Tension responses to increased hydrostatic pressure in glycerinated rabbit psoas muscle fibres.
A method developed to study the effect of increased hydrostatic pressure on the isometric tension of a single muscle fibre is described and experiments done at room temperature (18-22 degrees C) on glycerinated rabbit psoas muscle fibres are presented. Increase of pressure (range 1-10 MPa) caused little change in tension transducer response when a muscle fibre was relaxed. However, there was a reversible depression of isometric tension with an increase of pressure when a fibre was maximally calcium-activated or in rigor; the depression was around 15% for active tension and 30% for rigor tension, for an increase of pressure of 10 MPa (ca. 100 atm).
D000818:Animals; D005990:Glycerol; D006874:Hydrostatic Pressure; D066298:In Vitro Techniques; D007537:Isometric Contraction; D009119:Muscle Contraction; D009132:Muscles / Q000502:physiology*; D011312:Pressure; D011817:Rabbits
D005990:Glycerol