Intestinal first-pass metabolism of phenacetin in rabbits pretreated orally and intraperitoneally with 3,4-benzpyrene.
Podder
S K
SK
Faculty of Pharmaceutical Sciences, Nagasaki University, Japan.
Nakamura
J
J
Sasaki
H
H
Shibasaki
J
J
D000082:Acetaminophen / Q000031:analogs & derivatives / Q000097:blood; D000284:Administration, Oral; D000818:Animals; D001564:Benzo(a)pyrene / Q000008:administration & dosage* / Q000494:pharmacology; D004790:Enzyme Induction / Q000187:drug effects; D007274:Injections, Intraperitoneal; D007413:Intestinal Mucosa / Q000378:metabolism*; D007421:Intestine, Small / Q000187:drug effects* / Q000201:enzymology; D008642:Mesenteric Veins; D010615:Phenacetin / Q000097:blood / Q000378:metabolism*; D011817:Rabbits
D001564:Benzo(a)pyrene; D000082:Acetaminophen; C037386:acetaminophen glucuronide; D010615:Phenacetin