title: Peritonitis and massive granulocytic infiltration of the spleen in adult Still's disease.
abstract: A case of adult Still's disease is described which, in addition to the more common manifestations, also included abdominal discomfort. Upon laparoscopy, peritonitis was disclosed; a biopsy showed massive granulocytic infiltration of the spleen which could not be attributed to an infectious disease. The patient did not improve on conventional therapeutic modalities but required intensive combination therapy consisting of high dose acetylsalicylic acid, prednisone, and slow-reacting substances before entering remission.
authors.affiliation: I. Department of Internal Medicine, Johannes Gutenberg University Mainz, Fed. Rep. Germany.
authors.forename: T
authors.initials: T
authors.lastname: Poralla
authors.forename: T
authors.initials: T
authors.lastname: Hütteroth
authors.forename: W
authors.initials: W
authors.lastname: Mayet
authors.forename: K
authors.initials: K
authors.lastname: Gutfreund
authors.forename: E
authors.initials: E
authors.lastname: Hermann
authors.forename: G
authors.initials: G
authors.lastname: Gerken
authors.forename: H J
authors.initials: HJ
authors.lastname: Rumpelt
authors.forename: P
authors.initials: P
authors.lastname: Baum
authors.forename: K H
authors.initials: KH
authors.lastname: Meyer zum Büschenfelde
mesh_terms: D000293:Adolescent; D001171:Arthritis, Juvenile / Q000188:drug therapy / Q000473:pathology*; D001241:Aspirin / Q000627:therapeutic use; D001379:Azathioprine / Q000627:therapeutic use; D001706:Biopsy; D004359:Drug Therapy, Combination; D006098:Granulocytes / Q000473:pathology*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D010538:Peritonitis / Q000188:drug therapy / Q000473:pathology*; D011241:Prednisone / Q000627:therapeutic use; D013154:Spleen / Q000473:pathology*
chemical_list: D001379:Azathioprine; D001241:Aspirin; D011241:Prednisone