Tretinoin in the preoperative and postoperative management of dermabrasion.
Full-face or half-face dermabrasions for acne scarring were performed in 123 patients, 88 of whom received pretreatment for at least 2 weeks with 0.05% tretinoin cream. In the group that received tretinoin, healing, as evidenced by reepithelialization, was complete by 7 days; most of these patients completely healed in 5 days. All patients who did not receive tretinoin healed by 11 days, but none healed sooner than 7 days. No milia or postinflammatory hyperpigmentation was experienced by patients treated with tretinoin when the drug was resumed within 1 week after dermabrasion. In the group that received no tretinoin, milia and postinflammatory hyperpigmentation occurred in 28% of patients postoperatively.
D000152:Acne Vulgaris / Q000628:therapy*; D000287:Administration, Topical; D003869:Dermabrasion; D006801:Humans; D011182:Postoperative Care; D011300:Preoperative Care; D014212:Tretinoin / Q000008:administration & dosage / Q000627:therapeutic use*; D014945:Wound Healing / Q000187:drug effects
D014212:Tretinoin