title: [Morphologic examination of the urothelium after irradiation with laser energy].
abstract: The energy of a Nd-YAG laser (1,064 nm wave length, 8 ns pulse duration) was used to irradiate the urothelium of the ureter or bladder and kidney parenchyma in pigs. Single pulse energy was 50-120 mJ with a 20-Hz repetition rate. The horizontal laser beam was reflected 90 degrees down by a 100% mirror and with a specially designed apparatus focussed on the surface of the tissue. Laser light from a quartz glass fiber was also focussed directly onto the tissue. Urothelium and kidney parenchyma were irradiated in 7 pigs. Tissue samples were examined histologically and raster electron microscopically 2, 4, 8 and 12 days after irradiation. No macroscopic lesion could be found. Maximum energy caused a small cone of 40 micron depth. No thermic effects or necrosis resulted, so that no harm is to be expected with unintentional irradiation.
mesh_terms: D000818:Animals; D004727:Endothelium / Q000528:radiation effects; D007668:Kidney / Q000528:radiation effects; D053685:Laser Therapy; D007834:Lasers; D008096:Lithotripsy / Q000379:methods; D017602:Lithotripsy, Laser; D008854:Microscopy, Electron; D013552:Swine; D014513:Ureter / Q000473:pathology / Q000528:radiation effects*; D001743:Urinary Bladder / Q000473:pathology / Q000528:radiation effects*
vernacular_title: Morphologische Untersuchungen des Urothels nach Einwirkung intensiver Nanosekunden-Laserpulse.