title: [Contact allergy to the antifungal agent naftifin].
abstract: Two patients treated topically against dermatophytes with a naftifine containing antifungal became allergic to the efficacious component naftifine. One of them also reacted to benzyl alcohol. Sensitization experiments in guinea pigs corroborated the suspicion that this allylamine is a contact sensitizer. To date, only few cases of allergic reactions to naftifine have been reported.
mesh_terms: D000293:Adolescent; D000328:Adult; D000499:Allylamine / Q000009:adverse effects* / Q000031:analogs & derivatives / Q000627:therapeutic use; D000588:Amines / Q000009:adverse effects*; D000935:Antifungal Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003881:Dermatomycoses / Q000188:drug therapy*; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D010328:Patch Tests
chemical_list: D000588:Amines; D000935:Antifungal Agents; D000499:Allylamine; C029178:naftifine
vernacular_title: Kontaktallergie auf das Antimykotikum Naftifin.