Serial study of T-lymphocyte subsets in women during very early pregnancy.
The aim of this serial study was to define variations in T-lymphocyte populations during the first weeks of pregnancy. Results obtained with 14 women pregnant after artificial insemination show that the CD4+ population decreased significantly as soon as the fourth week. This decrease was concomitant with the HCG peak and could be compatible with certain immunological mechanisms participating in tolerance to the fetal graft.
Degenne
D
D
Laboratoire d'Immunologie, Faculté de Médecine, Tours, France.
Canepa
S
S
Lecomte
C
C
Renoux
M
M
Bardos
P
P
D000328:Adult; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis; D006063:Chorionic Gonadotropin / Q000097:blood; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D010641:Phenotype; D011247:Pregnancy / Q000276:immunology*; D011261:Pregnancy Trimester, First; D013601:T-Lymphocytes / Q000032:analysis / Q000145:classification*; D006377:T-Lymphocytes, Helper-Inducer / Q000032:analysis
D000945:Antigens, Differentiation, T-Lymphocyte; D006063:Chorionic Gonadotropin