title: Efficacy of vaccination with Skinner vaccine towards the prevention of herpes simplex virus induced cervical carcinoma in an experimental mouse model.
abstract: The incidence of cervical carcinoma, which had been induced by vaginal application of inactivated herpes simplex virus type 2 (HSV-2) with 20% croton oil, was significantly reduced in mice prevaccinated with the Skinner herpes vaccine. There was evidence of an immunological response in both vaccinated and unvaccinated mice.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis; D003436:Croton Oil / Q000633:toxicity; D005260:Female; D006558:Herpes Genitalis / Q000150:complications / Q000517:prevention & control*; D051379:Mice; D018139:Simplexvirus / Q000276:immunology*; D002583:Uterine Cervical Neoplasms / Q000209:etiology / Q000473:pathology / Q000517:prevention & control*; D014765:Viral Vaccines / Q000627:therapeutic use*
chemical_list: D000914:Antibodies, Viral; D014765:Viral Vaccines; D003436:Croton Oil