Van der Woude syndrome--recognition of lesser expressions: case report.
A family with Van der Woude syndrome is described. The proband, whose mother and brother had facial clefting, showed inconspicuous abnormalities of the lower lip and a bifid uvula. Lesser expressions of Van der Woude syndrome are common and should be actively looked for in counseling families about cleft lip or cleft lip and palate.
Menko
F H
FH
Institute of Human Genetics, Free University, Amsterdam, The Netherlands.
Koedijk
P H
PH
Baart
J A
JA
Kwee
M L
ML
D000328:Adult; D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D002971:Cleft Lip / Q000235:genetics*; D002972:Cleft Palate / Q000235:genetics; D005260:Female; D005786:Gene Expression Regulation; D005799:Genes, Dominant; D006801:Humans; D008297:Male; D010375:Pedigree; D013577:Syndrome; D014609:Uvula / Q000002:abnormalities