Molecular epidemiology of two US orbiviruses: bluetongue virus and epizootic hemorrhagic disease virus.
The degree of relatedness between 4 US serotypes (10, 11, 13 and 17) of bluetongue (BT) virus (BTV) were determined by both oligonucleotide fingerprint analyses of double-stranded (ds) RNA as well as tryptic peptide analyses of viral coded polypeptides. Similar studies were undertaken using different alternate isolates of particular serotypes as well as 2 serotypes (1 and 2) of epizootic hemorrhagic disease (EHD) virus (EHDV), a closely related serogroup of orbiviruses. The results indicate that all BT viruses are genetically related to each other and although EHDV-1 and EHDV-2 originated from a common gene pool, the 2 serogroups, EHDV and BTV, are not genetically interactive.
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Sugiyama
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Rao
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Kusari
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Purdy
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Collisson
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D001820:Bluetongue virus / Q000145:classification / Q000235:genetics; D008970:Molecular Weight; D009843:Oligoribonucleotides / Q000032:analysis; D010446:Peptide Fragments / Q000032:analysis; D012330:RNA, Double-Stranded / Q000032:analysis; D012367:RNA, Viral / Q000032:analysis; D012087:Reoviridae / Q000145:classification / Q000235:genetics*; D012703:Serotyping; D013045:Species Specificity; D014481:United States; D014764:Viral Proteins / Q000032:analysis
D009843:Oligoribonucleotides; D010446:Peptide Fragments; D012330:RNA, Double-Stranded; D012367:RNA, Viral; D014764:Viral Proteins