Distribution of 67Ga-citrate in abscess-induced rat by quantitative whole body autoradiography.
Distribution of 67Ga-citrate in inflammatory tissues was determined, and correlation between the 67Ga-uptake and capillary permeability of plasma from blood vessels in the inflammatory tissue was elucidated, by quantitative whole body autoradiography and double tracer autoradiography. The distribution of 67Ga in inflammatory tissue was similar to that of 131I-HSA and 99mTc-HSA, which were applied as an index to the plasma element. These results showed that the capillary permeability of plasma from blood vessels in the inflammatory tissue increases, and this causes the 67Ga-uptake.
Sanada
S
S
School of Allied Medical Professions, Kanazawa University, Japan.
Ando
A
A
Hiraki
T
T
Hisada
K
K
Nitta
K
K
D000038:Abscess / Q000000981:diagnostic imaging / Q000378:metabolism*; D000818:Animals; D001345:Autoradiography; D002199:Capillary Permeability; D002951:Citrates / Q000493:pharmacokinetics*; D019343:Citric Acid; D008297:Male; D011877:Radionuclide Imaging; D051381:Rats; D011919:Rats, Inbred Strains; D014018:Tissue Distribution
D002951:Citrates; D019343:Citric Acid