[Genetic determinants of antibiotic resistance in gram negative bacteria].
Modern data on spreading, structural and functional organization and evolution of the genetic determinants of antibiotic resistance in the gram-negative bacteria are reviewed. Some mechanisms for resistance to trimethoprime, sulphonamides, tetracyclines, chloramphenicol aminoglycosides, beta-lactam antibiotics controlled by the plasmid and chromosomal genes are presented. The problem of using the molecular DNA-probes containing the genetical determinants for antibiotic resistance in the practical work of clinical laboratories is discussed.
Anisimova
L A
LA
Boronin
A M
AM
D004352:Drug Resistance, Microbial / Q000235:genetics*; D005798:Genes, Bacterial; D006090:Gram-Negative Bacteria / Q000235:genetics*; D010957:Plasmids
Geneticheskie determinanty rezistentnosti k antibiotikam gramotritsatel'nykh bakteriĭ.