Bronchospasm: prevention and treatment.
We compared the results obtained in the treatment of bronchospastic conditions in two groups of 20 patients, one treated with an extempore combination of salbutamol (2 mg tablets) and oxatomide (30 mg tablets) and the other with salbutamol (2 mg tablets) alone. Positive results were obtained with the combination in 95% of cases, as against 55% in those treated with salbutamol alone. Generally speaking, treatment with the combination produced resolution of the bronchospasm, prevention of dyspnea attacks and an improvement in the respiratory status of the patients. The combination was well tolerated in all cases with no incidence of side effects, whereas in the patients on treatment with salbutamol alone, 3 cases of mild muscular tremors were observed, accompanied by tachycardia, but did not require discontinuation of the treatment.
Ghiringhelli
P
P
D000368:Aged; D000420:Albuterol / Q000009:adverse effects / Q000627:therapeutic use*; D001314:Auscultation; D001986:Bronchial Spasm / Q000188:drug therapy* / Q000503:physiopathology / Q000517:prevention & control; D004338:Drug Combinations; D005260:Female; D006634:Histamine H1 Antagonists / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010366:Peak Expiratory Flow Rate; D010879:Piperazines / Q000009:adverse effects / Q000627:therapeutic use*; D012129:Respiratory Function Tests
D004338:Drug Combinations; D006634:Histamine H1 Antagonists; D010879:Piperazines; C015408:oxatomide; D000420:Albuterol