title: [Shigella serotypes and drug resistance patterns of strains isolated in Etimesgut, Turkey, in 1987].
abstract: Drug resistance patterns of shigella strains were investigated in a prospective manner in Etimesgut district during a period of 1 year. Thirty strains shigella were isolated, belonged to three subgroups with preponderance of Sh. flexneri (70%), followed by Sh. sonnei (27%) and Sh. boydii (3%). The resistance was highest with streptomycin (80%), followed by trimethoprim-sulfamethoxazole (TMP-SMZ) (53%) and ampicillin (43%). Only three strains (10%) were sensitive to all eight antibiotics tested. Sixteen (53%) were resistant to three or more antibiotics. The data showed an increase in resistance to the commonly used antimicrobial agents--namely IMP-SMZ and ampicillin. IMP-SMZ is no longer the drug of choice in severe shigellosis, at least in this region of Turkey.
authors.affiliation: Iç Hastaliklari Uzmani, H.U. Etimesgut Bölge H., Ankara.
authors.forename: V
authors.initials: V
authors.lastname: Korten
authors.forename: A
authors.initials: A
authors.lastname: Mert
authors.forename: K
authors.initials: K
authors.lastname: Ovünç
authors.forename: M
authors.initials: M
authors.lastname: Ceyhan
authors.forename: S
authors.initials: S
authors.lastname: Acar
authors.forename: T
authors.initials: T
authors.lastname: Ulaş
mesh_terms: D000668:Ampicillin Resistance; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002443:Ceftriaxone / Q000494:pharmacology; D002702:Chloramphenicol Resistance; D004352:Drug Resistance, Microbial; D004405:Dysentery, Bacillary / Q000382:microbiology*; D006801:Humans; D009268:Nalidixic Acid / Q000494:pharmacology; D015242:Ofloxacin / Q000494:pharmacology; D011446:Prospective Studies; D012703:Serotyping; D012760:Shigella / Q000145:classification* / Q000187:drug effects; D012761:Shigella boydii / Q000145:classification / Q000187:drug effects; D012763:Shigella flexneri / Q000145:classification / Q000187:drug effects; D012764:Shigella sonnei / Q000145:classification / Q000187:drug effects; D013307:Streptomycin / Q000494:pharmacology; D013753:Tetracycline Resistance; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000494:pharmacology; D014421:Turkey
chemical_list: D000900:Anti-Bacterial Agents; D009268:Nalidixic Acid; D002443:Ceftriaxone; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D015242:Ofloxacin; D013307:Streptomycin
vernacular_title: Etimesgut bölgesinde 1987 yilinda izole edilen shigella serotipleri ve antibiyotik dirençleri.