title: [Macrolides].
abstract: The first macrolides were marketed almost 30 years ago. These drugs constitute a homogeneous class of antibiotics with very similar mechanisms of action and resistance. Owing to their specific antibacterial spectrum and their mild side-effects, interest in macrolides has now been renewed, notably because of their activity against bacteria that develop within cells. Recent studies have provided additional information on their pharmacokinetic profiles, and notably on their tissue and intracellular distribution.
authors.affiliation: Service de Bactériologie, Hôpital de Bellevue.
authors.forename: G
authors.initials: G
authors.lastname: Aubert
mesh_terms: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use; D004352:Drug Resistance, Microbial; D006801:Humans
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents
vernacular_title: Macrolides.