The effect of dibutyryl cAMP on sodium uptake by isolated perfused gills of Callinectes sapidus.
Hemolymph, collected from 25 and 100% seawater acclimated Callinectes sapidus and perfused through the isolated gill, causes increases in Na+ uptake in the gill. Similarly, dibutyryl cAMP causes increases in Na+ uptake when perfused through the gill. Since pericardial organ (PO) extracts dopamine and octopamine are known to increase cAMP levels in the perfused gill, it is suggested that these substances from the PO may be the hemolymph factors which increase Na+ uptake via the mediation of cAMP as second messenger.
D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D003386:Brachyura / Q000378:metabolism*; D003994:Bucladesine / Q000494:pharmacology*; D000242:Cyclic AMP / Q000378:metabolism; D005880:Gills / Q000187:drug effects* / Q000378:metabolism; D006458:Hemolymph / Q000378:metabolism; D009490:Neurosecretory Systems / Q000187:drug effects / Q000378:metabolism; D010477:Perfusion; D012964:Sodium / Q000378:metabolism*; D014882:Water-Electrolyte Balance / Q000187:drug effects
D003994:Bucladesine; D012964:Sodium; D000242:Cyclic AMP