Methemoglobinemia and hemolytic anemia after phenazopyridine hydrochloride (Pyridium) administration in end-stage renal disease.
Phenazopyridine is a commonly used urinary tract analgesic. As illustrated by the case we have reported, its use may be complicated by the development of methemoglobinemia and hemolytic anemia, especially in patients with renal insufficiency.
Fincher
M E
ME
Department of Medicine, Medical College of Georgia, Augusta 30912-2623.
Campbell
H T
HT
D000208:Acute Disease; D000328:Adult; D000631:Aminopyridines / Q000009:adverse effects*; D000743:Anemia, Hemolytic / Q000139:chemically induced*; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008297:Male; D008708:Methemoglobinemia / Q000139:chemically induced* / Q000188:drug therapy; D008751:Methylene Blue / Q000627:therapeutic use; D010621:Phenazopyridine / Q000009:adverse effects*
D000631:Aminopyridines; D010621:Phenazopyridine; D008751:Methylene Blue