title: The effect of age, gender, and sexual maturation on the caffeine breath test.
abstract: This study demonstrated the feasibility of utilizing the (3-13C-methyl) caffeine breath test (CBT) in children and adolescents, and examined the effect of gender, age, and puberty on the CBT. The CBT, expressed as the 2-hour accumulative exhalation of labeled CO2 (2-hour CO2), was compared to the CBT results in the adult. The 2-hour CO2 values were higher in the children than the adult, and the decrease in the CO2 values occurred in males during late puberty and in females during early puberty.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000375:Aging; D001944:Breath Tests / Q000379:methods*; D002110:Caffeine / Q000378:metabolism*; D002245:Carbon Dioxide / Q000378:metabolism*; D002648:Child; D002675:Child, Preschool; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D012737:Sex Factors; D012741:Sexual Maturation
chemical_list: D002245:Carbon Dioxide; D002110:Caffeine; D003577:Cytochrome P-450 Enzyme System