title: [Ultrasonic medicinal aerosols in multimodal treatment of acute surgical diseases of the organs of the abdominal cavity].
abstract: Microbiologic studies have shown that ultrasonic aerosol treatment of E. coli reference culture with 0.02% furacillin solution for 3 min reduces its survival rate by 2 orders (240-fold). Exposure to low-energy ultrasound increases 7-fold the antibacterial activity of furacillin solution. Experiments have demonstrated that 99mTc ionized particles diffusion via cadaver peritoneum is enhanced more than 5 times if Tc solution is spread via ultrasonic aerosol. A method for ultrasonic aerosol treatment of infected abdominal cavity has been developed. Clinical trials of the method have been carried out: it has been employed in multiple-modality treatment of acute surgical diseases of the abdominal organs in 6 patients and of postoperative peritonitis in 15 patients, as well as for the prevention of purulent complications after extensive abdominal surgery in 4 patients.
authors.forename: I S
authors.initials: IS
authors.lastname: Gadzhiev
mesh_terms: D000006:Abdomen, Acute / Q000601:surgery / Q000628:therapy*; D000293:Adolescent; D000328:Adult; D000336:Aerosols / Q000008:administration & dosage*; D000368:Aged; D003131:Combined Modality Therapy; D006801:Humans; D008875:Middle Aged; D009583:Nitrofurazone / Q000008:administration & dosage*; D010538:Peritonitis / Q000628:therapy; D011183:Postoperative Complications / Q000628:therapy; D014464:Ultrasonic Therapy
chemical_list: D000336:Aerosols; D009583:Nitrofurazone
vernacular_title: Ul'trazvukovye lekarstvennye aérozoli v kompleksnom lechenii ostrykh khirurgicheskikh zabolevaniĭ organov briushnoĭ polosti.