title: [An autopsy case of Paget's disease of the scrotum with general metastasis].
abstract: An autopsy case of genital Paget's disease with a widespread metastases is reported. A 69-year-old man with redness, itching and swelling of the scrotum obtained dermatological consultation and underwent tumor resection for Paget's disease. At 8 months after discharge, he suffered from a costal fracture because of carcinomatosis of the bone marrow. In laboratory data the serum level of alkaline phosphatase and carcinoembryonic antigen was shown to be high. Four months later, he died of severe congestive edema of the lung with diffuse micrometastases. An autopsy revealed a widespread metastases in various organs and lymph nodes. The Paget cells were positive in carcinoembryonic antigen.
authors.affiliation: 2nd Dept. of Pathology, Ohhara General Hospital.
authors.forename: Y
authors.initials: Y
authors.lastname: Satoh
authors.forename: H
authors.initials: H
authors.lastname: Kanbayashi
authors.forename: A
authors.initials: A
authors.lastname: Azuma
authors.forename: S
authors.initials: S
authors.lastname: Asahina
authors.forename: K
authors.initials: K
authors.lastname: Nakamura
mesh_terms: D000368:Aged; D002272:Carcinoembryonic Antigen / Q000032:analysis; D005834:Genital Neoplasms, Male / Q000473:pathology*; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D009362:Neoplasm Metastasis; D010145:Paget Disease, Extramammary / Q000473:pathology*; D012611:Scrotum
chemical_list: D002272:Carcinoembryonic Antigen