Pneumatosis intestinalis in patients after cadaveric kidney transplantation: possible relationship with an active cytomegalovirus infection.
Four patients are presented with pneumatosis intestinalis following kidney transplantation, all with severe cytomegalovirus (CMV) infection. Two patients had a primary infection and two patients had CMV reactivation. One patient died because of disseminated CMV infection. Two patients had concomitantly an active, non-obstructive duodenal ulcer. In a control population of 17 patients who suffered from a duodenal ulcer post-transplant without any evidence of CMV infection, we could not demonstrate pneumatosis intestinalis. We suggest a possible relationship between pneumatosis intestinalis and active CMV infection. The possible mechanisms responsible for this relationship are discussed.
van Son
W J
WJ
van der Woude
F J
FJ
van der Jagt
E J
EJ
Donker
A J
AJ
Meijer
S
S
Slooff
M J
MJ
The
T H
TH
Tegzess
A M
AM
van der Slikke
L B
LB
D000328:Adult; D003586:Cytomegalovirus Infections / Q000150:complications*; D004381:Duodenal Ulcer / Q000150:complications; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011006:Pneumatosis Cystoides Intestinalis / Q000209:etiology*