title: [Functional indices of the hypophysis, gonads and adrenal cortex during the treatment of patients with gonorrheal inflammation of the scrotal organs using proteolytic enzymes].
abstract: Chymotrypsin, a proteolytic enzyme included in combined therapy of 27 patients with gonorrhea complicated by the scrotal organs inflammation, has normalized the functions of the hypophyseo-gonadal and hypophyseo-adrenal systems, i.e. hypophyseal luteotropic function, adrenocortical gluco- and mineralocorticoid functions, and testicular androgenopoiesis. Hyperprolactin- and hyperprogesteronemia persisted after therapy, hyperestrogenism and follitropic hypofunction of the hypophysis have developed, that may become the reason of stable pathospermia and disordered fertility after therapy of complicated gonorrhea.
authors.forename: L G
authors.initials: LG
authors.lastname: Barabanov
mesh_terms: D000302:Adrenal Cortex / Q000187:drug effects / Q000503:physiopathology*; D002918:Chymotrypsin / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004823:Epididymitis / Q000188:drug therapy / Q000503:physiopathology*; D006069:Gonorrhea / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D008297:Male; D009920:Orchitis / Q000188:drug therapy / Q000503:physiopathology*; D010902:Pituitary Gland / Q000187:drug effects / Q000503:physiopathology*; D013094:Spermatozoa / Q000187:drug effects; D013737:Testis / Q000187:drug effects / Q000503:physiopathology*; D013997:Time Factors
chemical_list: D002918:Chymotrypsin
vernacular_title: Pokazateli funktsii gipofiza, polovykh zhelez i kory nadpochechnikov pri lechenii bol'nykh gonoreĭnym vospaleniem organov moshonki proteoliticheskimi fermentami.