title: Ultracytochemical study of the stria vascularis of the guinea pig cochlea.
abstract: The localization of the K-NPPase, ALPase and Mg-ATPase activities in the stria vascularis of the guinea pig cochlea was ultracytochemically studied. The K-NPPase reflecting the Na-K-ATPase activity was localized on the cytoplasmic side of the deeply infolded basolateral plasma membrane of the marginal cells. On the other hand, activities of ALPase and Mg-ATPase were found in the intercellular spaces between the marginal and the intermediate or the basal cells. The surface of the stria vascularis facing to endolymph showed only the Mg-ATPase activity. The ALPase activity localized also around the capillaries. The mechanism of the K and Na transport was discussed.
mesh_terms: D009597:4-Nitrophenylphosphatase / Q000378:metabolism*; D000469:Alkaline Phosphatase / Q000378:metabolism*; D000818:Animals; D017301:Ca(2+) Mg(2+)-ATPase / Q000378:metabolism*; D002462:Cell Membrane / Q000648:ultrastructure; D003051:Cochlea / Q000033:anatomy & histology*; D003593:Cytoplasm / Q000648:ultrastructure; D006168:Guinea Pigs; D008854:Microscopy, Electron; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism*; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*; D013316:Stria Vascularis / Q000033:anatomy & histology* / Q000201:enzymology
chemical_list: D000469:Alkaline Phosphatase; D010744:Phosphoric Monoester Hydrolases; D009597:4-Nitrophenylphosphatase; D017301:Ca(2+) Mg(2+)-ATPase; D000254:Sodium-Potassium-Exchanging ATPase