[PolyADP-ribosyl polymerase (adenosine diphosphate ribosyl transferase) in bovine crystalline lens; modulation of its activity during aging].
PolyADP-ribose polymerase activities were measured in bovine lens. Activities similar to those in brain were found in the epithelial cells; none activity was detected in the fiber cells. During aging ADP-ribosyl transferase activity of epithelial cells raised, the number of polyADP-ribose chains increased while the average chain length decreased. A possible correlation between ADP-ribosylation and cell proliferation or repair is discussed.
Bizec
J C
JC
Klethi
J
J
Mandel
P
P
D000375:Aging; D000818:Animals; D002417:Cattle; D004260:DNA Repair; D004848:Epithelium / Q000201:enzymology; D007908:Lens, Crystalline / Q000201:enzymology*; D009244:NAD+ Nucleosidase / Q000378:metabolism*; D011065:Poly(ADP-ribose) Polymerases / Q000378:metabolism*
D011065:Poly(ADP-ribose) Polymerases; D009244:NAD+ Nucleosidase
PolyADP-ribosyl polymérase (adénosine diphosphate-ribosyl transférase) du cristallin de bovidés; modulation de son activité au cours du vieillissement.