title: [Diagnosis and treatment of aplastic anemia].
abstract: Severe aplastic anemia is a rare disorder in childhood. Among various therapeutical strategies bone marrow transplantation (BMT) and immunosuppressive treatment with antithymocyte globulin (ATG) have proven to be most successful. Priority should be given to BMT over ATG treatment for patients with HLA-identical donors. Patients with Fanconi's anemia require a reduced conditioning program with cyclophosphamide and irradiation for BMT. Own experiences indicate that cooperative studies are highly needed to improve medical care for patients with severe aplastic anemia.
authors.affiliation: Abteilung Kinderheilkunde II, Universitäts-Kinderklinik und Poliklinik Ulm.
authors.forename: E
authors.initials: E
authors.lastname: Kleihauer
mesh_terms: D000741:Anemia, Aplastic / Q000175:diagnosis / Q000628:therapy*; D000961:Antilymphocyte Serum / Q000627:therapeutic use; D016026:Bone Marrow Transplantation; D002648:Child; D005199:Fanconi Anemia / Q000628:therapy; D006801:Humans; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D000961:Antilymphocyte Serum
vernacular_title: Diagnostik und Behandlung der aplastischen Anämie.