[Effects of somatotropic hormone on Na, K-ATPase of the synaptosomal membrane of the young rat brain].
Human somatotropic hormone (STH), starting from a concentration of 5.10(38) M, was found to inactivate in vitro (by 37%) the Na, K-ATPase activity of osmotically disrupted synaptosomes from 3-week-old rat brain. The inhibitory effect of STH was stronger with higher concentrations. The synaptosomal Mg- and Ca-ATPase activities were stimulated by STH (5.10(-9)-5.10(-6) M). Only at a concentration of 5.10(-6) M STH did inactivate the synaptosomal Na, K-ATPase from the adult rat brain.
Shkolovoĭ
V V
VV
Kryzhanovskiĭ
G N
GN
Glebov
R N
RN
D000367:Age Factors; D000818:Animals; D001921:Brain / Q000201:enzymology*; D013006:Growth Hormone / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D007425:Intracellular Membranes / Q000201:enzymology; D008297:Male; D051381:Rats; D000254:Sodium-Potassium-Exchanging ATPase / Q000032:analysis*; D013574:Synaptosomes / Q000201:enzymology*
D013006:Growth Hormone; D000254:Sodium-Potassium-Exchanging ATPase
Vliianie somatotropnogo gormona na Na, K-ATFazu membran sinaptosom mozga krysiat.