Ulcerative colitis, primary sclerosing cholangitis, bile duct carcinoma, and generalized sarcoidosis. Report of a unique association.
We describe a young man with a hitherto unreported association of chronic ulcerative colitis, primary sclerosing cholangitis (PSC), bile duct carcinoma, and generalized sarcoidosis with features of high-intensity alveolitis. This finding suggests that common immunological mechanisms may be involved in the pathogenesis of these diseases.
Van Steenbergen
W
W
Department of Internal Medicine, University Hospital Gasthuisberg, Leuven, Belgium.
Fevery
J
J
Vandenbrande
P
P
Desmet
V
V
Ponette
E
E
Kerremans
R
R
de Groote
J
J
D002293:Adenocarcinoma, Scirrhous / Q000473:pathology*; D000328:Adult; D001650:Bile Duct Neoplasms / Q000473:pathology*; D001653:Bile Ducts, Intrahepatic / Q000473:pathology; D003093:Colitis, Ulcerative / Q000473:pathology*; D003106:Colon / Q000473:pathology; D006500:Hepatic Duct, Common / Q000473:pathology; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D008103:Liver Cirrhosis / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D012507:Sarcoidosis / Q000473:pathology*