Successful preoperative apheresis of factor VIII antibody using factor VIII concentrate as a replacement fluid.
Plasma exchange was performed on a patient with hemophilia A and inhibitor to factor VIIIC prior to bilateral cataract removal. Koate was used as replacement fluid with effective reduction of the inhibitor level. From the technical standpoint we found out that factor VIII is best reconstituted in water and directly infused through the venous line and not the centrifuge bowl.
D000328:Adult; D000906:Antibodies / Q000302:isolation & purification; D001781:Blood Component Removal; D002387:Cataract Extraction; D005169:Factor VIII / Q000008:administration & dosage* / Q000276:immunology / Q000302:isolation & purification*; D006467:Hemophilia A / Q000097:blood / Q000150:complications / Q000628:therapy*; D006801:Humans; D008297:Male; D011300:Preoperative Care
D000906:Antibodies; D005169:Factor VIII