Oral mucosal reactions to cinnamon-flavored chewing gum.
Oral lesions induced by contact with cinnamon flavoring agents are relatively uncommon, and are probably unrecognized as such by many clinicians. Ten patients with these lesions seen during the past 6 years are described in this report. Most patients had a "burning sensation" as their primary symptom. Clinically, lesions appeared as erythematous patches with varying degrees of superimposed keratosis or ulceration, or both. The lesions were usually confined to the buccal mucosa and lateral border of the tongue. The offending agent was almost always cinnamon-flavored chewing gum, and symptoms typically resolved within 1 to 2 days of discontinuing the product containing cinnamon.
Allen
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CM
Diagnostic Services, Ohio State University, College of Dentistry, Columbus 43210.
Blozis
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GG
D000328:Adult; D000368:Aged; D002638:Chewing Gum / Q000009:adverse effects*; D002935:Cinnamomum zeylanicum / Q000009:adverse effects*; D003212:Condiments / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000187:drug effects / Q000473:pathology; D013280:Stomatitis / Q000139:chemically induced* / Q000473:pathology; D014456:Ulcer / Q000139:chemically induced / Q000473:pathology
D002638:Chewing Gum