[The effect of the opioid peptide dalargin on the regeneration of the rat sciatic nerve].
The effect of synthetic analog of leucine enkephalin hexapeptide dalargin on regeneration of peripheral nerves involved an activation of the sensory and motor fibers regeneration after transection and microsurgical restoration of the rat sciatic nerve. Endogenous opioid peptides seem to take part in the regulation of structural homeostasis of the nervous system.
Akoev
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Il'inskiì
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Kolosova
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Titov
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Trofimova
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D000818:Animals; D004743:Enkephalin, Leucine / Q000031:analogs & derivatives* / Q000494:pharmacology; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives*; D008297:Male; D009416:Nerve Regeneration / Q000187:drug effects*; D051381:Rats; D012584:Sciatic Nerve / Q000187:drug effects* / Q000502:physiology
D004743:Enkephalin, Leucine; D016308:Enkephalin, Leucine-2-Alanine; C040996:enkephalin-Leu, Ala(2)-Arg(6)-
Vliianie opiodnogo peptida dalargina na regeneratsiiu sedalishchnogo nerva krysy.