Multiple myeloma: a study of 10 cases.
The clinical, radiographical, biochemical, microscopical and ultrastructural features of 10 cases of multiple myeloma were studied. The skull and jaw regions were frequently involved by the disease and although the diagnosis remains multidisciplinary, microscopical parameters differentiating a myelomatous bone marrow infiltrate from a reactive plasmacytosis are discussed. Biochemical and microscopical factors influencing the prognosis are highlighted and significant ultrastructural findings include erythrophagocytosis, cytoplasmic nuclear asynchrony of plasmablasts and intranuclear viral like inclusions.
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000276:immunology / Q000648:ultrastructure*; D009101:Multiple Myeloma / Q000276:immunology / Q000648:ultrastructure*; D010950:Plasma Cells / Q000276:immunology / Q000648:ultrastructure; D012888:Skull Neoplasms / Q000276:immunology / Q000648:ultrastructure*
D007136:Immunoglobulins