[Benign intracranial hypertension and minocycline].
A 19 year-old woman complained of headache and nausea occurring while she was taking minocycline for acne. Examination showed bilateral papilloedema and a bilateral VIth nerve palsy. Symptoms and signs rapidly resolved after the drug was stopped. Benign intracranial hypertension due to tetracyclines is well known in infants. It is rare in adults. Its pathophysiology remains unknown. The role of vitamin A is inconsistent. Others biological factors or personal susceptibility could be involved.
Lubetzki
C
C
Clinique de Neurologie et de Neuropsychologie, Hôpital de la Salpêtrière, Paris, France.
Sanson
M
M
Cohen
D
D
Schaison-Cusin
M
M
Lhermitte
F
F
Lyon-Caen
O
O
D000152:Acne Vulgaris / Q000188:drug therapy; D000328:Adult; D005260:Female; D006801:Humans; D008911:Minocycline / Q000009:adverse effects* / Q000627:therapeutic use; D011559:Pseudotumor Cerebri / Q000139:chemically induced*; D013754:Tetracyclines / Q000009:adverse effects*
D013754:Tetracyclines; D008911:Minocycline
Hypertension intracrânienne bénigne et minocycline.