[Modification of psychic, autonomic and metabolic reactions during examinations by a single dose of beta-receptor blockers].
18 students of human medicine were checked during their state examinations when they were or were not administered the beta-receptor blocker Propranolol. In the present examinations under psychic stress Propranolol has no ascertaining influence on the experience parameters, but on somatic reactions in the cardio-circulatory system, the haematological system as well as in the influence on a series of laboratory-chemical parameters. While slighter heart rate, lower blood pressure, a slighter decrease of the absolute number of lymphocytes and a lower plasma cortisol level refer to less distinct reactions of demand under influence of Propranolol, in the region of the lipid parameters HDL-cholesterol and LDL-cholesterol changes develop in the sense of an at least situational increased atherogenic risk.
Pietruschka
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WD
Scheuch
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D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure / Q000187:drug effects; D003402:Creatine Kinase / Q000097:blood; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007501:Iron / Q000097:blood; D007958:Leukocyte Count / Q000187:drug effects; D008055:Lipids / Q000097:blood; D008297:Male; D011433:Propranolol / Q000627:therapeutic use; D013315:Stress, Psychological / Q000188:drug therapy* / Q000503:physiopathology
D000319:Adrenergic beta-Antagonists; D001786:Blood Glucose; D008055:Lipids; D011433:Propranolol; D007501:Iron; D003402:Creatine Kinase; D006854:Hydrocortisone
Beeinflussung von psychischen, vegetativen und Stoffwechselreaktionen unter Examina durch einmalige Gabe von beta-Rezeptorenblockern.