Racial variations in the incidence of Trisomy 21.
A retrospective study compared the incidence of Trisomy 21 in immigrant Asians and indigenous Europeans, aged 40 years and over and delivered in the South Birmingham Health District over a 10 year period. A significantly lower (P less than 0.01) incidence of Trisomy 21 was observed in the Asian group than was expected, whereas the indigenous Europeans showed no significant difference from other European studies.
D000328:Adult; D004314:Down Syndrome / Q000453:epidemiology*; D005060:Europe; D005260:Female; D006801:Humans; D007194:India; D008423:Maternal Age; D008875:Middle Aged; D010298:Parity; D018566:Pregnancy, High-Risk; D044469:Racial Groups; D012189:Retrospective Studies