Acute intermittent porphyria complicated by pregnancy.
The case of a woman with acute intermittent porphyria complicated by two pregnancies is described. Both pregnancies gave an exacerbation of the disease. Premature delivery were necessary for both children due to intrauterine growth retardation. The first child died from respiratory distress syndrome, but the second child was healthy apart from transient abstinence symptoms due to pethidine given to the mother during pregnancy. The effect of pregnancy on acute intermittent porphyria is discussed.
Olund
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Department of Obstetrics and Gynaecology, Huddinge University Hospital, Karolinska Institute, Sweden.
D000006:Abdomen, Acute / Q000209:etiology*; D000328:Adult; D002585:Cesarean Section; D005260:Female; D005317:Fetal Growth Retardation / Q000175:diagnosis; D006801:Humans; D007231:Infant, Newborn; D011164:Porphyrias / Q000175:diagnosis*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis*; D014463:Ultrasonography