A computerised tomographic study in DSM-III affective disorders.
The relationship between ventricular brain ratio (VBR) and clinical variables was investigated in 21 DSM-III depressed patients. None of the following dichotomies--major depression vs. dysthymic disorder, suicidal vs. non-suicidal patients, male vs. female patients--showed any statistically significant differences. An association was identified between VBR and age at onset of depression but when current age was controlled such an association failed to reach a statistically significant level except in the group with major depression. When patients were matched with a control group no differences in VBR were seen with age controlled by decade.
D000328:Adult; D000367:Age Factors; D001921:Brain / Q000473:pathology*; D002552:Cerebral Ventricles / Q000473:pathology*; D003866:Depressive Disorder / Q000150:complications / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D012737:Sex Factors; D013406:Suicide, Attempted; D014057:Tomography, X-Ray Computed