title: A ouabain-displacing factor in normal pregnancy, pregnancy-induced hypertension and pre-eclampsia.
abstract: 1. A ouabain-displacing factor (ODF) was measured in the urine of non-pregnant, normotensive pregnant and hypertensive pregnant women by a receptor-binding assay with sodium, potassium-dependent adenosine triphosphatase. 2. Urinary ODF was significantly increased in normal pregnancy. 3. Greater increases were seen in pregnancy-induced hypertension and pre-eclampsia.
authors.affiliation: Service de Néphrologie, CHU, Amiens, France.
authors.forename: I
authors.initials: I
authors.lastname: Gregoire
authors.forename: D
authors.initials: D
authors.lastname: Roth
authors.forename: G
authors.initials: G
authors.lastname: Siegenthaler
authors.forename: P
authors.initials: P
authors.lastname: Fievet
authors.forename: N
authors.initials: N
authors.lastname: el Esper
authors.forename: H
authors.initials: H
authors.lastname: Favre
authors.forename: A
authors.initials: A
authors.lastname: Fournier
mesh_terms: D000328:Adult; D000450:Aldosterone / Q000097:blood; D002298:Cardenolides; D002395:Catecholamines / Q000097:blood; D004077:Digoxin; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000652:urine*; D045283:Natriuretic Agents / Q000652:urine*; D010953:Plasma Volume; D011225:Pre-Eclampsia / Q000097:blood / Q000652:urine*; D011247:Pregnancy / Q000097:blood / Q000652:urine*; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood / Q000652:urine*; D012083:Renin / Q000097:blood; D012503:Saponins; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors* / Q000652:urine; D014527:Uric Acid / Q000097:blood
chemical_list: D002298:Cardenolides; D002395:Catecholamines; D045283:Natriuretic Agents; D012503:Saponins; C034504:digoxin-like factors; D014527:Uric Acid; D000450:Aldosterone; D004077:Digoxin; D012083:Renin; D000254:Sodium-Potassium-Exchanging ATPase