Event-related potentials (P300) in myotonic dystrophy.
The P300 component of the auditory event-related potential in 8 patients with myotonic dystrophy was studied and compared with that of 13 healthy controls. Abnormalities of P300 (prolongation of the latency and/or decrease of the amplitude) were observed in 6. These observations imply that the function of cognitive and information processing are impaired in myotonic dystrophy.
Hanafusa
H
H
Department of Neuropsychiatry, Osaka Medical College, Takatsuki, Japan.
Motomura
N
N
Asaba
H
H
Sakai
T
T
Kawamura
H
H
D000161:Acoustic Stimulation; D000328:Adult; D005072:Evoked Potentials, Auditory; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009136:Muscular Dystrophies / Q000503:physiopathology*; D011930:Reaction Time / Q000502:physiology