[Various indicators of hemostasis, plasminogen-plasmin and kinin systems of the blood and their inhibitors in patients with stable angina pectoris and post-infarction cardiosclerosis after graded physical load].
Combined assessment of some parameters related to hemostasis and blood plasminogen-plasmin and kinin systems and their inhibitors was carried out in 150 patients with stable angina and postinfarction cardiosclerosis during rationed exercise (bicycle ergometry). Patients with low stress tolerance showed considerably activated kallikrein-kinin system, depressed total fibrinolytic activity, elevated trypsin and enhanced platelet adhesive properties, while their inhibitor activities were reduced. Postmyocardial infarction patients showed a more dramatic increase in free kinins, coupled with depressed inhibitor proteinases and kininase activities, and a slight increment in fibrinolytic activity, as compared to patients having to history of myocardial infarction. The magnitude of free kinins and trypsin rise and kininase fall increases with age in these patients.
D000328:Adult; D000787:Angina Pectoris / Q000097:blood*; D003324:Coronary Artery Disease / Q000097:blood*; D005080:Exercise Test; D005341:Fibrinolysin / Q000032:analysis; D006487:Hemostasis; D006801:Humans; D007705:Kinins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications; D010958:Plasminogen / Q000032:analysis; D000515:alpha 1-Antitrypsin / Q000032:analysis*
D007705:Kinins; D000515:alpha 1-Antitrypsin; D010958:Plasminogen; D005341:Fibrinolysin
Nekotorye pokazateli gemostaza, plazminogen-plazminovoĭ, kininovoĭ sistem krovi i ikh ingibitorov u bol'nykh so stabil'noĭ stenokardieĭ i postinfarktnym kardiosklerozom v usloviiakh dozirovannoĭ fizicheskoĭ nagruzki.