Papillon-Lefèvre syndrome. Successful treatment with oral retinoids in three patients.
Papillon-Lefèvre syndrome is a rare autosomal recessive disorder of palmoplantar keratinization in which there is a unique association of the palmoplantar hyperkeratosis and premature loss of both deciduous and permanent teeth. We report three patients with papillon-lefèvre syndrome who showed a remarkable degree of improvement after treatment with an oral retinoid.
el Darouti
M A
MA
Department of Dermatology, Cairo University Faculty of Medicine, Egypt.
Al Raubaie
S M
SM
Eiada
M A
MA
D000284:Administration, Oral; D005050:Etretinate / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000188:drug therapy*; D010214:Papillon-Lefevre Disease / Q000188:drug therapy*
D005050:Etretinate