Antiphospholipid antibodies: an elderly statesman Dons new garments.
Recent findings have renewed interest in antiphospholipid antibodies. The association of lupus anticoagulant with thrombosis, fetal loss, thrombocytopenia and possibly a Coombs' positive test is among these findings. A method to detect anticardiolipin antibodies and the association of these antibodies with the same clinical disorders as the lupus anticoagulant suggest a relationship between these 2 antibodies.
D000974:Antibodies, Antinuclear / Q000032:analysis; D001323:Autoantibodies / Q000032:analysis*; D001779:Blood Coagulation Factors / Q000032:analysis / Q000276:immunology; D002308:Cardiolipins / Q000276:immunology; D004247:DNA / Q000276:immunology; D005260:Female; D005313:Fetal Death; D006801:Humans; D007231:Infant, Newborn; D016682:Lupus Coagulation Inhibitor; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D010743:Phospholipids / Q000276:immunology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology; D012306:Risk; D013921:Thrombocytopenia / Q000276:immunology; D013927:Thrombosis / Q000276:immunology
D000974:Antibodies, Antinuclear; D001323:Autoantibodies; D001779:Blood Coagulation Factors; D002308:Cardiolipins; D016682:Lupus Coagulation Inhibitor; D010743:Phospholipids; D004247:DNA