title: [Medico-genetic study of the Uzbekistan population. X. Hereditary forms of hearing impairment in the Khorezm and Samarkand regions].
abstract: Medical-genetic study in some populations of Khorezm (about 200,000) and Samarkand (about 56,000) provinces was performed with the view of identification of all family cases of deafness and deaf-mutism. 53 families with 140 affected patients were registered, in total. 8 nozological forms were found in this study, the most frequent being autosomal-recessive ones (6 nozological forms, 48 families, 122 patients). The autosomal-dominant forms were represented by 2 nozological forms (5 families with 18 patients). The reason for predominance of autosomal-recessive deafness in Uzbek population is discussed.
mesh_terms: D005799:Genes, Dominant; D005808:Genes, Recessive; D005828:Genetics, Population; D006311:Hearing Disorders / Q000453:epidemiology / Q000235:genetics*; D006801:Humans; D014610:Uzbekistan
vernacular_title: Mediko-geneticheskoe izuchenie naseleniia Uzbekistana. Soobshchenie X. Nasledstvennye formy narusheniĭ slukha v Khorezmskoĭ i Samarkandskoĭ oblastiakh.