[Malignant myoepithelioma of the breast (histological, immunomorphological and electron microscopic study)].
A rare kind of a breast tumor was identified in a woman of 47. The disease ran a malignant course and presented difficulties for morphological verification. Histological appearance showed areas of spindle-shaped or lamellar cells occasionally encircled with homogeneous hyalin-like substance. Locally, there were structures of alveolar or glandular type with an irregular basal membrane and loose position of cells. The primary histological diagnosis suggested a tumor of mesenchymal origin. Followed by immunomorphologic (monoclonal antibody to KL 1) and electron-microscopic examinations, the diagnosis was verified providing evidence for epithelial nature of the tumor cells, loose, forming glandular-like structures and simulating stromal elements with ultrastructural features typical of myoepithelial differentiation. The evidence obtained justify the tumor definition as a rare neoplasm of the breast known in the literature as myoepithelioma.
Ermilova
V D
VD
Kondakova
T I
TI
Filippova
N A
NA
Gel'shteĭn
V I
VI
Chipysheva
T A
TA
D001943:Breast Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008854:Microscopy, Electron; D008875:Middle Aged; D009208:Myoepithelioma / Q000473:pathology* / Q000648:ultrastructure
Zlokachestvennaia mioépitelioma molochnoĭ zhelezy (gistologicheskoe,immunomorphologicheskoe issledovanie)