[Changes in the hemodynamics and cardiac function of hypertension patients on moderate limited consumption of table salt].
A total of 50 patients with essential hypertension, I-II stages, were investigated to study changes in peripheral and intracardiac hemodynamics and myocardial contractility in moderate restriction of sodium chloride in "salt-sensitive" patients (SSP). In such patients (84% of all examinees) with mild arterial hypertension moderate restriction of SC consumption causes a sufficient antihypertensive effect determined by considerable improvement of peripheral hemodynamic indices and improvement of myocardial pump function and contractility, and in patients with moderate and severe hypertension it potentiates an antihypertensive effect and influence of drug therapy on hemodynamics. In non-SSP moderate restriction in SC consumption was ineffective. A sufficient antihypertensive effect in them resulted from the use of drug therapy at higher dosage than in SSP.
Bakhshaliev
A B
AB
Gadzhiev
R F
RF
Lan'shina
O E
OE
D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use; D002216:Captopril / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004039:Diet, Sodium-Restricted; D005260:Female; D006321:Heart / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000503:physiopathology* / Q000628:therapy / Q000652:urine; D008297:Male; D008875:Middle Aged; D011224:Prazosin / Q000627:therapeutic use; D012964:Sodium / Q000652:urine; D012965:Sodium Chloride
D000959:Antihypertensive Agents; D012965:Sodium Chloride; D002216:Captopril; D012964:Sodium; D011224:Prazosin
Izmenenie gemodinamiki i funktsional'nogo sostoianiia serdtsa pri umerennom ogranichenii potrebleniia povarennoĭ soli u bol'nykh gipertonicheskoĭ bolezn'iu.