title: CO2 challenge of patients with panic disorder.
abstract: In an open trial, five of eight panic disorder patients and none of five control subjects panicked after inhalation of two breaths of 35% CO2 and 65% O2; none panicked after placebo. Using 35% CO2 to induce panic is safe, simple, and well tolerated and may provide a valuable laboratory model of panic.
mesh_terms: D000280:Administration, Inhalation; D000328:Adult; D001008:Anxiety Disorders / Q000139:chemically induced* / Q000175:diagnosis; D002245:Carbon Dioxide / Q000008:administration & dosage; D005239:Fear; D006801:Humans; D010100:Oxygen / Q000008:administration & dosage; D010200:Panic; D010865:Pilot Projects
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen