[Defects in the prostaglandin system. VI. Acquired plasma factor defect].
A 44 year-old male was admitted to hospital in October 1984 presenting with enzymatic and electrocardiographic signs of posterior wall myocardial infarction. At this time 2 separate examinations revealed normal plasma factor activity. At the 1 year follow-up (November 1985) plasma factor activity was still present. However, in February 1987 for the first time, the patient's plasma failed to enhance PGI2 synthesis from vascular tissue in vitro. 3 further follow-up examinations within the next 6 weeks again revealed an acquired absence of plasma factor activity of unknown cause. No deterioration in clinical condition occurred. All relatives tested showed normal plasma factor activity.
Sinzinger
H
H
Atheroskleroseforschungsgruppe (ASF), Wien.
Fitscha
P
P
Rauscha
F
F
Kaliman
J
J
D000328:Adult; D001685:Biological Factors / Q000172:deficiency*; D001798:Blood Proteins / Q000172:deficiency*; D011464:Epoprostenol / Q000096:biosynthesis; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000097:blood*; D010979:Platelet Function Tests
D001685:Biological Factors; D001798:Blood Proteins; C057670:prostacyclin synthesis stimulating plasma factor; D011464:Epoprostenol
Defekte im Prostaglandinsystem. VI. Erworbener Plasmafaktordefekt.