The "lung shift" in treated schistosomiasis. Bronchoalveolar lavage evidence of eosinophilic pneumonia.
There is conflicting and incomplete information in the literature on the pulmonary reaction which can occur following treatment of schistosomiasis. We examined the pulmonary function, bronchoalveolar lavage profile, and lung histopathology of a patient with pneumonia and peripheral eosinophilia following oxaminquine chemotherapy for intestinal Schistosoma mansoni infection. Spirometry revealed restrictive rather than obstructive impairment, and lavage showed eosinophil prominence which was also seen in the interstitial and alveolar-filling process in transbronchial biopsies.
Davidson
B L
BL
el-Kassimi
F
F
Uz-Zaman
A
A
Pillai
D K
DK
D000328:Adult; D006801:Humans; D008297:Male; D010073:Oxamniquine / Q000627:therapeutic use; D011650:Pulmonary Alveoli / Q000473:pathology*; D011657:Pulmonary Eosinophilia / Q000209:etiology / Q000473:pathology*; D012555:Schistosomiasis mansoni / Q000150:complications / Q000188:drug therapy*; D007507:Therapeutic Irrigation
D010073:Oxamniquine