Hydroxamate production by Aquaspirillum magnetotacticum.
Spent culture fluids from Aquaspirillum magnetotacticum MS-1 grown at high (20 microM) but not low (5 microM) iron concentration contained material yielding a positive hydroxamate test. Cells possessed six major outer membrane proteins. Three outer membrane proteins ranging from 72,000 to 85,000 daltons were coordinately produced at iron concentrations conducive to hydroxamate production. A 55,000-dalton iron-repressible outer membrane protein was also present in strain MS-1 cultured at low but not high ferric quinate concentration. Culture fluids from strain MS-1 which were hydroxamate positive augmented growth of a Salmonella typhimurium siderophore-deficient (enb-7) mutant in low-iron medium, suggesting a role of hydroxamate in uptake of iron by the cell.
D001419:Bacteria / Q000378:metabolism*; D001425:Bacterial Outer Membrane Proteins / Q000096:biosynthesis; D005290:Ferric Compounds / Q000378:metabolism / Q000494:pharmacology; D006877:Hydroxamic Acids / Q000096:biosynthesis* / Q000494:pharmacology; D007502:Iron Chelating Agents / Q000096:biosynthesis; D008970:Molecular Weight; D011801:Quinic Acid / Q000378:metabolism / Q000494:pharmacology; D012486:Salmonella typhimurium / Q000254:growth & development; D017262:Siderophores
D001425:Bacterial Outer Membrane Proteins; D005290:Ferric Compounds; D006877:Hydroxamic Acids; D007502:Iron Chelating Agents; D017262:Siderophores; D011801:Quinic Acid