[The complement system in hepatopathies].
Low serum complement is often observed in cirrhosis of the liver. This is the result of two mechanisms: a failure to synthesise a certain number of components and regulatory proteins of complement, and an increased consumption due to activation of the complement system. This acquired deficit in complement contributes to the increased risk of infection in patients with cirrhosis.
De la Tour
B
B
Kazatchkine
M
M
D000208:Acute Disease; D003167:Complement Activation; D003176:Complement C3 / Q000096:biosynthesis; D003180:Complement C3b Inactivator Proteins / Q000172:deficiency; D017244:Complement Factor I; D003165:Complement System Proteins / Q000096:biosynthesis / Q000172:deficiency / Q000378:metabolism*; D010450:Endopeptidases / Q000172:deficiency; D006525:Hepatitis, Viral, Human / Q000276:immunology; D006801:Humans; D008099:Liver / Q000378:metabolism; D008104:Liver Cirrhosis, Alcoholic / Q000276:immunology; D008107:Liver Diseases / Q000276:immunology*
D003176:Complement C3; D003180:Complement C3b Inactivator Proteins; D003165:Complement System Proteins; D010450:Endopeptidases; D017244:Complement Factor I
Le système du complément au cours des hépatopathies.