Type VI collagen represents a major fraction of connective tissue collagens.
A new method for the isolation of type VI collagen from peptic tissue digests is presented which gives tenfold higher yields than methods previously reported. From the amounts of purified protein obtained from human placenta, bovine uterus, chicken gizzard and entire mouse bodies we conclude that type VI collagen represents a major fraction of connective tissue collagens.
D000818:Animals; D002417:Cattle; D002645:Chickens; D003094:Collagen / Q000145:classification / Q000302:isolation & purification*; D003238:Connective Tissue / Q000032:analysis*; D005260:Female; D005895:Gizzard, Avian / Q000032:analysis; D006801:Humans; D051379:Mice; D010434:Pepsin A; D010920:Placenta / Q000032:analysis; D011247:Pregnancy; D013816:Thermodynamics; D014599:Uterus / Q000032:analysis
D003094:Collagen; D010434:Pepsin A