Synthesis and pharmacological characterization of 5-(2-dodecylphenyl)-4,6-dithianonanedioic acid and 5-[2-(8-phenyloctyl)phenyl]-4,6-dithianonanedioic acid: prototypes of a novel class of leukotriene antagonists.
Perchonock
C D
CD
McCarthy
M E
ME
Erhard
K F
KF
Gleason
J G
JG
Wasserman
M A
MA
Muccitelli
R M
RM
DeVan
J F
JF
Tucker
S S
SS
Vickery
L M
LM
Kirchner
T
T
D000403:Airway Resistance / Q000187:drug effects; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D002867:Chromones / Q000494:pharmacology; D003998:Dicarboxylic Acids / Q000138:chemical synthesis / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D006168:Guinea Pigs; D008170:Lung Compliance / Q000187:drug effects; D009119:Muscle Contraction / Q000187:drug effects; D018077:Receptors, Leukotriene; D011982:Receptors, Prostaglandin / Q000187:drug effects; D013189:SRS-A / Q000037:antagonists & inhibitors*; D014132:Trachea / Q000502:physiology
D002867:Chromones; D003998:Dicarboxylic Acids; D018077:Receptors, Leukotriene; D011982:Receptors, Prostaglandin; D013189:SRS-A; C006312:FPL 55712; C046471:5-(2-dodecylphenyl)-4,6-dithianonanedioic acid; C046472:5-(2-(8-phenyloctyl)phenyl)-4,6-dithianonanedioic acid