[Interrelation between the natural antioxidant content and lipid viscosity in normal organelle membranes].
Two systems regulating lipid peroxidation (LP) natural antioxidants and structural organization were studied in the liver mitochondria, microsomes and nuclear membranes, using chemiluminescent and spin labelling techniques. Mitochondrial lipids were most protected against LP and were characterized by the maximum content of effective antioxidants and high viscosity. Nuclear lipids were the least protected against the systems studied and had lower antioxidant efficiency and viscosity. Direct correlation between the content of natural antioxidants and lipid viscosity was established.
D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D004578:Electron Spin Resonance Spectroscopy; D007425:Intracellular Membranes / Q000378:metabolism*; D007700:Kinetics; D008051:Lipid Bilayers / Q000378:metabolism; D008054:Lipid Peroxides / Q000378:metabolism; D008099:Liver / Q000378:metabolism / Q000648:ultrastructure; D008163:Luminescent Measurements; D008563:Membrane Lipids / Q000378:metabolism*; D051379:Mice; D009940:Organoids / Q000378:metabolism*; D014783:Viscosity
D000975:Antioxidants; D008051:Lipid Bilayers; D008054:Lipid Peroxides; D008563:Membrane Lipids
Vzaimosviaz' mezhdu soderzhaniem prirodnykh antioksidantov i viazkost'iu lipidov v membranakh organell v norme.