title: A sonographic sign for the detection in the second trimester of the fetus with Down's syndrome.
abstract: Sonographic structural surveys were made at the time that 904 amniocenteses were performed for genetic evaluation in the second trimester. A sonographic sign was identified which places the fetus at high risk for having Down's syndrome.
authors.forename: B R
authors.initials: BR
authors.lastname: Benacerraf
authors.forename: V A
authors.initials: VA
authors.lastname: Barss
authors.forename: L A
authors.initials: LA
authors.lastname: Laboda
mesh_terms: D000649:Amniocentesis; D004314:Down Syndrome / Q000175:diagnosis*; D005189:False Positive Reactions; D005260:Female; D006257:Head / Q000196:embryology; D006801:Humans; D009333:Neck / Q000196:embryology; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011296:Prenatal Diagnosis / Q000379:methods*; D012306:Risk; D012867:Skin; D014463:Ultrasonography