A sequence downstream of A-A-U-A-A-A is required for formation of simian virus 40 late mRNA 3' termini in frog oocytes.
The 3' terminus of simian virus 40 late mRNA is formed by nucleolytic cleavage of an mRNA precursor. In this report we show that efficient cleavage requires a sequence in the 3' flanking region, "downstream" of the highly conserved A-A-U-A-A-A sequence. This sequence is not required for polyadenylylation itself or for accurately positioning the 3' terminus that is formed.
Conway
L
L
Wickens
M
M
D000818:Animals; D001483:Base Sequence; D002872:Chromosome Deletion; D005260:Female; D005796:Genes; D005809:Genes, Regulator; D009865:Oocytes; D011061:Poly A / Q000235:genetics*; D012323:RNA Processing, Post-Transcriptional; D012333:RNA, Messenger / Q000235:genetics*; D012367:RNA, Viral / Q000235:genetics; D013539:Simian virus 40 / Q000235:genetics; D014982:Xenopus laevis
D012333:RNA, Messenger; D012367:RNA, Viral; D011061:Poly A