title: Digoxin effect and imprinting in the unicellular Tetrahymena.
abstract: Treatment with digoxin increased, whereas treatment with ouabain decreased, the growth rate of Tetrahymena, but the progeny generations showed an increased mitotic rate after both treatments. A single exposure to digoxin or ouabain accounted for a more than twofold increase in the incorporation (binding) of the cardiac glycosides in the progeny generations.
mesh_terms: D001345:Autoradiography; D004077:Digoxin / Q000378:metabolism / Q000494:pharmacology*; D010042:Ouabain / Q000494:pharmacology; D013769:Tetrahymena pyriformis / Q000187:drug effects* / Q000502:physiology
chemical_list: D010042:Ouabain; D004077:Digoxin