Musculoskeletal manifestations of systemic lupus erythematosus.
The musculoskeletal system is involved in nearly all patients with SLE. Transient arthralgias or arthritis are common and, in some patients, there is a progression to rheumatoid-like nonerosive hand deformities (Jaccoud's syndrome). The major disabling type of joint disease in lupus is articular osteonecrosis, often induced by high-dose corticosteroids. Rare forms of musculoskeletal manifestations of lupus include spontaneous tendon rupture, crystalline arthropathies, subcutaneous calcifications, and inflammatory myopathy.
D001168:Arthritis / Q000209:etiology; D001847:Bone Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology*; D003460:Crystallization; D006801:Humans; D007592:Joint Diseases / Q000209:etiology; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008279:Magnetic Resonance Imaging; D009135:Muscular Diseases / Q000209:etiology*; D010020:Osteonecrosis / Q000209:etiology; D012422:Rupture, Spontaneous; D013708:Tendon Injuries / Q000209:etiology; D014057:Tomography, X-Ray Computed