title: Increased serum IgG4 levels in acute Epstein-Barr viral mononucleosis.
abstract: Changes in serum IgG4 levels during heterophil-positive infectious mononucleosis were recorded. Pre-illness serial acute and convalescent specimens were evaluated. Mean IgG4 levels increased by 75% during acute infectious mononucleosis, reached a peak 21/2 to 3 weeks post-onset, and declined to baseline by 60 days. IgG4 peaked independently of other immunoglobulin classes.
authors.forename: S J
authors.initials: SJ
authors.lastname: Shacks
authors.forename: D C
authors.initials: DC
authors.lastname: Heiner
authors.forename: S L
authors.initials: SL
authors.lastname: Bahna
authors.forename: C A
authors.initials: CA
authors.lastname: Horwitz
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D000917:Antibody Formation; D005260:Female; D004854:Herpesvirus 4, Human; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007244:Infectious Mononucleosis / Q000276:immunology*; D008297:Male; D013997:Time Factors
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G