Acute myelomonocytic leukaemia and acquired haemophilia A with severe cutaneous haemorrhage.
A case of severe cutaneous haemorrhage due to thrombocytopenia in combination with an acquired haemophilia A is reported. The thrombocytopenia was due to acute myelomonocytic leukaemia (FAB M4). A factor VIII:C specific anticoagulant was also found. Chemotherapy led to complete remission with normal blood counts and coagulation-test results.
D001327:Autoimmune Diseases / Q000209:etiology; D005169:Factor VIII / Q000032:analysis / Q000037:antagonists & inhibitors; D005260:Female; D006467:Hemophilia A / Q000209:etiology*; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008875:Middle Aged; D012871:Skin Diseases / Q000209:etiology; D013921:Thrombocytopenia / Q000209:etiology*
D005169:Factor VIII