title: Caudal epidural morphine analgesia for an infant with advanced neuroblastoma: report of a case.
abstract: Caudal epidural administration of morphine was used to provide pain relief to a 5-month-old infant with neuroblastoma and massive abdominal distension. Intermittent injections were performed on 6 occasions over 1 week and resulted in prolonged analgesia (17-20 h) and improved depth of respiration on each occasion. Epidural opioid analgesia should be regarded as technically feasible for relief of cancer pain in patients of all ages.
authors.affiliation: Dept. of Anesthesia, Children's Hospital, Boston, MA 02115 U.S.A. Div. of Pediatric Oncology, Children's Hospital, Boston, MA 02115 U.S.A. Dept. of Nursing, Children's Hospital, Boston, MA 02115 U.S.A.
authors.forename: Charles B
authors.initials: CB
authors.lastname: Berde
authors.forename: Nathan
authors.initials: N
authors.lastname: Fischel
authors.forename: Pierre J
authors.initials: PJ
authors.lastname: Filardi
authors.forename: Carrie S
authors.initials: CS
authors.lastname: Coe
authors.forename: Holcombe E
authors.initials: HE
authors.lastname: Grier
authors.forename: Shelly C
authors.initials: SC
authors.lastname: Bernstein
mesh_terms: D015360:Analgesia, Epidural; D003131:Combined Modality Therapy; D006801:Humans; D007223:Infant; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D009020:Morphine; D009447:Neuroblastoma / Q000503:physiopathology / Q000628:therapy*; D059408:Pain Management
chemical_list: D009020:Morphine