Functional response of the hyperthyroid patients with beta adrenoreceptor blockade to exercise.
The submaximal test of triangular type was used for studying the adaptability to exercise, on an ergometric bicycle. It was performed, starting from O W, with progressive increasing load of 10 W/min until the maximum optimum heart rate (fho) was reached. The heart rate, arterial blood pressure, electrocardiogram, CO2 output and O2 consumption. Computed O2 consumption (VO2 max, ml/kg/min, Astrand) were determined, also taking into account the subjective sensation linked to exercise, measured on a modified Borg scale. The adaptability capacity to exercise was expressed by the adaptability coefficient (AC), according to the formula: AC = W'/2 + (W'-f'). 20 hyperthyroid patients, without cardiothyreosis were examined, both before the uptake of propranolol and after, at a certain interval of time. A decrease of the exercise capacity before the treatment and its increase after it, was noticed in the hyperthyroid patients.
D000222:Adaptation, Physiological / Q000187:drug effects; D000328:Adult; D005080:Exercise Test; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000188:drug therapy / Q000503:physiopathology*; D008297:Male; D005082:Physical Exertion / Q000187:drug effects*; D011433:Propranolol / Q000627:therapeutic use; D011943:Receptors, Adrenergic, beta / Q000187:drug effects*
D011943:Receptors, Adrenergic, beta; D011433:Propranolol