[Study of the encapsulation and transport of several proteins to different organs by means of liposomal type particles of viral origin].
Liposomal particles may be more efficiently incorporated by cells through mechanisms still incompletely elucidated. This property allowed to use them as a vehicle for macromolecules. Research was conducted to obtain liposomal type particles of viral origin charged with various proteins (bovine serum albumin, ovalbumin, ribosomes, human 125I-immunoglobulin G) and to establish the distribution of proteins encapsulated in viral envelopes among various organs after inoculation to laboratory animals.
Repanovici
R
R
Institut de Virologie, Stefan S. Nicolau, Bucarest, Roumanie.
Iliescu
R
R
Popa
L M
LM
D000818:Animals; D002642:Chick Embryo; D004591:Electrophoresis, Polyacrylamide Gel; D007074:Immunoglobulin G / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008081:Liposomes / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D051379:Mice; D008854:Microscopy, Electron; D010047:Ovalbumin / Q000378:metabolism; D010222:Parainfluenza Virus 1, Human; D012270:Ribosomes / Q000378:metabolism; D012710:Serum Albumin, Bovine / Q000378:metabolism
D007074:Immunoglobulin G; D008081:Liposomes; D012710:Serum Albumin, Bovine; D010047:Ovalbumin
Recherches sur l'encapsulation et le transport de quelques protéines vers différents organes par l'intermédiaire de particules du type liposomal d'origine virale.