title: Use of clonidine in a mixed-drug detoxification regimen: possibility of masking of clinical signs of sedative withdrawal.
abstract: Clonidine hydrochloride masked the signs of sedative withdrawal when it was used in detoxification of a patient with sedative-opiate-amphetamine dependence. Therefore, we urge caution in the use of clonidine in mixed-drug detoxification regimens.
authors.forename: P L
authors.initials: PL
authors.lastname: Hughes
authors.forename: R M
authors.initials: RM
authors.lastname: Morse
mesh_terms: D014151:Anti-Anxiety Agents / Q000009:adverse effects*; D001463:Barbiturates / Q000009:adverse effects*; D001569:Benzodiazepines; D003000:Clonidine / Q000627:therapeutic use*; D003693:Delirium / Q000139:chemically induced; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D013375:Substance Withdrawal Syndrome / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D014151:Anti-Anxiety Agents; D001463:Barbiturates; D001569:Benzodiazepines; D003000:Clonidine