[Acquisition of the sequence of a new subclass of human alpha- satellite DNA, localized in the centromere regions of two pairs of acrocentric chromosomes].
The results are presented in the paper on obtaining of a clone of sub-group of alpha-satellite human DNA localized in heterochromatin regions of two pairs of acrocentric chromosomes. The obtained repeated DNA sequence is represented in a genome by some 20,000 copies. Using of the blot-hybridization method made it possible to show the polymorphic restriction variant distribution being preserved in different individuals genomes. Intergenomic structural heterogeneity in this alpha-satellite DNA sub-group has been found only by using restriction endonuclease BamHI.
Gar'kavtsev
I V
IV
Tsvetkov
T G
TG
Shilova
N V
NV
Raevskaia
G V
GV
D001483:Base Sequence; D002503:Centromere; D002875:Chromosomes; D002877:Chromosomes, Human; D004276:DNA, Satellite / Q000235:genetics*; D006801:Humans; D009690:Nucleic Acid Conformation; D009693:Nucleic Acid Hybridization; D012091:Repetitive Sequences, Nucleic Acid; D015183:Restriction Mapping
D004276:DNA, Satellite
Poluchenie posledovatel'nosti novogo podklassa al'fa-satellitnoĭ DNK cheloveka, lokalizovannoĭ v tsentromernykh raĭonakh dvukh par akrotsentricheskikh khromosom.