title: ABH and Lewis antigen and antibody expression after bone marrow transplantation.
abstract: We have tested 10 bone marrow transplant donors and recipients for ABH and Lewis antigens and ABH antibodies. Two group A2 recipients stably engrafted with group O marrow produced anti-A1. Small quantities of recipient-type ABH substance were found on the posttransplant erythrocytes in cases where the recipient was a secretor but not in a single nonsecretor recipient. Lewis antigens were always of recipient type. The incidence of graft-versus-host disease and graft rejection were similar in 41 patients who received ABO-mismatched and 61 patients who received ABO-matched grafts.
mesh_terms: D000017:ABO Blood-Group System / Q000276:immunology*; D000293:Adolescent; D000328:Adult; D001787:Blood Group Incompatibility / Q000276:immunology; D016026:Bone Marrow Transplantation; D002648:Child; D002675:Child, Preschool; D006084:Graft Rejection; D006086:Graft vs Host Disease / Q000209:etiology; D006801:Humans; D007223:Infant; D007983:Lewis Blood Group Antigens / Q000276:immunology*; D011184:Postoperative Period
chemical_list: D000017:ABO Blood-Group System; D007983:Lewis Blood Group Antigens