HPLC quantitation of the six main components of teicoplanin in biological fluids.
Teicoplanin, a new glycopeptide antibiotic belonging to the same class as vancomycin, is a mixture of six main components, designated A3, A2-1, A2-2, A2-3, A2-4 and A2-5. An assay method by higher performance liquid chromatography (HPLC) has been devised to separate and monitor each of these components in blood and urine.
Jehl
F
F
Institute of Bacteriology, Department of Medicine, Strasbourg, France.
Monteil
H
H
Tarral
A
A
D000900:Anti-Bacterial Agents / Q000032:analysis* / Q000097:blood / Q000652:urine; D001412:Bacillus subtilis / Q000187:drug effects; D001681:Biological Assay; D002851:Chromatography, High Pressure Liquid; D006020:Glycopeptides / Q000032:analysis / Q000097:blood / Q000652:urine; D006801:Humans; D017334:Teicoplanin
D000900:Anti-Bacterial Agents; D006020:Glycopeptides; D017334:Teicoplanin