title: [Phosphorylation and inhibition of gamma-glutamyl transferase activity by cAMP-dependent protein kinase].
abstract: It was shown that preparations of bovine kidney gamma-glutamyl transferase with different degree of purity are phosphorylated by cAMP-dependent protein kinase. Phosphorylation is accompanied by a simultaneous decrease of both transferase and hydrolase activities of the enzyme. Hence, gamma-glutamyltransferase may serve as a substrate and target of regulation by cAMP-dependent protein kinase.
authors.forename: L S
authors.initials: LS
authors.lastname: Kolesnichenko
authors.forename: N N
authors.initials: NN
authors.lastname: Chernov
mesh_terms: D000818:Animals; D001921:Brain / Q000201:enzymology; D002384:Catalysis; D002417:Cattle; D004591:Electrophoresis, Polyacrylamide Gel; D066298:In Vitro Techniques; D007668:Kidney / Q000201:enzymology; D010766:Phosphorylation; D011494:Protein Kinases / Q000378:metabolism*; D013552:Swine; D005723:gamma-Glutamyltransferase / Q000037:antagonists & inhibitors / Q000378:metabolism*
chemical_list: D005723:gamma-Glutamyltransferase; D011494:Protein Kinases
vernacular_title: Fosforilirovanie i tormozhenie aktivnosti gamma-glutamiltransferazy cAMP-zavisimoĭ proteinkinazoĭ.