title: Determination of methadone in human hair by radioimmunoassay.
abstract: The concentrations of methadone in human hair were measured. The washed hair was cut in 1-mm pieces approximately, then incubated overnight at 45 degrees C with 0.1 m HCl. The extracts were alcalized by 1 m NaOH and diluted by phosphate buffer, pH 7.4. The methadone concentrations were determined by radioimmunoassay. The method is simple, rapid, and practicable for routine determination.
authors.affiliation: Department of Forensic Medicine, University of Ulm, Federal Republic of Germany.
authors.forename: S
authors.initials: S
authors.lastname: Balabanova
authors.forename: H U
authors.initials: HU
authors.lastname: Wolf
mesh_terms: D006197:Hair / Q000032:analysis*; D006801:Humans; D008691:Methadone / Q000032:analysis* / Q000627:therapeutic use; D009293:Opioid-Related Disorders / Q000534:rehabilitation; D011863:Radioimmunoassay
chemical_list: D008691:Methadone