Presence of D-aspartate oxidase in rat liver and mouse tissues.
Rat liver D-aspartate oxidase activity, which had been reported to be undetectable, was found to be well detectable in dialyzed liver homogenate. The requirements of the enzyme for activity and its sensitivity to inhibitors were identical with the known properties of the enzyme from other sources. We also demonstrated for the first time the presence of the enzyme activity in mouse tissues and some other rat tissues using dialyzed tissue homogenates.
D000594:Amino Acid Oxidoreductases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D000818:Animals; D001224:Aspartic Acid / Q000378:metabolism; D050804:D-Aspartate Oxidase; D005182:Flavin-Adenine Dinucleotide / Q000494:pharmacology; D005971:Glutamates / Q000378:metabolism; D018698:Glutamic Acid; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D010071:Oxaloacetates / Q000378:metabolism; D010100:Oxygen / Q000494:pharmacology; D011773:Pyruvates / Q000378:metabolism; D019289:Pyruvic Acid; D051381:Rats; D011919:Rats, Inbred Strains; D014018:Tissue Distribution
D005971:Glutamates; D010071:Oxaloacetates; D011773:Pyruvates; D005182:Flavin-Adenine Dinucleotide; D001224:Aspartic Acid; D018698:Glutamic Acid; D019289:Pyruvic Acid; D000594:Amino Acid Oxidoreductases; D050804:D-Aspartate Oxidase; D010100:Oxygen