Antigenic diversity of infectious bursal disease viruses.
Statistically significant antigenic differences were detected among serotype I infectious bursal disease viruses (IBDV) using the virus-neutralization test. Eight serotype I commercial vaccine strains, five serotype I field strains, and two serotype II field strains were tested. Hyperimmune guinea pig antisera against heterologous and homologous IBDV strains were used in cross-neutralization tests. Relatedness values were calculated from geometric mean antibody titers based on a minimum of three tests. Six subtypes were distinguished among the 13 serotype I strains tested.
Jackwood
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Food Animal Health Research Program, Ohio Agricultural Research and Development Center, Ohio State University, Wooster 44691.
Saif
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D000818:Animals; D000956:Antigens, Viral / Q000145:classification*; D002642:Chick Embryo; D007243:Infectious bursal disease virus / Q000145:classification / Q000276:immunology*; D012087:Reoviridae / Q000276:immunology*; D012703:Serotyping
D000956:Antigens, Viral