title: Adrenal function in 15 dogs with insulin-dependent diabetes mellitus.
abstract: Pituitary-adrenal function was assessed by a combined dexamethasone suppression-ACTH stimulation test in 15 diabetic and 9 healthy dogs. In both groups, plasma cortisol concentrations decreased (P less than 0.001) after dexamethasone administration and increased (P less than 0.001) after ACTH administration. Differences between groups (P greater than 0.05) and group-by-time interactions were not significant (P greater than 0.05). Seemingly, adrenal function was not altered in well-regulated diabetic dogs.
authors.affiliation: Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing 48824.
authors.forename: C A
authors.initials: CA
authors.lastname: Zerbe
authors.forename: K R
authors.initials: KR
authors.lastname: Refsal
authors.forename: W D
authors.initials: WD
authors.lastname: Schall
authors.forename: R F
authors.initials: RF
authors.lastname: Nachreiner
authors.forename: V V
authors.initials: VV
authors.lastname: Gossain
mesh_terms: D000818:Animals; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000503:physiopathology / Q000662:veterinary*; D004283:Dog Diseases / Q000097:blood / Q000503:physiopathology*; D004285:Dogs; D005260:Female; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D010912:Pituitary-Adrenal Function Tests / Q000662:veterinary; D010913:Pituitary-Adrenal System / Q000503:physiopathology*
chemical_list: D006854:Hydrocortisone