Lisuride infusion pump in Parkinson's disease. A report of two cases.
Two patients, ages 66 and 72, with complications of chronic levodopa therapy (random fluctuations, end of dose deterioration and dyskinesias) who were treated with Lisuride by means of a portable subcutaneous infusion pump are reported. Results obtained show significant improvement in disability through a net increase in the number of hours spent "on". Dyskinesias remained unmodified. Limiting psychiatric side effects were observed in one of the patients. Practical and technical aspects of the management of this therapeutic method are discussed.
Gershanik
O S
OS
Department of Neurology, Hospital Francés, Buenos Aires, Argentina.
Scipioni
O
O
García
S
S
D000368:Aged; D004334:Drug Administration Schedule; D003875:Drug Eruptions; D004359:Drug Therapy, Combination; D004409:Dyskinesia, Drug-Induced; D004873:Ergolines / Q000008:administration & dosage*; D006801:Humans; D007980:Levodopa / Q000008:administration & dosage / Q000627:therapeutic use; D008090:Lisuride / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D001523:Mental Disorders / Q000139:chemically induced; D010300:Parkinson Disease / Q000188:drug therapy* / Q000503:physiopathology
D004873:Ergolines; D007980:Levodopa; D008090:Lisuride