Chronic berylliosis. Demonstration by gallium-67 imaging and magnetic resonance imaging.
Ga-67 is known to localize in the lungs in a wide spectrum of pulmonary pathology. The nonspecific affinity of Ga-67 uptake in both inflammatory and neoplastic entities limits its utility in terms of pulmonary disease differential diagnosis. However, Ga-67 lung imaging has proven to be helpful in evaluating the extent of inflammatory activity, as well as in assessing responses to therapy. A case of active chronic berylliosis, a disorder in which Ga-67 uptake has not been previously reported is presented. There is diffuse bilateral Ga-67 pulmonary activity before therapy. Subsequent to steroid therapy, a marked decrease in pulmonary gallium uptake activity was noted with only residual hilar and mediastinal adenopathy noted.
Deseran
M W
MW
Department of Radiology, Los Angeles County, University of Southern California Medical Center 90033.
Colletti
P M
PM
Ratto
D
D
Ansari
A N
AN
Siegel
M E
ME
D000328:Adult; D001607:Berylliosis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D002908:Chronic Disease; D005710:Gallium Radioisotopes; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008279:Magnetic Resonance Imaging; D008297:Male; D011877:Radionuclide Imaging
D005710:Gallium Radioisotopes