Evaluation of a shell vial centrifugation method for the detection of herpes simplex virus.
A MRC-5 shell vial method was compared to a MRC-5 conventional tube cell culture method in 410 specimens, 88 of which were positive for herpes simplex virus. The shell vial had a sensitivity of 92% and a specificity of 99% when compared to conventional cell culture.
MacDonald
R L
RL
University of California Irvine Medical Center, Department of Pathology, Orange 92668.
Hughes
B L
BL
Aarnaes
S L
SL
Peterson
E M
EM
de la Maza
L M
LM
D002498:Centrifugation / Q000379:methods*; D003588:Cytopathogenic Effect, Viral; D005069:Evaluation Studies as Topic; D018139:Simplexvirus / Q000302:isolation & purification*