Demonstration of IgE-sensitized mast cells in human heart and kidney.
We report the direct demonstration of IgE-bearing mast cells in human heart and kidney, as shown by immunohistochemical methods. This finding lends further support to the role of mast cells and IgE in the direct involvement of these two organs in immediate-type allergic reactions.
D006801:Humans; D006967:Hypersensitivity / Q000276:immunology; D007124:Immunoenzyme Techniques; D007073:Immunoglobulin E / Q000276:immunology; D007668:Kidney / Q000166:cytology / Q000276:immunology*; D008407:Mast Cells / Q000276:immunology*; D009206:Myocardium / Q000166:cytology / Q000276:immunology*
D007073:Immunoglobulin E