Immunological comparison of heat-shock proteins and alpha-crystallin.
It has been shown using ELISA and affinity chromatography, that extracts from heat-shocked Drosophila melanogaster larvae and cultured cells react with monoclonal antibodies raised against bovine alpha-crystallin. It is suggested that this cross-reactivity is associated with the region of the sequence corresponding to residues 98-108 of the bovine alpha A-crystallin chain. This region may be important for the functions of both alpha-crystallin and the heat-shock proteins.
D000595:Amino Acid Sequence; D000937:Antigen-Antibody Reactions; D003429:Cross Reactions; D003459:Crystallins / Q000276:immunology / Q000502:physiology*; D004331:Drosophila melanogaster; D006360:Heat-Shock Proteins / Q000276:immunology / Q000502:physiology*; D007158:Immunologic Techniques; D007814:Larva
D003459:Crystallins; D006360:Heat-Shock Proteins