title: The complete nucleotide sequence of the colicinogenic plasmid ColA. High extent of homology with ColE1.
abstract: The complete nucleotide sequence of the colicinogenic plasmid ColA has been determined. The plasmid DNA consists of 6720 bp (molecular weight 4.48 X 10(6]. Fifteen putative biological functions have been identified using the functional map previously determined. These include 11 genes and 3 DNA sites. Nine genes encode proteins of which 3 have been fully characterized. The replication region of ColA coding for RNAI and RNAII is highly homologous to that of ColE1 and Clo DF13. The same holds true for the site-specific recombination region containing palindromic symmetry and involved in stable maintenance of the plasmids. A high percentage of homology has been detected for putative mobility proteins encoded by ColA and ColE1. The exclusion proteins are also highly homologous.
authors.affiliation: Centre de Biochimie et de Biologie Moléculaire du CNRS, Marseille, France.
authors.forename: J
authors.initials: J
authors.lastname: Morlon
authors.forename: M
authors.initials: M
authors.lastname: Chartier
authors.forename: M
authors.initials: M
authors.lastname: Bidaud
authors.forename: C
authors.initials: C
authors.lastname: Lazdunski
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D003087:Colicins / Q000235:genetics*; D004262:DNA Restriction Enzymes; D004926:Escherichia coli / Q000235:genetics*; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D010957:Plasmids; D012689:Sequence Homology, Nucleic Acid
chemical_list: D003087:Colicins; D004262:DNA Restriction Enzymes