title: [Allergic contact dermatitis to prednisolone-21-trimethyl acetate].
abstract: A 64-year-old female patient developed periorbital eczema after eye treatment with a corticoid ointment. Epicutaneous tests with the effective component as well as with other ingredients of the ointment and suspected substances revealed a delayed hypersensitivity to prednisolone-21-trimethyl acetate, neomycin, cobalt, and cetyl alcohol. We did not observe any cross-reactions to other corticoids, not even to the closely related prednisolone-21-monoacetate. To the best of our knowledge, allergic contact dermatitis to prednisolone-21-trimethyl acetate has not been described in the literature so far.
authors.affiliation: Universitäts-Hautklinik Hamburg.
authors.forename: M
authors.initials: M
authors.lastname: Schmoll
authors.forename: B M
authors.initials: BM
authors.lastname: Hausen
mesh_terms: D001762:Blepharitis / Q000139:chemically induced*; D003875:Drug Eruptions / Q000209:etiology*; D005141:Eyelid Diseases / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010328:Patch Tests; D011239:Prednisolone / Q000009:adverse effects / Q000031:analogs & derivatives*
chemical_list: C002442:mecortolon; D011239:Prednisolone
vernacular_title: Allergische Kontaktdermatitis auf Prednisolon-21-trimethylacetat.