[Consequences of ischemia of the terminal ileum in the rat: influence of exclusive parenteral nutrition].
An experimental model of ischemia of the distal part of the small intestine has been realized in rats. This experimental study realizes a moderate ischemia of the distal part of ileum loops, by vascular ligations. An important decreasing of the intestinal motility is observed 2 days after the operation, by in vitro study. The motility became normal 7 days after. During this time a microbiological evaluation revealed an important increasing of anaerobic germ in the distal ileum. Total parenteral nutrition preserves the intestinal motility and the endoluminal flora. Ischemia of the small bowel is an important component of enterocolitis by modification of the peristalsis. The total Parenteral Nutrition in such condition seems to protect the intestinal flora.
D000818:Animals; D004761:Enterocolitis, Pseudomembranous / Q000601:surgery; D005260:Female; D007082:Ileum / Q000098:blood supply* / Q000503:physiopathology / Q000601:surgery; D007421:Intestine, Small / Q000382:microbiology; D007511:Ischemia / Q000503:physiopathology*; D008297:Male; D009119:Muscle Contraction; D009130:Muscle, Smooth / Q000503:physiopathology; D010289:Parenteral Nutrition, Total; D051381:Rats; D011919:Rats, Inbred Strains
Conséquences de l'ischémie de l'ileon terminal chez le rat: influence de la nutrition parentérale exclusive.