title: The glucagonoma syndrome in a Chinese man.
abstract: The glucagonoma syndrome is a rare clinical condition. In this syndrome there is a pancreatic islet cell tumour which secretes glucagon, associated with a distinctive skin eruption--migratory necrolytic erythema. We describe a 79 year old Chinese man who presented with the typical skin features of this condition and on investigation had a pancreatic islet cell tumour. Serum glucagon levels were markedly elevated. He had a partial pancreatectomy and the skin rash improved dramatically. However he had liver metastases and responded poorly to streptozotocin. The skin features recurred and the patient died 9 months after diagnosis. As far as we are aware, this is the first report of a Glucagonoma syndrome in a Chinese.
mesh_terms: D007516:Adenoma, Islet Cell / Q000150:complications; D000368:Aged; D002681:China / Q000208:ethnology; D003131:Combined Modality Therapy; D004890:Erythema / Q000209:etiology; D005935:Glucagonoma / Q000150:complications / Q000188:drug therapy / Q000556:secondary / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary; D008297:Male; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000150:complications / Q000601:surgery; D012846:Singapore; D013577:Syndrome