Nuclear protein(s) binding to the conserved DNA hexameric sequence postulated to regulate transcription of wheat histone genes.
Nuclear protein(s) that specifically bind(s) to the upstream hexamer motif, ACGTCA, of wheat histone H3 and H4 genes has (have) been identified. Sequences homologous to this hexamer are found to be conserved in the upstream region of not only wheat histone genes but also other plant and animal histone genes. This suggests a possible role(s) for the hexamer and the nuclear protein(s) in the transcriptional regulation of the wheat histone genes. This hexamer is homologous to the upstream core sequence, TGACGTCA, which is highly conserved in some animal genes whose expression is regulated by cAMP.
Mikami
K
K
Department of Biology, Faculty of Science, Hokkaido University, Sapporo, Japan.
Tabata
T
T
Kawata
T
T
Nakayama
T
T
Iwabuchi
M
M
D001667:Binding, Competitive; D000242:Cyclic AMP / Q000502:physiology; D004268:DNA-Binding Proteins / Q000502:physiology*; D005786:Gene Expression Regulation; D006657:Histones / Q000235:genetics*; D008745:Methylation; D009687:Nuclear Proteins / Q000502:physiology*; D012045:Regulatory Sequences, Nucleic Acid; D012689:Sequence Homology, Nucleic Acid; D014158:Transcription, Genetic; D014908:Triticum / Q000235:genetics*
D004268:DNA-Binding Proteins; D006657:Histones; D009687:Nuclear Proteins; D000242:Cyclic AMP