title: [Cardiac involvement in Behçet's disease. 12 cases].
abstract: Fifteen cardiac manifestations observed in 12 of a series of 196 patients with Behçet's disease are reported. In this retrospective study conducted in an internal medicine department, 5 cases of pericarditis and 4 cases of myocardial infarction were encountered. The other cardiac manifestations were observed only once. They included ventricular aneurysm, endomyocardial fibrosis of the right heart, aortic insufficiency, mitral valve insufficiency, mitral valve prolapse, and right heart failure consecutive to pulmonary arterial hypertension. There was no relationship between the severity of cardiac lesions and that of the extracardiac manifestations of the disease. Comparison of these data with those found in the literature showed that pericarditis is the most frequent pathology, but it usually regresses rapidly. Lesions of the coronary arteries, with or without myocardial infarction, consist of stenosis, occlusion or pseudoaneurysm requiring surgical treatment. Myocardial lesions (with the possibility of pseudoaneurysm) and endomyocardial right heart fibrosis are exceptional but fairly characteristic of Behçet's disease which they should suggest. Hughes-Stovin's syndrome may be complicated by pulmonary arterial hypertension, although death is generally caused by massive haemoptysis.
authors.affiliation: Service de Médecine interne, Groupe hospitalier Pitié-Salpêtrière, Paris.
authors.forename: O
authors.initials: O
authors.lastname: Bletry
authors.forename: A
authors.initials: A
authors.lastname: Mohattane
authors.forename: B
authors.initials: B
authors.lastname: Wechsler
authors.forename: P
authors.initials: P
authors.lastname: Beaufils
authors.forename: P
authors.initials: P
authors.lastname: Valère
authors.forename: J
authors.initials: J
authors.lastname: Petit
authors.forename: R
authors.initials: R
authors.lastname: Gourgon
authors.forename: Y
authors.initials: Y
authors.lastname: Grosgogeat
authors.forename: P
authors.initials: P
authors.lastname: Godeau
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000150:complications*; D005260:Female; D006331:Heart Diseases / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology; D009205:Myocarditis / Q000209:etiology; D012189:Retrospective Studies
vernacular_title: Atteinte cardiaque de la maladie de Behçet. Douze observations.