Increase of alcohol dehydrogenase and protein content of liver following chronic ethanol administration.
Increased alcohol tolerance following chronic alcohol administration has been explained by increased mitochondrial oxidation of NADH and or increased activation of MEOS. According to our experiments this increased tolerance after chronic alcohol consumption is connected with an increased activity of ADH.
Buris
L
L
Csabai
G
G
Fodor
M
M
Varga
M
M
D000426:Alcohol Dehydrogenase; D000429:Alcohol Oxidoreductases / Q000378:metabolism*; D000437:Alcoholism / Q000201:enzymology*; D000818:Animals; D004247:DNA / Q000378:metabolism; D004361:Drug Tolerance; D000431:Ethanol / Q000008:administration & dosage; D006801:Humans; D008099:Liver / Q000201:enzymology*; D011506:Proteins / Q000378:metabolism*; D051381:Rats
D011506:Proteins; D000431:Ethanol; D004247:DNA; D000429:Alcohol Oxidoreductases; D000426:Alcohol Dehydrogenase