title: Susceptibility to beta-lactam antibiotics and gentamicin of gram-negative bacilli isolated from hospitalized patients: a Swedish multicenter study.
abstract: A total of 952 blood and 1543 urine isolates of gram-negative bacilli from hospitalized patients in 1986-1987 were consecutively collected by 10 Swedish laboratories and tested for susceptibility to 8 beta-lactam antibiotics and to gentamicin. The isolates were mostly Escherichia coli (58% and 44%, respectively) and Klebsiella sp. (17% and 18%). Resistance to ampicillin in blood and urine isolates was found in 35% and 45%, respectively, to piperacillin in 5% and 6%, to cephalothin in 26% and 34%, to cefuroxime in 12% and 22%, to cefotaxime in 3% and 5%, to ceftazidime in 1% and 1%, to imipenem in 0.5% and 0.1%, to aztreonam in 3% and 2%, and to gentamicin in 0.8% and 0%. Resistance of clinically important gram-negative bacilli to new beta-lactam antibiotics and to gentamicin is infrequent in Sweden.
authors.affiliation: Department of Clinical Microbiology, Karolinska Hospital, Stockholm, Sweden.
authors.forename: K
authors.initials: K
authors.lastname: Dornbusch
authors.forename: S
authors.initials: S
authors.lastname: Bengtsson
authors.forename: J E
authors.initials: JE
authors.lastname: Brorson
authors.forename: H
authors.initials: H
authors.lastname: Fritz
authors.forename: C
authors.initials: C
authors.lastname: Henning
authors.forename: G
authors.initials: G
authors.lastname: Kronvall
authors.forename: P
authors.initials: P
authors.lastname: Larsson
authors.forename: A S
authors.initials: AS
authors.lastname: Malmborg
authors.forename: M
authors.initials: M
authors.lastname: Thore
authors.forename: A
authors.initials: A
authors.lastname: Tärnvik
mesh_terms: D000667:Ampicillin / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001437:Bacteriuria / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D005839:Gentamicins / Q000494:pharmacology*; D006090:Gram-Negative Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D015337:Multicenter Studies as Topic; D018805:Sepsis / Q000382:microbiology*; D013548:Sweden
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins; D000667:Ampicillin