Hypersensitivity to Shigella outer membrane proteins in mice.
Mice sensitized with living Sh. flexneri 3a or with outer membrane proteins (OMP) derived from these bacteria showed Arthus and delayed type hypersensitivity (DTH) when injected in the footpad with OMP. The delayed reactivity to OMP was transferable to normal mice by spleen cells obtained from donor animals which were previously sensitized with living bacteria.
Mulczyk
M
M
Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław.
Witkowska
D
D
Mleczko
J
J
D000818:Animals; D001183:Arthus Reaction / Q000209:etiology*; D001425:Bacterial Outer Membrane Proteins / Q000276:immunology / Q000302:isolation & purification; D005260:Female; D006968:Hypersensitivity, Delayed / Q000209:etiology*; D007114:Immunization; D007116:Immunization, Passive; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D012763:Shigella flexneri / Q000276:immunology*
D001425:Bacterial Outer Membrane Proteins