Gastrin, ACTH and STH after pylorus ligation and vagotomy in rats.
Plasma levels of gastrin, adrenocorticotropin (ACTH) and somatotropin (STH) were determined 24 hours after pylorus ligation and after pylorus ligation and vagotomy by radioimmunoassay. Pylorus ligation increases the serum levels of these hormones, while vagotomy inhibits the production of these ones. We conclude that the antiulcerogenetic effect of surgical vagotomy is closely related with the changes in the level of these hormones.
Sibul
U
U
Department of Surgery, Tartu State University, Estonia/USSR.
Miidla
I
I
Zilmer
M
M
D000324:Adrenocorticotropic Hormone / Q000097:blood*; D000818:Animals; D005755:Gastrins / Q000097:blood*; D013006:Growth Hormone / Q000097:blood*; D008026:Ligation; D008297:Male; D011708:Pylorus; D011863:Radioimmunoassay; D051381:Rats; D011919:Rats, Inbred Strains; D013270:Stomach / Q000502:physiology; D014628:Vagotomy
D005755:Gastrins; D000324:Adrenocorticotropic Hormone; D013006:Growth Hormone