title: N alpha-dimethylcoprogens. Three novel trihydroxamate siderophores from pathogenic fungi.
abstract: Three novel siderophores have been isolated from a highly pathogenic strain of Alternaria longipes (ATCC 26293). The compounds are N alpha-dimethylated analogs of coprogen, neocoprogen I and isoneocoprogen I. Structures of the compounds have been determined by 1H- and 13C-NMR, fast-atom-bombardment (FAB) mass spectroscopy and partial hydrolysis. One of the new compounds, N alpha-dimethylcoprogen, is also produced, as the major siderophore, in another fungus, Fusarium dimerum.
authors.affiliation: Department of Chemistry, University of Oklahoma, Norman 73019.
authors.forename: M A
authors.initials: MA
authors.lastname: Jalal
authors.forename: S K
authors.initials: SK
authors.lastname: Love
authors.forename: D
authors.initials: D
authors.lastname: van der Helm
mesh_terms: D000528:Alternaria / Q000032:analysis* / Q000472:pathogenicity; D005670:Fusarium / Q000032:analysis* / Q000472:pathogenicity; D006877:Hydroxamic Acids / Q000302:isolation & purification*; D007502:Iron Chelating Agents / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D017262:Siderophores
chemical_list: D006877:Hydroxamic Acids; D007502:Iron Chelating Agents; D017262:Siderophores; C065890:N(alpha)-dimethylneocoprogen; C065891:N(alpha)-dimethylisoneocoprogen I; C065863:N(alpha)-dimethylcoprogen