[Predatory aggressiveness of the rat after intraventricular administration of individual brain-specific proteins of the S-100 group and their peptide fragments].
Intraventricular injections to rats of the basic fraction of the brain specific protein S-100 in a concentration of 3 mg/ml, significantly facilitates the formation of their predatory aggression induced by the alimentary deprivation and social isolation, expressed in mice killing. This effect is not produced by fragments of S-100 molecules obtained as a result of treatment of the basic protein fraction by proteolytic enzymes. Administration of the minor S-100 fraction, albumin and rats summate brain proteins did not influence animals predatory aggression.
D000374:Aggression / Q000187:drug effects*; D000818:Animals; D001070:Appetitive Behavior / Q000187:drug effects*; D001921:Brain / Q000187:drug effects; D002384:Catalysis; D007276:Injections, Intraventricular; D008297:Male; D010434:Pepsin A; D010446:Peptide Fragments / Q000494:pharmacology*; D011235:Predatory Behavior / Q000187:drug effects*; D011402:Pronase; D051381:Rats; D009418:S100 Proteins / Q000494:pharmacology*; D014357:Trypsin
D010446:Peptide Fragments; D009418:S100 Proteins; D014357:Trypsin; D010434:Pepsin A; D011402:Pronase
Khishchnicheskaia agressivnost' krys posle vnutrizheludochkovogo vvedeniia otdel'nykh mozgospetsificheskikh belkov gruppy S-100 i ikh peptidnykh fragmentov.