[The state of immunity and the cyclic nucleotide system in the radiotherapy of breast cancer].
Indices of the T-system of immunity were lowered in breast cancer patients. Small fractional radiotherapy resulted in its greater suppression. A tumor revealed low pathomorphosis accompanied by a sharp increase in the levels of cyclic nucleotides. Large fractional radiotherapy caused no changes in the state of the immune system correlating with high radiation pathomorphosis in a tumor and a decrease in a cGMP level.
D000328:Adult; D001943:Breast Neoplasms / Q000276:immunology / Q000378:metabolism / Q000532:radiotherapy*; D000242:Cyclic AMP / Q000378:metabolism*; D006152:Cyclic GMP / Q000378:metabolism*; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000528:radiation effects*; D008875:Middle Aged
D000242:Cyclic AMP; D006152:Cyclic GMP
Sostoianie immuniteta i sistemy tsiklicheskikh nukleotidov pri luchevoĭ terapii raka molochnoĭ zhelezy.