title: [Combined antibiotic therapy of acute radiation disease in persons affected during the accident at the Chernobyl nuclear power station].
abstract: One hundred and fifteen patients with acute radiation disease of degrees I to IV affected during the accident at the Chernobyl APS were treated in a specialized hospital. The anti-infection regimen included isolation, air sterilization with ultraviolet light, intravenous administration of broad spectrum of antibiotics (gentamicin, cephalosporins and carbenicillin) and nystatin. Some cases were treated with amphotericin. Some cases were treated with amphotericin B. Out of 22 patients who died at the early periods (days 14 to 34) or at the period of agranulocytosis in 7 patients sepsis was stated. In 5 of them it was complicated by pneumonia. In 5 patients who died at the late periods (days 48 to 99) or at the period of hemopoiesis normalization infectious complications by the death moment were stated: sepsis in 3 patients and pneumonia in 2 patients. The aspect of the microbiological diagnosis and therapy efficacy is discussed.
authors.forename: A E
authors.initials: AE
authors.lastname: Baranov
authors.forename: T V
authors.initials: TV
authors.lastname: Shishkova
authors.forename: T G
authors.initials: TG
authors.lastname: Protasova
authors.forename: T I
authors.initials: TI
authors.lastname: Davydovskaia
mesh_terms: D000059:Accidents; D000900:Anti-Bacterial Agents; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D006801:Humans; D009688:Nuclear Reactors; D011832:Radiation Injuries / Q000188:drug therapy*; D014455:Ukraine
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Kombinirovannaia antibiotikoterapiia ostroĭ luchevoĭ bolezni u postradavshikh pri avarii na Chernobyl'skoĭ AES.