title: [Visceral leishmaniasis (kala-azar) in acquired immunodeficiency syndrome (AIDS)].
abstract: A 32-year-old homosexual with AIDS, who until 1985 was a frequent traveller to South America and mediterranean countries, had recurrent bouts of fever, splenomegaly, arthralgias as well as granulocytopenia and anaemia. Liver and bone-marrow punctures were performed to exclude malignant lymphoma and (or) a mycobacterial infection. Both biopsies revealed Leishmania donovani. During administration of sodium stibogluconate (Pentostam) the fever disappeared for a time and there was clinical improvement, but further treatment was limited because of thrombocytopenia. In patients with AIDS who have splenomegaly with nonspecific fever, visceral leishmaniasis must be considered in the differential diagnosis even outside of endemic regions.
authors.affiliation: Zentrum der Inneren Medizin, Universität Frankfurt/Main.
authors.forename: G
authors.initials: G
authors.lastname: Just
authors.forename: R
authors.initials: R
authors.lastname: Simader
authors.forename: E B
authors.initials: EB
authors.lastname: Helm
authors.forename: W
authors.initials: W
authors.lastname: Stille
authors.forename: S
authors.initials: S
authors.lastname: Falk
authors.forename: H J
authors.initials: HJ
authors.lastname: Stutte
authors.forename: K
authors.initials: K
authors.lastname: Hübner
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D000967:Antimony Sodium Gluconate / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006801:Humans; D007898:Leishmaniasis, Visceral / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D008297:Male; D013020:South America; D014195:Travel
chemical_list: D000967:Antimony Sodium Gluconate
vernacular_title: Viszerale Leishmaniose (Kala-Azar) bei erworbenem Immundefektsyndrom (AIDS).