title: Aspects of mycobacterial response to beryllate ions in vitro.
abstract: Comparative growth measurements of the mycobacterial species Mycobacterium phlei and Mycobacterium tuberculosis were carried out with liquid cultures supplemented with oxalatoberyllate ions in the concentration range 0-120 microM Be. For both species, the effect of beryllium on specific growth parameters can be represented by a Be concentration-dependent, exponential expression. Evidence for beryllium binding to cellular phospholipids (approximately 15% of Be uptake) is provided by 31P NMR spectroscopy, thin-layer chromatography and atomic absorption spectrometry.
mesh_terms: D001608:Beryllium / Q000494:pharmacology*; D002855:Chromatography, Thin Layer; D009161:Mycobacterium / Q000187:drug effects*; D009168:Mycobacterium phlei / Q000187:drug effects; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D009391:Nephelometry and Turbidimetry
chemical_list: D001608:Beryllium