Ultrastructural studies on a cadmium-storing cell in rat pancreatic tissues following cadmium chloride administration.
A new type of cell was found in the pancreatic connective tissues of rats following cadmium chloride administration. The cells contained several lipid droplets that were strongly electron-dense after the treatment with oxine, which made cadmium-oxine deposits. This suggested that the lipid droplets stored cadmium or related substances. These cells were named "cadmium-storing cells." Cadmium-storing cells are subdivided into two cell types according to their origins, "fibroblast type" and "pericyte type." The structure and function of the cadmium-storing cell were described and discussed.
Watari
N
N
Hotta
Y
Y
Mabuchi
Y
Y
D000818:Animals; D002104:Cadmium / Q000378:metabolism* / Q000493:pharmacokinetics; D019256:Cadmium Chloride; D003239:Connective Tissue Cells; D008297:Male; D008854:Microscopy, Electron; D010179:Pancreas / Q000166:cytology* / Q000378:metabolism / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains
D002104:Cadmium; D019256:Cadmium Chloride