title: [Critical comments on reports of fatalities in hereditary fructose intolerance in adulthood from the viewpoint of neuroanesthesia].
abstract: In view of repeated communications in recent years reporting on lethal infusions of fructose or sorbitol in adults with hereditary fructose intolerance, the known statements on the incidence of 1:20,000 are critically analysed. The validity is relativated. The special indication for sorbitol as an osmotherapeutic preparation for lowering intracranial pressure is pointed out. A modified intravenous fructose tolerance test is suggested.
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000601:surgery*; D005632:Fructose / Q000009:adverse effects*; D005633:Fructose Intolerance / Q000235:genetics / Q000401:mortality*; D015318:Fructose Metabolism, Inborn Errors / Q000401:mortality*; D006801:Humans; D007262:Infusions, Intravenous; D012307:Risk Factors; D013012:Sorbitol / Q000009:adverse effects*
chemical_list: D005632:Fructose; D013012:Sorbitol
vernacular_title: Kritische Bemerkungen zu Berichten über Todesfälle durch hereditäre Fructoseintoleranz im Erwachsenenalter aus der Sicht der Neuroanästhesie.