title: The influence of personal activities on exposure to volatile organic compounds.
abstract: Seven persons volunteered to perform 25 common activities thought to increase personal exposure to volatile organic chemicals (VOCs) during a 3-day monitoring period. Personal, indoor, and outdoor air samples were collected on Tenax cartridges three times per day (evening, overnight, and daytime) and analyzed by GC-MS for 17 target VOCs. Samples of exhaled breath were also collected before and after each monitoring period. About 20 activities resulted in increasing exposure to one or more of the target VOCs, often by factors of 10, sometimes by factors of 100, compared to exposures during the sleep period. These concentrations were far above the highest observed outdoor concentrations during the length of the study. Breath levels were often significantly correlated with previous personal exposures. Major exposures were associated with use of deodorizers (p-dichlorobenzene); washing clothes and dishes (chloroform); visiting a dry cleaners (1,1,1-trichloroethane, tetrachloroethylene); smoking (benzene, styrene); cleaning a car engine (xylenes, ethylbenzene, tetrachloroethylene); painting and using paint remover (n-decane, n-undecane); and working in a scientific laboratory (many VOCs). Continuously elevated indoor air levels of p-dichlorobenzene, trichloroethylene, 1,1,1-trichloroethane, carbon tetrachloride, decane, and undecane were noted in several homes and attributed to unknown indoor sources. Measurements of exhaled breath suggested biological residence times in tissue of 12-18 hr and 20-30 hr for 1,1,1-trichloroethane and p-dichlorobenzene, respectively.
authors: U.S. Environmental Protection Agency, Washington, D.C. 20460.
authors: L A
authors: LA
authors: Wallace
authors: E D
authors: ED
authors: Pellizzari
authors: T D
authors: TD
authors: Hartwell
authors: V
authors: V
authors: Davis
authors: L C
authors: LC
authors: Michael
authors: R W
authors: RW
authors: Whitmore
mesh_terms: D000203:Activities of Daily Living; D000204:Activity Cycles / Q000187:drug effects; D000388:Air; D000473:Alkanes / Q000494:pharmacology; D001554:Benzene / Q000494:pharmacology; D001555:Benzene Derivatives / Q000494:pharmacology; D002722:Chlorobenzenes / Q000494:pharmacology; D002725:Chloroform / Q000494:pharmacology; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D007306:Insecticides / Q000494:pharmacology; D008297:Male; D013343:Styrenes / Q000494:pharmacology; D014240:Trichloroethanes / Q000494:pharmacology; D014992:Xylenes / Q000494:pharmacology
chemical_list: D000473:Alkanes; D001555:Benzene Derivatives; D002722:Chlorobenzenes; D007306:Insecticides; D013343:Styrenes; D014240:Trichloroethanes; D014992:Xylenes; C024566:1,1,1-trichloroethane; D002725:Chloroform; C018511:4-dichlorobenzene; D001554:Benzene; C004912:ethylbenzene; C012867:decane