Position of Igl-1, md, and Bst loci on chromosome 16 of the mouse.
The experiments described here delineate the position of the chromosome 16 markers Igl-1 (immunoglobulin lambda 1, light chain), md (mahoganoid), and Bst (belly spot and tail), and suggest their location relative to the endogenous proviral locus Akv-2, which is linked within 5.9 centimorgans to Igl-1 (Epstein et al. 1984). The data from an intercross and a three-point backcross detailed herein show the order of these three genes and distances between them to be: centromere-md-10.4 +/- 1.6-Igl-1-15.6 +/- 2.6-Bst. Using a recombinant chromosome recovered in the intercross, we have constructed a stock homozygous for md and Igl-1b (KpnI-), that will aid in mapping other genes on chromosome 16.
Epstein
R
R
Davisson
M
M
Lehmann
K
K
Akeson
E C
EC
Cohn
M
M
D000406:AKR murine leukemia virus / Q000235:genetics; D000818:Animals; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D005260:Female; D008040:Genetic Linkage; D006200:Hair Color; D007147:Immunoglobulin Light Chains / Q000235:genetics*; D007146:Immunoglobulin lambda-Chains / Q000235:genetics*; D008297:Male; D051379:Mice / Q000235:genetics*; D008810:Mice, Inbred C57BL / Q000235:genetics; D010860:Pigments, Biological / Q000235:genetics*
D007147:Immunoglobulin Light Chains; D007146:Immunoglobulin lambda-Chains; D010860:Pigments, Biological