Functional restoration of an articular surface using a heterotopic xenograft: biology of host-implant interactions in the canine patella.
Glutaraldehyde-treated bovine meniscal fibrocartilage has been used as a heterotopic bioprosthesis to repair large osteochondral defects in the canine patella. An efficient, functional articulating surface was reformed and the graft did not elicit a significant immunological response. Although tissue bonding between the host and graft was often excellent, the implant did not become revascularized or replaced by host tissue but acted as an inert space occupier. This material may offer some potential for conservative treatment of articular defects in the patella in appropriate circumstances.
D000818:Animals; D001705:Bioprosthesis; D001847:Bone Diseases / Q000473:pathology / Q000601:surgery*; D002358:Cartilage, Articular / Q000473:pathology; D002417:Cattle; D003432:Cross-Linking Reagents; D004285:Dogs; D005260:Female; D005976:Glutaral; D008297:Male; D008592:Menisci, Tibial / Q000637:transplantation*; D010329:Patella / Q000473:pathology
D003432:Cross-Linking Reagents; D005976:Glutaral