Proton NMR characteristics of a biological system useful for developing in vivo spectroscopy and imaging techniques for tumors.
A model system for in vivo proton NMR studies consisting of a transplantable tumor growing on a rat's tail was investigated at 90 MHz using a high-resolution Fourier transform spectrometer. Spectra were obtained, relaxation times were measured, and the spatial distributions of proton signal intensities were estimated. We conclude that the model could be used for developing both spectroscopy and imaging approaches.
Block
R E
RE
Department of Radiology, Mount Sinai Medical Center, Miami Beach, Florida 33140.
Parekh
B
B
Menditto
R
R
D000818:Animals; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008325:Mammary Neoplasms, Experimental / Q000378:metabolism*; D009368:Neoplasm Transplantation; D011522:Protons; D051381:Rats; D011916:Rats, Inbred F344
D011522:Protons