title: Immunohistochemical demonstration of catecholaminergic cell bodies in the spinal cord of the rat. Preliminary note.
abstract: In order to elucidate the anatomy of the spinal dopaminergic system, an immunohistochemical study using a tyrosine-hydroxylase (TH) antibody was undertaken in the rat. Intracisternal 6-hydroxydopamine (6-OHDA) injections were administered to destroy most of the noradrenergic fibres that descend to the spinal cord while preserving the dopaminergic fibres. The density of the remaining TH-like immunoreactive fibres was relatively low at all levels of the spinal cord; the highest density was observed in layers III, IV and X. In addition, we report the first evidence for the existence of TH-like immunoreactive cell bodies at definite levels (especially sacral) of the spinal cord.
authors.forename: M
authors.initials: M
authors.lastname: Dietl
authors.forename: M
authors.initials: M
authors.lastname: Arluison
authors.forename: P
authors.initials: P
authors.lastname: Mouchet
authors.forename: C
authors.initials: C
authors.lastname: Feuerstein
authors.forename: M
authors.initials: M
authors.lastname: Manier
authors.forename: J
authors.initials: J
authors.lastname: Thibault
mesh_terms: D000818:Animals; D002395:Catecholamines / Q000032:analysis*; D006892:Hydroxydopamines / Q000494:pharmacology; D007124:Immunoenzyme Techniques; D008297:Male; D009412:Nerve Fibers / Q000201:enzymology*; D016627:Oxidopamine; D051381:Rats; D011919:Rats, Inbred Strains; D013116:Spinal Cord / Q000166:cytology* / Q000201:enzymology; D014446:Tyrosine 3-Monooxygenase / Q000032:analysis / Q000276:immunology
chemical_list: D002395:Catecholamines; D006892:Hydroxydopamines; D016627:Oxidopamine; D014446:Tyrosine 3-Monooxygenase