Hydroxyurea, methotrexate and adriblastine can mediate non-enzymatic reduction of nitroblue tetrazolium with NADH which is inhibited by superoxide dismutase.
Przybyszewski
W M
WM
Department of Biochemistry, Institute of Haematology, Warsaw, Poland.
Malec
J
J
D000903:Antibiotics, Antineoplastic / Q000494:pharmacology*; D004317:Doxorubicin / Q000494:pharmacology*; D005609:Free Radicals; D006918:Hydroxyurea / Q000494:pharmacology*; D008727:Methotrexate / Q000494:pharmacology*; D009243:NAD / Q000494:pharmacology*; D009580:Nitroblue Tetrazolium / Q000378:metabolism*; D010084:Oxidation-Reduction; D013482:Superoxide Dismutase / Q000494:pharmacology*; D013481:Superoxides / Q000378:metabolism; D013778:Tetrazolium Salts / Q000378:metabolism*
D000903:Antibiotics, Antineoplastic; D005609:Free Radicals; D013778:Tetrazolium Salts; D009243:NAD; D013481:Superoxides; D009580:Nitroblue Tetrazolium; D004317:Doxorubicin; D013482:Superoxide Dismutase; D006918:Hydroxyurea; D008727:Methotrexate