Neurochemistry of dementia.
New neurotransmitter system abnormalities are being described in Alzheimer's disease, Parkinson's disease, and Huntington's disease at a rapid rate. Both classic and neuropeptide systems are affected in cortical and subcortical regions. Comprehensive understanding of the pathophysiology of these disorders will require understanding the multisystem nature and shared features of these disorders.
Whitehouse
P J
PJ
Alzheimer Center, University Hospital of Cleveland, Ohio.
Unnerstall
J R
JR
D001921:Brain / Q000378:metabolism*; D002540:Cerebral Cortex / Q000378:metabolism; D003704:Dementia / Q000378:metabolism*; D006624:Hippocampus / Q000378:metabolism; D006801:Humans; D006816:Huntington Disease / Q000378:metabolism; D010300:Parkinson Disease / Q000378:metabolism*