title: Immunobiology of the expanded T cells in T-cell leukemia and T-gamma lymphocytosis.
abstract: A review is presented of functional studies performed with the expanded T cells in Sézary syndrome, T-cell chronic lymphocytic leukemia (T-CLL), T-prolymphocytic leukemia (T-PLL), adult T-cell leukemia lymphoma (ATLL), T-cell acute lymphoblastic leukemia (T-ALL) and T gamma lymphocytosis. The immunological and clinical relevance of immunological studies of functional properties of T-cell expansions is discussed.
authors.forename: F
authors.initials: F
authors.lastname: Miedema
authors.forename: C J
authors.initials: CJ
authors.lastname: Melief
mesh_terms: D006800:Deltaretrovirus Infections / Q000276:immunology*; D006801:Humans; D007136:Immunoglobulins / Q000096:biosynthesis; D007376:Interleukin-2 / Q000096:biosynthesis; D007694:Killer Cells, Natural / Q000276:immunology; D008218:Lymphocytosis / Q000276:immunology*; D011948:Receptors, Antigen, T-Cell / Q000235:genetics; D011961:Receptors, Fc / Q000032:analysis; D011995:Recombination, Genetic; D012751:Sezary Syndrome / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
chemical_list: D007136:Immunoglobulins; D007376:Interleukin-2; D011948:Receptors, Antigen, T-Cell; D011961:Receptors, Fc