title: Eczema herpeticum. Clinical and laboratory features.
abstract: Eczema herpeticum (EH) is a potentially life-threatening complication that may occur in children with atopic dermatitis. The clinical and laboratory features of EH as seen in 14 children are reported. The mean age of affected children was 34 months. A rapid viral diagnosis was made in 72 percent of patients. In one-third of patients there was a history of herpes labialis in one or other parent in the previous week. In 28 percent of the children, EH was initially thought to be an exacerbation or impetiginization of the underlying dermatitis. Eleven of 14 children were treated with acyclovir (intravenously in eight, orally in three). All patients recovered without sequelae.
authors.affiliation: Department of Infectious Diseases, Hospital for Sick Children, London, England.
authors.forename: V M
authors.initials: VM
authors.lastname: Novelli
authors.forename: D J
authors.initials: DJ
authors.lastname: Atherton
authors.forename: W C
authors.initials: WC
authors.lastname: Marshall
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000150:complications; D005260:Female; D006560:Herpes Labialis / Q000150:complications; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007617:Kaposi Varicelliform Eruption / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D008297:Male; D018139:Simplexvirus / Q000302:isolation & purification
chemical_list: D000212:Acyclovir