title: Atrial natriuretic polypeptide-like immunoreactivity in the rat pituitary: light and electron microscopic studies.
abstract: Immunoreactive atrial natriuretic polypeptide (ANP) was investigated in the pituitary of rats by light and electron microscopy using the indirect immunofluorescence and peroxidase-antiperoxidase techniques. ANP-like immunoreactivity was present in 30-35% of anterior pituitary cells. These cells have two types of secretory granules being characteristic of rat gonadotrophin-storing granules, and were usually adjacent to the capillary endothelium. The results of this study suggest the co-occurrence of ANP and gonadotrophins in the anterior pituitary cells.
mesh_terms: D000818:Animals; D009320:Atrial Natriuretic Factor / Q000032:analysis*; D003594:Cytoplasmic Granules / Q000032:analysis; D005455:Fluorescent Antibody Technique; D006065:Gonadotropins, Pituitary / Q000032:analysis; D007124:Immunoenzyme Techniques; D008297:Male; D008854:Microscopy, Electron; D010903:Pituitary Gland, Anterior / Q000032:analysis* / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D006065:Gonadotropins, Pituitary; D009320:Atrial Natriuretic Factor