Amino acid sequence homology between protein products of oncogenes and hormones (v-myc--gastrin and oxytocin; v-sis--secretin).
Computer comparisons of amino acid sequences from 8 retroviral oncogenes and 26 protein hormones were done with respect to structure similarity and so-called uninterrupted structure similarity. Sequence homology was found between v-myc, the transforming protein of MC29 virus, and human gastrin and oxytocin on the one hand, and between v-sis, the transforming protein of simian sarcoma virus, and secretin on the other.
Korec
E
E
Hlozánek
I
I
Korcová
H
H
Simůnek
J
J
D000595:Amino Acid Sequence; D003201:Computers; D005755:Gastrins / Q000235:genetics; D006728:Hormones / Q000235:genetics* / Q000378:metabolism; D009857:Oncogenes; D010121:Oxytocin / Q000235:genetics; D010802:Phylogeny; D011956:Receptors, Cell Surface / Q000378:metabolism; D012190:Retroviridae / Q000235:genetics*; D012633:Secretin / Q000235:genetics; D014764:Viral Proteins / Q000235:genetics*
D005755:Gastrins; D006728:Hormones; D011956:Receptors, Cell Surface; D014764:Viral Proteins; D012633:Secretin; D010121:Oxytocin