title: Malacoplakia of the endometrium. An unusual case studied by electron microscopy and a review of the literature.
abstract: A rare case of malacoplakia (MKP) of the endometrium in an 88-year-old Japanese woman is presented. By light microscopy, typical Michaelis-Gutmann bodies (M-G bodies) could be identified. Electron microscopic findings revealed M-G bodies in various stages of development. These features suggested that M-G bodies were derived from round electron-dense granules that coalesced to form phagolysosomes. Early-stage M-G bodies were manifested as small, irregular, needle-shaped areas of calcification in phagolysosomes. The present paper reviews 6 cases of endometrial MKP, 5 of which have previously been reported in the literature, and this case being the sixth, to our knowledge.
authors.affiliation: Second Department of Pathology, Nagasaki University, School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kawai
authors.forename: K
authors.initials: K
authors.lastname: Fukuda
authors.forename: H
authors.initials: H
authors.lastname: Tsuchiyama
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004717:Endometrium / Q000473:pathology*; D005260:Female; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D008287:Malacoplakia / Q000188:drug therapy / Q000473:pathology*; D008854:Microscopy, Electron; D008875:Middle Aged; D011372:Progestins / Q000627:therapeutic use
chemical_list: D011372:Progestins