title: Prediction of an ATP reactive center in the small subunit, gpNu1, of the phage lambda terminase enzyme.
abstract: The small subunit of the bacteriophage lambda terminase enzyme, the product of the phage's Nu1 gene, is shown to contain amino acid segments homologous to those present in a large number of ATPases. In keeping with these predictions, the purified protein has been found to hydrolyze ATP with a relatively low turnover number. Terminase holoenzyme is a known ATPase, and the biochemical significance of an ATP-interactive center situated in the gpNu1 subunit is discussed.
authors.affiliation: Department of Medical Genetics, University of Toronto, Canada.
authors.forename: A
authors.initials: A
authors.lastname: Becker
authors.forename: M
authors.initials: M
authors.lastname: Gold
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism*; D000595:Amino Acid Sequence; D010582:Bacteriophage lambda / Q000201:enzymology*; D004706:Endodeoxyribonucleases / Q000378:metabolism*; D008969:Molecular Sequence Data; D011487:Protein Conformation
chemical_list: D000255:Adenosine Triphosphate; D004706:Endodeoxyribonucleases; C030894:terminase; D000251:Adenosine Triphosphatases