title: [Dynamic immunologic reactivity of schizophrenics during psychopharmacotherapy as exemplified by virus-induced reactions of the blood lymphocytes].
abstract: Clinical immunological investigation of 149 schizophrenic patients, 89 healthy donors and 38 infected patients revealed the fact of high lymphocyte reactivity in schizophrenic patients inhabitants of the city of Tomsk and Tomsk Province to the viral antigens of herpes simplex and Far-Eastern encephalitis. The course of herpes-induced immune responses was largely associated with the course of psychopathological signs. The role of immunomodulating and desensitizing effects of psychotropic therapy is discussed.
authors.forename: T I
authors.initials: TI
authors.lastname: Nevidimova
authors.forename: O A
authors.initials: OA
authors.lastname: Vasil'eva
authors.forename: E D
authors.initials: ED
authors.lastname: Krasik
authors.forename: G V
authors.initials: GV
authors.lastname: Logvinovich
mesh_terms: D000293:Adolescent; D000328:Adult; D000937:Antigen-Antibody Reactions; D000956:Antigens, Viral / Q000276:immunology*; D004197:Disease Reservoirs; D004669:Encephalitis Viruses, Tick-Borne / Q000276:immunology*; D005260:Female; D006801:Humans; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D011619:Psychotropic Drugs / Q000627:therapeutic use*; D012397:Rosette Formation; D012559:Schizophrenia / Q000188:drug therapy / Q000276:immunology*; D012800:Siberia; D018139:Simplexvirus / Q000276:immunology*
chemical_list: D000956:Antigens, Viral; D011619:Psychotropic Drugs
vernacular_title: Dinamika immunologicheskoĭ reaktivnosti bol'nykh shizofrenieĭ v protsesse psikhofarmakoterapii na primere virusindutsirovannykh reaktsiĭ limfotsitov krovi.