Preliminary evidence for the utility of carbamazepine in alprazolam withdrawal.
Alprazolam treatment is effective for panic disorder, but its major disadvantages include possible dependence and withdrawal symptoms upon discontinuation. The authors report three cases in which carbamazepine, a clinically effective anticonvulsant without abuse potential, successfully attenuated alprazolam withdrawal symptoms.
Klein
E
E
Uhde
T W
TW
Post
R M
RM
D000328:Adult; D000525:Alprazolam; D014151:Anti-Anxiety Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001008:Anxiety Disorders / Q000188:drug therapy; D001569:Benzodiazepines / Q000009:adverse effects* / Q000627:therapeutic use; D002220:Carbamazepine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D010200:Panic; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy* / Q000209:etiology
D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D002220:Carbamazepine; D000525:Alprazolam