title: Breast cancer in a patient with silicone breast implants after 13 years.
abstract: The patient described in this article is a 45-year-old woman who developed an infiltrating ductal carcinoma in her left breast next to a Silastic mammary implant that had been used for augmentation some 13 years previously. She underwent a modified radical mastectomy and removal of the silicone prosthesis with an axillary lymph node dissection. Twenty-six axillary lymph nodes were negative for metastatic disease. The 165-gram silicone gel prosthesis was surrounded by a thin fibrous capsule with an attached 1-cm carcinoma that did not invade the fibrous capsule. It appeared that the capsule presented a barrier to the invading ductal carcinoma. The fibrous capsule surrounding the Silastic implant may have altered the spread of the breast cancer without being related to its genesis.
authors.affiliation: Division of Plastic and Reconstructive Surgery, University of Florida Medical Center, Gainesville 32610.
authors.forename: H G
authors.initials: HG
authors.lastname: Bingham
authors.forename: E M
authors.initials: EM
authors.lastname: Copeland
authors.forename: R
authors.initials: R
authors.lastname: Hackett
authors.forename: H H
authors.initials: HH
authors.lastname: Caffee
mesh_terms: D001940:Breast / Q000601:surgery*; D001943:Breast Neoplasms / Q000473:pathology*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D019736:Prostheses and Implants / Q000009:adverse effects*; D012826:Silicone Elastomers
chemical_list: D012826:Silicone Elastomers