title: DNA sequence analysis of X-ray-induced deletions at the white locus of Drosophila melanogaster.
abstract: We have determined the nucleotide sequence of 5 X-ray-induced white mutants containing small rearrangements. Comparison with wild-type sequences showed deletions in the coding region ranging in size between 6 bp and 29 bp. These small deletions are distributed non-randomly over the white locus. Two mutants contain the same 29-bp deletion, while the other 3 deletions are clustered. All 5 deletions have occurred between 2 and 3 bp repeats. One of the repeats is preserved in the novel junction formed by the deletion. Our results suggest that recombinational processes may be involved in the generation of X-ray-induced deletions.
mesh_terms: D000818:Animals; D001483:Base Sequence; D002872:Chromosome Deletion; D003001:Cloning, Molecular; D004331:Drosophila melanogaster / Q000235:genetics*; D009154:Mutation / Q000528:radiation effects*; D010858:Pigmentation; D011995:Recombination, Genetic / Q000528:radiation effects*; D014965:X-Rays