title: [Home treatment in hemophilia].
abstract: 88 patients with severe haemophilia (66 with haemophilia A without inhibitor, 12 with haemophilia A and inhibitor, 10 with haemophilia B) currently receive comprehensive care at the Vienna haemophilia centre. Data available at the centre and a questionnaire answered by the hemophiliacs were used in order to evaluate the current situation of home care. At present, 62 (70%) out of 88 patients receive home treatment (51 with haemophilia A without inhibitor, 5 patients with haemophilia A and inhibitor and 6 with haemophilia B). For treatment of joint and muscle bleeding mean dosages of 15.3 units/kg body weight of factor VIII concentrate, 17.0 units/kg of factor IX concentrate and 30 units/kg of FEIBA were administered by the hemophiliacs. Children and young patients required higher doses (30 and 17.4 units/kg F VIII, respectively). Two thirds of the bleeding episodes were successfully treated by a single infusion. No severe side effects were observed during home treatment. Home treatment has been widely accepted by the patients. It is regarded as a practical and safe therapy and has improved the life quality of haemophiliac patients.
mesh_terms: D000293:Adolescent; D000328:Adult; D001779:Blood Coagulation Factors / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D005169:Factor VIII / Q000008:administration & dosage*; D006395:Hemarthrosis / Q000628:therapy; D006467:Hemophilia A / Q000628:therapy*; D002836:Hemophilia B / Q000628:therapy*; D006470:Hemorrhage / Q000628:therapy; D006701:Home Nursing; D006801:Humans; D008875:Middle Aged; D009135:Muscular Diseases / Q000628:therapy
chemical_list: D001779:Blood Coagulation Factors; C025667:prothrombin complex concentrates; D005169:Factor VIII
vernacular_title: Die Heimtherapie der Hämophilie.