title: The classic antihistamines (H1 blockers) in respiratory medicine.
abstract: For almost a quarter of a century, the pharmacology of H1 blockers remained quasi-stagnant, isolated from the rapid evolution of clinical pharmacology. However, exciting new developments concerning the role of histamine in asthma, and special pharmacodynamic features of new H1 blockers, have revived our interest in these drugs.
mesh_terms: D000818:Animals; D001249:Asthma / Q000188:drug therapy; D001980:Bronchi / Q000187:drug effects; D002319:Cardiovascular System / Q000187:drug effects; D006634:Histamine H1 Antagonists / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D007109:Immunity / Q000187:drug effects; D007700:Kinetics; D013329:Structure-Activity Relationship
chemical_list: D006634:Histamine H1 Antagonists