Sarcoidosis and immunocytoma.
The current literature contains reports of sarcoidosis with polyclonal increases in immunoglobulins. There are also reports of lymphoma in patients with pre-existing sarcoidosis. This is believed to be the first report of a patient in whom a monoclonal IgM kappa paraproteinemia developed after the diagnosis of sarcoidosis. This paraproteinemia was linked with a histologically proved non-Hodgkin's lymphoma. The possible relationships between the two disease entities are discussed.
D001706:Biopsy; D006099:Granuloma / Q000473:pathology; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D008171:Lung Diseases / Q000150:complications / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology; D008223:Lymphoma / Q000150:complications / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010265:Paraproteinemias / Q000209:etiology / Q000473:pathology; D012507:Sarcoidosis / Q000150:complications / Q000473:pathology*
D007145:Immunoglobulin kappa-Chains