title: [Vaccination of ferrets (Putorius furo) against rabies using a tissue vaccine].
abstract: The use of live tissue rabies vaccine from Vnukovo-32 strain produced by the Bioveta National Corporation at Ivanovice na Hané was tested on 15 ferrets (Putorius furo L. 1758). The 21st day after subcutaneous application of 3 ml of vaccine, the average titre of virus-neutralizing antibodies was 1 : 71.4, and after subcutaneous and intramuscular application of 1 ml of vaccine the average titre was 1:20.6 and 1 : 15.6, respectively. The challenge test was performed 52 weeks after vaccination: a dose of 10(5) MICLD50 of the street rabies virus was applied i. m. to the neck muscle. All the vaccinated animals survived. As indicated by the results of the trials, a good tolerance and full immunity of vaccinates to the infection with the street rabies virus was maintained for one year. 1 ml of vaccine diluted according to instructions and applied s. c. or i. m. was found to be sufficient.
authors.forename: O
authors.initials: O
authors.lastname: Matouch
authors.forename: J
authors.initials: J
authors.lastname: Dousek
mesh_terms: D000818:Animals; D002335:Carnivora; D005260:Female; D005289:Ferrets; D008297:Male; D011818:Rabies / Q000517:prevention & control / Q000662:veterinary*; D011819:Rabies Vaccines; D014611:Vaccination / Q000662:veterinary*
chemical_list: D011819:Rabies Vaccines
vernacular_title: Vakcinace fretek (Putorius furo) proti vzteklinĕ tkánovou vakcínou.