BASIC programs to compute source densities from autoradiographic cross-fire matrices.
Two different mathematical procedures to compute source densities from cross-fire matrices in quantitative EM autoradiography are reported. BASIC programs for a desk-top microcomputer were written to fit the hypothetical silver grain distribution to the observed real silver grain distribution using a non-iterative linear process (least-squares procedure) and an iterative method, which minimizes the chi-square component between the observed and computed silver grain distributions. The latter procedure uses a Gauss-Newton algorithm.
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Laboratoires de Biologie Cellulaire-Histologie et de Biochimie, INSERM U 172 CNRS UA 1179, Faculté de Médecine-Nord, Marseille, France.
D001345:Autoradiography / Q000379:methods*; D008432:Mathematical Computing; D008838:Microcomputers; D008854:Microscopy, Electron; D011381:Programming Languages