A comparison of the carbon dioxide and neodymium: YAG lasers in a canine model of acquired subglottic stenosis.
In a previously defined canine model of subglottic stenosis, two different wavelength lasers--the carbon dioxide (CO2) and the neodymium-yttrium aluminum garnet (Nd:YAG)--were used as the principal surgical therapy, and the results were compared. Two lathyrogenic agents, colchicine and penicillamine, were also used in a subset of each treatment group in order to determine their effect as an adjunct to laser therapy in the treatment of subglottic stenosis. The CO2 laser treatment group showed an overall improvement; the Nd:YAG laser treatment group showed a worsening of subglottic stenosis. The dogs treated with the lathyrogenic agents had no added benefit from the use of these agents.
Koufman
J A
JA
Department of Surgery, Bowman Gray School of Medicine, Wake Forest University Medical Center, Winston-Salem, North Carolina 27103.
Branch
M E
ME
Ryu
J H
JH
D000535:Aluminum; D000818:Animals; D002245:Carbon Dioxide; D004195:Disease Models, Animal; D004285:Dogs; D005260:Female; D007829:Laryngostenosis / Q000601:surgery*; D053685:Laser Therapy; D008297:Male; D009354:Neodymium; D015019:Yttrium
D002245:Carbon Dioxide; D009354:Neodymium; D015019:Yttrium; D000535:Aluminum