Acute dystonic reaction due to diazepam.
Two cases of acute dystonic reactions associated with diazepam ingestion are reported. This report is a brief review of drug-induced extra-pyramidal syndromes, and a mechanism for diazepam-induced dystonic reactions is proposed. Intravenous diphenhydramine was successful in treating both patients.
Hooker
E A
EA
Department of Emergency Medicine, University of Louisville, KY 40292.
Danzl
D F
DF
D000208:Acute Disease; D000328:Adult; D003975:Diazepam / Q000009:adverse effects*; D004155:Diphenhydramine / Q000627:therapeutic use; D004421:Dystonia / Q000139:chemically induced* / Q000188:drug therapy; D005260:Female; D006801:Humans
D004155:Diphenhydramine; D003975:Diazepam