Assignment of the prealbumin (PALB) gene (familial amyloidotic polyneuropathy) to human chromosome region 18q11.2-q12.1.
The assignment of the human prealbumin (PALB) gene to chromosome region 18q11-q12.1 has been achieved using a human genomic probe in the study of human-mouse somatic cell hybrids and by in situ hybridization. Because familial amyloidotic polyneuropathy was reported previously to be due to a mutation in prealbumin, it can be inferred that the gene for this disorder also maps to 18q11.2-q12.1.
D000686:Amyloidosis / Q000235:genetics*; D000818:Animals; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002887:Chromosomes, Human, Pair 18; D004247:DNA / Q000235:genetics; D005819:Genetic Markers; D006801:Humans; D006822:Hybrid Cells; D007621:Karyotyping; D051379:Mice; D010523:Peripheral Nervous System Diseases / Q000235:genetics*; D011228:Prealbumin / Q000235:genetics*
D005819:Genetic Markers; D011228:Prealbumin; D004247:DNA