[Kinetics of germ killing and damage to selected bacterial enzymes by thermal and chemical influences. III. Damage to enzymes from Bacillus subtilis by disinfectants compared to bacterial count reduction].
In the present paper a trial is reported to determine the efficacy of disinfectants by common bacteriological means as well as by biochemical methods. The results are compared, and they reveal a remarkable correlation (r = -0.9476) between the velocity constants of disinfection (1/kw) and the lg 1/Ki(app). The Ki(app)-value is the inhibition constant for the competitive inhibition of the creatine kinase reaction from Bacillus subtilis by disinfectants. The practical impacts are discussed.
D001412:Bacillus subtilis / Q000201:enzymology* / Q000254:growth & development; D003402:Creatine Kinase / Q000037:antagonists & inhibitors*; D004202:Disinfectants / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D007700:Kinetics; D012044:Regression Analysis
D004202:Disinfectants; D004791:Enzyme Inhibitors; D003402:Creatine Kinase
Zur Kinetik der Keimtötung und der Schädigung ausgewählter bakterieller Enzyme durch thermische und chemische Einwirkungen. III. Mitteilung: Die Schädigung von Enzymen aus Bacillus subtilis durch Desinfektionsmittel im Vergleich zur Keimzahlreduktion.