title: Abnormalities of chromosomes 1 and 11 in Wilms' tumor.
abstract: Cytogenetic studies were performed successfully on 14 cases of Wilms' tumor. Six cases had detectable rearrangements of 11p, and 7 cases had structural abnormalities of chromosome #1. Two cases with advanced stage disease showed multiple translocations, resulting in hypodiploidy with a normal DNA complement.
authors.forename: E C
authors.initials: EC
authors.lastname: Douglass
authors.forename: J A
authors.initials: JA
authors.lastname: Wilimas
authors.forename: A A
authors.initials: AA
authors.lastname: Green
authors.forename: A T
authors.initials: AT
authors.lastname: Look
mesh_terms: D002648:Child; D002675:Child, Preschool; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002900:Chromosomes, Human, 1-3; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D007223:Infant; D007621:Karyotyping; D007680:Kidney Neoplasms / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic; D009396:Wilms Tumor / Q000235:genetics*