[Clinico-laboratory, immunologic and radionuclide joint indices in psoriatic arthropathy].
A juxtaposition between the clinical-laboratory, immunologic and radionucleotide articular parameters was performed in 50 patients with psoriatic arthropathy, distributed according to the incidence of X-ray manifestations. The late and moderate changes in ESK, leukocytes, fibrinogen, DPA and phosphatasemia do not characterize the severity of the disease. A tendency to hyperuricemia and hypercalcemia is established in the period of arthralgia before the X-ray image for bone-tissue damage. The genetic HLA-B27 predetermination plays a certain role for the more frequent involvement of the spine and sacroiliac joints in the pathological process. The disturbances in the immune system are manifested with increased number of early T-lymphocytes, FcG-receptor lymphocytes, complement (C3b)--receptor lymphocytes and spontaneously blast-transformed cells. The increasing IgG content correlates with the accumulation of macromorphological X-ray images and with the index of mineral metabolism from the articular study with 99MTc-pyrophosphate. The changes in the pertechnetium index for articular vascularization are quantitatively insignificant and do not allow the joining of the psoriatic arthropathy to the group of primary synoviarthritis. The accumulation of technetium pyrophosphate in the articular structures is asymmetric, focal and precedes the changes in the X-ray image.
D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood; D001168:Arthritis / Q000175:diagnosis*; D001798:Blood Proteins / Q000032:analysis; D001799:Blood Sedimentation; D002118:Calcium / Q000097:blood; D011756:Diphosphates; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000175:diagnosis*; D013670:Sodium Pertechnetate Tc 99m; D013601:T-Lymphocytes / Q000276:immunology; D013667:Technetium; D016698:Technetium Tc 99m Pyrophosphate; D014527:Uric Acid / Q000097:blood
D001798:Blood Proteins; D011756:Diphosphates; D014527:Uric Acid; D016698:Technetium Tc 99m Pyrophosphate; D013667:Technetium; D005340:Fibrinogen; D013670:Sodium Pertechnetate Tc 99m; D000469:Alkaline Phosphatase; D002118:Calcium
Kliniko-laboratorni, imunologichni i radionuklidni stavni pokazateli pri psoriatichnata artropatiia.