Perinatal hypoxia and hepatic cell function in preterm and full term newborn infants.
Gamma-glutamyl transpeptidase activity and the serum concentration of lipoprotein-x, indirect bilirubin and total bile acids were measured in 28 preterm and 24 full term newborn infants, with or without hypoxia, at the postnatal age 3-4 days. Those preterm and full term babies who suffered from hypoxia had increased mean lipoprotein-x, bilirubin, total bile acid concentration and gamma-glutamyl transpeptidase activity in comparison to that of controls, but the differences were not significant statistically. Clinical implications of the results are briefly discussed.
D001238:Asphyxia Neonatorum / Q000097:blood / Q000503:physiopathology*; D001647:Bile Acids and Salts / Q000097:blood; D001663:Bilirubin / Q000097:blood; D001724:Birth Weight; D005260:Female; D005311:Fetal Hypoxia / Q000503:physiopathology*; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000097:blood / Q000503:physiopathology*; D008073:Lipoprotein-X / Q000097:blood; D008099:Liver / Q000503:physiopathology*; D011247:Pregnancy; D005723:gamma-Glutamyltransferase / Q000097:blood
D001647:Bile Acids and Salts; D008073:Lipoprotein-X; D005723:gamma-Glutamyltransferase; D001663:Bilirubin