[A new immunogenetic marker of rheumatism].
Use of monoclonal D8/17 antiserum was studied for identification of B-cell antigen in 44 rheumatic fever patients. The control group comprised healthy subjects (30) and patients suffering from rheumatoid arthritis (30), ischemic heart disease (IO); chronic tonsillitis (12) and different neoplasma of the brain (10). The preliminary genetic analysis of these patients has shown that monoclonal antiserum D8/17 can identify B-cell marker in 88-100 per cent of rheumatic fever cases.
Kilasoniia
L O
LO
Chumburidze
V B
VB
Tatishvili
N I
NI
Polianskaia
I S
IS
Tsitlanadze
V G
VG
D000293:Adolescent; D000328:Adult; D000911:Antibodies, Monoclonal; D001402:B-Lymphocytes / Q000276:immunology*; D015415:Biomarkers / Q000032:analysis*; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D007519:Isoantigens / Q000032:analysis* / Q000235:genetics; D008297:Male; D008875:Middle Aged; D012214:Rheumatic Heart Disease / Q000175:diagnosis / Q000235:genetics / Q000276:immunology*
D000911:Antibodies, Monoclonal; D015415:Biomarkers; D007519:Isoantigens
Novyĭ immunogeneticheskiĭ marker revmatizma.