Collagenolytic activity of Coccidioides immitis.
Coccidioides immitis appears to be unable to digest particulate collagen when cultured on collagen-containing semisolid culture media. However, all C. immitis strains solubilized collagen when the fungus was grown in liquid suspension cultures. Moreover, sterile culture filtrates were collagenolytic in collagen-buffer-agar plate assays.
D003045:Coccidioides / Q000201:enzymology*; D003012:Microbial Collagenase / Q000378:metabolism*; D012995:Solubility; D013329:Structure-Activity Relationship; D013379:Substrate Specificity
D003012:Microbial Collagenase