[Effect of oxygen inhalation on the respiration function during exercise under conditions of added resistance to respiration].
Experiments were performed to investigate the effect of added resistance to inspiratory, expiratory and inspiratory-expiratory respiration on lung ventilation and pACO2 during exercise when breathing air or oxygen. Increase of resistance to respiration, particularly inspiratory-expiratory; reduced the work-induced growth of ventilation which caused pACO2 to increase. Oxygen inhalation aggravated those shifts significantly. The adverse effect of hyperoxia on the respiration function when exercise was combined with added resistance to respiration seems to be associated with inhibition of the respiration center produced by the lack of hyperoxid stimulation.
D000328:Adult; D002245:Carbon Dioxide / Q000378:metabolism; D002319:Cardiovascular System / Q000187:drug effects; D006801:Humans; D008297:Male; D010100:Oxygen / Q000009:adverse effects / Q000494:pharmacology*; D010101:Oxygen Consumption; D005082:Physical Exertion; D012119:Respiration / Q000187:drug effects*; D012129:Respiratory Function Tests
D002245:Carbon Dioxide; D010100:Oxygen
Vliianie ingaliatsii kisloroda na funktsii respiratornoĭ sistemy pri myshechnoĭ nagruzke v usloviiakh dobavochnogo soprotivleniia dykhaniiu.