Eosinophils favor the passage of eggs to the intestinal lumen in schistosomiasis.
The release of Schistosoma mansoni eggs to the intestinal lumen of Swiss Webster albino mice is dependent on the peri-ovular inflammatory cells, especially eosinophils. The cells corrode the epithelial basal membrane and provide an easily penetrated environment for the eggs, allowing them to be passively expelled by intestinal peristalsis.
D000818:Animals; D004804:Eosinophils / Q000502:physiology*; D005243:Feces / Q000469:parasitology*; D007422:Intestines / Q000648:ultrastructure*; D010063:Ovum / Q000648:ultrastructure*; D051381:Rats; D011919:Rats, Inbred Strains; D012550:Schistosoma mansoni / Q000502:physiology; D012555:Schistosomiasis mansoni / Q000469:parasitology*