Brown adipose tissue activity in hypocaloric-diet fed lactating rats.
Hypocaloric diet feeding reduced the mitochondrial protein content and whole tissue GDP-binding in interscapular brown adipose tissue from both virgin and lactating rats. A reduction in brown fat lipoprotein lipase activity was also detected in underfed virgin and lactating animals. These results indicate that lactation in the rat, even though it produces a reduction in brown fat activity, does not impair the capacity of the tissue to respond to a diminished caloric intake by lowering its activity further.
D002001:Adipose Tissue, Brown / Q000502:physiology*; D000818:Animals; D001833:Body Temperature Regulation; D004247:DNA / Q000032:analysis; D004038:Diet, Reducing; D003576:Electron Transport Complex IV / Q000378:metabolism; D002149:Energy Intake; D005260:Female; D006153:Guanosine Diphosphate / Q000378:metabolism; D007774:Lactation; D008928:Mitochondria / Q000378:metabolism; D009929:Organ Size; D010101:Oxygen Consumption; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains
D006153:Guanosine Diphosphate; D004247:DNA; D003576:Electron Transport Complex IV