title: [Arteriosclerosis and chelate therapy].
abstract: Based on a case history the therapeutic value of an iv-chelate therapy in arteriosclerosis is discussed. Ethylenediaminetetraacetate (EDTA) is used as a standard regime in the treatment of poisoning with heavy metals. The usefulness of EDTA in arteriosclerosis is doubtful: some authors suppose, that Ca-deposits are removed from arteriosclerotic lesions. This concept has not yet been proven by in-vivo experiments. Severe side effects such as hypocalcemia may cause the death of a patient under treatment. Therefore no real indications exist for treatment of arteriosclerosis with EDTA.
mesh_terms: D000368:Aged; D001161:Arteriosclerosis / Q000188:drug therapy*; D001929:Brain Edema / Q000139:chemically induced; D002544:Cerebral Infarction / Q000139:chemically induced*; D003324:Coronary Artery Disease / Q000188:drug therapy*; D004492:Edetic Acid / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006996:Hypocalcemia / Q000139:chemically induced; D002546:Ischemic Attack, Transient / Q000188:drug therapy*
chemical_list: D004492:Edetic Acid
vernacular_title: Arteriosklerose und Chelattherapie.