[Two anti-Brucella SF311 and S480 monoclonal antibodies with protective activity against Brucella pathogenic for mice].
Two "protective" monoclonal anti-Brucella antibodies are described (SF311-IgG2a and S480-IgA) both of them accelerate the blood clearance of i.v. inoculated Brucella suis 1330 and decrease murine splenic infection on day 7.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000032:analysis / Q000627:therapeutic use*; D002002:Brucella / Q000472:pathogenicity*; D002006:Brucellosis / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D008214:Lymphocytes / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D008815:Mice, Inbred Strains; D010954:Plasmacytoma / Q000276:immunology
D000911:Antibodies, Monoclonal
Deux anticorps monoclonaux anti-Brucella SF311 et S480 possèdent une activité protectrice vis-à-vis de Brucella pathogènes pour la souris.