Long-term remission of pure red cell aplasia after plasma exchange and lymphocytapheresis.
A 57-year-old man with idiopathic pure red cell aplasia went into remission after plasma exchange. He relapsed after 5 months and then failed to respond to treatment with intensive plasma exchange and immunosuppressive agents. Because of a high proportion of T-suppressor cells in the peripheral blood he was treated with lymphocytapheresis in addition to the previous treatment. The patient achieved a long-term haematological remission which has now persisted for more than 3 yr.
D003520:Cyclophosphamide / Q000627:therapeutic use; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D010951:Plasma Exchange; D010956:Plasmapheresis; D012010:Red-Cell Aplasia, Pure / Q000473:pathology / Q000628:therapy*; D050378:T-Lymphocytes, Regulatory / Q000473:pathology
D003520:Cyclophosphamide