title: Circulating levels of biotin in the fowl (Gallus domesticus): modulation by oestrogen.
abstract: 1. Exogenous oestrogen administration to immature male and female chickens significantly increased plasma biotin and significantly reduced liver biotin concentrations. 2. The elevation in plasma biotin concentrations was dose dependent and maximum values were observed 48 hr after a single injection of oestrogen. 3. A second oestrogen injection significantly increased plasma biotin concentrations compared with values obtained after the initial injection given 10 days previously. 4. Plasma biotin concentrations were significantly increased in female, but not male, birds approaching sexual maturity. This increase coincided with the time of the known surge in endogenous oestrogen production by the developing ovary.
authors.affiliation: Department of Animal Husbandry, University of Sydney, Camden, NSW, Australia.
authors.forename: W L
authors.initials: WL
authors.lastname: Bryden
mesh_terms: D000818:Animals; D001710:Biotin / Q000097:blood / Q000378:metabolism*; D004958:Estradiol / Q000502:physiology*; D005260:Female; D008099:Liver / Q000033:anatomy & histology / Q000378:metabolism; D008297:Male; D009929:Organ Size; D011200:Poultry / Q000378:metabolism / Q000502:physiology*; D012737:Sex Factors
chemical_list: D004958:Estradiol; D001710:Biotin