title: 123-Iodine heptadecanoic acid (HDA) cardiac metabolism of inactive sportsmen with nuclear cardiology, impacted into complex cardiological studies.
abstract: In 8 sportsmen and 8 healthy subjects of similar middle age the examination of the myocardial uptake of 123-I HDA and 201-T1 exhibited a correlation of r = 0.88 using our own quantitative circumferential evaluation program. The myocardial kinetics of the 123-I HDA was assessed by different methods: 1. according to Feinendegen et al. (1981), with complementary NaI-123 injection for the extra-myocardial background correction, 2. according to Dudczak (1984), with bi-exponential peeling, similar to the simplified method of the van Eenige group (1984, 1985). The utilisation-elimination kinetics resulted in comparable results with correlation coefficients of r = 0.80 and they were in accordance with the literature data; so this examination can be carried out without surplus NaI-123 injection, as well. The only significant difference was observed in some sportsmen who, after discontinuing the competitions, had a minimal delay of the HDA-kinetics in the septal region, where the echo-CG registered septal hypertrophy, as well. Otherwise the data of the HDA-kinetics, of the 201-T1 uptake and wash-out redistribution were in agreement with the results of the global and regional left ventricular ejection fractions, with the ECG at rest and during ergometric stress with the mechano-CG and with the cardio-volumetry, all exhibiting overlaps in the normal range between the sportsmen and healthy controls.
mesh_terms: D000328:Adult; D006332:Cardiomegaly / Q000000981:diagnostic imaging / Q000378:metabolism*; D005227:Fatty Acids / Q000378:metabolism*; D006321:Heart / Q000000981:diagnostic imaging; D006801:Humans; D007457:Iodine Radioisotopes; D007700:Kinetics; D009206:Myocardium / Q000378:metabolism*; D011877:Radionuclide Imaging; D013177:Sports; D013794:Thallium Radioisotopes
chemical_list: D005227:Fatty Acids; D007457:Iodine Radioisotopes; D013794:Thallium Radioisotopes; C013102:margaric acid