title: [Electron microscopic research in non-A, non-B viral hepatitis with a fecal-oral mechanism of infection transmission].
abstract: Fecal specimens collected in the early stage of the disease from hepatitis patients classified by serological, clinical, and epidemiological data as non-A-non-B hepatitis were examined by means of cross immune electron microscopy. Extracts of feces from such patients were found to contain full, semi-empty, and empty virus particles without envelopes, 27-30 nm in size, forming immune complexes only in the presence of acute and convalescent sera from patients with this type of hepatitis. The lack of serological crosses with hepatitis A and non-A-non-B viruses isolated in other regions suggests that this virus is antigenically distinct. The final solution requires further studies in which methods of molecular biology of viruses should be used.
mesh_terms: D000956:Antigens, Viral / Q000032:analysis; D003289:Convalescence; D003429:Cross Reactions; D005243:Feces / Q000382:microbiology*; D006508:Hepatitis Antibodies / Q000032:analysis; D006510:Hepatitis B Antibodies / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006526:Hepatitis C / Q000276:immunology / Q000382:microbiology / Q000635:transmission*; D006525:Hepatitis, Viral, Human / Q000635:transmission*; D006507:Hepatovirus / Q000276:immunology; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D008854:Microscopy, Electron; D013997:Time Factors; D014771:Virion / Q000276:immunology
chemical_list: D000956:Antigens, Viral; D006508:Hepatitis Antibodies; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D007075:Immunoglobulin M
vernacular_title: Elektronno-mikroskopicheskie issledovaniia pri virusnom gepatite ni A ni B s fekal'no-oral'nym mekhanizmom peredachi infektsii.