In vitro oxidation of the 8-hydroxyquinoline moiety with metabolic activation system to a mutagenic quinoloquinone compound of lavendamycin analogs.
D000818:Animals; D001711:Biotransformation; D006912:Hydroxyquinolines / Q000378:metabolism*; D008297:Male; D051379:Mice; D009153:Mutagens / Q000378:metabolism*; D010084:Oxidation-Reduction; D015125:Oxyquinoline / Q000378:metabolism*; D013308:Streptonigrin / Q000031:analogs & derivatives* / Q000378:metabolism
D006912:Hydroxyquinolines; D009153:Mutagens; D013308:Streptonigrin; D015125:Oxyquinoline; C034566:lavendamycin