Malignant cystosarcoma phyllodes in a man treated with polyestradiolphosphate. Case report.
Cystosarcoma phyllodes is a rare breast tumor and only five cases have been previously reported in males. A case of cystosarcoma phyllodes in a man treated with polyestradiolphosphate for prostatic carcinoma and by radiation because of breast tenderness is presented. The tumor showed a malignant stroma histologically and the epithelial component was similar to a ductal carcinoma in situ. Electron microscopy revealed several cell types. The possible relationship to radiation and estrogen therapy is discussed.
D000368:Aged; D001943:Breast Neoplasms / Q000139:chemically induced* / Q000473:pathology; D004958:Estradiol / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D008297:Male; D003557:Phyllodes Tumor / Q000139:chemically induced* / Q000473:pathology; D011471:Prostatic Neoplasms / Q000628:therapy
D004958:Estradiol; C008958:polyestradiol phosphate