title: Effect of metal ions on the antimicrobial activity of 5-sulphosalicylic acid.
abstract: Bis-(5-sulphosalicylato)-diaquo chelates of VO(II), Cu(II), Ni(II), Co(II), Fe(II) and Mn(II) exerted antifungal activities. The chelates have been characterised for elemental, thermal and infra-red spectral studies and were found to be more fungicidal than the chelating agent. The antifungal activity was found to be in the order: Cu(II) congruent to Ni(II) greater than Co(II) greater than Fe(II) greater than Mn(II) greater than VO(II).
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D001234:Aspergillus niger / Q000187:drug effects; D001557:Benzenesulfonates; D003035:Cobalt / Q000494:pharmacology; D003300:Copper / Q000494:pharmacology; D005658:Fungi / Q000187:drug effects*; D007502:Iron Chelating Agents / Q000494:pharmacology; D008345:Manganese / Q000494:pharmacology; D008670:Metals / Q000494:pharmacology*; D009090:Mucorales / Q000187:drug effects; D009532:Nickel / Q000494:pharmacology; D010408:Penicillium chrysogenum / Q000187:drug effects; D012233:Rhizopus / Q000187:drug effects; D012459:Salicylates / Q000494:pharmacology*; D013055:Spectrophotometry, Infrared; D013818:Thermogravimetry; D014639:Vanadium / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D001557:Benzenesulfonates; D007502:Iron Chelating Agents; D008670:Metals; D012459:Salicylates; D014639:Vanadium; D003035:Cobalt; D008345:Manganese; D003300:Copper; D009532:Nickel; C003366:sulfosalicylic acid