title: Karyotypes of 33 patients with clonal aberrations in chronic lymphocytic leukaemia. Review of 216 abnormal karyotypes in chronic lymphocytic leukaemia.
abstract: We report on 33 unpublished patients with clonal anomalies in chronic lymphocytic leukaemia. The literature was thoroughly reviewed in order 1) to quantify the frequency of anomalies found in chronic lymphocytic leukaemia and to give new status to the rarest, 2) to determine whether a given anomaly was an additional anomaly and/or a primary anomaly, and 3) to find out whether strong associations between different anomalies exist in this disease.
authors.affiliation: Département d'Hématologie et Oncologie Médicale, CNRS URA 223, Hôpital Jean-Bernard, Poitiers, France.
authors.forename: J L
authors.initials: JL
authors.lastname: Huret
authors.forename: H
authors.initials: H
authors.lastname: Mossafa
authors.forename: A
authors.initials: A
authors.lastname: Brizard
authors.forename: B
authors.initials: B
authors.lastname: Dreyfus
authors.forename: F
authors.initials: F
authors.lastname: Guilhot
authors.forename: X Q
authors.initials: XQ
authors.lastname: Xue
authors.forename: P
authors.initials: P
authors.lastname: Babin
authors.forename: J
authors.initials: J
authors.lastname: Tanzer
mesh_terms: D002869:Chromosome Aberrations; D002872:Chromosome Deletion; D002999:Clone Cells / Q000648:ultrastructure; D006801:Humans; D007621:Karyotyping; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000235:genetics*; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000648:ultrastructure; D014178:Translocation, Genetic; D014314:Trisomy