title: The surgery of benign and malignant neoplasms adjacent to or involving the skull base.
abstract: A group of patients who have undergone resection of benign and malignant neoplasms, either adjacent to or through the skull base, were evaluated to determine whether the long-term results justify the risks of such surgery. A total of 37 patients underwent 55 operations in a 6.5-year period from December 1979 to July 1986 at The Ohio State University. An analysis of the operative, perioperative, and long-term complications demonstrates that surgery is well-tolerated. The disease-free interval and survival rates for both benign and malignant neoplasms are encouraging and demonstrate curative potential even for those patients presenting with recurrent malignancies extending through the base of the skull. The interdisciplinary approach evaluated in this study is an effective modality in the treatment of skull base tumors, conferring a favorable risk-benefit ratio.
authors.affiliation: Department of Otolaryngology, Ohio State University, Columbus.
authors.forename: D E
authors.initials: DE
authors.lastname: Schuller
authors.forename: M C
authors.initials: MC
authors.lastname: Hart
authors.forename: J H
authors.initials: JH
authors.lastname: Goodman
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005069:Evaluation Studies as Topic; D005260:Female; D006258:Head and Neck Neoplasms / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D012888:Skull Neoplasms / Q000601:surgery*