[Detection of type 1 and 2 herpetic antigens by immunofluorescence in patients with chronic or recurrent keratoconjunctivitis receiving therapy based on etiology].
Immunofluorescence (IF) techniques were used to evaluate the therapeutical efficiency of moroxidine hydrochloride against herpes virus (HSV) induced keratoconjunctivitis. In 56 out of the 77 followed-up and treated patients, the IF reactions revealed the presence of both types 1 and 2 of herpes virus, while in 21 only type 1 was found. The treatment with moroxidine hydrochloride led to a reduction of 63% and 92%, respectively, of the incidence of herpes virus type 1 and 2 antigens in the conjunctival cells, coincident with the improvement of clinical symptoms or persistent recovery.
D000956:Antigens, Viral / Q000032:analysis*; D000998:Antiviral Agents / Q000627:therapeutic use; D001645:Biguanides; D002908:Chronic Disease; D004341:Drug Evaluation; D005455:Fluorescent Antibody Technique; D006801:Humans; D007635:Keratitis, Dendritic / Q000188:drug therapy / Q000276:immunology*; D007637:Keratoconjunctivitis / Q000188:drug therapy / Q000276:immunology*; D009025:Morpholines / Q000627:therapeutic use; D012008:Recurrence; D018139:Simplexvirus / Q000276:immunology*
D000956:Antigens, Viral; D000998:Antiviral Agents; D001645:Biguanides; D009025:Morpholines; C005267:moroxydine
Incidence des antigènes herpétiques des types 1 et 2 décelés en immunofluorescence chez des malades souffrant de kérato-conjonctivite chronique ou récidivante, soumis à une thérapeutique étiologique.