title: Sustained improvement in myocardial perfusion four to six years after PTCA in patients with a satisfactory angiographic result, six months after the procedure.
abstract: Of 46 consecutive patients who underwent percutaneous transluminal coronary angioplasty (PTCA) from April 1980 to August 1982 and who had a satisfactory angiographic result six months later, one died of cancer and 41 had a detailed evaluation with exercise single-photon emission computed tomography (SPECT, 40 patients) or repeat coronary angiography (one patient), 48-78 months after the procedure. During follow-up, two patients had recurrent angina due to progression of coronary artery disease requiring a second PTCA procedure of another coronary artery; one of them later had a limited myocardial infarction in an area supplied by the vessel initially dilated. At follow-up, only one patient had definite angina. All but one patient had a negative exercise test. Myocardial perfusion during exercise in the PTCA-related area, assessed by SPECT, was normal in 90% of the patients and showed a limited defect due to reversible ischaemia in the remaining four (10%). It is concluded that patients with a less than 50% stenosis six months after PTCA show sustained improvement in their functional status and myocardial perfusion, four to six years after the procedure suggesting continued patency of the coronary artery.
authors.affiliation: Department of Cardiology, CHU Nancy-Brabois, Vandoeuvre-lès-Nancy, France.
authors.forename: N
authors.initials: N
authors.lastname: Danchin
authors.forename: A
authors.initials: A
authors.lastname: Haouzi
authors.forename: M
authors.initials: M
authors.lastname: Amor
authors.forename: G
authors.initials: G
authors.lastname: Karcher
authors.forename: F
authors.initials: F
authors.lastname: Brunotte
authors.forename: Y
authors.initials: Y
authors.lastname: Juilliere
authors.forename: M
authors.initials: M
authors.lastname: Cuilliere
authors.forename: J P
authors.initials: JP
authors.lastname: Villemot
authors.forename: C
authors.initials: C
authors.lastname: Pernot
authors.forename: J M
authors.initials: JM
authors.lastname: Gilgenkrantz
mesh_terms: D000328:Adult; D000368:Aged; D000789:Angina, Unstable / Q000628:therapy; D000800:Angioplasty, Balloon / Q000401:mortality*; D003326:Coronary Circulation; D005260:Female; D005500:Follow-Up Studies; D006321:Heart / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D005082:Physical Exertion; D011877:Radionuclide Imaging; D013794:Thallium Radioisotopes; D013997:Time Factors
chemical_list: D013794:Thallium Radioisotopes