Foscarnet as treatment for cytomegalovirus retinitis following bone marrow transplantation.
This report describes a patient with chronic granulocytic leukaemia who developed cataracts on busulphan treatment. Following allogeneic bone marrow transplantation, he developed cytomegalovirus retinitis, which was treated successfully with trisodium phosphonoformate (foscarnet). Cytomegalovirus retinitis and its therapy, and busulphan-induced cataract are discussed.
Ganly
P S
PS
Department of Haematology, Hammersmith Hospital, London, UK.
Arthur
C
C
Goldman
J M
JM
Schulenburg
W E
WE
D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use*; D016026:Bone Marrow Transplantation; D002066:Busulfan / Q000009:adverse effects; D002386:Cataract / Q000139:chemically induced; D003586:Cytomegalovirus Infections / Q000188:drug therapy*; D017245:Foscarnet; D006801:Humans; D007165:Immunosuppression Therapy; D008297:Male; D009943:Organophosphorus Compounds / Q000627:therapeutic use*; D010746:Phosphonoacetic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use*; D012173:Retinitis / Q000188:drug therapy*
D000998:Antiviral Agents; D009943:Organophosphorus Compounds; D017245:Foscarnet; D002066:Busulfan; D010746:Phosphonoacetic Acid