title: Diagnostic electron microscopy using fine needle aspiration biopsies.
abstract: Electron microscopy can be a valuable aid to light microscopy in the interpretation of fine needle aspiration biopsies of tumors, but considerable care in procuring and processing the specimen is necessary to recover the tumor cells and avoid altering their fine structure. Fixation followed by filtration through a cloth screen is recommended. Experience with this technique is briefly reviewed.
authors.affiliation: University of Texas M.D. Anderson Hospital and Tumor Institute, Houston 77030.
authors.forename: B
authors.initials: B
authors.lastname: Mackay
authors.forename: T
authors.initials: T
authors.lastname: Fanning
authors.forename: J M
authors.initials: JM
authors.lastname: Bruner
authors.forename: M C
authors.initials: MC
authors.lastname: Steglich
mesh_terms: D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D018288:Carcinoma, Small Cell / Q000175:diagnosis / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007223:Infant; D007890:Leiomyosarcoma / Q000175:diagnosis / Q000648:ultrastructure; D008223:Lymphoma / Q000175:diagnosis / Q000648:ultrastructure; D008297:Male; D008545:Melanoma / Q000175:diagnosis / Q000648:ultrastructure; D008654:Mesothelioma / Q000175:diagnosis / Q000648:ultrastructure; D008854:Microscopy, Electron; D008875:Middle Aged; D009369:Neoplasms / Q000175:diagnosis* / Q000648:ultrastructure; D009447:Neuroblastoma / Q000175:diagnosis / Q000648:ultrastructure