The role of hepatic lectins and the activity of the mononuclear phagocyte system in systemic Listeria monocytogenes infection in Balb/c mice.
Hepatic lectin blocking experiments with D-galactose in Balb/c mice showed that parenchymal liver cells are obviously not involved in Listeria monocytogenes infection (strain SLCC 4013, 5 X 10(6) cells i.v.). Using the bacterial immunomodifier Propionibacterium avidum KP-40 the importance of an activated mononuclear phagocyte system in the early stage of Listeria infection could be demonstrated.
D000276:Adjuvants, Immunologic / Q000494:pharmacology; D000818:Animals; D037263:Asialoglycoprotein Receptor; D005690:Galactose / Q000494:pharmacology; D008089:Listeria monocytogenes; D008088:Listeriosis / Q000209:etiology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D010586:Phagocytes / Q000276:immunology*; D011424:Propionibacterium / Q000276:immunology; D011971:Receptors, Immunologic / Q000187:drug effects / Q000276:immunology*
D000276:Adjuvants, Immunologic; D037263:Asialoglycoprotein Receptor; D011971:Receptors, Immunologic; D005690:Galactose