[Comparative studies of bronchial secretions in children with chronic, nontuberculous lung diseases. 2. The detection of IgA, sIgA, IgG, IgM and albumin].
The aim of the present study was to estimate some proteins in bronchial secretions from children with chronic nontuberculous lung diseases. In 166 samples from 63 children the immunoglobulins IgA, sIgA, IgG, IgM and albumin were measured. With rising deterioration of the state of the disease IgG, IgA and albumin were found to be increased, maximal values were observed in patients with dark altered mucosa. With increasing duration of the disease and in comparison with relapsing and deforming bronchitis IgA and sIgA are elevated in patients with chronic bronchitis. The other proteins had a decreasing tendency. In comparison with the later states of illness in sucklings with beginning of the lung disease IgA and sIgA could be estimated less frequently.
D000293:Adolescent; D000418:Albumins / Q000032:analysis*; D001980:Bronchi / Q000032:analysis* / Q000276:immunology / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D006801:Humans; D005779:Immunodiffusion; D007070:Immunoglobulin A / Q000032:analysis; D007071:Immunoglobulin A, Secretory / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D008171:Lung Diseases / Q000276:immunology*
D000418:Albumins; D007070:Immunoglobulin A; D007071:Immunoglobulin A, Secretory; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins
Vergleichende Bronchialsekretuntersuchungen bei Kindern mit chronischen, nichttuberkulösen Lungenerkrankungen. 2. Mitteilung: Zum Nachweis von IgA, sIgA, IgG, IgM und Albumin.