title: Magnetic resonance imaging of intracranial tumors using gadolinium-DTPA. Initial experience with fast imaging.
abstract: One hundred and fifty gadolinium(Gd)-DTPA studies in patients with intracranial tumors were performed. In meningiomas (n = 37) Gd-DTPA is useful to delineate isointense tumors. In acoustic neuromas (n = 16) Gd-DTPA helps to identify intracanalicular tumor tissue. In pituitary adenomas (n = 16) para- or suprasellar tumor extension can be better appreciated after Gd-DTPA injection. In glioblastomas (n = 23) Gd-DTPA provides data on differential diagnosis through the characteristic shape of enhancement. In a variety of tumor types the high contrast between enhancing tumor tissue and adjacent structures facilitates therapy planning. Fast imaging sequences now allow for dynamic Gd-DTPA studies. The time-course of enhancement may increase specificity of magnetic resonance imaging.
authors.affiliation: Department of Radiology, FB Medizin, Schering AG, Berlin, West Germany.
authors.forename: H P
authors.initials: HP
authors.lastname: Niendorf
authors.forename: R
authors.initials: R
authors.lastname: Felix
authors.forename: M
authors.initials: M
authors.lastname: Laniado
authors.forename: W
authors.initials: W
authors.lastname: Schörner
authors.forename: W
authors.initials: W
authors.lastname: Kornmesser
authors.forename: C
authors.initials: C
authors.lastname: Claussen
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis*; D003287:Contrast Media; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D009942:Organometallic Compounds; D004369:Pentetic Acid
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA