title: Bilateral testicular germ cell tumours: an increasing incidence and prevention by chemotherapy.
abstract: Of 120 patients with germ cell tumours of the testis, 6 (5%) developed contralateral tumours; 63 patients received cisplatin-based combination chemotherapy for metastatic disease and none developed contralateral disease. By contrast, of 57 patients treated with orchiectomy alone or abdominal radiotherapy, 5 (8.8%) developed contralateral disease.
authors.affiliation: CRC Wessex Regional Medical Oncology Unit, Southampton General Hospital.
authors.forename: J
authors.initials: J
authors.lastname: Thompson
authors.forename: C J
authors.initials: CJ
authors.lastname: Williams
authors.forename: J M
authors.initials: JM
authors.lastname: Whitehouse
authors.forename: G M
authors.initials: GM
authors.lastname: Mead
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D004407:Dysgerminoma / Q000517:prevention & control; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009373:Neoplasms, Germ Cell and Embryonal / Q000453:epidemiology / Q000517:prevention & control*; D013724:Teratoma / Q000517:prevention & control; D013736:Testicular Neoplasms / Q000453:epidemiology / Q000517:prevention & control*
chemical_list: D002945:Cisplatin