Chromosomal assignment of a glutamic acid transfer RNA (tRNAGlu) gene to 1p36.
A gene for tRNAGlu has been assigned to human chromosome 1p36 by in situ hybridisation using a [3H]-labelled or biotinylated 2.4-kb (human) DNA fragment containing a tRNAGlu gene as a probe. With the biotinylated DNA probe a secondary statistically significant site of hybridisation was observed at 1q21-22 which might represent a pseudogene or related sequence. In fibroblasts from gorilla (Gorilla gorilla) using biotin labelling, a single site of hybridisation occurred at 1qter which provides further support for homology of 1q in the higher apes and human 1p.
Boyd
E
E
Duncan Guthrie Institute of Medical Genetics, Glasgow, UK.
Theriault
A
A
Goddard
J P
JP
Kalaitsidaki
M
M
Spathas
D H
DH
Connor
J M
JM
D000818:Animals; D001483:Base Sequence; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D015342:DNA Probes; D006071:Gorilla gorilla; D006801:Humans; D007621:Karyotyping; D009693:Nucleic Acid Hybridization; D012345:RNA, Transfer, Amino Acid-Specific / Q000235:genetics*; D012352:RNA, Transfer, Glu / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid
D015342:DNA Probes; D012345:RNA, Transfer, Amino Acid-Specific; D012352:RNA, Transfer, Glu