title: Phosphorylation of Plasmodium berghei derived phosphoproteins associated with the host erythrocyte membrane by the spectrin kinase.
abstract: Plasmodium berghei derived phosphoproteins are associated with the host erythrocyte membrane. Effectors of the phosphorylation reaction regulate the phosphorylation of the P. berghei derived proteins and spectrin in a similar manner. The spectrin kinase also phosphorylates the P. berghei phosphoproteins in a reconstituted reaction at the same site(s) as the endogenously phosphorylated proteins. These results indicate that a host protein kinase may regulate parasite phosphoproteins during malaria.
authors.affiliation: MacArthur Center for Molecular Parasitology, Yale University School of Medicine, New Haven, CT 06510-8028.
authors.forename: M F
authors.initials: MF
authors.lastname: Wiser
mesh_terms: D000818:Animals; D002413:Cations, Divalent; D004163:Diphosphoglyceric Acids / Q000378:metabolism; D004910:Erythrocyte Membrane / Q000378:metabolism; D006790:Host-Parasite Interactions; D008565:Membrane Proteins / Q000378:metabolism; D051379:Mice; D010750:Phosphoproteins / Q000378:metabolism*; D010766:Phosphorylation; D010962:Plasmodium berghei / Q000378:metabolism*; D011494:Protein Kinases / Q000378:metabolism*
chemical_list: D002413:Cations, Divalent; D004163:Diphosphoglyceric Acids; D008565:Membrane Proteins; D010750:Phosphoproteins; D011494:Protein Kinases; C033464:spectrin kinase