title: [Clozapine-induced cholestatic liver lesions. A case study].
abstract: During neuroleptic treatment with clozapine, transitory reversible rise in transaminases is not rare, while severe parenchymal damage with icterus has not previously been reported. Such a case is now described: a 54-year-old woman developed clozapine-induced cholestasis with severe liver damage.
mesh_terms: D014150:Antipsychotic Agents / Q000009:adverse effects*; D001706:Biopsy; D056486:Chemical and Drug Induced Liver Injury / Q000150:complications / Q000209:etiology*; D002779:Cholestasis / Q000139:chemically induced*; D003024:Clozapine / Q000009:adverse effects*; D003984:Dibenzazepines / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008099:Liver / Q000187:drug effects / Q000473:pathology; D008875:Middle Aged
chemical_list: D014150:Antipsychotic Agents; D003984:Dibenzazepines; D003024:Clozapine
vernacular_title: Clozapin-induzierter cholestatischer Leberschaden. Eine Fallstudie.