Intravenous immunoglobulin treatment of pregnant patients with recurrent pregnancy loss caused by antiphospholipid antibodies and Rh immunization.
A patient with antiphospholipid antibodies and nine consecutive fetal deaths and a severely Rh-immunized woman with one previous live birth and seven fetal/neonatal deaths achieved live births after antepartum administration of intravenous immunoglobulin. This agent shows promise as a new treatment for patients with previous repetitive fetal deaths from immunologic causes.
D000328:Adult; D000906:Antibodies / Q000502:physiology*; D005260:Female; D005313:Fetal Death / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D007116:Immunization, Passive; D007275:Injections, Intravenous; D010743:Phospholipids / Q000276:immunology*; D011247:Pregnancy; D012203:Rh Isoimmunization / Q000150:complications*
D000906:Antibodies; D010743:Phospholipids