[Interaction of androgens and estrogens in the control of reproduction].
Castrated male quail were injected with the synthetic oestrogen, diethylstylbestrol (DES) or the synthetic androgen, methyltrienolone (R 1881) or both compounds simultaneously. Both R 1881 and DES activated male sexual behaviour, inhibited LH and FSH secretion and increased hypothalamic aromatase activity. Additive effects between R 1881 and DES were observed for the induction of brain aromatase and for the inhibition of FSH secretion. As a consequence, mechanisms mediated by androgen and estrogen receptors must be involved in the control of these reproductive characteristics.
D000728:Androgens / Q000494:pharmacology*; D000818:Animals; D001141:Aromatase / Q000378:metabolism; D003370:Coturnix; D004054:Diethylstilbestrol / Q000494:pharmacology; D004357:Drug Synergism; D004963:Estrenes / Q000494:pharmacology; D004967:Estrogens / Q000494:pharmacology*; D005640:Follicle Stimulating Hormone / Q000378:metabolism; D007034:Hypothalamus, Posterior / Q000201:enzymology; D007986:Luteinizing Hormone / Q000378:metabolism; D008297:Male; D015741:Metribolone; D011301:Preoptic Area / Q000201:enzymology; D012098:Reproduction; D012726:Sexual Behavior, Animal / Q000187:drug effects*
D000728:Androgens; D004963:Estrenes; D004967:Estrogens; D015741:Metribolone; D004054:Diethylstilbestrol; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D001141:Aromatase
Interactions des androgènes et des oestrogènes dans le contrôle de la reproduction.