An association between schistosomes and contrapsin, a mouse serine protease inhibitor (serpin).
An antigen in homogenates of adult Schistosoma mansoni worms grown in mice, and immunoprecipitated by polyspecific rabbit antiserum, has been identified as contrapsin, a mouse serine protease inhibitor (serpin). In the serum of some mice infected with S. mansoni contrapsin was found with altered immunoelectrophoretic characteristics when compared with contrapsin from uninfected mice.
D000818:Animals; D000947:Antigens, Helminth / Q000032:analysis*; D002850:Chromatography, Gel; D006224:Cricetinae; D004591:Electrophoresis, Polyacrylamide Gel; D007122:Immunoelectrophoresis; D007123:Immunoelectrophoresis, Two-Dimensional; D051379:Mice; D008970:Molecular Weight; D009115:Muridae; D011817:Rabbits; D012550:Schistosoma mansoni / Q000276:immunology*; D012555:Schistosomiasis mansoni / Q000097:blood / Q000469:parasitology; D015843:Serpins; D014361:Trypsin Inhibitors / Q000032:analysis* / Q000276:immunology
D000947:Antigens, Helminth; D015843:Serpins; D014361:Trypsin Inhibitors; C033691:contrapsin