[Presenile dementia (Creutzfeldt-Jakob disease). Clinical and experimental data on a newly reported case].
A newly recorded case of presenile dementia (Creutzfeldt-Jakob disease) is discussed. The disease is experimentally transmissible to guinea pigs, after a long incubation period. From a pathomorphological point of view the experimental disease in the guinea pig is characterized by spongiosis, proliferative glial reaction, disappearance of neurons and of Purkinje's cells.
Drăgănescu
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N
Institut de Virologie Stefan S. Nicolau, Bucarest, Roumanie.
D000818:Animals; D001921:Brain / Q000473:pathology; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis / Q000473:pathology* / Q000635:transmission; D004569:Electroencephalography; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D008875:Middle Aged
La démence présénile (maladie de Creutzfeldt-Jakob). Données cliniques et expérimentales sur un nouveau cas enregistré.