title: A community-based study of parental age at the birth of patients with dementia of the Alzheimer type.
abstract: The association of dementia of the Alzheimer type (DAT) with parental age at the birth of patients who develop DAT was investigated in a community-based study in Japan. Both maternal and paternal ages of patients who have developed DAT are significantly higher than those in controls and multi-infarct dementia. This study suggests that advanced age may become a cause of chromosome abnormality, and advanced parental age at subjects' birth may be a possible risk factor in DAT.
authors.affiliation: Division of Neurology, Tottori University School of Medicine, Yonago, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Urakami
authors.forename: Y
authors.initials: Y
authors.lastname: Adachi
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000453:epidemiology / Q000235:genetics*; D015161:Dementia, Multi-Infarct / Q000235:genetics; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D008423:Maternal Age; D010331:Paternal Age; D012307:Risk Factors