Cytogenetics of a renal adenocarcinoma in a 2-year-old child.
Chromosomal abnormalities in a 2.4-year-old boy with renal adenocarcinoma (Grawitz tumor) are described. Renal adenocarcinoma is extremely rare in childhood, compared with nephroblastoma (Wilms' tumor). In all tumor cells the same 46,XY,t(X;1) (p11.2;q21.2) karyotype was found. This karyotype is compared with the cytogenetic descriptions of renal adenocarcinoma in adults.
D002292:Carcinoma, Renal Cell / Q000235:genetics* / Q000473:pathology; D002675:Child, Preschool; D002871:Chromosome Banding; D002900:Chromosomes, Human, 1-3; D006801:Humans; D007621:Karyotyping; D007680:Kidney Neoplasms / Q000235:genetics* / Q000473:pathology; D008297:Male; D014178:Translocation, Genetic; D009396:Wilms Tumor / Q000235:genetics; D014960:X Chromosome