title: [Familial cancer. Initial results of an inquiry into its occurrence in Basel].
abstract: The initial results of a systematic study conducted in Basel on the existence of relatives with cancer in the families of more than 600 tumour patients indicate that neoplasm of all organs have forms in whose etiology genetic predisposition is an important factor. This is illustrated by the examples of mammary carcinoma, colorectal carcinoma, gastric carcinoma and lymphoproliferative diseases. Research into genetic predisposition to cancer is of practical value in order to protect persons at risk from the serious consequences of malignant tumors, and also of scientific interest because the characterisation of certain tumours can provide a fundamental insight into the pathogenesis of these diseases.
authors.forename: H
authors.initials: H
authors.lastname: Müller
authors.forename: N
authors.initials: N
authors.lastname: Bürki
authors.forename: A
authors.initials: A
authors.lastname: Gencik
authors.forename: A
authors.initials: A
authors.lastname: Gencikova
authors.forename: E
authors.initials: E
authors.lastname: Kovacs
authors.forename: M
authors.initials: M
authors.lastname: Roth
authors.forename: N
authors.initials: N
authors.lastname: Trächslin
authors.forename: B
authors.initials: B
authors.lastname: Voegtli
authors.forename: W
authors.initials: W
authors.lastname: Weber
mesh_terms: D001943:Breast Neoplasms / Q000235:genetics; D002869:Chromosome Aberrations; D003110:Colonic Neoplasms / Q000235:genetics; D004260:DNA Repair; D005260:Female; D006689:Hodgkin Disease / Q000235:genetics; D006801:Humans; D008297:Male; D009377:Multiple Endocrine Neoplasia / Q000235:genetics; D009369:Neoplasms / Q000453:epidemiology / Q000235:genetics*; D009378:Neoplasms, Multiple Primary / Q000235:genetics; D010375:Pedigree; D013274:Stomach Neoplasms / Q000235:genetics; D013557:Switzerland
vernacular_title: Familiäre Tumorkrankheiten. Erste Ergebnisse einer Erhebung über ihr Vorkommen in Basel.