[Behavior of T1 relaxation time in normal and neoplastic pulmonary tissue. An in vitro study].
The aim of the study was to look for a difference between normal and neoplastic lung tissue by means of Magnetic Resonance Spectroscopy in vitro. A 2.1 Tesla intensity spectrometer was used. From 23 pneumonectomized patients, two samples from the lung were taken immediately after surgery: one from the center of the neoplasm, one from the healthy surrounding tissue; on each of them T1 relaxation time was measured. Twenty patients out of 23 had a higher T1 relaxation time in the pathologic tissue than in the healthy surrounding tissue; only in 3 cases the T1 of neoplastic tissue was lower than that of the healthy tissue. A correlation was also sought between the T1 value and the histologic type of the neoplasm. In epidermoid carcinoma, the T1 relaxation time increased with the malignity of the neoplasm.
Tregnaghi
A
A
Istituto di Radiologia, Università degli Studi, Padova.
Toffolutti
T
T
Butini
R
R
Riga
B
B
Coletta
F
F
Muzzio
P C
PC
D000230:Adenocarcinoma / Q000175:diagnosis*; D000368:Aged; D002276:Carcinoid Tumor / Q000175:diagnosis; D018288:Carcinoma, Small Cell / Q000175:diagnosis*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged
Comportamento del tempo di rilassamento T1 nel tessuto polmonare normale e neoplastico. Studio in vitro.