title: Simultaneous occurrence of medullary and follicular carcinoma in the same thyroid lobe.
abstract: A rare case of the simultaneous development of medullary and follicular carcinoma of the thyroid gland in a 51-year-old Japanese woman is examined. A preoperative diagnosis was made by needle aspiration cytology. Neoplastic cells of the medullary carcinoma were positive for calcitonin and carcinoembryonic antigen, whereas the tumor cells of the follicular carcinoma were negative for these substances. This case presents evidence that, in rare cases, two malignant epithelial neoplasms of different origins can occur in the same lobe of the thyroid.
authors.affiliation: First Department of Pathology, Gifu University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Tanaka
authors.forename: N
authors.initials: N
authors.lastname: Yoshimi
authors.forename: N
authors.initials: N
authors.lastname: Kanai
authors.forename: H
authors.initials: H
authors.lastname: Mori
authors.forename: K
authors.initials: K
authors.lastname: Nagai
authors.forename: A
authors.initials: A
authors.lastname: Fujii
authors.forename: S
authors.initials: S
authors.lastname: Sakata
authors.forename: N
authors.initials: N
authors.lastname: Tokimitsu
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology; D002277:Carcinoma / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000473:pathology