Results of the rec-assay of nitropyrenes in the Bacillus subtilis test system.
The rec-assay of the nitropyrenes in Bacillus subtilis was performed. All nitropyrene derivatives were positive in this system. Especially, 3 isomers of 1,3-, 1,6- and 1,8-dinitropyrene and 4-nitropyrene were found to possess strong DNA-damaging capacities at extremely low concentrations.
D001412:Bacillus subtilis / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development; D008826:Microbial Sensitivity Tests; D009152:Mutagenicity Tests; D009153:Mutagens / Q000494:pharmacology*; D009154:Mutation; D009574:Nitro Compounds / Q000494:pharmacology; D011721:Pyrenes / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D009153:Mutagens; D009574:Nitro Compounds; D011721:Pyrenes