title: Chemical structure and biological activity relationship in bradykinin analogues containing proline-like unusual amino acids.
abstract: Ten different bradykinin analogues have been synthesized and tested for activity on isolated guinea-pig ileum. The results, in comparison with others in the literature, suggest some conclusions on a chemical structure - biological activity relationship.
mesh_terms: D000818:Animals; D001920:Bradykinin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D006168:Guinea Pigs; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects*; D009130:Muscle, Smooth / Q000502:physiology; D010875:Pipecolic Acids; D011392:Proline / Q000031:analogs & derivatives*; D013329:Structure-Activity Relationship
chemical_list: D010875:Pipecolic Acids; D011392:Proline; C010983:homoproline; C031345:pipecolic acid; D001920:Bradykinin