title: Acute posterior multifocal placoid pigment epitheliopathy associated with cerebral vasculitis.
abstract: Acute multifocal posterior placoid pigment epitheliopathy (APMPPE) is an unusual self-limited retinal disorder that has been associated with various systemic complications. To our knowledge, three prior cases associated with cerebral vasculitis have been described. This article describes a patient with APMPPE and angiographically documented cerebral vasculitis who was notable because of (a) the presence of two different cerebral ischemic events, occurring 1 month apart, and (b) the long latency (3 months) between the onset of ocular symptoms and the second cerebral ischemic event. Recognition of the association between APMPPE and cerebral vasculitis may permit early treatment of CNS involvement and prevention of morbidity.
authors.affiliation: Department of Ophthalmology, University of Wisconsin, School of Medicine, Madison.
authors.forename: J M
authors.initials: JM
authors.lastname: Weinstein
authors.forename: G H
authors.initials: GH
authors.lastname: Bresnick
authors.forename: C L
authors.initials: CL
authors.lastname: Bell
authors.forename: R A
authors.initials: RA
authors.lastname: Roschmann
authors.forename: B R
authors.initials: BR
authors.lastname: Brooks
authors.forename: C M
authors.initials: CM
authors.lastname: Strother
mesh_terms: D000328:Adult; D001921:Brain / Q000098:blood supply*; D006801:Humans; D008297:Male; D010857:Pigment Epithelium of Eye; D012164:Retinal Diseases / Q000150:complications* / Q000175:diagnosis; D014657:Vasculitis / Q000150:complications* / Q000175:diagnosis