Plasmacytoid T cells. Immunohistochemical evidence for their monocyte/macrophage origin.
To elucidate the lineage of plasmacytoid T cells, their immunophenotype was studied in reactive lymph nodes with a broad panel of monoclonal antibodies. Plasmacytoid T cells expressed several myelomonocytic markers, and almost all markers highly selective for macrophages. They lacked granulocyte-associated and B or T lymphocyte-associated antigens. These results provide strong evidence that plasmacytoid T cells are of monocyte lineage.
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface / Q000032:analysis; D006801:Humans; D007124:Immunoenzyme Techniques; D008198:Lymph Nodes / Q000473:pathology; D008264:Macrophages / Q000145:classification*; D009000:Monocytes / Q000145:classification*; D010641:Phenotype; D013601:T-Lymphocytes / Q000145:classification* / Q000276:immunology
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface