title: T-cell lymphoma mimicking granulocytic sarcoma.
abstract: A case of diffuse large cell lymphoma is described in which eosinophils and eosinophilic myelocytes were admixed with the neoplastic lymphoid cells. Because of the eosinophilic myelocytes, a diagnosis of granulocytic sarcoma was initially considered. No abnormalities of peripheral blood or bone marrow were found. Immunohistochemical studies of lymph node tissue demonstrated membrane antigens consistent with a lymphoma of helper T-cells. Small lymphoid cells with markedly irregular nuclei were present but rather inconspicuous among the larger lymphoid cells. Although a clinical remission was attained, the patient had a relapse with central nervous system involvement.
authors.forename: C C
authors.initials: CC
authors.lastname: Whitcomb
authors.forename: W L
authors.initials: WL
authors.lastname: Sternheim
authors.forename: M J
authors.initials: MJ
authors.lastname: Borowitz
authors.forename: E
authors.initials: E
authors.lastname: Davila
authors.forename: G E
authors.initials: GE
authors.lastname: Byrne
mesh_terms: D000911:Antibodies, Monoclonal; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D003937:Diagnosis, Differential; D004804:Eosinophils / Q000473:pathology*; D006801:Humans; D007951:Leukemia, Myeloid / Q000175:diagnosis* / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008223:Lymphoma / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology / Q000473:pathology
chemical_list: D000911:Antibodies, Monoclonal