Bleeding manifestations in megaloblastic anemia.
Ten children with megaloblastic anemia and a hemorrhagic diathesis are reported. Four of them had life-threatening bleeds necessitating an emergency blood transfusion. Seven had platelet counts of less than 30,000/cu mm, and nine had hemoglobin values of less than or equal to 5.2 g/dl at initial presentation. Deficiency of vitamin B12 was more frequently encountered. Response to therapy was excellent and hemostasis was possible within 12 to 24 hours of initiating treatment.
Marwaha
R K
RK
Singh
S
S
Garewal
G
G
Marwaha
N
N
Walia
B N
BN
Kumar
L
L
D000748:Anemia, Macrocytic; D000749:Anemia, Megaloblastic / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006474:Hemorrhagic Disorders / Q000150:complications*; D006801:Humans; D007194:India; D008297:Male; D011446:Prospective Studies; D014806:Vitamin B 12 Deficiency / Q000150:complications*