[A case of two patients with primary lung cancer secreting CA19-9].
We experienced two primary lung cancer patients who showed high levels of CA19-9 (Carbohydrate Antigen 19-9). One case was small cell carcinoma and the other was adenocarcinoma. In contrast to malignancies of digestive organ origin, rare CA19-9 positive cases are reported in lung cancer. To get evidences that these lung cancer tissues were producing CA19-9, PAP stain (Peroxidase anti peroxidase method: Sternberger) was performed, and positive stains were obtained in tumors surgically removed from these two patients. Especially in a patient who showed very high level of CA19-9 (27,369 U/ml), almost every tumor cell was positively stained. From these findings, we suggest the importance of checking CA19-9 in patients with lung cancer.
Nagami
H
H
1st Department of Surgery, Shimane Medical University, Izumo, Japan.
Nohara
T
T
Yamauchi
M
M
Yamada
K
K
Nakase
A
A
D000230:Adenocarcinoma / Q000276:immunology* / Q000378:metabolism; D000368:Aged; D000951:Antigens, Neoplasm / Q000032:analysis*; D015295:Antigens, Tumor-Associated, Carbohydrate; D018288:Carcinoma, Small Cell / Q000276:immunology* / Q000378:metabolism; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000276:immunology* / Q000378:metabolism; D008297:Male; D008875:Middle Aged
D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate