Identification of a receptor for the morphogen retinoic acid.
Analysis of complementary DNA encoding a novel gene product reveals striking similarity to the steroid and thyroid hormone receptors. Binding and transcription activational studies show it to be a receptor for the vitamin A-related morphogen retinoic acid.
Giguere
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V
Howard Hughes Medical Institute, Gene Expression Laboratory, Salk Institute for Biological Studies, San Diego, California 92037.
Ong
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ES
Segui
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Evans
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RM
D000595:Amino Acid Sequence; D001483:Base Sequence; D002352:Carrier Proteins / Q000502:physiology*; D004268:DNA-Binding Proteins / Q000502:physiology*; D005786:Gene Expression Regulation; D005796:Genes; D005809:Genes, Regulator; D008969:Molecular Sequence Data; D009024:Morphogenesis; D005810:Multigene Family; D018168:Receptors, Retinoic Acid; D011994:Recombinant Proteins; D014157:Transcription Factors / Q000502:physiology*
D002352:Carrier Proteins; D004268:DNA-Binding Proteins; D018168:Receptors, Retinoic Acid; D011994:Recombinant Proteins; D014157:Transcription Factors