title: [Quantitative CT studies of the lung in an animal experiment model of silicosis].
abstract: High resolution, narrow section CT examinations of the lungs were carried out on 21 Javanese macaques (five controls) shortly before the conclusion of 27 months exposure to quartz and/or high pressure. The aim was to establish morphometric CT data for differentiating and quantifying normal and abnormal findings. The results show that the technique has a high sensitivity for demonstrating the pathological lung changes. Final validation depends upon the use of respiratory physiology and biochemical, cytological, and histomorphometric data.
authors.affiliation: Radiologische Klinik und Poliklinik, Universität München, Klinikum Grosshadern.
authors.forename: R
authors.initials: R
authors.lastname: Rienmüller
authors.forename: M
authors.initials: M
authors.lastname: Schätzl
authors.forename: W
authors.initials: W
authors.lastname: Kalender
authors.forename: F
authors.initials: F
authors.lastname: Krombach
authors.forename: E
authors.initials: E
authors.lastname: Fiehl
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D008168:Lung / Q000000981:diagnostic imaging*; D008252:Macaca fascicularis; D012829:Silicosis / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
vernacular_title: Quantitative CT-Untersuchungen der Lunge am tierexperimentellen Modell der Silikose.