title: [5-year survival rate in acute transmural heart infarct following thrombolysis and immediate coronary angioplasty].
abstract: Two-hundred-eighty-six patients with acute transmural myocardial infarction underwent thrombolytic treatment (Streptokinase) between 1980 and 1986. In the earlier years patients were treated by thrombolysis only (n = 158) and in more recent years by thrombolysis followed by immediate percutaneous transluminal coronary angioplasty (n = 128). Age, sex, incidence of previous infarction and incidence of multivessel disease were comparable between groups. Patency of the infarct vessel (TIMI 3) was higher after thrombolysis combined with angioplasty than after thrombolysis alone (87% vs. 70%, p less than 0.001), and the residual stenosis of the infarct vessel was lower (46% vs. 84%, p less than 0.05). Hospital mortality (thrombolysis combined with angioplasty vs. thrombolysis alone) was 6% vs. 13%; one-year mortality was 8% vs. 21%, and five-year mortality was 18% vs. 31% (p less than 0.02). We conclude that treatment of patients with acute transmural myocardial infarction by thrombolysis combined with angioplasty is followed by a better long-term prognosis than treatment by thrombolysis only.
authors.affiliation: Rotes-Kreuz-Krankenhaus, Abt. Kardiologie, Frankfurt am Main.
authors.forename: F
authors.initials: F
authors.lastname: Schwarz
authors.forename: B
authors.initials: B
authors.lastname: Weyland
authors.forename: H
authors.initials: H
authors.lastname: Tillmanns
authors.forename: G
authors.initials: G
authors.lastname: Schuler
authors.forename: J
authors.initials: J
authors.lastname: Manthey
authors.forename: R
authors.initials: R
authors.lastname: Dietz
authors.forename: W
authors.initials: W
authors.lastname: Kübler
authors.forename: M
authors.initials: M
authors.lastname: Olschewski
mesh_terms: D000800:Angioplasty, Balloon; D003131:Combined Modality Therapy; D017023:Coronary Angiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality / Q000628:therapy*; D013300:Streptokinase / Q000008:administration & dosage* / Q000009:adverse effects
chemical_list: D013300:Streptokinase
vernacular_title: Fünf-Jahres-Uberlebensrate des akuten transmuralen Herzinfarktes nach Thrombolyse und sofortiger Koronarangioplastie.