The measurement of free radical reactions in humans. Some thoughts for future experimentation.
The question as to whether free radical reactions are a major cause of tissue injury in human disease, or merely an accompaniment to such injury, is very difficult to answer because of lack of adequate experimental techniques. New techniques that are becoming available are discussed, with specific reference to their use in humans.
D004247:DNA / Q000187:drug effects; D004194:Disease / Q000503:physiopathology*; D005609:Free Radicals; D005979:Glutathione Peroxidase / Q000378:metabolism; D006801:Humans; D006878:Hydroxides; D017665:Hydroxyl Radical; D006900:Hydroxylation; D008054:Lipid Peroxides / Q000378:metabolism; D010084:Oxidation-Reduction; D013482:Superoxide Dismutase / Q000378:metabolism; D013481:Superoxides / Q000378:metabolism
D005609:Free Radicals; D006878:Hydroxides; D008054:Lipid Peroxides; D013481:Superoxides; D017665:Hydroxyl Radical; D004247:DNA; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase