Chimeric multispecific DNA methyltransferases with novel combinations of target recognition.
DNA target recognizing domains of different multispecific DNA-cytosine-methyltransferases can be rearranged through engineering of the corresponding genes to generate enzymes with novel combinations of target recognition.
D004248:DNA (Cytosine-5-)-Methyltransferases / Q000502:physiology*; D004252:DNA Mutational Analysis; D004268:DNA-Binding Proteins / Q000502:physiology; D004926:Escherichia coli / Q000201:enzymology; D010957:Plasmids; D011994:Recombinant Proteins; D013329:Structure-Activity Relationship; D013379:Substrate Specificity
D004268:DNA-Binding Proteins; D011994:Recombinant Proteins; D004248:DNA (Cytosine-5-)-Methyltransferases