title: [Infections with penicillinase-producing Neisseria gonorrhoeae in females. Report on 24 cases].
abstract: Between the last few weeks of 1980 and March 1985 the susceptibilities of 881 strains of Neisseria gonorrhoeae to penicillin were tested by a simple screening method (disc diffusion test). 76.6% of the isolates were good susceptible, 17.7% moderately susceptible and 5.7% resistant to 3 units of penicillin G. Penicillinase-producing Neisseria gonorrhoeae (PPNG) could be detected in 24 cases (2.7%), most of them between July 1983 and January 1984 (n = 18). 23 patients have been treated successfully with oxytetracycline. All infections had been acquired in the GDR, however, the sources of infection could be firmly traced in 6 cases only. On the basis of the results some clinical and microbiological aspects of infections with penicillin resistant gonococci are discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D004305:Dose-Response Relationship, Drug; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D009344:Neisseria gonorrhoeae / Q000187:drug effects* / Q000201:enzymology; D010400:Penicillin G / Q000627:therapeutic use*; D010403:Penicillin Resistance; D010405:Penicillinase / Q000378:metabolism*
chemical_list: D010405:Penicillinase; D010400:Penicillin G
vernacular_title: Infektionen mit Penicillinase produzierenden Neisseria gonorrhoeae bei Frauen. Bericht über 24 Fälle.