Proteases of the pathogenic neisseriae: possible role in infection.
Proteolytic enzymes are produced by animal as well as human pathogens. Several micro-organisms including Neisseriae produce IgA1 specific proteases. This protease specifically hydrolyses IgA1 protein. IgA1-specific protease(s) synthesized by Neisseria species are briefly reviewed with particular reference to their role in infection.
D000626:Aminopeptidases / Q000378:metabolism; D001215:Asparaginase / Q000378:metabolism; D004492:Edetic Acid / Q000494:pharmacology; D010450:Endopeptidases / Q000378:metabolism; D005260:Female; D006069:Gonorrhea / Q000201:enzymology / Q000382:microbiology; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology / Q000378:metabolism; D007071:Immunoglobulin A, Secretory / Q000276:immunology / Q000378:metabolism; D008297:Male; D008585:Meningitis, Meningococcal / Q000201:enzymology / Q000382:microbiology; D008589:Meningococcal Infections / Q000201:enzymology / Q000382:microbiology; D009344:Neisseria gonorrhoeae / Q000201:enzymology*; D009345:Neisseria meningitidis / Q000201:enzymology*; D010447:Peptide Hydrolases / Q000378:metabolism*; D012697:Serine Endopeptidases; D013379:Substrate Specificity
D007070:Immunoglobulin A; D007071:Immunoglobulin A, Secretory; D004492:Edetic Acid; D010450:Endopeptidases; D010447:Peptide Hydrolases; D000626:Aminopeptidases; D012697:Serine Endopeptidases; C021433:IgA-specific serine endopeptidase; D001215:Asparaginase