Reticular-like pigmentary patterns in pseudoxanthoma elasticum.
Of 14 consecutive patients with pseudoxanthoma elasticum (PXE), 9 (64%) had a spectrum of peculiar, sometimes reticular, pigmentary changes in the retina. Ten of 18 (56%) eyes had a random scattering of small, round pigment dots throughout the macula and around the optic nerve, sometimes extending to the equator. In four of 18 (22%) eyes, the pigment clumps appeared in lines, resembling a string of pearls. These strings occasionally radiated from the macula in a spoke-like fashion. In 4 of the 18 (22%) eyes, the pigment clumping occurred in a fishnet, or truly reticular, pattern. Of the 18 eyes in these 9 patients, 12 (67%) had subretinal neovascularization. Of the ten eyes in the five patients who did not show this pigmentary change, two (20%) had subretinal neovascularization.
McDonald
H R
HR
Department of Ophthalmology, University of California, San Francisco.
Schatz
H
H
Aaberg
T M
TM
D000328:Adult; D000368:Aged; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology; D011561:Pseudoxanthoma Elasticum / Q000473:pathology*; D012164:Retinal Diseases / Q000473:pathology*; D012168:Retinal Pigments; D014786:Vision Disorders / Q000209:etiology
D012168:Retinal Pigments