title: Antigenic and genetic properties of viruses linked to hemorrhagic fever with renal syndrome.
abstract: Hemorrhagic fever with renal syndrome (HFRS) comprises a variety of clinically similar diseases of viral etiology that are endemic to and sporadically epidemic throughout the Eurasian continent and Japan. Although HFRS has not been reported in North America, viruses that are antigenically similar to HFRS agents were recently isolated from rodents in the United States. Examination and comparison of eight representative isolates from endemic disease areas and from regions with no known associated HFRS indicate that these viruses represent a new and unique group that constitutes a separate genus in the Bunyaviridae family of animal viruses.
authors.forename: C S
authors.initials: CS
authors.lastname: Schmaljohn
authors.forename: S E
authors.initials: SE
authors.lastname: Hasty
authors.forename: J M
authors.initials: JM
authors.lastname: Dalrymple
authors.forename: J W
authors.initials: JW
authors.lastname: LeDuc
authors.forename: H W
authors.initials: HW
authors.lastname: Lee
authors.forename: C H
authors.initials: CH
authors.lastname: von Bonsdorff
authors.forename: M
authors.initials: M
authors.lastname: Brummer-Korvenkontio
authors.forename: A
authors.initials: A
authors.lastname: Vaheri
authors.forename: T F
authors.initials: TF
authors.lastname: Tsai
authors.forename: H L
authors.initials: HL
authors.lastname: Regnery
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000276:immunology; D003411:Arvicolinae; D001483:Base Sequence; D002043:Bunyaviridae / Q000235:genetics; D006476:Orthohantavirus / Q000235:genetics / Q000276:immunology*; D006480:Hemorrhagic Fever with Renal Syndrome / Q000235:genetics / Q000276:immunology / Q000382:microbiology*; D006801:Humans; D007723:Korea; D051379:Mice; D009115:Muridae; D009500:Neutralization Tests; D012328:RNA Viruses / Q000276:immunology*; D011863:Radioimmunoassay; D051381:Rats; D011919:Rats, Inbred Strains; D014481:United States
chemical_list: D000956:Antigens, Viral