Aplastic crisis and erythema infectiosum (fifth disease) revealing a hereditary spherocytosis in a familial human parvovirus infection.
We report two clinical observations on a father and son, who both presented an aplastic crisis at the same time during a human parvovirus (HPV) infection. This erythroblastopenia revealed hereditary spherocytosis in both patients. The son also had a clinical status of erythema infectiosum (fifth disease). This data shows that HPV may be responsible for these two different pathologies in the same person.
D000328:Adult; D000741:Anemia, Aplastic / Q000150:complications / Q000235:genetics*; D004890:Erythema / Q000150:complications / Q000235:genetics*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007223:Infant; D008297:Male; D010322:Parvoviridae Infections / Q000150:complications / Q000235:genetics*; D013103:Spherocytosis, Hereditary / Q000150:complications / Q000175:diagnosis / Q000235:genetics*
D006454:Hemoglobins