title: Humoral recognition of lipopolysaccharide core antigens of gram-negative bacteria in neonatal swine.
abstract: Serologic recognition of common lipopolysaccharide core antigens has been related to enhanced resistance to gram-negative bacterial disease in several species. Class-specific titers (IgG, IgM) were determined by direct ELISA, using intact Escherichia coli (J5) as a plate antigen. Serum samples were obtained from 224 neonatal swine between the ages of 36 and 60 hours. The mean (+/- SEM) log10 IgG titer against gram-negative core antigens was 1:1,713 +/- 0.4718 and the mean log10 IgM titer was 1:202 +/- 0.5644. The IgG titer was directly related with litter size, birth weight, and serum total IgG concentration; IgM titer was directly related with dam parity and serum total IgG concentration.
authors.affiliation: Department of Clinical Pathology, School of Veterinary Medicine, University of California, Davis 95616.
authors.forename: J W
authors.initials: JW
authors.lastname: Tyler
authors.forename: J S
authors.initials: JS
authors.lastname: Cullor
authors.forename: M C
authors.initials: MC
authors.lastname: Thurmond
authors.forename: D W
authors.initials: DW
authors.lastname: Hird
authors.forename: K M
authors.initials: KM
authors.lastname: Parker
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006090:Gram-Negative Bacteria / Q000276:immunology*; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D008070:Lipopolysaccharides / Q000276:immunology*; D012044:Regression Analysis; D013552:Swine / Q000276:immunology*
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008070:Lipopolysaccharides