Selectivity of alterations in skeletal fibers in chronic Chagas' disease of the mouse.
In mice chronically infected with Trypanosoma cruzi, the masseter muscle (rich in type II fibers) was devoid of inflammatory infiltrates and parasites. In contrast, other muscles, composed of type I and II fibers, showed a decrease of type I fibers, parasites and lesions, suggesting that in T. cruzi infection type I muscle fibers are selectively damaged.
D000818:Animals; D014355:Chagas Disease / Q000473:pathology*; D005260:Female; D008406:Masseter Muscle / Q000473:pathology; D051379:Mice; D008807:Mice, Inbred BALB C; D009132:Muscles / Q000473:pathology*