Basomedial amygdaloid lesions and p-CPA induced muricidal aggression.
Bilateral lesions of basomedial amygdaloid nuclei are capable of significantly inhibiting muricidal aggression induced by oral p-chlorophenylalanine (p-CPA) in male rats. Rats lesioned in extra-amygdaloid structures or sham-lesioned show the usual p-CPA-induced muricidal activity, which ranges from 70 to 80% of treated animals. The results obtained indicate that basomedial amygdaloid nuclei play an important role in regulating p-CPA-induced muricidal aggression, even though the effect lasts for a relatively limited period of time. This fact is probably due to the intervention of still unidentified compensatory mechanisms.
D000679:Amygdala / Q000378:metabolism / Q000502:physiology*; D000818:Animals; D001070:Appetitive Behavior / Q000502:physiology*; D010134:Fenclonine / Q000494:pharmacology*; D008297:Male; D051379:Mice; D011235:Predatory Behavior / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000378:metabolism; D012702:Serotonin Antagonists / Q000494:pharmacology
D012702:Serotonin Antagonists; D012701:Serotonin; D010134:Fenclonine