title: Haemorrhagic necrotising enteritis in foals associated with Clostridium perfringens.
abstract: Two foals aged 35 and 48 h from 2 Thoroughbred studs died several hours after developing clinical signs of depression, severe haemorrhagic diarrhoea and dehydration. Both foals had an acute haemorrhagic enteritis extending from the anterior jejunum to the terminal ileum which was characterised histologically by villus necrosis. Necrotic villi were surrounded by large numbers of rod-shaped Gram positive bacteria. Clostridium perfringens was recovered from the intestines of both foals and the isolates were considered to be C. perfringens type C. Other cases of diarrhoea were also observed in foals of the same age on these 2 studs, but the aetiology of these was not determined.
authors.forename: L D
authors.initials: LD
authors.lastname: Sims
authors.forename: S
authors.initials: S
authors.lastname: Tzipori
authors.forename: G H
authors.initials: GH
authors.lastname: Hazard
authors.forename: C L
authors.initials: CL
authors.lastname: Carroll
mesh_terms: D000818:Animals; D003016:Clostridium perfringens / Q000302:isolation & purification; D003967:Diarrhea / Q000662:veterinary; D004761:Enterocolitis, Pseudomembranous / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D006734:Horse Diseases / Q000209:etiology* / Q000473:pathology; D006736:Horses; D007421:Intestine, Small / Q000473:pathology