Is there an increased incidence of adenomatous polyps in breast cancer patients?
Using flexible proctosigmoidoscopy, the incidence of adenomatous polyps was studied in 161 patients previously operated on for breast cancer and also in 147 hospitalized controls not presenting with colorectal symptoms. The acceptance and tolerance of the examination were good in both populations. The mean age and length of the colons explored were not statistically different for the two groups. The incidence of adenomas was high in the breast cancer group (14.2%) in comparison to the control group (4.7%) (P less than 0.01). This strong incidence especially concerned very small polyps with a diameter smaller than 3 mm. There were also two polyps with superficial carcinomas in the breast cancer group. Breast cancer does indeed seem to represent a condition with a high risk of colorectal adenomas. Our results prompt us to propose the adoption of systematic screening measures and a surveillance schedule as soon as the breast cancer is found.
Jouin
H
H
Service d'Hépato-Gastroentérologie et d'Assistance Nutritive, Chu Hautepierre, Strasbourg, France.
Baumann
R
R
Derlon
A
A
Varra
A
A
Calderoli
H
H
Jaeck
D
D
Weill-Bousson
M
M
Weill
J P
JP
D000236:Adenoma / Q000150:complications*; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000150:complications* / Q000601:surgery; D005260:Female; D006801:Humans; D007417:Intestinal Polyps / Q000150:complications*; D008875:Middle Aged; D011446:Prospective Studies; D012306:Risk; D012812:Sigmoidoscopy