title: Aneurysms of the sinuses of Valsalva in Noonan's syndrome.
abstract: A case of Noonan's syndrome with aneurysmal dilatation of the sinuses of Valsalva is described. Enlargement of the left heart border on the postero-anterior chest radiograph was initially interpreted as dilatation of main pulmonary artery but aortography confirmed the presence of large aneurysms of two of the sinuses of Valsalva. Connective tissue abnormalities, known to occur in Noonan's syndrome, could be responsible for aortic abnormalities in this syndrome.
authors.affiliation: Cardiac Department, Brompton Hospital, London, UK.
authors.forename: J M
authors.initials: JM
authors.lastname: Morgan
authors.forename: M O
authors.initials: MO
authors.lastname: Coupe
authors.forename: M
authors.initials: M
authors.lastname: Honey
authors.forename: G A
authors.initials: GA
authors.lastname: Miller
mesh_terms: D000328:Adult; D001014:Aortic Aneurysm / Q000150:complications* / Q000000981:diagnostic imaging; D001027:Aortography; D003951:Diagnostic Errors; D006801:Humans; D008297:Male; D009634:Noonan Syndrome / Q000150:complications*; D012850:Sinus of Valsalva