[Animal experiment studies of collateral reinnervation of denervated laryngeal musculature].
The course of atrophy of type I and type II muscle fibers of the posterior cricoarytenoid muscle, the lateral cricoarytenoid muscle and the medial thyroarytenoid muscle of 9 dogs have been investigated after resection of the ipsilateral recurrent laryngeal nerve after 2, 4 and 10 months. Using ATP-ase staining the histochemical results revealed a predominant atrophy of type II fibers, a reactive hypertrophy of type I fibers after a period of 4 months and a pattern of type-grouping with signs of a complete reinnervation in all laryngeal muscles within 10 months. The existence of a supplementary innervation of the intrinsic laryngeal muscles in dogs and its implication on experiments in laryngeal reinnervation are discussed.
Martin
F
F
Klinik und Poliklinik für Hals-, Nasen- und Ohrenkranke, Ludwig-Maximilians-Universität München, Klinikum Grosshadern.
D000818:Animals; D004285:Dogs; D005260:Female; D007821:Laryngeal Muscles / Q000294:innervation*; D007823:Laryngeal Nerves / Q000473:pathology*; D008854:Microscopy, Electron; D009121:Muscle Denervation; D009132:Muscles / Q000294:innervation*; D009416:Nerve Regeneration; D012009:Recurrent Laryngeal Nerve / Q000473:pathology*; D014826:Vocal Cord Paralysis / Q000473:pathology*
Tierexperimentelle Untersuchungen zur kollateralen Reinnervation der denervierten laryngealen Muskulatur.