title: Antigenic diversity of infectious bursal disease viruses.
abstract: Statistically significant antigenic differences were detected among serotype I infectious bursal disease viruses (IBDV) using the virus-neutralization test. Eight serotype I commercial vaccine strains, five serotype I field strains, and two serotype II field strains were tested. Hyperimmune guinea pig antisera against heterologous and homologous IBDV strains were used in cross-neutralization tests. Relatedness values were calculated from geometric mean antibody titers based on a minimum of three tests. Six subtypes were distinguished among the 13 serotype I strains tested.
authors.affiliation: Food Animal Health Research Program, Ohio Agricultural Research and Development Center, Ohio State University, Wooster 44691.
authors.forename: D H
authors.initials: DH
authors.lastname: Jackwood
authors.forename: Y M
authors.initials: YM
authors.lastname: Saif
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000145:classification*; D002642:Chick Embryo; D007243:Infectious bursal disease virus / Q000145:classification / Q000276:immunology*; D012087:Reoviridae / Q000276:immunology*; D012703:Serotyping
chemical_list: D000956:Antigens, Viral