Is nodular regenerative hyperplasia of the liver associated with azathioprine therapy after renal transplantation?
A 33-year-old man presented with hepatosplenomegaly and ascites 26 months after receiving a successful renal transplant. Immunosuppression consisted of low-dose prednisolone and azathioprine. Biopsy showed characteristic features of nodular regenerative hyperplasia of liver (NRHL), a condition which may be related to azathioprine therapy but has rarely been reported in association with renal transplantation.
D000328:Adult; D001379:Azathioprine / Q000009:adverse effects*; D006801:Humans; D006965:Hyperplasia; D016030:Kidney Transplantation; D008099:Liver / Q000473:pathology*; D008297:Male; D011183:Postoperative Complications / Q000209:etiology*; D012038:Regeneration
D001379:Azathioprine