Effect of thyrotropin-releasing hormone on vestibular compensation in primates.
Continual administration of thyrotropin-releasing hormone (TRH) (250 micrograms/kg/day) for 14 days using an osmotic mini-pump in unilateral labyrinthectomized squirrel monkeys induced accelerated vestibular compensation. Decrease in total gait deviation counts and reduction of slow-phase eye velocity of spontaneous nystagmus were significantly faster in the TRH-treated group as compared with the control group.
D000818:Animals; D007758:Ear, Inner / Q000502:physiology; D005260:Female; D005684:Gait; D008297:Male; D009760:Nystagmus, Physiologic / Q000187:drug effects; D004856:Postural Balance; D012453:Saimiri; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology*; D014722:Vestibule, Labyrinth / Q000187:drug effects* / Q000502:physiology
D013973:Thyrotropin-Releasing Hormone