title: [Failure of gastric lavage in severe drug poisoning. Value of esophagogastric fibroscopy].
abstract: A case is reported of massive drug self-poisoning (more than 200 pills associated with slices of oranges) in which repeated gastric lavage failed to empty the stomach. An attempt to split up the amalgamated pills, adherent to the gastric mucosa, by fibre-optic gastroscopy failed and a gastrotomy was required. Endoscopy together with gastric lavage is indicated in certain situations to quickly empty the stomach and so shorten the course of the poisoning. Indications are the large number of pills swallowed, a poor result of the treatment, a worsening of the clinical condition despite treatment, and three positive gastric toxicological assays within the first 24 h.
mesh_terms: D000639:Amitriptyline / Q000506:poisoning*; D014150:Antipsychotic Agents / Q000506:poisoning*; D004562:Electrocardiography; D005260:Female; D005751:Gastric Lavage; D005773:Gastroscopy; D006327:Heart Block / Q000209:etiology; D006801:Humans; D008140:Lorazepam / Q000506:poisoning*; D008875:Middle Aged; D010640:Phenothiazines / Q000506:poisoning*
chemical_list: D014150:Antipsychotic Agents; D010640:Phenothiazines; D000639:Amitriptyline; C028457:cyamemazine; D008140:Lorazepam
vernacular_title: Echec du lavage gastrique dans une intoxication médicamenteuse grave. Intérêt de la fibroscopie oeso-gastrique.