title: Prospective study of a standardized questionnaire to improve clinical estimate of pulmonary embolism.
abstract: A standardized questionnaire was administered to 100 patients suspected of having pulmonary embolism to investigate whether clinical data may be reliably used in the decision-making process of such patients. Questionnaire data were compared with lung scintigraphy outcome and 16 variables were selected as significantly associated with the scintigraphic diagnosis. Based on these variables, patients with abnormal scintigraphy compatible with pulmonary embolism and patients with scintigraphy not compatible with embolism were classified in accordance with the scintigraphic diagnosis. When these 16 variables were tested in an additional validation group, clinical and scintigraphic diagnosis matched in most cases. These results show that clinical data can be used to predict the outcome of lung perfusion scintigraphy in patients suspected of pulmonary embolism. Use of a standardized questionnaire can improve the accuracy of pretest assessment of such patients and positively influence the decisions to start heparin coverage or obtain pulmonary angiography.
authors.affiliation: Second Medical Clinic, University of Pisa, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Celi
authors.forename: A
authors.initials: A
authors.lastname: Palla
authors.forename: S
authors.initials: S
authors.lastname: Petruzzelli
authors.forename: L
authors.initials: L
authors.lastname: Carrozzi
authors.forename: A
authors.initials: A
authors.lastname: Jacobson
authors.forename: G
authors.initials: G
authors.lastname: Cella
authors.forename: C
authors.initials: C
authors.lastname: Giuntini
authors.forename: A A
authors.initials: AA
authors.lastname: Sasahara
mesh_terms: D004562:Electrocardiography; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011655:Pulmonary Embolism / Q000175:diagnosis* / Q000000981:diagnostic imaging; D011859:Radiography; D011877:Radionuclide Imaging; D011795:Surveys and Questionnaires