title: The molecular genetics of C1 utilizing microorganisms. An overview.
abstract: The availability of recombinant DNA techniques has enabled the successful genetic analysis and manipulation of a range of C1 utilizing microorganisms. It has resulted in the identification of genes of interest on both plasmids and the chromosome; enabled the linkage of chromosomal genes to be determined; established the function and regulatory patterns of genes essential for utilization of C1 compounds and provided information on the evolution of methanogenic bacteria.
mesh_terms: D001419:Bacteria / Q000235:genetics* / Q000378:metabolism; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D019605:Euryarchaeota / Q000235:genetics / Q000378:metabolism; D005798:Genes, Bacterial; D005816:Genetic Complementation Test; D008697:Methane / Q000378:metabolism*; D008772:Methylococcaceae / Q000235:genetics* / Q000378:metabolism; D009154:Mutation
chemical_list: D008697:Methane