title: Evidence for efferent projections from the brain to the retina of the Mongolian gerbil (Meriones unguiculatus). A horseradish peroxidase tracing study.
abstract: Mongolian gerbils were injected into the vitreous body of the left eye with either horseradish peroxidase or horseradish peroxidase coupled to wheat germ agglutinin. After survival times ranging from 6 to 48 hours, the animals were sacrificed and perfused with glutaraldehyde. Cryostat sections were cut through the brains and reacted for peroxidatic activity. Labelled perikarya were observed in the dorsal nucleus of the lateral geniculate body, the medial and lateral nuclei of the optic tract, the pretectal nuclei and the superior colliculus. These results indicate the presence of an efferent innervation of the retina from the brain via the optic nerve in the Mongolian gerbil.
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology*; D004525:Efferent Pathways / Q000502:physiology; D005260:Female; D005829:Geniculate Bodies / Q000502:physiology; D005849:Gerbillinae; D006735:Horseradish Peroxidase; D037102:Lectins; D008297:Male; D012160:Retina / Q000502:physiology*; D009435:Synaptic Transmission; D014795:Visual Pathways / Q000502:physiology; D014909:Wheat Germ Agglutinins
chemical_list: D037102:Lectins; D014909:Wheat Germ Agglutinins; D006735:Horseradish Peroxidase