Postoperative zygomycetes endophthalmitis.
Fungal endophthalmitis is an uncommon complication of intraocular surgery. We report, to our knowledge, the first case of a postoperative Zygomycetes endophthalmitis that occurred after uncomplicated phacoemulsification and the insertion of a posterior chamber intraocular lens. Diagnosis, in the presence of negative aqueous and vitreous cultures, was confirmed by immunofluorescence staining of an anterior chamber inflammatory mass. Successful treatment of the eye with 20 micrograms of intraocular amphotericin B (Fungizone) may have been made possible in part by the fact that the posterior capsule remained intact, keeping the eye bicompartmental.
Orgel
I K
IK
Department of Ophthalmology, University of North Carolina, School of Medicine, Chapel Hill.
Cohen
K L
KL
D000666:Amphotericin B / Q000627:therapeutic use; D002387:Cataract Extraction; D009877:Endophthalmitis / Q000188:drug therapy / Q000209:etiology*; D005658:Fungi / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis; D011183:Postoperative Complications
D000666:Amphotericin B