[Effect of chronic psychogenic stress on a number of behavioral and neurochemical characteristics of rats].
Fifteen-day chronic stress with randomized footshock reinforcement (group 4) causes profound steady disturbances in the animal behavior. With the use of regular aversive reinforcement in the shuttle-box the rats were divided into two groups: "escaping" (group 2) and "non-escaping" (group 3). Minor behavioral disturbances were observed in group 2, moderate in group 3 and maximum in group 4. In the latter group "down-regulation" of beta-adrenoceptors and benzodiazepine receptors was observed. The receptor changes appear to be rather the result of psychogenic factors caused by randomized reinforcement than of physical stress as such.
D000818:Animals; D001362:Avoidance Learning; D001835:Body Weight; D001921:Brain / Q000378:metabolism*; D004082:Dihydroalprenolol / Q000378:metabolism; D005445:Flunitrazepam / Q000378:metabolism; D008297:Male; D008566:Membranes / Q000378:metabolism; D009043:Motor Activity; D051381:Rats; D011943:Receptors, Adrenergic, beta / Q000378:metabolism; D013315:Stress, Psychological / Q000378:metabolism / Q000503:physiopathology*
D011943:Receptors, Adrenergic, beta; D004082:Dihydroalprenolol; D005445:Flunitrazepam
Vliianie khronicheskogo psikhogennogo stressa na riad povedencheskikh i neĭrokhimicheskikh kharakteristik krys.