title: Thy-1: a hydrophobic transmembrane segment at the carboxyl terminus.
abstract: Thy-1 is a membrane glycoprotein distributed throughout mammalian species and expressed on brain tissue and various cells of the hematopoietic lineage. The nucleotide sequences of rat and mouse Thy-1 genes revealed a similar gene organization and the existence of an extra 31 amino acid segment at the carboxyl terminus not described previously. These extra amino acids, highly conserved in both species, include a 20 amino acid hydrophobic segment at the carboxyl terminus, which may be responsible for integration of Thy-1 within the plasma membrane.
authors.forename: T
authors.initials: T
authors.lastname: Seki
authors.forename: H C
authors.initials: HC
authors.lastname: Chang
authors.forename: T
authors.initials: T
authors.lastname: Moriuchi
authors.forename: R
authors.initials: R
authors.lastname: Denome
authors.forename: J
authors.initials: J
authors.lastname: Silver
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000954:Antigens, Surface / Q000096:biosynthesis / Q000235:genetics; D001483:Base Sequence; D002462:Cell Membrane / Q000378:metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D003001:Cloning, Molecular; D004247:DNA; D005796:Genes; D051379:Mice; D051381:Rats; D018800:Thy-1 Antigens
chemical_list: D000954:Antigens, Surface; D018800:Thy-1 Antigens; D004247:DNA