Herpes simplex virus DNA in the brain of psychotic patients.
Herpes simplex virus (HSV) DNA was found by spot blot hybridization in the right nc. amygdalae of 3 out 10 patients who underwent curative stereotactic surgery for severe mental retardation with aggressive behavior and/or paranoic schizophrenia. Of these, 6 were also tested for the presence of CMV DNA sequences with negative results. Biopsy specimens from nc. amygdalae of another 7 psychotic patients were cultured in vitro but no virus was isolated.
Kúdelová
M
M
Institute of Virology, Slovak Academy of Sciences, Bratislava, Czechoslovakia.
Rajcáni
J
J
Pogády
J
J
Sramka
M
M
D000679:Amygdala / Q000382:microbiology*; D004279:DNA, Viral / Q000032:analysis; D006801:Humans; D009693:Nucleic Acid Hybridization; D011618:Psychotic Disorders / Q000382:microbiology*; D018139:Simplexvirus / Q000032:analysis*
D004279:DNA, Viral