[The effect of metronidazole on the radiosensitivity of cancer of the uterine cervix].
A comparative study of the effect of rectal administration of metronidazole on radiosensitivity of cervical cancer with relation to tumor sizes and a Hb level was conducted. The effect of a direct tumor reaction on survival was investigated. Rectal administration of metronidazole proved to be effective in large tumor sizes and a low Hb level. The use of metronidazole resulted in an increase in the number of patients with complete tumor regression and an increase in their survival. A low Hb level is an independent prognostic factor in radiation therapy of cervical cancer leading to an increase in tumor radiosensitivity.
Balmukhanov
S B
SB
Aĭtkulova
Z K
ZK
Rismukhamedova
R S
RS
Abdrakhmanov
Zh N
ZhN
Revesh
L
L
D000285:Administration, Rectal; D003131:Combined Modality Therapy; D005260:Female; D006454:Hemoglobins / Q000032:analysis / Q000502:physiology; D006801:Humans; D008795:Metronidazole / Q000008:administration & dosage / Q000627:therapeutic use*; D011838:Radiation-Sensitizing Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002583:Uterine Cervical Neoplasms / Q000097:blood / Q000188:drug therapy / Q000532:radiotherapy*
D006454:Hemoglobins; D011838:Radiation-Sensitizing Agents; D008795:Metronidazole
Vliianie metronidazola na radiochuvstvitel'nost' raka sheĭki matki.