title: [Effect of cyclic 3',5'-adenosine monophosphate on hyaluronate hydrolase activity in the renal papilla].
abstract: The relationships between cAMP and hyaluronate hydrolases (HH) activity were studied in the renal tissue. Both the urine osmolality and the HH activity were increased in the papilla tissue of rats treated with cAMP. Incubation of mild homogenized cells prepared from kidney papilla with cAMP, resulted in a significant increase in the total HH activity and that of beta-glucuronidase and N-acetyl-beta-D-hexosaminidase, whereas the activity of hyaluronidase remained unchanged. The data obtained suggest that ADH effect on the HH activity is mediated by adenylate cyclase mechanism.
authors.forename: T E
authors.initials: TE
authors.lastname: Goriunova
authors.forename: L N
authors.initials: LN
authors.lastname: Ivanova
authors.forename: I N
authors.initials: IN
authors.lastname: Kolosova
mesh_terms: D000818:Animals; D000242:Cyclic AMP / Q000494:pharmacology*; D006821:Hyaluronoglucosaminidase / Q000378:metabolism*; D007679:Kidney Medulla / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D051381:Rats
chemical_list: D000242:Cyclic AMP; D006821:Hyaluronoglucosaminidase
vernacular_title: Vliianie tsiklicheskogo 3',5'-adenozinmonofosfata na aktivnost' gialuronatgidrolaz sosochka pochki.