Adult ventricular myocytes isolated from CHF 146 and CHF 147 cardiomyopathic hamsters.
Single ventricular myocytes have been isolated from normal and cardiomyopathic hamsters using a collagenase method. The procedure produces calcium-tolerant myocytes that are viable and appear on light and electron microscopic examination to be healthy. These cells respond to electrical stimulus and have normal intracellular resting and action potentials.
D000200:Action Potentials; D000818:Animals; D002118:Calcium / Q000494:pharmacology; D009202:Cardiomyopathies / Q000473:pathology* / Q000503:physiopathology; D002469:Cell Separation / Q000379:methods*; D006168:Guinea Pigs; D006352:Heart Ventricles / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology; D008564:Membrane Potentials; D003012:Microbial Collagenase; D008854:Microscopy, Electron
D003012:Microbial Collagenase; D002118:Calcium