title: [Severe psoriasis induced by chloroquine (nivaquine)].
abstract: The adverse effects of a variety of drugs on psoriasis are well documented, and they generally result in aggravation of the disease. We report the case of a 75-year old man who developed a psoriatic erythroderma and a generalized pustular psoriasis two weeks after the beginning of an antimalarial treatment. The psoriasis responded poorly to etretinate alone, and an etretinate-methotrexate combination was needed to cure the patient. Some psoriasis vulgaris plaques persisted for six months after the acute complication. Thus, chloroquine should be entered in the list of drugs which may induce psoriasis.
authors.affiliation: Clinique Dermatologique, Hôpital E. Herriot, Lyon.
authors.forename: J F
authors.initials: JF
authors.lastname: Nicolas
authors.forename: G
authors.initials: G
authors.lastname: Mauduit
authors.forename: J
authors.initials: J
authors.lastname: Haond
authors.forename: B
authors.initials: B
authors.lastname: Chouvet
authors.forename: J
authors.initials: J
authors.lastname: Thivolet
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002738:Chloroquine / Q000009:adverse effects*; D003873:Dermatitis, Exfoliative / Q000139:chemically induced* / Q000473:pathology; D003875:Drug Eruptions / Q000209:etiology*; D004347:Drug Interactions; D006801:Humans; D008297:Male; D011565:Psoriasis / Q000139:chemically induced* / Q000473:pathology
chemical_list: D002738:Chloroquine
vernacular_title: Psoriasis grave induit par la chloroquine (nivaquine).