Construction of a viable simian virus 40 variant that carries a poly[d(GT) . d(CA)] insertion.
A 90-base-pair tract of a simple sequence composed of alternating guanosine and thymidine nucleotide residues (poly[d(GT) . d(CA)]) was inserted into the simian virus 40 genome at nucleotide 2666 (0.17 map units). The poly[d(GT) . d(CA)] insertion was stably maintained in the viral genome, but the variant virus grew more slowly than simian virus 40.
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D000818:Animals; D002460:Cell Line; D005814:Genes, Viral; D014644:Genetic Variation; D011089:Polydeoxyribonucleotides / Q000235:genetics*; D013539:Simian virus 40 / Q000235:genetics* / Q000254:growth & development
D011089:Polydeoxyribonucleotides; C044165:poly(d(G-T).d(C-A))