A new cell system for the study of mouse mammary tumour virus.
A stable cell line derived from mammary gland cancer of Djungarian hamster is proposed for the study of oncogenic properties of mouse mammary tumour virus (MMTV). The conditions of infection and expression of the viral genome in this cell line are described in addition to the chromosomal composition or the original and infected cells. The MMTV-infected cells showed increased colony formation in semi-solid media. The advantages of the new cell system are discussed.
Litvinov
S V
SV
Sokova
O I
OI
Kryukova
I N
IN
D000818:Animals; D002460:Cell Line; D002999:Clone Cells; D006224:Cricetinae; D005260:Female; D007621:Karyotyping; D008325:Mammary Neoplasms, Experimental / Q000382:microbiology* / Q000473:pathology; D008324:Mammary Tumor Virus, Mouse / Q000502:physiology*; D051379:Mice