Citrobacter freundii produces an 18-amino-acid heat-stable enterotoxin identical to the 18-amino-acid Escherichia coli heat-stable enterotoxin (ST Ia).
We purified and sequenced the heat-stable enterotoxin produced by Citrobacter freundii. The toxin was detected during purification by reaction with monoclonal antibody to Escherichia coli heat-stable enterotoxin. The C. freundii toxin amino acid sequence was identical to that of the 18-amino-acid heat-stable enterotoxin (STa) produced by toxigenic E. coli.
Guarino
A
A
Department of Internal Medicine, University of Cincinnati College of Medicine, Ohio 45267.
Giannella
R
R
Thompson
M R
MR
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000302:isolation & purification*; D001427:Bacterial Toxins / Q000096:biosynthesis* / Q000302:isolation & purification; D002954:Citrobacter / Q000032:analysis / Q000378:metabolism*; D004768:Enterotoxins / Q000096:biosynthesis* / Q000302:isolation & purification; D029968:Escherichia coli Proteins; D008969:Molecular Sequence Data; D012689:Sequence Homology, Nucleic Acid
D000596:Amino Acids; D001427:Bacterial Toxins; D004768:Enterotoxins; D029968:Escherichia coli Proteins; C034151:heat stable toxin (E coli)