title: Leukotriene release by human fetal membranes, placenta and decidua in relation to parturition.
abstract: Complete placentas and membranes were obtained from women after uncomplicated singleton pregnancies. Six were collected after labour at term, six after preterm labour and six after elective Caesarean section at term. Leukotriene C4 (LTC4), leukotriene D4 (LTD4) and leukotriene E4 (LTE4) release was examined using a short-term incubation technique. Release by amnion was significantly higher than that by the other tissues for the three modes of delivery. Comparison of LTC4, LTD4 and LTE4 release by individual tissues with regard to the type of delivery showed no significant difference.
authors.affiliation: Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Oxford.
authors.forename: M C
authors.initials: MC
authors.lastname: Rees
authors.forename: V
authors.initials: V
authors.lastname: Di Marzo
authors.forename: A
authors.initials: A
authors.lastname: Lopez Bernal
authors.forename: J R
authors.initials: JR
authors.lastname: Tippins
authors.forename: H R
authors.initials: HR
authors.lastname: Morris
authors.forename: A C
authors.initials: AC
authors.lastname: Trunbull
mesh_terms: D002585:Cesarean Section; D003656:Decidua / Q000378:metabolism*; D005321:Extraembryonic Membranes / Q000378:metabolism*; D005260:Female; D006801:Humans; D007743:Labor, Obstetric / Q000378:metabolism*; D017999:Leukotriene E4; D015289:Leukotrienes / Q000378:metabolism*; D007752:Obstetric Labor, Premature / Q000378:metabolism; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy; D013189:SRS-A / Q000031:analogs & derivatives / Q000378:metabolism
chemical_list: D015289:Leukotrienes; D013189:SRS-A; D017999:Leukotriene E4