title: [Paradoxical hyperglucagonemia after oral administration of glucose in diabetic dogs. Impact of the cholinergic nervous system].
abstract: Alloxan diabetic dogs with insulin deficiency showed a transient but significant rise in glucagon levels after oral glucose load (1 g/kg). Pretreatment with atropine sulfate (0.2 mg/kg intravenously) totally suppressed this increase. So, the transient paradoxical rise of glucagon level observed in diabetic dogs after glucose intake is under cholinergic control.
authors.affiliation: Faculté de Médecine, UA 599 du CNRS, Montpellier.
authors.forename: D
authors.initials: D
authors.lastname: Hillaire-Buys
authors.forename: G
authors.initials: G
authors.lastname: Ribes
authors.forename: R
authors.initials: R
authors.lastname: Gross
authors.forename: M M
authors.initials: MM
authors.lastname: Loubatières-Mariani
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D002799:Cholinergic Fibers / Q000502:physiology*; D003921:Diabetes Mellitus, Experimental / Q000097:blood*; D004285:Dogs; D005934:Glucagon / Q000097:blood*; D005947:Glucose / Q000008:administration & dosage*; D007275:Injections, Intravenous; D007328:Insulin / Q000097:blood
chemical_list: D001786:Blood Glucose; D007328:Insulin; D005934:Glucagon; D005947:Glucose
vernacular_title: Hyperglucagonémie paradoxale après administration orale de glucose chez le chien diabétique. Implication du système nerveux cholinergique.