title: Minocycline-associated tooth discoloration in young adults.
abstract: After observing a patient with adult-onset tooth discoloration coincident with minocycline administration, we retrospectively surveyed a cohort of patients with severe cystic acne during therapeutic trials with isotretinoin. Four of 72 patients who had minocycline therapy during adolescence were found to have minocycline-associated tooth discoloration, which occurred in one case after only four weeks of treatment. Thus, minocycline must be considered as an uncommon cause of tooth staining in adults.
authors.forename: S C
authors.initials: SC
authors.lastname: Poliak
authors.forename: J J
authors.initials: JJ
authors.lastname: DiGiovanna
authors.forename: E G
authors.initials: EG
authors.lastname: Gross
authors.forename: G
authors.initials: G
authors.lastname: Gantt
authors.forename: G L
authors.initials: GL
authors.lastname: Peck
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy / Q000473:pathology; D000293:Adolescent; D000328:Adult; D006801:Humans; D008297:Male; D008911:Minocycline / Q000009:adverse effects*; D012189:Retrospective Studies; D012880:Skin Pigmentation / Q000187:drug effects; D013754:Tetracyclines / Q000009:adverse effects*; D014075:Tooth Discoloration / Q000139:chemically induced*
chemical_list: D013754:Tetracyclines; D008911:Minocycline