Persistent bactericidal defect in neutrophils from a young woman who recovered from toxic shock syndrome.
We have previously found transient menstruation-associated abnormalities in the in vitro bactericidal function of neutrophils from females who have recovered from toxic shock syndrome (TSS). We now report the case of a young woman who has also recovered from TSS, but who has a persistent, non-menstruation-associated defect in the ability of her neutrophils to kill Staphylococcus aureus in vitro.
D000293:Adolescent; D000469:Alkaline Phosphatase / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D066298:In Vitro Techniques; D009113:Muramidase / Q000097:blood; D009504:Neutrophils / Q000187:drug effects / Q000502:physiology*; D009195:Peroxidase / Q000097:blood; D010587:Phagocytosis; D012772:Shock, Septic / Q000097:blood*; D013203:Staphylococcal Infections / Q000097:blood*; D013211:Staphylococcus aureus; D013481:Superoxides / Q000097:blood; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology
D013481:Superoxides; D009195:Peroxidase; D000469:Alkaline Phosphatase; D009113:Muramidase; D013755:Tetradecanoylphorbol Acetate