title: [Combined therapy of tumors in adults].
abstract: A significant amelioration of treatment results is achieved by sequential chemotherapy and radiotherapy in patients with lymphogranulomatosis of stage IIb to IVb and in patients with non-Hodgkin's lymphomas in corresponding stages. Similar results will probably be obtained in patients with small cell bronchial carcinomas in a limited stage. Patients suffering from an initially inoperable ovarian cancer often reach an operable condition by sequential chemotherapy and radiotherapy. In the stages Dukes B2 and C of the rectum carcinoma, preoperative and/or postoperative irradiation significantly reduces the recurrence rates and increases the survival times. A considerable reduction of recurrence rates is obtained by postoperative radiotherapy in soft tissue sarcomas of the stages T1 to T3. Another improvement is anticipated by a neutron or neutron boost irradiation for stage T3 and by adjuvant chemotherapy for G3 tumors. In the osteosarcoma of adult persons, the results of the limb-sparing sequential therapy will not be worse than the results achieved by amputation. Retrospective analyses of the long-term results of radical mastectomy and conservative operation with postoperative irradiation in case of mammary carcinoma did not show any difference for the stages T1 to T3, N0 to N1.
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000628:therapy; D002283:Carcinoma, Bronchogenic / Q000628:therapy; D018288:Carcinoma, Small Cell / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D006258:Head and Neck Neoplasms / Q000628:therapy; D006689:Hodgkin Disease / Q000628:therapy; D006801:Humans; D008175:Lung Neoplasms / Q000628:therapy; D008223:Lymphoma / Q000628:therapy; D008297:Male; D009369:Neoplasms / Q000628:therapy*; D010051:Ovarian Neoplasms / Q000628:therapy; D012004:Rectal Neoplasms / Q000628:therapy; D012509:Sarcoma / Q000628:therapy; D012983:Soft Tissue Neoplasms / Q000628:therapy; D013274:Stomach Neoplasms / Q000628:therapy; D013736:Testicular Neoplasms / Q000628:therapy; D001749:Urinary Bladder Neoplasms / Q000628:therapy
vernacular_title: Kombinierte Therapie bei Tumoren des Erwachsenen.