Helicopter transport of patients during acute myocardial infarction.
Initial experience with a regional system of emergency helicopter transport of patients with acute myocardial infarction (AMI) referred for emergent cardiac catheterization and percutaneous transluminal coronary angioplasty (PTCA) is described. Two hundred fifty patients with AMI were transported from within a 150-mile radius to Duke University Medical Center over a 15-month period. All patients were within 12 hours of onset of symptoms. Thrombolytic therapy was administered to 240 (96%) patients (72% before or in-flight). The time to administration of thrombolytic therapy ranged from 30 to 120 minutes (median 180), while the time to arrival in the interventional catheterization laboratory ranged from 105 to 815 minutes (median 300). The flight time was 12 to 77 minutes (median 31). Most patients had 1- or 2-vessel coronary artery disease; the baseline ejection fraction ranged from 27 to 70% (median 42). Transient hypotension was the most common complication both pre-flight and in-flight. Third-degree atrioventricular block and nonsustained ventricular tachycardia were the next most common complications. Ventricular fibrillation or sustained ventricular tachycardia occurred before takeoff in 38 patients (15%). No patients had ventricular fibrillation, asystole or respiratory arrest during transport. Fluid boluses for hypotension were the most common intervention. Five patients required cardiopulmonary resuscitation in-flight; 3 before lift-off and 2 required a brief period of cardiopulmonary resuscitation during sustained ventricular tachycardia. Fourteen patients had pressor therapy, military antishock trousers or both to maintain adequate blood pressure. Neither cardioversion, defibrillation nor intubation were performed in-flight. Thus, inflight complications are infrequent and can be managed en route to an intervention center.(ABSTRACT TRUNCATED AT 250 WORDS)
Bellinger
R L
RL
Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.
Califf
R M
RM
Mark
D B
DB
Weber
R A
RA
Collins
P
P
Stone
J
J
Phillips
H R
HR
German
L
L
Stack
R S
RS
D000401:Aircraft; D000800:Angioplasty, Balloon; D006328:Cardiac Catheterization; D004630:Emergencies; D006327:Heart Block / Q000209:etiology; D006801:Humans; D007022:Hypotension / Q000209:etiology; D009203:Myocardial Infarction / Q000150:complications / Q000628:therapy; D009657:North Carolina; D013300:Streptokinase / Q000627:therapeutic use; D013610:Tachycardia / Q000209:etiology; D013997:Time Factors; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D014187:Transportation of Patients
D013300:Streptokinase; D010959:Tissue Plasminogen Activator