title: The sequence of foot-and-mouth disease virus RNA to the 5' side of the poly(C) tract.
abstract: The nucleotide sequence of foot-and-mouth disease virus (FMDV) RNA to the 5' side of the poly(C) tract (S fragment) has been determined for representatives of the A and O serotypes of the virus. The two S fragments differ in length by five nucleotides (nt), with 367 nt for O1 compared with 362 nt for A10, due to a number of insertions/deletions. However, the two sequences show 86% homology. There are no conserved open reading frames (ORFs). Secondary structure predictions reveal a high degree of potential base-pairing, such that the entire S fragment sequence can be folded into a hairpin structure.
mesh_terms: D005537:Aphthovirus / Q000235:genetics*; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000032:analysis; D004279:DNA, Viral / Q000302:isolation & purification*; D009690:Nucleic Acid Conformation; D009693:Nucleic Acid Hybridization; D011066:Poly C / Q000302:isolation & purification; D012703:Serotyping
chemical_list: D004279:DNA, Viral; D011066:Poly C; D004247:DNA