title: [Lactotropic and thyrotropic functions of the hypophysis in polycystic ovary syndrome].
abstract: An increase in the prolactin basal level was detected in 8 out of 50 patients with ovarian polycystosis. A test with TRH and a simultaneous determination of the levels of prolactin, TTH, T3, T4 were used in 25 patients, of them a hyperergic reaction of prolactin to TRH was detected in 5. A correlation analysis of function of the thyroid was performed. Positive correlation between the levels of prolactin and TTH in patients with hyperprolactinemia and between a maximum increment in percentage to the initial level of TTH and prolactin in patients with a hyperergic reaction of prolactin to TRH was revealed. A conclusion was made of the common nature of disorder in the mechanisms of regulation of prolactin and thyroid function in patients with ovarian polycystosis.
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D006966:Hyperprolactinemia / Q000209:etiology*; D007031:Hypothalamus / Q000378:metabolism; D010903:Pituitary Gland, Anterior / Q000378:metabolism*; D011085:Polycystic Ovary Syndrome / Q000503:physiopathology*; D011388:Prolactin / Q000378:metabolism*; D013961:Thyroid Gland / Q000378:metabolism; D013972:Thyrotropin / Q000378:metabolism* / Q000502:physiology; D013973:Thyrotropin-Releasing Hormone / Q000502:physiology; D013974:Thyroxine / Q000378:metabolism; D014284:Triiodothyronine / Q000378:metabolism
chemical_list: D014284:Triiodothyronine; D013973:Thyrotropin-Releasing Hormone; D011388:Prolactin; D013972:Thyrotropin; D013974:Thyroxine
vernacular_title: Laktotropnaia i tireotropnaia funktsii gipofiza pri polikistoze iaichnikov.