On the preparation of dihematoporphyrin ether-free hematoporphyrin derivative.
A dihematoporphyrin ether-free hematoporphyrin derivative has been prepared by a base-catalysed dehydration of hematoporphyrin with sodium hydroxide. The identification was performed by HPLC and mass spectroscopy (FD-MS). The reaction of hematoporphyrin with 1 M sodium hydroxide for 24 h yields more than 90% of the monomeric porphyrins.
Häberlein
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Abteilung für Klinische Biochemie im Fachbereich Humanmedizin der Philipps Universität Marburg.
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Doss
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D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D002851:Chromatography, High Pressure Liquid; D017323:Dihematoporphyrin Ether; D017324:Hematoporphyrin Derivative; D006415:Hematoporphyrins / Q000138:chemical synthesis* / Q000302:isolation & purification; D007202:Indicators and Reagents; D013058:Mass Spectrometry; D013053:Spectrophotometry
D000970:Antineoplastic Agents; D006415:Hematoporphyrins; D007202:Indicators and Reagents; D017324:Hematoporphyrin Derivative; D017323:Dihematoporphyrin Ether