title: Adenylate cyclase activity in zona-free mouse oocytes.
abstract: Zona-free mouse oocytes, prepared by either chemical or enzymatic treatment, possess adenylate cyclase activity, since forskolin elevated cAMP to similar levels in either these oocytes or in oocytes with intact zonae. In addition, it was shown that oocyte isolation conditions can affect 'basal' cAMP levels.
authors.forename: E A
authors.initials: EA
authors.lastname: Bornslaeger
authors.forename: R M
authors.initials: RM
authors.lastname: Schultz
mesh_terms: D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D005576:Colforsin; D000242:Cyclic AMP / Q000378:metabolism; D004224:Diterpenes / Q000494:pharmacology; D005260:Female; D007700:Kinetics; D051379:Mice; D008855:Microscopy, Electron, Scanning; D009865:Oocytes / Q000201:enzymology* / Q000648:ultrastructure; D010063:Ovum / Q000502:physiology*; D015044:Zona Pellucida / Q000502:physiology*
chemical_list: D004224:Diterpenes; D005576:Colforsin; D000242:Cyclic AMP; D000262:Adenylyl Cyclases