Orientation of alpha-helical peptides in a lipid bilayer.
Samples of pure lipid (dipalmitoylphosphatidylcholine) and lipid containing short alpha-helical peptides were oriented and examined by X-ray diffraction, together with unoriented samples of pure peptide. X-ray reflections from the bilayer and the alpha-helices showed that the peptides had oriented in the bilayer with their helical axes perpendicular to the surface.
Huschilt
J C
JC
Physics Department, University of Guelph, Canada.
Millman
B M
BM
Davis
J H
JH
D015060:1,2-Dipalmitoylphosphatidylcholine; D006860:Hydrogen Bonding; D066298:In Vitro Techniques; D008051:Lipid Bilayers; D008565:Membrane Proteins / Q000648:ultrastructure*; D009842:Oligopeptides / Q000138:chemical synthesis; D014961:X-Ray Diffraction
D008051:Lipid Bilayers; D008565:Membrane Proteins; D009842:Oligopeptides; D015060:1,2-Dipalmitoylphosphatidylcholine