[Gamma-irradiation induces in HeLa cells radioresistant DNA synthesis].
Cells of a suspension HeLa culture at the logarithmic phase of growth were exposed to 60Co-gamma-rays (5 Gy), incubated in the nutritious medium, and in 4 h subjected to repeated irradiation: the dose-response function and the dynamics of DNA synthesis inhibition were determined. It was shown that DNA synthesis was inhibited to a lesser extent after preirradiation, in other words, DNA synthesis was radioresistant. A correlation between this synthesis and reproductive cell death is discussed.
D004247:DNA / Q000187:drug effects / Q000528:radiation effects*; D004249:DNA Damage; D004261:DNA Replication / Q000187:drug effects / Q000528:radiation effects*; D005467:Floxuridine / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D011836:Radiation Tolerance
D005467:Floxuridine; D004247:DNA
Gamma-obluchenie indutsiruet v kletkakh HeLa radiorezistentnyĭ sintez DNK.