A pneumococcal surface protein (PspB) that exhibits the same protease sensitivity as streptococcal R antigen.
A monoclonal antibody against Streptococcus pneumoniae, designated T4A49, detected a 64,000-molecular-weight protein that was immunologically unrelated to the previously described surface protein PspA. This new protein, designated PspB, was pepsin sensitive and trypsin resistant, as is the R antigen of type 28 group A streptococci.
D000907:Antibodies, Bacterial / Q000276:immunology; D000911:Antibodies, Monoclonal / Q000276:immunology; D000942:Antigens, Bacterial / Q000378:metabolism*; D000954:Antigens, Surface / Q000378:metabolism*; D001426:Bacterial Proteins / Q000276:immunology / Q000378:metabolism*; D015153:Blotting, Western; D008970:Molecular Weight; D010434:Pepsin A / Q000378:metabolism; D013045:Species Specificity; D013296:Streptococcus pneumoniae / Q000276:immunology* / Q000378:metabolism; D014357:Trypsin / Q000378:metabolism
D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial; D000954:Antigens, Surface; D001426:Bacterial Proteins; D014357:Trypsin; D010434:Pepsin A