[Polyneuropathy and residual insulin secretion in diabetes mellitus type I].
In 145 patients suffering from type-I-diabetes with or without signs or symptoms of polyneuropathy basal and glucose-glucagon-induced secretion of insulin was determined. Patients without remaining insulin secretion exhibited somewhat more often polyneuropathies, slowing of nerve conduction, or reduced respiratory heart arrhythmia. If diabetes lasts for more than 10 years, insulin secretion ist reduced to such a low level that its may not have any significant preventive capability with respect to polyneuropathy.
D001786:Blood Glucose / Q000378:metabolism; D002096:C-Peptide / Q000097:blood; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000175:diagnosis*; D003929:Diabetic Neuropathies / Q000097:blood / Q000175:diagnosis*; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000097:blood*; D009046:Motor Neurons / Q000502:physiology; D010543:Peroneal Nerve / Q000503:physiopathology; D011115:Polyneuropathies / Q000175:diagnosis*; D009435:Synaptic Transmission
D001786:Blood Glucose; D002096:C-Peptide; D006442:Glycated Hemoglobin; D007328:Insulin
Polyneuropathie und Restinsulinsekretion beim Diabetes mellitus Typ I.