title: [Detection of macrophage activity in the blood and synovia of chronic polyarthritis patients using an activated oxygen microassay].
abstract: A microassay was developed for the estimation of macrophage (M phi)-activation by released activated oxygen. From peripheral blood or synovia M phi are isolated. O-2 which is released by activated M phi is photometrically detected by cytochrome c reduction. Differences in O-2-production do not exist between monocytes of rheumatoid arthritis patients and controls. In contrast synovial M phi from rheumatoid arthritis patients show increased levels of O-2-production.
authors.forename: E
authors.initials: E
authors.lastname: Schmitz
authors.forename: H
authors.initials: H
authors.lastname: Warnatz
mesh_terms: D001172:Arthritis, Rheumatoid / Q000276:immunology*; D003574:Cytochrome c Group / Q000378:metabolism; D006801:Humans; D008264:Macrophages / Q000276:immunology*; D009000:Monocytes / Q000276:immunology; D010100:Oxygen / Q000378:metabolism*; D013582:Synovial Fluid / Q000276:immunology*
chemical_list: D003574:Cytochrome c Group; D010100:Oxygen
vernacular_title: Nachweis der Makrophagenaktivität in Blut und Synovia von chronisch Polyarthritis-Kranken mittels eines aktivierten Sauerstoff-Mikroassays.