Peripheral neurotoxicity in workers exposed to inorganic mercury compounds.
Nerve conduction velocity (NCV) of the median motor, median sensory, and sural nerves was assessed in 16 workers chronically exposed to various inorganic mercury compounds. Exposed workers were compared with an unexposed control group using t test analyses. Slowing of the median motor nerve NCV was found, which was correlated with both increased levels of mercury in blood and urine, and with increased number of neurologic symptoms. Sensitive evaluation of neural function was found to be practical and informative for investigating mercury toxicity. Such evaluation can help determine safe mercury levels at the workplace.
Singer
R
R
Environmental Sciences Laboratory, Mount Sinai School of Medicine, New York, New York.
Valciukas
J A
JA
Rosenman
K D
KD
D000328:Adult; D000368:Aged; D002617:Chemical Industry; D006801:Humans; D008475:Median Nerve / Q000503:physiopathology; D008628:Mercury / Q000652:urine; D008630:Mercury Poisoning / Q000503:physiopathology* / Q000652:urine; D008875:Middle Aged; D009431:Neural Conduction; D009475:Neurons, Afferent / Q000503:physiopathology; D009784:Occupational Diseases / Q000139:chemically induced* / Q000503:physiopathology / Q000652:urine; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000503:physiopathology / Q000652:urine; D013497:Sural Nerve / Q000503:physiopathology
D008628:Mercury