Adrenergic nerves and the delay phenomenon.
The present study indicates that adrenergic nerves can in part explain the delay phenomenon. Data presented suggest that degeneration in release of norepinephrine might be deleterious to critical parts of a skin flap. This could be avoided by performing a delay procedure, as no release of norepinephrine will occur after the second operation.
D000255:Adenosine Triphosphate / Q000032:analysis; D000818:Animals; D000242:Cyclic AMP / Q000032:analysis; D003714:Denervation; D005260:Female; D006085:Graft Survival; D009336:Necrosis / Q000517:prevention & control*; D009638:Norepinephrine / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains; D013518:Surgery, Plastic / Q000379:methods*; D013524:Surgical Flaps; D013564:Sympathetic Nervous System / Q000503:physiopathology*; D013997:Time Factors
D000255:Adenosine Triphosphate; D000242:Cyclic AMP; D009638:Norepinephrine