Blood pressure, erythrocyte sodium and potassium concentrations and Na+K+ATPase activity in children with hypertensive mothers.
Fifty-four children aged 10-15 years were studied. Twenty-two children had mothers who had sustained hypertension after a hypertensive pregnancy (HT) and 17 had normotensive mothers who had previously had a hypertensive pregnancy (NT). A control group consisted of 15 children with normotensive mothers (C). Blood pressure was significantly higher in the HT group in comparison with the C group (P less than 0.01). Erythrocyte sodium (Na+) and potassium (K+) concentrations were similar in all groups and not related to blood pressure. The Na+K+ATPase activity in erythrocyte membranes was lower in the HT group than in the NT group (P less than 0.02), but not significantly different from the C group. There was no statistically significant correlation between Na+K+ATPase activity and blood pressure.
D000293:Adolescent; D000328:Adult; D001693:Biological Transport, Active; D001794:Blood Pressure; D002648:Child; D004912:Erythrocytes / Q000032:analysis / Q000201:enzymology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000235:genetics* / Q000378:metabolism; D008297:Male; D011188:Potassium / Q000097:blood*; D012964:Sodium / Q000097:blood*; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*
D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase; D011188:Potassium