Arthritis associated with crystals containing calcium.
Varying combinations of acute inflammatory and/or chronic degenerative arthritis have been found to be associated with crystals of calcium pyrophosphate dihydrate (CPPD) and/or basic calcium phosphates (BCPs). Since the arthropathies associated with CPPDs and/or BCPs occur in older individuals, while diagnosis and treatment for monosodium urate monohydrate crystal deposition disease (gout) have become extremely precise and effective, joint problems associated with calcium crystals have become more common than those associated with monosodium urate monohydrate crystals. The classification, pathogenesis, clinical manifestations, and treatment of CPPD and BCP crystal deposition are discussed.
D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001168:Arthritis / Q000378:metabolism*; D002130:Calcium Phosphates / Q000032:analysis / Q000378:metabolism*; D002131:Calcium Pyrophosphate / Q000032:analysis / Q000378:metabolism*; D003078:Colchicine / Q000627:therapeutic use; D003460:Crystallization; D011756:Diphosphates / Q000378:metabolism*; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007249:Inflammation / Q000139:chemically induced; D007592:Joint Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology / Q000378:metabolism; D008722:Methods; D010447:Peptide Hydrolases / Q000378:metabolism; D011859:Radiography; D012785:Shoulder Joint; D013577:Syndrome; D013583:Synovial Membrane / Q000473:pathology
D000893:Anti-Inflammatory Agents; D002130:Calcium Phosphates; D011756:Diphosphates; D010447:Peptide Hydrolases; D003078:Colchicine; D002131:Calcium Pyrophosphate