Kallikrein produces a new peptide that specifically stimulates prostacyclin formation in vascular endothelial cells by activating phospholipase A2.
D000818:Animals; D002478:Cells, Cultured; D004727:Endothelium / Q000187:drug effects / Q000378:metabolism; D004789:Enzyme Activation / Q000187:drug effects; D011464:Epoprostenol / Q000096:biosynthesis*; D007610:Kallikreins / Q000494:pharmacology*; D010741:Phospholipases A / Q000378:metabolism; D054467:Phospholipases A2
D011464:Epoprostenol; D010741:Phospholipases A; D054467:Phospholipases A2; D007610:Kallikreins