title: [BCG in reflux].
abstract: Nine patients with radiologically proven vesicorenal reflux (3 bilateral, 4 unilateral, 2 with unilateral double-J stents) received intravesical bacillus Calmette-Guérin (BCG) as prophylactic treatment for recurrent superficial bladder carcinoma. One patient with a double-J stent suffered an attack of high fever, probably following obstruction of the stent. All other patients tolerated one cycle or two cycles (5 of 9 patients) of 6 weekly instillations without significant complications. There was no increased toxicity compared with a control group of 39 patients without reflux who were receiving BCG. Topical intravesical immunotherapy with BCG in patients with vesicorenal reflux can be given without a rise in the complication rate; indeed, in view of the multifocal appearance of urothelial carcinoma in this subgroup, this type of therapy even appears to be desirable.
authors.affiliation: Klinik für Urologie, Medizinischen Universität zu Lübeck.
authors.forename: A
authors.initials: A
authors.lastname: Böhle
authors.forename: J
authors.initials: J
authors.lastname: Schüller
authors.forename: A
authors.initials: A
authors.lastname: Knipper
mesh_terms: D000283:Administration, Intravesical; D000368:Aged; D000369:Aged, 80 and over; D001500:BCG Vaccine / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology; D001749:Urinary Bladder Neoplasms / Q000601:surgery / Q000628:therapy*; D014718:Vesico-Ureteral Reflux / Q000150:complications* / Q000209:etiology
chemical_list: D001500:BCG Vaccine
vernacular_title: BCG bei Reflux.