title: Red cell phosphoglucomutase (PGM1) subtypes in Egyptians.
abstract: The polymorphism of the human red cell phosphoglucomutase 1 (PGM1) in samples from Egyptians (n = 134) was investigated using isoelectric focusing in thin-layer polyacrylamide gel. In the studied population samples nine common phenotypes were observed, and the calculated frequencies for the genes PGM1+1, PGM1-1, PGM2+1 and PGM2-1 were 0.6381, 0.0821, 0.2201 and 0.0597, respectively. The observed and expected phenotypes provide a good fit to Hardy-Weinberg equilibrium. The four alleles system will increase the probability of excluding a man falsely accused of paternity to 30% as compared with 16% if the two alleles system is used.
mesh_terms: D004534:Egypt; D004591:Electrophoresis, Polyacrylamide Gel; D004912:Erythrocytes / Q000201:enzymology*; D005787:Gene Frequency; D006801:Humans; D007525:Isoelectric Focusing; D010641:Phenotype; D010733:Phosphoglucomutase / Q000032:analysis / Q000097:blood* / Q000235:genetics; D011110:Polymorphism, Genetic
chemical_list: D010733:Phosphoglucomutase