title: Cardiac arrhythmias in the elderly: antiarrhythmic drug treatment.
abstract: The frequency of ventricular arrhythmias increases with age. Several factors make elderly people more prone to antiarrhythmic drug toxicity. Familiarity with the changes in the pharmacokinetics and pharmacodynamics of antiarrhythmic agents may reduce or prevent adverse response in this patient population.
mesh_terms: D000368:Aged; D000638:Amiodarone / Q000627:therapeutic use; D000813:Anilides / Q000627:therapeutic use; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000188:drug therapy*; D001949:Bretylium Compounds / Q000627:therapeutic use; D004077:Digoxin / Q000627:therapeutic use; D004206:Disopyramide / Q000627:therapeutic use; D016700:Encainide; D005424:Flecainide; D006801:Humans; D008012:Lidocaine / Q000031:analogs & derivatives / Q000627:therapeutic use; D008801:Mexiletine / Q000627:therapeutic use; D010880:Piperidines / Q000627:therapeutic use; D011342:Procainamide / Q000627:therapeutic use; D011433:Propranolol / Q000627:therapeutic use; D011802:Quinidine / Q000627:therapeutic use; D016677:Tocainide; D014700:Verapamil / Q000627:therapeutic use
chemical_list: D000813:Anilides; D000889:Anti-Arrhythmia Agents; D001949:Bretylium Compounds; D010880:Piperidines; D008801:Mexiletine; D016677:Tocainide; D004077:Digoxin; D008012:Lidocaine; D011433:Propranolol; D014700:Verapamil; D004206:Disopyramide; D011802:Quinidine; D005424:Flecainide; D011342:Procainamide; D000638:Amiodarone; C045166:bretylium; D016700:Encainide