Primary malignant fibrous histiocytoma of the uterus--ultrastructural and immunocytochemical studies of two cases.
The clinical and pathological features, including ultrastructural and immunocytochemical findings, of 2 cases of primary malignant fibrous histiocytoma of the uterus are reported. One patient had pulmonary metastases at the time of hysterectomy: she developed pelvic recurrence and died 3 mth after operation. The other patient was well and apparently free of disease 6 mth after hysterectomy. Histologically both tumours resembled pleomorphic leiomyosarcoma, and the diagnosis of a malignant fibrous histiocytoma was confirmed only after electron microscopic and immunocytochemical studies. Hormone receptor assay for estrogen and progesterone was positive in both tumours. Anti-estrogen treatment was started in one case but was ineffective.
Chou
S T
ST
Fortune
D
D
Beischer
N A
NA
McLeish
G
G
Castles
L A
LA
McKelvie
B A
BA
Planner
R S
RS
D000368:Aged; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007124:Immunoenzyme Techniques; D008875:Middle Aged; D014594:Uterine Neoplasms / Q000473:pathology* / Q000648:ultrastructure