title: [Changes in the hormone profile, central hemodynamics and tissue blood flow in patients with thyrotoxic goiter during treatment with lithium carbonate].
abstract: The nature of hemocirculatory and hormonal changes were studied in 68 patients with toxic goiter during lithium carbonate therapy. Thyroxine (T4), triiodothyronine (T3) and thyrotropin (TTH) levels, function of the cardiovascular system, tissue blood flow and vascular permeability were investigated. A significant decrease in T4 and TTH levels in the hemocirculation was observed in thyrotoxicosis patients under the influence of lithium carbonate prompting the return of disturbed myocardial function to normal and rapid restoration of microcirculatory disorders (the isotonic nature of cardiac activity turned into isometric).
authors.forename: I M
authors.initials: IM
authors.lastname: Petrov
mesh_terms: D000328:Adult; D005260:Female; D006111:Graves Disease / Q000188:drug therapy*; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008094:Lithium / Q000627:therapeutic use*; D016651:Lithium Carbonate; D008297:Male; D008833:Microcirculation / Q000187:drug effects; D008875:Middle Aged; D013972:Thyrotropin / Q000097:blood*; D013974:Thyroxine / Q000097:blood*; D014284:Triiodothyronine / Q000097:blood*
chemical_list: D014284:Triiodothyronine; D016651:Lithium Carbonate; D013972:Thyrotropin; D008094:Lithium; D013974:Thyroxine
vernacular_title: Izmeneniia gormonal'nogo profilia, tsentral'noĭ gemodinamiki i ; tkanevogo krovotoka u bol'nykh tireotoksicheskim zobom vo vremia lecheniia karbonatom litiia.