title: Prognostic value of serum phospholipase A in the multitraumatized patient.
abstract: Phospholipase A serum activity was prospectively studied in 39 patients with multiple trauma. There was no correlation of phospholipase A activity with type or severity of injury. With increasing phospholipase A levels, a rise in mortality was found. A prediction of fatal outcome on an individual basis was not possible. The sensitivity for complications was 90%, whereas the predictive value of the positive test (64%) and specificity (47%) were low. When the behavior of phospholipase A and elastase release were compared, no correlation between these two parameters could be detected. Therefore, PMN leukocytes do not seem to be a major source of phospholipase A in serum.
authors.affiliation: Chirurgische Klinik Innenstadt, Universität München.
authors.forename: C
authors.initials: C
authors.lastname: Waydhas
authors.forename: D
authors.initials: D
authors.lastname: Nast-Kolb
authors.forename: K H
authors.initials: KH
authors.lastname: Duswald
authors.forename: P
authors.initials: P
authors.lastname: Lehnert
authors.forename: L
authors.initials: L
authors.lastname: Schweiberer
mesh_terms: D058186:Acute Kidney Injury / Q000201:enzymology; D000293:Adolescent; D000328:Adult; D000368:Aged; D006801:Humans; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000201:enzymology; D009104:Multiple Trauma / Q000201:enzymology*; D009504:Neutrophils / Q000201:enzymology; D010196:Pancreatic Elastase / Q000097:blood; D010740:Phospholipases / Q000097:blood*; D010741:Phospholipases A / Q000097:blood*; D011379:Prognosis; D012128:Respiratory Distress Syndrome / Q000201:enzymology
chemical_list: D010740:Phospholipases; D010741:Phospholipases A; D010196:Pancreatic Elastase