Mapping of haploid expressed genes: genes for both mouse protamines are located on chromosome 16.
Mouse spermatozoa contain two protamines with different amino acid sequences. By hybridizing Southern blots of a series of mouse-hamster somatic cell hybrids containing subsets of mouse chromosomes and a complete set of hamster chromosomes with 32P-labeled cDNAs for each mouse protamine, we assign the two mouse protamine genes to chromosome 16. This report presents the first evidence for chromosomal linkage of two sperm-specific, haploid regulated gene products.
D000818:Animals; D005075:Biological Evolution; D002460:Cell Line; D002874:Chromosome Mapping; D006224:Cricetinae; D003412:Cricetulus; D004262:DNA Restriction Enzymes; D005796:Genes; D006238:Haploidy; D006801:Humans; D006822:Hybrid Cells / Q000166:cytology; D008099:Liver / Q000378:metabolism; D008297:Male; D009693:Nucleic Acid Hybridization; D011479:Protamines / Q000235:genetics*; D013094:Spermatozoa / Q000378:metabolism
D011479:Protamines; D004262:DNA Restriction Enzymes