title: Microdialysis measurement of oxytocin, aspartate, gamma-aminobutyric acid and glutamate release from the olfactory bulb of the sheep during vaginocervical stimulation.
abstract: Concentrations of oxytocin and amino acids were measured in microdialysis samples taken from the olfactory bulbs of 5 conscious, oestrogen-treated ewes before, during and after a 10-min period of vaginocervical stimulation. Results showed that vaginocervical stimulation induced significant increases in concentrations of oxytocin, aspartate, gamma-aminobutyric acid (GABA) and glutamate in dialysis samples. Concentrations of other amino acids measured were not affected. These findings show that vaginocervical stimulation produces significant changes in neurochemical release in the olfactory bulbs of sheep. Such changes may be involved in the induction of maternal behaviour of the olfactory recognition of offspring.
mesh_terms: D000818:Animals; D001224:Aspartic Acid / Q000378:metabolism*; D002584:Cervix Uteri / Q000294:innervation*; D003956:Dialysis; D005260:Female; D005971:Glutamates / Q000378:metabolism*; D018698:Glutamic Acid; D009830:Olfactory Bulb / Q000378:metabolism* / Q000502:physiology; D010121:Oxytocin / Q000378:metabolism*; D012756:Sheep; D014621:Vagina / Q000294:innervation*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
chemical_list: D005971:Glutamates; D001224:Aspartic Acid; D018698:Glutamic Acid; D010121:Oxytocin; D005680:gamma-Aminobutyric Acid