title: Delayed recovery of CO2 reactivity after one hour's complete ischaemia of cat brain.
abstract: The cerebrovascular CO2 reactivity was examined after 6 h, 1, 2, and 3 days and 1 year following 1 h complete brain ischaemia in the cat. After 6 h recirculation, the CO2 reactivity was completely suppressed although major EEG activity had recovered. After 2 days, CO2 reactivity began to reappear, but even after 1 year restitution was not complete. The prolonged (though partly reversible) attenuation of CO2 responsiveness suggests that ischaemia is followed by a long-lasting state of haemodynamic imbalance, which may be responsible for the slow progress of post-ischaemic recovery processes.
mesh_terms: D000818:Animals; D002545:Brain Ischemia / Q000503:physiopathology*; D002245:Carbon Dioxide; D002415:Cats; D002560:Cerebrovascular Circulation; D004569:Electroencephalography; D005260:Female; D008297:Male; D012119:Respiration; D014980:Xenon Radioisotopes
chemical_list: D014980:Xenon Radioisotopes; D002245:Carbon Dioxide