title: Azathioprine and cyclosporin: different tissue matching criteria needed?
abstract: Of 275 renal transplants performed over seven years in a single unit, azathioprine was the main immunosuppressive agent in 128 and cyclosporin in 147. With azathioprine graft survival was, as expected, negatively related to the number of HLA mismatches; with cyclosporin the reverse held true.
authors.forename: K R
authors.initials: KR
authors.lastname: Harris
authors.forename: N
authors.initials: N
authors.lastname: Digard
authors.forename: D C
authors.initials: DC
authors.lastname: Gosling
authors.forename: D G
authors.initials: DG
authors.lastname: Tate
authors.forename: M J
authors.initials: MJ
authors.lastname: Campbell
authors.forename: B
authors.initials: B
authors.lastname: Gardner
authors.forename: V L
authors.initials: VL
authors.lastname: Sharman
authors.forename: M
authors.initials: M
authors.lastname: Slapak
mesh_terms: D000206:Actuarial Analysis; D000293:Adolescent; D000328:Adult; D001379:Azathioprine / Q000627:therapeutic use*; D002648:Child; D003524:Cyclosporins / Q000627:therapeutic use*; D005260:Female; D006085:Graft Survival / Q000187:drug effects; D006650:Histocompatibility Testing / Q000379:methods*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D003524:Cyclosporins; D007166:Immunosuppressive Agents; D011239:Prednisolone; D001379:Azathioprine