title: DNA polymorphism of the major histocompatibility class I genes and their association with serologically defined haplotypes.
abstract: DNA of unrelated persons as well as members of families that were totally or partially homozygous or completely heterozygous on the loci of the major histocompatibility class I genes has been isolated from peripheral blood lymphocytes and blot hybridized with the class I pseudogene pHLA 12.4 probe. The autoradiographic DNA patterns were discussed and compared with well-defined serological features. Positive associations with serologically typed alleles had been demonstrated for HLA-A1,11; -A2; -A3; -B7; -B14; -B35; -Bw41; and -Cw5.
authors.forename: A J
authors.initials: AJ
authors.lastname: Driesel
authors.forename: K
authors.initials: K
authors.lastname: Römer
authors.forename: F
authors.initials: F
authors.lastname: Schunter
authors.forename: M D
authors.initials: MD
authors.lastname: Laryea
authors.forename: E M
authors.initials: EM
authors.lastname: Schneider
authors.forename: P
authors.initials: P
authors.lastname: Wernet
authors.forename: J
authors.initials: J
authors.lastname: Henke
authors.forename: M
authors.initials: M
authors.lastname: Basler
authors.forename: J
authors.initials: J
authors.lastname: Kömpf
mesh_terms: D000483:Alleles; D004247:DNA / Q000302:isolation & purification*; D004262:DNA Restriction Enzymes; D005802:Genes, MHC Class II; D008040:Genetic Linkage; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D008214:Lymphocytes / Q000276:immunology*; D008285:Major Histocompatibility Complex; D009693:Nucleic Acid Hybridization; D011110:Polymorphism, Genetic
chemical_list: D004247:DNA; D004262:DNA Restriction Enzymes