Bisucaberin, a new siderophore, sensitizing tumor cells to macrophage-mediated cytolysis. II. Physico-chemical properties and structure determination.
The structure of bisucaberin, a new siderophore, was determined to be 1,12-dihydroxy-1,6,12,17-tetraazacyclodocosane-2,5,13,16-tetron e by spectroscopic analysis and X-ray crystallographic analysis. The molecule of bisucaberin consists of a cyclic dimer of 1-hydroxy-1,6-diazaundecane-2,5-dione moiety and is closely related to nocardamine, the trimer of the same moiety.
D000970:Antineoplastic Agents; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006860:Hydrogen Bonding; D007502:Iron Chelating Agents; D009682:Magnetic Resonance Spectroscopy; D010456:Peptides, Cyclic / Q000302:isolation & purification* / Q000494:pharmacology; D017262:Siderophores; D013055:Spectrophotometry, Infrared
D000970:Antineoplastic Agents; D007502:Iron Chelating Agents; D010456:Peptides, Cyclic; D017262:Siderophores; C054842:bisucaberin