Crying-induced bronchospasm in childhood asthma: response to nebulized metaproterenol 5% and sodium cromoglycate 1%.
Five asthmatic children (2 to 5 years) with persistent crying-induced bronchospasm refractory to concomitant oral theophylline and metaproterenol for 4 weeks were selected for an 8-week uncontrolled study with nebulized metaproterenol 5% and sodium cromoglycate 1%. All five patients had reduction in both crying and non-crying-related asthma. Three patients had reduction in crying behavior. Nebulized metaproterenol and sodium cromoglycate may be effective in treating crying-induced bronchospasm refractory to oral bronchodilators.
D000284:Administration, Oral; D000336:Aerosols; D001249:Asthma / Q000188:drug therapy* / Q000209:etiology; D002675:Child, Preschool; D004205:Cromolyn Sodium / Q000008:administration & dosage*; D003448:Crying; D006801:Humans; D009921:Metaproterenol / Q000008:administration & dosage*; D013806:Theophylline / Q000008:administration & dosage
D000336:Aerosols; D009921:Metaproterenol; D013806:Theophylline; D004205:Cromolyn Sodium