title: Acute lymphoblastic leukemia in childhood.
abstract: This article reviews the current biologic understanding of acute lymphoblastic leukemia and describes current approaches to treatment. It discusses the areas likely to be the focus of future research for this disease, including therapy for high-risk patients, understanding the reasons for treatment failure, and identification of new antileukemic agents.
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D003131:Combined Modality Therapy; D006801:Humans; D007945:Leukemia, Lymphoid / Q000145:classification / Q000628:therapy; D008577:Meningeal Neoplasms / Q000517:prevention & control; D011882:Radiotherapy, High-Energy