title: Impotence: treatment by autoinjection of vasoactive drugs.
abstract: One hundred and twenty five men with psychogenic or organic impotence used autoinjection of the penile corpora cavernosa with either papaverine or papaverine and phentolamine for a mean period of 10.5 months (range 1-24 months) to achieve penile erection for sexual intercourse. Prolonged (over four hours) painless erection resulted from 34 of the 3513 self administered injections. This seems to be a highly effective approach to treating impotence irrespective of the aetiology.
mesh_terms: D000328:Adult; D000368:Aged; D004338:Drug Combinations; D007172:Erectile Dysfunction / Q000188:drug therapy*; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D010208:Papaverine / Q000008:administration & dosage* / Q000627:therapeutic use; D010410:Penile Erection / Q000187:drug effects; D010646:Phentolamine / Q000008:administration & dosage* / Q000627:therapeutic use; D012646:Self Administration
chemical_list: D004338:Drug Combinations; D010208:Papaverine; D010646:Phentolamine