title: Identification and characterization of human erythrocyte muscarinic receptors.
abstract: Cholinergic muscarinic but not nicotinic receptors could be detected on the outer surface of the human red blood cell membrane by direct labelled ligand binding. This 3H-QNB binding could be inhibited by atropine. The erythrocyte cholinergic receptor was similar to brain muscarinic receptor in regard to stimulation of cGMP production.
mesh_terms: D002122:Calcium Chloride / Q000494:pharmacology; D002217:Carbachol / Q000494:pharmacology; D006152:Cyclic GMP / Q000097:blood; D004533:Egtazic Acid / Q000494:pharmacology; D004910:Erythrocyte Membrane / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D011813:Quinuclidinyl Benzilate / Q000097:blood; D011976:Receptors, Muscarinic / Q000378:metabolism* / Q000502:physiology
chemical_list: D011976:Receptors, Muscarinic; D004533:Egtazic Acid; D011813:Quinuclidinyl Benzilate; D002217:Carbachol; D006152:Cyclic GMP; D002122:Calcium Chloride