Chronic postcolectomy pericholangitis and cholangiocarcinoma.
Two patients with long-standing pericholangitis developed unresectable cholangiocarcinoma after colectomy for chronic ulcerative colitis. The natural history of their illnesses suggest that chronic inflammation of small bile ducts in ulcerative colitis may be a precursor of biliary cancer and may also account for the increased incidence of this tumor in the colitis population.
D002759:Adenoma, Bile Duct / Q000209:etiology*; D000368:Aged; D001650:Bile Duct Neoplasms / Q000209:etiology*; D001706:Biopsy; D002761:Cholangitis / Q000150:complications*; D002908:Chronic Disease; D003082:Colectomy; D003093:Colitis, Ulcerative / Q000150:complications* / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D008099:Liver / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications