Subclinical measles infection in vaccinated seropositive individuals in arctic Greenland.
Measles vaccination was performed in the arctic district of Scoresbysund, Greenland in 1968, which had never been exposed to natural measles. More than 90% of the total population was vaccinated and a 94-100% seroconversion was obtained. During a serological survey to examine the immunity status of the vaccinees, it was discovered that a temporary increase in measles antibodies took place in the majority of the population 2-4 years after the vaccination. This was not accompanied by clinically observed measles. Most likely, it was due to an inapparent measles infection in a population considered highly immune after vaccination.
Pedersen
I R
IR
Institute of Medical Microbiology, University of Copenhagen, Denmark.
Mordhorst
C H
CH
Glikmann
G
G
von Magnus
H
H
D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D001110:Arctic Regions; D004797:Enzyme-Linked Immunosorbent Assay; D006116:Greenland; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D008457:Measles / Q000276:immunology*; D008458:Measles Vaccine / Q000276:immunology*; D012698:Serologic Tests; D013997:Time Factors; D014611:Vaccination
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D008458:Measles Vaccine