[Surfactant surface activity and ultrastructural changes in the type-II alveolocytes of fetal and neonatal lungs in experimental inflammation of the maternal lungs].
The lungs of 19 guinea pigs, born from 8 females in which acute and chronic pneumonia had been modelled by transtracheal introduction of sterile fishing-line were investigated. It was established, that in guinea pigs, born in females with acute and chronic pneumonia, the functional immaturity of pneumocytes of the 2-nd type took place. The functional immaturity of pneumocytes of the 2-nd type results in suppression of the surface active characteristics of surfactant.
Zagorul'ko
A K
AK
Fat
L F
LF
Safronova
L G
LG
Kobozev
G V
GV
Gorelik
N I
NI
D000818:Animals; D000831:Animals, Newborn; D005260:Female; D005313:Fetal Death / Q000196:embryology / Q000503:physiopathology; D005325:Fetal Organ Maturity; D006168:Guinea Pigs; D008168:Lung / Q000196:embryology; D008854:Microscopy, Electron; D011014:Pneumonia / Q000196:embryology / Q000503:physiopathology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*; D011650:Pulmonary Alveoli / Q000196:embryology / Q000648:ultrastructure*; D011663:Pulmonary Surfactants / Q000032:analysis / Q000502:physiology*; D013499:Surface Properties
D011663:Pulmonary Surfactants
Sostoianie poverkhnostnoĭ aktivnosti surfaktanta i izmeneniia ul'trastruktury al'veolotsitov II tipa legkikh plodov i novorozhdennykh pri vospalenii legkikh materi v éksperimente.