title: Use of monophasic action potential recordings during routine coronary-artery bypass surgery as an index of localised myocardial ischaemia.
abstract: In 8 patients undergoing routine coronary-artery bypass surgery, monophasic action potentials (MAPs) were measured by means of a hand-held pressure contact electrode to provide an index of local ischaemic changes. 4 patients received left internal mammary anastomoses (LIMA), and there were a total of 27 saphenous vein grafts (SVG). After completion of all grafts blood-flow to the myocardium was reduced for 90 s by means of different permutations of SVG and LIMA occlusion, either on or off bypass. In all patients MAPs indicated typical ischaemic changes. The high sensitivity of the method enables the study to be completed quickly and without hazard to the patient. The technique provides a new means to assess local ischaemia, the viability of specific areas of myocardium, and the efficiency of individual grafts during surgery.
authors.forename: P
authors.initials: P
authors.lastname: Taggart
authors.forename: P
authors.initials: P
authors.lastname: Sutton
authors.forename: M
authors.initials: M
authors.lastname: Runnalls
authors.forename: W
authors.initials: W
authors.lastname: O'Brien
authors.forename: R
authors.initials: R
authors.lastname: Donaldson
authors.forename: R
authors.initials: R
authors.lastname: Hayward
authors.forename: H
authors.initials: H
authors.lastname: Swanton
authors.forename: R
authors.initials: R
authors.lastname: Emanuel
authors.forename: T
authors.initials: T
authors.lastname: Treasure
mesh_terms: D000200:Action Potentials; D000328:Adult; D000368:Aged; D001026:Coronary Artery Bypass; D003326:Coronary Circulation; D003327:Coronary Disease / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007430:Intraoperative Care; D008297:Male; D008839:Microelectrodes; D008875:Middle Aged; D010496:Pericardium / Q000503:physiopathology*