Captopril in heart failure.
The renin production, angiotensin II and aldosterone plasma levels have been proved to occur in heart failure. This pathological abnormalities can be stopped by the inhibition of ACE. This action of captopril is accompanied by a favourable clinical effects, the improvement of the symptoms of heart failure and the increase of sodium and water excretion and the increase of serum potassium level.
Kékes
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Second Medical Department (Cardiology), Postgraduate Medical School, Budapest, Hungary.
D001696:Biomechanical Phenomena; D002216:Captopril / Q000008:administration & dosage / Q000627:therapeutic use*; D002303:Cardiac Output, Low / Q000188:drug therapy* / Q000503:physiopathology; D002986:Clinical Trials as Topic; D004334:Drug Administration Schedule; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans
D002216:Captopril