title: Acute myocardial infarction due to coronary spasm associated with L-thyroxine therapy.
abstract: A 63-year-old man with hypothyroidism is described. He had been receiving L-thyroxine therapy following mitral valve surgery. About three weeks into the therapy regimen, he complained of severe retrosternal chest oppression. Electrocardiographic findings and laboratory data indicated a diagnosis of acute myocardial infarction due to the L-thyroxine therapy. Emergency selective coronary angiography was performed. Comparing his coronary angiograms with those obtained before surgery indicated a severely spastic left coronary artery. We believe this is the first report of myocardial infarction due to coronary spasm, demonstrated by angiography associated with L-thyroxine therapy.
authors.affiliation: Department of Cardiology, Komatsushima Red Cross Hospital, Tokushima, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Hiasa
authors.forename: T
authors.initials: T
authors.lastname: Ishida
authors.forename: T
authors.initials: T
authors.lastname: Aihara
authors.forename: M
authors.initials: M
authors.lastname: Bando
authors.forename: Y
authors.initials: Y
authors.lastname: Nakai
authors.forename: Y
authors.initials: Y
authors.lastname: Kataoka
authors.forename: H
authors.initials: H
authors.lastname: Mori
mesh_terms: D000792:Angiography; D017023:Coronary Angiography; D003329:Coronary Vasospasm / Q000139:chemically induced*; D004562:Electrocardiography; D006801:Humans; D007037:Hypothyroidism / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000139:chemically induced*; D013974:Thyroxine / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D013974:Thyroxine