Myristylation of gag protein in human T-cell leukemia virus type-I and type-II.
We found that p19gag of HTLV-I and p23gag of HTLV-II are myristylated. The p28, which is immunologically cross-reactive with monoclonal antibody against p19gag of HTLV-I was also shown to be myristylated in the HTLV-I-infected cell lines MT-2 and HUT102. However, no myristylated p28 was found in HTLV-II-infected cell lines, Mo and Ton1.
D000911:Antibodies, Monoclonal; D017977:Deltaretrovirus / Q000378:metabolism*; D015683:Gene Products, gag; D009226:Myristates / Q000378:metabolism*; D009227:Myristic Acids / Q000378:metabolism*; D010168:Palmitates / Q000378:metabolism; D011499:Protein Processing, Post-Translational; D012191:Retroviridae Proteins / Q000378:metabolism*
D000911:Antibodies, Monoclonal; D015683:Gene Products, gag; D009226:Myristates; D009227:Myristic Acids; D010168:Palmitates; D012191:Retroviridae Proteins