Comparative investigation of chlormethiazole and neuroleptic agents in the treatment of alcoholic delirium.
A retrospective study comparing the efficacy of chlormethiazole and neuroleptic agents showed that a mortality rate of 0% was associated with chlormethiazole treatment and 6% with neuroleptic treatment (P less than 0.005). Data from the literature support this result. Chlormethiazole treatment seems to be superior to the neuroleptic treatment of alcoholic delirium.
D000328:Adult; D000368:Aged; D000430:Alcohol Withdrawal Delirium / Q000188:drug therapy* / Q000401:mortality; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D002719:Chlormethiazole / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011604:Psychoses, Alcoholic / Q000188:drug therapy*; D012189:Retrospective Studies
D014150:Antipsychotic Agents; D002719:Chlormethiazole