title: Balloon dilatation of porcine bioprosthetic valves in the pulmonary position.
abstract: Balloon dilatation (BD) of bioprosthetic valves was investigated in vivo and in vitro. Four children with stenotic bioprosthetic porcine valves in the pulmonary position underwent BD of the valve 10 to 24 months after its insertion. Average valve gradient was reduced from 47.5 to 27 mm Hg. Obstruction at the conduit-branch pulmonary artery connection became apparent after dilatation of the valve. These distal stenoses were also dilated. BD technique was tested in vitro with the use of nonstenotic valves in fresh conduits. No damage to the valve or to the conduit was found when oversized balloons were used in a standard fashion or intentionally inflated until rupture. It is concluded that conduit replacement may be deferred by balloon dilatation of obstructed biological valves and/or a stenotic conduit-pulmonary artery anastomosis.
mesh_terms: D000800:Angioplasty, Balloon; D000818:Animals; D001021:Aortic Valve; D001705:Bioprosthesis; D002648:Child; D002675:Child, Preschool; D003251:Constriction, Pathologic / Q000473:pathology / Q000628:therapy; D004452:Echocardiography; D006350:Heart Valve Prosthesis; D006801:Humans; D007223:Infant; D011666:Pulmonary Valve Stenosis / Q000628:therapy*; D013552:Swine