Evaluation of gamma-glutamyl transpeptidase-to-creatinine ratio from spot samples of urine supernatant, as an indicator of urinary enzyme excretion in dogs.
gamma-Glutamyl transpeptidase activity was measured accurately in canine urine supernatant without gel filtration and was relatively stable at 4 C for at least 4 days after collection. The urinary gamma-glutamyl transpeptidase-to-creatinine ratio in spot samples was simple and quick to measure and was correlated with the 24-hour enzyme excretion. However, the usefulness of this ratio may be limited by within-day variation, and a questionable theoretical basis for its validity.
D000818:Animals; D002850:Chromatography, Gel; D003404:Creatinine / Q000652:urine*; D004285:Dogs / Q000652:urine*; D005260:Female; D008297:Male; D005723:gamma-Glutamyltransferase / Q000652:urine*
D003404:Creatinine; D005723:gamma-Glutamyltransferase