Characterisation of two different types of poliovirus isolated from a patient.
A clinical case of paralytic poliomyelitis with almost simultaneous isolation of two different types of poliovirus was investigated. A strain of poliovirus type I was isolated from the cerebrospinal fluid and a type 3 strain of poliovirus was isolated from the patient's faeces. Both strains were characterised by two-dimensional oligonucleotide mapping. The type I virus was shown to be of wild type while the type 3 virus was shown to be vaccine-associated.
Tsilimigras
C W
CW
National Institute for Virology, University of the Witwatersrand Medical School, Johannesburg, Republic of South Africa.
Schoub
B D
BD
D000818:Animals; D002555:Cerebrospinal Fluid / Q000382:microbiology; D002675:Child, Preschool; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D009710:Nucleotide Mapping; D011051:Poliomyelitis / Q000382:microbiology*; D017955:Poliovirus / Q000145:classification / Q000302:isolation & purification*; D011055:Poliovirus Vaccine, Oral; D012367:RNA, Viral / Q000032:analysis; D013019:South Africa
D011055:Poliovirus Vaccine, Oral; D012367:RNA, Viral