Transforming activity of crude extract of pseudorabies virus-transformed cells.
Crude extract of pseudorabies virus (PRV)-transformed human (H-PR-1) cells induced transformation in human embryonic lung (HEL) cells. When the extract was removed, the acquired cell morphology remained unchanged, but the saturation density of cells was decreased. The transforming effect of the extract was neutralized with anti-PRV IgG.
D002472:Cell Transformation, Viral; D002478:Cells, Cultured; D011558:Herpesvirus 1, Suid; D006801:Humans; D010455:Peptides / Q000302:isolation & purification*; D015291:Transforming Growth Factors
D010455:Peptides; D015291:Transforming Growth Factors