title: New application of the autotrans: autologous support of the organ donor and salvage of the donor's red blood cells for the transfusion support of organ recipients.
abstract: Organ donation is usually limited to solid tissues; paradoxically, organ donors undergoing explant are often transfused in preparation for or during surgery. This practice increases the requirement for blood and adds immunological and infectious risks for both recipients and donors of grafts. We have investigated the possibility of supporting an explant with intraoperative blood salvage and, in the case of a cadaver donor, at the end of the operation, salvaging blood for potential use in the graft recipient. This preliminary report describes the technique and the results obtained in two procedures. The volume of red cells with a hematocrit of 55% obtained from the two donors was 2,090 and 1,180 ml, respectively. These components were employed for the transfusion support of the organ recipients.
authors.affiliation: Department of Transplantation Medicine, San Martino Regional University Hospital, Genova, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Valbonesi
authors.forename: M
authors.initials: M
authors.lastname: Ferrari
authors.forename: S
authors.initials: S
authors.lastname: Zia
authors.forename: C
authors.initials: C
authors.lastname: Piri
authors.forename: M
authors.initials: M
authors.lastname: Fella
authors.forename: P
authors.initials: P
authors.lastname: Pittaluga
authors.forename: C
authors.initials: C
authors.lastname: Zat
authors.forename: A
authors.initials: A
authors.lastname: Concaro
authors.forename: I
authors.initials: I
authors.lastname: Fontana
authors.forename: F
authors.initials: F
authors.lastname: DeStefano
mesh_terms: D001781:Blood Component Removal / Q000295:instrumentation / Q000379:methods; D001804:Blood Transfusion, Autologous / Q000295:instrumentation / Q000379:methods; D002102:Cadaver; D017707:Erythrocyte Transfusion; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D014019:Tissue Donors; D009927:Tissue and Organ Procurement / Q000379:methods