title: [3H]imipramine binding sites are decreased in platelets of chronic pain patients.
abstract: Tritiated imipramine binding to whole platelets was measured in 16 chronic pain patients not suffering from major depression and in a control group. Maximum binding was significantly lower in chronic pain patients than in the control group, whereas the binding affinity was not significantly different.
authors.affiliation: Department of Psychiatry, University of Padua School of Medicine, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Magni
authors.forename: F
authors.initials: F
authors.lastname: Andreoli
authors.forename: C
authors.initials: C
authors.lastname: Arduino
authors.forename: D
authors.initials: D
authors.lastname: Arsié
authors.forename: F
authors.initials: F
authors.lastname: Ceccherelli
authors.forename: F
authors.initials: F
authors.lastname: Ambrosio
authors.forename: M
authors.initials: M
authors.lastname: Eandi
mesh_terms: D001792:Blood Platelets / Q000032:analysis*; D002352:Carrier Proteins; D002908:Chronic Disease; D003863:Depression / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000097:blood*; D011955:Receptors, Drug; D017981:Receptors, Neurotransmitter / Q000032:analysis*
chemical_list: D002352:Carrier Proteins; D011955:Receptors, Drug; D017981:Receptors, Neurotransmitter; C027775:imipramine receptor