[Effects of isoptin and obsidan on the coronary blood flow and tactics in anti-angina therapy of patients with ischemic heart disease].
Single intravenous doses of isoptin (10 mg) and obsidan (5 mg) were tested for their effects on hemodynamic and coronary blood flow parameters in 35 patients with coronary heart disease and functional classes II-III angina pectoris of effort. In most cases, hemodynamic and coronary blood flow responses to the drug administered were found to be identical. It was concluded that isoptin was effective as an antianginal agent in eukinetic hemodynamics, obsidan, in hyperkinetic one.
Vakhliev
V D
VD
Bogatyrev
I V
IV
Uchaĭkina
L V
LV
Syrkin
A L
AL
D000328:Adult; D000787:Angina Pectoris / Q000188:drug therapy* / Q000503:physiopathology; D002121:Calcium Channel Blockers / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003326:Coronary Circulation / Q000187:drug effects*; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D011433:Propranolol / Q000008:administration & dosage / Q000627:therapeutic use*; D014700:Verapamil / Q000627:therapeutic use*
D002121:Calcium Channel Blockers; D011433:Propranolol; D014700:Verapamil
Vliianie izoptina i obzidana na koronarnyĭ krovotok i taktika antianginal'noĭ terapii u bol'nykh ishemicheskoĭ bolezn'iu serdtsa.