Re-evaluation of "frontal deafferentation" studies on the regulation of ACTH secretion in the light of CRF immunohistology.
Frontal afferents to the medial basal hypothalamus of the rat were interrupted by a Halász knife, and 4 weeks later the brains were processed for immunostaining of CRF-fibers. It was found that such intervention saves most of the CRF immunoreactive fibers of the paraventriculo-infundibular tract. Some of the conflicting results of earlier deafferentation studies are discussed on the basis of CRF immunohistology.
Lengvári
I
I
Liposits
Z
Z
Vigh
S
S
Schally
A V
AV
Flerkó
B
B
D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D000818:Animals; D001923:Brain Chemistry; D003346:Corticotropin-Releasing Hormone / Q000032:analysis*; D006651:Histocytochemistry; D007033:Hypothalamus, Middle / Q000502:physiology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D000324:Adrenocorticotropic Hormone; D003346:Corticotropin-Releasing Hormone