Complications of quinine poisoning.
Of 165 patients admitted to hospital with acute quinine poisoning 70 (42%) had visual symptoms. 19 were left with a permanent visual deficit, though none was left completely blind. 5 patients died. Bilateral stellate ganglion block was carried out on 34 patients with impaired visual acuity or blindness, but an improvement of symptoms was reported in only 4 cases. It is concluded that stellate ganglion blockade is not effective enough to justify its regular use in quinine-induced amblyopia. Quinine overdose can have serious consequences, and the drug should not be prescribed indiscriminately.
Boland
M E
ME
Roper
S M
SM
Henry
J A
JA
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D001340:Autonomic Nerve Block; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011803:Quinine / Q000097:blood / Q000506:poisoning*; D013233:Stellate Ganglion; D014786:Vision Disorders / Q000139:chemically induced / Q000628:therapy
D011803:Quinine