title: High-performance liquid chromatography systems for the separation of benzodiazepines and their metabolites.
abstract: The high-performance liquid chromatographic (HPLC) retention characteristics of 21 benzodiazepine drugs and some of their metabolites have been examined on both silica and ODS-silica packing materials. Four HPLC systems have been considered and retention data are presented for the drugs on these systems. The correlation of retention data on the systems is considered with reference to the problem of identifying unknown benzodiazepines.
authors.forename: R
authors.initials: R
authors.lastname: Gill
authors.forename: B
authors.initials: B
authors.lastname: Law
authors.forename: J P
authors.initials: JP
authors.lastname: Gibbs
mesh_terms: D014151:Anti-Anxiety Agents / Q000302:isolation & purification* / Q000378:metabolism; D001569:Benzodiazepines; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D005554:Forensic Medicine; D006801:Humans; D007202:Indicators and Reagents; D012822:Silicon Dioxide
chemical_list: D014151:Anti-Anxiety Agents; D007202:Indicators and Reagents; D001569:Benzodiazepines; D012822:Silicon Dioxide