title: The inhibitor protein of the cyclic AMP-dependent protein kinase-catalytic subunit interaction. Composition of multiple complexes.
abstract: It has been previously demonstrated that the combination of pure preparations of the inhibitor protein of the cyclic AMP-dependent protein kinase and the catalytic subunit of this enzyme resulted in the formation of multiple complexes [Van Patten, Fletcher & Walsh (1986) J. Biol. Chem. 261, 5514-5523]. In the present study it is demonstrated that these multiple species occur because the bovine heart protein kinase preparation contains multiple forms of catalytic subunit [Kinzel, Hotz, König, Gagelmann, Pyerin, Reed, Köbler, Hofmann, Obst, Gensheimer, Goldblatt & Shaltiel (1987) Arch. Biochem. Biophys. 253, 341-349].
authors.affiliation: Department of Biological Chemistry, School of Medicine, University of California, Davis 95616.
authors.forename: S M
authors.initials: SM
authors.lastname: Van Patten
authors.forename: A
authors.initials: A
authors.lastname: Hotz
authors.forename: V
authors.initials: V
authors.lastname: Kinzel
authors.forename: D A
authors.initials: DA
authors.lastname: Walsh
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D001667:Binding, Competitive; D002352:Carrier Proteins / Q000378:metabolism*; D002384:Catalysis; D002417:Cattle; D000242:Cyclic AMP / Q000378:metabolism*; D047908:Intracellular Signaling Peptides and Proteins; D047428:Protein Kinase Inhibitors
chemical_list: D002352:Carrier Proteins; D047908:Intracellular Signaling Peptides and Proteins; D047428:Protein Kinase Inhibitors; C015482:protein kinase modulator; D000255:Adenosine Triphosphate; D000242:Cyclic AMP