Comparative in vitro activities of ofloxacin, difloxacin, ciprofloxacin, and other selected antimicrobial agents against Brucella melitensis.
The in vitro activities of three quinolones (ofloxacin, difloxacin, and ciprofloxacin) were compared with those of trimethoprim-sulfamethoxazole, streptomycin, tetracycline, and rifampin against 47 Brucella melitensis strains. Ofloxacin was the most active of the test antimicrobial agents. It inhibited 90% of B. melitensis strains at a concentration of 0.02 micrograms/ml.
Khan
M Y
MY
King Fahad National Guard Hospital, Riyadh, Kingdom of Saudi Arabia.
Dizon
M
M
Kiel
F W
FW
D000890:Anti-Infective Agents / Q000494:pharmacology*; D002002:Brucella / Q000187:drug effects*; D002006:Brucellosis / Q000382:microbiology; D002939:Ciprofloxacin / Q000031:analogs & derivatives / Q000494:pharmacology; D024841:Fluoroquinolones; D006801:Humans; D008826:Microbial Sensitivity Tests; D015242:Ofloxacin / Q000494:pharmacology
D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D002939:Ciprofloxacin; C047225:difloxacin; D015242:Ofloxacin