title: Hypothyroidism in Down's syndrome.
abstract: Fifty-five adult Down's syndrome subjects resident at Northgate Hospital were screened for the presence of thyroid dysfunction. Approximately 50% of the subjects had clinical features suggestive of hypothyroidism, sufficient to require thyroid-function tests. Twenty-two per cent of the total suffered from some degree of hypothyroidism, and 16% had positive antibodies to thyroid tissue.
authors.affiliation: Northgate Hospital, Northumberland, Scotland.
authors.forename: C
authors.initials: C
authors.lastname: Mani
mesh_terms: D000328:Adult; D000368:Aged; D000906:Antibodies / Q000032:analysis; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000150:complications*; D008297:Male; D008875:Middle Aged; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000276:immunology
chemical_list: D000906:Antibodies