Apparent recurrence of hemolytic uremic syndrome in azathioprine-treated allograft recipients.
The present study describes 3 adult patients with hemolytic uremic syndrome (HUS) leading to chronic renal failure. Following renal transplantation, the 3 patients developed microangiopathic hemolytic anemia associated with acute rejection crises and graft failure. In 2 patients the renal histology of the transplanted kidney was consistent with HUS. It is concluded that, in adult patients, HUS may recur after renal transplantation and contribute to renal graft failure.
D000328:Adult; D001379:Azathioprine / Q000627:therapeutic use*; D005260:Female; D006084:Graft Rejection; D006463:Hemolytic-Uremic Syndrome / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D016030:Kidney Transplantation; D008297:Male; D012008:Recurrence; D006435:Renal Dialysis
D001379:Azathioprine