title: Intravenous midazolam in oral surgery.
abstract: Intravenously administered midazolam (0.1 mg/kg) was compared with placebo in a randomized study in 50 patients undergoing oral surgical procedures under local anaesthesia. The results obtained from this study showed that midazolam when compared to placebo had slight cardiovascular and respiratory depressant effects, diminished anxiety and caused amnesia. It also provided better operating conditions and possibly stimulated appetite.
mesh_terms: D000293:Adolescent; D000328:Adult; D000766:Anesthesia, Dental; D001007:Anxiety / Q000517:prevention & control; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008568:Memory / Q000187:drug effects; D008874:Midazolam / Q000008:administration & dosage*; D008875:Middle Aged; D010919:Placebos; D011229:Preanesthetic Medication; D011897:Random Allocation; D014081:Tooth Extraction; D014095:Tooth, Impacted / Q000601:surgery*
chemical_list: D010919:Placebos; D008874:Midazolam