Levodopa in restless legs.
The effectiveness of levodopa in the treatment of restless legs was assessed in a double-blind trial. 20 patients were given levodopa and lactose on alternate days. Treatment was continued until patients stated a preference for one of the treatments or were unable to discriminate between the two. 17 patients preferred levodopa, none lactose, and 3 were unable to discriminate. The 17 patients who responded to levodopa reported complete relief.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001545:Benserazide / Q000008:administration & dosage; D002214:Capsules; D002648:Child; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007785:Lactose / Q000008:administration & dosage; D007980:Levodopa / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012148:Restless Legs Syndrome / Q000188:drug therapy*
D002214:Capsules; D007980:Levodopa; D001545:Benserazide; D007785:Lactose