[Vaccination of adults against hepatitis B virus in a tropical African environment (Ivory Coast). Study of results according to the serologic status toward the virus].
A total of 103 volunteers, from 18 to 55 years of age have received subcutaneous injection of the hevac B Pasteur 5 micrograms vaccine: one injection a month during three months and one booster injection after one year. The study of the anti-HBs reaction of the subjects, with regard to the serologicale status to the hepatitis B virus before inoculation, has shown that only 78.8% of the subjects, who are only positive towards the anti-HBc antibody, will develop an anti-HBs response of primary type with a relatively low value. On the contrary, all anti-HBc and/or anti-HBs subjects, who were positive before inoculation, react with relatively high anti-HBs value immediately after the first injection. 93.3% of the seronegative subjects before inoculation will develop an anti-HBs seroconversion after the complete inoculation procedure.
D000293:Adolescent; D000328:Adult; D007560:Cote d'Ivoire; D006509:Hepatitis B / Q000517:prevention & control*; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006515:Hepatitis B virus / Q000276:immunology*; D006801:Humans; D008875:Middle Aged; D012703:Serotyping; D014611:Vaccination
D006514:Hepatitis B Surface Antigens
Vaccination des adultes contre le virus de l'hépatite B en milieu tropical africain (Côte-d'Ivoire). Etude des resultats selon le statut sérologique vis-à-vis du virus.