title: Abnormal cardiovascular reflexes in patients with gastro-oesophageal reflux.
abstract: Using five non-invasive tests, abnormalities of cardiovascular reflex function were found in 20 of 50 patients with gastro-oesophageal reflux. Abnormalities of pupil cycle time, an index of non-vagal parasympathetic function, were found in only a few patients, implying that the cardiovascular abnormalities observed were not part of a generalised parasympathetic defect. The findings are consistent with the hypothesis that an abnormality of vagal function may contribute to the pathogenesis of gastro-oesophageal reflux.
authors.affiliation: University Department of Medicine, Royal Infirmary, Edinburgh.
authors.forename: T K
authors.initials: TK
authors.lastname: Chakraborty
authors.forename: A L
authors.initials: AL
authors.lastname: Ogilvie
authors.forename: R C
authors.initials: RC
authors.lastname: Heading
authors.forename: D J
authors.initials: DJ
authors.lastname: Ewing
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001341:Autonomic Nervous System / Q000503:physiopathology; D002319:Cardiovascular System / Q000503:physiopathology*; D005260:Female; D005764:Gastroesophageal Reflux / Q000503:physiopathology*; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D011680:Pupil / Q000502:physiology; D012021:Reflex, Abnormal / Q000503:physiopathology*