title: Prospective evaluation of risk of cervical cancer after cytological evidence of human papilloma virus infection.
abstract: 846 women with cytological evidence of human papillomavirus infection on their Papanicolaou smears in 1979 were followed for the subsequent development of cervical malignant disorders. Carcinoma-in-situ developed in 30 women during the next 6 years, compared with an expected number of 1.9 by general population incidence figures, giving a relative risk of 15.6. The risk was greatly increased (38.7) in women younger than 25 years when the cytological diagnosis of human papillomavirus infection was made.
authors.forename: H
authors.initials: H
authors.lastname: Mitchell
authors.forename: M
authors.initials: M
authors.lastname: Drake
authors.forename: G
authors.initials: G
authors.lastname: Medley
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001315:Australia; D001706:Biopsy; D002278:Carcinoma in Situ / Q000453:epidemiology / Q000473:pathology; D003581:Cytodiagnosis; D005260:Female; D006801:Humans; D008403:Mass Screening; D008875:Middle Aged; D065006:Papanicolaou Test; D027383:Papillomaviridae; D011446:Prospective Studies; D012306:Risk; D014412:Tumor Virus Infections / Q000150:complications* / Q000175:diagnosis; D002577:Uterine Cervical Diseases / Q000150:complications*; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D014626:Vaginal Smears