Periodic sharp complexes in herpes simplex virus encephalitis: survival in an elderly man.
For the electroencephalographer, focal temporal periodic complexes have been strongly associated with herpes simplex virus encephalitis (HSVE). The appearance and subsequent disappearance of these complexes has generally been held to herald a poor prognosis. This report involves an elderly man with HSVE who survived with no neurologic deficits despite the presence and later disappearance of periodic sharp complexes. This supports the view that the periodic complexes are more a function of the pathophysiologic changes caused by HSVE as opposed to a marker of tissue injury.
D000212:Acyclovir / Q000627:therapeutic use; D000368:Aged; D004569:Electroencephalography; D004660:Encephalitis / Q000175:diagnosis* / Q000188:drug therapy; D004828:Epilepsies, Partial / Q000175:diagnosis; D005071:Evoked Potentials / Q000187:drug effects; D006561:Herpes Simplex / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008297:Male
D000212:Acyclovir