ATPase activities in kidney basolateral plasma membranes of young and old rats.
The present work studied the turnover rate of (Na+ + K+)-ATPase as well as Mg2+- and Na+- ATPase activities in basolateral plasma membranes from kidney cortex cells of young and old rats. It was found that, as for the homogenates, the turnover rate of the (Na+ + K+)-ATPase was diminished by aging in about 40%. The Mg2+-ATPase activities on the other hand, were similar for the rat kidneys of young and old, in both the homogenates as well as the basolateral plasma membrane fractions.
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D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000375:Aging; D000818:Animals; D017301:Ca(2+) Mg(2+)-ATPase; D002462:Cell Membrane / Q000201:enzymology; D007668:Kidney / Q000201:enzymology*; D008297:Male; D010042:Ouabain / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism
D010042:Ouabain; D000251:Adenosine Triphosphatases; D017301:Ca(2+) Mg(2+)-ATPase; D000254:Sodium-Potassium-Exchanging ATPase