[Possible inducible nature of radioresistant DNA synthesis stimulated by 5-fluorodeoxyuridine].
A study was made of the effect of cycloheximide on the radioresistant DNA synthesis stimulated by preincubation of cells with 5-fluorodeoxyuridine (FdUrd). It was shown that after the cycloheximide treatment the radioresistant DNA synthesis was absent while in FdUrd-treated cells it did occur. It is assumed that the FdUrd-stimulated radioresistant DNA synthesis is of an inducible nature.
D002110:Caffeine / Q000494:pharmacology; D003513:Cycloheximide / Q000494:pharmacology; D004247:DNA / Q000096:biosynthesis* / Q000528:radiation effects; D004260:DNA Repair / Q000187:drug effects / Q000528:radiation effects*; D005467:Floxuridine / Q000494:pharmacology*; D005720:Gamma Rays; D006367:HeLa Cells; D006801:Humans; D011836:Radiation Tolerance
D005467:Floxuridine; D002110:Caffeine; D004247:DNA; D003513:Cycloheximide
O vozmozhnoĭ indutsibel'noĭ prirode radiorezistentnogo sinteza DNK, stimulirovannogo v kletkakh deĭstviem 5-ftordezoksiuridina.