title: Pathologic prognostic factors for cutaneous malignant melanoma: the Western Canada Melanoma Study.
abstract: An analysis of data for histopathologic factors influencing survival was conducted on 798 cases of invasive cutaneous malignant melanoma. On univariate analysis, a number of factors influenced survival; however, when these factors were examined using a proportional-hazards model, sex and log of depth of penetration were the only factors governing survival. Moreover, these factors were only important in patients with lesions up to 4 mm in depth with no evidence of other disease. For patients with solitary lesions deeper than 4 mm, or patients with regional or distant disease, none of the factors examined in our study was of predictive value for survival assessment.
authors.affiliation: Cancer Control Agency of British Columbia, Vancouver, Canada.
authors.forename: A J
authors.initials: AJ
authors.lastname: Worth
authors.forename: R P
authors.initials: RP
authors.lastname: Gallagher
authors.forename: J M
authors.initials: JM
authors.lastname: Elwood
authors.forename: P C
authors.initials: PC
authors.lastname: Yang
authors.forename: C
authors.initials: C
authors.lastname: Lamb
authors.forename: J J
authors.initials: JJ
authors.lastname: Spinelli
authors.forename: W S
authors.initials: WS
authors.lastname: Wood
authors.forename: W J
authors.initials: WJ
authors.lastname: Threlfall
authors.forename: G B
authors.initials: GB
authors.lastname: Hill
mesh_terms: D000328:Adult; D000367:Age Factors; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000401:mortality / Q000473:pathology*; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012737:Sex Factors; D012878:Skin Neoplasms / Q000401:mortality / Q000473:pathology*