Efficacy and safety of two different dose levels of ganciclovir for the treatment of cytomegalovirus chorioretinitis in AIDS patients.
The effect of different dosages of ganciclovir on proved cytomegalovirus chorioretinitis was tested in a randomized trial on 11 homosexual men with AIDS. The effect of 5 mg/kg/day was as good as 10 mg/kg/day. The lower dosage had less toxicity.
Gaub
J
J
Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark.
Poulsen
A G
AG
Pedersen
C
C
Tinning
S
S
Højgaard
K
K
Thomson
M H
MH
Faber
V
V
Nielsen
J O
JO
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000212:Acyclovir / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000328:Adult; D000998:Antiviral Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D002825:Chorioretinitis / Q000188:drug therapy* / Q000209:etiology; D002986:Clinical Trials as Topic; D003586:Cytomegalovirus Infections / Q000188:drug therapy* / Q000209:etiology; D015774:Ganciclovir; D006801:Humans; D008297:Male; D008875:Middle Aged; D011897:Random Allocation
D000998:Antiviral Agents; D015774:Ganciclovir; D000212:Acyclovir