RNase H is not involved in the induction of stable DNA replication in Escherichia coli.
rnh mutations of Escherichia coli inactivating RNase H activity allow the initiation of rounds of DNA replication in the absence of protein synthesis (stable DNA replication). However, levels of RNase H did not change during or after the induction of stable DNA replication in rnh+ strains by incubation with nalidixic acid or UV irradiation.
D004261:DNA Replication / Q000528:radiation effects; D004722:Endoribonucleases / Q000037:antagonists & inhibitors / Q000502:physiology*; D004926:Escherichia coli / Q000378:metabolism*; D009154:Mutation; D009268:Nalidixic Acid / Q000494:pharmacology; D016914:Ribonuclease H
D009268:Nalidixic Acid; D004722:Endoribonucleases; D016914:Ribonuclease H