Metastatic calcification in the stomach demonstrated by a bone scan in Bence Jones lambda myeloma.
A 53-year-old male with Bence Jones lambda myeloma developed hypercalcemia and acute renal failure (calcium 14.4 mg/dl, BUN 40 mg/dl, creatinine 3.0 mg/dl) after initial response to chemotherapy. A 99mTc-MDP bone scan revealed unusual isotope accumulation in the left hypochondrium. Extensive calcium deposition was confirmed in the gastric mucosa in the postmortem examination. Detection of gastric calcification by a bone scan is very rare. Only two cases of gastric calcification visualized on bone scans can be found in the literature, one with multiple myeloma) and one in Hodgkin's disease).
D001536:Bence Jones Protein / Q000652:urine; D001853:Bone Marrow / Q000473:pathology; D002114:Calcinosis / Q000000981:diagnostic imaging* / Q000209:etiology; D006801:Humans; D007146:Immunoglobulin lambda-Chains / Q000652:urine; D007668:Kidney / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D011877:Radionuclide Imaging; D013272:Stomach Diseases / Q000000981:diagnostic imaging* / Q000209:etiology
D007146:Immunoglobulin lambda-Chains; D001536:Bence Jones Protein