[Met]enkephalin-Arg6-Phe7 in human CSE--increased levels in late pregnancy.
The opioid heptapeptide, [Met]enkephalin-Arg6-Phe7 was measured in CSF of women at term pregnancy and during the luteal phase by RIA. Levels turned out to be significantly increased in pregnant women. These results are in agreement with an earlier paper in which we reported increased levels of receptorassayed opioid peptides deriving from proenkephalin A in CSF of women in term pregnancy compared to levels in nonpregnant, nonpuerperal women.
D002851:Chromatography, High Pressure Liquid; D004744:Enkephalin, Methionine / Q000031:analogs & derivatives* / Q000134:cerebrospinal fluid; D005260:Female; D006801:Humans; D008183:Luteal Phase; D011247:Pregnancy / Q000134:cerebrospinal fluid*; D011263:Pregnancy Trimester, Third; D011863:Radioimmunoassay; D012016:Reference Values
D004744:Enkephalin, Methionine; C027511:enkephalin-Met, Arg(6)-Phe(7)-