title: [Photodynamic laser tumor therapy with a hematoporphyrin derivative in spinocellular carcinoma of the external ear].
abstract: Haematoporphyrine-derivative (hpd) selectively photosensitises malignant tumours following intravenous application. 48 hours after injection of hpd an integral laser-light application of the tumour and the surrounding normal tissue was performed. We report on the successful administration of this photodynamic therapy in a patient with a spinocellular carcinoma of the auricle. 16 days after therapy the tumour showed a complete response without damage of the also irradiated surrounding normal tissue. Apart from a temporary sensitivity to light no side effects of the therapy were seen.
authors.affiliation: Klinik und Poliklinik für Hals-, Nasen-Ohrenheilkunde, Klinikum Grosshadern, Ludwig-Maximilians-Universität München.
authors.forename: J
authors.initials: J
authors.lastname: Feyh
authors.forename: A
authors.initials: A
authors.lastname: Goetz
authors.forename: F
authors.initials: F
authors.lastname: Martin
authors.forename: W
authors.initials: W
authors.lastname: Lumper
authors.forename: W
authors.initials: W
authors.lastname: Müller
authors.forename: W
authors.initials: W
authors.lastname: Brendel
authors.forename: E
authors.initials: E
authors.lastname: Kastenbauer
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000188:drug therapy*; D004428:Ear Neoplasms / Q000188:drug therapy*; D004431:Ear, External / Q000187:drug effects; D005500:Follow-Up Studies; D006414:Hematoporphyrin Photoradiation; D006801:Humans; D008297:Male; D008875:Middle Aged; D010778:Photochemotherapy
vernacular_title: Photodynamische Lasertumortherapie mit Hämatoporphyrin-Derivat (HpD) eines Spinozellulären Karzinomes der Ohrmuschel.