title: [Anxiolytic action of beta-carbolines in rats].
abstract: The decreased sensitivity to the anxiolytic action of diazepam, BC-3-KEE, IME-6MEO-TGBC, IME-6MEO-DBC was shown in rats with experimental alcoholism. The degree of the decreased sensitivity was dependent on the affinity of the compounds to benzodiazepine receptors.
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Burov
authors.forename: S N
authors.initials: SN
authors.lastname: Orekhov
authors.forename: N N
authors.initials: NN
authors.lastname: Vedernikova
mesh_terms: D000437:Alcoholism / Q000188:drug therapy; D000818:Animals; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001640:Bicuculline / Q000494:pharmacology; D002243:Carbolines / Q000494:pharmacology*; D003975:Diazepam / Q000494:pharmacology; D004353:Drug Evaluation, Preclinical; D004924:Escape Reaction / Q000187:drug effects; D006801:Humans; D007211:Indoles / Q000494:pharmacology*; D008297:Male; D051381:Rats; D011963:Receptors, GABA-A / Q000187:drug effects
chemical_list: D014151:Anti-Anxiety Agents; D002243:Carbolines; D007211:Indoles; D011963:Receptors, GABA-A; D003975:Diazepam; D001640:Bicuculline
vernacular_title: Anksioliticheskaia aktivnost' nekotorykh beta-karbolinov u krys.