Severe allergic contact dermatitis secondary to nitroglycerin in a transdermal therapeutic system.
We describe two cases with a rare adverse effect of severe allergic contact dermatitis secondary to usage of a disc containing nitroglycerin. The causal agent is most probably trinitroglycerin as was demonstrated by skin patch testing using the North American Contact Dermatitis Group Method.
D000208:Acute Disease; D000787:Angina Pectoris / Q000150:complications / Q000188:drug therapy; D003877:Dermatitis, Contact / Q000209:etiology* / Q000473:pathology; D004890:Erythema / Q000139:chemically induced / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000008:administration & dosage / Q000009:adverse effects*; D010328:Patch Tests; D013997:Time Factors
D005996:Nitroglycerin