title: The clinical pattern of duodenogastric bile reflux in the Kenyan Africans.
abstract: Forty consecutive African patients found to have duodenogastric bile reflux at endoscopy were studied. Bile reflux was found more commonly among males than females, giving a male/female ratio of 2.3:1, with a peak age at 41-60 years. ABO blood groups had no significant influence on duodenogastric bile reflux. Flatulence and borborygmi were the most consistent symptoms other than the classical dyspeptic pain pattern. Bilious vomiting was a rare finding. Duodenogastric bile reflux was more commonly associated with endoscopic gastritis (67.5%), gastric ulcer (35%) and oesophagitis (30%) than with duodenal ulcer (22.5%), deformed pyloric ring (5%) or distorted duodenal bulb (2.5%). The dysfunction in the pyloric sphincter in people with duodenogastric bile reflux appears to be more of a physiological defect than structural.
authors.forename: E O
authors.initials: EO
authors.lastname: Ogutu
authors.forename: G N
authors.initials: GN
authors.lastname: Lule
authors.forename: F
authors.initials: F
authors.lastname: Okoth
authors.forename: S J
authors.initials: SJ
authors.lastname: Mwai
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001655:Bile Reflux / Q000473:pathology*; D001660:Biliary Tract Diseases / Q000473:pathology*; D003906:Developing Countries; D004386:Duodenum / Q000473:pathology; D004724:Endoscopy; D004947:Esophagus / Q000473:pathology; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D007630:Kenya; D008297:Male; D008875:Middle Aged