Effect of ciprofloxacin on carrier rate of Neisseria meningitidis in army recruits in Finland.
The efficacy of ciprofloxacin in eradicating pharyngeal colonization of Neisseria meningitidis was studied among army recruits in Finland. Ciprofloxacin (250 mg) or placebo was given twice a day for 2 days to 118 meningococcal carriers. Meningococcal carriage was eradicated in 96% of subjects given ciprofloxacin and in 13% of those given placebos.
D002353:Carrier State / Q000188:drug therapy* / Q000382:microbiology; D002939:Ciprofloxacin / Q000627:therapeutic use*; D005387:Finland; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008889:Military Personnel; D009345:Neisseria meningitidis / Q000187:drug effects; D010614:Pharynx / Q000382:microbiology
D002939:Ciprofloxacin