Inactivation of human and simian rotaviruses by ozone.
The inactivation of simian rotavirus SA-11 and human rotavirus type 2 (Wa) by ozone was compared at 4 degrees C by using single-particle virus stocks. Although the human strain was clearly more sensitive, both virus types were rapidly inactivated by ozone concentrations of 0.25 mg/liter or greater at all pH levels tested. Comparison of the virucidal activity of ozone with that of chlorine in identical experiments indicated little significant difference in rotavirus-inactivating efficiencies when the disinfectants were used at concentrations of 0.25 mg/liter or greater.
Vaughn
J M
JM
Department of Applied Science, Brookhaven National Laboratory, Upton, New York 11973.
Chen
Y S
YS
Lindburg
K
K
Morales
D
D
D000818:Animals; D002713:Chlorine / Q000494:pharmacology; D004203:Disinfection; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010126:Ozone / Q000494:pharmacology*; D012401:Rotavirus / Q000187:drug effects*; D012984:Software; D013242:Sterilization
D002713:Chlorine; D010126:Ozone