Time-dependent influence of some sedating agents on basic haematological values in various artio- and perissodactylids.
Basic haematological values in 32 animals of five species were estimated after administration of sedating agents. In all species under investigation, a time-dependent decrease of erythrocyte counts, haematocrit values and haemoglobin content was noted during the first 30 min after sedation, for the following 30 min the lowered values remained essentially without any change in zebras. Derived parameters, mean corpuscular haemoglobin, mean corpuscular Hb concentration and mean corpuscular volume did not change during the period of observation. Only insignificant changes in leukocyte count and in the proportion of lymphocytes and neutrophiles were registered. The shortest possible time between sedation and blood sampling is recommended to minimalize a distortion especially in the red blood picture.
D000818:Animals; D000836:Animals, Zoo / Q000097:blood*; D001188:Artiodactyla / Q000097:blood*; D004338:Drug Combinations / Q000494:pharmacology; D005048:Etorphine / Q000494:pharmacology*; D006993:Hypnotics and Sedatives / Q000494:pharmacology*; D008728:Methotrimeprazine / Q000494:pharmacology*; D009019:Morphinans / Q000494:pharmacology*; D010527:Perissodactyla / Q000097:blood*; D013997:Time Factors
D004338:Drug Combinations; D006993:Hypnotics and Sedatives; D009019:Morphinans; C004820:Immobilon; D005048:Etorphine; D008728:Methotrimeprazine