Subacute sclerosing panencephalitis and progressive multiple sclerosis: T cell subsets in blood and CSF.
We studied the distribution of T, T helper (TH), and T suppressor (TS) cells in blood and CSF using an immunoperoxidase slide assay and monoclonal antibodies. In subacute sclerosing panencephalitis, we found an elevated level of TS and a decreased level of TH cells in both CSF and blood. In MS, the TH/TS ratio was increased.
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000276:immunology*; D013344:Subacute Sclerosing Panencephalitis / Q000276:immunology*; D013601:T-Lymphocytes / Q000032:analysis*; D006377:T-Lymphocytes, Helper-Inducer / Q000032:analysis*; D050378:T-Lymphocytes, Regulatory / Q000032:analysis*