title: Hypertension in children. Increased efficacy of technetium Tc 99m succimer in screening for renal disease.
abstract: Renal scintigraphy with technetium Tc 99m succimer (DMSA) and technetium Tc 99m pentetate (DTPA) was used to study 80 hypertensive pediatric and adolescent patients. Renal abnormalities such as asymmetry of function, size, or shape were identified in 13 patients. Both excretory urography and technetium Tc 99m pentetate studies were successful in detecting 54% of the abnormalities in patients studied; technetium Tc 99m succimer identified 92%. The accuracy of the latter was 96%, with a specificity of 97%. The ability of technetium Tc 99m succimer renal scintigraphy to identify accurately the presence or absence of renal abnormalities warrants its inclusion in the initial examination of pediatric and adolescent patients with hypertension.
authors.forename: P R
authors.initials: PR
authors.lastname: Rosen
authors.forename: S
authors.initials: S
authors.lastname: Treves
authors.forename: J
authors.initials: J
authors.lastname: Ingelfinger
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003951:Diagnostic Errors; D005069:Evaluation Studies as Topic; D006801:Humans; D006977:Hypertension, Renal / Q000000981:diagnostic imaging*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D004369:Pentetic Acid; D011877:Radionuclide Imaging; D004113:Succimer; D013438:Sulfhydryl Compounds; D013667:Technetium; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D016284:Technetium Tc 99m Pentetate; D014567:Urography / Q000379:methods
chemical_list: D013438:Sulfhydryl Compounds; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D013667:Technetium; D004369:Pentetic Acid; D004113:Succimer; D016284:Technetium Tc 99m Pentetate