[Nail pigmentation caused by azidothymidine].
Azidothymidine is a new antiviral drug that acts by competitive inhibition of reverse transcriptase of retroviruses. Azidothymidine is now widely used in treatment of patients with AIDS or ARC; the most important side effects of this drug are anaemia and neutropenia. Recently pigmentary changes of the nails (diffuse pigmentation and longitudinal or transverse bands) provoked by azidothymidine-treatment have also been reported. We describe a such case.
Depaoli
M A
MA
Bedello
P G
PG
Tamponi
M
M
D006679:HIV Seropositivity / Q000150:complications / Q000188:drug therapy; D006467:Hemophilia A / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D009260:Nail Diseases / Q000139:chemically induced*; D010859:Pigmentation Disorders / Q000139:chemically induced*; D015215:Zidovudine / Q000009:adverse effects* / Q000627:therapeutic use
D015215:Zidovudine
Pigmentazione ungueale indotta da azidotimidina.