Regulation of adenylate cyclase in a cultured neuronal cell line by marijuana constituents, metabolites of delta-9-tetrahydrocannabinol, and synthetic analogs having psychoactivity.
Howlett
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AC
Department of Pharmacology, St. Louis University School of Medicine, Missouri 63104.
D000067956:Adenylyl Cyclase Inhibitors; D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D002186:Cannabinoids / Q000494:pharmacology*; D013759:Dronabinol / Q000031:analogs & derivatives / Q000494:pharmacology; D008954:Models, Biological; D009474:Neurons / Q000187:drug effects* / Q000201:enzymology; D013329:Structure-Activity Relationship; D014407:Tumor Cells, Cultured
D000067956:Adenylyl Cyclase Inhibitors; D002186:Cannabinoids; D013759:Dronabinol; D000262:Adenylyl Cyclases