title: Variation of transducer frequency output and receiver band-pass characteristics for improved detection and image characterization of solid breast masses.
abstract: A new approach has been used for ultrasound detection of small benign and malignant breast masses, namely, control of scattering in such a manner that a small mass can be easily recognized because of the effect of the scattering on the contrast between the mass and the surrounding normal tissue. Maintenance of good resolution as scattering is varied is an essential aspect of this approach. Image contrast is dependent on a number of instrumentation parameters but, in a fundamental sense, it is related to differences in the amount of scattering between a solid breast mass and the surrounding normal tissue. In the subject studies, modification of image contrast is accomplished by varying either the center frequency output of the transducer or the band-pass of the receiver. These approaches take advantage of differences in the frequency dependence of scattering coefficients of solid breast masses and normal tissue. A unique technique for varying center frequency without switching transducers was developed, namely, use of a wide bandwidth, co-polymer PVDF transducer, in combination with certain instrumentation conditions which allow the center frequency output of a single ultrasound transducer to vary over a relatively wide frequency range. Using this technique, an automatic B-mode ultrasound imaging breast instrument which allows emission of 3.5, 4.5, 6.5 and 11 MHz ultrasound frequencies from the same co-polymer transducer was used to examine patients with solid breast masses. Both a wide band-pass receiver, similar to that commonly used in clinical ultrasound systems and a tunable receiver (which allows variation of the band-pass from wide to narrow) was used with this automated system. Using the standard receiver system, it was found that there are advantages to having a range of transducer frequencies immediately available for breast examination. These include: (1) improved detection of masses located in highly attenuating regions of breast (by decreasing frequency); (2) availability of diagnostically relevant information at some one frequency which may not be apparent at other frequencies. Using the multiple frequency system and the standard receiver, it was found that the most appropriate examination frequencies for detection and diagnosis of fibroadenomas are higher frequencies (8 to 11 MHz). This is particularly true in the case of fibroadenomas in fatty breasts.(ABSTRACT TRUNCATED AT 400 WORDS)
authors.affiliation: Indiana University Medical Center, Indianapolis.
authors.forename: E
authors.initials: E
authors.lastname: Kelly-Fry
authors.forename: S T
authors.initials: ST
authors.lastname: Morris
authors.forename: V P
authors.initials: VP
authors.lastname: Jackson
authors.forename: R W
authors.initials: RW
authors.lastname: Holden
authors.forename: N T
authors.initials: NT
authors.lastname: Sanghvi
mesh_terms: D000232:Adenofibroma / Q000175:diagnosis; D000328:Adult; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis*; D002278:Carcinoma in Situ / Q000175:diagnosis; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000175:diagnosis; D004867:Equipment Design; D005260:Female; D006801:Humans; D007089:Image Enhancement; D008875:Middle Aged; D012542:Scattering, Radiation; D014159:Transducers; D014463:Ultrasonography / Q000295:instrumentation / Q000379:methods*