[Deletional and insertional analysis of the antitumorigenicity of the plasmid R388 in Agrobacterium tumefaciens].
The study of the plasmid R388 deletional derivatives has shown the antitumorigenicity determinant of the plasmid to be contained by the tra-operon. Transposon Tn5 has been used for selection of a number of insertional mutants having lost the antitumorigenic properties. The difference in the locations of Tn5 inserts was found, all of the latter being localized within the tra-operon. The data obtained suggest the locus of the plasmid R388 responsible for its antitumorigenic properties to be located in the region of tra-genes distally to the rep-region.
Mashkovskaia
G V
GV
Denisova
T S
TS
Lovanok
E V
EV
Fomicheva
V V
VV
Kartel'
N A
NA
D015197:Carcinogenicity Tests; D002872:Chromosome Deletion; D004251:DNA Transposable Elements; D009154:Mutation; D009876:Operon; D010957:Plasmids; D015183:Restriction Mapping; D012231:Rhizobium / Q000235:genetics*
D004251:DNA Transposable Elements
Deletsionnyĭ i insertsionnyĭ analiz antionkogennosti plazmidy R388 uAgrobacterium tumefaciens.