The nucleotide sequence of human rhinovirus 1B: molecular relationships within the rhinovirus genus.
We have determined the complete nucleotide sequence of human rhinovirus 1B and made comparisons with other rhinoviruses. Extensive homology was found with serotypes 2 and 89 but the similarity to serotype 14 was considerably less. Rhinovirus-specific characteristics have been noted, in particular the length of the 5' non-coding region and the pattern of codon usage, and these may be sufficient to define the rhinoviruses as a distinct genus rather than being considered as members of the enteroviruses as has been suggested previously.
Hughes
P J
PJ
Department of Biology, University of Essex, Colchester, U.K.
North
C
C
Jellis
C H
CH
Minor
P D
PD
Stanway
G
G
D000595:Amino Acid Sequence; D001483:Base Sequence; D003001:Cloning, Molecular; D003062:Codon / Q000235:genetics; D004247:DNA / Q000235:genetics; D004770:Enterovirus / Q000235:genetics; D005814:Genes, Viral; D006801:Humans; D008969:Molecular Sequence Data; D012367:RNA, Viral / Q000235:genetics*; D012229:Rhinovirus / Q000145:classification / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D014764:Viral Proteins / Q000235:genetics*
D003062:Codon; D012367:RNA, Viral; D014764:Viral Proteins; D004247:DNA