The effects of NH3 and CO2 on the sensory ending of mammalian muscle spindles: intracellular pH as a possible mechanism.
The changes in impulse activity of the sensory endings of single isolated cat muscle spindles, as affected by NH3 and CO2 were analyzed. These changes are most likely caused by corresponding changes in intracellular pH of the sensory endings.
D000200:Action Potentials / Q000187:drug effects; D000641:Ammonia / Q000494:pharmacology*; D000818:Animals; D002245:Carbon Dioxide / Q000494:pharmacology*; D002415:Cats; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D009132:Muscles / Q000187:drug effects / Q000294:innervation* / Q000502:physiology; D009475:Neurons, Afferent / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*
D002245:Carbon Dioxide; D000641:Ammonia