title: Nicardipine in the elderly hypertensive: a review of experience in the United Kingdom.
abstract: Clinical trials in the United Kingdom have supported those conducted elsewhere in showing that nicardipine is an effective antihypertensive drug in the elderly, with a tendency to produce lower diastolic blood pressure than in younger patients. Side effects are mainly related to vasodilation and are no more common than in younger patients. Nicardipine does not cause any chronic activation of the sympathetic nervous system or the renin-angiotensin system.
authors.affiliation: Department of Cardiovascular Medicine, University of Birmingham, England.
authors.forename: W A
authors.initials: WA
authors.lastname: Littler
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008875:Middle Aged; D009529:Nicardipine / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D009529:Nicardipine