[Augmentation by dilution of the effect of PVP iodine on poliomyelitis virus type I].
The influence of dilution of povidone-iodine solutions on virucidal activity against poliovirus type 1 was investigated. After exposure to different concentrations of povidone-iodine, the reduction in virus titer was determined after separating the antiseptic by gel filtration. Diluted preparations (0.5 and 0.25%) achieved a greater reduction in virus titer (10(5) in one hour) than the 5% stock solution (10(3)). Moreover, dilute solutions exhibited a faster virucidal activity.
D008826:Microbial Sensitivity Tests; D017955:Poliovirus / Q000187:drug effects*; D011205:Povidone / Q000031:analogs & derivatives*; D011206:Povidone-Iodine / Q000494:pharmacology*; D012996:Solutions
D012996:Solutions; D011206:Povidone-Iodine; D011205:Povidone
Augmentation par la dilution de l'activité de la PVP iodée sur le virus poliomyelitique type I.