Polymorphism of the complement C3 gene in the Lebanese population.
The C3 protein polymorphism was studied in 300 unrelated Lebanese. The gene frequencies were calculated and compared with other populations. DNA samples digested with various endonucleases were hybridized with a C3 probe, which was found to detect a frequent Sac I restriction fragment length polymorphism (RFLP) and a less frequent Taq I RFLP in the Lebanese population, as well as in the French populations.
Ghanem
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Laboratoire d'Immunogénétique, UA CNRS 1191, Génétique Moléculaire, Université des Sciences et Techniques du Languedoc, Montpellier, France.
Lefranc
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MP
Lefranc
G
G
D000483:Alleles; D003176:Complement C3 / Q000235:genetics*; D015252:Deoxyribonucleases, Type II Site-Specific; D005787:Gene Frequency; D006801:Humans; D007861:Lebanon; D012150:Polymorphism, Restriction Fragment Length
D003176:Complement C3; C024408:endodeoxyribonuclease SacI; D015252:Deoxyribonucleases, Type II Site-Specific; C027046:TCGA-specific type II deoxyribonucleases