[Effect of the blockade of alpha- and beta adrenergic receptors on the release of hemocoagulating compounds from the intestine into the blood].
In acute experiments on cats, tropaphen (alpha-adrenoreceptor blocking agent) sharply increased the release of antithromboplastins into the intestinal vessels. The beta-adrenoreceptor blocking agent obsidan inhibited the antithromboplastin release. Both agents practically did not affect the intensity of release of other factors of blood coagulation and fibrinolysis. The control of antithromboplastin release in the intestine seems to occur with active participation of structures close by their features to alpha- and beta-adrenoreceptors.
Golyshenkov
S P
SP
D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology*; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects*; D002199:Capillary Permeability / Q000187:drug effects; D002415:Cats; D005260:Female; D005342:Fibrinolysis / Q000187:drug effects; D066298:In Vitro Techniques; D007421:Intestine, Small / Q000378:metabolism*; D008297:Male; D011433:Propranolol / Q000494:pharmacology; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects*; D011943:Receptors, Adrenergic, beta / Q000187:drug effects*; D013925:Thromboplastin / Q000037:antagonists & inhibitors / Q000378:metabolism*; D014326:Tropanes / Q000037:antagonists & inhibitors / Q000494:pharmacology
D000317:Adrenergic alpha-Antagonists; D000319:Adrenergic beta-Antagonists; D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D014326:Tropanes; C009599:tropodifene; D013925:Thromboplastin; D011433:Propranolol
Vliianie blokady alpha- i beta-adrenoretseptorov na vydelenie kishechnikom tkanevykh gemokoaguliruiushchikh soedineniĭ v krovenosnoe ruslo.