title: [Effect of thymalin on the development of experimental hyperlipidemia and atherosclerosis].
abstract: Thymalin, which is a polypeptide preparation from thymus, exhibited hypolipidemic and antiatherosclerotic actions in rabbits maintained on a cholesterol-containing diet during three months. At the same time, thymalin caused favourable effect on the functional activity of lymphocytes impaired in hyperlipidemic animals, i.e. it normalized the T-suppressor activity and sensitivity to atherogenic lipoproteins.
authors.forename: V E
authors.initials: VE
authors.lastname: Ryzhenkov
authors.forename: R P
authors.initials: RP
authors.lastname: Ogurtsov
authors.forename: V V
authors.initials: VV
authors.lastname: Trubacheva
authors.forename: V G
authors.initials: VG
authors.lastname: Popov
authors.forename: V P
authors.initials: VP
authors.lastname: Puzyreva
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D001161:Arteriosclerosis / Q000097:blood / Q000276:immunology / Q000517:prevention & control*; D001777:Blood Coagulation / Q000187:drug effects; D002464:Cell Migration Inhibition; D002784:Cholesterol / Q000097:blood; D004036:Diet, Atherogenic; D006949:Hyperlipidemias / Q000097:blood / Q000276:immunology / Q000517:prevention & control*; D007962:Leukocytes / Q000276:immunology; D008055:Lipids / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood / Q000276:immunology; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D011817:Rabbits; D051381:Rats; D050378:T-Lymphocytes, Regulatory / Q000276:immunology; D013951:Thymus Hormones / Q000276:immunology / Q000494:pharmacology*
chemical_list: D000276:Adjuvants, Immunologic; D008055:Lipids; D008079:Lipoproteins, VLDL; D013951:Thymus Hormones; C032805:thymalin; D002784:Cholesterol
vernacular_title: Vliianie timalina na razvitie éksperimental'noĭ giperlipidemii i ateroskleroza.