[Influence of mycoplasma on the production of the oncogenic leukemia virus HTLV by HUT-102 T-lymphoblastoid cells].
A suspension culture of human T-lymphoblasts HUT-102 producing type C oncovirus (HTLV) was examined electron microscopically. Control decontaminated HUT-102 cells spontaneously contaminated with M. orale and exogenously infected with M. pneumoniae were examined in ultrathin sections. The variation statistics method demonstrated that in the mycoplasma-infected cells the number of HTLV virions was significantly higher than in control cultures. It is assumed that the increased production of HTLV is due to mycoplasma-induced changes of physico-chemical properties of the cell membrane which facilitate virion budding.
Alymbaeva
D B
DB
Miller
G G
GG
Rakovskaia
I V
IV
Bykovskiĭ
A F
AF
D002460:Cell Line; D017977:Deltaretrovirus / Q000302:isolation & purification*; D006801:Humans; D008854:Microscopy, Electron; D009174:Mycoplasma / Q000472:pathogenicity*; D009175:Mycoplasma Infections / Q000382:microbiology; D009177:Mycoplasma pneumoniae / Q000472:pathogenicity; D012192:Retroviridae Infections / Q000382:microbiology; D013601:T-Lymphocytes / Q000382:microbiology* / Q000648:ultrastructure; D014771:Virion / Q000302:isolation & purification; D014776:Virus Cultivation
Vliianie mikoplazmy na produktsiiu onkogennogo leĭkoznogo virusa HTLV T-limfoblastoidnymi kletkami HUT-102.