title: Sulphur compounds used in medicine.
abstract: Native sulphur has had limited success as a medicinal agent. There is, however, hardly a class of drugs which does not contain compounds having sulphur in their structure. Sulphur-containing dyes have given rise to many clinically useful substances, others, such as the -lactam antibiotics, have been developed from naturally occurring molecules and yet others have been designed on the basis of a detailed understanding of physiological mechanisms. Sulphur occurs in drug molecules in all its oxidative states and in all its forms of organic combination. Organo-sulphur compounds, unquestionably form a major therapeutic resource and their potential remains to be further exploited.
authors.affiliation: Glaxo Group Research Ltd., Greenford, Middlesex.
authors.forename: M
authors.initials: M
authors.lastname: Mitchard
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004396:Coloring Agents; D015195:Drug Design; D006801:Humans; D013449:Sulfonamides / Q000627:therapeutic use; D013455:Sulfur / Q000627:therapeutic use*
chemical_list: D000900:Anti-Bacterial Agents; D004396:Coloring Agents; D013449:Sulfonamides; D013455:Sulfur