Actions of somatostatin on lipid metabolism in mouse cerebral cortex slices.
Cerebral cortex slices from mice were used to investigate the variations of lipid metabolism by somatostatin. Somatostatin decreased [14C]acetate incorporation into all lipid fractions significantly. Likewise, the peptide evoked a decrease of triglyceride lipase activity. The incorporation of [32P]orthophosphate into phospholipids was diminished by somatostatin. These results add more information about the effects of somatostatin in cerebral cortex.
Catalán
R E
RE
Martínez
A M
AM
Aragonés
M D
MD
Godoy
J E
JE
D000085:Acetates / Q000378:metabolism; D000818:Animals; D002540:Cerebral Cortex / Q000378:metabolism*; D066298:In Vitro Techniques; D008049:Lipase / Q000378:metabolism; D050356:Lipid Metabolism; D008297:Male; D051379:Mice; D010710:Phosphates / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism; D013004:Somatostatin / Q000494:pharmacology*
D000085:Acetates; D010710:Phosphates; D010743:Phospholipids; D013004:Somatostatin; D008049:Lipase