Sensitization to epichlorohydrin and epoxy system components.
In an epoxy resin manufacturing plant, 26 of 228 (11.4%) workers had work-related eruptions; 19 were patch tested. The test series consisted of chemicals used in the manufacturing process, a standard battery and some other sensitizers. The prevalence of sensitization to epichlorohydrin and/or epoxy resins in the whole group was 6.1%. A relatively high prevalence (3.5%) of epichlorohydrin sensitization was found. 10 cases of sensitization to liquid epoxy resin (MW about 385) were observed, in 7 cases combined with allergy to solid epoxy resin (MW 980). Sensitization to Bisphenol A was not seen.
D000328:Adult; D001559:Benzhydryl Compounds; D002728:Chlorohydrins / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000209:etiology* / Q000517:prevention & control; D009783:Dermatitis, Occupational / Q000209:etiology* / Q000517:prevention & control; D004811:Epichlorohydrin / Q000009:adverse effects*; D004853:Epoxy Resins / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D010636:Phenols / Q000009:adverse effects; D000098826:Bisphenol A Compounds
D001559:Benzhydryl Compounds; D002728:Chlorohydrins; D004811:Epichlorohydrin; D004853:Epoxy Resins; D010636:Phenols; C006780:bisphenol A; D000098826:Bisphenol A Compounds