title: Haemostasis during treatment with ciprofloxacin.
abstract: The effects of ciprofloxacin, a new quinolone derivative with high activity on gram-negative aerobic bacteria and gram-positive cocci, on haemostasis were investigated in 11 healthy volunteers. No influence on platelet function was detectable. In some cases a slight reduction in antithrombin III activity was observed at the end of the therapy. No other changes were evident in the plasma coagulation parameters.
mesh_terms: D000990:Antithrombin III / Q000187:drug effects; D001780:Blood Coagulation Tests; D002939:Ciprofloxacin / Q000008:administration & dosage / Q000494:pharmacology*; D005169:Factor VIII / Q000187:drug effects; D005260:Female; D006487:Hemostasis / Q000187:drug effects*; D006801:Humans; D008297:Male; D010979:Platelet Function Tests
chemical_list: D002939:Ciprofloxacin; D000990:Antithrombin III; D005169:Factor VIII