Cross-linking of collagen by ascorbate-copper ion systems.
Cross-linking occurred rapidly in collagen when it was treated with ascorbate-copper ion systems. Sodium dodecyl sulfate-polyacrylamide gel electrophoretic patterns of CNBr peptides suggest that in some respects the modifications by the ascorbate-copper ion systems mimicked those that occurred in collagen with aging.
D000818:Animals; D001205:Ascorbic Acid; D003094:Collagen / Q000378:metabolism*; D003300:Copper; D003432:Cross-Linking Reagents; D007477:Ions; D010434:Pepsin A / Q000378:metabolism; D051381:Rats
D003432:Cross-Linking Reagents; D007477:Ions; D003300:Copper; D003094:Collagen; D010434:Pepsin A; D001205:Ascorbic Acid