title: Urethral syndrome. A comparison of different treatment modalities.
abstract: Sixty women with the diagnosis of urethral syndrome were consecutively assigned to one of three treatment modalities. The first group (20 patients) was treated with tetracycline, 2 g/d for ten days. The second group (20 patients) was treated with three serial urethral dilations at two- to three-week intervals, and the third group (20 patients) received placebo for ten days and served as a control group. A detailed clinical evaluation and uroflowmetry were performed before treatment and eight weeks afterwards. A subjective cure, which was defined as an absence of symptoms at the follow-up visits, was achieved in 20% of the placebo group, 50% of the tetracycline group and 75% of the urethral dilation group (P less than .01). An objective improvement in uroflowmetry occurred only in the group treated with serial urethral dilation.
authors.affiliation: Department of Obstetrics and Gynecology, Harbor-University of California, Los Angeles Medical Center, Torrance 90509.
authors.forename: A
authors.initials: A
authors.lastname: Bergman
authors.forename: M
authors.initials: M
authors.lastname: Karram
authors.forename: N N
authors.initials: NN
authors.lastname: Bhatia
mesh_terms: D000328:Adult; D004106:Dilatation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies; D011795:Surveys and Questionnaires; D013577:Syndrome; D013752:Tetracycline / Q000627:therapeutic use*; D014522:Urethral Diseases / Q000628:therapy*; D014555:Urination Disorders / Q000628:therapy*
chemical_list: D013752:Tetracycline