title: Adverse behavioral effects of amantadine therapy in Huntington's disease.
abstract: Two patients with advanced Huntington's disease manifested a marked increase in irritability and aggressiveness when treated with amantadine during an epidemic of influenza. Amantadine should be used with caution in patients with Huntington's disease.
mesh_terms: D000328:Adult; D000374:Aggression / Q000187:drug effects*; D000547:Amantadine / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D006816:Huntington Disease / Q000523:psychology*; D007251:Influenza, Human / Q000517:prevention & control; D008297:Male
chemical_list: D000547:Amantadine