title: A quantitative analysis of the spatial relationships of grouped microcalcifications demonstrated on xeromammography in benign and malignant breast disease.
abstract: The mammograms of 444 patients who had a breast biopsy leading to a definitive histological diagnosis were reviewed. In 21 cases (4.7%) grouped microcalcifications were identified as the only mammographic abnormality. These groups of microcalcifications were analysed to determine whether there was any quantitative difference between benign and malignant lesions with respect to a shape parameter of the group, the spatial frequency of the particles and neighbour-to-neighbour relationships of the particles. This analysis did not reveal any significant difference between the spatial relationships of the grouped microcalcifications found in benign and malignant breast disease.
authors.affiliation: Department of Diagnostic Radiology, Royal Marsden Hospital, London.
authors.forename: D M
authors.initials: DM
authors.lastname: Hansell
authors.forename: J C
authors.initials: JC
authors.lastname: Cooke
authors.forename: C A
authors.initials: CA
authors.lastname: Parsons
authors.forename: S H
authors.initials: SH
authors.lastname: Evans
authors.forename: D R
authors.initials: DR
authors.lastname: Dance
authors.forename: J M
authors.initials: JM
authors.lastname: Bliss
authors.forename: I
authors.initials: I
authors.lastname: Llesley
mesh_terms: D001706:Biopsy; D001941:Breast Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D002114:Calcinosis / Q000000981:diagnostic imaging* / Q000473:pathology; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000000981:diagnostic imaging* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008327:Mammography; D011237:Predictive Value of Tests; D014984:Xeromammography