Assignment of pancreatic ribonuclease gene to mouse chromosome 14.
A pancreatic ribonuclease cDNA was used as a probe for Southern blot hybridization of genomic DNA from recombinant inbred strains of mice. The results indicated that the gene coding for pancreatic ribonuclease (Rib-1) can be assigned to mouse chromosome 14. Analysis of the congenic strain B10.D2(57N)Sn confirmed this assignment and indicated that Rib-1 is closely linked to the genes encoding the T-cell receptor alpha subunit (Tcra) and nucleoside phosphorylase-2 (Np-2).
D000483:Alleles; D000818:Animals; D002874:Chromosome Mapping; D004262:DNA Restriction Enzymes; D005796:Genes; D007621:Karyotyping; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D012259:Ribonuclease, Pancreatic / Q000235:genetics*
D004262:DNA Restriction Enzymes; D012259:Ribonuclease, Pancreatic