Effects of aging on the lipid order and composition of rat adipocyte ghosts.
An analysis of the cholesterol/phospholipid ratio of adipocyte ghosts from rat epididymal fat pads shows a significant increase with age (P less than 0.005). An attempt to correlate these changes with the order of the lipid matrix was made using the stearic acid spin label 2-(3-carboxypropyl)-4, 4-dimethyl-2-tridecyl-3-oxazolidinyloxyl [I(12,3)]. Although order was negatively correlated with temperature in preparations from both 6- and 24-month-old rats, no effect of age could be detected.
Rifkind
J M
JM
Suda
T
T
Wang
J T
JT
Heim
J
J
Roth
G S
GS
D000273:Adipose Tissue / Q000032:analysis*; D000375:Aging; D000818:Animals; D002784:Cholesterol / Q000032:analysis; D004578:Electron Spin Resonance Spectroscopy; D008055:Lipids / Q000032:analysis*; D008297:Male; D010743:Phospholipids / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains
D008055:Lipids; D010743:Phospholipids; D002784:Cholesterol