[Absence of paradoxical sleep rebound in hypophysectomized rats pretreated at birth with sodium glutamate].
Control untreated female rats and rats pretreated at birth with ten injections of monosodium glutamate (MSG; 4 mg/g b.w.) were hypophysectomized (Hypox) at 45-60 days of age and their sleep-waking cycle continuously registered. After 24 hrs. of PS deprivation, there was an immediate increase of PS (rebound) in the control Hypox and MSG rats while there was no increase in Hypox-MSG rats. Factors from arcuate nucleus and/or from the hypophysis are probably involved in the mechanisms of PS rebound.
D000818:Animals; D000831:Animals, Newborn; D001921:Brain / Q000187:drug effects / Q000502:physiology; D005971:Glutamates / Q000494:pharmacology*; D007016:Hypophysectomy; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values; D012895:Sleep, REM / Q000187:drug effects / Q000502:physiology*; D012970:Sodium Glutamate / Q000494:pharmacology*; D014851:Wakefulness / Q000187:drug effects / Q000502:physiology
D005971:Glutamates; D012970:Sodium Glutamate
Absence de rebond de sommeil paradoxal chez des rats hypophysectomisés et prétraités à la naissance par le glutamate de sodium.