Effect of hyperthermia on lymphocyte membrane. 2. Spin-labelled non-electrolyte permeability.
The effect of elevated temperatures on the permeability of non-electrolyte spin labels, hydrophilic TEMPOL and more hydrophobic TEMPO across the porcine lymphocyte membrane was investigated. In the range of 41-44 degrees C, temperature-induced changes in the permeation constant were lower for TEMPO than TEMPOL. The data obtained may suggest that the permeability of spin labels across the membrane is sensitive to changes of temperature especially above 43 degrees C.
Koter
M
M
Department of Biophysics, University of Lódź, Banacha, Poland.
Gwoździński
K
K
D000818:Animals; D002463:Cell Membrane Permeability; D002478:Cells, Cultured; D003497:Cyclic N-Oxides / Q000378:metabolism; D004578:Electron Spin Resonance Spectroscopy; D006358:Hot Temperature; D008214:Lymphocytes / Q000378:metabolism*; D013113:Spin Labels; D013552:Swine
D003497:Cyclic N-Oxides; D013113:Spin Labels; C001803:tempol; C003959:TEMPO