Expression of lectin binding in cutaneous papillomas of animals.
A group of spontaneously occurring animal papillomas which were negative or positive for papillomavirus group-specific antigen were examined with a battery of biotinylated lectins including Con A, WGA, succinylated-WGA, PNA and UEA-I. Canine papillomas, equine papillomas, white-tailed deer fibromas, mule deer fibromas, and bovine fibropapillomas were examined. Each lectin had a specific staining pattern. No obvious differences in staining patterns between normal skin, viral antigen-positive and -negative neoplasms were identified. This may be due to the well-differentiated and organized nature of these tumours.
Whiteley
H E
HE
Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Illinois, Urbana 61801.
Sundberg
J P
JP
D000818:Animals; D000956:Antigens, Viral / Q000276:immunology; D002417:Cattle; D003208:Concanavalin A / Q000378:metabolism; D003670:Deer; D004285:Dogs; D006734:Horse Diseases / Q000378:metabolism*; D006736:Horses; D037102:Lectins / Q000378:metabolism*; D009844:Oligosaccharides / Q000032:analysis / Q000378:metabolism; D010212:Papilloma / Q000378:metabolism / Q000662:veterinary*; D027383:Papillomaviridae / Q000276:immunology; D019887:Peanut Agglutinin; D037121:Plant Lectins; D012878:Skin Neoplasms / Q000378:metabolism / Q000662:veterinary*; D014909:Wheat Germ Agglutinins / Q000378:metabolism
D000956:Antigens, Viral; D037102:Lectins; D009844:Oligosaccharides; D019887:Peanut Agglutinin; D037121:Plant Lectins; C036850:Ulex europaeus lectins; D014909:Wheat Germ Agglutinins; D003208:Concanavalin A