Sporadic dysplastic nevus syndrome in a tyrosinase-positive oculocutaneous albino.
A case of dysplastic nevus syndrome in a 41-year-old tyrosinase-positive oculocutaneous albino man is presented. Clinically the patient exhibited multiple amelanotic lesions; histologic examination provided the diagnosis of dysplastic nevus syndrome. Fontana-Masson silver staining revealed the presence of melanin in the nevus cells. Hair bulbs incubated in tyrosine buffer produced melanin. This is the second reported case of dysplastic nevus syndrome in an oculocutaneous albino and the first case of dysplastic nevus syndrome in a tyrosinase-positive albino of which we are aware.
D000328:Adult; D000417:Albinism / Q000150:complications* / Q000201:enzymology; D004156:Catechol Oxidase / Q000097:blood*; D004416:Dysplastic Nevus Syndrome / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D008543:Melanins / Q000032:analysis; D014442:Monophenol Monooxygenase / Q000097:blood*; D012867:Skin / Q000032:analysis
D008543:Melanins; D004156:Catechol Oxidase; D014442:Monophenol Monooxygenase