title: [Immunochemical analysis in research on antibodies to Streptococcus group A ribosomes].
abstract: The use of the competitive enzyme immunoassay (EIA) has made it possible to demonstrate that antiserum to the ribosomes of group A streptococcus, type 29 M, contains antibodies to homologous protein M and does not contain antibodies to group A polysaccharide, lipoteichoic acid and peptidoglycan. Ribosomal antiserum has been found to bind with the surface of heterologous type M streptococci in EIA, while forming no precipitation lines with heterologous proteins M in the double immunodiffusion test, which indicates that the binding of ribosomal antibodies with the surface of group A streptococcal cells is not type-specific. Antibodies to the ribosomes of group A streptococcus recognize some of the antigenic determinants of E. coli ribosomes.
authors.forename: A R
authors.initials: AR
authors.lastname: Shikhman
authors.forename: L V
authors.initials: LV
authors.lastname: Nikolaeva
authors.forename: O A
authors.initials: OA
authors.lastname: Kondrakova
authors.forename: E P
authors.initials: EP
authors.lastname: Savel'ev
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis*; D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins / Q000276:immunology; D001666:Binding Sites, Antibody; D001667:Binding, Competitive; D002352:Carrier Proteins; D002473:Cell Wall / Q000276:immunology; D003429:Cross Reactions; D004926:Escherichia coli / Q000276:immunology; D007114:Immunization; D005779:Immunodiffusion; D007124:Immunoenzyme Techniques; D011817:Rabbits; D012270:Ribosomes / Q000276:immunology*; D013297:Streptococcus pyogenes / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D002352:Carrier Proteins; C014689:streptococcal M protein
vernacular_title: Immunokhimicheskiĭ analiz v issledovaniiakh antitel k ribosomam streptokokka gruppy A.