[Effect of antibodies against mitochondrial K+-transporting protein on K+ transport in rat liver mitochondria].
The K+ transport in rat liver mitochondria was studied by the immunochemical method. Antibodies to mitochondrial K+-transporting protein with molecular weight 60 kDa were obtained and used as possible inhibitor or K+ transport. Antibodies depressed the DNP-induced K+ efflux and energy-dependent swelling by 50% without causing changes in respiration and oxidative phosphorylation.
D000818:Animals; D000906:Antibodies / Q000276:immunology*; D001667:Binding, Competitive; D001692:Biological Transport; D002352:Carrier Proteins / Q000276:immunology* / Q000378:metabolism; D005779:Immunodiffusion; D007074:Immunoglobulin G / Q000276:immunology; D008930:Mitochondria, Liver / Q000378:metabolism*; D008933:Mitochondrial Swelling; D011188:Potassium / Q000378:metabolism*; D027961:Potassium-Hydrogen Antiporters; D051381:Rats
D000906:Antibodies; D002352:Carrier Proteins; D007074:Immunoglobulin G; D027961:Potassium-Hydrogen Antiporters; D011188:Potassium
Vliianie antitel k mitokhondrial'nomu K+-transportiruiushchemu belku na transport K+ v mitokhondriiakh pecheni krysy.