Solvent selectivity in the resolution of some regioisomeric and diastereomeric prostaglandin intermediates on silica.
The possibilities of predicting the selectivity in the resolution of regioisomeric and diastereomeric prostaglandin intermediates on silica gel was investigated. A satisfactory correlation between log alpha and the solvent localization parameters m and m0 was obtained, confirming the importance of solvent-solute localization in determining alpha values. The results will be useful in developing further the theory of the selectivity of resolution.
Lõhmus
M
M
Estonian Academy of Sciences, Tallinn, U.S.S.R.
Kirjanen
I
I
Lopp
M
M
Lille
U
U
D055598:Chemical Phenomena; D002627:Chemistry, Physical; D011453:Prostaglandins / Q000302:isolation & purification*; D012822:Silicon Dioxide; D012997:Solvents; D013056:Spectrophotometry, Ultraviolet; D013237:Stereoisomerism
D011453:Prostaglandins; D012997:Solvents; D012822:Silicon Dioxide