title: Neuroendocrine (carcinoid) tumor of the lung and type I multiple endocrine neoplasia.
abstract: We have described a case of MEN-I in association with a benign pulmonary carcinoid tumor. Two other members of our patient's family also had MEN-I and benign carcinoid or adenomatous lung tumors. Hormonal assays of our patient's carcinoid lesion showed the production of gastrin, gastrin-releasing peptide, neurotensin, and somatostatin, but not serotonin, a hormonal profile distinct from those previously reported in carcinoid lung tumors unassociated with MEN-I.
mesh_terms: D002276:Carcinoid Tumor / Q000235:genetics* / Q000378:metabolism; D005260:Female; D019886:Gastrin-Releasing Peptide; D005755:Gastrins / Q000378:metabolism; D006801:Humans; D008175:Lung Neoplasms / Q000235:genetics* / Q000378:metabolism; D008875:Middle Aged; D009377:Multiple Endocrine Neoplasia / Q000235:genetics*; D009496:Neurotensin / Q000378:metabolism; D010375:Pedigree; D010455:Peptides / Q000378:metabolism; D013004:Somatostatin / Q000378:metabolism
chemical_list: D005755:Gastrins; D010455:Peptides; D009496:Neurotensin; D013004:Somatostatin; D019886:Gastrin-Releasing Peptide