title: Simultaneous aortic reconstruction and bilateral renal revascularization. Is this a safe and effective procedure?
abstract: Between 1982 and 1987, 32 patients with severe aortorenal atherosclerosis had simultaneous aortic and bilateral renal revascularization. All patients were hypertensive. Eighteen patients (56%) had renal insufficiency with a mean serum creatinine (SC) of 2.8 mg/dl. Nine patients had an aortic aneurysm; the remaining 23 patients had aortoiliac occlusive disease of varying severity. Aortic reconstruction was done with either a straight (six patients) or bifurcated (26 patients) Dacron graft. Renal revascularization was accomplished with either bypass (60 arteries) or transaortic endarterectomy (four arteries). One patient died of pulmonary embolism (operative mortality rate 3%). Beneficial blood pressure response was achieved in 28 of 31 survivors, (90%). Among the 18 patients with renal insufficiency, mean SC was 2.80 +/- 1.18 mg/dl preoperatively and 1.65 +/- 0.48 mg/dl postoperatively (p less than 0.001). Among eight patients with severe renal dysfunction before surgery (SC greater than 3 mg/dl), mean SC was 3.90 +/- 0.85 mg/dl before and 1.79 +/- 0.69 mg/dl after operation (p less than 0.001). In follow-up extending to 58 months (mean 27.6 months), five late deaths occurred; cumulative survival was 94% at 2 years and 60% at 4 years. There were no instances of worsening hypertension; one patient had deteriorating renal function. These results indicate that severe aortorenal atherosclerosis can be managed with simultaneous aortic reconstruction and bilateral renal revascularization at low operative risk. In addition, there can be high expectation of significant and persisting benefit in both hypertension and renal dysfunction after operation.
authors.affiliation: Mississippi Baptist Medical Center, Jackson.
authors.forename: C S
authors.initials: CS
authors.lastname: O'Mara
authors.forename: M D
authors.initials: MD
authors.lastname: Maples
authors.forename: T L
authors.initials: TL
authors.lastname: Kilgore
authors.forename: M H
authors.initials: MH
authors.lastname: McMullan
authors.forename: H B
authors.initials: HB
authors.lastname: Tyler
authors.forename: G H
authors.initials: GH
authors.lastname: Mundinger
authors.forename: R E
authors.initials: RE
authors.lastname: Kennedy
mesh_terms: D000368:Aged; D001012:Aorta, Abdominal / Q000601:surgery; D001018:Aortic Diseases / Q000401:mortality / Q000601:surgery*; D001161:Arteriosclerosis / Q000401:mortality / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D004691:Endarterectomy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011093:Polyethylene Terephthalates; D012077:Renal Artery / Q000601:surgery; D012078:Renal Artery Obstruction / Q000401:mortality / Q000601:surgery*; D012307:Risk Factors
chemical_list: D011093:Polyethylene Terephthalates