Chromosomal localization of amplified c-myc in a human colon adenocarcinoma cell line with a biotinylated probe.
A c-myc amplified sequence has been localized on a chromosome marker 19q+ with a biotin-labeled probe in the human colon adenocarcinoma SW480 cell line. The advantages of the technique for the localization of amplified DNA sequences are discussed.
Cherif
D
D
Unité INSERM 301 and L.O.I. (CNRS), Hôpital Saint-Louis, Paris, France.
Le Coniat
M
M
Suarez
H G
HG
Bernheim
A
A
Berger
R
R
D000230:Adenocarcinoma / Q000235:genetics*; D001710:Biotin; D002871:Chromosome Banding; D003110:Colonic Neoplasms / Q000235:genetics*; D004247:DNA / Q000235:genetics; D005784:Gene Amplification; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D009693:Nucleic Acid Hybridization; D011519:Proto-Oncogenes; D014407:Tumor Cells, Cultured
D005819:Genetic Markers; D001710:Biotin; D004247:DNA