title: [Keratosis palmoplantaris diffuse circumscripta (Thost-Unna) with micropenis].
abstract: We report on a 2-year-old boy showing diffuse palmoplantar keratoderma (Thost-Unna's disease) in association with congenital penis hypoplasia. Family history research proved palmoplantar keratoderma autosomally dominant over 5 generations. The boy's 6-month-old brother also shows penis hypoplasia, as yet, however, without signs of palmoplantar keratoderma. So far we are not able to settle the question whether this case represents a clinical entity of its own or merely a chance association of rare symptoms.
authors.affiliation: Universitäts-Hautklinik Köln.
authors.forename: K H
authors.initials: KH
authors.lastname: Kurz
authors.forename: G K
authors.initials: GK
authors.lastname: Steigleder
mesh_terms: D002675:Child, Preschool; D005799:Genes, Dominant; D006801:Humans; D007021:Hypospadias / Q000235:genetics*; D007645:Keratoderma, Palmoplantar / Q000235:genetics*; D008297:Male; D010375:Pedigree
vernacular_title: Keratosis palmoplantaris diffusa circumscripta (Thost-Unna) mit Mikropenis.