title: [Ceftazidime in the treatment of purulent meningitis].
abstract: Third generation cephalosporins have modified the first-line treatment of bacterial meningitis in adults and children. Among these compounds, ceftazidime has a particularly wide antibacterial spectrum, and clinical results have confirmed its superiority, notably in the treatment of meningitis caused by Pseudomonas spp. It is an excellent first-line empirical treatment while awaiting bacteriological results, but in view of the severity of these diseases and of the dangerous pathogens that are often involved, it seems preferable to combine ceftazidime with an aminoglycoside. Route of administration (systemic or in situ) and duration of treatment must be tailored to each individual case.
authors.affiliation: Clinique des Maladies infectieuses B (Enfants), Centre Gui de Chauliae, Montpellier.
authors.forename: J
authors.initials: J
authors.lastname: Astruc
mesh_terms: D000328:Adult; D000367:Age Factors; D002442:Ceftazidime / Q000627:therapeutic use*; D002648:Child; D006801:Humans; D008581:Meningitis / Q000188:drug therapy*
chemical_list: D002442:Ceftazidime
vernacular_title: La ceftazidime dans le traitement des méningites purulents.