title: Imaging neural crest tumours with 123I-metaiodobenzylguanidine and X-ray computed tomography: a comparative study.
abstract: Iodine-123 metaiodobenzylguanidine (MIBG) has been used as a diagnostic agent for imaging neural crest tumours. In a retrospective study of 27 patients, the role of 123I MIBG scintigraphy and X-ray computed tomography (CT) for detection of disease was compared. Both imaging techniques were accurate in the identification of these tumours. Iodine-123 MIBG was slightly more accurate in detecting metastatic disease. Computed tomography of tumours was useful in planning appropriate metastatic intervention. We suggest 123I MIBG should be the primary imaging procedure followed by CT in the investigation of these patients.
authors.affiliation: Department of Nuclear Medicine, St Bartholomew's Hospital, London.
authors.forename: J
authors.initials: J
authors.lastname: Bomanji
authors.forename: B G
authors.initials: BG
authors.lastname: Conry
authors.forename: K E
authors.initials: KE
authors.lastname: Britton
authors.forename: R H
authors.initials: RH
authors.lastname: Reznek
mesh_terms: D019797:3-Iodobenzylguanidine; D000328:Adult; D005729:Ganglioneuroma / Q000000981:diagnostic imaging; D006801:Humans; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D009380:Neoplasms, Nerve Tissue / Q000000981:diagnostic imaging*; D009447:Neuroblastoma / Q000000981:diagnostic imaging; D010235:Paraganglioma / Q000000981:diagnostic imaging; D010673:Pheochromocytoma / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
chemical_list: D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D019797:3-Iodobenzylguanidine