Assessing the efficacy of antianxiety agents.
Proper evaluation of anxiolytic therapy, involving the possible use of rating scales as well as the physician's skill in observation and communication, is essential in identifying the most appropriate treatment for a given patient and facilitating the management of therapy. These issues are discussed herein, using the clinical trials of buspirone, a new, nonsedating antianxiety agent, as a model for the process of drug selection.
D014151:Anti-Anxiety Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001008:Anxiety Disorders / Q000188:drug therapy* / Q000523:psychology; D002065:Buspirone; D002986:Clinical Trials as Topic; D003975:Diazepam / Q000008:administration & dosage / Q000627:therapeutic use; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D006801:Humans; D010555:Personality Inventory; D011569:Psychiatric Status Rating Scales; D011743:Pyrimidines / Q000008:administration & dosage / Q000627:therapeutic use; D011897:Random Allocation
D014151:Anti-Anxiety Agents; D011743:Pyrimidines; D003975:Diazepam; D002065:Buspirone