The aurachins, new quinoline antibiotics from myxobacteria: production, physico-chemical and biological properties.
The aurachins, new quinoline alkaloids, were extracted with acetone from the biomass of the myxobacterium, Stigmatella aurantiaca strain Sg a15 and purified by column chromatography. The four described aurachins A, B, C and D, were inhibitory for Gram-positive bacteria and a few yeasts and molds. They blocked NADH oxidation in beef heart submitochondrial particles.
D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D005285:Fermentation; D008826:Microbial Sensitivity Tests; D009231:Myxococcales / Q000378:metabolism; D011804:Quinolines / Q000302:isolation & purification / Q000494:pharmacology; D015363:Quinolones; D013055:Spectrophotometry, Infrared
D000900:Anti-Bacterial Agents; D011804:Quinolines; D015363:Quinolones; C052095:aurachin B; C052097:aurachin D; C052096:aurachin C; C052094:aurachin A