[Effect of tuftsin on the leucyl aminopeptidase activity of the subcellular components in cerebral cortical formations].
The administration of a tetrapeptide tuftsin in a dose of 300 mkg/kg body weight for 15, 75 minutes leads to the change in specific activity of leucyl-arylamidase in subcellular component and their membrane which has been isolated from the rabbit sensomotor cortex and visual cortex. Reaction of a tetrapeptide depends on time. It is strongly pronounced in sensomotor cortex and has an advantage in synaptosomes and their membrane. Possibility of tuftsin in protein exchange of cellular and subcellular component is discussed.
Kamysheva
A S
AS
D000818:Animals; D002540:Cerebral Cortex / Q000187:drug effects* / Q000201:enzymology; D007931:Leucyl Aminopeptidase / Q000378:metabolism*; D011817:Rabbits; D013347:Subcellular Fractions / Q000187:drug effects / Q000201:enzymology; D013570:Synaptic Membranes / Q000187:drug effects / Q000201:enzymology; D013997:Time Factors; D014405:Tuftsin / Q000494:pharmacology*
D007931:Leucyl Aminopeptidase; D014405:Tuftsin
Vliianie taftsina na aktivnost' leĭtsilaminopeptidazy subkletochnykh komponentov korkovykh obrazovaniĭ mozga.