Comparative results of percutaneous transluminal coronary angioplasty in patients with dynamic versus fixed coronary stenosis.
This study compares the results of percutaneous transluminal coronary angioplasty in a group of 132 patients (group A) with fixed atherosclerotic narrowing (no spontaneous or ergonovine-provoked spasm) and in a group of 97 patients (group B) with dynamic coronary stenosis (spasm superimposed on the stenosis). All these patients underwent complete follow-up angiography. The rate of restenosis (defined as a loss of 50% of the initial gain) was significantly higher in patients in group B (dynamic coronary stenosis) than in group A (fixed narrowing) (35 versus 22%, p less than 0.05). Despite treatment with a calcium antagonist, coronary artery spasm persisted in 44% of the patients in group B and was detected for the first time in 15% of the patients in group A. Thus, in patients with dynamic coronary stenosis, the results of coronary angioplasty were less satisfactory than in patients with fixed narrowing, and in both groups coronary artery spasm was frequently (64%) superimposed on the restenosis.
D000328:Adult; D000368:Aged; D000788:Angina Pectoris, Variant / Q000628:therapy; D000800:Angioplasty, Balloon / Q000009:adverse effects; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D017023:Coronary Angiography; D003327:Coronary Disease / Q000628:therapy*; D004874:Ergonovine; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence
D002121:Calcium Channel Blockers; D004874:Ergonovine