title: [1H-NMR study of the peptide corresponding to the ACTH-like sequence of the variable region of human G1 Eu heavy chain immunoglobin].
abstract: Synthetic decapeptide corresponding to ACTH-like sequence of the variable part of the heavy chain of immunoglobulin G1 Eu was studied by two-dimensional 1H-NMR spectroscopy (400 MHz). A complete assignment of signals in the peptide spectrum was made. The decapeptide was shown not to have any ordered spatial structure, and was characterized by a high extent of flexibility of the oligopeptide chain, except for the peptide bond with an N-terminal residue.
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000032:analysis*; D003366:Cosyntropin / Q000032:analysis* / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007143:Immunoglobulin Heavy Chains / Q000032:analysis*; D007135:Immunoglobulin Variable Region / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D010446:Peptide Fragments / Q000032:analysis* / Q000276:immunology
chemical_list: D007074:Immunoglobulin G; D007143:Immunoglobulin Heavy Chains; D007135:Immunoglobulin Variable Region; D010446:Peptide Fragments; D003366:Cosyntropin; C034016:ACTH (11-24); D000324:Adrenocorticotropic Hormone
vernacular_title: 1H-IaMR-issledovanie peptida, sootvetstvuiushchego AKTG-podobnoĭ posledovatel'nosti variabel'noĭ chasti tiazheloĭ tsepi immunoglobulina G1 Eu cheloveka.