title: Nasal secretions of Neisseria lactamica carriers have an inhibitory effect on Neisseria meningitidis attachment to human oroepithelial cells.
abstract: Nasal secretions of volunteers colonized by N. lactamica impaired the attachment of N. lactamica and of meningococci of groups A and B to oroepithelial cells. Bacterial adherence was found to be mediated by nonpiliated adhesins with antigen(s) which probably are shared by the strains tested. Although a strong attachment-inhibiting activity arises in their nasal secretions, volunteers remained colonized by N. lactamica. This evidence suggest that the eradication of Neisseria carriage is a multifactorial event.
mesh_terms: D000328:Adult; D001422:Bacterial Adhesion; D004847:Epithelial Cells; D006801:Humans; D009297:Nasal Mucosa / Q000378:metabolism*; D009305:Nasopharynx / Q000166:cytology / Q000382:microbiology*; D009343:Neisseria / Q000502:physiology*; D009345:Neisseria meningitidis / Q000502:physiology*