[Invasive aspergillar pneumopathy during the treatment of microcellular bronchial cancer. Efficacy of early antifungal treatment].
The invasive aspergillus pneumonias have been described particularly in chemotherapy for patients with haematological disorders. In respiratory disorders such cases are exceptional. The authors report a case of invasive aspergillus pneumonia, occurring during treatment of a small cell cancer; the rapid commencement of anti-fungal treatment by Amphotericin "B" and Flucytosine enabled an apparent cure of the tumour by radiotherapy and chemotherapy. The authors stress the difficulty of definitive diagnostic criteria at the beginning of the disorder and also the need to start anti-fungal treatment as soon as possible.
D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001228:Aspergillosis / Q000188:drug therapy / Q000209:etiology*; D001232:Aspergillus fumigatus / Q000302:isolation & purification; D018288:Carcinoma, Small Cell / Q000150:complications / Q000628:therapy*; D004359:Drug Therapy, Combination; D005437:Flucytosine / Q000627:therapeutic use; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008172:Lung Diseases, Fungal / Q000188:drug therapy / Q000209:etiology*; D008175:Lung Neoplasms / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D011867:Radioisotope Teletherapy; D013183:Sputum / Q000382:microbiology
D000935:Antifungal Agents; D000666:Amphotericin B; D005437:Flucytosine
Pneumopathie aspergillaire invasive au cours du traitement d'un cancer bronchique microcellulaire. Efficacité du traitement antifungique précoce.