Cytochemical detection of estrogen receptors in mammary tumours.
The technical details of a cytochemical method for estrogen receptor identification in mammary tumours are presented and applied in 19 carcinomas and six adenofibromas. A fluorescent estradiol conjugate was used as receptor tracer. From the 19 mammary carcinomas, six were interpreted as estrogen receptor-negative (ER-), two were strongly receptor-positive (ER++) and eleven were moderately estrogen receptor-positive (ER+), having cells with a heterogeneous content of estrogen receptors. In fibroadenomas, the proliferating epithelia were moderately estrogen-receptor positive.
Gădăleanu
V
V
Gavrilescu
T H
TH
D000232:Adenofibroma / Q000378:metabolism*; D001943:Breast Neoplasms / Q000378:metabolism*; D002277:Carcinoma / Q000378:metabolism*; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D008856:Microscopy, Fluorescence; D011960:Receptors, Estrogen / Q000378:metabolism*
D011960:Receptors, Estrogen