title: Formation of a cyclic adenine adduct with a 4-nitroquinoline N-oxide metabolite model.
abstract: Pentacyclic adducts are obtained in the reaction of adenine derivatives with the diacetyl ester of 4-hydroxyamino quinoline oxide, the postulated metabolite of the potent carcinogen, 4-nitroquinoline N-oxide (4-NQO).
mesh_terms: D015112:4-Nitroquinoline-1-oxide / Q000031:analogs & derivatives*; D000225:Adenine / Q000031:analogs & derivatives*; D055598:Chemical Phenomena; D002621:Chemistry; D004249:DNA Damage; D009600:Nitroquinolines
chemical_list: D009600:Nitroquinolines; D015112:4-Nitroquinoline-1-oxide; D000225:Adenine