[Surveillance of renal transplantation in children].
A strict medical monitoring is necessary to ensure the long-term success of renal transplantation, in order to detect the occurrence of rejection, of possible complications, and of side-effects of drugs. This monitoring should be based on 1) clinical data, mainly measurement of blood pressure and graft palpation, 2) biological data, basically blood creatinine and urea, detection of proteinuria and of urinary tract infection, and blood count, 3) radiological data, principally graft ultrasonography, which should be done as soon as rejection or local complications are suspected, and 4) histopathological assessment, by fine-needle aspiration allowing cytological study, or, above all, graft biopsy, searching for rejection, cyclosporine nephrotoxicity, or transplant glomerulopathy. The interval between these controls, very short during the first months, can become longer with time, but a medical surveillance must be maintained throughout the graft survival.
Gagnadoux
M F
MF
Service de Néphrologie Pédiatrique, Hôpital des Enfants-Malades, Paris.
Habib
R
R
D005500:Follow-Up Studies; D006084:Graft Rejection; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging / Q000473:pathology; D016030:Kidney Transplantation; D011182:Postoperative Care / Q000592:standards*; D011183:Postoperative Complications / Q000378:metabolism / Q000517:prevention & control; D011859:Radiography
Surveillance des transplantations rénales chez l'enfant.