Molecular genetic approaches to the pathogenesis of bacillary dysentery.
Bacillary dysentery is an invasive infectious disease of the human colon. At least three genetic loci on the chromosome and a huge plasmid have been implicated in its pathogenesis. Results obtained from molecular genetic studies, mainly of the genes, virG, virF and kcpA are discussed.
Yoshikawa
M
M
Institute of Medical Science, University of Tokyo, Japan.
Sasakawa
C
C
Makino
S
S
Okada
N
N
Lett
M C
MC
Sakai
T
T
Yamada
M
M
Komatsu
K
K
Kamata
K
K
Kurata
T
T
D000818:Animals; D002874:Chromosome Mapping; D004405:Dysentery, Bacillary / Q000209:etiology / Q000235:genetics*; D005798:Genes, Bacterial; D006801:Humans; D010957:Plasmids; D012760:Shigella / Q000235:genetics / Q000472:pathogenicity; D014774:Virulence / Q000235:genetics