title: An evaluation system for ranking chemicals with teratogenic potential.
abstract: An evaluation system has been developed which permits comparison of the relative toxicity of chemicals based on their potential to alter embryonal and early-stage fetal development. It was considered necessary, from a regulatory standpoint, to develop a system for ranking chemicals which possess teratogenic potential. A detailed discussion of the various parameters selected and their relative importance is provided.
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000209:etiology; D000818:Animals; D005314:Embryonic and Fetal Development / Q000187:drug effects; D005260:Female; D011247:Pregnancy; D013045:Species Specificity; D013723:Teratogens / Q000145:classification* / Q000494:pharmacology / Q000633:toxicity
chemical_list: D013723:Teratogens