Detection of HIV-1 neutralizing antibodies by a simple, rapid, colorimetric assay.
A rapid, simple, reproducible and semi-quantitative assay to measure neutralizing antibodies has been developed. It employs a unique cell line which is exquisitively sensitive to infection with all HIV isolates tested. The assay is amenable to microtiter formulation as well as analysis by automation.
Langlois
A J
AJ
Duke University Medical Center, Department of Surgery, Durham, NC 27710.
Matthews
T J
TJ
Weinhold
K J
KJ
Chaffee
S
S
Hershfield
M
M
Bolognesi
D P
DP
D000914:Antibodies, Viral / Q000032:analysis*; D002460:Cell Line; D003124:Colorimetry; D006678:HIV / Q000276:immunology*; D015483:HIV Antibodies; D006801:Humans; D009500:Neutralization Tests / Q000379:methods*
D000914:Antibodies, Viral; D015483:HIV Antibodies