Cell multiplication of an ascites tumour in the presence of superoxide dismutase and catalase.
Superoxide dismutase and catalase were demonstrated to favour the multiplication of ascites tumour cells in vitro. It is proposed that these enzymes neutralize the O2-. and H2O2 that may accumulate in the neoplastic cell and that cell damage occurs because the cellular levels of both enzymes are low.
D000818:Animals; D002374:Catalase / Q000378:metabolism; D002453:Cell Cycle; D004273:DNA, Neoplasm / Q000096:biosynthesis; D006861:Hydrogen Peroxide / Q000378:metabolism; D008325:Mammary Neoplasms, Experimental / Q000473:pathology*; D051379:Mice; D013482:Superoxide Dismutase / Q000378:metabolism; D013481:Superoxides / Q000378:metabolism
D004273:DNA, Neoplasm; D013481:Superoxides; D006861:Hydrogen Peroxide; D002374:Catalase; D013482:Superoxide Dismutase