title: Stress ulceration in the critically ill patient.
abstract: Stress ulceration is common in patients receiving intensive care. Its cause is ill defined, life threatening complications are rare but the use of H2 antagonists and antacids in prophylaxis is widespread. The development of haemorrhage and perforation appears to be related to a group of risk factors of which sepsis may be the most important.
authors.forename: A
authors.initials: A
authors.lastname: Knight
authors.forename: D
authors.initials: D
authors.lastname: Bihari
authors.forename: J
authors.initials: J
authors.lastname: Tinker
mesh_terms: D000863:Antacids / Q000009:adverse effects / Q000627:therapeutic use; D003422:Critical Care; D005745:Gastric Acidity Determination; D005753:Gastric Mucosa / Q000098:blood supply / Q000378:metabolism; D006635:Histamine H2 Antagonists / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010437:Peptic Ulcer / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control; D010438:Peptic Ulcer Hemorrhage / Q000517:prevention & control; D012306:Risk; D013315:Stress, Psychological / Q000150:complications* / Q000503:physiopathology
chemical_list: D000863:Antacids; D006635:Histamine H2 Antagonists