Mechanism of regulation of calcium concentration by platelet membranes.
Calcium is recognised as an important messenger in the platelet activation. Both the external and internal membranes are considered to play an important role in the Ca2+ homeostasis of the cell. The aim of this review is to try to understand the mechanisms of regulation of the cytoplasmic free Ca2+ concentration by both kinds of membranes and mainly by internal membranes.
Levy-Toledano
S
S
Enouf
J
J
Bredoux
R
R
de Metz
M
M
Lebret
M
M
D001693:Biological Transport, Active; D001792:Blood Platelets / Q000378:metabolism*; D017301:Ca(2+) Mg(2+)-ATPase / Q000097:blood; D002118:Calcium / Q000097:blood*; D000252:Calcium-Transporting ATPases / Q000097:blood; D002462:Cell Membrane / Q000378:metabolism; D006023:Glycoproteins / Q000302:isolation & purification; D006706:Homeostasis; D006801:Humans; D007700:Kinetics; D008565:Membrane Proteins / Q000302:isolation & purification; D008954:Models, Biological; D008970:Molecular Weight; D010766:Phosphorylation; D010974:Platelet Aggregation; D010980:Platelet Membrane Glycoproteins
D006023:Glycoproteins; D008565:Membrane Proteins; D010980:Platelet Membrane Glycoproteins; D017301:Ca(2+) Mg(2+)-ATPase; D000252:Calcium-Transporting ATPases; D002118:Calcium