Early chorionic activity in women bearing inert IUD, copper IUD and levonorgestrel-releasing IUD.
Early chorionic activity was assessed in the premenstrual days by means of serum HCG beta-fraction. As control, a group of women with no contraceptive use was studied; early chorionic activity was detected in 31.8% of the cycles. In the group bearing an inert IUD the incidence was 20%, which did not differ from the control; while in the medicated IUD groups (Cu-IUD and LNG-IUD) the incidences were 4.8% and nil, respectively. Both medicated IUD groups showed a significant difference when compared with the control, as well as the inert IUD groups. The meaning of these findings, pointing out differences in the main mechanism of action between inert and medicated IUDs, is discussed.
D000328:Adult; D002823:Chorion / Q000187:drug effects*; D006063:Chorionic Gonadotropin / Q000097:blood*; D003271:Contraceptive Agents, Female / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007435:Intrauterine Devices, Copper / Q000009:adverse effects*; D007436:Intrauterine Devices, Medicated / Q000009:adverse effects*; D016912:Levonorgestrel; D009644:Norgestrel / Q000008:administration & dosage / Q000009:adverse effects*
D006063:Chorionic Gonadotropin; D003271:Contraceptive Agents, Female; D009644:Norgestrel; D016912:Levonorgestrel