title: Effects of Nd:YAG and CO2 lasers on cerebral microvasculature. Study in normal rabbit brain.
abstract: The effect of Nd:YAG and CO2 laser beams on cerebral microvasculature was examined in experimental animals. Soft x-ray microangiography and histological examination of the brain after Nd:YAG laser exposure revealed broad avascular or oligovascular zones in the irradiated and the surrounding edematous tissue, in which the surviving vessels were narrowed and tapered without significant leakage of blood. After CO2 laser exposure, a wedge-shaped tissue defect surrounded by layers of charring, coagulation, and edema was observed. The main finding in the surrounding coagulation and edematous layers was dilatation of the vessels. Hemorrhage was sometimes observed, mainly in the edematous layer. These findings seem to explain the effective hemostatic capability of the Nd:YAG laser and the occasional hemorrhage following CO2 laser exposure, especially at high energy output.
authors.forename: T
authors.initials: T
authors.lastname: Kuroiwa
authors.forename: M
authors.initials: M
authors.lastname: Tsuyumu
authors.forename: H
authors.initials: H
authors.lastname: Takei
authors.forename: Y
authors.initials: Y
authors.lastname: Inaba
mesh_terms: D000818:Animals; D001921:Brain / Q000098:blood supply* / Q000473:pathology / Q000648:ultrastructure; D001929:Brain Edema / Q000209:etiology / Q000473:pathology; D002245:Carbon Dioxide; D002543:Cerebral Hemorrhage / Q000209:etiology / Q000473:pathology; D007834:Lasers / Q000009:adverse effects; D011817:Rabbits
chemical_list: D002245:Carbon Dioxide