Distribution and excretion of 3H-dapiprazole in the rat.
Tissue distribution as well as biliary, urinary and fecal excretion of 3H-dapiprazole was studied in the rat. The product is found in many tissues, including the brain. About 23 and 57% of the dose is excreted in the urine and feces and about 65% is eliminated in the bile.
Valeri
P
P
Palmery
M
M
Catanese
B
B
D000818:Animals; D014150:Antipsychotic Agents / Q000378:metabolism* / Q000652:urine; D001646:Bile / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D005243:Feces / Q000032:analysis; D005260:Female; D008297:Male; D010879:Piperazines; D051381:Rats; D013997:Time Factors; D014018:Tissue Distribution; D014230:Triazoles / Q000378:metabolism* / Q000652:urine
D014150:Antipsychotic Agents; D010879:Piperazines; D014230:Triazoles; C035289:dapiprazole