title: Linkage between the loci for mitochondrial malic enzyme (ME2) and coagulation factor XIIIA subunit (F13A).
abstract: The locus for the mitochondrial malic enzyme (ME2) seems to be closely linked to the gene coding for the A subunit of coagulation factor XIII (F13A). From 18 informative families with 54 children a maximum lod score of 4.33 was obtained at a recombination fraction of 0.10. Since the assignment of F13A to the short arm of chromosome 6 was recently confirmed, the locus for ME2 can be added to this linkage group. The map order seems to be: GLO1 - HLA - F13A - ME2.
authors.forename: J
authors.initials: J
authors.lastname: Kömpf
authors.forename: F
authors.initials: F
authors.lastname: Schunter
authors.forename: P
authors.initials: P
authors.lastname: Wernet
authors.forename: H
authors.initials: H
authors.lastname: Ritter
mesh_terms: D000328:Adult; D002648:Child; D002874:Chromosome Mapping; D002906:Chromosomes, Human, 6-12 and X; D005176:Factor XIII / Q000235:genetics*; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D008291:Malate Dehydrogenase / Q000235:genetics*; D008297:Male; D011110:Polymorphism, Genetic; D011995:Recombination, Genetic; D011503:Transglutaminases
chemical_list: D005176:Factor XIII; D008291:Malate Dehydrogenase; D011503:Transglutaminases