title: Response of human immunodeficiency virus-associated uveitis to zidovudine.
abstract: A patient with human immunodeficiency virus (HIV) type 1 infection developed chronic iridocyclitis and anterior vitritis that were poorly responsive to topical and systemic corticosteroid therapy. Anterior chamber paracentesis was performed and HIV was isolated from culture of aqueous humor. Subsequent treatment with oral zidovudine resulted in resolution of the iridocyclitis and vitritis and full functional recovery of the eye. This case suggests that HIV may be a cause of uveitis responsive to systemic zidovudine therapy.
authors.affiliation: Department of Ophthalmology, New York Hospital Cornell Medical Center, NY 10021.
authors.forename: P L
authors.initials: PL
authors.lastname: Farrell
authors.forename: M H
authors.initials: MH
authors.lastname: Heinemann
authors.forename: C W
authors.initials: CW
authors.lastname: Roberts
authors.forename: B
authors.initials: B
authors.lastname: Polsky
authors.forename: J W
authors.initials: JW
authors.lastname: Gold
authors.forename: A
authors.initials: A
authors.lastname: Mamelok
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000284:Administration, Oral; D000328:Adult; D006801:Humans; D008297:Male; D013936:Thymidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D014605:Uveitis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D014792:Visual Acuity; D015215:Zidovudine
chemical_list: D015215:Zidovudine; D013936:Thymidine