title: Synovial fluid hydroxyapatite crystals: detection thresholds of two methods.
abstract: A method of synovial fluid preparation giving optimal hydroxyapatite detection as well as definitions of the threshold masses of hydroxyapatite in viscous synovial fluid detectable by x ray diffraction and scanning electron microscopy with energy dispersive analysis is reported. Use of an equal volume of 100% hydrazine with the synovial fluid optimised detection of hydroxyapatite. By x ray diffraction the threshold mass of hydroxyapatite was 500 micrograms and by scanning electron microscopy with associated energy dispersive analysis 5 micrograms.
authors.affiliation: Division of Rheumatology, Hôpital Cantonal Universitaire, Geneva, Switzerland.
authors.forename: T
authors.initials: T
authors.lastname: Cunningham
authors.forename: D
authors.initials: D
authors.lastname: Uebelhart
authors.forename: J M
authors.initials: JM
authors.lastname: Very
authors.forename: G H
authors.initials: GH
authors.lastname: Fallet
authors.forename: T L
authors.initials: TL
authors.lastname: Vischer
mesh_terms: D002498:Centrifugation; D006801:Humans; D006882:Hydroxyapatites / Q000032:analysis*; D008855:Microscopy, Electron, Scanning; D013582:Synovial Fluid / Q000032:analysis*; D014961:X-Ray Diffraction
chemical_list: D006882:Hydroxyapatites