title: Enteral versus parenteral nutrition: comparison of energy metabolism in lean and moderately obese women.
abstract: Continuous respiratory-exchange measurements were performed on ten moderately obese and ten lean young women for 1 h before, 3 h during, and 3 h after either parenteral (IV) or intragastric (IG) administration of a nutrient mixture infused at twice the postabsorptive, resting energy expenditure (REE). REE rose significantly from 0.98 +/- 0.02 to 1.13 +/- 0.03 kcal/min (IV) and from 0.99 +/- 0.02 to 1.13 +/- 0.02 kcal/min (IG) in the lean group; from 1.10 +/- 0.02 to 1.27 +/- 0.03 kcal/min (IV) and from 1.11 +/- 0.02 to 1.29 +/- 0.03 (IG) in the obese group. These increases resulted in similar nutrient-induced thermogenesis of 10.0 +/- 0.7% (IV) and 9.3 +/- 0.9% (IG) in the lean group; of 9.2 +/- 0.7%  (IV) and 10.1 +/- 0.8% (IG) in the obese. Nutrient utilization was comparable in both groups and in both routes of administration, although the response time to IG feeding was delayed. These results showed no significant difference in both the thermogenic response and nutrient utilization between moderately obese and control groups using acute IV or IG feeding.
authors.forename: O
authors.initials: O
authors.lastname: Vernet
authors.forename: L
authors.initials: L
authors.lastname: Christin
authors.forename: Y
authors.initials: Y
authors.lastname: Schutz
authors.forename: E
authors.initials: E
authors.lastname: Danforth
authors.forename: E
authors.initials: E
authors.lastname: Jéquier
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D001833:Body Temperature Regulation; D004041:Dietary Fats / Q000008:administration & dosage / Q000378:metabolism; D004044:Dietary Proteins / Q000008:administration & dosage / Q000378:metabolism; D002149:Energy Intake; D004734:Energy Metabolism; D004750:Enteral Nutrition; D005260:Female; D005947:Glucose / Q000008:administration & dosage / Q000378:metabolism; D006339:Heart Rate; D006801:Humans; D007328:Insulin / Q000097:blood; D009765:Obesity / Q000378:metabolism*; D010101:Oxygen Consumption; D010288:Parenteral Nutrition
chemical_list: D001786:Blood Glucose; D004041:Dietary Fats; D004044:Dietary Proteins; D007328:Insulin; D005947:Glucose