title: [Hyperthermia in bone and soft tissue tumors].
abstract: Local response of hyperthermia for soft tissue and bone tumors was investigated. Ten tumors were superficial tumors and 16 were deep seated tumors; 9 tumors were malignant fibrous histiocytoma, 5 were liposarcoma, 4 were neurogenic and 3 were myogenic sarcoma. The other five tumors were an angiosarcoma, a malignant mesenchymoma, an Ewing's sarcoma, a chordoma and an osteosarcoma. Some 23 tumors were heated in combination with radiation therapy, and 3 were combined with arterial infusion of ADR. Four of 10 superficial tumors disappeared (CR), and, 2 of 10 signified PR. Only one of 16 deep seated tumors showed CR, 3 were PR and 12 showed no response. But 4 of 12 tumors without regression in tumor volume indicated coagulation necrosis owing to histological examinations, and 5 of 12 were regarded as the same response from hypodensity area with CT examination after hyperthermia. Local response rate of of superficial tumors was 60% and that of deep-seated tumors was 81.4%.
authors.affiliation: Dept. of Radiation Therapy, National Cancer Center.
authors.forename: Y
authors.initials: Y
authors.lastname: Kajiura
authors.forename: I
authors.initials: I
authors.lastname: Tsukiyama
authors.forename: T
authors.initials: T
authors.lastname: Ogino
authors.forename: Y
authors.initials: Y
authors.lastname: Akine
authors.forename: S
authors.initials: S
authors.lastname: Egawa
mesh_terms: D001859:Bone Neoplasms / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000628:therapy; D006801:Humans; D006979:Hyperthermia, Induced; D007261:Infusions, Intra-Arterial; D008297:Male; D011846:Radio Waves; D011882:Radiotherapy, High-Energy; D012509:Sarcoma / Q000628:therapy; D012983:Soft Tissue Neoplasms / Q000473:pathology / Q000628:therapy*
chemical_list: D004317:Doxorubicin