title: Aetiology of acute hepatitis in Malaysia.
abstract: Icteric patients with clinical and biochemical evidence of liver disease, admitted into various hospitals in Malaysia, were investigated to determine the cause of their infection. Of these patients, 11.0% (16/145) were found positive for IgM anti-HAV (EIA), 4.1% (6/145) for IgM anti-HBc (EIA), 1.0% (1/102) for IgM anti-CMV (ELISA), 17.2% (16/64) for rising titres of leptospiral agglutinin, and none for heterophile antibody of EBV. Hepatitis NANB accounted for 67.9% of cases. The mean serum transaminases (ALT and AST) values in patients with hepatitis A and B were higher (more than 500IU) than in patients with leptospirosis or non-A, non-B hepatitis, whereas serum bilirubin levels were higher in patients with hepatitis A and leptospirosis than in patients with hepatitis B.
mesh_terms: D000208:Acute Disease; D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D003586:Cytomegalovirus Infections / Q000209:etiology; D006505:Hepatitis / Q000201:enzymology / Q000209:etiology*; D006506:Hepatitis A / Q000209:etiology; D006509:Hepatitis B / Q000209:etiology; D006526:Hepatitis C / Q000209:etiology; D006801:Humans; D007244:Infectious Mononucleosis / Q000209:etiology; D007922:Leptospirosis / Q000209:etiology; D008296:Malaysia
chemical_list: D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase