title: A comparison of gemeprost (Cervagem) pessaries and Lamicel tents for cervical preparation for abortion by dilatation and suction.
abstract: In a randomized, single-blind trial, 78 women having vaginal termination of pregnancy were treated with either a 1-mg gemeprost (Cervagem) pessary or a Lamicel tent inserted 3-4 h before operation. Both agents produced satisfactory cervical softening but dilatation was significantly easier after gemeprost. Pre-operative side-effects were more frequent after gemeprost but did not increase the need for analgesia. There were no differences between the two groups with regard to either postoperative symptoms and analgesic requirements or pre-operative and postoperative temperature, pulse rate and blood pressure. Gemeprost pessaries are easier, faster and less uncomfortable to administer.
authors.affiliation: Department of Obstetrics and Gynaecology, Brighton General Hospital, Elm Grove.
authors.forename: C W
authors.initials: CW
authors.lastname: Helm
authors.forename: N
authors.initials: N
authors.lastname: Davies
authors.forename: R J
authors.initials: RJ
authors.lastname: Beard
mesh_terms: D000019:Abortifacient Agents; D000020:Abortifacient Agents, Nonsteroidal; D000032:Abortion, Therapeutic; D000328:Adult; D000527:Alprostadil / Q000008:administration & dosage / Q000031:analogs & derivatives*; D002584:Cervix Uteri / Q000187:drug effects*; D002986:Clinical Trials as Topic; D004107:Dilatation and Curettage; D005260:Female; D006801:Humans; D008278:Magnesium Sulfate / Q000008:administration & dosage*; D010570:Pessaries; D011142:Polyvinyl Alcohol / Q000008:administration & dosage*; D011247:Pregnancy
chemical_list: D000019:Abortifacient Agents; D000020:Abortifacient Agents, Nonsteroidal; C034860:Lamicel; C021182:gemeprost; D008278:Magnesium Sulfate; D011142:Polyvinyl Alcohol; D000527:Alprostadil