Two-component responses to sympathetic nerve stimulation in the rat tail artery.
Membrane potential and tension were recorded simultaneously from the smooth muscle of the rat tail artery. A single stimulus to the perivascular nerves caused a tension transient. The tension transient had two components, one due to a muscle action potential and one due to alpha-adrenoceptor activation. During trains of stimuli most of the tension was due to alpha-receptor activation, even when every stimulus caused a smooth muscle action potential.
Neild
T
T
Kotecha
N
N
D000200:Action Potentials; D000818:Animals; D001158:Arteries / Q000294:innervation*; D004558:Electric Stimulation; D008297:Male; D008564:Membrane Potentials / Q000187:drug effects; D011224:Prazosin / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects / Q000502:physiology; D013564:Sympathetic Nervous System / Q000502:physiology*; D013623:Tail / Q000098:blood supply
D011942:Receptors, Adrenergic, alpha; D011224:Prazosin