[Electron-microscopic study of monophasic spindle-cell synovial sarcomas].
Ultrastructural analysis of 9 monophasic spindle-cell synovial sarcomas revealed both undifferentiated tumour cells and histiocyte-like and fibroblast-like elements. Specialized contacts between tumour cells are found in 8 tumours, formation of the cavities of varying size (including vessel-like structure in 2 cases) in 7 tumours. Other findings included a discontinuous external lamina in 4 tumours; filopodium-like cell protrusions in 5, and spindle-shaped collagen bundles with long striation in 2 cases. The observation of cell contacts and cavities is of a diagnostic importance for monophasic synovial sarcoma. The differential diagnosis of these sarcomas and other spindle-cell tumours is discussed. Ultrastructural findings are interpreted as evidence of the monophasic spindle-cell synovial sarcoma origin from mesenchymal stem cells.
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005528:Foot; D006258:Head and Neck Neoplasms / Q000648:ultrastructure; D006801:Humans; D007717:Knee; D007866:Leg; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D013584:Sarcoma, Synovial / Q000648:ultrastructure*
Elektronno-mikroskopicheskoe issledovanie monofaznykh veretenokletochnykh sinovial'nykh sarkom.