Viruses and antibody deficiency syndromes.
Viral infections that occur in patients with primary immunodeficiencies are summarized. These viral infections include: Echovirus, poliovirus, varicella zoster, non-A non-B hepatitis and hepatitis B. Cases of X-linked lymphoproliferative syndrome associated with Epstein-Barr virus infection and congenital rubella syndrome are also reviewed. In the second part of the paper, retrovirus (HIV) isolations from blood mononuclear cells of 3 out of 31 patients with common variable hypogammaglobulinemia are reported. This supports the concept that some of the non-familial "primary" immunodeficiencies may be due to retrovirus infections.
Webster
A D
AD
Division of Immunological Medicine, Clinical Research Centre, Harrow, Middlesex, U.K.
Spickett
G P
GP
Thomson
B J
BJ
Farrant
J
J
D000361:Agammaglobulinemia / Q000382:microbiology*; D004457:Echovirus Infections / Q000150:complications; D006525:Hepatitis, Viral, Human / Q000150:complications; D006801:Humans; D009894:Opportunistic Infections / Q000150:complications; D012192:Retroviridae Infections / Q000150:complications; D014777:Virus Diseases / Q000150:complications*