Processed Aloe vera administered topically inhibits inflammation.
Aloe vera preparations were evaluated for topical anti-inflammatory activity using the croton oil-induced edema assay. The results show that small amounts of A. vera given topically will inhibit inflammation induced by a moderate amount of irritant. In general, the decolorized Aloe was more effective than the colorized Aloe (with anthraquinone). A 47.1% inhibition of inflammation was obtained by 5% decolorized irradiated Aloe. These results may be used as a baseline to assess the biologic activity of A. vera in the treatment of inflammation by podiatric physicians.
Davis
R H
RH
Rosenthal
K Y
KY
Cesario
L R
LR
Rouw
G A
GA
D000287:Administration, Topical; D000504:Aloe / Q000528:radiation effects; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D003436:Croton Oil; D005069:Evaluation Studies as Topic; D005260:Female; D007249:Inflammation / Q000139:chemically induced / Q000188:drug therapy; D051379:Mice; D008813:Mice, Inbred ICR; D010936:Plant Extracts / Q000627:therapeutic use; D010946:Plants, Medicinal / Q000528:radiation effects
D000893:Anti-Inflammatory Agents; D010936:Plant Extracts; D003436:Croton Oil