title: Use of ultrasound for early pregnancy detection in the rhesus and cynomolgus macaque (Macaca mulatta and Macaca fascicularis).
abstract: Diagnostic ultrasound provides an accurate method for the detection of early pregnancy and embryonic loss in macaque species. A developing gestational sac (GS) may be observed on gestational day (GD) 14-15 with positive identification on GD 16-18. Visualization of the yolk sac, embryo, and developing heart on GD 21-25 confirms pregnancy. Continuous observations during embryogenesis provide useful information when assessing the teratogenic potential of a variety of agents.
mesh_terms: D000818:Animals; D005260:Female; D005865:Gestational Age; D008251:Macaca / Q000502:physiology*; D008252:Macaca fascicularis / Q000502:physiology*; D008253:Macaca mulatta / Q000502:physiology*; D011247:Pregnancy; D011270:Pregnancy, Animal; D014463:Ultrasonography / Q000662:veterinary*