Effect of chrysotile asbestos fibers on germ cells of mice.
An Indian form of chrysotile asbestos procured from a local asbestos factory (Hyderabad) was tested for its toxic effects on spermatocytes and sperm of mice. Swiss albino male mice were fed orally with chrysotile asbestos suspended in water. The concentration tested was 20 mg/kg/day. Chronic oral administration of chrysotile failed to induce chromosomal aberrations and abnormal sperms in mice.
D000818:Animals; D001194:Asbestos / Q000633:toxicity*; D017632:Asbestos, Serpentine; D002869:Chromosome Aberrations; D008297:Male; D051379:Mice; D013094:Spermatozoa / Q000187:drug effects* / Q000648:ultrastructure
D017632:Asbestos, Serpentine; D001194:Asbestos