The molecular basis of second messenger systems for regulation of smooth muscle contractility.
Smooth muscle contractility is regulated by the intracellular signals calcium, cAMP and cGMP. The possible mechanisms for generating these signals, the intracellular receptors for these signals, and their potential intracellular targets are discussed briefly.
Hofmann
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Medizinische Fakultät, Universität des Saarlandes, Homburg-Saar, Federal Republic of Germany.
D000818:Animals; D002118:Calcium / Q000378:metabolism; D002147:Calmodulin / Q000378:metabolism; D000242:Cyclic AMP / Q000378:metabolism; D006152:Cyclic GMP / Q000378:metabolism; D006801:Humans; D009119:Muscle Contraction / Q000502:physiology; D009126:Muscle Relaxation / Q000502:physiology; D009130:Muscle, Smooth / Q000502:physiology*; D015290:Second Messenger Systems / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology
D002147:Calmodulin; D000242:Cyclic AMP; D006152:Cyclic GMP; D002118:Calcium