Hypothalamic axons terminate on forebrain cholinergic neurons: an ultrastructural double-labeling study using PHA-L tracing and ChAT immunocytochemistry.
A correlated light and electron microscopic study combining choline acetyltransferase immunocytochemistry with anterograde tracing of Phaseolus vulgaris leucoagglutinin revealed that axons of lateral hypothalamic neurons terminate on forebrain cholinergic projection cells. This finding is discussed in relation to direct and indirect corticopetal systems.
Zaborszky
L
L
Department of Otolaryngology, University of Virginia School of Medicine, Charlottesville 22908.
Cullinan
W E
WE
D000818:Animals; D002795:Choline O-Acetyltransferase / Q000378:metabolism; D002799:Cholinergic Fibers / Q000201:enzymology / Q000648:ultrastructure*; D005625:Frontal Lobe / Q000648:ultrastructure*; D007026:Hypothalamic Area, Lateral / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D009411:Nerve Endings / Q000648:ultrastructure*; D009434:Neural Pathways / Q000033:anatomy & histology; D010835:Phytohemagglutinins; D051381:Rats; D011919:Rats, Inbred Strains
D010835:Phytohemagglutinins; D002795:Choline O-Acetyltransferase