Testicular tumors occurring in non-twin brothers: a case report.
The present report describes two cases of seminoma that occurred simultaneously in non-twin brothers. These siblings were typed for HLA-A, -B, -C and -DR specificities, and manifested identical haplotypes. Sixty-four sets of affected siblings have been reported prior to the present cases. We examined HLA-DR antigen in brothers with testicular tumors and hereditary roles in the etiology are discussed.
Natsume
O
O
Department of Urology, Nara Medical University.
Ozono
S
S
Tsumatani
K
K
Yoshikawa
M
M
Sasaki
K
K
Hirao
Y
Y
Okajima
E
E
D000328:Adult; D004407:Dysgerminoma / Q000235:genetics*; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D008297:Male; D013736:Testicular Neoplasms / Q000235:genetics*
D006680:HLA Antigens