title: Gadolinium-DTPA enhanced MR imaging of spinal dural arteriovenous fistulas.
abstract: To evaluate the role of magnetic resonance (MR) in the diagnosis of dural arteriovenous (AV) fistulas and the resulting myelopathy, the MR examinations of 11 patients with symptoms and signs of slowly progressive myelopathy of the lower spinal cord have been reviewed. Patients with intradural or extradural AV malformations were excluded. Six patients have been examined without the use of a contrast agent. The other five patients were studied prior and after intravenous administration of gadolinium-diethylenetriamine pentaacetic acid (DTPA). Serpentine linear areas of low signal due to flow void effects within the subdural space have been detected in seven patients. The T1-weighted sagittal images and T2-weighted sagittal and axial images demonstrated signal intensity changes within the center of the cord due to prolongation of T1 and T2 relaxation times. In addition, a relatively abrupt increase of the sagittal and transverse diameters of the lower thoracic cord was found in all cases. In nine patients T1-weighted, proton-density and T2-weighted sagittal images presented "blurred" margins of the lower thoracic cord. After intravenous administration of Gd-DTPA (0.1 mmol/kg), contrast enhancement was present not only within these vessels but also within the lower spinal cord. There was only slight enhancement of the cord immediately after injection of the contrast agent, but significant enhancement was observed 40-45 min later.
authors.affiliation: Radiological Institute, Oldenburg, F.R.G.
authors.forename: B
authors.initials: B
authors.lastname: Terwey
authors.forename: H
authors.initials: H
authors.lastname: Becker
authors.forename: A K
authors.initials: AK
authors.lastname: Thron
authors.forename: G
authors.initials: G
authors.lastname: Vahldiek
mesh_terms: D000328:Adult; D000368:Aged; D000792:Angiography; D001099:Arachnoid / Q000473:pathology; D001164:Arteriovenous Fistula / Q000175:diagnosis*; D003287:Contrast Media; D004388:Dura Mater / Q000098:blood supply / Q000473:pathology*; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009192:Myelography; D009942:Organometallic Compounds; D004369:Pentetic Acid; D013118:Spinal Cord Diseases / Q000175:diagnosis*
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA