Cholinergic antagonists in a solitary wasp venom.
The venom of the solitary wasp Philanthus triangulum contains a cholinergic antagonist of the nicotinic receptor of the rectus abdominis muscle of the frog, Xenopus laevis. The venom of African P. triangulum contains two different cholinergic factors, a competitive and a non-competitive antagonist. The venom of the European P. triangulum may not contain a competitive antagonist of the nicotinic receptor of X. laevis, but only a very strong non-competitive antagonist. The possible non-synonymity of both groups of P. triangulum is discussed.
D000110:Acetylcholinesterase / Q000378:metabolism; D000818:Animals; D001514:Bee Venoms / Q000032:analysis*; D001667:Binding, Competitive; D004593:Electrophorus; D005260:Female; D007700:Kinetics; D008297:Male; D009132:Muscles / Q000378:metabolism; D010277:Parasympathomimetics / Q000302:isolation & purification* / Q000494:pharmacology; D011978:Receptors, Nicotinic / Q000187:drug effects* / Q000378:metabolism; D014862:Wasp Venoms / Q000032:analysis*; D014863:Wasps; D014981:Xenopus
D001514:Bee Venoms; D010277:Parasympathomimetics; D011978:Receptors, Nicotinic; D014862:Wasp Venoms; D000110:Acetylcholinesterase