Rett's syndrome with Lennox-Gastaut pattern.
Three Latin American female patients studied in two different centers (Mexico City and Houston, Texas) had the clinical criteria of Rett's Syndrome, including progressive intellectual deterioration, stereotyped movements, loss of purposeful hand use, ataxia, and progressive disability. The three patients had normal laboratory studies including imaging studies (CT and MRI) but consistently abnormal EEGs with Lennox-Gastaut pattern. The usefulness of the EEG in the differential diagnosis and the association of this electrographic phenomenon are stressed.
D001321:Autistic Disorder / Q000175:diagnosis* / Q000235:genetics; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000175:diagnosis* / Q000235:genetics; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D009468:Neuromuscular Diseases / Q000175:diagnosis* / Q000235:genetics; D013577:Syndrome