[Effects of GRF 1-29 in normal and hypotrophic lambs].
Injections of hGRF rapidly stimulated GH secretion in lamb and this response was significantly higher in hypotrophic than in normal lambs. The treatment had an effect on body composition reducing the retention of lipids and the energy level and increasing calcium and phosphorus content. The results showed that GRF affected both metabolism and skeletal growth of ruminants, stimulating specially the production of Sm-C and proliferation of chondrocytes.
D000818:Animals; D000831:Animals, Newborn; D001823:Body Composition / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects*; D013006:Growth Hormone / Q000378:metabolism*; D013007:Growth Hormone-Releasing Hormone / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D012756:Sheep / Q000254:growth & development*
D013006:Growth Hormone; D013007:Growth Hormone-Releasing Hormone
Effects du GRF 1-29 chez l'agneau normal et hypotrophique.