[Kaposi sarcoma in acquired immune deficiency syndrome (AIDS). II: Light and electron microscopic and immunohistochemical peculiarities including the cytoskeleton].
AIDS-related lymphoadenopathy is characterised by follicular hyperplasia with irregularities in the dendritic network, a loss of the follicular mantle zone and an enhanced influx of T-suppressor cells into the germinal centres. The histological features of AIDS-associated epidemic Kaposi's sarcoma are spindle-like tumour cells and a source vascularisation, which is of clinical relevance for the biopsy. Since immunohistochemical markers specific for blood vessel endothelium can not be detected within the tumour cells an origin from this cell type gets unlikely. An origin from lymphatic endothelium however can still be discussed.
D000163:Acquired Immunodeficiency Syndrome / Q000473:pathology*; D000914:Antibodies, Viral / Q000032:analysis; D003599:Cytoskeleton / Q000648:ultrastructure*; D004727:Endothelium / Q000648:ultrastructure; D005455:Fluorescent Antibody Technique; D006258:Head and Neck Neoplasms / Q000648:ultrastructure; D006801:Humans; D007181:Inclusion Bodies, Viral / Q000648:ultrastructure; D008198:Lymph Nodes / Q000473:pathology; D008214:Lymphocytes / Q000648:ultrastructure; D008854:Microscopy, Electron; D012192:Retroviridae Infections / Q000473:pathology*; D012514:Sarcoma, Kaposi / Q000648:ultrastructure*; D012878:Skin Neoplasms / Q000648:ultrastructure*
D000914:Antibodies, Viral
Kaposi-Sarkom bei erworbenem Immundefekt-Syndrom (AIDS). Teil II: Licht-, elektronenmikroskopische und immunhistochemische Besonderheiten einschliesslich Cytoskelett.