title: Extracolonic manifestations of familial polyposis coli.
abstract: The original concept of familial polyposis coli (FPC) that it is only a genetically determined premalignant disease of the colon changed in the 1950s, with the description of Gardner's syndrome. The extracolonic manifestations of osteoma and epidermoid cyst since have been shown to be only a small part of the spectrum of both benign and malignant extracolonic manifestations of the disease. The modern concept of this condition is that FPC is a genetically determined generalized growth disorder that gives rise to tumors in various parts of the body.
mesh_terms: D011125:Adenomatous Polyposis Coli; D005736:Gardner Syndrome; D006801:Humans; D009378:Neoplasms, Multiple Primary