title: Types and distribution of glutamic acid decarboxylase (GAD)-immunoreactive neurons in mouse motor cortex.
abstract: Neuronal structures in mouse motor cortex that contain gamma-aminobutyric acid (GABA), were identified by an immunocytochemical method, using an antiserum to glutamic acid decarboxylase (GAD). GAD-positive cell bodies occurred in all layers of the motor cortex, but were more concentrated in layers III and VI. GAD-positive puncta, presumably axon terminals, were also distributed throughout the cortical layers; a high density of puncta occurred in layer III, whereas a somewhat lower density characterized layer VI. Based on the shapes of their somata and dendritic trees we concluded that all GAD-positive cells were of the non-pyramidal type.
authors.affiliation: Department of Morphology, Ben-Gurion University of the Negev, Beer Sheva, Israel.
authors.forename: Y
authors.initials: Y
authors.lastname: Solberg
authors.forename: E L
authors.initials: EL
authors.lastname: White
authors.forename: A
authors.initials: A
authors.lastname: Keller
mesh_terms: D000818:Animals; D005968:Glutamate Decarboxylase / Q000032:analysis*; D007150:Immunohistochemistry; D008297:Male; D051379:Mice; D009044:Motor Cortex / Q000201:enzymology*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
chemical_list: D005680:gamma-Aminobutyric Acid; D005968:Glutamate Decarboxylase