[The impact of antituberculosis drugs upon liver function in patients with positive HBVM].
Through the liver function analysis of 100 tuberculosis cases in the course of antituberculosis chemotherapy the authors found that the abnormal liver function rate turned to be 50% in the positive HBVM Group but only 2.4% in the negative, HBVM Group. There is a significant statistical difference between the two groups of cases (P less than 0.01). For this reason, the authors suggested the HBVM should be determined one by one before taking the antituberculosis chemotherapy in the area with high incidence of B-type hepatitis, the data indicated clearly that, the abnormal phenomena of liver function after the antituberculosis treatment for those patients, mainly caused by the drugs.
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D000328:Adult; D000995:Antitubercular Agents / Q000009:adverse effects*; D002353:Carrier State / Q000503:physiopathology*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology; D005260:Female; D006509:Hepatitis B / Q000503:physiopathology*; D006511:Hepatitis B Antigens / Q000032:analysis*; D006801:Humans; D008099:Liver / Q000187:drug effects*; D008111:Liver Function Tests; D008297:Male; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy* / Q000503:physiopathology
D000995:Antitubercular Agents; D006511:Hepatitis B Antigens