A new approach for EPR detection of hydroxyl radicals by reaction with sterically hindered cyclic amines and oxygen.
Sterically hindered cyclic amines react with hydroxyl radicals in the presence of oxygen to yield stable nitroxide radicals which can be detected by EPR. This reaction provides a nonconventional spin-trapping tool for detection of hydroxyl radicals.
Rosenthal
I
I
Division of Contaminant Chemistry, Center for Food Safety and Applied Nutrition, Washington, DC 20204.
Krishna
C M
CM
Yang
G C
GC
Kondo
T
T
Riesz
P
P
D000588:Amines; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods; D005609:Free Radicals; D006878:Hydroxides / Q000032:analysis*; D017665:Hydroxyl Radical; D013113:Spin Labels
D000588:Amines; D005609:Free Radicals; D006878:Hydroxides; D013113:Spin Labels; D017665:Hydroxyl Radical