title: Impact of topical metronidazole on the skin and colon microflora in patients with rosacea.
abstract: 20 patients with rosacea were treated with a 1% metronidazole cream b.i.d. for one month. Sixteen out of twenty patients improved. The skin and intestinal microflora were studied before, during and after treatment. Topical metronidazole did not cause any significant changes in the microflora. No side effects were observed.
mesh_terms: D000287:Administration, Topical; D001419:Bacteria / Q000187:drug effects*; D001431:Bacteriological Techniques; D003106:Colon / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use*; D008875:Middle Aged; D012393:Rosacea / Q000188:drug therapy*; D012867:Skin / Q000382:microbiology*
chemical_list: D008795:Metronidazole