[Respiratory insufficiency in mucoviscidosis. Pathophysiologic aspects of conservative drug therapy].
The compensated chronic respiratory acidosis in a girl with cystic fibrosis changed into a mixed respiratory acidosis and metabolic alkalosis under the influence of therapeutic measures. As a consequence respiratory insufficiency worsened. Conservative management of the alkalosis alone both improved hypoxemia and hypercapnia without needing artificial ventilation.
Storm
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Kinderklinik des St. Vincenz Krankenhauses, Paderborn.
D000136:Acid-Base Equilibrium / Q000187:drug effects*; D002648:Child; D003131:Combined Modality Therapy; D003550:Cystic Fibrosis / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000008:administration & dosage; D011188:Potassium / Q000008:administration & dosage; D012131:Respiratory Insufficiency / Q000188:drug therapy*; D012965:Sodium Chloride / Q000008:administration & dosage; D013148:Spironolactone / Q000008:administration & dosage; D013806:Theophylline / Q000008:administration & dosage*
D006852:Hydrochlorothiazide; D013148:Spironolactone; D012965:Sodium Chloride; D013806:Theophylline; D011188:Potassium
Respiratorische Insuffizienz bei einer Mukoviszidose. Pathophysiologische Aspekte einer medikamentöskonservativen Therapie.