title: Studies on the hexose region of the lipopolysaccharide from a low virulence strain of Salmonella typhimurium.
abstract: The structure of the hexose region of the lipopolysaccharide from M206 strain, a mutant of Salmonella typhimurium having reduced virulence, was partially determined. Immunological tests indicated cross-reactions of anti-(M206) antiserum with wild-type C5 and Ra mutant strains. Data obtained on chemical composition, periodate oxidation, acetolysis, methylation and analysis by gas chromatography/mass spectrometry show that M206 type lipopolysaccharide contains the common core polysaccharide of Salmonella which was substituted in position 4 of the subterminal glucose unit by a disaccharide: D-glucosyl 1----3 D-galactose. This substitution is probably related to the slight virulence of M206 strain.
authors.affiliation: Laboratoire de Biochimie Microbienne, UA CNRS 1176, Université Lyon I, Villeurbanne, France.
authors.forename: N
authors.initials: N
authors.lastname: dalla Venezia
authors.forename: M
authors.initials: M
authors.lastname: Bruneteau
authors.forename: P
authors.initials: P
authors.lastname: Binder
authors.forename: O
authors.initials: O
authors.lastname: Creach
authors.forename: R
authors.initials: R
authors.lastname: Fontanges
authors.forename: G
authors.initials: G
authors.lastname: Michel
mesh_terms: D000085:Acetates; D006601:Hexoses / Q000032:analysis*; D007120:Immunochemistry; D008070:Lipopolysaccharides / Q000032:analysis* / Q000276:immunology; D008745:Methylation; D010084:Oxidation-Reduction; D012486:Salmonella typhimurium / Q000032:analysis* / Q000276:immunology / Q000472:pathogenicity; D014774:Virulence / Q000235:genetics
chemical_list: D000085:Acetates; D006601:Hexoses; D008070:Lipopolysaccharides