Iopamidol 150. A low iodine content non-ionic water-soluble contrast medium for CT myelocisternography.
Results of a clinical trial in CT myelocisternography performed with a new reduced concentration of iopamidol (150 mg I/ml) are reported. This compound is characterized by very low osmolality and osmotic pressure close to those of blood and CSF. Thirty patients were examined. Before, during and after the procedure pulse rate and blood pressure were recorded, EEG was taken and neurologic examination performed. After the examination no alteration in these parameters was recorded. The demonstration of the subarachnoid space and related structures was invariably adequate for diagnosis. In no case was a repeat study using a higher concentration of contrast medium needed. Mild reactions occurred only in three patients (10%). The authors conclude that iopamidol 150, owing to its safety and good imaging capacity, is useful in CT imaging of the subarachnoid space.
Beltramello
A
A
Department of Neuroradiology, Borgo Trento Hospital, Verona, Italy.
Leonardi
M
M
Biasizzo
E
E
Piscitelli
G
G
D000293:Adolescent; D000328:Adult; D000368:Aged; D001921:Brain / Q000000981:diagnostic imaging*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007479:Iopamidol / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009192:Myelography; D014057:Tomography, X-Ray Computed
D007479:Iopamidol