[Effect of thermal treatment on the structure and biological properties of tuberculin].
The effect of heat treatment used in the course of tuberculin production by Mycobacteria tuberculosis cells on the structure and biological activity of tuberculin was studied. Methods of preparative and analytical gel-filtration were used. The largest quantity of the biologically active component was obtained after 2-hour heat treatment of the mycobacteria culture.
D001431:Bacteriological Techniques; D002850:Chromatography, Gel; D006358:Hot Temperature; D009163:Mycobacterium bovis / Q000032:analysis; D009169:Mycobacterium tuberculosis / Q000032:analysis; D014373:Tuberculin / Q000302:isolation & purification*
D014373:Tuberculin
Vliianie termicheskoĭ obrabotki na strukturu i biologicheskuiu aktivnost' tuberkulina.