Morphometric study of hepatic ultrastructure in alcoholic hepatitis. Veterans Administration Cooperative Study Group on Alcoholic Hepatitis.
We undertook a morphometric analysis of hepatocellular organelles in an attempt to correlate their changes with the clinical stages of patients with alcoholic hepatitis. Although hepatic ultrastructural alterations did not correlate with disease severity, we found significant differences between patient and control groups in the measured parameters of non-organelle cytoplasm, mitochondria, SER, RER, glycogen, and lipid.
Chen
T S
TS
V.A. Medical Center, East Orange, NJ 07019.
Murphy
D P
DP
Marquet
G
G
Chedid
A
A
Mendenhall
C L
CL
Rabin
L
L
D001706:Biopsy; D006801:Humans; D008099:Liver / Q000473:pathology / Q000648:ultrastructure*; D008104:Liver Cirrhosis, Alcoholic / Q000473:pathology*; D008107:Liver Diseases / Q000473:pathology; D008297:Male