Antibodies to human adult T cell leukaemia virus type I associated antigens in Swedish leukaemia patients and blood donors.
Antibodies to antigens associated with human T cell leukaemia virus type I (HTLV I) in Swedish adult leukaemia patients and blood donors were sought with a sensitive screening test using membrane antigen prepared from virus producing cells (MA-ELISA). Four persons (one ALL, one AML and two healthy blood donors) out of 483 persons tested reacted in the test. However, they were negative in the more specific anti-p19 and anti-whole virion ELISA tests. The prevalence of sera with definite anti-HTLV I activity seems to be very low in Sweden. The finding of four MA-ELISA positive persons needs further investigation.
Blomberg
J
J
Fäldt
R
R
D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis*; D000954:Antigens, Surface / Q000276:immunology; D000956:Antigens, Viral / Q000276:immunology*; D001782:Blood Donors; D017977:Deltaretrovirus / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007938:Leukemia / Q000276:immunology* / Q000382:microbiology; D008875:Middle Aged
D000914:Antibodies, Viral; D000954:Antigens, Surface; D000956:Antigens, Viral