Fc and C3b receptor changes on mouse peritoneal leucocytes following stimulation with an extract of Ascaris suum.
Changes in IgG-Fc and IgM-C3b receptors of mouse peritoneal leucocytes after in vivo stimulation with Ascaris suum adult extract were studied. Erythrocyte IgG-Fc rosettes were found to initially be decreased with A. suum stimulated neutrophils, eosinophils and macrophages in comparison with nonstimulated cells. IgG-Fc rosettes then increased with time and remained high for a 60 min exposure time. IgM-C3b rosette formation was lower with A. suum stimulated leucocytes throughout 60 min of exposure and dropped off dramatically after 30 min. Unstimulated leucocytes formed IgM-C3b rosettes sooner and maintained them at higher levels for a longer period of time than stimulated cells.
Laubach
H E
HE
D000818:Animals; D001196:Ascariasis / Q000276:immunology; D001200:Ascaris / Q000276:immunology*; D004804:Eosinophils / Q000276:immunology; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007962:Leukocytes / Q000276:immunology*; D008264:Macrophages / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D009504:Neutrophils / Q000276:immunology; D010587:Phagocytosis; D011951:Receptors, Complement / Q000276:immunology*; D017463:Receptors, Complement 3b; D011961:Receptors, Fc / Q000276:immunology*; D012397:Rosette Formation; D013997:Time Factors
D007074:Immunoglobulin G; D007075:Immunoglobulin M; D011951:Receptors, Complement; D017463:Receptors, Complement 3b; D011961:Receptors, Fc