title: Histopathological classification of nonantral gastric endocrine growths in man.
abstract: Recently, the gastric endocrine system has been recognized as the origin of benign and malignant tumors in pernicious anemia. It has also been found that the gastric endocrine cells respond to permanent elevation of serum gastrin levels induced by changes in acid secretion in response to surgical procedures, drug therapy and age. Therefore, a definition of nonantral gastric endocrine hyperplasia (simple or diffuse, linear or chain-forming, micronodular, adenomatoid), dysplasia (enlarging or fusing micronodules, microinvasion, nodular growth) and neoplasia (intramucosal carcinoid, invasive carcinoid) is presented. The individual entities are illustrated, together with the literature discussed and the techniques for their identification presented.
authors.affiliation: Department of Human Pathology, University of Pavia, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Solcia
authors.forename: C
authors.initials: C
authors.lastname: Bordi
authors.forename: W
authors.initials: W
authors.lastname: Creutzfeldt
authors.forename: Y
authors.initials: Y
authors.lastname: Dayal
authors.forename: A D
authors.initials: AD
authors.lastname: Dayan
authors.forename: S
authors.initials: S
authors.lastname: Falkmer
authors.forename: L
authors.initials: L
authors.lastname: Grimelius
authors.forename: N
authors.initials: N
authors.lastname: Havu
mesh_terms: D004700:Endocrine System Diseases / Q000145:classification / Q000473:pathology*; D006801:Humans; D013274:Stomach Neoplasms / Q000145:classification / Q000473:pathology* / Q000648:ultrastructure