title: Gastrointestinal disconnection and the treatment of intra-abdominal sepsis.
abstract: Current operative treatment for intra-abdominal sepsis secondary to internal gastrointestinal fistulas is aimed at wide drainage of septic foci and elimination of continued peritoneal soilage. Although methods for surgical drainage of abscesses and fistulous tracts are well established, the optimal method for surgical prevention of continued peritoneal soilage remains controversial. The authors applied the principle of complete gastrointestinal disconnection and performed diversion of the gastrointestinal tract and tube decompression proximal to the fistulous opening in the treatment of 22 critically ill patients with intra-abdominal sepsis from gastric or small bowel fistulas. Patient survival varied according to the level of the site of gastrointestinal leakage. All patients (5 out of 5) who had leakage in the distal small bowel survived. Six of nine (66%) patients with leakage from the proximal jejunum and six of eight (75%) of patients with gastroduodenal leakage survived. The overall survival rate of 77 per cent observed in this group of patients supports the authors' hypothesis that complete gastrointestinal disconnection is a valuable adjunct in the treatment of these severely ill patients.
authors.affiliation: Department of Surgery, University of Kentucky Chandler Medical Center, Lexington.
authors.forename: R W
authors.initials: RW
authors.lastname: Schwartz
authors.forename: D E
authors.initials: DE
authors.lastname: Barker
authors.forename: W O
authors.initials: WO
authors.lastname: Griffen
authors.forename: C B
authors.initials: CB
authors.lastname: Ross
authors.forename: W E
authors.initials: WE
authors.lastname: Strodel
mesh_terms: D000005:Abdomen; D001424:Bacterial Infections / Q000209:etiology / Q000601:surgery* / Q000628:therapy; D013505:Digestive System Surgical Procedures; D004386:Duodenum / Q000601:surgery; D005747:Gastric Fistula / Q000150:complications; D006801:Humans; D007412:Intestinal Fistula / Q000150:complications; D007583:Jejunum / Q000601:surgery; D008297:Male; D008722:Methods; D008875:Middle Aged; D013270:Stomach / Q000601:surgery