[The effect of a superoxide dismutase compound on the level of endogenous superoxide dismutase and lipid peroxidation in thermal burns].
Content and activity of endogenous superoxide dismutase (SOD) were decreased simultaneously with an increase in the rate of lipid peroxidation under conditions of burns trauma. At the same time, parameters of the EPR signal were unaltered. Administration of exogenous SOD normalized the patterns studied and increased distinctly the survival rate of rats.
Agadzhanov
M I
MI
Simonian
M A
MA
Kazarian
Sh A
ShA
D000818:Animals; D002056:Burns / Q000201:enzymology* / Q000378:metabolism / Q000401:mortality; D015227:Lipid Peroxidation; D008099:Liver / Q000201:enzymology; D008297:Male; D051381:Rats; D013482:Superoxide Dismutase / Q000378:metabolism / Q000494:pharmacology*
D013482:Superoxide Dismutase
Vliianie preparata superoksiddismutazy na soderzhanie éndogennoĭ superoksiddismutazy i perekisnoe okislenie lipidov pri termicheskikh ozhogakh.