[Determination of thermodynamic parameters of proflavine interaction with ribodinucleoside monophosphates CpG and PpC in an aqueous solution from data of proton magnetic resonance].
The temperature dependence of proton chemical shifts of proflavine in solution with isomeric ribodinucleoside monophosphates CpG and GpC has been studied. A scheme of calculation of thermodynamic parameters of dye aggregation and 1 : 1 and 1 : 2 complexes formation with dinucleotides has been proposed. The Gibbs' free energy, enthalpy and entropy of these reactions have been determined. It is concluded that hydrophobic interactions play an important part when 1 : 2 complex of proflavine with ribonucleosides is being formed.
Veselkov
A N
AN
Dymant
L N
LN
Baranovskiĭ
S F
SF
D000166:Acridines; D003562:Cytidine / Q000031:analogs & derivatives*; D003568:Cytidine Monophosphate / Q000031:analogs & derivatives; D003597:Cytosine Nucleotides; D015226:Dinucleoside Phosphates; D006150:Guanine Nucleotides; D006151:Guanosine / Q000031:analogs & derivatives*; D006157:Guanosine Monophosphate / Q000031:analogs & derivatives; D009682:Magnetic Resonance Spectroscopy; D011370:Proflavine; D012996:Solutions; D013816:Thermodynamics
D000166:Acridines; D003562:Cytidine; D003568:Cytidine Monophosphate; D003597:Cytosine Nucleotides; D015226:Dinucleoside Phosphates; D006150:Guanine Nucleotides; D006151:Guanosine; D006157:Guanosine Monophosphate; D011370:Proflavine; D012996:Solutions; C015772:CpG dinucleotide; C004804:guanylyl-(3',5')-cytidine
Opredelenie termodinamicheskikh parametrov vzaimodeĭstviia proflavina s ribodinukleozidmonofosfatami CpG i GpC v vodnom rastvore po dannym protonnogo magnitnogo rezonansa.