Polyarteritis nodosa and familial Mediterranean fever.
A 22-year-old familial Mediterranean fever (FMF) patient was hospitalized for continuous fever, myalgia, hypertension, vertigo and a petechial rash. Laboratory findings revealed hyperglobulinaemia, thrombocytosis and a leukaemoid reaction. While on steroid therapy the patient sustained a haemorrhage into a renal aneurysm which responded to gel foam embolization. After 12 months of follow-up his condition remained stable under treatment with cyclophosphamide, prednisone and antihypertensive medications. This case provides the fourth example of polyarteritis nodosa associated with FMF.
D000005:Abdomen / Q000098:blood supply; D000328:Adult; D000783:Aneurysm / Q000209:etiology / Q000628:therapy; D001314:Auscultation; D004621:Embolization, Therapeutic; D010505:Familial Mediterranean Fever / Q000150:complications*; D006801:Humans; D008297:Male; D010488:Polyarteritis Nodosa / Q000150:complications*; D012077:Renal Artery; D012422:Rupture, Spontaneous