Detection of hepatitis A virus in the stools of healthy people from endemic areas.
One-hundred-ninety-two stool samples were tested for the presence of human Hepatitis A antigen. Sixteen of these were also evaluated for the presence of infectious virus. All samples were obtained from young and apparently healthy people from endemic areas for Hepatitis A disease. The isolation of the infectious virus from these stools demonstrates clearly the wide diffusion of the virus in these areas, and its transmission by the oral-fecal route.
D000293:Adolescent; D000328:Adult; D000956:Antigens, Viral / Q000032:analysis; D002478:Cells, Cultured; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D005243:Feces / Q000382:microbiology*; D005455:Fluorescent Antibody Technique; D006506:Hepatitis A / Q000453:epidemiology; D035921:Hepatitis A Antigens; D006507:Hepatovirus / Q000302:isolation & purification*; D006801:Humans; D007558:Italy; D008875:Middle Aged
D000956:Antigens, Viral; D035921:Hepatitis A Antigens