[EEG changes and symptomatic parkinsonism after intracaudate administration of dopamine antibodies].
Intracaudate bilateral injection of the dopamine antibodies caused the formation of the generator of pathologically enhanced excitation in caudate nuclei. All the rats exhibited the oligokinesia, rigidity and head tremor were observed in most animals. These abnormalities could be observed during 24 hours. The possible role of dopamine antibodies in parkinsonism pathogenesis is discussed.
Kryzhanovskiĭ
G N
GN
Atadzhanov
M A
MA
Magaeva
S V
SV
Basharova
L A
LA
Vetrilé
L A
LA
D000818:Animals; D000906:Antibodies / Q000008:administration & dosage*; D002421:Caudate Nucleus / Q000503:physiopathology*; D004298:Dopamine / Q000276:immunology*; D004569:Electroencephalography; D008297:Male; D010302:Parkinson Disease, Secondary / Q000209:etiology / Q000503:physiopathology*; D011817:Rabbits; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D000906:Antibodies; D004298:Dopamine
Izmenenie EEG i iavleniia parkinsonizma pri intrakaudatnom vvedenii antitel k dofaminu.