Vecuronium in the management of tetanus. Is it the muscle relaxant of choice?
Two cases of severe tetanus admitted to ITU with muscle rigidity and convulsions and needed mechanical ventilation had a continuous infusion of vecuronium as muscle relaxant. The cardiovascular changes of the two patients are described. It is concluded that vecuronium because of its minimal cardiovascular effects is the relaxant of choice in the management of severe tetanus.
D000368:Aged; D002319:Cardiovascular System / Q000187:drug effects; D003131:Combined Modality Therapy; D003422:Critical Care; D003975:Diazepam / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013742:Tetanus / Q000188:drug therapy* / Q000628:therapy; D014673:Vecuronium Bromide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
D014673:Vecuronium Bromide; D003975:Diazepam