Asymmetry in D-2 binding in female rat striata.
An asymmetry in D-2 receptor densities (Bmax) measured by [3H]N-methyl spiperone binding was found in striata from female Sprague-Dawley rats. The D-2 Bmax on the right side was on average 40% greater than the D-2 Bmax on the left side. This asymmetry is greater in magnitude and opposite in direction to that reported for males and is independent of directional preference exhibited during nocturnal circling.
D000818:Animals; D001931:Brain Mapping; D003342:Corpus Striatum / Q000378:metabolism*; D004292:Dominance, Cerebral / Q000502:physiology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D008297:Male; D009043:Motor Activity / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D011954:Receptors, Dopamine / Q000378:metabolism*; D017448:Receptors, Dopamine D2; D012737:Sex Factors; D013134:Spiperone / Q000031:analogs & derivatives / Q000378:metabolism
D011954:Receptors, Dopamine; D017448:Receptors, Dopamine D2; D013134:Spiperone; C039167:3-N-methylspiperone