title: Netobimin in drinking water for treatment of bovine parasitic bronchitis: a field experiment.
abstract: Lungworm-infected seeder calves were used on four 1.41 ha paddocks to ensure that groups of 11 calves would be exposed to a heavy challenge with Dictyocaulus viviparus. By the 39th day after turnout there was a serious episode of respiratory disease and a diagnosis of parasitic bronchitis was confirmed by post mortem and faecal examination. One group of trial calves was treated with netobimin administered in the drinking water at 2.8 mg/kg/day for seven consecutive days; another group received the same treatment supplemented with flunixin meglumine at 2.2 mg/kg/day for three days; a third group was given a single oral dose of 7.5 mg netobimin/kg; only emergency treatments were given to calves in the control group. The clinical response to the drinking water treatments was highly satisfactory and better than the response to the single oral treatment.
authors.affiliation: Department of Veterinary Pathology, Royal Veterinary College, University of London, Hatfield, Hertfordshire.
authors.forename: D E
authors.initials: DE
authors.lastname: Jacobs
authors.forename: J G
authors.initials: JG
authors.lastname: Pilkington
authors.forename: M T
authors.initials: MT
authors.lastname: Fox
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001991:Bronchitis / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy* / Q000469:parasitology; D004022:Dictyocaulus Infections / Q000188:drug therapy*; D006146:Guanidines / Q000008:administration & dosage / Q000627:therapeutic use*; D008174:Lung Diseases, Parasitic / Q000188:drug therapy / Q000662:veterinary*; D014881:Water Supply
chemical_list: D006146:Guanidines; C049626:netobimin