Novel arylthio- and arylsulfonylpropyloxyacetophenones: design and synthesis of L-648,051 and L-649,923, potent antagonists of leukotriene D4.
D000818:Animals; D001980:Bronchi / Q000187:drug effects; D006168:Guinea Pigs; D007651:Keto Acids; D010654:Phenylbutyrates / Q000138:chemical synthesis / Q000494:pharmacology*; D013189:SRS-A / Q000037:antagonists & inhibitors*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013450:Sulfones
D007651:Keto Acids; D010654:Phenylbutyrates; D013189:SRS-A; D013450:Sulfones; C052024:L 648051; C050033:L 649923