title: Activity of 5'-nucleotidase, AMP deaminase, adenosine deaminase, acid and alkaline phosphatase and nucleotide pyrophosphatase in human thyroid.
abstract: The activity of 5'-nucleotidase, AMP deaminase, adenosine deaminase, acid phosphatase, alkaline phosphatase and nucleotide pyrophosphatase was assayed in human thyroid glands. The 5'-nucleotidase activity was higher than that of AMP deaminase which suggested that AMP undergoes degradation primarily as a result of dephosphorylation in thyroid tissue. A high acid phosphatase activity was noted as compared to that of alkaline phosphatase activity. In toxic goitre the increase in adenosine deaminase and acid phosphatase was observed together with the decrease in pyrophosphatase activity.
mesh_terms: D015720:5'-Nucleotidase; D000659:AMP Deaminase / Q000378:metabolism*; D000135:Acid Phosphatase / Q000378:metabolism*; D000243:Adenosine Deaminase / Q000378:metabolism*; D000469:Alkaline Phosphatase / Q000378:metabolism*; D001344:Autopsy; D006801:Humans; D007700:Kinetics; D009700:Nucleoside Deaminases / Q000378:metabolism*; D009708:Nucleotidases / Q000378:metabolism*; D009709:Nucleotide Deaminases / Q000378:metabolism*; D011755:Pyrophosphatases / Q000378:metabolism*; D013961:Thyroid Gland / Q000201:enzymology* / Q000473:pathology
chemical_list: D009708:Nucleotidases; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D015720:5'-Nucleotidase; D009700:Nucleoside Deaminases; D009709:Nucleotide Deaminases; D000243:Adenosine Deaminase; D000659:AMP Deaminase; D011755:Pyrophosphatases; C021899:nucleotide pyrophosphatase