Effect of fagaronine on chromosome breaks and loss in Drosophila melanogaster.
Fagaronine, a potent antileukemic agent, was shown to induce chromosome breaks and loss in sperm of Drosophila melanogaster.
D000470:Alkaloids / Q000494:pharmacology*; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D053119:Benzophenanthridines; D002869:Chromosome Aberrations; D004331:Drosophila melanogaster / Q000187:drug effects / Q000235:genetics; D008297:Male; D009152:Mutagenicity Tests; D009153:Mutagens; D010617:Phenanthridines; D013094:Spermatozoa / Q000187:drug effects
D000470:Alkaloids; D000970:Antineoplastic Agents; D053119:Benzophenanthridines; D009153:Mutagens; D010617:Phenanthridines; C002066:fagaronine