Amyloid fibrils formed from a segment of the pancreatic islet amyloid protein.
A synthetic peptide formed from residues 20-29 of the pancreatic islet amyloid protein has the confirmation of a twisted beta-pleated sheet protein suggesting it is a potential contributor toward amyloid fibril formation in the islets of Langerhans in Type 2 diabetes mellitus.
D000682:Amyloid / Q000032:analysis*; D015740:Calcitonin Gene-Related Peptide; D003924:Diabetes Mellitus, Type 2 / Q000473:pathology; D006801:Humans; D058228:Islet Amyloid Polypeptide; D007515:Islets of Langerhans / Q000032:analysis / Q000473:pathology*; D008854:Microscopy, Electron; D009479:Neuropeptides / Q000032:analysis; D011487:Protein Conformation; D012995:Solubility
D000682:Amyloid; D058228:Islet Amyloid Polypeptide; D009479:Neuropeptides; D015740:Calcitonin Gene-Related Peptide