Rapid healing of diabetic foot ulcers with meticulous blood glucose control.
Fifteen diabetic patients, with neuropathic food ulcers refractory to conventional treatment, were found to be poorly balanced and were put on meticulous regimens; some on continuous subcutaneous insulin infusion and others on split mixed doses. Once diabetes was controlled, the wound healed rapidly in 11 of the patients within 4 to 13 weeks. In 4 patients amputation was necessary. The outcome was better in patients with good peripheral pulses. We suggest that tight control of diabetes promotes healing of diabetic foot lesions.
D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000503:physiopathology; D003929:Diabetic Neuropathies / Q000097:blood / Q000503:physiopathology*; D005534:Foot Diseases / Q000503:physiopathology* / Q000628:therapy; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010349:Patient Compliance; D012883:Skin Ulcer / Q000503:physiopathology* / Q000628:therapy; D014945:Wound Healing
D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007328:Insulin