title: Circadian variations in radioligand binding to muscarine receptors in rat brain dependent upon endogenous agonist occupation.
abstract: Although total levels of muscarine receptors in the rat forebrain and brainstem are constant at different times of day, there are large circadian changes in the numbers and carbachol-affinities of unoccupied receptors, which appear to reflect varying levels of endogenous acetylcholine-receptor complexes and the activity of cholinergic synapses.
authors.forename: D C
authors.initials: DC
authors.lastname: Mash
authors.forename: D D
authors.initials: DD
authors.lastname: Flynn
authors.forename: L
authors.initials: L
authors.lastname: Kalinoski
authors.forename: L T
authors.initials: LT
authors.lastname: Potter
mesh_terms: D000109:Acetylcholine / Q000502:physiology; D000818:Animals; D001921:Brain / Q000502:physiology; D001923:Brain Chemistry; D002940:Circadian Rhythm; D008297:Male; D011813:Quinuclidinyl Benzilate; D051381:Rats; D011919:Rats, Inbred Strains; D011976:Receptors, Muscarinic / Q000032:analysis*; D009435:Synaptic Transmission
chemical_list: D011976:Receptors, Muscarinic; D011813:Quinuclidinyl Benzilate; D000109:Acetylcholine