title: Mistranslation during phenylalanine starvation.
abstract: Starvation for phenylalanine led to leucine misincorporation frequencies of 0.1 and 0.6 at UUC codons in the argI transcript of Escherichia coli, but no detectable misincorporation at a UUU codon. Under similar starvation conditions the relative synthesis of full sized MS2 coat protein, encoded by the RNA virus or a DNA copy, is greatly reduced, preventing analysis of the protein. This reduction in amount is unaffected by a rpsL mutation.
mesh_terms: D001483:Base Sequence; D002213:Capsid / Q000235:genetics; D036022:Capsid Proteins; D003090:Coliphages / Q000235:genetics; D004262:DNA Restriction Enzymes; D004926:Escherichia coli / Q000235:genetics* / Q000254:growth & development; D029968:Escherichia coli Proteins; D005838:Genotype; D007930:Leucine / Q000378:metabolism; D009154:Mutation; D009954:Ornithine Carbamoyltransferase / Q000235:genetics / Q000302:isolation & purification; D010649:Phenylalanine / Q000378:metabolism*; D010957:Plasmids; D014176:Protein Biosynthesis; D016601:RNA-Binding Proteins; D000091243:Ribosomal Protein S9; D013045:Species Specificity
chemical_list: D036022:Capsid Proteins; D029968:Escherichia coli Proteins; D016601:RNA-Binding Proteins; D000091243:Ribosomal Protein S9; C000717190:RpsI protein, E coli; D010649:Phenylalanine; D009954:Ornithine Carbamoyltransferase; D004262:DNA Restriction Enzymes; D007930:Leucine