title: Release of pancreatic secretory trypsin inhibitor from human hepatoblastoma cells on stimulation with cytokines.
abstract: To determine whether or not human pancreatic secretory trypsin inhibitor (PSTI) is an acute phase reactant released from hepatocytes, we investigated the effects of various cytokines on the release of PSTI from cultured human hepatoblastoma cells. PSTI was synthesized in human hepatoblastoma cells and released on stimulation with various cytokines: interleukin-1, tumor necrosis factor and interferon-beta.
authors.affiliation: Second Department of Surgery, Osaka University Medical School, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Murata
authors.forename: M
authors.initials: M
authors.lastname: Ogawa
authors.forename: K
authors.initials: K
authors.lastname: Uda
authors.forename: N
authors.initials: N
authors.lastname: Matsuura
authors.forename: Y
authors.initials: Y
authors.lastname: Watanabe
authors.forename: T
authors.initials: T
authors.lastname: Baba
authors.forename: T
authors.initials: T
authors.lastname: Mori
mesh_terms: D001685:Biological Factors / Q000494:pharmacology*; D006528:Carcinoma, Hepatocellular / Q000378:metabolism*; D016207:Cytokines; D006801:Humans; D007370:Interferon Type I / Q000494:pharmacology; D007375:Interleukin-1 / Q000494:pharmacology; D008113:Liver Neoplasms; D010179:Pancreas / Q000201:enzymology; D011994:Recombinant Proteins; D014361:Trypsin Inhibitors / Q000378:metabolism*; D014407:Tumor Cells, Cultured; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology
chemical_list: D001685:Biological Factors; D016207:Cytokines; D007370:Interferon Type I; D007375:Interleukin-1; D011994:Recombinant Proteins; D014361:Trypsin Inhibitors; D014409:Tumor Necrosis Factor-alpha