title: Magnetic resonance imaging, computed tomography, and radionuclide scintigraphy in detection of liver metastases.
abstract: A series of 100 patients with suspected hepatic metastases was studied with magnetic resonance (MR), unenhanced computed tomography (CT), and radionuclide (RN) scintigraphy. Each set of images was read by three clinicians using a five-point scale to allow receiver operating characteristic (ROC) analysis using truth data derived from clinical review. Performance was measured by the areas under the ROC curves (0.940 +/- .018 for MR, 0.951 O +/- .013 for CT and 0.943 +/- .013 for RN) which were statistically not significantly different. We conclude that at their present level of development these three diagnostic examinations have equivalent performance and that MR is not superior in the detection of hepatic metastases.
authors.affiliation: Department of Medical Biophysics, St. Michael's Hospital, Toronto, Ontario.
authors.forename: M J
authors.initials: MJ
authors.lastname: Bronskill
authors.forename: R M
authors.initials: RM
authors.lastname: Henkelman
authors.forename: P Y
authors.initials: PY
authors.lastname: Poon
authors.forename: G N
authors.initials: GN
authors.lastname: Ege
authors.forename: H J
authors.initials: HJ
authors.lastname: Dunlap
authors.forename: C S
authors.initials: CS
authors.lastname: Ho
authors.forename: M
authors.initials: M
authors.lastname: Goldfinger
authors.forename: B R
authors.initials: BR
authors.lastname: Taylor
authors.forename: R M
authors.initials: RM
authors.lastname: Stone
authors.forename: S B
authors.initials: SB
authors.lastname: Sutcliffe
mesh_terms: D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging*; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008297:Male; D012372:ROC Curve; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed