title: Growth and growth hormone secretion.
abstract: Growth hormone pulse amplitude is intimately connected with growth in childhood. Its effects are most clear in middle childhood, although the influence of adrenal androgens is probably also important. In infancy, nutrition plays an important part and, in the adolescent growth spurt, the synergism with sex steroids is important. Detailed attention needs now to be focussed on the mechanisms by which growth hormone is secreted and has its action; these include the effects of GHRH, somatostatin, insulin and IGF-I.
authors.affiliation: Endocrine Unit, Cobbold Laboratories, Middlesex Hospital, London.
authors.forename: C G
authors.initials: CG
authors.lastname: Brook
authors.forename: P C
authors.initials: PC
authors.lastname: Hindmarsh
authors.forename: R
authors.initials: R
authors.lastname: Stanhope
mesh_terms: D000293:Adolescent; D002648:Child; D002657:Child Development / Q000502:physiology; D005260:Female; D006128:Growth; D013006:Growth Hormone / Q000378:metabolism*; D006801:Humans; D007223:Infant; D008297:Male
chemical_list: D013006:Growth Hormone