title: [The effect of short-term isolation of vaccinated chicks on the incidence of Marek's disease].
abstract: In chickens immunized by normal and tenfold doses of MARVAK vaccine (100 and 1,000 PFU) we investigated protective effects against the natural contact infection of chickens that were exposed to the infection immediately after vaccination, or at the intervals of 48 and 72 hours, and 7 and 14 days. Studying the elimination of Marek's disease virus by feather follicles, the health condition of chickens, tumor frequency and mortality rate we demonstrated that neither of these doses could protect the chickens from the disease if they were exposed to contact infection just after vaccination. An expressive protective effect was observed in chickens isolated for 7-14 days and there was not recorded any difference in the protection against the disease after the doses of 100 and 1,000 PFU. The main and feasible measure against MD is to prevent an early infection of newborn chickens by improving the zoohygienic conditions.
mesh_terms: D000818:Animals; D002645:Chickens; D008381:Herpesvirus 2, Gallid / Q000276:immunology; D007109:Immunity; D008380:Marek Disease / Q000276:immunology / Q000517:prevention & control*; D013997:Time Factors; D014611:Vaccination / Q000662:veterinary*; D014765:Viral Vaccines
chemical_list: D014765:Viral Vaccines
vernacular_title: Vliv krátkodobé izolace vakcinovaných kurat na výskyt Markovy choroby.