title: Use of midazolam--an alternative for controlled sedation.
abstract: Midazolam hydrochloride (midazolam) is a short-acting central nervous system depressant that allows controlled sedation of the patient after open-heart surgery. Use of an intravenous (IV) loading dose induces sleep rapidly, and can be supplemented by a titratable infusion to allow variations in the sleep-wake cycle. A loading dose of 0.1 mg/kg is given slowly IV. A continuous infusion with the dose based on mcg/kg calculation allows the nurse to titrate the infusion based on the desired therapeutic response.
authors: K
authors: K
authors: Gottlieb
authors: C
authors: C
authors: Birdsall
mesh_terms: D006348:Cardiac Surgical Procedures; D003422:Critical Care; D006801:Humans; D008874:Midazolam / Q000008:administration & dosage / Q000627:therapeutic use*; D009732:Nursing Care; D011182:Postoperative Care
chemical_list: D008874:Midazolam