Multiple brown tumors in a patient with nutritional secondary hyperparathyroidism.
For years, brown tumors have been considered to be a characteristic of primary hyperparathyroidism. However, since 1963 several reports indicate the incidence of brown tumors in patients with renal secondary hyperparathyroidism to be 1.5%-1.7%. The appearance of multiple brown tumor lesions is rather uncommon in secondary hyperparathyroidism which is also true for malabsorption as its cause. We report on a 56-year-old man presenting with pain in the bones and multiple osteolyses. A bone biopsy specimen and the laboratory examinations were indicative of secondary hyperparathyroidism caused by malabsorption most likely due to Billroth's II/I gastric resection. Thus, the patient's osteolyses represent brown tumors which have been induced by nutritional secondary hyperparathyroidism.
Mergenthaler
H G
HG
Gesellschaft für Strahlen- und Umweltforschung, Institut für Experimentelle Hämatologie, München.
Fink
M
M
Sauer
H
H
Bartl
R
R
Wilmanns
W
W
D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D004377:Dumping Syndrome / Q000150:complications; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000150:complications*; D008286:Malabsorption Syndromes / Q000150:complications; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D011859:Radiography