Dichlorvos and acetylcholine increase 32P-labelling of phospholipids in cricket central nerve cords.
The susceptibility of central nerve cord phospholipids of Acheta domesticus to stress caused by acetylcholine and the organophosphate insecticide dichlorvos was determined in vitro. Both dichlorvos (10(-5) and 10(-4)M) and acetylcholine (5 X 10(-5)M) stimulated increased labelling of nerve cord phospholipids by 32P. Dichlorvos caused a significant release of radiolabelled material to the medium, while acetylcholine did not.
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D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D004006:Dichlorvos / Q000494:pharmacology*; D006135:Gryllidae / Q000378:metabolism*; D066298:In Vitro Techniques; D009474:Neurons / Q000187:drug effects / Q000378:metabolism*; D009987:Orthoptera / Q000378:metabolism*; D010743:Phospholipids / Q000378:metabolism*; D010761:Phosphorus Radioisotopes
D010743:Phospholipids; D010761:Phosphorus Radioisotopes; D004006:Dichlorvos; D000109:Acetylcholine