title: Serum gastrin, insulin and somatostatin levels in normal and obese subjects before and after gastric banding.
abstract: The postprandial secretion of insulin, gastrin and somatostatin was studied in 23 extremely obese subjects and nine normal-weight controls after a liquid test meal. Apart from a significantly higher insulin level in the obese group, no significant intergroup difference was found. The effect of weight loss on the same hormones was studied in 18 patients 6 months after gastric banding. The mean weight loss during this period was 33 +/- 2.1 (SEM) kg. There was significant decrease in postprandial insulin secretion after gastric banding, but neither gastrin nor somatostatin levels were altered.
mesh_terms: D000328:Adult; D001835:Body Weight; D005260:Female; D005502:Food; D005755:Gastrins / Q000097:blood*; D006801:Humans; D007328:Insulin / Q000097:blood*; D008297:Male; D008722:Methods; D009767:Obesity, Morbid / Q000097:blood* / Q000628:therapy; D011863:Radioimmunoassay; D013004:Somatostatin / Q000097:blood*; D013270:Stomach / Q000601:surgery*
chemical_list: D005755:Gastrins; D007328:Insulin; D013004:Somatostatin