Foot-and-mouth disease virus-induced RNA polymerase is associated with Golgi apparatus.
Electrophoretic analysis of the Golgi apparatus isolated by differential centrifugation from radiolabeled cells infected with foot-and-mouth disease virus showed about 10 protein bands. The virus-induced RNA polymerase was identified by immunoprecipitation and electron microscope staining procedures. Pulse-chase experiments indicated that the polymerase passed through the Golgi apparatus in less than 1 h.
D000818:Animals; D005537:Aphthovirus / Q000201:enzymology* / Q000254:growth & development; D002460:Cell Line; D006224:Cricetinae; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism*; D006056:Golgi Apparatus / Q000201:enzymology*; D007425:Intracellular Membranes / Q000378:metabolism; D046911:Macromolecular Substances; D009024:Morphogenesis; D011499:Protein Processing, Post-Translational; D013997:Time Factors
D046911:Macromolecular Substances; D012321:DNA-Directed RNA Polymerases