Superficial granulomatous pyoderma: clinicopathologic spectrum.
Superficial granulomatous pyoderma is a form of pyoderma gangrenosum characterized by superficial ulceration and a chronic course. Histopathologic examination shows a granulomatous response. We report two new cases of superficial granulomatous pyoderma in detail and briefly review the clinical data of five previous cases included in a recent series. These lesions typically begin as single furunculoid papules that most commonly occur on the trunk and that may arise at sites of surgical treatment or other pathergic stimuli. The lesions progress to superficial ulcers with a relatively clean base and vegetative borders. Tetracycline, minocycline, sulfapyridine, dapsone, and intralesionally administered corticosteroids have been effective anti-inflammatory agents, producing healing and allowing avoidance of the use of systemic corticosteroids in the management of most patients with superficial granulomatous pyoderma.
Quimby
S R
SR
Department of Dermatology, Mayo Clinic Scottsdale, AZ 85259.
Gibson
L E
LE
Winkelmann
R K
RK
D000328:Adult; D000368:Aged; D005500:Follow-Up Studies; D006099:Granuloma / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011711:Pyoderma / Q000150:complications* / Q000188:drug therapy / Q000473:pathology