[Tetracycline resistance and beta-lactamase production in pharyngeal commensal Neisseria].
Commensal Neisseria may constitute a potential source of resistance genes transferable to pathogenic Neisseria. We tested 150 strains of commensal Neisseria isolated from throat cultures for resistance to tetracycline and beta-lactamase production. Seven strains were high level tetracycline resistant (MIC greater than 16 mg/ml), and minocycline resistant. Only one strain carries a 40 kilobases plasmid. Seven strains were tetracycline resistant (MIC = 8 or 16 mg/l) and minocycline susceptible. Three strains were beta-lactamase producers. These strains were identified as Neisseria perflava or Neisseria sica.
Prère
M F
MF
CHU Toulouse Purpan.
Paillisson
J
J
Guibourdenche
M
M
Riou
J Y
JY
D006801:Humans; D066298:In Vitro Techniques; D008911:Minocycline / Q000494:pharmacology; D009343:Neisseria / Q000187:drug effects* / Q000201:enzymology / Q000302:isolation & purification; D010614:Pharynx / Q000382:microbiology; D011815:R Factors; D013753:Tetracycline Resistance / Q000235:genetics; D001618:beta-Lactamases / Q000096:biosynthesis*
D001618:beta-Lactamases; D008911:Minocycline
Resistance à la tétracycline et production de bêtalactamase chez les Neisseria commensales pharyngées.