[Low-molecular weight heparins in post-surgical recovery].
Low molecular weight heparins are used in human therapy for preventing venous thrombosis during the postoperative period. The monitoring of this therapy uses a measurement of the factor Xla activity. A value of this activity higher than 0.4 IU/ml, suggests a hemorrhage risk. The use of these low molecular weight heparins for the treatment of venous thrombosis is now under investigation. However, the biological monitoring of this treatment has not yet been defined. The anti IIa and anti Xa activities seem to be interesting. In fact the antithrombotic power would be due to the anti IIa and profibrinolytic activities.
Doutremepuich
C
C
Laboratoire d'Hématologie, Faculté de Pharmacie, Bordeaux.
Anne
M C
MC
Fernandez
G
G
Pereira
F
F
de Seze
O
O
Doutremepuich
F
F
D000818:Animals; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use*; D006801:Humans; D011183:Postoperative Complications / Q000517:prevention & control*; D013924:Thrombophlebitis / Q000517:prevention & control*
D006495:Heparin, Low-Molecular-Weight
Les héparines de bas poids moléculaire en réanimation post-chirurgicale.