title: Cerebrovascular autoregulation is resistant to calcium channel blockade with nimodipine.
abstract: In normal baboons cerebrovascular resistance changed along with blood pressure to maintain blood flow constant. This 'autoregulation' was not significantly altered in animals treated with a dose of the calcium channel blocker nimodipine causing selective cerebral vasodilation.
authors.affiliation: Cerebrovascular Research Laboratory, VA Medical Center, Houston, Texas.
authors.forename: T A
authors.initials: TA
authors.lastname: McCalden
authors.forename: R G
authors.initials: RG
authors.lastname: Nath
mesh_terms: D000818:Animals; D001794:Blood Pressure; D001810:Blood Volume; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D006706:Homeostasis / Q000187:drug effects*; D009553:Nimodipine / Q000494:pharmacology*; D010215:Papio; D014655:Vascular Resistance / Q000187:drug effects; D014980:Xenon Radioisotopes
chemical_list: D014980:Xenon Radioisotopes; D009553:Nimodipine