title: Splanchnic glucose balance and insulin resistance in the early postoperative phase of cardiac surgery.
abstract: The splanchnic balance of glucose was studied in the basal state and at three levels of "clamped" hyperinsulinemia (260 +/- 23, 510 +/- 59, 3875 +/- 367 mU/liter) in 24 patients (43-70 years of age), who had undergone coronary surgery about 1 hr previously. The splanchnic balance of glucose in the basal state was negative in all patients (-1.6 +/- 0.3 mg/kg/min) and was changed into a zero-balance within 30 min when 0.15 or 0.3 U/kg/hr of insulin was infused. At an insulin infusion rate of 1.0 U/kg/hr the net splanchnic glucose balance was turned into a significant positive balance of an average 0.9 +/- 0.3 mg/kg/min.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Sahlgrenska Hospital, Göteborg, Sweden.
authors.forename: F
authors.initials: F
authors.lastname: Nilsson
authors.forename: R
authors.initials: R
authors.lastname: Ekroth
authors.forename: I
authors.initials: I
authors.lastname: Milocco
authors.forename: N J
authors.initials: NJ
authors.lastname: Nilsson
authors.forename: S
authors.initials: S
authors.lastname: Svensson
authors.forename: E
authors.initials: E
authors.lastname: Berglin
authors.forename: G
authors.initials: G
authors.lastname: William-Olsson
mesh_terms: D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism*; D001026:Coronary Artery Bypass; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood / Q000378:metabolism; D007333:Insulin Resistance; D008297:Male; D008643:Mesentery / Q000378:metabolism*; D008875:Middle Aged; D011184:Postoperative Period
chemical_list: D001786:Blood Glucose; D007328:Insulin