Cerebrospinal fluid flow studied with gated magnetic resonance imaging during the various parts of the cardiac cycle.
The pulsatile movement of cerebrospinal fluid (CSF) through the Sylvian aqueduct has been studied in two normal volunteers. A standard magnetic resonance scanner was used as well as a routine spin echo sequence. Series of ECG-gated axial images were obtained perpendicular to the long axis of the Sylvian aqueduct. Previously it has been demonstrated by flow phantom experiments that the phase information can be used to obtain a linear relation between phase and flow velocity. By multiplying the CSF flow velocity by the cross-sectional area of the aqueduct of Sylvius obtained in each image, the CSF flow variation during the cardiac cycle could be demonstrated and measured.
Bergstrand
G
G
Department of Neuroradiology, Karolinska Sjukhuset, Stockholm, Sweden.
Nordell
B
B
Ståhlberg
F
F
Ericsson
A
A
Bergström
M
M
Hemmingsson
A
A
Sperber
G
G
Thuomas
K A
KA
Jung
B
B
D002555:Cerebrospinal Fluid / Q000502:physiology*; D004562:Electrocardiography; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D009200:Myocardial Contraction