Immunohistochemical evidence for phenylethanolamine-N-methyltransferase-positive/tyrosine hydroxylase-negative neurones in the retina and the posterior hypothalamus of the rat.
Phenylethanolamine-N-methyltransferase (PNMT)-immunoreactive neurons were observed in the inner nuclear layer of the rat retina, apparently giving rise to fiber networks mainly in layer 3 of the inner plexiform layer. These neurons did not seem to contain tyrosine hydroxylase (TH)-like or dopamine-beta-hydroxylase (DBH)-like immunoreactivity and were much smaller and more numerous than the previously described TH-positive dopamine neurons. PNMT-positive, but TH- and DBH-negative neurons were also observed in small numbers in the basal posterior hypothalamus.
Foster
G A
GA
Hökfelt
T
T
Coyle
J T
JT
Goldstein
M
M
D000818:Animals; D004299:Dopamine beta-Hydroxylase / Q000378:metabolism*; D005455:Fluorescent Antibody Technique; D007031:Hypothalamus / Q000201:enzymology*; D007034:Hypothalamus, Posterior / Q000201:enzymology*; D008297:Male; D009474:Neurons / Q000201:enzymology; D010625:Phenylethanolamine N-Methyltransferase / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012160:Retina / Q000201:enzymology*; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism*
D014446:Tyrosine 3-Monooxygenase; D004299:Dopamine beta-Hydroxylase; D010625:Phenylethanolamine N-Methyltransferase