Homogentisic acid determined in biological fluids by HPLC.
In this rapid, specific, and sensitive high-performance liquid-chromatographic method of analysis for homogentisic acid in biological fluids, homogentisic acid is separated on a column of Nucleosil CN. This method, which we applied to the diagnosis of three cases of alcaptonuria, represents a suitable analytical tool for the diagnosis of alcaptonuria.
Bory
C
C
Lab. de Biochimie, Hôpital Debrousse, Lyon, France.
Boulieu
R
R
Chantin
C
C
Mathieu
M
M
D000328:Adult; D000474:Alkaptonuria / Q000175:diagnosis; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006713:Homogentisic Acid / Q000032:analysis* / Q000097:blood / Q000652:urine; D006801:Humans; D008297:Male; D008875:Middle Aged
D006713:Homogentisic Acid