Rat yolk-sac antigen-2 defined by monoclonal antibodies.
The distribution of the rat yolk-sac antigen-2 (Rat YSA-2) as defined by a monoclonal antibody raised against rat yolk-sac carcinoma cells is described. The antigen is present on rat yolk-sac carcinoma, on parietal yolk-sac endoderm and on the epithelium of fetal and adult gut and of the adult proximal kidney tubules. It is not present on a variety of rat tumors other than yolk-sac carcinomas and not detectable on pre-implantation and post-implantation embryos. Rat YSA-2 differs from YSA-I, other stage-specific embryonic antigens, basement membrane antigens, intestinal and tubular antigens.
Van Hove
L
L
Sobis
H
H
Lu
Y L
YL
Vandeputte
M
M
D000818:Animals; D000911:Antibodies, Monoclonal; D002460:Cell Line; D006224:Cricetinae; D005260:Female; D005434:Flow Cytometry; D006017:Glycolipids / Q000276:immunology*; D006801:Humans; D007163:Immunosorbent Techniques; D007797:Laminin / Q000276:immunology; D016256:Lewis X Antigen; D008649:Mesonephroma / Q000032:analysis*; D051379:Mice; D010051:Ovarian Neoplasms / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains; D014018:Tissue Distribution
D000911:Antibodies, Monoclonal; D006017:Glycolipids; D007797:Laminin; D016256:Lewis X Antigen