title: [Hypostamine (tritoqualine), a synthetic reference antihistaminic].
abstract: The role of histamine in hypersensitivity reactions justifies the use of antagonistic medication. The symptomatic action of the antihistamines has led many workers to forget the role of the drug in reducing histamine (hypohistaminic), in which interest should remain as a curative and mainly preventive medication. The main indications for the action of this drug at the level of physiopathological mechanism involved are: disorders that implicate the production of endogenous histamine, prevention of histamine release, reduction of over-production of histamine by regulation of receptor saturation, symptomatic action without side effects.
authors.affiliation: Pneumologue Allergologue, C.H.U. Tours.
authors.forename: A
authors.initials: A
authors.lastname: Sonneville
mesh_terms: D001681:Biological Assay; D002262:Carboxy-Lyases / Q000037:antagonists & inhibitors*; D006640:Histidine Decarboxylase / Q000037:antagonists & inhibitors*; D049673:History, 20th Century; D006801:Humans; D007546:Isoquinolines / Q000266:history / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D007546:Isoquinolines; D002262:Carboxy-Lyases; D006640:Histidine Decarboxylase; C003722:tritoqualine
vernacular_title: L'hypostamine (tritoqualine), hypohistaminémiant de synthèse de référence.