title: [The effect of asynchronous contraction of the myocardium on its mechanical function].
abstract: The effect of asynchronous excitation of adjacent portions of intact myocardium was simulated in two parallel connected papillary muscles from the rabbit heart right ventricle. Mechanical characteristics (length-force, force-rate, final systolic length-specific time of relaxation) of each of the muscles were recorded in simultaneous and asynchronous contractions. The asynchronism was found to exert a positive inotropic effect in each of the muscles and a negative one in the duplex. The asynchronism decelerated the temporal course of relaxation both in separate muscles and in duplex. The asynchronism-related mechanochemical dissociation seems to be the crucial phenomenon underlying the whole cycle of the mechanical phenomena.
authors: F A
authors: FA
authors: Bliakhman
authors: V S
authors: VS
authors: Markhasin
authors: Kh M
authors: KhM
authors: Nafikov
authors: V Ia
authors: VIa
authors: Izakov
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D004558:Electric Stimulation; D006321:Heart / Q000502:physiology*; D066298:In Vitro Techniques; D009200:Myocardial Contraction / Q000502:physiology*; D010210:Papillary Muscles / Q000502:physiology; D011817:Rabbits; D013997:Time Factors
vernacular_title: Vliianie asinkhronnogo sokrashcheniia miokarda na ego mekhanicheskuiu funktsiiu.