Scanning tunneling microscopy of uncoated recA-DNA complexes.
Uncoated recA-DNA complexes were imaged with the scanning tunneling microscope (STM). The images, which reveal the right-handed helical structure of the complexes with subunits clearly resolved, are comparable in quality to STM images of metal-coated specimens. Possible conduction mechanisms that allow STM imaging of biological macromolecules are discussed.
Amrein
M
M
Institute of Cell Biology, Swiss Federal Institute of Technology, Zurich, Switzerland.
Dürr
R
R
Stasiak
A
A
Gross
H
H
Travaglini
G
G
D000085:Acetates; D019342:Acetic Acid; D000327:Adsorption; D000538:Aluminum Silicates; D004247:DNA / Q000378:metabolism*; D004563:Electrochemistry; D046911:Macromolecular Substances; D008274:Magnesium; D015636:Magnesium Chloride; D008854:Microscopy, Electron; D015394:Molecular Structure; D011487:Protein Conformation; D011938:Rec A Recombinases / Q000378:metabolism*
D000085:Acetates; D000538:Aluminum Silicates; D046911:Macromolecular Substances; D015636:Magnesium Chloride; D004247:DNA; D011938:Rec A Recombinases; D008274:Magnesium; D019342:Acetic Acid; C011934:mica