title: [Hepatic manifestations in Still's disease].
abstract: In children, as in adults, Still's disease usually presents with a hectic fever, a characteristic rash and arthralgia or arthritis. Visceral involvement is however classical; the hepatic manifestations were studied with respect to two cases. Biochemical changes are common, often mild: the commonest abnormality is cytolysis. Jaundice is less frequent and hepatic involvement may in exceptional cases be life threatening, usually in cases of serious polyvisceral disease often with disseminated intravascular coagulation. These manifestations may be spontaneous or secondary to salicylate therapy; the anatomical changes are the same; the salicylate would therefore seem rather to unmask and aggravate an underlying hepatic abnormality.
authors.affiliation: Clinique Médicale, Hôpital d'Instruction des Armées du Valde-Grâce, Paris.
authors.forename: J P
authors.initials: JP
authors.lastname: Algayres
authors.forename: J P
authors.initials: JP
authors.lastname: Daly
authors.forename: B
authors.initials: B
authors.lastname: Oddes
authors.forename: J
authors.initials: J
authors.lastname: Valmary
authors.forename: X
authors.initials: X
authors.lastname: Halna du Fretay
authors.forename: C
authors.initials: C
authors.lastname: Maurel
authors.forename: A
authors.initials: A
authors.lastname: Thomas
authors.forename: M
authors.initials: M
authors.lastname: Chabierski
authors.forename: P
authors.initials: P
authors.lastname: Larroque
authors.forename: C
authors.initials: C
authors.lastname: Laverdant
mesh_terms: D000293:Adolescent; D000328:Adult; D001171:Arthritis, Juvenile / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000209:etiology*; D008297:Male
vernacular_title: Manifestations hépatiques au cours de la maladie de Still.