title: Prevalence and clinical peculiarities of essential hypertension in a population living at high altitude.
abstract: Screening examinations were performed in ethnically related populations of men aged 30-59 years, living in high mountain regions of Tien-Shan and Pamir (2800-3600 m above sea level) and in the lowlands (800-900 m). The incidence of borderline hypertension (BH) and essential hypertension (EH) was statistically significantly higher among the inhabitants of lowland regions: EH was recorded among them in 15.4%, vs. 4.2% among men living at high altitude; BH was present among the male lowland population (LL) in 10.6% vs. 6.0% among highlanders (HL). The main characteristic clinico-functional feature of EH in HL was its frequent association with high-altitude pulmonary hypertension and right ventricular hypertrophy. Aldosterone excretion was in HL with EH substantially lower, and sodium excretion higher, than in a comparable group of lowland inhabitants.
authors.forename: M M
authors.initials: MM
authors.lastname: Mirrakhimov
authors.forename: Zh S
authors.initials: ZhS
authors.lastname: Rafibekova
authors.forename: A S
authors.initials: AS
authors.lastname: Dzhumagulova
authors.forename: T S
authors.initials: TS
authors.lastname: Meimanaliev
authors.forename: T M
authors.initials: TM
authors.lastname: Murataliev
authors.forename: K K
authors.initials: KK
authors.lastname: Shatemirova
mesh_terms: D000328:Adult; D000367:Age Factors; D000450:Aldosterone / Q000097:blood; D000472:Alkalosis, Respiratory / Q000209:etiology / Q000378:metabolism; D000531:Altitude; D000532:Altitude Sickness / Q000150:complications / Q000453:epidemiology; D006332:Cardiomegaly / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D006973:Hypertension / Q000453:epidemiology* / Q000378:metabolism; D006976:Hypertension, Pulmonary / Q000453:epidemiology / Q000209:etiology; D007707:Kyrgyzstan; D050356:Lipid Metabolism; D008297:Male; D008875:Middle Aged; D009790:Occupations; D011188:Potassium / Q000032:analysis
chemical_list: D000450:Aldosterone; D011188:Potassium