title: Single thalamic dopaminergic neurons project to both the neocortex and spinal cord.
abstract: Cells in the rat subparafascicular thalamic nucleus (Spf) belonging to the diencephalic A11 cell group, were immunohistochemically stained with antibodies against tyrosine hydroxylase (TH) and dopamine itself. Employing a combination of retrograde fluorescent double-labeling and TH immunofluorescence techniques, we revealed the existence of dopaminergic Spf cells, giving rise to collateral projections to the neocortex and spinal cord.
mesh_terms: D000818:Animals; D004298:Dopamine / Q000032:analysis*; D005456:Fluorescent Dyes; D005625:Frontal Lobe / Q000033:anatomy & histology* / Q000166:cytology; D007150:Immunohistochemistry; D008297:Male; D009434:Neural Pathways / Q000033:anatomy & histology; D051381:Rats; D011919:Rats, Inbred Strains; D013116:Spinal Cord / Q000033:anatomy & histology* / Q000166:cytology; D013787:Thalamic Nuclei / Q000032:analysis / Q000033:anatomy & histology* / Q000166:cytology; D014446:Tyrosine 3-Monooxygenase / Q000032:analysis
chemical_list: D005456:Fluorescent Dyes; D014446:Tyrosine 3-Monooxygenase; D004298:Dopamine