Cerebral abnormalities in the Neu-Laxova syndrome.
Cerebral abnormalities are considered an obligatory manifestation of the Neu-Laxova syndrome and include lissencephaly, severe microcephaly, aplasia of the corpus callosum, hypoplasia of the cerebellum, and other pathological changes. We present data on 3 cases with central nervous system anomalies, two of which have not been described previously, and summarize the literature on the subject. The problem of distinguishing type III lissencephaly is discussed.
Ostrovskaya
T I
TI
Minsk Branch Institute of Medical Genetics, USSR.
Lazjuk
G I
GI
D000015:Abnormalities, Multiple / Q000145:classification / Q000235:genetics / Q000473:pathology*; D001921:Brain / Q000002:abnormalities*; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008831:Microcephaly / Q000235:genetics; D013577:Syndrome