title: Beta-endorphin-like immunoreactivity increases in cerebrospinal fluid of acute head-injured patients.
abstract: beta-endorphin-like immunoreactivity (beta-ELI) was measured in cerebrospinal fluid (CSF) of 36 acute head-injured patients and 12 patients without head injury as controls. The mean level of beta-ELI in CSF of controls, mild cerebral contusions, and severe cerebral contusion patients were 51.9 +/- 5.6 pg/ml, 110.5 +/- 14.5 pg/ml, and 173.8 +/- 20.1 pg/ml respectively, with significant difference between them. The results also showed that beta-ELI may reflect the prognosis of acute head-injured patients.
authors.affiliation: Department of Neurosurgery, Chang Zheng Hospital, Second Military Medical College, Shanghai, People's Republic of China.
authors.forename: J J
authors.initials: JJ
authors.lastname: Yao
authors.forename: Z
authors.initials: Z
authors.lastname: Cheng
authors.forename: C C
authors.initials: CC
authors.lastname: Ce
authors.forename: W C
authors.initials: WC
authors.lastname: Hai
authors.forename: Z Y
authors.initials: ZY
authors.lastname: Xiang
authors.forename: L B
authors.initials: LB
authors.lastname: Cheng
mesh_terms: D001930:Brain Injuries / Q000134:cerebrospinal fluid; D006259:Craniocerebral Trauma / Q000134:cerebrospinal fluid*; D005260:Female; D006801:Humans; D008297:Male; D012016:Reference Values; D001615:beta-Endorphin / Q000134:cerebrospinal fluid*
chemical_list: D001615:beta-Endorphin