title: [Supervised bimonthly quadruple chemotherapy in 72 paucibacillary leprosy patients in French Guyana].
abstract: In French Guyana we have treated 72 paucibacillary leprosy with an association of Rifadine + Lamprene + Trecator + Disulone given twice monthly under supervision during 6 months. Results have been satisfying and side effects rare. The sequential character of treatment shows a substantial advantage on the operational side but may appear to be favorable to bacterial resistance.
mesh_terms: D000293:Adolescent; D000328:Adult; D002991:Clofazimine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D003622:Dapsone / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005000:Ethionamide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D005616:French Guiana; D006801:Humans; D007918:Leprosy / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012293:Rifampin / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D004338:Drug Combinations; D003622:Dapsone; D002991:Clofazimine; D005000:Ethionamide; D012293:Rifampin
vernacular_title: Quadruple chimiothérapie bimensuelle supervisée chez 72 paucibacillaires en Guyane française.