title: 201Tl/67Ga uptake ratio in small cell carcinoma of the lung: with special reference to serum neuron-specific enolase and prognosis.
abstract: 201Tl/67Ga crude uptake ratio (CUR) was measured in 12 patients with small cell carcinoma of the lung (SCCL); it was further compared with serum neuron-specific enolase (NSE) and the actual survival times. A significant inverse correlation was observed between CUR and serum NSE (r = 0.610; p less than 0.05); CUR also correlated with actual survival time (r = 0.605; p less than 0.05). Oat cell-type SCCL having a low CUR and highly raised serum NSE, showed a poorer prognosis than the other subtype which has a high CUR whose serum NSE was not raised as much as in oat cell-type SCCL. This preliminary study suggests that 201Tl/67Ga uptake ratio is a possible prognostic indicator of SCCL.
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000000981:diagnostic imaging; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018288:Carcinoma, Small Cell / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000000981:diagnostic imaging; D004796:Clinical Enzyme Tests; D003937:Diagnosis, Differential; D005260:Female; D005710:Gallium Radioisotopes; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010751:Phosphopyruvate Hydratase / Q000097:blood*; D011379:Prognosis; D011868:Radioisotopes; D011877:Radionuclide Imaging; D013793:Thallium
chemical_list: D005710:Gallium Radioisotopes; D011868:Radioisotopes; D013793:Thallium; D010751:Phosphopyruvate Hydratase