title: Evidence for a predominant renal secretion and clearance of inactive plasma renin, studied by in vivo inhibition of protein synthesis, and inhibition of renal tubular protein reabsorption.
abstract: Inactive plasma renin is mainly secreted and eliminated by the kidneys in the mouse. The half-life of inactive plasma renin is 6 hours or less. The kidneys remove inactive renin from the circulation by glomerular ultrafiltration.
authors.affiliation: Institute of Biochemistry, Royal Dental College, Copenhagen N, Denmark.
authors.forename: A H
authors.initials: AH
authors.lastname: Nielsen
authors.forename: K L
authors.initials: KL
authors.lastname: Hermann
authors.forename: I
authors.initials: I
authors.lastname: Mazanti
authors.forename: K
authors.initials: K
authors.lastname: Poulsen
mesh_terms: D000042:Absorption; D000818:Animals; D004792:Enzyme Precursors / Q000097:blood* / Q000378:metabolism; D007668:Kidney / Q000378:metabolism*; D007684:Kidney Tubules / Q000378:metabolism*; D051379:Mice; D012083:Renin / Q000097:blood* / Q000378:metabolism
chemical_list: D004792:Enzyme Precursors; D012083:Renin