title: [Acyclovir in herpes neonatorum].
abstract: In case of vaginal delivery herpes genitalis of pregnant women is the main reason for infection of the new-born. According to Anne Yeager, 2.4% of pregnant women with a past history if HSV infections are asymptomatically shedding herpes viruses at term without manifestation of a herpes infection of the new-born in most cases. The reasons for this could be: a sufficient antibody titre of the new-born (diaplacental transmission of maternal antibodies; term infant. According to Whitley the morbidity is about 1 to 5 infections per 10,000 deliveries; 50% of the infected infants do not show any cutaneous efflorescences and could therefore be wrong diagnosed.
authors.affiliation: Deutsche Wellcome GmbH, Med. Wissenschaftliche Abt., Burgwedel 1.
authors.forename: J
authors.initials: J
authors.lastname: Schumann
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use*; D005260:Female; D006558:Herpes Genitalis / Q000188:drug therapy; D006561:Herpes Simplex / Q000188:drug therapy*; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy
chemical_list: D000212:Acyclovir
vernacular_title: Aciclovir beim Herpes neonatorum.