[Significance of the hippocampus in the development of convulsive syndrome by kindling electrostimulation of the caudate nucleus].
The experiments were conducted on rabbits with chronically implanted electrodes (neocortex, hippocampus, amygdala, caudate nucleus). The rostral part of caudate nucleus was stimulated once daily at a current maximum 300 microA, using 60 Hz square pulses (1.0 Ms) 12.0 s in duration. The severity of motor seizures and its developmental velocity were studied in the relation with a degree of the epileptization of the brain. The data obtained illustrated the next relation: the more stable and intensive were discharges in hippocampus the harder motor seizures.
Timofeeva
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D000818:Animals; D002421:Caudate Nucleus / Q000503:physiopathology*; D004558:Electric Stimulation; D004569:Electroencephalography; D006624:Hippocampus / Q000503:physiopathology*; D007696:Kindling, Neurologic; D011817:Rabbits; D012640:Seizures / Q000503:physiopathology*; D013577:Syndrome
Znachenie gippokampa v razvitii sudorozhnogo sindroma pri kindling-élektrostimuliatsiiakh khvostatogo iadra.