title: A comparison of midazolam and temazepam for premedication of day case patients.
abstract: One hundred patients who underwent day case surgery took part in a randomized double-blind comparison between midazolam 15 mg and temazepam 20 mg orally as premedicants. Postoperative recovery was studied using tests of psychomotor function. Midazolam produced a similar degree of anxiolysis to temazepam and a greater incidence of drowsiness. Recovery was similar after either premedicant and psychomotor function was still depressed 4 hours postoperatively (p less than 0.001). Nearly 90% of patients felt that they had benefitted from either premedicant. We conclude that midazolam is a suitable drug for premedication in day case surgery.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000556:Ambulatory Surgical Procedures; D000762:Anesthesia Recovery Period; D014151:Anti-Anxiety Agents / Q000494:pharmacology; D001007:Anxiety / Q000517:prevention & control; D005425:Flicker Fusion / Q000187:drug effects; D006801:Humans; D008874:Midazolam / Q000494:pharmacology; D008875:Middle Aged; D011229:Preanesthetic Medication; D011597:Psychomotor Performance / Q000187:drug effects; D013693:Temazepam / Q000494:pharmacology; D013997:Time Factors
chemical_list: D014151:Anti-Anxiety Agents; D013693:Temazepam; D008874:Midazolam