Gold pneumonitis. A case report with electronmicroscopy and electron probe analysis.
A case of classical RA developed severe interstitial pulmonary disease and respiratory failure while on chrysotherapy. A high concentration of gold was found in lung tissue. Electron microscopic and electron probe examinations confirmed the presence of gold in the interstitial and intra-alveolar macrophages. The clinical course and possible pathogenic mechanism were discussed.
D000368:Aged; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D004577:Electron Probe Microanalysis; D006052:Gold Sodium Thiomalate / Q000009:adverse effects* / Q000378:metabolism; D006801:Humans; D008168:Lung / Q000378:metabolism; D008297:Male; D011014:Pneumonia / Q000139:chemically induced* / Q000473:pathology
D006052:Gold Sodium Thiomalate