[Functional capacity of the kidneys in whole-body irradiated rats protected with gammaphos and merkamine].
In experiments with Wistar rats it was shown that gammaphos promotes the recovery of the kidneys' filtration function at early times after 7.4 Gy gamma-irradiation and inhibits it after 210 days. Merkamine induces haemodynamic and functional disorders in the exposed rat kidneys within the first 30 days after irradiation.
Sukhacheva
E I
EI
Semenov
D I
DI
Masna
V M
VM
Men'shikova
G A
GA
D004999:Amifostine / Q000009:adverse effects / Q000627:therapeutic use*; D000818:Animals; D003538:Cystamine / Q000009:adverse effects / Q000627:therapeutic use*; D004353:Drug Evaluation, Preclinical; D005260:Female; D005720:Gamma Rays; D007668:Kidney / Q000187:drug effects / Q000503:physiopathology / Q000528:radiation effects*; D009946:Organothiophosphorus Compounds / Q000627:therapeutic use*; D051381:Rats; D011919:Rats, Inbred Strains; D014916:Whole-Body Irradiation / Q000009:adverse effects*
D009946:Organothiophosphorus Compounds; D004999:Amifostine; D003538:Cystamine
Izuchenie funktsional'noĭ sposobnosti pochek total'nogo obluchennykh krys pri zashchite gammafosom i merkaminom.