Complications of uterine cervix carcinoma treatments: the problem of a uniform classification.
Ninety-six articles published in English, French and Italian between 1938 and 1986 have been examined in order to analyze the classifications and reporting methods used by different researchers. Specialty and nationality of authors, classifications used, organs, systems and anatomic sites considered, weight given to the most frequently encountered complications are studied. Fifty-nine papers make no use of classification of complications of any kind, neither by onset time, nor by severity, but simply describe the observed events. The remaining 37 papers use a classification based on varying criteria. Thirty-four authors use a classification by severity according to different criteria; four authors classify complications according to the treatment required. In the remaining 30 papers a true scale is used. A total of 22 classifications emerges from these papers; in eight cases a previously published classification is used. The weight assigned by different authors to specific complications has been compared. The following main points emerge from the analysis: about two authors out of three simply describe the observed complications; 30 rely on a true scale of severity, but 22 different grading systems are used. Most classifications do not cover all possible complications, both surgical and radiotherapeutic, but concentrate on those complications which are typically generated by author's therapeutic approach. Only three take into account complications related to different treatment modalities. The observation period is not standardized: published data derive from follow-up times spanning from some months to many years. Authors mainly focus their interest on gastrointestinal and/or urinary complications; other organs and systems are rarely considered.(ABSTRACT TRUNCATED AT 250 WORDS)
Sismondi
P
P
Istituto di Ginecologia e Ostetricia, Universitá, di Torino, Italy.
Sinistrero
G
G
Zola
P
P
Volpe
T
T
Ferraris
R
R
Castelli
G L
GL
Giai
M
M
D000970:Antineoplastic Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D015201:Meta-Analysis as Topic; D011183:Postoperative Complications; D011878:Radiotherapy / Q000009:adverse effects*; D002583:Uterine Cervical Neoplasms / Q000628:therapy*
D000970:Antineoplastic Agents