Epididymal and vas deferens immaturity in cryptorchidism.
Cryptorchidism is associated with impaired spermatogenesis and, at times, sterility. Early orchiopexy has been advocated as a possible means to prevent spermatogenic impairment and infertility in patients with cryptorchidism. This retrospective study is derived from data obtained from 74 cases that were observed during a period of approximately 10 years at our hospital. Particular attention was devoted to epididymal and vas deferens histological status. Of the 47 epididymides and vas deferens examined only 2 epididymides and 2 vas deferens showed histological maturity. The remainder showed varying degrees of immaturity that additionally correlated, when testicular tissue was available, with the presence of unfavorable testicular histological findings. Cryptorchidism is associated with changes in the gonads and spermatic duct system.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003456:Cryptorchidism / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D004822:Epididymis / Q000254:growth & development* / Q000473:pathology; D005854:Germ Cells / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D009919:Orchiectomy; D013737:Testis / Q000473:pathology; D014649:Vas Deferens / Q000254:growth & development* / Q000473:pathology