Constitutional mosaic t(2;7)(q33;p22) and other rearrangements in a girl with Wilms' tumor.
A 2-year-old girl with sporadic unilateral Wilms' tumor (WT) not associated with aniridia was found to have, besides other chromosome abnormalities, a t(2;7)(q33;p22) in 6% of her lymphocytes. A comparison with 7 previous WT cases without aniridia in whom diverse chromosomal aberrations were present, reveals a wide heterogeneity and lead us to tentatively classify such changes as causal, secondary, and casual.
Rivera
H
H
Ruiz
C
C
García-Cruz
D
D
Rolón
A
A
Arroyo
J
J
Cantú
J M
JM
D002675:Child, Preschool; D002900:Chromosomes, Human, 1-3; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D007621:Karyotyping; D009030:Mosaicism; D009396:Wilms Tumor / Q000235:genetics*