[Dexamethasone test: suppressors and non-suppressors, what's the difference?].
In sixty-six depressed in-patients, 20 of them showed marked resistance to suppression after dexamethasone. The authors found no difference between the two subgroups of suppressors and non suppressors, when considering the following parameters: age, sex, duration of illness, number of prior episodes, family history, intensity of depression, response to antidepressant treatment, relapses, diagnoses. Furthermore the normalization of DST after a 28 day treatment did not systematically correlate with a good clinical improvement.
D000639:Amitriptyline / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000627:therapeutic use; D002997:Clomipramine / Q000627:therapeutic use; D003866:Depressive Disorder / Q000188:drug therapy / Q000503:physiopathology*; D003907:Dexamethasone; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D009661:Nortriptyline / Q000627:therapeutic use; D010091:Oximes / Q000627:therapeutic use; D010913:Pituitary-Adrenal System / Q000503:physiopathology*; D015031:Zimeldine / Q000627:therapeutic use
D000928:Antidepressive Agents; D010091:Oximes; D000639:Amitriptyline; D015031:Zimeldine; C020724:clovoxamine; D003907:Dexamethasone; D009661:Nortriptyline; D002997:Clomipramine; D006854:Hydrocortisone
Test à la dexaméthasone: suppresseurs et non suppresseurs, quelle différence?