Chemotherapy of synovial cell sarcoma in a dog.
A synovial cell sarcoma of the tarsus in a 6-year-old dog was treated with doxorubicin HCl and cyclophosphamide. The tumor regressed after treatment. There was no recurrence 3 years after initiation of treatment. Previously, synovial cell sarcoma has not been reported to be responsive to chemotherapeutic agents, and the treatment of choice has been amputation.
D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy / Q000662:veterinary*; D003520:Cyclophosphamide / Q000008:administration & dosage; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004317:Doxorubicin / Q000008:administration & dosage; D005500:Follow-Up Studies; D006614:Hindlimb; D008297:Male; D013584:Sarcoma, Synovial / Q000662:veterinary*; D013643:Tarsus, Animal
D004317:Doxorubicin; D003520:Cyclophosphamide