Pulmonary embolism after short-term treatment of acne vulgaris with ovulation suppressor agents.
A case of recurrent pulmonary embolism with infarction is described. The patient, a 28-year-old woman, had been treated over a four-month period with a preparation of cyproterone acetate plus ethinyloestradiol for acne vulgaris. It is suggested that the use of oral contraceptive preparations for the treatment of innocent disorders should be avoided when factors that may potentiate a thrombogenic effect are present.
D000152:Acne Vulgaris / Q000188:drug therapy*; D000328:Adult; D003534:Cyproterone / Q000009:adverse effects*; D017373:Cyproterone Acetate; D004338:Drug Combinations / Q000009:adverse effects; D004997:Ethinyl Estradiol / Q000009:adverse effects*; D005260:Female; D006801:Humans; D011655:Pulmonary Embolism / Q000097:blood / Q000139:chemically induced*; D012907:Smoking
D004338:Drug Combinations; D004997:Ethinyl Estradiol; D017373:Cyproterone Acetate; C032640:Cyproterone acetate, ethinyl estradiol drug combination; D003534:Cyproterone