title: Advances in the diagnosis and treatment of medullary thyroid carcinoma.
abstract: Medullary thyroid carcinoma accounts for 5 to 10 per cent of all thyroid malignancies and may occur in a familial or a sporadic pattern. This article reviews the authors' experience with 200 patients with medullary thyroid carcinoma and outlines the recent advances made in our understanding of the biochemical properties of these cancer cells and the relationship of different tumor markers to prognosis.
mesh_terms: D002116:Calcitonin / Q000097:blood; D002272:Carcinoembryonic Antigen / Q000032:analysis; D002277:Carcinoma / Q000145:classification / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008207:Lymphatic Metastasis; D008722:Methods; D009377:Multiple Endocrine Neoplasia / Q000145:classification; D037981:Neck Dissection; D011379:Prognosis; D013961:Thyroid Gland / Q000378:metabolism / Q000473:pathology; D013964:Thyroid Neoplasms / Q000145:classification / Q000175:diagnosis* / Q000601:surgery; D013965:Thyroidectomy
chemical_list: D002272:Carcinoembryonic Antigen; D002116:Calcitonin