Dietary related periodontitis and oro-nasal fistulation in rats.
An outbreak of periodontitis and oro-nasal fistulation in rats in a routine long-term bioassay is described. There was strong circumstantial and pathological evidence that the lesions were caused by long pointed food fibres present in an expanded diet which was fed as a powder.
Robinson
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D000818:Animals; D004032:Diet; D005260:Female; D005402:Fistula / Q000209:etiology* / Q000473:pathology; D008297:Male; D009055:Mouth / Q000473:pathology; D009059:Mouth Diseases / Q000209:etiology* / Q000473:pathology; D009666:Nose / Q000473:pathology; D009668:Nose Diseases / Q000209:etiology* / Q000473:pathology; D010518:Periodontitis / Q000209:etiology* / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains; D013047:Specific Pathogen-Free Organisms