title: Effect of ciprofloxacin on carrier rate of Neisseria meningitidis in army recruits in Finland.
abstract: The efficacy of ciprofloxacin in eradicating pharyngeal colonization of Neisseria meningitidis was studied among army recruits in Finland. Ciprofloxacin (250 mg) or placebo was given twice a day for 2 days to 118 meningococcal carriers. Meningococcal carriage was eradicated in 96% of subjects given ciprofloxacin and in 13% of those given placebos.
mesh_terms: D002353:Carrier State / Q000188:drug therapy* / Q000382:microbiology; D002939:Ciprofloxacin / Q000627:therapeutic use*; D005387:Finland; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008889:Military Personnel; D009345:Neisseria meningitidis / Q000187:drug effects; D010614:Pharynx / Q000382:microbiology
chemical_list: D002939:Ciprofloxacin