title: Cloning and characterization of the metallothionein-I gene from mouse LMTK cells.
abstract: A clone of about 14 kb containing the metallothionein MT-I gene and three repetitive sequences, was isolated from a genomic library of mouse LMTK DNA. The MT-I gene was functional. Transfected cells became cadmium resistant. Two of the three repetitive sequences were moderately repetitive while the other was closely related to the R family.
authors.affiliation: Département de Microbiologie, Faculté de Médecine, Université de Sherbrooke, Québec, Canada.
authors.forename: R
authors.initials: R
authors.lastname: Brzezinski
authors.forename: M
authors.initials: M
authors.lastname: Smorawinska
authors.forename: G
authors.initials: G
authors.lastname: Vézina
authors.forename: J
authors.initials: J
authors.lastname: Thibodeau
authors.forename: J P
authors.initials: JP
authors.lastname: Thirion
mesh_terms: D000818:Animals; D002104:Cadmium / Q000633:toxicity; D019256:Cadmium Chloride; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D003001:Cloning, Molecular; D004262:DNA Restriction Enzymes; D005796:Genes; D008668:Metallothionein / Q000235:genetics*; D051379:Mice; D009710:Nucleotide Mapping
chemical_list: D002104:Cadmium; D008668:Metallothionein; D004262:DNA Restriction Enzymes; D019256:Cadmium Chloride