Metabolism of non-enzymic glycosylated low density lipoprotein by mini pig aortic endothelial cells.
[U-14C]-glucose was incorporated non-enzymatically into the protein moiety of human low density lipoprotein. The incorporation was time and glucose concentration dependent. Investigated mini pig aortic endothelial cells showed that the glycosylated low density lipoprotein was bound, internalized and degraded significantly less than that of the native one measured with [125-I]-low density lipoprotein.
D000818:Animals; D001011:Aorta / Q000378:metabolism*; D001665:Binding Sites; D002478:Cells, Cultured; D004727:Endothelium / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D017127:Glycation End Products, Advanced; D007700:Kinetics; D008077:Lipoproteins, LDL / Q000378:metabolism*; D013552:Swine; D013556:Swine, Miniature; D000093844:Glycated Proteins
D005947:Glucose; D017127:Glycation End Products, Advanced; D008077:Lipoproteins, LDL; C031797:glycated lipoproteins, LDL; D000093844:Glycated Proteins