Haplotypes of alpha-globin-gene in the Saudi population--the triplicated gene (alpha alpha alpha anti 3.7/).
Using restriction endonucleases Bam HI, Bg1 II, Hpa I, Hind III and Xba I, the alpha alpha alpha anti 3.7/ haplotype was studied in the Saudi population. This paper presents the frequency of the alpha gene haplotype alpha alpha alpha anti 3.7/ in different regions of Saudi Arabia, where thalassaemia occurs at a high frequency.
el-Hazmi
M A
MA
Department of Medical Biochemistry, College of Medicine, King Khalid Hospital, Riyadh, Saudi Arabia.
D004247:DNA / Q000235:genetics; D004262:DNA Restriction Enzymes; D005787:Gene Frequency; D005914:Globins / Q000235:genetics*; D006239:Haplotypes; D006801:Humans; D005810:Multigene Family; D012529:Saudi Arabia; D013789:Thalassemia / Q000097:blood / Q000235:genetics
D005914:Globins; D004247:DNA; D004262:DNA Restriction Enzymes