title: Ultrastructure of the APUD-like cells of the frog thymus gland.
abstract: Within the thymus gland of the European common frog, Rana temporaria, cells with endocrine- like appearance have been found. At the ultrastructural level the most characteristic feature of their cytoplasm is the presence of secretory granules. Some cells possess irregular electron lucent granules with an eccentrically located dense core while others possess smaller electron dense granules. The cytoplasm contains also cisterns of rough endoplasmic reticulum, free ribosomes, and small mitochondria. The cells possess irregular nuclei with the pronounced nucleoli. These endocrine-like cells are connected by desmosomes with neighbouring non-granulated epithelial cells. Ultrastructural features of the cells described here resemble those seen in polypeptide hormone-secreting cells belonging to the family of cells of the APUD (Amine Precursor Uptake and Decarboxylation) series.
authors.affiliation: Laboratory of Electron Microscopy, Academy of Agriculture, Kraków, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Bigaj
authors.forename: B
authors.initials: B
authors.lastname: PŁytycz
mesh_terms: D001078:APUD Cells / Q000648:ultrastructure*; D000818:Animals; D011896:Rana temporaria; D012621:Seasons; D013950:Thymus Gland / Q000648:ultrastructure*