Feline panleucopenia--in vivo infectivity studies.
Feline panleucopenia virus was separated into "full" and "empty" particles by banding in caesium chloride ultracentrifugation. Field cats free of serum neutralising antibodies were separately infected with "full", "empty" and "mixed" particles of the virus. No clinical disease was produced. However, cats infected with "full" particles developed antibody more rapidly than cats infected with the other particles.
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School of Tropical Veterinary Science, James Cook University, Townsville, Qld., Australia.
D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis; D002415:Cats; D002499:Centrifugation, Density Gradient; D005254:Feline Panleukopenia / Q000276:immunology / Q000382:microbiology*; D028301:Feline Panleukopenia Virus / Q000276:immunology / Q000472:pathogenicity*; D006385:Hemagglutination Inhibition Tests; D006386:Hemagglutination Tests; D010321:Parvoviridae / Q000472:pathogenicity*; D014461:Ultracentrifugation
D000914:Antibodies, Viral