title: [Cibalen poisoning in an infant].
abstract: A toxicological investigation of urine could finally explain abnormal neurological symptoms with apnea. 2 Cibalen-suppositories for children were given to an 7 week old infant as treatment of an upper respiratory infect. 12 hours were between the application of the 2 suppositories. 2 hours after the second application coma, hypertonus, opisthotonus, miosis and depression of ventilation were found. 10 hours later an apnea occurred. These symptoms were due to the synergistic effect of Phenobarbital, Aminophenazon and Codeinphosphat in an overhigh dose.
authors.affiliation: Kinderspital Salzburg.
authors.forename: J
authors.initials: J
authors.lastname: Riedler
mesh_terms: D000632:Aminopyrine / Q000008:administration & dosage / Q000009:adverse effects / Q000506:poisoning*; D001463:Barbiturates / Q000008:administration & dosage / Q000009:adverse effects / Q000506:poisoning*; D003061:Codeine / Q000008:administration & dosage / Q000009:adverse effects / Q000506:poisoning*; D004158:Diphenylacetic Acids / Q000009:adverse effects / Q000506:poisoning*; D004338:Drug Combinations / Q000009:adverse effects / Q000506:poisoning; D006801:Humans; D007223:Infant; D008297:Male; D012131:Respiratory Insufficiency / Q000139:chemically induced*; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D013488:Suppositories
chemical_list: D001463:Barbiturates; D004158:Diphenylacetic Acids; D004338:Drug Combinations; D013488:Suppositories; C092752:spasmoplus; D000632:Aminopyrine; D003061:Codeine
vernacular_title: Cibalen-Intoxikation bei einem Säugling.