title: Hematoporphyrin derivative photosensitization and cellular fluorescent photoproduct formation.
abstract: A new fluorescence band with an emission maximum at 460 nm was observed in S180 tumour cells and human cancer tissues photosensitized by Y-HPD. This fluorescence was the result of a photochemical reaction involving specific proteins and Y-HPD in the cells.
authors.affiliation: Institute of Biophysics, Academia Sinica, Beijing, China.
authors.forename: E H
authors.initials: EH
authors.lastname: Cao
authors.forename: X J
authors.initials: XJ
authors.lastname: Fan
authors.forename: S J
authors.initials: SJ
authors.lastname: Chi
authors.forename: Y X
authors.initials: YX
authors.lastname: Wang
mesh_terms: D000818:Animals; D001711:Biotransformation; D002467:Cell Nucleus / Q000378:metabolism; D002470:Cell Survival / Q000187:drug effects; D002843:Chromatin / Q000378:metabolism; D003593:Cytoplasm / Q000378:metabolism; D017324:Hematoporphyrin Derivative; D006415:Hematoporphyrins / Q000378:metabolism*; D006801:Humans; D008027:Light; D051379:Mice; D011838:Radiation-Sensitizing Agents / Q000378:metabolism*; D012510:Sarcoma 180 / Q000378:metabolism* / Q000473:pathology; D013050:Spectrometry, Fluorescence; D014407:Tumor Cells, Cultured / Q000166:cytology / Q000378:metabolism*; D014466:Ultraviolet Rays
chemical_list: D002843:Chromatin; D006415:Hematoporphyrins; D011838:Radiation-Sensitizing Agents; D017324:Hematoporphyrin Derivative