title: Neuropeptide Y-like immunoreactive C1 neurons in the rostral ventrolateral medulla of the rabbit project to sympathetic preganglionic neurons in the spinal cord.
abstract: After injection into the thoracic spinal cord of the rabbit, gold particles coupled to concanavalin A were found in the rostral ventrolateral medulla in neurons which contained neuropeptide Y-like immunoreactivity. These cells have previously been shown to belong to the C1 catecholamine (presumably adrenaline)- synthesizing group. Nerve terminals in the intermediolateral column contained both tyrosine hydroxylase and neuropeptide Y-like immunoreactivity. When fast blue was injected into the adrenal gland the retrogradely labeled preganglionic neurons were shown to be surrounded by nerve terminals containing neuropeptide Y-like immunoreactivity. Our results indicate that at least some of these terminals derive from C1 neurons which also synthesize neuropeptide Y.
mesh_terms: D000818:Animals; D002395:Catecholamines / Q000378:metabolism; D004525:Efferent Pathways / Q000033:anatomy & histology / Q000378:metabolism; D005728:Ganglia, Sympathetic / Q000166:cytology*; D008297:Male; D008526:Medulla Oblongata / Q000166:cytology* / Q000201:enzymology / Q000378:metabolism; D009412:Nerve Fibers / Q000378:metabolism; D009478:Neuropeptide Y / Q000378:metabolism*; D011817:Rabbits; D013116:Spinal Cord / Q000166:cytology*; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism
chemical_list: D002395:Catecholamines; D009478:Neuropeptide Y; D014446:Tyrosine 3-Monooxygenase