Osteonecrosis, fractures, and protrusio acetabuli secondary to x-irradiation therapy for prostatic carcinoma.
Two years after pelvic irradiation for prostatic cancer, bilateral protrusio acetabuli and collapse of the right femoral head requiring prosthetic arthroplasty developed in a 73-year-old man with chronic rheumatoid arthritis. There was no evidence of metastases. Histologic evaluation showed empty lacunae in the bone but no evidence of obliterative endarteritis. Osteonecrosis and pathologic fractures constitute a rare complication of high voltage irradiation.
D000077:Acetabulum / Q000000981:diagnostic imaging / Q000293:injuries / Q000528:radiation effects; D000230:Adenocarcinoma / Q000532:radiotherapy*; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications; D005271:Femur Head Necrosis / Q000000981:diagnostic imaging / Q000209:etiology; D005598:Fractures, Spontaneous / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D008297:Male; D010025:Osteoradionecrosis / Q000000981:diagnostic imaging / Q000209:etiology*; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D011630:Pubic Bone / Q000293:injuries; D011832:Radiation Injuries / Q000209:etiology*; D011882:Radiotherapy, High-Energy / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed