[Effect of piracetam on the functional activity of the brain in patients with craniocerebral injuries].
Repetitive EEG spectral analysis in 32 patients after severe of mild head trauma revealed two types of responses to Piracetam evidencing the ambiguity of its effect on unspecific activating brain structures. Besides the brain cortex, the hypothalamo-thalamic system was found to participate in the response. With epileptoid signs present in the EEG, the drug could reduce the seizure threshold.
D001921:Brain / Q000187:drug effects* / Q000503:physiopathology; D001930:Brain Injuries / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D004341:Drug Evaluation; D004569:Electroencephalography / Q000379:methods; D004834:Epilepsy, Post-Traumatic / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D010889:Piracetam / Q000627:therapeutic use*; D011760:Pyrrolidinones / Q000627:therapeutic use*
D011760:Pyrrolidinones; D010889:Piracetam
Vliianie piratsetama na funktsional'nuiu aktivnost' golovnogo mozga u bol'nykh s cherepno-mozgovoĭ travmoĭ.