Postirradiation protection of chromosomes by linoleate.
Physiological concentrations of linoleate reduce the frequency of micronuclei and chromosome aberrations in mouse bone marrow cells in vivo and of micronuclei in human lymphocytes in vitro when administered one hour after exposure of the cells to gamma rays.
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects / Q000528:radiation effects; D001854:Bone Marrow Cells; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000187:drug effects* / Q000528:radiation effects; D005720:Gamma Rays; D005856:Germ-Free Life; D006801:Humans; D019787:Linoleic Acid; D008041:Linoleic Acids / Q000494:pharmacology*; D008214:Lymphocytes / Q000166:cytology / Q000187:drug effects / Q000528:radiation effects; D051379:Mice; D008809:Mice, Inbred C3H; D015162:Micronucleus Tests; D011837:Radiation-Protective Agents / Q000494:pharmacology*
D008041:Linoleic Acids; D011837:Radiation-Protective Agents; D019787:Linoleic Acid