title: Circulating plasma alpha-tocopherol following a single injection in a black rhinoceros (Diceros bicornis).
abstract: Injectable all rac-alpha-tocopherol, at a dose of 12.4 IU/kg body mass, increased circulating levels of alpha-tocopherol in the black rhinoceros (Bicornis diceros) from 0.18 microgram/ml to 1.47 micrograms/ml within 2 hr. Although the plasma level peaked at Day one (13.07 micrograms/ml) and dropped rapidly, substantial residual effects were seen even 10 days (1.50 micrograms/ml) following a single injection. It appears that parenteral vitamin E administration may be suitable for therapeutic treatment of vitamin E deficiency in the black rhinoceros.
authors: Animal Health Center, New York Zoological Society, Bronx, New York 10460.
authors: E S
authors: ES
authors: Dierenfeld
authors: S B
authors: SB
authors: Citino
mesh_terms: D000818:Animals; D005260:Female; D007273:Injections, Intramuscular / Q000662:veterinary; D010527:Perissodactyla / Q000097:blood / Q000378:metabolism*; D014810:Vitamin E / Q000008:administration & dosage / Q000097:blood* / Q000493:pharmacokinetics
chemical_list: D014810:Vitamin E