A novel comprehensive opiate-receptor model.
A new, comprehensive opiate-receptor model based on calculations of possible events at the molecular level is proposed. Agonist versus antagonist action, ultra long-lasting activity and N-dealkylation accompanying receptor binding are included.
Kolb
V M
VM
Department of Chemistry, University of Wisconsin-Parkside, Kenosha 53141.
Snyder
J P
JP
D008958:Models, Molecular; D008959:Models, Neurological; D008968:Molecular Conformation; D009294:Narcotics / Q000378:metabolism*; D011487:Protein Conformation; D011957:Receptors, Opioid / Q000378:metabolism*
D009294:Narcotics; D011957:Receptors, Opioid