In vitro response of Plasmodium falciparum to chloroquine and mefloquine in southeast Madagascar.
46 isolates of Plasmodium falciparum collected in the Tolagnaro (Fort Dauphin) area of Southeast Madagascar were assessed with WHO in vitro micro-technique test kits to determine their susceptibility to chloroquine and mefloquine. The results of the tests indicated low grade resistance to chloroquine and satisfactory response to mefloquine.
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D000818:Animals; D000962:Antimalarials / Q000494:pharmacology*; D002738:Chloroquine / Q000494:pharmacology*; D004351:Drug Resistance; D066298:In Vitro Techniques; D008270:Madagascar; D015767:Mefloquine; D010963:Plasmodium falciparum / Q000187:drug effects*; D011804:Quinolines / Q000494:pharmacology*
D000962:Antimalarials; D011804:Quinolines; D002738:Chloroquine; D015767:Mefloquine