Postoperative radionuclide monitoring of renal allografts on triple therapy.
Renal allograft dysfunction arising from rejection or cyclosporin A nephrotoxicity in patients on high-dose cyclosporin A administration can currently only be distinguished reliably by allograft biopsy excluding rejection. The renographic course up to 35 days after transplantation or to discharge was followed in 30 patients treated with low-dose azathioprine, prednisone, and cyclosporin A (triple therapy). Routine renographic monitoring combined with intravenous angiography in critical periods proved a valuable aid in the differentiation between post-operative complications such as acute rejection and surgical complications.
D001379:Azathioprine / Q000008:administration & dosage; D003524:Cyclosporins / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D006084:Graft Rejection / Q000187:drug effects; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016030:Kidney Transplantation; D011241:Prednisone / Q000008:administration & dosage; D011866:Radioisotope Renography; D011875:Radionuclide Angiography
D003524:Cyclosporins; D007166:Immunosuppressive Agents; D001379:Azathioprine; D011241:Prednisone