title: Treatment of severe renovascular hypertension by percutaneous transluminal renal angioplasty in patients with solitary functioning kidney. Effects on blood pressure and renal function.
abstract: In this study the effects of percutaneous transluminal renal angioplasty on blood pressure and renal function were studied in 9 hypertensive patients with stenosis of the main artery of a solitary functioning kidney. The outcome of the percutaneous dilatation of the renal artery stenosis, and the effects on blood pressure and renal function were evaluated for a mean period of 16.4 +/- 2.13 (SE) months (ranging from 3 to 65 months). A successful dilatation of the renal artery stenosis was shown in all the patients by the aortography performed 1 h after the procedure. At the discharge (7.8 +/- 0.9 days after dilatation), blood pressure was 'cured' in 2 patients and 'improved' in the remaining patients; renal function was improved in all patients who had reduced renal function. At the last follow-up, no restenosis was found in patients who repeated the follow-up angiography; blood pressure was 'cured' in 3 patients and 'improved' in 6 patients, and renal function appeared steadly improved. In contrast with other reports, our results demonstrate that percutaneous renal angioplasty is a safe and effective procedure and should be attempted before considering surgical intervention in patients with artery stenosis of a solitary functioning kidney.
authors.affiliation: Department of Nephrology, Second Faculty of Medicine, Naples, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Russo
authors.forename: V
authors.initials: V
authors.lastname: Iaccarino
authors.forename: G
authors.initials: G
authors.lastname: Conte
authors.forename: G
authors.initials: G
authors.lastname: Fuiano
authors.forename: R
authors.initials: R
authors.lastname: Niola
authors.forename: A
authors.initials: A
authors.lastname: Testa
authors.forename: P
authors.initials: P
authors.lastname: Mazzone
authors.forename: V E
authors.initials: VE
authors.lastname: Andreucci
mesh_terms: D000328:Adult; D000368:Aged; D000800:Angioplasty, Balloon; D001794:Blood Pressure; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006978:Hypertension, Renovascular / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012077:Renal Artery / Q000503:physiopathology