title: [Adjusting the dosage of netilmicin from two measurements. Program validation].
abstract: The aim of this study is to give to clinicians a well validated usefull tool allowing an increase of safety in the monitoring of netilmicin. During the first administration of the drug, two plasmatic concentrations are measured, and input in a preprogrammed hand-held calculator. A posology and a rythm of administration are returned by the calculator. After six days of this dosage regiment, the peak and the valley concentrations are compared with those previously given by the computer as values at equilibrium. No significant difference can be observed. There is no change in plasmatic creatinine level from the first to the sixth day of treatment. So, a preprogrammed hand-held computer can be convenient and safe to monitor netilmicin.
authors.forename: Y
authors.initials: Y
authors.lastname: Guedes
authors.forename: J F
authors.initials: JF
authors.lastname: Abgrall
authors.forename: M A
authors.initials: MA
authors.lastname: Lebot
authors.forename: T
authors.initials: T
authors.lastname: Voirin
authors.forename: D
authors.initials: D
authors.lastname: L'Azou
authors.forename: M
authors.initials: M
authors.lastname: Dheilly
authors.forename: R L
authors.initials: RL
authors.lastname: Tanguy
authors.forename: J
authors.initials: J
authors.lastname: Le Garrec
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003404:Creatinine / Q000097:blood; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008838:Microcomputers; D008875:Middle Aged; D009428:Netilmicin / Q000008:administration & dosage* / Q000097:blood / Q000493:pharmacokinetics
chemical_list: D009428:Netilmicin; D003404:Creatinine
vernacular_title: Adaptation des posologies de la nétilmicine à partir de deux points. Validation d'un programme.