title: Controlled trial of oligoantigenic treatment in the hyperkinetic syndrome.
abstract: 76 selected overactive children were treated with an oligoantigenic diet, 62 improved, and a normal range of behaviour was achieved in 21 of these. Other symptoms, such as headaches, abdominal pain, and fits, also often improved. 28 of the children who improved completed a double-blind, crossover, placebo-controlled trial in which foods thought to provoke symptoms were reintroduced. Symptoms returned or were exacerbated much more often when patients were on active material than on placebo. 48 foods were incriminated. Artificial colorants and preservatives were the commonest provoking substances, but no child was sensitive to these alone.
authors.forename: J
authors.initials: J
authors.lastname: Egger
authors.forename: C M
authors.initials: CM
authors.lastname: Carter
authors.forename: P J
authors.initials: PJ
authors.lastname: Graham
authors.forename: D
authors.initials: D
authors.lastname: Gumley
authors.forename: J F
authors.initials: JF
authors.lastname: Soothill
mesh_terms: D000293:Adolescent; D001289:Attention Deficit Disorder with Hyperactivity / Q000178:diet therapy* / Q000209:etiology / Q000523:psychology; D002648:Child; D002652:Child Behavior; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D005505:Food Coloring Agents / Q000009:adverse effects; D005512:Food Hypersensitivity / Q000150:complications*; D005520:Food Preservatives / Q000009:adverse effects; D006801:Humans; D008297:Male; D011581:Psychological Tests
chemical_list: D005505:Food Coloring Agents; D005520:Food Preservatives