Triple antibiotic spray application to umbilical cords.
A trial in 402 newborns demonstrated that application of 'Tribiotic' spray either as a single dose at birth or repeated daily resulted in a significant reduction of umbilical cord infections compared with no antibiotic application. 'Tribiotic' spray was well tolerated but led to delayed cord separation.
D000433:1-Propanol / Q000627:therapeutic use; D000336:Aerosols; D001414:Bacitracin / Q000008:administration & dosage / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000517:prevention & control*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D006801:Humans; D007231:Infant, Newborn; D009355:Neomycin / Q000008:administration & dosage / Q000627:therapeutic use*; D011112:Polymyxin B / Q000008:administration & dosage / Q000627:therapeutic use*; D011113:Polymyxins / Q000627:therapeutic use*; D013203:Staphylococcal Infections / Q000188:drug therapy; D013997:Time Factors; D014470:Umbilical Cord
D000336:Aerosols; D004338:Drug Combinations; D011113:Polymyxins; D001414:Bacitracin; D000433:1-Propanol; D009355:Neomycin; D011112:Polymyxin B