title: Activities of amino acid metabolizing enzymes in the stomach and small intestine of developing rats.
abstract: The activities of aspartate and alanine transaminase, serine dehydratase, arginase, glutamate dehydrogenase, adenylate deaminase and glutamine synthetase were determined in the stomach and small intestine of developing rats. Despite the common embryonic origin of the intestine and stomach, their enzymes showed quite different activity levels and patterns of development, depending on their roles. Most enzyme activities were low during late intrauterine life and after birth, attaining adult levels with the change of diet at weaning. No arginase activity was found in the stomach and no changes were detected in adenylate deaminase in the stomach or intestine throughout the period studied. Alanine transaminase, serine dehydratase and, to some extent, glutamine synthetase levels, significantly higher in late intrauterine life, decreased after birth, suggesting that the foetal stomach has a transient ability to handle amino acids.
authors.forename: X
authors.initials: X
authors.lastname: Remesar
authors.forename: L
authors.initials: L
authors.lastname: Arola
authors.forename: A
authors.initials: A
authors.lastname: Palou
authors.forename: M
authors.initials: M
authors.lastname: Alemany
mesh_terms: D000659:AMP Deaminase / Q000378:metabolism; D000367:Age Factors; D000410:Alanine Transaminase / Q000378:metabolism; D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D000831:Animals, Newborn / Q000378:metabolism*; D001119:Arginase / Q000378:metabolism; D001219:Aspartate Aminotransferases / Q000378:metabolism; D005333:Fetus / Q000378:metabolism*; D005969:Glutamate Dehydrogenase / Q000378:metabolism; D005974:Glutamate-Ammonia Ligase / Q000378:metabolism; D007421:Intestine, Small / Q000196:embryology / Q000201:enzymology*; D012695:L-Serine Dehydratase / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013270:Stomach / Q000196:embryology / Q000201:enzymology*
chemical_list: D000596:Amino Acids; D005969:Glutamate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D001119:Arginase; D000659:AMP Deaminase; D012695:L-Serine Dehydratase; D005974:Glutamate-Ammonia Ligase