title: Mode of action studies. Basis for the search of new antifungal drugs.
authors.affiliation: Department of Comparative Biochemistry, Janssen Research Foundation, Beerse, Belgium.
authors.forename: H
authors.initials: H
authors.lastname: Vanden Bossche
authors.forename: P
authors.initials: P
authors.lastname: Marichal
authors.forename: J
authors.initials: J
authors.lastname: Gorrens
authors.forename: H
authors.initials: H
authors.lastname: Geerts
authors.forename: P A
authors.initials: PA
authors.lastname: Janssen
mesh_terms: D000085:Acetates / Q000378:metabolism; D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects / Q000378:metabolism*; D002176:Candida albicans / Q000378:metabolism*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D015195:Drug Design; D004875:Ergosterol / Q000096:biosynthesis; D006863:Hydrogen-Ion Concentration; D017964:Itraconazole; D007654:Ketoconazole / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology*; D008861:Microsomes / Q000378:metabolism*
chemical_list: D000085:Acetates; D000935:Antifungal Agents; D017964:Itraconazole; D003577:Cytochrome P-450 Enzyme System; D007654:Ketoconazole; D004875:Ergosterol