title: Histodifferentiation and ultrastructure of oral squamous cell carcinoma in HMT rats.
abstract: Seven oral squamous cell carcinomas developed in HMT rats were studied with light and electron microscopy. Two carcinomas in extra-oral sites were also described. Histodifferentiation of oral squamous cell carcinomas ranged from well-differentiated to poorly-differentiated, comparable to that of the same disease in humans. Ultrastructural features characteristic of human oral carcinomas were observed in the HMT rat carcinomas.
mesh_terms: D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000648:ultrastructure; D002471:Cell Transformation, Neoplastic / Q000473:pathology / Q000648:ultrastructure; D003937:Diagnosis, Differential; D005260:Female; D005833:Genital Neoplasms, Female / Q000473:pathology / Q000648:ultrastructure; D008297:Male; D009062:Mouth Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D009374:Neoplasms, Experimental / Q000473:pathology / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains; D012878:Skin Neoplasms / Q000473:pathology / Q000648:ultrastructure