title: A transmission line modelling approach to the interpretation of uterine Doppler waveforms.
abstract: An electrical analogue model of an artery that terminates into a vascular bed is presented. The model consists of an uniform transmission line that represents the artery and a load impedance that represents the vascular bed. The transmission line parameters are based on a well-established first-order approximation of the Navier-Stokes equations for fluid flow in distensible tubes. The model can be used to predict the incident and reflected components of both the arterial pressure and flow waveforms. In addition, it can predict the vessel diameter change and the mean blood velocity waveforms. In this study, the model was applied to the uterine artery so that the characteristics of the utero-placental circulation can be related to Doppler ultrasound recordings. It was found that the presence of the dicrotic notch in the uterine artery time-velocity waveform is the result of wave reflection and that a persistent notch past 20 weeks' gestation may be indicative of an abnormally high placental bed resistance. It is shown that the simulation results are consistent with the known physiological data and the clinically recorded uterine Doppler waveforms.
mesh_terms: D001158:Arteries / Q000033:anatomy & histology; D003198:Computer Simulation; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008954:Models, Biological; D011247:Pregnancy; D012039:Regional Blood Flow; D012212:Rheology; D014465:Ultrasonics; D014463:Ultrasonography / Q000379:methods*; D014599:Uterus / Q000098:blood supply*