title: Formation of some extracellular enzymes during the exponential growth of Bacillus subtilis.
abstract: The formation of the exoenzymes, neutral and alkaline proteinase as well as alpha-amylase of Bacillus subtilis, is characterized by the same time course. The exoenzyme formation starts in the exponential phase of growth by an excess of C and N sources. We assume that carbon metabolism of pyruvate is responsible for the exoenzyme formation during this growth phase. The proteinase formation at the transient and/or stationary phase of growth is related to amino acid limitation.
mesh_terms: D000409:Alanine / Q000378:metabolism; D001412:Bacillus subtilis / Q000201:enzymology / Q000254:growth & development* / Q000378:metabolism; D010450:Endopeptidases / Q000096:biosynthesis; D005110:Extracellular Space / Q000201:enzymology* / Q000382:microbiology; D007700:Kinetics; D008666:Metalloendopeptidases / Q000096:biosynthesis; D011773:Pyruvates / Q000378:metabolism; D019289:Pyruvic Acid; D012697:Serine Endopeptidases; D000516:alpha-Amylases / Q000096:biosynthesis
chemical_list: D011773:Pyruvates; D019289:Pyruvic Acid; D000516:alpha-Amylases; D010450:Endopeptidases; D012697:Serine Endopeptidases; C032923:microbial serine proteinases; D008666:Metalloendopeptidases; C052706:neutral proteinase, cervical; D000409:Alanine