[Animal experiment studies on improving ischemia tolerance of the testis].
The reactions of the germinative testicular epithelium after definite ischemia periods were studied in rats. Using heparin the testicular ischemia tolerance has already been prolonged; this can be distinctly improved by adding alphareceptor blockers. The consequences of a 30 min and 2 h period of testicular ischemia are nearly eliminated by the described medicamentous combination. The experimental results show that at present the use of heparin and alpha-receptor blockers seems to be the best way, to extend the ischemia tolerance during autotransplantation of testicles.
D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology*; D000818:Animals; D004359:Drug Therapy, Combination; D006493:Heparin / Q000494:pharmacology*; D007511:Ischemia / Q000473:pathology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012039:Regional Blood Flow / Q000187:drug effects; D012670:Seminiferous Epithelium / Q000098:blood supply; D013091:Spermatogenesis / Q000187:drug effects; D013737:Testis / Q000098:blood supply*
D000317:Adrenergic alpha-Antagonists; D006493:Heparin
Tierexperimentelle Untersuchung zur Verbesserung der Ischämietoleranz des Hodens.