Synthesis of N-nicotinoyl-tryptamine (tryptamide).
N-Nicotinoyl-tryptamine was synthetized by acylation of tryptamine with mixed nicotinic anhydride. The synthesis of tryptamine via DL-tryptophan decarboxylation in cyclohexanol, in the presence of tetraline oxidation products as the catalyst, was described as well.
Eckstein
M
M
Department of Chemical Technology of Drugs, Academy of Sciences, Kraków, Poland.
Misztal
S
S
Terczyńska
A
A
Sienkiewicz
B
B
Roszkowski
A
A
Adamus
M
M
D000215:Acylation; D002384:Catalysis; D003653:Decarboxylation; D009525:Niacin; D009536:Niacinamide / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D014363:Tryptamines / Q000138:chemical synthesis*
D014363:Tryptamines; D009536:Niacinamide; D009525:Niacin; C057564:tryptamide; C030820:tryptamine