title: Risk of lung, larynx, pharynx and buccal cavity cancers among carbon electrode manufacturing workers.
abstract: Among workers employed in factories producing carbon graphite products the risk of cancer due to exposure to polycyclic aromatic hydrocarbons was estimated. In one cohort (plant A), a cancer incidence study was carried out; the number of cases were not significantly increased for lung cancers [7 cases, standardized incidence ratio (SIR) 79] or for cancers of the upper respiratory and alimentary tract (10 cases, SIR 103). In another cohort (plant B), a mortality study was carried out; neither the mortality from lung cancer [13 deaths, standardized mortality ratio (SMR) 118] nor that from upper respiratory and alimentary tract cancers (10 deaths, SMR 125) was significantly higher than expected. Within each cohort, a case-referent study was carried out. In plant A the odds ratios were high but nonsignificant for lung cancers (odds ratio 3.42) and upper respiratory and alimentary tract cancers (odds ratio 2.19) and they showed a nonsignificant relationship with duration of exposure. In plant B, the odds ratios were low for every cancer site.
authors.affiliation: National Institute for Research and Safety, Vandoeuvre, France.
authors.forename: J J
authors.initials: JJ
authors.lastname: Moulin
authors.forename: P
authors.initials: P
authors.lastname: Wild
authors.forename: J M
authors.initials: JM
authors.lastname: Mur
authors.forename: M
authors.initials: M
authors.lastname: Lafontaine
authors.forename: M
authors.initials: M
authors.lastname: Lefer
authors.forename: M
authors.initials: M
authors.lastname: Mercier-Gallay
authors.forename: P
authors.initials: P
authors.lastname: Villemot
authors.forename: V
authors.initials: V
authors.lastname: Whebi
authors.forename: J P
authors.initials: JP
authors.lastname: Coulon
mesh_terms: D002244:Carbon; D004566:Electrodes; D006801:Humans; D007822:Laryngeal Neoplasms / Q000453:epidemiology*; D008175:Lung Neoplasms / Q000453:epidemiology*; D008297:Male; D009062:Mouth Neoplasms / Q000453:epidemiology*; D009784:Occupational Diseases / Q000453:epidemiology*; D010610:Pharyngeal Neoplasms / Q000453:epidemiology*; D012307:Risk Factors
chemical_list: D002244:Carbon