[Management in cases of accidental contamination by iodine radioisotopes].
Iodide can reduce radioactive iodine thyroid uptake and whole-body irradiation. Maximal effectiveness is obtained when 3 conditions are fulfilled: adequate dosage: potassium iodide 130 mg (i.e. iodide 100 mg) as tablets in adults and older children, 50 mg in infants under one year of age; prompt administration after contamination and daily treatment as long as the contamination persists. Depending on the importance and duration of the contamination, different dosages may be required. In any case, children must be given priority for prophylactic measures.
Schlumberger
M
M
Institut Gustave-Roussy, Villejuif.
Parmentier
N
N
Chavaudra
J
J
Parmentier
C
C
Tubiana
M
M
D000059:Accidents; D000293:Adolescent; D000328:Adult; D002648:Child; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007454:Iodides / Q000009:adverse effects / Q000627:therapeutic use*; D007457:Iodine Radioisotopes / Q000009:adverse effects*; D009688:Nuclear Reactors; D011044:Poland; D011877:Radionuclide Imaging; D013959:Thyroid Diseases / Q000139:chemically induced; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy; D014455:Ukraine
D007454:Iodides; D007457:Iodine Radioisotopes
Conduite à tenir en cas de contamination accidentelle par les radioisotopes de l'iode.