Congenital obstructive uropathy and nodular renal blastema.
The occurrence of nodular renal blastema and renal dysplasia was determined in a retrospective study of 75 cases of congenital obstructive uropathy. Nodular renal blastema was present in 3 upper pole nephrectomy specimens removed as a consequence of nonfunction owing to ectopic ureterocele; none was dysplastic. A more differentiated type of nodular renal blastema was present in 3 other total nephrectomy specimens, bilateral involvement in a case of posterior urethral valves and unilateral nodular renal blastema associated with ureteral atresia. This subset of differentiated nodular renal blastema was associated with renal dysplasia.
D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007668:Kidney / Q000002:abnormalities* / Q000473:pathology; D007680:Kidney Neoplasms / Q000151:congenital* / Q000473:pathology; D008297:Male; D012189:Retrospective Studies; D014513:Ureter / Q000002:abnormalities; D014517:Ureteral Obstruction / Q000151:congenital*; D014518:Ureterocele / Q000151:congenital*; D014521:Urethra / Q000002:abnormalities; D009396:Wilms Tumor / Q000151:congenital* / Q000473:pathology