title: Surgical options for patients with deep-seated brain tumors: computer-assisted stereotactic biopsy.
abstract: The histologic nature of deep-seated intracranial lesions can be determined by using a computer-assisted stereotactic biopsy technique. The procedures are performed with use of local anesthesia. A data base consisting of stereotactic computed tomographic scans and stereotactic cerebral angiography is acquired. Target coordinates and trajectory approach angles are calculated by using a computer system in the operating room. Since July 1984, 36 patients with a variety of pathologic lesions in various intracranial sites have undergone this procedure at our institution. Of the 36 patients thought to have neoplastic lesions preoperatively, 6 were found to have nonneoplastic lesions, information that was of importance in the therapeutic management of these patients. Of the 30 patients with tumors, 24 had astrocytomas of various grades, 3 had metastatic lesions, and an additional 3 had lymphomas. Computer-assisted stereotactic biopsy with arteriographic control is an accurate and relatively safe method of determining the histologic nature of any suspicious intracranial lesion.
authors.forename: P J
authors.initials: PJ
authors.lastname: Kelly
authors.forename: F
authors.initials: F
authors.lastname: Earnest
authors.forename: B A
authors.initials: BA
authors.lastname: Kall
authors.forename: S J
authors.initials: SJ
authors.lastname: Goerss
authors.forename: B
authors.initials: B
authors.lastname: Scheithauer
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary; D000293:Adolescent; D000328:Adult; D000368:Aged; D001254:Astrocytoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D001706:Biopsy / Q000009:adverse effects / Q000379:methods*; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D002648:Child; D005260:Female; D005909:Glioblastoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D006801:Humans; D008223:Lymphoma / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013238:Stereotaxic Techniques / Q000009:adverse effects; D014057:Tomography, X-Ray Computed / Q000379:methods*