Mental function in elderly men after surgery during epidural analgesia.
To evaluate whether there is a difference in mental function after general anaesthesia and epidural analgesia, a homogeneous group of 40 elderly men (age between 60 and 80) undergoing transurethral prostatectomy was studied. The study was prospective, randomised and double blind. Patients with all types of complications believed to impair mental function were excluded. Long-term, short-term, verbal and visual memory were tested preoperatively, and 4 days, and 3 weeks postoperatively. In conclusion, we found a significant and equal decline in test performance on the fourth postoperative day. Three weeks postoperatively, however, both groups had returned to or exceeded preoperative levels of performance.
Asbjørn
J
J
Department of Anaesthesiology, Central Hospital, Holstebro, Denmark.
Jakobsen
B W
BW
Pilegaard
H K
HK
Blom
L
L
Ostergaard
A
A
Brandt
M R
MR
D000368:Aged; D000369:Aged, 80 and over; D015360:Analgesia, Epidural; D000768:Anesthesia, General; D002045:Bupivacaine / Q000494:pharmacology; D006801:Humans; D008297:Male; D008568:Memory / Q000187:drug effects; D008606:Mental Processes / Q000187:drug effects*; D008875:Middle Aged; D011184:Postoperative Period; D011446:Prospective Studies; D011468:Prostatectomy; D011581:Psychological Tests; D011897:Random Allocation; D013997:Time Factors
D002045:Bupivacaine