title: Serous otitis media and immunological reactions in the middle ear mucosa.
abstract: An immunohistochemical study was performed on the middle ear mucosa of 21 children with chronic serous otitis media (SOM). In 86% of the patients a highly organized lymphatic tissue was found in the middle ear mucosa which can be regarded as part of the mucosa associated lymphoid tissue (MALT). Features of an immune complex mediated (type III) hypersensitivity reaction were absent.
authors.affiliation: Department of Otolaryngology/Head and Neck Surgery, Free University Hospital, Amsterdam, The Netherlands.
authors.forename: S
authors.initials: S
authors.lastname: van der Baan
authors.forename: C A
authors.initials: CA
authors.lastname: Seldenrijk
authors.forename: S C
authors.initials: SC
authors.lastname: Henzen-Logmans
authors.forename: H A
authors.initials: HA
authors.lastname: Drexhage
mesh_terms: D000328:Adult; D000936:Antigen-Antibody Complex / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D004432:Ear, Middle / Q000378:metabolism*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007124:Immunoenzyme Techniques; D008221:Lymphoid Tissue / Q000276:immunology* / Q000378:metabolism; D008875:Middle Aged; D009092:Mucous Membrane / Q000378:metabolism; D010034:Otitis Media with Effusion / Q000276:immunology* / Q000378:metabolism
chemical_list: D000936:Antigen-Antibody Complex