title: The importance of protease histochemistry in pathology.
abstract: The histochemical demonstration of the activities of proteases, based in the majority of cases on the use of discriminating synthetic substrates (aminoacyl or peptidyl derivatives of 4-methoxy-2-naphthylamine [MNA]), has proved very valuable in pathology. Its importance is illustrated by three topics investigated in our laboratory, namely lymphocytes, malabsorption syndrome and atherosclerosis.
authors.forename: Z
authors.initials: Z
authors.lastname: Lojda
mesh_terms: D000626:Aminopeptidases / Q000032:analysis; D000818:Animals; D001158:Arteries / Q000201:enzymology; D001161:Arteriosclerosis / Q000201:enzymology*; D018826:CD13 Antigens; D020789:Cathepsin C; D003979:Diazonium Compounds; D018819:Dipeptidyl Peptidase 4; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases / Q000032:analysis; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007413:Intestinal Mucosa / Q000201:enzymology; D008214:Lymphocytes / Q000201:enzymology*; D008286:Malabsorption Syndromes / Q000201:enzymology*; D008297:Male; D008871:Microvilli / Q000201:enzymology; D010447:Peptide Hydrolases / Q000032:analysis*; D011817:Rabbits; D005723:gamma-Glutamyltransferase / Q000032:analysis
chemical_list: D003979:Diazonium Compounds; C020747:Fast Blue B; D005723:gamma-Glutamyltransferase; D010447:Peptide Hydrolases; D000626:Aminopeptidases; D018826:CD13 Antigens; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; D020789:Cathepsin C; C100151:dipeptidyl peptidase II; D018819:Dipeptidyl Peptidase 4