Congenital Lambert-Eaton myasthenic syndrome.
A 4 year old girl had been hypotonic and areflexic since birth with delayed milestones in motor development. Repetitive stimulation at high rates performed at 3 years elicited an incremental response typical of the Lambert-Eaton Syndrome.
D000200:Action Potentials; D001706:Biopsy; D002675:Child, Preschool; D004576:Electromyography; D005260:Female; D019791:Guanidine; D006146:Guanidines / Q000627:therapeutic use; D006801:Humans; D009132:Muscles / Q000473:pathology / Q000503:physiopathology; D009135:Muscular Diseases / Q000151:congenital* / Q000188:drug therapy / Q000503:physiopathology; D010523:Peripheral Nervous System Diseases / Q000151:congenital* / Q000503:physiopathology; D010543:Peroneal Nerve / Q000503:physiopathology; D013577:Syndrome
D006146:Guanidines; D019791:Guanidine