title: [Problems of cellular activity regulation by secondary messengers].
abstract: The paper surveys the data obtained during the last years in the Laboratory of Regulation of Cellular Activity of the Institute of Molecular Biology. The data mostly concern the enzymes taking part in metabolism and in biological action of the secondary messengers, as well as the mechanisms of regulation of some metabolic pathways in the cultured cells. The results pertinent to the mechanisms of chromatin condensation and based on this genetic control processes are also discussed.
authors.forename: E S
authors.initials: ES
authors.lastname: Severin
authors.forename: B O
authors.initials: BO
authors.lastname: Glotov
authors.forename: S M
authors.initials: SM
authors.lastname: Dudkin
authors.forename: A V
authors.initials: AV
authors.lastname: Itkes
authors.forename: S N
authors.initials: SN
authors.lastname: Kochetkov
mesh_terms: D015088:2',5'-Oligoadenylate Synthetase / Q000378:metabolism; D000494:Allosteric Regulation; D000595:Amino Acid Sequence; D000818:Animals; D001921:Brain / Q000378:metabolism; D002118:Calcium / Q000378:metabolism; D002147:Calmodulin / Q000378:metabolism*; D002843:Chromatin / Q000378:metabolism; D000242:Cyclic AMP / Q000378:metabolism*; D004789:Enzyme Activation / Q000187:drug effects; D004837:Epinephrine / Q000494:pharmacology; D006657:Histones / Q000378:metabolism; D006728:Hormones / Q000502:physiology*; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D051379:Mice; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism; D011487:Protein Conformation; D011494:Protein Kinases / Q000378:metabolism*; D013154:Spleen / Q000378:metabolism; D013806:Theophylline / Q000494:pharmacology
chemical_list: D002147:Calmodulin; D002843:Chromatin; D006657:Histones; D006728:Hormones; D013806:Theophylline; D000242:Cyclic AMP; D011494:Protein Kinases; D015088:2',5'-Oligoadenylate Synthetase; D010727:Phosphoric Diester Hydrolases; D002118:Calcium; D004837:Epinephrine
vernacular_title: Problemy reguliatsii kletochnoĭ aktivnosti posredstvom vtorichnykh messendzherov.