Modulation of autologous mixed lymphocyte reaction by pharmacological agents affecting adrenergic receptor.
The effect of epinephrine and propranolol administration in vivo on autologous mixed lymphocyte reaction (AMLR) was investigated. AMLR inhibition by epinephrine and potentiation of AMLR after propranolol injection was found. Presumable mechanisms of these changes in the light of beta-receptor agonist and antagonist are discussed.
Zeman
K
K
Department of Pathophysiology, Institute of Basic Medical Sciences, WAM, Lodź.
Malec
P
P
D000328:Adult; D004837:Epinephrine / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D007959:Lymphocyte Culture Test, Mixed; D008214:Lymphocytes / Q000187:drug effects / Q000502:physiology*; D011433:Propranolol / Q000494:pharmacology; D011941:Receptors, Adrenergic / Q000187:drug effects*
D011941:Receptors, Adrenergic; D011433:Propranolol; D004837:Epinephrine