title: Differences in prognostic factors between leukemia and lymphoma type of adult T-cell leukemia.
abstract: Prognostic factors affecting the survival of adult T-cell leukemia (ATL) patients were analyzed in three groups: total cases, leukemia type cases, and lymphoma type cases. Factors found to be important overall, i.e. for total cases, were leukocyte count, ATL cell ratio in the peripheral blood, serum calcium levels and lactate dehydrogenase (LDH) level. Of those, LDH level proved not significant when evaluated separately for leukemia type or lymphoma type cases. Leukocyte count and ATL cell ratio were significant in leukemia type patients, whereas it was serum calcium level that was significant in lymphoma type; there were mutually exclusive sets of factors for the two groups. Thus, prognostic factors for ATL patients should be considered separately for each type of the disease.
authors.affiliation: Department of Internal Medicine, Saga Medical School, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Shimamoto
authors.forename: K
authors.initials: K
authors.lastname: Ono
authors.forename: M
authors.initials: M
authors.lastname: Sano
authors.forename: M
authors.initials: M
authors.lastname: Matsuzaki
authors.forename: K
authors.initials: K
authors.lastname: Suga
authors.forename: E
authors.initials: E
authors.lastname: Sueoka
authors.forename: T
authors.initials: T
authors.lastname: Tokioka
authors.forename: M
authors.initials: M
authors.lastname: Yamaguchi
authors.forename: H
authors.initials: H
authors.lastname: Suzuki
authors.forename: H
authors.initials: H
authors.lastname: Sato
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002118:Calcium / Q000097:blood; D005260:Female; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D015458:Leukemia, T-Cell / Q000097:blood / Q000401:mortality*; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000097:blood / Q000401:mortality*; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D011379:Prognosis
chemical_list: D007770:L-Lactate Dehydrogenase; D002118:Calcium