Cyclosporine A acts as a potent co-stimulator in up-regulation of IgE antibody synthesis and expression of Fc receptor for IgE--a unifying hypothesis of the cellular mechanisms of cyclosporine A.
Chen
S S
SS
Institute of Pathology, Case Western Reserve University, Cleveland, OH 44106.
D000276:Adjuvants, Immunologic; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D001402:B-Lymphocytes / Q000187:drug effects*; D003524:Cyclosporins / Q000494:pharmacology*; D004136:Dinitrobenzenes / Q000276:immunology; D006825:Hybridomas; D007073:Immunoglobulin E / Q000096:biosynthesis*; D007074:Immunoglobulin G / Q000096:biosynthesis; D007165:Immunosuppression Therapy; D051379:Mice; D011961:Receptors, Fc / Q000378:metabolism*; D017455:Receptors, IgE
D000276:Adjuvants, Immunologic; D003524:Cyclosporins; D004136:Dinitrobenzenes; D007074:Immunoglobulin G; D011961:Receptors, Fc; D017455:Receptors, IgE; D007073:Immunoglobulin E