Thromboembolic risk factors in patients undergoing maxillofacial surgery for malignancies.
Venous thromboembolism is a common complication in patients undergoing major surgery. We studied blood coagulation profiles in 16 patients undergoing extensive maxillofacial surgery for oral malignant diseases. Activity of coagulation factor V and levels of antithrombin III were significantly reduced on the first postoperative day. Fibrinogen level showed a continuous increase throughout the observation period. However, no thromboembolic events were observed. It can be concluded that despite a severe alteration of the blood clotting system, maxillofacial surgery does not seem to be associated with postoperative thromboembolism.
Watzke
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Department of Oral and Maxillofacial Surgery, University of Vienna, Austria.
Watzke
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H
D001779:Blood Coagulation Factors / Q000032:analysis; D001780:Blood Coagulation Tests; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D005260:Female; D006258:Head and Neck Neoplasms / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection / Q000009:adverse effects*; D011446:Prospective Studies; D013923:Thromboembolism / Q000209:etiology*
D001779:Blood Coagulation Factors