title: The presence of three neuroactive peptides in putative glycinergic amacrine cells of an avian retina.
abstract: Amacrine cells are retinal interneurons which serve to mediate transmission between bipolar and ganglion cells. To date, in addition to several classical neurotransmitters, a number of neuroactive peptides have been localized to these cells. We have previously demonstrated in the chicken that both peptide-transmitter and peptide-peptide colocalization exists in some amacrine cells. In this report, we show that 3 neuroactive peptides (enkephalin, neurotensin and somatostatin) are present in subpopulations of amacrine cells which also possess a high affinity uptake system for glycine. These observations suggest that the simultaneous visualization by autoradiography of [3H]glycine-uptake and immunocytochemistry of peptides may be useful for distinguishing between different types of putative glycinergic amacrine cells.
authors.forename: C B
authors.initials: CB
authors.lastname: Watt
authors.forename: H B
authors.initials: HB
authors.lastname: Li
authors.forename: D M
authors.initials: DM
authors.lastname: Lam
mesh_terms: D000818:Animals; D001345:Autoradiography; D002645:Chickens / Q000378:metabolism*; D004745:Enkephalins / Q000378:metabolism; D005998:Glycine / Q000378:metabolism; D007395:Interneurons / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D009496:Neurotensin / Q000378:metabolism; D012160:Retina / Q000378:metabolism*; D013004:Somatostatin / Q000378:metabolism; D009435:Synaptic Transmission
chemical_list: D004745:Enkephalins; D009419:Nerve Tissue Proteins; D009496:Neurotensin; D013004:Somatostatin; D005998:Glycine