Polarized light microscopic examination of human bile in the diagnosis of microlithiasis of the gallbladder.
Of the 20 cases with biliary colics who had normal OCG and ultrasound, 11 (55%) showed microlithiasis in the form of cholesterol monohydrate crystals and/or calcium bilirubinate granules on polarized light microscopy of the duodenal bile. Microlithiasis was noted in gallbladder bile of all (100%) the cases with proven gallstones but in none of the duodenal bile samples from healthy subjects. This study suggests that polarized microscopy may be a useful method to detect microlithiasis in patients with repeated biliary colics who have normal OCG and ultrasound examination.
Gogna
A
A
Kar
P
P
Acharya
N R
NR
Anand
V J
VJ
Kapoor
R
R
D001646:Bile / Q000032:analysis*; D002769:Cholelithiasis / Q000032:analysis / Q000175:diagnosis*; D003085:Colic / Q000175:diagnosis*; D006801:Humans; D008859:Microscopy, Polarization