title: Immunologic profiles of cats with persistent, naturally acquired feline leukemia virus infection.
abstract: Several immunologic responses were measured in 13 healthy cats with naturally acquired, persistent feline leukemia virus (FeLV) viremia from 4 multiple-cat households and were compared with responses from 28 of their healthy, non-FeLV-viremic housemates. Significant differences (P = less than 0.05) were not observed between results of FeLV-viremic and nonviremic cats for peripheral blood leukocyte or lymphocyte count, percentage of peripheral blood mononuclear cells able to form rosettes with guinea pig RBC or with antibody- and complement-coated sheep RBC, lymphocyte proliferative response to concanavalin A or pokeweed mitogen, or serum immunoglobulin G concentration. Seemingly, persistent FeLV viremia, when naturally acquired, may exist for some time without lymphopenia or a marked loss of mitogen-induced lymphocyte proliferation.
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000276:immunology* / Q000382:microbiology; D002415:Cats; D005260:Female; D007938:Leukemia / Q000276:immunology / Q000382:microbiology / Q000662:veterinary*; D005256:Leukemia Virus, Feline; D008297:Male