title: [Treatment of juvenile rheumatoid arthritis].
abstract: Recently interest in pediatric rheumatology has increased. This review tries to summarize our knowledge about pharmacological mechanisms, as well as practical application and adverse of antirheumatic drugs. In addition, forms of treatment which sofar lack any scientific backing are mentioned and discussed. Various data about efficacy and side effects in children are poor or lacking, and current treatment in children is based on analogy conclusions derived from experiences with adult RA. The therapeutic concept presented in this article offers a good chance to improve the functional status of the rheumatic child. However, one should be aware that several controlled trials with antirheumatic drugs in children still have to be performed. Uncertainties have to be replaced by knowledge. This is true also for the surgical treatment mentioned.
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000324:Adrenocorticotropic Hormone / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000962:Antimalarials / Q000627:therapeutic use; D001171:Arthritis, Juvenile / Q000188:drug therapy*; D001241:Aspirin / Q000627:therapeutic use; D002648:Child; D003131:Combined Modality Therapy; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005938:Glucocorticoids / Q000627:therapeutic use; D006046:Gold / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D010396:Penicillamine / Q000627:therapeutic use
chemical_list: D000276:Adjuvants, Immunologic; D000893:Anti-Inflammatory Agents; D000962:Antimalarials; D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D006046:Gold; D000324:Adrenocorticotropic Hormone; D010396:Penicillamine; D001241:Aspirin
vernacular_title: Behandlung der juvenilen rheumatoiden Arthritis.