title: Necrotizing fasciitis in a renal transplant patient.
abstract: We have described a 28-year-old diabetic woman who had necrotizing fasciitis of the perineum three years after receiving a living related renal transplant. The diagnosis of necrotizing fasciitis was made early and she was referred to a tertiary care center where she received radical perineal debridement and aggressive medical and surgical follow-up. Necrotizing fasciitis in a transplant patient is rare; review of the literature shows few cases and no survivors. Our patient has returned to a normal life despite continuation of all immunosuppressive therapy throughout the entire hospital course. In addition, she had a good cosmetic result despite the large necrotic perineal infection. Her survival can be attributed to early diagnosis and referral, immediate and extensive debridement, and aggressive protein replacement.
mesh_terms: D000328:Adult; D003646:Debridement; D005208:Fasciitis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery / Q000628:therapy; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D016030:Kidney Transplantation; D009336:Necrosis; D010502:Perineum; D011183:Postoperative Complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery / Q000628:therapy; D012086:Reoperation