Cochlear and retrocochlear immune-mediated inner ear disorders. Pathogenetic mechanisms and diagnostic tools.
Three different forms of immune-mediated sensorineural hearing loss are described. The pathogeneses of these three cases with severe audiovestibular deficits are completely different. To make an appropriate diagnosis remains a dilemma. Autoimmunity plays a certain role, but is not always present. Vascular and neural tissue can become involved. Immune-mediated forms of sensorineural hearing loss can be of cochlear or retrocochlear origin.
D000293:Adolescent; D000328:Adult; D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000188:drug therapy; D003638:Deafness / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D003639:Hearing Loss, Sudden / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010523:Peripheral Nervous System Diseases / Q000209:etiology; D014657:Vasculitis / Q000175:diagnosis / Q000188:drug therapy