A linkage study of primary affective disorder.
Marker loci in 113 members of nine unrelated multiplex families identified by a bipolar proband were tested for linkages with primary affective disorder. Linkage was excluded between the disease locus (assuming that it was a single autosomal dominant gene) and the HLA loci at a recombination fraction of 0.2, the ABO, Rh, and Lu loci at almost 0.05 and the Fy and P loci at 0.001.
Waters
B
B
Department of Child and Adolescent Psychiatry, Prince of Wales Hospital, Randwick, New South Wales, Australia.
Sengar
D
D
Marchenko
I
I
Rock
G
G
Lapierre
Y
Y
Forster-Gibson
C J
CJ
Simpson
N E
NE
D000328:Adult; D000368:Aged; D001714:Bipolar Disorder / Q000235:genetics*; D008040:Genetic Linkage; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011995:Recombination, Genetic
D006680:HLA Antigens