title: Myc-1 is centromeric to the linkage group Ly-6--Sis--Gdc-1 on mouse chromosome 15.
abstract: A survey of wild mouse DNA with a c-myc exon 1 probe revealed a Taq I restriction fragment length polymorphism (RFLP) among Mus species. As a result of this Taq I RFLP, a cross between Mus musculus domesticus and BALB/cJ permitted the positioning of Myc-1 on chromosome 15 with respect to Ly-6, Sis, and Gdc-1. Compilation of the recombination frequency generated from this cross with published cytogenetic and plasma-cytoma somatic cell hybrid data suggests the following chromosome 15 orientation: centromere--Myc-1--Ly-6--Sis--Gdc-1--telomere. This gene order is consistent with conservation of man-mouse synteny.
mesh_terms: D000818:Animals; D000950:Antigens, Ly / Q000235:genetics*; D002503:Centromere / Q000032:analysis*; D002874:Chromosome Mapping; D002875:Chromosomes / Q000032:analysis*; D003433:Crosses, Genetic; D005091:Exons; D005260:Female; D008040:Genetic Linkage; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009857:Oncogenes; D012150:Polymorphism, Restriction Fragment Length; D011995:Recombination, Genetic
chemical_list: D000950:Antigens, Ly