title: An endogenous ligand for the central sulfonylurea receptor.
abstract: An endogenous ligand for the rat central sulfonylurea receptor has been evidenced in the rat central nervous system. The characteristics of this ligand (extractibility, non-dialysability, chromatographic behaviour on different media, sensitivity to proteases) indicate that it is a neutral to slightly basic peptide.
authors.affiliation: Centre CNRS-INSERM de Pharmacologie-Endocrinologie, Montpellier, France.
authors.forename: A
authors.initials: A
authors.lastname: Virsolvy-Vergine
authors.forename: M
authors.initials: M
authors.lastname: Brück
authors.forename: M
authors.initials: M
authors.lastname: Dufour
authors.forename: A
authors.initials: A
authors.lastname: Cauvin
authors.forename: B
authors.initials: B
authors.lastname: Lupo
authors.forename: D
authors.initials: D
authors.lastname: Bataille
mesh_terms: D018528:ATP-Binding Cassette Transporters; D000818:Animals; D002462:Cell Membrane / Q000032:analysis / Q000378:metabolism; D002540:Cerebral Cortex / Q000032:analysis* / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D002852:Chromatography, Ion Exchange; D005913:Glipizide / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D008297:Male; D008970:Molecular Weight; D010206:Papain / Q000494:pharmacology; D010434:Pepsin A / Q000494:pharmacology; D010455:Peptides / Q000032:analysis* / Q000378:metabolism; D010741:Phospholipases A / Q000494:pharmacology; D015221:Potassium Channels; D024661:Potassium Channels, Inwardly Rectifying; D051381:Rats; D011919:Rats, Inbred Strains; D011955:Receptors, Drug / Q000378:metabolism*; D064233:Sulfonylurea Receptors
chemical_list: D018528:ATP-Binding Cassette Transporters; D010455:Peptides; D015221:Potassium Channels; D024661:Potassium Channels, Inwardly Rectifying; D011955:Receptors, Drug; D064233:Sulfonylurea Receptors; D010741:Phospholipases A; D010206:Papain; D010434:Pepsin A; D005913:Glipizide