title: Linkage between the porcine genes encoding immunoglobulin heavy-chain allotypes and some serum alpha-protease inhibitors: a conserved linkage in pig, mouse and human.
abstract: Linkage between the genes coding for immunoglobulin heavy-chain allotypes and some serum alpha-protease inhibitors was demonstrated in pigs by means of segregation data in families. A recombination frequency of about 8% was estimated. This represents evolutionary conservation of an autosomal linkage group as linkage between the homologous loci has previously been reported, in humans and in mice.
mesh_terms: D000818:Animals; D005075:Biological Evolution; D005796:Genes; D008040:Genetic Linkage; D006239:Haplotypes; D006801:Humans; D007126:Immunoglobulin Allotypes / Q000235:genetics*; D007143:Immunoglobulin Heavy Chains / Q000235:genetics*; D051379:Mice; D011480:Protease Inhibitors / Q000235:genetics*; D013045:Species Specificity; D013552:Swine / Q000235:genetics*
chemical_list: D007126:Immunoglobulin Allotypes; D007143:Immunoglobulin Heavy Chains; D011480:Protease Inhibitors