Electron impact induced fragmentations of the 1,4-diene analogues of steroid hormones and related steroids.
The electron impact induced fragmentations observed in the mass spectra of eight 1,4-diene-3-ketopregnane steroids are described. The effect of hydroxyl substituents in positions 11 beta, 17 alpha and 21, on the typical fragmentation pattern is analysed; in particular the 'long range' effect of the 17 alpha-hydroxy group on the relative abundance of the ions m/z 121 and 122 is confirmed using specific deuterium labelling.
Gonzalez
M D
MD
Burton
G
G
D003903:Deuterium; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D011245:Pregnadienes / Q000032:analysis*; D011282:Pregnenediones / Q000032:analysis*
D011245:Pregnadienes; D011282:Pregnenediones; D003903:Deuterium