A model for the study of sex-linked influences through the study of different classes of cousin pairs.
Higher positive correlations in certain classes of cousin pairs compared with others would imply sex-linked genetic factors. Thus Y-linked influences would raise correlations in patrilateral male cousins. X-linkage would raise correlation (to various extents) in male and mixed sex pairs where each male is related through his mother, for instance. Among female first cousins, however, patrilateral pairs have the highest degree of kinship and cross cousins the lowest in respect to X-linked genes.
Lasker
G W
GW
Department of Anatomy and Cell Biology, Wayne state University of School of Medicine, Detroit, Michigan.
D005190:Family; D005260:Female; D005787:Gene Frequency; D008040:Genetic Linkage; D006801:Humans; D008297:Male; D008957:Models, Genetic; D014960:X Chromosome