title: Differential diagnosis of motoneurone disease from other neurological conditions.
abstract: Analysis of 422 patients with clinical diagnoses of motoneurone disease (MND), multiple sclerosis, cervical spondylosis with myelopathy, or stroke, from two referral centres, suggested a simple four-step algorithm for diagnosing MND. The algorithm provided a 98% sensitivity (true positive diagnosis) and 86% specificity, and therefore gives a baseline for diagnostic criteria suitable for use in clinical research of MND.
mesh_terms: D000465:Algorithms; D002561:Cerebrovascular Disorders / Q000175:diagnosis; D002574:Cervical Vertebrae; D003936:Diagnosis, Computer-Assisted; D003937:Diagnosis, Differential; D006801:Humans; D009046:Motor Neurons; D009103:Multiple Sclerosis / Q000175:diagnosis; D009468:Neuromuscular Diseases / Q000175:diagnosis*; D013128:Spinal Osteophytosis / Q000175:diagnosis