Impact of long-term relative bowel rest on conditions for colonic surgery.
Collagen content, bursting wall tension, and suture-holding capacity in the proximal and distal colon of the rat were studied after long-term treatment with a low-residue or a standard laboratory chow diet. Collagen content decreased uniformly in both the proximal and distal colon of the low-residue diet group. In addition, the bursting wall tension of the nonoperated proximal colon was reduced, whereas the breaking strength of a newly constructed anastomosis at three different colonic sites was unaffected.
Udén
P
P
Department of Surgery, Malmö allmänna sjukhus, Lund University, Sweden.
Blomquist
P
P
Jiborn
H
H
Zederfeldt
B
B
D000818:Animals; D001835:Body Weight; D003094:Collagen / Q000032:analysis; D003106:Colon / Q000032:analysis / Q000503:physiopathology*; D003108:Colonic Diseases / Q000601:surgery*; D004043:Dietary Fiber; D006454:Hemoglobins / Q000032:analysis; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012709:Serum Albumin / Q000032:analysis; D013529:Surgical Wound Dehiscence / Q000503:physiopathology*; D013537:Sutures; D013718:Tensile Strength
D004043:Dietary Fiber; D006454:Hemoglobins; D012709:Serum Albumin; D003094:Collagen