title: [Juvenile spongiform encephalopathy with unusual pathomorphologic findings].
abstract: A 27-year-old man presented disturbances of gait and language, quickly followed by intellectual deterioration, tetraplegia, anarthria and myoclonus. Histological examination of a cerebral biopsy showed not only cortical changes consistent with the diagnosis of Creutzfeldt-Jakob disease, but also many amyloid-plaques with variable morphology. The diagnostic interpretation of the case particularly as to concern his relationship to s.c. Gerstmann-Strüssler syndrome is discussed.
authors.affiliation: Istituto di Scienze Neurologiche e Neurochirurgiche dell'Università di Messina.
authors.forename: S
authors.initials: S
authors.lastname: Galatioto
authors.forename: M J
authors.initials: MJ
authors.lastname: De Luca
authors.forename: A
authors.initials: A
authors.lastname: Majorana
authors.forename: R M
authors.initials: RM
authors.lastname: Puglisi
authors.forename: M A
authors.initials: MA
authors.lastname: Gugliotta
authors.forename: G
authors.initials: G
authors.lastname: Distefano
mesh_terms: D000328:Adult; D000367:Age Factors; D007562:Creutzfeldt-Jakob Syndrome / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D012897:Slow Virus Diseases / Q000150:complications / Q000473:pathology*
vernacular_title: Encefalopatia spongiforme giovanile con insoliti reperti patomorfologici.