Encephalitis in dogs associated with a batch of canine distemper (Rockborn) vaccine.
During a period of seven months in 1982-83 cases of postvaccinal encephalitis were recorded in dogs in various parts of Britain after the administration of a particular batch of combined distemper/hepatitis vaccine. Detailed investigations of one of these cases revealed that the distemper component was responsible and the vaccine virus was recovered from the brain of an affected dog.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D001921:Brain / Q000382:microbiology / Q000473:pathology; D004196:Disease Outbreaks / Q000662:veterinary*; D004217:Distemper Virus, Canine / Q000276:immunology* / Q000302:isolation & purification; D004283:Dog Diseases / Q000209:etiology* / Q000473:pathology; D004285:Dogs; D004673:Encephalomyelitis, Acute Disseminated / Q000473:pathology / Q000662:veterinary*; D005455:Fluorescent Antibody Technique; D013116:Spinal Cord / Q000473:pathology; D014611:Vaccination / Q000662:veterinary; D014765:Viral Vaccines / Q000009:adverse effects*
D000914:Antibodies, Viral; D014765:Viral Vaccines