[Demonstration by spectroscopy NMR at 1,5 Tesla of changes in lipid/water ratio in pathology of the adrenal cortex].
By NMR proton spectrometry with a main field of approximately 1.5 Tesla the authors have studied on pieces obtained at surgery changes of the lipid/water ratio in the cortex of diseased adrenal glands. On the basis of 58 samples taken from 20 different glands they show that this ratio is comparable in hyperplasias and adenomas but quite significantly reduced in carcinomas. They are therefore of the opinion that this ratio might serve as a malignancy index in spectroscopic imaging of patients bearing tumors of the adrenal cortex.
D000236:Adenoma / Q000378:metabolism*; D000293:Adolescent; D000302:Adrenal Cortex / Q000473:pathology; D000306:Adrenal Cortex Neoplasms / Q000378:metabolism*; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000378:metabolism; D008055:Lipids / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D014867:Water / Q000032:analysis*
D008055:Lipids; D014867:Water
Mise en évidence par spectroscopie RMN à 1,5 Tesla des changements de la proportion lipides/eau en pathologie du cortex surrénalien.