Mast cells in regional lymph nodes responding to syngeneic and xenogeneic tumour MSVC and HeLa cell lines in BALB/c mice.
In response to primary and secondary stimulation by xenogeneic HeLa carcinoma cells or by syngeneic sarcoma MSVC cells the regional lymph nodes of BALB/c mice are enlarged, however, their absolute mast cells content does not increase and in relative terms a decrease of mast cells concentration is observed. These results are in accordance with our earlier observations that during antigeneic and T-cell mitogen stimulation the lymphatic mast cells population does not increase but is rather reduced. This may indicate the engagement of these cells in delayed-type hypersensitivity.
D000818:Animals; D005260:Female; D006367:HeLa Cells / Q000637:transplantation*; D006801:Humans; D007116:Immunization, Passive; D007117:Immunization, Secondary; D008198:Lymph Nodes / Q000166:cytology* / Q000473:pathology; D008297:Male; D008407:Mast Cells / Q000502:physiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D009368:Neoplasm Transplantation; D009053:Sarcoma Viruses, Murine; D012513:Sarcoma, Experimental / Q000473:pathology; D014183:Transplantation, Heterologous; D014185:Transplantation, Isogeneic