The role of radiation therapy in the treatment of sarcoma of soft tissue.
The data presented indicate that the combination of function-preserving surgery and radiation therapy is of value in the treatment of soft tissue sarcomas of the extremity. Local control is obtained in approximately 85% of patients and with survival results comparable to those obtained in patients treated with radical surgery. The one randomized series of patients treated with conservative resection and radiation compared to amputation has shown no difference in overall survival. These local control results have been obtained while maintaining good functional results. Combined local resection and radiation is an appropriate treatment option in a large proportion of patients with soft tissue sarcomas.
D005354:Fibrosarcoma / Q000532:radiotherapy / Q000601:surgery; D018219:Histiocytoma, Benign Fibrous / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D007103:Immobilization; D007890:Leiomyosarcoma / Q000532:radiotherapy / Q000601:surgery; D008080:Liposarcoma / Q000532:radiotherapy / Q000601:surgery; D009455:Neurofibroma / Q000532:radiotherapy / Q000601:surgery; D011182:Postoperative Care; D011300:Preoperative Care; D011829:Radiation Dosage; D012208:Rhabdomyosarcoma / Q000532:radiotherapy / Q000601:surgery; D012509:Sarcoma / Q000532:radiotherapy* / Q000601:surgery; D013584:Sarcoma, Synovial / Q000532:radiotherapy / Q000601:surgery