[Nifedipine therapy in uncomplicated essential hypertension and hypertensive problem cases].
In altogether 54 patients with high blood pressure of the clinical degrees of severity I-IV the blood pressure-reducing effectiveness of the calcium antagonist nifedipine was investigated both in the framework of an oral long-term therapy and especially in problematic situations of high blood pressure. According to the results of own treatment nifedipine is particularly suited for the antihypertensive combination therapy with beta-receptor blockers. Monotherapeutically favourable possibilities of application exist in hypokinetic types of the regulation of circulation as well as in elderly hypertensives. Therapy-resistant as well as crisis-like developments of high blood pressure react with excessive, well tolerable and persisting reductions of blood pressure. Above all with regard to this still little considered indication in the meantime nifedipine represents an unavoidable enrichment in the therapeutic basis spectre of the hypertonus.
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Abteilung für Kardiologie, Medizinischen Akademie Erfurt.
Oltmanns
G
G
Knappe
J
J
Holtz
H
H
Richard
F
F
D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000627:therapeutic use*; D011412:Propanolamines / Q000627:therapeutic use
D011412:Propanolamines; C011550:talinolol; D009543:Nifedipine
Nifedipin-Therapie bei unkomplizierter essentieller Hypertonie und Hochdruck-Problemfällen.