Congenital anaplastic astrocytoma with favorable prognosis. Case report.
A large intracranial tumor that caused macrocrania leading to dystocia was demonstrated by prenatal ultrasound examination. After birth, computerized tomography (CT) confirmed the presence of a giant supratentorial tumor with a large cyst. When the infant was 20 days old, the tumor was radically extirpated. Neuropathological examination revealed an astrocytoma with focal signs of anaplasia showing a macrocyst as well as multiple microcysts resulting from hemorrhages into the tumor. Although no adjuvant radio- or chemotherapy was administered, the child had nearly normal psychomotor development without clinical or CT evidence of tumor recurrence, and is now 3 years old.
D001254:Astrocytoma / Q000151:congenital* / Q000473:pathology / Q000601:surgery; D001932:Brain Neoplasms / Q000151:congenital* / Q000473:pathology / Q000601:surgery; D002557:Cerebrospinal Fluid Shunts; D006801:Humans; D006849:Hydrocephalus / Q000150:complications / Q000601:surgery; D007150:Immunohistochemistry; D007231:Infant, Newborn; D008297:Male; D011296:Prenatal Diagnosis; D011379:Prognosis; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography