title: An unusual complication of silver nitrate treatment of hemorrhagic cystitis: case report.
abstract: A patient with severe cyclophosphamide cystitis was treated with intravesical silver nitrate instillation to control bleeding. This resulted in apparent reflux and extravasation of the silver nitrate solution with secondary retroperitoneal inflammation. Subsequently, the patient required treatment for a small, fibrotic bladder with persistent reflux. The precautions and recommendations for treatment of such difficult patients are discussed.
mesh_terms: D002675:Child, Preschool; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000009:adverse effects; D003556:Cystitis / Q000188:drug therapy* / Q000209:etiology; D005119:Extravasation of Diagnostic and Therapeutic Materials; D005260:Female; D006470:Hemorrhage / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D009373:Neoplasms, Germ Cell and Embryonal / Q000628:therapy; D011878:Radiotherapy / Q000009:adverse effects; D012187:Retroperitoneal Space / Q000187:drug effects*; D012445:Sacrococcygeal Region; D012835:Silver Nitrate / Q000009:adverse effects* / Q000627:therapeutic use; D001745:Urinary Bladder Diseases / Q000188:drug therapy / Q000209:etiology; D014718:Vesico-Ureteral Reflux / Q000139:chemically induced*
chemical_list: D003520:Cyclophosphamide; D012835:Silver Nitrate