Lower motoneuron trophic factors and lower motoneuron death: effects and mechanisms.
The characterization of trophic factors for the survival of embryonic montoneurons in vitro is described. Current knowledge and experiments in progress are reported. It seems that trophic support for motoneurons is derived from all the cells which they contact during development.
Raju
T R
TR
Neurobiology Research Centre, University of Sydney, New South Wales, Australia.
Bennett
M R
MR
D000818:Animals; D002454:Cell Differentiation; D002470:Cell Survival; D002642:Chick Embryo; D009046:Motor Neurons / Q000166:cytology*; D009414:Nerve Growth Factors / Q000502:physiology*; D009419:Nerve Tissue Proteins / Q000502:physiology*; D013116:Spinal Cord / Q000166:cytology*
D009414:Nerve Growth Factors; D009419:Nerve Tissue Proteins