title: Luteinizing hormone-releasing hormone induces thyroxine release together with testosterone in the neotenic axolotl Ambystoma mexicanum.
abstract: In male neotenic axolotls Ambystoma mexicanum plasma concentrations of thyroxine (T4) and testosterone were increased following intravenous injection of 10 micrograms luteinizing hormone-releasing hormone. A dose of 50 micrograms influenced only plasma T4 levels. This observation suggests for the first time that a hypothalamic hormone is capable of stimulating the thyroidal axis in the neotenic axolotl.
authors.affiliation: Laboratory of Comparative Endocrinology, Catholic University of Leuven, Belgium.
authors.forename: G F
authors.initials: GF
authors.lastname: Jacobs
authors.forename: E R
authors.initials: ER
authors.lastname: Kühn
mesh_terms: D000557:Ambystoma / Q000097:blood*; D000558:Ambystoma mexicanum / Q000097:blood*; D000818:Animals; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage / Q000494:pharmacology*; D007275:Injections, Intravenous; D007814:Larva / Q000378:metabolism; D008297:Male; D013739:Testosterone / Q000097:blood*; D013974:Thyroxine / Q000097:blood*
chemical_list: D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone; D013974:Thyroxine