title: [Antibiotic therapy of infected cerebrospinal fluid in hydrocephalus treated by a shunt].
abstract: Nine hydrocephalic shunted children with infected cerebrospinal fluid (CSF) were treated. Ages ranged from 0 to 10 years. Diagnosis was made through clinical symptoms, CSF examination, echographic and computed tomography (CT). The microorganism which was seen more frequently, was S. epidermidis. This germ was more often found in young children. Treatment of these patients consisted of a systematic change of the shunt which was externally diverted, implantation of a CSF Ommaya reservoir in the lateral ventricle, and intraventricular and systemic administration of antibiotic, were made. Using this protocol CSF sterilization was obtained in all cases, after 5 to 12 days of treatment. CSF shunt infected with S. epidermidis can be effectively cleaned with daily intra-shunt vancomycin, and shunt infected with gram-negative are also cleaned with daily intra-shunt gentamycin.
authors.affiliation: Servicio de Neurocirugía, Hospital La Paz, Madrid.
authors.forename: A
authors.initials: A
authors.lastname: Isla Guerrero
authors.forename: P
authors.initials: P
authors.lastname: Peña García
authors.forename: V
authors.initials: V
authors.lastname: Ortega
authors.forename: F
authors.initials: F
authors.lastname: Alvarez Ruiz
authors.forename: M
authors.initials: M
authors.lastname: Moriche Carretero
authors.forename: E
authors.initials: E
authors.lastname: Paredes García
authors.forename: M
authors.initials: M
authors.lastname: García Blázquez
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002557:Cerebrospinal Fluid Shunts / Q000009:adverse effects* / Q000295:instrumentation; D002648:Child; D002675:Child, Preschool; D005839:Gentamicins / Q000008:administration & dosage; D006801:Humans; D006849:Hydrocephalus / Q000134:cerebrospinal fluid* / Q000150:complications / Q000628:therapy; D007223:Infant; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000209:etiology; D014640:Vancomycin / Q000008:administration & dosage
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins; D014640:Vancomycin
vernacular_title: Antibioticoterapia del LCR infectado en hidrocefalias tratadas con shunt.