title: Exocrine pancreatic response to secretin and bethanechol in rabbits under hypothermia.
abstract: The effect of the administration of secretin and bethanechol on exocrine pancreatic secretion was studied in rabbits subjected to temperature changes; these involved a drop from 38 degrees C +/- 1 to 28 degrees C +/- 1 (hypothermia) and a subsequent return to 38 degrees C +/- 1 (normothermia). It was observed that hypothermia does not depress the action of secretin on the secretion of fluid, HCO3- and Cl-. Neither was the action of bethanechol on the enzyme secretion affected by changes in body temperature.
mesh_terms: D000818:Animals; D018723:Bethanechol; D001626:Bethanechol Compounds / Q000494:pharmacology*; D001639:Bicarbonates / Q000378:metabolism; D001831:Body Temperature; D002712:Chlorides / Q000378:metabolism; D006867:Hydrolases / Q000378:metabolism; D010179:Pancreas / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D011817:Rabbits; D012633:Secretin / Q000494:pharmacology*
chemical_list: D001626:Bethanechol Compounds; D001639:Bicarbonates; D002712:Chlorides; D018723:Bethanechol; D012633:Secretin; D006867:Hydrolases