Parvovirus-induced regression of canine transmissible venereal sarcoma.
In 1981, during the worldwide canine parvovirus (PV) epizootic, canine transmissible venereal sarcomas growing in Beagles in a colony regressed earlier than expected after the dogs became infected with PV. Subsequent studies revealed that modified-live PV vaccine (feline panleukopenia virus) was capable of preventing tumor transplantation when the vaccine was inoculated simultaneously with the tumor in a site distant from the implantation site. However, the PV vaccine had no effect if it was inoculated 3 or 18 days after the tumor was transplanted.
D000818:Animals; D004283:Dog Diseases / Q000382:microbiology* / Q000635:transmission; D004285:Dogs; D005260:Female; D008297:Male; D010322:Parvoviridae Infections / Q000662:veterinary*; D012074:Remission Induction; D012509:Sarcoma / Q000635:transmission / Q000662:veterinary*; D014685:Venereal Tumors, Veterinary / Q000382:microbiology*