Inhibition of human platelet aggregation by motapizone via an increase in intracellular cAMP.
D000241:Adenosine / Q000494:pharmacology; D000818:Animals; D000959:Antihypertensive Agents / Q000494:pharmacology; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism; D000242:Cyclic AMP / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D010208:Papaverine / Q000494:pharmacology; D010974:Platelet Aggregation / Q000187:drug effects*; D011724:Pyridazines / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
D000959:Antihypertensive Agents; D011724:Pyridazines; C051270:motapizone; D010208:Papaverine; D000242:Cyclic AMP; D000241:Adenosine