title: [Determination of the lethal phase in homo- and heterozygotes for a dominant lethal cold-sensitive mutation of Drosophila melanogaster at permissive temperature].
abstract: The lethal phase in homo- and heterozygotes for dominant cold-sensitive lethal mutation 1(2)M66DCS at permissive temperature (25 degrees C) was determined. The effective lethal phase was only revealed for homozygotes. 100% of them died during the first larval instar. In heterozygotes the mutation under study proved to be aphasic semi-lethal with 31.9% penetrance. It was localized on the left arm of chromosome 2, in position 51.2. The penetrance of some other phenotypes caused in heterozygotes at 25 degrees C was also studied.
authors.forename: M V
authors.initials: MV
authors.lastname: Generalova
authors.forename: E N
authors.initials: EN
authors.lastname: Miasniankina
mesh_terms: D000818:Animals; D003080:Cold Temperature; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D005799:Genes, Dominant; D005804:Genes, Lethal; D006579:Heterozygote; D006720:Homozygote; D008297:Male; D009154:Mutation
vernacular_title: Opredelenie letal'noĭ fazy u gomo- i geterozigot po dominantnoĭ letal'noĭ kholodochuvstvitel'noĭ mutatsii Drosophila melanogaster pri permessivnoĭ temperature.