title: Monoamine oxidase in rat ovary during the estrous cycle. A histochemical study by a new coupled peroxidatic oxidation method.
abstract: A new coupled peroxidatic oxidation method for histochemical detection of monoamine oxidase (MAO) was applied to rat ovary. With this new method, fixed tissues could be used, and two forms of MAO could be identified by use of selective inhibitors. MAO activity was observed in the corpora lutea, interstitial gland cells, and blood vessels. In the corpora lutea, no activity was detected during the first estrous cycle, but strong activity was observed in the next two cycles. MAO in blood vessels showed characteristic changes of activity during the estrous cycle. The results suggest that MAO activity might possibly be involved in ovulation and progesterone metabolism in the ovary. Like other organs, rat ovary was found to contain two types of MAO; type A MAO was predominant in the corpora lutea. On the other hand, only one type of MAO, type B, was found in the blood vessels.
mesh_terms: D000818:Animals; D001808:Blood Vessels / Q000201:enzymology; D003010:Clorgyline / Q000494:pharmacology; D003338:Corpus Luteum / Q000201:enzymology; D004971:Estrus; D005260:Female; D006651:Histocytochemistry; D006735:Horseradish Peroxidase; D008995:Monoamine Oxidase / Q000378:metabolism*; D008996:Monoamine Oxidase Inhibitors; D010053:Ovary / Q000098:blood supply / Q000201:enzymology*; D010084:Oxidation-Reduction; D051381:Rats; D011919:Rats, Inbred Strains; D012642:Selegiline / Q000494:pharmacology
chemical_list: D008996:Monoamine Oxidase Inhibitors; D012642:Selegiline; D006735:Horseradish Peroxidase; D008995:Monoamine Oxidase; D003010:Clorgyline