title: [Effect of melanin on the free-radical states of gamma-irradiated proteins and lipids].
abstract: It was shown that the concentration of paramagnetic centres of dihydroxyphenylalanine-melanin increased after gamma-irradiation (60Co) both at room temperature (an irreversible increase) and at 77 K (a reversible increase). The accumulation of paramagnetic centres in gamma-irradiated albumin at room temperature was found to slow down appreciably in the presence of melanin. This effect is thought to be associated with the antiradical activity of the pigment.
mesh_terms: D000418:Albumins / Q000528:radiation effects*; D003037:Cobalt Radioisotopes; D004295:Dihydroxyphenylalanine / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals; D005720:Gamma Rays; D066298:In Vitro Techniques; D008055:Lipids / Q000528:radiation effects*; D012996:Solutions; D013696:Temperature
chemical_list: D000418:Albumins; D003037:Cobalt Radioisotopes; D005609:Free Radicals; D008055:Lipids; D012996:Solutions; D004295:Dihydroxyphenylalanine; C040616:DOPA melanin
vernacular_title: Vliianie melanina na svobodno-radikal'nye sostoianiia gamma-obluchennykh belkov i lipidov.