[Hepatitis due to pirprofen; 3 cases, 1 fatality].
We report three cases of jaundice in women taking 800 mg pirprofen.day-1 during 6 weeks to 4 months and a half. Two of them presented cutaneous side effects: one case was rapidly better with corticosteroids. Fatal case possibility incite to transaminase surveillance.
D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D004334:Drug Administration Schedule; D003875:Drug Eruptions / Q000209:etiology; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D008875:Middle Aged; D010666:Phenylpropionates / Q000008:administration & dosage / Q000009:adverse effects*; D011239:Prednisolone / Q000627:therapeutic use
D000894:Anti-Inflammatory Agents, Non-Steroidal; D010666:Phenylpropionates; D011239:Prednisolone; C008924:pirprofen
Hépatite au pirprofène; 3 cas dont 1 mortel.