Molecular epidemiology of OHIO-1 beta-lactamase.
A total of 31 plasmids, all bearing a gene that encodes a novel, plasmid-mediated Richmond-Sykes class III beta-lactamase designated OHIO-1 and a gene that encodes aminoglycoside 2"-adenyltransferase, have been collected from hospitals in Ohio. By using restriction endonuclease digestion and Southern hybridization, we were able to demonstrate that all these plasmids have a common genetic origin.
Kron
M A
MA
Infectious Diseases Section, Cleveland Veterans Administration Medical Center, Ohio.
Shlaes
D M
DM
Currie-McCumber
C
C
Medeiros
A A
AA
D001419:Bacteria / Q000201:enzymology / Q000235:genetics*; D004262:DNA Restriction Enzymes; D004269:DNA, Bacterial / Q000235:genetics; D009693:Nucleic Acid Hybridization; D010957:Plasmids; D001618:beta-Lactamases / Q000032:analysis*
D004269:DNA, Bacterial; D004262:DNA Restriction Enzymes; D001618:beta-Lactamases