Role of bile acids and neutral sterols in carcinogenesis.
Epidemiological evidence regarding cancer causation suggests the existence of a strong link to diet-related lifestyles. Neutral sterols and bile acids constitute a group of metabolic endproducts known to have multiple interactions both from the standpoint of being influenced by diet as well as from the standpoint of their role in cellular and molecular processes relating to carcinogenesis. Epidemiological and experimental studies on the possible role of these steroid metabolites are reviewed.
D000818:Animals; D001647:Bile Acids and Salts / Q000378:metabolism*; D004032:Diet; D006801:Humans; D008019:Life Style; D009369:Neoplasms / Q000139:chemically induced*; D013261:Sterols / Q000378:metabolism*
D001647:Bile Acids and Salts; D013261:Sterols