title: Comparison of naturally occurring poliovirus-reactive immunoglobulins in bovine and equine sera.
abstract: Bovine and equine sera were screened for poliovirus-reactive immunoglobulins (PRIgs) by means of neutralization and precipitation reactions with type 1 poliovirus. Bovine serum B1826 and B36 were found to contain such PRIgs from their reactivity to various PRIgs-resistant mutants of type 1 poliovirus origin. Neutralization and precipitation reactions with six mono-specific antibodies obtained by absorbing antiserum with each of the six different PRIgs-resistant virus mutants revealed that three antibodies were active in precipitation reaction while the others were substantially ineffective. On the basis of the results obtained and the findings reported to date, the mechanism of production of PRIgs in bovine and equine sera was discussed.
authors.affiliation: Department of Hygiene and Epidemiology, Sapporo Medical College, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Urasawa
authors.forename: T
authors.initials: T
authors.lastname: Urasawa
authors.forename: F
authors.initials: F
authors.lastname: Ishizawa
authors.forename: K
authors.initials: K
authors.lastname: Taniguchi
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000302:isolation & purification*; D000918:Antibody Specificity; D002417:Cattle / Q000276:immunology*; D011232:Chemical Precipitation; D006736:Horses / Q000276:immunology*; D007113:Immunity, Innate; D007136:Immunoglobulins / Q000302:isolation & purification; D009154:Mutation; D009500:Neutralization Tests; D017955:Poliovirus / Q000235:genetics / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D007136:Immunoglobulins