[Expression of interleukin 2 receptor and class II histocompatibility antigens on lymphocytes of the cerebrospinal fluid in patients with multiple sclerosis and other neurological diseases].
The presence of IL2 receptor and HLA class II antigens on mononuclear cells from both cerebrospinal fluid (CSF) and peripheral blood was examined in patients with multiple sclerosis (MS) and other neurological diseases. Cytofluorographic analysis of mononuclear cells was performed by means of indirect immunofluorescence on a flow cytometer using a linear scale. CSF as compared to blood was enriched in cells expressing IL2 receptor and HLA class II molecules both in MS patients and in other inflammatory diseases of the central nervous system. The site of activation of these cells remains however questionable.
D000328:Adult; D005260:Female; D005455:Fluorescent Antibody Technique; D006681:HLA-D Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid / Q000276:immunology*; D009422:Nervous System Diseases / Q000134:cerebrospinal fluid / Q000276:immunology; D011971:Receptors, Immunologic / Q000032:analysis*; D015375:Receptors, Interleukin-2; D013601:T-Lymphocytes / Q000032:analysis*
D006681:HLA-D Antigens; D011971:Receptors, Immunologic; D015375:Receptors, Interleukin-2
Expression du récepteur de l'interleukine 2 et des antigènes d'histocompatibilité de classe II sur les lymphocytes du liquide céphalorachidien chez des patients atteints de sclérose en plaques et d'autres maladies neurologiques.