title: Age-related changes of methionine-enkephalin and beta-endorphin/beta-lipotropin immunoreactivity in human CSF.
abstract: Methionine-enkephalin (ME-IR) and beta-endorphin (BE-IR) immunoreactive material CSF concentrations have been measured in subjects of different ages affected by lumbar or cervical disk hernia. The two peptides exhibited different age-related trends. ME-IR levels rose significantly with age while no changes were observed in the case of BE-IR.
authors.affiliation: Department of Neurotraumatology, University of Padua, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Alessio
authors.forename: S
authors.initials: S
authors.lastname: Govoni
authors.forename: G
authors.initials: G
authors.lastname: Salar
authors.forename: F
authors.initials: F
authors.lastname: Battaini
authors.forename: R
authors.initials: R
authors.lastname: Iavicoli
authors.forename: M
authors.initials: M
authors.lastname: Trabucchi
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging / Q000134:cerebrospinal fluid*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004744:Enkephalin, Methionine / Q000134:cerebrospinal fluid*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay / Q000379:methods; D001615:beta-Endorphin / Q000134:cerebrospinal fluid*; D008083:beta-Lipotropin / Q000134:cerebrospinal fluid*
chemical_list: D004744:Enkephalin, Methionine; D001615:beta-Endorphin; D008083:beta-Lipotropin