title: [The use of zaditen in the combined treatment of allergic skin diseases in children].
abstract: Zaditen combined with local therapy and a rational hygienic and dietetic regimen has been administered to 158 children suffering from neurodermatitis (n = 142), eczema (n = 13), and strophulus (n = 3). The treatment has been effective in 148 (93.7%) children. Clinical remission has been achieved in 35 (22.2%) children, a considerable improvement in 87 (55.0%), and an improvement in 26 (16.5%). In 10 (6.3%) children no improvement has been observed. The improvement has been developing within the first fortnight of the treatment, but the drug has been continued for another week or two to stabilize the therapeutic effect. A follow-up of 102 children, effectively treated with zaditen, for 1-12 mos has shown relapses in 72 (70.6%) children, of these 7 relapses of medium severity and 1 severe relapse. Zaditen has been well tolerated by the children.
authors.forename: M E
authors.initials: ME
authors.lastname: Lipets
authors.forename: V N
authors.initials: VN
authors.lastname: Lopatko
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003131:Combined Modality Therapy; D003876:Dermatitis, Atopic / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007665:Ketotifen / Q000627:therapeutic use*; D008297:Male; D012008:Recurrence; D013997:Time Factors; D014581:Urticaria / Q000188:drug therapy*
chemical_list: D007665:Ketotifen
vernacular_title: Primenenie zaditena v kompleksnom lechenii allergicheskikh zabolevaniĭ kozhi u deteĭ.