Enantiospecificity in allergic contact dermatitis. A review and new results in Frullania-sensitive patients.
Allergic contact dermatitis is essentially enantiospecific: sensitization to one enantiomer generally does not imply elicitation to the mirror-image allergens. Examples from patients allergic to Frullania, and from the literature (usnic acids, 4-methoxydalbergiones, gamma-methyl-alpha-methylene-gamma-butyrolactones, frullanolides) are discussed.
Benezra
C
C
Stampf
J L
JL
Barbier
P
P
Ducombs
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G
D015107:4-Butyrolactone / Q000009:adverse effects / Q000031:analogs & derivatives; D000818:Animals; D001572:Benzofurans / Q000009:adverse effects; D016227:Benzoquinones; D003877:Dermatitis, Contact / Q000209:etiology*; D006168:Guinea Pigs; D006801:Humans; D010944:Plants / Q000276:immunology*; D011809:Quinones / Q000009:adverse effects; D012717:Sesquiterpenes / Q000009:adverse effects*; D012882:Skin Tests; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D001572:Benzofurans; D016227:Benzoquinones; D011809:Quinones; D012717:Sesquiterpenes; C007787:frullanolide; C026198:4-methoxydalbergione; C014096:alpha-methylene gamma-butyrolactone; D015107:4-Butyrolactone