Cellobiose/mannitol sugar absorption test in patients with dermatitis herpetiformis: a preliminary report.
An abnormal cellobiose/mannitol ratio is present in new patients presenting with dermatitis herpetiformis and in patients who have never adhered to a strict gluten-free diet. In patients with dermatitis herpetiformis in remission on a strict gluten-free diet, small bowel absorption as measured by the cellobiose/mannitol ratio is normal. It is suggested that cellobiose/mannitol ratio absorption is a useful screening test for the intestinal abnormality associated with dermatitis herpetiformis and failure of the test to return to normal could suggest poor dietary compliance.
D000328:Adult; D000368:Aged; D001284:Atrophy / Q000209:etiology; D001706:Biopsy; D002475:Cellobiose / Q000493:pharmacokinetics*; D003874:Dermatitis Herpetiformis / Q000178:diet therapy / Q000378:metabolism*; D004187:Disaccharides / Q000493:pharmacokinetics*; D005260:Female; D006801:Humans; D007408:Intestinal Absorption; D007583:Jejunum / Q000473:pathology; D008297:Male; D008353:Mannitol / Q000493:pharmacokinetics*; D008875:Middle Aged
D004187:Disaccharides; D002475:Cellobiose; D008353:Mannitol