Cortisol levels in human follicular fluid.
This study shows that cortisol levels in follicular fluids in stimulated cycles were correlated with oocyte maturity and in vitro fertilizability. The levels were significantly higher than the concentrations found in spontaneous cycles. Our findings suggest that the presence of cortisol in follicular fluid may play a role in follicular development and oocyte maturation.
Fateh
M
M
Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, School of Medicine, Philadelphia.
Ben-Rafael
Z
Z
Benadiva
C A
CA
Mastroianni
L
L
Flickinger
G L
GL
D000735:Androstenedione / Q000032:analysis; D001826:Body Fluids / Q000032:analysis; D004958:Estradiol / Q000032:analysis; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis* / Q000097:blood; D007247:Infertility, Female / Q000378:metabolism*; D006080:Ovarian Follicle / Q000032:analysis*; D011374:Progesterone / Q000032:analysis; D011863:Radioimmunoassay; D013739:Testosterone / Q000032:analysis
D013739:Testosterone; D000735:Androstenedione; D011374:Progesterone; D004958:Estradiol; D006854:Hydrocortisone