title: Hyperthyroidism caused by a toxic intrathoracic goiter with a normal-sized cervical thyroid gland.
abstract: The rare presentation of hyperthyroidism caused by an intrathoracic goiter with a normal-sized cervical thyroid gland is described. The toxic intrathoracic goiter demonstrated avid uptake of [131I] and [99mTc]pertechnetate, with comparatively faint isotopic accumulation seen in the cervical thyroid. A chest roentgenogram and radioisotope scan should be mandatory in cases of hyperthyroidism having no cervical thyroid enlargement to explore the possibility of a toxic intrathoracic goiter.
mesh_terms: D005260:Female; D006045:Goiter, Substernal / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D006980:Hyperthyroidism / Q000000981:diagnostic imaging / Q000209:etiology*; D007457:Iodine Radioisotopes; D008875:Middle Aged; D011877:Radionuclide Imaging; D013670:Sodium Pertechnetate Tc 99m
chemical_list: D007457:Iodine Radioisotopes; D013670:Sodium Pertechnetate Tc 99m