[Proposal of a new analgesia test based on the observation of nociceptive behavior induced by electric stimulation of dental pulp in the rat].
Dental pulp was electrically stimulated in the awake rat. When the stimulus intensity was progressively increased the following four nociceptive reactions successively appeared: jaw opening reflex, scratching, head rotation, vocalization. The threshold of these four reactions was observed before and after administration of three antalgic drugs. No action of the three drugs was observed for the jaw opening reflex. However each drug showed different actions on the other three reactions.
D000698:Analgesia; D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D001583:Benzoxazoles; D003782:Dental Pulp / Q000187:drug effects / Q000502:physiology*; D004558:Electric Stimulation; D005897:Glafenine / Q000494:pharmacology; D008297:Male; D009020:Morphine / Q000494:pharmacology; D009619:Nociceptors / Q000187:drug effects / Q000502:physiology*; D010080:Oxazoles / Q000494:pharmacology; D023303:Oxazolidinones; D051381:Rats; D011919:Rats, Inbred Strains
D000700:Analgesics; D001583:Benzoxazoles; D010080:Oxazoles; D023303:Oxazolidinones; D005897:Glafenine; C043851:6-benzoyl benzoxazolinone; D009020:Morphine
Proposition d'un nouveau test algésimétrique fondé sur l'observation des comportements nociceptifs induits par la stimulation électrique de la pulpe dentaire chez le rat.