title: Pulmonary alveolar proteinosis. Occurrence with metastatic melanoma to lung.
abstract: Pulmonary alveolar proteinosis is characterized by excessive accumulation of surfactant-like material in the alveoli, resulting in part from defective alveolar clearance by macrophages. We present a case of alveolar proteinosis in a patient with malignant melanoma metastatic to lung and discuss possible alteration in macrophage function in the pathogenesis of these two concomitant processes.
authors.affiliation: Department of Radiological Sciences, University of California Los Angeles School of Medicine.
authors.forename: V
authors.initials: V
authors.lastname: Schiller
authors.forename: D R
authors.initials: DR
authors.lastname: Aberle
authors.forename: A M
authors.initials: AM
authors.lastname: Aberle
mesh_terms: D000328:Adult; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000556:secondary*; D008297:Male; D008545:Melanoma / Q000150:complications / Q000556:secondary*; D011649:Pulmonary Alveolar Proteinosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography