Multifocal renal cell carcinoma: a cytogenetic study.
A case of multifocal renal cell carcinoma (RCC) is reported. A detailed cytogenetic study revealed diverse clonal chromosomal aberrations in both tumours and demonstrated the multiple origin of these tumours. The tool of chromosome analysis in discriminating between multifocal renal cell tumours and local metastasis, as well as in the determination of renal adenomas and carcinomas is discussed.
D000368:Aged; D002292:Carcinoma, Renal Cell / Q000235:genetics* / Q000473:pathology; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D005260:Female; D006801:Humans; D007621:Karyotyping; D007668:Kidney / Q000473:pathology; D007680:Kidney Neoplasms / Q000235:genetics* / Q000473:pathology; D008677:Metaphase; D009378:Neoplasms, Multiple Primary / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic; D014407:Tumor Cells, Cultured