title: A new human alphoid-like repetitive DNA sequence.
abstract: A new tandemly repetitive sequence family, having the 170 bp basic repeat characteristic of alphoid sequences, has been identified in the human genome. Its organization in the whole genome and on chromosome 21 is different from that of any of the previously described alphoid families. Members of this new family are unusually heterogeneous in sequence, and there are a number of variant sequence classes. Some of the variant classes exist in separate genomic domains, and even on a single chromosome the members of such a class are not significantly intermixed with members of another class.
authors.affiliation: Department of Biology, Loyola University of Chicago, IL 60626.
authors.forename: J L
authors.initials: JL
authors.lastname: Doering
authors.forename: A E
authors.initials: AE
authors.lastname: Burket
authors.forename: S L
authors.initials: SL
authors.lastname: Carnahan
mesh_terms: D002891:Chromosomes, Human, Pair 21; D004247:DNA / Q000235:genetics* / Q000302:isolation & purification; D004262:DNA Restriction Enzymes; D005260:Female; D005796:Genes; D014644:Genetic Variation; D006801:Humans; D010920:Placenta / Q000032:analysis; D011247:Pregnancy; D012091:Repetitive Sequences, Nucleic Acid
chemical_list: D004247:DNA; D004262:DNA Restriction Enzymes