title: Toxigenic characteristics of Clostridium perfringens type C in enterotoxemia of domestic animals.
abstract: Eleven Clostridium perfringens type C strains isolated from fatal cases of hemorrhagic enterotoxemia of Canadian calves, a piglet, and a foal were studied for the production of soluble antigens. All the isolates from calves and a foal failed to produce delta toxin, but were capable of producing large amounts of lethal beta toxin. A strain isolated from a piglet produced delta, but very little beta toxin. Other differences were relatively minor. The results indicated that young domestic animals may be susceptible to all subtypes of C. perfringens type C. A simple method of using blood agar plates coated with type A antiserum for demonstration of hemolytic patterns was found advantageous in differentiation of C. perfringens strains.
mesh_terms: D000818:Animals; D000829:Animals, Domestic; D001427:Bacterial Toxins / Q000096:biosynthesis*; D002135:Calcium-Binding Proteins; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology; D003015:Clostridium Infections / Q000662:veterinary*; D003016:Clostridium perfringens / Q000378:metabolism*; D004767:Enterotoxemia / Q000382:microbiology*; D006460:Hemolysin Proteins; D006734:Horse Diseases / Q000382:microbiology; D006736:Horses; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology; D010738:Type C Phospholipases
chemical_list: D001427:Bacterial Toxins; C031884:CPB protein, Clostridium perfringens; D002135:Calcium-Binding Proteins; C029352:Clostridium perfringens delta-toxin; D006460:Hemolysin Proteins; C020452:Clostridium perfringens theta-toxin; D010738:Type C Phospholipases; C040649:alpha toxin, Clostridium perfringens