[Response of the secretory glands of the stomach to peptide injection into the hypothalamus, caudate nucleus and amygdala].
In chronic experiments on dogs, microapplication of neurotensin into the hypothalamus or amygdala combined with histamin or pentagastrin stimulation of the stomach secretory function significantly reduced the stomach secretion. Microapplication of somatostatin into the hypothalamus or amygdala combined with i.v. administration of pentagastrin increased two-fold the stomach secretion. The same increasing effect occurred after microapplication of methionin or leucin-5-enkephalin retroanalogue into the hypothalamus or amygdala.
Barashkova
G M
GM
Iakimovskiĭ
A F
AF
Smirnova
A P
AP
Shvachkin
Iu P
IuP
Zavalishina
N A
NA
D000679:Amygdala / Q000187:drug effects*; D000818:Animals; D001931:Brain Mapping; D002421:Caudate Nucleus / Q000187:drug effects*; D004285:Dogs; D004745:Enkephalins / Q000494:pharmacology; D005744:Gastric Acid / Q000378:metabolism; D005750:Gastric Juice / Q000378:metabolism; D005753:Gastric Mucosa / Q000378:metabolism*; D007031:Hypothalamus / Q000187:drug effects*; D009496:Neurotensin / Q000494:pharmacology; D010455:Peptides / Q000494:pharmacology*; D013004:Somatostatin / Q000494:pharmacology
D004745:Enkephalins; D010455:Peptides; D009496:Neurotensin; D013004:Somatostatin
Otvet sekretornykh zhelez zheludochka na vvedenie peptidov v gipotalamus, khvostatoe iadro i mindalinu.