title: [Gold-induced systemic lupus erythematosus].
abstract: After 10 months of treatment with sodiumaureo-thiomalate a 12 year old girl with severe exsudative polyarthritis developed pericarditis and high titers of antinuclear antibodies as well as antibodies to native double-stranded DNA. At that time the cumulative gold dose was 550 mg. After withdrawal of gold medication the clinical symptoms rapidly disappeared and did not recur after a follow-up period of now 5 years. The titers of autoantibodies decreased to normal levels within a year.
authors.affiliation: Zentrum für Kinderheilkunde, Universität Düsseldorf.
authors.forename: D
authors.initials: D
authors.lastname: Körholz
authors.forename: W
authors.initials: W
authors.lastname: Nürnberger
authors.forename: U
authors.initials: U
authors.lastname: Göbel
authors.forename: V
authors.initials: V
authors.lastname: Wahn
mesh_terms: D000974:Antibodies, Antinuclear / Q000032:analysis*; D001171:Arthritis, Juvenile / Q000188:drug therapy*; D002648:Child; D005260:Female; D006052:Gold Sodium Thiomalate / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced*
chemical_list: D000974:Antibodies, Antinuclear; D006052:Gold Sodium Thiomalate
vernacular_title: Gold-induzierter systemischer Lupus erythematodes.