title: Augmented postprandial gastric acid secretion due to exposure to ranitidine in healthy subjects.
abstract: In 10 healthy volunteers gastric acid output in response to a meal was significantly increased 60-64 h after cessation of 4 weeks of ranitidine treatment as compared with the response before treatment. Four to 6 weeks after discontinuation of treatment the acid secretory response to the meal had returned to values not significantly different from those seen before treatment. There was no change in pepsin output owing to ranitidine treatment.
authors.forename: K
authors.initials: K
authors.lastname: Frislid
authors.forename: E
authors.initials: E
authors.lastname: Aadland
authors.forename: A
authors.initials: A
authors.lastname: Berstad
mesh_terms: D000328:Adult; D005260:Female; D005502:Food; D005744:Gastric Acid / Q000378:metabolism*; D006801:Humans; D008297:Male; D010434:Pepsin A / Q000378:metabolism; D011899:Ranitidine / Q000494:pharmacology*; D013997:Time Factors
chemical_list: D011899:Ranitidine; D010434:Pepsin A