Different karyotypic abnormalities, t(1;6) and del(7), in two uterine leiomyomas from the same patient.
Cytogenetic studies of two uterine leiomyomas from the same patient revealed different karyotypic changes. Both tumors showed only a single chromosome abnormality; one had t(1;6)(q23;p21) and the other del(7)(q21.2q31.2). These findings support the view that multiple leiomyomas of the uterus arise independently.
Nilbert
M
M
Department of Clinical Genetics, University Hospital, Lund, Sweden.
Heim
S
S
Mandahl
N
N
Flodérus
U M
UM
Willén
H
H
Mitelman
F
F
D002872:Chromosome Deletion; D002878:Chromosomes, Human, Pair 1; D002896:Chromosomes, Human, Pair 6; D002897:Chromosomes, Human, Pair 7; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D007889:Leiomyoma / Q000235:genetics* / Q000473:pathology; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic; D014594:Uterine Neoplasms / Q000235:genetics* / Q000473:pathology
D005819:Genetic Markers