title: Family screening in medullary thyroid carcinoma presenting without a family history.
abstract: Systematic screening of the families of a series of 39 patients with apparently sporadic medullary thyroid carcinoma detected seven new cases in four families. A negative family history in a patient presenting with medullary thyroid carcinoma is not reliable in excluding familial disease, and family screening should be considered for new patients with medullary thyroid carcinoma.
authors.affiliation: Royal Marsden Hospital, Sutton, Surrey.
authors.forename: B A
authors.initials: BA
authors.lastname: Ponder
authors.forename: N
authors.initials: N
authors.lastname: Finer
authors.forename: R
authors.initials: R
authors.lastname: Coffey
authors.forename: C L
authors.initials: CL
authors.lastname: Harmer
authors.forename: M
authors.initials: M
authors.lastname: Maisey
authors.forename: M G
authors.initials: MG
authors.lastname: Ormerod
authors.forename: M E
authors.initials: ME
authors.lastname: Pembrey
authors.forename: M A
authors.initials: MA
authors.lastname: Ponder
authors.forename: P
authors.initials: P
authors.lastname: Rosswick
authors.forename: S
authors.initials: S
authors.lastname: Shalet
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000175:diagnosis / Q000235:genetics*; D002648:Child; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009377:Multiple Endocrine Neoplasia / Q000175:diagnosis* / Q000235:genetics; D010375:Pedigree; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000235:genetics*