title: Oral submucous fibrosis--a new treatment regimen.
abstract: Successful treatment of oral submucous fibrosis with local injections of chymotrypsin, hyaluronidase, and dexamethasone is reported. In resistant cases, surgical excision of the fibrotic bands with submucosal placement of fresh human placental grafts was found to be successful.
authors.affiliation: Department of Otorhinolaryngology, J.N. Medical College, Aligarh Muslim University, India.
authors.forename: D
authors.initials: D
authors.lastname: Gupta
authors.forename: S C
authors.initials: SC
authors.lastname: Sharma
mesh_terms: D002918:Chymotrypsin / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003907:Dexamethasone / Q000627:therapeutic use; D006801:Humans; D006821:Hyaluronoglucosaminidase / Q000627:therapeutic use; D009059:Mouth Diseases / Q000188:drug therapy*; D009914:Oral Submucous Fibrosis / Q000188:drug therapy*; D010920:Placenta / Q000637:transplantation; D010924:Placental Extracts / Q000627:therapeutic use; D011897:Random Allocation
chemical_list: D010924:Placental Extracts; D003907:Dexamethasone; D006821:Hyaluronoglucosaminidase; D002918:Chymotrypsin