title: [Unilateral sensory neuropathy of the trigeminal nerve as the leading symptom of primary Sjögren syndrome ("sicca syndrome")].
abstract: We report a case who presenting with a progressive numbness and mild hyperpathia in the second cutaneous division of the left trigeminal nerve as the leading symptom of Primary Sjögren's Syndrome. Further typical features of this autoimmune disorder are keratoconjunctivitis sicca and xerostomia. A symmetrical, predominantly sensory polyneuropathy can be revealed by sensory nerve conduction studies of the median and sural nerves. Laboratory findings mostly include elevated erythrocyte sedimentation rate, hypergammaglobulinemia and hypercomplementemia. The presence of the precipitating antinuclear antibodies SS-A and/or SS-B is pathognomonic for Sjögren's Syndrome. As long as the disease remains benign, treatment should be symptomatic. Malignant exacerbations require immunosuppressive treatment.
mesh_terms: D000328:Adult; D003389:Cranial Nerve Diseases / Q000175:diagnosis; D005260:Female; D006801:Humans; D006987:Hypesthesia / Q000175:diagnosis*; D011115:Polyneuropathies / Q000175:diagnosis*; D012859:Sjogren's Syndrome / Q000175:diagnosis*; D009435:Synaptic Transmission; D014276:Trigeminal Nerve
vernacular_title: Einseitige sensorische Neuropathie des N. trigeminus als Leitsymptom eines primären Sjögren-Syndroms ("Sicca-Syndrom").