Phaclofen antagonizes GABA at autoreceptors regulating release in rat cerebral cortex.
Bonanno
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Istituto di Farmacologia e Farmacognosia, Università degli Studi di Genova, Italy.
Fontana
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G
Raiteri
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M
D000818:Animals; D001418:Baclofen / Q000031:analogs & derivatives* / Q000494:pharmacology; D001640:Bicuculline / Q000494:pharmacology; D002540:Cerebral Cortex / Q000187:drug effects / Q000378:metabolism*; D018756:GABA Antagonists; D066298:In Vitro Techniques; D008297:Male; D009118:Muscimol / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D011963:Receptors, GABA-A / Q000187:drug effects*; D013574:Synaptosomes / Q000187:drug effects / Q000378:metabolism
D018756:GABA Antagonists; D011963:Receptors, GABA-A; C052329:phaclofen; D009118:Muscimol; D001418:Baclofen; D001640:Bicuculline