title: Diurnal beta-endorphin changes in human cerebrospinal fluid.
abstract: Plasma and cerebrospinal fluid (CSF) beta-endorphin levels were determined by a RIA method in seven hydrocephalic male patients. The samples were simultaneously collected every two hours from 8 AM to 12 midnight and every hour from 1 AM to 7 AM. In both plasma and CSF beta-endorphin levels showed significant time-related variations during the 24 hour period. These results suggest the existence of diurnal CSF beta-endorphin variations analogous to those observed in plasma.
mesh_terms: D000328:Adult; D002940:Circadian Rhythm; D004723:Endorphins / Q000097:blood / Q000134:cerebrospinal fluid*; D006801:Humans; D006849:Hydrocephalus / Q000097:blood / Q000134:cerebrospinal fluid*; D008297:Male; D008875:Middle Aged; D001615:beta-Endorphin
chemical_list: D004723:Endorphins; D001615:beta-Endorphin