Effects of D-amino acids on growth rate and kidney D-amino acid oxidase in chicks.
Studies were conducted on the effects of feeding D-amino acids on growth rate and D-amino acid oxidase (DAAO) in chick kidney. The crystalline amino acid (AA) diet provided seven amino acids either in the L-form or the DL-form at two concentrations (DL- or .5 DL-AA diets) with all diets containing equal amounts of L-amino acids. Weight gains of chicks fed the DL-AA diet were consistently lower than those fed the L- or .5 DL-AA diet. Kidney DAAO activity was significantly higher in chicks fed either the DL-AA or .5 DL-AA diet as compared with the L-AA diet. Kidney DAAO activity was essentially the same in chicks fed the DL- and .5 DL-AA diets. Increasing the nonspecific nitrogen in the diet had no effect in alleviating growth depression of the DL-AA.
D000596:Amino Acids / Q000494:pharmacology*; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002645:Chickens / Q000254:growth & development* / Q000378:metabolism; D003605:D-Amino-Acid Oxidase / Q000378:metabolism*; D007668:Kidney / Q000187:drug effects / Q000201:enzymology*
D000596:Amino Acids; D003605:D-Amino-Acid Oxidase