[Atrophied gastritis and diet case-control study].
We carried out a case-control study to explore the relationship between atrophied gastritis and diet in Yantai District of Shandong Province where stomach cancer incidence is very high. The cases were diagnosed by histology from Jan. 1983 to Dec. 1986 in three hospitals of Qixia, Laiyang, and Zhaoyuan counties. The controls were selected from local rural population. The method of sampling was first to select two communities, then according to household registration to select at random controls with matched sex and age (a difference of less than one year as compared with cases). The total number of cases and that of controls was 62 cases and 186 controls, respectively. The data obtained by interviewers, who were trained before investigation, using a uniform questionnaire including diet history of 1965. The quantities of eight essential amino acids and vitamin B1, B2, C, and carotene were calculated from food intake. All continuous variables were changed into order variables, then conditional logistic regression models were used to estimate adjusted OR (odds ratio) and its 95% CI (confidence interval). The results showed that vitamin B1 exerted a protective effect for atrophied gastritis, and drinking alcohol was a risk factor. Carotene, vitamin C, and valine tended to be protective factors, but smoking and high tryptophane intake tended to be risk factors. However, all of them did not reach significant levels.
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D000328:Adult; D000368:Aged; D000428:Alcohol Drinking; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D004032:Diet; D005260:Female; D005756:Gastritis / Q000453:epidemiology*; D005757:Gastritis, Atrophic / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D012307:Risk Factors; D012494:Sampling Studies