title: Comparison of the susceptibility of Brucella abortus isolates obtained before and after cows were treated with oxytetracycline and streptomycin.
abstract: Eight isolates of Brucella abortus were obtained from cows before and after they were treated with oxytetracycline and streptomycin. The susceptibility to these antibiotics was determined by broth-dilution minimal inhibitory and minimal lethal concentrations. Differences were not found in the minimal lethal concentrations of oxytetracycline or streptomycin in isolates obtained from cows before and after they were treated. This indicates that treatment failures in the cows were not the result of development of resistance to the antibiotics by B abortus.
mesh_terms: D000818:Animals; D002003:Brucella abortus / Q000187:drug effects*; D002007:Brucellosis, Bovine / Q000188:drug therapy* / Q000382:microbiology; D002417:Cattle; D004352:Drug Resistance, Microbial; D005260:Female; D008826:Microbial Sensitivity Tests; D010118:Oxytetracycline / Q000494:pharmacology* / Q000627:therapeutic use; D013307:Streptomycin / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D010118:Oxytetracycline; D013307:Streptomycin