Certain membrane-interacting amphiphiles inhibit aggregation and reverse shape change of rabbit platelets pre-activated with arachidonic acid through dissociation of cytoskeletal assembly.
D000470:Alkaloids / Q000494:pharmacology*; D000818:Animals; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000494:pharmacology*; D044182:Benzylisoquinolines; D001792:Blood Platelets / Q000166:cytology* / Q000187:drug effects / Q000648:ultrastructure; D002462:Cell Membrane / Q000187:drug effects; D002746:Chlorpromazine / Q000494:pharmacology*; D003599:Cytoskeleton / Q000187:drug effects*; D004591:Electrophoresis, Polyacrylamide Gel; D010974:Platelet Aggregation / Q000187:drug effects*; D011817:Rabbits; D052117:Benzodioxoles
D000470:Alkaloids; D016718:Arachidonic Acid; D001095:Arachidonic Acids; D044182:Benzylisoquinolines; D002746:Chlorpromazine; C006947:cepharanthine; D052117:Benzodioxoles