Improved survival after brain metastases in non-seminomatous germ cell tumours with combined modality treatment.
Long-term disease-free survival (78 + and 31 + months) has been achieved in two of four patients treated for brain metastases from non-seminomatous germ cell tumours between 1980 and 1984. The incidence of cerebral metastases among 101 patients seen over the 5-year period was 4%. The encouraging results from the use of combined modality treatment, incorporating cisplatin-based chemotherapy, whole brain irradiation and surgery, are reviewed.
Raghavan
D
D
Urological Cancer Research Unit, Royal Prince Alfred Hospital, Camperdown, Australia.
Mackintosh
J F
JF
Fox
R M
RM
Rogers
J
J
Duval
P
P
Besser
M
M
D000328:Adult; D001932:Brain Neoplasms / Q000401:mortality / Q000556:secondary* / Q000628:therapy; D002945:Cisplatin / Q000627:therapeutic use; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000401:mortality / Q000556:secondary* / Q000628:therapy; D013736:Testicular Neoplasms / Q000401:mortality
D002945:Cisplatin