The effects of adrenergic agonists and age on lipogenesis in avian hepatocytes.
1. Adrenergic inhibition of lipogenesis was examined in vitro using hepatocytes isolated from chickens 2-9 weeks old. 2. Lipogenesis was inhibited by beta 1, beta 2 and alpha 1 agonists. Greatest inhibition occurred when more than one type of receptor was stimulated. 3. Clonidine (alpha 2-agonist) may have stimulated lipogenesis. 4. Responsiveness to the agonists decreased as the chickens got older.
Harris
R B
RB
Department of Foods and Nutrition, University of Georgia, Athens 30602.
Neal
M J
MJ
Martin
R J
RJ
D000375:Aging / Q000378:metabolism*; D000818:Animals; D002645:Chickens / Q000378:metabolism*; D008055:Lipids / Q000096:biosynthesis*; D008099:Liver / Q000378:metabolism*
D008055:Lipids