[Genetic resistance to rabies infection. Trial of demonstrating the heritability of resistance to the infection (preliminary evaluation on a murine model)].
A model in mice was developed in order to check if a resistance against rabies could be naturally and genetically selected in a line of mammals. A more resistant strain of mice (DBA/2) was identified. However, up to present, all attempts have failed in view to create a resistant strain of swiss mice in breeding individuals surviving to rabies infection.
D000818:Animals; D007113:Immunity, Innate; D051379:Mice; D008815:Mice, Inbred Strains; D008817:Mice, Mutant Strains; D008819:Mice, Nude; D011818:Rabies / Q000235:genetics* / Q000276:immunology; D013045:Species Specificity
Résistance génétique à l'infection rabique. Essai de mise en évidence de l'héritabilité d'une résistance à l'infection (bilan préliminaire sur un modèle murin).