title: Eicosanoids and platelet activating factor mechanisms in organ rejection.
abstract: In summary, the eicosanoids and PAF modulate the immune response in vitro and in vivo. The PG seem to attenuate and TX, LT, and PAF to potentiate the cell-mediated immune response. In addition, these compounds have nonimmunologic effects that may modify the edema and decreased blood flow associated with the rejection process.
authors.affiliation: Department of Surgery, Georgetown University Medical Center, Washington, DC 20007.
authors.forename: M L
authors.initials: ML
authors.lastname: Foegh
mesh_terms: D000818:Animals; D006084:Graft Rejection / Q000187:drug effects; D015289:Leukotrienes / Q000502:physiology*; D010972:Platelet Activating Factor / Q000502:physiology*; D011453:Prostaglandins / Q000502:physiology*; D013931:Thromboxanes / Q000502:physiology*
chemical_list: D015289:Leukotrienes; D010972:Platelet Activating Factor; D011453:Prostaglandins; D013931:Thromboxanes