title: High prevalence of tuberculosis in AIDS patients in Spain.
abstract: A total of 67 cases of tuberculosis was diagnosed in the first 100 cases of AIDS, diagnosed according to the former CDC criteria, at a hospital in Madrid, Spain. This is the highest known prevalence of tuberculosis in AIDS patients both within and outside Spain. The clinical manifestations of tuberculosis were very variable and atypical. The rate of isolation of Mycobacterium tuberculosis from blood was particularly high: of 25 patients in whom blood cultures were performed, 16 were positive. In a third of the patients with proven mycobacteremia, blood was the first or the only positive specimen. In general, therapy resulted in rapid clinical improvement, but in some cases mycobacteria were isolated from clinical or necroscopy specimens months after what was considered adequate therapy.
authors.affiliation: Servicio de Microbiología Clínica, Hospital General Gregorio Marañón, Madrid, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Bouza
authors.forename: C
authors.initials: C
authors.lastname: Martín-Scapa
authors.forename: J C
authors.initials: JC
authors.lastname: Bernaldo de Quirós
authors.forename: D
authors.initials: D
authors.lastname: Martínez-Hernández
authors.forename: J
authors.initials: J
authors.lastname: Menarguez
authors.forename: J
authors.initials: J
authors.lastname: Gómez-Rodrigo
authors.forename: J
authors.initials: J
authors.lastname: Cosín
authors.forename: M J
authors.initials: MJ
authors.lastname: Sagues-Cifuentes
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D018805:Sepsis / Q000382:microbiology; D013030:Spain; D014376:Tuberculosis / Q000188:drug therapy / Q000453:epidemiology*