title: Acute schizophrenia.
abstract: The antipsychotic effect of neuroleptics appears to depend upon dopaminergic blockade. Neither prolactin nor drug levels are helpful in the clinical situation. The value of neuroleptics both as an acute treatment for schizophrenic episodes and as a prophylactic against relapse is undoubted but even with assured compliance, these drugs cannot be considered as curative and the prognosis is often limited.
authors.forename: E C
authors.initials: EC
authors.lastname: Johnstone
mesh_terms: D000208:Acute Disease; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000378:metabolism / Q000627:therapeutic use*; D005475:Flupenthixol / Q000627:therapeutic use; D006801:Humans; D007700:Kinetics; D011388:Prolactin / Q000097:blood; D012008:Recurrence; D012559:Schizophrenia / Q000188:drug therapy* / Q000378:metabolism / Q000517:prevention & control
chemical_list: D014150:Antipsychotic Agents; D011388:Prolactin; D005475:Flupenthixol