Immunoglobulin G antibodies to lymphadenopathy-associated virus in differently treated French and Belgian hemophiliacs.
Immunoglobulin G antibodies to lymphadenopathy-associated virus have been detected in two groups of French hemophiliacs and in one group of Belgian hemophiliacs, whose mode of treatment differed. Seropositivity was more frequent (58.9%) in patients heavily transfused with blood products of French and foreign origin than in less frequently transfused persons (10.3%). The Belgian group, treated only with local products, showed the lowest frequency of seropositivity (3.4%). In healthy French controls, 1 of 330 had antibody to the virus. The results indicate transmission of lymphadenopathy-associated virus via blood-derived products.
Rouzioux
C
C
Brun-Vezinet
F
F
Couroucé
A M
AM
Gazengel
C
C
Vergoz
D
D
Desmyter
J
J
Vermylen
J
J
Vermylen
C
C
Klatzmann
D
D
Geroldi
D
D
D000914:Antibodies, Viral / Q000032:analysis*; D001530:Belgium; D017977:Deltaretrovirus / Q000276:immunology*; D005164:Factor IX / Q000627:therapeutic use; D005169:Factor VIII / Q000627:therapeutic use; D005602:France; D006467:Hemophilia A / Q000628:therapy*; D002836:Hemophilia B / Q000276:immunology / Q000628:therapy; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D008297:Male; D012192:Retroviridae Infections / Q000453:epidemiology*; D012698:Serologic Tests
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D005169:Factor VIII; D005164:Factor IX