title: Differential expression of an alpha-tubulin gene during the development of Physarum polycephalum.
abstract: The expression of an alpha-tubulin gene (altB1 (N alpha Tu) [(1987) J. Mol. Biol. 193, 427-438]) of Physarum polycephalum (strain CLdAXE) was found to be governed by a developmental switch since mRNA transcripts were detected, by S1 nuclease analysis, in the plasmodial but not the amoebal phase of the life-cycle. The conclusion that the altB1 (N alpha Tu) allele codes for a plasmodial specific alpha-tubulin isotype is supported by recent amino acid sequence data.
mesh_terms: D000199:Actins / Q000096:biosynthesis; D000483:Alleles; D000595:Amino Acid Sequence; D005656:Fungal Proteins / Q000096:biosynthesis / Q000235:genetics*; D005786:Gene Expression Regulation; D005800:Genes, Fungal; D010804:Physarum / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D011061:Poly A / Q000032:analysis; D012331:RNA, Fungal / Q000032:analysis; D012333:RNA, Messenger / Q000032:analysis; D014404:Tubulin / Q000096:biosynthesis / Q000235:genetics*
chemical_list: D000199:Actins; D005656:Fungal Proteins; D012331:RNA, Fungal; D012333:RNA, Messenger; D014404:Tubulin; D011061:Poly A