Modeling AIDS and its treatment with immunostimulation.
A mathematical model of AIDS and its response to treatment with immunostimulation therapy is introduced. It correctly predicted the response of an AIDS patient to hyperimmunization with inactivated polio vaccine for a period of four months, indicating that this benign modality will offset the clinical effects of HIV-1 infection for almost a year.
Allen
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Biomedical Sciences Division, Algorithms, Incorporated, Northridge, California 91325.
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology / Q000628:therapy*; D000328:Adult; D004334:Drug Administration Schedule; D006801:Humans; D007114:Immunization / Q000379:methods*; D008297:Male; D008954:Models, Biological; D011054:Poliovirus Vaccine, Inactivated / Q000627:therapeutic use*; D011237:Predictive Value of Tests; D012074:Remission Induction; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology
D011054:Poliovirus Vaccine, Inactivated