title: The Roswell Park Memorial Institute and Gastrointestinal Tumor Study Group phase III experience with the modulation of 5-fluorouracil by leucovorin in metastatic colorectal adenocarcinoma.
authors.affiliation: Roswell Park Memorial Institute, Department of Surgical Oncology, Buffalo, NY.
authors.forename: N J
authors.initials: NJ
authors.lastname: Petrelli
authors.forename: Y M
authors.initials: YM
authors.lastname: Rustum
authors.forename: H
authors.initials: H
authors.lastname: Bruckner
authors.forename: D
authors.initials: D
authors.lastname: Stablein
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D015179:Colorectal Neoplasms / Q000188:drug therapy*; D003967:Diarrhea / Q000139:chemically induced; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D007970:Leukopenia / Q000139:chemically induced; D008727:Methotrexate / Q000008:administration & dosage; D011897:Random Allocation; D013921:Thrombocytopenia / Q000139:chemically induced
chemical_list: D002955:Leucovorin; D005472:Fluorouracil; D008727:Methotrexate