title: Dysplastic nevus syndrome: association with multiple primary neoplasms.
abstract: A 65-year-old white man with dysplastic nevus syndrome is presented. The patient also developed an extramammary Paget's disease of the scrotum, two malignant melanomas of the skin of the arm and abdomen, two squamous cell carcinomas in the mouth, and several benign tumors such as lentigo maligna, dermatofibroma, and a cavernous hemangioma. Besides the well-established tendency of patients with the dysplastic nevus syndrome to develop malignant melanomas of the skin, their possible propensity to develop other primary malignant neoplasms is discussed.
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D006801:Humans; D008297:Male; D008545:Melanoma / Q000150:complications / Q000473:pathology*; D009062:Mouth Neoplasms / Q000473:pathology*; D009378:Neoplasms, Multiple Primary; D009508:Nevus, Pigmented / Q000150:complications / Q000473:pathology*; D010145:Paget Disease, Extramammary / Q000473:pathology*; D012611:Scrotum; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology*; D013577:Syndrome