2-14C-mevalonate oxidation during rat development.
In vivo oxidation of 2-14C-mevalonate is very low in 1- to 3-day-old rats and then rises to adult levels. Kidney slices oxidize mevalonate at an equal rate during development. However, at the time of weaning the rate is transiently increased in male rats only.
Hahn
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D000375:Aging; D000818:Animals; D000833:Animals, Suckling; D002245:Carbon Dioxide / Q000378:metabolism; D002250:Carbon Radioisotopes; D005260:Female; D007668:Kidney / Q000254:growth & development / Q000378:metabolism; D008297:Male; D008798:Mevalonic Acid / Q000378:metabolism*; D010084:Oxidation-Reduction; D051381:Rats; D011919:Rats, Inbred Strains; D012737:Sex Factors; D014886:Weaning
D002250:Carbon Radioisotopes; D002245:Carbon Dioxide; D008798:Mevalonic Acid