title: [Various ways of standardizing and unifying biological methods of determining the activity of antibiotics].
abstract: It was shown possible to use nutrient media containing only salt components and agar-agar for determination of biological activity of tetracyclines (tetracycline, morphocycline, oxytetracycline and chlortetracycline), erythromycin and oleandomycin. A uniform nutrient medium containing ammonium chloride, trisubstituted sodium citrate, disubstituted sodium phosphate and agar-agar was developed. Glucose is added to this medium simultaneously with the test microbe, B. subtilis ATCC 6633. The medium of the above composition provided readily reproducible results.
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects / Q000254:growth & development*; D003470:Culture Media; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests / Q000592:standards
chemical_list: D000900:Anti-Bacterial Agents; D003470:Culture Media
vernacular_title: Nekotorye puti standartizatsii i unifikatsii biologicheskikh metodov opredeleniia aktivnosti antibiotikov.