[Alpha-hANP-like immunoreactivity in lung cancer].
Specific radioimmunoassay and immunohistochemical method of alpha-human atrial natriuretic polypeptide (alpha-hANP) was established to diagnose one case of large cell lung carcinoma (clear cell carcinoma) proved by pathology. It was found that there was alpha-hANP-like immunoreactivity in the cancer cells at a concentration of 147.5 pg/mg protein. Chromatography analysis showed that alpha-hANP-like immunoreactive materials had multiple molecular forms. The significance of these phenomena remains to be further investigated.
An
S Z
SZ
Beijing University of Medical Sciences.
Wang
J P
JP
Tang
J
J
Xie
C W
CW
Wang
T L
TL
Wu
J
J
Xin
Y L
YL
D000230:Adenocarcinoma / Q000032:analysis*; D009320:Atrial Natriuretic Factor / Q000032:analysis*; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D010446:Peptide Fragments / Q000032:analysis*; D011863:Radioimmunoassay
D010446:Peptide Fragments; D009320:Atrial Natriuretic Factor