title: Evidence for a dissimilarity of chicken oviducts differentiated by diethylstilboestrol and oestradiol-17 beta: a study of progesterone-induced egg-white protein (avidin) synthesis.
abstract: The growth and differentiation of chick oviducts were caused by daily diethylstilboestrol (DES) or oestradiol-17 beta (E2) injections, and the effects of these oestrogens on the progesterone-induced production of a biotin-binding egg-white protein (avidin) were studied. In the DES primed oviducts, but not in the E2 primed ones, both DES and E2 administered with progesterone potentiated avidin production 2 to 3-fold, even after 10-day oestrogen withdrawal. The results suggest that DES and E2 prime the avian reproductive target tissue differently.
mesh_terms: D000818:Animals; D001360:Avidin / Q000096:biosynthesis*; D002645:Chickens; D004054:Diethylstilbestrol / Q000494:pharmacology*; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D007700:Kinetics; D010057:Oviducts / Q000187:drug effects* / Q000378:metabolism; D011374:Progesterone / Q000494:pharmacology*
chemical_list: D001360:Avidin; D011374:Progesterone; D004958:Estradiol; D004054:Diethylstilbestrol