title: Subclinical measles infection in vaccinated seropositive individuals in arctic Greenland.
abstract: Measles vaccination was performed in the arctic district of Scoresbysund, Greenland in 1968, which had never been exposed to natural measles. More than 90% of the total population was vaccinated and a 94-100% seroconversion was obtained. During a serological survey to examine the immunity status of the vaccinees, it was discovered that a temporary increase in measles antibodies took place in the majority of the population 2-4 years after the vaccination. This was not accompanied by clinically observed measles. Most likely, it was due to an inapparent measles infection in a population considered highly immune after vaccination.
authors.affiliation: Institute of Medical Microbiology, University of Copenhagen, Denmark.
authors.forename: I R
authors.initials: IR
authors.lastname: Pedersen
authors.forename: C H
authors.initials: CH
authors.lastname: Mordhorst
authors.forename: G
authors.initials: G
authors.lastname: Glikmann
authors.forename: H
authors.initials: H
authors.lastname: von Magnus
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D001110:Arctic Regions; D004797:Enzyme-Linked Immunosorbent Assay; D006116:Greenland; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D008457:Measles / Q000276:immunology*; D008458:Measles Vaccine / Q000276:immunology*; D012698:Serologic Tests; D013997:Time Factors; D014611:Vaccination
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D008458:Measles Vaccine