title: [Cytochemical studies of T- and B-lymphocyte subpopulations in normal conditions and in malignant lymphoproliferative diseases].
abstract: Data from literature and results of the authors' own investigations concerning cytochemical peculiarities of T- and B-lymphocyte subpopulations at the antigen-independent and antigen-dependent differentiation stages are reviewed. Enzyme-cytochemical characteristics for human lymphoid cells at early ontogenesis are presented, peculiarities of cells are given in the thymus-dependent and thymus-independent sites of lymphopoiesis organs and certain types of patch-forming cells are discussed. Data on the enzyme topography in the functionally different subpopulations of lymphocytes identified by a set of the monoclonal antibodies are elucidated. It is shown that the combined application of immunological and cytochemical methods permits establishing more precisely the cell origin and maturity level for different forms and variants of tumour diseases of the lymphoid tissue.
authors.forename: D F
authors.initials: DF
authors.lastname: Gluzman
authors.forename: S P
authors.initials: SP
authors.lastname: Sidorenko
authors.forename: V A
authors.initials: VA
authors.lastname: Nadgornaia
authors.forename: L M
authors.initials: LM
authors.lastname: Skliarenko
mesh_terms: D015720:5'-Nucleotidase; D000135:Acid Phosphatase / Q000378:metabolism; D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D001402:B-Lymphocytes / Q000145:classification* / Q000201:enzymology; D002265:Carboxylic Ester Hydrolases / Q000378:metabolism; D018819:Dipeptidyl Peptidase 4; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases / Q000378:metabolism; D005966:Glucuronidase / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D007938:Leukemia / Q000276:immunology*; D008223:Lymphoma / Q000276:immunology*; D051379:Mice; D009708:Nucleotidases / Q000378:metabolism; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000145:classification* / Q000201:enzymology
chemical_list: D000911:Antibodies, Monoclonal; D002265:Carboxylic Ester Hydrolases; C021855:naphthylbutyrate esterase; D009708:Nucleotidases; D000135:Acid Phosphatase; D015720:5'-Nucleotidase; D005966:Glucuronidase; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; D018819:Dipeptidyl Peptidase 4; D000251:Adenosine Triphosphatases
vernacular_title: Tsitokhimicheskie issledovaniia subpopuliatsiĭ T- i B-limfotsitov v norme i pri zlokachestvennykh limfoproliferativnykh zabolevaniiakh.