title: The receptor for immunoglobulin E as a membrane protein.
abstract: Mast cells and related cells have a surface glycoprotein that avidly binds monomeric immunoglobulin E (IgE). This protein is more complex than originally thought, its analysis having been complicated by its lability in mild detergents. The properties of this receptor, especially with respect to its interaction with lipids and detergents, is reviewed and the implications for the study of other membrane protein systems are discussed.
mesh_terms: D003902:Detergents; D004591:Electrophoresis, Polyacrylamide Gel; D007073:Immunoglobulin E; D008565:Membrane Proteins / Q000302:isolation & purification*; D017830:Octoxynol; D010743:Phospholipids; D011092:Polyethylene Glycols; D011961:Receptors, Fc / Q000302:isolation & purification*; D017455:Receptors, IgE; D011971:Receptors, Immunologic / Q000302:isolation & purification*
chemical_list: D003902:Detergents; D008565:Membrane Proteins; D010743:Phospholipids; D011961:Receptors, Fc; D017455:Receptors, IgE; D011971:Receptors, Immunologic; D007073:Immunoglobulin E; D011092:Polyethylene Glycols; D017830:Octoxynol; C010615:Nonidet P-40