[Molecular genetic study of the cut locus of Drosophila melanogaster. V. The suffix sequence found in the locus is involved in the 3'-end maturation of different Drosophila mRNAs].
The nucleotide sequences of 8 genomic and 2 mRNA copies of the suffix were studied. It was found that this short repeat (265 bp) forms the last exon (73 bp) in different developmentally regulated Drosophila genes. The functioning genes contain short insertions carrying polyadenylation signals and polyadenylation sites at the same position of the suffix. It was shown that the suffix sequence is directly involved in the formation of the last splicing site and 3'-end maturation of mRNA.
D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular / Q000379:methods; D004247:DNA / Q000235:genetics; D004331:Drosophila melanogaster; D005091:Exons; D005796:Genes; D008969:Molecular Sequence Data; D012326:RNA Splicing; D012333:RNA, Messenger / Q000235:genetics*; D012091:Repetitive Sequences, Nucleic Acid; D014158:Transcription, Genetic
D012333:RNA, Messenger; D004247:DNA
Molekuliarno-geneticheskoe izuchenie lokusa cut Drosophila melanogaster. Soobshchenie V. Suffiks-posledovatel'nost', obnaruzhennaia v lokuse, vovlechena v 3'-kontsevoe sozrevanie raznykh mRNK drozofily.