title: [Effect of the tripeptide melanostatin on the electrical activity of surviving slices of the olfactory cortex in the rat brain].
abstract: The effects of melanostatin (MST 10(-5) M) on transmission in the lateral olfactory tract--superficial pyramidal neurons synapses, were investigated in slices of the rat olfactory cortex. Within 3-6 min after MST addition, the EPSP amplitudes were depressed and then increased (within 6-9 to 30 min); spikes and IPSPs appeared during the latter period. The recovery of the FPs to control values at washing was slow (40-60 min). Possible mechanisms of the MST long-term excitatory effect on neural elements of the slices, are discussed.
authors.forename: A A
authors.initials: AA
authors.lastname: Mokrushin
authors.forename: T R
authors.initials: TR
authors.lastname: Bagaeva
authors.forename: I A
authors.initials: IA
authors.lastname: Gerasimova
authors.forename: N A
authors.initials: NA
authors.lastname: Emel'ianov
authors.forename: M I
authors.initials: MI
authors.lastname: Mitiushov
mesh_terms: D000818:Animals; D002490:Central Nervous System / Q000187:drug effects*; D004558:Electric Stimulation; D005071:Evoked Potentials / Q000187:drug effects; D009075:MSH Release-Inhibiting Hormone / Q000494:pharmacology*; D008297:Male; D008839:Microelectrodes; D009433:Neural Inhibition / Q000187:drug effects; D009833:Olfactory Pathways / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D009435:Synaptic Transmission / Q000187:drug effects; D014022:Tissue Survival / Q000187:drug effects
chemical_list: D009075:MSH Release-Inhibiting Hormone
vernacular_title: Vliianie tripeptida melanostatina na élektricheskuiu aktivnost' perezhivaiushchikh srezov oboniatel'noĭ kory mozga krys.