Fetal lung to liver reflectivity ratio and lung maturity.
A pilot study examined 23 patients who underwent simultaneous ultrasound and amniocentesis to determine whether the ratio of densitometrically determined tissue densities of fetal lung and liver correlate with the L/S, the OD 650, or phosphatidylglycerol levels. The incidence of a lung/liver ratio greater than 1 of 65% was similar to that of maturity levels of the standard tests. However, there was no statistically significant correlation between an L/L greater than 1 and/or any maturity parameter tested, nor was there any correlation with the absence of pulmonary maturity. We conclude that this test cannot be reliably used to predict L/S, OD 650 reading, or PG levels.
D005260:Female; D005325:Fetal Organ Maturity; D006801:Humans; D008099:Liver / Q000196:embryology*; D008168:Lung / Q000196:embryology*; D010713:Phosphatidylcholines / Q000032:analysis; D010715:Phosphatidylglycerols / Q000032:analysis; D010865:Pilot Projects; D011237:Predictive Value of Tests; D011247:Pregnancy; D013109:Sphingomyelins / Q000032:analysis; D014463:Ultrasonography
D010713:Phosphatidylcholines; D010715:Phosphatidylglycerols; D013109:Sphingomyelins