[Serotonin receptors in the brain of animals selected for their domesticated type of behavior].
Participation was studied of central serotonin receptors of the first and second types in behaviour change of animals selected by the character of defensive reaction to man. Serotonin receptors were determined by radioligand method by binding of the brain preparations 3H-serotonin and 3H-spiperone. An increase of C2 receptors number was found in the frontal brain cortex of the tame brown rats in comparison with the aggressive ones. Differences were not found in specific C1-receptor binding in the frontal brain cortex of tame and aggressive brown rats, silver foxes and American minks in various relatively early selection stages. It is supposed that disappearance of aggressive reaction to man at domestication is connected with an increase of C2 receptors number.
Maslova
G B
GB
Avgustinovich
D F
DF
D000374:Aggression / Q000502:physiology; D000818:Animals; D000829:Animals, Domestic; D000835:Animals, Wild; D001522:Behavior, Animal / Q000502:physiology*; D001921:Brain / Q000502:physiology*; D001923:Brain Chemistry / Q000502:physiology; D005589:Foxes; D008907:Mink; D011869:Radioligand Assay; D051381:Rats; D011985:Receptors, Serotonin / Q000032:analysis / Q000502:physiology*; D012641:Selection, Genetic
D011985:Receptors, Serotonin
Serotoninovye retseptory v mozge zhivotnykh, selektsioniruemykh na domestikatsionnyĭ tip povedeniia.