The inhibitory action of quinacrine on endotoxin-induced tissue factor expression in cultured human endothelial cells is due to cell injury.
D000225:Adenine / Q000378:metabolism; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000378:metabolism; D001779:Blood Coagulation Factors / Q000037:antagonists & inhibitors / Q000378:metabolism*; D002478:Cells, Cultured; D004727:Endothelium / Q000187:drug effects* / Q000378:metabolism; D004731:Endotoxins / Q000494:pharmacology*; D011464:Epoprostenol / Q000378:metabolism; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D010741:Phospholipases A / Q000037:antagonists & inhibitors; D011796:Quinacrine / Q000494:pharmacology* / Q000633:toxicity; D011863:Radioimmunoassay; D013925:Thromboplastin; D014316:Tritium
D001095:Arachidonic Acids; D001779:Blood Coagulation Factors; D004731:Endotoxins; C053675:endothelial cell procoagulant activity; D014316:Tritium; D016718:Arachidonic Acid; D013925:Thromboplastin; D011464:Epoprostenol; D007770:L-Lactate Dehydrogenase; D010741:Phospholipases A; D011796:Quinacrine; D000225:Adenine