Concentration of metronidazole in rat serum and mandible.
The levels of metronidazole in rat serum and mandibular bones was measured 2, 5 and 8 h after oral administration of three doses of 200 mg/kg. Effective levels of the drug in serum and mandible were found at all time intervals as well as a higher concentration in mandible than in serum.
D000284:Administration, Oral; D000818:Animals; D008334:Mandible / Q000378:metabolism*; D008795:Metronidazole / Q000008:administration & dosage / Q000097:blood* / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D008795:Metronidazole