Induction of beta-lactamases.
Inducible beta-lactamases can significantly affect the activities of both beta-lactamase-stable and beta-lactamase-sensitive antibiotics. beta-Lactam antibiotics vary in their ability to induce beta-lactamases. Strong inducers can antagonize the antimicrobial activity of other beta-lactams.
Eliopoulos
G M
GM
Department of Medicine, New England Deaconess Hospital, Harvard Medical School, Boston, Massachusetts 02215.
D001419:Bacteria / Q000201:enzymology*; D004352:Drug Resistance, Microbial; D004790:Enzyme Induction; D001618:beta-Lactamases / Q000096:biosynthesis*
D001618:beta-Lactamases