Plasmapheresis in a patient with scleromyxedema.
We describe a patient with progressive scleromyxedema who failed to respond to previously described treatment modalities. A trial of plasmapheresis was initiated, but after an initial promising response, his disease continued to progress. The skin involvement appeared to progress even more rapidly after the plasmapheresis was discontinued.
D000328:Adult; D003131:Combined Modality Therapy; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism; D008297:Male; D009077:Mucins / Q000378:metabolism*; D009083:Mucopolysaccharidoses / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D010956:Plasmapheresis; D012871:Skin Diseases / Q000378:metabolism / Q000473:pathology / Q000628:therapy*
D007074:Immunoglobulin G; D009077:Mucins