title: Functional response of the hyperthyroid patients with beta adrenoreceptor blockade to exercise.
abstract: The submaximal test of triangular type was used for studying the adaptability to exercise, on an ergometric bicycle. It was performed, starting from O W, with progressive increasing load of 10 W/min until the maximum optimum heart rate (fho) was reached. The heart rate, arterial blood pressure, electrocardiogram, CO2 output and O2 consumption. Computed O2 consumption (VO2 max, ml/kg/min, Astrand) were determined, also taking into account the subjective sensation linked to exercise, measured on a modified Borg scale. The adaptability capacity to exercise was expressed by the adaptability coefficient (AC), according to the formula: AC = W'/2 + (W'-f'). 20 hyperthyroid patients, without cardiothyreosis were examined, both before the uptake of propranolol and after, at a certain interval of time. A decrease of the exercise capacity before the treatment and its increase after it, was noticed in the hyperthyroid patients.
mesh_terms: D000222:Adaptation, Physiological / Q000187:drug effects; D000328:Adult; D005080:Exercise Test; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000188:drug therapy / Q000503:physiopathology*; D008297:Male; D005082:Physical Exertion / Q000187:drug effects*; D011433:Propranolol / Q000627:therapeutic use; D011943:Receptors, Adrenergic, beta / Q000187:drug effects*
chemical_list: D011943:Receptors, Adrenergic, beta; D011433:Propranolol