title: [Morphology of experimental malignant fibrous histiocytoma].
abstract: The microscopic structure of tumors induced in rats by subcutaneous injections of 7,12-dimethylbenz(a) anthracene (DMBA) was studied. Most of them (90%) were histologically identical to malignant fibrous histiocytoma (MFH) in humans. This experimental model is useful in MFH morphogenesis and histogenesis studies in connection with the high frequency and synchronicity of tumor development and distinct localization of tumor at the site of injection.
authors.forename: K M
authors.initials: KM
authors.lastname: Pozharisskiĭ
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Nikitin
mesh_terms: D015127:9,10-Dimethyl-1,2-benzanthracene; D000818:Animals; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000139:chemically induced / Q000473:pathology*; D008297:Male; D051381:Rats
chemical_list: D015127:9,10-Dimethyl-1,2-benzanthracene
vernacular_title: Morfologiia éksperimental'noĭ zlokachestvennoĭ fibroznoĭ gistiotsitomy.