title: Ulcerative colitis in West Indian immigrants.
abstract: Over a 15-year period six patients (five female) of Afro-Caribbean origin presented with ulcerative colitis from a community of this ethnic extraction numbering 47,000 persons. The disease was characterised by an acute severe presentation, extensively affected bowel, an active course of disease and a propensity for severe hypersensitive reactions to oral sulphasalazine. These findings are of particular implication in the management of ulcerative colitis in West Indians.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003093:Colitis, Ulcerative / Q000188:drug therapy / Q000453:epidemiology*; D004342:Drug Hypersensitivity; D004739:England; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012460:Sulfasalazine / Q000009:adverse effects / Q000627:therapeutic use; D014900:West Indies / Q000208:ethnology
chemical_list: D012460:Sulfasalazine