Pure mesangial proliferative glomerulonephritis. A clinicomorphologic analysis and its possible role in morphologic transition of minimal change lesion.
Renal biopsies from 45 children with idiopathic nephrotic syndrome were analysed. A clinicopathologic correlation has been attempted in 19 children with mesangioproliferative glomerulonephritis. Mesangial hypercellularity is found to have a direct correlation with the clinical presentation, response to therapy and final outcome. The presence of diffuse mesangial IgM or IgM with C3 is of no significance and lacks specificity.
Andal
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A
Department of Paediatrics, ICMR, Safdarjang Hospital, New Delhi, India.
Saxena
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Chellani
H K
HK
Sharma
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S
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D015432:Glomerulonephritis, Membranoproliferative / Q000150:complications / Q000276:immunology / Q000473:pathology*; D005923:Glomerulosclerosis, Focal Segmental / Q000209:etiology / Q000473:pathology; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D007223:Infant; D007668:Kidney / Q000276:immunology / Q000473:pathology; D009402:Nephrosis, Lipoid / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D011241:Prednisone / Q000627:therapeutic use
D007075:Immunoglobulin M; D011241:Prednisone