title: Leukocyte numbers during the humoral and cell-mediated immune response of Japanese quail after microwave irradiation in ovo.
abstract: 1. Coturnix coturnix japonica eggs were exposed to 2.45-GHz continuous wave microwave radiation at an incident power density of 5 mW/cm2 (SAR = 4 mW/g) during the first 12 days of embryogeny. After hatching, leukocyte differential changes were measured in response to an injection with Alectoris graeca chukar red blood cells (CRBC) and in response to a phytohemagglutinin (PHA) injection in irradiated and nonirradiated (sham) quail of both sexes. 2. Microwave irradiation did not affect anti-CRBC hemagglutinin titers, PHA-evoked dermal swelling or leukocyte numbers and percentages. 3. In both the irradiated and sham irradiated males, lymphocyte percentages decreased while heterophil percentages increased after CRBC or PHA injection. 4. In ovo irradiation with microwaves did not alter the time course of either a humoral immune response or a cell-mediated immune response in Japanese quail.
mesh_terms: D000818:Animals; D000917:Antibody Formation / Q000528:radiation effects*; D003370:Coturnix; D007111:Immunity, Cellular / Q000528:radiation effects*; D007958:Leukocyte Count / Q000528:radiation effects*; D008214:Lymphocytes / Q000166:cytology / Q000187:drug effects / Q000276:immunology; D008872:Microwaves