[Effects of repeated acupuncture action on pain sensitivity and beta-endorphin contents of the hypothalamus and midbrain of the rat].
Changes in latencies (L) of nociceptive (NC) reactions of hot plate (HP) tail flick (TF) tests and dynamics of beta-endorphin (beta-ED) in hypothalamus and midbrain were studied in albino rats receiving 15 sessions of acupuncture (A) (20 min daily in bilateral Ho-Ku). It was shown that repeated A facilitated prolongation of LHP and LTF as compared to baseline and control levels. A decrease of the anti-NC systems capacity for activation in response to each A stimulation was observed. The dynamics of beta-endorphin in hypothalamus showed an opposite tendency as compared to that in midbrain. It is suggested that such a correlation of beta-ED activities in midbrain and hypothalamus might be one of the reasons for anti-NC mechanisms adaptation to A.
Bragin
E O
EO
Popkova
E V
EV
Vasilenko
G F
GF
D015670:Acupuncture Therapy; D000818:Animals; D004723:Endorphins / Q000032:analysis* / Q000502:physiology; D007031:Hypothalamus / Q000032:analysis*; D008636:Mesencephalon / Q000032:analysis*; D010146:Pain / Q000503:physiopathology*; D010147:Pain Measurement; D051381:Rats
D004723:Endorphins
Vliianie mnogokratnogo akupunkturnogo vozdeĭstviia na bolevuiu chuvstvitel'nost' i soderzhanie beta-éndorfina v gipotalamuse i srednem mozge krys.