title: [Tubulointerstitial nephritis in Conn's syndrome].
abstract: The evaluation of 79 renal biopsies from patients with primary aldosteronism established pathology in one-fourth of the examinees. There were specific dystrophic and atrophic lesions of the tubular apparatus, focal interstitial sclerosis and disseminated round-cell infiltrates. Immunomorphological evaluation showed these to have macrophages and T lymphocytes as cellular components. The process manifested clinically by steady hypofunction of osmotic diuresis in the absence of bacterial inflammation and calycine-pelvic destruction. No relation of this condition with inflammation in onset and signs of immune origin of such give good grounds to refer the pathology to tubulointerstitial nephritides of immune genesis.
authors.forename: R I
authors.initials: RI
authors.lastname: Sokolova
authors.forename: V S
authors.initials: VS
authors.lastname: Zhdanov
authors.forename: S E
authors.initials: SE
authors.lastname: Ustinova
mesh_terms: D000911:Antibodies, Monoclonal; D006801:Humans; D006929:Hyperaldosteronism / Q000473:pathology*; D007124:Immunoenzyme Techniques; D007668:Kidney / Q000473:pathology / Q000648:ultrastructure; D009395:Nephritis, Interstitial / Q000473:pathology*
chemical_list: D000911:Antibodies, Monoclonal
vernacular_title: K voprosu o tubulointerstitsial'nom nefrite pri sindrome Konna.