The latex condom, an efficient barrier against sexual transmission of AIDS-related viruses.
Using a mechanical model, we studied human immunodeficiency virus (HIV) leakage through six different trademark condoms. The presence of the recovered virus was determined after passage to MT-2 cells and to cultured mitogen-stimulated normal human peripheral blood mononuclear cells (PMC). Only the natural membrane condom showed virus leakage after inside pressure. In addition, the kinetics of virus inactivation at 37 degrees C were followed inside and outside the condom. The virus was partially inactivated after 10 min at 37 degrees C inside the condom, but the degree of inactivation seemed higher in some of the trademark condoms.
D000163:Acquired Immunodeficiency Syndrome / Q000517:prevention & control*; D003275:Contraceptive Devices, Male; D006678:HIV; D006801:Humans; D007840:Latex
D007840:Latex