title: [Biopsy of the chorionic villi in the early diagnosis of chromosomal diseases].
abstract: In the first trimester of pregnancy two simple chorionic villus sampling method, carried out under ultrasound guidance, with transabdominal or transcervical aspiration, was evaluated in 257 cases at risk for chromosomic diseases. The high efficacy of the transabdominal aspiration was demonstrated by obtain villus tissue for karyotyping in all but one case. In only one sample the abnormalities detected were not confirmed (one case of false positive).
authors.affiliation: Istituto di Clinica Ostetrica e Ginecologica dell'Università di Parma.
authors.forename: V
authors.initials: V
authors.lastname: Calestani
authors.forename: F
authors.initials: F
authors.lastname: Taddei
authors.forename: A
authors.initials: A
authors.lastname: Venturini
authors.forename: S
authors.initials: S
authors.lastname: Raboni
authors.forename: D
authors.initials: D
authors.lastname: Fiaschetti
authors.forename: F
authors.initials: F
authors.lastname: Chiavazza
mesh_terms: D015193:Chorionic Villi Sampling / Q000379:methods; D002869:Chromosome Aberrations / Q000175:diagnosis*; D025063:Chromosome Disorders; D005260:Female; D005865:Gestational Age; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy; D014463:Ultrasonography
vernacular_title: La biopsia dei villi coriali nella diagnosi precoce di malattie cromosomiche.