A clinical and epidemiological study of an epidemic of non-A non-B hepatitis in Rangoon.
A total of 519 cases of viral hepatitis were admitted to the Infectious Diseases Hospital from June to October 1982 during an epidemic in Rangoon; 399 cases were found to be hepatitis non-A non-B, 84 cases were hepatitis B and 36 cases were hepatitis A. A clinical study was done of the 399 non-A non-B hepatitis cases. Also a prospective study of 434 households made up of 217 non-A non-B hepatitis cases with their families, together with 217 matched control families were followed up for a period of seven months to detect secondary cases among the family members. Non-A non-B hepatitis was found to occur most in adults of 20-40 years. Non-A non-B hepatitis is indistinguishable from the other two types of viral hepatitis. Case fatality rate was the highest in pregnant women with non-A non-B hepatitis. The field study suggested non-A non-B hepatitis can be transmitted by intrafamily spread. No evidence of sexual or syringe transmission of non-A non-B hepatitis was found.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D005260:Female; D006506:Hepatitis A / Q000453:epidemiology; D006509:Hepatitis B / Q000453:epidemiology; D006526:Hepatitis C / Q000453:epidemiology* / Q000235:genetics / Q000401:mortality / Q000635:transmission; D006525:Hepatitis, Viral, Human / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D002052:Myanmar; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000401:mortality; D012737:Sex Factors