title: von Willebrand factor and platelet function.
abstract: The complex interactions of platelets, von Willebrand factor (VWF), and vascular endothelium have been explored by many investigators during the last decade. With the development of better methods to assess these components has come an increased recognition of diseases associated with defects in the platelet-VWF interaction. Moreover, alternative therapeutic approaches have become available for the clinician who treats patients with disorders of VWF function.
mesh_terms: D015119:Aminocaproic Acid / Q000627:therapeutic use; D000911:Antibodies, Monoclonal / Q000276:immunology; D001792:Blood Platelets / Q000502:physiology*; D001808:Blood Vessels / Q000378:metabolism; D003094:Collagen / Q000378:metabolism; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004587:Electrophoresis, Agar Gel; D005169:Factor VIII / Q000032:analysis; D005796:Genes; D006023:Glycoproteins / Q000378:metabolism; D006487:Hemostasis; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism; D010973:Platelet Adhesiveness; D010980:Platelet Membrane Glycoproteins; D011485:Protein Binding; D014842:von Willebrand Diseases / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy; D014841:von Willebrand Factor / Q000032:analysis / Q000235:genetics / Q000276:immunology / Q000378:metabolism / Q000502:physiology*
chemical_list: D000911:Antibodies, Monoclonal; D006023:Glycoproteins; D008565:Membrane Proteins; D010980:Platelet Membrane Glycoproteins; D014841:von Willebrand Factor; D005169:Factor VIII; D003094:Collagen; D003894:Deamino Arginine Vasopressin; D015119:Aminocaproic Acid