title: Veterans Administration Cooperative Studies Project No. 147. Part I: A multidisciplinary, multicenter experimental design for the evaluation of alternative metal-ceramic alloys.
abstract: The factors necessary for a comprehensive multidisciplinary, multicenter clinical study have been incorporated into CSP No. 147. The experimental design provides the potential for multiple laboratory and clinical data comparisons of alternative alloys. The study incorporates clinical performance observations with dental and medical histories that permit many unique correlations. This potential demonstrates the comprehensiveness of the CSP No. 147 study design and its contributions to clinical dental research in the evaluation of restorative materials.
mesh_terms: D002858:Chromium Alloys; D002986:Clinical Trials as Topic; D003362:Cost-Benefit Analysis; D003442:Crowns / Q000009:adverse effects / Q000191:economics; D003776:Dental Porcelain; D003779:Denture Design / Q000191:economics; D003830:Denture, Partial, Fixed / Q000009:adverse effects / Q000191:economics; D005500:Follow-Up Studies; D006047:Gold Alloys; D006801:Humans; D010510:Periodontal Diseases / Q000175:diagnosis; D013499:Surface Properties
chemical_list: D002858:Chromium Alloys; D006047:Gold Alloys; D003776:Dental Porcelain