Effect of embryonic and neonatal administration of tamoxifen on adiposity in the broiler chicken.
1. The effect of early exposure of heavy breed (HB) chicks to an anti-oestrogen (tamoxifen--TAM) on later adiposity was studied. 2. TAM administration at the embryonic stage, but not at the day of hatching, reduced adiposity in females but not in males, at 8 to 9 weeks of age. This reduction in adiposity in females minimised or even alleviated the excess of fat in females compared to males.
Rozenboim
I
I
Department of Animal Science, Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel.
Robinzon
B
B
Arnon
E
E
Snapir
N
N
D000273:Adipose Tissue / Q000187:drug effects / Q000254:growth & development*; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002642:Chick Embryo / Q000187:drug effects* / Q000254:growth & development; D002645:Chickens / Q000254:growth & development*; D005260:Female; D008297:Male; D009929:Organ Size / Q000187:drug effects; D012737:Sex Factors; D013629:Tamoxifen / Q000494:pharmacology*
D013629:Tamoxifen