Hydrogenation of quinone compounds during secondary ion mass spectra measurement.
Antibiotics containing a quinone group show characteristic reduced pseudo-molecular ions (M + 2)+ and (M + 3)+ during the measurements of secondary ion mass spectra using glycerol as a matrix. The ratios of peak intensities (M + 2)+ and (M + 3)+ over (M + 1)+ increase with time. As this phenomenon is not found using sulfolane as a matrix, the quinone group seems to be hydrogenated to a hydroquinone by active hydrogen which is produced from a free hydroxyl group of the glycerol by bombardment with the Xe+ beam. This hydrogenation reaction is specific for the quinone group.
Ishihara
Y
Y
Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Japan.
Shirahata
K
K
Sano
H
H
D000900:Anti-Bacterial Agents; D013058:Mass Spectrometry; D011809:Quinones
D000900:Anti-Bacterial Agents; D011809:Quinones