A cytogenetic survey of a mentally retarded school-age population with special reference to fragile sites.
A cytogenetic survey has been carried out among mentally retarded schoolchildren in the West Midlands Region, England. The conclusions are that the Fragile-X syndrome is second only to Down's syndrome as a cytogenetic entity contributing to mental handicap among children of school age.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002869:Chromosome Aberrations / Q000453:epidemiology*; D025063:Chromosome Disorders; D043283:Chromosome Fragile Sites; D002873:Chromosome Fragility; D004314:Down Syndrome / Q000453:epidemiology; D004739:England; D005260:Female; D005600:Fragile X Syndrome / Q000453:epidemiology; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics*; D008297:Male