Fibrosarcoma mimicking breast fibromatosis.
Fewer than 1% of malignant breast tumors are sarcomas. Lack of correlation between the biologic behavior and histopathologic appearance of these tumors has been reported. A well-differentiated fibrosarcoma could be mistaken for breast fibromatosis, which may be a familial trait and may occur in Gardner syndrome. Forty-three cases of mammary fibromatosis have been reported. Most authors are concerned with misdiagnosis of breast fibromatosis as a malignant lesion leading to unnecessary mastectomy. However, the result can be disastrous when a well-differentiated fibrosarcoma is diagnosed as fibromatosis and the patient develops lung metastases.
D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005350:Fibroma / Q000175:diagnosis*; D005354:Fibrosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary; D008875:Middle Aged