title: [Focal nodular hyperplasia of the liver in 930 patients].
abstract: Analysis of 930 patients with focal nodular hyperplasia of the liver (FNH), including 23 seen by the authors, showed the following results: 82.2% of patients were female, 37.8% of these had taken female steroidal hormones. There was no preference for a particular lobe of the liver. 57.7% of FNH were subcapsular, 33.7% were intrahepatic and 8.8% were pedunculated. Average size was 5.9 cm, 80.8% of the patients were asymptomatic. In 93.5% (115 out of 123) a space-occupying lesion in the liver could be demonstrated by sonography. In 13%, second or multiple tumours were missed by sonography. CT without enhancement demonstrated FNH in 90.4% (94 out of 104 patients). A rapid, marked increase in density after contrast was seen in 64 out of 68 lesions (94.1%). Colloid scintigraphy showed normal uptake in 34.9% of patients. Hepato-biliary functional scintigraphy demonstrated 32 out of 35 lesions (91.4%). In 97.3% (183 out of 188) FNH was demonstrated by angiography, in 95.4% as a highly vascular tumour.
authors.affiliation: Institut für Klinische Strahlenkunde, Klinikum der Johannes-Gutenberg-Universität Mainz.
authors.forename: H
authors.initials: H
authors.lastname: Schild
authors.forename: K F
authors.initials: KF
authors.lastname: Kreitner
authors.forename: M
authors.initials: M
authors.lastname: Thelen
authors.forename: J
authors.initials: J
authors.lastname: Grönninger
authors.forename: M
authors.initials: M
authors.lastname: Weber
authors.forename: N
authors.initials: N
authors.lastname: Börner
authors.forename: J
authors.initials: J
authors.lastname: Störkel
authors.forename: D
authors.initials: D
authors.lastname: Eissner
mesh_terms: D000293:Adolescent; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006499:Hepatic Artery / Q000000981:diagnostic imaging; D006801:Humans; D006965:Hyperplasia / Q000175:diagnosis; D007098:Imino Acids; D007479:Iopamidol; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology*; D008113:Liver Neoplasms / Q000098:blood supply / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D007098:Imino Acids; D009942:Organometallic Compounds; D015609:Organotechnetium Compounds; C046767:technetium Tc 99m iminodiacetic acid; D007479:Iopamidol
vernacular_title: Fokal-noduläre Hyperplasie der Leber bei 930 Patienten.