title: beta-Endorphin: intranasal administration increases the serum prolactin level in monkey.
abstract: Human beta-endorphin has been administered by nasal spray technique at a dose of 0.02 mg per kg in female bonnet monkeys. A significant increase of serum prolactin levels was observed within 30 min and maintained up to 60 min. In the same dose, intravenous injections of the hormone caused a marginal increase of prolactin levels only after 60 min. It was concluded that administration of beta-endorphin by nasal spray is more effective than the intravenous injection.
mesh_terms: D000281:Administration, Intranasal; D000818:Animals; D004723:Endorphins / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D006801:Humans; D007275:Injections, Intravenous; D008255:Macaca radiata; D011388:Prolactin / Q000097:blood*; D001615:beta-Endorphin
chemical_list: D004723:Endorphins; D001615:beta-Endorphin; D011388:Prolactin