title: A northern California Oncology Group randomized trial of single agent 5-FU vs. high-dose folinic acid + 5-FU vs. methotrexate + 5-FU + folinic acid in patients with disseminated measurable large bowel cancer.
authors.affiliation: UC San Francisco, San Joaquin Valley CCOP, UC Davis.
authors.forename: F H
authors.initials: FH
authors.lastname: Valone
authors.forename: P S
authors.initials: PS
authors.lastname: Wittlinger
authors.forename: M S
authors.initials: MS
authors.lastname: Flam
authors.forename: T
authors.initials: T
authors.lastname: Drakes
authors.forename: P D
authors.initials: PD
authors.lastname: Eisenberg
authors.forename: J
authors.initials: J
authors.lastname: Hannigan
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011897:Random Allocation
chemical_list: D002955:Leucovorin; D005472:Fluorouracil; D008727:Methotrexate