Comparison of visual and measured train-of-four recovery after vecuronium-induced neuromuscular blockade using two anaesthetic techniques.
This study evaluated train-of-four recovery after the administration of vecuronium, comparing measured with visually observed responses. Responses to supramaximal stimuli of the ulnar nerves were measured by a force transducer, and compared with visually observed movements of the contralateral thumb. For the 10 patients anaesthetized with nitrous oxide and enflurane, the second, third and fourth twitches visually reappeared at 84 (+/- 10)%, 76 (+/- 11)%, and 70 (+/- 12)% measured blockade, respectively. For the other 10 patients, anaesthetized with a narcotic-barbiturate technique, the second, third and fourth twitches reappeared at 81 (+/- 8)%, 68 (+/- 9)%, and 59 (+/- 11)%. These results were not different for the two anaesthetic techniques.
D000768:Anesthesia, General / Q000379:methods*; D000769:Anesthesia, Inhalation; D004737:Enflurane; D005260:Female; D006801:Humans; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects*; D009466:Neuromuscular Blocking Agents; D009609:Nitrous Oxide; D013874:Thiopental; D014159:Transducers; D014673:Vecuronium Bromide / Q000494:pharmacology*; D014796:Visual Perception
D009466:Neuromuscular Blocking Agents; D014673:Vecuronium Bromide; D004737:Enflurane; D013874:Thiopental; D009609:Nitrous Oxide