title: Ultrasound-induced damage of veins in pig ears, as revealed by scanning electron microscopy.
abstract: Pig ear veins have been treated in situ with ultrasound at a frequency of 750 kHz and intensity of 1.5 W cm-2 (spatial average) during which the temperature in the surrounding tissues rose to 52-54 degrees C. The veins were examined by scanning electron microscopy. Gaps developed between the endothelial cells, which showed many fine perforations in their membranes. Extensive blood clots were observed in which erythrocytes had become more spherical and showed damaged membranes. Effects on membranes were also found with HeLa cells heated to 50 degrees C, and have been previously described by others in heat-treated blood vessels.
authors.affiliation: Department of Bacteriology, University of Aberdeen, Foresterhill, Scotland.
authors.forename: C L
authors.initials: CL
authors.lastname: Kerr
authors.forename: D W
authors.initials: DW
authors.lastname: Gregory
authors.forename: K K
authors.initials: KK
authors.lastname: Chan
authors.forename: D J
authors.initials: DJ
authors.lastname: Watmough
authors.forename: D N
authors.initials: DN
authors.lastname: Wheatley
mesh_terms: D000818:Animals; D004431:Ear, External / Q000098:blood supply*; D004730:Endothelium, Vascular / Q000293:injuries / Q000648:ultrastructure*; D008855:Microscopy, Electron, Scanning; D013552:Swine; D014465:Ultrasonics / Q000009:adverse effects*; D014680:Veins / Q000293:injuries* / Q000648:ultrastructure