[Comparative characteristics of adenosine triphosphatase activity in the erythrocytes of patients with acute and chronic liver diseases, chronic cholecystitis and in HBs antigen carriers].
A decrease in sodium, potassium and anion (HCO3)-activated erythrocyte ATPases is noted in patients with acute viral hepatitides A and B, chronic persisting hepatitis, liver cirrhosis, chronic cholecystitis and in HBs-antigen carriers, the reduction of HCO8-ATPase being more noticeable. A degree of expression of the above changes depends on the severity of a pathological process in the liver. The most serious changes are noted in liver cirrhosis. In this disease calcium ATPase activity is also on a decrease. Erythrocyte ATPase activity is lowered in chronic cholecystitis to a lesser degree. In patients with chronic persisting hepatitis and liver cirrhosis erythrocyte ATPase activity slightly increases, however it remains significantly lowered as compared to the control level. The determination of erythrocyte ATPase activity can be used for assessment of the status of patients with acute and chronic liver diseases.
D000251:Adenosine Triphosphatases / Q000097:blood*; D000293:Adolescent; D000328:Adult; D000368:Aged; D002353:Carrier State / Q000175:diagnosis; D002648:Child; D002764:Cholecystitis / Q000175:diagnosis*; D004796:Clinical Enzyme Tests; D004912:Erythrocytes / Q000201:enzymology*; D006509:Hepatitis B / Q000175:diagnosis; D006514:Hepatitis B Surface Antigens; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis*; D008875:Middle Aged
D006514:Hepatitis B Surface Antigens; D000251:Adenosine Triphosphatases
Sravnitel'naia kharakteristika aktivnosti adenozintrifosfataz éritrotsitov u bol'nykh ostrymi i khronicheskimi zabolevaniiami pecheni, khronicheskim kholetsistitom i nositeleĭ HBs-antigena.