title: Central motor and sensory conduction in adrenoleukomyeloneuropathy, cerebrotendinous xanthomatosis, HTLV-1-associated myelopathy and tabes dorsalis.
abstract: Central motor and sensory conduction was studied by percutaneous electrical stimulation of brain and spinal cord and by somatosensory evoked potential techniques respectively, in patients with adrenoleukomyeloneuropathy, cerebrotendinous xanthomatosis, human T-cell lymphotropic virus-1-associated myelopathy and tabes dorsalis. The results were all consistent with clinical and neuropathological findings in these disorders. Conductions in the corticospinal tract and posterior column could be evaluated separately with these two techniques. Percutaneous electrical stimulation technique would be useful for investigating conduction in the corticospinal tract in patients with spinal cord disorders.
authors.affiliation: Department of Neurology, School of Medicine, University of Tokyo, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Ugawa
authors.forename: N
authors.initials: N
authors.lastname: Kohara
authors.forename: T
authors.initials: T
authors.lastname: Shimpo
authors.forename: T
authors.initials: T
authors.lastname: Mannen
mesh_terms: D000326:Adrenoleukodystrophy / Q000503:physiopathology*; D000328:Adult; D000344:Afferent Pathways / Q000503:physiopathology; D000368:Aged; D001921:Brain / Q000503:physiopathology; D001927:Brain Diseases / Q000503:physiopathology*; D002524:Cerebellar Ataxia / Q000503:physiopathology; D002549:Diffuse Cerebral Sclerosis of Schilder / Q000503:physiopathology*; D005073:Evoked Potentials, Somatosensory; D005260:Female; D015490:HTLV-I Infections / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology*; D010525:Peripheral Nerves / Q000503:physiopathology; D011712:Pyramidal Tracts / Q000503:physiopathology; D013116:Spinal Cord / Q000503:physiopathology; D013118:Spinal Cord Diseases / Q000503:physiopathology*; D009435:Synaptic Transmission; D013606:Tabes Dorsalis / Q000503:physiopathology*; D014973:Xanthomatosis / Q000503:physiopathology*