title: Valorization of rapeseed meal. 5. Effects of sinapine and other phenolic compounds on food intake and nutrient utilization in growing rats.
abstract: Six groups of 10 growing rats each were fed ad libitum for 15 days one of six diets: diet A, rapeseed (3.80 g of sinapine/kg DM); diet B, ethanol/water-extracted rapeseed (0.48 g of sinapine); diet C, control diet; diet G, control diet + 3.74 g of extracted sinapine; diet H, control diet + 3.72 g of sinapine + other phenolic compounds; or diet I, control diet + the hydrolysis products of sinapine and other phenolic compounds. During the first 8 days, the dry matter intake and live weight gain of the rats were significantly reduced by the intake of sinapine and other phenolic compounds. However, after this adaptation period their performances were similar to those of the control group. Dry matter, energy and nitrogen digestibility and protein utilization were not altered by sinapine intake but were slightly reduced with diets H and I.
mesh_terms: D000818:Animals; D001066:Appetite / Q000187:drug effects*; D001835:Body Weight / Q000187:drug effects; D001937:Brassica; D002794:Choline / Q000031:analogs & derivatives* / Q000494:pharmacology; D005527:Food, Fortified; D008239:Lysine / Q000494:pharmacology; D008297:Male; D010636:Phenols / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains / Q000254:growth & development*
chemical_list: D010636:Phenols; C005685:sinapine; D008239:Lysine; D002794:Choline