Restriction endonuclease resistant chromatin in human chromosomes.
The recent addition of restriction endonucleases in obtaining selective bands in the human genome has added a new dimension to molecular genetics. However, a considerable discrepancy exists in banding patterns produced by AluI in chromosomes 19 and 20, by MboI in chromosomes 4, 5, 8, 21 and 22 and by RsaI in chromosomes 12, 21 and 22. The principal causes of these differences are highlighted.
Babu
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Division of Genetics, Beth Israel Medical Center, New York, New York.
Verma
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D000653:Amniotic Fluid / Q000166:cytology; D002843:Chromatin / Q000648:ultrastructure*; D002871:Chromosome Banding; D002877:Chromosomes, Human; D004262:DNA Restriction Enzymes; D006801:Humans; D007621:Karyotyping; D008214:Lymphocytes / Q000166:cytology / Q000276:immunology
D002843:Chromatin; D004262:DNA Restriction Enzymes