title: Comparative aspects of the production of oxygen radicals by phagocytic cells, and aspects of other effector substances.
abstract: The author reviews the information gleaned from a great variety of sources on the factors influencing the production of oxygen radicals by phagocytic cells, with reference to inflammation. He emphasizes the value of comparative studies, mentioning particularly the effect of leukocyte perturbants, fatty acids and somnogenic leukocyte modulators.
mesh_terms: D000119:Acetylmuramyl-Alanyl-Isoglutamine / Q000031:analogs & derivatives / Q000494:pharmacology; D000818:Animals; D003902:Detergents / Q000494:pharmacology; D005231:Fatty Acids, Unsaturated / Q000494:pharmacology; D006098:Granulocytes / Q000378:metabolism; D006168:Guinea Pigs; D006801:Humans; D006861:Hydrogen Peroxide / Q000378:metabolism; D007962:Leukocytes / Q000378:metabolism; D008051:Lipid Bilayers / Q000378:metabolism; D008264:Macrophages / Q000378:metabolism; D051379:Mice; D010088:Oxidoreductases / Q000378:metabolism; D010100:Oxygen / Q000378:metabolism*; D010586:Phagocytes / Q000378:metabolism*; D010587:Phagocytosis; D012890:Sleep; D013268:Stimulation, Chemical; D013481:Superoxides / Q000378:metabolism; D013501:Surface-Active Agents / Q000494:pharmacology; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology
chemical_list: D003902:Detergents; D005231:Fatty Acids, Unsaturated; D008051:Lipid Bilayers; D013501:Surface-Active Agents; D013481:Superoxides; D000119:Acetylmuramyl-Alanyl-Isoglutamine; D006861:Hydrogen Peroxide; D010088:Oxidoreductases; D013755:Tetradecanoylphorbol Acetate; D010100:Oxygen