Absence attacks precipitated by long-lasting subclinical temporal discharges.
The subject of this single-case report is a girl whose absence seizures and the corresponding 3 Hz generalized, symmetrical spike-wave pattern were preceded by continuous, long-lasting left temporal subclinical epileptic discharges probably associated with an atrophic lesion in the hemisphere. The authors' meaning is that like in experimental human conditions (stereo-EEG studies), epileptic neuronal malfunctioning of a localized nature is also able to precipitate true absence attacks. This idea is supported by electroencephalographic and pharmacological arguments.
D000927:Anticonvulsants / Q000627:therapeutic use; D002648:Child; D004569:Electroencephalography; D004832:Epilepsy, Absence / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D006801:Humans; D013702:Temporal Lobe / Q000503:physiopathology*; D014635:Valproic Acid / Q000627:therapeutic use
D000927:Anticonvulsants; D014635:Valproic Acid