The nucleotide sequence of the peplomer gene of porcine transmissible gastroenteritis virus (TGEV): comparison with the sequence of the peplomer protein of feline infectious peritonitis virus (FIPV).
The amino acid sequence of the peplomer protein of transmissible gastroenteritis virus (TGEV) has been derived from the cloned cDNA sequence. The gene encodes a protein of 1447 amino acids with a molecular weight of 159 574. Comparison with the primary structure of the peplomer protein of feline infectious peritonitis virus (FIPV) (de Groot et al., 1987b) revealed one domain, from amino acids 1 to 274, in which the nucleotide homology was 39%, whereas in the second domain (from residues 275 to 1447) the homology was 93%.
Jacobs
L
L
Institute of Virology, Veterinary Faculty, State University, Utrecht, The Netherlands.
de Groot
R
R
van der Zeijst
B A
BA
Horzinek
M C
MC
Spaan
W
W
D000595:Amino Acid Sequence; D001483:Base Sequence; D003001:Cloning, Molecular; D003332:Coronaviridae / Q000235:genetics*; D005814:Genes, Viral; D006023:Glycoproteins / Q000235:genetics*; D008969:Molecular Sequence Data; D012689:Sequence Homology, Nucleic Acid; D005760:Transmissible gastroenteritis virus / Q000235:genetics*; D014759:Viral Envelope Proteins / Q000235:genetics*
D006023:Glycoproteins; D014759:Viral Envelope Proteins