Case reports of individuals with oligospermia and methylene chloride exposures.
Between December 7, 1984 and June, 1986, 34 men with exposure to methylene chloride were evaluated at the Greater Cincinnati Occupational Health Center (GCOHC). Their primary complaint involved problems associated with central nervous system dysfunction. However, 8 of the 34 men complained of testicular, epididymal or lower abdominal pain (found on exam to be prostatic in origin) and had clinical histories consistent with infertility. Semen specimens from four volunteers were found to be in the subfertile or infertile range with regard to motility, morphology and sperm density.
Kelly
M
M
Occupational/Internal Medicine, University of Cincinnati School of Medicine, Ohio 45239.
D000328:Adult; D006801:Humans; D008297:Male; D008752:Methylene Chloride / Q000009:adverse effects*; D009784:Occupational Diseases / Q000139:chemically induced*; D009845:Oligospermia / Q000139:chemically induced*; D010146:Pain / Q000209:etiology; D011467:Prostate / Q000503:physiopathology; D012189:Retrospective Studies
D008752:Methylene Chloride