Distribution of the methyl acceptor proteins within platelet granules.
Fractionation of platelet alpha-granules and dense bodies demonstrated that methyl acceptor proteins (MAP) were present in the alpha-granule fractions, but seemed to be low or absent in the dense body fraction. MAP activity in four intragranular proteins (albumin, fibrinogen, beta-thromboglobulin and platelet derived growth factor) was low or absent and could not explain the difference in methyl acceptor proteins distribution between alpha-granules and dense bodies.
D000255:Adenosine Triphosphate / Q000378:metabolism; D001426:Bacterial Proteins; D001792:Blood Platelets / Q000378:metabolism*; D003594:Cytoplasmic Granules / Q000378:metabolism*; D005340:Fibrinogen / Q000378:metabolism; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism*; D000072236:Methyl-Accepting Chemotaxis Proteins; D009638:Norepinephrine / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism; D012709:Serum Albumin / Q000378:metabolism; D013347:Subcellular Fractions / Q000378:metabolism; D014018:Tissue Distribution; D001620:beta-Thromboglobulin / Q000378:metabolism
D001426:Bacterial Proteins; D008565:Membrane Proteins; D000072236:Methyl-Accepting Chemotaxis Proteins; D012709:Serum Albumin; D001620:beta-Thromboglobulin; D012701:Serotonin; D000255:Adenosine Triphosphate; D005340:Fibrinogen; D009638:Norepinephrine