Adrenergic modulation of pancreatic glucagon and insulin secretion in goats.
Five goats were used to investigate adrenergic influences on the secretion of both glucagon and insulin. The secretion of glucagon was augmented via alpha-adrenergic stimulation. The secretion of insulin was enhanced by stimulation of beta-adrenergic receptors and inhibited by alpha-adrenergic stimulation.
D000818:Animals; D002087:Butyrates / Q000494:pharmacology; D020148:Butyric Acid; D004837:Epinephrine / Q000494:pharmacology*; D005260:Female; D005934:Glucagon / Q000378:metabolism*; D005947:Glucose / Q000494:pharmacology; D006041:Goats; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000187:drug effects / Q000378:metabolism*; D007700:Kinetics; D010646:Phentolamine / Q000494:pharmacology*
D002087:Butyrates; D007328:Insulin; D020148:Butyric Acid; D005934:Glucagon; D005947:Glucose; D004837:Epinephrine; D010646:Phentolamine