title: The effectiveness of mosquito coils containing esbiothrin under laboratory and field conditions.
abstract: Tests were made to correlate the chemical content of mosquito coils with the knockdown and bite-inhibitory action of the smoke in the laboratory and with the protective effect in field use. Smoke from a blank coil, containing no pyrethroid, gave no knockdown, 10% inhibition of biting in the laboratory using Aedes aegypti, and 39% protection in field tests in village huts on the Kenyan coast with a mixed population of mosquitoes including 71% Anopheles gambiae. Coils containing low experimental contents of 0.044% and 0.099% Esbiothrin, an isomer blend rich in the D-allethrolone ester of D-trans-chrysanthemic acid, gave rapid knockdown in both small chamber and 25 m3 room tests, and 71% and 94% inhibition of biting respectively in the laboratory. In the field they gave 74% and 84% protection from mosquitoes alighting. Chemical content was therefore a good guide to knockdown and bite inhibition in the laboratory and also to the considerable protection found in the field.
mesh_terms: D000330:Aedes / Q000469:parasitology; D000487:Allethrins / Q000031:analogs & derivatives* / Q000494:pharmacology; D000818:Animals; D000852:Anopheles / Q000469:parasitology; D009033:Culicidae / Q000187:drug effects*; D005260:Female; D007299:Insect Bites and Stings / Q000517:prevention & control*; D007306:Insecticides / Q000494:pharmacology; D008297:Male; D009032:Mosquito Control / Q000379:methods*
chemical_list: D000487:Allethrins; D007306:Insecticides; C054159:esbiothrin