[Mechanoreceptor sensitivity of the frog lung to carbon dioxide].
To reveal CO2-sensitive receptors in the lungs of frogs, studies have been made of the pattern of afferent impulse activity in the pulmonary branch of the vagal nerve in lung preparations during their extension by gaseous mixtures containing 5-8% of CO2. No specific CO2-sensitive chemoreceptors were found. It was found that pulmonary mechanoreceptors exhibit sensitivity to elevated CO2 concentrations which significantly decrease impulse activity in slowly and rapidly adapting mechanoreceptors. It is concluded that the sensitivity of pulmonary mechanoreceptors to CO2 is formed in terrestrial vertebrates at early phylogenetic stages.
D000344:Afferent Pathways / Q000502:physiology; D000818:Animals; D002245:Carbon Dioxide / Q000494:pharmacology*; D002628:Chemoreceptor Cells / Q000187:drug effects; D066298:In Vitro Techniques; D008168:Lung / Q000187:drug effects* / Q000294:innervation; D008465:Mechanoreceptors / Q000187:drug effects*; D011896:Rana temporaria; D014630:Vagus Nerve / Q000502:physiology
D002245:Carbon Dioxide
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