Epstein-Barr virus activation by human semen principle: synergistic effect of culture fluids of bacteria isolated from patients with carcinoma of uterine cervix.
Epstein-Barr virus early antigens (EBV EA) were induced in a Raji cell system in order to assay the activity of the EA inducer in human semen. In semen from 53 Chinese, 45.3% induced EBV EA in Raji cells. Such positive semen and EBV-inducing positive culture fluids of bacteria isolated from the uterine cervix of patients with cervical carcinoma had a synergistic effect on the induction of EBV EA. This synergistic effect as related to the cause of cervical carcinoma is discussed.
D000956:Antigens, Viral / Q000032:analysis; D018407:Bacterial Physiological Phenomena; D003470:Culture Media; D005260:Female; D004854:Herpesvirus 4, Human / Q000254:growth & development* / Q000276:immunology; D006801:Humans; D008297:Male; D012661:Semen / Q000502:physiology*; D002583:Uterine Cervical Neoplasms / Q000209:etiology / Q000382:microbiology*; D014775:Virus Activation
D000956:Antigens, Viral; D003470:Culture Media