Beta-sympathomimetic agents: use in perinatal obstetrics.
Beta-sympathomimetic agents are used extensively in obstetrics to inhibit premature labor. Knowledge of the pharmacology, mode of action on smooth muscle, and cardiovascular and metabolic side effects of these agents is essential for the obstetrician and perinatologist. This review article draws extensively on recent animal research data to explain mechanisms of action and long-term effects of beta-sympathomimetic agents.
Nuwayhid
B
B
McGill University, Montreal, Canada.
Rajabi
M
M
D000818:Animals; D005260:Female; D005333:Fetus / Q000187:drug effects; D006801:Humans; D009215:Myometrium / Q000098:blood supply / Q000187:drug effects; D007752:Obstetric Labor, Premature / Q000517:prevention & control*; D011247:Pregnancy; D011943:Receptors, Adrenergic, beta / Q000378:metabolism; D013566:Sympathomimetics / Q000009:adverse effects / Q000493:pharmacokinetics / Q000494:pharmacology*; D014590:Uterine Contraction / Q000187:drug effects; D014592:Uterine Hemorrhage / Q000139:chemically induced
D011943:Receptors, Adrenergic, beta; D013566:Sympathomimetics