title: Ultrasonographic prenatal diagnosis and fetal pathology of Langer mesomelic dwarfism.
abstract: In a family at risk for Langer mesomelic dwarfism, we document the onset of disproportionate growth in the second trimester by sonographic biometry. Midtrimester pathologic correlation of this condition demonstrates primary changes in the growthplate in the regions of proliferating cartilage and hypertrophic and degenerative chondrocytes.
authors.affiliation: Department of Obstetrics and Gynecology, Hutzel Hospital/Wayne State University, Detroit, Michigan 48201.
authors.forename: M I
authors.initials: MI
authors.lastname: Evans
authors.forename: I E
authors.initials: IE
authors.lastname: Zador
authors.forename: F
authors.initials: F
authors.lastname: Qureshi
authors.forename: H
authors.initials: H
authors.lastname: Budev
authors.forename: M H
authors.initials: MH
authors.lastname: Quigg
authors.forename: H L
authors.initials: HL
authors.lastname: Nadler
mesh_terms: D000328:Adult; D004392:Dwarfism / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis* / Q000473:pathology; D005820:Genetic Testing; D006801:Humans; D010009:Osteochondrodysplasias / Q000175:diagnosis* / Q000473:pathology; D010375:Pedigree; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014463:Ultrasonography; D014986:Xeroradiography