[HLA typing in patients with chronic adenopathies in a population at risk for AIDS].
HLA-A B and DR typing were performed in 77 patients with AIDS related complex (ARC)--69 lymphadenopathy associated syndrome and 8 thrombocytopenic purpura LAV/HTLV III related--and 21 symptom free homosexual males. A significant increase in the frequency of HLA DR5 antigen was observed in patients with ARC mainly in purpura thrombocytopenic patients. We suggest that increase of HLA DR5 antigen support the view that DR5 antigen could be one of the factors necessary at the spreading out clinical symptoms.
D000386:AIDS-Related Complex / Q000208:ethnology / Q000235:genetics*; D044383:Black People; D004198:Disease Susceptibility; D006680:HLA Antigens / Q000032:analysis / Q000235:genetics*; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D006684:HLA-DR Antigens / Q000032:analysis; D015805:HLA-DR5 Antigen; D006716:Homosexuality; D006801:Humans; D008297:Male; D010641:Phenotype; D012192:Retroviridae Infections / Q000276:immunology; D012306:Risk; D044465:White People
D006680:HLA Antigens; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D006684:HLA-DR Antigens; D015805:HLA-DR5 Antigen
Typage HLA chez des patients porteurs d'adénopathies chroniques dans une population à risque de SIDA.