Acute toxicity of iopentol in rodents.
Testing of the intravenous toxicity (LD50) of iopentol in mice and rats showed results comparable to the toxicity of non-ionic monomeric contrast media already in clinical use. Toxicity data suggest that iopentol may be a useful compound for use as an intravascular radiographic contrast medium.
Michelet
A A
AA
Department of Pharmacology and Toxicology, Nycomed As, Oslo, Norway.
Salvesen
S
S
Renaa
T
T
D000208:Acute Disease; D000818:Animals; D003287:Contrast Media / Q000633:toxicity*; D005260:Female; D007472:Iohexol / Q000633:toxicity; D007479:Iopamidol / Q000633:toxicity; D008297:Male; D051379:Mice; D051381:Rats; D011919:Rats, Inbred Strains; D014283:Triiodobenzoic Acids / Q000633:toxicity*
D003287:Contrast Media; D014283:Triiodobenzoic Acids; D007472:Iohexol; C053571:iopentol; D007479:Iopamidol