[In vitro activity of various antimalarials (chloroquine, amodiaquine, quinine and mefloquine) against 32 isolates of Plasmodium falciparum in French Guiana].
The in vitro susceptibility of various Plasmodium falciparum isolates obtained from patients infected in French Guiana was tested in a semi-microtest, using four antimalarial drugs. 90.6% of 32 isolates were resistant to chloroquine, 40% to amodiaquine and 17% to quinine. All the 17 isolates were susceptible to mefloquine.
D000655:Amodiaquine / Q000494:pharmacology*; D000818:Animals; D002738:Chloroquine / Q000494:pharmacology*; D004351:Drug Resistance; D005616:French Guiana; D015767:Mefloquine; D010963:Plasmodium falciparum / Q000187:drug effects*; D011803:Quinine / Q000494:pharmacology*; D011804:Quinolines / Q000494:pharmacology*
D011804:Quinolines; D000655:Amodiaquine; D002738:Chloroquine; D011803:Quinine; D015767:Mefloquine
Note sur l'activité in vitro de divers antipaludéens (chloroquine, amodiaquine, quinine et mefloquine) contre 32 isolats de Plasmodium falciparum de Guyane française.