Fundamentals in the prophylaxis of septic surgical complications.
An operation in which the colonic/rectal wall is opened represents a destruction of a complicated balance between the patient and his intestinal micro-flora, giving way for infective micro-organisms to become established. The surgeon should try to minimize the number of organisms reaching the operation field and reduce their possibilities of establishment. Some strategical and tactical guide-lines for achieving these goals are given.
Midtvedt
T
T
Institute of Medical Microbial Ecology, Karolinska Institute, Stockholm, Sweden.
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D015179:Colorectal Neoplasms / Q000601:surgery*; D006801:Humans; D007422:Intestines / Q000382:microbiology; D011292:Premedication; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000517:prevention & control*
D000900:Anti-Bacterial Agents