Accumulation of iodine-131 and technetium-99m pertechnetate in thyroid carcinoma.
Carcinoma of the thyroid is usually delineated as a cold defect on images with radioiodine and Tc-99m per-technetate. However, several cases that showed an accumulation of Tc-99m pertechnetate in thyroid carcinoma or in their metastases, but did not show any accumulation of radioiodine, have been reported. This paper presents a rare case of an advanced follicular adenocarcinoma of the thyroid that accumulated both Tc-99m pertechnetate and I-131. In this 41-year-old male patient, there were two primary foci in the thyroid; one occupied the whole left lobe with extension to the mediastinum and the other located in the lower part of the right lobe. In addition, there was a lymph node metastasis in the upper mediastinum adjacent to the left lobe. On images with both I-131 and Tc-99m pertechnetate, the tumor in the left lobe and the metastatic lymph node were delineated, but the tumor in the right lobe was not. Accumulation of Tc-99m pertechnetate in the lower part of the tumor of the left lobe was more distinct than that of I-131. Therefore, it is considered that despite similar histologic findings the trapping ability of the cancerous tissue differed from area to area.
Katagiri
M
M
Division of Endocrine Surgery, Kawasaki Medical School, Okayama, Japan.
Suzuki
S
S
Sadahiro
S
S
Kubouchi
K
K
Ohmura
T
T
Tsumura
O
O
Akatsuka
S
S
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000378:metabolism; D000328:Adult; D006801:Humans; D007457:Iodine Radioisotopes / Q000378:metabolism; D008297:Male; D011877:Radionuclide Imaging; D013670:Sodium Pertechnetate Tc 99m / Q000493:pharmacokinetics; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism
D007457:Iodine Radioisotopes; D013670:Sodium Pertechnetate Tc 99m