title: The control of intra-ocular pressure during the induction of anaesthesia for emergency eye surgery. A high-dose vecuronium technique.
abstract: A technique of rapid sequence induction of anaesthesia for use in patients with penetrating eye injuries is described. This utilises a three maximal breaths method of pre-oxygenation, the intravenous injection of thiopentone and high dose vecuronium (0.2 mg/kg). Using the loss of eyelash reflex as the starting point for timing, all patients were intubated after 60 seconds without coughing and bucking. No postintubation increases in intra-ocular pressure were seen in 70% of patients and in no patient did the increase in intra-ocular pressure exceed 5 mmHg. After 3 minutes of apnoea, the minimum haemoglobin oxygen saturation was 94% with a mean value of 97.6%.
mesh_terms: D000768:Anesthesia, General / Q000379:methods*; D005131:Eye Injuries / Q000601:surgery; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D010100:Oxygen; D013874:Thiopental; D014673:Vecuronium Bromide / Q000008:administration & dosage*; D014950:Wounds, Penetrating / Q000601:surgery
chemical_list: D014673:Vecuronium Bromide; D013874:Thiopental; D010100:Oxygen