Effect of tumour regression on serum and tissue copper concentration in mice bearing induced fibrosarcoma.
Serum and tissue copper concentration was determined in mice bearing induced fibrosarcoma after successful chemotherapeutic treatment. The results showed a significant depression in copper concentration in the serum and tumour tissue after treatment with anti-cancer drugs. However, the liver copper concentration showed no significant change in treated groups of mice compared to before treatment.
D000818:Animals; D003300:Copper / Q000097:blood / Q000378:metabolism*; D005354:Fibrosarcoma / Q000188:drug therapy* / Q000378:metabolism; D005472:Fluorouracil / Q000627:therapeutic use*; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D051379:Mice; D008805:Mice, Inbred A; D016685:Mitomycin; D008937:Mitomycins / Q000627:therapeutic use*
D008937:Mitomycins; D016685:Mitomycin; D003300:Copper; D005472:Fluorouracil