Pharmacological manipulation of sexual behaviour in stallions.
Series of experiments and clinical trials were conducted to evaluate the effects of psychoneurotropic agents on sexual behaviour of stallions. The benzodiazepine derivative, diazepam (Valium), effectively reversed experimentally suppressed precopulatory arousal and response. Diazepam treatment also blocked the negative effect of novel environment on sexual response. The dibenzazepines imipramine and clomipramine induced erection, masturbation, and ejaculation in the absence of a sexual stimulus.
D000818:Animals; D002997:Clomipramine / Q000494:pharmacology*; D003975:Diazepam / Q000494:pharmacology*; D004542:Ejaculation / Q000187:drug effects; D010134:Fenclonine / Q000494:pharmacology; D006736:Horses / Q000502:physiology*; D007099:Imipramine / Q000494:pharmacology*; D008297:Male; D009270:Naloxone / Q000494:pharmacology; D010410:Penile Erection / Q000187:drug effects; D010906:Pituitary Hormone-Releasing Hormones / Q000494:pharmacology; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D015016:Yohimbine / Q000494:pharmacology
D010906:Pituitary Hormone-Releasing Hormones; D015016:Yohimbine; D009270:Naloxone; D002997:Clomipramine; D007099:Imipramine; D003975:Diazepam; D010134:Fenclonine