title: [Selective detection of cytomegalovirus by in situ hybridization].
abstract: In two SIDS autopsy cases, in situ hybridization with biotin-labeled DNA probes was used to demonstrate a specific cytomegalovirus (CMV) infection in paraffin-embedded tissue sections. This technique represents a rapid, specific, and highly sensitive tool for the detection of CMV infections and is recommended for routine examination in other suspected viral infections, particularly in cases connected with SIDS.
authors.affiliation: Abteilung Rechtsmedizin der Medizinischen Fakultät, Rheinisch-Westfälische Technische Hochschule Aachen, Bundesrepublik Deutschland.
authors.forename: U
authors.initials: U
authors.lastname: Cremer
mesh_terms: D001483:Base Sequence; D003587:Cytomegalovirus / Q000235:genetics*; D003586:Cytomegalovirus Infections / Q000473:pathology*; D015342:DNA Probes; D006801:Humans; D007124:Immunoenzyme Techniques; D007181:Inclusion Bodies, Viral / Q000648:ultrastructure; D007223:Infant; D008297:Male; D009693:Nucleic Acid Hybridization; D010306:Parotid Gland / Q000473:pathology; D013398:Sudden Infant Death / Q000473:pathology*
chemical_list: D015342:DNA Probes
vernacular_title: Selektiver Zytomegalievirusnachweis durch "in-situ"-Hybridisierung.