Cutaneous extravascular necrotizing granuloma in a patient with Takayasu's aortitis.
Cutaneous extravascular necrotizing granulomas (Churg-Strauss granulomas) have been noted in several systemic diseases, most often those producing or associated with systemic vasculitis. A young man with the clinical and histopathologic features of Takayasu's aortitis developed typical extravascular necrotizing granulomas of the skin. Takayasu's aortitis, like allergic granulomatosis and Wegener's granulomatosis, is a granulomatous vasculitis syndrome associated with the cutaneous Churg-Strauss granuloma.
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D000328:Adult; D001015:Aortic Arch Syndromes / Q000150:complications*; D006099:Granuloma / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D009336:Necrosis; D012867:Skin / Q000473:pathology*; D012871:Skin Diseases / Q000150:complications* / Q000473:pathology; D013625:Takayasu Arteritis / Q000150:complications*; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000150:complications* / Q000473:pathology