title: Muscle relaxants for out-patient procedures.
abstract: The requirements for muscle relaxation in out-patient anesthesia are: a short total relaxation enabling the induction of an endotracheal tube followed by a period of 15-20 minutes of clinical relaxation. Reversal should be spontaneous. The new short acting muscle relaxants vecuronium and atracurium enable such a procedure, provided small doses are used (0.045 mg/kg for vecuronium or 0.2 mg/kg for atracurium. These small doses require a longer waiting time before intubation is easily performed (5 min for vecuronium and 6 min for atracurium). Spontaneous reversal of these small doses is achieved within 20-30 minutes. Potentiation of the relaxation by inhalational agents is not recommended.
authors.forename: J F
authors.initials: JF
authors.lastname: Crul
mesh_terms: D000556:Ambulatory Surgical Procedures; D001279:Atracurium; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007546:Isoquinolines / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology; D009125:Muscle Relaxants, Central / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology; D010197:Pancuronium / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000494:pharmacology; D011229:Preanesthetic Medication; D014673:Vecuronium Bromide
chemical_list: D007546:Isoquinolines; D009125:Muscle Relaxants, Central; D001279:Atracurium; D014673:Vecuronium Bromide; D010197:Pancuronium