title: The use of the chelating agent EDTA in the treatment of acute cadmium toxicity, tissue distribution and some blood parameters in the Egyptian toad Bufo regularis.
abstract: Erythrocyte count, haemoglobin content, haematocrit value, erythrocyte sedimentation rate and cadmium accumulation in some organs and tissues were estimated in toads administered 6.2 mg Cd2+/kg i.m. for 4 days. EDTA therapy caused considerable decrease in all the blood parameters studied. A striking reduction in the cadmium content of all the organs and tissues studied except the kidneys was also observed after simultaneous treatment with EDTA.
mesh_terms: D000818:Animals; D002025:Bufonidae; D002104:Cadmium / Q000378:metabolism / Q000633:toxicity*; D004492:Edetic Acid / Q000627:therapeutic use*; D004912:Erythrocytes / Q000187:drug effects; D005260:Female; D006400:Hematocrit; D006454:Hemoglobins / Q000378:metabolism; D014018:Tissue Distribution
chemical_list: D006454:Hemoglobins; D002104:Cadmium; D004492:Edetic Acid