Nonfamilial intestinal polyposis and brain tumor in a 5-year-old girl.
A 5-year-old girl with glioblastoma multiforme and simultaneous adenocarcinoma in one of multiple colonic polyps is the youngest reported case of Turcot's syndrome. A literature survey and a classification based on family pedigree and pattern of inheritance are proposed.
Castello
M A
MA
1st Pediatric Department, Rome University, Italy.
Operamolla
P
P
Clerico
A
A
Taucci
M
M
Mazzoni
G
G
Gallo
P
P
Imperato
C
C
D000230:Adenocarcinoma / Q000235:genetics*; D000367:Age Factors; D001932:Brain Neoplasms / Q000235:genetics*; D002675:Child, Preschool; D003111:Colonic Polyps / Q000235:genetics*; D005260:Female; D005909:Glioblastoma / Q000235:genetics*; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000235:genetics*; D010859:Pigmentation Disorders / Q000150:complications / Q000235:genetics; D012004:Rectal Neoplasms / Q000235:genetics*; D013577:Syndrome