title: Coexistent cardiac tumours and malformations of the heart.
abstract: Cardiac tumours and anatomical malformations of the heart may produce similar clinical signs and symptoms. The coexistence of these two abnormalities complicates diagnosis and probably adversely affects prognosis. We present a review of four cases of this rare combination. In the first case, Ebstein's malformation was present in a child with tuberous sclerosis and cardiac rhabdomyomata. Right ventricular rhabdomyomata were associated with a hypoplastic tricuspid valve in the second case. In the third case, cardiac myxomas were detected in a child with a double-chambered right ventricle. The fourth case was a child with a fibroma of the right ventricle with pulmonary atresia. We propose that, in some circumstances, a space-occupying lesion may be associated with, or possibly induce, a malformation within the developing heart.
authors.affiliation: Department of Paediatric Pathology, Bristol Maternity Hospital, U.K.
authors.forename: G A
authors.initials: GA
authors.lastname: Russell
authors.forename: J P
authors.initials: JP
authors.lastname: Dhasmana
authors.forename: P J
authors.initials: PJ
authors.lastname: Berry
authors.forename: E F
authors.initials: EF
authors.lastname: Gilbert-Barness
mesh_terms: D004437:Ebstein Anomaly / Q000473:pathology; D005260:Female; D005313:Fetal Death / Q000473:pathology; D005350:Fibroma / Q000151:congenital; D006325:Heart Atria / Q000473:pathology; D006330:Heart Defects, Congenital / Q000473:pathology*; D006338:Heart Neoplasms / Q000151:congenital* / Q000473:pathology; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009232:Myxoma / Q000151:congenital; D011247:Pregnancy; D012207:Rhabdomyoma / Q000151:congenital; D014402:Tuberous Sclerosis / Q000151:congenital