title: Production of eicosapentaenoic acid by marine bacteria.
abstract: About 5,000 strains of marine microorganisms were screened for eicosapentaenoic acid (EPA)-producing ability, which was detected in 88 of them. All of the latter were found to be obligate aerobic, Gram-negative, motile, short rod-shaped bacteria. One strain, designated as SCRC-8132, showed a doubling time of 30 min at 25 degrees C and produced 20 mg/liter (4 mg/g dry cells) when cultured in a P-Y-M-Glucose medium for 18 h. The EPA to total fatty acids ratio was 24%. The strain produced 26 mg EPA/liter (15 mg/g dry cells) when cultured at 4 degrees C for 5 days, the EPA ratio being increased to 40%.
authors.affiliation: Sagami Chemical Research Center, Kanagawa.
authors.forename: K
authors.initials: K
authors.lastname: Yazawa
authors.forename: K
authors.initials: K
authors.lastname: Araki
authors.forename: N
authors.initials: N
authors.lastname: Okazaki
authors.forename: K
authors.initials: K
authors.lastname: Watanabe
authors.forename: C
authors.initials: C
authors.lastname: Ishikawa
authors.forename: A
authors.initials: A
authors.lastname: Inoue
authors.forename: N
authors.initials: N
authors.lastname: Numao
authors.forename: K
authors.initials: K
authors.lastname: Kondo
mesh_terms: D001419:Bacteria / Q000302:isolation & purification / Q000378:metabolism*; D001420:Bacteria, Aerobic / Q000378:metabolism; D015118:Eicosapentaenoic Acid / Q000378:metabolism*; D006090:Gram-Negative Bacteria / Q000378:metabolism; D012623:Seawater; D014871:Water Microbiology
chemical_list: D015118:Eicosapentaenoic Acid