Neuron-specific enolase and malignant lymphomas (23 cases).
The immunoreactivity of polyclonal antiserum to neuron-specific enolase (NSE) has been investigated. Twenty-three cases of malignant lymphoma (ML) were studied and compared with previously published reports. In our study 11 out of 23 cases showed strong or weak NSE positivity; any type of ML could be positive or negative even among B or T cell ML. This study indicated that polyclonal NSE is not a specific marker; it might be an inconstant marker of ML with no apparent correlation between reactivity and morphology or phenotype.
D000911:Antibodies, Monoclonal / Q000032:analysis; D003429:Cross Reactions; D006801:Humans; D007150:Immunohistochemistry; D008223:Lymphoma / Q000145:classification / Q000201:enzymology*; D010751:Phosphopyruvate Hydratase / Q000378:metabolism*
D000911:Antibodies, Monoclonal; D010751:Phosphopyruvate Hydratase