[The value of NMR spectroscopy in the study of myocardial ischemia and in cardiovascular pharmacology].
Nuclear magnetic resonance spectroscopy is a non-destructive method used to investigate the intracellular repercussions of experimental myocardial ischaemia. The effectiveness of drugs or cardioplegic agents in preserving myocardial metabolism during and immediately after ischaemia can be tested on various models. The results obtained in different experiments and the metabolic studies conducted in patients treated with cardiotropic drugs illustrate the value of this method in cardiovascular pharmacology.
D000319:Adrenergic beta-Antagonists / Q000493:pharmacokinetics* / Q000627:therapeutic use; D003327:Coronary Disease / Q000188:drug therapy / Q000378:metabolism*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D010758:Phosphorus / Q000378:metabolism; D010759:Phosphorus Isotopes
D000319:Adrenergic beta-Antagonists; D010759:Phosphorus Isotopes; D010758:Phosphorus
Intérêts de la spectroscopie RMN dans l'étude de l'ischémie myocardique et en pharmacologie cardiovasculaire.