The third type of alpha-subunit of Na,K-ATPase.
The cDNA encoding the third type of alpha-subunit of NaK-ATPase was found in rat brain cDNA library. The deduced amino acid sequence was very similar to those of alpha- and alpha plus-subunits. The third one was suggested to be highly ouabain-sensitive from its aminoacid sequence. From Northern blot analysis the third type of the subunit was not expressed in adult rat kidney and heart.
Hara
Y
Y
Dept of Biochemistry, Tokyo Medical and Dental University, Japan.
Urayama
O
O
Kawakami
K
K
Nojima
H
H
Nagamune
H
H
Kojima
T
T
Ohta
T
T
Nagano
K
K
Nakao
M
M
D000818:Animals; D001921:Brain / Q000201:enzymology*; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D046911:Macromolecular Substances; D000254:Sodium-Potassium-Exchanging ATPase / Q000235:genetics* / Q000378:metabolism; D013045:Species Specificity
D046911:Macromolecular Substances; D004247:DNA; D000254:Sodium-Potassium-Exchanging ATPase