title: Risk for trisomy 21 in offspring of individuals who have relatives with trisomy 21.
abstract: This study was performed to determine if sibs and other relatives of individuals with trisomy 21 are themselves at increased risk for having offspring with trisomy 21. The results suggest that the reproductive risk to these relatives is not increased beyond the risk to the general population.
mesh_terms: D004314:Down Syndrome / Q000235:genetics*; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D008297:Male; D012306:Risk