[Microangiopathic hemolytic anemia associated with gastric cancer].
A case of advanced gastric cancer associated with metastatic carcinomatosis of the bone marrow, microangiopathic hemolytic anemia (MAHA) and disseminated intravascular coagulation (DIC) was reported. A 71-year-old woman complained of lumbago and general fatigue. At the time of admission, besides anemia, jaundice and a tendency to bleeding, the laboratory data showed, hyperbilirubinemia, elevated FDP and hemolytic anemia with fragmented red cells. The bone marrow was infiltrated by carcinoma, and an upper GI series examination showed Borrmann II type gastric cancer on the greater curvature of the antrum. After remission of both MAHA and DIC by mitomycin C, neothramycin and FOY, the patient successfully underwent subtotal gastrectomy. However, she died of cerebral hemorrhage on the 96th postoperative day.
D000230:Adenocarcinoma / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D000368:Aged; D000743:Anemia, Hemolytic / Q000150:complications* / Q000188:drug therapy; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001570:Benzodiazepinones / Q000008:administration & dosage; D003131:Combined Modality Therapy; D005260:Female; D016670:Gabexate; D006146:Guanidines / Q000008:administration & dosage; D006801:Humans; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000601:surgery
D001570:Benzodiazepinones; D006146:Guanidines; D008937:Mitomycins; D016670:Gabexate; D016685:Mitomycin; C012453:neothramycins