Partial trisomy chromosome 5 cosegregating with schizophrenia.
Schizophrenia was associated with a distinct autosomal abnormality in two related mildly dysmorphic individuals. The finding of cosegregation of schizophrenia and a partial trisomy of chromosome 5 in the family suggests a potential location of a gene or genes linked to schizophrenia.
D000328:Adult; D002869:Chromosome Aberrations / Q000150:complications*; D025063:Chromosome Disorders; D002878:Chromosomes, Human, Pair 1; D002895:Chromosomes, Human, Pair 5; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D010641:Phenotype; D012559:Schizophrenia / Q000235:genetics*; D014314:Trisomy