Intrahepatic bile duct strictures after human orthotopic liver transplantation. Recurrence of primary sclerosing cholangitis or unusual presentation of allograft rejection?
One of 55 patients transplanted for sclerosing cholangitis during the cyclosporin-steroid era (March 1980-June 1986) developed intrahepatic biliary strictures in the absence of allograft rejection within the 1st year posttransplantation. Although many causes underlie biliary pathology in the postoperative period (i.e., arterial injury, ischemia, chronic rejection, cholangitis), recurrent disease remains a possibility.
Lerut
J
J
Department of Surgery, University Health Center of Pittsburgh, PA 15213.
Demetris
A J
AJ
Stieber
A C
AC
Marsh
J W
JW
Gordon
R D
RD
Esquivel
C O
CO
Iwatsuki
S
S
Starzl
T E
TE
D000328:Adult; D001653:Bile Ducts, Intrahepatic / Q000473:pathology*; D015209:Cholangitis, Sclerosing / Q000175:diagnosis* / Q000628:therapy; D003251:Constriction, Pathologic / Q000175:diagnosis; D003937:Diagnosis, Differential; D006084:Graft Rejection; D006801:Humans; D008099:Liver / Q000473:pathology; D016031:Liver Transplantation; D008297:Male; D012008:Recurrence; D013997:Time Factors