title: Activation of mouse peritoneal macrophages by mannophosphoinositides of mycobacteria.
abstract: Peritoneal macrophages isolated from mannoside-methylated bovine serum albumin (MBSA)-immunized mice showed significantly enhanced phagocytosis of Mycobacterium smegmatis compared to control or MBSA-immunized groups. Immune macrophages also exhibited bacteriostatic activity against M. smegmatis. Pretreatment of mycobacteria with mannoside antibodies did not further alter the phagocytosis and bacteriostatic effect of immune macrophages.
authors.affiliation: Department of Biochemistry, Postgraduate Institute of Medical Education and Research, Changigarh, India.
authors.forename: P K
authors.initials: PK
authors.lastname: Mehta
authors.forename: G K
authors.initials: GK
authors.lastname: Khuller
mesh_terms: D000818:Animals; D006027:Glycosides / Q000276:immunology*; D007114:Immunization; D008262:Macrophage Activation; D008362:Mannosides / Q000276:immunology*; D051379:Mice; D008815:Mice, Inbred Strains; D009161:Mycobacterium / Q000276:immunology*; D010529:Peritoneal Cavity / Q000166:cytology; D010587:Phagocytosis; D012710:Serum Albumin, Bovine / Q000276:immunology
chemical_list: D006027:Glycosides; D008362:Mannosides; D012710:Serum Albumin, Bovine