title: Mitochondrial DNA polymorphism among five Asian populations.
abstract: Mitochondrial DNA (mtDNA) polymorphisms were detected using 13 restriction enzymes on the total DNA obtained from blood samples of five Asian populations: Japanese and Ainu of northern Japan, Korean, Negrito (Aeta) of the Philippines, and Vedda of Sri Lanka. Of a total of 28 restriction-enzyme morphs detected, eight had not been reported previously. By combining the morphs, we were able to classify mtDNAs of 243 individuals into 20 mtDNA types. Phylogenetic analyses using maximum parsimony and genetic distance methods both showed that the Japanese, Ainu, and Korean populations were closely related to each other. Aeta was found to show a relatively close relationship to these three populations, confirming the conclusion from previous studies of blood markers. In contrast, Vedda was quite different from the other four populations.
authors.affiliation: Department of Anthropology, Faculty of Science, University of Tokyo, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Harihara
authors.forename: N
authors.initials: N
authors.lastname: Saitou
authors.forename: M
authors.initials: M
authors.lastname: Hirai
authors.forename: T
authors.initials: T
authors.lastname: Gojobori
authors.forename: K S
authors.initials: KS
authors.lastname: Park
authors.forename: S
authors.initials: S
authors.lastname: Misawa
authors.forename: S B
authors.initials: SB
authors.lastname: Ellepola
authors.forename: T
authors.initials: T
authors.lastname: Ishida
authors.forename: K
authors.initials: K
authors.lastname: Omoto
mesh_terms: D001208:Asia; D004262:DNA Restriction Enzymes; D004272:DNA, Mitochondrial / Q000235:genetics*; D005006:Ethnicity; D006801:Humans; D007194:India; D007564:Japan; D007723:Korea; D010802:Phylogeny; D011110:Polymorphism, Genetic
chemical_list: D004272:DNA, Mitochondrial; D004262:DNA Restriction Enzymes