title: DNA topoisomerases: nature's solution to the topological ramifications of the double-helix structure of DNA.
authors.forename: J C
authors.initials: JC
authors.lastname: Wang
mesh_terms: D001426:Bacterial Proteins / Q000502:physiology; D004247:DNA / Q000378:metabolism; D004261:DNA Replication; D004264:DNA Topoisomerases, Type I / Q000378:metabolism / Q000502:physiology*; D004250:DNA Topoisomerases, Type II / Q000378:metabolism / Q000502:physiology*; D004278:DNA, Superhelical / Q000378:metabolism*; D004926:Escherichia coli / Q000201:enzymology; D005057:Eukaryotic Cells / Q000378:metabolism; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D014158:Transcription, Genetic
chemical_list: D001426:Bacterial Proteins; D004278:DNA, Superhelical; D004247:DNA; D004264:DNA Topoisomerases, Type I; D004250:DNA Topoisomerases, Type II