title: Effect of exhaustive exercise on liver mitochondrial function in the rat.
abstract: The oxidative and phosphorylative function of rat liver mitochondria after exhaustive exercise was investigated. The stimulation of state 4 respiration (without ADP) with NADH and FADH2 dependent substrates was demonstrated. The reduction in RCR ratio (the rate of oxidation in state 3/the rate of oxidation in state 4) and enhanced activity of oligomycin sensitive ATP-ase was also found. The results suggest an inhibition of liver mitochondrial phosphorylative activity in rats exercised till exhaustion.
authors.affiliation: Department of Physiology, School of Medicine, Białystok.
authors.forename: J W
authors.initials: JW
authors.lastname: Bielecki
authors.forename: E
authors.initials: E
authors.lastname: Pawlicka
authors.forename: J
authors.initials: J
authors.lastname: Górski
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D004734:Energy Metabolism; D005221:Fatigue / Q000378:metabolism*; D008297:Male; D008930:Mitochondria, Liver / Q000378:metabolism*; D010085:Oxidative Phosphorylation; D010101:Oxygen Consumption; D005082:Physical Exertion; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D000251:Adenosine Triphosphatases