Neuroendocrine effects on memory in aged rodents and humans.
Considerable evidence indicates that epinephrine regulates memory storage processing in young animals. Recent findings suggest that hyperglycemia subsequent to epinephrine release or injection may mediate the hormone's effects on memory. This paper reviews findings demonstrating that epinephrine and glucose treatments attenuate age-related memory impairments in rodents and humans. Additional results suggest that, in aged human and animal subjects, poor glucose regulation predicts memory performance of individual subjects.
Gold
P E
PE
Department of Psychology, University of Virginia, Charlottesville 22903.
Stone
W S
WS
D000375:Aging / Q000378:metabolism / Q000502:physiology*; D000818:Animals; D001786:Blood Glucose / Q000502:physiology*; D004837:Epinephrine / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D008568:Memory / Q000187:drug effects / Q000502:physiology*; D009490:Neurosecretory Systems / Q000378:metabolism / Q000502:physiology*; D051381:Rats
D001786:Blood Glucose; D004837:Epinephrine