[Formation of a streptothricin-group antibiotic by a Streptomyces glaucus 1136 culture].
In screening of new antibiotics a streptomycete (strain 1136) was isolated from a soil sample of Armenia. It showed no antagonistic properties in streek cultures on agarized media. When grown under submerged conditions strain 1136 produced an antibiotic active against grampositive and gramnegative bacteria. By its cultural and morphological properties strain 1136 was classified as Streptomyces glaucus Agre et Preobrazhenskaya, 1983. Microbiological and chemical investigation of the antibiotic produced by strain provided its identification at the early stages of the investigation as an antibiotic of the streptothricin group. Up to now no organisms producing streptothricin antibiotics were detected among streptomycetes of the Azureus section including strain 1136.
D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D000898:Antibiosis; D001136:Armenia; D012988:Soil Microbiology; D013171:Spores, Bacterial / Q000648:ultrastructure; D013302:Streptomyces / Q000145:classification / Q000166:cytology / Q000378:metabolism*; D013309:Streptothricins / Q000032:analysis / Q000096:biosynthesis* / Q000302:isolation & purification
D000900:Anti-Bacterial Agents; D013309:Streptothricins
Obazovanie antibiotika iz gruppy streptotritsinov kul'turoĭ Streptomyces glaucus 1136.