title: Linkage of K99 production and STa activity in a plasmid of an Escherichia coli porcine isolate.
abstract: An Escherichia coli strain ZP118 of porcine origin was shown to harbor a 68-megadalton (Md) plasmid coding for a colonization factor K99 and heat-stable enterotoxin (STa), and a self-transmissible 51-Md plasmid coding for drug resistance. One of the transconjugants obtained by mating between ZP118 and E. coli C was found to harbor a 90-Md plasmid coding for K99, STa and drug resistance. Restriction endonuclease analysis suggested that the 90-Md plasmid could be a recombinant between the 68-Md plasmid and the 51-Md plasmid.
mesh_terms: D000818:Animals; D000954:Antigens, Surface / Q000096:biosynthesis / Q000235:genetics*; D001427:Bacterial Toxins / Q000235:genetics*; D003967:Diarrhea / Q000382:microbiology / Q000662:veterinary; D004768:Enterotoxins / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism; D029968:Escherichia coli Proteins; D010957:Plasmids; D011815:R Factors; D011995:Recombination, Genetic; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology
chemical_list: D000954:Antigens, Surface; D001427:Bacterial Toxins; D004768:Enterotoxins; D029968:Escherichia coli Proteins; C031429:K99 antigen; C034151:heat stable toxin (E coli)