Alpha 1-antitrypsin phenotypes in homosexual men.
The alpha 1-antitrypsin (AAT) phenotype was determined by isoelectric focusing in 215 male homosexuals and compared with those in 208 male heterosexuals. The incidence of abnormal phenotypes was 16.3% in the homosexual group which was significantly different (p less than 0.03) than the 8.7% in the heterosexual group. There was no difference in the phenotype distribution between homosexuals who were anti-human immunodeficiency virus reactive and those who were non-reactive. It suggests that investigation into the interplay of factors associated with homosexuality could include genetic as well as psychological and social factors.
Deam
D R
DR
Biochemistry Department, Royal Melbourne Hospital.
Byron
K A
KA
Ratnaike
S
S
Campbell
D G
DG
Mulhall
B P
BP
Mackay
I R
IR
D006679:HIV Seropositivity / Q000097:blood; D006716:Homosexuality; D006801:Humans; D008297:Male; D010641:Phenotype; D019896:alpha 1-Antitrypsin Deficiency