title: Paracetamol suppositories: a comparative study.
abstract: Paracetamol suppositories in two different bases were given to children who had fever after operations. Plasma concentrations and the effect on temperature were compared. There was a significant correlation between peak plasma concentrations and maximum drop in temperature. A lipophilic base produced better results than a hydrophilic base.
authors.affiliation: Children's Research Centre, Our Lady's Hospital for Sick Children, Dublin.
authors.forename: S
authors.initials: S
authors.lastname: Cullen
authors.forename: D
authors.initials: D
authors.lastname: Kenny
authors.forename: O C
authors.initials: OC
authors.lastname: Ward
authors.forename: K
authors.initials: K
authors.lastname: Sabra
mesh_terms: D000082:Acetaminophen / Q000008:administration & dosage* / Q000097:blood / Q000627:therapeutic use; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005334:Fever / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D011183:Postoperative Complications / Q000188:drug therapy*; D013488:Suppositories
chemical_list: D013488:Suppositories; D000082:Acetaminophen