title: Primary ovarian cancer.
abstract: Sixty-six patients with primary ovarian cancer were treated at National Taiwan University Hospital from 1981 to 1985. About 21% of the patients were in stage I, 18% in stage II, 50% in stage III and 11% in stage IV. The distribution of histologic types included 73% epithelial, 15% germ cell, 9% gonadal stroma, and 3% of non-specific mesenchymal origin. The ages at diagnosis ranged from 8 to 83 years. Peak incidence was noted between 50-59 years. Mean ages for epithelial, non-epithelial, and germ cell ovarian cancers were 52, 29, and 22 years, respectively. Most (47%) of the patients were treated by surgery plus chemotherapy. Complete surgical removal of the tumor mass was done for all 14 patients with stage I ovarian cancer. Bilateral salpingo-oophorectomy plus total abdominal hysterectomy was performed in 67% of stage II, 40% of stage III, and no stage IV case. The rates of occult bilaterality in the contralateral ovary for stage I to IV were 0%, 25%, 29% and 100%, respectively. Survival in ovarian cancer is a function of clinical stage and histologic type. The 2-year survival rates for stage I to stage IV were 71%, 67%, 33%, and 0%, respectively. The 2-year survival rate was 78% for non-epithelial ovarian cancer, and 26% for epithelial ovarian cancer.
authors.affiliation: Department of Obstetrics and Gynecology, National Taiwan University Hospital, College of Medicine, Taipei.
authors.forename: S N
authors.initials: SN
authors.lastname: Chow
authors.forename: Y P
authors.initials: YP
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D009373:Neoplasms, Germ Cell and Embryonal / Q000401:mortality / Q000473:pathology* / Q000628:therapy; D009375:Neoplasms, Glandular and Epithelial / Q000401:mortality / Q000473:pathology* / Q000628:therapy; D010051:Ovarian Neoplasms / Q000401:mortality / Q000473:pathology* / Q000628:therapy; D012189:Retrospective Studies