title: Intraperitoneal teicoplanin in the treatment of peritonitis associated with continuous ambulatory peritoneal dialysis.
abstract: The efficacy of teicoplanin in the treatment of peritonitis in patients undergoing continuous ambulatory peritoneal dialysis (CAPD) was evaluated in a randomised comparison with vancomycin. The dosage regimen used was 50 mg of vancomycin or teicoplanin per 2 1 bag of dialysate for 48 h followed by 25 mg per bag for a further five days. Twelve episodes of peritonitis were studied. There was no significant difference in the bacteriological or clinical cure rates of either antibiotic.
authors.affiliation: Department of Medical Microbiology, Withington Hospital, Manchester, UK.
authors.forename: J A
authors.initials: JA
authors.lastname: Bowley
authors.forename: S J
authors.initials: SJ
authors.lastname: Pickering
authors.forename: A J
authors.initials: AJ
authors.lastname: Scantlebury
authors.forename: P
authors.initials: P
authors.lastname: Ackrill
authors.forename: D M
authors.initials: DM
authors.lastname: Jones
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006020:Glycopeptides / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use; D006801:Humans; D007274:Injections, Intraperitoneal; D008826:Microbial Sensitivity Tests; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*; D010538:Peritonitis / Q000188:drug therapy* / Q000209:etiology / Q000382:microbiology; D011897:Random Allocation; D017334:Teicoplanin; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D006020:Glycopeptides; D017334:Teicoplanin; D014640:Vancomycin