Essential fatty acids in plasma phospholipids in schizophrenics.
Blood samples were taken from schizophrenics and control patients in three different centers. The phospholipids were extracted from plasma and their fatty acid composition analyzed. Similar and consistent differences between schizophrenics and controls were observed at all three centers. The n-6 essential fatty acid levels were significantly reduced, whereas n-3 essential fatty acids were elevated.
Horrobin
D F
DF
Efamol Research Institute, Kentville, Nova Scotia, Canada.
Manku
M S
MS
Morse-Fisher
N
N
Vaddadi
K S
KS
Courtney
P
P
Glen
A I
AI
Glen
E
E
Spellman
M
M
Bates
C
C
D000328:Adult; D004409:Dyskinesia, Drug-Induced / Q000097:blood; D005228:Fatty Acids, Essential / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010743:Phospholipids / Q000097:blood*; D012559:Schizophrenia / Q000097:blood*
D005228:Fatty Acids, Essential; D010743:Phospholipids