Neurohumoral interactions in the posttraumatic period and possibilities of their correction.
Changes of neuromediators and their correction in the posttraumatic period after acute blood loss were studied experimentally in mongrel dogs. Survival of white rats was examined after heavy combined trauma during therapeutic use of exogenous cholinesterase and serotonin. Their use was studied clinically in patients with heavy combined trauma. The use of exogenous cholinesterase and serotonin in a complex of resuscitation measures permits stabilization of the functional state of the adrenal cortex and the cholinergic, adrenergic and serotoninergic systems.
Bazarevitch
G J
GJ
Beilin
M A
MA
Lazareva
L V
LV
D000109:Acetylcholine / Q000097:blood; D000110:Acetylcholinesterase / Q000097:blood; D000302:Adrenal Cortex / Q000187:drug effects; D000818:Animals; D002395:Catecholamines / Q000097:blood; D002802:Cholinesterases / Q000097:blood / Q000627:therapeutic use*; D004285:Dogs; D006801:Humans; D008995:Monoamine Oxidase / Q000097:blood; D018377:Neurotransmitter Agents / Q000097:blood*; D010275:Parasympathetic Nervous System / Q000187:drug effects; D051381:Rats; D012151:Resuscitation; D012701:Serotonin / Q000097:blood / Q000627:therapeutic use*; D013564:Sympathetic Nervous System / Q000187:drug effects; D014947:Wounds and Injuries / Q000097:blood* / Q000628:therapy
D002395:Catecholamines; D018377:Neurotransmitter Agents; D012701:Serotonin; D008995:Monoamine Oxidase; D000110:Acetylcholinesterase; D002802:Cholinesterases; D000109:Acetylcholine