title: Subtypes in major depression without melancholia.
abstract: Using the Diagnostic and Statistical Manual of Mental Disorders (DSM III, 1980) criteria to diagnose major depression without melancholia, 70 adult patients were selected for further detailed clinical and neuro-endocrinological evaluation. Two subtypes emerged; changes in sleeping patterns, body mass and thyrotrophin response to thyrotrophin-releasing hormone constituted the distinguishing features between the two categories (P = 0.012).
mesh_terms: D000328:Adult; D000367:Age Factors; D003866:Depressive Disorder / Q000145:classification* / Q000175:diagnosis; D003907:Dexamethasone; D001068:Feeding and Eating Disorders / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D012893:Sleep Wake Disorders / Q000150:complications; D013973:Thyrotropin-Releasing Hormone
chemical_list: D013973:Thyrotropin-Releasing Hormone; D003907:Dexamethasone