title: Extra-adrenal myelolipoma.
abstract: Extra-adrenal myelolipomas are rarely reported lesions, with only 18 cases found in the world literature. We report a series of three cases, all occurring in women in an age range of 68 to 83 years (mean, 77 years). One patient presented with a pelvic mass while the other two cases were incidental findings at autopsy. All lesions were presacral in location, encapsulated, and not attached to adjacent structures. Sizes ranged from 6 to 12 cm in greatest dimension and from 72 to 330 g. Color was a variegated yellow to red-brown. Microscopically, all were composed of mature fat and focal collections of normal hematopoietic elements. The nature of these lesions is not known but most authors favor a choristomatous origin. They must be distinguished from extramedullary hematopoietic tumors seen in patients with severe anemias, myeloproliferative disorders, and skeletal disease.
authors.affiliation: Department of Pathology, M.D. Anderson Hospital and Tumor Institute, Houston.
authors.forename: D J
authors.initials: DJ
authors.lastname: Grignon
authors.forename: M J
authors.initials: MJ
authors.lastname: Shkrum
authors.forename: M S
authors.initials: MS
authors.lastname: Smout
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008067:Lipoma / Q000473:pathology*; D010386:Pelvic Neoplasms / Q000473:pathology*; D012186:Retroperitoneal Neoplasms / Q000473:pathology*