The effect of root detoxification on human gingival fibroblasts.
Comparative growth or inhibition of growth of human gingival fibroblasts on experimental root surfaces was used to assess the efficacy in vitro of the Cavitron and Prophy-Jet. Six teeth with a hopeless periodontal prognosis, slated for prosthetic replacement, were extracted and sectioned into 12 specimens. Experimental specimens were instrumented with the Cavitron or Cavitron and Prophy-Jet. Four calculus-covered control specimens were not treated. Eight root specimens in fibroblast tissue culture were stained with 1.0% toluidine blue for determination of fibroblast viability after 48 hours. No fibroblast growth took place on calculus control specimens. Cavitron specimens showed light fibroblast growth and viability. Cavitron/Prophy-Jet specimens showed superior growth and vitality of fibroblasts.
D000268:Adhesiveness; D001639:Bicarbonates / Q000008:administration & dosage; D002130:Calcium Phosphates / Q000008:administration & dosage; D002478:Cells, Cultured; D003777:Dental Prophylaxis / Q000295:instrumentation*; D004867:Equipment Design; D005347:Fibroblasts / Q000502:physiology*; D005881:Gingiva / Q000166:cytology*; D006801:Humans; D012964:Sodium / Q000008:administration & dosage; D017693:Sodium Bicarbonate; D013997:Time Factors; D014092:Tooth Root / Q000502:physiology*; D014464:Ultrasonic Therapy / Q000295:instrumentation
D001639:Bicarbonates; D002130:Calcium Phosphates; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; D017693:Sodium Bicarbonate; C020243:calcium phosphate; D012964:Sodium; C485829:calcium phosphate, dibasic, anhydrous