Bilateral and synchronous squamous cell carcinoma of the cervix in a patient with uterus didelphys.
Reported herein is the case of a 30-year-old white woman who had a congenitally double uterus with two cervixes (uterus didelphys). Each cervix was diffusely involved by squamous cell carcinoma in situ that had progressed to a microinvasive stage of the same depth (0.8 mm) on each side. This coincidence was the more remarkable because it had taken place synchronously. A transmissible coital factor of a viral nature, ie, human papillomavirus infection, was suggested by the presence of koilocytotic atypia in both uterine cervixes.
D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000473:pathology; D002584:Cervix Uteri / Q000002:abnormalities*; D005260:Female; D006801:Humans; D027383:Papillomaviridae; D014412:Tumor Virus Infections / Q000150:complications / Q000473:pathology; D002583:Uterine Cervical Neoplasms / Q000150:complications* / Q000473:pathology; D014599:Uterus / Q000002:abnormalities*