Clofazimine in dermatitis ulcerosa (pyoderma gangrenosum). Open clinical trial.
Five patients suffering from dermatitis ulcerosa (a variant of pyoderma gangrenosum) were treated with clofazimine in a daily dosage of 200 mg orally. Complete healing was noted in 2 patients, partial response in 2, no effect in 1. Side effects were mild and transitory in form of a red coloring of the skin (all patients) and mild ichthyosis (2 patients).
Mensing
H
H
Universitäts-Hautklinik Hamburg-Eppendorf, BRD.
D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D002991:Clofazimine / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D005734:Gangrene; D006801:Humans; D008297:Male; D008875:Middle Aged; D011711:Pyoderma / Q000188:drug therapy* / Q000473:pathology; D012883:Skin Ulcer / Q000188:drug therapy*
D002991:Clofazimine