A withdrawal syndrome after abrupt discontinuation of alprazolam.
A patient who received therapeutic doses of alprazolam for 8 weeks experienced a withdrawal syndrome beginning 18 hours after its abrupt discontinuation. Short-acting and minimally sedating benzodiazepines may have increased potential for withdrawal reactions.
Noyes
R
R
Clancy
J
J
Coryell
W H
WH
Crowe
R R
RR
Chaudhry
D R
DR
Domingo
D V
DV
D000328:Adult; D000379:Agoraphobia / Q000188:drug therapy; D017109:Akathisia, Drug-Induced; D000525:Alprazolam; D014151:Anti-Anxiety Agents / Q000009:adverse effects*; D001008:Anxiety Disorders / Q000188:drug therapy; D001569:Benzodiazepines / Q000009:adverse effects*; D003861:Depersonalization / Q000139:chemically induced; D001068:Feeding and Eating Disorders / Q000139:chemically induced; D005260:Female; D006801:Humans; D009325:Nausea / Q000139:chemically induced; D010200:Panic; D010469:Perceptual Distortion; D013375:Substance Withdrawal Syndrome / Q000209:etiology*
D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D000525:Alprazolam