[Therapy of alopecia areata with diphenylcyclopropenone].
Induction and maintenance of contact dermatitis of the scalp has proved effective in producing regrowth of hair in patients with alopecia areata. We observed regrowth of hair in 17 out of 20 patients after local application of the contact allergen, diphenylcyclopropenone. Only 3 patients were treated without success. In 3 patients regrowth of hair was also seen in areas that were not treated with diphenylcyclopropenone, suggesting that this treatment has an additional systemic effect. Patient acceptance of the induced dermatitis was excellent.
Kietzmann
H
H
Hardung
H
H
Christophers
E
E
D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000506:Alopecia Areata / Q000188:drug therapy*; D055598:Chemical Phenomena; D002621:Chemistry; D003521:Cyclopropanes / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D003877:Dermatitis, Contact / Q000209:etiology; D003875:Drug Eruptions / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D003521:Cyclopropanes; C029402:diphenylcyclopropenone
Therapie der Alopecia areata mit diphenylcyclopropenon.