[A prospective randomized study on the fractionation of afterloading therapy of cancer of the cervix and endometrium].
A prospective randomized clinical study is made on patients with uterine cervix and endometrium carcinomas treated only by radiotherapy. The fractionation schemes of 4 times 10 Gy, and 5 times 8 Gy, and 8 times 5 Gy at the reference points A and My, respectively, of a short-term afterloading therapy combined with percutaneous telecobalt therapy with 45 Gy at the pelvic wall are investigated. A tendency is shown towards better tumor control and less radiogenic effects with an increased number of fractions. The results are discussed on the basis of the NSD and LQ models. The problems caused by the equipment type and dosage specificity hampering the applicability of the results on other afterloading therapy units are pointed out.
Kob
D
D
Klinik und Poliklinik für Radiologie des Bereiches Medizin der Friedrich-Schiller-Universität Jena.
Kloetzer
K H
KH
Kriester
A
A
Sommer
H
H
D000368:Aged; D001918:Brachytherapy / Q000379:methods*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D011879:Radiotherapy Dosage; D011897:Random Allocation; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*; D014594:Uterine Neoplasms / Q000532:radiotherapy*
Prospektive randomisierte Studie zur Fraktionierung der Afterloading-Therapie von Zervix- und Endometriumkarzinomen.