Treatment-resistant mania with primary hypothyroidism: a case of recovery after levothyroxine.
A manic-depressive woman was unresponsive to treatment with lithium and neuroleptics during a period of mania. Additional levothyroxine treatment of her primary hypothyroidism resulted in rapid and complete recovery from her mania.
D014150:Antipsychotic Agents / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000150:complications / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000150:complications / Q000188:drug therapy* / Q000209:etiology; D008094:Lithium / Q000009:adverse effects / Q000627:therapeutic use; D008875:Middle Aged; D013974:Thyroxine / Q000627:therapeutic use*
D014150:Antipsychotic Agents; D008094:Lithium; D013974:Thyroxine