title: Photodynamic therapy with haematoporphyrin derivative on mice with solid Ehrlich carcinomas.
abstract: The tumor-toxic effect of the photosensitizer HpD/Halle activated by laser radiation was demonstrated. Solid Ehrlich carcinoma was used as model. Investigations into the tumor growth, the HpD-distribution after different kinds of drug administration by means of fluorescence measurements, the phototoxicity and the reduction of tumor masses after HpD application and laser irradiation were carried out.
authors.affiliation: Department of Physics, Friedrich-Schiller University Jena, GDR.
authors.forename: K
authors.initials: K
authors.lastname: König
authors.forename: V
authors.initials: V
authors.lastname: Bockhorn
authors.forename: U
authors.initials: U
authors.lastname: Krause
authors.forename: W
authors.initials: W
authors.lastname: Dietel
authors.forename: H
authors.initials: H
authors.lastname: Schubert
authors.forename: P
authors.initials: P
authors.lastname: Lotz
authors.forename: L P
authors.initials: LP
authors.lastname: Löbe
mesh_terms: D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy*; D005260:Female; D006414:Hematoporphyrin Photoradiation; D008297:Male; D009368:Neoplasm Transplantation; D010778:Photochemotherapy