Disseminated superficial porokeratosis and immunosuppression.
We present a patient who developed skin lesions typical of disseminated superficial porokeratosis (DSP) while on immunosuppressive therapy for pemphigus foliaceus. Phototesting with artificial light sources did not have any effect on the DSP lesions. The literature describing occurrence of DSP on immunosuppression is reviewed and possible pathogenetic mechanisms are discussed.
Neumann
R A
RA
Department of Dermatology II, University of Vienna, Austria.
Knobler
R M
RM
Metze
D
D
Jurecka
W
W
D000368:Aged; D001379:Azathioprine / Q000009:adverse effects* / Q000627:therapeutic use; D003875:Drug Eruptions / Q000209:etiology*; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D007642:Keratosis / Q000209:etiology* / Q000473:pathology; D008297:Male; D010392:Pemphigus / Q000188:drug therapy; D011241:Prednisone / Q000009:adverse effects* / Q000627:therapeutic use; D012867:Skin / Q000473:pathology
D001379:Azathioprine; D011241:Prednisone