[Acute myelomonocytic leukemia with eosinophils. Apropos of a case with a cytogenetic analysis and nosologic discussion].
Report of overwhelming leukemia with meningeal involvement in a 13-year-old. Cytologic and ultrastructural examinations showed features of myelomonocytic leukemia with abnormal eosinophils. The karyotype showed pericentric inversion of chromosome 16. Although these findings establish the diagnosis of acute myelomonocytic leukemia with abnormal eosinophils (M4Eo), this case ran an exceptionally severe course and exhibited some unusual cytologic features.
Battin
J
J
Guérin-Darmendrail
V
V
Martin
V
V
D000293:Adolescent; D001853:Bone Marrow / Q000473:pathology; D002869:Chromosome Aberrations / Q000473:pathology*; D025063:Chromosome Disorders; D002885:Chromosomes, Human, Pair 16; D004804:Eosinophils / Q000473:pathology; D006098:Granulocytes / Q000473:pathology; D006801:Humans; D015479:Leukemia, Myelomonocytic, Acute / Q000145:classification / Q000235:genetics / Q000473:pathology*; D008297:Male
Leucémie aiguë myélomonocytaire avec éosinophiles. A propos d'un cas avec étude cytogénétique et discussion nosologique.