title: [Dalargin--a basic means of intraoperative protection of a patient during correction of an atrial septal defect under conditions of artificial circulation: a new method of anesthesia].
abstract: The paper presents results of application of the Soviet synthetic neuropeptide Dalargin as a major agent of anesthesiologic protection in the correction of a secondary atrial septal defect under general artificial circulation. From the findings obtained from examinations of central and peripheral hemodynamic parameters and blood oxygen transport function it was concluded that the anesthesiological protection was adequate at all the stages of an operation. The authors also give data on the optimization of the afterload of the right ventricle and preload of the left ventricle under anesthesia in which dalargin was used by directly affecting the elasticity of pulmonary vessels. The nature of changes in the ventilation-perfusion relationships, in the postoperative period, in particular, also enables the author to recommend the preferable employment of the described method for anesthesia while correcting this type of heart disease.
authors.forename: B M
authors.initials: BM
authors.lastname: Shloznikov
authors.forename: V V
authors.initials: VV
authors.lastname: Likhvantsev
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Kuznetsov
authors.forename: A I
authors.initials: AI
authors.lastname: Peretrukhin
authors.forename: A L
authors.initials: AL
authors.lastname: Tverskoĭ
authors.forename: A V
authors.initials: AV
authors.lastname: Machulin
authors.forename: A N
authors.initials: AN
authors.lastname: Grin'ko
mesh_terms: D000293:Adolescent; D000328:Adult; D000758:Anesthesia / Q000379:methods*; D002648:Child; D004743:Enkephalin, Leucine / Q000494:pharmacology; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives*; D005112:Extracorporeal Circulation; D006343:Heart Septal Defects / Q000601:surgery*; D006801:Humans; D013565:Sympatholytics / Q000494:pharmacology*
chemical_list: D013565:Sympatholytics; D004743:Enkephalin, Leucine; D016308:Enkephalin, Leucine-2-Alanine; C040996:enkephalin-Leu, Ala(2)-Arg(6)-
vernacular_title: Dalargin--osnovnoe sredstvo intraoperatsionnoĭ zashchity bol'nogo pri korrektsii defekta mezhpredserdnoĭ peregorodki v usloviiakh iskusstvennogo krovoobrashcheniia: novyĭ metod anestezii.