Photodynamic therapy with haematoporphyrin derivative on mice with solid Ehrlich carcinomas.
The tumor-toxic effect of the photosensitizer HpD/Halle activated by laser radiation was demonstrated. Solid Ehrlich carcinoma was used as model. Investigations into the tumor growth, the HpD-distribution after different kinds of drug administration by means of fluorescence measurements, the phototoxicity and the reduction of tumor masses after HpD application and laser irradiation were carried out.
König
K
K
Department of Physics, Friedrich-Schiller University Jena, GDR.
Bockhorn
V
V
Krause
U
U
Dietel
W
W
Schubert
H
H
Lotz
P
P
Löbe
L P
LP
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy*; D005260:Female; D006414:Hematoporphyrin Photoradiation; D008297:Male; D009368:Neoplasm Transplantation; D010778:Photochemotherapy