title: Lithium therapy for affective disorders.
abstract: Lithium is effective in the treatment of bipolar disorder. Management of patients receiving prophylactic lithium therapy requires alertness to the development of neurologic, endocrine, cardiac and renal toxicity, as well as to dermatologic and gastrointestinal side effects. Lithium is involved in many drug interactions. Careful laboratory monitoring is essential, and treatment must be individualized.
mesh_terms: D000208:Acute Disease; D001714:Bipolar Disorder / Q000188:drug therapy*; D003866:Depressive Disorder / Q000188:drug therapy*; D004064:Digestive System / Q000187:drug effects; D003875:Drug Eruptions / Q000209:etiology; D005260:Female; D006321:Heart / Q000187:drug effects; D006801:Humans; D007668:Kidney / Q000187:drug effects / Q000378:metabolism; D007700:Kinetics; D007774:Lactation; D008094:Lithium / Q000009:adverse effects / Q000378:metabolism / Q000627:therapeutic use*; D008991:Monitoring, Physiologic; D011247:Pregnancy; D012559:Schizophrenia / Q000188:drug therapy; D014202:Tremor / Q000139:chemically induced
chemical_list: D008094:Lithium