Structure activity studies of two classes of beta-amino-amides: the search for kappa-selective opioids.
Loew
G
G
Molecular Theory Department, SRI International, Menlo Park, California 94025.
Lawson
J
J
Toll
L
L
Frenking
G
G
Berzetei-Gurske
I
I
Polgar
W
W
D000818:Animals; D001921:Brain / Q000378:metabolism; D003510:Cyclohexanes / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D003959:Diamines / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D006168:Guinea Pigs; D066298:In Vitro Techniques; D008297:Male; D008968:Molecular Conformation; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D011957:Receptors, Opioid / Q000378:metabolism*; D017473:Receptors, Opioid, kappa; D013329:Structure-Activity Relationship
D003510:Cyclohexanes; D003959:Diamines; D011957:Receptors, Opioid; D017473:Receptors, Opioid, kappa