Apolipoprotein C-II deficiencies: in vivo models for assessing the significance of defective lipolysis on lipoprotein metabolism.
There are now several types of apo C-II deficiency. The accumulating evidence suggests that more variants will be discovered which may be inactive or partially active. It seems important to establish accurate assays for assessing optimal properties of lipoproteins for lipolysis in order to continue to diagnose these defects and to study whether rates of lipolysis may influence the accumulation of cholesteryl esters in triacylglycerol-rich lipoproteins.
Breckenridge
W C
WC
Department of Biochemistry, Dalhousie University, Halifax, Nova Scotia.
D053304:Apolipoprotein C-II; D001056:Apolipoproteins C / Q000172:deficiency*; D006801:Humans; D008066:Lipolysis; D008074:Lipoproteins / Q000378:metabolism*; D014280:Triglycerides / Q000378:metabolism
D053304:Apolipoprotein C-II; D001056:Apolipoproteins C; D008074:Lipoproteins; D014280:Triglycerides