Immunologic aspects of bone transplantation. A rationale for future studies.
This article presents the hypothesis that bone, like other soft tissue, is rejected in an immunologic fashion. However, because bone is mineralized, it presents unique aspects that are also dealt with by the immune system. The article goes on to review the immunologic considerations of bone allograft reactivity.
D000818:Animals; D000954:Antigens, Surface / Q000276:immunology; D001853:Bone Marrow / Q000276:immunology; D001862:Bone Resorption / Q000276:immunology; D016025:Bone Transplantation; D001842:Bone and Bones / Q000276:immunology; D006084:Graft Rejection; D007166:Immunosuppressive Agents / Q000494:pharmacology; D008213:Lymphocyte Activation; D008285:Major Histocompatibility Complex; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology; D014181:Transplantation Immunology; D014184:Transplantation, Homologous
D000954:Antigens, Surface; D007166:Immunosuppressive Agents