title: Intercalary heterochromatin of Drosophila as a potential model for human fragile sites.
abstract: We summarize our proposal that "intercalary heterochromatin" of Drosophila is a useful model for human fragile sites. Comparison with Drosophila site 11A suggests that the normal allele of fragile site Xq27 is a meiotic pairing site.
mesh_terms: D000818:Animals; D043283:Chromosome Fragile Sites; D002873:Chromosome Fragility; D004331:Drosophila melanogaster / Q000235:genetics*; D005600:Fragile X Syndrome / Q000235:genetics; D006570:Heterochromatin / Q000648:ultrastructure*; D006801:Humans; D008957:Models, Genetic; D014960:X Chromosome
chemical_list: D006570:Heterochromatin