title: Mechanism of F1-ATPase studied by the genetic approach.
abstract: E. coli F1-ATPase has been studied mainly by the genetic approach. Mutations in either the alpha or beta subunit modified the kinetics of multisite and uni-site hydrolysis of ATP. The mechanism of F1-ATPase and the essential amino acid residues of beta subunits are discussed.
authors.affiliation: Department of Organic Chemistry and Biochemistry, Osaka University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Futai
authors.forename: T
authors.initials: T
authors.lastname: Noumi
authors.forename: M
authors.initials: M
authors.lastname: Maeda
mesh_terms: D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics; D046911:Macromolecular Substances; D009154:Mutation; D006180:Proton-Translocating ATPases / Q000235:genetics* / Q000378:metabolism
chemical_list: D046911:Macromolecular Substances; D006180:Proton-Translocating ATPases