Behavioral effects of erythrosine following light exposure.
Three studies were conducted to examine the effects of erythrosine on the activity level of mice in a figure 8 maze. Results of the first study show that activity in a dark maze is not influenced by intraperitoneal doses as high as 1.25 mg/kg. In two additional studies, subjects were subjected to combinations of dye and pre-exposure to blue (Experiment II) or blue and green (Experiment III) light. Light exposure consistently produced increased activity levels. However, there was little evidence of a dye-light interaction effect.
D000818:Animals; D004923:Erythrosine / Q000633:toxicity*; D005106:Exploratory Behavior / Q000187:drug effects*; D005260:Female; D005452:Fluoresceins / Q000633:toxicity*; D005505:Food Coloring Agents / Q000633:toxicity*; D007274:Injections, Intraperitoneal; D008027:Light; D008297:Male; D051379:Mice; D008812:Mice, Hairless; D009043:Motor Activity / Q000187:drug effects*
D005452:Fluoresceins; D005505:Food Coloring Agents; D004923:Erythrosine