Dispersed chromosomal localization of the proto-oncogenes transduced into the genome of Mill Hill 2 or E26 leukemia virus.
Both Mill Hill 2 and E26 retroviruses have transduced two cellular genes--c-myc and c-mil/mht (Mill Hill 2) and c-myb and c-ets (E26). We localized the genes transduced by these viruses to different chromosomes: c-myc and c-myb to relatively large chromosomes and c-mil/mht and c-ets to microchromosomes. Thus, like avian erythroblastosis virus, each of these retroviruses has transduced two cellular genes unlinked in the chicken genome.
D000818:Animals; D001354:Avian Leukosis Virus / Q000235:genetics*; D002645:Chickens / Q000235:genetics / Q000382:microbiology; D002874:Chromosome Mapping; D008040:Genetic Linkage; D009693:Nucleic Acid Hybridization; D011519:Proto-Oncogenes; D014161:Transduction, Genetic