Corpus callosotomy for epilepsy. I. Seizure effects.
Twenty-two patients were analyzed 2 or more years after corpus callosum section (9 partial, 13 total). Forty-one percent had class 1 outcome (elimination of secondarily generalized and complex partial seizures), 32% had class 2 outcome (elimination of secondarily generalized seizures), and 27% had class 3 outcome (no appreciable change). Total section was twice as effective in abolishing secondarily generalized seizures as was partial section (77% versus 35%). Statistically significant associations were seen between focal CT lesions and class 1 outcome, and between IQ less than 45 and class 2 or 3 outcome.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003337:Corpus Callosum / Q000601:surgery*; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D004827:Epilepsy / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D004833:Epilepsy, Temporal Lobe / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D014057:Tomography, X-Ray Computed