title: [Spontaneous regression of a large liver tumor with markedly elevated serum enzyme levels].
abstract: The case of a liver tumor of 10 cm diameter in a 32-year-old asymptomatic woman is described with markedly elevated liver enzymes in the serum (transaminases and alkaline phosphatase). The tumor corresponded to a focal nodular hyperplasia or a hepatic adenoma. The regression of this hepatic tumor over a time period of 18 months after discontinuation of oral contraceptives was observed as well as a complete normalisation of laboratory findings. It is concluded that conservative management after withdrawal of hormonal contraception my be the preferable treatment for hepatic adenoma and focal nodular hyperplasia.
authors.affiliation: Abt. für Gastroenterologie und Endokrinologie, Zentrum Innere Medizin, Universität Göttingen.
authors.forename: E G
authors.initials: EG
authors.lastname: Siegel
authors.forename: H
authors.initials: H
authors.lastname: Hartmann
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000139:chemically induced / Q000473:pathology*; D003937:Diagnosis, Differential; D004798:Enzymes / Q000097:blood; D004997:Ethinyl Estradiol / Q000009:adverse effects; D019304:Ethinyl Estradiol-Norgestrel Combination; D005260:Female; D006801:Humans; D006965:Hyperplasia; D008099:Liver / Q000473:pathology; D008111:Liver Function Tests; D008113:Liver Neoplasms / Q000139:chemically induced / Q000473:pathology*; D009365:Neoplasm Regression, Spontaneous; D009644:Norgestrel / Q000009:adverse effects; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D004798:Enzymes; D009644:Norgestrel; D004997:Ethinyl Estradiol; D019304:Ethinyl Estradiol-Norgestrel Combination
vernacular_title: Spontane Rückbildung eines grossen Lebertumors mit deutlich erhöhten Serumenzymspiegeln.