Actinic reticuloid simulating Sézary syndrome. Report of two cases.
A report is given on two male patients who showed all the main characteristics of Sézary syndrome (SS). When phototested, however, they proved to be extremely photosensitive, which suggested a diagnosis of actinic reticuloid (AR). This was supported by the predominance in blood and skin specimens of lymphoid cells with a suppressor/cytotoxic phenotype, the absence of clonal cell proliferation and a benign clinical course. Differential diagnostic problems of SS and erythrodermic AR are discussed.
Toonstra
J
J
van Weelden
H
H
Gmelig Meyling
F H
FH
van der Putte
S C
SC
Schiere
S I
SI
Baart de la Faille
H
H
D000368:Aged; D001706:Biopsy; D003873:Dermatitis, Exfoliative / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D007958:Leukocyte Count; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010787:Photosensitivity Disorders / Q000473:pathology*; D012751:Sezary Syndrome / Q000473:pathology*; D012867:Skin / Q000473:pathology