title: Cholescintigraphy in the critically ill.
abstract: Critical review of cholescintigraphy in critically ill patients suggests the examination will not conclusively prove or disprove the diagnosis of acute cholecystitis. Of 17 scans performed in critically ill patients with clinical evidence of acute cholecystitis, 7 were true-negative, 1 was false-negative, 6 were false-positive, and 3 were nondiagnostic. Cholestasis and hepatocyte dysfunction, common in the critically ill, result in abnormal clearance of hepatobiliary radionuclide imaging agents, decreasing the usefulness of cholescintigraphy in this patient population. Diagnosing acute cholecystitis in a critically ill patient remains difficult.
authors.affiliation: Department of Surgery, Ohio State University College of Medicine, Columbus.
authors.forename: W L
authors.initials: WL
authors.lastname: Garner
authors.forename: M V
authors.initials: MV
authors.lastname: Marx
authors.forename: P J
authors.initials: PJ
authors.lastname: Fabri
mesh_terms: D000208:Acute Disease; D002764:Cholecystitis / Q000000981:diagnostic imaging; D003422:Critical Care; D005704:Gallbladder / Q000000981:diagnostic imaging*; D006801:Humans; D007098:Imino Acids; D009942:Organometallic Compounds; D011183:Postoperative Complications / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D019785:Technetium Tc 99m Disofenin
chemical_list: D007098:Imino Acids; D009942:Organometallic Compounds; D019785:Technetium Tc 99m Disofenin