title: Clinical study of radioisotope clearance from the cerebrospinal fluid space using single photon emission computed tomography.
abstract: Radioisotope cisternography with statistical analysis was evaluated in 18 patients with suspected hydrocephalus shown by conventional CT, and 4 control patients. Regions of interest were located at cisterna magna, basal cistern, lateral cistern Sylvii, interhemispheric cistern, and lateral ventricle using three dimensional SPECT images. A value for the constant K was determined for each exponential radioactivity decay curve. On the basis of SPECT-derived K values our patients were grouped into hydrocephalus, nonhydrocephalus, and control patients. Twelve of 14 hydrocephalus patients were treated by shunt operation. Our less-invasive method showed reliable criteria for assessing the cerebrospinal fluid circulation.
authors: Department of Neurosurgery, Nagoya University School of Medicine, Japan.
authors: H
authors: H
authors: Kuchiwaki
authors: M
authors: M
authors: Nagasaka
authors: S
authors: S
authors: Takada
authors: H
authors: H
authors: Ishiguri
authors: H
authors: H
authors: Kameyama
authors: Y
authors: Y
authors: Aoyama
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002552:Cerebral Ventricles / Q000000981:diagnostic imaging; D002555:Cerebrospinal Fluid; D002946:Cisterna Magna / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000000981:diagnostic imaging* / Q000503:physiopathology; D007205:Indium Radioisotopes; D008297:Male; D008875:Middle Aged; D011851:Radioactivity; D011859:Radiography; D013997:Time Factors; D014055:Tomography, Emission-Computed
chemical_list: D007205:Indium Radioisotopes