Sedimentation analysis of the RNAs isolated from interfering particles of Lassa and Machupo viruses.
Vero cells chronically infected with Lassa virus as well as BHK-21 cells chronically infected with Machupo virus produced particles interfering with the replication of homologous, but not heterogeneous viruses. RNAs of standard virus particles contained 4 sedimentation classes of molecules: 28-31 S, 22-24S, 18 S and 4-6 S. The 28-31 S molecules were not present among the RNAs of interfering particles of Lassa and Machupo viruses.
Lukashevich
I S
IS
Trofimov
N M
NM
Golubev
V P
VP
Maryankova
R F
RF
D000818:Animals; D001116:Arenaviridae / Q000235:genetics*; D006477:Arenaviruses, New World / Q000235:genetics* / Q000502:physiology; D002460:Cell Line; D002522:Chlorocebus aethiops; D006224:Cricetinae; D007836:Lassa virus / Q000235:genetics* / Q000502:physiology; D012367:RNA, Viral / Q000032:analysis*; D014762:Viral Interference; D014771:Virion / Q000032:analysis / Q000235:genetics; D014779:Virus Replication
D012367:RNA, Viral