title: A malignant cystosarcoma phyllodes with positive estrogen receptor and its heterotransplantation into nude mice.
abstract: We detected cytosol estrogen receptors in a malignant cystosarcoma phyllodes and succeeded in serial transplantations into athymic nude mice. The tumors of this transplantable strain (MC-3-JCK) have the same histologic features as the original tumors, and retain significant amounts of cytosol estrogen receptors. This strain appears to provide a useful experimental model for the study of biologic and therapeutic aspects of human cystosarcoma phyllodes of the breast.
authors.forename: Y
authors.initials: Y
authors.lastname: Tokuda
authors.forename: M
authors.initials: M
authors.lastname: Kubota
authors.forename: Y
authors.initials: Y
authors.lastname: Ueyama
authors.forename: K
authors.initials: K
authors.lastname: Maruo
authors.forename: J
authors.initials: J
authors.lastname: Hata
authors.forename: N
authors.initials: N
authors.lastname: Tamaoki
authors.forename: T
authors.initials: T
authors.lastname: Tajima
authors.forename: T
authors.initials: T
authors.lastname: Mitomi
mesh_terms: D000328:Adult; D000818:Animals; D001943:Breast Neoplasms / Q000032:analysis* / Q000473:pathology; D003600:Cytosol / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008819:Mice, Nude; D009368:Neoplasm Transplantation; D003557:Phyllodes Tumor / Q000032:analysis* / Q000473:pathology; D011960:Receptors, Estrogen / Q000032:analysis*; D014183:Transplantation, Heterologous
chemical_list: D011960:Receptors, Estrogen