Glucagonoma syndrome.
A 53-year-old Japanese man with a skin eruption characteristic of glucagonoma syndrome had had misdiagnoses for 10 years. The plasma glucagon level was not abnormally high on the first admission, and 4 years later the level was elevated as determined by the 30 gm arginine tolerance test. An alpha cell carcinoma detected in the tail of the pancreas was associated with a lymph node metastasis; the skin eruption cleared up 10 days after the partial pancreatectomy with lymphadenectomy. The clinical features of glucagonoma syndrome should be given attention.
Hashizume
T
T
Department of Dermatology, Saga Prefectural Hospital, Japan.
Kiryu
H
H
Noda
K
K
Kano
T
T
Nakano
R
R
D007516:Adenoma, Islet Cell / Q000097:blood*; D001120:Arginine; D003951:Diagnostic Errors; D005934:Glucagon / Q000097:blood; D005935:Glucagonoma / Q000097:blood* / Q000150:complications / Q000473:pathology; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000097:blood* / Q000150:complications / Q000473:pathology; D012871:Skin Diseases / Q000175:diagnosis* / Q000209:etiology; D013577:Syndrome
D005934:Glucagon; D001120:Arginine