Are different pharmacokinetic properties of lidocaine versus propafenone in normal as compared to ischemic myocardium responsible for different electrophysiologic effects which help preventing arrhythmias?
Puddu
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Rouet
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D000818:Animals; D001145:Arrhythmias, Cardiac / Q000517:prevention & control*; D003326:Coronary Circulation; D004594:Electrophysiology; D006168:Guinea Pigs; D066298:In Vitro Techniques; D008012:Lidocaine / Q000493:pharmacokinetics* / Q000627:therapeutic use; D009203:Myocardial Infarction / Q000378:metabolism* / Q000503:physiopathology; D009206:Myocardium / Q000378:metabolism*; D011405:Propafenone / Q000493:pharmacokinetics* / Q000627:therapeutic use
D011405:Propafenone; D008012:Lidocaine