title: Prevalence of antibody to human calicivirus in Japan and Southeast Asia determined by radioimmunoassay.
abstract: Three hundred ninety single sera from adults in Japan, Indonesia, Singapore, and Papua New Guinea were tested for antibodies to human calicivirus (HCV) by a radioimmunoassay blocking test. A high prevalence of antibodies was observed in samples collected in Japan and Southeast Asia. Of 240 serum specimens collected from five districts in Japan, 209 (87.1%) were positive for HCV antibodies. No striking difference in the prevalence of the antibody was seen among those districts. In sera collected in Southeast Asia, 84.0% (126 of 150) had antibodies to HCV (70% [35 of 50] in Singapore, 88% [44 of 50] in Indonesia, and 94% [47 of 50] in Papua New Guinea). These results indicate that HCV is a common infectious agent in Japan and Southeast Asia.
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D002139:Caliciviridae / Q000276:immunology*; D005260:Female; D006801:Humans; D007214:Indonesia; D007564:Japan; D008297:Male; D010219:Papua New Guinea; D010850:Picornaviridae Infections / Q000453:epidemiology; D011863:Radioimmunoassay; D012846:Singapore
chemical_list: D000914:Antibodies, Viral