Active immunization of children exposed to varicella infection in a hospital ward using live attenuated varicella vaccine given subcutaneously or intracutaneously.
Active immunization using Takahashi OKA live attenuated varicella vaccine was carried out fire 5 times to prevent the spread of "imported" varicella in a hospital ward. Susceptibility was previously tested by serological examinations: 14 children were vaccinated subcutaneously, the other 19 received the vaccine intracutaneously. Vaccination within a few days following exposure provided complete immunity in the great majority of cases. Intracutaneous administration was nearly as protective as the subcutaneous one.
D002644:Chickenpox / Q000517:prevention & control*; D019433:Chickenpox Vaccine; D002648:Child; D002675:Child, Preschool; D003428:Cross Infection / Q000517:prevention & control*; D014645:Herpesvirus 3, Human; D006801:Humans; D007223:Infant; D008722:Methods; D014611:Vaccination; D014765:Viral Vaccines / Q000008:administration & dosage*
D019433:Chickenpox Vaccine; D014765:Viral Vaccines