title: [Results of myomectomy in obstructive cardiomyopathy. Apropos of 28 cases].
abstract: Hypertrophic obstructive cardiomyopathy, the pathogenesis of which is controverted, exposes the patient to the risk of sudden death and often evolves towards heart failure. When medical treatment is inadequate, surgery may be considered. The authors report their experience of myectomy performed in 28 subjects with pure obstructive cardiomyopathy. Despite a medical treatment based, in most cases, on beta-blockers, all patients showed severe symptoms, with syncopes in 39 p. 100 of the cases, stage 2 or over angina (Canadian Cardiovascular Society grading) in 57 p. 100 of the cases, and stage 3 or over dyspnoea (New York Heart Association grading) in 61 p. 100 of the cases. The intraventricular pressure gradient, measured in 25 patients, was 81.7 +/- 44.9 mmHg. The operation always consisted of myectomy according to the Morrow procedure, i.e. double myotomy of the subaortic septum extended on a length of at least 4 cm, with excision of the muscle between the two incisions. In addition, mitral valve replacement was performed in 13 patients who had severe mitral regurgitation. Three patients (7 p. 100) died with low cardiac output in the peri-operative period; pre-operatively, these patients were in a particularly poor condition. One patient died suddenly during the 4th post-operative month. The annual mortality rate therefore was 2.3 p. 100, and the actuarial survival rate at 8 years was 89.3 p. 100.(ABSTRACT TRUNCATED AT 250 WORDS)
mesh_terms: D000328:Adult; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications / Q000601:surgery*; D003645:Death, Sudden / Q000209:etiology; D004452:Echocardiography; D005260:Female; D006350:Heart Valve Prosthesis; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery; D011183:Postoperative Complications; D011379:Prognosis
vernacular_title: Résultats de la myomectomie dans la cardiomyopathie obstructive. A propos de 28 cas.