Cephradine prophylaxis in transurethral procedures for carcinoma of the bladder.
The value of cephradine prophylaxis in reducing urinary infection was assessed in 243 patients undergoing endoscopy for bladder carcinoma. Patients were randomised either to receive 3 peri-operative doses of cephradine or to receive no antibiotic. Urine specimens taken on the fifth post-operative day showed a significantly lower urinary infection rate in those patients receiving cephradine prophylaxis.
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002295:Carcinoma, Transitional Cell / Q000601:surgery; D002511:Cephalosporins / Q000627:therapeutic use*; D002515:Cephradine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003558:Cystoscopy; D006801:Humans; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*; D011292:Premedication; D011446:Prospective Studies; D011897:Random Allocation; D001749:Urinary Bladder Neoplasms / Q000601:surgery*; D014552:Urinary Tract Infections / Q000517:prevention & control*
D002511:Cephalosporins; D002515:Cephradine