A study of several red cell enzyme markers in two samples of the Italian population. Report of new CA1 and PGD variant phenotypes.
Gene frequencies for 17 red cell enzymatic markers have been determined in two samples of the Italian population (Lombardy and Tuscany regions). A significant difference was found between the two samples for the AK1 and PGM1 systems (AK1*2 .028 and .044, PGM1*2 .254 and .301 in Lombardy and Tuscany respectively). Variant phenotypes, for PEPA, PEPB, CA2, PGM2, PGD and GPT markers, have been observed; some of these are due to new alleles occurring at the CA2 and PGD loci.
Barberio
C
C
Dipartimento di Biologia Animale e Genetica, Univ. Firenze, Italy.
Ranzani
G N
GN
Beretta
M
M
Antonini
G
G
Mura
G
G
Pardini
R
R
Zanella
A
A
Santachiara-Benerecetti
A S
AS
D000483:Alleles; D002256:Carbonic Anhydrases / Q000235:genetics*; D004798:Enzymes / Q000235:genetics*; D004912:Erythrocytes; D005787:Gene Frequency; D005819:Genetic Markers; D006801:Humans; D007558:Italy; D010641:Phenotype; D010734:Phosphogluconate Dehydrogenase / Q000235:genetics*; D011110:Polymorphism, Genetic
D004798:Enzymes; D005819:Genetic Markers; D010734:Phosphogluconate Dehydrogenase; D002256:Carbonic Anhydrases