Topical prostaglandin E2 in the treatment of chronic leg ulcers--a pilot study.
The results of treatment with topical PGE2 dispersed in hydrocolloid granules, in nine patients with chronic leg ulcers is reported. The healing process was evaluated by stereophotogrammetry, which enables objective measurements of ulcer area and volume. Ulcers in eight patients healed completely and that in the ninth, almost completely. These results suggest that topical PGE2 has a beneficial effect in the treatment of leg ulcers.
Eriksson
G
G
Department of Dermatology, Danderyd Hospital, Stockholm, Sweden.
Torngren
M
M
Aly
A
A
Johansson
C
C
D000287:Administration, Topical; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D015232:Dinoprostone; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011458:Prostaglandins E / Q000008:administration & dosage* / Q000627:therapeutic use
D011458:Prostaglandins E; D015232:Dinoprostone