Testing of cosmetics and toiletries.
Cosmetics and toiletries are indispensable everyday products used by the vast majority of the population. Evaluation of safety is needed to reduce the risk of side effects from intentional and unintentional use. This paper describes factors involved in the choice of test strategy for determining the dermatotoxicological profile of the products. Emphasis is placed on tests for skin irritation, contact allergy, acne and subjective symptoms elicited by the products.
D000152:Acne Vulgaris / Q000139:chemically induced; D000827:Animal Welfare; D000818:Animals; D003358:Cosmetics / Q000009:adverse effects / Q000633:toxicity*; D003877:Dermatitis, Contact / Q000209:etiology; D004353:Drug Evaluation, Preclinical / Q000379:methods; D006801:Humans; D012867:Skin / Q000187:drug effects*
D003358:Cosmetics