Gamma glutamyl transferase in diabetic rats. The effect of insulin treatment.
In rats, streptozotocin-induced diabetes resulted in the increase of plasma gamma GT. A daily dose of 2 U protamine zinc insulin for two weeks did not affect the high levels of both gamma GT and glucose. Supplementation with 3 U insulin for only one week reduced both gamma GT and glucose levels. This indicates that insulin treatment could correct the rise of the enzyme level found in some diabetic patients.
Shoukry
M I
MI
Department of Biochemistry, Faculty of Medicine, Kuwait University, Safat.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy / Q000201:enzymology*; D049528:Insulin, Long-Acting / Q000627:therapeutic use*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values; D005723:gamma-Glutamyltransferase / Q000097:blood*
D001786:Blood Glucose; D049528:Insulin, Long-Acting; D005723:gamma-Glutamyltransferase