title: [Combined treatment of irradiation and 8 MHz radiofrequency hyperthermia with chemoembolization in advanced renal tumor].
abstract: A combined treatment of irradiation and 8 MHz radiofrequency hyperthermia after chemoembolization, using 20 mg of microencapsulated mitomycin C (MMC.mc), was undertaken in a patient with an advanced left renal tumor. The patient, a 70-year-old man, noticed a gross hematuria in February, 1984. CT showed a left renal tumor, 88 X 70 mm in size. Histological examination revealed clear cell carcinoma of the left kidney. The tumor was unresectable because of an invasion into the surrounding tissues. Chemoembolization was performed before the combined treatment of irradiation and hyperthermia. He received 23.2 Gy of irradiation and 10 sessions of hyperthermia. Intratumoral temperature reached 42.6 degrees C during the heating. After treatment, there was a tumor regression rate of 58%, as well as pain relief, and an improvement in his appetite loss. He died 8 months after this treatment. An autopsy specimen revealed bionecrotic tumor cells among the prominent necrotic and fibrotic tissues.
mesh_terms: D000368:Aged; D002292:Carcinoma, Renal Cell / Q000532:radiotherapy / Q000628:therapy*; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D007680:Kidney Neoplasms / Q000532:radiotherapy / Q000628:therapy*; D008207:Lymphatic Metastasis; D008297:Male; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage*; D011879:Radiotherapy Dosage
chemical_list: D008937:Mitomycins; D016685:Mitomycin