title: An insect brain peptide as a member of insulin family.
abstract: Amino acid sequencing of bombyxin (previously called 4K-PTTH) isolated from the heads of the silkmoth Bombyx mori has disclosed sequence homology of this insect neuropeptide with insulin. Immunohistochemistry using an antibody against a synthetic bombyxin fragment detected 4 pairs of immunoreactive neurosecretory cells in the dorso-medial region of the Bombyx brain. The same cells were reactive to bovine insulin antibody.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001923:Brain Chemistry; D007301:Insect Hormones / Q000032:analysis*; D007328:Insulin / Q000032:analysis*; D007915:Lepidoptera / Q000032:analysis*; D008969:Molecular Sequence Data; D009036:Moths / Q000032:analysis*
chemical_list: D007301:Insect Hormones; D007328:Insulin; C009089:prothoracicotropic hormone