title: [Action of betaxolol on ventricular arrhythmias. Control of efficacy and tolerance by repetitive Holter recordings].
abstract: The ventricular anti-arrhythmic action of 20 mg of betaxolol per day was evaluated in 14 patients treated in monotherapy for a fortnight, by means of repeated Holter recordings. A significant decrease in the number of ischemic ventricular extrasystoles was observed during the diurnal and nocturnal periods. Repetitive ventricular events were also reduced. Betaxolol therefore appears to have a direct anti-arrhythmic action which is not related to its action on the heart rate. The other effects of beta-blocker treatment were also observed: a decrease in the systolic and diastolic blood pressure and sinus bradycardia.
authors.forename: F
authors.initials: F
authors.lastname: Fillette
authors.forename: S
authors.initials: S
authors.lastname: Lebrun
authors.forename: K
authors.initials: K
authors.lastname: Malkawi
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000009:adverse effects / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000188:drug therapy* / Q000503:physiopathology; D015784:Betaxolol; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D011412:Propanolamines / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D000319:Adrenergic beta-Antagonists; D011412:Propanolamines; D015784:Betaxolol
vernacular_title: Etude de l'action du bétaxolol sur les troubles du rythme ventriculaire. Contrôle de l'efficacité et de la tolérance par enregistrements de Holter répétés.