title: Proliferative responses to human cytomegalovirus in lymphocyte cultures of male homosexuals.
abstract: 29 healthy adults and 32 male homosexuals were investigated for their humoral and cellular immunity against human cytomegalovirus (HCMV). In contrast to 30% of the controls, all homosexuals had HCMV serum antibodies. In addition, 84% of the homosexuals reacted positively in HCMV induced in vitro lymphocyte proliferation as compared to 66% of the controls. The study group also showed significantly higher mean reactivities in the lymphoproliferative response towards HCMV. In the group of homosexuals, a correlation could be established between the humoral and cellular immune reactivity to HCMV.
mesh_terms: D000328:Adult; D003587:Cytomegalovirus / Q000276:immunology*; D005260:Female; D006716:Homosexuality; D006801:Humans; D008206:Lymphatic Diseases / Q000276:immunology* / Q000382:microbiology; D008213:Lymphocyte Activation; D008297:Male