Immunopathological changes after multiple spider bites.
Utilizing a panel of immune complex assays, antigen-antibody complex formation in a 29-year-old man shortly after a spider bite was documented. The clinical picture and laboratory parameters were consistent with a serum sickness reaction. Immune hyperactivity was evidenced by a detectable autoimmune serological response. This constellation of findings may be a common attendant to arthropod envenomation.
D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D000936:Antigen-Antibody Complex / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D006801:Humans; D007105:Immune Complex Diseases / Q000209:etiology*; D008297:Male; D012698:Serologic Tests; D012713:Serum Sickness / Q000209:etiology; D001098:Spider Bites / Q000276:immunology*
D000974:Antibodies, Antinuclear; D000936:Antigen-Antibody Complex; D003181:Complement C4