Metabolic response to different forms of physical exercise in type I diabetics and the duration of the glucose lowering effect.
In order to analyse the metabolic effect of exercise nine well-controlled type I diabetics took part in four series of tests: (i) a short exercise with maximal work load, (ii) a 30 min exercise with half maximal work load, (iii) a 3 x 10 min interval exercise and (iv) control without exercise. Exercises were performed on a bicycle ergometer starting at 09.00 h. On the test days, only two thirds of the normal insulin dose was given. Blood glucose, free insulin, glucagon, catecholamines, growth hormone, cortisol, lactate and pyruvate were measured during the exercise and the following 60 min. Glucose profiles were taken until 17.15 h. The short exercise with maximal work load did not affect blood glucose, the half maximal exercise and the interval exercise resulted in a decrease. Short rest phases did not modify the glucose lowering effect nor the overall response of counterregulatory hormones. A snack following exercise resulted in a total compensation of the glucose lowering effect.
Hübinger
A
A
Ridderskamp
I
I
Lehmann
E
E
Gries
F A
FA
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D005260:Female; D006728:Hormones / Q000097:blood; D006801:Humans; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D008297:Male; D008875:Middle Aged; D018377:Neurotransmitter Agents / Q000097:blood; D005082:Physical Exertion; D011773:Pyruvates / Q000097:blood; D019289:Pyruvic Acid; D013997:Time Factors
D001786:Blood Glucose; D006728:Hormones; D007773:Lactates; D018377:Neurotransmitter Agents; D011773:Pyruvates; D019344:Lactic Acid; D019289:Pyruvic Acid