Retinal oxalosis. A clinicopathologic report.
A 55-year-old woman with chronic renal failure treated with hemodialysis had severe bilateral visual loss develop due to retinal ischemia. Ophthalmoscopy showed crystals in the distribution of the retinal arteries, but not veins, and this led to a diagnosis of systemic oxalosis. Factors contributing to systemic oxalosis in addition to renal failure were ascorbic acid dietary supplementation, pyridoxine deficiency, and ileal resection. Histopathologic findings showed ocular calcium oxalate deposition limited nearly entirely to the walls of retinal blood vessels.
Wells
C G
CG
Department of Ophthalmology, University of Washington, School of Medicine, Seattle.
Johnson
R J
RJ
Qingli
L
L
Bunt-Milam
A H
AH
Kalina
R E
RE
D000328:Adult; D001205:Ascorbic Acid / Q000009:adverse effects; D001718:Birefringence; D002129:Calcium Oxalate / Q000032:analysis / Q000378:metabolism; D003460:Crystallization; D005123:Eye / Q000473:pathology / Q000648:ultrastructure; D005451:Fluorescein Angiography; D006084:Graft Rejection; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy; D016030:Kidney Transplantation; D008875:Middle Aged; D006435:Renal Dialysis; D012164:Retinal Diseases / Q000209:etiology* / Q000378:metabolism / Q000473:pathology
D002129:Calcium Oxalate; D001205:Ascorbic Acid