Reliability of continuous-wave Doppler probes.
Small-diameter, thin-walled latex tubes, through which a blood-simulating agent (0.1% suspension of simethicone in 0.9% sodium chloride) flowed at controlled rates, were embedded at varying depths in a tissue-mimicking matrix of powered graphite suspended in 4% agar. A continuous-wave (CW) Doppler probe was mounted at a 45-degree angle to the flow and passed transversely over the tube by a motorized drive mechanism at a rate of 0.42 mm/sec. Flow rates through the tubes were monitored with electromagnetic flow probes. The maximum depth from which quantitatively reliable signals could be obtained was 1.2 cm for 10 MHz probes and 3.3 cm for 5 MHz probes. Qualitative detection of flow was possible to a depth of 3.1 cm for 10 MHz probes and 7.0 cm for 5 MHz probes. The distances from the tube center for obtaining quantitatively reliable signals were limited to +/- 0.9 mm with a 10 MHz probe and +/- 1.8 mm with a 5 MHz probe. Qualitatively useful signals could be detected +/- 2.9 mm from the beam center by the 10 MHz probes and +/- 4.4 mm by the 5 MHz probes indicating a need for cautious interpretation as an interfering signal might be generated by any vessel within that range. Twenty percent of the randomly tested CW probes were considered unsuitable for use in quantitating blood flow, which underscores the importance of probe characterization before use.
D001783:Blood Flow Velocity; D006801:Humans; D008961:Models, Structural; D012212:Rheology / Q000592:standards*