title: A primary extraskeletal osteogenic sarcoma arising in the spleen of a dog.
abstract: This paper describes a primary extraskeletal osteogenic sarcoma arising in the spleen of an 11-year-old, male, cross-bred Terrier. Initial diagnosis was made after surgical removal of a splenic mass, at which time the liver and other abdominal viscera appeared grossly normal. However, elevations in the activities of alanine aminotransferase and alkaline phosphatase in blood taken 7 days after laparotomy suggested that hepatic metastases were developing. This was confirmed when the dog died 3.5 months after surgery, with massive hepatic metastatic involvement. There appears to be no previous report of the spleen being the primary site of such a neoplasm in the dog.
authors.affiliation: School of Veterinary Science, University of Melbourne, Parkville, Victoria.
authors.forename: A G
authors.initials: AG
authors.lastname: Jabara
authors.forename: J B
authors.initials: JB
authors.lastname: McLeod
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D008113:Liver Neoplasms / Q000097:blood / Q000556:secondary / Q000662:veterinary; D008297:Male; D012516:Osteosarcoma / Q000097:blood / Q000473:pathology / Q000556:secondary / Q000662:veterinary*; D013156:Splenectomy / Q000662:veterinary; D013160:Splenic Neoplasms / Q000473:pathology / Q000662:veterinary*