Glucocorticoid receptor regulation.
Glucocorticoids, like other classes of steroid hormones, must bind to cellular receptors in order to exert their effects. Because of this central role in mediating hormone action, it is important to elucidate those factors that control receptor content. The purpose of this minireview is to summarize the recent work that explores the mechanisms through which cells modulate their glucocorticoid receptor binding capacity.
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D000255:Adenosine Triphosphate / Q000378:metabolism; D000315:Adrenalectomy; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000818:Animals; D002453:Cell Cycle; D002458:Cell Fractionation; D002460:Cell Line; D002999:Clone Cells / Q000378:metabolism; D005938:Glucocorticoids / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D010084:Oxidation-Reduction; D010766:Phosphorylation; D011965:Receptors, Glucocorticoid / Q000502:physiology*; D011987:Receptors, Steroid / Q000502:physiology*; D013997:Time Factors
D005938:Glucocorticoids; D011965:Receptors, Glucocorticoid; D011987:Receptors, Steroid; D000255:Adenosine Triphosphate; D000324:Adrenocorticotropic Hormone