title: Multi-dimensional analyses of behavior in mice treated with naltrexone.
abstract: The effects of naltrexone on the behavior in mice were investigated by using a multi-dimensional behavioral analyser. Within 15 min following observation, naltrexone preferentially suppressed the linear locomotion at the 10 and 30 mg/kg doses. The results suggest that naltrexone selectively disrupts the linear locomotion without affecting other behaviors in mice.
authors.forename: M
authors.initials: M
authors.lastname: Ukai
authors.forename: T
authors.initials: T
authors.lastname: Kameyama
mesh_terms: D000818:Animals; D001921:Brain / Q000187:drug effects; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009043:Motor Activity / Q000187:drug effects*; D009270:Naloxone / Q000031:analogs & derivatives*; D009271:Naltrexone / Q000494:pharmacology*; D011957:Receptors, Opioid / Q000187:drug effects
chemical_list: D011957:Receptors, Opioid; D009270:Naloxone; D009271:Naltrexone