title: Cytogenetic abnormalities in a primitive neuroectodermal tumor.
abstract: Two distinct karyotypically abnormal cell lines were observed in cultures of a primitive neuroectodermal tumor. One involved multiple chromosome rearrangements, and the other an inversion of chromosome #7 and a t(3;10) showing an interstitial deletion of 3p; del(3)(p1?4p1?2). None of these rearrangements have been reported in previous descriptions of primitive neuroectodermal tumor karyotypes.
authors.affiliation: Department of Human Genetics, University of Newcastle upon Tyne, England.
authors.forename: N P
authors.initials: NP
authors.lastname: Bown
authors.forename: E V
authors.initials: EV
authors.lastname: Davison
authors.forename: A D
authors.initials: AD
authors.lastname: Pearson
authors.forename: A J
authors.initials: AJ
authors.lastname: Malcolm
mesh_terms: D002648:Child; D002869:Chromosome Aberrations; D002879:Chromosomes, Human, Pair 10; D002893:Chromosomes, Human, Pair 3; D002897:Chromosomes, Human, Pair 7; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D008297:Male; D008441:Maxillary Neoplasms / Q000235:genetics*; D009373:Neoplasms, Germ Cell and Embryonal / Q000235:genetics*; D014178:Translocation, Genetic
chemical_list: D005819:Genetic Markers