title: Kinetoplast DNA from Trypanosoma vivax and T. congolense.
abstract: We have analysed kinetoplast DNA (kDNA) of the African trypanosomes Trypanosoma vivax and T. congolense. The maxi-circles from these organisms resemble those of T. brucei in size, but only to a limited extent in sequence as judged from restriction enzyme digests and DNA X DNA hybridization. The kDNA networks of T. vivax have three distinguishing features: they contain the highest maxi-circle concentration of any kDNA (at least twice that of T. brucei); they contain the smallest mini-circles (465 bp) yet found thus far and the width of the kDNA nucleoid in thin sections is correspondingly small (55 nm against 91 nm for T. brucei); they contain a substantial fraction of mini-circle dimers.
authors.forename: P
authors.initials: P
authors.lastname: Borst
authors.forename: F
authors.initials: F
authors.lastname: Fase-Fowler
authors.forename: P J
authors.initials: PJ
authors.lastname: Weijers
authors.forename: J D
authors.initials: JD
authors.lastname: Barry
authors.forename: L
authors.initials: L
authors.lastname: Tetley
authors.forename: K
authors.initials: K
authors.lastname: Vickerman
mesh_terms: D000818:Animals; D004270:DNA, Circular / Q000032:analysis*; D018105:DNA, Kinetoplast; D004587:Electrophoresis, Agar Gel; D014345:Trypanosoma / Q000032:analysis* / Q000648:ultrastructure; D014348:Trypanosoma congolense / Q000032:analysis* / Q000648:ultrastructure
chemical_list: D004270:DNA, Circular; D018105:DNA, Kinetoplast