title: [A single evening dose of 300 mg ranitidine in the treatment of acute attacks of gastric and duodenal ulcers. Evaluation of 1,208 patients].
abstract: The aim of this study was to evaluate, on a wide population of outpatients, the efficacy of ranitidine 300 mg given once a day at bedtime in duodenal and gastric ulcer. Healing rates observed on 1,208 patients were 85.2% (703/825) in duodenal ulcer, 79.5% (268/337) in gastric ulcer and 71.7% (33/46) in double localization, duodenal and gastric. Analysis of predictive factors of treatment failure showed no influence of smoking on the efficacy of ranitidine neither in duodenal nor gastric ulcer.
authors.affiliation: Sce d'Hépato-Gastroentérologie, Hôpital Saint-Eloi, Montpellier.
authors.forename: P
authors.initials: P
authors.lastname: Bories
authors.forename: J M
authors.initials: JM
authors.lastname: Tournade
authors.forename: B
authors.initials: B
authors.lastname: Alberola
authors.forename: M
authors.initials: M
authors.lastname: Pappo
mesh_terms: D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage; D002986:Clinical Trials as Topic; D004334:Drug Administration Schedule; D004381:Duodenal Ulcer / Q000188:drug therapy*; D004384:Duodenoscopy; D005260:Female; D005773:Gastroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D011899:Ranitidine / Q000008:administration & dosage / Q000627:therapeutic use*; D013276:Stomach Ulcer / Q000188:drug therapy*; D014945:Wound Healing
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D011899:Ranitidine
vernacular_title: Prise unique vespérale de 300 mg de ranitidine dans le traitement d'attaque des ulcères gastrique et duodénal en poussée. Evaluation chez 1,208 patients.