Eikenella corrodens in human mouth flora.
The incidence of Eikenella corrodens in the human mouth was studied in 229 individuals. Six (2.6%) had positive cultures. The incidence of positive cultures for the saliva group was 0.6% and for the tooth-scraping group it was 8.2%. When 11 isolates were tested against 33 antimicrobials by disc-agar diffusion, 82% were susceptible to penicillin, cephalothin, and cefoperazone. Susceptibility to the remaining second- and third-generation cephalosporins studied was 100%. We suggest that the use of a second- or third-generation cephalosporin only is appropriate empiric therapy for human bite injuries.
Rayan
G M
GM
Orthopaedic Surgery Department, University of Oklahoma Health Sciences Center, Oklahoma City.
Putnam
J L
JL
Cahill
S L
SL
Flournoy
D J
DJ
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001439:Bacteroides / Q000302:isolation & purification*; D002511:Cephalosporins / Q000494:pharmacology; D016124:Eikenella corrodens / Q000187:drug effects / Q000302:isolation & purification*; D006801:Humans; D009055:Mouth / Q000382:microbiology*; D012463:Saliva / Q000382:microbiology; D014070:Tooth / Q000382:microbiology
D000900:Anti-Bacterial Agents; D002511:Cephalosporins