title: Inhibition of infectivity of human immunodeficiency virus by a novel nucleoside, oxetanocin, and related compounds.
abstract: Oxetanocin is a novel nucleoside containing a 4-membered sugar, oxetanosyl-N-glycoside, and adenine. The effects of oxetanocin and related compounds on the infectivity of human immunodeficiency virus (HIV) were examined. They inhibited HIV infectivity in vitro. Allopurinol and mycophenolic acid produced additive anti-HIV effects when added with these compounds.
authors: Department of Hygiene, Gumma University School of Medicine, Japan.
authors: J
authors: J
authors: Seki
authors: N
authors: N
authors: Shimada
authors: K
authors: K
authors: Takahashi
authors: T
authors: T
authors: Takita
authors: T
authors: T
authors: Takeuchi
authors: H
authors: H
authors: Hoshino
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives* / Q000032:analysis / Q000494:pharmacology; D000493:Allopurinol / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000032:analysis / Q000494:pharmacology*; D002478:Cells, Cultured; D002851:Chromatography, High Pressure Liquid; D006678:HIV / Q000187:drug effects / Q000472:pathogenicity*; D006801:Humans; D066298:In Vitro Techniques; D009173:Mycophenolic Acid / Q000494:pharmacology; D013601:T-Lymphocytes / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; C051061:oxetanocin; D000493:Allopurinol; D009173:Mycophenolic Acid; D000225:Adenine