title: Paget disease: MR imaging findings.
abstract: Magnetic resonance (MR) images of 13 patients with Paget disease were reviewed, and findings were correlated with those from computed tomographic (CT) scans, radiographs, and, in two patients, surgical biopsy. MR imaging findings correlated with CT and radiographic findings of cortical thickening, increased size of bone, and coarse thickened trabeculae. Focal or diffuse decreased signal intensity, representing dense bone, was seen on images obtained with short and long repetition times (TRs) and echo times (TEs); high-signal foci, representing fat collections, were seen on short TR/TE images; and high-signal foci, representing fibrovascular marrow in active Paget disease, were seen on long TR/TE images. Complications of Paget disease-including basilar invagination, spinal stenosis, and sarcoma--were well identified on MR images. Although MR imaging is not generally used in diagnosis of Paget disease, the disease will be encountered more frequently as more MR imaging examinations are performed. An awareness of the range of findings in Paget disease is useful in evaluating MR images of the musculoskeletal and other systems.
authors: Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104.
authors: M C
authors: MC
authors: Roberts
authors: H Y
authors: HY
authors: Kressel
authors: M D
authors: MD
authors: Fallon
authors: M B
authors: MB
authors: Zlatkin
authors: M K
authors: MK
authors: Dalinka
mesh_terms: D000368:Aged; D001842:Bone and Bones / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010001:Osteitis Deformans / Q000150:complications / Q000175:diagnosis*