Comparison of the genetic determinant coding for the S-fimbrial adhesin (sfa) of Escherichia coli to other chromosomally encoded fimbrial determinants.
DNA probes specific for different regions of the S-fimbrial adhesin (sfa) determinant were constructed and hybridized with DNA sequences coding for P (F8 and F13), mannose-sensitive hemagglutinating type 1 (F1A), and F1C fimbriae. While the sfa and F1C DNA determinants exhibited homology along their entire lengths, the P-fimbrial and type 1-fimbrial determinants exhibited homology to regions of the sfa cluster responsible for the control of transcription and, to a minor extent, to regions coding for proteins involved in biogenesis and/or adhesion of the fimbriae and for the N-terminal part of the fimbrillin subunit.
D018830:Adhesins, Escherichia coli; D001422:Bacterial Adhesion; D001426:Bacterial Proteins / Q000235:genetics*; D002874:Chromosome Mapping; D004262:DNA Restriction Enzymes; D004926:Escherichia coli / Q000235:genetics*; D010861:Fimbriae, Bacterial; D005798:Genes, Bacterial; D005809:Genes, Regulator; D006388:Hemagglutinins / Q000235:genetics; D012689:Sequence Homology, Nucleic Acid
D018830:Adhesins, Escherichia coli; D001426:Bacterial Proteins; D006388:Hemagglutinins; D004262:DNA Restriction Enzymes