title: The importance of using anterior and posterior views in the calculation of differential renal function using 99Tcm-DMSA.
abstract: Radionuclide techniques for determining relative renal function are well established. One simple method uses the count rate from static images obtained using 99Tcm-dimercaptosuccinic acid (DMSA). We have reviewed 277 DMSA scans and shown that it is important to obtain the geometric mean of counts from the anterior and posterior views in order to correct for the different amounts of attenuation for each kidney. If counts were obtained from the posterior view only, erroneous results would be obtained in 8% of children under 13 years, in 28% of patients aged between 13 and 20 years and in 32% of patients over 20 years of age.
authors.affiliation: Department of Nuclear Medicine, Manchester Royal Infirmary.
authors.forename: R
authors.initials: R
authors.lastname: Wujanto
authors.forename: R S
authors.initials: RS
authors.lastname: Lawson
authors.forename: M C
authors.initials: MC
authors.lastname: Prescott
authors.forename: H J
authors.initials: HJ
authors.lastname: Testa
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging* / Q000503:physiopathology; D007677:Kidney Function Tests / Q000379:methods; D008297:Male; D009942:Organometallic Compounds; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D004113:Succimer; D013438:Sulfhydryl Compounds; D019783:Technetium Tc 99m Dimercaptosuccinic Acid
chemical_list: D009942:Organometallic Compounds; D013438:Sulfhydryl Compounds; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D004113:Succimer