[Effect of autophosphorylation on binding of cyclic adenosine monophosphate by cAMP-dependent protein kinases from the rat brain after x-irradiation].
The results of the studies on the influence of autophosphorylation on cAMP binding by cAMP-dependent protein kinases isolated from cytosol and solubilized synaptic membranes have demonstrated that this chain in the regulation of the enzyme forms under study exhibits early radiosensitivity, the radiation damage to soluble and membrane enzymes being differently pronounced.
Ostapchenko
L I
LI
Vasil'ev
A N
AN
Kucherenko
N E
NE
D000818:Animals; D001921:Brain / Q000201:enzymology / Q000378:metabolism* / Q000528:radiation effects; D000242:Cyclic AMP / Q000378:metabolism*; D003600:Cytosol / Q000201:enzymology / Q000378:metabolism; D005260:Female; D007700:Kinetics; D008297:Male; D010766:Phosphorylation; D011494:Protein Kinases / Q000378:metabolism*; D011833:Radiation Injuries, Experimental / Q000201:enzymology / Q000378:metabolism*; D051381:Rats; D013570:Synaptic Membranes / Q000201:enzymology / Q000378:metabolism
D000242:Cyclic AMP; D011494:Protein Kinases
Vliianie avtofosforilirovaniia na sviazyvanie tsiklicheskogo adenozinmonofosfata tsAMF-zavisimymi proteinkinazami golovnogo mozga krys posle rentgenovskogo oblucheniia.