Effects on fertility of rabbits after active immunization with rat testicular cytochrome ct.
A Male rabbit was immunized with rat testicular cytochrome (Cyt) ct and mated with normal, unimmunized females. The matings resulted in abnormal pregnancies: no offspring or stillborn or undersized liveborn offspring weighing 25-30 gm each. Another unusual observation was that fur-pulling behavior, normally exhibited by pregnant female rabbits at the end of the gestational period, was absent in all of these pregnancies. Therefore, immunization of a normal rabbit with testicular cyt ct appeared to interfere with physiological and behavioral aspects of pregnancy in normal female rabbits. The immunological basis of these findings remains to be determined.
D000818:Animals; D001522:Behavior, Animal; D003574:Cytochrome c Group / Q000276:immunology*; D005260:Female; D005298:Fertility; D007114:Immunization; D007248:Infertility, Male / Q000209:etiology; D008297:Male; D011247:Pregnancy; D011817:Rabbits; D051381:Rats; D013737:Testis / Q000201:enzymology* / Q000276:immunology
D003574:Cytochrome c Group