[The state of membrane structures of heart cells during ischemia].
Under conditions of perfusion of isolated rabbit heart in aerobic medium and, especially, during ischemia, cytochrome c was liberated from heart cells into perfusate, thus indicating that integrity of mitochondrial outer membrane and of cell membrane was impaired. In situ developed deficiency of cytochrome c was distinctly less as compared with isolated mitochondria (50%, 3 hrs perfusion in ischemia), which appears to occur in response to ultrastructural impairments of mitochondria arising during their isolation and to other reasons.
Dagis
A I
AI
Toleĭkis
A I
AI
Prashkiavichius
A K
AK
D000818:Animals; D003327:Coronary Disease / Q000201:enzymology / Q000378:metabolism*; D003574:Cytochrome c Group / Q000378:metabolism; D007425:Intracellular Membranes / Q000201:enzymology / Q000378:metabolism*; D008929:Mitochondria, Heart / Q000201:enzymology / Q000378:metabolism*; D009211:Myoglobin / Q000378:metabolism; D010084:Oxidation-Reduction; D011817:Rabbits
D003574:Cytochrome c Group; D009211:Myoglobin
Izuchenie tselostnosti membrannykh struktur kletok serdtsa pri ishemii.