Dithiocarbamates in heavy metal poisoning: complexes of N,N-di(2-hidroxyethyl)dithiocarbamate with Zn(II), Cd(II), Hg(II), CH3Hg(II), and C6H5Hg(II).
The complexes M(DHDC)2, CH3Hg(DHDC), and C6H5Hg(DHDC) (M = Zn, Cd, Hg; DHDC = N,N-di(2-hydroxyethyl)dithiocarbamate) were prepared and investigated in solution and in the solid state by using 1H and 13C NMR, ir, and Raman spectroscopy. The dithiocarbamate group is anisobidentate and the complexes are associated in solution and the solid state via hydrogen bonding. The possible relation of these structural properties to the behavior of DHDC in the treatment of cadmium poisoning is discussed.
D002104:Cadmium; D055598:Chemical Phenomena; D002621:Chemistry; D004050:Ditiocarb / Q000031:analogs & derivatives; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008628:Mercury; D008670:Metals / Q000506:poisoning*; D008767:Methylmercury Compounds; D013859:Thiocarbamates; D015032:Zinc
D008670:Metals; D008767:Methylmercury Compounds; D013859:Thiocarbamates; D002104:Cadmium; C030957:methylmercury II; D004050:Ditiocarb; D008628:Mercury; C039353:dihydroxyethyldithiocarbamate; D015032:Zinc