[Epidermoid cancer of the rumen induced in the C3H mouse by 7-methoxy-2-nitronaphto (2,1-b)furan (R7000)].
Nitro naphtofurans are powerful mutagenic agents. Subcutaneous injections of 7-methoxy 2-nitro naphtho [2,1-b] furan (R 7000) in C3H mice induce subcutaneous fibrosarcomas at the site of injection and squamous cell carcinomas of the stomach.
D000818:Animals; D002273:Carcinogens; D002294:Carcinoma, Squamous Cell / Q000139:chemically induced*; D005354:Fibrosarcoma / Q000139:chemically induced; D051379:Mice; D008809:Mice, Inbred C3H; D009581:Nitrofurans; D010212:Papilloma / Q000139:chemically induced; D013274:Stomach Neoplasms / Q000139:chemically induced*
D002273:Carcinogens; D009581:Nitrofurans; C030911:2-nitro-7-methoxynaphtho(2-1b)furan
Cancer épidermoïde du rumen induit chez la Souris C3H par le méthoxy-7 nitro-2 naphto [2,1-b] furanne (R 7000).