title: In vitro influence of charcoal on ciprofloxacin activity.
abstract: The effect of charcoal-containing media on ciprofloxacin (BAY o 9867) has been evaluated. The minimal inhibitory concentrations of ciprofloxacin are increased by the presence of charcoal, thus a correction factor has to be calculated to know the real efficacy of the drug, especially in life-threatening infections such as pneumonia due to Legionella spp.
authors.affiliation: Division of Infectious Diseases, General Hospital, Varese, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Torre
authors.forename: C
authors.initials: C
authors.lastname: Sampietro
authors.forename: C
authors.initials: C
authors.lastname: Quadrelli
authors.forename: W
authors.initials: W
authors.lastname: Bianchi
authors.forename: F
authors.initials: F
authors.lastname: Maggiolo
authors.forename: H
authors.initials: H
authors.lastname: Ohnmeiss
mesh_terms: D002606:Charcoal / Q000494:pharmacology*; D002939:Ciprofloxacin / Q000494:pharmacology*; D004347:Drug Interactions; D004926:Escherichia coli / Q000187:drug effects*; D008826:Microbial Sensitivity Tests
chemical_list: D002606:Charcoal; D002939:Ciprofloxacin