title: Nanophthalmic uveal effusion.
abstract: A nanophthalmic patient with hypermetropia, shortened anterior-posterior axial length, and thickened choroid presented with a choroidal detachment and nonrhegmatogenous retinal detachment (NRRD). He underwent partial thickness, 5 x 7 mm, sclerectomies and 1-2 mm central sclerostomies 9.5 mm posterior to the limbus, specifically avoiding vortex veins. Complete resolution of the retinal and choroidal detachments occurred in spite of postoperative ultrasonograms demonstrating residual choroidal-scleral thickening. The effectiveness of this technique in our patient, in light of recent studies demonstrating histochemical and microscopic abnormalities in nanophthalmic sclera, suggests impairment of trans-scleral protein transport as the primary pathophysiologic mechanism in nanophthalmic uveal effusion.
mesh_terms: D005122:Exudates and Transudates / Q000378:metabolism*; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008850:Microphthalmos / Q000150:complications* / Q000473:pathology; D008875:Middle Aged; D012163:Retinal Detachment / Q000150:complications; D012599:Sclerostomy; D014463:Ultrasonography; D014603:Uveal Diseases / Q000150:complications* / Q000378:metabolism / Q000601:surgery