Clear cell chondrosarcoma. A case report with topographic analysis.
A case of clear cell chondrosarcoma located in the right proximal end of the femur is presented. Radiologically, the tumor appeared as a large osteolytic lesion with mottled calcification resembling chondroblastoma. Histologically, the greater portion was made up of tumor cells with abundant clear cytoplasm and usually distinct boundaries, associated with areas of conventional chondrosarcoma. The proportion of the clear cell areas was about 60%, and they were mainly distributed along the tumor periphery. Moreover, myxoid chondrosarcoma-like areas, a feature not previously mentioned in clear cell chondrosarcoma, were observed, occupying about 10% of the tumor area.
Ding
J
J
Second Department of Pathology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Hashimoto
H
H
Tsuneyoshi
M
M
Enjoji
M
M
Masuda
S
S
Ushijima
M
M
D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis / Q000473:pathology*; D002813:Chondrosarcoma / Q000175:diagnosis / Q000473:pathology*; D005269:Femur / Q000473:pathology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male