title: Technique of experimental aneurysm formation in the rat common carotid artery using the milliwatt carbon dioxide laser and the adventitia patch model.
abstract: Aneurysms were induced in the rat common carotid artery by using the milliwatt carbon dioxide laser to weld an adventitia patch over a hole. This technique proved to be effective and reliable as demonstrated by the 100% incidence of aneurysm formation at the patch site in 28 rats killed 1 week or later after the procedure. It is suggested that this technique may be used to produce intracranial aneurysms in experimental animals due to the minimal vessel manipulation required.
mesh_terms: D000783:Aneurysm / Q000473:pathology; D000818:Animals; D002245:Carbon Dioxide; D002339:Carotid Arteries / Q000601:surgery; D002340:Carotid Artery Diseases / Q000473:pathology; D003238:Connective Tissue / Q000473:pathology; D004195:Disease Models, Animal; D007834:Lasers; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D002245:Carbon Dioxide