Histochemical changes in the testes of lead induced experimental rats.
The experiments were performed on mature male rats divided in five groups, one control and four experimental in which the animals received 1 mg, 2 mg, 4 mg and 6 mg/kg body weight lead acetate intraperitoneally respectively, over a period of 30 days. ALA-D and lead was estimated in the blood by the use of atomic absorption spectrophotometer and ATP-ase, AMP-ase, Alk-ase were histochemically localized. Significant increase in blood and testis of lead levels along with decrease of ALA-D levels were observed. Changes in the testicular tissue were encountered. Other details concerned with the damage of the testicular tissue are discussed.
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D001485:Basement Membrane / Q000378:metabolism; D006651:Histocytochemistry; D007854:Lead / Q000378:metabolism / Q000633:toxicity*; D008297:Male; D009708:Nucleotidases / Q000378:metabolism; D000623:Porphobilinogen Synthase / Q000378:metabolism; D051381:Rats; D012671:Seminiferous Tubules / Q000378:metabolism; D013737:Testis / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology
D007854:Lead; D009708:Nucleotidases; C018775:adenosine monophosphatase; D000469:Alkaline Phosphatase; D000251:Adenosine Triphosphatases; D000623:Porphobilinogen Synthase