A lymphoproliferative disorder caused by human T-lymphotropic virus type I. Demonstration of a continuum between acute and chronic adult T-cell leukemia/lymphoma.
A 35-year-old black man is described who had a human T-lymphotropic virus type I (HTLV-I) infection while living in a non-endemic region. A lymphoproliferative disorder developed that might be considered as a transition stage between acute and chronic adult T-cell leukemia/lymphoma. This suggests that HTLV-I-induced neoplasias represent a continuous disease spectrum.
D000328:Adult; D001706:Biopsy; D004279:DNA, Viral / Q000302:isolation & purification*; D017977:Deltaretrovirus / Q000235:genetics*; D006800:Deltaretrovirus Infections / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008232:Lymphoproliferative Disorders / Q000209:etiology / Q000473:pathology*; D008297:Male
D004279:DNA, Viral