Association of IgA nephropathy and myasthenia gravis.
Three patients with IgA nephropathy associated with myasthenia gravis are described. In all 3 cases, myasthenia gravis emerged after the discovery of glomerulonephritis. Myasthenic symptoms were improved by thymectomy in 2 cases, but progression of the renal disease was not improved. Some systemic abnormalities, including immunological aberrations, were observed in these two disorders. It is postulated that T cell abnormalities in IgA nephropathy might be independent of the development of myasthenia gravis.
Miyazaki
M
M
Department of Internal Medicine, School of Medicine, Tokai University, Kanagawa-Ken, Japan.
Kimura
N
N
Imai
K
K
Eguchi
K
K
Yagame
M
M
Miura
M
M
Endoh
M
M
Tomino
Y
Y
Nomoto
Y
Y
Sakai
H
H
D000328:Adult; D005260:Female; D005922:Glomerulonephritis, IGA / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications* / Q000473:pathology