Pituitary growth hormone and hypothalamic somatostatin in young female rats versus old constant estrous female rats.
Pituitary content and concentration of growth hormone was significantly reduced, and hypothalamic somatostatin content significantly increased, in old constant estrous as compared to young female rats. Increased levels of somatostatin may contribute to the decrease in pituitary growth hormone levels in these animals.
Forman
L J
LJ
Sonntag
W E
WE
Hylka
V W
VW
Meites
J
J
D000375:Aging; D000818:Animals; D004971:Estrus; D005260:Female; D013006:Growth Hormone / Q000378:metabolism*; D007031:Hypothalamus / Q000378:metabolism*; D010902:Pituitary Gland / Q000378:metabolism*; D011247:Pregnancy; D051381:Rats; D013004:Somatostatin / Q000378:metabolism*
D013004:Somatostatin; D013006:Growth Hormone