title: Recurrent bacterial meningitis. Secondary to malformation of the inner ear.
abstract: A 5-year-old girl with congenital sensorial deafness experienced four episodes of bacterial meningitis in a 13-month period. On the fourth episode, an extensive search for the cause of recurrent meningitis was conducted. Complete immunologic studies, humoral, cellular, and phagocytic, yielded negative results. Precise otological examination, i.e., skull roentgenograms, an inner ear target CT scan, and puncture of the eardrum, was attempted, which disclosed the inner ear malformation (Mondini's anomaly) and a cerebrospinal fluid (CSF) fistula. CSF discharge from the oval window was repaired surgically. Extensive otologic evaluation should be conducted in patients with recurrent bacterial meningitis.
authors.affiliation: Department of Pediatrics, Kansai Medical University, Osaka, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Hayashi
authors.forename: M
authors.initials: M
authors.lastname: Kino
authors.forename: U
authors.initials: U
authors.lastname: Nobori
authors.forename: M
authors.initials: M
authors.lastname: Yanagida
authors.forename: K
authors.initials: K
authors.lastname: Ushiro
authors.forename: T
authors.initials: T
authors.lastname: Kumazawa
authors.forename: Y
authors.initials: Y
authors.lastname: Kobayashi
mesh_terms: D002558:Cerebrospinal Fluid Otorrhea / Q000150:complications; D002675:Child, Preschool; D004427:Ear Diseases / Q000150:complications; D007758:Ear, Inner / Q000002:abnormalities*; D005260:Female; D005402:Fistula / Q000150:complications; D006801:Humans; D008586:Meningitis, Pneumococcal / Q000209:etiology* / Q000382:microbiology; D012008:Recurrence