[Effect of Ginkgo biloba extract on arteriolar spasm in rabbits].
Injectable Ginkgo biloba extract, administered intravenously to rabbits, suppressed the vasospasm induced by the topic application of autologous serum on brain surface. This effect was dose-dependent as for as the normalization of the arterial diameter and duration of spasm were concerned. In animals previously treated with oral Ginkgo biloba extract, the almost complete disappearance of spasm was observed at intervals of time similar to those observed after intravenous injection.
D000284:Administration, Oral; D000818:Animals; D001160:Arterioles / Q000187:drug effects; D001921:Brain / Q000098:blood supply; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D005260:Female; D007106:Immune Sera / Q000494:pharmacology; D007275:Injections, Intravenous; D002546:Ischemic Attack, Transient / Q000139:chemically induced / Q000188:drug therapy*; D008297:Male; D010936:Plant Extracts / Q000627:therapeutic use; D010946:Plants, Medicinal; D011817:Rabbits; D013997:Time Factors; D014197:Trees
D007106:Immune Sera; D010936:Plant Extracts
Effet de l'extrait de Ginkgo biloba sur le spasme artériolaire chez le lapin.