title: Light chain cardiomyopathy associated with small-vessel disease.
abstract: Intramyocardial small-vessel disease associated with systemic light chain deposition is a rare condition that may occur in patients with monoclonal plasma cell proliferation. This article describes a 39-year-old woman who had experienced several episodes of subendocardial myocardial infarction and was found to have plasma cell dyscrasia. Endomyocardial biopsy revealed kappa light chain deposits along the sarcolemmal and vascular basement membranes, the latter of which resulted in vascular occlusion and myocardial infarction. Postmortem examination showed polyvisceral deposition of kappa light chains. This rare complication of plasma cell proliferative process has a poor prognosis.
mesh_terms: D000328:Adult; D001157:Arterial Occlusive Diseases / Q000209:etiology* / Q000473:pathology; D003331:Coronary Vessels / Q000473:pathology; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications*; D007147:Immunoglobulin Light Chains; D009203:Myocardial Infarction / Q000209:etiology / Q000473:pathology
chemical_list: D007147:Immunoglobulin Light Chains