A case of perazine-induced enteritis--allergy or pseudoallergy?
Almost all adverse reactions to neuroleptic drugs in the gastro-intestinal system can be explained by their peripheral cholinergic blocking action with subsequent inhibition of intestinal tone and peristalsis. As a rare condition, severe diarrhoea due to enteritis may occur. A case with this complication is presented, the etiology and pathogenetic factors are discussed.
Meya
U
U
Möller
B
B
Renfordt
E
E
Lobeck
H
H
D000368:Aged; D014150:Antipsychotic Agents / Q000009:adverse effects*; D003866:Depressive Disorder / Q000188:drug therapy*; D003967:Diarrhea / Q000139:chemically induced; D004342:Drug Hypersensitivity / Q000209:etiology*; D004359:Drug Therapy, Combination; D004751:Enteritis / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000187:drug effects; D010464:Perazine / Q000009:adverse effects* / Q000627:therapeutic use
D014150:Antipsychotic Agents; D010464:Perazine