[Quantitative analysis of apolipoproteins and lipoprotein particles in patients with head injuries].
By head-injured patients, apo A-I and apo A-II concentrations were more decreased in HDL3 than in HDL2. Then, the plasmatic concentrations of the main lipoprotein particles present in HDL fraction were modified. For example, a significant decrease of Lp A-I: A-II particles was observed and this variation was similar to that of total apo A-I (r = 0.78). On the other hand, the concentration of Lp A-I particles was slightly modified, apo C-III concentration was markedly decreased whereas apo E concentration was significantly increased (p less than 0.05); in plasma samples obtained 10 days after a severe head injury, apo E reached three times the normal value.
Kabbaj
O
O
Laboratoire de Biochimie Appliquée Université Louis-Pasteur, Strasbourg.
Saile
R
R
Ghalim
N
N
Parra
H J
HJ
Puchois
P
P
Fruchart
J C
JC
Métais
P
P
Férard
G
G
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001053:Apolipoproteins / Q000097:blood*; D006259:Craniocerebral Trauma / Q000097:blood*; D005260:Female; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D001053:Apolipoproteins; D008074:Lipoproteins; D008075:Lipoproteins, HDL; D008079:Lipoproteins, VLDL
Analyse quantitative des apolipoprotéines et des particules lipoprotéiniques chez les traumatisés crâniens.