[Colorectal tumors and hormonal receptors. A critical review of the literature].
The importance of sexual hormones in the development of cancers of the large bowel is strongly supported experimentally and epidemiologically. The clinical search for the presence of hormonal receptors in the cells of patients operated for tumours of the colon and rectum has been common since 1975. This investigation ought to have opened up new diagnostic and therapeutic prospects for these tumours which have given such a little curative satisfaction. The present review considered reported data. Unfortunately the emerging picture is irregular in cases and results. It is personally considered that these studies are not for the moment likely to produce important novelties for the treatment of tumours of the large bowel tract.
Comandone
A
A
Istituto di Chirurgia d'Urgenza, Università di Torino.
Sciascia
C
C
Enrichens
F
F
Olivero
G
G
Foco
A
A
Fiori
M G
MG
Sanfelici
G
G
Gallingani
R
R
D003110:Colonic Neoplasms / Q000139:chemically induced / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D009376:Neoplasms, Hormone-Dependent / Q000139:chemically induced / Q000378:metabolism* / Q000473:pathology; D011956:Receptors, Cell Surface / Q000378:metabolism*; D011987:Receptors, Steroid / Q000378:metabolism; D012004:Rectal Neoplasms / Q000139:chemically induced / Q000378:metabolism* / Q000473:pathology
D011956:Receptors, Cell Surface; D011987:Receptors, Steroid
Tumori del colon retto e recettori ormonali. Una revisione critica della letteratura.