title: Maffucci's syndrome complicated by carcinoma of the breast, pituitary adenoma, and mediastinal hemangioma.
abstract: We have described a 39-year-old woman with Maffucci's syndrome, large mediastinal hemangiomas, infiltrating adenocarcinoma of the breast, and pituitary adenoma. This is the fifth reported case of Maffucci's syndrome with a coexistent pituitary adenoma, a frequency that cannot be explained by chance alone. There has been only one previously reported case in which the patient had a widened mediastinum, but the etiology was not discussed. Three of the four previously described patients with Maffucci's syndrome and a pituitary adenoma also had a proven or possible associated epithelial neoplasm. While this association is tenuous, it is considered worthy of comment.
authors.affiliation: Department of Laboratory Medicine, Wesley Medical Center, Wichita, Kan.
authors.forename: J V
authors.initials: JV
authors.lastname: Marymont
authors.forename: R F
authors.initials: RF
authors.lastname: Fisher
authors.forename: G E
authors.initials: GE
authors.lastname: Emde
authors.forename: T J
authors.initials: TJ
authors.lastname: Limbird
mesh_terms: D000236:Adenoma / Q000150:complications*; D000328:Adult; D001943:Breast Neoplasms / Q000150:complications*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000150:complications*; D004687:Enchondromatosis / Q000150:complications*; D005260:Female; D006391:Hemangioma / Q000150:complications*; D006801:Humans; D008479:Mediastinal Neoplasms / Q000150:complications*; D010009:Osteochondrodysplasias / Q000150:complications*; D010911:Pituitary Neoplasms / Q000150:complications*