title: [An increase in intracranial pressure following fentanyl].
abstract: We report an unusual fentanyl-induced reaction in an 8-year-old boy who had to be sedated and hyperventilated because of a severe head injury. Following the intravenous administration of a bolus of fentanyl, the intracranial pressure rose markedly for about 10 min. Simultaneously, the arterial blood pressure fell and heart rate increased, critically reducing the cerebral perfusion pressure temporarily. This reaction could be due to histamine-induced vasodilation.
authors.affiliation: Abteilung für Anaesthesiologie, Städtische Krankenanstalten Köln-Merheim.
authors.forename: D
authors.initials: D
authors.lastname: Knüttgen
authors.forename: M
authors.initials: M
authors.lastname: Doehn
authors.forename: D
authors.initials: D
authors.lastname: Eymer
authors.forename: M R
authors.initials: MR
authors.lastname: Müller
mesh_terms: D002648:Child; D005283:Fentanyl / Q000009:adverse effects*; D006801:Humans; D007427:Intracranial Pressure / Q000187:drug effects*; D008297:Male; D013268:Stimulation, Chemical
chemical_list: D005283:Fentanyl
vernacular_title: Hirndrucksteigerung nach Fentanyl.