title: A role of some central neurotransmitter systems in the mechanism of electroconvulsive shock action.
abstract: Behavioral effects of electroconvulsive shock (ECS) on the neurotransmitter systems were studied in relation to the mechanism of action. Repeated ECS, applied to rats, enhanced the behavioral response to dopaminergic, serotonergic and opiate agonists and attenuated the behavioral effects to GABA-ergic antagonists. The same ECS schedule did not significantly alter the behavioral response to alpha 2- and beta-adrenergic agonists and apomorphine-induced stereotypy but significantly potentiated haloperidol-induced catalepsy.
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology*; D004597:Electroshock; D008297:Male; D009043:Motor Activity; D009638:Norepinephrine / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D011941:Receptors, Adrenergic / Q000502:physiology; D011954:Receptors, Dopamine / Q000502:physiology; D011957:Receptors, Opioid / Q000502:physiology; D011985:Receptors, Serotonin / Q000502:physiology; D012640:Seizures / Q000503:physiopathology*; D009435:Synaptic Transmission; D005680:gamma-Aminobutyric Acid / Q000502:physiology
chemical_list: D011941:Receptors, Adrenergic; D011954:Receptors, Dopamine; D011957:Receptors, Opioid; D011985:Receptors, Serotonin; D005680:gamma-Aminobutyric Acid; D009638:Norepinephrine