title: Gene expression in amphibian embryogenesis.
abstract: The study of molecular events during the embryogenesis of Xenopus laevis has advanced as a result of the availability of molecular markers, i.e., nucleic acid and antibody probes for genes that are expressed in a temporally and spatially regulated fashion during development. In this article we summarize results on the localized expression of keratin genes and on the reconstruction of regulated transcription of the gastrula/neurula-specific DG42 gene. Furthermore, we discuss experiments that investigate molecular events during mesoderm induction and provide information on the nature of the inducing principle.
authors.affiliation: Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, Bethesda, MD 20892.
authors.forename: I B
authors.initials: IB
authors.lastname: Dawid
authors.forename: M L
authors.initials: ML
authors.lastname: Rebbert
authors.forename: F
authors.initials: F
authors.lastname: Rosa
authors.forename: M
authors.initials: M
authors.lastname: Jamrich
authors.forename: T D
authors.initials: TD
authors.lastname: Sargent
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D004627:Embryonic Induction; D005786:Gene Expression Regulation; D005819:Genetic Markers; D014982:Xenopus laevis / Q000196:embryology* / Q000378:metabolism
chemical_list: D005819:Genetic Markers