title: Glucose tolerance in north Indians taking a high fibre diet.
abstract: In 249 individuals of different age groups, taking a high fibre diet naturally, glucose tolerance studies were done after a standard glucose load (1.73 g/kg body weight or 100 g glucose). A group of 156 of the subjects were also studied after a standardized hospital meal (258 g carbohydrate, 14 g fat, 47 g protein and 32 g fibre). Mean blood glucose values after the high fibre mixed meal were lower than after the glucose load. The mean 2-h postprandial blood glucose was 2-4 mmol/l lower compared to that observed in other studies using less carbohydrate. The postprandial blood glucose pattern is likely to be as a result of (a) the large amount of carbohydrate and fibre in the test meal (b) the fat and protein content of the test meal (c) the habitual intake of such a meal and (d) the nature and type of fibre consumed in the meal. Among the subjects 1.2 per cent were found to have non-insulin dependent diabetes mellitus while 2 per cent had impaired glucose tolerance. This prevalence of non-insulin dependent diabetes mellitus in subjects, who came predominantly from a rural or semi-rural background, is lower than that found in urban areas of Northern India. The effect of age on glucose tolerance was clearly seen after the glucose load (0.4 mol/l/decade) and after the mixed meal (0.1 mmol/l/decade). These findings suggest the potential of the constituents of a typical North Indian diet in improving glucose tolerance.
authors.affiliation: University Department of Medicine, Manchester Royal Infirmary, UK.
authors.forename: D
authors.initials: D
authors.lastname: Bhatnagar
mesh_terms: D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood; D004032:Diet; D004043:Dietary Fiber / Q000008:administration & dosage*; D004435:Eating; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D007194:India; D008297:Male; D008875:Middle Aged
chemical_list: D001786:Blood Glucose; D004043:Dietary Fiber