[Bowenoid papulosis and carcinoma in situ of the cervix uteri in sex partners. An example of the transmissibility of HPV-16 infection].
The development of bowenoid papules in a 20-year-old man and a carcinoma in situ of the portio uteri of the 22-year-old female sexual partner is reported. In both lesions HPV-16 DNA could be detected by molecular biological means. This observation led us to the conclusion that HPV 16 had been transmitted sexually. The same seems to be true for HPV-11-induced condylomata acuminata, which appeared on the external genitalia of both patients after recuperation from the HPV-16-induced lesions and conisation treatment. The clinical significance of this observation and its consequences for dermatologists and gynecologists are discussed.
D000328:Adult; D001913:Bowen's Disease / Q000209:etiology* / Q000601:surgery; D002278:Carcinoma in Situ / Q000209:etiology* / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D027383:Papillomaviridae / Q000302:isolation & purification; D010412:Penile Neoplasms / Q000209:etiology* / Q000601:surgery; D012725:Sexual Behavior; D012878:Skin Neoplasms / Q000209:etiology* / Q000601:surgery; D014412:Tumor Virus Infections / Q000601:surgery / Q000635:transmission*; D002583:Uterine Cervical Neoplasms / Q000209:etiology* / Q000601:surgery
Bowenoide Papulose und Carcinoma in situ der Cervix uteri bei Sexualpartnern. Ein Beispiel für die Ubertragbarkeit der HPV-16-Infektion.