[Somatostatin does not modify 3-oxymethylglucose and leucine uptake by rat enterocytes].
The effects of somatostatin on 3-oxymethylglucose (3-OMG) and leucine uptake by rat enterocytes were examined. Somatostatin did not decrease the 3-OMG enterocyte uptake. When the 3-OMG active transport was inhibited by phloridzin, Somatostatin presented no significant modifications. Somatostatin showed a slight decrease in 3-OMG release through the basolateral membrane, when such a release was inhibited with theophylline. Somatostatin did not modify the intestinal leucine uptake or its inhibition by methionine.
Crespo
C A
CA
Departamento de Fisiología Facultad de Farmacia, Santiago de Compostela, España.
Martínez-Sapiña
J
J
Taboada
M C
MC
D019325:3-O-Methylglucose; D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D005260:Female; D007413:Intestinal Mucosa / Q000378:metabolism*; D007422:Intestines / Q000187:drug effects; D007930:Leucine / Q000493:pharmacokinetics*; D008297:Male; D008757:Methylglucosides / Q000493:pharmacokinetics*; D008759:Methylglycosides / Q000493:pharmacokinetics*; D051381:Rats; D011919:Rats, Inbred Strains; D013004:Somatostatin / Q000494:pharmacology*
D008757:Methylglucosides; D008759:Methylglycosides; D019325:3-O-Methylglucose; D013004:Somatostatin; D007930:Leucine
La somatostatina no modifica la captación de 3-oximetilglucosa y leucina por enterocitos de rata.