[Effect of fragments E and D on the plasmin hydrolysis of the fibrin clot].
It was found that fragments E (Mr = 45 000), DH (Mr = 95 000) and DL (Mr = 82 000) decrease the rate of plasmin hydrolysis of fibrin that is not cross-linked with factor XIII; the most effective inhibitor is fragment DL. The Kd values for the interactions of fragments E, DH and DL with plasmin are equal to 0.15, 0.4 and 0.04 microM, respectively.
D001780:Blood Coagulation Tests; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis* / Q000494:pharmacology*; D005341:Fibrinolysin / Q000032:analysis*; D006801:Humans; D006868:Hydrolysis; D066298:In Vitro Techniques
D005338:Fibrin Fibrinogen Degradation Products; C015214:fibrinogen D fragment; C018543:fibrinogen fragment E; D005341:Fibrinolysin
Izuchenie vliianiia fragmentov E i D na plazminovyĭ gidroliz fibrinovogo sgustka.