[Toxic effect of fluid accumulated within silicone regeneration chambers on the survival and proliferation of fibroblasts of the heart of newborn rats].
Liquid collected from silicone impermeable sciatic regeneration chambers, fetal calf serum (FCS) and rat serum at different dilutions were tested on fibroblasts originating from hearts of newborn rats. The lower liquid dilutions presented a toxic effect. This effect was not counteracted by simultaneous addition of FCS at the same dilution. No evidence of a trophic activity was found in the liquid.
Hurtado
H
H
Université catholique de Louvain, Laboratoire de Biologie cellulaire, Louvain-la-Neuve, Belgique.
de Paermentier
F
F
van den Bosch de Aguilar
P
P
D000818:Animals; D000831:Animals, Newborn; D002455:Cell Division; D002470:Cell Survival; D004864:Equipment and Supplies; D005347:Fibroblasts / Q000166:cytology*; D008297:Male; D009206:Myocardium / Q000166:cytology*; D009416:Nerve Regeneration; D051381:Rats; D011919:Rats, Inbred Strains; D012584:Sciatic Nerve; D012828:Silicones
D012828:Silicones
Effet toxique du liquide accumulé dans une chambre de régénération en silicone sur la survie et la prolifération de fibroblastes provenant du coeur de rats nouveau-nés.