title: Demonstration of thyrotropin-releasing hormone immunoreactivity in neurons of the mouse spinal dorsal horn.
abstract: Thyrotropin-releasing hormone-like immunoreactivity was demonstrated in neurons within the superficial laminae (I, II, III) of the mouse spinal dorsal horn by light-microscopic peroxidase immunocytochemistry. The immunoreactivity was distributed in a narrow dorsoventral band that enclosed the substantia gelatinosa (lamina II), with a higher concentration along the lamina II/III border. At present, the functional significance of these neurons is unknown. Their existence within the substantia gelatinosa suggests a role in sensory information processing.
mesh_terms: D000818:Animals; D007124:Immunoenzyme Techniques; D051379:Mice; D009474:Neurons / Q000276:immunology / Q000378:metabolism; D013116:Spinal Cord / Q000276:immunology / Q000378:metabolism*; D013973:Thyrotropin-Releasing Hormone / Q000276:immunology / Q000378:metabolism*
chemical_list: D013973:Thyrotropin-Releasing Hormone