Residual impairment in handgrip strength after unilateral frontal-lobe lesions.
The handgrip strength of 65 normal control subjects and 166 patients with unilateral frontal- or temporal-lobe excisions was assessed. Because of the known sex differences in strength, the results for the men and women were analysed separately. The grip strength of men with left frontal-lobe lesions was found to be within the normal range, but women with comparable excisions from the left frontal lobe had a residual impairment in strength on both hands. The men with right frontal-lobe lesions had a significant reduction in the strength of only the left hand, and the women in this group displayed a similar tendency. The deficits were interpreted in terms of a loss or disruption of input from the premotor area to the primary motor cortex.
D000293:Adolescent; D000328:Adult; D001931:Brain Mapping; D004292:Dominance, Cerebral / Q000502:physiology*; D004828:Epilepsies, Partial / Q000601:surgery; D005260:Female; D005625:Frontal Lobe / Q000502:physiology*; D006225:Hand / Q000294:innervation*; D006801:Humans; D007537:Isometric Contraction; D008297:Male; D008875:Middle Aged; D009044:Motor Cortex / Q000502:physiology; D009119:Muscle Contraction; D009132:Muscles / Q000294:innervation; D009434:Neural Pathways / Q000502:physiology; D011612:Psychosurgery; D013702:Temporal Lobe / Q000502:physiology