Auxological and biochemical assessment of short stature.
Measurements of height and calculation of height velocity are highly accurate and sensitive to changes in a child's health. Definition of normality must be based on height velocity, and it is not acceptable to label a child as short and normal purely on the basis of a biochemical test unless this is substantiated with the demonstration of a normal height velocity. Response to therapy is dependent on the child's pretreatment growth rate and also on the amount of GH administered and the frequency of administration.
Hindmarsh
P C
PC
Endocrine Unit, Middlesex Hospital, London.
Brook
C G
CG
D001827:Body Height; D002648:Child; D002675:Child, Preschool; D006130:Growth Disorders / Q000175:diagnosis*; D013006:Growth Hormone / Q000378:metabolism*; D006801:Humans; D007328:Insulin; D007334:Insulin-Like Growth Factor I / Q000097:blood
D007328:Insulin; D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone