title: [Stimulation and inhibition of uterine contractions from the modern viewpoint].
abstract: We know close to nothing why preterm or adterm delivery in human being starts. Either it is the breakdown of mechanisms protecting the pregnancy when it is time for the baby to flee the no more adequate surrounding of the uterus, or the activation of substances starting uterine contractions. Most probable is the interaction between oxytocin and prostaglandines which leads to the onset of labour; the influence of the fetus on this procedure is discussed. Stimulation of contractions: Oxytocin given as infusion with or without foregoing priming by locally applied prostaglandines (exact supervision of uterine motility and the well-being of the fetus by CTG) and/or amniotomy. Infusions of Prostaglandines always cause uterine contractions ending with the expulsion of the fetus. Inhibition of uterine contractility: In cases of threatening premature delivery before during and after intraabdominal operations and fetal distress during term delivery nowadays Betamimetics are given. The application of alcohol is reserved for special cases.
mesh_terms: D000318:Adrenergic beta-Agonists / Q000627:therapeutic use; D000428:Alcohol Drinking; D002584:Cervix Uteri / Q000187:drug effects; D003131:Combined Modality Therapy; D005260:Female; D005323:Fetal Monitoring / Q000379:methods; D006801:Humans; D007751:Labor, Induced / Q000379:methods*; D007752:Obstetric Labor, Premature / Q000517:prevention & control*; D010121:Oxytocin / Q000627:therapeutic use; D011247:Pregnancy; D011453:Prostaglandins / Q000627:therapeutic use; D014590:Uterine Contraction / Q000187:drug effects*
chemical_list: D000318:Adrenergic beta-Agonists; D011453:Prostaglandins; D010121:Oxytocin
vernacular_title: Wehenstimulierung und Wehenhemmung aus neuerer Sicht.