Effect of stress conditions on the course of trophozoite-induced Plasmodium yoelii nigeriensis in mice recently cured of a previous infection.
The effect of stress conditions on the course of trophozoite-induced Plasmodium yoelii nigeriensis in mice recently treated for a previous infection was studied. It was found that when the mice were infected with up to 5943 parasites within 6 days of treating a previous infection, no patent infection was recorded. However, an inoculum of 7924 parasites induced parasitaemia, with a long period of prepatency and a short course of infection before the parasites died out. None of the mice re-infected with the parasite, and maintained at different temperatures, was positive during the period of the experiment.
Oyerinde
J P
JP
Department of Medical Microbiology and Parasitology, College of Medicine of the University of Lagos, Nigeria.
Fagbenro-Beyioku
A F
AF
Jaji
B E
BE
D000818:Animals; D002738:Chloroquine / Q000627:therapeutic use; D008288:Malaria / Q000150:complications / Q000188:drug therapy / Q000276:immunology / Q000469:parasitology*; D008297:Male; D051379:Mice; D010967:Plasmodium yoelii; D013312:Stress, Physiological / Q000150:complications*; D013696:Temperature; D013997:Time Factors
D002738:Chloroquine