title: [Lithium poisoning with persistent neurological sequelae].
abstract: A patient suffering from manic-depressive illness was treated on a long-term basis with lithium carbonate in consistent dosage. In the course of intercurrent Q-fever he developed lithium intoxication which led to a severe and, as confirmed by a follow-up examination after 5 years, irreversible cerebellar syndrome as well as a discrete organic mental syndrome. The course of the lithium intoxication itself was exceptional in this patient: the cerebellar symptoms appeared very early during the intoxication and were dissociated from any other central nervous system signs or symptoms, especially impairment of consciousness.
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000150:complications / Q000188:drug therapy*; D002524:Cerebellar Ataxia / Q000139:chemically induced*; D006801:Humans; D008094:Lithium / Q000506:poisoning* / Q000627:therapeutic use; D016651:Lithium Carbonate; D008297:Male; D011778:Q Fever / Q000150:complications; D019966:Substance-Related Disorders / Q000209:etiology*
chemical_list: D016651:Lithium Carbonate; D008094:Lithium
vernacular_title: Lithiumintoxikation mit persistierenden neurologischen Störungen.