Adrenocortical adenoma with Cushing's syndrome in culture.
Two adrenocortical adenomata with Cushing's syndrome were examined employing cell culture methods. The results revealed that the clear-type cells changed into compact-type cells, and that the compact cells played a role in the production and secretion of steroid hormones. Furthermore, it is likely that they underwent fragmentation and produced collagen fibrils.
D000236:Adenoma / Q000150:complications / Q000473:pathology* / Q000648:ultrastructure; D000306:Adrenal Cortex Neoplasms / Q000150:complications / Q000473:pathology* / Q000648:ultrastructure; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D002478:Cells, Cultured; D046508:Culture Techniques / Q000379:methods; D003480:Cushing Syndrome / Q000209:etiology*; D006801:Humans; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D008871:Microvilli / Q000648:ultrastructure; D013256:Steroids / Q000096:biosynthesis
D013256:Steroids; D000324:Adrenocorticotropic Hormone