title: [Trials of immunostimulation of an antitoxic response with levamisole in the immunization of sheep with a combined clostridial vaccine].
abstract: Comparative investigations were carried out on the antibody level in test animals--sheep, vaccinated with a polyvaccine against C and D enterotoxemia and necrotic hepatitis as well as in combined application with Levamisol. It was found that with the use of the preparation the stimulation of immunogenesis with type D and necrotic hepatitis--type B antigens (included in the composition of the polyvaccine) was enhanced. No stimulation of immunogenesis with the type C specific antigen was found within the period of investigation. Immunity was better built up when the animals were treated with the combined product as compared with the controls, given the polyvaccine without Levamisol.
mesh_terms: D000276:Adjuvants, Immunologic; D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D001428:Bacterial Vaccines / Q000276:immunology*; D003013:Clostridium / Q000276:immunology*; D003016:Clostridium perfringens / Q000276:immunology; D004338:Drug Combinations; D004341:Drug Evaluation / Q000662:veterinary; D007114:Immunization / Q000379:methods / Q000662:veterinary*; D007978:Levamisole / Q000627:therapeutic use*; D012756:Sheep / Q000276:immunology*; D013773:Tetramisole / Q000627:therapeutic use*
chemical_list: D000276:Adjuvants, Immunologic; D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines; D004338:Drug Combinations; D007978:Levamisole; D013773:Tetramisole
vernacular_title: Opiti za imunostimulatsiia na antitoksichniia otgovor posredstvom levamizol pri imunizirane na ovtse s kombinirana klostridialna vaksina.