title: [In vitro studies of the tolerance of hydroxypropyl methylcellulose (HPMC) with regard to the human corneal endothelium].
abstract: The compatibility of hydroxypropylmethylcellulose (HPMC) was tested in vitro on 48 human donor corneas. Using a perfusion technique, the function of the corneal endothelium was recorded by stromal thickness measurements under light-microscopic control. The experiments showed that HPMC at a concentration of 0.5% is compatible for 3.5 hours of perfusion in the presence of human corneal endothelium.
authors.affiliation: Univ.-Augenklinik Zürich.
authors.forename: B
authors.initials: B
authors.lastname: Schimmelpfennig
mesh_terms: D000368:Aged; D002452:Cell Count / Q000187:drug effects; D016039:Corneal Transplantation; D046508:Culture Techniques; D004728:Endothelium, Corneal / Q000187:drug effects*; D006801:Humans; D065347:Hypromellose Derivatives; D008747:Methylcellulose / Q000031:analogs & derivatives* / Q000633:toxicity; D010477:Perfusion
chemical_list: D065347:Hypromellose Derivatives; D008747:Methylcellulose
vernacular_title: In vitro Untersuchungen über die Verträglichkeit von Hydroxypropylmethylcellulose (HPMC) gegenüber menschlichem Hornhautendothel.