title: Complete nucleotide sequence of the matrix protein mRNA of mumps virus.
abstract: The complete nucleotide sequence of the mumps virus membrane protein or matrix protein (M) has been determined by sequencing cDNA clones and confirmed by partially sequencing the M mRNA and the genome. The mRNA is 1248 nucleotides long excluding the poly(A) and encodes a protein of 375 amino acids. The molecular weight (38,670), deduced from the amino acid sequence, is in agreement with the molecular weight of the viral M protein estimated by polyacrylamide gel electrophoresis (39-40 kDa). The mumps virus M protein shows 23-27% homology with M proteins of Newcastle disease virus (NDV), measles virus, canine distemper virus (CDV), parainfluenza virus type 3, and Sendai virus, respectively. A comparison of the M protein sequences of the above six paramyxoviruses did not reveal any conserved area of homology common among all paramyxovirus M proteins.
authors: Department of Virology, School of Medicine, Karolinska Institute, Stockholm, Sweden.
authors: N
authors: N
authors: Elango
mesh_terms: D001483:Base Sequence; D004247:DNA; D008969:Molecular Sequence Data; D008970:Molecular Weight; D009109:Mumps virus / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics*; D012367:RNA, Viral / Q000235:genetics*; D014763:Viral Matrix Proteins / Q000235:genetics*
chemical_list: D012333:RNA, Messenger; D012367:RNA, Viral; D014763:Viral Matrix Proteins; D004247:DNA