title: Granular cell tumor of the ascending colon: a case report.
abstract: A granular cell tumor (granular cell myoblastoma) of the ascending colon in a 48-year old male is reported. The tumor was detected by barium enema study as a sessile polyp, and colonofiberscopy revealed submucosal tumor. It was removed by endoscopic polypectomy. Macroscopic examination showed the characteristic features of granular cell tumor. The avidin-biotin-peroxidase complex (ABC) method for detection of S-100 protein demonstrated that the cytoplasm of tumor cells and the pleomorphic nuclei were strongly stained with anti-S-100 protein serum, which supports the concept of the Schwann cell origin of granular cell tumor.
mesh_terms: D003110:Colonic Neoplasms / Q000032:analysis / Q000473:pathology* / Q000601:surgery; D003113:Colonoscopy; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009379:Neoplasms, Muscle Tissue / Q000032:analysis / Q000473:pathology* / Q000601:surgery; D009418:S100 Proteins / Q000032:analysis
chemical_list: D009418:S100 Proteins