title: Thallium-technetium subtraction scintigraphy as an aid to parathyroid surgery.
abstract: We describe the application of thallium-technetium subtraction scintigraphy in nine patients with failed previous parathyroid surgery or with tertiary hyperparathyroidism due to chronic renal failure. The technique successfully located all adenomas, but only 45% of hyperplastic glands. The series included three abnormal glands located retrosternally. The technique appeared to be more useful in patients with primary hyperparathyroidism than in tertiary hyperparathyroidism, possibly related to differences in gland mass. We conclude that this method of scintigraphy is a valuable adjunct to the management of patients with parathyroid disorders, particularly those requiring revision surgery.
authors.forename: R C
authors.initials: RC
authors.lastname: Percival
authors.forename: G M
authors.initials: GM
authors.lastname: Blake
authors.forename: G H
authors.initials: GH
authors.lastname: Urwin
authors.forename: J L
authors.initials: JL
authors.lastname: Williams
authors.forename: J A
authors.initials: JA
authors.lastname: Kanis
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging; D006801:Humans; D006961:Hyperparathyroidism / Q000000981:diagnostic imaging; D006965:Hyperplasia / Q000000981:diagnostic imaging; D010280:Parathyroid Glands / Q000000981:diagnostic imaging* / Q000601:surgery; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging; D011868:Radioisotopes; D011877:Radionuclide Imaging; D013670:Sodium Pertechnetate Tc 99m; D013382:Subtraction Technique; D013793:Thallium
chemical_list: D011868:Radioisotopes; C027549:thallium chloride; D013670:Sodium Pertechnetate Tc 99m; D013793:Thallium