Regulation of CDP-diacylglycerol synthase activity in Saccharomyces cerevisiae.
The addition of ethanolamine or choline to inositol-containing growth medium resulted in a reduction of CTP:phosphatidate cytidylyltransferase (CDP-diacylglycerol synthase; EC 2.7.7.41) activity in Saccharomyces cerevisiae. The reduction of activity did not occur in the absence of inositol. CDP-diacylglycerol synthase activity was not regulated in a S. cerevisiae mutant strain (opi1; an inositol biosynthesis regulatory mutant) by the addition of phospholipid precursors to the growth medium.
Homann
M J
MJ
Henry
S A
SA
Carman
G M
GM
D002794:Choline / Q000494:pharmacology; D019856:Ethanolamine; D004983:Ethanolamines / Q000494:pharmacology; D007700:Kinetics; D009713:Nucleotidyltransferases / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000201:enzymology* / Q000254:growth & development; D014316:Tritium
D004983:Ethanolamines; D014316:Tritium; D019856:Ethanolamine; D009713:Nucleotidyltransferases; C022348:phosphatidate cytidylyltransferase; D002794:Choline