title: Scanning independent ribosomal initiation of the Sendai virus X protein.
abstract: Both peptide antisera and monoclonal antibodies detect a 10-kd protein (X) in Sendai virus infected cells, which represents approximately the last 95 residues of the 568-amino-acid-long P protein. The X protein does not appear to be derived from a precursor P in vivo, and in in vitro X can be made under conditions in which P synthesis has been arrested by hybridized DNA fragments or specific cleavage of the mRNA. X initiation is nevertheless cap dependent. Ribosomes which initiate X appear to pass directly from the cap to the initiation codon.
authors.affiliation: Department of Microbiology, University of Geneva Medical School, Switzerland.
authors.forename: J
authors.initials: J
authors.lastname: Curran
authors.forename: D
authors.initials: D
authors.lastname: Kolakofsky
mesh_terms: D000818:Animals; D002460:Cell Line; D015151:Immunoblotting; D010222:Parainfluenza Virus 1, Human / Q000235:genetics* / Q000378:metabolism; D010750:Phosphoproteins / Q000096:biosynthesis / Q000235:genetics; D011233:Precipitin Tests; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D012270:Ribosomes / Q000378:metabolism*; D014764:Viral Proteins / Q000096:biosynthesis* / Q000235:genetics
chemical_list: C055859:P protein, Sendai virus; D010750:Phosphoproteins; D012333:RNA, Messenger; D014764:Viral Proteins