Reutilization pathway of purine nucleotides in human erythrocytes.
Human erythrocytes can operate the pyrophosphorolysis of IMP and utilize the phosphoribosyl moiety of this compound for the synthesis of AMP and of GMP from exogenous purine bases. Erythrocyte purine phosphoribosyltransferases seem to have a role in this interconversion pathway.
D000249:Adenosine Monophosphate / Q000097:blood; D004912:Erythrocytes / Q000378:metabolism*; D006157:Guanosine Monophosphate / Q000097:blood; D006801:Humans; D066298:In Vitro Techniques; D007291:Inosine Monophosphate / Q000097:blood; D007700:Kinetics; D010430:Pentosyltransferases / Q000097:blood; D011685:Purine Nucleotides / Q000097:blood*
D011685:Purine Nucleotides; D007291:Inosine Monophosphate; D000249:Adenosine Monophosphate; D006157:Guanosine Monophosphate; D010430:Pentosyltransferases; C022484:purine phosphoribosyltransferase