Noninducibility of cytochrome P-450 in the earthworm Dendrobaena veneta.
Cytochrome P-450 has been measured in the earthworm Dendrobaena veneta (Rosa) in a direct spectrophotometric procedure. The P-450 was found not in the dense microsomal fraction, but in the less dense overlying fraction often referred to as buffy coat. Earthworm P-450 was not induced by 3-methylcholanthrene or phenobarbitol.
D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis*; D004790:Enzyme Induction / Q000187:drug effects; D008748:Methylcholanthrene / Q000494:pharmacology; D009835:Oligochaeta / Q000201:enzymology*; D010634:Phenobarbital / Q000494:pharmacology
D008748:Methylcholanthrene; D003577:Cytochrome P-450 Enzyme System; D010634:Phenobarbital