Ultrasonically mediated solute permeation through polymer barriers.
The effects of ultrasound on the permeation of benzoic acid through polydimethylsiloxane, and hydrocortisone through cellulose was investigated. Ultrasonic irradiation resulted in a 23% increase in the permeability coefficient of hydrocortisone in a cellulose film. A 14% increase in permeability coefficient was observed for benzoic acid in a polydimethylsiloxane film. The effects of ultrasound on stagnant aqueous diffusion layers, membrane-solution interfacial temperature, membrane integrity, and diffusant stability were investigated. These factors were not responsible for the observed increases in permeability.
D001565:Benzoates / Q000032:analysis; D019817:Benzoic Acid; D002482:Cellulose; D004058:Diffusion; D004129:Dimethylpolysiloxanes / Q000032:analysis; D006854:Hydrocortisone / Q000032:analysis; D008567:Membranes, Artificial; D010539:Permeability; D011108:Polymers; D012995:Solubility; D013056:Spectrophotometry, Ultraviolet; D013696:Temperature; D014465:Ultrasonics
D001565:Benzoates; D004129:Dimethylpolysiloxanes; D008567:Membranes, Artificial; D011108:Polymers; D019817:Benzoic Acid; D002482:Cellulose; D006854:Hydrocortisone