title: Mutilating palmo-plantar keratoderma.
abstract: This is the sixth case of mutilating palmo-plantar keratoderma, which is characterized by extensive ichthyosis and thickening of skin with accentuated skin markings histologically resembling acanthosis nigricans.
mesh_terms: D000328:Adult; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000235:genetics / Q000473:pathology*; D008297:Male