Primary irritant effect of 3,4,5-trichloropyridazine.
A primary irritant dermatitis to 3,4,5-trichloropyridazine was observed on the hands of a chemist after accidental exposure. Healing was rapid in comparison to a report on 3,4,6-trichloropyridazine toxicity. Prompt treatment with a potent topical corticosteroid, wet soaks, and an oral antihistamine brought resolution within 14 days.
Warshaw
T G
TG
Department of Dermatology, University of Medicine and Dentistry of New Jersey, Newark.
D000279:Administration, Cutaneous; D002990:Clobetasol / Q000627:therapeutic use; D003877:Dermatitis, Contact / Q000188:drug therapy / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000209:etiology; D004155:Diphenhydramine / Q000627:therapeutic use; D006801:Humans; D007509:Irritants; D008297:Male; D008875:Middle Aged; D011481:Protective Clothing; D011724:Pyridazines / Q000009:adverse effects*
D007509:Irritants; D011724:Pyridazines; C057049:3,4,5-trichloropyridazine; C048174:3,4,6-trichloropyridazine; D004155:Diphenhydramine; D002990:Clobetasol