title: Electron microscopy of the influenza virus submembranal structure.
abstract: Electron micrographs of stain-penetrated influenza virus particles show a variety of internal structures that all consist of units of 4 X 4 nm. Isolated influenza virus M-protein, that is reassociated with lipid, forms very similar structures on liposomes. We therefore conclude that the 4 X 4 nm unit is M-protein. We further argue that the M-protein is not arranged with icosahedral symmetry.
authors.affiliation: Division of Virology, National Institute for Medical Research, London, United Kingdom.
authors.forename: R W
authors.initials: RW
authors.lastname: Ruigrok
authors.forename: L J
authors.initials: LJ
authors.lastname: Calder
authors.forename: S A
authors.initials: SA
authors.lastname: Wharton
mesh_terms: D008081:Liposomes; D008854:Microscopy, Electron; D009698:Nucleoproteins / Q000648:ultrastructure; D009975:Orthomyxoviridae / Q000648:ultrastructure*; D012261:Ribonucleoproteins / Q000648:ultrastructure; D014763:Viral Matrix Proteins / Q000648:ultrastructure; D014771:Virion / Q000648:ultrastructure
chemical_list: D008081:Liposomes; D009698:Nucleoproteins; D012261:Ribonucleoproteins; D014763:Viral Matrix Proteins