[Cockayne syndrome. Study of a peripheral nerve biopsy].
A sural nerve biopsy was performed in a 10 year-old girl with a Cockayne syndrome. Morphometric and electron microscope studies revealed signs of a chronic demyelinating disease and some dense inclusions in Schwann cells. The significance of these abnormalities is discussed from a review of literature.
D001706:Biopsy; D002648:Child; D003057:Cockayne Syndrome / Q000473:pathology*; D004392:Dwarfism / Q000473:pathology*; D005260:Female; D006801:Humans; D002479:Inclusion Bodies / Q000473:pathology; D008854:Microscopy, Electron; D009186:Myelin Sheath / Q000473:pathology; D009413:Nerve Fibers, Myelinated / Q000473:pathology; D012583:Schwann Cells / Q000473:pathology; D013127:Spinal Nerves / Q000473:pathology*; D013497:Sural Nerve / Q000473:pathology*
Syndrome de Cockayne. Etude d'une biopsie de nerf périphérique.