Prognostic value of serum phospholipase A in the multitraumatized patient.
Phospholipase A serum activity was prospectively studied in 39 patients with multiple trauma. There was no correlation of phospholipase A activity with type or severity of injury. With increasing phospholipase A levels, a rise in mortality was found. A prediction of fatal outcome on an individual basis was not possible. The sensitivity for complications was 90%, whereas the predictive value of the positive test (64%) and specificity (47%) were low. When the behavior of phospholipase A and elastase release were compared, no correlation between these two parameters could be detected. Therefore, PMN leukocytes do not seem to be a major source of phospholipase A in serum.
Waydhas
C
C
Chirurgische Klinik Innenstadt, Universität München.
Nast-Kolb
D
D
Duswald
K H
KH
Lehnert
P
P
Schweiberer
L
L
D058186:Acute Kidney Injury / Q000201:enzymology; D000293:Adolescent; D000328:Adult; D000368:Aged; D006801:Humans; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000201:enzymology; D009104:Multiple Trauma / Q000201:enzymology*; D009504:Neutrophils / Q000201:enzymology; D010196:Pancreatic Elastase / Q000097:blood; D010740:Phospholipases / Q000097:blood*; D010741:Phospholipases A / Q000097:blood*; D011379:Prognosis; D012128:Respiratory Distress Syndrome / Q000201:enzymology
D010740:Phospholipases; D010741:Phospholipases A; D010196:Pancreatic Elastase