title: MZ15, a monoclonal antibody recognizing keratan sulphate, stains chick tendon.
abstract: Biochemical, morphometric and electron histochemical methods have failed to demonstrate the presence in tendon of keratan sulphate, a common component of connective tissue proteoglycans. Using a monoclonal antibody specific for keratan sulphate, a positive localization of this molecule was made in the gastrocnemius tendon of stage 44 chicken embryos both at the light and electron microscopical levels.
authors.affiliation: Institute of Orthopaedics, Royal National Orthopaedic Hospital, Stanmore, Middlesex, UK.
authors.forename: F M
authors.initials: FM
authors.lastname: Craig
authors.forename: J R
authors.initials: JR
authors.lastname: Ralphs
authors.forename: G
authors.initials: G
authors.lastname: Bentley
authors.forename: C W
authors.initials: CW
authors.lastname: Archer
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal; D000918:Antibody Specificity; D002642:Chick Embryo; D006025:Glycosaminoglycans / Q000032:analysis*; D007150:Immunohistochemistry; D007632:Keratan Sulfate / Q000032:analysis* / Q000276:immunology; D008854:Microscopy, Electron; D008856:Microscopy, Fluorescence; D013710:Tendons / Q000032:analysis* / Q000648:ultrastructure
chemical_list: D000911:Antibodies, Monoclonal; D006025:Glycosaminoglycans; D007632:Keratan Sulfate