Human T-cell lymphotropic virus type I infection in neonates.
One hundred twenty-eight serum samples, collected from infants transfused at the neonatal care unit of Kyushu University Hospital, Fukuoka, Japan, were tested for the presence of antibody to human T-cell lymphotropic virus type I (HTLV-I) by the enzyme-linked immunosorbent assay and the indirect immunofluorescence test. Three of 128 were positive for anti-HTLV-I antibody. The three seropositive patients had received 62, 82, and 1160 mL of transfused blood. These patients did not receive any transfusion thereafter. In addition, no anti-HTLV-I antibodies were detected in the sera of their mothers and siblings. These data suggested that HTLV-I infection is one of the transfusion-associated complications in neonates.
D000914:Antibodies, Viral / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D017977:Deltaretrovirus / Q000276:immunology*; D006800:Deltaretrovirus Infections / Q000276:immunology / Q000635:transmission*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D065227:Transfusion Reaction
D000914:Antibodies, Viral