Rectal transmission of bovine leukemia virus in cattle and sheep.
Bovine leukemia virus (BLV) was transmitted by rectal inoculation of BLV-infective whole blood into cattle and sheep. Two cows and 2 sheep each were given 500 ml and 50 ml of blood, respectively, by rectal infusion. Two sheep which served as positive controls each were given 1 ml of the same blood, IV. All animals became seropositive to BLV by postinoculation week 5. Although relatively large volumes of blood were used for rectal inoculation, a base line for infectivity was established for the rectal route.
D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000635:transmission*; D005260:Female; D001909:Leukemia Virus, Bovine / Q000502:physiology; D007942:Leukemia, Experimental / Q000635:transmission / Q000662:veterinary*; D011897:Random Allocation; D012007:Rectum / Q000382:microbiology*; D012756:Sheep; D012757:Sheep Diseases / Q000635:transmission*