[BCG vaccination in low risk tuberculosis; first experiences after the suspension of BCG vaccination of newborns in Czechoslovakia].
With the steadily declining risk of tuberculosis infection in CSR the question arose whether vaccination of infants remains worthwhile considering not only resources spent but also complications to vaccination vis-a-vis benefits derived. A prospective study has been designed in which BCG vaccination of newborns is discontinued in an area with 30,000 newborns yearly. In the period from April 1, 1986 to January 31, 1988 there were not vaccinated 43,428 children (84.8% of the newborns). The collaboration of mothers was good. The one year old non-vaccinated children were tested with 2 TU PPD RT 23 with Tween 80. The distribution of positive tuberculin reactions appears unimodal, relatively large reactions being absent. 8 children had reactions with 6 or more mm induration. That corresponds to a risk of infection of 0.04%. The project continues in the research area and might be extended to another area.
Trnka
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Forschungsnstitut für Tuberkulose und Lungenkrankheiten Prag/CSSR.
Danková
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D
D001500:BCG Vaccine; D003604:Czechoslovakia; D006801:Humans; D007231:Infant, Newborn; D011446:Prospective Studies; D012307:Risk Factors; D014376:Tuberculosis / Q000517:prevention & control*; D014611:Vaccination
D001500:BCG Vaccine
BCG-Schutzimpfungen bei niedrigem Tuberkulose-Erkrankungsrisiko; erste Erfahrungen nach dem Aussetzen der BCG-Neugeborenen-Impfung in der CSR.