Isolation of a hexaprenylhydroquinone sulfate from the marine sponge Dysidea sp. as an H,K-ATPase inhibitor.
A hexaprenylhydroquinone sulfate has been isolated as an H,K-ATPase inhibitor from a marine sponge Dysidea sp. It also inhibited phospholipase A2 as well as secretion of gastric acid in rats.
Fusetani
N
N
Laboratory of Marine Biochemistry, Faculty of Agriculture, University of Tokyo, Japan.
Sugano
M
M
Matsunaga
S
S
Hashimoto
K
K
Shikama
H
H
Ohta
A
A
Nagano
H
H
D000251:Adenosine Triphosphatases / Q000037:antagonists & inhibitors*; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D005744:Gastric Acid / Q000378:metabolism; D005753:Gastric Mucosa / Q000187:drug effects; D017506:H(+)-K(+)-Exchanging ATPase; D009682:Magnetic Resonance Spectroscopy; D010741:Phospholipases A / Q000037:antagonists & inhibitors; D054467:Phospholipases A2; D011161:Porifera / Q000032:analysis*; D051381:Rats; D013729:Terpenes / Q000302:isolation & purification* / Q000494:pharmacology
D013729:Terpenes; C054388:hexaprenylhydroquinone sulfate; D010741:Phospholipases A; D054467:Phospholipases A2; D000251:Adenosine Triphosphatases; D017506:H(+)-K(+)-Exchanging ATPase