title: Total intravenous anaesthesia for military surgery. A technique using ketamine, midazolam and vecuronium.
abstract: Ketamine and midazolam were used for induction of anaesthesia and by continuous intravenous infusion for maintenance to assess their suitability for use in a total intravenous anaesthetic technique in the management of battle casualties. Muscular relaxation was provided by vecuronium and the patients' lungs ventilated with air. Ketamine was infused at a rate of 2 mg/kg/hour. This was achieved by mixing ketamine 200 mg, midazolam 5 mg and vecuronium 12 mg in 50 ml normal saline. The rate of infusion of the mixture (ml/hour) was then equal to 50% of the body weight in kg. The technique proved to be simple, effective and versatile and should be adaptable for use in the management of battle casualties.
mesh_terms: D000293:Adolescent; D000328:Adult; D000771:Anesthesia, Intravenous / Q000379:methods*; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007649:Ketamine; D008297:Male; D008874:Midazolam; D008875:Middle Aged; D014673:Vecuronium Bromide; D014857:Warfare; D014947:Wounds and Injuries / Q000601:surgery*
chemical_list: D007649:Ketamine; D014673:Vecuronium Bromide; D008874:Midazolam