Use of gonozyme on urine sediment for diagnosis of gonorrhea in males.
We compared enzyme immunoassay (Gonozyme; Abbott Laboratories, North Chicago, Ill.) for detection of gonococcal antigen in urine sediments with urethral swab culture for diagnosis of gonorrhea in men attending a venereal disease clinic. The prevalence of infection was 14% by culture (27/196). The sensitivity of enzyme immunoassay was 93% (25/27) compared with the culture method, and the specificity was 99% (167/169). The ability to detect gonococcal antigen in urine sediment may provide the basis for a noninvasive method of screening for gonococcal infection.
D000942:Antigens, Bacterial / Q000652:urine*; D005189:False Positive Reactions; D005840:Gentian Violet; D006069:Gonorrhea / Q000175:diagnosis* / Q000382:microbiology / Q000652:urine; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D009344:Neisseria gonorrhoeae / Q000276:immunology* / Q000302:isolation & purification; D010619:Phenazines; D014521:Urethra / Q000382:microbiology
D000942:Antigens, Bacterial; C035863:Gram's stain; D010619:Phenazines; D005840:Gentian Violet