Symbioramide, a novel Ca2+-ATPase activator from the cultured dinoflagellate Symbiodinium sp.
A novel sphingosine derivative, symbioramide, has been isolated from the laboratory-cultured dinoflagellate Symbiodinium sp. as a sarcoplasmic reticulum (SR)Ca2+-ATPase activator, and its structure elucidated to be 1 on the basis of spectral and chemical means.
Kobayashi
J
J
Mitsubishi Kasei Institute of Life Sciences, Minamiooya, Machida, Tokyo 194, Japan.
Ishibashi
M
M
Nakamura
H
H
Hirata
Y
Y
Yamasu
T
T
Sasaki
T
T
Ohizumi
Y
Y
D000818:Animals; D000252:Calcium-Transporting ATPases / Q000378:metabolism*; D004141:Dinoflagellida / Q000032:analysis*; D004789:Enzyme Activation; D011817:Rabbits; D012519:Sarcoplasmic Reticulum / Q000201:enzymology; D013110:Sphingosine / Q000031:analogs & derivatives* / Q000302:isolation & purification / Q000494:pharmacology
C057218:symbioramide; D000252:Calcium-Transporting ATPases; D013110:Sphingosine