title: [Assessment of occupational exposures to industrial hazardous substances. I. A proposed method based on interday fluctuation of contaminant concentrations for evaluating employee's exposure averages (TWAs)].
abstract: Occupational exposures to potentially hazardous substances may vary considerably because of factors such as sampling and analytical errors, and intraday and interday environmental fluctuations in contaminant concentration. Of these factors, day-to-day environmental fluctuations most likely affect daily exposure averages over days, weeks, months or years. A new method based on day-to-day fluctuations of daily exposure averages (geometric standard deviation) was developed for making reliable assessment of the employee's exposure situation. It is assumed that daily exposure averages of a worker are lognormally and independently distributed statistically. Finally, a classification scheme on the basis of n days measurements is presented. 95% upper limit or arithmetic mean of individual exposure averages (8-h TWAs) can be evaluated in comparison with an established standard. The method may provide an approximate estimate because of statistical premise, but it can be utilized for practical purposes, particularly, in case where only one or two days are being monitored. An action level concept based on random sampling and analytical errors and interday variations developed by OSHA/NIOSH, and a sampling and decision scheme based on one-sided tolerance limits proposed by Tuggle (1982) are also discussed.
authors.affiliation: Department of Occupational Health, Osaka Prefectural Institute of Public Health.
authors.forename: I
authors.initials: I
authors.lastname: Matsunaga
authors.forename: S
authors.initials: S
authors.lastname: Kumagai
authors.forename: K
authors.initials: K
authors.lastname: Sugimoto
mesh_terms: D003627:Data Interpretation, Statistical; D004781:Environmental Exposure; D004784:Environmental Monitoring / Q000379:methods*; D015386:Hazardous Substances / Q000032:analysis*; D006801:Humans; D009787:Occupational Medicine
chemical_list: D015386:Hazardous Substances