title: Profound bradycardia after amyl nitrite in patients with a tendency to vasovagal episodes.
abstract: Two patients with mild aortic insufficiency inhaled amyl nitrite during routine echocardiographic examinations. One developed sinus arrest and syncope and the other had pronounced sinus bradycardia. The mechanism of this paradoxical response is unclear. Caution should be exercised when amyl nitrite is administered for diagnostic purposes.
authors.forename: M H
authors.initials: MH
authors.lastname: Rosoff
authors.forename: M V
authors.initials: MV
authors.lastname: Cohen
mesh_terms: D000328:Adult; D000680:Amyl Nitrite / Q000009:adverse effects*; D001022:Aortic Valve Insufficiency / Q000150:complications* / Q000503:physiopathology; D001919:Bradycardia / Q000139:chemically induced* / Q000503:physiopathology; D004452:Echocardiography; D006323:Heart Arrest / Q000139:chemically induced; D006801:Humans; D008297:Male; D013575:Syncope / Q000139:chemically induced
chemical_list: D000680:Amyl Nitrite