Cloning of a putative neuronal nicotinic acetylcholine receptor subunit.
A cDNA clone was isolated from a rat superior cervical ganglion cDNA library with an oligonucleotide that hybridized to muscle-like nicotinic acetylcholine receptor (nAChR) subunit cDNA. The deduced amino acid sequence possesses characteristics expected of a nAChR subunit that does not bind acetylcholine, in addition to distinctive features such as unique cysteine residues and N-linked glycosylation sites.
Isenberg
K E
KE
Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110.
Meyer
G E
GE
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D003545:Cysteine; D004247:DNA / Q000235:genetics / Q000302:isolation & purification; D005728:Ganglia, Sympathetic / Q000032:analysis*; D006031:Glycosylation; D008969:Molecular Sequence Data; D009693:Nucleic Acid Hybridization; D015345:Oligonucleotide Probes; D051381:Rats; D011978:Receptors, Nicotinic / Q000235:genetics*
D015345:Oligonucleotide Probes; D011978:Receptors, Nicotinic; D004247:DNA; D003545:Cysteine