title: [Heartburn and regurgitation in pregnancy. Efficacy and innocuousness of treatment with Gaviscon suspension].
abstract: This open trial was conducted in 50 pregnant women, presenting during the 2nd and 3rd trimesters of their pregnancy typical symptoms of gastro-esophageal reflux (pyrosis, regurgitations, retro-sternal burning sensations, dyspepsia, epigastric burning). The treatment with Gaviscon, suspension to drink, lasted 1 month at a dose of 2 tablespoons, 4 times/day after meals and in the evening at bedtime. After one month, all symptoms were improved, in a statistically significant fashion, regarding their frequency, intensity and duration. The efficacy is considered positive in 98 p. cent of the cases; the patient's impression is favorable in 70 p. cent of the cases. Tolerance is excellent and the medication is satisfactorily accepted.
authors.affiliation: Maternité Baudelocque, Hôpital Cochin, Paris.
authors.forename: M
authors.initials: M
authors.lastname: Uzan
authors.forename: S
authors.initials: S
authors.lastname: Uzan
authors.forename: C
authors.initials: C
authors.lastname: Sureau
authors.forename: C
authors.initials: C
authors.lastname: Richard-Berthe
mesh_terms: D000328:Adult; D000464:Alginates / Q000627:therapeutic use*; D000536:Aluminum Hydroxide / Q000627:therapeutic use*; D000863:Antacids / Q000627:therapeutic use*; D001639:Bicarbonates / Q000627:therapeutic use*; D004338:Drug Combinations / Q000627:therapeutic use; D004361:Drug Tolerance; D004415:Dyspepsia / Q000188:drug therapy*; D005260:Female; D005764:Gastroesophageal Reflux / Q000188:drug therapy*; D006356:Heartburn / Q000188:drug therapy*; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D012824:Silicic Acid / Q000627:therapeutic use*; D012822:Silicon Dioxide / Q000627:therapeutic use*; D017693:Sodium Bicarbonate
chemical_list: D000464:Alginates; D000863:Antacids; D001639:Bicarbonates; D004338:Drug Combinations; D012824:Silicic Acid; D000536:Aluminum Hydroxide; C007829:alginate, aluminium hydroxide, magnesium trisilicate, sodium bicarbonate drug combination; D012822:Silicon Dioxide; D017693:Sodium Bicarbonate
vernacular_title: Pyrosis et régurgitations au cours de la grossesse. Efficacité et innocuité d'un traitement par Gaviscon suspension.