title: [Distribution and extent of hemophilic arthropathy in adulthood in severe factor VIII deficiency].
abstract: This study deals with the distribution and extent of hemophilic arthropathy in 52 adult patients suffering from severe hemophilia A. A clinical and radiological score-evaluation of knee, ankle and elbow joints was undertaken, 4.7 of 6 examined joints proved to be affected in the third life-decade in the average, the extent of destruction being most pronounced at the knee joints. A rather close correlation of clinical and radiological signs was found to exist only related to the knee joints.
authors.affiliation: Orthopädische Poliklinik d. LMU München.
authors.forename: J
authors.initials: J
authors.lastname: Hamel
authors.forename: H
authors.initials: H
authors.lastname: Pohlmann
authors.forename: W
authors.initials: W
authors.lastname: Schramm
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001175:Arthrography; D005169:Factor VIII / Q000627:therapeutic use; D006395:Hemarthrosis / Q000000981:diagnostic imaging*; D006467:Hemophilia A / Q000000981:diagnostic imaging* / Q000628:therapy; D006801:Humans; D007592:Joint Diseases / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D009133:Muscular Atrophy / Q000000981:diagnostic imaging
chemical_list: D005169:Factor VIII
vernacular_title: Verteilung und Ausmass der Hämophilie-Arthropathie im Erwachsenenalter bei schwerem Faktor-VIII-Mangel.