title: Experimental double infection with Coxiella burnetii and tick-borne encephalitis virus in Dermacentor reticulatus ticks.
abstract: Experimental parenteral inoculation of Dermacentor reticulatus ticks with the rickettsia Coxiella burnetii (C.b.) and tick-borne encephalitis (TBE) virus resulted in a generalized rickettsial and viral infection, irrespective of whether the agents were given simultaneously or by a 7 days interval apart. Both agents multiplied intensively in ticks, C.b. being detectable predominantly in cytoplasmic vacuoles and TBE virus mostly in the endoplasmic reticulum.
mesh_terms: D000818:Animals; D003381:Coxiella / Q000502:physiology* / Q000648:ultrastructure; D003870:Dermacentor / Q000382:microbiology*; D004669:Encephalitis Viruses, Tick-Borne / Q000502:physiology* / Q000648:ultrastructure; D005260:Female; D005455:Fluorescent Antibody Technique; D006458:Hemolymph / Q000382:microbiology; D008854:Microscopy, Electron; D013987:Ticks / Q000382:microbiology*