Comparative acute toxicity of DDT metabolites among American and European species of planarians.
1. DDT metabolism in a North American species of planarian leads to the formation of metabolites more toxic than the parent compound. 2. The increased toxicity of DDT metabolites is similar to acute toxicity data reported previously in a European species. 3. It is suggested that planarians lack a direct mechanism for DDT detoxification, since two North American and one European species are known to metabolize DDT initially to DDE and DDD.
D000818:Animals; D001711:Biotransformation; D003634:DDT / Q000633:toxicity*; D003633:Dichlorodiphenyl Dichloroethylene / Q000633:toxicity; D003632:Dichlorodiphenyldichloroethane / Q000633:toxicity; D010932:Planarians / Q000378:metabolism*; D013045:Species Specificity; D014419:Turbellaria / Q000378:metabolism*
D003633:Dichlorodiphenyl Dichloroethylene; D003634:DDT; D003632:Dichlorodiphenyldichloroethane