Trisomy 4 in a case of acute nonlymphocytic leukemia (M2).
Trisomy 4 in a Japanese patient with type M2 acute nonlymphocytic leukemia is reported. Karyotypic analysis was unsuccessful at diagnosis and complete remission lasted 4 years. The cytogenetic change was detected in the first and second relapses as the only chromosome abnormality. Unusual nuclear irregularities were found in many leukemic cells.
Fujishita
M
M
Department of Medicine, Kochi Medical School, Japan.
Miyagi
T
T
Takeuchi
T
T
Kubonishi
I
I
Niiya
K
K
Taguchi
H
H
Ohtsuki
Y
Y
Miyoshi
I
I
D000208:Acute Disease; D000328:Adult; D002894:Chromosomes, Human, Pair 4; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D007938:Leukemia / Q000235:genetics* / Q000473:pathology; D014314:Trisomy
D005819:Genetic Markers