title: Premenstrual tension syndrome in rapid-cycling bipolar affective disorder.
abstract: Premenstrual tension syndrome (PMS) and rapid-cycling bipolar affective disorder have similarities of symptoms, cyclical mood swings, and putative neurotransmitter dysfunction. The possible relationship between these disorders was assessed by evaluating 25 patients with rapid-cycling disorders and 25 normal controls for PMS symptoms. Patients with rapid-cycling affective disorder had an increased tendency to have more severe forms of PMS. In addition, patients with rapid-cycling disorders and more severe forms of PMS tended to cycle more frequently. The significance of this finding and its clinical implications are discussed.
authors.forename: W A
authors.initials: WA
authors.lastname: Price
authors.forename: L
authors.initials: L
authors.lastname: DiMarzio
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000150:complications* / Q000503:physiopathology / Q000523:psychology; D005260:Female; D006801:Humans; D008875:Middle Aged; D018377:Neurotransmitter Agents / Q000502:physiology; D011293:Premenstrual Syndrome / Q000150:complications* / Q000503:physiopathology / Q000523:psychology
chemical_list: D018377:Neurotransmitter Agents