Evolutionary conservation of the human homologue of the yeast cell cycle control gene cdc2 and assignment of Cd2 to chromosome 10.
The human homologue of the fission yeast Schizosaccharomyces pombe cell cycle control gene cdc2 has been assigned to chromosome 10. DNA hybridization reveals that this gene is highly conserved in vertebrates. The human CDC2 gene probe detects a simple two-allele polymorphism in Taq1-digested DNA.
D000483:Alleles; D005075:Biological Evolution; D016203:CDC2 Protein Kinase; D002453:Cell Cycle; D002874:Chromosome Mapping; D002879:Chromosomes, Human, Pair 10; D005656:Fungal Proteins / Q000235:genetics*; D005796:Genes; D005800:Genes, Fungal; D006801:Humans; D010750:Phosphoproteins / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length; D004718:Saccharomycetales / Q000235:genetics*; D012568:Schizosaccharomyces / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D013045:Species Specificity
D005656:Fungal Proteins; D010750:Phosphoproteins; D016203:CDC2 Protein Kinase