[Changes of peripheral lymphocyte subsets in patients with oral squamous carcinoma].
The distribution of peripheral lymphocyte subsets of 32 patients, who had undergone surgical removal of squamous carcinoma and have evaded recurrence was studied using OK series monoclonal antibodies. The T-lymphocyte subpopulation was reduced in patients who were tumor free for more than 3 years. The helper/inducer T-cell subpopulation was reduced in most of the patients studied, whereas little change was observed in the subpopulation of suppressor/cytotoxic T cells. Consequently the ratio of OKT 4+/OKT 8+ was reduced in accordance with the tumor free period.
Moroyama
T
T
Endo
K
K
Hazutani
J
J
Iwao
I
I
Shiratsuki
T
T
Mitsui
K
K
Sugihara
K
K
Okahara
Y
Y
Hara
J
J
Sakamoto
T
T
D000328:Adult; D000368:Aged; D001402:B-Lymphocytes / Q000276:immunology; D002294:Carcinoma, Squamous Cell / Q000276:immunology*; D005260:Female; D006801:Humans; D007573:Jaw Neoplasms / Q000276:immunology*; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000276:immunology*; D013601:T-Lymphocytes / Q000145:classification*; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology