Proton and potassium fluxes in rat red blood cells incubated with sugar phosphates.
Fructose-1,6-diphosphate counteracts potassium ejection and proton uptake induced in rat red blood cells by valinomycin and an uncoupler. The effect on potassium ejection is reduced in the presence of ouabain and divalent cations.
D000818:Animals; D002118:Calcium / Q000494:pharmacology; D002259:Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone / Q000494:pharmacology; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism*; D005635:Fructosediphosphates / Q000494:pharmacology*; D006598:Hexosediphosphates / Q000494:pharmacology*; D008274:Magnesium / Q000494:pharmacology; D008297:Male; D010042:Ouabain / Q000494:pharmacology; D011188:Potassium / Q000097:blood*; D011522:Protons; D051381:Rats; D011919:Rats, Inbred Strains; D014634:Valinomycin / Q000494:pharmacology
D005635:Fructosediphosphates; D006598:Hexosediphosphates; D011522:Protons; D014634:Valinomycin; D002259:Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; D010042:Ouabain; C027652:fructose 2,6-diphosphate; D008274:Magnesium; C029063:fructose-1,6-diphosphate; D011188:Potassium; D002118:Calcium