title: Frontonasal malformation as a field defect and in syndromic associations.
abstract: Several new "syndromes" have been described that have in common facial findings identical or similar to those seen in frontonasal malformation (FNM), previously termed frontonasal dysplasia. Some of those new syndromes are inherited, whereas FNM is an isolated finding. Thus there is a need for differentiation among those conditions. A review of the literature was undertaken to identify and classify the various reports that describe FNM as it occurs alone and in association with a syndrome.
authors.affiliation: Department of Oral Pathology and Genetics, School of Dentistry, University of Minnesota, Minneapolis.
authors.forename: H O
authors.initials: HO
authors.lastname: Sedano
authors.forename: R J
authors.initials: RJ
authors.lastname: Gorlin
mesh_terms: D002965:Classification; D003398:Craniosynostoses / Q000150:complications; D005124:Eye Abnormalities; D005624:Frontal Bone / Q000002:abnormalities*; D006801:Humans; D006972:Hypertelorism / Q000150:complications; D009666:Nose / Q000002:abnormalities*; D009958:Orofaciodigital Syndromes / Q000235:genetics; D012886:Skull / Q000002:abnormalities; D013576:Syndactyly / Q000150:complications; D013577:Syndrome