title: Software for genome mapping by fingerprinting techniques.
abstract: A genome mapping package has been developed for reading and assembling data from clones analysed by restriction enzyme fragmentation and polyacrylamide gel electrophoresis. The package comprises: data entry; matching; assembly; statistical analysis; modelling. Data entry can be either manual or by a semiautomatic system based on a scanning densitometer. The primary emphasis in the analytical routines is on flexibility and interactive convenience, so that the operator has full knowledge of and control over the growing map, but a variety of automatic options are included. The package continually grows to meet the needs of the Caenorhabditis project.
authors.affiliation: MRC Laboratory of Molecular Biology, Cambridge, UK.
authors.forename: J
authors.initials: J
authors.lastname: Sulston
authors.forename: F
authors.initials: F
authors.lastname: Mallett
authors.forename: R
authors.initials: R
authors.lastname: Staden
authors.forename: R
authors.initials: R
authors.lastname: Durbin
authors.forename: T
authors.initials: T
authors.lastname: Horsnell
authors.forename: A
authors.initials: A
authors.lastname: Coulson
mesh_terms: D001483:Base Sequence; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics / Q000302:isolation & purification; D004262:DNA Restriction Enzymes; D003628:Database Management Systems; D004591:Electrophoresis, Polyacrylamide Gel; D012984:Software
chemical_list: D004247:DNA; D004262:DNA Restriction Enzymes