title: [Experimental diabetes in mice infected with Coxsackie viruses].
abstract: The influence of Coxsackie B4 and AI3 viruses on the pancreas of mice (resistant and susceptible to diabetes) was studied. Glucose intolerance and changes in the synthesis of immunoreactive insulin were detected in all the treated groups of animals. Biochemical changes were more prominent in male DBA/2 mice, infected with Coxsackie B4 virus, in FI (CBA X C57Bl/6) hybrids and in female DBA/2 mice infected with Coxsackie AI3 virus and alloxan.
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D003384:Coxsackievirus Infections / Q000097:blood / Q000150:complications*; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000209:etiology*; D004198:Disease Susceptibility; D004770:Enterovirus; D029822:Enterovirus B, Human; D005260:Female; D005951:Glucose Tolerance Test; D007113:Immunity, Innate; D007330:Insulin Antibodies / Q000032:analysis; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D013997:Time Factors
chemical_list: D001786:Blood Glucose; D007330:Insulin Antibodies
vernacular_title: Eksperimental'nyĭ diabet u mysheĭ, infitsirovannykh virusami Koksaki.