[Non-specific antitumoral activity of staphylococcal enterotoxins].
St. aureus enterotoxins A and B possess an antitumour effect. After intraperitoneal inoculation they decrease the size and in some cases prevent the development of the human hypernephroma in the cheek pouch of golden hamsters. The effect of enterotoxins may possibly consist in inducing the production of endogenous immune interferon which activates the host immune system and enhances the rejection of heterologous tumour cells.
D000818:Animals; D002292:Carcinoma, Renal Cell / Q000276:immunology / Q000628:therapy*; D002478:Cells, Cultured; D006224:Cricetinae; D004768:Enterotoxins / Q000627:therapeutic use*; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use; D007371:Interferon-gamma / Q000627:therapeutic use; D007680:Kidney Neoplasms / Q000276:immunology / Q000628:therapy*; D008647:Mesocricetus; D009368:Neoplasm Transplantation; D013211:Staphylococcus aureus
D004768:Enterotoxins; D007370:Interferon Type I; C026066:enterotoxin A, Staphylococcal; C031818:enterotoxin B, staphylococcal; D007371:Interferon-gamma
Protivoopukholevaia nespetsificheskaia aktivnost' stafilokokkovykh énterotoksinov.