[A case of recurrence of gastric cancer with an abdominal wall tumor responding to intratumoral OK-432 administration].
Intratumoral administration of 5 K.E. OK-423 was given every other day for a patient with an abdominal wall recurrence of gastric cancer. After a total dose of 465 K.E. the abdominal tumor turned necrotic and its demarcation was monitored. Finally, the tumor separated and fell from the abdominal wall. Histologically, marked infiltration of neutrophils, lymphocytes, and macrophages were observed in the cancerous tissue. Clinically, local pain lessened and the serum CEA level decreased. PPD and PHA skin tests were markedly stimulated. A long term small-dose intratumoral administration of OK-432 seemed to be effective for a local recurrence of gastric cancer.
D000009:Abdominal Muscles; D000230:Adenocarcinoma / Q000556:secondary* / Q000628:therapy; D000328:Adult; D001688:Biological Products / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D010844:Picibanil / Q000008:administration & dosage* / Q000627:therapeutic use; D012983:Soft Tissue Neoplasms / Q000556:secondary* / Q000628:therapy; D013274:Stomach Neoplasms
D001688:Biological Products; D010844:Picibanil