Solitary condylomatous papilloma of the bronchus.
Two case reports of solitary bronchial papillomas are presented. The histologic features of the lesions are those of squamous papillomas exhibiting prominent condylomatous changes. Immunoperoxidase stains revealed the presence of human papillomavirus antigens in the koilocytotic cells. Ultrastructural studies demonstrated possible intranuclear viral-size particles. Solitary condylomatous papillomas of the bronchus should be distinguished from solitary bronchial squamous papillomas that do not have condylomatous features. The rationale for this separation is the likelihood of a viral origin for these condylomatous papillomas and their potential for malignant change.
Trillo
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Department of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada.
Guha
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D000368:Aged; D001984:Bronchial Neoplasms / Q000382:microbiology / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D010212:Papilloma / Q000382:microbiology / Q000473:pathology* / Q000648:ultrastructure; D027383:Papillomaviridae / Q000302:isolation & purification; D014771:Virion / Q000302:isolation & purification