Coexistence of sporadic multiple endocrine neoplasia and scapular ectopic breast. Coincidence or biologically associated?
We describe a patient who presented with sporadic pheochromocytoma and parathyroid adenoma in the absence of medullary thyroid carcinoma, which coexisted with fully developed scapular ectopic breast tissue. If not coincidental, this association might support the concept that all components of multiple endocrine neoplasia type IIA originate from embryonic ectodermal tissue, and that sporadic multiple endocrine neoplasia type IIA, as well as ectopic breast tissue, may result from a noxious event at a critical embryonic stage.
D000236:Adenoma / Q000209:etiology*; D000310:Adrenal Gland Neoplasms / Q000209:etiology*; D001940:Breast; D002828:Choristoma / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009377:Multiple Endocrine Neoplasia / Q000209:etiology*; D010282:Parathyroid Neoplasms / Q000209:etiology*; D010673:Pheochromocytoma / Q000209:etiology*; D012540:Scapula