Primary lymph node plasmocytoma of IgD-class.
An extramedullary plasmocytoma in a right inguinal lymph node was observed in a 62-year-old woman. The tumor showed monoclonal proliferation of plasma cells which revealed highly positive stainings of both IgD and lambda light chain using the PAP-technique. Monoclonal IgD-lambda was also secreted in serum and urine. Clinical data, lymphography and bone biopsy showed a tumor spreading in the right inguinal, left iliacal and lumbar regions without systemic involvement of bone. In contrast to extramedullary plasmocytomas of other immunoglobulin classes the disease progressed rapidly and the patient died 8 months after the onset. The present case is the first reported IgD-plasmocytoma in lymph nodes.
D005260:Female; D006801:Humans; D007072:Immunoglobulin D; D007146:Immunoglobulin lambda-Chains; D008198:Lymph Nodes; D008875:Middle Aged; D010954:Plasmacytoma / Q000175:diagnosis / Q000276:immunology*
D007072:Immunoglobulin D; D007146:Immunoglobulin lambda-Chains