title: Semiautomated renal region-of-interest selection method: validation in a dog model.
abstract: A successful method of automated region-of-interest (ROI) selection by polar edge search for use in technetium-99m-diethylenetriaminepentacetate (99mTc-DTPA) renography is presented in a dog model. The accuracy of the resultant ROI was tested by comparing renal uptake within the ROI to simultaneously monitored arterial 99mTc-DTPA concentration. The automatically selected ROI resulted in renal uptake curves that better matched arterial clearance than either systematically larger and smaller ROIs or a manually chosen ROI.
authors.affiliation: Department of Radiological Sciences, School of Veterinary Medicine, University of California, Davis 95616.
authors.forename: W J
authors.initials: WJ
authors.lastname: Hornof
authors.forename: L D
authors.initials: LD
authors.lastname: Cowgill
authors.forename: G R
authors.initials: GR
authors.lastname: Conrad
authors.forename: P
authors.initials: P
authors.lastname: Fisher
mesh_terms: D000465:Algorithms; D000818:Animals; D004285:Dogs; D005919:Glomerular Filtration Rate; D009942:Organometallic Compounds; D004369:Pentetic Acid; D011866:Radioisotope Renography / Q000379:methods*; D016284:Technetium Tc 99m Pentetate
chemical_list: D009942:Organometallic Compounds; D004369:Pentetic Acid; D016284:Technetium Tc 99m Pentetate