title: Preliminary observations on the results of combined temporary 192iridium implantation and external beam irradiation for carcinoma of the prostate.
abstract: We treated 43 patients with adenocarcinoma of the prostate confined to the pelvis with a combination of staging pelvic lymphadenectomy, temporary implantation of the prostate with 192iridium and external beam irradiation. The procedure was relatively safe with low early morbidity. However, there were significant late complications. Of these patients 29 had needle biopsy of the prostate 1 year after completion of therapy and 15 demonstrated residual tumor. Clinical stage C and poorly differentiated tumors were not well controlled.
authors.forename: P C
authors.initials: PC
authors.lastname: Bosch
authors.forename: K A
authors.initials: KA
authors.lastname: Forbes
authors.forename: S
authors.initials: S
authors.lastname: Prassvinichai
authors.forename: J B
authors.initials: JB
authors.lastname: Miller
authors.forename: H
authors.initials: H
authors.lastname: Golji
authors.forename: D C
authors.initials: DC
authors.lastname: Martin
mesh_terms: D000230:Adenocarcinoma / Q000532:radiotherapy*; D000368:Aged; D001918:Brachytherapy / Q000009:adverse effects; D003131:Combined Modality Therapy; D003556:Cystitis / Q000209:etiology; D007172:Erectile Dysfunction / Q000209:etiology; D005500:Follow-Up Studies; D006801:Humans; D007495:Iridium / Q000627:therapeutic use*; D008197:Lymph Node Excision / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000209:etiology*; D010388:Pelvis; D011183:Postoperative Complications / Q000209:etiology; D011349:Proctitis / Q000209:etiology; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D011868:Radioisotopes / Q000627:therapeutic use*; D011882:Radiotherapy, High-Energy / Q000009:adverse effects; D013997:Time Factors; D014549:Urinary Incontinence / Q000209:etiology; D014555:Urination Disorders / Q000209:etiology
chemical_list: D011868:Radioisotopes; D007495:Iridium