Hemopoietins: roles in inflammation, allergy and neoplasia.
Cytokines link keratinocytes with lymphocytes and the specialized phagocytic and granulocytic cells of the hemopoietic system and are critical elements in the response of the skin to invasion or injury. The cytokine network is complex and includes potential autoregulatory circuits. A better understanding of these networks and of the function and structure of cytokines may lead to a more rational approach to the design of drugs and to new treatments.
Schrader
J W
JW
Biomedical Research Centre University of British Columbia, Vancouver, Canada.
D000818:Animals; D001685:Biological Factors / Q000096:biosynthesis / Q000502:physiology; D001696:Biomechanical Phenomena; D055598:Chemical Phenomena; D002621:Chemistry; D016207:Cytokines; D006133:Growth Substances / Q000502:physiology*; D006410:Hematopoiesis; D016298:Hematopoietic Cell Growth Factors; D006801:Humans; D006967:Hypersensitivity / Q000503:physiopathology*; D007249:Inflammation / Q000503:physiopathology*; D009369:Neoplasms / Q000503:physiopathology*; D013312:Stress, Physiological / Q000378:metabolism; D009626:Terminology as Topic
D001685:Biological Factors; D016207:Cytokines; D006133:Growth Substances; D016298:Hematopoietic Cell Growth Factors