title: Adenosine deaminase containing fiber pathway from the superior colliculus to the lateral posterior nucleus of the rat.
abstract: Presence of a projection containing adenosine deaminase (ADA)-like immunoreactivity from the stratum opticum (SO) to the dorsomedial portion of the lateral posterior nucleus of the thalamus (LPN) of the rat was demonstrated using a method combining retrograde tracing by horseradish peroxidase (HRP) and immunohistochemistry for ADA. In the caudal two thirds of the LPN, a clearly delimited ADA-like immunoreactive fiber plexus was located. Injection of HRP into the lateral posterior nucleus labeled many neurons in the medial portion of the SO where medium-sized neurons with ADA immunoreactivity were concentrated. Simultaneous immunostaining showed that some of the HRP-labeled neurons are ADA-positive.
authors.affiliation: Department of Anatomy, Osaka University Medical School, Japan.
authors.forename: J J
authors.initials: JJ
authors.lastname: Miguel-Hidalgo
authors.forename: E
authors.initials: E
authors.lastname: Senba
authors.forename: S
authors.initials: S
authors.lastname: Matsutani
authors.forename: K
authors.initials: K
authors.lastname: Takatsuji
authors.forename: M
authors.initials: M
authors.lastname: Tohyama
mesh_terms: D000243:Adenosine Deaminase / Q000378:metabolism*; D000818:Animals; D007150:Immunohistochemistry; D008297:Male; D009700:Nucleoside Deaminases / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013477:Superior Colliculi / Q000166:cytology / Q000201:enzymology*; D013787:Thalamic Nuclei / Q000166:cytology / Q000201:enzymology*
chemical_list: D009700:Nucleoside Deaminases; D000243:Adenosine Deaminase