Multiple endocrine neoplasia, type III.
Multiple oral plexiform neuromas in a 14-year-old white girl prompting screening of the patient with respect to the multiple endocrine neoplasia (MEN) type-III syndrome, verified the existence of a thyroid medullary carcinoma and the diagnosis MEN-type III. Total thyroidectomy was performed, but extensive tumour infiltration prevented radical tumour excision. The condition being relatively infrequent, the important life-saving role of dental practitioners and oral surgeons in its recognition and early diagnosis is emphasized.
D000293:Adolescent; D002277:Carcinoma / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009377:Multiple Endocrine Neoplasia / Q000175:diagnosis / Q000235:genetics / Q000473:pathology*; D009455:Neurofibroma / Q000473:pathology; D013964:Thyroid Neoplasms / Q000473:pathology; D014062:Tongue Neoplasms / Q000473:pathology