[Effect of gamma radiation on the components of hepatitis B virus and the delta antigen].
The influence of ionizing irradiation on the serological activity of purified HBsAg, receptors to polymerized albumin, DNA-polymerase activity, delta agent, and delta antigen was studied. Different radiosensitivity of hepatitis B virus components and delta-system was demonstrated. The possibility of sterilization by irradiation of purified HBsAg preparations suitable for construction of a vaccine against hepatitis B was shown.
D004259:DNA-Directed DNA Polymerase / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D006511:Hepatitis B Antigens / Q000528:radiation effects*; D006514:Hepatitis B Surface Antigens / Q000302:isolation & purification / Q000528:radiation effects; D006515:Hepatitis B virus / Q000201:enzymology / Q000276:immunology / Q000528:radiation effects*; D003698:Hepatitis Delta Virus / Q000276:immunology / Q000528:radiation effects*; D017457:Receptors, Albumin; D011946:Receptors, Antigen / Q000528:radiation effects; D011956:Receptors, Cell Surface / Q000528:radiation effects; D013242:Sterilization / Q000379:methods
D006511:Hepatitis B Antigens; D006514:Hepatitis B Surface Antigens; D017457:Receptors, Albumin; D011946:Receptors, Antigen; D011956:Receptors, Cell Surface; C030500:hepatitis B surface antigen receptor; D004259:DNA-Directed DNA Polymerase
Vliianie gamma-izlucheniia na komponenty virusa gepatitia B i del'ta-antigen.