Prevalence of antibody to group B (atypical) rotavirus in humans and animals.
Enzyme-linked immunosorbent assays were developed for the detection of group B rotavirus antigen and antibody. The specificities of both assays were evaluated for antigens and serum specific for rotavirus groups A to D. Serum collected in the United Kingdom from different animal species exhibited the following high prevalence of group B rotavirus-specific antibody: pigs, 97%; cattle, 71%; sheep, 91%; and goats, 91%. In human serum, a lower prevalence of group B-specific antibody was detected; serum from blood donors showed 10% prevalence, and serum from veterinarians showed 4% prevalence.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D000956:Antigens, Viral / Q000032:analysis; D002417:Cattle / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D006041:Goats / Q000276:immunology; D006801:Humans; D012401:Rotavirus / Q000276:immunology*; D012756:Sheep / Q000276:immunology; D013552:Swine / Q000276:immunology
D000914:Antibodies, Viral; D000956:Antigens, Viral