[High-doses chemotherapy followed by bone marrow autograft in the treatment of small cell bronchial cancer].
Nineteen patients were treated with high dose chemotherapy followed by an autologous bone marrow transplantation. The chemotherapy regimen was an association of BCNU, procarbazine, etoposide, melphalan. Six patients had a progressive disease; 4 short-term complete remissions were observed. In 13 responding patients, 6 maintained complete remissions were noted.
Pico
J L
JL
Institut Gustave-Roussy, Villejuif, France.
Baume
D
D
Ostronoff
M
M
Beaujean
F
F
Gouyette
A
A
Le Chevalier
T
T
Arriagada
R
R
Rebattu
P
P
Hayat
M
M
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D016026:Bone Marrow Transplantation; D018288:Carcinoma, Small Cell / Q000188:drug therapy / Q000628:therapy*; D002330:Carmustine / Q000008:administration & dosage; D003131:Combined Modality Therapy; D005047:Etoposide / Q000008:administration & dosage; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000628:therapy*; D008558:Melphalan / Q000008:administration & dosage; D011344:Procarbazine / Q000008:administration & dosage
D011344:Procarbazine; D005047:Etoposide; D008558:Melphalan; D002330:Carmustine
Chimiothérapie à hautes doses suivie d'autogreffe de moelle osseuse dans le traitement du cancer bronchique à petites cellules.