Antibodies to porcine uteroferrin used in measurement of human tartrate-resistant acid phosphatase.
The immunological similarity between human tartrate-resistant acid phosphatase (EC 3.1.3.2) and porcine uteroferrin previously reported for the isoenzyme from spleens of patients with leukemic reticuloendotheliosis (Ketcham et al., J Biol Chem 1985;260:5768-76) has been confirmed for partly purified acid phosphatase found in the spleen of a patient with Gaucher's disease, and for the corresponding isoenzyme in other tissues and serum. Anti-uteroferrin antibodies raised in rabbits have been used to demonstrate the feasibility of their application in an immunoassay for tartrate-resistant acid phosphatase in serum.
D000135:Acid Phosphatase / Q000032:analysis* / Q000276:immunology; D000906:Antibodies; D003429:Cross Reactions; D006801:Humans; D005779:Immunodiffusion; D007527:Isoenzymes; D008667:Metalloproteins / Q000276:immunology*; D013154:Spleen / Q000201:enzymology; D000071681:Tartrate-Resistant Acid Phosphatase; D013644:Tartrates
D000906:Antibodies; D007527:Isoenzymes; D008667:Metalloproteins; D013644:Tartrates; D000135:Acid Phosphatase; D000071681:Tartrate-Resistant Acid Phosphatase; C029768:tartaric acid