title: Effect of sodium phosphonoformate on blood group antibody detection.
abstract: A panel of 47 blood group antibodies covering a range of blood group antigens has been tested in the presence of 680 mumol concentration sodium phosphonoformate as a putative chemical additive to serum to reduce infectivity of 'high risk' HTLV-III/HBsAg samples. No inhibitory effect could be demonstrated using the indirect antiglobulin test or prepapainized cell test.
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000097:blood; D000906:Antibodies / Q000032:analysis; D001788:Blood Grouping and Crossmatching; D003298:Coombs Test; D017245:Foscarnet; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006801:Humans; D009943:Organophosphorus Compounds / Q000494:pharmacology*; D010746:Phosphonoacetic Acid / Q000031:analogs & derivatives / Q000494:pharmacology*
chemical_list: D000906:Antibodies; D006514:Hepatitis B Surface Antigens; D009943:Organophosphorus Compounds; D017245:Foscarnet; D010746:Phosphonoacetic Acid