title: Changes in interaction of bovine dentin phosphophoryn with calcium and hydroxyapatite by chemical modifications.
abstract: Dentin phosphophoryn was found to lose its precipitability with calcium ion when dephosphorylated or carboxylate-blocked, whereas precipitation of the intact protein was induced at calcium concentration as low as 2 mM. On the other hand, the adsorption capacity of phosphophoryn onto the hydroxyapatite surface increased when acidic groups were diminished by the above modifications.
mesh_terms: D000327:Adsorption; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002417:Cattle; D011232:Chemical Precipitation; D003804:Dentin / Q000378:metabolism*; D017886:Durapatite; D006882:Hydroxyapatites / Q000378:metabolism*; D010750:Phosphoproteins / Q000302:isolation & purification / Q000378:metabolism*; D011485:Protein Binding
chemical_list: D006882:Hydroxyapatites; D010750:Phosphoproteins; C017630:phosphophoryn; D017886:Durapatite; D002118:Calcium