Epoxidation of alkenes by chloroperoxidase catalysis.
Chloroperoxidase from Caldariomyces fumago catalyzes the peroxidation of alkenes to epoxides. This enzyme is the only haloperoxidase of four tested capable of carrying out the reaction. These results further establish chloroperoxidase as a unique haloperoxidase, and adds this enzyme to the short list of other enzymes (e.g., cytochrome P-450) known to epoxidize alkenes.
D000475:Alkenes / Q000378:metabolism*; D002711:Chloride Peroxidase / Q000378:metabolism*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004852:Epoxy Compounds / Q000378:metabolism*; D004988:Ethers, Cyclic / Q000378:metabolism*; D008401:Gas Chromatography-Mass Spectrometry; D006735:Horseradish Peroxidase / Q000378:metabolism; D007784:Lactoperoxidase / Q000378:metabolism; D003904:Mitosporic Fungi / Q000201:enzymology; D009195:Peroxidase / Q000378:metabolism; D010544:Peroxidases / Q000378:metabolism*; D020058:Styrene; D013343:Styrenes / Q000378:metabolism
D000475:Alkenes; D004852:Epoxy Compounds; D004988:Ethers, Cyclic; D013343:Styrenes; D020058:Styrene; D003577:Cytochrome P-450 Enzyme System; D006735:Horseradish Peroxidase; D007784:Lactoperoxidase; D010544:Peroxidases; D002711:Chloride Peroxidase; D009195:Peroxidase