title: [Surgery and the acquired inhibitor of factor VIII coagulant].
abstract: A case is reported of an 80 year old woman with old sarcoidosis and acquired factor VIIIc inhibitor undergoing orthopaedic surgery. This was successfully carried out after she had been given a total of 48,420 units of factor VIII concentrate: there were no haemorrhagic complications. The main pathological states in which acquired factor VIIIc inhibitor may be found are related: principal treatments available nowadays are discussed: immunosuppressors, human factor VIII, animal factor VIII, prothrombin complex concentrate, plasma exchange.
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005169:Factor VIII / Q000008:administration & dosage / Q000037:antagonists & inhibitors*; D005260:Female; D006467:Hemophilia A / Q000097:blood; D006620:Hip Fractures / Q000097:blood / Q000601:surgery; D006801:Humans; D011182:Postoperative Care; D011300:Preoperative Care; D013514:Surgical Procedures, Operative
chemical_list: D005169:Factor VIII
vernacular_title: Chirurgie et inhibiteur acquis du facteur VIII coagulant.