[Evaluation of glycosuria in normal glucose tolerance].
In 52 subjects where after 10.6 +/- 7 years after detection of glycosuria on fasting normal glucose tolerance persists some risk factors and early biochemical changes indicating possible later development of diabetes were evaluated. 73% of the subjects had a positive family-history of diabetes and 61% were obese. In 42% of the subjects during the present examination glucose in urine was detected only after a glucose load. In 35% of the subjects pathological serum values of glycoproteins were found and their mean fasting blood sugar levels and levels 60 minutes after a glucose load were significantly higher, although in the range of normal oGTT, as compared with the group with normal glycoprotein levels. 21% had pathological values of N-acetyl-beta-D-glucosaminidase levels in serum and urine and concurrently significantly higher IRI values 60 and 120 minutes after a glucose load, than the group with a normal value. In obese subjects, as compared with those with a normal body weight, there were significantly higher mean blood sugar levels on fasting and 60 minutes after a glucose load and the same applies to IRI levels on fasting and after 60 minutes following stimulation. The authors discuss the causes and interrelations of the assembled results.
Polácková
H
H
Platilová
H
H
Svoboda
Z
Z
Stolba
P
P
D000328:Adult; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000652:urine; D005260:Female; D005951:Glucose Tolerance Test; D006029:Glycosuria; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000378:metabolism / Q000652:urine
Hodnocení glykosurie pri normální glukózové toleranci.