Hypophosphatemia and acute respiratory failure in a diabetic patient.
A previously healthy 48-year-old male developed diabetic ketoacidosis and severe hypophosphatemia. Within a few hours, acute respiratory insufficiency developed with a marked discrepancy between the pulmonary pathology and the very poor oxygenation seen. We argue that this was due to the effect of hypophosphatemia on respiratory muscle- and heart function and P50, leading to impaired oxygen delivery.
D016883:Diabetic Ketoacidosis / Q000150:complications*; D006439:Hemodynamics; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D010108:Oxyhemoglobins / Q000378:metabolism; D010710:Phosphates / Q000097:blood*; D012131:Respiratory Insufficiency / Q000209:etiology*; D012132:Respiratory Muscles / Q000378:metabolism; D013997:Time Factors
D010108:Oxyhemoglobins; D010710:Phosphates