Drug-induced vascular and sinusoidal lesions of the liver.
Drugs can induce various vascular and sinusoidal lesions of the liver, in particular hepatic vein thrombosis, veno-occlusive disease, sinusoidal dilatation, peliosis hepatis, hepatoportal sclerosis and angiosarcoma. None of these lesions is specific of drug-induced injury and all of them can be determined by causes other than drugs. However, for one of these lesions, veno-occlusive disease, chemotherapy (and/or irradiation) represents the main aetiology.
D006502:Budd-Chiari Syndrome / Q000139:chemically induced*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D064420:Drug-Related Side Effects and Adverse Reactions; D006504:Hepatic Veno-Occlusive Disease / Q000139:chemically induced*; D006801:Humans; D008113:Liver Neoplasms / Q000139:chemically induced*; D010382:Peliosis Hepatis / Q000139:chemically induced*