title: Transcription termination in animal viruses and cells.
abstract: Three experimental systems: isolated nuclei, cell-free reactions and whole cells were used for defining and characterizing cis and trans elements which regulate the block of transcription elongation in animal viruses and cells. In addition we have presented models for transcription termination within and at the end of a gene, which are consistent with the available information on the transcription bubble propagated during transcription elongation and can explain the modes of transcription termination described for various eukaryotic genes.
authors.affiliation: Department of Genetics, Weizmann Institute of Science, Rehovot, Israel.
authors.forename: O
authors.initials: O
authors.lastname: Resnekov
authors.forename: E
authors.initials: E
authors.lastname: Ben-Asher
authors.forename: E
authors.initials: E
authors.lastname: Bengal
authors.forename: M
authors.initials: M
authors.lastname: Choder
authors.forename: N
authors.initials: N
authors.lastname: Hay
authors.forename: M
authors.initials: M
authors.lastname: Kessler
authors.forename: N
authors.initials: N
authors.lastname: Ragimov
authors.forename: M
authors.initials: M
authors.lastname: Seiberg
authors.forename: H
authors.initials: H
authors.lastname: Skolnik-David
authors.forename: Y
authors.initials: Y
authors.lastname: Aloni
mesh_terms: D000260:Adenoviruses, Human / Q000235:genetics*; D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D002474:Cell-Free System; D006367:HeLa Cells / Q000378:metabolism; D006801:Humans; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D012319:RNA Polymerase II / Q000378:metabolism; D012367:RNA, Viral / Q000235:genetics / Q000302:isolation & purification; D015183:Restriction Mapping; D013539:Simian virus 40 / Q000235:genetics*; D014158:Transcription, Genetic
chemical_list: D012367:RNA, Viral; D012319:RNA Polymerase II