title: [Histochemical study of the mucus in villous tumors of the colon].
abstract: The study deals with a comparative histochemical evaluation of mucus secreted by normal large bowel mucosa and that obtained from 10 villous tumors (colorectal adenoma--6 and colorectal adenocarcinoma--4). Level of production and chemical composition of mucus changed with tumor advancement: an increase in neutral mucopolysaccharides synthesis was matched by lowered production of acid ones. Also, deranged sulphatation of mucus and changes in sialomucin profile were established.
mesh_terms: D000230:Adenocarcinoma / Q000378:metabolism / Q000473:pathology*; D000236:Adenoma / Q000378:metabolism / Q000473:pathology*; D000368:Aged; D003110:Colonic Neoplasms / Q000378:metabolism / Q000473:pathology*; D006025:Glycosaminoglycans / Q000032:analysis; D006651:Histocytochemistry; D006801:Humans; D007413:Intestinal Mucosa / Q000032:analysis; D008875:Middle Aged; D009093:Mucus / Q000032:analysis* / Q000378:metabolism
chemical_list: D006025:Glycosaminoglycans
vernacular_title: Gistokhimicheskoe issledovanie sostava slizi vorsinchatykh opukholeĭ tolstoĭ kishki.