title: Predictive value of cranial ultrasound in the newborn baby: a reappraisal.
abstract: During a 36-month period 435 babies of 34 weeks' gestation or less were regularly scanned with ultrasound. A large periventricular/intraventricular haemorrhage developed in 40 babies, and extensive cystic leucomalacia developed in 10. The neurodevelopmental outcome and the frequency of handicap in these 2 groups were compared. 9 of the 18 survivors with a large haemorrhage were found to be completely normal and only 2 showed a major handicap. However, severe cerebral palsy with mental retardation developed in all the survivors with extensive cystic leucomalacia, and 4 of the 7 babies were also cortically blind. These findings suggest that the size of the haemorrhage is not a good predictor of outcome, but that severe cystic leucomalacia is associated with a very poor prognosis.
authors.forename: L S
authors.initials: LS
authors.lastname: de Vries
authors.forename: L M
authors.initials: LM
authors.lastname: Dubowitz
authors.forename: V
authors.initials: V
authors.lastname: Dubowitz
authors.forename: A
authors.initials: A
authors.lastname: Kaiser
authors.forename: S
authors.initials: S
authors.lastname: Lary
authors.forename: M
authors.initials: M
authors.lastname: Silverman
authors.forename: A
authors.initials: A
authors.lastname: Whitelaw
authors.forename: J S
authors.initials: JS
authors.lastname: Wigglesworth
mesh_terms: D001921:Brain / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000175:diagnosis* / Q000473:pathology; D002552:Cerebral Ventricles / Q000473:pathology; D002657:Child Development; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D009460:Neurologic Examination; D011379:Prognosis; D014463:Ultrasonography