title: [Specific binding of 3H-naloxone with isolated rat enterocytes].
abstract: Specific 3H-naloxone binding with isolated rat enterocytes has been demonstrated. This binding was selectively inhibited by different opiates and proved to be irreversible, temperature-dependent and sodium azide-sensitive. The presence of naloxone binding sites on enterocytes indicates a possible involvement of opiates in the regulation of enterocyte functions.
authors.forename: K N
authors.initials: KN
authors.lastname: Iarygin
authors.forename: D D
authors.initials: DD
authors.lastname: Sviridov
authors.forename: A G
authors.initials: AG
authors.lastname: Shitin
authors.forename: V A
authors.initials: VA
authors.lastname: Vinogradov
authors.forename: M I
authors.initials: MI
authors.lastname: Titov
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D066298:In Vitro Techniques; D007421:Intestine, Small / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D007700:Kinetics; D008024:Ligands; D008297:Male; D009270:Naloxone / Q000378:metabolism*; D009294:Narcotics / Q000494:pharmacology; D051381:Rats; D011957:Receptors, Opioid / Q000187:drug effects / Q000378:metabolism*; D014316:Tritium
chemical_list: D008024:Ligands; D009294:Narcotics; D011957:Receptors, Opioid; C034565:naloxone receptor; D014316:Tritium; D009270:Naloxone
vernacular_title: Spetsificheskoe sviazyvanie 3H-naloksona s izolirovannymi énterotsitami krys.