[Macular manifestations of monoclonal dysgammaglobulinemias. Apropos of 3 cases].
Macular oedema is one of the scarcely known manifestations of monoclonal dysglobulinemia. It is most common in Waldenström's macroglobulinemia because the serum's viscosity may reach a very high level, but it occurs also in multiple myeloma (first case described here). This specific oedema is secondary to immunoglobulin deposits in retinal layers and subretinal space. Early treatment is necessary to prevent irreversible visual loss, especially because the patient's expected life span becomes lengthened. Plasmaphereses are very useful in reducing serum's hyperviscosity, and rapidly improve most of the ocular manifestations.
D000368:Aged; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008266:Macula Lutea / Q000473:pathology; D008269:Macular Edema / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000473:pathology; D014786:Vision Disorders / Q000517:prevention & control; D008258:Waldenstrom Macroglobulinemia / Q000150:complications* / Q000473:pathology
Manifestations maculaires des dysglobulinémies monoclonales. A propos de trois cas.