title: Terpenoid biotransformation in mammals. V. Metabolism of (+)-citronellal, (+-)-7-hydroxycitronellal, citral, (-)-perillaldehyde, (-)-myrtenal, cuminaldehyde, thujone, and (+-)-carvone in rabbits.
abstract: 1. The metabolism of (+)-citronellal, (+-)-7-hydroxycitronellal, citral, (-)-perillaldehyde, (-)-myrtenal, cuminaldehyde, thujone, and (+-)-carvone was studied in rabbits. 2. In (+-)-7-hydroxycitronellal, (-)-perillaldehyde, (-)-myrtenal and cuminaldehydes, both primary alcohols and carboxylic acids were formed. 3. In (-)-citronellal and citral, regioselective oxidation was found and a trans-positioned methyl group was carboxylated in each case. 4. In o-cuminaldehyde, reduction but not oxidation, was found.
authors.affiliation: Hiroshima Institute of Technology, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ishida
authors.forename: M
authors.initials: M
authors.lastname: Toyota
authors.forename: Y
authors.initials: Y
authors.lastname: Asakawa
mesh_terms: D000080462:Acyclic Monoterpenes; D000818:Animals; D001547:Benzaldehydes / Q000378:metabolism; D000081008:Bicyclic Monoterpenes; D001711:Biotransformation; D002855:Chromatography, Thin Layer; D000081005:Cyclohexane Monoterpenes; D000081007:Cymenes; D008297:Male; D039821:Monoterpenes; D011817:Rabbits; D013056:Spectrophotometry, Ultraviolet; D013729:Terpenes / Q000378:metabolism*
chemical_list: D000080462:Acyclic Monoterpenes; D001547:Benzaldehydes; D000081008:Bicyclic Monoterpenes; D000081005:Cyclohexane Monoterpenes; D000081007:Cymenes; D039821:Monoterpenes; D013729:Terpenes; C033342:perillaldehyde; C006923:carvone; C061545:myrtenal; C020755:hydroxycitronellal; C005790:beta-thujone; C007165:cuminaldehyde; C007078:citronellol; C007076:citral