[Preparative isolation of purified antigens of the herpes simplex virus type I and a study of their immunogenic properties].
The HSV-I-containing material prepared in chick embryo fibroblast cultures was concentrated on nuclear filters followed by chromatography on a column with large-pore silica. The MESK detergent was used for isolation of glycoproteins. The glycoprotein preparation was highly immunogenic in experimental animals.
Kliushnik
S Iu
SIu
Berezin
V E
VE
Novitskiĭ
V A
VA
Pushkarskaia
N L
NL
Zaĭdes
V M
VM
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D000954:Antigens, Surface / Q000276:immunology / Q000302:isolation & purification; D000956:Antigens, Viral / Q000276:immunology / Q000302:isolation & purification*; D002642:Chick Embryo; D006023:Glycoproteins / Q000276:immunology / Q000302:isolation & purification; D007114:Immunization; D008722:Methods; D051381:Rats; D018139:Simplexvirus / Q000276:immunology*; D012995:Solubility; D013997:Time Factors; D014776:Virus Cultivation
D000914:Antibodies, Viral; D000954:Antigens, Surface; D000956:Antigens, Viral; D006023:Glycoproteins
Preparativnoe poluchenie ochishchennykh antigenov virusa prostogo gerpesa tipa I i izuchenie ikh immunogennykh svoĭstv.