Marek's disease. XVII. Studies on virus induced-atherosclerosis.
Marek's disease herpesvirus (MDV) specific internal antigens were found in arterial segments of Single Comb White Leghorn, the Cornell strain, and of broiler chickens infected with virulent type 1 Mh-87 strain of MDV. Atherosclerosis was reproducibly induced in specific pathogen free (SPF) and in broiler chickens by infection with Mh-87 strain of MDV. Under these conditions a direct association was established between MDV infection and MDV-induced-atherosclerosis.
Pătraşcu
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IV
Stefan S. Nicolau Institute of Virology, Bucharest, Romania.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D001158:Arteries / Q000473:pathology; D001161:Arteriosclerosis / Q000209:etiology / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D002645:Chickens; D004198:Disease Susceptibility; D008381:Herpesvirus 2, Gallid / Q000276:immunology; D008380:Marek Disease / Q000150:complications* / Q000276:immunology / Q000473:pathology; D009131:Muscle, Smooth, Vascular / Q000276:immunology; D013047:Specific Pathogen-Free Organisms
D000956:Antigens, Viral