Detection of human rotaviruses which do not react with subgroup I- and II-specific monoclonal antibodies.
Of 126 rotavirus-positive specimens, 7 could not be subgrouped (I or II). These strains showed a distinct reaction with a monoclonal antibody recognizing a common region on VP6, but they did not react with VP6 subgroup-specific monoclonal antibodies although they contained as much viral antigen as the subgrouped strains.
Svensson
L
L
Department of Virology, Karolinska Institute, School of Medicine, Stockholm, Sweden.
Grahnquist
L
L
Pettersson
C A
CA
Grandien
M
M
Stintzing
G
G
Greenberg
H B
HB
D000911:Antibodies, Monoclonal / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D012367:RNA, Viral / Q000032:analysis; D012401:Rotavirus / Q000145:classification / Q000276:immunology* / Q000302:isolation & purification; D014764:Viral Proteins / Q000276:immunology*; D015678:Viral Structural Proteins
D000911:Antibodies, Monoclonal; D012367:RNA, Viral; D014764:Viral Proteins; D015678:Viral Structural Proteins