Blister spreading, a diagnostic test in pemphigus. Loss of epidermal and dermoepidermal cohesion.
Differentiation of the pemphigus group of diseases from other bullous dermatoses can be established by spreading of blisters by gentle finger pressure. In combination with histopathology, the same test is diagnostic for every single pemphigus disease.
D000051:Acantholysis / Q000209:etiology; D001485:Basement Membrane / Q000473:pathology; D001706:Biopsy / Q000379:methods; D001768:Blister; D003937:Diagnosis, Differential; D006801:Humans; D010392:Pemphigus / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D011312:Pressure; D012872:Skin Diseases, Vesiculobullous / Q000175:diagnosis