Failure in chymotrypsin enhancement of human rotavirus infectivity.
Effects of alpha-chymotrypsin on human rotavirus infectivity and hemagglutination activity were investigated using the KUN strain which was grown in the absence of trypsin and noninfectious. No activating effect of the enzyme on the virus infectivity was found, while HA titers of the virus rapidly decreased after exposure to the enzyme.
D002384:Catalysis; D002918:Chymotrypsin / Q000494:pharmacology*; D006389:Hemagglutinins, Viral / Q000032:analysis*; D012401:Rotavirus / Q000187:drug effects* / Q000276:immunology / Q000472:pathogenicity
D006389:Hemagglutinins, Viral; D002918:Chymotrypsin