title: Inhibition of muscular amino acid release by lipid infusion in man.
abstract: Amino acid balances of healthy postabsorptive volunteers were investigated with the forearm technique under the influence of an intravenous infusion of triglyceride emulsions (LCT; MCT/LCT) [corrected]. A decrease of the basal muscular release of most of the amino acids, respectively an increase of pre-existent uptake rates [corrected]. In parallel, arterial concentrations of these amino acids declined. With constant insulin levels and substantially unchanged blood glucose levels, this inhibition of muscular proteolysis and/or stimulation of proteosynthesis is most probably due to the increased level of free fatty acids.
mesh_terms: D000596:Amino Acids / Q000097:blood / Q000378:metabolism*; D001786:Blood Glucose / Q000378:metabolism; D005217:Fat Emulsions, Intravenous / Q000494:pharmacology*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D006801:Humans; D009132:Muscles / Q000187:drug effects* / Q000378:metabolism; D014280:Triglycerides / Q000097:blood
chemical_list: D000596:Amino Acids; D001786:Blood Glucose; D005217:Fat Emulsions, Intravenous; D005230:Fatty Acids, Nonesterified; D014280:Triglycerides