T1 and T2 proton nuclear magnetic resonance (N.M.R.) relaxation times in vitro and human intracranial tumours. Results from 98 patients.
137 samples of intracranial tumours have been studied in proton NMR spectroscopy. T1 and T2 relaxation times are above those of normal grey and white matter. Differential diagnosis between benign and malignant brain tumours does not seem feasible upon proton T1 and T2 alone. Histological correlations allowed us to specify secondary changes accounting for T1 and T2 variations (oedema, microcyst, stroma reaction, necrosis).
D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology*; D003094:Collagen / Q000032:analysis; D003937:Diagnosis, Differential; D004487:Edema / Q000473:pathology; D005910:Glioma / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008527:Medulloblastoma / Q000175:diagnosis / Q000473:pathology; D008579:Meningioma / Q000175:diagnosis / Q000473:pathology; D008938:Mitosis; D009336:Necrosis; D011522:Protons
D011522:Protons; D003094:Collagen