Aurothioglucose overdosage in five patients with rheumatoid arthritis.
Five patients with active seronegative, rheumatoid arthritis, HLA-DR3 negative, received inadvertently 250 to 500 mg of aurothioglucose instead of their usual weekly dose, during standard remission-inducing chrysotherapy. Subsequently a rapid and sustained clinical remission appeared in all five patients.
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D006051:Aurothioglucose / Q000008:administration & dosage / Q000506:poisoning*; D004334:Drug Administration Schedule; D005260:Female; D006046:Gold / Q000506:poisoning*; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008508:Medication Errors; D008875:Middle Aged; D012074:Remission Induction
D006051:Aurothioglucose; D006046:Gold