title: Effects of a dietary fibre supplement to a weight reduction programme on blood pressure. A randomized, double-blind, placebo-controlled study.
abstract: Sixty-two moderately obese (body mass index = 34.8), but normotensive females were treated with a balanced hypocaloric diet providing 1,600 kcal/day and either a 6.5 g dietary fibre supplement or placebo in a randomized, double-blind, parallel group design. During a 12-week treatment programme, weight loss was similar in both groups (4.1 and 4.4 kg, respectively). Initially the blood pressure was 123/76 mmHg in the fibre group compared with 124/74 mmHg in the placebo group (p less than 0.05). In the fibre-treated group a significant fall in diastolic blood pressure by 4 mmHg was found (p less than 0.05). No significant change was seen in the placebo group. It is suggested that dietary fibre may affect blood pressure independently of weight change.
authors.affiliation: Department of Internal Medicine, Gustaf V Research Institute, Karolinska Hospital, Stockholm, Sweden.
authors.forename: S
authors.initials: S
authors.lastname: Rössner
authors.forename: I L
authors.initials: IL
authors.lastname: Andersson
authors.forename: K
authors.initials: K
authors.lastname: Ryttig
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000187:drug effects*; D002986:Clinical Trials as Topic; D004038:Diet, Reducing; D004043:Dietary Fiber / Q000494:pharmacology*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000178:diet therapy*; D011897:Random Allocation