title: [The effect of topical treatment in the treatment of disease in ankle sprains].
abstract: The efficacy of Mobilat ointment (100 g contain: Extract. suprarenale 1.0 g, Mucopolysaccharide-polysulfate 0.2 g, salicylic acid 2.0 g) in the treatment of acute lateral distortions of the ankle was tested in a randomised, placebo-controlled, double blind study. The criteria used for the assessment of the progress of healing were the pressure distribution during walking, the swelling of the injured region and the evaluation of pain using a visual analogue scale. During the period of treatment and observation lasting 2 weeks, all the assessment criteria showed a more rapid regression in the symptoms and signs of the disorder on treatment with the active product. The differences were statistically significant for all the criteria assessed.
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D016512:Ankle Injuries; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004338:Drug Combinations / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006025:Glycosaminoglycans / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009824:Ointments; D011897:Random Allocation; D012459:Salicylates / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D020156:Salicylic Acid; D013180:Sprains and Strains / Q000188:drug therapy* / Q000503:physiopathology; D014020:Tissue Extracts / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D000893:Anti-Inflammatory Agents; D004338:Drug Combinations; D006025:Glycosaminoglycans; D009824:Ointments; D012459:Salicylates; D014020:Tissue Extracts; C039329:mobilat; D020156:Salicylic Acid
vernacular_title: Einfluss einer topischen Behandlung auf den Krankheitsverlauf bei Sprunggelenks-Distorsionen.