Aerosol transmission of Hantaan and related viruses to laboratory rats.
Hantaan, Seoul, and Puumala viruses were transmitted to 12-16-week-old female Wistar Rattus norvegicus by inhalation. The rodent infectious dose for each virus by intramuscular inoculation and by inhalation was determined, as was the infectious dose for Vero E-6 cells by direct plaque assay.
Nuzum
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Disease Assessment Division, U.S. Army Medical Research Institute of Infectious Disease, Fort Detrick, Frederick, Maryland 21701-5011.
Rossi
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CA
Stephenson
E H
EH
LeDuc
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JW
D000336:Aerosols; D000391:Air Microbiology; D000818:Animals; D005260:Female; D006476:Orthohantavirus / Q000502:physiology*; D006480:Hemorrhagic Fever with Renal Syndrome / Q000635:transmission*; D051381:Rats; D014709:Vero Cells
D000336:Aerosols