title: Angina: current approaches to diagnosis, drug therapy, and surgical referral.
abstract: An abnormal resting ST segment renders the stress ECG impossible to interpret. Therefore, one must substitute a radionuclide stress evaluation in the presence of digitalis, left bundle-branch block, left ventricular hypertrophy, a paced rhythm, or any other condition that would cause abnormal baseline ST segments. All these are more common in the elderly. Beta-blocker therapy is useful in patients with demand-related ischemia because it decreases two of the major determinants of myocardial oxygen demand: heart rate and contractility. Propranolol, timolol, and metoprolol have been shown to decrease the reinfarction and mortality rates in patients who have had an infarction.
authors.forename: D G
authors.initials: DG
authors.lastname: Renlund
authors.forename: G
authors.initials: G
authors.lastname: Gerstenblith
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000368:Aged; D000375:Aging; D000787:Angina Pectoris / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D000800:Angioplasty, Balloon; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D006328:Cardiac Catheterization; D002302:Cardiac Output; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology; D004562:Electrocardiography; D005080:Exercise Test; D006339:Heart Rate; D006801:Humans; D008875:Middle Aged; D005996:Nitroglycerin / Q000627:therapeutic use; D010808:Physical Examination
chemical_list: D000319:Adrenergic beta-Antagonists; D002121:Calcium Channel Blockers; D005996:Nitroglycerin