title: A sequence downstream of A-A-U-A-A-A is required for formation of simian virus 40 late mRNA 3' termini in frog oocytes.
abstract: The 3' terminus of simian virus 40 late mRNA is formed by nucleolytic cleavage of an mRNA precursor. In this report we show that efficient cleavage requires a sequence in the 3' flanking region, "downstream" of the highly conserved A-A-U-A-A-A sequence. This sequence is not required for polyadenylylation itself or for accurately positioning the 3' terminus that is formed.
authors.forename: L
authors.initials: L
authors.lastname: Conway
authors.forename: M
authors.initials: M
authors.lastname: Wickens
mesh_terms: D000818:Animals; D001483:Base Sequence; D002872:Chromosome Deletion; D005260:Female; D005796:Genes; D005809:Genes, Regulator; D009865:Oocytes; D011061:Poly A / Q000235:genetics*; D012323:RNA Processing, Post-Transcriptional; D012333:RNA, Messenger / Q000235:genetics*; D012367:RNA, Viral / Q000235:genetics; D013539:Simian virus 40 / Q000235:genetics; D014982:Xenopus laevis
chemical_list: D012333:RNA, Messenger; D012367:RNA, Viral; D011061:Poly A