Antibiotic dependence in a strain of Neisseria pharyngis.
A strain of Neisseria pharyngis was isolated in pure culture from a specimen of sputum. Growth was markedly enhanced by sub-lethal concentrations of rifampicin, spectinomycin, erythromycin and clindamycin. The effect was temporary with tetracycline. The possible mechanisms of this phenomenon are discussed.
D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002981:Clindamycin / Q000494:pharmacology; D004917:Erythromycin / Q000494:pharmacology; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D009343:Neisseria / Q000187:drug effects* / Q000254:growth & development; D012293:Rifampin / Q000494:pharmacology; D000198:Spectinomycin / Q000494:pharmacology; D013183:Sputum / Q000382:microbiology; D013752:Tetracycline / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D002981:Clindamycin; D004917:Erythromycin; D000198:Spectinomycin; D013752:Tetracycline; D012293:Rifampin