title: Non-O:1 Vibrio cholerae bacteremia: case report and review.
abstract: A case of non-O:1 Vibrio cholerae bacteremia and prostatic abscess in a patient with idiopathic aplastic anemia was studied, and the data were compared with those from 23 previously reported cases of non-O:1 V. cholerae bacteremia. The case-fatality rate for the 13 cases for which the outcome is known is 61.5%. The majority of known cases have occurred in immunocompromised patients, particularly those with hematologic malignancy or cirrhosis. Host susceptibility is potentially important in this condition. Bacterial products such as a cholera-like toxin and El Tor hemolysin also may play a role in the disease process. The incidence of enteritis due to non-O:1 V. cholerae is unclear because of the methods used for routine stool culture; however, the small number of reported isolates from blood is likely to reflect the infrequency of bacteremia, since Vibrio species are readily identifiable on sheep blood agar. While non-O:1 V. cholerae is sensitive to most antibiotics in vitro, no data are available on antibiotic efficacy.
authors.affiliation: Divisions of Infectious Diseases, University of California, San Francisco 94143.
authors.forename: S
authors.initials: S
authors.lastname: Safrin
authors.forename: J G
authors.initials: JG
authors.lastname: Morris
authors.forename: M
authors.initials: M
authors.lastname: Adams
authors.forename: V
authors.initials: V
authors.lastname: Pons
authors.forename: R
authors.initials: R
authors.lastname: Jacobs
authors.forename: J E
authors.initials: JE
authors.lastname: Conte
mesh_terms: D000038:Abscess / Q000209:etiology; D000741:Anemia, Aplastic / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011469:Prostatic Diseases / Q000209:etiology; D018805:Sepsis / Q000209:etiology*; D014735:Vibrio Infections / Q000209:etiology*; D014734:Vibrio cholerae