Dermatitis produced by applications of monobenzone in patients with active vitiligo.
Six patients with spreading vitiligo treated with applications of monobenzone developed a vesicular dermatitis. The eruption was restricted exclusively to the pigmented areas of the skin. Patch tests applied to pigmented and depigmented skin produced an inflammatory response only within the pigmented areas. The explanation for this puzzling phenomenon is not known.
Nordlund
J J
JJ
Forget
B
B
Kirkwood
J
J
Lerner
A B
AB
D000328:Adult; D003879:Dermatologic Agents / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D006873:Hydroquinones / Q000009:adverse effects*; D008875:Middle Aged; D010328:Patch Tests; D012880:Skin Pigmentation / Q000187:drug effects*; D014820:Vitiligo / Q000188:drug therapy* / Q000473:pathology
D003879:Dermatologic Agents; D006873:Hydroquinones; C006429:monobenzone