title: [Clinico-morphological characteristics of the polycystic ovary syndrome].
abstract: 56 patients, 22 to 34 years old, with the syndrome of polycystic ovaries (SPO) were under observation. All of them underwent laparoscopic surgical correction with the abrasion of the uterus and subsequent histological examination. Primary chronic increase of the serum luteinizing hormone (LH) with the relative decrease of the level of the follicle-stimulating hormone (FSH), this resulting in the considerable increase of the LH/FSH ratio. The imbalance of the gonadotropic hormones resulted in the pronounced degenerations of granulosa and theca cells, decrease in the oestradiol and progesterone production and the increase of the androgen level. Morphologically, the rapid death of the developing follicles with their subsequent sclerotic and cystic transformation was observed as well as a sclerosis of tunics and cortical zone of the ovaries, the increase of their size. Obligatory clinical signs of SPO were, besides the sterility, oligomenorrhea starting from the menarche; facultative signs were the obesity and hirsutism in the puberty.
authors.forename: N K
authors.initials: NK
authors.lastname: Permiakov
authors.forename: E A
authors.initials: EA
authors.lastname: Alieva
mesh_terms: D000328:Adult; D001706:Biopsy; D004717:Endometrium / Q000378:metabolism / Q000473:pathology; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood; D006065:Gonadotropins, Pituitary / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D010053:Ovary / Q000378:metabolism / Q000473:pathology; D010503:Periodic Acid-Schiff Reaction; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000473:pathology*; D011863:Radioimmunoassay
chemical_list: D012739:Gonadal Steroid Hormones; D006065:Gonadotropins, Pituitary; D006854:Hydrocortisone
vernacular_title: Kliniko-morfologicheskaia kharakteristika sindroma polikistoznykh iaichnikov.