Hepatic tumors: dynamic MR imaging.
Thirty-six patients with hepatic tumors (28 hepatocellular carcinomas, seven cavernous hemangiomas, one metastatic tumor) were examined with serial magnetic resonance (MR) imaging, after a bolus intravenous injection of 0.05 mmol/kg gadolinium-diethylenetriaminepentaacetic acid. A typical MR imaging pattern for hemangiomas (present in five of seven cases [71.4%]) was a lesion of diminished signal intensity on precontrast images, peripheral contrast enhancement during the bolus dynamic phase, and complete fill-in of high signal intensity on delayed scan images. Twenty-eight hepatocellular carcinomas showed a variety of contrast enhancement patterns during the dynamic phase. In 21 patients (75%), there was no area of high signal intensity within the tumor on the delayed phase. A peripheral halo with delayed enhancement was noticed in 12 patients (42.8%) Histologic correlation in hepatocellular carcinomas showed that the degree of contrast enhancement corresponded to tumor vascularity and that the peripheral halo corresponded to fibrous capsular structure.
D006528:Carcinoma, Hepatocellular / Q000175:diagnosis*; D005682:Gadolinium; D019786:Gadolinium DTPA; D006392:Hemangioma, Cavernous / Q000175:diagnosis*; D006801:Humans; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000175:diagnosis*; D009682:Magnetic Resonance Spectroscopy; D009942:Organometallic Compounds; D004369:Pentetic Acid
D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA