[Experimental study on embryo cerebellar tissue transplantation in repairing transection injury of spinal cord].
Transplantation of cerebellar tissue to the transection part of the spinal cord was performed on 48 dogs. Among them, 35 dogs were transplanted with cultured cerebellar tissue, 7 of which resumed standing and walking ability, 13 dogs were transplanted with embryo cerebellar tissue and 7 resumed standing and walking (58.3%). In the control group of 8 dogs, no recover was found. Histological examination and HRP reaction showed that (1) embryo cerebellar tissue may prevent the scar formation and neuroglia proliferation; (2) some neurofibers existed in the scar tissue between the two ends of transected spinal cord; (3) the connection of the grafting material and the host was established by special target.
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D000818:Animals; D002531:Cerebellum / Q000637:transplantation*; D046508:Culture Techniques; D004285:Dogs; D004622:Embryo, Mammalian; D005260:Female; D013119:Spinal Cord Injuries / Q000473:pathology / Q000601:surgery*