Dark adaptation compared with electrooculography in primary biliary cirrhosis.
In a series of asymptomatic patients with primary biliary cirrhosis there was a significant impairment of dark adaptation thresholds as compared with a control group. Vitamin A levels were abnormally low in only two of the patients and these two both showed high dark adaptation thresholds. The electrooculogram was reduced in only the most severely affected case. It is suggested that visual function tests should be performed alongside vitamin A level measurements before deciding on treatment.
Barber
C
C
University Hospital Nottingham, UK.
Brimlow
G
G
Galloway
N R
NR
Toghill
P
P
Walt
R P
RP
D000328:Adult; D000368:Aged; D003623:Dark Adaptation; D004585:Electrooculography; D005260:Female; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D008875:Middle Aged; D009755:Night Blindness / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D012684:Sensory Thresholds; D014787:Vision Tests; D014792:Visual Acuity; D014801:Vitamin A / Q000097:blood / Q000627:therapeutic use
D014801:Vitamin A