title: Straight ileoanal anastomosis with preserved anal mucosa for ulcerative colitis and familial polyposis.
abstract: Thirty-two patients were treated with colectomy, mucosal proctectomy, and straight ileoanal anastomosis. Mucosal dissection was performed from the abdominal side, and an anal mucosal brim of 1-2 cm was preserved. Diverting ileostomy was not used, and four patients developed anastomotic leak with pelvic sepsis. Three patients had take-down of the anastomosis for reasons related to the operative method. The remaining patients are all completely continent day and night and have a median stool frequency of 6/24 h 1 year after the operation. The frequency was significantly higher in patients with ulcerative colitis (UC) than in patients with familial polyposis (FP). No dysplasia, ulceration, or stricture formation was found in the preserved mucosa in the UC patients. Regrowth of polyps in the mucosal brim occurred in 10 of 13 FP patients, with atypia in 1. The FP patients had more late complications attributed to extracolonic manifestations of the FP disease.
authors.affiliation: Institute for Surgical Research, National Hospital, Oslo, Norway.
authors.forename: R
authors.initials: R
authors.lastname: Emblem
authors.forename: A
authors.initials: A
authors.lastname: Bergan
authors.forename: S
authors.initials: S
authors.lastname: Larsen
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D001003:Anal Canal / Q000601:surgery*; D000714:Anastomosis, Surgical / Q000009:adverse effects; D002648:Child; D003093:Colitis, Ulcerative / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005753:Gastric Mucosa / Q000473:pathology; D006801:Humans; D007082:Ileum / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011351:Proctoscopy