[Effect of exogenous interleukin 2 on the functional activity of immunocompetent cells in mice with transplanted tumors].
The use of two independent test-systems (intravenous adoptive transfer of immune response on tumour cells by intact syngenic recipient and mixed cultivation of immunocompetent and tumour cells in diffusion chambers) made it possible to establish that exogenous IL-2 possesses an expressive capacity both to the positive and to the negative modulation of immunological mechanisms during the tumour growth.
D000818:Animals; D002478:Cells, Cultured; D005260:Female; D007111:Immunity, Cellular / Q000187:drug effects; D007114:Immunization; D007376:Interleukin-2 / Q000276:immunology*; D008198:Lymph Nodes / Q000276:immunology; D008748:Methylcholanthrene; D051379:Mice; D008807:Mice, Inbred BALB C; D009368:Neoplasm Transplantation; D051381:Rats; D012208:Rhabdomyosarcoma / Q000139:chemically induced / Q000276:immunology*; D013154:Spleen / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000187:drug effects* / Q000276:immunology; D013997:Time Factors
D007376:Interleukin-2; D008748:Methylcholanthrene
Vliianie ékzogennogo interleĭkina-2 na funktsional'nuiu aktivnost' immunokompetentnykh kletok mysheĭ s perevivnymi opukholiami.