title: Diabetic retinopathy: II. Assessment of severity and progression from fluorescein angiograms.
abstract: A quantitative method for assessing the severity of retinopathy from fluorescein angiograms was applied to a group of patients starting continuous subcutaneous insulin infusion. There was a highly significant correlation between the area of nonperfusion as measured in the 20 degrees field centered on the right macula, and the mean retinopathy score derived by a standard method from a color retinal photographic survey. In those subjects who deteriorated more, there was an increase in the nonperfused areas, whereas the foveal avascular zone remained unchanged.
authors.affiliation: Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London, England.
authors.forename: M A
authors.initials: MA
authors.lastname: Sleightholm
authors.forename: S J
authors.initials: SJ
authors.lastname: Aldington
authors.forename: J
authors.initials: J
authors.lastname: Arnold
authors.forename: E M
authors.initials: EM
authors.lastname: Kohner
mesh_terms: D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology; D003930:Diabetic Retinopathy / Q000175:diagnosis* / Q000503:physiopathology; D005451:Fluorescein Angiography; D006801:Humans; D012160:Retina / Q000098:blood supply