title: Evolution of tumours and the impact of molecular oncology.
abstract: It is generally accepted that tumours arise through the accumulation of several changes affecting the control of cell growth. Recent advances in molecular biology have made it possible to define some of these changes in molecular terms and to trace the steps by which certain tumours evolve.
authors.forename: G
authors.initials: G
authors.lastname: Klein
authors.forename: E
authors.initials: E
authors.lastname: Klein
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000502:physiology; D002051:Burkitt Lymphoma / Q000235:genetics; D018288:Carcinoma, Small Cell / Q000235:genetics; D002472:Cell Transformation, Viral; D002872:Chromosome Deletion; D002999:Clone Cells / Q000473:pathology; D005786:Gene Expression Regulation; D004854:Herpesvirus 4, Human; D006801:Humans; D007136:Immunoglobulins / Q000235:genetics; D008175:Lung Neoplasms / Q000235:genetics; D009369:Neoplasms / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D009857:Oncogenes; D010954:Plasmacytoma / Q000235:genetics; D014178:Translocation, Genetic
chemical_list: D007136:Immunoglobulins