title: [Gonadal and gonadotropic function of late middle-aged men and women with sequelae of ischemic stroke].
abstract: In a comparative study the authors determined peripheral blood concentrations of immunoreactive testosterone, estradiol, LH, FSH, and prolactin in 32 males and 21 females, aged 60-74 years, with consequences of ischemic stroke, and in clinically normal elderly subjects. A control group was composed of healthy young people aged 20 to 35 years. It was found that in males and females with a history of stroke secretory insufficiency of the gonads and changes in the gonadotropic function of the pituitary expressed in a relative redistribution of gonadotropin fractions were significantly more pronounced than in normal age-matched subjects. The patients of both sexes exhibited a considerable elevation of blood prolactin levels. Hyperprolactinemia may either follow stroke since the latter impairs the hypothalamic regulation of prolactin secretion or precede it contributing to the development of a metabolic background conducive to the development of cerebral atherosclerosis.
mesh_terms: D000368:Aged; D002545:Brain Ischemia / Q000503:physiopathology*; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008875:Middle Aged; D010053:Ovary / Q000503:physiopathology*; D010903:Pituitary Gland, Anterior / Q000503:physiopathology*; D011388:Prolactin / Q000097:blood; D013737:Testis / Q000503:physiopathology*; D013739:Testosterone / Q000097:blood
chemical_list: D013739:Testosterone; D004958:Estradiol; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
vernacular_title: Gonadnaia i gonadotropnaia funktsiia u pozhilykh muzhchin i zhenshchin s posledstviiami ishemicheskogo insul'ta.