[Biologic significance and clinical value of carcinoembryonic antigen in tissues in transitional cell carcinoma of the urinary tract].
Avidin-biotin complex immuno-histochemical technique with monoclonal antibody to CEA was used to study comparatively relationship of expression of carcinoembryonic antigen in tumor tissue of 82 patients with transitional cell carcinoma (TCC) of upper tract and bladder with prognosis of the patients with TCC and its biologic significance. Our study showed that the detection of CEA in patients with transitional cell carcinoma of upper tract could reflect subsequent recurrence and survival of the patients and related with histologic grade (P less than 0.01). But the expression of CEA in patients with bladder tumor was not related with the clinical course of the patients and the histologic grade (P greater than 0.05).
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D000911:Antibodies, Monoclonal / Q000032:analysis; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D002295:Carcinoma, Transitional Cell / Q000276:immunology*; D006801:Humans; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D001749:Urinary Bladder Neoplasms / Q000276:immunology; D014571:Urologic Neoplasms / Q000276:immunology*
D000911:Antibodies, Monoclonal; D002272:Carcinoembryonic Antigen