Gamma-radiation induced ADP-ribosyl transferase activity and mammalian longevity.
The levels of ADP-ribosyl transferase (ADPRT) activity following a standardized dose of 100 Gy gamma-radiation have been determined in leukocytes from 12 different mammalian species. Here, we report that the 100 Gy-induced levels of ADPRT correlated in a highly significant manner to the line spans of the mammals.
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D000246:Adenosine Diphosphate Ribose / Q000378:metabolism*; D000818:Animals; D004260:DNA Repair / Q000528:radiation effects*; D005720:Gamma Rays; D006801:Humans; D007962:Leukocytes / Q000378:metabolism; D008136:Longevity; D009702:Nucleoside Diphosphate Sugars / Q000378:metabolism*; D009713:Nucleotidyltransferases / Q000378:metabolism*; D011065:Poly(ADP-ribose) Polymerases; D013045:Species Specificity
D009702:Nucleoside Diphosphate Sugars; D000246:Adenosine Diphosphate Ribose; D011065:Poly(ADP-ribose) Polymerases; D009713:Nucleotidyltransferases