Leukocytes and tissue injury: the use of eicosapentaenoic acid in the control of white cell activation.
Eicosapentaenoic acid enriched diet may reduce the severity of acute inflammatory reactions by decreasing the synthesis of dienoic prostanoids and tetraenoic leukotrienes. The findings suggest that a nutritional approach to anti-inflammatory therapy is an interesting possibility deserving further studies.
D000818:Animals; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000378:metabolism; D015118:Eicosapentaenoic Acid / Q000494:pharmacology*; D007249:Inflammation / Q000276:immunology*; D007962:Leukocytes / Q000187:drug effects* / Q000276:immunology; D007975:Leukotriene B4 / Q000378:metabolism; D051381:Rats; D013189:SRS-A / Q000378:metabolism
D001095:Arachidonic Acids; D013189:SRS-A; D007975:Leukotriene B4; D016718:Arachidonic Acid; D015118:Eicosapentaenoic Acid