title: Virus-induced thyroiditis.
abstract: Mice infected with reovirus type 1 developed a mild thyroiditis characterized by focal destruction of acinar tissue, infiltration of inflammatory cells, and autoantibodies to thyroglobulin and microsomal antigens. Thyroid involvement appears to be part of a more generalized virus-induced polyendocrine disease.
authors.affiliation: Laboratory of Oral Medicine, National Institute of Dental Research, Bethesda, Maryland 20892.
authors.forename: J
authors.initials: J
authors.lastname: Srinivasappa
authors.forename: C
authors.initials: C
authors.lastname: Garzelli
authors.forename: T
authors.initials: T
authors.lastname: Onodera
authors.forename: U
authors.initials: U
authors.lastname: Ray
authors.forename: A L
authors.initials: AL
authors.lastname: Notkins
mesh_terms: D000818:Animals; D001323:Autoantibodies / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D051379:Mice; D012087:Reoviridae; D012088:Reoviridae Infections / Q000276:immunology*; D013954:Thyroglobulin / Q000276:immunology; D013961:Thyroid Gland / Q000276:immunology; D013966:Thyroiditis / Q000382:microbiology*
chemical_list: D001323:Autoantibodies; D013954:Thyroglobulin