title: [Defects in the prostaglandin system. VI. Acquired plasma factor defect].
abstract: A 44 year-old male was admitted to hospital in October 1984 presenting with enzymatic and electrocardiographic signs of posterior wall myocardial infarction. At this time 2 separate examinations revealed normal plasma factor activity. At the 1 year follow-up (November 1985) plasma factor activity was still present. However, in February 1987 for the first time, the patient's plasma failed to enhance PGI2 synthesis from vascular tissue in vitro. 3 further follow-up examinations within the next 6 weeks again revealed an acquired absence of plasma factor activity of unknown cause. No deterioration in clinical condition occurred. All relatives tested showed normal plasma factor activity.
authors.affiliation: Atheroskleroseforschungsgruppe (ASF), Wien.
authors.forename: H
authors.initials: H
authors.lastname: Sinzinger
authors.forename: P
authors.initials: P
authors.lastname: Fitscha
authors.forename: F
authors.initials: F
authors.lastname: Rauscha
authors.forename: J
authors.initials: J
authors.lastname: Kaliman
mesh_terms: D000328:Adult; D001685:Biological Factors / Q000172:deficiency*; D001798:Blood Proteins / Q000172:deficiency*; D011464:Epoprostenol / Q000096:biosynthesis; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000097:blood*; D010979:Platelet Function Tests
chemical_list: D001685:Biological Factors; D001798:Blood Proteins; C057670:prostacyclin synthesis stimulating plasma factor; D011464:Epoprostenol
vernacular_title: Defekte im Prostaglandinsystem. VI. Erworbener Plasmafaktordefekt.