Localization of the coagulation factor XIII A subunit gene (F13A) to chromosome bands 6p24----p25.
Electrophoretic studies of the genetic variation of the A subunit of coagulation factor XIII (F13A) have shown that the A subunits expressed in placenta and in the circulation are the products of the same gene locus. In situ hybridization studies with a cDNA fragment encoding the amino terminal region of the A subunit have localized the gene to bands p24----p25 on chromosome 6. This confirms previous studies that showed linkage between F13A and the major histocompatibility complex.
D002871:Chromosome Banding; D002874:Chromosome Mapping; D002896:Chromosomes, Human, Pair 6; D015342:DNA Probes; D004587:Electrophoresis, Agar Gel; D005176:Factor XIII / Q000235:genetics*; D005260:Female; D005312:Fetal Blood; D005786:Gene Expression Regulation; D006801:Humans; D007621:Karyotyping; D009693:Nucleic Acid Hybridization; D010641:Phenotype; D010920:Placenta; D011247:Pregnancy; D011503:Transglutaminases
D015342:DNA Probes; D005176:Factor XIII; D011503:Transglutaminases