title: Clinical trials with long-term treatment of pulmonary hypertension due to lung disease.
abstract: Many drugs have been tested for the treatment of pulmonary hypertension of different origins, but even the acute effects are controversial and side-effects are frequently important. In a few studies, vasodilators have been used in the long-term treatment of chronic pulmonary hypertension related to chronic lung disease (calcium channel blockers, hydralazine, nitrates); here, also, the results are inconstant and the side-effects are sometimes major. No vasodilator specific for the pulmonary circulation is presently available.
mesh_terms: D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy* / Q000209:etiology; D008173:Lung Diseases, Obstructive / Q000150:complications*; D014665:Vasodilator Agents / Q000627:therapeutic use*
chemical_list: D014665:Vasodilator Agents