Plasma levels of atrial natriuretic peptide (ANP) in volume expanded patients: response to fluid removal by continuous pump driven hemofiltration.
Circulating amounts of human atrial natriuretic peptide (hANP) are elevated in congestive heart failure and renal failure. Stretching of cardiac atria, due to volume expansion associated with these diseases, is widely accepted to be the predominant stimulus for release of the hormone. Measurements of hemodynamic parameters as well as plasma concentrations of ANP in the right cardiac atrium, pulmonary artery, radial artery and vena cava superior, before and after continuous veno-venous hemofiltration (CVVH) of critically ill volume expanded patients, proved that ANP might be a useful indicator of fluid balance in these patients.
D009320:Atrial Natriuretic Factor / Q000097:blood*; D001769:Blood; D006333:Heart Failure / Q000097:blood; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood; D014462:Ultrafiltration; D014883:Water-Electrolyte Imbalance / Q000097:blood* / Q000628:therapy
D009320:Atrial Natriuretic Factor