[Age-related differences in the inhibition of DNA synthesis in the liver of albino rats by proliferation inhibitors of chalone type].
It was demonstrated that during postnatal ontogenesis, the heterogeneity of endogenous inhibitors of DNA synthesis in albino rat liver does not change. Upon ageing, the sensitivity of liver cells to the inhibiting effect of chalone-containing extracts and the functional activity of the inhibitor are diminished.
Klimenko
A I
AI
Shevtsova
M Ia
MIa
Malyshev
A B
AB
Gautsel'
V V
VV
D000375:Aging / Q000378:metabolism*; D000818:Animals; D002455:Cell Division / Q000187:drug effects; D004247:DNA / Q000096:biosynthesis*; D006131:Growth Inhibitors / Q000494:pharmacology*; D008099:Liver / Q000378:metabolism*; D008115:Liver Regeneration; D051381:Rats; D011919:Rats, Inbred Strains
D006131:Growth Inhibitors; D004247:DNA
Vozrastnye razlichiia podavleniia sinteza DNK v pecheni belykh krys ingibitorami proliferatsii keĭlonovoĭ prorody.