Severe aplastic anaemia following hepatitis A.
A 3-year-old child developed severe aplastic anaemia following hepatitis A. Since no HLA-compatible donor was available, he was treated with oxymetholone, antithymocytic globulin and methylprednisolone, but no haematologic recovery was observed and he consequently died of pneumonia. Although the association of aplastic anaemia and hepatitis A has already been recognized, this patient represents the first case of aplastic anaemia in which the previous hepatitis A has been well documented.
D000741:Anemia, Aplastic / Q000209:etiology* / Q000628:therapy; D002675:Child, Preschool; D006506:Hepatitis A / Q000150:complications*; D006801:Humans; D008297:Male