title: Immunological alterations in a case of Papillon-Lefèvre syndrome with recurrent cutaneous infections.
abstract: An immunological study was performed in a 16-year-old boy affected with Papillon-Lefèvre syndrome (PLS) and recurrent staphylococcal cutaneous infections. A defect of neutrophil intracellular killing of Staphylococcus aureus and a decreased lymphocyte proliferative response to phytohaemagglutinin were detected. The possible role of these alterations in promoting recurrent infections in PLS is discussed.
authors.forename: G
authors.initials: G
authors.lastname: Borroni
authors.forename: A
authors.initials: A
authors.lastname: Pagani
authors.forename: A
authors.initials: A
authors.lastname: Carcaterra
authors.forename: R
authors.initials: R
authors.lastname: Pericoli
authors.forename: P
authors.initials: P
authors.lastname: Gabba
authors.forename: M
authors.initials: M
authors.lastname: Marconi
mesh_terms: D000293:Adolescent; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000276:immunology*; D008297:Male; D009504:Neutrophils / Q000276:immunology; D010214:Papillon-Lefevre Disease / Q000276:immunology*; D012008:Recurrence; D012874:Skin Diseases, Infectious / Q000276:immunology*; D013203:Staphylococcal Infections / Q000276:immunology