The venom of the wasp Campsomeris sexmaculata (F.) blocks synaptic transmission in insect CNS.
1. The action of the venom of the wasp Campsomeris sexmaculata on the insect CNS has been studied using the cercal nerve-giant interneuron preparation of the sixth abdominal ganglion of the cockroach. 2. The venom blocks synaptic transmission either transiently (at low concentration) or for a long time (at higher concentration), and causes a permanent depolarization of the neuron with a delay. 3. The venom does not affect directly the axonal excitability.
D000818:Animals; D001514:Bee Venoms / Q000494:pharmacology*; D005260:Female; D008564:Membrane Potentials / Q000187:drug effects; D010526:Periplaneta; D009435:Synaptic Transmission / Q000187:drug effects*; D014862:Wasp Venoms / Q000494:pharmacology*; D014863:Wasps
D001514:Bee Venoms; D014862:Wasp Venoms