title: Leukocytes and tissue injury: the use of eicosapentaenoic acid in the control of white cell activation.
abstract: Eicosapentaenoic acid enriched diet may reduce the severity of acute inflammatory reactions by decreasing the synthesis of dienoic prostanoids and tetraenoic leukotrienes. The findings suggest that a nutritional approach to anti-inflammatory therapy is an interesting possibility deserving further studies.
mesh_terms: D000818:Animals; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000378:metabolism; D015118:Eicosapentaenoic Acid / Q000494:pharmacology*; D007249:Inflammation / Q000276:immunology*; D007962:Leukocytes / Q000187:drug effects* / Q000276:immunology; D007975:Leukotriene B4 / Q000378:metabolism; D051381:Rats; D013189:SRS-A / Q000378:metabolism
chemical_list: D001095:Arachidonic Acids; D013189:SRS-A; D007975:Leukotriene B4; D016718:Arachidonic Acid; D015118:Eicosapentaenoic Acid