The role of dopamine in salivation in the rat parotid gland.
The ability of dopamine to evoke secretion from the rat parotid gland has been investigated. The actions of dopamine were investigated alone and during carbachol mediated secretion. Dopamine increased flow rate and protein secretion in both experimental models. The increase in protein secretion is mediated via beta 1-adrenoceptors whereas the increase in flow rate may be due to activation of specific dopamine receptor.
D000818:Animals; D002217:Carbachol / Q000494:pharmacology; D004298:Dopamine / Q000494:pharmacology*; D008297:Male; D010306:Parotid Gland / Q000187:drug effects* / Q000378:metabolism; D011506:Proteins / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D011943:Receptors, Adrenergic, beta / Q000187:drug effects / Q000502:physiology; D011954:Receptors, Dopamine / Q000187:drug effects / Q000502:physiology; D012472:Salivation / Q000187:drug effects*; D013565:Sympatholytics / Q000494:pharmacology
D011506:Proteins; D011943:Receptors, Adrenergic, beta; D011954:Receptors, Dopamine; D013565:Sympatholytics; D002217:Carbachol; D004298:Dopamine