title: Computer applications in intravenous anaesthetic administration.
abstract: The place of computerization in intravenous anaesthesia delivery: Although total intravenous anaesthesia may have advantages over inhalational anaesthesia in certain circumstances, it has drawbacks from the point of view of feedback control. The ideal agent is not available, although di-isopropylphenol holds promise. There is an undefinable end-point. Inadequate dosage produces the extremely unpleasant phenomenon of intra-operative awareness. Future developments, it seems, should include the development of suitable intravenous agents and transducers of anaesthetic depth, rather than increasingly complicated control systems. It is extremely unlikely that a computer will replace the anaesthetist in the foreseeable future. The anaesthetist is still required for, amongst other things, specifying the desired depth of anaesthesia and varying it during the operation, and for responding to unforeseen crises. It may be hoped that, by liberating the anaesthetist from those tasks which can be automated, more time can be devoted to patient monitoring and other aspects of anaesthetic care, thereby improving patient safety. There is an undoubted place for computerized delivery of anaesthesia in teaching (particularly teaching pharmacokinetic principles) and in research (for standardization of anaesthetic depth).
mesh_terms: D000701:Analgesics, Opioid / Q000008:administration & dosage; D000764:Anesthesia, Closed-Circuit / Q000295:instrumentation; D000771:Anesthesia, Intravenous / Q000295:instrumentation*; D000777:Anesthetics / Q000008:administration & dosage; D003201:Computers; D005246:Feedback; D006801:Humans; D008991:Monitoring, Physiologic / Q000295:instrumentation; D009125:Muscle Relaxants, Central / Q000008:administration & dosage; D010636:Phenols / Q000008:administration & dosage; D015742:Propofol
chemical_list: D000701:Analgesics, Opioid; D000777:Anesthetics; D009125:Muscle Relaxants, Central; D010636:Phenols; D015742:Propofol