title: [Acute manifestations in Crohn disease and ulcerative colitis. Conservative treatment of acute situations].
abstract: Ulcerative colitis (UC) and Crohn's disease (CD) can lead to perforation, abscesses and peritonitis. In such cases conservative treatment should only be secondary to surgery, whereas intensive conservative treatment is needed from the very start in toxic megacolon. The decision to operate must be made within 24-48 h. Partial or complete intestinal obstruction is frequently encountered in CD patients if the ileum is involved. Prednisone treatment can sometimes reverse this condition when combined with parenteral nutrition. Treatment of acute exacerbations of UC and CD is essentially conservative and consists of salazosulfapyridine or 5-aminosalicylic acid and prednisone.
authors.affiliation: Abteilung Gastroenterologie, Universitäts-Klinikum Essen.
authors.forename: H
authors.initials: H
authors.lastname: Goebell
mesh_terms: D000208:Acute Disease; D000636:Aminosalicylic Acids / Q000008:administration & dosage; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D003131:Combined Modality Therapy; D003424:Crohn Disease / Q000188:drug therapy*; D006801:Humans; D019804:Mesalamine; D010288:Parenteral Nutrition; D011241:Prednisone / Q000008:administration & dosage; D011446:Prospective Studies; D012460:Sulfasalazine / Q000008:administration & dosage
chemical_list: D000636:Aminosalicylic Acids; D012460:Sulfasalazine; D019804:Mesalamine; D011241:Prednisone
vernacular_title: Akute Manifestationen bei Morbus Crohn und Colitis ulcerosa. Konservative Behandlung akuter Situationen.