[Can the risk of melanoma be calculated?].
The risk of melanoma of the skin may be calculated in two ways: (1) The cumulative total lifetime exposure to sunlight is responsible for LMM in combination with other light-induced skin damages. Xeroderma pigmentosum is the genetic model for this concept. (2) Particularly intense exposure to the sun in early life seems to be a major provocative factor for NM and SSM as well as for the development of melanoma in dysplastic nevus syndrome.
Jung
E G
EG
Hautklinik, Fakultät für Klinische Medizin Mannheim, Universität Heidelberg.
D004249:DNA Damage; D006801:Humans; D008545:Melanoma / Q000209:etiology* / Q000235:genetics; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D012307:Risk Factors; D012878:Skin Neoplasms / Q000209:etiology* / Q000235:genetics; D014466:Ultraviolet Rays / Q000009:adverse effects
Ist das Melanom-Risiko kalkulierbar?