Some epithelial metabolic factors affecting airway smooth muscle.
Airway epithelium contains multiple mechanisms for affecting airway smooth muscle tone and responsiveness. Inflammatory diseases of the airways exhibit extensive changes in the epithelium. Thus, alterations of airway epithelium may play important roles in the pathogenesis of bronchospasm in disease states.
Nadel
J A
JA
Cardiovascular Research Institute, University of California, San Francisco 94143-0130.
D002450:Cell Communication; D010450:Endopeptidases / Q000378:metabolism; D004848:Epithelium / Q000201:enzymology / Q000502:physiology; D006801:Humans; D009130:Muscle, Smooth / Q000201:enzymology / Q000502:physiology*; D012143:Respiratory Physiological Phenomena; D012137:Respiratory System / Q000201:enzymology
D010450:Endopeptidases