title: Linitis plastica of the esophagus.
abstract: A 62-yr-old woman was evaluated for a 2-wk history of regurgitation and weight loss. Radiologic studies demonstrated a stenotic region in the distal third of the esophagus. Multiple endoscopic biopsies were nondiagnostic. Esophagectomy and esophagogastrostomy revealed a diffusely infiltrating adenocarcinoma ("linitis plastica") of the distal esophagus, sparing the gastroesophageal junction and stomach. Despite the absence of metastatic disease at laparotomy, the patient developed metastases unresponsive to chemotherapy. The pathologic, radiographic, and endoscopic findings are consistent with primary linitis plastica of the esophagus.
authors.affiliation: Department of Medicine, Harper Hospital, Wayne State University, Detroit, Michigan 48201.
authors.forename: R
authors.initials: R
authors.lastname: Pazdur
authors.forename: T
authors.initials: T
authors.lastname: Olencki
authors.forename: G E
authors.initials: GE
authors.lastname: Herman
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology; D002293:Adenocarcinoma, Scirrhous / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D004947:Esophagus / Q000473:pathology*; D005260:Female; D006801:Humans; D008039:Linitis Plastica / Q000000981:diagnostic imaging / Q000473:pathology*; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011859:Radiography