title: Gastro-oesophageal reflux associated with nifedipine.
abstract: A 57-year-old woman presented with a 3-week history of dysphagia for solids, 6 months after starting treatment with nifedipine. Endoscopy demonstrated oesophagitis and a benign oesophageal stricture. Twenty-four-hour ambulatory pH monitoring demonstrated decreased acid reflux 8 weeks after withdrawal of nifedipine, with coincidental symptomatic and endoscopic improvement. Nifedipine may induce, or aggravate, pre-existing, gastro-oesophageal reflux.
authors.affiliation: Department of Surgery, Royal Lancaster Infirmary, UK.
authors.forename: L R
authors.initials: LR
authors.lastname: Jenkinson
authors.forename: T L
authors.initials: TL
authors.lastname: Norris
authors.forename: A
authors.initials: A
authors.lastname: Watson
mesh_terms: D000328:Adult; D003680:Deglutition Disorders / Q000188:drug therapy; D005260:Female; D005764:Gastroesophageal Reflux / Q000139:chemically induced*; D006801:Humans; D008875:Middle Aged; D009543:Nifedipine / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D009543:Nifedipine