title: Linkage analysis of the Duffy blood group marker with several chromosome 1 genes in an extended pedigree with Charcot-Marie-Tooth disease.
abstract: We have recently demonstrated tight linkage of the Duffy blood group marker to the alpha-spectrin gene in an extended pedigree with Charcot-Marie-Tooth neuropathy. To determine a more precise location of the Duffy blood group locus on the chromosome 1 map we have tested several more chromosome 1 genes for linkage with this marker. We found suggestive linkage with the antithrombin III and apolipoprotein A2 genes and conclusive linkage with the gene coding for beta-nerve growth factor.
authors.affiliation: Department of Biochemistry, University of Antwerpen, Belgium.
authors.forename: P
authors.initials: P
authors.lastname: Raeymaekers
authors.forename: C
authors.initials: C
authors.lastname: Van Broeckhoven
authors.forename: H
authors.initials: H
authors.lastname: Backhovens
authors.forename: A
authors.initials: A
authors.lastname: Wehnert
authors.forename: L
authors.initials: L
authors.lastname: Muylle
authors.forename: P
authors.initials: P
authors.lastname: De Jonghe
authors.forename: J
authors.initials: J
authors.lastname: Gheuens
authors.forename: J J
authors.initials: JJ
authors.lastname: Martin
authors.forename: A
authors.initials: A
authors.lastname: Vandenberghe
mesh_terms: D001789:Blood Group Antigens / Q000235:genetics*; D002607:Charcot-Marie-Tooth Disease / Q000235:genetics*; D002871:Chromosome Banding; D002878:Chromosomes, Human, Pair 1; D004375:Duffy Blood-Group System / Q000235:genetics*; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D009134:Muscular Atrophy, Spinal / Q000235:genetics*
chemical_list: D001789:Blood Group Antigens; D004375:Duffy Blood-Group System; D005819:Genetic Markers