title: Effect of acidification of the duodenal contents on splanchnic circulation and metabolism.
abstract: Portal vein (PF) and superior mesenteric artery blood flows (SMAF), arterial and portal venous oxygen concentrations were measured in dogs before and after duodenal introduction of 3 ml/kg 0.1 mol HCl. The duodenal acidification increased PF by 30% and SMAF by 35%. The change of mesenteric oxygen utilisation, from 0.80 +/- 0.10 to 0.81 ml/kg was not significant. It is concluded that the circulatory changes after acidification of the duodenal contents are not secondary to a metabolic effect.
mesh_terms: D000818:Animals; D002245:Carbon Dioxide / Q000097:blood; D004285:Dogs; D004386:Duodenum / Q000502:physiology; D005260:Female; D005766:Gastrointestinal Contents; D006863:Hydrogen-Ion Concentration; D007422:Intestines / Q000098:blood supply / Q000502:physiology*; D008297:Male; D008638:Mesenteric Arteries / Q000502:physiology; D010100:Oxygen / Q000097:blood; D010101:Oxygen Consumption; D011169:Portal Vein / Q000502:physiology; D013152:Splanchnic Circulation
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen