[Malignant endocrine tumor of the pancreas and ensuing clinical syndromes].
We report the observation of an endocrine tumor of the pancreas with metastasis to the liver which was apparently non-secreting. The evolution after resection by distal pancreatectomy was remarkable for the successive occurrence of a Zollinger-Ellison syndrome which was resistant to a gastric resection, then a hyperglycemia coma with ketoacidosis and finally a glucagonoma syndrome. This observation is the basis of a discussion on the multisecretory aspect of endocrine tumors of the pancreas.
Boumghar
M
M
Centre Hospitalier Universitaire Vaudois (CHUV), Service de Chirurgie A, Lausanne, Suisse.
D007516:Adenoma, Islet Cell / Q000150:complications* / Q000473:pathology / Q000601:surgery; D003926:Diabetic Coma / Q000209:etiology*; D005260:Female; D005935:Glucagonoma / Q000150:complications; D006801:Humans; D007340:Insulinoma / Q000150:complications; D008113:Liver Neoplasms / Q000556:secondary; D008875:Middle Aged; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D003969:Vipoma / Q000150:complications; D015043:Zollinger-Ellison Syndrome / Q000209:etiology* / Q000601:surgery
Tumeur endocrine maligne du pancréas et syndromes cliniques successifs.