title: Occurrence of P-fimbriated Escherichia coli in patients with bacteremia.
abstract: The case history of 88 patients with blood cultures positive for Escherichia coli and evidence of systemic disease was reviewed, and the Escherichia coli blood isolates tested for P-fimbriation. Fifty-five strains (63%) were P-fimbriated. Patients with a positive urine culture had a higher incidence of P-fimbriated Escherichia coli strains (53/75, 71%) than patients with a negative urine culture (2/13, 15%). Patients with no predisposing factors, such as instrumentation of the urinary tract or a chronic disease, had a significantly higher frequency of P-fimbriated strains (31/36, 86%) compared to patients without such underlying factors (p less than 0.01). There was no significant difference in clinical parameters or in frequency of P-fimbriated strains between patients with one positive blood culture and those with two or more positive cultures. The high incidence of P-fimbriated Escherichia coli strains in these patients is thought to depend on the ability of such bacteria to cause acute pyelonephritis, which in many cases precedes Escherichia coli bacteremia.
authors.forename: A
authors.initials: A
authors.lastname: Brauner
authors.forename: M
authors.initials: M
authors.lastname: Leissner
authors.forename: B
authors.initials: B
authors.lastname: Wretlind
authors.forename: I
authors.initials: I
authors.lastname: Julander
authors.forename: S B
authors.initials: SB
authors.lastname: Svenson
authors.forename: G
authors.initials: G
authors.lastname: Källenius
mesh_terms: D000268:Adhesiveness; D000372:Agglutination Tests; D004926:Escherichia coli / Q000648:ultrastructure*; D004927:Escherichia coli Infections / Q000382:microbiology*; D005243:Feces / Q000382:microbiology; D005260:Female; D010861:Fimbriae, Bacterial / Q000032:analysis*; D006801:Humans; D008297:Male; D010127:P Blood-Group System; D011704:Pyelonephritis / Q000209:etiology / Q000382:microbiology; D018805:Sepsis / Q000209:etiology / Q000382:microbiology*
chemical_list: D010127:P Blood-Group System