Multiple primary tumours in oral cancer.
In 210 cases of oral cancer, 38 (17.6%) second primary tumours were found. Males had a higher chance of developing a second primary than females (21.4% versus 12%). The difference was not statistically significant (p = 0.11). When the index tumour was in the lower part of the oral cavity (floor of mouth, retromolar trigone, inferior alveolar process), a higher rate of second primaries was found than in cancer of the rest of the oral cavity (tongue, buccal mucosa and palate) (26.6% versus 11.5%). In male patients, this difference was statistically significant (p less than 0.05). 4 tumours were synchronous. In those 4 patients, panendoscopy would not have contributed to an earlier diagnosis. Routine panendoscopy in oral cancer therefore seems not valid.
de Vries
N
N
Van der Waal
I
I
Snow
G B
GB
D005260:Female; D006801:Humans; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D012737:Sex Factors; D013997:Time Factors; D014062:Tongue Neoplasms / Q000473:pathology