The effects of Cyclofenil on the Cervical Mucus Score (Insler).
Daily simultaneous cervical mucus evaluation and ultrasonography of the Graafian follicular growth and ovulation were studied (in the mid-cycle) in 8 infertile British women during 30 Cyclofenil-stimulated cycles, and compared with 18 non-stimulated normal ovulatory cycles in 12 subjects (controls). In the 16 Cyclofenil-induced ovulatory cycles, there was an early (5 days prior to the day of ultrasonic ovulation) Full Cervical Mucus Score (Insler) in 69% of the cycles, and the Full Cervical Mucus Score lasted for 7 days or more in 63% of the cycles. In 38%, there was persistence of the Full Cervical Mucus Score on the third day after ultrasonic ovulation. In the 14 Cyclofenil-treated anovulatory cycles, a Full Cervical Mucus Score was recorded on one or more occasions in the mid-cycle in 29% of the cycles. The classical teaching of prediction of the probable timing of ovulation by Cervical Mucus Scoring is not applicable to Cyclofenil-stimulated cycles.
Bhathena
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Patel
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Varma
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D000328:Adult; D002582:Cervix Mucus / Q000187:drug effects*; D003408:Cresols / Q000494:pharmacology*; D003506:Cyclofenil / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008597:Menstrual Cycle; D008991:Monitoring, Physiologic / Q000379:methods; D006080:Ovarian Follicle / Q000502:physiology; D010061:Ovulation Detection / Q000379:methods; D014463:Ultrasonography
D003408:Cresols; D003506:Cyclofenil