Diagnosis of HTLV-III infection by ultrastructural examination of germinal centers in lymph node--a case report.
Serum from a patient suspected of having AIDS showed positive ELISA tests but the diagnostic p 41 band was absent and the p 24 band was barely discernible on a Western blot. Before another Western blot was performed lentivirions were detected between dendritic reticulum cells in a lymph node biopsy. It is suggested that samples of biopsies of lymph nodes from patients with or at risk for AIDS should be embedded in resin for future ultrastructural study if indicated.
D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis* / Q000473:pathology; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D001706:Biopsy; D003101:Collodion; D017977:Deltaretrovirus / Q000648:ultrastructure*; D004591:Electrophoresis, Polyacrylamide Gel; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006801:Humans; D008198:Lymph Nodes / Q000166:cytology / Q000473:pathology / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D010209:Paper; D012192:Retroviridae Infections / Q000175:diagnosis* / Q000473:pathology; D012191:Retroviridae Proteins / Q000276:immunology
D000914:Antibodies, Viral; D012191:Retroviridae Proteins; D003101:Collodion