Premarket evaluation of Monofluor reagent for detecting Chlamydia trachomatis in adolescent outpatients.
A new direct fluorescent antibody reagent, Monofluor, was evaluated for detecting Chlamydia trachomatis in fresh specimens. Monofluor was compared with Micro Trak and with cultivation in McCoy cells. Both direct systems were slightly less sensitive than culture, but no significant differences in specificity or sensitivity were noted between culture, Monofluor, or Micro Trak results.
D000293:Adolescent; D000942:Antigens, Bacterial; D002692:Chlamydia trachomatis / Q000276:immunology / Q000302:isolation & purification*; D005069:Evaluation Studies as Topic; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity
D000942:Antigens, Bacterial; D011933:Reagent Kits, Diagnostic