Three new 7-keto sterols from the Mediterranean sponge Clathrina clathrus.
The CHCl3 extract of the Mediterranean sponge Clathrina clathrus was shown to contain three new sterols: (22 E)-3 beta-hydroxycholesta-5,8,22-trien-7-one (1), (22 E, 24 xi)-3 beta-hydroxy-24-methylcholesta-5,8,22-trien-7-one (2), and (22 E, 24 xi)-3 beta-hydroxy-24-ethylcholesta-5,8,22-trien-7-one (3), whose structures were elucidated on the basis of physico-chemical evidence.
Aiello
A
A
Dipartimento di Chimica delle Sostanze Naturali, Napoli, Italy.
Ciminiello
P
P
Fattorusso
E
E
Magno
S
S
D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D002782:Cholestenes / Q000302:isolation & purification*; D002783:Cholestenones / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011161:Porifera / Q000032:analysis*; D013055:Spectrophotometry, Infrared; D013261:Sterols / Q000302:isolation & purification*
D002782:Cholestenes; D002783:Cholestenones; D013261:Sterols; C060495:3-hydroxycholesta-5,8,22-trien-7-one; C060527:3-hydroxy-24-methylcholesta-5,8,22-trien-7-one; C060528:3-hydroxy-24-ethylcholesta-5,8,22-trien-7-one