Respiration during sleep in Huntington's chorea.
In view of recent reports on lower brainstem dysfunction in Huntington's chorea, we studied respiration during sleep in 12 patients with Huntington's chorea (HC) and in controls. There were no statistically significant differences between patients and controls with respect to apnea periods, respiratory frequency and time elapsed between minimal and maximal value of the respiratory curve. No statistically significant differences in respiratory variability were observed between patients and controls. In the present study, no indication was found for dysfunction of lower brainstem structures involved in respiration in HC.
Bollen
E L
EL
Department of Neurology, University Hospital Leiden, The Netherlands.
Den Heijer
J C
JC
Ponsioen
C
C
Kramer
C
C
Van der Velde
E A
EA
Van Dijk
J G
JG
Roos
R A
RA
Kamphuisen
H A
HA
Buruma
O J
OJ
D000328:Adult; D001933:Brain Stem / Q000503:physiopathology; D005260:Female; D006801:Humans; D006816:Huntington Disease / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012119:Respiration; D012890:Sleep / Q000502:physiology*; D012894:Sleep Stages / Q000502:physiology