title: Magnetic resonance imaging after closed head injury in children.
abstract: Magnetic resonance imaging (MRI) was performed in a series of 21 children and adolescents who had been hospitalized after sustaining closed head injuries of varying severity at least 6 months previously. Areas of high intensity in the parenchyma were present in 8 of the 11 severely injured patients, whereas MRI findings were normal in all 10 patients with mild-to-moderate head injuries. Lesions involving the subcortical white matter were confined to severely injured patients whose clinical features were compatible with diffuse axonal injury. Neuropsychological assessment disclosed deficits primarily in the severely injured patients; these deficits were significantly associated with persistent lesions visualized by MRI. Serial MRI and neurobehavioral assessment following early injury may be useful in documenting cognitive impairment in relation to structural alterations of the young brain.
authors.affiliation: Division of Neurosurgery, University of Texas Medical Branch, Galveston.
authors.forename: H S
authors.initials: HS
authors.lastname: Levin
authors.forename: E G
authors.initials: EG
authors.lastname: Amparo
authors.forename: H M
authors.initials: HM
authors.lastname: Eisenberg
authors.forename: M E
authors.initials: ME
authors.lastname: Miner
authors.forename: W M
authors.initials: WM
authors.lastname: High
authors.forename: L
authors.initials: L
authors.lastname: Ewing-Cobbs
authors.forename: J M
authors.initials: JM
authors.lastname: Fletcher
authors.forename: F C
authors.initials: FC
authors.lastname: Guinto
mesh_terms: D000293:Adolescent; D001930:Brain Injuries / Q000175:diagnosis*; D002648:Child; D003072:Cognition Disorders / Q000175:diagnosis; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009483:Neuropsychological Tests; D013997:Time Factors; D014057:Tomography, X-Ray Computed