Typhus-induced facial necrosis.
A patient with open wounds on his hands developed a severe case of typhus following exposure to a wild rabbit. Typhus resulted in extensive necrosis of the mid-face, including the nasal alae, pinna, and lips. The patient also sustained extensive extremity necrosis. A brief review of the epidemiology, pathophysiology, and treatment of this cause of facial necrosis is presented, as well as a discussion of dopamine gangrene. While this uncommon entity probably played a large part in the necrosis of this patient's extremities, these peripheral lesions are also compatible with typhus.
Wolfman
D E
DE
Fenton
W
W
Donald
P J
PJ
D000328:Adult; D000818:Animals; D005145:Face / Q000473:pathology*; D006801:Humans; D008046:Lip / Q000473:pathology; D008297:Male; D009336:Necrosis; D009666:Nose / Q000473:pathology; D011817:Rabbits; D013997:Time Factors; D014438:Typhus, Epidemic Louse-Borne / Q000473:pathology* / Q000635:transmission