title: [Factors contributing to the success of intracoronary thrombolytic therapy].
abstract: Intracoronary thrombolytic therapy (ICT) was used in 36 patients with acute transmural myocardial infarction. Recanalization of an infarction-dependent artery was achieved in 26 (72.2%) patients. Factors affecting the success of ICT were analysed, using Bayes' theorem. The ejection fraction (EF) is shown to have the highest predictive value as an indicator of left-ventricular pump function. The anticipated probability of ICT success is 84.9% in patients with acute myocardial infarction and a 35% EF baseline, and 25.7% in those with a 35% EF. In the absence of severe left-ventricular pumping and contractility disorders, the success of ICT is affected by patient's age, history of myocardial infarction and the site of thrombotic occlusion.
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001499:Bayes Theorem; D003327:Coronary Disease / Q000188:drug therapy*; D003328:Coronary Thrombosis / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000008:administration & dosage*; D011379:Prognosis; D013300:Streptokinase / Q000008:administration & dosage*; D014654:Vascular Patency / Q000187:drug effects
chemical_list: D013300:Streptokinase; D005996:Nitroglycerin
vernacular_title: Faktory, vliiaiushchie na uspekh intrakoronarnoĭ tromboliticheskoĭ terapii.