title: Evaluation of a computerised test for the assessment of peripheral vascular disease.
abstract: This paper reports a study carried out in 200 patients to assess the effectiveness of a clinical vascular laboratory in the routine assessment of peripheral vascular disease (PVD) of the lower limb. Laboratory assessments involved a computer based hierarchical testing system incorporating pedal pressure indices, maximum walking distances and principal component analysis of the common femoral artery blood velocity waveform. The study fell into two parts. In the first, the laboratory assessments of 100 patients referred six years ago were compared retrospectively with their eventual clinical outcome. In this comparison, the laboratory provided a "diagnosis" which was 79% correct. In the second, a double blind prospective study was carried out in 100 patients to compare the vascular laboratory "diagnosis" with the diagnosis and prognosis of a skilled clinician, the outcome being compared one year after the initial assessment. In this study the laboratory proved to be correct in 78% of cases, the clinician in 70%. With a slightly modified computer protocol for the non vascular diagnosis, the computer would have been correct in 85% of cases. This test provides a quantitative and objective assessment of PVD which can assist in the patient's clinical diagnosis and management.
authors.affiliation: Department of Medical Engineering and Physics, King's College School of Medicine & Dentistry, London, U.K.
authors.forename: D E
authors.initials: DE
authors.lastname: Goss
authors.forename: J
authors.initials: J
authors.lastname: Simpson
authors.forename: V C
authors.initials: VC
authors.lastname: Roberts
authors.forename: L T
authors.initials: LT
authors.lastname: Cotton
mesh_terms: D003925:Diabetic Angiopathies / Q000175:diagnosis; D003936:Diagnosis, Computer-Assisted; D003955:Diagnostic Tests, Routine; D005080:Exercise Test; D006801:Humans; D007383:Intermittent Claudication / Q000175:diagnosis; D007866:Leg / Q000098:blood supply*; D011446:Prospective Studies; D012189:Retrospective Studies; D014652:Vascular Diseases / Q000175:diagnosis* / Q000628:therapy