title: Amino acid sequence of a lysozyme (B-enzyme) from Bacillus subtilis YT-25.
abstract: The amino acid sequence of a lysozyme, (B-enzyme), from Bacillus subtilis YT-25 was determined by conventional methods. B-Enzyme comprised 117 amino acid residues and had a heterogeneous sequence in the amino-terminal region. The amino acid sequence of B-enzyme was different from those of all other lysozymes the sequences of which are known. However, the partial amino acid sequence of Ser(74) to Ser(97) of B-enzyme was homologous with that of the active-site region of hen egg-white lysozyme (Ser(36) to Ser(60], which includes one of the catalytic amino acids, Asp(52). It is interesting that B-enzyme has an amino acid sequence homologous with that of the gag protein p25 of the AIDS virus ARV-2.
authors.affiliation: Department of Chemistry, Osaka University College of Science.
authors.forename: K
authors.initials: K
authors.lastname: Kamei
authors.forename: S
authors.initials: S
authors.lastname: Hara
authors.forename: T
authors.initials: T
authors.lastname: Ikenaka
authors.forename: S
authors.initials: S
authors.lastname: Murao
mesh_terms: D000595:Amino Acid Sequence; D001412:Bacillus subtilis / Q000201:enzymology*; D015683:Gene Products, gag; D006678:HIV / Q000235:genetics; D008247:Lysosomes / Q000032:analysis*; D008969:Molecular Sequence Data; D010449:Peptide Mapping; D012191:Retroviridae Proteins / Q000235:genetics; D012689:Sequence Homology, Nucleic Acid; D014357:Trypsin
chemical_list: D015683:Gene Products, gag; D012191:Retroviridae Proteins; D014357:Trypsin