Determination of cardiac output and other reference physiology parameters in lightly anesthetized dogs.
1. Cardiac output; arterial, pulmonary artery, central venous and pulmonary wedge pressures; heart rate, hematocrit, and plasma sodium and potassium; arterial and mixed venous blood gases; and respiratory rates were measured in 45 mixed sex, non-pregnant, clinically normal mongrel dogs of 8-30 kilograms body weight following light anesthesia with halothane/50% N20-02. 2. Arithmetic means and standard deviations were calculated to develop tables of reference values. 3. Mean measured cardiac outputs were found to be 31-59% higher in these dogs than the values indicated by published standards; cardiac indices were 30-44% higher; heart rates were 16-30% lower; calculated stroke volumes were 60-112% greater; and total peripheral resistances were 35-57% less than the standard published values. 4. All other measured or calculated parameters fell within previously published canine or human reference limits.
D000768:Anesthesia, General; D000818:Animals; D001794:Blood Pressure; D002302:Cardiac Output; D004285:Dogs / Q000502:physiology*; D005260:Female; D006221:Halothane; D006339:Heart Rate; D006400:Hematocrit; D008297:Male; D010100:Oxygen / Q000097:blood; D010101:Oxygen Consumption; D012016:Reference Values; D012119:Respiration; D012964:Sodium / Q000097:blood; D013318:Stroke Volume; D014655:Vascular Resistance
D012964:Sodium; D010100:Oxygen; D006221:Halothane