Drug-induced photosensitivity: phototoxic and photoallergic reactions--a few molecular aspects.
Drug-induced photosensitivity involves mainly phototoxic and photoallergic reactions. The main features of phototoxic and photoallergic reactions are presented and some molecular aspects involved in the mechanisms leading to an adverse skin response are illustrated with examples.
D000818:Animals; D000941:Antigens / Q000276:immunology; D002707:Chlordiazepoxide / Q000009:adverse effects; D004247:DNA; D005609:Free Radicals; D011564:Furocoumarins / Q000009:adverse effects; D006801:Humans; D008027:Light; D010100:Oxygen; D010640:Phenothiazines / Q000009:adverse effects; D010777:Photochemistry; D010787:Photosensitivity Disorders / Q000139:chemically induced* / Q000175:diagnosis / Q000276:immunology; D011422:Propionates / Q000009:adverse effects; D013449:Sulfonamides / Q000009:adverse effects; D013481:Superoxides; D013997:Time Factors; D014466:Ultraviolet Rays
D000941:Antigens; D005609:Free Radicals; D011564:Furocoumarins; D010640:Phenothiazines; D011422:Propionates; D013449:Sulfonamides; D013481:Superoxides; C011677:benoxaprofen; D002707:Chlordiazepoxide; D004247:DNA; D010100:Oxygen