title: Antigenic and restriction endonuclease analyses of new adenovirus types 19 and 37 causing acute conjunctivitis.
abstract: DNA restriction endonuclease cleavage analysis and serum neutralization test were performed in strains of adenovirus types 19 (Ad-19) and 37 (Ad-37) isolated from patients with acute conjunctivitis in Sapporo (Japan), Kaohsiung (Taiwan) and Pusan (South Korea) during the period of 1977 to 1984. Ad-19 and Ad-37 could be roughly differentiated, but a fair degree of cross reactivity was noted by serological test. By DNA restriction endonuclease analysis, Ad-19 isolates, Ad-19 prototype strain and Ad-37 strains were clearly differentiated. It was suggested by DNA cleavage patterns that both Ad-19 and Ad-37 isolates in East Asia are the same as those currently found in Europe and the USA. A new subtype of Ad-37 was found by DNA cleavage analysis among the isolates obtained in Sapporo and Kaohsiung in 1980.
authors.affiliation: Department of Ophthalmology, Hokkaido University School of Medicine, Sapporo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Higuchi
authors.forename: N
authors.initials: N
authors.lastname: Nakazono
authors.forename: K
authors.initials: K
authors.lastname: Ishii
authors.forename: S
authors.initials: S
authors.lastname: Ohno
authors.forename: H
authors.initials: H
authors.lastname: Matsuda
authors.forename: S
authors.initials: S
authors.lastname: Fujii
authors.forename: K
authors.initials: K
authors.lastname: Fujinaga
authors.forename: K
authors.initials: K
authors.lastname: Kondo
mesh_terms: D000208:Acute Disease; D000257:Adenoviridae Infections; D000258:Adenovirus Infections, Human; D000260:Adenoviruses, Human / Q000145:classification / Q000235:genetics / Q000276:immunology*; D000956:Antigens, Viral / Q000032:analysis*; D001208:Asia; D003231:Conjunctivitis / Q000209:etiology*; D004262:DNA Restriction Enzymes; D006801:Humans
chemical_list: D000956:Antigens, Viral; D004262:DNA Restriction Enzymes