Time course of urinary excretion of intraportal ammonia as uric acid and ammonia in chickens fed low- or high-protein diet.
15N-ammonia was intraportally infused for 6 hr into chickens fed 5% or 20% protein diet to examine the time course of urinary excretion of intraportal ammonia and dietary effects on it. Urinary ammonia increased linearly for the first hour to the same extent in both dietary groups and thereafter further in the low-protein group. Urinary uric acid derived from the intraportal ammonia adaptively increased and reached a steady state level within 1.5 hr. This level was four times higher in the high-protein group. The infused ammonia was excreted into urine as both ammonia and uric acid, in relatively high proportions in the chickens fed the low-protein diet but was almost all excreted as uric acid in those fed the high-protein diet.
Karasawa
Y
Y
D000641:Ammonia / Q000008:administration & dosage / Q000652:urine*; D000818:Animals; D002645:Chickens; D004044:Dietary Proteins; D007263:Infusions, Parenteral; D008297:Male; D009587:Nitrogen Isotopes; D011169:Portal Vein; D014527:Uric Acid / Q000652:urine*
D004044:Dietary Proteins; D009587:Nitrogen Isotopes; D014527:Uric Acid; D000641:Ammonia