title: [Nuclear medicine assessment of renal function in beagles before and after extracorporeal percutaneous lithotripsy with a piezoelectric instrument system].
abstract: High energy sound pulses which are generated piezoelectrically can be used for extracorporal lithotripsy as an alternative to shock-waves. Since several years a lithotripter for renal concrements based on piezoelectrical oscillators has been developed at the Department for Urology in Homburg/Saar; W.Germany. The present paper describes animal experiments which have been carried out with Beagle-dogs in order to prove that the sound pulses used for lithotripsy do not affect renal function. This function is measured by methods of nuclear medicine (131J-Hippuran Clearance with a modified evaluation). In addition it is evaluated by 111In labelled leucocytes if inflammatory processes in the kidney are suspected. It could be demonstrated that no detremental effects on the kidneys can be detected even with the most sensitive methods of nuclear medicine.
mesh_terms: D000818:Animals; D004285:Dogs; D005919:Glomerular Filtration Rate; D007205:Indium Radioisotopes; D007465:Iodohippuric Acid; D007669:Kidney Calculi / Q000628:therapy*; D007677:Kidney Function Tests; D008096:Lithotripsy / Q000295:instrumentation*; D009942:Organometallic Compounds; D015125:Oxyquinoline / Q000031:analogs & derivatives
chemical_list: D007205:Indium Radioisotopes; D009942:Organometallic Compounds; C032950:indium oxine; D007465:Iodohippuric Acid; D015125:Oxyquinoline
vernacular_title: Nuklearmedizinische Nierenfunktionsprüfung an Beagle-Hunden vor und nach extrakorporaler perkutaner Lithotripsie mit einem piezoelektrischen Gerätesystem (EPL).