title: Subgroups, serotypes, and electrophoretypes of rotavirus isolated from children in Bangui, Central African Republic.
abstract: The subgroups and serotypes of 178 strains of rotavirus isolated from diarrheic and healthy children in Bangui, Central African Republic, during a 27-month period were determined by enzyme-linked immunosorbent assay. The subgroup was determined for 152 of the viral strains, 18.4% being subgroup I and 81.6% being subgroup II. Of the 143 strains which could be serotyped, 71.3% were serotype 1, 15.4% were serotype 2, and 13.3% were serotype 3. Serotypes 1 and 3 were detected throughout the study, while serotype 2 was detected only during 8 months. No serotype exhibited any special epidemiological properties. The serotypes were found to consist of three different electrophoretypes, two long ones (A and B) and a short one (C). All subgroup I, serotype 2 strains presented short electrophoretypes. Strains with identical long electrophoretypes A were either serotype 1 or serotype 3.
authors.affiliation: Institut Pasteur, Bangui, Central African Republic.
authors.forename: M C
authors.initials: MC
authors.lastname: Georges-Courbot
authors.forename: A M
authors.initials: AM
authors.lastname: Beraud
authors.forename: G M
authors.initials: GM
authors.lastname: Beards
authors.forename: A D
authors.initials: AD
authors.lastname: Campbell
authors.forename: J P
authors.initials: JP
authors.lastname: Gonzalez
authors.forename: A J
authors.initials: AJ
authors.lastname: Georges
authors.forename: T H
authors.initials: TH
authors.lastname: Flewett
mesh_terms: D002488:Central African Republic; D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology / Q000382:microbiology*; D004591:Electrophoresis, Polyacrylamide Gel; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D012367:RNA, Viral / Q000032:analysis; D012401:Rotavirus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D012400:Rotavirus Infections / Q000453:epidemiology / Q000382:microbiology*; D012703:Serotyping
chemical_list: D012367:RNA, Viral