Therapeutic immune regulation in experimental interstitial nephritis with suppressor T cells and their soluble factors.
The therapeutic application of immune regulation and suppressor T cells to the control and modulation of autoimmune disease is an area of growing experimental interest. Our group has been studying experimental interstitial nephritis, both to better understand the disease process itself and to test immunoregulatory strategies for their inhibitory and protective effects. This report gives a brief overview of this work.
D000818:Animals; D001323:Autoantibodies / Q000096:biosynthesis; D001327:Autoimmune Diseases / Q000276:immunology; D001485:Basement Membrane / Q000276:immunology; D006168:Guinea Pigs; D051379:Mice; D008954:Models, Biological; D009395:Nephritis, Interstitial / Q000276:immunology / Q000628:therapy*; D011817:Rabbits; D051381:Rats; D011914:Rats, Inbred BN; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*
D001323:Autoantibodies