title: Current treatment of dermatophytoses.
abstract: There is a wide variety of highly effective topical antifungal agents available for the treatment of dermatophytosis. In more widespread infections or those involving hair or nails oral therapy with griseofulvin or ketoconazole can be used. With both forms of therapy certain types of dermatophyte infection are clinically resistant to treatment. These include onychomycosis, infections of the sole caused by T.rubrum and certain forms of tinea capitis (e.g. favus) or tinea corporis. In future consideration needs to be given to find the optimum duration and frequency of treatment and better methods of allowing penetration of drugs into nails and heavely keratinised sites.
mesh_terms: D000284:Administration, Oral; D000287:Administration, Topical; D006118:Griseofulvin / Q000627:therapeutic use; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use; D007654:Ketoconazole / Q000627:therapeutic use; D014009:Onychomycosis / Q000188:drug therapy; D010647:Phenyl Ethers / Q000627:therapeutic use; D014005:Tinea / Q000188:drug therapy*; D014006:Tinea Capitis / Q000188:drug therapy; D014008:Tinea Pedis / Q000188:drug therapy; D014047:Tolnaftate / Q000627:therapeutic use
chemical_list: D007093:Imidazoles; D010647:Phenyl Ethers; D014047:Tolnaftate; D006118:Griseofulvin; C100276:haloprogin; D007654:Ketoconazole