[Current aspects of D-penicillamine and pregnancy].
Although the outcome of most pregnancies is normal under D-penicillamine a teratogenic effect of the drug is known from animal studies. A few cases of children with birth defects whose mothers received D-penicillamine during pregnancy are reported in the literature. Whether D-penicillamine therapy should be performed throughout pregnancy or whether it should be interrupted depends on the disease to be treated. While in patients with morbus Wilson, continuous treatment with D-penicillamine is justified, it is advisable to interrupt the therapy during pregnancy in patients with rheumatoid arthritis.
Miehle
W
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Klinik Wendelstein der BfA, Bad Aibling.
D000014:Abnormalities, Drug-Induced / Q000209:etiology; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D003555:Cystinuria / Q000188:drug therapy*; D005260:Female; D006527:Hepatolenticular Degeneration / Q000188:drug therapy*; D006801:Humans; D007231:Infant, Newborn; D010396:Penicillamine / Q000009:adverse effects* / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D012307:Risk Factors
D010396:Penicillamine
Aktuelles zu D-Penicillamin und Schwangerschaft.