A ouabain-displacing factor in normal pregnancy, pregnancy-induced hypertension and pre-eclampsia.
1. A ouabain-displacing factor (ODF) was measured in the urine of non-pregnant, normotensive pregnant and hypertensive pregnant women by a receptor-binding assay with sodium, potassium-dependent adenosine triphosphatase. 2. Urinary ODF was significantly increased in normal pregnancy. 3. Greater increases were seen in pregnancy-induced hypertension and pre-eclampsia.
Gregoire
I
I
Service de Néphrologie, CHU, Amiens, France.
Roth
D
D
Siegenthaler
G
G
Fievet
P
P
el Esper
N
N
Favre
H
H
Fournier
A
A
D000328:Adult; D000450:Aldosterone / Q000097:blood; D002298:Cardenolides; D002395:Catecholamines / Q000097:blood; D004077:Digoxin; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000652:urine*; D045283:Natriuretic Agents / Q000652:urine*; D010953:Plasma Volume; D011225:Pre-Eclampsia / Q000097:blood / Q000652:urine*; D011247:Pregnancy / Q000097:blood / Q000652:urine*; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood / Q000652:urine*; D012083:Renin / Q000097:blood; D012503:Saponins; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors* / Q000652:urine; D014527:Uric Acid / Q000097:blood
D002298:Cardenolides; D002395:Catecholamines; D045283:Natriuretic Agents; D012503:Saponins; C034504:digoxin-like factors; D014527:Uric Acid; D000450:Aldosterone; D004077:Digoxin; D012083:Renin; D000254:Sodium-Potassium-Exchanging ATPase