[Aspects of the mediator nature of the effect of delta-9-tetrahydrocannabinol on evoked potentials of the cerebral cortex].
It has been shown on cats with the method of the conditional defensive reflexes and parallel recording of the bioelectric activity that the serotonin-negative and dopamine-positive substances restore the similarity of the amplitude-temporary parameters of evoked potentials in the visual, associative and the second comatosencory fields of the brain cortex, disturbed by delta-9-tetrahydrocannabinol injection. It has been also demonstrated that the serotoninergic substances influence the action of delta-9-tetrahydrocannabinol both on the early and late waves of evoked potentials whereas the dopaminergic substances influence the drug action only on the late waves.
Barkov
N K
NK
Machula
A I
AI
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects / Q000502:physiology; D002415:Cats; D002540:Cerebral Cortex / Q000187:drug effects* / Q000502:physiology; D003214:Conditioning, Classical / Q000187:drug effects / Q000502:physiology; D013759:Dronabinol / Q000494:pharmacology*; D004347:Drug Interactions; D005071:Evoked Potentials / Q000187:drug effects; D011941:Receptors, Adrenergic / Q000187:drug effects; D011954:Receptors, Dopamine / Q000187:drug effects; D011985:Receptors, Serotonin / Q000187:drug effects
D011941:Receptors, Adrenergic; D011954:Receptors, Dopamine; D011985:Receptors, Serotonin; D013759:Dronabinol
Nekotorye aspekty mediatornoĭ prirody vliianiia del'ta-9-tetragidrokanabinola na vyzvannye potentsialy kory golovnogo mozga.