Synthesis and some reactions of 2-cyanomethylimidazo [4,5-b]pyridine. Tuberculostatic investigations of obtained compounds.
2-Cyanomethylimidazo [4,5-b]pyridine 1 was obtained and its properties during acid and basic hydrolysis, esterification, and reaction with hydrogen sulfide were investigated. Condensation of 1 with aromatic aldehydes was also studied. Some of the obtained compounds were tested on tuberculostatic activity.
D000995:Antitubercular Agents / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D007093:Imidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D011725:Pyridines / Q000138:chemical synthesis* / Q000494:pharmacology
D000995:Antitubercular Agents; D007093:Imidazoles; D011725:Pyridines; C049691:2-cyanomethylimidazo(4,5-b)pyridine