Activation of the CNS noradrenergic system may inhibit as well as facilitate pituitary luteinizing hormone release.
Earlier work established that neural secretion of luteinizing hormone-releasing hormone (LH-RH) and the resultant release of pituitary gonadotropins could be facilitated by activating alpha-receptors of a central noradrenergic (NA) system. The present study emphasizes that central NA mechanisms may also inhibit LH release largely through activation of beta-adrenergic receptors.
D000818:Animals; D001921:Brain / Q000502:physiology; D005625:Frontal Lobe / Q000502:physiology; D007031:Hypothalamus / Q000502:physiology*; D007986:Luteinizing Hormone / Q000378:metabolism*; D009433:Neural Inhibition; D009638:Norepinephrine / Q000502:physiology*; D051381:Rats; D011943:Receptors, Adrenergic, beta / Q000187:drug effects / Q000502:physiology*; D013565:Sympatholytics / Q000494:pharmacology; D013566:Sympathomimetics / Q000494:pharmacology
D011943:Receptors, Adrenergic, beta; D013565:Sympatholytics; D013566:Sympathomimetics; D007986:Luteinizing Hormone; D009638:Norepinephrine