title: Rheographic vascular manifestations in some rare malignant hemopathies.
abstract: The present paper is dealing with cerebral irrigation aspects in three patients with vera polycythemia and 16 with Cooley's anaemia using the non-invasive rheoencephalographic method. The rheographic exploration was done with a 4-channel I.C.E. rheograph, being recorded on a B-channel Galileo multirecorder in parallel with the mathematical derivative of the wave and an EKG lead. The analysis of the rheographic parameter revealed that in patients with vera polycythemia there is an obvious venous stasis as well as important vasomotor tonus modifications induced by an affected blood viscosity. In patients with Cooley's anaemia, modifications in the cerebral irrigation are dominated by chronic anaemia; the latter causes chronic hypoxia of the whole body and a reduced cerebral irrigation due to a depressed cardiac volume and vasomotor tonus to the effect of hypothermia--explained through cerebral vascular self-regulation mechanisms. The investigated groups are interesting because their diseases are rare and severe; their cardiac performance was severely affected, with severe hemodynamic disturbances in the cerebral circulation, too.
mesh_terms: D002560:Cerebrovascular Circulation; D002908:Chronic Disease; D006439:Hemodynamics; D006801:Humans; D002534:Hypoxia, Brain / Q000503:physiopathology; D010992:Plethysmography, Impedance; D011087:Polycythemia Vera / Q000503:physiopathology*; D013789:Thalassemia / Q000503:physiopathology*