title: A U3 RNA pseudogene in mouse: sequence and organization in genomic DNA.
abstract: A mouse U3 RNA pseudogene has been identified; it corresponds to a U3B full length coding sequence with a 3'-oligo(A) tail, precisely flanked at both ends by a pair of 15 bp direct repeats. These structural features suggest that it has arisen through an RNA-mediated mechanism involving an insertion at staggered nicks in the genome. Sequence data indicate that this mouse specimen has been generated by a different event as compared to the recently described rat pseudogenes. It represents the first reported case, for a pseudogene of this class, to be present at more than one copy per genome.
mesh_terms: D000818:Animals; D001483:Base Sequence; D004247:DNA / Q000235:genetics*; D004251:DNA Transposable Elements; D004274:DNA, Recombinant / Q000378:metabolism; D005796:Genes; D008099:Liver / Q000378:metabolism; D051379:Mice; D009693:Nucleic Acid Hybridization; D010957:Plasmids; D012342:RNA, Small Nuclear / Q000235:genetics* / Q000302:isolation & purification; D012689:Sequence Homology, Nucleic Acid
chemical_list: D004251:DNA Transposable Elements; D004274:DNA, Recombinant; D012342:RNA, Small Nuclear; D004247:DNA