Immunohistochemical and subcellular studies of aminopeptidase M localization in rat brain: microvessels and synaptic membranes.
A predominantly microvascular localization of aminopeptidase M (APM) was established both by immunohistochemistry and biochemical studies of isolated microvessels. In addition a high relative specific activity of APM was evidenced in fractions enriched in synaptic membranes.
D000626:Aminopeptidases / Q000276:immunology / Q000378:metabolism*; D000818:Animals; D000906:Antibodies; D001921:Brain / Q000166:cytology / Q000201:enzymology*; D018826:CD13 Antigens; D002560:Cerebrovascular Circulation; D007124:Immunoenzyme Techniques; D008833:Microcirculation / Q000201:enzymology; D051381:Rats; D013570:Synaptic Membranes / Q000201:enzymology* / Q000648:ultrastructure
D000906:Antibodies; D000626:Aminopeptidases; D018826:CD13 Antigens