Relative importance of estrogen and progesterone receptor assays as prognostic indicators in primary breast cancer: a short-term study.
This short-term study of the relative importance of estrogen and progesterone receptors shows that progesterone receptor correlates better than estrogen receptor with tumor recurrence regardless of lymph-node status. Life-table analysis has effectively identified only two groups of patients that may be classified by progesterone receptor status alone. Progesterone-receptor negativity correlated well with tumors of histological Grade III; estrogen-receptor positivity correlated with Grade I and II tumors. The earlier recurrence of Grade III breast tumors may explain why progesterone receptor is a better prognostic indicator than estrogen receptor in short-term studies.
Brocklehurst
D
D
Department of Clinical Chemistry, Doncaster Royal Infirmary, U.K.
Wilde
C E
CE
Finbow
J A
JA
Brett
R
R
Champion
A E
AE
Dewhurst
D G
DG
D001943:Breast Neoplasms / Q000032:analysis* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008593:Menopause; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis*; D011379:Prognosis; D011960:Receptors, Estrogen / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis*
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone