title: Orthotopic liver transplantation for primary sclerosing cholangitis.
abstract: The incidence or diagnostic rate of sclerosing cholangitis is increasing. Because of the lack of effective medical or surgical therapy for patients with end-stage liver disease and sclerosing cholangitis, results with orthotopic liver transplantation were examined. The results of 55 consecutive liver replacements for this disease were reviewed. The 1- and 2-year actuarial survival rates are 71% and 57%, respectively. Orthotopic liver transplantation for end-stage liver disease from sclerosing cholangitis has emerged as the most effective therapy.
authors.affiliation: Department of Surgery, University Health Center of Pittsburgh, University of Pittsburgh, Pennsylvania.
authors.forename: J W
authors.initials: JW
authors.lastname: Marsh
authors.forename: S
authors.initials: S
authors.lastname: Iwatsuki
authors.forename: L
authors.initials: L
authors.lastname: Makowka
authors.forename: C O
authors.initials: CO
authors.lastname: Esquivel
authors.forename: R D
authors.initials: RD
authors.lastname: Gordon
authors.forename: S
authors.initials: S
authors.lastname: Todo
authors.forename: A
authors.initials: A
authors.lastname: Tzakis
authors.forename: C
authors.initials: C
authors.lastname: Miller
authors.forename: D
authors.initials: D
authors.lastname: Van Thiel
authors.forename: T E
authors.initials: TE
authors.lastname: Starzl
mesh_terms: D002759:Adenoma, Bile Duct / Q000601:surgery; D000293:Adolescent; D000328:Adult; D002758:Cholangiography; D002761:Cholangitis / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008113:Liver Neoplasms / Q000601:surgery; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012598:Sclerosis; D013997:Time Factors