Pregnancies after premature ovarian failure.
Six women who conceived after a diagnosis of premature ovarian failure are discussed. Two pregnancies occurred while the women were receiving conjugated estrogen therapy, two while taking oral contraceptives, and two women conceived spontaneously. The possible role of exogenous estrogens in sensitizing the granulosa cells to the effect of follicle-stimulating hormone and thereby inducing ovulation and conception in some women with premature ovarian failure is examined.
Alper
M M
MM
Jolly
E E
EE
Garner
P R
PR
D000293:Adolescent; D000328:Adult; D000568:Amenorrhea / Q000188:drug therapy / Q000209:etiology; D000818:Animals; D001943:Breast Neoplasms / Q000150:complications; D004967:Estrogens / Q000627:therapeutic use; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism; D006107:Granulosa Cells / Q000378:metabolism; D006689:Hodgkin Disease / Q000150:complications; D006801:Humans; D007231:Infant, Newborn; D015470:Leukemia, Myeloid, Acute / Q000150:complications; D008297:Male; D008593:Menopause; D008594:Menopause, Premature; D010053:Ovary / Q000503:physiopathology; D011247:Pregnancy; D051381:Rats; D014424:Turner Syndrome / Q000150:complications
D004967:Estrogens; D005640:Follicle Stimulating Hormone