Progress in pediatric solid tumors.
Since 1980, impressive progress in the treatment of solid tumors has altered the practice of pediatric surgical oncology. Because these advances have been balanced by both liberal and conservative viewpoints, an accurate reassessment of traditional approaches has been possible. Noteworthy alterations in chemotherapy, radiation therapy, and surgical attitudes have improved survival rates and lessened the morbidity associated with malignant disease. Close cooperation among surgeons, pediatricians, and oncologists remains the common denominator in the successful treatment of pediatric solid tumors. This article presents examples of progress in the treatment of Hodgkin's disease, metastatic pulmonary disease, Wilms' tumor, and rhabdomyosarcoma and discusses the role of surgical intervention in conjunction with chemotherapy and radiation therapy.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002408:Catheters, Indwelling; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D006689:Hodgkin Disease / Q000473:pathology / Q000601:surgery; D006801:Humans; D007223:Infant; D007430:Intraoperative Care / Q000379:methods; D007680:Kidney Neoplasms / Q000601:surgery; D008175:Lung Neoplasms / Q000556:secondary / Q000601:surgery; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local; D009369:Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery*; D010372:Pediatrics / Q000379:methods*; D011379:Prognosis; D012208:Rhabdomyosarcoma / Q000556:secondary / Q000601:surgery; D013156:Splenectomy / Q000379:methods; D009396:Wilms Tumor / Q000601:surgery