Acute myocardial infarction due to coronary spasm associated with L-thyroxine therapy.
A 63-year-old man with hypothyroidism is described. He had been receiving L-thyroxine therapy following mitral valve surgery. About three weeks into the therapy regimen, he complained of severe retrosternal chest oppression. Electrocardiographic findings and laboratory data indicated a diagnosis of acute myocardial infarction due to the L-thyroxine therapy. Emergency selective coronary angiography was performed. Comparing his coronary angiograms with those obtained before surgery indicated a severely spastic left coronary artery. We believe this is the first report of myocardial infarction due to coronary spasm, demonstrated by angiography associated with L-thyroxine therapy.
Hiasa
Y
Y
Department of Cardiology, Komatsushima Red Cross Hospital, Tokushima, Japan.
Ishida
T
T
Aihara
T
T
Bando
M
M
Nakai
Y
Y
Kataoka
Y
Y
Mori
H
H
D000792:Angiography; D017023:Coronary Angiography; D003329:Coronary Vasospasm / Q000139:chemically induced*; D004562:Electrocardiography; D006801:Humans; D007037:Hypothyroidism / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000139:chemically induced*; D013974:Thyroxine / Q000009:adverse effects* / Q000627:therapeutic use
D013974:Thyroxine