title: Diagnostic differentiation between reactive and malignant lymphoid cells in serous effusions.
abstract: Lymphoid cell components in a total of 34 pleural and ascitic aspirates were investigated immunologically. The results indicate that reactive lymphocytes predominate in effusions from non-haemopoietic malignancies and benign conditions, while a significant proportion of fluids from patients with non-Hodgkins lymphoma show unequivocal evidence of lymphomatous involvement. Immunological typing of lymphocytes in serous effusions is a valuable adjunct to conventional methods of diagnosis particularly in those patients in whom invasive procedures are undesirable.
authors.affiliation: Department of Haematology, Bradford Royal Infirmary, U.K.
authors.forename: E J
authors.initials: EJ
authors.lastname: Johnson
authors.forename: C S
authors.initials: CS
authors.lastname: Scott
authors.forename: L A
authors.initials: LA
authors.lastname: Parapia
authors.forename: A N
authors.initials: AN
authors.lastname: Stark
mesh_terms: D001202:Ascitic Fluid / Q000276:immunology*; D005260:Female; D006689:Hodgkin Disease / Q000175:diagnosis; D006801:Humans; D007945:Leukemia, Lymphoid / Q000175:diagnosis; D007958:Leukocyte Count; D008214:Lymphocytes / Q000276:immunology*; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000276:immunology; D009369:Neoplasms / Q000276:immunology; D010996:Pleural Effusion / Q000276:immunology*; D011947:Receptors, Antigen, B-Cell / Q000032:analysis; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
chemical_list: D011947:Receptors, Antigen, B-Cell