title: In vitro response of Plasmodium falciparum to chloroquine and mefloquine in southeast Madagascar.
abstract: 46 isolates of Plasmodium falciparum collected in the Tolagnaro (Fort Dauphin) area of Southeast Madagascar were assessed with WHO in vitro micro-technique test kits to determine their susceptibility to chloroquine and mefloquine. The results of the tests indicated low grade resistance to chloroquine and satisfactory response to mefloquine.
authors.forename: M B
authors.initials: MB
authors.lastname: Kightlinger
authors.forename: L K
authors.initials: LK
authors.lastname: Kightlinger
mesh_terms: D000818:Animals; D000962:Antimalarials / Q000494:pharmacology*; D002738:Chloroquine / Q000494:pharmacology*; D004351:Drug Resistance; D066298:In Vitro Techniques; D008270:Madagascar; D015767:Mefloquine; D010963:Plasmodium falciparum / Q000187:drug effects*; D011804:Quinolines / Q000494:pharmacology*
chemical_list: D000962:Antimalarials; D011804:Quinolines; D002738:Chloroquine; D015767:Mefloquine