[Cytochemical study of the neurocytes of the rat locus coeruleus after guanethidine sympathectomy].
The histone localization, template activity of chromatin and epinephrine fluorescence in L. Coeruleus (LC) neurons of normal a. guanethidine sympathectomized (GS) rats (15 mg/kg during 3, 8 or 14 days after birth) were studied. The absence of chromatin rearrangements connected with genome reprogramming under sympathectomy was documented by the fact that maximal doses of guanethidine gives no changes in ammoniacal silver staining pattern. However GS caused the decrease in nuclear and extranuclear template activity and in epinephrine fluorescence proportionally with GS. It is obvious that LC cells tend to form discrete classes according to their transcription levels.
Altan
G
G
Iarygin
V N
VN
Grigor'eva
A V
AV
D000818:Animals; D003592:Cytophotometry; D003593:Cytoplasm / Q000378:metabolism; D006145:Guanethidine; D006651:Histocytochemistry; D006657:Histones / Q000378:metabolism; D008125:Locus Coeruleus / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism*; D009562:Nissl Bodies / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism; D051381:Rats; D013563:Sympathectomy, Chemical; D014158:Transcription, Genetic
D006657:Histones; D009638:Norepinephrine; D006145:Guanethidine
Tsitokhimicheskoe issledovanie nevrotsitov locus coeruleus krys pri desimpatizatsii guanetidinom.