Regional lipiodolized chemotherapy for cholangiocarcinoma associated with oral contraceptives.
We describe a case of cholangiocarcinoma in a young woman, who presented with cholestatic jaundice following oral contraceptive ingestion. Following diagnostic laparotomy she received intra-arterial 'lipiodolized' chemotherapy. Intravenous mitozantrone was given for 2 years and she is asymptomatic, with computed tomographic evidence of tumour response, 27 months after diagnosis. We suggest that this form of treatment is of value for cholangiocarcinoma.
McAleer
J J
JJ
Royal Victoria Hospital, Belfast, UK.
Dickey
W
W
Clarke
R
R
Johnston
G W
GW
Callender
M E
ME
D002759:Adenoma, Bile Duct / Q000139:chemically induced / Q000188:drug therapy*; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003138:Common Bile Duct Neoplasms / Q000139:chemically induced / Q000188:drug therapy*; D003277:Contraceptives, Oral, Combined / Q000009:adverse effects*; D003973:Diatrizoate / Q000008:administration & dosage; D003974:Diatrizoate Meglumine / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007269:Injections, Intra-Arterial; D007459:Iodized Oil / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000139:chemically induced / Q000188:drug therapy*; D008942:Mitoxantrone / Q000627:therapeutic use
D003277:Contraceptives, Oral, Combined; D003973:Diatrizoate; D003974:Diatrizoate Meglumine; D007459:Iodized Oil; D004317:Doxorubicin; D008942:Mitoxantrone