Plain bupivacaine: 0.5% or 0.25% for spinal analgesia?
Plain 0.5% bupivacaine 3 ml was compared with plain 0.25% bupivacaine 6 ml for spinal anaesthesia during transurethral surgery in 40 patients. The solutions were injected over 30 s at the L3/4 space with the patient in the sitting position. The patient was kept sitting for 2 min, supine for 5 min and then placed in the lithotomy position. No significant differences were found in onset time, extent of cephalad spread, duration of sensory or motor blockade, or side effects. The use of a 0.5% plain solution of bupivacaine did not appear to confer any advantage over the 0.25% solution.
Nielsen
T H
TH
Department of Anaesthesia, University Hospital of Aarhus, Denmark.
Kristoffersen
E
E
Olsen
K H
KH
Larsen
H V
HV
Husegaard
H C
HC
Wernberg
M
M
D000368:Aged; D000775:Anesthesia, Spinal; D002045:Bupivacaine / Q000008:administration & dosage* / Q000494:pharmacology; D004341:Drug Evaluation; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000187:drug effects; D011468:Prostatectomy; D013997:Time Factors
D002045:Bupivacaine