title: [Regulation of cAMP cascade by yeast RAS genes].
abstract: In the yeast, Saccharomyces cerevisiae, cell proliferation is regulated by cAMP through cAMP-dependent protein kinase. Cyclic AMP-dependent phosphorylation is involved in the G1 phase of the cell cycle, conjugation, and the post-meiotic stage of sporulation, but inhibition of cAMP-dependent protein phosphorylation is required in order to induce meiotic division. The yeast RAS gene, which is homologous to the H-ras gene, is one of several genes which are related to cAMP-cascade, and its product seems to be a regulatory protein of adenylate cyclase.
mesh_terms: D000262:Adenylyl Cyclases / Q000378:metabolism; D002453:Cell Cycle; D000242:Cyclic AMP / Q000502:physiology*; D009154:Mutation; D009857:Oncogenes; D010766:Phosphorylation; D011494:Protein Kinases / Q000502:physiology; D012441:Saccharomyces cerevisiae / Q000235:genetics*
chemical_list: D000242:Cyclic AMP; D011494:Protein Kinases; D000262:Adenylyl Cyclases