title: Excessive chemotherapy-related myelotoxicity in children with Down syndrome and acute lymphoblastic leukaemia.
mesh_terms: D000293:Adolescent; D000380:Agranulocytosis / Q000139:chemically induced*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D001853:Bone Marrow / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000150:complications*; D006801:Humans; D007945:Leukemia, Lymphoid / Q000188:drug therapy*; D008727:Methotrexate / Q000009:adverse effects; D009503:Neutropenia / Q000139:chemically induced*
chemical_list: D000970:Antineoplastic Agents; D008727:Methotrexate