title: Effect of diclofenac sodium (Voltaren) on spermatogenesis of infertile oligospermic patients.
abstract: The effect of the prostaglandin synthesis inhibitor diclofenac sodium (Voltaren) on spermatogenesis in infertile oligospermic patients has been studied. Diclofenac sodium was given orally at a daily dose of 100 mg for 30 days. Seminal fluid parameters were evaluated. Group II with high levels of seminal prostaglandin showed a statistically significant increase in the number and motility of spermatozoa (p less than 0.01), whilst no significant variations were observed in patients of group I with normal values of seminal prostaglandin.
authors.affiliation: Department of Urology, Rambam Medical Center, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa.
authors.forename: B
authors.initials: B
authors.lastname: Moskovitz
authors.forename: R
authors.initials: R
authors.lastname: Lin
authors.forename: S
authors.initials: S
authors.lastname: Nassar
authors.forename: D R
authors.initials: DR
authors.lastname: Levin
mesh_terms: D000328:Adult; D004008:Diclofenac / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009845:Oligospermia / Q000188:drug therapy*; D011453:Prostaglandins / Q000032:analysis; D012661:Semen / Q000032:analysis; D013091:Spermatogenesis / Q000187:drug effects*
chemical_list: D011453:Prostaglandins; D004008:Diclofenac