title: Synaptic action of layer I fibers on cells in cat striate cortex.
abstract: The synaptic action of layer I (LI) and white matter (WM) fibers in cat striate cells was studied intracellularly in slice preparations. LI stimulation produced excitation only in layer II-III and V cells, and inhibition broadly in layer II-VI cells. WM stimulation produced both excitation and inhibition in most cortical cells. Kynurenate, a glutamate antagonist, strongly depressed WM-evoked excitation, but it left LI-evoked excitation considerably unaffected.
authors.affiliation: Department of Psychiatry, Kyoto Prefectural University of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Nakajima
authors.forename: Y
authors.initials: Y
authors.lastname: Komatsu
authors.forename: K
authors.initials: K
authors.lastname: Toyama
mesh_terms: D000818:Animals; D002415:Cats; D004558:Electric Stimulation; D005074:Evoked Potentials, Visual / Q000187:drug effects; D066298:In Vitro Techniques; D007736:Kynurenic Acid / Q000494:pharmacology; D009474:Neurons / Q000145:classification / Q000187:drug effects / Q000502:physiology*; D013569:Synapses / Q000187:drug effects / Q000502:physiology*; D014793:Visual Cortex / Q000187:drug effects / Q000502:physiology*
chemical_list: D007736:Kynurenic Acid