Contrast media for angiography: effect on renal function.
A total of 125 patients with severe peripheral vascular disease were examined with translumbar aortography. The mean dose of contrast medium injected was 65 ml of Angio Conray (containing 31.2 g of iodine). Forty patients were pretreated with mannitol, and 32 received furosemide. Thirty-eight patients (30%) had diabetes and, presumably, diabetic nephropathy. Eleven of them had significant azotemia (creatinine values greater than or equal to 4 mg/dl). Administration of contrast material did not significantly reduce renal function in any patient group. We conclude that acute renal failure following the injection of contrast material is uncommon, is reversible, and almost always occurs when avoidable complicating factors are present.
Cruz
C
C
Hricak
H
H
Samhouri
F
F
Smith
R F
RF
Eyler
W R
WR
Levin
N W
NW
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000792:Angiography; D001806:Blood Urea Nitrogen; D003404:Creatinine / Q000097:blood; D003925:Diabetic Angiopathies / Q000097:blood / Q000000981:diagnostic imaging / Q000503:physiopathology; D003928:Diabetic Nephropathies / Q000097:blood / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D005665:Furosemide / Q000008:administration & dosage; D006801:Humans; D007483:Iothalamic Acid / Q000008:administration & dosage / Q000009:adverse effects*; D007668:Kidney / Q000187:drug effects* / Q000503:physiopathology; D008297:Male; D008353:Mannitol / Q000008:administration & dosage; D008875:Middle Aged; D014652:Vascular Diseases / Q000097:blood / Q000000981:diagnostic imaging / Q000503:physiopathology
D007483:Iothalamic Acid; D008353:Mannitol; D005665:Furosemide; D003404:Creatinine