[Combined propyphenazone and codeine poisoning in childhood (analysis of 6 patients with Spasmoplus poisoning)].
The case histories are presented of 6 patients with accidental poisoning by Spasmoplus suppositories. The main toxic constituents are codeine and the pyrazolone derivative, propyphenazone. All patients had symptoms of codeine intoxication with somnolence, miosis and oedema, 2 patients had also symptoms of prophyphenazone intoxication with hypotension, coma and convulsions. 1 patient died during the acute stage in a state of shock, with arrhythmia, and asystole.
Grubbauer
H M
HM
Deutsch
J
J
Trop
M
M
Sacher
M
M
Dremsek
P
P
D000632:Aminopyrine / Q000506:poisoning*; D000701:Analgesics, Opioid / Q000506:poisoning*; D001463:Barbiturates / Q000506:poisoning*; D001794:Blood Pressure / Q000187:drug effects; D002675:Child, Preschool; D003061:Codeine / Q000506:poisoning*; D004158:Diphenylacetic Acids / Q000506:poisoning*; D004338:Drug Combinations / Q000506:poisoning; D005260:Female; D006323:Heart Arrest / Q000139:chemically induced; D006801:Humans; D007223:Infant; D008297:Male; D012640:Seizures / Q000139:chemically induced; D013488:Suppositories
D000701:Analgesics, Opioid; D001463:Barbiturates; D004158:Diphenylacetic Acids; D004338:Drug Combinations; D013488:Suppositories; C092752:spasmoplus; D000632:Aminopyrine; D003061:Codeine
Kombinierte Prophyphenazon- und Codeinvergiftung im Kindesalter (Analyse von 6 Patienten mit Spasmoplus-Vergiftung).