Severe intrahepatic cholestasis and rapidly progressive renal failure in a patient with immunocyte-related amyloidosis.
A woman developed severe cholestatic jaundice and progressive renal failure secondary to amyloid deposition. The amyloid protein was of AL type, consisting of IgG-related kappa chains. This form of amyloidosis is classified as immunocyte-related, not associated with myeloma.
D000686:Amyloidosis / Q000150:complications* / Q000276:immunology / Q000473:pathology; D001853:Bone Marrow / Q000473:pathology; D002780:Cholestasis, Intrahepatic / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007074:Immunoglobulin G / Q000032:analysis; D007147:Immunoglobulin Light Chains / Q000032:analysis; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D007676:Kidney Failure, Chronic / Q000209:etiology*; D008875:Middle Aged; D010950:Plasma Cells / Q000473:pathology; D000685:Serum Amyloid A Protein / Q000032:analysis
D007074:Immunoglobulin G; D007147:Immunoglobulin Light Chains; D007145:Immunoglobulin kappa-Chains; D000685:Serum Amyloid A Protein