Human factor H (beta 1H-globulin): linkage analysis.
Linkage data on human factor H (HF) and 22 other human genetic markers are presented. Close linkage at theta less than 0.10 can be ruled out for a series of marker systems (Rh, PGM1, ACP1, Jk, Tf, Gc, MNSs, ME2, HLA, GLO1, ORM, Gt, PI, Hp, GPT). Strong evidence for linkage was obtained for peptidase A (PEPA) with lods greater than 3.0 at theta = 0.10 in males and at theta = 0.20 for the sexes combined. From this result the HF locus can be provisionally assigned to chromosome 18.
Kömpf
J
J
Institut für Anthropologie und Humangenetik der Universität, Tübingen, Federal Republic of Germany.
Luckenbach
C
C
Kloor
D
D
Schunter
F
F
Wernet
P
P
Ritter
H
H
D003180:Complement C3b Inactivator Proteins / Q000235:genetics*; D017242:Complement Factor H; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans
C493495:CFH protein, human; D003180:Complement C3b Inactivator Proteins; D005819:Genetic Markers; D017242:Complement Factor H