[A case of colorectal cancer showing complete response to UFT].
A 33-year-old male patient underwent a low anterior resection for sigmoid colon cancer. Bloody stool developed about one month after discharge and a small, circumscribed, ulcerated adenocarcinoma was found about 1 cm anal to the site of anastomosis. After oral administration of FT 0.6 g/day for 42 days, UFT 0.6 g/day was administered successively. As a result, complete tumor response was observed within about four months. UFT 0.3 approximately 0.6 g/day has been administered daily since then. The patient has been in good health without any sign of relapse for three years after achievement of the complete response.
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000601:surgery; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000601:surgery; D003131:Combined Modality Therapy; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000601:surgery; D012074:Remission Induction; D005641:Tegafur / Q000008:administration & dosage; D014498:Uracil / Q000008:administration & dosage
D005641:Tegafur; D014498:Uracil