Decrease of lymphocyte (Na+,K+)ATP-ase activity in aged people.
Activity of (Na+,K+)ATP-ase measured by means of influx of 86Rb was compared in lymphocytes from young, middle-age and old people. It was found that the (sensitive to ouabain) activity of (Na+,K+)ATPase was significantly diminished in the lymphocytes from aged subjects.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D001693:Biological Transport, Active; D001799:Blood Sedimentation; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000145:classification / Q000201:enzymology*; D008297:Male; D008875:Middle Aged; D011868:Radioisotopes; D012413:Rubidium; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*
D011868:Radioisotopes; D000254:Sodium-Potassium-Exchanging ATPase; D012413:Rubidium