Prospective study of carbohydrate metabolism in women using a triphasic oral contraceptive containing norethindrone and ethinyl estradiol for 3 months.
Thirty-five women with normal carbohydrate metabolism were administered a 3-hour oral glucose tolerance test before and after 3 months' use of a triphasic oral contraceptive that contained ethinyl estradiol and norethindrone. The results show no significant change in either the plasma glucose or the insulin values. This is the first published study with regard to this type of triphasic oral contraceptive, and the study supports claims of the preparation's improved safety.
D000293:Adolescent; D000328:Adult; D003280:Contraceptives, Oral, Synthetic / Q000494:pharmacology*; D004997:Ethinyl Estradiol / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D005947:Glucose / Q000378:metabolism*; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000097:blood; D009640:Norethindrone / Q000008:administration & dosage / Q000494:pharmacology*; D011446:Prospective Studies
D003280:Contraceptives, Oral, Synthetic; D007328:Insulin; D004997:Ethinyl Estradiol; D005947:Glucose; D009640:Norethindrone