Lower genital tract infections in women: comparison of clinical and epidemiologic findings with microbiology.
We screened 392 women attending the Laboratory of Microbiology of Toulouse Purpan Hospital for symptoms of lower genital tract infection for six microorganisms. Rates of isolation of Neisseria gonorrhoeae, Chlamydia trachomatis, Candida albicans, Mycoplasma hominis, and Gardnerella vaginalis were 1%, 7.7%, 29.8%, 23.8%, and 37.5%, respectively. Trichomonas vaginalis was detected by direct examination in specimens from 3.1% of patients. Another goal of this study was to determine the relative prevalence of these microorganisms in relation to clinical and epidemiologic findings. C. trachomatis was isolated significantly more often from patients under 25 year old (P less than 0.001), from those who use oral contraceptives (P less than 0.01), from those who have a male sexual partner with symptoms of sexually transmitted disease (P less than 0.001), and from those who present signs of cervicitis (P less than 0.05). Isolation of C. albicans was significantly associated with vulvar pruritus (P less than 0.01), vulvitis (P less than 0.01), and vaginitis (P less than 0.001). G. vaginalis and M. hominis are significantly associated with bacterial vaginosis (P less than 0.001). This syndrome was diagnosed clinically in 27.2% of our study population and was highly correlated with use of an intrauterine device (P less than 0.05).
D000818:Animals; D002176:Candida albicans / Q000302:isolation & purification; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D002986:Clinical Trials as Topic; D005260:Female; D005602:France; D006194:Gardnerella vaginalis / Q000302:isolation & purification; D005831:Genital Diseases, Female / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D009174:Mycoplasma / Q000302:isolation & purification; D009344:Neisseria gonorrhoeae / Q000302:isolation & purification; D012749:Sexually Transmitted Diseases / Q000175:diagnosis / Q000382:microbiology; D014246:Trichomonas vaginalis / Q000302:isolation & purification; D014621:Vagina / Q000382:microbiology