Are acrosyringia involved in the pathogenesis of "dyshidrosis"?
Investigations of dyshidrotic eruptions of various causes were done by conventional and electron microscopy. In all cases, the histological patterns were identical. The dyshidrotic vesicle is an intraepidermal, spongiotic lesion. The intraepidermal part of the eccrine sweat duct (acrosyringium) is not altered even by spongiosis. As the acrosyringium does not take part in formation of a dyshidrotic vesicle, the term "dyshidrosis" has to be regarded as a misnomer. Dyshidrosis is nothing but spongiotic dermatitis modified by the distinctive characteristics of palmar and plantar skin.
D004439:Eccrine Glands / Q000648:ultrastructure*; D011146:Eczema, Dyshidrotic / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D012867:Skin / Q000648:ultrastructure*; D013543:Sweat Gland Diseases / Q000473:pathology*; D013545:Sweat Glands / Q000648:ultrastructure*