[Effect of glutathione on the course of radiation sickness with a marked gastrointestinal syndrome and the effectiveness of parenteral feeding in an experiment].
Injections of oxidized glutathione (40 mg/kg, 5-7 days) combined with the parenteral nutrition (PN) of rats after local X-irradiation of abdomen (13-14.5 Gy) increased significantly the survival rate, decreased the gastrointestinal syndrome manifestations, and intensified the assimilation of a PF amino acid component. The reduced glutathione had no effect.
D000208:Acute Disease; D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D005767:Gastrointestinal Diseases / Q000209:etiology / Q000378:metabolism / Q000628:therapy; D005978:Glutathione / Q000378:metabolism / Q000627:therapeutic use*; D008297:Male; D009584:Nitrogen / Q000378:metabolism; D010084:Oxidation-Reduction; D010288:Parenteral Nutrition; D011833:Radiation Injuries, Experimental / Q000150:complications / Q000378:metabolism / Q000401:mortality / Q000628:therapy*; D051381:Rats; D011919:Rats, Inbred Strains
D000596:Amino Acids; D005978:Glutathione; D009584:Nitrogen
Vliianie glutationa na techenie luchevoĭ bolezni s vyrazhennym zheludochno-kishechnym sindromom i na éffektivnost' parenteral'nogo lecheniia v éksperimente.