title: Human cerebellar cortex possesses high affinity binding sites for [3H]somatostatin.
abstract: Somatostatin binding sites have been identified in the human brain using [4-3H-(Phe6)]-somatostatin-14. In contrast to that of the rat, the human cerebellar cortex possesses a high density of somatostatin binding sites, comparable to that found in either the rat or human cerebral cortex. Autoradiographic localisation of somatostatin binding sites in the human cerebellum reveals that the highest density is associated with the granule cell layer.
authors.forename: C A
authors.initials: CA
authors.lastname: Whitford
authors.forename: J M
authors.initials: JM
authors.lastname: Candy
authors.forename: C A
authors.initials: CA
authors.lastname: Bloxham
authors.forename: A E
authors.initials: AE
authors.lastname: Oakley
authors.forename: C R
authors.initials: CR
authors.lastname: Snell
mesh_terms: D000368:Aged; D001345:Autoradiography; D001665:Binding Sites; D002531:Cerebellum / Q000032:analysis*; D006801:Humans; D066298:In Vitro Techniques; D008875:Middle Aged; D011956:Receptors, Cell Surface / Q000032:analysis*; D017481:Receptors, Somatostatin; D013004:Somatostatin / Q000378:metabolism; D014316:Tritium
chemical_list: D011956:Receptors, Cell Surface; D017481:Receptors, Somatostatin; D014316:Tritium; D013004:Somatostatin