Indirect immunofluorescence assay for the detection of hepatitis A virus-specific serum immunoglobulins.
Hepatitis A virus-specific BSC-1 cells were used for the detection of serum immunoglobulins to hepatitis A virus by indirect immunofluorescence. Of 150 serum samples tested, specific immunoglobulin M was detected only in patients with serologically confirmed acute hepatitis A, while specific immunoglobulin G was detected in patients with acute or past clinical hepatitis A as well as many patients with no known history of hepatitis.
D000914:Antibodies, Viral / Q000032:analysis*; D000918:Antibody Specificity; D005455:Fluorescent Antibody Technique; D006506:Hepatitis A / Q000175:diagnosis; D006507:Hepatovirus / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M