[Effect of L-thyroxine on skeletal muscle fibers of the frog].
L-thyroxin prevents neither the postdenervation decrease of resting MP, nor the increase of input resistance, nor the extrajunctional sensitivity to acetylcholine, but after the injection the cross-sectional areas of muscle fibers decrease more rapidly than after a mere denervation and muscle fibers of new type by myosin-ATPase activity do not appear. The same doses of hormone do not affect properties of muscle fiber membrane but increase the input resistance of membrane and decrease cross-sectional areas of muscle fibers. l-thyroxin seems unable to prevent the appearance of the postdenervation changes in skeletal muscle fibers in adult frog and does not take part in regulation of its differentiation.
Volkov
E M
EM
Valiullin
V V
VV
D000109:Acetylcholine / Q000494:pharmacology; D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D004347:Drug Interactions; D004553:Electric Conductivity; D008564:Membrane Potentials / Q000187:drug effects; D009121:Muscle Denervation; D009132:Muscles / Q000187:drug effects* / Q000378:metabolism; D011895:Rana ridibunda; D013974:Thyroxine / Q000494:pharmacology*
D000251:Adenosine Triphosphatases; D000109:Acetylcholine; D013974:Thyroxine
Vliianie L-tiroksina na skeletnye myshechnye volokna liagushki.