[Echoscopic diagnosis of the heterozygote carrier state in Duchenne's muscular dystrophy].
Skeletal muscles were subjected to echoscopy in order to detect the heterozygote carriers of Duchenne muscular dystrophy. The data were compared to the biochemical test--detection of serum creatine kinase activity. Echoscopy of 15 obligatory carriers and 47 control females yielded the test sensitivity of 53% and specificity of 94%. The use of both techniques is suggested.
Krasil'nikov
V V
VV
Lazebnik
T A
TA
Prokof'ev
G V
GV
D000328:Adult; D004796:Clinical Enzyme Tests; D003402:Creatine Kinase / Q000097:blood; D005069:Evaluation Studies as Topic; D005260:Female; D006580:Genetic Carrier Screening / Q000379:methods*; D008040:Genetic Linkage; D006801:Humans; D008875:Middle Aged; D009132:Muscles / Q000473:pathology; D009136:Muscular Dystrophies / Q000175:diagnosis* / Q000235:genetics; D014463:Ultrasonography; D014960:X Chromosome
D003402:Creatine Kinase
Ekhoskopicheskaia diagnostika geterozigotnogo nositel'stva myshechnoĭ distrofii Diushenna.