Production and quality control of the Oka-strain live varicella vaccine.
The Smith Kline-RIT live attenuated Oka-strain varicella vaccine (Varilrix) is manufactured following the seed lot principle, with each vaccine lot derived from the same working seed. Production of the vaccine basically consists in the multiplication of the working seed under standardized, well-defined conditions guaranteeing consistency of the vaccine lots. Quality control tests, determining the vaccine's purity, safety, potency, and efficacy, are carried out at each defined stage of the production process.
D019433:Chickenpox Vaccine; D014645:Herpesvirus 3, Human / Q000276:immunology*; D011786:Quality Control; D013678:Technology, Pharmaceutical; D014613:Vaccines, Attenuated / Q000592:standards; D014765:Viral Vaccines / Q000592:standards
D019433:Chickenpox Vaccine; D014613:Vaccines, Attenuated; D014765:Viral Vaccines