title: Lateral differences in GABA binding sites in rat brain.
abstract: An asymmetric distribution of GABA binding sites was found in the cerebral cortex, hippocampus, cerebellar hemispheres, striatum, and thalamus. Higher levels of [3H]GABA binding were observed in the left-side of most brain areas and in a greater percentage of adult rats, but the opposite asymmetry was found in the thalamus. A similar left-right difference in cerebral hemispheres was also found in five day-old rats, suggesting the genetic predetermination of asymmetry.
authors.affiliation: Institute of Neuropsychiatry, University of Palermo, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Guarneri
authors.forename: R
authors.initials: R
authors.lastname: Guarneri
authors.forename: V
authors.initials: V
authors.lastname: La Bella
authors.forename: S
authors.initials: S
authors.lastname: Scondotto
authors.forename: F
authors.initials: F
authors.lastname: Scoppa
authors.forename: F
authors.initials: F
authors.lastname: Piccoli
mesh_terms: D000818:Animals; D001665:Binding Sites; D001921:Brain / Q000378:metabolism* / Q000502:physiology; D002540:Cerebral Cortex / Q000032:analysis / Q000502:physiology; D003342:Corpus Striatum / Q000032:analysis / Q000502:physiology; D007839:Functional Laterality / Q000502:physiology*; D006624:Hippocampus / Q000032:analysis / Q000502:physiology; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D011963:Receptors, GABA-A / Q000032:analysis*
chemical_list: D011963:Receptors, GABA-A