title: Use of injectable collagen to treat chronic diabetic foot ulcers.
abstract: A significant portion of the population suffer from diabetic foot ulcers. While conservative treatment is often successful, many diabetic patients with accompanying peripheral vascular disease and neuropathy are under constant medical care for chronic, recurring foot ulcers. A new injectable biomaterial, Keragen Implant, was evaluated on two patients with bilateral diabetic ulcers. The implanted lesions healed completely during the months following treatment. Control lesions treated by conventional means remained open and ulcerated.
mesh_terms: D000328:Adult; D001672:Biocompatible Materials / Q000008:administration & dosage*; D002908:Chronic Disease; D003094:Collagen / Q000008:administration & dosage; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D005260:Female; D005534:Foot Diseases / Q000188:drug therapy* / Q000209:etiology; D005976:Glutaral / Q000008:administration & dosage; D006801:Humans; D007279:Injections, Subcutaneous; D008297:Male; D012883:Skin Ulcer / Q000188:drug therapy* / Q000209:etiology
chemical_list: D001672:Biocompatible Materials; C055485:Keragen implant; D003094:Collagen; D005976:Glutaral