[Participation of alpha and beta adrenoreceptors in facilitating and inhibiting the action of the sympathetic nervous system in parasympathetic bradycardia].
Electrical stimulation of the distal vagal cervical end in urethane chloralose anesthetized cats caused bradycardia that could be both enhanced and inhibited during sympathetic activation. Sympathetic activation was induced by electrical stimulation of the sympathetic outflow of the spinal cord at the level of Th 1-Th 3 in pitched cats or by an intravenous injection of tyramine. It has been proved pharmacologically that alpha-adrenoceptors are involved in potentiation. The inhibitory influences are realized via both alpha- and beta-adrenoceptors.
Samonina
G E
GE
Iashina
L P
LP
D000818:Animals; D001919:Bradycardia / Q000503:physiopathology*; D002415:Cats; D004558:Electric Stimulation; D010275:Parasympathetic Nervous System / Q000503:physiopathology*; D010646:Phentolamine / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects / Q000502:physiology*; D011943:Receptors, Adrenergic, beta / Q000187:drug effects / Q000502:physiology*; D013564:Sympathetic Nervous System / Q000187:drug effects / Q000503:physiopathology*; D014326:Tropanes / Q000494:pharmacology; D014439:Tyramine / Q000494:pharmacology
D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D014326:Tropanes; C009599:tropodifene; D011433:Propranolol; D014439:Tyramine; D010646:Phentolamine
Uchastie al'fa- i beta-adrenoretseptorov v realizatsii oblegchaiushchikh i tormoznykh vliianiĭ simpaticheskoĭ nervnoĭ sistemy na parasimpaticheskoe urezhenie serdtsebieniĭ.