Adrenal scintigraphy in Cushing's syndrome caused by bilateral hyperplasia, adenoma or carcinoma.
The results of scintigraphy in 29 patients with Cushing's syndrome were evaluated. It was possible to separate bilateral hyperplasia from unilateral abnormality. In cases of unilateral abnormality correct localization of the tumour was accomplished and it was possible to visualize adrenocortical carcinoma. The many advantages of adrenal scintigraphy are listed and it is concluded that adrenal scintigraphy is the best means of investigation to differentiate between ACTH-dependent and ACTH-independent Cushing's syndrome.
D015071:19-Iodocholesterol; D000236:Adenoma / Q000150:complications / Q000000981:diagnostic imaging*; D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000000981:diagnostic imaging*; D000311:Adrenal Glands / Q000000981:diagnostic imaging*; D000312:Adrenal Hyperplasia, Congenital / Q000150:complications / Q000000981:diagnostic imaging*; D000324:Adrenocorticotropic Hormone / Q000378:metabolism; D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000150:complications / Q000000981:diagnostic imaging*; D003480:Cushing Syndrome / Q000000981:diagnostic imaging / Q000209:etiology; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging
D007457:Iodine Radioisotopes; D015071:19-Iodocholesterol; D000324:Adrenocorticotropic Hormone