[The possible participation of protein SH groups and aldehydes in radiation damage of cell membranes].
The sedimentation method was used to study the effect of N-ethylmaleimide, diethyl maleate, formaldehyde, Ca2+, and dithiothreitol on cell membranes. Sedimentation quality of erythrocytes was shown to be modified by the agents that bound protein SH-groups and aggregated proteins.
Proskuriakov
S Ia
SIa
Fileva
T I
TI
Mikhaĭlov
V F
VF
Poverennyĭ
A M
AM
D000447:Aldehydes; D000818:Animals; D001799:Blood Sedimentation; D002118:Calcium / Q000494:pharmacology; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000528:radiation effects*; D005033:Ethylmaleimide / Q000494:pharmacology; D005557:Formaldehyde / Q000494:pharmacology; D066298:In Vitro Techniques; D008298:Maleates / Q000494:pharmacology; D008954:Models, Biological; D051381:Rats; D013438:Sulfhydryl Compounds
D000447:Aldehydes; D008298:Maleates; D013438:Sulfhydryl Compounds; D005557:Formaldehyde; C014476:diethyl maleate; D005033:Ethylmaleimide; D002118:Calcium
O vozmozhnom uchastii belkovykh SH-grupp i al'degidov v radiatsionnom povrezhdenii kletochnykh membran.