title: [Liver morphology and clinical aspects of a case of cholesterol ester storage disease].
abstract: Liver specimen morphology and clinical course of a case of cholesterol ester storage disease are presented. In a 16-year-old boy on the first biopsy a massive storage of neutral fats was found light microscopically and of cholesterol ester micropolariscopically. Advanced portal field fibrosis and severe reactive hepatitis indicate the danger of progression up to metaplasia. Typical membrane-surrounded lipid inclusions were found electron microscopically in hepatic cells, stellate cells and also in bile duct epithelium.
authors.affiliation: Institut für Pathologie Georg Schmorl, Medizinischen Akademie Carl Gustav Carus, Dresden.
authors.forename: J
authors.initials: J
authors.lastname: Justus
authors.forename: J
authors.initials: J
authors.lastname: Schulze
authors.forename: C
authors.initials: C
authors.lastname: Kemmer
authors.forename: H
authors.initials: H
authors.lastname: Riedel
mesh_terms: D000293:Adolescent; D001707:Biopsy, Needle; D015217:Cholesterol Ester Storage Disease / Q000235:genetics / Q000473:pathology*; D002788:Cholesterol Esters / Q000378:metabolism; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D008099:Liver / Q000473:pathology*; D008111:Liver Function Tests; D008297:Male; D008854:Microscopy, Electron
chemical_list: D002788:Cholesterol Esters
vernacular_title: Lebermorphologie und Klinik eines Falls von Cholesterinester-Speicherkrankheit.