title: Antibodies and natural immunity.
abstract: Natural antibody has been proposed as a mediator of T-independent (natural) resistance to tumors and microbial pathogens. In this article, it is argued that the "priming" of the B cell repertoire by ubiquitous microorganisms and autoantigens results in natural antibody production and this response offers a survival advantage for the host as a consequence of the participation of these antibodies in natural resistance.
authors.forename: A H
authors.initials: AH
authors.lastname: Greenberg
mesh_terms: D000906:Antibodies / Q000276:immunology*; D001402:B-Lymphocytes / Q000276:immunology; D017977:Deltaretrovirus / Q000276:immunology; D006561:Herpes Simplex / Q000276:immunology; D006801:Humans; D007113:Immunity, Innate; D009369:Neoplasms / Q000276:immunology; D012192:Retroviridae Infections / Q000276:immunology; D018139:Simplexvirus / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D000906:Antibodies