title: Expanded polytetrafluoroethylene prostheses as secondary blood access sites for hemodialysis: pathological findings in 29 excised grafts.
abstract: The popularity of expanded polytetrafluoroethylene (PTFE) arteriovenous fistulas for hemodialysis access is increasing. The low infection rate, low thrombogenicity and low body reactivity make it an important blood access for patients on routine hemodialysis. The authors examined 29 PTFE graft fistulas surgically excised from patients on hemodialysis for one or more of the following complications: infection 7, 2 with associated hemorrhage; thrombosis 9; aneurysm 11, 3 with associated thrombosis; stenosis 5, 3 with associated thrombosis; hemorrhage 4 and arterial steal 2. The explanted prostheses were reinforced Gore-tex in 20, Gore-tex thin wall in 1, Impra I in 4, Impra II in 3 and Vitagraft in 1. It was also noted that the implants failed in the short term mainly because of infection, in the medium term mainly because of thrombosis and stenosis, and in the long term usually because of aneurysm.
authors.affiliation: Biomaterials Unit, Hôpital St-François d'Assise, Québec, PQ.
authors.forename: S
authors.initials: S
authors.lastname: Canizales
authors.forename: J
authors.initials: J
authors.lastname: Charara
authors.forename: F
authors.initials: F
authors.lastname: Gill
authors.forename: R
authors.initials: R
authors.lastname: Guidoin
authors.forename: P E
authors.initials: PE
authors.lastname: Roy
authors.forename: P
authors.initials: P
authors.lastname: Bonnaud
authors.forename: G
authors.initials: G
authors.lastname: Laroche
authors.forename: M
authors.initials: M
authors.lastname: Batt
authors.forename: P
authors.initials: P
authors.lastname: Roy
authors.forename: M
authors.initials: M
authors.lastname: Marois
mesh_terms: D000328:Adult; D000368:Aged; D001132:Arm / Q000098:blood supply / Q000601:surgery; D001158:Arteries / Q000473:pathology; D001807:Blood Vessel Prosthesis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011138:Polytetrafluoroethylene / Q000627:therapeutic use*; D011475:Prosthesis Failure; D011677:Punctures; D006435:Renal Dialysis / Q000009:adverse effects / Q000379:methods*
chemical_list: D011138:Polytetrafluoroethylene