[Cytomegalovirus hyperimmune globulin and cytomegalovirus-tested blood products--a pilot study in bone marrow graft recipients].
Nineteen bone marrow transplant recipients had cytomegalovirus prophylaxis using a commercial hyperimmune globulin. Seronegative donors were selected for blood component substitution. The incidence of seroconversion was 25%. One patient acquired fatal cytomegalovirus associated interstitial pneumonitis. The value of this combined cytomegalovirus prophylaxis in bone marrow transplant recipients in comparison to sole passive immunization is recommended to be the subject of a controlled trial.
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral; D001769:Blood / Q000382:microbiology*; D001803:Blood Transfusion / Q000379:methods*; D016026:Bone Marrow Transplantation; D003587:Cytomegalovirus / Q000276:immunology / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007116:Immunization, Passive; D008297:Male
D000914:Antibodies, Viral
CMV-Hyperimmunglobulin und CMV-getestete Blutprodukte--eine Pilotstudie bei Knochenmarktransplantatempfängern.