Reflex epilepsy and nonketotic hyperglycemia in the elderly: a specific neuroendocrine syndrome.
We present five elderly patients with focal reflex or posture-induced seizures and nonketotic hyperglycemia (NKH). Each patient exhibited interictal focal findings, such as hemiparesis or hemisensory or aphasic deficits. With control of the hyperglycemia, the seizures stopped, and the neurologic deficits resolved. The syndrome of focal reflex epilepsy and neurologic deficits in the elderly is transient and almost invariably related to NKH, thus representing a specific neuroendocrine syndrome.
Brick
J F
JF
Department of Neurology, West Virginia University School of Medicine, Morgantown 26506.
Gutrecht
J A
JA
Ringel
R A
RA
D000368:Aged; D001921:Brain / Q000503:physiopathology; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D006943:Hyperglycemia / Q000150:complications* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012018:Reflex / Q000502:physiology; D013577:Syndrome