Calcitonin induces hypercalcemia in grey mullet and immature freshwater and sea-water adapted rainbow trout.
1. Changes in plasma calcium levels, in response to salmon calcitonin injections, were studied in freshwater and sea-water adapted trout (Salmo gairdnerii) and in grey mullet (Chelon labrosus). 2. Low doses (0.1 ng sCT/100 g body weight) elicited hypercalcemia in the two species studied. 3. High doses (0.5 microgram) provoked hypocalcemia only in freshwater and sea-water adapted trout. 4. An hypercalcemic response appears as the primordial effects of CT injections, higher doses of CT leading to hypocalcemic effects.
D000064:Acclimatization; D000818:Animals; D002116:Calcitonin / Q000494:pharmacology*; D002118:Calcium / Q000097:blood*; D005618:Fresh Water; D006934:Hypercalcemia / Q000139:chemically induced*; D010473:Perciformes / Q000097:blood*; D012487:Salmonidae / Q000097:blood*; D012623:Seawater; D013045:Species Specificity; D014337:Trout / Q000097:blood*
D002116:Calcitonin; D002118:Calcium