Disulfiram neuropathy.
A case of sensorimotor polyneuropathy during disulfiram administration is described. This complication partially resolved after the medication was stopped. Pathological observations revealed axonal changes and neurofilament accumulation was found in a few myelinated and unmyelinated axons.
Bergouignan
F X
FX
Département de Neurologie, Université de Bordeaux II, France.
Vital
C
C
Henry
P
P
Eschapasse
P
P
D000437:Alcoholism / Q000188:drug therapy*; D004221:Disulfiram / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009046:Motor Neurons / Q000187:drug effects / Q000648:ultrastructure; D009475:Neurons, Afferent / Q000187:drug effects / Q000648:ultrastructure; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000473:pathology
D004221:Disulfiram