Latent herpes simplex virus type 1 DNA contains two copies of the virion DNA joint region.
Southern blot analysis of latent herpes simplex virus DNA detected in mouse brain and digested with a restriction enzyme revealed two copies of the virion DNA joint fragment. Thus, the absence of free ends noted previously in latent herpes simplex virus type 1 DNA is due to joining of the termini.
Rock
D L
DL
Fraser
N W
NW
D000818:Animals; D001921:Brain / Q000382:microbiology; D004279:DNA, Viral / Q000032:analysis*; D051379:Mice; D008807:Mice, Inbred BALB C; D018139:Simplexvirus / Q000235:genetics*
D004279:DNA, Viral