Influence of the primary anticoagulant on the recovery of factor VIII in cryoprecipitate.
The influence of anticoagulant on overall factor VIII-yield was measured by drawing blood from one donor simultaneously in three bags containing ACD, CPD and heparin, respectively. After parallel processing factor VIII:C and factor VIII:CAg were measured. It is concluded that, under the circumstances used in this experiment, CPD gives the highest yield of factor VIII.
D000225:Adenine / Q000494:pharmacology; D000925:Anticoagulants / Q000494:pharmacology*; D011232:Chemical Precipitation / Q000379:methods*; D002951:Citrates / Q000494:pharmacology; D019343:Citric Acid; D005169:Factor VIII / Q000302:isolation & purification*; D005615:Freezing; D005947:Glucose / Q000031:analogs & derivatives / Q000494:pharmacology; D006493:Heparin / Q000494:pharmacology; D006801:Humans; D008297:Male; D010710:Phosphates / Q000494:pharmacology
D000925:Anticoagulants; C034876:CPDA solutions; D002951:Citrates; D010710:Phosphates; C002113:acid citrate dextrose; D019343:Citric Acid; D005169:Factor VIII; D006493:Heparin; D005947:Glucose; D000225:Adenine