Analytical profile of the new diuretic beta-blocking agent tienoxolol hydrochloride.
Physicochemical properties, i.e. elemental analysis, spectra (NMR, MS, IR, UV), solubilities, pKa, partition coefficient, melting point, HPLC, and data on purity and stability of ethyl 2-(3-[(1,1-dimethylethyl)amino]-2-hydroxy-propoxy)-5-[(2- thienylcarbonyl)amino]benzoate hydrochloride (tienoxolol), a new drug with antihypertensive properties are reported.
D000319:Adrenergic beta-Antagonists / Q000032:analysis*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004355:Drug Stability; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D011208:Powders; D011412:Propanolamines / Q000032:analysis*; D012995:Solubility; D012996:Solutions; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D000319:Adrenergic beta-Antagonists; D011208:Powders; D011412:Propanolamines; D012996:Solutions; C056983:tienoxolol