Three case reports of acute paroxysmal excitement associated with alprazolam treatment.
Three patients receiving alprazolam developed, within days after beginning treatment, acute excitatory states with features more suggestive of mania than of disinhibition syndrome. The authors suggest a neurochemical link between mania and disinhibitory states.
Strahan
A
A
Rosenthal
J
J
Kaswan
M
M
Winston
A
A
D000208:Acute Disease; D000328:Adult; D017109:Akathisia, Drug-Induced; D000525:Alprazolam; D014151:Anti-Anxiety Agents / Q000009:adverse effects*; D001008:Anxiety Disorders / Q000188:drug therapy; D001569:Benzodiazepines / Q000009:adverse effects*; D001714:Bipolar Disorder / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008297:Male; D010200:Panic
D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D000525:Alprazolam