title: [Effect of long-term anti-arrhythmia treatment on the status of ischemic heart disease patients].
abstract: Standard ECG recording, prolonged ECG monitoring and bicycle ergometry were used in 329 coronary patients. Ventricular extrasystole of grades 2-5 (Lown's classification) was diagnosed in 126. The patients were randomly allocated to the main and control groups. Prolonged continuous treatment of the main-group patients with propranolol and other anti-arrhythmic drugs resulted in reduced occurrence of arrhythmic episodes, and lower heart rates and arterial blood pressure as well as alleviation of clinical anginal symptoms, as compared to the controls treated in local outpatient clinics.
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000009:adverse effects / Q000627:therapeutic use; D000328:Adult; D000787:Angina Pectoris / Q000150:complications / Q000188:drug therapy; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000453:epidemiology / Q000517:prevention & control; D003327:Coronary Disease / Q000150:complications / Q000188:drug therapy*; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D005082:Physical Exertion; D013997:Time Factors
chemical_list: D000319:Adrenergic beta-Antagonists; D000889:Anti-Arrhythmia Agents
vernacular_title: Vliianie dlitel'nogo antiaritmicheskogo lecheniia na sostoianie bol'nykh ishemicheskoĭ bolezn'iu serdtsa.