Chorangiocarcinoma: an unusual tumour of the placenta. The missing link?
A tumour occurring in an otherwise normal placenta presented the vascularity of a mature chorangioma but was surrounded by a neoplastic trophoblastic proliferation. A chorangioma with an atypical associated trophoblastic proliferation has never been reported in any of nearly 500 cases of chorangiomas described in the literature. The possibility of a combined lesion (for which we propose the term chorangiocarcinoma) is emphasized. It cannot be excluded however that chorangiomas could be, in rare cases, true neoplasms rather than hamartomas.
Jauniaux
E
E
Laboratory of Obstetrics and Gynaecology, Hôpital Universitaire St Pierre Free University of Brussels, Belgium.
Zucker
M
M
Meuris
S
S
Verhest
A
A
Wilkin
P
P
Hustin
J
J
D006063:Chorionic Gonadotropin / Q000032:analysis; D005260:Female; D006391:Hemangioma / Q000648:ultrastructure*; D006801:Humans; D007150:Immunohistochemistry; D008853:Microscopy; D008854:Microscopy, Electron; D010920:Placenta / Q000473:pathology / Q000648:ultrastructure*; D010928:Placental Lactogen / Q000032:analysis; D011247:Pregnancy; D014328:Trophoblastic Neoplasms / Q000648:ultrastructure*; D014594:Uterine Neoplasms / Q000648:ultrastructure*
D006063:Chorionic Gonadotropin; D010928:Placental Lactogen