[Relaxation and rapid filling of the left ventricle in essential hypertension during treatment with a non-selective beta blocker].
Some indices of relaxation and rapid filling were evaluated in the course of a six-month treatment with non-selective beta-blocker in 30 patients with hypertonic disease, (HD), degree II, with echocardiographically confirmed left-ventricular hypertrophy and normal systolic function. The phase analysis of the early diastole, performed according to Alvarez and Goodwin, reveals a progressive shortening of the period of isovolumetric relaxation and lengthening of the period of active suction with no change in the summed up period of rapid relaxation; the period of rapid filing is lengthened on account of the active suction. The evaluated via computer analysis (echo-computer--NIEMT-MA, Sofia) parameters of rapid filling of M-type echogram of left ventricle (maximum velocity of increase of left-ventricular dimension, mean velocity of fraction of rapid filling) increase progressively. The dynamics of the indices of diastolic function described, reflect the diminution of the restriction of ventricular filling and its shifting to the early diastole.
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000328:Adult; D005260:Female; D006352:Heart Ventricles; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D011412:Propanolamines / Q000494:pharmacology / Q000627:therapeutic use*; D011433:Propranolol / Q000494:pharmacology / Q000627:therapeutic use*
D000319:Adrenergic beta-Antagonists; D011412:Propanolamines; D011433:Propranolol; C025725:tobanum
Relaksatsiia i burzo pulnene na liavata kamera pri khipertonichna bolest v khoda na lechenieto s neselektiven beta-bloker.