[Delta sleep-inducing peptide in the blood and hypothalamus of rats with various resistance to emotional stress].
Enzyme immunoassay was used to study delta-sleep peptide content in blood and hypothalamus in rats of Wistar lines under acute emotional stress. It was found that the content of delta-sleep peptide in blood and hypothalamus of stable rats was higher as compared with rats predisposed to emotional stress. After 1.5-hour emotional stress the content of delta-sleep peptide increased in blood and hypothalamus both in stable rats and predisposed ones. After 3-hour stress there was an increase in delta-sleep peptide content in hypothalamus, and contrary to its decrease in blood in both stable and predisposed animals. It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
Salieva
R M
RM
Koplik
E V
EV
Kamenov
Z A
ZA
Poletaev
A B
AB
D000818:Animals; D003701:Delta Sleep-Inducing Peptide / Q000097:blood / Q000378:metabolism / Q000502:physiology*; D004198:Disease Susceptibility; D007031:Hypothalamus / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013315:Stress, Psychological / Q000097:blood / Q000378:metabolism / Q000503:physiopathology*
D003701:Delta Sleep-Inducing Peptide
Peptid, vyzyvaiushchiĭ del'ta-son, v krovi i gipotalamuse u krys s razlichnoĭ ustoĭchivost'iu k émotsional'nomu stressu.