[Heart rate, blood pressure and systolic time interval in rest and during single-hand exertion in persons exposed to lead and in control subjects].
The hypertonic effect of lead has been known since the beginning of the twentieth century, but now - under better situation of exposure - the lead's effects on the cardiovascular system are controversially discussed. For a direct effect of lead on the heart there are only references in animals. We examined lead exposed workers and control persons using heart rate, blood pressure and systolic time intervals (STI) in rest and during handgrip exercise. In rest we found no differences between exposed and controls. During handgrip exercise there is a sign for left ventricular dysfunction in lead exposed a loss of exercise induced physiological decrease of the preejection period (PEP). Further investigations in large groups - also in follow-up - are necessary for further interpretations.
Reimer
W
W
Tittelbach
U
U
D006225:Hand / Q000502:physiology; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D007854:Lead / Q000633:toxicity*; D009119:Muscle Contraction / Q000187:drug effects; D005082:Physical Exertion; D012146:Rest; D013599:Systole / Q000187:drug effects
D007854:Lead
Verhalten von Herzfrequenz, Blutdruck und systolischen Zeitintervallen in Ruhe und während Einhandarbeit bei Bleiexponierten und Kontrollpersonen.