title: [The role of the immune system in the development of rhinosinusogenous intracranial complications (abscess, arachnoiditis)].
abstract: The article analyses the results of some modern immunological methods of examination in 49 patients with various rhinosinusogenous intracranial complications. It was found that secondary immunodeficiency develops in this group of patients, which is often attended with an autoimmune component. Both the nonspecific defence factors and the organism's specific immune response are impaired in this case. There was a direct relationship between the depth of the immunity disorders and the severity of the clinical course of the disease. The results obtained may be used as auxiliary and prognostic criteria in appraising the patients' condition. The results of the study indicate that rhinosinusogenous intracranial complications should be managed by pathogenetically substantiated therapy with the use of immunocorrective agents in a complex with other types of treatment.
authors.forename: N S
authors.initials: NS
authors.lastname: Blagoveshchenskaia
authors.forename: N Z
authors.initials: NZ
authors.lastname: Mukhamedzhanov
mesh_terms: D000328:Adult; D000911:Antibodies, Monoclonal; D001100:Arachnoiditis / Q000209:etiology* / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology; D001922:Brain Abscess / Q000209:etiology* / Q000276:immunology; D005260:Female; D006801:Humans; D007107:Immune System / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D010587:Phagocytosis / Q000276:immunology; D012220:Rhinitis / Q000150:complications*; D012852:Sinusitis / Q000150:complications*; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal
vernacular_title: Rol' immunnoĭ sistemy v razvitii rinosinusogennykh vnutricherepnykh oslozhneniĭ (abstsess, arakhnoidit).