Peak expiratory flow rate in an elderly population.
A population survey was conducted in 1982-1983 among 3,812 persons aged 65 years and older residing in East Boston, Massachusetts, a geographically defined urban community. Three measurements of peak expiratory flow rate were obtained by using calibrated mini-Wright meters. Peak expiratory flow rate was strongly related to age, sex, smoking, and years smoked. After adjustment for these factors, low peak expiratory flow rate was associated with chronic respiratory symptoms (cough, wheeze, shortness of breath, exertional dyspnea, orthopnea, and paroxysmal nocturnal dyspnea; p less than 0.0001) and with certain cardiovascular variables (history of stroke, p = 0.0014; angina, p = 0.05; and high pulse rate, p = 0.004). No significant associations were found with history of myocardial infarction or systolic and diastolic blood pressures. Peak expiratory flow rate was positively related to education (p less than 0.0001) and income (p less than 0.0001). Peak expiratory flow rate also was strongly related (p less than 0.0001) to measures of functional ability and physical activity, self-assessment of health, and simple measures of cognitive function. The correlations of peak expiratory flow rate with pulmonary symptoms and other indices of chronic disease raise the possibility that peak expiratory flow rate will predict mortality in an elderly population.
Cook
N R
NR
Department of Medicine, Brigham and Women's Hospital, Boston, MA.
Evans
D A
DA
Scherr
P A
PA
Speizer
F E
FE
Vedal
S
S
Branch
L G
LG
Huntley
J C
JC
Hennekens
C H
CH
Taylor
J O
JO
D000367:Age Factors; D000368:Aged; D001900:Boston; D002318:Cardiovascular Diseases / Q000453:epidemiology; D015331:Cohort Studies; D003710:Demography; D005260:Female; D005540:Forced Expiratory Flow Rates; D006306:Health Surveys; D006801:Humans; D008297:Male; D010366:Peak Expiratory Flow Rate; D012120:Respiration Disorders / Q000453:epidemiology*; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000453:epidemiology; D013997:Time Factors