[The role of postoperative radiotherapy in the treatment of hypernephroid carcinoma].
The following results can be derived from the clinical and radiobiological literature as well as from the authors's own experiences with 91 patients analyzed retrospectively and evaluated with respect to their risk factors. 1. A postoperative irradiation is very probably sensible in patients with tumor perforation through the renal capsule (T3/T4) and with venous or lymph node manifestations. 2. The operation method is essential, above all the transabdominal technique and the quality of lymph dissection. 3. Prospective studies are necessary in order to clear up the role of radiotherapy in patients with lymph node manifestations and the other two risk factors mentioned in item 1. 4. Further studies on the tumor biology of the hypernephroid carcinoma are necessary in order to gain prognostic criteria allowing a pretherapeutic sensitivity recognition. 5. The effect of a supplementary radiotherapy can be only that of local recurrence prevention in case of a locally advanced tumor and the absence of demonstrable remote metastases. This seems justified, because the local recurrence rate in our own patients was only 3.3%.
D002292:Carcinoma, Renal Cell / Q000532:radiotherapy* / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D008297:Male
Die Rolle der postoperativen Strahlentherapie bei der Behandlung des hypernephroiden Karzinoms.