Polyoma virus-induced hemangiomas in grafts of visceral yolk sac and of embryos.
The development of hemangiomas in grafts of visceral yolk sac and embryos after in vitro infection with polyoma virus is described. These hemangiomas were shown to be positive for the polyoma tumor-specific transplantation antigen(s) and to develop as well in recipient virgin as in pregnant rats. In grafts of fetal skin or gut infected with polyoma virus neoplastic transformation was never observed.
Lu
Y L
YL
Sobis
H
H
van Hove
L
L
Vandeputte
M
M
D000818:Animals; D000951:Antigens, Neoplasm / Q000032:analysis; D004624:Embryo Transfer; D005260:Female; D006391:Hemangioma / Q000209:etiology / Q000276:immunology* / Q000473:pathology; D006649:Histocompatibility Antigens / Q000032:analysis; D011120:Polyomavirus / Q000276:immunology; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D014412:Tumor Virus Infections / Q000276:immunology* / Q000473:pathology; D015017:Yolk Sac / Q000637:transplantation*
D000951:Antigens, Neoplasm; D006649:Histocompatibility Antigens