title: [Value of prophylactic irradiation to supraclavicular areas in small cell lung carcinoma--analysis of 104 patients].
abstract: A series of 104 patients with limited small cell lung carcinoma was treated by combination of chemotherapy and radiotherapy from August 1975 to July 1981. 104 patients were divided into three groups: prophylactic irradiation to supraclavicular areas (14 patients), non-prophylactic group (72 patients), non-prophylactic irradiation with positive supraclavicular lymph node metastasis after the treatment (18 patients). The 5 year survival rates of the three groups were 14%, 6% and 0%. Distant metastasis rates after the treatment were 36%, 52% and 61%, respectively. The supraclavicular lymph node metastasis rate after the treatment was higher in patients with intra-thoracic lymph node metastasis before the treatment (25%) than in those without this metastasis (0%). It is suggested that, for small cell lung cancer patients, especially with intra-thoracic lymph node metastasis before the treatment, prophylactic irradiation to the supraclavicular areas be valuable.
authors.affiliation: Cancer Institute, Chinese Academy of Medical Science, Beijing.
authors.forename: M
authors.initials: M
authors.lastname: Wang
authors.forename: W B
authors.initials: WB
authors.lastname: Yin
authors.forename: D F
authors.initials: DF
authors.lastname: Chen
authors.forename: X Z
authors.initials: XZ
authors.lastname: Gu
mesh_terms: D000328:Adult; D000368:Aged; D018288:Carcinoma, Small Cell / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies