title: Immunohistochemical investigation of secretory component and immunoglobulin A in the genital tract of the female rat.
abstract: There was intense labelling of secretory component (sc) in the glandular and luminal epithelia of the uterine horns at pro-oestrus, oestrus and Day 1 of pregnancy, but at other stages labelling was weak or undetectable. There was also intense labelling of sc in the superficial layer of cells in the stratified epithelia of the cervix and vagina at pro-oestrus and Days 4-7 of pregnancy, but not at other stages. Plasma cells containing immunoglobulin A (IgA) were not observed in any region of the genital tract at any of the times studied. The presence of sc coupled with an absence of IgA-containing plasma cells suggest that IgA in genital tract secretions of the female rat may be derived mainly from serum.
authors.affiliation: Southern Illinois University, School of Medicine, Department of Anatomy, Carbondale 62901.
authors.forename: M B
authors.initials: MB
authors.lastname: Parr
authors.forename: E L
authors.initials: EL
authors.lastname: Parr
mesh_terms: D000818:Animals; D002584:Cervix Uteri / Q000276:immunology; D004971:Estrus / Q000276:immunology; D005260:Female; D005836:Genitalia, Female / Q000276:immunology*; D007070:Immunoglobulin A / Q000032:analysis*; D007071:Immunoglobulin A, Secretory / Q000032:analysis; D007128:Immunoglobulin Fragments / Q000032:analysis*; D010950:Plasma Cells / Q000276:immunology; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D012635:Secretory Component / Q000032:analysis*; D014599:Uterus / Q000276:immunology; D014621:Vagina / Q000276:immunology
chemical_list: D007070:Immunoglobulin A; D007071:Immunoglobulin A, Secretory; D007128:Immunoglobulin Fragments; D012635:Secretory Component