title: Cost savings and economic considerations using home intravenous antibiotic therapy for cystic fibrosis patients.
abstract: Our Cystic Fibrosis (CF) Center made an effort to utilize home intravenous antibiotic therapy (HIVAT) as an alternative to continued hospitalization during a 1-year study. After thorough individual clinical and financial evaluation, 27 of 41 CF patients admitted for treatment, including antibiotic therapy, were selected for HIVAT to complete a 14- to 21-day treatment course (mean 15.1 days). The 27 patients (6-28 years old, mean 16 years) incurred a total of $698,587 in hospital charges and physician fees during 96 admissions. The average charge for 974 inpatient days was $717/day ($7,280 per admission). After an average of 10.2 days of inpatient care, the 27 patients underwent 79 courses of HIVAT for an additional 8 days; 21 additional HIVAT courses in six of these patients were initiated on an outpatient basis between frequent readmissions. The 811 days of HIVAT resulted in $85,027 total charges by two home care companies. The charges per day of HIVAT by one company were almost twice that of the other. The average daily cost of HIVAT was $108/day. If the HIVAT patients had remained hospitalized to complete the course of intravenous antibiotic therapy, the projected inpatient costs would have been $589,271. Therefore, the 811 days of HIVAT over a 1-year period resulted in total estimated direct cost savings of $501,770. The average savings per course of HIVAT was $5,017, or $618/day.(ABSTRACT TRUNCATED AT 250 WORDS)
mesh_terms: D000293:Adolescent; D000328:Adult; D002442:Ceftazidime / Q000008:administration & dosage*; D002648:Child; D003362:Cost-Benefit Analysis; D003550:Cystic Fibrosis / Q000150:complications / Q000191:economics*; D006699:Home Care Services / Q000191:economics*; D006760:Hospitalization / Q000191:economics; D006801:Humans; D007262:Infusions, Intravenous; D010406:Penicillins / Q000008:administration & dosage*; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000191:economics* / Q000209:etiology; D013982:Ticarcillin / Q000008:administration & dosage*; D014031:Tobramycin / Q000008:administration & dosage*
chemical_list: D010406:Penicillins; D002442:Ceftazidime; D013982:Ticarcillin; D014031:Tobramycin