[The OKT4/OKT8 ratio in benign monoclonal gammopathies].
The percentages of OKT 4 helper and OKT 8 suppressor lymphocytes were studied in 58 patients in whom a monoclonal protein was accidentally identified in the absence of any clinical signs of multiple myeloma, macroglobulinaemia, amyloidosis or lymphoma. The patients were aged 32-63 and were followed-up for 6 years. The F test used in this study revealed a statistically significant difference between the healthy controls and the patients with BMG in one of the parameters examined: OKT 8. This produced a statistically significant alteration in the OKT 4/OKT 8 ratio.
La Rosa
L
L
U.S.S.L. n. 60, Ospedale di Vimercate, Centro Trasfusionale e Laboratorio di Immunoematologia.
Mattoni
C
C
La Rosa
M
M
D000328:Adult; D000911:Antibodies, Monoclonal; D006801:Humans; D006942:Hypergammaglobulinemia / Q000097:blood*; D007122:Immunoelectrophoresis; D007143:Immunoglobulin Heavy Chains / Q000032:analysis; D007147:Immunoglobulin Light Chains / Q000032:analysis; D008875:Middle Aged; D008998:Monoclonal Gammopathy of Undetermined Significance / Q000097:blood* / Q000276:immunology; D013601:T-Lymphocytes / Q000145:classification*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
D000911:Antibodies, Monoclonal; D007143:Immunoglobulin Heavy Chains; D007147:Immunoglobulin Light Chains
Il rapporto OKT4/OKT8 nelle gammopatie monoclonali benigne.