title: Management of intraocular pressure during cardiopulmonary bypass.
abstract: Intraocular pressure was measured in two groups of patients undergoing cardiopulmonary bypass surgery. A control group received mannitol at the start of bypass in accordance with standard practice; pressure was found to rise by 6.4 mmHg. In a second group of patients mannitol was administered 30 min prior to bypass; pressure elevation of 2.4 mmHg was found. These findings are discussed in relation to other clinical observations during bypass and to ocular morbidity complicating bypass surgery.
mesh_terms: D002315:Cardiopulmonary Bypass / Q000009:adverse effects*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D007431:Intraoperative Complications / Q000517:prevention & control*; D008353:Mannitol / Q000008:administration & dosage
chemical_list: D008353:Mannitol