Osteoradionecrosis: a study of the incidence in the North West of England.
A retrospective survey of 200 patients was carried out to determine the incidence of osteoradionecrosis in the North West of England. The patients all had been treated with radiotherapy for squamous cell carcinoma of the oral cavity. An overall incidence of osteoradionecrosis of 19.6% was found. Cases were designated as having major, moderate or minor osteoradionecrosis. The incidence of major osteoradionecrosis was 8%. Hemimandibulectomy was required for management of the necrosis in 3%. Factors involved in the aetiology are discussed.
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy; D004739:England; D005260:Female; D006801:Humans; D007571:Jaw Diseases / Q000453:epidemiology*; D007575:Jaw, Edentulous; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology / Q000532:radiotherapy; D010025:Osteoradionecrosis / Q000453:epidemiology*; D011832:Radiation Injuries / Q000453:epidemiology*; D012189:Retrospective Studies