title: Homogentisic acid determined in biological fluids by HPLC.
abstract: In this rapid, specific, and sensitive high-performance liquid-chromatographic method of analysis for homogentisic acid in biological fluids, homogentisic acid is separated on a column of Nucleosil CN. This method, which we applied to the diagnosis of three cases of alcaptonuria, represents a suitable analytical tool for the diagnosis of alcaptonuria.
authors.affiliation: Lab. de Biochimie, Hôpital Debrousse, Lyon, France.
authors.forename: C
authors.initials: C
authors.lastname: Bory
authors.forename: R
authors.initials: R
authors.lastname: Boulieu
authors.forename: C
authors.initials: C
authors.lastname: Chantin
authors.forename: M
authors.initials: M
authors.lastname: Mathieu
mesh_terms: D000328:Adult; D000474:Alkaptonuria / Q000175:diagnosis; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006713:Homogentisic Acid / Q000032:analysis* / Q000097:blood / Q000652:urine; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D006713:Homogentisic Acid