Prevalent patterns of serotype-specific seroconversion in Mexican children infected with rotavirus.
The level of neutralizing antibodies to rotaviruses belonging to serotypes 1, 3, and 4 was determined in acute- and convalescent-phase sera from 36 Mexican children with rotaviral diarrhea. Most of the infants who seroconverted fell into one of the following three patterns: single seroconversion to serotype 1; seroconversion to serotypes 1 and 4; or seroconversion to all three serotypes tested. The heterotypic neutralizing antibody responses to rotavirus infections are discussed.
D000914:Antibodies, Viral / Q000032:analysis*; D003967:Diarrhea / Q000276:immunology; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D008800:Mexico; D009500:Neutralization Tests; D012401:Rotavirus / Q000276:immunology*; D012400:Rotavirus Infections / Q000276:immunology*
D000914:Antibodies, Viral