[Effect of methadone administration on MHV-3 virus-induced experimental hepatitis in the mouse].
Mice treated with 15 mg/Kg/day methadone and infected with MHV-3 virus after 7 days did not show increased susceptibility to MHV-3 virus infection, did not develop more serious forms of hepatitis and not mortality did not increase with respect to the controls. Drug administration was continued for the duration of the experiment.
Chirianni
A
A
Guadagnino
V
V
Cangiano
F
F
Isabella
L
L
Villari
R
R
D000818:Animals; D006524:Hepatitis, Viral, Animal / Q000150:complications* / Q000401:mortality; D008099:Liver / Q000382:microbiology; D008691:Methadone / Q000633:toxicity*; D051379:Mice; D006517:Murine hepatitis virus / Q000302:isolation & purification; D014779:Virus Replication
D008691:Methadone
Effetto della somministrazione di metadone sulla epatite sperimentale del topo da virus MHV-3.