Sequences in the proximal IRL of herpes simplex virus DNA hybridize to human DNA.
A short segment of the herpes simplex virus (HSV) DNA proximal IRL region hybridized to two doublet bands of EcoRI-digested human cellular DNA. The hybridization was abolished neither by increasing stringency conditions nor by inclusion of guanine-rich DNA in the hybridization mixture. Thus, the hybridization appeared to represent authentic base sequence homology between HSV DNA and middle repetitive human DNA.
D004247:DNA; D004262:DNA Restriction Enzymes; D004279:DNA, Viral; D015246:Deoxyribonuclease EcoRI; D006801:Humans; D009693:Nucleic Acid Hybridization; D012689:Sequence Homology, Nucleic Acid; D018139:Simplexvirus / Q000235:genetics*
D004279:DNA, Viral; D004247:DNA; D004262:DNA Restriction Enzymes; D015246:Deoxyribonuclease EcoRI