Inclusion body myositis and systemic lupus erythematosus.
Inclusion body myositis (IBM) has been recognized as a distinct type of idiopathic inflammatory myopathy. Previous reports have emphasized the absence of immunologic abnormalities and lack of response to corticosteroid therapy in patients with IBM. We report a case of IBM associated with systemic lupus erythematosus and modest response of the myopathy to corticosteroid therapy. The clinical and immunologic features of IBM are more diverse than previously appreciated.
D003599:Cytoskeleton / Q000648:ultrastructure; D005260:Female; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008875:Middle Aged; D009220:Myositis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use
D011241:Prednisone