title: RFLPs and linkage relationships of the human laminin B2 gene.
abstract: RFLPs for laminin B2 (LAMB2) are reported. These RFLPs were used to study the linkage relationships of LAMB2 to four other genes on lq: Duffy (FY), renin (REN), decay accelerating factor (DAF), and complement receptor 2 (CR2). Multipoint linkage analysis placed LAMB2 between FY and the cluster including REN, DAF, and CR2. This provides a useful bridging polymorphic marker on lq and establishes significant linkage of LAMB2 to FY (theta = 3.23, z = 3.85) and REN (theta = 0.17, z = 4.88).
authors.affiliation: Department of Pediatrics, University of Iowa, Iowa City 52242.
authors.forename: D
authors.initials: D
authors.lastname: Nishimura
authors.forename: K H
authors.initials: KH
authors.lastname: Buetow
authors.forename: Y
authors.initials: Y
authors.lastname: Yamada
authors.forename: J C
authors.initials: JC
authors.lastname: Murray
mesh_terms: D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D005260:Female; D005796:Genes; D008040:Genetic Linkage; D006801:Humans; D007797:Laminin / Q000235:genetics*; D008297:Male; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D007797:Laminin