title: Enzyme activity in mice with transplantable leukemia.
abstract: Activity of cobalt activated acylase, gamma-glutamyltransferase, leucylaminopeptidase and alanylaminopeptidase in serum and liver of mice with transplantable leukemias (L1210, L1210/ara-C, L1210/CH3-G, AKSL-4, plasmacytoma ADJ-PC-5) were determined. Adenosinotriphosphatase, 5'-nucleotidase and alkaline phosphatase were histochemically localized in lymphatic nodes and spleen. Among the investigated enzymes the rise in serum activity of cobalt activated acylase and gamma-glutamyltransferase was demonstrated. A substantial increase of leucylaminopeptidase and alanylaminopeptidase was shown in the liver. A decrease in the histochemical reactions of all the studied enzymes was observed.
mesh_terms: D000251:Adenosine Triphosphatases / Q000097:blood; D000626:Aminopeptidases / Q000097:blood; D000818:Animals; D006651:Histocytochemistry; D006867:Hydrolases / Q000097:blood*; D007939:Leukemia L1210 / Q000097:blood / Q000201:enzymology; D007942:Leukemia, Experimental / Q000201:enzymology*; D008297:Male; D008565:Membrane Proteins / Q000378:metabolism; D051379:Mice; D008815:Mice, Inbred Strains; D009368:Neoplasm Transplantation; D005723:gamma-Glutamyltransferase / Q000097:blood
chemical_list: D008565:Membrane Proteins; D005723:gamma-Glutamyltransferase; D006867:Hydrolases; D000626:Aminopeptidases; D000251:Adenosine Triphosphatases