[Epilepsy with continuous discharges during slow-wave sleep. Treatment with clobazam].
The authors describe the case of a 12 years old boy suffering from an epilepsy with complex partial seizures evolving to a syndrome of epilepsy with continuous spikes-waves during sleep. A dramatic improvement follows clobazam introduction in the treatment. The originality of this case report and the possible mechanism of action of clobazam are discussed.
D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D001570:Benzodiazepinones / Q000627:therapeutic use*; D002220:Carbamazepine / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D000078306:Clobazam; D002998:Clonazepam / Q000627:therapeutic use; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis; D006801:Humans; D008297:Male; D012894:Sleep Stages / Q000502:physiology; D014635:Valproic Acid / Q000627:therapeutic use
D014151:Anti-Anxiety Agents; D001570:Benzodiazepinones; D001569:Benzodiazepines; D000078306:Clobazam; D002220:Carbamazepine; D002998:Clonazepam; D014635:Valproic Acid
Epilepsie avec décharges continues au cours du sommeil lent. Guérison sous clobazam.