title: Population genetics of the globin genes in Polynesians.
abstract: Globin gene mapping data enable Polynesians to be divided into three distinct groups: (i) Maoris, Cook Islanders, (ii) Tongans, Samoans, (iii) Niue Islanders. Unusual RFLPs detected by the restriction enzymes Apa I and Bgl II are found in Polynesians. A high frequency of alpha-thalassemia in this population is explained by genetic drift and a founder effect.
authors.affiliation: Molecular Biology Laboratory, University of Sydney, NSW, Australia.
authors.forename: R J
authors.initials: RJ
authors.lastname: Trent
authors.forename: K N
authors.initials: KN
authors.lastname: Mickleson
authors.forename: J
authors.initials: J
authors.lastname: Yakas
authors.forename: M
authors.initials: M
authors.lastname: Hertzberg
mesh_terms: D005787:Gene Frequency; D015321:Gene Rearrangement; D005914:Globins / Q000235:genetics*; D006801:Humans; D008403:Mass Screening; D012150:Polymorphism, Restriction Fragment Length; D011114:Polynesia
chemical_list: D005914:Globins