Amino acid sequence of atrial natriuretic peptides in human coronary sinus plasma.
Two atrial natriuretic peptides were purified from pooled human coronary sinus plasma by Sep-Pak extraction, immunoaffinity chromatography and reverse phase HPLC. The amino acid sequences of the two peptides were homologous with 99-126 human atrial natriuretic peptide (hANP) and 106-126 hANP, the latter being most probably linked to 99-105 ANP by the disulphide bond. The molar ratio of the peptides in plasma, as assessed by radioimmunoassay was 10:3.
D000595:Amino Acid Sequence; D009320:Atrial Natriuretic Factor / Q000097:blood*; D002851:Chromatography, High Pressure Liquid; D006801:Humans; D010449:Peptide Mapping; D012850:Sinus of Valsalva
D009320:Atrial Natriuretic Factor