Blood lipids as related to cardiovascular and neuroendocrine functions under different conditions in healthy males and females.
Correlations were calculated between, on the one hand, total serum cholesterol, low-density (LDL) and high-density (HDL) lipoprotein cholesterol, and triglycerides, and, on the other hand, systolic (SBP) and diastolic blood pressure (DBP), heart rate (HR), urinary epinephrine, norepinephrine, and cortisol in 30 healthy males and 30 healthy females, aged 30-50. The cardiovascular and neuroendocrine measurements were obtained under different real-life and laboratory conditions. The most striking finding was that, in men, but not in women, total serum cholesterol was significantly positively correlated with SBP in all conditions (LDL and HDL cholesterol followed the same pattern). In women, but not in men, epinephrine and norepinephrine during laboratory-induced mental stress were significantly positively correlated with total cholesterol, LDL and triglycerides.
Lundberg
U
U
Department of Psychiatry and Psychology, Karolinska Institutet, Stockholm, Sweden.
Fredrikson
M
M
Wallin
L
L
Melin
B
B
Frankenhaeuser
M
M
D000328:Adult; D000367:Age Factors; D001794:Blood Pressure; D004837:Epinephrine / Q000652:urine*; D005260:Female; D006339:Heart Rate; D006801:Humans; D006854:Hydrocortisone / Q000652:urine; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000652:urine*; D012737:Sex Factors; D013312:Stress, Physiological / Q000097:blood / Q000503:physiopathology* / Q000652:urine
D008055:Lipids; D006854:Hydrocortisone; D009638:Norepinephrine; D004837:Epinephrine