title: Ptosis and supranuclear downgaze paralysis.
abstract: A patient developed the unusual combination of a supranuclear downward gaze paralysis and bilateral ptosis. It was caused by a single midbrain glioma. Other ocular motor functions were intact. The neuropathologic examination showed a tumor growing mainly around the third ventricle and the aqueduct. The findings agree with recent experimental evidence that a network of neural elements involved in eyelid control lies in the supraoculomotor area immediately dorsal to the oculomotor nucleus.
authors.affiliation: Institute of Neuropathology, Ludwig Maximilian University of Munich, FRG.
authors.forename: J A
authors.initials: JA
authors.lastname: Büttner-Ennever
authors.forename: J F
authors.initials: JF
authors.lastname: Acheson
authors.forename: U
authors.initials: U
authors.lastname: Büttner
authors.forename: E M
authors.initials: EM
authors.lastname: Graham
authors.forename: T J
authors.initials: TJ
authors.lastname: Leonard
authors.forename: M D
authors.initials: MD
authors.lastname: Sanders
authors.forename: R R
authors.initials: RR
authors.lastname: Russell
mesh_terms: D000368:Aged; D001254:Astrocytoma / Q000150:complications / Q000473:pathology; D001763:Blepharoptosis / Q000150:complications* / Q000209:etiology / Q000473:pathology; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology; D005133:Eye Movements; D005260:Female; D005403:Fixation, Ocular; D006801:Humans; D009801:Oculomotor Muscles / Q000473:pathology; D010243:Paralysis / Q000150:complications* / Q000209:etiology / Q000473:pathology