title: Is the variational scope of individual sensitivity given enough consideration in evaluation of risks caused by toxicological substances in food?
abstract: The contemporary concept of evaluation of risks with humans caused by xenobiotics in food is critically reviewed. In this context it is pointed out that epidemiologic studies, in most cases, give little reliable evidence only. Mankind's risk factors are of a multi-dimensional composition, depending on genetic aspects and the differring health and nutrition statuses of the individuals. This leads to an enormously wide scope of variations in the individual sensitivity to xenobiotics. Contemporary knowledge leaves the question open, whether predisposed population groups are always sufficiently protected by the level of the permissible amount of xenobiotics.
authors.affiliation: Central Institute of Nutrition in Potsdam-Rehbrücke, Academy of Sciences of the GDR.
authors.forename: D W
authors.initials: DW
authors.lastname: Bleyl
mesh_terms: D005506:Food Contamination; D006801:Humans; D012307:Risk Factors