Medullary thyroid carcinoma: localization of a mediastinal metastasis with I-131 MIBG.
An I-131 metaiodobenzylguanidine (MIBG) scan was performed in a patient with a familial history of multiple endocrine neoplasia (MEN) type 2 and recurrent medullary thyroid carcinoma (MTC). The scan revealed a mediastinal metastasis from her MTC and there was also an imaging pattern of bilateral adreno-medullary hyperplasia. Although the literature indicates that I-131-MIBG scanning is not sufficiently sensitive for the detection of MTC, this procedure has proven to be of value in the management of chosen patients with MEN-associated MTC.
D019797:3-Iodobenzylguanidine; D000328:Adult; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D009377:Multiple Endocrine Neoplasia / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D013964:Thyroid Neoplasms
D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D019797:3-Iodobenzylguanidine