Allergic dermatoses and respiratory diseases from reactive dyes.
5 cases of occupational eczema, urticaria and respiratory disease from reactive dyes, occurring during 1977-1987, are reported. The patients, 4 men and 1 woman, were 24-52 years old when examined. They had been working in dye houses or textile plants, and had been exposed to reactive dyes for 8 months to 4 years before symptoms developed. Only 1 of the patients has been able to continue in the same occupation. On patch testing, the 4 patients with eczema reacted positively to 9 commercial dye powders. 2 patients reacted to the same dye, Remazol Schwarz B. On scratch and/or prick testing, the 2 patients who also had respiratory symptoms and/or urticaria reacted positively to the same dyes as on patch testing. The 5th patient, who had urticaria and respiratory symptoms, reacted positively to a dye, Remazol Gold Gelb RNL, but the patch test with that dye was negative. None of the patients was patch-test-positive to para-phenylenediamine (PPD) or to textile dye allergens in a series of organic dyes. Thus, the series of organic dyes has little value in the screening of allergy to reactive dyes. A 1% pet. dilution of commercial dye powder for patch testing and the same concentration in distilled water for prick testing seem to be suitable for the screening of allergy to reactive dyes.
Estlander
T
T
Department of Occupational Medicine, Institute of Occupational Health, Helsinki, Finland.
D000328:Adult; D001249:Asthma / Q000139:chemically induced*; D001985:Bronchial Provocation Tests; D002855:Chromatography, Thin Layer; D004396:Coloring Agents / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000276:immunology*; D009783:Dermatitis, Occupational / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009299:Nasal Provocation Tests; D010328:Patch Tests / Q000379:methods; D011852:Radioallergosorbent Test; D012220:Rhinitis / Q000139:chemically induced*
D004396:Coloring Agents