title: [Cholinergic regulation of the activity of somatosensory cortex neurons during early postnatal ontogeny of the cat].
abstract: In 11-14 days kittens, about 20% of neurones in the somatosensory cortical zone react to stimulation of subpallidal region which is a source of cholinergic projections to the cerebral cortex. The effect of subpallidal region stimulation is reproduced in case of microiontophoretic acetylcholine application and blocked by atropine what points to its cholinergic nature. Cholinergic stimulation causes inhibition of the background and evoked activities of the cortical neurones while, as it is known, in adult cats, acetylcholine mainly stimulates a reaction of activation. It is postulated that in kittens at the end of the second week of postnatal development, cholinergic innervation of the cortex significantly differs from the definitive one by its quantitative and functional parameters.
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology; D000344:Afferent Pathways / Q000502:physiology; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D002415:Cats; D002799:Cholinergic Fibers / Q000502:physiology; D005071:Evoked Potentials; D008297:Male; D009044:Motor Cortex / Q000254:growth & development*; D009433:Neural Inhibition; D013003:Somatosensory Cortex / Q000254:growth & development*; D013127:Spinal Nerves / Q000502:physiology; D009435:Synaptic Transmission / Q000187:drug effects
chemical_list: D001285:Atropine; D000109:Acetylcholine
vernacular_title: Kholinergicheskaia reguliatsiia aktivnosti neĭronov somatosensornoĭ kory v rannem postnatal'nom ontogeneze koshki.