title: Use of tocolytic drugs to reverse oxytocin-induced uterine hypertonus and fetal distress.
abstract: The use of oxytocin in labor has the inherent danger of producing uterine hyperstimulation with resultant fetal distress. When produced by gradual titration of intravenous oxytocin, discontinuation of the medication is usually sufficient to reverse the process. However, the rapid administration of a large intravenous dose of oxytocin, as occurred in this patient, may result in hypertonic uterine contractions and fetal distress unresponsive to traditional measures. The rationale for using a tocolytic drug to reverse the uterine hypertonus, produce intrauterine fetal resuscitation, and prevent cesarean section is discussed in this report.
authors.forename: J
authors.initials: J
authors.lastname: Lipshitz
authors.forename: C W
authors.initials: CW
authors.lastname: Klose
mesh_terms: D000318:Adrenergic beta-Agonists / Q000627:therapeutic use*; D000328:Adult; D005260:Female; D005316:Fetal Distress / Q000139:chemically induced / Q000188:drug therapy*; D006801:Humans; D009122:Muscle Hypertonia / Q000139:chemically induced / Q000188:drug therapy*; D010121:Oxytocin / Q000037:antagonists & inhibitors* / Q000506:poisoning; D011247:Pregnancy; D012312:Ritodrine / Q000627:therapeutic use; D014590:Uterine Contraction / Q000187:drug effects*
chemical_list: D000318:Adrenergic beta-Agonists; D010121:Oxytocin; D012312:Ritodrine