[Initial antibacterial prophylaxis after bone marrow allograft. Pilot study with systemic vancomycin].
In 22 consecutive patients treated by allogenic bone marrow transplantation, the authors report their experience in complete gastrointestinal decontamination and prophylactic systemic vancomycin. Neither septicemia from the low digestive tract nor with Gram positive is noticed. A child developed septicemia with Capnocytophaga ochracea, resistant to vancomycin. There is no infectious death in this study and no significative toxicity is reported.
Rubie
H
H
Médecine Infantile B, Centre Hospitalier Universitaire Toulouse-Purpan, France.
Attal
M
M
Lemozy
J
J
Massip
P
P
Huguet
F
F
Pris
J
J
Robert
A
A
Régnier
C
C
D000293:Adolescent; D000328:Adult; D016026:Bone Marrow Transplantation; D002206:Capnocytophaga; D002648:Child; D002675:Child, Preschool; D006801:Humans; D008875:Middle Aged; D010865:Pilot Projects; D011183:Postoperative Complications / Q000517:prevention & control*; D011292:Premedication; D018805:Sepsis / Q000517:prevention & control*; D014184:Transplantation, Homologous; D014640:Vancomycin / Q000627:therapeutic use*
D014640:Vancomycin
Prophylaxie antibactérienne initiale après allogreffe de moelle osseuse. Etude pilote de vancomycine systémique.