title: [Stimulation of mitochondrial oxidative enzymes in acute cooling and its catecholamine mechanisms].
abstract: Acute cooling of rats led to stimulation of NAD+-dependent isocitrate dehydrogenase (ICDH), succinate dehydrogenase (SDH) and NAD(P)+-transhydrogenase (TH) but did not affect the NADP+-ICDH activity in liver, heart and skeletal muscle mitochondria. After pretreatment of the animals with propranolol the stimulating effect was decreased, thus suggesting that endogenous catecholamines and beta-adrenoreceptors are of importance in activation of NAD+-ICDH, SDH and TH. The effects of cooling, noradrenaline and cAMP did not summarize. Role of catecholamines in stimulation of mitochondrial oxidative enzymes under conditions of cooling is discussed.
mesh_terms: D000818:Animals; D002395:Catecholamines / Q000502:physiology*; D003080:Cold Temperature; D004789:Enzyme Activation; D008929:Mitochondria, Heart / Q000201:enzymology*; D008930:Mitochondria, Liver / Q000201:enzymology*; D010105:Oxygenases / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D011943:Receptors, Adrenergic, beta / Q000187:drug effects; D013312:Stress, Physiological / Q000201:enzymology* / Q000503:physiopathology
chemical_list: D002395:Catecholamines; D011943:Receptors, Adrenergic, beta; D010105:Oxygenases
vernacular_title: Stimuliatsiia okislitel'nykh fermentov mitokhondriĭ pri ostrom okhlazhdenii i ee katekholaminovye mekhanizmy.