Cycloadditions in syntheses. XXXVI. 6-Hydroxy-1,2-dihydrocyclobuta [a] naphthalene-2-carboxylic acid: a new synthon for A,B-ring aromatized steroids.
A synthetic method of 6-hydroxy-1,2-dihydrocyclobuta[a]naphthalene-2-carboxylic acid as well as a new methodology for the synthesis of A,B-ring aromatized steroids from its 6-deoxy derivative are elaborated.
Sato
M
M
Pharmaceutical Institute, Tohoku University, Aobayama, Sendai, Japan.
Kawakami
K
K
Suzuki
T
T
Morisawa
H
H
Nishimura
S
S
Kaneko
C
C
D055598:Chemical Phenomena; D002621:Chemistry; D003503:Cyclobutanes / Q000138:chemical synthesis*; D015394:Molecular Structure; D009281:Naphthalenes / Q000138:chemical synthesis*
D003503:Cyclobutanes; D009281:Naphthalenes; C061693:6-hydroxy-1,2-dihydrocyclobuta(a)naphthalene-2-carboxylic acid