Histocytologic diagnosis of pancreatic cancer by percutaneous aspiration biopsy under ultrasonic guidance.
Percutaneous aspiration biopsy of the pancreas using a heparinized 22-gauge fine needle was performed under ultrasonic guidance in five patients with benign pancreatic diseases and in 18 patients with pancreatic cancer. Using a heparinized needle and syringe, it was possible to make good smears containing abundant tumor cells and to obtain small tissue specimens. Using egg albumin as binding material, a new cell-block technic was developed to conveniently obtain histologic specimens. In this way, a correct diagnosis was made cytologically in all 23 patients suspected of having a pancreatic malignancy. Histologic specimens were obtained in 22 (95.6%) our of 23 patients. A correct diagnosis was established histologically in all patients from whom histologic materials were obtained. This procedure thus has proved a very reliable method for diagnosing pancreatic cancer.
Yamamoto
R
R
Tatsuta
M
M
Noguchi
S
S
Kasugai
H
H
Okano
Y
Y
Okuda
S
S
Wada
A
A
Tamura
H
H
D000230:Adenocarcinoma / Q000473:pathology; D002288:Adenocarcinoma, Mucinous / Q000473:pathology; D000368:Aged; D001707:Biopsy, Needle / Q000379:methods*; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000166:cytology; D010182:Pancreatic Diseases / Q000175:diagnosis / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000473:pathology*; D010195:Pancreatitis / Q000473:pathology; D011677:Punctures / Q000379:methods; D014463:Ultrasonography
D006493:Heparin