title: DNA sequence adjacent to and specific for the 1.672 g/cm3 satellite DNA in the Drosophila genome.
abstract: The Drosophila genome contains nearly 2.8 X 10(4) kilobases of satellite DNA. This simple sequence satellite DNA is contained within transcriptionally inactive heterochromatin that is distributed among all chromosomes with a concentration at the centromeres and along the length of the Y chromosome. To investigate the relationship of the satellite DNA with the surrounding sequences, we have isolated a satellite junction sequence that is repetitive and specifically adjacent to the 1.672 g/cm3 satellite DNA. It is conserved between strains of Drosophila melanogaster and localized to the chromocenter of polytene chromosomes. The characteristics of this sequence suggest a functional role involving the specific organization of large regions of chromosomes.
mesh_terms: D000818:Animals; D001483:Base Sequence; D002843:Chromatin; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D004276:DNA, Satellite; D004331:Drosophila melanogaster / Q000235:genetics*; D022041:Euchromatin; D006570:Heterochromatin / Q000648:ultrastructure*; D009693:Nucleic Acid Hybridization; D012091:Repetitive Sequences, Nucleic Acid
chemical_list: D002843:Chromatin; D004276:DNA, Satellite; D022041:Euchromatin; D006570:Heterochromatin