Tolerance to phenelzine and subsequent refractory depression: three cases.
Three patients with major depression superimposed on chronic dysthymia were treated with phenelzine. After an initial excellent response, each patient relapsed and developed a severe chronic depression that was refractory to other treatments. The implications for the long-term effects of phenelzine treatment are considered.
Donaldson
S R
SR
Department of Psychiatry, St. Elizabeth's Hospital, Boston, MA 02135.
D000328:Adult; D002908:Chronic Disease; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010624:Phenelzine / Q000009:adverse effects / Q000627:therapeutic use*; D012008:Recurrence
D010624:Phenelzine