Increased MR signal intensity secondary to chronic cervical cord compression.
Magnetic resonance images of 128 patients with compressive lesions of the cervical spinal canal were reviewed to determine whether a high signal intensity lesion within the spinal cord was present on T2 and proton density weighted spin echo images. Such high signal intensity was observed in 24 cases or 18.8%. The incidence was higher in herniated disk (32.4%), atlanto-axial dislocation (28.6%), and ossification of the posterior longitudinal ligament (22.7%), whereas the abnormality was found sporadically in cervical spondylosis and vertebral body tumors. The high intensity lesion on T2 weighted images was generally observed in patients with constriction or narrowing of the spinal cord. The lesion was not demonstrated on T1 weighted spin echo images. Spinal cord constriction or localized narrowing seemed to be the most important predisposing factor in producing such a high signal intensity. The pathophysiologic basis of such an abnormality was presumed to be myelomalacia or cord gliosis secondary to a long-standing compressive effect of the spinal cord.
D001268:Atlanto-Axial Joint / Q000293:injuries; D002574:Cervical Vertebrae / Q000473:pathology; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000473:pathology; D004204:Joint Dislocations / Q000473:pathology; D008022:Ligaments / Q000473:pathology; D008279:Magnetic Resonance Imaging; D009999:Ossification, Heterotopic / Q000473:pathology; D013116:Spinal Cord / Q000473:pathology; D013117:Spinal Cord Compression / Q000473:pathology*; D013128:Spinal Osteophytosis / Q000473:pathology