Production and characterization of neutralizing monoclonal antibody to a human rotavirus strain with a "super-short" RNA pattern.
A neutralizing monoclonal antibody, B37:1, against a human rotavirus (B37) with a "super-short" RNA pattern was derived. The antibody gave serotype-specific reactions with a panel of standard rotaviruses and was reactive in an enzyme immunoassay. Epidemiological studies of this new human serotype should now be possible.
Tursi
J M
JM
Department of Gastroenterology, Royal Children's Hospital, Parkville, Victoria, Australia.
Albert
M J
MJ
Bishop
R F
RF
D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis / Q000276:immunology*; D000918:Antibody Specificity; D006801:Humans; D007124:Immunoenzyme Techniques; D051379:Mice; D012367:RNA, Viral / Q000032:analysis*; D012401:Rotavirus / Q000145:classification / Q000235:genetics / Q000276:immunology*; D012703:Serotyping; D013045:Species Specificity
D000911:Antibodies, Monoclonal; D012367:RNA, Viral