[Fetal death caused by myocarditis and isolated congenital auriculoventricular block].
A 26-year old woman gave birth, at term, to a child with isolated complete heart block. A second pregnancy was interrupted by foetal death. Among other immunological abnormalities, this young woman had an antibody resembling the anti-SS-B antibody. At pathological examination the foetus' heart was found to be free of malformation but presented with subacute myocarditis associated with microcalcifications of the conductive tissue. Such findings suggest that an incipient myocarditis may either result in foetal death or lead to fibrosis of conduction pathways with isolated complete heart block.
Herreman
G
G
Ferme
I
I
Morel
S
S
Batisse
J
J
Vuon
N P
NP
Meyer
O
O
D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis*; D005260:Female; D005313:Fetal Death / Q000209:etiology*; D005315:Fetal Diseases / Q000276:immunology*; D006327:Heart Block / Q000151:congenital* / Q000209:etiology / Q000473:pathology; D006801:Humans; D008297:Male; D009205:Myocarditis / Q000209:etiology* / Q000276:immunology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology*
D000974:Antibodies, Antinuclear; C035357:SS-B antibodies
Mort foetale par myocardite et bloc auriculo-ventriculaire congénital isolé.