Plasma and liver copper values in horses with equine degenerative myeloencephalopathy.
Equine degenerative myeloencephalopathy (EDM) is a common spinal cord disease in the horse. The etiology of EDM currently is unknown. In other species, there are similarities in the clinical signs and neuropathological changes observed in EDM and in copper deficiency. The objective of this study was to determine if horses affected with EDM had low levels of plasma or liver copper. Plasma copper values were determined in 25 EDM affected horses and 35 normal horses. Liver copper levels were determined on 13 EDM affected horses and 22 normal horses. Plasma and liver copper values were not significantly lower in EDM affected horses than in control horses.
Dill
S G
SG
Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.
Hintz
H F
HF
deLahunta
A
A
Waldron
C H
CH
D000818:Animals; D001927:Brain Diseases / Q000097:blood / Q000209:etiology / Q000378:metabolism / Q000662:veterinary*; D003300:Copper / Q000097:blood / Q000172:deficiency / Q000378:metabolism*; D006734:Horse Diseases / Q000097:blood / Q000209:etiology / Q000378:metabolism*; D006736:Horses; D008099:Liver / Q000378:metabolism*; D013118:Spinal Cord Diseases / Q000097:blood / Q000209:etiology / Q000378:metabolism / Q000662:veterinary*
D003300:Copper