Brachial plexus neuropathy following high-dose cytarabine in acute monoblastic leukemia.
We describe brachial plexus neuropathy with high-dose cytarabine (Ara-C) therapy in a man who had acute monoblastic leukemia. Signs and symptoms of brachial plexus neuropathy appeared on two occasions within hours of exposure to high-dose Ara-C. Central nervous system complications have been described following systemic and intrathecal Ara-C. High-dose Ara-C has not been implicated previously as a cause of brachial plexus neuropathy.
Scherokman
B
B
Filling-Katz
M R
MR
Tell
D
D
D001132:Arm; D001917:Brachial Plexus / Q000187:drug effects*; D003561:Cytarabine / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007948:Leukemia, Monocytic, Acute / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000187:drug effects / Q000293:injuries; D009423:Nervous System Neoplasms / Q000556:secondary; D009460:Neurologic Examination; D010146:Pain / Q000139:chemically induced; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced; D012008:Recurrence; D013997:Time Factors
D003561:Cytarabine