The human placenta: a novel source of inhibin.
Human placental extracts contain inhibin bioactivity and immunoactivity giving dose response curves parallel to a human follicular fluid inhibin standard. Inhibin bioactivity in vitro was neutralised by preincubation of extracts with antisera raised to pure bovine inhibin. Umbilical cord blood from term infants contained immunoactivity. Human placental inhibin differs from human ovarian inhibin in terms of its biological: immunological ratio.
D000818:Animals; D001681:Biological Assay; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D005640:Follicle Stimulating Hormone / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D007231:Infant, Newborn; D007265:Inhibins / Q000096:biosynthesis*; D010902:Pituitary Gland / Q000378:metabolism; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy; D011863:Radioimmunoassay; D051381:Rats
D007265:Inhibins; D005640:Follicle Stimulating Hormone