Thrombocytopenic purpura following varicella-zoster vaccination.
Acute thrombocytopenia developed 3 weeks after the vaccination of a child with leukemia with V-Z vaccine. This is the first case of postvaccinal thrombocytopenia to be reported following V-Z vaccine. The risk to leukemic children of postvaccinal thrombocytopenia would appear to be less than 1%. Note added in proof: The patient remained seronegative until the eighth month following vaccination. Her FAMA titer then rose to 1:32, probably as a result of exogenous reinfection with V-Z virus.
D019433:Chickenpox Vaccine; D005260:Female; D014645:Herpesvirus 3, Human / Q000276:immunology*; D006801:Humans; D007223:Infant; D007945:Leukemia, Lymphoid / Q000150:complications / Q000276:immunology; D011696:Purpura, Thrombocytopenic / Q000209:etiology*; D014611:Vaccination / Q000009:adverse effects; D014613:Vaccines, Attenuated / Q000009:adverse effects; D014765:Viral Vaccines / Q000009:adverse effects*
D019433:Chickenpox Vaccine; D014613:Vaccines, Attenuated; D014765:Viral Vaccines