[Formation of the left-handed helix during simultaneous treatment of poly[d(GC)] with bis-netropsin and Zn(II) ions].
It has been found that the effect of AT-specific ligand and Zn2+ on GC-alternating polymer brings about transfer of the latter into Z-conformation.
D006146:Guanidines / Q000494:pharmacology*; D066298:In Vitro Techniques; D009429:Netropsin / Q000031:analogs & derivatives / Q000494:pharmacology*; D009690:Nucleic Acid Conformation; D011089:Polydeoxyribonucleotides; D015032:Zinc / Q000494:pharmacology*
D006146:Guanidines; D011089:Polydeoxyribonucleotides; C019530:poly(dC-dG); D009429:Netropsin; C032161:bis-netropsin; D015032:Zinc
Obrazovanie levoĭ spirali pri odnovremennom deĭstvii na poli[d(GTs)] bis-netropsina i ionov Zn(II).