title: Mandibular resorption from silicone chin implants in children.
abstract: Silicone implants were placed in the nasal, cheek, and chin areas in children with Down's syndrome to improve facial appearance. Clinical and radiologic follow-up evaluation revealed significant crater-like bone resorption in the mandibular symphysis in 75% of the cases. All of these implants were removed, and the bone showed regrowth to the presurgical state. No sign of bone damage was present in the malar or nasal areas.
mesh_terms: D000293:Adolescent; D000328:Adult; D001862:Bone Resorption / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D002680:Chin / Q000502:physiology / Q000601:surgery; D004129:Dimethylpolysiloxanes; D004314:Down Syndrome / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000209:etiology*; D008341:Mandibular Prosthesis / Q000009:adverse effects*; D009295:Nasal Bone / Q000601:surgery; D012828:Silicones; D013518:Surgery, Plastic; D014945:Wound Healing; D015050:Zygoma / Q000601:surgery
chemical_list: D004129:Dimethylpolysiloxanes; D012828:Silicones