Large cell mycosis fungoides at the tumor stage. Unusual T8, T4, T6 phenotypic expression.
We report a case of mycosis fungoides in a 52-year-old woman with a huge skin tumor on her thigh in which the predominant cells were lymphoblastic and histiocytic large cells. The neoplastic cells showed strong suppressor and helper T-cell subset markers, and were partially positive for the cortical thymocyte (OKT6) subset marker.
D000951:Antigens, Neoplasm / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000276:immunology / Q000473:pathology*; D010641:Phenotype; D012878:Skin Neoplasms / Q000276:immunology / Q000473:pathology*; D013601:T-Lymphocytes / Q000145:classification / Q000276:immunology*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology; D013848:Thigh
D000951:Antigens, Neoplasm; D000954:Antigens, Surface