title: Chronic sinusitis and woodworking as risk factors for cancer of the maxillary sinus in northeast Japan.
abstract: In the period 1983 to 1985, 66 patients presented to six Japanese university hospitals with squamous cell carcinoma of the maxillary sinus. Using self-administered questionnaires, a case-control study was conducted to examine history of nasal diseases, occupational exposures, and other possible risk factors for this disease. For each patient, two controls were selected from the general population, matched to the patient by sex, age (+/- 5 years), and district of residence. A history of chronic sinusitis was associated with a 2.3-fold increase in risk (p = 0.05). A high relative risk was also observed in males with an occupational history of woodworking or joinery, particularly when these jobs involved sanding or lathing practices (RR = 7.5, p = 0.02). No association between cigarette smoking and maxillary sinus cancer was observed in this study and no evidence was found that indoor air pollution in the home is involved in cancer development.
authors.affiliation: Dept. of Public Health, Tohoku University School of Medicine, Sendai, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Shimizu
authors.forename: J
authors.initials: J
authors.lastname: Hozawa
authors.forename: H
authors.initials: H
authors.lastname: Saito
authors.forename: K
authors.initials: K
authors.lastname: Murai
authors.forename: H
authors.initials: H
authors.lastname: Hirata
authors.forename: T
authors.initials: T
authors.lastname: Takasaka
authors.forename: K
authors.initials: K
authors.lastname: Togawa
authors.forename: A
authors.initials: A
authors.lastname: Konno
authors.forename: Y
authors.initials: Y
authors.lastname: Kimura
authors.forename: A
authors.initials: A
authors.lastname: Kikuchi
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000209:etiology*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D008444:Maxillary Sinus Neoplasms / Q000209:etiology*; D008875:Middle Aged; D009784:Occupational Diseases / Q000209:etiology*; D010255:Paranasal Sinus Neoplasms / Q000209:etiology*; D012307:Risk Factors; D012852:Sinusitis / Q000150:complications*; D012907:Smoking; D014934:Wood