Contact sensitivity to gentamicin-hydrocortisone ear drops.
Patch testing of ten patients who had been treated with gentamicin-hydrocortisone ear drops for active chronic suppurative otitis media showed evidence of contact sensitivity in five. Positive skin tests correlated with failure to respond to treatment.
Robinson
P M
PM
E.N.T. Department, Hull Royal Infirmary.
D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003877:Dermatitis, Contact / Q000209:etiology*; D003875:Drug Eruptions / Q000209:etiology*; D004359:Drug Therapy, Combination; D005839:Gentamicins / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D006854:Hydrocortisone; D010035:Otitis Media, Suppurative / Q000188:drug therapy; D010328:Patch Tests
D000893:Anti-Inflammatory Agents; D005839:Gentamicins; D006854:Hydrocortisone