title: The p12f2/TaqI Y-specific polymorphism in three groups of Italians and in a sample of Senegalese.
abstract: The TaqI/p12f2 Y-specific RFLP was studied in 258 Italians (69 from North, 74 from Centre-South and 115 from Southern Sardinia) and in 65 Senegalese. The two allelic fragments of 10 and 8 kb characterizing this polymorphism were both found in the Italians but only the 10 kb band was found among the Senegalese. The observed frequency of the 8 kb allele was 32.4% in Central-Southern Italians, 17.4% in Northern Italians and 13.0% in Southern Sardinians. The last figure is significantly lower than that (34.3%) previously reported for a smaller sample of the same population.
authors.affiliation: Dipartimento di Biologia e Genetica per le Scienze Mediche, Università di Milano, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Brega
authors.forename: A
authors.initials: A
authors.lastname: Torroni
authors.forename: O
authors.initials: O
authors.lastname: Semino
authors.forename: L
authors.initials: L
authors.lastname: Maccioni
authors.forename: M
authors.initials: M
authors.lastname: Casanova
authors.forename: R
authors.initials: R
authors.lastname: Scozzari
authors.forename: M
authors.initials: M
authors.lastname: Fellous
authors.forename: A S
authors.initials: AS
authors.lastname: Santachiara-Benerecetti
mesh_terms: D000483:Alleles; D044383:Black People / Q000235:genetics; D002872:Chromosome Deletion; D004272:DNA, Mitochondrial / Q000032:analysis; D015252:Deoxyribonucleases, Type II Site-Specific; D005787:Gene Frequency; D006801:Humans; D007558:Italy; D008297:Male; D012150:Polymorphism, Restriction Fragment Length; D012675:Senegal; D044465:White People / Q000235:genetics; D014998:Y Chromosome / Q000648:ultrastructure*
chemical_list: D004272:DNA, Mitochondrial; D015252:Deoxyribonucleases, Type II Site-Specific; C027046:TCGA-specific type II deoxyribonucleases