Plasma levels of atrial natriuretic peptide in hyperthyroidism.
We measured plasma atrial natriuretic peptide (ANP) levels in 17 patients with newly diagnosed thyrotoxicosis. ANP was elevated compared to a group of healthy controls and fell to normal after treatment. Plasma cyclic guanosine monophosphate was also raised in untreated patients. Elevated circulating levels of ANP may play a part in the haemodynamic changes of hyperthyroidism.
Woolf
A S
AS
Endocrine Unit, Whittington Hospital, London, UK.
Moult
P J
PJ
D000328:Adult; D009320:Atrial Natriuretic Factor / Q000097:blood*; D002231:Carbimazole / Q000627:therapeutic use; D006152:Cyclic GMP / Q000097:blood; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood* / Q000188:drug therapy; D008875:Middle Aged; D011441:Propylthiouracil / Q000627:therapeutic use; D013971:Thyrotoxicosis / Q000097:blood / Q000188:drug therapy
D011441:Propylthiouracil; D009320:Atrial Natriuretic Factor; D002231:Carbimazole; D006152:Cyclic GMP