title: Hypoproteinemic alkalosis.
abstract: Hypoproteinemia by itself causes a nonrespiratory ("metabolic") alkalosis. On the average, a decrease in plasma albumin concentration of 1 g/dl produces an increase in "standard" bicarbonate of 3.4 mM/liter, and an apparent base excess of +3.7 meq/liter; it also reduces the value of the normal anion gap by about 3 meq/liter. Concentration of plasma protein should be measured as part of the analysis of acid-base status. Interpretation of acid-base data requires special consideration in "primary hypoproteinemic alkalosis."
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000471:Alkalosis / Q000097:blood / Q000209:etiology*; D001639:Bicarbonates / Q000097:blood; D001798:Blood Proteins / Q000032:analysis; D002245:Carbon Dioxide / Q000097:blood; D002712:Chlorides / Q000097:blood; D005260:Female; D006801:Humans; D007019:Hypoproteinemia / Q000150:complications*; D008875:Middle Aged; D012709:Serum Albumin / Q000032:analysis; D012964:Sodium / Q000097:blood
chemical_list: D001639:Bicarbonates; D001798:Blood Proteins; D002712:Chlorides; D012709:Serum Albumin; D002245:Carbon Dioxide; D012964:Sodium