TRH-induced prolactin release in unipolar depressed patients and controls.
We compared unipolar depressed patients (N = 32) with normal controls (N = 38) for their prolactin responses on the thyrotropin releasing hormone test. Depressed patients showed prolactin responses similar to sex matched controls. Among the depressed patients there were no significant differences for prolactin response between those with or without a blunted thyroid stimulating hormone response, dexamethasone suppressors or nonsuppressors, or between melancholic and nonmelancholic depressive subgroups.
Roy
A
A
Section on Clinical Studies, National Institute of Mental Health, Bethesda, MD 20892.
Pickar
D
D
D000328:Adult; D003866:Depressive Disorder / Q000097:blood / Q000175:diagnosis*; D003907:Dexamethasone; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008875:Middle Aged; D011388:Prolactin / Q000097:blood*; D013972:Thyrotropin / Q000097:blood; D013973:Thyrotropin-Releasing Hormone
D013973:Thyrotropin-Releasing Hormone; D003907:Dexamethasone; D011388:Prolactin; D013972:Thyrotropin; D006854:Hydrocortisone