[Formulation of the composition of a polymyxin ointment using a mathematical experimental design].
Mathematical design of the experiment permitted detection of the action of independent factors of the component composition on antibacterial activity and rheological properties of polymyxin ointment. Optimal compositions of polymyxin ointment based on polyethylene oxide emulsion were scientifically grounded and recommended for further experimental investigation on animals.
D001884:Bordetella / Q000187:drug effects; D002626:Chemistry, Pharmaceutical; D004339:Drug Compounding / Q000379:methods; D004655:Emulsions; D008433:Mathematics; D009824:Ointments; D011113:Polymyxins / Q000494:pharmacology*; D012107:Research Design; D014783:Viscosity
D004655:Emulsions; D009824:Ointments; D011113:Polymyxins
Razrabotka sostava polimiksinovoĭ mazi s primeniem matematicheskogo planirovaniia éksperimenta.