Changes of cAMP and cGMP levels of rat antral and fundic gastric mucosa in different ulcer models.
In both ulcer models investigated, except the 240-min IND and 8-hr STR cAMP values in the antrum, the cyclic nucleotides showed a significant decrease in the gastric mucosa, which is most probably a sign of cellular exhaustion.
D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism*; D006152:Cyclic GMP / Q000378:metabolism*; D004195:Disease Models, Animal; D005260:Female; D005748:Gastric Fundus / Q000378:metabolism; D005753:Gastric Mucosa / Q000378:metabolism*; D007213:Indomethacin; D011706:Pyloric Antrum / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013276:Stomach Ulcer / Q000209:etiology / Q000378:metabolism*; D013312:Stress, Physiological
D000242:Cyclic AMP; D006152:Cyclic GMP; D007213:Indomethacin