title: Terminal inverted repeats of prokaryotic transposable element IS186 which can generate duplications of variable length at an identical target sequence.
abstract: The insertion element IS186, which resides in the chromosome of Escherichia coli K-12, is 1338 bp long. Its termini represent 23-bp perfectly inverted repeats, but a variant carries a mismatch at position 23. IS186 transposes preferentially into G + C-rich sequences and generates target duplications of variable length, even at the same integration site.
mesh_terms: D001482:Base Composition; D001483:Base Sequence; D002876:Chromosomes, Bacterial / Q000502:physiology; D004251:DNA Transposable Elements; D004926:Escherichia coli / Q000235:genetics*; D005798:Genes, Bacterial; D012091:Repetitive Sequences, Nucleic Acid
chemical_list: D004251:DNA Transposable Elements