title: Human alpha-globin maps to pter-p13.3 in chromosome 16 distal to PGP.
abstract: Fibroblasts from a fetus with an unbalanced karyotype 46(XY), -16,+(16qter-16p13.3::4q31.1-4qter) were found to possess only one allele at the 3' hypervariable region (3'HVR) close to the alpha-globin locus and two alleles at the PGP locus. This places the alpha-globin locus at the very tip of 16p, distal to PGP.
mesh_terms: D002871:Chromosome Banding; D002874:Chromosome Mapping; D002885:Chromosomes, Human, Pair 16; D005260:Female; D008040:Genetic Linkage; D005819:Genetic Markers; D005914:Globins / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D008297:Male; D010375:Pedigree; D010744:Phosphoric Monoester Hydrolases / Q000235:genetics*
chemical_list: D005819:Genetic Markers; D005914:Globins; C022408:phosphoglycolate phosphatase; D010744:Phosphoric Monoester Hydrolases