The human immunodeficiency virus and its pathogenesis.
HIV is a lentivirus that infects many tissues of the body, including the cells of the brain, the hematopoietic system, and the bowel epithelium. Its spread is mediated by virus-infected cells. Control of HIV depends on a strong host immune response against virus-infected cells, either through suppression of virus release or through killing of the virus-infected cells. Present studies are directed at understanding mechanisms by which effective antiviral therapy and a vaccine can be developed.
Levy
J A
JA
Department of Medicine, University of California, San Francisco.
D001323:Autoantibodies / Q000032:analysis; D006678:HIV / Q000145:classification / Q000276:immunology / Q000472:pathogenicity*; D006801:Humans; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology / Q000382:microbiology
D001323:Autoantibodies