title: [Development of a model to study the anti-edema properties of Ginkgo biloba extract].
abstract: The vasogenic edema observed after irradiation of the brain constitutes a new and interesting model to study the anti-oedema properties of drugs. We have just completed a first pharmaco-clinical study of Ginkgo biloba extract with the dual purpose of assessing the feasibility of a therapeutic protocol and of deciding on simple and non-invasive criteria that would quantity cerebral oedema. The results of this pilot study have encouraged us to pursue our investigations under strict methodological conditions, in view of their therapeutic but also epidemiological interest.
mesh_terms: D001929:Brain Edema / Q000188:drug therapy* / Q000209:etiology; D001932:Brain Neoplasms / Q000150:complications / Q000628:therapy; D003131:Combined Modality Therapy; D004341:Drug Evaluation / Q000379:methods; D005260:Female; D005910:Glioma / Q000150:complications / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000627:therapeutic use; D010946:Plants, Medicinal; D011878:Radiotherapy / Q000009:adverse effects; D014197:Trees
chemical_list: D010936:Plant Extracts
vernacular_title: Mise au point d'un modèle d'étude des propriétés anti-oedémateuses de l'extrait de Ginkgo biloba.