title: LH-RH treatment for cryptorchidism. Randomized study and 10-year follow-up results.
abstract: A randomized study (LH-RH treatment or surgery) of 60 cryptorchid children between 2 and 9 years of age was performed. Testicular biopsy obtained in all patients undergoing orchiopexy showed histological changes compatible with cryptorchidism. Only maldescended and non-retractile testes were treated. LH-RH treatment was successful in 59% of the patients. Ten years later, 52% of testes remained descended. Thus LH-RH treatment is effective in achieving descent of true cryptorchid testes.
mesh_terms: D002648:Child; D002675:Child, Preschool; D003456:Cryptorchidism / Q000188:drug therapy* / Q000601:surgery; D005500:Follow-Up Studies; D007987:Gonadotropin-Releasing Hormone / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011897:Random Allocation; D013737:Testis / Q000601:surgery; D013997:Time Factors
chemical_list: D007987:Gonadotropin-Releasing Hormone