Vasopressin reduces blood loss from second-trimester dilatation and evacuation abortion.
In a double-blind randomised trial, the effect of paracervical injection of vasopressin was compared with placebo on blood loss from dilatation and evacuation abortion. Vasopressin reduced blood loss significantly, an effect that became clinically more important with advancing gestational age. Blood pressure was unchanged.
Schulz
K F
KF
Grimes
D A
DA
Christensen
D D
DD
D000028:Abortion, Induced / Q000009:adverse effects* / Q000379:methods; D000293:Adolescent; D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D004107:Dilatation and Curettage / Q000009:adverse effects*; D005260:Female; D005865:Gestational Age; D006470:Hemorrhage / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D007431:Intraoperative Complications; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011897:Random Allocation; D014667:Vasopressins / Q000627:therapeutic use*
D014667:Vasopressins