[Effect of physical exercise on the fate of drugs in the body].
A data from the literature on the effect of physical exercise on the fate of drugs in the body have been collected. An intensive exercise and training produce several important changes in the physiological and metabolic function of the tissues and organs, especially kidneys, liver and circulatory system. Therefore, absorption, metabolism, and elimination of numerous drugs are modified. An intensive physical exercise increases or decreases blood levels of drugs and effect their elimination. It should be stressed that the data on these problems are incomplete and related to various groups of drugs, different modes of application, and various models of exercise testing. It seems, however, that physical exercise should be considered and additional, besides genetic factors, diet or patient's age, factor affecting the fate of drugs in the body.
Lutosławska
G
G
Górski
J
J
D015444:Exercise; D006801:Humans; D010599:Pharmacokinetics
Wpływ wysiłku fizycznego na losy leków w organizmie.