title: Prevention of atheromatous heart disease.
abstract: Five thousand patients of atheromatous heart disease, presented as angina pectoris, were studied over a period of five years. After adding the 'Husk of Isabgol' and 'aloe vera' (an indigenous plant known as ghee-guar-ka-paththa) to the diet, a marked reduction in total serum cholesterol, serum triglycerides, fasting and post prandial blood sugar level in diabetic patients, total lipids and also increase in HDL were noted. Simultaneously the clinical profile of these patients showed reduction in the frequency of anginal attacks and gradually, the drugs, like verapamil, nifedipine, beta-blockers and nitrates, were tapered. The patients, most benefitted, were diabetics (without adding any antidiabetic drug). The exact mechanism of the action of the above two substances is not known, but it appears, that probably they act by their high fibre contents. Both these substances need further evaluation. The most interesting aspect of the study was that no untoward side effect was noted and all the five thousand patients are surviving till date.
authors.forename: O P
authors.initials: OP
authors.lastname: Agarwal
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage; D000328:Adult; D000368:Aged; D000504:Aloe; D000787:Angina Pectoris / Q000517:prevention & control*; D001786:Blood Glucose / Q000032:analysis; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D003920:Diabetes Mellitus / Q000628:therapy; D004232:Diuretics / Q000008:administration & dosage; D004305:Dose-Response Relationship, Drug; D005080:Exercise Test; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000628:therapy; D007194:India; D007548:Isosorbide Dinitrate / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D010946:Plants, Medicinal; D014280:Triglycerides / Q000097:blood; D014700:Verapamil / Q000008:administration & dosage
chemical_list: D000319:Adrenergic beta-Antagonists; D001786:Blood Glucose; D008076:Cholesterol, HDL; D004232:Diuretics; D014280:Triglycerides; D002784:Cholesterol; D014700:Verapamil; D007548:Isosorbide Dinitrate