The effects of postmenopausal estrogen therapy on the incidence of arteriosclerotic vascular disease.
Recent studies show that arteriosclerotic cardiovascular disease is associated with high low-density lipoprotein and low high-density lipoprotein cholesterol concentrations and, further, that reversal of these abnormalities can prevent cardiovascular disease. As postmenopausal estrogen therapy favorably changes low-density lipoprotein and high-density lipoprotein cholesterol concentrations, it is hypothesized that reductions in cardiovascular disease will be observed in postmenopausal women so treated. The majority of at least 23 studies support this view.
D001161:Arteriosclerosis / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D004967:Estrogens / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D008593:Menopause / Q000097:blood*; D008875:Middle Aged; D012307:Risk Factors
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D004967:Estrogens; D008055:Lipids