[Immunohistochemical localization of S-100 protein in granular cell myoblastoma].
Three cases of granular cell myoblastoma have been studied in order to determine the presence and distribution of the S-100 specific protein in the neoplastic cells, using immunocytochemical staining techniques, through the modified avidin-biotin method. Positive immunostaining was observed in the three cases studied. The comparative study of various control cases histogenetically originating from neuroectoderm (melanoma) and specifically from Schwann cells, as also the presence of strongly positive staining in Schwann cells of peripheral nerve fibres situated inside and outside the tumor, support the concept of the neurogenic origin of this interesting tumor.
D000008:Abdominal Neoplasms / Q000032:analysis* / Q000196:embryology; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D009363:Neoplasm Proteins / Q000032:analysis*; D009369:Neoplasms / Q000032:analysis; D009379:Neoplasms, Muscle Tissue / Q000032:analysis* / Q000196:embryology; D009380:Neoplasms, Nerve Tissue / Q000032:analysis / Q000196:embryology; D009418:S100 Proteins / Q000032:analysis*; D012878:Skin Neoplasms / Q000032:analysis* / Q000196:embryology; D014846:Vulvar Neoplasms / Q000032:analysis* / Q000196:embryology
D009363:Neoplasm Proteins; D009418:S100 Proteins
Localización inmunohistoquímica de la proteína S-100 en el mioblastoma de células granulares.