title: Clinically significant Streptococcus anginosus (Streptococcus milleri) infections: a review of 186 cases.
abstract: We describe clinically significant infections due to Streptococcus anginosus in 186 patients; 114 (61.3%) males and 72 (38.7%) females, median age 42 years, range 9 months to 93 years. In 101 (54.3%) cases S anginosus alone caused infection and in 85 (45.7%) cases it was associated with other microorganisms. Abscesses accounted for 110 (59.1%) infections. Sites of infection were: miscellaneous skin and soft tissue, 64 (34.4%), intraabdominal 41 (22%), head and neck 34 (18.3%), pleuropulmonary 22 (11.8%), genitourinary 9 (4.8%), musculoskeletal 6 (3.2%), endocarditis 5 (2.7%) and primary bacteraemia 5 (2.7%). Treatment consisted of antibiotic therapy which was often prolonged, median 30 days, range 2-90 days, and surgery in 159 (85.5%). S anginosus infection was a contributory factor in two of the three deaths which occurred.
authors.affiliation: Middlemore Hospital, Auckland.
authors.forename: K P
authors.initials: KP
authors.lastname: Singh
authors.forename: A
authors.initials: A
authors.lastname: Morris
authors.forename: S D
authors.initials: SD
authors.lastname: Lang
authors.forename: D M
authors.initials: DM
authors.lastname: MacCulloch
authors.forename: D A
authors.initials: DA
authors.lastname: Bremner
mesh_terms: D000038:Abscess / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009520:New Zealand; D012189:Retrospective Studies; D013290:Streptococcal Infections / Q000150:complications / Q000453:epidemiology / Q000382:microbiology*; D013291:Streptococcus / Q000145:classification / Q000302:isolation & purification