Adjunctive alprazolam for schizophrenia with panic anxiety: clinical observation and pathogenetic implications.
Seven patients with schizophrenia and panic attacks all showed marked improvement of positive and negative schizophrenic symptoms when alprazolam was openly added to antipsychotic medication. Panic attacks may identify alprazolam-responsive schizophrenic patients and may define a distinct pathophysiologic subgroup.
D000293:Adolescent; D000328:Adult; D000525:Alprazolam / Q000627:therapeutic use*; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001008:Anxiety Disorders / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D004298:Dopamine / Q000502:physiology; D004359:Drug Therapy, Combination; D005239:Fear; D005260:Female; D006801:Humans; D008297:Male; D010200:Panic; D010865:Pilot Projects; D012559:Schizophrenia / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D012565:Schizophrenic Psychology
D014150:Antipsychotic Agents; D004298:Dopamine; D000525:Alprazolam