title: A bifunctional ligand for Pd(II).
abstract: A bifunctional ligand, 6-(5-carboxyl pentyl)-5,7 dioxo-1,4,8, 11-tetraazaundecane, has been shown to produce a neutral, inert complex with Pd(II). The complex is formed in high yield and is stable over a wide pH range. It can be conjugated to proteins through the carboxylic acid side arm using a carbodiimide coupling reagent and may be useful for labeling antibodies or other large molecules.
mesh_terms: D001372:Aza Compounds / Q000138:chemical synthesis; D002614:Chelating Agents; D004492:Edetic Acid / Q000494:pharmacology; D006801:Humans; D007074:Immunoglobulin G; D007202:Indicators and Reagents; D007700:Kinetics; D008024:Ligands; D009942:Organometallic Compounds / Q000138:chemical synthesis; D010165:Palladium; D011485:Protein Binding; D012709:Serum Albumin / Q000378:metabolism
chemical_list: D001372:Aza Compounds; D002614:Chelating Agents; D007074:Immunoglobulin G; D007202:Indicators and Reagents; D008024:Ligands; D009942:Organometallic Compounds; D012709:Serum Albumin; C051152:6-(5-carboxylpentyl)-5,7-dioxo-1,4,8,11-tetraazaundecane 109 Pd(II); D010165:Palladium; D004492:Edetic Acid