Posttraumatic Bacillus cereus endophthalmitis.
We encountered a patient who developed Bacillus cereus endophthalmitis following trauma. Early therapy, which included intravitreal clindamycin phosphate and gentamicin sulfate, resulted in a visual acuity of 20/60. A five-year retrospective review of all cases of endophthalmitis following trauma reported at our institution revealed Bacillus as the infecting organism in six (46%) of 13 culture-positive cases. The high frequency of virulent Bacillus infections in the setting of trauma necessitates the use of antibiotics that are active against this organism in posttraumatic endophthalmitis. The combination of clindamycin and gentamicin can be effective therapy in Bacillus species infections if used early in the course of the disease.
D000062:Accidents, Occupational; D000328:Adult; D000382:Agricultural Workers' Diseases / Q000188:drug therapy / Q000209:etiology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001409:Bacillus cereus; D001424:Bacterial Infections / Q000188:drug therapy / Q000209:etiology*; D009877:Endophthalmitis / Q000188:drug therapy / Q000209:etiology*; D005131:Eye Injuries / Q000150:complications*; D006801:Humans; D008297:Male; D014792:Visual Acuity; D014950:Wounds, Penetrating / Q000150:complications*
D000900:Anti-Bacterial Agents