title: [Surgical prevention in precancerous conditions and noninvasive cancers of the breast].
abstract: The biological significance of precancerous lesions and non-invasive carcinoma of the breast are compared, particularly proliferative mastopathy with cellular atypia (so-called mastopathy grade III), ductal papillomatosis, non-infiltrating intraductal carcinoma (IDC) and lobular in situ carcinoma (CLIS). While biological significance has been described for most tissue pathology choice of therapy is difficult because the clinical course following local excision is not readily assessed. For therapy of individual patients, their pathology, individual situation and risk factors are to be considered. In general a conservative, expectant treatment is recommended for all lesions following local excision. More radical surgery is recommended for IDC, although a number of factors precluding radical procedures may be discussed.
mesh_terms: D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D002277:Carcinoma / Q000601:surgery; D002278:Carcinoma in Situ / Q000601:surgery; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000601:surgery; D005260:Female; D005348:Fibrocystic Breast Disease / Q000601:surgery; D006801:Humans; D008408:Mastectomy; D010212:Papilloma / Q000601:surgery; D011230:Precancerous Conditions / Q000473:pathology / Q000601:surgery*
vernacular_title: Chirurgische Prophylaxe bei Präcancerosen und nicht invasiven Carcinomen der Mamma.