[Reversible accumulation of double- and single-strand breaks of DNA during transition of cells into the quiescent stage].
The technique of neutral elution has been used to study DNA fragmentation in SV-40-transformed Hungarian hamster fibroblasts of 4/21 strain. Accumulation of DNA double-strand breaks was observed in growth-arrested cells. The breaks were repaired after the growth resumed. It is suggested that double-strand breaks are a sum of one-strand breaks.
D000818:Animals; D002455:Cell Division; D002472:Cell Transformation, Viral; D006224:Cricetinae; D004247:DNA; D004260:DNA Repair; D004277:DNA, Single-Stranded; D066298:In Vitro Techniques; D013539:Simian virus 40
D004277:DNA, Single-Stranded; D004247:DNA
Obratimoe nakoplenie dvu- i odno-nitevykh razryvov DNK pri perekhode kletok c sostoianie pokoia.