title: Syndrome of erythroderma, failure to thrive, and diarrhea in infancy: a manifestation of immunodeficiency.
abstract: Five infants with a triad of symptoms comprising generalized erythroderma, failure to thrive, and diarrhea are presented. All of these children demonstrated significant immunologic abnormalities. This is a recognizable clinical syndrome that reflects immunodeficiency; however, the responsible immunodeficiencies do not appear to be the same in every case. Early investigation and appropriate therapy may considerably reduce morbidity, and mortality in children with this syndrome.
mesh_terms: D002675:Child, Preschool; D003873:Dermatitis, Exfoliative / Q000151:congenital / Q000276:immunology / Q000628:therapy; D003968:Diarrhea, Infantile / Q000276:immunology / Q000628:therapy; D005183:Failure to Thrive / Q000276:immunology / Q000628:therapy; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007153:Immunologic Deficiency Syndromes / Q000276:immunology; D007223:Infant; D008297:Male
chemical_list: D007136:Immunoglobulins