title: A quantitative study of the effect of terfenadine on cutaneous erythema induced by UVB and UVC radiation.
abstract: Terfenadine, given in sufficient dose to cause maximum H1 receptor blockade, had no effect on the intensity of UVB or UVC erythema measured with a reflectance instrument at 4, 8, and 24 h after irradiation. Histamine, acting on the H1 receptor, is not a significant mediator of UVB or UVC erythema.
mesh_terms: D000328:Adult; D000818:Animals; D001559:Benzhydryl Compounds / Q000627:therapeutic use*; D004307:Dose-Response Relationship, Radiation; D004890:Erythema / Q000139:chemically induced / Q000209:etiology* / Q000473:pathology; D005260:Female; D006632:Histamine / Q000494:pharmacology; D006801:Humans; D008297:Male; D011833:Radiation Injuries, Experimental; D016593:Terfenadine; D014466:Ultraviolet Rays
chemical_list: D001559:Benzhydryl Compounds; D016593:Terfenadine; D006632:Histamine