Pentoxifyllin treatment of oligoasthenospermic men.
A randomised group of 90 men with idiopathic oligoasthenozoospermia was subjected to control study with pentoxifyllin. Pentoxifyllin was given to 51 men 1200 mg daily for 3 months. The other group of 39 infertile men was followed during the same period of time. Significant improvement was observed, in treated group, in percentage of motile sperms and normal shaped sperms after 3 months treatment. This study emphasizes that pentoxifyllin is a relatively good drug for restoring sperm motility and morphology in oligoasthenozoospermic men.
Micic
S
S
Urologic Clinic, Medical Faculty, Belgrade.
Hadzi-Djokic
J
J
Dotlic
R
R
Tulic
C
C
D000328:Adult; D002986:Clinical Trials as Topic; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy*; D008297:Male; D009845:Oligospermia / Q000188:drug therapy*; D010431:Pentoxifylline / Q000008:administration & dosage*; D011897:Random Allocation; D013076:Sperm Count / Q000187:drug effects; D013081:Sperm Motility / Q000187:drug effects; D013805:Theobromine / Q000031:analogs & derivatives*
D013805:Theobromine; D010431:Pentoxifylline