[Inhibition of the adhesiveness and proliferation of gingival fibroblasts induced by short-chain fatty acids produced by anaerobic bacteria].
Short-chain fatty acids produced by anaerobic bacteria inhibit attachment and proliferation of gingival fibroblasts. Butyric acid, at concentration normally present in periodontal pockets, produced the highest degree of activity.
Eftimiadi
C
C
Tonetti
M
M
Zicca
A
A
Cadoni
A
A
Mangione
R
R
Gandolfo
A
A
Mangiante
P E
PE
D001421:Bacteria, Anaerobic / Q000378:metabolism*; D002087:Butyrates / Q000378:metabolism / Q000494:pharmacology; D002448:Cell Adhesion / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D005232:Fatty Acids, Volatile / Q000096:biosynthesis / Q000494:pharmacology*; D005347:Fibroblasts / Q000166:cytology / Q000187:drug effects*; D005881:Gingiva / Q000166:cytology* / Q000187:drug effects; D006131:Growth Inhibitors / Q000096:biosynthesis; D006801:Humans; D011422:Propionates / Q000378:metabolism / Q000494:pharmacology; D013386:Succinates / Q000378:metabolism / Q000494:pharmacology; D019802:Succinic Acid
D002087:Butyrates; D005232:Fatty Acids, Volatile; D006131:Growth Inhibitors; D011422:Propionates; D013386:Succinates; D019802:Succinic Acid
Inibizione dell'adesività e della proliferazione dei fibroblasti gengivali indotta dagli acidi grassi a catena corta prodotti dai batteri anaerobi.