title: Fresh gas flow requirements using the ADE anaesthetic system during late pregnancy.
abstract: Thirty-two pregnant patients at term undergoing elective Caesarean section were ventilated with a non-co-axial ADE anaesthetic system (E mode) supplied with fresh gas flows (FGF) of either 70 or 100 ml kg-1 min-1, on a random basis. Ventilation with an FGF of 70 ml kg-1 min-1 produced mean PaCO2 and PE' CO2 values of 6.48 +/- 1.15 kPa and 6.41 +/- 0.76 kPa, respectively. Patients were thus hypercapnic, which contrasts with the normocapnia achieved using an FGF of 100 ml kg-1 min-1 via the ADE system (E mode) (PaCO2 5.07 +/- 0.7 kPa; PE' CO2 4.83 +/- 0.46 kPa) (mean values +/- SD). The latter FGF is therefore recommended for the pregnant patient at term when using a Mapleson E system such as the Humphrey ADE apparatus.
mesh_terms: D000293:Adolescent; D000328:Adult; D000769:Anesthesia, Inhalation; D000773:Anesthesia, Obstetrical; D002245:Carbon Dioxide / Q000097:blood / Q000502:physiology*; D005260:Female; D006801:Humans; D007385:Intermittent Positive-Pressure Ventilation; D010100:Oxygen / Q000008:administration & dosage; D010313:Partial Pressure; D011175:Positive-Pressure Respiration; D011247:Pregnancy / Q000502:physiology*; D011263:Pregnancy Trimester, Third
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen