title: [Comparison of indomethacin and ketobemidone as analgesics in acute cholecystitis].
abstract: In an open, randomized prospective clinical trial the analgesic effect of indomethacin and ketobemidon was compared in 67 patients with acute cholecystitis (28 received 5 mg ketobemidon and 39 received 50 mg indomethacin). Both drugs showed a good and significant pain relief, exhibiting no significant difference in the analgesic effect and no serious adverse reactions. It was concluded that indomethacin administered intravenously is an alternative to ketobemidon intravenously in the treatment of pain resulting from acute cholecystitis and may offer some advantages.
authors.forename: T
authors.initials: T
authors.lastname: Mätzsch
authors.forename: D
authors.initials: D
authors.lastname: Holmlund
mesh_terms: D000208:Acute Disease; D000701:Analgesics, Opioid / Q000627:therapeutic use*; D002763:Cholecystectomy; D002764:Cholecystitis / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use*; D008297:Male; D008614:Meperidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008875:Middle Aged; D010276:Parasympatholytics / Q000627:therapeutic use
chemical_list: D000701:Analgesics, Opioid; D010276:Parasympatholytics; D008614:Meperidine; C012394:ketobemidone; D007213:Indomethacin
vernacular_title: Vergleich von Indometacin und Ketobemidon als Analgetikum bei akuter Cholecystitis.