Spontaneous infection or vaccination as cause of acute disseminated encephalomyelitis.
This report describes an approach to determine which of 2 possible etiologies could be responsible for a disease, in this instance acute disseminated encephalomyelitis (ADEM). Information about latency periods was obtained from eighteen reference sources in the literature. Analysis of these data indicate that it would be 9-18 times more likely for ADEM to develop 5 days after a wild virus infection (measles, for example) than 28 days after a vaccination.
Murphy
J
J
Austin
J
J
D004679:Encephalomyelitis / Q000209:etiology*; D004673:Encephalomyelitis, Acute Disseminated / Q000209:etiology*; D006801:Humans; D007252:Influenza Vaccines / Q000009:adverse effects; D008875:Middle Aged; D011336:Probability; D011819:Rabies Vaccines / Q000009:adverse effects; D012141:Respiratory Tract Infections / Q000150:complications; D013997:Time Factors; D014777:Virus Diseases / Q000150:complications*
D007252:Influenza Vaccines; D011819:Rabies Vaccines