title: Comparison of the antimicrobial capability of an abrasive paste and chemical-soak denture cleaners.
abstract: The objective of this research was to compare the ability of the two most popular methods for denture cleaning to remove plaque microorganisms from dentures. Dentu-Creme abrasive denture paste and Efferdent alkaline peroxide denture-cleanser soak were selected for study. Two trials were completed in which these materials were used alone and in combination along with a no-treatment control to determine the level of recoverable plaque bacteria from removable dentures. Plaque was allowed to accumulate for 48 or 72 hours in individuals with healthy oral mucosa during which time they refrained from all denture hygiene procedures. The results of two studies following similar double-blind cross-over designs were consistent in that soaking with the denture cleanser caused a significantly greater reduction of microorganisms than did brushing with the denture paste. Further, combining brushing with the soak did not reduce the level of recoverable microorganisms significantly more than soaking alone. Overall, brushing alone did not consistently remove more microorganisms than were observed in the no-treatment group. The denture-cleanser soak displayed broad antimicrobial activity against gram-negative anaerobic rods (Fusobacterium sp.), gram-positive facultative cocci (streptococci), and gram-negative anaerobic cocci (Veillonella sp.), as well as total recoverable microorganisms, which were all equally reduced by the denture-cleanser treatment. These results support the need for use of a denture cleanser in addition to brushing with a denture paste for proper denture hygiene.
mesh_terms: D001419:Bacteria / Q000302:isolation & purification; D002986:Clinical Trials as Topic; D015169:Colony Count, Microbial; D003773:Dental Plaque / Q000382:microbiology*; D003802:Dentifrices; D003820:Denture Cleansers; D003827:Denture, Complete, Upper; D003832:Denture, Partial, Removable; D004311:Double-Blind Method; D006801:Humans; D011897:Random Allocation
chemical_list: D003802:Dentifrices; D003820:Denture Cleansers