The inhibitory feedback pathway from the forelimb to C3-C4 propriospinal neurones investigated with natural stimulation.
Light mechanical stimulation of the skin and passive joint movements in the forelimb gave effective activation of interneurones located medially in the C3-C4 segments. Such interneurones may be inhibitory to C3-C4 propriospinal neurones (PNs) and recording from PNs revealed that the stimuli which activated the interneurones evoked inhibition in the PNs. It is postulated that a movement commanded via the C3-C4 PNs evoke impulses in forelimb afferents which by negative feedback control transmission in the C3-C4 PNs and thus govern the execution of the movements.
D000344:Afferent Pathways / Q000502:physiology*; D000818:Animals; D002415:Cats; D005246:Feedback; D005552:Forelimb / Q000294:innervation; D007395:Interneurons / Q000502:physiology; D009046:Motor Neurons / Q000502:physiology; D009132:Muscles / Q000294:innervation*; D009474:Neurons / Q000502:physiology*; D013116:Spinal Cord / Q000502:physiology*; D009435:Synaptic Transmission