title: The clinical manifestations and natural history of hepatocellular carcinoma.
abstract: Striking geographical differences occur in the clinical presentation of hepatocellular carcinoma in high and low incidence areas. This tumor is also associated with a number of paraneoplastic phenomena that may antedate the clinical appearance.
authors.affiliation: Liver Diseases Section, NIDDK, National Institute of Health, Bethesda, Maryland.
authors.forename: C
authors.initials: C
authors.lastname: Kassianides
authors.forename: M C
authors.initials: MC
authors.lastname: Kew
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000473:pathology*; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology; D006937:Hypercholesterolemia / Q000209:etiology; D007003:Hypoglycemia / Q000209:etiology; D008103:Liver Cirrhosis / Q000150:complications; D008113:Liver Neoplasms / Q000473:pathology*; D010257:Paraneoplastic Syndromes / Q000150:complications; D011086:Polycythemia / Q000209:etiology