title: [Immunological and hormono-metabolic indices in trophoblastic disease].
abstract: Certain immunologic and hormono-metabolic indexes were studied in patients with hydatidiform mole and uterine choriocarcinoma. Changes in T- and B-lymphocyte ratio were observed: B-lymphocyte levels were abnormally high in hydatidiform mole while those of T-lymphocytes-low in choriocarcinoma. Blastogenic response of lymphocytes in trophoblastic disease matched the mean values in healthy females. No pronounced metabolic changes were registered in cases of trophoblastic disease (who are generally young). It was concluded that cellular immunity suppression is not associated with fat-carbohydrate metabolism disturbances in hydatidiform mole and choriocarcinoma of the uterus.
authors.forename: T E
authors.initials: TE
authors.lastname: Poroshina
authors.forename: A V
authors.initials: AV
authors.lastname: Semenovskiĭ
authors.forename: Iu F
authors.initials: IuF
authors.lastname: Bobrov
authors.forename: V B
authors.initials: VB
authors.lastname: Gamaiunova
authors.forename: M N
authors.initials: MN
authors.lastname: Ostroumova
mesh_terms: D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology; D002822:Choriocarcinoma / Q000276:immunology* / Q000378:metabolism; D003907:Dexamethasone; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D008055:Lipids / Q000097:blood; D008213:Lymphocyte Activation; D008875:Middle Aged; D011247:Pregnancy; D013601:T-Lymphocytes / Q000276:immunology; D014328:Trophoblastic Neoplasms / Q000276:immunology* / Q000378:metabolism; D014594:Uterine Neoplasms / Q000276:immunology* / Q000378:metabolism
chemical_list: D008055:Lipids; D003907:Dexamethasone
vernacular_title: Immunologicheskie i gormonal'no-metabolicheskie pokazateli pri trofoblasticheskoĭ bolezni.