[Post-neurosurgical purulent meningitis. 31 cases].
Thirty-one cases of post neurosurgical bacterial meningitis from one center were reviewed to determine their promoting factors and responsible organisms. Most cases occurred after a protracted operation (6 hours on average). 26% cases were related to a primary cutaneous infection. 58% organisms were Gram negative bacilli. The course of meningitis was often complicated or prolonged due to a scalp decubitus ulcer or cerebrospinal fluid leakage. Vancomycin is often requested during staphylococcal meningitis. Third generation cephalosporins have low MIC against many Gram negative bacilli and should be used. Pefloxacin, a new quinolone, may be valuable. Treatment of scalp wound infection is often requested.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002493:Central Nervous System Diseases / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008581:Meningitis / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000209:etiology*; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology*; D012189:Retrospective Studies
D000900:Anti-Bacterial Agents
Méningites purulentes post-neurochirurgicales. Trente et une observations.