Heat shock-induced accumulation of ubiquitin mRNA in Xenopus laevis embryos is developmentally regulated.
Exposure of Xenopus laevis embryos to heat shock induced the accumulation of ubiquitin mRNA (size range, 1.7-3.5 kb) in a developmental stage-dependent fashion. While constitutive ubiquitin transcripts were detectable throughout development, heat shock-induced accumulation did not occur until the fine-cell blastula stage. Continuous exposure of neurulae to heat shock (33 degrees C) induced a transient accumulation of ubiquitin mRNA with peak levels occurring after 2 hr. Finally, placement of Xenopus neurulae at 22 degrees C after a 1-hr heat shock at 33 degrees C produced a decrease in ubiquitin mRNA levels to near control levels by 24 hr.
Ovsenek
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N
Department of Biology, University of Waterloo, Ontario, Canada.
Heikkila
J J
JJ
D000818:Animals; D004625:Embryo, Nonmammalian / Q000378:metabolism; D005786:Gene Expression Regulation; D006358:Hot Temperature; D012333:RNA, Messenger / Q000378:metabolism*; D013997:Time Factors; D014452:Ubiquitins / Q000235:genetics*; D014982:Xenopus laevis / Q000235:genetics* / Q000378:metabolism
D012333:RNA, Messenger; D014452:Ubiquitins