[Bronchoalveolar lavage in patients with sarcoidosis--methodologic aspects of the collection, immunologic characterization of lymphocytes and studies of immunoglobulin content].
The activity of alveolitis in 25 patients with pulmonary sarcoidosis was determined by analysis of T-Lymphocytes and their subpopulations collected by broncho-alveolar lavage. The characterization of the lymphocytes was performed with monoclonal antibodies (BL-series). An amount of T-lymphocytes higher than 28% of all cells and a proportion of T4/T8-lymphocytes of 8:1 and over are signs of the activity of the alveolitis and an indication for corticoid therapy.
Ballin
A
A
Robert-Koch-Klinik, Bezirkskrankenhaus für Lungenkrankheiten Leipzig, DDR.
Bigl
H
H
Ferner
S
S
Fiebig
H
H
Leonhardt
P
P
Neubert
R
R
Cebulla
M
M
D000911:Antibodies, Monoclonal; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology*; D006801:Humans; D007136:Immunoglobulins / Q000378:metabolism*; D007958:Leukocyte Count; D008171:Lung Diseases / Q000276:immunology*; D012507:Sarcoidosis / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
D000911:Antibodies, Monoclonal; D007136:Immunoglobulins
Broncho-alveoläre Lavage bei Sarkoidosepatienten--Methodische Aspekte der Gewinnung, immunologische Charakterisierung von Lymphozyten und Untersuchungen zum Immunglobulingehalt.