title: [Detection of liver metastases in gynecologic neoplasms by sonography, scintigraphy, computerized tomography and liver enzymes].
abstract: In a retrospective study the diagnostic validity of sonography (US), computer-tomography (CT), scintigraphy (SC) and serum alkaline phosphatase (AP) in the detection of liver metastases was evaluated in 929 patients with malignant tumors: ovary (n = 367), mamma (n = 189), endometrium (n = 181), cervix (n = 162), fallopian tube (n = 10), vulva (n = 20). Definitive diagnosis was confirmed by autopsy (n = 51), surgical intervention (n = 297) or follow-up (n = 581). Specificity, sensitivity and overall accuracy of the different methods in the indication of liver metastasis were as follows: CT (n = 58) 81%, 98%, 93%, US (n = 929) 70%, 94%, 90%, SC (n = 512) 66%, 85%, 81%, AP (n = 325) 68%, 93%, 87%. In the last examination period, US and CT reached comparable results. In view of efficiency, AP and US would appear suitable for routine control in gynecological malignancies.
authors.affiliation: Universitäts-Frauenklinik, Freiburg.
authors.forename: H
authors.initials: H
authors.lastname: Schillinger
authors.forename: R
authors.initials: R
authors.lastname: Traeder
authors.forename: W
authors.initials: W
authors.lastname: Klosa
authors.forename: J
authors.initials: J
authors.lastname: Pohl
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D003952:Diagnostic Imaging; D005260:Female; D005833:Genital Neoplasms, Female / Q000175:diagnosis*; D006801:Humans; D008111:Liver Function Tests; D008113:Liver Neoplasms / Q000175:diagnosis / Q000556:secondary*; D013671:Technetium Tc 99m Sulfur Colloid; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D013671:Technetium Tc 99m Sulfur Colloid; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase
vernacular_title: Nachweis von Lebermetastasen gynäkologischer Malignome durch Sonographie, Szintigraphie, Computertomographie und Leberenzyme.