title: GABA-immunoreactivity in ganglion cells of the rat retina.
abstract: Ganglion cells in the rat retina were labeled with the fluorescent dye, Diamidino-yellow, by retrograde transport from the superior colliculus and subsequently reacted for GABA-like immunoreactivity with a rhodamine-conjugated antiserum. Examination of sectioned retinas by fluorescence microscopy showed double labeling in approximately 6% of the ganglion cells. The presence of GABA in these neurons suggests that they may be involved in providing direct inhibitory input to the rat tectum.
authors.affiliation: Department of Anatomy and Cell Biology, Wayne State University, Detroit, MI 48201.
authors.forename: D M
authors.initials: DM
authors.lastname: Caruso
authors.forename: M T
authors.initials: MT
authors.lastname: Owczarzak
authors.forename: D J
authors.initials: DJ
authors.lastname: Goebel
authors.forename: J C
authors.initials: JC
authors.lastname: Hazlett
authors.forename: R G
authors.initials: RG
authors.lastname: Pourcho
mesh_terms: D000818:Animals; D007150:Immunohistochemistry; D051381:Rats; D012160:Retina / Q000378:metabolism*; D012165:Retinal Ganglion Cells / Q000378:metabolism*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
chemical_list: D005680:gamma-Aminobutyric Acid