title: Low plasma cyclic nucleotides in multiple sclerosis.
abstract: The concentrations of cyclic AMP and cyclic GMP were estimated in plasma of 26 patients with definite multiple sclerosis (MS) in relapse, and compared to that of 26 sex- and age-matched healthy controls. MS patients had significantly lower levels of both nucleotides. The levels of c-GMP correlated negatively to the Disability Status Scale score.
authors.affiliation: Athens University Medical School, Eginition Hospital, Greece.
authors.forename: M
authors.initials: M
authors.lastname: Markianos
authors.forename: C
authors.initials: C
authors.lastname: Sfagos
mesh_terms: D000328:Adult; D000242:Cyclic AMP / Q000097:blood*; D006152:Cyclic GMP / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000097:blood* / Q000503:physiopathology
chemical_list: D000242:Cyclic AMP; D006152:Cyclic GMP