title: [Upper gastrointestinal bleeding from ulcer: reduction of mortality by early elective surgical therapy of patients at risk].
abstract: Amount, activity and localisation of bleeding, as well as patient-specific risk factors were used to define a group of patients at risk who were treated electively early by surgical intervention, within the first 24-36 hours after onset of the primary bleeding. 147 patients were included in the study between 1982 and 1988, a bleeding gastric ulcer being present in 67 (46%), a bleeding prepyloric ulcer in 14 (9%), and a bleeding duodenal ulcer in 66 (45%). 135 (92%) patients had a bleeding activity of I and II in Forrest's classification. 94 patients were in the at risk group and underwent early selective surgical treatment. During the period of study 13 patients (8.8%) died, with a drastic reduction in mortality rate during the 1982-1988 period from 20 to 0%. Stoppage of bleeding was the aim of operative intervention; treatment of the ulcerative condition was undertaken in only 43%. Reduction of the mortality rate to zero is ascribed to the early treatment concept.
authors.affiliation: Chirurgische Klinik und Poliklinik, Technischen Universität München.
authors.forename: J R
authors.initials: JR
authors.lastname: Siewert
authors.forename: R
authors.initials: R
authors.lastname: Bumm
authors.forename: A H
authors.initials: AH
authors.lastname: Hölscher
authors.forename: H J
authors.initials: HJ
authors.lastname: Dittler
mesh_terms: D000367:Age Factors; D004381:Duodenal Ulcer / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010438:Peptic Ulcer Hemorrhage / Q000401:mortality / Q000601:surgery*; D012307:Risk Factors; D012737:Sex Factors; D013276:Stomach Ulcer / Q000150:complications*; D013997:Time Factors
vernacular_title: Obere gastrointestinale Ulcusblutung--Letalitätssenkung durch früh-elektive chirurgische Therapie von Risikopatienten.