[The status of the monooxygenase enzyme system of the liver in Salmonella infection in rats].
Content and activity of microsomal cytochromes P450 and b5, amidopyrine N-demethylase, aniline hydroxylase, NADPH cytochrome c reductase were studied in liver tissue of rats with salmonelliasis. Distinct inhibition of the liver monooxygenase enzymatic system was detected during the acute period of the disease; its normalization was complete within the reconvalescence period. Endotoxinemia appears to be mainly responsible for alterations in the microsomal enzymes activity observed.
Krakovskiĭ
M E
ME
Ashirmetov
A Kh
AKh
Musabaev
E I
EI
Alieva
L G
LG
D000818:Animals; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology*; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D051381:Rats; D012481:Salmonella Infections, Animal / Q000201:enzymology*
D006899:Mixed Function Oxygenases
Sostoianie monooksigenaznoĭ fermentnoĭ sistemy pecheni pri sal'monelleznoĭ infektsii u krys.