[A monoclonal antibody against peripheral human blood monocytes (RoMo-1)].
The monoclonal IgG2a-antibody RoMo-1 binds to peripheral human blood monocytes but does not react with other blood cells, tissue macrophages, HL-60, K 562 or U 937. It seems possible, that the antibody defines an antigen expressed on the premonocytic and monocyte stages of cells from the mononuclear phagocytic system only. The antibody is cytotoxic.
D000911:Antibodies, Monoclonal / Q000276:immunology*; D000918:Antibody Specificity; D002448:Cell Adhesion; D002460:Cell Line; D006098:Granulocytes / Q000276:immunology; D006801:Humans; D007124:Immunoenzyme Techniques; D008264:Macrophages / Q000276:immunology; D009000:Monocytes / Q000276:immunology*; D011650:Pulmonary Alveoli / Q000276:immunology; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology
D000911:Antibodies, Monoclonal
Ein monoklonaler Antikörper gegen periphere menschliche Blutmonozyten (RoMo-1).