title: Level of plasma fibronectin in patients with breast cancer.
abstract: Plasma fibronectin was determined by laser nephelometric immunoassay in two populations: healthy individuals and patients with metastatic or non-metastatic breast cancer. The results showed that the fibronectin concentration was higher in the patient group than in the healthy controls of similar age, with a significant difference (p less than 0.05). The patients who had metastatic breast cancer tended to show higher levels than those with no detectable metastasis, but such a difference was not statistically significant. Since fibronectin is sensitive to clinical events unrelated to the malignancy status, it does not seem suitable as a tumor marker.
authors.affiliation: Laboratoire de Biochimie Médicale, Hôtel-Dieu, Rennes, France.
authors.forename: A
authors.initials: A
authors.lastname: Ruelland
authors.forename: P
authors.initials: P
authors.lastname: Kerbrat
authors.forename: C
authors.initials: C
authors.lastname: Clerc
authors.forename: B
authors.initials: B
authors.lastname: Legras
authors.forename: L
authors.initials: L
authors.lastname: Cloarec
mesh_terms: D000293:Adolescent; D000328:Adult; D001943:Breast Neoplasms / Q000097:blood* / Q000473:pathology; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000097:blood* / Q000473:pathology; D005260:Female; D005353:Fibronectins / Q000097:blood*; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging
chemical_list: D005353:Fibronectins