title: Anti-mosquito antibodies and their effects on feeding, fecundity and mortality of Aedes aegypti.
abstract: Anti-mosquito antibodies, produced in mice inoculated with mosquito homogenates or exposed to mosquito bites, reacted with a variety of mosquito antigens including muscle, gut, fat body and nervous tissue; those in anti-mosquito bite sera reacted solely with salivary glands. Mosquitoes fed on restrained immunized mice showed a significant increase in mortality correlated to both the titre and specificity of the anti-mosquito antibodies ingested. No changes in their fecundity or feeding success were noted. Mosquitoes exposed to unrestrained immunized mice or mosquito-bitten mice, however, showed a significant reduction in feeding success, possibly reflecting enhanced host grooming.
authors.affiliation: Entomology Department, London School of Hygiene and Tropical Medicine.
authors.forename: P R
authors.initials: PR
authors.lastname: Hatfield
mesh_terms: D000330:Aedes / Q000276:immunology*; D000818:Animals; D000906:Antibodies / Q000097:blood / Q000276:immunology*; D000941:Antigens / Q000276:immunology; D005247:Feeding Behavior; D005260:Female; D005298:Fertility; D007150:Immunohistochemistry; D051379:Mice
chemical_list: D000906:Antibodies; D000941:Antigens