Evaluation of coagulase-negative staphylococci for ability to produce toxic shock syndrome toxin 1.
A large and diverse group of coagulase-negative staphylococci were assayed for the ability to produce toxic shock syndrome toxin 1 (TSST-1) by immunological reactivity, and whole-cell DNAs from 33 of these strains were hybridized with a TSST-1-specific gene probe. None of the strains tested, including isolates that have been reported as TSST-1+, produced the exotoxin, and no DNA homology was found with the gene probe.
D001427:Bacterial Toxins; D003030:Coagulase / Q000378:metabolism; D004269:DNA, Bacterial / Q000032:analysis*; D004768:Enterotoxins / Q000096:biosynthesis* / Q000235:genetics; D005779:Immunodiffusion; D009693:Nucleic Acid Hybridization; D012689:Sequence Homology, Nucleic Acid; D013211:Staphylococcus aureus / Q000201:enzymology / Q000235:genetics / Q000378:metabolism*; D018089:Superantigens
D001427:Bacterial Toxins; D003030:Coagulase; D004269:DNA, Bacterial; D004768:Enterotoxins; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal