The serodiagnosis of tuberculosis: a comparison of an enzyme-linked immunosorbent assay and a solid-phase radioimmunoassay.
Antibodies to a cytosolic fraction of Mycobacterium tuberculosis in sera from 104 patients with pulmonary tuberculosis and 141 age-matched healthy control subjects were quantitated by solid-phase radioimmunoassay (SPRIA) and an enzyme-linked immunosorbent assay (ELISA) technique. The SPRIA gave a greater discrimination than ELISA: in the former test 92% of patients had antibody levels in excess of those occurring in 97% of controls, while the corresponding figure with the latter was only 73%.
D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007214:Indonesia; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000276:immunology*; D011237:Predictive Value of Tests; D011863:Radioimmunoassay; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis*
D000907:Antibodies, Bacterial