Delayed seroconversion to HIV in a hemophiliac.
In a 14-year-old boy with severe hemophilia B, HIV seroconversion was observed about 2 years after substitution therapy had been changed to heat-treated PPSB concentrates. This shows that HIV-antibodies may appear in hemophiliacs after time periods longer than generally assumed.
von Hintzenstern
J
J
Klinische und Molekulare Virologie, Universität Erlangen-Nürnberg.
Jahn
G
G
Mang
K
K
Harms
D
D
Fleckenstein
B
B
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology*; D000293:Adolescent; D000914:Antibodies, Viral / Q000032:analysis*; D005164:Factor IX / Q000627:therapeutic use; D006678:HIV / Q000276:immunology*; D015483:HIV Antibodies; D002836:Hemophilia B / Q000276:immunology* / Q000628:therapy; D006801:Humans; D008297:Male
D000914:Antibodies, Viral; D015483:HIV Antibodies; D005164:Factor IX