New evidence on the nature of hypocorticism in thymomegaly.
According to the present clinical-experimental investigations, hypocorticism at the thymomegaly (hyperplasia of the thymus) was shown to occur as the secondary phenomenon as a result of the reduction of the corticotrophin function of adenohypophysis due to the activation of dopaminergic and serotoninergic central inhibition systems.
D015062:11-Hydroxycorticosteroids / Q000097:blood; D000302:Adrenal Cortex / Q000378:metabolism*; D000324:Adrenocorticotropic Hormone / Q000097:blood; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D006965:Hyperplasia / Q000378:metabolism; D007223:Infant; D008297:Male; D013950:Thymus Gland / Q000473:pathology*
D015062:11-Hydroxycorticosteroids; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone