[Pharmaceutical and biopharmaceutical evaluation of acetylaminonitropropoxybenzolum (Falimint). 8. Biotransformation of the active agents].
Two metabolites of Falimint which have not been elucidated till now were demonstrated to be the glucuronides of 2-acetamino-4-nitro-phenol and 2-amino-4-nitro-phenol. A further metabolite was found by isolation with adsorption resins and identified to be the sulfuric acid conjugate of 2-amino-4-nitro-phenol.
Becher
M
M
Sektion Pharmazie, Martin-Luther-Universität Halle-Wittenberg.
Fürst
W
W
D000083:Acetanilides / Q000493:pharmacokinetics / Q000494:pharmacology*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000493:pharmacokinetics / Q000494:pharmacology*; D001711:Biotransformation; D006801:Humans
D000083:Acetanilides; D000894:Anti-Inflammatory Agents, Non-Steroidal; C031846:5'-nitro-2'-propoxyacetanilide
Zur pharmazeutischen und biopharmazeutischen Begutachtung von Acetylaminonitropropoxybenzolum (Falimint). 8. Mitteilung: Biotransformation des Wirkstoffes.