title: [Changes in CT findings in patients with liver metastases of breast cancer during effective intra-arterial infusion].
abstract: A study was done of the changes occurring in the CT findings of 12 cases in which liver metastases were found after radical mastectomy for breast cancer, as a result of intermittent low-dose hepatic arterial infusion chemotherapy using a reservoir, achieving PR. In four cases (33.3%) only shrinkage of the metastatic lesions was seen; in 3 others (25.0%), this was accompanied by irregularities in the margins of the liver surface; in the other 5 (41.7%), a high proportion of total, widespread compensatory deformity of the liver was observed. A tendency was noted for these changes to be more pronounced in cases in which the metastatic lesions occupied a large proportion of the liver. Hepatic degeneration appeared with a high frequency in cases where liver metastasis followed breast cancer, and it is considered that considerable care is necessary in evaluating the efficacy of treatment.
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D007260:Infusion Pumps; D007261:Infusions, Intra-Arterial; D008099:Liver / Q000000981:diagnostic imaging*; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000556:secondary; D008408:Mastectomy; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage; D011184:Postoperative Period; D005641:Tegafur / Q000008:administration & dosage; D014057:Tomography, X-Ray Computed; D014498:Uracil / Q000008:administration & dosage
chemical_list: D008937:Mitomycins; D005641:Tegafur; D016685:Mitomycin; D014498:Uracil; D004317:Doxorubicin