The structure and evolution of the spider monkey delta-globin gene.
We have isolated the delta-globin gene of the New-World spider monkey, Ateles geoffroyi, and compared its nucleotide sequence with those of other primate delta- and beta-globin genes. Among primate delta-globin genes, the rate of nonsynonymous substitutions is much less than the rate of synonymous substitutions. This suggests that primate delta-globin genes may remain under evolutionary conservation, perhaps because hemoglobin A2 has an as yet unknown physiological importance.
Spritz
R A
RA
Department of Medical Genetics and Pediatrics, University of Wisconsin--Madison 53706.
Giebel
L B
LB
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D002427:Cebidae / Q000235:genetics*; D003001:Cloning, Molecular; D004262:DNA Restriction Enzymes; D005914:Globins / Q000235:genetics*; D000882:Haplorhini / Q000235:genetics; D006801:Humans; D046911:Macromolecular Substances; D008297:Male; D008969:Molecular Sequence Data; D009710:Nucleotide Mapping; D010215:Papio / Q000235:genetics; D012867:Skin / Q000378:metabolism; D013045:Species Specificity
D046911:Macromolecular Substances; D005914:Globins; D004262:DNA Restriction Enzymes