title: Psychosocial and physiological factors in relation to blood pressure at rest--a study of Swedish men in their upper twenties.
abstract: The interrelationships between psychosocial factors, several physiological variables and blood pressure (BP) were investigated in 88 young men (aged 26-32 years) in whom high, intermediate or low BP had been recorded at the age of 18 years. In the original high BP group, venous plasma noradrenaline was normal but adrenaline levels elevated. At the follow-up adrenaline correlated with systolic blood pressure (SBP), and this was also so after controlling for overweight and serum gamma-glutamyltranspeptidase [gamma-GT, a marker for alcohol consumption, which showed an independent association with diastolic blood pressure (DBP)]. Low assertiveness (low scores of verbal and indirect aggression) correlated with high BPs, even after controlling for other psychosocial variables. Several associations between psychosocial job variables and physiological variables were found. Among self-reported job variables, excessive 'demands' and 'bossing others' (but not 'decision latitude' or 'psychosocial conflict') were associated with high SBP. Habitual smoking of cigarettes was not associated with BP at rest, but influenced several associations between psychosocial and physiological variables. Men with high BP at rest and low plasma renin activity (PRA) reported more psychosocial problems at work and lower assertiveness than other groups.
authors.forename: T
authors.initials: T
authors.lastname: Theorell
authors.forename: P
authors.initials: P
authors.lastname: Hjemdahl
authors.forename: F
authors.initials: F
authors.lastname: Ericsson
authors.forename: A
authors.initials: A
authors.lastname: Kallner
authors.forename: S
authors.initials: S
authors.lastname: Knox
authors.forename: A
authors.initials: A
authors.lastname: Perski
authors.forename: J
authors.initials: J
authors.lastname: Svensson
authors.forename: B
authors.initials: B
authors.lastname: Tidgren
authors.forename: D
authors.initials: D
authors.lastname: Waller
mesh_terms: D000328:Adult; D001794:Blood Pressure; D001835:Body Weight; D004837:Epinephrine / Q000097:blood; D004912:Erythrocytes / Q000032:analysis; D006339:Heart Rate; D006801:Humans; D008297:Male; D009638:Norepinephrine / Q000097:blood; D010551:Personality; D010556:Personality Tests; D011188:Potassium / Q000097:blood; D012044:Regression Analysis; D012083:Renin / Q000097:blood; D012146:Rest; D012907:Smoking; D012964:Sodium / Q000097:blood; D013548:Sweden; D005723:gamma-Glutamyltransferase / Q000097:blood
chemical_list: D012964:Sodium; D005723:gamma-Glutamyltransferase; D012083:Renin; D011188:Potassium; D009638:Norepinephrine; D004837:Epinephrine