Laetrile intoxication and hepatic necrosis: a possible association.
A 65-year-old woman with cirrhosis and hepatoma lapsed into deep coma, hypotension, and acidosis after ingestion of 3 gm of Laetrile, a cyanogenetic glucoside. After initial treatment, the patient regained consciousness, but massive hepatic damage led to her death. We suggested a possible relationship between Laetrile poisoning and massive hepatic necrosis.
D000368:Aged; D000678:Amygdalin / Q000506:poisoning*; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology*; D008103:Liver Cirrhosis / Q000188:drug therapy; D008113:Liver Neoplasms / Q000188:drug therapy; D009336:Necrosis
D000678:Amygdalin