[Bone marrow transplantation in the therapy of genetic diseases].
The technique of bone marrow transplantation (BMT) is now well established. Of now over 90 inborn errors of metabolism at least 45 have been treated by BMT. Among these some 35 have been proven to be curable by this procedure. The present paper reviews the respective literature and considers in particular the pertinent experiences of the Westminster Bone Marrow Transplantation Team.
D016026:Bone Marrow Transplantation; D002648:Child; D006087:Graft vs Host Reaction; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D007108:Immune Tolerance; D007153:Immunologic Deficiency Syndromes / Q000235:genetics / Q000601:surgery*; D008213:Lymphocyte Activation; D007959:Lymphocyte Culture Test, Mixed; D008661:Metabolism, Inborn Errors / Q000235:genetics / Q000601:surgery*; D014181:Transplantation Immunology
D006680:HLA Antigens
Knochenmarktransplantation in der Therapie genetischer Erkrankungen.