title: Pathology and general significance of fibrin deposition on lens implants.
abstract: The deposition of fibrin on the intraocular lens (IOL) in two cases of failed implantation is reported. In one case the network of fibrin fibers was isolated on the surface of an IOL that also showed a clear reactive protein film populated by macrophages and giant cells. In the other case the fibrin network was closely related to sessile macrophages on the implant surface. The presence of fibrin on IOLs indicates an acute phase of increased regional vascular permeability and is clinically important.
authors: Department of Ophthalmology, University of Michigan Medical Center, Ann Arbor 48105.
authors: J R
authors: JR
authors: Wolter
mesh_terms: D000368:Aged; D000867:Anterior Chamber / Q000276:immunology / Q000473:pathology; D002199:Capillary Permeability; D005260:Female; D005337:Fibrin / Q000096:biosynthesis*; D006801:Humans; D007910:Lenses, Intraocular / Q000009:adverse effects*; D008264:Macrophages / Q000276:immunology
chemical_list: D005337:Fibrin