Analysis for linkage between F13A and three chromosome 6 marker loci: evidence for 6pter:F13A:HLA:GLO1:cen gene order.
The results of the present study provide independent support for F13A:HLA linkage and refine the F13A:HLA and F13A:GLO1 linkage relationships. Analysis of the corresponding recombination fractions for the total paternal F13A:HLA and F13A:GLO1 peak lod scores (z) indicates a locus order of 6pter:F13A:HLA:GLO1:cen. Lod scores between F13A and PLG, a locus recently assigned to chromosome 6, exclude close linkage between these loci.
D002648:Child; D002896:Chromosomes, Human, Pair 6; D005176:Factor XIII / Q000235:genetics*; D005260:Female; D005796:Genes; D008040:Genetic Linkage; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D007791:Lactoylglutathione Lyase / Q000235:genetics*; D008190:Lyases / Q000235:genetics*; D008285:Major Histocompatibility Complex; D008297:Male; D011503:Transglutaminases
D006680:HLA Antigens; D005176:Factor XIII; D011503:Transglutaminases; D008190:Lyases; D007791:Lactoylglutathione Lyase