Pharmacotherapy of chronic hospitalized schizophrenics: prescription practices.
Prescription practices were examined as part of a multinational study of chronic hospitalized schizophrenic patients. The study included a total of 768 patients from 8 countries. All patients had a diagnosis (ICD-9) of schizophrenia and met defined criteria for chronic hospitalization. The patients were treated with psychotropic drugs from 6 categories, i.e., neuroleptics, antidepressants, lithium salts, anxiolytics, anticonvulsants, and antiparkinsonian medications, as well as with a variety of nonpsychotropic drugs. The majority of the patients received concurrently more than 1 neuroleptic, medications from 2 or more categories, and neuroleptics combined with other agents. Polypharmacy appeared to be universal in this population.
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D000328:Adult; D014151:Anti-Anxiety Agents / Q000008:administration & dosage; D000927:Anticonvulsants / Q000008:administration & dosage; D000928:Antidepressive Agents / Q000008:administration & dosage; D000978:Antiparkinson Agents / Q000008:administration & dosage; D014150:Antipsychotic Agents / Q000008:administration & dosage; D001938:Brazil; D002908:Chronic Disease; D003431:Cross-Cultural Comparison; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006814:Hungary; D007558:Italy; D007564:Japan; D008094:Lithium / Q000008:administration & dosage; D008297:Male; D009549:Nigeria; D010176:Panama; D011619:Psychotropic Drugs / Q000008:administration & dosage*; D012559:Schizophrenia / Q000188:drug therapy*; D014481:United States; D015022:Yugoslavia
D014151:Anti-Anxiety Agents; D000927:Anticonvulsants; D000928:Antidepressive Agents; D000978:Antiparkinson Agents; D014150:Antipsychotic Agents; D011619:Psychotropic Drugs; D008094:Lithium