title: The development of encapsulated filtering blebs.
abstract: The development of an encapsulated filtering bleb (Tenon's cyst) complicated 56 of 409 consecutive filtering operations (13.7%) performed during a 40-month period after January 1983. Fifteen eyes (27.8% of encapsulated blebs) required surgical revision. The recognition of bleb encapsulation occurred 20.4 +/- 12.7 days (mean +/- standard deviation) postoperatively. Prolonged duration of beta-adrenergic antagonist therapy was associated with an increased frequency of bleb encapsulation (180.6 +/- 128.5 weeks without encapsulation, 229.0 +/- 129.3 weeks with encapsulation, P less than 0.009). Bleb encapsulation occurred in 42 of 272 eyes with previous argon laser trabeculoplasty, but in only 4 of 85 eyes without any previous anterior segment laser (P less than 0.01). Encapsulated filtering blebs developed in 4 of 12 (33.3%) eyes with congenital glaucoma and 4 of 9 (44.4%) eyes with juvenile glaucoma (P less than 0.0002). The intraocular pressures (IOPs) in the eyes with encapsulated filtering blebs were significantly elevated at 1, 2, and 3 postoperative weeks, and at final follow-up compared with eyes without bleb encapsulation.
authors.affiliation: Glaucoma Service, Ophthalmic Consultants of Boston, Inc, MA 02114.
authors.forename: C U
authors.initials: CU
authors.lastname: Richter
authors.forename: B J
authors.initials: BJ
authors.lastname: Shingleton
authors.forename: A R
authors.initials: AR
authors.lastname: Bellows
authors.forename: B T
authors.initials: BT
authors.lastname: Hutchinson
authors.forename: T
authors.initials: T
authors.lastname: O'Connor
authors.forename: I
authors.initials: I
authors.lastname: Brill
mesh_terms: D000293:Adolescent; D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003229:Conjunctival Diseases / Q000209:etiology*; D005374:Filtration; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D007223:Infant; D007429:Intraocular Pressure; D053685:Laser Therapy; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology*; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D000319:Adrenergic beta-Antagonists