Software for genome mapping by fingerprinting techniques.
A genome mapping package has been developed for reading and assembling data from clones analysed by restriction enzyme fragmentation and polyacrylamide gel electrophoresis. The package comprises: data entry; matching; assembly; statistical analysis; modelling. Data entry can be either manual or by a semiautomatic system based on a scanning densitometer. The primary emphasis in the analytical routines is on flexibility and interactive convenience, so that the operator has full knowledge of and control over the growing map, but a variety of automatic options are included. The package continually grows to meet the needs of the Caenorhabditis project.
Sulston
J
J
MRC Laboratory of Molecular Biology, Cambridge, UK.
Mallett
F
F
Staden
R
R
Durbin
R
R
Horsnell
T
T
Coulson
A
A
D001483:Base Sequence; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics / Q000302:isolation & purification; D004262:DNA Restriction Enzymes; D003628:Database Management Systems; D004591:Electrophoresis, Polyacrylamide Gel; D012984:Software
D004247:DNA; D004262:DNA Restriction Enzymes