Quantitative and qualitative biochemical parameters for alcohol abuse.
Blood from alcoholics, non-alcoholic patients and healthy controls were analyzed for various biochemical markers. Follow-up measurements were made during about 3 months of abstention. While a gradual increase in aldehyde dehydrogenase activity (ALDH) in red cell was noted in alcoholic patients serum alpha 1-acid glycoprotein (AAG) values returned to normal range within 8 weeks during abstinence. An additional minor band for alpha 1-antitrypsin (AAT) was observed after isoelectric focusing of sera from alcoholics; this band disappeared after 3 weeks of abstinence. However, no such unusual AAT band was found in non-alcoholic patients with liver disorders.
Harada
S
S
Agarwal
D P
DP
Goedde
H W
HW
Miyake
K
K
D000410:Alanine Transaminase / Q000097:blood; D000437:Alcoholism / Q000097:blood*; D000444:Aldehyde Dehydrogenase / Q000097:blood; D004912:Erythrocytes / Q000201:enzymology; D006801:Humans; D007525:Isoelectric Focusing; D007527:Isoenzymes / Q000097:blood; D009961:Orosomucoid / Q000097:blood; D000515:alpha 1-Antitrypsin / Q000097:blood; D005723:gamma-Glutamyltransferase / Q000097:blood
D007527:Isoenzymes; D009961:Orosomucoid; D000515:alpha 1-Antitrypsin; D000444:Aldehyde Dehydrogenase; D005723:gamma-Glutamyltransferase; D000410:Alanine Transaminase