[Allergic contact dermatitis to prednisolone-21-trimethyl acetate].
A 64-year-old female patient developed periorbital eczema after eye treatment with a corticoid ointment. Epicutaneous tests with the effective component as well as with other ingredients of the ointment and suspected substances revealed a delayed hypersensitivity to prednisolone-21-trimethyl acetate, neomycin, cobalt, and cetyl alcohol. We did not observe any cross-reactions to other corticoids, not even to the closely related prednisolone-21-monoacetate. To the best of our knowledge, allergic contact dermatitis to prednisolone-21-trimethyl acetate has not been described in the literature so far.
Schmoll
M
M
Universitäts-Hautklinik Hamburg.
Hausen
B M
BM
D001762:Blepharitis / Q000139:chemically induced*; D003875:Drug Eruptions / Q000209:etiology*; D005141:Eyelid Diseases / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010328:Patch Tests; D011239:Prednisolone / Q000009:adverse effects / Q000031:analogs & derivatives*
C002442:mecortolon; D011239:Prednisolone
Allergische Kontaktdermatitis auf Prednisolon-21-trimethylacetat.