title: The histological and ultrastructural features of the epiphyseal plate in Morquio type A syndrome (mucopolysaccharidosis type IVA).
abstract: Tissue from the epiphyseal plate of a patient with Morquio type A syndrome (mucopolysaccharidosis type IVA) was studied by undecalcified histological and electron microscopical techniques. Cartilage cells in the plate were vacuolated to a variable degree. The orderly proliferating structure of the epiphyseal plate was absent and calcification was markedly reduced. The related bone tissue was morphologically normal although reduced in quantity.
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006025:Glycosaminoglycans / Q000032:analysis; D006132:Growth Plate / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009085:Mucopolysaccharidosis IV / Q000473:pathology*
chemical_list: D006025:Glycosaminoglycans