[Effect of drugs on superoxide formation by neutrophilic granulocytes].
The in-vitro influence of drugs on the superoxide production of human neutrophils was investigated. The superoxide production is inhibited by colchicine, g-strophanthin, propranolol, fluphenazine and stimulated by levamisole and lithium. The superoxide production is inhibited or stimulated by chloramphenicol, hydrocortisone and amphotericin B in concentration dependent manner.
Schmidt
D
D
Institut für Medizinische Mikrobiologie, Medizinischen Akademie Magdeburg.
Morenz
E
E
Morenz
J
J
D000666:Amphotericin B / Q000494:pharmacology; D002701:Chloramphenicol / Q000494:pharmacology; D003078:Colchicine / Q000494:pharmacology; D005476:Fluphenazine / Q000494:pharmacology; D006801:Humans; D006854:Hydrocortisone / Q000494:pharmacology; D007978:Levamisole / Q000494:pharmacology; D008094:Lithium / Q000494:pharmacology; D016651:Lithium Carbonate; D009504:Neutrophils / Q000187:drug effects*; D010042:Ouabain / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D013481:Superoxides / Q000378:metabolism*
D013481:Superoxides; D007978:Levamisole; D016651:Lithium Carbonate; D010042:Ouabain; D002701:Chloramphenicol; D000666:Amphotericin B; D008094:Lithium; D011433:Propranolol; D005476:Fluphenazine; D003078:Colchicine; D006854:Hydrocortisone
Einfluss von Arzneimitteln auf die Superoxidbildung der neutrophilen Granulozyten.