Lupus anticoagulants in children.
Although a great deal of information is available in the literature on the frequency, clinical/laboratory findings and significance of lupus anticoagulants in adults, little is known about such acquired inhibitors in children. Clinical and laboratory findings are presented on seven non-hemophiliac children, four females and three males, ranging in ages from three to 14 years, who developed such inhibitors. In most, the inhibitor is a transient phenomena and is not associated with a bleeding or thrombotic diathesis.
D000293:Adolescent; D001323:Autoantibodies / Q000032:analysis; D001778:Blood Coagulation Disorders / Q000276:immunology*; D001779:Blood Coagulation Factors / Q000032:analysis / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D016682:Lupus Coagulation Inhibitor; D008180:Lupus Erythematosus, Systemic / Q000276:immunology; D008297:Male; D010314:Partial Thromboplastin Time; D011517:Prothrombin Time
D001323:Autoantibodies; D001779:Blood Coagulation Factors; D016682:Lupus Coagulation Inhibitor