[Comparative efficiency of infecting laboratory animals via intravenous and subcutaneous administration of Schistosoma mansoni cercaria].
Comparative study on effectiveness of intravenous and subcutaneous methods of infection of animals has shown that infection rate of helminths after the injection of equal dozes of cercariae under skin, into portal and femoral veins of golden hamsters does not differ significantly (42.6 +/- 4.2, 37.8 +/- 5.8 and 26.0 +/- 6.6 schistosomes, respectively). When using the above methods for cotton rats the infection rate was lower than that in golden hamsters. The most insignificant infection rate of parasites was recorded in both species after the injection of cercariae into the femoral vein. Results of the infection of golden hamsters with different dozes of cercariae have shown that with the increase of dozes of infectious material the infection rate of helminths rises during the experimental intestinal schistosomiasis only to a definite level, which is attained by the injection of cercariae into the portal vein in dozes lower than those used for subcutaneous infection.
D000818:Animals; D003411:Arvicolinae; D006224:Cricetinae; D004195:Disease Models, Animal; D004198:Disease Susceptibility; D007275:Injections, Intravenous; D007279:Injections, Subcutaneous; D007814:Larva / Q000472:pathogenicity; D008647:Mesocricetus; D012550:Schistosoma mansoni / Q000472:pathogenicity*; D012555:Schistosomiasis mansoni / Q000469:parasitology*; D013997:Time Factors
Sravnitel'naia éffektivnost' zarazheniia laboratornykh zhivotnykh pri vnutrivennom i podkozhnom vvedenii tserkariĭ Schistosoma mansoni.