title: Response to sodium lactate infusion in alcoholics with panic attacks.
abstract: The authors studied the response to sodium lactate infusion of 12 alcoholics with a history of panic attacks, 10 alcoholics without a history of panic attacks, and 16 nonalcoholic patients with panic disorder. The rate of lactate-induced panic was significantly higher in alcoholics with panic attacks than in alcoholics without panic attacks. Alcoholics with panic attacks were similar to nonalcoholic patients with panic disorder in their response to lactate. These findings support the specificity of lactate-induced panic for panic states and suggest that panic attacks in alcoholics resemble those in nonalcoholics. Lactate infusion may prove useful in the diagnosis of panic disorder in alcoholics.
authors.affiliation: Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle 98195.
authors.forename: D S
authors.initials: DS
authors.lastname: Cowley
authors.forename: C F
authors.initials: CF
authors.lastname: Jensen
authors.forename: D
authors.initials: D
authors.lastname: Johannessen
authors.forename: L
authors.initials: L
authors.lastname: Parker
authors.forename: S R
authors.initials: SR
authors.lastname: Dager
authors.forename: R D
authors.initials: RD
authors.lastname: Walker
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000150:complications*; D001008:Anxiety Disorders / Q000150:complications / Q000175:diagnosis*; D005239:Fear; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007773:Lactates; D019344:Lactic Acid; D008297:Male; D008875:Middle Aged; D010200:Panic / Q000187:drug effects*
chemical_list: D007773:Lactates; D019344:Lactic Acid