[Effect of neuroleptics on the thermoregulatory mechanisms in normo- and hypothermia].
The time of occurrence of three stages of hypothermia (mild, moderate and deep with the rectal temperature of 33, 26 and 19 degrees C, respectively) was recorded in acute experiments on rats cooled in water (7 degrees C). It was established that under normothermia aminazine exerted the hypothermic effect and rausedil (24 hrs) the hyperthermic effect. At external cooling both aminazine and rausedil (4 hrs) exhibit the antihypothermic action.
Bazhanov
N O
NO
Saliaev
V N
VN
D000818:Animals; D014150:Antipsychotic Agents / Q000494:pharmacology*; D001831:Body Temperature / Q000187:drug effects*; D001833:Body Temperature Regulation / Q000187:drug effects*; D002746:Chlorpromazine / Q000494:pharmacology; D004329:Droperidol / Q000494:pharmacology; D006220:Haloperidol / Q000494:pharmacology; D007035:Hypothermia / Q000503:physiopathology*; D007036:Hypothermia, Induced / Q000379:methods; D008297:Male; D051381:Rats; D012110:Reserpine / Q000494:pharmacology; D013821:Thermometers; D013997:Time Factors
D014150:Antipsychotic Agents; D012110:Reserpine; D006220:Haloperidol; D004329:Droperidol; D002746:Chlorpromazine
Vliianie neĭroleptikov na termoreguliatornye mekhanizmy pri normo- i gipotermii.