title: Neuroticism and personality disorder in depression.
abstract: Neuroticism and DSM-III personality disorder were studied in 39 depressed inpatients. Interrelationships between these variables and their relationship to depressive typology were compared. The relationship of neuroticism, DSM-III personality type and adequacy of personality to MAOI treatment are also examined. Neuroticism scores were unaffected by short-term treatment, and no differences in neuroticism were observed between melancholics and nonmelancholics, or between endogenous and nonendogenous depressives. Higher neuroticism scores were associated with DSM-III personality disorder. Personality disorder occurred significantly more often in nonmelancholia; borderline, antisocial and histrionic personality disorders occurred exclusively in nonmelancholia, while passive-aggressive, dependent and avoidant disorders occurred in both kinds of depression. Response to MAO inhibitor treatment was similar in patients with high and low neuroticism, adequate and inadequate personality, DSM-III personality disorder and no DSM-III personality disorder. Ambiguities of Eysenck's neuroticism scale are discussed in relationship to depression.
authors.forename: J
authors.initials: J
authors.lastname: Davidson
authors.forename: R
authors.initials: R
authors.lastname: Miller
authors.forename: R
authors.initials: R
authors.lastname: Strickland
mesh_terms: D000987:Antisocial Personality Disorder / Q000150:complications; D001883:Borderline Personality Disorder / Q000150:complications; D003866:Depressive Disorder / Q000150:complications* / Q000188:drug therapy / Q000523:psychology; D006677:Histrionic Personality Disorder / Q000150:complications; D006801:Humans; D008370:Manuals as Topic; D008996:Monoamine Oxidase Inhibitors / Q000627:therapeutic use*; D009497:Neurotic Disorders / Q000150:complications*; D010554:Personality Disorders / Q000150:complications*; D010555:Personality Inventory
chemical_list: D008996:Monoamine Oxidase Inhibitors