Control of ciliary beat frequency in the gill of Mytilus--I. Activation of the lateral cilia by cyclic AMP.
The effect of cyclic AMP on the beat frequency of the lateral cilia on the gill of Mytilus edulis was investigated. Dibutyryl cyclic AMP (0.1 mM) weakly stimulated the cilia to beat. The activation was augmented by 1 mM theophylline. The cilia were hardly activated by cyclic AMP (0.1 mM) but a strong activation was observed when it was applied with saponin (0.0025-0.01% w/v) and theophylline (1 mM). The results suggest that cyclic AMP is involved in the mechanism of ciliary activation by 5-hydroxytryptamine.
D000818:Animals; D049872:Bivalvia / Q000502:physiology*; D003994:Bucladesine / Q000494:pharmacology; D002118:Calcium / Q000502:physiology; D002923:Cilia / Q000502:physiology*; D000242:Cyclic AMP / Q000502:physiology; D005880:Gills / Q000502:physiology; D009068:Movement; D010507:Periodicity; D012503:Saponins / Q000494:pharmacology; D013806:Theophylline / Q000494:pharmacology
D012503:Saponins; D003994:Bucladesine; D013806:Theophylline; D000242:Cyclic AMP; D002118:Calcium