The influence of povidone-iodine treatment on thyroid hormones in severe burns.
Average iodine serum levels of 2.5 mg/100 ml were obtained in 10 patients with an average burn area of 50% and treated with povidone-iodine. Simultaneous measurements of the thyroid hormones failed to reveal any significant impairment of thyroid function apart from depressed T3 coupled with increased reverse T3. Similar findings were obtained with a control group of 10 multiply-injured patients. If renal function is unimpaired the resorbed iodine is quickly excreted. No clinical signs of iodine intoxication were observed.
Balogh
D
D
Bauer
M
M
Riccabona
G
G
D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D002056:Burns / Q000188:drug therapy* / Q000378:metabolism; D006801:Humans; D007455:Iodine / Q000097:blood / Q000652:urine; D011205:Povidone / Q000031:analogs & derivatives*; D011206:Povidone-Iodine / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use; D013963:Thyroid Hormones / Q000097:blood*; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D000891:Anti-Infective Agents, Local; D013963:Thyroid Hormones; D014284:Triiodothyronine; D011206:Povidone-Iodine; D007455:Iodine; D011205:Povidone; D013974:Thyroxine