Virus-induced thyroiditis.
Mice infected with reovirus type 1 developed a mild thyroiditis characterized by focal destruction of acinar tissue, infiltration of inflammatory cells, and autoantibodies to thyroglobulin and microsomal antigens. Thyroid involvement appears to be part of a more generalized virus-induced polyendocrine disease.
Srinivasappa
J
J
Laboratory of Oral Medicine, National Institute of Dental Research, Bethesda, Maryland 20892.
Garzelli
C
C
Onodera
T
T
Ray
U
U
Notkins
A L
AL
D000818:Animals; D001323:Autoantibodies / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D051379:Mice; D012087:Reoviridae; D012088:Reoviridae Infections / Q000276:immunology*; D013954:Thyroglobulin / Q000276:immunology; D013961:Thyroid Gland / Q000276:immunology; D013966:Thyroiditis / Q000382:microbiology*
D001323:Autoantibodies; D013954:Thyroglobulin