[Effect of ketalar on the hypophyseo-adrenal system and glucose-insular homeostasis in children with malignant neoplasms].
The dynamics of content of the adreno-corticotropic and somatotropic hormones, cortisol , insulin and glucose in 30 children with malignant tumors operated upon under conditions of Ketalar anesthesia was analyzed. Direct influence of Ketalar upon the hypophysis-adrenal system and glucose-insular homeostasis was established. A possibility to prevent these changes by means of inclusion of Seduxen in the Ketalar anesthesia scheme was found.
Iagubov
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D000324:Adrenocorticotropic Hormone / Q000097:blood; D000771:Anesthesia, Intravenous; D001786:Blood Glucose / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007328:Insulin / Q000097:blood*; D007649:Ketamine / Q000008:administration & dosage / Q000494:pharmacology*; D009369:Neoplasms / Q000503:physiopathology / Q000601:surgery*; D010913:Pituitary-Adrenal System / Q000187:drug effects* / Q000503:physiopathology; D013268:Stimulation, Chemical
D001786:Blood Glucose; D007328:Insulin; D007649:Ketamine; D000324:Adrenocorticotropic Hormone; D013006:Growth Hormone; D006854:Hydrocortisone
Vliianie ketalara na gipofizarno-nadpochechnikovuiu sistemy i gliukozo-insuliarnyĭ gomeostaz u deteĭ so zlokachestvennymi novoobrazovaniiami.