title: [Effects of aspartic acid in the electroreceptors of the skate].
abstract: To identify the afferent transmitter in ampullary electroreceptors of the marine skates effects of L-aspartic acid (L-ASP) were examined using bath application of the drug. Perfusion of the basal membrane with L-ASP produced an increase in activity in most experiments (threshold concentrations 10(-7) M). L-GLU and L-ASP were identical in their ability to activate the afferents. In the presence of presynaptic blockade (high Mg2+) bath application of L-ASP restored the resting activity, suggesting a postsynaptic action of L-ASP. The results are consistent with the view that L-GLU, L-ASP or a related compound may play a role in afferent transmission in the ampullae of Lorenzini of skates.
mesh_terms: D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D001224:Aspartic Acid / Q000494:pharmacology*; D004555:Electric Fish / Q000502:physiology*; D005971:Glutamates / Q000494:pharmacology; D018698:Glutamic Acid; D012679:Sense Organs / Q000187:drug effects*; D011984:Sensory Receptor Cells / Q000187:drug effects; D012860:Skates, Fish / Q000502:physiology*; D013569:Synapses / Q000187:drug effects; D009435:Synaptic Transmission / Q000187:drug effects
chemical_list: D005971:Glutamates; D001224:Aspartic Acid; D018698:Glutamic Acid
vernacular_title: Effekty asparaginovoĭ aminokilsoty v élektroretseptorakh skatov.