title: Bipolar affective disorders linked to DNA markers on chromosome 11.
abstract: An analysis of the segregation of restriction fragment length polymorphisms in an Old Order Amish pedigree has made it possible to localize a dominant gene conferring a strong predisposition to manic depressive disease to the tip of the short arm of chromosome 11.
mesh_terms: D000293:Adolescent; D000328:Adult; D001714:Bipolar Disorder / Q000453:epidemiology / Q000208:ethnology / Q000235:genetics*; D002835:Christianity; D002880:Chromosomes, Human, Pair 11; D004247:DNA / Q000235:genetics; D005006:Ethnicity; D005819:Genetic Markers; D006801:Humans; D010375:Pedigree; D010414:Pennsylvania; D012150:Polymorphism, Restriction Fragment Length; D012068:Religion and Medicine
chemical_list: D005819:Genetic Markers; D004247:DNA