SPECT perfusion imaging with 123I-HIPDM in a patient with pulmonary embolism.
The use of 123I-N,N,N'trimethyl-N'-2-hydroxy-3-methyl-5-iodobenzyl-1,3-propanediami ne (123I-HIPDM) as a lung perfusion tracer in a patient with pulmonary embolism is shown. 123I-HIPDM is compared with 99mTc-labeled human albumin microspheres (HAM) using both planar and tomographic (SPECT) imaging. Pulmonary segmental defects are shown by 123I-HIPDM as well as by HAM, with a slightly better definition of perfused areas. Tomograms better show segmental shape of perfusion defects. 123I-HIPDM may be proposed as lung perfusion tracer for both clinical and experimental purposes.
Petruzzelli
S
S
Palla
A
A
Prediletto
R
R
Mazzuca
N
N
Pistolesi
M
M
Giuntini
C
C
D006801:Humans; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging*; D014055:Tomography, Emission-Computed
D007457:Iodine Radioisotopes; D007462:Iodobenzenes; C036739:N,N,N'-trimethyl-N'-(2-hydroxy-3-methyl-5-iodobenzyl)-1,3-propanediamine