Morphological approach to the mechanism of heart failure.
From the ultrastructural aspects of the myocardial cell in different types of heart overloading, several points concerning the nature of the myofibrillar changes, the changes in volume, number and size of mitochondria, and the dependence of cellular lesions on the severity of the load were discussed.
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Unité de Recherches de Pathologie Cardio-vasculaire, INSERM U.2, Hôpital Léon Bernard, Limeil-Brévannes, France.
D000818:Animals; D006224:Cricetinae; D006333:Heart Failure / Q000473:pathology*; D008854:Microscopy, Electron; D009206:Myocardium / Q000473:pathology*; D009210:Myofibrils / Q000648:ultrastructure; D011817:Rabbits; D051381:Rats