Influence of noradrenalin on pterygopalatine ganglionic transmission of the rabbit in vitro.
The influence of noradrenalin on pterygopalatine ganglionic transmission was examined in the rabbit in vitro. Electrical activity recorded from the posterior nasal nerve in response to stimulation of the vidian nerve was reversibly inhibited by the superfusion of noradrenalin. This inhibition was counteracted by phentolamine. This result indicates that, through alpha-adrenergic receptors, noradrenalin inhibits transmission in the pterygopalatine ganglion.
D000818:Animals; D004558:Electric Stimulation; D005726:Ganglia, Parasympathetic / Q000187:drug effects* / Q000502:physiology; D066298:In Vitro Techniques; D008297:Male; D009638:Norepinephrine / Q000494:pharmacology*; D011817:Rabbits; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects / Q000502:physiology; D009435:Synaptic Transmission / Q000187:drug effects*
D011942:Receptors, Adrenergic, alpha; D009638:Norepinephrine