title: [Chronoavailability: a theoretical method of studying chronopharmacology].
abstract: The optimum time of drug administration or the chronestesy of a biosystem can be theoretically determined by the integration of the function: (drug concentration)-(susceptibility of the biosystem) versus time. This integral called chronoavailability could be useful to design experiments for evaluation of chronopharmacologic effects in man.
mesh_terms: D001682:Biological Availability; D006801:Humans; D007700:Kinetics; D008433:Mathematics; D008954:Models, Biological; D010507:Periodicity; D004364:Pharmaceutical Preparations / Q000378:metabolism*
chemical_list: D004364:Pharmaceutical Preparations
vernacular_title: Chronodisponibilité: une méthode théorique d'étude de la chronopharmacologie.