Disinfectant induced changes in the antibiotic sensitivity and phage typing pattern in Staphylococcus aureus.
Serial passage through disinfectants at sub-minimal inhibitory concentrations induced antibiotic resistances in 30.5% of the derived phenotypic variants of five strains of Staphylococcus aureus. A proportion of these phenotypic variants showed changes in their phage typing pattern by becoming susceptible to an increased number of phages, and a change from phage non-typable to typable was also observed. A loss of temperate phages was noted in some variants when subjected to reverse phage typing.
Sivaji
Y
Y
Mandal
A
A
Agarwal
D S
DS
D004202:Disinfectants / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D008826:Microbial Sensitivity Tests; D013204:Staphylococcus Phages / Q000502:physiology; D013211:Staphylococcus aureus / Q000145:classification / Q000187:drug effects*
D004202:Disinfectants