The interaction between fibrinogen and 3H-L-arginine cationic peptides derived from fibrosarcoma in the presence of thrombin.
It has been found that cationic protein breakdown product--3H-L-arginine labelled peptide fraction--interacts with fibrinogen in the presence of thrombin. The formation of the fibrin clot under these conditions makes the clot resistant to the fibrinolytic action of plasmin.
D000818:Animals; D001120:Arginine; D005340:Fibrinogen / Q000378:metabolism*; D005342:Fibrinolysis; D005354:Fibrosarcoma / Q000032:analysis*; D010447:Peptide Hydrolases / Q000378:metabolism; D010455:Peptides / Q000378:metabolism*; D051381:Rats; D013917:Thrombin / Q000494:pharmacology*
D010455:Peptides; D005340:Fibrinogen; D001120:Arginine; D010447:Peptide Hydrolases; D013917:Thrombin