title: [The effect of celiprolol on driving ability. An experimental psychological and comparative clinical study].
abstract: In this open study 21 hypertensive patients (WHO I + II) received after a one-week placebo period a 4-week treatment with a once daily dose of 300 mg celiprolol hydrochloride (Selectol). 21 normotensive subjects receiving placebo during the whole trial period and 20 normotensives receiving no treatment at all served as comparative groups. Prior to the treatment the hypertensive subjects showed a marked lack in acquisition and reproduction of complex visual information and their subjective emotional condition was more negative than that of the healthy subjects. A one-week placebo treatment had no influence on the parameters under test. One single dose of celiprolol had no influence on the specific capacity of driving a motor vehicle and on the emotional condition. Long-term medication of celiprolol did not impair the driving ability. The subjective emotional condition improved as desired.
mesh_terms: D000328:Adult; D001334:Automobile Driving; D017272:Celiprolol; D004644:Emotions / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D008297:Male; D011412:Propanolamines / Q000009:adverse effects* / Q000627:therapeutic use; D011597:Psychomotor Performance / Q000187:drug effects; D013997:Time Factors
chemical_list: D011412:Propanolamines; D017272:Celiprolol
vernacular_title: Einfluss von Celiprolol auf die Fahrtüchtigkeit. Eine experimental-psychologische und klinische Vergleichsuntersuchung.