title: Rex-induced recombination implies bipolar organization of the ribosomal RNA genes of Drosophila melanogaster.
abstract: Rex-induced mitotic recombination was used to determine whether nucleolus organizers can pair in both inverted and noninverted orientations. Two target chromosomes, each duplicated for the rDNA region, were exposed to maternal Rex activity. Recombination in one orientation should yield deletion of the material between the two nucleolus organizers, recombination in the other orientation should yield inversion of the same material. Both products were recovered from both target chromosomes. The generality of using Rex-mediated recombination for analysis of the rDNA is considered.
authors.affiliation: Department of Zoology, Michigan State University, East Lansing 48824.
authors.forename: L G
authors.initials: LG
authors.lastname: Robbins
authors.forename: E E
authors.initials: EE
authors.lastname: Swanson
mesh_terms: D000818:Animals; D007446:Chromosome Inversion; D003433:Crosses, Genetic; D003434:Crossing Over, Genetic; D004275:DNA, Ribosomal / Q000235:genetics; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D005796:Genes; D008297:Male; D009697:Nucleolus Organizer Region; D012335:RNA, Ribosomal / Q000235:genetics*; D011995:Recombination, Genetic; D012091:Repetitive Sequences, Nucleic Acid; D014960:X Chromosome
chemical_list: D004275:DNA, Ribosomal; D012335:RNA, Ribosomal