title: Effect of cGMP and cations on the permeability of cattle retinal disks.
abstract: Guanosine 3',5'-monophosphate and Na or Ca ions affect the transmembrane movements of the same pool of intradiskal ions. Extradiskal Na ions activate the efflux of intradiskal Na ions. Extradiskal Ca ions activate the efflux of intradiskal Rb ions. Na and Ca ions activate Na/Ca or Ca/Ca exchange, as previously described. cGMP activates a membrane permeability for all the cations tested, as previously described. The reciprocal relations between cGMP and the other pathways for ion movements through disk membranes are systematically examined. Some analogies between the cGMP-activated permeability of the disk membranes and the light-sensitive conductance of the rod plasma outer membrane are discussed.
authors.forename: A
authors.initials: A
authors.lastname: Caretta
mesh_terms: D000818:Animals; D001711:Biotransformation; D002118:Calcium / Q000494:pharmacology; D002412:Cations / Q000494:pharmacology*; D002417:Cattle; D002462:Cell Membrane / Q000378:metabolism; D002463:Cell Membrane Permeability / Q000187:drug effects*; D006152:Cyclic GMP / Q000494:pharmacology*; D004735:Energy Transfer; D008027:Light; D010786:Photoreceptor Cells / Q000378:metabolism*; D012413:Rubidium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism / Q000494:pharmacology
chemical_list: D002412:Cations; D012964:Sodium; D006152:Cyclic GMP; D012413:Rubidium; D002118:Calcium