A simplified method for monitoring blood concentration of cyclosporin by a finger-stab technique.
We have developed a simple method of sample collection which allows the measurement of cyclosporin (CsA) to be made from blood obtained from a finger stab and collected onto filter paper. CsA concentrations estimated from blood spots and venous samples obtained at the same time showed good correlation. This method has various practical applications: peak and trough blood CsA concentrations (as well as profiles) may be routinely measured from samples collected by patients at home; it may be of particular value in children and other patients with poor venous access.
D003524:Cyclosporins / Q000097:blood*; D006801:Humans
D003524:Cyclosporins