Differences in the processing of secreted glycoprotein A induced by Marek's disease virus and herpesvirus of turkeys.
The steps from the precursor to the processed forms of a secreted glycoprotein (gA) of Marek's disease virus (MDV) and of herpesvirus of turkeys (HVT) were examined by two-dimensional gel electrophoresis of immunoprecipitates from the cell lysate and medium of infected cultures with monoclonal antibodies. Differences between MDV- and HVT-gA were particularly observed in isoelectric points of the glycosylated or unglycosylated precursor forms.
Ikuta
K
K
Nakajima
K
K
Ueda
S
S
Kato
S
S
Hirai
K
K
D000818:Animals; D002478:Cells, Cultured; D002642:Chick Embryo; D004591:Electrophoresis, Polyacrylamide Gel; D006023:Glycoproteins / Q000032:analysis / Q000378:metabolism*; D006564:Herpesviridae / Q000378:metabolism*; D008381:Herpesvirus 2, Gallid / Q000378:metabolism*; D007526:Isoelectric Point; D011498:Protein Precursors / Q000378:metabolism*; D011499:Protein Processing, Post-Translational; D014422:Turkeys / Q000382:microbiology; D014764:Viral Proteins / Q000032:analysis / Q000378:metabolism*
D006023:Glycoproteins; D011498:Protein Precursors; D014764:Viral Proteins