title: Evaluation of the effects of elastic compression in patients with postphlebitic limbs by laser-Doppler flowmetry.
abstract: Laser-Doppler flowmetry has been used to study the skin microcirculation in 20 normal limbs and 80 limbs of patients with venous hypertension and leg ulceration due to deep venous reflux. It was found that limbs with venous hypertension had a high skin resting blood flow (BRF) and an impaired veno-arteriolar reflex (VR). There was a marked improvement in both BRF and VR after elastic compression for three weeks and an association between this improvement and the rate of healing of the leg ulcers. The results indicate that elastic compression may affect the microcirculation even though it does not alter the venous pressure measurements when the elastic stockings are removed.
authors.affiliation: Irvine Laboratory for Cardiovascular Investigation and Research, St Mary's Hospital Medical School, London, UK.
authors.forename: G
authors.initials: G
authors.lastname: Belcaro
authors.forename: M
authors.initials: M
authors.lastname: Grigg
authors.forename: S
authors.initials: S
authors.lastname: Vasdekis
authors.forename: A
authors.initials: A
authors.lastname: Rulo
authors.forename: D
authors.initials: D
authors.lastname: Christopoulos
authors.forename: A
authors.initials: A
authors.lastname: Nicolaides
mesh_terms: D000328:Adult; D000368:Aged; D003020:Clothing; D005069:Evaluation Studies as Topic; D006801:Humans; D007834:Lasers; D008833:Microcirculation; D008875:Middle Aged; D011186:Postphlebitic Syndrome / Q000503:physiopathology / Q000628:therapy*; D014463:Ultrasonography; D014690:Venous Pressure