title: An in vitro evaluation of the prevention of caries on overdenture abutments.
abstract: Teeth prepared as overdenture abutments are susceptible to caries, and it has been shown that brushing by itself is not sufficient to prevent this process. This study evaluated the preventive effect of a remineralization gel which has a low fluoride concentration and compared its effects with those of a phosphate fluoride gel (Karigel), which has a much higher concentration of fluoride. Twenty extracted anterior teeth from patients aged 50 to 70 years were prepared as for overdenture abutments. Each tooth was sectioned into three fragments. An acidified gel system was used to produce artificial caries lesions on the occlusal and root surfaces of each fragment. One fragment of each tooth was treated with the remineralizing gel, the second fragment with a high-fluoride gel, and the third fragment served as the control. Ten teeth were removed at two weeks and again at four weeks, and were sectioned and prepared for histological examination. The depth of the lesions was measured from standardized photomicrographs by means of a sonic digitizer. The conclusions were: (1) Lesions on the occlusal tended to be deeper than those on the root surfaces at four weeks but not at two weeks; and (2) the high-fluoride gel was more protective than the low-fluoride remineralizing solution at both time periods on the occlusal but not on the root surface.
mesh_terms: D000368:Aged; D002118:Calcium / Q000008:administration & dosage / Q000627:therapeutic use; D000044:Dental Abutments; D003731:Dental Caries / Q000517:prevention & control*; D003804:Dentin / Q000187:drug effects*; D003828:Denture, Overlay; D005459:Fluorides / Q000008:administration & dosage / Q000627:therapeutic use; D005782:Gels; D006801:Humans; D008875:Middle Aged; D010710:Phosphates / Q000008:administration & dosage / Q000627:therapeutic use; D011897:Random Allocation; D014092:Tooth Root / Q000187:drug effects*
chemical_list: D005782:Gels; D010710:Phosphates; D005459:Fluorides; D002118:Calcium