Spontaneous acute lymphoblastic leukemia in Sprague-Dawley rats. I. Immunogenetic analysis of four individual leukemias.
The antigenic phenotyping of four individual spontaneous ALLs of SD strain revealed practically complete concordance of RT1 class I expression with PBL of SD strain. RT5 antigen as well as class II and SIg markers were not proven. T cell markers defined by MoAbs OX7 (Thy 1.1) and W3/13 (T cell common) were detected on all four ALL tested.
D000818:Animals; D000911:Antibodies, Monoclonal; D000954:Antigens, Surface / Q000032:analysis; D005455:Fluorescent Antibody Technique; D007518:Isoantibodies; D007945:Leukemia, Lymphoid / Q000276:immunology*; D010641:Phenotype; D051381:Rats; D011919:Rats, Inbred Strains; D013601:T-Lymphocytes / Q000145:classification*
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface; D007518:Isoantibodies