[Effect of the complex treatment of stable stenocardia on the status of the prostacyclin-thromboxane system].
Raised function of platelets with an increase in their aggregation activity in vitro and an increase in spontaneous intravascular activation as well as imbalance of the prostacyclin-thromboxane system with a shift to the predominance of proaggregation agents were detected in CHD patients after myocardial infarction suffering from stable angina. An inhibiting effect of beta-adrenergic receptor blocking agents and acetylsalicylic acid on the synthesis of thromboxane A2 was observed. No marked effect of dipyridamole on the prostacyclin-thromboxane system was noted.
D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage; D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000097:blood* / Q000188:drug therapy; D001241:Aspirin / Q000008:administration & dosage; D004176:Dipyridamole / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D011464:Epoprostenol / Q000097:blood*; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D009566:Nitrates / Q000008:administration & dosage; D010974:Platelet Aggregation / Q000187:drug effects*; D013931:Thromboxanes / Q000097:blood*
D000319:Adrenergic beta-Antagonists; D009566:Nitrates; D013931:Thromboxanes; D004176:Dipyridamole; D011464:Epoprostenol; D001241:Aspirin
Vliianie kompleksnogo lecheniia stabil'noĭ stenokardii na sostoianie prostatsiklin-tromboksanovoĭ sistemy.