Metabolic diversions in the oxidative metabolism of hepatic and neuronal systems of rat (Wistar strain) under induced benthiocarb stress.
Metabolic diversions in oxidative metabolism of hepatic and neuronal systems of rat were noticed during induced benthiocarb stress. The inhibition of dehydrogenases indicates disturbed mitochondrial integrity, and reduction in cytochrome-C-oxidase suggests possible respiratory distress. The drop in ATPases and PNPPase indicates the prevalence of energy crisis. The increased specific activities of NADP+ dependent dehydrogenases suggests augmented lipid biosynthesis in the wake of impaired oxidative metabolism.
Babu
G R
GR
Department of Zoology, Sri Venkateswara University, Tirupati, India.
Reddy
G R
GR
Srinivas
P N
PN
Chetty
C S
CS
D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000201:enzymology; D007306:Insecticides / Q000633:toxicity*; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008297:Male; D010088:Oxidoreductases / Q000037:antagonists & inhibitors*; D051381:Rats; D011919:Rats, Inbred Strains; D013312:Stress, Physiological / Q000201:enzymology; D013859:Thiocarbamates
D007306:Insecticides; D013859:Thiocarbamates; C037925:benthiocarb; D010088:Oxidoreductases