Bacteriological and serological aspects of group A streptococcal pharyngotonsillitis caused by group A streptococci.
Several bacteriological and serological variables were studied in connection with a clinical treatment trial in 212 patients with group A streptococcal pharyngotonsillitis. Anaerobic incubation was not superior to incubation in 5% CO2 in air for the detection of group A streptococci. Saliva cultures were inferior to conventional throat cultures in detecting group A streptococci. No strains from patients with recurrences were found to be tolerant to penicillin. In several patients (all asymptomatic), group C and G streptococci were found in follow-up cultures. Group A streptococci serology was more often positive after two months than after one month, also in patients without recurrence.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000989:Antistreptolysin / Q000032:analysis; D001426:Bacterial Proteins; D002434:Cefadroxil / Q000627:therapeutic use; D002648:Child; D003851:Deoxyribonucleases / Q000276:immunology; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D010404:Penicillin V / Q000627:therapeutic use; D010612:Pharyngitis / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D010614:Pharynx / Q000382:microbiology; D012008:Recurrence; D012463:Saliva / Q000382:microbiology; D013290:Streptococcal Infections / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000276:immunology / Q000302:isolation & purification; D013301:Streptolysins / Q000276:immunology; D014069:Tonsillitis / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology
D001426:Bacterial Proteins; D013301:Streptolysins; C025964:streptolysin O; D002434:Cefadroxil; D000989:Antistreptolysin; D003851:Deoxyribonucleases; C020069:deoxyribonuclease B; D010404:Penicillin V