Effect of fetal and adult bovine albumins on human lymphocyte proliferation in vitro.
Fetal and adult bovine albumins were isolated and compared with the commercially obtained fraction V of Cohn, in terms of their ability to support cell proliferation, when added as a supplement to serum-free lymphocyte cultures activated with phytohemagglutinin. It was found that fetal albumin is the least efficient of the three proteins in permitting lymphoproliferation. A difference between the kinetics of proliferation of lymphocyte cultures supplemented with albumin and with serum was also observed.
Gallango
M L
ML
Maiuri-Ranauro
P
P
Soyano
A
A
D000818:Animals; D002417:Cattle; D002478:Cells, Cultured; D005333:Fetus; D006801:Humans; D008213:Lymphocyte Activation / Q000187:drug effects*; D010835:Phytohemagglutinins; D012710:Serum Albumin, Bovine / Q000494:pharmacology*
D010835:Phytohemagglutinins; D012710:Serum Albumin, Bovine