Indomethacin: an adjunct to surgical excision of immature heterotopic bone formation in a patient with a severe head injury. A case report.
This case reports heterotopic ossification which produced ankylosis around the hip joint in a young adult treated with steroids for moderate cognitive defects secondary to brain trauma. It is associated with a high recurrence rate, especially if the bone is immature. The patient's heterotopic bone was surgically excised nine months post-injury, augmented with six weeks of indomethacin, and followed for three years.
D000328:Adult; D001842:Bone and Bones; D002543:Cerebral Hemorrhage / Q000150:complications*; D002828:Choristoma / Q000188:drug therapy* / Q000209:etiology / Q000601:surgery; D006617:Hip Dislocation / Q000150:complications*; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use*; D008297:Male; D009135:Muscular Diseases / Q000188:drug therapy* / Q000209:etiology / Q000601:surgery; D009369:Neoplasms / Q000188:drug therapy / Q000209:etiology / Q000601:surgery; D009999:Ossification, Heterotopic / Q000188:drug therapy*
D007213:Indomethacin