title: [Retrospective comparative study of treatment with delayed-action neuroleptics and neuroleptics administrated orally in long-term psychosis].
abstract: Through a retrospective study, we have tried to compare the indication spectrum and efficacy of depot neuroleptics versus oral neuroleptics on two hundred patients suffering from long term psychosis. For each group, we selected one hundred patients who met the following requirements: the minimal duration of chemotherapy was of 3 years, the patients were aged 16 to 60. Patients receiving depot neuroleptics, although their original prognosis were worse than those of patients receiving oral neuroleptics, obtained the same good results concerning most semiological, chemotherapeutic and institutional criteria. However, good results for patients receiving depot neuroleptics must be qualified because of a more important number of chronic and defect states and a lack of autonomy.
authors.affiliation: Service du Pr Marie-Cardine, C.H.S. Le Vinatier, Bron.
authors.forename: O
authors.initials: O
authors.lastname: Chambon
authors.forename: M
authors.initials: M
authors.lastname: Marie-Cardine
authors.forename: J L
authors.initials: JL
authors.lastname: Terra
authors.forename: P
authors.initials: P
authors.lastname: Corot
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003692:Delayed-Action Preparations; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011618:Psychotic Disorders / Q000188:drug therapy*; D012189:Retrospective Studies; D013223:Statistics as Topic
chemical_list: D014150:Antipsychotic Agents; D003692:Delayed-Action Preparations
vernacular_title: Etude rétrospective comparative des traitements neuroleptiques d'action prolongée et des traitements neuroleptiques par voie orale dans les psychoses au long cours.