Antioxidant modulation of phacoanaphylactic endophthalmitis.
Catalase treatment reduces the expected inflammation in experimental phacoanaphylactic endophthalmitis. Catalase is a scavenger of hydrogen peroxide and presumably protects against the cytolytic effects of reactive oxygen metabolites. Recent work indicates that oxygen-derived free radicals may play a critical role in the early tissue damage in immune complex disease.
Marak
G E
GE
Rao
N A
NA
Scott
J M
JM
Duque
R
R
Ward
P A
PA
D000818:Animals; D002374:Catalase / Q000494:pharmacology*; D009877:Endophthalmitis / Q000188:drug therapy* / Q000209:etiology; D007105:Immune Complex Diseases / Q000150:complications*; D007249:Inflammation / Q000188:drug therapy; D008297:Male; D051381:Rats
D002374:Catalase