[Experiences of immunologic phenotyping in acute leukemia].
Phenotyping of leukemic cells with monoclonal antibodies usually confirms the morphological classification in acute lymphoblastic and acute myeloid leukemia. Immunological phenotyping gives a more detailed subclassification and may add information on the stage of differentiation of the leukemic cells. This may have prognostic implications, and in the future may influence the choice of treatment modalities. It is not unusual for the leukemic cells to carry both myeloid and lymphoid markers. For such leukemias the prognosis is poor. We describe our experience from immunological phenotyping of 46 acute myeloid and 35 acute lymphoblastic leukemias.
Brinch
L
L
Evensen
S A
SA
Stavem
P
P
Smeland
E B
EB
D000208:Acute Disease; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000276:immunology; D010641:Phenotype; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics* / Q000276:immunology
Erfaringer med immunologisk fenotyping av akutte leukemier.