title: [The effect of biomaterials on cytochrome c].
abstract: The adsorption of ferricytochrome c and ferrocytochrome c on biomaterials was studied by measuring the spectrum of samples assuming the molar extinction coefficients of the ferricytochrome c and ferrocytochrome c at 480 nm and 550 nm. Silica, alumina ceramic, zirconium ceramic, tricalcium phosphate ceramic, hydroxyapatite ceramic, unidirectional calcium phosphate glass-ceramic, bulk crystallized calcium phosphate glass-ceramic and bulk crystallized calcium phosphate glass-ceramic containing large amount of titanium were used as adsorbents. The adsorption of ferricytochrome c or ferrocytochrome c on silica essentially followed the Langumuir adsorption isotherm. Quantitative analysis showed that ferricytochrome c was adsorbed more and dissolved less than ferrocytochrome c on batch adsorption on silica. Total amounts of adsorbed and non-adsorbed ferricytochrome c increased significantly in batch adsorption of ferrocytochrome c on silica. From these experiments it appears that materials such as silica induce a transfer of electrons of cytochrome c.
authors.affiliation: Department of Orthopaedic Surgery, Gunma University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Nagase
authors.forename: M
authors.initials: M
authors.lastname: Chigira
authors.forename: T
authors.initials: T
authors.lastname: Shimizu
authors.forename: T
authors.initials: T
authors.lastname: Shinozaki
authors.forename: E
authors.initials: E
authors.lastname: Udagawa
mesh_terms: D000327:Adsorption; D001672:Biocompatible Materials / Q000494:pharmacology*; D002516:Ceramics / Q000494:pharmacology; D003574:Cytochrome c Group / Q000032:analysis / Q000378:metabolism*; D012822:Silicon Dioxide / Q000494:pharmacology
chemical_list: D001672:Biocompatible Materials; D003574:Cytochrome c Group; D012822:Silicon Dioxide