title: Human beta-globin gene HpaI polymorphism in the non-white Cuban population.
abstract: The frequency of the association between the beta A, beta S and the beta C genes with the 13.0 kb HpaI restriction fragment has been determined in 72 non-white individuals with different hemoglobin phenotypes giving a value of 0.00 for the beta A gene, 0.52 for the beta S gene and 1.00 for the beta C gene. These data indicate that this association in the Cuban non-white population is similar to that reported for the American Blacks living in the U.S.A. East Coast and for the French West Indies.
authors.affiliation: Instituto de Hematología e Immunología, La Habana, Cuba.
authors.forename: G
authors.initials: G
authors.lastname: Martinez
authors.forename: R
authors.initials: R
authors.lastname: Ferreira
authors.forename: B
authors.initials: B
authors.lastname: Colombo
mesh_terms: D000293:Adolescent; D000328:Adult; D000349:Africa / Q000208:ethnology; D000755:Anemia, Sickle Cell / Q000235:genetics; D002648:Child; D003462:Cuba; D015252:Deoxyribonucleases, Type II Site-Specific; D005260:Female; D005787:Gene Frequency; D005914:Globins / Q000235:genetics*; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic; D044465:White People / Q000235:genetics
chemical_list: D005914:Globins; C024406:endodeoxyribonuclease HpaI; D015252:Deoxyribonucleases, Type II Site-Specific