title: Major depression in cardiology chest pain patients without coronary artery disease and with panic disorder.
abstract: 104 patients in a cardiology clinic with atypical or non-anginal chest pain were studied through a structured clinical interview. 43 without coronary artery disease fit diagnostic criteria for panic disorder. 19 (44%) of this group reported a lifetime prevalence of major depression, nine (21%) current and ten (23%) past only. Nine reported that their major depressive episodes had preceded the onset of their panic disorder. On many self-report questionnaire scales the group with a lifetime history of major depression (n = 19) differed significantly from the group with no lifetime history of major depression (n = 24). These differences, however, could be attributed primarily to the group with current major depression. There appears to be a subgroup of panic disorder patients who have current major depression who are more symptomatic than those with panic disorder and past major depression and panic disorder alone. These findings also suggest that the association between panic disorder and depression may remain high outside of psychiatric settings.
mesh_terms: D000328:Adult; D001008:Anxiety Disorders / Q000150:complications*; D002637:Chest Pain / Q000150:complications*; D003866:Depressive Disorder / Q000150:complications*; D005239:Fear; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010200:Panic; D013997:Time Factors