title: Validation of thermal techniques for measurement of pelvic organ blood flows in the nonpregnant sheep: comparison with transit-time ultrasonic and microsphere measurements of blood flow.
abstract: Data obtained from a thermal system capable of measuring changes in organ temperature as well as tissue thermal clearance in the uterus and vagina have been compared with blood flow measured continuously with a transit-time ultrasound volume-flow sensor placed around the common internal iliac artery and intermittently with radioactive microspheres in the chronically instrumented nonpregnant sheep. Temperature changes in both the uterus and the vagina correlated well with blood flow changes measured by both techniques after intravenous administration of estradiol or norepinephrine. Thermal clearance did not correlate well with blood flow in the vagina or uterus. These methods may have value in the investigation of blood flow patterns in various clinical situations such as the pelvic pain syndrome and early pregnancy.
authors.affiliation: Department of Obstetrics and Gynaecology, St. Mary's Hospital Medical School, London.
authors.forename: N J
authors.initials: NJ
authors.lastname: Randall
authors.forename: R W
authors.initials: RW
authors.lastname: Beard
authors.forename: I A
authors.initials: IA
authors.lastname: Sutherland
authors.forename: J P
authors.initials: JP
authors.lastname: Figueroa
authors.forename: C J
authors.initials: CJ
authors.lastname: Drost
authors.forename: P W
authors.initials: PW
authors.lastname: Nathanielsz
mesh_terms: D000818:Animals; D005260:Female; D007083:Iliac Artery / Q000502:physiology; D008722:Methods; D008863:Microspheres; D010388:Pelvis / Q000098:blood supply*; D011868:Radioisotopes; D012039:Regional Blood Flow; D012212:Rheology; D012756:Sheep; D013696:Temperature; D013814:Thermal Conductivity; D014599:Uterus / Q000098:blood supply / Q000502:physiology; D014621:Vagina / Q000098:blood supply / Q000502:physiology
chemical_list: D011868:Radioisotopes