The treatment of acute necrotizing pancreatitis, using a mediastinoscope postoperatively and antiseptic rinses.
In the years before 1981, the mortality of acute necrotizing pancreatitis was about 70%. By better timing of surgery and intra- as well as postoperative rinsing with povidone-iodine mortality could be lowered to 50%. Leaving the peritoneal cavity open enables easy surgical access to further septic complications. In 10 patients with conservative closure of the abdominal wall five patients died. In seven patients whose abdominal wall was left open and the pancreatic space packed, with the possibility of endoscopic removal of further necroses, only one patient died.
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D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008481:Mediastinoscopy; D008875:Middle Aged; D009336:Necrosis; D010179:Pancreas / Q000473:pathology / Q000601:surgery; D010195:Pancreatitis / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D011183:Postoperative Complications / Q000517:prevention & control; D011205:Povidone / Q000031:analogs & derivatives*; D011206:Povidone-Iodine / Q000627:therapeutic use*; D013630:Tampons, Surgical
D000891:Anti-Infective Agents, Local; D011206:Povidone-Iodine; D011205:Povidone