title: Acquired immune deficiency syndrome (AIDS).
abstract: The epidemiology, clinical and pathologic manifestations, identification of groups at high risk, results of laboratory analyses, and description of the modes of transmission of the putative etiologic agent HTLV-III/LAV have been summarized. Mechanisms of induction of T-cellular immunodeficiency have been described, including the role of HTLV-III/LAV, and possible roles of CMV and EBV as cofactors have been presented. Prospects for preventing and treating AIDS have been succinctly summarized.
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D002648:Child; D017977:Deltaretrovirus / Q000276:immunology; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D007107:Immune System / Q000503:physiopathology; D008221:Lymphoid Tissue / Q000473:pathology; D008297:Male; D009369:Neoplasms / Q000150:complications; D012306:Risk
chemical_list: D000914:Antibodies, Viral