The Clatterbridge high-energy neutron therapy facility: specification and performance.
A new high-energy neutron therapy facility has been installed at the Douglas Cyclotron Centre, Clatterbridge Hospital, Merseyside, in order to extend the clinical trials of fast neutrons initiated by the Medical Research Council. The neutron beam is produced by bombarding a beryllium target with 62 MeV protons. The target is isocentrically mounted with the potential for 360 degrees rotation and has a fully variable collimator. This gives a range of rectilinear field sizes from 5 cm x 5 cm to 30 cm x 30 cm. Basic neutron beam data including output, field flatness, penumbra and depth-dose data have been measured. For a 10 cm x 10 cm field, the 50% depth dose occurs at 16.2 cm in water and the output is 1.63 cGy microA-1 min-1 at the depth of dose maximum. The effectiveness of the target shielding and the neutron-induced radioactivity in the treatment head have also been measured. It is concluded that the equipment meets both the design specifications and also fully satisfies criticisms of earlier neutron therapy equipment. A full radiation survey of the centre was also carried out and it was found that radiation levels are low and present no significant hazard to staff.
D002138:Calibration; D004867:Equipment Design; D005214:Fast Neutrons / Q000627:therapeutic use*; D006801:Humans; D009502:Neutrons / Q000627:therapeutic use*; D011829:Radiation Dosage; D011834:Radiation Monitoring / Q000379:methods; D011835:Radiation Protection / Q000379:methods; D011882:Radiotherapy, High-Energy / Q000295:instrumentation / Q000379:methods*