title: Epidemiologic study of 4684 hospital-acquired infections in pediatric patients.
abstract: During a 4-year period 4684 nosocomial infections occurred in a university pediatric hospital which admitted 78,120 patients (nosocomial infection rate (NIR) = 6.0). NIR varied from 0.17 to 14.0 on different wards or services; the highest rates (greater than or equal to 5.6) were found in the Neonatal Intensive Care Unit, infant neurosurgery, hematology/oncology, neonatal surgery, cardiology/cardiovascular surgery, Pediatric Intensive Care Unit and infant/toddler medicine areas. Infections were most common in patients less than or equal to 23 months (NIR = 11.5), were less common in the 2- to 4-year age group (NIR = 3.6) and occurred least frequently in patients greater than or equal to 5 years (NIR = 2.6). The median day of onset of infections was 15.3 days. The proportional frequencies of infections were: 35% gastrointestinal; 21% bacteremia; 16% respiratory (10% upper, 6% lower); 7% postoperative wound; 6% urinary tract; 5% skin (32% of these skin infections were related to intravascular lines); 5% eye; 3% cerebrospinal fluid; and 2% other. A similar proportional frequency of 379 infections in patients hospitalized for more than 100 days was observed. The etiologic agents were Gram-positive bacteria (50%), viruses (23%), Gram-negative bacteria (18%), fungi (4%) and mixed/other (5%).
authors: Division of Infectious Diseases, Hospital for Sick Children, Toronto, Ontario, Canada.
authors: E L
authors: EL
authors: Ford-Jones
authors: C M
authors: CM
authors: Mindorff
authors: J M
authors: JM
authors: Langley
authors: U
authors: U
authors: Allen
authors: L
authors: L
authors: Nàvàs
authors: M L
authors: ML
authors: Patrick
authors: R
authors: R
authors: Milner
authors: R
authors: R
authors: Gold
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002493:Central Nervous System Diseases / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003428:Cross Infection / Q000453:epidemiology*; D015817:Eye Infections / Q000453:epidemiology; D005767:Gastrointestinal Diseases / Q000453:epidemiology; D006757:Hospital Units; D006776:Hospitals, Pediatric; D006785:Hospitals, University; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009864:Ontario / Q000453:epidemiology; D011446:Prospective Studies; D012141:Respiratory Tract Infections / Q000453:epidemiology; D018805:Sepsis / Q000453:epidemiology; D012874:Skin Diseases, Infectious / Q000453:epidemiology; D013530:Surgical Wound Infection / Q000453:epidemiology; D014552:Urinary Tract Infections / Q000453:epidemiology