The molecular genetics of Candida albicans.
Candida albicans, the major fungal pathogen of humans, is a diploid with no known sexual cycle. Recent genetic studies in C. albicans include the physical characterization of the genome, the development of systems for parasexual genetics, the cloning of Candida genes, and the development of methods for integrative and ARS-mediated transformation as well as gene disruption.
Kurtz
M B
MB
Squibb Institute for Medical Research, Department of Microbial Biochemistry and Genetics, Princeton, New Jersey 08540.
Kirsch
D R
DR
Kelly
R
R
D002176:Candida albicans / Q000235:genetics*; D003001:Cloning, Molecular; D015966:Gene Expression Regulation, Fungal; D005800:Genes, Fungal; D005821:Genetic Techniques; D010957:Plasmids; D012093:Replicon; D012441:Saccharomyces cerevisiae / Q000235:genetics; D014170:Transformation, Genetic