Dengue virus isolation by antibody-dependent enhancement of infectivity in macrophages.
Acute-phase serum samples collected during an outbreak of dengue fever and dengue haemorrhagic fever in Penang, Malaysia, were tested by a method involving antibody-dependent enhancement of infectivity in the mouse macrophage-like cell line, P388D1. 58 of 71 (81.7%) serologically positive cases yielded virus.
D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D003715:Dengue / Q000453:epidemiology / Q000276:immunology*; D003716:Dengue Virus / Q000302:isolation & purification* / Q000472:pathogenicity; D004196:Disease Outbreaks; D006801:Humans; D008264:Macrophages / Q000276:immunology / Q000382:microbiology*; D008296:Malaysia; D008722:Methods; D051379:Mice
D000914:Antibodies, Viral