title: Myeloma, paraproteinemias, and the skin.
abstract: This review focuses on those systemic diseases or syndromes associated with monoclonal plasma cell disorders that may present with important cutaneous manifestations. Amyloidosis, POEMS syndrome, cutaneous plasmacytoma, xanthomas, benign hypergammaglobulinemic purpura of Waldenström, and scleromyxedema are emphasized.
mesh_terms: D000686:Amyloidosis / Q000473:pathology; D004700:Endocrine System Diseases / Q000473:pathology; D006099:Granuloma / Q000473:pathology; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008179:Lupus Erythematosus, Discoid / Q000473:pathology; D008297:Male; D009101:Multiple Myeloma / Q000150:complications*; D009230:Myxedema / Q000473:pathology; D010265:Paraproteinemias / Q000150:complications*; D010523:Peripheral Nervous System Diseases / Q000473:pathology; D010954:Plasmacytoma / Q000473:pathology; D011694:Purpura, Hyperglobulinemic / Q000473:pathology; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000209:etiology*; D012878:Skin Neoplasms / Q000473:pathology; D013577:Syndrome; D014973:Xanthomatosis
chemical_list: D007136:Immunoglobulins