[Oncogenes, their implications in cell growth, differentiation and carcinogenesis].
Cancer Research has changed substantially over the past several years since oncogenes were isolated from cancer cells. More than 40 oncogenes have been identified to date from tumor viruses and cancer cells. Many of the gene products seem related to signalling pathways that determine growth and differentiation of cells. This review attempts to summarize much of the currently available data and to gain future perspectives.
D015127:9,10-Dimethyl-1,2-benzanthracene; D000818:Animals; D002273:Carcinogens; D002471:Cell Transformation, Neoplastic; D002472:Cell Transformation, Viral; D004815:Epidermal Growth Factor / Q000235:genetics; D005814:Genes, Viral; D006801:Humans; D008325:Mammary Neoplasms, Experimental / Q000139:chemically induced / Q000235:genetics; D009369:Neoplasms / Q000209:etiology* / Q000473:pathology; D010982:Platelet-Derived Growth Factor / Q000235:genetics; D012190:Retroviridae / Q000235:genetics; D014162:Transfection; D001749:Urinary Bladder Neoplasms / Q000235:genetics
D002273:Carcinogens; D010982:Platelet-Derived Growth Factor; D015127:9,10-Dimethyl-1,2-benzanthracene; D004815:Epidermal Growth Factor