What is the effect of a cytomegalovirus infection when superimposed on HBsAg-positive chronic hepatitis?
A non-transfusion-related cytomegalovirus infection was observed in two patients with chronic HBsAg-positive liver disease. Both patients were immunodepressed and died of acute hepatic failure. A superimposed CMV infection has a high fatality rate in the case of underlying chronic type B liver disease.
D000328:Adult; D000954:Antigens, Surface / Q000032:analysis; D002452:Cell Count; D002908:Chronic Disease; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000276:immunology; D006509:Hepatitis B / Q000150:complications* / Q000276:immunology; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000032:analysis; D008297:Male; D013601:T-Lymphocytes / Q000276:immunology
D000954:Antigens, Surface; D006514:Hepatitis B Surface Antigens; D007136:Immunoglobulins