title: Acute retinal necrosis syndrome presenting with papillitis and arcuate neuroretinitis.
abstract: Acute retinal necrosis (ARN) syndrome is a diffuse uveitis characterized by a peripheral necrotizing retinitis and retinal vasculitis. The authors document and discuss a case of ARN syndrome that initially presented with remarkable changes in the peripapillary retinal nerve fiber layer that they have termed arcuate neuroretinitis. These changes consisted of a well-defined arcuate band of retinitis paralleling the course of a parafoveal nerve fiber bundle. Evaluation of serial serum antibody titers suggests HSV-2 as a possible causative agent in this unique presentation of ARN syndrome.
authors.affiliation: Department of Ophthalmology, University of California, San Francisco.
authors.forename: T
authors.initials: T
authors.lastname: Margolis
authors.forename: A R
authors.initials: AR
authors.lastname: Irvine
authors.forename: W F
authors.initials: WF
authors.lastname: Hoyt
authors.forename: R
authors.initials: R
authors.lastname: Hyman
mesh_terms: D000208:Acute Disease; D003937:Diagnosis, Differential; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D007249:Inflammation; D008875:Middle Aged; D009336:Necrosis; D009443:Neuritis / Q000175:diagnosis*; D010211:Papilledema / Q000175:diagnosis*; D012160:Retina / Q000294:innervation*; D012164:Retinal Diseases / Q000175:diagnosis; D012171:Retinal Vessels; D012173:Retinitis / Q000175:diagnosis*; D013577:Syndrome; D009626:Terminology as Topic; D014605:Uveitis / Q000175:diagnosis*