[Effect of cadmium chloride on the processes of learning and memory in rats].
Intraperitoneal injection of cadmium chloride (4 mg/kg) to rats before elaboration or reproduction of two-way avoidance conditioned reflex (TACR) disturbs both these processes. Deterioration of elaboration does not affect connections fixation and their subsequent reproduction. Injection of the substance before the elaboration of passive avoidance conditioned reflex (PACR) depresses elaboration and consolidation. Injection of cadmium chloride before testing of PACR preservation does not influence the processes of engrams reproduction. The observed disturbances cannot be connected with changes of animals motor activity.
Nurmukhambetov
A N
AN
Iksymbaeva
Zh S
ZhS
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects*; D002104:Cadmium / Q000494:pharmacology*; D019256:Cadmium Chloride; D003214:Conditioning, Classical / Q000187:drug effects; D004558:Electric Stimulation; D008297:Male; D008568:Memory / Q000187:drug effects*; D009043:Motor Activity / Q000187:drug effects; D010775:Photic Stimulation; D051381:Rats; D013997:Time Factors
D002104:Cadmium; D019256:Cadmium Chloride
Vliianie khloristogo kadmiia na protsessy obucheniia i pamiati u krys.