The role of thyroid and adrenal cortical hormones in the modulation of the gonadal function in birds.
The role of the thyroid gland in modulating the gonad function depends on the functional state of the gonads. In sexually inactive (short-day's) male Japanese quails, thyroidectomy and thyroxine treatment prove ineffective. Thyroxine administered simultaneously with photo-gonadostimulation inhibits the maturation of the gonads: the testes decrease in weight, the metabolic clearance rate of testosterone accelerates, resulting in a decrease in the plasma level, and androsterone production increases. Photo-gonadostimulation of thyroidectomized quails shows down the growth of the testicles and decreases the plasma testosterone level. The latter change can be related to the inhibition of the secretion rate. Both thyroidectomy and thyroxine administration performed in mature male quail, cock, pigeon or Peking duck lower the testosterone plasma level. The loss of the testicular weight is more expressed in hyperthyroid than in normal quails, referring to the role of the increased thyroxine level in the seasonal (summer) gonadal involution. Thyroidectomy performed on sexually inactive (short-day's) female Japanese quails does not affect the ovarian structure, but 17 beta-oestradiol and testosterone plasma levels show a slight increase. Thyroxine administration is followed by a moderate increase in the size of the white follicles, and an increase of both the progesterone and the oestrogen concentrations. Photo-gonadostimulation of thyroidectomized quails causes an inhibition of the mechanism of ovulation without inhibiting the development of the yellow follicles. A similar phenomenon has been observed in mature quails and domestic fowls after thyroidectomy. In both cases, an unbalanced secretion of the sexual steroids occurs: the 17 beta-oestradiol plasma level declines, while the progesterone level increases. Simultaneous application of thyroxine and photo-gonadostimulation on female quails inhibits gonadal maturation: the growing of the yellow follicles slows down. In thyroxine-treated birds, the plasma level of all of the sexual steroids shows a considerable decrease, which can be attributed to a reduced secretion rate and increased metabolic clearance. In hatching turkeys, we failed to observe the increase of the T3 level described for other species, however, the T4 plasma concentration was increasing at the early period of hatching. The role of the thyroid hormones in the development of hatching has not been cleared up so far. Corticosterone administration shows a slight stimulating effect on the gonadal function of sexually inactive male and female Japanese quails.(ABSTRACT TRUNCATED AT 400 WORDS)
D000311:Adrenal Glands / Q000502:physiology; D000818:Animals; D001717:Birds / Q000502:physiology*; D010856:Columbidae / Q000502:physiology; D003345:Corticosterone / Q000494:pharmacology*; D003370:Coturnix / Q000502:physiology; D004372:Ducks / Q000502:physiology; D004958:Estradiol / Q000378:metabolism; D004970:Estrone / Q000378:metabolism; D005260:Female; D008297:Male; D008657:Metabolic Clearance Rate; D009929:Organ Size; D010053:Ovary / Q000187:drug effects / Q000502:physiology*; D011200:Poultry / Q000502:physiology; D011374:Progesterone / Q000378:metabolism; D012636:Secretory Rate; D013737:Testis / Q000187:drug effects / Q000502:physiology*; D013739:Testosterone / Q000378:metabolism; D013961:Thyroid Gland / Q000502:physiology*; D013965:Thyroidectomy; D013974:Thyroxine / Q000494:pharmacology*; D014422:Turkeys / Q000502:physiology
D004970:Estrone; D013739:Testosterone; D011374:Progesterone; D004958:Estradiol; D013974:Thyroxine; D003345:Corticosterone