title: In vitro activity of ciprofloxacin and ofloxacin against the Mycobacterium avium-intracellulare complex.
abstract: The in vitro activity of ciprofloxacin and ofloxacin against strains of Mycobacterium avium-intracellulare complex were studied by the standard 1% proportion method. Thirty-eight of 100 strains (30%) were inhibited by ciprofloxacin at 2 micrograms/ml and 11 of 30 strains (37%) were inhibited by ofloxacin at 8 microm/ml. Patients having these more susceptible isolates may potentially benefit from therapy with these agents [corrected].
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002939:Ciprofloxacin / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D009162:Mycobacterium avium / Q000187:drug effects*; D009163:Mycobacterium bovis / Q000187:drug effects; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D015242:Ofloxacin; D010078:Oxazines / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D010078:Oxazines; D002939:Ciprofloxacin; D015242:Ofloxacin