[Comparative expression of 2 intermediate filament proteins, peripherin and the 68 kDa neurofilament protein, during embryonal development of the rat].
Peripherin, an intermediate filament protein, was originally detected by biochemical methods in the neurons of the peripheral nervous system. We now studied its expression and cellular localization by immunocytochemical methods in the developing rat embryo, and compared them with the expression and localization of the 68 kDa neurofilament protein. It appears that peripherin is expressed not only in the neurons of the peripheral nervous system, but also in some well defined neuronal populations of the central nervous system. These results focus on the questions of the phylogenetic origin and of the function of peripherin.
D000818:Animals; D005314:Embryonic and Fetal Development; D005260:Female; D007150:Immunohistochemistry; D007381:Intermediate Filament Proteins / Q000096:biosynthesis*; D008562:Membrane Glycoproteins; D008970:Molecular Weight; D009419:Nerve Tissue Proteins; D016900:Neurofilament Proteins; D064531:Peripherins; D011247:Pregnancy; D051381:Rats
D007381:Intermediate Filament Proteins; D008562:Membrane Glycoproteins; D009419:Nerve Tissue Proteins; D016900:Neurofilament Proteins; D064531:Peripherins
Expression comparée de deux protéines de filaments intermédiaires, la périphérine et la protéine de neurofilament 68 kDa, au cours du développement embryonnaire du rat.