title: [Protective properties of microcrystalline cellulose in experimental diabetes mellitus in rats].
abstract: The experiments on 45 inbred male and female rats with alloxan diabetes have shown that microcrystalline cellulose at a dose of 3 g/day received per os beginning from day 15 to day 42 after alloxan administration stabilizes the animals' body mass, reduces the level of glycemia and glycosylated hemoglobin. A parallel reduction of triglyceride and total cholesterol levels and increase in plasma phospholipid content, compared to the control, are observed, as well as a considerable hypocoagulation shift in the blood aggregation system.
mesh_terms: D000818:Animals; D001777:Blood Coagulation; D001786:Blood Glucose / Q000032:analysis; D001835:Body Weight; D003460:Crystallization; D003921:Diabetes Mellitus, Experimental / Q000178:diet therapy* / Q000378:metabolism; D004043:Dietary Fiber / Q000627:therapeutic use*; D004353:Drug Evaluation, Preclinical; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism; D051381:Rats
chemical_list: D001786:Blood Glucose; D004043:Dietary Fiber
vernacular_title: Zashchitnye svoĭstva mikrokristallicheskoĭ tselliulozy pri éksperimental'nom sakharnom diabete u krys.