Cross reactivity between Trypanosoma cruzi and Leishmania antigens in the lymphocyte blastogenesis assay.
The in vitro blastogenesis response of lymphocytes from 19 patients, with either visceral or mucocutaneous leishmaniasis or Chagas disease, to antigens of the Leishmania-Trypanosoma complex was studied. Cells from all patients responded to both homologous and heterologous antigens and the magnitude of the responses did not differ for any of the patient groups or antigens.
D000293:Adolescent; D000328:Adult; D000818:Animals; D000953:Antigens, Protozoan / Q000276:immunology*; D014355:Chagas Disease / Q000276:immunology; D002648:Child; D003429:Cross Reactions; D006801:Humans; D007891:Leishmania / Q000276:immunology*; D007893:Leishmania donovani / Q000276:immunology; D007894:Leishmania mexicana / Q000276:immunology; D007896:Leishmaniasis / Q000276:immunology; D007898:Leishmaniasis, Visceral / Q000276:immunology; D008213:Lymphocyte Activation; D008875:Middle Aged; D014349:Trypanosoma cruzi / Q000276:immunology*
D000953:Antigens, Protozoan