title: Oral Kaposi's sarcoma in acquired immunodeficiency syndrome. Review of management and report of the efficacy of intralesional vinblastine.
abstract: Treatment of palatal Kaposi's sarcoma (KS) with intralesional injection of vinblastine was seen to provide effective palliation. Of the ten patients studied, four had a 25% to 50% response, two 50% to 75% response, and four had 75% to 100% response with one or two intralesional injections of vinblastine. Response to treatment was followed for a mean of 3.6 months, with recurrence of lesions in two of ten patients.
authors.affiliation: Cancer Control Agency of British Columbia, Vancouver, Canada.
authors.forename: J B
authors.initials: JB
authors.lastname: Epstein
authors.forename: F
authors.initials: F
authors.lastname: Lozada-Nur
authors.forename: W A
authors.initials: WA
authors.lastname: McLeod
authors.forename: J
authors.initials: J
authors.lastname: Spinelli
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000188:drug therapy* / Q000473:pathology; D010157:Palatal Neoplasms / Q000188:drug therapy* / Q000473:pathology; D012514:Sarcoma, Kaposi / Q000188:drug therapy* / Q000473:pathology; D014747:Vinblastine / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D014747:Vinblastine