Ring-substituted beta-methoxyphenethylamines: a new class of psychotomimetic agents active in man.
Four members of a new class of psychotomimetic agents have been synthesized and evaluated in man. These compounds, which incorporate a beta-methoxy group onto a beta-phenethylamine sidechain, are the first reported psychotomimetics which are structural analogues of the neurotransmitter noradrenaline. These substances are more potent than the corresponding phenethylamines (lacking a beta-methoxy group) but less potent than the correspondingly substituted amphetamine derivatives.
Lemaire
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D
Jacob
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P
Shulgin
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AT
D000328:Adult; D000368:Aged; D055598:Chemical Phenomena; D002621:Chemistry; D005260:Female; D006213:Hallucinogens / Q000138:chemical synthesis*; D006801:Humans; D008297:Male; D008635:Mescaline / Q000494:pharmacology; D008875:Middle Aged; D009638:Norepinephrine / Q000031:analogs & derivatives; D014439:Tyramine / Q000031:analogs & derivatives* / Q000138:chemical synthesis
D006213:Hallucinogens; D008635:Mescaline; C008510:O-methyltyramine; D009638:Norepinephrine; D014439:Tyramine