Pyridoxine: a potential local antidote for Mitomycin-C extravasation.
Two cases are presented which suggest that pyridoxine injected into a Mitomycin-C extravasation site may slow or prevent necrosis, and may decrease the pain associated with the chronic ulceration of extravasation.
D000368:Aged; D000931:Antidotes; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D016685:Mitomycin; D008937:Mitomycins / Q000009:adverse effects*; D011736:Pyridoxine / Q000008:administration & dosage*
D000931:Antidotes; D008937:Mitomycins; D016685:Mitomycin; D011736:Pyridoxine