Myelodysplasia, chemical exposure, and other environmental factors.
This paper describes a case-control study of the occupational and environmental exposures of patients with myelodysplasia. The methodology, first described in Canada for solid tumors, estimates lifetime exposures to a number of potential toxic hazards or carcinogens. This pilot study confirms that the methodology, with the use of questionnaires and interviews, can estimate exposures to specific chemicals and shows some significant associations with myelodysplasia, including exposure to petrol or diesel compounds.
Farrow
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Department of Epidemiology and Community Medicine, University of Wales College of Medicine, Cardiff, U.K.
Jacobs
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West
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D000393:Air Pollutants / Q000009:adverse effects*; D000641:Ammonia / Q000009:adverse effects; D004391:Dust / Q000009:adverse effects; D005260:Female; D006801:Humans; D007509:Irritants / Q000009:adverse effects; D008297:Male; D009190:Myelodysplastic Syndromes / Q000139:chemically induced* / Q000209:etiology; D009381:Neoplasms, Radiation-Induced / Q000209:etiology; D009784:Occupational Diseases / Q000139:chemically induced* / Q000209:etiology; D010575:Pesticides / Q000009:adverse effects; D010578:Petroleum / Q000009:adverse effects; D010865:Pilot Projects; D011289:Preleukemia / Q000139:chemically induced / Q000209:etiology
D000393:Air Pollutants; D004391:Dust; D007509:Irritants; D010575:Pesticides; D010578:Petroleum; D000641:Ammonia