title: Dynamic bone scintigraphy in osteochondritis dissecans.
abstract: We report a retrospective study of eighteen patients with pain in the knee or ankle, eleven of whom had osteochondritis dissecans. In these patients the bone-flow time-activity curves were observed after an intravenous injection of a bolus of 99mTc MDP. The curves varied according to the severity of the clinical signs and symptoms. The diagnosis rate was 29% with static scintigraphy and this improved to 57% when dynamic flow studies were used. A positive pattern in the dynamic study together with radiographs and static scintigraphs raised the diagnosis rate to 100%; the sensitivity was 90%. These preliminary results show that dynamic bone scintigraphy holds promise as a technique for identification and management of this condition.
authors.affiliation: Department of Bio Med, Radiation Biology, Chemistry, Brown University, Providence, RI 02194.
authors.forename: R W
authors.initials: RW
authors.lastname: McCullough
authors.forename: E J
authors.initials: EJ
authors.lastname: Gandsman
authors.forename: H E
authors.initials: HE
authors.lastname: Litchman
authors.forename: S L
authors.initials: SL
authors.lastname: Schatz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007717:Knee / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D010007:Osteochondritis / Q000000981:diagnostic imaging*; D010008:Osteochondritis Dissecans / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011865:Radioisotope Dilution Technique; D011877:Radionuclide Imaging; D012039:Regional Blood Flow; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013669:Technetium Tc 99m Medronate
chemical_list: D013669:Technetium Tc 99m Medronate