Woven carbon-fibre patch versus Dacron mesh in the repair of experimental defects in the lumbar fascia of rabbits.
Defects were created in the lumbar fascia of adult New Zealand white rabbits and repaired with either woven carbon-fibre or Dacron mesh. The histological and mechanical properties of the two materials were compared at intervals up to 12 wk post-operatively. Microscopy showed an abundant orderly deposition of collagen highly vascularized with a minimal inflammatory response on the carbon fibre, whereas the Dacron mesh induced the formation of a flimsy collagenous capsule, with a marked inflammatory response. Mechanical testing showed a significant increase in the strength of the carbon-fibre patch after 2 wk (P = .001), the patch becoming much stronger than the Dacron mesh (P = .002) 5 to 12 wk after implantation.
Ward
R
R
Department of Surgery, Dryburn Hospital Durham, UK.
Minns
R J
RJ
D000818:Animals; D002244:Carbon; D003094:Collagen / Q000096:biosynthesis / Q000502:physiology; D005205:Fascia / Q000648:ultrastructure; D000071938:Fasciotomy; D008297:Male; D010795:Phthalic Acids; D011092:Polyethylene Glycols; D011093:Polyethylene Terephthalates; D019736:Prostheses and Implants; D011817:Rabbits; D013526:Surgical Mesh; D013718:Tensile Strength
D010795:Phthalic Acids; D011093:Polyethylene Terephthalates; C025539:Lavsan; D011092:Polyethylene Glycols; D002244:Carbon; D003094:Collagen