[Effect of newborn rat testes on the male sexual behavior of the testosterone-treated adult].
Neonatal male rats were castrated either at 0, 6 or 24 hrs. after birth. As adults, testosterone was delivered by subcutaneous implantation of a Silastic capsule containing this hormone. The probability to display mounting behavior in presence of an estrous female was lower when the animals were castrated at 0 hr. than at 6 or 24 hrs. or when they received a subcutaneous injection of 1 microgram of testosterone propionate, at the time of castration at 0 hr. These results suggest that in the rat, during the 6 hrs. following birth, neonatal testes influence the sensitivity of the adult central nervous system to testosterone.
D000818:Animals; D000831:Animals, Newborn; D003692:Delayed-Action Preparations; D008297:Male; D009919:Orchiectomy; D051381:Rats; D011919:Rats, Inbred Strains; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D012826:Silicone Elastomers; D013737:Testis / Q000502:physiology*; D013739:Testosterone / Q000494:pharmacology*; D014020:Tissue Extracts / Q000494:pharmacology
D003692:Delayed-Action Preparations; D012826:Silicone Elastomers; D014020:Tissue Extracts; D013739:Testosterone
Influence des testicules du rat nouveau-né sur le comportement sexuel mâle de l'adulte soumis à la testostérone.