title: [cAMP-dependent protein phosphorylation and its regulatory role in the cell].
abstract: Literary data are reviewed on the role of the cAMP-dependent phosphorylation of proteins in the regulation of cell metabolism, membrane permeability, and muscle contraction. It is suggested that a low cAMP level in the tumor and other actively proliferating cells may be associated with a raised exit of cAMP from cells into the surrounding medium because of the increased phosphorylation of the membrane proteins of these cells.
mesh_terms: D000818:Animals; D001692:Biological Transport; D002453:Cell Cycle; D002455:Cell Division; D002463:Cell Membrane Permeability; D002471:Cell Transformation, Neoplastic / Q000378:metabolism; D002868:Chromosomal Proteins, Non-Histone / Q000378:metabolism; D000242:Cyclic AMP / Q000378:metabolism*; D006019:Glycolysis; D006657:Histones / Q000378:metabolism; D007527:Isoenzymes / Q000378:metabolism; D008066:Lipolysis; D009119:Muscle Contraction; D010766:Phosphorylation; D011494:Protein Kinases / Q000378:metabolism; D011506:Proteins / Q000378:metabolism*; D011817:Rabbits
chemical_list: D002868:Chromosomal Proteins, Non-Histone; D006657:Histones; D007527:Isoenzymes; D011506:Proteins; D000242:Cyclic AMP; D011494:Protein Kinases
vernacular_title: tsAMF-zavisimoe fosforilirovanie belkov i ego reguliatornaia rol' v kletke.