Hyperprolactinemia in primary adrenocortical insufficiency.
A patient with primary adrenocortical deficiency presented with galactorrhea and hyperprolactinemia, in addition to the usual characteristic symptoms of adrenal insufficiency. With steroid replacement therapy, PRL levels returned to normal, with resumption of normal ovulatory cycles; and the patient became pregnant. Primary adrenocortical deficiency should be considered as one of the very rare causes in the differential diagnosis of hyperprolactinemia.
Kelver
M E
ME
Nagamani
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M
D000005:Abdomen; D000303:Adrenal Cortex Diseases / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D000568:Amenorrhea / Q000209:etiology; D005260:Female; D005687:Galactorrhea / Q000209:etiology; D006801:Humans; D010146:Pain / Q000503:physiopathology; D011247:Pregnancy; D011388:Prolactin / Q000097:blood*; D013972:Thyrotropin / Q000097:blood; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology
D000305:Adrenal Cortex Hormones; D013973:Thyrotropin-Releasing Hormone; D000324:Adrenocorticotropic Hormone; D011388:Prolactin; D013972:Thyrotropin