title: [Treatment by redilatation and thrombolysis of occlusion occurring during percutaneous coronary angioplasty].
abstract: In patients who develop acute coronary occlusion during or after percutaneous coronary angioplasty, surgery is not mandatory, and other treatments may be considered, namely redilatation and/or thrombolysis. Between June, 1984 and January, 1988 we performed 500 dilatations of coronary arteries, not counting the attempts made in the acute phase of myocardial infarction. Acute coronary occlusion without angiographic image of occlusive dissection occurred in 31 patients (6.2%) and was treated by attempted redilatation and intracoronary thrombolysis. In 10 patients (group A) either the occlusion could not be removed and emergency surgery was tried (5 cases with 2 infarctions and 1 death), or the occlusion was removed but myocardial infarction took place (5 cases). In 21 patients (group B), the occlusion was removed and the outcome was favourable without myocardial infarction. Altogether, myocardial infarction or death occurred in only 8 cases, or 26% of acute occlusions. The clinical and angiographic features of the two groups before and after angioplasty were compared; two of them differentiated group A from group B: (1) unstable angina, 7/10 in group A, 4/21 in group B (p less than 0.01), and (2) degree of stenosis, 93.1% in group A, 78% in group B (p less than 0.01). When coronary occlusion occurs during or after coronary angioplasty and is poorly tolerated with fall in blood pressure, surgery must be contemplated at once, even after recanalization of the vessel and subsidence of ischaemia. In all other cases, treatment with both redilatation and thrombolysis should restore the benefits of angioplasty without myocardial infarction.
authors.affiliation: Service de cardiologie, CHU Pitié-Salpêtrière, Paris.
authors.forename: G
authors.initials: G
authors.lastname: Drobinski
authors.forename: J
authors.initials: J
authors.lastname: Quininha
authors.forename: J P
authors.initials: JP
authors.lastname: Metzger
authors.forename: M
authors.initials: M
authors.lastname: Canny
authors.forename: N
authors.initials: N
authors.lastname: Moussallem
authors.forename: J Y
authors.initials: JY
authors.lastname: Artigou
authors.forename: Y
authors.initials: Y
authors.lastname: Grosgogeat
mesh_terms: D000328:Adult; D000368:Aged; D000800:Angioplasty, Balloon; D017023:Coronary Angiography; D003327:Coronary Disease / Q000628:therapy*; D003328:Coronary Thrombosis / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007269:Injections, Intra-Arterial; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000628:therapy; D012008:Recurrence; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use*
chemical_list: D014568:Urokinase-Type Plasminogen Activator
vernacular_title: Traitement par redilatation et thrombolyse des occlusions survenant lors des angioplasties coronaires percutanées.