title: [Components of the outer membrane of Yersinia pseudotuberculosis and their role in the pathogenesis of pseudotuberculosis].
abstract: The pore-forming protein, lipopolysaccharide-protein complex and lipopolysaccharide of Y. pseudotuberculosis outer membrane have been shown to participate in the penetration of the bacteria into the cells of the macroorganism, to produce a toxic effect on these cells and to enhance the ingesting activity of macrophages in small doses, while suppressing it in large doses. When introduced parenterally, protein induces a more pronounced clinical picture of specific reactive hepatitis in experimental animals and greater changes in their kidneys than the lipopolysaccharide--protein complex.
mesh_terms: D000268:Adhesiveness; D000327:Adsorption; D000818:Animals; D001425:Bacterial Outer Membrane Proteins / Q000633:toxicity*; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D006168:Guinea Pigs; D006801:Humans; D008070:Lipopolysaccharides / Q000633:toxicity*; D008264:Macrophages / Q000187:drug effects / Q000382:microbiology; D051379:Mice; D018272:Porins; D013997:Time Factors; D015007:Yersinia / Q000472:pathogenicity*; D015009:Yersinia Infections / Q000209:etiology*; D015012:Yersinia pseudotuberculosis Infections / Q000209:etiology* / Q000382:microbiology
chemical_list: D001425:Bacterial Outer Membrane Proteins; D008070:Lipopolysaccharides; D018272:Porins
vernacular_title: Komponenty naruzhnoĭ membrany Yersinia pseudotuberculosis i ikh rol' v patogeneze psevdotuberkuleza.