On the stimulating capacity of human leukemic REH cells in a mixed lymphocyte culture.
In contrast to earlier studies, the presence of a stimulating capacity of cultured leukemic REH cells in a mixed lymphocyte culture is demonstrated. Supernatants of REH cells in a 1:10 final dilution were found to inhibit lymphocyte proliferation by about 30%. Mycoplasma contamination may introduce serious artefacts in all experimental systems which detect lymphocyte proliferation by means of incorporation of 3H-thymidine.
D002460:Cell Line; D002478:Cells, Cultured; D006801:Humans; D007945:Leukemia, Lymphoid / Q000276:immunology*; D008213:Lymphocyte Activation; D007959:Lymphocyte Culture Test, Mixed; D008214:Lymphocytes / Q000166:cytology / Q000276:immunology*