[Action of antihistaminic agents in patients with various heart pathologies undergoing surgical treatment].
Clinical observations and experimental studies enabled the authors to show that sensitivity of patients with rheumatic heart diseases to antihistaminic drugs is not always constant. It depends on pH value of the medium and blood concentration of calcium ions. It is advisable to include antihistaminic drugs in combination with colloid and crystalloid blood substitutes with regard to pH of the medium into the complex of agents for pre-, intra- and postoperative medication.
D000293:Adolescent; D000328:Adult; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D006634:Histamine H1 Antagonists / Q000627:therapeutic use*; D006801:Humans; D007430:Intraoperative Care; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000188:drug therapy* / Q000503:physiopathology / Q000601:surgery; D008946:Mitral Valve Stenosis / Q000188:drug therapy* / Q000503:physiopathology / Q000601:surgery; D011182:Postoperative Care; D011292:Premedication; D012214:Rheumatic Heart Disease / Q000188:drug therapy* / Q000503:physiopathology / Q000601:surgery
D006634:Histamine H1 Antagonists
Issledovanie deĭstviia protivogistaminnykh sredstv u bol'nykh s razlichnoĭ patologieĭ serdtsa pri khirurgicheskom lechenii.