title: Microtubule-associated proteins present in different developmental stages of Drosophila melanogaster.
abstract: Microtubule-associated proteins (MAPs) have been isolated from different development stages of Drosophila melanogaster and characterized by their association to tubulin, but not to tubulin lacking its 4-kD carboxy terminal region (S-tubulin), and by their ability to promote tubulin polymerization. Following these criteria some peptides of Mr 255, 205, and 180 kD were identified as MAPs. By means of immunological analogy we have identified a peptide related to mammalian brain MAP known as tau factor.
mesh_terms: D000818:Animals; D001704:Biopolymers; D002846:Chromatography, Affinity; D002848:Chromatography, DEAE-Cellulose; D003429:Cross Reactions; D004258:DNA Polymerase III; D004331:Drosophila melanogaster / Q000032:analysis* / Q000254:growth & development; D004591:Electrophoresis, Polyacrylamide Gel; D007158:Immunologic Techniques; D008854:Microscopy, Electron; D008869:Microtubule-Associated Proteins / Q000032:analysis*; D008870:Microtubules / Q000648:ultrastructure; D011485:Protein Binding; D011863:Radioimmunoassay; D013552:Swine; D014157:Transcription Factors / Q000032:analysis; D014404:Tubulin / Q000378:metabolism
chemical_list: D001704:Biopolymers; D008869:Microtubule-Associated Proteins; D014157:Transcription Factors; D014404:Tubulin; C041273:transcription factor tau; D004258:DNA Polymerase III