[A case of malignant neuroleptic syndrome with rhabdomyolysis and a therapeutic trial using physostigmine].
We report the case of a 22-year-old schizophrenic patient who developed a neuroleptic malignant syndrome under treatment with Benperidol, Levomepromazin and Biperiden. Clinical signs were: fever, rigidity, altered consciousness and rhabdomyolysis of hip-abductors. Intravenous injection of physostigmine led to clearing of consciousness, whereas there seemed to be no impact on fever and rigidity.
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D009459:Neuroleptic Malignant Syndrome / Q000188:drug therapy*; D010830:Physostigmine / Q000627:therapeutic use*; D012206:Rhabdomyolysis / Q000139:chemically induced / Q000188:drug therapy*; D012563:Schizophrenia, Paranoid / Q000188:drug therapy*
D014150:Antipsychotic Agents; D010830:Physostigmine
Ein Fall von malignem neuroleptischem Syndrom mit Rhabdomyolyse und Therapieversuch mit Physostigmin.