title: Effects of adrenaline on the isolated heart of the trout (Salmo gairdneri R.) before and after transfer from fresh water to sea water.
abstract: 1. Adrenaline induces positive inotropic and chronotropic effects on the isolated heart of the trout (Salmo gairdnerii) via the stimulation of beta adrenoreceptors. 2. The effects are relatively more marked in winter than in spring. But there is no seasonal variation as in the cel. The intrinsic reactivity of the heart is not basically modified after a transfer from fresh water to sea water. 3. However, after such a transfer, adrenaline induces an increase of the membrane resting potential which suggests that adrenaline can enhance the activity of the Na/K pump and/or modify the Ca/K balance and could improve the cardiac performances during the "crisis period" following the transfer.
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D004524:Eels; D004837:Epinephrine / Q000494:pharmacology*; D005618:Fresh Water; D006321:Heart / Q000187:drug effects*; D006339:Heart Rate / Q000187:drug effects; D009200:Myocardial Contraction / Q000187:drug effects; D009206:Myocardium / Q000201:enzymology; D012487:Salmonidae / Q000378:metabolism*; D012621:Seasons; D012623:Seawater; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism; D014337:Trout / Q000378:metabolism*; D014867:Water
chemical_list: D014867:Water; D000251:Adenosine Triphosphatases; C029321:calcium potassium ATPase; D000254:Sodium-Potassium-Exchanging ATPase; D004837:Epinephrine