Chronic basal meningitis and vasculitis in acquired immunodeficiency syndrome. A possible role for human immunodeficiency virus.
We describe the clinical and postmortem findings in a 57-year-old man with human immunodeficiency virus who presented with neurologic symptoms attributed to stroke. In addition to multiple foci of ischemic necrosis, pathologic examination of the brain showed chronic basal meningitis and vasculitis. No microorganisms were found. The association of meningitis and vasculitis in patients with acquired immunodeficiency syndrome is unusual and the possibility that these conditions may be due to primary human immunodeficiency virus infection is raised.
Scaravilli
F
F
Department of Neuropathology, National Hospital, Queen Square, London, England.
Daniel
S E
SE
Harcourt-Webster
N
N
Guiloff
R J
RJ
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000473:pathology; D001921:Brain / Q000473:pathology; D002908:Chronic Disease; D006679:HIV Seropositivity / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D008578:Meninges / Q000473:pathology; D008581:Meningitis / Q000150:complications* / Q000473:pathology; D008875:Middle Aged; D014657:Vasculitis / Q000150:complications* / Q000473:pathology