Influences of the chemical structure on the activity of new inhibitory compounds of the angiotensin-converting enzyme.
The ACE inhibitory activity of some perimidines, chinazolinones and amidinohydrazones is described. Relations were found between the chemical structure and the inhibitory activity on the ACE.
D000578:Amidines / Q000494:pharmacology; D000806:Angiotensin-Converting Enzyme Inhibitors; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D006835:Hydrazones / Q000494:pharmacology; D011799:Quinazolines / Q000494:pharmacology; D013329:Structure-Activity Relationship; D013552:Swine
D000578:Amidines; D000806:Angiotensin-Converting Enzyme Inhibitors; D006835:Hydrazones; D011799:Quinazolines