title: Rapid diagnosis of herpes simplex virus infections in conventional and shell vial cell cultures using monoclonal antibodies.
abstract: One hundred specimens for herpes simplex virus (HSV) isolation were tested in parallel by conventional and by centrifugation-enhanced cell culture, followed by identification using monoclonal antibodies to HSV-1 and HSV-2. Sensitivity was comparable by the two methods; conventional culture was only marginally slower and was easier to fit into the routine of a busy laboratory. It is, therefore, advocated for HSV detection in clinical specimens.
mesh_terms: D000911:Antibodies, Monoclonal / Q000276:immunology*; D000914:Antibodies, Viral / Q000276:immunology*; D002478:Cells, Cultured; D002498:Centrifugation; D046508:Culture Techniques / Q000295:instrumentation; D006561:Herpes Simplex / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D018139:Simplexvirus / Q000276:immunology*; D013997:Time Factors
chemical_list: D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral