title: Genetic studies among the sedentes and migrant Oraons of eastern India.
abstract: A total of 334 Oraons of both sexes from two localities in eastern India were tested for 11 polymorphic and six monomorphic blood genetic markers. The sample comprised 130 sedentes from the Gumla district in Bihar and 204 migrants to the Jalpaiguri district of North Bengal. At the hemoglobin locus one example of HbAS was observed in the Gumla sample, while two cases of HbAS were found in the Jalpaiguri group. The Oraons are a distinct tribe and are characterized by a very low frequency of Hp1, TFC2, and a high frequency of TfD1 and GcIF at the serum protein loci. In the red cell enzyme systems the Oraons have a higher frequency of pa at the acid phosphatase locus and GLO1 at the Glyoxalase I locus. Absence of red cell lactate dehydrogenase and very low HbS and GdB- is also characteristic of the Oraons. A probable new nondeficient slow variant of Gd has been observed in polymorphic frequency in the Oraons of Gumla. There was an excess of homozygotes at the Gc locus. No significant difference in the gene frequency between the two groups of Oraons was observed at any of the loci. Genetic distance estimates using the gene frequency data indicate that the Oraons of the two localities are genetically homogeneous and form one cluster with the Bhils. They are nearer to the Irula and Kurumba tribes of the Nilgiris rather than the other Dravidian tribes, Tamils, or Nayars.
authors.affiliation: Department of Biochemistry, National University of Singapore.
authors.forename: N
authors.initials: N
authors.lastname: Saha
authors.forename: J
authors.initials: J
authors.lastname: Tay
authors.forename: C
authors.initials: C
authors.lastname: Piplai
authors.forename: R
authors.initials: R
authors.lastname: Gupta
authors.forename: S K
authors.initials: SK
authors.lastname: Roy
mesh_terms: D001798:Blood Proteins / Q000235:genetics*; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers; D005828:Genetics, Population; D006801:Humans; D007194:India; D008297:Male; D011110:Polymorphism, Genetic
chemical_list: D001798:Blood Proteins; D005819:Genetic Markers