Batten disease (Spielmeyer-Sjøgren disease) and haptoglobins (HP): indication of linkage and assignment to chr. 16.
In a material of 26 Caucasian families, 23 with at least 2 children affected with Batten disease, we found a lod score of 3.00 at theta = 0.00 in males and theta = 0.26 in females with haptoglobin (HP), and assign the locus for Batten disease to 16q22.
Eiberg
H
H
University Institute of Medical Genetics, Panum, Copenhagen, Denmark.
Gardiner
R M
RM
Mohr
J
J
D002885:Chromosomes, Human, Pair 16; D005260:Female; D008040:Genetic Linkage; D006242:Haptoglobins / Q000235:genetics*; D006801:Humans; D008126:Lod Score; D008297:Male; D009472:Neuronal Ceroid-Lipofuscinoses / Q000235:genetics*
D006242:Haptoglobins