Randomised controlled trials of phenobarbitone and valproate in febrile convulsions.
Results from British trials of phenobarbitone and valproate for the prophylactic treatment of febrile convulsions were pooled and analysed on an intention to treat basis. The overall odds ratio for phenobarbitone was 0.8 and for valproate 1.42. Neither result was significant. Neither treatment can be recommended in the light of experience.
D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D006801:Humans; D007223:Infant; D010634:Phenobarbital / Q000627:therapeutic use*; D011897:Random Allocation; D012008:Recurrence; D003294:Seizures, Febrile / Q000517:prevention & control*; D014635:Valproic Acid / Q000627:therapeutic use*
D014635:Valproic Acid; D010634:Phenobarbital