[The antibiotic galtamycin. The structure of galtamycinone].
The structure of galtamycinone, a chromophore moiety of galtamycin, a new antitumor antibiotic was determined by spectral analysis, i.e. UV, NMR and mass spectrometry. Galtamycinone was shown to be 1,4,6-trioxy-10 [4 (e), 5 (e)-dioxy-6 (e)-methyl-tetrahydropyran-2(e)-yl]-8-methyl tetracendion-5,12. It represents a new type of anthracycline chromophores containing a C-glycoside bond in its molecule.
D000107:Acetylation; D018943:Anthracyclines; D000903:Antibiotics, Antineoplastic / Q000032:analysis*; D055598:Chemical Phenomena; D002621:Chemistry; D004578:Electron Spin Resonance Spectroscopy; D006027:Glycosides / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009279:Naphthacenes / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet
D018943:Anthracyclines; D000903:Antibiotics, Antineoplastic; D006027:Glycosides; D009279:Naphthacenes; C049641:galtamycin; C049642:galtamycinone
Antibiotik galtamitsin. Stroenie galtamitsinona.