Skin pathology in industrial workers exposed to synthetic corticosteroids.
Systemic and cutaneous side effects observed in some workers of a company producing synthetic corticosteroids are described. The production process and the results of clinical and laboratory investigations are shown. A high incidence of skin and internal disorders (erythema, telangiectasia, acne, purpuric lesions and inhibition of the pituitary-adrenal axis) were found.
D000152:Acne Vulgaris / Q000139:chemically induced; D003345:Corticosterone / Q000009:adverse effects*; D009783:Dermatitis, Occupational / Q000139:chemically induced* / Q000473:pathology; D003875:Drug Eruptions / Q000473:pathology*; D004438:Ecchymosis / Q000139:chemically induced; D004890:Erythema / Q000139:chemically induced; D005260:Female; D006801:Humans; D008297:Male; D012867:Skin / Q000473:pathology
D003345:Corticosterone