Superoxide anion, superoxide dismutase and lipid peroxidation in the murine macrophage cell line C4M phi.
A remarkable increase in the production of superoxide radicals and SOD activity was measured in suspension of the murine macrophage cell line C4M phi treated with Lentinan (4-10 X 10(3) micrograms/5 X 10(6) cells). In activated macrophages the decrease of lipid peroxidation could be interpreted as a consequence of enhanced SOD activity.
D000818:Animals; D002460:Cell Line; D008054:Lipid Peroxides / Q000378:metabolism*; D008262:Macrophage Activation; D008264:Macrophages / Q000378:metabolism*; D008315:Malondialdehyde / Q000378:metabolism; D051379:Mice; D013482:Superoxide Dismutase / Q000378:metabolism; D013481:Superoxides / Q000378:metabolism*
D008054:Lipid Peroxides; D013481:Superoxides; D008315:Malondialdehyde; D013482:Superoxide Dismutase