Evidence for the presence of cytosolic inhibitors for phospholipid/Ca2+-dependent protein kinase in mastocytoma cell.
1. Two kinds of C-kinase inhibitors were indicated to be present in mastocytoma cells. 2. One is a protein (mol. wt 64,000) which is weak but specific for C-kinase. 3. The other component (mol. wt 23,000) does not seem to be a protein and inhibits A-kinase as well as C-kinase.
D000818:Animals; D001921:Brain / Q000201:enzymology; D002460:Cell Line; D004791:Enzyme Inhibitors / Q000302:isolation & purification* / Q000494:pharmacology; D007700:Kinetics; D012515:Mast-Cell Sarcoma / Q000032:analysis*; D051379:Mice; D008970:Molecular Weight; D009363:Neoplasm Proteins / Q000302:isolation & purification; D011493:Protein Kinase C / Q000037:antagonists & inhibitors*; D051381:Rats
D004791:Enzyme Inhibitors; D009363:Neoplasm Proteins; D011493:Protein Kinase C