title: [Immunohematologic changes in pituitary adenomas].
abstract: The authors conducted studies of colony-producing capacity of precursor cells of bone marrow granulomonopoiesis and cytogenetic study of blood T lymphocytes in 13 patients with adenoma of the hypophysis. It was established that adenomas of the hypophysis are attended by the development of functional deficiency of T lymphocytes and the resultant disturbance of T cell regulation of granulomonopoiesis. The disorder of granulomonopoiesis occurs at the level of the precursor cells in the bone marrow.
mesh_terms: D000239:Adenoma, Acidophil / Q000378:metabolism*; D000238:Adenoma, Chromophobe / Q000378:metabolism*; D000328:Adult; D001772:Blood Cell Count; D001853:Bone Marrow / Q000473:pathology*; D005260:Female; D013006:Growth Hormone / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000276:immunology / Q000378:metabolism* / Q000473:pathology; D011388:Prolactin / Q000378:metabolism*; D013601:T-Lymphocytes / Q000276:immunology*; D013972:Thyrotropin / Q000378:metabolism*
chemical_list: D011388:Prolactin; D013972:Thyrotropin; D013006:Growth Hormone
vernacular_title: Immunogematologicheskie izmeneniia pri adenomakh gipofiza.