Effect of prostaglandins PGE2 and PGF alpha 2 on the mean plaque size of bovine herpesvirus 1.
The effect of prostaglandins PGE2 and PGF alpha 2 on infectious bovine rhinotracheitis (IBR) virus (bovine herpesvirus 1; BHV-1) was studied by using the measurement of the mean size of plaques produced in cell culture by IBR/Cu5 strain. Three concentrations (0.1, 1 and 10 micrograms/ml) of prostaglandins, PGE2 and PGF alpha 2 were used. Each prostaglandin provoked an increase in the mean plaque size when compared to control plaques, at the concentrations 1 and 10 micrograms/ml for PGE2 and 10 micrograms/ml for PGF alpha 2.
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Service de Virologie, Immunologie et Pathologie des maladies virales, Faculté de Médecine Vétérinaire, Université de Liège, Bruxelles, Belgique.
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Thalasso
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Pastoret
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D002478:Cells, Cultured; D015237:Dinoprost / Q000494:pharmacology*; D015232:Dinoprostone / Q000494:pharmacology*; D007242:Herpesvirus 1, Bovine / Q000187:drug effects* / Q000254:growth & development; D066298:In Vitro Techniques; D010948:Viral Plaque Assay; D014776:Virus Cultivation
D015237:Dinoprost; D015232:Dinoprostone