[Results of impulse cytophotometry in malignant tumors of the head and neck. A prognostic parameter?].
Tumour biopsies of 93 patients with head and neck malignancy were analysed by cytophotometry. Ploidy and the proportion of cells in S-phase were measured. Tumours were classified as proliferative if the S-phase fraction was greater than 8%; the rest were classified as being less proliferative. Proliferative tumours produce local and distant metastases earlier and more frequently, so that the proportion of cells in S-phase is of prognostic importance. The response to chemotherapy of irradiation was no different in either group.
Brauneis
J W
JW
HNO-Klinik Universität Göttingen.
Laskawi
R
R
Schröder
M
M
Göhde
W
W
D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D003131:Combined Modality Therapy; D004273:DNA, Neoplasm / Q000032:analysis*; D005434:Flow Cytometry; D006258:Head and Neck Neoplasms / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007399:Interphase; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D011003:Ploidies; D011379:Prognosis
D004273:DNA, Neoplasm
Ergebnisse der Impulscytophotometrie (ICP) bei malignen Tumoren des Kopf-Hals-Bereiches. Ein prognostischer Parameter?