title: Radioimmunoassay for detection of VP1 specific neutralizing antibodies of foot and mouth disease virus.
abstract: A solid-phase radioimmunoassay was developed for the detection of antibodies against a specific region of the VP1 protein of the A24 and 01 serotypes of foot and mouth disease virus. The antibody titers from the radioimmunoassay showed a positive correlation with neutralizing antibody titers determined by a mouse protection assay. The specificity of the assay resides in the peptide used as antigen. The assay is rapid, reproducible and does not require the use of whole virions.
authors.forename: E J
authors.initials: EJ
authors.lastname: Patzer
authors.forename: M L
authors.initials: ML
authors.lastname: Jackson
authors.forename: D M
authors.initials: DM
authors.lastname: Moore
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D005537:Aphthovirus / Q000276:immunology*; D006168:Guinea Pigs; D051379:Mice; D011863:Radioimmunoassay; D014764:Viral Proteins / Q000276:immunology*; D015678:Viral Structural Proteins
chemical_list: D000914:Antibodies, Viral; D014764:Viral Proteins; D015678:Viral Structural Proteins