title: Neurogenic urethra: clinical relevance of isolated neuropathic dysfunction of the urethra, and the denervation supersensitivity of the urethra revisited.
abstract: Our clinical experience on isolated neuropathic dysfunction of the urethra is presented. By discussing the urodynamic findings in neurogenic urethra, wherein the denervation supersensitivity to alpha-adrenergic stimulation in the absence of vesical denervation was a common denominator, some insight into the modern concept of motor innervation of the urethra was attempted. Our data are supportive of the current dogma implicating a significant sympathetic contribution to both autonomic and somatomotor innervation of the urethra.
authors.affiliation: Department of Urology, Hokkaido University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Koyanagi
authors.forename: H
authors.initials: H
authors.lastname: Morita
authors.forename: K
authors.initials: K
authors.lastname: Taniguchi
authors.forename: M
authors.initials: M
authors.lastname: Kubota
authors.forename: Y
authors.initials: Y
authors.lastname: Shinno
authors.forename: T
authors.initials: T
authors.lastname: Takamatsu
mesh_terms: D000328:Adult; D000368:Aged; D003714:Denervation; D004576:Electromyography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology; D011942:Receptors, Adrenergic, alpha / Q000502:physiology; D013564:Sympathetic Nervous System / Q000503:physiopathology*; D014521:Urethra / Q000294:innervation*; D014522:Urethral Diseases / Q000503:physiopathology*; D001750:Urinary Bladder, Neurogenic / Q000503:physiopathology; D014554:Urination; D014563:Urodynamics
chemical_list: D011942:Receptors, Adrenergic, alpha