title: Glucosamine is a normal component of liver glycogen.
abstract: There have been several reports of the incorporation of glucosamine into liver glycogen by an intraperitoneal injection of galactosamine, but it has not previously been considered that glucosamine is a normal component of liver glycogen. We now report that glucosamine occurs endogenously in rabbit- and pig-liver glycogens in the amount of about 1 nmol per 10 mg glycogen. Like the glucosamine incorporated by exogenous administration of galactosamine, the endogenous glucosamine takes the place of 1,4-linked alpha-glucose residues. It is found in both the outer and inner chains of the glycogen molecule.
authors.forename: B R
authors.initials: BR
authors.lastname: Kirkman
authors.forename: W J
authors.initials: WJ
authors.lastname: Whelan
mesh_terms: D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D005087:Glucan 1,4-alpha-Glucosidase; D005944:Glucosamine / Q000031:analogs & derivatives / Q000032:analysis*; D007553:Isotope Labeling; D008112:Liver Glycogen / Q000032:analysis*; D008745:Methylation; D011817:Rabbits; D013552:Swine; D000516:alpha-Amylases
chemical_list: D008112:Liver Glycogen; C047635:N-methylglucosamine; D000516:alpha-Amylases; D005087:Glucan 1,4-alpha-Glucosidase; D005944:Glucosamine