[Insomnia following a lesion of the paramedial preoptic area is reversible by inactivation of the posterior hypothalamus in the cat].
The bilateral intratissular injection of muscimol, an agonist of gamma amino butyric acid (GABA), induced a transient hypersomnia (slow wave sleep and paradoxical sleep) in an insomniac cat whose paramedial preoptic area had been previously bilaterally destroyed.
D000818:Animals; D001833:Body Temperature Regulation; D002415:Cats; D006970:Disorders of Excessive Somnolence / Q000503:physiopathology; D005260:Female; D007031:Hypothalamus / Q000503:physiopathology*; D007034:Hypothalamus, Posterior / Q000503:physiopathology*; D008297:Male; D011301:Preoptic Area / Q000293:injuries / Q000503:physiopathology*; D012890:Sleep / Q000502:physiology; D007319:Sleep Initiation and Maintenance Disorders / Q000503:physiopathology*
L'insomnie consécutive à la lésion de la région préoptique paramédiane est réversible par inactivation de l'hypothalamus postérieur chez le chat.