[Hypereosinophilia syndrome with cutaneous manifestations, "burning hand" syndrome and increased immunoglobulin levels. Treatment with a combination of DADPS and disodium cromoglycate].
We report on a 78-year-old women suffering from hypereosinophilic syndrome (HES). Aside from pruriginous papules and infiltrations, she showed sensorial polyneuropathy as well as increased levels of immunoglobulins. Treatment with glucocorticoids and azathioprine resulted in good but not complete remission. Total remission was not achieved until after a new combined therapy with DADPS and disodium cromoglycate. We give a survey on the therapeutic range concerning HES.
D000368:Aged; D004205:Cromolyn Sodium / Q000627:therapeutic use*; D003622:Dapsone / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004802:Eosinophilia / Q000188:drug therapy*; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000188:drug therapy*; D012871:Skin Diseases / Q000188:drug therapy*; D013577:Syndrome
D003622:Dapsone; D004205:Cromolyn Sodium
Hypereosinophiliesyndrom mit kutanen Manifestationen, "Burning-Hand"-Syndrom und Immunglobulinerhöhungen. Behandlung mit einer Kombination von DADPS mit Dinatriumcromoglykat.