title: [Effect of cross-linking agents on electron transport and proton transfer in the mitochondrial respiratory chain].
abstract: The effect of protein cross-linkage on proton translocation and electron transport in mitochondria respiratory chain was studied. Dimethylsuberimidate (1 mM) or dicyclohexyl carbodiimide (50 g/ml) inhibit proton translocation with concomitant stimulation of respiration. It is concluded that the definite level of dynamic mobility of proteins is needed for proton translocation.
mesh_terms: D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D003432:Cross-Linking Reagents / Q000494:pharmacology*; D004579:Electron Transport / Q000187:drug effects; D066298:In Vitro Techniques; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D010084:Oxidation-Reduction; D011522:Protons; D051381:Rats
chemical_list: D003432:Cross-Linking Reagents; D011522:Protons
vernacular_title: Vliianie sshivaiushchikh agentov na transport élektronov i perenos protonov v dykhatel'noĭ tsepi mitokhondriĭ.