title: The human placental bed: histology, immunohistochemistry and pathology.
abstract: There has been much interest recently on local intra-uterine materno-fetal interactions particularly in the placental bed where cellular relationships between mother and fetus are at their most intimate. While few histopathologists are expected to interpret formal placental bed biopsy specimens, confrontation with tissue from this site is common following abortion, post-partum haemorrhage or molar gestation. This review gives an account of recent advances in our knowledge of the histology, immunohistochemistry and pathology of the placental bed. It focuses particularly on extravillous trophoblast populations and their relationship to maternal cells and emphasizes the importance of vascular changes.
authors.affiliation: Department of Pathology, University of Leeds, UK.
authors.forename: M
authors.initials: M
authors.lastname: Wells
authors.forename: J N
authors.initials: JN
authors.lastname: Bulmer
mesh_terms: D001158:Arteries / Q000276:immunology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D037102:Lectins / Q000378:metabolism; D010920:Placenta / Q000033:anatomy & histology* / Q000378:metabolism / Q000473:pathology; D010921:Placenta Accreta / Q000473:pathology; D010922:Placenta Diseases / Q000473:pathology; D006473:Postpartum Hemorrhage / Q000473:pathology; D011247:Pregnancy; D011518:Proto-Oncogene Proteins / Q000378:metabolism; D014328:Trophoblastic Neoplasms / Q000473:pathology; D014327:Trophoblasts / Q000276:immunology
chemical_list: D037102:Lectins; D011518:Proto-Oncogene Proteins