Iohexol and ioxaglate in peripheral angiography.
A double-blind, cross-over trial of the non-ionic, low-osmolar contrast medium iohexol (Omnipaque) and the ionic, low-osmolar medium ioxaglate (Hexabrix) at concentrations of 300 mg I/ml was carried out in 107 consecutive patients with arterial insufficiency of the lower limbs. The purpose of the study was to observe possible 'carry-over' effects from any of the contrast media, and to evaluate patient discomfort such as pain, adverse reactions, or effect on peripheral blood pressure. No carry-over effect was seen. Ioxaglate caused less injection pain and heat sensations than iohexol, and showed less effect on the systemic blood pressure.
D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007472:Iohexol / Q000009:adverse effects*; D007485:Ioxaglic Acid / Q000008:administration & dosage*; D007866:Leg / Q000098:blood supply; D008297:Male; D008875:Middle Aged
D007472:Iohexol; D007485:Ioxaglic Acid