[Interrelation of the hormonal indices and the cytologic characteristics of the germ cells].
The analysis of the maturation of follicular oocytes as well as of the state of gametes after induction of ovulation with PMSG or with GnRH in intact and androgenized rats revealed the dependence of the heterogeneity extent (in morphologic and chromosomal damages) of population of germ cells maturing in vivo and in vitro upon the character of gonadotropin regulation disturbances of folliculogenesis. Stable disorder of reproductive function (androgenization) is followed by a significant increase in number of abnormal gametes under its hormonal correction.
D000818:Animals; D000831:Animals, Newborn; D002869:Chromosome Aberrations; D004958:Estradiol / Q000097:blood*; D004971:Estrus / Q000187:drug effects; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology; D006065:Gonadotropins, Pituitary / Q000097:blood*; D009865:Oocytes / Q000166:cytology* / Q000187:drug effects; D006080:Ovarian Follicle / Q000166:cytology / Q000187:drug effects / Q000502:physiology; D010062:Ovulation Induction; D011374:Progesterone / Q000097:blood*; D051381:Rats; D013739:Testosterone / Q000494:pharmacology; D014621:Vagina / Q000002:abnormalities
D006065:Gonadotropins, Pituitary; D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone; D011374:Progesterone; D004958:Estradiol
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