A rapid microneutralization assay for cytomegalovirus.
A rapid, simple and reproducible microneutralization test for human cytomegalovirus is described. The results can be read in 1-2 days and the neutralization titer detected in human and guinea pig sera and in monoclonal antibody-containing supernatants is consistent with that derived by the plaque-reduction neutralization test.
D000818:Animals; D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral / Q000032:analysis*; D002460:Cell Line; D003587:Cytomegalovirus / Q000276:immunology*; D003588:Cytopathogenic Effect, Viral; D006168:Guinea Pigs; D006801:Humans; D009500:Neutralization Tests
D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral