[Comparative evaluation of the cardiotropic effect of broncholytic agents].
The cardiotropic effect of broncholytic agents of different groups used for treatment of bronchial asthma was analyzed by using the method of determination of isoenzyme of MB creatine phosphokinase (CPK) and total CPK in the blood of the patients. A total of 125 biochemical assays on determination of CPK in the blood of the patients were made. The cardiotropic effects of three agents (adrenaline, novodrin, Berodual) were studied. Adrenomimetics adrenaline and isodrin (novodrin) were shown to increase significantly CPK activity. A combined agent Berodual insignificantly increased the activity of MB isoenzyme of CPK.
Orlov
L L
LL
Shilov
A M
AM
Klusova
E V
EV
Borisov
V G
VG
Anikina
E V
EV
D001249:Asthma / Q000188:drug therapy / Q000201:enzymology; D001993:Bronchodilator Agents / Q000627:therapeutic use*; D002317:Cardiovascular Agents; D003402:Creatine Kinase / Q000097:blood; D004338:Drug Combinations / Q000627:therapeutic use; D004341:Drug Evaluation; D004837:Epinephrine / Q000627:therapeutic use; D005280:Fenoterol / Q000627:therapeutic use; D006801:Humans; D009241:Ipratropium / Q000627:therapeutic use; D007527:Isoenzymes; D007545:Isoproterenol / Q000627:therapeutic use; D013268:Stimulation, Chemical; D013997:Time Factors
D001993:Bronchodilator Agents; D002317:Cardiovascular Agents; D004338:Drug Combinations; D007527:Isoenzymes; C030809:fenoterol, ipratropium drug combination; D005280:Fenoterol; D003402:Creatine Kinase; D009241:Ipratropium; D007545:Isoproterenol; D004837:Epinephrine
Sravnitel'naia otsenka kardiotropnogo éffekta bronkholiticheskikh sredstv.