[Characteristics of the function of the pentosephosphate pathway in the mucous membrane of the gastrointestinal tract of rats with vitamin PP deficiency and stress-induced ulcer].
Characteristics of the pentosephosphate pathway function were studied in the gastrointestinal mucosa of niacin-deficient rats with stress-induced ulcers. A decreased activity of the pentosephosphate pathway oxidative enzymes was recorded in rats with PP-hypovitaminosis. The levels of oxidated and reduced forms of NADP were lowered while transketolase activity and aldopentose amount rose. Activity of the nonoxidative component of the pentosephosphate pathway increased while that of oxidative reactions decreased in rats with stress-induced ulcers. Stress produced in the presence of niacin-deficiency did not significantly influence the pentosephosphate pathway in the gastroduodenal mucosa.
D000818:Animals; D005753:Gastric Mucosa / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000378:metabolism*; D007421:Intestine, Small / Q000378:metabolism; D008297:Male; D009536:Niacinamide / Q000172:deficiency*; D010084:Oxidation-Reduction; D010427:Pentose Phosphate Pathway; D051381:Rats; D012149:Restraint, Physical; D013276:Stomach Ulcer / Q000378:metabolism*; D013315:Stress, Psychological / Q000150:complications
D009536:Niacinamide
Osobennosti funktsionirovaniia pentozofosfatnogo puti v slizistoĭ obolochke zheludochno-kishechnogo trakta PP-gipovitaminoznykl krys s iazvoĭ, vyzvannoĭ stressom.