[Variations in serum kininase II activity in acute jaundice].
An assay of Kininase II activity in the serum of 92 jaundice patients revealed a significant difference between the group with viral hepatitis (268.48 +/- 70.93 U/ml), that with biliary obstructions (133.05 +/- 37.64 U/ml) and with cirrhosis (173.76 +/- 79.56 U/ml). The increase encountered in patients with medical jaundice correlates well with total bilirubinaemia but not with cytolysis enzymes. This suggests failed demolition of ACE by the hepatocyte during cellular stress.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001663:Bilirubin / Q000097:blood; D002779:Cholestasis / Q000150:complications / Q000175:diagnosis / Q000209:etiology; D004796:Clinical Enzyme Tests; D003937:Diagnosis, Differential; D005260:Female; D006525:Hepatitis, Viral, Human / Q000150:complications / Q000175:diagnosis; D006801:Humans; D007565:Jaundice / Q000175:diagnosis* / Q000209:etiology; D008103:Liver Cirrhosis / Q000150:complications / Q000175:diagnosis; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D007703:Peptidyl-Dipeptidase A / Q000097:blood*
D007703:Peptidyl-Dipeptidase A; D001663:Bilirubin
Variazioni dell'attività sierica kininasica II negli itteri acuti.