title: [The need for hepatitis B immunoprevention in families with vertical hepatitis B infected children].
abstract: We investigated the scope of hepatitis B infection in 11 families (family contacts: fathers, siblings) in which the mother transmitted (vertical) hepatitis B infection to the child.
  
  
  RESULTS
  The initial examination demonstrated an acute hepatitis B infection in one of the 11 fathers and former hepatitis B infection in 8 fathers. In 2 fathers no hepatitis B markers were found (susceptible for hepatitis B). In 3 of the 10 siblings examined an acute hepatitis B infection was demonstrated, one child showed signs of a former hepatitis B infection, and in 6 no hepatitis B markers were demonstrable. Current checks made in 5 families over a period of about 6.2 years showed another hepatitis B infection in one father and one child. These observations stress the importance of immunisation in such families.
mesh_terms: D000328:Adult; D002648:Child; D005260:Female; D006509:Hepatitis B / Q000517:prevention & control* / Q000635:transmission; D006511:Hepatitis B Antigens / Q000032:analysis; D017325:Hepatitis B Vaccines; D006801:Humans; D007116:Immunization, Passive; D008297:Male; D014761:Viral Hepatitis Vaccines / Q000008:administration & dosage*
chemical_list: D006511:Hepatitis B Antigens; D017325:Hepatitis B Vaccines; D014761:Viral Hepatitis Vaccines
vernacular_title: Zur Notwendigkeit der Hepatitis-B-Immunprophylaxe in den Familien vertikal Hepatitis-B-infizierter Kinder.