Intraoperative blood pressure control by ATP in pheochromocytoma.
Three cases of pheochromocytoma which were successfully treated with the use of adenosine triphosphate (ATP) during the operation are reported. The mechanism of the hypotensive effect of ATP has been proved due to the antagonizing action of the agent to the vasoconstriction by noradrenaline and/or sympathetic nerve stimulation. In these 3 cases, ATP has been safely and effectively applied to control blood pressure in pheochromocytoma. ATP could be used as the first-choice drug to keep the circulatory state stable during surgery for pheochromocytoma.
Aso
Y
Y
Tajima
A
A
Suzuki
K
K
Ohmi
Y
Y
Kanbayashi
T
T
Mitsuhashi
T
T
Ikeda
K
K
D000255:Adenosine Triphosphate / Q000627:therapeutic use*; D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000601:surgery*; D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D001794:Blood Pressure / Q000187:drug effects*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000209:etiology; D007430:Intraoperative Care; D008875:Middle Aged; D010673:Pheochromocytoma / Q000150:complications / Q000601:surgery*
D000317:Adrenergic alpha-Antagonists; D000319:Adrenergic beta-Antagonists; D000255:Adenosine Triphosphate