Gastric acid secretion in the toad Bufo marinus with the description of a new technique for in vivo monitoring.
A technique for the implantation of a pH electrode into the stomach of the toad, Bufo marinus, is described. The technique permits continuous monitoring of gastric pH for extended periods. Results from continuous monitoring and from acute measurements of gastric pH are compared in fasting and fed toads. Prostaglandin E, given orally with food, caused a dose-related delay in the fall of gastric pH which followed feeding.
Taylor
P M
PM
Tyler
M J
MJ
Shearman
D J
DJ
D000818:Animals; D002024:Bufo marinus; D015232:Dinoprostone; D004435:Eating; D005215:Fasting; D005744:Gastric Acid / Q000187:drug effects / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D016595:Misoprostol; D011458:Prostaglandins E / Q000494:pharmacology; D011459:Prostaglandins E, Synthetic / Q000494:pharmacology
D011458:Prostaglandins E; D011459:Prostaglandins E, Synthetic; D016595:Misoprostol; D015232:Dinoprostone