title: Possible role of galactose-1-P-uridyl transferase activity deficiency in red blood cells in the development of the presenile and senile cataract.
abstract: The activity of red blood cells galactose-1-P-uridyl transferase in 64 patients with presenile and senile cataracts (nondiabetics) and in 41 age-matched controls was investigated. All control subjects examined have shown normal enzymatic levels, while 21.9% of patients with presenile cataracts and 21.7% of patients with senile cataracts presented a statistically significant reduced enzymatic activity (mean +/- 2 SD in controls).
mesh_terms: D000328:Adult; D000368:Aged; D002386:Cataract / Q000201:enzymology* / Q000209:etiology; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D005686:Galactokinase / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D009713:Nucleotidyltransferases / Q000172:deficiency*; D005694:UTP-Hexose-1-Phosphate Uridylyltransferase / Q000097:blood / Q000172:deficiency*
chemical_list: D005686:Galactokinase; D009713:Nucleotidyltransferases; D005694:UTP-Hexose-1-Phosphate Uridylyltransferase