Bipolar affective disorders linked to DNA markers on chromosome 11.
An analysis of the segregation of restriction fragment length polymorphisms in an Old Order Amish pedigree has made it possible to localize a dominant gene conferring a strong predisposition to manic depressive disease to the tip of the short arm of chromosome 11.
D000293:Adolescent; D000328:Adult; D001714:Bipolar Disorder / Q000453:epidemiology / Q000208:ethnology / Q000235:genetics*; D002835:Christianity; D002880:Chromosomes, Human, Pair 11; D004247:DNA / Q000235:genetics; D005006:Ethnicity; D005819:Genetic Markers; D006801:Humans; D010375:Pedigree; D010414:Pennsylvania; D012150:Polymorphism, Restriction Fragment Length; D012068:Religion and Medicine
D005819:Genetic Markers; D004247:DNA