[Treatment of arterial hypertension in diabetics. Contribution of converting enzyme inhibitors].
The treatment of arterial hypertension in diabetic patients still raises numerous problems. In this type of patients, the most commonly prescribed drugs (beta-blockers, diuretics, antihypertensive agents acting on the central nervous system) have troublesome and potentially detrimental effects (e.g. effects on lipids). The new categories of antihypertensive drugs recently introduced (angiotensin-converting enzyme inhibitors, calcium antagonists) are likely to be most useful in these patients. In an open trial in non-insulin-dependent diabetics with arterial hypertension followed-up for 1 year, enalapril administered alone has proved effective and devoid of clinical and biochemical side-effects. If these results are confirmed, angiotensin-converting enzyme inhibitors will rank high as first-choice treatment of arterial hypertension in diabetics.
Passa
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Marre
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Leblanc
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H
D000319:Adrenergic beta-Antagonists / Q000009:adverse effects; D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents / Q000009:adverse effects; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D002216:Captopril / Q000627:therapeutic use; D003920:Diabetes Mellitus / Q000178:diet therapy; D003924:Diabetes Mellitus, Type 2 / Q000628:therapy; D003925:Diabetic Angiopathies / Q000628:therapy*; D004232:Diuretics / Q000009:adverse effects; D004656:Enalapril / Q000627:therapeutic use*; D006801:Humans; D006973:Hypertension / Q000628:therapy*; D009765:Obesity; D014665:Vasodilator Agents / Q000009:adverse effects
D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers; D004232:Diuretics; D014665:Vasodilator Agents; D004656:Enalapril; D002216:Captopril
Traitement de l'hypertension artérielle chez les diabétiques. Apport des inhibiteurs de l'enzyme de conversion.