title: [Method of determining the antibiotic concentration in biological material].
abstract: To lower the role of natural antibacterial activity of biological substrates from humans and laboratory animals in microbiological assay of bleomycin (bleomycin) with B. subtilis ATCC 6633 as the test-microbe, it was suggested to increase the procedure sensitivity by using the medium modification. In determining concentrations of aminoglycosides by the agar diffusion method the use of B. pumilus NCTC 8241 as the test-microbe is recommended.
mesh_terms: D000362:Agar; D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis* / Q000493:pharmacokinetics; D001407:Bacillus / Q000378:metabolism; D001412:Bacillus subtilis / Q000378:metabolism; D001681:Biological Assay / Q000379:methods*; D003470:Culture Media; D004058:Diffusion; D006801:Humans; D009176:Mycoplasma mycoides / Q000378:metabolism; D013696:Temperature
chemical_list: D000900:Anti-Bacterial Agents; D003470:Culture Media; D000362:Agar
vernacular_title: K metodike opredeleniia kontsentratsii nekotorykh antibiotikov v biologicheskom materiale.