[Bowenoid papulosis and its relation to Bowen's disease and atypical condyloma].
All the 5 sexual partners of male patients suffering from bowenoid papulosis and bearing the HPV 16 genome showed cervical lesions induced by HPV. 2 of them proved to be noncondylomatous infections, 3 cases were cervical condylomas, and 2 patients revealed severe dysplasia or carcinoma in situ (CIS). 3 out of 4 women suffering from multicentrical pigmented Bowen's disease of the vulva showed plain condylomas of the cervix, with severe dysplasia or CIS in 2 cases and slight dysplasia in one case. Thus bowenoid papulosis as well as multicentrical pigmented Bowen's disease of the vulva are high risk factors for cervical HPV infection and carcinoma, both for the patients themselves and their sexual partners. Atypical pigmented genital condylomas induced by HPV 6 also bear a risk for cervical HPV infection of the sexual partners. Malignant transformation, however, seems to depend on the type of the infecting virus (mainly HPV 16).
D001913:Bowen's Disease / Q000150:complications* / Q000473:pathology; D002278:Carcinoma in Situ / Q000150:complications / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000150:complications*; D002471:Cell Transformation, Neoplastic; D003218:Condylomata Acuminata / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D027383:Papillomaviridae / Q000145:classification; D012306:Risk; D012878:Skin Neoplasms / Q000150:complications* / Q000473:pathology; D014412:Tumor Virus Infections / Q000150:complications* / Q000382:microbiology / Q000635:transmission; D002578:Uterine Cervical Dysplasia / Q000150:complications / Q000473:pathology; D002583:Uterine Cervical Neoplasms / Q000150:complications* / Q000473:pathology
Bowenoide Papulose und ihr Zusammenhang mit Bowen'scher Krankheit und atypischen Kondylomen.