title: Idiopathic haemorrhagic rupture of the shoulder in destructive disease of the elderly.
abstract: The cases of two patients with hydroxyapatite crystal associated destructive disease of the shoulder are described who have developed gross haemorrhagic effusions with spontaneous joint rupture and extensive soft tissue damage. No collagenase activity was found in the synovial fluid. Other possible mechanisms of the destructive process are discussed.
mesh_terms: D000368:Aged; D005260:Female; D006470:Hemorrhage / Q000209:etiology* / Q000378:metabolism; D006801:Humans; D006882:Hydroxyapatites / Q000032:analysis; D007592:Joint Diseases / Q000150:complications* / Q000378:metabolism; D003012:Microbial Collagenase / Q000378:metabolism; D012422:Rupture, Spontaneous; D012785:Shoulder Joint / Q000032:analysis*; D013582:Synovial Fluid / Q000032:analysis
chemical_list: D006882:Hydroxyapatites; D003012:Microbial Collagenase