[Serum amine oxidases and gamma-glutamyl transpeptidase activity in burns].
Activities of amine oxidases (benzylamine, 4-nitrobenzylamine, 4-dimethylamine methylbenzylamine used as substrates) and of gamma-glutamyl transpeptidase were studied in blood serum of 72 patients with thermic burns of various intensity and degree. Severity of the disease correlated with the rate of amine oxidases activity alteration. Distinct and long-term decrease in oxidation of benzylamine as well as simultaneous stimulation of 4-dimethylamine methylbenzylamine oxidation were observed in severe forms of the burns disease, thus suggesting the increase in diamine oxidase activity. This phenomenon proved to be an unfavourable prognostic indication of the disease. Alterations in activity of gamma-glutamyl transpeptidase corresponded to severity of the burns disease. Estimation of the enzymatic activity might be used in evaluation of the impairments severity as well as in prognosis of burns disease development.
D000328:Adult; D002056:Burns / Q000201:enzymology* / Q000628:therapy; D005260:Female; D006464:Hemoperfusion; D006801:Humans; D008297:Male; D008875:Middle Aged; D000587:Oxidoreductases Acting on CH-NH Group Donors / Q000097:blood*; D011379:Prognosis; D005723:gamma-Glutamyltransferase / Q000097:blood*
D000587:Oxidoreductases Acting on CH-NH Group Donors; D005723:gamma-Glutamyltransferase
Aktivnost' syvorotochnykh aminoksidaz i gamma-glutamiltrans- peptidazy pri ozhogovoĭ bolezni.