[Effect of irradiation on the intracellular reception of glucocorticoids in tissues with various radiosensitivities].
The experiments with albino female rats showed that whole-body gamma-irradiation with a dose of 1 Gy caused various alterations in concentrations of cytoplasmic and nuclear glucocorticoid receptors depending on tissue radiosensitivity (liver, thymus) and postirradiation time-intervals (1, 3, 10, 30, and 60 days). There was also a change in the receptor affinity to glucocorticoids.
Konoplia
E F
EF
Luksha
G L
GL
Gavrilin
M A
MA
D000818:Animals; D003037:Cobalt Radioisotopes; D003907:Dexamethasone / Q000378:metabolism; D005260:Female; D005720:Gamma Rays; D008099:Liver / Q000528:radiation effects*; D011836:Radiation Tolerance; D051381:Rats; D011919:Rats, Inbred Strains; D011965:Receptors, Glucocorticoid / Q000378:metabolism / Q000528:radiation effects*; D013950:Thymus Gland / Q000528:radiation effects*; D013997:Time Factors; D014916:Whole-Body Irradiation
D003037:Cobalt Radioisotopes; D011965:Receptors, Glucocorticoid; D003907:Dexamethasone
Vliianie oblucheniia na vnutrikletochnuiu retseptsiiu glikokortikoidov v tkaniakh razlichnoĭ radiochuvstvitel'nosti.