title: Classification system for human T-lymphotropic virus type III/lymphadenopathy-associated virus infections. Centers for Disease Control, U.S. Department of Health and Human Services.
abstract: Infection with the human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) [now human immunodeficiency virus] can manifest as a spectrum of conditions ranging from severe immunodeficiency to asymptomatic infection. Because of the rapid growth of knowledge about this virus, there is a need for a system to classify patients with the various manifestations of infection. The presented system comprises four mutually exclusive groups: I, acute infection; II, asymptomatic infection, III, persistent generalized lymphadenopathy; and IV, other HTLV-III/LAV disease (with five subgroups, A to E, and two subcategories, C-1 and C-2). The classification should be useful in disease reporting and surveillance, epidemiologic studies, prevention and control activities, and public health policy and planning.
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000145:classification*; D000208:Acute Disease; D017977:Deltaretrovirus; D006801:Humans; D007239:Infections / Q000209:etiology; D008206:Lymphatic Diseases / Q000209:etiology; D009369:Neoplasms / Q000209:etiology; D009422:Nervous System Diseases / Q000209:etiology; D012192:Retroviridae Infections / Q000145:classification*