Calmodulin in porcine malignant hyperpyrexia.
The anaesthetic complication malignant hyperpyrexia (MH) is due to an elevation of the myoplasmic Ca2+ concentration. Examination of calmodulin isolated from MH susceptible swine suggests that the disorder in calcium regulation in MH is not due to an abnormality in calmodulin.
D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000037:antagonists & inhibitors / Q000378:metabolism; D000818:Animals; D001923:Brain Chemistry; D002147:Calmodulin / Q000302:isolation & purification* / Q000494:pharmacology; D000242:Cyclic AMP / Q000378:metabolism; D004591:Electrophoresis, Polyacrylamide Gel; D004789:Enzyme Activation / Q000187:drug effects; D006220:Haloperidol / Q000494:pharmacology; D008305:Malignant Hyperthermia / Q000378:metabolism*; D008970:Molecular Weight; D009132:Muscles / Q000378:metabolism; D013056:Spectrophotometry, Ultraviolet; D013552:Swine; D014268:Trifluoperazine / Q000494:pharmacology
D002147:Calmodulin; D014268:Trifluoperazine; D000242:Cyclic AMP; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D006220:Haloperidol