[Inhibition of Plasmodium berghei in rats infested with Strongyloides ratti or Trichinella spiralis; role of high blood corticosterone in reaction to the development of helminths].
The plasma corticosterone induced in the rat by the development of Strongyloides ratti or Trichinella spiralis reaches a sufficient level of intensity to determine reticulocytopenia. The latter is linked chronologically to the inhibition of parasitemia in Plasmodium berghei, which occurs when this protozoa develops at the same time as the Nematodes, and seems to be the causal factor. This hypothesis may be verified by replacing the helminths with the corticotropic action of A.C.T.H. which causes a decrease in the number of reticulocytes.
D000324:Adrenocorticotropic Hormone / Q000627:therapeutic use; D000818:Animals; D003345:Corticosterone / Q000097:blood*; D004906:Erythrocyte Count; D008288:Malaria / Q000469:parasitology*; D008297:Male; D010962:Plasmodium berghei / Q000254:growth & development*; D051381:Rats; D011919:Rats, Inbred Strains; D012156:Reticulocytes; D013322:Strongyloidiasis / Q000097:blood* / Q000469:parasitology; D013997:Time Factors; D014235:Trichinellosis / Q000097:blood* / Q000469:parasitology
D000324:Adrenocorticotropic Hormone; D003345:Corticosterone
Inhibition de Plasmodium berghei chez des rats infestes par Strongyloides ratti ou par Trichinella spiralis; rôle de l'hypercorticostéronémie réactionnelle à l'évolution des helminthes.