title: Essential fatty acid status in southern Thai preschool children.
abstract: Essential fatty acid (EFA) status was assessed in 15 Southern Thai preschool children. The mean (+/- SD) serum linoleate (18:2 n-6), arachidonate (20:4 n-6), linolenate (18:3 n-3), eicosapentaenoate (20:5 n-3), and docosahexaenoate (22:6 n-3) percentages in the preschool children were 21.7 +/- 4.0, 6.0 +/- 1.2, 0.4 +/- 0.1, 1.2 +/- 0.8, and 4.4 +/- 1.3, respectively. Since EFA composition of total serum lipids in healthy children are not available and age and sex do not largely influence these parameters, the results of the preschool children were compared with those of 10 healthy Bangkok adults. The corresponding figures of the aforementioned fatty acids in adults were 34.9 +/- 8.5, 4.6 +/- 1.5, 0.8 +/- 0.4, 0.5 +/- 0.4, and 1.6 +/- 0.8, respectively. The data indicate linoleate and linolenate depletion in the preschool children. This was due to their low fat intake and lack of consumption of vegetable oil rich in linoleic and linolenic acids. Their high serum arachidonate percentage was probably due to the increased conversion of 18:2 n-6 to 20:4 n-6 in the presence of linolenate depletion. The significantly higher serum 20:5 n-3 and 22:6 n-3 percentages in the preschool children should be due to direct consumption of these two n-3 fatty acids from fish intake.
mesh_terms: D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000097:blood; D002675:Child, Preschool; D004032:Diet; D004281:Docosahexaenoic Acids / Q000097:blood; D015118:Eicosapentaenoic Acid / Q000097:blood; D005228:Fatty Acids, Essential / Q000097:blood*; D005260:Female; D006801:Humans; D019787:Linoleic Acid; D008041:Linoleic Acids / Q000097:blood / Q000172:deficiency*; D008042:Linolenic Acids / Q000097:blood / Q000172:deficiency*; D008055:Lipids / Q000097:blood; D008297:Male; D013785:Thailand; D017962:alpha-Linolenic Acid
chemical_list: D001095:Arachidonic Acids; D005228:Fatty Acids, Essential; D008041:Linoleic Acids; D008042:Linolenic Acids; D008055:Lipids; D017962:alpha-Linolenic Acid; D004281:Docosahexaenoic Acids; D016718:Arachidonic Acid; D019787:Linoleic Acid; D015118:Eicosapentaenoic Acid