Neurohormonal aspects of fibromyalgia syndrome.
There is a growing awareness that fibrositis/fibromyalgia syndrome is a systemic disorder for which a pathogenic mechanism must be sought. A generalized deficiency of the neurotransmitter, serotonin could explain many of fibromyalgia's typical manifestations. The serotonin deficiency hypothesis is appealing because it provides a number of experimental approaches that can now be used to further study the pathogenesis of this disorder.
Russell
I J
IJ
Department of Medicine, University of Texas Health Science Center, San Antonio.
D000818:Animals; D001679:Biogenic Amines / Q000502:physiology; D005356:Fibromyalgia / Q000503:physiopathology*; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology; D008954:Models, Biological; D009490:Neurosecretory Systems / Q000503:physiopathology*; D012701:Serotonin / Q000502:physiology; D013577:Syndrome; D014364:Tryptophan / Q000502:physiology
D001679:Biogenic Amines; D012701:Serotonin; D014364:Tryptophan