Elastase, collagenase and the radial elastic properties of arteries.
Studies were performed on 203 pairs of dog carotid arteries subjected to unidirectional radial compression. Treatment with 80 U/ml purified elastase for 90 min decreased radial stress, but treatment with 640 U/ml collagenase for 90 min did not. These data suggest that elastin, but not collagen, contributes to wall resistance to radial compression.
Dobrin
P B
PB
Gley
W C
WC
D000818:Animals; D002339:Carotid Arteries / Q000502:physiology*; D003094:Collagen / Q000502:physiology; D004285:Dogs; D004548:Elasticity; D004549:Elastin / Q000502:physiology; D066298:In Vitro Techniques; D003012:Microbial Collagenase; D010196:Pancreatic Elastase; D013314:Stress, Mechanical; D013379:Substrate Specificity
D003094:Collagen; D004549:Elastin; D010196:Pancreatic Elastase; D003012:Microbial Collagenase