title: Construction of linkage maps with DNA markers for human chromosomes.
abstract: DNA markers and sampling of three-generation families can be used to construct complete linkage maps of human chromosomes. This is important in mapping disease loci and in determining the genetic or environmental component of a disease.
authors.forename: R
authors.initials: R
authors.lastname: White
authors.forename: M
authors.initials: M
authors.lastname: Leppert
authors.forename: D T
authors.initials: DT
authors.lastname: Bishop
authors.forename: D
authors.initials: D
authors.lastname: Barker
authors.forename: J
authors.initials: J
authors.lastname: Berkowitz
authors.forename: C
authors.initials: C
authors.lastname: Brown
authors.forename: P
authors.initials: P
authors.lastname: Callahan
authors.forename: T
authors.initials: T
authors.lastname: Holm
authors.forename: L
authors.initials: L
authors.lastname: Jerominski
mesh_terms: D002874:Chromosome Mapping; D002877:Chromosomes, Human; D004262:DNA Restriction Enzymes; D030342:Genetic Diseases, Inborn / Q000235:genetics*; D008040:Genetic Linkage; D006579:Heterozygote; D006801:Humans; D010375:Pedigree; D011995:Recombination, Genetic
chemical_list: D004262:DNA Restriction Enzymes