[History of 2 cells in T cell lymphomas and leukemias: the cerebriform Lutzner cell in Sézary syndrome and the polylobulated or polypetaloid cell in acute T cell lymphoma/leukemia].
In normal blood, there appears to be two similar but different subsets of T-lymphocytes present: (1) the cerebriform or convoluted Sézary-syndrome Lutzner cell, which may give rise to cutaneous T-cell lymphoma; (2) the polypetaloid or lobated acute T-cell lymphoma/leukemia (ATLL) cell, which may give rise to ATLL. Both cell types can be differentiated by their characteristic nuclear shapes.
D000208:Acute Disease; D002467:Cell Nucleus / Q000648:ultrastructure; D017977:Deltaretrovirus; D006801:Humans; D007938:Leukemia / Q000473:pathology*; D008223:Lymphoma / Q000473:pathology*; D009182:Mycosis Fungoides / Q000473:pathology; D012192:Retroviridae Infections / Q000473:pathology*; D012751:Sezary Syndrome / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*; D013601:T-Lymphocytes / Q000145:classification / Q000648:ultrastructure*; D006377:T-Lymphocytes, Helper-Inducer / Q000648:ultrastructure; D050378:T-Lymphocytes, Regulatory / Q000648:ultrastructure
Die Geschichte von zwei Zellen in T-Zell-Lymphomen/Leukämien: Die zerebriforme Lutzner-Zelle beim Sézary-Syndrom (SS) und die polylobulierte oder polypetaloide Zelle beim akuten T-Zell-Lymphom/Leukämie (ATLL).