Variation in response to CCNU of glioblastoma multiforme in brain and cervical lymph node. Case report.
The case is reported of a patient in whom a cervical lymph node metastasis decreased in size while the primary intracranial glioblastoma continued to grow during chemotherapy with CCNU (1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea). This is the first such case reported in humans. Possible explanations for this phenomenon are discussed.
Steinbok
P
P
Dolman
C L
CL
Goldie
J H
JH
D000328:Adult; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D005909:Glioblastoma / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008130:Lomustine / Q000627:therapeutic use*; D008207:Lymphatic Metastasis / Q000188:drug therapy* / Q000473:pathology
D008130:Lomustine