title: [Enzyme diagnostic criteria of alcoholism].
abstract: Activity of gamma-glutamyltransferase (GGT), aspartate aminotransferase (AsAT) and alanine aminotransferase was determined repeatedly for 5-10 days in the blood serum of patients with Stage I-II alcoholism (n-63) and healthy subjects (n-31). Alcoholism was associated with an elevated activity of GGT and AsAT and its dynamic fluctuations in both directions due to a change in the status of the test subject. It is stated that alcoholism in the considered enzymological manifestations is a pathogenetically unstable state. The authors recommend including the measurement of these enzymes into the complex of measures for alcoholism diagnosis.
authors.forename: I N
authors.initials: IN
authors.lastname: Piatnitskaia
authors.forename: T V
authors.initials: TV
authors.lastname: Chernobrovkina
authors.forename: I I
authors.initials: II
authors.lastname: Goriushkin
mesh_terms: D000410:Alanine Transaminase / Q000097:blood*; D000437:Alcoholism / Q000175:diagnosis*; D001219:Aspartate Aminotransferases / Q000097:blood*; D004796:Clinical Enzyme Tests; D006801:Humans; D008297:Male; D005723:gamma-Glutamyltransferase / Q000097:blood*
chemical_list: D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
vernacular_title: Enzimodiagnosticheskie kriterii alkogolizma.