[Chemoprophylactic activity of soaps containing essential oil from the fruit of Pterodon pubescens in schistosomiasis mansoni].
It has been studied the chemoprophylactic action on experimental schistosomiasis of the essential oil from Pterodon pubescens "sucupira branca" as an additive through different formulations, in toilet soap. Immediately or 24 hours later, groups of mice were exposed by tail method to Schistosoma mansoni cercariae. After 45 days of the exposition, the protective action of these soaps were evaluated. The results showed different levels of protection, ranging from 29.0 to 100.0%. Further studies are on going with the most promising formulations.
Santos Filho
D
D
Faculdade de Ciências Farmacêuticas de Ribeirão Preto, SP, Brasil.
Sarti
S J
SJ
Katz
N
N
Araújo
N
N
Rocha Filho
P A
PA
Abreu
J E
JE
Bortolin
M E
ME
D000818:Animals; D005638:Fruit / Q000032:analysis; D051379:Mice; D010936:Plant Extracts; D010938:Plant Oils / Q000302:isolation & purification / Q000627:therapeutic use*; D012555:Schistosomiasis mansoni / Q000517:prevention & control*; D012915:Soaps; D013501:Surface-Active Agents
D010936:Plant Extracts; D010938:Plant Oils; D012915:Soaps; D013501:Surface-Active Agents
Atividade quimioprofilática de sabonetes contendo óleo essencial de frutos de Pterodon pubescens na esquistossomose mansoni.