title: [Recent diagnostic methods in herpes simplex].
abstract: Monoclonal antibodies do not only allow a rapid identification of herpes simplex viruses (HSV) on smear specimens, but also a differentiation between HSV type 1 and type 2. Their specificity and sensitivity correspond to conventional molecular biologic methods. Newer insights into epidemiology and recurrency mechanisms are gained by restriction enzyme analysis of the viral genome, which allows accurate determination of types and strains. Finally, hybridization techniques are utilized for further investigations concerning the latency and oncogenic potency of HSV. Thus the spectrum of diagnostic possibilities of HSV infections has considerably been broadened during recent years.
mesh_terms: D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral / Q000032:analysis; D004279:DNA, Viral / Q000235:genetics; D005814:Genes, Viral; D006023:Glycoproteins / Q000032:analysis; D006561:Herpes Simplex / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D007181:Inclusion Bodies, Viral / Q000648:ultrastructure; D008854:Microscopy, Electron; D009693:Nucleic Acid Hybridization; D012367:RNA, Viral / Q000235:genetics; D011863:Radioimmunoassay / Q000379:methods; D012698:Serologic Tests / Q000379:methods; D012703:Serotyping / Q000379:methods; D018139:Simplexvirus / Q000145:classification / Q000276:immunology / Q000302:isolation & purification; D014764:Viral Proteins / Q000032:analysis
chemical_list: D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D004279:DNA, Viral; D006023:Glycoproteins; D007075:Immunoglobulin M; D012367:RNA, Viral; D014764:Viral Proteins
vernacular_title: Neuere diagnostische Methoden beim Herpes simplex.