[Validity of post-proline splitting dipeptidyl aminopeptidase activities in the cerebrospinal fluid for neurologic and psychiatric diagnosis].
The dipeptidyl-peptidase activity of 650 liquores cerebrospinalis was obtained by means of the substrate Gly-Pro-NHNp (Gly-Pro-4-nitroanilid) at pHs of 5.5 and 7.4. In comparison with a reference collective, the suitability of the method as a supplementary liquor parameter in neurological psychiatric diagnosis was examined. The introduction of the measurement at pH 7.4 can be particularly recommended for the distinguishing of bacterial and nonbacterial meningitis.
D018819:Dipeptidyl Peptidase 4; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases / Q000134:cerebrospinal fluid*; D006801:Humans; D007700:Kinetics; D001523:Mental Disorders / Q000175:diagnosis* / Q000201:enzymology; D009422:Nervous System Diseases / Q000175:diagnosis* / Q000201:enzymology
D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; D018819:Dipeptidyl Peptidase 4
Die Validität der postprolinspaltenden Dipeptidyl-aminopeptidase-Aktivitäten im Liquor cerebrospinalis für die neurologisch-psychiatrische Diagnostik.