Adenosine induced delay of expression of AIDS virus, HIV, in H9T cells.
Adenosine reduced the expression of CD4 antigen both in HIV infected and uninfected H9 T cells. The continuous presence of adenosine (1 mumol/ml) resulted in a remarkable delay of HIV expression in the infected cells. A relationship is suggested in the effects of HIV and adenosine on the human T cells.
D000241:Adenosine / Q000494:pharmacology*; D000954:Antigens, Surface / Q000276:immunology; D000956:Antigens, Viral / Q000276:immunology; D002460:Cell Line; D006678:HIV / Q000276:immunology* / Q000472:pathogenicity; D006801:Humans; D011948:Receptors, Antigen, T-Cell / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology / Q000382:microbiology*
D000954:Antigens, Surface; D000956:Antigens, Viral; D011948:Receptors, Antigen, T-Cell; D000241:Adenosine