title: [Regulation of coronary circulation in patients with hypertensive cardiopathy: role of ventricular mechanoreceptors].
abstract: In order to assess the involvement of the cardiopulmonary receptors in the regulation of the coronary circulation, changes in coronary resistance produced by the application of a -10 mmHg pressure to the lower body were studied in 6 healthy subjects and 6 patients with arterial hypertension and left ventricular hypertrophy. The results show that the inhibition of the ventricular receptors significantly increases coronary resistance and that this reflex response is eliminated in hypertensive patients with ventricular hypertrophy. The results show that the inhibition of the ventricular receptors significantly increases coronary resistance and that this reflex response is eliminated in hypertensive patients with ventricular hypertrophy.
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D006332:Cardiomegaly / Q000503:physiopathology*; D003326:Coronary Circulation; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology*; D008297:Male; D008465:Mechanoreceptors / Q000503:physiopathology*; D011312:Pressure; D011433:Propranolol / Q000627:therapeutic use; D014655:Vascular Resistance / Q000187:drug effects
chemical_list: D011433:Propranolol
vernacular_title: La regolazione della circolazione coronarica nel paziente con cardiopatia ipertensiva: ruolo dei meccanocettori ventricolari.