title: Poor accumulation of technetium-99m glucoheptonate in sarcoidosis and other diffuse infiltrative lung diseases as compared with gallium-67 citrate.
abstract: Forty-two patients with diffuse infiltrative lung diseases were imaged with Ga-67 citrate and Tc-99m glucoheptonate (GH). Twenty patients had sarcoidosis, six had fibrosis, six had tuberculosis, nine had lung infiltration, and one had pleural empyema. The main difference between Ga-67 and Tc-99m GH was the much greater uptake of Ga-67 in sarcoidosis than that of Tc-99m GH. Fifteen patients with sarcoidosis had positive Ga-67 scans but only six had positive Tc-99m GH scans. The results in other diffuse infiltrative lung diseases were almost equal with Ga-67 and Tc-99m GH. Although Tc-99m GH is less expensive and simpler to use, it is not an adequate substitute for Ga-67 in diffuse infiltrative lung diseases.
authors.affiliation: Department of Nuclear Medicine, Päijät-Häme Central Hospital, Lahti, Finland.
authors.forename: M
authors.initials: M
authors.lastname: Vorne
authors.forename: K
authors.initials: K
authors.lastname: Sahlström
authors.forename: K
authors.initials: K
authors.lastname: Alanko
mesh_terms: D005710:Gallium Radioisotopes; D006801:Humans; D008171:Lung Diseases / Q000000981:diagnostic imaging*; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D012507:Sarcoidosis / Q000000981:diagnostic imaging*; D013400:Sugar Acids; D013667:Technetium
chemical_list: D005710:Gallium Radioisotopes; D015609:Organotechnetium Compounds; D013400:Sugar Acids; D013667:Technetium; C100014:technetium Tc 99m gluceptate