Anaesthetic management of glucagonoma.
Alpha cell tumours of the pancreatic islets of Langerhans are rare. The glucagonoma syndrome is caused by excess glucagon secretion from such a tumour. Physiologically, glucagon is important in the control of the homeostatis of glucose and certain amino acids. Pharmacologically, it has been used to treat heart failure. Problems with both glucose homeostasis and myocardial function could, therefore, theoretically be anticipated following resection of a glucagonoma. This paper describes the peri-operative management of such a case, where, despite measured changes in glucagon, no problems of this nature were encountered.
Nicoll
J M
JM
Catling
S J
SJ
D007516:Adenoma, Islet Cell / Q000601:surgery*; D000328:Adult; D000768:Anesthesia, General; D001786:Blood Glucose / Q000032:analysis; D005260:Female; D005934:Glucagon / Q000097:blood; D005935:Glucagonoma / Q000601:surgery*; D006801:Humans; D007432:Intraoperative Period; D010190:Pancreatic Neoplasms / Q000601:surgery*; D010191:Pancreatic Polypeptide / Q000097:blood; D011184:Postoperative Period
D001786:Blood Glucose; D010191:Pancreatic Polypeptide; D005934:Glucagon