[The role of the beta-adrenoreceptors in the smooth-muscle reactions of the stomach, pyloric sphincter and duodenum to serotonin administration].
Subcutaneous administration of serotonin (10 mg/kg) altered myoelectrical activity of the stomach, pylorus and duodenum in rabbits causing a discoordination of gastroduodenal motor activity. During activation of beta-Adrenoceptors serotonin induced discoordination superimposed on disturbance of normal coordination of the stomach, pylorus and duodenum induced with isopropylnoradrenaline. beta-Adrenoceptor blockade decreased the degree of serotonin-induced discoordination between motility of the stomach and duodenum as concerns the rhythmic component of their activity.
Shemerovskiĭ
K A
KA
Ovsiannikov
V I
VI
D000818:Animals; D004386:Duodenum / Q000187:drug effects / Q000502:physiology; D004576:Electromyography; D004594:Electrophysiology; D007545:Isoproterenol / Q000494:pharmacology; D009130:Muscle, Smooth / Q000187:drug effects* / Q000502:physiology; D011433:Propranolol / Q000494:pharmacology; D011708:Pylorus / Q000187:drug effects / Q000502:physiology; D011817:Rabbits; D011943:Receptors, Adrenergic, beta / Q000187:drug effects* / Q000502:physiology; D012701:Serotonin / Q000494:pharmacology*; D013270:Stomach / Q000187:drug effects / Q000502:physiology
D011943:Receptors, Adrenergic, beta; D012701:Serotonin; D011433:Propranolol; D007545:Isoproterenol
Rol' beta-adrenoretseptorov v reaktsiiakh gladkikh myshts zheludka, piloricheskogo sfinktera i dvenadtsatiperstnoĭ kishki na vvedenie serotonina.