title: Secondary amyloidosis and cystic fibrosis. A morphological and histochemical study of five cases.
abstract: The pathological findings of five cases of amyloidosis associated with Cystic Fibrosis are reported. Rectal biopsy led to the diagnosis of amyloidosis in four patients. In three cases the diagnosis was confirmed at autopsy, with involvement of spleen, liver, kidneys, adrenal glands, thyroid and other organs. It seems that Secondary Amyloidosis provokes a significant, although rare, complication of Cystic Fibrosis as greater numbers of these patients survive into adulthood.
authors.affiliation: Serv. di Anatomia e Istologia Patologica, Ospedale Borgo Trento, Verona, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Bontempini
authors.forename: C
authors.initials: C
authors.lastname: Ghimenton
authors.forename: R
authors.initials: R
authors.lastname: Colombari
authors.forename: M
authors.initials: M
authors.lastname: Malena
authors.forename: P
authors.initials: P
authors.lastname: Iuzzolino
authors.forename: M
authors.initials: M
authors.lastname: Canciani
authors.forename: C
authors.initials: C
authors.lastname: Doglioni
authors.forename: L
authors.initials: L
authors.lastname: Sbabo
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000209:etiology / Q000473:pathology*; D001344:Autopsy; D001706:Biopsy; D002648:Child; D003550:Cystic Fibrosis / Q000150:complications / Q000473:pathology*; D005260:Female; D005881:Gingiva / Q000473:pathology; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D008297:Male; D012007:Rectum / Q000473:pathology