Transcriptional autoregulation of the proto-oncogene fos.
Serum-induced transcription of the proto-oncogene fos is under negative feedback regulation mediated by the fos protein. The fos promoter region responsive to repression is also required for serum inducibility and binds a nucleoprotein complex in which the nuclear factor AP-1 is associated with fos protein.
Sassone-Corsi
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P
Molecular Biology and Virology Laboratory, Salk Institute, San Diego, California 92138.
Sisson
J C
JC
Verma
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D000818:Animals; D001483:Base Sequence; D001769:Blood; D004262:DNA Restriction Enzymes / Q000378:metabolism; D006360:Heat-Shock Proteins / Q000235:genetics; D006801:Humans; D051379:Mice; D008969:Molecular Sequence Data; D011401:Promoter Regions, Genetic; D000090063:Proto-Oncogene Mas; D011519:Proto-Oncogenes; D014158:Transcription, Genetic
D006360:Heat-Shock Proteins; C000715470:MAS1 protein, human; D000090063:Proto-Oncogene Mas; D004262:DNA Restriction Enzymes