title: Hepatic and dermatologic manifestations of chronic hypervitaminosis A in adults. Report of two cases.
abstract: Chronic hypervitaminosis A in adults is a clinical syndrome that can develop over varying periods of time depending on the average daily intake of vitamin A. Two adult cases of chronic hypervitaminosis A are described and illustrate this diverse dosage-duration relationship. Hepatic cirrhosis developed as a manifestation of vitamin A toxicity in one of the patients; this appears to be the first reported case of chronic hypervitaminosis A in an adult induced by the long-term frequent ingestion of beef liver.
mesh_terms: D000328:Adult; D000505:Alopecia / Q000139:chemically induced*; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D006801:Humans; D006986:Hypervitaminosis A; D008103:Liver Cirrhosis / Q000139:chemically induced*; D008297:Male; D009974:Orthomolecular Therapy / Q000009:adverse effects