title: Plasma atrial natriuretic polypeptide concentrations during and after reversion of paroxysmal supraventricular tachycardias.
abstract: Plasma concentrations of immunoreactive atrial natriuretic polypeptide were raised in 22 of 23 patients with paroxysmal supraventricular tachycardia and in all seven patients with atrial flutter. Plasma concentrations of atrial natriuretic polypeptide rose soon after the onset of supraventricular tachycardia. A sample taken 30 minutes after reversion to sinus rhythm (pharmacological or non-pharmacological) showed a significant fall in 19 of the 23 patients with paroxysmal supraventricular tachycardia and all seven patients with atrial flutter. Because atrial natriuretic polypeptide has powerful natriuretic and diuretic properties, an increase may contribute considerably to the polyuria that is often associated with episodes of supraventricular tachycardia.
authors.affiliation: Department of Medicine, Flinders Medical Centre, South Australia.
authors.forename: J R
authors.initials: JR
authors.lastname: Oliver
authors.forename: N
authors.initials: N
authors.lastname: Twidale
authors.forename: C
authors.initials: C
authors.lastname: Lakin
authors.forename: M
authors.initials: M
authors.lastname: Cain
authors.forename: A M
authors.initials: AM
authors.lastname: Tonkin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001281:Atrial Fibrillation / Q000097:blood; D001282:Atrial Flutter / Q000097:blood; D009320:Atrial Natriuretic Factor / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay / Q000379:methods; D013617:Tachycardia, Supraventricular / Q000097:blood*; D013997:Time Factors
chemical_list: D009320:Atrial Natriuretic Factor