Cycloleucine competitively antagonizes the strychnine-insensitive glycine receptor.
Snell
L D
LD
Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston 77550.
Johnson
K M
KM
D000596:Amino Acids / Q000494:pharmacology*; D000818:Animals; D001224:Aspartic Acid / Q000031:analogs & derivatives / Q000378:metabolism; D001667:Binding, Competitive / Q000187:drug effects; D003515:Cycloleucine / Q000494:pharmacology*; D005998:Glycine / Q000378:metabolism; D066298:In Vitro Techniques; D008297:Male; D016202:N-Methylaspartate; D010622:Phencyclidine / Q000031:analogs & derivatives / Q000378:metabolism; D051381:Rats; D018009:Receptors, Glycine; D017981:Receptors, Neurotransmitter / Q000378:metabolism*; D013331:Strychnine / Q000494:pharmacology*
D000596:Amino Acids; D018009:Receptors, Glycine; D017981:Receptors, Neurotransmitter; D003515:Cycloleucine; D001224:Aspartic Acid; D016202:N-Methylaspartate; C012058:tenocyclidine; D013331:Strychnine; D010622:Phencyclidine; D005998:Glycine