[A case-control study of stomach cancer in young females, with special reference to the effects of pregnancy and delivery].
To investigate the effects of pregnancy and delivery on stomach carcinogenesis, we have conducted a case-control study. The cases consisted of females aged 34 or below who had been histologically diagnosed as having a stomach cancer, covering a period from 1967 to 1986 at the Center for Adult Diseases, Osaka. Our birth-year-matched controls were selected from female examinees who had undergone a gastroendoscopy in 1986. In this manner, a total of 79 cases and 158 controls were obtained. For women in the age group from 30 to 34, a history of their pregnancies and deliveries seemed to have protective effects on stomach carcinogenesis (RR = 0.36, P less than 0.05), whereas for those in the age group under 30, it appeared to be a risk factor for stage IV stomach cancer (RR = 4.42, P less than 0.05).
Tsukuma
H
H
Department of Field Research, Center for Adult Diseases, Osaka.
Fujimoto
I
I
Furukawa
H
H
Iwanaga
T
T
Okuda
S
S
Tatsuta
M
M
Oshima
A
A
D000328:Adult; D000428:Alcohol Drinking; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D007743:Labor, Obstetric; D011247:Pregnancy; D011336:Probability; D012307:Risk Factors; D012907:Smoking; D013274:Stomach Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000235:genetics