Acute Chlamydia trachomatis respiratory infection in childhood. Serologic evidence.
Serum samples from 184 infants and children whose blood was drawn during a clinic visit were tested for antibody to Chlamydia trachomatis, Epstein-Barr virus, and cytomegalovirus. Lifetime illness history was obtained from clinic records. Fifteen percent had anti-C trachomatis IgM antibody. Anti-C trachomatis IgM without IgG was significantly associated with upper respiratory tract syndromes within the 14 days prior to phlebotomy in 6- to 10-year-old patients. This association was not due to polyclonal activation from Epstein-Barr virus infection. A definitive study of chlamydial illness in children rather than infants appears to be indicated.
D000208:Acute Disease; D000293:Adolescent; D000907:Antibodies, Bacterial / Q000032:analysis; D000914:Antibodies, Viral / Q000032:analysis; D000956:Antigens, Viral / Q000276:immunology; D002213:Capsid / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D002690:Chlamydia Infections / Q000175:diagnosis* / Q000276:immunology; D002692:Chlamydia trachomatis / Q000276:immunology; D003587:Cytomegalovirus / Q000276:immunology; D005260:Female; D004854:Herpesvirus 4, Human / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012141:Respiratory Tract Infections / Q000175:diagnosis* / Q000276:immunology
D000907:Antibodies, Bacterial; D000914:Antibodies, Viral; D000956:Antigens, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M