title: Lysogenic conversion of staphylococcal lipase is caused by insertion of the bacteriophage L54a genome into the lipase structural gene.
abstract: Staphylococcus aureus PS54 manifests no lipase (geh) activity. This is due to the insertion of bacteriophage L54a DNA into the geh structural gene. The nucleotide sequence of this 2,968-base-pair DNA fragment was determined. Lipase deduced from the nucleotide sequence is a polypeptide of 690 amino acids which extends from nucleotide 706 to 2776.
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D002872:Chromosome Deletion; D004262:DNA Restriction Enzymes / Q000378:metabolism; D004269:DNA, Bacterial / Q000032:analysis; D004279:DNA, Viral / Q000032:analysis; D005796:Genes; D008049:Lipase / Q000235:genetics*; D008242:Lysogeny; D009154:Mutation; D013210:Staphylococcus / Q000201:enzymology*; D013204:Staphylococcus Phages / Q000235:genetics*
chemical_list: D004269:DNA, Bacterial; D004279:DNA, Viral; D008049:Lipase; D004262:DNA Restriction Enzymes