title: Estimation of arterial PCO2 during high frequency jet ventilation. Studies in the dog.
abstract: The arterial to end-tidal PCO2 difference (PaCO2-PE'CO2) was measured in five anaesthetized dogs during controlled ventilation at 0.25 Hz (15 b.p.m.) and during high frequency jet ventilation at 1, 3 and 5 Hz. Because of the slow response of the infra-red carbon dioxide analyser, satisfactory recordings of end-tidal carbon dioxide could not be obtained at frequencies greater than 1 Hz. The interruption of high frequency jet ventilation by conventional ventilation resulted in approximately equal arterial and end-tidal PCO2 values during the first breath, and restoration of the normal arterial to end-tidal PCO2 difference by the third breath. It is concluded that, when high frequency jet ventilation at 1, 3 or 5 Hz is interrupted with normal tidal volumes at low frequencies, the arterial PCO2 can be estimated from recordings of the end-tidal PCO2.
mesh_terms: D000818:Animals; D001158:Arteries; D002245:Carbon Dioxide / Q000097:blood* / Q000502:physiology; D004285:Dogs; D012121:Respiration, Artificial; D013990:Tidal Volume
chemical_list: D002245:Carbon Dioxide