title: A speculative model for the Rh blood groups.
abstract: Two closely linked structural loci, D and 'CcEe', are proposed as the basis of the Rh blood groups. Mutation and unequal crossing-over between the two loci at meiosis are considered as possible explanations for some rare Rh complexes. The theory predicts that complexes arising from unequal crossing-over would be expected to have aberrant Rh polypeptides.
mesh_terms: D000483:Alleles; D000941:Antigens / Q000235:genetics; D003434:Crossing Over, Genetic; D005796:Genes; D006801:Humans; D008957:Models, Genetic; D012204:Rh-Hr Blood-Group System / Q000235:genetics*
chemical_list: D000941:Antigens; D012204:Rh-Hr Blood-Group System; C026410:Rho(D) antigen