title: A quantitative assessment of the reactivity of the fatty alcohols with cetrimide using immersion calorimetry.
abstract: The reactivity of the fatty alcohols with cetrimide has been quantitatively assessed using immersion calorimetry. In all cases the reaction was endothermic i.e. it had a positive enthalpy. For the n-alcohols the reactivity, as evaluated by the rate of enthalpy change, decreased with increasing chain length although branching on the tetradecanol and hexadecanol resulted in a higher reactivity. Adding 1-octadecanol to 1-hexadecanol resulted in an increased reactivity rising to a maximum for mixtures containing 20-40% w/w 1-octadecanol. The results have been interpreted in terms of the polymorphic form of the alcohol.
mesh_terms: D002151:Calorimetry / Q000379:methods; D000077286:Cetrimonium; D002593:Cetrimonium Compounds; D004339:Drug Compounding; D005233:Fatty Alcohols; D000644:Quaternary Ammonium Compounds; D013816:Thermodynamics
chemical_list: D002593:Cetrimonium Compounds; D005233:Fatty Alcohols; D000644:Quaternary Ammonium Compounds; D000077286:Cetrimonium