Differential induction of Escherichia coli autolysis by penicillin and the bacteriophage phi X174 gene E product.
The behavior of the temperature-sensitive, penicillin-tolerant Escherichia coli mutant VC44 to endogenously induced autolysis by the bacteriophage phi X174 gene E product (gpE) was investigated. Expression of the cloned phi X174 lysis gene showed that cultures of strain VC44 grown at the restricted temperature were fully sensitive to endogenously induced autolysis. The results revealed that the modes of E. coli lysis induction by gpE and by penicillin differ and that the trigger mechanisms for autolysis depend greatly on the specific inducer used.
D001329:Autolysis; D010584:Bacteriophage phi X 174 / Q000235:genetics*; D004926:Escherichia coli / Q000187:drug effects*; D005786:Gene Expression Regulation; D010406:Penicillins / Q000494:pharmacology*; D013696:Temperature; D014764:Viral Proteins / Q000494:pharmacology*
D010406:Penicillins; D014764:Viral Proteins