Prospective randomized trial of polytetrafluoroethylene and Dacron aortic prosthesis. I. Perioperative results.
Over a two year period 80 patients were entered into a prospective randomized trial comparing polytetrafluoroethylene (PTFE) and Dacron infrarenal aortic reconstructions. Fifty-four patients were treated for aneurysm (30 single tubed grafts; 24 bifurcation grafts), and 26 patients were treated for occlusive disease (26 bifurcation grafts). The groups were matched for age, sex and preoperative risk factors. Five patients died after operation (6.3%) including two from hemorrhage, but there were no significant differences in mortality and morbidity between the PTFE and Dacron groups. The volume of blood lost at operation (1930 +/- 1340 ml, all patients); the volume of blood transfused (2.98 +/- 2.43 units); the volume of crystalloids infused (3050 +/- 1390 ml); the intraoperative heparin dosage (67.9 +/- 20.5 mg); the clamp time (71.6 +/- 34.5 min); and the total operating time (228.1 +/- 78.3 min) also showed no significant differences between PTFE and Dacron. The ankle systolic pressure index rose more for PTFE (0.96 +/- 0.24) than for Dacron (0.82 +/- 0.20; P less than 0.002) at the time of discharge. This partially reflects a difference in the index between the groups before operation (PTFE 0.79 +/- 0.30; Dacron 0.72 +/- 0.32), but it may also indicate that PTFE is less thrombogenic than Dacron.
Lord
R S
RS
Surgical Professorial Unit, St. Vincent's Hospital, Sydney, Australia.
Nash
P A
PA
Raj
B T
BT
Stary
D L
DL
Graham
A R
AR
Hill
D A
DA
Tracy
G D
GD
Goh
K H
KH
D000368:Aged; D001018:Aortic Diseases / Q000601:surgery*; D001794:Blood Pressure; D001807:Blood Vessel Prosthesis / Q000009:adverse effects / Q000401:mortality; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011093:Polyethylene Terephthalates; D011138:Polytetrafluoroethylene; D011446:Prospective Studies; D011897:Random Allocation; D012307:Risk Factors
D011093:Polyethylene Terephthalates; D011138:Polytetrafluoroethylene