title: Lectin Ulex europaeus agglutinin I specifically labels a subset of primary afferent fibers which project selectively to the superficial dorsal horn of the spinal cord.
abstract: To examine differential carbohydrate expression among different subsets of primary afferent fibers, several fluorescein-isothiocyanate conjugated lectins were used in a histochemical study of the dorsal root ganglion (DRG) and spinal cord of the rabbit. The lectin Ulex europaeus agglutinin I specifically labeled a subset of DRG cells and primary afferent fibers which projected to the superficial laminae of the dorsal horn. These results suggest that specific carbohydrates containing L-fucosyl residue is expressed selectively in small diameter primary afferent fibers which subserve nociception or thermoception.
authors.forename: K
authors.initials: K
authors.lastname: Mori
mesh_terms: D000818:Animals; D050260:Carbohydrate Metabolism; D016650:Fluorescein-5-isothiocyanate; D005452:Fluoresceins; D005727:Ganglia, Spinal / Q000378:metabolism*; D006651:Histocytochemistry; D037102:Lectins; D009475:Neurons, Afferent / Q000378:metabolism; D009619:Nociceptors / Q000378:metabolism; D037121:Plant Lectins; D011817:Rabbits; D013116:Spinal Cord / Q000378:metabolism*; D013861:Thiocyanates
chemical_list: D005452:Fluoresceins; D037102:Lectins; D037121:Plant Lectins; D013861:Thiocyanates; C036850:Ulex europaeus lectins; D016650:Fluorescein-5-isothiocyanate