The relationship between dose and duration of action of intravenous flumazenil in reversing sedation induced by a continuous infusion of midazolam.
Dunton
A W
AW
Hoffmann-La Roche Clinical Pharmacology Unit, Newark Beth Israel Medical Center, New Jersey.
Schwam
E
E
Pitman
V
V
Leese
P
P
Siegel
J
J
D000328:Adult; D004305:Dose-Response Relationship, Drug; D005260:Female; D005442:Flumazenil / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008874:Midazolam / Q000494:pharmacology*; D011963:Receptors, GABA-A / Q000378:metabolism*; D012890:Sleep / Q000187:drug effects; D013997:Time Factors
D011963:Receptors, GABA-A; D005442:Flumazenil; D008874:Midazolam