Inhibition of the release of prostaglandins, thromboxanes, and leukotrienes from anaphylactic lungs by a platelet-activating factor (PAF) antagonist and its stimulation by PAF.
Sirois
P
P
Department of Pediatrics and Pharmacology, Faculty of Medicine, University of Sherbrooke, P.Q., Canada.
Harczy
M
M
Braquet
P
P
Borgeat
P
P
Maclouf
J
J
Pradelles
P
P
D015121:6-Ketoprostaglandin F1 alpha / Q000378:metabolism; D000707:Anaphylaxis / Q000503:physiopathology*; D000818:Animals; D015232:Dinoprostone; D005231:Fatty Acids, Unsaturated / Q000378:metabolism*; D006168:Guinea Pigs; D066298:In Vitro Techniques; D007975:Leukotriene B4 / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D010972:Platelet Activating Factor / Q000037:antagonists & inhibitors / Q000502:physiology*; D011458:Prostaglandins E / Q000378:metabolism; D013189:SRS-A / Q000378:metabolism; D013929:Thromboxane B2 / Q000378:metabolism
D005231:Fatty Acids, Unsaturated; D010972:Platelet Activating Factor; D011458:Prostaglandins E; D013189:SRS-A; D007975:Leukotriene B4; D013929:Thromboxane B2; D015121:6-Ketoprostaglandin F1 alpha; D015232:Dinoprostone