title: Intranasal vaccination of pigs against Aujeszky's disease: comparison with inactivated vaccines in pigs with low maternal antibody titres.
abstract: Intranasal vaccination with an attenuated Aujeszky's disease virus strain was compared with parenteral vaccination with two inactivated virus vaccines, in 10-week-old pigs with low levels of maternal antibody. Intranasal vaccination conferred a much better protection than parenteral vaccination with the two inactivated vaccines against challenge two months later, as evidenced by shorter periods of growth arrest and fever and a greater reduction of virulent virus shedding after challenge-exposure.
mesh_terms: D000281:Administration, Intranasal; D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis*; D011558:Herpesvirus 1, Suid / Q000276:immunology*; D007112:Immunity, Maternally-Acquired; D007273:Injections, Intramuscular / Q000662:veterinary; D009500:Neutralization Tests; D011557:Pseudorabies / Q000517:prevention & control*; D013552:Swine; D013553:Swine Diseases / Q000517:prevention & control*; D014611:Vaccination / Q000662:veterinary*; D014613:Vaccines, Attenuated / Q000008:administration & dosage / Q000276:immunology; D014765:Viral Vaccines / Q000008:administration & dosage / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D014613:Vaccines, Attenuated; D014765:Viral Vaccines