title: Growth hormone receptor and serum binding protein: purification, cloning and expression.
abstract: A putative growth hormone receptor from rabbit liver and the growth hormone binding protein from rabbit serum have the same amino-terminal amino-acid sequence, indicating that the binding protein corresponds to the extracellular hormone-binding domain of the liver receptor. The complete amino-acid sequences derived from complementary DNA clones encoding the putative human and rabbit growth hormone receptors are not similar to other known proteins, demonstrating a new class of transmembrane receptors.
authors.affiliation: Department of Developmental Biology, Genentech, Inc., South San Francisco, California.
authors.forename: D W
authors.initials: DW
authors.lastname: Leung
authors.forename: S A
authors.initials: SA
authors.lastname: Spencer
authors.forename: G
authors.initials: G
authors.lastname: Cachianes
authors.forename: R G
authors.initials: RG
authors.lastname: Hammonds
authors.forename: C
authors.initials: C
authors.lastname: Collins
authors.forename: W J
authors.initials: WJ
authors.lastname: Henzel
authors.forename: R
authors.initials: R
authors.lastname: Barnard
authors.forename: M J
authors.initials: MJ
authors.lastname: Waters
authors.forename: W I
authors.initials: WI
authors.lastname: Wood
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002352:Carrier Proteins / Q000235:genetics* / Q000302:isolation & purification; D003001:Cloning, Molecular; D004247:DNA / Q000302:isolation & purification / Q000378:metabolism; D004262:DNA Restriction Enzymes; D013006:Growth Hormone / Q000097:blood*; D008099:Liver / Q000378:metabolism; D008969:Molecular Sequence Data; D011817:Rabbits; D011986:Receptors, Somatotropin / Q000235:genetics* / Q000302:isolation & purification; D014158:Transcription, Genetic
chemical_list: D002352:Carrier Proteins; D011986:Receptors, Somatotropin; D013006:Growth Hormone; D004247:DNA; D004262:DNA Restriction Enzymes; C051815:somatotropin-binding protein