title: [A new method of determining the virulence of nontubercular mycobacteria and weakly virulent Mycobacterium tuberculosis].
abstract: A new method for enhancing the sensitivity of white mice to infection with faintly virulent mycobacteria is proposed. The method consists in the sensitization of animals with pertussis monovaccine introduced in a single-intraperitoneal injection 7 days before the infection of animals with the culture under study. The method permitted the detection of residual virulence in all opportunistic mycobacteria under study.
mesh_terms: D000818:Animals; D001431:Bacteriological Techniques; D006854:Hydrocortisone / Q000494:pharmacology; D007113:Immunity, Innate / Q000187:drug effects; D007114:Immunization; D051379:Mice; D009161:Mycobacterium / Q000472:pathogenicity*; D009162:Mycobacterium avium / Q000472:pathogenicity*; D009168:Mycobacterium phlei / Q000472:pathogenicity*; D009169:Mycobacterium tuberculosis / Q000472:pathogenicity*; D009170:Nontuberculous Mycobacteria / Q000472:pathogenicity*; D010567:Pertussis Vaccine / Q000276:immunology; D014774:Virulence
chemical_list: D010567:Pertussis Vaccine; D006854:Hydrocortisone
vernacular_title: Novyĭ metod opredeleniia virulentnosti netuberkuleznykh i slabovirulentnykh tuberkuleznykh mikobakteriĭ.