[Recurrence of Wilm's tumor following a 9-year disease-free interval].
We report the case of a 25-year old female patient, who presented with intrapulmonary metastases of a Wilms' tumor nine and a half year after initial therapy of a stage I tumor with surgery, local radiation and combined chemotherapy. In general, relapses of Wilms' tumor occur within two year after nephrectomy. Recurrences after more than 7 years are very rare. A relapse of a Wilms' tumor in an adult patient after more than 9 years is not yet published. We treated our patient according to the therapeutic procedure, which is recommended by the National Wilms' Tumor Study as curative treatment of relapses in childhood: complete resection of pulmonary metastases, irradiation of the whole lunge and repeatingly combined chemotherapy with actinomycin D and vincristin. The patient is doing well without evidence of tumor 13 months after thoractomy. A short review of the literature is given.
Göldel
N
N
III. Medizinische Klinik, Universität München.
Jehn
U
U
Naujokat
B
B
Permanetter
W
W
D000293:Adolescent; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007668:Kidney / Q000473:pathology; D007680:Kidney Neoplasms / Q000473:pathology* / Q000628:therapy; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary*; D009367:Neoplasm Staging; D009392:Nephrectomy; D009396:Wilms Tumor / Q000473:pathology / Q000556:secondary* / Q000628:therapy
Rezidiv eines Wilms' Tumors nach 9jährigem krankheitsfreien Intervall.