Prophylaxis and therapy of virulent encephalomyocarditis virus infection in mice by monoclonal antibodies. Brief report.
Two encephalomyocarditis virus (EMCV) neutralizing monoclonal antibodies (MAs), recognizing different determinants on EMCV, were both able to protect mice prophylactically and therapeutically against a lethal dose of EMCV.
Vlaspolder
F
F
Laboratory of Microbiology, State University of Utrecht, The Netherlands.
Kraaijeveld
C A
CA
van Buuren
R
R
Harmsen
M
M
Benaissa-Trouw
B J
BJ
Snippe
H
H
D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D000914:Antibodies, Viral / Q000627:therapeutic use*; D004686:Encephalomyocarditis virus / Q000276:immunology*; D004769:Enterovirus Infections / Q000276:immunology / Q000517:prevention & control* / Q000628:therapy; D007116:Immunization, Passive; D007167:Immunotherapy; D007739:L Cells; D051379:Mice; D008807:Mice, Inbred BALB C
D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral