title: Cephradine prophylaxis in transurethral procedures for carcinoma of the bladder.
abstract: The value of cephradine prophylaxis in reducing urinary infection was assessed in 243 patients undergoing endoscopy for bladder carcinoma. Patients were randomised either to receive 3 peri-operative doses of cephradine or to receive no antibiotic. Urine specimens taken on the fifth post-operative day showed a significantly lower urinary infection rate in those patients receiving cephradine prophylaxis.
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002295:Carcinoma, Transitional Cell / Q000601:surgery; D002511:Cephalosporins / Q000627:therapeutic use*; D002515:Cephradine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003558:Cystoscopy; D006801:Humans; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*; D011292:Premedication; D011446:Prospective Studies; D011897:Random Allocation; D001749:Urinary Bladder Neoplasms / Q000601:surgery*; D014552:Urinary Tract Infections / Q000517:prevention & control*
chemical_list: D002511:Cephalosporins; D002515:Cephradine