A Creutzfeldt-Jakob like syndrome due to lithium toxicity.
Two patients with lithium toxicity presented with a neurological syndrome suggesting a diagnosis of Creutzfeldt-Jakob disease. In both cases, the initial EEG was consistent with this diagnosis. Neither patient had permanent neurological sequelae and the EEG returned to normal. A careful drug history should be taken in any patient who presents with a rapidly progressive dementia even when the EEG supports a diagnosis of Creutzfeldt-Jakob disease.
D000368:Aged; D001714:Bipolar Disorder / Q000188:drug therapy*; D007562:Creutzfeldt-Jakob Syndrome / Q000139:chemically induced*; D004569:Electroencephalography; D005071:Evoked Potentials / Q000187:drug effects; D005260:Female; D006801:Humans; D008094:Lithium / Q000009:adverse effects* / Q000627:therapeutic use; D016651:Lithium Carbonate; D019966:Substance-Related Disorders / Q000209:etiology*
D016651:Lithium Carbonate; D008094:Lithium