Transmissibility of human immunodeficiency virus in haemophilic and non-haemophilic children living in a private school in France.
In a study of the transmissibility of human immunodeficiency virus (HIV) in haemophilic and non-haemophilic children living together in a boarding school in France, half of the haemophilic children had seroconverted by the end of a 3-year study period. By contrast none of the non-haemophilic children seroconverted. All children had had close casual contact, some of them for several years. Hepatitis B virus (HBV) markers detected in all polytransfused haemophiliacs were found in 4 of 20 control children in the school, whereas all healthy youngsters living with their families were HBV negative. This study adds support to the theory that transmissibility of HIV among casual contacts is low and that there is no reason to exclude HIV-antibody carriers from communities.
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology / Q000635:transmission*; D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D004340:Drug Contamination; D005164:Factor IX / Q000627:therapeutic use; D005169:Factor VIII / Q000627:therapeutic use; D005602:France; D015483:HIV Antibodies; D006467:Hemophilia A / Q000150:complications* / Q000276:immunology / Q000628:therapy; D006515:Hepatitis B virus / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007223:Infant; D007231:Infant, Newborn; D008214:Lymphocytes / Q000145:classification; D008297:Male; D012111:Residence Characteristics; D012189:Retrospective Studies
D000914:Antibodies, Viral; D015483:HIV Antibodies; D007074:Immunoglobulin G; D005169:Factor VIII; D005164:Factor IX