Degradation of bovine achilles tendon collagen by Candida albicans proteinase.
Candida albicans, when cultivated in a medium containing insoluble bovine achilles tendon as a nitrogen source, was able to produce a collagen degrading proteinase. The degradation of achilles tendon collagen by the proteinase was verified by morphological change and the release of hydroxyproline. The proteinase activity was inhibited by pepstatin.
Kaminishi
H
H
Department of Oral Microbiology, Fukuoka Dental College, Japan.
Hagihara
Y
Y
Tanaka
M
M
Cho
T
T
D000125:Achilles Tendon; D000818:Animals; D002176:Candida albicans / Q000201:enzymology*; D002417:Cattle; D003094:Collagen / Q000378:metabolism* / Q000648:ultrastructure; D010450:Endopeptidases / Q000378:metabolism*; D006868:Hydrolysis; D006909:Hydroxyproline / Q000378:metabolism; D008854:Microscopy, Electron
D003094:Collagen; D010450:Endopeptidases; D006909:Hydroxyproline