title: Efficacy and safety of two different dose levels of ganciclovir for the treatment of cytomegalovirus chorioretinitis in AIDS patients.
abstract: The effect of different dosages of ganciclovir on proved cytomegalovirus chorioretinitis was tested in a randomized trial on 11 homosexual men with AIDS. The effect of 5 mg/kg/day was as good as 10 mg/kg/day. The lower dosage had less toxicity.
authors.affiliation: Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark.
authors.forename: J
authors.initials: J
authors.lastname: Gaub
authors.forename: A G
authors.initials: AG
authors.lastname: Poulsen
authors.forename: C
authors.initials: C
authors.lastname: Pedersen
authors.forename: S
authors.initials: S
authors.lastname: Tinning
authors.forename: K
authors.initials: K
authors.lastname: Højgaard
authors.forename: M H
authors.initials: MH
authors.lastname: Thomson
authors.forename: V
authors.initials: V
authors.lastname: Faber
authors.forename: J O
authors.initials: JO
authors.lastname: Nielsen
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000212:Acyclovir / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000328:Adult; D000998:Antiviral Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D002825:Chorioretinitis / Q000188:drug therapy* / Q000209:etiology; D002986:Clinical Trials as Topic; D003586:Cytomegalovirus Infections / Q000188:drug therapy* / Q000209:etiology; D015774:Ganciclovir; D006801:Humans; D008297:Male; D008875:Middle Aged; D011897:Random Allocation
chemical_list: D000998:Antiviral Agents; D015774:Ganciclovir; D000212:Acyclovir