title: Epidermal growth factor, its receptor, and related proteins.
abstract: An interesting aspect of the developments forthcoming from the study of cell growth control by growth factors is the structural and functional homologies that have been found to exist between growth factors or their receptors and other molecules. The epidermal growth factor (EGF) system has been particularly fruitful in this regard. The information in this article is meant to summarize the relationships that have been recently described between EGF and other EGF-like molecules and between the EGF receptor and related macromolecules.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002455:Cell Division; D002460:Cell Line; D003001:Cloning, Molecular; D004247:DNA; D004815:Epidermal Growth Factor / Q000235:genetics / Q000378:metabolism / Q000494:pharmacology; D066246:ErbB Receptors; D006801:Humans; D009856:Oncogene Proteins, Viral / Q000032:analysis / Q000235:genetics; D010455:Peptides / Q000378:metabolism / Q000494:pharmacology; D010766:Phosphorylation; D011494:Protein Kinases / Q000378:metabolism; D011498:Protein Precursors; D011956:Receptors, Cell Surface / Q000032:analysis / Q000235:genetics / Q000378:metabolism; D015291:Transforming Growth Factors; D014616:Vaccinia virus / Q000235:genetics / Q000378:metabolism; D014764:Viral Proteins / Q000032:analysis / Q000235:genetics / Q000494:pharmacology
chemical_list: D009856:Oncogene Proteins, Viral; D010455:Peptides; D011498:Protein Precursors; D011956:Receptors, Cell Surface; D014764:Viral Proteins; D004815:Epidermal Growth Factor; D015291:Transforming Growth Factors; D004247:DNA; D011494:Protein Kinases; D066246:ErbB Receptors