Lymphocytic hypophysitis with isolated corticotropin deficiency.
In a 32-year-old woman, acquired, isolated corticotropin deficiency resulted from postpartum lymphocytic hypophysitis. The literature suggests that lymphocytic hypophysitis may cause acquired deficiencies of anterior, and possibly posterior, pituitary hormones. Immunologic evaluation of our patient failed to uncover anticorticotroph antibodies. Prompt recognition of this potentially fatal condition is important because of the availability of effective treatment.
D000324:Adrenocorticotropic Hormone / Q000172:deficiency*; D000328:Adult; D001327:Autoimmune Diseases / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000378:metabolism; D007249:Inflammation / Q000378:metabolism / Q000473:pathology; D008214:Lymphocytes / Q000276:immunology / Q000473:pathology; D010900:Pituitary Diseases / Q000378:metabolism* / Q000473:pathology; D010903:Pituitary Gland, Anterior / Q000276:immunology / Q000473:pathology; D011247:Pregnancy; D011644:Puerperal Disorders / Q000378:metabolism / Q000473:pathology
D000324:Adrenocorticotropic Hormone