Antigenic and molecular properties of type 3 poliovirus responsible for an outbreak of poliomyelitis in a vaccinated population.
Virus isolated from an outbreak of poliomyelitis in Finland has been examined serologically and at the molecular level. The causative agent was an antigenically unusual strain of type 3 poliovirus, which was unrelated to the strains used to manufacture either live or killed poliovaccines. It is likely that the antigenic properties of the virus played a part in establishing a limited outbreak of poliomyelitis in a vaccinated population.
D000595:Amino Acid Sequence; D000956:Antigens, Viral / Q000235:genetics; D001483:Base Sequence; D005243:Feces / Q000382:microbiology; D005387:Finland; D006801:Humans; D009664:Norway; D009843:Oligoribonucleotides / Q000032:analysis; D011051:Poliomyelitis / Q000453:epidemiology* / Q000276:immunology; D017955:Poliovirus / Q000235:genetics / Q000276:immunology* / Q000302:isolation & purification; D012367:RNA, Viral / Q000302:isolation & purification; D006163:Ribonuclease T1; D013548:Sweden; D014611:Vaccination
D000956:Antigens, Viral; D009843:Oligoribonucleotides; D012367:RNA, Viral; D006163:Ribonuclease T1