Immunocytochemical demonstration of vertebrate peptides in invertebrates: the homology concept.
During the last years many positive immunocytochemical reactions have been described in invertebrates using antisera to vertebrate regulatory peptides. However, due to the specificity problems associated with immunocytochemistry, the significance of the majority of these findings remains unclear, as so far only a few of the substances causing the immunoreactions in invertebrates have been isolated. It is proposed that comparing the localizations of "vertebrate" peptides in different and not closely related species of an invertebrate group may give a clue to the physiological relevance of the immunoreactive substances.
Veenstra
J A
JA
Department of Biological Organic Chemistry, C.S.I.C., Barcelona, Spain.
D000818:Animals; D007150:Immunohistochemistry; D010455:Peptides / Q000032:analysis*; D014714:Vertebrates
D010455:Peptides