[Determination of serum neuron-specific enolase in bronchial tumors of neuroendocrine origin].
Neurone-specific enolase, a serum marker of neuroendocrine tumours has been determined in small-cell anaplastic bronchial carcinomas, in typical and atypical carcinoid. The marker presents good sensitivity in small-cell tumours and in atypical carcinoids, while blood levels are within normal limits in cases of typical carcinoid. The low serum levels of neurone-specific enolase found in typical carcinoid suggest a failure of the enzyme to express itself in the circulation owing to the poor or lack of cellular necrosis.
Rapellino
M
M
Ospedale Maggiore S. Giovanni Battista, Torino, Servizio di Fisiopatologia Respiratoria e Broncologia.
Pecchio
F
F
Cunazza
M
M
Baldi
S
S
Adamo
M R
MR
Casadio
C
C
Faga
C
C
Baldi
C
C
Oliaro
A
A
Albertino
B
B
D014408:Biomarkers, Tumor / Q000097:blood*; D001984:Bronchial Neoplasms / Q000175:diagnosis*; D003528:Carcinoma, Adenoid Cystic / Q000175:diagnosis*; D002283:Carcinoma, Bronchogenic / Q000175:diagnosis*; D018288:Carcinoma, Small Cell / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis*; D010751:Phosphopyruvate Hydratase / Q000097:blood*; D011863:Radioimmunoassay
D014408:Biomarkers, Tumor; D010751:Phosphopyruvate Hydratase
Determinazione della enolasi neurone specifica sierica nei tumori bronchiali di origine neuroendocrina.