title: Rapid tranquilization: the efficacy of oral concentrate.
abstract: The efficacy of oral concentrate in the rapid tranquilization of 159 acutely disturbed patients in a psychiatric emergency service was evaluated. Patients were randomly assigned to 1 of 10 treatment groups: 7 oral groups and 3 comparison intramuscular groups. Although intramuscular medication produced a faster response, concentrate also proved to be effective for rapid tranquilization. Side effects were benign and minimal. Age, sex, race, and diagnosis had no effect on outcome. The use of concentrate as a paradigm for treating acutely psychotic patients is discussed.
authors.forename: W R
authors.initials: WR
authors.lastname: Dubin
authors.forename: H M
authors.initials: HM
authors.lastname: Waxman
authors.forename: K J
authors.initials: KJ
authors.lastname: Weiss
authors.forename: D
authors.initials: D
authors.lastname: Ramchandani
authors.forename: C
authors.initials: C
authors.lastname: Tavani-Petrone
mesh_terms: D000208:Acute Disease; D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D014150:Antipsychotic Agents / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D004637:Emergency Services, Psychiatric; D005260:Female; D006220:Haloperidol / Q000008:administration & dosage; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000188:drug therapy* / Q000523:psychology; D013881:Thioridazine / Q000008:administration & dosage; D013888:Thiothixene / Q000008:administration & dosage; D013997:Time Factors
chemical_list: D014150:Antipsychotic Agents; D013888:Thiothixene; D006220:Haloperidol; D013881:Thioridazine