title: Distribution of water, fat, and metals in normal liver and in liver metastases influencing attenuation on computed tomography.
abstract: The quantity of water, lipid and some metals was measured in autopsy specimens of 8 normal livers, 9 livers with fatty change, and in 12 livers with metastases of various origins. These parameters contribute to the CT number measured in the liver. Water played a major role in demonstration of liver metastases as a low-density area on CT. Other contributory factors include iron, magnesium and zinc. Lipid and calcium had no influence in this respect. Heavy accumulation of calcium in a metastatic lesion gives a high-density area on CT. However, even when a metastatic lesion was perceived on CT as a low-density area, the calcium content of the lesion was not always lower than that of the non-tumour region.
authors.affiliation: Department of Radiology, Sumitomo Hospital, Osaka, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Ueda
authors.forename: Y
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Y
authors.initials: Y
authors.lastname: Kenko
authors.forename: H
authors.initials: H
authors.lastname: Koike
authors.forename: T
authors.initials: T
authors.lastname: Kubo
authors.forename: Y
authors.initials: Y
authors.lastname: Takano
authors.forename: K
authors.initials: K
authors.lastname: Hara
mesh_terms: D001834:Body Water / Q000032:analysis; D005234:Fatty Liver / Q000000981:diagnostic imaging*; D006801:Humans; D008055:Lipids / Q000032:analysis; D008099:Liver / Q000032:analysis / Q000000981:diagnostic imaging*; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D008670:Metals / Q000032:analysis; D014057:Tomography, X-Ray Computed
chemical_list: D008055:Lipids; D008670:Metals