Lack of pathogenicity of five serotype 2 infectious bursal disease viruses in chickens.
The pathogenic potential of five strains of serotype 2 infectious bursal disease virus (IBDV) for specific-pathogen-free chickens was examined. There were no gross or microscopic lesions in the inoculated chickens. Bursa-to-body-weight ratios of IBDV-infected chickens were not significantly different from those of uninfected controls. Virus-neutralizing antibodies to IBDV of serotype 2, but not serotype 1, were detected in infected chickens. This study indicated that the serotype 2 viruses examined were infectious but not pathogenic in chickens.
Ismail
N M
NM
Ohio Agricultural Research and Development Center, Ohio State University, Wooster 44691.
Saif
Y M
YM
Moorhead
P D
PD
D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis; D002645:Chickens / Q000276:immunology / Q000382:microbiology*; D007243:Infectious bursal disease virus / Q000276:immunology / Q000472:pathogenicity*; D009500:Neutralization Tests; D012087:Reoviridae / Q000472:pathogenicity*; D012703:Serotyping / Q000662:veterinary; D013045:Species Specificity
D000914:Antibodies, Viral