title: Fertility inhibition of RP1 by IncN plasmid pKM101.
abstract: IncN plasmids, including pKM101, strongly inhibit the conjugal transfer of cohabiting IncP plasmids. We localized the pKM101 DNA sufficient for this phenomenon to a 1.1-kilobase region (denoted fip). Two fip-deficient Tn5 insertion derivatives of pKM101 were isolated; neither affected other pKM101-mediated functions. fip did not inhibit either the synthesis of the IncP plasmid's sex pilus or its ability to mediate entry exclusion against other IncP plasmids.
authors.forename: S C
authors.initials: SC
authors.lastname: Winans
authors.forename: G C
authors.initials: GC
authors.lastname: Walker
mesh_terms: D001435:Bacteriophages / Q000235:genetics; D003227:Conjugation, Genetic; D004269:DNA, Bacterial; D004274:DNA, Recombinant; D010861:Fimbriae, Bacterial; D010957:Plasmids
chemical_list: D004269:DNA, Bacterial; D004274:DNA, Recombinant