Interception. IV: Failure of mifepristone (RU 486) as a monthly contragestive, "Lunarette".
The new antiprogestin mifepristone (RU 486) was studied as a contragestive for continuous fertility control in 24 menstrual cycles. Two pregnancies out of three conceptions continued in spite of antiprogestin treatment. To date, mifepristone at the doses used appears to be inadequate for monthly use.
D003281:Contraceptives, Postcoital; D004334:Drug Administration Schedule; D010064:Embryo Implantation / Q000187:drug effects; D004963:Estrenes / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008183:Luteal Phase / Q000187:drug effects; D008600:Menstruation-Inducing Agents; D015735:Mifepristone; D010865:Pilot Projects; D011247:Pregnancy
D003281:Contraceptives, Postcoital; D004963:Estrenes; D008600:Menstruation-Inducing Agents; D015735:Mifepristone