Malignant melanoma, benzoyl peroxide and acne: a pilot epidemiological case-control investigation.
A case-control study utilizing available medical records was carried out to investigate possible links between use of topical benzoyl peroxide for acne, and malignant melanoma. One hundred and fifty nine cases and 213 matched controls were used in the analysis which shows no significant association between the use of benzoyl peroxide and the occurrence of malignant melanoma, nor between the occurrence of acne and malignant melanoma.
Cartwright
R A
RA
Centre for Clinical Epidemiology, University of Leeds, U.K.
Hughes
B R
BR
Cunliffe
W J
WJ
D000152:Acne Vulgaris / Q000188:drug therapy*; D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D001585:Benzoyl Peroxide / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000139:chemically induced*; D010545:Peroxides / Q000009:adverse effects*; D010865:Pilot Projects; D012306:Risk; D012878:Skin Neoplasms / Q000139:chemically induced*
D010545:Peroxides; D001585:Benzoyl Peroxide