title: [Effect of inhibitors and cations on the proteolytic activity of Bacillus mesentericus].
abstract: The effect of some inhibitors and bivalent metal cations (Mn2+, Ca2+, Fe2+, Zn2+, Mg2+, Co2+ and Cu2+) on the proteolytic activity of two Bacillus mesentericus strains (strain 8 and strain 64 M-variant) was comparatively studied. The both enzymes were shown to be serine proteinases, but the proteinase of strain 64 was also a metal-dependent enzyme. Metal ions exerted no essential effect on the proteinase of strain 8. Ca2+ and Mg2+ ions stimulated the proteinase activity of strain 64 whereas Fe2+ and Zn2+ ions inhibited it in the case of three substrates. Therefore, the two proteinases are different.
authors.forename: A A
authors.initials: AA
authors.lastname: Imshenetskiĭ
authors.forename: N G
authors.initials: NG
authors.lastname: Nesterova
authors.forename: G V
authors.initials: GV
authors.lastname: Cherkesova
authors.forename: Z S
authors.initials: ZS
authors.lastname: Fetisova
mesh_terms: D001230:Aspergillus / Q000187:drug effects / Q000201:enzymology; D001407:Bacillus / Q000187:drug effects* / Q000201:enzymology; D002412:Cations; D005342:Fibrinolysis / Q000187:drug effects; D006801:Humans; D008670:Metals / Q000494:pharmacology*; D010447:Peptide Hydrolases / Q000494:pharmacology; D011480:Protease Inhibitors / Q000494:pharmacology*
chemical_list: D002412:Cations; D008670:Metals; D011480:Protease Inhibitors; D010447:Peptide Hydrolases
vernacular_title: Vliianie ingibitorov i nekotorykh kationov na proteoliticheskuiu aktivnost' Bacillus mesentericus.