[Systemic scleroderma. Contribution of esophageal manometry].
Oesophageal motor function was studied by oesophageal manometry in 48 patients with progressive systemic sclerosis: 25 with proximal scleroderma and 23 with diffuse scleroderma. Oesophageal lesions were noted in 70% (74% in diffuse scleroderma; 64% in proximal scleroderma). Classical manometric signs of scleroderma were found in only 31% of patients. Peristaltic modifications might begin at the junction of the two muscular coats, since a four centimeter long aperistaltic suspended area was noted in that region in 20% of patients, especially in the proximal scleroderma group. Oesophageal motility and low lower oesophageal sphincter pressure account for the gastro-oesophageal reflux and may compromise respiratory function, as suggested by the high frequency of concurrent oesophageal and respiratory dysfunction in diffuse scleroderma. Systematic prevention of gastro-oesophageal reflux should perhaps be advocated as soon as abnormalities in oesophageal motility are diagnosed.
D000293:Adolescent; D000328:Adult; D000368:Aged; D004935:Esophageal Diseases / Q000209:etiology; D004947:Esophagus / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000209:etiology; D008297:Male; D008365:Manometry; D008875:Middle Aged; D013902:Radiography, Thoracic; D012129:Respiratory Function Tests; D012595:Scleroderma, Systemic / Q000150:complications / Q000503:physiopathology*
Sclérodermie systémique. Apport de la manométrie oesophagienne.