title: Synteny of SIS and IGLC in owl monkeys. Evidence for karyotype evolution.
abstract: Two cloned human DNA sequences specific for the SIS and IGLC genes were hybridized with DNAs from panels of rodent-owl monkey somatic cell hybrids. Independent segregation analysis of the related owl monkey DNA sequences for these two genes demonstrated that both the SIS locus and the IGLC locus are localized on owl monkey chromosome 3 of karyotype VI, chromosome 3 of karyotype V, and chromosome 6 of karyotype IV. These syntenic assignments provide genetic evidence for the homology of, at least, a portion of these chromosomes from three owl monkey karyotypes. The findings also help to redetermine the possible chromosome rearrangement that characterized the chromosome complement of owl monkey from Panama and northwestern Colombia with karyotypes II, III, IV, VIII, and IX from other owl monkey populations with karyotypes I, V, VI, VII, X, and XI.
mesh_terms: D000818:Animals; D001029:Aotus trivirgatus / Q000235:genetics*; D002427:Cebidae / Q000235:genetics*; D002460:Cell Line; D002874:Chromosome Mapping; D005796:Genes; D006822:Hybrid Cells; D007127:Immunoglobulin Constant Regions / Q000235:genetics; D007146:Immunoglobulin lambda-Chains / Q000235:genetics; D007621:Karyotyping
chemical_list: D007127:Immunoglobulin Constant Regions; D007146:Immunoglobulin lambda-Chains