A randomized comparison between midazolam and thiopental for elective cesarean section anesthesia: II. Neonates.
In a randomized blind trial, the general condition of 40 neonates was assessed following midazolam- or thiopental-based general anesthesia for elective cesarean section. Among 19 neonatal neurobehavioral observations and tests, statistically significant differences between the midazolam and the thiopental groups were rare. However, a statistically significant interaction with regard to body temperature, general body tone, and arm recoil was observed where results were inferior for midazolam, although only within the first 2 hours. It was concluded that midazolam is as safe as thiopental for the induction and maintenance of elective cesarean section anesthesia in neonates.
Ravlo
O
O
Department of Anesthesiology, Esbjerg Central Hospital, Denmark.
Carl
P
P
Crawford
M E
ME
Bach
V
V
Mikkelsen
B O
BO
Nielsen
H K
HK
D000773:Anesthesia, Obstetrical / Q000379:methods*; D002585:Cesarean Section; D005260:Female; D005333:Fetus / Q000187:drug effects*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008874:Midazolam / Q000009:adverse effects*; D011897:Random Allocation; D013874:Thiopental / Q000009:adverse effects*
D013874:Thiopental; D008874:Midazolam