title: Neuroendocrine islet cell tumour producing gastrin and ACTH in a patient with calcifying chronic pancreatitis.
abstract: A patient with a calcifying chronic pancreatitis was found to have a neuroendocrine islet cell tumour (a previously unreported association). The tumour secreted both gastrin and ACTH leading to clinical manifestations of both the Zollinger-Ellison syndrome and Cushing's syndrome.
authors.forename: M C
authors.initials: MC
authors.lastname: Allison
authors.forename: C C
authors.initials: CC
authors.lastname: Renfrew
authors.forename: W J
authors.initials: WJ
authors.lastname: Webb
authors.forename: M E
authors.initials: ME
authors.lastname: Chappell
authors.forename: R E
authors.initials: RE
authors.lastname: Pounder
mesh_terms: D007516:Adenoma, Islet Cell / Q000150:complications* / Q000378:metabolism; D000324:Adrenocorticotropic Hormone / Q000378:metabolism; D000368:Aged; D002114:Calcinosis / Q000150:complications*; D002908:Chronic Disease; D005755:Gastrins / Q000378:metabolism; D006801:Humans; D008297:Male; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000378:metabolism; D010195:Pancreatitis / Q000150:complications*; D015043:Zollinger-Ellison Syndrome / Q000150:complications
chemical_list: D005755:Gastrins; D000324:Adrenocorticotropic Hormone