[Metastasizing soft tissue tumor of light damaged skin: atypical fibroxanthoma or malignant fibrous histiocytoma?].
A 86-year-old female patient presented with a ca. walnut-sized, centrally ulcerated preauricular tumor on the right side as well as a firm submandibular lymph node. Histology disclosed a soft-tissue tumor breaking into the lymph node consisting partly of fibroblast-like and partly of histiocyte-like cells. Clinical and histological criteria speak for both an atypical fibroxanthoma (AFX) as well as a malignant fibrous histiocytoma (MFH). A differentiation into two entities does not appear appropriate in our opinion. As the term "AFX" is classified as a benign tumor, "metastasizing AFX" (mAFX) should be considered a special form of MFH or be diagnosed as such, respectively.
D000368:Aged; D003937:Diagnosis, Differential; D005153:Facial Neoplasms / Q000473:pathology*; D005260:Female; D005354:Fibrosarcoma / Q000473:pathology*; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology*; D006801:Humans; D008854:Microscopy, Electron; D009381:Neoplasms, Radiation-Induced / Q000473:pathology*; D012867:Skin / Q000473:pathology
Metastasierender Weichgewebstumor lichtgeschädigter Haut: Atypisches Fibroxanthom oder malignes fibröses Histiozytom?