Increase in etoposide-induced topoisomerase II-mediated DNA breaks after cell synchronization induced by low doses of methotrexate.
Lorico
A
A
Division of Experimental Oncology 1, Centro di Riferimento Oncologico, Aviano, Italy.
Rappa
G
G
Boiocchi
M
M
Anzanello
F
F
D'Incalci
M
M
D002453:Cell Cycle / Q000187:drug effects; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D004249:DNA Damage; D004250:DNA Topoisomerases, Type II / Q000378:metabolism*; D005047:Etoposide / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D008727:Methotrexate / Q000494:pharmacology
D005047:Etoposide; D004250:DNA Topoisomerases, Type II; D008727:Methotrexate