title: Malignant fibrous histiocytoma of bone.
abstract: Malignant fibrous histiocytoma of bone is a highly malignant neoplasm similar to that found in soft tissues. It accounts for at least 5% of all primary malignant bone tumors. The majority of lesions are primary, but some arise in preexisting benign lesions. Definitive diagnosis is made on histologic examination, a storiform arrangement of spindly tumor cells being the classic finding. Radical resection combined with preoperative and postoperative chemotherapy is the treatment of choice.
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography