title: Adjunctive alprazolam for schizophrenia with panic anxiety: clinical observation and pathogenetic implications.
abstract: Seven patients with schizophrenia and panic attacks all showed marked improvement of positive and negative schizophrenic symptoms when alprazolam was openly added to antipsychotic medication. Panic attacks may identify alprazolam-responsive schizophrenic patients and may define a distinct pathophysiologic subgroup.
mesh_terms: D000293:Adolescent; D000328:Adult; D000525:Alprazolam / Q000627:therapeutic use*; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001008:Anxiety Disorders / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D004298:Dopamine / Q000502:physiology; D004359:Drug Therapy, Combination; D005239:Fear; D005260:Female; D006801:Humans; D008297:Male; D010200:Panic; D010865:Pilot Projects; D012559:Schizophrenia / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D012565:Schizophrenic Psychology
chemical_list: D014150:Antipsychotic Agents; D004298:Dopamine; D000525:Alprazolam