title: [Effect of thiamine on auditory evoked potentials of the guinea pig].
abstract: Application of thiamine (1 X 10(-11)-1 X 10(-3) mol/l) on the membrane of cochlear round window increased the amplitude and decreased the latency of the auditory nerve action potential, waves I and II of brainstem auditory-evoked electrical potentials in response to acoustic clicks of different intensity. The mechanism of thiamine action on auditory-evoked electric potentials is discussed.
mesh_terms: D000818:Animals; D001933:Brain Stem / Q000502:physiology*; D003051:Cochlea / Q000187:drug effects*; D005072:Evoked Potentials, Auditory / Q000187:drug effects*; D006168:Guinea Pigs; D006198:Hair Cells, Auditory / Q000187:drug effects; D009430:Neural Analyzers / Q000187:drug effects; D011930:Reaction Time / Q000187:drug effects; D012405:Round Window, Ear / Q000187:drug effects*; D013136:Spiral Ganglion / Q000187:drug effects; D009435:Synaptic Transmission / Q000187:drug effects; D013831:Thiamine / Q000494:pharmacology*; D000159:Vestibulocochlear Nerve / Q000502:physiology
chemical_list: D013831:Thiamine
vernacular_title: Deĭstvie tiamina na slukhovye vyzvannye potentsialy u morskoĭ svinki.