Regulation of electron transfer by the quinone pool.
Strong evidence for a random collisional mechanism for ubiquinone-mediated electron transfer is provided by the characteristic kinetic properties of respiratory chains originally explored by Kröger, A., and Klingenberg, M. (1973), Eur. J. Biochem. 34, 313-323. A kinetic model which leads to this so-called "simple Q-pool behavior" has been described and we use this in reviewing evidence that electron transfer is diffusion-controlled as well as diffusion-coupled. We also consider mechanisms by which the kinetics of electron transfer might deviate from simple Q-pool behavior and how these might be implicated in the regulation of electron transport.
D016227:Benzoquinones; D004058:Diffusion; D004579:Electron Transport; D014450:Electron Transport Complex III / Q000378:metabolism; D007700:Kinetics; D008433:Mathematics; D008563:Membrane Lipids / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D016660:NAD(P)H Dehydrogenase (Quinone); D011808:Quinone Reductases / Q000378:metabolism; D011809:Quinones / Q000378:metabolism*; D014451:Ubiquinone / Q000378:metabolism
D016227:Benzoquinones; D008563:Membrane Lipids; D008565:Membrane Proteins; D011809:Quinones; D014451:Ubiquinone; C004532:quinone; D016660:NAD(P)H Dehydrogenase (Quinone); D011808:Quinone Reductases; D014450:Electron Transport Complex III