title: [New blood pressure lowering drugs in childhood].
abstract: The treatment by antihypertensive agents has recently been improved by the introduction of angiotensin converting-enzyme inhibitors, and of calcium antagonists, which have been applied successfully in children with acute and chronic hypertension. The converting enzyme inhibitor captopril is used increasingly for the treatment of severe forms of persistent hypertension in children. Side effects from this drug can largely be avoided by using low daily doses. The calcium-antagonist nifedipine can now be regarded as the drug of choice in the treatment of acute elevation of blood pressure in infants and children. For this indication it appears to be superior to other drugs because of its prompt and safe efficacy after sublingual administration.
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D002216:Captopril / Q000627:therapeutic use; D002648:Child; D003981:Diazoxide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers; D002216:Captopril; D003981:Diazoxide
vernacular_title: Neue blutdrucksenkende Medikamente im Kindesalter.