Molecular epidemiology of two consecutive outbreaks of adenovirus 8 keratoconjunctivitis.
Eleven strains of adenovirus 8 (Ad 8) isolated during two consecutive outbreaks of epidemic keratoconjunctivitis (EKC) in the Ophthalmology Department of a University Hospital in France were compared by DNA restriction analysis. The results indicated that isolates from the two outbreaks belong to the same genome type, which is also the most predominant genome type of Ad 8. The usefulness of molecular epidemiology in Ad 8 infections is briefly discussed.
Chastel
C
C
Department of Microbiology and Public Health, Faculty of Medicine, Brest, France.
Adrian
T
T
Demazure
M
M
Legrand-Quillien
M C
MC
Lejeune
B
B
Colin
J
J
Wigand
R
R
D000257:Adenoviridae Infections / Q000453:epidemiology*; D000258:Adenovirus Infections, Human / Q000453:epidemiology* / Q000382:microbiology; D000260:Adenoviruses, Human / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004279:DNA, Viral / Q000235:genetics / Q000302:isolation & purification; D004196:Disease Outbreaks; D004812:Epidemiologic Methods; D005260:Female; D005602:France; D006801:Humans; D007637:Keratoconjunctivitis / Q000453:epidemiology* / Q000382:microbiology; D008297:Male; D008875:Middle Aged
D004279:DNA, Viral