Somatostatin analogue SMS 201-995 in the short-term management of neonatal hyperinsulinism due to nesidioblastosis.
A neonate with persistent hyperinsulinaemic hypoglycaemia is presented in whom the use of intravenous somatostatin SMS 201-995 allowed good glycaemic control over 10 days. A 95% pancreatectomy was then performed.
Sullivan
M J
MJ
Department of Paediatrics, University of Otago Medical School, Dunedin, New Zealand.
Taylor
B J
BJ
Broadbent
R S
RS
Yun
K
K
Lovell-Smith
M
M
Donald
R A
RA
D001786:Blood Glucose / Q000378:metabolism; D006801:Humans; D006946:Hyperinsulinism / Q000188:drug therapy* / Q000473:pathology; D007003:Hypoglycemia / Q000188:drug therapy; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D007515:Islets of Langerhans / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D015282:Octreotide / Q000627:therapeutic use*; D010179:Pancreas / Q000473:pathology; D010180:Pancreatectomy; D010182:Pancreatic Diseases / Q000150:complications* / Q000473:pathology / Q000601:surgery; D011183:Postoperative Complications / Q000188:drug therapy
D001786:Blood Glucose; D015282:Octreotide