[Excretion of 2,3-dihydroxybenzoic acid by an enterobactin-negative multiresistant wild strain of Salmonella typhimurium].
In investigations of iron siderophores produced by different Salmonella typhimurium strains we found a strain deficient in enterobactin production. Using microbiological and chemical methods, we detected the production and excretion of 2,3-dihydrobenzoic acid, a metabolite of the enterobactin biosynthesis pathway. The strain was able to produce aerobactin. We suggest that the iron uptake of pathogenic strains can be mediated by aerobactin alone. For a correct enterobactin bioassay it is necessary to use a mutant unable to grow on 2,3-dihydroxybenzoic acid.
D002854:Chromatography, Paper; D004758:Enterobactin / Q000096:biosynthesis*; D006877:Hydroxamic Acids / Q000096:biosynthesis; D062385:Hydroxybenzoates / Q000378:metabolism*; D007501:Iron / Q000378:metabolism; D009154:Mutation; D012486:Salmonella typhimurium / Q000235:genetics / Q000378:metabolism*; D012694:Serine / Q000031:analogs & derivatives*
D006877:Hydroxamic Acids; D062385:Hydroxybenzoates; C031819:aerobactin; D004758:Enterobactin; D012694:Serine; C009135:2,3-dihydroxybenzoic acid; D007501:Iron
DHBA (2,3-Dihydroxybenzoesäure)-Ausscheidung durch einen enterobactinnegativen multiresistenten Salmonella typhimurium-Wildstamm.