Summary of the toxicologic profile of iopentol.
Repeat dose toxicity studies, reproductive studies and mutagenicity studies were performed to assess the safety of iopentol. It is concluded that iopentol, a non-ionic contrast medium, is free from significant toxic effects.
Heywood
R
R
Huntingdon Research Centre Plc., Cambs., England.
Mayfield
R
R
Allan
J A
JA
Michelet
A A
AA
D000014:Abnormalities, Drug-Induced / Q000209:etiology; D000818:Animals; D003287:Contrast Media / Q000633:toxicity*; D005260:Female; D008252:Macaca fascicularis; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012098:Reproduction / Q000187:drug effects; D014283:Triiodobenzoic Acids / Q000633:toxicity*
D003287:Contrast Media; D014283:Triiodobenzoic Acids; C053571:iopentol