title: A steady state method of measuring carbon monoxide diffusing capacity of the lung of sheep.
abstract: A method for measuring the diffusing capacity of the lung for carbon monoxide (DLCO) in sheep was developed. The test's usefulness and reliability was studied in ten, splenectomized adult ewes. Hemoglobin concentration and weight were found to affect sheep DLCO. This article describes a method of determining DLCO in sheep, gives preliminary results of limited testing, and discusses factors affecting DLCO in sheep.
authors.affiliation: Department of Respiratory Research, Walter Reed Army Institute of Research, Washington, DC 20307-5100.
authors.forename: J S
authors.initials: JS
authors.lastname: McNeil
authors.forename: K G
authors.initials: KG
authors.lastname: Torrington
authors.forename: T G
authors.initials: TG
authors.lastname: Mundie
authors.forename: G R
authors.initials: GR
authors.lastname: Ripple
authors.forename: Y Y
authors.initials: YY
authors.lastname: Phillips
mesh_terms: D000818:Animals; D001835:Body Weight; D002248:Carbon Monoxide / Q000032:analysis* / Q000378:metabolism; D004058:Diffusion; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D008168:Lung / Q000502:physiology*; D012756:Sheep / Q000502:physiology*; D013156:Splenectomy
chemical_list: D006454:Hemoglobins; D002248:Carbon Monoxide