[Effect of the thymus on the activity of immunoreactive peptides].
Influence of the thymic gland on the biology activity of peptide mediators--cytomedins, has been studied in the content of different organs. The peptide which was obtained from the liver, spleen and muscle of sham-operated animals enhanced immune response on the sheep red cells, lengthened indexes of thromboelastography, and activated fibrinolysis after its administration to the thymectomized rats. The peptides from organs of thymectomized animals lost this ability. These findings confirm the hypothesis on the regulating function of the thymic gland in the synthesis and activity of cytomedins in the tissues.
Kalashnikov
S G
SG
Kuznik
B I
BI
Tsybikov
N N
NN
D000818:Animals; D000917:Antibody Formation; D006487:Hemostasis; D007111:Immunity, Cellular; D007114:Immunization; D008099:Liver / Q000276:immunology; D009132:Muscles / Q000276:immunology; D010455:Peptides / Q000276:immunology*; D051381:Rats; D013154:Spleen / Q000276:immunology; D013934:Thymectomy; D013950:Thymus Gland / Q000276:immunology*
D010455:Peptides; C053892:cytomedins
Vliianie timusa na aktivnost' immunoreaktivnykh peptidov.