Immunoreactive beta-endorphin increases after i.v. glucose in obese human subjects.
The plasma beta-endorphin of obese human subjects and non-obese controls was compared following the intravenous infusion of 25 grams of glucose. The plasma beta-endorphin of the obese subjects was significantly higher than controls one hour and four and one half hours after glucose infusion. The increased beta-endorphin of the obese subjects was associated with falling blood sugar.
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D002846:Chromatography, Affinity; D004723:Endorphins / Q000097:blood*; D005260:Female; D005947:Glucose / Q000494:pharmacology*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood*; D011863:Radioimmunoassay; D013997:Time Factors; D001615:beta-Endorphin
D001786:Blood Glucose; D004723:Endorphins; D001615:beta-Endorphin; D005947:Glucose