Proton magnetic resonance spectroscopic determination of bethanechol chloride in tablets.
A simple and reliable proton magnetic resonance spectroscopic method was developed for the assay of bethanechol chloride in tablets. The proposed method entails a minimum of procedural steps and reagents. The recovery of bethanechol chloride from synthetic formulations was 99.9 +/- 0.4% (n = 15), CV = 0.4%. Mean assay values for 25 and 10 mg commercial tablets were 100.5% (n = 8) and 99.7% (n = 7) of declared, respectively. A detailed interpretation of the proton magnetic resonance spectrum is also presented.
D018723:Bethanechol; D001626:Bethanechol Compounds / Q000032:analysis*; D004355:Drug Stability; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D011522:Protons; D013607:Tablets
D001626:Bethanechol Compounds; D007202:Indicators and Reagents; D011522:Protons; D013607:Tablets; D018723:Bethanechol