Pain therapy: from theoretical research to clinical application.
After a brief review of the supraspinal and spinal effects of morphine, the reference substance for studies on analgesia, the authors expose a synthesis of the recent literature regarding neurotransmitter involvement in pain perception and transmission. From these data, some future prospects for pain treatment research are identified.
D000700:Analgesics / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D009020:Morphine / Q000494:pharmacology; D018377:Neurotransmitter Agents / Q000502:physiology*; D010146:Pain / Q000188:drug therapy* / Q000503:physiopathology; D011957:Receptors, Opioid / Q000187:drug effects; D009435:Synaptic Transmission
D000700:Analgesics; D018377:Neurotransmitter Agents; D011957:Receptors, Opioid; D009020:Morphine