Tocainide-associated neutropenia and lupus-like syndrome.
Neutropenia in association with a lupus-like illness that developed after the introduction of tocainide therapy is described. The mechanism of drug-associated neutropenia and the manifestations of drug-associated lupus are briefly discussed.
D000380:Agranulocytosis / Q000139:chemically induced*; D006801:Humans; D008012:Lidocaine / Q000009:adverse effects / Q000031:analogs & derivatives*; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000139:chemically induced*; D013577:Syndrome; D016677:Tocainide
D016677:Tocainide; D008012:Lidocaine