title: [General tumor pathology and pathophysiology].
abstract: The clinical behaviour of malignancies is characterized by four stages of progressive development: local, locoregional, mono- or oligotop-distant, and disseminated-distant. In the first three stages surgery is the most effective means of treatment. The possibility of tumor cell dissemination and implantation within the surgical area determines the methods of oncological surgery (no touch, wide margins of clearance, en bloc resection together with lymph node dissection).
authors.affiliation: Abteilung für Klinische Pathologie, Chir. Univ. Klinik, Erlangen.
authors.forename: P
authors.initials: P
authors.lastname: Hermanek
mesh_terms: D006801:Humans; D009367:Neoplasm Staging; D009369:Neoplasms / Q000473:pathology* / Q000601:surgery; D011379:Prognosis
vernacular_title: Allgemeine Tumorpathologie und -pathophysiologie.