title: [Deletional and insertional analysis of the antitumorigenicity of the plasmid R388 in Agrobacterium tumefaciens].
abstract: The study of the plasmid R388 deletional derivatives has shown the antitumorigenicity determinant of the plasmid to be contained by the tra-operon. Transposon Tn5 has been used for selection of a number of insertional mutants having lost the antitumorigenic properties. The difference in the locations of Tn5 inserts was found, all of the latter being localized within the tra-operon. The data obtained suggest the locus of the plasmid R388 responsible for its antitumorigenic properties to be located in the region of tra-genes distally to the rep-region.
authors.forename: G V
authors.initials: GV
authors.lastname: Mashkovskaia
authors.forename: T S
authors.initials: TS
authors.lastname: Denisova
authors.forename: E V
authors.initials: EV
authors.lastname: Lovanok
authors.forename: V V
authors.initials: VV
authors.lastname: Fomicheva
authors.forename: N A
authors.initials: NA
authors.lastname: Kartel'
mesh_terms: D015197:Carcinogenicity Tests; D002872:Chromosome Deletion; D004251:DNA Transposable Elements; D009154:Mutation; D009876:Operon; D010957:Plasmids; D015183:Restriction Mapping; D012231:Rhizobium / Q000235:genetics*
chemical_list: D004251:DNA Transposable Elements
vernacular_title: Deletsionnyĭ i insertsionnyĭ analiz antionkogennosti plazmidy R388 uAgrobacterium tumefaciens.