title: Steroid metabolism in the testes of the breeding and nonbreeding three-spined stickleback, Gasterosteus aculeatus.
abstract: Steroid metabolism in the testes of sticklebacks was studied in vitro by tissue incubations with [3H]pregnenolone or [3H]androstenedione as precursors. In males in full reproductive condition (nesting), [3H]pregnenolone was mainly converted via progesterone and 17 alpha-hydroxyprogesterone into androstenedione, 11 beta-hydroxyandrostenedione, and 11-ketoandrostenedione. The latter was the largest product formed. The main products from the [3H]androstenedione incubation, 11 beta-hydroxyandrostenedione and 11-ketoandrostenedione, confirm these findings. The rate of androgen synthesis, especially of 11-ketoandrostenedione, was much lower after the end of the breeding season.
authors.affiliation: Department of Zoology, University of Stockholm, Sweden.
authors.forename: B
authors.initials: B
authors.lastname: Borg
authors.forename: W G
authors.initials: WG
authors.lastname: Schoonen
authors.forename: J G
authors.initials: JG
authors.lastname: Lambert
mesh_terms: D000736:Androstenes / Q000378:metabolism*; D000818:Animals; D001947:Breeding; D002855:Chromatography, Thin Layer; D005399:Fishes / Q000378:metabolism*; D008297:Male; D011374:Progesterone / Q000378:metabolism*; D013737:Testis / Q000378:metabolism*
chemical_list: D000736:Androstenes; D011374:Progesterone