Interaction with mitochondria of the anthracycline cytostatics adriamycin and daunomycin.
D000255:Adenosine Triphosphate / Q000378:metabolism; D001692:Biological Transport; D002118:Calcium / Q000378:metabolism; D002455:Cell Division / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D003630:Daunorubicin / Q000378:metabolism / Q000494:pharmacology*; D004317:Doxorubicin / Q000378:metabolism / Q000494:pharmacology*; D004553:Electric Conductivity; D004579:Electron Transport; D005609:Free Radicals; D006863:Hydrogen-Ion Concentration; D008928:Mitochondria / Q000187:drug effects* / Q000502:physiology; D010084:Oxidation-Reduction; D010101:Oxygen Consumption / Q000187:drug effects; D010539:Permeability; D010741:Phospholipases A / Q000502:physiology; D013481:Superoxides / Q000378:metabolism
D005609:Free Radicals; D013481:Superoxides; D004317:Doxorubicin; D000255:Adenosine Triphosphate; D010741:Phospholipases A; D002118:Calcium; D003630:Daunorubicin