title: Histochemical changes in the testes of lead induced experimental rats.
abstract: The experiments were performed on mature male rats divided in five groups, one control and four experimental in which the animals received 1 mg, 2 mg, 4 mg and 6 mg/kg body weight lead acetate intraperitoneally respectively, over a period of 30 days. ALA-D and lead was estimated in the blood by the use of atomic absorption spectrophotometer and ATP-ase, AMP-ase, Alk-ase were histochemically localized. Significant increase in blood and testis of lead levels along with decrease of ALA-D levels were observed. Changes in the testicular tissue were encountered. Other details concerned with the damage of the testicular tissue are discussed.
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D001485:Basement Membrane / Q000378:metabolism; D006651:Histocytochemistry; D007854:Lead / Q000378:metabolism / Q000633:toxicity*; D008297:Male; D009708:Nucleotidases / Q000378:metabolism; D000623:Porphobilinogen Synthase / Q000378:metabolism; D051381:Rats; D012671:Seminiferous Tubules / Q000378:metabolism; D013737:Testis / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology
chemical_list: D007854:Lead; D009708:Nucleotidases; C018775:adenosine monophosphatase; D000469:Alkaline Phosphatase; D000251:Adenosine Triphosphatases; D000623:Porphobilinogen Synthase