title: Bone metabolism in patients with rheumatoid arthritis.
abstract: Bone metabolism in patients with rheumatoid arthritis is reviewed. Two different entities are recognised: 1) a localised periarticular bone loss, due to inflammatory processes and 2) a generalised increased bone turnover, ultimately leading to a loss of axial bone mass. The mechanism of this loss of axial bone is not completely understood; probably immobilisation is the most important factor. The influence of certain drugs is discussed.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000009:adverse effects; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism*; D001851:Bone Diseases, Metabolic / Q000209:etiology; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D007592:Joint Diseases / Q000209:etiology; D009068:Movement; D011859:Radiography; D012307:Risk Factors
chemical_list: D000305:Adrenal Cortex Hormones