title: Histological and immunohistochemical study on ontogeny of the endocrine cells in the quail gizzard.
abstract: The pre- and post-hatching development and differentiation of the endocrine cells in quail gizzard were examined histologically and immunohistochemically. A total of 158 heads (from 5th d of incubation to adult) were used in this study. The formation of gizzard tubular glands began from 11th d of incubation. 8 kinds of endocrine cells, argyrophil cells, and gastrin releasing polypeptide (GRP)-, 5-hydroxytryptamine (5-HT)-, somatostatin-, glucagon-, avian pancreatic polypeptide (APP)-, neurotensin-, and gastrin-immunoreactive cells were detected in the gizzard. These endocrine cells began to appear from 10th d of incubation. Argyrophil cells and GRP-immunoreactive cells in the gizzard were increased with age. Other kinds of immunoreactive cells were found rarely and irregularly, and some of them were found transitory in the embryonic stage.
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D003370:Coturnix / Q000033:anatomy & histology*; D004702:Endocrine Glands / Q000166:cytology*; D019886:Gastrin-Releasing Peptide; D005895:Gizzard, Avian / Q000166:cytology*; D005934:Glucagon / Q000378:metabolism; D007124:Immunoenzyme Techniques; D009496:Neurotensin / Q000378:metabolism; D010455:Peptides / Q000378:metabolism; D011784:Quail / Q000033:anatomy & histology*; D012701:Serotonin / Q000378:metabolism; D013004:Somatostatin / Q000378:metabolism
chemical_list: D010455:Peptides; D012701:Serotonin; D009496:Neurotensin; D013004:Somatostatin; D019886:Gastrin-Releasing Peptide; D005934:Glucagon