Gene expression in amphibian embryogenesis.
The study of molecular events during the embryogenesis of Xenopus laevis has advanced as a result of the availability of molecular markers, i.e., nucleic acid and antibody probes for genes that are expressed in a temporally and spatially regulated fashion during development. In this article we summarize results on the localized expression of keratin genes and on the reconstruction of regulated transcription of the gastrula/neurula-specific DG42 gene. Furthermore, we discuss experiments that investigate molecular events during mesoderm induction and provide information on the nature of the inducing principle.
Dawid
I B
IB
Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, Bethesda, MD 20892.
Rebbert
M L
ML
Rosa
F
F
Jamrich
M
M
Sargent
T D
TD
D000818:Animals; D002454:Cell Differentiation; D004627:Embryonic Induction; D005786:Gene Expression Regulation; D005819:Genetic Markers; D014982:Xenopus laevis / Q000196:embryology* / Q000378:metabolism
D005819:Genetic Markers