The identification of T2; the phosphate/pyrophosphate transport protein of the hepatic microsomal glucose-6-phosphatase system.
The phosphate/pyrophosphate translocase protein (T2) of the hepatic microsomal glucose-6-phosphatase system was identified and then purified using antibodies raised against the rat mitochondrial phosphate/hydroxyl ion antiport protein. The T2 protein was shown to be absent in the microsomes isolated from a patient previously diagnosed as having type lc glycogen storage disease.
Waddell
I D
ID
Department of Medicine, Ninewells Hospital and Medical School, University of Dundee, Scotland.
Lindsay
J G
JG
Burchell
A
A
D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism*; D004591:Electrophoresis, Polyacrylamide Gel; D005952:Glucose-6-Phosphatase / Q000378:metabolism*; D006801:Humans; D007163:Immunosorbent Techniques; D008862:Microsomes, Liver / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains
D002352:Carrier Proteins; D005952:Glucose-6-Phosphatase