The mouse anococcygeus muscle as a preparation for the bioassay of oxytocin.
Oxytocin (0.1-10 nM) caused reproducible, dose-related contractions of the male mouse anococcygeus. Desensitization was not a major problem. The muscle was shown to be a useful oxytocin bioassay preparation, having a good index of precision (0.04).
Botting
J H
JH
Gibson
A
A
D000818:Animals; D001681:Biological Assay; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D009119:Muscle Contraction / Q000187:drug effects; D009132:Muscles / Q000187:drug effects*; D010121:Oxytocin / Q000494:pharmacology*
D010121:Oxytocin