[Germ cell tumor of the testis--clinicopathologic analysis of 114 cases].
The histologic features and clinical records of 114 cases of germ cell tumors of the testis proved by pathology in our hospital from 1951 to 1980 are reviewed. These cases were divided into six types: seminoma 49.1%, embryonal carcinoma 8.8%, yolk sac tumor 17.5%, choriocarcinoma 0.9%, teratoma 14.9% and mixed carcinoma 8.8%. The over-all incidence of metastasis observed on exploration was 41.2%, and in embryonal and mixed carcinoma it was the highest, each amounting to 80%. Site of metastasis was: inguinal and retroperitoneal lymph nodes 63.8%, mesenteric lymph nodes 6.4%, liver 12.8%, lung 8.5% and supraclavicular lymph nodes 8.5%. In the 24 followed cases, 13 were seminomas and 11 non-seminomatous germ cell tumors. 5 of the former and 9 of the latter died of the tumor. It is advised that, in addition to radical orchiectomy, supplementary radiotherapy to the original site in the testis and the retroperitoneal draining lymphatics be given to seminoma and retroperitoneal lymph node dissection be given to non-seminomatous germ cell tumors except the pure choriocarcinoma to improve the result.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D004407:Dysgerminoma / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D008649:Mesonephroma / Q000473:pathology; D008875:Middle Aged; D009373:Neoplasms, Germ Cell and Embryonal / Q000473:pathology*; D013724:Teratoma / Q000473:pathology; D013736:Testicular Neoplasms / Q000473:pathology*