Perilesional linear atrophy and hypopigmentation after intralesional corticosteroid therapy. Report of two cases and review of the literature.
We report on the cases of two patients in whom linear perilesional hypopigmentation and atrophy developed after intralesional injection of corticosteroids for treatment of keloids. Evaluation of our patients and the previously reported cases showed that perilesional linear atrophy or hypopigmentation (or both) is a distinct complication after intralesional or intraarticular administration of corticosteroids and is probably due to lymphogenous spread of the steroid suspension.
D001284:Atrophy / Q000139:chemically induced; D001706:Biopsy; D002648:Child; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007627:Keloid / Q000188:drug therapy*; D008297:Male; D010859:Pigmentation Disorders / Q000139:chemically induced*; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D014221:Triamcinolone / Q000009:adverse effects
D005938:Glucocorticoids; D014221:Triamcinolone