title: A Taq 1 gamma-globin DNA polymorphism: an African-specific marker.
abstract: The allele frequency of a Taq 1 gamma-globin gene restriction fragment length polymorphism (RFLP) is reported in ten population groups. In four African populations the 3.0 kb RFLP is common (50/132 beta A chromosomes), whereas it is completely absent in six European/Asian populations (0/277 beta A chromosomes). This Taq 1 RFLP is thus a specific African population marker.
mesh_terms: D000349:Africa; D000483:Alleles; D002874:Chromosome Mapping; D004262:DNA Restriction Enzymes; D015252:Deoxyribonucleases, Type II Site-Specific; D005787:Gene Frequency; D005819:Genetic Markers; D005914:Globins / Q000235:genetics*; D006801:Humans; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D005819:Genetic Markers; D005914:Globins; D004262:DNA Restriction Enzymes; D015252:Deoxyribonucleases, Type II Site-Specific; C027046:TCGA-specific type II deoxyribonucleases