Adherence of Campylobacter jejuni and Campylobacter coli to porcine intestinal brush border membranes.
The adhesion of Campylobacter jejuni and C. coli to isolated porcine intestinal brush border membranes was studied by phase-contrast and electron microscopy. Approximately 45% of the cell population adhered to the brush borders, possibly in a specific manner. Pretreatment of the brush borders with trypsin or pronase, and competitive inhibition with L-rhamnose caused a slight reduction of the adhesion. Different forms of pretreatment of the bacterial cells reduced their ability to adhere, but also their motility.
D000596:Amino Acids / Q000494:pharmacology; D000606:Amino Sugars / Q000494:pharmacology; D000818:Animals; D001422:Bacterial Adhesion / Q000187:drug effects; D002167:Campylobacter / Q000187:drug effects / Q000502:physiology*; D002168:Campylobacter fetus / Q000187:drug effects / Q000502:physiology*; D002241:Carbohydrates / Q000494:pharmacology; D006801:Humans; D007421:Intestine, Small / Q000187:drug effects / Q000382:microbiology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D008858:Microscopy, Phase-Contrast; D008871:Microvilli / Q000187:drug effects / Q000382:microbiology / Q000648:ultrastructure; D011402:Pronase / Q000494:pharmacology; D013552:Swine; D014357:Trypsin / Q000494:pharmacology
D000596:Amino Acids; D000606:Amino Sugars; D002241:Carbohydrates; D014357:Trypsin; D011402:Pronase