Herpes simplex virus antibodies in the cerebrospinal fluid of schizophrenic patients.
Antibodies to herpes simplex virus type 1 (HSV-1) were tested in the cerebrospinal fluid (CSF) of 262 schizophrenic patients by virus neutralization test (VNT) and enzyme-linked immunosorbent assay (ELISA). While VNT in the presence of complement revealed antibodies to HSV-1 in 18.3% of samples, ELISA was positive in 61.2% of cases; both tests were positive in 42 samples (16%).
D000914:Antibodies, Viral / Q000134:cerebrospinal fluid*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D009500:Neutralization Tests; D012559:Schizophrenia / Q000134:cerebrospinal fluid*; D018139:Simplexvirus / Q000276:immunology*
D000914:Antibodies, Viral