Iodide accumulation into thyroid Golgi vesicles.
Pig thyroid Golgi vesicles incubated in a suitable medium were able to concentrate iodide from the medium. This trapping required the integrity of the vesicles, was time- and temperature-dependent, and was inhibited by a competitive inhibitor of iodide active transport (perchlorate), suggesting a facilitated transport mechanism.
Bastiani
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Rognoni
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JB
D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D006056:Golgi Apparatus / Q000378:metabolism*; D066298:In Vitro Techniques; D007454:Iodides / Q000378:metabolism*; D008247:Lysosomes / Q000378:metabolism; D008928:Mitochondria / Q000378:metabolism; D010472:Perchlorates / Q000494:pharmacology; D017670:Sodium Compounds; D013552:Swine; D013696:Temperature; D013961:Thyroid Gland / Q000378:metabolism* / Q000648:ultrastructure; D013997:Time Factors
D007454:Iodides; D010472:Perchlorates; D017670:Sodium Compounds; C031068:sodium perchlorate