title: Hyperthermia improves local tumour control in locally advanced breast cancer.
abstract: We report three patients with advanced breast cancer who received hyperthermia (43 degrees C over 1 h, weekly x 4) and radiotherapy as palliative treatment for chest-wall recurrence. The case reports demonstrate situations where hyperthermia may be beneficial. These include tumours where radiotherapy alone is not expected to achieve control, such as large fungating tumours, and in previously irradiated areas. In these patients, hyperthermia with radiation achieves better local control of the tumour and delays the need for systemic chemotherapy. This may improve the quality of palliation.
authors.affiliation: Department of Oncology, Haukeland Hospital, University of Bergen, Norway.
authors.forename: G
authors.initials: G
authors.lastname: Wiedemann
authors.forename: O
authors.initials: O
authors.lastname: Mella
authors.forename: R S
authors.initials: RS
authors.lastname: Coltart
authors.forename: B C
authors.initials: BC
authors.lastname: Schem
authors.forename: O
authors.initials: O
authors.lastname: Dahl
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000628:therapy*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000628:therapy*