N alpha-dimethylcoprogens. Three novel trihydroxamate siderophores from pathogenic fungi.
Three novel siderophores have been isolated from a highly pathogenic strain of Alternaria longipes (ATCC 26293). The compounds are N alpha-dimethylated analogs of coprogen, neocoprogen I and isoneocoprogen I. Structures of the compounds have been determined by 1H- and 13C-NMR, fast-atom-bombardment (FAB) mass spectroscopy and partial hydrolysis. One of the new compounds, N alpha-dimethylcoprogen, is also produced, as the major siderophore, in another fungus, Fusarium dimerum.
Jalal
M A
MA
Department of Chemistry, University of Oklahoma, Norman 73019.
Love
S K
SK
van der Helm
D
D
D000528:Alternaria / Q000032:analysis* / Q000472:pathogenicity; D005670:Fusarium / Q000032:analysis* / Q000472:pathogenicity; D006877:Hydroxamic Acids / Q000302:isolation & purification*; D007502:Iron Chelating Agents / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D017262:Siderophores
D006877:Hydroxamic Acids; D007502:Iron Chelating Agents; D017262:Siderophores; C065890:N(alpha)-dimethylneocoprogen; C065891:N(alpha)-dimethylisoneocoprogen I; C065863:N(alpha)-dimethylcoprogen