Effect of somatostatin on organ blood flow in anaesthetized cats.
Effect of somatostatin infusion (100 ng/min-61 pmol/min) on organ blood flow was studied in anaesthetized cats. Total blood flow in the superior mesenteric, left renal, lienal, inferior caval veins and the sagittal sinus was measured by the H2-clearance method. Vascular resistance decreased in the small intestine, in the hind limb and in the kidney due to somatostatin infusion. Somatostatin seems to have direct vasodilatory effect in different vascular beds.
Hamar
J
J
Iripchanov
B B
BB
Demchenko
I T
IT
Dézsi
L
L
Moskalenko
J J
JJ
D000768:Anesthesia, General; D000818:Animals; D001775:Blood Circulation / Q000187:drug effects*; D001794:Blood Pressure / Q000187:drug effects; D002415:Cats; D002560:Cerebrovascular Circulation / Q000187:drug effects; D006614:Hindlimb / Q000098:blood supply; D012039:Regional Blood Flow / Q000187:drug effects; D012079:Renal Circulation / Q000187:drug effects; D013004:Somatostatin / Q000494:pharmacology*; D013152:Splanchnic Circulation / Q000187:drug effects; D013154:Spleen / Q000098:blood supply; D014655:Vascular Resistance / Q000187:drug effects
D013004:Somatostatin