Reproduction of human and animal influenza viruses in human nasal polyp organ cultures.
Human influenza virus strains were easily grown and passaged in human nasal polyp organ cultures causing marked damage of the epithelium. Unlike to human strains, the animal influenza virus strain could be propagated for no longer than 2 or 3 passages and even the 1st passage failed to cause significant morphological changes of the epithelium cells.
Ginzburg
V P
VP
Rozina
E E
EE
Sharova
O K
OK
Ghendon YuZ
D000818:Animals; D004261:DNA Replication; D003670:Deer; D006801:Humans; D009980:Influenza A virus / Q000235:genetics / Q000254:growth & development*; D009298:Nasal Polyps / Q000382:microbiology* / Q000473:pathology; D009924:Organ Culture Techniques; D013045:Species Specificity; D014779:Virus Replication