Membrane lipid peroxidation in erythrocytes of the newborn.
Fresh, untreated neonatal erythrocytes contained nearly two times the adult level of thiobarbituric acid-reactivity, an index of lipid peroxidation. In addition, both fluorescence and the phospholipid:MDA adduct were significantly increased in neonatal erythrocytes. This study suggests that neonatal erythrocytes undergo significant peroxidative membrane lipid damage in vivo.
D004492:Edetic Acid / Q000494:pharmacology; D004910:Erythrocyte Membrane / Q000032:analysis / Q000378:metabolism*; D005312:Fetal Blood / Q000378:metabolism*; D006801:Humans; D007231:Infant, Newborn; D008054:Lipid Peroxides / Q000378:metabolism*; D008563:Membrane Lipids / Q000378:metabolism*; D010743:Phospholipids / Q000032:analysis
D008054:Lipid Peroxides; D008563:Membrane Lipids; D010743:Phospholipids; D004492:Edetic Acid