title: [Effect of cyclic 3,5-adenosine monophosphate on the virulence of Salmonella typhimurium].
abstract: To study the role of cAMP in the virulence of S. typhimurium, cAMP-producing plasmid pTG 4 was transferred to cAMP-deficient S. typhimurium mutant. The transfer of the plasmid enhanced the virulence of the microorganisms due to the increased destruction of macrophages and the intensified multiplication of salmonellae in the spleen of mice.
authors.forename: M N
authors.initials: MN
authors.lastname: Boĭchenko
authors.forename: A M
authors.initials: AM
authors.lastname: Dombrovskiĭ
authors.forename: I G
authors.initials: IG
authors.lastname: Sivov
mesh_terms: D000818:Animals; D000242:Cyclic AMP / Q000502:physiology*; D008264:Macrophages / Q000502:physiology; D051379:Mice; D012486:Salmonella typhimurium / Q000472:pathogenicity*; D014774:Virulence
chemical_list: D000242:Cyclic AMP
vernacular_title: Vliianie tsiklicheskogo 3,5-adenozin-monofosfata na virulentnost' Salmonella typhimurium.