Biologic interaction of prostaglandin, thromboxane and prostacyclin: potential clinical applications.
Prostaglandins are vasoactive agents which have potent and varied effects depending on the species, conditions and organs tested. The clinician wishing to gain a significant overview of the field from current research literature has a demanding task for himself. A review of biologic interactions is exactly what is needed in a consideration of possible clinical applications of prostaglandins. Thus, it is necessary first to recount the last five years' advances in prostaglandin research. Only then will the listing and discussion of some diseases soon to benefit from the application of research be meaningful.
D000818:Animals; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000378:metabolism; D001241:Aspirin / Q000627:therapeutic use; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism; D000242:Cyclic AMP / Q000032:analysis; D016861:Cyclooxygenase Inhibitors; D011464:Epoprostenol / Q000502:physiology*; D006801:Humans; D010974:Platelet Aggregation / Q000187:drug effects; D011448:Prostaglandin Antagonists / Q000627:therapeutic use; D011453:Prostaglandins / Q000502:physiology*; D009626:Terminology as Topic; D013931:Thromboxanes / Q000037:antagonists & inhibitors / Q000502:physiology*; D014652:Vascular Diseases / Q000188:drug therapy / Q000209:etiology
D001095:Arachidonic Acids; D016861:Cyclooxygenase Inhibitors; D011448:Prostaglandin Antagonists; D011453:Prostaglandins; D013931:Thromboxanes; D016718:Arachidonic Acid; D011464:Epoprostenol; D000242:Cyclic AMP; D001241:Aspirin