title: Relative importance of estrogen and progesterone receptor assays as prognostic indicators in primary breast cancer: a short-term study.
abstract: This short-term study of the relative importance of estrogen and progesterone receptors shows that progesterone receptor correlates better than estrogen receptor with tumor recurrence regardless of lymph-node status. Life-table analysis has effectively identified only two groups of patients that may be classified by progesterone receptor status alone. Progesterone-receptor negativity correlated well with tumors of histological Grade III; estrogen-receptor positivity correlated with Grade I and II tumors. The earlier recurrence of Grade III breast tumors may explain why progesterone receptor is a better prognostic indicator than estrogen receptor in short-term studies.
authors.affiliation: Department of Clinical Chemistry, Doncaster Royal Infirmary, U.K.
authors.forename: D
authors.initials: D
authors.lastname: Brocklehurst
authors.forename: C E
authors.initials: CE
authors.lastname: Wilde
authors.forename: J A
authors.initials: JA
authors.lastname: Finbow
authors.forename: R
authors.initials: R
authors.lastname: Brett
authors.forename: A E
authors.initials: AE
authors.lastname: Champion
authors.forename: D G
authors.initials: DG
authors.lastname: Dewhurst
mesh_terms: D001943:Breast Neoplasms / Q000032:analysis* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008593:Menopause; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis*; D011379:Prognosis; D011960:Receptors, Estrogen / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis*
chemical_list: D011960:Receptors, Estrogen; D011980:Receptors, Progesterone