title: [Results of long-term treatment with depot neuroleptics in schizophrenic patients].
abstract: An examination was instituted to determine the effectiveness of maintenance therapy involving depot neuroplegics in out-patient after-care during an average follow-up of six years. At the time of examination, 172 patients treated with Depot-Lyogen showed statistically significant lower relapse and rehospitalisation rates, a reduction of the productive schizophrenic symptoms, and improved chance of rehabilitation, compared with 55 patients without treatment. In 22% of the 270 patients on Depot-Lyogen, there were early extrapyramidal side-effects, in 4.7% late dyskinesis, and in 4.3% depressive symptoms relating to medication. 35% of the patients did not receive consistent maintenance therapy. The improvement of after-care is discussed.
mesh_terms: D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005476:Fluphenazine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008134:Long-Term Care; D012559:Schizophrenia / Q000188:drug therapy*; D012565:Schizophrenic Psychology
chemical_list: C011825:fluphenazine depot; D005476:Fluphenazine
vernacular_title: Ergebnisse einer Langzeitbehandlung mit Depotneuroleptika bei Schizophrenen.