High-performance liquid chromatographic quantitation of 4-hydroxydebrisoquine in microsomal incubates by use of silica columns, aqueous mobile phase and automated column switching.
Mellström
B
B
Department of Clinical Pharmacology, Karolinska Institute, Huddinge University Hospital, Sweden.
D000328:Adult; D002851:Chromatography, High Pressure Liquid; D003647:Debrisoquin / Q000031:analogs & derivatives / Q000032:analysis* / Q000378:metabolism; D006801:Humans; D007546:Isoquinolines / Q000032:analysis*; D008862:Microsomes, Liver / Q000032:analysis*; D012822:Silicon Dioxide; D013056:Spectrophotometry, Ultraviolet
D007546:Isoquinolines; C012359:4-hydroxydebrisoquin; D012822:Silicon Dioxide; D003647:Debrisoquin