title: The use of DNA polymorphisms demonstrated by means of the HLA system.
abstract: The advances reached by using DNA polymorphisms (restriction fragment length polymorphisms) in blood group serology are demonstrated by means of the HLA system. The potentialities for various applications (e.g. better definition of alloantigens, association with diseases, paternity testing, forensic medicine or genetic counselling) are mentioned.
mesh_terms: D004247:DNA / Q000235:genetics*; D004262:DNA Restriction Enzymes; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000235:genetics; D005815:Genetic Code; D005819:Genetic Markers; D005838:Genotype; D006680:HLA Antigens / Q000145:classification / Q000235:genetics*; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D015236:HLA-C Antigens; D000949:Histocompatibility Antigens Class II / Q000235:genetics; D006801:Humans; D009103:Multiple Sclerosis / Q000097:blood / Q000235:genetics; D011110:Polymorphism, Genetic; D011296:Prenatal Diagnosis
chemical_list: D005819:Genetic Markers; D006680:HLA Antigens; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D015236:HLA-C Antigens; D000949:Histocompatibility Antigens Class II; D004247:DNA; D004262:DNA Restriction Enzymes