Indomethacin increases the cytotoxicity of methotrexate in vitro and in vivo.
D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D004357:Drug Synergism; D004848:Epithelium / Q000187:drug effects; D006801:Humans; D066298:In Vitro Techniques; D007213:Indomethacin / Q000494:pharmacology*; D007422:Intestines / Q000187:drug effects; D008727:Methotrexate / Q000494:pharmacology*; D051379:Mice; D009374:Neoplasms, Experimental / Q000188:drug therapy*
D007213:Indomethacin; D008727:Methotrexate