[Photoallergic and allergic contact eczema caused by dibenzoylmethane compounds and other sunscreening agents].
Dibenzoylmethanes are widely used in Europe in UV-A-absorbing sunscreens. We report on 21 patients with (photo)allergic contact dermatitis from 4-isopropyl-dibenzoylmethane. Six subjects revealed, in addition, (photo)allergic reactions to 4-tert.butyl-4'-methoxy-dibenzoylmethane, seven to 3-(4-methylbenzylidene)-camphor, two to 2-phenyl-benzimidazole-5-sulfonic acid and one to 2-phenyl-5-methylbenzoxazole. Allergic contact dermatitis from 2-phenyl-benzimidazole-5-sulfonic acid has not been reported previously. The relevance of sunscreens as a cause of (photo-)allergic contact dermatitis is discussed.
Schauder
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Universitäts-Hautklinik Göttingen.
Ippen
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D000293:Adolescent; D000328:Adult; D000368:Aged; D001565:Benzoates / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D010787:Photosensitivity Disorders / Q000139:chemically induced*; D013329:Structure-Activity Relationship; D013473:Sunscreening Agents / Q000009:adverse effects*
D001565:Benzoates; D013473:Sunscreening Agents
Photoallergisches und allegisches Kontaktekzem durch Dibenzoylmethan-Verbindungen und andere Lichtschutzfilter.