Results obtained with a sensitive confocal scanning system designed for epifluorescence.
A wide variety of specimens has been examined with our apparatus, a commerical version of which is being manufactured by Bio-Rad/Lasersharp. The advantages expected of a confocal system have been realised in practice, the most striking advantage being the exclusion of glare from out-of-focus structures. This has made it possible to image cytological details in unflattened cells and intact tissues that were previously inaccessible to the light microscope.
D000818:Animals; D004330:Drosophila / Q000235:genetics; D005455:Fluorescent Antibody Technique / Q000295:instrumentation*; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation; D007834:Lasers; D014407:Tumor Cells, Cultured; D014741:Video Recording / Q000295:instrumentation*