Estimating kidney function during urography. Comparison of contrast medium clearance and simultaneous 51Cr-EDTA clearance.
Blood samples were taken from 21 subjects at 2 to 4 hours after simultaneous injection of contrast medium (metrizoate) for urography and 51Cr-EDTA. Clearance calculations were performed using the single injection (single slope) technique. The plasma concentrations of 51Cr-EDTA and contrast medium were measured by gamma counting and X-ray fluorescence analysis, respectively. A good correlation was found between the clearance of 51Cr-EDTA and clearance of contrast medium (r = 0.94).
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002860:Chromium Radioisotopes / Q000493:pharmacokinetics; D004492:Edetic Acid / Q000493:pharmacokinetics; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007463:Iodobenzoates; D008297:Male; D008657:Metabolic Clearance Rate; D008794:Metrizoic Acid / Q000031:analogs & derivatives / Q000493:pharmacokinetics; D008875:Middle Aged; D013052:Spectrometry, X-Ray Emission; D014567:Urography
D002860:Chromium Radioisotopes; D007463:Iodobenzoates; D004492:Edetic Acid; D008794:Metrizoic Acid; C021342:methylglucamine metrizoate