title: [Proton therapy: clinico-methodological aspects, treatment results].
abstract: In the period of 1975-1986, 457 patients (81 with breast and prostatic cancer, 24 with endocrine ophthalmopathy, 20 with diabetic angioretinopathy, 206 with pituitary adenomas, 115 with arteriovenous and 6 with arterial brain malformations, and 6 with epilepsy) were given proton beam therapy at the Central Research Roentgenoradiology Institute using the 1000 MeV synchrocyclotron of the Leningrad Institute for Nuclear Physics. A prolonged remission was noted in 75-90% of the patients with pituitary adenomas. Angiography showed complete exclusion of aneurysm from the blood flow 2 yrs. after irradiation almost in 50% of the patients with arteriovenous malformations. A high efficacy and safety of the method was shown.
mesh_terms: D001943:Breast Neoplasms / Q000532:radiotherapy; D003480:Cushing Syndrome / Q000532:radiotherapy; D003930:Diabetic Retinopathy / Q000532:radiotherapy; D005260:Female; D006111:Graves Disease / Q000532:radiotherapy; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000532:radiotherapy; D008297:Male; D010315:Particle Accelerators; D010911:Pituitary Neoplasms / Q000532:radiotherapy; D011522:Protons; D011882:Radiotherapy, High-Energy / Q000295:instrumentation
chemical_list: D011522:Protons
vernacular_title: Protonnaia terapiia: kliniko-metodicheskie aspekty, rezul'taty lecheniia.