title: The gene for T11 (CD2) maps to chromosome 1 in humans and to chromosome 3 in mice.
abstract: The chromosomal locations of the human and murine T11 (CD2) gene have been determined. Using recently cloned cDNA to probe Southern blots of mouse X human and Chinese hamster X mouse somatic cell hybrids, we have localized the human T11 gene to chromosome 1 and the murine T11 gene to chromosome 3. Based on previously determined blocks of homology between human chromosome 1 and mouse chromosome 3, it is suggested that the human T11 gene may lie on the short arm of chromosome 1 proximal to p221. Thus, the T11 gene is not linked to any other genes for T cell markers that have been mapped to date.
mesh_terms: D000818:Animals; D018801:CD2 Antigens; D002352:Carrier Proteins / Q000235:genetics* / Q000302:isolation & purification; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D003001:Cloning, Molecular; D006224:Cricetinae; D003412:Cricetulus; D005796:Genes; D006801:Humans; D006822:Hybrid Cells / Q000032:analysis; D051379:Mice; D008805:Mice, Inbred A; D008807:Mice, Inbred BALB C; D009693:Nucleic Acid Hybridization; D011971:Receptors, Immunologic / Q000235:genetics* / Q000302:isolation & purification; D012689:Sequence Homology, Nucleic Acid
chemical_list: D018801:CD2 Antigens; D002352:Carrier Proteins; D011971:Receptors, Immunologic