title: [Nondisjunction of the chromosomes in man. Hypotheses and facts].
abstract: The data on nondisjunction of chromosomes in man, and particularly on chromosome 21 in Down syndrome, are presented in this review. New experimental data obtained by the differential staining technique are considered. These data enable us to revise a number of hypotheses on the causes and mechanisms of chromosome nondisjunction.
authors.forename: O A
authors.initials: OA
authors.lastname: Podugol'nikova
mesh_terms: D002871:Chromosome Banding; D002877:Chromosomes, Human / Q000648:ultrastructure*; D002891:Chromosomes, Human, Pair 21 / Q000648:ultrastructure; D004314:Down Syndrome / Q000209:etiology / Q000235:genetics; D006570:Heterochromatin / Q000235:genetics / Q000648:ultrastructure; D006801:Humans; D008540:Meiosis; D008938:Mitosis; D009630:Nondisjunction, Genetic
chemical_list: D006570:Heterochromatin
vernacular_title: Neraskhozhdenie khromosom u cheloveka. Gipotezy i fakty.