Further experience with Kaposi's sarcoma in Uganda.
Four Ugandan patients (1 women, 3 men) with generalized Kaposi's sarcoma (KS) were seen in the Uganda Cancer Institute between October 1983 and December 1984. They presented with generalized lymphadenopathy, plaques/nodules on the body, general swelling of the head, oral and visceral involvement and respiratory distress. Initial responses to adriamycin as a single or a combination chemotherapy of actinomycin D, vincristine, adriamycin and imidazole carboxamide appeared to be favourable but no sustained response was obtained. Serological tests for human T-lymphotropic virus (HTLV-II) antibodies were positive in all 4 cases.
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D017977:Deltaretrovirus / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D012514:Sarcoma, Kaposi / Q000453:epidemiology / Q000276:immunology / Q000473:pathology*; D014454:Uganda
D000914:Antibodies, Viral