Inducible macrolides-lincosamides-streptogramin B resistance in Bacteroides species.
The first evidence is presented for the presence of inducible macrolides-lincosamides-streptogramin B resistance in Bacteroides species. Different macrolides induced clindamycin resistance in Bacteroides vulgatus RYC18F6, an erythromycin-resistant and clindamycin-susceptible strain. A study of 144 Bacteroides isolates indicated that erythromycin resistance was linked to diminished clindamycin susceptibility.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001439:Bacteroides / Q000187:drug effects* / Q000235:genetics; D002981:Clindamycin / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D004917:Erythromycin / Q000494:pharmacology*; D005786:Gene Expression Regulation / Q000187:drug effects; D055231:Lincosamides; D018942:Macrolides; D008826:Microbial Sensitivity Tests; D013045:Species Specificity; D014769:Virginiamycin / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D055231:Lincosamides; D018942:Macrolides; D014769:Virginiamycin; D002981:Clindamycin; D004917:Erythromycin