Inhibition of antibody-dependent cell-mediated cytolysis of tumor cells by Fc receptor of human cytomegalovirus. Brief report.
The presence of HCMV-infected cells inhibits the killing of mouse tumor cells by adherent PEC in an antibody-dependent cell-mediated cytotoxicity (ADCC) test system. The effect of HCMV-infected cells on ADCC is mediated by the binding of IgG to the Fc receptors of infected cells.
Murayama
T
T
Department of Microbiology, Kanazawa Medical University, Ishikawa, Japan.
Shimokawa
K
K
Furukawa
T
T
D000920:Antibody-Dependent Cell Cytotoxicity; D003587:Cytomegalovirus / Q000276:immunology*; D003586:Cytomegalovirus Infections / Q000276:immunology*; D008264:Macrophages / Q000276:immunology; D009000:Monocytes / Q000276:immunology; D010529:Peritoneal Cavity / Q000166:cytology; D010844:Picibanil / Q000494:pharmacology; D011961:Receptors, Fc / Q000276:immunology*
D011961:Receptors, Fc; D010844:Picibanil