title: [Biological effects of leakadin].
abstract: 57 patients with disseminated tumors of various sites received 10 daily doses of 600 mg/m2 leakadin intravenously. The immunostimulating effect was observed (OKT4/OKT8 normalization). The data on leakadin pharmacokinetics are discussed.
authors.forename: A M
authors.initials: AM
authors.lastname: Garin
authors.forename: M R
authors.initials: MR
authors.lastname: Lichinitser
authors.forename: N V
authors.initials: NV
authors.lastname: Dmitrieva
authors.forename: B I
authors.initials: BI
authors.lastname: Rubtsov
authors.forename: N V
authors.initials: NV
authors.lastname: Leneva
mesh_terms: D000276:Adjuvants, Immunologic / Q000493:pharmacokinetics / Q000627:therapeutic use*; D000328:Adult; D000818:Animals; D000970:Antineoplastic Agents / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001388:Aziridines / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001389:Azirines / Q000627:therapeutic use*; D006801:Humans; D007694:Killer Cells, Natural; D007958:Leukocyte Count; D051379:Mice; D008875:Middle Aged; D009369:Neoplasms / Q000097:blood / Q000188:drug therapy*; D009374:Neoplasms, Experimental / Q000097:blood / Q000188:drug therapy*; D050378:T-Lymphocytes, Regulatory
chemical_list: D000276:Adjuvants, Immunologic; D000970:Antineoplastic Agents; D001388:Aziridines; D001389:Azirines; C055240:Leakadine
vernacular_title: Biologicheskie éffekty leakadina.