Effect of Intralipid infusion on transcutaneous oxygen and carbon dioxide tension in sick neonates.
We evaluated the change in transcutaneous oxygen (tcPo2) and carbon dioxide (tcPco2) tension in response to 60 minutes' infusion of Intralipid (Kabi Vitrum (Saphar] (mean dose (0.16 +/- 0.07 g/kg/h) in neonates with lung disease (hyaline membrane disease or bronchopulmonary dysplasia). The tcPo2 was 10% lower following Intralipid infusion (P less than 0.05), whereas no significant change occurred in tcPco2 measurements. The data confirm the need for limited use of Intralipid in this category of patients.
D001785:Blood Gas Monitoring, Transcutaneous; D001997:Bronchopulmonary Dysplasia / Q000378:metabolism*; D002245:Carbon Dioxide / Q000032:analysis*; D005217:Fat Emulsions, Intravenous / Q000009:adverse effects*; D006801:Humans; D006819:Hyaline Membrane Disease / Q000378:metabolism*; D007231:Infant, Newborn; D010100:Oxygen / Q000032:analysis*; D010313:Partial Pressure; D013997:Time Factors
D005217:Fat Emulsions, Intravenous; D002245:Carbon Dioxide; D010100:Oxygen