Hepatocellular carcinoma and focal nodular hyperplasia associated with norethandrolone-therapy: a case report.
A 33-year-old woman was treated for severe aplastic anemia with norethandrolone over a period of four years, with a cumulative dose of 25 g. In the fifth year of therapy two intrahepatic tumors were detected and were classified as hepatocellular carcinoma and as focal nodular hyperplasia, respectively.
D000328:Adult; D000741:Anemia, Aplastic / Q000188:drug therapy; D006528:Carcinoma, Hepatocellular / Q000139:chemically induced*; D005260:Female; D006801:Humans; D006965:Hyperplasia; D008099:Liver / Q000187:drug effects / Q000473:pathology*; D008113:Liver Neoplasms / Q000139:chemically induced*; D009639:Norethandrolone / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
D009639:Norethandrolone