title: Resectional surgical procedures for carcinoma of the head of the pancreas.
abstract: Of a total series of 103 patients with preoperatively diagnosed carcinoma of the head of the pancreas (including ampullary carcinoma, carcinoma of the distal part of the common bile duct and pancreatic duct and acinar cell carcinoma), 78 underwent pancreatic resection. The remaining 25 had palliative surgical treatment, either a gastric or biliary bypass, and are not included in the present study. Three of the 78 patients who underwent pancreatic resection died, and ten patients required early reoperation. Predictive criteria could be formulated for the prognosis and outcome of the patients with carcinoma of the head of the pancreas. The most reliable index for survival time of the patients proved to be the radicality of the resection, which was directly related to the differentiation of the primary tumor. Forty-three of 48 patients who underwent radical resection are alive, with a survival time ranging from three to 49 months. Eleven of 23 patients who underwent palliative resection are alive, with a survival time ranging from two to 29 months. Of 44 patients with well or moderately differentiated adenocarcinoma who underwent radical resection, 38 are alive, with a survival time ranging from six to 41 months (mean of 29 months).
authors.affiliation: Department of Surgery, University of Amsterdam, The Netherlands.
authors.forename: N J
authors.initials: NJ
authors.lastname: Lygidakis
authors.forename: M N
authors.initials: MN
authors.lastname: van der Hyde
authors.forename: H J
authors.initials: HJ
authors.lastname: Houthoff
authors.forename: M E
authors.initials: ME
authors.lastname: Schipper
authors.forename: K
authors.initials: K
authors.lastname: Huibregtse
authors.forename: G N
authors.initials: GN
authors.lastname: Tytgat
authors.forename: M J
authors.initials: MJ
authors.lastname: Lubber
authors.forename: J W
authors.initials: JW
authors.lastname: Reeders
authors.forename: M M
authors.initials: MM
authors.lastname: Bosey
authors.forename: J
authors.initials: J
authors.lastname: Oosting
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery; D000368:Aged; D002276:Carcinoid Tumor / Q000401:mortality / Q000473:pathology / Q000601:surgery; D002277:Carcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010180:Pancreatectomy / Q000379:methods; D010190:Pancreatic Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D011379:Prognosis; D012086:Reoperation