title: [Antiviral activity of a chemical contraceptive (nonoxynol-9)].
abstract: The aim of this study was to evaluate, in vitro, the antiviral activity of a chemical contraceptive (Nonoxynol-9). The results have demonstrated that such a compound is able to inhibit the infectivity of enveloped viruses. It seems that the activity of this contraceptive is due to the lesion of the envelope.
authors.affiliation: Istituto di Virologia dell'Università degli Studi di Milano.
authors.forename: M
authors.initials: M
authors.lastname: Barbi
authors.forename: G L
authors.initials: GL
authors.lastname: Bertoli
authors.forename: G
authors.initials: G
authors.lastname: Miceli
mesh_terms: D002460:Cell Line; D003270:Contraceptive Agents / Q000494:pharmacology*; D006801:Humans; D017137:Nonoxynol; D017955:Poliovirus / Q000187:drug effects; D011092:Polyethylene Glycols / Q000494:pharmacology*; D012136:Respiratory Syncytial Viruses / Q000187:drug effects; D018139:Simplexvirus / Q000187:drug effects; D013089:Spermatocidal Agents / Q000494:pharmacology*; D014780:Viruses / Q000187:drug effects*
chemical_list: D003270:Contraceptive Agents; D013089:Spermatocidal Agents; D017137:Nonoxynol; D011092:Polyethylene Glycols
vernacular_title: Attività antivirale di un contraccettivo chimico (nonoxynol-9).