title: [Comparison of the effect and serum level of mepivacaine HCL and mepivacaine CO2 in axillary brachial plexus anesthesia].
abstract: The latency period and spread of axillary plexus block using 40 ml mepivacaine carbonate (1% solution) or mepivacaine hydrochloride was studied in thirty patients scheduled for surgery of the hand-forearm region. The sensory block of the nervus axillaris, musculocutaneus, radialis, medianus, ulnaris and cutaneus brachii medialis was recorded using the pin prick test every 4 min after injection and the motor block was assessed by testing the strength of the corresponding muscles. The only significant difference between the two local anaesthetic solutions was a few more frequent and faster anaesthesia of the nervus musculocutaneus after 16, 20 and 24 min. A comparison between the serum levels of the first five patients of each group showed a faster increase and a higher level after the injection of carbonated mepivacaine. Carbonated mepivacaine doesn't have any practical advantage for axillary plexus block.
mesh_terms: D000765:Anesthesia, Conduction; D001917:Brachial Plexus / Q000187:drug effects*; D002245:Carbon Dioxide; D006225:Hand / Q000294:innervation / Q000601:surgery*; D006801:Humans; D008619:Mepivacaine / Q000097:blood; D009046:Motor Neurons / Q000187:drug effects; D009619:Nociceptors / Q000187:drug effects; D010525:Peripheral Nerves / Q000187:drug effects; D011897:Random Allocation; D012677:Sensation / Q000187:drug effects
chemical_list: D002245:Carbon Dioxide; D008619:Mepivacaine
vernacular_title: Wirkungsvergleich und Serumspiegel von Mepivacain-HCl und Mepivacain-CO2 bei axillärer Plexus brachialis-Anaesthesie.