title: [Effects, in rats, of metapramine and carpipramine on the uptake of catecholamines and serotonin; relationship with 3H-imipramine binding].
abstract: Carpipramine and metapramine inhibited 3H-imipramine binding both added in vitro and administered to the animal. They were inhibitors of NA uptake and they did not modified 5HT uptake. Only carpipramine affected DA release and uptake.
mesh_terms: D000818:Animals; D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D001692:Biological Transport / Q000187:drug effects; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D002352:Carrier Proteins; D003984:Dibenzazepines / Q000494:pharmacology*; D004298:Dopamine / Q000378:metabolism*; D007099:Imipramine / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D009638:Norepinephrine / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D011955:Receptors, Drug; D017981:Receptors, Neurotransmitter / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism*
chemical_list: D014151:Anti-Anxiety Agents; D002352:Carrier Proteins; D003984:Dibenzazepines; D011955:Receptors, Drug; D017981:Receptors, Neurotransmitter; C027775:imipramine receptor; D001569:Benzodiazepines; C012677:metapramine; D012701:Serotonin; C006922:carpipramine; D007099:Imipramine; D004298:Dopamine; D009638:Norepinephrine
vernacular_title: Effets, chez le Rat, de la métapramine et de la carpipramine sur le recaptage des catécholamines et de la sérotonine; relation avec la fixation de l'3H-imipramine.