title: Biologic effects of chronic ethanol consumption related to a deficient intake of carbohydrates.
abstract: Our present understanding of the many effects of chronic ethanol consumption originated mostly from the use of an experimental model in which animals were maintained on a liquid diet that provided 36% of the total calories as alcohol. Since this diet was considered to be nutritionally adequate, a concept developed that the observed effects were due to the toxicity of alcohol and its metabolites rather than malnutrition. However, several biologic effects can be attributed to a reduced carbohydrate ingestion that accompanies chronic alcohol consumption.
mesh_terms: D000437:Alcoholism / Q000201:enzymology*; D000818:Animals; D004040:Dietary Carbohydrates / Q000008:administration & dosage* / Q000378:metabolism; D004798:Enzymes / Q000378:metabolism; D000431:Ethanol / Q000378:metabolism; D005235:Fatty Liver, Alcoholic / Q000201:enzymology*; D005943:Gluconeogenesis; D005952:Glucose-6-Phosphatase / Q000378:metabolism; D006801:Humans; D008099:Liver / Q000201:enzymology; D009751:Nutritional Requirements
chemical_list: D004040:Dietary Carbohydrates; D004798:Enzymes; D000431:Ethanol; D005952:Glucose-6-Phosphatase