title: Monosomy 5 in acute megakaryoblastic leukemia. Report of two cases.
abstract: Two cases of acute megakaryoblastic leukemia are reported. The diagnoses were confirmed by clinical, morphologic, and cytochemical analysis. Karyotypic analysis demonstrated monosomy 5 in both patients, providing further evidence that acute megakaryoblastic leukemia is a subset of the acute nonlymphocytic leukemias and may be etiologically related to the myelodysplastic syndromes.
authors.affiliation: Don Monti Division of Oncology, North Shore University Hospital, Manhasset, New York 11030.
authors.forename: S
authors.initials: S
authors.lastname: Lichtman
authors.forename: P
authors.initials: P
authors.lastname: Schulman
authors.forename: N
authors.initials: N
authors.lastname: Kardon
authors.forename: S L
authors.initials: SL
authors.lastname: Allen
authors.forename: M
authors.initials: M
authors.lastname: Susin
mesh_terms: D000328:Adult; D002872:Chromosome Deletion; D002895:Chromosomes, Human, Pair 5; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D007947:Leukemia, Megakaryoblastic, Acute / Q000235:genetics* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009006:Monosomy
chemical_list: D005819:Genetic Markers