title: The role of histamine in the cardiovascular system.
abstract: This article reviews briefly the role of histamine through its H1 and H2 receptors on the cardiovascular system and its action on calcium and catecholamines. The analogy between the adrenergic and the histaminergic systems is well demonstrated and there is evidence that histamine participates in myocardial damage and arrythmias, but the question of its exact role in the early stages of cardiovascular diseases, such as myocardial ischaemia and atherosclerosis, requires further study.
mesh_terms: D000818:Animals; D001161:Arteriosclerosis / Q000209:etiology / Q000378:metabolism; D002118:Calcium / Q000378:metabolism; D002320:Cardiovascular Physiological Phenomena; D002395:Catecholamines / Q000378:metabolism; D003327:Coronary Disease / Q000209:etiology / Q000378:metabolism; D003331:Coronary Vessels; D006632:Histamine / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000378:metabolism; D011969:Receptors, Histamine H1 / Q000378:metabolism; D011970:Receptors, Histamine H2 / Q000378:metabolism
chemical_list: D002395:Catecholamines; D011969:Receptors, Histamine H1; D011970:Receptors, Histamine H2; D006632:Histamine; D002118:Calcium