Post-surgical deterioration of renal function in primary hyperoxaluria.
Primary hyperoxaluria leading to calcium oxalate urinary stones and renal deposits occurs rarely in adults. We report three cases in whom end-stage renal failure was precipitated by urological surgery. In contrast, in one case renal stones were destroyed by extracorporeal shock-wave lithotripsy and renal function was not significantly altered. This emphasises the need for early diagnosis. This may not be easy in adult patients: urolithiasis may not be severe, radiological nephrocalcinosis may be lacking, and renal failure may develop late in life.
D000328:Adult; D005260:Female; D006801:Humans; D006959:Hyperoxaluria / Q000601:surgery*; D006960:Hyperoxaluria, Primary / Q000601:surgery*; D007669:Kidney Calculi / Q000601:surgery*; D007676:Kidney Failure, Chronic / Q000209:etiology*; D008297:Male; D011183:Postoperative Complications / Q000209:etiology*