title: Metabolic profiling of urinary organic acids by single and multicolumn capillary gas chromatography.
abstract: High-resolution gas chromatography (HRGC) and gas chromatography/mass spectrometry (GC/MS) are the techniques of choice to determine the retention indices of more than 200 organic acids as their trimethylsilyl (TMS) or oxime-trimethylsilyl derivatives. Several types of apolar and semipolar fused-silica capillary columns (OV-1, SE-52, and OV-1701), used to analyze and separate organic acids isolated from urine samples, are evaluated.
authors.affiliation: Laboratoria voor Medische Biochemie en voor Klinische Analyse, Gent, Belgium.
authors.forename: M F
authors.initials: MF
authors.lastname: Lefevere
authors.forename: B J
authors.initials: BJ
authors.lastname: Verhaeghe
authors.forename: D H
authors.initials: DH
authors.lastname: Declerck
authors.forename: J F
authors.initials: JF
authors.lastname: Van Bocxlaer
authors.forename: A P
authors.initials: AP
authors.lastname: De Leenheer
authors.forename: R M
authors.initials: RM
authors.lastname: De Sagher
mesh_terms: D000143:Acids / Q000652:urine*; D000328:Adult; D002675:Child, Preschool; D002849:Chromatography, Gas; D005410:Flame Ionization; D006801:Humans; D007223:Infant
chemical_list: D000143:Acids