title: [Methodological approaches to the evaluation of the effectiveness of anti-anginal preparations in patients with stenocardia by 24-hour ECG monitoring].
abstract: Scientific rationale are given for methodological approaches promoting improved reproducibility of 24-hour ECG monitoring data, for the method to be used repeatedly in assessing patient's condition. Repeated 24-hour-ECG monitoring in identical motor conditions (a standard mobility regimen) has been shown to improve considerably the reproducibility of its results. Criteria for the efficiency of antianginal therapy in patients with angina of the 2nd and 3d functional classes, as evidenced by 24-hour ECG monitoring, have been developed and substantiated. They are a drop in the number of ST depression episodes (by 3 and more) and in the total depth of depression (by 50% and more). The sensitivity of the assessment of each of the two indicators of myocardial ischemia or their combination was 70%, and the specificity was 77.8% and 88.9%, respectively.
authors.forename: V I
authors.initials: VI
authors.lastname: Metelítsa
authors.forename: R S
authors.initials: RS
authors.lastname: Vodop'ianova
authors.forename: E V
authors.initials: EV
authors.lastname: Kokurina
authors.forename: O S
authors.initials: OS
authors.lastname: Riabokon'
authors.forename: E V
authors.initials: EV
authors.lastname: Bochkareva
mesh_terms: D000328:Adult; D000787:Angina Pectoris / Q000188:drug therapy* / Q000503:physiopathology; D002940:Circadian Rhythm; D002986:Clinical Trials as Topic; D004562:Electrocardiography; D005080:Exercise Test; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods; D009200:Myocardial Contraction / Q000187:drug effects*; D009543:Nifedipine / Q000627:therapeutic use*; D010919:Placebos; D014700:Verapamil / Q000627:therapeutic use*
chemical_list: D010919:Placebos; D014700:Verapamil; D009543:Nifedipine
vernacular_title: Metodicheskie podkhody k otsenke éffektivnosti antianginal'nykh preparatov u bol'nykh so stenokardieĭ s pomoshch'iu sutochnogo monitorirovaniia EKG.