Immunoprecipitation of Epstein-Barr virus (EBV)-specific proteins by prelymphomatous and normal baboon sera containing antibodies reactive with EBV early antigen.
Carbon (14C)-amino acid mixture-labelled antigen extracted from 12-0-tetradecanoyl-phorbol-13-acetate (TPA) and sodium n-butyrate-induced P3HR-1 cells was immunoprecipitated with sera from normal, prelymphomatous and lymphomatous baboons, as well as with sera from human controls. Most of the Epstein-Barr virus (EBV)-specific proteins that were precipitated by human sera were also precipitated by baboon sera. A major difference between prelymphomatous and normal control baboon sera was that 5 out of 6 the former and none of the latter immuno-precipitated an EBV-early antigen-specific protein with Mr 31,000.
Voevodin
A F
AF
Hirsch
I
I
D000818:Animals; D000918:Antibody Specificity; D000956:Antigens, Viral / Q000276:immunology*; D003429:Cross Reactions; D006564:Herpesviridae / Q000276:immunology; D006566:Herpesviridae Infections / Q000276:immunology / Q000662:veterinary*; D004854:Herpesvirus 4, Human / Q000276:immunology*; D008223:Lymphoma / Q000276:immunology / Q000662:veterinary*; D008992:Monkey Diseases / Q000276:immunology* / Q000382:microbiology; D010215:Papio / Q000276:immunology / Q000382:microbiology*; D014412:Tumor Virus Infections / Q000276:immunology / Q000662:veterinary*; D014764:Viral Proteins / Q000276:immunology*
D000956:Antigens, Viral; C033305:Epstein-Barr virus early antigen; D014764:Viral Proteins