Two distinctive transforming DNA regions on the canine adenovirus type 1 genome.
By transfecting cloned DNA fragments of canine adenovirus type 1, a novel transforming region of mammalian adenovirus was demonstrated inside the viral genome. Besides the left-end SmaI-D fragment (left 17.2%), an internally located SmaI-E fragment (17.2-28.7%) of canine adenovirus type 1 was found to transform primary rat kidney cells.
Yamashita
T
T
Ren
C S
CS
Yoshida
K
K
Shinagawa
M
M
Masuda
K
K
Fujinaga
K
K
D006516:Adenoviruses, Canine / Q000235:genetics*; D000818:Animals; D002472:Cell Transformation, Viral; D004279:DNA, Viral / Q000032:analysis*; D009693:Nucleic Acid Hybridization; D010957:Plasmids; D051381:Rats; D014162:Transfection
D004279:DNA, Viral