Molecular modeling and enzyme kinetics indicate a novel mechanism for mammalian 5-lipoxygenase.
D000818:Animals; D001094:Arachidonate 5-Lipoxygenase / Q000378:metabolism*; D001091:Arachidonate Lipoxygenases / Q000378:metabolism*; D001665:Binding Sites; D003198:Computer Simulation; D004220:Disulfides / Q000494:pharmacology; D004583:Electrons; D007700:Kinetics; D016859:Lipoxygenase Inhibitors; D008958:Models, Molecular; D010084:Oxidation-Reduction
D004220:Disulfides; D016859:Lipoxygenase Inhibitors; C053871:diphenyl disulfide; D001091:Arachidonate Lipoxygenases; D001094:Arachidonate 5-Lipoxygenase