[Influence of BCG in the control of humoral deficiency induced by mastocytoma p-815].
Viable BCG bacilli, in a lipid emulsion, inoculated intravenously, were capable of reverting the profound humoral immunosuppression induced in adult DBA/2 mice by the mastocytoma P-815. BCG increased not only the number of hemolytic plaque forming cells, but also the serum titers of hemagglutinating IgM antibodies. However, no blocking effect was detected on normal tumor progression.
D000818:Animals; D000917:Antibody Formation; D005260:Female; D006462:Hemolytic Plaque Technique; D007075:Immunoglobulin M / Q000378:metabolism*; D012515:Mast-Cell Sarcoma / Q000276:immunology*; D051379:Mice; D008811:Mice, Inbred DBA; D009163:Mycobacterium bovis / Q000276:immunology*
D007075:Immunoglobulin M
Influência do BCG no controle da imunodeficiência humoral induzida pelo mastocitoma P-815.