title: Validation of a non-invasive method for localization of atherosclerotic occlusive disease in the legs.
abstract: The accuracy in determining the level of haemodynamically significant occlusive arterial disease (stenosis of greater than or equal to 50%) in the leg by a combination of segmental blood pressure measurements and evaluation of pulses with the Doppler shift technique was assessed in 50 patients (100 legs), using angiography as the reference method. For aorto-iliac disease the sensitivity was 72%, the specificity 97% and the diagnostic accuracy 87%. For femoro-popliteal disease the corresponding figures were 87%, 78% and 85%, respectively. The accuracy of a positive diagnosis was 93% for both levels. Similar results were obtained for combined aorto-iliac and femoro-popliteal disease. The accuracy in detecting calf disease was poor.
mesh_terms: D000368:Aged; D000792:Angiography; D001161:Arteriosclerosis / Q000175:diagnosis*; D001783:Blood Flow Velocity; D001795:Blood Pressure Determination; D005260:Female; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012212:Rheology