title: Cranio-vertebral pathology in Down syndrome.
abstract: Cranio-vertebral malformations, especially atlanto-axial dislocation, are frequently seen in Down patients. However, symptomatic forms in mongolism are rare. Pyramidal signs have a signal value. In symptomatic malformations surgical treatment should be advised, i.e. posterior fixation after pre-operative reduction by traction or transoral odontoidectomy if no reduction is achieved.
authors.forename: J P
authors.initials: JP
authors.lastname: Braakhekke
authors.forename: F J
authors.initials: FJ
authors.lastname: Gabreëls
authors.forename: W O
authors.initials: WO
authors.lastname: Renier
authors.forename: T J
authors.initials: TJ
authors.lastname: van Rens
authors.forename: H O
authors.initials: HO
authors.lastname: Thijssen
authors.forename: J H
authors.initials: JH
authors.lastname: Begeer
mesh_terms: D000293:Adolescent; D000328:Adult; D001268:Atlanto-Axial Joint / Q000002:abnormalities; D001269:Atlanto-Occipital Joint / Q000002:abnormalities; D001368:Axis, Cervical Vertebra / Q000002:abnormalities*; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D004204:Joint Dislocations / Q000150:complications* / Q000601:surgery; D008297:Male; D013117:Spinal Cord Compression / Q000150:complications* / Q000628:therapy