The use of adhesives in chondrocyte transplantation surgery. Preliminary studies.
This report describes the in-vitro use of mussel adhesive protein (MAP) as a possible adjunct to chondrocyte allograft surgery. Experiments were performed to define the attachment kinetics of chondrocyte onto bone using MAP, and to assess the biocompatibility of this material in vitro. The results indicate that MAP is biocompatible and may have future clinical applications in orthopaedic procedures.
Grande
D A
DA
Department of Bioengineering, Hospital for Joint Diseases Orthopaedic Institute, New York, NY 10003.
Pitman
M I
MI
D000269:Adhesives / Q000627:therapeutic use*; D000818:Animals; D001842:Bone and Bones / Q000601:surgery*; D002356:Cartilage / Q000166:cytology / Q000637:transplantation*; D046508:Culture Techniques; D006025:Glycosaminoglycans / Q000096:biosynthesis; D007700:Kinetics; D008297:Male; D008855:Microscopy, Electron, Scanning; D011506:Proteins / Q000627:therapeutic use*; D011817:Rabbits; D014184:Transplantation, Homologous
D000269:Adhesives; D006025:Glycosaminoglycans; D011506:Proteins