Epidermolysis bullosa simplex with keratoderma of the palms and soles.
A family is described who had epidermolysis bullosa (EB) simplex (Koebner) associated with keratoderma of the palms and soles. This association has been infrequently reported in the literature. The keratoderma appears to have a protective effect as these patients developed few palmar and plantar blisters in the area of the keratoderma. EB simplex (Koebner) with keratoderma appears to be a distinct syndrome, but the simultaneous occurrence of two dominantly inherited traits cannot be excluded.
Haber
R M
RM
Ramsay
C A
CA
Boxall
L B
LB
D000293:Adolescent; D000328:Adult; D002648:Child; D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D004820:Epidermolysis Bullosa / Q000150:complications* / Q000235:genetics; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000150:complications* / Q000235:genetics; D008297:Male