title: What is an antiandrogen and what is the physiological and pharmacological rationale for combined "castration" + "antiandrogen" therapy.
mesh_terms: D000726:Androgen Antagonists / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D002064:Buserelin / Q000494:pharmacology; D003131:Combined Modality Therapy; D006801:Humans; D007093:Imidazoles / Q000494:pharmacology; D048289:Imidazolidines; D008297:Male; D009919:Orchiectomy; D011471:Prostatic Neoplasms / Q000628:therapy*; D051381:Rats; D011987:Receptors, Steroid / Q000187:drug effects
chemical_list: D000726:Androgen Antagonists; D007093:Imidazoles; D048289:Imidazolidines; D011987:Receptors, Steroid; C021277:nilutamide; D002064:Buserelin