title: [Toxicity of different endodontic antiseptics].
abstract: The median lethal dose (LD 50) of endodontic antiseptics sodium hypochlorite, chloramine and chlorhexidine digluconate was determined in experiment on albino mice using the method described by Litchfield and Wilcoxon. Sodium hypochlorite and chloramine have shown a twice stronger toxic effect than chlorhexidine digluconate. The difference was significant.
authors.forename: W
authors.initials: W
authors.lastname: Klimm
authors.forename: L
authors.initials: L
authors.lastname: Krause
authors.forename: P
authors.initials: P
authors.lastname: Krause
authors.forename: J
authors.initials: J
authors.lastname: Wenzel
mesh_terms: D000818:Animals; D002700:Chloramines / Q000633:toxicity*; D002710:Chlorhexidine / Q000031:analogs & derivatives* / Q000633:toxicity; D051379:Mice; D012388:Root Canal Irrigants / Q000633:toxicity*; D012973:Sodium Hypochlorite / Q000633:toxicity*
chemical_list: D002700:Chloramines; D012388:Root Canal Irrigants; D012973:Sodium Hypochlorite; C030816:chloramine; C010882:chlorhexidine gluconate; D002710:Chlorhexidine
vernacular_title: Tierexperimentelle Untersuchungen zur Toxizität verschiedener Wurzelkanalantiseptika.