Müllerian adenosarcoma with ovarian sex cord-like differentiation. A light- and electron-microscopic study.
A Müllerian adenosarcoma in which the sarcomatous element showed ovarian sex-cord like differentiation, occurred as a polypoid growth in the uterine cervix of a 53-year-old woman. The tumor was composed of an admixture of benign neoplastic glands and a sarcomatous stroma, the latter containing in addition to endometrial stromal sarcoma, nests of lipid-rich cells resembling ovarian sex-cord elements. This is the first report of such differentiation in Müllerian adenosarcoma. Origin from a focus of cervical endometriosis is postulated.
D002454:Cell Differentiation; D005260:Female; D005487:Foam Cells / Q000473:pathology; D006801:Humans; D007044:Hysterectomy; D008197:Lymph Node Excision; D008875:Middle Aged; D009095:Mullerian Ducts; D010053:Ovary / Q000473:pathology*; D011127:Polyps / Q000473:pathology; D014594:Uterine Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D009396:Wilms Tumor / Q000473:pathology* / Q000648:ultrastructure