title: The proteins of equid herpesvirus 1 (EHV 1) recognised by equine antisera and their ability to promote antibody-dependent cell-mediated cytotoxicity.
abstract: Equine sera were used to immunoprecipitate radiolabelled virus-infected cell proteins; subsequent resolution with polyacrylamide gel electrophoresis identified the EHV-1 polypeptides VP 2, 10a, 11, 13, 14, 15, 16, 20, 21 and 23a. The humoral support of ADCC by these sera was examined in vitro. Cytotoxicity could be demonstrated against both subtypes irrespective of the immunising isolate. The implications of these results are discussed.
mesh_terms: D000818:Animals; D000920:Antibody-Dependent Cell Cytotoxicity; D000956:Antigens, Viral / Q000276:immunology*; D004591:Electrophoresis, Polyacrylamide Gel; D005856:Germ-Free Life; D006564:Herpesviridae / Q000276:immunology*; D004861:Herpesvirus 1, Equid / Q000276:immunology*; D006736:Horses; D007106:Immune Sera / Q000276:immunology; D007158:Immunologic Techniques; D009504:Neutrophils / Q000276:immunology; D010455:Peptides / Q000276:immunology; D014764:Viral Proteins / Q000276:immunology*
chemical_list: D000956:Antigens, Viral; D007106:Immune Sera; D010455:Peptides; D014764:Viral Proteins