No evidence for linkage between the loci for coagulation factor XIII-A and HLA.
The linkage analysis between the locus for coagulation factor XIII-A (F13A) and HLA region genes (HLA-A, -C, -B) was performed. In males, the maximum of lod scores between F13A and HLA was 0.33 at 0 = 0.30, and in females lod scores were negative at all values of 0. The results provided no evidence for close linkage between F13A and HLA genes.
Nishigaki
T
T
Tokunaga
K
K
Ishii
C
C
Omoto
K
K
Akaza
T
T
Akiyama
N
N
Juji
T
T
Murata
S
S
Naito
S
S
Saji
H
H
D002874:Chromosome Mapping; D005176:Factor XIII / Q000235:genetics*; D005260:Female; D008040:Genetic Linkage; D005819:Genetic Markers; D006680:HLA Antigens / Q000235:genetics*; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D015236:HLA-C Antigens; D006801:Humans; D008126:Lod Score; D008297:Male; D011503:Transglutaminases
D005819:Genetic Markers; D006680:HLA Antigens; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D015236:HLA-C Antigens; D005176:Factor XIII; D011503:Transglutaminases