title: Paradoxical precipitation of tonic seizures by lorazepam in a child with atypical absence seizures.
abstract: A 10-year-old girl with Lennox-Gastaut syndrome who received intravenous lorazepam for atypical absence status seizures is reported. Tonic seizures occurred immediately and appeared to represent a paradoxical seizure exacerbation. We also review other patients with paradoxical seizure exacerbation by benzodiazepines.
authors.affiliation: Division of Neurology, Children's Hospital of Philadelphia, Pennsylvania.
authors.forename: F J
authors.initials: FJ
authors.lastname: DiMario
authors.forename: R R
authors.initials: RR
authors.lastname: Clancy
mesh_terms: D002648:Child; D004832:Epilepsy, Absence / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008140:Lorazepam / Q000009:adverse effects*; D013226:Status Epilepticus / Q000139:chemically induced* / Q000503:physiopathology
chemical_list: D008140:Lorazepam