A study of three preparations in the treatment of otitis externa.
Twenty-seven patients with an initial diagnosis of otitis externa, untreated for the previous 2 weeks, were treated with weekly aural suction toilet and a choice of three topical drops. Two contained combinations of antibiotics and steroids, one of which also contained an anti-fungal agent. The third was boric acid in spirit. The patients were assessed at weekly intervals until a remission was established. From this study it would appear that antibiotic-based drops confer no real advantage over boric acid in spirit.
D000287:Administration, Topical; D001888:Boric Acids / Q000008:administration & dosage*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004338:Drug Combinations / Q000008:administration & dosage; D004464:Econazole / Q000008:administration & dosage; D005446:Fluocinolone Acetonide / Q000008:administration & dosage*; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage*; D009355:Neomycin / Q000008:administration & dosage*; D010032:Otitis Externa / Q000188:drug therapy*; D011112:Polymyxin B / Q000008:administration & dosage*; D011113:Polymyxins / Q000008:administration & dosage*; D011897:Random Allocation
D001888:Boric Acids; D004338:Drug Combinations; D011113:Polymyxins; C033225:hydrocortisone, neomycin, polymyxin B drug combination; D005446:Fluocinolone Acetonide; D004464:Econazole; D009355:Neomycin; D011112:Polymyxin B; C032688:boric acid; D006854:Hydrocortisone