title: [Recent possibilities for the treatment of osteoporosis in the aged].
abstract: Treatment of idiopathic osteoporosis in the elderly presupposes exact radiological diagnosis, the exclusion of a primary illness as the cause of the pathological process and exact differential diagnosis from other metabolic osteopathies. We consider possible means of prevention of the immobilization of old people, and appropriate hormonal substitution in cases of previous illnesses which coincide with a disturbance of the gonadal function, as important prophylactic measures. In the case of manifest osteoporosis, if possible, an assignment of the disease to a manifestation with high or low bone turnover should be made, by means of biochemical adjuvants. In high bone turnover, the substitution of sex hormones or the administration of calcitonin is indicated, particularly if symptoms of pain are distinct. In osteoporosis with low bone turnover, fluoride in long-term therapy is the preferred medication. The latest studies show that a combination of fluoride and active vitamin D metabolites is preferable to monotherapy. All therapy for this disease, independent of the age of the patient, should be supported by isometric exercises, analgesics and appropriate dietary measures. Orthopaedic supporting measures should be applied only if conservative measures in acute vertebral fractures fail.
mesh_terms: D000368:Aged; D002118:Calcium / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D045166:Estradiol Congeners / Q000008:administration & dosage; D006801:Humans; D010024:Osteoporosis / Q000188:drug therapy*; D012969:Sodium Fluoride / Q000008:administration & dosage; D014807:Vitamin D / Q000008:administration & dosage
chemical_list: D045166:Estradiol Congeners; D014807:Vitamin D; D012969:Sodium Fluoride; D002118:Calcium
vernacular_title: Neuere Möglichkeiten zur Behandlung der Altersosteoporose.