title: [Immunopathogeny of pemphigus].
abstract: This article reviews recent concepts of pathogenetic mechanisms in pemphigus. We describe the pathogenic effect of the autoantibodies, the animal model for the disease and the ultrastructural alterations which follow the antibody-antigen interaction. The role of complement and protease systems in development of tissue injury are also discussed.
authors.affiliation: Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
authors.forename: L
authors.initials: L
authors.lastname: Squiquera
authors.forename: G J
authors.initials: GJ
authors.lastname: Anhalt
authors.forename: L A
authors.initials: LA
authors.lastname: Diaz
authors.forename: S A
authors.initials: SA
authors.lastname: Sampaio
authors.forename: E A
authors.initials: EA
authors.lastname: Rivitti
authors.forename: C R
authors.initials: CR
authors.lastname: Martins
authors.forename: P R
authors.initials: PR
authors.lastname: Cunha
authors.forename: C
authors.initials: C
authors.lastname: Lombardi
authors.forename: F A
authors.initials: FA
authors.lastname: Almeida
authors.forename: A
authors.initials: A
authors.lastname: Martins Castro
mesh_terms: D000818:Animals; D001323:Autoantibodies / Q000276:immunology*; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C; D010392:Pemphigus / Q000209:etiology* / Q000276:immunology
chemical_list: D001323:Autoantibodies
vernacular_title: La inmunopatogenia de los pénfigos.