Biological effects of the superoxide radical.
Can the superoxide radical exert deleterious effects independent of participating with H2O2 in the production of the hydroxyl radical? Examination of the superoxide-related literature reveals data suggesting an affirmative answer to this question.
D000818:Animals; D002374:Catalase / Q000378:metabolism; D002384:Catalysis; D002630:Chemotactic Factors / Q000096:biosynthesis; D004912:Erythrocytes / Q000378:metabolism; D005293:Ferritins / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000378:metabolism; D006454:Hemoglobins / Q000378:metabolism; D007249:Inflammation / Q000378:metabolism; D007527:Isoenzymes / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008054:Lipid Peroxides / Q000502:physiology; D008168:Lung / Q000187:drug effects; D008264:Macrophages / Q000187:drug effects; D008970:Molecular Weight; D009504:Neutrophils / Q000502:physiology; D010084:Oxidation-Reduction; D010100:Oxygen / Q000633:toxicity; D010269:Paraquat / Q000633:toxicity; D010477:Perfusion; D009195:Peroxidase; D010544:Peroxidases / Q000378:metabolism; D010944:Plants; D012441:Saccharomyces cerevisiae / Q000378:metabolism; D012771:Shock, Hemorrhagic / Q000378:metabolism; D013234:Stem Cells / Q000187:drug effects; D013482:Superoxide Dismutase / Q000378:metabolism; D013481:Superoxides / Q000502:physiology* / Q000633:toxicity; D014174:Transketolase / Q000378:metabolism
D002630:Chemotactic Factors; D006454:Hemoglobins; D007527:Isoenzymes; D008054:Lipid Peroxides; D013481:Superoxides; D005293:Ferritins; D007770:L-Lactate Dehydrogenase; D010544:Peroxidases; C038109:pseudocatalase; D002374:Catalase; D009195:Peroxidase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D014174:Transketolase; D010269:Paraquat; D010100:Oxygen