title: Recent insertion of an Alu sequence in the beta-globin gene cluster of the gorilla.
abstract: We present the nucleotide sequence of a new Alu family member that lies between the delta- and beta-globin genes in gorilla DNA. The sequence exhibits 91% similarity with a consensus sequence of the Alu family. It is flanked by a perfect repetition of a 16-nucleotide target sequence and terminates with 24 adenylic residues. As this sequence is absent at this locus in other primate DNAs, its insertion occurred less than 8 million years ago, thus supporting the idea that Alu sequences are still mobile elements in the hominoid genome.
authors.affiliation: Département de Biologie Générale et Appliquée Claude Bernard-Lyon, Villeurbanne, France.
authors.forename: G
authors.initials: G
authors.lastname: Trabuchet
authors.forename: Y
authors.initials: Y
authors.lastname: Chebloune
authors.forename: P
authors.initials: P
authors.lastname: Savatier
authors.forename: J
authors.initials: J
authors.lastname: Lachuer
authors.forename: C
authors.initials: C
authors.lastname: Faure
authors.forename: G
authors.initials: G
authors.lastname: Verdier
authors.forename: V M
authors.initials: VM
authors.lastname: Nigon
mesh_terms: D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D004262:DNA Restriction Enzymes; D004251:DNA Transposable Elements; D005796:Genes; D005914:Globins / Q000235:genetics*; D006071:Gorilla gorilla / Q000235:genetics*; D008969:Molecular Sequence Data
chemical_list: D004251:DNA Transposable Elements; D005914:Globins; D004262:DNA Restriction Enzymes