Speech timing in Parkinson's and Huntington's disease.
The purpose was to determine the effects of two different basal ganglia diseases on speech planning, initiation, and production. Patients with Parkinson's Disease (PD) and Huntington's Disease (HD) were compared with normal subjects on speech timing tasks. Speech reaction time was unimpaired, while changes in duration at different speech rates were affected differently in the two patient groups. In HD, changes in the duration of syllables, of pauses between phrases, and of sentences were all reduced, while in PD only the control of sentence duration was impaired. The HD patients had reduced syllable repetition rates, but both patient groups maintained their repetition rates over 5 sec. The ratios of word to phrase time, and of phrase to sentence time, remained constant across regular and fast speaking rates and did not differ from normal in either patient group. The results suggest that PD and HD patients are not impaired in speech planning or initiation, but have poor control over the duration of speech events.
D001479:Basal Ganglia / Q000503:physiopathology; D004401:Dysarthria / Q000503:physiopathology; D006801:Humans; D006816:Huntington Disease / Q000503:physiopathology*; D010300:Parkinson Disease / Q000503:physiopathology*; D010700:Phonetics; D011930:Reaction Time / Q000502:physiology; D013068:Speech Production Measurement