Pruritus ani: could it be malignant?
The management of extramammary perianal Paget's disease should include a careful search for an associated carcinoma in the pelvic viscera by means of proctoscopy and x-ray. Such local malignancies as Bowen's disease, which may be pigmented and multifocal in this region, and invasive squamous cell carcinoma may first manifest themselves as pruritus ani.
Powell
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FC
Perry
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HO
D001005:Anus Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010145:Paget Disease, Extramammary / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D011538:Pruritus Ani / Q000175:diagnosis* / Q000209:etiology