title: Group G streptococcal neonatal septicaemia: two case reports and a brief review of literature.
abstract: We present 2 cases of early onset group G streptococcal septicaemia in full term neonates, together with a review of 15 previously reported cases, including 3 late onset cases. Most likely the neonates were infected during passage through the birth canal or had been exposed in utero. In one neonate, meconium aspiration occurred, while in the other prolonged rupture of maternal membranes was a risk factor. Both responded well to treatment with benzylpenicillin and gentamicin. Among the 12 previously reported early onset cases, 5 (43%) had a fulminant course with complications such as progressive respiratory distress, shock, and disseminated intravascular coagulation.
authors.affiliation: Streptococcus Department, Statens Seruminstitut, Copenhagen, Denmark.
authors.forename: H
authors.initials: H
authors.lastname: Carstensen
authors.forename: C
authors.initials: C
authors.lastname: Pers
authors.forename: O
authors.initials: O
authors.lastname: Pryds
mesh_terms: D000328:Adult; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010400:Penicillin G / Q000627:therapeutic use; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D012307:Risk Factors; D018805:Sepsis / Q000188:drug therapy / Q000382:microbiology*; D013290:Streptococcal Infections / Q000188:drug therapy / Q000382:microbiology* / Q000635:transmission; D013291:Streptococcus / Q000187:drug effects / Q000302:isolation & purification*
chemical_list: D005839:Gentamicins; D010400:Penicillin G