Detection of the antigen and antibodies to the eastern subtype of haemorrhagic fever with renal syndrome virus in small rodents in Slovakia.
Direct enzyme-linked immunosorbent assay (ELISA) was used for the demonstration of haemorrhagic fever with renal syndrome (HFRS) virus antigen in lung tissue of small rodents trapped in Eastern and Western Slovakia. The eastern subtype of HFRS virus antigen was demonstrated in the lungs of Apodemus agrarius and of the western subtype in the lungs of Microtus arvalis. Antibodies to HFRS virus antigen have been detected in Apodemus species (A. agrarius and A. flavicollis) in higher titres to the Eastern subtype.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D000956:Antigens, Viral / Q000032:analysis*; D003411:Arvicolinae / Q000382:microbiology*; D003604:Czechoslovakia; D004797:Enzyme-Linked Immunosorbent Assay; D006476:Orthohantavirus / Q000145:classification / Q000276:immunology*; D008168:Lung / Q000382:microbiology; D008297:Male; D009115:Muridae / Q000382:microbiology*
D000914:Antibodies, Viral; D000956:Antigens, Viral