title: Auditory processing deficit in a patient with Rett syndrome.
abstract: Because of the consistent and prominent language failure in Rett syndrome, a patient with the characteristic phenotype was tested for subtle auditory processing deficits by visual reinforcement audiometry. In spite of excellent detection threshold and frequency discrimination, frequency sweep discrimination was at a chance level. This discrimination is normally performed by 5-8 month old infants. This observation suggests a defect in the specialized units of the inferior colliculus or higher auditory centers which subserve frequency sweep discrimination.
mesh_terms: D001299:Audiometry; D001303:Auditory Cortex / Q000503:physiopathology; D001307:Auditory Perception / Q000502:physiology*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007245:Inferior Colliculi / Q000503:physiopathology; D008607:Intellectual Disability / Q000503:physiopathology*; D009069:Movement Disorders / Q000503:physiopathology*; D013577:Syndrome