Mean residence time: some further considerations.
The correct use of probability distribution functions is described for the determination of mean residence time (MRT) of drug molecules in the body and is illustrated for two possible two compartment body models. A new method for estimating (MRT) is described, based on the area under the curve measurement for the decay of drug from steady state.
Collier
P S
PS
Department of Pharmacy, Queen's University of Belfast, Northern Ireland, U.K.
D006801:Humans; D007275:Injections, Intravenous; D008954:Models, Biological; D010599:Pharmacokinetics