title: Synthesis of 24-heteroatom-substituted cholestanols.
abstract: Short syntheses of 24-thia-5 alpha,20 xi-cholestan-3 beta-ol, 24-methyl-24-aza-5 alpha,20 xi-cholestan-3 beta-ol, and 24-nor-5 alpha,20 xi-cholan-3 beta-ol from 3 beta-hydroxy-5 alpha-pregnan-20-one are described. The products and synthetic intermediates have been fully characterized by the results of proton NMR, infrared, and high and low resolution mass spectral studies.
authors.affiliation: Department of Chemistry, Princeton University, NJ 08544.
authors.forename: M D
authors.initials: MD
authors.lastname: Rahman
authors.forename: H M
authors.initials: HM
authors.lastname: Seidel
authors.forename: R A
authors.initials: RA
authors.lastname: Pascal
mesh_terms: D002777:Cholestanols / Q000032:analysis / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D011522:Protons
chemical_list: D002777:Cholestanols; D011522:Protons