title: Hand eczema in hairdressers and nurses: a prospective study. I. Evaluation of atopy and nickel hypersensitivity at the start of apprenticeship.
abstract: A prospective study of the development of hand eczema was initiated in 86 junior hairdressers and 217 junior nurses. Data obtained at the start of their apprenticeships are presented. None of the junior apprentices presented with hand eczema, but a history of hand eczema was reported by 22/303 (7%) of the students. Almost half of this group (10/22, 45%) could be classified as atopics. Students without a history of hand eczema showed a similar frequency of atopy (17%) as observed in the general population. History of hand eczema was not related to nickel hypersensitivity, as assessed by patch testing. The incidence of nickel hypersensitivity was high in junior hairdressers (26%), compared to junior nurses (12%). Information as to previous contacts with nickel suggested that development of nickel allergy had been promoted by ear-piercing. A lower incidence of nickel hypersensitivity was observed if this potentially sensitizing event had been proceeded by orthodontic treatment with nickel-containing materials. This phenomenon is discussed in terms of orally-induced tolerance.
mesh_terms: D000293:Adolescent; D000328:Adult; D001505:Beauty Culture; D003876:Dermatitis, Atopic / Q000139:chemically induced*; D009783:Dermatitis, Occupational / Q000139:chemically induced*; D005260:Female; D006801:Humans; D009532:Nickel / Q000009:adverse effects*; D009726:Nurses; D009967:Orthodontic Appliances / Q000009:adverse effects; D011446:Prospective Studies
chemical_list: D009532:Nickel