title: Stress as a principal cause of calcium oxalate urolithiasis.
abstract: Epidemiological information on calcium oxalate urolithiasis is reviewed and interpreted according to a proposed stress-related mechanism. This mechanism involves hypothalamo-hypophyseal secretion firstly of vasopressin which acts directly to produce hypertonic urine and secondly of adrenocorticotropin which acts via a secondary hyperparathyroid mechanism to raise serum calcium levels.
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000502:physiology; D002118:Calcium / Q000097:blood; D002129:Calcium Oxalate; D005260:Female; D006801:Humans; D007031:Hypothalamus / Q000503:physiopathology; D008297:Male; D010902:Pituitary Gland / Q000503:physiopathology; D012959:Socioeconomic Factors; D013312:Stress, Physiological / Q000150:complications* / Q000503:physiopathology; D014545:Urinary Calculi / Q000453:epidemiology / Q000209:etiology*; D014667:Vasopressins / Q000502:physiology
chemical_list: D014667:Vasopressins; D002129:Calcium Oxalate; D000324:Adrenocorticotropic Hormone; D002118:Calcium