[Laryngeal edema after extubation. Do corticosteroids play a role in its prevention?].
The role of corticosteroids in the prevention of post-extubation laryngeal oedema was evaluated in a randomized study of 276 patients under mechanical ventilation. Fifty per cent of the patients received methylprednisolone 40 mg intramuscularly and intravenously. The nasotracheal tubes used had a large volume, low-pressure balloon. Laryngeal oedema, confirmed by laryngoscopy, occurred in six patients (2%), 4 of whom were in the corticosteroid-treated group, and required immediate reintubation in 4 cases. Thus, the incidence of laryngeal oedema was not modified by corticosteroids. Regular prescription of corticosteroids does not seem to be useful before extubation of patients intubated with large volume, low-pressure balloon tubes.
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal / Q000009:adverse effects*; D007819:Laryngeal Edema / Q000209:etiology / Q000517:prevention & control*; D007828:Laryngoscopy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012121:Respiration, Artificial
D000305:Adrenal Cortex Hormones
Cedème laryngé après extubation. Les corticoïdes ont-ils un rôle dans sa prévention?