[Problems of the current theory of polymorphonuclear leukocytes].
Neutrophil is an effector cell capable of intra- and extracellular secretion of biologically active substances which produce a variety of effects on the course of inflammation, stop or inhibit multiplication of bacteria, fungi, viruses, transformed or affected cells of the macroorganism. A wide spectrum of neutrophil functions, recorded both in aerobic and anaerobic conditions, is furnished by previously synthesized and accumulated substances which provide the neutrophil with functionally essential components as early as its entrance into tissues from blood. Being a potent killer of biological objects, neutrophil acts with rapid loss of component substances and eventually destroys itself. Enhanced RNA synthesis proceeding in affected cells and thought to provide their reparative capacity, in neutrophils is denied of this compensatory function for reasons still awaiting clarification. Once stimulated for a specific function, neutrophil reduces or loses its capacity for response to additional stimuli.
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D000818:Animals; D000937:Antigen-Antibody Reactions; D001770:Blood Bactericidal Activity; D002453:Cell Cycle; D002470:Cell Survival; D006801:Humans; D007249:Inflammation / Q000276:immunology; D009504:Neutrophils / Q000166:cytology / Q000276:immunology* / Q000378:metabolism; D010100:Oxygen / Q000097:blood
D010100:Oxygen
Nekotorye voprosy sovremmennogo ucheniia o polimorfnoiadernykh leĭkotsitakh.