Squamous carcinoma arising in a giant peri-anal condyloma associated with human papillomavirus types 6 and 11.
A case is reported of squamous carcinoma of the peri-anal region arising in a giant condyloma. In situ DNA hybridization showed human papillomavirus (HPV) types 6 and 11. These HPV types are commonly demonstrated in ano-genital condylomas but have not previously been reported in association with malignant change at this site.
Wells
M
M
Department of Pathology, University of Leeds, UK.
Robertson
S
S
Lewis
F
F
Dixon
M F
MF
D000694:Anal Gland Neoplasms / Q000150:complications*; D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000209:etiology*; D003218:Condylomata Acuminata / Q000150:complications*; D004247:DNA / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009693:Nucleic Acid Hybridization; D027383:Papillomaviridae / Q000145:classification; D014412:Tumor Virus Infections / Q000150:complications*
D004247:DNA