[Does sex hormone balance modify the pathogenesis of laryngeal cancer?].
Although there are some pointers towards dependence of pathogenesis of laryngeal cancer on hormone metabolism, proof for this assumption is still missing. We studied hormone metabolism of 43 patients with laryngeal disease (testosterone, oestradiol, FSH, LH, prolactin). We subdivided the patients into two groups: 20 patients with squamous cell carcinoma and 23 patients with non-malignant diseases. No differences were seen between the two groups on statistical evaluation of the data. We could not prove any hormonal dependence, which might have had a therapeutical impact on the administration of antiandrogen drugs.
D002294:Carcinoma, Squamous Cell / Q000097:blood / Q000209:etiology*; D004958:Estradiol / Q000097:blood*; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007822:Laryngeal Neoplasms / Q000097:blood / Q000209:etiology*; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008875:Middle Aged; D009376:Neoplasms, Hormone-Dependent / Q000097:blood*; D011388:Prolactin / Q000097:blood; D013739:Testosterone / Q000097:blood*
D013739:Testosterone; D004958:Estradiol; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
Beeinflusst der Sexualhormonhaushalt die Pathogenese von Larynxkarzinomen?