Bilateral nephroblastoma associated with a 3;17 translocation.
Cultured cells from the tumor of a child with bilateral nephroblastoma were studied cytogenetically. All mitoses observed showed the same male karyotype, 46,XY,t(3;17). This translocation constitutes a newly discovered rearrangement that has not been reported previously either in nephroblastoma or in other neoplastic processes.
Soulie
J
J
Rousseau-Merck
M F
MF
Mouly
H
H
Nezelof
C
C
D002871:Chromosome Banding; D002900:Chromosomes, Human, 1-3; D002902:Chromosomes, Human, 16-18; D006801:Humans; D007223:Infant; D007621:Karyotyping; D007680:Kidney Neoplasms / Q000235:genetics* / Q000473:pathology; D008297:Male; D014178:Translocation, Genetic; D009396:Wilms Tumor / Q000235:genetics* / Q000473:pathology