title: Relationship between sporulation and synthesis of mycobacillin and dipicolinic acid under condition of catabolite repression in Bacillus subtilis.
abstract: Sporulation was repressed in the parent strain by various carbon sources whereas glucose-resistant mutants were resistant to them but not to glycerol 2-phosphate. Both mycobacillin and dipicolinic acid synthesis were repressed in the parent by some of the compounds tested, viz. glucose, pyruvate and glycerol 2-phosphate. However, these syntheses in the glucose-resistant mutants were not repressed by glucose and pyruvate but were repressed by glycerol 2-phosphate. The possible interrelationship between sporulation, dipicolinic acid and mycobacillin synthesis is discussed in light of these findings.
mesh_terms: D000935:Antifungal Agents / Q000096:biosynthesis*; D001412:Bacillus subtilis / Q000378:metabolism / Q000502:physiology*; D005947:Glucose / Q000378:metabolism; D005994:Glycerophosphates / Q000378:metabolism; D009158:Mycobacillin / Q000096:biosynthesis*; D010848:Picolinic Acids / Q000096:biosynthesis*; D011773:Pyruvates / Q000378:metabolism; D013171:Spores, Bacterial
chemical_list: D000935:Antifungal Agents; D005994:Glycerophosphates; D010848:Picolinic Acids; D011773:Pyruvates; D009158:Mycobacillin; D005947:Glucose; C004860:dipicolinic acid