title: Newcastle disease virus-infected splenocytes express the proopiomelanocortin gene.
abstract: Infection of murine splenocytes with Newcastle disease virus results in expression of the proopiomelanocortin gene as determined by dot and northern blot analysis of total cellular and poly(A)+ cytoplasmic RNA. These data provide the first evidence that the precursor protein for adrenocorticotropin and beta-endorphin can be synthesized by lymphoid cells.
authors.forename: H J
authors.initials: HJ
authors.lastname: Westly
authors.forename: A J
authors.initials: AJ
authors.lastname: Kleiss
authors.forename: K W
authors.initials: KW
authors.lastname: Kelley
authors.forename: P K
authors.initials: PK
authors.lastname: Wong
authors.forename: P H
authors.initials: PH
authors.lastname: Yuen
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000096:biosynthesis / Q000378:metabolism; D000818:Animals; D004723:Endorphins / Q000096:biosynthesis; D005786:Gene Expression Regulation; D008214:Lymphocytes / Q000378:metabolism*; D051379:Mice; D008807:Mice, Inbred BALB C; D009522:Newcastle disease virus / Q000502:physiology*; D011061:Poly A / Q000032:analysis; D011333:Pro-Opiomelanocortin / Q000096:biosynthesis* / Q000235:genetics; D012333:RNA, Messenger / Q000032:analysis; D013154:Spleen / Q000166:cytology / Q000378:metabolism; D001615:beta-Endorphin
chemical_list: D004723:Endorphins; D012333:RNA, Messenger; D011061:Poly A; D001615:beta-Endorphin; D011333:Pro-Opiomelanocortin; D000324:Adrenocorticotropic Hormone