[Electroencephalographic analysis of inter-central relations in hypothalamo-reticulo-limbic brain structures during treatment with corticosteroids and neuropeptides].
Intercentral relations between hypothalamus, limbic system and reticular formation were studied in rabbits and rats under systemic and central action of DSIP, ACTH, corticosteroids and stress (aggressive-defensive behaviour). The results obtained demonstrate changes in the adrenal cortex resulting from stress-inducing adrenocortical hormone content. The increase was achieved by the rise in ACTH level resulting in corticosteroid level elevation (endogenous elevation-aggressive behaviour) and by corticosteroid injections (exogenous elevation). Correlation analysis of structural interrelations after ACTH and corticosteroid injections demonstrated an increased correlation between hypothalamo-reticular-limbic structures. DSIP was shown to have an opposite effect. Correlation analysis revealed the potentials for the formation of new functional interrelations between hypothalamo-reticular-limbic structure in the motivation of aggression (stress) and the levels of corticosterone and DSIP. DSIP action depends on the initial corticosteroid blood level and is more marked in stress-inducing concentrations.
D000324:Adrenocorticotropic Hormone / Q000097:blood / Q000494:pharmacology*; D000818:Animals; D003080:Cold Temperature; D003701:Delta Sleep-Inducing Peptide / Q000097:blood / Q000494:pharmacology*; D004569:Electroencephalography; D007031:Hypothalamus / Q000187:drug effects / Q000502:physiology*; D008297:Male; D011817:Rabbits; D012154:Reticular Formation / Q000187:drug effects / Q000502:physiology*; D013312:Stress, Physiological / Q000503:physiopathology*
D003701:Delta Sleep-Inducing Peptide; D000324:Adrenocorticotropic Hormone
Elektroéntsefalograficheskiĭ analiz mezhtsentral'nykh vzaimootnosheniĭ gipotalamoretikulolimbicheskikh struktur mozga pri deĭstvii kortikosteroidov i neĭropeptidov.