title: [Histology of the primary tumor and subsequent metastasis in breast cancer].
abstract: The relationship between the histology of the primary tumour and subsequent metastasization was analysed in 343 patients with disseminated carcinoma of the breast. The metastases were subdivided on clinical criteria into osseous, visceral and localized regional ones. It was found that undifferentiated, infiltrating ductal carcinomas without significant productive fibrosis have a special tendency towards visceral metastasization. Purely scirrhous carcinomas, especially without intraductal components, have a marked affinity to the skeletal systems. Intraductally growing and adenomatous carcinomas appear to metastasize ubiquitously. The more components there are to the primary tumour the more frequent are local recurrences and metastases to several organ systems.
mesh_terms: D002293:Adenocarcinoma, Scirrhous / Q000473:pathology; D000236:Adenoma / Q000473:pathology; D001859:Bone Neoplasms / Q000556:secondary; D001943:Breast Neoplasms / Q000473:pathology*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology; D005260:Female; D006801:Humans; D007414:Intestinal Neoplasms / Q000556:secondary; D009362:Neoplasm Metastasis
vernacular_title: Histologie des Primärtumors und nachfolgende Metastasierung beim Mammakarzinom.