title: Coexistence of atrial natriuretic factor (ANF) and oxytocin in neurons of the rat hypothalamus.
abstract: Sections of rat hypothalamus were examined immunocytochemically for coexistence of atrial natriuretic factor (cardiodilatin) and oxytocin. These biosynthetically unrelated neuropeptides were demonstrated using the peroxidase-antiperoxidase method followed by immunofluorescence. Neurons immunoreactive for atrial natriuretic factor were found in the supraoptic, periventricular and paraventricular nuclei. A sub-population of these neurons contained oxytocin-like immunoreactivity. They constitute only a small portion of the total number of oxytocinergic neurons.
mesh_terms: D000818:Animals; D000936:Antigen-Antibody Complex / Q000032:analysis; D009320:Atrial Natriuretic Factor / Q000032:analysis*; D005260:Female; D007031:Hypothalamus / Q000166:cytology*; D007124:Immunoenzyme Techniques; D009474:Neurons / Q000166:cytology*; D010121:Oxytocin / Q000032:analysis*; D051381:Rats
chemical_list: D000936:Antigen-Antibody Complex; C472610:atrial natriuretic peptide, rat; D010121:Oxytocin; D009320:Atrial Natriuretic Factor