[Treatment of labile forms of diabetes mellitus by transplantation of cultured pancreatic islet cells].
The authors presented data on the transplantation of human fetal and pig pancreatic islet cell cultures to 89 patients with type I diabetes mellitus of a labile course. Allo- and xeno-transplantations of pancreatic islet cell cultures in combination with exogenous insulin administration were shown to improve the patients' general status raising their working capacity. As a result of 118 islet cell transplantations hypoglycemic comas either stopped or became milder and were better corrected. Stabilization of metabolic processes was observed in the patients. Clinicobiochemical indices and subjective signs of diabetes stabilization were observed within 12-15 months after transplantation.
D000293:Adolescent; D000328:Adult; D000818:Animals; D003922:Diabetes Mellitus, Type 1 / Q000601:surgery*; D003924:Diabetes Mellitus, Type 2 / Q000601:surgery*; D005260:Female; D005333:Fetus; D006801:Humans; D016381:Islets of Langerhans Transplantation; D008297:Male; D008875:Middle Aged; D013552:Swine; D014183:Transplantation, Heterologous
Lechenie labil'nykh form sakharnogo diabeta transplantatsieĭ kul'tur ostrovkovykh kletok podzheludochnoĭ zhelezy.