title: GABAergic neurons in the primate basal forebrain magnocellular complex.
abstract: Hybridization histochemistry was used to detect messenger ribonucleic acid (mRNA) coding for glutamic acid decarboxylase, the synthesizing enzyme for gamma-aminobutyric acid (GABA), in neurons of the nucleus basalis of Meynert and nucleus of the diagonal band of Broca of one rhesus monkey and 4 baboons. GABAergic neurons were distributed among the unlabeled large, hyperchromic Nissl-stained neurons characteristic of this basal forebrain magnocellular complex, although they were infrequent within the dense islands of large cells. Most GABAergic cells were small to medium in size, but some were large and hyperchromic. These findings demonstrate a heterogeneous population of presumably inhibitory neurons in the basal forebrain magnocellular complex of primates.
authors: Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
authors: L C
authors: LC
authors: Walker
authors: D L
authors: DL
authors: Price
authors: W S
authors: WS
authors: Young
mesh_terms: D000818:Animals; D005260:Female; D005625:Frontal Lobe / Q000166:cytology / Q000378:metabolism*; D007150:Immunohistochemistry; D008253:Macaca mulatta; D008297:Male; D009693:Nucleic Acid Hybridization; D010215:Papio; D012333:RNA, Messenger / Q000378:metabolism*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
chemical_list: D012333:RNA, Messenger; D005680:gamma-Aminobutyric Acid