title: Computer-automated prediction of the mutagenicity of benzidine, 4,4"-diaminoterphenyl, 4-dimethylaminoazobenzene and 4-cyanodimethylaniline: comparison with the results of the Second UKEMS Collaborative Study.
abstract: There was agreement between the experimental results, obtained in the course of the Second UKEMS Collaborative Study, for the mutagenicity in Salmonella typhimurium of benzidine, 4,4"-diaminoterphenyl, 4-dimethylaminoazobenzene and 4-cyanodimethylaniline and the mutagenicity predicted by CASE (Computer Automated Structure Evaluation), a recently developed artificial intelligence system.
mesh_terms: D000814:Aniline Compounds / Q000009:adverse effects*; D001560:Benzidines / Q000009:adverse effects*; D012984:Software; D013730:Terphenyl Compounds / Q000009:adverse effects*; D004124:p-Dimethylaminoazobenzene / Q000009:adverse effects*
chemical_list: D000814:Aniline Compounds; D001560:Benzidines; D013730:Terphenyl Compounds; C029876:benzidine; C045996:4,4''-diaminoterphenyl; C042318:4-cyano-N,N-dimethylaniline; D004124:p-Dimethylaminoazobenzene