Biofiltration with bicarbonate as dialysate buffer.
The biofiltration with bicarbonate as dialysate buffer (BiBF) was used in 10 patients on RDT: the patients were treated for 10 months on standard BF and for 10 months on BiBF. The amount of fluid infused varied between 3 and 5 liters and Na-bicarbonate (100 mEq/h) was infused during BF. The dialytic protocol was 3 hours every other day. Cardiovascular stability, waste molecules and acid-base balance were investigated. No differences in vascular stability and no significant changes in the waste-molecules concentrations were found. Both protocols correct the metabolic acidosis; however, in standard BF 50% of patients showed acute hypocapnia at the end of dialysis.
D000136:Acid-Base Equilibrium; D000138:Acidosis / Q000097:blood; D001639:Bicarbonates / Q000008:administration & dosage*; D001769:Blood; D002021:Buffers; D002245:Carbon Dioxide / Q000097:blood; D006801:Humans; D007022:Hypotension / Q000097:blood; D006435:Renal Dialysis; D012964:Sodium / Q000008:administration & dosage*; D017693:Sodium Bicarbonate; D012965:Sodium Chloride / Q000008:administration & dosage; D014462:Ultrafiltration / Q000379:methods*
D001639:Bicarbonates; D002021:Buffers; D002245:Carbon Dioxide; D012965:Sodium Chloride; D017693:Sodium Bicarbonate; D012964:Sodium