The activity of glutaraldehyde against Clostridium difficile.
The sporicidal activity of 2% glutaraldehyde against Bacillus subtilis var. globigii and Bacillus stearothermophilus was compared with that against Clostridium difficile. The aerobic species, normally chosen for test purposes, survived for 2 h but Cl. difficile was killed in under 10 min. In view of the impractical and lengthy immersions required to satisfy standard tests using non-pathogenic spores, a less stringent standard would probably be more appropriate.
Dyas
A
A
Das
B C
BC
D000447:Aldehydes / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000502:physiology; D003013:Clostridium / Q000502:physiology*; D004202:Disinfectants / Q000494:pharmacology*; D001411:Geobacillus stearothermophilus / Q000502:physiology; D005976:Glutaral / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D013171:Spores, Bacterial / Q000187:drug effects
D000447:Aldehydes; D004202:Disinfectants; D005976:Glutaral