Adult T-cell leukemia-like disease in monkey naturally infected with simian retrovirus related to human T-cell leukemia virus type I.
Spontaneous T-cell leukemia similar to human adult T-cell leukemia (ATL) was found in an African green monkey naturally infected with simian retrovirus closely related to human T-cell leukemia virus type I (HTLV-I). Monoclonal integration of the simian retrovirus was detected in the primary leukemic cells, suggesting an association of the retrovirus with ATL-like leukemia in the monkey.
D000818:Animals; D002522:Chlorocebus aethiops / Q000382:microbiology; D017977:Deltaretrovirus / Q000302:isolation & purification*; D005260:Female; D007938:Leukemia / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D008198:Lymph Nodes / Q000473:pathology; D008992:Monkey Diseases / Q000378:metabolism* / Q000473:pathology; D012190:Retroviridae / Q000302:isolation & purification*; D013601:T-Lymphocytes / Q000473:pathology