Continuous blockade of the lumbar plexus after knee surgery--postoperative analgesia and bupivacaine plasma concentrations. A controlled clinical trial.
In a double blind, randomised, controlled investigation the analgesic effect of a continuous block of the lumbar plexus with bupivacaine compared with sodium chloride was examined in 20 patients with postoperative pain after knee-joint surgery. The infusion was given through a catheter inserted in the neurovascular fascial sheath of the femoral nerve, according to the three-in-one block technique. The patients treated with bupivacaine had significantly lower pain scores and a significantly lower demand for morphine. Side effects related to the catheters or the infusions of bupivacaine were not observed.
Dahl
J B
JB
Department of Anaesthesia, Arhus County Hospital, Denmark.
Christiansen
C L
CL
Daugaard
J J
JJ
Schultz
P
P
Carlsson
P
P
D000293:Adolescent; D000328:Adult; D002045:Bupivacaine / Q000008:administration & dosage / Q000097:blood*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000601:surgery*; D008160:Lumbosacral Plexus; D008297:Male; D009020:Morphine / Q000008:administration & dosage; D009407:Nerve Block; D010149:Postoperative Pain / Q000628:therapy*; D010342:Patient Acceptance of Health Care; D011897:Random Allocation
D009020:Morphine; D002045:Bupivacaine