title: [Amprolium residues in eggs following administration of amprolium/ethopabate in laying hens and breeding hens].
abstract: Amprolium may be used as a coccidiostat in rearing hens and is a therapeutical agent used in laying hens. As a result of cross contamination, low amprolium levels may occur in feed. Feed containing a concentration of amprolium ranging from 5 to 250 mg/kg was therefore supplied to groups of laying hens. The amprolium residues in the yolks during and after treatment were subsequently determined. These levels varied from 1.75 mg/kg in the group fed 250 mg/kg to 0.2 mg/kg in the group fed 5 mg/kg. Amprolium levels in the whites of eggs were much lower than those in the yolks. The residues in yolks decreased below detectable levels (less than 0.005 mg/kg) within approximately ten days after treatment. Rearing hens in a tiered wire floor system were given amprolium in their feed until the first egg was laid. Amprolium residues in yolks were detected for well over a fortnight after the onset of laying. The amprolium residues determined in yolk did not exceed US tolerance levels of 8 mg/kg.
authors.affiliation: Centrum voor Onderzoek en Voorlichting voor de Pluimveehouderij, Het Spelderholt, Beekbergen.
authors.forename: C A
authors.initials: CA
authors.lastname: Kan
authors.forename: W
authors.initials: W
authors.lastname: van Leeuwen
authors.forename: H W
authors.initials: HW
authors.lastname: van Gend
mesh_terms: D000670:Amprolium / Q000008:administration & dosage / Q000032:analysis*; D000818:Animals; D002645:Chickens; D003049:Coccidiostats / Q000032:analysis*; D004350:Drug Residues / Q000032:analysis*; D004529:Egg White / Q000032:analysis; D004530:Egg Yolk / Q000032:analysis; D004531:Eggs / Q000032:analysis*; D005011:Ethopabate / Q000008:administration & dosage; D010847:Picolines / Q000031:analogs & derivatives*; D011201:Poultry Diseases / Q000517:prevention & control
chemical_list: D003049:Coccidiostats; D010847:Picolines; D005011:Ethopabate; D000670:Amprolium
vernacular_title: Residuen van amprolium in eieren na toediening van amprolium/ethopabaat aan leghennen en opfokleghennen.