Recurrence rate after successful coronary angioplasty.
Among 356 consecutive patients with successful TCA performed between October 1977 and June 1983 follow-up angiograms were performed in 333 patients (94%). A total of 439 follow-up angiograms at 1-48 (average 5.6) months after successful angioplasty were analysed. Restenosis rate was 12% if defined as remaining widening of less than 20% compared with the situation before angioplasty. It was 16% if defined as loss of at least half of the initial gain in luminal diameter, and 17% if defined as increase from immediate post-TCA-stenosis of much greater than 30% or the loss of at least half of the initial gain in luminal diameter. This value dropped to 15% if the subgroup of 30 patients with second TCA and of 14 patients with dilatation of an aortocoronary bypass stenosis were excluded; in both subgroups recurrence rate was higher (33% and 45%, respectively). The observed restenosis rate is less than 50% of that reported by the PTCA registry of the NHLBI. Several factors can possibly be responsible for the reduction in restenosis rate: selection of patients; technique of TCA; medical treatment during and after TCA; modification of risk factors, compliance of patients; unknown factors. Long-term medical treatment with acetyl salicylic acid, nitrates and calcium blockers in high doses is considered to be most probably responsible for the favourable results.
Kaltenbach
M
M
Kober
G
G
Scherer
D
D
Vallbracht
C
C
D000792:Angiography; D000800:Angioplasty, Balloon; D001241:Aspirin / Q000627:therapeutic use; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003251:Constriction, Pathologic / Q000628:therapy; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000628:therapy*; D003331:Coronary Vessels; D005500:Follow-Up Studies; D006801:Humans; D007548:Isosorbide Dinitrate / Q000627:therapeutic use; D012008:Recurrence; D013997:Time Factors
D002121:Calcium Channel Blockers; D007548:Isosorbide Dinitrate; D001241:Aspirin