Gentamicin: systemic exposure to a contact allergen.
A case is presented of an allergic dermatitis provoked by intravenous gentamicin in a patient previously sensitized by topical medications. Patch tests confirmed hypersensitivity to gentamicin and neomycin. The nature of reactions to contact allergens given systemically and the nature of cross-reactions between aminoglycoside antibiotics are reviewed.
Ghadially
R
R
Division of Dermatology, University of Toronto.
Ramsay
C A
CA
D000368:Aged; D000369:Aged, 80 and over; D003429:Cross Reactions; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007262:Infusions, Intravenous; D009355:Neomycin / Q000009:adverse effects; D010328:Patch Tests
D005839:Gentamicins; D009355:Neomycin