title: CT of perineural tumor extension: pterygopalatine fossa.
abstract: Tumors of the oral cavity and paranasal sinuses can spread along nerves to areas apparently removed from the primary tumor. In tumors of the palate, sinuses, and face, this "perineural" spread usually involves the maxillary division of the trigeminal nerve. The pterygopalatine fossa is a pathway of the maxillary nerve and becomes a key landmark in the detection of neural metastasis by computed tomography (CT). Obliteration of the fat in the fossa suggests pathology. Case material illustrating neural extension is presented and the CT findings are described.
authors.forename: H D
authors.initials: HD
authors.lastname: Curtin
authors.forename: R
authors.initials: R
authors.lastname: Williams
authors.forename: J
authors.initials: J
authors.lastname: Johnson
mesh_terms: D000328:Adult; D003528:Carcinoma, Adenoid Cystic / Q000000981:diagnostic imaging / Q000556:secondary; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000556:secondary; D003390:Cranial Nerve Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D005260:Female; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging*; D018219:Histiocytoma, Benign Fibrous / Q000000981:diagnostic imaging / Q000556:secondary; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging / Q000556:secondary; D008297:Male; D008442:Maxillary Nerve; D008875:Middle Aged; D014057:Tomography, X-Ray Computed