[Mechanism of the contraceptive action of the triterpene glycosides from the rock jasmine Androsace septentrionalis L].
The sum of triterpene glycosides of Androsace septentrionalis L. (a plant of genus Primula) was shown to change the concentrations of lutropin and follitropin in the hypophysis and plasma and the ratio of these hormones in the blood plasma in the active phase of the cycle. This leads to the change of the ovarian hormonal activity in the direction of predominance of the estrogenic action and an increase of the uterine contractile activity that can be of certain significance in manifestation of the contraceptive effect.
D000818:Animals; D003271:Contraceptive Agents, Female / Q000494:pharmacology*; D004971:Estrus / Q000187:drug effects; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006027:Glycosides / Q000494:pharmacology*; D007986:Luteinizing Hormone / Q000097:blood; D051379:Mice; D010066:Ovum Transport / Q000187:drug effects; D010946:Plants, Medicinal; D011817:Rabbits; D051381:Rats; D014315:Triterpenes / Q000494:pharmacology*; D014590:Uterine Contraction / Q000187:drug effects
D003271:Contraceptive Agents, Female; D006027:Glycosides; D014315:Triterpenes; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
K mekhanizmu protivozachatochnogo deĭstviia triterpenovykh glikozidov prolomnika severnogo.