Immunohistochemical localization of neurotensin and beta-endorphin in the rat anterior pituitary gland.
Nakane's enzyme-labeled antibody technique revealed that cells containing neurotensin-like immunoreactivity were widely distributed in the anterior lobe of the pituitary body. Immunohistochemical studies on serial sections showed that a part of neurotensin positive anterior lobe cells contained beta-endorphin-like peptide simultaneously. The results show that beta-endorphin and neurotensin occur together in certain pituitary cells and this is an evidence of coexistence of more than one peptide within one anterior pituitary cell.
Miyoshi
R
R
Kito
S
S
Kishida
T
T
Itoga
E
E
Ogawa
N
N
D000818:Animals; D004723:Endorphins / Q000378:metabolism*; D008297:Male; D009496:Neurotensin / Q000378:metabolism*; D010903:Pituitary Gland, Anterior / Q000166:cytology / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D001615:beta-Endorphin
D004723:Endorphins; D009496:Neurotensin; D001615:beta-Endorphin