Present knowledge of poliovirus and perspectives for future vaccines.
Will currently used poliovirus vaccines be improved or be replaced with new ones? By analyzing recent data on poliovirus antigenicity and on the molecular basis of its attenuation, we have tried to answer this question.
D000956:Antigens, Viral / Q000276:immunology; D004274:DNA, Recombinant; D009500:Neutralization Tests; D011051:Poliomyelitis / Q000517:prevention & control*; D017955:Poliovirus / Q000502:physiology*; D014613:Vaccines, Attenuated / Q000276:immunology; D014765:Viral Vaccines / Q000592:standards*
D000956:Antigens, Viral; D004274:DNA, Recombinant; D014613:Vaccines, Attenuated; D014765:Viral Vaccines