title: Ovarian sarcoma with histologic features of telangiectatic osteosarcoma of the bone.
abstract: A primary osteosarcoma occurred in the left ovary of a 47-year-old Japanese woman. The preoperative diagnosis, based on computerized tomography, was cystic teratoma. The excised tumor was composed of large multilocular cysts containing blood and associated with an area of solid tissue. Histologically, the tumor was a "pure" osteosarcoma that showed prominent cellular anaplasia and blood-filled spaces lined with tumor cells. The lesion resembled a telangiectatic osteosarcoma of bone. Serum alkaline phosphatase levels reflected progression of the disease. Despite aggressive adjuvant chemotherapy, the patient died 8 months later of a local recurrence and intra-abdominal spread of the tumor.
authors.affiliation: Second Department of Pathology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Hirakawa
authors.forename: M
authors.initials: M
authors.lastname: Tsuneyoshi
authors.forename: M
authors.initials: M
authors.lastname: Enjoji
authors.forename: R
authors.initials: R
authors.lastname: Shigyo
mesh_terms: D001859:Bone Neoplasms / Q000098:blood supply* / Q000150:complications / Q000473:pathology; D005260:Female; D006485:Hemosiderin / Q000378:metabolism; D006801:Humans; D008875:Middle Aged; D012516:Osteosarcoma / Q000098:blood supply* / Q000150:complications / Q000473:pathology; D010051:Ovarian Neoplasms / Q000473:pathology*; D012509:Sarcoma / Q000473:pathology*; D013684:Telangiectasis / Q000150:complications / Q000473:pathology*
chemical_list: D006485:Hemosiderin