Lithium treatment and cognitive changes in two mentally retarded patients.
Lithium carbonate was used to treat behavioral disorders in two mentally retarded patients. Although improvement was noted in the behaviors, cognitive performance, measured with the Peabody Picture Vocabulary Test, showed a decline, which was related to the serum lithium level. The implication of these changes is discussed.
D000184:Acting Out; D000328:Adult; D000374:Aggression / Q000187:drug effects*; D003071:Cognition / Q000187:drug effects*; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000523:psychology*; D007361:Intelligence Tests; D008094:Lithium / Q000097:blood / Q000494:pharmacology / Q000627:therapeutic use*; D016651:Lithium Carbonate; D008297:Male; D008418:Masturbation / Q000523:psychology
D016651:Lithium Carbonate; D008094:Lithium