[Efficacy of intravenous sotalol in the treatment of supraventricular tachycardia].
20 patients with supraventricular tachycardia, received one to three intravenous injections of 0.5 mg/kg of sotalol. This group included 8 atrial fibrillations, 5 atrial flutters, 2 systolic tachycardias and 5 junctional tachycardias. Return to a normal sinus rhythm is obtained in 2 of the 8 patients with atrial fibrillation while a decreased heart rate under 100 per minute is noted in 3 of them. Among the 5 patients with atrial flutter, only one returned to a normal sinus rhythm and in 2 the tachycardia decreased. In the 2 patients with systolic tachycardia, the heart rate decreased without return to a normal sinus rhythm while the heart rate decreased in all 5 cases of junctional tachycardia. A left ventricular failure with hypotension, a bradycardia at 30/min. and a transient left bundle branch block were observed during treatment. The bundle branch block is explained by an increased ventricular effective, refractory period induced by this beta-blocker. Intravenous sotalol appears as an interesting alternative in the treatment of supraventricular tachycardias with an efficacy of about 70 p. cent; it is well tolerated if the contraindications of the beta-blockers are respected.
Denis
J
J
Service de Cardiologie, Centre Hospitalier Général, Saint-Nazaire.
Brunel
P
P
Moisan
A
A
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D013015:Sotalol / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D013617:Tachycardia, Supraventricular / Q000188:drug therapy*
D013015:Sotalol
Efficacité du sotalol intraveineux dans le traitement des tachycardies supraventriculaires.