title: [Double-blind study on the effects of famotidine on bronchial tone and on expectoration].
abstract: A double blind test using famotidine and a placebo was conducted on 14 patients with hypersecretory, chronic bronchitis. No other drug treatment was given during the test or in the ten days preceding it. VC, FEV1, Sgaw and daily excrete volume were measured before the test and 7, 14 and 21 days after it began. The data collected indicate that H2 receptors have no influence on bronchial calibre or secretions.
mesh_terms: D000328:Adult; D001980:Bronchi / Q000187:drug effects*; D001991:Bronchitis / Q000503:physiopathology*; D004311:Double-Blind Method; D015738:Famotidine; D005260:Female; D005541:Forced Expiratory Volume; D006635:Histamine H2 Antagonists / Q000494:pharmacology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013183:Sputum / Q000378:metabolism*; D013844:Thiazoles / Q000494:pharmacology*; D014797:Vital Capacity / Q000187:drug effects
chemical_list: D006635:Histamine H2 Antagonists; D013844:Thiazoles; D015738:Famotidine
vernacular_title: Studio in doppio cieco sugli effetti della famotidina sul tono bronchiale e sull'espettorazione.