[Treatment of the acute graft versus host skin reaction with cyclosporin and PUVA].
Acute graft-versus-host reaction is usually managed by immunosuppressive therapy, and cyclosporin is one drug of choice. In some patients, cyclosporin alone cannot always control the evolution. The use of other immunosuppressive drugs could be considered but their toxicity and side-effects are such that a vital risk is introduced for the patient. Conversely, when the disease primarily affects the skin, photochemotherapy (PUVA) associated with cyclosporin appears to be effective and safe.
D000328:Adult; D016026:Bone Marrow Transplantation; D003524:Cyclosporins / Q000627:therapeutic use*; D006087:Graft vs Host Reaction; D006801:Humans; D008297:Male; D011701:PUVA Therapy; D012871:Skin Diseases / Q000188:drug therapy* / Q000473:pathology; D014184:Transplantation, Homologous
D003524:Cyclosporins
Traitement de la réaction cutanée aiguë du greffon contre l'hôte par cyclosporine et PUVA.