title: In vivo and in vitro ultrasound beam distortion measurements of a large aperture and a conventional aperture focussed transducer.
abstract: Ultrasound focussing through human tissue of thicknesses varying from 10 mm to 35 mm has been measured for two transducers with diameters 50 mm and 19 mm both focussed at 50 mm (f/1 and f/2.6, respectively). Comparisons are made between the two-way focal depth beam patterns obtained in water and those obtained after passage through tissue to study the degrading effects of frequency-dependent attenuation and inhomogeneities, and their dependence on aperture size. The effects of frequency-dependent attenuation is to broaden the beam and shorten the focal distance. Inhomogeneities mainly increase the sidelobe levels and cause deviations from the central beam axis. A direct comparison of the beam patterns of the two transducers after passage through the same tissue samples shows that the resolution is improved by using the larger aperture. The use of the larger transducer in the in vitro measurements on three human liver specimens demonstrated an average improvement in the -6 dB beamwidth, over the smaller transducer, of 42% (standard deviation +/- 3%). The average improvement in the in vivo measurements on ten female breasts was 34% (standard deviation +/- 5%). The measured improvement in water was 52%. Therefore, the measured resolution improvement in tissue is approximately 2/3 of that obtained in water. The results indicate that for an f/1 transducer with a focal depth of 50 mm the upper limit of maximum useful aperture size has not been reached.
mesh_terms: D000818:Animals; D001940:Breast / Q000033:anatomy & histology; D002417:Cattle; D005260:Female; D006801:Humans; D008099:Liver / Q000033:anatomy & histology; D008954:Models, Biological; D011312:Pressure; D014159:Transducers; D014465:Ultrasonics; D014463:Ultrasonography / Q000295:instrumentation* / Q000379:methods; D014867:Water
chemical_list: D014867:Water