title: Autoimmune thyroid disease.
abstract: The concept of thyroid autoimmune disease now includes the following clinical entities: 1 degree thyrotoxicosis and goitrous thyroiditis (Hashimoto) with their variants, and 1 degree myxedema (atrophic thyroiditis); some cases of sporadic nontoxic goiters; most cases of neonatal hyperthyroidism; and a proportion of congenital athyreotic cretinism. Endocrine exophthalmos, though clinically associated with Graves' disease, is now considered a separate immunological entity.
authors.forename: G F
authors.initials: GF
authors.lastname: Bottazzo
authors.forename: D
authors.initials: D
authors.lastname: Doniach
mesh_terms: D000818:Animals; D000917:Antibody Formation; D001323:Autoantibodies / Q000032:analysis; D001327:Autoimmune Diseases; D002478:Cells, Cultured; D003409:Congenital Hypothyroidism / Q000151:congenital / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D006042:Goiter / Q000276:immunology; D006044:Goiter, Nodular / Q000276:immunology; D006111:Graves Disease / Q000175:diagnosis / Q000276:immunology; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II / Q000032:analysis; D006801:Humans; D006980:Hyperthyroidism / Q000175:diagnosis / Q000276:immunology; D007037:Hypothyroidism / Q000276:immunology; D007074:Immunoglobulin G / Q000032:analysis; D018828:Immunoglobulins, Thyroid-Stimulating; D007231:Infant, Newborn; D009230:Myxedema / Q000276:immunology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology; D011644:Puerperal Disorders / Q000276:immunology; D051381:Rats; D013959:Thyroid Diseases / Q000175:diagnosis / Q000276:immunology*; D013961:Thyroid Gland / Q000166:cytology / Q000276:immunology; D013967:Thyroiditis, Autoimmune / Q000276:immunology; D013972:Thyrotropin / Q000276:immunology
chemical_list: D001323:Autoantibodies; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II; D007074:Immunoglobulin G; D018828:Immunoglobulins, Thyroid-Stimulating; D013972:Thyrotropin