Phosphatase and phospholipase activity in Alzheimer brain tissues.
There is a reduction in the ability of Alzheimer brain tissue homogenates to release choline from both lecithin and phosphorylcholine. This suggests that dietary treatment with choline or lecithin supplements will not be useful.
Kanfer
J N
JN
Department of Biochemistry, Faculty of Medicine, University of Manitoba, Winnipeg, Canada.
McCartney
D G
DG
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000378:metabolism*; D002794:Choline / Q000378:metabolism*; D006801:Humans; D008875:Middle Aged; D010740:Phospholipases / Q000378:metabolism; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism; D051381:Rats
D010740:Phospholipases; D010744:Phosphoric Monoester Hydrolases; D002794:Choline