title: Cytogenetic analysis of ten human seminomas.
abstract: A cytogenetic analysis of ten seminomas has been carried out after direct harvesting of the tumor cells. Modal chromosome numbers ranged from 63 to 112. These numbers were in agreement with flow cytometric determination of the DNA content of the tumors. Eight tumors had at least one copy of an i(12p) among other chromosomal abnormalities. Two seminomas lacked the i(12p).
authors.affiliation: Department of Human Genetics, State University of Groningen, The Netherlands.
authors.forename: S M
authors.initials: SM
authors.lastname: Castedo
authors.forename: B
authors.initials: B
authors.lastname: de Jong
authors.forename: J W
authors.initials: JW
authors.lastname: Oosterhuis
authors.forename: R
authors.initials: R
authors.lastname: Seruca
authors.forename: G J
authors.initials: GJ
authors.lastname: te Meerman
authors.forename: A
authors.initials: A
authors.lastname: Dam
authors.forename: H
authors.initials: H
authors.lastname: Schraffordt Koops
mesh_terms: D000328:Adult; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D004273:DNA, Neoplasm / Q000032:analysis; D004407:Dysgerminoma / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D013736:Testicular Neoplasms / Q000235:genetics*
chemical_list: D004273:DNA, Neoplasm