Pre-ALL and non-A, non-B hepatitis infection.
We report a case of acute lymphoblastic leukaemia which presented as hypoplastic anaemia following Non-A, Non-B viral hepatitis infection. The role of infection and the mechanisms involved in the evolution of pre-ALL to overt leukaemia remain speculative. However, it is of practical importance to distinguish pre-ALL from aplastic anaemia and the myelodysplastic syndromes during the early pancytopenic phase to avoid inappropriate management.
D000741:Anemia, Aplastic / Q000175:diagnosis; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006526:Hepatitis C / Q000150:complications*; D006525:Hepatitis, Viral, Human / Q000150:complications*; D006801:Humans; D010198:Pancytopenia / Q000175:diagnosis / Q000209:etiology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000175:diagnosis*; D011289:Preleukemia / Q000150:complications* / Q000175:diagnosis; D018805:Sepsis / Q000150:complications