title: [The role of radiotherapy in the treatment of supraglottic laryngeal tumors. Case reports].
abstract: Radiotherapy obtains better results when employed alone, in initial forms (T1-T2), and after surgery, when loco-regional relapse incidence reduces. Personal results in the treatment of laryngeal cancer are reported in 281 patients. One-hundred-forty-seven patients treated with exclusive radiotherapy had 5-year global and NED survival of 32.7% and 26.6%; 5-year NED survival in particular was 78.7% for T1-T2 and 22.9% for T3-T4. Subsequently 52.8% of patients relapsed. One-hundred-thirty-four patients treated with postoperative radiotherapy had a 5-year global and NED survival of 58.8% and 52.1%; relapses were observed in 20.9% of patients, mostly in cases with histological G3 grading or with rupture of the lymph node capsule. The importance of exclusive and postoperative radiotherapy with reference to prognostic factors that are deduced from the histological specimen is underlined.
authors.affiliation: Ospedale Maggiore, Novara.
authors.forename: M
authors.initials: M
authors.lastname: Krengli
authors.forename: G
authors.initials: G
authors.lastname: Gambaro
authors.forename: P
authors.initials: P
authors.lastname: Pisani
authors.forename: G
authors.initials: G
authors.lastname: Pastore
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005069:Evaluation Studies as Topic; D005260:Female; D005931:Glottis; D006801:Humans; D007822:Laryngeal Neoplasms / Q000150:complications / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D007825:Laryngectomy; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011182:Postoperative Care
vernacular_title: Ruolo della radioterapia nel trattamento dei tumori laringei sovraglottici. Contributo casistico.