3p involvement in a renal cell carcinoma in von Hippel-Lindau syndrome. Region of tumor breakpoint clustering on 3p?
The cytogenetic findings in a renal cell carcinoma from a patient with von Hippel-Lindau syndrome are reported. Of the two consistent changes, one was a dicentric chromosome evolving from an unbalanced translocation between the proximal part of the short arm of chromosome 3 and the distal segment of the long arm of the X chromosome.
Decker
H J
HJ
Cancer Center, Southwest Biomedical Research Institute, Scottsdale, Arizona 85251.
Neumann
H P
HP
Walter
T A
TA
Sandberg
A A
AA
D000328:Adult; D000798:Angiomatosis / Q000235:genetics*; D002292:Carcinoma, Renal Cell / Q000235:genetics*; D002871:Chromosome Banding; D002893:Chromosomes, Human, Pair 3; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D007680:Kidney Neoplasms / Q000235:genetics*; D009378:Neoplasms, Multiple Primary / Q000235:genetics*; D014178:Translocation, Genetic; D006623:von Hippel-Lindau Disease / Q000235:genetics*
D005819:Genetic Markers