title: Molecular analysis of a cytoplasmic factor essential for pole cell formation in Drosophila embryos.
abstract: This article reviews recent analytical studies of cytoplasmic factors involved in a mechanism underlying pole cell formation in Drosophila embryogenesis. Polar plasm, or germ plasm, includes sources of two independent functions in the germ-line segregation from the somatic line: pole cell formation and commitment of pole cells to germ cells. The UV-caused inability of pole cell formation in embryos was restored by poly(A)+ RNA, of which cDNA was cloned. The nucleotide sequence of the cDNA was highly homologous with mitochondrial large rRNA.
authors.affiliation: Institute of Biological Sciences, University of Tsukuba, Ibaraki, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: M
authors.initials: M
authors.lastname: Okada
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects*; D003593:Cytoplasm / Q000378:metabolism*; D004272:DNA, Mitochondrial / Q000378:metabolism; D004330:Drosophila / Q000196:embryology* / Q000378:metabolism; D004627:Embryonic Induction / Q000187:drug effects*; D008928:Mitochondria / Q000378:metabolism*; D009865:Oocytes / Q000378:metabolism* / Q000502:physiology
chemical_list: D004272:DNA, Mitochondrial