Genetic disorders of the anterior pituitary gland.
This survey deals with disorders caused by genetically disturbed function of the anterior pituitary gland. Genetic Dwarfism may be caused by isolated growth hormone deficiency (IGHD) or panpituitary diseases, such as congenital absence of the pituitary or familial panhypopituitarism. Genetic disturbances of isolated pituitary hormone secretion without dwarfism may occur as isolated gonadotropin deficiency (IGD), isolated luteinizing hormone deficiency ("fertile eunuch"), Kallmann syndrome (olfactogenital dysplasia), isolated thyrotropin deficiency (ITD) and isolated corticotropin deficiency (ICD). Pituitary dysfunction may also be associated with other genetic disease entities.
D000324:Adrenocorticotropic Hormone / Q000172:deficiency; D004392:Dwarfism / Q000235:genetics*; D005640:Follicle Stimulating Hormone / Q000172:deficiency; D005808:Genes, Recessive; D013006:Growth Hormone / Q000172:deficiency; D006801:Humans; D007986:Luteinizing Hormone / Q000172:deficiency; D010900:Pituitary Diseases / Q000235:genetics*; D010903:Pituitary Gland, Anterior / Q000002:abnormalities; D011627:Puberty; D013972:Thyrotropin / Q000172:deficiency; D014960:X Chromosome
D000324:Adrenocorticotropic Hormone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin; D013006:Growth Hormone