Primary multilobulated B-cell lymphoma of the breast.
Malignant lymphomas with multilobulated nuclei are recently recognized neoplasms. We report a case of multilobulated B-cell lymphoma arising in the breast. The light microscopic, electron microscopic, and immunohistochemical features are described and compared with those of previously reported T- and B-cell multilobulated lymphomas from other sites. A follicular center cell origin of this lymphoma is postulated. To our knowledge, this is the first report of a primary multilobulated lymphoma of the breast.
Elavathil
L J
LJ
Department of Pathology, Women's College Hospital, Toronto, Ontario, Canada.
Kahn
H J
HJ
Hanna
W
W
D001402:B-Lymphocytes / Q000032:analysis / Q000473:pathology* / Q000648:ultrastructure; D001943:Breast Neoplasms / Q000032:analysis / Q000473:pathology* / Q000648:ultrastructure; D002467:Cell Nucleus / Q000473:pathology / Q000648:ultrastructure; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008228:Lymphoma, Non-Hodgkin / Q000032:analysis / Q000473:pathology* / Q000648:ultrastructure; D008875:Middle Aged