title: [A biological method for the determination of mycotoxins--Tetrahymena pyriformis].
abstract: The toxic action of selected mycotoxins on a biological subject was tested in the protozoan Tetrahymena pyriformis. The following toxins were tested: toxin T-2 at doses from 1.52 micrograms to 100.0 mg per litre of medium, ochratoxin A at doses from 12.21 micrograms to 800.0 mg per litre of medium, and rubratoxin B at doses from 12.21 micrograms to 800.0 mg per litre of medium. In toxin T-2 the LD100 was found to be about 390.63 micrograms and LD50 about 48.83 micrograms per litre of medium. In ochratoxin A the LD100 was about 25.0 mg and LD50 about 3.13 mg per litre of medium. In rubratoxin B the LD100 was about 200.0 mg and LD50 about 25.0 mg per litre of medium.
mesh_terms: D001681:Biological Assay / Q000379:methods*; D007928:Lethal Dose 50; D009183:Mycotoxins / Q000032:analysis* / Q000633:toxicity; D009793:Ochratoxins / Q000032:analysis / Q000633:toxicity; D013605:T-2 Toxin / Q000032:analysis / Q000633:toxicity; D013769:Tetrahymena pyriformis / Q000187:drug effects*
chemical_list: D009183:Mycotoxins; D009793:Ochratoxins; C025589:ochratoxin A; D013605:T-2 Toxin
vernacular_title: Biologická metóda na stanovenie mykotoxínov--Tetrahymena pyriformis.