title: The effect of root detoxification on human gingival fibroblasts.
abstract: Comparative growth or inhibition of growth of human gingival fibroblasts on experimental root surfaces was used to assess the efficacy in vitro of the Cavitron and Prophy-Jet. Six teeth with a hopeless periodontal prognosis, slated for prosthetic replacement, were extracted and sectioned into 12 specimens. Experimental specimens were instrumented with the Cavitron or Cavitron and Prophy-Jet. Four calculus-covered control specimens were not treated. Eight root specimens in fibroblast tissue culture were stained with 1.0% toluidine blue for determination of fibroblast viability after 48 hours. No fibroblast growth took place on calculus control specimens. Cavitron specimens showed light fibroblast growth and viability. Cavitron/Prophy-Jet specimens showed superior growth and vitality of fibroblasts.
mesh_terms: D000268:Adhesiveness; D001639:Bicarbonates / Q000008:administration & dosage; D002130:Calcium Phosphates / Q000008:administration & dosage; D002478:Cells, Cultured; D003777:Dental Prophylaxis / Q000295:instrumentation*; D004867:Equipment Design; D005347:Fibroblasts / Q000502:physiology*; D005881:Gingiva / Q000166:cytology*; D006801:Humans; D012964:Sodium / Q000008:administration & dosage; D017693:Sodium Bicarbonate; D013997:Time Factors; D014092:Tooth Root / Q000502:physiology*; D014464:Ultrasonic Therapy / Q000295:instrumentation
chemical_list: D001639:Bicarbonates; D002130:Calcium Phosphates; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; D017693:Sodium Bicarbonate; C020243:calcium phosphate; D012964:Sodium; C485829:calcium phosphate, dibasic, anhydrous