Peripheral lymphocyte subpopulations changes during labor.
Peripheral circulating E-rosette-forming cells subpopulations (high affinity and low affinity E--RFC) were studied in pregnant women. In prelabor the high affinity/low affinity E--RFC ratio was found to decrease as compared with the controls by the decrease of the high affinity E--RFC (mean +/- SD, 33.4 +/- 15.9%, p less than 0.01) and the increase of the low affinity E--RFC percentage (mean +/- SD, 37.0 +/- 11.8%, p less than 0.001). As compared with prelabor the low affinity E--RFC subpopulation decreased during normal labor (mean +/- SD, 14.1 +/- 6.2%, p less than 0.001) and not in abnormal labor. These changes might be implicated in the final "fetal allograft rejection" and are probably due to some serum factors in pregnancy.
D005260:Female; D005312:Fetal Blood / Q000276:immunology; D006801:Humans; D007743:Labor, Obstetric / Q000276:immunology*; D008214:Lymphocytes / Q000145:classification*; D007744:Obstetric Labor Complications / Q000276:immunology; D010298:Parity; D011247:Pregnancy; D012397:Rosette Formation