Primary pulmonary hypertension in childhood: a report of two brothers.
We report 2 cases of primary pulmonary hypertension in brothers, 6 and 3 years old. Their lungs contained numerous plexiform vascular lesions. The literature is reviewed involving familial cases, especially those in which siblings were affected. Several of these cases lack the pathological verification necessary for acceptance as examples of plexogenic pulmonary arteriopathy.
D006332:Cardiomegaly / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D006976:Hypertension, Pulmonary / Q000235:genetics / Q000473:pathology*; D006984:Hypertrophy; D008297:Male; D011651:Pulmonary Artery / Q000473:pathology