title: [Rectal stenosis due to long-term therapy with ergotamine].
abstract: Two patients (a woman aged 39, a man aged 46 years) had developed severe distal rectal stenoses after 20 years of anti-migraine treatment with ergotamine-containing suppositories. The woman required several bougie and laser treatments. In the man a megacolon had developed due to increasing, finally complete, rectal stenosis and this required a double colostomy (transverse colon) as an emergency. Ergotamine-containing suppositories are widely used in the treatment of migraine, but they should not be administered for prolonged periods.
authors: Medizinische Klinik, Universität Düsseldorf.
authors: J
authors: J
authors: Ontyd
authors: J F
authors: JF
authors: Erckenbrecht
authors: W
authors: W
authors: Berges
mesh_terms: D000328:Adult; D003125:Colostomy; D004106:Dilatation; D004878:Ergotamine / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008297:Male; D008531:Megacolon / Q000209:etiology* / Q000601:surgery; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy; D012002:Rectal Diseases / Q000139:chemically induced* / Q000150:complications / Q000601:surgery; D013488:Suppositories
chemical_list: D013488:Suppositories; D004878:Ergotamine
vernacular_title: Rektumstenosen bei Langzeittherapie mit Ergotamin.