Biliverdin as an electron transfer catalyst for superoxide ion in aqueous medium.
Stopped flow experiments gave evidence of the formation of a biliverdin-superoxide complex and/or a biliverdin radical anion by reaction of aqueous O2- with biliverdin. Such transient species are likely intermediates both in the bleaching of biliverdin, during exposure to the aerobic xanthine oxidase reaction, and in the reduction of ferricytochrome c under the same conditions.
D001663:Bilirubin / Q000031:analogs & derivatives*; D001664:Biliverdine / Q000378:metabolism*; D003574:Cytochrome c Group / Q000378:metabolism; D004579:Electron Transport; D005609:Free Radicals; D007700:Kinetics; D010084:Oxidation-Reduction; D010100:Oxygen / Q000378:metabolism; D013481:Superoxides / Q000378:metabolism*; D014969:Xanthine Oxidase / Q000378:metabolism
D003574:Cytochrome c Group; D005609:Free Radicals; D013481:Superoxides; D014969:Xanthine Oxidase; D001664:Biliverdine; D001663:Bilirubin; D010100:Oxygen