A mechanism in the control of intracellular cAMP level: the activation of a calmodulin-sensitive phosphodiesterase by a rise of intracellular free calcium.
D000818:Animals; D002118:Calcium / Q000494:pharmacology* / Q000502:physiology; D002147:Calmodulin / Q000494:pharmacology*; D002217:Carbachol / Q000494:pharmacology; D000242:Cyclic AMP / Q000502:physiology*; D006152:Cyclic GMP / Q000494:pharmacology; D004285:Dogs; D004533:Egtazic Acid / Q000494:pharmacology; D004789:Enzyme Activation / Q000187:drug effects; D006801:Humans; D009638:Norepinephrine / Q000494:pharmacology; D010726:Phosphodiesterase Inhibitors / Q000494:pharmacology; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism* / Q000494:pharmacology; D051381:Rats; D013961:Thyroid Gland / Q000201:enzymology
D002147:Calmodulin; D010726:Phosphodiesterase Inhibitors; D004533:Egtazic Acid; D002217:Carbachol; D000242:Cyclic AMP; D010727:Phosphoric Diester Hydrolases; D006152:Cyclic GMP; D002118:Calcium; D009638:Norepinephrine