[Cyclic nucleotides during radiotherapy of breast cancer].
Levels of cAMP and cGMP were higher in breast cancer tissue as compared with benign tumors. Large-fraction irradiation was followed by a decrease in cGMP concentration matched by a rise in cAMP/cGMP ratio in cases of radiosensitive tumors. Small-fraction treatment did not affect cyclic nucleotide levels. Radiotherapy was followed by a decrease in initially raised blood plasma cyclic nucleotide concentration.
Lozinskaia
I N
IN
Iakimova
T P
TP
D000232:Adenofibroma / Q000032:analysis / Q000532:radiotherapy; D001943:Breast Neoplasms / Q000032:analysis / Q000532:radiotherapy*; D000242:Cyclic AMP / Q000032:analysis*; D006152:Cyclic GMP / Q000032:analysis*; D005260:Female; D005348:Fibrocystic Breast Disease / Q000032:analysis / Q000532:radiotherapy; D006801:Humans
D000242:Cyclic AMP; D006152:Cyclic GMP
Tsiklicheskie nukleotidy pri luchevoĭ terapii raka molochnoĭ zhelezy.