Fourier phase parameters with possible diagnostic importance as obtained from the radionuclide ventriculograms of normal baboons with and without cardiac catheterization and under prolonged anaesthesia.
The possible diagnostic importance of parameters defined from radionuclide ventriculograms and Fourier phase analysis was investigated for data from normal baboons (Papio ursinus) under prolonged anaesthesia (7 hours). Of the 14 animals, 7 were studied using indwelling cardiac catheters. Phase angle differences between the electromechanical activation of the septum and left lateral wall (LLW), and again between the activation of the septum and the apex indicated no significant differences (p greater than 0.05) for the consecutive hourly values for both catheterized and non-catheterized baboons. Consequently, average values and their ranges (mean +/- 1 S.D.) were obtained for these parameters in each group, and they did not differ significantly between the two groups. As could be expected, the activation delays between the septum and LLW, and the septum and apex differed with the latter being significantly longer. The phase angle histogram parameters of atrial peak width, left ventricular plus right ventricular peak width, (LV + RV), LV-to-RV peak separation and LV-to-atrial peak separation were similarly analysed and found not to change significantly between hourly measurements or because of catheterization. Therefore mean normal values and ranges were also obtained for these parameters, possibly to serve as baselines in the diagnosis of subtle conduction pathology.
Hugo
N
N
H.A. Grove Animal Research Centre, Pretoria, Republic of South Africa.
Dormehl
I C
IC
Maree
M
M
Hordijk
C
C
De Winter
R
R
Burow
R
R
D000768:Anesthesia, General; D000818:Animals; D006328:Cardiac Catheterization; D005583:Fourier Analysis; D006321:Heart / Q000000981:diagnostic imaging*; D008297:Male; D009200:Myocardial Contraction; D010215:Papio; D011877:Radionuclide Imaging; D012016:Reference Values; D013667:Technetium; D013997:Time Factors
D013667:Technetium