Neuroleptic malignant syndrome: a review of the Wellington experience.
The neuroleptic malignant syndrome is a potentially lethal complication of central dopamine antagonism. We report five cases, occurring in the Wellington region in the last 4 years. Three of the cases are reported in detail and the diagnostic difficulties and therapeutic strategies are reviewed. Particular attention is drawn to the use of the depot intramuscular phenothiazine formulations which were clearly implicated in our experience.
D000328:Adult; D000368:Aged; D014150:Antipsychotic Agents / Q000009:adverse effects; D003692:Delayed-Action Preparations; D006801:Humans; D008297:Male; D008875:Middle Aged; D009459:Neuroleptic Malignant Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D009520:New Zealand; D010640:Phenothiazines
D014150:Antipsychotic Agents; D003692:Delayed-Action Preparations; D010640:Phenothiazines