title: [Investigations on the tissue compatibility of silicon rubber materials using experimental animals].
abstract: The reaction of subcutaneous tissue in guinea-pigs at implants of six kinds of silicone rubber materials (VEB Chemiewerk Nünchritz) was investigated by semiquantitative and quantitative methods. These based on the "Programme to the Assessment of Subcutaneous Tissue Reactions at Implants" by Knöfler, Keller etc. The histocompatibility of the tested materials can be compared with that of titanium. One of the silicone rubbers differs from both the reference material and the other silicone rubber materials significantly and is assessed to be more suitable than the alloy Gisadent KCM 83 (chromium cobalt molybdenum alloy).
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D005549:Foreign-Body Reaction / Q000473:pathology; D006168:Guinea Pigs; D008422:Materials Testing; D012828:Silicones; D012867:Skin / Q000473:pathology; D013329:Structure-Activity Relationship; D013997:Time Factors
chemical_list: D001672:Biocompatible Materials; D012828:Silicones
vernacular_title: Tierexperimentelle Untersuchungen zur Gewebeverträglichkeit von Silikonkunststoffen.