Effect of chymotryptic troponin T subfragments on the calcium ion-sensitivity of ATPase and superprecipitation of actomyosin.
One of the chymotryptic troponin T subfragments, troponin T2, reconstituted approximately 80% of the Ca2+-sensitizing action of troponin T on actomyosin in the presence of troponin C, troponin I, and tropomyosin. This indicates that the Ca2+-regulatory property of troponin T is mostly localized in the troponin T2 region of the C-terminal 101 residues.
D000205:Actomyosin / Q000378:metabolism*; D000818:Animals; D000252:Calcium-Transporting ATPases / Q000378:metabolism*; D002918:Chymotrypsin / Q000378:metabolism*; D009132:Muscles / Q000201:enzymology; D010446:Peptide Fragments / Q000378:metabolism; D011817:Rabbits; D014335:Tropomyosin / Q000378:metabolism; D014336:Troponin / Q000378:metabolism*; D019209:Troponin C; D019210:Troponin I; D020107:Troponin T
D010446:Peptide Fragments; D014335:Tropomyosin; D014336:Troponin; D019209:Troponin C; D019210:Troponin I; D020107:Troponin T; D000205:Actomyosin; D002918:Chymotrypsin; D000252:Calcium-Transporting ATPases