title: Criteria for the oral glucose tolerance test in pregnant and non-pregnant Nigerian women.
abstract: In order to establish diagnostic criteria for detection of abnormal oral glucose tolerance test (OGTT) in pregnant and non-pregnant Nigerian women, the test was performed in 25 non-pregnant and 60 pregnant non-diabetic women at various trimesters of pregnancy. The upper limit of normal plasma glucose was the same as that from caucasian populations with respect to the fasting values but much less at 60 and 120 min. When compared to the non-pregnant controls, fasting plasma glucose was significantly lower during pregnancy, however, there was no change in glucose tolerance during pregnancy. The possible reasons for these observations are discussed and it would appear that our criteria would be the ideal ones to use for clinical purposes in Nigerian women.
authors.affiliation: Department of Obstetrics and Gynaecology, Faculty of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria.
authors.forename: F E
authors.initials: FE
authors.lastname: Okonofua
authors.forename: F A
authors.initials: FA
authors.lastname: Amole
authors.forename: S O
authors.initials: SO
authors.lastname: Ayangade
authors.forename: T
authors.initials: T
authors.lastname: Nimalaraj
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000175:diagnosis*; D005215:Fasting; D005260:Female; D005951:Glucose Tolerance Test / Q000592:standards*; D006801:Humans; D007408:Intestinal Absorption; D009549:Nigeria; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000175:diagnosis*; D011446:Prospective Studies; D013997:Time Factors
chemical_list: D001786:Blood Glucose