Complete complementary DNA of rat tyrosine aminotransferase messenger RNA. Deduction of the primary structure of the enzyme.
The primary structure of rat tyrosine aminotransferase (L-tyrosine:2-oxoglutarate aminotransferase; EC 2.6.1.5), a liver-specific enzyme involved in gluconeogenesis, has been deduced from the nucleotide sequence of a cloned full-length cDNA. The mRNA is 2362 nucleotides long (excluding the poly(A) tail) and codes for a polypeptide of 454 amino acids with a molecular weight of 50634. Unambiguous identification was obtained by comparison of this sequence with the amino acid sequences of several peptides obtained from the purified enzyme.
Grange
T
T
Guénet
C
C
Dietrich
J B
JB
Chasserot
S
S
Fromont
M
M
Befort
N
N
Jami
J
J
Beck
G
G
Pictet
R
R
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics*; D051381:Rats; D014444:Tyrosine Transaminase / Q000235:genetics*
D012333:RNA, Messenger; D004247:DNA; D014444:Tyrosine Transaminase