[Imported leishmaniasis of dogs: clinical aspects, diagnosis and therapy with Na stibogluconate (Pentostam)].
Between May 1982 and September 1986 13 dogs with leishmaniosis received inpatient treatment with Pentostam at the I. Medical Department of the Veterinary Faculty, University of Munich. Predominant clinical signs of all animals were alterations of the skin and hair coat and additionally they showed a reduced general condition (4 dogs), loss of weight (3 dogs), diarrhea (5 dogs) and pain during movements. In the blood samples taken prior treatment in 9 dogs there was an increased total protein concentration. 5 dogs had changes in the red and 4 dogs in the white blood count. Thrombocytopenia occurred in 6 dogs. Leishmaniosis was diagnosed clinically and serologically (IFAT). Na-Stibogluconate (Pentostam) was used for the treatment at a dosage of 10 or 20 mg/kg on 10 or 14 consecutive days. Two dogs died during an early stage of therapy. 6 dogs were discharged as clinically cured after a single or repeated treatment course(s).
Reusch
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Medizinischen Tierklinik, Ludwig-Maximilians-Universität München.
Reiter
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I
D000818:Animals; D000967:Antimony Sodium Gluconate / Q000627:therapeutic use*; D001798:Blood Proteins / Q000032:analysis; D004283:Dog Diseases / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy*; D004285:Dogs; D004906:Erythrocyte Count / Q000662:veterinary; D005942:Gluconates / Q000627:therapeutic use*; D007898:Leishmaniasis, Visceral / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D007958:Leukocyte Count / Q000662:veterinary
D001798:Blood Proteins; D005942:Gluconates; D000967:Antimony Sodium Gluconate
Die importierte Hundeleishmaniose: Erfahrungen zu Klinik, Diagnostik und Therapie mit Na-Stibogluconat (Pentostam).