Lymphogranuloma venereum conjunctivitis with a marginal corneal perforation.
The authors have recently treated a case of Parinaud's oculoglandular syndrome due to Chlamydia trachomatis serotype L2, a causative agent of lymphogranuloma venereum (LGV). The ocular manifestations included a mixed papillary-follicular conjunctivitis with fleshy superior limbal lesions in both eyes. A superior marginal corneal perforation requiring a therapeutic corneal graft was present in the right eye. The patient had vaginitis, inguinal lymphadenopathy, a history of Sjögren's syndrome, and seropositivity to human immunodeficiency virus (HIV). The ocular disease resolved completely after 6 weeks of oral tetracycline therapy.
Buus
D R
DR
Department of Ophthalmology, University of Miami School of Medicine, Bascom Palmer Eye Institute, FL 33101.
Pflugfelder
S C
SC
Schachter
J
J
Miller
D
D
Forster
R K
RK
D000293:Adolescent; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D003228:Conjunctiva / Q000382:microbiology / Q000473:pathology; D003231:Conjunctivitis / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D003316:Corneal Diseases / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D016039:Corneal Transplantation; D005260:Female; D006801:Humans; D008219:Lymphogranuloma Venereum / Q000150:complications*