title: [The interface between hydroxyapatite ceramic and newly formed bone in scanning electron microscopy].
abstract: Bone samples, which have been embedded in methylmethacrylate in an undecalcified state can be evaluated by a scanning electron microscopy after removal of the methylmethacrylate. Hydroxy apatite (HA) has been implanted in 6 mm bore holes of the rabbits' femoral condyle. The animals were sacrificed after 2, 4, 6, 8 weeks and 8 months. The interface between HA and the newly built bone was observed. A direct contact has been found regularly through high magnification (up to 16,000 times). The three dimensional embedding of the implanted HA-particles into the newly built bone can be shown. Collagen filaments are spreading out from bone to HA-particles. We think that there is not only a mechanical but also a chemical connection between both.
mesh_terms: D000818:Animals; D001861:Bone Regeneration; D001842:Bone and Bones / Q000473:pathology*; D002516:Ceramics; D017886:Durapatite; D006882:Hydroxyapatites; D008855:Microscopy, Electron, Scanning; D019736:Prostheses and Implants; D011817:Rabbits; D014945:Wound Healing
chemical_list: D006882:Hydroxyapatites; D017886:Durapatite
vernacular_title: Die Grenzschicht zwischen Hydroxylapatit-Keramik und neugebildetem Knochen im Rasterelektronenmikroskop.