[Effect of somatostatin on the neurosecretory cells of the hypothalamic paraventricular nucleus and argentaffin cells of the antral part of the rat stomach].
Administration of somatostatin induced changes of functional activity in all the central and peripheral structures under study. Neuronal activity in the paraventricular nucleus decreased by the 3rd and 15th min after somatostatin injection whereas by the 20th min the firing rate increased. Amount of argenaffin cells was sharply reduced, at that, between the 4th and 15th min which suggested an active release of enterochromaffin cell granules into the blood.
Kotel'nikova
V I
VI
Chernysheva
M P
MP
Lutsik
E A
EA
Mileĭkovskii
B Iu
BIu
Ardemasova
Z A
ZA
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D002452:Cell Count; D002838:Chromaffin System / Q000187:drug effects*; D004759:Enterochromaffin Cells / Q000187:drug effects* / Q000502:physiology; D008297:Male; D009474:Neurons / Q000187:drug effects / Q000502:physiology; D009490:Neurosecretory Systems / Q000187:drug effects*; D010286:Paraventricular Hypothalamic Nucleus / Q000187:drug effects* / Q000502:physiology; D011706:Pyloric Antrum / Q000187:drug effects*; D051381:Rats; D011930:Reaction Time / Q000187:drug effects; D013004:Somatostatin / Q000494:pharmacology*
D013004:Somatostatin
Vliianie somatostatina na neĭrosekretornye kletki paraventrikuliarnogo iadra gipotalamusa i argentaffinnye kletki antral'nogo otdela zheludka krysy.