title: Formal relations between Om mutants and their suppressors in Drosophila ananassae.
abstract: Optic morphology (Om) mutants associated with insertions of the tom transposable element at each of three tested loci are neomorphs as defined by the phenotypic equivalence of +/+/Om with +/Om and of +/Om/Om with Om/Om. Mutants behaving as suppressors of Om mutants and mapping to at least six loci are recovered from the same source and in similar frequency as Om mutants. The semidominant and nonpleiotropic suppressors at four of the six loci display defective eye phenes themselves, and the phenotypically normal mutants at a fifth locus are suspected alleles of a gene represented by recessive furrowed eye mutants. These and other properties imply that the suppressors, like suppressible Om mutants, are neomorphic due to insertion of the tom element into a hypothetical sequence they share with other members of a set of genes involved in development of the eye. Concurrently premature expression of both the suppressor and suppressed mutants would allow interaction of their products just as in normal development.
authors.affiliation: Department of Biology, College of Wooster, Ohio 44691.
authors.forename: C W
authors.initials: CW
authors.lastname: Hinton
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D004251:DNA Transposable Elements; D004330:Drosophila / Q000235:genetics* / Q000254:growth & development; D005123:Eye / Q000033:anatomy & histology; D005260:Female; D008297:Male; D010641:Phenotype; D013489:Suppression, Genetic; D014960:X Chromosome
chemical_list: D004251:DNA Transposable Elements