Efficacy of propranolol in neuroleptic-induced akathesia.
The effects of propranolol, 20 to 30 mg/day, on neuroleptic-induced akathesia were compared with those of lorazepam, 2 mg/day, and periods of no treatment. Raters were blind to treatment condition. As reported in prior open studies, propranolol was found to be dramatically effective in reducing akathesia induced by neuroleptic treatment.
Adler
L
L
Angrist
B
B
Peselow
E
E
Corwin
J
J
Rotrosen
J
J
D000328:Adult; D017109:Akathisia, Drug-Induced; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008140:Lorazepam / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011433:Propranolol / Q000627:therapeutic use*; D011595:Psychomotor Agitation / Q000188:drug therapy; D011897:Random Allocation; D012559:Schizophrenia / Q000188:drug therapy
D014150:Antipsychotic Agents; D011433:Propranolol; D008140:Lorazepam