[SPECT studies with 99mTc-HMPAO in Huntington's chorea patients].
Huntington's chorea is an autosomal dominant inherited disease with a chronic course and atrophy of the corpus striatum. PET examination shows reduced glucose metabolism in the caudate nucleus. We examined seven patients with Huntington's chorea by SPECT, using 99mTc-HMPAO. All patients had cortical defects of varying severity. In addition, five patients showed increased uptake in the region of the caudate nucleus. The specific tracer uptake due to the metabolic processes in the region of the caudate nucleus in Huntington's chorea is discussed.
Botsch
H
H
St. Josefskrankenhaus und Psychiatrische Universitätsklinik, Freiburg.
Oepen
G
G
Deuschl
G
G
Wolff
G
G
D002421:Caudate Nucleus / Q000000981:diagnostic imaging; D006801:Humans; D006816:Huntington Disease / Q000000981:diagnostic imaging*; D009942:Organometallic Compounds; D010091:Oximes; D012307:Risk Factors; D019690:Technetium Tc 99m Exametazime; D014055:Tomography, Emission-Computed
D009942:Organometallic Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime
SPECT-Untersuchungen mit 99mTc-HMPAO bei Patienten mit Huntingtonscher Chorea.