[Transitory hypothyroidism of the newborn infant following amniofetography with an iodine-containing contrast medium].
In the foetus and neonate the thyroid follicular cells are immature and hence incapable of protecting the organism against an iodide-induced inhibition of hormone synthesis (Wolff-Chaikoff effect). Thus, an iodide excess during pregnancy can lead to transient hypothyroidism in the foetus and neonate. Transient hypothyroidism due to iodide toxicity following amniofoetography in the newborn period is described.
D003287:Contrast Media / Q000009:adverse effects*; D005260:Female; D005317:Fetal Growth Retardation / Q000000981:diagnostic imaging*; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000139:chemically induced*; D007231:Infant, Newborn; D007459:Iodized Oil / Q000009:adverse effects*; D011247:Pregnancy; D011296:Prenatal Diagnosis; D011859:Radiography; D013972:Thyrotropin / Q000097:blood
D003287:Contrast Media; D007459:Iodized Oil; D013972:Thyrotropin
Transitorische Hypothyreose des Neugeborenen nach Amniofetographie mit jodhaltigem Kontrastmittel.