title: Psoriasis and alpha-interferon.
abstract: Two patients with metastatic renal carcinoma who were treated with recombinant-DNA-derived alpha-interferon (rIFN alpha) had exacerbation of concomitant psoriasis, and another patient experienced onset of psoriasis during treatment with rIFN alpha. This suggests that interferons may participate in the pathophysiology of psoriasis.
authors.forename: J R
authors.initials: JR
authors.lastname: Quesada
authors.forename: J U
authors.initials: JU
authors.lastname: Gutterman
mesh_terms: D000208:Acute Disease; D000230:Adenocarcinoma / Q000150:complications / Q000188:drug therapy; D000368:Aged; D006801:Humans; D007370:Interferon Type I / Q000009:adverse effects* / Q000502:physiology / Q000627:therapeutic use; D007680:Kidney Neoplasms / Q000150:complications / Q000188:drug therapy; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000503:physiopathology*
chemical_list: D007370:Interferon Type I