title: Copy choice illegitimate DNA recombination.
abstract: Precise excision of Tn10 and related transposons occurs by recombination between directly repeated 9 bp sequences that flank the transposon. The excision, which is a model for a class of illegitimate DNA recombination events, was stimulated 10(6) times by induction of single-stranded DNA synthesis, occurred during conversion of single-stranded DNA to double-stranded form, and entailed no transfer of physical material from parental to progeny molecules. We conclude that it occurred by copy choice DNA recombination and suggest that other illegitimate recombination events may occur by a similar mechanism.
authors.affiliation: Institut Jacques Monod T43, Paris, France.
authors.forename: D
authors.initials: D
authors.lastname: Brunier
authors.forename: B
authors.initials: B
authors.lastname: Michel
authors.forename: S D
authors.initials: SD
authors.lastname: Ehrlich
mesh_terms: D003090:Coliphages / Q000235:genetics*; D004261:DNA Replication; D004251:DNA Transposable Elements; D004277:DNA, Single-Stranded / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics*; D005838:Genotype; D010957:Plasmids; D011995:Recombination, Genetic; D014779:Virus Replication
chemical_list: D004251:DNA Transposable Elements; D004277:DNA, Single-Stranded