Eaton-Lambert syndrome as a harbinger of recurrent small-cell carcinoma of the cervix with improvement after combination chemotherapy.
Eaton-Lambert or myasthenic syndrome was diagnosed in a young woman with recurrent small-cell carcinoma of the cervix. Therapy with vincristine, doxorubicin, and cyclophosphamide resulted in a partial response of the tumor and marked improvement in neurologic symptoms. Diagnosis and treatment of this paraneoplastic syndrome are discussed.
Sutton
G P
GP
Department of Obstetrics and Gynecology, Indiana University, School of Medicine, Indianapolis.
Siemers
E
E
Stehman
F B
FB
Ehrlich
C E
CE
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D018288:Carcinoma, Small Cell / Q000150:complications / Q000188:drug therapy / Q000556:secondary*; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008479:Mediastinal Neoplasms / Q000188:drug therapy / Q000556:secondary*; D010257:Paraneoplastic Syndromes / Q000188:drug therapy / Q000209:etiology*; D002583:Uterine Cervical Neoplasms; D014750:Vincristine / Q000008:administration & dosage
D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide