Antiserum to scrapie-associated fibril protein cross-reacts with Spiroplasma mirum fibril proteins.
Protease-resistant fibril proteins purified from Spiroplasma mirum and from Creutzfeldt-Jakob disease-infected brain tissues reacted with antisera to scrapie-associated fibrils on Western immunoblot analysis. These data suggest that there are conformational similarities among spiroplasma proteins and infection-specific proteins of the transmissible spongiform encephalopathies.
D000818:Animals; D001426:Bacterial Proteins / Q000276:immunology*; D007562:Creutzfeldt-Jakob Syndrome / Q000276:immunology*; D003429:Cross Reactions; D006801:Humans; D007118:Immunoassay; D009419:Nerve Tissue Proteins / Q000276:immunology*; D018622:PrP 27-30 Protein; D013149:Spiroplasma / Q000276:immunology*
D001426:Bacterial Proteins; D009419:Nerve Tissue Proteins; D018622:PrP 27-30 Protein