title: Crohn's disease with persistence of Clostridium difficile, surgical elimination.
abstract: Clostridium difficile has been associated with increased activity of Crohn's disease in some patients, and in them its eradication has proved beneficial. We have seen a patient unresponsive to two courses of vancomycin with persistence of C. difficile colonization and toxin production in whom surgical intervention eliminated the C. difficile cytotoxin and organism.
authors.forename: P H
authors.initials: PH
authors.lastname: DeRidder
authors.forename: O
authors.initials: O
authors.lastname: Kadro
mesh_terms: D000293:Adolescent; D003013:Clostridium / Q000187:drug effects; D003424:Crohn Disease / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery*; D003603:Cytotoxins / Q000096:biosynthesis; D004352:Drug Resistance, Microbial; D006801:Humans; D008297:Male; D011241:Prednisone / Q000494:pharmacology / Q000627:therapeutic use; D012460:Sulfasalazine / Q000494:pharmacology / Q000627:therapeutic use; D014640:Vancomycin / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D003603:Cytotoxins; D012460:Sulfasalazine; D014640:Vancomycin; D011241:Prednisone