Comparison of a fenoterol/ipratropium combination with salbutamol from metered dose inhalers in subjects with chronic partially reversible airways obstruction.
We have compared the acute bronchodilator response following salbutamol 200 micrograms and fenoterol 200 micrograms with ipratropium 80 micrograms, from metered dose inhalers in ten subjects with severe partially reversible airflow obstruction. Treatment with the combination resulted in a similar degree of bronchodilation but with a significantly longer duration of action.
Crane
J
J
Department of Medicine, Wellington Medical School.
Gamble
S
S
Purdie
G
G
D000368:Aged; D000420:Albuterol / Q000008:administration & dosage*; D001286:Atropine Derivatives / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005280:Fenoterol / Q000008:administration & dosage*; D006801:Humans; D009241:Ipratropium / Q000008:administration & dosage*; D008173:Lung Diseases, Obstructive / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009330:Nebulizers and Vaporizers
D001286:Atropine Derivatives; D005280:Fenoterol; D009241:Ipratropium; D000420:Albuterol