In vivo eight-day 'MLR' assay. A sensitive and reproducible method to detect simultaneously different organ-specific minor histocompatibility antigens in the mouse.
A previously described short 'in vivo MLR' technique was shown to be as sensitive as the long term skin graft technique for detecting minor histocompatibility antigens in 17 main organs of the mouse.
D000818:Animals; D005260:Female; D006087:Graft vs Host Reaction; D006649:Histocompatibility Antigens / Q000032:analysis*; D007959:Lymphocyte Culture Test, Mixed; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008912:Minor Histocompatibility Loci; D009928:Organ Specificity; D016038:Skin Transplantation
D006649:Histocompatibility Antigens