Ectopic ACTH production by a thymic carcinoid tumour.
An ACTH-producing thymic carcinoid tumour was diagnosed in a 10-year-old girl, 8 years after bilateral adrenalectomy for Cushing's syndrome. The peptides produced by the tumour were characterised thoroughly. High circulating levels of beta-endorphin and other peptides may have contributed to mood and behaviour disturbances.
D000182:ACTH Syndrome, Ectopic / Q000097:blood / Q000378:metabolism*; D002276:Carcinoid Tumor / Q000097:blood / Q000378:metabolism*; D002648:Child; D003480:Cushing Syndrome / Q000097:blood / Q000209:etiology; D005260:Female; D006801:Humans; D009384:Paraneoplastic Endocrine Syndromes / Q000378:metabolism*; D011188:Potassium / Q000097:blood; D013953:Thymus Neoplasms / Q000097:blood / Q000378:metabolism*; D001615:beta-Endorphin / Q000097:blood
D001615:beta-Endorphin; D011188:Potassium