title: Ultrastructural demonstration of the catecholaminergic innervation of vasopressin neurons in the paraventricular nucleus of the rat by double-labeling immunocytochemistry.
abstract: The catecholaminergic innervation of vasopressin (VP) neurons in the paraventricular nucleus (PVN) of the rat was studied at the electron microscopic level by double-labeling immunocytochemistry combining the preembedding peroxidase-antiperoxidase method with the postembedding immunogold staining method. Tyrosine hydroxylase-like immunoreactive nerve terminals were found to establish synapses with neurophysin II-like immunoreactive neuronal perikarya and their processes. This provides morphological evidence for catecholaminergic control of the release of VP, at the PVN level.
mesh_terms: D000818:Animals; D002395:Catecholamines / Q000032:analysis*; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D009481:Neurophysins / Q000032:analysis*; D010286:Paraventricular Hypothalamic Nucleus / Q000032:analysis* / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains; D014446:Tyrosine 3-Monooxygenase / Q000032:analysis; D014667:Vasopressins / Q000032:analysis*
chemical_list: D002395:Catecholamines; D009481:Neurophysins; D014667:Vasopressins; D014446:Tyrosine 3-Monooxygenase