Simultaneous determination of captopril and S-benzoyl captopril in human blood by capillary gas chromatography-mass selective detection.
Using a new table-top electron-impact mass selective detector, interfaced with a narrow bore, fused silica capillary gas chromatograph, a method has been developed for the simultaneous determination of captopril and S-benzoyl captopril. With a capillary column the two components could be chromatographically resolved, thus permitting the use of electron-impact ionization for quantitative measurements.
D002216:Captopril / Q000031:analogs & derivatives* / Q000097:blood*; D004355:Drug Stability; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007202:Indicators and Reagents; D008745:Methylation
D007202:Indicators and Reagents; C046814:S-benzoyl captopril; D002216:Captopril