Flurbiprofen for the treatment of soft tissue trauma.
The use of flurbiprofen as an analgesic and anti-inflammatory agent in patients with soft tissue trauma induced by sports injuries, lumbar disk syndrome, or surgery was considered in three clinical trials. In the first study, soft tissue injuries to the lower limb in 51 professional soccer players were treated for six days with 150 mg of flurbiprofen per day or 3.6 g of aspirin per day. The second study compared three weeks of treatment with daily doses of 200 mg of flurbiprofen and 4 g of acetaminophen in 50 patients with acute low back pain. In the third study, 100 postoperative patients were given 400 mg of flurbiprofen per day or 4 g of acetaminophen per day for seven days following total or partial meniscectomy. In all of these trials, flurbiprofen showed excellent analgesic efficacy in reducing pain and swelling, and enhanced the recovery of patients with soft tissue trauma.
D000082:Acetaminophen / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D001416:Back Pain / Q000188:drug therapy; D005480:Flurbiprofen / Q000627:therapeutic use*; D006801:Humans; D007717:Knee / Q000601:surgery; D007869:Leg Injuries / Q000188:drug therapy*; D008023:Ligaments, Articular / Q000601:surgery; D010146:Pain / Q000188:drug therapy*; D010149:Postoperative Pain / Q000188:drug therapy; D011422:Propionates / Q000627:therapeutic use*
D011422:Propionates; D000082:Acetaminophen; D005480:Flurbiprofen; D001241:Aspirin