title: [Behavior of T1 relaxation time in normal and neoplastic pulmonary tissue. An in vitro study].
abstract: The aim of the study was to look for a difference between normal and neoplastic lung tissue by means of Magnetic Resonance Spectroscopy in vitro. A 2.1 Tesla intensity spectrometer was used. From 23 pneumonectomized patients, two samples from the lung were taken immediately after surgery: one from the center of the neoplasm, one from the healthy surrounding tissue; on each of them T1 relaxation time was measured. Twenty patients out of 23 had a higher T1 relaxation time in the pathologic tissue than in the healthy surrounding tissue; only in 3 cases the T1 of neoplastic tissue was lower than that of the healthy tissue. A correlation was also sought between the T1 value and the histologic type of the neoplasm. In epidermoid carcinoma, the T1 relaxation time increased with the malignity of the neoplasm.
authors.affiliation: Istituto di Radiologia, Università degli Studi, Padova.
authors.forename: A
authors.initials: A
authors.lastname: Tregnaghi
authors.forename: T
authors.initials: T
authors.lastname: Toffolutti
authors.forename: R
authors.initials: R
authors.lastname: Butini
authors.forename: B
authors.initials: B
authors.lastname: Riga
authors.forename: F
authors.initials: F
authors.lastname: Coletta
authors.forename: P C
authors.initials: PC
authors.lastname: Muzzio
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis*; D000368:Aged; D002276:Carcinoid Tumor / Q000175:diagnosis; D018288:Carcinoma, Small Cell / Q000175:diagnosis*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged
vernacular_title: Comportamento del tempo di rilassamento T1 nel tessuto polmonare normale e neoplastico. Studio in vitro.