Induction of a 70,000 dalton protein in hypertrophic rat heart.
Two-dimensional gel electrophoresis analysis of the product of in vitro translation of polyadenylated RNAs extracted from rat heart rendered hypertrophic by aortic constriction, shows a new protein species not present in the map of control hearts. The same is also obtained when hypertrophy is induced by treatment with thyroxine.
Davalli
P
P
Ferrari
S
S
Corti
A
A
D000818:Animals; D001011:Aorta / Q000502:physiology; D006332:Cardiomegaly / Q000209:etiology / Q000378:metabolism*; D003250:Constriction; D004591:Electrophoresis, Polyacrylamide Gel; D007525:Isoelectric Focusing; D008297:Male; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013974:Thyroxine
D012333:RNA, Messenger; D013974:Thyroxine