Alprazolam withdrawal delirium unresponsive to diazepam: case report.
A case is presented in which a 68-year-old man became delirious after being withdrawn from a low dosage of alprazolam. The delirium was not affected by administration of alprazolam. The authors suggest that alprazolam may have enhanced specificity for a subpopulation of benzodiazepine receptors.
Zipursky
R B
RB
Baker
R W
RW
Zimmer
B
B
D000368:Aged; D000525:Alprazolam; D014151:Anti-Anxiety Agents / Q000009:adverse effects* / Q000378:metabolism / Q000627:therapeutic use; D001569:Benzodiazepines / Q000009:adverse effects* / Q000378:metabolism / Q000627:therapeutic use; D003693:Delirium / Q000139:chemically induced* / Q000188:drug therapy; D003975:Diazepam / Q000627:therapeutic use*; D006207:Half-Life; D006801:Humans; D008297:Male; D011963:Receptors, GABA-A / Q000187:drug effects; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy / Q000209:etiology*
D014151:Anti-Anxiety Agents; D011963:Receptors, GABA-A; D001569:Benzodiazepines; D003975:Diazepam; D000525:Alprazolam