A mixed germ cell-sex cord-stromal tumor of the ovary with retiform tubular structure: a case report.
An unusual mixed tumor of the ovary in a 7-month-old girl with a normal 46,XX karyotype, is presented. The tumor was composed mainly of small epithelial cells of sex cord type, but also contained multiple foci in which the presence of large cells resembling germ cells warranted the diagnosis of mixed germ cell-sex cord-stromal tumor. An additional histologic feature was the presence in the fibrous stroma of the tumor of tubules of probable sex cord derivation arranged in a retiform pattern. These histologic features suggested that the tumor was a variant of the mixed germ cell-sex cord-stromal tumor of the ovary.
Tokuoka
S
S
Aoki
Y
Y
Hayashi
Y
Y
Yokoyama
T
T
Ishii
T
T
D005260:Female; D006801:Humans; D007223:Infant; D008854:Microscopy, Electron; D009373:Neoplasms, Germ Cell and Embryonal / Q000473:pathology* / Q000648:ultrastructure; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000648:ultrastructure