title: [Determination of heterophilic antibodies in infants: apropos of nine cases].
abstract: The most frequent and known disease produced by Epstein-Barr virus is infectious mononucleosis. It is usually diagnosed after the age of two in pediatric practice based on the characteristic hematologic picture and Paul-Bunnell test. In infants there is rarely communications of this cases in the literature and, moreover, Paul-Bunnell test is commonly negative. We have collected nine infants below two years old with mononucleosis syndrome characteristic hematologic picture and with heterophil antibodies positive reaction in all of them. Clinical and laboratory finding, and it likely relation to the EBV infection are discussed.
authors.affiliation: Unidad de Lactantes, Hospital 1. de Octubre, Madrid.
authors.forename: S
authors.initials: S
authors.lastname: Negreira Cepeda
authors.forename: E
authors.initials: E
authors.lastname: Medina Benítez
authors.forename: F
authors.initials: F
authors.lastname: García-Muñoz Rodrigo
mesh_terms: D000910:Antibodies, Heterophile / Q000276:immunology*; D004854:Herpesvirus 4, Human / Q000276:immunology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007244:Infectious Mononucleosis / Q000276:immunology*
chemical_list: D000910:Antibodies, Heterophile
vernacular_title: Determinación de anticuerpos heterófilos en lactantes: a propósito de nueve casos.