Physico-chemical properties of murine hepatitis virus, strain A 59. Brief report.
The infectivity of murine hepatitis virus (MHV-A59) was optimally stable at pH 6.0 and was unaffected by ionic strength or at least 15 cycles of freezing and thawing. It was completely inactivated within 25 minutes at 56 degrees C, but was protected by 1 M magnesium chloride or magnesium sulphate. It was completely inactivated within 14 days at 37 and 22 degrees C, but was relatively stable for as long as 72 days at 4 degrees C and optimal pH.
Daniel
C
C
Centre de recherche en virologie, Institut Armand-Frappier, Université du Québec, Laval-des-Rapides, Canada.
Talbot
P J
PJ
D000818:Animals; D002460:Cell Line; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006863:Hydrogen-Ion Concentration; D008274:Magnesium / Q000494:pharmacology; D015636:Magnesium Chloride; D051379:Mice; D006517:Murine hepatitis virus / Q000187:drug effects / Q000502:physiology; D013696:Temperature
D015636:Magnesium Chloride; D008274:Magnesium