title: [Contact allergy to the preservative bronopol].
abstract: Six cases of contact allergy to bronopol are described (5 females, 1 male; mean age, 60.8 years). Four patients suffered from stasis dermatitis of the lower leg. The cause of sensitization has been traced to bronopol-containing ointments in 5 of 6 cases. For patch testing 0.25% bronopol in petrolatum is recommended. One-third of the patients were also sensitized to formaldehyde, which is a degradation product of bronopol.
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D010592:Pharmaceutic Aids; D011310:Preservatives, Pharmaceutical; D011409:Propylene Glycols / Q000009:adverse effects*
chemical_list: D010592:Pharmaceutic Aids; D011310:Preservatives, Pharmaceutical; D011409:Propylene Glycols; C006827:bronopol
vernacular_title: Kontaktallergie auf das Konservierungsmittel Bronopol.