A new chromosomal abnormality in a patient with acute myelomonocytic leukemia.
A new chromosomal abnormality is being presented in a patient with acute myelomonocytic leukemia (AMMoL). The cytogenetic findings in this case can be described as 43, XY, t(12;17) (q12;p13), del (4) (q31), -5,-7. This patient developed a treatment-associated leukemia. The possible causal and clinical implications in such patients with unusual cytogenetic findings are stressed. In addition, basic biological as well as public health implications are discussed which are based on particular cytogenetic abnormalities.
Abramson
J
J
Interfaith Medical Center, Coney Island Hospital, Brooklyn, N.Y.
Verma
R S
RS
Schwartz
J
J
D000368:Aged; D002869:Chromosome Aberrations; D002895:Chromosomes, Human, Pair 5; D002897:Chromosomes, Human, Pair 7; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic