title: [Incidence and prognostic significance of pulmonary artery thromboses in patients with acute respiratory failure: a study of 106 patients using bilateral pulmonary balloon occlusion angiography].
abstract: In 106 patients suffering from acute respiratory failure of different severity 157 bedside balloon occlusion pulmonary angiographic studies have been performed through a pulmonary artery catheter to assess the frequency and extent of intravascular occlusive disease. The vascular alterations in acute respiratory failure impair the prognosis essentially. The decreasing pulmonary vascular cross-section causes a greater pulmonary vascular resistance and consecutive pulmonary artery hypertension and finally right heart failure. In 33% of patients multiple thrombosis and in 15.1% singularly pulmonary artery filling defects could be shown. In 21.7% a decreased background opacification caused by extensive microthrombosis was present. Only in 30.2% the angiography was interpreted as normal. The mortality rate was significant higher in patients with multiple macro- and microthrombosis (82.9% respectively 52.2%) compared to patients with singular pulmonary artery filling defects and normal angiography (37.5% respectively 28.1%). The angiographic result was further correlated with the severity of the acute respiratory failure, the haemodynamic and haemostasiologic data, the degree of consolidation in the chest-X-ray and the post mortem angiographic studies.
authors: Department of Radiology ACC, Massachusetts General Hospital, Boston.
authors: H
authors: H
authors: Jantsch
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001780:Blood Coagulation Tests; D002648:Child; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011651:Pulmonary Artery / Q000000981:diagnostic imaging*; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging* / Q000188:drug therapy; D011669:Pulmonary Wedge Pressure / Q000187:drug effects; D011859:Radiography; D012128:Respiratory Distress Syndrome / Q000000981:diagnostic imaging* / Q000209:etiology; D012131:Respiratory Insufficiency / Q000000981:diagnostic imaging* / Q000209:etiology; D013300:Streptokinase / Q000008:administration & dosage; D014655:Vascular Resistance / Q000187:drug effects
chemical_list: D013300:Streptokinase
vernacular_title: Häufigkeit und prognostische Bedeutung pulmonalarterieller Thrombosen bei Patienten mit akutem respiratorischem Versagen: Eine Studie an 106 Patienten mittels beidseitiger pulmonaler Ballon-Verschlussangiographie.