Effect of exhaustive exercise on liver mitochondrial function in the rat.
The oxidative and phosphorylative function of rat liver mitochondria after exhaustive exercise was investigated. The stimulation of state 4 respiration (without ADP) with NADH and FADH2 dependent substrates was demonstrated. The reduction in RCR ratio (the rate of oxidation in state 3/the rate of oxidation in state 4) and enhanced activity of oligomycin sensitive ATP-ase was also found. The results suggest an inhibition of liver mitochondrial phosphorylative activity in rats exercised till exhaustion.
Bielecki
J W
JW
Department of Physiology, School of Medicine, Białystok.
Pawlicka
E
E
Górski
J
J
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D004734:Energy Metabolism; D005221:Fatigue / Q000378:metabolism*; D008297:Male; D008930:Mitochondria, Liver / Q000378:metabolism*; D010085:Oxidative Phosphorylation; D010101:Oxygen Consumption; D005082:Physical Exertion; D051381:Rats; D011919:Rats, Inbred Strains
D000251:Adenosine Triphosphatases