The effects of oxymetazoline on secretion of protein and some electrolytes by rat submandibular and parotid glands.
Oxymetazoline is a potent secretagogue for the salivary glands of rats. In the parotid gland, it activates preferentially alpha-adrenoceptors. As for the submandibular glands, it activates alpha-adrenoceptors at relatively low doses but at higher doses it allows secretion of new types of proteins.
Abe
K
K
Dawes
C
C
D000818:Animals; D007093:Imidazoles / Q000494:pharmacology*; D008297:Male; D008970:Molecular Weight; D010109:Oxymetazoline / Q000494:pharmacology*; D010306:Parotid Gland / Q000378:metabolism; D011506:Proteins / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012463:Saliva / Q000378:metabolism; D012469:Salivary Glands / Q000378:metabolism*; D012472:Salivation / Q000187:drug effects; D013363:Submandibular Gland / Q000378:metabolism
D007093:Imidazoles; D011506:Proteins; D010109:Oxymetazoline