Stereostructure-activity relationship of opioid agonist and antagonist bivalent ligands. Evidence for bridging between vicinal opioid receptors.
Portoghese
P S
PS
Larson
D L
DL
Yim
C B
CB
Sayre
L M
LM
Ronsisvalle
G
G
Lipkowski
A W
AW
Takemori
A E
AE
Rice
K C
KC
Tam
S W
SW
D000818:Animals; D001921:Brain / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D004723:Endorphins / Q000494:pharmacology*; D006168:Guinea Pigs; D007082:Ileum / Q000187:drug effects; D009271:Naltrexone / Q000031:analogs & derivatives / Q000494:pharmacology; D010111:Oxymorphone / Q000031:analogs & derivatives / Q000494:pharmacology; D011957:Receptors, Opioid / Q000187:drug effects / Q000502:physiology; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D004723:Endorphins; D011957:Receptors, Opioid; D009271:Naltrexone; C035438:beta-naltrexamine; C036406:oxymorphamine; D010111:Oxymorphone