[Changes in the indicators of the renin-angiotensin-aldosterone system, kallikrein-kinin system and arterial blood pressure in elderly patients with essential hypertension treated with captopril].
The magnitude of captopril hypotensive effect, and variation in renin-angiotensin-aldosterone and kallikrein-kinin parameters were examined in patients with advanced essential hypertension in the presence of normal and low plasma renin activity. The demonstrated differences in the patterns of arterial BP, renin-angiotensin and kallikrein-kinin change have suggested that low-renin essential hypertension is resistant to captopril in most cases.
Khartrodt
V
V
Brozovskiĭ
K Kh
KKh
Beuer
E
E
Gurke
R
R
Faulhaber
H
H
D000328:Adult; D000367:Age Factors; D000368:Aged; D000450:Aldosterone / Q000378:metabolism*; D001794:Blood Pressure; D002216:Captopril / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology*; D007610:Kallikreins / Q000097:blood*; D007704:Kininogens / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012084:Renin-Angiotensin System
D007704:Kininogens; D000450:Aldosterone; D002216:Captopril; D007610:Kallikreins
Izmenenie pokazateleĭ renin-angiotenzin-al'dosteronovoĭ, kallikrein-kininovoĭ sistem i AD u bol'nykh éssentsial'noĭ gipertonieĭ pozhilogo vozrasta pri lechenii kaptoprilom.