Absence of mutagenic activity of acidity regulators in the Ames Salmonella/microsome test.
The activities of various concentrations of 4 acidity regulators (anhydrous citric acid, phosphoric acid, malic acid and lactic acid) used in food industries in Iraq was assayed using the Salmonella/microsome mutagenicity assay. None of the samples was mutagenic in the absence or in the presence of S9 to any of the tester strains of Salmonella typhimurium.
Al-Ani
F Y
FY
Department of Biology, College of Science, Baghdad University, Iraq.
Al-Lami
S K
SK
D000818:Animals; D001711:Biotransformation; D002951:Citrates / Q000494:pharmacology*; D019343:Citric Acid; D005503:Food Additives / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D007773:Lactates / Q000494:pharmacology*; D019344:Lactic Acid; D008293:Malates / Q000494:pharmacology*; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism; D009152:Mutagenicity Tests; D010756:Phosphoric Acids / Q000494:pharmacology*; D051381:Rats; D012486:Salmonella typhimurium / Q000187:drug effects*
D002951:Citrates; D005503:Food Additives; D007773:Lactates; D008293:Malates; D010756:Phosphoric Acids; D019343:Citric Acid; D019344:Lactic Acid; C030298:malic acid; C030242:phosphoric acid