title: [The effect of vitamin A on trypsin inhibition activity of the blood and cervical mucus after the effects of hormones on the ovaries of sheep in the estrus period].
abstract: Vitamin A (50,000 I. U.), administered after oestrus synchronization by PGF2 alpha (2 X 125 micrograms; 1st and 11th day) together with PMSG (750 and 1000 I. U.), had a stronger influence on the changes in the trypsin-inhibition activities (TIA) of the blood plasma, as compared with the effect of PMSG. The changes in the average TIA values within 120 hours after the administration of the stimulating dose were also observed more frequently to depend on vitamin A. After administration of 1000 I. U. PMSG, an increase was recorded only in the values of the fraction of low-molecular TIA, whereas the administration of the combinations of PMSG + vitamin A resulted in an increase of all the TIA's under study. This increase was directly correlated with an increased number of non-atretic tertiary follicles, with an increased number of ovulations (at the same dose of PMSG), and with a reduced ratio of changes in the concentration of progesterone (P) and 17-beta oestradiol (E): P/E = 1.1 after the administration of 1000 I. U. PMSG, P/E = 0.81 after I. U. PMSG + vitamin A, and P/E = 0.90 after 1000 I. U. PMSG + vitamin A. The increase in the average TIA of the cervical mucus is due to the increased secretory activity of the cervical glands rather than to the multiplication of these glands after ovary stimulation.
mesh_terms: D000818:Animals; D002582:Cervix Mucus / Q000378:metabolism; D015237:Dinoprost; D004958:Estradiol / Q000097:blood; D004971:Estrus / Q000378:metabolism*; D005260:Female; D006064:Gonadotropins, Equine / Q000494:pharmacology*; D010053:Ovary / Q000187:drug effects*; D011374:Progesterone / Q000097:blood; D011460:Prostaglandins F / Q000494:pharmacology; D012756:Sheep / Q000378:metabolism*; D014361:Trypsin Inhibitors / Q000097:blood / Q000378:metabolism*; D014801:Vitamin A / Q000494:pharmacology*
chemical_list: D006064:Gonadotropins, Equine; D011460:Prostaglandins F; D014361:Trypsin Inhibitors; D014801:Vitamin A; D011374:Progesterone; D004958:Estradiol; D015237:Dinoprost
vernacular_title: Vplyv vitamínu A na trypsín inhibicné aktivity (TIA) krvnej plazmy a cervikálneho hlienu po hormonálnom ovplyvnení ovárií oviec v estrickom období.