Steroid secretion by a lipoid cell tumor causing virilization and its diagnosis with computerized tomography.
Presented is the case of a virilized woman with a lipoid cell tumor of the ovary localized by computerized tomography. The major secretory products of the tumor were testosterone and estradiol; the production of androgens was responsible for the clinical features and hindered the effects of estrogens. Elevated levels of estradiol indicated important ovarian aromatase activity as reflected by large ovarian-peripheral venous gradients.
D000328:Adult; D000728:Androgens / Q000378:metabolism*; D004967:Estrogens / Q000378:metabolism*; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism*; D018310:Sertoli-Leydig Cell Tumor / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism*; D013739:Testosterone / Q000378:metabolism; D014057:Tomography, X-Ray Computed; D014770:Virilism / Q000209:etiology*
D000728:Androgens; D004967:Estrogens; D013739:Testosterone