title: The increased COMT activity in Down syndrome patients is not a consequence of dosage effect owing to location of the gene on chromosome 21: further evidence.
mesh_terms: D000818:Animals; D002394:Catechol O-Methyltransferase / Q000235:genetics*; D002874:Chromosome Mapping; D002904:Chromosomes, Human, 21-22 and Y; D004314:Down Syndrome / Q000201:enzymology*; D006801:Humans; D006822:Hybrid Cells; D051379:Mice
chemical_list: D002394:Catechol O-Methyltransferase