Monoclonal antibodies and the haemostasis laboratory: current position.
In recent years research laboratories have produced a wide variety of monoclonal antibodies to haemostatic proteins. While these have proven very useful in fundamental research they have not, as yet, been widely used as routine reagents. This article reviews the range of monoclonal antibodies currently available and discusses their potential applications in routine laboratory practice.
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D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D001779:Blood Coagulation Factors / Q000032:analysis; D002846:Chromatography, Affinity; D003429:Cross Reactions; D004591:Electrophoresis, Polyacrylamide Gel; D004797:Enzyme-Linked Immunosorbent Assay; D005342:Fibrinolysis; D005344:Fibrinopeptide A / Q000032:analysis; D005345:Fibrinopeptide B / Q000032:analysis; D005455:Fluorescent Antibody Technique; D006487:Hemostasis; D006651:Histocytochemistry; D006801:Humans; D007120:Immunochemistry; D005779:Immunodiffusion / Q000379:methods; D007124:Immunoenzyme Techniques; D008722:Methods; D011863:Radioimmunoassay; D014842:von Willebrand Diseases / Q000175:diagnosis
D000911:Antibodies, Monoclonal; D001779:Blood Coagulation Factors; D005344:Fibrinopeptide A; D005345:Fibrinopeptide B