title: Molecular epidemiology of two US orbiviruses: bluetongue virus and epizootic hemorrhagic disease virus.
abstract: The degree of relatedness between 4 US serotypes (10, 11, 13 and 17) of bluetongue (BT) virus (BTV) were determined by both oligonucleotide fingerprint analyses of double-stranded (ds) RNA as well as tryptic peptide analyses of viral coded polypeptides. Similar studies were undertaken using different alternate isolates of particular serotypes as well as 2 serotypes (1 and 2) of epizootic hemorrhagic disease (EHD) virus (EHDV), a closely related serogroup of orbiviruses. The results indicate that all BT viruses are genetically related to each other and although EHDV-1 and EHDV-2 originated from a common gene pool, the 2 serogroups, EHDV and BTV, are not genetically interactive.
authors.forename: P
authors.initials: P
authors.lastname: Roy
authors.forename: K
authors.initials: K
authors.lastname: Sugiyama
authors.forename: C D
authors.initials: CD
authors.lastname: Rao
authors.forename: J
authors.initials: J
authors.lastname: Kusari
authors.forename: M
authors.initials: M
authors.lastname: Purdy
authors.forename: E
authors.initials: E
authors.lastname: Collisson
mesh_terms: D001820:Bluetongue virus / Q000145:classification / Q000235:genetics; D008970:Molecular Weight; D009843:Oligoribonucleotides / Q000032:analysis; D010446:Peptide Fragments / Q000032:analysis; D012330:RNA, Double-Stranded / Q000032:analysis; D012367:RNA, Viral / Q000032:analysis; D012087:Reoviridae / Q000145:classification / Q000235:genetics*; D012703:Serotyping; D013045:Species Specificity; D014481:United States; D014764:Viral Proteins / Q000032:analysis
chemical_list: D009843:Oligoribonucleotides; D010446:Peptide Fragments; D012330:RNA, Double-Stranded; D012367:RNA, Viral; D014764:Viral Proteins