Gastric plasmacytoma with rod-shaped intracytoplasmic inclusions. Report of a case studied by light and electron microscopy and immunohistochemistry.
A 78-year-old man with primary gastric plasmacytoma showing massive rod-shaped intracytoplasmic inclusions is presented. The patient was initially diagnosed as having a benign gastric ulcer and underwent partial gastrectomy. Around the ulcer of the resected stomach specimen, diffuse proliferation of plasma cells with massive rod-shaped intracytoplasmic inclusions was noticed by light microscopy. Immunohistochemically, these cells were found to contain IgM-kappa-type immunoglobulin upon peroxidase-antiperoxidase (PAP) staining. Electron microscopy showed that the intracytoplasmic inclusions were localized in the rough endoplasmic reticulum and had a lattice structure with a periodicity of about 120 A.
Matsumoto
K
K
Department of Pathology, Nagasaki University School of Medicine, Japan.
Shikuwa
S
S
Kawase
Y
Y
Ooi
J
J
Honda
M
M
Ito
M
M
Sekine
I
I
Kunisaki
T
T
Ifuku
M
M
D000368:Aged; D003593:Cytoplasm / Q000648:ultrastructure*; D006801:Humans; D007150:Immunohistochemistry; D002479:Inclusion Bodies / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D010954:Plasmacytoma / Q000175:diagnosis / Q000473:pathology / Q000648:ultrastructure*; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000648:ultrastructure*