title: Effect of dietary supplements of sodium or potassium bicarbonate on short-term macromineral balance in swine.
abstract: Four crossbred barrows, weighing an average of 26 kg each, were fitted with simple T-cannulas in the terminal ileum and placed in metabolism cages to evaluate the effect of dietary supplements of NaHCO3 or KHCO3 on the short-term metabolism of sodium (Na), potassium (K), calcium (Ca), magnesium (Mg) and chloride (Cl). A control diet containing 2.8 g/kg Na and 4.1 g/kg K was compared with similar diets supplemented with either 13 g/kg or 26 g/kg NaHCO3 or 30 g/kg KHCO3. All diets contained 4 g/kg Cr2O3 as an external marker and were offered twice daily (1,100 g X pig-1 X d-1) in a 4 X 4 Latin square arrangement. Feces and total urine output were collected for 24 h on the fifth day after introducing a new diet; digesta was collected for 12-h periods on d 6 and 7. Sodium and K concentrations at the terminal ileum were unaffected by dietary treatment. Apparent ileal digestibility of Na was increased by NaHCO3 supplements. Over the total gastrointestinal tract, diet had no affect on apparent Na digestibility. Urinary Na clearance was increased by NaHCO3 in the diet in a dose-dependent manner. Net Na retention (g/d) was increased by NaHCO3. Apparent ileal digestibility of K was increased by KHCO3. Apparent fecal digestibility of K was increased by KHCO3 and NaHCO3. Urinary K clearance was elevated by KHCO3, but not enough to overcome the increased K intake; net K balance (g/d) rose in response to dietary KHCO3 supplements. Sodium bicarbonate or KHCO3 had no effect on short-term digestibility or balance of Mg, Ca or Cl.(ABSTRACT TRUNCATED AT 250 WORDS)
mesh_terms: D000818:Animals; D001639:Bicarbonates / Q000494:pharmacology*; D002118:Calcium / Q000378:metabolism*; D002712:Chlorides / Q000378:metabolism*; D006706:Homeostasis / Q000187:drug effects; D008274:Magnesium / Q000378:metabolism*; D008297:Male; D011188:Potassium / Q000378:metabolism*; D017680:Potassium Compounds; D012964:Sodium / Q000378:metabolism* / Q000494:pharmacology; D017693:Sodium Bicarbonate; D013552:Swine / Q000378:metabolism*
chemical_list: D001639:Bicarbonates; D002712:Chlorides; D017680:Potassium Compounds; D017693:Sodium Bicarbonate; D012964:Sodium; C026329:potassium bicarbonate; D008274:Magnesium; D011188:Potassium; D002118:Calcium