Evaluation on the treatment of morphine addiction by acupuncture Chinese herbs and opioid peptides.
Experimental studies on the effects of acupuncture, combined Chinese herbs, and opioid peptides on morphine withdrawal symptoms were carried out in 119 addicted rats. Electroacupuncture was found to be the most effective method as it reduced the morphine withdrawal scores to -85%. The combined herbs, Qiang Huo, Gou Teng, Chuan Xion, Fu Zi and Yan Hu Suo suppressed the withdrawal scores of -68%. The opioid peptides, endorphin, enkephalin, and dynorphin, produced marked sedative effect and alleviated the withdrawal symptoms, reducing the scores from -28% to -74%. It is suggested that acupuncture and herbs, being non-opiate and having less side effect, might be used as alternative or supplementary treatment on morphine addiction.
Yang
M M
MM
Kwok
J S
JS
D015670:Acupuncture Therapy; D000818:Animals; D003131:Combined Modality Therapy; D004399:Dynorphins / Q000627:therapeutic use; D004723:Endorphins / Q000627:therapeutic use*; D004744:Enkephalin, Methionine / Q000627:therapeutic use; D008516:Medicine, Chinese Traditional; D008518:Medicine, East Asian Traditional; D009020:Morphine / Q000009:adverse effects*; D010946:Plants, Medicinal; D051381:Rats; D011919:Rats, Inbred Strains; D013375:Substance Withdrawal Syndrome / Q000628:therapy*; D001615:beta-Endorphin
D004723:Endorphins; D004744:Enkephalin, Methionine; D001615:beta-Endorphin; D004399:Dynorphins; D009020:Morphine