title: [Surgical therapy of sporadic and familial pheochromocytoma].
abstract: From 1975 through 1987, 54 patients underwent operations for pheochromocytoma (PCC): 37 patients for sporadic unilateral adrenal PCC, 9 for bilateral and familial PCC, and 4 patients for paraganglioma. In 4 additional patients, laparotomy failed to discover the reason for hypercatecholaminemia. There were no operative mortality and a low morbidity for unilateral (n = 43) as well as for bilateral adrenalectomy (n = 6). To avoid hormone replacement therapy after bilateral total adrenalectomy at least for some years, unilateral instead of bilateral adrenalectomy was preferred to be the initial surgical procedure of choice for familial and MEN-IIA-associated unilateral adrenal PCC. Autologous transplantation of the adrenal cortex were performed in 2 patients after bilateral adrenalectomy. 6 months postoperatively, the transplants were vital as proved by light-microscopy, but sufficiently functioning only in 1 patient.
authors.affiliation: Klinik für Abdominal- und Transplantationschirurgie, Medizinischen Hochschule Hannover, BRD.
authors.forename: H
authors.initials: H
authors.lastname: Dralle
authors.forename: M
authors.initials: M
authors.lastname: Ipta
authors.forename: E
authors.initials: E
authors.lastname: Henschel
authors.forename: T
authors.initials: T
authors.lastname: Schürmeyer
authors.forename: H
authors.initials: H
authors.lastname: Grosse
authors.forename: K F
authors.initials: KF
authors.lastname: Gratz
authors.forename: J
authors.initials: J
authors.lastname: Kemnitz
authors.forename: A
authors.initials: A
authors.lastname: von zur Mühlen
mesh_terms: D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000235:genetics / Q000601:surgery*; D000311:Adrenal Glands / Q000637:transplantation; D000315:Adrenalectomy; D000328:Adult; D000368:Aged; D004837:Epinephrine / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009377:Multiple Endocrine Neoplasia / Q000235:genetics; D009378:Neoplasms, Multiple Primary / Q000601:surgery; D009638:Norepinephrine / Q000097:blood; D010673:Pheochromocytoma / Q000235:genetics / Q000601:surgery*
chemical_list: D009638:Norepinephrine; D004837:Epinephrine
vernacular_title: Operative Therapie des sporadischen und familiären Phäochromozytoms.