title: Neonatal advantage of epidural anesthesia in elective and emergency cesarean sections: a report of 531 cases.
abstract: In 147 elective and 384 non-elective cesarean sections, the need for neonatal respiratory assistance at birth was significantly greater for babies born under general anesthesia compared to epidural anesthesia, and the differences could not be explained by differences in pre-operative risk factors. For 114 babies on whom blood gas data were gathered prospectively, a greater proportion born under general anesthesia were acidemic and hypercarbic. Our results complement a growing body of retrospective and clinical data suggesting that epidural anesthesia is preferable to general in all but a few cesarean sections. Ideally, this suggestion should be tested in a randomized clinical trial.
mesh_terms: D000137:Acid-Base Imbalance / Q000209:etiology*; D000138:Acidosis / Q000209:etiology; D000767:Anesthesia, Epidural / Q000009:adverse effects*; D000768:Anesthesia, General / Q000009:adverse effects; D000773:Anesthesia, Obstetrical / Q000009:adverse effects*; D002245:Carbon Dioxide / Q000097:blood; D002585:Cesarean Section; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006935:Hypercapnia / Q000209:etiology; D000860:Hypoxia / Q000209:etiology*; D007231:Infant, Newborn; D010100:Oxygen / Q000097:blood; D011247:Pregnancy; D011446:Prospective Studies
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen