title: [Importance of T-lymphocytes in antibody production in experimental typhus infection].
abstract: The study of antibody production in cotton rats infected with Rickettsia prowazekii B and TB has revealed that R. prowazekii antigens, inducing the production of antibodies determined in the complement fixation, indirect hemolysis, and passive hemagglutination tests, are T-independent. The study of the nonspecific reactivity of T-lymphocytes in cotton rats infected with R. prowazekii TB has indicated that in case of the prolonged persistence of the infective agent in the animals no secondary immune deficiency develops.
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D000921:Antibody-Producing Cells / Q000276:immunology*; D000942:Antigens, Bacterial / Q000276:immunology; D000955:Antigens, T-Independent / Q000276:immunology; D003411:Arvicolinae; D007114:Immunization; D008297:Male; D012283:Rickettsia prowazekii / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D013934:Thymectomy; D013997:Time Factors; D014438:Typhus, Epidemic Louse-Borne / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D000955:Antigens, T-Independent
vernacular_title: Znachenie T-limfotsitov v produktsii antitel pri éksperimental'noĭ sypnotifoznoĭ infektsii.