Correction of metabolic acidosis in diarrheal calves by oral administration of electrolyte solutions with or without bicarbonate.
Acid-base balance was evaluated in calves with experimentally induced viral diarrhea. When blood pH decreased to less than 7.200, calves were assigned to treatment groups and fed milk replacer, electrolyte solution without bicarbonate, or electrolyte solution containing bicarbonate. Calves in the electrolyte treatment groups had lower mortality (P less than 0.05), were better hydrated (P less than 0.05), and were less acidotic (P less than 0.05) than calves fed milk replacer. Bicarbonate-containing electrolyte solution restored acid-base balance (P less than 0.05) and corrected depression better (P less than 0.05) than electrolyte solution that did not contain bicarbonate. Both electrolyte solutions were equally good at correcting dehydration.
D000138:Acidosis / Q000209:etiology / Q000628:therapy / Q000662:veterinary*; D000818:Animals; D001639:Bicarbonates / Q000008:administration & dosage / Q000627:therapeutic use*; D001784:Blood Gas Analysis / Q000662:veterinary; D002417:Cattle; D002418:Cattle Diseases / Q000628:therapy*; D003681:Dehydration / Q000628:therapy / Q000662:veterinary; D003967:Diarrhea / Q000150:complications / Q000662:veterinary*; D004573:Electrolytes / Q000008:administration & dosage / Q000627:therapeutic use*; D005440:Fluid Therapy / Q000662:veterinary; D006400:Hematocrit / Q000662:veterinary; D006863:Hydrogen-Ion Concentration; D008297:Male; D008838:Microcomputers; D011897:Random Allocation; D012964:Sodium / Q000008:administration & dosage / Q000627:therapeutic use*; D017693:Sodium Bicarbonate; D012984:Software
D001639:Bicarbonates; D004573:Electrolytes; D017693:Sodium Bicarbonate; D012964:Sodium