Fluoride ions increase collagenase production by rabbit synovial fibroblasts.
Ionic fluoride is taken up by rabbit synovial fibroblasts in culture. The uptake was accompanied by an increased production of latent collagenase, and decreased activity of 5'-nucleotidase.
Jendryczko
A
A
Drózdz
M
M
D015720:5'-Nucleotidase; D000818:Animals; D004790:Enzyme Induction / Q000187:drug effects; D005347:Fibroblasts / Q000201:enzymology; D005459:Fluorides / Q000494:pharmacology*; D066298:In Vitro Techniques; D003012:Microbial Collagenase / Q000096:biosynthesis*; D009708:Nucleotidases / Q000378:metabolism; D011817:Rabbits; D012969:Sodium Fluoride / Q000494:pharmacology; D013582:Synovial Fluid / Q000201:enzymology*; D014357:Trypsin / Q000494:pharmacology
D012969:Sodium Fluoride; D009708:Nucleotidases; D015720:5'-Nucleotidase; D014357:Trypsin; D003012:Microbial Collagenase; D005459:Fluorides