ATPase and acetylcholinesterase activities in erythrocyte membranes after incubation with glucose and in streptozotocin diabetic rats.
Enzyme activities of ATPases and acetylcholinesterase from isolated erythrocyte membranes (ghosts) were investigated before and after incubation with 50 mM glucose. Glucose incubation caused a time dependent loss of ATPase and acetylcholinesterase activities. Ghost enzyme activities in steptozotocin diabetic rats were found only insignificantly diminished.
Henschel
S
S
Institute of Biochemistry, Ernst Moritz Arndt University Greifswald, GDR.
Henschel
L
L
Lober
M
M
Krantz
S
S
D000110:Acetylcholinesterase / Q000097:blood*; D000251:Adenosine Triphosphatases / Q000097:blood*; D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000201:enzymology*; D004591:Electrophoresis, Polyacrylamide Gel; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000201:enzymology*; D005260:Female; D005947:Glucose / Q000494:pharmacology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D000254:Sodium-Potassium-Exchanging ATPase / Q000097:blood
D000110:Acetylcholinesterase; D000251:Adenosine Triphosphatases; D000254:Sodium-Potassium-Exchanging ATPase; D005947:Glucose