Cross-correlation analysis of thalamic neurons and EMG activity in parkinsonian tremor.
Bursting activity in cells cross-correlated with electromyographic (EMG) activity during parkinsonian tremor. Statistically significant evidence of cross-correlation was found for 49% of cells located at the lesion target for relief of tremor. Statistically significant correlation was found for 90% of cells having tremor frequency power greater than twice 'average power' at nontremor frequencies. This population of cells may be involved in the generation of parkinsonian tremor.
D004576:Electromyography; D005071:Evoked Potentials; D006801:Humans; D009132:Muscles / Q000294:innervation; D009474:Neurons / Q000502:physiology; D010300:Parkinson Disease / Q000503:physiopathology*; D009435:Synaptic Transmission; D013787:Thalamic Nuclei / Q000503:physiopathology*; D014202:Tremor / Q000503:physiopathology