title: Lack of pathogenicity of five serotype 2 infectious bursal disease viruses in chickens.
abstract: The pathogenic potential of five strains of serotype 2 infectious bursal disease virus (IBDV) for specific-pathogen-free chickens was examined. There were no gross or microscopic lesions in the inoculated chickens. Bursa-to-body-weight ratios of IBDV-infected chickens were not significantly different from those of uninfected controls. Virus-neutralizing antibodies to IBDV of serotype 2, but not serotype 1, were detected in infected chickens. This study indicated that the serotype 2 viruses examined were infectious but not pathogenic in chickens.
authors.affiliation: Ohio Agricultural Research and Development Center, Ohio State University, Wooster 44691.
authors.forename: N M
authors.initials: NM
authors.lastname: Ismail
authors.forename: Y M
authors.initials: YM
authors.lastname: Saif
authors.forename: P D
authors.initials: PD
authors.lastname: Moorhead
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis; D002645:Chickens / Q000276:immunology / Q000382:microbiology*; D007243:Infectious bursal disease virus / Q000276:immunology / Q000472:pathogenicity*; D009500:Neutralization Tests; D012087:Reoviridae / Q000472:pathogenicity*; D012703:Serotyping / Q000662:veterinary; D013045:Species Specificity
chemical_list: D000914:Antibodies, Viral