Pseudocholinesterase in obsessive-compulsive patients.
Levels of pseudocholinesterase (PsChe) were measured in 20 patients with obsessive-compulsive disorder (OCD) and 20 healthy volunteers. The OCD group had significantly higher PsChe serum activity than in their sex- and age-matched control group. Patients' scores on the Hamilton Rating Scale for Anxiety (HRS-A) and the Beck Depression Inventory (BDI) were not correlated with their PsChe levels. The results provide additional support for the observation of higher PsChe levels among anxiety-related psychiatric conditions. However, the relationships among anxiety, depression, and PsChe appear to be complex. The nature and implications of elevated PsChe levels are still unknown.
Aizenberg
D
D
Gehah Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva, Israel.
Hermesh
H
H
Karp
L
L
Munitz
H
H
D000328:Adult; D001008:Anxiety Disorders / Q000201:enzymology; D002091:Butyrylcholinesterase / Q000097:blood*; D002802:Cholinesterases / Q000097:blood*; D003866:Depressive Disorder / Q000201:enzymology; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000201:enzymology*; D011581:Psychological Tests; D012008:Recurrence
D002091:Butyrylcholinesterase; D002802:Cholinesterases