title: [Effect of drugs on superoxide formation by neutrophilic granulocytes].
abstract: The in-vitro influence of drugs on the superoxide production of human neutrophils was investigated. The superoxide production is inhibited by colchicine, g-strophanthin, propranolol, fluphenazine and stimulated by levamisole and lithium. The superoxide production is inhibited or stimulated by chloramphenicol, hydrocortisone and amphotericin B in concentration dependent manner.
authors.affiliation: Institut für Medizinische Mikrobiologie, Medizinischen Akademie Magdeburg.
authors.forename: D
authors.initials: D
authors.lastname: Schmidt
authors.forename: E
authors.initials: E
authors.lastname: Morenz
authors.forename: J
authors.initials: J
authors.lastname: Morenz
mesh_terms: D000666:Amphotericin B / Q000494:pharmacology; D002701:Chloramphenicol / Q000494:pharmacology; D003078:Colchicine / Q000494:pharmacology; D005476:Fluphenazine / Q000494:pharmacology; D006801:Humans; D006854:Hydrocortisone / Q000494:pharmacology; D007978:Levamisole / Q000494:pharmacology; D008094:Lithium / Q000494:pharmacology; D016651:Lithium Carbonate; D009504:Neutrophils / Q000187:drug effects*; D010042:Ouabain / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D013481:Superoxides / Q000378:metabolism*
chemical_list: D013481:Superoxides; D007978:Levamisole; D016651:Lithium Carbonate; D010042:Ouabain; D002701:Chloramphenicol; D000666:Amphotericin B; D008094:Lithium; D011433:Propranolol; D005476:Fluphenazine; D003078:Colchicine; D006854:Hydrocortisone
vernacular_title: Einfluss von Arzneimitteln auf die Superoxidbildung der neutrophilen Granulozyten.