title: [Isolation of viruses in the cerebrospinal fluid in a case of acute varicella meningo-encephalitis].
abstract: The authors report a case of severe, life-threatening, meningo-encephalitis occurring in a young nonimmunodepressed adult with varicella. The demonstration of a cytopathogenetic effect of his cerebrospinal fluid and of immunoglobulins M specific to the varicella-zoster virus was in favour of an acute, directly viral-dependent encephalitis rather than an immune-mediated leucoencephalitis, as used to be commonly admitted. This is an incitement to use acyclovir in such cases, the effect of which contributes to reinforce this pathogenic hypothesis.
authors.forename: G
authors.initials: G
authors.lastname: Auzanneau
authors.forename: A
authors.initials: A
authors.lastname: Chagnon
authors.forename: M
authors.initials: M
authors.lastname: Morillon
authors.forename: M
authors.initials: M
authors.lastname: Verdier
authors.forename: J P
authors.initials: JP
authors.lastname: de Jaureguiberry
mesh_terms: D000328:Adult; D002644:Chickenpox / Q000150:complications; D014645:Herpesvirus 3, Human / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008590:Meningoencephalitis / Q000134:cerebrospinal fluid* / Q000209:etiology / Q000382:microbiology
vernacular_title: Isolement du virus dans le liquide céphalo-rachidien dans un cas de méningo-encéphalite aiguë de la varicelle.