title: [Detection of immunoglobulin deposits in paraffin embedded skin with the peroxidase-antiperoxidase (PAP) method].
abstract: The peroxidase-antiperoxidase (PAP) technique allows the detection of immunoglobulin deposits in formalin-fixed, paraffin-embedded tissue. The PAP technique may be used as an alternative to the direct immunofluorescence method on frozen, unfixed skin. In addition, the PAP technique is suitable for retrospective evaluation of histological samples.
mesh_terms: D005455:Fluorescent Antibody Technique; D006801:Humans; D007105:Immune Complex Diseases / Q000473:pathology; D007124:Immunoenzyme Techniques; D007136:Immunoglobulins / Q000378:metabolism*; D008179:Lupus Erythematosus, Discoid / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000473:pathology; D010391:Pemphigoid, Bullous / Q000473:pathology; D010392:Pemphigus / Q000473:pathology; D012867:Skin / Q000473:pathology*; D012871:Skin Diseases / Q000473:pathology*; D014657:Vasculitis / Q000473:pathology
chemical_list: D007136:Immunoglobulins
vernacular_title: Nachweis von Immunglobulinablagerungen in paraffineingebetteter Haut mit der Peroxidase-Antiperoxidase (PAP)-Methode.