title: Structure of the murine Thy-1 gene.
abstract: We have cloned the murine Thy-1.1 (AKR) and Thy-1.2 (Balb/c) genes. The complete exon/intron structure and the nucleotide sequence of the Thy-1.2 gene was determined. The gene contains four exons and three intervening sequences. The complete transcriptional unit gives rise to a tissue and developmental stage-specific mRNA of 1850 bp. The 5' end of the gene has multiple initiation sites and a non-TATA box promoter. The 3' end shows a single polyadenylation site after a very long untranslated region.
authors.forename: V
authors.initials: V
authors.lastname: Giguére
authors.forename: K
authors.initials: K
authors.lastname: Isobe
authors.forename: F
authors.initials: F
authors.lastname: Grosveld
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000954:Antigens, Surface / Q000235:genetics*; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000032:analysis*; D004262:DNA Restriction Enzymes; D005796:Genes; D006367:HeLa Cells; D006801:Humans; D051379:Mice; D008815:Mice, Inbred Strains; D010957:Plasmids; D012333:RNA, Messenger / Q000235:genetics; D051381:Rats; D013045:Species Specificity; D018800:Thy-1 Antigens; D014158:Transcription, Genetic; D014162:Transfection
chemical_list: D000954:Antigens, Surface; D012333:RNA, Messenger; D018800:Thy-1 Antigens; D004247:DNA; D004262:DNA Restriction Enzymes