Transient lupus anticoagulant and fansidar therapy.
A case of the Stevens-Johnson syndrome following Fansidar therapy is reported in which a marked feature was the presence of a circulating anticoagulant of the lupus inhibitor type. Treatment with steroids resulted in complete recovery and disappearance of the anticoagulant.
D000328:Adult; D000962:Antimalarials / Q000009:adverse effects*; D001779:Blood Coagulation Factors / Q000037:antagonists & inhibitors* / Q000097:blood; D004338:Drug Combinations / Q000009:adverse effects; D006801:Humans; D016682:Lupus Coagulation Inhibitor; D008297:Male; D011739:Pyrimethamine / Q000009:adverse effects*; D013262:Stevens-Johnson Syndrome / Q000097:blood / Q000139:chemically induced*; D013413:Sulfadoxine / Q000009:adverse effects*; D013424:Sulfanilamides / Q000009:adverse effects*
D000962:Antimalarials; D001779:Blood Coagulation Factors; D004338:Drug Combinations; D016682:Lupus Coagulation Inhibitor; D013424:Sulfanilamides; C001205:fanasil, pyrimethamine drug combination; D013413:Sulfadoxine; D011739:Pyrimethamine