title: Adherence of Campylobacter jejuni and Campylobacter coli to porcine intestinal brush border membranes.
abstract: The adhesion of Campylobacter jejuni and C. coli to isolated porcine intestinal brush border membranes was studied by phase-contrast and electron microscopy. Approximately 45% of the cell population adhered to the brush borders, possibly in a specific manner. Pretreatment of the brush borders with trypsin or pronase, and competitive inhibition with L-rhamnose caused a slight reduction of the adhesion. Different forms of pretreatment of the bacterial cells reduced their ability to adhere, but also their motility.
mesh_terms: D000596:Amino Acids / Q000494:pharmacology; D000606:Amino Sugars / Q000494:pharmacology; D000818:Animals; D001422:Bacterial Adhesion / Q000187:drug effects; D002167:Campylobacter / Q000187:drug effects / Q000502:physiology*; D002168:Campylobacter fetus / Q000187:drug effects / Q000502:physiology*; D002241:Carbohydrates / Q000494:pharmacology; D006801:Humans; D007421:Intestine, Small / Q000187:drug effects / Q000382:microbiology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D008858:Microscopy, Phase-Contrast; D008871:Microvilli / Q000187:drug effects / Q000382:microbiology / Q000648:ultrastructure; D011402:Pronase / Q000494:pharmacology; D013552:Swine; D014357:Trypsin / Q000494:pharmacology
chemical_list: D000596:Amino Acids; D000606:Amino Sugars; D002241:Carbohydrates; D014357:Trypsin; D011402:Pronase