Detection of cytomegalovirus in clinical specimens using shell vial centrifugation and conventional cell culture.
Shell vial centrifugation and conventional cell culture methods for detecting cytomegalovirus (CMV) were compared in clinical specimens. Our data confirm that the shell vial centrifugation method is more sensitive and rapid than conventional cell culture; however, due to the shell vial method's problems with toxicity to the fibroblast monolayer, both methods must be performed if all specimens positive for CMV are to be detected.
Forbes
B A
BA
Division of Clinical Pathology, State University of New York, Syracuse 13210.
Bartholoma
N Y
NY
D003587:Cytomegalovirus / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D014776:Virus Cultivation / Q000379:methods