[Adrenocorticotrophic function of the pituitary and immune response in the rat].
The effect of hypophysis adrenocorticotropic function on the immune response to the ram erythrocytes in rats was studied after hypophysectomy or centragenous dexametasone blockade; the humoral immune response was more obviously activated in animals fed with dexametasone whereas indices of the cellular immunity: the delayed hypersensitivity response (DHR)--were more obvious in hypophysectomised animals. The T-cell populations are normally much more suppressed with glycocorticoids than the cells participating in humoral immune response.
D000324:Adrenocorticotropic Hormone / Q000502:physiology*; D000818:Animals; D003907:Dexamethasone / Q000494:pharmacology; D005938:Glucocorticoids / Q000502:physiology; D006388:Hemagglutinins / Q000096:biosynthesis; D006968:Hypersensitivity, Delayed / Q000503:physiopathology; D007016:Hypophysectomy; D007109:Immunity; D007111:Immunity, Cellular; D007074:Immunoglobulin G / Q000096:biosynthesis; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D005938:Glucocorticoids; D006388:Hemagglutinins; D007074:Immunoglobulin G; D003907:Dexamethasone; D000324:Adrenocorticotropic Hormone
Adrenokortikotropnaia funktsiia gipofiza i immunnyĭ otvet u krys.