Acute myeloblastic leukemia with extensive erythrophagocytosis mimicking malignant histiocytosis.
The authors report a case of acute myeloblastic leukemia in which erythrophagocytosis by the leukemic cells was so extensive as to mimic malignant histiocytosis at postmortem. It is postulated that premature expression of phagocytic function in leukemic cells and disseminated intravascular coagulopathy, which accompanied the initial clinical presentation, explained the unusually prominent erythrophagocytosis.
Hassinger
S L
SL
Department of Pathology, University of Maryland School of Medicine, Baltimore.
Schiffer
C A
CA
Sun
C C
CC
D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D004912:Erythrocytes; D005260:Female; D054747:Histiocytic Sarcoma / Q000503:physiopathology*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000473:pathology / Q000503:physiopathology*; D008099:Liver / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D010587:Phagocytosis; D013154:Spleen / Q000473:pathology