title: [Oxygen free radicals and bronchial asthma].
abstract: Oxygen free radicals are released generally by many cells during phagocytosis and cell activation. In asthmatics, some experimental evidence indicates that oxygen free radicals may be considered to be chemical mediators of anaphylaxis. They are released by macrophages, eosinophils and neutrophils, the cells that are found in bronchoalveolar lavage. They may explain some pathological changes, such as hardening of the airways, bronchial hyper-reactivity and inflammation. Therapeutic implications are discussed.
authors.affiliation: Clinique des Maladies Respiratoires, Hôpital Aiguelongue, CHRU, Montpellier.
authors.forename: P
authors.initials: P
authors.lastname: Godard
authors.forename: M
authors.initials: M
authors.lastname: Damon
authors.forename: M
authors.initials: M
authors.lastname: Cluzel
authors.forename: J
authors.initials: J
authors.lastname: Bousquet
authors.forename: P
authors.initials: P
authors.lastname: Chanez
authors.forename: A
authors.initials: A
authors.lastname: Crastes De Paulet
authors.forename: F B
authors.initials: FB
authors.lastname: Michel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001249:Asthma / Q000378:metabolism*; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology; D005609:Free Radicals; D006801:Humans; D008264:Macrophages / Q000378:metabolism*; D008875:Middle Aged; D010100:Oxygen / Q000378:metabolism*; D013481:Superoxides / Q000378:metabolism
chemical_list: D005609:Free Radicals; D013481:Superoxides; D010100:Oxygen
vernacular_title: Radicaux libres de l'oxygène et asthme bronchique.