Acquired myeloperoxidase deficiency of neutrophils in a patient with aplastic anemia (idiopathic marrow aplasia).
A case of aplastic anemia is described, in which bacterial and fungal infections were coincidental with a sudden development of an almost complete myeloperoxidase deficiency of neutrophils. The discrepancy on the differential white cell count between the logic and oscilloscopic finding of the autoanalyzer (Technicon H6000) and the results of the microscopic examination of the slides allowed a correct diagnosis of the enzymatic anomaly.
Bizzaro
N
N
Istituto di Patologia Clinica, Ospedale Civile, Venice, Italy.
Briani
G
G
Boccato
P
P
D000741:Anemia, Aplastic / Q000097:blood / Q000150:complications / Q000201:enzymology*; D001424:Bacterial Infections / Q000097:blood / Q000201:enzymology / Q000209:etiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009503:Neutropenia / Q000097:blood / Q000201:enzymology / Q000209:etiology; D009504:Neutrophils / Q000201:enzymology*; D009195:Peroxidase / Q000172:deficiency*
D009195:Peroxidase