title: Molecular epidemiology of OHIO-1 beta-lactamase.
abstract: A total of 31 plasmids, all bearing a gene that encodes a novel, plasmid-mediated Richmond-Sykes class III beta-lactamase designated OHIO-1 and a gene that encodes aminoglycoside 2"-adenyltransferase, have been collected from hospitals in Ohio. By using restriction endonuclease digestion and Southern hybridization, we were able to demonstrate that all these plasmids have a common genetic origin.
authors.affiliation: Infectious Diseases Section, Cleveland Veterans Administration Medical Center, Ohio.
authors.forename: M A
authors.initials: MA
authors.lastname: Kron
authors.forename: D M
authors.initials: DM
authors.lastname: Shlaes
authors.forename: C
authors.initials: C
authors.lastname: Currie-McCumber
authors.forename: A A
authors.initials: AA
authors.lastname: Medeiros
mesh_terms: D001419:Bacteria / Q000201:enzymology / Q000235:genetics*; D004262:DNA Restriction Enzymes; D004269:DNA, Bacterial / Q000235:genetics; D009693:Nucleic Acid Hybridization; D010957:Plasmids; D001618:beta-Lactamases / Q000032:analysis*
chemical_list: D004269:DNA, Bacterial; D004262:DNA Restriction Enzymes; D001618:beta-Lactamases