Hypotension after quinidine plus verapamil. Possible additive competition at alpha-adrenergic receptors.
Maisel
A S
AS
Motulsky
H J
HJ
Insel
P A
PA
D000368:Aged; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000188:drug therapy; D001667:Binding, Competitive; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007022:Hypotension / Q000139:chemically induced*; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D011802:Quinidine / Q000008:administration & dosage / Q000009:adverse effects*; D011869:Radioligand Assay; D051381:Rats; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects*; D014700:Verapamil / Q000008:administration & dosage / Q000009:adverse effects*
D011942:Receptors, Adrenergic, alpha; D014700:Verapamil; D011802:Quinidine