Fixation of experimental osteotomies of the distal femur of rabbits with biodegradable material.
Osteotomies of the distal femur in 19 rabbits were operatively fixed with totally biodegradable implants. Radiographic, histological, microradiographic, and oxytetracycline-labeling studies showing healing of the osteotomy within 6 weeks. The fixation proved stable sufficiently during healing of the osteotomized bone. The osteotomies united without delay and malalignment did not occur, although no external support was used and the rabbits were allowed to walk freely after the operation. Successful use of the biodegradable fixation developed in the present study was reported recently for the treatment of fractures of the ankle.
D000818:Animals; D001672:Biocompatible Materials; D005269:Femur / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D010027:Osteotomy / Q000379:methods; D011100:Polyglycolic Acid / Q000627:therapeutic use*; D019736:Prostheses and Implants; D011817:Rabbits; D011859:Radiography; D013537:Sutures; D014945:Wound Healing
D001672:Biocompatible Materials; D011100:Polyglycolic Acid