Fibrous papule: a tumor of fibrohistiocytic cells that contain factor XIIIa.
Factor XIIIa, a blood coagulation factor, has been found in a variety of cell types, including dendritic reticulum cells and fibroblast-like mesenchymal cells. We hypothesized that fibrous papule, a lesion of uncertain histogenesis, was composed of dermal stellate cells and in this report demonstrate that this neoplasm consists of cells that contain this factor. Nevus cells do not contain factor XIIIa.
Nemeth
A J
AJ
Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, FL.
Penneys
N S
NS
Bernstein
H B
HB
D001706:Biopsy; D002921:Cicatrix / Q000378:metabolism / Q000473:pathology; D005176:Factor XIII / Q000032:analysis*; D006801:Humans; D007124:Immunoenzyme Techniques; D009506:Nevus / Q000032:analysis / Q000473:pathology; D012878:Skin Neoplasms / Q000032:analysis / Q000473:pathology*; D011503:Transglutaminases
D005176:Factor XIII; D011503:Transglutaminases