title: [Isolated trisomy 21 in blasts of an acute lymphoblastic leukemia].
abstract: A two years and four months old boy without evidence of Down's syndrome exhibited a trisomy 21 in his acute lymphoblastic leucemic cells. During remission this chromosomal change disappeared. The cytogenetic examination of malignant cells serves an important tool in diagnosis and follow-up of acute leucemia as well as bone marrow transplantation.
mesh_terms: D001853:Bone Marrow / Q000473:pathology; D002675:Child, Preschool; D004314:Down Syndrome / Q000235:genetics*; D006801:Humans; D007124:Immunoenzyme Techniques; D007621:Karyotyping; D007945:Leukemia, Lymphoid / Q000175:diagnosis / Q000235:genetics*; D008297:Male
vernacular_title: Isolierte Trisomie 21 in Blasten einer akuten lymphoblastischen Leukämie.