title: Complete complementary DNA of rat tyrosine aminotransferase messenger RNA. Deduction of the primary structure of the enzyme.
abstract: The primary structure of rat tyrosine aminotransferase (L-tyrosine:2-oxoglutarate aminotransferase; EC 2.6.1.5), a liver-specific enzyme involved in gluconeogenesis, has been deduced from the nucleotide sequence of a cloned full-length cDNA. The mRNA is 2362 nucleotides long (excluding the poly(A) tail) and codes for a polypeptide of 454 amino acids with a molecular weight of 50634. Unambiguous identification was obtained by comparison of this sequence with the amino acid sequences of several peptides obtained from the purified enzyme.
authors.forename: T
authors.initials: T
authors.lastname: Grange
authors.forename: C
authors.initials: C
authors.lastname: Guénet
authors.forename: J B
authors.initials: JB
authors.lastname: Dietrich
authors.forename: S
authors.initials: S
authors.lastname: Chasserot
authors.forename: M
authors.initials: M
authors.lastname: Fromont
authors.forename: N
authors.initials: N
authors.lastname: Befort
authors.forename: J
authors.initials: J
authors.lastname: Jami
authors.forename: G
authors.initials: G
authors.lastname: Beck
authors.forename: R
authors.initials: R
authors.lastname: Pictet
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics*; D051381:Rats; D014444:Tyrosine Transaminase / Q000235:genetics*
chemical_list: D012333:RNA, Messenger; D004247:DNA; D014444:Tyrosine Transaminase