Treatment of the young child with postoperative central diabetes insipidus.
A continuous intravenous infusion of aqueous vasopressin (dosage range, 1.0 to 3.0 mU/kg/h) was administered to two patients (respective ages, 2 weeks and 3 years 1 month) who had postoperative central diabetes insipidus to determine if this mode of therapy is helpful in the very young patient. In both patients the polyuria and serum hyperosmolality were corrected. These findings suggest that an intravenous infusion of aqueous vasopressin can provide satisfactory control of the polyuria and electrolyte disturbances found in young children with acute postoperative central diabetes insipidus.
McDonald
J A
JA
Department of Pediatrics, University of Virginia School of Medicine, Charlottesville 22908.
Martha
P M
PM
Kerrigan
J
J
Clarke
W L
WL
Rogol
A D
AD
Blizzard
R M
RM
D001921:Brain / Q000601:surgery*; D002675:Child, Preschool; D003919:Diabetes Insipidus / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D008297:Male; D011183:Postoperative Complications; D014667:Vasopressins / Q000008:administration & dosage / Q000627:therapeutic use
D014667:Vasopressins