Preparation and characterization of N epsilon-(2,3-dihydroxypropyl)-L-lysine and its phenylthiohydantoin derivative.
Convenient methods for preparative synthesis of N epsilon-(2,3-dihydroxypropyl)-L-lysine and its phenylthiohydantoin derivative are described. The former compound was characterized by elemental analysis, melting point, and ion-exchange chromatography and the latter by elemental analysis, melting point, UV-spectrum, HPLC and thin-layer chromatography. This study was performed for investigations of lysine residues in proteins.
D000596:Amino Acids / Q000032:analysis; D002851:Chromatography, High Pressure Liquid; D002852:Chromatography, Ion Exchange; D002855:Chromatography, Thin Layer; D008239:Lysine / Q000031:analogs & derivatives* / Q000032:analysis* / Q000138:chemical synthesis; D010669:Phenylthiohydantoin; D013056:Spectrophotometry, Ultraviolet
D000596:Amino Acids; D010669:Phenylthiohydantoin; C055073:N(6)-(2,3-dihydroxypropyl)lysine; D008239:Lysine