[Inhibition of virus multiplication by immunoactive peptides].
In the present study we show that peritoneal macrophages obtained from the mice treated with the immunoactive peptides inhibit the multiplication of Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2), but not that of vesicular stomatitis virus (VSV), and that the intraperitoneal administration of the peptides suppresses the infection with HSV-1 in mice.
D000276:Adjuvants, Immunologic; D000818:Animals; D004261:DNA Replication; D005260:Female; D008264:Macrophages / Q000187:drug effects / Q000276:immunology*; D051379:Mice; D008813:Mice, Inbred ICR; D009842:Oligopeptides / Q000494:pharmacology*; D018139:Simplexvirus / Q000235:genetics*; D013329:Structure-Activity Relationship; D014721:Vesicular stomatitis Indiana virus / Q000235:genetics*; D014779:Virus Replication
D000276:Adjuvants, Immunologic; D009842:Oligopeptides; C047918:FR 48217; C039537:heptanoyl-gamma-D-glutamyl-L-meso-diaminopimelyl-D-alanine
Inhibition de la multiplication des virus par des peptides immunoactifs.