[Role of the cholesterol of platelet membranes in disorders of their structuro-functional condition in angina pectoris patients].
A study of 80 anginal patients showed their platelet molar cholesterol/phospholipid ratios, platelet membrane microviscosity, membrane release of calcium and fatty acids, and platelet aggregation capacity to be elevated. It is assumed that excessive platelet cholesterol has a significant effect on platelet aggregation, that is mediated by the intraplatelet processes examined, in anginal patients.
D000328:Adult; D000787:Angina Pectoris / Q000097:blood*; D001792:Blood Platelets / Q000032:analysis* / Q000502:physiology; D002462:Cell Membrane / Q000032:analysis* / Q000502:physiology; D002784:Cholesterol / Q000097:blood*; D004578:Electron Spin Resonance Spectroscopy; D005230:Fatty Acids, Nonesterified / Q000097:blood; D006801:Humans; D008297:Male; D008563:Membrane Lipids / Q000032:analysis*; D008875:Middle Aged; D010743:Phospholipids / Q000097:blood; D010974:Platelet Aggregation
D005230:Fatty Acids, Nonesterified; D008563:Membrane Lipids; D010743:Phospholipids; D002784:Cholesterol
Rol' kholesterina membran trombotsitov v narushenii ikh strukturno-funktsional'nogo sostoianiia u bol'nykh so stenokardieĭ.