title: Risk of carcinoma following gastric operations for benign disease. A historical cohort study of 3470 patients.
abstract: The risk of stomach cancer was analysed in a cohort of 3470 patients who had had gastric surgery for benign disease between 1900 and 1969. In 87 patients (2.2%) stomach-stump cancer was diagnosed in the follow-up period 1970-84. By comparison with the total incidence of stomach cancer in the same region during the same time period, the observed versus expected ratio in the post-surgery group was 2.1 (p less than 0.001) and did not differ between men and women. At 5-10 years postoperative the risk of cancer was no different from that in the total population, whereas after 40-45 years it was 7.3-fold higher. The risk was unrelated to primary diagnosis or type of operation.
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D005743:Gastrectomy / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009664:Norway; D011183:Postoperative Complications; D012189:Retrospective Studies; D012306:Risk; D012737:Sex Factors; D013272:Stomach Diseases / Q000601:surgery*; D013274:Stomach Neoplasms / Q000453:epidemiology / Q000209:etiology*; D013997:Time Factors