[Antimicrobial activity of polyhydroxynaphthoquinones from sea urchins].
Antimicrobial activity of polyhydroxynaphthoquinones from sea urchins was studied. 6-Ethyl-2,3,5,7,8-pentahydroxy-1,4-naphthoquinone (equinochrome A) containing the beta-ethyl functional group was found to be the most active substance. Methylation of beta-hydroxyls markedly increased the inhibitory effect of the derivatives as compared to that of the initial quinones.
Stekhova
S I
SI
Shentsova
E B
EB
Kol'tsova
E B
EB
Kulesh
N I
NI
D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D009285:Naphthoquinones / Q000494:pharmacology*; D012617:Sea Urchins; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D009285:Naphthoquinones
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