[Comparative study of 2 dosages of low molecular weight heparin, PK 10169, in the prevention of thromboembolic incidents during treatment of 103 femur neck fractures].
Results of this study in the elderly with fractures of femoral neck, in whom their exists an enhanced thrombogenic risk, showed that the dose of 40 mg per 24 hours as one or two divided injections of enoxaparine was as effective as adapted subcutaneous doses of calcium heparinate. It was also less iatrogenic and easier to manage (biological assays were of little use apart from platelet counts). Clinical evidence of pulmonary embolism, or mortality, were not observed in this series of 103 patients.
Barsotti
J
J
Service de Chirurgie générale et Traumatologie, Hôpital Trousseau, Chambray-les-Tours.
Dabo
B
B
Andreu
J
J
Favard
L
L
Rosset
P
P
Leroy
J
J
Delahousse
R
R
Alison
D
D
D000368:Aged; D000369:Aged, 80 and over; D004334:Drug Administration Schedule; D005260:Female; D005265:Femoral Neck Fractures / Q000601:surgery*; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000517:prevention & control*; D013923:Thromboembolism / Q000517:prevention & control*
D006495:Heparin, Low-Molecular-Weight
Etude comparative de deux posologies d'héparine de faible masse moléculaire PK 10,169 dans la prévention des accidents thrombo-emboliques au cours du traitement de 103 fractures du col du fémur.