[Effect of astemizole on psychophysical performance].
Within four partial clinical trials of Astemizole versus placebo it has been proved, that no differences regarding the driving ability and the safe operation of machinery could be detected. Furthermore it could be observed, that there was no disadvantageous efficacy concerning subjective behaviour and that Astemizole did not potentiate Diazepam and alcohol.
Moser
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D000428:Alcohol Drinking; D001143:Arousal / Q000187:drug effects; D016589:Astemizole; D001334:Automobile Driving; D001562:Benzimidazoles / Q000009:adverse effects*; D002986:Clinical Trials as Topic; D003975:Diazepam / Q000009:adverse effects; D004311:Double-Blind Method; D004357:Drug Synergism; D006634:Histamine H1 Antagonists / Q000009:adverse effects*; D006801:Humans; D007665:Ketotifen / Q000009:adverse effects; D011597:Psychomotor Performance / Q000187:drug effects*; D011930:Reaction Time / Q000187:drug effects
D001562:Benzimidazoles; D006634:Histamine H1 Antagonists; D016589:Astemizole; D003975:Diazepam; D007665:Ketotifen
Die Wirkung von Astemizol auf die psychophysischen Leistungen.