Presence of pancreatic-type phospholipase A2 mRNA in rat gastric mucosa and lung.
The content of mRNA for a pancreatic-type phospholipase A2 present in rat gastric mucosa was much greater than that in pancreas. In lung the mRNA for this pancreatic-type phospholipase A2 was also detected, but less than in pancreas. Nucleotide sequence analysis showed that these pancreatic-type phospholipase A2 cDNAs derived from rat gastric mucosa and lung were completely identical to that from rat pancreas (Ohara et al. (1986) J. Biochem. 99, 733-739). This demonstrates that the pancreatic-type phospholipase A2 present in gastric mucosa and lung does not originate from pancreas.
Sakata
T
T
Shionogi Research Laboratories, Shionogi & Co., Ltd., Osaka, Japan.
Nakamura
E
E
Tsuruta
Y
Y
Tamaki
M
M
Teraoka
H
H
Tojo
H
H
Ono
T
T
Okamoto
M
M
D000818:Animals; D001483:Base Sequence; D015152:Blotting, Northern; D003001:Cloning, Molecular; D004247:DNA; D015342:DNA Probes; D005753:Gastric Mucosa / Q000032:analysis*; D008168:Lung / Q000032:analysis*; D008969:Molecular Sequence Data; D010740:Phospholipases / Q000032:analysis*; D010741:Phospholipases A / Q000032:analysis* / Q000235:genetics / Q000502:physiology; D054467:Phospholipases A2; D012333:RNA, Messenger / Q000032:analysis*; D051381:Rats
D015342:DNA Probes; D012333:RNA, Messenger; D004247:DNA; D010740:Phospholipases; D010741:Phospholipases A; D054467:Phospholipases A2