title: Omega-amidase pathway in the degradation of glutamine in Neurospora crassa.
abstract: Evidence for the participation of the glutamine transaminase-omega-amidase pathway in the utilization of glutamine in Neurospora crassa was obtained. Its participation is indicated by the in vitro activities of glutamine transaminase and omega-amidase, the in vivo accumulation of alpha-ketoglutaramate when an inhibitor of transamidases is present, and the inhibition by aminooxyacetic acid and 6-diazo-5-oxo-L-norleucine of the ammonium excreted in the presence of glutamine by a mutant strain that lacks glutamate dehydrogenase and glutamate synthase.
authors.forename: J
authors.initials: J
authors.lastname: Calderón
authors.forename: E
authors.initials: E
authors.lastname: Morett
authors.forename: J
authors.initials: J
authors.lastname: Mora
mesh_terms: D000581:Amidohydrolases / Q000032:analysis*; D005974:Glutamate-Ammonia Ligase / Q000032:analysis; D005973:Glutamine / Q000378:metabolism*; D009491:Neurospora / Q000378:metabolism*; D009492:Neurospora crassa / Q000378:metabolism*; D000637:Transaminases / Q000032:analysis*
chemical_list: D005973:Glutamine; D000637:Transaminases; C020656:glutamine-pyruvate aminotransferase; D000581:Amidohydrolases; D005974:Glutamate-Ammonia Ligase