[Quantitative CT studies of the lung in an animal experiment model of silicosis].
High resolution, narrow section CT examinations of the lungs were carried out on 21 Javanese macaques (five controls) shortly before the conclusion of 27 months exposure to quartz and/or high pressure. The aim was to establish morphometric CT data for differentiating and quantifying normal and abnormal findings. The results show that the technique has a high sensitivity for demonstrating the pathological lung changes. Final validation depends upon the use of respiratory physiology and biochemical, cytological, and histomorphometric data.
Rienmüller
R
R
Radiologische Klinik und Poliklinik, Universität München, Klinikum Grosshadern.
Schätzl
M
M
Kalender
W
W
Krombach
F
F
Fiehl
E
E
D000818:Animals; D004195:Disease Models, Animal; D008168:Lung / Q000000981:diagnostic imaging*; D008252:Macaca fascicularis; D012829:Silicosis / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
Quantitative CT-Untersuchungen der Lunge am tierexperimentellen Modell der Silikose.