The effect of stress on proton relaxation times (T1 and T2) of rat liver.
T1 of the liver has been shown to lengthen after sham operation or partial hepatectomy, reaching a maximum about 24 hours after surgery. Surgical stress, which includes tissue injury and repair, has been suggested as the source of the change. We subjected rats to three types of stress that do not include tissue damage and repair to determine the role of stress alone in the length of T1 of the liver. Prolonged swimming, ACTH injection, or fasting did not affect T1 times. Tissue damage and/or repair appear to have a major role in determining T1 in the liver.
D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000818:Animals; D005215:Fasting; D008099:Liver / Q000473:pathology* / Q000502:physiology; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D005082:Physical Exertion; D051381:Rats; D011919:Rats, Inbred Strains; D013057:Spectrum Analysis; D013312:Stress, Physiological / Q000175:diagnosis*; D013550:Swimming; D013997:Time Factors
D000324:Adrenocorticotropic Hormone