A case report of infantile striatal necrosis with an acute onset.
We report here an autopsy case, an 8-year-old boy diagnosed as having infantile striatal necrosis, characterized by a preceding febrile illness followed by acute encephalopathy with abrupt obtundation, seizures and dystonia, with remarkable improvement of the disturbed consciousness and intelligence after TRH-T therapy. These clinical symptoms were linked with bilateral necrosis of the striata on CT scanning. The presented case belonged to a newly described subgroup of the heredogenous disorders that produce necrosis of the putamina in children.
D001480:Basal Ganglia Diseases / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D002648:Child; D003342:Corpus Striatum; D005334:Fever / Q000150:complications; D006801:Humans; D008297:Male; D009336:Necrosis; D010612:Pharyngitis / Q000150:complications; D013973:Thyrotropin-Releasing Hormone / Q000627:therapeutic use
D013973:Thyrotropin-Releasing Hormone