title: Ornithine-vasopressin gangrene and reconstruction of the upper lip. Case report.
abstract: A bilateral cleft lip and palate case received ornithine-vasopressin intra-operatively in preparation for a vasoconstricted field of the various lip segments prior to the repair of the cleft lip. A cyanotic tinge appeared immediately. This eventually led to total necrosis of the upper lip. Various relevant blood tests were done and a mild thrombocytosis was found. Surgical reconstruction of the upper lip was performed by means of a forked cross-lip flap--the main blood supply coming from the columella--as well as by means of an inferiorly pedicled cheek flap from the para-nasal area.
authors.affiliation: Department of Maxillo-Facial and Oral Surgery, University of Pretoria, South Africa.
authors.forename: K W
authors.initials: KW
authors.lastname: Bütow
authors.forename: T W
authors.initials: TW
authors.lastname: de Witt
authors.forename: F J
authors.initials: FJ
authors.lastname: Jacobs
mesh_terms: D002971:Cleft Lip / Q000601:surgery*; D002972:Cleft Palate / Q000601:surgery; D005734:Gangrene / Q000139:chemically induced* / Q000601:surgery; D006801:Humans; D007223:Infant; D008046:Lip / Q000601:surgery*; D008047:Lip Diseases / Q000139:chemically induced* / Q000601:surgery; D008297:Male; D009336:Necrosis; D009952:Ornithine / Q000009:adverse effects*; D013524:Surgical Flaps; D013922:Thrombocytosis / Q000503:physiopathology; D014667:Vasopressins / Q000009:adverse effects*
chemical_list: D014667:Vasopressins; D009952:Ornithine