title: Anaerobic bacteria and herpes simplex virus in genital ulceration.
abstract: Of 91 patients with genital ulceration, herpes simplex virus was isolated from 52 (57%) and Haemophilus ducreyi from 12 (13%); none had syphilis. The difference in incidence of other aerobes in patients and controls was not significant. Anaerobes, predominantly Bacteroides spp, were isolated from a large proportion (77%) of men and women patients with ulcers but from few control men. The most common anaerobic species were B asaccharolyticus and B ureolyticus, with fewer isolates of the melaninogenicus/oralis group. The bacterial flora of herpetic and non-herpetic ulcers were similar, but Candida albicans was isolated significantly more often from non-herpetic ulcers. Anaerobic bacteria may contribute to the pathogenesis of genital ulcers.
authors.forename: A N
authors.initials: AN
authors.lastname: Masfari
authors.forename: G R
authors.initials: GR
authors.lastname: Kinghorn
authors.forename: S
authors.initials: S
authors.lastname: Hafiz
authors.forename: I G
authors.initials: IG
authors.lastname: Barton
authors.forename: B I
authors.initials: BI
authors.lastname: Duerden
mesh_terms: D000293:Adolescent; D000328:Adult; D001421:Bacteria, Anaerobic / Q000302:isolation & purification*; D002176:Candida albicans / Q000302:isolation & purification; D005260:Female; D005831:Genital Diseases, Female / Q000382:microbiology*; D005832:Genital Diseases, Male / Q000382:microbiology*; D006191:Haemophilus ducreyi / Q000302:isolation & purification; D006558:Herpes Genitalis / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018139:Simplexvirus / Q000302:isolation & purification*; D014210:Treponema pallidum / Q000302:isolation & purification; D014456:Ulcer / Q000382:microbiology