Eicosanoids and skin.
A better understanding of the physiological and pathological roles of lipoxygenase metabolites on skin will be obtained with the development of safe and specific 5- and 12-lipoxygenase inhibitors. Lipocortins have been cloned and the results of clinical trials with them should provide further insight into the mechanism(s) of action of steroids on skin diseases.
De Nucci
G
G
William Harvey Research Institute, St Bartholomew's Hospital Medical College, London, U.K.
D004537:Eicosanoic Acids / Q000502:physiology*; D006801:Humans; D008084:Lipoxygenase / Q000378:metabolism; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism; D012867:Skin / Q000503:physiopathology; D012871:Skin Diseases / Q000503:physiopathology; D012879:Skin Physiological Phenomena
D004537:Eicosanoic Acids; D008084:Lipoxygenase; D011451:Prostaglandin-Endoperoxide Synthases