Excess body fat distribution and glucose homeostasis in obese Arab women.
The relationship of body fat distribution to glucose intolerance and non-insulin-dependent diabetes mellitus in Arab women was studied in 102 obese non-diabetic and 40 obese women with diabetes. The obese women underwent a glucose tolerance test. Linear regression analysis revealed a significant correlation between the waist/hip ratio and the plasma glucose concentration at 120 min. When divided into two groups according to the median of their waist/hip ratio (0.815), obese women without history of diabetes but with high waist/hip ratio (0.86 +/- 0.07, mean +/- SD) had significantly higher prevalence of glucose intolerance and of diabetes mellitus than those with the low ratio (0.78 +/- 0.03, chi 2 = 9.32, p less than 0.001). The highest ratio (0.89 +/- 0.06) was observed in the obese women with known diabetes mellitus.
Emara
M
M
Department of Medicine and Community Medicine, Faculty of Medicine, Kuwait University, Safat.
Abdella
N
N
Luqman
W
W
Senthilselvan
A
A
Salman
A
A
Fenech
F F
FF
D000273:Adipose Tissue / Q000502:physiology / Q000503:physiopathology*; D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D001823:Body Composition; D003920:Diabetes Mellitus / Q000503:physiopathology*; D005260:Female; D006706:Homeostasis; D006801:Humans; D007730:Kuwait; D009765:Obesity / Q000503:physiopathology*; D012016:Reference Values
D001786:Blood Glucose