title: M4HS2, a new human T-cell line for the efficient generation of human T-cell hybrids.
abstract: We have developed and characterised a variant of the human T-cell tumour, MOLT-4F, which is resistant to both 8-azaguanine and 6-thioguanine. This new cell line, M4HS2, is suitable for the efficient production of lymphokine-secreting human T-cell hybrids and is available for distribution.
mesh_terms: D000328:Adult; D000945:Antigens, Differentiation, T-Lymphocyte; D000954:Antigens, Surface / Q000032:analysis; D001375:Azaguanine / Q000494:pharmacology; D002460:Cell Line; D003470:Culture Media; D006801:Humans; D006822:Hybrid Cells / Q000166:cytology* / Q000187:drug effects; D007621:Karyotyping; D008222:Lymphokines / Q000378:metabolism; D013601:T-Lymphocytes / Q000166:cytology* / Q000187:drug effects / Q000378:metabolism; D013866:Thioguanine / Q000494:pharmacology
chemical_list: D000945:Antigens, Differentiation, T-Lymphocyte; D000954:Antigens, Surface; D003470:Culture Media; D008222:Lymphokines; D013866:Thioguanine; D001375:Azaguanine