Distinctive eruption characterized by linear supravenous papules and erythroderma following broxuridine (bromodeoxyuridine) therapy and radiotherapy.
A distinctive cutaneous eruption occurred in two patients with central nervous system tumors who were treated with broxuridine (bromodeoxyuridine) and radiotherapy. Findings included the initial appearance of papular lesions within skin directly overlying acral superficial veins and the later development of a more generalized eruption eventuating into exfoliative erythroderma.
D001932:Brain Neoplasms / Q000532:radiotherapy*; D001973:Bromodeoxyuridine / Q000009:adverse effects*; D003873:Dermatitis, Exfoliative / Q000139:chemically induced* / Q000473:pathology; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D005909:Glioblastoma / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011838:Radiation-Sensitizing Agents / Q000009:adverse effects*; D012867:Skin / Q000473:pathology*
D011838:Radiation-Sensitizing Agents; D001973:Bromodeoxyuridine