title: [Transposition immunity in bacteriophage Mu. The effect of a mutation at the kil gene on the establishment of immunity].
abstract: Bacteriophage Mu is characterized by a phenomenon similar to the transposition immunity of TnA: the frequency of transposition of Mu or mini-Mu into plasmids containing certain phage sequences is reduced by two orders of magnitude. In order to lend transposition immunity to Mu, the recipient replicon must contain a sequence of phage DNA including a 5.1 kb early region from the c-end of Mu. The product of the kil (or cim) gene takes part in establishing the immunity. The transposition immunity of Mu is connected with the disturbance of cointegrate formation.
authors.forename: M A
authors.initials: MA
authors.lastname: Mogutov
authors.forename: G A
authors.initials: GA
authors.lastname: Velikodvorskaia
authors.forename: N S
authors.initials: NS
authors.lastname: Kobets
authors.forename: E S
authors.initials: ES
authors.lastname: Piruzian
mesh_terms: D002876:Chromosomes, Bacterial; D003090:Coliphages / Q000235:genetics* / Q000276:immunology; D004251:DNA Transposable Elements; D004279:DNA, Viral / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics; D005814:Genes, Viral; D007109:Immunity; D009154:Mutation; D010957:Plasmids; D012093:Replicon
chemical_list: D004251:DNA Transposable Elements; D004279:DNA, Viral
vernacular_title: Immunnost' transpozitsii bakteriofaga Mu. Vliianie mutatsii po genu kil na ustanovlenie immunnosti.