title: [Vitamin A: an indirect factor in the prevention of cancer].
abstract: Although vitamin A intervenes essentially in the mechanism of sight, its possible role in the prevention and treatment of cancer is widely discussed. Epidemiological studies have demonstrated a correlation between vitamin A deficiency and an increase in the frequency of cancers in man. Several hypotheses have been put forward concerning the mechanism of interaction between vitamin A and cancer on the basis of experimental models showing that vitamin A exerts a protective action against spontaneous or induced neoplasias in animals. The toxicological aspects of vitamin A administration and the relevance of these experimental results to human oncology are discussed.
mesh_terms: D002454:Cell Differentiation; D006801:Humans; D009369:Neoplasms / Q000097:blood / Q000517:prevention & control*; D014801:Vitamin A / Q000008:administration & dosage* / Q000097:blood / Q000276:immunology / Q000494:pharmacology
chemical_list: D014801:Vitamin A
vernacular_title: La vitamine A: un facteur de prévention indirect du cancer.