Systemic sclerosis and digital gangrene without scleroderma.
We report a case of a 67-year-old man with digital gangrene and no other cutaneous evidence of scleroderma. The presence of anticentromere antibody, scleroderma pattern capillary abnormalities, and the histology of the digital artery all supported a diagnosis of systemic sclerosis. Newer diagnostic tools may identify patients who do not fit easily into the current classification of that disease.
Barr
W G
WG
Department of Medicine, Loyola University Stritch School of Medicine, Maywood, IL.
Robinson
J A
JA
D000368:Aged; D000906:Antibodies / Q000032:analysis; D001158:Arteries / Q000473:pathology; D002196:Capillaries / Q000473:pathology; D002503:Centromere / Q000276:immunology; D005385:Fingers / Q000098:blood supply / Q000473:pathology*; D005734:Gangrene; D006801:Humans; D008297:Male; D009262:Nails / Q000098:blood supply; D012595:Scleroderma, Systemic / Q000150:complications* / Q000276:immunology
D000906:Antibodies