Bias arising in case-control studies from selection of controls from overlapping groups.
Three examples are used to demonstrate that the selection of controls from categories that overlap can lead to bias. Case-control studies that use friend controls and the practice of age-matching controls to cases within a specified number of years (caliper matching) are examples of the selection bias described in the paper. The bias resulting from the use of friend controls can be large and, since the use of friend controls is common, this source of bias is of considerable practical consequence. The use of friend controls or the selection of controls according to other variables with categories that overlap should be avoided.
Austin
H
H
Department of Epidemiology, School of Public Health, University of Alabama, Birmingham 35294.
Flanders
W D
WD
Rothman
K J
KJ
D000367:Age Factors; D015982:Bias; D016022:Case-Control Studies; D015988:Cohort Effect; D006801:Humans; D015983:Selection Bias