title: [Effects of clopheline on impulse activity of neurons in the midbrain and dorsal horn of the spinal cord].
abstract: Clophelin (1-5 mg/kg) suppresses spinal dorsal horn neuronal nociceptive responses but does not change their touch stimuli reactions in unanesthetized curarized cats. This effect is steady to naloxone (1 mg/kg), yohimbine (5 mg/kg) and removal by prazosin (1 mg/kg). Clophelin depresses nociceptive responses of the central gray matter neurones which generalized pain impulses in the supraspinal structures.
authors: A A
authors: AA
authors: Zaĭtsev
authors: S M
authors: SM
authors: Butkhuzi
authors: V V
authors: VV
authors: Kolchin
authors: B T
authors: BT
authors: Moroz
authors: Z A
authors: ZA
authors: Sakvarelidze
mesh_terms: D000818:Animals; D002415:Cats; D003000:Clonidine / Q000494:pharmacology*; D008636:Mesencephalon / Q000187:drug effects* / Q000503:physiopathology; D009270:Naloxone / Q000494:pharmacology; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D009619:Nociceptors / Q000187:drug effects*; D010146:Pain / Q000503:physiopathology; D011224:Prazosin / Q000494:pharmacology; D013116:Spinal Cord / Q000187:drug effects* / Q000503:physiopathology; D015016:Yohimbine / Q000494:pharmacology
chemical_list: D015016:Yohimbine; D009270:Naloxone; D003000:Clonidine; D011224:Prazosin
vernacular_title: Vliianie klofelina na impul'snuiu aktivnost' neĭronov srednego mozga i zadnego roga spinnogo mozga.