Consequences of fluid loss in patients treated with ACE inhibitors.
Three patients are described in whom haemodynamic collapse and acute renal failure occurred following intercurrent gastrointestinal fluid loss during treatment with an angiotensin converting-enzyme inhibitor. The possible consequences of blockade of the formation of angiotensin II during fluid loss are discussed.
McMurray
J
J
Royal Infirmary, Edinburgh, UK.
Matthews
D M
DM
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000368:Aged; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects*; D002216:Captopril / Q000009:adverse effects; D003681:Dehydration / Q000139:chemically induced*; D003967:Diarrhea / Q000139:chemically induced; D004656:Enalapril / Q000009:adverse effects; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged
D000806:Angiotensin-Converting Enzyme Inhibitors; D004656:Enalapril; D002216:Captopril