Identification of t-PA as the major active plasminogen activator in human milk.
Human colostrum and milk contain high levels of plasminogen activator when compared with blood. These levels are inversely related to the duration of lactation and the activity appears to be due to tissue type plasminogen activator present in multiple (65-190 Kd) molecular weight forms.
D000906:Antibodies / Q000276:immunology; D003126:Colostrum / Q000032:analysis; D004587:Electrophoresis, Agar Gel / Q000379:methods; D005260:Female; D006801:Humans; D008895:Milk, Human / Q000032:analysis*; D008970:Molecular Weight; D010960:Plasminogen Activators / Q000032:analysis; D011247:Pregnancy; D013997:Time Factors; D010959:Tissue Plasminogen Activator / Q000032:analysis / Q000276:immunology / Q000302:isolation & purification*
D000906:Antibodies; D010960:Plasminogen Activators; D010959:Tissue Plasminogen Activator