A preliminary study of the changes in the direct-acting mutagenicities of several nitropolycyclic aromatic hydrocarbons after exposure under sunlight.
Five commercially available nitropolyclyclic aromatic hydrocarbons (nitro-PAH), namely, 4-nitrobiphenyl, 2-nitrofluorene, 9-nitroanthracene, 1-nitropyrene, and 2,7-dinitrofluorene, were exposed under restricted sunlight in the open air. The direct-acting mutagenicities of the samples after an exposure of 45 days were measured in order to compare them with those of the original samples in the Ames Salmonella typhimurium bioassay. It was found that the mutagenicities of some nitro-PAH do not change significantly while the mutagenicities of others increase or decrease after exposure. A preliminary study of nitro-PAH reaction products after exposure using GC, GC/MS, and FT-IR is also reported.
Xu
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XB
Institute of Environmental Chemistry, Academia Sinica, Beijing, China.
Zhao
L X
LX
Li
Y Q
YQ
He
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YL
D000873:Anthracenes / Q000633:toxicity; D001713:Biphenyl Compounds / Q000633:toxicity; D002849:Chromatography, Gas; D005449:Fluorenes / Q000633:toxicity; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D009152:Mutagenicity Tests; D009574:Nitro Compounds / Q000528:radiation effects / Q000633:toxicity*; D011083:Polycyclic Compounds / Q000528:radiation effects / Q000633:toxicity*; D011721:Pyrenes / Q000633:toxicity; D012486:Salmonella typhimurium / Q000187:drug effects* / Q000235:genetics; D013055:Spectrophotometry, Infrared; D013472:Sunlight
D000873:Anthracenes; D001713:Biphenyl Compounds; D005449:Fluorenes; D009574:Nitro Compounds; D011083:Polycyclic Compounds; D011721:Pyrenes; C019499:2-nitrofluorene; C035016:9-nitroanthracene; C040438:4-nitrobiphenyl; C032668:1-nitropyrene