title: [Treatment of rosacea with isotretinoin. Results of a multicenter trial follow-up].
abstract: A follow up investigation was done on forty-seven patients of the German multicenter study with severe and long standing rosacea who had been treated with isotretinoin (0.5 mg/kg bw/day) over twelve or twenty weeks. During the post-treatment follow up which lasted an average of fifty-seven weeks, seven relapses were registered whereas forty patients remained in remission. After drug withdrawal, both the percentage of patients without inflammatory lesions (pustules, papules or nodules) as well as the mean values of inflammatory lesions remained almost constant over the whole observation period.
mesh_terms: D002986:Clinical Trials as Topic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015474:Isotretinoin; D008297:Male; D012008:Recurrence; D012393:Rosacea / Q000188:drug therapy*; D013997:Time Factors; D014212:Tretinoin / Q000627:therapeutic use*
chemical_list: D014212:Tretinoin; D015474:Isotretinoin
vernacular_title: Behandlung der Rosacea mit Isotretinoin. Ergebnisse einer posttherapeutischen multizentrischen Verlaufsbeobachtung.