[Functions of the stomach after parasympathetic denervation of the fundus and uncoupling of the fundus and antral portions].
Selective proximal vagotomy (SPV) evoked the same alterations in the motility of fundal part of the dog stomach as truncal vagotomy. Within 2-3 months the fundal motility was completely normalized. If the SPV were carried out with preserved innervation in the cardial zone, the motility restoration was accelerated to 7-10 days. But is SPV was added to the disconnection of antral part with proximal stomach, its motility did not restore at all. SPV initially suppressed the insulin secretion to 70-85 per cent; in 6-12 months this suppression decreased to 60 per cent and stabilized on this level. The Auerbach plexus seems to differ from the Meissner plexus in that the former can transfer the gaval influence from the innervated zone into the denervated one. Judging by the functional indices the growth of vagal fibers from the innervated zone into the denervated one did not take place.
D000818:Animals; D004285:Dogs; D005744:Gastric Acid / Q000378:metabolism; D005748:Gastric Fundus / Q000294:innervation; D005769:Gastrointestinal Motility; D006584:Hexamethonium Compounds / Q000494:pharmacology; D007328:Insulin / Q000378:metabolism; D000078790:Insulin Secretion; D010434:Pepsin A / Q000378:metabolism; D011706:Pyloric Antrum / Q000294:innervation; D013270:Stomach / Q000294:innervation*; D014629:Vagotomy, Proximal Gastric
D006584:Hexamethonium Compounds; D007328:Insulin; D010434:Pepsin A; C021628:benzohexonium
Funktsii zheludka pri parasimpaticheskoĭ denervatsii fundal'nogo otdela i razobshchenii fundal'nogo otdela s antral'nym.