Sequential calcium and phosphorus balance studies in preterm infants.
Forty-six infant boys less than 1500 g at birth and less than 32 weeks gestation were fed enterally from birth until day 47. Cohorts were given milk formula varying in calcium and phosphorus content: group A, calcium 45 mg/dL, phosphorus 33 mg/dL; group B, calcium 85 mg/dL, phosphorus 33 mg/dL; group C, calcium 125 mg/dL, phosphorus 33 mg/dL; group D, calcium 125 mg/dL, phosphorus 50 mg/dL; and group E, calcium 125 mg/dL, phosphorus 64 mg/dL. Three-day balance studies were begun at days 10, 20, 30, and 40. Calcium net absorption and retention were influenced by postnatal age and calcium intake. Calcium retention best approached intrauterine accretion rates in group C. Phosphorus was well absorbed irrespective of the calcium content of the milk. Phosphorus retention increased with increments in the calcium content of the milk. Increasing the phosphorus content of the milk (groups D and E) resulted in no overall change in calcium absorption and retention but some increments in phosphorus retention.
D001724:Birth Weight; D002118:Calcium / Q000097:blood / Q000378:metabolism* / Q000652:urine; D004750:Enteral Nutrition; D005243:Feces / Q000032:analysis; D005865:Gestational Age; D006801:Humans; D007225:Infant Food / Q000032:analysis; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D010758:Phosphorus / Q000097:blood / Q000378:metabolism* / Q000652:urine; D013223:Statistics as Topic
D010758:Phosphorus; D002118:Calcium