title: Aortic regurgitation: a common complication after surgery for hypertrophic obstructive cardiomyopathy.
abstract: Surgical ventriculomyectomy and ventriculomyotomy by the aortic approach are safe and effective methods of relieving symptoms and obstruction to left ventricular outflow in patients with hypertrophic obstructive cardiomyopathy. With the addition of Doppler ultrasound to the routine follow-up assessment of these patients an unexpectedly high occurrence of aortic regurgitation was found in the postoperative patients. Because aortic regurgitation has been reported to rarely accompany this condition, 67 patients with hypertrophic obstructive cardiomyopathy were studied clinically and with Doppler echocardiography for the presence and severity of aortic regurgitation. Severity of the regurgitation was quantitated by pulsed or color Doppler echocardiography according to the length and width of the regurgitant jet in at least two views. In 37 patients with hypertrophic obstructive cardiomyopathy who did not undergo surgery, aortic regurgitation was detected in only 1 (3%) by Doppler ultrasound and in none clinically. In 52 patients who did undergo surgery and were studied a mean of 7.8 years postoperatively, aortic regurgitation of trivial to moderate degree was common, being detected in 28 (54%) by Doppler ultrasound and in 6 (12%) clinically. In a subgroup of 22 patients who were studied preoperatively and again early postoperatively (mean 6 weeks), new aortic regurgitation was found in 8 (36%) and was graded as trivial in all. Aortic regurgitation is a common complication related to ventriculomyectomy and ventriculomyotomy in patients with hypertrophic obstructive cardiomyopathy. Although initially trivial, the regurgitation may progress in severity over time. The regurgitation has been well tolerated in all patients studied to date.
authors.affiliation: Division of Cardiology, Toronto General Hospital, Ontario, Canada.
authors.forename: Z
authors.initials: Z
authors.lastname: Sasson
authors.forename: T
authors.initials: T
authors.lastname: Prieur
authors.forename: Y
authors.initials: Y
authors.lastname: Skrobik
authors.forename: J C
authors.initials: JC
authors.lastname: Fulop
authors.forename: W G
authors.initials: WG
authors.lastname: Williams
authors.forename: M A
authors.initials: MA
authors.lastname: Henderson
authors.forename: C
authors.initials: C
authors.lastname: Gresser
authors.forename: E D
authors.initials: ED
authors.lastname: Wigle
authors.forename: H
authors.initials: H
authors.lastname: Rakowski
mesh_terms: D001021:Aortic Valve / Q000473:pathology; D001022:Aortic Valve Insufficiency / Q000175:diagnosis / Q000209:etiology*; D006348:Cardiac Surgical Procedures / Q000379:methods; D002312:Cardiomyopathy, Hypertrophic / Q000473:pathology / Q000601:surgery*; D004452:Echocardiography; D006352:Heart Ventricles; D006801:Humans; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology; D011183:Postoperative Complications; D011184:Postoperative Period