Somatostatin stimulates ACTH release in brown trout (Salmo trutta L.).
Injections of somatostatin (SRIF) produced small but significant increases in the serum cortisol concentration of brown trout in which endogenous ACTH secretion was suppressed with dexamethasone. SRIF did not stimulate in vitro secretion of cortisol by trout interrenal tissue. These results suggest that SRIF may play a minor role in ACTH secretion in salmonids.
Langhorne
P
P
D000324:Adrenocorticotropic Hormone / Q000378:metabolism* / Q000494:pharmacology; D000818:Animals; D003907:Dexamethasone / Q000494:pharmacology; D013006:Growth Hormone / Q000494:pharmacology; D006854:Hydrocortisone / Q000097:blood; D012487:Salmonidae / Q000097:blood*; D013004:Somatostatin / Q000494:pharmacology*; D014337:Trout / Q000097:blood*
D013004:Somatostatin; D003907:Dexamethasone; D000324:Adrenocorticotropic Hormone; D013006:Growth Hormone; D006854:Hydrocortisone