title: The effect of dietary guar on serum cholesterol, intestinal transit, and fecal output in man.
abstract: In six healthy subjects serum cholesterol was unchanged during a 2-wk period of controlled diet (2750 kcal) followed by a 2-wk period of free diet but showed a 16% decrease (p less than 0.05) during a further 2-wk period of controlled diet to which guar (5.7 g bid) was added. Stool weight, frequency and whole gut transit time did not differ in the diet periods with and without guar. Of guar ingested 82-95% was metabolized in the gut. Mouth to cecum transit of a meal measured by the hydrogen breath test in the same subjects was unaffected by the addition of 5.7 g of guar.
mesh_terms: D000328:Adult; D002784:Cholesterol / Q000097:blood*; D003672:Defecation; D004043:Dietary Fiber / Q000378:metabolism / Q000494:pharmacology*; D005243:Feces; D005685:Galactans / Q000378:metabolism / Q000494:pharmacology*; D005769:Gastrointestinal Motility; D006801:Humans; D007408:Intestinal Absorption; D008297:Male; D008351:Mannans / Q000378:metabolism / Q000494:pharmacology*; D053149:Plant Gums
chemical_list: D004043:Dietary Fiber; D005685:Galactans; D008351:Mannans; D053149:Plant Gums; D002784:Cholesterol; C007894:guar gum