Taxol-induced microtubules from different sources: an ultrastructural comparison.
Microtubules from different sources have been isolated using 20 microM taxol. An ultrastructural comparison allowed us to reveal some differences among taxol dependent structures. In tobacco pollen tubes a characteristic system of thin filaments was associated with taxol-induced microtubules. Similar filamentous complexes were not observed in taxol-induced microtubules isolated from other sources.
D000470:Alkaloids / Q000494:pharmacology*; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000648:ultrastructure; D002460:Cell Line; D005347:Fibroblasts / Q000187:drug effects / Q000648:ultrastructure; D006801:Humans; D008870:Microtubules / Q000187:drug effects / Q000648:ultrastructure*; D017239:Paclitaxel; D010947:Plants, Toxic; D013552:Swine; D014026:Nicotiana / Q000648:ultrastructure; D003313:Zea mays / Q000648:ultrastructure
D000470:Alkaloids; D017239:Paclitaxel