title: [Derivatives of phenoxyacetamide and antimycotic activity].
abstract: Novel N-(3-methyl-4-R-isoxazol-5-yl)-2-R1-4-R2-phenoxyacetamides and N-(3-methyl-4-R-isoxazol-5-yl)-2-(2-R1-4-R2-phenoxyacetamido) benzamides were prepared and tested against Candida albicans and Cryptococcus neoformans. The results of the antimicrobial assay showed that the presence of two amidic groups usually enhances antimycotic activity.
authors.affiliation: Dipartimento di Chimica e Tecnologie Farmaceutiche, Universita di Palermo.
authors.forename: G
authors.initials: G
authors.lastname: Daidone
authors.forename: D
authors.initials: D
authors.lastname: Raffa
authors.forename: M L
authors.initials: ML
authors.lastname: Bajardi
authors.forename: S
authors.initials: S
authors.lastname: Plescia
authors.forename: M
authors.initials: M
authors.lastname: Milici
mesh_terms: D000081:Acetamides / Q000138:chemical synthesis* / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis*; D002176:Candida albicans / Q000187:drug effects; D003455:Cryptococcus neoformans / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D013329:Structure-Activity Relationship
chemical_list: D000081:Acetamides; D000935:Antifungal Agents
vernacular_title: Derivati della fenossiacetammide ad attività antimicotica.