Plasmacytoma growth factor activity of murine granulocyte-macrophage colony-stimulating factor.
Mouse plasmacytoma FLOPC21 was adapted to culture in the presence of a mouse Th cell supernatant. A stable factor-dependent cell line was derived from this culture and the factor responsible for its growth was identified as granulocyte-macrophage colony-stimulating factor.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000502:physiology; D002455:Cell Division / Q000187:drug effects; D003115:Colony-Stimulating Factors / Q000302:isolation & purification / Q000494:pharmacology / Q000502:physiology*; D016178:Granulocyte-Macrophage Colony-Stimulating Factor; D006133:Growth Substances / Q000302:isolation & purification / Q000494:pharmacology / Q000502:physiology*; D015850:Interleukin-6; D007378:Interleukins / Q000276:immunology / Q000302:isolation & purification / Q000502:physiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D010954:Plasmacytoma / Q000473:pathology*; D011994:Recombinant Proteins / Q000494:pharmacology
D000911:Antibodies, Monoclonal; D003115:Colony-Stimulating Factors; D006133:Growth Substances; D015850:Interleukin-6; D007378:Interleukins; D011994:Recombinant Proteins; D016178:Granulocyte-Macrophage Colony-Stimulating Factor