[Human T-cell leukemia (lymphoma) virus (HTLV-I) antibodies in Danish patients with cutaneous T-cell lymphoma].
HTLV-I antibodies were found in 10 out of 68 patients with cutaneous T-cell lymphoma (14%). HTLV antibodies were found in the earliest pre-diagnostic stage [Mycosis fungoides I (MF I), histologically non-diagnostic] as well as in the later stages (MF-III), where tumour cells are histologically apparent and the skin lesions have progressed from the plaque stage to the tumour stage. Of 4 patients with lymphomatoid papulosis, only 1 had positive HTLV antibody sera. Sequential studies of 6 patients demonstrated that the presence of HTLV-I antibodies was independent of the clinical remission - relapse stages in these patients. The present results show that HTLV-I or a related virus is found in Denmark and probably more widely distributed than was previously thought.
D000914:Antibodies, Viral / Q000032:analysis*; D017977:Deltaretrovirus / Q000276:immunology; D003718:Denmark; D004797:Enzyme-Linked Immunosorbent Assay; D015483:HIV Antibodies; D006801:Humans; D008223:Lymphoma / Q000276:immunology*; D008230:Lymphomatoid Granulomatosis / Q000276:immunology; D009182:Mycosis Fungoides / Q000276:immunology; D012192:Retroviridae Infections / Q000276:immunology*; D012751:Sezary Syndrome / Q000276:immunology; D012878:Skin Neoplasms / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
D000914:Antibodies, Viral; D015483:HIV Antibodies
Humane T-Zellenleukämie (Lymphom)-Virus (HTLV-I)-Antikörper bei dänischen Patienten mit kutanem T-Zellenlymphom.