Comparison of three rapid methods for detection of antibodies to streptolysin O and DNase B.
Three commercial systems were compared for ability to detect antibodies to streptolysin O (ASO) and DNase B (ADB). Streptozyme (Wampole Laboratories, Cranbury, N.J.) exhibited high sensitivity (100%) for detecting ASO but low sensitivity for ADB (22.2%). The LeapStrep (Organon Teknika, Malvern, Pa.) and Check-Spectra (Diagnostic Technology, Hauppauge, N.Y.) tests had low sensitivities for detecting ASO (35.3 and 21.4%, respectively) and ADB (22.2 and 33.3%, respectively).
D000907:Antibodies, Bacterial / Q000032:analysis*; D000989:Antistreptolysin / Q000032:analysis*; D001426:Bacterial Proteins; D003851:Deoxyribonucleases / Q000276:immunology*; D006386:Hemagglutination Tests; D006801:Humans; D007841:Latex Fixation Tests; D011237:Predictive Value of Tests; D013297:Streptococcus pyogenes / Q000201:enzymology / Q000276:immunology*; D013301:Streptolysins / Q000276:immunology*
D000907:Antibodies, Bacterial; D001426:Bacterial Proteins; D013301:Streptolysins; C025964:streptolysin O; D000989:Antistreptolysin; D003851:Deoxyribonucleases; C020069:deoxyribonuclease B