Co-trimoxazole red cell aplasia in leukaemia.
A 4 year old boy with acute lymphoblastic leukaemia developed a pure red cell aplasia 13 months after entering remission and while on maintenance chemotherapy. Co-trimoxazole was also being administered for prophylaxis against Pneumocystis carinii infection. When co-trimoxazole was stopped the red cell aplasia resolved.
D000890:Anti-Infective Agents / Q000009:adverse effects*; D002675:Child, Preschool; D004338:Drug Combinations / Q000009:adverse effects; D006801:Humans; D007945:Leukemia, Lymphoid / Q000150:complications / Q000188:drug therapy; D008297:Male; D011020:Pneumonia, Pneumocystis / Q000517:prevention & control*; D012010:Red-Cell Aplasia, Pure / Q000139:chemically induced*; D013420:Sulfamethoxazole / Q000009:adverse effects*; D014295:Trimethoprim / Q000009:adverse effects*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
D000890:Anti-Infective Agents; D004338:Drug Combinations; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim; D013420:Sulfamethoxazole