[Effect of vitamin A deficiency on ATPase activity and the transport functions of erythrocyte membranes].
Influence of vitamin A deficiency on ATPase activity in erythrocytes was studied experimentally. It was shown that activity of Mg2+, Na+, K+-ATPase increased, while that of Na+, K+-ATPase decreased under such conditions. The assay of K+ and Na+ in erythrocytes and plasma revealed diminished K+ content in erythrocytes and its elevated level in plasma, Na+ concentration in erythrocytes rose. The author considers that disorders of protein biosynthesis (at the level of translation) in hypovitaminosis A are responsible for the results obtained.
Cherviak
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MN
D000251:Adenosine Triphosphatases / Q000097:blood*; D000818:Animals; D001692:Biological Transport; D002908:Chronic Disease; D004734:Energy Metabolism; D004910:Erythrocyte Membrane / Q000378:metabolism*; D008297:Male; D011188:Potassium / Q000097:blood; D051381:Rats; D011919:Rats, Inbred Strains; D012964:Sodium / Q000097:blood; D014801:Vitamin A / Q000008:administration & dosage; D014802:Vitamin A Deficiency / Q000201:enzymology*
D014801:Vitamin A; D012964:Sodium; D000251:Adenosine Triphosphatases; D011188:Potassium
Vliianie nedostatochnosti vitamina A na aktivnost' ATFaz i transportnye funktsii membran éritrotsitov.