title: [Induction of unstable mutations in Drosophila melanogaster by microinjection of DNA from oncogenic viruses into the embryo polar plasma. I. Effect of the embryo genotype].
abstract: We have studied the spectrum and nature of mutations induced by oncogenic virus DNA injections into wsn, T-007 line of embryos, and those of the first generation hybrids obtained after crossing the T-007 line males with the Oregon R wild line females (hybrid disgenesis). Each line is shown to have a special group of "hot" sites mutating with high frequency under the effect of the oncovirus DNA injected.
mesh_terms: D000818:Animals; D001358:Avian Sarcoma Viruses / Q000235:genetics*; D004279:DNA, Viral / Q000235:genetics*; D004331:Drosophila melanogaster / Q000196:embryology / Q000235:genetics*; D005838:Genotype; D008845:Microinjections; D009154:Mutation; D010063:Ovum; D010957:Plasmids; D014162:Transfection
chemical_list: D004279:DNA, Viral
vernacular_title: Induktsiia nestabil'nykh mutatsiĭ u Drosophila melanogaster mikroin''ektsieĭ DNK onkogennykh virusov v poliarnuiu plazmu émbrionov. Soobshchenie I. Zavisimost' ot genotipa émbriona.