Uptake of hexoses and lipids into rabbit jejunum and colon following ileal resection: effect of variations in the cholesterol and fat content of the diet.
After 6 weeks feeding on either a high-cholesterol/fat (H) or a low-cholesterol/fat (L) diet, jejunal and colonic uptake was measured using a previously validated in vitro technique in control rabbits with an intact intestinal tract (C) and in animals submitted to the surgical removal of the distal half of the small intestine (R). The uptake of hexoses and fatty acids was influenced by ileal resection and by diet. Dietary manipulation altered the passive and active transport properties of the intestine and had a different effect on intestinal transport in animals with an ileal resection than in animals with an intact small intestine.
Thomson
A B
AB
Keelan
M
M
McIntyre
Y
Y
MacLeod
J
J
D000818:Animals; D002784:Cholesterol / Q000378:metabolism*; D002791:Cholesterol, Dietary / Q000494:pharmacology*; D003106:Colon / Q000187:drug effects / Q000378:metabolism*; D004041:Dietary Fats / Q000494:pharmacology*; D005230:Fatty Acids, Nonesterified / Q000378:metabolism*; D005233:Fatty Alcohols / Q000378:metabolism; D006601:Hexoses / Q000378:metabolism*; D007082:Ileum / Q000502:physiology*; D007408:Intestinal Absorption / Q000187:drug effects*; D007583:Jejunum / Q000187:drug effects / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D011817:Rabbits; D013329:Structure-Activity Relationship
D002791:Cholesterol, Dietary; D004041:Dietary Fats; D005230:Fatty Acids, Nonesterified; D005233:Fatty Alcohols; D006601:Hexoses; C029383:n-decyl alcohol; D002784:Cholesterol