[Comparative effects of pentoxifylline and of HWA 285 on mitochondrial maturation and biosynthesis of proteins in rats in the perinatal period].
To improve our understanding of the beneficial effects of alkylxanthines in various disorders, two animal models were used. The biochemical modifications due to pentoxifylline and HWA 285 on mitochondrial maturation and protein biosynthesis during the neonatal period were determined simultaneously.
Gautheron
D C
DC
LBTM-CNRS, Université Claude Bernard de Lyon, Villeurbanne, France.
Comte
J
J
Meister
R
R
Godinot
C
C
D000818:Animals; D000831:Animals, Newborn; D005947:Glucose / Q000494:pharmacology; D008099:Liver / Q000378:metabolism; D008930:Mitochondria, Liver / Q000187:drug effects* / Q000378:metabolism; D010085:Oxidative Phosphorylation / Q000187:drug effects; D010431:Pentoxifylline / Q000494:pharmacology*; D014176:Protein Biosynthesis; D051381:Rats; D013805:Theobromine / Q000031:analogs & derivatives*; D014970:Xanthines / Q000494:pharmacology*
D014970:Xanthines; C032114:propentofylline; D005947:Glucose; D013805:Theobromine; D010431:Pentoxifylline
Effets comparés de la pentoxifylline et du HWA 285 sur la maturation mitochondriale et la biosynthèse des protéines chez le rat dans la période périnatale.