[Quantitative assessment of the blood supply to the focus of myocardial ischemia in dogs in pharmacological research].
The method of quantitative evaluation of blood supply of ischemic myocardial focus was suggested, it consists in measuring the venous blood outflow from the ischemic area with the help of ultrasonic technique. In experiments on anaesthetized dogs with coronary artery occlusion the rate of blood flow and dynamics of its changes in the ischemic focus were determined. It was shown that sodium oxybutyrate improves the blood supply of myocardial ischemic area.
Matsievskiĭ
D D
DD
Lyskovtsev
V V
VV
Grigor'eva
E K
EK
Zbrizher
E A
EA
Chichkanov
G G
GG
D000818:Animals; D003326:Coronary Circulation / Q000187:drug effects*; D003327:Coronary Disease / Q000188:drug therapy* / Q000503:physiopathology; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D012212:Rheology; D012978:Sodium Oxybate / Q000627:therapeutic use; D013997:Time Factors; D014159:Transducers
D012978:Sodium Oxybate
Kolichestvennaia otsenka krovosnabzheniia ochaga ishemii miokarda u sobak v farmakologicheskikh issledovaniiakh.