[Prognostic value of the N-myc oncogene in neuroblastoma].
Activation of cellular proto-oncogenes can be detected in several human cancers. In neuroblastoma, amplification and overexpression of N-myc oncogene have been shown to be associated with advanced stages of disease and rapid tumor progression. These results suggest the clinical importance of the N-myc oncogene. Other oncogenes might also be activated in this cancer.
Benard
J
J
Laboratoire de pharmacologie clinique et moléculaire, Institut Gustave-Roussy, Villejuif, France.
D000818:Animals; D005260:Female; D005786:Gene Expression Regulation; D005819:Genetic Markers; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D009447:Neuroblastoma / Q000235:genetics* / Q000473:pathology; D009857:Oncogenes; D011379:Prognosis; D051381:Rats
D005819:Genetic Markers
Intérêt pronostique de l'oncogène N-myc dans les neuroblastomes.