Klinefelter's syndrome. An immunological disorder.
Immunological study was carried out in 10 cases of Klinefelter Syndrome against sperm antigen. Sperm antibody in serum was present in one of ten cases but cell mediated immunity on the basis of leukocyte migration inhibition test was positive in all the ten cases showing a strong link between chromosomal disorders and immunological tolerance.
Merchant
P C
PC
Department of Endocrinology, Topiwala National Medical College, Bombay/India.
Shahani
S M
SM
D001323:Autoantibodies / Q000032:analysis*; D001327:Autoimmune Diseases / Q000276:immunology*; D002464:Cell Migration Inhibition; D006801:Humans; D007108:Immune Tolerance; D007111:Immunity, Cellular; D007713:Klinefelter Syndrome / Q000276:immunology*; D008297:Male; D013094:Spermatozoa / Q000276:immunology*
D001323:Autoantibodies