title: Paget's disease of the breast with underlying carcinoma arising in systemic scleroderma.
abstract: A case is presented of Paget's disease of the breast with underlying infiltrating carcinoma arising in a 35-year-old woman with systemic scleroderma. The tumor arose in an area of the skin affected by the systemic scleroderma 4 years after the onset of her systemic disease. The possibility of a causal relationship between these two processes is discussed and a brief review of the literature is presented.
authors.affiliation: Department of Pathology, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
authors.forename: S
authors.initials: S
authors.lastname: Suster
authors.forename: M
authors.initials: M
authors.lastname: Ronnen
authors.forename: M
authors.initials: M
authors.lastname: Huszar
authors.forename: J J
authors.initials: JJ
authors.lastname: Bubis
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000209:etiology / Q000473:pathology*; D002277:Carcinoma / Q000209:etiology / Q000473:pathology*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology*; D005260:Female; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000209:etiology / Q000473:pathology*; D010144:Paget's Disease, Mammary / Q000209:etiology / Q000473:pathology*; D012595:Scleroderma, Systemic / Q000150:complications* / Q000473:pathology