Identification with monoclonal antibodies of virus-specific DNA-binding proteins in the nuclei of cells infected with three serotypes of Marek's disease virus-related viruses.
Two groups of virus-specific polypeptides were identified in the nuclei of infected cells by cross-reacting monoclonal antibodies with three serotypes of Marek's disease virus. Of these, a 135,000-molecular-weight polypeptide common to all three serotypes was found to bind to both double-stranded and single-stranded DNAs.
D000818:Animals; D000911:Antibodies, Monoclonal; D002467:Cell Nucleus / Q000378:metabolism; D003429:Cross Reactions; D004247:DNA / Q000378:metabolism; D004277:DNA, Single-Stranded / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000276:immunology* / Q000378:metabolism; D005455:Fluorescent Antibody Technique; D008381:Herpesvirus 2, Gallid / Q000145:classification / Q000276:immunology* / Q000378:metabolism; D012703:Serotyping
D000911:Antibodies, Monoclonal; D004277:DNA, Single-Stranded; D004268:DNA-Binding Proteins; D004247:DNA