[The function of the neutrophil granulocyte in acne vulgaris].
Twenty seven patients with acne vulgaris were studied. Of them, 10 had minimal lesions and 17 had severe inflammatory lesions: nodulocystic, and conglobata. NBT and lysosomal neutrophil function was performed. The results shows a significative decreased values for the three test in patients with inflammatory lesions compared to patients with non-inflammatory lesions. The values for chemotactic function was 56.23 and 93%, for NBT test 50.82 and 93% and for lysosomal activity 60.88 and 88.9%, respectively. The authors proposed that the altered in vitro neutrophil function is a secondary phenomenon caused by specific and non-specific immunologic factors that occur in patients with severe inflammatory acne vulgaris.
Vignale
R
R
Facultad de Medicina, Hospital de Clínicas Doctor Manuel Quintela, Montevideo, Uruguay.
Lasalvia
E
E
Paciel
J
J
D000152:Acne Vulgaris / Q000503:physiopathology*; D000293:Adolescent; D000328:Adult; D002634:Chemotaxis, Leukocyte; D005260:Female; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000502:physiology*
Función del granulocito neutrófilo en el acné vulgar.