Cyclin/PCNA is a cell cycle modulated nuclear protein with a role in DNA replication.
Cyclin/PCNA (auxiliary protein of DNA polymerase delta) is a proliferation sensitive DNA replication protein whose synthesis is modulated during the cell cycle. All available information suggests that cyclin/PCNA may trigger DNA replication following the formation of pre-replicative complexes at the G1/S transition border.
Celis
J E
JE
Department of Medical Biochemistry, Aarhus University, Denmark.
Madsen
P
P
Nielsen
H V
HV
Gesser
B
B
Rasmussen
H H
HH
Cruger
D
D
D002478:Cells, Cultured; D004261:DNA Replication; D005347:Fibroblasts / Q000378:metabolism; D006801:Humans; D007399:Interphase; D009687:Nuclear Proteins / Q000096:biosynthesis*; D018809:Proliferating Cell Nuclear Antigen
D009687:Nuclear Proteins; D018809:Proliferating Cell Nuclear Antigen