Location and distribution of a receptor for the 987P pilus of Escherichia coli in small intestines.
Frozen sections of rabbit or pig small intestines were stained with fluorescein-labeled antibody specific for the 987P receptor isolated from adult rabbit small intestines. The 987P receptor was present along the entire villous surface and in goblet cells in adult rabbits, but only in goblet cells in infant rabbits. In adult rabbits, the receptor was distributed equally in the jejunum and the ileum. Material antigenically similar to the rabbit 987P receptor was demonstrated in goblet cells in neonatal piglet ileum.
Dean
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Isaacson
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D000818:Animals; D004926:Escherichia coli / Q000502:physiology*; D010861:Fimbriae, Bacterial; D005455:Fluorescent Antibody Technique; D007082:Ileum / Q000032:analysis*; D007413:Intestinal Mucosa / Q000032:analysis; D007583:Jejunum / Q000032:analysis*; D011817:Rabbits; D011971:Receptors, Immunologic / Q000032:analysis*; D013552:Swine
D011971:Receptors, Immunologic; C037872:pili, bacterial receptor