Establishment of cytotoxic T-cell clones specific for cells infected with mouse hepatitis virus.
Mouse hepatitis virus (MHV)-specific T-lymphocyte clones were established from MHV-infected BALB/c mice. They expressed Thy1 and Lyt2 antigens but lacked L3T4 and NK1 antigens. The clones killed MHV-infected but not uninfected or influenza virus-infected J774.1 cells. The specificity was further defined by a cold-target competition test.
Yamaguchi
K
K
Department of Animal Pathology, University of Tokyo, Japan.
Kyuwa
S
S
Nakanaga
K
K
Hayami
M
M
D000818:Animals; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis; D002999:Clone Cells / Q000276:immunology; D003601:Cytotoxicity Tests, Immunologic; D051379:Mice; D008807:Mice, Inbred BALB C / Q000276:immunology; D006517:Murine hepatitis virus / Q000276:immunology*; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*
D000945:Antigens, Differentiation, T-Lymphocyte