[Various mechanisms of immune homeostasis in myocardial infarction].
Dynamic alterations and interrelationships of the patterns of humoral immunity (immunoglobulins and immune complexes) were studied in 77 patients with myocardium infarction and in 23 healthy donors. Stimulation of immunity homeostasis in the patients with acute form of myocardium infarction was manifested as an increase in content of immunoglobulins and immune complexes. Content of immunoglobulin G was distinctly decreased in epistenocardic pericarditis. High rate of correlations was found between the patterns studied in healthy persons (r = 0.7 = 0.85). During the acute period of myocardium infarction disbalance of homeostasis was observed, which was expressed as a decrease in the correlation coefficient down to r = 0.41 = 0.54. An increase in the interrelation and redistribution of the argument-functional parameters were detected in dynamics of the disease.
Dobrotina
N A
NA
Kopytova
T V
TV
Berezina
M A
MA
D000328:Adult; D000368:Aged; D000936:Antigen-Antibody Complex / Q000032:analysis*; D001323:Autoantibodies / Q000032:analysis*; D005260:Female; D006706:Homeostasis; D006801:Humans; D005779:Immunodiffusion; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000276:immunology*
D000936:Antigen-Antibody Complex; D001323:Autoantibodies; D007136:Immunoglobulins
Nekotorye mekhanizmy immunnogo gomeostaza pri infarkte miokarda.