title: [Markers of the hepatitis B virus in the blood serum and liver tissue in chronic diffuse diseases].
abstract: It is shown that the activity of the disease depends on the localisation of HBsAg and HBcAg in the hepatocyte and on the reaction of the delayed hypersensitivity (RDH) to HBsAg and liver-specific lipoprotein (LSL). RDH to HBsAg, LSL and a diffuse localisation of HBsAg in the hepatocyte cytoplasm are observed in the non-active chronic diffuse liver disease while the marginal or membraneous localisation of HBsAg which is frequently combined with HBcAg in nuclei and RDH to HBsAg and LSL are found in the active forms of chronic liver diseases.
authors.forename: Kh Kh
authors.initials: KhKh
authors.lastname: Mansurov
authors.forename: G K
authors.initials: GK
authors.lastname: Mirodzhov
authors.forename: L I
authors.initials: LI
authors.lastname: Tkalicheva
authors.forename: N S
authors.initials: NS
authors.lastname: Asfandiiarova
mesh_terms: D015415:Biomarkers / Q000032:analysis; D001706:Biopsy; D002908:Chronic Disease; D006510:Hepatitis B Antibodies / Q000032:analysis; D006512:Hepatitis B Core Antigens / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006515:Hepatitis B virus / Q000276:immunology*; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology / Q000473:pathology; D008074:Lipoproteins / Q000276:immunology; D008099:Liver / Q000276:immunology* / Q000473:pathology; D008107:Liver Diseases / Q000276:immunology* / Q000473:pathology; D008565:Membrane Proteins; D011506:Proteins / Q000276:immunology
chemical_list: D015415:Biomarkers; D006510:Hepatitis B Antibodies; D006512:Hepatitis B Core Antigens; D006514:Hepatitis B Surface Antigens; D008074:Lipoproteins; D008565:Membrane Proteins; D011506:Proteins
vernacular_title: Izuchenie markerov virusa gepatitia B v syvorotke krovi i tkani pecheni pri khronicheskikh diffuznykh zabolevaniiakh.