Occurrence of vanadium ion in serum albumins.
Vanadium was shown to be a contaminant in Sigma-grade serum albumins, fraction V. The levels of vanadium detected by neutron activation analysis were: bovine 16.7, ovine 10.0, rabbit 9.1, porcine 3.9, and human 0.19 micrograms/g protein. According to the ESR spectra, the vanadate form (+5 oxidation state) was strongly suggested as a chemical form present in albumins. Dialysis against a chelating agent was quite effective for removal of the metal ion.
D000818:Animals; D002417:Cattle; D003956:Dialysis; D004578:Electron Spin Resonance Spectroscopy; D006801:Humans; D009501:Neutron Activation Analysis; D011817:Rabbits; D012709:Serum Albumin / Q000032:analysis*; D012710:Serum Albumin, Bovine / Q000032:analysis; D012756:Sheep; D013552:Swine; D014639:Vanadium / Q000032:analysis*
D012709:Serum Albumin; D014639:Vanadium; D012710:Serum Albumin, Bovine