Adult T-ALL related to transitional cortical-medullary thymocytes with surface markers of the CD4 subset.
This report describes a case of adult T-acute lymphoblastic leukemia. Leukemic blast cells of this patient displayed a rare intermediate cortical-medullary phenotype (E-sheep+, OKT3-, OKT6+, OKT9+, OKT10+, OKT11+) with features of the CD4 subset (OKT4+, OKT8-, Fc mu+, Fc gamma-).
D000328:Adult; D000911:Antibodies, Monoclonal / Q000032:analysis; D006801:Humans; D007945:Leukemia, Lymphoid / Q000097:blood*; D008297:Male; D010641:Phenotype; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000032:analysis*
D000911:Antibodies, Monoclonal