Alkalosis and renal excretion of ammonia by rat kidney.
Upon sulfate administration, UpH falls more in alkalotic rats than in controls. Alkalosis can lead to a reduction in UNH3 V at highly acidic urine. The significance of this process is doubtful at UpH ranging from about 6 to 7. At lower UpH less NH3 would be excreted, thereby less H+ would be trapped in urine and some acid would be conserved.
Solomon
S
S
University of New Mexico School of Medicine, Albuquerque 87131.
D000471:Alkalosis / Q000139:chemically induced / Q000503:physiopathology*; D000641:Ammonia / Q000652:urine*; D000818:Animals; D001639:Bicarbonates; D006863:Hydrogen-Ion Concentration; D007668:Kidney / Q000503:physiopathology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012964:Sodium; D017693:Sodium Bicarbonate; D014556:Urine
D001639:Bicarbonates; D000641:Ammonia; D017693:Sodium Bicarbonate; D012964:Sodium