title: Actinomyces adsorption mediated by type-1 fimbriae.
abstract: Monospecific antibody against the type-1 fimbriae of Actinomyces viscosus T14V reacted with 12 strains of A. viscosus (serotype 2), 12 strains of A. naeslundii (serotype 2 or serotype 3), but not with 11 serotype 1 strains of A. naeslundii. All strains positive for the type-1 fimbrial antigen adsorbed strongly to saliva-treated hydroxyapatite, and in many instances (18 of 24 strains) this interaction was inhibited by the monospecific antibody. These findings strongly suggest that only those strains of actinomyces which possess type-1 fimbriae adhere to the tooth surfaces, and that these fimbriae constitute the principal adhesin involved in this interaction.
mesh_terms: D000190:Actinomyces / Q000145:classification / Q000648:ultrastructure*; D000268:Adhesiveness; D000327:Adsorption; D000942:Antigens, Bacterial; D017886:Durapatite; D010861:Fimbriae, Bacterial / Q000276:immunology / Q000502:physiology*; D006801:Humans; D006882:Hydroxyapatites; D012463:Saliva / Q000502:physiology; D013499:Surface Properties
chemical_list: D000942:Antigens, Bacterial; D006882:Hydroxyapatites; D017886:Durapatite