Ontogeny of neurotensin receptor binding sites in the rat visual cortex.
The ontogeny of neurotensin receptor binding sites in the rat visual cortex was examined by in situ receptor autoradiography. Binding sites were present in the embryonic cortex and showed extremely high densities at birth and in early postnatal life. Their densities began a gradual decline in the second postnatal week to reach very low levels in adult animals. These results suggest that neurotensin receptor binding sites may play a role in cortical development.
Lobo
D H
DH
Department of Anatomy and Developmental Biology, University College London, U.K.
Parnavelas
J G
JG
D000818:Animals; D051381:Rats; D011919:Rats, Inbred Strains; D018028:Receptors, Neurotensin; D017981:Receptors, Neurotransmitter / Q000378:metabolism*; D014793:Visual Cortex / Q000196:embryology* / Q000254:growth & development / Q000378:metabolism
D018028:Receptors, Neurotensin; D017981:Receptors, Neurotransmitter