[Regression of IgA kappa monoclonal gammopathy in IgA lambda Kahler's disease].
The authors report the case of a patient with a stable IgA kappa gammapathy over several years which finally evolved to an IgA lambda myeloma during which the initial gammapathy regressed. As the two gammapathies probably arose from two different cellular populations, the regression of the IgA kappa dysglobulinaemia is an additional argument in favour of the hypothesis that benign monoclonal gammapathies are the result of cellular hyperplasia.
D006801:Humans; D006942:Hypergammaglobulinemia / Q000503:physiopathology*; D007070:Immunoglobulin A / Q000378:metabolism*; D007145:Immunoglobulin kappa-Chains; D007146:Immunoglobulin lambda-Chains; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications / Q000503:physiopathology*; D013997:Time Factors
D007070:Immunoglobulin A; D007145:Immunoglobulin kappa-Chains; D007146:Immunoglobulin lambda-Chains
Régression d'une gammapathie monoclonale à IgA kappa lors du développement d'une maladie de Kahler à IgA lambda.