"Chronic Epstein-Barr virus infection" syndrome and polymyalgia rheumatica.
Twenty-three patients with polymyalgia rheumatica (PMR) followed in an academic rheumatology practice frequently reported symptoms commonly found in the recently described "chronic fatigue syndrome" or "chronic Epstein-Barr infection syndrome." These symptoms persisted for months after treatment had reduced the severity of the myalgias and lowered the sedimentation rate: periodically disabling fatigue (33%), recurrent pharyngitis (30%), sleep disorder (65%) and arthralgias (70%). However, antibody titers to Epstein-Barr virus in the patients with PMR were not significantly different from those in age and sex matched control subjects.
Buchwald
D
D
Department of Medicine, Brigham and Women's Hospital, Boston 02115.
Sullivan
J L
JL
Leddy
S
S
Komaroff
A L
AL
D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis; D001799:Blood Sedimentation; D002908:Chronic Disease; D005221:Fatigue / Q000150:complications; D006261:Headache / Q000150:complications; D004854:Herpesvirus 4, Human / Q000276:immunology; D006801:Humans; D007244:Infectious Mononucleosis / Q000097:blood / Q000150:complications* / Q000276:immunology / Q000503:physiopathology; D009132:Muscles / Q000503:physiopathology; D010146:Pain; D011111:Polymyalgia Rheumatica / Q000097:blood / Q000150:complications* / Q000276:immunology / Q000503:physiopathology; D013577:Syndrome
D000914:Antibodies, Viral