Synthesis of 18F-labelled 2-fluoro-1,4-quinones using acetylhypofluorite.
The fluorination of 1,4-benzo- and naphthoquinones using [18F]acetylhypofluorite is described. For compounds with electron-donating substituents fair to good radiochemical yields have been reached.
Herscheid
J D
JD
Radio-Nuclide-Centre (RNC), Free University, Amsterdam, The Netherlands.
Wedzinga
R
R
Verboom
W
W
Visser
G W
GW
D000085:Acetates; D004952:Esters; D005461:Fluorine; D005462:Fluorine Radioisotopes; D011809:Quinones / Q000138:chemical synthesis*
D000085:Acetates; D004952:Esters; D005462:Fluorine Radioisotopes; D011809:Quinones; D005461:Fluorine; C040801:acetyl hypofluorite