title: Postmenopausal endometrial patterns and serum estradiol concentrations.
abstract: Eighty postmenopausal women were subjected to endometrial biopsy. Inadequate biopsy was recorded in 30 cases. In the remaining cases (n = 50) the correlation between endometrial patterns and serum estradiol (E2) was performed. These cases were presenting with uterine bleeding (n = 38) or minor gynecological symptoms (n = 12). Proliferative endometrium was the predominant endometrial pattern whereas endometrial malignancy was only present in 15.8% of the bleeding cases. Serum E2 was significantly elevated in cases having malignant endometrium or adenomatous hyperplasia compared to cases having other endometrial patterns. Serum E2 measurement is recommended as a simple screening test for the detection of postmenopausal endometrial hyperplasia and/or malignancy.
authors.affiliation: Department of Gynaecology, Alexandria University, Egypt.
authors.forename: A A
authors.initials: AA
authors.lastname: Ismail
authors.forename: M
authors.initials: M
authors.lastname: Ramadan
authors.forename: A
authors.initials: A
authors.lastname: Soliman
authors.forename: A
authors.initials: A
authors.lastname: Rahmy
authors.forename: A
authors.initials: A
authors.lastname: Rizk
mesh_terms: D001706:Biopsy; D004714:Endometrial Hyperplasia / Q000175:diagnosis / Q000473:pathology; D004717:Endometrium / Q000473:pathology*; D004958:Estradiol / Q000097:blood*; D005260:Female; D006801:Humans; D008593:Menopause / Q000097:blood*; D008875:Middle Aged; D012307:Risk Factors; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000473:pathology
chemical_list: D004958:Estradiol