New membrane for cell encapsulation.
A new membrane for microencapsulation of Langerhans islets is proposed. To obtain good biocompatibility properties, the membrane is prepared from polyethyleneimine, with heparin and protamine sulfate added. Investigation of the permeability of the membrane was based on Fick's law of the diffusion into and out of a sphere. It was observed that glucose and insulin easily diffuse into and out of microcapsules. Membrane itself is not permeable for human albumin and gamma-globulins.
Tatarkiewicz
K
K
Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw.
D001798:Blood Proteins / Q000032:analysis; D004339:Drug Compounding; D005947:Glucose / Q000032:analysis; D007328:Insulin / Q000032:analysis; D008422:Materials Testing / Q000379:methods; D008567:Membranes, Artificial; D010539:Permeability
D001798:Blood Proteins; D007328:Insulin; D008567:Membranes, Artificial; D005947:Glucose