Ontogeny of spontaneous petit mal-like seizures in Wistar rats.
Wistar rats spontaneously presenting electroclinical signs of petit mal-like epileptic seizures were inbred until all offspring were affected, and the ontogeny of this inherited phenotype was studied in the offspring from 30-60 days of age to 18 months. The first EEG spike and wave discharges appeared at 40-120 days. Their number and duration increased progressively with age.
D000375:Aging / Q000502:physiology*; D000818:Animals; D004195:Disease Models, Animal; D004569:Electroencephalography; D004832:Epilepsy, Absence / Q000235:genetics / Q000503:physiopathology*; D005260:Female; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains