Effects of asymmetrical triazine copper complexes on superoxide radical formation and on the Sendai virus multiplication.
The O2- scavenging activity of some ligands of asymmetrical triazine seems to be enhanced when complexed with copper. S1 Cu complex in concentration of 10(-8) M inhibits the multiplication of type 1 (Sendai) parainfluenza virus cultivated on MCA fragments. The possible mechanism of inhibition is discussed.
Zuivertz
A
A
Stefan S. Nicolau Institute of Virology, Bucharest, Romania.
Tomas
S
S
Popescu
A
A
Cristescu
C
C
Tomas
E
E
D000998:Antiviral Agents / Q000494:pharmacology*; D003300:Copper / Q000494:pharmacology*; D010222:Parainfluenza Virus 1, Human / Q000187:drug effects* / Q000502:physiology; D013329:Structure-Activity Relationship; D013481:Superoxides / Q000378:metabolism*; D014227:Triazines / Q000494:pharmacology*; D014779:Virus Replication / Q000187:drug effects*
D000998:Antiviral Agents; D014227:Triazines; D013481:Superoxides; D003300:Copper