Phosphorylation of the sarcolemma of dystrophic and normal hamster muscle following denervation.
The rapid phosphorylation at 0 degree C of sarcolemma preparations of hamster leg muscle was compared with (Na+,K+)-ATPase activity in sham-operated and 7-day denervated muscle. The phosphorylation appeared to be under the trophic influence of the sciatic nerve since the denervated preparations exhibited a markedly reduced phosphorylation. In similar studies using dystrophic hamsters the sarcolemma preparations from sham-operated and denervated leg muscle both exhibited the same degree of phosphorylation.
Walkiewicz
M J
MJ
Nicholls
D M
DM
D000818:Animals; D006224:Cricetinae; D008297:Male; D008647:Mesocricetus; D009121:Muscle Denervation; D009124:Muscle Proteins / Q000378:metabolism; D009137:Muscular Dystrophy, Animal / Q000201:enzymology*; D010042:Ouabain / Q000494:pharmacology; D010766:Phosphorylation; D012508:Sarcolemma / Q000201:enzymology*; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*
D009124:Muscle Proteins; D010042:Ouabain; D000254:Sodium-Potassium-Exchanging ATPase