title: [Follow-up study of 48 athletes with stage I hypertension with and without pharmacotherapy].
abstract: We found in an earlier investigation that the frequency of hypertension is considerably lower among male athletes than in a random sample of the general population. The cases of hypertension in younger athletes are primarily hypertension stage I (WHO). We followed up on the question of the course of hypertension stage I and the possibility of spontaneous remission. For this, we observed 28 nonmedicated patients with hypertension stage I for 4.2 +/- 2.3 years, 20 patients undergoing drug therapy for 2.5 +/- 1.3 years, and 12 healthy athletes for 4.2 +/- 2.2 years. Under drug therapy, as expected, there was a normalization of both basic and exercise blood pressures. Fifty percent of patients without drug therapy showed remission of the elevated basic and exercise pressures after 2 to 3 years; 50% had an unchanged high pressure or deterioration. The transition of hypertension WHO stage I to stage II with regard to left ventricular hypertrophy could be ruled out echocardiographically in patients with a favorable course (remission). However, there was a tendency in this direction among patients with the least favorable course.
authors.affiliation: Medizinische Universitätsklinik Freiburg im Breisgau, Abt. Sport- und Leistungsmedizin.
authors.forename: M
authors.initials: M
authors.lastname: Lehmann
authors.forename: H
authors.initials: H
authors.lastname: Merkelbach
authors.forename: U
authors.initials: U
authors.lastname: Gastmann
authors.forename: J
authors.initials: J
authors.lastname: Keul
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects*; D002306:Cardiac Volume / Q000187:drug effects; D004452:Echocardiography; D005080:Exercise Test; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D013177:Sports; D014700:Verapamil / Q000627:therapeutic use
chemical_list: D000319:Adrenergic beta-Antagonists; D000959:Antihypertensive Agents; D014700:Verapamil
vernacular_title: Verlaufsbeobachtung bei 48 Sportlern mit Hypertonie im Stadium I mit und ohne Pharmakotherapie.