Mitomycin C and ethyl methanesulphonate-induced sister-chromatid exchanges in lymphocytes from individuals with Alzheimer's pre-senile dementia.
Baseline and mutagen-induced sister-chromatid exchange frequencies were compared in peripheral blood lymphocytes from patients with Alzheimer's pre-senile dementia and control individuals. No significant differences were found between the two groups.
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D000367:Age Factors; D000368:Aged; D000544:Alzheimer Disease / Q000235:genetics*; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D005020:Ethyl Methanesulfonate / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D016685:Mitomycin; D008937:Mitomycins / Q000494:pharmacology*; D009152:Mutagenicity Tests; D012854:Sister Chromatid Exchange / Q000187:drug effects*
D008937:Mitomycins; D016685:Mitomycin; D005020:Ethyl Methanesulfonate