[Production of allotype by bone marrow cells transferred to rabbits subjected to suppressor treatment by allotype].
Inbred rabbits of B/J strain were immunized against Salmonella typhi and their bone marrow cells plus LPS were injected into (Chbb: HM X B/J) F1 hybrids at the age of 3-7 weeks, which had received at birth a treatment of the allotype suppression. Antityphoid antibodies bearing the suppressed allotype were found in the serum of the recipients, which showed no signs of the graft versus host reaction.
D000818:Animals; D000831:Animals, Newborn; D000917:Antibody Formation; D001853:Bone Marrow / Q000276:immunology; D016026:Bone Marrow Transplantation; D007126:Immunoglobulin Allotypes / Q000096:biosynthesis* / Q000276:immunology; D007165:Immunosuppression Therapy; D008070:Lipopolysaccharides / Q000276:immunology; D011817:Rabbits; D012485:Salmonella typhi / Q000276:immunology
D007126:Immunoglobulin Allotypes; D008070:Lipopolysaccharides
Production de l'allotype par des cellules de moelle osseuse transférées chez des lapins soumis à un traitement suppresseur de l'allotype.