Phosphocholinetransferase activity in plasma membrane: effect of diet.
The presence of phosphocholinetransferase, a component of the CDP-choline pathway for phosphatidylcholine biosynthesis is demonstrated in brain synaptic plasma membrane. Activity of phosphocholinetransferase is higher in weanling versus adult tissues, and responds to alterations in fat intake. The implications of phosphocholinetransferase activity in plasma membrane, and dietary manipulation of phosphatidylcholine biosynthesis via this pathway are discussed.
D000375:Aging; D000818:Animals; D001921:Brain / Q000201:enzymology* / Q000254:growth & development; D002462:Cell Membrane / Q000201:enzymology; D002798:Diacylglycerol Cholinephosphotransferase / Q000378:metabolism*; D004041:Dietary Fats / Q000494:pharmacology*; D007425:Intracellular Membranes / Q000201:enzymology; D007700:Kinetics; D008297:Male; D008861:Microsomes / Q000201:enzymology; D010770:Phosphotransferases / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013570:Synaptic Membranes / Q000201:enzymology*
D004041:Dietary Fats; D010770:Phosphotransferases; D002798:Diacylglycerol Cholinephosphotransferase