Oligoclonal IgG bands in cerebrospinal fluid and serum during asymptomatic human immunodeficiency virus infection.
Serum and cerebrospinal fluid (CSF) samples from asymptomatic patients seropositive for human immunodeficiency virus (HIV) showed frequent evidence of intrathecal IgG synthesis and oligoclonal IgG bands, with different isoelectric focusing patterns in serum and CSF; 2 of 7 had a CSF pleocytosis. The results suggest frequent, early, chronic central nervous system infection following HIV infection.
D000163:Acquired Immunodeficiency Syndrome / Q000097:blood / Q000134:cerebrospinal fluid / Q000276:immunology*; D000328:Adult; D005260:Female; D006801:Humans; D007143:Immunoglobulin Heavy Chains / Q000134:cerebrospinal fluid*; D007142:Immunoglobulin gamma-Chains / Q000097:blood / Q000134:cerebrospinal fluid*; D007525:Isoelectric Focusing; D008297:Male
D007143:Immunoglobulin Heavy Chains; D007142:Immunoglobulin gamma-Chains