title: Hepatocellular carcinoma in young, mentally retarded HBsAg carriers without cirrhosis.
abstract: In a Californian institution for the mentally retarded, surveillance by autopsy of all deaths (n = 138) identified three cases of hepatocellular carcinoma. Hepatocellular carcinoma cases occurred in young (mean age = 26 years) male carriers of HBsAg and were not associated with cirrhosis. They were of the nonfibrolamellar oncocytic type and were rapidly fatal. Hepatocellular carcinoma incidence in HBsAg carriers was estimated to be 246 times greater than United States males.
authors.forename: G
authors.initials: G
authors.lastname: Lohiya
authors.forename: H
authors.initials: H
authors.lastname: Pirkle
authors.forename: J
authors.initials: J
authors.lastname: Hoefs
authors.forename: S
authors.initials: S
authors.lastname: Lohiya
authors.forename: V T
authors.initials: VT
authors.lastname: Ngo
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000276:immunology* / Q000473:pathology; D002353:Carrier State / Q000276:immunology*; D006509:Hepatitis B / Q000276:immunology*; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006801:Humans; D008607:Intellectual Disability / Q000276:immunology*; D008103:Liver Cirrhosis; D008113:Liver Neoplasms / Q000276:immunology* / Q000473:pathology; D008297:Male
chemical_list: D006514:Hepatitis B Surface Antigens