title: Linkage analysis of neurofibromatosis.
abstract: Linkage analysis of neurofibromatosis was performed using genes on chromosomes 1, 8, 11, and 12. No linkage was found between NF and C-myc, AT 3, IGF-1, PTH, and gamma globin genes. Evidence for linkage was found between C-ets 1, on the long arm of chromosome 11 and NF in two families with a lod score of 1.88 at theta = 0. More families are being studied to confirm this linkage.
mesh_terms: D002880:Chromosomes, Human, Pair 11; D008040:Genetic Linkage; D006801:Humans; D009456:Neurofibromatosis 1 / Q000235:genetics*; D011519:Proto-Oncogenes