Primary structure of the alpha-subunit of bovine adenylate cyclase-stimulating G-protein deduced from the cDNA sequence.
The primary structure of the alpha-subunit of the adenylate cyclase-stimulating G-protein (Gs) has been deduced from the nucleotide sequence of cloned DNA complementary to the bovine cerebral mRNA encoding the polypeptide. Comparison of the amino acid sequences of the alpha-subunits of Gs and transducin reveals that some of the highly conserved regions show sequence homology with elongation factor-Tu and ras p21 proteins and correspond to functional regions of guanine nucleotide-binding proteins.
Nukada
T
T
Tanabe
T
T
Takahashi
H
H
Noda
M
M
Hirose
T
T
Inayama
S
S
Numa
S
S
D000262:Adenylyl Cyclases / Q000378:metabolism; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002417:Cattle; D002540:Cerebral Cortex; D004247:DNA / Q000235:genetics; D004789:Enzyme Activation; D019204:GTP-Binding Proteins / Q000235:genetics*
D004247:DNA; D019204:GTP-Binding Proteins; D000262:Adenylyl Cyclases