[Rheumatic activity and clinico-pathologic dissociation. Clinical and pathologic parameters in rheumatic heart disease].
We studied atrial appendages and valvular apparatus from patients undergoing cardiac surgery for rheumatic heart disease, looking for active histologic lesions. After reviewing 673 specimens (1980-1985) we studied two groups: 31 cases with Aschoff nodules or ill-differentiated histopathological lesions, and 31 cases, without tissular inflammatory abnormalities. In the former we found 8 cases with suspected clinical activity in a 3 months period before surgery, in the latter only 2 cases had similar findings. The Jones criteria are not useful for recognizing rheumatic activity among patients with chronic rheumatic heart disease, there is no clinical-histopathological correlations and it is possible that chronic inflammation occurs at the heart as an organ-limited condition.
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D005260:Female; D006325:Heart Atria / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000473:pathology; D012214:Rheumatic Heart Disease / Q000473:pathology*; D012215:Rheumatic Nodule / Q000473:pathology*
Actividad reumática y disociación clínico-patológica. Parámetros clinicos y patólogicos en la cardiopatía reumática.