title: Rectal diazepam in pediatric status epilepticus.
abstract: Status epilepticus is a neurologic emergency with an 8% to 12% mortality. Rapid ablation of seizure activity is imperative. Although intravenous administration of diazepam is the preferred immediate treatment, vascular access is often difficult to achieve. Rectal administration of diazepam is easily accomplished during status epilepticus. Five cases in which diazepam administered in the rectal lumen stopped seizure activity are reported. Rectal diazepam appears to be safe and efficacious. It should be considered as an alternate to intravenous therapy when immediate vascular access is delayed. Rectal diazepam may have great benefit in the prehospital setting.
authors.affiliation: Emergency Medicine Residency, Michigan State University, Lansing.
authors.forename: A
authors.initials: A
authors.lastname: Albano
authors.forename: E J
authors.initials: EJ
authors.lastname: Reisdorff
authors.forename: J G
authors.initials: JG
authors.lastname: Wiegenstein
mesh_terms: D000285:Administration, Rectal; D002648:Child; D003975:Diazepam / Q000008:administration & dosage* / Q000627:therapeutic use; D004630:Emergencies; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D013226:Status Epilepticus / Q000188:drug therapy*
chemical_list: D003975:Diazepam