title: Prevalence of left-sided obstructive lesions in patients with atrioventricular canal without Down's syndrome.
abstract: Ninety consecutive patients with atrioventricular canal were studied to identify the association between left-sided obstructive lesions and Down's syndrome. Three groups were recognized: Group I, 76 patients with atrioventricular canal and no left-sided obstructions; Group II, nine patients with atrioventricular canal and left-sided inlet obstructions; Group III, five patients with atrioventricular canal and left-sided outlet obstructions. Of the 90 patients studied, 47 had Down's syndrome and only one of these had a left-sided obstructive lesion. Of 43 without Down's syndrome, 13 or 30% had left-sided obstructive lesions with predominating lesions at the inlet level caused by right ventricular dominance.
mesh_terms: D001017:Aortic Coarctation / Q000150:complications; D001024:Aortic Valve Stenosis / Q000150:complications; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000150:complications*; D004694:Endocardial Cushion Defects / Q000150:complications*; D005260:Female; D006343:Heart Septal Defects / Q000150:complications*; D006352:Heart Ventricles / Q000002:abnormalities*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male