title: [Comparative evaluation of the efficacy of nitrosorbide and nitroglycerin in acute myocardial infarct patients].
abstract: Intravenous isosorbide dinitrate and nitroglycerin administered within early hours of myocardial infarction have a marked antianginal effect, stabilize the size of necrotic focus and promptly control acute left-ventricular insufficiency. Unlike nitroglycerin, isosorbide dinitrate has a more lasting action and does not affect heart rate and arterial blood pressure. It can therefore be used more extensively in patients with acute myocardial infarction.
mesh_terms: D000208:Acute Disease; D000787:Angina Pectoris / Q000188:drug therapy; D001145:Arrhythmias, Cardiac / Q000517:prevention & control; D004418:Dyspnea, Paroxysmal / Q000517:prevention & control; D004562:Electrocardiography; D005260:Female; D006333:Heart Failure / Q000517:prevention & control; D006801:Humans; D007548:Isosorbide Dinitrate / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D005996:Nitroglycerin / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D005996:Nitroglycerin; D007548:Isosorbide Dinitrate
vernacular_title: Sravnitel'naia otsenka éffektivnosti nitrosorbida i nitroglitserina u bol'nykh ostrym infarktom miokarda.