title: Hormonal profile and androgen status during the menstrual cycle in women with acne.
abstract: The androgen excess in women with acne can play an important role in gynecological endocrinology. LH, FSH, PRL, Testosterone (T), Androstenedione (A), Deydroepiandrosterone sulphate (DHEA-S) and Progesterone (P) were investigated in 21 women with uncomplicated idiopathic acne during the menstrual cycle. LF/FSH ratio greater than 3 was found in 7 cases (36.8%). Total T values were high in 90.4% of the whole group of women with acne (mean +/- SD 618.6 +/- 253.6, normal range 92-352 pg/ml). An ovulatory pattern of P was found in 66.65% of women with acne. Hyperprolactinemia was found in 23.6% of cases. The common denominator for ovulatory dysfunction in these women seems to be elevated LH levels, rather than elevated T levels.
authors.affiliation: Obstetric and Gynecologic Clinic-University of Studies of Cagliari, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Medda
authors.forename: R
authors.initials: R
authors.lastname: Nieddu
authors.forename: R
authors.initials: R
authors.lastname: Fiore
authors.forename: C
authors.initials: C
authors.lastname: Marcello
authors.forename: U
authors.initials: U
authors.lastname: Lecca
mesh_terms: D000152:Acne Vulgaris / Q000097:blood*; D000728:Androgens / Q000097:blood*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008597:Menstrual Cycle; D011388:Prolactin / Q000097:blood
chemical_list: D000728:Androgens; D012739:Gonadal Steroid Hormones; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone