title: Akathisia: the syndrome of motor restlessness.
abstract: Akathisia is a common but frequently unrecognized complication of antipsychotic medication. Affected individuals report an inner discomfort which they attempt to relieve by increased motor activity. This disorder often causes dramatic changes in behavior which may be misinterpreted as signs that more, rather than less, medication is required. Diphenhydramine therapy is often effective in new-onset akathisia. Anticholinergic agents may also be of value.
mesh_terms: D000328:Adult; D000368:Aged; D017109:Akathisia, Drug-Induced; D014150:Antipsychotic Agents / Q000009:adverse effects*; D004155:Diphenhydramine / Q000627:therapeutic use; D006220:Haloperidol / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D011595:Psychomotor Agitation / Q000188:drug therapy; D013577:Syndrome
chemical_list: D014150:Antipsychotic Agents; D004155:Diphenhydramine; D006220:Haloperidol