Ketoprofen in dentistry: a pharmacologic review.
The pharmacology, clinical dental studies, and the relevance to dental applications of ketoprofen, a recent addition to the group of nonsteroidal anti-inflammatory drugs, are reviewed. In addition to inhibiting the formation of prostaglandins, ketoprofen may also suppress leukotrienes and further limit inflammation. Clinically, it appears that ketoprofen compares favorably with many of the nonsteroidal drugs now in use. Recently approved for use in mild to moderate pain, ketoprofen's rapid onset of action, patent analgesic properties, and minimal side effects are particularly appealing.
Cailleteau
J G
JG
Department of Endodontics, University of Texas Dental Branch, Houston.
D006801:Humans; D007660:Ketoprofen / Q000493:pharmacokinetics / Q000494:pharmacology*; D010149:Postoperative Pain / Q000517:prevention & control; D010666:Phenylpropionates / Q000494:pharmacology*
D010666:Phenylpropionates; D007660:Ketoprofen