[Hepatitis caused by cyproheptadine (Periactine). A case and review of the literature].
We report the case of a patient who developed jaundice after receiving cyproheptadine for 29 days. Complete recovery occurred within 3 months after cyproheptadine withdrawal. Analysis of 3 previously reported cases and this observation shows that cyproheptadine-induced hepatitis is uncommon. Hepatitis occurs within the first month of treatment and is of the cytolytic or mixed-pattern type. Jaundice is constant. Most often, recovery occurs quickly after the discontinuation of cyproheptadine. However, acute hepatitis can be followed by prolonged anicteric cholestasis.
D000328:Adult; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D003533:Cyproheptadine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D003533:Cyproheptadine
Hépatite à la cyproheptadine (Périactine). Un cas et revue de la littérature.