Sarcomatous change in a previously benign osteofibroma in the maxillary sinus.
Ossifying fibromas of the jaws are generally well-defined benign tumors, so that adequate surgical treatment is usually associated with good therapeutic results. However, there are cases--especially in younger individuals with maxillary tumors--in which recurrences are seen, often with aggressive growth and subsequent local destruction. There is no characteristic histological appearance that identifies these "recurring types." A case is presented in which a benign ossifying fibroma was extirpated from a 17-year-old man. Twenty years later a recurrent tumor was found, in which histological examination showed development of a osteosarcoma. The clinical implications of this case are discussed.
Bundgaard
T
T
ENT Department, Aarhus Municipal Hospital, Denmark.
Frost-Jensen
V
V
Buhl
L
L
D000293:Adolescent; D000328:Adult; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D005350:Fibroma / Q000473:pathology*; D006801:Humans; D008297:Male; D008444:Maxillary Sinus Neoplasms / Q000473:pathology*; D010016:Osteoma / Q000473:pathology*; D012516:Osteosarcoma / Q000473:pathology*; D010255:Paranasal Sinus Neoplasms / Q000473:pathology*