title: Treatment of unruptured ectopic pregnancy by needling of sac and injection of methotrexate or PG E2 under transvaginal sonography control. Report of 10 cases.
abstract: We report transvaginal puncture of ectopic pregnancy and instillation therapy under sonographic control in 10 cases. Only patients with rising beta-hCG levels were selected for treatment. In 9 cases we instilled methotrexate and in 1 case prostaglandin E2. A successful outcome was obtained in 8 patients, 7 had been treated with methotrexate and 1 with PG E2. Conservative treatment failed in two patients. However, these patients were already in the 10th and 8th week of pregnancy, respectively. There were no side effects after methotrexate; the patient given PG E2 experienced severe discomfort, vomiting and cramps.
authors.affiliation: Institute of Sterility Treatment, Vienna, Austria.
authors.forename: W
authors.initials: W
authors.lastname: Feichtinger
authors.forename: P
authors.initials: P
authors.lastname: Kemeter
mesh_terms: D000032:Abortion, Therapeutic / Q000379:methods; D000328:Adult; D015232:Dinoprostone / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage / Q000627:therapeutic use*; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011274:Pregnancy, Tubal / Q000188:drug therapy*; D013396:Suction; D014465:Ultrasonics
chemical_list: D015232:Dinoprostone; D008727:Methotrexate