title: Ontogeny of antibody response to Brucella abortus in turkeys.
abstract: No differences were detected between large White Nicholas and small White Hybrid turkeys in antibody (AB) titers in birds vaccinated with Brucella abortus. Maximal AB titers occurred by 6 weeks of age and remained high throughout life. B. abortus elicits an AB response when injected at day of hatch while bursectomy at day of hatch and 2 days of age significantly depressed this response. There was an apparent immunological maturation process occurring to B. abortus in the bursa of Fabricius which contained for approximately 6 weeks.
mesh_terms: D000367:Age Factors; D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis*; D000942:Antigens, Bacterial / Q000008:administration & dosage; D001428:Bacterial Vaccines / Q000008:administration & dosage; D002003:Brucella abortus / Q000276:immunology*; D002060:Bursa of Fabricius / Q000254:growth & development / Q000276:immunology; D005260:Female; D008297:Male; D013045:Species Specificity; D014422:Turkeys / Q000254:growth & development / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D001428:Bacterial Vaccines