Immunocytochemical investigation of native matrix granules of the rat heart mitochondrion.
We have examined the ultrastructure and the protein content of native matrix granules (NMG) in rat heart mitochondria, by postembedding immunocytochemistry. Cytochrome c oxidase was found to be present in these granules. It is believed that these granules contain incomplete inner mitochondrial membrane fractions, which can be incorporated in the membrane after stimulation of the metabolism.
D000654:Amobarbital / Q000494:pharmacology; D000818:Animals; D003576:Electron Transport Complex IV / Q000276:immunology / Q000378:metabolism; D005260:Female; D005779:Immunodiffusion; D007425:Intracellular Membranes / Q000201:enzymology / Q000648:ultrastructure; D008854:Microscopy, Electron; D008929:Mitochondria, Heart / Q000201:enzymology / Q000648:ultrastructure*; D051381:Rats
D003576:Electron Transport Complex IV; D000654:Amobarbital