title: HTLV-II and human lymphoproliferative disorders.
abstract: HTLV-II is a rarely encountered human retrovirus that has been linked to atypical presentations of hairy-cell leukemia, as well as a variety of T-cell malignancies. Recently, HTLV-II prevalence has increased in the United States, particularly in populations of intravenous drug abusers. Comparative study of HTLV-I and HTLV-II has allowed for important insights into the mechanisms of retroviral replication and T-cell transformation.
authors.affiliation: Department of Medicine, UCLA School of Medicine.
authors.forename: J D
authors.initials: JD
authors.lastname: Rosenblatt
authors.forename: I S
authors.initials: IS
authors.lastname: Chen
authors.forename: D W
authors.initials: DW
authors.lastname: Golde
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis; D017977:Deltaretrovirus / Q000235:genetics / Q000276:immunology; D006801:Humans; D007943:Leukemia, Hairy Cell / Q000382:microbiology*; D008213:Lymphocyte Activation; D014779:Virus Replication
chemical_list: D000914:Antibodies, Viral