title: [Age aspects of receptor-effector reactions and the regulation of adenylate cyclase activity].
abstract: The present-day notions on the trends and mechanisms of changes in the activity of the cyclic nucleotide system are considered in the age aspect. Their role in disturbances of the neurohumoral regulation processes at the molecular level is discussed. Biochemical mechanisms of changes in the receptor-effector reactions are analyzed. An analysis of these changes is very important for elucidating general regularities of the cyclase system functioning with disturbances of biochemical regulation at the membrane and cell levels.
authors.forename: S G
authors.initials: SG
authors.lastname: Burchinskiĭ
authors.forename: O K
authors.initials: OK
authors.lastname: Kul'chitskiĭ
mesh_terms: D000262:Adenylyl Cyclases / Q000378:metabolism / Q000502:physiology*; D000273:Adipose Tissue / Q000378:metabolism / Q000502:physiology; D000375:Aging; D000818:Animals; D001773:Blood Cells / Q000378:metabolism / Q000502:physiology; D002320:Cardiovascular Physiological Phenomena; D002319:Cardiovascular System / Q000378:metabolism; D002490:Central Nervous System / Q000378:metabolism / Q000502:physiology; D000242:Cyclic AMP / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D008099:Liver / Q000378:metabolism / Q000502:physiology; D008560:Membrane Fluidity; D018377:Neurotransmitter Agents / Q000502:physiology*; D011956:Receptors, Cell Surface / Q000378:metabolism / Q000502:physiology*
chemical_list: D018377:Neurotransmitter Agents; D011956:Receptors, Cell Surface; D000242:Cyclic AMP; D000262:Adenylyl Cyclases
vernacular_title: Vozrastnye aspekty retseptor-éffektornykh reaktsiĭ i reguliatsii aktivnosti adenilattsiklazy.