[The connections between structure, pharmacokinetics and effects of glucocorticoids].
Corticosteroids above all have an influence on the metabolism of proteins, lipids and carbohydrates. Inflammatory and immunological reactions are suppressed. The effects are based on the induction of both primary and secondary responses. Examples in catabolic and anabolic reactions are described. The significance of bioavailability is illustrated and hints to discriminate the types of corticosteroids for therapeutic requirement are given.
Lutz
F
F
Institut für Pharmakologie und Toxikologie im Fachbereich Veterinärmedizin, Justus-Liebig-Universität Giessen.
D000818:Animals; D001682:Biological Availability; D005938:Glucocorticoids / Q000493:pharmacokinetics* / Q000494:pharmacology / Q000627:therapeutic use; D015394:Molecular Structure
D005938:Glucocorticoids
Zusammenhänge zwischen Struktur, Pharmakokinetik und Wirkung der Glukokortikoide.