title: [Infection with equine herpesvirus and its manifestation in the central nervous system of the horse].
abstract: Infections with EHV1 can lead to manifestation at the CNS of horses followed by encephalomyelitis and "equine stroke". Horse experiments could confirm the clinical picture and gave links to the potential pathogenesis of the disease. We also have been in the position to isolate and characterize an EHV4 virus out of the brain of a horse with CNS disorders. The two viruses carry different biological properties which obviously dominate the pathogenesis. These properties as well as experimental and field cases are described and different diagnostic tests are discussed.
authors.affiliation: Bayer AG, Geschäftsbereich Veterinärmedizin, Forschung und Entwicklung Biologie, Leverkusen.
authors.forename: P
authors.initials: P
authors.lastname: Thein
authors.forename: K
authors.initials: K
authors.lastname: Brown
mesh_terms: D000818:Animals; D001927:Brain Diseases / Q000175:diagnosis / Q000209:etiology / Q000662:veterinary*; D006566:Herpesviridae Infections / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D006734:Horse Diseases / Q000175:diagnosis; D006736:Horses
vernacular_title: Infektion mit equinen Herpesviren und Manifestation am Zentralnervensystem beim Pferd.