Laryngeal blastoma. A light and electron microscopic study of a novel entity analogous to pulmonary blastoma.
A neoplasm morphologically analogous to pulmonary blastoma, but arising in the pyriform fossa of the larynx, is described and illustrated. The patient, a 65-year-old white man, was treated with laryngectomy and is alive and free of disease 13 months later. Grossly polypoid on a broad stalk, the neoplasm consisted of a mixture of blastematous, mesenchymal, and epithelial elements. Ultrastructural examination showed that the spindle and stellate cells were truly mesenchymal. The name "laryngeal blastoma" is proposed for this novel entity.
D000368:Aged; D004848:Epithelium / Q000473:pathology; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology*; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000473:pathology*