title: Conditions for radioiodination of antithrombin III retaining its biological properties.
abstract: In order to obtain a radioiodinated antithrombin III (AT III) with a good labelling yield and optimal biological properties towards heparin, thrombin and its anti-AT III monoclonal antibodies, we compared the classical labelling methods and found them wanting. Thus, we perfected a new labelling procedure which fulfils the above requirements.
authors.affiliation: CNRS No. 48 Haemocompatible Polymers, CHU Bordeaux, France.
authors.forename: J
authors.initials: J
authors.lastname: Caix
authors.forename: A
authors.initials: A
authors.lastname: Perrot Minnot
authors.forename: A
authors.initials: A
authors.lastname: Beziade
authors.forename: L
authors.initials: L
authors.lastname: Vuillemin
authors.forename: F
authors.initials: F
authors.lastname: Belloc
authors.forename: C
authors.initials: C
authors.lastname: Baquey
authors.forename: D
authors.initials: D
authors.lastname: Ducassou
mesh_terms: D000990:Antithrombin III / Q000302:isolation & purification / Q000378:metabolism* / Q000592:standards; D002846:Chromatography, Affinity; D006493:Heparin / Q000378:metabolism; D006801:Humans; D007457:Iodine Radioisotopes; D011786:Quality Control; D011865:Radioisotope Dilution Technique; D013917:Thrombin / Q000378:metabolism
chemical_list: D007457:Iodine Radioisotopes; D000990:Antithrombin III; D006493:Heparin; D013917:Thrombin