A small nonconjugative plasmid encoded for streptomycin-resistant character in Shigella dysenteriae.
Conjugative transfers of drug-resistant plasmids in Shigella dysenteriae type 1 isolated from the epidemic in West Bengal were unsuccessful. The plasmids were non-transmissible in spite of having the fertility factor F, genetically labelled with kanamycin-resistant transposon Tn903 (pWS 7). A small 2.5 kb nonconjugative plasmid encoded for the streptomycin-resistant character. Cured plasmid-less strains of S. dysenteriae 1 showed resistance to sulfonamides.
Datta
S
S
National Institute of Cholera and Enteric Diseases, Calcutta, India.
Pal
S C
SC
Chaudhuri
D K
DK
Kumar
R
R
D004352:Drug Resistance, Microbial; D010957:Plasmids; D012762:Shigella dysenteriae / Q000187:drug effects / Q000235:genetics*; D013307:Streptomycin / Q000494:pharmacology*
D013307:Streptomycin