title: Trisomy 4 in a case of acute nonlymphocytic leukemia (M2).
abstract: Trisomy 4 in a Japanese patient with type M2 acute nonlymphocytic leukemia is reported. Karyotypic analysis was unsuccessful at diagnosis and complete remission lasted 4 years. The cytogenetic change was detected in the first and second relapses as the only chromosome abnormality. Unusual nuclear irregularities were found in many leukemic cells.
authors.affiliation: Department of Medicine, Kochi Medical School, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Fujishita
authors.forename: T
authors.initials: T
authors.lastname: Miyagi
authors.forename: T
authors.initials: T
authors.lastname: Takeuchi
authors.forename: I
authors.initials: I
authors.lastname: Kubonishi
authors.forename: K
authors.initials: K
authors.lastname: Niiya
authors.forename: H
authors.initials: H
authors.lastname: Taguchi
authors.forename: Y
authors.initials: Y
authors.lastname: Ohtsuki
authors.forename: I
authors.initials: I
authors.lastname: Miyoshi
mesh_terms: D000208:Acute Disease; D000328:Adult; D002894:Chromosomes, Human, Pair 4; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D007938:Leukemia / Q000235:genetics* / Q000473:pathology; D014314:Trisomy
chemical_list: D005819:Genetic Markers