title: Effect of multislice interference on image contrast in T2- and T1-weighted MR images.
abstract: Multislice imaging markedly degrades the contrast of T2-weighted MR images as the separation between slices is reduced. Image contrast was measured clinically at 1.5 T and experimentally at 0.15 T as a function of interslice gap width and shown to be in agreement with calculations based on known relaxation times and excitation profiles. Thus, the cause of T2 contrast degradation in multislice sequences is demonstrated. Contrast in T1-weighted sequences is shown to be minimally affected or even slightly enhanced. Selective excitation pulses with better spatial definition will diminish these contrast changes. Since perfect slice profiles can never be achieved, the clinical implications of these findings are discussed for MR imaging. The choice of slice gaps is an important operator-selected parameter in reducing contrast degradation in T2-weighted sequences.
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008953:Models, Anatomic