[A tumor-associated antigen of cervical cancer].
The tumour-associated antigen was identified with the aid of antisera obtained from rabbits immunized with 3 M KCl extract of pool human cervical carcinoma cells. The antigen was found in 92.5% specimens of human cervical squamous cell carcinoma, in 4.7% specimens of other localization of the tumours. The antigen was absent from sets of normal human tissues. The tumour-associated antigen was not identical with CEA, alpha-fetoprotein, SP1, EPA and lactoferrin and it was localized in cytoplasm of cervical carcinoma cells.
Ermoshina
N V
NV
Ievleva
E S
ES
Ageenko
A I
AI
Kogan
I Ia
IIa
Tsukerman
B G
BG
D000818:Animals; D000912:Antibodies, Neoplasm / Q000032:analysis; D000951:Antigens, Neoplasm / Q000032:analysis* / Q000276:immunology / Q000302:isolation & purification; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis*; D002584:Cervix Uteri / Q000276:immunology; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007106:Immune Sera / Q000302:isolation & purification; D007114:Immunization; D005779:Immunodiffusion; D009928:Organ Specificity; D011817:Rabbits; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis*
D000912:Antibodies, Neoplasm; D000951:Antigens, Neoplasm; D007106:Immune Sera
Opukholeassotsiirovannyĭ antigen raka sheĭki matki.