Chelating agents for the binding of metal ions to antibodies.
The development and applications of bifunctional chelating agents are reviewed, with emphasis on the preparation of radiolabeled monoclonal antibodies suitable for use in vivo. Major principles and practical aspects of the chemical procedures are outlined, and new results of interest for future work are described.
D000911:Antibodies, Monoclonal; D002614:Chelating Agents; D004492:Edetic Acid; D008670:Metals; D008958:Models, Molecular; D008968:Molecular Conformation; D004369:Pentetic Acid; D011485:Protein Binding
D000911:Antibodies, Monoclonal; D002614:Chelating Agents; D008670:Metals; D004369:Pentetic Acid; D004492:Edetic Acid