title: [Morphological changes in experimental amyotrophic leukospongiosis].
abstract: A new nosological entity of slow infections provoked by noncanonical viruses was experimentally studied. It was shown that natural human infection and infection induced in guinea pigs had common clinical and morphological parameters and were characterized by severe changes in the central nervous system. Histologically, the death of the motoneurones of the spinal cord, the spongious state of the white matter of the brain and spinal cord, relative preservation of myelin, hypertrophy and proliferation of macroglia were histologically observed.
authors.forename: G P
authors.initials: GP
authors.lastname: Duboĭskaia
authors.forename: N D
authors.initials: ND
authors.lastname: Kolomiets
authors.forename: S A
authors.initials: SA
authors.lastname: Guzov
authors.forename: S A
authors.initials: SA
authors.lastname: Luchko
authors.forename: A G
authors.initials: AG
authors.lastname: Kolomiets
mesh_terms: D000818:Animals; D001927:Brain Diseases / Q000209:etiology / Q000473:pathology*; D004195:Disease Models, Animal; D005260:Female; D006168:Guinea Pigs; D008297:Male; D009474:Neurons / Q000473:pathology; D012897:Slow Virus Diseases / Q000473:pathology* / Q000635:transmission; D013116:Spinal Cord / Q000473:pathology
vernacular_title: Morfologicheskie izmeneniia pri éksperimental'nom amiotroficheskom leĭkospongioze.