title: Changes in serum lipids in patients with condylomata acuminata treated with interferon alfa-n1 (Wellferon).
abstract: Nine men with refractory condylomata acuminata were treated with intramuscular interferon alfa-n1 and the effect on their serum lipid levels was noted. Comparison of lipid panels before and after interferon revealed that all nine patients had an increase (median 62 mg/dl, p = 0.004) in their triglyceride level and a decrease (median 21 mg/dl, p = 0.004) in high-density lipoprotein cholesterol levels. Total cholesterol levels tended to decrease but the change was not statistically significant. This effect on serum lipids should be considered when interferon alfa-n1 is used in the treatment of genital warts.
authors.affiliation: Duke University Medical Center, Department of Medicine, Durham, NC 27710.
authors.forename: E A
authors.initials: EA
authors.lastname: Olsen
authors.forename: G R
authors.initials: GR
authors.lastname: Lichtenstein
authors.forename: W E
authors.initials: WE
authors.lastname: Wilkinson
mesh_terms: D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D015243:Cholesterol, VLDL / Q000097:blood; D003218:Condylomata Acuminata / Q000628:therapy*; D006801:Humans; D007370:Interferon Type I / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D014280:Triglycerides / Q000097:blood*
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D015243:Cholesterol, VLDL; D007370:Interferon Type I; D014280:Triglycerides; D002784:Cholesterol