title: The first reported case of Down syndrome in the Southern California Fertility Institute's in vitro fertilization and embryo transfer program.
abstract: The first case of a genetic abnormality in a 3-year in vitro fertilization and embryo transfer program was diagnosed after routine amniocentesis of a 38-year-old patient. The G-banded karyotype analysis gave 47, XY, +21, which constitutes an abnormal chromosome pattern consistent with Down syndrome.
mesh_terms: D000328:Adult; D004314:Down Syndrome; D004624:Embryo Transfer; D005307:Fertilization in Vitro; D006801:Humans; D007621:Karyotyping; D008596:Menotropins
chemical_list: D008596:Menotropins