Neurosarcoidosis. A report of ten patients illustrating some usual and unusual manifestations.
The common and not so common neurologic lesions due to sarcoidosis include cranial nerve palsies, meningitis, hypothalamic and pituitary lesions, basilar meningitis, polyneuropathy, space occupying lesions and spinal cord involvement. The diagnosis of neurosarcoidosis requires a compatible clinical or radiologic picture of sarcoidosis and histological confirmation of noncaseating granulomas. Serum ACE, Gallium-67 lung scan and bronchoalveolar lavage are of help in supporting the diagnosis and establishing activity of the disease. A CT scan with enhancement is the diagnostic procedure of choice. Corticosteroids are the cornerstone of therapy.
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D002493:Central Nervous System Diseases / Q000188:drug therapy / Q000503:physiopathology; D002648:Child; D003389:Cranial Nerve Diseases / Q000188:drug therapy / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000188:drug therapy / Q000503:physiopathology; D008875:Middle Aged; D009422:Nervous System Diseases / Q000188:drug therapy / Q000503:physiopathology*; D010523:Peripheral Nervous System Diseases / Q000188:drug therapy / Q000503:physiopathology; D012507:Sarcoidosis / Q000188:drug therapy / Q000503:physiopathology*
D000305:Adrenal Cortex Hormones