title: Alpha globin gene rearrangements in Polynesians are not associated with malaria.
abstract: Using gene mapping, 16.3% of Polynesians were shown to have alpha thalassemia. These results are surprising since malaria is not found in Polynesia. Moreover, triplicated alpha gene rearrangements were identified in a further 7.7%, a frequency not seen in other populations.
authors.forename: R J
authors.initials: RJ
authors.lastname: Trent
authors.forename: K N
authors.initials: KN
authors.lastname: Mickleson
authors.forename: T
authors.initials: T
authors.lastname: Wilkinson
authors.forename: J
authors.initials: J
authors.lastname: Yakas
authors.forename: R
authors.initials: R
authors.lastname: Bluck
authors.forename: M
authors.initials: M
authors.lastname: Dixon
authors.forename: A W
authors.initials: AW
authors.lastname: Liley
authors.forename: H
authors.initials: H
authors.lastname: Kronenberg
mesh_terms: D002874:Chromosome Mapping; D004262:DNA Restriction Enzymes; D005312:Fetal Blood / Q000032:analysis; D005838:Genotype; D005914:Globins / Q000235:genetics*; D006801:Humans; D008288:Malaria / Q000097:blood / Q000235:genetics*; D011114:Polynesia; D013789:Thalassemia / Q000235:genetics
chemical_list: D005914:Globins; D004262:DNA Restriction Enzymes