Monoclonal antibodies with neutralizing activity segregate isolates of bovine viral diarrhea virus into groups. Brief report.
Isolates of bovine viral diarrhea (BVD) virus were differentiated by monoclonal antibodies (MoAbs) reactive with the 56 kD viral polypeptide. Patterns of neutralizing activity of the MoAbs indicate that multiple epitopes are involved in virus neutralization.
Bolin
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Virology Cattle Research Unit, National Animal Disease Center, USDA, Ames, Iowa.
Moennig
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Kelso Gourley
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Ridpath
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D000911:Antibodies, Monoclonal / Q000276:immunology*; D000914:Antibodies, Viral / Q000276:immunology; D000956:Antigens, Viral / Q000276:immunology*; D003588:Cytopathogenic Effect, Viral; D001908:Diarrhea Viruses, Bovine Viral / Q000145:classification* / Q000276:immunology; D008562:Membrane Glycoproteins / Q000276:immunology; D008970:Molecular Weight; D009500:Neutralization Tests; D010576:Pestivirus / Q000145:classification*; D014764:Viral Proteins / Q000276:immunology*
D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D000956:Antigens, Viral; D008562:Membrane Glycoproteins; D014764:Viral Proteins