[Histometric studies of placental villi in Rh incompatibility].
The delay in maturation of placental terminal villi in cases of Rh-incompatibility has often been described. The terminal villi of sixteen placentas from pregnancies complicated by Rh-incompatibility histometric were studied. Twenty-two placentas of healthy mothers who had born healthy babies after normal pregnancies served as a control group. The severity of the Rh-incompatibility was classified according to the clinical histories of the newborns and the criteria of Liley. The average area of a cross-section of a terminal villus was 3402 microns 2 (control group 2150 micronsoff; the degree of vascularization was calculated to be 6.5% (control group 30.5%). The other villous parameters measured or calculated show that maturation of the placenta is extremely retarded in cases of Rh-incompatibility. This failure in differentiation can not be compensated for by an enlargement of the organ as a whole. It was shown that the changes in the placental villi are closely correlated to the severity of the fetal disease.
D001724:Birth Weight; D002196:Capillaries / Q000473:pathology; D002824:Chorionic Villi / Q000098:blood supply / Q000473:pathology*; D004848:Epithelium / Q000473:pathology; D004899:Erythroblastosis, Fetal / Q000473:pathology*; D005260:Female; D005317:Fetal Growth Retardation / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D012203:Rh Isoimmunization / Q000473:pathology*
Histometrische Untersuchungen an Plazentazotten bei Rh-Inkompatibilität.