[Magnetic resonance tomography of the heart. Experimental study of a non-invasive characterization of myocardial tissue].
In this experimental study (canine heart) a variety of pathologic conditions of the myocardium were studied using ECG-triggered magnetic resonance imaging (MRI). The purpose of this study was to examine the MR appearance and the T2 relaxation times of occlusive and reperfused myocardial infarcts, of hypertrophic cardiomyopathy, and of cardiac transplants with and without acute cardiac allograft rejection. MR images were correlated with the results of histology and tissue water content. MRI identified normal myocardium with T2 values of 38 (+/- 4.3) msec. Myocardial infarcts and acute allograft rejection had significant (p less than 0.05) longer T2 values compared to normal myocardium. On the basis of T2 relaxation times no further differentiation among different pathologic entities was possible. Therefore, it is necessary to include morphologic criteria such as myocardial wall thickness, cardiac chamber size and intracavitary blood flow signal in the interpretation of cardiac MR tomograms.
D000818:Animals; D002312:Cardiomyopathy, Hypertrophic / Q000473:pathology; D004285:Dogs; D006084:Graft Rejection; D016027:Heart Transplantation; D009682:Magnetic Resonance Spectroscopy; D009203:Myocardial Infarction / Q000473:pathology; D009206:Myocardium / Q000473:pathology*
Magnetische Resonanztomographie (MRT) des Herzens. Experimentelle Studie zur nicht-invasiven Gewebscharakterisierung des Myokards.