title: Exploration of structure-function relationships in human factor VIII by site-directed mutagenesis.
mesh_terms: D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D003001:Cloning, Molecular; D004247:DNA / Q000378:metabolism; D004262:DNA Restriction Enzymes; D005169:Factor VIII / Q000235:genetics* / Q000378:metabolism; D005796:Genes; D006801:Humans; D009154:Mutation; D010957:Plasmids; D011994:Recombinant Proteins / Q000378:metabolism; D013917:Thrombin / Q000378:metabolism
chemical_list: D011994:Recombinant Proteins; D005169:Factor VIII; D004247:DNA; D004262:DNA Restriction Enzymes; D013917:Thrombin