title: DNA gyrase and its complexes with DNA: direct observation by electron microscopy.
abstract: Electron microscopy of DNA gyrase holoenzyme, of gyrase A subunits, and of the complexes of both species with DNA enables us to deduce the relative locations of subunits in the holoenzyme and to indicate a plausible path for DNA complexed with gyrase. The structural results are discussed in terms of certain models for directional DNA strand transport.
authors.forename: T
authors.initials: T
authors.lastname: Kirchhausen
authors.forename: J C
authors.initials: JC
authors.lastname: Wang
authors.forename: S C
authors.initials: SC
authors.lastname: Harrison
mesh_terms: D001665:Binding Sites; D003201:Computers; D004250:DNA Topoisomerases, Type II / Q000378:metabolism; D004269:DNA, Bacterial / Q000378:metabolism*; D008837:Micrococcus / Q000201:enzymology; D008854:Microscopy, Electron; D008958:Models, Molecular; D011487:Protein Conformation
chemical_list: D004269:DNA, Bacterial; D004250:DNA Topoisomerases, Type II