title: [Controlled pulmonary arterial hypotension using obsidan and sodium nitroprusside in the early period following closed mitral commissurotomy].
abstract: Controlled pulmonary hypotension using sodium nitroprusside in combination with propranolol was employed in 23 patients in the early postoperative period after closed mitral valvulotomy. Pulmonary circulation, gas exchange and some nonrespiratory pulmonary functions have been assessed. It has been shown that increased blood levels of serotonin, histamine, noradrenaline and especially cyclic adenosine monophosphate play an essential role in the pathogenesis of postoperative pulmonary vasoconstriction.
authors.forename: G N
authors.initials: GN
authors.lastname: Gimmel'farb
authors.forename: V E
authors.initials: VE
authors.lastname: Kleĭnerman
authors.forename: N M
authors.initials: NM
authors.lastname: Gerasimov
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005292:Ferricyanides; D006801:Humans; D007023:Hypotension, Controlled; D008297:Male; D008875:Middle Aged; D008946:Mitral Valve Stenosis / Q000601:surgery*; D009599:Nitroprusside / Q000627:therapeutic use*; D011184:Postoperative Period; D011433:Propranolol / Q000627:therapeutic use*; D011651:Pulmonary Artery
chemical_list: D005292:Ferricyanides; D009599:Nitroprusside; D011433:Propranolol
vernacular_title: Upravliaemaia legochno-arterial'naia gipotenziia obzidanom i nitroprussidom natriia v blizhaĭshem periode posle zakrytoĭ mitral'noĭ komissurotomii.