[Cerebral metabolic data in positron emission tomography in physiologic aging. Review of the literature].
Following a summary of the general principles and limitations of metabolic measurements by positron emission tomography and of the different indices used to interpret the data, the authors review the results of published studies on physiological aging. Globally, with strict inclusion criteria absolute metabolic values at rest and under partial sensorial deprivation are little or not modified by age. In contrast, functional interactions between regions, as deduced from metabolic intercorrelations, are perhaps different in elderly people. In any case, positron emission tomography seems to discriminate between normal aging and different patterns of pathological aging. Technical improvements, more refined neuropsychological correlations and the use of dynamic activation paradigms will no doubt provide, in the future, a better definition of normal and pathological aging at positron tomography.
D000375:Aging / Q000378:metabolism*; D001921:Brain / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D010100:Oxygen / Q000378:metabolism*; D014055:Tomography, Emission-Computed
D005947:Glucose; D010100:Oxygen
Données métaboliques cérébrales en tomographie d'émission par positons au cours du vieillissement physiologique. Revue de la littérature.