Low-dose cytosine arabinoside-induced remission of lymphoblastic leukemia in a cat.
Low-dose cytosine arabinoside (10 mg/m2, q 12 h), an antimetabolite chemotherapeutic agent, was administered subcutaneously to a cat with aleukemic lymphoblastic leukemia. After several weeks of this treatment, there was marked improvement in the neutrophil count and PCV, as well as restoration of adequate numbers of normal bone marrow cells. The remission lasted 10 weeks.
Helfand
S C
SC
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010.
D000818:Animals; D002371:Cat Diseases / Q000188:drug therapy*; D002415:Cats; D003561:Cytarabine / Q000627:therapeutic use*; D007938:Leukemia / Q000188:drug therapy / Q000662:veterinary*; D005256:Leukemia Virus, Feline; D007945:Leukemia, Lymphoid / Q000188:drug therapy / Q000662:veterinary*; D012074:Remission Induction
D003561:Cytarabine