[Enhancement of Walker-256 antitumor effect by intra-arterial administration of TNF before using mitomycin C].
Intraarterial administration of TNF showed enhanced antitumor effects on Walker-256 implanted in the dorsum side of the Wistar rat hindpaw than by its intravenous injection. Using MMC immediate after TNF can have an improved antitumor effects.
D000818:Animals; D002279:Carcinoma 256, Walker / Q000188:drug therapy / Q000473:pathology / Q000628:therapy*; D004357:Drug Synergism; D007275:Injections, Intravenous; D008297:Male; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage / Q000627:therapeutic use*; D051381:Rats; D011919:Rats, Inbred Strains; D014409:Tumor Necrosis Factor-alpha / Q000008:administration & dosage* / Q000627:therapeutic use
D008937:Mitomycins; D014409:Tumor Necrosis Factor-alpha; D016685:Mitomycin