title: [Ultrastructural aspects in the development of the human heart. I. The cytoskeleton and motility of human embryonic myocardiocytes].
abstract: Electron microscopic investigations performed on heart tissue fragments from 12 human embryos. 8 to 15 weeks of age, showed that at the age of 8 weeks the myocardiocytes are poorly differentiated cells: they contain microfilaments of actin and myosin inserted on the cytoplasmic aspect of plasmalemma, a smooth endoplasmic reticulin and mitochondria, accounting for the early contraction. Gap junctions appear among myocardiocytes, confirming the myogenic theory of heart contractions. Within 10 to 15 weeks, actin and myosin myofilaments organize in sarcomeres. Eberth disks appear and numerous mitoses are to be seen.
authors: C
authors: C
authors: Cotrutz
authors: M
authors: M
authors: Constantinov
authors: C
authors: C
authors: Ionescu
authors: C
authors: C
authors: Cotrutz
authors: M
authors: M
authors: Moraru
authors: A
authors: A
authors: Mărgineanu
authors: L
authors: L
authors: Indrei
authors: B D
authors: BD
authors: Grigoriu
authors: G
authors: G
authors: Marta
mesh_terms: D002465:Cell Movement; D003599:Cytoskeleton / Q000648:ultrastructure*; D005865:Gestational Age; D006321:Heart / Q000196:embryology*; D006801:Humans; D008854:Microscopy, Electron; D009200:Myocardial Contraction; D009206:Myocardium / Q000648:ultrastructure*
vernacular_title: Aspects ultrastructuraux dans le developpement du coeur humain. Note I: Le cytosquelette et la motilité des myocardocytes embrionaires humaines.