title: [Myxedematous coma. Prognostic and therapeutic re-evaluation].
abstract: The prognostic factors and therapeutic approaches in myxoedema coma--a rare but serious medical emergency--were re-evaluated from a retrospective study of 10 cases. The immediate respiratory risk can be prevented by referring these patients immediately to an intensive care unit. The patient's cardiovascular status before and after coma determines the prognosis for life and serves as guideline to treatment. Hormone replacement therapy with initial injection of a loading dose of thyroxine seems to improve the prognosis by ensuring rapid recovery of the principal vital functions.
authors.affiliation: Service d'Endocrinologie-Nutrition-Diabétologie et Médecine interne, Hôpital de l'Archet, Nice.
authors.forename: P
authors.initials: P
authors.lastname: Fenichel
authors.forename: M
authors.initials: M
authors.lastname: Zartarian
authors.forename: D
authors.initials: D
authors.lastname: Grimaud
authors.forename: F
authors.initials: F
authors.lastname: Brucker
authors.forename: P
authors.initials: P
authors.lastname: Morand
authors.forename: M
authors.initials: M
authors.lastname: Harter
authors.forename: A
authors.initials: A
authors.lastname: Fredenrich
authors.forename: M
authors.initials: M
authors.lastname: Zartariana
authors.forename: D
authors.initials: D
authors.lastname: Frimaud
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000209:etiology; D003128:Coma / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000209:etiology; D007035:Hypothermia / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009230:Myxedema / Q000150:complications* / Q000188:drug therapy; D011379:Prognosis; D012140:Respiratory Tract Diseases / Q000209:etiology; D012189:Retrospective Studies; D012307:Risk Factors
vernacular_title: Le coma myxoedémateux. Réévaluation pronostique et thérapeutique.