title: (+/-)-4-tert-butyl-3-cyano-1-(4-ethynylphenyl)-2,6,7-trioxabi cyclo[2.2.2]octane: synthesis of a remarkably potent GABAA receptor antagonist.
authors.affiliation: Department of Entomological Sciences, University of California, Berkeley 94720.
authors.forename: C J
authors.initials: CJ
authors.lastname: Palmer
authors.forename: L M
authors.initials: LM
authors.lastname: Cole
authors.forename: J E
authors.initials: JE
authors.lastname: Carida
mesh_terms: D000818:Animals; D001643:Bridged Bicyclo Compounds / Q000378:metabolism; D019086:Bridged Bicyclo Compounds, Heterocyclic; D002712:Chlorides / Q000378:metabolism; D003292:Convulsants / Q000138:chemical synthesis* / Q000494:pharmacology; D018756:GABA Antagonists; D051379:Mice; D051381:Rats; D011963:Receptors, GABA-A / Q000187:drug effects*
chemical_list: D001643:Bridged Bicyclo Compounds; D019086:Bridged Bicyclo Compounds, Heterocyclic; D002712:Chlorides; D003292:Convulsants; D018756:GABA Antagonists; D011963:Receptors, GABA-A; C037476:tert-butylbicyclophosphorothionate