title: Bimorphinans as highly selective, potent kappa opioid receptor antagonists.
mesh_terms: D000818:Animals; D006168:Guinea Pigs; D008297:Male; D051379:Mice; D009019:Morphinans / Q000138:chemical synthesis* / Q000494:pharmacology; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology; D011957:Receptors, Opioid / Q000187:drug effects* / Q000378:metabolism; D017473:Receptors, Opioid, kappa; D013329:Structure-Activity Relationship
chemical_list: D009019:Morphinans; D011957:Receptors, Opioid; D017473:Receptors, Opioid, kappa