title: Mesoblastic nephroma contains fibronectin but lacks laminin.
abstract: Non-metastatic mesoblastic nephromas from four young children were shown to contain fibronectin but not laminin using an immunoperoxidase staining procedure. In contrast, one metastasising spindle celled sarcomatous tumour from a neonate was laminin positive. During embryogenesis primitive nephrogenic mesenchyme contains only fibronectin and no laminin; metanephric blastema (permanent kidney) is positive for laminin. The staining for fibronectin and laminin may help to ascertain the histogenesis of different types of renal tumour.
authors.forename: S
authors.initials: S
authors.lastname: Kumar
authors.forename: H B
authors.initials: HB
authors.lastname: Marsden
authors.forename: T
authors.initials: T
authors.lastname: Carr
authors.forename: R
authors.initials: R
authors.lastname: Kodet
mesh_terms: D005260:Female; D005353:Fibronectins / Q000032:analysis*; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D007680:Kidney Neoplasms / Q000032:analysis* / Q000473:pathology; D007797:Laminin / Q000032:analysis*; D008297:Male; D012509:Sarcoma / Q000032:analysis; D009396:Wilms Tumor / Q000032:analysis* / Q000473:pathology
chemical_list: D005353:Fibronectins; D007797:Laminin