Baclofen responsive posttraumatic epilepsy.
A 21-year-old man with posttraumatic epilepsy was poorly controlled on conventional anticonvulsant agents (phenytoin, carbamazepine). However, co-administration of the GABA mimetic agent baclofen improved significantly his seizure control, suggesting that the latter agent could be useful in the management of refractory epilepsy.
D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage / Q000627:therapeutic use; D001418:Baclofen / Q000008:administration & dosage / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004834:Epilepsy, Post-Traumatic / Q000188:drug therapy*; D006801:Humans; D008297:Male
D000927:Anticonvulsants; D001418:Baclofen