Significance of squamous cell carcinoma-related antigen in psoriasis and generalized eczema. Preliminary report.
The serum levels of squamous cell carcinoma-related antigen (SCC-RAG) were assayed in 15 cases of benign dermatoses. The SCC-RAG titers (2.0 ng/ml as the cutoff value) were elevated in all cases of wide-spreading psoriasis (7 cases, 2.4-96.1 ng/ml) and all cases of generalized eczema (3 cases, 11.2-33.6 ng/ml). The serum SCC-RAG levels correlated with clinical course of these dermatoses. Therefore, the increase in this cancer-related antigen is not specific for SCC but may also occur in a wide range of dermatoses.
Numahara
T
T
Department of Dermatology, Kagawa Medical School, Japan.
Nakashima
K
K
Yamamoto
S
S
Nishimoto
M
M
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000951:Antigens, Neoplasm / Q000032:analysis*; D004485:Eczema / Q000276:immunology*; D006801:Humans; D008875:Middle Aged; D011565:Psoriasis / Q000276:immunology*; D011863:Radioimmunoassay; D015843:Serpins
D000951:Antigens, Neoplasm; D015843:Serpins; C051072:squamous cell carcinoma-related antigen