R1767, an example of the evolution of resistance plasmids.
The Salmonella R-factor system R1767 undergoes frequent rearrangement of its plasmid components. The flux of genetic material within this plasmid system depends on a combination of illegitimate and homologous recombination. The presence of several copies of IS160 and two multiresistance transposons, Tn2410 and Tn2411, are substantial reasons for the observed variations.
Nies
B A
BA
Meyer
J F
JF
Kratz
J
J
Wiedemann
B
B
D005075:Biological Evolution; D004251:DNA Transposable Elements; D004352:Drug Resistance, Microbial; D009693:Nucleic Acid Hybridization; D010641:Phenotype; D011815:R Factors; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics*
D004251:DNA Transposable Elements