title: Measurement of six enzymes with the Kodak DTSC Module, a physician's office analyzer.
abstract: We evaluated the performance of the Kodak DTSC Module for determination of alanine aminotransferase (ALT; EC 2.6.1.2), aspartate aminotransferase (2.5.1.2), alkaline phosphatase (3.1.3.1), creatine kinase (2.7.3.2), gamma-glutamyltransferase (2.3.2.2), and lactate dehydrogenase (1.1.1.27). The DTSC is a "special chemistry" accessory for the DT60 analyzer; the same multilayer film technology as that of the Ektachem 700 is used. The overall precision, assessed over a three-month period with two serum-based quality control materials, ranged from 2.2 to 8.0%. DTSC results for patients' specimens correlated well with those by the Technicon RA-1000 analyzer. The performance of the analyzer in linearity and interference studies was satisfactory for clinical use. The DTSC is simple to operate and has no technique-dependent step; it should be useful for the physician's office laboratory.
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D019883:Alkyl and Aryl Transferases; D001322:Autoanalysis / Q000295:instrumentation*; D001663:Bilirubin; D003402:Creatine Kinase / Q000097:blood; D004798:Enzymes / Q000097:blood*; D006454:Hemoglobins; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008055:Lipids / Q000097:blood; D014166:Transferases / Q000097:blood; D005723:gamma-Glutamyltransferase / Q000097:blood
chemical_list: D004798:Enzymes; D006454:Hemoglobins; D008055:Lipids; D007770:L-Lactate Dehydrogenase; D014166:Transferases; D005723:gamma-Glutamyltransferase; D019883:Alkyl and Aryl Transferases; C022737:thiamin pyridinylase; D000410:Alanine Transaminase; D003402:Creatine Kinase; D000469:Alkaline Phosphatase; D001663:Bilirubin