Melanocortins, neural plasticity and aging.
Peptides derived from ACHT and alpha-MSH are known to exert trophic influences on peripheral and central nervous structures. Age-related brain diseases may in part be related to loss of neural plasticity. Melanocortins improve adaptional abilities of the nervous system. Chronic treatment with melanocortins may counteract age-related brain pathology.
D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000375:Aging; D001519:Behavior / Q000187:drug effects; D001921:Brain / Q000502:physiology; D006624:Hippocampus / Q000502:physiology; D006801:Humans; D009074:Melanocyte-Stimulating Hormones / Q000494:pharmacology*; D009416:Nerve Regeneration / Q000187:drug effects; D009473:Neuronal Plasticity / Q000187:drug effects*; D010525:Peripheral Nerves / Q000502:physiology
D000324:Adrenocorticotropic Hormone; D009074:Melanocyte-Stimulating Hormones