title: The DNA sequence recognized by the EcoDXX1 restriction endonuclease.
abstract: EcoDXX1 is a type-I restriction enzyme coded for by the plasmid pDXX1. Like other type-I restriction endonucleases, the enzyme catalyses the modification of susceptible DNA. We have determined the DNA sequence recognised by EcoDXX1 to be: 5'TCANNNNNNNATTC-3' 3'-AGTNNNNNNNTAAG-5' where N can be any nucleotide. This sequence has an overall structure very similar to previously determined type-I sequences.
mesh_terms: D010584:Bacteriophage phi X 174 / Q000235:genetics; D001483:Base Sequence; D001665:Binding Sites; D002384:Catalysis; D004262:DNA Restriction Enzymes / Q000378:metabolism*; D015280:DNA Restriction-Modification Enzymes; D004279:DNA, Viral; D008745:Methylation; D008780:Methyltransferases / Q000378:metabolism*
chemical_list: D015280:DNA Restriction-Modification Enzymes; D004279:DNA, Viral; D008780:Methyltransferases; D004262:DNA Restriction Enzymes; C046915:endodeoxyribonuclease EcoDXXI