[Identification of a metabolite of floctafenine in urinary calculi].
There are three 4-amino-quinolines used for their analgesic properties: glafenine, antrafenine and floctafenin. Urinary calculi due to glafenine have been described since 1980. Recently two cases of renal calculi containing antrafenic acid have been reported. We discovered a metabolite of floctafenin in a bladder calculus and describe its identification by infrared spectrophotometry and thin-layer chromatography.
D000368:Aged; D002855:Chromatography, Thin Layer; D006801:Humans; D008297:Male; D013055:Spectrophotometry, Infrared; D001744:Urinary Bladder Calculi / Q000032:analysis* / Q000139:chemically induced; D062367:ortho-Aminobenzoates / Q000009:adverse effects / Q000032:analysis / Q000378:metabolism*
D062367:ortho-Aminobenzoates
Identification d'un métabolite de la floctafénine dans un calcul urinaire.