Human papillomavirus type 2 DNA in oral and labial verruca vulgaris.
Twenty instances of verruca vulgaris, equally divided between oral mucosa and lip vermillion, were assayed for the presence of human papillomavirus (HPV) capsid antigen and type-specific DNA employing in situ hybridization methods. All 10 cases arising on lip vermillon expressed capsid antigen and harbored HPV Type 2 genomes as assessed under conditions of high stringency DNA hybridization. Oral verrucae rarely expressed capsid antigen; HPV Type 2 genomes were encountered in 20% of the cases.
Eversole
L R
LR
Department of Oral Diagnostic Sciences, University of Florida, Gainesville 32610.
Laipis
P J
PJ
Green
T L
TL
D000956:Antigens, Viral / Q000032:analysis; D004279:DNA, Viral / Q000032:analysis; D006801:Humans; D008047:Lip Diseases / Q000382:microbiology* / Q000473:pathology; D009059:Mouth Diseases / Q000382:microbiology* / Q000473:pathology; D009693:Nucleic Acid Hybridization; D027383:Papillomaviridae / Q000276:immunology / Q000302:isolation & purification*; D014412:Tumor Virus Infections / Q000382:microbiology*; D014860:Warts / Q000382:microbiology* / Q000473:pathology
D000956:Antigens, Viral; D004279:DNA, Viral