title: [Malignant myoepithelioma of the breast (histological, immunomorphological and electron microscopic study)].
abstract: A rare kind of a breast tumor was identified in a woman of 47. The disease ran a malignant course and presented difficulties for morphological verification. Histological appearance showed areas of spindle-shaped or lamellar cells occasionally encircled with homogeneous hyalin-like substance. Locally, there were structures of alveolar or glandular type with an irregular basal membrane and loose position of cells. The primary histological diagnosis suggested a tumor of mesenchymal origin. Followed by immunomorphologic (monoclonal antibody to KL 1) and electron-microscopic examinations, the diagnosis was verified providing evidence for epithelial nature of the tumor cells, loose, forming glandular-like structures and simulating stromal elements with ultrastructural features typical of myoepithelial differentiation. The evidence obtained justify the tumor definition as a rare neoplasm of the breast known in the literature as myoepithelioma.
authors.forename: V D
authors.initials: VD
authors.lastname: Ermilova
authors.forename: T I
authors.initials: TI
authors.lastname: Kondakova
authors.forename: N A
authors.initials: NA
authors.lastname: Filippova
authors.forename: V I
authors.initials: VI
authors.lastname: Gel'shteĭn
authors.forename: T A
authors.initials: TA
authors.lastname: Chipysheva
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008854:Microscopy, Electron; D008875:Middle Aged; D009208:Myoepithelioma / Q000473:pathology* / Q000648:ultrastructure
vernacular_title: Zlokachestvennaia mioépitelioma molochnoĭ zhelezy (gistologicheskoe,immunomorphologicheskoe issledovanie)