[Induction of unstable mutations in Drosophila melanogaster by microinjection of DNA from oncogenic viruses into the embryo polar plasma. II. Analysis of the role of injected DNA].
We have demonstrated that the mutagenic effect of oncovirus DNA injected into Drosophila embryos is of two-type locus specificity: the spectrum of mutations induced by the retroviral cDNA (RSV) changed in different recipient stocks and those induced by the adenoviral DNA (Sa7) did not differ in the stocks studied. The Sa7 DNA and the cDNA of RSV induce mutations in different groups of loci. Transpositions of the copia element were found in mutant lines obtained in both cases.
D000256:Adenoviridae / Q000235:genetics*; D000261:Adenoviruses, Simian / Q000235:genetics*; D000818:Animals; D001358:Avian Sarcoma Viruses / Q000235:genetics*; D004251:DNA Transposable Elements; D004279:DNA, Viral / Q000235:genetics*; D004331:Drosophila melanogaster / Q000196:embryology / Q000235:genetics*; D005838:Genotype; D008845:Microinjections; D009154:Mutation; D009693:Nucleic Acid Hybridization; D010063:Ovum; D010957:Plasmids; D012091:Repetitive Sequences, Nucleic Acid
D004251:DNA Transposable Elements; D004279:DNA, Viral
Induktsiia nestabil'nykh mutatsiĭ u Drosophila melanogaster mikroin''ektsieĭ DNK onkogennykh virusov v poliarnuiu plazmu émbrionov. Soobshchenie II. Analiz roli in''etsiruemoĭ DNK.