Mistletoe lectin I binding sites on the synaptosomes of the rat cerebral cortex.
By means of combined lectinological and immunological methods were demonstrated mistletoe lectin I binding sites on rat cerebral cortex synaptosomes. The mistletoe lectin I binds specifically D-galactose. Galactosyl residues were established on the junctional and nonjunctional synaptosomal membrane, on the synaptic vesicles, mitochondria and on myelin contamination. The relative number of mistletoe lectin I receptors per unit area of synaptosomal membrane was calculated.
D000818:Animals; D002540:Cerebral Cortex / Q000378:metabolism*; D005293:Ferritins / Q000032:analysis; D008854:Microscopy, Electron; D028321:Plant Preparations; D010940:Plant Proteins; D051381:Rats; D011975:Receptors, Mitogen / Q000032:analysis*; D017981:Receptors, Neurotransmitter / Q000032:analysis*; D054790:Ribosome Inactivating Proteins, Type 2; D013574:Synaptosomes / Q000378:metabolism* / Q000648:ultrastructure; D014118:Toxins, Biological / Q000378:metabolism*
D028321:Plant Preparations; D010940:Plant Proteins; D011975:Receptors, Mitogen; D017981:Receptors, Neurotransmitter; D054790:Ribosome Inactivating Proteins, Type 2; D014118:Toxins, Biological; C009674:ribosome inactivating protein, Viscum; D005293:Ferritins