title: Penicillium marneffei infection: an underdiagnosed disease?
abstract: Penicillium marneffei is a rare human pathogen that often causes problems in clinical and histological diagnosis. A patient who presented with autoimmune haemolytic anaemia and hepatosplenomegaly, and was subsequently found to be suffering from disseminated Penicillium marneffei infection, is reported. The liver biopsy showed epithelioid cell granulomas only, and tuberculosis was initially considered the most likely diagnosis. The correct diagnosis became evident in a subsequent colonic biopsy, which showed extensive infiltration by penicillium-laden macrophages.
authors.affiliation: Institute of Pathology, Queen Elizabeth Hospital, Hong Kong.
authors.forename: D N
authors.initials: DN
authors.lastname: Tsang
authors.forename: J K
authors.initials: JK
authors.lastname: Chan
authors.forename: Y T
authors.initials: YT
authors.lastname: Lau
authors.forename: W
authors.initials: W
authors.lastname: Lim
authors.forename: C H
authors.initials: CH
authors.lastname: Tse
authors.forename: N K
authors.initials: NK
authors.lastname: Chan
mesh_terms: D001424:Bacterial Infections / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D010407:Penicillium