[Role of the membranes in lymphocyte interaction with mycoplasmas].
The interaction of Acheleplasma laidlawii cells, derived membranes and liposomes with mouse spleen lymphocytes does not require the energy and participation of electrostatic coupling. The absence of pinocytosis of mycoplasma is demonstrated. Specific membrane receptors don't participate in mycoplasma and lymphocyte binding. The exchange by membrane lipids occurs during the interaction of mycoplasma, membranes and liposomes with lymphocytes; mycoplasma, membranes and liposomes lose saturated fat acids and enrich with cholesterol. On the contrary, lymphocytes lose cholesterol, but absorb fat acids. The intensity of lipid exchange depends on the degree of unsaturation of fat acids in mycoplasma. The carbohydrate transport into lymphocytes is stimulated considerably as a result of interaction of both cells.
D000128:Acholeplasma laidlawii / Q000187:drug effects / Q000378:metabolism*; D000818:Animals; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D002784:Cholesterol / Q000378:metabolism; D004347:Drug Interactions; D005227:Fatty Acids / Q000378:metabolism; D008081:Liposomes / Q000378:metabolism; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism*; D008563:Membrane Lipids / Q000378:metabolism; D051379:Mice; D011956:Receptors, Cell Surface / Q000187:drug effects / Q000378:metabolism; D013154:Spleen / Q000166:cytology
D005227:Fatty Acids; D008081:Liposomes; D008563:Membrane Lipids; D011956:Receptors, Cell Surface; D002784:Cholesterol
Rol' membran vo vzaimodeĭstvii limfotsitov s mikoplazmami.