title: A double-blind, randomised, placebo-controlled trial of fish oil in psoriasis.
abstract: 28 patients with stable chronic psoriasis completed a trial in which they were randomly allocated to receive either 10 fish-oil capsules ('MaxEPA') or 10 placebo capsules (olive oil) daily. Patients were specifically instructed not to change their normal diet. After 8 weeks' treatment there was a significant lessening of itching, erythema, and scaling in the active treatment group, with a trend towards an overall decrease in body surface area affected. No change occurred in the placebo group.
mesh_terms: D000284:Administration, Oral; D000328:Adult; D004281:Docosahexaenoic Acids; D004311:Double-Blind Method; D004338:Drug Combinations; D004341:Drug Evaluation; D015118:Eicosapentaenoic Acid; D005231:Fatty Acids, Unsaturated / Q000627:therapeutic use*; D005260:Female; D005395:Fish Oils / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011565:Psoriasis / Q000188:drug therapy*; D011897:Random Allocation
chemical_list: D004338:Drug Combinations; D005231:Fatty Acids, Unsaturated; D005395:Fish Oils; C045153:Maxepa; D004281:Docosahexaenoic Acids; D015118:Eicosapentaenoic Acid