title: DNA cleavage based on high voltage electric pulse.
abstract: A high voltage electric pulse was applied to DNA cleavage. The DNA cleavage reaction was dependent on the voltage amplitude, pulse number and pulse width. Radical scavengers and ESR data indicated the possibility that active species such as OH radical were strongly related to DNA cleavage.
authors.affiliation: Research Laboratory of Resources Utilization, Tokyo Institute of Technology, Yokohama, Japan.
authors.forename: E
authors.initials: E
authors.lastname: Tamiya
authors.forename: Y
authors.initials: Y
authors.lastname: Nakajima
authors.forename: H
authors.initials: H
authors.lastname: Kamioka
authors.forename: M
authors.initials: M
authors.lastname: Suzuki
authors.forename: I
authors.initials: I
authors.lastname: Karube
mesh_terms: D004247:DNA; D004279:DNA, Viral; D004563:Electrochemistry; D004578:Electron Spin Resonance Spectroscopy; D004720:Endonucleases; D008970:Molecular Weight; D015719:Single-Strand Specific DNA and RNA Endonucleases
chemical_list: D004279:DNA, Viral; D004247:DNA; D004720:Endonucleases; D015719:Single-Strand Specific DNA and RNA Endonucleases