title: Peroxidase-catalysed iodotyrosine formation in dispersed cells of mouse extrathyroidal tissues.
abstract: A method has been developed for the isolation of cells, high in iodine uptake and peroxidase activity, from the stomach and submaxillary gland of mice. The isolated cells could produce protein-bound monoiodotyrosine, di-iodotyrosine and an unknown iodocompound. The reactions were catalysed by peroxidase and were sensitive to antithyroid drugs and haemoprotein inhibitors but were insensitive to TSH. In-vitro iodination of stomach or submaxillary soluble proteins with the respective peroxidase yielded similar iodocompounds while thyroxine was produced when thyroglobulin was used instead.
authors.forename: R K
authors.initials: RK
authors.lastname: Banerjee
authors.forename: A K
authors.initials: AK
authors.lastname: Bose
authors.forename: T K
authors.initials: TK
authors.lastname: Chakraborty
authors.forename: S K
authors.initials: SK
authors.lastname: De
authors.forename: A G
authors.initials: AG
authors.lastname: Datta
mesh_terms: D000818:Animals; D002469:Cell Separation; D005753:Gastric Mucosa / Q000378:metabolism*; D007454:Iodides / Q000378:metabolism; D007527:Isoenzymes / Q000378:metabolism*; D007700:Kinetics; D051379:Mice; D008815:Mice, Inbred Strains; D007470:Monoiodotyrosine / Q000096:biosynthesis*; D009195:Peroxidase; D010544:Peroxidases / Q000378:metabolism*; D013270:Stomach / Q000166:cytology; D013363:Submandibular Gland / Q000166:cytology / Q000378:metabolism*
chemical_list: D007454:Iodides; D007527:Isoenzymes; D010544:Peroxidases; D009195:Peroxidase; D007470:Monoiodotyrosine