Affinity-purified varicella-zoster virus glycoprotein gp1/gp3 stimulates the production of neutralizing antibody.
Varicella-zoster virus glycoprotein gp1/gp3 was purified by affinity chromatography using anti-gp1/gp3 monoclonal antibody 19.1 linked to CNBr-activated Sepharose CL-4B. Rabbits immunized with purified glycoprotein gp1/gp3 developed mono-specific neutralizing antibody.
Wroblewska
Z
Z
Gilden
D
D
Green
M
M
Devlin
M
M
Vafai
A
A
D000818:Animals; D000917:Antibody Formation; D000936:Antigen-Antibody Complex; D002846:Chromatography, Affinity; D004591:Electrophoresis, Polyacrylamide Gel; D006023:Glycoproteins / Q000276:immunology* / Q000302:isolation & purification; D006562:Herpes Zoster / Q000382:microbiology; D014645:Herpesvirus 3, Human / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000302:isolation & purification; D051379:Mice; D011817:Rabbits / Q000276:immunology; D014764:Viral Proteins / Q000276:immunology* / Q000302:isolation & purification
D000936:Antigen-Antibody Complex; D006023:Glycoproteins; D007074:Immunoglobulin G; D014764:Viral Proteins