Estrogen-secreting adrenal tumor responsive to ACTH: localization by adrenal venous sampling.
In a 48-year-old man with gynecomastia but no other signs of feminization, routine evaluation revealed only minimally elevated serum estrogens. The diagnosis of an estrogen-secreting adrenal tumor was suggested by CT and confirmed by adrenal venous sampling. This tumor was found to be ACTH-responsive. Results in this patient are compared with those in normal volunteers, in whom adrenal venous sampling failed to localize estrogen secretion and in whom ACTH did not increase estrogens.
Mersey
J H
JH
Department of Medicine, Veterans Administration Medical Center, Baltimore, MD 21218.
Ceballos
L
L
Levin
P
P
Busky
S
S
D000306:Adrenal Cortex Neoplasms / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000378:metabolism*; D000311:Adrenal Glands / Q000098:blood supply; D000324:Adrenocorticotropic Hormone; D004958:Estradiol / Q000378:metabolism; D004967:Estrogens / Q000097:blood / Q000378:metabolism*; D004970:Estrone / Q000378:metabolism; D005262:Feminization / Q000209:etiology*; D006391:Hemangioma / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000378:metabolism; D006729:Hormones, Ectopic / Q000097:blood / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D014680:Veins
D004967:Estrogens; D006729:Hormones, Ectopic; D004970:Estrone; D004958:Estradiol; D000324:Adrenocorticotropic Hormone