Phenotypic diversity of the CD45 antigen and its relationship to function.
Monoclonal antibodies (mAbs) have identified further heterogeneity within the major CD4 and CD8 T-lymphocyte subsets. Antibodies to different polypeptides of the CD45 complex separate two largely non-overlapping subsets that may represent stages in the maturation of T cells or separate functionally distinct subsets.
Beverley
P C
PC
Human Tumour Immunology Group, University College Hospital Medical School, London, U.K.
Merkenschlager
M
M
Terry
L
L
D000818:Animals; D000943:Antigens, Differentiation / Q000032:analysis* / Q000276:immunology; D002460:Cell Line; D055598:Chemical Phenomena; D002621:Chemistry; D006649:Histocompatibility Antigens / Q000032:analysis* / Q000276:immunology; D006801:Humans; D017493:Leukocyte Common Antigens; D007962:Leukocytes / Q000276:immunology; D051379:Mice; D051381:Rats; D013601:T-Lymphocytes / Q000145:classification* / Q000276:immunology
D000943:Antigens, Differentiation; D006649:Histocompatibility Antigens; D017493:Leukocyte Common Antigens