Quinine overdose: review of toxicity and treatment.
Quinine sulfate is a commonly prescribed remedy for idiopathic nocturnal leg cramps and is now available "over the counter." A 24-year-old man ingested 8 g (a commonly dispensed quantity) of quinine sulfate in a suicide attempt. Despite hemoperfusion begun 10 h after ingestion, the patient died. This report reviews the toxic manifestations of quinine and the currently available modes of treatment.
Goldenberg
A M
AM
Department of Medicine, Boston City Hospital, Massachusetts.
Wexler
L F
LF
D000328:Adult; D004305:Dose-Response Relationship, Drug; D006323:Heart Arrest / Q000139:chemically induced*; D006801:Humans; D006852:Hydrochlorothiazide / Q000506:poisoning; D008297:Male; D011803:Quinine / Q000506:poisoning*; D013405:Suicide
D006852:Hydrochlorothiazide; D011803:Quinine