In vitro effects of Bacillus subtilis on the immune response.
The authors evaluated the in vitro effects of Bacillus subtilis on the following parameters of the immune response: mitogenic T cell proliferation (by PHA and OKT3) and mitogenic-induced lymphokine production (IL-2 and IFN-gamma). The spores of Bacillus subtilis did not influence the immune response, while its vegetative forms enhanced mitogenic-induced T cell proliferation. Both spores and vegetative forms did not modify lymphokine production.
D000328:Adult; D001412:Bacillus subtilis / Q000276:immunology*; D005260:Female; D006801:Humans; D007371:Interferon-gamma / Q000096:biosynthesis*; D007376:Interleukin-2 / Q000096:biosynthesis*; D008213:Lymphocyte Activation; D008297:Male; D008934:Mitogens / Q000494:pharmacology; D013171:Spores, Bacterial / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
D007376:Interleukin-2; D008934:Mitogens; D007371:Interferon-gamma