Immune response to hepatitis B vaccine in hemodialysis patients.
The impaired immune reactivity of hemodialysis patients has been reported to interfere with adequate antibody responses to standard doses of hepatitis B vaccine. In 22 hemodialysis patients, however, a 92% conversion rate could be obtained by administering multiple doses of plasma-derived MSD-vaccine. As the cost of such an amplified vaccination schedule is still lower than the cost of one dialysis treatment, this active vaccination policy for highly susceptible patients appears financially justified.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000917:Antibody Formation; D004334:Drug Administration Schedule; D005260:Female; D017325:Hepatitis B Vaccines; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D014761:Viral Hepatitis Vaccines / Q000008:administration & dosage / Q000276:immunology*
D017325:Hepatitis B Vaccines; D014761:Viral Hepatitis Vaccines