[Correction of alloxan diabetes in rats using xenotransplantation of passaged cultures of human embryonic pancreatic beta cells].
The authors present experimental data on the antidiabetic effect of passaged human embryonic pancreatic beta-cells in their xenotransplantation to rats with alloxan diabetes. Intra-abdominal xenotransplantation of such cultures results in a stable compensation of glycemia in rats with experimental diabetes. These data are important in terms of a possibility to use passaged human embryonic pancreatic beta-cells for transplantation to patients with diabetes mellitus.
D000818:Animals; D002478:Cells, Cultured; D003921:Diabetes Mellitus, Experimental / Q000628:therapy*; D006801:Humans; D007515:Islets of Langerhans / Q000196:embryology; D016381:Islets of Langerhans Transplantation; D008297:Male; D051381:Rats; D014183:Transplantation, Heterologous
Korrektsiia alloksanovogo diabeta u krys s pomoshch'iu ksenotransplantatsii passirovannykh kul'tur beta-kletok podzheludochnoĭ zhelezy ploda cheloveka.