title: Vasoactive intestinal polypeptide-secreting ganglioneuromatosis affecting the entire colon and rectum.
abstract: This report describes a 7-year-old boy presenting with watery diarrhea, hypokalemia, and hypochlohydria associated with vasoactive intestinal polypeptide (VIP)-secreting ganglioneuromatosis involving the entire colon and rectum. The child's symptoms resolved following proctocolectomy, and the VIP levels returned to normal. Although 55 previous children have been reported with VIP-secreting tumors, this case is the first involving the entire colon and rectum.
authors.affiliation: Department of Surgery, Indiana University School of Medicine, Indianapolis.
authors.forename: F J
authors.initials: FJ
authors.lastname: Rescorla
authors.forename: D W
authors.initials: DW
authors.lastname: Vane
authors.forename: J F
authors.initials: JF
authors.lastname: Fitzgerald
authors.forename: K W
authors.initials: KW
authors.lastname: West
authors.forename: J L
authors.initials: JL
authors.lastname: Grosfeld
mesh_terms: D007516:Adenoma, Islet Cell / Q000209:etiology*; D002648:Child; D003110:Colonic Neoplasms / Q000378:metabolism*; D005729:Ganglioneuroma / Q000378:metabolism*; D006801:Humans; D008297:Male; D012004:Rectal Neoplasms / Q000378:metabolism*; D014660:Vasoactive Intestinal Peptide / Q000378:metabolism*; D003969:Vipoma / Q000209:etiology*
chemical_list: D014660:Vasoactive Intestinal Peptide