The analysis of several nonopiate narcotic analgesics and cocaine in serum using high-performance liquid chromatography.
This paper describes a procedure for the quantitative determination of methadone, meperidine, normeperidine, pentazocine, propoxyphene, norpropoxyphene, and dextromoramide in serum down to levels of 10 micrograms/L and of cocaine down to 25 micrograms/L. The procedure involves a simple extraction technique and high-performance liquid chromatography and is suitable for use in overdose drug screening, forensic toxicology, therapeutic drug monitoring, and pharmacokinetic studies.
D000701:Analgesics, Opioid / Q000097:blood*; D002851:Chromatography, High Pressure Liquid; D003042:Cocaine / Q000097:blood*; D006801:Humans; D007202:Indicators and Reagents; D008691:Methadone / Q000097:blood
D000701:Analgesics, Opioid; D007202:Indicators and Reagents; D003042:Cocaine; D008691:Methadone