title: Chronic recurrent multifocal osteomyelitis in children. A roentgenologic and scintigraphic investigation.
abstract: Thirty cases of chronic recurrent multifocal osteomyelitis have been reported in the literature. A radiologic evaluation of thirty-one additional cases, 25 of whom also underwent bone scintigraphy, is presented. Bone biopsy specimens were obtained in 16 patients. Most lesions were located in the metaphyses of the long bones adjacent to the physis and had a characteristic, probably pathognomonic appearance. Extension into the epiphyses was rare. Lesions in the vertebral bodies, clavicle and pelvis had possibly a less specific radiographic appearance. Lesions in short tubular bones were non-specific. Bone scintigraphy had a practical value in evaluating the global distribution of lesions including asymptomatic lesions and lesions in the spine or pelvis, the latter being somewhat hard to detect with conventional radiography. All biopsies showed acute, subacute or chronic unspecific osteomyelitis, sometimes mixed in the same lesion. Staining for bacteria and fungi was negative.
authors.affiliation: Department of Pediatric Radiology, St. Göran's Children's Hospital, Stockholm, Sweden.
authors.forename: W
authors.initials: W
authors.lastname: Mortensson
authors.forename: G
authors.initials: G
authors.lastname: Edeburn
authors.forename: M
authors.initials: M
authors.lastname: Fries
authors.forename: R
authors.initials: R
authors.lastname: Nilsson
mesh_terms: D000293:Adolescent; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D002968:Clavicle / Q000000981:diagnostic imaging; D005260:Female; D006132:Growth Plate / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D010019:Osteomyelitis / Q000000981:diagnostic imaging*; D010388:Pelvis / Q000000981:diagnostic imaging; D011859:Radiography; D011877:Radionuclide Imaging; D012008:Recurrence; D013131:Spine / Q000000981:diagnostic imaging