title: [Mid-term results of a double-blind study comparing metipranolol to timolol in the treatment of primary open-angle glaucoma].
abstract: A study on 26 patients with chronic angle glaucoma was completed after 17 weeks. The IOP was satisfactorily stabilized on patients treated with Metipranolol drops. In the Timolol group, the IOP rose again after the 9th week and, at the completion of the study, the difference between the averages of the two groups is significant. No systemic effect was noted as well in the Metipranolol group as in the Timolol group.
mesh_terms: D004311:Double-Blind Method; D005902:Glaucoma, Open-Angle / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D014290:Metipranolol / Q000009:adverse effects / Q000627:therapeutic use*; D009883:Ophthalmic Solutions; D011412:Propanolamines / Q000627:therapeutic use*; D013997:Time Factors; D013999:Timolol / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D009883:Ophthalmic Solutions; D011412:Propanolamines; D013999:Timolol; D014290:Metipranolol
vernacular_title: Résultats d'une étude à moyen terme à double insu comparant le métipranolol au timolol dans le traitement du glaucome primitif à angle ouvert.