Apoprotein AII in acute pancreatitis: intriguing improvement in the prediction of fatal outcome.
In spite of significant advances in the past decade, assessing of severe prognosis in acute pancreatitis remains an improvable problem. Actually the standardized means are clinical, multiple laboratory and peritoneal lavage. In a series of 20 subsequent cases of acute pancreatitis with a lethality of 30%, apolipoprotein AII has proven to be a predictor of fatal outcome with a sensitivity in the range of all other methods together. Competitive replacement of Apo AII by serum amyloid like substance A as an indicator for the amount of necrosis would explain this relation. Whether this suggestion can be confirmed by ongoing work or not, apolipoprotein AII merits attention in this context.
D000208:Acute Disease; D000328:Adult; D016633:Apolipoprotein A-II; D001054:Apolipoproteins A / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000097:blood* / Q000401:mortality; D011379:Prognosis
D016633:Apolipoprotein A-II; D001054:Apolipoproteins A