Amino acid transport by corneal epithelial cells from the toad, Bufo marinus.
alpha-Aminoisobutyric acid is actively accumulated by the epithelium of the cornea of the toad, Bufo marinus, resulting in a tissue to medium ratio of 4 to 1 after 40 min of incubation. The accumulation of alpha-aminoisobutyric acid is ouabain-sensitive and dependent upon the presence of extracellular sodium. Transport is inhibited by carbon monoxide, 6-aminonicotinamide, arsenite and n-heptyl-3-hydroxy-quinoline-n-oxide and stimulated by diamide.
Cooperstein
D F
DF
D000621:Aminoisobutyric Acids / Q000378:metabolism*; D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D002024:Bufo marinus; D003315:Cornea / Q000378:metabolism*; D004848:Epithelium / Q000378:metabolism; D007700:Kinetics; D010042:Ouabain / Q000494:pharmacology
D000621:Aminoisobutyric Acids; C100049:2-aminoisobutyric acid; D010042:Ouabain