title: The Escherichia coli K-12 lexA2 gene encodes a hypocleavable repressor.
abstract: LexA2 repressor was partially inactivated after mitomycin C or UV light treatment in a recA+ or recA85(Prtc) (protease constitutive) host background. LexA2 protein was cleaved, but the reaction was slower than that observed for LexA+ repressor. lexA2 had a C-to-T transition at nucleotide 461 (Thr-154 to Ile).
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics* / Q000528:radiation effects; D005786:Gene Expression Regulation; D005798:Genes, Bacterial; D016685:Mitomycin; D008937:Mitomycins / Q000494:pharmacology; D009154:Mutation; D012097:Repressor Proteins / Q000235:genetics* / Q000378:metabolism; D013014:SOS Response, Genetics; D012697:Serine Endopeptidases; D014157:Transcription Factors / Q000235:genetics*; D014466:Ultraviolet Rays; D000099160:LexA Repressor Protein
chemical_list: D001426:Bacterial Proteins; D016685:Mitomycin; D008937:Mitomycins; D012097:Repressor Proteins; D012697:Serine Endopeptidases; D014157:Transcription Factors; D000099160:LexA Repressor Protein