Chronic benzodiazepine treatment increases the effects of inverse agonists.
D000818:Animals; D014151:Anti-Anxiety Agents / Q000008:administration & dosage / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D003292:Convulsants; D004357:Drug Synergism; D004361:Drug Tolerance; D005479:Flurazepam / Q000494:pharmacology; D008124:Locomotion / Q000187:drug effects; D051379:Mice; D008815:Mice, Inbred Strains; D011963:Receptors, GABA-A / Q000187:drug effects*
D014151:Anti-Anxiety Agents; D003292:Convulsants; D011963:Receptors, GABA-A; D005479:Flurazepam