title: Corynebacterium pseudotuberculosis: biochemical properties, production of toxin and virulence of ovine and caprine strains.
abstract: Twenty-two strains of Corynebacterium pseudotuberculosis, the causative agent of caseous lymphadenitis, were isolated from typical abscesses in sheep and goats from flocks in 6 different regions of France and were characterized. These strains were uniform in biochemical characteristics, susceptibility to 8 antimicrobial agents, and virulence for OF1 mice. All these strains produced an exotoxin, identified by inhibition of staphylococcal beta-hemolysin. Moreover, this study showed that strain 19R, a streptomycin-resistant mutant used in experimental infection in sheep, possessed the same characteristics as the field strains of C. pseudotuberculosis, except for its resistance to streptomycin (500 micrograms/ml).
authors.affiliation: Institut National de la Recherche Agronomique, Station de Pathologie de la Reproduction, Nouzilly, Monnaie, France.
authors.forename: M
authors.initials: M
authors.lastname: Pépin
authors.forename: A
authors.initials: A
authors.lastname: Boisramé
authors.forename: J
authors.initials: J
authors.lastname: Marly
mesh_terms: D000818:Animals; D001427:Bacterial Toxins / Q000096:biosynthesis*; D003352:Corynebacterium / Q000302:isolation & purification / Q000378:metabolism / Q000472:pathogenicity / Q000502:physiology*; D006041:Goats / Q000382:microbiology*; D012756:Sheep / Q000382:microbiology; D014774:Virulence
chemical_list: D001427:Bacterial Toxins