title: Passive hemagglutination for cytomegalovirus antibody: specificity and stability of reagents.
abstract: Glutaraldehyde fixed red cells coated with CMV antigen were lyophilized in the presence of stabilizers such as glycerol, lactose, sorbitol and sucrose. These cells maintained their sensitivity for anti-CMV detection for at least 6 mth when held at 4 degrees C. Some rheumatoid factors containing sera react non-specifically with crude CMV antigen coated cells. The agglutinins in these sera could be effectively removed by adsorption with red cells coated with polymerized IgG.
mesh_terms: D000327:Adsorption; D000914:Antibodies, Viral / Q000032:analysis*; D000956:Antigens, Viral / Q000276:immunology*; D003587:Cytomegalovirus / Q000145:classification / Q000276:immunology*; D004912:Erythrocytes; D005189:False Positive Reactions; D005976:Glutaral; D005990:Glycerol; D006386:Hemagglutination Tests; D006801:Humans; D007074:Immunoglobulin G; D007785:Lactose; D012217:Rheumatoid Factor; D013012:Sorbitol; D013395:Sucrose
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral; D007074:Immunoglobulin G; D013012:Sorbitol; D013395:Sucrose; D012217:Rheumatoid Factor; D007785:Lactose; D005990:Glycerol; D005976:Glutaral