title: [Urinary delta-aminolevulinic acid levels in dairy cows during lead loading from feed rations under normal conditions of rearing in the Western Slovakia Region].
abstract: The concentration of delta-amino levulinic acid (ALA) was determined in the urine of clinically healthy cows of 14 herds in the West-Slovakian region. The content of lead was determined at the same time in the components of feed rations. The ALA concentration values were converted to values per uniform specific weight of urine and per gram of secreted creatinine to match literary sources where the ALA concentration is given in these two quantities. The approximate intake of lead by the animal bodies in milligrams per head/day and per kg of live weight was calculated from lead content in feed rations. The average ALA concentration in the urine of dairy cows was 42.7 +/- 20.2 mu mol per 1 of urine (36.8 +/- 18.7 mu mol per g of creatinine), the average lead intake from feed being 0.157 mg per kg of live weight. The ALA concentrations in urine refer to animals given normal feeds with no lead contamination and as such can be considered as physiological values. Statistically significant correlations were recorded between ALA concentrations per litre of urine at the uniform specific weight of 1030 g per litre and the values converted per gram of secreted creatinine (r = 0.789). The upper biological tolerance limit of ALA concentration in urine (105.0 mu mol per litre) was determined by mathematico-statistical methods. Values above this limit could be indicative of an increased lead stress of the cows' bodies.
mesh_terms: D000622:Aminolevulinic Acid / Q000652:urine*; D000821:Animal Feed; D000818:Animals; D002417:Cattle / Q000652:urine*; D002418:Cattle Diseases / Q000652:urine*; D005260:Female; D007854:Lead / Q000008:administration & dosage; D007855:Lead Poisoning / Q000652:urine / Q000662:veterinary*; D007982:Levulinic Acids / Q000652:urine*
chemical_list: D007982:Levulinic Acids; D007854:Lead; D000622:Aminolevulinic Acid
vernacular_title: Koncentrácie kyseliny delta-aminolevulovej v moci dojníc pri zátazi olovom z kŕmnych dávok v bezných podmienkach chovov Západoslovenského kraja.