[Nyctohemeral blood pressure profiling by automatic measurement in ambulatory hypertensive patients. Treatment with acebutolol].
Variations in night and day blood pressure were evaluated in 11 patients with essential hypertension. The instrument used (Pressurometer II) automatically records blood pressure every 15 minutes for a mean period of 22 hours and ECG tracings continuously. The mean values of arterial pressure and heart rate were significantly higher during day time than at night, revealing a relative "hypotension" and "bradycardia" during sleep. The cardioselective beta-blocker acebutolol induced a significant fall in diurnal and nocturnal blood pressure, thus uniformly lowering the 24-hour profile.
D000070:Acebutolol / Q000627:therapeutic use*; D000328:Adult; D000553:Ambulatory Care; D001795:Blood Pressure Determination / Q000379:methods*; D002940:Circadian Rhythm; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods; D013997:Time Factors
D000070:Acebutolol
Profil tensionnel nycthéméral par mesure automatique chez des hypertendus ambulatoires. Traitement par l'acébutolol.