title: Compressive properties of polymer coated synthetic hydroxyapatite for bone grafting.
abstract: A porous hydroxyapatite material hydrothermally converted from the calcium carbonate exoskeleton of the coral, genus Goniopora (CHAG) was either microcoated using polymethylmethacrylate (PMMA) or polylactic acid (PLA) to cover all internal surfaces, or externally coated to produce a shell, with the objective of reducing the brittleness of the material. Compressive testing showed that while CHAG, externally coated with PMMA, showed the largest increases in strength, stiffness, and energy absorption, the uncoated hydroxyapatite core cracked at low loads although the shell remained intact. CHAG internally microcoated with PMMA showed a 3.84 increase in compressive strength while specimens with internal PLA coatings had 1.81 times the compressive strength of uncoated CHAG specimens. Compared to the mechanical properties of cancellous graft material, specimens internally microcoated with either polymer could be produced having properties equivalent to or greater than those of cancellous graft.
authors.affiliation: Biomedical Engineering Program, University of Texas, Arlington 76019.
authors.forename: A F
authors.initials: AF
authors.lastname: Tencer
authors.forename: V
authors.initials: V
authors.lastname: Mooney
authors.forename: K L
authors.initials: KL
authors.lastname: Brown
authors.forename: P A
authors.initials: PA
authors.lastname: Silva
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001842:Bone and Bones / Q000601:surgery; D004285:Dogs; D017886:Durapatite; D006882:Hydroxyapatites; D007773:Lactates; D019344:Lactic Acid; D008422:Materials Testing; D008768:Methylmethacrylates; D011091:Polyesters; D011108:Polymers; D011312:Pressure; D019736:Prostheses and Implants
chemical_list: D001672:Biocompatible Materials; D006882:Hydroxyapatites; D007773:Lactates; D008768:Methylmethacrylates; D011091:Polyesters; D011108:Polymers; D019344:Lactic Acid; C033616:poly(lactide); D017886:Durapatite