title: [Basal serum production of gamma-interferon in subjects with gramineous allergic rhinosinusitis, in carriers of cancer of the larynx and in normal control subjects: study with specific monoclonal antibody. Preliminary data].
abstract: The authors report preliminary data about IF-gamma (Interferon-gamma) basal serum production tested by monoclonal antibody in three groups of 25 patients: alpha (normal controls), beta (ragweed hayfever patients) and gamma (laryngeal carcinoma patients pT3-4, pN0----3, pM0 by UICC). The IF-gamma mean value in ragweed hayfever patients is about five times higher then normal controls. These data are highly statistically significative. Moreover no value of IF-gamma basal serum production is tested in laryngeal carcinoma patients. The data are discussed.
mesh_terms: D000328:Adult; D000911:Antibodies, Monoclonal; D005260:Female; D006801:Humans; D007371:Interferon-gamma / Q000097:blood*; D007822:Laryngeal Neoplasms / Q000097:blood* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D006255:Rhinitis, Allergic, Seasonal / Q000097:blood* / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal; D007371:Interferon-gamma
vernacular_title: Studio della produzione sierica basale di interferon-gamma in soggetti affetti da rinosinusite allergica alle graminacee, in portatori di cancro della laringe ed in soggetti normali di controllo: ricerca con anticorpo monoclonale specifico. Dati preliminari.