title: General anesthesia and fragile X syndrome: report of a case.
abstract: A case report of an 11-year-old Caucasian boy with the fragile X syndrome is presented. The fragile X syndrome is a form of X-linked mental retardation with a connective tissue component that involves mitral valve prolapse. Antibiotic prophylaxis, electrocardiographic abnormalities, and special anesthetic management considerations are elements of treating patients with fragile X syndrome. The patient received morphine sulfate and scopolamine as a preoperative premedication. Ketamine was also administered intramuscularly prior to induction to gaseous anesthetic. Pancuronium was used to facilitate nasotracheal intubation. A wandering atrial pacemaker and progressive hypocapnia, both of which were managed without complication, were the only problems encountered in the anesthetic procedure.
authors.forename: P S
authors.initials: PS
authors.lastname: Casamassimo
authors.forename: W B
authors.initials: WB
authors.lastname: Mcllvaine
authors.forename: R
authors.initials: R
authors.lastname: Hagerman
authors.forename: W C
authors.initials: WC
authors.lastname: Shellhart
mesh_terms: D000766:Anesthesia, Dental; D000768:Anesthesia, General; D002648:Child; D003730:Dental Care for Persons with Disabilities / Q000379:methods; D005600:Fragile X Syndrome / Q000503:physiopathology; D006801:Humans; D008297:Male; D012729:Sex Chromosome Aberrations / Q000503:physiopathology