title: Actions of bovine skin washings and sera on the motile zoospores of Dermatophilus congolensis.
abstract: Concentrated skin washings, even from vaccinated animals, failed to inhibit the motility of the infective zoospores of Dermatophilus congolensis, or to prevent them from germinating or infecting cattle; their constituent immunoglobulins did not attach to the flagella although IgA and IgG2 did bind to the cell bodies. It is concluded that the specific antibodies at the skin surface of ruminants are unlikely to have a role in zoospore immobilisation. Post vaccination sera rapidly immobilised and clumped the zoospores by means of a coat around the flagella, in which immunoglobulins, particularly IgM, were detected. IgM and IgG1 also attached to the cell bodies of the zoospores.
authors: Moredun Research Institute, Edinburgh.
authors: D M
authors: DM
authors: Jenkinson
authors: J D
authors: JD
authors: Menzies
authors: I A
authors: IA
authors: Pow
authors: L
authors: L
authors: Inglis
authors: D H
authors: DH
authors: Lloyd
authors: A
authors: A
authors: Mackie
mesh_terms: D000192:Actinomycetales / Q000276:immunology* / Q000648:ultrastructure; D000372:Agglutination Tests; D000818:Animals; D001428:Bacterial Vaccines / Q000276:immunology; D002417:Cattle; D002465:Cell Movement; D005407:Flagella / Q000276:immunology; D007106:Immune Sera / Q000276:immunology; D007070:Immunoglobulin A / Q000276:immunology; D007074:Immunoglobulin G / Q000276:immunology; D007075:Immunoglobulin M / Q000276:immunology; D007136:Immunoglobulins / Q000276:immunology*; D008297:Male; D008854:Microscopy, Electron; D012867:Skin / Q000276:immunology*; D014611:Vaccination / Q000662:veterinary
chemical_list: D001428:Bacterial Vaccines; D007106:Immune Sera; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins