title: Mutagenicity of nickel sulphate in Drosophila melanogaster.
abstract: Nickel sulphate was injected into Drosophila melanogaster males at different concentrations in order to test the chemical for the induction of SLRL and SCL in germ cells. Nickel sulphate induced SLRL at concentrations tested, with the peak of activity at premeiotic and postmeiotic stages. It failed to produce SCL except at the highest concentration tested, where induction of XO males was significant for the pooled data.
mesh_terms: D000818:Animals; D002872:Chromosome Deletion; D004331:Drosophila melanogaster / Q000187:drug effects*; D005260:Female; D005804:Genes, Lethal / Q000187:drug effects; D005808:Genes, Recessive / Q000187:drug effects; D008297:Male; D009152:Mutagenicity Tests; D009532:Nickel / Q000494:pharmacology*; D012729:Sex Chromosome Aberrations / Q000139:chemically induced
chemical_list: C029938:nickel sulfate; D009532:Nickel