title: Complex typing of methicillin-resistant Staphylococcus aureus (MRSA).
abstract: To discriminate between methicillin-resistant Staphylococcus aureus from 5 nosocomial outbreaks and from sporadic nosocomial infections, the efficacy of a complex typing scheme by phage typing, biochemical typing, resistance phenotype, plasmid profiles, plasmid patterns and attribution of resistance determinants to the chromosome was studied. In addition to the International Basic Set and experimental phages 88-93, 10 experimental phages from the Public Health Laboratory Service, Colindale, London, were used for phage-typing. The 10 experimental phages from PHLS in particular, in combination with plasmid profiles and plasmid patterns, were of special discriminative value.
authors.affiliation: Institut für Experimentelle Epidemiologie, DDR, Wernigerode.
authors.forename: W
authors.initials: W
authors.lastname: Witte
authors.forename: R R
authors.initials: RR
authors.lastname: Marples
authors.forename: J F
authors.initials: JF
authors.lastname: Richardson
mesh_terms: D015373:Bacterial Typing Techniques; D001434:Bacteriophage Typing; D003428:Cross Infection / Q000382:microbiology*; D004269:DNA, Bacterial / Q000032:analysis; D004352:Drug Resistance, Microbial; D006801:Humans; D008712:Methicillin / Q000494:pharmacology; D010403:Penicillin Resistance; D010957:Plasmids; D013203:Staphylococcal Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000145:classification* / Q000187:drug effects / Q000235:genetics
chemical_list: D004269:DNA, Bacterial; D008712:Methicillin