[Prodrugs: goals, principles and outlook].
The review covers the principles of creation of prodrugs as a chemical system for delivering drugs to targets. It presents the strategy of prodrug design and describes the main approaches to creation of prodrugs for drugs of different classes: antibiotics, anti-inflammatory and antitumour agents, corticosteroids, agents of the central action, etc.
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D002626:Chemistry, Pharmaceutical; D015195:Drug Design; D006801:Humans; D011355:Prodrugs / Q000138:chemical synthesis / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D013329:Structure-Activity Relationship; D009626:Terminology as Topic
D011355:Prodrugs
Prolekarstva: tseli, printsipy i perspektivy.