Primary angiosarcoma of the gingiva. Case report with immunohistochemical study.
A case of angiosarcoma involving primarily the gingiva in an 86-year-old woman is reported. The neoplasm was strongly positive for factor VIII-related antigen, negative for cytokeratins, and positive for vimentin, confirming the vascular nature of the tumor. The patient died from heart failure 1 month after surgical excision of the lesion without clinical evidence of metastasis.
D000368:Aged; D000369:Aged, 80 and over; D000941:Antigens / Q000378:metabolism; D002196:Capillaries / Q000473:pathology; D004727:Endothelium / Q000473:pathology; D005169:Factor VIII / Q000276:immunology / Q000378:metabolism; D005260:Female; D005881:Gingiva / Q000473:pathology; D005887:Gingival Neoplasms / Q000473:pathology*; D006394:Hemangiosarcoma / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D014841:von Willebrand Factor
D000941:Antigens; D014841:von Willebrand Factor; D005169:Factor VIII