title: Na+-independent L-aspartate binding sites in chick brain.
abstract: 1. One binding component with a Kd value of 200 x 10(-9) M and half-life of the ligand binding component of 30 min was found. 2. Chloride ions produced a significant increase of L-[3H]aspartate and L-[3H]glutamate binding. 3. L-Glutamate, L-ibotenate, L-quisqualate, and DL-homocysteic acid were potent inhibitors of L-[3H]aspartate binding. 4. In all brain regions major increases of binding were observed during the third week of the in ovo period of life.
authors.affiliation: Department of Physiology, School of Medicine, University of Patras, Greece.
authors.forename: G
authors.initials: G
authors.lastname: Voukelatou
authors.forename: E D
authors.initials: ED
authors.lastname: Kouvelas
mesh_terms: D000375:Aging / Q000378:metabolism*; D000818:Animals; D001667:Binding, Competitive; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D002645:Chickens / Q000378:metabolism*; D007700:Kinetics; D017459:Receptors, Amino Acid; D011956:Receptors, Cell Surface / Q000187:drug effects / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism*; D013696:Temperature
chemical_list: D017459:Receptors, Amino Acid; D011956:Receptors, Cell Surface; C031959:aspartic acid receptor; D012964:Sodium