title: Perineuritis and ulcerative colitis.
abstract: We describe the association of chronic polyneuropathy with ulcerative colitis. Electrophysiologic studies disclosed a severe neuropathy with both axonal and demyelinating features. The CSF protein content was 875 mg/dl. Sural nerve biopsy revealed perineuritis. Peripheral neuropathy with perineuritis may be an immunologically mediated extraintestinal manifestation of ulcerative colitis.
mesh_terms: D003093:Colitis, Ulcerative / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009186:Myelin Sheath / Q000473:pathology / Q000648:ultrastructure; D009431:Neural Conduction; D010523:Peripheral Nervous System Diseases / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D013497:Sural Nerve / Q000473:pathology / Q000648:ultrastructure