[Circulating immune complexes in the pathogenesis of recurrent erysipelas].
The dynamics of circulating immune complexes (CIC) in comparison with the level of SH-groups of serum deproteinate and other characteristics of cell-mediated and humoral immunity (the reaction of the inhibition of antibodies, the levels of T-cells and their main subpopulations) was studied in 103 erysipelas patients and in 46 persons having had the disease at the acute period of this infection and at the periods between relapses. The elevated levels of CIC and SH-groups of serum deproteinate were found to be directly correlated with the inhibition index. The study showed that, as a rule, in patients with the elevated level of CIC the frequently relapsing form of erysipelas, accompanied by the formation of relative hypersuppressor-type secondary immunodeficiency and by a decrease in the functional activity of dermal macrophages, was observed.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000936:Antigen-Antibody Complex / Q000032:analysis / Q000276:immunology*; D003289:Convalescence; D004886:Erysipelas / Q000209:etiology* / Q000276:immunology; D006801:Humans; D007113:Immunity, Innate; D007958:Leukocyte Count; D008264:Macrophages / Q000276:immunology; D008875:Middle Aged; D011379:Prognosis; D012008:Recurrence; D012867:Skin / Q000276:immunology; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
D000936:Antigen-Antibody Complex
Tsirkuliruiushchie immunnye kompleksy v patogeneze retsidiviruiushcheĭ rozhi.