[Histone-like nature of bacterial allergens used in diagnosing delayed hypersensitivity reaction].
In this work new data are presented on the comparative quantitative amino acid analysis of allergens, isolated and purified from different bacteria. On the basis of a high content of basic amino acids, such as lysine, arginine and histidine, in Mycobacterium, Brucella and Francisella tularensis allergens, a suggestion is made to classify bacterial allergens with histone-like proteins.
D000485:Allergens / Q000032:analysis* / Q000302:isolation & purification; D000596:Amino Acids / Q000032:analysis; D001426:Bacterial Proteins / Q000032:analysis* / Q000302:isolation & purification; D002003:Brucella abortus / Q000276:immunology; D005604:Francisella tularensis / Q000276:immunology; D006657:Histones / Q000032:analysis* / Q000302:isolation & purification; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000175:diagnosis* / Q000276:immunology; D009163:Mycobacterium bovis / Q000276:immunology; D012882:Skin Tests
D000485:Allergens; D000596:Amino Acids; D001426:Bacterial Proteins; D006657:Histones
Gistonpodobnaia priroda bakterial'nykh allergenov, ispol'zuemykh dlia diagnostiki v reaktsii giperchuvstvitel'nosti zamedlennogo tipa.