[Androgen receptors in the epithelium during prostatic gland induction from the urogenital sinus epithelium in Tfm-mutant mice].
Epithelio-mesenchymal recombination experiments revealed that urogenital-sinus mesenchyme of normal rat fetuses failed to induce androgen-receptors in sinus epithelium of androgen insensitive Tfm (testicular ferminization) mouse fetuses. Nevertheless, the mesenchyme can induce the morphogenesis of prostate-like glands in the androgen-receptor-deficient epithelium.
D013734:Androgen-Insensitivity Syndrome; D000818:Animals; D002454:Cell Differentiation; D005314:Embryonic and Fetal Development; D004848:Epithelium / Q000378:metabolism; D005260:Female; D008297:Male; D051379:Mice; D008817:Mice, Mutant Strains; D011247:Pregnancy; D011467:Prostate / Q000196:embryology* / Q000378:metabolism; D011944:Receptors, Androgen / Q000378:metabolism*; D013739:Testosterone / Q000378:metabolism
D011944:Receptors, Androgen; D013739:Testosterone
Récepteurs d'androgènes de l'épithélium au cours de l'induction des glandes prostatiques à partir de l'épithélium du sinus urogénital de la souris Tfm-mutant.