title: Behavioural and combined therapy in panic states.
abstract: This review will focus only on those paradigms for treatment of panic states with agoraphobia. Until recently the behaviour therapy literature has completely ignored panic disorder and has focused exclusively on the agoraphobic aspect of this syndrome. To summarize the behavioural therapy of panic disorder and agoraphobia, it appears that exposure is in the short run the most effective behavioural paradigm in agoraphobia. However, when contrasted with cognitive approaches it does not appear to be as effective in the treatment of panic disorder. In conclusion, it is unclear whether we can speak of antiphobic medications. Certainly studies of imipramine, chlomipramine, monoamine oxidase inhibitors, and alprazolam have demonstrated an anti-panic affect of medications and a subsequent improvement in phobic avoidance. However, when exposure is not made a part of the treatment, there is a much poorer resolution and a tendancy for the patient to relapse.
mesh_terms: D000379:Agoraphobia / Q000628:therapy*; D001008:Anxiety Disorders / Q000628:therapy*; D001521:Behavior Therapy; D003071:Cognition / Q000187:drug effects; D003131:Combined Modality Therapy; D003887:Desensitization, Psychologic; D005239:Fear / Q000187:drug effects; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use; D010200:Panic / Q000187:drug effects; D010624:Phenelzine / Q000627:therapeutic use; D010698:Phobic Disorders / Q000628:therapy*
chemical_list: D010624:Phenelzine; D007099:Imipramine