title: Atrial natriuretic factor.
abstract: Mammalian atria contain different peptides with potent diuretic, natriuretic, smooth muscle relaxing and blood pressure lowering properties. A preprohormone of these peptides is synthetized and stored in specific granules in atrial myocytes. Different peptides have been isolated, analyzed and in vitro synthetized. Their biological activity indicates a potential role in the regulation of volume and sodium homeostasis as well as in blood pressure regulation.
authors.forename: R
authors.initials: R
authors.lastname: Palluk
authors.forename: W
authors.initials: W
authors.lastname: Gaida
authors.forename: W
authors.initials: W
authors.lastname: Hoefke
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D009320:Atrial Natriuretic Factor; D004232:Diuretics; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007668:Kidney / Q000098:blood supply / Q000187:drug effects; D009124:Muscle Proteins / Q000378:metabolism / Q000494:pharmacology / Q000502:physiology; D009318:Natriuresis / Q000187:drug effects; D011487:Protein Conformation; D011498:Protein Precursors; D012084:Renin-Angiotensin System / Q000187:drug effects
chemical_list: D004232:Diuretics; D009124:Muscle Proteins; D011498:Protein Precursors; D009320:Atrial Natriuretic Factor