[Biological criteria for the evaluation of prophylactic treatment with a low molecular weight heparin (Kabi 2165)].
Efficacy of a low molecular weight heparin (Kabi 2165) was compared with that of non-fractionated heparin in the prevention of abdominal surgery postoperative venous thrombosis by means of a double-blind randomized trial in 79 patients. Determination of D. dimers in these patients allowed assessment of specificity of this assay for detection of postoperative venous thrombosis.
Le Querrec
A
A
Département d'Anesthésiologie, C.H.U. Côte de Nacre, Caen.
Derlon
A
A
Deshayes
J P
JP
Lefrançois
C
C
Sillard
B
B
Delassus
P
P
Viel
J F
JF
Kher
A
A
Thomas
M
M
D000005:Abdomen / Q000601:surgery; D001780:Blood Coagulation Tests; D004311:Double-Blind Method; D004341:Drug Evaluation; D005170:Factor X / Q000032:analysis; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D006493:Heparin / Q000627:therapeutic use*; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use*; D006801:Humans; D011183:Postoperative Complications / Q000517:prevention & control*; D011897:Random Allocation; D013923:Thromboembolism / Q000517:prevention & control*
D005338:Fibrin Fibrinogen Degradation Products; D006495:Heparin, Low-Molecular-Weight; D005170:Factor X; D006493:Heparin
Critères biologiques d'évaluation d'un traitement prophylactique par une héparine de bas poiids moléculaire (Kabi 2,165).