Uptake and retention of moulting hormones by the integument of crayfish in vitro. III. The possible involvement of Na+/K+-ATPase.
The specific uptake of the ecdysteroid [3H]ponasterone A into crayfish hypodermis in vitro is inhibited by increasing concentrations of potassium in the medium. The Na+/K+-ATPase blocker ouabain also decreases uptake of the ecdysteroid. Maximal inhibition of uptake is reached at 5 X 10(-5) M ouabain.
D000818:Animals; D003400:Astacoidea / Q000378:metabolism*; D004441:Ecdysterone / Q000031:analogs & derivatives* / Q000378:metabolism; D007700:Kinetics; D010042:Ouabain / Q000494:pharmacology; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*
D004441:Ecdysterone; D010042:Ouabain; C008999:ponasterone A; D000254:Sodium-Potassium-Exchanging ATPase