title: [Rhinomanometric measurements following intranasal allergen provocation].
abstract: Intranasal provocation tests followed by rhinomanometry were performed on 49 males with defined pollen allergy. Subsequently each patient took two tablets of tritoqualine, 100 mg each, three times daily for four or five days. Intranasal provocation was then repeated with the same allergen and flow again measured by rhinomanometry. There was a highly significant, treatment-induced rise in breath-flow through both nasal passages. The drug was well tolerated and no side effects, in particular no sedative action, were observed.
authors.forename: H
authors.initials: H
authors.lastname: Gastpar
authors.forename: P H
authors.initials: PH
authors.lastname: Sauer
mesh_terms: D006634:Histamine H1 Antagonists / Q000627:therapeutic use*; D006801:Humans; D007546:Isoquinolines / Q000627:therapeutic use*; D008297:Male; D008365:Manometry / Q000379:methods; D009299:Nasal Provocation Tests; D011058:Pollen; D012123:Pulmonary Ventilation / Q000187:drug effects*; D012130:Respiratory Hypersensitivity / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D006634:Histamine H1 Antagonists; D007546:Isoquinolines; C003722:tritoqualine
vernacular_title: Rhinomanometrische Messung nach intranasaler Allergen-Provokation.