[Clinical experiences with tetrachlorodecaoxide in the local treatment of difficult-to-heal wounds].
Local treatment of difficult wounds with TCDO, a chemically stable, water-soluble compound containing oxygen in a chlorite matrix, is supposed to increase the pO2 in hypoxic wound tissue and to amplify physiological responses of phagocytes in wounds. 21 patients were assigned to two groups, treated by TCDO impregnated dressings twice a day or by TCDO combined with temporary skin coverage Epigard. Daily records of the state of the wounds with regard to exudation, wound cleansing, formation of granulation tissue and epithelisation demonstrated the therapeutic effect of TCDO in the treatment of complicated wounds when primary surgical debridement was sufficient.
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Berufsgenossenschaftliche Unfallklinik Tübingen.
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D000293:Adolescent; D000328:Adult; D000368:Aged; D002713:Chlorine / Q000008:administration & dosage*; D003131:Combined Modality Therapy; D003646:Debridement; D005121:Extremities; D005260:Female; D005465:Fluorocarbon Polymers; D006801:Humans; D008297:Male; D008875:Middle Aged; D010087:Oxides / Q000008:administration & dosage*; D014945:Wound Healing / Q000187:drug effects*; D014946:Wound Infection / Q000188:drug therapy*
D005465:Fluorocarbon Polymers; D010087:Oxides; D002713:Chlorine; C010946:polytetrafluoroethane; C041955:tetrachlorodecaoxide
Klinische Erfahrungen mit TCDO bei der Lokalbehandlung schlecht heilender Wunden.