title: The comparative in vitro activity of spiramycin and erythromycin against Norwegian bacterial isolates.
abstract: The in vitro activity of spiramycin and erythromycin has been determined by an agar diffusion method against relevant clinical isolates. Generally, erythromycin was more active than spiramycin on a weight-for-weight basis. Spiramycin showed only moderate activity against Haemophilus influenzae and Streptococcus pyogenes. Gonococci were sensitive in vitro to both agents. Many erythromycin-resistant staphylococci were sensitive to spiramycin.
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D004352:Drug Resistance, Microbial; D004917:Erythromycin / Q000494:pharmacology*; D006193:Haemophilus influenzae / Q000187:drug effects; D007933:Leucomycins / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D009344:Neisseria gonorrhoeae / Q000187:drug effects; D009664:Norway; D013210:Staphylococcus / Q000187:drug effects; D013297:Streptococcus pyogenes / Q000187:drug effects
chemical_list: D007933:Leucomycins; D004917:Erythromycin