CO2 vulnerability in panic disorder.
The immediate effects of a single inhalation of a 35% CO2 mixture in oxygen were examined in 12 patients with panic disorders and 11 normal control subjects. Compared to a placebo air inhalation, the CO2 inhalation provoked short-lived autonomic panic symptoms in both patients and normals; it also elicited high subjective anxiety in patients with panic disorders. The latter rated the overall CO2-induced state as very similar to a real-life panic attack.
D000328:Adult; D001008:Anxiety Disorders / Q000503:physiopathology*; D001341:Autonomic Nervous System / Q000503:physiopathology*; D002245:Carbon Dioxide; D005239:Fear / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D010200:Panic / Q000502:physiology*
D002245:Carbon Dioxide