title: The gene encoding the Ia-associated invariant chain is located on chromosome 18 in the mouse.
abstract: The chromosomal assignment of the gene encoding the invariant (Ii) chain associated with the mouse immune response antigens (Ia) was determined by Southern blot analysis of DNA from a panel of mouse X Chinese hamster somatic cell hybrids cleaved with Hind III or Eco RI. Using a mouse li cDNA as a hybridization probe, we localized the gene coding for the invariant chain to mouse chromosome 18.
authors.forename: K
authors.initials: K
authors.lastname: Yamamoto
authors.forename: G
authors.initials: G
authors.lastname: Floyd-Smith
authors.forename: U
authors.initials: U
authors.lastname: Francke
authors.forename: N
authors.initials: N
authors.lastname: Koch
authors.forename: W
authors.initials: W
authors.lastname: Lauer
authors.forename: B
authors.initials: B
authors.lastname: Dobberstein
authors.forename: R
authors.initials: R
authors.lastname: Schäfer
authors.forename: G J
authors.initials: GJ
authors.lastname: Hämmerling
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D006224:Cricetinae; D003412:Cricetulus; D004262:DNA Restriction Enzymes; D004274:DNA, Recombinant; D005347:Fibroblasts; D005819:Genetic Markers; D000949:Histocompatibility Antigens Class II / Q000235:genetics*; D006822:Hybrid Cells; D008297:Male; D051379:Mice / Q000276:immunology*; D009693:Nucleic Acid Hybridization
chemical_list: D004274:DNA, Recombinant; D005819:Genetic Markers; D000949:Histocompatibility Antigens Class II; D004262:DNA Restriction Enzymes