Oxytocin improves male copulatory performance in rats.
The role of oxytocin in male copulatory performance was reexamined in rats. Adult male rats were trained seven times for copulatory behavior, at weekly intervals. Oxytocin, either intraperitoneally injected (200 ng/rat) or intracerebroventricularly infused (1 ng/rat in 4 microliter saline) 60 and 5 min, respectively, before the eighth test, significantly shortened both the ejaculation latency and the postejaculatory interval. The intracerebroventricular infusion of saline alone (4 microliter/rat) had no effect at all.
Arletti
R
R
Bazzani
C
C
Castelli
M
M
Bertolini
A
A
D000818:Animals; D002490:Central Nervous System / Q000502:physiology; D003307:Copulation / Q000187:drug effects* / Q000502:physiology; D004542:Ejaculation / Q000187:drug effects; D007276:Injections, Intraventricular; D008297:Male; D010121:Oxytocin / Q000494:pharmacology* / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D011930:Reaction Time / Q000187:drug effects; D009435:Synaptic Transmission
D010121:Oxytocin