Benzodiazepine receptor binding is not altered in human epileptogenic cortical foci.
We measured benzodiazepine binding in cortical tissues from 13 patients with partial seizures. No differences in receptor density (Bmax) or affinity (Kd) were observed when epileptic foci were compared with nonspiking cortex.
D000293:Adolescent; D000328:Adult; D002540:Cerebral Cortex / Q000378:metabolism* / Q000473:pathology / Q000503:physiopathology; D002648:Child; D004594:Electrophysiology; D004833:Epilepsy, Temporal Lobe / Q000378:metabolism* / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D011963:Receptors, GABA-A / Q000378:metabolism*
D011963:Receptors, GABA-A