title: [Characteristics of morphogenesis of cryptorchism in childhood].
abstract: The main morphological features of undescended testes in children of 2-14 years old were incomplete cytodifferentiation of Sertoli cells (absence of transition of Sa = Sb cells into Sc type), reduced number of spermatogonia and dystrophic changes in germ cells. Intense progressive sclerosis developed in the interstitium and walls of seminiferous tubules. The dark Sertoli cells were described as a distinct cell type for the first time. The results of the morphological study indicated that cryptorchism should be surgically corrected during the first two years of life.
mesh_terms: D000293:Adolescent; D002454:Cell Differentiation; D002648:Child; D002675:Child, Preschool; D003456:Cryptorchidism / Q000473:pathology*; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009024:Morphogenesis; D012671:Seminiferous Tubules / Q000473:pathology / Q000648:ultrastructure; D012708:Sertoli Cells / Q000473:pathology / Q000648:ultrastructure; D013093:Spermatogonia / Q000473:pathology* / Q000648:ultrastructure; D013094:Spermatozoa / Q000473:pathology*; D013737:Testis / Q000473:pathology* / Q000648:ultrastructure
vernacular_title: Osobennosti morfogeneza kriptorkhizma v detskom vozraste.