Large granular-cell myoblastoma of the oesophagus.
A granular-cell tumour of the oesophagus, the largest hitherto described, was found in a 44-year-old woman. Histologic examination showed an infiltratively growing granular-cell myoblastoma without pleomorphism or mitotic activity. Local extirpation of the tumour was attempted in order to preserve oesophageal continuity. However, a tracheo-oesophageal fistula and stenosis of the previously tumour-bearing area developed and necessitated nasogastric tube feeding for 18 months. Two attempts to close the fistula, including resection of the fistula-bearing tracheal area, failed. Final cure was achieved by subtotal extirpation of the oesophagus and gastro-oesophageal anastomosis in the neck with the stomach placed retrosternally. Normal intake of food was restored after this operation and 30 months later the patient is doing well.
D000328:Adult; D004938:Esophageal Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D009379:Neoplasms, Muscle Tissue / Q000473:pathology* / Q000648:ultrastructure; D011183:Postoperative Complications / Q000601:surgery; D014138:Tracheoesophageal Fistula / Q000601:surgery