Mixed hyperplastic and neoplastic polyp of the colon. An immunohistological study.
A small colonic polyp which was composed of equal parts of hyperplastic and adenomatous tissue sharing a common basement membrane, displayed a paradoxical distribution of immunohistological markers: In contrast with the neoplastic component, the hyperplastic tissue lacked signs of functional maturity (IgA, secretory component) and displayed markers associated with carcinoma (carcinoembryonic antigen, peanut-agglutinin binding).
D000236:Adenoma / Q000276:immunology / Q000648:ultrastructure*; D000368:Aged; D000951:Antigens, Neoplasm / Q000276:immunology; D002272:Carcinoembryonic Antigen / Q000032:analysis; D003111:Colonic Polyps / Q000276:immunology / Q000648:ultrastructure*; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D007124:Immunoenzyme Techniques; D007071:Immunoglobulin A, Secretory / Q000032:analysis; D008297:Male
D000951:Antigens, Neoplasm; D002272:Carcinoembryonic Antigen; D007071:Immunoglobulin A, Secretory