title: Expression of the murine interferon gamma receptor in Xenopus laevis oocytes.
abstract: This study describes the isolation of mRNA for the murine interferon gamma receptor and its expression in frog oocytes. The binding properties and apparent molecular weight of the murine interferon gamma receptor protein synthesized in frog oocytes is similar to that found on mouse cells. This is the first report of a functional receptor for a polypeptide ligand (interferon gamma) expressed in and directly assayed on frog oocytes.
authors.affiliation: Department of Molecular Genetics and Microbiology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, Piscataway 08854.
authors.forename: C S
authors.initials: CS
authors.lastname: Kumar
authors.forename: T M
authors.initials: TM
authors.lastname: Mariano
authors.forename: M
authors.initials: M
authors.lastname: Noe
authors.forename: A K
authors.initials: AK
authors.lastname: Deshpande
authors.forename: P M
authors.initials: PM
authors.lastname: Rose
authors.forename: S
authors.initials: S
authors.lastname: Pestka
mesh_terms: D000818:Animals; D002461:Cell Line, Transformed; D005260:Female; D006031:Glycosylation; D007371:Interferon-gamma / Q000378:metabolism; D008228:Lymphoma, Non-Hodgkin / Q000032:analysis; D051379:Mice; D008807:Mice, Inbred BALB C; D008845:Microinjections; D008970:Molecular Weight; D008979:Moloney murine leukemia virus; D009865:Oocytes / Q000378:metabolism*; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000235:genetics / Q000302:isolation & purification; D011971:Receptors, Immunologic / Q000235:genetics* / Q000378:metabolism; D017471:Receptors, Interferon; D014407:Tumor Cells, Cultured; D014982:Xenopus laevis
chemical_list: D012333:RNA, Messenger; D011971:Receptors, Immunologic; D017471:Receptors, Interferon; D007371:Interferon-gamma