[Endocrinological and metabolic disorders in the patients with massive bowel resection in the newborn period].
Massive (70%) resection of the small bowel was performed in seven newborn infants. Follow-up study was undertaken in four of these patients and the growth and endocrinological status were evaluated. Body weight and height of three patients were below 50th percentile. On glucose tolerance test, peak IRI was low and insulinogenic indices were below normal range. These findings suggest that there are some mechanisms which suppress the secretion of insulin. Pituitary and thyroid function were within normal limits but secondary sexual manifestation was not seen in a fifteen year old boy. Hyperoxaluria was seen in three children, and one had kidney stone with some impairment of renal function.
Kamagata
S
S
Department of Surgery and Pediatrics, Tokyo Metropolitan Kiyose Children's Hospital, Japan.
Ishida
H
H
Hayashi
A
A
Sambommatsu
T
T
Kanto
K
K
Matsufuji
H
H
Cho
H
H
D000293:Adolescent; D001827:Body Height; D001835:Body Weight; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007328:Insulin / Q000378:metabolism; D000078790:Insulin Secretion; D007421:Intestine, Small / Q000601:surgery*; D007668:Kidney / Q000502:physiology; D008297:Male; D010070:Oxalates / Q000652:urine; D010902:Pituitary Gland / Q000502:physiology; D012741:Sexual Maturation; D013961:Thyroid Gland / Q000502:physiology
D007328:Insulin; D010070:Oxalates