Z-transformed EEG power spectra of children with Down syndrome vs a control group.
Standardized EEG records of eighty-eight children with Down syndrome aged between six months and five years were analysed. The EEGs were digitalized, evaluated by spectral analysis, and subjected to z-transformation, a method which allows a direct comparison of the Down syndrome children with a normal control group (Munich Developmental Longitudinal Study). The results show a significant increase in absolute power, especially theta power; the absolute alpha power is less markedly increased or even decreased. The most significant differences, however, are observed when calculating the relative alpha power. Children with Down syndrome show a reduced relative alpha power already at the age of six months, and this reduction becomes even more prominent with growing age.
D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000175:diagnosis* / Q000503:physiopathology; D004569:Electroencephalography; D005071:Evoked Potentials; D005625:Frontal Lobe / Q000503:physiopathology; D006801:Humans; D007223:Infant; D009778:Occipital Lobe / Q000503:physiopathology; D010296:Parietal Lobe / Q000503:physiopathology