Measurement of cerebrospinal fluid movement in the spine. An experimental technique.
The authors devised a new technique for measuring cerebrospinal fluid movement in the spine. With gated list mode acquisition of radioactive emissions, bulk flow, oscillations, and dispersion of a bolus of isotope can be measured. The accuracy of the technique was measured in a simulation in which fluid oscillated at 71 cycles/minute and displaced at 6.5 cm/minute. With this method, the measured oscillation frequency and amplitude and the rate of translation were within 10% of actual values.
Palmer
D W
DW
Department of Radiology, Medical College of Wisconsin, Milwaukee 53226.
Haughton
V M
VM
Nguyen
C M
CM
Palmer
S R
SR
D002555:Cerebrospinal Fluid / Q000502:physiology*; D006801:Humans; D007700:Kinetics; D008953:Models, Anatomic; D011877:Radionuclide Imaging; D013131:Spine / Q000000981:diagnostic imaging*