title: Mechanism of regulation of calcium concentration by platelet membranes.
abstract: Calcium is recognised as an important messenger in the platelet activation. Both the external and internal membranes are considered to play an important role in the Ca2+ homeostasis of the cell. The aim of this review is to try to understand the mechanisms of regulation of the cytoplasmic free Ca2+ concentration by both kinds of membranes and mainly by internal membranes.
authors.forename: S
authors.initials: S
authors.lastname: Levy-Toledano
authors.forename: J
authors.initials: J
authors.lastname: Enouf
authors.forename: R
authors.initials: R
authors.lastname: Bredoux
authors.forename: M
authors.initials: M
authors.lastname: de Metz
authors.forename: M
authors.initials: M
authors.lastname: Lebret
mesh_terms: D001693:Biological Transport, Active; D001792:Blood Platelets / Q000378:metabolism*; D017301:Ca(2+) Mg(2+)-ATPase / Q000097:blood; D002118:Calcium / Q000097:blood*; D000252:Calcium-Transporting ATPases / Q000097:blood; D002462:Cell Membrane / Q000378:metabolism; D006023:Glycoproteins / Q000302:isolation & purification; D006706:Homeostasis; D006801:Humans; D007700:Kinetics; D008565:Membrane Proteins / Q000302:isolation & purification; D008954:Models, Biological; D008970:Molecular Weight; D010766:Phosphorylation; D010974:Platelet Aggregation; D010980:Platelet Membrane Glycoproteins
chemical_list: D006023:Glycoproteins; D008565:Membrane Proteins; D010980:Platelet Membrane Glycoproteins; D017301:Ca(2+) Mg(2+)-ATPase; D000252:Calcium-Transporting ATPases; D002118:Calcium