Dopachrome conversion and dopa oxidase activities in recessive yellow mice. Catalytic activities of extracts from pheomelanic and eumelanic tissues.
The dopa oxidase activity of tyrosinase and the dopachrome conversion activity of dopachrome oxidoreductase (dopachrome conversion factor) are reduced in skin or hair follicle extracts of pheomelanic mice compared with eumelanic mice. In this study, pheomelanic tissues are compared with eumelanic tissues of the same mice and found to be reduced in their DO and DC activities. Implications are discussed.
D000818:Animals; D004156:Catechol Oxidase / Q000235:genetics*; D005123:Eye / Q000201:enzymology*; D005796:Genes; D005808:Genes, Recessive; D045563:Indolequinones; D007211:Indoles / Q000378:metabolism*; D007700:Kinetics; D051379:Mice; D008810:Mice, Inbred C57BL; D008817:Mice, Mutant Strains; D014442:Monophenol Monooxygenase / Q000235:genetics* / Q000378:metabolism; D011809:Quinones / Q000378:metabolism*; D012867:Skin / Q000201:enzymology*
D045563:Indolequinones; D007211:Indoles; D011809:Quinones; C001123:dopachrome; D004156:Catechol Oxidase; D014442:Monophenol Monooxygenase