Amino acid sequence of the crustacean hyperglycemic hormone (CHH) from the shore crab, Carcinus maenas.
Crustacean hyperglycemic hormone (CHH) was isolated from sinus glands of Carcinus maenas, and its primary structure was determined by manual microsequencing, using the DABITC-PITC double-coupling method. The neurohormone consists of 72 amino acid residues (8524 Da). Three disulfide bridges are present and both the N- and C-terminus are blocked. CHH does not show significant sequence homology to any known peptide hormone or protein.
Kegel
G
G
Institut für Zoophysiologie, Friedrich Wilhelms Universität, Bonn, FRG.
Reichwein
B
B
Weese
S
S
Gaus
G
G
Peter-Katalinić
J
J
Keller
R
R
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis*; D000626:Aminopeptidases; D000818:Animals; D060829:Arthropod Proteins; D003386:Brachyura; D002268:Carboxypeptidases; D002851:Chromatography, High Pressure Liquid; D004220:Disulfides / Q000032:analysis; D007447:Invertebrate Hormones / Q000032:analysis* / Q000302:isolation & purification; D013058:Mass Spectrometry; D008969:Molecular Sequence Data; D009419:Nerve Tissue Proteins / Q000032:analysis* / Q000302:isolation & purification; D010446:Peptide Fragments / Q000032:analysis; D012697:Serine Endopeptidases
D000596:Amino Acids; D060829:Arthropod Proteins; D004220:Disulfides; D007447:Invertebrate Hormones; D009419:Nerve Tissue Proteins; D010446:Peptide Fragments; C015947:hyperglycemic hormone, crustacean; D002268:Carboxypeptidases; D000626:Aminopeptidases; D012697:Serine Endopeptidases