title: Scintigraphy of the salivary glands in Sjögen's syndrome.
abstract: Scintigraphy of the salivary glands with technetium-sodium pertechnetate (99mTc) was undertaken on 320 patients with oral dryness or connective tissue disease using a computer assisted method that gave quantitative results about the major salivary gland function. Compared with clinical and histological data, scintigraphy provides a sensitive method, even though it is not specific, for detecting minimal injuries to salivary glands in patients suspected of having Sjögen's syndrome. Moreover, it might differentiate between the Sjögen-like syndrome and the sequelae of radiotherapy in patients with bone marrow graft. Scintigraphy of the major salivary glands could therefore form part of the routine investigation of patients with Sjögen's syndrome.
authors.affiliation: Department of Nuclear Medicine, Hôpital Saint-Louis, Paris, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Arrago
authors.forename: J D
authors.initials: JD
authors.lastname: Rain
authors.forename: C
authors.initials: C
authors.lastname: Brocheriou
authors.forename: F
authors.initials: F
authors.lastname: Rocher
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010306:Parotid Gland / Q000000981:diagnostic imaging; D010862:Pilocarpine; D011877:Radionuclide Imaging; D012469:Salivary Glands / Q000000981:diagnostic imaging*; D012859:Sjogren's Syndrome / Q000000981:diagnostic imaging*; D013670:Sodium Pertechnetate Tc 99m; D013363:Submandibular Gland / Q000000981:diagnostic imaging; D014987:Xerostomia / Q000000981:diagnostic imaging
chemical_list: D010862:Pilocarpine; D013670:Sodium Pertechnetate Tc 99m