title: A longitudinal study of thyroid function in pregnancy.
abstract: We undertook a prospective longitudinal study of thyroid function in 36 pregnant women. There were significant increases in thyroxin-binding globulin, thyrotropin, and triiodothyronine. Albumin, free thyroxin (measured by an analog and a nonanalog method), and the free thyroxin index were significantly decreased. Results for the free thyroxin methods were correlated with each other in each trimester. We could find no evidence for artifacts related to albumin or thyroxin-binding globulin with either method for free thyroxin.
authors.affiliation: Department of Clinical Chemistry, Northern General Hospital, Sheffield, U.K.
authors.forename: A
authors.initials: A
authors.lastname: Price
authors.forename: H
authors.initials: H
authors.lastname: Griffiths
authors.forename: B W
authors.initials: BW
authors.lastname: Morris
mesh_terms: D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D011247:Pregnancy / Q000097:blood* / Q000502:physiology; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D011446:Prospective Studies; D012709:Serum Albumin / Q000032:analysis; D013963:Thyroid Hormones / Q000097:blood*
chemical_list: D012709:Serum Albumin; D013963:Thyroid Hormones