Genetics of the Lp lipoprotein in Japanese-Americans.
Segregation analysis of four Lp assays on 557 children in 227 families reveals a dominant major gene and a residual heritable component that may reflect one or more alleles of weaker effect. Close or moderate linkage to esterase-D (ESD) is excluded.
Morton
N E
NE
Berg
K
K
Dahlen
G
G
Ferrell
R E
RE
Rhoads
G G
GG
D000368:Aged; D000483:Alleles; D043182:Carboxylesterase; D002265:Carboxylic Ester Hydrolases / Q000235:genetics; D002648:Child; D003327:Coronary Disease / Q000097:blood / Q000235:genetics; D005260:Female; D005799:Genes, Dominant; D008040:Genetic Linkage; D006254:Hawaii; D006801:Humans; D007564:Japan / Q000208:ethnology; D017270:Lipoprotein(a); D008074:Lipoproteins / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D010641:Phenotype
D017270:Lipoprotein(a); D008074:Lipoproteins; D002265:Carboxylic Ester Hydrolases; D043182:Carboxylesterase; C020118:ESD protein, human