[A method of immunodiagnosis of myasthenia gravis].
A high-sensitive "immune" proserine++ test was developed for the early detection of myasthenia, especially of its concealed and unclear forms. The results are derived from counting Ach-ROK immune to blood acetylcholine (Ach) before and 30 min after subcutaneous proserin administration. A high (over 10%) baseline Ach-ROK blood count which fell sharply after proserin injection was characteristic of myasthenia patients as compared to controls (under 10%). The reverse was found in healthy individuals and patients with other nervous diseases: an increase of ROK up to 24-39%.
Bykova
A A
AA
Garishina
M F
MF
Shutov
A A
AA
Iushkova
T A
TA
D000109:Acetylcholine / Q000097:blood / Q000276:immunology; D000328:Adult; D000368:Aged; D004912:Erythrocytes / Q000187:drug effects / Q000276:immunology*; D005260:Female; D006801:Humans; D007114:Immunization; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000175:diagnosis* / Q000276:immunology; D009388:Neostigmine; D012397:Rosette Formation / Q000379:methods*
D009388:Neostigmine; D000109:Acetylcholine
Sposob immunodiagnostiki miastenii.