title: Reservations and recommendations regarding sodium bicarbonate administration in cardiac arrest.
abstract: The American Heart Association's (AHA) revised "Standards and Guidelines for Cardiopulmonary Resuscitation (CPR) and Emergency Cardiac Care (ECC)" recommend that bicarbonate be used ". . . only at the discretion of the physician directing the resuscitation." Reliance upon arterial blood gases is suggested for bicarbonate administration to the patient in cardiac arrest. However, recent literature suggests that arterial blood gases may not reflect the severe cellular acidosis that occurs at the tissue level during cardiac arrest. This article reviews the literature support for this recommendation and for the primary reliance upon hyperventilation to treat the acidosis of cardiac arrest patients. This is a very significant change in the management of the acidosis of cardiac arrest. As with most changes in traditional clinical practice, it will be difficult to overturn years of physician behavior.
authors.affiliation: Department of Emergency Medicine, Highland General Hospital, Oakland, California 94602.
authors.forename: G P
authors.initials: GP
authors.lastname: Young
mesh_terms: D000136:Acid-Base Equilibrium; D000138:Acidosis / Q000188:drug therapy* / Q000209:etiology / Q000378:metabolism; D001639:Bicarbonates / Q000009:adverse effects / Q000627:therapeutic use*; D006323:Heart Arrest / Q000150:complications* / Q000378:metabolism; D006801:Humans; D012964:Sodium / Q000009:adverse effects / Q000627:therapeutic use*; D017693:Sodium Bicarbonate
chemical_list: D001639:Bicarbonates; D017693:Sodium Bicarbonate; D012964:Sodium