[Hypocomplementary membrano-proliferative glomerulonephritis in a Malagasy patient with schistosomiasis mansoni (detection of bilharzial antigen on glomerular basement membrane using monoclonal antibodies)].
Schistosomiasis due to Schistosoma mansoni affects more than 40 millions people all over the world. Renal involvement is observed mainly in endemic areas. We report a case of hypocomplementemic membrano-proliferative glomerulonephritis in a malagasy man who suffered also from hepatosplenic bilharziosis. The relation between Schistosoma mansoni and the nephropathy was proved by indirect immunofluorescence test using a monoclonal antibody directed against the caecum of adult Schistosoma mansoni.
Rajaonarivelo
P
P
Rajaona
H R
HR
Alix
J L
JL
Couderc
P
P
Daveau
C
C
Santoro
F
F
Nogueira-Quetroz
J A
JA
Lovens
M
M
Capron
A
A
Cordonnier
D
D
D000328:Adult; D000911:Antibodies, Monoclonal / Q000276:immunology; D000947:Antigens, Helminth / Q000032:analysis*; D001485:Basement Membrane / Q000276:immunology; D005455:Fluorescent Antibody Technique; D005921:Glomerulonephritis / Q000209:etiology* / Q000276:immunology; D006801:Humans; D008297:Male; D012550:Schistosoma mansoni / Q000276:immunology*; D012555:Schistosomiasis mansoni / Q000150:complications* / Q000276:immunology
D000911:Antibodies, Monoclonal; D000947:Antigens, Helminth
Glomérulonéphrite membranoproliférative hypocomplémentaire chez un Malgache atteint de bilharziose à Schistosoma mansoni (détection d'antigène bilharzien sur les membranes basales glomérulaires par anticorps monoclonal).