Autonomic nervous system activity in Macaca fascicularis.
This study was performed to determine the contributions of the sympathetic and parasympathetic nervous systems to cardiovascular control. Hexamethonium was administered to block the autonomic ganglia, propranolol to block beta adrenergic receptors of the sympathetic nervous system, and methylatropine to block the parasympathetic nervous system. The results of this study indicate high sympathetic tone and low parasympathetic tone in resting Macaca fascicularis. These findings are different from those in man but are similar to other nonhuman primates.
Hartley
L H
LH
Rodger
R F
RF
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D001286:Atropine Derivatives / Q000494:pharmacology; D001341:Autonomic Nervous System / Q000502:physiology*; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D018738:Hexamethonium; D006584:Hexamethonium Compounds / Q000494:pharmacology; D008251:Macaca / Q000502:physiology*; D008252:Macaca fascicularis / Q000502:physiology*; D008297:Male; D011433:Propranolol / Q000494:pharmacology
D001286:Atropine Derivatives; D006584:Hexamethonium Compounds; D018738:Hexamethonium; D001285:Atropine; C006649:methylatropine; D011433:Propranolol