[The significance of liver changes as the cause of death in kidney transplant patients (an analysis of 68 autopsy cases)].
An analysis of 68 autopsy cases from a total of 950 patients with renal transplantation in Berlin in 1970-1986 shows an average age at death of 39,6 years (15-56 years). The period between renal transplantation and death averaged 51,2 months (range: 1-912 months). Liver failure was the immediate cause of death in 30 cases. In 28 cases the liver disease was a secondary disease. The risk of dying from a liver disease rose with the interval between renal transplantation and death. 61-192 months after renal transplantation, liver disease was the cause of death in 70% of the deceased. Liver cirrhosis was observed in 24 patients (age 21-56 years) after a period from 24-192 months. In 1 case a liver carcinoma developed in a cirrhotic liver. 11 patients died in coma hepaticum, 29 patients had a chronic hepatitis. The findings are compared with clinical studies and individual autopsy reports and contrasted to causes of death in patients with chronic dialysis.
Reinke
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Klinik für Innere Medizin Theodor Brugsch, Humboldt-Universität zu Berlin, DDR.
David
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Scholz
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D000293:Adolescent; D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000150:complications; D002423:Cause of Death; D002908:Chronic Disease; D005260:Female; D006501:Hepatic Encephalopathy / Q000150:complications; D006505:Hepatitis / Q000150:complications; D006801:Humans; D016030:Kidney Transplantation; D008103:Liver Cirrhosis / Q000150:complications; D008107:Liver Diseases / Q000150:complications / Q000401:mortality* / Q000473:pathology; D008113:Liver Neoplasms / Q000150:complications; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
Die Bedeutung von Leberveränderungen als Todesursache bei Nierentransplantierten (eine Analyse von 68 Autopsiefällen).