title: Ultrastructural findings on human Scarpa's ganglion.
abstract: The morphology of human Scarpa's ganglion from two surgically removed specimens as well as from four autopsy preparations from patients without clinical evidence of vestibular dysfunction was investigated. Ganglion cell circumference varied between 45 and 160 microns. More than half of the nerve cells ranged between 90 and 110 microns. The arrangement of ganglion cells, nerve fibres and endoneural connective tissue appeared better preserved in autopsy preparation than in biopsy specimens. Electron microscopy revealed that in half of the investigated specimens, neuroglial tissue was present as far distal as the vestibular ganglion. Almost all ganglion cells were surrounded by one or several layers of satellite cells, and did not reveal myelination. From the present study we cannot predict if neuronal function in human beings differs from that in other animals, although morphological differences do exist.
authors.affiliation: ENT Department, University Hospital, Zürich, Switzerland.
authors.forename: H
authors.initials: H
authors.lastname: Felix
authors.forename: V
authors.initials: V
authors.lastname: Hoffmann
authors.forename: A
authors.initials: A
authors.lastname: Wright
authors.forename: M
authors.initials: M
authors.lastname: Gleeson
mesh_terms: D000328:Adult; D000368:Aged; D006801:Humans; D008875:Middle Aged; D009186:Myelin Sheath / Q000502:physiology; D009457:Neuroglia / Q000648:ultrastructure; D009435:Synaptic Transmission; D014725:Vestibular Nerve / Q000166:cytology / Q000648:ultrastructure*