title: Developmental regulation and identification of an isotype encoded by altB, an alpha-tubulin locus in Physarum polycephalum.
abstract: A subcloned portion of the 5' nontranslated sequence from a Physarum alpha-tubulin cDNA is specific for a single alpha-tubulin locus, altB, of Physarum polycephalum. We find that this locus is expressed only in the plasmodium and encodes at least an alpha 1-tubulin isotype, which we have designated alpha 1B. Hybridization patterns of other subclones of this cDNA reveal two sequences for alpha-tubulin at the altB locus.
authors.affiliation: McArdle Laboratory for Cancer Research, University of Wisconsin, Madison 53706.
authors.forename: L L
authors.initials: LL
authors.lastname: Green
authors.forename: M M
authors.initials: MM
authors.lastname: Schroeder
authors.forename: M A
authors.initials: MA
authors.lastname: Diggins
authors.forename: W F
authors.initials: WF
authors.lastname: Dove
mesh_terms: D004262:DNA Restriction Enzymes; D004271:DNA, Fungal / Q000235:genetics; D005786:Gene Expression Regulation; D005800:Genes, Fungal; D008870:Microtubules / Q000502:physiology*; D010804:Physarum / Q000235:genetics* / Q000254:growth & development; D012333:RNA, Messenger / Q000235:genetics; D008941:Spindle Apparatus / Q000502:physiology; D014404:Tubulin / Q000235:genetics*
chemical_list: D004271:DNA, Fungal; D012333:RNA, Messenger; D014404:Tubulin; D004262:DNA Restriction Enzymes