[An autopsy case of adult T-cell leukemia with acute hepatic failure].
An autopsy case of ATL with acute hepatic failure is reported. A 39-year-old man born in Miyazaki Prefecture was admitted because of jaundice and general malaise of about 10 days' duration. Palpation of the abdomen revealed moderate hepatomegaly: the patient had clear consciousness. The white cell count was 62,500/mm3, with 34% abnormal lymphocytes having lobulated or convoluted nuclei. Marked liver dysfunction (TB 30.5 mg/dl; GOT 2,740 U; GPT 1,031 U; LDH 3,833 U) was noted. He developed hepatic coma and died of acute hepatic failure on the third hospital day. At autopsy, the enlarged liver weighed 2,000 g and was diffusely infiltrated by ATL cells.
D000208:Acute Disease; D000328:Adult; D017977:Deltaretrovirus; D006501:Hepatic Encephalopathy / Q000209:etiology / Q000473:pathology; D006801:Humans; D007938:Leukemia / Q000150:complications / Q000473:pathology*; D008107:Liver Diseases / Q000209:etiology / Q000473:pathology*; D008297:Male; D012192:Retroviridae Infections / Q000150:complications / Q000473:pathology*