Management of gonococcal ophthalmia neonatorum with single-dose kanamycin and ocular irrigation with saline.
Two hundred nineteen neonates with gonococcal ophthalmia neonatorum, including 40 infected with penicillinase-producing strains, were treated as outpatients with a single intramuscular injection of 100 mg of kanamycin and hourly ocular irrigation with saline. Neisseria gonorrhoeae was isolated from three (1.4%) of the 212 babies attending for follow-up, and post-gonococcal conjunctivitis developed in 22 (10.4%) of those who returned for follow-up.
D000553:Ambulatory Care; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D007231:Infant, Newborn; D007612:Kanamycin / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D009344:Neisseria gonorrhoeae / Q000302:isolation & purification; D009878:Ophthalmia Neonatorum / Q000188:drug therapy* / Q000382:microbiology; D012462:Saline Solution, Hypertonic / Q000008:administration & dosage*; D012965:Sodium Chloride / Q000008:administration & dosage*; D007507:Therapeutic Irrigation
D012462:Saline Solution, Hypertonic; D012965:Sodium Chloride; D007612:Kanamycin