[Determination of metronidazole in vehicles used externally by titration in a nonaqueous medium].
The analytical procedure has been elaborated for determination of metronidazole contents in the formulated preparation for external application in the form of a cream. Ambiphilic and emulsion bases were used as a vehicle. Water is removed from the preparation by drying/1 hour at 105 degrees C/and the amount of dry metronidazole residue is determined by titration in nonaqueous media with, 0.01 mol/l of perchloric acid.
Toskić-Radojicić
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Nidzović
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D002626:Chemistry, Pharmaceutical; D008795:Metronidazole / Q000008:administration & dosage / Q000032:analysis*; D009823:Ointment Bases / Q000032:analysis
D009823:Ointment Bases; D008795:Metronidazole
Odredivanje metronidazola u vehikulumu za spoljasnju upotrebu titracijom u nevodenoj sredini.