The 65 K DNA binding protein appears early in HSV-1 replication.
During the infection cycle of herpes simplex virus polypeptides appear as immediate early, early and late proteins. We classified the 65 K DNA binding protein as an early (beta-) protein by comparing its detectibility with that of two well defined proteins the ICP 4 (known as immediate early protein) and the ICP 8 (known as early protein).
Schenk
P
P
Institut für Virologie der Freien Universität Berlin.
Ludwig
H
H
D000818:Animals; D015153:Blotting, Western; D004268:DNA-Binding Proteins / Q000378:metabolism*; D005455:Fluorescent Antibody Technique; D008970:Molecular Weight; D009687:Nuclear Proteins / Q000378:metabolism*; D018139:Simplexvirus / Q000254:growth & development*; D013997:Time Factors; D014709:Vero Cells; D014764:Viral Proteins / Q000378:metabolism*; D014779:Virus Replication
D004268:DNA-Binding Proteins; D009687:Nuclear Proteins; D014764:Viral Proteins