Classification of chronic granulomatous disease.
Chronic granulomatous disease is a heterogeneous disorder caused by at least three, and possibly four, types of mutations. Based on recent biochemical and molecular genetic data on this disease, a classification scheme and summary of the various forms of the disease are presented.
Curnutte
J T
JT
Department of Basic and Clinical Research, Research Institute of Scripps Clinic, La Jolla, California.
D003573:Cytochrome b Group / Q000172:deficiency / Q000235:genetics; D005260:Female; D005808:Genes, Recessive; D008040:Genetic Linkage; D006105:Granulomatous Disease, Chronic / Q000145:classification* / Q000235:genetics / Q000378:metabolism; D006801:Humans; D008297:Male; D009154:Mutation; D009247:NADH, NADPH Oxidoreductases / Q000172:deficiency / Q000378:metabolism; D019255:NADPH Oxidases; D009504:Neutrophils / Q000201:enzymology / Q000378:metabolism; D009580:Nitroblue Tetrazolium; D010101:Oxygen Consumption; D013481:Superoxides / Q000378:metabolism; D014960:X Chromosome
D003573:Cytochrome b Group; D013481:Superoxides; D009580:Nitroblue Tetrazolium; D009247:NADH, NADPH Oxidoreductases; D019255:NADPH Oxidases