title: Dose-duration effect of sodium cromoglycate aerosol in exercise-induced asthma.
abstract: The dose-duration effect of sodium cromoglycate given by metered dose aerosol was studied in nine patients with exercise-induced asthma. Exercise tests were carried out at 15, 135 and 255 min after placebo, sodium cromoglycate 2 mg, 10 mg and 20 mg. The protective effect and the duration of action were dose-related. The new metered dose aerosol delivering 5 mg of sodium cromoglycate per actuation allows greater flexibility in adjusting the dosage and frequency of administration for individual patients.
mesh_terms: D000280:Administration, Inhalation; D000293:Adolescent; D000328:Adult; D000336:Aerosols; D001249:Asthma / Q000188:drug therapy*; D001250:Asthma, Exercise-Induced / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004205:Cromolyn Sodium / Q000008:administration & dosage / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011897:Random Allocation
chemical_list: D000336:Aerosols; D004205:Cromolyn Sodium