Influence of ACTH 4-10 and unilateral ECT on primary and secondary memory in depressive patients.
Primary and secondary memory were tested in depressive patients by means of immediate free recall of lists of words in a double blind intraindividual cross-over comparison between ACTH 4-10 in a single s.c. dose and placebo, in connection with the second and third unilateral electroconvulsive treatment (ECT). The results of the study did not show any memory facilitating effect of ACTH 4-10 in immediate recall from primary and secondary memory, after ECT. The results indicate a negative effect of ECT on delayed recall from secondary memory 120 min after ECT.
Frederiksen
S O
SO
d'Elia
G
G
Holsten
F
F
D000324:Adrenocorticotropic Hormone / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D003866:Depressive Disorder / Q000628:therapy*; D004311:Double-Blind Method; D004565:Electroconvulsive Therapy; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory / Q000187:drug effects*; D011939:Mental Recall / Q000187:drug effects*; D008875:Middle Aged; D010446:Peptide Fragments / Q000627:therapeutic use*; D012153:Retention, Psychology / Q000187:drug effects; D014706:Verbal Learning / Q000187:drug effects
D010446:Peptide Fragments; D000324:Adrenocorticotropic Hormone; C011394:ACTH (4-10)