Increased expression of novel full-length endogenous mink cell focus-forming-related transcripts in autoimmune mouse strains.
We have identified a novel 8.4-kb retroviral transcript which represents an endogenous mink cell focus-forming env-related provirus containing a 190-bp cellular DNA insert in the LTR region. This RNA species was highly expressed in tissues of autoimmune mouse strains, but not in those of nonautoimmune strains.
Krieg
A M
AM
Cellular Immunology Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, Maryland 20892.
Steinberg
A D
AD
Khan
A S
AS
D000818:Animals; D001327:Autoimmune Diseases / Q000382:microbiology*; D005786:Gene Expression Regulation; D009052:Leukemia Virus, Murine / Q000235:genetics*; D051379:Mice; D008815:Mice, Inbred Strains; D012333:RNA, Messenger / Q000235:genetics; D014158:Transcription, Genetic; D014759:Viral Envelope Proteins / Q000235:genetics
D012333:RNA, Messenger; D014759:Viral Envelope Proteins