title: [Effect of exogenous administration of steroids during the 1st month of pregnancy in sows and gilts on certain characteristics of the litter].
abstract: Four trials were performed to evaluate the influence of i. m. application of progesterone and estrogens to 444 experimental and control sows and gilts, kept mostly under large-scale production conditions, during the first month of pregnancy, as exerted on the number of born piglets, live born piglets and on the average birth weight of the live born piglet in litter. In the first trial the experimental sows and gilts on the 16th and 17th days of gravidity were applied 25 mg of progesterone (P4) and 12.5 micrograms of estrone (E1), in the second trial in the same phase of gravidity 25 mg of P4 with 1.25 micrograms of estradiol-17 beta (E2) and in the third trial in the identical gestation phase only 12.5 micrograms of E2 per head/day. In the fourth trial, experimental animals were given 0.55 mg of P4 with 0.275 micrograms of E1 per one kg of live weight, for six subsequent days between the 25th and 30th day of gravidity. In all trials the control animals were administered, under the same conditions, only the vehicle. None of the performed trials proved a significant difference in the studied parameters of litters of experimental and control animals (P greater than 0.05). The application of 25 mg of P4 with 1.25 micrograms of E2 on the 16th and 17th days of gravidity per sow/day under the conditions of small-scale production with the extension of the evaluated criteria of litter quality had no significant influence (P greater than 0.5) on the above-mentioned indicators, nor on the average birth weight of the whole litter and on the average number and weight of piglets of experimental sows at weaning. These results document that the verified application of hormonal substances in the above-mentioned phases of the first month of sow and gilt gravidity do not represent, in view of the intensive reproduction of pigs, a suitable procedure.
authors.forename: S
authors.initials: S
authors.lastname: Navrátil
authors.forename: M
authors.initials: M
authors.lastname: Manásková
authors.forename: M
authors.initials: M
authors.lastname: Stefan
mesh_terms: D000818:Animals; D001724:Birth Weight / Q000187:drug effects; D004970:Estrone / Q000494:pharmacology*; D005260:Female; D005313:Fetal Death / Q000662:veterinary*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*; D011374:Progesterone / Q000494:pharmacology*; D013552:Swine; D013997:Time Factors
chemical_list: D004970:Estrone; D011374:Progesterone
vernacular_title: Ucinek exogenního prívodu steroidů v prvním mĕsíci gravidity prasnic a prasnicek na nĕkteré charakteristiky vrhu selat.