title: The red nucleus activity in rats deprived of the inferior olivary complex.
abstract: The long-term effects of the inferior olive destruction on the red nucleus activity, were studied in the rat following injection of 3-acetylpyridine. As soon as the olivary activity was suppressed, the discharge of the rubral units drastically decreased. Then, they progressively recovered the control frequency during the first month, although a normal rubral activity was not restored up to 8 months. The hypothesis is advanced that the olivocerebellar system is essential to shape the activity of the rubrospinal pathway.
authors.affiliation: Unité INSERM U-161, Paris, France.
authors.forename: J M
authors.initials: JM
authors.lastname: Billard
authors.forename: C
authors.initials: C
authors.lastname: Batini
authors.forename: H
authors.initials: H
authors.lastname: Daniel
mesh_terms: D000818:Animals; D002529:Cerebellar Nuclei / Q000502:physiology; D009410:Nerve Degeneration / Q000187:drug effects; D009433:Neural Inhibition / Q000187:drug effects; D009434:Neural Pathways / Q000502:physiology; D009474:Neurons / Q000502:physiology; D009847:Olivary Nucleus / Q000502:physiology*; D011689:Purkinje Cells / Q000502:physiology; D011725:Pyridines / Q000494:pharmacology; D051381:Rats; D012012:Red Nucleus / Q000502:physiology*; D013116:Spinal Cord / Q000502:physiology; D009435:Synaptic Transmission / Q000187:drug effects
chemical_list: D011725:Pyridines; C010835:3-acetylpyridine