[Disorders of repair processes in the lymphocytes of schizophrenia patients, cultured in vitro].
Repair disorders of DNA damage induced by gamma-radiation and 4-nitroquinoline-1-oxide treatment in cultivated lymphocytes of patients with schizophrenia. 13 criteria were used for estimation of repair activity (reactivation of viral host cells) repair synthesis, reparation of DNA breaks, formation of spontaneous and induced sister chromatid exchanges.
D015112:4-Nitroquinoline-1-oxide / Q000494:pharmacology; D002478:Cells, Cultured; D004249:DNA Damage; D004260:DNA Repair / Q000187:drug effects / Q000528:radiation effects; D004277:DNA, Single-Stranded / Q000096:biosynthesis* / Q000187:drug effects / Q000528:radiation effects; D005720:Gamma Rays; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism* / Q000528:radiation effects; D009153:Mutagens / Q000494:pharmacology; D012559:Schizophrenia / Q000097:blood*; D012854:Sister Chromatid Exchange / Q000187:drug effects / Q000528:radiation effects; D014466:Ultraviolet Rays; D014780:Viruses
D004277:DNA, Single-Stranded; D009153:Mutagens; D015112:4-Nitroquinoline-1-oxide
Narusheniia protsessov reparatsii v limfotsitakh bol'nykh shizofrenieĭ, kul'tiviruemykh in vitro.