Monkey pulp reactions to cavities treated with Gluma Dentin Bond and restored with a microfilled composite.
Deep buccal cavities were cut in 72 incisors and canines in six young monkeys. The cavities were restored as follows: Group One: acid etching of the enamel followed by an intermediate layer of unfilled resin and a light-cured microfilled composite. Group Two: acid etching of the enamel followed by treatment of the dentin with Gluma Cleanser and Gluma Bond. The cavities were restored as in Group One. Group Three: same procedure as in Group Two except for application of a calcium hydroxide cement on the pulpal wall prior to acid etching. Pulp reactions, presence and location of bacteria were studied after 8 and 90 days. A significant association between presence of bacteria and moderate to severe inflammatory reactions were observed. Bacteria were only found in a very few cavities pretreated with Gluma Dentin Bond. In general, slight inflammatory changes prevailed in Groups Two and Three. When the pulpal wall was extremely thin a toxic effect of Gluma Dentin Bond was observed.
D000269:Adhesives / Q000494:pharmacology; D000447:Aldehydes / Q000494:pharmacology*; D000818:Animals; D002522:Chlorocebus aethiops; D003188:Composite Resins / Q000009:adverse effects / Q000494:pharmacology*; D003737:Dental Cavity Preparation; D003782:Dental Pulp / Q000187:drug effects* / Q000473:pathology; D003793:Dental Restoration, Permanent; D003804:Dentin / Q000473:pathology; D005976:Glutaral / Q000009:adverse effects / Q000494:pharmacology*; D011109:Polymethacrylic Acids / Q000009:adverse effects / Q000494:pharmacology*; D011671:Pulpitis / Q000139:chemically induced / Q000473:pathology; D013997:Time Factors
D000269:Adhesives; D000447:Aldehydes; D003188:Composite Resins; D011109:Polymethacrylic Acids; C044372:Gluma; D005976:Glutaral