Intraoperative irradiation of 16 spontaneously occurring canine neoplasms.
Sixteen dogs with malignant neoplasms were treated with intraoperative radiation therapy after surgical debulking. Fractionated external beam radiation therapy was given postoperatively to 11 dogs. Healing of surgical incisions was uncomplicated in 14 dogs. When the ureters or urinary bladder were included in the irradiation field, they became stenotic and fibrotic. Urinary incontinence and secondary renal injury were common. Local tumor control was poor regardless of site or tumor type.
Withrow
S J
SJ
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523.
Gillette
E L
EL
Hoopes
P J
PJ
McChesney
S L
SL
D000818:Animals; D002295:Carcinoma, Transitional Cell / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*; D003131:Combined Modality Therapy; D004283:Dog Diseases / Q000532:radiotherapy* / Q000601:surgery; D004285:Dogs; D005260:Female; D007430:Intraoperative Care; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000662:veterinary; D009369:Neoplasms / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*; D012888:Skull Neoplasms / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary; D014513:Ureter / Q000528:radiation effects; D014523:Urethral Neoplasms / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*; D001743:Urinary Bladder / Q000528:radiation effects; D001749:Urinary Bladder Neoplasms / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*; D014945:Wound Healing