[Interaction of the GABA-ergic system with the dopaminergic and serotoninergic in immunomodulation].
In CBA mice immunized with sheep red blood cells, the GABA-ergic system was found to act on the immunogenesis depending on the monoaminergic systems activity. The dopaminergic system stimulating immunogenesis is predominant in activation of the GABA-ergic system, whereas the serotoninergic system mediating the inhibition of the immune response is predominant in conditions of the GABA-ergic system blockade.
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D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D007114:Immunization; D051379:Mice; D008808:Mice, Inbred CBA; D011954:Receptors, Dopamine / Q000187:drug effects / Q000276:immunology*; D011963:Receptors, GABA-A / Q000187:drug effects / Q000276:immunology*; D011985:Receptors, Serotonin / Q000187:drug effects / Q000276:immunology*; D012397:Rosette Formation; D013154:Spleen / Q000187:drug effects / Q000276:immunology; D013997:Time Factors
D000276:Adjuvants, Immunologic; D011954:Receptors, Dopamine; D011963:Receptors, GABA-A; D011985:Receptors, Serotonin
Vzaimodeĭstvie GAMK-ergicheskoĭ sistemy s dopaminergicheskoĭ i serotoninergicheskoĭ v immunomoduliatsii.