Gas chromatographic/mass spectrometric studies of the urinary metabolites of male rats given indan.
The identified urinary metabolites of male rats exposed to indan are: 1- and 2-indanone; 1-, 2- and 5-indanol; 2- and 3-hydroxyl-1-indanone; and cis- and trans-indan-1,2-diol. Indan causes kidney damage in male rats in a manner similar to the cyclic hydrocarbons cis- and trans-decalin and JP-10. Lesions produced by indan occur only in male rats and not in female or control rats.
D000284:Administration, Oral; D000818:Animals; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D007189:Indans / Q000008:administration & dosage / Q000652:urine*; D007192:Indenes / Q000652:urine*; D008297:Male; D051381:Rats
D007189:Indans; D007192:Indenes