title: [Irradiation of grades III and IV astrocytomas with new types of radiation].
abstract: Until 1983, more than 300 astrocytomas of degree III and IV have been irradiated all over the world with new types of radiation such as neutrons, protons, alpha particles, heavy ions, and pions. Up to now a therapeutic progress could not be achieved. Radiobiologic experimentations suggest that the dense ionisation is unfavorable in the irradiation of malignant cerebral tumors. The clinical radiotherapy research with protons should therefore be intensified and hyperfractionation should be critically reviewed.
mesh_terms: D000512:Alpha Particles; D000818:Animals; D001932:Brain Neoplasms / Q000532:radiotherapy*; D005214:Fast Neutrons / Q000627:therapeutic use; D005909:Glioblastoma / Q000532:radiotherapy*; D006801:Humans; D007477:Ions; D008651:Mesons; D009374:Neoplasms, Experimental / Q000532:radiotherapy; D011522:Protons; D012062:Relative Biological Effectiveness
chemical_list: D007477:Ions; D011522:Protons
vernacular_title: Bestrahlung von Astrozytomen Grad III und IV mit neuen Strahlenarten.