title: [An autopsied case of idiopathic interstitial pneumonia, showing a remarkably elevated serum level of CA 19-9].
abstract: Discussed herein is an autopsied case of a 30-year-old male with Idiopathic Interstitial Pneumonia (IIP) manifesting a markedly elevated CA 19-9 in the serum (maximum, over 120,000 U/ml). Despite a careful examination, no malignant lesion was found. The postmortem examination revealed a marked elevation of CA 19-9 in the serum and in the lung tissue. Further immunohistochemically regenerative bronchiolar and alveolar epithelial cells were more intensely positive for CA 19-9 than in our controls. These CA 19-9 positive cells for the most part, were found to stain with alcian blue. It is considered that IIP induces activation of sialyl-transferase in these cells.
authors.affiliation: Dept. of Pathology, Kagawa Med. School.
authors.forename: T
authors.initials: T
authors.lastname: Okino
authors.forename: I
authors.initials: I
authors.lastname: Yamadori
authors.forename: T
authors.initials: T
authors.lastname: Ogino
authors.forename: H
authors.initials: H
authors.lastname: Miki
authors.forename: E
authors.initials: E
authors.lastname: Hirakawa
authors.forename: T
authors.initials: T
authors.lastname: Morikawa
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: M
authors.initials: M
authors.lastname: Ohmori
authors.forename: M
authors.initials: M
authors.lastname: Bungo
authors.forename: Y
authors.initials: Y
authors.lastname: Yamaji
mesh_terms: D000328:Adult; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis*; D006801:Humans; D008168:Lung / Q000276:immunology / Q000473:pathology*; D008297:Male; D011658:Pulmonary Fibrosis / Q000276:immunology* / Q000473:pathology
chemical_list: D015295:Antigens, Tumor-Associated, Carbohydrate