title: Parthenogenetic activation decreases the polyphosphoinositide content of frog eggs.
abstract: Polyphosphoinositides were quantified in metaphase II-arrested eggs of the amphibian Xenopus laevis and 8-10 min later in eggs activated by pricking. The content of phosphatidylinositol 4,5-biphosphate (PIP2) was remarkably high in metaphase II-arrested eggs with respect to that of phosphatidylinositol 4-phosphate (PIP). It was found to drop dramatically at activation. In contrast PIP content did not change significantly.
authors.forename: C j
authors.initials: Cj
authors.lastname: Le Peuch
authors.forename: A
authors.initials: A
authors.lastname: Picard
authors.forename: M
authors.initials: M
authors.lastname: Dorée
mesh_terms: D000818:Animals; D005260:Female; D005306:Fertilization; D008677:Metaphase; D009865:Oocytes / Q000187:drug effects / Q000378:metabolism*; D010312:Parthenogenesis; D019269:Phosphatidylinositol 4,5-Diphosphate; D018129:Phosphatidylinositol Phosphates; D010716:Phosphatidylinositols / Q000378:metabolism*; D011374:Progesterone / Q000494:pharmacology; D010738:Type C Phospholipases / Q000378:metabolism; D014981:Xenopus
chemical_list: D019269:Phosphatidylinositol 4,5-Diphosphate; D018129:Phosphatidylinositol Phosphates; D010716:Phosphatidylinositols; C037178:phosphatidylinositol 4-phosphate; D011374:Progesterone; D010738:Type C Phospholipases