Urologic pharmacology in the office setting.
The authors discuss two areas of therapeutics employed commonly in office practice, namely, anti-infective therapy and therapy for disorders of micturition. In anti-infective therapy, the pharmacodynamic aspects of drug action, as exemplified by the in-vitro susceptibility of various pathogens to antibiotics, are often known before the drug is administered to the patient. Thus, therapeutic failures generally result from a lack of knowledge of the individual patient's pharmacokinetics. In contrast, drug therapy for disorders of micturition is directed against a variety of often conflicting mechanisms and is seldom based on any pharmacokinetic tenets.
Reed
M D
MD
Case Western Reserve University School of Medicine, Cleveland, Ohio.
Blumer
J L
JL
D000553:Ambulatory Care; D000900:Anti-Bacterial Agents / Q000493:pharmacokinetics / Q000627:therapeutic use; D004352:Drug Resistance, Microbial; D006801:Humans; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000378:metabolism*; D014555:Urination Disorders / Q000188:drug therapy / Q000378:metabolism*
D000900:Anti-Bacterial Agents