title: Pneumatosis intestinalis in patients after cadaveric kidney transplantation: possible relationship with an active cytomegalovirus infection.
abstract: Four patients are presented with pneumatosis intestinalis following kidney transplantation, all with severe cytomegalovirus (CMV) infection. Two patients had a primary infection and two patients had CMV reactivation. One patient died because of disseminated CMV infection. Two patients had concomitantly an active, non-obstructive duodenal ulcer. In a control population of 17 patients who suffered from a duodenal ulcer post-transplant without any evidence of CMV infection, we could not demonstrate pneumatosis intestinalis. We suggest a possible relationship between pneumatosis intestinalis and active CMV infection. The possible mechanisms responsible for this relationship are discussed.
authors.forename: W J
authors.initials: WJ
authors.lastname: van Son
authors.forename: F J
authors.initials: FJ
authors.lastname: van der Woude
authors.forename: E J
authors.initials: EJ
authors.lastname: van der Jagt
authors.forename: A J
authors.initials: AJ
authors.lastname: Donker
authors.forename: S
authors.initials: S
authors.lastname: Meijer
authors.forename: M J
authors.initials: MJ
authors.lastname: Slooff
authors.forename: T H
authors.initials: TH
authors.lastname: The
authors.forename: A M
authors.initials: AM
authors.lastname: Tegzess
authors.forename: L B
authors.initials: LB
authors.lastname: van der Slikke
mesh_terms: D000328:Adult; D003586:Cytomegalovirus Infections / Q000150:complications*; D004381:Duodenal Ulcer / Q000150:complications; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011006:Pneumatosis Cystoides Intestinalis / Q000209:etiology*