The effect of topically applied fluorescein on fluorescent monoclonal antibodies in the diagnosis of chlamydial conjunctivitis.
Fluorescein-conjugated monoclonal antibodies have now been developed for use in the diagnosis of chlamydial conjunctivitis. This article discusses a clinical trial involving the use of such antibodies. We found that topical application of fluorescein before obtaining a specimen did not result in a statistically significant rate of false positives in a control group of patients.
Vrabec
M P
MP
Department of Ophthalmology, University of Wisconsin Medical School, Madison.
McCanna
P J
PJ
D000287:Administration, Topical; D000911:Antibodies, Monoclonal; D002690:Chlamydia Infections / Q000175:diagnosis*; D002692:Chlamydia trachomatis; D002986:Clinical Trials as Topic; D003231:Conjunctivitis / Q000175:diagnosis*; D005452:Fluoresceins; D005455:Fluorescent Antibody Technique; D006801:Humans
D000911:Antibodies, Monoclonal; D005452:Fluoresceins