title: Severe neurological sequelae of childhood bacterial meningitis.
abstract: Bacterial meningitis remains the most common type of central nervous system infection in both developing and developed countries. Despite modern antimicrobial chemotherapy, the incidence of severe neurological sequelae remains high. We review the pathogenesis of these sequelae and correlate them with computed tomography (CT) appearances. Early diagnosis and appropriate chemotherapy remain the cornerstones of management. Early and accurate diagnosis of complicating space-occupying lesions with the aid of CT and appropriate aggressive therapy are suggested if the prognosis is to be improved.
authors.forename: M
authors.initials: M
authors.lastname: Moodley
authors.forename: M R
authors.initials: MR
authors.lastname: Bullock
mesh_terms: D001284:Atrophy; D001922:Brain Abscess / Q000209:etiology; D001929:Brain Edema / Q000209:etiology; D002493:Central Nervous System Diseases / Q000209:etiology*; D002540:Cerebral Cortex / Q000098:blood supply / Q000473:pathology; D002544:Cerebral Infarction / Q000209:etiology; D002675:Child, Preschool; D013354:Empyema, Subdural / Q000209:etiology; D004678:Encephalomalacia / Q000209:etiology; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology; D007223:Infant; D007427:Intracranial Pressure; D008581:Meningitis / Q000150:complications* / Q000209:etiology; D013353:Subdural Effusion / Q000209:etiology; D014657:Vasculitis / Q000209:etiology