delta-9-Tetrahydrocannabinol analysis in forensic blood specimens using capillary column gas chromatography with nitrogen sensitive detection.
A method for the determination of delta-9-tetrahydrocannabinol (THC) in whole blood that employs hexane extraction followed by identification using gas chromatography with nitrogen/phosphorus detection has been developed. The assay is sensitive to 2 ng THC per mL blood and linear to concentrations up to 120 ng/mL (r = 0.998). Precision is demonstrated by coefficients of variation ranging from 3.6 to 9.1% (within run) and 7.1 to 8.0% (between run).
Ritchie
L K
LK
University of Maryland, Department of Pathology, Baltimore 21201.
Caplan
Y H
YH
Park
J
J
D002849:Chromatography, Gas / Q000379:methods*; D013759:Dronabinol / Q000097:blood*; D005554:Forensic Medicine; D006801:Humans; D009584:Nitrogen / Q000032:analysis; D010758:Phosphorus / Q000032:analysis; D011786:Quality Control
D010758:Phosphorus; D013759:Dronabinol; D009584:Nitrogen