Occurrence, distribution and nature of neuropeptide Y in the rat pancreas.
Significant quantities of a newly discovered peptide, neuropeptide Y, were found in the rat pancreas, where they were localized to nerves in the exocrine parenchyma and around arterial and ductal structures. Although unaffected by surgical parasympathectomy, the periarterial and periductal nerves were abolished by chemical sympathectomy, suggesting that NPY is partially costored with sympathetic transmitters in nerve fibers.
Carlei
F
F
Allen
J M
JM
Bishop
A E
AE
Bloom
S R
SR
Polak
J M
JM
D000818:Animals; D005455:Fluorescent Antibody Technique; D006892:Hydroxydopamines / Q000494:pharmacology; D008297:Male; D009419:Nerve Tissue Proteins / Q000032:analysis*; D009478:Neuropeptide Y; D016627:Oxidopamine; D010179:Pancreas / Q000032:analysis* / Q000098:blood supply / Q000294:innervation; D011708:Pylorus / Q000601:surgery; D051381:Rats; D011919:Rats, Inbred Strains; D013563:Sympathectomy, Chemical; D014446:Tyrosine 3-Monooxygenase / Q000032:analysis; D014628:Vagotomy
D006892:Hydroxydopamines; D009419:Nerve Tissue Proteins; D009478:Neuropeptide Y; D016627:Oxidopamine; D014446:Tyrosine 3-Monooxygenase