title: [Effect of astemizole on psychophysical performance].
abstract: Within four partial clinical trials of Astemizole versus placebo it has been proved, that no differences regarding the driving ability and the safe operation of machinery could be detected. Furthermore it could be observed, that there was no disadvantageous efficacy concerning subjective behaviour and that Astemizole did not potentiate Diazepam and alcohol.
authors.forename: L
authors.initials: L
authors.lastname: Moser
mesh_terms: D000428:Alcohol Drinking; D001143:Arousal / Q000187:drug effects; D016589:Astemizole; D001334:Automobile Driving; D001562:Benzimidazoles / Q000009:adverse effects*; D002986:Clinical Trials as Topic; D003975:Diazepam / Q000009:adverse effects; D004311:Double-Blind Method; D004357:Drug Synergism; D006634:Histamine H1 Antagonists / Q000009:adverse effects*; D006801:Humans; D007665:Ketotifen / Q000009:adverse effects; D011597:Psychomotor Performance / Q000187:drug effects*; D011930:Reaction Time / Q000187:drug effects
chemical_list: D001562:Benzimidazoles; D006634:Histamine H1 Antagonists; D016589:Astemizole; D003975:Diazepam; D007665:Ketotifen
vernacular_title: Die Wirkung von Astemizol auf die psychophysischen Leistungen.