title: Effect of prostaglandins PGE2 and PGF alpha 2 on the mean plaque size of bovine herpesvirus 1.
abstract: The effect of prostaglandins PGE2 and PGF alpha 2 on infectious bovine rhinotracheitis (IBR) virus (bovine herpesvirus 1; BHV-1) was studied by using the measurement of the mean size of plaques produced in cell culture by IBR/Cu5 strain. Three concentrations (0.1, 1 and 10 micrograms/ml) of prostaglandins, PGE2 and PGF alpha 2 were used. Each prostaglandin provoked an increase in the mean plaque size when compared to control plaques, at the concentrations 1 and 10 micrograms/ml for PGE2 and 10 micrograms/ml for PGF alpha 2.
authors.affiliation: Service de Virologie, Immunologie et Pathologie des maladies virales, Faculté de Médecine Vétérinaire, Université de Liège, Bruxelles, Belgique.
authors.forename: E
authors.initials: E
authors.lastname: Thiry
authors.forename: B
authors.initials: B
authors.lastname: Mignon
authors.forename: F
authors.initials: F
authors.lastname: Thalasso
authors.forename: P P
authors.initials: PP
authors.lastname: Pastoret
mesh_terms: D002478:Cells, Cultured; D015237:Dinoprost / Q000494:pharmacology*; D015232:Dinoprostone / Q000494:pharmacology*; D007242:Herpesvirus 1, Bovine / Q000187:drug effects* / Q000254:growth & development; D066298:In Vitro Techniques; D010948:Viral Plaque Assay; D014776:Virus Cultivation
chemical_list: D015237:Dinoprost; D015232:Dinoprostone