title: Correlation between facial involuntary movements and abnormalities of blink and corneal reflexes in Huntington's chorea.
abstract: Blink and corneal reflexes were studied in 11 patients with Huntington's chorea and the results compared with the severity of the disease. The latency of the R2 component of the blink reflex was delayed and the duration of R2 and of the corneal reflex (CR) prolonged. A greater habituation of the R2 component was found in the patients with involuntary movements in the face, and in some patients a long-lasting depression of R2 was present. A correlation was found between: (a) severity of involuntary face movements and R2 and CR latency and (b) severity of involuntary movements in the neck and latency of R2.
authors.affiliation: Dipartimento di Scienze Neurologiche, Università di Roma, La Sapienza, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Agostino
authors.forename: A
authors.initials: A
authors.lastname: Berardelli
authors.forename: G
authors.initials: G
authors.lastname: Cruccu
authors.forename: G
authors.initials: G
authors.lastname: Pauletti
authors.forename: F
authors.initials: F
authors.lastname: Stocchi
authors.forename: M
authors.initials: M
authors.lastname: Manfredi
mesh_terms: D000293:Adolescent; D000328:Adult; D001767:Blinking; D004298:Dopamine / Q000502:physiology; D004576:Electromyography; D005152:Facial Muscles / Q000503:physiopathology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006185:Habituation, Psychophysiologic / Q000502:physiology; D006801:Humans; D006816:Huntington Disease / Q000235:genetics / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011930:Reaction Time / Q000502:physiology; D012025:Reflex, Pupillary; D014276:Trigeminal Nerve / Q000503:physiopathology
chemical_list: D004298:Dopamine