title: [Effect of the type of nutrition and aflatoxin B1 on the structure of chromosomes].
abstract: Deficiency of the essential nutrients lysine, methionine, threonine and vitamins A, E, C significantly increases the mutagenic environment of somatic cells in growing Wag rats. Aflatoxin B1 produces a pronounced mutagenic effect on the cellular genetic apparatus; this effect is substantially modified due to the nutrition character: it is either intensified or inhibited. The results obtained suggest that the nutritional factors can de used for prevention and elimination of aflatoxin B1-induced mutations.
mesh_terms: D016604:Aflatoxin B1; D000348:Aflatoxins / Q000633:toxicity*; D000601:Amino Acids, Essential / Q000008:administration & dosage / Q000172:deficiency*; D000818:Animals; D002364:Caseins / Q000008:administration & dosage; D002869:Chromosome Aberrations / Q000187:drug effects*; D004044:Dietary Proteins / Q000008:administration & dosage; D008297:Male; D011488:Protein Deficiency / Q000235:genetics*; D051381:Rats
chemical_list: D000348:Aflatoxins; D000601:Amino Acids, Essential; D002364:Caseins; D004044:Dietary Proteins; D016604:Aflatoxin B1
vernacular_title: Vliianie kharaktera pitaniia i aflatoksina B1 na strukturnoe sostoianie khromosom.