title: Electron microscopic detection of virus particles in the rhino mouse.
abstract: The rhino mouse, an experimental model for systemic lupus erythematosus, was found to have murine leukemia virus particles present in the skin. Immunoperoxidase studies with anti-type C virus antibody indicated viral antigen presence in the sebaceous cells and surrounding follicular cysts of the dermis. Electron microscope studies show virus particles, both type C extracellularly and type A intracellularly, around follicular cysts. Virus particle was labeled with specific ferritin-conjugated antitype C virus antibody.
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D006720:Homozygote; D007124:Immunoenzyme Techniques; D009052:Leukemia Virus, Murine / Q000302:isolation & purification*; D008180:Lupus Erythematosus, Systemic / Q000235:genetics / Q000662:veterinary; D051379:Mice; D008817:Mice, Mutant Strains / Q000382:microbiology*; D008854:Microscopy, Electron; D012867:Skin / Q000382:microbiology; D014771:Virion / Q000302:isolation & purification*