title: An evaluation of Tourette syndrome and medication use in Canada.
abstract: Self-report data were gathered from a national sample of over 200 Canadian Tourette Syndrome (TS) patients. Information regarding symptom severity both on and off medication was gathered along with an analysis of different medications in use, and patient ratings of effectiveness of those medications. Patients also rated their own mental health. Results indicated that approximately 60% of TS patients take some form of medication for relief from their symptoms. Of these, over 80% reported that symptoms are less severe when medicated. The most commonly prescribed medications in order of popularity are haloperidol, pimozide, clonidine and benztropine mesylate (Cogentin). Patient ratings of effectiveness of these medications places haloperidol first, pimozide second and clonidine third although all were found to be "somewhat" to "very" effective. Of those TS patients on medications, 50% rated their own mental health as good to excellent and 50% rated it as fair to poor.
authors.affiliation: Department of Psychiatry, St. Boniface General Hospital, Winnipeg, Manitoba, Canada.
authors.forename: W A
authors.initials: WA
authors.lastname: Fulton
authors.forename: G A
authors.initials: GA
authors.lastname: Shady
authors.forename: L M
authors.initials: LM
authors.lastname: Champion
mesh_terms: D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D002170:Canada; D002648:Child; D002675:Child, Preschool; D005260:Female; D006220:Haloperidol / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D010868:Pimozide / Q000627:therapeutic use*; D005879:Tourette Syndrome / Q000188:drug therapy*
chemical_list: D014150:Antipsychotic Agents; D010868:Pimozide; D006220:Haloperidol