title: Small bowel cancers, B-cell lymphatic leukemia, and six primary cancers with metastases and prolonged survival in the cancer family syndrome of Lynch.
abstract: The Cancer Family Syndrome of Lynch (CFS) is characterized by the frequent occurrence of multiple types of cancers, often adenocarcinomas of the colon, endometrium, and breast, at early ages in a pedigree pattern suggesting an autosomal dominant mechanism of inheritance. An unusual CFS pedigree is presented in which members exhibited rare cancers, six primary cancers, and prolonged survival.
authors.forename: R R
authors.initials: RR
authors.lastname: Love
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics / Q000556:secondary; D002288:Adenocarcinoma, Mucinous / Q000235:genetics; D000328:Adult; D001402:B-Lymphocytes; D001943:Breast Neoplasms / Q000235:genetics; D002051:Burkitt Lymphoma / Q000235:genetics / Q000401:mortality; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000235:genetics; D003536:Cystadenocarcinoma / Q000235:genetics; D005260:Female; D005833:Genital Neoplasms, Female / Q000235:genetics; D006801:Humans; D007414:Intestinal Neoplasms / Q000235:genetics*; D007417:Intestinal Polyps / Q000235:genetics; D007938:Leukemia / Q000235:genetics*; D008113:Liver Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000235:genetics*; D010375:Pedigree; D011379:Prognosis; D013577:Syndrome