[Effect of tuftsin, a neuropeptide and its derivatives on the content of nicotinamide coenzymes and the activity of cytochrome- c-oxidase of brain tissue].
Tuftsin, a neuropeptide, and its derivatives are studied for their influence on the content of oxidized and reduced forms of nicotinamide enzymes as well as on the activity of cytochrome-c-oxidase of the cortex and limbic system. Peptides under study are shown to increase the content of nicotinamide coenzymes, mainly due to the oxidized forms of NAD and enhance the activity of cytochrome-c-oxidase as well mainly in the emotiogenic brain structures. Under these conditions tuftsin and its derivatives intensify cellular respiration of the neurons.
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D000818:Animals; D001921:Brain / Q000201:enzymology*; D003576:Electron Transport Complex IV / Q000378:metabolism*; D009243:NAD / Q000378:metabolism*; D009249:NADP / Q000378:metabolism*; D051381:Rats; D013268:Stimulation, Chemical; D014405:Tuftsin / Q000008:administration & dosage / Q000494:pharmacology*
D009243:NAD; D009249:NADP; D003576:Electron Transport Complex IV; D014405:Tuftsin
Vliianie neĭropeptida taftsina i ego proizvodnykh na soderzhanie nikotinamidnykh kofermentov i aktivnost' tsitokhrom-c-oksidazy tkaneĭ golovnogo mozga.