title: Effect of neurotensin on the smooth muscle of the chicken crop.
abstract: 1. The effect of neurotensin was studied in the isolated smooth muscle of the chicken crop. 2. This peptide induced concentration-dependent (10(-10)-10(-8) mol/l) contractions of muscle strips. 3. The response to neurotensin was not modified after incubation of the preparation with atropine, indomethacin, naloxone and tetrodotoxin. The neurotensin-exerted contractions are therefore probably myogenic. 4. These properties of neurotensin indicate a possible role for this peptide in the control of crop motility.
mesh_terms: D000818:Animals; D001285:Atropine / Q000494:pharmacology; D002645:Chickens; D004305:Dose-Response Relationship, Drug; D007213:Indomethacin / Q000494:pharmacology; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects*; D009270:Naloxone / Q000494:pharmacology; D009496:Neurotensin / Q000494:pharmacology*; D013779:Tetrodotoxin / Q000494:pharmacology
chemical_list: D009270:Naloxone; D009496:Neurotensin; D013779:Tetrodotoxin; D001285:Atropine; D007213:Indomethacin