title: Changes in noradrenaline and histamine in monkey spinal cords traumatised by weight drop, compression and subsequent decompression.
abstract: Levels of noradrenaline (NA) and histamine (H) in the spinal cord of monkeys at 8, 24 and 48 hr following 200 g/cm contusion injury, 50 g of compression injury at 8 hr and decompression for 16 and 40 hr following 8 hr of compression were studied in the traumatised and in an adjacent non-traumatised segment. The NA level doubled in the traumatised and non-traumatised segments at 8 hr contusion injury followed by a slow decline to control values at 24 and 48 hr of contusion injury. There was no change in NA content of the spinal cord segments at 8 hr of compression injury. Decompression for 16 hr following 8 hr of compression increased NA content of the traumatised segment. H levels decreased in the traumatised and non-traumatised segments at 24 and 48 hr of contusion injury. Compression for 8 hr elevated H in the traumatised and non-traumatised segments. On decompression H level was further increased in the traumatised segment.
authors: K
authors: K
authors: Panneerselvam
authors: L
authors: L
authors: Cherian
authors: A
authors: A
authors: Kuruvilla
authors: D R
authors: DR
authors: Theodore
authors: J
authors: J
authors: Abraham
mesh_terms: D000818:Animals; D005260:Female; D006632:Histamine / Q000378:metabolism*; D008255:Macaca radiata; D008297:Male; D009638:Norepinephrine / Q000378:metabolism*; D013117:Spinal Cord Compression / Q000378:metabolism*; D013119:Spinal Cord Injuries / Q000378:metabolism*
chemical_list: D006632:Histamine; D009638:Norepinephrine