Diphtheria and tetanus vaccine: a comparative study of reactogenicity.
One hundred and eighty children aged between four and six years were intensively followed-up after receiving diphtheria/tetanus vaccine. A daily diary was used as the method of assessment to elicit as many transient effects as possible. The results confirm the predicted profile of these vaccines with a high incidence of local effects but little general disturbance. The two vaccines used were essentially similar in results, showing a peak incidence of effects on Days 2-4 followed by a rapid decline in adverse effects. All the side effects reported were transient, self-limiting and did not require medical assistance.
Bryett
K A
KA
Mathews
A H
AH
Bakhshi
S S
SS
Schweiger
M S
MS
D000339:Affect; D002648:Child; D002675:Child, Preschool; D004168:Diphtheria Toxoid / Q000009:adverse effects*; D004890:Erythema / Q000209:etiology; D006801:Humans; D010146:Pain / Q000209:etiology; D013745:Tetanus Toxoid / Q000009:adverse effects*; D013997:Time Factors
D004168:Diphtheria Toxoid; D013745:Tetanus Toxoid