Prevention of HTLV-I transmission through the breast milk by a freeze-thawing process.
Fifteen human breast milk samples obtained from mothers seropositive for human T-cell lymphotropic virus type-I (HTLV-I) antigen were kept frozen overnight at -20 degrees. Each milk sample was then co-cultivated with cord lymphocytes obtained from 15 anti-HTLV-I antibody-negative mothers. No HTLV-I antigen-positive cells were detected among the cord lymphocytes subjected to co-cultivation. These results suggest that thawing of frozen breast milk may prevent HTLV-I transmission from mother to child via breast milk.
D000956:Antigens, Viral / Q000032:analysis; D006800:Deltaretrovirus Infections / Q000517:prevention & control / Q000635:transmission*; D005260:Female; D005615:Freezing; D015488:HIV Antigens; D006801:Humans; D008214:Lymphocytes / Q000382:microbiology; D008895:Milk, Human / Q000382:microbiology*; D016685:Mitomycin; D008937:Mitomycins / Q000494:pharmacology; D011247:Pregnancy
D000956:Antigens, Viral; D015488:HIV Antigens; D008937:Mitomycins; D016685:Mitomycin