A formate based precursor for the preparation of technetium complexes.
Tc-formate complexes have been prepared by electrolytic, stannous, and borohydride reduction of pertechnetate in formate buffer. Individual Tc-formate complexes were isolated from reaction mixtures with silica bonded phase anion-exchange HPLC. The predominate air stable red Tc-formate complex has a negative charge, an absorption maximum at 536 nm, and a molecular weight between 100 and 300 dalton. The isolated major Tc-formate complex was found to react with isocyanide, diphosphonate, and various nitrogenous ligands. The relevant use of Tc-formate complexes as synthetic precursors to other technetium complexes is seen as being beneficial to the understanding of technetium ligand substitution.
Kennedy
C M
CM
Department of Chemistry, Purdue University, West Lafayette, IN 47907.
Mikelsons
M V
MV
Lawson
B L
BL
Pinkerton
T C
TC
D055598:Chemical Phenomena; D002621:Chemistry; D005561:Formates; D008024:Ligands; D013667:Technetium
D005561:Formates; D008024:Ligands; D013667:Technetium