title: Evaluation of spinal evoked potentials: a model for assessment of spinal cord function in isolation.
abstract: Spinal evoked potentials were recorded from the dorsal columns of in vitro mouse hemicord preparations. The response of these potentials to different periods of hypoxia was studied. A decrease in amplitude of the potential to 50% and 10% of pre-hypoxia reference occurred after 3.19 +/- 1.36 and 7.3 +/- 2.97 min, respectively. Complete recovery of the potential was seen in specimens exposed to 5 and 10 min of hypoxia. Incomplete recovery occurred with exposure to longer periods of hypoxia. In preparations that remained isoelectric for less than 5 min total recovery was seen.
authors.affiliation: Department of Neurology, University of Louisville School of Medicine.
authors.forename: V
authors.initials: V
authors.lastname: Iyer
authors.forename: K H
authors.initials: KH
authors.lastname: Reid
authors.forename: H
authors.initials: H
authors.lastname: Edmonds
mesh_terms: D000818:Animals; D004558:Electric Stimulation; D005071:Evoked Potentials; D066298:In Vitro Techniques; D051379:Mice; D013116:Spinal Cord / Q000502:physiology*