Phenyl-t-butylnitrone, a free radical spin-trapping agent, inhibits acetylcholine-induced relaxation and cyclic GMP accumulation in rat thoracic aorta.
Sata
T
T
Kubota
E
E
Yoshitake
J
J
D000109:Acetylcholine / Q000037:antagonists & inhibitors*; D000818:Animals; D001013:Aorta, Thoracic / Q000187:drug effects / Q000378:metabolism; D006152:Cyclic GMP / Q000378:metabolism*; D003497:Cyclic N-Oxides; D005609:Free Radicals; D066298:In Vitro Techniques; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects*; D009126:Muscle Relaxation / Q000187:drug effects*; D009131:Muscle, Smooth, Vascular / Q000187:drug effects*; D009589:Nitrogen Oxides / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
D003497:Cyclic N-Oxides; D005609:Free Radicals; D009589:Nitrogen Oxides; C029217:phenyl-N-tert-butylnitrone; D006152:Cyclic GMP; D000109:Acetylcholine