Changes in androgen binding protein (ABP) production following continuous low dose gamma irradiation (IR) of adult rat.
Continuous low dose gamma irradiation induces a progressive degeneration of germ cells with a concomittant increase in blood FSH; however, the Sertoli cell function is not too much altered since serum ABP level is normal and it is likely that the decrease of epididymal ABP content is the consequence of a reduction in seminiferous tubule fluid excretion. Obviously, spermatids seems to be involved in the regulation of Sertoli cell ABP synthesis.
Kamtchouing
P
P
Department of Biochemistry, UA CNRS 609, CHU 14033 Caen, France.
Pinon-Lataillade
G
G
Papadopoulos
V
V
Drosdowsky
M A
MA
Hochereau de Reviers
M T
MT
Carreau
S
S
D000727:Androgen-Binding Protein / Q000096:biosynthesis*; D000818:Animals; D005720:Gamma Rays; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D014916:Whole-Body Irradiation
D000727:Androgen-Binding Protein