[Decrease in the blood toxicity of antitumor preparations during enterosorption].
It is shown that peroral administration of activated charcoal SCN in rats with subcutaneously grafted Guerin carcinoma and Svec erythroleucosis does not hamper the antitumoural action of cyclophosphamide, methotrexate, and carminomycin and provides a protective effect on the medullar haemopoiesis.
Bonatskaia
L V
LV
Plotnikov
V M
VM
Nikolaev
V G
VG
D000327:Adsorption; D000818:Animals; D001769:Blood / Q000187:drug effects*; D002277:Carcinoma / Q000097:blood / Q000188:drug therapy; D002360:Carubicin / Q000633:toxicity*; D002606:Charcoal / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000633:toxicity*; D003630:Daunorubicin / Q000031:analogs & derivatives*; D006410:Hematopoiesis / Q000187:drug effects; D007408:Intestinal Absorption / Q000187:drug effects*; D004915:Leukemia, Erythroblastic, Acute / Q000097:blood / Q000188:drug therapy; D008727:Methotrexate / Q000633:toxicity*; D009368:Neoplasm Transplantation; D051381:Rats
D002606:Charcoal; D003520:Cyclophosphamide; D002360:Carubicin; D008727:Methotrexate; D003630:Daunorubicin
Snizhenie gematotoksichnosti protivoopukholevykh preparatov pri énterosorbtsii.