[The effect of the alimentary factor on erythrocyte ATPase activity in ischemic heart disease patients].
Functional disorders in the ion-transport ATPase system were detected in young and middle-aged males suffering from coronary heart disease (CHD). The degree of the ATPase activity impairment (general ATPase, Mg-ATPase and Na, K-ATPase) correlated with hyperlipoproteinemia (HLP) which was revealed in CHD patients. Different direction of changes was observed in the concentrations of cations in plasma and erythrocytes, that, in some cases, could not be correlated with the degree of HLP and suppression of ion-transport ATPase activity. Positive correlation was observed with respect to increased concentration of Mg2+ in serum and Na+ in erythrocytes, and hypercholesterolemia, as well as with respect to decreased concentration of Mg2+, suppressed Mg-ATPase activity, and hypo-alpha-cholesterolemia. A significant tendency to normalization of parameters of lipid metabolism and lipid-dependent ion-transport ATPases was recorded in CHD patients after a course of the anti-atherosclerotic dietotherapy.
Samsonov
M A
MA
Tsagikian
T A
TA
Meshcheriakova
V A
VA
Frolova
I A
IA
D000251:Adenosine Triphosphatases / Q000097:blood*; D000328:Adult; D001161:Arteriosclerosis / Q000517:prevention & control; D017301:Ca(2+) Mg(2+)-ATPase / Q000097:blood; D002908:Chronic Disease; D003327:Coronary Disease / Q000178:diet therapy* / Q000201:enzymology; D004912:Erythrocytes / Q000201:enzymology*; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D000254:Sodium-Potassium-Exchanging ATPase / Q000097:blood
D008055:Lipids; D000251:Adenosine Triphosphatases; D017301:Ca(2+) Mg(2+)-ATPase; D000254:Sodium-Potassium-Exchanging ATPase
K voprosu o vliianii alimentarnogo faktora na ATF-aznuiu aktivnost' éritrotsitov u bol'nykh ishemicheskoĭ bolezn'iu serdtsa.