Serological evidence of Hantaan virus infection in the United States.
We found low titers of fluorescent antibodies against Hantaan virus, the etiologic agent of Korean hemorrhagic fever, in sera from 7 of 1,035 patients with febrile illnesses of unknown origin and from 6 of 664 blood donors in the United States. All but 1 of these individuals possessed neutralizing antibodies against Hantaan virus. This was a 31-year-old research technician who had worked with laboratory rodents with virus-induced tumors, but had not traveled abroad, suggesting that infection with Hantaan virus or a closely related agent was locally acquired. However, the precise source of his infection remains unclear.
Yanagihara
R
R
Chin
C T
CT
Weiss
M B
MB
Gajdusek
D C
DC
Diwan
A R
AR
Poland
J B
JB
Kleeman
K T
KT
Wilfert
C M
CM
Meiklejohn
G
G
Glezen
W P
WP
D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D005260:Female; D005455:Fluorescent Antibody Technique; D006476:Orthohantavirus / Q000276:immunology*; D006480:Hemorrhagic Fever with Renal Syndrome / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009500:Neutralization Tests; D012328:RNA Viruses / Q000276:immunology*; D014481:United States
D000914:Antibodies, Viral