[Enzyme activity of Bacillus polymyxa 153, the producer of polymyxin B, during sporulation and biosynthesis].
Metabolic properties of Bacillus polymyxa 153 were studied during vegetative growth, polymyxin B biosynthesis and active sporulation. In the cell extracts there was detected activity of exoproteases, endoproteases, tricarboxylic acid cycle dehydrogenases and pyruvate dehydrogenase. The enzymes activity in the cells growing into spores was higher than that in the cells of the vegetative developmental type. The activity of the enzymes depended on the culture age.
Ermakova
G N
GN
Filippova
M S
MS
Nefelova
M V
MV
D001407:Bacillus / Q000201:enzymology* / Q000502:physiology; D002952:Citric Acid Cycle; D003470:Culture Media / Q000378:metabolism; D010450:Endopeptidases / Q000378:metabolism; D020689:Exopeptidases; D010447:Peptide Hydrolases / Q000378:metabolism; D011112:Polymyxin B / Q000096:biosynthesis*; D011113:Polymyxins / Q000096:biosynthesis*; D011768:Pyruvate Dehydrogenase Complex / Q000378:metabolism; D013171:Spores, Bacterial / Q000502:physiology; D013997:Time Factors
D003470:Culture Media; D011113:Polymyxins; D011768:Pyruvate Dehydrogenase Complex; D010450:Endopeptidases; D020689:Exopeptidases; D010447:Peptide Hydrolases; D011112:Polymyxin B
Aktivnost' nekotorykh fermentov Bacillus polymyxa 153--produtsenta polimiksina B v protsesse sporoobrazovaniia i biosinteza.