title: Thromboembolic risk factors in patients undergoing maxillofacial surgery for malignancies.
abstract: Venous thromboembolism is a common complication in patients undergoing major surgery. We studied blood coagulation profiles in 16 patients undergoing extensive maxillofacial surgery for oral malignant diseases. Activity of coagulation factor V and levels of antithrombin III were significantly reduced on the first postoperative day. Fibrinogen level showed a continuous increase throughout the observation period. However, no thromboembolic events were observed. It can be concluded that despite a severe alteration of the blood clotting system, maxillofacial surgery does not seem to be associated with postoperative thromboembolism.
authors.affiliation: Department of Oral and Maxillofacial Surgery, University of Vienna, Austria.
authors.forename: I
authors.initials: I
authors.lastname: Watzke
authors.forename: H
authors.initials: H
authors.lastname: Watzke
mesh_terms: D001779:Blood Coagulation Factors / Q000032:analysis; D001780:Blood Coagulation Tests; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D005260:Female; D006258:Head and Neck Neoplasms / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection / Q000009:adverse effects*; D011446:Prospective Studies; D013923:Thromboembolism / Q000209:etiology*
chemical_list: D001779:Blood Coagulation Factors