[Indications and results of transcatheter fibrinolysis in acute arterial occlusions].
The authors' experience is reported on intravascular fibrinolytic therapy with urokinase in acute arterial obstructions. Thirty-eight patients were treated, from 1983 to 1986, for acute thrombosis and/or thromboembolization, 22 of which developed on an atherosclerotic lesion, and 10 on a surgical stenotic by-pass graft. A complete vascular recanalization has been obtained, at the end of the procedure, in 69.4% of the cases, 77.7% had a definite final clinical improvement. The results correspond to the medium statistical level of the various casuistics analyzed for comparison. Surgery has been performed on 27.7% of the patients. Complications have been observed in 8% of the cases. IAF technique is of greatest value in the treatment of those lesions; better results have been obtained with intra-thrombus injection of the drug (as emphasized by many authors) in association with PTA and surgery. A close cooperation between interventional radiology, vascular surgery and angiology is therefore necessary in this field.
D000208:Acute Disease; D000792:Angiography; D000800:Angioplasty, Balloon; D001012:Aorta, Abdominal; D001018:Aortic Diseases / Q000188:drug therapy; D001027:Aortography; D001157:Arterial Occlusive Diseases / Q000188:drug therapy* / Q000601:surgery / Q000628:therapy; D001807:Blood Vessel Prosthesis; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006801:Humans; D011655:Pulmonary Embolism / Q000188:drug therapy; D013927:Thrombosis / Q000188:drug therapy; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage
D005343:Fibrinolytic Agents; D014568:Urokinase-Type Plasminogen Activator
Indicazioni e risultati della fibrinolisi trans-catetere nelle occlusioni arteriose acute.