title: L-tryptophan in neuroleptic-induced tardive dyskinesia.
abstract: Administration of the serotonin precursor L-tryptophan in a patient with neuroleptic-induced tardive dyskinesia, produced a dramatic reduction in the severity of the abnormal movements within 24 hours. This report supports our hypothesis that alterations in the function of serotoninergic neurotransmission are implicated in the pathophysiology of neuroleptic-induced tardive dyskinesia.
authors.affiliation: Department of Neurology, Pharmacology and Toxicology, University of Arizona, Tucson 86724.
authors.forename: R
authors.initials: R
authors.lastname: Sandyk
authors.forename: C R
authors.initials: CR
authors.lastname: Bamford
authors.forename: I
authors.initials: I
authors.lastname: Khan
authors.forename: H
authors.initials: H
authors.lastname: Fisher
mesh_terms: D014150:Antipsychotic Agents / Q000009:adverse effects*; D004409:Dyskinesia, Drug-Induced / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D014364:Tryptophan / Q000627:therapeutic use*
chemical_list: D014150:Antipsychotic Agents; D014364:Tryptophan