Management of children with hypertension from reflux or obstructive nephropathy.
During a ten-year period, 35 children presenting with vesicoureteral reflux, ureteropelvic junction obstruction, or a "small kidney" were found to be hypertensive. Of these, 15 subsequently underwent surgical procedures for relief of hypertension. Seven were "cured," six were "improved," and two were "unchanged." The severity of hypertension could not be correlated with the degree of reflux nor with the degree of obstructive uropathy. However, all children with reflux in our study who were hypertensive had some degree of calicectasis noted preoperatively on intravenous pyelogram. Also it was noted that hypertension may occur several years after successful anti-reflux surgery. Children with vesicoureteral reflux, ureteropelvic junction obstruction, or a small kidney need to have blood pressure determinations at regular intervals, even if all previous readings had been in the normotensive range and whether or not they were followed up medically or post surgically. We suggest that blood pressure determinations be made every three months for the first year after diagnosis of reflux or ureteropelvic junction obstruction, and at least once a year thereafter.
D000293:Adolescent; D001794:Blood Pressure; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006977:Hypertension, Renal / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D007668:Kidney / Q000002:abnormalities / Q000503:physiopathology; D008297:Male; D009392:Nephrectomy; D012083:Renin / Q000097:blood; D014517:Ureteral Obstruction / Q000150:complications* / Q000601:surgery; D014547:Urinary Diversion; D014718:Vesico-Ureteral Reflux / Q000150:complications* / Q000601:surgery
D012083:Renin