title: [Protein restriction and metabolism of xenobiotics].
abstract: Young male rats were fed a balanced diet or a low-protein diet (casein 6%; w/w) for 6 weeks. After 2 weeks, each group was divided, one half being maintained as the control and the other half being fed diet-containing (Phenoclor DP6) at a level of 50 mg/kg for 4 weeks. A low-protein diet lowered the liver glutathione content and the activity of the mono-oxygenases. It lowered the inductive effect of PCB towards P450, NADPH-cytochrome c reductase, aminopyrine demethylase and aniline hydroxylase, but it raised the benzo(a) pyrene hydroxylase induction.
authors.forename: R
authors.initials: R
authors.lastname: Albrecht
authors.forename: M A
authors.initials: MA
authors.lastname: Pelissier
authors.forename: N
authors.initials: N
authors.lastname: Miladi
authors.forename: S
authors.initials: S
authors.lastname: Atteba
authors.forename: C
authors.initials: C
authors.lastname: Desfontaines
authors.forename: J F
authors.initials: JF
authors.lastname: Narbonne
mesh_terms: D000633:Aminopyrine N-Demethylase / Q000378:metabolism; D000815:Aniline Hydroxylase / Q000378:metabolism; D000818:Animals; D001579:Benzopyrene Hydroxylase / Q000378:metabolism; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004044:Dietary Proteins / Q000378:metabolism*; D002149:Energy Intake; D005978:Glutathione / Q000378:metabolism; D008099:Liver / Q000033:anatomy & histology; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D009251:NADPH-Ferrihemoprotein Reductase / Q000378:metabolism; D009929:Organ Size; D011078:Polychlorinated Biphenyls / Q000378:metabolism; D051381:Rats
chemical_list: D004044:Dietary Proteins; D003577:Cytochrome P-450 Enzyme System; D011078:Polychlorinated Biphenyls; D006899:Mixed Function Oxygenases; D000815:Aniline Hydroxylase; D001579:Benzopyrene Hydroxylase; D000633:Aminopyrine N-Demethylase; D009251:NADPH-Ferrihemoprotein Reductase; D005978:Glutathione
vernacular_title: Restriction protéique et métabolisme des xénobiotiques.