A possible mechanism of action of sulfasalazine and 5-aminosalicylic acid in inflammatory bowel diseases: interaction with oxygen free radicals.
Del Soldato
P
P
Campieri
M
M
Brignola
C
C
Bazzocchi
G
G
Gionchetti
P
P
Lanfranchi
G A
GA
Tamba
M
M
D000636:Aminosalicylic Acids / Q000378:metabolism*; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D003092:Colitis / Q000139:chemically induced / Q000378:metabolism*; D005609:Free Radicals; D006801:Humans; D007213:Indomethacin; D019804:Mesalamine; D051381:Rats; D012460:Sulfasalazine / Q000378:metabolism*; D013481:Superoxides / Q000378:metabolism*
D000636:Aminosalicylic Acids; D005609:Free Radicals; D013481:Superoxides; D012460:Sulfasalazine; D019804:Mesalamine; D007213:Indomethacin