Crystallization and preliminary X-ray investigation of a recombinant form of human gamma-interferon.
A genetically engineered human gamma-interferon has been crystallized from solutions of ammonium sulfate. The crystals are trigonal, space group R32, with hexagonal axes of a = 114.0(1) A and c = 314.9(2) A. The crystals are moderately stable to x-rays and diffract to 2.85-A resolution. Density measurements indicate that the crystallographic asymmetric volume contains four interferon molecules.
D003001:Cloning, Molecular; D003460:Crystallization; D006801:Humans; D007371:Interferon-gamma / Q000235:genetics / Q000302:isolation & purification; D014961:X-Ray Diffraction
D007371:Interferon-gamma