Rectal induction of anaesthesia in children. A comparison between ketamine-midazolam and halothane for induction and maintenance of anaesthesia.
Thirty children were randomly allocated to one of three anaesthetic techniques. Rectal anaesthesia induction with a mixture of ketamine 10 mg.kg-1 BW and midazolam 0.2 mg.kg-1 BW and maintenance of anaesthesia with either intravenous ketamine or halothane were compared to induction and maintenance with halothane. Rectal induction was found reliable and useful. The frequency of side effects, the recovery time, and the time until the child could be discharged were similar in the groups maintained with halothane, whereas recovery was prolonged when intravenous ketamine was used for maintenance.
Holm-Knudsen
R
R
Department of Anesthesia, Gentofte Hospital, University of Copenhagen, Denmark.
Nygård
E
E
Laub
M
M
D000769:Anesthesia, Inhalation; D000774:Anesthesia, Rectal; D002648:Child; D002652:Child Behavior; D002675:Child, Preschool; D005260:Female; D006212:Hallucinations / Q000139:chemically induced; D006221:Halothane / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D007649:Ketamine / Q000008:administration & dosage / Q000009:adverse effects; D008297:Male; D008874:Midazolam / Q000008:administration & dosage / Q000009:adverse effects; D011897:Random Allocation; D013997:Time Factors
D007649:Ketamine; D008874:Midazolam; D006221:Halothane