[Results of a 2-year examination of patients with essential hypertension and left ventricular hypertrophy].
A study of 52 middle-aged males with essential hypertension, unaccompanied by cardiovascular disorders, is reported. The patients were divided into 2 groups with respect to the type of treatment they received: 30 patients on beta-adrenoblockers and 22 patients on methyldopa. The patients were treated continuously for 2 years under one-dimensional echocardiographic control. The greatest drop in arterial blood pressure and ventricular septum thickness was seen within the first 6 months of treatment, while posterior-wall hypertrophy disappeared altogether. Although there was no further drop in blood pressure after 6 months, the thickness of the ventricular septum remained reduced for at least 2 years. Regression of left-ventricular hypertrophy was not accompanied with any deterioration of left-ventricular performance, nor was it related to additional use of vasodilators.
Cifková
R
R
Niederle
P
P
Fridl
P
P
Skalická
G
G
Skibová
E
E
D000328:Adult; D006332:Cardiomegaly / Q000188:drug therapy* / Q000503:physiopathology; D002908:Chronic Disease; D004359:Drug Therapy, Combination; D004452:Echocardiography; D006321:Heart / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008137:Longitudinal Studies; D008297:Male; D009206:Myocardium / Q000473:pathology; D012074:Remission Induction
Rezul'taty dvukhgodichnogo obsledovaniia bol'nykh éssentsial'noĭ gipertonieĭ s gipertrofieĭ levogo zheludochka.