The reversion of temperature-sensitive mutants of encephalomyocarditis virus upon serial passage in three continuous cell lines.
Several temperature-sensitive mutants of encephalomyocarditis virus were serially passed numerous times in HeLa, L929 and BHK-21 cells. The reversion of most of the mutants occurred most rapidly in BHK-21 cells and least rapidly in HeLa cells.
Radloff
R J
RJ
D000818:Animals; D002460:Cell Line; D006224:Cricetinae; D004686:Encephalomyocarditis virus / Q000235:genetics*; D006367:HeLa Cells / Q000382:microbiology; D006801:Humans; D007668:Kidney; D008647:Mesocricetus; D009154:Mutation; D013045:Species Specificity; D013696:Temperature; D014776:Virus Cultivation