[Persistent neurological syndrome after treatment with lithium salts. Toxicity of the lithium-neuroleptic combination?].
In 2 patients receiving a long-term lithium carbonate therapy, persistent cerebellar, pyramidal, and extrapyramidal signs were observed, following a febrile pulmonary event. The mechanism of these disturbances is discussed, emphasizing the lithium-neuroleptics interaction as well as the possible role of hyperthermia.
Habib
M
M
Khalil
R
R
le Pensec-Bertrand
D
D
Ali-Cherif
A
A
Bongrand
M C
MC
Crevat
A
A
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D001714:Bipolar Disorder / Q000188:drug therapy; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D005260:Female; D005334:Fever / Q000150:complications; D006801:Humans; D008094:Lithium / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000139:chemically induced* / Q000175:diagnosis
D014150:Antipsychotic Agents; D008094:Lithium
Syndrome neurologique persistant après traitement par les sels de lithium. Toxicité de l'association lithium-neuroleptiques?