title: Chemonucleolysis as an alternative to laminectomy for the herniated lumbar disc. Experience with patients in a private orthopedic practice.
abstract: Three hundred thirty-five patients with herniated lumbar intervertebral discs were injected with chymopapain. The overall success rate was 76%. The success rate was higher for private insurance patients (89%) than for Worker's Compensation patients (66%). There were no serious complications and patients spent fewer days in the hospital and returned to work faster than patients with laminectomies. Chemonucleolysis is an excellent alternative to open surgery for treatment of a herniated lumbar disc, especially if patients are selected carefully and good technique is strictly followed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002917:Chymopapain / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007348:Insurance, Health; D007404:Intervertebral Disc Chemolysis / Q000191:economics; D007405:Intervertebral Disc Displacement / Q000188:drug therapy*; D007796:Laminectomy; D007902:Length of Stay; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D014942:Workers' Compensation
chemical_list: D002917:Chymopapain