[Structural analysis of alphoid DNA of primates. II. Evolution and possible origin of alphoid DNA of primates].
A computer analysis of human and primate alphoid DNA was performed. The number and localization of short inverted complete repeats within alphoid DNA dimers (but not monomers) remain conserved. Thus, in spite of high heterogeneity of the primary structure the conserved secondary structure of alphoid DNA might be functionally important. The analysis of internal periodicity of the monomeric sequences of human and primate alphoid DNA revealed its potential ancient sequence, that is a simple satellite DNA with a reiterated heptanucleotide TGAAAAA, which is suggested to be the ancestor of satellite DNase of rodents. The facts reported propose the ancient origin and possible functional role of alphoid-like DNA as a universal pericentromeric superfamily of DNA.
D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D004247:DNA / Q000235:genetics*; D004262:DNA Restriction Enzymes; D006801:Humans; D011323:Primates / Q000235:genetics*; D012091:Repetitive Sequences, Nucleic Acid; D013045:Species Specificity
D004247:DNA; D004262:DNA Restriction Enzymes
Strukturnyĭ analiz al'foidnoĭ DNK primatov. II. Evoliutsiia i vozmozhnoe proiskhozhdenie al'foidnoĭ DNK primatov.