[Dendritic action potentials of pyramidal neurons of the sensomotor cortex of the cerebral cortex of the cat].
The intracellular activity of pyramidal tract neurons during electrical stimulation of ventro-lateral and ventro-postero-lateral nuclei of thalamus was studied in acute experiments on cats immobilized by myorelaxants. Both somatic and presumably dendritic spikes (d-spikes) were observed. The latter were characterized by relatively low and variable (5-60 mV) amplitude; d-spikes occurred both spontaneously and in response to single shock and tetanic (8-14/s) stimulation of the thalamus. They were also induced by intracellular depolarizing current pulses and thalamic stimulation following iontophoretic application of strychnine. Simultaneously generated somatic and d-spikes revealed no collision between each other. Intracellular hyperpolarizing current pulses abolished only somatic spikes, while d-spikes were not affected. Dendritic origin with multiple generation zones of these variable spikes is suggested. Possible functional role of d-spike is discussed.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D002415:Cats; D003712:Dendrites / Q000502:physiology; D005071:Evoked Potentials / Q000187:drug effects; D009044:Motor Cortex / Q000502:physiology*; D011712:Pyramidal Tracts / Q000502:physiology*; D013003:Somatosensory Cortex / Q000502:physiology*; D013331:Strychnine / Q000494:pharmacology; D013569:Synapses / Q000502:physiology; D009435:Synaptic Transmission / Q000187:drug effects; D013787:Thalamic Nuclei / Q000502:physiology*
D013331:Strychnine
Dendritnye potentsialy deĭstviia piramidnykh neĭronov sensomotornoĭ kory bol'shikh polushariĭ koshki.