Ultrastructural localization of bronchial inhibitor in human airways using protein A-gold technique.
Gold immunolabelling of human airways using a polyclonal antibody specific for the bronchial inhibitor (brI) demonstrates that this protease inhibitor is present in the serous cells of the bronchial glands. Most of the largest secretory granules (89%) are uniformly stained for brI whereas the smallest granules (diameter less than 80 nm) appear frequently (68%) devoid of brI.
D001344:Autopsy; D006046:Gold; D006801:Humans; D007202:Indicators and Reagents; D008168:Lung / Q000648:ultrastructure*; D008854:Microscopy, Electron; D011480:Protease Inhibitors / Q000032:analysis*; D011506:Proteins / Q000032:analysis*; D015843:Serpins; D013205:Staphylococcal Protein A; D014132:Trachea / Q000648:ultrastructure*
D007202:Indicators and Reagents; D011480:Protease Inhibitors; D011506:Proteins; D015843:Serpins; D013205:Staphylococcal Protein A; D006046:Gold