title: The presence of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in smoked dry bonito (katsuobushi).
abstract: Smoked dry bonito (katsuobushi), an everyday food item for most Japanese people, was found to contain 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), the content of which was estimated at about 2 ng/g. This content is similar to the known MeIQx content of cooked beef. The katsuobushi also contained another mutagenic component, the total activity of which was 1/6-1/3 that of the MeIQx. This component was similar to 2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline (4,8-DiMeIQx) with respect to its behavior in high-pressure liquid chromatography and its ultraviolet absorption spectrum.
authors.forename: K
authors.initials: K
authors.lastname: Kikugawa
authors.forename: T
authors.initials: T
authors.lastname: Kato
authors.forename: H
authors.initials: H
authors.lastname: Hayatsu
mesh_terms: D002851:Chromatography, High Pressure Liquid; D005396:Fish Products / Q000032:analysis*; D005511:Food Handling; D009153:Mutagens / Q000032:analysis*; D011810:Quinoxalines / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D009153:Mutagens; D011810:Quinoxalines; C036990:2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline