Amino acid transport systems of lysosomes: possible substitute utility of a surviving transport system for one congenitally defective or absent.
Ways in which other transport systems may compensate for one that is genetically defective are considered. Comparisons of the transport systems of organelles (here the lysosome) with the transport system at the plasma membrane has significant implications for chemotherapy.
D000592:Amino Acid Metabolism, Inborn Errors / Q000628:therapy; D000596:Amino Acids / Q000378:metabolism*; D001692:Biological Transport; D002462:Cell Membrane / Q000378:metabolism; D003553:Cystine / Q000378:metabolism; D006801:Humans; D007425:Intracellular Membranes / Q000378:metabolism; D008247:Lysosomes / Q000378:metabolism*
D000596:Amino Acids; D003553:Cystine