Plasma neuropeptide Y and atrial natriuretic peptide concentrations in man.
1. In order to examine the concentration of neuropeptide Y-like immunoreactivity (NPY-LI) and atrial natriuretic peptide (ANP) in the circulation in man, blood was sampled from the iliac vein, the inferior vena cava, the superior vena cava, the pulmonary artery and the femoral artery in 13 patients undergoing cardiac catheterization. 2. Plasma NPY-LI levels were similar at all points sampled and no arteriovenous differences were found. Plasma ANP concentration in the pulmonary artery was greater than in peripheral venous blood but there was a strong correlation between the two. 3. The concentration of NPY-LI and ANP in peripheral venous blood reflects central venous and arterial concentrations.
Russell
A E
AE
Department of Medicine, Flinders Medical Centre, Adelaide, South Australia.
Aylward
P E
PE
Smith
S A
SA
Cain
M D
MD
McRitchie
R J
RJ
Chalmers
J P
JP
D000328:Adult; D000368:Aged; D009320:Atrial Natriuretic Factor / Q000097:blood*; D006328:Cardiac Catheterization; D003327:Coronary Disease / Q000097:blood; D005260:Female; D005263:Femoral Artery; D005268:Femoral Vein; D006801:Humans; D008297:Male; D008875:Middle Aged; D009478:Neuropeptide Y / Q000097:blood*; D011651:Pulmonary Artery; D014684:Venae Cavae
D009478:Neuropeptide Y; D009320:Atrial Natriuretic Factor