title: Brain-stem auditory evoked potential abnormalities with unilateral brain-stem lesions demonstrated by magnetic resonance imaging.
abstract: We correlated the brain-stem auditory evoked potential (BAEP) abnormalities in 24 patients with discrete unilateral brain-stem lesions demonstrated by magnetic resonance imaging. In 18 patients who had BAEP abnormalities either confined to or more severe on stimulation of one ear, the lesion on magnetic resonance imaging was in the brain stem ipsilateral to the corresponding ear. Mesencephalic lesions produced amplitude abnormalities of the IV/V complex while pontine lesions resulted in abnormalities of earlier components (wave II and/or III). Prolongation of the I-III interpeak latency tended to occur with pontine lesions and of the III-V interpeak latency with mesencephalic lesions. Unilateral brain-stem lesions, particularly at the mesencephalic level, often produced BAEP abnormalities on both ipsilateral and contralateral monaural stimulation.
authors.affiliation: Department of Neurology, Indiana University School of Medicine, Indianapolis.
authors.forename: O N
authors.initials: ON
authors.lastname: Markand
authors.forename: M R
authors.initials: MR
authors.lastname: Farlow
authors.forename: J C
authors.initials: JC
authors.lastname: Stevens
authors.forename: M K
authors.initials: MK
authors.lastname: Edwards
mesh_terms: D000328:Adult; D000368:Aged; D001927:Brain Diseases / Q000175:diagnosis* / Q000503:physiopathology; D001933:Brain Stem / Q000503:physiopathology; D005072:Evoked Potentials, Auditory; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged