title: Bile pigments inhibit microsomal lipid peroxidation.
abstract: Bile pigments (bilirubin and biliverdin) inhibit lipid peroxidation in rat liver microsomes at physiological concentrations. Since an alternative course for bilirubin degradation involving superoxide radical has been described, a possible explanation of the decrease of the initial rate of lipid peroxidation could be the scavenging of .O2-.
mesh_terms: D000818:Animals; D001663:Bilirubin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D001664:Biliverdine / Q000494:pharmacology*; D007700:Kinetics; D008054:Lipid Peroxides / Q000037:antagonists & inhibitors*; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D009249:NADP / Q000378:metabolism; D051381:Rats
chemical_list: D008054:Lipid Peroxides; D009249:NADP; D001664:Biliverdine; D001663:Bilirubin