Intractable bladder hemorrhage requiring cystectomy after use of intravesical thiotepa.
A case of nearly exsanguinating bladder hemorrhage, occurring six months after intravesical thiotepa administration, is reported. The hemorrhage was not attributable to myelosuppression. This case also demonstrates the hazard of using formalin to control such hemorrhage.
D000283:Administration, Intravesical; D000368:Aged; D002291:Carcinoma, Papillary / Q000188:drug therapy*; D006470:Hemorrhage / Q000139:chemically induced*; D006801:Humans; D008297:Male; D013852:Thiotepa / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D001743:Urinary Bladder / Q000601:surgery; D001745:Urinary Bladder Diseases / Q000139:chemically induced* / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy*
D013852:Thiotepa