A summertime peak of Down's syndrome in Franklin County, Ohio.
In June, July, and August of 1984, more infants than usual were born with Down's syndrome in Franklin County, Ohio. A direct physician survey was done, and chromosome reports were reviewed, resulting in the identification of 11 infants with Down's syndrome born during that period. Using a chi 2 analysis, the expected number of affected newborns was five, making the actual number of 11 significant. Although a summertime peak was observed, the yearly incidence of 1.09 per 1000 live births was within the expected range.
D000293:Adolescent; D000328:Adult; D004314:Down Syndrome / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008423:Maternal Age; D009820:Ohio; D012621:Seasons