Towards a selective chemotherapy of virus infections. Development of bromovinyldeoxyuridine as a highly potent and selective antiherpetic drug.
D000818:Animals; D000998:Antiviral Agents / Q000627:therapeutic use*; D001973:Bromodeoxyuridine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use; D002471:Cell Transformation, Neoplastic / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D004259:DNA-Directed DNA Polymerase / Q000378:metabolism; D006566:Herpesviridae Infections / Q000188:drug therapy*; D006801:Humans; D051379:Mice; D013329:Structure-Activity Relationship; D013937:Thymidine Kinase / Q000378:metabolism; D014764:Viral Proteins / Q000378:metabolism
D000998:Antiviral Agents; D014764:Viral Proteins; C020235:brivudine; D013937:Thymidine Kinase; D004259:DNA-Directed DNA Polymerase; D001973:Bromodeoxyuridine