title: Effect of flunitrazepam (Rohypnol) on awareness during anaesthesia for caesarean section.
abstract: The incidence of awareness was compared in three groups of patients undergoing elective or emergency Caesarean section, using pethidine alone or pethidine plus flunitrazepam (Rohypnol), as adjuvants to nitrous oxide: oxygen, muscle relaxant technique of general anaesthesia. The use of 0.03 mg/kg body weight of flunitrazepam was associated with a low incidence (4%) of awareness, cardiovascular stability, postoperative sedation and anterograde amnesia. The reduced incidence of awareness is probably due to increased depth of anaesthesia and anterograde amnesic effect produced by the drug.
authors.affiliation: Department of Anaesthesia, University College Hospital, Ibadan, Nigeria.
authors.forename: O A
authors.initials: OA
authors.lastname: Soyannwo
authors.forename: E O
authors.initials: EO
authors.lastname: Elegbe
authors.forename: C O
authors.initials: CO
authors.lastname: Odugbesan
mesh_terms: D000328:Adult; D000769:Anesthesia, Inhalation; D000773:Anesthesia, Obstetrical; D001364:Awareness / Q000187:drug effects*; D002585:Cesarean Section; D003071:Cognition / Q000187:drug effects*; D005260:Female; D005445:Flunitrazepam / Q000494:pharmacology*; D006801:Humans; D008614:Meperidine / Q000494:pharmacology; D011247:Pregnancy
chemical_list: D005445:Flunitrazepam; D008614:Meperidine