Preclinical and clinical effects of the hematopoietic colony stimulating factors.
Hematopoietic colony stimulating factors are available in purified recombinant form and have used for assessment of hematopoietic activities in mice, monkeys and in phase I clinical trials with humans. This report reviews the preclinical and clinical studies involving these factors.
Broxmeyer
H E
HE
Department of Medicine (Hematology/Oncology), Indiana University School of Medicine, Indianapolis.
Vadhan-Raj
S
S
Hangoc
G
G
Lu
L
L
Gutterman
J U
JU
Williams
D E
DE
D000818:Animals; D003115:Colony-Stimulating Factors / Q000494:pharmacology*; D004341:Drug Evaluation; D004921:Erythropoietin / Q000494:pharmacology; D000882:Haplorhini; D006410:Hematopoiesis / Q000187:drug effects*; D006801:Humans; D051379:Mice; D011994:Recombinant Proteins / Q000494:pharmacology
D003115:Colony-Stimulating Factors; D011994:Recombinant Proteins; D004921:Erythropoietin