Effect of acidity and antimicrobial agent-like compounds on viability of Plesiomonas shigelloides.
Nineteen Plesiomonas shigelloides strains were evaluated for their stability at acidic and slightly alkaline pHs and for their susceptibility to antimicrobial agent-like compounds produced by enteric flora. Most P. shigelloides isolates were rapidly inactivated under high-acid (pH 4 or less) conditions. Screening of enteric bacteria for elaboration of factors active against P. shigelloides revealed two organisms (Pseudomonas aeruginosa and Streptococcus [Enterococcus] faecium) capable of secreting such inhibitory substances. The results of this study suggest some factors potentially important in regulating gastrointestinal colonization by P. shigelloides from environmental sources.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000898:Antibiosis; D018407:Bacterial Physiological Phenomena; D004755:Enterobacteriaceae / Q000502:physiology*; D006863:Hydrogen-Ion Concentration; D011550:Pseudomonas aeruginosa / Q000502:physiology; D013210:Staphylococcus / Q000502:physiology; D013291:Streptococcus / Q000502:physiology; D014737:Vibrionaceae / Q000187:drug effects / Q000254:growth & development*
D000900:Anti-Bacterial Agents