T-lymphocyte subpopulations in multiple sclerosis--do they help to judge immunosuppressive therapy?
T-cell subpopulations were tested in multiple sclerosis (MS) patients before and after cyclophosphamide (n = 38) and corticotropin (n = 37) treatment and physiotherapy (n = 30). There were no specific changes of subset ratios immediately after immunosuppressive treatment. However, T-cell subpopulations showed great day-to-day variations in MS patients.
Henneberg
A
A
Department Neurology, University of Ulm, Federal Republic of Germany.
Fischer
E G
EG
Kornhuber
H H
HH
D000324:Adrenocorticotropic Hormone / Q000627:therapeutic use; D000911:Antibodies, Monoclonal; D003520:Cyclophosphamide / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007958:Leukocyte Count; D009103:Multiple Sclerosis / Q000188:drug therapy / Q000276:immunology*; D013601:T-Lymphocytes / Q000145:classification / Q000276:immunology*
D000911:Antibodies, Monoclonal; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D000324:Adrenocorticotropic Hormone