Comparison between prochymosin and pepsinogen from lamb and calf.
1. Prochymosin (EC 3.4.23.4) and pepsinogen A (EC 3.4.23.1) from Mongolian lamb (Ovis platyurea) were purified to homogeneity by salt precipitation, gel filtration and ion-exchange chromatography. 2. Immunoelectrophoresis shows partial immunochemical identity between chymosins and pepsins from lamb and cattle, respectively. 2. Activity determinations, N-terminal amino acid sequences and amino acid compositions also show a close relationship between the proteinases from lamb and cattle. 4. Lamb prochymosin and pepsinogen are both glycosylated.
D000595:Amino Acid Sequence; D000818:Animals; D002417:Cattle; D012085:Chymosin / Q000378:metabolism*; D004792:Enzyme Precursors / Q000378:metabolism*; D006031:Glycosylation; D007122:Immunoelectrophoresis; D008969:Molecular Sequence Data; D010435:Pepsinogens / Q000378:metabolism*; D012756:Sheep; D013552:Swine
D004792:Enzyme Precursors; D010435:Pepsinogens; C032443:prorennin; D012085:Chymosin