A comparison of anti-inflammatory, analgesic and ulcerogenic action of tryptamide, ibuprofen and piroxicam.
Tryptamide, similarly to ibuprofen and piroxicam, shows anti-inflammatory and analgesic properties. Though tryptamide is much less potent than the standard drugs, its therapeutical indices are much more favorable.
Kulig
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Central Research Laboratory, Cracow Pharmaceutical Works Polfa, Poland.
Zaczyńska-Kostrakiewicz
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M
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology* / Q000633:toxicity; D002351:Carrageenan / Q000633:toxicity; D005753:Gastric Mucosa / Q000187:drug effects; D007052:Ibuprofen / Q000494:pharmacology* / Q000633:toxicity; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009536:Niacinamide / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000633:toxicity; D010894:Piroxicam / Q000494:pharmacology* / Q000633:toxicity; D051381:Rats; D011919:Rats, Inbred Strains; D014363:Tryptamines / Q000494:pharmacology* / Q000633:toxicity
D000894:Anti-Inflammatory Agents, Non-Steroidal; D014363:Tryptamines; D010894:Piroxicam; D009536:Niacinamide; C057564:tryptamide; D002351:Carrageenan; D007052:Ibuprofen