A transmission delay and the effect of temperature at the triadic junction of skeletal muscle.
The coupling process at the triadic junctions in skeletal muscle fibres is characterized by a significant latency between the depolarization of the transverse tubular membrane and the release of Ca from the sarcoplasmic reticulum. This time interval, the triadic delay, is sufficiently long to allow for the participation of a chemical process. The strong temperature dependence of the triadic delay (Q10 near 2.7) suggests that a sequence of chemical steps may link the electrical signal in the T-tubules to the opening of Ca channels in the terminal cisternae of the sarcoplasmic reticulum.
D000818:Animals; D002118:Calcium / Q000502:physiology; D004396:Coloring Agents; D066298:In Vitro Techniques; D007700:Kinetics; D008564:Membrane Potentials; D009119:Muscle Contraction; D009132:Muscles / Q000502:physiology* / Q000648:ultrastructure; D011892:Rana catesbeiana; D012508:Sarcolemma / Q000502:physiology*; D012519:Sarcoplasmic Reticulum / Q000502:physiology; D013696:Temperature
D004396:Coloring Agents; D002118:Calcium