Effect of thyroxine on hepatic glucose-6-phosphatase activity and glycogen content of toad (Bufo melanostictus) and Lata fish (Ophicephalus punctatus) at different stages of life.
The effects of thyroxine (T4) on hepatic glucose-6-phosphatase activity and glycogen content in toad (Bufo melanostictus) and Lata fish (Ophicephalus punctatus) were studied in order to show the difference, if any in the enzyme activity and glycogen metabolism in their liver. Thyroxine injections (1 microgram/g) for five consecutive days caused a reduction in hepatic glucose-6-phosphatase activity and glycogen content in toads of immature, juvenile and adult stages. In contrast, Lata fish of different stages showed an enhancement of hepatic glucose-6-phosphatase activity after T4 treatment (1 microgram/g, 5 injections). The liver glycogen content in Lata fish of different age groups was found to be reduced after T4 injections, but not so much as in the toad.
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D000818:Animals; D002025:Bufonidae / Q000254:growth & development* / Q000378:metabolism; D005399:Fishes / Q000254:growth & development* / Q000378:metabolism; D005952:Glucose-6-Phosphatase / Q000378:metabolism*; D006003:Glycogen / Q000378:metabolism*; D008099:Liver / Q000201:enzymology* / Q000378:metabolism; D008297:Male; D013974:Thyroxine / Q000494:pharmacology*
D006003:Glycogen; D005952:Glucose-6-Phosphatase; D013974:Thyroxine