title: Characterization of sodium carboxymethylcellulose-gelatin complex coacervation by viscosity, turbidity and coacervate wet weight and volume measurements.
abstract: A sodium carboxymethylcellulose (SCMC) and gelatin coacervation system has been evaluated and characterized and the effects of pH and colloid mixing ratio on the coacervation process investigated. The colloid mixing ratio at which optimum coacervation occurred varied with the coacervation pH. A viscometric investigation of various isohydric SCMC-gelatin mixtures was used to predict optimum conditions for complex coacervation. Optimum coacervation occurred at pH 3.5 at a SCMC-gelatin weight ratio of 3:7 for the SCMC complex coacervation system. Turbidity data confirmed these viscometric results. Coacervate wet weight and volume measurements could not be used to predict optimal coacervation conditions due to changes in the coacervate morphology with mixing ratio. At pH values where coacervation did not occur, the viscosity showed unexpected positive deviations from additive behaviour.
mesh_terms: D002266:Carboxymethylcellulose Sodium / Q000032:analysis*; D005780:Gelatin / Q000032:analysis*; D008747:Methylcellulose / Q000031:analogs & derivatives*; D009391:Nephelometry and Turbidimetry; D014783:Viscosity
chemical_list: D005780:Gelatin; D008747:Methylcellulose; D002266:Carboxymethylcellulose Sodium