title: GNRH induces activation of Leydig-like cells in Pleurodeles waltlii. A morphometric study.
abstract: The ultrastructure of the interstitial cells of the glandular tissue of Pleurodeles waltlii was studied in testis of animals obtained in early breeding season (January) under gonadotropic releasing hormone (GNRH) treatments and controls. These cells (parenchymal or Leydig-like cells) displayed the structural characteristics of steroid-producing cells. GNRH administration for 24 hours induced a significant decrease of both medial volume and volume density of lipid droplets. On the other hand, cell volume, nucleus, mitochondria, mitochondrial cristae and tubules of smooth endoplasmic reticulum were increased. The surface density of mitochondrial cristae was also increased.
authors.affiliation: Department of Cell Biology, University of Córdoba, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Moya
authors.forename: F
authors.initials: F
authors.lastname: Guerrero
authors.forename: P
authors.initials: P
authors.lastname: Navas
authors.forename: G
authors.initials: G
authors.lastname: García-Herdugo
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000187:drug effects / Q000648:ultrastructure; D004721:Endoplasmic Reticulum / Q000187:drug effects / Q000648:ultrastructure; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology*; D007985:Leydig Cells / Q000187:drug effects* / Q000648:ultrastructure; D008297:Male; D008928:Mitochondria / Q000187:drug effects / Q000648:ultrastructure; D015388:Organelles / Q000187:drug effects* / Q000648:ultrastructure; D010999:Pleurodeles; D012016:Reference Values
chemical_list: D007987:Gonadotropin-Releasing Hormone