title: Glucagonoma syndrome.
abstract: A 53-year-old Japanese man with a skin eruption characteristic of glucagonoma syndrome had had misdiagnoses for 10 years. The plasma glucagon level was not abnormally high on the first admission, and 4 years later the level was elevated as determined by the 30 gm arginine tolerance test. An alpha cell carcinoma detected in the tail of the pancreas was associated with a lymph node metastasis; the skin eruption cleared up 10 days after the partial pancreatectomy with lymphadenectomy. The clinical features of glucagonoma syndrome should be given attention.
authors.affiliation: Department of Dermatology, Saga Prefectural Hospital, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Hashizume
authors.forename: H
authors.initials: H
authors.lastname: Kiryu
authors.forename: K
authors.initials: K
authors.lastname: Noda
authors.forename: T
authors.initials: T
authors.lastname: Kano
authors.forename: R
authors.initials: R
authors.lastname: Nakano
mesh_terms: D007516:Adenoma, Islet Cell / Q000097:blood*; D001120:Arginine; D003951:Diagnostic Errors; D005934:Glucagon / Q000097:blood; D005935:Glucagonoma / Q000097:blood* / Q000150:complications / Q000473:pathology; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000097:blood* / Q000150:complications / Q000473:pathology; D012871:Skin Diseases / Q000175:diagnosis* / Q000209:etiology; D013577:Syndrome
chemical_list: D005934:Glucagon; D001120:Arginine