title: The determination of relative kidney function in obstructive uropathy with 99Tcm-DMSA.
abstract: In this investigation differential kidney function studies were carried out for eight patients with obstructive uropathy and seven patients who did not suffer from obstruction. The aim of this investigation was to determine whether possible retention of 99Tcm-DMSA in the dilated system would lead to overestimation of the functional mass of an obstructed kidney. The clinical examination took place 4 and 24 h after i.v. injection of the 99Tcm-DMSA. From our results we conclude that this is not a major problem. It appeared that the 4 h values are as reliable as the 24 h values in the clinical situation.
authors.affiliation: Department of Diagnostic Radiology (Division of Nuclear Medicine), University Hospital Leiden, The Netherlands.
authors.forename: E K
authors.initials: EK
authors.lastname: Pauwels
authors.forename: A A
authors.initials: AA
authors.lastname: Lycklama à Nijeholt
authors.forename: J W
authors.initials: JW
authors.lastname: Arndt
authors.forename: U
authors.initials: U
authors.lastname: Jonas
mesh_terms: D006801:Humans; D007674:Kidney Diseases / Q000000981:diagnostic imaging / Q000378:metabolism / Q000503:physiopathology*; D009942:Organometallic Compounds / Q000493:pharmacokinetics*; D011877:Radionuclide Imaging; D004113:Succimer / Q000493:pharmacokinetics*; D013438:Sulfhydryl Compounds / Q000493:pharmacokinetics*; D013667:Technetium; D019783:Technetium Tc 99m Dimercaptosuccinic Acid
chemical_list: D009942:Organometallic Compounds; D013438:Sulfhydryl Compounds; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D013667:Technetium; D004113:Succimer