Haematuria and proteinuria in urinary schistosomiasis: response to therapy with praziquantel in Tanzanian children.
In order to assess the efficacy of praziquantel against Schistosoma haematobium and its effect on the morbidity indices, haematuria and proteinuria, a study was carried out using school receiving praziquantel at 40 mg/kg body weight. Twenty-four weeks after treatment, the percentage of cure was high and reached 100% among the 'light' and 'moderate' infection groups. In the 'heavy' infection group, a cure rate of 50% and a 69.3% egg reduction was observed. An overall cure rate of 94% was achieved at 24 weeks. Microhaematuria and proteinuria were reduced by 96.6% and 92.5%, respectively.
D002648:Child; D006417:Hematuria / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D011223:Praziquantel / Q000627:therapeutic use*; D011507:Proteinuria / Q000188:drug therapy* / Q000209:etiology; D011934:Reagent Strips; D012553:Schistosomiasis haematobia / Q000150:complications / Q000188:drug therapy*; D013636:Tanzania
D011934:Reagent Strips; D011223:Praziquantel