title: Highly potent and selective ligands for a new class H3 of histamine receptor.
abstract: The third histamine receptor was first indentified on brain neurons and seems to be present in other cells such as lung mast cells. Hence the novel and potent H3-receptor agonist (R) alpha-methylhistamine might find therapeutic applications in allergic diseases.
authors.affiliation: Unité 109 de Neurobiologie et Pharmacologie, Centre Paul Broca de l'INSERM, Paris, France.
authors.forename: J M
authors.initials: JM
authors.lastname: Arrang
authors.forename: M
authors.initials: M
authors.lastname: Garbarg
authors.forename: J C
authors.initials: JC
authors.lastname: Lancelot
authors.forename: J M
authors.initials: JM
authors.lastname: Lecomte
authors.forename: H
authors.initials: H
authors.lastname: Pollard
authors.forename: M
authors.initials: M
authors.lastname: Robba
authors.forename: W
authors.initials: W
authors.lastname: Schunack
authors.forename: J C
authors.initials: JC
authors.lastname: Schwartz
mesh_terms: D000818:Animals; D008761:Methylhistamines; D010880:Piperidines; D011869:Radioligand Assay; D051381:Rats; D011968:Receptors, Histamine / Q000187:drug effects / Q000302:isolation & purification*; D018100:Receptors, Histamine H3
chemical_list: D008761:Methylhistamines; D010880:Piperidines; D011968:Receptors, Histamine; D018100:Receptors, Histamine H3; C052075:thioperamide