Left ventricular hypertrophy differences between male and female renovascular hypertensive rats.
In a previous study we demonstrated ventricular hypertrophy in male but not in female sinoaortic denervated rats. To evaluate a possible sexual influence on ventricular hypertrophy of other models for experimental hypertension, we studied two-kidney one clip and one-kidney one clip Goldblatt hypertension. The results showed left ventricular hypertrophy in male but not in female two-kidney one clip groups, despite the same arterial hypertension level in both groups. In the one-kidney one clip groups, left ventricular hypertrophy was greater in male than in female rats. The results indicate a sexual influence in ventricular hypertrophy when the arterial renovascular hypertension level is moderate.
Cabral
A M
AM
Departamento de Ciências Fisiológicas, UFES, Vitória, Brasil.
Antonio
A
A
Moyses
M R
MR
Vasquez
E C
EC
D000818:Animals; D001794:Blood Pressure; D001835:Body Weight; D006332:Cardiomegaly / Q000209:etiology*; D005260:Female; D012739:Gonadal Steroid Hormones / Q000502:physiology*; D006339:Heart Rate; D006978:Hypertension, Renovascular / Q000503:physiopathology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012727:Sex Characteristics
D012739:Gonadal Steroid Hormones