[Molsidomine and isosorbide dinitrate:/their comparative effectiveness in patients with exertion-induced stenocardia].
The markedness and duration of antianginal effects of 2 mg molsidomine and 10 mg isosorbide dinitrate were compared by means of repeated treadmill tests in 37 coronary patients with stable angina of effort. Peak magnitude of the effect was similar with both drugs, while the duration of the effect of isosorbide dinitrate (4.0 +/- 0.3 hrs) was significantly greater than that of molsidomine (3.4 +/- 0.3 hrs). Molsidomine reached its peak effect significantly earlier, as compared to isosorbide dinitrate. There was a significant correlation between the effectiveness of molsidomine and isosorbide dinitrate in the same patients.
Martsevich
S Iu
SIu
Metelitsa
V I
VI
D000787:Angina Pectoris / Q000188:drug therapy* / Q000209:etiology; D002986:Clinical Trials as Topic; D006801:Humans; D007548:Isosorbide Dinitrate / Q000627:therapeutic use*; D008981:Molsidomine / Q000627:therapeutic use*; D005082:Physical Exertion; D010919:Placebos
D010919:Placebos; D008981:Molsidomine; D007548:Isosorbide Dinitrate
Molsidomin i izosorbid dinitrat: sravnenie effektivnosti u bol'nykh so stenokardiei napriazheniia.