Antimicrobial effects of some mono- and bishydrazones.
Antibacterial, antifungal and antiprotozoal effects of nine mono- and bishydrazones of glycolaldehyde, glyoxal, methoxyacetaldehyde and glutaraldehyde were studied using eight model organisms. It was found that bishydrazones are much more efficient antimicrobial agents than monohydrazones in the case of all model microorganisms.
D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001407:Bacillus / Q000187:drug effects; D001711:Biotransformation; D002176:Candida albicans / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D006835:Hydrazones / Q000378:metabolism / Q000494:pharmacology*; D008837:Micrococcus / Q000187:drug effects; D010659:Phenylhydrazines / Q000096:biosynthesis / Q000378:metabolism; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012441:Saccharomyces cerevisiae / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D014246:Trichomonas vaginalis / Q000187:drug effects
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D006835:Hydrazones; D010659:Phenylhydrazines