[T-cell subpopulations and suppressor activity in atopic and infection-induced asthma].
We determined the T-lymphocyte subpopulations by means of monoclonal antibodies (CD 3, CD 4, CD 8) and the so-called suppressor index (increased lymphocyte stimulation after 24 h preincubation) in 20 patients with extrinsic asthma and in 18 patients with intrinsic asthma. In patients with extrinsic asthma we found an increase of ratio CD 4/CD 8. The short-living suppressor activity was significantly decreased in patients with intrinsic asthma.
Gamkrelidse
A
A
Staatlichen Medizinischen Institut Tbilissi.
Vogelsang
H
H
D000911:Antibodies, Monoclonal / Q000276:immunology; D001249:Asthma / Q000150:complications / Q000276:immunology*; D003141:Communicable Diseases / Q000150:complications / Q000276:immunology*; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology*; D013601:T-Lymphocytes / Q000145:classification / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*
D000911:Antibodies, Monoclonal
T-Zellsubpopulationen und Suppressoraktivität bei atopischem und infektbedingtem Asthma.