[Endothelial morphometry and perforating keratoplasties].
50 corneal grafts were studied by specular microscopy. The endothelial cell morphology of the grafts was analysed by using a computerised image analysis system. The endothelial cell density decreased rapidly during the first three post-operative months (17%). It continued to decrease for the first year (52%, after which cell loss occurred at a slower rate (3% of the sample cell count per year). The coefficient of variation in cell area remained constant (27%). The percentage of endothelial cell loss might be closely associated with the reestablishment of the hexagonal cellular pattern. These results suggest that the endothelium of the graft is in a state of transition during the first year after surgery.
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002452:Cell Count; D002470:Cell Survival; D016039:Corneal Transplantation; D004728:Endothelium, Corneal / Q000473:pathology; D006084:Graft Rejection; D006801:Humans; D006820:Hyaluronic Acid / Q000502:physiology; D008875:Middle Aged; D011184:Postoperative Period; D011379:Prognosis; D012189:Retrospective Studies; D013997:Time Factors
D006820:Hyaluronic Acid
Morphométrie endothéliale et kératoplasties perforantes.