[Enzymatic activity of the microsomal fraction of the mucosa of the small intestine in guinea pigs with vitamin D and C deficiencies].
The influence of vitamin D and C deficiency on the kinetic parameters of sucrase and alkali phosphatase activities was studied in the microsomal fraction of the small intestinal mucosa of guinea pigs. It was found that Km values for these enzymes did not depend on the animal providing with these vitamins. Deficiency of one of these vitamins did not influence sucrase activity, however, simultaneous elimination of vitamins D and C resulted in the activity rise by 92%. Alkali phosphatase and Ca-ATPase activities proved to be similarly dependent on providing with vitamin D in the presence of vitamin C in the ration, while in the absence of vitamin C this dependence was not observed.
Kodentsova
V M
VM
Klimova
O A
OA
Sokol'nikov
A A
AA
Kha
K M
KM
Sergeev
I N
IN
D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D001205:Ascorbic Acid / Q000008:administration & dosage; D001206:Ascorbic Acid Deficiency / Q000201:enzymology*; D017301:Ca(2+) Mg(2+)-ATPase / Q000378:metabolism; D000252:Calcium-Transporting ATPases / Q000378:metabolism; D006168:Guinea Pigs; D007413:Intestinal Mucosa / Q000201:enzymology*; D007421:Intestine, Small / Q000201:enzymology*; D008297:Male; D008861:Microsomes / Q000201:enzymology*; D013393:Sucrase / Q000378:metabolism; D014807:Vitamin D / Q000008:administration & dosage; D014808:Vitamin D Deficiency / Q000201:enzymology*
D014807:Vitamin D; D000469:Alkaline Phosphatase; D013393:Sucrase; D017301:Ca(2+) Mg(2+)-ATPase; D000252:Calcium-Transporting ATPases; D001205:Ascorbic Acid
Aktivnost' nekotorykh fermentov mikrosomal'noĭ fraktsii slizistoĭ obolochki tonkoĭ kishki morskikh svinok pri nedostatochnosti vitaminov D i C.