Soluble IL-2 receptors in acute and subacute encephalitis.
Elevated levels of soluble interleukin-2 receptors were present in the serum from patients with acute primary and postinfectious encephalitis and subacute sclerosing panencephalitis. In addition, soluble interleukin-2 receptors were detected in the cerebrospinal fluid from patients with acute primary encephalitis. Their presence in the cerebrospinal fluid was not explained by damage to the blood-brain barrier and our data attest to their local origin. This suggests that it may be possible in certain neurological diseases to detect cerebral T-lymphocyte activation through a specific marker in the cerebrospinal fluid.
D000328:Adult; D002675:Child, Preschool; D004660:Encephalitis / Q000097:blood* / Q000134:cerebrospinal fluid; D006801:Humans; D007223:Infant; D008875:Middle Aged; D011971:Receptors, Immunologic / Q000097:blood* / Q000134:cerebrospinal fluid; D015375:Receptors, Interleukin-2; D013344:Subacute Sclerosing Panencephalitis / Q000097:blood* / Q000134:cerebrospinal fluid
D011971:Receptors, Immunologic; D015375:Receptors, Interleukin-2