title: Recent respiratory and enteric adenovirus infection in children in the Manchester area.
abstract: Seventy-three group B adenoviruses (29 type 3 and 44 type 7) identified in a recent community outbreak were analysed with restriction endonucleases. Considerable genetic heterogeneity was identified, particularly amongst the type 3 isolates, but this genome variation could not be correlated with either clinical or epidemiological findings. Group F adenoviruses were found in 132 (4.1%) of 3202 stool specimens from children with gastroenteritis and, after rotaviruses, they were the most common viruses identified. Unlike rotaviruses, these enteric adenoviruses were endemic throughout the 3-year study period and the greatest proportion of infections (47.6%) were found in babies under 6 months old.
authors.affiliation: North Manchester Regional Virus Laboratory, Booth Hall Children's Hospital.
authors.forename: S J
authors.initials: SJ
authors.lastname: Richmond
authors.forename: D J
authors.initials: DJ
authors.lastname: Wood
authors.forename: A S
authors.initials: AS
authors.lastname: Bailey
mesh_terms: D000257:Adenoviridae Infections / Q000453:epidemiology*; D000258:Adenovirus Infections, Human / Q000453:epidemiology*; D000367:Age Factors; D002675:Child, Preschool; D004196:Disease Outbreaks; D004739:England; D005759:Gastroenteritis / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D007223:Infant; D012141:Respiratory Tract Infections / Q000453:epidemiology* / Q000382:microbiology; D012400:Rotavirus Infections / Q000453:epidemiology