[Interstitial lymphoid pneumonia and polyadenopathies in patients infected with the LAV/HTLV III virus].
Seven patients of Haitian and Central African origin were investigated for interstitial pneumonitis and unexplained chronic lymphadenopathy. A study of broncho-alveolar lavage fluid showed no opportunistic micro-organisms and disclosed a high alveolar lymphocyte count with more than 80% T8+ cells. In 3 patients, open lung biopsy showed lymphoid interstitial pneumonitis. Follicular hyperplasia was a constant finding in lymph nodes. Benign lymphocytic infiltration was found in other organs of all patients, associated with polyclonal hyperimmunoglobulinaemia, low peripheral T4+ cell count and LAV-Ig G antibodies.
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000276:immunology; D000328:Adult; D000350:Africa, Central / Q000208:ethnology; D044383:Black People; D005260:Female; D005602:France; D006205:Haiti / Q000208:ethnology; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008206:Lymphatic Diseases / Q000209:etiology*; D008297:Male; D011650:Pulmonary Alveoli / Q000473:pathology; D011658:Pulmonary Fibrosis / Q000000981:diagnostic imaging / Q000209:etiology*; D011859:Radiography; D013601:T-Lymphocytes / Q000145:classification; D013997:Time Factors
Pneumonie lymphoïde interstitielle et polyadénopathies chez des sujets infectés par le virus LAV/HTLV III.