title: Non-A, non-B hepatitis-related hepatocellular carcinoma in a chimpanzee.
abstract: Epidemiology has indicated the possible association of non-A, non-B hepatitis (NANBH) with hepatocellular carcinoma (HCC) in man, but there are no means for confirmation. Chimpanzees are recognized models for studying hepatitis B and NANBH, and may become carriers of both. The first case of HCC to be reported in chimpanzees was found after longitudinal study of a hepatitis B-free chimpanzee 7 years after inoculation with human plasma from a patient reported to have chronic NANBH.
authors.affiliation: Laboratory for Experimental Medicine and Surgery in Primates (LEMSIP) New York University Medical Center, Tuxedo 10987.
authors.forename: E
authors.initials: E
authors.lastname: Muchmore
authors.forename: H
authors.initials: H
authors.lastname: Popper
authors.forename: D A
authors.initials: DA
authors.lastname: Peterson
authors.forename: M F
authors.initials: MF
authors.lastname: Miller
authors.forename: H M
authors.initials: HM
authors.lastname: Lieberman
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D006526:Hepatitis C / Q000150:complications* / Q000276:immunology; D006525:Hepatitis, Viral, Human / Q000150:complications*; D008113:Liver Neoplasms / Q000209:etiology*; D008114:Liver Neoplasms, Experimental / Q000209:etiology*; D008137:Longitudinal Studies; D008854:Microscopy, Electron; D002679:Pan troglodytes