Putative neurotransmitters in three experimental filariasis models.
Some putative neurotransmitters in three experimental filariasis models were investigated by a new relevant chromatographic method, sensitive and specific. No catecholaminergic compounds have been detected, but serotonin was found in Dipetalonema vitae. However, further investigations revealed very high levels of gamma amino butyric acid (GABA) in the macro-filariae. These data allow us to foresee new fields in filariasis therapeutics.
D006916:5-Hydroxytryptophan / Q000032:analysis; D000818:Animals; D004153:Dipetalonema / Q000032:analysis*; D004298:Dopamine / Q000032:analysis; D004837:Epinephrine / Q000032:analysis; D005260:Female; D005370:Filarioidea / Q000032:analysis*; D008297:Male; D018377:Neurotransmitter Agents / Q000032:analysis*; D009638:Norepinephrine / Q000032:analysis; D012701:Serotonin / Q000032:analysis; D014364:Tryptophan / Q000032:analysis; D005680:gamma-Aminobutyric Acid / Q000032:analysis
D018377:Neurotransmitter Agents; D012701:Serotonin; D005680:gamma-Aminobutyric Acid; D014364:Tryptophan; D006916:5-Hydroxytryptophan; D004298:Dopamine; D009638:Norepinephrine; D004837:Epinephrine