[Effect of the microiontophoretic injection of AMP and cAMP on the calcium current in the dialyzed neuron of the edible snail].
The effect of microiontophoretic injection of AMP and cAMP on the calcium current was investigated in dialyzed snail neurons. It was found that microiontophoretic injection of AMP restores calcium current after its "washout" during the dialysis and enhances its stability. In this case the current-voltage characteristic was shifted by 10 mV in the depolarizing direction. Under these conditions the iontophoretic cAMP injection into a dialyzed neuron produced a reversible decrease of the calcium current.
Kononenko
N I
NI
Shcherbatko
A D
AD
D000249:Adenosine Monophosphate / Q000494:pharmacology*; D000818:Animals; D015220:Calcium Channels / Q000187:drug effects* / Q000502:physiology; D000242:Cyclic AMP / Q000494:pharmacology*; D003956:Dialysis; D006372:Helix, Snails / Q000187:drug effects*; D007478:Iontophoresis; D008564:Membrane Potentials / Q000187:drug effects; D008839:Microelectrodes; D008845:Microinjections; D009474:Neurons / Q000187:drug effects* / Q000502:physiology
D015220:Calcium Channels; D000249:Adenosine Monophosphate; D000242:Cyclic AMP
Vliianie mikroionoforeticheskoĭ in''ektsiĭ AMF i tsAMF na kal'tsievyĭ tok v dializirovannom neĭrone vinogradnoĭ ulitki.