title: Paramagnetic enhancement of cerebral lesions with gadolinium-DTPA.
abstract: Magnetic resonance imaging (MRI) was performed on 30 patients with cerebral symptoms before and after intravenous gadolinium-DTPA (Gd-DTPA) administration. T1 and T2 weighted images were obtained in all patients. Fifty abnormalities were found in 27 patients. The post-contrast images revealed lesions not seen on pre-contrast scans in 6 patients. Also, the post-contrast images showed a change in morphology of the lesions in 15 that provided additional information for assessing the abnormality. The Gd-DTPA did not obscure any of the lesions seen on pre-contrast scans. Gd-DTPA improves conspicuity, helps characterize and delineate the extent of lesions and increases the sensitivity for detection of cerebral abnormalities.
authors.affiliation: Department of Radiology, University of California School of Medicine, San Diego.
authors.forename: J R
authors.initials: JR
authors.lastname: Hesselink
authors.forename: W M
authors.initials: WM
authors.lastname: Dunn
authors.forename: M E
authors.initials: ME
authors.lastname: Healy
authors.forename: P
authors.initials: P
authors.lastname: Hajek
authors.forename: L
authors.initials: L
authors.lastname: Baker
authors.forename: F J
authors.initials: FJ
authors.lastname: Brahme
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001927:Brain Diseases / Q000175:diagnosis*; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA