[Effect of anti-angina therapy on phospholipid levels of the myocardium in ischemic lesions].
Antianginal treatment of animals with experimentally induced myocardial ischemia produced significant effects on the quantitative and qualitative composition of phospholipids: total phospholipids returned to normal levels, cardiolipins and phosphatidilinosytes were drastically increased. In ischemia, this lipid metabolism derangement appears to be of great significance as it enables the physiochemical status of biological membranes to be relatively stabilized, which is an essential condition for the enzymic system of cardiomyocytes to act.
Dzhanpoladian
E G
EG
Karagezian
K G
KG
Sambelian
V M
VM
Aloian
G A
GA
D000818:Animals; D003327:Coronary Disease / Q000188:drug therapy* / Q000378:metabolism; D004146:Dioxanes / Q000627:therapeutic use; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D005996:Nitroglycerin / Q000627:therapeutic use; D010743:Phospholipids / Q000378:metabolism*; D011433:Propranolol / Q000627:therapeutic use; D011759:Pyrrolidines / Q000627:therapeutic use; D051381:Rats
D004146:Dioxanes; D010743:Phospholipids; D011759:Pyrrolidines; C000661:bumecain; D011433:Propranolol; D005996:Nitroglycerin; C009143:proroxan
Vliianie antianginal'noĭ terapii na soderzhanie fosfolipidov v miokarde pri ishemicheskikh povrezhdeniiakh.