[Role of brain serotonin in the regulation of sexual maturation in male rats].
The effect of decrease of the brain serotonin level in different periods of prepubertal development on sexual maturation of male rats, was studied. Injections of p-CPA on the 30th and 34th days of life activated the endocrine function of testis in 60-day old animals. Injections of p-CPA later in life, on the 40th and 44th days, delayed sexual maturation as revealed by a decrease of spermatogenesis and endocrine function of testis. The data obtained suggest that serotonin has a dual role in regulation of the rate of sexual maturation in different periods of prepubertal age.
Shishkina
G T
GT
Borodin
P M
PM
D000818:Animals; D001921:Brain / Q000378:metabolism / Q000502:physiology*; D010134:Fenclonine / Q000494:pharmacology; D008297:Male; D009638:Norepinephrine / Q000378:metabolism; D051381:Rats; D012669:Seminal Vesicles / Q000187:drug effects; D012701:Serotonin / Q000378:metabolism / Q000502:physiology*; D012741:Sexual Maturation; D013094:Spermatozoa / Q000187:drug effects; D013737:Testis / Q000187:drug effects; D013739:Testosterone / Q000097:blood
D012701:Serotonin; D013739:Testosterone; D010134:Fenclonine; D009638:Norepinephrine
Uchastie serotonina golovnogo mozga v reguliatsii polovogo sozrevaniia samtsov krys.