title: Antenatal sonographic diagnosis of congenital clubfoot: a possible indication for amniocentesis.
abstract: Eighteen cases of congenital clubfoot were diagnosed sonographically between 16 and 38 weeks. The method of diagnosis, associated anomalies, karyotypes, and obstetric outcomes are described. Fifteen of the 18 fetuses had other major congenital anomalies, and of these, four had abnormal karyotypes. Only three had uncomplicated clubfoot as the only abnormality. Because of the significant incidence of abnormal karyotypes in our series, confirmed in other reported cases, identification of a clubfoot on prenatal sonography may be considered an indication for amniocentesis, particularly when other anomalies are present.
mesh_terms: D000328:Adult; D000649:Amniocentesis; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D003025:Clubfoot / Q000175:diagnosis* / Q000196:embryology / Q000235:genetics; D005260:Female; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D014463:Ultrasonography