title: [Pregnancy: a way of recovering from prolactin-secreting adenoma? 18 cases].
abstract: Fifteen patients with prolactin-secreting pituitary adenoma completed a total of 18 pregnancies. Changes in blood prolactin levels and computerized tomographic images of the pituitary gland were studied. No increase in size of the adenoma was observed, and in 2 cases the tumour was found to be necrotic in the post-partum period. In all patients the prolactinaemia significantly decreased immediately after delivery. Thus, by inducing partial necrosis of the adenoma pregnancy may result in post-partum reduction of blood prolactin levels.
authors.affiliation: Service d'Endocrinologie et Médecine de la reproduction, Hôpital Necker, Paris.
authors.forename: C
authors.initials: C
authors.lastname: Bricaire
authors.forename: V
authors.initials: V
authors.lastname: Kerlan
authors.forename: F
authors.initials: F
authors.lastname: Kuttenn
authors.forename: P
authors.initials: P
authors.lastname: Mauvais-Jarvis
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D009336:Necrosis; D010911:Pituitary Neoplasms / Q000097:blood* / Q000000981:diagnostic imaging / Q000473:pathology; D049590:Postpartum Period / Q000097:blood; D011247:Pregnancy / Q000097:blood*; D011388:Prolactin / Q000097:blood*; D015175:Prolactinoma / Q000097:blood* / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography
chemical_list: D011388:Prolactin
vernacular_title: La grossesse: une modalité de guérison des adénomes à prolactine? Dix-huit observations.