[Tumors of the nasal cavity in human immunodeficiency virus infection. A case of polyclonal lymphoid hyperplasia].
HIV virus infection is frequently accompanied by polyclonal or monoclonal lymphoid proliferations. The authors report the first case of a tumour of the cavum in a Haitian subject with HIV infection. This large tumour was associated with parotid swelling and a buccal and ocular sicca syndrome. Histological examination revealed Sjögren type of lympho-epithelial infiltration in the parotid and salivary glands. Biopsy of the cavum demonstrated lymphoid hyperplasia without a monoclonal component. There was no lymphoid proliferation outside of the ear, nose and throat region. The various benign and malignant lymphoid proliferations observed during HIV infection are recalled. Their pathophysiology is discussed: role of EBV in B cell lymphoid proliferations, specific cytotoxicity against cells infected by HIV in T8 proliferations.
Pulik
M
M
Unité d'Hématologie, Centre Hospitalier Victor Dupouy, Argenteuil.
Lida
H
H
Blanchereau
C
C
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D006679:HIV Seropositivity; D006801:Humans; D006965:Hyperplasia; D008232:Lymphoproliferative Disorders / Q000150:complications*; D008297:Male; D009296:Nasal Cavity; D009668:Nose Diseases / Q000150:complications; D012859:Sjogren's Syndrome / Q000150:complications*
Tumeur du cavum au cours de l'infection par le virus de l'immunodéficience humaine. Un cas d'hyperplasie lymphoïde polyclonale.