Adult T-cell leukemia following long-term remission from non-Hodgkin's lymphoma.
A female patient who had been initially diagnosed with non-Hodgkin's lymphoma (NHL) and achieved complete clinical remission with combined chemotherapy, developed overt adult T-cell leukemia (ATL) after 9 yr of disease-free survival. This is the first case of the development of ATL following the complete remission of NHL. Secondary malignant neoplasms are not well-documented in patients previously diagnosed with Hodgkin's disease. Although there have been a few reports concerning the occurrence of secondary malignancy in patients with non-Hodgkin's lymphoma (NHL), there has never been a documented case of ATL following long-term survival from NHL. Here, we report a case of typical adult T-cell leukemia (ATL) which occurred after 9 yr disease-free survival from NHL.
D001773:Blood Cells / Q000473:pathology; D006800:Deltaretrovirus Infections / Q000150:complications*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008228:Lymphoma, Non-Hodgkin / Q000097:blood / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008875:Middle Aged; D012074:Remission Induction; D013997:Time Factors