Absence of antimycobacterial synergism between garlic extract and antituberculosis drugs.
Garlic extract inhibited the growth of four strains of Mycobacterium tuberculosis, three strains of Mycobacterium avium-intracellulare, and three strains of Mycobacterium kansasii in concentrations ranging from 0.98 mg/ml to 2.94 mg/ml. Synergism could not be demonstrated when garlic extract was added to various concentrations of four commonly used antituberculous drugs.
D000995:Antitubercular Agents / Q000494:pharmacology*; D004220:Disulfides; D004357:Drug Synergism; D005737:Garlic; D009161:Mycobacterium / Q000187:drug effects*; D009162:Mycobacterium avium / Q000187:drug effects; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D010946:Plants, Medicinal; D013441:Sulfinic Acids / Q000494:pharmacology
D000995:Antitubercular Agents; D004220:Disulfides; D013441:Sulfinic Acids; C006452:allicin