Wilms tumor and the VATER association.
We describe an infant with the VATER association in whom a Wilms tumor was noted when she was 5 months old. The lower pole tumor arose near the pelvis and grew into an adjacent calix producing a cystic and solid mass with numerous papillary projections resembling sarcoma botryoides. Histopathologically, the tumor was a classical Wilms tumor but it was unusual in that the papillary projections of the tumor were covered by intestinal-like epithelium, which was interpreted as metaplastic urothelium. The margins were free of tumor and the patient is being treated according to the National Wilms Tumor Study Protocol for stage I lesions. She is currently without evidence of recurrence.
Reinberg
Y
Y
Department of Pediatric Surgery, Minneapolis Children's Medical Center, Minnesota.
Anderson
G F
GF
Franciosi
R
R
Manivel
C
C
Dehner
L P
LP
Burke
B A
BA
D000015:Abnormalities, Multiple / Q000473:pathology*; D001006:Anus, Imperforate / Q000473:pathology; D004947:Esophagus / Q000002:abnormalities; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D013131:Spine / Q000002:abnormalities; D009396:Wilms Tumor / Q000473:pathology*