title: Concomitant bronchodilator therapy and ipratropium bromide. A clinical review.
abstract: This article reviews the use of ipratropium bromide concomitantly with other bronchodilators, with a focus on its use in patients with asthma. Patients with asthma generally have demonstrated a greater response to the combination of ipratropium and other anti-asthma drugs than to either drug alone. No increase in side effects has been observed when ipratropium has been used in combination with other bronchodilating drugs. Overall, the combination of ipratropium with other agents appears to offer promise in therapy for asthma; further investigation of combinations in larger patient populations is warranted.
mesh_terms: D001249:Asthma / Q000188:drug therapy / Q000503:physiopathology; D001286:Atropine Derivatives / Q000627:therapeutic use*; D001993:Bronchodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005541:Forced Expiratory Volume; D006801:Humans; D009241:Ipratropium / Q000008:administration & dosage / Q000627:therapeutic use*; D008173:Lung Diseases, Obstructive / Q000188:drug therapy / Q000503:physiopathology; D013997:Time Factors
chemical_list: D001286:Atropine Derivatives; D001993:Bronchodilator Agents; D009241:Ipratropium