Cytomegalovirus retinitis in rheumatic disease: a case report.
We describe a 67-year-old white man with Wegener's granulomatosis who was treated with cyclophosphamide, then with azathioprine, and who subsequently developed cytomegalovirus retinitis. The patient initially improved on a course of adenine arabinosine, but his retinitis has progressed, despite discontinuation of immunosuppressive therapy. We show that cytomegalovirus retinitis does occur in patients with rheumatic diseases who receive immunosuppressive therapy.
D000328:Adult; D001379:Azathioprine / Q000009:adverse effects / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000009:adverse effects / Q000627:therapeutic use; D003586:Cytomegalovirus Infections; D014890:Granulomatosis with Polyangiitis / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D012173:Retinitis / Q000150:complications* / Q000209:etiology; D012216:Rheumatic Diseases / Q000150:complications*
D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D001379:Azathioprine