An attempt to study the case fatality rate in Schistosoma japonicum infection in the Philippines.
As a sequence to a cross-sectional study on the clinical gradient of the disease by Pesigan et al., (1965) a follow-up of the subjects in that study was made after 12 years. Of the 135 untreated cases followed up, 23 (17.04%) died from various causes of which 12 (8.89%) had signs and symptoms attributable to schistosomiasis as the immediate cause or one of the main causes of death. This occurred in 1 to 11 years with an average of 5 years, which corresponds roughly to 1.78% of the infected cases per year. This is considered a conservative estimate because in the other deaths due to other diseases, schistosomiasis is a contributory cause. A diminishing severity of the disease was observed among the surviving patients which could imply that they must have developed some degree of immunity to the disease.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D005243:Feces / Q000469:parasitology; D005500:Follow-Up Studies; D006529:Hepatomegaly / Q000209:etiology; D006801:Humans; D008875:Middle Aged; D010679:Philippines; D012554:Schistosomiasis japonica / Q000401:mortality*; D013163:Splenomegaly / Q000209:etiology