title: [cAMP-dependent phosphorylation inhibits potential-dependent passive transport of Ca2+ in myometrial sarcolemma vesicles].
abstract: It is established that Ca2+ transport from the predominantly inverted vesicles of pig myometrium sarcolemma depends on the value of the membrane potential which is created on vesicles by the K+-valinomycin system. It is shown that variations in the membrane potential from -60 to +30 mV cause acceleration of the calcium transport from the vesicles, the maximal transport being observed at delta psi from 0 up to +30 mV. The endogenic and exogenic cAMP-dependent phosphorylation of plasma membrane proteins inhibits the passive transport of calcium at all the membrane potential values studied. A degree of potential-dependent Ca2+ transport inhibition correlates with the value of cAMP-dependent phosphorylation of sarcolemma proteins.
authors.forename: M D
authors.initials: MD
authors.lastname: Kurskiĭ
authors.forename: L G
authors.initials: LG
authors.lastname: Babich
authors.forename: T P
authors.initials: TP
authors.lastname: Kondratiuk
authors.forename: S F
authors.initials: SF
authors.lastname: Bychenok
mesh_terms: D000818:Animals; D001692:Biological Transport; D002118:Calcium / Q000378:metabolism*; D000242:Cyclic AMP / Q000502:physiology*; D005260:Female; D005456:Fluorescent Dyes; D007700:Kinetics; D008564:Membrane Potentials; D009215:Myometrium / Q000378:metabolism*; D010766:Phosphorylation; D012508:Sarcolemma / Q000378:metabolism*; D013552:Swine
chemical_list: D005456:Fluorescent Dyes; D000242:Cyclic AMP; D002118:Calcium
vernacular_title: tsAMP-zavisimoe fosforilirovanie ingibiruet potentsialzavisimyĭ passivnyĭ transport Ca2+ v vezikulalk sarkolemmy miometriia.