title: Evaluating CPPD crystal deposition, an important disease of aging.
abstract: Calcium pyrophosphate dihydrate deposition disease is a spectrum of disease including asymptomatic chondrocalcinosis, pseudogout, and chronic arthropathy. Its frequency increases with advancing age and is found very commonly in the aged. Underlying metabolic illnesses are occasionally identifiable. Differentiation from other causes of arthritis that it may mimic is often important and possible on clinical grounds, radiographic examination, and synovial fluid analysis. Prognosis is variable and treatment may include analgesics, nonsteroidal anti-inflammatory drugs, colchicine, and intra-articular corticosteroids.
authors.affiliation: Oregon Health Sciences University, Portland.
authors.forename: R P
authors.initials: RP
authors.lastname: Bonafede
mesh_terms: D000368:Aged; D000375:Aging / Q000378:metabolism; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D002131:Calcium Pyrophosphate / Q000032:analysis / Q000378:metabolism*; D002805:Chondrocalcinosis / Q000188:drug therapy / Q000209:etiology / Q000378:metabolism* / Q000503:physiopathology; D003078:Colchicine / Q000627:therapeutic use; D003937:Diagnosis, Differential; D011756:Diphosphates / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D010003:Osteoarthritis / Q000000981:diagnostic imaging / Q000503:physiopathology; D011379:Prognosis; D011859:Radiography; D013582:Synovial Fluid / Q000032:analysis
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D011756:Diphosphates; D003078:Colchicine; D002131:Calcium Pyrophosphate