title: [Comparative study between alkaline phosphatase and gamma-glutamyltranspeptidase in the diagnosis of hepatic metastases].
abstract: Diagnostic values of alkaline phosphatases (AP) and gamma-glutamyl-transpeptidase (GGT) in hepatic metastases were compared in 48 patients with digestive carcinomas. The study was a prospective one conducted under blind conditions. The AP was less sensitive (0.50) than the GGT (0.86) but was more specific (0.96 as against 0.88). Diagnostic value of GGT (0.87) was therefore greater than of AP (0.75). Positive predictive value of AP was 0.70 and of GGT 0.57. The risk of detecting hepatic metastases was 9% if the AP was normal and 2% if the GGT was normal.
authors.forename: E
authors.initials: E
authors.lastname: Osanaga
authors.forename: A
authors.initials: A
authors.lastname: Larre Borges
authors.forename: J
authors.initials: J
authors.lastname: Sanguinetti
authors.forename: G
authors.initials: G
authors.lastname: Mancusso
authors.forename: A
authors.initials: A
authors.lastname: Lopez
authors.forename: U
authors.initials: U
authors.lastname: Larreborges
mesh_terms: D000328:Adult; D000368:Aged; D000469:Alkaline Phosphatase / Q000097:blood*; D004796:Clinical Enzyme Tests; D003937:Diagnosis, Differential; D004938:Esophageal Neoplasms / Q000473:pathology; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D005723:gamma-Glutamyltransferase / Q000097:blood*
chemical_list: D005723:gamma-Glutamyltransferase; D000469:Alkaline Phosphatase
vernacular_title: Etude comparative entre la phosphatase alcaline et la gamma-glutamyl-transpeptidase dans le diagnostic des métastases hépatiques.