Chemotherapy and vitamin E in treatment of Nb rat prostate tumors.
Combination of Vitamin E in a single megadose of 20 units per 200 gram rat and chemotherapy was performed. The results revealed that Vitamin E treatment does indeed reduce Adriamycin toxicity and adds to tumor reduction and decrease metastasis. Vitamin E also enhances the efficacy of Cyclophosphamide, Adriamycin and Methotrexate.
Drago
J R
JR
Department of Surgery, College of Medicine, Ohio State University, Columbus.
Nesbitt
J A
JA
Badalament
R A
RA
Smith
J
J
D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002460:Cell Line; D008297:Male; D011471:Prostatic Neoplasms / Q000188:drug therapy* / Q000473:pathology; D051381:Rats; D014810:Vitamin E / Q000627:therapeutic use*
D000970:Antineoplastic Agents; D014810:Vitamin E