Effect of cytomegalovirus antigen on skin allograft survival in rabbits.
In experiments on rabbits it was found that the subcutaneous injection of cytomegalovirus (CMV) antigen into the draining lymphatic area of the skin allograft caused a decrease in graft survival. The difference of experimental versus control grafts was statistically significant. The finding supports some clinical data regarding the increased incidence of rejection episodes during CMV infection.
D000818:Animals; D000956:Antigens, Viral / Q000008:administration & dosage*; D003587:Cytomegalovirus / Q000276:immunology*; D003586:Cytomegalovirus Infections / Q000276:immunology; D005260:Female; D006085:Graft Survival; D008297:Male; D011817:Rabbits; D016038:Skin Transplantation; D014184:Transplantation, Homologous
D000956:Antigens, Viral