title: Immunoperoxidase localization of HSV2 antigens in cervical dysplasia and carcinoma.
abstract: The AA. have evaluated by means of the immunohistochemical technique the incidence of herpetic phlogosis in 76 women with neoplastic pathologies of the uterine cervix. The patients were submitted to cytologic, colposcopic and histologic examination for CIN. The HSV2 positivity by immunohistochemical method was demonstrated in 53 (35.3%) cases of CIN and invasive carcinoma. The results confirm the frequent association between HSV2 and cervical carcinoma and they support a specific therapeutic approach to be made in the prevention and clinical management of the carcinoma.
authors.affiliation: Institute of Obstetric and Gynecology, University of Cagliari, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Setzu
authors.forename: P
authors.initials: P
authors.lastname: Puligheddu
authors.forename: C
authors.initials: C
authors.lastname: Marcello
authors.forename: G
authors.initials: G
authors.lastname: Parodo
authors.forename: C
authors.initials: C
authors.lastname: Liguori
authors.forename: A
authors.initials: A
authors.lastname: Zucca
authors.forename: U
authors.initials: U
authors.lastname: Lecca
mesh_terms: D000328:Adult; D000956:Antigens, Viral / Q000032:analysis*; D005260:Female; D006558:Herpes Genitalis / Q000175:diagnosis*; D006801:Humans; D007124:Immunoenzyme Techniques; D008875:Middle Aged; D018139:Simplexvirus / Q000276:immunology*; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis*; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis*
chemical_list: D000956:Antigens, Viral