title: Expression of C-type viral particles at implantation in the marmoset monkey.
abstract: Type C RNA retroviral particles have been observed budding from the plasma membrane of syncytiotrophoblast during a study of embryo implantation in the common marmoset (Callithrix jacchus). These viral particles appear in profusion at the interface of syncytiotrophoblast with cytotrophoblast. They appear to be a non-infective, endogenous viral component of the host genome, although the precise role of the C-type virus in this context is unclear at present. Such viral particles have been reported previously from studies of human term placenta; however, this is the first report indicating that expression of viral particles occurs at the earliest stages of embryo implantation.
authors.affiliation: MRC/AFRC Comparative Physiology Research Group, Zoological Society of London, UK.
authors.forename: C A
authors.initials: CA
authors.lastname: Smith
authors.forename: H D
authors.initials: HD
authors.lastname: Moore
mesh_terms: D000818:Animals; D002144:Callithrix; D002462:Cell Membrane / Q000382:microbiology* / Q000648:ultrastructure; D004624:Embryo Transfer; D005260:Female; D066298:In Vitro Techniques; D008854:Microscopy, Electron; D011247:Pregnancy; D012190:Retroviridae / Q000648:ultrastructure; D013997:Time Factors; D014327:Trophoblasts / Q000382:microbiology* / Q000648:ultrastructure; D014412:Tumor Virus Infections / Q000382:microbiology*