title: Hepatitis B surface antigen in hepatocellular carcinoma.
abstract: Hepatitis B surface antigen (HBs-Ag) was detected histologically (by victoria blue-nuclear fast red staining) in the liver in 20-40% of liver cirrhosis and/or hepatocellular carcinoma (hepatoma) cases. In hepatoma cases, HBs-Ag was usually found in non-cancerous areas of the liver. However, some HBs-Ag positive cells were also found dispersed in cancerous areas; these were regarded as HBs-Ag-infected non-cancerous hepatic cells remaining undestroyed. There were a few cases where inconsistency was found between the results of the immunofluorescence technique using anti HBs-Ag serum and victoria blue staining in detecting HBs-Ag. This phenomenon was rare in non-cancerous areas, but was relatively frequent in cancerous areas.
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: W
authors.initials: W
authors.lastname: Mori
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000276:immunology*; D004396:Coloring Agents; D005455:Fluorescent Antibody Technique; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006801:Humans; D008103:Liver Cirrhosis / Q000276:immunology; D008113:Liver Neoplasms / Q000276:immunology*; D009930:Organic Chemicals
chemical_list: D004396:Coloring Agents; D006514:Hepatitis B Surface Antigens; D009930:Organic Chemicals; C041370:victoria blue