title: DNAs of the two mating-type alleles of Neurospora crassa are highly dissimilar.
abstract: The mating-type alleles A and a of Neurospora crassa control mating in the sexual cycle and function in establishing heterokaryon incompatibility in the vegetative cycle. The A and a alleles were cloned, and they were shown to encode both the sexual functions and vegetative incompatibility. The mating-type clones contain nonhomologous DNA segments that are flanked by common DNA sequences. Neurospora crassa and all heterothallic and pseudohomothallic Neurospora species contain a single copy of one mating-type sequence or the other within each haploid genome. The six known self-fertile homothallic isolates contain an A homolog, but only one species also contains a homologous sequences. Homothallism in these species is not due to mating-type switching, as it is in Saccharomyces cerevisiae.
authors.affiliation: Department of Physiological Chemistry, University of Wisconsin, Madison 53706.
authors.forename: N L
authors.initials: NL
authors.lastname: Glass
authors.forename: S J
authors.initials: SJ
authors.lastname: Vollmer
authors.forename: C
authors.initials: C
authors.lastname: Staben
authors.forename: J
authors.initials: J
authors.lastname: Grotelueschen
authors.forename: R L
authors.initials: RL
authors.lastname: Metzenberg
authors.forename: C
authors.initials: C
authors.lastname: Yanofsky
mesh_terms: D002874:Chromosome Mapping; D004262:DNA Restriction Enzymes / Q000235:genetics; D004271:DNA, Fungal; D005800:Genes, Fungal; D049770:Genes, Mating Type, Fungal; D000072235:Mating Factor; D009491:Neurospora / Q000235:genetics*; D009492:Neurospora crassa / Q000235:genetics*; D010455:Peptides / Q000235:genetics*
chemical_list: D004271:DNA, Fungal; D010455:Peptides; D000072235:Mating Factor; D004262:DNA Restriction Enzymes