title: Hydrogenation of quinone compounds during secondary ion mass spectra measurement.
abstract: Antibiotics containing a quinone group show characteristic reduced pseudo-molecular ions (M + 2)+ and (M + 3)+ during the measurements of secondary ion mass spectra using glycerol as a matrix. The ratios of peak intensities (M + 2)+ and (M + 3)+ over (M + 1)+ increase with time. As this phenomenon is not found using sulfolane as a matrix, the quinone group seems to be hydrogenated to a hydroquinone by active hydrogen which is produced from a free hydroxyl group of the glycerol by bombardment with the Xe+ beam. This hydrogenation reaction is specific for the quinone group.
authors.affiliation: Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Ishihara
authors.forename: K
authors.initials: K
authors.lastname: Shirahata
authors.forename: H
authors.initials: H
authors.lastname: Sano
mesh_terms: D000900:Anti-Bacterial Agents; D013058:Mass Spectrometry; D011809:Quinones
chemical_list: D000900:Anti-Bacterial Agents; D011809:Quinones