[Neuroendocrine disorders observed in the post-critical phase in epileptic patients].
In 10 epileptic patients with generalized seizures, plasma levels of ACTH, prolactin, FSH, LH, TSH, were measured first within 60 minutes after the crisis, then 3 to 5 days later without changes in antiepileptic drugs. Within 1 hour after the seizure, a significant rise of ACTH and prolactin 3 - 4 folds the levels observed in the 2nd measure was present. This was compared to measures made within 1 hour after a syncope in which case it was not present. The post-critic rise of ACTH and prolactin would appear to be a characteristic of generalized epileptic seizures.
Giroud
M
M
Service de Neurologie, CHU Dijon.
Desgres
J
J
Mack
G
G
Dumas
R
R
D000293:Adolescent; D000324:Adrenocorticotropic Hormone / Q000097:blood*; D000328:Adult; D002648:Child; D004827:Epilepsy / Q000097:blood*; D005260:Female; D006065:Gonadotropins, Pituitary / Q000097:blood*; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D013575:Syncope / Q000097:blood*
D006065:Gonadotropins, Pituitary; D000324:Adrenocorticotropic Hormone
Les troubles neuro-endocriniens observés en phase post-critique chez les épileptiques.