Environmental pleural plaques in residents of a Quebec chrysotile mining town.
We report four cases of pleural plaques found at autopsy in individuals who resided in or near the chrysotile mining town of Thetford Mines, Quebec, and who had never been employed in the chrysotile mining and milling industry. Three of these patients were farmers, and one was a road construction worker. Lung asbestos content of these cases was compared with that of a group of nine persons living in the same vicinity who did not have pleural plaques. The plaque group was found to have an equal chrysotile content but about a fourfold elevation in median tremolite content, a statistically significant increase. Fiber sizes were the same in both groups. Also, one plaque case had an elevated level of relatively long titanium oxide fibers. These observations suggest that environmental pleural plaques in this region of Quebec are probably caused by exposure to tremolite derived from local soil and rock and that other types of mineral fibers such as titanium oxide may occasionally also be the cause of such lesions.
Churg
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Department of Pathology and Health Sciences, Centre Hospital, University of British Columbia, Vancouver, Canada.
DePaoli
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D000368:Aged; D001194:Asbestos / Q000009:adverse effects* / Q000032:analysis; D017636:Asbestos, Amphibole; D017632:Asbestos, Serpentine; D001195:Asbestosis / Q000209:etiology*; D004787:Environmental Pollution / Q000009:adverse effects*; D006801:Humans; D008168:Lung / Q000032:analysis; D008297:Male; D008906:Mining; D010995:Pleural Diseases / Q000209:etiology*; D011792:Quebec; D012824:Silicic Acid / Q000009:adverse effects* / Q000032:analysis; D012822:Silicon Dioxide / Q000009:adverse effects*; D014025:Titanium / Q000032:analysis
D017636:Asbestos, Amphibole; D017632:Asbestos, Serpentine; D001194:Asbestos; D012824:Silicic Acid; C005846:tremolite; D012822:Silicon Dioxide; D014025:Titanium