title: Why are non-steroidal anti-inflammatory drugs important in peptic ulceration?
abstract: The pathogenetic role of non-steroidal anti-inflammatory drugs (NSAIDs) in peptic ulcer disease is reviewed, on the basis of available experimental and epidemiological knowledge. In addition, original clinical data are provided concerning the prophylactic and therapeutic role of the H2-receptor antagonists ranitidine and cimetidine, and colloidal bismuth subcitrate, in the treatment of NSAID-associated peptic lesions in rheumatic patients.
authors.affiliation: Gastrointestinal Unit, L. Sacco Hospital, Milan, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Bianchi Porro
authors.forename: F
authors.initials: F
authors.lastname: Pace
authors.forename: I
authors.initials: I
authors.lastname: Caruso
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D006801:Humans; D010437:Peptic Ulcer / Q000139:chemically induced* / Q000503:physiopathology; D012216:Rheumatic Diseases / Q000150:complications / Q000188:drug therapy
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal