Associations between a fluorescent DNA ligand, 4',6-diamidine-2-phenylindole.2HCl (DAPI), and RNA.
The experiments performed in vitro have shown that DAPI and RNA form insoluble and indigestible complexes. This seems to explain the earlier observed retardation of drug accumulation in the nucleus of a living cell in the presence of RNA.
D004247:DNA / Q000378:metabolism*; D005456:Fluorescent Dyes; D007211:Indoles / Q000378:metabolism*; D008024:Ligands; D012260:Ribonucleases; D012441:Saccharomyces cerevisiae; D013056:Spectrophotometry, Ultraviolet
D005456:Fluorescent Dyes; D007211:Indoles; D008024:Ligands; C007293:DAPI; D004247:DNA; D012260:Ribonucleases