title: Death of Mycobacterium lepraemurium after multiplication in CBA, BALB/c and nude mice.
abstract: The unexpected death of Mycobacterium lepraemurium in the course of systemic infection of mice, previously noted in the spleens of CBA mice, has been demonstrated in the spleens of BALB/c nu/+ and BALB/c nu/nu mice and also in the livers and other organs of mice of all three strains. That the same phenomenon was observed in nu/nu mice indicates that the mechanism of bacterial death does not involve a T-lymphocyte-mediated cellular immune response on the part of the mice.
mesh_terms: D000818:Animals; D007111:Immunity, Cellular; D051379:Mice; D008807:Mice, Inbred BALB C; D008808:Mice, Inbred CBA; D008819:Mice, Nude; D009164:Mycobacterium Infections / Q000276:immunology / Q000382:microbiology*; D009167:Mycobacterium lepraemurium / Q000254:growth & development*; D013047:Specific Pathogen-Free Organisms; D013154:Spleen / Q000382:microbiology*; D013601:T-Lymphocytes / Q000276:immunology