Tyrosine hydroxylase and 28K-vitamin D-dependent calcium binding protein are localized in different subpopulations of periglomerular cells of the rat olfactory bulb.
Successive incubations of rat olfactory bulb cryostat sections with antibodies against the chick 28K-vitamin D-dependent calcium (Ca) binding protein and tyrosine hydroxylase were performed, and the distribution of the label was examined in the fluorescence microscope. Both antibodies labeled cells and processes in highest number in the glomerular layer. The two immunopositivities were not co-localized in the same neurons. This suggests that the presence of this Ca-binding protein is not a necessary prerequisite for dopaminergic neurotransmission in periglomerular neurons.
Halász
N
N
Hökfelt
T
T
Norman
A W
AW
Goldstein
M
M
D000818:Animals; D002135:Calcium-Binding Proteins / Q000378:metabolism*; D004298:Dopamine / Q000502:physiology; D005260:Female; D005455:Fluorescent Antibody Technique; D008297:Male; D009830:Olfactory Bulb / Q000378:metabolism* / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D011921:Rats, Inbred WKY; D064030:S100 Calcium Binding Protein G / Q000378:metabolism*; D009435:Synaptic Transmission; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism*
D002135:Calcium-Binding Proteins; D064030:S100 Calcium Binding Protein G; D014446:Tyrosine 3-Monooxygenase; D004298:Dopamine