Reversible, late-onset disulfiram-induced neuropathy and encephalopathy.
Disulfiram toxicity is a well-recognized cause of peripheral neuropathy and encephalopathy, usually developing within a few months of the start of therapy. We describe a patient who insidiously developed a peripheral neuropathy and encephalopathy after thirty years of disulfiram ingestion. Both complications partially resolved after the medication was stopped.
Borrett
D
D
Ashby
P
P
Bilbao
J
J
Carlen
P
P
D000368:Aged; D001706:Biopsy; D001927:Brain Diseases / Q000139:chemically induced*; D004221:Disulfiram / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000473:pathology; D013497:Sural Nerve / Q000473:pathology; D013997:Time Factors
D004221:Disulfiram