title: Transfer of passive immunity from mother to young in a teleost fish: haemagglutinating activity in the serum and eggs of plaice, Pleuronectes platessa L.
abstract: Plaice were immunized against rabbit red blood cells (rbc) and the haemagglutinating activity in their sera and eggs was isolated by gel filtration in Sephacryl S300 SF. A "heavy" (greater than 6.69 X 10(5) Daltons) and a "light" (less than 2.32 X 10(5) Daltons) component of haemagglutinating activity were present in plaice immune serum and eggs. The "heavy" haemagglutinating component had the characteristics of immunoglobulin M (IgM) antibody. By contrast the "light" component was suppressed greatly by monosaccharides but not by 2-mercaptoethanol (2-ME) and it was not precipitable against heterologous rabbit anti-plaice Ig immune serum. Since this "light" component was also identified in the serum and eggs of non-immunized plaice the activity was attributed to non-specific lectin-like activity. The presence of an inducible, high molecular weight, haemagglutinating Ig-like protein in plaice serum and eggs suggests the possibility of transfer of passive adaptive immunity from mother to young in this fish.
authors.forename: J E
authors.initials: JE
authors.lastname: Bly
authors.forename: A S
authors.initials: AS
authors.lastname: Grimm
authors.forename: I G
authors.initials: IG
authors.lastname: Morris
mesh_terms: D000818:Animals; D002850:Chromatography, Gel; D004912:Erythrocytes / Q000276:immunology; D005399:Fishes / Q000276:immunology*; D006384:Hemagglutination; D006386:Hemagglutination Tests; D006388:Hemagglutinins / Q000302:isolation & purification*; D007112:Immunity, Maternally-Acquired; D007122:Immunoelectrophoresis; D007075:Immunoglobulin M; D007136:Immunoglobulins / Q000032:analysis; D010063:Ovum / Q000276:immunology*; D011817:Rabbits
chemical_list: D006388:Hemagglutinins; D007075:Immunoglobulin M; D007136:Immunoglobulins