Triple extramammary Paget's disease. Immunohistochemical studies.
A 75-year-old man developed three lesions of Paget's disease which involved the pubic area and both axillae. Histologically, there was no invasion into the dermis in any of the three lesions. Various kinds of histochemical and immunohistochemical studies including those for carcinoembryonic antigen showed that both genital and axillary lesions were identical in nature. Cases with triple involvement of Paget's disease are thought to be extremely rare in the literature.
D000368:Aged; D000951:Antigens, Neoplasm / Q000032:analysis; D001365:Axilla / Q000473:pathology; D002272:Carcinoembryonic Antigen / Q000032:analysis; D006119:Groin / Q000473:pathology; D006801:Humans; D008297:Male; D010145:Paget Disease, Extramammary / Q000097:blood / Q000276:immunology / Q000473:pathology*; D012878:Skin Neoplasms / Q000097:blood / Q000276:immunology / Q000473:pathology*
D000951:Antigens, Neoplasm; D002272:Carcinoembryonic Antigen