title: Non-mutagenicity of fenvalerate in Drosophila.
abstract: The induction of genetic damage in germ cells of Drosophila melanogaster by the pyrethroid insecticide fenvalerate was studied. Adult feeding, larval feeding and adult injection were the routes of administration used. Our results indicate that, under the conditions of testing, fenvalerate is unable to induce sex-linked recessive lethals, sex-chromosome losses and non-disjunction.
mesh_terms: D000818:Animals; D004331:Drosophila melanogaster / Q000187:drug effects; D005804:Genes, Lethal / Q000187:drug effects; D005808:Genes, Recessive / Q000187:drug effects; D008297:Male; D009152:Mutagenicity Tests / Q000379:methods; D009153:Mutagens; D009570:Nitriles; D009630:Nondisjunction, Genetic; D011722:Pyrethrins / Q000633:toxicity*; D012303:Ring Chromosomes; D012730:Sex Chromosomes / Q000187:drug effects
chemical_list: D009153:Mutagens; D009570:Nitriles; D011722:Pyrethrins; C017690:fenvalerate