Isometric relaxation of hypertrophied right ventricle in rats.
In rats with experimental hypertrophy of the right ventricle due to chronic increase in pressure load -dP/dTmax, a parameter of isometric relaxation, is significantly reduced at a stage of impairment of myocardial function at which the parameter of isometric contractility still remains unaffected.
D000818:Animals; D002306:Cardiac Volume; D006332:Cardiomegaly / Q000503:physiopathology*; D005260:Female; D006352:Heart Ventricles / Q000503:physiopathology*; D006976:Hypertension, Pulmonary / Q000503:physiopathology; D000860:Hypoxia / Q000503:physiopathology; D009119:Muscle Contraction; D051381:Rats; D011919:Rats, Inbred Strains