title: Surgical management of osteoradionecrosis of the temporal bone.
abstract: The surgical management of osteoradionecrosis of the temporal bone has met with limited success because of the difficulty in accurate assessment of the viability of nonnecrotic bone intraoperatively. Failure to resect all nonviable bone results in recurrence of a necrotic focus. With the use of hyperbaric oxygen therapy to stabilize marginal bone and oral tetracycline to label viable bone preoperatively, removal of all nonviable bone can be accomplished. Postoperatively, a second course of hyperbaric therapy enhances wound healing, thus assuring a successful outcome. This article details a successful systematic approach that was developed to resect a necrotic focus in the temporal bone of a 10-year-old boy who had undergone a full course of radiotherapy for treatment of a rhabdomyosarcoma.
mesh_terms: D002648:Child; D003131:Combined Modality Therapy; D006258:Head and Neck Neoplasms / Q000532:radiotherapy; D006801:Humans; D006931:Hyperbaric Oxygenation; D008297:Male; D010025:Osteoradionecrosis / Q000000981:diagnostic imaging / Q000601:surgery* / Q000628:therapy; D011182:Postoperative Care; D011292:Premedication; D011832:Radiation Injuries / Q000601:surgery*; D011859:Radiography; D013701:Temporal Bone / Q000000981:diagnostic imaging / Q000601:surgery*; D013752:Tetracycline / Q000008:administration & dosage
chemical_list: D013752:Tetracycline