title: Effect of diet on intestinal xylose absorption in dogs.
abstract: The absorption of xylose at different levels of the intestine was compared in five dogs receiving diets containing either wheat bran, polyethylene particles (PE), or horse-bean hulls. The absorption was determined by serial collection of the interstitial fluid (ISF) in different parts of the small intestine and colon, and blood concentration after the administration of D-xylose as a solution (0.5 g/kg body weight) into the duodenal bulb. Xylose was mostly absorbed from the duodenum, and its concentration in the duodenal ISF and in plasma was reduced on a diet containing fiber, irrespective of the nature of fiber. In contrast, a negative linear relation between the mean retention time of digesta in the small intestine and the amount of xylose absorbed by duodenum was evidenced (r = -0.843). The results indicate that changes in transit linked to the presence of fiber in a diet are a major operative factor in the rate of carbohydrate absorption. They suggest that the absorption can be affected by a relatively minor change in the intestinal transit of digesta.
mesh_terms: D000818:Animals; D004043:Dietary Fiber / Q000494:pharmacology*; D004285:Dogs; D004386:Duodenum / Q000378:metabolism; D005110:Extracellular Space / Q000378:metabolism; D007887:Fabaceae; D005769:Gastrointestinal Motility; D007408:Intestinal Absorption; D010946:Plants, Medicinal; D011095:Polyethylenes / Q000494:pharmacology; D014867:Water; D014994:Xylose / Q000097:blood / Q000378:metabolism
chemical_list: D004043:Dietary Fiber; D011095:Polyethylenes; D014867:Water; D014994:Xylose