Immunohistochemical demonstration of tyrosine hydroxylase (TH)-positive but dopamine beta-hydroxylase (DBH)-negative neuron-like cells in the pineal gland of golden hamsters.
Double immunostaining for tyrosine hydroxylase (TH) and dopamine beta-hydroxylase (DBH) in the pineal gland revealed many TH-positive but DBH-negative, neuron-like cells in golden hamsters, but not in rats and gerbils. They were scattered in the meshwork of TH- and DBH-positive nerve fibers throughout the parenchyma. Their cell bodies were oval or spindle-shaped (maximum diameter: 15-20 micron). They had sometimes one or two short cell processes. Bilateral superior cervical ganglionectomy diminished strikingly the number of TH- and DBH-positive nerve fibers, but did not affect the number of TH-positive cells.
Jin
K L
KL
Department of Neuroanatomy, Osaka University Medical School, Japan.
Shiotani
Y
Y
Kawai
Y
Y
Kiyama
H
H
D000818:Animals; D006224:Cricetinae; D004299:Dopamine beta-Hydroxylase / Q000032:analysis*; D005728:Ganglia, Sympathetic / Q000166:cytology / Q000201:enzymology; D005849:Gerbillinae; D007150:Immunohistochemistry; D008297:Male; D009412:Nerve Fibers / Q000032:analysis; D009434:Neural Pathways / Q000032:analysis; D010870:Pineal Gland / Q000166:cytology / Q000201:enzymology*; D051381:Rats; D014446:Tyrosine 3-Monooxygenase / Q000032:analysis*
D014446:Tyrosine 3-Monooxygenase; D004299:Dopamine beta-Hydroxylase