title: The possible role of serotonin in the rhythmicity of the crop of Aplysia dactylomela.
abstract: The isolated perfused crop of Aplysia dactylomela was used to assess the effects of applied serotonin on 1st order small phasic contractions, 2nd order large tonic contractions, and 3rd order slow changes in tonus. Very low concentrations of serotonin may potentiate spontaneous contractions. Concentrations of the order of 10(-7) M serotonin may regularize "beating" of the crop by suppressing large tonic contractions while potentiating phasic contractions. Concentrations higher than 10(-5) M serotonin induce prolonged tonic contracture.
authors.forename: D W
authors.initials: DW
authors.lastname: Wells
authors.forename: R B
authors.initials: RB
authors.lastname: Hill
mesh_terms: D000200:Action Potentials; D000818:Animals; D001048:Aplysia / Q000033:anatomy & histology / Q000502:physiology*; D002395:Catecholamines / Q000494:pharmacology; D002928:Cinanserin / Q000494:pharmacology; D066298:In Vitro Techniques; D009119:Muscle Contraction; D009130:Muscle, Smooth / Q000502:physiology; D010507:Periodicity; D012701:Serotonin / Q000502:physiology*; D014363:Tryptamines / Q000494:pharmacology
chemical_list: D002395:Catecholamines; D014363:Tryptamines; D012701:Serotonin; C030820:tryptamine; D002928:Cinanserin