Congenital hydrocephalus secondary to prenatal intracranial haemorrhage.
A high incidence of intracranial haemorrhage in utero of uncertain aetiology has been previously identified as an important cause of stillbirth in infants of immigrant Pacific Islanders in New Zealand. Congenital hydrocephalus is now described as a consequence of intracranial haemorrhage in 2 stillborn Pacific Islander infants. A large intracerebral haemorrhage, hydrocephalus and hydrops in one infant was first recognized prenatally by ultrasonography and caused intrauterine death at 26 weeks' gestation. Severe hydrocephalus in the other infant was first identified just before labour at term but the pathological findings were of old intraventricular haemorrhage with narrowing of the aqueduct of Sylvius as a reaction to the haemorrhage. Prior intracranial haemorrhage may be the cause of an increased incidence of hydrocephalus in Pacific Islander stillbirths and of some otherwise unexplained cases of congenital hydrocephalus in other races.
Gunn
T R
TR
Department of Paediatrics, University of Auckland School of Medicine, New Zealand.
Mora
J D
JD
Becroft
D M
DM
D002543:Cerebral Hemorrhage / Q000150:complications* / Q000175:diagnosis; D005260:Female; D005315:Fetal Diseases / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008636:Mesencephalon / Q000648:ultrastructure; D011247:Pregnancy; D014463:Ultrasonography