title: Polyneuropathy in hypothyroidism: clinical, electrophysiological and morphological findings in four cases.
abstract: Clinical, neurophysiological and morphological studies of four patients with polyneuropathy and secondary hypothyroidism are reported. Neurophysiological studies revealed signs of muscle denervation and reduction of conduction velocity in all the patients. Sural nerve biopsies showed axonal degeneration in all cases but one. All the patients were treated with replacement therapy and clinical symptomatology and neurophysiological parameters improved in all patients.
authors.affiliation: Department of Neurology, University of Milan, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Nemni
authors.forename: E
authors.initials: E
authors.lastname: Bottacchi
authors.forename: R
authors.initials: R
authors.lastname: Fazio
authors.forename: A
authors.initials: A
authors.lastname: Mamoli
authors.forename: M
authors.initials: M
authors.lastname: Corbo
authors.forename: M
authors.initials: M
authors.lastname: Camerlingo
authors.forename: G
authors.initials: G
authors.lastname: Galardi
authors.forename: L
authors.initials: L
authors.lastname: Erenbourg
authors.forename: N
authors.initials: N
authors.lastname: Canal
mesh_terms: D000200:Action Potentials; D000328:Adult; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000473:pathology; D009431:Neural Conduction; D010523:Peripheral Nervous System Diseases / Q000473:pathology* / Q000503:physiopathology