Disseminated warts and evolving squamous cell carcinoma in a patient with acquired immunodeficiency syndrome.
A patient with acquired immunodeficiency syndrome developed widespread verrucous lesions on the hands, feet, and penis. Histologic analysis revealed typical changes of verruca vulgaris and, from several sites, a transformation toward squamous cell carcinoma. Southern blot analysis of deoxyribonucleic acid from penile wart tissue indicated the presence of a type of human papillomavirus that rarely is associated with carcinoma.
Milburn
P B
PB
Department of Dermatology, State University of New York Health Science Center, Brooklyn 1203-2098.
Brandsma
J L
JL
Goldsman
C I
CI
Teplitz
E D
ED
Heilman
E I
EI
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000382:microbiology; D004279:DNA, Viral / Q000032:analysis; D006801:Humans; D007118:Immunoassay; D008297:Male; D027383:Papillomaviridae / Q000276:immunology; D010409:Penile Diseases / Q000150:complications; D012871:Skin Diseases / Q000150:complications* / Q000473:pathology; D012878:Skin Neoplasms / Q000150:complications* / Q000382:microbiology; D014860:Warts / Q000150:complications* / Q000473:pathology
D004279:DNA, Viral