title: Repair of tympanic membrane perforations using hyaluronic acid: an alternative to myringoplasty.
abstract: Fifteen dry, small or medium-sized tympanic membrane perforations were treated by local application of 1 per cent hyaluronic acid after excision of the perforation rim. The duration of the perforations ranged from two months to ten years. Fourteen of the perforations were covered within 15 +/- 7.4 (S.D.) days and 5 +/- 2.4 (S.D.) applications were needed to achieve closure. Hyaluronic acid treatment of dry tympanic membrane perforations not exceeding one quadrant seems to be an alternative to surgical myringoplasty.
authors.affiliation: University of Tromsø, Norway.
authors.forename: L E
authors.initials: LE
authors.lastname: Stenfors
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D012421:Rupture; D014432:Tympanic Membrane / Q000293:injuries*
chemical_list: D006820:Hyaluronic Acid