Ovarian neoplasia in the Sprague-Dawley rat.
Macroscopic and microscopic characteristics of 210 spontaneous ovarian tumors from 7748 Sprague-Dawley rats are described. The tumors were classified as tubular adenoma, anaplastic adenocarcinoma, papillary cystadenoma, papillary cystadenocarcinoma, mesothelioma, sertoliform tubular adenoma, Sertoli's cell tumor, granulosa cell tumor, thecal cell tumor, polycystic sex cord/stromal tumor, and lipoid cell tumor. The histogenesis of the tumor types is discussed.
Lewis
D J
DJ
Department of Pathology, Huntingdon Research Centre, Cambridgeshire, England.
D000230:Adenocarcinoma / Q000473:pathology; D000236:Adenoma / Q000473:pathology; D000818:Animals; D003536:Cystadenocarcinoma / Q000473:pathology; D003537:Cystadenoma / Q000473:pathology; D005260:Female; D006106:Granulosa Cell Tumor / Q000473:pathology; D008654:Mesothelioma / Q000473:pathology; D010051:Ovarian Neoplasms / Q000145:classification / Q000473:pathology*; D051381:Rats; D011919:Rats, Inbred Strains; D012707:Sertoli Cell Tumor / Q000473:pathology; D013798:Thecoma / Q000473:pathology