title: [Cytomegalovirus infection after kidney transplantation--importance of the primary infection].
abstract: Even though for many reasons (shortage of organs, histocompatibility, lack of time to await the results) an organ transplantation from a sero-positive donor to a sero-negative recipient will not be unavailable, CMV-serology should be checked as early as possible, if possible even before transfusions or their donors since the virus remains infectious over several weeks in the leucocytes. The prophylactic use of hyperimmunoglobulin is justified in cases where organs or blood from sero-positive donors are given to sero-negative immunosuppressed patients because complications arising from the infection can be life-threatening in these patients.
mesh_terms: D000914:Antibodies, Viral / Q000627:therapeutic use; D001379:Azathioprine / Q000627:therapeutic use; D003524:Cyclosporins / Q000627:therapeutic use; D003587:Cytomegalovirus / Q000276:immunology / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000517:prevention & control*; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D016030:Kidney Transplantation; D008214:Lymphocytes / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D065227:Transfusion Reaction; D014779:Virus Replication
chemical_list: D000914:Antibodies, Viral; D003524:Cyclosporins; D001379:Azathioprine
vernacular_title: Zytomegalievirusinfektion nach Nierentransplantation--die Bedeutung der primären Infektion.