title: Angiosarcoma of the thyroid: a light, electron microscopic and histoimmunological study.
abstract: A histologic, histoimmunological, and ultrastructural study of a primary angiosarcoma of the thyroid gland is reported. The occurrence of neoplastic cells positive for Factor VIII-related antigen and Ulex Europaeus Agglutinin-I and the presence in their cytoplasms of Weibel-Palade bodies are consistent with this diagnosis. These findings further support the view that primary angiosarcoma of the thyroid is a distinct pathological entity and should no longer be interpreted as a variant of a poorly differentiated carcinoma.
mesh_terms: D000368:Aged; D000941:Antigens / Q000032:analysis; D005169:Factor VIII / Q000032:analysis / Q000276:immunology; D006394:Hemangiosarcoma / Q000032:analysis / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D037102:Lectins / Q000032:analysis; D008297:Male; D037121:Plant Lectins; D013964:Thyroid Neoplasms / Q000032:analysis / Q000473:pathology* / Q000648:ultrastructure; D014841:von Willebrand Factor
chemical_list: D000941:Antigens; D037102:Lectins; D037121:Plant Lectins; C036850:Ulex europaeus lectins; D014841:von Willebrand Factor; D005169:Factor VIII