[Use of sheep erythrocytes and plasma for the determination of neuroparalytic substances in vitro].
A simple method of the determination of nerve-paralytic substances is presented, based on the use of ram erythrocytes and plasma with the determination of cholinesterase inhibition. Dichlorvos administered at the rate of 94.64 ng per litre induced 50% inhibition of acetylcholinesterase in the erythrocytes; administration of dichlorvos at the rate of 243.82 ng per litre caused a 50% inhibition of butyrylcholinesterase in the plasma.
D000110:Acetylcholinesterase / Q000097:blood*; D000818:Animals; D002091:Butyrylcholinesterase / Q000097:blood*; D002800:Cholinesterase Inhibitors; D002802:Cholinesterases / Q000097:blood*; D004006:Dichlorvos / Q000494:pharmacology; D009498:Neurotoxins / Q000032:analysis* / Q000494:pharmacology; D012756:Sheep / Q000097:blood*
D002800:Cholinesterase Inhibitors; D009498:Neurotoxins; D004006:Dichlorvos; D000110:Acetylcholinesterase; D002091:Butyrylcholinesterase; D002802:Cholinesterases
Vyuzitie baraních erytrocytov a plazmy na stanovenie nervovoparalytických látok in vitro.