[Rickettsiaceae infections and fluoroquinolones].
Twenty nine patients with Rickettsiosis (Tick born fever, n: 22, Q fever, n: 7) has been treated with fluoroquinolones. These compounds was used alone n: 25 (Pefloxacin, n: 15; Ofloxacin, n: 10) or associated n: 4 (Pefloxacin + Rifampin). The general efficacy was excellent. Common Tick born fever and pulmonary forms of Q fever was fast cured. Severe Tick born fever (neurologic or polyvisceral forms, n: 5) and Q fever with long term hyperthermia, n: 4 cas always cured without complications but the time necessary to obtain apyrexia was often longer (6 cases).
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001907:Boutonneuse Fever / Q000188:drug therapy*; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009643:Norfloxacin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D015242:Ofloxacin; D010078:Oxazines / Q000008:administration & dosage / Q000627:therapeutic use*; D015366:Pefloxacin; D011247:Pregnancy; D011778:Q Fever / Q000188:drug therapy*; D012293:Rifampin / Q000008:administration & dosage / Q000627:therapeutic use
D000890:Anti-Infective Agents; D010078:Oxazines; D015366:Pefloxacin; D015242:Ofloxacin; D009643:Norfloxacin; D012293:Rifampin
Infections par les rickettsiales et fluoroquinolones.