title: Comparative biochemistry of mammalian arylsulfatases A and B.
abstract: 1. Arylsulfatases A and B occurred as a major anionic and cationic isozyme, respectively, among eleven eutherian mammalian species. 2. Minor anionic arylsulfatase B isozymes were observed in rodents, dog, whale and pig, and were either monomeric (vole, Mr = 67 +/- 2 kDa), an apparent aggregate (dog, whale, pig; Mr = 192 +/- 10 kDa), or both (rat, mouse; monomeric Mr = 57 +/- 2 kDa; apparent dimeric Mr = 114 +/- 3 kDa). 3. Minor cationic arylsulfatase A isozymes were isolated from the deer, whale and pig. 4. Opossum arylsulfatases A and B were both anionic, had similar relative molecular weights, were not inhibited by silver, and were not precipitated by anti-murine arylsulfatase B nor anti-bovine arylsulfatase A IgG preparations.
authors.affiliation: Department of Zoology, Arizona State University, Tempe 85287.
authors.forename: D B
authors.initials: DB
authors.lastname: Thompson
authors.forename: W L
authors.initials: WL
authors.lastname: Daniel
mesh_terms: D000818:Animals; D002553:Cerebroside-Sulfatase / Q000037:antagonists & inhibitors / Q000302:isolation & purification / Q000378:metabolism*; D002803:Chondro-4-Sulfatase / Q000037:antagonists & inhibitors / Q000302:isolation & purification / Q000378:metabolism*; D007700:Kinetics; D008322:Mammals / Q000378:metabolism*; D008970:Molecular Weight; D013045:Species Specificity; D013379:Substrate Specificity; D013429:Sulfatases / Q000378:metabolism*
chemical_list: D013429:Sulfatases; D002553:Cerebroside-Sulfatase; D002803:Chondro-4-Sulfatase