title: [A mathematical model of the dynamics of granulocytopoiesis in mammals].
abstract: A mathematical model has been developed for the dynamics of granulocytopoiesis in mammals subjected to chronic irradiation. The model involves a chalones mechanism of haemopoiesis regulation and comprises 12 nonlinear differential equations. The simulation results agree with the experimental data concerning the dynamics of granulocytopoiesis in rats affected by radiation within a wide range of dose rates.
authors.forename: T B
authors.initials: TB
authors.lastname: Zukhbaia
authors.forename: O A
authors.initials: OA
authors.lastname: Smirnova
mesh_terms: D000818:Animals; D002588:Cesium Radioisotopes; D005260:Female; D005720:Gamma Rays; D006098:Granulocytes; D006131:Growth Inhibitors / Q000502:physiology; D006410:Hematopoiesis; D008433:Mathematics; D008954:Models, Biological; D011833:Radiation Injuries, Experimental / Q000503:physiopathology*; D051381:Rats; D013997:Time Factors
chemical_list: D002588:Cesium Radioisotopes; D006131:Growth Inhibitors
vernacular_title: Matematicheskaia model' dinamiki granulotsitopoéza u mlekopitaiushchikh.