Cerebral ventricular size and cognitive impairment in depression.
Twenty-one patients with major affective disorder were given the Halstead-Reitan Category Test and had CT brain scans performed in order to measure ventricular-brain ratio (VBR). A significant correlation between ventricular size and cognitive impairment was found. Possible pathophysiological mechanisms that might explain this relationship are discussed.
D000328:Adult; D000367:Age Factors; D001714:Bipolar Disorder / Q000473:pathology*; D001921:Brain / Q000000981:diagnostic imaging*; D014695:Cerebral Ventriculography; D003072:Cognition Disorders / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D003866:Depressive Disorder / Q000150:complications / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D009483:Neuropsychological Tests; D014057:Tomography, X-Ray Computed