[Characteristics of viral infections in patients with chronic obstructive bronchitis].
Virological and immunological studies on 53 patients with chronic obstructive bronchitis at the clinical stage of fading exacerbation were conducted. A high percentage of active viral infection (43%), persistence of viruses (25%) and virus-specific components (ribonucleoprotein in influenza) in the cells of brush biopsy bronchial mucosa specimens was characteristic for these patients. The respiratory-syncytial virus was the most common persisting virus (11%). A high percentage of association (72%) of respiratory viruses (influenza, adenoviruses) and pneumonia Mycoplasma contributed to an increase in a period of an infective process. The utmost decrease in indices of cellular immunity (natural killer cell activity, T-cell and phagocytosis function) was detected in a group of patients with a prolonged (over 4 months) virus persistence.
D000258:Adenovirus Infections, Human / Q000175:diagnosis / Q000382:microbiology; D000260:Adenoviruses, Human / Q000276:immunology / Q000302:isolation & purification; D000328:Adult; D000368:Aged; D001991:Bronchitis / Q000175:diagnosis* / Q000382:microbiology; D002908:Chronic Disease; D006801:Humans; D007111:Immunity, Cellular; D009980:Influenza A virus / Q000276:immunology / Q000302:isolation & purification; D007251:Influenza, Human / Q000175:diagnosis / Q000382:microbiology; D008875:Middle Aged; D009177:Mycoplasma pneumoniae / Q000276:immunology / Q000302:isolation & purification; D011019:Pneumonia, Mycoplasma / Q000175:diagnosis / Q000382:microbiology; D012136:Respiratory Syncytial Viruses / Q000276:immunology / Q000302:isolation & purification; D010253:Respirovirus Infections / Q000175:diagnosis / Q000382:microbiology; D013601:T-Lymphocytes / Q000276:immunology; D014777:Virus Diseases / Q000175:diagnosis* / Q000382:microbiology
Osobennosti virusnoĭ infektsii u bol'nykh khronicheskim obstruktivnym bronkhitom.