Lactic acidosis with small cell carcinoma. Rapid response to chemotherapy.
A patient presented with widespread small cell carcinoma, abnormalities on liver function tests, and rapidly progressive lactic acidosis. The acidosis was totally corrected following chemotherapy. Prompt treatment in tumor-associated lactic acidosis may significantly prolong survival.
D000138:Acidosis / Q000188:drug therapy / Q000209:etiology*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D018288:Carcinoma, Small Cell / Q000150:complications* / Q000188:drug therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D007773:Lactates / Q000378:metabolism*; D008175:Lung Neoplasms / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D014750:Vincristine / Q000008:administration & dosage
D007773:Lactates; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide