Coronary artery surgery with patient's lungs as oxygenator.
The use of the patient's own lungs as oxygenator was assessed during coronary artery bypass grafting in 20 patients. This technique maintained the circulation and provides excellent oxygenation, and the lungs did not intrude on the operative field. Blood damage as assessed by platelet function and lung sequestration was less than that reported with other forms of bypass. No microbubbles were produced, since there was no artificial blood/air interface. Complement activation, as assessed by amount of white-cell sequestration in the lungs, was also lower than that reported in other forms of bypass. There were no major complications attributable to the technique. Apart from being substantially cheaper than conventional cardiopulmonary bypass, the use of the patient's lungs as oxygenator offers the potential advantage of reduced trauma to the blood and merits further consideration.
D000328:Adult; D000368:Aged; D001026:Coronary Artery Bypass; D005112:Extracorporeal Circulation / Q000379:methods*; D006801:Humans; D008168:Lung / Q000502:physiology*; D008875:Middle Aged