[Precursor cells of newly formed connective tissue in inflammatory foci in various organs in mice].
The origin of fibroblast-like cells of the capsule around a foreign body in the spleen, liver, peritoneal cavity, subcutaneous connective tissue of mice, the localization of cells-precursors, their proliferative potencies and the ability to migrate through blood were studied using 3H-thymidine autoradiography. Precursors of the inflammation focus cells (irrespective of localization) reproduce intensively outside the limits of intraorganic connective tissue, supposedly, in hemopoietic organs of the bone marrow type and migrate, through the blood channel, into tissues (inflammation foci), where they terminate their differentiation.
D000818:Animals; D001345:Autoradiography; D002454:Cell Differentiation; D002455:Cell Division; D002465:Cell Movement; D003238:Connective Tissue / Q000473:pathology*; D003240:Connective Tissue Diseases / Q000473:pathology*; D005347:Fibroblasts / Q000473:pathology; D005549:Foreign-Body Reaction / Q000473:pathology; D007249:Inflammation / Q000473:pathology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D013234:Stem Cells / Q000473:pathology*; D013997:Time Factors
Kletki-predshestvenniki novoobrazovannoĭ soedinitel'noĭ tkani ochagov vospaleniia v raznykh organakh mysheĭ.