Preliminary findings on calmodulin-stimulated Ca2+-ATPase of erythrocyte ghosts in psychotic patients.
Kinetic properties of the calmodulin-stimulated erythrocyte ghost Ca2+-ATPase seem to be altered in some sub-groups of affective and schizophrenic psychoses. The sub-group of affective disorders concerned mostly unipolar manic and bipolar psychoses with predominantly manic episodes. In the corresponding cases from schizophrenics hyper- and parakinetic basic syndromes were predominantly diagnosed. An evaluation of our preliminary results was undertaken in connection with our biochemical hypothesis on possible alterations in the regulation of Ca2+ concentrations and Ca2+-calmodulin-mediated processes under certain psychotic conditions.
Kluge
H
H
Kühne
G E
GE
D001714:Bipolar Disorder / Q000201:enzymology; D002118:Calcium / Q000097:blood; D000252:Calcium-Transporting ATPases / Q000097:blood*; D002147:Calmodulin / Q000097:blood*; D003866:Depressive Disorder / Q000201:enzymology; D004910:Erythrocyte Membrane / Q000201:enzymology*; D006801:Humans; D007700:Kinetics; D011618:Psychotic Disorders / Q000201:enzymology*; D012559:Schizophrenia / Q000201:enzymology
D002147:Calmodulin; D000252:Calcium-Transporting ATPases; D002118:Calcium