title: Presence of cytomegalovirus in brown fat. Study in a rat model.
abstract: Cytomegalovirus infection of laboratory rats resulted in the appearance of virus and viral antigens in interscapular and periaortic brown fat. This appearance was limited to acute infection (first week post-infection) and was dependent on the route of inoculation. In our study virus could only be detected in subcutaneous brown fat in young rats (till 4 weeks of age), whereas in the deep brown fat (periaortic region) no age dependency was found.
mesh_terms: D000005:Abdomen; D000208:Acute Disease; D002001:Adipose Tissue, Brown / Q000382:microbiology*; D000367:Age Factors; D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D001415:Back; D002478:Cells, Cultured; D003587:Cytomegalovirus / Q000276:immunology / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000382:microbiology / Q000473:pathology; D007274:Injections, Intraperitoneal; D007279:Injections, Subcutaneous; D051381:Rats; D011914:Rats, Inbred BN; D011917:Rats, Inbred Lew
chemical_list: D000956:Antigens, Viral