'Lupus' anticoagulant and thrombosis of the hepatic veins (Budd-Chiari syndrome). Report of three patients and review of the literature.
Three patients with Budd-Chiari syndrome in association with the 'lupus' anticoagulant are described. This anticoagulant was looked for in our patients with an otherwise idiopathic hepatic venous thrombosis because of the presence of a pronounced thrombocytopenia, a prolonged activated partial thromboplastin time or a history of repeated abortions and deep leg vein thrombosis, respectively. An active search for the 'lupus' anticoagulant should be performed to lower the percentage of apparently idiopathic cases of Budd-Chiari syndrome.
D000328:Adult; D001706:Biopsy; D001778:Blood Coagulation Disorders / Q000150:complications; D001779:Blood Coagulation Factors / Q000032:analysis / Q000037:antagonists & inhibitors*; D006502:Budd-Chiari Syndrome / Q000097:blood* / Q000209:etiology / Q000473:pathology; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D016682:Lupus Coagulation Inhibitor; D008297:Male; D008875:Middle Aged
D001779:Blood Coagulation Factors; D016682:Lupus Coagulation Inhibitor