title: [The value of antibiotic prophylaxis using cefotetan in high-risk abdominal hysterectomy. Apropos of a prospective randomized study of 71 patients].
abstract: The advantage of antibiotic prophylaxis using a single dose of 2 g of cefotetan, administered during the induction of anesthesia, was studied in 71 patients undergoing an abdominal hysterectomy and presenting at least one of the following risk factors: obesity or procedure exceeding two hours. After random selection, 33 patients were treated, 38 were not and constitute the reference group. Comparison between the two groups shows a significant difference concerning the general morbidity, post-operative fever, urinary infection and abdominal wall abscess. Considering the excellent tolerance of the treatment and the fact that it is easy to use and inexpensive, antibiotic prophylaxis with cefotetan is quite interesting for this type of surgery.
authors.affiliation: Service de Gynécologie-Obstétrique, Hôpital Lariboisière, Université Paris VII.
authors.forename: N
authors.initials: N
authors.lastname: Ciraru-Vigneron
authors.forename: P
authors.initials: P
authors.lastname: Engelman
authors.forename: G
authors.initials: G
authors.lastname: Bercau
authors.forename: E
authors.initials: E
authors.lastname: Sauvanet
authors.forename: C
authors.initials: C
authors.lastname: Bitton
mesh_terms: D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000517:prevention & control; D015313:Cefotetan / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D009765:Obesity / Q000150:complications; D011292:Premedication; D011446:Prospective Studies; D011897:Random Allocation; D012307:Risk Factors
chemical_list: D015313:Cefotetan
vernacular_title: Intérêt de l'antibioprophylaxie par le cefotetan dans les hystérectomies abdominales à risques. A propos d'une étude prospective par tirage au sort portant sur 71 patientes.