[Monoclonal antibodies in pharmacology].
The paper outlines technology of monoclonal antibody manufacture. Pharmacological applications of monoclonal antibodies are considered. The list is given of produced by the late 1984 stable hybridomas to various receptors and some proteins being of interest to pharmacology. The possibility of using monoclonal antibodies as carriers for drug transport is discussed.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000302:isolation & purification / Q000627:therapeutic use; D000915:Antibody Affinity; D000918:Antibody Specificity; D001666:Binding Sites, Antibody; D002459:Cell Fusion; D002846:Chromatography, Affinity; D006801:Humans; D006825:Hybridomas / Q000276:immunology; D007114:Immunization / Q000379:methods; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008024:Ligands; D004364:Pharmaceutical Preparations / Q000032:analysis; D014677:Pharmaceutical Vehicles; D051381:Rats; D011956:Receptors, Cell Surface / Q000032:analysis / Q000276:immunology; D011950:Receptors, Cholinergic / Q000032:analysis / Q000276:immunology; D013329:Structure-Activity Relationship
D000911:Antibodies, Monoclonal; D007166:Immunosuppressive Agents; D008024:Ligands; D004364:Pharmaceutical Preparations; D014677:Pharmaceutical Vehicles; D011956:Receptors, Cell Surface; D011950:Receptors, Cholinergic
Monoklonal'nye antitela v farmakologii.