title: [Immunoenzyme method for demonstrating the antigen and antibodies to the human immunodeficiency virus and its use for the serological examination of different population groups].
abstract: An enzyme immune diagnosticum for the detection of the antigen and antibody to human immunodeficiency virus (HIV) has been developed at D. I. Ivanovskiĭ Institute of Virology of the USSR AMS. The method is based on the principle of competitive analysis using an antiviral conjugate which allows the sera to be tested without preliminary dilution and ensures a high sensitivity of the diagnosticum. The survey for HIV antibody covered 5743 subjects, among them 4898 Soviet citizens predominantly belonging to high risk groups of contracting AIDS infection, and 845 foreigners. No antibody to HIV has been detected in any of the Soviet citizens. Among the foreigners, antibody to HIV were detected in 6 subjects, all of them arriving from different African countries.
mesh_terms: D015492:AIDS Serodiagnosis / Q000379:methods*; D000163:Acquired Immunodeficiency Syndrome / Q000517:prevention & control*; D000349:Africa / Q000208:ethnology; D005069:Evaluation Studies as Topic; D015483:HIV Antibodies / Q000032:analysis*; D015488:HIV Antigens / Q000032:analysis*; D006801:Humans; D007124:Immunoenzyme Techniques; D008403:Mass Screening / Q000379:methods*; D011933:Reagent Kits, Diagnostic; D012307:Risk Factors; D014586:USSR
chemical_list: D015483:HIV Antibodies; D015488:HIV Antigens; D011933:Reagent Kits, Diagnostic
vernacular_title: Immunofermentnyĭ metod indikatsii antigena i antitel k virusu immunodefitsita cheloveka i ego ispol'zovanie dlia serologicheskogo obsledovaniia razlichnykh grupp naseleniia.