Follow-up of superoxide production by phagocytes in whole blood of leukaemic patients during therapy.
The phagocyte function of granulocytes and monocytes of whole blood was measured as superoxide production in patients treated for acute nonlymphoblastic leukaemia. The results indicate that the antileukaemic protocol used in this study did not cause a decrease of the oxidative metabolism triggered by phagocytosis and by phorbol esters.
Todeschini
G
G
Istituto di Patologia Medica, Università di Verona, Italia.
Zeni
L
L
Bellavite
P
P
D000208:Acute Disease; D005500:Follow-Up Studies; D006801:Humans; D007938:Leukemia / Q000097:blood* / Q000188:drug therapy; D007958:Leukocyte Count / Q000379:methods; D010586:Phagocytes / Q000187:drug effects / Q000378:metabolism*; D013481:Superoxides / Q000096:biosynthesis / Q000097:blood*
D013481:Superoxides