title: Cigarette smoking and exposure to passive smoke are risk factors for cervical cancer.
abstract: Personal cigarette smoking and exposure to passive smoke as risk factors for cervical cancer were examined in a population-based, case-control study conducted in Utah. Personal cigarette smoking was found to increase the risk of cervical cancer, after adjusting for age, educational level, church attendance, and sexual activity. The adjusted risk estimate associated with being a current smoker was 3.42 (95% confidence interval [Cl], 2.10 to 5.57); for having smoked for 5 or more pack-years, it was 2.81 (95% Cl, 1.73 to 4.55); and for having smoked at least 100 lifetime cigarettes, it was 2.21 (95% Cl, 1.44 to 3.39). The adjusted risk estimate (also adjusted for actual cigarettes smoked) associated with passive smoke exposure for 3 or more hours per day was 2.96 (95% Cl, 1.25 to 7.03). Risk from passive smoking was greater in women who were not smokers (odds ratio, 3.43; 95% Cl, 1.23 to 9.54) than in women who smoked (odds ratio, 2.59; 95% Cl, 0.23 to 29.24).
authors.affiliation: Department of Family and Preventive Medicine, University of Utah School of Medicine, Salt Lake City 84132.
authors.forename: M L
authors.initials: ML
authors.lastname: Slattery
authors.forename: L M
authors.initials: LM
authors.lastname: Robison
authors.forename: K L
authors.initials: KL
authors.lastname: Schuman
authors.forename: T K
authors.initials: TK
authors.lastname: French
authors.forename: T M
authors.initials: TM
authors.lastname: Abbott
authors.forename: J C
authors.initials: JC
authors.lastname: Overall
authors.forename: J W
authors.initials: JW
authors.lastname: Gardner
mesh_terms: D000328:Adult; D002278:Carcinoma in Situ / Q000209:etiology; D002294:Carcinoma, Squamous Cell / Q000209:etiology; D003367:Cotinine / Q000097:blood; D003625:Data Collection / Q000379:methods; D004522:Educational Status; D005260:Female; D006801:Humans; D007182:Income; D008875:Middle Aged; D012067:Religion; D012307:Risk Factors; D012747:Sexual Partners; D012907:Smoking / Q000009:adverse effects*; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*; D014589:Utah; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000209:etiology*
chemical_list: D014028:Tobacco Smoke Pollution; D003367:Cotinine