L-651,392: a novel, potent and selective 5-lipoxygenase inhibitor.
Guindon
Y
Y
Department of Medicinal Chemistry and Pharmacology, Merck Frosst Canada Inc., Pointe Claire-Dorval, Quebec.
Girard
Y
Y
Maycock
A
A
Ford-Hutchinson
A W
AW
Atkinson
J G
JG
Bélanger
P C
PC
Dallob
A
A
DeSousa
D
D
Dougherty
H
H
Egan
R
R
D000818:Animals; D001091:Arachidonate Lipoxygenases / Q000037:antagonists & inhibitors*; D001980:Bronchi / Q000187:drug effects; D002199:Capillary Permeability / Q000187:drug effects; D006801:Humans; D066298:In Vitro Techniques; D007975:Leukotriene B4 / Q000096:biosynthesis; D016859:Lipoxygenase Inhibitors; D010640:Phenothiazines / Q000494:pharmacology*; D013189:SRS-A / Q000096:biosynthesis
D016859:Lipoxygenase Inhibitors; D010640:Phenothiazines; D013189:SRS-A; D007975:Leukotriene B4; C053726:4-bromo-2,7-dimethoxy-3H-phenothiazin-3-one; D001091:Arachidonate Lipoxygenases