title: [Local recurrent centroblastic lymphoma of the skin].
abstract: A 57-year-old patient suffered from a cutaneous centroblastic polymorphic non-Hodgkin lymphoma. This tumour first occurred 6 years ago and showed local relapses after two surgical excisions without any internal manifestations. The tumour had unusual morphological features with a sarcomatous growth pattern and numerous multilobated nuclei, which first led to the diagnosis of a malignant fibrous histiocytoma. Additional immunohistological studies of both the primary tumour and the lesions demonstrated the presence of lymphocytic marker proteins and allowed the definitive classifications as a high-grade malignant non-Hodgkin lymphoma of the B-cell type.
authors.affiliation: Dermatologische Klinik und Poliklinik, Ludwig-Maximilians-Universität München.
authors.forename: F
authors.initials: F
authors.lastname: Eckert
authors.forename: R
authors.initials: R
authors.lastname: Hein
authors.forename: T
authors.initials: T
authors.lastname: Krieg
authors.forename: G
authors.initials: G
authors.lastname: Burg
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D003937:Diagnosis, Differential; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology; D006801:Humans; D007124:Immunoenzyme Techniques; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor
vernacular_title: Lokal rezidivierendes zentroblastisches Lymphom der Haut.