Trimipramine-induced neuroleptic malignant syndrome after transient psychogenic polydipsia in one patient.
A case of neuroleptic malignant syndrome (NMS) was induced by the antidepressant trimipramine in a 47-year-old woman with obsessive compulsive disorder and major depression. NMS symptoms were associated with a brief episode of polydipsia, and both conditions may have had dopaminergic dysfunction as a common etiology. The patient improved with bromocriptine and dantrolene.
Langlow
J R
JR
Department of Psychiatry, University of Alabama School of Medicine, Birmingham.
Alarcon
R D
RD
D003866:Depressive Disorder / Q000188:drug therapy / Q000523:psychology; D003984:Dibenzazepines / Q000009:adverse effects*; D004327:Drinking Behavior; D005260:Female; D006801:Humans; D008875:Middle Aged; D009459:Neuroleptic Malignant Syndrome / Q000209:etiology*; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy / Q000523:psychology; D011602:Psychophysiologic Disorders / Q000523:psychology*; D014299:Trimipramine / Q000009:adverse effects*
D003984:Dibenzazepines; D014299:Trimipramine