Emergence of fluoroquinolone resistance in Bacteroides fragilis accompanied by resistance to beta-lactam antibiotics.
The in vitro susceptibilities of a group of 93 isolates of Bacteroides fragilis collected from 1983 to 1984 to six fluoroquinolones were compared with those of a group of 93 isolates collected from 1986 to 1987. The recently collected strains were less susceptible than the older strains to all of the agents tested. Norfloxacin-resistant (MIC, greater than 100 micrograms/ml) strains were less susceptible to cefoxitin and piperacillin than norfloxacin-susceptible strains.
Kato
N
N
Institute of Anaerobic Bacteriology, Gifu University School of Medicine, Japan.
Miyauchi
M
M
Muto
Y
Y
Watanabe
K
K
Ueno
K
K
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001441:Bacteroides fragilis / Q000187:drug effects*; D004352:Drug Resistance, Microbial; D008826:Microbial Sensitivity Tests; D015363:Quinolones / Q000494:pharmacology*; D047090:beta-Lactams
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D015363:Quinolones; D047090:beta-Lactams