[Abnormal localization of proto-oncogene c-ets 1 in acute leukemia with translocation t(1: 11)(q21: q23)].
The chromosome localization of a 5.4 kb DNA genomic probe of proto-oncogene c-ets 1 has been analysed in an acute monocytic leukemia with t (1; 11) (q21; q23) translocation. The c-ets probe has been translocated onto the rearranged chromosome 1, suggesting the involvement of the proto-oncogene in leukemias with chromosome rearrangements at band 11 q23.
D002874:Chromosome Mapping; D002900:Chromosomes, Human, 1-3; D005260:Female; D006801:Humans; D007223:Infant; D007621:Karyotyping; D007948:Leukemia, Monocytic, Acute / Q000235:genetics*; D000090063:Proto-Oncogene Mas; D011519:Proto-Oncogenes; D014178:Translocation, Genetic
Localisation anormale du proto-oncogène c-ets 1 dans une leucémie aiguë avec translocation t(1; 11)(q21; q23).