Rheumatoid arthritis and motor neurone disease--an association?
Three patients with rheumatoid arthritis and motor neurone disease are presented. The neurological syndrome supervened after 2, 19 and 23 years of polyarthritis and led to death within 4 years. The diagnosis of motor neurone disease was confirmed at post mortem in one case. Common immunological mechanisms may account for this previously unreported association.
Schady
W
W
University Department of Neurology, Manchester Royal Infirmary, UK.
Metcalfe
R A
RA
Holt
P J
PJ
D000328:Adult; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000503:physiopathology; D001706:Biopsy; D004576:Electromyography; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons; D009132:Muscles / Q000473:pathology / Q000503:physiopathology; D009468:Neuromuscular Diseases / Q000150:complications* / Q000503:physiopathology