A grand mal seizure associated with desipramine and haloperidol.
Authors describe a case of grand mal seizure associated with administration of desipramine and haloperidol. Neuroleptic induced inhibition of desipramine metabolism is discussed as a possible explanation of unusually high desipramine plasma level of 610 ng/ml at the day of seizure.
D000328:Adult; D003891:Desipramine / Q000009:adverse effects* / Q000097:blood; D004347:Drug Interactions; D004359:Drug Therapy, Combination / Q000009:adverse effects; D004830:Epilepsy, Tonic-Clonic / Q000139:chemically induced*; D005260:Female; D006220:Haloperidol / Q000009:adverse effects*; D006801:Humans
D006220:Haloperidol; D003891:Desipramine