Scintigraphic diagnosis of primary hepatocellular carcinoma in the woodchuck (Marmota monax).
Hepatic imaging with 99mTc-sulfur colloid was used to diagnose primary hepatocellular carcinoma (PHC) in woodchucks infected with woodchuck hepatitis virus (WHV). Based on imaging results, 6 of 12 WHV-infected woodchucks had space-occupying hepatic lesions, and all 6 had PHC. Of the remaining woodchucks, 2 did not have PHC, 2 had discrete tumors (less than 1 cm diameter), 1 had miliary small tumors, and 1 had tumors located near the great vessels. Hepatic imaging was a valuable technique for diagnosis of PHC in WHV-infected woodchucks.
D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D005260:Female; D006514:Hepatitis B Surface Antigens / Q000276:immunology; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D008297:Male; D008392:Marmota / Q000276:immunology; D011877:Radionuclide Imaging; D012589:Sciuridae / Q000276:immunology
D006514:Hepatitis B Surface Antigens