Cerebral arterial constriction due to contrast media.
Angiography, either with Iohexol or Hexabrix, was carried out on a series of baboons, each of which had both contrast media, but on separate occasions. A double blind trial showed that in the carotid and middle cerebral arteries: Hexabrix generally caused vasoconstriction by 1.5 min, but in spite of a subsequent injection at 6 min constriction had largely disappeared by 20 minutes. Iohexol was generally followed by less severe constriction, but it may persist for longer and even show an increase at 20 min.
du Boulay
G H
GH
Institute of Neurology, National Hospital, London, England.
Wallis
A
A
D000792:Angiography / Q000009:adverse effects; D000818:Animals; D002343:Carotid Artery, Internal / Q000187:drug effects; D002536:Cerebral Arteries / Q000187:drug effects*; D007472:Iohexol / Q000633:toxicity*; D007485:Ioxaglic Acid / Q000633:toxicity*; D010215:Papio; D014661:Vasoconstriction / Q000187:drug effects*
D007472:Iohexol; D007485:Ioxaglic Acid