title: The gene encoding the mouse T cell differentiation antigen L3T4 is located on chromosome 6.
abstract: We have used Southern blot analysis of DNA from somatic cell hybrids to map the chromosomal location of the mouse L3T4 T cell differentiation antigen gene to chromosome 6. This finding is of interest because both L3T4 and the alternative T cell differentiation antigen Lyt-2 are homologous to kappa-immunoglobulin light chain-variable regions, and the genes encoding kappa and Lyt-2 are also located on mouse chromosome 6.
mesh_terms: D000818:Animals; D000945:Antigens, Differentiation, T-Lymphocyte; D000954:Antigens, Surface / Q000235:genetics*; D002874:Chromosome Mapping; D005796:Genes; D008040:Genetic Linkage; D051379:Mice; D005810:Multigene Family
chemical_list: D000945:Antigens, Differentiation, T-Lymphocyte; D000954:Antigens, Surface