Serologic and protective cross-reactivity of antisera to Pseudomonas aeruginosa extracellular slime glycolipoprotein.
Antisera to extracellular slime glycolipoprotein of Pseudomonas aeruginosa of different O serogroups (immunotypes) show cross reactivity in passive haemagglutination (PHA) and agar gel immunoprecipitation test; cross reactivity is more distinct in PHA. Antisera to glycolipoprotein also have marked cross activity in mouse passive protection test against intraperitoneal challenge with 24 P. aeruginosa strains of different O groups including the toxigenic strain PA-103. On the basis of the results, glycolipoprotein producer P. aeruginosa strains may be selected in order to make a preparation for active and passive immunization against pseudomonas infection.
D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology*; D001426:Bacterial Proteins; D003429:Cross Reactions; D006023:Glycoproteins / Q000276:immunology*; D006386:Hemagglutination Tests; D007106:Immune Sera / Q000276:immunology*; D007116:Immunization, Passive; D005779:Immunodiffusion; D008074:Lipoproteins / Q000276:immunology*; D051379:Mice; D011552:Pseudomonas Infections / Q000276:immunology; D011550:Pseudomonas aeruginosa / Q000276:immunology*
D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D006023:Glycoproteins; D007106:Immune Sera; D008074:Lipoproteins; C025431:extracellular slime proteins, bacterial