title: Fulminant Kaposi's sarcoma complicating long-term corticosteroid therapy.
abstract: Cutaneous Kaposi's sarcoma occurs rarely in patients receiving long-term corticosteroid therapy. The case of a rapidly progressive form of Kaposi's sarcoma occurring in a 29-year-old Palestinian woman with steroid-dependent Crohn's disease and familial Mediterranean fever is reported. Despite an extensive transfusion history, serologic and virologic studies failed to demonstrate exposure to the human immunodeficiency virus. Serologic and virologic evidence of concomitant cytomegalovirus infection, however, suggests possible pathogenic features similar to the acquired immunodeficiency syndrome-related form of Kaposi's sarcoma.
authors.affiliation: Department of Internal Medicine, Good Samaritan Medical Center, Phoenix, Arizona.
authors.forename: H O
authors.initials: HO
authors.lastname: Koop
authors.forename: M
authors.initials: M
authors.lastname: Holodniy
authors.forename: A F
authors.initials: AF
authors.lastname: List
mesh_terms: D000328:Adult; D003424:Crohn Disease / Q000188:drug therapy*; D003586:Cytomegalovirus Infections / Q000150:complications; D010505:Familial Mediterranean Fever / Q000188:drug therapy*; D005260:Female; D006679:HIV Seropositivity / Q000175:diagnosis; D006801:Humans; D011241:Prednisone / Q000009:adverse effects* / Q000627:therapeutic use; D012514:Sarcoma, Kaposi / Q000139:chemically induced* / Q000209:etiology; D012878:Skin Neoplasms / Q000139:chemically induced* / Q000209:etiology; D013997:Time Factors
chemical_list: D011241:Prednisone