[Antibodies against HTLV I in T-lymphoproliferative diseases of the skin].
The possibility that lymphoproliferative diseases may have a viral etiology has been discussed for many years. The first piece of evidence - in combination with convincing epidemiological data - was the detection of a virus of the HTLV group (HTLV I, ATLV) in patients with adult T-cell leukemia in Japan. There have been no comparable observations made in Europe. In 7 of 72 sera of patients with T-lymphoproliferative diseases in Central Europe, we were able to detect antibodies against HTLV I (ELISA and immunoblot), which might be an indication that retroviruses play a role in the etiology of these diseases.
von der Helm
D
D
Dermatologische Klinik und Poliklinik, Universität München.
von der Helm
K
K
Burg
G
G
Braun-Falco
O
O
Deinhardt
F
F
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000914:Antibodies, Viral / Q000032:analysis*; D017977:Deltaretrovirus / Q000276:immunology*; D005260:Female; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D012871:Skin Diseases / Q000276:immunology*; D013601:T-Lymphocytes
D000914:Antibodies, Viral
Antikörper gegen HTLV I bei T-lymphoproliferativen Erkrankungen der Haut.