title: Structure of the Epstein-Barr virus nuclear antigen as probed with monoclonal antibodies.
abstract: Five hybridoma cell lines secreting antibodies directed against an Epstein-Barr virus (EBV) nuclear antigen (BamHI K antigen) have been isolated. All five antibodies detect this antigen in a variety of EBV-positive lymphoblastoid cell lines. The reaction of these antibodies with several mutant forms of this protein has allowed the antibody binding site(s) to be predicted.
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal; D000956:Antigens, Viral / Q000032:analysis* / Q000235:genetics; D002460:Cell Line; D002478:Cells, Cultured; D004262:DNA Restriction Enzymes; D015245:Deoxyribonuclease BamHI; D019309:Epstein-Barr Virus Nuclear Antigens; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000276:immunology*; D006825:Hybridomas / Q000276:immunology; D051379:Mice; D008970:Molecular Weight
chemical_list: D000911:Antibodies, Monoclonal; D000956:Antigens, Viral; D019309:Epstein-Barr Virus Nuclear Antigens; D004262:DNA Restriction Enzymes; D015245:Deoxyribonuclease BamHI