title: Verapamil SR and propranolol LA: a comparison of efficacy and side effects in the treatment of mild to moderate hypertension.
abstract: The efficacy, safety and toleration of sustained release verapamil (Securon SR, Knoll) and long acting propranolol (Inderal LA, ICI) in the treatment of mild to moderate hypertension were compared in a randomized, double-blind, parallel group study. Both drugs were of similar efficacy and were well tolerated in the majority of patients. However, in the verapamil SR treated group side-effects resulted in significantly fewer drug-related withdrawals.
authors.affiliation: The Surgery, Bexley, Kent, UK.
authors.forename: J A
authors.initials: JA
authors.lastname: Bochsler
authors.forename: R L
authors.initials: RL
authors.lastname: Simmons
authors.forename: P J
authors.initials: PJ
authors.lastname: Ward
authors.forename: P C
authors.initials: PC
authors.lastname: Chester
authors.forename: A N
authors.initials: AN
authors.lastname: Latham
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D003692:Delayed-Action Preparations; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011433:Propranolol / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D011897:Random Allocation; D014700:Verapamil / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D003692:Delayed-Action Preparations; D011433:Propranolol; D014700:Verapamil