Cutaneous lymphosarcoma of helper/inducer T-cell origin in a calf.
A calf with a lymphoproliferative disease resembling human mycosis fungoides, had multiple, ulcerated skin nodules with enlarged regional lymph nodes. Tumor cells were 10-15 micron in diameter and had round to oval nuclei without indentations. Mitoses were regularly present. Pautrier's microabscesses were in the epidermis, and T-cell areas of regional lymph nodes were infiltrated by neoplastic cells. Demonstration of the T-helper/inducer origin of neoplastic lymphocytes suggested classification in analogy with human mycosis fungoides.
Zwahlen
R D
RD
Institute of Veterinary Pathology and Large Animal Clinic, Veterinary School, University of Berne, Switzerland.
Tontis
A
A
Schneider
A
A
D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology*; D005260:Female; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary*; D008854:Microscopy, Electron; D012878:Skin Neoplasms / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary*; D006377:T-Lymphocytes, Helper-Inducer