title: Isolation and characterization of dipeptidyl peptidase IV from human meconium. Functional role of beta-casomorphins.
abstract: Dipeptidyl aminopeptidase IV (DAP-IV) (EC 3.4.14.1) was purified from meconium particles sedimenting at 105 000 X g. Its molecular properties and activity on synthetic and natural substrates (casomorphin and procasomorphin) were investigated.
authors.forename: C
authors.initials: C
authors.lastname: Caporale
authors.forename: A
authors.initials: A
authors.lastname: Fontanella
authors.forename: P
authors.initials: P
authors.lastname: Petrilli
authors.forename: P
authors.initials: P
authors.lastname: Pucci
authors.forename: M F
authors.initials: MF
authors.lastname: Molinaro
authors.forename: D
authors.initials: D
authors.lastname: Picone
authors.forename: S
authors.initials: S
authors.lastname: Auricchio
mesh_terms: D002364:Caseins / Q000378:metabolism; D018819:Dipeptidyl Peptidase 4; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases / Q000302:isolation & purification*; D010450:Endopeptidases / Q000302:isolation & purification*; D004723:Endorphins / Q000378:metabolism*; D006801:Humans; D007231:Infant, Newborn; D008470:Meconium / Q000201:enzymology*; D013379:Substrate Specificity
chemical_list: D002364:Caseins; D004723:Endorphins; C021968:beta-casomorphins; D010450:Endopeptidases; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; D018819:Dipeptidyl Peptidase 4