[Sensitivity of Campylobacter to 2 new groups of beta-lactams].
One hundred strains of Campylobacter (44 C. jejuni, 34 C. coli, and 22 C. fetus ssp. fetus) were tested with two new groups of beta-lactams:monobactams (azthreonam and carumonam) and carbapenem (imipenem). MICs were determined by using an agar dilution technique. The monobactams were not effective against Campylobacter species. In contrast, imipenem showed a high activity (MIC 90, 0.25 mg/l). Clinical trials will indicate if this compound can be used in the therapy of severe Campylobacter infections.
Belbouri
A
A
Laboratoire de Bacteriologie, Hôpital des Enfants, Bordeaux.
Novo
Y
Y
Megraud
F
F
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002167:Campylobacter / Q000187:drug effects*; D002169:Campylobacter Infections / Q000188:drug therapy; D002168:Campylobacter fetus / Q000187:drug effects; D006801:Humans; D015378:Imipenem / Q000494:pharmacology; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests
D000900:Anti-Bacterial Agents; D015378:Imipenem
Sensibilité des Campylobacters à deux nouveaux groupes de bêtalactamines.