Selenalysine utilization by CHO cells.
CHO cells allowed to grow in a medium containing selenalysine can utilize it for protein synthesis. Selenalysine is incorporated into cell proteins in substitution of lysine: a maximum of 5% of protein lysine can be substituted. Protein lysine substitution by selenalysine can be correlated to the reduced viability of cells grown in its presence.
D000818:Animals; D002460:Cell Line; D006224:Cricetinae; D003412:Cricetulus; D005260:Female; D007700:Kinetics; D008239:Lysine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D016566:Organoselenium Compounds; D010053:Ovary; D012643:Selenium / Q000378:metabolism*
D016566:Organoselenium Compounds; C011351:selenalysine; D012643:Selenium; D008239:Lysine