Principles of carrier catalysis elucidated by comparing two similar membrane translocators from mitochondria, the ADP/ATP carrier and the uncoupling protein.
D000244:Adenosine Diphosphate / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D002001:Adipose Tissue, Brown / Q000648:ultrastructure; D001278:Atractyloside / Q000031:analogs & derivatives / Q000378:metabolism; D001693:Biological Transport, Active; D001865:Bongkrekic Acid / Q000378:metabolism; D002352:Carrier Proteins; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004563:Electrochemistry; D006150:Guanine Nucleotides / Q000378:metabolism; D007292:Inosine Nucleotides / Q000378:metabolism; D007425:Intracellular Membranes / Q000378:metabolism; D007473:Ion Channels; D046911:Macromolecular Substances; D008565:Membrane Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism*; D008823:Micelles; D008928:Mitochondria / Q000378:metabolism*; D000226:Mitochondrial ADP, ATP Translocases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D024101:Mitochondrial Proteins; D009713:Nucleotidyltransferases / Q000378:metabolism*; D017830:Octoxynol; D011092:Polyethylene Glycols; D011487:Protein Conformation; D011522:Protons; D013816:Thermodynamics; D000071256:Uncoupling Protein 1
D002352:Carrier Proteins; D006150:Guanine Nucleotides; D007292:Inosine Nucleotides; D007473:Ion Channels; D046911:Macromolecular Substances; D008565:Membrane Proteins; D008823:Micelles; D024101:Mitochondrial Proteins; D011522:Protons; D000071256:Uncoupling Protein 1; D001865:Bongkrekic Acid; D001278:Atractyloside; D011092:Polyethylene Glycols; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D017830:Octoxynol; D000226:Mitochondrial ADP, ATP Translocases; D009713:Nucleotidyltransferases; C003853:carboxyatractyloside