title: The pattern of early neuronal differentiation in Drosophila melanogaster.
abstract: Based on the staining of Drosophila embryos with neuron-specific monoclonal antibodies we describe the differentiation of the earliest neurons in the central nervous system. The metameric array undergoes a number of changes during development that distinguish several morphological units: metameres, neuromeres and ganglia. Neural landmarks in the CNS and the periphery are identified on the bases of their developmental history, axonal projection and segment specificity. A time sequence of differentiation starting in the posterior gnathal and anterior thoracic anlage has been found.
mesh_terms: D000367:Age Factors; D000818:Animals; D000911:Antibodies, Monoclonal; D002454:Cell Differentiation; D002490:Central Nervous System / Q000196:embryology; D004331:Drosophila melanogaster / Q000196:embryology*; D006110:Grasshoppers / Q000196:embryology; D006651:Histocytochemistry; D007158:Immunologic Techniques; D009474:Neurons / Q000196:embryology; D010525:Peripheral Nerves / Q000196:embryology
chemical_list: D000911:Antibodies, Monoclonal