title: Brief information on an early phase-II study with deprenyl in demented patients.
abstract: Eleven elderly female patients (73-88 yrs) suffering from senile dementia of Alzheimer type (7 cases) and from multi-infarct dementia (4 cases) were treated with (-) deprenyl (Jumex) for 3 and 6 months respectively. Improvement was most frequent in SDAT patients and most pronounced as regards self-care, short-term memory, mental alertness and uncooperativeness.
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000188:drug therapy*; D003704:Dementia / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D010627:Phenethylamines / Q000627:therapeutic use*; D012642:Selegiline / Q000627:therapeutic use*
chemical_list: D010627:Phenethylamines; D012642:Selegiline