Microscopic split-skin grafts: a new technique for 30-fold expansion.
Split skin was diced into 200 microns squares for use as a graft for large granulating wounds in pigs. "Diced" skin expanded 26-fold to give healing rates virtually identical with those obtainable with meshed split skin, despite a ten-fold difference in the area of donor skin used. The technique has been successfully applied in five patients with venous ulcers and seems to be a simple alternative to tissue culture for grafting extensive wounds.
D000818:Animals; D001684:Biological Dressings; D005069:Evaluation Studies as Topic; D006801:Humans; D008722:Methods; D011897:Random Allocation; D016038:Skin Transplantation; D013526:Surgical Mesh; D013552:Swine; D014184:Transplantation, Homologous; D014647:Varicose Ulcer / Q000601:surgery; D014945:Wound Healing