title: Phospholipase D activity of Vibrio damsela cytolysin and its interaction with sheep erythrocytes.
abstract: Exposure of sheep erythrocytes to sublytic amounts of Vibrio damsela cytolysin markedly reduced their membrane sphingomyelin content and their sensitivity to lysis by the sphingomyelin-dependent cytolysins staphylococcal sphingomyelinase C (beta-toxin) and helianthin. The toxin was found to be a phospholipase D active against sphingomyelin.
mesh_terms: D000818:Animals; D003064:Cnidarian Venoms / Q000378:metabolism; D003603:Cytotoxins / Q000378:metabolism*; D004910:Erythrocyte Membrane / Q000378:metabolism*; D006461:Hemolysis; D010739:Phospholipase D / Q000378:metabolism*; D010740:Phospholipases / Q000378:metabolism*; D013109:Sphingomyelins / Q000378:metabolism; D013210:Staphylococcus / Q000201:enzymology; D014733:Vibrio / Q000201:enzymology*
chemical_list: D003064:Cnidarian Venoms; D003603:Cytotoxins; D013109:Sphingomyelins; C038137:cytolysin III (Stoichactis helianthus); D010740:Phospholipases; D010739:Phospholipase D