Characterization of a broad-scope amino acid transport system in sand dollars.
Both echinoderm embryos and adults take up alpha-amino acids by an apparent broad-scope transport system. This transporter can be characterized as follows: alanine transport is not blocked by alpha-(methylamino)isobutyric acid. Leucine and other lipophilic neutral amino acids are preferentially transported. Transport is sodium dependent and blocked by 2-aminobicyclo-[2,2,1]heptane-2-carboxycylic acid. Lysine and aspartate transport is inhibited by lipophilic neutral amino acids. Taurine, a beta-neutral amino acid, is translocated via a second and independent carrier.
D000596:Amino Acids / Q000037:antagonists & inhibitors / Q000493:pharmacokinetics*; D000818:Animals; D001692:Biological Transport; D002352:Carrier Proteins / Q000378:metabolism; D008239:Lysine / Q000494:pharmacology; D011392:Proline / Q000494:pharmacology; D012617:Sea Urchins / Q000378:metabolism*
D000596:Amino Acids; D002352:Carrier Proteins; D011392:Proline; D008239:Lysine