title: Cyclin/PCNA is a cell cycle modulated nuclear protein with a role in DNA replication.
abstract: Cyclin/PCNA (auxiliary protein of DNA polymerase delta) is a proliferation sensitive DNA replication protein whose synthesis is modulated during the cell cycle. All available information suggests that cyclin/PCNA may trigger DNA replication following the formation of pre-replicative complexes at the G1/S transition border.
authors.affiliation: Department of Medical Biochemistry, Aarhus University, Denmark.
authors.forename: J E
authors.initials: JE
authors.lastname: Celis
authors.forename: P
authors.initials: P
authors.lastname: Madsen
authors.forename: H V
authors.initials: HV
authors.lastname: Nielsen
authors.forename: B
authors.initials: B
authors.lastname: Gesser
authors.forename: H H
authors.initials: HH
authors.lastname: Rasmussen
authors.forename: D
authors.initials: D
authors.lastname: Cruger
mesh_terms: D002478:Cells, Cultured; D004261:DNA Replication; D005347:Fibroblasts / Q000378:metabolism; D006801:Humans; D007399:Interphase; D009687:Nuclear Proteins / Q000096:biosynthesis*; D018809:Proliferating Cell Nuclear Antigen
chemical_list: D009687:Nuclear Proteins; D018809:Proliferating Cell Nuclear Antigen