title: Responses of trout fry (Salmo gairdneri) and Xenopus laevis tadpoles to cadmium and zinc.
abstract: 1. Toxicity of cadmium chloride and zinc sulphate in solution has been determined for Xenopus tadpoles and rainbow trout fry in recirculated water systems. 2. Both animals show approximately equal tolerance of zinc but Xenopus tadpoles tolerate cadmium at approximately 10 times the lethal concentration for trout fry. 3. In the case of Xenopus tadpoles, pre-treatment with sub-lethal concentrations of cadmium or zinc protects against subsequent exposure to either metal. For trout fry, cadmium gives little protection against later exposure to either cadmium or zinc, while zinc gives moderate protection against either metal. 4. Protection is attributed to metallothionein [MT] synthesis.
mesh_terms: D000818:Animals; D002104:Cadmium / Q000378:metabolism / Q000633:toxicity*; D007814:Larva / Q000187:drug effects / Q000378:metabolism; D007928:Lethal Dose 50; D008668:Metallothionein / Q000378:metabolism; D011485:Protein Binding; D014337:Trout; D014982:Xenopus laevis; D015032:Zinc / Q000378:metabolism / Q000633:toxicity*
chemical_list: D002104:Cadmium; D008668:Metallothionein; D015032:Zinc