title: Regulatory functions of cyclic adenosine 3',5'-monophosphate in 1-methyladenine production by starfish follicle cells.
abstract: The biosynthesis of 1-methyladenine (1-MeAde) in follicle cells of the starfish, Asterina pectinifera, occurred in response to a gonad-stimulating substance (GSS). Simultaneously with 1-MeAde production, the intracellular cAMP level immediately increased following the administration of GSS. This level in follicle cells markedly depended on GSS concentration. Although 1-MeAde production was also induced by 1-methyladenosine, it caused no increase in cAMP content. It thus appears that the effect of GSS on starfish follicle cells results in the receptor-mediated formation of cAMP.
authors.forename: M
authors.initials: M
authors.lastname: Mita
authors.forename: N
authors.initials: N
authors.lastname: Ueta
authors.forename: Y
authors.initials: Y
authors.lastname: Nagahama
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives* / Q000502:physiology; D000242:Cyclic AMP / Q000502:physiology*; D005260:Female; D008540:Meiosis; D009866:Oogenesis; D010053:Ovary / Q000502:physiology; D013215:Starfish / Q000502:physiology*
chemical_list: C008407:1-methyladenine; D000242:Cyclic AMP; D000225:Adenine