Central nervous system vasculitis in Behçet's syndrome: angiographic improvement after therapy with cytotoxic agents.
We describe a patient with Behçet's syndrome who had clinical and angiographic features of widespread cerebral angiitis of small- and medium-caliber vessels. We report the successful treatment of this condition with a combination of cytotoxic agents and steroids, and demonstrate angiographically the resolution of these abnormalities in neuro-Behçet's disease.
Zelenski
J D
JD
Department of Rheumatic and Immunologic Disease, Cleveland Clinic Foundation, OH 44195-5208.
Capraro
J A
JA
Holden
D
D
Calabrese
L H
LH
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001528:Behcet Syndrome / Q000150:complications*; D002533:Cerebral Angiography; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D002699:Chlorambucil / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008466:Mechlorethamine / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use
D000970:Antineoplastic Agents; D002699:Chlorambucil; D008466:Mechlorethamine; D011241:Prednisone