title: [Plasticity and its physiological markers in the microsystem of cortical neurons during repeated local stimulation].
abstract: Separate neuronal microsystems in the sensomotor cerebral cortex are able to exhibit the functional plasticity under conditions of repeated action of acetylcholine applied microiontophoretically. The characteristic properties of dynamics in activity of single cortex neurones are determined mainly by the initial reactivity to transmitter and by the state of nervous cells of the surrounding microsystem. The composition and succession of response components as well the duration of excitatory stage of reaction to acetylcholine serve as physiological markers of plastic properties of neurones in cortical microsystem.
mesh_terms: D000109:Acetylcholine / Q000008:administration & dosage; D000818:Animals; D002540:Cerebral Cortex / Q000187:drug effects / Q000502:physiology*; D004533:Egtazic Acid / Q000008:administration & dosage; D005071:Evoked Potentials / Q000187:drug effects; D005260:Female; D006185:Habituation, Psychophysiologic / Q000187:drug effects / Q000502:physiology; D007478:Iontophoresis / Q000379:methods; D008839:Microelectrodes; D009473:Neuronal Plasticity / Q000187:drug effects; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D013268:Stimulation, Chemical; D013569:Synapses / Q000187:drug effects / Q000502:physiology
chemical_list: D004533:Egtazic Acid; D000109:Acetylcholine
vernacular_title: Plastichnost' i ee fiziologicheskie markery v mikrosisteme korkovykh neĭronov pri mnogokratnoĭ lokal'noĭ stimuliatsii.