Multiple myeloma with serum IgM kappa and Bence Jones lambda biclonal gammopathy.
We report a rare finding: IgM kappa and Bence Jones lambda double gammopathy in serum of a 80-year-old man with untreated symptomatic multiple myeloma. The unusual findings are confined to the laboratory studies demonstrating also a Bence Jones lambda proteinuria, high erythrocyte sedimentation rate (113 mm/h), and anemia. The synthesis of the different light chains seems to occur in separate cellular clones.
D000368:Aged; D000369:Aged, 80 and over; D001536:Bence Jones Protein / Q000032:analysis*; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications*; D007075:Immunoglobulin M / Q000032:analysis*; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D008297:Male; D009101:Multiple Myeloma / Q000150:complications / Q000276:immunology*
D007075:Immunoglobulin M; D007145:Immunoglobulin kappa-Chains; D001536:Bence Jones Protein