title: Recombinant murine gamma interferon inhibits Chlamydia trachomatis serovar L1 in vivo.
abstract: Chlamydia trachomatis serovar L1 injected intravenously in mice resulted in systemic nonlethal infections of the animals. Treatment of mice with recombinant murine gamma interferon resulted in a decrease in the number of infectious C. trachomatis organisms recovered from the lungs, spleens, and livers as well as in a decrease of the inflammatory reaction in those organs when assessed 3 and 5 days after challenge.
mesh_terms: D000818:Animals; D002690:Chlamydia Infections / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D002692:Chlamydia trachomatis / Q000254:growth & development*; D005260:Female; D007371:Interferon-gamma / Q000494:pharmacology*; D008099:Liver / Q000382:microbiology / Q000473:pathology; D051379:Mice; D008807:Mice, Inbred BALB C; D011994:Recombinant Proteins / Q000494:pharmacology*
chemical_list: D011994:Recombinant Proteins; D007371:Interferon-gamma