title: Issues related to in vitro operation of potentially implantable enzyme electrode glucose sensors.
abstract: The operation of enzyme electrode glucose sensors based on oxygen, hydrogen peroxide, and electron carrier molecules is reviewed. Issues that are most effectively addressed by in vitro experimentation are identified. An understanding of these issues is prerequisite for unequivocal interpretation of in vivo results.
authors.affiliation: Department of Applied Mechanics and Engineering Sciences, University of California, San Diego.
authors.forename: D A
authors.initials: DA
authors.lastname: Gough
mesh_terms: D015374:Biosensing Techniques; D004563:Electrochemistry; D004566:Electrodes; D004798:Enzymes; D005947:Glucose / Q000032:analysis*; D006861:Hydrogen Peroxide; D010100:Oxygen; D019736:Prostheses and Implants
chemical_list: D004798:Enzymes; D006861:Hydrogen Peroxide; D005947:Glucose; D010100:Oxygen