Suggestive evidence of genetic linkage between alcoholism and the MNS blood group.
Thirty nuclear families ascertained through an alcoholic proband were studied using segregation and linkage analyses. Linkage was investigated between a putative alcoholism susceptibility (AS) gene and six blood group markers: ABO, Rhesus, Duffy, Kidd, Kell, and MNS. Evidence is presented suggestive of linkage between susceptibility to alcoholism and the MNS blood group.
Hill
S Y
SY
Alcohol and Genetics Research Program, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213.
Aston
C
C
Rabin
B
B
D000017:ABO Blood-Group System / Q000235:genetics; D000437:Alcoholism / Q000235:genetics*; D002878:Chromosomes, Human, Pair 1; D002887:Chromosomes, Human, Pair 18; D002894:Chromosomes, Human, Pair 4; D002899:Chromosomes, Human, Pair 9; D004375:Duffy Blood-Group System / Q000235:genetics; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D007626:Kell Blood-Group System / Q000235:genetics; D007667:Kidd Blood-Group System / Q000235:genetics; D008951:MNSs Blood-Group System / Q000235:genetics*; D008297:Male; D011110:Polymorphism, Genetic; D012204:Rh-Hr Blood-Group System / Q000235:genetics
D000017:ABO Blood-Group System; D004375:Duffy Blood-Group System; D005819:Genetic Markers; D007626:Kell Blood-Group System; D007667:Kidd Blood-Group System; D008951:MNSs Blood-Group System; D012204:Rh-Hr Blood-Group System