title: A report of two long-surviving cases of pulmonary lymphangioleiomyomatosis and the response to progesterone therapy.
abstract: Two cases of pulmonary lymphangioleiomyomatosis, with survival between 12 and 28 years are described. Both were treated with medroxyprogesterone acetate with a slight initial improvement in both lung function and exercise tolerance, and no further deterioration during the period of follow-up of 10-20 months. The results are discussed and other reports of hormonal treatment of this rare condition are reviewed.
authors.forename: E H
authors.initials: EH
authors.lastname: Sawicka
authors.forename: A J
authors.initials: AJ
authors.lastname: Morris
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008168:Lung / Q000503:physiopathology; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000503:physiopathology; D008203:Lymphangiomyoma / Q000188:drug therapy* / Q000503:physiopathology; D008232:Lymphoproliferative Disorders / Q000188:drug therapy*; D008525:Medroxyprogesterone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D017258:Medroxyprogesterone Acetate; D012129:Respiratory Function Tests
chemical_list: D017258:Medroxyprogesterone Acetate; D008525:Medroxyprogesterone