title: [Isolation of the proteolytic complex from industrial waste waters from streptomycin production].
abstract: Dynamics of industrial biosynthesis of polyenzymic Streptomyces griseus system proteases and changes in their activities are studied in the process of streptomycin production. The method to isolate protease preparations is developed with optimization of production cycles of the stabilization, vacuum-concentration, ballast protein salting-out and lyophilization stages. The preparation is low toxic, retains 98% of the proteolytic activity at the temperature of 60 degrees C, 30 and 80%--under the effect of EDTA and urea, the activity maximum is at pH 7.0-8.0. The production technique of the preparation is estimated for its economic efficiency.
mesh_terms: D007218:Industrial Microbiology; D007220:Industrial Waste / Q000032:analysis*; D009097:Multienzyme Complexes / Q000302:isolation & purification*; D010447:Peptide Hydrolases / Q000302:isolation & purification*; D013305:Streptomyces griseus / Q000201:enzymology*
chemical_list: D007220:Industrial Waste; D009097:Multienzyme Complexes; D010447:Peptide Hydrolases
vernacular_title: Vydelenie proteoliticheskogo kompleksa iz tekhnologicheskikh stochnykh vod proizvodstva streptomitsina.