Effect of fiber supplements on the apparent absorption of pharmacological doses of riboflavin.
The effect of dietary fiber from wheat bran and psyllium gum on the apparent absorption of riboflavin was studied in 12 healthy women. The test fiber was consumed in crackers that contained approximately 7.5 gm fiber from psyllium gum, wheat bran, or a combination of the two sources. Each subject was given a riboflavin load test after consuming one of the three different fiber supplements or a control supplement that contained 1.3 gm fiber. Fractional urine collections were made for 24 hours, and riboflavin was measured by fluorometric techniques. The psyllium gum and combination supplements reduced the 24-hour apparent absorption of riboflavin from 31.8% to 25.4% and 26.1%, respectively (p less than .01). No effect of the wheat bran supplement on riboflavin was detected.
Roe
D A
DA
Division of Nutritional Sciences, Cornell University, Ithaca, New York.
Kalkwarf
H
H
Stevens
J
J
D000042:Absorption; D000328:Adult; D004043:Dietary Fiber / Q000494:pharmacology*; D005260:Female; D006801:Humans; D011620:Psyllium / Q000494:pharmacology*; D012256:Riboflavin / Q000493:pharmacokinetics / Q000652:urine*; D014908:Triticum
D004043:Dietary Fiber; D011620:Psyllium; D012256:Riboflavin