Self-digestion of erythrocyte membranes of various mammalian species.
1. The rate of self-digestion of main membrane proteins, spectrin and band 3 protein, was studied for erythrocyte membranes of eight mammalian species: man, cow, pig, cat, rabbit, hamster, mouse and rat. 2. Spectrin and band 3 protein were most rapidly degraded in human and pig ghosts. The rates of proteolysis for other species were similar. 3. The rates of self-digestion were correlated neither with lifetime of red cells nor lifespan of animals of various species.
Gaczyńska
M
M
Laboratory of Biophysics of Development and Aging, University of Lódź, Poland.
Bartosz
G
G
Rosin
J
J
Soszyński
M
M
D000818:Animals; D001457:Anion Exchange Protein 1, Erythrocyte / Q000378:metabolism; D002415:Cats; D002417:Cattle; D006224:Cricetinae; D004063:Digestion; D004910:Erythrocyte Membrane / Q000378:metabolism*; D006168:Guinea Pigs; D006801:Humans; D066298:In Vitro Techniques; D008322:Mammals; D051379:Mice; D010447:Peptide Hydrolases / Q000097:blood; D051381:Rats; D013045:Species Specificity; D013049:Spectrin / Q000378:metabolism; D013552:Swine
D001457:Anion Exchange Protein 1, Erythrocyte; D013049:Spectrin; D010447:Peptide Hydrolases