[Neuroanatomical dissociation of reinforcing and analgetic effects of morphine].
Pain-relieving and reinforcing effects of morphine after microinjections into brain structures have been studied. Reinforcing effects were revealed after administration into n. accumbens, while analgesic--after injections into periventricular area of the midbrain and dorsomedial hypothalamus. Data obtained demonstrate neurotopographic heterogeneity of two important effects of morphine.
Morozova
A S
AS
Patkina
N A
NA
Zvartau
E E
EE
D000818:Animals; D001921:Brain / Q000187:drug effects*; D004302:Dorsomedial Hypothalamic Nucleus / Q000187:drug effects; D007026:Hypothalamic Area, Lateral / Q000187:drug effects; D008297:Male; D009020:Morphine / Q000008:administration & dosage / Q000494:pharmacology*; D009714:Nucleus Accumbens / Q000187:drug effects; D010487:Periaqueductal Gray / Q000187:drug effects; D051381:Rats
D009020:Morphine
Neĭroanatomicheskaia dissotsiatsiia podkrepliaiushchego i anal'geticheskogo éffektov morfina.