title: Structural particularities of parainfluenza type 1 (Sendai) virus progens obtained by cultivation in the presence of ceruloplasmin.
abstract: Sendai virus multiplication in the presence of ceruloplasmin resulted in the appearance of qualitatively modified progens. There was an increase in the proportion of incomplete virus particles and a decrease in hemagglutinin and neuraminidase activities, in virus infectivity and antigenicity (with the exception of subviral fractions with predominant hemagglutinating activity). Virus progens obtained in the presence of ceruloplasmin had a higher sensitivity to detergent treatment; virus ghosts formed by re-aggregation of envelope fragments could be observed in the electron microscope.
mesh_terms: D000818:Animals; D002570:Ceruloplasmin / Q000494:pharmacology*; D002642:Chick Embryo; D008854:Microscopy, Electron; D010222:Parainfluenza Virus 1, Human / Q000187:drug effects* / Q000502:physiology / Q000648:ultrastructure; D014771:Virion / Q000187:drug effects* / Q000502:physiology / Q000648:ultrastructure; D014776:Virus Cultivation; D014779:Virus Replication / Q000187:drug effects
chemical_list: D002570:Ceruloplasmin