title: [Cyclic nucleotides in experimental glaucoma].
abstract: cAMP and cGMP contents were studied in various eye tissues of rabbits with experimental glaucoma induced by chronic intravenous adrenaline administration. Cyclic nucleotide level was measured in the retina, choroid, iris and ciliary body. An increase in the tissue cAMP level was found especially in the iris and ciliary body. An increase in tissue cAMP content is explained by an enhanced beta-adrenergic regulation in the eyes of rabbits with experimental glaucoma. No consistent changes were found in cGMP content in eye tissues.
authors.forename: G N
authors.initials: GN
authors.lastname: Kryshanowskiĭ
authors.forename: L T
authors.initials: LT
authors.lastname: Kashintseva
authors.forename: I N
authors.initials: IN
authors.lastname: Mikheĭtseva
authors.forename: E M
authors.initials: EM
authors.lastname: Lipovetskaia
authors.forename: O P
authors.initials: OP
authors.lastname: Kopp
mesh_terms: D000818:Animals; D002829:Choroid / Q000032:analysis; D002924:Ciliary Body / Q000032:analysis; D000242:Cyclic AMP / Q000032:analysis*; D006152:Cyclic GMP / Q000032:analysis*; D004837:Epinephrine; D005123:Eye / Q000032:analysis*; D005901:Glaucoma / Q000139:chemically induced / Q000378:metabolism* / Q000503:physiopathology; D007498:Iris / Q000032:analysis; D011817:Rabbits; D011943:Receptors, Adrenergic, beta / Q000503:physiopathology; D012160:Retina / Q000032:analysis
chemical_list: D011943:Receptors, Adrenergic, beta; D000242:Cyclic AMP; D006152:Cyclic GMP; D004837:Epinephrine
vernacular_title: Tsiklicheskie nukleotidy pri éksperimental'noĭ glaukome.