title: Identification of five new variable restriction sites in HSV-1 DNA.
abstract: Restriction endonuclease analysis of herpes simplex virus type 1 (HSV-1) DNA has shown that individual strains differ from one another. The differences can be recognized by the presence or absence of cleavage sites due to base changes, small insertions and occasional deletions. In a study in which 13 HSV-1 isolates from South Africa were analysed, a total of 5 new variable restriction sites were identified using the restriction endonucleases Hind III, Eco RI and Bgl II.
authors.forename: B A
authors.initials: BA
authors.lastname: Wylie
authors.forename: J A
authors.initials: JA
authors.lastname: Thomson
authors.forename: B D
authors.initials: BD
authors.lastname: Schoub
mesh_terms: D001426:Bacterial Proteins; D004262:DNA Restriction Enzymes; D004279:DNA, Viral / Q000032:analysis*; D015246:Deoxyribonuclease EcoRI; D015247:Deoxyribonuclease HindIII; D015252:Deoxyribonucleases, Type II Site-Specific; D005814:Genes, Viral; D066298:In Vitro Techniques; D018139:Simplexvirus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D013019:South Africa
chemical_list: D001426:Bacterial Proteins; D004279:DNA, Viral; D004262:DNA Restriction Enzymes; D015246:Deoxyribonuclease EcoRI; D015247:Deoxyribonuclease HindIII; C024404:BglII endonuclease; D015252:Deoxyribonucleases, Type II Site-Specific