The non-specific stimulation of avian peripheral blood lymphocytes from uninfected chickens by paramyxoviruses and influenza viruses.
Avian paramyxovirus-3 was mitogenic to peripheral blood lymphocytes (PBL) from about half the normal birds sampled from 3 inbred flocks. Eight other myxoviruses including Newcastle disease virus, Sendai virus and influenza virus were also irregularly mitogenic. This could complicate in vitro assays for specific immunity.
Russell
P H
PH
Department of Microbiology and Parasitology, Royal Veterinary College, University of London, Gt. Britain.
D000818:Animals; D002478:Cells, Cultured; D002645:Chickens / Q000097:blood* / Q000276:immunology; D009980:Influenza A virus / Q000276:immunology*; D008213:Lymphocyte Activation; D008934:Mitogens / Q000494:pharmacology; D009522:Newcastle disease virus / Q000276:immunology; D010047:Ovalbumin / Q000276:immunology; D010222:Parainfluenza Virus 1, Human / Q000276:immunology; D010252:Paramyxoviridae / Q000276:immunology*; D012710:Serum Albumin, Bovine / Q000276:immunology; D013047:Specific Pathogen-Free Organisms
D008934:Mitogens; D012710:Serum Albumin, Bovine; D010047:Ovalbumin