title: An EcoRI restriction fragment length polymorphism (RFLP) in the human c-erb A locus.
abstract: An EcoRI restriction fragment length polymorphism (RFLP) was detected in the 3' end of the locus of the c-erb-A proto-oncogene. The frequency of the rarer allele was around 3.0% in a normal population of 107 unrelated individuals. This frequency did not significantly differ in DNA samples from patients with breast tumors or acute leukemias.
authors.forename: D
authors.initials: D
authors.lastname: Mathieu-Mahul
authors.forename: D Q
authors.initials: DQ
authors.lastname: Xu
authors.forename: S
authors.initials: S
authors.lastname: Saule
authors.forename: R
authors.initials: R
authors.lastname: Lidereau
authors.forename: F
authors.initials: F
authors.lastname: Galibert
authors.forename: R
authors.initials: R
authors.lastname: Berger
authors.forename: M
authors.initials: M
authors.lastname: Mauchauffé
authors.forename: C J
authors.initials: CJ
authors.lastname: Larsen
mesh_terms: D001355:Alpharetrovirus / Q000235:genetics*; D001354:Avian Leukosis Virus / Q000235:genetics*; D001943:Breast Neoplasms / Q000235:genetics; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D004262:DNA Restriction Enzymes; D004273:DNA, Neoplasm / Q000235:genetics; D015246:Deoxyribonuclease EcoRI; D005260:Female; D006801:Humans; D007938:Leukemia / Q000235:genetics; D008297:Male; D009693:Nucleic Acid Hybridization; D009857:Oncogenes; D010375:Pedigree; D011110:Polymorphism, Genetic; D000090063:Proto-Oncogene Mas
chemical_list: D004273:DNA, Neoplasm; C000715470:MAS1 protein, human; D000090063:Proto-Oncogene Mas; D004262:DNA Restriction Enzymes; D015246:Deoxyribonuclease EcoRI