Production of polyclonal antibodies against the cellular IFN-gamma receptor.
In this work we consider the possibility to produce a polyclonal antibody against murine interferon gamma receptors by immunizing rabbits with the complex receptor-IFN-gamma immunoprecipitated by a monoclonal antibody (AN-18) recognising the ligand bound to the receptor. Using the Western Blotting technique it has been found a polyclonal serum directed against a protein (90 kDa) that could represent the murine IFN-gamma membrane receptor.
D000818:Animals; D000906:Antibodies / Q000276:immunology*; D000911:Antibodies, Monoclonal / Q000276:immunology; D008970:Molecular Weight; D011817:Rabbits; D011971:Receptors, Immunologic / Q000187:drug effects / Q000276:immunology*; D017471:Receptors, Interferon; D013045:Species Specificity
D000906:Antibodies; D000911:Antibodies, Monoclonal; D011971:Receptors, Immunologic; D017471:Receptors, Interferon