[Importance of antibiotic combinations with ceftazidime and usefulness in the prevention of resistance].
Different antibiotics can be used in combinations to extend the antibacterial spectrum, to obtain a synergistic bactericidal effect or to prevent bacterial resistance. Ceftazidime may be combined with other antibiotic to extend its spectrum to Staphylococci and Enterococci, or even anaerobes. A synergistic effect is mainly obtained with aminoglycosides. To prevent the emergence of resistant strains, ceftazidime may be combined with aminoglycosides and the new quinolones.
Gutmann
L
L
Service de Microbiologie médicale, Hôpital Saint-Joseph, Paris.
Blériot
J P
JP
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002442:Ceftazidime / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D006090:Gram-Negative Bacteria / Q000187:drug effects
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D002442:Ceftazidime
Intérêt des associations d'antibiotiques avec la ceftazidime et utilité dans la prévention de la résistance.