Efficacy of delayed percutaneous transluminal coronary angioplasty after intravenous use of streptokinase in myocardial infarction.
Between June 1984 and December 1986, 35 patients with acute myocardial infarction received streptokinase intravenously within 3 hours after the beginning of chest pain and underwent percutaneous transluminal coronary angioplasty (PTCA) either immediately (in 2 cases) or 1 to 19 (mean 4.4) days later (in 33). The rate of successful PTCA was 89%. Reocclusion occurred in one patient. The mean percentage of stenosis decreased from 86% to 11%. The mean trans-stenotic gradient was reduced from 41 to 11 mm Hg. The results suggest that in patients whose condition is stable, PTCA performed a few days after thrombolysis is a valuable alternative to more aggressive treatment with immediate PTCA.
Gagnon
R M
RM
Department of Medicine, University of Montreal, Notre-Dame Hospital.
Morissette
M
M
Laramée
P
P
Dumont
G
G
Sestier
F
F
Leclerc
G
G
Goudreau
E
E
D000368:Aged; D000800:Angioplasty, Balloon; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000628:therapy*; D011379:Prognosis; D011446:Prospective Studies; D012008:Recurrence; D013300:Streptokinase / Q000008:administration & dosage*; D013997:Time Factors; D014654:Vascular Patency
D013300:Streptokinase