The effect of handcream on the antibacterial activity of chlorhexidine gluconate.
A series of handwashing experiments compared the residual effect on Escherichia coli of non-medicated soap, chlorhexidine detergent followed by an anionic handcream, chlorhexidine detergent followed by a non-ionic handcream and chlorhexidine detergent alone. Handcreams containing an anionic emulsifying agent reduced the antibacterial effect of chlorhexidine.
D002710:Chlorhexidine / Q000031:analogs & derivatives* / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects*; D004983:Ethanolamines / Q000494:pharmacology; D005079:Excipients / Q000494:pharmacology; D006235:Hand Disinfection; D006801:Humans
D004983:Ethanolamines; D005079:Excipients; C009546:triethanolamine; C010882:chlorhexidine gluconate; D002710:Chlorhexidine