title: Wound healing as a barrier to successful filtration surgery.
abstract: Trabeculectomy fails to control the intra-ocular pressure adequately in a proportion of patients. Approaches to solving this problem have involved modifications of surgery, histological studies of tissue from failed and functioning blebs, animal studies, and in vitro investigations of some of the basic processes of wound healing. This paper reviews the current state of investigations in these disciplines with particular reference to wound healing in this specialised site.
authors.affiliation: Institute of Ophthalmology, London.
authors.forename: J P
authors.initials: JP
authors.lastname: Joseph
authors.forename: M H
authors.initials: MH
authors.lastname: Miller
authors.forename: R A
authors.initials: RA
authors.lastname: Hitchings
mesh_terms: D000818:Animals; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D014130:Trabeculectomy; D014945:Wound Healing