Sex differences in drug conjugation and their consequences for drug toxicity. Sulfation, glucuronidation and glutathione conjugation.
Mulder
G J
GJ
D000818:Animals; D001692:Biological Transport; D001711:Biotransformation; D002273:Carcinogens / Q000378:metabolism; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D005965:Glucuronates / Q000378:metabolism*; D014453:Glucuronosyltransferase / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism*; D005982:Glutathione Transferase / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D008099:Liver / Q000201:enzymology / Q000378:metabolism; D008297:Male; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D010724:Phosphoadenosine Phosphosulfate / Q000378:metabolism; D051381:Rats; D012737:Sex Factors; D013379:Substrate Specificity; D013431:Sulfates / Q000378:metabolism*; D013466:Sulfurtransferases / Q000378:metabolism; D014535:Uridine Diphosphate Glucuronic Acid / Q000378:metabolism
D002273:Carcinogens; D005965:Glucuronates; D004364:Pharmaceutical Preparations; D013431:Sulfates; D014535:Uridine Diphosphate Glucuronic Acid; D010724:Phosphoadenosine Phosphosulfate; D014453:Glucuronosyltransferase; D005982:Glutathione Transferase; D013466:Sulfurtransferases; D005978:Glutathione