title: Isolation from cats of an endogenous type C virus with a novel envelope glycoprotein.
abstract: A search for variant endogenous cat viruses led to a novel isolate. Although the major envelope glycoprotein of this virus was similar in size to that of an RD-114-like virus that was coisolated, it was unrelated to RD-114 or feline leukemia virus by immunological and biological criteria. This degree of dissimilarity suggests a different evolutionary progenitor from that for the RD-114 and feline leukemia virus viral envelopes. The novel virus did, however, code for gag gene polypeptides which are closely related to RD-114 virus. Neither the novel isolate nor the RD-114-like coisolate induced foci in S+L- cat cells which restrict focus induction by RD-114 virus. This suggests that the two viruses share a common genomic target of restriction which resides outside of the env region.
authors.forename: D K
authors.initials: DK
authors.lastname: Haapala
authors.forename: W G
authors.initials: WG
authors.lastname: Robey
authors.forename: S D
authors.initials: SD
authors.lastname: Oroszlan
authors.forename: W P
authors.initials: WP
authors.lastname: Tsai
mesh_terms: D000818:Animals; D002415:Cats / Q000382:microbiology*; D005814:Genes, Viral; D006023:Glycoproteins / Q000032:analysis*; D012190:Retroviridae / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D014759:Viral Envelope Proteins / Q000032:analysis*; D014762:Viral Interference
chemical_list: D006023:Glycoproteins; D014759:Viral Envelope Proteins