Integration of cellular-SV40 DNA and the thermal stability of the recombinant sites. Brief report.
We calculated the predicted melting profiles of evolutionary variants of SV40 and compared the nucleotide sequences of large T antigen binding sites and recombinant sites for homology. Neither is critically important in selecting a recombinant site for SV40-SV40 and SV40-cellular DNA fragments.
Rashid
K
K
Department of Biomathematics, University of Texas M. D. Anderson Hospital and Tumor Institute, Houston.
White
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RA
D000957:Antigens, Viral, Tumor / Q000378:metabolism; D001665:Binding Sites; D002472:Cell Transformation, Viral; D004252:DNA Mutational Analysis; D004279:DNA, Viral / Q000235:genetics*; D009693:Nucleic Acid Hybridization; D011995:Recombination, Genetic; D012689:Sequence Homology, Nucleic Acid; D013539:Simian virus 40 / Q000235:genetics*
D000957:Antigens, Viral, Tumor; D004279:DNA, Viral