On the specificity of the immunoglobulin G produced by chickens experimentally infected with Marek's disease virus.
In chickens experimentally infected with Marek's Disease virus (MDV) an increased amount of immunoglobulin G is produced. Using a technique of quantitative crossed immunoelectrophoresis it has been shown, that 70% of this immunoglobulin G is non-specific. Only 18% could be absorbed with MDV strain CPRL VII-infected chicken kidney cells, and only 5% with MDV-induced lymphoblastoid cells of the MDCC-MSB1 cell line. It is hypothesized that the production the unspecific immunoglobulin G is caused by a polyclonal stimulation of B-cells.
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D000818:Animals; D000918:Antibody Specificity; D002645:Chickens / Q000276:immunology*; D005260:Female; D008381:Herpesvirus 2, Gallid / Q000276:immunology*; D007074:Immunoglobulin G / Q000302:isolation & purification*; D007158:Immunologic Techniques; D008380:Marek Disease / Q000276:immunology*; D011200:Poultry
D007074:Immunoglobulin G