Colles' fracture and bone density of the ultradistal radius.
To determine whether Colles' fracture, generally considered a manifestation of postmenopausal osteoporosis, is associated with a decrease in bone density at the site of fracture, we measured bone mineral density of the ultradistal radius (UDR-BMD) by single-photon absorptiometry with computer-assisted image processing. In 119 normal women (ages 22-92 years), UDR-BMD decreased by 17% between ages 30 and 75 years. From UDR-BMD measurements in these normal women and in 40 women (ages 53-80 years) with Colles' fracture alone, a population-based analysis was made to estimate fracture risk at different values of UDR-BMD. Colles' fracture was uncommon at UDR-BMD greater than 0.40 g/cm2 (the "fracture threshold"). As bone density decreased below this level, fractures became more frequent (a "gradient of risk").
Eastell
R
R
Division of Endocrinology, Metabolism, and Internal Medicine, Mayo Clinic, Rochester, MN.
Riggs
B L
BL
Wahner
H W
HW
O'Fallon
W M
WM
Amadio
P C
PC
Melton
L J
LJ
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism; D003100:Colles' Fracture / Q000000981:diagnostic imaging / Q000378:metabolism*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D008903:Minerals / Q000032:analysis*; D011877:Radionuclide Imaging; D011884:Radius / Q000032:analysis* / Q000000981:diagnostic imaging; D011885:Radius Fractures / Q000378:metabolism*; D012044:Regression Analysis; D012307:Risk Factors
D008903:Minerals