title: Virucidal effect of chlorinated water containing cyanuric acid.
abstract: The inhibitory influence of cyanuric acid on the virucidal effect of chlorine was studied. The time required for 99.9% inactivation of ten enteroviruses and two adenoviruses by 0.5 mg/l free available chlorine at pH 7.0 and 25 degrees C was prolonged approximately 4.8-28.8 times by the addition of 30 mg/l cyanuric acid. Comparative inactivation of poliovirus 1 by free available chlorine with or without cyanuric acid revealed the following. The inactivation rate by 1.5 mg/l free available chlorine with 30 mg/l cyanuric acid or by 0.5 mg/l free available chlorine with 1 mg/l cyanuric acid was slower than by 0.5 mg/l free available chlorine alone. Temperature and pH did not affect the inhibitory influence of cyanuric acid on the disinfectant action of chlorine. In the swimming-pool and tap water, cyanuric acid delayed the virucidal effect of chlorine as much as in the 'clean' condition of chlorine-buffered distilled water. The available chlorine value should be increased to 1.5 mg/l when cyanuric acid is used in swimming-pool water.
authors.affiliation: Aichi Prefectural Institute of Public Health, Nagoya, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yamashita
authors.forename: K
authors.initials: K
authors.lastname: Sakae
authors.forename: Y
authors.initials: Y
authors.lastname: Ishihara
authors.forename: S
authors.initials: S
authors.lastname: Isomura
authors.forename: H
authors.initials: H
authors.lastname: Inoue
mesh_terms: D000256:Adenoviridae / Q000187:drug effects; D000998:Antiviral Agents; D002713:Chlorine / Q000633:toxicity*; D004347:Drug Interactions; D004770:Enterovirus / Q000187:drug effects; D006863:Hydrogen-Ion Concentration; D017955:Poliovirus / Q000187:drug effects; D013551:Swimming Pools; D013696:Temperature; D013997:Time Factors; D014227:Triazines / Q000633:toxicity*
chemical_list: D000998:Antiviral Agents; D014227:Triazines; D002713:Chlorine; C004632:cyanuric acid