title: An indwelling subcutaneous FEP cannula for intermittent insulin injection: patient experience and effect on diabetic control.
abstract: The acceptability and efficacy of injecting insulin through a subcutaneous FEP cannula (to reduce the frequency of needle pricks) compared with conventional multiple injection therapy was examined in a cross-over study. Thirty-two insulin-dependent diabetic patients injected through the cannula for 10 weeks using a pen injector, followed by 10 weeks using the injector alone, or vice versa. Rapid-acting insulin was given before meals and intermediate-acting insulin at bedtime. Blood glucose control was not affected by cannula use (glycosylated haemoglobin: cannula, 8.6 +/- 0.3%; no cannula, 8.6 +/- 0.3%). Twenty-two of the 30 patients completing the study preferred to use the cannula and 21 requested to continue using it. There were no complications associated with its use.
authors.affiliation: Department of Endocrinology, Charing Cross Hospital, London, UK.
authors.forename: G
authors.initials: G
authors.lastname: Rayman
authors.forename: P H
authors.initials: PH
authors.lastname: Wise
mesh_terms: D000328:Adult; D002408:Catheters, Indwelling; D003258:Consumer Behavior; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000188:drug therapy*; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007279:Injections, Subcutaneous / Q000295:instrumentation* / Q000379:methods; D007328:Insulin / Q000008:administration & dosage* / Q000627:therapeutic use; D011795:Surveys and Questionnaires
chemical_list: D006442:Glycated Hemoglobin; D007328:Insulin