Peliosis hepatis, nodular regenerative hyperplasia of the liver, and light-chain deposition in a patient with Waldenström's macroglobulinemia.
We report the case of a female patient suffering from Waldenström's macroglobulinemia with three different liver lesions: peliosis hepatis, nodular regenerative hyperplasia, and light-chain deposits within the sinusoidal walls. We hypothesize that both peliosis hepatis and nodular regenerative hyperplasia might be the consequence of a disordered intrahepatic circulation determined by light-chain deposits infiltrating the sinusoidal walls.
D001706:Biopsy; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007147:Immunoglobulin Light Chains / Q000032:analysis; D008099:Liver / Q000473:pathology*; D008107:Liver Diseases / Q000209:etiology*; D008854:Microscopy, Electron; D008875:Middle Aged; D010382:Peliosis Hepatis / Q000209:etiology* / Q000473:pathology; D008258:Waldenstrom Macroglobulinemia / Q000150:complications* / Q000473:pathology
D007147:Immunoglobulin Light Chains