[Case-controlled study of the prognosis of cardiac insufficiency in treated hypertensive patients].
The aim of this study is to compare the long-term mortality of hypertensive subjects (HT) hospitalized with early heart failure (HF), and HT control without HF. The study is based on a population of 2,050 HT consecutively hospitalized for the first time for high blood pressure, between oct. 1969 and nov. 1983. Among them, 115 presented with early HF (symptoms for less than 3 months, the diagnosis being made mainly on interview data, physical exam, and radio); they were matched with Controls (C) belonging to the same hypertensive population, on the following criteria: same sex, same age (+/- 3 years), same date of entry (+/- 3 months), no HF at entry, 94 Cases (CHF) could be matched: 64 men and 30 women (mean age: 50 +/- 11). A mortality survey was done in April 1985, with response rates of 96 p. 100 (CHF) and 98 p. 100 (C). The mean follow-up period was 11 years. At entry, CHF differed highly significantly form C in many ways, and mainly in higher systolic BP, more frequent ECG changes (LV voltage, J-ST-T changes), more severe fundus oculi changes. The survival rate was assessed by life-table method. As a whole, it was significantly reduced in CHF vs C (p/0.005); the 10-years survival rates were respectively 51% (CHF) and 71% (C). Case-control comparison was examined for both sexes, and after division by the median age (50 years): CHF survival was significantly reduced in women, and in subjects aged 50 and more (p/0.03); no significant difference was observed for men and before 50. CHF were dichotomized for each available item at entry, and lifetable comparison was compared in both issuing sub-groups; no significant difference was observed, but for the age, with a better survival in youngest subjects (p/0.01).(ABSTRACT TRUNCATED AT 250 WORDS)
D000206:Actuarial Analysis; D005260:Female; D006333:Heart Failure / Q000209:etiology / Q000401:mortality*; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy / Q000401:mortality*; D008297:Male; D011379:Prognosis
Etude cas-contrôle du pronostic de l'insuffisance cardiaque chez l'hypertendu traité.