Interspecies cross-reactivity of bovine lymphocytotoxic sera with pig lymphocytes.
Forty-three bovine BoLA antisera were tested on pig lymphocytes by a microlymphocytotoxicity test. Twenty-five were found to be cytolytic. Fifteen sera detected the A blood group antigen on porcine lymphocytes but showed no reaction with the J antigen on bovine lymphocytes. Six BoLA reagents reacted with all pig cells tested. Cross-reactions with SLA antigens were observed in only four sera, the highest correlation being recorded with SLA-W7 (r = 0.87). Bovine alloantisera are not of value for SLA typing.
D000818:Animals; D000961:Antilymphocyte Serum / Q000276:immunology*; D002417:Cattle / Q000276:immunology*; D003429:Cross Reactions; D003601:Cytotoxicity Tests, Immunologic; D006649:Histocompatibility Antigens / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology; D013045:Species Specificity; D013552:Swine / Q000276:immunology*
D000961:Antilymphocyte Serum; D006649:Histocompatibility Antigens