Colon cancer: medical therapy.
Fluorouracil is the major chemotherapy agent currently available for colon cancer. It is utilized alone or in combination in a variety of schedules, though the optimal schedule has not yet been identified. In addition to the use for metastatic disease, fluorouracil also is useful for adjuvant treatment or in combination with radiation therapy for treatment of locoregional disease.
Poplin
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E
Division of Hematology and Oncology, Wayne State University, Detroit, Michigan.
Baker
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L
D003110:Colonic Neoplasms / Q000188:drug therapy*; D005472:Fluorouracil / Q000627:therapeutic use*; D006801:Humans; D007376:Interleukin-2 / Q000627:therapeutic use; D011743:Pyrimidines / Q000627:therapeutic use
D007376:Interleukin-2; D011743:Pyrimidines; C029269:5-fluoropyrimidine; D005472:Fluorouracil