The structure and hormone content of the endocrine pancreas of the one-humped camel (Camelus dromedarius).
Little is known of the blood sugar regulation in the camel and the morphology and function of its endocrine pancreas. The present paper describes the light microscopic structure and hormone content of the endocrine pancreas of the one-humped camel. Staining of pancreatic sections with haematoxylin-eosin or aldehyde-fuchsin showed numerous islets evenly distributed in all parts of the pancreas. Immunocytochemical staining for insulin or glucagon indicated that islets were predominantly composed of centrally located B-cells, surrounded by a peripheral rim of A-cells. Corresponding stainings for somatostatin or pancreatic polypeptide (PP) demonstrated that D-cells comprised only a small part of the islet volume while PP-cells were common both within and outside the islets. There were no obvious differences between the frequency of the various islet cells in different pancreatic regions. The pancreatic hormone concentrations roughly corresponded to the frequency of the different islet cell types. Insulin appeared most abundant followed by glucagon, PP and somatostatin in decreasing order. The concentrations of each of the hormones were similar in different regions of the gland. It is concluded that the endocrine pancreas of the one-humped camel is dispersed into islets of the same size and cellular composition as has been described in many other mammalian species.
Khatim
M S
MS
Gumaa
K A
KA
Petersson
B
B
Lundqvist
G
G
Grimelius
L
L
Hellerström
C
C
D000818:Animals; D002162:Camelus / Q000033:anatomy & histology*; D005934:Glucagon / Q000032:analysis*; D007328:Insulin / Q000032:analysis*; D007515:Islets of Langerhans / Q000032:analysis / Q000033:anatomy & histology* / Q000166:cytology; D010191:Pancreatic Polypeptide / Q000032:analysis*; D011863:Radioimmunoassay; D013004:Somatostatin / Q000032:analysis*
D007328:Insulin; D013004:Somatostatin; D010191:Pancreatic Polypeptide; D005934:Glucagon