title: [Intensive psychopharmacologic therapy of slowly-progressive schizophrenia].
abstract: The authors analyze the results of psychopharmacotherapy of 120 patients with slowly progressive schizophrenia characterized by a high resistance to the treatment. Two new methods of the intensive therapy of such conditions (discrete and daily intravenous drip of tranquilizers in conjunction with low doses of neuroleptics) are described. The pharmacological and pharmacokinetic substantiation of each of the two techniques is presented. Clinical indications for their use have been elaborated.
authors.forename: A B
authors.initials: AB
authors.lastname: Smulevich
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Vorob'ev
authors.forename: E B
authors.initials: EB
authors.lastname: Dubnitskaia
authors.forename: V I
authors.initials: VI
authors.lastname: Maksimov
authors.forename: V N
authors.initials: VN
authors.lastname: Novikov
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002707:Chlordiazepoxide / Q000008:administration & dosage; D003975:Diazepam / Q000008:administration & dosage; D005260:Female; D005476:Fluphenazine / Q000008:administration & dosage / Q000031:analogs & derivatives; D006801:Humans; D007263:Infusions, Parenteral; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000188:drug therapy*; D013577:Syndrome; D014291:Trimeprazine / Q000008:administration & dosage
chemical_list: D014150:Antipsychotic Agents; D002707:Chlordiazepoxide; D014291:Trimeprazine; C011825:fluphenazine depot; D003975:Diazepam; D005476:Fluphenazine
vernacular_title: Intensivnaia psikhofarmakologicheskaia terapiia maloprogredientnoĭ shizofrenii.