The role of phospholipids in the binding of antimycin to yeast Complex III.
Treatment of yeast Complex III with hexane or repeated fractionation with ammonium sulfate-cholate abolishes the ability of antimycin to bind to the complex. Antimycin binding is partially restored by addition of phospholipids to the depleted complex; this action of phospholipids can be enhanced by including Q6 in the reconstitution mixture.
D000968:Antimycin A / Q000031:analogs & derivatives* / Q000378:metabolism; D002308:Cardiolipins / Q000494:pharmacology; D014450:Electron Transport Complex III / Q000378:metabolism*; D005453:Fluorescence; D010743:Phospholipids / Q000494:pharmacology*; D014451:Ubiquinone / Q000502:physiology
D002308:Cardiolipins; D010743:Phospholipids; C032456:antimycin; D014451:Ubiquinone; D000968:Antimycin A; D014450:Electron Transport Complex III