Inhibition of vasopressin secretion during migraine.
Six subjects with a history of increased urinary frequency during migraine were studied. In each case there was a marked diuresis and natriuresis within 12 hours of onset of the headache. This was associated with a significant fall in urinary arginine vasopressin (AVP) (p less than 0.01). Migraine may be associated with altered hypothalamic activity resulting in reduced AVP secretion.
Poole
C J
CJ
Medical Unit, Westminster Hospital, London, UK.
Lightman
S L
SL
D000328:Adult; D001127:Arginine Vasopressin / Q000652:urine*; D009320:Atrial Natriuretic Factor / Q000652:urine; D005260:Female; D006801:Humans; D008875:Middle Aged; D008881:Migraine Disorders / Q000652:urine*; D010121:Oxytocin / Q000652:urine; D014882:Water-Electrolyte Balance
D001127:Arginine Vasopressin; D010121:Oxytocin; D009320:Atrial Natriuretic Factor