[Cyclic AMP level in T- and B lymphocytes in patients with rheumatoid arthritis and systemic lupus erythematosus].
The content of cAMP in blood T and B lymphocytes was measured in 30 patients with rheumatoid arthritis (RA), 10 patients with systemic lupus erythematosus (SLE) and 28 donors. A statistically significant increase in the cAMP content in T lymphocytes of RA and SLE patients was established. On the contrary, in B lymphocytes of blood of RA patients and of SLE patients, in particular, the cAMP content was below normal. In female patients with RA, the cAMP content in T lymphocytes was appreciably higher than in male patients.
D000328:Adult; D000367:Age Factors; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000378:metabolism*; D001402:B-Lymphocytes / Q000378:metabolism*; D000242:Cyclic AMP / Q000097:blood*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D013601:T-Lymphocytes / Q000378:metabolism*
D000242:Cyclic AMP
Uroven' TsAMP v T- i B-limfotsitakh krovi bol'nykh revmatoidnym artritom i sistemnoĭ krasnoĭ volchankoĭ.