[Long-term results of chymopapain nucleolysis].
The retrospective study of the first 67 patients treated by chemonucleolysis, since December 1980, shows a good overall result, in 69 p. cent of the cases (40 patients) and a failure in 31 p. cent of the cases (18 patients), with a 42 months follow-up. The radiculalgia is cured or quite improved in one month in 90 p. cent of the cases and in 2 years in 88 p. cent. Lumbalgia is absent or moderate after 1 month in 58 p. cent of the cases and after 2 years in 81 p. cent. It persists, most of the time, in women, and this is statistically significant. 15 immediate failures and 3 recurrent sciaticas at the same level are noticed after a 22 months free interval. The possibility of severe complications requires a perfect technique and well-defined indications. The study confirms the good results of nucleolysis with a 42 months follow-up.
Cormier
C
C
Service de Rhumatologie "A", Hôpital Cochin, Paris.
Menkès
C J
CJ
Chevrot
A
A
Amor
B
B
D000328:Adult; D001416:Back Pain / Q000188:drug therapy; D002917:Chymopapain / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007404:Intervertebral Disc Chemolysis; D007405:Intervertebral Disc Displacement / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D012585:Sciatica / Q000188:drug therapy
D002917:Chymopapain
Résultats à long terme de la nucléolyse à la chymopapaïne.