Comparison of benzodiazepine receptors in cerebellum and inferior colliculus.
Reversible and irreversible binding of [3H]flunitrazepam was investigated in membranes from cerebellum and inferior colliculus of young and adult rats. Results indicate that in adult animals predominantly BZ1 receptors are enriched in both brain regions. In the brains of newborn animals, however, additional benzodiazepine receptor subtypes seem to exist in cerebellum as well as in inferior colliculus.
D000375:Aging; D000818:Animals; D000831:Animals, Newborn / Q000378:metabolism; D002243:Carbolines / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism; D002531:Cerebellum / Q000378:metabolism*; D002998:Clonazepam / Q000378:metabolism; D003975:Diazepam / Q000378:metabolism; D005445:Flunitrazepam / Q000378:metabolism; D007245:Inferior Colliculi / Q000378:metabolism*; D011724:Pyridazines / Q000378:metabolism; D051381:Rats; D011963:Receptors, GABA-A / Q000378:metabolism*
D002243:Carbolines; D011724:Pyridazines; D011963:Receptors, GABA-A; D002998:Clonazepam; D005445:Flunitrazepam; C021604:CL 218872; C024915:beta-carboline-3-carboxylic acid ethyl ester; D003975:Diazepam