[Genetic analysis of the predisposition to uterine myoma. Prevalence and morbidity].
Prevalence of uterine myoma (MU) was estimated in several Moscow districts. The overall average estimate of the MU prevalence is 2.45% among women of all groups. The prevalence MU estimates increase with the age, its maximum value reaching 8.31% at the age of 50 years. The morbidity risk estimates increased with the age as well, the maximum value being 2.98% at the age of 40-44 years. The value of "cumulative" morbidity risks, i. e. the probability to be affected, is 9.74% for a population living long enough, this value being based on the age-specific estimates of morbidity risks. Taking into consideration the autopsy data, indicating that frequency of MU, including small myomatous nodes, is 20%, the conclusion is made that MU is manifested by clinically expressed disturbances (urging a woman to address to a doctor) in 50% of cases only. Epidemiological data obtained are to be used later for genetic analysis of familial data on MU.
Kurbanova
M Kh
MKh
Koroleva
A G
AG
Sergeev
A S
AS
D000328:Adult; D000367:Age Factors; D000368:Aged; D015984:Causality; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000453:epidemiology / Q000235:genetics*; D008875:Middle Aged; D014586:USSR; D014594:Uterine Neoplasms / Q000453:epidemiology / Q000235:genetics*
Geneticheskiĭ analiz struktury predraspolozheniia k miome matki. Rasprostrannost' i zabolevaemost'.