Effect of high carbohydrate diet on serum gamma-glutamyl transpeptidase fraction pattern in Japanese young men.
Changes in the activity of serum gamma-glutamyl transpeptidase (gamma-GTP) and the percentage of the gamma-GTP fraction in healthy young men given a high carbohydrate diet (480-636 g/day, 80% of the total energy) for 21 days were examined. Serum total gamma-GTP activity showed no significant change in four healthy young volunteers who received high carbohydrate diet for 21 days. However, the percentage of the gamma-GTP (1) fraction increased significantly (P less than 0.01) from the basal level of 55.6 +/- 4.0% to 67.6 +/- 0.9% on day 10, and then decreased to 58.4 +/- 1.4% on day 21. When the experimental diet was replaced by usual diet, the percentage of the gamma-GTP (1) fraction returned to the same level as before the experiment. It is concluded from the results that the nutrient intake affects the percentage of gamma-GTP (1), but not the total serum gamma-GTP activity.
D000328:Adult; D004040:Dietary Carbohydrates / Q000008:administration & dosage*; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D008297:Male; D009752:Nutritional Status; D005723:gamma-Glutamyltransferase / Q000097:blood*
D004040:Dietary Carbohydrates; D007527:Isoenzymes; D005723:gamma-Glutamyltransferase