title: Congenital absence of insulin-secreting cells.
abstract: A male infant was diagnosed as having diabetes mellitus 1 d after birth and died on the third day. Histological examination of the pancreas showed small and inconspicuous islets of Langerhans that were completely devoid of insulin-secreting cells. There was no evidence of insulitis.
mesh_terms: D003920:Diabetes Mellitus / Q000151:congenital* / Q000473:pathology; D005934:Glucagon / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D007231:Infant, Newborn; D007328:Insulin / Q000032:analysis; D007515:Islets of Langerhans / Q000473:pathology*; D008099:Liver / Q000473:pathology; D008297:Male; D010179:Pancreas / Q000002:abnormalities* / Q000473:pathology; D013004:Somatostatin / Q000032:analysis
chemical_list: D007328:Insulin; D013004:Somatostatin; D005934:Glucagon