Fine needle aspiration cytology of metastatic lymphoepithelioma. A case report.
A case is presented of lymphoepithelioma (undifferentiated nasopharyngeal carcinoma) metastatic to the cervical lymph nodes in a 12-year-old boy for whom material was obtained by fine needle aspiration (FNA) for the primary diagnosis as well as for ancillary studies. Papanicolaou-stained smears demonstrated the characteristic cytopathologic features of Regaud-type lymphoepithelioma; the diagnosis was substantiated by immunocytochemical and electron microscopic studies. This report discusses the reliability and rapidity of FNA in definitively diagnosing undifferentiated metastatic malignancies as well as providing superior material for ancillary studies demanded by lesions with complicated and difficult differential diagnoses.
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Department of Pathology and Laboratory Medicine, University of Texas Health Science Center, Houston 77225.
Raval
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Schmidt
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D001707:Biopsy, Needle; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000473:pathology; D002648:Child; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D009303:Nasopharyngeal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D009362:Neoplasm Metastasis