title: A fragment of the simian virus 40 early genome can induce tumors in nude mice.
abstract: Cell lines transformed by simian virus 40 mutant F8dl (deleted from 0.168 to 0.424 map units, corresponding to the carboxy-terminal 62% of the wild-type simian virus 40 large tumor antigen) are tumorigenic in nude mice. Four of five C3H10T1/2 cell lines transformed by F8dl were tumorigenic in nude mice, whereas two of two wild-type transformants were tumorigenic.
authors.forename: S
authors.initials: S
authors.lastname: Pan
authors.forename: L M
authors.initials: LM
authors.lastname: Sompayrac
authors.forename: B B
authors.initials: BB
authors.lastname: Knowles
authors.forename: K J
authors.initials: KJ
authors.lastname: Danna
mesh_terms: D000818:Animals; D002471:Cell Transformation, Neoplastic; D005814:Genes, Viral; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D013539:Simian virus 40 / Q000235:genetics*