Metabolic and phagocytic activities of the mouse retina after 6-hydroxydopamine treatment.
The activities in mouse retinae were evaluated after 6-hydroxydopamine injection. A significant increase in labeled leucine uptake was evident in the photoreceptor layer. Latex uptake in the pigment epithelium showed no changes. Denervation of catecholaminergic terminals inside the retinae thus affected the metabolism of photoreceptors.
Yew
D T
DT
Department of Anatomy, Chinese University of Hong Kong, Shatin, N.T.
Li
W W
WW
Zhang
D R
DR
Luo
Z B
ZB
D000818:Animals; D002395:Catecholamines / Q000378:metabolism; D004848:Epithelium / Q000187:drug effects / Q000378:metabolism; D006892:Hydroxydopamines / Q000494:pharmacology*; D051379:Mice; D008815:Mice, Inbred Strains; D016627:Oxidopamine; D010587:Phagocytosis / Q000187:drug effects*; D012160:Retina / Q000187:drug effects / Q000276:immunology / Q000378:metabolism*
D002395:Catecholamines; D006892:Hydroxydopamines; D016627:Oxidopamine