title: Pharmacology of opioids. Part 2. Clinical aspects.
authors.forename: L E
authors.initials: LE
authors.lastname: Mather
authors.forename: M J
authors.initials: MJ
authors.lastname: Cousins
mesh_terms: D000284:Administration, Oral; D000367:Age Factors; D000701:Analgesics, Opioid / Q000009:adverse effects / Q000097:blood / Q000378:metabolism* / Q000494:pharmacology / Q000627:therapeutic use; D001775:Blood Circulation / Q000187:drug effects; D004347:Drug Interactions; D006207:Half-Life; D003932:Heroin / Q000378:metabolism; D006801:Humans; D007263:Infusions, Parenteral; D007267:Injections; D007273:Injections, Intramuscular; D007278:Injections, Spinal; D007422:Intestines / Q000187:drug effects; D007700:Kinetics; D008099:Liver / Q000187:drug effects; D008657:Metabolic Clearance Rate; D009020:Morphine / Q000378:metabolism; D010146:Pain / Q000188:drug therapy / Q000503:physiopathology; D010148:Intractable Pain / Q000188:drug therapy; D012119:Respiration / Q000187:drug effects
chemical_list: D000701:Analgesics, Opioid; D003932:Heroin; D009020:Morphine