title: Incidence of retroviruses in some Brazilian groups.
abstract: The prevalence of human T lymphotropic virus type I (HTLV-I) and human immunodeficiency virus (HIV) antibodies was evaluated in Brazil among 116 aboriginal Indians living in a pre-Amazonian region, and in 44 patients with haematological malignant disorders being treated in Rio de Janeiro. Screening for the presence of antibodies to HIV was performed routinely for 17,224 blood donors at the National Cancer Institute, Rio de Janeiro, from January 1986 to May 1987. The results demonstrated that HIV infection was not endemic among Brazilian Indians, as none of them had antibodies to HIV, in contrast with the population of Rio de Janeiro, which showed a high prevalence (0.34%) of positivity among normal individuals. In a small group of patients with haematological disease only one with acute lymphoblastic leukaemia proved to be HIV-positive, the infection having been acquired through previous blood transfusion. None of the serum samples reacted with HTLV-I, including those of 17 non-Hodgkin's lymphoma patients. HTLV-I infection does not seem to be endemic in this country, but further large scale studies are necessary, especially in patients with haematological disorders, homosexual individuals and drug users.
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D001782:Blood Donors; D001938:Brazil; D017977:Deltaretrovirus / Q000276:immunology; D006800:Deltaretrovirus Infections / Q000150:complications / Q000453:epidemiology* / Q000276:immunology; D005260:Female; D006678:HIV / Q000276:immunology; D015483:HIV Antibodies; D006679:HIV Seropositivity / Q000453:epidemiology* / Q000276:immunology; D006801:Humans; D007199:Indians, South American; D008232:Lymphoproliferative Disorders / Q000150:complications; D008297:Male; D008875:Middle Aged
chemical_list: D000914:Antibodies, Viral; D015483:HIV Antibodies