[Disordered learning and sleep structure in rats with a cobalt-induced epileptogenic focus in the sensorimotor cortex].
The influence of cobalt-induced epileptogenic foci in the somatosensory area of the cerebral cortex on sleep-wakefulness pattern has been studied in rats and the data obtained were compared with the learning ability of rats. It has been established that the formation of cobalt-induced epileptogenic foci may result in a decreased ability to learn that correlated with the selectivity of phasic components of the paradoxical sleep hippocampal theta-rhythm.
D000818:Animals; D002908:Chronic Disease; D003035:Cobalt / Q000633:toxicity*; D003214:Conditioning, Classical / Q000502:physiology; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000139:chemically induced / Q000150:complications* / Q000503:physiopathology; D006624:Hippocampus / Q000187:drug effects / Q000503:physiopathology; D007859:Learning Disabilities / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D008568:Memory / Q000502:physiology; D051381:Rats; D012890:Sleep / Q000502:physiology; D012893:Sleep Wake Disorders / Q000209:etiology* / Q000503:physiopathology; D013003:Somatosensory Cortex / Q000187:drug effects* / Q000503:physiopathology; D014851:Wakefulness / Q000502:physiology
D003035:Cobalt
Narushenie obucheniia i struktury sna u krys s épileptogennym kobal'tovym ochagom v sensomotornoĭ oblasti kory.