The origins and trajectories of somatostatin reticulospinal neurons: a potential neurotransmitter candidate of the dorsal reticulospinal pathway.
Somatostatin (SOMA)-immunoreactive neurons present in the nucleus gigantocellularis and nucleus raphe magnus formed the origins of a descending pathway from the rostral medulla to the spinal cord. This descending pathway was traced through the central medullary tegmentum and dorsolateral funiculus to innervate the dorsal horn. The location, trajectories and presumed inhibitory nature of SOMA in the spinal cord suggest that SOMA maybe a potential neurotransmitter candidate for the classic dorsal reticulospinal pathway.
D000818:Animals; D004525:Efferent Pathways / Q000502:physiology; D006168:Guinea Pigs; D009476:Neurons, Efferent / Q000502:physiology*; D018377:Neurotransmitter Agents / Q000502:physiology*; D011903:Raphe Nuclei / Q000502:physiology; D012154:Reticular Formation / Q000502:physiology*; D013004:Somatostatin / Q000502:physiology*; D013116:Spinal Cord / Q000502:physiology*
D018377:Neurotransmitter Agents; D013004:Somatostatin