Bupropion in the long-term treatment of cyclic mood disorders: mood stabilizing effects.
The effects of bupropion HCl in treating 11 patients with bipolar or schizoaffective disorder were examined in an open trial. Most patients had been intolerant of or showed minimal to moderate improvement on lithium, neuroleptics, antidepressants, or a combination of these drugs. All patients were maintained on bupropion alone or bupropion in combination with low-dose neuroleptics or anxiolytics for 1 year or more, with little or no relapse and few side effects.
Wright
G
G
Galloway
L
L
Kim
J
J
Dalton
M
M
Miller
L
L
Stern
W
W
D000328:Adult; D000928:Antidepressive Agents / Q000627:therapeutic use*; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000523:psychology; D001835:Body Weight; D016642:Bupropion; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D004359:Drug Therapy, Combination; D004644:Emotions / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011427:Propiophenones / Q000627:therapeutic use*; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000188:drug therapy / Q000523:psychology; D013997:Time Factors
D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D011427:Propiophenones; D016642:Bupropion