title: [Prevention of disorders of cardiac contractility with nicotinamide in adriblastin -related damage].
abstract: Pretreatment with 20 mg/kg nicotinamide 3 days prior to a single intraperitoneal 6 mg/kg adriblastin injection, followed by repeated injections every second days for 1 week, prevented cardiac contractility disorders in adriblastin-treated rats, while their cardiac contractility was less prone to hypoxic depression and recovered better at subsequent reoxygenation.
authors.forename: A N
authors.initials: AN
authors.lastname: Nurmukhambetov
authors.forename: T A
authors.initials: TA
authors.lastname: Riabtseva
mesh_terms: D000818:Animals; D009202:Cardiomyopathies / Q000139:chemically induced / Q000188:drug therapy*; D004317:Doxorubicin / Q000009:adverse effects*; D006333:Heart Failure / Q000209:etiology / Q000517:prevention & control*; D000860:Hypoxia / Q000139:chemically induced / Q000188:drug therapy*; D009200:Myocardial Contraction / Q000187:drug effects*; D009536:Niacinamide / Q000627:therapeutic use*; D051381:Rats
chemical_list: D009536:Niacinamide; D004317:Doxorubicin
vernacular_title: Preduprezhdenie narusheniĭ sokratitel'noĭ funktsii serdtsa pri adriblastinovom povrezhdenii s pomoshch'iu nikotinamida.