Pressor effects of alcohol in normotensive and hypertensive subjects.
The effects of acute alcohol consumption and abstinence on blood pressure were studied in normal healthy subjects and in non-drinking and regularly drinking hypertensive patients. All subjects drank alcohol (1 g/kg body weight daily) for 5 days then abstained for 5 days. There was no significant difference in blood pressure in normal subjects during and after alcohol ingestion. However, in hypertensive non-drinkers both systolic and diastolic pressures when standing were significantly higher during the period of alcohol intake; supine blood pressure was not significantly higher. In hypertensive patients who drank regularly, standing and supine systolic and diastolic blood pressures were significantly higher during the period of drinking.
Malhotra
H
H
Mehta
S R
SR
Mathur
D
D
Khandelwal
P D
PD
D000328:Adult; D000428:Alcohol Drinking; D001794:Blood Pressure / Q000187:drug effects*; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011187:Posture
D000431:Ethanol