title: Neuropeptide Y does not inhibit the release of alpha-MSH from the pars intermedia of the rat adenohypophysis.
abstract: Neuropeptide Y in concentrations from 10(-8) to 10(-6) M inhibits the release of alpha-MSH from the frog (Rana pipiens) pituitary in a reversible, sustained, and concentration-related manner. However, it does not inhibit the release of alpha-MSH from the rat pars intermedia. Thus, while neuropeptide Y may play a role in the control of alpha-MSH release in amphibia, it appears not to be a regulatory peptide for the mammalian pars intermedia.
authors.affiliation: Department of Physiology, University of Western Ontario, London, Canada.
authors.forename: J
authors.initials: J
authors.lastname: Kraicer
authors.forename: B
authors.initials: B
authors.lastname: Lussier
authors.forename: S
authors.initials: S
authors.lastname: Kotanen
authors.forename: B C
authors.initials: BC
authors.lastname: Moor
mesh_terms: D000818:Animals; D066298:In Vitro Techniques; D008297:Male; D009478:Neuropeptide Y / Q000494:pharmacology*; D010903:Pituitary Gland, Anterior / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D011894:Rana pipiens; D051381:Rats; D000521:alpha-MSH / Q000378:metabolism*
chemical_list: D009478:Neuropeptide Y; D000521:alpha-MSH