Platelet alpha 2-adrenoreceptor binding in elderly depressed patients.
Specific binding of 3H-clonidine to platelet membranes was measured in depressed elderly patients and in an elderly control group. Maximum specific binding was significantly higher in depressed patients than in the control group, whereas the binding affinity was not significantly different.
D000367:Age Factors; D000368:Aged; D001792:Blood Platelets / Q000378:metabolism*; D003000:Clonidine / Q000378:metabolism*; D003866:Depressive Disorder / Q000097:blood / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D011942:Receptors, Adrenergic, alpha / Q000378:metabolism*
D011942:Receptors, Adrenergic, alpha; D003000:Clonidine