title: Immunologic abnormalities associated with acute ischemic heart disease (a pilot study).
abstract: When in vivo and in vitro studies of patients with myocardial infarction (MI) were compared with healthy controls there was significantly diminished cutaneous cellular immunity and numbers of T lymphocytes in patients who suffered MI. This study contrasted patients with MI to controls and to patients with other types of cardiovascular disease. There was a significant difference when control patients were compared with those who failed to survive MI for 4 weeks (P less than .001). Patients who died in less than 1 month had 3.6 times less circulating percent T-cells than age-matched controls. A new method is described for categorization of in vitro T-cells in human subjects. If certain patients with low numbers of T-cells following MI die, perhaps this information may serve to alert the physician to intervene and correct the patient's course to recovery.
authors: Mount Zion Hospital and Medical Center, San Francisco, California.
authors: H S
authors: HS
authors: Kaufman
authors: V I
authors: VI
authors: Kvitash
mesh_terms: D000208:Acute Disease; D000787:Angina Pectoris / Q000401:mortality; D003327:Coronary Disease / Q000276:immunology*; D005500:Follow-Up Studies; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology; D009203:Myocardial Infarction / Q000401:mortality; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology