title: Influence of menhaden oil on mitochondrial respiration in BHE rats.
abstract: The effects of corn or menhaden oil and thyroxine treatment on hepatic mitochondrial respiration was studied. BHE rats were fed a 64% sucrose, 6% corn, or menhaden oil diet until they were 60-70 days of age. Succinate-supported mitochondrial respiration was studied at 3 degrees C intervals from 4 to 40 degrees C. Upper and lower activation energies and transition temperatures were determined through the calculation of Arrhenius plot. Menhaden oil plus daily thyroxine injection resulted in higher and lower activation energies than the other treatments. This combined treatment also resulted in lower state 3 and higher state 4 respiration rates and tighter coupling of respiration to ATP synthesis. These effects were thought to be due to the effect this treatment combination had on membrane fluidity.
authors: Department of Foods and Nutrition, University of Georgia, Athens 30602.
authors: M J
authors: MJ
authors: Kim
authors: C D
authors: CD
authors: Berdanier
mesh_terms: D000818:Animals; D005395:Fish Oils / Q000494:pharmacology*; D007700:Kinetics; D008297:Male; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D010101:Oxygen Consumption / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values; D013386:Succinates / Q000378:metabolism; D013696:Temperature; D013974:Thyroxine / Q000097:blood / Q000494:pharmacology; D014284:Triiodothyronine / Q000097:blood
chemical_list: D005395:Fish Oils; D013386:Succinates; D014284:Triiodothyronine; C033266:Menhaden oil; D013974:Thyroxine