Steroid hormone metabolites potentiate GABA receptor-mediated chloride ion flux with nanomolar potency.
Morrow
A L
AL
Section on Molecular Pharmacology, National Institute of Mental Health, Bethesda, MD 20892.
Suzdak
P D
PD
Paul
S M
SM
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D002540:Cerebral Cortex / Q000187:drug effects / Q000378:metabolism; D002712:Chlorides / Q000378:metabolism*; D066298:In Vitro Techniques; D008297:Male; D009118:Muscimol / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D011963:Receptors, GABA-A / Q000187:drug effects*; D013256:Steroids / Q000494:pharmacology*; D013574:Synaptosomes / Q000187:drug effects / Q000378:metabolism
D002712:Chlorides; D011963:Receptors, GABA-A; D013256:Steroids; D009118:Muscimol