NMR parameters of local anesthetics as biological markers of the cell-virus interactions.
The selective proton NMR relaxation rates were measured in the system made by the local anesthetic procaine, human erythrocytes and the hemagglutinating Echo virus type 11. The NMR technique provided a very good tool for using drugs firmly bound to receptor membranes as biological "markers" of the virus-cell interaction.
Valensin
P E
PE
Bianchi-Bandinelli
M L
ML
di Cairano
M L
ML
Gaggelli
E
E
Valensin
G
G
D000327:Adsorption; D003078:Colchicine / Q000494:pharmacology; D003208:Concanavalin A / Q000494:pharmacology; D015638:Cytochalasin D; D003572:Cytochalasins / Q000494:pharmacology; D029822:Enterovirus B, Human / Q000378:metabolism*; D004910:Erythrocyte Membrane / Q000378:metabolism / Q000382:microbiology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D011343:Procaine / Q000378:metabolism*; D011522:Protons; D011991:Receptors, Virus / Q000378:metabolism*
D003572:Cytochalasins; D011522:Protons; D011991:Receptors, Virus; D003208:Concanavalin A; D015638:Cytochalasin D; D011343:Procaine; D003078:Colchicine