Granulocyte function in patients with multiple sclerosis.
Peripheral blood granulocytes and sera from patients with relapsing/remittent (group I) and chronic progressive (group II) multiple sclerosis (MS) did not differ from control cells and sera with regard to the proportion of cells bearing receptors for Fc gamma and C3b; random or directed (chemotactic) motility of granulocytes; activation as measured by chemiluminescence; opsonic activity of sera. The results of this study suggest that granulocyte function in MS is normal.
D002465:Cell Movement; D002634:Chemotaxis, Leukocyte; D006098:Granulocytes / Q000276:immunology / Q000502:physiology*; D006801:Humans; D008163:Luminescent Measurements; D009103:Multiple Sclerosis / Q000145:classification / Q000276:immunology / Q000503:physiopathology*; D009895:Opsonin Proteins / Q000032:analysis; D011951:Receptors, Complement; D017463:Receptors, Complement 3b; D011961:Receptors, Fc; D017452:Receptors, IgG
D009895:Opsonin Proteins; D011951:Receptors, Complement; D017463:Receptors, Complement 3b; D011961:Receptors, Fc; D017452:Receptors, IgG