title: Magnetic resonance imaging: comparison of four pulse sequences in assessing primary bone tumours.
abstract: A prospective magnetic resonance imaging (MRI) study was carried out in 13 patients (19 examinations) with primary bone tumours to assess the relative value of each of four pulse sequences in showing the extent and nature of the lesion. The four pulse sequences used were a T1-weighted spin-echo (SE544/44), a T2-weighted spin echo (SE1500/80), a short TI inversion recovery (STIR) (IR500/100/44), and a partial saturation (PS) (PS500/22) with field echo data collection. For soft tissue disease the combination of PS and STIR gave better definition of the boundary of the tumour than the more conventional T1 and T2-weighted spin echo sequences. For the demonstration of bone cortex, periosteal change and calcification, T1 and T2-weighted spin echo sequences were better. However, for calcified tissues, plain radiographs were better than either MRI combination. On the assumption that plain films will be available in all cases, PS and STIR sequences could therefore be substituted for T1 and T2-weighted spin echo sequences allowing an increase in soft tissue detectability for lesions in both red and yellow marrow.
authors.affiliation: Department of Diagnostic Radiology, Chaim Sheba Medical Centre, Tel Hashomer, Israel.
authors.forename: M
authors.initials: M
authors.lastname: Graif
authors.forename: J M
authors.initials: JM
authors.lastname: Pennock
authors.forename: J
authors.initials: J
authors.lastname: Pringle
authors.forename: D R
authors.initials: DR
authors.lastname: Sweetnam
authors.forename: A J
authors.initials: AJ
authors.lastname: Jelliffe
authors.forename: G M
authors.initials: GM
authors.lastname: Bydder
authors.forename: I R
authors.initials: IR
authors.lastname: Young
mesh_terms: D000293:Adolescent; D000328:Adult; D001853:Bone Marrow / Q000473:pathology; D001859:Bone Neoplasms / Q000175:diagnosis*; D002648:Child; D005269:Femur; D005870:Giant Cell Tumors / Q000175:diagnosis; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging; D011446:Prospective Studies; D013977:Tibia; D013997:Time Factors