title: Tardive dyskinesia: developmental factors.
abstract: Tardive dyskinesia (TD) is an involuntary movement disorder predominantly the result of long-term neuroleptic administration. Several factors have been studied with conflicting results. In this paper, the authors compare a group of 17 TD patients with 17 non-TD controls to delineate possible etiological factors in the development of this syndrome. Factors like total neuroleptic and antiparkinsonian medication intake and organicity were not different in the groups. Only drug-free periods in the past history of TD patients were found to be statistically more significant (P less than 0.025) in these patients than in non-TD controls.
authors.forename: R
authors.initials: R
authors.lastname: Yassa
authors.forename: A M
authors.initials: AM
authors.lastname: Ghadirian
authors.forename: G
authors.initials: G
authors.lastname: Schwartz
mesh_terms: D000928:Antidepressive Agents / Q000494:pharmacology; D000978:Antiparkinson Agents / Q000494:pharmacology; D014150:Antipsychotic Agents / Q000008:administration & dosage* / Q000494:pharmacology; D004409:Dyskinesia, Drug-Induced / Q000209:etiology*; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D000928:Antidepressive Agents; D000978:Antiparkinson Agents; D014150:Antipsychotic Agents