[Atypical muscular syndrome with myolysis during long-term treatment with fibrates].
Acute inflammatory muscular syndromes secondary to clofibrate therapy are rare. They usually present with muscular pain in all four limbs with biochemical signs of rhabdomyolysis. The outcome is favourable as a rule with rapid regression of the clinical and biochemical changes after stopping the responsible drug. The authors report an atypical case of this syndrome with chest pains suggestive of angina.
D002994:Clofibrate / Q000009:adverse effects*; D003402:Creatine Kinase / Q000097:blood; D005634:Fructose-Bisphosphate Aldolase / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000139:chemically induced* / Q000201:enzymology; D010146:Pain; D012206:Rhabdomyolysis / Q000139:chemically induced; D013577:Syndrome; D013997:Time Factors
D003402:Creatine Kinase; D005634:Fructose-Bisphosphate Aldolase; D002994:Clofibrate
Syndrome musculaire atypique avec myolyse au cours d'un traitement chronique par fibrates.