title: [Prevention of viral hepatitis in children with concentrated human leukocyte interferon].
abstract: Concentrated human leukocytic interferon, introduced electrophoretically in small doses for preventive purposes, reduces morbidity rate in hepatitis foci 6 times, probably due to an increase in the production of endogenous interferon. Interferon is introduced once in 7-10 days, taking into account the minimal time of the preservation of the preparation in the musculocutaneous depot. The application of a rubber bandage and the creation of the zone of congestive hyperemia leads to deeper penetration of interferon and to the increased therapeutic effectiveness of the preparation. The absence of significant differences in a number of immunological characteristics may be attributed to the use of interferon for the prophylaxis of healthy children having had contacts with viral hepatitis patients rather than children, actually having the disease.
mesh_terms: D000293:Adolescent; D002648:Child; D004197:Disease Reservoirs; D006525:Hepatitis, Viral, Human / Q000453:epidemiology / Q000517:prevention & control*; D006801:Humans; D007370:Interferon Type I / Q000008:administration & dosage*; D007478:Iontophoresis / Q000379:methods; D012426:Russia; D013848:Thigh; D013997:Time Factors; D014505:Urban Population
chemical_list: D007370:Interferon Type I
vernacular_title: Profilaktika virusnogo gepatita u deteĭ chelovecheskim kontsentrirovannym leĭkotsitarnym interferonom.