title: Cardiopulmonary resuscitation. A current perspective.
abstract: Cardiopulmonary resuscitation is effective if established early and coupled with specific therapeutic interventions. Most cardiopulmonary arrest is due to ventricular fibrillation and early defibrillation offers the highest probability of success. External cardiac compression alone is inadequate to provide adequate perfusion to vital organs and, therefore, cannot sustain life unless coupled with advanced therapeutic interventions. Many new techniques for increasing flow have been developed, but have not been established clinically. The American Heart Association guidelines for CPR are still valid and are the basis for our current CPR. A practical perspective is presented whereby the therapeutic interventions are pursued systematically in an expeditious and coordinated fashion so that the key interventions are made within the first 10 to 15 minutes of the arrest.
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D001285:Atropine / Q000627:therapeutic use; D001639:Bicarbonates / Q000627:therapeutic use; D001927:Brain Diseases / Q000517:prevention & control; D002118:Calcium / Q000627:therapeutic use; D002304:Cardiac Pacing, Artificial; D002404:Catheterization; D004554:Electric Countershock; D006323:Heart Arrest / Q000628:therapy; D006336:Heart Massage; D006801:Humans; D007442:Intubation, Intratracheal; D012151:Resuscitation / Q000379:methods*; D012964:Sodium / Q000627:therapeutic use; D017693:Sodium Bicarbonate; D013566:Sympathomimetics / Q000627:therapeutic use; D013610:Tachycardia / Q000628:therapy; D014680:Veins; D014693:Ventricular Fibrillation / Q000628:therapy
chemical_list: D000889:Anti-Arrhythmia Agents; D001639:Bicarbonates; D013566:Sympathomimetics; D001285:Atropine; D017693:Sodium Bicarbonate; D012964:Sodium; D002118:Calcium