Blood transfusions and HIV infections (HIV1, HIV2/LAV2) in Ivory Coast.
Sera from 500 blood donors, 67 multiply-transfused children with sickle-cell anaemia and 320 healthy children who had not been transfused were tested for HIV1 and HIV2 antibodies. Amongst blood donors, 49 (9.8%) exhibited antibodies to retroviruses: 12 (2.4%) to HIV1, 17 (3.4%) to HIV2 and 20 (4%) to both HIV1 and HIV2. Fifteen (22.4%) of the 67 multiply-transfused children had retroviral antibodies: five (7.4%) to HIV1 four (6%) to HIV2 and six (9%) to both HIV1 and HIV2. In contrast, among 320 non-transfused children only two (0.62%) exhibited HIV1 infection. These results suggest that children with sickle-cell anaemia who have been repeatedly transfused, constitute a high risk group for HIV1 and HIV2 infections in Ivory Coast.
Ouattara
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SA
Institut Pasteur de Côte-D'Ivoire, Abidjan, Ivory Coast.
Gody
M
M
Rioche
M
M
Sangare
A
A
Meite
M
M
Akran
V
V
Aron
Y
Y
Sanogo
I
I
Ouattara
D
D
Saraka
K
K
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology / Q000635:transmission*; D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000276:immunology / Q000628:therapy; D000914:Antibodies, Viral / Q000032:analysis; D001782:Blood Donors; D002648:Child; D002675:Child, Preschool; D007560:Cote d'Ivoire; D004797:Enzyme-Linked Immunosorbent Assay; D006678:HIV / Q000276:immunology; D015483:HIV Antibodies; D006801:Humans; D007223:Infant; D012307:Risk Factors; D065227:Transfusion Reaction
D000914:Antibodies, Viral; D015483:HIV Antibodies