[Calcium metabolism in arterial hypertension. I. Myocardial hypertrophy and hormone-dependent increase in Ca2+ levels in the thrombocytes of patients with arterial hypertension].
Clonidine-treated patients with essential hypertension demonstrated reliable positive correlations between echocardiographically determined signs of myocardial hypertrophy (thickness of left ventricular posterior wall and interventricular septum, left ventricular myocardial mass) and hormone-dependent increase in thrombocyte calcium concentration induced by ADP and TAF. Antihypertensive therapy was more effective in patients with relatively weak cellular effect of Ca-increasing hormone response having no signs of myocardial hypertrophy.
Tkhostov
E B
EB
Atakhanov
Sh E
ShE
Men'shikov
M Iu
MIu
Iurenev
A P
AP
Mazaev
A V
AV
D000244:Adenosine Diphosphate / Q000502:physiology; D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000378:metabolism*; D002118:Calcium / Q000097:blood*; D006332:Cardiomegaly / Q000209:etiology*; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D006973:Hypertension / Q000097:blood / Q000150:complications*; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D008955:Models, Cardiovascular; D010972:Platelet Activating Factor / Q000502:physiology
D010972:Platelet Activating Factor; D000244:Adenosine Diphosphate; D002118:Calcium
Obmen kal'tsiia pri arterial'noĭ gipertonii. Soobshchenie I. Gipertrofiia miokarda i gormonzavisimoe uvelichenie kontsentratsii Ca2+ v trombotsitakh bol'nykh arterial'noĭ gipertonieĭ.