title: Analytical methodology for organophosphorus pesticides used in Canada.
abstract: An overview of analytical methodology for the determination of organophosphate pesticides residues in foods is presented. Sample extraction is carried out with acetone followed by a dichloromethane-hexane partition. The organic extract is purified by automated gel permeation chromatography and analysed by capillary gas chromatography with flame photometric or thermionic detection. Confirmation can be carried out by a variety of chemical derivatization techniques including hydrolysis followed by reaction of the phosphate or phenol moiety, direct alkylation or trifluoracetylation. Thin-layer chromatography with enzyme inhibition detection can be used as a rapid screening technique or to confirm results obtained by gas chromatography. Liquid chromatography has not been used much for the determination of organophosphorus compounds in foods.
mesh_terms: D002170:Canada; D002849:Chromatography, Gas; D002853:Chromatography, Liquid; D002855:Chromatography, Thin Layer; D005506:Food Contamination; D005779:Immunodiffusion; D007306:Insecticides / Q000032:analysis*; D009943:Organophosphorus Compounds
chemical_list: D007306:Insecticides; D009943:Organophosphorus Compounds