Functional blocking of the interleukin-2 receptor (IL-2R) may be important in the efficacy of IL-2R antibody therapy.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D000936:Antigen-Antibody Complex; D006085:Graft Survival; D016027:Heart Transplantation; D007165:Immunosuppression Therapy / Q000379:methods; D007376:Interleukin-2 / Q000378:metabolism; D007518:Isoantibodies / Q000627:therapeutic use*; D008213:Lymphocyte Activation; D051381:Rats; D011919:Rats, Inbred Strains; D011971:Receptors, Immunologic / Q000276:immunology* / Q000378:metabolism; D015375:Receptors, Interleukin-2; D013997:Time Factors
D000911:Antibodies, Monoclonal; D000936:Antigen-Antibody Complex; D007376:Interleukin-2; D007518:Isoantibodies; D011971:Receptors, Immunologic; D015375:Receptors, Interleukin-2