Magnetic resonance imaging of the cerebral aqueduct. Signal intensity time curves demonstrated by fast acquisition with multiple excitation (FAME).
Using cardiac-gated fast acquisition with multiple excitation (FAME), time curves of the cerebral aqueduct signals were derived in 19 healthy volunteers and 14 patients. A mean curve of the normal subjects was determined during systole. A relatively stable point of time was found at 270 msec after the R-wave supposed to be the reversal of the flow of cerebral-spinal fluid in the aqueduct. Different curves were noticed in complete aqueductal obstruction (n = 2); in other pathologic states, such as cerebral tumor (n = 3), normal pressure hydrocephalus (n = 3), and brain atrophy (n = 1), no different signal time curves were observed. Parameters such as aqueduct diameter, cerebro-spinal fluid volume and brain compliance are probably other important factors in aqueduct liquor flow.
van den Hout
J H
JH
Department of Radiology, Utrecht University Hospital, The Netherlands.
Bakker
C J
CJ
Mali
W P
WP
van Dijk
P
P
Faber
J A
JA
Feldberg
M A
MA
Gooskens
R H
RH
Witkamp
T D
TD
D000293:Adolescent; D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000473:pathology; D002535:Cerebral Aqueduct / Q000473:pathology*; D002555:Cerebrospinal Fluid / Q000502:physiology; D004562:Electrocardiography; D006801:Humans; D006849:Hydrocephalus / Q000473:pathology; D007223:Infant; D008279:Magnetic Resonance Imaging / Q000379:methods; D008875:Middle Aged