Equine disease association studies: a clinician's perspective.
Diagnostic criteria should be carefully defined and described in disease association studies to allow (1) comparison among studies from different laboratories evaluating the same disease, (2) critical evaluation of selection procedures of patients, and (3) to strengthen genuine associations with any genetic marker system. Factors to consider include age at onset of disease, specialized diagnostic methods necessary to diagnose or eliminate patients with a selected disease, ranges of affectedness and differences in sex expression.
McClure
J J
JJ
Louisiana State University, School of Veterinary Medicine, Department of Veterinary Clinical Sciences, Baton Rouge 70803.
D000818:Animals; D001193:Arytenoid Cartilage; D001847:Bone Diseases / Q000175:diagnosis / Q000662:veterinary; D002357:Cartilage Diseases / Q000175:diagnosis / Q000662:veterinary; D003456:Cryptorchidism / Q000175:diagnosis / Q000662:veterinary; D003937:Diagnosis, Differential; D006554:Hernia, Umbilical / Q000175:diagnosis / Q000662:veterinary; D006734:Horse Diseases / Q000145:classification / Q000175:diagnosis*; D006736:Horses; D008173:Lung Diseases, Obstructive / Q000175:diagnosis / Q000662:veterinary; D008297:Male; D010243:Paralysis / Q000175:diagnosis / Q000662:veterinary; D012107:Research Design; D012878:Skin Neoplasms / Q000175:diagnosis / Q000662:veterinary