[Autonomic cardiovascular regulation and permanent catheterization in normotensive conscious (WKY) and spontaneously hypertensive (SHR) rats].
In cardiovascular research, methods of indwelling catheterism have been frequently described. In the present work, we used normotensive and SHR rats to compare carotid catheterism to left ventricular catheterism, this last method being proposed by some investigators for cardiac index measurement. Our results of plasma catecholamines and autonomous nervous system activity show that ventricular catheterism results in an important disturb in cardiovascular regulation and question its validity to study cardiac function.
Midol-Monnet
M
M
Laboratoire de Pharmacologie, U.A.-C.N.R.S. 594, Faculté de Pharmacie, Châtenay-Malabry.
Heimburger
M
M
Davy
M
M
Beslot
F
F
Cohen
Y
Y
D000109:Acetylcholine / Q000008:administration & dosage; D000818:Animals; D001794:Blood Pressure; D006328:Cardiac Catheterization / Q000009:adverse effects*; D002319:Cardiovascular System / Q000503:physiopathology*; D002395:Catecholamines / Q000097:blood; D002408:Catheters, Indwelling / Q000009:adverse effects; D006339:Heart Rate; D007545:Isoproterenol / Q000008:administration & dosage; D008297:Male; D009638:Norepinephrine / Q000008:administration & dosage; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY
D002395:Catecholamines; D007545:Isoproterenol; D000109:Acetylcholine; D009638:Norepinephrine
Régulation cardiovasculaire autonome et cathétérisme permanent chez le rat éveillé normotendu (WKY) et spontanément hypertendu (SHR).