Infiltrating orbital granular cell tumour: a case report and literature review.
A surgical biopsy of an infiltrative retrobulbar mass in a 44-year-old man was diagnosed as granular cell tumour. Electron microscopy and immunoperoxidase stains were used to confirm the diagnosis and to study the histogenesis of this rare soft tissue neoplasm. S-100 stain was positive, while neuron-specific enolase and myoglobin stains were negative, suggesting a non-specific neural origin for the cells. The capability of this tumour to invade surrounding tissues has seldom been described in the orbit and is demonstrated by this case.
D000328:Adult; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009379:Neoplasms, Muscle Tissue / Q000000981:diagnostic imaging / Q000648:ultrastructure*; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000648:ultrastructure*; D012983:Soft Tissue Neoplasms / Q000000981:diagnostic imaging / Q000648:ultrastructure*; D014057:Tomography, X-Ray Computed; D014617:Vacuoles / Q000648:ultrastructure