[Interferon preparations in the treatment of acute and chronic forms of hepatitis B].
The therapeutic efficacy of human leucocytic alpha-interferon and combiferon produced in the N.F. Gamaleya Institute of Epidemiology and Microbiology, was assessed in 27 patients with different types of hepatitis B and in 30 controls. A marked clinical effect was noted in therapy of acute types of hepatitis B: the improvement of clinical and immunological indices, the reduction of the duration of HBs-antigenemia. The treatment of chronic types was effective in 5 out of 8 patients. A therapeutic scheme for acute and chronic types of hepatitis B was given.
Botsvadze
E Sh
ESh
Katsitadze
T K
TK
Kuznetsov
V P
VP
Kvitashvili
M A
MA
Gogichaĭshvili
Sh Sh
ShSh
D000208:Acute Disease; D000328:Adult; D002675:Child, Preschool; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D004338:Drug Combinations / Q000627:therapeutic use; D005260:Female; D006509:Hepatitis B / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007370:Interferon Type I / Q000008:administration & dosage / Q000627:therapeutic use*; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D008297:Male; D008875:Middle Aged; D011994:Recombinant Proteins
D004338:Drug Combinations; D007370:Interferon Type I; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; C058673:combiferon
Preparaty interferona v lechenii ostrykh i khronicheskikh form gepatita B.