title: Temperature-dependent transcriptional regulation of expression of fimbriae in an Escherichia coli strain isolated from a child with severe enteritis.
abstract: Escherichia coli 469-3 synthesizes fibrillar fimbriae at 37 degrees C, but not at 18 degrees C, which promote its adherence to human colonocytes. RNA homologous with a cloned fragment of the strain 469-3 chromosome necessary for normal expression of fimbriae was virtually undetectable in bacteria grown at 18 degrees C, indicating that environmental temperature affects expression by regulating transcription.
mesh_terms: D001422:Bacterial Adhesion; D004751:Enteritis / Q000382:microbiology*; D004926:Escherichia coli / Q000235:genetics*; D010861:Fimbriae, Bacterial; D005786:Gene Expression Regulation; D005798:Genes, Bacterial; D006388:Hemagglutinins / Q000235:genetics*; D006801:Humans; D012333:RNA, Messenger / Q000235:genetics; D013696:Temperature; D014158:Transcription, Genetic
chemical_list: D006388:Hemagglutinins; D012333:RNA, Messenger