Bilateral optic neuropathy associated with amiodarone therapy.
Amiodarone, an antiarrhythmic agent, has been associated with mild visual loss secondary to papillopathy and papilledema. We report a patient who developed bilateral optic neuropathy 4 weeks after initiation of amiodarone therapy. Nine months later, his vision was 20/50 in the right eye and 20/200 in the left. This report provides additional evidence that amiodarone may cause toxic optic neuropathy.
Nazarian
S M
SM
Neurology Service, John L. McClellan Memorial Veterans Hospital, Little Rock, Arkansas 72205.
Jay
W M
WM
D000638:Amiodarone / Q000009:adverse effects* / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy; D009896:Optic Atrophy / Q000139:chemically induced / Q000473:pathology / Q000503:physiopathology; D009901:Optic Nerve Diseases / Q000139:chemically induced* / Q000473:pathology / Q000503:physiopathology; D014792:Visual Acuity; D014794:Visual Fields
D000638:Amiodarone