Specificity of esterases and structures of prodrug esters. III. Activity of rat tissue homogenates, rat plasma and porcine liver esterase for the hydrolysis of 3',5'-bis-dicarboxylic acid hemiesters of 5-fluoro-2'-deoxyuridine.
D000818:Animals; D003998:Dicarboxylic Acids / Q000378:metabolism; D004950:Esterases / Q000378:metabolism*; D004952:Esters / Q000378:metabolism; D005467:Floxuridine / Q000031:analogs & derivatives* / Q000378:metabolism; D006868:Hydrolysis; D066298:In Vitro Techniques; D008099:Liver / Q000201:enzymology*; D051381:Rats; D013379:Substrate Specificity; D013552:Swine
D003998:Dicarboxylic Acids; D004952:Esters; D005467:Floxuridine; D004950:Esterases