Malignant angioendotheliomatosis proliferans. Report of an autopsied case studied with immunoperoxidase.
We report the autopsy findings in a case of malignant angioendotheliomatosis proliferans. Neoplastic cells stained positively for leukocyte common antigen, factor VII-related antigen, and IgG by the indirect peroxidase-antiperoxidase technique. The authors speculate that malignant angioendotheliomatosis proliferans represents a distinctive type of neoplasm that appears either to exhibit bidirectional lymphoid and endothelial differentiation or to consist of an heterogeneous population of cells.
D000368:Aged; D000369:Aged, 80 and over; D000911:Antibodies, Monoclonal; D000941:Antigens / Q000378:metabolism; D005169:Factor VIII / Q000276:immunology / Q000378:metabolism; D006390:Hemangioendothelioma / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008854:Microscopy, Electron; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*; D014841:von Willebrand Factor
D000911:Antibodies, Monoclonal; D000941:Antigens; D014841:von Willebrand Factor; D005169:Factor VIII