Low-dose irradiation to head, neck, or chest during infancy as a possible cause of thyroid carcinoma in teen-agers: a matched case-control study.
A matched case-control study was performed to identify the etiologic factors for thyroid carcinoma in teen-agers. Twenty-seven cases and 69 controls were investigated to assess the significance of various maternal and subject factors. Irradiation during infancy was the only factor which showed a statistically significant association with the incidence of thyroid cancer in teen-agers (summary X2 = 8.040; d.f. = 1; P less than 0.005). The estimated dose ranged from 0.2 to 40 rads on the head, neck, or chest during infancy.
D005260:Female; D005500:Follow-Up Studies; D006257:Head; D006801:Humans; D007223:Infant; D008297:Male; D009333:Neck; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D011859:Radiography / Q000009:adverse effects*; D013902:Radiography, Thoracic / Q000009:adverse effects*; D013964:Thyroid Neoplasms / Q000209:etiology*