Junín virus persistence in mice.
Newborn mice surviving intracerebral infection with Junín virus (JV) strain XJ showed viral persistence in brain up to 140 days post-infection (p.i.). Mild meningoencephalitis or encephalitis, but not the neutralizing antibody titres (NtAb) correlated with virus presence.
D000818:Animals; D000831:Animals, Newborn; D000914:Antibodies, Viral / Q000032:analysis; D001116:Arenaviridae / Q000302:isolation & purification*; D006477:Arenaviruses, New World / Q000276:immunology / Q000302:isolation & purification*; D001921:Brain / Q000382:microbiology*; D004660:Encephalitis / Q000382:microbiology; D006478:Hemorrhagic Fever, American / Q000382:microbiology*; D007668:Kidney / Q000382:microbiology; D008590:Meningoencephalitis / Q000382:microbiology; D051379:Mice; D009500:Neutralization Tests; D013154:Spleen / Q000382:microbiology; D013997:Time Factors; D014709:Vero Cells
D000914:Antibodies, Viral