title: [Hereditary nature of nephroblastoma. Apropos of a case of 3 siblings].
abstract: Three nephroblastomas, including one bilateral tumour, have been detected in three children belonging to the same family and born from a consanguinous marriage. The clinical and diagnostic particularities compared to non familial "sporadic" nephroblastomas are studied. The pathogenesis with the incidence of chromosomal anomalies, the diagnosis and the frequency of bilateral diseases along with the associated deformities and a non invasive therapeutic attitude are discussed.
mesh_terms: D002675:Child, Preschool; D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000235:genetics* / Q000628:therapy; D008297:Male; D009392:Nephrectomy; D010375:Pedigree; D009396:Wilms Tumor / Q000235:genetics* / Q000628:therapy
vernacular_title: L'hérédité du néphroblastome. A propos d'une fratrie de trois membres atteints.