Increased risk of cervical neoplasia in consorts of men with penile condylomata acuminata.
19 (76%) of 25 women who had been the sole sexual consorts, for at least 1 year, of men with pre-existing penile condylomata acuminata had similar lesions of the lower genital tract. 9 (36%) of the women had an abnormal cervix as judged by cytology, colposcopy, and histology, and 7 (77%) of these 9 had associated human papillomavirus (HPV) infection detected by DNA/DNA hybridisation. None of 20 women in an age-matched control group had cytological or colposcopic evidence of cervical epithelial atypia. It is suggested that penile HPV infection in a male partner places a woman at risk of cervical neoplasia.
Campion
M J
MJ
Singer
A
A
Clarkson
P K
PK
McCance
D J
DJ
D000328:Adult; D000818:Animals; D003075:Coitus; D003218:Condylomata Acuminata / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D009693:Nucleic Acid Hybridization; D027383:Papillomaviridae; D010412:Penile Neoplasms / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D012306:Risk; D014412:Tumor Virus Infections / Q000382:microbiology / Q000473:pathology / Q000635:transmission*; D002583:Uterine Cervical Neoplasms / Q000209:etiology* / Q000382:microbiology / Q000473:pathology