Computer-automated prediction of the mutagenicity of benzidine, 4,4"-diaminoterphenyl, 4-dimethylaminoazobenzene and 4-cyanodimethylaniline: comparison with the results of the Second UKEMS Collaborative Study.
There was agreement between the experimental results, obtained in the course of the Second UKEMS Collaborative Study, for the mutagenicity in Salmonella typhimurium of benzidine, 4,4"-diaminoterphenyl, 4-dimethylaminoazobenzene and 4-cyanodimethylaniline and the mutagenicity predicted by CASE (Computer Automated Structure Evaluation), a recently developed artificial intelligence system.
D000814:Aniline Compounds / Q000009:adverse effects*; D001560:Benzidines / Q000009:adverse effects*; D012984:Software; D013730:Terphenyl Compounds / Q000009:adverse effects*; D004124:p-Dimethylaminoazobenzene / Q000009:adverse effects*
D000814:Aniline Compounds; D001560:Benzidines; D013730:Terphenyl Compounds; C029876:benzidine; C045996:4,4''-diaminoterphenyl; C042318:4-cyano-N,N-dimethylaniline; D004124:p-Dimethylaminoazobenzene