Hormonal profile in benign breast disease. Endocrine status of cyclical mastalgia patients.
Plasma levels of prolactin, before and after TRH stimulation, progesterone, estradiol, sex-hormone-binding-globulin, androstenedione, testosterone and dehydroepiandrosterone-sulphate were determined in a group of women with benign breast disease and in control group, in order to correlate a possible hormonal disorder to breast pathology. The hormonal pattern in the patients with benign breast disease was characterized by an increased responsiveness of lactotrophes to TRH stimulation and by higher levels of sex hormone binding globulin, probably sustained by an underlying hyperestrogenism.
Parlati
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Istituto di Clinica Ostetrica e Ginecologica, Università Cattolica del S. Cuore, Roma, Italy.
Travaglini
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A
Liberale
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I
Menini
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E
Dell'Acqua
S
S
D000305:Adrenal Cortex Hormones / Q000097:blood*; D000328:Adult; D000735:Androstenedione / Q000097:blood; D001941:Breast Diseases / Q000097:blood*; D003687:Dehydroepiandrosterone / Q000031:analogs & derivatives / Q000097:blood; D019314:Dehydroepiandrosterone Sulfate; D004958:Estradiol / Q000097:blood; D005260:Female; D006801:Humans; D008183:Luteal Phase; D010907:Pituitary Hormones / Q000097:blood*; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood; D012738:Sex Hormone-Binding Globulin / Q000032:analysis; D013739:Testosterone / Q000097:blood; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology
D000305:Adrenal Cortex Hormones; D010907:Pituitary Hormones; D012738:Sex Hormone-Binding Globulin; D013739:Testosterone; D000735:Androstenedione; D003687:Dehydroepiandrosterone; D011374:Progesterone; D004958:Estradiol; D019314:Dehydroepiandrosterone Sulfate; D013973:Thyrotropin-Releasing Hormone; D011388:Prolactin