[A case of remission of metastatic gastric cancer lesions in the chest and abdominal wall by 5'-DFUR administration].
52-year-old female was weakened and bed-ridden by metastasis of gastric cancer to the chest and abdominal wall, and peritonitis carcinomatosa 2 years after gastrectomy. One week after administration of 5'-DFUR, 1200 mg/d, p.o., a clinical effect was seen. In 3 weeks metastatic lesions had diminished in size, ascites had decreased and the patient had regained her appetite and put on weight. She recovered sufficiently to be able to do some daily work. Pathological degeneration and necrosis of cancer cells were observed. Although she died 8 months after remission, 5'-DFUR was effective in improving her condition and prolonging her life.
Komuro
K
K
Mitsumori
N
N
Iwamoto
K
K
Murai
R
R
Ishida
T
T
Nagasaki
Y
Y
Hujii
Y
Y
Amano
R
R
Yamazaki
M
M
Nagayama
A
A
D000009:Abdominal Muscles; D000230:Adenocarcinoma / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary; D000284:Administration, Oral; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005260:Female; D005467:Floxuridine / Q000627:therapeutic use*; D005743:Gastrectomy; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009336:Necrosis; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery; D013909:Thorax
D000970:Antineoplastic Agents; D005467:Floxuridine; C025034:doxifluridine