title: [Burkitt's lymphoma-Epstein-Barr virus association in western Algeria. Clinical, cytological and serological aspects apropos of 34 pediatric cases].
abstract: Burkitt's lymphoma (BL) and naso-pharyngeal carcinoma (NPC) are tumors generally believed to be associated with Epstein-Barr virus (EBV). Algerian population could be considered at high risk for BL-EBV association. In a series of 34 BL patients observed by us between 1982 and 1984 characteristics were: 70% of children were under 5 years age, abdominal location in 90% of cases (n = 30), 13% only isolated, massive tumor burden (70% stage III after Murphy, 30% stage IV after Murphy and Duque-Hammershaimb), EBV serology titers above or equal to 640 in 60% of cases (anti-EBNA and anti-VCA) and 50% (anti-EA) respectively, presence of EBNA antigen in tumor cells found in 63% of cases, no complete correlation between serology positivity and EBNA presence.
mesh_terms: D000293:Adolescent; D000462:Algeria; D000914:Antibodies, Viral / Q000276:immunology; D000956:Antigens, Viral / Q000032:analysis; D002051:Burkitt Lymphoma / Q000453:epidemiology* / Q000276:immunology / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D004854:Herpesvirus 4, Human / Q000276:immunology*; D006801:Humans; D008297:Male; D012306:Risk
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral
vernacular_title: Association lymphome de Burkitt-virus d'Epstein-Barr dans l'ouest Algérien. Aspects cliniques, cytologiques et sérologiques à propos de 34 observations pédiatriques.