title: Annexins--new family of Ca2+-regulated-phospholipid binding protein.
abstract: Calcium and phospholipid binding proteins have been identified and localized by immunocytochemistry in a wide range of cells and tissues. Two of these proteins (calpactins) also bind F-actin and are substrates for tyrosine kinases. The similar membrane-binding properties of these molecules arise from conserved amino acid sequences and a model is proposed for the tertiary structure of a common calcium and phospholipid binding domain.
mesh_terms: D000818:Animals; D017302:Annexins; D002135:Calcium-Binding Proteins / Q000032:analysis* / Q000378:metabolism; D002352:Carrier Proteins / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D010743:Phospholipids / Q000378:metabolism; D011505:Protein-Tyrosine Kinases / Q000378:metabolism
chemical_list: D017302:Annexins; D002135:Calcium-Binding Proteins; D002352:Carrier Proteins; D010743:Phospholipids; D011505:Protein-Tyrosine Kinases