title: [Eosinophilic granuloma. Risk of fracture and rare site].
abstract: The eosinophilic granuloma of bone, Letterer-Siwe's disease and Hand-Schüller-Christian's disease are integrated under the conception Histiocytosis X. The same patho-histological findings, especially on bone and the observation that the 3 diseases can change one into the other are the reason for this conception. In the past the very different prognosis of the 3 diseases was the reason for difficulties of the classification and the therapy. In Letterer-Siwe's disease with bad prognosis and HSC with uncertain prognosis conservative therapy is mostly indicated. The eosinophilic granuloma in monotopic and polytopic localisation normally requires surgical procedure usually the excision of a specimen for the diagnosis. In special localisations with the fracture or the possibility of a fracture operative procedure with resection, bone grafting and osteosynthesis in order to get bone stability are indicated. 2 cases with special localisation are described.
mesh_terms: D016025:Bone Transplantation; D002648:Child; D002968:Clavicle / Q000293:injuries*; D004803:Eosinophilic Granuloma / Q000601:surgery*; D005260:Female; D005265:Femoral Neck Fractures / Q000601:surgery*; D005593:Fracture Fixation, Internal; D005598:Fractures, Spontaneous / Q000601:surgery*; D006801:Humans; D008875:Middle Aged
vernacular_title: Das eosinophile Granulom. Frakturgefährdung und seltene Lokalisation.