title: Evidence of inadequate humidification of inspired gas during artificial ventilation of newborn babies in the British Isles.
abstract: Data on routine humidifier settings used in respiratory support for newborn babies were obtained from 242 neonatal units in the British Isles. For each of the most commonly used humidifiers inspired gas humidity was measured under routine clinical conditions with an electronic hygrometer. Most endotracheally intubated babies breathe inspired gas of well below physiological humidity (44 mg H2O/l) and many below the minimum recommended for adults by the British Standards Institution (33 mg H2O/l). Inadequate humidification could contribute to several complications of artificial ventilation in newborn babies by inhibiting mucociliary clearance.
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D006813:Humidity / Q000009:adverse effects*; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000628:therapy*; D007442:Intubation, Intratracheal; D012121:Respiration, Artificial / Q000592:standards; D006113:United Kingdom; D012122:Ventilators, Mechanical / Q000009:adverse effects*