Fatal adenovirus pneumonia in two newborn infants, one case caused by adenovirus type 30.
Adenovirus rarely causes pneumonia in the newborn infant. We added 2 cases of fatal adenovirus neonatal pneumonia to the 3 cases previously reported. One of our cases was caused by adenovirus type 30, which is not previously known to be a pathogen. While the pneumonia could have been acquired in the nursery, the presence of chorioamnionitis and mixed infection with group B beta-hemolytic streptococcus suggests that an ascending infection from the birth canal might be another mode of transmission for neonatal adenovirus pneumonia.
D000257:Adenoviridae Infections / Q000473:pathology*; D000258:Adenovirus Infections, Human / Q000150:complications / Q000382:microbiology / Q000473:pathology* / Q000635:transmission; D000260:Adenoviruses, Human / Q000145:classification / Q000302:isolation & purification / Q000648:ultrastructure; D002821:Chorioamnionitis / Q000150:complications / Q000382:microbiology; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000382:microbiology; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D011024:Pneumonia, Viral / Q000382:microbiology / Q000473:pathology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology; D013290:Streptococcal Infections / Q000150:complications / Q000382:microbiology; D013292:Streptococcus agalactiae / Q000145:classification