title: [Experiments to produce an attenuated strain of the transmissible gastroenteritis virus and its use as a live vaccine].
abstract: Serial passages have been performed of a field virus of the transmissive gastroenteritis to obtain an attenuated strain adapted to a permanent cell line of pig kidney, "SPEV". The strain is innocuous for test animals, for pigs of all ages, and for swine during the entire period of pregnancy. It has proved genetically stable. The strain is immunogenic for swine and pigs both under laboratory and under field conditions (in new foci and on stationary farms) and can be used as a live vaccine against transmissive gastroenteritis, either untreated or in a freeze-dried state.
authors.forename: A
authors.initials: A
authors.lastname: Motovski
authors.forename: V
authors.initials: V
authors.lastname: Katevska
authors.forename: P
authors.initials: P
authors.lastname: Belopopska
authors.forename: N
authors.initials: N
authors.lastname: Naĭdenova
authors.forename: E
authors.initials: E
authors.lastname: Veleva
mesh_terms: D000818:Animals; D003332:Coronaviridae / Q000302:isolation & purification*; D004353:Drug Evaluation, Preclinical / Q000662:veterinary; D005260:Female; D005761:Gastroenteritis, Transmissible, of Swine / Q000276:immunology / Q000517:prevention & control; D006168:Guinea Pigs; D011247:Pregnancy; D011817:Rabbits; D013552:Swine / Q000276:immunology; D013997:Time Factors; D005760:Transmissible gastroenteritis virus / Q000276:immunology / Q000302:isolation & purification*; D014613:Vaccines, Attenuated / Q000276:immunology / Q000302:isolation & purification; D014765:Viral Vaccines / Q000276:immunology / Q000302:isolation & purification*; D014776:Virus Cultivation / Q000379:methods
chemical_list: D014613:Vaccines, Attenuated; D014765:Viral Vaccines
vernacular_title: Opiti za polchavane na atenuiran shtam na virusa na transmisivniia gastroenterit i izpolzuvaneto mu kato zhiva vaksina.