[Selective detection of cytomegalovirus by in situ hybridization].
In two SIDS autopsy cases, in situ hybridization with biotin-labeled DNA probes was used to demonstrate a specific cytomegalovirus (CMV) infection in paraffin-embedded tissue sections. This technique represents a rapid, specific, and highly sensitive tool for the detection of CMV infections and is recommended for routine examination in other suspected viral infections, particularly in cases connected with SIDS.
Cremer
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Abteilung Rechtsmedizin der Medizinischen Fakultät, Rheinisch-Westfälische Technische Hochschule Aachen, Bundesrepublik Deutschland.
D001483:Base Sequence; D003587:Cytomegalovirus / Q000235:genetics*; D003586:Cytomegalovirus Infections / Q000473:pathology*; D015342:DNA Probes; D006801:Humans; D007124:Immunoenzyme Techniques; D007181:Inclusion Bodies, Viral / Q000648:ultrastructure; D007223:Infant; D008297:Male; D009693:Nucleic Acid Hybridization; D010306:Parotid Gland / Q000473:pathology; D013398:Sudden Infant Death / Q000473:pathology*
D015342:DNA Probes
Selektiver Zytomegalievirusnachweis durch "in-situ"-Hybridisierung.