title: Carbon dioxide inhalation therapy for anxiety: effectiveness due to increased prostacyclin and decreased thromboxane biosynthesis? Re-evaluation of a neglected technique.
abstract: CO2 inhalation has been used for many years in the treatment of various psychiatric and medical disorders and different rationales for its effect have been offered. Since it has been recently found that CO2 inhibits thromboxane biosynthesis and raises levels of prostacyclin, a new rationale for the effect of CO2 inhalation, based on its inhibition of thromboxane biosynthesis, is offered.
mesh_terms: D001007:Anxiety; D002245:Carbon Dioxide / Q000627:therapeutic use*; D011464:Epoprostenol / Q000096:biosynthesis*; D006801:Humans; D012138:Respiratory Therapy; D013931:Thromboxanes / Q000096:biosynthesis*
chemical_list: D013931:Thromboxanes; D002245:Carbon Dioxide; D011464:Epoprostenol