title: [The question of medullomyoblastoma].
abstract: We report a 7 year old female presenting with a primary sarcoma of the frontal cortex, spinal cord metastases, and a cerebellar tumor. The latter was comprised of undifferentiated small cells and a component resembling rhabdomyosarcoma. On formal grounds it could be diagnosed either as medullomyoblastoma or rhabdomyosarcoma. At the ultrastructural level the tumor appeared more typical for a medullomyoblastoma but it seem highly improbable that both (rare) tumors appeared simultaneously by coincidence. Rather, we assume that we are dealing with a metastasis of the sarcoma with differentiation towards rhabdomyosarcoma. The apparent ability of a sarcoma to imitate morphological features of medullomyoblastoma in the cerebellum is further proof of the fact that nosological differentiation of both tumors remains a problem. Our findings did not corroborate the concept of medullomyoblastoma as a separate nosological entity.
authors.affiliation: Institut für Neuropathologie, Freien Universität Berlin.
authors.forename: S
authors.initials: S
authors.lastname: Patt
authors.forename: F
authors.initials: F
authors.lastname: Oppel
authors.forename: J
authors.initials: J
authors.lastname: Cervós-Navarro
mesh_terms: D001932:Brain Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D002528:Cerebellar Neoplasms / Q000473:pathology / Q000556:secondary* / Q000648:ultrastructure; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D005625:Frontal Lobe; D006801:Humans; D008527:Medulloblastoma / Q000473:pathology* / Q000556:secondary / Q000648:ultrastructure; D012208:Rhabdomyosarcoma / Q000473:pathology / Q000556:secondary / Q000648:ultrastructure; D012509:Sarcoma / Q000473:pathology* / Q000556:secondary / Q000648:ultrastructure; D013120:Spinal Cord Neoplasms / Q000473:pathology / Q000556:secondary / Q000648:ultrastructure
vernacular_title: Zur Frage des Medullomyoblastoms.