title: Serious bacterial cellulitis of the periorbital area in two patients with systemic lupus erythematosus.
abstract: We describe the occurrence of bacterial cellulitis in the periorbital area of 2 patients with systemic lupus erythematosus (SLE). In both patients the antibacterial activity of polymorphonuclear leucocytes was normal. The opsonic capacity of serum was defective in one patient (corresponding to decreased levels of the 4th component of complement) and normal in the other. Seemingly minor bacterial infections of the skin in patients with SLE should warrant aggressive antimicrobial treatment.
authors.affiliation: Department of Internal Medicine (Division of Immunopathology), University Hospital, Utrecht, The Netherlands.
authors.forename: R H
authors.initials: RH
authors.lastname: Derksen
authors.forename: B P
authors.initials: BP
authors.lastname: Overbeek
authors.forename: P H
authors.initials: PH
authors.lastname: Poeschmann
mesh_terms: D000293:Adolescent; D000328:Adult; D001770:Blood Bactericidal Activity; D002481:Cellulitis / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D009504:Neutrophils / Q000502:physiology; D009895:Opsonin Proteins / Q000494:pharmacology; D010587:Phagocytosis; D012698:Serologic Tests; D013203:Staphylococcal Infections; D013290:Streptococcal Infections
chemical_list: D009895:Opsonin Proteins