[Effect of inhibitors and cations on the proteolytic activity of Bacillus mesentericus].
The effect of some inhibitors and bivalent metal cations (Mn2+, Ca2+, Fe2+, Zn2+, Mg2+, Co2+ and Cu2+) on the proteolytic activity of two Bacillus mesentericus strains (strain 8 and strain 64 M-variant) was comparatively studied. The both enzymes were shown to be serine proteinases, but the proteinase of strain 64 was also a metal-dependent enzyme. Metal ions exerted no essential effect on the proteinase of strain 8. Ca2+ and Mg2+ ions stimulated the proteinase activity of strain 64 whereas Fe2+ and Zn2+ ions inhibited it in the case of three substrates. Therefore, the two proteinases are different.
Imshenetskiĭ
A A
AA
Nesterova
N G
NG
Cherkesova
G V
GV
Fetisova
Z S
ZS
D001230:Aspergillus / Q000187:drug effects / Q000201:enzymology; D001407:Bacillus / Q000187:drug effects* / Q000201:enzymology; D002412:Cations; D005342:Fibrinolysis / Q000187:drug effects; D006801:Humans; D008670:Metals / Q000494:pharmacology*; D010447:Peptide Hydrolases / Q000494:pharmacology; D011480:Protease Inhibitors / Q000494:pharmacology*
D002412:Cations; D008670:Metals; D011480:Protease Inhibitors; D010447:Peptide Hydrolases
Vliianie ingibitorov i nekotorykh kationov na proteoliticheskuiu aktivnost' Bacillus mesentericus.