Myocardial infarction, persistent coronary artery thrombosis and lupus anticoagulant.
A 40-year-old man who presented with exertional angina had had two myocardial infarctions within the same myocardial distribution several years earlier. Coronary arteriography revealed a large intramural thrombus in the right coronary artery and minimal atherosclerotic disease. Special coagulation studies detected a circulating lupus anticoagulant. The association of repeated episodes of thrombosis and lupus anticoagulant is important. In patients with repeated thrombotic events, the lupus anticoagulant should be sought, particularly in those less than 40 years of age.
Mills
T J
TJ
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota.
Safford
R E
RE
Kazmier
F J
FJ
D000328:Adult; D001779:Blood Coagulation Factors / Q000097:blood / Q000276:immunology*; D001780:Blood Coagulation Tests; D017023:Coronary Angiography; D003327:Coronary Disease / Q000097:blood*; D003328:Coronary Thrombosis / Q000097:blood*; D005080:Exercise Test; D006439:Hemodynamics; D006801:Humans; D016682:Lupus Coagulation Inhibitor; D008297:Male; D009203:Myocardial Infarction / Q000097:blood*
D001779:Blood Coagulation Factors; D016682:Lupus Coagulation Inhibitor