The protective effect of pollen extracts against allyl alcohol damage of the liver.
In male Wistar rats the hepatoprotective effect of pollen extracts (Cernitins) agains. orally introduced 1% allyl alcohol (0.4 ml per 100 g body weight) was investigated Cernitins were applied orally at 0.6, 24 and 30 h after allyl alcohol administration. After 48 h an autopsy was performed and blood was collected for biochemical tests. Liver damage was evaluated by measurement of aminotransferases (AspAT, AlAT) and alkaline phosphatase activity, total bilirubin level in the blood serum as well as by histological examination of the livers. Cernitins significantly reduced the serum enzymes elevations induced by allyl alcohol. The hepatoprotective properties of Cernitins were confirmed by histopathological studies.
D000433:1-Propanol / Q000494:pharmacology / Q000633:toxicity; D000818:Animals; D002479:Inclusion Bodies; D008099:Liver / Q000166:cytology / Q000187:drug effects* / Q000201:enzymology / Q000473:pathology; D008297:Male; D009336:Necrosis / Q000517:prevention & control*; D008517:Phytotherapy; D010936:Plant Extracts; D011058:Pollen / Q000008:administration & dosage / Q000494:pharmacology*; D020005:Propanols; D051381:Rats; D011919:Rats, Inbred Strains; D012434:Secale
D010936:Plant Extracts; D020005:Propanols; C006463:allyl alcohol; C010070:cernilton; D000433:1-Propanol