The occurrence of metals Al, Fe, Ni, Cu, Zn in the nuclei of animal cells: an ultrastructural, in situ, X-ray microanalytical study.
Cell nuclei may contain significant quantities of the metals Fe, Ni, Cu, Zn, since they are present in the nucleo-enzymes and/or nucleic acids. These metals have been detected by X-ray microanalysis in situ in dinoflagellates (Kearns et al). Aluminum was only detected in cell nuclei in cases of natural or provoked intoxication. We observed at the ultrastructural level, in situ, the presence of Al, Fe, Ni, Cu, Zn in nuclei of different types of non-intoxicated animal cells. Moreover, we measured the concentration of these metals in the nucleolus and chromatin and compared it with the concentration of P and S.
Quintana
C
C
Unité de Recherche 194 INSERM, 91, Paris, France.
Olmedilla
A
A
Antoine
N
N
Ollacarizqueta
A
A
D000535:Aluminum / Q000032:analysis*; D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure*; D003300:Copper / Q000032:analysis*; D004577:Electron Probe Microanalysis; D005260:Female; D007501:Iron / Q000032:analysis*; D008854:Microscopy, Electron; D009532:Nickel / Q000032:analysis*; D006080:Ovarian Follicle / Q000648:ultrastructure; D010053:Ovary / Q000648:ultrastructure; D010057:Oviducts / Q000648:ultrastructure; D011784:Quail; D051381:Rats; D011919:Rats, Inbred Strains; D015032:Zinc / Q000032:analysis*
D003300:Copper; D009532:Nickel; D000535:Aluminum; D007501:Iron; D015032:Zinc