title: Molecular cloning and sequence analysis of the human parainfluenza 3 virus gene encoding the matrix protein.
abstract: The sequence of the matrix (M) protein gene and contiguous intergenic regions of the human parainfluenza 3 virus (PF3) was determined by molecular cloning. The encoded M protein contains 354 amino acids and has a predicted mol wt of 39,506. The M protein amino acid sequence was compared to the homologous proteins from other members of the Paramyxoviridae family. The PF3 protein shared 61% homology with the Sendai virus protein and approximately 35% homology with measles and canine distemper virus proteins. Little homology was observed with respiratory syncytial virus. The M protein appears to be the most highly conserved among the Paramyxoviridae proteins.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D005796:Genes; D005814:Genes, Viral; D010224:Parainfluenza Virus 3, Human / Q000235:genetics*; D018108:Respirovirus / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D014763:Viral Matrix Proteins; D014764:Viral Proteins / Q000235:genetics*
chemical_list: D014763:Viral Matrix Proteins; D014764:Viral Proteins