Family of human Na+, K+-ATPase genes. Structure of the gene for the catalytic subunit (alpha III-form) and its relationship with structural features of the protein.
The primary structure of a gene of the Na+, K+-ATPase multigenic family in the human genome has been determined. The gene corresponds to a hypothetical alpha III-form of the enzyme catalytic subunit. The gene comprises over 25,000 bp, and its protein coding region includes 23 exons and 22 introns. Possible correlation between structural features of the protein and location of introns in the gene are discussed.
Ovchinnikov YuA
Shemyakin Institute of Bioorganic Chemistry, USSR Academy of Sciences, Moscow.
Monastyrskaya
G S
GS
Broude
N E
NE
Ushkaryov YuA
Melkov
A M
AM
Smirnov YuV
Malyshev
I V
IV
Allikmets
R L
RL
Kostina
M B
MB
Dulubova
I E
IE
D000595:Amino Acid Sequence; D000818:Animals; D010582:Bacteriophage lambda / Q000235:genetics; D001482:Base Composition; D001483:Base Sequence; D001665:Binding Sites; D002384:Catalysis; D004247:DNA / Q000235:genetics; D004274:DNA, Recombinant; D005091:Exons; D006801:Humans; D007438:Introns; D008969:Molecular Sequence Data; D000254:Sodium-Potassium-Exchanging ATPase / Q000235:genetics*
D004274:DNA, Recombinant; D004247:DNA; D000254:Sodium-Potassium-Exchanging ATPase