title: Magnitude of ouabain-sensitive respiration of lamb hepatocytes (Ovis aries).
abstract: In lamb hepatocyte preparations with viabilities greater than 90%, ouabain-sensitive respiration accounted for approximately 50% of the total cellular O2 consumption. Lamb hepatocyte preparations with viability of less than 50% exhibited lower (P less than 0.05) total and ouabain-sensitive respiration. The decrease in ouabain-sensitive respiration in these preparations entirely accounted for the drop in total respiration.
authors.forename: B W
authors.initials: BW
authors.lastname: McBride
authors.forename: L P
authors.initials: LP
authors.lastname: Milligan
mesh_terms: D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D002470:Cell Survival; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D010042:Ouabain / Q000494:pharmacology*; D010101:Oxygen Consumption / Q000187:drug effects*; D012756:Sheep / Q000378:metabolism*; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors / Q000378:metabolism*
chemical_list: D010042:Ouabain; D000254:Sodium-Potassium-Exchanging ATPase