Disulfiram-induced hepatitis. Report of two cases and review of the literature.
Two cases of disulfiram-induced hepatitis are presented. Both cases had prompt recurrence of abnormal liver function tests after rechallenge with small doses of the drug. All cases of disulfiram-induced hepatotoxicity reported in the English literature are reviewed.
Bartle
W R
WR
Fisher
M M
MM
Kerenyi
N
N
D000328:Adult; D000437:Alcoholism / Q000188:drug therapy; D000469:Alkaline Phosphatase / Q000378:metabolism; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D003484:Cyanamide / Q000627:therapeutic use; D004221:Disulfiram / Q000009:adverse effects*; D004342:Drug Hypersensitivity; D004804:Eosinophils; D005260:Female; D006801:Humans; D008099:Liver / Q000187:drug effects / Q000201:enzymology / Q000473:pathology; D008297:Male; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced; D000637:Transaminases / Q000378:metabolism
D003484:Cyanamide; D000637:Transaminases; D000469:Alkaline Phosphatase; D004221:Disulfiram