Lupus anticoagulant and false positive serological tests for syphilis.
A 41-year old male who presented for blood donation for the first time was rejected on the grounds of a positive reaginic serological test (VDRL and RPR) and a specific antitrepomena test (FTA) for syphilis. Later studies revealed the existence of a lupus anticoagulant and this was made responsible for the positive serology. Our observation suggests the need to search for the existence of a lupus anticoagulant in blood donors with non-specific or specific positive antitrepenema test.
D000328:Adult; D001779:Blood Coagulation Factors / Q000032:analysis / Q000276:immunology*; D001782:Blood Donors; D005189:False Positive Reactions; D006801:Humans; D016682:Lupus Coagulation Inhibitor; D008297:Male; D013588:Syphilis Serodiagnosis / Q000379:methods
D001779:Blood Coagulation Factors; D016682:Lupus Coagulation Inhibitor