title: Kinetic studies on the ATP- and ubiquitin-dependent proteolytic system of reticulocytes.
abstract: Half-maximal rate of the ATP- and ubiquitin-dependent proteolysis of rabbit reticulocytes, determined in a cell-free system, require 0.5 mg/ml of mitochondria-containing stroma (MCS) protein at a fixed ATP concentration or 100 microM ATP at a fixed protein concentration. 20 microM hemin caused 50% inhibition of degradation of MCS.
authors.affiliation: Institute of Biochemistry, Humboldt University Berlin, GDR.
authors.forename: W
authors.initials: W
authors.lastname: Dubiel
authors.forename: I
authors.initials: I
authors.lastname: Drung
authors.forename: M
authors.initials: M
authors.lastname: Müller
authors.forename: S M
authors.initials: SM
authors.lastname: Rapoport
mesh_terms: D000255:Adenosine Triphosphate / Q000494:pharmacology*; D000818:Animals; D006427:Hemin / Q000494:pharmacology; D007700:Kinetics; D010447:Peptide Hydrolases / Q000097:blood*; D010710:Phosphates / Q000097:blood; D011817:Rabbits; D012156:Reticulocytes / Q000201:enzymology*; D014452:Ubiquitins / Q000494:pharmacology*
chemical_list: D010710:Phosphates; D014452:Ubiquitins; D006427:Hemin; D000255:Adenosine Triphosphate; D010447:Peptide Hydrolases