title: [Prevention of infection in teflon prostheses for dialysis access. Experiences with a resorbable combined collagen-antibiotic system].
abstract: 40 patients with renal insufficiency and chronic hemodialysis received a E-PTFE prosthesis as vascular access either at the upper or lower extremity. The efficacy of prophylaxis of infection through application of a local aminoglycosid, administered as a resorbable collagen-antibiotic-sponge, was studied in two different groups. All patients had a high risk of infection. The use of the collagen-gentamycin-sponge was effective in preventing an infection of the vascular graft. Systemic side effects were not registrated in spite of the reduced renal function. Further studies are necessary to evaluate the efficacy of the collagen-gentamycin-sponge in preventing vascular prosthesis infection in high risk patients.
authors.forename: R
authors.initials: R
authors.lastname: Horch
authors.forename: G
authors.initials: G
authors.lastname: Krönung
mesh_terms: D000328:Adult; D000368:Aged; D001166:Arteriovenous Shunt, Surgical; D001807:Blood Vessel Prosthesis; D003094:Collagen; D004343:Drug Implants; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011138:Polytetrafluoroethylene; D006435:Renal Dialysis; D013530:Surgical Wound Infection / Q000517:prevention & control*
chemical_list: D004343:Drug Implants; D005839:Gentamicins; D011138:Polytetrafluoroethylene; D003094:Collagen
vernacular_title: Infektprophylaxe bei Teflonprothesen für den Dialysezugang. Erfahrungen mit einem resorbierbaren Kollagen-Antibiotikum-Verbundsystem.