title: Viral and cellular oncogenes in papillomavirus-associated cancers.
abstract: Papillomaviruses are one of several factors implicated in the aetiology of squamous cell carcinomas both in man and in animals. Their potential for malignant transformation is fully expressed when co-operation takes place between viral functions, cellular functions and chemical or physical co-carcinogens. This review presents a brief description of the viral transforming genes and of the cellular genes involved in transformation, and attempts to analyse how the co-operation between the two sets of genes is achieved.
authors.affiliation: Beatson Institute for Cancer Research, Bearsden, Glasgow, UK.
authors.forename: M S
authors.initials: MS
authors.lastname: Campo
mesh_terms: D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000209:etiology / Q000235:genetics; D002471:Cell Transformation, Neoplastic / Q000235:genetics; D002472:Cell Transformation, Viral; D005786:Gene Expression Regulation; D005814:Genes, Viral; D006801:Humans; D009857:Oncogenes; D027383:Papillomaviridae / Q000235:genetics* / Q000472:pathogenicity; D014412:Tumor Virus Infections / Q000209:etiology / Q000235:genetics*