title: [Tl-201 myocardial SPECT in silent myocardial ischemia and angiographically proven coronary heart disease].
abstract: Silent myocardial ischemia is defined as true myocardial ischemia without angina pectoris in patients with angiographically detected coronary artery disease. In this study 52 patients (46 male, 8 female: mean age 53 years) with a pathological exercise test but no symptoms were investigated. They showed stenosis of 75% or more of the diameter in at least one coronary segment on angiography. Prior to or after catheterization (within 14 days) Tl-201 SPECT was done and evaluated independently of angiography. A clear correlation between angiographically confirmed stenosis and reversible perfusion defects with Tl-201 SPECT was established (62 out of 76 lesions). Furthermore, there was a significant relation between angiographically detected subtotal or total occlusions of coronary vessels and irreversible perfusion defects using Tl-201 SPECT (35 in 44 lesions) (p less than 0.001). In patients with ST depression but without angina pectoris during the exercise test, the Tl-201 SPECT is highly suited to determine the hemodynamic effect of coronary stenoses.
authors.affiliation: Medizinische Universitätsklinik, Graz.
authors.forename: B
authors.initials: B
authors.lastname: Eber
authors.forename: P
authors.initials: P
authors.lastname: Lind
authors.forename: J
authors.initials: J
authors.lastname: Dusleag
authors.forename: W
authors.initials: W
authors.lastname: Langsteger
authors.forename: O
authors.initials: O
authors.lastname: Eber
authors.forename: W
authors.initials: W
authors.lastname: Klein
mesh_terms: D000787:Angina Pectoris / Q000000981:diagnostic imaging; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D013794:Thallium Radioisotopes
vernacular_title: Tl-201-Myokard-SPECT bei stummer Myokardischämie und angiographisch gesicherter koronarer Herzkrankheit.