title: Role of prenatal detection of cardiac tumours in the diagnosis of tuberous sclerosis--report of two cases.
abstract: Tuberous sclerosis is an autosomal dominant disease with variable expression. Little is known about the intrauterine course of the disease and the fetal age at which specific abnormalities may be detected. The role of prenatal detection of cardiac tumours in the diagnosis of two fetuses at 28 and 32 weeks' gestation based on fetal echocardiography is discussed. The prenatal and postnatal course of the disease is described.
authors.affiliation: University of British Columbia, Clinical Genetics Unit, Grace Hospital, Vancouver, Canada.
authors.forename: D
authors.initials: D
authors.lastname: Chitayat
authors.forename: B C
authors.initials: BC
authors.lastname: McGillivray
authors.forename: S
authors.initials: S
authors.lastname: Diamant
authors.forename: B K
authors.initials: BK
authors.lastname: Wittmann
authors.forename: G G
authors.initials: GG
authors.lastname: Sandor
mesh_terms: D000328:Adult; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D006338:Heart Neoplasms / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012207:Rhabdomyoma / Q000150:complications / Q000175:diagnosis*; D014402:Tuberous Sclerosis / Q000150:complications / Q000175:diagnosis*; D014463:Ultrasonography