[Comparative evaluation of the accumulation of 99mTc-labeled phosphate compounds in the bones].
Distribution of osteotropic radiopharmaceuticals was studied in bone, different organs and tissues of rats. 99mTc-pyrophosphate (USSR and France) and 99mTc-diphosphonate (GDR and Hungary) were investigated. Differences in their behaviour were demonstrated. According to a degree of accumulation in the bone tissue, the preparations may be arranged as follows: 99mTc-diphosphonate (GDR), 99mTc-diphosphonate (Hungary), 99mTc-pyrophosphate (USSR and France).
Atamaniuk
N P
NP
Mechev
D S
DS
D000818:Animals; D001842:Bone and Bones / Q000378:metabolism*; D011756:Diphosphates / Q000378:metabolism*; D004164:Diphosphonates / Q000378:metabolism*; D005602:France; D005859:Germany, East; D006814:Hungary; D051381:Rats; D013667:Technetium / Q000378:metabolism*; D017556:Technetium Compounds; D016698:Technetium Tc 99m Pyrophosphate; D013997:Time Factors; D014018:Tissue Distribution; D014586:USSR
D011756:Diphosphates; D004164:Diphosphonates; D017556:Technetium Compounds; D016698:Technetium Tc 99m Pyrophosphate; D013667:Technetium; C029045:technetium Tc 99m diphosphonate
Sravnitel'naia otsenka nakopleniia v kostiakh fosfatnykh soedineniĭ, mechennykh 99mTc.