title: The FI gene product of bacterial virus Lambda is related to the E. coli chromosomal protein NS2 and is involved in intracellular DNA organization.
abstract: A likely function of the Lambda FI gene product (gpFI) is condensation of developmental forms of the bacteriophage DNA in the host cell. Several characteristics of gpFI support this hypothesis: it is similar in its structure and properties to E. coli NS proteins whose involvement in the bacterial DNA condensation has been established and it comigrates with DNA during fractionation of host cell lysate through a sucrose gradient.
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000032:analysis / Q000502:physiology*; D010582:Bacteriophage lambda / Q000502:physiology*; D002467:Cell Nucleus / Q000648:ultrastructure; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004247:DNA / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000032:analysis / Q000502:physiology*; D004591:Electrophoresis, Polyacrylamide Gel; D004926:Escherichia coli / Q000032:analysis / Q000235:genetics* / Q000648:ultrastructure; D029968:Escherichia coli Proteins; D005814:Genes, Viral; D020904:Glia Maturation Factor; D008970:Molecular Weight; D009419:Nerve Tissue Proteins / Q000032:analysis / Q000502:physiology*; D012270:Ribosomes / Q000378:metabolism; D012689:Sequence Homology, Nucleic Acid
chemical_list: D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; D029968:Escherichia coli Proteins; D020904:Glia Maturation Factor; D009419:Nerve Tissue Proteins; C048904:chromosomal protein NS2, E coli; C040330:histone-like protein HU, bacteria; D004247:DNA