title: [Surveillance of Neisseria gonorrhoeae strains isolated in Toulouse. In vitro antibiotic sensitivity and plasmid content].
abstract: The minimal inhibitory concentration (MIC) of twelve antibiotics was determined by the method of dilution in agar for 50 non penicillinase-producing and 15 penicillinase-producing Neisseria gonorrhoeae (PPNG) strains. The commonly used antibiotics are active in vitro against all the strains. For the non PPNG stains, no difference was observed between the MICs with a previous investigation, in 1980. New quinolones are highly active against all the strains tested but two, with decreased sensitivity. Since 1980, 16 PPNG strains were isolated (2.2%) and analysed for plasmid content. Asian type plasmid (7.4 kb) was present in 9 strains and african type (5.3 kb) in 7 strains. The conjugative plasmid (39 kb) was present in 5 strains and the cryptic plasmid (4.4 kb) in all the strains.
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D005602:France; D006069:Gonorrhea / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D006801:Humans; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests; D009344:Neisseria gonorrhoeae / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics; D010405:Penicillinase / Q000096:biosynthesis; D011815:R Factors
chemical_list: D000900:Anti-Bacterial Agents; D010405:Penicillinase
vernacular_title: Surveillance des souches de Neisseria gonorrhoeae isolées à Toulouse. Sensibilité aux antibiotiques in vitro et contenus plasmidiques.