Antitumor activity of Lactobacillus casei (LC 9018) against experimental mouse bladder tumor (MBT-2).
The purpose of this paper is to investigate the inhibitory effect of Lactobacillus casei (LC 9018) on the growth of transplantable murine bladder tumor. Lactobacillus casei, viable and/or heat-killed bacteria, either in oral or intravenous administration, produced a significant inhibitory effect on the tumor growth and much less pulmonary metastasis.
D000818:Animals; D001428:Bacterial Vaccines / Q000494:pharmacology*; D002295:Carcinoma, Transitional Cell / Q000473:pathology / Q000628:therapy*; D002478:Cells, Cultured; D005260:Female; D006801:Humans; D007780:Lacticaseibacillus casei / Q000276:immunology*; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary / Q000628:therapy; D051379:Mice; D008809:Mice, Inbred C3H; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000628:therapy*
D001428:Bacterial Vaccines