[Activation of the DNA repair system in tissues of mice subjected to chronic gamma irradiation].
Mice exposed to gamma-quanta during 47 and 82 days at a dose-rate of 1.3 mGy/h and cumulative doses of 1.45 and 2.54 Gy, respectively, were subsequently subjected to a single acute irradiation with a dose of 20 Gy. Repair of DNA damages induced by the acute exposure was shown to proceed in the brain, pulmonary and splenic tissues of chronically exposed mice more readily than in the tissues of mice not subjected to chronic irradiation. The data obtained indicate that the induced adaptive response activates DNA repair in tissues of mice exposed to long-term low-level radiation.
Kozhanovskaia
Ia K
IaK
Fomenko
L A
LA
Sirota
N P
NP
Gaziev
A I
AI
D000818:Animals; D001921:Brain / Q000528:radiation effects; D002588:Cesium Radioisotopes; D004247:DNA / Q000528:radiation effects*; D004249:DNA Damage; D004260:DNA Repair / Q000528:radiation effects*; D005720:Gamma Rays; D008099:Liver / Q000528:radiation effects; D008168:Lung / Q000528:radiation effects; D008297:Male; D051379:Mice; D013154:Spleen / Q000528:radiation effects; D013997:Time Factors
D002588:Cesium Radioisotopes; D004247:DNA
Aktivatsiia sistemy reparatsii DNK v tkaniakh mysheĭ, podvergnutykh khronicheskomy gamma-oblucheniiu.