title: ADP-ribosyltransferase in isolated nuclei during the cell cycle of Physarum polycephalum.
abstract: ADP-ribosyltransferase was measured in isolated nuclei of Physarum polycephalum. Activity was determined with and without exogenous DNA and histones. During the synchronous cell cycle the activity measured with exogenous substrates exhibited a typical peak enzyme pattern with a maximum of activity in S-phase, whereas activity measured without exogenous substrates displayed a step enzyme pattern. Both activities doubled in each cell cycle.
mesh_terms: D002453:Cell Cycle; D002467:Cell Nucleus / Q000201:enzymology; D007399:Interphase; D009713:Nucleotidyltransferases / Q000378:metabolism*; D010804:Physarum / Q000166:cytology / Q000201:enzymology*; D011064:Poly Adenosine Diphosphate Ribose / Q000096:biosynthesis; D011065:Poly(ADP-ribose) Polymerases
chemical_list: D011064:Poly Adenosine Diphosphate Ribose; D011065:Poly(ADP-ribose) Polymerases; D009713:Nucleotidyltransferases