The effect of intravesically administered Cetiprin on bladder spasms after transurethral resection of the prostate. A double-blind randomized study.
A double-blind study of the short-term effects of intravesically administered emepronium bromide (Cetiprin) versus placebo on bladder spasms after transurethral prostatectomy was done in 40 male patients. In the Cetiprin group there was a significant decline in the need for analgesia, and significantly fewer catheter problems. The use of intravesically instilled Cetiprin is recommended only in cases of severe postoperative bladder spasms.
Henriksen
L O
LO
Department of Surgery, Ringsted Hospital, Denmark.
Petersen
F
F
Nielsen
K R
KR
Agger
P
P
D000283:Administration, Intravesical; D000368:Aged; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004629:Emepronium / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010919:Placebos; D011468:Prostatectomy / Q000009:adverse effects*; D000644:Quaternary Ammonium Compounds / Q000627:therapeutic use*; D013035:Spasm / Q000188:drug therapy*; D001743:Urinary Bladder / Q000187:drug effects*; D014546:Urinary Catheterization
D010919:Placebos; D000644:Quaternary Ammonium Compounds; D004629:Emepronium