Hypertension in diabetes mellitus.
Hypertension, commonly associated with diabetes mellitus, plays a major role in the severity and progression of diabetic complications. The frequency and impact of hypertension on the course of diabetic nephropathy, and the role of persistent microalbuminuria either as a predictor of future overt diabetic nephropathy or as a marker of incipient hypertension is reviewed. The special considerations for antihypertensive agents in diabetes as well as the rationale for early intervention using a "substitution" rather than "stepped-care" approach are discussed.
Rosenstock
J
J
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas.
Raskin
P
P
D000419:Albuminuria / Q000209:etiology; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000652:urine; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy / Q000209:etiology