Characterization of a T-lymphocyte Epstein-Barr virus/C3d receptor (CD21).
The Epstein-Barr virus/C3d receptor (EBVR-CR2) was detected on three T-lymphoblastoid cell lines. The apparent Mrs of purified EBVR-CR2 of T-cell and B-cell origin were identical. The N-terminal amino acid sequence from the T-cell EBVR-CR2 confirmed the placement of this receptor in a multigene family of complement regulatory proteins. All EBVR-CR2-positive T-cell lines were T6 and T4-T8 antigen positive.
Fingeroth
J D
JD
Division of Infectious Diseases, Dana-Farber Cancer Institue, Boston, Massachusetts 02115.
Clabby
M L
ML
Strominger
J D
JD
D000595:Amino Acid Sequence; D002460:Cell Line; D005434:Flow Cytometry; D005814:Genes, Viral; D004854:Herpesvirus 4, Human / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D011951:Receptors, Complement / Q000235:genetics*; D017464:Receptors, Complement 3d; D011991:Receptors, Virus / Q000235:genetics*; D012091:Repetitive Sequences, Nucleic Acid; D013601:T-Lymphocytes / Q000382:microbiology*
D011951:Receptors, Complement; D017464:Receptors, Complement 3d; D011991:Receptors, Virus