Immunoreactive dynorphin-like material in rat pituitary after ovariectomy.
Ovariectomy caused a significant increase of immunoreactive dynorphin-like material (IR-DYAN) in the anterior pituitary lobe of intact as well as of medial basal hypothalamus-lesioned rats. No change of IR-DYAN was observed in the neurointermediate lobe of the gland or in the hypothalamus. Estradiol benzoate reversed the increase of anterior pituitary IR-DYAN induced by ovariectomy and caused a reduction in sham-ovariectomized rats.
Spampinato
S
S
Candeletti
S
S
Russo
A
A
Leanza
G
G
Stanzani
S
S
Ferri
S
S
D000818:Animals; D004399:Dynorphins / Q000032:analysis*; D004958:Estradiol / Q000494:pharmacology; D005260:Female; D007031:Hypothalamus / Q000032:analysis; D010052:Ovariectomy; D010903:Pituitary Gland, Anterior / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains
D004958:Estradiol; D004399:Dynorphins