Magnesium, Staphylococcus aureus and toxic shock syndrome.
In vitro studies led us to a new, coherent hypothesis for the pathogenesis of toxic shock syndrome (TSS). These studies show a hitherto unsuspected role of Mg in the pathogenesis of a serious microbial disease, and suggest one of several possible approaches to the prevention of the disorder.
Kass
E H
EH
Department of Medicine, Harvard Medical School, Boston, Mass.
D000907:Antibodies, Bacterial / Q000276:immunology; D001427:Bacterial Toxins; D004768:Enterotoxins / Q000096:biosynthesis / Q000276:immunology / Q000633:toxicity; D005260:Female; D006801:Humans; D008274:Magnesium / Q000502:physiology; D008275:Magnesium Deficiency / Q000150:complications*; D012772:Shock, Septic / Q000209:etiology*; D013203:Staphylococcal Infections / Q000150:complications* / Q000276:immunology; D013211:Staphylococcus aureus / Q000378:metabolism; D018089:Superantigens; D013630:Tampons, Surgical / Q000009:adverse effects
D000907:Antibodies, Bacterial; D001427:Bacterial Toxins; D004768:Enterotoxins; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal; D008274:Magnesium