title: The mercury-203 method for evaluating metallothioneins: interference by copper, mercury, oxygen, silver and selenium.
abstract: Metallothioneins are low molecular weight proteins rich in sulfhydryl groups (cysteinyl) which readily bind various heavy metal cations, e.g. cadmium, copper, gold, mercury, silver and zinc. Mercury has a particular affinity for sulfhydryl groups and mercury-203 has been used as the basis of a rapid, sensitive, radiometric assay for metallothionein. The potential of 16 metals and oxygen for interfering with this test was examined. The mercury-203 test appears to be sensitive to the presence of copper, mercury, oxygen, selenium and silver.
mesh_terms: D000818:Animals; D049872:Bivalvia / Q000378:metabolism*; D003300:Copper / Q000032:analysis; D008628:Mercury / Q000032:analysis; D008631:Mercury Radioisotopes; D008668:Metallothionein / Q000032:analysis*; D010100:Oxygen / Q000032:analysis; D012643:Selenium / Q000032:analysis; D012834:Silver / Q000032:analysis
chemical_list: D008631:Mercury Radioisotopes; D012834:Silver; D003300:Copper; D008668:Metallothionein; D008628:Mercury; D012643:Selenium; D010100:Oxygen