The disappearance of the foetal suppressor cell activity in newborn rats.
The suppressor splenocyte activity in newborn rats was studied using an intrarenal test of the local graft versus host reaction in the xenogenous rat-mouse system. It was demonstrated that the suppressor splenocyte activity in newborn rats born from both physiological and hormonally or mechanically prolonged pregnancy terminates within 2 days after birth. On the other hand, in newborn rats born from shortened pregnancy the suppressor splenocyte activity persists for 3 days.
D000818:Animals; D000831:Animals, Newborn; D005260:Female; D005333:Fetus / Q000276:immunology*; D006087:Graft vs Host Reaction; D007165:Immunosuppression Therapy; D007668:Kidney / Q000473:pathology; D051379:Mice; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology* / Q000637:transplantation