title: Acinetobacter bacteriocin typing.
abstract: A technique for typing Acinetobacter sp. by bacteriocin production has been developed. One hundred and seventy-six cultures from patients in outbreaks, in the community and environmental sources were identified, tested for sensitivity to gentamicin and bacteriocin typed; 154 were A. anitratus and the remainder A.lwoffi. Only one A.lwoffi strain produced bacteriocin. Ten of 22 were sensitive to bacteriocins and could be used as indicators. A close association was found between bacteriocin production and gentamicin resistance: MIC 4 mg/ml. Using six indicator strains 100/104 (96%) gentamicin-resistant strains were typed with nine distinct patterns of inhibition. Overall typability was 65% but 100/176 (56%) fell into only two groups. The technique may be of value in studying the epidemiology of Acinetobacter.
authors.forename: H J
authors.initials: HJ
authors.lastname: Andrews
mesh_terms: D000150:Acinetobacter / Q000145:classification* / Q000187:drug effects; D001430:Bacteriocins / Q000096:biosynthesis / Q000494:pharmacology; D001434:Bacteriophage Typing / Q000379:methods; D003428:Cross Infection / Q000382:microbiology; D004352:Drug Resistance, Microbial; D004783:Environmental Microbiology; D005839:Gentamicins / Q000494:pharmacology; D006757:Hospital Units; D006801:Humans; D008826:Microbial Sensitivity Tests; D014357:Trypsin / Q000494:pharmacology
chemical_list: D001430:Bacteriocins; D005839:Gentamicins; D014357:Trypsin