[Subpopulations of peripheral blood T-lymphocytes in patients with chronic glomerulonephritis].
Patients with membranous proliferative glomerulonephritis in the presence of nephrotic syndrome of without it were investigated for subpopulation composition of T lymphocytes and their functional activity in pHA blast transformation test. Though no difference was revealed in E+- and Fc+-receptor occurrence, both spontaneous and PHA-induced malformation of autoreactive T cells were observed. The results justified the previous data on the deficiency in lymphopoiesis of undifferentiated cells with end deoxynucleotidyltransferase as a marker. In patients with nephrotic syndrome PHA-induced blast transformation test revealed a decrease in lymphocyte function.
Rakitianskaia
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IA
D002908:Chronic Disease; D015432:Glomerulonephritis, Membranoproliferative / Q000209:etiology / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D007958:Leukocyte Count; D008213:Lymphocyte Activation; D009404:Nephrotic Syndrome / Q000209:etiology / Q000276:immunology; D011961:Receptors, Fc / Q000032:analysis; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*
D011961:Receptors, Fc
Subpopuliatsii T-limfotsitov perifericheskoĭ krovi u bol'nykh khronicheskim glomerulonefritom.