[Evaluation of the activity of various lysosomal enzymes in the cerebrospinal fluid and blood in cases of brain concussion].
The results of determinations of lysosomal enzymes: mannosidase, b-galactosidase and b-glucosidase, in the cerebrospinal fluid and blood are presented in 72 patients with severe brain trauma. The determinations were carried out at different times after the trauma. The study demonstrated a significantly lower level and in a smaller degree expressed variability of enzymes in the cerebrospinal fluid in relation to blood. It seems that the level of b-glucosidase in the cerebrospinal fluid depends on the level of this enzyme in the blood, while no such evident correlation was found for the remaining enzymes.
D000293:Adolescent; D000328:Adult; D001924:Brain Concussion / Q000201:enzymology*; D005260:Female; D005696:Galactosidases / Q000378:metabolism*; D005959:Glucosidases / Q000378:metabolism*; D006801:Humans; D008297:Male; D008361:Mannosidases / Q000097:blood / Q000134:cerebrospinal fluid / Q000378:metabolism*; D008875:Middle Aged; D001616:beta-Galactosidase / Q000097:blood / Q000134:cerebrospinal fluid / Q000378:metabolism*; D001617:beta-Glucosidase / Q000097:blood / Q000134:cerebrospinal fluid / Q000378:metabolism*
D005696:Galactosidases; D005959:Glucosidases; D008361:Mannosidases; D001617:beta-Glucosidase; D001616:beta-Galactosidase
Ocena aktywności niektórych enzymów lizosomalnych w płynie mózgowo-rdzeniowym i krwi w przypadkach stłuczenia mózgu.