title: Varicella-zoster virus infections in children infected with human immunodeficiency virus.
abstract: Primary varicella-zoster (VZ) infection in eight children with perinatally acquired human immunodeficiency virus infection tended to be severe, prolonged, complicated by bacterial infections and in one case fatal. Depletion of CD4-lymphocytes was associated with chronic and recurrent VZ infection. In some patients convalescent VZ antibody titers were low and did not correlate with recurrence of VZ lesions. Administration of acyclovir appeared to be beneficial in suppressing VZ in human immunodeficiency virus-infected children with primary or recurrent VZ infection.
authors: Department of Pediatrics, New York University Medical Center, NY 10016.
authors: E
authors: E
authors: Jura
authors: E G
authors: EG
authors: Chadwick
authors: S H
authors: SH
authors: Josephs
authors: S P
authors: SP
authors: Steinberg
authors: R
authors: R
authors: Yogev
authors: A A
authors: AA
authors: Gershon
authors: K M
authors: KM
authors: Krasinski
authors: W
authors: W
authors: Borkowsky
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000150:complications; D002644:Chickenpox / Q000150:complications* / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006525:Hepatitis, Viral, Human / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007223:Infant; D008297:Male; D011024:Pneumonia, Viral / Q000150:complications* / Q000188:drug therapy; D012008:Recurrence
chemical_list: D000212:Acyclovir