Liver lesions in hepatitis B viral infection.
A review is made of the various histological lesions observed in hepatitis B virus-related liver diseases, including different forms of acute and chronic hepatitis, cirrhosis, and hepatocellular carcinoma. The elementary lesions discussed include acidophil necrosis (apoptosis), confluent lytic necrosis in its different patterns, piecemeal necrosis, focal necrosis, and dysplastic hepatocytes. Their pathogenesis is explained in the framework of recent developments in the immunopathology of hepatitis B viral infections.
Desmet
V J
VJ
University Hospital St. Rafaël, Department of Medical Research, Catholic University Leuven, Belgium.
D006528:Carcinoma, Hepatocellular / Q000473:pathology; D006509:Hepatitis B / Q000145:classification / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007249:Inflammation / Q000473:pathology; D008099:Liver / Q000473:pathology*; D008103:Liver Cirrhosis / Q000473:pathology; D008113:Liver Neoplasms / Q000473:pathology; D009336:Necrosis