The pharmacology of agents used in the treatment of pulmonary mycoses.
The different antifungals currently used in pulmonary mycoses consist of polyene antibiotics, the antimetabolite 5-fluorocytosine, and azole derivatives. The pharmacologic profiles, mechanisms of action, pharmacokinetics, clinical indications for use, dosage recommendations, side effects, and drug interactions for these agents are presented.
D000666:Amphotericin B / Q000494:pharmacology; D000935:Antifungal Agents / Q000494:pharmacology* / Q000627:therapeutic use; D004347:Drug Interactions; D005437:Flucytosine / Q000494:pharmacology; D006801:Humans; D017964:Itraconazole; D007654:Ketoconazole / Q000031:analogs & derivatives / Q000494:pharmacology; D008172:Lung Diseases, Fungal / Q000188:drug therapy*; D008825:Miconazole / Q000494:pharmacology
D000935:Antifungal Agents; D017964:Itraconazole; D008825:Miconazole; D000666:Amphotericin B; D005437:Flucytosine; D007654:Ketoconazole