title: [On the problem of the cardiotoxicity of epirubicin-cisplatin].
abstract: Cardiotoxicity is supposed to be the most important limiting factor in chemotherapy with anthracycline derivatives. The left ventricular ejection fraction was measured several times by means of radionuclid - scintigraphy in 24 patients treated with epirubicin - cisplatinum. Pathologic values have been found only in 3 patients, but no correlation with age, cumulative dose or dose/m2 of body surface could be demonstrated.
authors.affiliation: Universitäts-Klinik für Frauenheilkunde, Universitäts-Klinik für Nuklearmedizin, Innsbruck.
authors.forename: W
authors.initials: W
authors.lastname: Lechner
authors.forename: W
authors.initials: W
authors.lastname: Zechmann
authors.forename: P
authors.initials: P
authors.lastname: Mayr
authors.forename: W
authors.initials: W
authors.lastname: Reider
authors.forename: C
authors.initials: C
authors.lastname: Marth
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D002302:Cardiac Output / Q000187:drug effects; D009202:Cardiomyopathies / Q000139:chemically induced*; D002945:Cisplatin / Q000009:adverse effects; D004317:Doxorubicin / Q000009:adverse effects; D015251:Epirubicin; D005260:Female; D006801:Humans
chemical_list: D015251:Epirubicin; D004317:Doxorubicin; D002945:Cisplatin
vernacular_title: Zur Frage der Kardiotoxizität von Epirubicin--Cisplatin.