title: Lymphocyte transformation induced by autologous cells. XVII. Lower autologous mixed lymphocyte reaction in subjects with a history of hayfever.
abstract: The autologous mixed lymphocyte reaction (AMLR) is impaired in patients with a number of diseases associated with abnormal immunoregulation. Since allergic disorders are also associated with abnormal immunoregulation, we assessed the AMLR in individuals with a history of ragweed hayfever. Lymphocytes from allergic subjects had a lower AMLR than nonallergic controls by rank order analysis. These results support the association of abnormal in vivo immunoregulation with reduced AMLR.
authors.forename: D H
authors.initials: DH
authors.lastname: Bovbjerg
authors.forename: V A
authors.initials: VA
authors.lastname: Wang
authors.forename: R
authors.initials: R
authors.lastname: Schwab
authors.forename: K S
authors.initials: KS
authors.lastname: Lebenger
authors.forename: G W
authors.initials: GW
authors.lastname: Siskind
authors.forename: M E
authors.initials: ME
authors.lastname: Weksler
mesh_terms: D006801:Humans; D008213:Lymphocyte Activation; D007959:Lymphocyte Culture Test, Mixed; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology*