title: [A case of carcinoma arising from an anal fistula].
abstract: Carcinoma arising from a chronic anal fistula is an uncommon condition. A 53-year-old woman visited our clinic, complaining of refractory anal fistulas that had persisted for over a period of 15 years, which had started to discharge pus and mucus through external fistulous openings several months ago. A cytologic study of the perianal discharges and a biopsy of the external openings were useful in preoperatively detecting a cancer complicating an anal fistula. An abdominoperineal rectal amputation with an extended dissection of the relevant lymph nodes was performed. Histopathological findings revealed a mucus-producing adenocarcinoma with ly1, v0 in vessel invasion, and the stage of cancer was determined as being stage II, H0P0a2n0 (0/129). It is emphasized that cancer should be suspected whenever examining an old fistula, especially one with mucous discharges.
authors.affiliation: Dept. of Surgery II, Kanzawa Med. Univ.
authors.forename: S
authors.initials: S
authors.lastname: Takashima
authors.forename: J
authors.initials: J
authors.lastname: Fukunaga
authors.forename: K
authors.initials: K
authors.lastname: Kushibiki
authors.forename: Y
authors.initials: Y
authors.lastname: Kinami
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D001005:Anus Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D011379:Prognosis; D012003:Rectal Fistula / Q000150:complications* / Q000473:pathology / Q000601:surgery