[Immunomodulation mechanisms in the anti-tumor effect of the ECHO-7 enterovirus].
It has been established that the complex systemic and local administration of human ECHO-7 virus exerts an inhibitory effect on the growth of MX-17 tumour in the BALB/c mice without the signs of viral oncolysis. The antitumour effect is due to a modulation of the antitumour immunity (immunological regression) against a background of the viral immunogenesis.
Ferdat
A K
AK
Bruvere
R Zh
RZh
Vitolin'
L A
LA
Petrovska
R G
RG
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000818:Animals; D029822:Enterovirus B, Human / Q000276:immunology*; D008198:Lymph Nodes / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008748:Methylcholanthrene / Q000633:toxicity; D051379:Mice; D008807:Mice, Inbred BALB C; D012208:Rhabdomyosarcoma / Q000139:chemically induced / Q000628:therapy*; D013950:Thymus Gland / Q000276:immunology
D000276:Adjuvants, Immunologic; D008748:Methylcholanthrene
Mekhanizm immunomoduliatsii v protivoopukholevom deĭstvii énterovirusa ECHO-7.