[Anticonvulsive properties of enomelanin].
Antiepileptic effects of enomelanin (natural oligomer obtained from pressed grapes) were analysed on the models of focal and clonic-tonic epileptic activity (EA). Electrocorticographic and motor manifestations of EA have been studied. Enomelanin in EA models used was shown to possess marked anticonvulsive properties.
Kryzhanovskiĭ
G N
GN
Bartsevich
L B
LB
Lobasiuk
B A
BA
Zherebin
Iu L
IuL
Osipova
L A
LA
D000818:Animals; D000927:Anticonvulsants / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000139:chemically induced / Q000188:drug therapy; D004827:Epilepsy / Q000139:chemically induced / Q000188:drug therapy; D010406:Penicillins / Q000494:pharmacology; D010433:Pentylenetetrazole / Q000494:pharmacology; D051381:Rats
D000927:Anticonvulsants; D010406:Penicillins; D010433:Pentylenetetrazole
Izuchenie protivosudorozhnykh svoĭstv énomelanina.