A new synthesis of 2'-C-methylnucleosides starting from D-ribose.
A general method have been developed for the synthesis of 2'-C-methylnucleosides from 2,3-O-isopropylidene-2-hydroxymethyl-5-O-trityl-D-ribofuranose (2).
D008745:Methylation; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D009705:Nucleosides / Q000138:chemical synthesis*; D012266:Ribose; D013329:Structure-Activity Relationship
D009705:Nucleosides; D012266:Ribose