title: [Isoenzymes of blast cells in malignant hemopathies: present state and prospectives].
abstract: Numerous isoenzymes are used as markers in the course of malignant haemopathies. These are notably the isoenzymes of lactic dehydrogenase, hexosaminidase, esterases, acid phosphatases, and thymidine kinase. Their study already permits a finer and more rigorous classification of leukaemias and makes it possible to entertain serious hopes in at least three spheres: a better choice of treatment, surveillance of therapeutic efficacy and of remissions, and the development of new modes of therapeutic action by means of selective inhibitors.
mesh_terms: D000118:Acetylglucosaminidase / Q000097:blood; D000135:Acid Phosphatase / Q000097:blood; D000243:Adenosine Deaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D000626:Aminopeptidases / Q000097:blood; D001402:B-Lymphocytes / Q000201:enzymology; D002051:Burkitt Lymphoma / Q000201:enzymology; D002454:Cell Differentiation; D000242:Cyclic AMP / Q000494:pharmacology; D004950:Esterases / Q000097:blood; D006593:Hexokinase / Q000097:blood; D006596:Hexosaminidases / Q000097:blood; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D007770:L-Lactate Dehydrogenase / Q000097:blood; D007938:Leukemia / Q000145:classification / Q000201:enzymology*; D007945:Leukemia, Lymphoid / Q000201:enzymology; D007948:Leukemia, Monocytic, Acute / Q000201:enzymology; D008247:Lysosomes / Q000201:enzymology; D008361:Mannosidases / Q000097:blood; D010732:Phosphofructokinase-1 / Q000097:blood; D011494:Protein Kinases / Q000097:blood; D011683:Purine-Nucleoside Phosphorylase / Q000097:blood; D011770:Pyruvate Kinase / Q000097:blood; D012268:Ribose-Phosphate Pyrophosphokinase / Q000097:blood; D013601:T-Lymphocytes / Q000201:enzymology; D013937:Thymidine Kinase / Q000097:blood; D000519:alpha-Galactosidase / Q000097:blood; D043323:alpha-Mannosidase
chemical_list: D007527:Isoenzymes; D000242:Cyclic AMP; D007770:L-Lactate Dehydrogenase; D011683:Purine-Nucleoside Phosphorylase; D011494:Protein Kinases; D006593:Hexokinase; D010732:Phosphofructokinase-1; D013937:Thymidine Kinase; D011770:Pyruvate Kinase; D012268:Ribose-Phosphate Pyrophosphokinase; D004950:Esterases; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D006596:Hexosaminidases; D008361:Mannosidases; D000519:alpha-Galactosidase; D043323:alpha-Mannosidase; D000118:Acetylglucosaminidase; D000626:Aminopeptidases; D000243:Adenosine Deaminase
vernacular_title: Isoenzymes des cellules blastiques au cours des hémopathies malignes: actualité et prospective.