[Synthesis and properties of an acyclic analog of 9-deazainosine and related compounds].
An acyclic analogue of 9-deazainosine, 9-(2-hydroxyethoxymethyl)-9-deazahypoxanthine, and related compounds have been synthesized starting from 9-(hydroxyethyl)-9-deazahypoxanthine. The acyclo-9-deazainosine exhibited some cytotoxic activity.
D000970:Antineoplastic Agents; D000998:Antiviral Agents; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D055598:Chemical Phenomena; D002621:Chemistry; D005260:Female; D006801:Humans; D007288:Inosine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D010051:Ovarian Neoplasms / Q000473:pathology; D018139:Simplexvirus / Q000187:drug effects; D013329:Structure-Activity Relationship
D000970:Antineoplastic Agents; D000998:Antiviral Agents; D007288:Inosine
Sintez i svoĭstva atsiklicheskogo analoga 9-dezazainozina i rodstvennykh soedineniĭ.