title: The ultrastructure of somatostatin-immunoreactive cell bodies, nerve fibers and terminals in the dorsal horn of rat spinal cord.
abstract: The distribution and ultrastructure of somatostatin-immunoreactive neurons, nerve fibers and axon terminals in the dorsal horn of rat thoracic spinal cord were studied by immunohistochemistry at both the light and electron microscopic levels. Somatostatin-immuno reactive neurons were predominantly observed in Rexed laminae I and II of the dorsal horn of spinal cord. Somatostatin-immunoreactive electron dense peroxidase material was concentrated in the Golgi apparatus and rough endoplasmic reticulum of the somatostatin-immunoreactive neurons, and was characteristically sparse in other regions of the cytoplasm. In the somatostatin-immunoreactive fibers and terminals, immunoreactive electron dense material was concentrated in the microtubules and large synaptic vesicles.
authors.affiliation: Department of Anatomy, Okayama University Medical School, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Mizukawa
authors.forename: N
authors.initials: N
authors.lastname: Otsuka
authors.forename: P L
authors.initials: PL
authors.lastname: McGeer
authors.forename: S R
authors.initials: SR
authors.lastname: Vincent
authors.forename: E G
authors.initials: EG
authors.lastname: McGeer
mesh_terms: D000818:Animals; D001369:Axons / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D006056:Golgi Apparatus / Q000648:ultrastructure; D007124:Immunoenzyme Techniques; D008297:Male; D008854:Microscopy, Electron; D009411:Nerve Endings / Q000648:ultrastructure*; D009412:Nerve Fibers / Q000648:ultrastructure*; D009474:Neurons / Q000648:ultrastructure*; D051381:Rats; D011919:Rats, Inbred Strains; D013004:Somatostatin / Q000032:analysis*; D013116:Spinal Cord / Q000648:ultrastructure*
chemical_list: D013004:Somatostatin