Representation of amplitude modulation in the auditory cortex of the cat. I. The anterior auditory field (AAF).
The ability of cortical neurons to follow amplitude modulation (AM) of tones was examined in the anterior auditory cortical field (AAF) of anesthetized cats using multiple-unit recording techniques. Sinusoidal and rectangular modulations (100%) of a monaural carrier tone at the characteristic frequency of each location were presented to study the degree of response synchronization and changes in firing rate as a function of the modulation frequency. All investigated locations were tuned to a 'best modulation frequency' (BMF) as determined by synchronization measures. Almost all locations (94%) were tuned to a BMF as determined by spike rate. Maximal binaural-interaction strength was observed for modulation frequencies close to the BMF of neurons. For sinusoidal AM, a correlation (r = 0.63, P less than 0.01) between BMF and CF of neurons in AAF could be demonstrated for the synchronization of the response.
D000161:Acoustic Stimulation; D000818:Animals; D001303:Auditory Cortex / Q000502:physiology*; D001306:Auditory Pathways / Q000502:physiology; D001309:Auditory Threshold / Q000502:physiology; D001931:Brain Mapping; D002415:Cats; D003344:Cortical Synchronization; D005072:Evoked Potentials, Auditory; D009433:Neural Inhibition; D009474:Neurons / Q000502:physiology; D010898:Pitch Perception / Q000502:physiology*; D009435:Synaptic Transmission; D000159:Vestibulocochlear Nerve / Q000502:physiology*