title: [The enzyme diagnosis of liver involvement in meningococcal infection].
abstract: A complex of blood enzymes (AST, ALT, AP, GTT) was studied in 84 patients with generalized forms of MI. The study showed that signs of liver involvement were noted in 15.4% of the patients on the 1st day of disease. Laboratory signs of cytolysis and cholestasis were revealed in most examinees on the 7th-15th day of disease during a dynamic follow-up. The most noticeable syndromes were revealed in young patients (30 persons) with brain edema (42.2%). Primary liver involvement (i. e. noted on admission to hospital) in 6 patients was associated with MI toxic effects, in 7 patients--with a severe concomitant pathology of the pulmonary and cardiovascular system. Delayed liver involvement was detected in 55.3% of the young patients and in half of the elderly patients. It was established that a course of disease was accompanied by the affection of many organs from the first days complicating the interpretation of enzymological data therefore requiring combined enzymological investigations.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D004796:Clinical Enzyme Tests; D005966:Glucuronidase / Q000097:blood; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis* / Q000209:etiology; D008585:Meningitis, Meningococcal / Q000150:complications / Q000175:diagnosis; D008589:Meningococcal Infections / Q000150:complications / Q000175:diagnosis*; D008590:Meningoencephalitis / Q000150:complications / Q000175:diagnosis; D008875:Middle Aged; D018805:Sepsis / Q000150:complications / Q000175:diagnosis; D013997:Time Factors; D005723:gamma-Glutamyltransferase / Q000097:blood
chemical_list: D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D005966:Glucuronidase
vernacular_title: Enzimodiagnostika porazheniĭ pecheni pri meningokokkovoĭ infektsii.