title: [The role of disorders of components of the RASC system (regulation of the aggregation system of coagulation) in the pathogenesis of microangiopathies in vibration disease].
abstract: A complex assessment of the RASC system in patients with vibration disease of different stages of severity is presented. Early disorders of the thrombocytovascular chain of hemostasis have been established at the initial stage of the disease. When pathologic process grows worse, disorders of the coagulation chain are identified. Proceeding from the above studies it is shown that changes in the aggregate blood state are significant for microangiopathy pathogenesis in patients with vibration disease. Expediency of the use of antithrombocytic and vasoprotective preparations in complex treatment has been substantiated.
authors: A M
authors: AM
authors: Pakhomova
authors: T M
authors: TM
authors: Sukharevskaia
authors: M I
authors: MI
authors: Loseva
mesh_terms: D000328:Adult; D001777:Blood Coagulation; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000209:etiology*; D004738:Engineering; D006801:Humans; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D009784:Occupational Diseases / Q000097:blood / Q000209:etiology*; D010974:Platelet Aggregation; D014732:Vibration / Q000009:adverse effects*
vernacular_title: Ro'l narusheniia komponentov sistemy RASK v patogeneze mikro- angiopatii pri vibratsionnoĭ bolezni.