Experimental analysis of antihypertensive properties of S 5984 and its constituents: tertatolol and indapamide.
S 5984 is a combination of tertatolol (S 2395-1) and indapamide. A positive synergism between these two constituents with regard to antihypertensive activity was demonstrated in the rat and the dog.
Marmo
E
E
Lampa
E
E
Rosatti
F
F
Berrino
L
L
Russo
S
S
Romano
A R
AR
Matera
C
C
D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D003900:Desoxycorticosterone / Q000494:pharmacology; D004232:Diuretics / Q000494:pharmacology*; D004285:Dogs; D004338:Drug Combinations / Q000494:pharmacology; D007190:Indapamide / Q000494:pharmacology*; D008297:Male; D011412:Propanolamines / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D013876:Thiophenes
D000319:Adrenergic beta-Antagonists; D004232:Diuretics; D004338:Drug Combinations; D011412:Propanolamines; D013876:Thiophenes; C049590:S 5984; D003900:Desoxycorticosterone; C005632:tertatolol; D007190:Indapamide