title: Human metallothionein-II processed gene is located in region p11----q21 of chromosome 4.
abstract: Metallothionein (MT) genes comprise a multigene family encoding low-molecular-weight, heavy-metal-binding proteins. We have mapped a human MT-II processed gene to chromosome 4, using Southern blotting in combination with a human X mouse hybrid clone panel containing defined subsets of human chromosomes. We have further localized this gene to region p11----q21, using in situ hybridization.
authors.forename: H B
authors.initials: HB
authors.lastname: Lieberman
authors.forename: M
authors.initials: M
authors.lastname: Rabin
authors.forename: P E
authors.initials: PE
authors.lastname: Barker
authors.forename: F H
authors.initials: FH
authors.lastname: Ruddle
authors.forename: U
authors.initials: U
authors.lastname: Varshney
authors.forename: L
authors.initials: L
authors.lastname: Gedamu
mesh_terms: D000818:Animals; D002460:Cell Line; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002905:Chromosomes, Human, 4-5; D004262:DNA Restriction Enzymes; D005796:Genes; D006801:Humans; D006822:Hybrid Cells / Q000166:cytology; D007621:Karyotyping; D008668:Metallothionein / Q000235:genetics*; D051379:Mice; D009693:Nucleic Acid Hybridization; D010957:Plasmids
chemical_list: D008668:Metallothionein; D004262:DNA Restriction Enzymes