[Immunosuppression by retroviruses in tumors and immune deficiency diseases].
Most retroviruses are immunosuppressive in vitro and in vivo. They are able to enhance virus-induced tumor development and/or to induce acquired immune deficiency syndromes (AIDS) which are characterized by malignant tumors and opportunistic infections. Experimental evidence for the immunosuppressive properties of several type D viruses derived from human cell lines and other retroviruses is presented.
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology*; D000818:Animals; D002417:Cattle; D003208:Concanavalin A / Q000494:pharmacology; D000882:Haplorhini; D006801:Humans; D007108:Immune Tolerance; D008213:Lymphocyte Activation / Q000187:drug effects; D051379:Mice; D009369:Neoplasms / Q000276:immunology; D009374:Neoplasms, Experimental / Q000276:immunology*; D010835:Phytohemagglutinins / Q000494:pharmacology; D012190:Retroviridae / Q000276:immunology*; D013045:Species Specificity
D010835:Phytohemagglutinins; D003208:Concanavalin A
Immunosuppression durch Retroviren bei Tumoren und Immundefizienzerkrankungen.