Chronic myelogenous leukemia and Klinefelter's syndrome.
A case of chronic myelogenous leukemia with Klinefelter's syndrome mosaicism in a 27-yr-old male is reported. Cytogenetic analysis provided evidence that the Philadelphia chromosome occurred monoclonally in the XXY cells but not in the XY cells.
Oguma
N
N
Department of Hematology, Hiroshima University, Japan.
Takemoto
M
M
Oda
K
K
Tanaka
K
K
Shigeta
C
C
Sakatani
K
K
Kamada
N
N
Kuramoto
A
A
D000293:Adolescent; D000328:Adult; D006801:Humans; D007621:Karyotyping; D007713:Klinefelter Syndrome / Q000150:complications* / Q000235:genetics; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications* / Q000235:genetics; D008297:Male; D008875:Middle Aged; D010677:Philadelphia Chromosome