Epstein-Barr virus and epithelial cells: implications for the otolaryngologist.
Epstein-Barr Virus (EBV) is an oncogenic herpesvirus associated with two human malignancies. Initially linked in the etiology of Burkitt's lymphoma, a B cell lymphoma, it has subsequently been implicated in the causation of nasopharyngeal carcinoma, an epithelial tumor of considerable world health importance. More recently a number of head and neck tumors have been shown to harbor the virus, suggesting a possible role for EBV in their development.
Clark
D R
DR
Department of Cancer Studies, University of Birmingham Medical School, England.
Young
L S
LS
Proops
D W
DW
D002051:Burkitt Lymphoma / Q000382:microbiology; D002277:Carcinoma / Q000382:microbiology*; D004848:Epithelium / Q000382:microbiology; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D007972:Leukoplakia, Oral / Q000382:microbiology; D009303:Nasopharyngeal Neoplasms / Q000382:microbiology*; D014779:Virus Replication