Histochemical and biochemical alterations in skeletal muscles of rats during combined chronic hypoxia and hypokinesia.
This investigation was designed to study the long term effect of combined hypokinesia and hypoxia on the skeletal muscle. In the muscles of the hypoxic and hypokinetic animals, serious degenerative changes were found and the fibre type ratio was alterated. The malate dehydrogenase activity was decreased, and both LDH and MDH isoenzymes pattern were alterated.
Józsa
L
L
Vándor
E
E
Demel
S
S
Rapcsák
M
M
Réffy
A
A
Szöör
A
A
Hideg
J
J
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D008058:Dihydrolipoamide Dehydrogenase / Q000378:metabolism; D006651:Histocytochemistry; D000860:Hypoxia / Q000201:enzymology / Q000473:pathology*; D007103:Immobilization; D007527:Isoenzymes / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008291:Malate Dehydrogenase / Q000378:metabolism; D008297:Male; D009124:Muscle Proteins / Q000378:metabolism; D009132:Muscles / Q000201:enzymology / Q000473:pathology*; D051381:Rats; D011919:Rats, Inbred Strains
D007527:Isoenzymes; D009124:Muscle Proteins; D007770:L-Lactate Dehydrogenase; D008291:Malate Dehydrogenase; D008058:Dihydrolipoamide Dehydrogenase; D000251:Adenosine Triphosphatases