title: Hodgkin-cell leukaemia of B-cell origin.
abstract: A case of lymphocyte-depleted nodular sclerosing Hodgkin's disease with a terminal leukaemic phase is described. Circulating Hodgkin cells were shown to be of B-cell origin by immunological phenotyping and the demonstration of clonal immunoglobulin gene rearrangement.
authors.forename: D C
authors.initials: DC
authors.lastname: Linch
authors.forename: H M
authors.initials: HM
authors.lastname: Jones
authors.forename: N
authors.initials: N
authors.lastname: Berliner
authors.forename: K
authors.initials: K
authors.lastname: MacLennan
authors.forename: K
authors.initials: K
authors.lastname: O'Flynn
authors.forename: E R
authors.initials: ER
authors.lastname: Huehns
authors.forename: L A
authors.initials: LA
authors.lastname: Kay
authors.forename: K
authors.initials: K
authors.lastname: Goff
mesh_terms: D000368:Aged; D000911:Antibodies, Monoclonal; D001402:B-Lymphocytes / Q000145:classification / Q000276:immunology* / Q000378:metabolism / Q000648:ultrastructure; D002118:Calcium / Q000378:metabolism; D005260:Female; D006689:Hodgkin Disease / Q000235:genetics / Q000276:immunology / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007938:Leukemia / Q000235:genetics / Q000276:immunology / Q000378:metabolism / Q000473:pathology*; D010641:Phenotype; D010835:Phytohemagglutinins / Q000494:pharmacology
chemical_list: D000911:Antibodies, Monoclonal; D007136:Immunoglobulins; D010835:Phytohemagglutinins; D002118:Calcium