[Phenotype of periparasitic hepatic infiltrating mononuclear cell in human alveolar echinococcosis].
Phenotypic analysis with monoclonal antibodies showed that OKT8+ T cells represent the main cell population of the periparasitic mononuclear cell infiltrate in the liver of 7 patients with alveolar echinococcosis. A significant decrease of the OKT8+ subpopulation had been previously demonstrated in the peripheral blood mononuclear cells of these patients. The results obtained in this study suggest an intrahepatic homing for these particular T cells. However, functional analysis of these cells is required in order to assess the physiopathological significance of these observations.
D000911:Antibodies, Monoclonal; D004445:Echinococcosis, Pulmonary / Q000473:pathology*; D006801:Humans; D008099:Liver / Q000473:pathology*; D009000:Monocytes / Q000166:cytology* / Q000276:immunology; D010641:Phenotype
D000911:Antibodies, Monoclonal
Etude phénotypique de l'infiltrat cellulaire mononucléé périparasitaire hépatique dans l'échinococcose alvéolaire humaine.