title: Diagnostic value of the stereotactic approach to focal lesions in the deep brain of children and adolescents.
abstract: Since it is relatively harmless, stereotactic biopsy has become in recent years a useful method for the diagnostic assessment of lesions deep in the brain, which are not accessible to open surgery. With the aid of stereotaxis, focal lesions only a few millimeters in diameter can be approached in every location in the brain with high precision. Since stereotaxis does not require general anesthesia, or at most requires only a very shallow anesthesia, it can also be applied to young infants or persons of advanced age. Experience with stereotactic biopsy exploration of lesions of various kinds in the deep brain of 74 children and adolescents, out of a sample of 260 patients of all age groups who received stereotactic biopsy, is reported. Our aim is to demonstrate and discuss the advantage of this contemporary method for child neurology and neurosurgery. In many medical centers in the world where stereotactic tumor biopsy has been established, it has become an important criterion for the choice of treatment.
authors.affiliation: Institute of Neuropathology, University of Heidelberg Medical School, Germany (FRG).
authors.forename: H P
authors.initials: HP
authors.lastname: Schmitt
authors.forename: B
authors.initials: B
authors.lastname: Wowra
authors.forename: V
authors.initials: V
authors.lastname: Sturm
mesh_terms: D000293:Adolescent; D001254:Astrocytoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology*; D001707:Biopsy, Needle / Q000379:methods*; D001927:Brain Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology*; D001932:Brain Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D013238:Stereotaxic Techniques; D014055:Tomography, Emission-Computed