title: Renal cortical tumors. Cytogenetic characterization.
abstract: The authors examined three cortical tumors (adenomas) of the kidney and found a consistent chromosome pattern. A combination of chromosome abnormalities (+7, +7, +17, -Y) was shared by these tumors. In contrast, none of them showed alterations of chromosome 3p and 5q, the most common changes in renal cell carcinomas. The chromosome abnormalities in these patients may define a subgroup of renal tumors, so-called adenomas, that cannot be distinguished easily from adenocarcinomas in histopathologic examination.
authors: Cancer Center, Southwest Biomedical Research Institute, Scottsdale, Arizona 85251.
authors: P
authors: P
authors: Dal Cin
authors: J
authors: J
authors: Gaeta
authors: R
authors: R
authors: Huben
authors: F P
authors: FP
authors: Li
authors: G R
authors: GR
authors: Prout
authors: A A
authors: AA
authors: Sandberg
mesh_terms: D000236:Adenoma / Q000235:genetics* / Q000473:pathology; D000368:Aged; D002872:Chromosome Deletion; D002878:Chromosomes, Human, Pair 1; D002881:Chromosomes, Human, Pair 12; D002886:Chromosomes, Human, Pair 17; D002891:Chromosomes, Human, Pair 21; D002897:Chromosomes, Human, Pair 7; D003937:Diagnosis, Differential; D005870:Giant Cell Tumors / Q000235:genetics / Q000473:pathology; D006801:Humans; D007621:Karyotyping; D007672:Kidney Cortex / Q000473:pathology*; D007680:Kidney Neoplasms / Q000235:genetics* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009006:Monosomy; D014314:Trisomy; D014998:Y Chromosome