[Molecular-genetic mechanisms of antigenic variability of pathogenic bacteria].
The literature on the molecular genetic mechanisms for antigenic variability of pathogenic bacteria is reviewed. Ability to antigenic variability in any case discussed is considered to be a pathogenicity factor permitting efficient struggle against the immune system of the host-organism. The molecular basis for such variability is instability of the genome structure, coding for highly immunogenic bacterial proteins.
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D000940:Antigenic Variation; D000942:Antigens, Bacterial / Q000235:genetics*; D001419:Bacteria / Q000235:genetics / Q000276:immunology* / Q000472:pathogenicity
D000942:Antigens, Bacterial
Molekuliarno-geneticheskie mekhanizmy antigennoĭ izmenchivosti patogennykh bakteriĭ.