Carbamazepine in the treatment of aggression: a case report and a review of the literature.
Aggressive behaviour is an inescapable clinical problem confronting practitioners of medicine, neurology and psychiatry. Several drugs have been used to treat it, with limited success. Successful use of carbamazepine in the treatment of aggressive behaviour in a patient with limbic dysfunction is reported, and varieties of aggressive behaviour that respond to carbamazepine are examined. The authors suggest that carbamazepine may have a specific anti-aggressive effect perhaps due to an anti-kindling effect, but caution that double-blind studies are needed before firm conclusions are drawn.
Yatham
L N
LN
St. Ita's Hospital, Portrane, Co. Dublin, Republic of Ireland.
McHale
P A
PA
D000293:Adolescent; D000374:Aggression / Q000187:drug effects*; D002220:Carbamazepine / Q000627:therapeutic use*; D004833:Epilepsy, Temporal Lobe / Q000188:drug therapy*; D006801:Humans; D007696:Kindling, Neurologic / Q000187:drug effects; D008032:Limbic System / Q000187:drug effects; D008297:Male
D002220:Carbamazepine