Sneddon's syndrome: an antiphospholipid antibody syndrome?
A 44-year-old woman with livedo reticularis, multiple ischemic strokes, and transient ischemic attacks (Sneddon's syndrome) had antiphospholipid antibodies--the lupus anticoagulant and anticardiolipin antibodies. This patient provides support for the hypothesis that these antibodies are involved in the pathogenesis of this rare but now potentially treatable disorder.
D000906:Antibodies / Q000032:analysis / Q000276:immunology*; D001241:Aspirin / Q000627:therapeutic use; D001779:Blood Coagulation Factors / Q000032:analysis / Q000276:immunology; D002308:Cardiolipins / Q000276:immunology; D002544:Cerebral Infarction / Q000150:complications* / Q000000981:diagnostic imaging / Q000276:immunology; D004176:Dipyridamole / Q000627:therapeutic use; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000150:complications* / Q000000981:diagnostic imaging / Q000276:immunology; D016682:Lupus Coagulation Inhibitor; D008875:Middle Aged; D010743:Phospholipids / Q000276:immunology*; D012871:Skin Diseases / Q000150:complications* / Q000276:immunology; D013577:Syndrome; D014057:Tomography, X-Ray Computed
D000906:Antibodies; D001779:Blood Coagulation Factors; D002308:Cardiolipins; D016682:Lupus Coagulation Inhibitor; D010743:Phospholipids; D004176:Dipyridamole; D001241:Aspirin