Enhanced-latex-agglutination assay for C-reactive protein in serum, with use of a centrifugal analyzer.
This is an improved assay of C-reactive protein in serum, for use with the Baker "Encore" centrifugal analyzer. Features of this assay include: 250-specimen throughput per hour, within-batch CV 2.2%, between-batch CV 2.7%, no antigen-excess problems up to 1000 mg/L, negligible interference from rheumatoid factor, and good correlation (r = 0.99) with radial immunodiffusion. The method is inexpensive and automated, involving no predilution steps. It can be adapted for use in a wide range of systems and can be used for single urgent estimations.
D001322:Autoanalysis; D002097:C-Reactive Protein / Q000097:blood*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D005779:Immunodiffusion; D007841:Latex Fixation Tests; D011786:Quality Control; D012016:Reference Values; D012217:Rheumatoid Factor / Q000032:analysis
D002097:C-Reactive Protein; D012217:Rheumatoid Factor