[Semisynthetic beta-lactam antibiotics. V. Metabolism in vitro of 6-[(R)-2-[3-(3,4-dihydroxybenzoyl)-3-(3-hydroxypropyl)-1- ureido]-2-phenylacetamido]penicillanic acid (AO-1100) and surveys on the metabolites].
Ohi
N
N
Ohsawa
Y
Y
Nehashi
T
T
Aoki
B
B
Okazaki
A
A
D000818:Animals; D000900:Anti-Bacterial Agents / Q000493:pharmacokinetics*; D001419:Bacteria / Q000187:drug effects; D002394:Catechol O-Methyltransferase / Q000378:metabolism; D004352:Drug Resistance, Microbial; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism; D008297:Male; D010397:Penicillanic Acid / Q000493:pharmacokinetics / Q000494:pharmacology / Q000031:analogs & derivatives; D011817:Rabbits; D051381:Rats; D011919:Rats, Inbred Strains
D000900:Anti-Bacterial Agents; C055252:AO 1100; D010397:Penicillanic Acid; D002394:Catechol O-Methyltransferase