title: Changes in neurotransmitter amino acids content in several CNS areas from aggressive and non-aggressive bull strains.
abstract: Neurotransmitter amino acid levels (glutamate, aspartate, GABA, and glycine) of crude synaptosomal fractions from several non-limbic CNS areas (pons, ventral tegmentum, midbrain reticular formation, fastigial nucleus of cerebellum, posterior colliculus and anterior colliculus) showed significant differences between aggressive Spanish fighting-bull and non-aggressive Friesian strains. The most unequal distribution was observed in neurotransmitter amino acids, while the non-transmitter amino acids (serine, isoleucine, leucine, threonine and alanine) showed minor and uneven changes. The results suggest a possible relationship between changes in amino acid neurotransmitter levels and the aggressive behavior observed in the aggressive breed.
mesh_terms: D000374:Aggression / Q000502:physiology*; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001224:Aspartic Acid / Q000032:analysis*; D001933:Brain Stem / Q000032:analysis*; D002417:Cattle; D002531:Cerebellum / Q000032:analysis; D005260:Female; D005971:Glutamates / Q000032:analysis*; D018698:Glutamic Acid; D005998:Glycine / Q000032:analysis*; D008636:Mesencephalon / Q000032:analysis; D011149:Pons / Q000032:analysis; D013574:Synaptosomes / Q000032:analysis; D005680:gamma-Aminobutyric Acid / Q000032:analysis*
chemical_list: D000596:Amino Acids; D005971:Glutamates; D001224:Aspartic Acid; D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid; D005998:Glycine