Overdose of cyclobenzaprine, the tricyclic muscle relaxant.
A case of cyclobenzaprine (Flexeril) overdose in a 31-year-old woman is presented. The treatment rendered was analogous to treatment protocols implemented for tricyclic overdose. A review of the pharmacology of cyclobenzaprine, as well as the management of patients who overdose on this drug, is presented.
O'Riordan
W
W
Gillette
P
P
Calderon
J
J
Stennes
R L
RL
D000328:Adult; D000639:Amitriptyline / Q000031:analogs & derivatives* / Q000506:poisoning; D000929:Antidepressive Agents, Tricyclic / Q000506:poisoning*; D001639:Bicarbonates / Q000627:therapeutic use; D002606:Charcoal; D004630:Emergencies; D005260:Female; D006801:Humans; D007486:Ipecac / Q000627:therapeutic use; D009125:Muscle Relaxants, Central / Q000506:poisoning*; D012964:Sodium / Q000627:therapeutic use; D017693:Sodium Bicarbonate; D007507:Therapeutic Irrigation
D000929:Antidepressive Agents, Tricyclic; D001639:Bicarbonates; D009125:Muscle Relaxants, Central; D002606:Charcoal; D000639:Amitriptyline; C004704:cyclobenzaprine; D007486:Ipecac; D017693:Sodium Bicarbonate; D012964:Sodium