Ventriculomegaly in neurofibromatosis-1. Association with Chiari type I malformation.
Two cases of von Recklinghausen neurofibromatosis with a hitherto unreported association of ventriculomegaly and a Chiari type I malformation are described. Both cases had skeletal abnormalities at the cervicomedullary junction, contributing to neurological symptoms in 1. The literature on nontumor-related ventriculomegaly in neurofibromatosis is reviewed. The Chiari type I malformation should be considered as a cause of nontumoral ventricular enlargement in patients with von Recklinghausen neurofibromatosis.
Afifi
A K
AK
Department of Pediatrics, Division of Child Neurology, University of Iowa, Iowa City.
Dolan
K D
KD
Van Gilder
J C
JC
Fincham
R W
RW
D000328:Adult; D001139:Arnold-Chiari Malformation / Q000150:complications* / Q000175:diagnosis; D001927:Brain Diseases / Q000150:complications* / Q000175:diagnosis; D002552:Cerebral Ventricles / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000150:complications*