NAN-190: an arylpiperazine analog that antagonizes the stimulus effects of the 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT).
Glennon
R A
RA
Department of Medicinal Chemistry, School of Pharmacy, Medical College of Virginia/Virginia Commonwealth University, Richmond 23298.
Naiman
N A
NA
Pierson
M E
ME
Titeler
M
M
Lyon
R A
RA
Weisberg
E
E
D017371:8-Hydroxy-2-(di-n-propylamino)tetralin; D000818:Animals; D003216:Conditioning, Operant / Q000187:drug effects; D004193:Discrimination Learning / Q000187:drug effects; D009281:Naphthalenes / Q000037:antagonists & inhibitors*; D010879:Piperazines / Q000494:pharmacology*; D011224:Prazosin / Q000494:pharmacology; D051381:Rats; D012702:Serotonin Antagonists; D013764:Tetrahydronaphthalenes / Q000037:antagonists & inhibitors*
D009281:Naphthalenes; D010879:Piperazines; D012702:Serotonin Antagonists; D013764:Tetrahydronaphthalenes; C058895:1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine; C018406:1-(3-trifluoromethylphenyl)piperazine; D017371:8-Hydroxy-2-(di-n-propylamino)tetralin; D011224:Prazosin