[Biological effects of leakadin].
57 patients with disseminated tumors of various sites received 10 daily doses of 600 mg/m2 leakadin intravenously. The immunostimulating effect was observed (OKT4/OKT8 normalization). The data on leakadin pharmacokinetics are discussed.
Garin
A M
AM
Lichinitser
M R
MR
Dmitrieva
N V
NV
Rubtsov
B I
BI
Leneva
N V
NV
D000276:Adjuvants, Immunologic / Q000493:pharmacokinetics / Q000627:therapeutic use*; D000328:Adult; D000818:Animals; D000970:Antineoplastic Agents / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001388:Aziridines / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001389:Azirines / Q000627:therapeutic use*; D006801:Humans; D007694:Killer Cells, Natural; D007958:Leukocyte Count; D051379:Mice; D008875:Middle Aged; D009369:Neoplasms / Q000097:blood / Q000188:drug therapy*; D009374:Neoplasms, Experimental / Q000097:blood / Q000188:drug therapy*; D050378:T-Lymphocytes, Regulatory
D000276:Adjuvants, Immunologic; D000970:Antineoplastic Agents; D001388:Aziridines; D001389:Azirines; C055240:Leakadine
Biologicheskie éffekty leakadina.