title: Chloracne and chloracnegens.
abstract: Chloracne, an acneform eruption resulting from poisoning by halogenated aromatic compounds, has been a considerable problem over the last 40 years. The condition is always a symptom of systemic poisoning and should be familiar to all practitioners, particularly dermatologists. It is difficult to treat and can last for long periods without known additional exposure to chloracnegens. Some chloracnegens are capable of causing a variety of systemic signs and symptoms and may be oncogenic. Although there are probably fewer than 4,000 persons with chloracne worldwide, those found with the disorder should be evaluated medically on a regular basis and followed, if possible, throughout their lives.
mesh_terms: D015085:2,4,5-Trichlorophenoxyacetic Acid / Q000009:adverse effects; D015084:2,4-Dichlorophenoxyacetic Acid / Q000009:adverse effects; D000152:Acne Vulgaris / Q000139:chemically induced* / Q000473:pathology / Q000628:therapy; D000075182:Agent Orange; D000814:Aniline Compounds; D000818:Animals; D001391:Azo Compounds / Q000009:adverse effects; D001572:Benzofurans / Q000009:adverse effects; D001713:Biphenyl Compounds / Q000009:adverse effects; D055598:Chemical Phenomena; D002621:Chemistry; D000072338:Dibenzofurans, Polychlorinated; D004147:Dioxins / Q000009:adverse effects; D004340:Drug Contamination; D006219:Halogens / Q000009:adverse effects; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000009:adverse effects; D009281:Naphthalenes / Q000009:adverse effects; D009369:Neoplasms / Q000139:chemically induced; D000072317:Polychlorinated Dibenzodioxins / Q000009:adverse effects
chemical_list: D000814:Aniline Compounds; D001391:Azo Compounds; D001572:Benzofurans; D001713:Biphenyl Compounds; D000072338:Dibenzofurans, Polychlorinated; D004147:Dioxins; D006219:Halogens; D006843:Hydrocarbons, Chlorinated; D009281:Naphthalenes; D000072317:Polychlorinated Dibenzodioxins; C014464:3,4-dichloroaniline; D015084:2,4-Dichlorophenoxyacetic Acid; D000075182:Agent Orange; C023614:dibenzofuran; D015085:2,4,5-Trichlorophenoxyacetic Acid; C009850:azobenzene; C046115:fenazox