title: Thyroid storm and myxedema coma.
abstract: This article describes the clinical recognition of, and pathophysiological mechanisms underlying the development of, thyroid storm and myxedema coma. Effective therapeutic management of these conditions depends on a clear understanding of the physiological adaptations occurring in hyperthyroidism and hypothyroidism, and of how precipitating events may produce these decompensated states.
authors.forename: J T
authors.initials: JT
authors.lastname: Nicoloff
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D001424:Bacterial Infections / Q000209:etiology; D001833:Body Temperature Regulation; D003128:Coma / Q000150:complications / Q000175:diagnosis / Q000378:metabolism / Q000503:physiopathology; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D007022:Hypotension / Q000628:therapy; D007037:Hypothyroidism / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D000860:Hypoxia / Q000628:therapy; D009230:Myxedema / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy; D013958:Thyroid Crisis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy
chemical_list: D000319:Adrenergic beta-Antagonists