title: [cAMP and cGMP in the cerebrospinal fluid of patients with multiple sclerosis].
abstract: The authors studied the changes in cAMP and cGMP concentrations in the cerebrospinal fluid in 38 patients with multiple sclerosis. A statistically significant fall of cAMP was observed with a simultaneous rise of cGMP in the initial stage of the disease as compared with the control group. In the later course of the disease and development of various clinical forms of multiple sclerosis the pattern of these changes was not characteristic.
mesh_terms: D000293:Adolescent; D000328:Adult; D000242:Cyclic AMP / Q000134:cerebrospinal fluid*; D006152:Cyclic GMP / Q000134:cerebrospinal fluid*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid*; D013997:Time Factors
chemical_list: D000242:Cyclic AMP; D006152:Cyclic GMP
vernacular_title: cAMP i cGMP w płynie mózgowo-rdzeniowym u chorych na stwardnienie rozsiane.