[B virus, delta agent and human immunodeficiency virus infections in drug addicts].
Infections with the B, D, A, NANB viruses and with the human immunodeficiency virus (HIV) are very common among drug addicts, some of whom may harbour several of these pathogens. The serum of 90 per cent of drug addicts contains one of the HBV markers, and 20 per cent of them carry an anti-D antibody which is more often present in HBs Ag-positive subjects but may also be found in those who are positive for anti-HBs and anti HBc antibodies. The presence of an anti-delta antibody increases the risk of severe histological lesions (chronic active hepatitis, cirrhosis), as does chronic alcoholism associated with drug addiction. Fifty to sixty per cent of drug addicts are seropositive for HIV. At the AIDS stage, hepatic lesions are extremely frequent (90 per cent), but they have low activity and are seldom responsible for death.
Buffet
C
C
Service des Maladies du foie et de l'appareil digestif, Hôpital de Bicêtre, Le Kremlin Bicêtre.
Gagnepain
A
A
Hagege
H
H
Balian
P
P
Espinoza
P
P
D000163:Acquired Immunodeficiency Syndrome / Q000209:etiology*; D006679:HIV Seropositivity / Q000209:etiology; D006509:Hepatitis B / Q000209:etiology*; D003699:Hepatitis D / Q000209:etiology*; D006801:Humans; D012307:Risk Factors; D019966:Substance-Related Disorders / Q000150:complications*
Les infections à virus B et delta et à virus de l'immunodéficience humaine chez les toxicomanes.