Lymphocyte transformation test responses to cytomegalovirus in healthy adults from Britain and Iraq.
Lymphocyte transformation tests to CMV were carried out on young healthy adults from Britain and Iraq. Positive results were obtained in all of 28 seropositive British subjects as compared to 17 of 33 (51.5%) seropositive Iraqis; moreover, stimulation index values in the British group (mean 11.58) were significantly higher than in the Iraqi group (mean 2.84). Attempts to relate these differences to demographic characteristics, antibody response to CMV, including the response to early antigens, lymphoproliferative response to herpes simplex virus, and to phytohaemagglutinin and the presence of blocking factors were unrewarding.
Booth
J C
JC
Department of Virology, St. George's Hospital Medical School, University of London, England.
Rashid
S A
SA
Aziz
T A
TA
D000293:Adolescent; D000328:Adult; D000956:Antigens, Viral / Q000276:immunology; D002478:Cells, Cultured; D002648:Child; D002675:Child, Preschool; D003587:Cytomegalovirus / Q000276:immunology*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D007223:Infant; D007493:Iraq; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D012016:Reference Values; D018139:Simplexvirus / Q000276:immunology; D006113:United Kingdom
D000956:Antigens, Viral