GABA-immunoreactivity in ganglion cells of the rat retina.
Ganglion cells in the rat retina were labeled with the fluorescent dye, Diamidino-yellow, by retrograde transport from the superior colliculus and subsequently reacted for GABA-like immunoreactivity with a rhodamine-conjugated antiserum. Examination of sectioned retinas by fluorescence microscopy showed double labeling in approximately 6% of the ganglion cells. The presence of GABA in these neurons suggests that they may be involved in providing direct inhibitory input to the rat tectum.
Caruso
D M
DM
Department of Anatomy and Cell Biology, Wayne State University, Detroit, MI 48201.
Owczarzak
M T
MT
Goebel
D J
DJ
Hazlett
J C
JC
Pourcho
R G
RG
D000818:Animals; D007150:Immunohistochemistry; D051381:Rats; D012160:Retina / Q000378:metabolism*; D012165:Retinal Ganglion Cells / Q000378:metabolism*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D005680:gamma-Aminobutyric Acid