Cytomegalovirus encephalitis associated with episodic neurologic deficits and OKT-8+ pleocytosis.
After 3 days of symptoms suggesting a viral illness, a 35-year-old man experienced three episodes of aphasia, right-sided sensory symptoms, and bifrontal headache. Each lasted several hours. CSF examination revealed a moderate lymphocytosis consisting of 80% OKT-8+ cells. Serum anti-cytomegalovirus (anti-CMV) antibody titer was elevated at 1:1,024 and subsequently fell to 1:64. Episodic symptoms recurred 5 months later, at which time the anti-CMV titer peaked at 1:8,192. A trial of inhaled oxygen aborted two episodes after several minutes each.
D000328:Adult; D003586:Cytomegalovirus Infections / Q000134:cerebrospinal fluid / Q000503:physiopathology*; D004569:Electroencephalography; D004660:Encephalitis / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D008218:Lymphocytosis / Q000209:etiology; D008297:Male; D010100:Oxygen / Q000627:therapeutic use; D011433:Propranolol / Q000627:therapeutic use
D011433:Propranolol; D010100:Oxygen