Intracranial catecholamine secreting paragangliomas.
Three intracranial catecholamine-secreting paragangliomas are described. They involved a glomus jugulare, a sphenopalatine ganglion and the clivus and upper cervical spine respectively. The extent of the tumours was shown by CT and MRI. They were all highly vascular with a substantial blood supply from systemic arteries which was subjected to particulate embolisation, followed in two cases by surgery. The importance of studying any tumour which could possibly be a paraganglioma for hormonal and, especially, for catecholamine secretion prior to any invasive procedure, including angiography and embolisation, is emphasised: all such procedures should be covered with catecholamine blocking agents and, in addition, carefully monitored with resuscitation facilities immediately available.
D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis / Q000378:metabolism* / Q000628:therapy; D002345:Carotid Body Tumor / Q000175:diagnosis / Q000378:metabolism* / Q000628:therapy; D002395:Catecholamines / Q000378:metabolism*; D002533:Cerebral Angiography; D004621:Embolization, Therapeutic; D005260:Female; D005925:Glomus Jugulare Tumor / Q000175:diagnosis / Q000378:metabolism* / Q000628:therapy; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D010235:Paraganglioma / Q000175:diagnosis / Q000378:metabolism* / Q000628:therapy; D010236:Paraganglioma, Extra-Adrenal / Q000378:metabolism*; D014057:Tomography, X-Ray Computed
D002395:Catecholamines