Nucleotide sequences of three tRNA(Ser) from Drosophila melanogaster reading the six serine codons.
The nucleotide sequences of three serine tRNAs from Drosophila melanogaster, together capable of decoding the six serine codons, were determined. tRNA(Ser)2b has the anticodon GCU, tRNA(Ser)4 has CGA and tRNA(Ser)7 has IGA. tRNA(Ser)2b differs from the last two by about 25%. However, tRNA(Ser)4 and tRNA(Ser)7 are 96% homologous, differing only at the first position of the anticodon and two other sites. This unusual sequence relationship suggests, together with similar pairs in the yeasts Schizosaccharomyces pombe and Saccharomyces cerevisiae, that eukaryotic tRNA(Ser)UCN may be undergoing concerted evolution.
D000818:Animals; D000926:Anticodon; D001483:Base Sequence; D005075:Biological Evolution; D003062:Codon; D004331:Drosophila melanogaster / Q000235:genetics*; D005796:Genes; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D012331:RNA, Fungal / Q000235:genetics; D012345:RNA, Transfer, Amino Acid-Specific / Q000235:genetics*; D012362:RNA, Transfer, Ser / Q000235:genetics*; D012441:Saccharomyces cerevisiae / Q000235:genetics; D012568:Schizosaccharomyces / Q000235:genetics; D012689:Sequence Homology, Nucleic Acid
D000926:Anticodon; D003062:Codon; D012331:RNA, Fungal; D012345:RNA, Transfer, Amino Acid-Specific; D012362:RNA, Transfer, Ser