[Effect of ionizing radiation on the functional state of snail neurons. Cyclic nucleotide levels and phosphorylation of membrane proteins].
A study was made of the effect of ionizing radiation, phospholipase A2, and low concentrations of mediators (for instance, acetylcholine and gamma-aminobutyric acid) on the content of cyclic nucleotides and phosphorylation of membrane proteins of Helix pomatia nervous ganglia. Ionizing radiation was shown to decrease considerably the levels of cAMP and cGMP which correlated with the diminution of membrane phosphorylation. Phospholipase A2 and low doses of mediators produced a modifying effect on the cyclic nucleotide content.
Dvoretskiĭ
A I
AI
Egorova
E G
EG
Shainskaia
A M
AM
Azatian
K V
KV
Aĭrapetian
S N
SN
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism* / Q000528:radiation effects; D006152:Cyclic GMP / Q000378:metabolism* / Q000528:radiation effects; D006372:Helix, Snails; D008565:Membrane Proteins / Q000378:metabolism* / Q000528:radiation effects; D009474:Neurons / Q000378:metabolism / Q000528:radiation effects*; D010766:Phosphorylation; D011829:Radiation Dosage; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology
D008565:Membrane Proteins; D005680:gamma-Aminobutyric Acid; D000242:Cyclic AMP; D006152:Cyclic GMP; D000109:Acetylcholine
Deĭstvie ioniziruiushcheĭ radiatsii na funktsional'noe sostoianie neĭronov vinogradnoĭ ulitki. Soderzhanie tsiklicheskikh nukleotidov i fosforilirovanie membrannykh belkov.