[Demonstration of ligands for antibodies against the M protein on the virion surface of the Newcastle disease virus (NDV)].
Demonstrated was the presence of ligands for antibodies to the M-protein on the surface of NDV virions, using the hemagglutination-inhibition reaction, the immunodiffusion test in agar gel, the indirect variant of the enzyme-linked immunosorbent assay, and the immunosorbent micromethod with nitrocellulose membranes. Data spoke of transmembrane interactions between the M-protein and the glycoproteins of the envelope, which was of basic importance with regard to the biologic role played by this essential structural virus protein. The presence of ligands made it reasonable to believe that the M-protein played a part in the building up of antiviral immunity.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D006387:Hemagglutination, Viral; D005779:Immunodiffusion; D007124:Immunoenzyme Techniques; D007163:Immunosorbent Techniques; D008024:Ligands; D009522:Newcastle disease virus / Q000276:immunology*; D011817:Rabbits; D013499:Surface Properties; D014763:Viral Matrix Proteins; D014764:Viral Proteins / Q000276:immunology* / Q000302:isolation & purification; D014771:Virion / Q000276:immunology*
D000914:Antibodies, Viral; D008024:Ligands; D014763:Viral Matrix Proteins; D014764:Viral Proteins
Dokazvane na ligandi za antitela sreshtu M-proteina vŭrkhu povŭrkhnostta na virionite na virusa na Niukiasŭlskata bolest (NDV).