title: Infiltrating ductal carcinoma developing within cystosarcoma phyllodes--a case report.
abstract: Malignancy in cystosarcoma phyllodes is uncommon and often confined to the stromal element. An extremely rare case of infiltrating ductal carcinoma developing within the stroma of cystosarcoma phyllodes is reported herein. A breast tumor with a diameter of 15 cm, which was diagnosed as cystosarcoma phyllodes, was excised from the right breast of a 47-year old woman. The histopathological examination revealed that hyperplastic ductal epithelial cells with dark cytoplasm and enlarged hyperchromatic nuclei were infiltrating the stroma. Thus, a diagnosis of ductal carcinoma within cystosarcoma was made. Subsequently, a standard radical mastectomy was performed. No recurrence or metastasis has been observed over the post-operative period of 5 years and 6 months.
authors.affiliation: Second Department of Surgery, Kyoto Prefectural University of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yasumura
authors.forename: S
authors.initials: S
authors.lastname: Matsui
authors.forename: T
authors.initials: T
authors.lastname: Hamajima
authors.forename: K
authors.initials: K
authors.lastname: Nagashima
authors.forename: H
authors.initials: H
authors.lastname: Yamagishi
authors.forename: I
authors.initials: I
authors.lastname: Aikawa
authors.forename: T
authors.initials: T
authors.lastname: Oka
authors.forename: T
authors.initials: T
authors.lastname: Nakae
authors.forename: N
authors.initials: N
authors.lastname: Shimada
mesh_terms: D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D003557:Phyllodes Tumor / Q000473:pathology*