title: Marihuana and driving.
abstract: A review was performed of the marihuana and driving literature, both epidemiological and experimental. It was noted that epidemiological studies face considerable difficulties in obtaining estimates of risks involved for drivers utilizing marihuana due to the rapid decline in blood levels of tetrahydrocannabinol. On the other hand, experimental studies examining the relationship between administered marihuana dose and performance have identified many driving-related areas as exhibiting impairment. Areas impaired include coordination, tracking, perception, vigilance and performance in both driving simulators and on the road. Other behavioral areas of lesser importance for driving also exhibited evidence of impairment by marihuana. Areas for further research are suggested.
mesh_terms: D000063:Accidents, Traffic; D000401:Aircraft; D001334:Automobile Driving; D001634:Bibliographies as Topic; D002188:Cannabis; D013759:Dronabinol / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D004347:Drug Interactions; D000431:Ethanol / Q000097:blood; D005133:Eye Movements / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D010465:Perception / Q000187:drug effects; D011597:Psychomotor Performance / Q000187:drug effects; D011930:Reaction Time / Q000187:drug effects; D012309:Risk-Taking; D012684:Sensory Thresholds / Q000187:drug effects; D012737:Sex Factors; D013997:Time Factors
chemical_list: D000431:Ethanol; D013759:Dronabinol