title: Lung mechanics and blood gases in pregnant guinea pigs.
abstract: Lung resistance and compliance were measured in early pregnant, late pregnant and non pregnant guinea pigs. Lung resistance was increased, lung compliance was decreased in pregnancy. A new finding was the increase of chest wall compliance in the course of pregnancy. In order to obtain a sufficient gas exchange during artificial ventilation, pregnant animals have to be ventilated with a higher frequency or a higher pressure than non pregnant controls.
mesh_terms: D000403:Airway Resistance; D000818:Animals; D002245:Carbon Dioxide / Q000097:blood*; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D007231:Infant, Newborn; D008170:Lung Compliance; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000097:blood / Q000502:physiology*
chemical_list: D002245:Carbon Dioxide