title: Evidence for HTLV-I associated with mycosis fungoides and B-cell chronic lymphocytic leukemia.
abstract: Human T-cell lymphotropic virus type I (HTLV-I) is a human retrovirus that can transform T-helper lymphocytes and is etiologically associated with adult T-cell lymphoma/leukemia. Mycosis fungoides represents a primary cutaneous lymphoma of helper T-cell origin, while chronic lymphocytic leukemia is generally considered to be a neoplastic B-lymphocyte disorder. Our patient had HTLV-I with coexistent mycosis fungoides and B-cell chronic lymphocytic leukemia. The concurrent lymphoid proliferations may represent HTLV-I-associated abnormalities of immunoregulation.
authors.forename: A
authors.initials: A
authors.lastname: Peterman
authors.forename: M
authors.initials: M
authors.lastname: Jerdan
authors.forename: S
authors.initials: S
authors.lastname: Staal
authors.forename: B
authors.initials: B
authors.lastname: Bender
authors.forename: H
authors.initials: H
authors.lastname: Striecher
authors.forename: J
authors.initials: J
authors.lastname: Schüpbach
authors.forename: L
authors.initials: L
authors.lastname: Resnick
mesh_terms: D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis*; D001402:B-Lymphocytes; D017977:Deltaretrovirus / Q000276:immunology*; D015480:Deltaretrovirus Antibodies; D006801:Humans; D007945:Leukemia, Lymphoid / Q000150:complications / Q000382:microbiology*; D008297:Male; D009182:Mycosis Fungoides / Q000150:complications / Q000276:immunology / Q000382:microbiology* / Q000473:pathology; D012867:Skin / Q000276:immunology / Q000382:microbiology / Q000473:pathology
chemical_list: D000914:Antibodies, Viral; D015480:Deltaretrovirus Antibodies