Importance of the DNA repair enzyme O6-alkyl guanine alkyltransferase (AT) in cancer chemotherapy.
D'Incalci
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Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy.
Citti
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Taverna
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Catapano
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CV
D000477:Alkylating Agents / Q000494:pharmacology*; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D004260:DNA Repair; D006801:Humans; D008780:Methyltransferases / Q000378:metabolism*; D009369:Neoplasms / Q000188:drug therapy* / Q000201:enzymology; D009607:Nitrosourea Compounds / Q000494:pharmacology*; D019853:O(6)-Methylguanine-DNA Methyltransferase; D013045:Species Specificity
D000477:Alkylating Agents; D000970:Antineoplastic Agents; D009607:Nitrosourea Compounds; D008780:Methyltransferases; D019853:O(6)-Methylguanine-DNA Methyltransferase