Neuroendocrine islet cell tumour producing gastrin and ACTH in a patient with calcifying chronic pancreatitis.
A patient with a calcifying chronic pancreatitis was found to have a neuroendocrine islet cell tumour (a previously unreported association). The tumour secreted both gastrin and ACTH leading to clinical manifestations of both the Zollinger-Ellison syndrome and Cushing's syndrome.
Allison
M C
MC
Renfrew
C C
CC
Webb
W J
WJ
Chappell
M E
ME
Pounder
R E
RE
D007516:Adenoma, Islet Cell / Q000150:complications* / Q000378:metabolism; D000324:Adrenocorticotropic Hormone / Q000378:metabolism; D000368:Aged; D002114:Calcinosis / Q000150:complications*; D002908:Chronic Disease; D005755:Gastrins / Q000378:metabolism; D006801:Humans; D008297:Male; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000378:metabolism; D010195:Pancreatitis / Q000150:complications*; D015043:Zollinger-Ellison Syndrome / Q000150:complications
D005755:Gastrins; D000324:Adrenocorticotropic Hormone