title: Suicide attempts in hypo-oestrogenic phases of the menstrual cycle.
abstract: The phase of the menstrual cycle in women who had attempted suicide was determined by structured interview. 108 young women were investigated within 24 h of the attempt. Patients were grouped according to menstrual week and whether they used oral contraception (OC) (n = 73) or not (n = 35). In OC non-users suicide attempts were associated with low plasma oestradiol: they tended to happen during the first week of the menstrual cycle (42%) and after the fourth week (12%). Frequency of suicide attempts did not vary significantly during the menstrual cycle in OC users. In OC non-users, low oestradiol production may predispose to depression and attempted suicide.
mesh_terms: D000328:Adult; D003276:Contraceptives, Oral / Q000008:administration & dosage; D004958:Estradiol / Q000097:blood; D004967:Estrogens / Q000097:blood*; D005260:Female; D006801:Humans; D008183:Luteal Phase; D008597:Menstrual Cycle; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood; D013406:Suicide, Attempted; D014888:Wechsler Scales
chemical_list: D003276:Contraceptives, Oral; D004967:Estrogens; D011374:Progesterone; D004958:Estradiol; D011388:Prolactin