[Malakoplakia at 3 sites: the bladder, urethra and kidney. Isolation and ultrastructural study of blood monocytes].
We studied the blood mononuclear cells in a seventy-four-year old man who had urinary tract malacoplakia located to bladder, ureter and kidney. The blood mononuclear cells were isolated as described by Boyum [2] and studied by electron microscopy. They did not show bacilliform bodies or bacteria in the phagolysosomes. The microfilaments and the microtubules were not easily identifiable in the mononuclear cells of the patient. In the control, the internal skeleton of the mononuclear cells was normal. This ultrastructural finding may suggest that there is a relation between microfilaments and microtubules lesion and the low level of cyclic G.M.P. described by Abdou et al.
D008841:Actin Cytoskeleton / Q000648:ultrastructure; D000368:Aged; D002469:Cell Separation; D006152:Cyclic GMP / Q000032:analysis; D006801:Humans; D007674:Kidney Diseases / Q000097:blood* / Q000473:pathology; D008287:Malacoplakia / Q000097:blood* / Q000473:pathology; D008297:Male; D008870:Microtubules / Q000648:ultrastructure; D009000:Monocytes / Q000648:ultrastructure*; D014522:Urethral Diseases / Q000097:blood* / Q000473:pathology; D001745:Urinary Bladder Diseases / Q000097:blood* / Q000473:pathology
D006152:Cyclic GMP
Malacoplasie à triple localisation: vésicale, urétérale et rénale. Isolement et étude ultrastructurale des monocytes sanguins.