Cardiac gated MR imaging of cerebrospinal fluid flow.
This is a preliminary investigation of the cerebrospinal fluid (CSF) spaces using cardiac gated magnetic resonance imaging. A variation of intensity of the signal from the cerebral aqueduct is demonstrated during the cardiac cycle. The pattern of this variation suggests pulsatile CSF flow. Calculations that have been verified by phantom measurements show that CSF flow rates less than 1 mm/s may be detectable. Magnetic resonance may therefore offer a new method for the demonstration and measurement of CSF flow.
Bergstrand
G
G
Bergström
M
M
Nordell
B
B
Ståhlberg
F
F
Ericsson
A
A
Hemmingsson
A
A
Sperber
G
G
Thuomas
K A
KA
Jung
B
B
D002535:Cerebral Aqueduct / Q000502:physiology; D002555:Cerebrospinal Fluid / Q000502:physiology*; D004562:Electrocardiography / Q000379:methods; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D012212:Rheology; D013346:Subarachnoid Space