Protection against noise trauma by pre-exposure to a low level acoustic stimulus.
Guinea pigs were pre-exposed to a low level acoustic stimulus prior to exposure to a stimulus known to yield a permanent threshold shift. This pre-treatment resulted in: 1) approximately a 20 dB reduction in the threshold shift relative to animals not pre-exposed, and 2) complete recovery from the threshold shift after 2 months.
Canlon
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B
Department of Physiology II, Karolinska Institute, Stockholm, Sweden.
Borg
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E
Flock
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A
D000161:Acoustic Stimulation; D000818:Animals; D001305:Auditory Fatigue / Q000502:physiology; D001309:Auditory Threshold / Q000502:physiology; D005072:Evoked Potentials, Auditory; D006168:Guinea Pigs; D006317:Hearing Loss, Noise-Induced / Q000503:physiopathology* / Q000517:prevention & control