title: [Gene amplification and rearrangement of murine ribosomal RNA in virus-induced Rauscher leukemia].
abstract: Using as a hybridization probe cDNA 35s RNA from the Rauscher leukemia cells, a part of rRNA gene cluster from the gene library of mice C-1 erythroleukemia cells has been cloned. Fragment 6.7 kb recloned into pUC19 rRNA was used as a probe to analyse organization of rRNA genes of mice with RL. The observed amplification and rearrangement in genome DNA of spleen cells are determined by a new type of their rRNA genes rearrangement in the nontranscribed as well as in the transcribed part of rRNA.
authors.forename: D A
authors.initials: DA
authors.lastname: Domninskiĭ
authors.forename: E S
authors.initials: ES
authors.lastname: Pokrovskaia
authors.forename: I A
authors.initials: IA
authors.lastname: Smirnova
authors.forename: Z A
authors.initials: ZA
authors.lastname: Butenko
authors.forename: N I
authors.initials: NI
authors.lastname: Grineva
mesh_terms: D000818:Animals; D003001:Cloning, Molecular / Q000379:methods; D004247:DNA; D015342:DNA Probes; D005784:Gene Amplification; D015321:Gene Rearrangement; D005796:Genes; D004915:Leukemia, Erythroblastic, Acute / Q000235:genetics; D007942:Leukemia, Experimental / Q000235:genetics*; D051379:Mice; D008806:Mice, Inbred AKR; D008807:Mice, Inbred BALB C; D009693:Nucleic Acid Hybridization; D010761:Phosphorus Radioisotopes; D011061:Poly A; D012150:Polymorphism, Restriction Fragment Length; D015347:RNA Probes; D012335:RNA, Ribosomal / Q000235:genetics*; D011925:Rauscher Virus
chemical_list: D015342:DNA Probes; D010761:Phosphorus Radioisotopes; D015347:RNA Probes; D012335:RNA, Ribosomal; D011061:Poly A; D004247:DNA
vernacular_title: Amplifikatsiia i perestroĭka genov ribosomnoĭ RNK myshi pri virusindutsirovannom leĭkoze Raushera.