title: Asthma mortality in New Zealand: a two year national study.
abstract: The epidemic of deaths from bronchial asthma in New Zealand was investigated by a two-year national review of all deaths of persons under 70 years where "asthma" appeared in part I of a death certificate or in a coroner's report of cause of death. Information about the patients, the characteristics and management of their asthma and the circumstances of the fatal episode was obtained by interviewing relatives and general practitioners and perusal of hospital records. The reviewing panel of the asthma task force of the Medical Research Council considered 271 of the 342 deaths studied were due to asthma. A high national asthma mortality rate (5.1 per 100 000) was confirmed, with rates for Maoris (18.9) and Pacific Islanders (9.4) considerably higher than that for Europeans (3.4 per 100 000). After standardising for age and ethnic groups, there remained a threefold variation in mortality rates among health districts suggesting regional differences in prevalence, severity or management of asthma. No single cause for these high mortality rates was found. One-quarter of the deaths occurred in patients who had had previous life threatening attacks. Excessive use of bronchodilator drugs did not account for the high mortality rates, but inappropriate prolonged use of a home nebuliser may have delayed institution of other therapy in a few cases.
authors.forename: M R
authors.initials: MR
authors.lastname: Sears
authors.forename: H H
authors.initials: HH
authors.lastname: Rea
authors.forename: R
authors.initials: R
authors.lastname: Beaglehole
authors.forename: A J
authors.initials: AJ
authors.lastname: Gillies
authors.forename: P E
authors.initials: PE
authors.lastname: Holst
authors.forename: T V
authors.initials: TV
authors.lastname: O'Donnell
authors.forename: R P
authors.initials: RP
authors.lastname: Rothwell
authors.forename: D C
authors.initials: DC
authors.lastname: Sutherland
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000318:Adrenergic beta-Agonists / Q000009:adverse effects / Q000627:therapeutic use; D000328:Adult; D000336:Aerosols; D000368:Aged; D001249:Asthma / Q000188:drug therapy / Q000401:mortality*; D001993:Bronchodilator Agents / Q000009:adverse effects / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003644:Death Certificates; D005006:Ethnicity; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009520:New Zealand
chemical_list: D000305:Adrenal Cortex Hormones; D000318:Adrenergic beta-Agonists; D000336:Aerosols; D001993:Bronchodilator Agents