The tyrosinase-positive oculocutaneous albinism locus is not linked to the beta-globin locus in man.
Twenty informative families have been studied. and linkage between the tyrosinase-positive oculocutaneous albinism locus and the beta-globin locus has been excluded with a maximum lod score of -9.85 at 0 = 0.05. In lower mammals there is linkage between the p locus (considered to be equivalent to the human tyrosinase-positive oculocutaneous albinism) and the beta-globin locus.
D000417:Albinism / Q000201:enzymology / Q000235:genetics*; D004156:Catechol Oxidase / Q000235:genetics*; D005260:Female; D008040:Genetic Linkage; D005914:Globins / Q000235:genetics*; D006801:Humans; D008297:Male; D014442:Monophenol Monooxygenase / Q000235:genetics*
D005914:Globins; D004156:Catechol Oxidase; D014442:Monophenol Monooxygenase