Connections of the olfactory bulb and nucleus olfactorius anterior in the hedgehog (Erinaceus europaeus): fluorescent tracers and HRP study.
The projections of the main olfactory bulbs (MOBs) and the dorsal part of the anterior olfactory nucleus (NOA) in the hedgehog (Erinaceus europaeus) have been studied by fluorescent tracers and the horseradish peroxidase method (HRP), respectively, to reveal the pattern of labeling from these structures. After different dye injections in both MOBs, labeled cells were present in the following structures: tenia tecta, vertical limb of the diagonal band of Broca, and medial septal nucleus in the ipsilateral injection site; and the NOA, piriform cortex, nucleus of the lateral olfactory tract, horizontal limb of the diagonal band of Broca, posterolateral cortical amygdaloid nucleus, anterior amygdaloid area, and dorsal raphe nucleus in both hemispheres. Structures showing double-labeled cells were the NOA, horizontal limb of the diagonal band of Broca, nucleus of the lateral olfactory tract, anterior amygdaloid area, and posterolateral cortical amygdaloid nucleus. After HRP injections in the dorsal part of the NOA, labeled cells were distributed in the NOA, nucleus of the lateral olfactory tract, posterolateral cortical amygdaloid nucleus, piriform cortex, horizontal and vertical limbs of the diagonal band of Broca, mitral cell layer of the MOB, tenia tecta, anterior amygdaloid area, and the contralateral NOA. We suggest that the contralateral projection nuclei to the MOB of the hedgehog, unusual in other mammals, and the large number of cells with axonal collaterals projecting to both hemispheres, may be a strategy in these animals to bilaterally integrate brain functions at the expense of its reduced corpus callosum.
De Carlos
J A
JA
Laboratorio de Neuroanatomía Comparada, Instituto de Neurobiología, Santiago Ramón y Cajal, CSIC, Madrid, Spain.
López-Mascaraque
L
L
Valverde
F
F
D000818:Animals; D001931:Brain Mapping; D002490:Central Nervous System / Q000033:anatomy & histology*; D005260:Female; D005456:Fluorescent Dyes; D006364:Hedgehogs / Q000033:anatomy & histology*; D006735:Horseradish Peroxidase; D008297:Male; D009830:Olfactory Bulb / Q000033:anatomy & histology* / Q000166:cytology; D009833:Olfactory Pathways / Q000033:anatomy & histology* / Q000166:cytology
D005456:Fluorescent Dyes; D006735:Horseradish Peroxidase