title: A new allele with abnormal cyclic-AMP phosphodiesterase activity in Phycomyces.
abstract: A mutant of the fungus Phycomyces blakesleeanus (Burgeff), C21 (madA7) that was isolated for its abnormal phototropism (Bergman et al. 1973) carries a secondary mutation pde-1 which is unlinked to the madA gene. The pde-1 allele causes the loss of about 80% of the cAMP phosphodiesterase activity. This allele is not essential for the photoreactions of the mycelium or the sporangiophore, and the bulk activity of the phosphodiesterase appears to play no role in the phototransduction pathway of Phycomyces.
mesh_terms: D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000235:genetics* / Q000378:metabolism; D000483:Alleles; D005838:Genotype; D009090:Mucorales / Q000235:genetics*; D009154:Mutation; D010800:Phycomyces / Q000201:enzymology / Q000235:genetics*
chemical_list: D015105:3',5'-Cyclic-AMP Phosphodiesterases