title: Hypersensitivity reactions to etoposide. A case report and review of the literature.
abstract: A case of immediate hypersensitivity to the chemotherapeutic agent etoposide is reported. The clinical details of the case and features of previously reported cases are outlined. An attempt to re-treat the patient with etoposide was unsuccessful despite vigorous premedication, in contrast to previous reports. The mechanism of hypersensitivity to this agent is still to be elucidated.
authors.affiliation: Department of Medicine, University of Minnesota Medical School, Minneapolis.
authors.forename: K M
authors.initials: KM
authors.lastname: Ogle
authors.forename: B J
authors.initials: BJ
authors.lastname: Kennedy
mesh_terms: D000328:Adult; D004342:Drug Hypersensitivity; D005047:Etoposide / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000188:drug therapy; D013899:Thoracic Neoplasms / Q000188:drug therapy
chemical_list: D005047:Etoposide