Allergic rhinitis relieved by aspirin and other nonsteroidal antinflammatory drugs.
Aspirin and other non-steroidal antiinflammatory drugs (NSAIDS) are known to cause urticaria and aggravate symptoms of bronchial asthma. This report describes a patient with allergic rhinitis whose symptoms were improved after ingestion of aspirin and the NSAIDS. The beneficial effect was confirmed by oral double-blind challenges.
Kumar
P
P
Department of Medicine, Louisiana State University School of Medicine.
Bryan
C
C
Hwang
D
D
Kadowitz
P
P
Butcher
B
B
Leech
S H
SH
D000284:Administration, Oral; D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D001241:Aspirin / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D000242:Cyclic AMP / Q000096:biosynthesis; D004311:Double-Blind Method; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D008297:Male; D009297:Nasal Mucosa / Q000032:analysis / Q000378:metabolism; D010974:Platelet Aggregation / Q000187:drug effects; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy*; D050378:T-Lymphocytes, Regulatory / Q000187:drug effects / Q000502:physiology; D013931:Thromboxanes / Q000032:analysis
D000894:Anti-Inflammatory Agents, Non-Steroidal; D013931:Thromboxanes; D007073:Immunoglobulin E; D000242:Cyclic AMP; D001241:Aspirin