Specificity of esterases and structure of prodrug esters. II. Hydrolytic regeneration behavior of 5-fluoro-2'-deoxyuridine (FUdR) from 3',5'-diesters of FUdR with rat tissue homogenates and plasma in relation to their antitumor activity.
Kawaguchi
T
T
Saito
M
M
Suzuki
Y
Y
Nambu
N
N
Nagai
T
T
D000818:Animals; D004950:Esterases / Q000378:metabolism; D005467:Floxuridine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D006868:Hydrolysis; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D051381:Rats; D011919:Rats, Inbred Strains; D014018:Tissue Distribution
D005467:Floxuridine; D004950:Esterases