Characterization of T cell subsets in patients with atopic dermatitis using OKT monoclonal antibodies.
The distribution of T cell subsets has been studied by means of OKT monoclonal antibodies in 19 children with atopic dermatitis. In these patients a decreased percentage of circulating OKT4+ cells has been observed, while no difference has been found between atopic and normal subjects, regarding the percentages of circulating OKT8+ and OKT11+ cells. An increased OKT4+/OKT8+ ratio has been detected only in three children with a particularly severe and extensive atopic eczema.
Miadonna
A
A
Tedeschi
A
A
Leggieri
E
E
Cottini
M
M
Menni
S
S
Froldi
M
M
Zanussi
C
C
D000293:Adolescent; D000911:Antibodies, Monoclonal; D000918:Antibody Specificity; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000276:immunology*; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007223:Infant; D008297:Male; D013601:T-Lymphocytes / Q000145:classification*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology
D000911:Antibodies, Monoclonal; D007073:Immunoglobulin E