[Localization of metronidazole in the organs of tumor-bearing animals using electron paramagnetic resonance].
The low-temperature ESR-spectroscopy was used to study the irradiated organs and blood of tumor-bearing animals before and after the administration of metronidazole. The ESR signals of metronidazole anion-radicals were registered in tissues of the animals injected with metronidazole: the intensity of these signals correspondent with the tissues preparation content.
D000818:Animals; D004578:Electron Spin Resonance Spectroscopy; D008795:Metronidazole / Q000378:metabolism*; D051379:Mice; D011838:Radiation-Sensitizing Agents / Q000378:metabolism*; D012511:Sarcoma 37 / Q000378:metabolism*; D012513:Sarcoma, Experimental / Q000378:metabolism*; D014018:Tissue Distribution
D011838:Radiation-Sensitizing Agents; D008795:Metronidazole
Izuchenie lokalizatsii metronidazola v organakh zhivotnykh-opukholenositeleĭ metodom élektronnogo paramagnitnogo rezonansa.