Contact dermatitis to semisynthetic penicillins in factory workers.
45 workers developed dermatitis after handling semi-synthetic penicillins in a factory. All reacted on patch test, but several agents had to be used. Only 7 reacted to benzyl penicillin. 1/3 reacted to only one allergen, while 2/3 reacted to several. The duration of exposure before symptoms was short, often less than 2 months. 19 had hay fever or asthma, and they developed their symptoms after a shorter exposure time. A survey for airborne antibiotics was performed.
D000395:Air Pollutants, Occupational / Q000009:adverse effects; D003877:Dermatitis, Contact / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000139:chemically induced*; D004345:Drug Industry; D006801:Humans; D010328:Patch Tests; D010406:Penicillins / Q000009:adverse effects* / Q000138:chemical synthesis
D000395:Air Pollutants, Occupational; D010406:Penicillins