What is the significance of the binding of proteoglycans to amyloid?
While proteoglycans seem to bind to amyloids, the consequence of this binding on amyloid formation or deposition is unknown. The hypothesized roles of this binding that were suggested by Drs. Snow and Wight are discussed and other potential roles are addressed.
Caputo
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ICI Pharmaceuticals Group, ICI Americans Inc., Wilmington, DE 19897.
D000544:Alzheimer Disease / Q000378:metabolism*; D006801:Humans; D011509:Proteoglycans / Q000378:metabolism* / Q000502:physiology
D011509:Proteoglycans