title: A neurochemical approach to the study of sleep.
abstract: Sleep deprivation and recovery induce, in the hypothalamic preoptic region of the rat, opposite changes in cyclic AMP concentration which, when plotted in the standard form of the normal distribution, define two significantly divergent distributions. Thus, these opposite functional conditions may be related to corresponding changes in a biochemical parameter within an area involved in the control of the sleeping-waking cycle.
authors.affiliation: Institute of Human Physiology, University of Bologna, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Zamboni
authors.forename: R
authors.initials: R
authors.lastname: Amici
authors.forename: E
authors.initials: E
authors.lastname: Perez
mesh_terms: D000818:Animals; D002940:Circadian Rhythm; D000242:Cyclic AMP / Q000378:metabolism*; D009994:Osmolar Concentration; D010296:Parietal Lobe / Q000378:metabolism; D011301:Preoptic Area / Q000378:metabolism*; D012890:Sleep / Q000502:physiology*; D012892:Sleep Deprivation / Q000502:physiology
chemical_list: D000242:Cyclic AMP