[Scanning electron microscopic method for studying the interaction of normal peritoneal macrophages with tumor cells].
It is shown that the damage action of normal peritoneal macrophages of mice includes inhibition of the proliferating activity of the mastocytoma P-815 cells and their complete destruction accompanied by the breaks of their cytoplasmic membrane. Scanning electron microscopy was used to reveal two types of contacts between peritoneal macrophages and cells P-815; the loss of microvilli and the appearance of blebs on cell surface in the case of adsorption of P-815 cells on macrophages; the contact through long filopodia which are sent forth by macrophages in the case when contacting cells are at some distance from each other.
D000818:Animals; D002450:Cell Communication; D002469:Cell Separation; D002478:Cells, Cultured; D003602:Cytotoxicity, Immunologic; D008264:Macrophages / Q000276:immunology / Q000648:ultrastructure*; D008297:Male; D012515:Mast-Cell Sarcoma / Q000276:immunology / Q000648:ultrastructure*; D051379:Mice; D008807:Mice, Inbred BALB C; D008855:Microscopy, Electron, Scanning / Q000379:methods; D010529:Peritoneal Cavity / Q000648:ultrastructure*
Izuchenie metodom skaniruiushcheĭ élektronnoĭ mikroskopii vzaimodeĭstviia normal'nykh peritoneal'nykh makrofagov s opukholevymi kletkami.