title: Pattern descriptors and the unidentified reading frame 6 human mtDNA dinucleotide-binding site.
abstract: In an effort to identify the structural elements essential to a given protein function a new pattern-directed inference system has been developed. It has been employed to identify a potential dinucleotide-binding domain within the human mitochondrial unidentified reading frame 6 product, thereby supporting an earlier study that this gene may encode a NADH dehydrogenase subunit.
authors.affiliation: Dana-Farber Cancer Institute, Harvard School of Public Health, Boston, Massachusetts 02115.
authors.forename: T A
authors.initials: TA
authors.lastname: Webster
authors.forename: R H
authors.initials: RH
authors.lastname: Lathrop
authors.forename: T F
authors.initials: TF
authors.lastname: Smith
mesh_terms: D001665:Binding Sites; D004272:DNA, Mitochondrial / Q000235:genetics; D015226:Dinucleoside Phosphates; D006801:Humans; D009245:NADH Dehydrogenase / Q000235:genetics; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides; D011487:Protein Conformation
chemical_list: D004272:DNA, Mitochondrial; D015226:Dinucleoside Phosphates; D009841:Oligonucleotides; D009245:NADH Dehydrogenase