Proarrhythmia related to a kinetic and dynamic interaction of mexiletine and theophylline.
Kessler
K M
KM
Department of Medicine, University of Miami School of Medicine, FL.
Interian
A
A
Cox
M
M
Topaz
O
O
De Marchena
E J
EJ
Myerburg
R J
RJ
D001145:Arrhythmias, Cardiac / Q000139:chemically induced* / Q000503:physiopathology; D004347:Drug Interactions; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008801:Mexiletine / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D008875:Middle Aged; D013806:Theophylline / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics
D008801:Mexiletine; D013806:Theophylline