Formation of infectious hybrid virions with gibbon ape leukemia virus and human T-cell leukemia virus retroviral envelope glycoproteins and the gag and pol proteins of Moloney murine leukemia virus.
The gibbon ape leukemia virus, SEATO strain, and human T-cell leukemia virus type I envelope glycoproteins can be functionally assembled with a Moloney murine leukemia virus core into infectious particles. The envelope-host cell receptor interaction is the major determinant of the host cell specificity for these hybrid virions.
Wilson
C
C
Laboratory of Tumor Cell Biology, National Institute of Cancer, Bethesda, Maryland 20892.
Reitz
M S
MS
Okayama
H
H
Eiden
M V
MV
D000818:Animals; D002460:Cell Line; D003001:Cloning, Molecular; D004274:DNA, Recombinant; D015683:Gene Products, gag; D006678:HIV / Q000502:physiology*; D015368:Human T-lymphotropic virus 1 / Q000502:physiology*; D006922:Hylobates / Q000382:microbiology; D008562:Membrane Glycoproteins / Q000502:physiology; D051379:Mice; D008979:Moloney murine leukemia virus / Q000502:physiology* / Q000648:ultrastructure; D012190:Retroviridae / Q000502:physiology* / Q000648:ultrastructure; D012191:Retroviridae Proteins / Q000502:physiology*; D014759:Viral Envelope Proteins / Q000502:physiology*
D004274:DNA, Recombinant; D015683:Gene Products, gag; D008562:Membrane Glycoproteins; D012191:Retroviridae Proteins; D014759:Viral Envelope Proteins