Event-free survival following nonemergency myocardial revascularization during hypothermic fibrillatory arrest.
To better assess the late results of hypothermic fibrillatory arrest during myocardial revascularization, 1,000 consecutive patients having nonemergency coronary artery grafting during hypothermic fibrillatory arrest from August, 1979, through November, 1984, were studied to determine event-free survival. Hospital mortality was 0.4% and the rate of perioperative myocardial infarction, 1.8%. At follow-up (mean, 30.5 months), 11 patients had sustained an interval nonfatal myocardial infarction, 3 had had percutaneous angioplasty, and 2 had undergone reoperative revascularization. Actuarial survival at five years was 91.6 +/- 2.0%. Actuarial event-free rates at five years were 97.7 +/- 0.8% for myocardial infarction, 99.4 +/- 0.4% for percutaneous transluminal coronary angioplasty, 99.5 +/- 0.4% for reoperative revascularization, and 88.6 +/- 2.2% for all combined morbidity and mortality. Among the 122 patients meeting randomizable admission criteria of the Coronary Artery Surgery Study, there were no operative deaths and no perioperative infarctions, and the actuarial survival was 97.5% at five years. Hypothermic fibrillatory arrest is effective for myocardial preservation during coronary revascularization and when combined with complete revascularization, yields excellent event-free survival.
D000206:Actuarial Analysis; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000800:Angioplasty, Balloon; D003327:Coronary Disease / Q000150:complications / Q000401:mortality / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006324:Heart Arrest, Induced / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D007036:Hypothermia, Induced; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000401:mortality / Q000601:surgery; D009204:Myocardial Revascularization / Q000009:adverse effects* / Q000401:mortality; D011183:Postoperative Complications / Q000453:epidemiology* / Q000628:therapy; D012086:Reoperation; D012189:Retrospective Studies