Compensatory cell proliferation in the kidney after unilateral nephrectomy in mice.
The compensatory cell proliferation in kidney cortex after unilateral nephrectomy in hair-less mice was evaluated by registration of the mitotic rate, thymidine incorporation into DNA, and labelling indices (LI) over a period of 120 h after surgery. Maximal specific activity of DNA and LI were found at 30-36 h postoperatively and preceded the maximal mitotic rate by 6-12 h. The influence of age, sex and diurnal variations was examined.
D000367:Age Factors; D000818:Animals; D002455:Cell Division; D002940:Circadian Rhythm; D004247:DNA / Q000502:physiology; D004847:Epithelial Cells; D005260:Female; D007672:Kidney Cortex / Q000166:cytology*; D007684:Kidney Tubules / Q000166:cytology*; D007700:Kinetics; D008297:Male; D051379:Mice; D008812:Mice, Hairless; D008938:Mitosis; D009392:Nephrectomy; D012737:Sex Factors
D004247:DNA