Intrathecal immunoglobulin production and minor motor seizures.
Five infants with idiopathic infantile minor motor seizures had an elevated immunoglobulin G (IgG) index ((cerebrospinal fluid IgG/serum IgG):(cerebrospinal fluid albumin/serum albumin)). The infants had prolonged prodromal symptoms, and bad prognosis. It is suggested that immunological mechanisms may contribute to the pathophysiology in certain cases of infantile spasms.
D000324:Adrenocorticotropic Hormone / Q000627:therapeutic use; D000367:Age Factors; D000418:Albumins / Q000134:cerebrospinal fluid; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007223:Infant; D012640:Seizures / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology*; D012709:Serum Albumin / Q000032:analysis; D013036:Spasms, Infantile / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology
D000418:Albumins; D007074:Immunoglobulin G; D012709:Serum Albumin; D000324:Adrenocorticotropic Hormone