The central auditory conduction at term date and three months after birth. I. Composite group averages of brainstem (ABR), middle latency (MLR) and auditory cortical responses (ACR).
We are investigating the maturation of auditory evoked responses, as a potential diagnostic tool for the neurological examination of premature infants at the Intensive Care Unit for Prematures. In this communication we report the group composite averages of the BMC-ARs in a group of 25 mature and healthy newborns with a follow-up at 3 months of age. The ABRs showed a remarkable variability in wave I latency, with a relatively stable I-V central conduction time (CCT) of the brainstem. The ipsilateral II-V CCT does not differ appreciably from the contralateral II-V CCT. The MLR components NoPoNa and Nb, Nc, Nd are easy to identify in the group averages. Voltage asymmetry between stimulated versus non-stimulated side is slight but persistent in the newborn period as well as at 3 months of age. The group averaged ACRs, show an early complex within the latency reach of 100 ms and a slow W-shaped late complex, most distinct at 3 months. The results indicate that the protocol as applied constitutes a tool for the testing of conduction function of the auditory afference in newborns, even beyond the level of the brainstem. Group averaging offers a method to determine the intragroup stability of evoked potentials under investigation.
D000161:Acoustic Stimulation; D001303:Auditory Cortex / Q000502:physiology*; D001306:Auditory Pathways / Q000502:physiology; D001933:Brain Stem / Q000502:physiology*; D002657:Child Development; D004292:Dominance, Cerebral / Q000502:physiology; D005072:Evoked Potentials, Auditory; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011930:Reaction Time / Q000502:physiology*; D012016:Reference Values; D009435:Synaptic Transmission