Intracardiac thrombosis, phospholipid antibodies, and two-chambered right ventricle.
A 34 year old woman with a history of five spontaneous abortions and a systemic lupus-like illness underwent cardiotomy for resection of a calcified right ventricular thrombus. At operation an anomalous right ventricular muscle bundle was discovered under the calcified thrombus. Clinical chemistry showed lupus anticoagulant activity and cardiolipin antibodies in the plasma.
Coppock
M A
MA
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota.
Safford
R E
RE
Danielson
G K
GK
D000328:Adult; D001323:Autoantibodies / Q000032:analysis*; D001779:Blood Coagulation Factors / Q000032:analysis / Q000276:immunology; D002308:Cardiolipins / Q000276:immunology*; D005260:Female; D006331:Heart Diseases / Q000209:etiology* / Q000276:immunology; D006352:Heart Ventricles / Q000002:abnormalities*; D006801:Humans; D016682:Lupus Coagulation Inhibitor; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000276:immunology; D013927:Thrombosis / Q000209:etiology* / Q000276:immunology
D001323:Autoantibodies; D001779:Blood Coagulation Factors; D002308:Cardiolipins; D016682:Lupus Coagulation Inhibitor