[Is protein C deficiency responsible for portal thrombosis after neonatal exchange transfusion?].
The authors report the case of a 12-year old boy admitted to hospital for cerebral ischaemic accident and in whom laboratory examinations revealed a 40% deficiency of protein C. Other investigations showed that the child, who had undergone exchange transfusion by the umbilical route at birth, had portal vein thrombosis. It is suggested that protein C deficiency might be responsible for some cases of portal vein thrombosis occurring after umbilical catheterization performed in the neonatal period.
D002404:Catheterization / Q000009:adverse effects; D002648:Child; D005078:Exchange Transfusion, Whole Blood / Q000009:adverse effects*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011169:Portal Vein; D020151:Protein C Deficiency; D013927:Thrombosis / Q000209:etiology*; D014471:Umbilical Veins
Le déficit en protéine C est-il responsable des thromboses portales après exsanguino-transfusion néo-natale?