Methyl bromide optic atrophy.
A 32-year-old fumigation assistant developed systemic and neuro-ophthalmic manifestations of methyl bromide poisoning, including increased serum bromide level (6.6 mg/100 ml), paresthesias and burning dysesthesia on his hands and feet, and visual impairment. Ocular examination showed mild bilateral decrease in vision, temporal optic nerve head pallor, severely attenuated visual-evoked response amplitudes and normal latencies, a normal electroretinogram, an abnormal electrooculogram, and a severe deuteranomalous (green) defect on Farnsworth-Munsell 100-hue testing. His vision had not improved 12 months after the initial exposure.
Chavez
C T
CT
Hepler
R S
RS
Straatsma
B R
BR
D000328:Adult; D002908:Chronic Disease; D006801:Humans; D006842:Hydrocarbons, Brominated / Q000506:poisoning*; D008297:Male; D009431:Neural Conduction; D009784:Occupational Diseases; D009887:Ophthalmoscopy; D009896:Optic Atrophy / Q000139:chemically induced* / Q000473:pathology / Q000503:physiopathology; D010523:Peripheral Nervous System Diseases / Q000503:physiopathology; D014792:Visual Acuity
D006842:Hydrocarbons, Brominated; C005218:methyl bromide