[Surface membrane receptors, differentiation antigens and cytochemical characteristics of blood cells in acute lymphoblastic leukemia in children].
The study of surface membrane receptors by the methods of combined patch-formation and cytochemical markers of blast cells has revealed 57 cases of childhood ALL which were classified as non-T, non-B cell, pre-T, T- and B-cell forms. Using the panel of monoclonal antibodies (IKO-1, 02, 10, 11 and I10P-1-8) the surface differentiation antigens have been studied in certain patients. Significance of cytochemical studies for definition of main forms of acute leukemias and immunocytology for differentiation of some types of ALL was suggested.
D000293:Adolescent; D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm / Q000032:analysis; D000954:Antigens, Surface / Q000032:analysis; D001402:B-Lymphocytes / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007945:Leukemia, Lymphoid / Q000145:classification / Q000175:diagnosis* / Q000276:immunology; D015260:Neprilysin; D010641:Phenotype; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D000954:Antigens, Surface; D015260:Neprilysin
Retseptory poverkhnostnykh membran, differentsirovochnye antigeny i tsitokhimicheskie priznaki kletok krovi pri ostrom limfoblastnom leĭkoze u deteĭ.