title: Treatment of Alzheimer's disease with a synthetic ACTH 4-9 analog.
abstract: The synthetic ACTH 4-9 analog, Org 2766, was administered to 77 Alzheimer's patients for 6 months in a double-blind, placebo-controlled study. Although Org 2766 was tolerated well, no significant effect of Org 2766 could be demonstrated in terms of rating scales or cognitive functions.
authors.forename: H
authors.initials: H
authors.lastname: Soininen
authors.forename: T
authors.initials: T
authors.lastname: Koskinen
authors.forename: E L
authors.initials: EL
authors.lastname: Helkala
authors.forename: R
authors.initials: R
authors.lastname: Pigache
authors.forename: P J
authors.initials: PJ
authors.lastname: Riekkinen
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000368:Aged; D000544:Alzheimer Disease / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D010446:Peptide Fragments / Q000627:therapeutic use*; D010919:Placebos
chemical_list: D010446:Peptide Fragments; D010919:Placebos; C013765:Org 2766; D000324:Adrenocorticotropic Hormone