title: Heterophyle antibodies causing false positive radio-immunoassay results. A case report.
abstract: A case report of falsely elevated serum hormone values measured by radio-immunoassay (RIA) is described. The radio-immunoassays concerned have a first antibody raised in rabbits and mostly a separation technique based on a second antibody-solid phase system. The presence of heterophyle (anti-rabbit) antibodies in patients' serum is proved.
authors.affiliation: University Hospital and Medical School, Brussel, Belgium.
authors.forename: J
authors.initials: J
authors.lastname: Smitz
authors.forename: W
authors.initials: W
authors.lastname: Foulon
authors.forename: J
authors.initials: J
authors.lastname: Heip
authors.forename: N
authors.initials: N
authors.lastname: Naaktgeboren
authors.forename: A
authors.initials: A
authors.lastname: Van Steirteghem
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000032:analysis; D000328:Adult; D000818:Animals; D000906:Antibodies / Q000276:immunology*; D003429:Cross Reactions; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D011247:Pregnancy; D011259:Pregnancy Tests, Immunologic / Q000379:methods*; D011817:Rabbits; D011863:Radioimmunoassay
chemical_list: D000906:Antibodies; D000324:Adrenocorticotropic Hormone