Tubuloglomerular feedback.
Increasing evidence is accumulating that the tubuloglomerular feedback system exercises significant control over the glomerular filtration rate. We present our current understanding of the mechanisms underlying the operation of the TGF system and discuss several situations applicable to clinical medicine where altered TGF responses are likely to be manifested as perceivable changes in overall renal function.
Thomson
S C
SC
Department of Medicine, University of California, San Diego School of Medicine, Calif.
Blantz
R C
RC
D005246:Feedback; D006801:Humans; D007678:Kidney Glomerulus / Q000502:physiology*; D007684:Kidney Tubules / Q000502:physiology*