title: Effects of synthetic biologically active peptides on giant neurones identified in the left buccal ganglion of an African giant snail (Achatina fulica Férussac).
abstract: 1. The effects of synthetic biologically active peptides, including Met-enkephalin, substance P, oxytocin, Arg-vasopressin, proctolin and FMRFamide, on the following four buccal neurones were examined: d-LBAN (dorsal-left buccal anterior neurone), d-LBMN (dorsal-left buccal medial neurone), d-LBCN (dorsal-left buccal central neurone) and d-LBPN (dorsal-left buccal posterior neurone). These peptides were examined at 10(-4) M. 2. Oxytocin excited d-LBAN and slightly excited d-LBCN, while this inhibited d-LBMN. Arg-vasopressin excited slightly d-LBAN and d-LBCN, but this had some times no effect. FMRFamide inhibited d-LBAN, and slightly inhibited d-LBCN. 3. No direct synaptic connection from the two ventral cerebral giant neurones, v-LCDN and v-RCDN, to the four buccal giant neurones was found, though the two cerebral neurones innervate the cerebro-buccal connectives.
mesh_terms: D000818:Animals; D001127:Arginine Vasopressin / Q000494:pharmacology; D002610:Cheek; D019835:FMRFamide; D005724:Ganglia / Q000187:drug effects*; D006728:Hormones / Q000494:pharmacology; D066298:In Vitro Techniques; D008564:Membrane Potentials / Q000187:drug effects; D009474:Neurons / Q000187:drug effects*; D009479:Neuropeptides / Q000494:pharmacology; D009842:Oligopeptides / Q000494:pharmacology; D010121:Oxytocin / Q000494:pharmacology; D010455:Peptides / Q000494:pharmacology*; D012908:Snails; D013570:Synaptic Membranes / Q000187:drug effects
chemical_list: D006728:Hormones; D009479:Neuropeptides; D009842:Oligopeptides; D010455:Peptides; D001127:Arginine Vasopressin; D010121:Oxytocin; C011536:proctolin; D019835:FMRFamide