title: [Vascular-platelet link in the hemostatic system of diabetics].
abstract: Activation of the vascular-platelet link of the hemostasis system: an increase in platelet ADP-induced aggregation, the appearance of platelet aggregates in the vascular bed, an increase in the patients' plasma of beta-thromboglobulin concentration, thrombocytic factor 4, a decrease in antiaggregation activity of the vascular wall and sensitifity of patients' platelets to antiaggregation action of acetylsalicylic acid, was found in diabetes mellitus patients. In the authors' opinion, the above changes play a role in disorders of the microcirculation of the organs and tissues and development of complications in these patients.
mesh_terms: D000244:Adenosine Diphosphate; D000328:Adult; D000936:Antigen-Antibody Complex / Q000032:analysis; D001241:Aspirin; D001792:Blood Platelets / Q000502:physiology*; D001808:Blood Vessels / Q000503:physiopathology*; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology*; D003925:Diabetic Angiopathies / Q000209:etiology; D005260:Female; D006487:Hemostasis; D006801:Humans; D008297:Male; D010974:Platelet Aggregation; D010978:Platelet Factor 4 / Q000032:analysis; D001620:beta-Thromboglobulin / Q000032:analysis
chemical_list: D000936:Antigen-Antibody Complex; D001620:beta-Thromboglobulin; D010978:Platelet Factor 4; D000244:Adenosine Diphosphate; D001241:Aspirin
vernacular_title: Sosudisto-trombotsitarnoe zveno sistemy gemostaza bol'nykh sakharnym diabetom.