[Immunologic aspects of the macrophages in the milk of preterm mothers].
Number and function of milk macrophages from 25 healthy mothers delivering preterm (PHMMo) (mean gestational age 33 weeks) were compared with those obtained from 74 mothers with term delivery (THMMo). The average concentration of MMø in colostrum did not differ among both sources: 0.55 x 10(6)/ml (PHMMo) and 0.42 x 10(6)/ml (THMMo). The mean phagocytic index of PHMMo (3.35 yeasts/cell) and THMMo (3.40 yeasts/cell) was similar (p greater than 0.05); both cell types were significantly higher than control monocytes (CMo) (1.95 yeasts/cell) (p less than 0.001). The mean chemotactic function of PHMMo (11.58 cells/field) was significantly greater than THMMo (2.75 cells/field) (p less than 0.001). However, both milk cells showed lower chemotaxis than CMo (32.63 cells/field) (p less than 0.001).
Rodríguez Rodríguez
M C
MC
Servicio de Pediatría, Hospital Universitario San Carlos, Madrid.
Subiza Garrido-Lestache
J L
JL
Mateos Burguillo
P
P
Casado de Frias
E
E
Moro Serrano
M
M
Gómez de la Concha
E
E
D000328:Adult; D002630:Chemotactic Factors / Q000502:physiology*; D003126:Colostrum / Q000166:cytology*; D005260:Female; D006801:Humans; D008264:Macrophages / Q000276:immunology*; D008895:Milk, Human / Q000166:cytology*; D007752:Obstetric Labor, Premature / Q000503:physiopathology*; D011247:Pregnancy
D002630:Chemotactic Factors
Aspectos inmunológicos de los macrófagos de leche de madre pretérmino.