Beta-endorphin-like immunoreactivity increases in cerebrospinal fluid of acute head-injured patients.
beta-endorphin-like immunoreactivity (beta-ELI) was measured in cerebrospinal fluid (CSF) of 36 acute head-injured patients and 12 patients without head injury as controls. The mean level of beta-ELI in CSF of controls, mild cerebral contusions, and severe cerebral contusion patients were 51.9 +/- 5.6 pg/ml, 110.5 +/- 14.5 pg/ml, and 173.8 +/- 20.1 pg/ml respectively, with significant difference between them. The results also showed that beta-ELI may reflect the prognosis of acute head-injured patients.
Yao
J J
JJ
Department of Neurosurgery, Chang Zheng Hospital, Second Military Medical College, Shanghai, People's Republic of China.
Cheng
Z
Z
Ce
C C
CC
Hai
W C
WC
Xiang
Z Y
ZY
Cheng
L B
LB
D001930:Brain Injuries / Q000134:cerebrospinal fluid; D006259:Craniocerebral Trauma / Q000134:cerebrospinal fluid*; D005260:Female; D006801:Humans; D008297:Male; D012016:Reference Values; D001615:beta-Endorphin / Q000134:cerebrospinal fluid*
D001615:beta-Endorphin