title: EEG sleep and the cholinergic REM induction test in anorexic and bulimic patients.
abstract: The electroencephalographic (EEG) sleep of 20 anorexic patients, 10 bulimic patients, and 10 age-matched healthy controls was studied. In addition, six anorexic patients and six bulimic patients had a cholinergic rapid eye movement (REM) sleep induction test (RIT) performed with the cholinergic agent RS 86. The three samples showed no major differences in sleep patterns. The same held true when attention was focused on patients who additionally met DSM-III criteria for major depression. The RIT results were similar in the patients with eating disorders and in controls, but differed from those reported in depressives. Therefore, the present study found no hints of depression-like sleep patterns in patients with eating disorders.
authors.affiliation: Department of Psychiatry, University of Freiburg, Freiburg, FRG.
authors.forename: C
authors.initials: C
authors.lastname: Lauer
authors.forename: J
authors.initials: J
authors.lastname: Zulley
authors.forename: J C
authors.initials: JC
authors.lastname: Krieg
authors.forename: D
authors.initials: D
authors.lastname: Riemann
authors.forename: M
authors.initials: M
authors.lastname: Berger
mesh_terms: D000328:Adult; D000856:Anorexia Nervosa / Q000503:physiopathology*; D002032:Bulimia / Q000503:physiopathology*; D002540:Cerebral Cortex / Q000503:physiopathology; D002986:Clinical Trials as Topic; D003866:Depressive Disorder / Q000503:physiopathology; D004311:Double-Blind Method; D004569:Electroencephalography; D005071:Evoked Potentials / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D011897:Random Allocation; D011930:Reaction Time / Q000502:physiology; D012894:Sleep Stages / Q000502:physiology*; D012895:Sleep, REM / Q000502:physiology*; D013388:Succinimides
chemical_list: D013388:Succinimides; C001886:2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione