title: Cervical myelography with iohexol and metrizamide. A randomized double blind clinical study.
abstract: A randomized double-blind study with iohexol and metrizamide in cervical myelography was performed in 100 patients. The concentration of the contrast medium was 240 mg I/ml. The image quality was equal with both contrast media. Forty-two per cent of the patients receiving iohexol had side effects (headache 22%, nausea 6%, vomiting 2% and mental reactions 6%), in contrast to 80 per cent of the patients receiving metrizamide (headache 56%, nausea 34%, vomiting 24% and mental reactions 26%). The majority of side effects appeared within 6 hours after injection of contrast medium. Two patients had a late onset of symptoms - one in each group. Once appearing, the side effects tended to be equally severe.
authors.affiliation: Roentgen Division, Töölö Hospital, Helsinki University Central Hospital, Finland.
authors.forename: A
authors.initials: A
authors.lastname: Servo
authors.forename: M
authors.initials: M
authors.lastname: Porras
authors.forename: J
authors.initials: J
authors.lastname: Jääskinen
authors.forename: A
authors.initials: A
authors.lastname: Virta
authors.forename: E M
authors.initials: EM
authors.lastname: Laasonen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007472:Iohexol / Q000009:adverse effects; D008297:Male; D008793:Metrizamide / Q000009:adverse effects; D008875:Middle Aged; D009192:Myelography
chemical_list: D007472:Iohexol; D008793:Metrizamide