Nucleotide sequence of the AIDS virus, LAV.
The complete 9193-nucleotide sequence of the probable causative agent of AIDS, lymphadenopathy-associated virus (LAV), has been determined. The deduced genetic structure is unique: it shows, in addition to the retroviral gag, pol, and env genes, two novel open reading frames we call Q and F. Remarkably, Q is located between pol and env and F is half-encoded by the U3 element of the LTR. These data place LAV apart from the previously characterized family of human T cell leukemia/lymphoma viruses.
Wain-Hobson
S
S
Sonigo
P
P
Danos
O
O
Cole
S
S
Alizon
M
M
D000163:Acquired Immunodeficiency Syndrome / Q000382:microbiology*; D000595:Amino Acid Sequence; D000956:Antigens, Viral / Q000235:genetics; D001483:Base Sequence; D003001:Cloning, Molecular; D004279:DNA, Viral / Q000235:genetics*; D017977:Deltaretrovirus / Q000235:genetics*; D015683:Gene Products, gag; D005796:Genes; D005814:Genes, Viral; D006801:Humans; D013045:Species Specificity; D014759:Viral Envelope Proteins / Q000235:genetics; D014764:Viral Proteins / Q000235:genetics*
D000956:Antigens, Viral; D004279:DNA, Viral; D015683:Gene Products, gag; D014759:Viral Envelope Proteins; D014764:Viral Proteins