Papillomavirus. Effects upon mother and child.
Papillomaviruses are widespread, sexually transmitted agents with an increasing prevalence. They are associated with a significant risk of genital carcinoma in infected women. Because they can be transmitted to the fetus before or during birth, they are also a risk to the infant born to an infected woman. Laryngeal HPV infections, while presumably much less prevalent than genital tract infections, are associated with a high degree of morbidity and a significant degree of mortality when they cause laryngeal papillomas. Therefore, transmission of these viruses to the fetus is a major problem. Much more information regarding mode of transmission and possible cure for this infection is needed in order to reduce the risk of laryngeal papillomatosis in infants in the future.
Steinberg
B M
BM
Department of Otolaryngology, Long Island Jewish Medical Center, New Hyde Park, New York 11042.
D003218:Condylomata Acuminata / Q000382:microbiology / Q000635:transmission; D005260:Female; D005833:Genital Neoplasms, Female / Q000382:microbiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010212:Papilloma / Q000382:microbiology; D027383:Papillomaviridae; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000635:transmission; D011252:Pregnancy Complications, Neoplastic / Q000382:microbiology; D012142:Respiratory Tract Neoplasms / Q000382:microbiology; D012749:Sexually Transmitted Diseases / Q000635:transmission; D014412:Tumor Virus Infections / Q000635:transmission