Rapid conjugation in an extremely rapid hydroxylator of debrisoquine: a case report supporting a coregulation of certain phase I and II metabolic reactions.
Bertilsson
L
L
Department of Clinical Pharmacology, Karolinska Institute, Huddinge Hospital, Sweden.
Aberg-Wistedt
A
A
Dumont
E
E
Lundström
J
J
D000328:Adult; D000928:Antidepressive Agents / Q000378:metabolism; D003647:Debrisoquin / Q000378:metabolism* / Q000493:pharmacokinetics; D003891:Desipramine / Q000378:metabolism; D005260:Female; D005965:Glucuronates / Q000378:metabolism; D006801:Humans; D006900:Hydroxylation; D066298:In Vitro Techniques; D007538:Isoniazid / Q000378:metabolism; D007546:Isoquinolines / Q000378:metabolism*; D010076:Oxazepam / Q000378:metabolism; D015031:Zimeldine / Q000031:analogs & derivatives / Q000494:pharmacology
D000928:Antidepressive Agents; D005965:Glucuronates; D007546:Isoquinolines; D015031:Zimeldine; C017578:norzimelidine; D010076:Oxazepam; D003891:Desipramine; D007538:Isoniazid; D003647:Debrisoquin