title: [Changes in lipoxygenase activity in developing granulation tissue during aseptic wound healing in rats].
abstract: Activation of lipoxygenases was found during development of granulation tissue in full-layer skin wound simulated in 100 Wistar rats and studied by means of electron paramagnetic resonance and high pressure liquid chromatography. Maximal activation of lipoxygenases within 2 and 6 days corresponded to two phases of wound healing: inflammation phase and phase of fibroblast proliferation during formation of the granulation tissue.
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid; D004578:Electron Spin Resonance Spectroscopy; D004789:Enzyme Activation; D006097:Granulation Tissue / Q000201:enzymology*; D008084:Lipoxygenase / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D014945:Wound Healing
chemical_list: D008084:Lipoxygenase
vernacular_title: Izmenenie aktivnosti lipoksigenaz v oblasti formirovaniia granuliatsionnoĭ tkani pri zazhivlenii asepticheskoĭ rany u krys.