title: Serial stereotactic biopsy of brain stem expanding lesions. Considerations on 45 consecutive cases.
abstract: Fourty-five patients affected by brain stem expanding lesions underwent serial stereotactic biopsy between 1978 and 1986. The definitive histological diagnosis allowed the definitive treatment of extrinsic tumours and non-neoplastic lesions. In patients affected from glial tumours the serial stereotactic biopsy allowed the histological grading and the definition of the growth modalities at the superior boundaries of the tumours. These data have been utilized to guide the choice of treatment. The future perspectives of stereotactic biopsies are discussed in view of the therapeutic results obtained in this series and in other series reported in the literature.
authors.affiliation: Department of Neurosurgery, Istituto Neurologico C. Besta, Milano, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Franzini
authors.forename: A
authors.initials: A
authors.lastname: Allegranza
authors.forename: A
authors.initials: A
authors.lastname: Melcarne
authors.forename: C
authors.initials: C
authors.lastname: Giorgi
authors.forename: S
authors.initials: S
authors.lastname: Ferraresi
authors.forename: G
authors.initials: G
authors.lastname: Broggi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001254:Astrocytoma / Q000473:pathology* / Q000601:surgery; D001706:Biopsy / Q000379:methods*; D001927:Brain Diseases / Q000473:pathology*; D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery; D001933:Brain Stem / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013238:Stereotaxic Techniques