Plasma glucose and insulin levels in women using a levonorgestrel-containing triphasic oral contraceptive for three months.
Plasma glucose and insulin levels were measured for three hours after an oral glucose challenge in twenty-nine women before and after using a triphasic oral contraceptive containing ethinyl estradiol and levonorgestrel for three months. There were significant elevations in the glucose levels during the three-month tolerance test, while the insulin levels were unchanged. These data suggest that this OC can alter carbohydrate metabolism and that long-term studies are needed to assess the extent of this metabolic change.
D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D003277:Contraceptives, Oral, Combined / Q000008:administration & dosage*; D004997:Ethinyl Estradiol / Q000008:administration & dosage*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000097:blood*; D016912:Levonorgestrel; D009644:Norgestrel / Q000008:administration & dosage*; D011446:Prospective Studies
D001786:Blood Glucose; D003277:Contraceptives, Oral, Combined; D007328:Insulin; D009644:Norgestrel; D004997:Ethinyl Estradiol; D016912:Levonorgestrel