Inhibition of the release of a neutrophil chemotactic factor from macrophages partially explains the anti-inflammatory action of glucocorticoids.
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D015772:4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; D000818:Animals; D000893:Anti-Inflammatory Agents; D002630:Chemotactic Factors / Q000378:metabolism*; D003907:Dexamethasone / Q000494:pharmacology; D005938:Glucocorticoids / Q000494:pharmacology*; D066298:In Vitro Techniques; D007213:Indomethacin / Q000494:pharmacology; D016209:Interleukin-8; D008070:Lipopolysaccharides / Q000494:pharmacology; D008264:Macrophages / Q000187:drug effects / Q000378:metabolism*; D010537:Peritoneum / Q000166:cytology; D011720:Pyrazoles / Q000494:pharmacology; D051381:Rats; D014462:Ultrafiltration
D000893:Anti-Inflammatory Agents; D002630:Chemotactic Factors; D005938:Glucocorticoids; D016209:Interleukin-8; D008070:Lipopolysaccharides; D011720:Pyrazoles; D015772:4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; D003907:Dexamethasone; D007213:Indomethacin