title: [Angiographic evaluation of the response of osteosarcoma to neoadjuvant chemotherapy].
abstract: Modern therapeutic osteosarcoma protocols, including both pre- and post-operative cycles of chemotherapy, have helped improving the quality of the prognosis and marking the local control of the neoplasm more reliable, with a subsequent increase in conservative surgery. Angiographic results of the chemotherapeutic response in 76 patients with primitive high-grade bone osteosarcoma are reported. The need to repeat angiographic controls under the same technical conditions is emphasized. The comparison of the above findings with data from the histological evaluation of the specimen, shows that angiography is a reliable means of evaluating the response to chemotherapy. Angiography is thus emphasized as a valid method in an early evaluation of the efficacy of chemotherapy.
authors.affiliation: Servizio di Radiologia, Istituto Ortopedico Rizzoli, Bologna.
authors.forename: U
authors.initials: U
authors.lastname: Albisinni
authors.forename: S
authors.initials: S
authors.lastname: Galletti
authors.forename: M
authors.initials: M
authors.lastname: Manfrini
authors.forename: G
authors.initials: G
authors.lastname: Pignatti
authors.forename: R
authors.initials: R
authors.lastname: Biagini
authors.forename: P
authors.initials: P
authors.lastname: Picci
authors.forename: G
authors.initials: G
authors.lastname: Bacci
authors.forename: R
authors.initials: R
authors.lastname: Capanna
mesh_terms: D000293:Adolescent; D000792:Angiography; D001859:Bone Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D002945:Cisplatin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use*; D012516:Osteosarcoma / Q000098:blood supply / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology
chemical_list: D002945:Cisplatin; D008727:Methotrexate
vernacular_title: Valutazione angiografica della risposta dell'osteosarcoma alla chemioterapia neoadiuvante.