Recombinant human interleukin 5 is a selective activator of human eosinophil function.
Human rIL-5 was found to selectively stimulate morphological changes and the function of human eosinophils. This molecule is thus a prime candidate for the selective eosinophilia and eosinophil activation seen in disease.
Lopez
A F
AF
Division of Human Immunology, Institute of Medical and Veterinary Science, Adelaide, South Australia.
Sanderson
C J
CJ
Gamble
J R
JR
Campbell
H D
HD
Young
I G
IG
Vadas
M A
MA
D004804:Eosinophils / Q000187:drug effects* / Q000502:physiology / Q000648:ultrastructure; D006801:Humans; D015848:Interleukin-5; D007378:Interleukins / Q000494:pharmacology*; D009504:Neutrophils / Q000187:drug effects; D011994:Recombinant Proteins / Q000494:pharmacology; D013481:Superoxides / Q000096:biosynthesis
D015848:Interleukin-5; D007378:Interleukins; D011994:Recombinant Proteins; D013481:Superoxides