[Energy metabolism in arteries and veins in modelling epinephrine damage to the vascular wall].
Experiments were conducted on rabbits to study some indices of energy metabolism in arteries and veins under conditions of chronic epinephrine intoxication. Reduced intensity of oxygen consumption, increased intensity of lactic acid production, and reduced content of macroergic phosphates (ATP, phosphocreatine) were revealed in the walls of the arteries studied. Disorders of energy metabolism in veins were either less marked (portal vein) or absent (vena cava posterior). The revealed decrease of the intensity of energy metabolism in the arterial wall is considered to be among the possible mechanisms of the development of Monckeberg's arteriosclerosis.
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D000818:Animals; D001158:Arteries / Q000187:drug effects / Q000378:metabolism*; D004734:Energy Metabolism; D004837:Epinephrine / Q000633:toxicity*; D005260:Female; D008297:Male; D008954:Models, Biological; D011817:Rabbits; D014680:Veins / Q000187:drug effects / Q000378:metabolism*
D004837:Epinephrine
Energeticheskiĭ obmen v arteriiakh i venakh v usloviiakh modelirovaniia adrenalinovykh porazheniĭ sosudistoĭ stenki.