title: [A comparison of the diagnostic reliability of the results of isotopic and routine clearance studies in essential and symptomatic hypertension].
abstract: 40 patients with arterial hypertension II stage, 51 patients with chronic pyelonephritis and glomerulonephritis and a control group of IO healthy persons were examined during a free from medicamentous treatment period by a group of clearance tests in order to study the excretory system function and the degree of its affection in the earliest phases of the diseases studied. By means of the isotopic clearances of 169Yb-EDTA for determinations of the glomerular filtration, 131-I-hippuran for effective renal plasma circulation, the electrolytic clearances of Na, K, Ca, Cl and creatinine, the volume of the water excretion and the lithium clearance, the degree of the renal lesion was determined in every patient examined by the deviations from the normal values and the role of the different nephron sections as well. The results of the study revealed that the best tests for evaluation of the renal function in chronic renal diseases are the electrolyte clearances of Na, K, Ca, Cl, and in arterial hypertension--the lithium clearance.
mesh_terms: D002908:Chronic Disease; D004492:Edetic Acid; D004573:Electrolytes / Q000378:metabolism; D005069:Evaluation Studies as Topic; D006801:Humans; D006973:Hypertension / Q000000981:diagnostic imaging* / Q000378:metabolism; D007465:Iodohippuric Acid; D007674:Kidney Diseases / Q000000981:diagnostic imaging / Q000378:metabolism; D008094:Lithium; D016651:Lithium Carbonate; D008657:Metabolic Clearance Rate; D011866:Radioisotope Renography; D011868:Radioisotopes; D015018:Ytterbium
chemical_list: D004573:Electrolytes; D011868:Radioisotopes; D007465:Iodohippuric Acid; D016651:Lithium Carbonate; D008094:Lithium; D004492:Edetic Acid; D015018:Ytterbium
vernacular_title: Sŭpostavka na diagnostichnata nadezhnost na rezultatite ot izotopnite i niakoi rutinni klirŭnsovi prouchvaniia pri esentsialna i simptomatichna khipertoniia.