title: Surgical treatment of tumors in the anterior skull base using the transbasal approach.
abstract: Five patients with tumors in the anterior skull base were surgically treated using the transbasal approach, which permits removal of the tumor, repair of the dura mater, and reconstruction of the skull base in a one-stage procedure. By using autologous materials for the bone graft and pedunculated pericranial flap for the reconstruction, the intracranial structures are separated from the air-filled nasal and paranasal cavities. No postoperative complications such as wound infection and leakage of cerebrospinal fluid were encountered. The use of this surgical technique makes it possible to extirpate brain tumors that heretofore have been considered unresectable.
authors.affiliation: Department of Neurosurgery, Osaka University Medical School, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Arita
authors.forename: S
authors.initials: S
authors.lastname: Mori
authors.forename: M
authors.initials: M
authors.lastname: Sano
authors.forename: T
authors.initials: T
authors.lastname: Hayakawa
authors.forename: K
authors.initials: K
authors.lastname: Nakao
authors.forename: N
authors.initials: N
authors.lastname: Kanai
authors.forename: H
authors.initials: H
authors.lastname: Mogami
mesh_terms: D000236:Adenoma / Q000601:surgery*; D000328:Adult; D003399:Craniotomy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000601:surgery*; D008579:Meningioma / Q000601:surgery*; D008875:Middle Aged; D009298:Nasal Polyps / Q000601:surgery; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D009447:Neuroblastoma / Q000601:surgery; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000601:surgery; D009669:Nose Neoplasms / Q000601:surgery; D010255:Paranasal Sinus Neoplasms / Q000601:surgery*; D010911:Pituitary Neoplasms / Q000601:surgery*; D012888:Skull Neoplasms / Q000601:surgery