Prenatal detection of a neural tube defect after fetal exposure to valproic acid.
Fetal exposure to valproic acid has recently been associated with an increased incidence of neural tube defects. The prenatal detection of a fetus with both hydrocephalus and meningomyelocele after valproic acid exposure is presented and specific recommendations made for antepartum evaluation in future pregnancies.
Weinbaum
P J
PJ
Cassidy
S B
SB
Vintzileos
A M
AM
Campbell
W A
WA
Ciarleglio
L
L
Nochimson
D J
DJ
D000032:Abortion, Therapeutic; D000293:Adolescent; D004827:Epilepsy / Q000150:complications / Q000188:drug therapy; D005260:Female; D005315:Fetal Diseases / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D006849:Hydrocephalus / Q000139:chemically induced / Q000175:diagnosis; D008591:Meningomyelocele / Q000139:chemically induced / Q000175:diagnosis; D009436:Neural Tube Defects / Q000139:chemically induced* / Q000175:diagnosis; D011247:Pregnancy; D011248:Pregnancy Complications; D011296:Prenatal Diagnosis; D014635:Valproic Acid / Q000009:adverse effects* / Q000627:therapeutic use
D014635:Valproic Acid