title: Localization of human monoamine oxidase-A gene to Xp11.23-11.4 by in situ hybridization: implications for Norrie disease.
abstract: A cDNA for the neurotransmitter-degrading enzyme monoamine oxidase-A (MAO-A) has been assigned by in situ hybridization to the human X chromosome and subregionally localized to Xp11.23-11.4. As restriction fragments detected by this probe are deleted in some patients with Norrie disease, this assignment provides confirmation of the localization of the disease.
authors: Genetics Laboratory, Department of Biochemistry, Oxford, United Kingdom.
authors: E R
authors: ER
authors: Levy
authors: J F
authors: JF
authors: Powell
authors: V J
authors: VJ
authors: Buckle
authors: Y P
authors: YP
authors: Hsu
authors: X O
authors: XO
authors: Breakefield
authors: I W
authors: IW
authors: Craig
mesh_terms: D002871:Chromosome Banding; D002874:Chromosome Mapping; D006801:Humans; D008995:Monoamine Oxidase / Q000235:genetics*; D009693:Nucleic Acid Hybridization; D014960:X Chromosome / Q000648:ultrastructure*
chemical_list: D008995:Monoamine Oxidase