Stimulation of transcription from accurate initiation sites by purified S-II.
The effects of transcription factors S-II and S-II', a phosphorylated form of S-II, on accurate transcription were compared in a reconstituted transcription system greatly depleted of S-II. S-II, but not S-II', stimulated the syntheses of run-off products of various truncated class II genes in this system, suggesting that the activity of this factor is regulated by its phosphorylation and dephosphorylation.
Hirai
H
H
Faculty of Pharmaceutical Sciences, University of Tokyo, Japan.
Sekimizu
K
K
Horikoshi
M
M
Nakanishi
Y
Y
Natori
S
S
D000260:Adenoviruses, Human / Q000235:genetics; D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000235:genetics*; D007700:Kinetics; D051379:Mice; D009363:Neoplasm Proteins / Q000378:metabolism*; D014157:Transcription Factors / Q000302:isolation & purification / Q000378:metabolism*; D035165:Transcription Factors, General; D014158:Transcription, Genetic; D035602:Transcriptional Elongation Factors
D009363:Neoplasm Proteins; D014157:Transcription Factors; D035165:Transcription Factors, General; D035602:Transcriptional Elongation Factors; C018648:transcription factor S-II