title: Early evaluation and therapy for caustic esophageal injury.
abstract: Forty-one patients with caustic ingestion were reviewed. Eighty-three percent were children, all of whom suffered accidental injury. Liquid drain cleaner was the agent in 57 percent and was responsible for all esophageal burns. Symptoms and physical findings were unreliable in predicting the extent of injury. Endoscopy was performed in most patients within 36 hours of ingestion and accurately estimated the risk of subsequent esophageal stricture formation. Steroid administration had no influence on the development of strictures. Esophageal strictures developed in 22 percent of the patients. One-third were successfully managed by periodic dilation, whereas the remaining two-thirds required esophagectomy and reconstruction. Early endoscopic evaluation was the best means of assessing the degree of injury after caustic ingestion. Routine steroid administration had no apparent clinical benefit.
authors.affiliation: Department of Surgery, University of Chicago Medical Center, Illinois 60637.
authors.forename: M K
authors.initials: MK
authors.lastname: Ferguson
authors.forename: M
authors.initials: M
authors.lastname: Migliore
authors.forename: V M
authors.initials: VM
authors.lastname: Staszak
authors.forename: A G
authors.initials: AG
authors.lastname: Little
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002057:Burns, Chemical / Q000145:classification / Q000209:etiology / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D004947:Esophagus / Q000293:injuries*; D005260:Female; D006795:Household Products / Q000009:adverse effects; D006801:Humans; D007223:Infant; D007830:Larynx / Q000293:injuries; D008297:Male; D008875:Middle Aged; D010614:Pharynx / Q000293:injuries; D013256:Steroids / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D013256:Steroids