Antibiotic resistance of coagulase-negative staphylococci in an orthopaedic department.
Coagulase-negative staphylococci (CNS) were cultured from the anterior nares of surgeons, theatre and ward staff, and from patients before and 2 weeks after a total hip replacement. The CNS found in ward staff were more resistant to antibiotics than those in surgeons and theatre staff. Methicillin resistance of CNS in patients increased from 4 to 31% following surgery. Gentamicin-resistant CNS were only found postoperatively, in 20% of patients, in most of whom gentamicin-loaded acrylic bone cement was used.
Sanzén
L
L
Department of Orthopaedics, University of Lund, Malmö General Hospital, Sweden.
Walder
M
M
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003030:Coagulase / Q000378:metabolism; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D006801:Humans; D007595:Joint Prosthesis; D009666:Nose / Q000382:microbiology; D009985:Orthopedics; D010564:Personnel, Hospital; D011183:Postoperative Complications / Q000453:epidemiology / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology*; D013210:Staphylococcus / Q000201:enzymology; D013503:Surgery Department, Hospital
D000900:Anti-Bacterial Agents; D003030:Coagulase