Myxofibrosarcoma in the left atrium originally presented as a cardiac myxoma with chondroid differentiation. A clinico-pathological report.
Malignant cardiac tumours located on heart valves are very rare. We report on a myxofibrosarcoma originally presented as a cardiac myxoma (CM), partly with chondroid differentiation, located on the posterior leaflet of the mitral valve. The tumor recurred twice, the first time disguised as a CM with only minor components of myxofibrosarcoma, and finally metastazised as a myxofibrosarcoma. Patient survival (40 months from first surgery) was surprisingly long and this may well reflect both the effectiveness of the combined radiation and cytostatic treatment and the histopathological features of the tumor.
Johansson
L
L
Department of Pathology, University Hospital, Lund, Sweden.
Kugelberg
J
J
Thulin
L
L
D000328:Adult; D004452:Echocardiography; D006338:Heart Neoplasms / Q000175:diagnosis* / Q000473:pathology; D006349:Heart Valve Diseases / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D008943:Mitral Valve; D009232:Myxoma / Q000175:diagnosis* / Q000473:pathology; D009236:Myxosarcoma / Q000175:diagnosis* / Q000473:pathology; D012509:Sarcoma