[Arthus reaction and delayed hypersensitivity reaction to nerve-specific proteins S-100 and 10-40-4 in schizophrenic patients].
Using cutaneous allergic tests, the authors studied the body sensitization of schizophrenic patients to neurospecific proteins S-100 and 10-40-4. The group under study included 27 subjects: 15 schizophrenics and 12 healthy subjects. There were statistically significant differences in manifestations of Arthus' reaction and delayed type hypersensitivity reaction to these proteins in the patients versus the normal subjects. The data obtained indicate the participation of proteins S-100 and 10-40-4 in the development of the immunopathological component in mental diseases.
D000328:Adult; D000941:Antigens / Q000276:immunology; D001183:Arthus Reaction / Q000150:complications*; D001253:Astrocytes / Q000276:immunology; D001327:Autoimmune Diseases; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000150:complications*; D008297:Male; D009419:Nerve Tissue Proteins / Q000276:immunology*; D009474:Neurons / Q000276:immunology; D009418:S100 Proteins / Q000276:immunology; D012559:Schizophrenia / Q000150:complications* / Q000276:immunology; D012867:Skin / Q000276:immunology
D000941:Antigens; D009419:Nerve Tissue Proteins; D009418:S100 Proteins; C484014:neurospecific brain antigen 10-40-4, human
Reaktsiia Artiusa i reaktsiia zamedlennoĭ giperchuvstvitel'nosti k neĭrospetsificheskim belkam S-100 i 10-40-4 u bol'nykh shizofrenieĭ.