title: Phase 1 and 2 studies of trimetrexate administered in combination with fluorouracil to patients with metastatic cancer.
authors.affiliation: Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111.
authors.forename: G R
authors.initials: GR
authors.lastname: Hudes
authors.forename: R L
authors.initials: RL
authors.lastname: Comis
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D004341:Drug Evaluation; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000188:drug therapy*; D011799:Quinazolines / Q000008:administration & dosage*; D016597:Trimetrexate
chemical_list: D011799:Quinazolines; D005472:Fluorouracil; D016597:Trimetrexate