Ischaemic pancolitis: a serious complication of chemotherapy in a previously irradiated patient. Case report.
A 47-year-old man underwent orchidectomy and radiotherapy for seminoma. Six years later he received chemotherapy for oesophageal carcinoma. After the second cycle gangrenous pancolitis developed, necessitating total colectomy. The pancolitis presumably resulted from the earlier irradiation and current chemotherapy. This complication has particularly grave implications in oesophageal malignancy, since colon is often used as oesophageal substitute.
Zilling
T L
TL
Department of Surgery, University of Lund, Sweden.
Ahrén
B
B
D002294:Carcinoma, Squamous Cell / Q000628:therapy*; D002945:Cisplatin / Q000009:adverse effects*; D003092:Colitis / Q000209:etiology* / Q000473:pathology; D003131:Combined Modality Therapy; D004407:Dysgerminoma / Q000628:therapy; D004938:Esophageal Neoplasms / Q000628:therapy*; D005472:Fluorouracil / Q000009:adverse effects*; D005734:Gangrene; D006801:Humans; D008297:Male; D008875:Middle Aged
D002945:Cisplatin; D005472:Fluorouracil