Nonspecific chronic inflammatory bowel disease and AIDS.
A male patient with a 14-year history of UC (ulcerative colitis) had a helper-suppressor ratio (H/S) of 0.25 during a suspected exacerbation of chronic colitis. Prednisone and sulfasalazine were administered. Despite a transient clinical response he developed AIDS (acquired immune deficiency syndrome) and KS (Kaposi's sarcoma) within 3 months of initiating therapy.
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000209:etiology; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D003093:Colitis, Ulcerative / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D003424:Crohn Disease / Q000150:complications / Q000276:immunology; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D008297:Male; D012514:Sarcoma, Kaposi / Q000150:complications / Q000209:etiology; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents