title: Histiocytosis X characterized by marked elevation of serum alkaline phosphatase and rapid destructive changes in the lung parenchyma.
abstract: A 23 yr old man was admitted suspected of having a liver disease because of marked elevation of the serum alkaline phosphatase. A biopsy of the liver was without cholestasis. A skin biopsy of a papule was compatible with eosinophilic granuloma. Over a few months the patient developed severe restrictive lung disease. The elevation of the serum alkaline phosphatase was probably due to diffuse bone affection.
authors: Dept. of Medicine 4, Kommunehospital, Copenhagen K, Denmark.
authors: P B
authors: PB
authors: Hansen
mesh_terms: D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood*; D006646:Histiocytosis, Langerhans-Cell / Q000097:blood / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D008171:Lung Diseases / Q000097:blood / Q000175:diagnosis / Q000473:pathology*; D008297:Male
chemical_list: D000469:Alkaline Phosphatase