[Thrombolysis and myocardial infarct].
Thrombolytic therapy in acute myocardial infarction is able to recanalize thrombotic occluded infarct arteries in about 35 to 90%. The results depend on the thrombolytic agent and the route of administration (i.c., i.v.). Successful recanalization causes a reduction of hospital- and one year mortality and reduction of the infarct size in a close correlation to duration of ischemic pain at the beginning of thrombolysis. Significant residual stenoses persist in about 80 to 90% after successful reperfusion. In these patients, PTCA can be performed with high success rates and with a low incidence of complications. Successful PTCA is associated with a reduction of reinfarction and further improvement of left ventricular function. Thus, the value of thrombolysis in acute myocardial infarction in patients with pain duration shorter than 3 to 4 hours is established. The value and optimal point of time for performing PTCA after thrombolysis remains to be defined.
Leisch
F
F
I. Medizinischen Abteilung, Allgemeinen Krankenhauses der Stadt Linz.
D000800:Angioplasty, Balloon; D003131:Combined Modality Therapy; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006801:Humans; D009203:Myocardial Infarction / Q000188:drug therapy*
D005343:Fibrinolytic Agents
Thrombolyse und Myokardinfarkt).