Antibodies to adult T-cell leukemia virus (ATLV/HTLV-I) in AIDS patients and people at risk of AIDS in Germany.
A total of 2048 serum samples from Germany were examined for antibodies to adult T-cell leukemia virus (ATLV) structural polypeptides with an enzyme-linked immuno sorbent assay (ELISA) and confirmative immuno precipitation. The origin of the sera samples was: 850 samples taken for virological or protozoal diagnosis; 626 samples from male homosexuals, about 20% of whom had lymphadenopathy syndrome; 164 from hemophiliacs; 184 were from multiple transfused, mostly dialysis patients; 9 from intravenous drug abusers; 182 from suspected cases of acquired immuno deficiency syndrome (AIDS) and 33 from AIDS-patients. In none of these sera did we detect antibodies to ATLV, except in the serum of one patient who had been on hemodialysis for over 11 years. Obviously infection with ATLV or a serologically related agent is very rare in our country and an association with AIDS could not be observed.
Hunsmann
G
G
Schneider
J
J
Bayer
H
H
Berthold
H
H
Schimpf
K
K
Kabisch
H
H
Ritter
K
K
Bienzle
U
U
Schmitz
H
H
Kern
P
P
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000302:isolation & purification*; D017977:Deltaretrovirus / Q000276:immunology*; D005860:Germany, West; D006467:Hemophilia A / Q000276:immunology; D006716:Homosexuality; D006801:Humans; D008297:Male; D008875:Middle Aged; D065227:Transfusion Reaction
D000914:Antibodies, Viral