Pulmonary reactions induced by drugs: a clinical compendium.
With the increasing number of drugs, the list of agents which are capable of inducing pulmonary reactions continues to lengthen. This article is a compendium of presently available information on drug induced pulmonary reactions which we have found clinically useful. We have divided the drugs in groups on the basis of two features, pharmacologic actions and type of pulmonary reactions. A total of 109 drugs are cited. Categories of pharmacologic actions include cytotoxic drugs, analgesic and antirheumatic drugs, antimicrobial agents, vasoactive drugs, tranquilizers, anticonvulsants, antidepressants, antiarrhythmics, oral antidiabetics and a group of miscellaneous drugs. Type of pulmonary reactions include pulmonary eosinophilia, bronchoconstriction, acute interstitial pulmonary disease, mediastinic involvement, pleural effusion, pulmonary hypertension, pulmonary calcifications, pulmonary infections and drugs reported to cause drug-induced Systemic Lupus Erythematosus.
D000319:Adrenergic beta-Antagonists / Q000009:adverse effects; D000700:Analgesics / Q000009:adverse effects; D000890:Anti-Infective Agents / Q000009:adverse effects; D000893:Anti-Inflammatory Agents / Q000009:adverse effects; D000903:Antibiotics, Antineoplastic / Q000009:adverse effects; D004342:Drug Hypersensitivity; D006801:Humans; D008171:Lung Diseases / Q000139:chemically induced*; D004364:Pharmaceutical Preparations / Q000145:classification; D012130:Respiratory Hypersensitivity / Q000209:etiology; D013566:Sympathomimetics / Q000009:adverse effects
D000319:Adrenergic beta-Antagonists; D000700:Analgesics; D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D000903:Antibiotics, Antineoplastic; D004364:Pharmaceutical Preparations; D013566:Sympathomimetics