title: Placebo response in panic disorder.
abstract: Of 43 patients with panic disorder or agoraphobia with panic attacks who took placebo for 8 weeks in two double-blind studies, one in four markedly improved. Those with consistently normal dexamethasone suppression test results were significantly more likely to show a placebo response as were those with lower anxiety ratings at the outset of treatment.
mesh_terms: D000328:Adult; D000379:Agoraphobia / Q000188:drug therapy; D000525:Alprazolam / Q000627:therapeutic use; D001008:Anxiety Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D002986:Clinical Trials as Topic; D003907:Dexamethasone; D003975:Diazepam / Q000627:therapeutic use; D004311:Double-Blind Method; D005239:Fear; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D010200:Panic; D010919:Placebos / Q000627:therapeutic use*; D011569:Psychiatric Status Rating Scales
chemical_list: D010919:Placebos; D003907:Dexamethasone; D003975:Diazepam; D006854:Hydrocortisone; D000525:Alprazolam