DNA footprinting with hydroxyl radical.
High resolution images of proteins bound to DNA can be achieved through the use of a simple inorganic chemical system that produces the hydroxyl radical.
Tullius
T D
TD
Department of Chemistry, Johns Hopkins University, Baltimore, Maryland 21218.
D001665:Binding Sites; D055598:Chemical Phenomena; D002621:Chemistry; D004247:DNA / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000378:metabolism*; D004492:Edetic Acid; D005296:Ferrous Compounds; D006878:Hydroxides; D017665:Hydroxyl Radical; D035582:Transcription Factor TFIIIA; D014157:Transcription Factors / Q000378:metabolism
D004268:DNA-Binding Proteins; D005296:Ferrous Compounds; D006878:Hydroxides; D035582:Transcription Factor TFIIIA; D014157:Transcription Factors; C055526:Fe(II)-EDTA; D017665:Hydroxyl Radical; D004247:DNA; D004492:Edetic Acid