Effect of enteral feeding bag composition and freezing and thawing upon vitamin stability in an enteral feeding solution.
The effect of enteral feeding bag composition and freezing and thawing upon the stability of riboflavin and vitamins A and E in an enteral feeding solution was tested. Feeding bags composed of either polyvinyl chloride or polyethylene were filled with an enteral feeding solution. The samples were frozen for 3 months, thawed in warm water, and allowed to stand in room temperature for 12 hr. Samples for vitamin analysis were obtained prior to freezing, upon thawing, and at 12 hr after thawing. No significant differences in vitamin stability due to bag composition or time were seen. These results support the viability of the concept of mixing large batches of enteral feeding solution, and freezing aliquots in individual feeding bags for later use.
Davis
A T
AT
Fagerman
K E
KE
Downer
F D
FD
Dean
R E
RE
D004355:Drug Stability; D004750:Enteral Nutrition / Q000295:instrumentation* / Q000379:methods; D005615:Freezing; D006801:Humans; D011095:Polyethylenes; D011143:Polyvinyl Chloride; D012256:Riboflavin / Q000008:administration & dosage; D012996:Solutions; D014801:Vitamin A / Q000008:administration & dosage; D014810:Vitamin E / Q000008:administration & dosage; D014815:Vitamins / Q000008:administration & dosage*
D011095:Polyethylenes; D012996:Solutions; D014815:Vitamins; D014801:Vitamin A; D014810:Vitamin E; D011143:Polyvinyl Chloride; D012256:Riboflavin