Influence of adrenergic antagonist and naloxone on the anti-allergic shock effect of electro-acupuncture in mice.
Our recent studies indicated that there was a good therapeutic effect selecting acupoints "Renzhong (Du26 =G.V. 26)" "Chengjiang (Ren. 24=C.V.24) of electro-acupuncture (E-A) in the treatment of allergic shock induced by bovine serum in mice. Phentolamine or propranolol injection before needling could partially reverse this anti-allergic shock effect, while practolol had no influence on the effect of E-A in the treatment. Another series of experiments showed that the E-A anti-allergic shock effect could not be blocked by Naloxone or previous exhaustion of pituitary endorphins, thus suggesting that there might be a difference between mechanisms underlying the analgesic effect and those underlying the anti-allergic shock effect of acupuncture.
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D015670:Acupuncture Therapy; D000707:Anaphylaxis / Q000628:therapy*; D000818:Animals; D004558:Electric Stimulation; D005260:Female; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009270:Naloxone / Q000494:pharmacology*; D010646:Phentolamine / Q000494:pharmacology*; D011217:Practolol / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology*
D009270:Naloxone; D011433:Propranolol; D011217:Practolol; D010646:Phentolamine