[Nucleotide sequences in DNA showing preferential binding with distamycin A and acridine derivatives].
The specificity of DNA X dye binding was studied. Antibiotic distamycin A was bound most strongly to the DNA sequences composed of three or more neighboring A X T pairs. Acrichin and 7-aminoacrichin proved to be weak specific inhibitors binding predominantly within the A X T regions.
D000609:Aminoacridines / Q000378:metabolism*; D001483:Base Sequence; D001665:Binding Sites; D004247:DNA / Q000378:metabolism*; D004262:DNA Restriction Enzymes; D004214:Distamycins / Q000378:metabolism*; D066298:In Vitro Techniques; D011758:Pyrroles / Q000378:metabolism*
D000609:Aminoacridines; D004214:Distamycins; D011758:Pyrroles; C030000:stallimycin; D004247:DNA; D004262:DNA Restriction Enzymes
Nukleotidnye posledovatel'nosti v DNK, predpochtitel'nye dlia sviazyvaniia distamitsina A i proizvodnykh akridina.