Tubulointerstitial immune complex nephritis in a patient with cutaneous vasculitis.
We report a patient who suffered from cutaneous vasculitis with renal involvement comprising tubulointerstitial (TI) nephritis and relatively mild glomerulitis. Renal biopsy revealed immune deposits both in mesangium and along tubular basement membrane (TBM), suggesting that immune complexes played a significant role in the development of renal damage. Although it is well known that vasculitic syndromes commonly affect glomeruli, this report is the first to demonstrate tubulointerstitial immune complex nephritis in a patient with cutaneous vasculitis.
D000328:Adult; D001706:Biopsy; D005260:Female; D006801:Humans; D007105:Immune Complex Diseases / Q000209:etiology* / Q000473:pathology; D009395:Nephritis, Interstitial / Q000209:etiology* / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
D011239:Prednisolone