In vitro activity of lomefloxacin (SC 47111 or NY-198) against Chlamydia trachomatis strains.
The in vitro activity of lomefloxacin (SC 47111 or NY-198), a new quinolone antibiotic, against 11 strains of Chlamydia trachomatis was determined and compared to doxycycline, norfloxacin, and ciprofloxacin. Lomefloxacin had anti-chlamydial activity comparable to that of ciprofloxacin. (MIC and MBC90, 2 micrograms/ml).
Segreti
J
J
Department of Medicine, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612.
Kessler
H A
HA
Kapell
K
K
Trenholme
G M
GM
D000890:Anti-Infective Agents / Q000494:pharmacology*; D002692:Chlamydia trachomatis / Q000187:drug effects* / Q000302:isolation & purification; D002939:Ciprofloxacin / Q000494:pharmacology; D004318:Doxycycline / Q000494:pharmacology; D024841:Fluoroquinolones; D006801:Humans; D008826:Microbial Sensitivity Tests; D009643:Norfloxacin / Q000494:pharmacology; D015363:Quinolones
D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D015363:Quinolones; D002939:Ciprofloxacin; C053091:lomefloxacin; D009643:Norfloxacin; D004318:Doxycycline