title: Quantification of progressive diabetic macular nonperfusion.
abstract: We used the IS-2000 Image Analyzer to estimate the extent of progressive diabetic macular nonperfusion in a patient by means of an automatic clustering algorithm applied to digitized fluorescein angiograms of the patient's macula taken over time. This method may provide an objective and reproducible quantification of progressive macular nonperfusion.
authors.affiliation: Retina Service, Wills Eye Hospital, Philadelphia, PA 19107.
authors.forename: R E
authors.initials: RE
authors.lastname: Goldberg
authors.forename: R
authors.initials: R
authors.lastname: Varma
authors.forename: G L
authors.initials: GL
authors.lastname: Spaeth
authors.forename: L E
authors.initials: LE
authors.lastname: Magargal
authors.forename: D
authors.initials: D
authors.lastname: Callen
mesh_terms: D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D003930:Diabetic Retinopathy / Q000473:pathology*; D005451:Fluorescein Angiography; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008268:Macular Degeneration / Q000473:pathology*; D008297:Male; D014792:Visual Acuity