Increased frequency of Rh(E) in acute appendicitis.
In 64 children with histopathologically confirmed acute appendicitis, the Rh(E) antigen was found to be more frequent than in corresponding, ethnically and geographically matched controls. The Rh phenotype responsible for the increase of E appeared to be CcD-Ee. The difference was highly significant and supported the hypothesis of a polygenic predisposition to acute appendicitis.
D000208:Acute Disease; D000483:Alleles; D001064:Appendicitis / Q000235:genetics*; D005787:Gene Frequency; D006801:Humans; D010641:Phenotype; D012204:Rh-Hr Blood-Group System / Q000235:genetics*
D012204:Rh-Hr Blood-Group System