title: [Chlordesmethyldiazepam as an anesthesia-inducing agent: time of loss of consciousness. Statistical analysis in man].
abstract: .1 mg/kg e.v. of chlordesmethyldiazepam, a 1.4 benzodiazepine derivative, were given in induction of anaesthesia of 60 plastic-reconstructive surgery patients respectively in 30 (Group 1.30 patients) and in 60 sec (Group 2.30 patients) to assess the times to spontaneous closing of the eyes and to disappearance of the palpebral reflex. It is concluded that the reflex times are not significantly different in both groups.
mesh_terms: D000328:Adult; D000368:Aged; D000771:Anesthesia, Intravenous; D000777:Anesthetics; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001569:Benzodiazepines; D003975:Diazepam / Q000031:analogs & derivatives*; D006801:Humans; D008875:Middle Aged; D003708:Nordazepam / Q000031:analogs & derivatives* / Q000494:pharmacology; D011229:Preanesthetic Medication; D013997:Time Factors; D014474:Unconsciousness
chemical_list: D000777:Anesthetics; D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D003708:Nordazepam; C013434:chlordesmethyldiazepam; D003975:Diazepam
vernacular_title: Il clordemetildiazepam come farmaco ipnoinducente: tempo di perdita di coscienza. Analisi statistica nell'uomo.