title: [Bacteremias after bone marrow grafts in a protected environment: effects, various aspects and prognosis].
abstract: We evaluated retrospectively the incidence and prognosis of bacteremias after bone marrow transplantation treated in protected environment with intestinal decontamination. Bacteremias are more frequent during the extreme granulopenia (55% of the patients) than during recovery of granulocyte counts greater than 500/mm3 (35% of the patients). Gram + organisms are more frequently responsible of bacteremias (80%), mainly Staphylococcus epidermidis and Streptococci. Mortality is low (7%) and related to additional factors like GVH, resistant leukemia. These data invite to develop new approaches of prevention of bacterial infection, with measures possibly efficient on Gram + organisms.
authors.affiliation: Unité de Transplantation Médullaire, INSERM U 119, Marseille, France.
authors.forename: G
authors.initials: G
authors.lastname: Michel
authors.forename: D
authors.initials: D
authors.lastname: Maraninchi
authors.forename: D
authors.initials: D
authors.lastname: Blaise
authors.forename: A M
authors.initials: AM
authors.lastname: Stoppa
authors.forename: J A
authors.initials: JA
authors.lastname: Gastaut
authors.forename: J
authors.initials: J
authors.lastname: Camerlo
authors.forename: M H
authors.initials: MH
authors.lastname: Gaspard
authors.forename: G
authors.initials: G
authors.lastname: Novakovitch
authors.forename: Y
authors.initials: Y
authors.lastname: Carcassonne
mesh_terms: D000293:Adolescent; D000328:Adult; D016026:Bone Marrow Transplantation; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D010356:Patient Isolation; D011183:Postoperative Complications; D011379:Prognosis; D018805:Sepsis / Q000453:epidemiology / Q000209:etiology*; D013203:Staphylococcal Infections / Q000209:etiology; D013212:Staphylococcus epidermidis; D013290:Streptococcal Infections / Q000209:etiology
vernacular_title: Bactériémies après greffe de moelle en environnement protégé: incidence, aspects et pronostic.