A comparison of energy metabolism and the effects of beta-adrenergic stimulation in the tongue and attached gingiva of the dog.
Glucose-6-phosphate (G6P), ATP, phosphorylcreatine (CP) and lactate were assayed in the tongue attached gingiva of dogs. The G6P content was found to be significantly higher, and both the ATP and CP contents even more significantly higher in the tongue than in the attached gingiva. Lactate content was not significantly different in the gingiva and in the tongue. The changes in the concentrations of G6P, ATP, CP and lactate due to the intravenous infusion of isoproterenol hydrochloride (1 micrograms/kg/min) were as follows. In the tongue, G6P exhibited a significant increase, but the decrease in ATP and CP contents as well as the increase in lactate content were not significant. It is possible that these effects were the result of the activation of beta-adrenergic receptors by isoproterenol. In the attached gingiva, there was no significant change in the G6P, ATP, or CP content. Lactate increased to a greater degree than the other three components, but similarly did not reach the significant level.
Robin
O
O
Andrieu
J L
JL
Faucon
G
G
Timour Chah
Q
Q
D000255:Adenosine Triphosphate / Q000032:analysis; D000818:Animals; D004285:Dogs; D004734:Energy Metabolism; D005881:Gingiva / Q000378:metabolism*; D019298:Glucose-6-Phosphate; D005958:Glucosephosphates / Q000032:analysis; D007545:Isoproterenol / Q000494:pharmacology; D007773:Lactates / Q000032:analysis; D019344:Lactic Acid; D010725:Phosphocreatine / Q000032:analysis; D011943:Receptors, Adrenergic, beta / Q000187:drug effects / Q000378:metabolism*; D014059:Tongue / Q000378:metabolism*
D005958:Glucosephosphates; D007773:Lactates; D011943:Receptors, Adrenergic, beta; D010725:Phosphocreatine; D019344:Lactic Acid; D019298:Glucose-6-Phosphate; D000255:Adenosine Triphosphate; D007545:Isoproterenol