title: Genome of the European elk papillomavirus (EEPV).
abstract: The genome of the European elk papillomavirus (EEPV) was found to be 8,095 base pairs (bp) long and its genetic organization was similar to that of other papillomaviruses. Ten open reading frames (ORFs), designated E1-E7 and L1-L3, were identified in the genome, all located on one strand. The presence of the L3 ORF is rare among the papillomaviruses and to date has only been identified in the genomes of EEPV, the deer papillomavirus (DPV) and the Cottontail papillomavirus (CRPV). The ORF is well conserved between DPV and EEPV with regard to both length and sequence. Potential promoter regions were identified at the 5'-end of the E6 ORF, at the 3'-end of the E1 ORF and downstream of the L1 ORF. Furthermore, two potential polyadenylation signals were found, one located in the long control region (LCR), downstream of the L1 ORF, and another preceding the L2 ORF. The EEVP genome is closely related to the genome of the DPV, the most highly conserved regions being ORFs E1 (70%), E5 (69%), and L1 (74%).
authors.affiliation: Department of Veterinary Microbiology (Virology), Swedish University of Agriculture Sciences, Uppsala.
authors.forename: A
authors.initials: A
authors.lastname: Eriksson
authors.forename: H
authors.initials: H
authors.lastname: Ahola
authors.forename: U
authors.initials: U
authors.lastname: Pettersson
authors.forename: J
authors.initials: J
authors.lastname: Moreno-Lopez
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004270:DNA, Circular; D004279:DNA, Viral; D005814:Genes, Viral; D008969:Molecular Sequence Data; D027383:Papillomaviridae / Q000235:genetics*; D011401:Promoter Regions, Genetic; D012689:Sequence Homology, Nucleic Acid
chemical_list: D004270:DNA, Circular; D004279:DNA, Viral