[Enhanced resistance of mice (CBA strain) to infection caused by S. typhimurium depending on the nature of the fat in the diet].
Mice received rations containing a mixture of lard with sunflower oil, butter, cooking fat (hydrogenated), fish fat. Hydrogenated fat and fish fat induced a decrease in the portion of polyunsaturated fatty acid omega 6 in lipids of lymphocytes, Peyer's patches, mesenteric lymph nodes and the spleen. At the same time fish fat induced an increase of the portion of polyunsaturated fatty acid omega 3 in lipids studied. A relationship has been noted between the animal survival after intraperitoneal infection with S. Typhimurium and the fatty acid composition in lymphoid tissues. The highest survival rate has been recorded in the groups of animals that received cooking (hydrogenated) fat and fish fat.
Volgarev
M N
MN
Khaĭrov
Kh S
KhS
Kulakova
S N
SN
Sergeeva
K V
KV
Levachev
M M
MM
D000818:Animals; D004042:Dietary Fats, Unsaturated / Q000008:administration & dosage*; D007113:Immunity, Innate / Q000187:drug effects; D008055:Lipids / Q000032:analysis; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA / Q000276:immunology*; D012481:Salmonella Infections, Animal / Q000178:diet therapy / Q000276:immunology* / Q000378:metabolism / Q000401:mortality; D012486:Salmonella typhimurium
D004042:Dietary Fats, Unsaturated; D008055:Lipids
Povyshenie rezistentnosti mysheĭ (linii CBA) k infektsii, vyzvannoĭ S. typhimurium, v zavisimosti ot kharaktera zhira v ratsione.