title: [Characteristics of the derepressed mutant of the F-like plasmid pAP18-1 coding for tetracycline resistance in Escherichia coli].
abstract: A transfer function derepressed mutant of the F-like plasmid pAP18-1 (Tc, ColV) was induced with the help of N-methyl-N'-nitro-N-nitrozoguanidine. The mutant plasmid pAP18-1drd belongs to the FVII incompatibility group of the F-like plasmids. The plasmid pAP18-1drd is characterized by the loss of the capacity for inhibiting the tra-genes functions of the Flac plasmid and is sensitive to the Tra-function inhibitors of the reference plasmids of the FinV and FinW groups.
mesh_terms: D003227:Conjugation, Genetic / Q000187:drug effects; D004251:DNA Transposable Elements / Q000187:drug effects; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics*; D005144:F Factor / Q000187:drug effects; D005786:Gene Expression Regulation / Q000187:drug effects; D005798:Genes, Bacterial / Q000187:drug effects; D005815:Genetic Code / Q000187:drug effects; D008769:Methylnitronitrosoguanidine / Q000494:pharmacology; D009154:Mutation; D013752:Tetracycline / Q000037:antagonists & inhibitors*
chemical_list: D004251:DNA Transposable Elements; D008769:Methylnitronitrosoguanidine; D013752:Tetracycline
vernacular_title: Kharakteristika derepressirovannogo mutanta F-podobnoĭ plazmidy pAP18-1, kodiruiushcheĭ rezistentnost' k tetratsiklinu u Escherichia coli.