Chemical synthesis of a gene for somatomedin C.
A synthetic gene for somatomedin C, a human growth factor, has been assembled by a single ligation of 23 oligodeoxyribonucleotides, which were chemically synthesized by an improved solid phase phosphotriester method.
Sproat
B S
BS
Gait
M J
MJ
D002851:Chromatography, High Pressure Liquid; D004247:DNA / Q000138:chemical synthesis*; D004262:DNA Restriction Enzymes / Q000378:metabolism; D006801:Humans; D007334:Insulin-Like Growth Factor I; D009838:Oligodeoxyribonucleotides / Q000096:biosynthesis; D013002:Somatomedins / Q000235:genetics*
D009838:Oligodeoxyribonucleotides; D013002:Somatomedins; D007334:Insulin-Like Growth Factor I; D004247:DNA; D004262:DNA Restriction Enzymes