[Effect of arachidonic acid on the physical properties of bilayer and annular lipids of synaptic membranes].
It has been found by fluorescence analysis of pyrene excimerization that arachidonic acid while decreasing microviscosity of lipid bilayer increases it in the annular lipid zone. After incorporation of fatty acid into the membrane the annular lipid acquires the properties of a cooperative system manifested in the appearance of thermal transition near 25 degrees C.
D000818:Animals; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000494:pharmacology*; D005456:Fluorescent Dyes; D066298:In Vitro Techniques; D008051:Lipid Bilayers / Q000032:analysis; D008563:Membrane Lipids / Q000032:analysis*; D008565:Membrane Proteins / Q000032:analysis*; D051381:Rats; D013570:Synaptic Membranes / Q000032:analysis* / Q000187:drug effects
D001095:Arachidonic Acids; D005456:Fluorescent Dyes; D008051:Lipid Bilayers; D008563:Membrane Lipids; D008565:Membrane Proteins; D016718:Arachidonic Acid
Vliianie arakhidonovoĭ kisloty na fizicheskie svoĭstva bisloĭnykh i pribelkovykh lipidov sinapticheskikh membran.