Pulmonary complications of hormone treatment in prostate carcinoma.
Fever, dyspnea, dry cough and interstitial fibrosis occurred in a man with prostate carcinoma treated with nilutamide and buserelin for two and one-half months. The diagnosis of drug-induced fibrosis was established on the basis of chronologic and semiologic events. This is the first such case reported.
D000230:Adenocarcinoma / Q000188:drug therapy*; D000368:Aged; D000726:Androgen Antagonists / Q000009:adverse effects* / Q000627:therapeutic use; D002064:Buserelin / Q000009:adverse effects* / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D007093:Imidazoles / Q000009:adverse effects* / Q000627:therapeutic use; D048289:Imidazolidines; D008297:Male; D011471:Prostatic Neoplasms / Q000188:drug therapy*; D011658:Pulmonary Fibrosis / Q000139:chemically induced*
D000726:Androgen Antagonists; D007093:Imidazoles; D048289:Imidazolidines; C021277:nilutamide; D002064:Buserelin