Cell mediated immune response following foot-and-mouth disease vaccination in buffalo calves.
The cell mediated immune (CMI) response was studied by E-rosette formation in vitro and delayed type hypersensitivity (DTH) skin reaction in buffalo calves vaccinated with monovalent type 0 as well as with a polyvalent foot-and-mouth disease vaccine. Up to 35 days post-vaccination there was a significant increase (P less than 0.05) in the number of T-lymphocytes in both animal groups. Thereafter, the number of lymphocytes decreased. Delayed type hypersensitivity (DTH) skin reaction was characterized by a significant increase in skin thickness; histology showed mononuclear infiltration and perivascular cuffing.
Sharma
R
R
Prasad
S
S
Ahuja
K L
KL
Rahman
M M
MM
Kumar
A
A
D000818:Animals; D005537:Aphthovirus / Q000276:immunology*; D002020:Buffaloes; D005536:Foot-and-Mouth Disease / Q000276:immunology; D006968:Hypersensitivity, Delayed / Q000662:veterinary; D007111:Immunity, Cellular; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*; D014611:Vaccination / Q000662:veterinary; D014765:Viral Vaccines / Q000276:immunology*
D014765:Viral Vaccines