title: A portrait of the adenosine triphosphate synthetase-hydrolase.
abstract: It is proposed that the ATP-synthetic and ATP-hydrolytic activities of energy-transducing mitochondria, chloroplasts and bacterial membranes are due to different enzyme systems. It is suggested that the alpha-subunits of the oligomycin-sensitive coupling factor catalyze synthesis and the beta-subunits catalyze hydrolysis. Evidence is assembled from the literature in support of this concept.
mesh_terms: D025181:ATP Synthetase Complexes; D000818:Animals; D006868:Hydrolysis; D009097:Multienzyme Complexes / Q000032:analysis* / Q000378:metabolism; D010770:Phosphotransferases / Q000032:analysis* / Q000378:metabolism
chemical_list: D009097:Multienzyme Complexes; D010770:Phosphotransferases; D025181:ATP Synthetase Complexes