Acetate dialysate versus bicarbonate dialysate: a continuing controversy.
The use of bicarbonate dialysate as the buffer during routine dialysis is growing. This discussion reviews several of the comparative trials in which bicarbonate and acetate buffers have been tested. Effects of the two buffers on BP, cardiac function, and pulmonary performance are discussed. Costs of the two systems are also compared. Patients who seem most likely to benefit from bicarbonate dialysate include those with a reduced muscle mass in whom a high sodium dialysate has not prevented hypotension.
D000085:Acetates / Q000009:adverse effects; D019342:Acetic Acid; D001639:Bicarbonates / Q000009:adverse effects; D002021:Buffers; D006801:Humans; D007022:Hypotension / Q000139:chemically induced; D000860:Hypoxia / Q000139:chemically induced; D009200:Myocardial Contraction / Q000187:drug effects; D006435:Renal Dialysis / Q000009:adverse effects; D012964:Sodium / Q000009:adverse effects; D017693:Sodium Bicarbonate
D000085:Acetates; D001639:Bicarbonates; D002021:Buffers; D017693:Sodium Bicarbonate; D012964:Sodium; D019342:Acetic Acid