[Bronchiolitis obliterans with cryptogenetic-like organizing pneumonia. Demonstration of gastro-esophageal reflux in 5 cases].
Gastro-oesophageal reflux was demonstrated in 5 cases of bronchiolitis obliterans with apparently cryptogenetic organizing pneumonia. In addition, one patient had hiatus hernia and another, oesophageal diverticulum. In 4 patients, after failure of prolonged antibiotic therapy, medical or surgical treatment of the gastro-oesophageal reflux resulted in regression of the clinical and radiological signs of pulmonary lesions. The cure thus obtained persisted throughout a follow-up period of 2 months to 8 years. Gastro-oesophageal reflux therefore could be one of the causes of apparently cryptogenetic bronchiolitis obliterans with organizing pneumonia, and all patients with this respiratory disease should be investigated for gastro-oesophageal reflux.
Sadoun
D
D
Service de Pneumologie, Hôpital Avicenne, Bobigny.
Valeyre
D
D
Cargill
J
J
Volter
F
F
Amouroux
J
J
Battesti
J P
JP
D000368:Aged; D001989:Bronchiolitis Obliterans / Q000209:etiology* / Q000503:physiopathology; D001992:Bronchoalveolar Lavage Fluid / Q000032:analysis; D001999:Bronchoscopy; D005260:Female; D005500:Follow-Up Studies; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000628:therapy; D006801:Humans; D008875:Middle Aged; D011014:Pneumonia / Q000209:etiology* / Q000503:physiopathology
Bronchiolite oblitérante avec pneumonie en voie d'organisation en apparence cryptogénétique. Mise en évidence d'un reflux gastro-oesophagien dans 5 cas.