Does sodium cromoglycate have an effect on contact dermatitis?
Sodium cromoglycate was applied to the forearm of 9 subjects with known delayed hypersensitivity, and to the back of 14 dinitrochlorobenzene-sensitized guinea pigs before challenge with the allergen and sodium lauryl sulphate. Sodium cromoglycate did not decrease the intensity of allergic of toxic-irritant reactions in either humans or guinea pigs.
D000279:Administration, Cutaneous; D000293:Adolescent; D000328:Adult; D000818:Animals; D004205:Cromolyn Sodium / Q000008:administration & dosage / Q000627:therapeutic use*; D003877:Dermatitis, Contact / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D007509:Irritants / Q000009:adverse effects; D008297:Male; D008875:Middle Aged
D007509:Irritants; D004205:Cromolyn Sodium