title: [Therapeutic prospects of new fluoroquinolones].
abstract: Fluoroquinolones are new synthetic derivatives with a broad spectrum and a potent antibacterial activity this permits to assimilate these molecules as antibiotics. These compounds are characterized by a quinoline or a naphthyridine nucleus with a fluorine atom in position 6 and a piperazine or a pyrrole nucleus in position 7. The combination of their antibacterial properties and the good absorption and tissue distribution allows their use in the treatment of the main infections caused by sensitive strains. The clinical and biological tolerance of these drugs are usually excellent.
mesh_terms: D000890:Anti-Infective Agents / Q000378:metabolism / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy*; D003550:Cystic Fibrosis / Q000188:drug therapy; D006801:Humans; D008171:Lung Diseases / Q000188:drug therapy; D008581:Meningitis / Q000188:drug therapy; D009287:Naphthyridines / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D018805:Sepsis / Q000188:drug therapy; D012749:Sexually Transmitted Diseases / Q000188:drug therapy
chemical_list: D000890:Anti-Infective Agents; D009287:Naphthyridines
vernacular_title: Perspectives thérapeutiques des nouvelles fluoroquinolones.