[Anti-psoriasis and phototoxic effect of a hematoporphyrin derivative following topical administration and irradiation with visible light].
An ointment, consisting of 100 micrograms hematoporphyrin derivative +5.0 ml dimethylsulfoxide +95.0 ml Unguentum Alcoholum lanae SR, was checked for both phototoxic and antipsoriatic efficacy. After topical application and irradiation with visible light or ultraviolet radiation, healthy skin showed delayed erythemas, whereas psoriasis plaques improved markedly.
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D000293:Adolescent; D000328:Adult; D005260:Female; D006414:Hematoporphyrin Photoradiation / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010778:Photochemotherapy / Q000009:adverse effects*; D010787:Photosensitivity Disorders / Q000139:chemically induced*; D011565:Psoriasis / Q000188:drug therapy*; D012307:Risk Factors
Antipsoriatische und phototoxische Wirksamkeit von Hämatoporphyrin-Derivat nach topischer Applikation und Bestrahlung mit sichtbarem Licht.