title: [Bronchoalveolar lavage in patients with sarcoidosis--methodologic aspects of the collection, immunologic characterization of lymphocytes and studies of immunoglobulin content].
abstract: The activity of alveolitis in 25 patients with pulmonary sarcoidosis was determined by analysis of T-Lymphocytes and their subpopulations collected by broncho-alveolar lavage. The characterization of the lymphocytes was performed with monoclonal antibodies (BL-series). An amount of T-lymphocytes higher than 28% of all cells and a proportion of T4/T8-lymphocytes of 8:1 and over are signs of the activity of the alveolitis and an indication for corticoid therapy.
authors.affiliation: Robert-Koch-Klinik, Bezirkskrankenhaus für Lungenkrankheiten Leipzig, DDR.
authors.forename: A
authors.initials: A
authors.lastname: Ballin
authors.forename: H
authors.initials: H
authors.lastname: Bigl
authors.forename: S
authors.initials: S
authors.lastname: Ferner
authors.forename: H
authors.initials: H
authors.lastname: Fiebig
authors.forename: P
authors.initials: P
authors.lastname: Leonhardt
authors.forename: R
authors.initials: R
authors.lastname: Neubert
authors.forename: M
authors.initials: M
authors.lastname: Cebulla
mesh_terms: D000911:Antibodies, Monoclonal; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology*; D006801:Humans; D007136:Immunoglobulins / Q000378:metabolism*; D007958:Leukocyte Count; D008171:Lung Diseases / Q000276:immunology*; D012507:Sarcoidosis / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal; D007136:Immunoglobulins
vernacular_title: Broncho-alveoläre Lavage bei Sarkoidosepatienten--Methodische Aspekte der Gewinnung, immunologische Charakterisierung von Lymphozyten und Untersuchungen zum Immunglobulingehalt.