[The role of the modification of cyclic purine nucleotide molecule in the regulation of platelet acid glycosidase activity].
3'5'-cGMP activated beta-glucuronidase, beta-galactosidase, beta-glucosidase and N-acetyl-beta-glucosaminidase in blood platelets, while 2'3'-cGMP, 3,5'-cGMP, N2O2'-dipalmitoyl and 5'-GMP did not affect the activity of these glycosidases. The guanylate cyclase system appears to be involved in activation of blood platelets glycosidases since it is well known that 3'5'-cGMP activates the thrombocyte protein kinase.
Petrovich
Iu A
IuA
Trusova
N F
NF
D000818:Animals; D001792:Blood Platelets / Q000201:enzymology*; D006152:Cyclic GMP / Q000031:analogs & derivatives / Q000502:physiology*; D006026:Glycoside Hydrolases / Q000097:blood*; D006868:Hydrolysis; D010766:Phosphorylation; D051381:Rats
D006026:Glycoside Hydrolases; D006152:Cyclic GMP
Rol' modifikatsii molekuly purinovogo tsiklonukleotida v reguliatsii aktivnosti kisloĭ glikozidazy trombotsitov.