Papillon-Lefevre syndrome. A report of six cases in one family.
Papillon-Lefevre syndrome in six Saudi children in the same family is described. The parents were unaffected, and parental consanguinity was present. Palmoplantar keratosis started at the age of 1 1/2 years. The loss of deciduous teeth was a consequence of juvenile periodontitis. All essential features of the syndrome were present in this series.
D000293:Adolescent; D010520:Aggressive Periodontitis / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000235:genetics*; D008297:Male; D010214:Papillon-Lefevre Disease / Q000150:complications / Q000235:genetics*; D010375:Pedigree; D012529:Saudi Arabia