Membrane potential of cells and its regulation during aging. 2. Report: the effect of hormones on the level of the cellular plasma membrane polarization.
Age-dependent changes in the polarization of plasma membranes (PM) of various cell types and the mechanisms responsible for its regulation were studied in the experiments on the adult (6-8 and old (28-32 months) Wistar male rats. It was found that the effect of the hormones on the PM polarization level is altered during aging. This being related to shifts in the number and affinity of the hormonal receptors, energetic processes and protein synthesis in the cell.
D000375:Aging / Q000502:physiology*; D000818:Animals; D002084:Butylated Hydroxytoluene / Q000494:pharmacology; D004734:Energy Metabolism / Q000187:drug effects; D006728:Hormones / Q000502:physiology*; D008297:Male; D008564:Membrane Potentials / Q000187:drug effects; D008565:Membrane Proteins / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D011956:Receptors, Cell Surface / Q000502:physiology
D006728:Hormones; D008565:Membrane Proteins; D011956:Receptors, Cell Surface; D002084:Butylated Hydroxytoluene