Juvenile nasopharyngeal angiofibroma.
JNA is a highly vascular, benign, yet locally invasive tumor that occurs in preadolescent males. Diagnosis is based on history, physical examination, and radiographic findings. CT scanning is invaluable for evaluating tumor extent. Angiography combined with embolization aids surgeons in identifying the main feeding vessels and decreasing intraoperative blood loss. Surgery is the mainstay of therapy with radiation therapy reserved for inoperable masses. For highly aggressive, recurrent angiofibroma, chemotherapy has shown some promise.
D000293:Adolescent; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000175:diagnosis* / Q000628:therapy; D009305:Nasopharynx / Q000000981:diagnostic imaging; D009367:Neoplasm Staging; D011859:Radiography