Establishment and characterization of a monocytic cell line which expresses the interleukin-2 receptor.
A cell line, SCC-3, was established from the pleural fluid of a patient with non-Hodgkin's lymphoma. Interleukin-2 receptor (IL2-R) was found to be expressed on the cell surface by marker analysis, and morphological, cytochemical, and other marker analyses suggested a monocytic lineage. SCC-3 may be useful for studies on the role of IL2-R in monocytic cells.
D000328:Adult; D001943:Breast Neoplasms / Q000276:immunology; D002460:Cell Line; D002469:Cell Separation; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000276:immunology; D008854:Microscopy, Electron; D009000:Monocytes / Q000276:immunology* / Q000473:pathology / Q000648:ultrastructure; D010996:Pleural Effusion / Q000473:pathology; D011971:Receptors, Immunologic / Q000032:analysis*; D015375:Receptors, Interleukin-2
D011971:Receptors, Immunologic; D015375:Receptors, Interleukin-2