Influence of psychosomatic stress in pregnant guinea-pigs on fetal lipid metabolism.
After a psychosomatic stress applied to pregnant guinea-pigs, 7 or 1 day before term, plasma cortisol and non-esterified fatty acid levels increased immediately in mother and fetus. Plasma levels of cortisol and non-esterified fatty acids in newborns of mothers stressed 1 day before term were lower than in newborns of control mothers. The prenatal stress changed composition of triacylglycerol and phospholipids in newborn liver by inhibiting the postnatal increase of triacylglycerol and phospholipid stearic acid and by inhibiting the postnatal decrease in phospholipid palmitic, palmitoleic, linolenic and arachidonic acids.
Dauprat
P
P
Aurousseau
B
B
Bauchart
D
D
Dalle
M
M
Delost
P
P
D000818:Animals; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000378:metabolism; D005229:Fatty Acids, Monounsaturated; D005231:Fatty Acids, Unsaturated / Q000097:blood; D005260:Female; D005333:Fetus / Q000378:metabolism*; D006168:Guinea Pigs; D006854:Hydrocortisone / Q000097:blood; D008042:Linolenic Acids / Q000378:metabolism; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism; D019308:Palmitic Acid; D010169:Palmitic Acids / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism; D011247:Pregnancy; D013312:Stress, Physiological / Q000378:metabolism*; D013997:Time Factors; D014280:Triglycerides / Q000378:metabolism; D017962:alpha-Linolenic Acid
D001095:Arachidonic Acids; D005229:Fatty Acids, Monounsaturated; D005231:Fatty Acids, Unsaturated; D008042:Linolenic Acids; D010169:Palmitic Acids; D010743:Phospholipids; D014280:Triglycerides; D017962:alpha-Linolenic Acid; C008757:palmitoleic acid; D016718:Arachidonic Acid; D019308:Palmitic Acid; D006854:Hydrocortisone