The molecular heterogeneity of protein kinase C and its implications for cellular regulation.
Protein kinase C is now known to be a large family of proteins, with multiple subspecies that have subtle individual enzymological characteristics. Some members of the family exhibit distinct patterns of tissue expression and intracellular localization; different kinases probably have distinct functions in the processing and modulation of a variety of physiological and pathological responses to external signals.
D000595:Amino Acid Sequence; D000818:Animals; D002468:Cell Physiological Phenomena; D005786:Gene Expression Regulation; D007700:Kinetics; D011493:Protein Kinase C / Q000235:genetics / Q000502:physiology*; D014018:Tissue Distribution
D011493:Protein Kinase C