The 99m technetium labeling effect on bacterial surface properties.
The present study was undertaken to determine whether labeling Pseudomonas aeruginosa with 99m Technetium would modify some of the bacterial physicochemical surface properties which play an important role in the interaction between bacteria and eukaryotic cells. No significant difference in electrophoretic mobility or distribution of cationized ferritin on the cell surface was observed between labeled and unlabeled bacteria. Also, the 99m Tc labeling process did not modify bacterial hydrophobicity or adhesiveness to human buccal epithelial cells. It is concluded that bacterial labeling with 99m Tc can be accepted as a useful method for biological research.
D001422:Bacterial Adhesion; D002462:Cell Membrane / Q000648:ultrastructure; D011550:Pseudomonas aeruginosa / Q000528:radiation effects* / Q000648:ultrastructure; D013667:Technetium
D013667:Technetium