[The role of suppressor cells in congenital influenza infection in mice].
Young mice with congenital influenza infection have lower immune responsiveness of lymphocytes to nonspecific mitogens and influenza virus antigens. Lymphocytes of such animals inhibit proliferation of normal lymphoid cells activated with concanavalin A and immune lymphocytes activated with influenza virus antigens. It is assumed that in congenital influenza infection one of the possible mechanisms of immunosuppression in mice is the activation of suppressor T-cells.
Mirchink
E P
EP
Pronin
A V
AV
Zuev
V A
VA
Deeva
A V
AV
D000818:Animals; D000937:Antigen-Antibody Reactions; D000956:Antigens, Viral / Q000276:immunology; D003208:Concanavalin A / Q000494:pharmacology; D009980:Influenza A virus / Q000276:immunology; D008213:Lymphocyte Activation / Q000187:drug effects; D051379:Mice; D008810:Mice, Inbred C57BL; D009976:Orthomyxoviridae Infections / Q000151:congenital* / Q000276:immunology; D012897:Slow Virus Diseases / Q000151:congenital / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000187:drug effects / Q000276:immunology*
D000956:Antigens, Viral; D003208:Concanavalin A
Rol' supressornykh kletok pri vrozhdennoĭ gippoznoĭ infektsii u mysheĭ.