title: [Signet-ring-cell lymphoma. Light and electron microscopic study of gastric involvement].
abstract: The authors report on a malignant Non-Hodgkin lymphoma of the stomach of a 73-year-old male. Histologically, it was revealed to be a follicularly growing, obviously secondary centroblastic lymphoma. Crystalline cytoplasmic inclusions in numerous centrocytes have led to displacement of the nucleus to the cell margin and thus to the picture of a signet-ring-cell lymphoma. Electronmicroscopically, there were found big crystalline electron-dense deposits in the rough endoplasmic reticulum. The finding was compared with literature data, and the histological differential diagnosis is discussed.
mesh_terms: D000368:Aged; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D008223:Lymphoma / Q000473:pathology* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D013274:Stomach Neoplasms / Q000473:pathology* / Q000648:ultrastructure
vernacular_title: Das Siegelringzellymphom Eine licht- und elektronenmikroskopische Studie bei Befall des Magens.