title: Restriction fragment length polymorphism of the human C3 complement gene.
abstract: A cloned gene-specific probe for human complement (C3) was hybridized to DNA samples digested with various restriction endonucleases. The C3 probe detects one restriction fragment length polymorphism (RFLP) that occurs frequently in the French population when DNAs are digested with Sac I. The corresponding DNA alleles can be readily used in linkage analysis of loci on chromosome 19, and such a polymorphism can be followed through myotonic dystrophy families.
authors.affiliation: Laboratoire de Génétique Moléculaire du CNTS, Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Dandieu
authors.forename: G
authors.initials: G
authors.lastname: Lucotte
mesh_terms: D002888:Chromosomes, Human, Pair 19; D003176:Complement C3 / Q000235:genetics*; D015342:DNA Probes; D005819:Genetic Markers; D006801:Humans; D009223:Myotonic Dystrophy / Q000235:genetics; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D003176:Complement C3; D015342:DNA Probes; D005819:Genetic Markers