title: Chemoprophylaxis in clean-contaminated surgery.
abstract: Prophylaxis should be restricted to operations for which its benefit has been established. These are mainly operations in which a viscus colonized by bacteria is opened and in which bacterial contamination is unavoidable. The most important principle is to ensure adequate blood levels of antibiotic at the time of surgery. The choice of antibiotic should be based on knowledge of bacteria likely to cause infection.
mesh_terms: D000284:Administration, Oral; D000287:Administration, Topical; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001662:Biliary Tract Surgical Procedures; D003106:Colon / Q000601:surgery; D013505:Digestive System Surgical Procedures; D004334:Drug Administration Schedule; D006801:Humans; D007267:Injections; D011292:Premedication; D013530:Surgical Wound Infection / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents