title: An improved design of electrodes for measurement of streaming potentials on wet bone in vitro and in vivo.
abstract: Streaming potentials are generated by mechanical stress in wet bone and may constitute a control mechanism for bone remodeling. Measurement of streaming potentials in bone has attracted considerable effort in past years but quantitative studies have been hampered by relatively poor repeatability when using Ag.AgCl electrodes which contact bone via a wick moistened with electrolyte. Improvement now has been achieved with an electrode design that limits the specific area of contact of an agar/salt bridge by means of a silastic seal, thus permitting the same equipotential surface to be contacted for each set of measurements. This reduces variations caused by bone structure and impedance, and facilitates quantitative comparisons of the response of bone samples to selected variables. The new design also permits considerable qualitative improvement in recordings made from bone during locomotor function in experimental animals in vivo.
authors: Orthopaedic Engineering and Research Center, Helen Hayes Hospital, West Haverstraw, NY 10993.
authors: G V
authors: GV
authors: Cochran
authors: D G
authors: DG
authors: Dell
authors: V R
authors: VR
authors: Palmieri
authors: M W
authors: MW
authors: Johnson
authors: M W
authors: MW
authors: Otter
authors: M P
authors: MP
authors: Kadaba
mesh_terms: D000180:Acrylic Resins; D000200:Action Potentials; D000269:Adhesives; D000818:Animals; D001842:Bone and Bones / Q000502:physiology*; D002417:Cattle; D004285:Dogs; D004567:Electrodes, Implanted; D004867:Equipment Design; D066298:In Vitro Techniques; D012834:Silver; D013314:Stress, Mechanical; D014867:Water
chemical_list: D000180:Acrylic Resins; D000269:Adhesives; D014867:Water; D012834:Silver