Effect of 24-hour starvation on amino acid pool composition and enzyme activities of rat brown adipose tissue.
The effect of 24-hr starvation on the amino acid pool composition and its concentration ratios with respect to blood and plasma as well as the activities of alanine, aspartate and branched chain amino acid transaminases, glutamate dehydrogenase, glutamine synthetase and adenylate deaminase have been studied in rat brown adipose tissue. Starvation induced a considerable decrease of pool amino acid concentration. Alanine and taurine were the amino acids in which the decrease was more marked. Small changes were observed in the activities of the enzymes studied, with decreases only in glutamate dehydrogenase and adenylate deaminase. These changes agree with a decrease in amino acid utilization in this tissue induced by starvation.
D000659:AMP Deaminase / Q000378:metabolism; D000273:Adipose Tissue / Q000201:enzymology* / Q000378:metabolism; D002001:Adipose Tissue, Brown / Q000201:enzymology* / Q000378:metabolism; D000409:Alanine / Q000097:blood; D000596:Amino Acids / Q000097:blood / Q000378:metabolism*; D000818:Animals; D001224:Aspartic Acid / Q000097:blood; D005969:Glutamate Dehydrogenase / Q000378:metabolism; D005974:Glutamate-Ammonia Ligase / Q000378:metabolism; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013217:Starvation; D000637:Transaminases / Q000378:metabolism*
D000596:Amino Acids; D001224:Aspartic Acid; D005969:Glutamate Dehydrogenase; D000637:Transaminases; C019798:branched-chain-amino-acid transaminase; D000659:AMP Deaminase; D005974:Glutamate-Ammonia Ligase; D000409:Alanine