title: Effect of tumour regression on serum and tissue copper concentration in mice bearing induced fibrosarcoma.
abstract: Serum and tissue copper concentration was determined in mice bearing induced fibrosarcoma after successful chemotherapeutic treatment. The results showed a significant depression in copper concentration in the serum and tumour tissue after treatment with anti-cancer drugs. However, the liver copper concentration showed no significant change in treated groups of mice compared to before treatment.
mesh_terms: D000818:Animals; D003300:Copper / Q000097:blood / Q000378:metabolism*; D005354:Fibrosarcoma / Q000188:drug therapy* / Q000378:metabolism; D005472:Fluorouracil / Q000627:therapeutic use*; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D051379:Mice; D008805:Mice, Inbred A; D016685:Mitomycin; D008937:Mitomycins / Q000627:therapeutic use*
chemical_list: D008937:Mitomycins; D016685:Mitomycin; D003300:Copper; D005472:Fluorouracil