Congenital complete heart block in an infant with free plasma carnitine deficiency.
A newborn male presenting with congenital complete heart block was found to have low levels of free plasma carnitine. Among the many complications of carnitine deficiency is a structural disruption of myocardial tissue. A deficiency of carnitine may be causally related to the presence of cardiac dysrhythmias in this patient on the basis of mechanical disturbance to the cardiac conducting system.
Erasmus
M J
MJ
Department of Pediatrics, University Hospital, Saskatoon, Saskatchewan.
Duncan
W J
WJ
Tyrrell
M J
MJ
D000138:Acidosis / Q000209:etiology; D002331:Carnitine / Q000172:deficiency*; D006327:Heart Block / Q000151:congenital* / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009206:Myocardium / Q000648:ultrastructure; D010138:Pacemaker, Artificial
D002331:Carnitine