title: Hypergammaglobulinemic purpura in childhood. Report of two cases and review of the literature.
abstract: Hypergammaglobulinemic purpura is a rare syndrome characterized by long-standing recurrent purpura of the lower limbs, polyclonal hypergammaglobulinemia, increased erythrocyte sedimentation rate and high titer rheumatoid factor positivity. The syndrome can occur isolated or in association with a systemic disease. Few cases have been described in childhood. We report two cases together with a review of the paediatric literature.
authors.affiliation: Clinica Pediatrica, Università di Pavia, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Martini
authors.forename: A
authors.initials: A
authors.lastname: Ravelli
authors.forename: S
authors.initials: S
authors.lastname: Viola
authors.forename: P
authors.initials: P
authors.lastname: De Stefano
authors.forename: C
authors.initials: C
authors.lastname: Borgna
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000378:metabolism; D007074:Immunoglobulin G / Q000378:metabolism; D007075:Immunoglobulin M / Q000378:metabolism; D008297:Male; D008947:Mixed Connective Tissue Disease / Q000209:etiology; D011694:Purpura, Hyperglobulinemic / Q000150:complications / Q000175:diagnosis / Q000378:metabolism
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M