Synthesis of atriopeptin III by fragment condensation and solid phase synthesis.
The synthesis of Atriopeptin III (AP III) was accomplished using fragment condensation and solid phase synthesis with Fmoc-groups as temporary and tert.-butyl-groups as permanent protection. Advantages and disadvantages of both methods are discussed.
D009320:Atrial Natriuretic Factor / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D007202:Indicators and Reagents; D010446:Peptide Fragments; D012996:Solutions
D007202:Indicators and Reagents; D010446:Peptide Fragments; D012996:Solutions; D009320:Atrial Natriuretic Factor