True cryptorchidism and retractile testes in infertile men.
The present study entails clinical evaluation of 77 infertile men with testicular descent disturbances. The results summarize as follows: The incidence of disturbance in testicular descent among infertile men was 15.5%, 15.5% and 4.9% in azoo-, oligozoo- (less than or equal to 10 mill/ml) and normozoo- (greater than 10 mill/ml) spermia, respectively. Out of the 77 men investigated, 50 had a history of true cryptorchidism and 27 retractile testes. 31 of the patients with cryptorchidism had previously been subjected to orchidopexy. In the group of infertile men with a history of retractile testes, 20 subjects still retained palpable pathological changes of the testes. Testicular biopsies (from men with retractile testes and sperm count below 10 mill/ml) demonstrated hypospermatogenesis (germ cell arrest to aplasia). 6) 53% of the subjects exhibited elevated serum FSH. Two men had developed testis tumours (seminoma/teratoma). It is advocated that early hormonal therapy and/or surgical procedures should be initiated in an attempt to improve the chances of future fertility both in cryptorchidism and retractile testes.
Abyholm
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Oian
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Gordeladze
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JO
D000328:Adult; D003456:Cryptorchidism / Q000150:complications* / Q000601:surgery; D004407:Dysgerminoma / Q000209:etiology; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007248:Infertility, Male / Q000209:etiology*; D008297:Male; D009845:Oligospermia / Q000209:etiology; D013076:Sperm Count; D013091:Spermatogenesis; D013724:Teratoma / Q000209:etiology; D013736:Testicular Neoplasms / Q000209:etiology
D005640:Follicle Stimulating Hormone