[Monitoring sodium valproate treatment of epilepsy in the development years].
The levels of sodium valproate were determined in the blood and saliva of children treated for epilepsy. The determination of drug in saliva may be a simple test checking whether the patient is taking the drugs systematically, and makes possible determination of the approximate level in the serum without blood sampling. In doubtful cases poorly responding to treatment serial monitoring of valproic acid should be undertaken.
D000293:Adolescent; D001682:Biological Availability; D002648:Child; D002675:Child, Preschool; D002940:Circadian Rhythm; D004827:Epilepsy / Q000188:drug therapy*; D006801:Humans; D008991:Monitoring, Physiologic; D012463:Saliva / Q000378:metabolism; D014635:Valproic Acid / Q000378:metabolism / Q000627:therapeutic use*
D014635:Valproic Acid
Walproinian sodu w leczeniu monitorowanym padaczki wieku rozwojowego.