title: [Cyclic nucleotides in the ontogeny of the chick thymus].
abstract: The dynamics of cAMP and cGMP content of the thymus homogenate from developing chick embryos and chickens was studied during ante- and postnatal development. Changes in the content of cyclic nucleotides bear an oscillatory pattern. At the early stages of embryogenesis (9 to 11 days of incubation) the content of cyclic nucleotides was low and gradually increased by 13 days of incubation. As the development proceeded, the quantitative and qualitative rearrangement of the thymus cellular composition reflected in changes in the content of cyclic nucleotides. At the same time the curves of cyclic nucleotide content became antiphasic. These reciprocal cAMP to cGMP ratios might reflect the cyclic and synchronous reproduction and functional development of the main bulk of the thymus cellular elements. The maximum content of cAMP and the minimum content of cGMP were recorded on the 17th day of embryogenesis.
authors.forename: A V
authors.initials: AV
authors.lastname: Andreev
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Shpolianskiĭ
authors.forename: K N
authors.initials: KN
authors.lastname: Nishanbaev
authors.forename: D Kh
authors.initials: DKh
authors.lastname: Khamidov
mesh_terms: D000818:Animals; D002642:Chick Embryo; D002645:Chickens / Q000378:metabolism*; D000242:Cyclic AMP / Q000032:analysis / Q000378:metabolism*; D006152:Cyclic GMP / Q000032:analysis / Q000378:metabolism*; D013950:Thymus Gland / Q000196:embryology / Q000254:growth & development / Q000378:metabolism*; D013997:Time Factors
chemical_list: D000242:Cyclic AMP; D006152:Cyclic GMP
vernacular_title: Tsiklicheskie nukleotidy v ontogeneze vilochkovoĭ zhelezy kur.