Hypoplastic tibiae with postaxial polysyndactyly: a new dominant syndrome?
A five year old boy is reported with hypoplastic, bowed tibiae and postaxial polysyndactyly. Sixteen relatives of both sexes in four generations either have bilateral syndactyly or postaxial polydactyly or both. The nature of the condition and the possible mode of inheritance are discussed.
D002675:Child, Preschool; D003241:Consanguinity; D005799:Genes, Dominant; D006801:Humans; D008297:Male; D010375:Pedigree; D011859:Radiography; D013576:Syndactyly / Q000150:complications* / Q000000981:diagnostic imaging; D013977:Tibia / Q000002:abnormalities* / Q000000981:diagnostic imaging