Duplex sonography of the breast.
A commercially available duplex ultrasound unit was used to examine 54 breast lesions in 44 women. The 7.5 MHz imaging probe contained a 3 MHz pulsed Doppler crystal, and the 10 MHz imaging probe contained a 4.5 MHz pulsed Doppler crystal. Doppler signals were elicited from normal breast tissue in only one patient. No Doppler signals were found in the five cysts examined in this study. For the 35 solid masses with biopsy or adequate follow-up that were examined with one or both probes, the sensitivity of Doppler for the diagnosis of carcinoma was 69%, the specificity 59%, positive predictive value 50%, negative predictive value 76%, and the accuracy 63%. Because of intermittent malfunction of the 10/4.5 MHz probe, some patients were examined with only the lower frequency probe. For the 34 solid lesions with biopsy or adequate follow-up that were examined with the 7.5/3 MHz probe, the sensitivity was 62%, specificity 38%, positive predictive value 50%, negative predictive value 72%, and accuracy 62%.
Jackson
V P
VP
Department of Radiology, Indiana University School of Medicine, Indianapolis 46202.
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000175:diagnosis* / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D011237:Predictive Value of Tests; D014463:Ultrasonography / Q000295:instrumentation / Q000379:methods*