[LAV type II: a second retrovirus associated with AIDS in West Africa].
A second retrovirus, named LAV-II, has been isolated from two West-African patients with AIDS. By its genomic sequences and its proteins, this virus is different from the LAV-I/HTLV-III, isolated from U.S.A., Europe and Central Africa. It differs also from STLV-III, isolated from Rhesus Macaques with AIDS, but displays an antigenic relationship with the latter virus, at the level of its external envelope protein. The tropism of LAV-II for T4 lymphocytes and the induction of cytopathic effect in infected cells are similar to those of LAV-I.
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology / Q000382:microbiology*; D000328:Adult; D000354:Africa, Western; D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D017977:Deltaretrovirus / Q000145:classification / Q000276:immunology / Q000302:isolation & purification*; D015023:Democratic Republic of the Congo; D015488:HIV Antigens; D006801:Humans; D008253:Macaca mulatta; D008297:Male; D013601:T-Lymphocytes / Q000276:immunology; D009626:Terminology as Topic
D000956:Antigens, Viral; D015488:HIV Antigens
LAV type II: un second rétrovirus associé au SID A en Afrique de l'Ouest.