Allogeneic bone marrow transplantation in multiple myeloma: a report of four cases.
Allogeneic bone marrow transplantation offers a new and promising form for treatment of multiple myeloma incurable with chemotherapy. We present four cases of advanced multiple myeloma given bone marrow transplantation from HLA-identical and MLC-negative sibling donors. One patient had a recurrent plasmacytoma 8 months later and one died 12 days after the transplantation whereas the other two are in good clinical remission 15 and 19 months post-transplantation.
Nikoskelainen
J
J
Department of Medicine, Turku University Central Hospital, Finland.
Koskela
K
K
Kätkä
K
K
Pelliniemi
T T
TT
Kulmala
J
J
Salmi
T
T
Toivanen
A
A
D000328:Adult; D016026:Bone Marrow Transplantation; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D006086:Graft vs Host Disease / Q000209:etiology; D006680:HLA Antigens; D006801:Humans; D007959:Lymphocyte Culture Test, Mixed; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000276:immunology / Q000628:therapy*
D006680:HLA Antigens; D003520:Cyclophosphamide