Immuohistochemical demonstration of alpha-atrial natriretic plypeptide-containing neurons in the rat brain.
Using the immunoperoxidase technique in conjunction with specific antisera to alpha-atrial natriuretic polypeptide (alpha-ANP), it was shown that immunoreactive cell bodies and varicose fibers are widely distributed throughout the rat brain. The highest concentrations of alpha-ANP-containing neuronal cell bodies and fibers were found in the hypothalamus and septum. This result confirms the radioimmunological determination of alpha-ANP immunoreactivity in the rat brain.
Kawata
M
M
Ueda
S
S
Nakao
K
K
Morii
N
N
Kiso
Y
Y
Imura
H
H
Sano
Y
Y
D000818:Animals; D009320:Atrial Natriuretic Factor / Q000378:metabolism*; D001921:Brain / Q000378:metabolism*; D006651:Histocytochemistry; D007124:Immunoenzyme Techniques; D008297:Male; D051379:Mice; D009474:Neurons / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D014018:Tissue Distribution
D009320:Atrial Natriuretic Factor