title: Serum thymidine kinase as a prognostic marker in Hodgkin's disease.
abstract: In 72 of 81 consecutively diagnosed patients with Hodgkin's disease pretreatment sera were available for analysis of serum thymidine kinase (S-TK) levels. In relation to clinical parameters, such as stage, histopathology and general symptoms, significant correlations were found with higher (S-TK) levels in advanced disease as well as in patients with B-symptoms. When the prognostic ability was examined, patients in stages IA and IIA could be divided according to S-TK levels into two different groups in relation to disease-free survival. This latter finding makes this serum test interesting as an additional tool in the clinical evaluation and in the therapeutic decision concerning patients with Hodgkin's disease.
authors.forename: B
authors.initials: B
authors.lastname: Eriksson
authors.forename: H
authors.initials: H
authors.lastname: Hagberg
authors.forename: B
authors.initials: B
authors.lastname: Glimelius
authors.forename: C
authors.initials: C
authors.lastname: Sundström
authors.forename: S
authors.initials: S
authors.lastname: Gronowitz
authors.forename: C
authors.initials: C
authors.lastname: Källander
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006689:Hodgkin Disease / Q000201:enzymology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013937:Thymidine Kinase / Q000097:blood*
chemical_list: D013937:Thymidine Kinase