[Allergy and desensitization to hymenoptera venom in children].
Among 15 children who were stung by hymenoptera, 5 underwent semi-rapid desensitization using the outpatient Molkhou method. This technique was well tolerated; desensitization was stopped when protective IgG levels measured by RIP (radioimmunoprecipitation) reached 50% and skin tests and RASTs became negative. In a comparable series of adults, however, discontinuation of the desensitization was considered only following satisfactory tolerance of an accidental or planned sting. In children, semi-rapid desensitization is very effective and has also been proposed for allergies to air borne allergens such as mites and pollens when increased doses are required to improve protection.
Marchand
J C
JC
Battin
J
J
D000293:Adolescent; D000818:Animals; D001180:Arthropod Venoms / Q000009:adverse effects*; D002648:Child; D003888:Desensitization, Immunologic / Q000379:methods; D005260:Female; D006801:Humans; D006927:Hymenoptera; D006967:Hypersensitivity / Q000628:therapy*; D007074:Immunoglobulin G / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D011852:Radioallergosorbent Test; D012882:Skin Tests
D001180:Arthropod Venoms; D007074:Immunoglobulin G
Allergie et désensibilisation au venin d'hyménoptère chez l'enfant.