DNA polymorphisms, identified by an X-chromosome short-arm probe L 1.28 (DXS7), in different racial groups.
Restriction fragment length polymorphisms of the L1.28 probe which is closely linked to X-linked disorders, retinitis pigmentosa and Norrie disease, were studied in samples from England, India and Nigeria. The frequency of the A2 allele (9-kb fragment) was 0.23, 0.55 and 0.46 in England, India and Nigeria, respectively. The differences between the English and Indian populations were highly significant.
D000483:Alleles; D004247:DNA / Q000032:analysis; D004274:DNA, Recombinant; D004739:England; D005006:Ethnicity; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers; D007194:India; D008297:Male; D009549:Nigeria; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D014960:X Chromosome
D004274:DNA, Recombinant; D005819:Genetic Markers; D004247:DNA