Quantitative analysis of intermediate phosphate-oxygen exchange during hydrolyses by ATPases.
A simple mathematical model is presented that predicts the paradoxical effect of substrate concentration on the extent of oxygen exchange into the phosphate produced during hydrolyses of nucleotide triphosphates by ATPases in labelled water. The same model also predicts the deviations from Michaelis-Menten kinetics observed at low salt concentrations.
Jenkins
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WT
D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000255:Adenosine Triphosphate / Q000378:metabolism; D002736:Chloroplasts / Q000201:enzymology; D006160:Guanosine Triphosphate / Q000378:metabolism; D006868:Hydrolysis; D007293:Inosine Triphosphate / Q000378:metabolism; D007700:Kinetics; D008433:Mathematics; D010100:Oxygen / Q000378:metabolism*; D010710:Phosphates / Q000378:metabolism*; D010944:Plants / Q000201:enzymology
D010710:Phosphates; D007293:Inosine Triphosphate; D006160:Guanosine Triphosphate; D000255:Adenosine Triphosphate; D000251:Adenosine Triphosphatases; D010100:Oxygen