title: Subclinical Aujeszky's disease virus infection in a pig herd and the characterisation of the strain of virus isolated.
abstract: The spread of antibody to Aujeszky's disease virus through a susceptible pig herd was monitored after the probable introduction of infection by a recently purchased boar. The infection spread slowly through the herd but no clinical signs of Aujeszky's disease were seen. The strain of virus isolated was designated NIA-6. It has been characterised by a series of experimental infections and extends the known range of virulence of isolates of Aujeszky's disease virus made in Northern Ireland. The strain caused no disease in four-week-old piglets and is therefore less virulent than other isolates from Northern Ireland pigs. However, it killed rabbits and a proportion of experimentally infected two-week-old piglets, which differentiates it from the avirulent bovine isolate (NIA-4).
authors.affiliation: Veterinary Research Laboratories, Stormont, Belfast.
authors.forename: S J
authors.initials: SJ
authors.lastname: McCullough
authors.forename: D
authors.initials: D
authors.lastname: Todd
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D000956:Antigens, Viral / Q000032:analysis; D001921:Brain / Q000382:microbiology; D004279:DNA, Viral / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005455:Fluorescent Antibody Technique; D011558:Herpesvirus 1, Suid / Q000235:genetics / Q000276:immunology / Q000472:pathogenicity*; D008297:Male; D009305:Nasopharynx / Q000382:microbiology; D009500:Neutralization Tests; D011557:Pseudorabies / Q000276:immunology / Q000382:microbiology*; D011817:Rabbits; D013552:Swine; D013553:Swine Diseases / Q000276:immunology / Q000382:microbiology*; D014774:Virulence
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral; D004279:DNA, Viral