Effect of ethylenediaminetetraacetic acid (EDTA) on acute mercury poisoning of toad.
Studies have been carried out on the ability of EDTA (CaNa2-ethylenediaminetetraacetate) to offset the acute toxicity of mercuric chloride. The lethality of mercury was tested in female Bufo regularis species (Amphibia) which were given EDTA immediately after the Hg2+ injection. The results show that the inherent toxicity of the EDTA-mercury complex is sufficiently high for it to be ineffective as an antidote.
D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000097:blood; D001798:Blood Proteins / Q000378:metabolism; D002025:Bufonidae; D004492:Edetic Acid / Q000627:therapeutic use*; D005260:Female; D007770:L-Lactate Dehydrogenase / Q000097:blood; D007928:Lethal Dose 50; D008630:Mercury Poisoning / Q000097:blood / Q000188:drug therapy*
D001798:Blood Proteins; D004492:Edetic Acid; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D001663:Bilirubin