title: Aphakic cystoid macular edema secondary to betaxolol therapy.
abstract: Since the approval of timolol for the treatment of open-angle glaucoma, beta-adrenergic blocking drugs have replaced epinephrine, a pure alpha and beta agonist, as the treatment of choice for glaucoma in aphakic patients. To date, there have been no reports of cystoid macular edema secondary to timolol, a non-selective beta-adrenergic blocker that apparently has little intrinsic sympathomimetic activity. Betaxolol is a new beta-adrenergic receptor blocker that preferentially blocks beta 1 receptors. We report a case of angiographically proven cystoid macular edema secondary to betaxolol therapy that resolved after discontinuation and recurred after a monocular therapeutic trial.
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000009:adverse effects* / Q000627:therapeutic use; D000368:Aged; D000369:Aged, 80 and over; D015784:Betaxolol; D002387:Cataract Extraction; D005260:Female; D005902:Glaucoma, Open-Angle / Q000188:drug therapy; D006801:Humans; D008269:Macular Edema / Q000139:chemically induced*; D011183:Postoperative Complications / Q000188:drug therapy; D011412:Propanolamines / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000319:Adrenergic beta-Antagonists; D011412:Propanolamines; D015784:Betaxolol