title: High blood pressure is a major factor in progression of diabetic nephropathy.
abstract: Arterial hypertension is a frequent finding, even early in the course of diabetic nephropathy. Systemic and glomerular hypertension enhance the development of diabetic glomerulopathy and accelerate the rate of decline in glomerular filtration rate in diabetic nephropathy. Conversely, effective antihypertensive treatment reduces albuminuria and diminishes the rate of decline in glomerular filtration rate, thereby postponing end-stage renal failure in diabetic nephropathy.
authors.affiliation: Hvidöre Hospital, Klampenborg, Denmark.
authors.forename: H H
authors.initials: HH
authors.lastname: Parving
authors.forename: E
authors.initials: E
authors.lastname: Hommel
mesh_terms: D000419:Albuminuria; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001794:Blood Pressure; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology*; D003928:Diabetic Nephropathies / Q000503:physiopathology*; D005919:Glomerular Filtration Rate; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*
chemical_list: D000959:Antihypertensive Agents