title: Causes and treatment of sexually acquired genital ulceration in southern Africa.
abstract: The cause of sexually acquired genital ulceration was studied in 240 consecutive migrant mineworkers attending a sexually transmitted disease clinic in Carletonville, Transvaal. Chancroid proved to be the most common cause of genital ulcer disease, with Haemophilus ducreyi being isolated from 164 patients (68%). In 60% of cases the disease was locally acquired and in the remaining 40%, the infection was acquired in Lesotho, Botswana, Natal, Transkei and Malawi. Syphilis was diagnosed in 62 patients (26%), lymphogranuloma venereum in 16 (7%), genital herpes in 8 (3%) and granuloma inguinale in 1. No cause of ulceration could be found in 31 patients (13%). Mixed infections were documented in 41 patients (17%). Diagnosis of the cause of genital ulcer disease is not possible without relatively sophisticated laboratory support; however, simplified strategies for management and treatment have been developed.
authors: MRC Emergent Pathogen Research Unit, School of Pathology, University of the Witwatersrand, Johannesburg.
authors: Y
authors: Y
authors: Dangor
authors: G
authors: G
authors: Fehler
authors: F D
authors: FD
authors: Exposto
authors: H J
authors: HJ
authors: Koornhof
mesh_terms: D000328:Adult; D001741:Black or African American; D044383:Black People; D005832:Genital Diseases, Male / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008906:Mining; D012749:Sexually Transmitted Diseases / Q000453:epidemiology; D013019:South Africa / Q000453:epidemiology; D014456:Ulcer / Q000209:etiology*