title: Low set ears (Lse), a new mutation of the house mouse.
abstract: A new dominant mutation, low set ears (Lse), in the mouse may be indicative of a mammalian branchial arch syndrome. This developmental anomaly of the external ear is accompanied by eye defects, retarded growth and shortened lifespan. The ear defect can be identified in 13-day embryos. Further studies will determine the effects of the Lse gene on other systems.
mesh_terms: D000818:Animals; D003433:Crosses, Genetic; D004423:Ear / Q000002:abnormalities* / Q000033:anatomy & histology / Q000196:embryology; D005124:Eye Abnormalities; D005260:Female; D008297:Male; D051379:Mice; D008817:Mice, Mutant Strains / Q000196:embryology*