Intrachromosomal insertion of chromosome 13 in a family with psychosis and mental subnormality.
A family is reported in which an apparently balanced intrachromosomal insertion of chromosome 13, inv ins(13)(q21.3q32q31), was detected in four members, three of whom also show psychiatric disorder including mental subnormality, personality defects and frank psychosis. The possible effects of the insertion are considered.
D000328:Adult; D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D002874:Chromosome Mapping; D002882:Chromosomes, Human, Pair 13; D004251:DNA Transposable Elements; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics*; D010375:Pedigree; D011618:Psychotic Disorders / Q000235:genetics*
D004251:DNA Transposable Elements