title: Antiviral activity of coumermycin: identification of resistant and sensitive retrovirus strains.
abstract: The effect of Coumermycin (CA1) on the replication of different ecotropic retroviruses was studied. Most strains showed reductions in infectivity of less than ten fold, while two strains demonstrated a marked sensitivity to the drug. The isolation of one resistant strain could suggest a specific CA1 antiviral activity.
authors.forename: O E
authors.initials: OE
authors.lastname: Varnier
authors.forename: O
authors.initials: O
authors.lastname: Muratore
authors.forename: S P
authors.initials: SP
authors.lastname: Raffanti
authors.forename: G C
authors.initials: GC
authors.lastname: Schito
mesh_terms: D049933:Aminocoumarins; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002460:Cell Line; D003374:Coumarins / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D009052:Leukemia Virus, Murine / Q000187:drug effects* / Q000254:growth & development; D051379:Mice; D014779:Virus Replication / Q000187:drug effects
chemical_list: D049933:Aminocoumarins; D000900:Anti-Bacterial Agents; D003374:Coumarins; C004628:coumermycin