Effects of ACTH1-24 on male rat behavior in an exploratory, copulatory and socio-sexual approach test.
The effect of intraventricular application of ACTH1-24 on exploratory behavior, excessive grooming, and socio-sexual behavior in male rats was studied. It appeared that ACTH1-24 (1 microgram/animal) affects both excessive grooming and exploration. Sexual performance was delayed, as expressed in latency time to ejaculation, probably because of prolonged grooming behavior. The behavioral effects of ACTH are explained in terms of enhanced attention to external stimuli.
D000324:Adrenocorticotropic Hormone / Q000031:analogs & derivatives*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D003366:Cosyntropin / Q000494:pharmacology*; D004542:Ejaculation / Q000187:drug effects; D005106:Exploratory Behavior / Q000187:drug effects; D006120:Grooming / Q000187:drug effects; D007276:Injections, Intraventricular; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D011930:Reaction Time / Q000187:drug effects; D012726:Sexual Behavior, Animal / Q000187:drug effects; D012919:Social Behavior
D003366:Cosyntropin; D000324:Adrenocorticotropic Hormone