title: [Animal models of tardive dyskinesia].
abstract: It is possible to induce in monkeys abnormal movements of the mouth and tongue resembling strikingly tardive dyskinesia. Such movements can be induced by chronic treatment with neuroleptics or by lesions placed in the habenular interpeduncular tract or nucleus parafascicularis thalami. Dopaminergic D1 and D2 receptors are involved in the modulation of such movements.
authors.affiliation: Département d'Anatomie, Faculté de Médecine, Université Laval, Québec, Canada.
authors.forename: P J
authors.initials: PJ
authors.lastname: Bédard
authors.forename: R
authors.initials: R
authors.lastname: Boucher
authors.forename: T
authors.initials: T
authors.lastname: DiPaolo
mesh_terms: D000818:Animals; D014150:Antipsychotic Agents / Q000633:toxicity; D004195:Disease Models, Animal; D004409:Dyskinesia, Drug-Induced / Q000209:etiology*; D006801:Humans; D008252:Macaca fascicularis; D008253:Macaca mulatta; D008875:Middle Aged; D051381:Rats; D013787:Thalamic Nuclei / Q000502:physiology
chemical_list: D014150:Antipsychotic Agents
vernacular_title: Les modèles animaux de la dyskinésie tardive.