title: Mechanisms of deoxyguanosine toxicity for human T and B lymphocytes.
mesh_terms: D001402:B-Lymphocytes / Q000187:drug effects*; D002453:Cell Cycle / Q000187:drug effects; D002454:Cell Differentiation / Q000187:drug effects; D002478:Cells, Cultured; D003841:Deoxycytidine / Q000494:pharmacology; D003848:Deoxyguanine Nucleotides / Q000378:metabolism; D003849:Deoxyguanosine / Q000633:toxicity*; D006151:Guanosine / Q000031:analogs & derivatives / Q000378:metabolism / Q000494:pharmacology; D006160:Guanosine Triphosphate / Q000378:metabolism; D006801:Humans; D019271:Hypoxanthine; D007041:Hypoxanthine Phosphoribosyltransferase / Q000378:metabolism; D007042:Hypoxanthines / Q000494:pharmacology; D066298:In Vitro Techniques; D008213:Lymphocyte Activation / Q000187:drug effects; D011683:Purine-Nucleoside Phosphorylase / Q000378:metabolism; D013601:T-Lymphocytes / Q000187:drug effects*
chemical_list: D003848:Deoxyguanine Nucleotides; D007042:Hypoxanthines; D003841:Deoxycytidine; D006151:Guanosine; D019271:Hypoxanthine; C032533:8-aminoguanosine; D006160:Guanosine Triphosphate; C029603:deoxyguanosine triphosphate; D011683:Purine-Nucleoside Phosphorylase; D007041:Hypoxanthine Phosphoribosyltransferase; D003849:Deoxyguanosine