[Effect of electron-acceptor compounds on the immunoregulatory mechanisms and ATPase activity of the erythrocyte membranes from patients with inoperable lung cancer].
In 55 inoperable patients with lung cancer the use of tinidizole and metronidazole with X-ray therapy intensified the immunoregulative disbalance, increased the quantity of circulative immune complexes and reduced the Na+K+-ATPase activity of erythrocyte membranes in contrast to the data obtained from patients receiving only X-ray therapy. Thus the data obtained may be the basis for the use of the correcting therapy in inoperable patients with lung cancer.
Pivniuk
V M
VM
Semenchuk
D D
DD
Shkliarskaia
L A
LA
D000251:Adenosine Triphosphatases / Q000097:blood* / Q000528:radiation effects; D003131:Combined Modality Therapy; D004579:Electron Transport; D004910:Erythrocyte Membrane / Q000187:drug effects* / Q000201:enzymology / Q000276:immunology / Q000528:radiation effects; D006801:Humans; D008175:Lung Neoplasms / Q000201:enzymology / Q000276:immunology* / Q000628:therapy; D008795:Metronidazole / Q000627:therapeutic use; D011838:Radiation-Sensitizing Agents / Q000627:therapeutic use*; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology / Q000528:radiation effects; D014011:Tinidazole / Q000627:therapeutic use
D011838:Radiation-Sensitizing Agents; D014011:Tinidazole; D008795:Metronidazole; D000251:Adenosine Triphosphatases
Vliianie élektronaktseptornykh soedineniĭ na immunoreguliatornye mekhanizmy i ATPaznuiu aktivnost' membran éritrotsitov krovi neoperabel'nykh bol'nykh rakom legkogo.