Primate neostriatal neurons containing tyrosine hydroxylase: immunohistochemical evidence.
We have detected, in monkey caudate nucleus and putamen, neuronal cell bodies containing tyrosine hydroxylase-like immunoreactivity, as revealed by peroxidase-antiperoxidase immunohistochemistry. Many of these cells are distributed in an outer rim of 1-2 mm throughout the anterior-posterior extent of the neostriatum near its borders with the corona radiata; others are embedded in the adjacent white matter, especially near the ventral putamen and nucleus accumbens. Light and electron microscopy indicate that they are small (8-12 micron), bipolar cells with large nuclei. Such neostriatal neurons, containing tyrosine hydroxylase-like immunoreactivity, number in the tens of thousands.
D000818:Animals; D003342:Corpus Striatum / Q000201:enzymology*; D007124:Immunoenzyme Techniques; D008252:Macaca fascicularis; D008254:Macaca nemestrina; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008854:Microscopy, Electron; D010215:Papio; D051381:Rats; D011919:Rats, Inbred Strains; D013045:Species Specificity; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism*
D014446:Tyrosine 3-Monooxygenase