Recombinant DNA technology as it relates to human papillomavirus research.
Recombinant DNA technology has enabled investigators to understand papillomavirus biology. HPV DNA has been found in a variety of benign and malignant tumors. Once discovered, this HPV DNA can be extracted, produced in large quantities, and submitted to nucleotide sequence analysis. Ultimately, this research should reveal the mechanism(s) involved in the malignant transformation of HPV-induced papillomas. It may also help us produce a genetically engineered, safe vaccine against the HPV.
Ostrow
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Department of Microbiology, University of Minnesota Medical School, Minneapolis.
Bender
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D001483:Base Sequence; D015139:Blotting, Southern; D003001:Cloning, Molecular; D004274:DNA, Recombinant; D004279:DNA, Viral / Q000235:genetics; D006801:Humans; D027383:Papillomaviridae / Q000235:genetics*; D012106:Research; D014412:Tumor Virus Infections / Q000235:genetics
D004274:DNA, Recombinant; D004279:DNA, Viral