title: Interfering with taste aversion learning in rats: the role of associative interference.
abstract: Six experiments with rats investigated the conditions under which one flavor interferes with aversion conditioning to a second, familiar flavor. Conditioning to the familiar flavor was weakest when the interference flavor was contiguous to lithium-induced toxicosis, novel, more intense, and strongly associated with toxicosis. In addition, conditioning to the familiar flavor was weakened even if multiple conditioning trials were used. The repeated finding of an inverse relationship between strength of aversion to the target and interference flavors is interpreted as support for an associative competition hypothesis of the interference effect. The possible relevance of the interference effect to the attenuation of taste aversions in cancer patients is discussed.
authors.forename: D S
authors.initials: DS
authors.lastname: Cannon
authors.forename: M R
authors.initials: MR
authors.lastname: Best
authors.forename: J D
authors.initials: JD
authors.lastname: Batson
authors.forename: E R
authors.initials: ER
authors.lastname: Brown
authors.forename: J A
authors.initials: JA
authors.lastname: Rubenstein
authors.forename: L E
authors.initials: LE
authors.lastname: Carrell
mesh_terms: D000818:Animals; D001245:Association Learning / Q000187:drug effects; D001362:Avoidance Learning / Q000187:drug effects; D002712:Chlorides / Q000633:toxicity; D003214:Conditioning, Classical / Q000187:drug effects; D004193:Discrimination Learning / Q000187:drug effects; D004326:Drinking / Q000187:drug effects; D007858:Learning / Q000187:drug effects; D008094:Lithium / Q000633:toxicity; D018021:Lithium Chloride; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013649:Taste / Q000187:drug effects
chemical_list: D002712:Chlorides; D008094:Lithium; D018021:Lithium Chloride