Use of Pseudomonas hyperimmunoglobulin to treat septic shock in burn cases.
The progress of 18 episodes of septic shock in nine patients with burn injuries after administration of a Pseudomonas immunoglobulin is presented. In nine instances the septic shock was treated successfully. The mean burn index of these nine patients was 96. In six of the nine patients the septic shock was accompanied by simultaneous inhalation trauma and in six by acute kidney failure. In four cases the sepsis was caused by P. aeruginosa and in five by staphylococci. Despite the different causative agents, successful treatment was possible in these cases. The mean burn index for the four patients who eventually died was 119; all patients in this group were suffering from an inhalation trauma and acute kidney failure requiring dialysis. In these cases even the use of Pseudomonas immunoglobulin had no decisive effect.
Kistler
D
D
Abteilung und Lehrstuhl für Verbrennungs- und plastische, Wiederherstellungschiungschirurgie, Klinikum der RWTH Aachen, Pauwelsstr.
Piert
M
M
Kauhl
W
W
Hettich
R
R
D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000627:therapeutic use*; D001785:Blood Gas Monitoring, Transcutaneous; D002056:Burns / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D010976:Platelet Count; D011549:Pseudomonas / Q000276:immunology*; D012189:Retrospective Studies; D012772:Shock, Septic / Q000209:etiology / Q000628:therapy*; D014655:Vascular Resistance
D000907:Antibodies, Bacterial