title: Relation between consumption of alcohol and fatty acids esterifying serum cholesterol in healthy men.
abstract: The relation between consumption of alcohol (established by interview), two of its typical markers (gamma-glutamyltransferase activity and mean corpuscular volume), and the composition of fatty acids in plasma cholesterol esters was investigated in an epidemiological study of 1467 actively employed men aged 35-45. In this group of subjects mean consumption of alcohol was 34.6 (SD 25.2) g/day. Palmitoleic acid and oleic acid were positively correlated with consumption of alcohol, gamma-glutamyltransferase activity, and mean corpuscular volume, while linoleic acid was negatively correlated with these variables. When these three fatty acids, gamma-glutamyltransferase activity, mean corpuscular volume, and the fat content of the diet were introduced into a multivariate regression analysis, with consumption of alcohol as the dependent variable, only palmitoleic acid, gamma-glutamyltransferase activity, mean corpuscular volume, and the monounsaturated fat content of the diet remained significant. Palmitoleic acid seems to be an independent correlate of consumption of alcohol and could be useful in epidemiological and clinical studies as a variable of consumption.
authors.forename: J M
authors.initials: JM
authors.lastname: Warnet
authors.forename: F
authors.initials: F
authors.lastname: Cambien
authors.forename: V
authors.initials: V
authors.lastname: Vernier
authors.forename: M
authors.initials: M
authors.lastname: Pecoraro
authors.forename: C
authors.initials: C
authors.lastname: Flament
authors.forename: P
authors.initials: P
authors.lastname: Ducimetiere
authors.forename: A
authors.initials: A
authors.lastname: Jacqueson
authors.forename: J L
authors.initials: JL
authors.lastname: Richard
authors.forename: J R
authors.initials: JR
authors.lastname: Claude
mesh_terms: D000328:Adult; D000428:Alcohol Drinking; D002788:Cholesterol Esters / Q000097:blood*; D004041:Dietary Fats / Q000032:analysis; D004909:Erythrocyte Indices; D005227:Fatty Acids / Q000032:analysis*; D005229:Fatty Acids, Monounsaturated; D006801:Humans; D008297:Male; D008875:Middle Aged; D010169:Palmitic Acids / Q000032:analysis; D005723:gamma-Glutamyltransferase / Q000097:blood
chemical_list: D002788:Cholesterol Esters; D004041:Dietary Fats; D005227:Fatty Acids; D005229:Fatty Acids, Monounsaturated; D010169:Palmitic Acids; C008757:palmitoleic acid; D005723:gamma-Glutamyltransferase