[Characteristics of lipid composition, lipid peroxidation intensity and ATPase activity of lymphocytes in children with acute respiratory viral infections].
Content of total lipids, intensity of lipid peroxidation and activity of ATPases were studied in lymphocytes of children with acute respiratory-viral infection (ARVI). Decrease in the content of total lipids correlated with lipid peroxidation in ARVI. At the same time, a decrease in the activity of ATPases occurred due to a decrease in the content of total lipids and alteration in the phospholipid composition of lymphocyte membranes. At the period of convalescence the patterns studied tended to normalization only in children with non-complicated forms of ARVI. Active and slowly-developed lipid peroxidation in lymphocytes of various children groups suggest dissimilar alterations in the structure and composition of the cellular membranes, which increases our knowledge on pathogenesis of ARVI.
D000208:Acute Disease; D000251:Adenosine Triphosphatases / Q000097:blood*; D002675:Child, Preschool; D006801:Humans; D008054:Lipid Peroxides / Q000097:blood*; D008055:Lipids / Q000097:blood*; D008214:Lymphocytes / Q000201:enzymology*; D010743:Phospholipids / Q000097:blood; D012141:Respiratory Tract Infections / Q000201:enzymology / Q000378:metabolism*; D014777:Virus Diseases / Q000201:enzymology / Q000378:metabolism*
D008054:Lipid Peroxides; D008055:Lipids; D010743:Phospholipids; D000251:Adenosine Triphosphatases
Kharakteristika lipidnogo sostava, intensivnosti perekisnogo okisleniia lipidov i ATFaznoĭ aktivnosti limfotsitov deteĭ pri ostrykh respiratorno-virusnykh infektsiiakh.