title: Treatment of vocal cord granuloma.
abstract: Combined surgical and conservative therapy (voice therapy, treatment of infections, allergy, oesophageal reflux, and psychogenic stress) has been used in the treatment of non-specific vocal cord granuloma. Such tumors have a great tendency to recur. The 41 patients with vocal cord granuloma in our study (4 women, 37 men, mean age 56 years) were treated at our hospital during 1980-1986. Nine patients were healed with conservative treatment, 32 were treated by laryngomicrosurgery under general anesthesia and jet-ventilation. The latter group was divided into three treatment groups; 8 of these patients were treated with cryotherapy, 9 with postoperative steroids (Prednisolone 40 mg/day in decreasing doses) and antibiotics, and 15 only with microsurgery. At some phase in their treatment 41% of the patients were able to participate in voice therapy. The most recurrences were found in the group treated with cryotherapy, 2.7 rec./pat.; 1.8 rec./pat. were found in the group that underwent surgery, and 1.7 rec./pat. among the patients treated with steroid-antibiotics. In all three groups, some patients experienced recurrences. In the cryotherapy group, however, recurrent granulomas were large and required reoperation, while those in patients treated with steroid-antibiotics were small and could be cured using conservative therapy. If granuloma does not disturb the voice, cause respiratory obstruction or demand histopathological diagnosis, surgery is contraindicated. Cryotherapy does not help traditional surgery, while steroid-antibiotics administered postoperatively seem to help the healing process.
authors.affiliation: Kuopio University Central Hospital, Department of Otolaryngology and Phoniatrics, Finland.
authors.forename: M
authors.initials: M
authors.lastname: Jaroma
authors.forename: L
authors.initials: L
authors.lastname: Pakarinen
authors.forename: J
authors.initials: J
authors.lastname: Nuutinen
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003452:Cryosurgery; D005260:Female; D006102:Granuloma, Laryngeal / Q000628:therapy*; D006801:Humans; D007818:Laryngeal Diseases / Q000628:therapy*; D008297:Male; D008866:Microsurgery; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D012008:Recurrence; D014827:Vocal Cords / Q000601:surgery; D014834:Voice Training
chemical_list: D000900:Anti-Bacterial Agents; D011239:Prednisolone