title: Diarrhoea due to enterotoxigenic Clostridium perfringens: clinical features and management of a cluster of ten cases.
abstract: Clostridium perfringens has recently been shown to be associated with antibiotic-associated diarrhoea. We describe here the clinical features and management of an outbreak of diarrhoea in a Geriatric Unit. Ten cases were due to enterotoxigenic C. perfringens and in these cases there was a highly significant correlation with recent antibiotic administration (P = 0.0001). The importance of early recognition of C. perfringens as a cause of infective diarrhoea in the elderly is stressed.
authors.forename: R
authors.initials: R
authors.lastname: Williams
authors.forename: M
authors.initials: M
authors.lastname: Piper
authors.forename: P
authors.initials: P
authors.lastname: Borriello
authors.forename: F
authors.initials: F
authors.lastname: Barclay
authors.forename: A
authors.initials: A
authors.lastname: Welch
authors.forename: D
authors.initials: D
authors.lastname: Seal
authors.forename: K
authors.initials: K
authors.lastname: Sullens
mesh_terms: D000368:Aged; D003015:Clostridium Infections / Q000150:complications*; D003016:Clostridium perfringens; D003428:Cross Infection / Q000382:microbiology*; D003967:Diarrhea / Q000382:microbiology*; D004768:Enterotoxins; D005260:Female; D006801:Humans; D008297:Male
chemical_list: D004768:Enterotoxins