[Effect of cardioactive compounds on myocardial actomyosin in the centrifuged rat].
It has been shown that during centrifugation the modulating effect of cardioactive compounds, particularly adrenalin and obsidan, varies in similarity to that of Ca ions. The reactivity of the native actomyosin complex of the heart of white rats to such agents declines during centrifugation. This may be associated with changes in regulatory protein components through which the modulating effect of the above compounds is mediated. Differences in the reactivity to adrenalin and obsidan that persist after 2-month readaptation can be attributed to the heterogeneous recovery of properties of individual subunits of regulatory proteins.
D000205:Actomyosin / Q000378:metabolism*; D000222:Adaptation, Physiological; D000818:Animals; D017301:Ca(2+) Mg(2+)-ATPase / Q000378:metabolism; D002498:Centrifugation; D004837:Epinephrine / Q000494:pharmacology*; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D011433:Propranolol / Q000494:pharmacology*; D011506:Proteins / Q000378:metabolism; D051381:Rats
D011506:Proteins; D000205:Actomyosin; D011433:Propranolol; D017301:Ca(2+) Mg(2+)-ATPase; D004837:Epinephrine
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