The prognostic value of EEG patterns in epilepsies with infantile spasms.
By scoring EEG patterns (hypsarrhythmia = 10, absence of sleeping patterns = 10, focal epileptic discharge = 5, general-treatment or in whom infantile spasms never disappeared even during ACTH. A low voltage EEG did not have any ending ACTH therapy free of seizures showed lower scores compared to those infants relapsing after the end of ACTH treatment or in whom infantile spasms never disappeared even during ACTH. A low voltage EED did not have any prognostic significance. Using EEG scores it might be possible to separate non-responders and responders after 3 weeks of ACTH therapy, thus shortening ACTH treatment in non-responding infants.
Rating
D
D
Department of Pediatrics, Free University of Berlin, GFR.
Seidel
U
U
Grimm
B
B
Hanefeld
F
F
D000324:Adrenocorticotropic Hormone / Q000627:therapeutic use; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies; D013036:Spasms, Infantile / Q000188:drug therapy / Q000503:physiopathology*
D000324:Adrenocorticotropic Hormone