title: Bridge peptide is a cleavage product of pro-dynorphin processing in the rat anterior pituitary.
abstract: Bridge peptide, the sequence of amino acids which joins alpha-neo-endorphin and dynorphin A 1-17, was determined to exist as a free molecule in the rat anterior pituitary. Gel filtration chromatography revealed the presence of the free peptide as well as a high molecular weight intermediate of 8-9 kilodaltons.
mesh_terms: D000818:Animals; D004399:Dynorphins / Q000031:analogs & derivatives* / Q000378:metabolism; D004745:Enkephalins / Q000235:genetics* / Q000378:metabolism; D008297:Male; D008970:Molecular Weight; D010903:Pituitary Gland, Anterior / Q000378:metabolism*; D011498:Protein Precursors / Q000235:genetics* / Q000378:metabolism; D011499:Protein Processing, Post-Translational; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D004745:Enkephalins; D011498:Protein Precursors; C045486:dynorphin bridge peptide; D004399:Dynorphins; C033660:preproenkephalin