title: Local thrombolysis in femoropopliteal occlusion: early and late results.
abstract: The early and late results of local thrombolysis with low-dose streptokinase followed by balloon dilatation in 64 patients with an occluded femoropopliteal artery are reviewed. The primary success rate was 77% for the native arteries; it was higher (80%) for short (less than 10 cm) as compared with long occlusion (40%) and for patients with claudication as compared with those with advanced ischemia (89% versus 48%). Eleven complications were observed in 10 patients, most frequently a local hematoma at the puncture site. Ascending thrombosis and absence of lysis or incomplete lysis were the main reasons for failure. The cumulative patency rate after 1 and 2 years follow-up was 87% and 82%, respectively.
mesh_terms: D000800:Angioplasty, Balloon; D003131:Combined Modality Therapy; D005260:Female; D005263:Femoral Artery / Q000187:drug effects; D005500:Follow-Up Studies; D006801:Humans; D007383:Intermittent Claudication / Q000628:therapy; D008297:Male; D011150:Popliteal Artery / Q000187:drug effects; D012008:Recurrence; D013300:Streptokinase / Q000008:administration & dosage*; D013927:Thrombosis / Q000628:therapy*
chemical_list: D013300:Streptokinase