Localisation of several chromosome I genes of Aspergillus nidulans: implications for mitotic recombination.
Another laboratory previously reported that the vast majority of mitotic recombinants in chromosome I disomics of Aspergillus nidulans arise from double exchange events involving the centromeric region and a far distal, possibly telomeric, region. This conclusion was based on the assumption that the camC gene is located in a position far distal to the centromere on the left arm of chromosome I. As a left arm location for camC distal to the centromere was possibly in conflict with mapping data obtained in the context of an unrelated project, camC was partially mapped along with three other previously unlocated chromosome I genes, davA, ornD and uapA. The data presented here indicate that camC is located in a position far distal to the centromere but on the right arm of chromosome I, a conclusion also supported by the previous data. The positioning of uapA and camC in far distal locations on the right arm of chromosome I indicates the existence of a vast, otherwise nearly unmapped region on this chromosome arm.
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Department of Bacteriology, Royal Postgraduate Medical School, London, UK.
D001233:Aspergillus nidulans / Q000235:genetics*; D002874:Chromosome Mapping; D004171:Diploidy; D005800:Genes, Fungal; D008040:Genetic Linkage; D008540:Meiosis; D008938:Mitosis; D009154:Mutation; D011995:Recombination, Genetic; D014178:Translocation, Genetic