title: Malignant fibrous histiocytoma in a bonnet macaque (Macaca radiata).
abstract: Spontaneous sarcomas, not associated with an underlying disease, appear to be relatively rare in nonhuman primates. Since 1970, there have been few reported cases of naturally-occurring sarcomas of any kind in these species. A malignant histiocytoma and malignant fibrous histiocytoma have been described in a rhesus macaque and baboon, respectively. A malignant fibrous histiocytoma is defined as a sarcoma of varied pattern consisting of a mixture of histiocytic and fibroblastic elements. It is thought that the two cells types arise from a common precursor or that the fibroblastic elements are derived from the histiocytes. These tumors are relatively common in humans. Here we report a case of spontaneously-occurring malignant fibrous histiocytoma in an adult bonnet macaque.
authors.affiliation: Animal Resource Center, University of Colorado Health Sciences Center, Denver 80262.
authors.forename: P A
authors.initials: PA
authors.lastname: Skavlen
authors.forename: W C
authors.initials: WC
authors.lastname: Speers
authors.forename: R R
authors.initials: RR
authors.lastname: Peterson
authors.forename: J O
authors.initials: JO
authors.lastname: Stevens
authors.forename: M L
authors.initials: ML
authors.lastname: Reite
mesh_terms: D000818:Animals; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology / Q000556:secondary / Q000662:veterinary*; D008175:Lung Neoplasms / Q000556:secondary / Q000662:veterinary*; D008251:Macaca; D008255:Macaca radiata; D008297:Male; D008992:Monkey Diseases / Q000473:pathology*; D009364:Neoplasm Recurrence, Local; D012878:Skin Neoplasms / Q000473:pathology / Q000662:veterinary*