Does nodular lymphocyte predominant Hodgkin's disease arise from progressively transformed germinal centres? A case report with an unusually prolonged history.
A case is reported of nodular lymphocyte predominant Hodgkin's disease arising 13 years after the removal of a lymph node from the same site which showed marked progressive transformation of germinal centres. The morphological evidence for a histogenetic relationship between the two conditions is presented and discussed.
D000328:Adult; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D003713:Dendritic Cells / Q000648:ultrastructure; D006649:Histocompatibility Antigens / Q000032:analysis; D006689:Hodgkin Disease / Q000032:analysis / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D017493:Leukocyte Common Antigens; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D013601:T-Lymphocytes / Q000276:immunology / Q000648:ultrastructure
D006649:Histocompatibility Antigens; D017493:Leukocyte Common Antigens