title: [Mechanism of inhibition of cardiac activity by the stellate ganglion in the cat and guinea pig].
abstract: In acute and chronic experiments on guinea pigs (43) and cats (49), the stellate ganglion inhibition of the heart activity was revealed to be a consequence of excitation of the vagus cholinergic fibers converging with branches of the stellate ganglion on their route to the heart. Alpha-adrenorecptors were shown to exert no noticeable effect on the heart work. Neither the hypothesis of switching of the sympathetic fibers over to intracardiac cholinergic neurons, nor the hypothesis of the cholinergic link in the mechanism of catecholamines release by the sympathetic nerve terminals, were confirmed. The Dayle principle stating that one neuron exerts its efferent affect by means of one transmitter, seems to be justified.
mesh_terms: D000818:Animals; D002415:Cats; D004558:Electric Stimulation; D006168:Guinea Pigs; D006321:Heart / Q000294:innervation*; D006339:Heart Rate; D011942:Receptors, Adrenergic, alpha / Q000502:physiology; D011943:Receptors, Adrenergic, beta / Q000502:physiology; D011950:Receptors, Cholinergic / Q000502:physiology; D013233:Stellate Ganglion / Q000033:anatomy & histology / Q000502:physiology*; D014630:Vagus Nerve / Q000033:anatomy & histology / Q000502:physiology*
chemical_list: D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D011950:Receptors, Cholinergic
vernacular_title: Mekhanizm tormozheniia deiatel'nosti serdtsa zvezdchatym gangliem u koshek i morskikh svinok.