Clinical and serological features of human herpesvirus-6 infection in three adults.
3 adult patients with serological evidence of human herpesvirus-6 (HHV-6) infection had mild, afebrile illnesses with nonspecific symptoms. In each case, the characteristic clinical feature was the presence of enlarged, bilateral, non-tender, anterior and posterior cervical nodes early in the illness which persisted for up to 3 months. HHV-6 IgG antibody reciprocal titres of 160 to 2560 were found during acute infection, and decreased to a titre of 10 in 1 patient 3 years later. IgM responses were detected at low reciprocal titres (10) in 2 patients and disappeared after several months.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D006564:Herpesviridae / Q000145:classification / Q000276:immunology; D006566:Herpesviridae Infections; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008206:Lymphatic Diseases / Q000097:blood / Q000209:etiology* / Q000276:immunology; D008297:Male; D009333:Neck; D013997:Time Factors
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M