title: The role of toxic oxygen metabolites in interleukin-2-induced vascular leak syndrome.
abstract: We demonstrated that IL-2 causes injury by a blood mediator not by a direct action on endothelial cells and that toxic oxygen metabolites may play a role.
authors: D W
authors: DW
authors: Mulvin
authors: M A
authors: MA
authors: Grosso
authors: C A
authors: CA
authors: Kruse
authors: R B
authors: RB
authors: Howard
authors: J E
authors: JE
authors: Repine
authors: M R
authors: MR
authors: Johnston
mesh_terms: D000818:Animals; D002199:Capillary Permeability / Q000187:drug effects*; D005609:Free Radicals; D006207:Half-Life; D007376:Interleukin-2 / Q000493:pharmacokinetics*; D010100:Oxygen / Q000633:toxicity*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D005609:Free Radicals; D007376:Interleukin-2; D010100:Oxygen