Ocular findings and skin histology in a group of patients with X-linked ichthyosis.
We carried out ophthalmological examinations, and histopathological examinations of skin biopsies in 32 male patients affected by X-linked ichthyosis. We found corneal opacities in only five patients, and their presence was not related to the age of the patients. Skin histology revealed a reduction of the granular layer in nine cases, a finding previously thought to be typical of autosomal dominant ichthyosis vulgaris.
Piccirillo
A
A
Department of Dermatology, 2nd Faculty of Medicine, University of Naples, Italy.
Auricchio
L
L
Fabbrocini
G
G
Parenti
G
G
Ballabio
A
A
Delfino
M
M
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003318:Corneal Opacity / Q000473:pathology*; D008040:Genetic Linkage; D006801:Humans; D007057:Ichthyosis / Q000235:genetics* / Q000473:pathology; D008297:Male; D012867:Skin / Q000473:pathology*; D014960:X Chromosome