title: [The composition of immune sera against Neisseria meningitidis studied by high-performance liquid chromatography].
abstract: The comparative study of the composition of immune rabbit sera to N. meningitidis, as well as nonimmune sera, has been made by the methods of HPLC and radial immunodiffusion. The quantitative evaluation of the main serum proteins by the two methods has shown the coincidence of the results yielded by these methods. To study the total level of IgM and IgG in the sera under study, a simple and rapid HPLC technique is proposed. The study of the stability of sera during storage (at 4-6 degrees C) has revealed that immune sera show greater stability during storage under such conditions in comparison with sera obtained from nonimmune animals.
authors.forename: T N
authors.initials: TN
authors.lastname: Filatova
authors.forename: N I
authors.initials: NI
authors.lastname: Churakova
authors.forename: E V
authors.initials: EV
authors.lastname: Titova
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Filippov
authors.forename: Iu P
authors.initials: IuP
authors.lastname: Vartanian
mesh_terms: D000818:Animals; D002138:Calibration; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation / Q000379:methods; D004356:Drug Storage; D007106:Immune Sera / Q000032:analysis*; D005779:Immunodiffusion; D007136:Immunoglobulins / Q000032:analysis; D009345:Neisseria meningitidis / Q000276:immunology*; D011817:Rabbits; D012709:Serum Albumin / Q000032:analysis; D013696:Temperature; D013997:Time Factors
chemical_list: D007106:Immune Sera; D007136:Immunoglobulins; D012709:Serum Albumin
vernacular_title: Izuchenie sostava immunnykh syvorotok protiv Neisseria meningitidis metodom vysokoéffektivnoĭ zhidkostnoĭ khromatografii.