Differentiation in the complement fixation test of the viruses of tick-borne encephalitis complex by means of a type-specific soluble antigen.
Highly type-specific soluble antigens (SA) of viruses of the tick-borne encephalitis (TBE) complex were obtained by treatment of the sucrose-acetone antigens with 8 mol/l urea. Each SA reacted with the homologous serum only. The serum to SA of strain Sofyin and of Omsk haemorrhagic fever virus distinguished the TBE complex representatives; the difference between homologous serum titres was in the range of 4-5 two-fold dilution steps.
Gaidamovich SYa
Demenev
V A
VA
Obukhova
V R
VR
D000818:Animals; D000956:Antigens, Viral / Q000276:immunology*; D003168:Complement Fixation Tests; D004669:Encephalitis Viruses, Tick-Borne / Q000276:immunology*
D000956:Antigens, Viral