Amebic liver abscess and circulating immune complexes of Entamoeba histolytica proteins.
An enzyme-linked immunosorbent assay (ELISA) has been developed to detect amebic antigen in polyethylene-glycol-precipitable circulating immune complexes. Seventy-nine percent of 191 patients with amebic liver abscesses and 46% of 26 Entamoeba histolytica cyst passers had positive tests. None of the samples from 43 apparently healthy controls, 8 patients with past amebic liver abscesses or 31 patients with Giardia lamblia infections were positive. One patient out of 32 with viral hepatitis and 1 patient out of 27 with intestinal tuberculosis had positive tests.
Gandhi
B M
BM
Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.
Irshad
M
M
Acharya
S K
SK
Tandon
B N
BN
D000818:Animals; D000936:Antigen-Antibody Complex / Q000032:analysis*; D000953:Antigens, Protozoan / Q000032:analysis*; D011232:Chemical Precipitation; D004748:Entamoeba histolytica / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D008101:Liver Abscess, Amebic / Q000276:immunology*; D011092:Polyethylene Glycols; D011237:Predictive Value of Tests
D000936:Antigen-Antibody Complex; D000953:Antigens, Protozoan; D011092:Polyethylene Glycols