title: [Changes in the health state of schizophrenic patients in neuroleptic therapy].
abstract: The state of health of 135 schizophrenic patients was examined during therapy with a nigrostriatal (Haloperidol) and a mesolimbic (Clozapin) neuroplegic drug, and compared with the situation during treatment without neuroplegics. Among the methods used was the state of health scale of von Zerssen; the neuroleptic threshold was tested using Haase's handwriting test. There was evidence that the patient's health was primarily affected, but individual differential treatment with neuroplegics produced a significant improvement in this important respect. Contrary to Haase, we noticed nothing to convince us of a link between the antipsychotic efficacy of the neuroplegics under investigation and the neuroleptic threshold.
mesh_terms: D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001294:Attitude to Health; D003024:Clozapine / Q000627:therapeutic use; D004409:Dyskinesia, Drug-Induced / Q000209:etiology; D006220:Haloperidol / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D009048:Motor Skills / Q000187:drug effects; D012559:Schizophrenia / Q000188:drug therapy*; D012565:Schizophrenic Psychology
chemical_list: D014150:Antipsychotic Agents; D003024:Clozapine; D006220:Haloperidol
vernacular_title: Befindlichkeitsänderungen schizophren Erkrankter unter neuroleptischer Therapie.