Antipsychotic withdrawal phenomena in the medical-surgical setting.
The literature describing nondyskinetic antipsychotic withdrawal symptoms is reviewed. The withdrawal of antipsychotic agents can result in nausea, emesis, anorexia, diarrhea, rhinorrhea, diaphoresis, myalgias, paresthesias, anxiety, agitation, restlessness, and insomnia. Psychotic relapse is often presaged by increased anxiety, agitation, restlessness, and insomnia. However, the temporal relationship of these prodromal symptoms to reduction in the dosage or discontinuation of neuroleptics distinguishes them from the effects of abrupt withdrawal.
Dilsaver
S C
SC
Department of Psychiatry, Ohio State University, Columbus 43210-1228.
Coffman
J A
JA
D000928:Antidepressive Agents / Q000009:adverse effects; D000978:Antiparkinson Agents / Q000009:adverse effects; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D011618:Psychotic Disorders / Q000188:drug therapy*; D012017:Referral and Consultation; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy*; D013503:Surgery Department, Hospital
D000928:Antidepressive Agents; D000978:Antiparkinson Agents; D014150:Antipsychotic Agents