Evidence of C-cell destruction in the thyroid gland of mice exposed to high 131I doses.
The parafollicular cells of the thyroid gland were visualized by means of the Sevier-Munger silver technique in normal mice and in mice receiving 131I in amounts sufficient to completely destroy the thyroid tissue. The destruction of the C-cells was observed in all 131I injected mice, and no histologic signs of recovery were seen during a period of 40 days following the treatment.
D000818:Animals; D007457:Iodine Radioisotopes; D051379:Mice; D008810:Mice, Inbred C57BL; D011833:Radiation Injuries, Experimental / Q000473:pathology*; D013961:Thyroid Gland / Q000528:radiation effects*
D007457:Iodine Radioisotopes