Calcium channel blockade: central hemodynamic effects.
Despite differences in vasodilatation, inotropy and chronotropy between verapamil, nifedipine and diltiazem when tested in vitro, these drugs will produce similar central hemodynamic effects in healthy young or middle-aged individuals, provided they are given in equipotent doses. The individual profiles of hemodynamic action of these calcium channel blockers are briefly reviewed and discussed.
Ekelund
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D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000328:Adult; D000818:Animals; D002121:Calcium Channel Blockers / Q000494:pharmacology*; D003326:Coronary Circulation / Q000187:drug effects; D004110:Diltiazem / Q000494:pharmacology; D004347:Drug Interactions; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D009543:Nifedipine / Q000494:pharmacology; D014664:Vasodilation / Q000187:drug effects; D014700:Verapamil / Q000494:pharmacology
D000319:Adrenergic beta-Antagonists; D002121:Calcium Channel Blockers; D014700:Verapamil; D004110:Diltiazem; D009543:Nifedipine