Correlation between high susceptibility to AIDS virus and surface expression of OKT-4 antigen in HTLV-I-positive cell lines.
Most human T-cell lymphotropic virus type I (HTLV-I)-carrying cell lines possess high susceptibility to AIDS retrovirus. This high permissiveness was clearly correlated with the amount of OKT-4 molecules, the possible receptor for AIDS retrovirus, expressed on the cell surface of HTLV-I-bearing cell lines. However, no correlation was noted in HTLV-I-negative cell lines.
D000954:Antigens, Surface / Q000032:analysis*; D000956:Antigens, Viral / Q000032:analysis; D002460:Cell Line; D002472:Cell Transformation, Viral; D017977:Deltaretrovirus / Q000276:immunology* / Q000472:pathogenicity; D006801:Humans; D014779:Virus Replication
D000954:Antigens, Surface; D000956:Antigens, Viral