A peculiar phenomenon: increased polypeptide hormone binding (receptor accumulation) in the midbody region.
Fluorescein-labeled polypeptide hormones, hormone analogons and fragments were selectively bound by the midbody, which bound neither con-A, nor the fluorescent stain in itself. This experimental observation suggests an accumulation in the midbody region of non-glycosilated hormone receptors, apparently to present a receptor pool for the separating daughter cells.
D002455:Cell Division; D002460:Cell Line; D002462:Cell Membrane / Q000378:metabolism*; D016650:Fluorescein-5-isothiocyanate; D005452:Fluoresceins; D006728:Hormones / Q000378:metabolism*; D007328:Insulin / Q000378:metabolism; D008099:Liver; D008856:Microscopy, Fluorescence; D008938:Mitosis; D011956:Receptors, Cell Surface / Q000378:metabolism*; D013861:Thiocyanates
D005452:Fluoresceins; D006728:Hormones; D007328:Insulin; D011956:Receptors, Cell Surface; D013861:Thiocyanates; D016650:Fluorescein-5-isothiocyanate