The zoapatle. XI. Effects elicited by Montanoa tomentosa and Montanoa frutescens on rat uterine strips.
Zoapatle aqueous crude extract (ZACE) obtained from Montanoa tomentosa (M.t.) inhibits the in vitro spontaneous contractility pattern of rat uterine tissue. The opposite effect was observed with ZACE from Montanoa frutescens (M.f.) in the same preparation. Both plant extracts, M.t. and M.f., increased the in vitro spontaneous contractility pattern in the uterine guinea pig assay. In depolarized uterine tissue, propranolol (beta-blocker) inhibited the relaxing effect induced by M.t.. Atropine (cholinergic antagonist) abolished the increase in uterus contractility produced by the presence of M.f.
Perusquía
M
M
Sánchez
E
E
Ponce-Monter
H
H
Estrada
A V
AV
Pedrón
N
N
Valencia
A
A
Guzmán
A
A
Gallegos
A J
AJ
D000109:Acetylcholine / Q000494:pharmacology; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D002369:Castration; D004971:Estrus; D005260:Female; D035924:Montanoa; D009126:Muscle Relaxation / Q000187:drug effects; D009638:Norepinephrine / Q000494:pharmacology; D010082:Oxepins / Q000302:isolation & purification / Q000494:pharmacology*; D010276:Parasympatholytics / Q000494:pharmacology; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000032:analysis*; D011188:Potassium / Q000494:pharmacology; D011247:Pregnancy; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D013045:Species Specificity; D014590:Uterine Contraction / Q000187:drug effects*
D000319:Adrenergic beta-Antagonists; D010082:Oxepins; D010276:Parasympatholytics; D010936:Plant Extracts; D001285:Atropine; D011433:Propranolol; D000109:Acetylcholine; D011188:Potassium; D009638:Norepinephrine