Cancer family syndrome of Lynch.
This report describes a family in whom eight cancers (six colonic and two endometrial) occurred in seven relatives. The colonic cancer was diagnosed in five of the six affected patients at an unusually young age, had a predilection for the proximal colon, and was of the mucinous type in four patients. Polyposis was not found in any colon. The occurrence of cancer in this kindred is characteristic of the "cancer family syndrome" of Lynch.
Abusamra
H
H
Department of Medicine E, Edith Wolfson Medical Center, Holon, Israel.
Maximova
S
S
Bar-Meir
S
S
Krispin
M
M
Rotmensch
H H
HH
D002288:Adenocarcinoma, Mucinous / Q000235:genetics*; D000328:Adult; D003110:Colonic Neoplasms / Q000235:genetics*; D005260:Female; D006801:Humans; D007557:Israel; D008297:Male; D009386:Neoplastic Syndromes, Hereditary / Q000235:genetics*; D010375:Pedigree; D014594:Uterine Neoplasms / Q000235:genetics*