title: Isolation of a retrovirus and a herpesvirus from a captive California sea lion.
abstract: A non-oncogenic retrovirus was isolated from an explanted skin biopsy from a captive California sea lion (Zalophus californianus) with a history of recurring skin lesions. The morphology of the viral particles in electron photomicrographs was characteristic of a foamy virus, a retrovirus in the subfamily Spumavirinae. Viral cytopathic effects consistent with foamy virus infection were observed in subsequent explants of skin and lymph nodes and co-cultivated peripheral blood leukocytes. The sea lion with the persistent foamy virus infection later died from pericarditis caused by Pasteurella multocida. A herpesvirus was isolated from explants of lung.
mesh_terms: D000818:Animals; D010872:Caniformia / Q000382:microbiology*; D005260:Female; D006564:Herpesviridae / Q000302:isolation & purification*; D007962:Leukocytes / Q000382:microbiology; D008198:Lymph Nodes / Q000382:microbiology; D008297:Male; D010325:Pasteurella / Q000302:isolation & purification; D010326:Pasteurella Infections / Q000382:microbiology / Q000662:veterinary; D010493:Pericarditis / Q000382:microbiology / Q000662:veterinary; D012190:Retroviridae / Q000302:isolation & purification*; D046070:Sea Lions / Q000382:microbiology*; D012867:Skin / Q000382:microbiology* / Q000473:pathology; D012874:Skin Diseases, Infectious / Q000382:microbiology / Q000662:veterinary*; D016092:Spumavirus / Q000302:isolation & purification*