[Parathyroid crisis. Fatal course despite control of hypercalcemia with mithramycin].
A 73-year-old patient suddenly became confused and comatose due to excessive hypercalcemia. He developed acute respiratory distress syndrome (ARDS) and died even though the hypercalcemic state had been brought under control with mithramycin. Autopsy disclosed an adenoma of the parathyroid gland and calcifications in lung and kidney tissues as well as hyaline membranes. The case illustrates the poor prognosis of hyperparathyroid crisis whenever organ damage is present.
Fäh
L
L
Medizinische Abteilung, Kantonsspital Schaffhausen.
Gloor
H J
HJ
D000208:Acute Disease; D000236:Adenoma / Q000150:complications; D000368:Aged; D006801:Humans; D006934:Hypercalcemia / Q000188:drug therapy* / Q000209:etiology; D006962:Hyperparathyroidism, Secondary / Q000150:complications* / Q000209:etiology; D008297:Male; D010282:Parathyroid Neoplasms / Q000150:complications; D008926:Plicamycin / Q000627:therapeutic use*; D012128:Respiratory Distress Syndrome / Q000209:etiology
D008926:Plicamycin
Parathyreotoxische Krise. Letaler Verlauf trotz Kontrolle der Hypercalcämie mit Mithramycin.