Mixed germ cell tumor of the ovary with pure choriocarcinoma metastasis.
A case report of a 30-month disease-free survival in a ten-year-old girl with ovarian mixed germ cell tumor consisting of dysgerminoma, choriocarcinoma, and immature teratoma with pure choriocarcinoma paraaortic lymph node metastasis is presented. To prevent resistant cell colonies, the noncross-resistant combination of vinblastine-Adriamycin and vinblastine-actinomycin D-cytoxan were added to the initial four courses of vinblastine-cisplatin-bleomycin. There are no previously reported survivals in ovarian mixed germ cell tumors with pure choriocarcinoma metastasis.
D002648:Child; D002822:Choriocarcinoma / Q000473:pathology / Q000556:secondary*; D003131:Combined Modality Therapy; D004407:Dysgerminoma / Q000473:pathology; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D009373:Neoplasms, Germ Cell and Embryonal / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D011247:Pregnancy; D013724:Teratoma / Q000473:pathology