The influence of seizure type and medication on psychiatric symptoms in epileptic patients.
The influence of type of seizure and medication on psychological disability was assessed using the Standard Psychiatric Interview in matched epileptic patients. In comparison to patients with idiopathic tonic-clonic seizures, those with temporal lobe epilepsy complained of more irritability and impaired concentration, and were rated as more depressed and slowed up. Compared to patients on phenytoin, those on carbamazepine complained of more sleep disturbance and were more likely to be taking an hypnotic.
D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use*; D001288:Attention; D002220:Carbamazepine / Q000097:blood; D004831:Epilepsies, Myoclonic / Q000523:psychology; D004827:Epilepsy / Q000188:drug therapy / Q000523:psychology*; D004833:Epilepsy, Temporal Lobe / Q000523:psychology; D005260:Female; D006801:Humans; D007508:Irritable Mood; D008297:Male; D010672:Phenytoin / Q000097:blood; D012893:Sleep Wake Disorders / Q000150:complications; D012923:Social Class
D000927:Anticonvulsants; D002220:Carbamazepine; D010672:Phenytoin