title: Results of radiation therapy in early glottic carcinoma (T1, T2 N0).
abstract: Glottic carcinoma is curable by either surgery or radiotherapy. A total of 60 patients were treated by radiation alone at the Northern Israel Oncology Center, Rambam Medical Center, Haifa, between 1970 and 1980. Twenty-nine (48%) were classified as T1 N0 and 31 (52%) as T2 N0. All patients received radiotherapy primarily with curative intent, with surgery reserved for recurrences. The 5-year actuarial survival for all patients was 90% and actuarial disease-free survival was 95%. In ten patients (17%) there was local failure, and five of them were salvaged by surgery. There were no significant acute or long-term complications of radiation. Factors influencing treatment outcome (anterior commissures involvement, degree of differentiation, treatment volume, and technique of irradiation) and the occurrence of second primary malignancies are discussed.
authors.affiliation: Northern Israel Oncology Center, Rambam Medical Center, Haifa.
authors.forename: M
authors.initials: M
authors.lastname: Stein
authors.forename: E
authors.initials: E
authors.lastname: Rosenblatt
authors.forename: A
authors.initials: A
authors.lastname: Kuten
authors.forename: Y
authors.initials: Y
authors.lastname: Cohen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D005500:Follow-Up Studies; D005931:Glottis; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D011878:Radiotherapy / Q000009:adverse effects; D011879:Radiotherapy Dosage