title: Re-evaluation of "frontal deafferentation" studies on the regulation of ACTH secretion in the light of CRF immunohistology.
abstract: Frontal afferents to the medial basal hypothalamus of the rat were interrupted by a Halász knife, and 4 weeks later the brains were processed for immunostaining of CRF-fibers. It was found that such intervention saves most of the CRF immunoreactive fibers of the paraventriculo-infundibular tract. Some of the conflicting results of earlier deafferentation studies are discussed on the basis of CRF immunohistology.
authors.forename: I
authors.initials: I
authors.lastname: Lengvári
authors.forename: Z
authors.initials: Z
authors.lastname: Liposits
authors.forename: S
authors.initials: S
authors.lastname: Vigh
authors.forename: A V
authors.initials: AV
authors.lastname: Schally
authors.forename: B
authors.initials: B
authors.lastname: Flerkó
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D000818:Animals; D001923:Brain Chemistry; D003346:Corticotropin-Releasing Hormone / Q000032:analysis*; D006651:Histocytochemistry; D007033:Hypothalamus, Middle / Q000502:physiology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D000324:Adrenocorticotropic Hormone; D003346:Corticotropin-Releasing Hormone