[Effect of acid extraction on the osteogenic activity of bone tissue].
Rat bones demineralized in HCl and TCA exhibited distinct osteoinductive activity while the bones demineralized using EDTA did not show the activity. HCl- and TCA-extracts of bones differed from EDTA extracts by chromatographic and radiochromatographic profiles. At the same time, HCl- and TCA-extracts contained additional fraction. The substances involved in the fraction appear to be responsible for inhibition of the osteoinductive factor of bone tissue.
D000818:Animals; D001857:Bone Matrix / Q000032:analysis / Q000502:physiology*; D001861:Bone Regeneration; D016025:Bone Transplantation; D004492:Edetic Acid; D006851:Hydrochloric Acid; D008903:Minerals / Q000032:analysis*; D051381:Rats; D014020:Tissue Extracts / Q000032:analysis; D014238:Trichloroacetic Acid
D008903:Minerals; D014020:Tissue Extracts; D014238:Trichloroacetic Acid; D004492:Edetic Acid; D006851:Hydrochloric Acid
Vliianie kislotnoĭ ékstraktsii na osteoinduktivnuiu aktivnost' kostnoĭ tkani.