Polarized membrane domains of fibroblasts.
Data on the heterogeneous distribution of various membrane domains on the surface of fibroblasts are reviewed. Polarized localization of negative charges is demonstrated and new results on the development and maintenance of polarity in primary human fibroblasts are presented. Cell membrane heterogeneity in fibroblasts and in other cells is compared. Our results indicate that the regional localization of membrane domains of fibroblasts, and their dependence on cell movement and cell contacts is in several aspects similar to that described for epithelial cells.
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Frédéric Joliot-Curie, National Research Institute for Radiobiology and Radiohygiene, Budapest, Hungary.
Kubasova
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Köteles
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GJ
D000818:Animals; D002450:Cell Communication; D002460:Cell Line; D002462:Cell Membrane / Q000502:physiology / Q000648:ultrastructure; D002465:Cell Movement; D004594:Electrophysiology; D005347:Fibroblasts / Q000166:cytology* / Q000502:physiology / Q000648:ultrastructure; D006801:Humans; D051379:Mice; D008854:Microscopy, Electron