Apical and basal-lateral Na/K-ATPase in rat lacrimal gland acinar cells.
The distribution of Na/K-ATPase in rat exorbital lacrimal gland was studied using immunofluorescent localization of an antibody raised against rat kidney Na/K-ATPase. In cryostat sections, intralobular ducts were strongly immunoreactive and acinar cells showed localization on both apical and basal-lateral surfaces. Acinar cells also had strong intracellular reactivity in apical regions. These results are discussed in light of current models of exocrine gland electrolyte secretion.
D000818:Animals; D002462:Cell Membrane / Q000201:enzymology; D005455:Fluorescent Antibody Technique; D007765:Lacrimal Apparatus / Q000166:cytology / Q000201:enzymology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*
D000254:Sodium-Potassium-Exchanging ATPase