title: Idiopathic hypereosinophilic syndrome.
abstract: Idiopathic hypereosinophilic syndrome is a rare but clearly defined cause of peripheral eosinophilia. The cardiovascular and hematopoietic systems are most severely affected. The clinical manifestations are a result of eosinophilic infiltration into tissues, release of eosinophilic products, and induction of a hypercoagulable state. Treatment is aimed at reducing absolute numbers of eosinophils to prevent tissue damage and halt progression of the disease.
authors.affiliation: Department of Medicine, University of Kansas Medical Center, Kansas City.
authors.forename: M D
authors.initials: MD
authors.lastname: Jameson
authors.forename: S D
authors.initials: SD
authors.lastname: Segraves
mesh_terms: D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D004802:Eosinophilia / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D006331:Heart Diseases / Q000209:etiology; D006801:Humans; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D011379:Prognosis; D013577:Syndrome
chemical_list: D011241:Prednisone