Highly selective mu opioid antagonist peptides block spinal mu opioid inhibition of gastrointestinal transit.
Ayres
E A
EA
Department of Pharmacology, University of Arizona, Tucson 85724.
Villar
R
R
Kramer
T H
TH
Kazmierski
W
W
Hruby
V J
VJ
Burks
T F
TF
D000818:Animals; D005772:Gastrointestinal Transit / Q000187:drug effects*; D051379:Mice; D009270:Naloxone / Q000494:pharmacology; D011957:Receptors, Opioid / Q000187:drug effects / Q000502:physiology*; D017450:Receptors, Opioid, mu; D012016:Reference Values; D013004:Somatostatin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D011957:Receptors, Opioid; D017450:Receptors, Opioid, mu; D009270:Naloxone; D013004:Somatostatin