title: [Neurological manifestations of Behçet's disease].
abstract: Characterised classically by the association of buccal and genital ulceration and uveitis with hypopyon, Behçet's disease has many other manifestations, amongst which the neurological ones (often referred to as Neuro-Behçet) are important in view of their frequency and their gravity. Anatomically, it produces a subacute haemorrhagic and necrotising meningo-encephalitis, which most typically effects the hypothalamus and brainstem. Clinically, there is extreme polymorphism, central manifestations being the most frequent: seizures, organic brain syndromes, disorders of consciousness, aphasia, hemiplegia, cranial nerve palsies, pseudobulbar and extrapyramidal syndromes and meningism. The peripheral nerves and muscles are rarely affected. Alongside Neuro-Behçet per se, attention has recently been directed to the various cerebro-vascular manifestations, dominated by venous thrombosis. A review of the principal neurological manifestations is given, with comment on anatomico-pathological aspects, clinical presentation, investigational techniques, diagnostic difficulties, prognosis, and treatment.
mesh_terms: D001528:Behcet Syndrome / Q000150:complications*; D002543:Cerebral Hemorrhage / Q000209:etiology; D002561:Cerebrovascular Disorders / Q000209:etiology; D006801:Humans; D008590:Meningoencephalitis / Q000209:etiology; D009336:Necrosis / Q000209:etiology; D009422:Nervous System Diseases / Q000209:etiology*; D019965:Neurocognitive Disorders / Q000209:etiology
vernacular_title: Les manifestations neurologiques de la maladie de Behçet.