Flow cytometric analysis of the maldescended testis.
Flow cytometric measurements of the cellular DNA contents of 16 testicular biopsies of 15 patients with maldescended testes were performed. 2 patients were children. 11 patients of pubescent or adult age had no haploid germ cells in the tissue of their maldescended testis. One patient with a testis mobilis had about a normal percentage of haploid germ cells. In one patient a malignant tumor was detected unexpectedly by an aneuploid stem line at 2.2 c. Flow cytometric analysis of human testicular biopsy material is an easy and a fast way to quantify the function of spermatogenesis and detect malignancies.
Hacker-Kolm
U
U
Kleinhans
G
G
Göhde
W
W
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002648:Child; D003456:Cryptorchidism / Q000473:pathology*; D004247:DNA / Q000032:analysis; D005434:Flow Cytometry; D006801:Humans; D008297:Male; D013091:Spermatogenesis; D013736:Testicular Neoplasms / Q000473:pathology; D013737:Testis / Q000473:pathology*
D004247:DNA