Linear IgA deposition associated with cutaneous varicella-zoster infection: a case report.
The homogeneous linear deposition of IgA along the basement membrane zone of uninvolved skin is a distinguishing feature of linear IgA dermatosis in adults and chronic bullous dermatosis of childhood. Although linear IgA deposition may be seen in other cutaneous diseases, to our knowledge, there are no previous reports of a direct association with cutaneous infection. We describe the finding of intense fluorescence, in a linear pattern, of IgA at the basement membrane zone in an elderly man with disseminated cutaneous varicella-zoster infection.
Blickenstaff
R D
RD
Department of Dermatology, Mayo Clinic, Rochester, MN 55905.
Perry
H O
HO
Peters
M S
MS
D000212:Acyclovir / Q000627:therapeutic use; D000368:Aged; D001485:Basement Membrane / Q000276:immunology; D001768:Blister / Q000382:microbiology; D005455:Fluorescent Antibody Technique; D006562:Herpes Zoster / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology; D014645:Herpesvirus 3, Human / Q000254:growth & development; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology*; D008297:Male; D012867:Skin
D007070:Immunoglobulin A; D000212:Acyclovir