Pyoderma pathophysiology and management.
Cutaneous infections with Staphylococcus aureus, Streptococcus pyogenes, and Pseudomonas aeruginosa are major complications of epidermolysis bullosa. Application of impermeable occlusive dressings over denuded skin colonized with these bacteria results in rapid multiplication and the hazard of severe pyoderma. Approaches to the prophylactic treatment of these infections during the long-term management of epidermolysis bullosa are considered.
D000279:Administration, Cutaneous; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004820:Epidermolysis Bullosa / Q000150:complications*; D005227:Fatty Acids / Q000627:therapeutic use; D006801:Humans; D016712:Mupirocin; D009779:Occlusive Dressings / Q000009:adverse effects; D011711:Pyoderma / Q000209:etiology* / Q000628:therapy; D013207:Staphylococcal Skin Infections / Q000188:drug therapy / Q000209:etiology; D013290:Streptococcal Infections / Q000188:drug therapy / Q000209:etiology; D013297:Streptococcus pyogenes
D000900:Anti-Bacterial Agents; D005227:Fatty Acids; D016712:Mupirocin