Immunological profile of chest x-ray-negative, asymptomatic asbestos workers.
Several immunologic parameters, both humoral and cellular, were studied in the serum and peripheral blood lymphocytes derived from chest x-ray-negative, asymptomatic asbestos workers. All humoral and cellular parameters were intact, except the con-A-induced T cell suppressor activity and T cell division in autologous mixed lymphocyte reaction, which were significantly elevated in the asbestos plant workers. The significance of these increased T cell activities in asbestos exposed people is not clear, and further clinical and immunological follow-up is warranted.
Lahat
N
N
Laboratory of Immunology, Carmel Hospital, Haifa, Israel.
Sobel
E
E
Djerassi
L
L
Kaufman
G
G
Horenstein
L
L
Gruener
N
N
D000974:Antibodies, Antinuclear / Q000032:analysis; D001194:Asbestos; D004781:Environmental Exposure; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000032:analysis; D007694:Killer Cells, Natural / Q000276:immunology; D008213:Lymphocyte Activation; D007959:Lymphocyte Culture Test, Mixed; D012217:Rheumatoid Factor / Q000032:analysis; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
D000974:Antibodies, Antinuclear; D007136:Immunoglobulins; D001194:Asbestos; D012217:Rheumatoid Factor