title: Comparison of enzyme activities on glycogen metabolism in rabbit slow and fast muscles.
abstract: Activities of glycogen synthase (total) and branching enzyme in slow (soleus) muscle are higher than those in fast (vastus lateralis) muscle, while those of phosphorylase kinase (total), phosphorylase (total) and debranching enzyme are reversed. The active form ratio of glycogen synthase is higher in fast muscle, while those of phosphorylase kinase and phosphorylase are higher in slow muscle. Activities of cAMP-dependent protein kinase and protein phosphatase in slow muscle are higher than those in fast muscle. These results suggest that glycogen metabolizing enzymes in slow muscle, distinct from those in fast muscle, are regulated more strongly by cAMP-dependent protein kinase rather than by protein phosphatase.
authors.forename: A
authors.initials: A
authors.lastname: Tsutou
authors.forename: S
authors.initials: S
authors.lastname: Nakamura
authors.forename: A
authors.initials: A
authors.lastname: Negami
authors.forename: T
authors.initials: T
authors.lastname: Nakaza
authors.forename: T
authors.initials: T
authors.lastname: Kobayashi
authors.forename: K
authors.initials: K
authors.lastname: Mizuta
authors.forename: E
authors.initials: E
authors.lastname: Hashimoto
authors.forename: H
authors.initials: H
authors.lastname: Yamamura
mesh_terms: D000818:Animals; D005964:Glucosyltransferases / Q000378:metabolism*; D006003:Glycogen / Q000378:metabolism*; D006004:Glycogen Debranching Enzyme System / Q000378:metabolism*; D006006:Glycogen Synthase / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D009132:Muscles / Q000201:enzymology*; D009928:Organ Specificity; D010749:Phosphoprotein Phosphatases / Q000378:metabolism; D010761:Phosphorus Radioisotopes; D010764:Phosphorylase Kinase / Q000378:metabolism*; D006005:Phosphorylases / Q000378:metabolism*; D011494:Protein Kinases / Q000378:metabolism; D011817:Rabbits
chemical_list: D006004:Glycogen Debranching Enzyme System; D010761:Phosphorus Radioisotopes; D006003:Glycogen; D005964:Glucosyltransferases; D006005:Phosphorylases; D006006:Glycogen Synthase; D011494:Protein Kinases; D010764:Phosphorylase Kinase; D010749:Phosphoprotein Phosphatases