title: [1st results of the diagnosis of focal liver and spleen lesions using gradient echo sequences].
abstract: 15 healthy subjects and 39 patients with focal liver and spleen lesions were examined via MR tomography at 1.5 tesla. Gradient field echos at small angle excitation (less than 90 degrees) were employed. The imaging time per layer was 10 seconds so that rapid imaging could be carried out at respiratory standstill. This enabled visualisation of liver and spleen without interference by breathing artifacts and with accurate localisation. Focal lesions can be imaged best at low flip-angle pulses (liver) or low to medium-angle pulses (spleen). The primary liver cell carcinoma is visualised as an inhomogeneous structure with similar signal intensity as the surrounding tissue. All other examined liver lesions (metastases, haemangiomas, lymphatic infiltrates, echinococcus cysts, FNH, gummae) showed greater signal intensity than the remaining organ at small angle excitation. Furthermore, contrast reversals were seen at medium-angle pulses. Contrariwise, with the exception of the light-coloured spleen infarcts, spleen lesions (lymphatic infiltrate, Boeck's disease or sarcoidosis) appeared darker at all excitation angles than the surrounding tissue.
mesh_terms: D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D013158:Splenic Diseases / Q000175:diagnosis*
vernacular_title: Erste Ergebnisse in der Diagnostik fokaler Leber- und Milzläsionen mittels Gradientenechosequenzen.