Malignant fibrous histiocytoma in a bonnet macaque (Macaca radiata).
Spontaneous sarcomas, not associated with an underlying disease, appear to be relatively rare in nonhuman primates. Since 1970, there have been few reported cases of naturally-occurring sarcomas of any kind in these species. A malignant histiocytoma and malignant fibrous histiocytoma have been described in a rhesus macaque and baboon, respectively. A malignant fibrous histiocytoma is defined as a sarcoma of varied pattern consisting of a mixture of histiocytic and fibroblastic elements. It is thought that the two cells types arise from a common precursor or that the fibroblastic elements are derived from the histiocytes. These tumors are relatively common in humans. Here we report a case of spontaneously-occurring malignant fibrous histiocytoma in an adult bonnet macaque.
Skavlen
P A
PA
Animal Resource Center, University of Colorado Health Sciences Center, Denver 80262.
Speers
W C
WC
Peterson
R R
RR
Stevens
J O
JO
Reite
M L
ML
D000818:Animals; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology / Q000556:secondary / Q000662:veterinary*; D008175:Lung Neoplasms / Q000556:secondary / Q000662:veterinary*; D008251:Macaca; D008255:Macaca radiata; D008297:Male; D008992:Monkey Diseases / Q000473:pathology*; D009364:Neoplasm Recurrence, Local; D012878:Skin Neoplasms / Q000473:pathology / Q000662:veterinary*