Some properties of adenylate cyclase which might be important for memory formation.
Analysis of the biochemical defects detected in a Drosophila memory mutant permits dissection of properties of adenylate cyclase which may play a role in elementary memory mechanisms. Of special relevance appear to be those properties which are related to the intracellular regulation of the enzyme.
Dudai
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Y
D000255:Adenosine Triphosphate / Q000378:metabolism; D000262:Adenylyl Cyclases / Q000235:genetics / Q000502:physiology*; D000494:Allosteric Regulation; D000818:Animals; D002118:Calcium / Q000494:pharmacology; D002147:Calmodulin / Q000494:pharmacology; D005576:Colforsin / Q000378:metabolism; D000242:Cyclic AMP / Q000096:biosynthesis; D004331:Drosophila melanogaster / Q000201:enzymology* / Q000235:genetics; D019204:GTP-Binding Proteins / Q000502:physiology; D007700:Kinetics; D007858:Learning / Q000502:physiology; D008274:Magnesium / Q000378:metabolism; D008568:Memory / Q000502:physiology; D009154:Mutation; D018377:Neurotransmitter Agents / Q000494:pharmacology; D013379:Substrate Specificity
D002147:Calmodulin; D018377:Neurotransmitter Agents; D005576:Colforsin; D000255:Adenosine Triphosphate; D000242:Cyclic AMP; D019204:GTP-Binding Proteins; D000262:Adenylyl Cyclases; D008274:Magnesium; D002118:Calcium