title: Ocular findings and skin histology in a group of patients with X-linked ichthyosis.
abstract: We carried out ophthalmological examinations, and histopathological examinations of skin biopsies in 32 male patients affected by X-linked ichthyosis. We found corneal opacities in only five patients, and their presence was not related to the age of the patients. Skin histology revealed a reduction of the granular layer in nine cases, a finding previously thought to be typical of autosomal dominant ichthyosis vulgaris.
authors.affiliation: Department of Dermatology, 2nd Faculty of Medicine, University of Naples, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Piccirillo
authors.forename: L
authors.initials: L
authors.lastname: Auricchio
authors.forename: G
authors.initials: G
authors.lastname: Fabbrocini
authors.forename: G
authors.initials: G
authors.lastname: Parenti
authors.forename: A
authors.initials: A
authors.lastname: Ballabio
authors.forename: M
authors.initials: M
authors.lastname: Delfino
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003318:Corneal Opacity / Q000473:pathology*; D008040:Genetic Linkage; D006801:Humans; D007057:Ichthyosis / Q000235:genetics* / Q000473:pathology; D008297:Male; D012867:Skin / Q000473:pathology*; D014960:X Chromosome