title: A cloned sequence, p82H, of the alphoid repeated DNA family found at the centromeres of all human chromosomes.
abstract: Clone p82H is a human DNA sequence which hybridises in situ exclusively to the centromeric regions of all human chromosomes. It is composed of approximately 14 tandemly repeated variants of a basic 172 bp sequence, and is related to the alphoid family. The organisation of the family of cross-hybridising sequences, detected by the clone p82H, is described both in the human genome and on certain chromosomes, and its relationship to known sequence families is discussed.
mesh_terms: D001483:Base Sequence; D002503:Centromere / Q000648:ultrastructure*; D002875:Chromosomes / Q000648:ultrastructure*; D002877:Chromosomes, Human / Q000648:ultrastructure*; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics*; D004262:DNA Restriction Enzymes; D004251:DNA Transposable Elements; D004926:Escherichia coli / Q000235:genetics; D006801:Humans; D006822:Hybrid Cells / Q000166:cytology; D008297:Male; D009693:Nucleic Acid Hybridization; D012091:Repetitive Sequences, Nucleic Acid; D013094:Spermatozoa
chemical_list: D004251:DNA Transposable Elements; D004247:DNA; D004262:DNA Restriction Enzymes