title: Staging of renal cell carcinoma: cost-effectiveness of routine preoperative bone scans.
abstract: The use of bone scans in the evaluation of renal cell carcinoma has become routine in many centers. In a retrospective analysis of 42 patients undergoing radical nephrectomy for renal cell carcinoma, we analyzed the cost-effectiveness of routine preoperative bone scans. Although these scans accurately predict metastatic disease to bone, they are not cost-effective as a routine preoperative tool because they do not alter outcome. In selected patients with bone pain and no other positive staging studies, preoperative bone scans may be of value in the decision to perform extirpative surgery.
authors.forename: R J
authors.initials: RJ
authors.lastname: Campbell
authors.forename: S B
authors.initials: SB
authors.lastname: Broaddus
authors.forename: G W
authors.initials: GW
authors.lastname: Leadbetter
mesh_terms: D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D002292:Carcinoma, Renal Cell / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D003362:Cost-Benefit Analysis; D011756:Diphosphates; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D009367:Neoplasm Staging; D009392:Nephrectomy; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D013667:Technetium; D016698:Technetium Tc 99m Pyrophosphate; D013997:Time Factors
chemical_list: D011756:Diphosphates; D016698:Technetium Tc 99m Pyrophosphate; D013667:Technetium