Hypoxanthine and inosine analogues as chemotherapeutic agents in Chagas' disease.
Analogues of purines, especially those of hypoxanthine and inosine, appear to hold considerable promise for the treatment of Chagas' disease.
Marr
J J
JJ
Department of Medicine, University of Colorado Health Sciences Center, Denver 80262.
Berens
R L
RL
D000818:Animals; D014355:Chagas Disease / Q000188:drug therapy*; D006801:Humans; D007288:Inosine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D011720:Pyrazoles / Q000627:therapeutic use*; D011743:Pyrimidines / Q000627:therapeutic use*; D014344:Trypanocidal Agents / Q000627:therapeutic use*
D011720:Pyrazoles; D011743:Pyrimidines; D014344:Trypanocidal Agents; D007288:Inosine; C048839:9-deazainosine