title: A new tool for peptide separation.
abstract: A family of reagents has been developed (Pep-Seps) which provide separations of peptides based upon the presence or absence of a single type of amino acid. This separation is achieved through a reversible, covalent attachment of the peptide to the Pep-Seps reagents. Pep-Seps provide a more specific separation than most forms of HPLC and may be used to complement HPLC in peptide separations and isolations. Several specific applications will be discussed.
authors.affiliation: Applied Protein Technologies, Inc., Cambridge, MA 02139.
authors.forename: S G
authors.initials: SG
authors.lastname: Magil
authors.forename: S L
authors.initials: SL
authors.lastname: Early
authors.forename: C
authors.initials: C
authors.lastname: Novak
authors.forename: M J
authors.initials: MJ
authors.lastname: Horn
mesh_terms: D001120:Arginine / Q000737:chemistry; D001920:Bradykinin / Q000302:isolation & purification; D003545:Cysteine / Q000737:chemistry; D004743:Enkephalin, Leucine / Q000302:isolation & purification; D004744:Enkephalin, Methionine / Q000302:isolation & purification; D008715:Methionine / Q000737:chemistry; D008863:Microspheres; D010455:Peptides / Q000302:isolation & purification*; D012680:Sensitivity and Specificity; D014364:Tryptophan / Q000737:chemistry
chemical_list: D010455:Peptides; D004744:Enkephalin, Methionine; D004743:Enkephalin, Leucine; D014364:Tryptophan; D001120:Arginine; D008715:Methionine; D003545:Cysteine; D001920:Bradykinin