[Malignant schwannoma with the microscopic features of a malignant fibrous histiocytoma].
A case of malignant schwannoma is described in which the primary tumor showed morphologic signs of malignant fibrous histiocytoma, but these were not confirmed by immunohistochemical assays which were negative for markers of histiocytic tumors such as alpha 1-antitrypsin and alpha 1-antichymotrypsin. In the recurring tumor, typical palisade structures were found. Difficulties attending the diagnostic differentiation of these two tumors are discussed. It is concluded that histogenetic characteristics of malignant fibrous histiocytomas must be known to be able to establish more precise criteria on which the differentiation may be based.
Nikitin
A Iu
AIu
D014408:Biomarkers, Tumor / Q000032:analysis; D003937:Diagnosis, Differential; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000473:pathology*; D009442:Neurilemmoma / Q000175:diagnosis / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000473:pathology*; D013848:Thigh
D014408:Biomarkers, Tumor
Zlokachestvennaia shvannoma s mikroskopicheskimi chertami zlokachestvennoĭ fibroznoĭ gistiotsitomy.