title: Rapid healing of diabetic foot ulcers with meticulous blood glucose control.
abstract: Fifteen diabetic patients, with neuropathic food ulcers refractory to conventional treatment, were found to be poorly balanced and were put on meticulous regimens; some on continuous subcutaneous insulin infusion and others on split mixed doses. Once diabetes was controlled, the wound healed rapidly in 11 of the patients within 4 to 13 weeks. In 4 patients amputation was necessary. The outcome was better in patients with good peripheral pulses. We suggest that tight control of diabetes promotes healing of diabetic foot lesions.
mesh_terms: D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000503:physiopathology; D003929:Diabetic Neuropathies / Q000097:blood / Q000503:physiopathology*; D005534:Foot Diseases / Q000503:physiopathology* / Q000628:therapy; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010349:Patient Compliance; D012883:Skin Ulcer / Q000503:physiopathology* / Q000628:therapy; D014945:Wound Healing
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007328:Insulin