title: Additional improvement of stenosis geometry in human coronary arteries by stenting after balloon dilatation.
abstract: The purpose of this study was to assess the early changes in stenosis geometry after insertion of intravascular stents in human coronary arteries. Morphologic changes were evaluated by quantitative coronary angiography (using automated edge detection) and by calculation of the theoretical pressure decrease across the dilated and stented stenosis from the Poiseuille and turbulent resistances assuming a coronary blood flow of either 1 or 3 ml/s. Twenty-six patients were studied before and after angioplasty, as well as immediately after stent implantation. The stented coronary artery was the left anterior descending artery in 19 cases, the circumflex artery in 2 cases, the right coronary artery in 2 cases and a coronary artery bypass vein graft in 3 cases. After stent implantation, an additional increase in minimal luminal cross-sectional area of the dilated vessel was observed, suggesting that the self-expanding stainless steel endoprosthesis used in this study has a dilating function in addition to its stenting role.
authors.affiliation: Catheterization Laboratory, Erasmus University, Rotterdam, The Netherlands.
authors.forename: P W
authors.initials: PW
authors.lastname: Serruys
authors.forename: Y
authors.initials: Y
authors.lastname: Juilliere
authors.forename: M E
authors.initials: ME
authors.lastname: Bertrand
authors.forename: J
authors.initials: J
authors.lastname: Puel
authors.forename: A F
authors.initials: AF
authors.lastname: Rickards
authors.forename: U
authors.initials: U
authors.lastname: Sigwart
mesh_terms: D000792:Angiography; D000800:Angioplasty, Balloon; D003251:Constriction, Pathologic / Q000517:prevention & control; D017023:Coronary Angiography; D003327:Coronary Disease / Q000628:therapy*; D003331:Coronary Vessels; D005260:Female; D006801:Humans; D008297:Male; D019736:Prostheses and Implants; D012008:Recurrence; D013193:Stainless Steel
chemical_list: D013193:Stainless Steel