title: Oxytocin release during coitus in male and female rabbits: effect of opiate receptor blockade with naloxone.
abstract: Blood was collected from freely moving rabbits pretreated with saline or naloxone both before and after coitus. In the males, ejaculation was associated with a marked increase in plasma oxytocin concentrations. In the females, oxytocin release was an all-or-nothing phenomenon-either there was no change in oxytocin or it rose to levels very similar to that found post-ejaculation in the males. Naloxone did not alter the proportion of occasions in which females showed an oxytocin response, nor did it have a significant effect on the levels of oxytocin achieved during coitus in either the male or the female rabbits.
mesh_terms: D000818:Animals; D003307:Copulation / Q000502:physiology*; D005260:Female; D008297:Male; D009270:Naloxone / Q000494:pharmacology*; D010121:Oxytocin / Q000378:metabolism*; D011817:Rabbits; D011957:Receptors, Opioid / Q000502:physiology*; D012149:Restraint, Physical; D012727:Sex Characteristics; D013312:Stress, Physiological / Q000503:physiopathology
chemical_list: D011957:Receptors, Opioid; D009270:Naloxone; D010121:Oxytocin