Human autoimmune serum antibodies against gag gene p30 retroviral protein also react with a U1-SnRNP 68K comigrant protein.
Using Immunoblotting procedure, we showed that autoimmune human antibodies reacting with mouse retrovirus gag-p30 also reacted with a HnRNP 68 Kd protein. Since U1-SnRNP 68 K and p30-gag proteins show 40% homology, the detected 68 Kd protein is likely to be the U1-RNA 68 K.
D000936:Antigen-Antibody Complex / Q000032:analysis; D001323:Autoantibodies / Q000276:immunology*; D015683:Gene Products, gag; D006367:HeLa Cells / Q000166:cytology; D006801:Humans; D008970:Molecular Weight; D008979:Moloney murine leukemia virus / Q000235:genetics*; D012191:Retroviridae Proteins / Q000276:immunology*; D012261:Ribonucleoproteins / Q000276:immunology*; D017411:Ribonucleoproteins, Small Nuclear
D000936:Antigen-Antibody Complex; D001323:Autoantibodies; D015683:Gene Products, gag; D012191:Retroviridae Proteins; D012261:Ribonucleoproteins; D017411:Ribonucleoproteins, Small Nuclear