title: Successful combined medical and surgical treatment of a lower extremity sclerodermal ulcer.
abstract: Combined medical and surgical treatment of a chronic lower extremity ulcer in a patient with systemic scleroderma is described. Recent pharmacological advances including calcium channel blockers, meticulous surgical care, and skin grafting offer promise for more consistent wound closure in sclerodermal skin ulcerations.
mesh_terms: D000368:Aged; D001241:Aspirin / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003646:Debridement; D004176:Dipyridamole / Q000627:therapeutic use; D012968:Etidronic Acid / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000209:etiology / Q000628:therapy*; D009543:Nifedipine / Q000627:therapeutic use; D012595:Scleroderma, Systemic / Q000150:complications*; D016038:Skin Transplantation; D014945:Wound Healing
chemical_list: D004176:Dipyridamole; D009543:Nifedipine; D012968:Etidronic Acid; D001241:Aspirin