Structural organization of the mouse proto-myb gene.
Proto-myb is a highly conserved cellular gene that is closely related to v-myb, the transforming gene of the avian myeloblastosis virus. We have isolated lambda clones encompassing 21 kbp of mouse DNA that contains portions of the proto-myb gene. Also, we have isolated a cDNA clone containing a 2.5 kbp insert corresponding to mouse proto-myb mRNA. By analyzing both the cloned DNAs and mouse genome DNA, we have constructed a restriction map for mouse proto-myb that extends over 50 kbp.
D000818:Animals; D009189:Avian Myeloblastosis Virus / Q000235:genetics; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000032:analysis; D004262:DNA Restriction Enzymes; D004274:DNA, Recombinant / Q000032:analysis; D005796:Genes; D005814:Genes, Viral; D051379:Mice; D008807:Mice, Inbred BALB C / Q000235:genetics*; D009857:Oncogenes; D011519:Proto-Oncogenes; D012689:Sequence Homology, Nucleic Acid
D004274:DNA, Recombinant; D004247:DNA; D004262:DNA Restriction Enzymes