Ecdysone catabolism in the white mouse.
Ecdysone metabolism was investigated in the white mouse Mus musculus. It was shown to involve dehydroxylation at C-14, followed by reduction of ring B into a 6 alpha-hydroxy derivative and epimerization at C-3.
Girault
J P
JP
Université René Descartes, Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, CNRS U.A. 400, Paris, France.
Lafont
R
R
Kerb
U
U
D000818:Animals; D001711:Biotransformation; D002851:Chromatography, High Pressure Liquid; D004440:Ecdysone / Q000378:metabolism*; D008297:Male; D051379:Mice; D015394:Molecular Structure; D010084:Oxidation-Reduction
D004440:Ecdysone