title: Porokeratosis plantaris, palmaris, et disseminata. Report of a case and treatment with isotretinoin.
abstract: Porokeratosis plantaris, palmaris, et disseminata is a unique clinical entity characterized by the familial occurrence of multiple porokeratoses predominantly on the palms and soles but also on both sun-exposed and non-sun-exposed areas of the body. Since its original description in 1971 by Guss and colleagues, there has been only one other report of this syndrome. We have discovered a third family with this disorder and have used isotretinoin successfully to control the condition in one of the family's symptomatic members.
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D015474:Isotretinoin; D007645:Keratoderma, Palmoplantar / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D008297:Male; D008875:Middle Aged; D014212:Tretinoin / Q000627:therapeutic use*
chemical_list: D014212:Tretinoin; D015474:Isotretinoin