title: [Effect of space flight factors on the blood circulation function in primates].
abstract: Using radioactive isotopes, central, peripheral and organ blood circulation was investigated in two rhesus-monkeys before the 7-day space flight, 1.5 hours after touchdown, and 4 months after recovery. Blood distribution and shifts were measured in different body segments, viz. head, chest, abdomen, legs. Postflight measurements revealed a decrease of plasma and blood volume. They also demonstrated changes in cardiac output and stroke volume, decrease of total peripheral resistance, reduction of mean arterial pressure and a slight increase of heart rate. Pulmonary blood flow velocity and time varied insignificantly and in a different manner. Blood was pooled in the legs. Blood flow velocity in the skin of the upper and lower body decreased while in muscles it increased above the baseline values. Postflight, muscles acted as a hemodynamic blood pool. The tolerance of both monkeys to the tilt test was satisfactory. It can be concluded that the monkeys tolerated the 7-day space flight well enough.
mesh_terms: D000818:Animals; D001775:Blood Circulation; D001810:Blood Volume; D000882:Haplorhini / Q000502:physiology*; D006439:Hemodynamics; D011865:Radioisotope Dilution Technique; D013026:Space Flight; D013997:Time Factors; D014586:USSR
vernacular_title: Vliianie faktorov kosmicheskogo poleta na sostoianie gemotsirkuliatsii u primatov.