title: [Treatment of acute inner ear diseases (sudden deafness and vestibular disorder) with meclofenoxate and acetylsalicylic acid].
abstract: Sixty patients suffering from an acute inner ear disease were treated by a combination of acetylsalicylic acid (Micristin), an inhibitor of platelet aggregation, and meclofenoxate (Cerutil), a nootropic drug. The success rate in 26 patients with acute isolated unilateral vestibular disorder was 73% (69% with complete recovery), and 83% (57% complete remission) in 34 patients with sudden deafness, with an average hearing improvement of 22.4 dB. The success rate of this therapy was similar to that achieved by the usual therapy or no treatment in subjects with sudden deafness and vestibular disorder which we reported in 1984.
mesh_terms: D000208:Acute Disease; D001241:Aspirin / Q000627:therapeutic use*; D006016:Glycolates / Q000627:therapeutic use*; D003639:Hearing Loss, Sudden / Q000188:drug therapy*; D006801:Humans; D007759:Labyrinth Diseases / Q000188:drug therapy*; D002504:Meclofenoxate / Q000627:therapeutic use*; D008875:Middle Aged
chemical_list: D006016:Glycolates; D002504:Meclofenoxate; D001241:Aspirin
vernacular_title: Zur Therapie akuter Innenohrerkrankungen (Hörsturz und Vestibularisausfall) mit Meklofenoxat und Azetylsalizylsäure.