Relapse of multiple sclerosis following acute allergic reactions to plasma during plasmapheresis.
In a small pilot study of plasmapheresis in chronic progressive multiple sclerosis, two patients suffered relapses following an acute allergic reaction to plasma. It is suggested that allergic reactions may have played a role in the exacerbation and recommended that fresh frozen plasma be avoided in therapeutic trials for multiple sclerosis.
Wirguin
I
I
Department of Neurology, Hadassah University Hospital, Jerusalem, Israel.
Shinar
E
E
Abramsky
O
O
D000208:Acute Disease; D000328:Adult; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology*; D008297:Male; D009103:Multiple Sclerosis / Q000276:immunology / Q000628:therapy*; D010949:Plasma / Q000276:immunology*; D010956:Plasmapheresis; D012008:Recurrence