title: [Crystallins in the differentiation and regeneration processes of the crystalline lens in amphibia].
abstract: The published and authors' data have been summarized on (1) the spectrum and properties of crystallins in different amphibian species, (2) localization and synthesis of crystallins in different cellular compartments of the adult amphibian lens, (3) dynamics of crystallin formation during embryogenesis and (4) lens regeneration from tissues of the larval and adult amphibian eyes. The necessity of more detailed studies of crystallin synthesis during embryogenesis and lens regeneration using molecular biological and biochemical methods is stressed. The significance of this approach is illustrated by the pioneering data of Soviet scientists on crystallin polypeptides and corresponding mRNAs in development of Rana temporaria obtained with the use of DNA-RNA hybridization and immunoelectroblotting.
authors.forename: A T
authors.initials: AT
authors.lastname: Mikhaĭlov
authors.forename: V N
authors.initials: VN
authors.lastname: Simirskiĭ
authors.forename: Zh A
authors.initials: ZhA
authors.lastname: Takenov
mesh_terms: D000663:Amphibians / Q000502:physiology*; D000818:Animals; D002454:Cell Differentiation; D003315:Cornea / Q000502:physiology; D003459:Crystallins / Q000502:physiology*; D004848:Epithelium / Q000502:physiology; D007908:Lens, Crystalline / Q000196:embryology / Q000502:physiology*; D010857:Pigment Epithelium of Eye / Q000502:physiology; D012038:Regeneration
chemical_list: D003459:Crystallins
vernacular_title: Kristalliny v protsessakh differentsirovki i regeneratsii khrustalika glaza amfibiĭ.