Pathologic prognostic factors for cutaneous malignant melanoma: the Western Canada Melanoma Study.
An analysis of data for histopathologic factors influencing survival was conducted on 798 cases of invasive cutaneous malignant melanoma. On univariate analysis, a number of factors influenced survival; however, when these factors were examined using a proportional-hazards model, sex and log of depth of penetration were the only factors governing survival. Moreover, these factors were only important in patients with lesions up to 4 mm in depth with no evidence of other disease. For patients with solitary lesions deeper than 4 mm, or patients with regional or distant disease, none of the factors examined in our study was of predictive value for survival assessment.
Worth
A J
AJ
Cancer Control Agency of British Columbia, Vancouver, Canada.
Gallagher
R P
RP
Elwood
J M
JM
Yang
P C
PC
Lamb
C
C
Spinelli
J J
JJ
Wood
W S
WS
Threlfall
W J
WJ
Hill
G B
GB
D000328:Adult; D000367:Age Factors; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000401:mortality / Q000473:pathology*; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012737:Sex Factors; D012878:Skin Neoplasms / Q000401:mortality / Q000473:pathology*