title: Effect of macular ablation on frequency and latency of motion-induced emesis in the squirrel monkey.
abstract: Three previously motion-emetic sensitive squirrel monkeys were rendered refractory to a standard motion-emetic regimen by a two-stage utriculosacculectomy procedure which preserved the cristae ampullares of semicircular canals. Three non-operated control squirrel monkeys tested on the same motion-emetic regimen time schedule as the operated animals remained motion-emetic sensitive with regard to incidence, frequency, and latency of motion-induced emetic responses. Following a sham surgical procedure (stapedectomy) performed on two of the latter animals and one additional new animal, the emetic incidence decreased from 100% to 89%, but the frequency and latency were not altered significantly.
mesh_terms: D008267:Acoustic Maculae / Q000473:pathology / Q000503:physiopathology*; D000818:Animals; D009041:Motion Sickness / Q000150:complications / Q000503:physiopathology*; D012444:Saccule and Utricle / Q000503:physiopathology*; D012453:Saimiri; D013997:Time Factors; D014839:Vomiting / Q000209:etiology / Q000503:physiopathology*