[Measuring chemiluminescence in phagocytic granulocytes--simultaneously a parameter of their killing function?].
The results of the chemiluminescence activity determined in whole blood samples very often were used to compare the unspecific defense mechanism of polymorphonuclear granulocytes (PMN) against causative organisms to preoperative capable risk parameters in surgery. Our investigations try to compare the results of a bacteria-induced chemiluminescence with those we received from a standardized agar killing plate-test. It could be shown that there is no correlation between the used two test systems. Therefore it is not possible to conclude from the chemiluminescence results especially made out of whole blood samples to the potency of the defense mechanism of PMN granulocytes.
D003602:Cytotoxicity, Immunologic; D005455:Fluorescent Antibody Technique; D006801:Humans; D008163:Luminescent Measurements; D009504:Neutrophils / Q000276:immunology*; D010587:Phagocytosis; D011550:Pseudomonas aeruginosa / Q000276:immunology; D012306:Risk; D013530:Surgical Wound Infection / Q000276:immunology*; D015008:Yersinia enterocolitica / Q000276:immunology
Chemiluminescenzmessung phagocytierender Granulocyten--Gleichzeitig ein Parameter für ihre Killing-Funktion?