title: [Use of vecuronium bromide administered at a constant rate during renal transplantation].
abstract: The authors describe a technique of vecuronium bromide perfusion at constant flow used to obtain curarisation during 50 renal transplantations. The muscular effects of the drug were monitored through an electromyographical recorder, so as to adjust the perfusion rate. The dose of vecuronium bromide was 47.7 +/- 0.74 micrograms X kg-1 X h-1 (mean +/- SEM), this being lower than the dose recommended by D'Hollander (60 micrograms X kg-1 X h-1) for patients with normal renal function. Furthermore, no recurarisation was observed. Therefore, vecuronium can be considered as a satisfactory muscle relaxant in patients with renal failure, but neuromuscular monitoring appears to be a most important safety factor.
authors.forename: J P
authors.initials: JP
authors.lastname: Richard
authors.forename: J M
authors.initials: JM
authors.lastname: Conil
authors.forename: A
authors.initials: A
authors.lastname: Antonini
authors.forename: P
authors.initials: P
authors.lastname: Bareille
mesh_terms: D000328:Adult; D000762:Anesthesia Recovery Period; D000771:Anesthesia, Intravenous; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D009466:Neuromuscular Blocking Agents / Q000008:administration & dosage*; D010197:Pancuronium / Q000008:administration & dosage / Q000031:analogs & derivatives*; D014673:Vecuronium Bromide
chemical_list: D009466:Neuromuscular Blocking Agents; D014673:Vecuronium Bromide; D010197:Pancuronium
vernacular_title: Utilisation du bromure de vécuronium administré à débit constant lors des transplantations rénales.