Small round cell neoplasm of jaw in a patient with medulloblastoma.
A 24-year-old woman presented with a painful mandibular swelling 6 months after multimodality treatment for a cerebellar medulloblastoma. The tumor was microscopically identical to the cranial neoplasm and a part of widespread dissemination as determined by ancillary studies. Previous concepts of the nonmetastasizing nature of intracranial neuroectodermal neoplasms have been modified by studies on treated cases, surgery being considered a virtual prerequisite for this occurrence. Extracranial neoplastic development of a PNET of CNS origin must be considered in disease-free treated patients up to several years after initial therapy.
Richardson
J
J
Department of Oral Pathology, Goldman School of Graduate Dentistry, Boston University Medical Center, MA 02118.
Feldman
M
M
Davis
R
R
D000328:Adult; D002528:Cerebellar Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008339:Mandibular Neoplasms / Q000473:pathology / Q000556:secondary*; D008527:Medulloblastoma / Q000473:pathology / Q000556:secondary*