title: Plasmatic beta-endorphin levels and thalamic surgery for pain.
abstract: Plasma beta-endorphin levels were found to be significantly lower in patients suffering from chronic pain of malignant etiology than in a control group. After a bilateral stereotactic cryothalamotomy in Centrum Medianum and Parafascicularis nuclei, a good clinical result and a significant increase in plasma beta-endorphin levels were obtained.
authors.forename: J A
authors.initials: JA
authors.lastname: Lopez
authors.forename: F
authors.initials: F
authors.lastname: Perán
authors.forename: A
authors.initials: A
authors.lastname: Altuzarra
authors.forename: F
authors.initials: F
authors.lastname: Garrido
authors.forename: V
authors.initials: V
authors.lastname: Arjona
mesh_terms: D000328:Adult; D000368:Aged; D003452:Cryosurgery; D004723:Endorphins / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000097:blood / Q000628:therapy*; D010148:Intractable Pain / Q000097:blood / Q000628:therapy*; D013238:Stereotaxic Techniques; D013787:Thalamic Nuclei / Q000601:surgery*; D001615:beta-Endorphin
chemical_list: D004723:Endorphins; D001615:beta-Endorphin