title: Immunohistochemical identification of type I procollagen in tumour cells of scirrhous adenocarcinoma of the stomach.
abstract: Human gastric carcinomas were tested for their immunohistochemical reactivity with anti-type I procollagen antiserum. In all specimens of scirrhous carcinomas, staining of the tumour cells was strongly positive, while in medullary carcinomas staining of the tumour cells was generally poor. These results suggest that the tumour cells in scirrhous carcinomas produce collagen in their stroma.
authors.affiliation: Department of Internal Medicine, Sapporo Medical College, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Niitsu
authors.forename: N
authors.initials: N
authors.lastname: Ito
authors.forename: K
authors.initials: K
authors.lastname: Kohda
authors.forename: M
authors.initials: M
authors.lastname: Owada
authors.forename: K
authors.initials: K
authors.lastname: Morita
authors.forename: S
authors.initials: S
authors.lastname: Sato
authors.forename: N
authors.initials: N
authors.lastname: Watanabe
authors.forename: Y
authors.initials: Y
authors.lastname: Kohgo
authors.forename: I
authors.initials: I
authors.lastname: Urushizaki
mesh_terms: D002293:Adenocarcinoma, Scirrhous / Q000378:metabolism*; D004591:Electrophoresis, Polyacrylamide Gel; D005347:Fibroblasts / Q000378:metabolism; D006801:Humans; D007124:Immunoenzyme Techniques; D011347:Procollagen / Q000378:metabolism*; D013274:Stomach Neoplasms / Q000378:metabolism*
chemical_list: D011347:Procollagen