[Analysis of the factors affecting cardiac output in exclusion of the sino-carotid reflexogenic area].
In acute experiments on cats, the character and mechanisms of changes of the heart pumping function were studied in suppression of the carotid sinus baroreceptors with occlusion of the carotid arteries. In 65% of tests the cardiac output was reduced. Changes of venous return, at that, were diverse and opposite to those of the cardiac output in 50% of observations. Neither vagotomy, nor blockade of beta-adreno- and M-cholinoreceptors affected the character of cardiac output changes. The role of maximal responses of arterial pressure in forming of the cardiac output shifts in sino-carotid reflex, is discussed.
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D000818:Animals; D001285:Atropine / Q000494:pharmacology; D001794:Blood Pressure; D002302:Cardiac Output / Q000187:drug effects; D002339:Carotid Arteries / Q000502:physiology; D002346:Carotid Sinus / Q000502:physiology*; D002415:Cats; D009200:Myocardial Contraction; D011433:Propranolol / Q000494:pharmacology; D011943:Receptors, Adrenergic, beta / Q000187:drug effects; D011950:Receptors, Cholinergic / Q000187:drug effects; D012018:Reflex / Q000502:physiology*; D013564:Sympathetic Nervous System / Q000502:physiology; D014630:Vagus Nerve / Q000502:physiology
D011943:Receptors, Adrenergic, beta; D011950:Receptors, Cholinergic; D001285:Atropine; D011433:Propranolol
Analiz faktorov, vliiaiushchikh na serdechnyĭ vybros pri vykliuchenii sinokarotidnoĭ refleksogennoĭ zony.