Detection of antibody to cytomegalovirus-induced early antigens and comparison with four serologic assays and presence of viruria in blood donors.
Five hundred blood donors were evaluated for cytomegalovirus (CMV) viruria, antibody to CMV early antigens (EA-ab), CMV seropositivity by two screening assays, and CMV-specific immunoglobulin M by two methods. Three donors were viruric, EA-ab positive, and seropositive; two viruric donors were immunoglobulin M positive.
Lentz
E B
EB
Research and Development Laboratory, American Red Cross Blood Services, Syracuse, New York 13202.
Dock
N L
NL
McMahon
C A
CA
Fiesthumel
S R
SR
Arnold
C B
CB
Lamberson
H V
HV
D000914:Antibodies, Viral / Q000032:analysis*; D000956:Antigens, Viral / Q000276:immunology*; D001782:Blood Donors; D003587:Cytomegalovirus / Q000276:immunology* / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000175:diagnosis*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D017874:Immediate-Early Proteins; D007075:Immunoglobulin M / Q000032:analysis; D007841:Latex Fixation Tests; D014556:Urine / Q000382:microbiology*
D000914:Antibodies, Viral; D000956:Antigens, Viral; D017874:Immediate-Early Proteins; D007075:Immunoglobulin M; C044582:immediate-early proteins, cytomegalovirus