title: [Comparative study of transcutaneous oxygen pressure and laser- Doppler flow in the feet of 15 healthy subjects].
abstract: Measurement of TcPO2 in arterial diseased patient is a reliable and reproductible method for evaluation in stages III and IV of the degree of tissue ischemia which can serve to establish the viable prognosis of the limb. One of the disadvantages of this technique is the relatively long time taken. By contrast the Doppler-laser, a more recently introduced technique, can be used to measure superficial cutaneous flow. One of its advantages is the rapidity of its instantaneous measurements. Before testing this technique in arterial disease sufferers it was felt to be of interest to determine the possible existence in the healthy subject of a correlation between TcPO2 and laser-Doppler flow. The study involved 15 healty subjects, 8 men and 7 women, with a mean age of 24.2 years. TcPO2 and laser-Doppler measurements were carried out in the fore-foot at 38 degrees and 44 degrees, under basal conditions and then after ischemia each time for 5 minutes, finally followed by a 10-minute 100% hyperoxia test. There was only a slight correlation at 38 degrees between the two methods and no correlation was found at 44 degrees. With oxygen therapy TcPO2 increased considerably and there was a nonsignificant decrease in laser-Doppler flow. In total, the two methods did not truly explore the same microcirculatory data and clinical studies would appear necessary to determine whether laser-Doppler flow measurements in the arterial disease patient may prove to be as useful as those of TcPO2.
authors.affiliation: Clinique médicale A, Hôpital E.-Herriot, Lyon.
authors.forename: R
authors.initials: R
authors.lastname: Nove-Josserand
authors.forename: J
authors.initials: J
authors.lastname: Ninet
authors.forename: P
authors.initials: P
authors.lastname: Bachet
mesh_terms: D000328:Adult; D001785:Blood Gas Monitoring, Transcutaneous; D005260:Female; D005528:Foot / Q000098:blood supply*; D006801:Humans; D007834:Lasers; D008297:Male; D010100:Oxygen / Q000097:blood*; D012039:Regional Blood Flow; D012212:Rheology; D013696:Temperature
chemical_list: D010100:Oxygen
vernacular_title: Etude comparative de la pression d'oxygène transcutanée et du flux laser-Doppler au niveau du pied chez 15 sujets sains.