Studies on antiviral agents. V. Synthesis and in vitro antiviral activity of new aminoglycoside derivatives having palmitoyl group.
The synthesis and antiviral activity of various aminoglycoside derivatives having a palmitoyl group are described. All of these aminoglycoside derivatives exhibited almost the same excellent antiviral activity against herpes simplex virus type I and influenza virus.
D000617:Aminoglycosides / Q000138:chemical synthesis* / Q000494:pharmacology; D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D009975:Orthomyxoviridae / Q000187:drug effects; D010168:Palmitates; D010169:Palmitic Acids; D018139:Simplexvirus / Q000187:drug effects; D013329:Structure-Activity Relationship
D000617:Aminoglycosides; D000998:Antiviral Agents; D010168:Palmitates; D010169:Palmitic Acids