[Changes in portal hemodynamics during pharmacologic stimulation: somatostatin vs glypressin].
Sixteen patients with cirrhosis of the liver and a history of haemorrhaging oesophageal varices all given Warren-type splenorenal bypasses were subjected to intraoperative measurement of portal flow and pressure after the administration of Somatostatin and Glypressin. Glypressin was distinctly more effective in producing a significant and long term reduction in portal flow and pressure. Somatostatin made no significant difference to these parameters.
D001794:Blood Pressure / Q000187:drug effects*; D006801:Humans; D008103:Liver Cirrhosis / Q000503:physiopathology; D008236:Lypressin / Q000031:analogs & derivatives* / Q000494:pharmacology; D011168:Portal System / Q000187:drug effects*; D012039:Regional Blood Flow / Q000187:drug effects; D013004:Somatostatin / Q000494:pharmacology*; D000077585:Terlipressin; D013997:Time Factors
D008236:Lypressin; D013004:Somatostatin; D000077585:Terlipressin
Variazioni dell'emodinamica portale sotto stimolo farmacologico: Somatostatina vs Glipressina.