Effect of amiloride on the intracellular sodium and potassium content of intact Streptococcus faecalis cells in vitro.
Amiloride at millimolar concentrations caused marked changes in the growth-dependent intracellular balance of Na+ and K+ in Streptococcus faecalis. These results, whether specific to transport processes or resulting from indirect yet unknown mechanisms, constitute the first evidence of an effect of amiloride on bacterial electrolytes.
D000584:Amiloride / Q000494:pharmacology*; D013293:Enterococcus faecalis / Q000187:drug effects / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D011188:Potassium / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism*
D000584:Amiloride; D012964:Sodium; D011188:Potassium