Monoclonal antibodies specific for v-abl- and c-abl-encoded molecules.
Monoclonal antibodies specific for regions of the transforming protein of Abelson murine leukemia virus were prepared. Antibodies directed against the kinase domain inhibited the autophosphorylation of v-abl proteins, and all of the antibodies reacted with the products of the murine and human c-abl loci.
D000011:Abelson murine leukemia virus / Q000235:genetics*; D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D009052:Leukemia Virus, Murine / Q000235:genetics*; D051379:Mice; D008807:Mice, Inbred BALB C; D015688:Oncogene Protein pp60(v-src); D009856:Oncogene Proteins, Viral / Q000276:immunology* / Q000378:metabolism; D010766:Phosphorylation; D011494:Protein Kinases / Q000276:immunology; D011817:Rabbits; D012191:Retroviridae Proteins / Q000032:analysis
D000911:Antibodies, Monoclonal; D009856:Oncogene Proteins, Viral; D012191:Retroviridae Proteins; D011494:Protein Kinases; D015688:Oncogene Protein pp60(v-src)