title: [Post-antibiotic effect of ciprofloxacin alone and in combination on Streptococcus faecalis].
abstract: Post-antibiotic effect (PAE) of ciprofloxacin has been studied on 2 strains of S. faecalis in the logarithmic phase after 2 exposure times and at concentrations ranging 0.5-10 times the MIC. At the end of the exposure period the antimicrobial is removed by dilution. Similar PAE is observed for ciprofloxacin and ofloxacin, higher than for pefloxacin. Ciprofloxacin-fosfomycin or ciprofloxacin-vancomycin combinations are indifferent or even antagonistic (vancomycin) in regards to PAE. Ciprofloxacin-penicillin or ciprofloxacin-netilmicin are weakly synergistic.
mesh_terms: D002939:Ciprofloxacin / Q000494:pharmacology*; D004357:Drug Synergism; D013293:Enterococcus faecalis / Q000187:drug effects*; D005578:Fosfomycin / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009428:Netilmicin / Q000494:pharmacology; D009643:Norfloxacin / Q000031:analogs & derivatives / Q000494:pharmacology; D015242:Ofloxacin; D010078:Oxazines / Q000494:pharmacology; D015366:Pefloxacin; D014640:Vancomycin / Q000494:pharmacology
chemical_list: D010078:Oxazines; D015366:Pefloxacin; D005578:Fosfomycin; D009428:Netilmicin; D002939:Ciprofloxacin; D014640:Vancomycin; D015242:Ofloxacin; D009643:Norfloxacin
vernacular_title: Effet post-antibiotique de la ciprofloxacine seule et en association sur Streptococcus faecalis.