title: Barrett's oesophagus and colonic tumours.
abstract: Of 65 patients with Barrett's oesophagus, all of whom were white, 29 (44.6%) had colonic tumours; 19 were benign and 10 were malignant. The frequency of colonic cancer was especially high (38%) in patients with Barrett's oesophagus aged 64 years or older. 7 of the 65 patients had had previous colonic resections for cancer and 3 were found prospectively to have malignant tumours. Benign tumours had been removed by colonoscopic polypectomy in 3 of the 19 patients; in 16 patients the tumours were diagnosed prospectively. In comparison with two other high risk groups, malignant tumours were found in 7.7% of 325 symptomatic patients admitted for colonoscopy and in 11.3% of 120 symptom-free patients with occult blood in the stools. The probability of finding this number of malignant tumours in an age-matched random sample of the general population is less than one in a million.
authors.forename: S J
authors.initials: SJ
authors.lastname: Sontag
authors.forename: T G
authors.initials: TG
authors.lastname: Schnell
authors.forename: G
authors.initials: G
authors.lastname: Chejfec
authors.forename: S
authors.initials: S
authors.lastname: O'Connell
authors.forename: M M
authors.initials: MM
authors.lastname: Stanley
authors.forename: W
authors.initials: W
authors.lastname: Best
authors.forename: R
authors.initials: R
authors.lastname: Chintam
authors.forename: B
authors.initials: B
authors.lastname: Nemchausky
authors.forename: J
authors.initials: J
authors.lastname: Wanner
authors.forename: B
authors.initials: B
authors.lastname: Moroni
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology; D000328:Adult; D000368:Aged; D001471:Barrett Esophagus / Q000150:complications* / Q000473:pathology; D003110:Colonic Neoplasms / Q000150:complications* / Q000473:pathology; D003113:Colonoscopy; D004935:Esophageal Diseases / Q000150:complications*; D004947:Esophagus / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged