title: Catecholamine innervation of LH-RH neurons: a developmental study.
abstract: Catecholamine innervation of luteinizing hormone-releasing hormone (LH-RH) cell subtypes in rats was investigated over development using double label, light microscopic immunocytochemistry. Similar results were observed in both sexes. The number of catecholamine-apposed sLH-RH cells remained constant, while the number of catecholamine-apposed iLH-RH cells increased as a function of age. These results suggest that LH-RH cell subtypes are differentially innervated and support the hypothesis that the development of iLH-RH cells represent newly innervated surfaces which are related to changes in the processing of incoming information relevant to reproductive maturation.
mesh_terms: D000375:Aging; D000818:Animals; D001921:Brain / Q000166:cytology / Q000378:metabolism; D002395:Catecholamines / Q000378:metabolism*; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000378:metabolism*; D008297:Male; D009474:Neurons / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012737:Sex Factors; D012741:Sexual Maturation; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism
chemical_list: D002395:Catecholamines; D007987:Gonadotropin-Releasing Hormone; D014446:Tyrosine 3-Monooxygenase