title: The occurrence of cyclic AMP in archaebacteria.
abstract: Cyclic AMP was found in species representative of the three major groups of the archaebacteria. In Methanobacterium thermoautotrophicum starvation for H2 led to a significant increase in cellular cAMP. The findings suggest that the occurrence of cAMP antedates the divergence of the major kingdoms of biology; the observations also imply that cAMP constitutes a very early regulatory molecule.
mesh_terms: D001105:Archaea / Q000032:analysis*; D001419:Bacteria / Q000032:analysis*; D000242:Cyclic AMP / Q000032:analysis*; D019605:Euryarchaeota / Q000032:analysis; D006217:Halobacterium / Q000032:analysis; D006859:Hydrogen
chemical_list: D006859:Hydrogen; D000242:Cyclic AMP