title: Eosinophilic cellulitis associated with urticaria. A report of two cases.
abstract: Two patients with the clinical and histopathologic findings of eosinophilic cellulitis are presented. In one patient there was a definite relationship between upper respiratory tract infection and flare-ups of eosinophilic cellulitis. This patient's condition was superimposed on a long history of chronic urticaria. In the other patient a relationship to recurrent sinusitis was possible but not definite. There were no other contributory underlying skin diseases in either patient. Eosinophilic cellulitis is not likely a disease entity as such but, instead, represents a severe urticarial hypersensitivity reaction to various stimuli. Collagen alteration by eosinophil granules results in flame figure formation and a granulomatous response, which may explain the prolonged persistence of the lesions.
authors.forename: J W
authors.initials: JW
authors.lastname: Dijkstra
authors.forename: W F
authors.initials: WF
authors.lastname: Bergfeld
authors.forename: W D
authors.initials: WD
authors.lastname: Steck
authors.forename: R J
authors.initials: RJ
authors.lastname: Tuthill
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D002481:Cellulitis / Q000150:complications* / Q000473:pathology; D004802:Eosinophilia / Q000150:complications / Q000473:pathology; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D008297:Male; D012852:Sinusitis / Q000150:complications / Q000188:drug therapy; D012867:Skin / Q000473:pathology; D014581:Urticaria / Q000150:complications*
chemical_list: D006634:Histamine H1 Antagonists