title: [Toxicity and narcotic effect of sodium oxybutyrate and ketalar at different periods of combined radiation lesion, burn injury and irradiation exposure].
abstract: It has been shown that there are differences in the action of sodium hydroxybutyrate and ketamine depending on the stage and type of exposure. Alterations in the duration of anesthesia within the first four days after ionizing radiation are directly opposite to those seen under the conditions of the combined radiation-thermal injury (CRTI) and isolated burn trauma. The anesthetic action of ketamine is potentiated under the conditions of CRTI and remains unchanged under isolated exposures, whereas the toxicity, on the contrary, increases on the 30th day after burn and irradiation.
authors.forename: T Iu
authors.initials: TIu
authors.lastname: Il'iuchenok
authors.forename: B K
authors.initials: BK
authors.lastname: Rasulev
authors.forename: L A
authors.initials: LA
authors.lastname: Moiseeva
mesh_terms: D000701:Analgesics, Opioid; D000818:Animals; D001273:Atmosphere Exposure Chambers; D002056:Burns / Q000503:physiopathology*; D005720:Gamma Rays / Q000009:adverse effects; D006885:Hydroxybutyrates / Q000633:toxicity*; D000860:Hypoxia / Q000503:physiopathology; D007649:Ketamine / Q000633:toxicity*; D007928:Lethal Dose 50; D051379:Mice; D011833:Radiation Injuries, Experimental / Q000503:physiopathology*; D012978:Sodium Oxybate / Q000633:toxicity*; D013997:Time Factors
chemical_list: D000701:Analgesics, Opioid; D006885:Hydroxybutyrates; D007649:Ketamine; D012978:Sodium Oxybate
vernacular_title: Toksichnost' i narkoticheskiĭ éffekt natriia oksibutirata i ketalara v raznye periody kombinirovannogo radiatsionnogo porazheniia, ozhogovoĭ travmy i luchevogo vozdeĭstviia.