Dieldrin transformation to photodieldrin in liver and kidney of broiler.
Dieldrin, a potent residual insecticide and common contaminant of the environment, is metabolized in liver and kidney of broiler to photodieldrin, a photoisomer of dieldrin. This metabolite has by gas-liquid chromatography (g.l.c.) analysis a retention time different to the aldrin. The analysis by thin-layer chromatography (t.l.c.) of metabolite shows an Rf of 0.37. The i.r. (infra-red) spectrum shows the band corresponding to the epoxide ring (800-1300 cm-1) and does not show the characteristics bands of C = O (1800 cm-1) and ClC = CCl (1600 cm-1).
D000818:Animals; D001711:Biotransformation; D002645:Chickens / Q000378:metabolism*; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D004026:Dieldrin / Q000031:analogs & derivatives* / Q000378:metabolism*; D005260:Female; D007536:Isomerism; D007668:Kidney / Q000032:analysis / Q000378:metabolism*; D008099:Liver / Q000032:analysis / Q000378:metabolism*; D008297:Male; D013055:Spectrophotometry, Infrared; D014020:Tissue Extracts / Q000032:analysis
D014020:Tissue Extracts; C008892:photodieldrin; D004026:Dieldrin