title: [Radiation therapy of nasopharyngeal carcinoma. Retrospective study for the assessment of long-term results].
abstract: During the years from 1967 to 1986, 90 patients with nasopharyngeal carcinomas were irradiated at the Radiologic Hospital of Bonn University. The median overall survival time was 4.3 years which corresponded to 23% of the statistical life expectancy of the patients. 66% were still alive after two years and 46.5% after five years. Compared to the overall group, the prognosis was significantly worse in case of highly differentiated, keratinizing squamous cell carcinomas, penetration of the primary tumor into the base of the skull, or certain symptoms as ophthalmo-neurologic troubles, headaches, loss of body weight, night sweat, or fever. After partial tumor excision performed prior to irradiation or complete remission following to radiotherapy, the therapy results were better than the average with median survival times of about eleven years.
mesh_terms: D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D006801:Humans; D009303:Nasopharyngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D011867:Radioisotope Teletherapy; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
chemical_list: D003037:Cobalt Radioisotopes
vernacular_title: Strahlentherapie des Nasopharynxkarzinoms. Folgestudie zur Beurteilung der Langzeitergebnisse.