[Activity of short-lived suppressor lymphocytes in rheumatoid arthritis].
Activity of short-lived suppressor lymphocytes was studied in 26 patients with rheumatoid arthritis. Of these, 14 patients had diverse systemic manifestations: rheumatoid nodules, polyneuropathy. Sjögren's syndrome, and Felty's syndrome. It was established that attenuation of the suppressor activity in rheumatoid arthritis is characteristic of patients with systemic manifestations, who show a high level of circulating immune complexes of rheumatoid factors. The most informative data were obtained as a result of the use of the suboptimal dose of Con A having suppressor activity.
Vasil'eva
E V
EV
Nasonov
E L
EL
Mazneva
L M
LM
Saĭkovskiĭ
R K
RK
Sura
V V
VV
D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000276:immunology*; D002470:Cell Survival; D003208:Concanavalin A / Q000494:pharmacology; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D007958:Leukocyte Count; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D011043:Pokeweed Mitogens / Q000494:pharmacology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*; D013997:Time Factors
D011043:Pokeweed Mitogens; D003208:Concanavalin A
Aktivnost' korotkozhivushchikh supressornykh limfotsitov pri revmatoidnom artrite.