Versatile supplement device with remote control for the control of patch clamp experiments.
A versatile device for a patch-clamp amplifier is described. This device contains: (i) an acoustic indicator to monitor the input resistance of the patch pipette, which is used in search-mode to indicate the formation of seals; (ii) two pulse generators; and (iii) a staircase generator to produce various pulse and voltage step programs; (iv) a low-pass filter which is used to filter the output of the patch clamp amplifier; and (v) a remote control which is used to control the entire patch clamp experiment. This remote control is used to switch between search-, current clamp-, and voltage clamp-mode, to activate the respective stimulus potential programs, and to control the tape recorder. This electronic device can be easily connected to patch clamp amplifiers.
Rohlicek
V
V
Physiological Institute CSAV, Prague, Czechoslovakia.
Fröbe
U
U
Gögelein
H
H
Greger
R
R
D000818:Animals; D004594:Electrophysiology / Q000295:instrumentation*