Bone marrow suppression after intravesical mitomycin C treatment.
Intravesical chemotherapy has been established as a modality for the treatment and prevention of superficial bladder tumors. However, the optimal time for instillation of chemotherapy following transurethral resection is still not clear. We report on a patient with a superficial bladder tumor treated immediately after transurethral resection with relatively high dose mitomycin C. Bone marrow failure developed within 2 weeks. A possible relationship is suggested.
D000368:Aged; D000741:Anemia, Aplastic / Q000139:chemically induced*; D005260:Female; D006801:Humans; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D011182:Postoperative Care; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy / Q000601:surgery
D008937:Mitomycins; D016685:Mitomycin