title: Occurrence of alkali-labile sites in pulse labelled DNA of Escherichia coli after the action of DNA-damaging chemicals.
abstract: UV irradiated E. coli cells contain alkali labile sites in their DNA daughter chains. It is shown here that the occurrence of alkali labile sites in the newly synthesized DNA is a more common phenomenon. It occurred after treatment with two different DNA damaging chemicals, but not after treatment with nalidixic acid.
mesh_terms: D004249:DNA Damage; D004269:DNA, Bacterial / Q000096:biosynthesis / Q000187:drug effects*; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics* / Q000528:radiation effects; D008770:Methylnitrosourea / Q000494:pharmacology*; D016685:Mitomycin; D008937:Mitomycins / Q000494:pharmacology*; D009268:Nalidixic Acid / Q000494:pharmacology*
chemical_list: D004269:DNA, Bacterial; D008937:Mitomycins; D009268:Nalidixic Acid; D016685:Mitomycin; D008770:Methylnitrosourea