title: Umbilical cord blood serosurvey for human immunodeficiency virus in parturient women in a voluntary hospital in New York City.
abstract: The potential spread of the human immunodeficiency virus (HIV) to childbearing women in areas of high acquired immunodeficiency syndrome (AIDS) endemicity is a major public health concern. As a private institution providing obstetric care to such a population of women, we undertook an anonymous HIV cord blood serosurvey to estimate the number of childbearing women at our institution at risk for perinatal transmission of the virus and to assess the success of our voluntary screening program to identify seropositive women. Between November 1987 and January 1988, cord blood samples from all clinic deliveries were analyzed for the presence of HIV antibody. For each sample obtained, the mother's age and site of prenatal care were known. Overall, 2.7% (six of 224) of the samples tested were seropositive; two of the 34 samples (5.9%) from teenage mothers were seropositive. All positive samples were from women who received prenatal care; none were identified through a voluntary screening program based on patient self-acknowledged risk-behavior assessment. This confirms that risk factor history elicited by personal interview is not a reliable screening tool for initiating HIV antibody counseling and testing. The high seropositive rate in teenagers is disturbing and needs further assessment.
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Science, Mount Sinai Medical Center, New York, New York.
authors.forename: R S
authors.initials: RS
authors.lastname: Sperling
authors.forename: H S
authors.initials: HS
authors.lastname: Sacks
authors.forename: L
authors.initials: L
authors.lastname: Mayer
authors.forename: M
authors.initials: M
authors.lastname: Joyner
authors.forename: R L
authors.initials: RL
authors.lastname: Berkowitz
mesh_terms: D015492:AIDS Serodiagnosis; D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis* / Q000635:transmission; D000293:Adolescent; D000328:Adult; D005260:Female; D005312:Fetal Blood / Q000382:microbiology*; D006679:HIV Seropositivity / Q000453:epidemiology*; D006801:Humans; D009519:New York City; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D012307:Risk Factors