[Cross-reactivity between parasitic antigens and T lymphocyte surface antigens: a possible host-escape mechanism for Echinococcus multilocularis].
We report an immunocytochemical analysis of E. m. protoscolices obtained in 2 strains of mice (AKR, Balb c) which were experimentally infected. Sections of hepatic and peritoneal lesions and spreading of protoscolices from peritoneal vesicles were analyzed. Five monoclonal antibodies, specific of murine T lymphocyte populations, produced an intense and regular staining of the anterior area of the protoscolices. This immunostaining has not yet been explained; it could bear witness to particular mode of parasite protection against host immunological responses.
Bresson-Hadni
S
S
Service d'Hépatologie, CHU, Besançon.
Liance
M
M
Houin
R
R
Bresson
J L
JL
Lenys
D
D
Miguet
J P
JP
Vuitton
D
D
D000818:Animals; D000911:Antibodies, Monoclonal; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis*; D003429:Cross Reactions; D004446:Echinococcus / Q000276:immunology*; D006790:Host-Parasite Interactions; D007150:Immunohistochemistry; D051379:Mice; D008807:Mice, Inbred BALB C
D000911:Antibodies, Monoclonal; D000945:Antigens, Differentiation, T-Lymphocyte; D000954:Antigens, Surface
Réaction croisée entre antigènes parasitaires et antigènes de surface des lymphocytes T: un mécanisme d'évasion d'Echinococcus multilocularis vis-à-vis de la réponse immune de l'hôte?