Multiple clustered dermatofibromas. Evolution over 20 years.
A 37 year-old man developed, over 20 years, multiple clustered dermatofibromas on the left thigh. Three similar cases have been described previously and the benign course of this lesion has been referred to. Analysis of collagen amino acids revealed a sharp increase of hydroxylysine on the fibrous central zone, suggesting an abnormal accumulation of type IV collagen.
Berbis
P
P
Clinique Dermatologique Hôtel Dieu, Marseille, France.
Benderitter
T
T
Perier
C
C
Frey
J
J
Privat
Y
Y
D000328:Adult; D000596:Amino Acids / Q000032:analysis; D003094:Collagen / Q000032:analysis; D005350:Fibroma / Q000032:analysis / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000032:analysis / Q000473:pathology*; D012878:Skin Neoplasms / Q000032:analysis / Q000473:pathology*
D000596:Amino Acids; D003094:Collagen