[Cerebrorenal oxalate formation--a metabolic abnormality following parenteral infusions of carbohydrate exchange substances].
A 46 years old male alcoholic was admitted with an assumed alcohol withdrawal syndrome accompanied by tonic-clonic seizures. Parenteral nutrition with fructose, sorbitol, xylitol, dextran, hydroxyethylstarch, electrolytes, vitamins and amino acids was undertaken. He died 20 d later due to renal insufficiency and bronchopneumonia. Calcium-oxalate-monohydrate (whewellite) was found in the central nervous system, the kidneys, the testes, the epididymis, the cardiac muscle cells and the lungs. The presence of urate crystals was suspected. The pathogenesis of secondary oxalosis is discussed.
D000430:Alcohol Withdrawal Delirium / Q000628:therapy*; D001927:Brain Diseases / Q000209:etiology* / Q000473:pathology; D002129:Calcium Oxalate / Q000378:metabolism*; D005632:Fructose / Q000009:adverse effects*; D006801:Humans; D007669:Kidney Calculi / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010289:Parenteral Nutrition, Total / Q000009:adverse effects*; D011604:Psychoses, Alcoholic / Q000628:therapy*; D013012:Sorbitol / Q000009:adverse effects*; D014993:Xylitol / Q000009:adverse effects*
D002129:Calcium Oxalate; D005632:Fructose; D013012:Sorbitol; D014993:Xylitol
Zerebrorenale Oxalose--eine metabolische Entgleisung bei parenteralen Infusionen von Zuckeraustauschstoffen.