title: Changes in TRH immunoreactivity in spinal cord after experimental spinal injury.
abstract: Concentrations of immunoreactive TRH (TRH-ir) in rat spinal cord were examined after traumatic injury. TRH-ir was significantly increased at the injury site (thoracic region) and rostral areas (cervical region), and significantly decreased below the injury site. Changes were delayed and time-dependent. Since TRH may serve as an excitatory neurotransmitter within the spinal cord, these changes may contribute to the functional alterations observed after spinal injury.
authors.forename: A I
authors.initials: AI
authors.lastname: Faden
authors.forename: T G
authors.initials: TG
authors.lastname: Hill
authors.forename: M J
authors.initials: MJ
authors.lastname: Kubek
mesh_terms: D000818:Animals; D008297:Male; D011863:Radioimmunoassay; D051381:Rats; D011919:Rats, Inbred Strains; D013116:Spinal Cord / Q000032:analysis*; D013119:Spinal Cord Injuries / Q000378:metabolism*; D013973:Thyrotropin-Releasing Hormone / Q000032:analysis*
chemical_list: D013973:Thyrotropin-Releasing Hormone