title: Aerosol transmission of Hantaan and related viruses to laboratory rats.
abstract: Hantaan, Seoul, and Puumala viruses were transmitted to 12-16-week-old female Wistar Rattus norvegicus by inhalation. The rodent infectious dose for each virus by intramuscular inoculation and by inhalation was determined, as was the infectious dose for Vero E-6 cells by direct plaque assay.
authors.affiliation: Disease Assessment Division, U.S. Army Medical Research Institute of Infectious Disease, Fort Detrick, Frederick, Maryland 21701-5011.
authors.forename: E O
authors.initials: EO
authors.lastname: Nuzum
authors.forename: C A
authors.initials: CA
authors.lastname: Rossi
authors.forename: E H
authors.initials: EH
authors.lastname: Stephenson
authors.forename: J W
authors.initials: JW
authors.lastname: LeDuc
mesh_terms: D000336:Aerosols; D000391:Air Microbiology; D000818:Animals; D005260:Female; D006476:Orthohantavirus / Q000502:physiology*; D006480:Hemorrhagic Fever with Renal Syndrome / Q000635:transmission*; D051381:Rats; D014709:Vero Cells
chemical_list: D000336:Aerosols