title: Maternal and neonatal responses to alfentanil administered before induction of general anaesthesia for caesarean section.
abstract: The cardiovascular response to tracheal intubation was compared in two groups of patients undergoing elective Caesarean section. Both groups received a standard technique of general anaesthesia. One of the groups received alfentanil 10 micrograms kg-1 1 min before induction of anaesthesia, the other acted as a control group. In the alfentanil group there was a significant modification of the cardiovascular response to intubation as compared with the control group (P less than 0.01). No adverse effect on the neonate was seen. However, a significant increase in the incidence of postoperative nausea occurred in mothers in the alfentanil group (P less than 0.05).
mesh_terms: D000759:Adjuvants, Anesthesia / Q000494:pharmacology*; D015760:Alfentanil; D000768:Anesthesia, General / Q000009:adverse effects; D000773:Anesthesia, Obstetrical / Q000009:adverse effects; D001034:Apgar Score; D002585:Cesarean Section; D005260:Female; D005283:Fentanyl / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000494:pharmacology; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D007442:Intubation, Intratracheal; D011247:Pregnancy
chemical_list: D000759:Adjuvants, Anesthesia; D015760:Alfentanil; D005283:Fentanyl