Immunocytochemical and ultrastructural findings in a mature retroperitoneal teratoma.
Report is made of a mature retroperitoneal teratoma in a 32-year-old man. Investigation of the tumor revealed cells immunoreactive for ACTH, Met-enkephalin, beta-LPH, serotonin, FSH, BPP, S100, Neuron-specific-enolase. These cells were mainly present in the glandular epithelium, lining the cysts of the tumor. Ultrastructurally, neuro-secretory granules were demonstrated in the cytoplasm of the tumoral endocrine cells. At no time did the patient display endocrine symptoms.
Warson
F
F
Department of Pathology, Academic Hospital, Vrije Universiteit Brussel, Belgium.
Smets
G
G
Gepts
W
W
Velkeniers
B
B
Vanhaelst
L
L
Sacre
R
R
Peters
O
O
D000324:Adrenocorticotropic Hormone / Q000032:analysis; D000328:Adult; D004744:Enkephalin, Methionine / Q000032:analysis; D005640:Follicle Stimulating Hormone / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D010191:Pancreatic Polypeptide / Q000032:analysis; D010751:Phosphopyruvate Hydratase / Q000032:analysis; D012186:Retroperitoneal Neoplasms / Q000032:analysis* / Q000648:ultrastructure; D009418:S100 Proteins / Q000032:analysis; D012701:Serotonin / Q000032:analysis; D013724:Teratoma / Q000032:analysis* / Q000648:ultrastructure; D008083:beta-Lipotropin / Q000032:analysis
D009418:S100 Proteins; D012701:Serotonin; D004744:Enkephalin, Methionine; D010191:Pancreatic Polypeptide; D000324:Adrenocorticotropic Hormone; D005640:Follicle Stimulating Hormone; D008083:beta-Lipotropin; D010751:Phosphopyruvate Hydratase