title: Non-resolution of pelvic sonographic abnormality after chemotherapy for persistent trophoblastic disease--a word of caution.
abstract: A case of persistent trophoblastic disease (PTD) is presented in whom pelvic sonography demonstrated persistent uterine abnormality and dilated adnexal vessels after cessation of chemotherapy. Hysterectomy was performed on account of subsequent uterine bleeding. A viable tumour was not demonstrated in the hysterectomy specimen. In the absence of haemorrhagic complications persistent sonographic abnormality should not necessarily indicate hysterectomy, especially when hCG levels are normal.
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D006063:Chorionic Gonadotropin / Q000097:blood; D005260:Female; D006801:Humans; D007044:Hysterectomy; D011247:Pregnancy; D014328:Trophoblastic Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D014463:Ultrasonography; D014592:Uterine Hemorrhage / Q000209:etiology; D014594:Uterine Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D006063:Chorionic Gonadotropin