Preleukemic syndromes and other syndromes predisposing to leukemia.
The myelodysplastic and myeloproliferative syndromes are syndromes in childhood that may precede leukemia. Clinical and biologic features are reviewed in this article. Although rare, they offer an unique opportunity to observe the evolution of leukemia and give clues that are helping us to understand the leukemogenic process.
D002648:Child; D006410:Hematopoiesis; D006801:Humans; D009190:Myelodysplastic Syndromes; D009196:Myeloproliferative Disorders; D011289:Preleukemia; D013577:Syndrome