Neuroleptic-induced tics in two hyperactive children.
Two hyperactive boys who had developed motor and phonic tics during stimulant treatment reacted similarly to low doses of haloperidol and thioridazine. Neuroleptic-induced tics may be a consequence of presynaptic dopamine blockade.
D014150:Antipsychotic Agents / Q000009:adverse effects*; D001289:Attention Deficit Disorder with Hyperactivity / Q000188:drug therapy*; D002648:Child; D003913:Dextroamphetamine / Q000009:adverse effects; D006220:Haloperidol / Q000009:adverse effects; D006801:Humans; D008297:Male; D008774:Methylphenidate / Q000009:adverse effects; D011954:Receptors, Dopamine / Q000187:drug effects / Q000502:physiology; D013881:Thioridazine / Q000009:adverse effects; D013981:Tic Disorders / Q000139:chemically induced* / Q000503:physiopathology
D014150:Antipsychotic Agents; D011954:Receptors, Dopamine; D008774:Methylphenidate; D006220:Haloperidol; D013881:Thioridazine; D003913:Dextroamphetamine