[A retrospective study of HBsAG carriers in the blood bank of Navarra].
The following is a review of the data of hepatitis-B serology study obtained during the last sixteen years in the Blood Bank of Navarra. The prevalence of HBsAg carriers is 0.87% (204 positive cases in 23,409 blood donors studied). The methods used during this period have been: AGD (7 positive donors, i.e. 3.4%), CIEP (4 positive donors, i.e. 1.9%), HARP (78 positive donors, i.e. 38.2%), EIA (93 positive donors, i.e. 45.5%) and RIA (22 positive donors, i.e. 10.7%). The number of previous donations before the detection of HBsAg dropped from 7/8 in the first group of donors to 4/5 in the second and to 1 in the third group. A deeper study has been carried out in 120 of those blood donors, including the detection of anti-HBs, anti-HBc, HBeAg and anti-HBe. A low-infectivity pattern has been found in 92 (76.6%), high infectivity in 4 (3.3%) and seroconversion in 16 (13.3%). It hasn't been possible to interpret the pattern of the remaining 8 (6.6%). Both the sensitivity and the specificity of our actual screening method have been found adequate in a cooperative study carried out in a group of Blood Banks in Spain in 1985.
Medarde
A
A
Banco de Sangre, Navarra.
del Hierro
J
J
Aramburu
E
E
Esquíroz
P
P
Martínez
J L
JL
D001771:Blood Banks; D001782:Blood Donors; D002353:Carrier State; D006386:Hemagglutination Tests; D006509:Hepatitis B; D006510:Hepatitis B Antibodies / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006801:Humans; D005779:Immunodiffusion; D007124:Immunoenzyme Techniques; D011863:Radioimmunoassay; D013030:Spain
D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens
Estudio retrospectivo de portadores HBsAg en el Banco de Sangre de Navarra.