Primary central nervous system lymphoma related to Epstein-Barr virus in a patient with acquired immune deficiency syndrome.
The study of a patient suggested a relationship between Epstein-Barr virus infection and primary lymphoma of the central nervous system in the acquired immune deficiency syndrome. Deoxyribonucleic acid preparations from tumor tissue contained 30 to 100 copies of Epstein-Barr virus genome per cell when hybridized with a probe consisting of the Bam-HI K fragment of Epstein-Barr virus strain FF41. This hybridization study suggests that induction of this patient's central nervous system lymphoma was related to Epstein-Barr virus infection.
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D001932:Brain Neoplasms / Q000032:analysis / Q000150:complications*; D004279:DNA, Viral / Q000032:analysis; D004854:Herpesvirus 4, Human; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000032:analysis / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009778:Occipital Lobe; D014412:Tumor Virus Infections / Q000150:complications*
D004279:DNA, Viral