title: Acoustic analysis of voices of patients with neurologic disease: rationale and preliminary data.
abstract: This paper presents a rationale for acoustic analysis of voices of neurologically diseased patients, and reports preliminary data from patients with myotonic dystrophy, Huntington's disease, Parkinson's disease, and amyotrophic lateral sclerosis, as well as from individuals at risk for Huntington's disease. Noninvasive acoustic analysis may be of clinical value to the otolaryngologist, neurologist, and speech pathologist for early and differential diagnosis and for documenting disease progression in these various neurologic disorders.
authors.affiliation: Dept of Communication Disorders and Speech Science, University of Colorado, Boulder 80309.
authors.forename: L A
authors.initials: LA
authors.lastname: Ramig
authors.forename: R C
authors.initials: RC
authors.lastname: Scherer
authors.forename: I R
authors.initials: IR
authors.lastname: Titze
authors.forename: S P
authors.initials: SP
authors.lastname: Ringel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000690:Amyotrophic Lateral Sclerosis / Q000503:physiopathology; D005260:Female; D006801:Humans; D006816:Huntington Disease / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009223:Myotonic Dystrophy / Q000503:physiopathology; D009422:Nervous System Diseases / Q000175:diagnosis / Q000503:physiopathology*; D010300:Parkinson Disease / Q000503:physiopathology; D013060:Speech; D013061:Speech Acoustics; D014831:Voice; D014833:Voice Quality