Chromosomal localization of the human Thy-1 gene.
We have isolated the gene coding for human Thy-1. Introduction of this gene into HeLa cells by DNA-mediated transfer results in the expression of Thy-1 antigen on the cell surface. Chromosomal mapping of the Thy-1 gene by hybridization to metaphase chromosomes and Southern blots of DNA from hybrid cells indicate that the Thy-1 gene is located on the long arm of chromosome 11.
van Rijs
J
J
Giguère
V
V
Hurst
J
J
van Agthoven
T
T
Geurts van Kessel
A
A
Goyert
S
S
Grosveld
F
F
D000954:Antigens, Surface / Q000235:genetics*; D002906:Chromosomes, Human, 6-12 and X; D003001:Cloning, Molecular; D005786:Gene Expression Regulation; D005796:Genes; D006367:HeLa Cells; D006801:Humans; D009693:Nucleic Acid Hybridization; D018800:Thy-1 Antigens
D000954:Antigens, Surface; D018800:Thy-1 Antigens