title: Micropenis and congenital adrenal hypoplasia.
abstract: Micropenis is often an early sign of congenital hypopituitarism. It has also been associated with congenital adrenal hypoplasia in infants with anencephaly and pituitary agenesis. This report is on two infants with micropenis and congenital adrenal hypoplasia. One presented with a similar clinical course and postmortem findings to previously reported cases of adrenal hypoplasia and pituitary agenesis. The other patient represents the first reported case of an infant with micropenis and congenital adrenal hypoplasia in the absence of pituitary agenesis. The histologic patterns of adrenal hypoplasia, as well as the etiologic and clinical implications of its association with micropenis, are discussed.
authors.affiliation: Department of Pediatrics, Texas Tech University Health Sciences Center, Lubbock 79430.
authors.forename: M J
authors.initials: MJ
authors.lastname: Bourgeois
authors.forename: B
authors.initials: B
authors.lastname: Jones
authors.forename: D C
authors.initials: DC
authors.lastname: Waagner
authors.forename: D
authors.initials: D
authors.lastname: Dunn
mesh_terms: D000311:Adrenal Glands / Q000002:abnormalities*; D000309:Adrenal Insufficiency / Q000151:congenital*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010413:Penis / Q000002:abnormalities*; D010903:Pituitary Gland, Anterior / Q000002:abnormalities*