Irritant dermatitis from tri-butyl tin oxide and contact allergy from chlorocresol.
A shipwright developed a delayed bullous irritant dermatitis from contact with a bis-tri-butyl tin oxide (TBTO) containing antifouling paint. He subsequently developed sensitization to 4-chloro-m-cresol, a constituent of a steroid cream. No cross sensitivity to 4-chloro-3,5 xylenol was seen. Low concentrations of 4-chloro-m-cresol in pet. may elicit a true positive reaction. TBTO is a strong irritant which will produce delayed bullous reactions in industrial use and on patch testing at 0.1% aqueous.
D000328:Adult; D003408:Cresols / Q000009:adverse effects* / Q000627:therapeutic use; D003877:Dermatitis, Contact / Q000188:drug therapy / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000139:chemically induced* / Q000188:drug therapy; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008297:Male; D010328:Patch Tests; D014220:Trialkyltin Compounds / Q000009:adverse effects*
D003408:Cresols; D014220:Trialkyltin Compounds; C005961:bis(tri-n-butyltin)oxide; C006984:chlorocresol