Effect of vecuronium on intraocular pressure.
Intraocular pressure decreased by 22.6% in association with neuromuscular blockade produced by vecuronium 0.1 mg kg-1. This appeared to be the result of an indirect action possibly via an effect on CVP. Vecuronium would be a suitable neuromuscular blocker for patients undergoing eye surgery in whom an increase in IOP would be undesirable.
Jantzen
J P
JP
Hackett
G H
GH
Erdmann
K
K
Earnshaw
G
G
D000328:Adult; D000368:Aged; D000768:Anesthesia, General; D002496:Central Venous Pressure / Q000187:drug effects; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D009466:Neuromuscular Blocking Agents / Q000494:pharmacology*; D010197:Pancuronium / Q000031:analogs & derivatives* / Q000494:pharmacology; D014673:Vecuronium Bromide
D009466:Neuromuscular Blocking Agents; D014673:Vecuronium Bromide; D010197:Pancuronium