Simultaneous determination of benzene and toluene in the blood using head-space gas chromatography.
A head-space method for the simultaneous determination of benzene and toluene in blood using a gas chromatograph equipped with a photoionization detector was developed. Internal standards for benzene and toluene were fluorobenzene and o-xylene, respectively, and the detection limit was 5 nmol/l for both solvents. This method is sensitive enough for needs of biological monitoring of benzene and toluene in exposed workers. With automation it offers a possibility for routine measurements. An application of the method in monitoring exposed workers in the industry is presented.
Pekari
K
K
Institute of Occupational Health, Laboratory of Biochemistry, Helsinki, Finland.
Riekkola
M L
ML
Aitio
A
A
D001554:Benzene / Q000032:analysis* / Q000592:standards; D002849:Chromatography, Gas / Q000379:methods; D004781:Environmental Exposure; D005464:Fluorobenzenes / Q000097:blood; D006801:Humans; D008991:Monitoring, Physiologic; D012015:Reference Standards; D014050:Toluene / Q000097:blood* / Q000592:standards; D014992:Xylenes / Q000097:blood
D005464:Fluorobenzenes; D014992:Xylenes; D014050:Toluene; D001554:Benzene