title: Treatment of sex offenders with imaginal desensitization and/or medroxyprogesterone.
abstract: Thirty sex offenders were randomly allocated: 10 to receive medroxyprogesterone therapy (M), 10, imaginal desensitization (ID) and 10 both (ID + M). Twenty-four responded for one year though 3 subsequently relapsed. There were no significant differences in response to the 3 treatments. Four patients who did not respond to the initial treatment and the 3 who relapsed responded to further treatment. Most treated with M maintained heterosexual intercourse at pretreatment frequency. Self-reported reduction in anomalous sexual urges in patients receiving M correlated with reduced testosterone levels one month following treatment, demonstrating that the response was specific and validating the assessment by patients' self-reports. Where cost-effectiveness or time constraints are factors influencing treatment of sex offenders, one of these therapies warrants consideration.
mesh_terms: D000293:Adolescent; D000328:Adult; D001521:Behavior Therapy; D003131:Combined Modality Therapy; D003887:Desensitization, Psychologic; D006801:Humans; D007092:Imagination; D008297:Male; D008525:Medroxyprogesterone / Q000009:adverse effects / Q000627:therapeutic use*; D008875:Middle Aged; D010262:Paraphilic Disorders / Q000188:drug therapy / Q000628:therapy*; D012008:Recurrence; D012742:Sex Offenses; D013739:Testosterone / Q000097:blood
chemical_list: D013739:Testosterone; D008525:Medroxyprogesterone