[Clinical use of IM-PH immuno-columns].
The results of plasma perfusion through immunoabsorbent columns were assessed in neuroimmunological conditions. The method is a modified plasmapheresis. The plasma is passed through a column of polyvinyl alcohol gel bound with phenylalanine. Three patients were treated by this method (two with acute polyneuropathies due to the Guillain-Barré syndrome, and the third with a polyneuropathy related to Hepatitis A). Each patient underwent 3 sessions, on alternate days for a six day period, with perfusion of 6-6.5 1 of plasma. No adverse effects were observed during treatment or changes in PAO values. Serum Na+-K+-Cl-Ca++-Gluc-Tot Prot-Alb-RBC-WBC-Hb-Urea and Creatinine were constant. Complete remission of the peripheral symptoms of the patients with the Guillain-Barré syndrome was observed whilst the third patient had a partial remission (in the left arm). These observations suggest that this method may be of therapeutic value in patients with acute polyneuropathy due to the Guillain-Barré syndrome.
Maresca
M C
MC
Services de Néphrologie et de Neurologie, Hôpital de Trévise, Italie.
Da Porto
A
A
Cusumano
S
S
Serena
M
M
D000328:Adult; D005260:Female; D006506:Hepatitis A / Q000150:complications; D006801:Humans; D007163:Immunosorbent Techniques / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged; D010477:Perfusion; D010523:Peripheral Nervous System Diseases / Q000209:etiology / Q000628:therapy*; D010956:Plasmapheresis / Q000295:instrumentation* / Q000379:methods; D011129:Polyradiculoneuropathy / Q000628:therapy*
Application clinique de l'immuno-colonne IM-PH.