title: Systemic bone growth factors concentrations in calves during the perinatal period.
abstract: Plasma somatostatin (SRIF), growth hormone (GH), somatomedin C (IGF1), osteocalcin (BGP), 1,25-dihydroxyvitamin D (1,25-(OH)2D), calcium and inorganic phosphorus were measured in 10 chronically-catheterized fetal calves and in their dams during the two last months of gestation. Thus fetal life is associated with high levels of GH (1.53 +/- 0.14 nmol.l-1), BGP (64 +/- 4 nmol), Ca (2.90 +/- 0.06 nmol.l-1) compared to the results obtained in the pregnant cows. The first week of postnatal life was associated with a tremendous increase in plasma SRIF concentration (from 36 +/- 5 to 106 +/- 15 pmol.l-1; P less than 0.01). These results agree with an intense bone growth during the end of fetal life in the bovine species. However, IG 1 might not play a major role in the regulation of fetal skeletal growth during this period.
authors.affiliation: U.A.C.N.R.S. 1123, INRA Theix, Ceyrat, France.
authors.forename: V
authors.initials: V
authors.lastname: Coxam
authors.forename: M J
authors.initials: MJ
authors.lastname: Davicco
authors.forename: C
authors.initials: C
authors.lastname: Dardillat
authors.forename: F
authors.initials: F
authors.lastname: Opmeer
authors.forename: J P
authors.initials: JP
authors.lastname: Barlet
mesh_terms: D000818:Animals; D001846:Bone Development; D002118:Calcium / Q000097:blood; D002135:Calcium-Binding Proteins / Q000097:blood; D002417:Cattle / Q000097:blood*; D004100:Dihydroxycholecalciferols / Q000097:blood; D005314:Embryonic and Fetal Development; D005260:Female; D005312:Fetal Blood / Q000032:analysis*; D013006:Growth Hormone / Q000097:blood; D006133:Growth Substances / Q000097:blood*; D007334:Insulin-Like Growth Factor I / Q000097:blood; D015675:Osteocalcin; D010758:Phosphorus / Q000097:blood; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000097:blood*; D013004:Somatostatin / Q000097:blood
chemical_list: D002135:Calcium-Binding Proteins; D004100:Dihydroxycholecalciferols; D006133:Growth Substances; D015675:Osteocalcin; D010758:Phosphorus; D013004:Somatostatin; D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone; D002118:Calcium