Asthma and rhinitis after exposure to glutaraldehyde in endoscopy units.
Four nurses working in endoscopy units complained of respiratory symptoms on exposure to alkaline glutaraldehyde used as a disinfectant for fibre-optic endoscopes. A provocation test was positive in two of these patients. This is the first report to use provocation testing to confirm a relation between exposure to alkaline glutaraldehyde and respiratory disease.
D000328:Adult; D000403:Airway Resistance; D000447:Aldehydes / Q000009:adverse effects*; D001249:Asthma / Q000139:chemically induced* / Q000503:physiopathology; D004202:Disinfectants / Q000009:adverse effects; D019723:Endoscopes; D004724:Endoscopy / Q000009:adverse effects*; D005260:Female; D005541:Forced Expiratory Volume; D005976:Glutaral / Q000009:adverse effects*; D006801:Humans; D012220:Rhinitis / Q000139:chemically induced* / Q000503:physiopathology
D000447:Aldehydes; D004202:Disinfectants; D005976:Glutaral