[Immunoscintigraphy in experiments and clinical practice: its possibilities, advantages and limitations].
The authors present their experience gained in preparing, isolating and labeling antibodies with radionuclides for the purpose of using them in immunoscintigraphy. The experimental part includes results obtained with different labeled antibodies and their F/ab/2 fragments in distribution studies, involving also immunoscintigraphic imaging of tumors. The clinical part presents results of immunoscintigraphy obtained with the commercial antibody kits Iodomab and Imacis in patients with tumors of the digestive tract.
Svihovcová
P
P
Koprivová
H
H
Novák
F
F
Dvorák
P
P
Poucková
P
P
Pospísil
J
J
Seblová
J
J
Dienstbier
Z
Z
Micheel
B
B
Jantscheff
P
P
D000818:Animals; D000911:Antibodies, Monoclonal; D005770:Gastrointestinal Neoplasms / Q000000981:diagnostic imaging*; D006801:Humans; D007457:Iodine Radioisotopes; D051379:Mice; D008815:Mice, Inbred Strains; D009368:Neoplasm Transplantation; D011877:Radionuclide Imaging
D000911:Antibodies, Monoclonal; D007457:Iodine Radioisotopes
Imunoscintigrafie v experimentu, klinice, její moznosti, výhody a omezení.