HTLV-I-like viral particles in spinal cord cells in Jamaican tropical spastic paraparesis.
Viral-like particles morphologically identical to human T-lymphotropic virus type I or II, but distinct from human T-lymphotropic virus type III, have been seen by electron microscopy in spinal cord tissue from a Jamaican tropical spastic paraparesis patient who was known to be positive for human T-lymphotropic virus I antibody before death. This is the first electron microscopy report on a patient from an endemic tropical spastic paraparesis region.
Liberski
P P
PP
Laboratory of Central Nervous System Studies, National Institute of Neurological and Communicative Disorders and Stroke, Bethesda, MD 20892.
Rodgers-Johnson
P
P
Char
G
G
Piccardo
P
P
Gibbs
C J
CJ
Gajdusek
D C
DC
D000328:Adult; D017977:Deltaretrovirus / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D007563:Jamaica; D008854:Microscopy, Electron; D009128:Muscle Spasticity / Q000382:microbiology / Q000473:pathology; D010264:Paraplegia / Q000382:microbiology* / Q000473:pathology; D013116:Spinal Cord / Q000382:microbiology* / Q000473:pathology; D014329:Tropical Climate