title: [Systemic necrotizing vasculitis with bronchial asthma and eosinophilia: Churg-Strauss syndrome].
abstract: Two cases of the Churg-Strauss syndrome are reported, seen within the past year. The first concerned a 31-year-old woman with a rapidly progressive illness characterized by bronchial asthma, leukocytosis and eosinophilia, abdominal pain, diarrhoea and purpura. In the second case, a 47-year-old man had granulomatous epididymitis and interstitial nephritis before the asthma and eosinophilia developed. In both the diagnosis was confirmed by lung biopsy. Immunosuppressive treatment achieved rapid regression of all symptoms and of the eosinophilia, without recurrence so far.
mesh_terms: D000328:Adult; D001249:Asthma / Q000150:complications* / Q000175:diagnosis; D003520:Cyclophosphamide / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010488:Polyarteritis Nodosa / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D013577:Syndrome
chemical_list: D003520:Cyclophosphamide; D011241:Prednisone
vernacular_title: Systemisch nekrotisierende Vaskulitis mit Asthma bronchiale und Eosinophilie. Das Churg-Strauss-Syndrom.