title: Differences in adhesiveness among type 1 fimbriate strains of Enterobacteriaceae revealed by an in vitro HEp2 cell adhesion model.
abstract: Ten type 1 fimbriate strains of Enterobacteriaceae were examined in an in vitro adhesion assay with HEp2 epithelial cells. The range of HEp2 cell adhesiveness, which was characteristic for each strain, was affected by motility, type 1 fimbriation and production of mannose sensitive haemagglutinin. Nevertheless, not all type 1 fimbriate strains adhered well in this model. The findings are discussed with regard to the possibility that different type 1 fimbriate enterobacteria, though all are mannose sensitive, recognize different mannose-containing receptors present or available on the surfaces of the HEp2 cells.
mesh_terms: D001422:Bacterial Adhesion; D002460:Cell Line; D004754:Enterobacter / Q000502:physiology / Q000648:ultrastructure; D004755:Enterobacteriaceae / Q000502:physiology* / Q000648:ultrastructure; D004926:Escherichia coli / Q000502:physiology / Q000648:ultrastructure; D010861:Fimbriae, Bacterial / Q000145:classification / Q000502:physiology*; D007711:Klebsiella pneumoniae / Q000502:physiology / Q000648:ultrastructure; D008954:Models, Biological; D012486:Salmonella typhimurium / Q000502:physiology / Q000648:ultrastructure; D012763:Shigella flexneri / Q000502:physiology / Q000648:ultrastructure