Heparin therapy, deep-vein thrombosis and pulmonary embolism after intracerebral hemorrhage.
A prospective randomized pilot study of subcutaneous low-dose heparin in the prevention of deep-vein thrombosis and pulmonary embolism was carried out in patients admitted to hospital after intracerebral hemorrhage. A high incidence of deep-vein thrombosis and lung embolism was detected by phleboscintigraphy and lung perfusion scintigraphy, respectively. There was no significant reduction of deep-vein thrombosis and pulmonary embolism in the therapy group. Heparin did not increase the risk of rebleeding.
Dickmann
U
U
Neurologische Klinik, Universität Göttingen.
Voth
E
E
Schicha
H
H
Henze
T
T
Prange
H
H
Emrich
D
D
D002543:Cerebral Hemorrhage / Q000139:chemically induced / Q000150:complications*; D002986:Clinical Trials as Topic; D004305:Dose-Response Relationship, Drug; D005260:Female; D006493:Heparin / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000517:prevention & control*; D012008:Recurrence; D013924:Thrombophlebitis / Q000517:prevention & control*
D006493:Heparin