Urinary excretion of D-glucaric acid in porphyria cutanea tarda.
Twenty patients with porphyria cutanea tarda who had ingested no alcohol for at least 10 days before sampling were found to possess urinary D-glucaric acid levels similar to those of 30 clinically healthy controls. Correlation between urinary excretion of D-glucaric acid on the one hand and plasma or urinary porphyrin concentrations on the other was not statistically significant. These results suggest that the high urinary concentrations of D-glucaric acid found in porphyria cutanea tarda patients by Budillon et al. (Acta Hepato-Gastroenterol. 25 (1978) 267) may have been due to recent consumption of alcohol rather than to the porphyrin pathology.
D000428:Alcohol Drinking; D005937:Glucaric Acid / Q000652:urine*; D006801:Humans; D008297:Male; D011164:Porphyrias / Q000652:urine*; D011166:Porphyrins / Q000097:blood / Q000652:urine; D012871:Skin Diseases / Q000652:urine*; D013400:Sugar Acids / Q000652:urine*; D005723:gamma-Glutamyltransferase / Q000097:blood
D011166:Porphyrins; D013400:Sugar Acids; D005723:gamma-Glutamyltransferase; D005937:Glucaric Acid