[Interaction of Neisseria meningitidis with eukaryotic cells in a mixed infection in vitro].
To study the adhesion of meningococci under the conditions of a monoinfection and mixed infection (in association with influenza virus), the experimental model of mixed influenzal and meningococcal infection has been created in the culture of epithelial cells HEp-2. On this model in increase in the intensity of the adhesion of meningococci to eukaryotic cells, as well as in the intensity of the meningococcal colonization of such cells, after their preliminary infection with influenza virus has been observed. The study has revealed that in mixed infection the adsorption of extracellular virions onto the surface of bacteria occurs. During this adsorption viral processes directly interact with the microcapsule of the meningococcus.
Gorokhova
L V
LV
Gosteva
V V
VV
Klitsunova
N V
NV
Mironova
T K
TK
D000327:Adsorption; D001422:Bacterial Adhesion; D002478:Cells, Cultured; D004848:Epithelium / Q000382:microbiology / Q000648:ultrastructure; D006801:Humans; D009980:Influenza A virus / Q000472:pathogenicity / Q000648:ultrastructure; D007251:Influenza, Human / Q000382:microbiology / Q000473:pathology; D008585:Meningitis, Meningococcal / Q000382:microbiology* / Q000473:pathology; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D009345:Neisseria meningitidis / Q000472:pathogenicity* / Q000648:ultrastructure; D014771:Virion / Q000472:pathogenicity / Q000648:ultrastructure
Vzaimodeĭstvie Neisseria menigitidis s éukarioticheskimi kletkami v usloviiakh smeshannoĭ infektsii in vitro.