[Cell strains of A431 epidermoid carcinoma with altered epidermal growth factor reception].
Epidermal growth factor inhibits proliferation of A431 cells when added to the cultural medium. Strains of A431 cells, resistant to EGF (800 ng/ml), were obtained by one-step selection after the treatment of these cells by 1-methyl-3-nitro-1-nitrosoguanidine (MNNG). Two of the obtained strains differ from the initial line in the EGF reception.
Gudkova
D A
DA
Sorokin
A B
AB
D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000378:metabolism / Q000473:pathology*; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D003864:Depression, Chemical; D004305:Dose-Response Relationship, Drug; D004351:Drug Resistance; D004815:Epidermal Growth Factor / Q000378:metabolism / Q000494:pharmacology; D066246:ErbB Receptors / Q000187:drug effects / Q000378:metabolism*; D006801:Humans; D007457:Iodine Radioisotopes; D008769:Methylnitronitrosoguanidine / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D007457:Iodine Radioisotopes; D008769:Methylnitronitrosoguanidine; D004815:Epidermal Growth Factor; D066246:ErbB Receptors
Kletochnye shtammy épidermoidnoĭ kartsinomy A431 s izmenennoĭ retseptsieĭ épidermal'nogo faktora rosta.