title: Substance abuse: clinical identification and management.
abstract: Substance abuse is a significant health problem in the adolescent population. Prevention is a formidable challenge, but attempts at discouraging experimentation in early adolescence and the promotion of healthy adult role models may be effective strategies. Questions that may elicit a history suggestive of abuse should be a routine part of the adolescent medical history. Pediatricians should be familiar with the important clinical findings resulting from intoxication with the various substances of abuse and should be able to recognize the "telltale" signs of abuse. Effective management is based on attention to the basics of life support, careful attention to the physical findings, and judicious use of specific therapeutic agents. Above all, a compassionate attitude should prevail if acute-phase recovery and long-term rehabilitation are to be successful.
authors.forename: A
authors.initials: A
authors.lastname: Kulberg
mesh_terms: D000042:Absorption; D000293:Adolescent; D000328:Adult; D000435:Alcoholic Intoxication / Q000378:metabolism / Q000503:physiopathology; D000662:Amphetamines; D014151:Anti-Anxiety Agents / Q000378:metabolism / Q000506:poisoning; D001569:Benzodiazepines; D003042:Cocaine / Q000378:metabolism / Q000506:poisoning*; D003937:Diagnosis, Differential; D005260:Female; D005334:Fever / Q000139:chemically induced / Q000628:therapy; D005947:Glucose / Q000627:therapeutic use; D006213:Hallucinogens; D006801:Humans; D007022:Hypotension / Q000139:chemically induced / Q000188:drug therapy; D013287:Illicit Drugs / Q000378:metabolism / Q000506:poisoning*; D008238:Lysergic Acid Diethylamide / Q000506:poisoning; D002189:Marijuana Abuse / Q000503:physiopathology; D008635:Mescaline / Q000506:poisoning; D008702:Methaqualone / Q000378:metabolism / Q000506:poisoning; D009145:Mushroom Poisoning / Q000503:physiopathology; D009270:Naloxone / Q000627:therapeutic use; D009294:Narcotics; D009573:Nitrites / Q000506:poisoning; D011041:Poisoning; D012997:Solvents / Q000506:poisoning; D019966:Substance-Related Disorders / Q000378:metabolism / Q000503:physiopathology*
chemical_list: D000662:Amphetamines; D014151:Anti-Anxiety Agents; D006213:Hallucinogens; D013287:Illicit Drugs; D009294:Narcotics; D009573:Nitrites; D012997:Solvents; D001569:Benzodiazepines; D009270:Naloxone; D008702:Methaqualone; D008238:Lysergic Acid Diethylamide; D003042:Cocaine; D005947:Glucose; D008635:Mescaline