Bisphosphonates can reduce osteoclastic bone resorption by two different mechanisms.
D000818:Animals; D001862:Bone Resorption / Q000187:drug effects*; D001842:Bone and Bones / Q000196:embryology; D002454:Cell Differentiation; D002633:Chemotaxis; D004002:Clodronic Acid / Q000494:pharmacology; D046508:Culture Techniques; D004164:Diphosphonates / Q000494:pharmacology*; D012968:Etidronic Acid / Q000494:pharmacology; D005260:Female; D008099:Liver / Q000196:embryology; D008663:Metacarpus; D051379:Mice; D010010:Osteoclasts / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D000077268:Pamidronate; D011247:Pregnancy; D011884:Radius
D004164:Diphosphonates; D004002:Clodronic Acid; D012968:Etidronic Acid; D000077268:Pamidronate