title: Extended study of aneurysm formation in umbilical vein grafts.
abstract: The rate of aneurysm formation in umbilical vein grafts has been reported to lie between 1% and 8%. However, in these reported series the number of grafts with aneurysms was related to the number of grafts inserted. When the denominator is changed to patent grafts at a given time period, the incidence changes drastically. In this study, duplex scanning was used to detect aneurysms in patent grafts. Four types of aneurysms--localized fusiform, localized eccentric, diffuse, and anastomotic--were recognized. Excluding anastomotic aneurysms, 33% of the grafts patent at 3 years were aneurysmal; in those patent at 4 years, 45% were aneurysmal; and in those patent at 5 or more years, 65% were aneurysmal. On grounds of theoretical considerations, it is believed that duplex scanning is more reliable than either clinical examination or arteriographic study for detecting these aneurysms. There is now evidence that the supporting Dacron mesh is too weak and must be strengthened. Despite aneurysm formation, the patency rate in our series has remained second only to saphenous vein grafts, as previously reported.
mesh_terms: D000783:Aneurysm / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology*; D005500:Follow-Up Studies; D006801:Humans; D011093:Polyethylene Terephthalates; D011183:Postoperative Complications / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology*; D013526:Surgical Mesh; D013997:Time Factors; D014463:Ultrasonography; D014471:Umbilical Veins / Q000637:transplantation*; D014654:Vascular Patency
chemical_list: D011093:Polyethylene Terephthalates