Neuropathology and clinical practice in mental handicap.
Neuropathological examination of post-mortem material in cases of mental handicap may give valuable clues to aetiology, natural history and the effects of long-term medication. The dating of neuropathological changes may have implications for treatment and parental counselling. A coordinated procedure to obtain such information in a routine manner is recommended. Feedback to nursing and medical staff underlines the importance of this work. Such a procedure has been instituted in Ely Hospital and the results from the first 12-month period are reported.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001921:Brain / Q000473:pathology*; D002540:Cerebral Cortex / Q000002:abnormalities; D004314:Down Syndrome / Q000473:pathology; D005260:Female; D006801:Humans; D002534:Hypoxia, Brain / Q000473:pathology; D008607:Intellectual Disability / Q000209:etiology / Q000473:pathology*; D008297:Male; D008875:Middle Aged