Comparative efficacy of 12% ammonium lactate lotion and 5% lactic acid lotion in the treatment of moderate to severe xerosis.
This double-blind study was designed to evaluate treatment results and time effects of 12% ammonium lactate and 5% lactic acid lotion for moderate to severe xerosis. Results showed 12% ammonium lactate lotion was significantly more effective than 5% lactic acid lotion in reducing the severity of xerosis in both the 3-week, twice-a-day treatment period and the following 3-week, no-treatment (regression) period.
Rogers
R S
RS
Department of Dermatology, Mayo Clinic, Rochester, Minnesota.
Callen
J
J
Wehr
R
R
Krochmal
L
L
D000328:Adult; D000368:Aged; D004311:Double-Blind Method; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007057:Ichthyosis / Q000188:drug therapy*; D007773:Lactates / Q000627:therapeutic use*; D019344:Lactic Acid; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index
D007773:Lactates; D019344:Lactic Acid