title: Ribosomal DNA inheritance and recombination in Neurospora crassa.
abstract: The genetic segregation of ribosomal DNA (rDNA) in Neurospora crassa was analyzed by exploiting restriction fragment length polymorphisms in the nontranscribed spacer (NTS) sequences of nine laboratory wild-type strains and wild-collected strains. In an analysis of random spore progeny from seven crosses, and of ordered tetrads from two of those crosses the rDNA was shown to be inherited in a simple, stable Mendelian fashion, exhibiting an approximately 1:1 ratio of the two parental rDNA types. No meiotic recombinants were detected among the progeny, indicating that non-sister-chromatid crossing over is highly suppressed in the rDNA region. The basis for this suppression of meiotic recombination is not known.
authors.affiliation: Biology Department, Reed College, Portland, OR 97202.
authors.forename: P J
authors.initials: PJ
authors.lastname: Russell
authors.forename: R C
authors.initials: RC
authors.lastname: Petersen
authors.forename: S
authors.initials: S
authors.lastname: Wagner
mesh_terms: D003433:Crosses, Genetic; D003434:Crossing Over, Genetic; D004275:DNA, Ribosomal / Q000235:genetics*; D005800:Genes, Fungal; D008540:Meiosis; D009491:Neurospora / Q000235:genetics*; D009492:Neurospora crassa / Q000166:cytology / Q000235:genetics*; D011995:Recombination, Genetic
chemical_list: D004275:DNA, Ribosomal