A model of two conformational forms of heparins/heparans suggested by infrared spectroscopy.
Results of infrared spectroscopy of complexes between cations and heparins, heparans and chemically-modified polymers suggest the existence of two conformational forms of heparins/heparans, differing in their modes of interaction with cations. Functions of heparans at normal and cancer cell surfaces are discussed in the light of this model.
D002236:Carbohydrate Conformation; D006025:Glycosaminoglycans; D006493:Heparin; D006497:Heparan Sulfate; D008956:Models, Chemical; D013055:Spectrophotometry, Infrared; D013451:Sulfonic Acids
D006025:Glycosaminoglycans; D006493:Heparin; D006497:Heparan Sulfate; D013451:Sulfonic Acids