title: [Herpes simplex infection in the newborn infant].
abstract: A case of neonatal Herpes simplex infection is being described, which was diagnosed clinically as well as serologically. It concerns a child, which was born after 35 weeks of gestation. Two days after the delivery the mother showed typically efflorescences of Herpes simplex infection in the abdominal region. On the fifth day after birth the child showed a vesico-bullous exanthema beginning on the head and spreading out on breast and back. On day 14th a serious sepsis-like pattern of the disease with respiratory insufficiency and encephalitic symptoms could be seen. Treatment with Vidarabinphosphat and Acyclovir-Natrium was without definite success. At the age of five months the child showed a pseudobulbar-paralysis with tetra-spasticity. The cranial computer-tomography demonstrated a distinct hydrocephalus e vacuo and the electroencephalography registered only sporadic brain activity.
authors.forename: H
authors.initials: H
authors.lastname: Sobczak
authors.forename: W
authors.initials: W
authors.lastname: Gebauer
authors.forename: E
authors.initials: E
authors.lastname: Schütz
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis; D010244:Bulbar Palsy, Progressive / Q000175:diagnosis; D004660:Encephalitis / Q000175:diagnosis; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005500:Follow-Up Studies; D006558:Herpes Genitalis / Q000175:diagnosis; D006561:Herpes Simplex / Q000151:congenital* / Q000175:diagnosis; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis; D018139:Simplexvirus / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: Herpes simplex-Infektion beim Neugeborenen.