[Structural and functional study of polymyxins. Isolation and properties of individual components of polymyxin M].
LPCC and HPLC revealed that polymyxin M was a mixture of five components of the polymyxin nature: PM1, PM2, PMx, PMy and PMz. The individual compounds PM1, PM2 and PMz were isolated. Their physicochemical properties and data on antimicrobial activity are presented.
Trakhanova
M N
MN
Zinchenko
A A
AA
Bairamashvili
D I
DI
Makarova
R A
RA
Samoĭlova
L N
LN
D001419:Bacteria / Q000187:drug effects; D002851:Chromatography, High Pressure Liquid; D011113:Polymyxins / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology
D011113:Polymyxins
Strukturno-funktsional'nye issledovaniia polimiksinov. Vydelenie i svoĭstva individual'nykh komponentov polimiksina M.