title: Management of ruptured intracranial aneurysm: a review.
abstract: The discouraging history associated with management of aneurysmal subarachnoid haemorrhage (SAH) is reviewed along with improvements in outlook attributable to progress made within the past decade. Among the new developments is the introduction of microsurgical techniques that allow elective surgery in the acute stage thereby preventing repeat haemorrhages. Early operation also offers the possibility of a more aggressive pharmacological anti-ischaemic treatment. Notwithstanding the improved results of acute elective surgery and the fact that delayed ischaemic deterioration (symptomatic cerebral vasospasm) now may be almost eliminated, the overall outcome remains gloomy. Despite recent advances not more than one out of three individuals, who are struck by the rupture of an intracranial aneurysm, may be expected to make a good neurological and functional recovery. Hope for further improvements may depend on the development of techniques that can identify intracranial aneurysms before they rupture and increased knowledge of the aetiology of such arterial wall lesions.
authors.affiliation: Department of Neurosurgery, University Hospital, Lund, Sweden.
authors.forename: B
authors.initials: B
authors.lastname: Ljunggren
authors.forename: L
authors.initials: L
authors.lastname: Brandt
authors.forename: H
authors.initials: H
authors.lastname: Säveland
authors.forename: B
authors.initials: B
authors.lastname: Sonesson
authors.forename: B
authors.initials: B
authors.lastname: Romner
authors.forename: S
authors.initials: S
authors.lastname: Zygmunt
authors.forename: K E
authors.initials: KE
authors.lastname: Andersson
authors.forename: P
authors.initials: P
authors.lastname: Mellergård
authors.forename: T
authors.initials: T
authors.lastname: Ryman
mesh_terms: D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D002532:Intracranial Aneurysm / Q000266:history / Q000401:mortality / Q000601:surgery*; D012422:Rupture, Spontaneous; D013345:Subarachnoid Hemorrhage / Q000266:history / Q000401:mortality / Q000601:surgery*; D013548:Sweden