Effect of thymectomy on myasthenia gravis and autoimmune thrombocytopenic purpura in a 13-year-old girl.
We report the association of myasthenia gravis (MG) and autoimmune thrombocytopenic purpura (AITP) in a 13-year-old girl. The co-existence of these autoimmune diseases is rare in adults and, to our knowledge, never described in children. In our patient thymectomy had a therapeutic effect on both MG and AITP, suggesting a altered T-cell function as a pathogenic factor of major importance in both affections.
D000293:Adolescent; D001327:Autoimmune Diseases / Q000150:complications / Q000601:surgery; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D009157:Myasthenia Gravis / Q000150:complications / Q000276:immunology / Q000601:surgery*; D010976:Platelet Count; D011696:Purpura, Thrombocytopenic / Q000150:complications / Q000276:immunology / Q000601:surgery*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology; D013934:Thymectomy
D007074:Immunoglobulin G