title: Plasmid-determined inducible efflux is responsible for resistance to cadmium, zinc, and cobalt in Alcaligenes eutrophus.
abstract: In Alcaligenes eutrophus CH34, resistance to chromate is plasmid determined, inducible, and based on decreased net accumulation of the metal anion. Plasmid-encoded resistances to zinc, cadmium, cobalt, and nickel are resulting from inducible, energy-dependent cation efflux systems.
authors.affiliation: Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago 60680.
authors.forename: D H
authors.initials: DH
authors.lastname: Nies
authors.forename: S
authors.initials: S
authors.lastname: Silver
mesh_terms: D000421:Alcaligenes / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D002104:Cadmium / Q000378:metabolism / Q000494:pharmacology*; D002840:Chromates / Q000494:pharmacology; D003035:Cobalt / Q000378:metabolism / Q000494:pharmacology*; D004352:Drug Resistance, Microbial / Q000235:genetics; D007700:Kinetics; D009532:Nickel / Q000378:metabolism; D011815:R Factors; D015032:Zinc / Q000378:metabolism / Q000494:pharmacology*
chemical_list: D002840:Chromates; D002104:Cadmium; D003035:Cobalt; D009532:Nickel; D015032:Zinc