Polymorphous drug eruption due to nifedipine.
A patient who underwent coronary bypass surgery and was treated with nifedipine subsequently developed an erysipelaslike erythematous itching plaque on both shins. Histopathologic examination of a biopsy specimen from the area showed findings compatible with a lichen-planus-like drug eruption. An awareness of varied skin reactions produced by nifedipine may reduce the suffering of patients and help prevent unnecessary local and general treatments.
Leibovici
V
V
Department of Dermatology, Hadassah Ein Karem Hospital, Jerusalem, Israel.
Zlotogorski
A
A
Heyman
A
A
Kanner
A
A
Melmed
R N
RN
D003875:Drug Eruptions / Q000209:etiology*; D006801:Humans; D009543:Nifedipine / Q000009:adverse effects*
D009543:Nifedipine