[Correction of neutropenia with lithium carbonate during the radiation treatment of lymphogranulomatosis patients].
The purpose of the investigation was to study the effect of lithium carbonate on the time-course of changes in neutrophil leukocytes of the peripheral blood. Sixty-nine patients afflicted with Hodgkin's disease were entered into the study. Greater preservation of the content of neutrophil leukocytes was attained with the use of lithium carbonate coupled with radiation therapy. At the same time administration of lithium carbonate in the interval between the stages of anticancer treatment brought about an increase in the neutrophil count.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000380:Agranulocytosis / Q000188:drug therapy*; D003131:Combined Modality Therapy; D004341:Drug Evaluation; D005260:Female; D006689:Hodgkin Disease / Q000150:complications* / Q000532:radiotherapy; D006801:Humans; D007958:Leukocyte Count / Q000528:radiation effects; D008094:Lithium / Q000627:therapeutic use*; D016651:Lithium Carbonate; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000188:drug therapy* / Q000209:etiology; D009504:Neutrophils / Q000528:radiation effects; D011879:Radiotherapy Dosage
D016651:Lithium Carbonate; D008094:Lithium
Korrektsiia neĭtropenii karbonatom litiia pri luchevom lechenii bol'nykh limfogranulematozom.