title: Species differences in the angiotensin converting enzyme activity of mammalian serum.
abstract: Angiotensin converting enzyme (ACE; EC 3. 4. 15. 1) activities were compared in the serum of various mammals. Cattle, human, monkey, and swine serum showed enzyme levels from 3.7 to 67 mU/ml. Relatively high enzyme activity was observed in rodents, the rat (Wistar) and mouse (BALB/c) showing levels of 93 +/- 7 and 1052 +/- 165 mU/ml, respectively. Among the mammalian sera examined, that of the guinea pig contained the highest ACE level, 2262 +/- 574 mU/ml. No age-related difference in enzyme activity was observed in 10-day-old to 1-year-old guinea pigs.
mesh_terms: D000328:Adult; D000818:Animals; D002417:Cattle; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D008252:Macaca fascicularis; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008875:Middle Aged; D007703:Peptidyl-Dipeptidase A / Q000097:blood*; D051381:Rats; D011919:Rats, Inbred Strains; D013045:Species Specificity; D013552:Swine
chemical_list: D007703:Peptidyl-Dipeptidase A