An open trial of buspirone in obsessive-compulsive disorder.
Of 14 patients with obsessive-compulsive disorder who entered an 8-week open trial of buspirone, none improved. The ineffectiveness of buspirone may shed light on the serotonergic hypothesis that has been proposed for this disorder.
D000328:Adult; D000553:Ambulatory Care; D002065:Buspirone / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology; D010555:Personality Inventory; D011569:Psychiatric Status Rating Scales; D012701:Serotonin / Q000502:physiology
D012701:Serotonin; D002065:Buspirone