Infantile autism, fragile (X) (q27.3) and RFLP analysis in an extended Swedish family.
In an extended family with eight individuals with infantile autism, in association with other developmental disorders and fragile (X) (q27.3), DNA techniques were used to investigate linkage between X chromosomal probes and the disorder. F9 was not informative and recombination was found between fragile X and DXS15, DXS51 and DXS52.
Anvret
M
M
Department of Clinical Genetics, Karolinska Sjukhuset, Stockholm, Sweden.
Gillberg
C
C
Wahlström
J
J
Albertsson-Wikland
K
K
Davies
K
K
D000293:Adolescent; D000328:Adult; D001321:Autistic Disorder / Q000235:genetics*; D015139:Blotting, Southern; D002648:Child; D003001:Cloning, Molecular; D015342:DNA Probes; D005260:Female; D005600:Fragile X Syndrome / Q000235:genetics*; D005787:Gene Frequency; D008040:Genetic Linkage; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D012150:Polymorphism, Restriction Fragment Length; D012729:Sex Chromosome Aberrations / Q000235:genetics*; D013548:Sweden
D015342:DNA Probes