title: [Peridural anesthesia with bupivacaine-CO2 and bupivacaine-HCl. A comparative study].
abstract: Carbonated bupivacaine and bupivacaine hydrochloride were used for epidural anaesthesia in patients undergoing surgery of the lower extremities. Thirty patients received 20 ml 0.5% bupivacaine hydrochloride and 32 patients 20 ml 0.42% carbonated bupivacaine. Carbonated bupivacaine had a more rapid onset of action and spread of both sensory and motor blockade than its hydrochloride salt. The differences were statistically significant.
mesh_terms: D000328:Adult; D000767:Anesthesia, Epidural; D002045:Bupivacaine; D002245:Carbon Dioxide; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007866:Leg / Q000294:innervation / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009619:Nociceptors / Q000187:drug effects; D011897:Random Allocation
chemical_list: D002245:Carbon Dioxide; D002045:Bupivacaine
vernacular_title: Periduralanaesthesie mit Bupivacain-CO2 und Bupivacain-HCl. Eine vergleichende Untersuchung.