Multi-dimensional analyses of behavior in mice treated with naltrexone.
The effects of naltrexone on the behavior in mice were investigated by using a multi-dimensional behavioral analyser. Within 15 min following observation, naltrexone preferentially suppressed the linear locomotion at the 10 and 30 mg/kg doses. The results suggest that naltrexone selectively disrupts the linear locomotion without affecting other behaviors in mice.
Ukai
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Kameyama
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D000818:Animals; D001921:Brain / Q000187:drug effects; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009043:Motor Activity / Q000187:drug effects*; D009270:Naloxone / Q000031:analogs & derivatives*; D009271:Naltrexone / Q000494:pharmacology*; D011957:Receptors, Opioid / Q000187:drug effects
D011957:Receptors, Opioid; D009270:Naloxone; D009271:Naltrexone