[Quantitative and qualitative findings of hepatitis B virus-associated antigens, receptors and antibodies in the course of the acute phase of hepatitis B infection].
Receptors for pHSA may be the links between HBV and hepatocytes. Therefore, we evaluated the correlation between serum binding activity for pHSA during the acute phase of hepatitis B in relation to the decrease of surface antigen concentration.


METHODS
130 sera from 22 patients with acute (HBeAg-positive) hepatitis B were obtained weekly during an average interval of 7 weeks after the onset of the disease. R-pHSA were tested by RIA in 4 titre steps (1:50, 1:500, 1:5000, 1:50,000). HBsAg was analysed quantitatively by RIA according to the standard serum of the Paul-Ehrlich-Institute.
Gröticke
J W
JW
Kliniken der Freien Hansestadt Bremen, Zentralkrankenhaus St.-Jürgen-Strasse.
Gerken
G
G
Steinmann
J
J
Arnold
W
W
D000208:Acute Disease; D000328:Adult; D005260:Female; D006509:Hepatitis B / Q000276:immunology*; D006510:Hepatitis B Antibodies / Q000032:analysis*; D006511:Hepatitis B Antigens / Q000032:analysis*; D006512:Hepatitis B Core Antigens / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006513:Hepatitis B e Antigens / Q000032:analysis; D006515:Hepatitis B virus / Q000276:immunology; D006801:Humans; D008297:Male; D017457:Receptors, Albumin; D011946:Receptors, Antigen / Q000032:analysis*; D011956:Receptors, Cell Surface / Q000032:analysis
D006510:Hepatitis B Antibodies; D006511:Hepatitis B Antigens; D006512:Hepatitis B Core Antigens; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens; D017457:Receptors, Albumin; D011946:Receptors, Antigen; D011956:Receptors, Cell Surface; C030500:hepatitis B surface antigen receptor
Quantitative und qualitative Befunde Hepatitis-B-Virus-assoziierter Antigene, -Rezeptoren und -Antikörper im Verlauf der Akutphase der Hepatitis-B-Infektion.