title: [Use of L-DOPA in the complex treatment of severe craniocerebral injuries].
abstract: The article is based on an analysis of the results of clinicobiochemical study of 15 patients with severe craniocerebral trauma (SCCT) whose intensive multiple-modality treatment included the use of L-DOPA. All the patients presented with direct traumatic lesions of the subcortical structures attended by diminished excretion of dopamine and DOPA. A favourable clinical effect was related to the use of DOPA which indicates that it is advisable that the drug be included into the combined therapy of severe injury to the brain attended by dysfunction of the subcortical formations.
mesh_terms: D000293:Adolescent; D000328:Adult; D001930:Brain Injuries / Q000188:drug therapy* / Q000652:urine; D002648:Child; D003131:Combined Modality Therapy; D004295:Dihydroxyphenylalanine / Q000652:urine; D004298:Dopamine / Q000652:urine; D004837:Epinephrine / Q000652:urine; D005500:Follow-Up Studies; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D008875:Middle Aged; D009638:Norepinephrine / Q000652:urine; D013577:Syndrome
chemical_list: D007980:Levodopa; D004295:Dihydroxyphenylalanine; D004298:Dopamine; D009638:Norepinephrine; D004837:Epinephrine
vernacular_title: Primenenie L-DOFA v kompleksnom lechenii tiazheloĭ cherepno-mozgovoĭ travmy.