[Obtaining monoclonal antibodies to Bordetella pertussis antigens].
The immunization of mice with the protein fraction of B. pertussis strain 305 has made it possible to obtain hybridomas producing monoclonal antibodies to B. pertussis antigens. Ascitic fluids containing monoclonal antibodies react in the ELISA in high titers and actively agglutinate B. pertussis strains 305 and 475.
Sviridov
V V
VV
Kozhevnikova
E V
EV
D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis*; D000911:Antibodies, Monoclonal / Q000096:biosynthesis*; D000942:Antigens, Bacterial / Q000276:immunology*; D001202:Ascitic Fluid / Q000473:pathology; D001426:Bacterial Proteins / Q000276:immunology; D001886:Bordetella pertussis / Q000276:immunology*; D002460:Cell Line; D005260:Female; D005620:Freund's Adjuvant; D006824:Hybridization, Genetic; D007114:Immunization / Q000379:methods; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009101:Multiple Myeloma / Q000473:pathology; D010567:Pertussis Vaccine / Q000276:immunology; D013154:Spleen
D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D010567:Pertussis Vaccine; D005620:Freund's Adjuvant
Poluchenie monoklonal'nykh antitel k antigenam Bordetella pertussis.