Technetium-99m pyrophosphate single-photon emission computed tomography of the heart in familial amyloid polyneuropathy.
A patient with familial amyloid polyneuropathy and congestive heart failure underwent myocardial imaging using technetium-99m pyrophosphate. Planar scintigraphy showed an intense, diffuse biventricular uptake of the radiotracer. Single-photon emission computed tomography demonstrated an unevenly distributed uptake of the isotope. The greatest activity corresponded to regions with marked echocardiographic changes. Emission tomography may aid in assessing the degree and distribution of the infiltrative lesions in cardiac amyloidosis.
D000368:Aged; D000686:Amyloidosis / Q000000981:diagnostic imaging* / Q000235:genetics; D011756:Diphosphates; D004452:Echocardiography; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D011115:Polyneuropathies / Q000000981:diagnostic imaging* / Q000235:genetics; D013667:Technetium; D016698:Technetium Tc 99m Pyrophosphate; D014055:Tomography, Emission-Computed
D011756:Diphosphates; D016698:Technetium Tc 99m Pyrophosphate; D013667:Technetium