An 18-year history of a corticotropin-secreting spindle cell carcinoid in the lung.
A unique case is reported demonstrating latency and slow growth of a spindle-cell carcinoid in the lung. Seventeen years after bilateral adrenalectomy, performed for Cushing's syndrome, a patient presented with a newly developed lung tumor. The tumor demonstrated spindle cell histology, neurosecretory granules typical for carcinoid, and a positive immunoreactivity for corticotropin. After the removal of the lung tumor, the high serum corticotropin level returned to normal.
Yamashina
M
M
D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D002294:Carcinoma, Squamous Cell / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000378:metabolism* / Q000473:pathology; D008875:Middle Aged; D013997:Time Factors
D000324:Adrenocorticotropic Hormone