Lung mechanics and blood gases in pregnant guinea pigs.
Lung resistance and compliance were measured in early pregnant, late pregnant and non pregnant guinea pigs. Lung resistance was increased, lung compliance was decreased in pregnancy. A new finding was the increase of chest wall compliance in the course of pregnancy. In order to obtain a sufficient gas exchange during artificial ventilation, pregnant animals have to be ventilated with a higher frequency or a higher pressure than non pregnant controls.
D000403:Airway Resistance; D000818:Animals; D002245:Carbon Dioxide / Q000097:blood*; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D007231:Infant, Newborn; D008170:Lung Compliance; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000097:blood / Q000502:physiology*
D002245:Carbon Dioxide