title: [Immune reactions of the conjunctiva and cornea following severe chemical burns of the outer eye].
abstract: Conjunctival and corneal tissue samples from nine patients with severe changes after acid and alkali burns were examined immunohistochemically. Epithelial HLA Class II antigen expression was present in three of five conjunctival samples, and all of the antigen markers examined in the conjunctival stroma could be stained. HLA Class II expression was demonstrated in four out of five corneal tissue samples. The results show that in Grade III or IV chemical burns, with the diverse changes of the external eye that they produce, immunological and possibly also autoimmune mechanisms can influence the clinical course.
authors.affiliation: Univ.-Augenklinik Tübingen Abteilung I: Allgemeine Augenheilkunde mit Poliklinik.
authors.forename: H J
authors.initials: HJ
authors.lastname: Thiel
authors.forename: U
authors.initials: U
authors.lastname: Richter
authors.forename: M
authors.initials: M
authors.lastname: Zierhut
authors.forename: C
authors.initials: C
authors.lastname: Müller
mesh_terms: D001327:Autoimmune Diseases / Q000276:immunology; D002057:Burns, Chemical / Q000276:immunology*; D003228:Conjunctiva / Q000276:immunology*; D003315:Cornea / Q000276:immunology*; D005126:Eye Burns / Q000139:chemically induced* / Q000276:immunology; D006681:HLA-D Antigens / Q000032:analysis*; D015395:Histocompatibility Antigens Class I / Q000032:analysis; D006801:Humans; D007124:Immunoenzyme Techniques; D011379:Prognosis
chemical_list: D006681:HLA-D Antigens; D015395:Histocompatibility Antigens Class I
vernacular_title: Immunreaktionen der Bindehaut und Hornhaut nach schweren Verätzungen des äusseren Auges.