title: Current management of low-risk metastatic gestational trophoblastic disease.
abstract: Low-risk metastatic gestational trophoblastic disease is highly curable with single-agent chemotherapy. Careful monitoring of the response to therapy is essential so that one can alter treatment when signs of drug resistance occur. Because some low-risk patients require complex chemotherapy and/or surgery before achieving remission, therapy should be directed by experienced clinicians at facilities where appropriate ancillary services are available.
authors.affiliation: Department of Obstetrics and Gynecology, Cornell University Medical College, New York, New York.
authors.forename: W B
authors.initials: WB
authors.lastname: Jones
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003609:Dactinomycin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008727:Methotrexate / Q000008:administration & dosage; D011247:Pregnancy; D012307:Risk Factors; D014328:Trophoblastic Neoplasms / Q000188:drug therapy / Q000556:secondary*; D014594:Uterine Neoplasms
chemical_list: D003609:Dactinomycin; D002955:Leucovorin; D008727:Methotrexate