title: [Optimization of combined brachy-teletherapy by the modification technic].
abstract: A method is presented for combined brachy-teletherapy by which the dose distribution of percutaneous irradiation is adapted to the distribution of short-distance irradiation with 192iridium by means of the so-called "field integrated dose modification". Insufficient or excessive doses within the area of superposition of both therapy modalities can so be avoided. Moreover, the therapist can define zones of deviation from the reference dose, if such a dose heterogeneity seems desirable in the individual case. The combined irradiation of prostata and cervix is given as an example to describe in detail the technical, clinical, and radiobiological aspects of this method.
mesh_terms: D001918:Brachytherapy / Q000379:methods / Q000592:standards*; D006801:Humans; D007496:Iridium Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use; D009369:Neoplasms / Q000532:radiotherapy*; D011867:Radioisotope Teletherapy / Q000379:methods / Q000592:standards*; D011879:Radiotherapy Dosage
chemical_list: D007496:Iridium Radioisotopes
vernacular_title: Zur Optimierung der kombinierten Brachy-/Teletherapie mit Hilfe der Modifikationstechnik.