title: Immunocytochemical HBsAg evidence in placentas of asymptomatic carrier mothers.
abstract: We report three chronic asymptomatic HBsAg carrier mothers. We studied their placentas via application of the immunohistochemical method to identify HBsAg by peroxidase-antiperoxidase techniques. All three placental specimens showed a positive HBsAg reaction. Due to the strong cytoplasmatic reactivity of the cytotypes, we deduced their active participation in the infection, proving that virosis occurs via transplacental circulation.
mesh_terms: D002353:Carrier State / Q000276:immunology / Q000382:microbiology* / Q000473:pathology; D005260:Female; D006509:Hepatitis B / Q000276:immunology / Q000382:microbiology* / Q000473:pathology / Q000635:transmission; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006801:Humans; D007124:Immunoenzyme Techniques; D010920:Placenta / Q000276:immunology / Q000382:microbiology* / Q000473:pathology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology / Q000382:microbiology* / Q000473:pathology
chemical_list: D006514:Hepatitis B Surface Antigens