title: Specific amino acid substitutions are not required for transformation by v-myb of avian myeloblastosis virus.
abstract: The protein product of the v-myb oncogene of avian myeloblastosis virus, p48v-myb, differs structurally in several ways from its normal cellular homolog, p75c-myb. We demonstrated that the 11 specific amino acid substitutions found in two independent molecular clones of this virus were not required for the transformation of myeloblasts by v-myb.
authors.affiliation: Department of Pathology, University of California, San Diego, La Jolla 92093.
authors.forename: U
authors.initials: U
authors.lastname: Stober-Grässer
authors.forename: J S
authors.initials: JS
authors.lastname: Lipsick
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001354:Avian Leukosis Virus / Q000502:physiology*; D009189:Avian Myeloblastosis Virus / Q000235:genetics / Q000502:physiology*; D002472:Cell Transformation, Viral; D002642:Chick Embryo; D006412:Hematopoietic Stem Cells; D020626:Oncogene Proteins v-myb; D012191:Retroviridae Proteins / Q000235:genetics / Q000502:physiology*
chemical_list: D020626:Oncogene Proteins v-myb; D012191:Retroviridae Proteins