Haptoglobin type in connection with mean age at first breast cancer signs?
In breast cancer patients divided into groups according to haptoglobin (Hp) type (519 patients), blood group (ABO) (433 patients) or Rh factor (358 patients) the mean age at first disease manifestation was calculated. The results indicate that in Hp 1 bearers breast cancer appears at significantly lower age (49 years) as compared to Hp type 2-1 (53.3 years) or Hp 2 (53 years). In blood groups the mean age at first cancer signs raises from 48 years in the AB group to 53.1 years in the A group, only the difference between A and AB being significant. However, these preliminary results require confirmation in larger patient series.
D000017:ABO Blood-Group System; D000328:Adult; D000367:Age Factors; D001943:Breast Neoplasms / Q000276:immunology*; D006242:Haptoglobins / Q000032:analysis*; D006801:Humans; D008875:Middle Aged; D012204:Rh-Hr Blood-Group System
D000017:ABO Blood-Group System; D006242:Haptoglobins; D012204:Rh-Hr Blood-Group System