title: Ventilation-perfusion imaging in evaluating regional lung function in nonpenetrating injury to the chest.
abstract: The extent of chest wall and lung injury after nonpenetrating injury to the chest (NIC) determine how aggressive and invasive management modalities should be. We investigated the value of ventilation (133Xe) and perfusion (99mTc) studies as indicators of extent of lung injury in 28 patients with moderate to severe unilateral NIC. The ventilation-perfusion (V/Q) abnormalities were compared with parameters conventionally used to evaluate NIC. All studies were carried out within 24 h of NIC and repeated 24 h later. Ventilation (p less than 0.001) and perfusion (p less than 0.01) abnormalities were more extensive soon after NIC than suggested by chest roentgenograms. Chest x-ray film changes lagged behind V/Q changes on admission and also after 24 h. The extent of ventilation, perfusion, and chest x-ray film abnormalities on admission were all predictors of increased morbidity. V/Q studies may be useful to define the extent as well as the changes in regional lung function following NIC.
authors.affiliation: Respiratory Intensive Care Unit, Tygerberg Hospital, Republic of South Africa.
authors.forename: S F
authors.initials: SF
authors.lastname: Van Eeden
authors.forename: J F
authors.initials: JF
authors.lastname: Klopper
authors.forename: B
authors.initials: B
authors.lastname: Alheit
authors.forename: P G
authors.initials: PG
authors.lastname: Bardin
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D008168:Lung / Q000000981:diagnostic imaging / Q000503:physiopathology*; D055370:Lung Injury; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011877:Radionuclide Imaging; D012720:Severity of Illness Index; D013898:Thoracic Injuries / Q000000981:diagnostic imaging / Q000503:physiopathology*; D014692:Ventilation-Perfusion Ratio; D014949:Wounds, Nonpenetrating / Q000000981:diagnostic imaging / Q000503:physiopathology*