Treatment of urothelial carcinoma of the upper urinary tract following prostatocystectomy with mitomycin C instillation in the ileal loop.
We report a case of urothelial carcinoma of the upper urinary tract, which developed after prostatocystectomy. The patient was treated with instillations of 40 mg. mitomycin C in 40 ml. saline. No significant systemic side effects owing to perfusion of mitomycin C could be demonstrated. Complete remission of the small urothelial tumors occurred, as well as slight progression of a large pelvic carcinoma of the left kidney.
D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D003131:Combined Modality Therapy; D006801:Humans; D007082:Ileum / Q000601:surgery; D007680:Kidney Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008297:Male; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage / Q000627:therapeutic use*; D011468:Prostatectomy; D014516:Ureteral Neoplasms / Q000188:drug therapy* / Q000556:secondary; D014523:Urethral Neoplasms / Q000188:drug therapy* / Q000556:secondary; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy* / Q000601:surgery; D014547:Urinary Diversion
D008937:Mitomycins; D016685:Mitomycin