title: Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin papillomas and carcinomas by dehydroepiandrosterone and 3-beta-methylandrost-5-en-17-one in mice.
abstract: Topical application of the adrenal steroid, dehydroepiandrosterone, or the synthetic steroid, 3-beta-methylandrost-5-en-17-one, which unlike dehydroepiandrosterone is not demonstrably uterotrophic, inhibits 7,12-dimethylbenz(a)anthracene-induced skin papillomas and carcinomas in the CD-1 mouse.
authors.forename: L L
authors.initials: LL
authors.lastname: Pashko
authors.forename: G C
authors.initials: GC
authors.lastname: Hard
authors.forename: R J
authors.initials: RJ
authors.lastname: Rovito
authors.forename: J R
authors.initials: JR
authors.lastname: Williams
authors.forename: E L
authors.initials: EL
authors.lastname: Sobel
authors.forename: A G
authors.initials: AG
authors.lastname: Schwartz
mesh_terms: D015127:9,10-Dimethyl-1,2-benzanthracene; D000287:Administration, Topical; D000736:Androstenes / Q000008:administration & dosage / Q000627:therapeutic use*; D000818:Animals; D000970:Antineoplastic Agents; D003687:Dehydroepiandrosterone / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D051379:Mice; D010212:Papilloma / Q000139:chemically induced / Q000188:drug therapy*; D012878:Skin Neoplasms / Q000139:chemically induced / Q000188:drug therapy*
chemical_list: D000736:Androstenes; D000970:Antineoplastic Agents; D003687:Dehydroepiandrosterone; D015127:9,10-Dimethyl-1,2-benzanthracene; C040993:3-methylandrost-5-en-17-one