Postnatal development of [3H]yohimbine binding in the olfactory bulb of male and female rats.
A postnatal increase in [3H]yohimbine binding sites was observed in the rat olfactory bulb. The maximal increase in binding site density was between postnatal days 1 and 14 and corresponded to that of peak interneuron (granule and periglomerular) production and maturation, suggesting a possible interneuron location for the alpha 2-adrenoceptors in the rat olfactory bulb. No differences in [3H]yohimbine binding in the olfactory bulb attributable to sex or stage of the estrous cycle were observed.
D000367:Age Factors; D000818:Animals; D004971:Estrus; D005260:Female; D007395:Interneurons / Q000378:metabolism; D008297:Male; D009830:Olfactory Bulb / Q000254:growth & development / Q000378:metabolism*; D009929:Organ Size; D011942:Receptors, Adrenergic, alpha / Q000378:metabolism*; D012737:Sex Factors; D015016:Yohimbine / Q000378:metabolism*
D011942:Receptors, Adrenergic, alpha; D015016:Yohimbine