[Cutaneous apoprotein B and coronary atherosclerosis].
Cutaneous and plasma lipids (cholesterol and Apoprotein B) were studied in 2 populations (average age 57.5 years), one with pathological and the other with normal coronary angiography. Skin biopsy was performed during the incision of thoracotomy. The concentrations of Apo B and cholesterol in the skin were compared to those of plasma lipids, lipoproteins and apoprotein B for the diagnosis of atherosclerosis. This study showed that skin Apo B was the best marker of coronary atherosclerosis in patients with plasma Apo B concentrations of less than 1.3 g/l. The skin Apo B concentration was closely correlated to the presence but not to the severity of this arterial pathology. The cardiovascular risk factors of this population, studied separately and in a cumulative manner, confirmed the results of previously published reports.
D001055:Apolipoproteins B / Q000032:analysis* / Q000097:blood; D002784:Cholesterol / Q000097:blood; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000378:metabolism*; D006801:Humans; D008055:Lipids / Q000097:blood; D008875:Middle Aged; D012306:Risk; D012867:Skin / Q000378:metabolism*
D001055:Apolipoproteins B; D008055:Lipids; D002784:Cholesterol
Apoprotéine B cutanée et athérosclérose coronarienne.