title: [X-ray diagnosis of renal osteopathy in dialysis patients with reference to clinical aspects].
abstract: Pathophysiological histological and radiological findings in renal osteodystrophy are described. Special emphasis is laid on secondary hyperparathyroidism. Preliminary results of the authors' investigations show a good correlation between radiological findings in the phalanges of the hand and the concentration of parathyroid hormone (PTH) in 14 patients. The concentration of the hormone in the blood was measured by a new "two-site" immunoradiometric assay, which is specific for the intact, biologically active hormone. Patients with high concentrations of PTH in the blood tended to have more severe radiological changes. In 4 patients for whom radiographs of the hands revealed no pathologic findings, normal PTH concentrations in the blood were measured by this method, whereas the conventional assay gave elevated hormone concentrations for the same patients. This is due to the lack of specificity of the conventional method for the intact, biologically active hormone. Nevertheless, further investigations are needed to confirm these findings.
authors.affiliation: Abteilung für Diagnostische Radiologie der II. Medizinischen Universitätsklinik Wien.
authors.forename: P
authors.initials: P
authors.lastname: Hübsch
authors.forename: S
authors.initials: S
authors.lastname: Trattnig
authors.forename: O
authors.initials: O
authors.lastname: Traindl
authors.forename: W
authors.initials: W
authors.lastname: Wolszczuk
authors.forename: P
authors.initials: P
authors.lastname: Barton
authors.forename: G
authors.initials: G
authors.lastname: Seidl
authors.forename: J
authors.initials: J
authors.lastname: Kovarik
mesh_terms: D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000097:blood / Q000000981:diagnostic imaging* / Q000209:etiology; D005260:Female; D006225:Hand / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000097:blood; D011859:Radiography; D006435:Renal Dialysis / Q000009:adverse effects*
chemical_list: D010281:Parathyroid Hormone
vernacular_title: Röntgendiagnostik der renalen Osteopathie bei Dialysepatienten unter Berücksichtigung klinischer Aspekte.