Long-term survival with tumor regression in androgen-induced liver tumors.
Two patients with androgen-induced liver tumors, one of whom had been partially treated by a liver resection, are reported. Hepatocellular carcinoma was diagnosed on histologic grounds. The patients had been receiving androgen therapy for primary diagnoses of either hypopituitarism or paroxysmal nocturnal hemoglobinuria. After androgen withdrawal, both are alive and well with no evidence of residual tumor 10 and 14 years after diagnosis, respectively.
D000328:Adult; D000728:Androgens / Q000009:adverse effects*; D006528:Carcinoma, Hepatocellular / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008777:Methyltestosterone / Q000009:adverse effects; D009365:Neoplasm Regression, Spontaneous; D010110:Oxymetholone / Q000009:adverse effects; D011877:Radionuclide Imaging
D000728:Androgens; D010110:Oxymetholone; D008777:Methyltestosterone