title: Depolarization-evoked release of N-acetyl-L-aspartyl-L-glutamate from rat brain synaptosomes.
abstract: Depolarization by potassium and veratridine stimulated the release of N-acetyl-L-aspartyl-L-glutamate from crude synaptosomes prepared from the rat mesencephalon and diencephalon. The potassium-evoked release of N-acetyl-L-aspartyl-L-glutamate was calcium-dependent and the stimulatory effect of veratridine was prevented by tetrodotoxin.
authors.affiliation: Collège de France, INSERM U 114, Chaire de Neuropharmacologie, Paris.
authors.forename: A
authors.initials: A
authors.lastname: Pittaluga
authors.forename: L
authors.initials: L
authors.lastname: Barbeito
authors.forename: V
authors.initials: V
authors.lastname: Serval
authors.forename: G
authors.initials: G
authors.lastname: Godeheu
authors.forename: F
authors.initials: F
authors.lastname: Artaud
authors.forename: J
authors.initials: J
authors.lastname: Glowinski
authors.forename: A
authors.initials: A
authors.lastname: Chéramy
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism*; D000001:Calcimycin / Q000494:pharmacology; D002118:Calcium / Q000494:pharmacology; D004027:Diencephalon / Q000378:metabolism; D004151:Dipeptides / Q000378:metabolism*; D008297:Male; D008636:Mesencephalon / Q000378:metabolism; D011188:Potassium / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D013574:Synaptosomes / Q000378:metabolism*; D013779:Tetrodotoxin / Q000494:pharmacology; D014701:Veratridine / Q000494:pharmacology
chemical_list: D004151:Dipeptides; C027172:isospaglumic acid; D000001:Calcimycin; D013779:Tetrodotoxin; D014701:Veratridine; D011188:Potassium; D002118:Calcium