; D002209:Caprolactam / Q000633:toxicity*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009152:Mutagenicity Tests; D009153:Mutagens; D013094:Spermatozoa / Q000187:drug effects*
chemical_list: D001381:Azepines; D009153:Mutagens; D002209:Caprolactam; D001573:Benzoin