title: Schistosomiasis mansoni: immunodiagnosis aspects and search for an immunological marker related to therapeutic efficacy.
abstract: The recent findings on immunodiagnosis of schistosomiasis mansoni have shown that purified Schistosoma mansoni antigens do not provide maximum positivity. Therefore, the authors suggest the use of semi-purified antigens for diagnostic purposes. So far, no serological marker for cured patients as shown by negative stool examination was found. However, a tendency of IgG antibody titre decrease was observed, when egg antigen was used.
authors.affiliation: Instituto de Medicina Tropical de São Paulo, Brasil.
authors.forename: H Y
authors.initials: HY
authors.lastname: Kanamura
authors.forename: S
authors.initials: S
authors.lastname: Hoshino-Shimizu
authors.forename: D M
authors.initials: DM
authors.lastname: Lima
authors.forename: C P
authors.initials: CP
authors.lastname: Abrantes
authors.forename: L C
authors.initials: LC
authors.lastname: da Silva
mesh_terms: D000909:Antibodies, Helminth / Q000032:analysis*; D000947:Antigens, Helminth / Q000276:immunology / Q000302:isolation & purification; D015415:Biomarkers / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D005455:Fluorescent Antibody Technique; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D010063:Ovum / Q000276:immunology; D011233:Precipitin Tests; D011237:Predictive Value of Tests; D012555:Schistosomiasis mansoni / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D012556:Schistosomicides / Q000627:therapeutic use
chemical_list: D000909:Antibodies, Helminth; D000947:Antigens, Helminth; D015415:Biomarkers; D007074:Immunoglobulin G; D012556:Schistosomicides