Abdominal aortic aneurysm: consequences of a positive family history.
To assess the prevalence of coexisting abdominal aortic aneurysm (AAA) within certain families, a retrospective review was carried out of patients who had undergone AAA repair over a 5-year period. Contact was made with 305 families (52%) and a positive history of an affected, first-degree relative was obtained in 34 (11%). A known AAA was reported to affect approximately 20% of siblings at risk when the proband had an affected parent or sibling. Siblings of patients with an affected first-degree relative represent a high-risk group that may benefit from a screening program for earlier detection and elective management of AAA.
Cole
C W
CW
Department of Surgery, University of Ottawa, Ont.
Barber
G G
GG
Bouchard
A G
AG
McPhail
N V
NV
Roberge
C
C
Waddell
W G
WG
Wellington
J L
JL
D001012:Aorta, Abdominal / Q000601:surgery; D001014:Aortic Aneurysm / Q000235:genetics* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D012189:Retrospective Studies