A second catalytic subunit of type-2A protein phosphatase from rabbit skeletal muscle.
A cDNA clone encoding a second type-2A protein phosphatase catalytic subunit (2A beta) was isolated from a rabbit skeletal muscle cDNA library constructed in lambda gt10. The deduced protein sequence (309 residues, 35.59 kDa) was 97% identical to that of phosphatase 2A alpha (309 residues, 35.58 kDa). At the nucleotide level, the two clones showed only 82% identity in the coding region. The results indicate the presence of at least two isoforms of protein phosphatase 2A in skeletal muscle.
da Cruz e Silva
O B
OB
Department of Biochemistry, University of Dundee, Scotland.
Cohen
P T
PT
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000302:isolation & purification; D008969:Molecular Sequence Data; D009132:Muscles / Q000201:enzymology*; D010749:Phosphoprotein Phosphatases / Q000235:genetics*; D054648:Protein Phosphatase 2; D011817:Rabbits
D004247:DNA; D010749:Phosphoprotein Phosphatases; D054648:Protein Phosphatase 2