title: [Reactogenic properties of a DTP vaccine with a reduced antigen dosage].
abstract: The reactogenic properties of batches of adsorbed DPT vaccine with the normal content of antigens and with the content of diphtheria and tetanus toxoids reduced, respectively, to 10 Lf and 5 BU per immunization dose have been studied under the conditions of a controlled epidemiological trial. The reduced antigenic content of adsorbed DPT vaccine decreased the number of vaccinal reactions 1.8 times, as well as the intensity of their manifestations.
mesh_terms: D000942:Antigens, Bacterial / Q000008:administration & dosage*; D001886:Bordetella pertussis / Q000276:immunology*; D003017:Clostridium tetani / Q000276:immunology*; D003353:Corynebacterium diphtheriae / Q000276:immunology*; D004168:Diphtheria Toxoid / Q000008:administration & dosage / Q000009:adverse effects*; D015721:Diphtheria-Tetanus-Pertussis Vaccine; D004338:Drug Combinations / Q000008:administration & dosage / Q000009:adverse effects; D004341:Drug Evaluation; D006801:Humans; D007117:Immunization, Secondary; D007223:Infant; D007844:Latvia; D010567:Pertussis Vaccine / Q000008:administration & dosage / Q000009:adverse effects*; D013745:Tetanus Toxoid / Q000008:administration & dosage / Q000009:adverse effects*; D014505:Urban Population
chemical_list: D000942:Antigens, Bacterial; D004168:Diphtheria Toxoid; D015721:Diphtheria-Tetanus-Pertussis Vaccine; D004338:Drug Combinations; D010567:Pertussis Vaccine; D013745:Tetanus Toxoid
vernacular_title: Reaktogennye svoĭstva AKDS-vaktsiny so snizhennoĭ antigennoĭ nagruzkoĭ.