[Shifts in the antioxidant activity in the membrane structures of virus-infected cells].
It is assumed that the process of virus infection of cells causes significant changes in the conditions of lipid peroxidation in membrane structures of such cells. Experiments with virus-infected HeLa cells demonstrated noticeable decrease in the capacity of membrane lipids for peroxidation induced by ultraviolet irradiation and iron monoxide ions. Similar changes were also observed in membranes of chick embryo liver cells infected with viruses. The established reduced capacity of lipids in membranes of virus-infected cells to induced peroxidation (interpreted as the increase of their antioxidant activity) is characteristic of whole membranes only, because the lipids extracted from infected and control cells showed no differences in their capacity to peroxidation in liposomal membranes when oxidation was induced by iron monoxide.
D000257:Adenoviridae Infections / Q000378:metabolism*; D000258:Adenovirus Infections, Human / Q000378:metabolism*; D000818:Animals; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D002478:Cells, Cultured; D002642:Chick Embryo; D006367:HeLa Cells / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D006801:Humans; D007251:Influenza, Human / Q000378:metabolism*; D007501:Iron / Q000494:pharmacology; D008054:Lipid Peroxides / Q000378:metabolism* / Q000528:radiation effects; D008099:Liver / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D008163:Luminescent Measurements; D008563:Membrane Lipids / Q000378:metabolism*; D010084:Oxidation-Reduction / Q000187:drug effects / Q000528:radiation effects; D014466:Ultraviolet Rays
D008054:Lipid Peroxides; D008563:Membrane Lipids; D007501:Iron
Sdvigi antioksidantnoĭ aktivnosti v membrannykh strukturakh kletok, zarazhennykh virusami.