The possible potassium involvement in the modulation of the long-term trophic action of ACTH on the rat adrenal zona fasciculata.
The effects of chronic potassium loading on the zona fasciculata of the rat adrenal cortex were investigated. It was found that potassium stimulates the growth and the steroidogenic capacity of the zona fasciculata presumably by enhancing the trophic effects of ACTH.
D000302:Adrenal Cortex / Q000254:growth & development* / Q000378:metabolism / Q000648:ultrastructure; D000324:Adrenocorticotropic Hormone / Q000502:physiology*; D000818:Animals; D003345:Corticosterone / Q000097:blood; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D008297:Male; D008928:Mitochondria / Q000648:ultrastructure; D011188:Potassium / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains
D000324:Adrenocorticotropic Hormone; D011188:Potassium; D003345:Corticosterone