Activity of acid phosphatase in target binding cells expressing NK cytotoxic potential.
Activity of acid phosphatase was analysed in the NK-effectors from human blood forming conjugates with K 562 cells. Presence of activity of acid phosphatase was associated with the cytolytic potential of the NK-effectors. The non-lytic target-binders did not express activity of this enzyme. The results suggest that activity of acid phosphatase in the effector cells of NK reaction is important in the lethal hit stage.
D000135:Acid Phosphatase / Q000378:metabolism*; D002460:Cell Line; D003602:Cytotoxicity, Immunologic; D006801:Humans; D007694:Killer Cells, Natural / Q000201:enzymology* / Q000276:immunology; D012016:Reference Values
D000135:Acid Phosphatase