title: Intraarterial cisplatin infusion: nursing implications.
abstract: Patients diagnosed with malignant intracranial tumors have limited chemotherapeutic options. Recent studies have shown that intraarterial infusions of antineoplastic agents to regionally confined malignancies may be of great benefit. Clinical trials of intraarterial infusions of the drug cisplatin are investigating its efficacy in treating intracerebral gliomas. This paper presents the rationale for such treatment and emphasizes nursing responsibilities relative to the treatment protocols.
mesh_terms: D001812:Blood-Brain Barrier; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000503:physiopathology; D002453:Cell Cycle; D002945:Cisplatin / Q000008:administration & dosage* / Q000378:metabolism; D005910:Glioma / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000451:nursing*; D009730:Nursing Assessment; D009733:Nursing Diagnosis; D010351:Patient Discharge
chemical_list: D002945:Cisplatin