title: Ceftriaxone penetration of tissues.
abstract: Ceftriaxone (Rocephin) has shown excellent tissue and body fluid penetration after a dose of 1-2 g: concentrations well above the minimal inhibitory concentrations of most pathogens responsible for infection are detectable for more than 24 h. Data from over 60 tissues were analyzed from the literature; a selection of comparative and noncomparative studies of clinical relevance is presented.
authors.affiliation: Professional Services Department, Hoffmann-La Roche Inc., Nutley, N.J.
authors.forename: S A
authors.initials: SA
authors.lastname: Billstein
mesh_terms: D002437:Cefazolin / Q000493:pharmacokinetics; D002443:Ceftriaxone / Q000008:administration & dosage / Q000493:pharmacokinetics*; D004333:Drug Administration Routes; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D014018:Tissue Distribution
chemical_list: D002443:Ceftriaxone; D002437:Cefazolin