Localization of brain type creatine kinase in kidney epithelial cell subpopulations in rat.
Immunoperoxidase studies of rat kidney using antibody to brain type isoenzyme of creatine kinase (BB) revealed a specific staining in the epithelial cells of the thick ascending limb of the Henle's loop and collecting tubule. Occasional epithelial cells in cortical tubules that lack brush border were also positive for BB. Renal glomeruli and proximal tubules showed no immunoreactivity to this enzyme.
D000818:Animals; D003402:Creatine Kinase / Q000378:metabolism*; D004848:Epithelium / Q000201:enzymology; D007124:Immunoenzyme Techniques; D007527:Isoenzymes / Q000378:metabolism; D007672:Kidney Cortex / Q000201:enzymology; D007679:Kidney Medulla / Q000201:enzymology; D007684:Kidney Tubules / Q000201:enzymology*; D051381:Rats
D007527:Isoenzymes; D003402:Creatine Kinase