[Reference values of n-propanol elimination].
Injections of increasing doses of n-propanol provoke blood concentration curves of exponential decays with dose dependent rate constants. The n-propanol-specific clearance is approximately 10 ml/min. It is determined by a Michaelis-Menten-metabolism (max. velocity of metabolizing: approximately 2.5 mg/l min; Michaelis-Menten-constant: approximately 10 mg/l) and is inhibited in the presence of ethanol.
Wehner
H D
HD
Schieffer
M C
MC
D000433:1-Propanol / Q000008:administration & dosage / Q000493:pharmacokinetics*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D008657:Metabolic Clearance Rate; D012016:Reference Values
D000433:1-Propanol
Kenndaten der n-Propanolelimination.