Conservation of the putative receptor attachment site in picornaviruses.
A deep canyon or pit on the surfaces of human rhinovirus 14 and Mengo virus, respectively, has been proposed as a putative receptor binding site. Amino acids lining the surface of the canyon or pit have been identified and show greater conservation than other surface residues.
Rossmann
M G
MG
Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907.
Palmenberg
A C
AC
D000956:Antigens, Viral; D001665:Binding Sites; D003461:Crystallography; D008574:Mengovirus / Q000378:metabolism / Q000648:ultrastructure; D009500:Neutralization Tests; D010849:Picornaviridae / Q000378:metabolism* / Q000648:ultrastructure; D017955:Poliovirus / Q000378:metabolism / Q000648:ultrastructure; D011991:Receptors, Virus / Q000378:metabolism*; D012229:Rhinovirus / Q000378:metabolism / Q000648:ultrastructure; D013499:Surface Properties; D014961:X-Ray Diffraction
D000956:Antigens, Viral; D011991:Receptors, Virus