title: [Plasma digoxin levels following treatment with metaclazepam].
abstract: Nine cardiac patients treated with digitalis participated in a 3-week study with the aim to investigate whether digoxin (beta-acetyldigoxin) interacts with the new 1,4-benzodiazepine metaclazepam. Comparison of the plasma digoxin levels under placebo and metaclazepam treatment showed no statistically significant differences, i.e. no interactions between digoxin and metaclazepam were found.
authors.affiliation: Sonnenhof-Klinik, Bad Oeynhausen.
authors.forename: D
authors.initials: D
authors.lastname: Völker
authors.forename: R
authors.initials: R
authors.lastname: Müller
authors.forename: C
authors.initials: C
authors.lastname: Günther
authors.forename: R
authors.initials: R
authors.lastname: Bode
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D014151:Anti-Anxiety Agents / Q000009:adverse effects*; D001569:Benzodiazepines / Q000009:adverse effects*; D004077:Digoxin / Q000097:blood* / Q000493:pharmacokinetics; D004347:Drug Interactions; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D004077:Digoxin; C036366:metaclazepam
vernacular_title: Digoxin-Plasmaspiegel während der Behandlung mit Metaclazepam.