title: Solitary cutaneous reticulum cell tumor. Enzyme-immunohistochemical and electron-microscopic analogies with IDRC sarcoma.
abstract: We herein report a case of solitary cutaneous reticulum cell tumor not associated with any other organ involvement. The enzyme-immunohistochemical and electron-microscopic features of the cellular infiltrate are the same as those of interdigitating reticulum cells (IDRC), which can give rise to neoplasms in lymphoid organs; they are also similar to those of Langerhans cells and "indeterminate" cells, which are usually thought to give rise only to systemic disorders. The authors support the hypothesis that such neoplasms may represent the cutaneous counterpart of IDRC neoplasms of lymphoid organs.
authors.affiliation: Institute of Pathological Anatomy and Histology, University of Siena, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Miracco
authors.forename: M
authors.initials: M
authors.lastname: Raffaelli
authors.forename: M M
authors.initials: MM
authors.lastname: de Santi
authors.forename: M
authors.initials: M
authors.lastname: Fimiani
authors.forename: P
authors.initials: P
authors.lastname: Tosi
mesh_terms: D000293:Adolescent; D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D016403:Lymphoma, Large B-Cell, Diffuse / Q000201:enzymology / Q000473:pathology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D009364:Neoplasm Recurrence, Local; D015388:Organelles / Q000648:ultrastructure; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism; D012878:Skin Neoplasms / Q000201:enzymology / Q000473:pathology* / Q000648:ultrastructure; D013848:Thigh
chemical_list: D010744:Phosphoric Monoester Hydrolases