title: Sjögren's syndrome, vasculitis, and cryoglobulinaemia associated with a monoclonal IgM (kappa) paraprotein with rheumatoid factor activity.
abstract: A patient is described with primary Sjögren's syndrome with an infrequently reported complication--vasculitis and cryoglobulinaemia due to a monoclonal IgM (kappa) paraprotein with rheumatoid factor activity. The clinical and theoretical implications are discussed.
mesh_terms: D000368:Aged; D003449:Cryoglobulinemia / Q000150:complications*; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology; D007145:Immunoglobulin kappa-Chains / Q000276:immunology; D010266:Paraproteins / Q000276:immunology; D012217:Rheumatoid Factor / Q000276:immunology; D012859:Sjogren's Syndrome / Q000150:complications*; D014657:Vasculitis / Q000150:complications*
chemical_list: D007075:Immunoglobulin M; D007145:Immunoglobulin kappa-Chains; D010266:Paraproteins; D012217:Rheumatoid Factor