Genetic evidence for a chromosomally integrated multiresistance plasmid in Salmonella dublin.
Of 1099 isolates of Salmonella dublin during 1985-86, 11 (1%) were resistant to three or more antibiotics. Strain S4659/85, a multiresistant isolate, lacked autonomous R plasmids but showed incompatibility with incH2 plasmids and donated resistance determinants in matings. Transconjugants acquired incomplete R plasmids which integrated stably into a specific chromosomal site. These data provide an insight into the behaviour of R plasmids in S. dublin.
Woodward
M J
MJ
Department of Bacteriology, MAFF Central Veterinary Laboratory, Surrey.
McLaren
I
I
Wray
C
C
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002876:Chromosomes, Bacterial; D003227:Conjugation, Genetic; D004352:Drug Resistance, Microbial; D004587:Electrophoresis, Agar Gel; D008826:Microbial Sensitivity Tests; D011815:R Factors; D012475:Salmonella / Q000187:drug effects / Q000235:genetics*; D014161:Transduction, Genetic
D000900:Anti-Bacterial Agents