Population genetics of the globin genes in Polynesians.
Globin gene mapping data enable Polynesians to be divided into three distinct groups: (i) Maoris, Cook Islanders, (ii) Tongans, Samoans, (iii) Niue Islanders. Unusual RFLPs detected by the restriction enzymes Apa I and Bgl II are found in Polynesians. A high frequency of alpha-thalassemia in this population is explained by genetic drift and a founder effect.
Trent
R J
RJ
Molecular Biology Laboratory, University of Sydney, NSW, Australia.
Mickleson
K N
KN
Yakas
J
J
Hertzberg
M
M
D005787:Gene Frequency; D015321:Gene Rearrangement; D005914:Globins / Q000235:genetics*; D006801:Humans; D008403:Mass Screening; D012150:Polymorphism, Restriction Fragment Length; D011114:Polynesia
D005914:Globins