Epithelioid sarcoma with diffuse bone marrow metastases and associated leukemoid reaction. A case report and brief literature review.
A patient with a recurrent epithelioid sarcoma of the hand was observed for five years with a diagnosis of nodular fasciitis. Eventually, the patient had a pulmonary metastasis and diffuse bone marrow spread, which was associated with a leukemoid reaction. Bone marrow dissemination by sarcoma is unusual, and its production of a leukemoid reaction very rare; this is its first reported occurrence in epithelioid sarcoma that the authors have been able to identify in the literature.
Rosenberg
A E
AE
Department of Pathology, Harvard Medical School, Boston, Massachusetts.
Garber
J E
JE
Bennett
W
W
Bhan
A K
AK
Antman
K H
KH
Mark
E J
EJ
D000328:Adult; D001853:Bone Marrow; D001859:Bone Neoplasms / Q000473:pathology / Q000556:secondary*; D006225:Hand; D006801:Humans; D007955:Leukemoid Reaction / Q000473:pathology*; D008175:Lung Neoplasms / Q000556:secondary*; D008297:Male; D012509:Sarcoma / Q000473:pathology / Q000556:secondary*