title: Nonaspiration-needle smear preparations of pulmonary lesions. A comparison of cytology and histology.
abstract: Material for cytologic smears was obtained from pulmonary lesions in 146 patients at the Ohio State University between 1979 and 1984 using Rotex or Lee screw needles. Corresponding histologic specimens were available for comparison in 77 of these cases. Diagnoses of malignant neoplasms made by cytologic evaluation (55 cases) were confirmed by the corresponding histologic specimens in 93% of those cases. Possible explanations for the cytologic false-positive diagnoses of malignancy are presented. Correlations between the cytologic and histologic diagnoses of the morphologic type of tumor were 100% for adenocarcinoma, 75% for squamous-cell carcinoma and 20% for large-cell undifferentiated carcinoma. The correlation was 100% for small-cell carcinoma when the histology specimen represented the tumor. Nonneoplastic benign lesions diagnosed cytologically had corresponding benign histologic diagnoses in 94% of the cases. These results compare favorably with those reported for other fine needle aspiration studies of pulmonary lesions. The advantages of using Rotex needles as compared to fine needle aspiration are discussed.
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D001707:Biopsy, Needle / Q000295:instrumentation / Q000379:methods*; D002276:Carcinoid Tumor / Q000473:pathology; D002277:Carcinoma / Q000473:pathology; D018288:Carcinoma, Small Cell / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D002822:Choriocarcinoma / Q000473:pathology / Q000556:secondary; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000473:pathology*; D008175:Lung Neoplasms / Q000473:pathology* / Q000556:secondary; D008223:Lymphoma / Q000473:pathology; D009336:Necrosis; D011014:Pneumonia / Q000473:pathology; D011247:Pregnancy