Paget's disease of the breast with underlying carcinoma arising in systemic scleroderma.
A case is presented of Paget's disease of the breast with underlying infiltrating carcinoma arising in a 35-year-old woman with systemic scleroderma. The tumor arose in an area of the skin affected by the systemic scleroderma 4 years after the onset of her systemic disease. The possibility of a causal relationship between these two processes is discussed and a brief review of the literature is presented.
Suster
S
S
Department of Pathology, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
Ronnen
M
M
Huszar
M
M
Bubis
J J
JJ
D000328:Adult; D001943:Breast Neoplasms / Q000209:etiology / Q000473:pathology*; D002277:Carcinoma / Q000209:etiology / Q000473:pathology*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology*; D005260:Female; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000209:etiology / Q000473:pathology*; D010144:Paget's Disease, Mammary / Q000209:etiology / Q000473:pathology*; D012595:Scleroderma, Systemic / Q000150:complications* / Q000473:pathology