title: The influence of pyrithione on the growth of micro-organisms.
abstract: Pyrithione was active against a range of micro-organisms, the most resistant being Gram-negative bacteria. The growth curves for Klebsiella pneumoniae and Bacillus licheniformis showed a drug-dependent lag phase. Candida albicans grew with a drug-dependent growth rate. EDTA antagonized the effects of pyrithione.
mesh_terms: D001409:Bacillus cereus / Q000187:drug effects / Q000254:growth & development; D001412:Bacillus subtilis / Q000187:drug effects / Q000254:growth & development; D004492:Edetic Acid / Q000494:pharmacology; D005658:Fungi / Q000254:growth & development*; D006090:Gram-Negative Bacteria / Q000187:drug effects / Q000254:growth & development*; D006094:Gram-Positive Bacteria / Q000187:drug effects / Q000254:growth & development*; D007711:Klebsiella pneumoniae / Q000187:drug effects / Q000254:growth & development*; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000254:growth & development; D011725:Pyridines / Q000494:pharmacology*; D013871:Thiones
chemical_list: D011725:Pyridines; D013871:Thiones; C008704:pyrithione; D004492:Edetic Acid