Excretion of octopamine metabolites in neuroblastoma.
The urinary concentrations of o-hydroxymandelic acid, m-hydroxymandelic acid, p-hydroxymandelic acid, homovanillic acid and vanillylmandelic acid were determined in 57 healthy children and 9 patients with neuroblastoma. The concentrations of o-hydroxymandelic acid and p-hydroxymandelic were not significantly different for both groups whereas the concentrations of m-hydroxymandelic acid, homovanillic acid and vanillylmandelic acid were elevated 20- to 30-fold in the neuroblastoma patients.
D015078:2-Hydroxyphenethylamine / Q000031:analogs & derivatives / Q000378:metabolism; D002675:Child, Preschool; D005260:Female; D006719:Homovanillic Acid / Q000652:urine*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008333:Mandelic Acids / Q000652:urine*; D009447:Neuroblastoma / Q000652:urine*; D009638:Norepinephrine / Q000378:metabolism; D009655:Octopamine / Q000378:metabolism / Q000031:analogs & derivatives; D014642:Vanilmandelic Acid / Q000652:urine*
D008333:Mandelic Acids; C014600:4-hydroxymandelic acid; D009655:Octopamine; C024037:3-hydroxymandelic acid; C024038:2-hydroxymandelic acid; D014642:Vanilmandelic Acid; D015078:2-Hydroxyphenethylamine; C005310:norfenefrine; D009638:Norepinephrine; D006719:Homovanillic Acid