title: Comparison of MYCOPLASMELISA with complement fixation test for measurement of antibodies to Mycoplasma pneumoniae.
abstract: The MYCOPLASMELISA test kit was compared with the complement fixation test for detection of Mycoplasma pneumoniae antibody in single sera and evaluation of acute- and convalescent-phase serum pairs for significant rises in antibody titers. Agreement between the two assays was 96.6% (85 of 88) for antibody detection and 93.9% (92 of 98) for evaluation of paired sera. Sensitivity and specificity of MYCOPLASMELISA, relative to complement fixation, for the serodiagnosis of recent M. pneumoniae infection was 92.2% (59 of 64) and 95% (19 of 20), respectively.
authors.forename: G S
authors.initials: GS
authors.lastname: Fischer
authors.forename: W I
authors.initials: WI
authors.lastname: Sweimler
authors.forename: B
authors.initials: B
authors.lastname: Kleger
mesh_terms: D000907:Antibodies, Bacterial / Q000032:analysis*; D003168:Complement Fixation Tests; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D009177:Mycoplasma pneumoniae / Q000276:immunology* / Q000302:isolation & purification; D011019:Pneumonia, Mycoplasma / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology; D011933:Reagent Kits, Diagnostic
chemical_list: D000907:Antibodies, Bacterial; D011933:Reagent Kits, Diagnostic