Detection of muscle necrosis in dermatomyositis by 111In-labelled antimyosin Fab fragments.
This paper presents the findings on two patients with a final diagnosis of dermatomyositis in whom 111In-antimyosin imaging revealed diffuse muscle necrosis of the limbs. The potential application of this scintigraphic procedure for diagnosis and follow-up of patients with dermatomyositis-polymyositis is addressed.
De Geeter
F
F
Department of Nuclear Medicine, University Hospital Vrije, Universiteit Brussels, Belgium.
Deleu
D
D
Debeuckelaere
S
S
De Coninck
A
A
Somers
G
G
Bossuyt
A
A
D000293:Adolescent; D000911:Antibodies, Monoclonal; D003882:Dermatomyositis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D005260:Female; D006801:Humans; D007140:Immunoglobulin Fab Fragments; D007205:Indium Radioisotopes; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000000981:diagnostic imaging* / Q000473:pathology; D009218:Myosins / Q000276:immunology*; D009336:Necrosis; D011877:Radionuclide Imaging; D014123:Toxoplasmosis / Q000150:complications
D000911:Antibodies, Monoclonal; D007140:Immunoglobulin Fab Fragments; D007205:Indium Radioisotopes; D009218:Myosins