Activation of the carcinogen, 5-hydroxymethylchrysene, to the mutagenic sulphate ester by mouse skin sulphotransferase.
Okuda
H
H
Department of Hygienic Chemistry, Tokyo College of Pharmacy, Japan.
Nojima
H
H
Watanabe
N
N
Miwa
K
K
Watabe
T
T
D000818:Animals; D001711:Biotransformation; D002273:Carcinogens / Q000378:metabolism*; D002851:Chromatography, High Pressure Liquid; D002911:Chrysenes / Q000378:metabolism*; D003687:Dehydroepiandrosterone / Q000378:metabolism; D005260:Female; D008297:Male; D051379:Mice; D009596:Nitrophenols / Q000378:metabolism; D010616:Phenanthrenes / Q000378:metabolism*; D010724:Phosphoadenosine Phosphosulfate / Q000378:metabolism; D012867:Skin / Q000201:enzymology*; D013431:Sulfates / Q000378:metabolism; D013466:Sulfurtransferases / Q000378:metabolism*
D002273:Carcinogens; D002911:Chrysenes; D009596:Nitrophenols; D010616:Phenanthrenes; D013431:Sulfates; D003687:Dehydroepiandrosterone; D010724:Phosphoadenosine Phosphosulfate; C032670:5-hydroxymethylchrysene; D013466:Sulfurtransferases; C024836:4-nitrophenol