Biochemical monitoring of children with neuroblastoma.
In this article, a short review is given of the biochemical aspects of diagnosis, estimation of prognosis and follow-up of neuroblastoma in children. The importance of determination of patterns of DOPA-metabolites, rather than single metabolite assay, is stressed and illustrated by patient cases. Also the relevance of urinary cystathionine and beta-amino-isobutyric acid is indicated.
D000621:Aminoisobutyric Acids / Q000652:urine; D002648:Child; D003540:Cystathionine / Q000652:urine; D004295:Dihydroxyphenylalanine / Q000378:metabolism; D006719:Homovanillic Acid / Q000031:analogs & derivatives / Q000652:urine; D006801:Humans; D007980:Levodopa / Q000378:metabolism; D008991:Monitoring, Physiologic; D009447:Neuroblastoma / Q000652:urine*; D009638:Norepinephrine / Q000378:metabolism; D011379:Prognosis
D000621:Aminoisobutyric Acids; C013331:vanilglycolic acid; D003540:Cystathionine; D007980:Levodopa; D004295:Dihydroxyphenylalanine; C033435:3-aminoisobutyric acid; D009638:Norepinephrine; D006719:Homovanillic Acid