title: [Operon of riboflavin biosynthesis in Bacillus subtilis. XVII. A study of the regulatory functions of the intermediate products and their derivatives].
abstract: Repression of synthesis of GTP-cyclohydrolase and riboflavinsynthetase was studied in different regulatory mutants of Bacillus subtilis. The results of experiments with some riboflavin precursors and their derivatives revealed that 5-amino-2,6-dioxo-4-ribitylaminopyrimidine and 6-methyl-7-(1',2'-dioxyethyl)-8-ribityllumazine can serve as effectors in riboflavin biosynthesis.
mesh_terms: D001412:Bacillus subtilis / Q000201:enzymology / Q000235:genetics*; D004792:Enzyme Precursors / Q000378:metabolism; D004794:Enzyme Repression; D006136:GTP Cyclohydrolase / Q000032:analysis / Q000096:biosynthesis; D005809:Genes, Regulator; D009154:Mutation; D009876:Operon; D011621:Pteridines / Q000378:metabolism; D012256:Riboflavin / Q000096:biosynthesis* / Q000235:genetics; D012258:Riboflavin Synthase / Q000032:analysis / Q000096:biosynthesis; D013056:Spectrophotometry, Ultraviolet; D014529:Uridine / Q000031:analogs & derivatives / Q000235:genetics / Q000378:metabolism
chemical_list: D004792:Enzyme Precursors; D011621:Pteridines; C040523:5-amino-6-ribitylamino-2,4-(1H,3H)pyrimidinedione; C049782:6-methyl-7-(1',2'-dihydroxyethyl)-8-ribityllumazine; D012258:Riboflavin Synthase; D006136:GTP Cyclohydrolase; D012256:Riboflavin; D014529:Uridine
vernacular_title: Issledovanie operona biosinteza riboflavina u Bacillus subtiis. Soobshchenie XVII. Izuchenie reguliatornykh funktsiĭ promezhutochnykh produktov i ikh proizvodnykh.