[Level of enkephalins and cyclic nucleotides in the myocardium in ventricular fibrillation caused by experimental myocardial infarct].
Ventricular fibrillation, caused by the occlusion of the anterior descending coronary artery, results in leu-enkephalin level decrease in ischemic and non-ischemic zones of myocardium. The fibrillation is found to induce cAMP increase in the ischemic zone and cGMP increase in the normal circulation zone. cGMP and leu-enkephalin level correlates with fibrillation duration. Enkephalins and cyclic nucleotides are suggestive of being of importance in heart rythm disturbances pathogenesis.
Maslov
L N
LN
Lishmanov
Iu B
IuB
D000818:Animals; D000242:Cyclic AMP / Q000032:analysis*; D006152:Cyclic GMP / Q000032:analysis*; D004745:Enkephalins / Q000032:analysis*; D008297:Male; D009203:Myocardial Infarction / Q000150:complications* / Q000378:metabolism; D009206:Myocardium / Q000032:analysis*; D051381:Rats; D014693:Ventricular Fibrillation / Q000209:etiology* / Q000378:metabolism
D004745:Enkephalins; D000242:Cyclic AMP; D006152:Cyclic GMP
Uroven' énkefalinov i tsiklicheskih nukleotidov v serdechnoĭ myshtse pri fibrilliatsii zheludochkov, vyzvannoĭ éksperimental'nym infarktom miokarda.