title: [Valpromide (Depamide) in the treatment of acute psychotic states. Open clinical study].
abstract: In an open clinical study on the effect of Depamide in acute psychosis, 59 schizophrenic and 23 manic hospitalized patients were tested. They were divided in two groups: in group A, Depamide was administered only after an initial period of treatment with haloperidol or chlorpromazine; in group B instead, Depamide was added from the beginning of the neuroleptic treatment. The results show that the association of Depamide with neuroleptics leads to a reduction of agitation and of the hospitalization period, whereas it ameliorates the adaptation of the patients to the therapeutic milieu.
mesh_terms: D000208:Acute Disease; D014150:Antipsychotic Agents / Q000008:administration & dosage*; D001714:Bipolar Disorder / Q000188:drug therapy*; D002746:Chlorpromazine / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006220:Haloperidol / Q000008:administration & dosage; D006801:Humans; D008297:Male; D012559:Schizophrenia / Q000188:drug therapy*; D014635:Valproic Acid / Q000008:administration & dosage* / Q000031:analogs & derivatives
chemical_list: D014150:Antipsychotic Agents; D014635:Valproic Acid; D006220:Haloperidol; C004651:dipropylacetamide; D002746:Chlorpromazine
vernacular_title: Le valpromide (Dépamide) dans le traitement d'états psychotiques aigus. Une étude clinique ouverte.