Genotoxicity of mycotoxins.
Mycotoxins with their diversified structures have been a class of good model compounds, or a good tool, for evaluating the usefulness of short-term genotoxicity tests and for elucidating the mechanism of mutagenicity and carcinogenicity. Despite the limitations of these tests in predicting carcinogenicity, the genotoxicity of mycotoxins as shown by the results of a battery of genotoxicity tests indicates that mycotoxins are indeed a class of significant naturally occurring environmental carcinogens which warrant rigorous regulatory actions.
D016604:Aflatoxin B1; D000348:Aflatoxins / Q000633:toxicity; D000818:Animals; D001665:Binding Sites; D004247:DNA / Q000187:drug effects* / Q000378:metabolism; D006147:Guanine / Q000378:metabolism; D009152:Mutagenicity Tests; D009183:Mycotoxins / Q000633:toxicity*
D000348:Aflatoxins; D009183:Mycotoxins; D006147:Guanine; D004247:DNA; D016604:Aflatoxin B1