Mechanism of transformation of 15(S)-hydroperoxyeicosatetraenoic acid to 15-series leukotrienes by purified porcine leukocyte 12-lipoxygenase.
Brash
A R
AR
Department of Pharmacology, Vanderbilt University Medical School, Nashville, Tennessee 37232.
Oates
J A
JA
Yokoyama
C
C
Yamamoto
S
S
D000818:Animals; D001092:Arachidonate 12-Lipoxygenase / Q000378:metabolism*; D001091:Arachidonate Lipoxygenases / Q000378:metabolism*; D001095:Arachidonic Acids / Q000096:biosynthesis / Q000378:metabolism*; D066298:In Vitro Techniques; D007962:Leukocytes / Q000201:enzymology; D017572:Leukotriene A4; D015289:Leukotrienes; D008054:Lipid Peroxides / Q000096:biosynthesis / Q000378:metabolism*; D013237:Stereoisomerism; D013552:Swine
C053872:14,15-dihydroperoxyeicosatetraenoic acid; D001095:Arachidonic Acids; D017572:Leukotriene A4; D015289:Leukotrienes; D008054:Lipid Peroxides; C025086:15-hydroperoxy-5,8,11,13-eicosatetraenoic acid; D001091:Arachidonate Lipoxygenases; D001092:Arachidonate 12-Lipoxygenase