Demonstration of papillomavirus structural antigen in human urinary bladder neoplasia.
Clear cells showing characteristic features of koilocytotic atypia were found in 41 (82%) of 50 paraffin sections of urinary bladder tumour. Papillomavirus common structural antigen was detected in seven (14%) of the samples using an avidin-biotin peroxidase staining technique. The results suggest a role for the human papillomavirus in the aetiology of urinary bladder neoplasia.
Bryant
P
P
Department of Pathology, Princess of Wales Hospital, Bridgend.
Skelly
J
J
Wilson
D
D
D000368:Aged; D000369:Aged, 80 and over; D000957:Antigens, Viral, Tumor / Q000032:analysis*; D002295:Carcinoma, Transitional Cell / Q000276:immunology / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D027383:Papillomaviridae / Q000276:immunology*; D001749:Urinary Bladder Neoplasms / Q000276:immunology* / Q000473:pathology
D000957:Antigens, Viral, Tumor