Primary glomerulonephritis in Hong Kong.
The clinical presentation and natural history of 428 patients with biopsy-proven primary glomerulonephritis were reviewed. Minimal change glomerulonephritis presented with the nephrotic syndrome and followed a benign course. Membranous glomerulonephritis took a slow downhill course. HBs antigenaemia was present in 30% of patients with membranous glomerulonephritis. Mesangiocapillary glomerulonephritis often presented with mixed nephritic-nephrotic syndrome and had a bad prognosis. No type II variant was detected. Mesangial IgA glomerulonephritis commonly presented with abnormal urinary sediments although 2.5% of adults presenting with the nephrotic syndrome without glomerular insufficiency had mesangial IgA disease. Mesangial IgA glomerulonephritis was an important cause of end-stage renal failure in Hong Kong.
Chan
M K
MK
Department of Medicine, University of Hong Kong.
Yin
P D
PD
Chan
K W
KW
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D005921:Glomerulonephritis / Q000473:pathology*; D006723:Hong Kong; D006801:Humans; D008297:Male; D008875:Middle Aged