How to manage other risk factors in patients with hypertension.
High blood pressure is unquestionably a risk factor for premature morbidity and mortality, especially from coronary artery disease and stroke. Risk of clinical manifestations of coronary artery disease increases dramatically if other risk factors, such as a history of cigarette smoking, hypercholesterolemia, left ventricular hypertrophy, and diabetes, are present in addition to hypertension. Therefore, management must include measures to control these risk factors as well as reduce blood pressure. In patients with hypercholesterolemia or diabetes, some antihypertensive drugs must be used with extreme caution or avoided altogether because of possible side effects. Although systolic pressure is an important prognostic factor, there is currently no evidence that treatment of isolated systolic hypertension is beneficial.
Borhani
N O
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Department of Community Health, University of California, Davis 95616.
D000959:Antihypertensive Agents / Q000627:therapeutic use; D003327:Coronary Disease / Q000209:etiology*; D003925:Diabetic Angiopathies / Q000628:therapy; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications / Q000628:therapy; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology*; D011379:Prognosis; D012307:Risk Factors; D013599:Systole
D000959:Antihypertensive Agents