title: Factor VIII complex in canine plasma after submaximal treadmill exercise.
abstract: Exercise-induced changes in the plasma concentrations of coagulation factor VIII and von Willebrand factor were evaluated, using 8 random-source adult dogs that exercised on a treadmill for 5 to 10 minutes (mean running time = 8.3 minutes). Maximum treadmill speeds attained by the dogs were 11 to 18 km/hr, and the mean of the maximum individual speeds was 14.3 km/hr. Maximum heart rates of individual dogs during exercise were 190 to 250 beats/min with a mean of 218 beats/min (a 2.4-fold increase over the mean preexercise rate). Exercise did not induce significant increases in plasma concentrations of factor VIII coagulant activity, coagglutinin co-factor activity, or factor VIII-related antigen. Results indicated that submaximal exercise does not induce increases in plasma concentrations of coagulation factor VIII or von Willebrand factor in the dog.
authors.forename: M A
authors.initials: MA
authors.lastname: Turrentine
authors.forename: A W
authors.initials: AW
authors.lastname: Hahn
authors.forename: G S
authors.initials: GS
authors.lastname: Johnson
mesh_terms: D000818:Animals; D000941:Antigens / Q000032:analysis; D037222:Collectins; D004285:Dogs; D005169:Factor VIII / Q000032:analysis* / Q000276:immunology; D008297:Male; D005082:Physical Exertion; D012712:Serum Globulins / Q000032:analysis; D014841:von Willebrand Factor / Q000032:analysis
chemical_list: D000941:Antigens; D037222:Collectins; D012712:Serum Globulins; C024014:conglutinin; D014841:von Willebrand Factor; D005169:Factor VIII