Organization of repetitive DNAs in the guinea pig genome.
Investigation of restriction enzyme families observed in Bam HI and Eco RI digest of guinea pig DNA has led to the demonstration of a 4.0 kb cryptic satellite called MRICp which has 6300 copies and comprises 1% of the total genome. MRICp has been shown to encompass the Eco RI 4.0 kb family, the Bam HI 3.4 kb family and the Bam HI 3.7 kb family. The 1.5 kb Eco RI family is part of an L1 LINE that is present in the guinea pig and in other rodentia. It is part of a larger LINE, probably 6.5 to 7 kb in size, and some copies are embedded in satellite I DNA sequences.
Spencer
J H
JH
Department of Biochemistry, Queen's University, Kingston, Ontario, Canada.
Fredenburgh
J C
JC
Sivilotti
M
M
D'Souza
C R
CR
D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004262:DNA Restriction Enzymes; D004276:DNA, Satellite / Q000032:analysis; D004587:Electrophoresis, Agar Gel; D006168:Guinea Pigs / Q000235:genetics*; D008969:Molecular Sequence Data; D012150:Polymorphism, Restriction Fragment Length; D012091:Repetitive Sequences, Nucleic Acid; D015183:Restriction Mapping
D004276:DNA, Satellite; D004262:DNA Restriction Enzymes