Fatal multisystemic toxicity associated with prophylaxis with pyrimethamine and sulfadoxine (Fansidar).
Selby
C D
CD
Ladusans
E J
EJ
Smith
P G
PG
D056486:Chemical and Drug Induced Liver Injury; D004338:Drug Combinations / Q000009:adverse effects; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced*; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000473:pathology; D008288:Malaria / Q000517:prevention & control*; D008875:Middle Aged; D011739:Pyrimethamine / Q000009:adverse effects*; D013413:Sulfadoxine / Q000009:adverse effects*; D013424:Sulfanilamides / Q000009:adverse effects*
D004338:Drug Combinations; D013424:Sulfanilamides; C001205:fanasil, pyrimethamine drug combination; D013413:Sulfadoxine; D011739:Pyrimethamine