title: [Necrotizing enteritis during the therapeutic induction phase in leukemia. Value of surgical treatment].
abstract: A case of typhlitis in a 3,5 year old girl, during induction therapy for acute lymphoblastic leukemia is reported. This typhlitis, or necrotizing enterocolitis involving the coecum and right colon resulted in stercoral peritonitis during the neutropenic phase. After surgery, the patient had a favorable outcome with complete recovery. Knowledge about this uncommon but severe complication of hemopathies leads to follow clinical, microbiologic and radiologic rules of prophylaxis and screening. Typhlitis requires early treatment by supportive care and surgical cure if necessary.
authors.affiliation: Service de pédiatrie B, Hôpital des Enfants, Bordeaux, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Perel
authors.forename: F
authors.initials: F
authors.lastname: Ceccato
authors.forename: P
authors.initials: P
authors.lastname: Bucco
authors.forename: J F
authors.initials: JF
authors.lastname: Chateil
authors.forename: M
authors.initials: M
authors.lastname: Micheau
authors.forename: R
authors.initials: R
authors.lastname: Barbier
authors.forename: J M
authors.initials: JM
authors.lastname: Guillard
mesh_terms: D002675:Child, Preschool; D004761:Enterocolitis, Pseudomembranous / Q000209:etiology* / Q000601:surgery; D005260:Female; D006801:Humans; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000188:drug therapy; D012074:Remission Induction
vernacular_title: Entérite nécrosante à la phase d'induction thérapeutique d'une leucémie. Intérêt du traitement chirurgical.