title: [Characteristics of the genome of poliovirus type 3 isolated from patients with poliomyelitis in Moldavia].
abstract: Twelve poliovirus isolates of serotype 3 from patients with paralytic poliomyelitis have been analyzed by oligonucleotide mapping of the viral genomes. All the studied strains were isolated from patients in different regions of the Moldavian SSR in 1982. The maps of all isolates are similar but they do not practically possess any large oligonucleotides characteristic of the vaccine strain of type 3 poliovirus. It is concluded that a wild neurovirulent strain of type 3 poliovirus, that circulated in 1982 in the Moldavian SSR was the cause of paralytic poliomyelitis cases. All the studied isolates are suggested to have been derived relatively recently from the common ancestor.
mesh_terms: D004279:DNA, Viral / Q000032:analysis*; D005814:Genes, Viral; D006801:Humans; D008966:Moldova; D009710:Nucleotide Mapping; D009841:Oligonucleotides / Q000032:analysis; D011051:Poliomyelitis / Q000453:epidemiology / Q000382:microbiology* / Q000517:prevention & control; D017955:Poliovirus / Q000235:genetics*; D011054:Poliovirus Vaccine, Inactivated / Q000008:administration & dosage; D012367:RNA, Viral / Q000032:analysis
chemical_list: D004279:DNA, Viral; D009841:Oligonucleotides; D011054:Poliovirus Vaccine, Inactivated; D012367:RNA, Viral
vernacular_title: Kharakteristika genoma shtammov poliovirusa tipa 3, vydelennykh v Moldavii ot bol'nykh poliomielitom.