Resolution of the clinical features of tyrosinemia following orthotopic liver transplantation for hepatoma.
The clinical history before transplantation and subsequent clinical and biochemical course of 3 children and one adult with hereditary tyrosinemia treated by orthotopic hepatic transplantation is described. All four patients are now free of their previous dietary restrictions and appear to be cured of both their metabolic disease and their hepatic neoplasm.
D000328:Adult; D000592:Amino Acid Metabolism, Inborn Errors / Q000150:complications / Q000628:therapy*; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000628:therapy*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications / Q000628:therapy*; D016031:Liver Transplantation; D014443:Tyrosine / Q000097:blood*
D014443:Tyrosine