Relationship between serologic recognition of Escherichia coli 0111:B4 (J5) and clinical coliform mastitis in cattle.
Serum IgG1 ELISA titers recognizing gram-negative core antigens (Escherichia coli [J5]) were studied at a large dairy in central California. Population mean log10 titer was 2.7357 (equivalent to 1:544) with a SE of 0.03843. Titers increased with increased lactation number (unstandardized regression coefficient = 0.06733). Changes in lactation number accounted for only 6.77% of titer variation. Titers less than 1:240 were associated with 5.33 times the risk of clinical coliform mastitis. Also, older cattle were at greater risk to develop clinical coliform mastitis. These factors apparently affect incidence in a nonlinear fashion, with greatly increased risk associated with titers less than 1:240 and with fourth or greater lactations.
Tyler
J W
JW
Department of Clinical Pathology, School of Veterinary Medicine, University of California, Davis 95616.
Cullor
J S
JS
Osburn
B I
BI
Bushnell
R B
RB
Fenwick
B W
BW
D000367:Age Factors; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D004926:Escherichia coli / Q000276:immunology*; D004927:Escherichia coli Infections / Q000276:immunology / Q000662:veterinary*; D005260:Female; D007074:Immunoglobulin G / Q000096:biosynthesis* / Q000276:immunology; D007774:Lactation / Q000276:immunology*; D008414:Mastitis, Bovine / Q000276:immunology*; D011247:Pregnancy; D012044:Regression Analysis
D007074:Immunoglobulin G