title: S-adenosylmethionine in the treatment of depression.
abstract: The antidepressant property of S-adenosylmethionine (SAMe) has been supported by several uncontrolled and controlled studies. Compared to standard antidepressant agents, SAMe has fewer side-effects and shorter lag period. Future studies to delineate SAMe-responsive depression are warranted.
mesh_terms: D002986:Clinical Trials as Topic; D003866:Depressive Disorder / Q000188:drug therapy*; D006801:Humans; D012436:S-Adenosylmethionine / Q000627:therapeutic use*
chemical_list: D012436:S-Adenosylmethionine