title: Metabolic diversions in the oxidative metabolism of hepatic and neuronal systems of rat (Wistar strain) under induced benthiocarb stress.
abstract: Metabolic diversions in oxidative metabolism of hepatic and neuronal systems of rat were noticed during induced benthiocarb stress. The inhibition of dehydrogenases indicates disturbed mitochondrial integrity, and reduction in cytochrome-C-oxidase suggests possible respiratory distress. The drop in ATPases and PNPPase indicates the prevalence of energy crisis. The increased specific activities of NADP+ dependent dehydrogenases suggests augmented lipid biosynthesis in the wake of impaired oxidative metabolism.
authors.affiliation: Department of Zoology, Sri Venkateswara University, Tirupati, India.
authors.forename: G R
authors.initials: GR
authors.lastname: Babu
authors.forename: G R
authors.initials: GR
authors.lastname: Reddy
authors.forename: P N
authors.initials: PN
authors.lastname: Srinivas
authors.forename: C S
authors.initials: CS
authors.lastname: Chetty
mesh_terms: D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000201:enzymology; D007306:Insecticides / Q000633:toxicity*; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008297:Male; D010088:Oxidoreductases / Q000037:antagonists & inhibitors*; D051381:Rats; D011919:Rats, Inbred Strains; D013312:Stress, Physiological / Q000201:enzymology; D013859:Thiocarbamates
chemical_list: D007306:Insecticides; D013859:Thiocarbamates; C037925:benthiocarb; D010088:Oxidoreductases