title: The effect of topically applied fluorescein on fluorescent monoclonal antibodies in the diagnosis of chlamydial conjunctivitis.
abstract: Fluorescein-conjugated monoclonal antibodies have now been developed for use in the diagnosis of chlamydial conjunctivitis. This article discusses a clinical trial involving the use of such antibodies. We found that topical application of fluorescein before obtaining a specimen did not result in a statistically significant rate of false positives in a control group of patients.
authors.affiliation: Department of Ophthalmology, University of Wisconsin Medical School, Madison.
authors.forename: M P
authors.initials: MP
authors.lastname: Vrabec
authors.forename: P J
authors.initials: PJ
authors.lastname: McCanna
mesh_terms: D000287:Administration, Topical; D000911:Antibodies, Monoclonal; D002690:Chlamydia Infections / Q000175:diagnosis*; D002692:Chlamydia trachomatis; D002986:Clinical Trials as Topic; D003231:Conjunctivitis / Q000175:diagnosis*; D005452:Fluoresceins; D005455:Fluorescent Antibody Technique; D006801:Humans
chemical_list: D000911:Antibodies, Monoclonal; D005452:Fluoresceins