title: Late-onset adrenal hyperplasia in north Indian hirsute women.
abstract: The occurrence of late-onset congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency was studied in 60 consecutive hirsute women by means of adrenocorticotrophin (ACTH)-stimulated serum 17-hydroxyprogesterone (17-OHP) levels. Five (8.3%) women had an exaggerated response (ACTH-stimulated 17-OHP 3,160 +/- 560 ng/dl). All of them had regular periods and 3 were virilized. The other 2 were indistinguishable from those with idiopathic hirsutism or polycystic ovarian disease.
authors.affiliation: Department of Endocrinology and Metabolism, All-India Institute of Medical Sciences, New Delhi.
authors.forename: A
authors.initials: A
authors.lastname: Mithal
authors.forename: A C
authors.initials: AC
authors.lastname: Ammini
authors.forename: M M
authors.initials: MM
authors.lastname: Godbole
authors.forename: M L
authors.initials: ML
authors.lastname: Khurana
authors.forename: D
authors.initials: D
authors.lastname: Raj
authors.forename: M G
authors.initials: MG
authors.lastname: Karmarkar
authors.forename: M M
authors.initials: MM
authors.lastname: Ahuja
mesh_terms: D019326:17-alpha-Hydroxyprogesterone; D000293:Adolescent; D000312:Adrenal Hyperplasia, Congenital / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000328:Adult; D005260:Female; D006628:Hirsutism / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D006908:Hydroxyprogesterones / Q000097:blood*; D007194:India
chemical_list: D006908:Hydroxyprogesterones; D019326:17-alpha-Hydroxyprogesterone; D000324:Adrenocorticotropic Hormone