[The effect of lymphocytes on the growth of transplanted adenocarcinoma of the colon in mice].
The activation of spleen lymphocytes during tumour growth on the syngeneic mice has been shown. The activated lymphocytes were able to restore the tumour growth after cyclophosphane induction of immunodeficiency. Activated lymphocytes of mice acted the same way with liver regeneration and isoproterenol induction of salivary gland hyperplasia. The inhibitory effect of lymphocytes has been also shown during this process. Both stimulation and inhibition were the function of the ThyI lymphocytes. The regularities shown may reflect important processes of cell proliferation regulation in multicellular organisms.
Dontsov
V I
VI
D000230:Adenocarcinoma / Q000473:pathology*; D000818:Animals; D003110:Colonic Neoplasms / Q000473:pathology*; D003520:Cyclophosphamide / Q000633:toxicity; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology; D051379:Mice; D008815:Mice, Inbred Strains; D009368:Neoplasm Transplantation
D003520:Cyclophosphamide
Vliianie limfotsitov na rost perevivaemoĭ adenokartsinomy tolstogo kishechnika u mysheĭ.