title: Studies on purine turnover in the camel (Camelus dromedarius) and zebu (Bos indicus).
abstract: Significantly higher hypoxanthine over uric acid ratios were found in camel plasma and urine, with respect to those of zebu. Enzyme levels of purine catabolism were markedly lower in camel than in zebu liver. Oxidation of hypoxanthine appears to be the limiting step of purine metabolism in camel liver. Any hepatic hypoxanthine appears to be actively converted into IMP in camel liver, rather than oxidized to uric acid.
mesh_terms: D015720:5'-Nucleotidase; D000243:Adenosine Deaminase / Q000378:metabolism; D000818:Animals; D002162:Camelus / Q000378:metabolism*; D002417:Cattle / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D009708:Nucleotidases / Q000378:metabolism; D011683:Purine-Nucleoside Phosphorylase / Q000378:metabolism; D011687:Purines / Q000378:metabolism*; D013045:Species Specificity; D014510:Urease / Q000378:metabolism; D014969:Xanthine Oxidase / Q000378:metabolism
chemical_list: D011687:Purines; D014969:Xanthine Oxidase; D011683:Purine-Nucleoside Phosphorylase; D009708:Nucleotidases; D015720:5'-Nucleotidase; D014510:Urease; D000243:Adenosine Deaminase