title: Polymorphism of the complement C3 gene in the Lebanese population.
abstract: The C3 protein polymorphism was studied in 300 unrelated Lebanese. The gene frequencies were calculated and compared with other populations. DNA samples digested with various endonucleases were hybridized with a C3 probe, which was found to detect a frequent Sac I restriction fragment length polymorphism (RFLP) and a less frequent Taq I RFLP in the Lebanese population, as well as in the French populations.
authors.affiliation: Laboratoire d'Immunogénétique, UA CNRS 1191, Génétique Moléculaire, Université des Sciences et Techniques du Languedoc, Montpellier, France.
authors.forename: N
authors.initials: N
authors.lastname: Ghanem
authors.forename: M P
authors.initials: MP
authors.lastname: Lefranc
authors.forename: G
authors.initials: G
authors.lastname: Lefranc
mesh_terms: D000483:Alleles; D003176:Complement C3 / Q000235:genetics*; D015252:Deoxyribonucleases, Type II Site-Specific; D005787:Gene Frequency; D006801:Humans; D007861:Lebanon; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D003176:Complement C3; C024408:endodeoxyribonuclease SacI; D015252:Deoxyribonucleases, Type II Site-Specific; C027046:TCGA-specific type II deoxyribonucleases