title: [The role of the modification of cyclic purine nucleotide molecule in the regulation of platelet acid glycosidase activity].
abstract: 3'5'-cGMP activated beta-glucuronidase, beta-galactosidase, beta-glucosidase and N-acetyl-beta-glucosaminidase in blood platelets, while 2'3'-cGMP, 3,5'-cGMP, N2O2'-dipalmitoyl and 5'-GMP did not affect the activity of these glycosidases. The guanylate cyclase system appears to be involved in activation of blood platelets glycosidases since it is well known that 3'5'-cGMP activates the thrombocyte protein kinase.
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Petrovich
authors.forename: N F
authors.initials: NF
authors.lastname: Trusova
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000201:enzymology*; D006152:Cyclic GMP / Q000031:analogs & derivatives / Q000502:physiology*; D006026:Glycoside Hydrolases / Q000097:blood*; D006868:Hydrolysis; D010766:Phosphorylation; D051381:Rats
chemical_list: D006026:Glycoside Hydrolases; D006152:Cyclic GMP
vernacular_title: Rol' modifikatsii molekuly purinovogo tsiklonukleotida v reguliatsii aktivnosti kisloĭ glikozidazy trombotsitov.