title: Actinobacillus (Haemophilus) pleuropneumoniae infections in swine: serological investigations and vaccination trials in combination with environmental improvements.
abstract: The present investigation comprised six integrated herds (100-150 sows each) and one specialized fattening herd. Serologic tests by ELISA were performed on blood samples from piglets and growing pigs during various rearing phases in order to determine the presence of Actinobacillus infection and to estimate the age of the animals at onset of the disease. Using this information, herd-specific vaccination programs were designed against Actinobacillus pleuropneumoniae serotype 2. The weaned piglets in the integrated herds were vaccinated twice before being moved to the fattening unit. In the specialized fattening herd, the pigs were vaccinated on arrival at the growing unit and just before transfer to the finishing unit. The frequencies of chronic pleuritis at slaughter demonstrated that a vaccination program adapted to the herd-specific problem, in combination with environmental improvements, reduces the prevalence of chronic pleuritis. On the other hand, only a moderate reduction of the prevalence of chronic pleuritis occurred as a result of vaccination if no environmental improvements were made. In two of the herds during the vaccination period, the number of feeding days and food consumption decreased, while growth per day increased. There was also an apparent correlation between higher serum titres and a decreased prevalence of pleuritis at slaughter in three of the herds.
authors.forename: P
authors.initials: P
authors.lastname: Beskow
authors.forename: O
authors.initials: O
authors.lastname: Söderlind
authors.forename: B
authors.initials: B
authors.lastname: Thafvelin
mesh_terms: D000189:Actinobacillus Infections / Q000517:prevention & control / Q000662:veterinary*; D000818:Animals; D005260:Female; D010998:Pleurisy / Q000517:prevention & control / Q000662:veterinary*; D011001:Pleuropneumonia / Q000517:prevention & control / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000517:prevention & control*; D014611:Vaccination / Q000662:veterinary*