Angina after aortocoronary bypass grafting: combined medical therapy including nifedipine.
A second coronary artery revascularization procedure often yields poor results. Nifedipine, a calcium antagonist, was added to the current medical therapy consisting of maximal doses of beta blockers and nitrates in a group of 18 patients who had had one revascularization procedure and subsequently had class 3 and 4 angina pectoris. The overall favorable clinical response was 72%. The average dose of nifedipine to achieve a clinical response was 90 mg/day. Left ventricular function improved with time. We believe nifedipine is an important adjunct in the management of angina after coronary bypass operation.
Hanger
K H
KH
Assey
M E
ME
D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage; D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000188:drug therapy* / Q000601:surgery; D001026:Coronary Artery Bypass; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000008:administration & dosage* / Q000009:adverse effects; D005996:Nitroglycerin / Q000008:administration & dosage; D011183:Postoperative Complications / Q000188:drug therapy; D012008:Recurrence
D000319:Adrenergic beta-Antagonists; D005996:Nitroglycerin; D009543:Nifedipine