Reversal of tropicamide-induced mydriasis by thymoxamine eye drops.
In a study in 12 healthy volunteers, local instillation of thymoxamine eye drops (0.5%), completely reversed the mydriasis produced by tropicamide (0.5%), but only incompletely that by tropicamide (1.0%). The difference between these effects was statistically significant (p less than 0.025). The thymoxamine eye drops were well tolerated.
McKinna
H
H
Department of Optometry and Visual Science, City University, London, England.
Stewart-Jones
J H
JH
Edgar
D F
DF
Turner
P
P
D000328:Adult; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D013948:Moxisylyte / Q000008:administration & dosage / Q000494:pharmacology*; D011680:Pupil / Q000187:drug effects*; D011725:Pyridines / Q000494:pharmacology*; D011897:Random Allocation; D014331:Tropicamide / Q000494:pharmacology*
D011725:Pyridines; D014331:Tropicamide; D013948:Moxisylyte