title: Multiple system reaction to trimethoprim-sulfamethoxazole.
abstract: Trimethoprim-sulfamethoxazole may cause life-threatening reactions and even death, but such reactions are rare and do not detract from its usefulness. As with any therapy, however, caution should be observed in its use in children, and especially in the elderly.
mesh_terms: D000890:Anti-Infective Agents / Q000009:adverse effects*; D002648:Child; D003873:Dermatitis, Exfoliative / Q000139:chemically induced*; D004338:Drug Combinations / Q000009:adverse effects; D006801:Humans; D008297:Male; D009395:Nephritis, Interstitial / Q000139:chemically induced*; D011658:Pulmonary Fibrosis / Q000139:chemically induced*; D013420:Sulfamethoxazole / Q000009:adverse effects*; D014295:Trimethoprim / Q000009:adverse effects*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
chemical_list: D000890:Anti-Infective Agents; D004338:Drug Combinations; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim; D013420:Sulfamethoxazole