title: Orientation of alpha-helical peptides in a lipid bilayer.
abstract: Samples of pure lipid (dipalmitoylphosphatidylcholine) and lipid containing short alpha-helical peptides were oriented and examined by X-ray diffraction, together with unoriented samples of pure peptide. X-ray reflections from the bilayer and the alpha-helices showed that the peptides had oriented in the bilayer with their helical axes perpendicular to the surface.
authors.affiliation: Physics Department, University of Guelph, Canada.
authors.forename: J C
authors.initials: JC
authors.lastname: Huschilt
authors.forename: B M
authors.initials: BM
authors.lastname: Millman
authors.forename: J H
authors.initials: JH
authors.lastname: Davis
mesh_terms: D015060:1,2-Dipalmitoylphosphatidylcholine; D006860:Hydrogen Bonding; D066298:In Vitro Techniques; D008051:Lipid Bilayers; D008565:Membrane Proteins / Q000648:ultrastructure*; D009842:Oligopeptides / Q000138:chemical synthesis; D014961:X-Ray Diffraction
chemical_list: D008051:Lipid Bilayers; D008565:Membrane Proteins; D009842:Oligopeptides; D015060:1,2-Dipalmitoylphosphatidylcholine