title: [Surgical aortic valve replacement for acute Streptococcus viridans endocarditis with simultaneous moderate hemophilia A].
abstract: This is a report of a 25-year-old patient with known aortic valve stenosis since early youth and hemophilia A, showing recurrent joint bleeding. Acute Streptococcus endocarditis induced aortic valve insufficiency resulting in cardiac failure. Aortic valve replacement was performed after substitution of factor VIII, during which intra- and postoperative bleeding was prolonged by pericardial adhesions. Heparin was administered during cardiopulmonary-bypass as usual, but usual postoperative cumarin therapy was not initiated due to prolonged PTT time. One year postoperatively, the patient was in an excellent condition and fully rehabilitated.
authors.affiliation: I. Medizinische Klinik, Ludwig-Maximilians-Universität München.
authors.forename: W
authors.initials: W
authors.lastname: Krawietz
authors.forename: C
authors.initials: C
authors.lastname: Loracher
authors.forename: E
authors.initials: E
authors.lastname: Struck
authors.forename: G
authors.initials: G
authors.lastname: Schlimok
authors.forename: H
authors.initials: H
authors.lastname: Falk
mesh_terms: D000328:Adult; D001022:Aortic Valve Insufficiency / Q000097:blood / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000097:blood / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D004697:Endocarditis, Bacterial / Q000097:blood / Q000601:surgery*; D005169:Factor VIII / Q000008:administration & dosage; D006350:Heart Valve Prosthesis; D006467:Hemophilia A / Q000097:blood*; D006801:Humans; D008297:Male; D010314:Partial Thromboplastin Time; D013290:Streptococcal Infections / Q000097:blood / Q000601:surgery*
chemical_list: D005169:Factor VIII
vernacular_title: Operativer Aortenklappenersatz wegen akuter Streptococcus-viridans-Endokarditis bei gleichzeitig bestehender mittelschwerer Hämophilie A.