title: Leukemia relapse in host cells 5 years after bone marrow transplantation for acute non-lymphocytic leukemia in first complete remission.
abstract: A case of leukemia relapse in a 15-year-old girl occurring 5 years after successful allogeneic bone marrow transplantation for acute non-lymphocytic leukemia is reported. Laboratory findings demonstrated that this relapse was in host cells and had the same phenotype as the original leukemia. Incomplete lymphoid chimerism after bone marrow transplantation might have resulted in an inappropriate graft-versus-leukemia effect.
authors.affiliation: Department of Pediatrics, University Hospital, Leiden, The Netherlands.
authors.forename: E T
authors.initials: ET
authors.lastname: van't Veer-Korthof
authors.forename: M H
authors.initials: MH
authors.lastname: van Weel-Sipman
authors.forename: K
authors.initials: K
authors.lastname: Hählen
authors.forename: A H
authors.initials: AH
authors.lastname: Heurkens
authors.forename: J M
authors.initials: JM
authors.lastname: Vossen
mesh_terms: D000293:Adolescent; D016026:Bone Marrow Transplantation; D005260:Female; D005819:Genetic Markers; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics / Q000601:surgery*; D012008:Recurrence; D012074:Remission Induction; D013997:Time Factors; D014184:Transplantation, Homologous
chemical_list: D005819:Genetic Markers