GMP-stimulation of the cyanide-insensitive mitochondrial respiration in heat-shocked conidia of Neurospora crassa.
In mitochondria of heat-shocked conidia of Neurospora exogenous NADH and succinate were oxidized mainly via the alternative, hydroxamate-sensitive pathway (70%) and only 30% via the cytochromic, cyanide-sensitive pathway which was predominant in untreated conidia; the alternative oxidase pathway was markedly stimulated by guanosine 5'-monophosphate (GMP).
D003486:Cyanides / Q000494:pharmacology*; D006150:Guanine Nucleotides / Q000494:pharmacology*; D006157:Guanosine Monophosphate / Q000494:pharmacology*; D006358:Hot Temperature; D008928:Mitochondria / Q000378:metabolism*; D009243:NAD / Q000378:metabolism; D009491:Neurospora / Q000378:metabolism*; D009492:Neurospora crassa / Q000378:metabolism*; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000378:metabolism; D010101:Oxygen Consumption / Q000187:drug effects; D011190:Potassium Cyanide / Q000494:pharmacology*; D013386:Succinates / Q000378:metabolism; D019802:Succinic Acid
D003486:Cyanides; D006150:Guanine Nucleotides; D013386:Succinates; D009243:NAD; D006157:Guanosine Monophosphate; D019802:Succinic Acid; D010088:Oxidoreductases; C022691:succinate oxidase; D011190:Potassium Cyanide