A mouse homeo box-containing gene maps near a developmental mutation.
Mouse genes containing homeo box domains are predicted to fulfill important functions in embryogenesis. Using recombinant inbred mouse strains, we have mapped a mouse gene which contains a homeo box with homology to the Drosophila engrailed gene. This gene maps to mouse chromosome 1 near or at the dominant hemimelia locus which is a known mouse developmental mutation.
D000818:Animals; D002874:Chromosome Mapping; D004247:DNA / Q000235:genetics; D004331:Drosophila melanogaster; D005801:Genes, Homeobox; D051379:Mice; D008815:Mice, Inbred Strains; D008817:Mice, Mutant Strains; D009154:Mutation; D012150:Polymorphism, Restriction Fragment Length
D004247:DNA