Different effects of three kinds of somatostatin (15-28, 1-14, 1-28) on rabbit's platelet aggregation.
We studied the different effects of three kinds of somatostatin (somatostatin 1-14, somatostatin 15-28, somatostatin 1-28) on the aggregation of rabbit's platelets. It was clarified that somatostatin 15-28 had inhibitory effects on rabbit's platelet aggregation stronger than somatostatin 1-14 did, and that somatostatin 1-28 did not have any such effects. These anti-aggregatory effects of somatostatin were stronger when induced by collagen than induced by ADP.
Fuse
I
I
Ito
S
S
Takagi
A
A
Shibata
A
A
D000244:Adenosine Diphosphate / Q000494:pharmacology; D000818:Animals; D003094:Collagen / Q000494:pharmacology; D010974:Platelet Aggregation / Q000187:drug effects*; D011817:Rabbits; D013004:Somatostatin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D053561:Somatostatin-28
C016385:dihydrosomatostatin; D013004:Somatostatin; D000244:Adenosine Diphosphate; D053561:Somatostatin-28; D003094:Collagen