Lymphocyte transformation induced by autologous cells. XVII. Lower autologous mixed lymphocyte reaction in subjects with a history of hayfever.
The autologous mixed lymphocyte reaction (AMLR) is impaired in patients with a number of diseases associated with abnormal immunoregulation. Since allergic disorders are also associated with abnormal immunoregulation, we assessed the AMLR in individuals with a history of ragweed hayfever. Lymphocytes from allergic subjects had a lower AMLR than nonallergic controls by rank order analysis. These results support the association of abnormal in vivo immunoregulation with reduced AMLR.
Bovbjerg
D H
DH
Wang
V A
VA
Schwab
R
R
Lebenger
K S
KS
Siskind
G W
GW
Weksler
M E
ME
D006801:Humans; D008213:Lymphocyte Activation; D007959:Lymphocyte Culture Test, Mixed; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology*