title: [Changes in the phospholipid composition of mitochondria during heat incubation].
abstract: Incubation of liver mitochondria at 37 degrees C causes changes in the phospholipid composition, such as the decrease in the levels of major phospholipids (e.g. phosphatidylcholine, phosphatidylethanolamine, cardiolipin) and their lysoderivatives as well as an increase in the levels of phosphatidic and lysophosphatidic acids. Similar changes in the phospholipid composition are observed upon heat incubation of mitochondrial fragments ("ghosts", inner and outer mitochondrial membranes). Ca2+ accelerate the heat-induced changes in the phospholipid levels resulting from heat incubation, whereas EGTA, in contrast, decelerates them. The role of an endogenous system of lipolytic enzymes in the observed conversions of mitochondrial phospholipids is discussed.
authors: M M
authors: MM
authors: Rakhimov
authors: K T
authors: KT
authors: Almatov
authors: D T
authors: DT
authors: Mirtalipov
authors: O N
authors: ON
authors: Gorbataia
authors: G M
authors: GM
authors: Kasimova
mesh_terms: D000818:Animals; D006358:Hot Temperature; D008930:Mitochondria, Liver / Q000201:enzymology / Q000378:metabolism*; D010740:Phospholipases / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism*; D051381:Rats; D013379:Substrate Specificity
chemical_list: D010743:Phospholipids; D010740:Phospholipases
vernacular_title: Izmenenie fosfolipidnogo sostava mitokhondriĭ pri teplovoĭ inkubatsii.