Studies on fat emulsions in combined nutrition solutions.
The effect of added Aminoplex, Glucoplex, nutrient additives and calcium chloride on the stability of a fat emulsion (Intralipid) has been examined. The conclusions are as follows: Aminoplex and Glucoplex do not cause a decrease in the physical stability of mixed systems that contain fat droplets stored at room temperature for at least 7 days. The mixed systems are stable even in the presence of high electrolyte loads (greater than 600 mmol litre-1 expressed in terms of monovalent cation). The amino acids in Aminoplex could be having a stabilizing effect on the emulsion system by the adsorption of components to the oil/water interface.
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D004355:Drug Stability; D004356:Drug Storage; D004573:Electrolytes / Q000032:analysis; D004586:Electrophoresis; D005217:Fat Emulsions, Intravenous / Q000008:administration & dosage*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010288:Parenteral Nutrition; D010316:Particle Size; D013499:Surface Properties
D004573:Electrolytes; D005217:Fat Emulsions, Intravenous