[Effects of GRF 1-44 on the eating behavior of sheep as a function of the type of feed (hay vs concentrate) and/or the effect of blood insulin].
While intracerebroventricular (ICV) or intravenous (IV) administration of GRF1-44 enhanced te daily food intake in hay-fed ewes, only the first hour of intake was enhanced in concentrate-fed ewes given centrally administered GRF. Previous insulin administration (ICV or IV) suppressed the orexigenic effects of GRF in hay-fed ewes, suggesting that insulin response to a concentrate meal might result in the early blockade of the orexigenic effects of GRF.
D000821:Animal Feed; D000818:Animals; D005247:Feeding Behavior / Q000187:drug effects*; D013007:Growth Hormone-Releasing Hormone / Q000008:administration & dosage / Q000494:pharmacology*; D007275:Injections, Intravenous; D007276:Injections, Intraventricular; D007328:Insulin / Q000008:administration & dosage / Q000494:pharmacology*; D010446:Peptide Fragments / Q000008:administration & dosage / Q000494:pharmacology*; D012756:Sheep
D007328:Insulin; D010446:Peptide Fragments; D013007:Growth Hormone-Releasing Hormone
Effets du GRF1-44 sur le comportement alimentaire du mouton en fonction de la nature du régime alimentaire (foin vs concentré) et/ou de l'insulinémie.