title: [Problems of statistical evaluation of survival time studies].
abstract: When analyzing clinical studies where the survival time of the patients or, more generally, the time to a certain event in the patients' clinical course is the main endpoint, several problems have to be taken into account. Most of these problems, e.g. incomplete data and follow-up of the patients, arise specifically from the factor time which plays the central role in these studies. How such problems should be incorporated into a statistical analysis and into a sensible interpretation of the results is demonstrated by means of the estimation of survival rates with the Kaplan-Meier-method.
authors.affiliation: Institut für Medizinische Biometrik und Informatik, Universität Freiburg.
authors.forename: M
authors.initials: M
authors.lastname: Schumacher
mesh_terms: D001859:Bone Neoplasms / Q000401:mortality* / Q000601:surgery; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000401:mortality; D011183:Postoperative Complications / Q000401:mortality*; D012307:Risk Factors; D015983:Selection Bias; D016019:Survival Analysis
vernacular_title: Probleme der statistischen Auswertung von Uberlebenszeitstudien.