Potentiating effect of aldosterone on the diuretic action of atrial extract.
The typical stimulatory effect of a rat heart atrial extract on urinary water, sodium, potassium and kallikrein excretion is significantly increased by a previous administration of aldosterone (0.5 microgram/100 g b. wt) in the rat.
D000450:Aldosterone / Q000494:pharmacology*; D000818:Animals; D009320:Atrial Natriuretic Factor / Q000494:pharmacology*; D004231:Diuresis / Q000187:drug effects*; D004357:Drug Synergism; D005260:Female; D007610:Kallikreins / Q000652:urine; D007668:Kidney / Q000187:drug effects / Q000502:physiology*; D009318:Natriuresis / Q000187:drug effects; D011188:Potassium / Q000652:urine; D051381:Rats; D011919:Rats, Inbred Strains
D000450:Aldosterone; D009320:Atrial Natriuretic Factor; D007610:Kallikreins; D011188:Potassium