title: Selenium deficiency and possible increased risk of carcinoma in adults with cystic fibrosis.
abstract: 20 young adults with cystic fibrosis (CF), including 2 with cancer, were found to have low serum selenium concentrations. Serum vitamin E concentrations were also low. It is suggested that low levels of circulating selenium are associated with increased risk of carcinoma, particularly in the presence of reduced vitamin E levels. Older patients with CF may be at increased risk for the development of carcinoma.
authors.forename: R J
authors.initials: RJ
authors.lastname: Stead
authors.forename: A N
authors.initials: AN
authors.lastname: Redington
authors.forename: L J
authors.initials: LJ
authors.lastname: Hinks
authors.forename: B E
authors.initials: BE
authors.lastname: Clayton
authors.forename: M E
authors.initials: ME
authors.lastname: Hodson
authors.forename: J C
authors.initials: JC
authors.lastname: Batten
mesh_terms: D000328:Adult; D003550:Cystic Fibrosis / Q000097:blood* / Q000150:complications; D005260:Female; D006801:Humans; D007078:Ileal Neoplasms / Q000209:etiology*; D008297:Male; D010190:Pancreatic Neoplasms / Q000209:etiology*; D012306:Risk; D012643:Selenium / Q000097:blood / Q000172:deficiency*; D014810:Vitamin E / Q000097:blood
chemical_list: D014810:Vitamin E; D012643:Selenium