[Results of a study of the effectiveness of simultaneous immunization against influenza with live and inactivated vaccines (1980-1983)].
A comparative evaluation of immunological and epidemiological effectiveness of commercial live and killed vaccine preparations used simultaneously or separately was first carried out in simultaneous field trials of various methods of influenza vaccine prevention in a human population of 10,449 subjects. The advantage of simultaneous immunization was confirmed by immunological parameters and protective effect in the period of influenza A epidemic of 1983. The correlation of immunological and epidemiological effectiveness of influenza vaccines in joint or separate administration is discussed.
D000041:Absenteeism; D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D002986:Clinical Trials as Topic; D006801:Humans; D007114:Immunization / Q000379:methods*; D009980:Influenza A virus / Q000276:immunology; D007252:Influenza Vaccines / Q000276:immunology*; D007251:Influenza, Human / Q000453:epidemiology / Q000517:prevention & control*; D012426:Russia; D012621:Seasons; D014613:Vaccines, Attenuated / Q000276:immunology
D000914:Antibodies, Viral; D007252:Influenza Vaccines; D014613:Vaccines, Attenuated
Itogi izucheniia éffektivnosti odnovremennoĭ immunizatsii protiv grippa zhivoĭ i inaktivirovannoĭ vaktsinami (1980-1983 gg.).