title: Gene map of the cow: conservation of linkage with mouse and man.
abstract: Cattle-hamster hybrid somatic cells segregating cattle chromosomes have been analyzed by cellulose-acetate electrophoresis for 28 enzyme gene products including the previously unassigned loci for GAPD, ITPA, ADA, ACO1, GDH, GUK, CAT, and GLO1. These 28 loci are organized into 21 independent syntenic groups bringing the composite bovine gene map to 35 loci on 24 syntenic groups. Thirty-two homologous genes now have been mapped in humans, mice, and cattle. Conservation of cattle and human linkage groups is evidenced by only three linkage discordancies among these 32 loci as contrasted to nine discordancies among the same loci in the human and mouse maps.
authors.forename: J E
authors.initials: JE
authors.lastname: Womack
authors.forename: Y D
authors.initials: YD
authors.lastname: Moll
mesh_terms: D000818:Animals; D005075:Biological Evolution; D002417:Cattle / Q000235:genetics*; D002874:Chromosome Mapping; D006224:Cricetinae; D003412:Cricetulus; D004798:Enzymes / Q000235:genetics; D005796:Genes; D008040:Genetic Linkage; D000882:Haplorhini / Q000235:genetics*; D006801:Humans; D006822:Hybrid Cells / Q000166:cytology; D007041:Hypoxanthine Phosphoribosyltransferase / Q000172:deficiency; D051379:Mice / Q000235:genetics*; D013045:Species Specificity
chemical_list: D004798:Enzymes; D007041:Hypoxanthine Phosphoribosyltransferase