title: Regional citrate anticoagulation for hemodialysis following cardiovascular surgery.
abstract: Coronary artery revascularization and cardiac valve replacement have been performed with increasing frequency over the past decade in patients maintained on chronic hemodialysis. Hemodialysis is frequently required shortly after surgery for treatment of hyperkalemia or volume overload. Use of low-dose or regional heparinization for hemodialysis may cause bleeding in patients who have recently undergone open-heart surgery. We performed 16 hemodialyses using regional citrate anticoagulation in 4 maintenance dialysis patients who had recently undergone cardiothoracic surgery. Systemic anticoagulation did not occur during any of the initial procedures, and in each patient a decrease in sanguineous chest tube drainage was observed during the initial postoperative dialysis.
authors.affiliation: Department of Medicine, University of Kansas Medical Center, Kansas City.
authors.forename: J W
authors.initials: JW
authors.lastname: Lohr
authors.forename: S
authors.initials: S
authors.lastname: Slusher
authors.forename: D A
authors.initials: DA
authors.lastname: Diederich
mesh_terms: D000368:Aged; D002951:Citrates / Q000008:administration & dosage*; D003327:Coronary Disease / Q000601:surgery; D006349:Heart Valve Diseases / Q000601:surgery; D006350:Heart Valve Prosthesis; D006470:Hemorrhage / Q000517:prevention & control; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications; D008297:Male; D008875:Middle Aged; D009204:Myocardial Revascularization; D006435:Renal Dialysis
chemical_list: D002951:Citrates