title: [Progressive multifocal leukoencephalopathy in hemophilia A. Is there a relation to AIDS?].
abstract: Progressive multifocal leukencephalopathy (PML) due to Papovavirus is usually combined with a cellular immunodeficiency as a consequence either of a neoproliferative disease or of medical treatment. In the first description of a case of PML in combination with substituted hemophilia A with no known cellular immunodeficiency, possible pathogenetic relations to factor VIII substitution as well as to AIDS, caused by HTLV-III virus, are discussed.
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000473:pathology*; D000328:Adult; D001253:Astrocytes / Q000648:ultrastructure; D001921:Brain / Q000473:pathology; D006467:Hemophilia A / Q000473:pathology*; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D007968:Leukoencephalopathy, Progressive Multifocal / Q000473:pathology*; D008297:Male; D008854:Microscopy, Electron; D009186:Myelin Sheath / Q000648:ultrastructure; D009836:Oligodendroglia / Q000648:ultrastructure; D014057:Tomography, X-Ray Computed
vernacular_title: Progressive multifokale Leukenzephalopathie bei Hämophilie A. Besteht ein Zusammenhang mit AIDS?