A direct electron microscopic immunocytochemical study of IgM paraproteinemic neuropathy.
Direct electron microscopic immunohistochemistry of the sural nerve of a patient with neuropathy and an IgMk paraprotein demonstrated that immunoglobulin was deposited throughout the compact myelin. These findings support the notion that immunoglobulin deposition plays a role in the pathogenesis of the neuropathy in vivo.
Mata
M
M
Department of Neurology, Veterans Administration Medical Center, Ann Arbor, MI 48105.
Kahn
S N
SN
Fink
D J
DJ
D000328:Adult; D006801:Humans; D007075:Immunoglobulin M; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D010265:Paraproteinemias / Q000473:pathology*; D010523:Peripheral Nervous System Diseases / Q000473:pathology*; D013497:Sural Nerve / Q000648:ultrastructure
D007075:Immunoglobulin M