title: Alteration in thermal stability of collagen and collagen-chondroitin-6-sulphate complex induced by histamine.
abstract: The effect of histamine (Hi) on thermal stability of triple helical structure of collagen alone and collagen-chondroitin-6-sulphate complex was studied. Hi increased the thermal stability of collagen and the complex in acidic pH and decreased it in neutral pH.
mesh_terms: D000818:Animals; D002807:Chondroitin / Q000031:analogs & derivatives; D002809:Chondroitin Sulfates; D002942:Circular Dichroism; D003094:Collagen; D006632:Histamine; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D011487:Protein Conformation; D011489:Protein Denaturation
chemical_list: D006632:Histamine; D002807:Chondroitin; D002809:Chondroitin Sulfates; D003094:Collagen