[Juvenile spongiform encephalopathy with unusual pathomorphologic findings].
A 27-year-old man presented disturbances of gait and language, quickly followed by intellectual deterioration, tetraplegia, anarthria and myoclonus. Histological examination of a cerebral biopsy showed not only cortical changes consistent with the diagnosis of Creutzfeldt-Jakob disease, but also many amyloid-plaques with variable morphology. The diagnostic interpretation of the case particularly as to concern his relationship to s.c. Gerstmann-Strüssler syndrome is discussed.
Galatioto
S
S
Istituto di Scienze Neurologiche e Neurochirurgiche dell'Università di Messina.
De Luca
M J
MJ
Majorana
A
A
Puglisi
R M
RM
Gugliotta
M A
MA
Distefano
G
G
D000328:Adult; D000367:Age Factors; D007562:Creutzfeldt-Jakob Syndrome / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D012897:Slow Virus Diseases / Q000150:complications / Q000473:pathology*
Encefalopatia spongiforme giovanile con insoliti reperti patomorfologici.