title: Molecular biology of atrial natriuretic peptides.
abstract: Recent identification of atrial natriuretic peptides (ANP) in the mammalian heart demonstrated that the heart functions not only as a pump impelling the blood but also as an endocrine organ that secretes the hormone controlling body fluid volume, electrolyte balance, and blood pressure. The biochemical features of the atrial natriuretic hormones now begin to emerge on the basis of the identification of ANP and the cloning of complementary DNA encoding their precursors in mammals. The current status of the molecular biology of ANP is reviewed.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D009320:Atrial Natriuretic Factor / Q000235:genetics; D004247:DNA / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D012689:Sequence Homology, Nucleic Acid
chemical_list: D009320:Atrial Natriuretic Factor; D004247:DNA