Onychomycosis in graft versus host disease.
Graft versus host disease is associated with a myriad of cutaneous signs and few nail manifestations. A case of documented chronic graft versus host disease with the initial cutaneous presentation of white superficial onychomycosis is presented. The patient developed a lichenoid eruption in an unusual distribution and a reticulated hyperpigmentation of the face. Culture of the nails was positive for Trichophyton rubrum, an uncommon cause of white superficial onychomycosis, this being the third known reported case. Histopathologic examination revealed fungal elements in the superficial nail plate with an absence of fungus in the ventral aspect of the nail plate. A summary of cutaneous skin and nail manifestations in graft versus host disease is presented.
D000328:Adult; D006086:Graft vs Host Disease / Q000150:complications*; D006801:Humans; D008297:Male; D009059:Mouth Diseases / Q000209:etiology; D009260:Nail Diseases / Q000209:etiology; D014009:Onychomycosis / Q000209:etiology*