[Participation of the opioid-ergic system in the regulation of afferent reactions of the damaged myocardium].
It has been established that in lesion of the myocardium accumulation of huge amount of algesic compounds may cause limitation of the level of cardiac afferentation. Use of naloxone, buterfanol tartrate and D-ala-2-lei-enkephalin prevent the development of the reaction. The possibility of participation of the endogenic cardiac opioids in anti-nociceptive reactions of heart during its lesion is considered.
Bilibin
D P
DP
Shevelev
O A
OA
Dzhaĭnendra Upadkhiaĭ
D000818:Animals; D001920:Bradykinin / Q000494:pharmacology; D002077:Butorphanol / Q000494:pharmacology; D002415:Cats; D004562:Electrocardiography; D004723:Endorphins / Q000502:physiology*; D004743:Enkephalin, Leucine / Q000031:analogs & derivatives / Q000494:pharmacology; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives*; D006321:Heart / Q000187:drug effects; D006329:Heart Conduction System / Q000187:drug effects / Q000503:physiopathology*; D009203:Myocardial Infarction / Q000503:physiopathology*; D009270:Naloxone / Q000494:pharmacology; D009475:Neurons, Afferent / Q000502:physiology; D011957:Receptors, Opioid / Q000502:physiology*
D004723:Endorphins; D011957:Receptors, Opioid; D009270:Naloxone; D004743:Enkephalin, Leucine; D016308:Enkephalin, Leucine-2-Alanine; D002077:Butorphanol; D001920:Bradykinin; C040996:enkephalin-Leu, Ala(2)-Arg(6)-
Uchastie opioidergicheskoĭ sistemy v reguliatsii afferentnykh reaktsiĭ povrezhdennogo miokarda.