title: CO2 production after suxamethonium and diazepam.
abstract: The CO2-production and degree of relaxation after increasing doses of suxamethonium were measured in seven patients undergoing alloplastic surgery of the hip. The study indicates that the CO2-production rises following the injection of increasing doses of suxamethonium. Another group of patients received diazepam 0.1 mg kg-1 before the injection of suxamethonium 1 mg kg-1. CO2-production was significantly reduced compared to CO2 production when suxamethonium was not preceded by diazepam. It is suggested that diazepam in doses larger than 0.1 mg kg-1 might be effective in preventing fasciculations and postoperative muscle pains before the injection of suxamethonium in a dose of 0.5 mg kg-1.
mesh_terms: D000758:Anesthesia; D002245:Carbon Dioxide / Q000378:metabolism*; D003975:Diazepam; D006801:Humans; D013390:Succinylcholine
chemical_list: D002245:Carbon Dioxide; D013390:Succinylcholine; D003975:Diazepam