Treatment of neuroleptic malignant syndrome with dopamine hydrochloride: a case report.
A case of neuroleptic malignant syndrome (NMS) is discussed which occurred in a 72-year-old paranoid psychotic patient while on maintainance neuroleptic therapy with penfluridol. A prompt and sufficient improvement in NMS was observed when dopamine hydrochloride (DAHCl) was administered intravenously. It may be possible to explain the effectiveness of DAHCl on the basis of the dopaminergic hypothesis advanced to explain NMS.
D000368:Aged; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004298:Dopamine / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D009459:Neuroleptic Malignant Syndrome / Q000188:drug therapy*; D010259:Paranoid Disorders / Q000188:drug therapy*
D014150:Antipsychotic Agents; D004298:Dopamine