[An immunosorbent method for the quantitative determination of antiliver autoantibodies in patients with viral hepatitis].
Autoimmune processes in patients with mild, moderate and severe forms of viral hepatitis B have been studied with the use of a new immunosorbent method for the quantitative determination of autoantibodies (auto-Ab), developed by the authors. The immunosorbent has been obtained on the basis of granulated aerosil, an active protein-adsorbent agent used as a solid antigen carrier. The level of auto-Ab in patients with all forms of viral hepatitis B has been found to exceed the content of such antibodies in practically healthy persons. Besides, in patients with severe and prolonged forms of the disease the content of antihepatic auto-Ab has been found to remain high even after clinical convalescence, which is indicative of the continuation of the autoimmune process.
Tertyshnaia
E V
EV
Gavura
V V
VV
Lutsiuk
N B
NB
D000293:Adolescent; D000328:Adult; D000368:Aged; D000936:Antigen-Antibody Complex / Q000032:analysis; D001323:Autoantibodies / Q000032:analysis*; D001327:Autoimmune Diseases / Q000276:immunology; D005260:Female; D005782:Gels; D006509:Hepatitis B / Q000276:immunology*; D006801:Humans; D007163:Immunosorbent Techniques; D008099:Liver / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D012822:Silicon Dioxide
D000936:Antigen-Antibody Complex; D001323:Autoantibodies; D005782:Gels; D012822:Silicon Dioxide
Immunosorbentnyĭ metod kolichestvennogo opredeleniia protivopechenochnykh autoantitel u bol'nykh virusnym gepatitom.