[Post-translational modifications of various polypeptides in relation to the first mitosis in BALB/c mouse ova].
After X-irradiation at pronuclear stage, mice eggs from certain strains are reversibly blocked in G2 phase of the first cell cycle. However, evolution of polypeptide synthesis takes place in a normal way, except for three polypeptides sets of 30, 35 and 45 kd molecular weight that appear in dividing controls and not in blocked, irradiated eggs. It is shown that those first mitosis-specific polypeptides result from post-translational modifications, involving phosphorylations.
D000818:Animals; D006063:Chorionic Gonadotropin / Q000494:pharmacology; D004591:Electrophoresis, Polyacrylamide Gel; D051379:Mice; D008807:Mice, Inbred BALB C; D008938:Mitosis / Q000528:radiation effects; D010063:Ovum / Q000166:cytology*; D010455:Peptides / Q000235:genetics* / Q000302:isolation & purification; D011499:Protein Processing, Post-Translational / Q000528:radiation effects
D006063:Chorionic Gonadotropin; D010455:Peptides
Modifications post-traductionnelles de certains polypeptides en relation avec la première mitose chez l'oeuf de souris BALB/c.