Double-blind comparison of the protective effect of sodium cromoglycate and ketotifen on exercise-induced asthma in adults.
In a double-blind double-placebo study 10 asthmatics exercised on a treadmill after treatment for 1 week with placebo, or ketotifen 1 mg twice daily, or SCG 10 mg four times daily. The post-exercise percentage fall in FEV1 after SCG but not after ketotifen was significantly smaller than after placebo. A 1-week treatment with SCG but not ketotifen protected against EIA.
D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000517:prevention & control*; D001250:Asthma, Exercise-Induced / Q000188:drug therapy / Q000503:physiopathology / Q000517:prevention & control*; D004205:Cromolyn Sodium / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D007665:Ketotifen / Q000627:therapeutic use*; D008297:Male; D005082:Physical Exertion; D011897:Random Allocation
D004205:Cromolyn Sodium; D007665:Ketotifen