Effect of dopaminergic drugs on striatal acetylcholine concentration.
Striatal acetylcholine concentration was determined after administration of varying doses of apomorphine, (+)-PPP and (-)-PPP to rats. (+)-PPP at 3 and 10 mg kg-1 is a dopamine agonist, whereas (-)-PPP at 0.3 and 3 mg kg-1 is a dopamine antagonist in the striatum.
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D000109:Acetylcholine / Q000032:analysis*; D000818:Animals; D001058:Apomorphine / Q000494:pharmacology*; D003342:Corpus Striatum / Q000032:analysis / Q000187:drug effects*; D008297:Male; D010880:Piperidines / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D011954:Receptors, Dopamine / Q000187:drug effects*
D010880:Piperidines; D011954:Receptors, Dopamine; C026539:preclamol; D001058:Apomorphine; D000109:Acetylcholine