title: [Hypophyseal-gonadal and hypophyseal-corticoadrenal system in healthy persons and in patients with ischemic heart disease aged 60-89 years].
abstract: Serum basal concentrations of testosterone, estradiol, and androstenedione, FSH, LH, prolactin, ACTH and cortisol were studied in healthy persons, CHD patients aged 60-89, and in healthy persons aged 20-35 (controls). In some persons of each group a study was made of changes in the concentration of blood prolactin. ACTH, cortisol and urinary excretion of free cortisol as a result of bicycle ergometry exercise testing (submaximum in healthy persons and threshold in patients). A conclusion was made that "endocrinological age" of these hormonal systems in CHD patients aged 60-89 was older than in healthy persons of similar age, and hormonal imbalance continued to be a risk factor at late stages of life.
authors.forename: A N
authors.initials: AN
authors.lastname: Kovalenko
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000097:blood; D000368:Aged; D000369:Aged, 80 and over; D000735:Androstenedione / Q000097:blood; D003327:Coronary Disease / Q000097:blood / Q000503:physiopathology*; D004958:Estradiol / Q000097:blood; D005080:Exercise Test; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006062:Gonadotropins / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000652:urine; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008875:Middle Aged; D010902:Pituitary Gland / Q000502:physiology / Q000503:physiopathology*; D010913:Pituitary-Adrenal System / Q000502:physiology / Q000503:physiopathology*; D011388:Prolactin / Q000097:blood; D012307:Risk Factors; D013739:Testosterone / Q000097:blood
chemical_list: D006062:Gonadotropins; D013739:Testosterone; D000735:Androstenedione; D004958:Estradiol; D000324:Adrenocorticotropic Hormone; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D006854:Hydrocortisone
vernacular_title: Gipofizarno-gonadnaia i gipofizarno-kortiko-adrenalovaia sistemy u zdorovykh lits i bol'nykh ishemicheskoĭ bolezn'iu serdtsa v vozraste 60-89 let.