Polymorphism in mitochondrial DNA of several Trichophyton rubrum isolates from clinical specimens.
Mitochondrial DNA from six isolates of Trichophyton rubrum (a fungal pathogen of humans) was isolated, purified and digested by restriction endonucleases HindIII, HaeIII, AluI and EcoR1. The isolates could be classified into two groups according to their characteristic fragment patterns. Electron microscopy indicated that T. rubrum mitochondrial DNA are circular molecules of different lengths, 26.85 microns and 21.60 microns respectively, according to the group.
de Bièvre
C
C
Unité de Mycologie, Institut Pasteur, Paris.
Dauguet
C
C
Nguyen
V H
VH
Ibrahim-Granet
O
O
D004262:DNA Restriction Enzymes; D004270:DNA, Circular / Q000235:genetics / Q000302:isolation & purification; D004271:DNA, Fungal / Q000235:genetics* / Q000302:isolation & purification; D004272:DNA, Mitochondrial / Q000235:genetics* / Q000302:isolation & purification; D004587:Electrophoresis, Agar Gel; D008854:Microscopy, Electron; D011110:Polymorphism, Genetic; D014249:Trichophyton / Q000235:genetics*
D004270:DNA, Circular; D004271:DNA, Fungal; D004272:DNA, Mitochondrial; D004262:DNA Restriction Enzymes