[Autoregulation of the cerebral blood flow in normo- and hypertensive rats under beta-adrenoreceptor blockade].
A disorder in the autoregulation of cerebral blood flow due to a drop of arterial blood pressure (shift to the right) occurred earlier in hypotensive rats than in normotensive ones. A beta-adrenergic blockade (obsidan) improved the autoregulation (shift to the left) in both normo- and hypertensive animals.
D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D005260:Female; D006706:Homeostasis / Q000187:drug effects*; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D011412:Propanolamines / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D014655:Vascular Resistance / Q000187:drug effects
D000319:Adrenergic beta-Antagonists; D011412:Propanolamines; C011550:talinolol; D011433:Propranolol
Autoreguliatsiia mozgovogo krovotoka u normo- i gipertenzivnykh krys v usloviiakh blokady beta-adrenoretseptorov.