[DNA-bound lipids of the cells of Zajdela ascites hepatoma and of Ehrlich ascites cancer].
DNA-bound neutral lipids (NL) and phospholipids (PL) were isolated and characterized from the Zajdel ascites hepatoma (ZAH) and Ehrlich ascites carcinoma (EAC) cells. The lipids are represented by light- and tightly bound components. It was shown, that the tumour DNA contained minor amount of NL (25, 17 micrograms and 16.87 micrograms per mg DNA, respectively) and of PL (4.54 micrograms and 5.36 micrograms per mg DNA, respectively, for ZAH and EAC). The composition of the tumour DNA-bound lipids was shown to differ from that of DNA-bound lipids of liver and thymus of intact rats by the next parameters: NL/PL ratio is much more than one; increased content of FC; equal values of the three basic ratios--CE/FC, NL/PL, cholesterol/PL, presence of mono- and triglycerides.
Struchkov
V A
VA
Strazhevskaia
N B
NB
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000032:analysis / Q000378:metabolism*; D002855:Chromatography, Thin Layer; D004273:DNA, Neoplasm / Q000032:analysis / Q000378:metabolism*; D050356:Lipid Metabolism; D008055:Lipids / Q000032:analysis; D008099:Liver / Q000032:analysis / Q000378:metabolism; D008114:Liver Neoplasms, Experimental / Q000032:analysis / Q000378:metabolism*; D008297:Male; D051379:Mice; D010743:Phospholipids / Q000032:analysis / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013950:Thymus Gland / Q000032:analysis / Q000378:metabolism
D004273:DNA, Neoplasm; D008055:Lipids; D010743:Phospholipids
DNK-sviazannye lipidy kletok astsitnoĭ gepatomy Zaĭdela i astsitnogo raka Erlikha.