Synthesis, binding studies, and structure-activity relationships of 1-aryl-and 2-aryl[1]benzopyranopyrazol-4-ones, central benzodiazepine receptor ligands.
Colotta
V
V
Dipartimento di Scienze Farmaceutiche, Università di Firenze, Italy.
Cecchi
L
L
Filacchioni
G
G
Melani
F
F
Palazzino
G
G
Martini
C
C
Giannaccini
G
G
Lucacchini
A
A
D000818:Animals; D001578:Benzopyrans / Q000138:chemical synthesis* / Q000494:pharmacology; D001921:Brain / Q000378:metabolism; D002417:Cattle; D002462:Cell Membrane / Q000378:metabolism; D005445:Flunitrazepam / Q000378:metabolism; D007202:Indicators and Reagents; D008024:Ligands; D011719:Pyrazines / Q000138:chemical synthesis* / Q000494:pharmacology; D011720:Pyrazoles / Q000138:chemical synthesis; D047069:Pyrazolones; D011963:Receptors, GABA-A / Q000187:drug effects / Q000378:metabolism*; D013329:Structure-Activity Relationship
D001578:Benzopyrans; D007202:Indicators and Reagents; D008024:Ligands; D011719:Pyrazines; D011720:Pyrazoles; D047069:Pyrazolones; D011963:Receptors, GABA-A; C038362:pyrazolone; D005445:Flunitrazepam