title: A comparative study of serum proteins ability to scavenge active oxygen species: O2-. and OCl-.
abstract: The ability of serum proteins (albumin, immunoglobulin G) and protein antioxidants (ceruloplasmin, superoxide dismutase and transferrin) to react with O2-. and OCl-, was studied. The interaction between serum proteins and OCl- was shown to be non-specific. Ceruloplasmin is the most effective OCl- trapping protein, and it reacts with O2-. with a considerable efficiency. Therefore, ceruloplasmin is supposed to be the main scavenger of toxic oxygen species generated by stimulated neutrophils.
authors.affiliation: Department of Biochemistry, Leningrad State University, USSR.
authors.forename: B P
authors.initials: BP
authors.lastname: Sharonov
authors.lastname: Govorova NJu
authors.forename: S N
authors.initials: SN
authors.lastname: Lyzlova
mesh_terms: D001798:Blood Proteins / Q000502:physiology*; D002570:Ceruloplasmin / Q000502:physiology; D006997:Hypochlorous Acid / Q000378:metabolism*; D007074:Immunoglobulin G / Q000502:physiology; D008163:Luminescent Measurements; D010586:Phagocytes / Q000502:physiology; D012709:Serum Albumin / Q000502:physiology; D013482:Superoxide Dismutase / Q000502:physiology; D013481:Superoxides / Q000378:metabolism*; D014168:Transferrin / Q000502:physiology
chemical_list: D001798:Blood Proteins; D007074:Immunoglobulin G; D012709:Serum Albumin; D014168:Transferrin; D013481:Superoxides; D006997:Hypochlorous Acid; D013482:Superoxide Dismutase; D002570:Ceruloplasmin