title: Regulation of the Escherichia coli secA gene by protein secretion defects: analysis of secA, secB, secD, and secY mutants.
abstract: SecA protein synthesis levels were elevated 10- to 20-fold when protein secretion was blocked in secA, secD, and secY mutants or in a malE-lacZ fusion-containing strain but not in a secB null mutant. An active secB gene product was not required to derepress secA, since SecA levels were elevated during protein export blocks in secB secY and secB malE-lacZ double mutants.
authors.affiliation: Department of Microbiology, State University of New York, Stony Brook 11794-8621.
authors.forename: E E
authors.initials: EE
authors.lastname: Rollo
authors.forename: D B
authors.initials: DB
authors.lastname: Oliver
mesh_terms: D001426:Bacterial Proteins / Q000096:biosynthesis / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics*; D005786:Gene Expression Regulation; D009154:Mutation; D013696:Temperature
chemical_list: D001426:Bacterial Proteins