title: Epidemic yellow fever in eastern Nigeria, 1986.
abstract: An epidemic of yellow fever occurred in the eastern part of Nigeria during the second half of 1986. Oju, in Benue State, was the most heavily affected region, but yellow fever also occurred in surrounding areas, particularly Ogoja, in Cross River State. In Oju, the mean attack and mortality rates were 4.9% and 2.8%, respectively. Sex and age specific rates were highest in males and in the 20-29 yr age group. The overall case fatality rate was approximately 50%. Diagnosis was confirmed by IgM capture enzyme-linked immunosorbent assay (ELISA) and complement fixation (CF) tests. Entomological investigations implicated Aedes africanus as the epidemic vector. Oju alone probably had about 9800 cases of yellow fever with jaundice, and some 5600 deaths. Outbreaks of this nature could be prevented by inclusion of yellow fever in the Expanded Programme on Immunisation, in areas subject to recurrent epidemics.
mesh_terms: D000293:Adolescent; D000328:Adult; D000330:Aedes / Q000302:isolation & purification; D000367:Age Factors; D000818:Animals; D002648:Child; D004196:Disease Outbreaks; D004199:Disease Vectors / Q000302:isolation & purification; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009549:Nigeria; D012621:Seasons; D012737:Sex Factors; D015004:Yellow Fever / Q000453:epidemiology* / Q000401:mortality / Q000517:prevention & control