[Immunohistologic findings in paragangliomas in the area of the head and neck].
30 patients with paraganglioma of the head and neck region were subjected to surgery at the Department of Otorhinolaryngology during 1978-1985. Histological classification of the obtained specimens was performed using also immunocytochemical methods to detect more details. The site of origin of the tumours was the glomus tympanicum in 18 cases, 7 times the glomus caroticum and 5 times the glomus jugulare. Antibodies against neuronal components (S-100 protein), endothelial cells (UEAI) and endocrine activity (NSE) were used for subtyping by PAP-method (Figs. 1-3). Immunocytochemistry provided for an easy subtyping of the tumours and showed an increase in severe progress forms in adenomatous variants of paragangliomas.
Milewski
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Hals-Nasen-Ohrenklinik der Universität Mainz.
Dienes
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D000328:Adult; D000368:Aged; D004730:Endothelium, Vascular / Q000473:pathology; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D037102:Lectins / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D010235:Paraganglioma / Q000473:pathology*; D010751:Phosphopyruvate Hydratase / Q000378:metabolism*; D037121:Plant Lectins; D009418:S100 Proteins / Q000378:metabolism*
D037102:Lectins; D037121:Plant Lectins; D009418:S100 Proteins; C036850:Ulex europaeus lectins; D010751:Phosphopyruvate Hydratase
Immunhistologische Befunde bei Paragangliomen im Kopf-Hals-Bereich.