Stage-specific DNA methylation in a fungal plant pathogen.
Significantly more 5-methylcytosine residues were found in the DNA from the dormant sclerotia of Phymatotrichum omnivorum than in the DNA from the metabolically active mycelia of the fungus, as shown by high-pressure liquid chromatography of acid-hydrolyzed DNA digests and by restriction of the DNA with the isoschizomers MspI and HpaII. N6-Methyladenine was not detected in GATC sequences in the DNA isolated from either stage.
D044503:5-Methylcytosine; D001482:Base Composition; D002455:Cell Division; D003596:Cytosine / Q000031:analogs & derivatives* / Q000378:metabolism; D004262:DNA Restriction Enzymes; D004271:DNA, Fungal / Q000235:genetics* / Q000302:isolation & purification; D005658:Fungi / Q000254:growth & development / Q000502:physiology*; D008745:Methylation
D004271:DNA, Fungal; D044503:5-Methylcytosine; D003596:Cytosine; D004262:DNA Restriction Enzymes