[Thrombolytic treatment of acute arterial thrombosis].
We have treated 14 patients with acute arterial thrombosis with intravenous infusion of streptokinase using a standard dosage scheme. The indication for treatment was critical ischemia due to arterial thrombosis and a presence of symptoms for less than 30 days. The arteriography showed no possibility of reconstructive vascular surgery. The results showed that this treatment is not a good alternative for this group of patients. On the same indications we also treated two patients with intra-arterial infusion of streptokinase at a dosage of 5,000 U per hour. Successful thrombolysis was achieved in both patients. Arteriograms demonstrated that the small distal vessels were opened, along with the femoro-popliteal segment, which showed significant stenosis. The patients could then be helped by reconstructive vascular surgery. We conclude that thrombolysis with intra-arterial infusion of streptokinase is a good choice as the initial treatment for this group of patients. However, the follow-up must include immediate reconstructive vascular surgery or radiological treatment with PTA.
Mjåset
B
B
Høivik
B
B
Holager
G
G
D000208:Acute Disease; D000368:Aged; D005500:Follow-Up Studies; D006801:Humans; D007261:Infusions, Intra-Arterial; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D011150:Popliteal Artery / Q000000981:diagnostic imaging; D011859:Radiography; D013300:Streptokinase / Q000008:administration & dosage*; D013927:Thrombosis / Q000188:drug therapy*
D013300:Streptokinase
Trombolytisk behandling ved akutte arterielle tromboser.