[Expression of interleukin 2 receptors in in vivo Epstein-Barr virus transformed B lymphocytes].
Interleukin-2 (IL-2) enhances the proliferation of in vivo Epstein-Barr virus-(EBV)-transformed B-cells from patients with a present or past history of infectious mononucleosis. In contrast, there is less expression of functional IL-2 receptors on EBV-transformed B-cells from patients with rheumatoid arthritis. These results suggest differences in the involvement of B-cells in EBV-associated diseases.
Becker
H
H
Universität Giessen, III. Medizinische Klinik und Poliklinik.
Helmke
K
K
Federlin
K
K
D001172:Arthritis, Rheumatoid / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology*; D002472:Cell Transformation, Viral; D004854:Herpesvirus 4, Human / Q000235:genetics* / Q000276:immunology; D006801:Humans; D007244:Infectious Mononucleosis / Q000276:immunology; D007376:Interleukin-2 / Q000378:metabolism; D008213:Lymphocyte Activation; D011971:Receptors, Immunologic / Q000235:genetics*; D015375:Receptors, Interleukin-2
D007376:Interleukin-2; D011971:Receptors, Immunologic; D015375:Receptors, Interleukin-2
Expression von Interleukin-2-Rezeptoren auf in vivo Epstein-Barr-Virus-transformierten B-Lymphozyten.