Cutaneous Bipolaris spicifera infection.
Bipolaris spicifera is a dematiaceous fungus that has rarely been reported to cause cutaneous infection in humans. A patient with leukemia was examined for a non-healing ulcer on her leg that developed following minor trauma. Histopathologic study revealed groups of nonpigmented, septate fungal hyphae located predominantly in the necrotic ulcer base. Cultures of a biopsy specimen yielded colonies that were gray to black with a black reverse. Microscopic examination revealed dematiaceous, straight, oblong conidia consistent with B spicifera. The ulcer was successfully treated with surgical excision, skin graft, and amphotericin B.
Straka
B F
BF
Department of Dermatology, University of Virginia Health Sciences Center, Charlottesville 22908.
Cooper
P H
PH
Body
B A
BA
D000328:Adult; D000842:Ankle; D003881:Dermatomycoses / Q000150:complications; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000150:complications; D015470:Leukemia, Myeloid, Acute / Q000150:complications; D003904:Mitosporic Fungi