[Fibrinolytic activity of the blood and synovial fluid in patients with rheumatoid arthritis].
A study of the blood fibrinolytic activity (BFA) in 95 patients with rheumatoid arthritis (RA) and in their 120 relatives and of the fibrinolytic activity of the synovial fluid (FASF) in 26 RA patients showed BFA and FASF suppression in most of them. A high activity of the contact factors and high concentrations of fibrinogen degradation products were revealed in the synovial fluid. BFA and RASF changes can contribute to the progression of rheumatoid synovitis.
D000293:Adolescent; D000328:Adult; D001172:Arthritis, Rheumatoid / Q000097:blood*; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D005340:Fibrinogen / Q000032:analysis; D005341:Fibrinolysin / Q000032:analysis; D005342:Fibrinolysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D010958:Plasminogen / Q000032:analysis; D013582:Synovial Fluid / Q000502:physiology*
D005338:Fibrin Fibrinogen Degradation Products; D005340:Fibrinogen; D010958:Plasminogen; D005341:Fibrinolysin
Fibrinolitichaskaia aktivnost' krovi i sinovial'noĭ zhidkosti u bol'nykh revmatoidnym artritom.