title: [Sensitivity of the pituitary-ovarian system of animals to the nonhormonal preparation RL-S].
abstract: A hypophysis-ovarian system of barren cows was shown to be highly sensitive to the effect of the preparation RL-S. The preparation possessing a simple chemical structure, proved to regulate the functional activity of endocrine glands. After treatment with the preparation RL-S concentration of estradiol was increased 1.81-fold in blood plasma of cows studied as compared with controls, while content of luteinizing hormone was elevated by 12.3%. In the groups of experimental animals the sexual cycle was normalized as content of progesterone was increased in blood with simultaneous decrease in estradiol concentration.
mesh_terms: D000818:Animals; D002417:Cattle; D003338:Corpus Luteum / Q000187:drug effects / Q000503:physiopathology*; D004958:Estradiol / Q000097:blood; D005260:Female; D005300:Fertility Agents, Female / Q000494:pharmacology* / Q000627:therapeutic use; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects / Q000503:physiopathology*; D007247:Infertility, Female / Q000188:drug therapy / Q000503:physiopathology*; D011374:Progesterone / Q000097:blood
chemical_list: D005300:Fertility Agents, Female; D011374:Progesterone; D004958:Estradiol
vernacular_title: Chuvstvitel'nost' gipofizarno-ovarial'noĭ sistemy zhivotnykh k negormonal'nomu preparatu RL-S.