Deficient release of prostacyclin-like activity by rat stomach under stress.
It is known that a confinement procedure will promote histological alterations in the gastric mucosa of rats. It is our hypothesis that, under these conditions, there should be an alteration in prostacyclin metabolism. Our findings corroborate this idea, which makes us suppose that the deficient release of prostacyclin-like activity by the rat's stomach may play an important role in gastric mucosa vitality and in its consequent damage.
Chamone
D A
DA
Brazilian Institute for Studies and Research in Gastroenterology, Department of Internal Medicine, Medical School of Sorocaba, São Paulo.
Massumoto
C M
CM
Paschôa
A F
AF
Arashiro
F
F
Pontes
J F
JF
D000818:Animals; D011464:Epoprostenol / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism* / Q000473:pathology; D008297:Male; D010974:Platelet Aggregation; D051381:Rats; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000378:metabolism*
D011464:Epoprostenol