Acute myelogenous leukemia treated with daunomycin associated with nephrotic syndrome.
We report a 33-year-old patient with a diagnosis of acute myelogenous leukemia that developed a nephrotic syndrome 9 days after starting treatment with daunomycin. Pathological studies of the kidneys revealed minimal change disease with IgM deposits. Possible pathogenetic mechanisms are discussed.
Thomson
M
M
Servicios de Medicina Interna, Nefrología y Anatomía Patológica, Fundación Jiménez Díaz, Madrid, Spain.
de Arriba
G
G
Ordi
J
J
Oliva
H
H
Hernando
L
L
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003561:Cytarabine / Q000008:administration & dosage; D003630:Daunorubicin / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007668:Kidney / Q000473:pathology; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000188:drug therapy*; D008297:Male; D009404:Nephrotic Syndrome / Q000209:etiology*
D003561:Cytarabine; D003630:Daunorubicin