[The protective properties of myelopeptides in the development of infectious processes caused by bacteria of the genus Salmonella].
The protective properties of myelopeptides in the development of bacterial infection in mice and young pigs, caused by S. typhimurium 415, S. cholerae-suis 1422 and 370, have been studied. Myelopeptides have been found to possess protective properties when injected into animals infected with S. typhimurium and S. cholerae-suis in lethal doses. The best protective effect (survival rate of 100%) has been achieved by the injection of myelopeptides 24 hours before challenge. Myelopeptides have also been found to promote the weight gain of young pigs infected with S. cholerae-suis.
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D001853:Bone Marrow / Q000276:immunology*; D004353:Drug Evaluation, Preclinical; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009842:Oligopeptides; D010455:Peptides / Q000627:therapeutic use*; D012481:Salmonella Infections, Animal / Q000401:mortality / Q000517:prevention & control*; D012486:Salmonella typhimurium; D013552:Swine; D013553:Swine Diseases / Q000401:mortality / Q000517:prevention & control; D013997:Time Factors
D009842:Oligopeptides; D010455:Peptides; C048617:myelopeptides
Protektivnye svoĭstva mielopeptidov pri razvitii infektsionnykh protsessov, vyzvannykh bakteriiami roda Salmonella.