[Amoxicillin-clavulanic acid combination in bacterial infections of the upper respiratory tract in childhood. Controlled clinical study].
A comparative clinical trial of amoxycillin - clavulanic acid combination versus erythromycin was carried out in a case series of 20 pediatric patients, suffering from upper respiratory tract infections with a proven bacterial etiology and different localization (tonsils, nasal and paranasal sinuses and ear). The results have confirmed the highly innovative efficacy of amoxycillin - clavulanic acid combination: the clinical judgement was in fact favourable, with eradication of the pathogenic agent in 90% of cases. The tolerability of the combination was globally good from both the general and local point of view.
Boccazzi
A
A
Clinica Pediatrica I dell'Università degli Studi di Milano, Italia.
Borzani
M
M
Scotti
L
L
D000208:Acute Disease; D000293:Adolescent; D000658:Amoxicillin / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D002969:Clavulanic Acids / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D004917:Erythromycin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010033:Otitis Media / Q000188:drug therapy*; D010035:Otitis Media, Suppurative / Q000188:drug therapy*; D011897:Random Allocation; D012852:Sinusitis / Q000188:drug therapy*; D014069:Tonsillitis / Q000188:drug therapy*
D002969:Clavulanic Acids; D004917:Erythromycin; D000658:Amoxicillin
L'associazione amoxicillina-acido clavulanico nelle infezioni batteriche delle vie respiratorie superiori in età pediatrica. Studio clinico controllato.