title: [Periarteritis nodosa: clinical and therapeutic study of 126 patients followed-up during 23 years].
abstract: A hundred and twenty-six patients with systemic polyarteritis nodosa (PN) were studied over a 23 year period. The clinical symptoms and paraclinical data of PN are reviewed, and the results obtained by the different therapeutic approaches used during this period are presented: steroids alone and then associated with immunosuppressors and, in the most recent cases, associated with plasma exchange. The actuarial survival of patients in this retrospective and unrandomised series was comparable whether steroids were used alone or with immunosuppressors. The different therapeutic approaches in PAN are discussed especially with respect to the role of immunosuppressor therapy and plasma exchange.
authors.forename: L
authors.initials: L
authors.lastname: Guillevin
authors.forename: J
authors.initials: J
authors.lastname: Fechner
authors.forename: P
authors.initials: P
authors.lastname: Godeau
authors.forename: O
authors.initials: O
authors.lastname: Blétry
authors.forename: B
authors.initials: B
authors.lastname: Wechsler
authors.forename: G
authors.initials: G
authors.lastname: Herreman
authors.forename: S
authors.initials: S
authors.lastname: Herson
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010951:Plasma Exchange; D010488:Polyarteritis Nodosa / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D013997:Time Factors
chemical_list: D000305:Adrenal Cortex Hormones; C006871:calcium heparin; D006493:Heparin
vernacular_title: Périartérite noueuse: étude clinique et thérapeutique de 126 malades étudiés en 23 ans.