Sensory symptoms in Parkinson's disease and the opioid system.
Primary sensory symptoms not related to somatic disease, are often experienced by patients with Parkinson's disease. These subjective sensations may either accompany or precede the motor disorder. This paper provides evidence supporting a role for the endogenous opioid system in the pathogenesis of sensory symptoms in Parkinson's disease.
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D001479:Basal Ganglia / Q000503:physiopathology; D003342:Corpus Striatum / Q000503:physiopathology; D004723:Endorphins / Q000502:physiology*; D004744:Enkephalin, Methionine / Q000032:analysis; D006801:Humans; D010300:Parkinson Disease / Q000503:physiopathology*; D011957:Receptors, Opioid / Q000032:analysis; D012677:Sensation / Q000502:physiology*; D013378:Substantia Nigra / Q000503:physiopathology
D004723:Endorphins; D011957:Receptors, Opioid; D004744:Enkephalin, Methionine