[Reception of aldosterone by the rat kidney in its compensatory hypertrophy].
A study was made of the effect of the compensatory hypertrophy of the rat kidney (on the 30th day) on the interaction of 3H-aldosterone with the receptors of the kidney cell tubules. It has been shown that the compensatory hypertrophy of the kidney is accompanied by an increased intensity of 3H-aldosterone binding with the receptors of the nephron cell cytoplasm and a decrease of the transfer of the hormonoreceptor cytoplasm and 3 receptor complex to the nucleus. These changes in the mechanism of aldosterone reception by the hypertrophic kidney can be accompanied by disturbed sensitivity of the organ to this mineralocorticoid.
Akimov
Iu A
IuA
Azhipa
Ia I
IaI
Rodionov
A A
AA
D000222:Adaptation, Physiological; D000450:Aldosterone / Q000378:metabolism*; D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism*; D003593:Cytoplasm / Q000378:metabolism*; D006984:Hypertrophy; D007684:Kidney Tubules / Q000473:pathology / Q000648:ultrastructure*; D008297:Male; D009392:Nephrectomy; D051381:Rats; D011965:Receptors, Glucocorticoid / Q000378:metabolism*; D018161:Receptors, Mineralocorticoid; D011987:Receptors, Steroid / Q000378:metabolism*; D013997:Time Factors
D011965:Receptors, Glucocorticoid; D018161:Receptors, Mineralocorticoid; D011987:Receptors, Steroid; D000450:Aldosterone
O retseptsii al'dosterona pochkoĭ krys pri kompensatornoĭ gipertrofii organa.