Can acid inhibitors be "true" cytoprotective agents?
Cytoprotection is a biological process occurring independently of gastric acid inhibition. Evaluation of the possible cytoprotective activities of antisecretory drugs is therefore difficult, unless appropriate experimental models are employed. The results of cytoprotection studies with gastric acid inhibitors are reported and reviewed herein.
Guslandi
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D000818:Animals; D001241:Aspirin / Q000633:toxicity; D001570:Benzodiazepinones / Q000494:pharmacology; D004195:Disease Models, Animal; D000431:Ethanol / Q000633:toxicity; D005744:Gastric Acid / Q000378:metabolism*; D005753:Gastric Mucosa / Q000187:drug effects* / Q000378:metabolism; D006635:Histamine H2 Antagonists / Q000494:pharmacology; D010890:Pirenzepine
D001570:Benzodiazepinones; D006635:Histamine H2 Antagonists; D010890:Pirenzepine; D000431:Ethanol; D001241:Aspirin