[Malignant cell transformation in rats in vitro as affected by the variolovaccine virus].
The capacity of the variolovaccine virus with low cytopathogenic activity to cause morphologic and malignant transformation of normal rat cells in vitro is detected. The transformed cells induced tumours in gamma-irradiated rats.
D000818:Animals; D000831:Animals, Newborn; D000956:Antigens, Viral / Q000032:analysis; D002471:Cell Transformation, Neoplastic / Q000276:immunology / Q000473:pathology* / Q000528:radiation effects; D002472:Cell Transformation, Viral / Q000528:radiation effects; D002478:Cells, Cultured; D003043:Cocarcinogenesis; D004622:Embryo, Mammalian; D005720:Gamma Rays; D009368:Neoplasm Transplantation; D051381:Rats; D014466:Ultraviolet Rays; D012901:Variola virus / Q000276:immunology / Q000472:pathogenicity* / Q000528:radiation effects
D000956:Antigens, Viral
Zlokachestvennaia transformatsiia kletok krys in vitro pod vliianiem virusa ospovaktsiny.