[Immunotoxicotherapy: protective effect of anti-colchicine antibodies in acute colchicine poisoning in rabbits and mice].
Anti-colchicine antibodies are able to neutralize toxic effects of colchicine after acute intoxication in rabbits and mice. The protecting effect is demonstrated by active immunization (rabbits) or passive immunization (mice). These data suggest that the immunotoxicotherapy may be useful for compounds (colchicine) with intracellular action.
D000818:Animals; D000906:Antibodies / Q000008:administration & dosage*; D003078:Colchicine / Q000276:immunology / Q000506:poisoning*; D007114:Immunization; D007116:Immunization, Passive; D007074:Immunoglobulin G / Q000627:therapeutic use; D008297:Male; D051379:Mice; D011817:Rabbits
D000906:Antibodies; D007074:Immunoglobulin G; D003078:Colchicine
Immunotoxicothérapie: effet protecteur d'anticorps anticolchicine lors de l'intoxication aiguë à la colchicine chez le lapin et la souris.