title: Mitochondrial DNA of the yeast Kluyveromyces: guanine-cytosine rich sequence clusters.
abstract: Mitochondrial DNA from the yeast Kluyveromyces marxianus var. lactis (K.lactis) is a circular molecule of 39 kilobase-pairs. A genetic and physical map was constructed. We found that this genome contained a large number of guanine-cytosine (GC)-rich sequence clusters, many of which are characterized by the presence of SacII restriction sites (CCGCGG). The primary sequence of the GC clusters often showed a palindromic structure. These GC clusters were present in several varieties of K.marxianus, but not in others. The presence of these clusters is a major feature that distinguishes K.lactis strains from those of K.marxianus var. marxianus (including K.fragilis).
authors.affiliation: Institut Curie, Section de Biologie, Centre Universitaire, Orsay, France.
authors.forename: A
authors.initials: A
authors.lastname: Ragnini
authors.forename: H
authors.initials: H
authors.lastname: Fukuhara
mesh_terms: D001483:Base Sequence; D003596:Cytosine; D004262:DNA Restriction Enzymes; D004270:DNA, Circular / Q000235:genetics; D004272:DNA, Mitochondrial / Q000235:genetics*; D005800:Genes, Fungal; D006147:Guanine; D007716:Kluyveromyces / Q000235:genetics*; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D004718:Saccharomycetales / Q000235:genetics*
chemical_list: D004270:DNA, Circular; D004272:DNA, Mitochondrial; D006147:Guanine; D003596:Cytosine; D004262:DNA Restriction Enzymes