Sulindac-associated small bowel lesion.
Diarrhea and a small bowel lesion similar to that reported in celiac sprue were observed in a patient who had been taking sulindac. Symptoms and biopsy abnormalities resolved completely after discontinuation of the medication and promptly recurred upon its re-administration. This report emphasizes the need to consider possible drug-related small bowel disease in the growing list of causes of the "flat" small intestinal mucosal lesion.
D001416:Back Pain / Q000188:drug therapy; D001706:Biopsy; D003967:Diarrhea / Q000139:chemically induced*; D004378:Duodenal Diseases / Q000139:chemically induced* / Q000473:pathology; D004386:Duodenum / Q000473:pathology; D005260:Female; D006801:Humans; D007192:Indenes / Q000009:adverse effects*; D008875:Middle Aged; D013467:Sulindac / Q000009:adverse effects* / Q000627:therapeutic use
D007192:Indenes; D013467:Sulindac