Transplantation of human embryonic nerve tissue into a schizophrenic's brain.
Inspired by current knowledge of the possible participation of monoamines in the origin of schizophrenia and by experimental experience with embryonic nerve tissue transplantations, the authors ventured implantation of a human embryo's nervous tissue into a schizophrenic's brain. Six cubic millimeters of the transplant were placed in the septal area of both hemispheres. The substantial improvement of the clinical picture and, particularly, distinct improvement of memory abilities in the patient can more likely be attributed to the effect of the transplant rather than to the simultaneous mechanical intervention in the target structure of the recipient's brain.
Kolarík
J
J
Research Institute of Higher Nervous Activity, Palacký University, Olomoue, Czechoslovakia.
Nádvorník
P
P
Tabarka
K
K
Dvorák
M
M
Rozhold
O
O
D000328:Adult; D004298:Dopamine / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D009416:Nerve Regeneration; D009420:Nervous System / Q000637:transplantation*; D012559:Schizophrenia / Q000601:surgery*; D012565:Schizophrenic Psychology; D012688:Septum Pellucidum / Q000601:surgery*; D012701:Serotonin / Q000502:physiology*; D013238:Stereotaxic Techniques
D012701:Serotonin; D004298:Dopamine