Bucolome N-glucuronide: purification and identification of a major metabolite of bucolome in rat bile.
A biliary metabolite of bucolome in rat was isolated and purified by column chromatography. The metabolite has been identified as bucolome N3-glucuronide by chemical and spectroscopic data. This study is the first to show an N-glucuronide to be the major metabolite of barbiturates in rat bile.
Mohri
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K
Uesugi
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Kamisaka
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D000818:Animals; D001463:Barbiturates / Q000031:analogs & derivatives / Q000302:isolation & purification / Q000378:metabolism*; D001646:Bile / Q000378:metabolism; D001711:Biotransformation; D055598:Chemical Phenomena; D002621:Chemistry; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D001463:Barbiturates; C046662:bucolome N-glucuronide