Intraventricular hemorrhage in the newborn beagle puppy. A limited model of intraventricular hemorrhage in the premature infant.
The term beagle puppy has been used extensively as an experimental model of intraventricular hemorrhage (IVH) in the preterm infant. Fourteen variables were selected which were considered theoretically important to both the model and the preterm infant, and the data were subjected to discriminant analysis. Use of only three variables in combination correctly predicted whether an animal would sustain germinal matrix hemorrhage: baseline blood pressure, Pco2, and temperature. The model does not involve ischemia, which appears to be the sentinel but not singular insult in the IVH of preterm infants.
D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D001158:Arteries; D001794:Blood Pressure; D001831:Body Temperature; D002245:Carbon Dioxide / Q000097:blood; D002543:Cerebral Hemorrhage / Q000503:physiopathology / Q000517:prevention & control / Q000662:veterinary*; D002552:Cerebral Ventricles; D004195:Disease Models, Animal; D004283:Dog Diseases / Q000517:prevention & control*; D004285:Dogs; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D010313:Partial Pressure
D002245:Carbon Dioxide