Post-operative chemotherapy for ovarian carcinoma: a prospective study with cyclophosphamide.
Seventy consecutive patients with carcinoma of the ovary were managed in our unit by laparotomy and extensive debulking procedures over a period of 8 years. Intensive post-operative chemotherapy was given with intravenous cyclophosphamide. The mean follow-up period was 2.6 years. Our results showed that 19 patients with early disease (stages I and II) showed complete remission but seven subsequently died of recurrent disease. The others with more advanced disease showed little response to treatment.
Akinkugbe
A
A
Uguru
V E
VE
Mordi
V P
VP
D000293:Adolescent; D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000188:drug therapy* / Q000401:mortality / Q000601:surgery; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000601:surgery; D011182:Postoperative Care; D011446:Prospective Studies; D013997:Time Factors
D003520:Cyclophosphamide