The c-erb-A gene encodes a thyroid hormone receptor.
The cDNA sequence of human c-erb-A, the cellular counterpart of the viral oncogene v-erb-A, indicates that the protein encoded by the gene is related to the steroid hormone receptors. Binding studies with the protein show it to be a receptor for thyroid hormones.
D000595:Amino Acid Sequence; D001483:Base Sequence; D001667:Binding, Competitive; D002471:Cell Transformation, Neoplastic; D004247:DNA / Q000032:analysis; D005796:Genes; D006801:Humans; D007700:Kinetics; D011518:Proto-Oncogene Proteins / Q000235:genetics* / Q000276:immunology; D011519:Proto-Oncogenes; D011988:Receptors, Thyroid Hormone / Q000235:genetics* / Q000378:metabolism
D011518:Proto-Oncogene Proteins; D011988:Receptors, Thyroid Hormone; D004247:DNA