[Therapeutic approach targeting the proteins involved in mechanisms of multidrug resistance].
Recently, the mechanisms of multidrug resistance have been partly elucidated. Based on these resistant mechanisms, therapeutic approaches targeting the proteins involved in the mechanisms of multidrug resistance are under investigation. These include therapies with monoclonal antibodies, drug resistant genes and agents interacting with the proteins of resistant tumor cells.
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D004351:Drug Resistance / Q000235:genetics; D006801:Humans; D066298:In Vitro Techniques; D008562:Membrane Glycoproteins / Q000235:genetics; D009369:Neoplasms / Q000188:drug therapy*
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000911:Antibodies, Monoclonal; D008562:Membrane Glycoproteins