Structure of the porcine thyrotropin receptor: a 200 kilodalton glycoprotein heterocomplex.
We have determined that the porcine thyroidal TSH receptor is a glycoprotein heterotetramer composed of two Mr approximately 35,000 (epsilon) covalently linked subunits which interact noncovalently with two copies of delta (Mr 66,000) chains.
Islam
M N
MN
Farid
N R
NR
D000818:Animals; D002462:Cell Membrane / Q000032:analysis; D055598:Chemical Phenomena; D002621:Chemistry; D002845:Chromatography; D004220:Disulfides; D004586:Electrophoresis; D006023:Glycoproteins; D046911:Macromolecular Substances; D008970:Molecular Weight; D010446:Peptide Fragments; D011956:Receptors, Cell Surface / Q000302:isolation & purification / Q000378:metabolism; D011989:Receptors, Thyrotropin; D013552:Swine; D013961:Thyroid Gland / Q000032:analysis*; D013972:Thyrotropin / Q000378:metabolism
D004220:Disulfides; D006023:Glycoproteins; D046911:Macromolecular Substances; D010446:Peptide Fragments; D011956:Receptors, Cell Surface; D011989:Receptors, Thyrotropin; D013972:Thyrotropin