Selective IgA deficiency (SIgAD) in Eastern Nigeria.
Fifteen cases of selective IgA deficiency were found among 3772 children. Six had IgA levels of 0.01 g/l both in their serum and saliva, and had associated allergic disorders. The other nine, who did not have atopic disease, had measurable amounts of IgA in their saliva. This finding supports the belief that the early development of secretory IgA may reduce the chances of the development of allergic disease.
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Department of Chemical Pathology, College of Medicine, University of Nigeria Teaching Hospital, Enugu, Anambra State.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004406:Dysgammaglobulinemia / Q000453:epidemiology*; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000235:genetics / Q000276:immunology; D017098:IgA Deficiency; D007071:Immunoglobulin A, Secretory / Q000032:analysis; D007223:Infant; D008297:Male; D009549:Nigeria; D012463:Saliva / Q000276:immunology
D007071:Immunoglobulin A, Secretory