Construction of linkage maps with DNA markers for human chromosomes.
DNA markers and sampling of three-generation families can be used to construct complete linkage maps of human chromosomes. This is important in mapping disease loci and in determining the genetic or environmental component of a disease.
White
R
R
Leppert
M
M
Bishop
D T
DT
Barker
D
D
Berkowitz
J
J
Brown
C
C
Callahan
P
P
Holm
T
T
Jerominski
L
L
D002874:Chromosome Mapping; D002877:Chromosomes, Human; D004262:DNA Restriction Enzymes; D030342:Genetic Diseases, Inborn / Q000235:genetics*; D008040:Genetic Linkage; D006579:Heterozygote; D006801:Humans; D010375:Pedigree; D011995:Recombination, Genetic
D004262:DNA Restriction Enzymes