title: [Comparative cytophotometric and cytomorphometric studies of concave cells and atypical squamous epithelial cells of the cervix uteri].
abstract: Cytologic slides from 11 women with clinical, cytological and histological signs of a papillomavirus infection of the cervix uteri are investigated by cytophotometry and cytomorphometry. The mean values of DNA content, chromatin density, nuclear area and nuclear circumference of koilocytes were notably higher than for atypical or normal squamous cells. In those patients with concurrent cervical intraepithelial neoplasia the DNA content of koilocytes was inversely related to the degree of atypia. Squamous cells with HPV-induced lesions can be characterized by cytophotometry and cytomorphometry as a distinct cell population forming a continuum with the preneoplastic epithelium.
mesh_terms: D002467:Cell Nucleus / Q000032:analysis / Q000648:ultrastructure; D002584:Cervix Uteri / Q000473:pathology*; D003592:Cytophotometry; D004247:DNA / Q000032:analysis; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D027383:Papillomaviridae; D014412:Tumor Virus Infections / Q000150:complications / Q000473:pathology*; D002577:Uterine Cervical Diseases / Q000150:complications / Q000473:pathology*; D002583:Uterine Cervical Neoplasms / Q000150:complications / Q000473:pathology
chemical_list: D004247:DNA
vernacular_title: Vergleichende zytophotometrische und zytomorphometrische Untersuchungen an Koilozyten und atypischen Plattenepithelzellen der Cervix uteri.