title: Prevalence of cryptosporidiosis in patients undergoing endoscopy: evidence for an asymptomatic carrier state.
abstract: OBJECTIVE
  We sought to determine the presence of the parasite cryptosporidium in the duodenal aspirates of patients undergoing routine upper gastrointestinal endoscopy.
  
  
  METHODS
  The study consisted of 169 patients undergoing upper endoscopy or endoscopic retrograde cholangiopancreatography. Immunocompromised patients were not included in the study population. Samples were aspirated from the second portion of the duodenum. Biopsy specimens were also obtained. Three randomly passed stool samples were obtained from 75% of the patients who were found to have cryptosporidium in the duodenum.
  
  
  RESULTS
  Overall, cryptosporidium oocysts were identified in 12.7% of patients. There was no significant difference in the prevalence of the parasite in any subgroup of procedure or symptom complex. Half of those (46.7%) with positive aspirates had demonstrable cryptosporidium in stool samples, although none of the patients had diarrhea. No patient had detectable cryptosporidium in biopsy samples of the duodenum.
  
  
  CONCLUSIONS
  The findings suggest a surprisingly high asymptomatic carrier rate for cryptosporidium.
authors.affiliation: Department of Medicine (Gastroenterology) Columbia College of Physicians and Surgeons, New York 10032.
authors.forename: W G
authors.initials: WG
authors.lastname: Roberts
authors.forename: P H
authors.initials: PH
authors.lastname: Green
authors.forename: J
authors.initials: J
authors.lastname: Ma
authors.forename: M
authors.initials: M
authors.lastname: Carr
authors.forename: A M
authors.initials: AM
authors.lastname: Ginsberg
mesh_terms: D002353:Carrier State; D002760:Cholangiopancreatography, Endoscopic Retrograde; D003457:Cryptosporidiosis / Q000453:epidemiology* / Q000469:parasitology; D005243:Feces / Q000469:parasitology; D005260:Female; D005773:Gastroscopy; D006801:Humans; D008297:Male; D012189:Retrospective Studies