title: Exploration and habituation in Purkinje cell degeneration mutant mice.
abstract: Purkinje cell degeneration (pcd) mutant mice lose virtually all Purkinje cells. It was found that the pcd mutants did not show within-sessions habituation in terms of hole-poking responses. This type of perseverative responding has been found in rats with limbic system damage and implies a role for the cerebellum in behavioral inhibition.
authors.affiliation: Neurology Service, Hôtel-Dieu Hospital, Montreal, Canada.
authors.forename: R
authors.initials: R
authors.lastname: Lalonde
authors.forename: M
authors.initials: M
authors.lastname: Manseau
authors.forename: M I
authors.initials: MI
authors.lastname: Botez
mesh_terms: D000818:Animals; D002531:Cerebellum / Q000502:physiology*; D005106:Exploratory Behavior / Q000502:physiology*; D005260:Female; D006185:Habituation, Psychophysiologic / Q000502:physiology*; D008297:Male; D051379:Mice; D008818:Mice, Neurologic Mutants / Q000502:physiology*; D011689:Purkinje Cells / Q000502:physiology*