IgG subclass of anti-HSV antibodies following neonatal HSV infections.
Ten survivors of neonatal HSV encephalitis had IgG1 and IgG3 antibodies to HSV 6 or more months after their infection. Six had IgG4 antibodies but only one had IgG2 antibodies. Titers of anti-HSV antibodies were similar following neonatal and later HSV infections. Antibody deficiency is thus not part of the selective deficiency of HSV-specific immunity following neonatal infection.
D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D002648:Child; D004660:Encephalitis / Q000276:immunology*; D006561:Herpes Simplex / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007231:Infant, Newborn; D018139:Simplexvirus / Q000276:immunology*; D013997:Time Factors
D000914:Antibodies, Viral; D007074:Immunoglobulin G