Experimental gingivitis in a Down's syndrome child and sibling.
Biopsies were taken from a child with Down's syndrome and her sibling under experimental gingivitis conditions and analyzed with monoclonal antibodies. At first, plaque caused a shift from a predominance of T cells to a predominance of B cells. Later, a gradual increase of T cells and a looser arrangement of B cells were observed.
D001402:B-Lymphocytes / Q000276:immunology*; D002648:Child; D003773:Dental Plaque / Q000276:immunology*; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D005891:Gingivitis / Q000150:complications / Q000276:immunology*; D006681:HLA-D Antigens / Q000276:immunology; D006801:Humans; D008264:Macrophages / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
D006681:HLA-D Antigens