[Changes in the nuclear proteinase activity of the liver in gamma-irradiated rats].
Activity of nuclear proteinases in rat liver was studied, by their capacity of splitting a casein substrate, 5-48 h following gamma irradiation. The proteinase activity of nuclei was shown to increase by more than two times in 2-5 h and to decrease by 3-4 times after 15-48 h compared to that of the nonirradiated controls. A sharp decrease in the proteinase activity was also noted in the nuclear matrix of irradiated rat liver.
D000818:Animals; D002364:Caseins / Q000378:metabolism; D002467:Cell Nucleus / Q000201:enzymology / Q000528:radiation effects*; D005720:Gamma Rays; D008099:Liver / Q000201:enzymology / Q000528:radiation effects*; D008297:Male; D010447:Peptide Hydrolases / Q000528:radiation effects*; D051381:Rats; D011919:Rats, Inbred Strains; D013379:Substrate Specificity / Q000528:radiation effects; D013997:Time Factors
D002364:Caseins; D010447:Peptide Hydrolases
Izmenenie proteinaznoĭ aktivnosti iader pecheni gamma-obluchennykh krys.