Otosurgical model in the guinea pig (Cavia porcellus).
The guinea pig is a useful model for otologic research. Common problems encountered in working with individual animals include preexisting chronic middle ear disease, anesthetic deaths, and a lack of knowledge of the surgical anatomy and landmarks of the middle and inner ear. The methods detailed in this article will benefit those interested in a reliable, inexpensive, otosurgical animal model.
D000758:Anesthesia / Q000379:methods; D000818:Animals; D004195:Disease Models, Animal; D004427:Ear Diseases / Q000601:surgery*; D007758:Ear, Inner / Q000033:anatomy & histology / Q000601:surgery; D004432:Ear, Middle / Q000033:anatomy & histology / Q000601:surgery; D005154:Facial Nerve / Q000033:anatomy & histology / Q000601:surgery; D006168:Guinea Pigs