title: Umbilical artery creatine kinase brain-band isozyme as a predictor of neonatal periventricular-intraventricular hemorrhage.
abstract: In low-birth-weight neonates, an elevation in the percentage of creatine kinase brain-band isozyme in the umbilical artery was significantly correlated with future development of neonatal grade III and grade IV periventricular-intraventricular hemorrhage, when compared with levels in those neonates who did not show periventricular-intraventricular hemorrhage or who developed grade I and grade II periventricular-intraventricular hemorrhage (p = 0.025). In these neonates the relative levels in maternal venous, umbilical arterial, and umbilical venous samples indicated that the source of the isozyme was fetal.
authors.affiliation: Department of Obstetrics and Gynecology, Nassau County Medical Center, East Meadow, NY.
authors.forename: A
authors.initials: A
authors.lastname: Bardeguez
authors.forename: N
authors.initials: N
authors.lastname: Tejani
authors.forename: U L
authors.initials: UL
authors.lastname: Verma
authors.forename: S J
authors.initials: SJ
authors.lastname: Kim
mesh_terms: D001034:Apgar Score; D001724:Birth Weight; D001784:Blood Gas Analysis; D002543:Cerebral Hemorrhage / Q000175:diagnosis*; D004796:Clinical Enzyme Tests; D003402:Creatine Kinase / Q000097:blood*; D005260:Female; D005312:Fetal Blood / Q000201:enzymology*; D005865:Gestational Age; D006340:Heart Rate, Fetal; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007527:Isoenzymes; D011237:Predictive Value of Tests; D011247:Pregnancy
chemical_list: D007527:Isoenzymes; D003402:Creatine Kinase