Pseudotumor cerebri caused by isotretinoin.
A 16-year-old girl treated with isotretinoin at a dosage of 0.7 mg per kg each day experienced severe headaches and impaired night vision two months after the start of therapy. Bilateral papilledema and narrowing of the lateral ventricles of the brain were found. Pseudotumor cerebri and impaired night vision abated when isotretinoin was discontinued and systemic corticosteroids (dexamethasone) were administered.
Roytman
M
M
University of Oklahoma, Oklahoma City.
Frumkin
A
A
Bohn
T G
TG
D000152:Acne Vulgaris / Q000188:drug therapy*; D000293:Adolescent; D005260:Female; D006801:Humans; D015474:Isotretinoin / Q000009:adverse effects* / Q000627:therapeutic use; D009755:Night Blindness / Q000139:chemically induced; D011559:Pseudotumor Cerebri / Q000139:chemically induced*
D015474:Isotretinoin