Secondary refractory anemia with excess of blasts in transformation terminating as acute lymphoblastic leukemia.
A case of refractory anemia with an excess of blasts in transformation, secondary to irradiation, and leading ultimately to acute lymphoblastic leukemia, is presented. Commonalities and differences between acute lymphoblastic and nonlymphoblastic leukemias secondary to radiotherapy are discussed.
D000368:Aged; D000369:Aged, 80 and over; D000754:Anemia, Refractory, with Excess of Blasts / Q000150:complications*; D002454:Cell Differentiation; D006801:Humans; D007945:Leukemia, Lymphoid / Q000209:etiology*; D008297:Male; D014411:Neoplastic Stem Cells / Q000473:pathology