[The effect of the hemocoagulation status in hemodialyzed patients on the patency of arteriovenous fistulas].
In a group of regularly haemodialyzed patients the authors examined 15 who suffered from repeated obliterations of subcutaneous a-v fistulae and compared the results with findings in 14 patients before the establishment of the first fistula which did not become obliterated for a period of six months. The group of patients with repeated obliterations had a significantly lower level of antithrombin III, a higher number of thrombocytes with an increased aggregation induced by low concentrations of adenosine diphosphate and adrenaline. The authors assume that investigation of coagulation mechanisms in frequent obliterations of subcutaneous a-v fistulae can help towards therapeutic prevention and as a model situation for the investigation of the development of thrombosis in general.
Charvát
J
J
Kestlerová
M
M
Spánková
H
H
Jarosová
H
H
Horácková
O
O
Tolman
V
V
König
J
J
D000328:Adult; D000990:Antithrombin III / Q000032:analysis; D001166:Arteriovenous Shunt, Surgical; D001777:Blood Coagulation; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation; D006435:Renal Dialysis; D014654:Vascular Patency
D000990:Antithrombin III; D005340:Fibrinogen
Vliv hemokoagulacního stavu hemodialyzovaných nemocných na průchodnost arteriovenózních pístĕlí.