[Effect of splenic humoral factors on the cholinesterase activity of liver tissue and blood serum in experimental toxic hepatitis in rats].
Activity of cholinesterase in the liver of rats with experimental toxic hepatitis decreases, while in the serum it remains unchanged. Introduction of splenin, a spleen preparation, normalizes indices of the cholinesterase activity, extract of muscles possessing no such property. Boiling-heated spleen preparation looses its activity. Activity of the studied enzyme remains unchanged both after splenectomy and splenin introduction to intact animals.
Shevchenko
A V
AV
Korpachev
V V
VV
Tychinin
V A
VA
D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000201:enzymology; D056486:Chemical and Drug Induced Liver Injury / Q000201:enzymology*; D002802:Cholinesterases / Q000378:metabolism*; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008297:Male; D009132:Muscles; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000502:physiology*; D013946:Thymopoietins / Q000494:pharmacology*; D013951:Thymus Hormones / Q000494:pharmacology*; D014020:Tissue Extracts / Q000494:pharmacology
D013946:Thymopoietins; D013951:Thymus Hormones; D014020:Tissue Extracts; C032841:thymopoietin III; D002802:Cholinesterases
Vliianie gumoral'nykh faktorov selezenki na aktivnost' kholinésterazy tkani pecheni i syvorotki krovi pri éksperimental'nom toksicheskom gepatite u krys.