title: Signet-ring-cell (colloid) carcinoma of the urinary bladder. Cytologic, histologic and ultrastructural findings in one case.
abstract: A 65-year-old female presented with a one-and-a-half-year history of intermittent, painless, gross hematuria. She was found to have a large bladder neoplasm. A cytologic diagnosis of signet-ring-cell (colloid) carcinoma was made on a bladder washing and was confirmed histologically by a cystoscopic biopsy. Subsequently, a radical cystectomy was performed. The cytologic findings of this rare pure signet-ring-cell carcinoma of the bladder, not previously described, are presented along with the histologic and ultrastructural findings.
authors.forename: R M
authors.initials: RM
authors.lastname: DeMay
authors.forename: M A
authors.initials: MA
authors.lastname: Grathwohl
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000473:pathology* / Q000648:ultrastructure; D000368:Aged; D001706:Biopsy; D002466:Cell Nucleolus / Q000648:ultrastructure; D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D001743:Urinary Bladder / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D014617:Vacuoles / Q000648:ultrastructure