title: [Nuclear medicine diagnostic localization in primary aldosteronism and Cushing syndrome].
abstract: The main indication for 131J-cholesterol scintigraphy is primary aldosteronism. The preoperative localization of aldosterone - producing adenomas may be obtained with the non-invasive NP-59 - scintigraphy in 75-85% of the patients. Idiopathic bilateral adrenal hyperplasia is diagnosed correctly in 90-100% of the cases. In Cushing's syndrome scintigraphy of the adrenal cortex is indicated only in specific cases such as very small adenomas, primary nodular adrenal hyperplasia and/or for the localization of ectopic adrenal cortex tissue. A false diagnosis may be caused by asymmetric uptake of the radioisotope in idiopathic bilateral hyperplasia or by unspecific absorption in non - adenomatous adrenal cortex tissue with symmetric uptake in patients with unilateral adenomas.
authors.affiliation: Department für Medizinische Radiologie, Universitätsspital Zürich, Schweiz.
authors.forename: G
authors.initials: G
authors.lastname: Sialer
authors.forename: B
authors.initials: B
authors.lastname: Marincek
authors.forename: T
authors.initials: T
authors.lastname: Mengden
authors.forename: W
authors.initials: W
authors.lastname: Vetter
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging; D000306:Adrenal Cortex Neoplasms / Q000000981:diagnostic imaging; D000311:Adrenal Glands / Q000000981:diagnostic imaging; D000314:Adrenal Rest Tumor / Q000000981:diagnostic imaging; D000308:Adrenocortical Hyperfunction / Q000000981:diagnostic imaging; D002784:Cholesterol / Q000031:analogs & derivatives; D003480:Cushing Syndrome / Q000000981:diagnostic imaging*; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism; D006929:Hyperaldosteronism / Q000000981:diagnostic imaging*; D007457:Iodine Radioisotopes; D011877:Radionuclide Imaging
chemical_list: D007457:Iodine Radioisotopes; C016523:6-iodocholesterol; D002784:Cholesterol; D006854:Hydrocortisone
vernacular_title: Nuklearmedizinische Lokalisationsdiagnostik bei primärem Aldosteronismus und Cushing-Syndrom.