Regulatory decision making and the need for and the use of exposure data on pesticides determined to be teratogenic in test animals.
Major efforts have been made in the development of a system that takes the reviewer step-by-step by the use of the developmental toxicity and exposure assessment data to a recommended risk assessment and risk management position. Thereupon a set of regulatory decisions can be arrived at that are backed up by sound scientific analysis. Examples of pesticides that have been found to be teratogenic in animal testing are provided to demonstrate the process of use of exposure data in making risk assessment and management decisions.
D000818:Animals; D004353:Drug Evaluation, Preclinical / Q000379:methods; D006801:Humans; D009784:Occupational Diseases / Q000139:chemically induced / Q000517:prevention & control; D010575:Pesticides / Q000633:toxicity*; D012107:Research Design; D012306:Risk; D012869:Skin Absorption; D013723:Teratogens
D010575:Pesticides; D013723:Teratogens