Effect of time, degree of saturation, pH and acid concentration of buffer solutions on the rate of in-vitro demineralization of human enamel.
The rate of demineralization of the artificial caries-like process was measured using two methods. The rate calculated from microradiography of the demineralized enamel appeared to be equal to the one calculated from calcium and phosphate analysis of the demineralizing buffer. In small volumes of demineralizing solution, the rate of demineralization decreased with time, due to the increase in saturation of the solution during the demineralization of the enamel. With increasing saturation, with respect to hydroxyapatite, and with increasing pH the rate of demineralization decreased. Increasing acid concentration had a marked influence only at the lower concentrations; a further increase had no effect on the rate of demineralization.
Theuns
H M
HM
van Dijk
J W
JW
Driessens
F C
FC
Groeneveld
A
A
D002021:Buffers; D003731:Dental Caries / Q000378:metabolism; D003743:Dental Enamel / Q000378:metabolism*; D017886:Durapatite; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006882:Hydroxyapatites; D066298:In Vitro Techniques; D008852:Microradiography; D008903:Minerals / Q000378:metabolism*; D008954:Models, Biological; D013997:Time Factors
D002021:Buffers; D006882:Hydroxyapatites; D008903:Minerals; D017886:Durapatite