Prevalence and clinical peculiarities of essential hypertension in a population living at high altitude.
Screening examinations were performed in ethnically related populations of men aged 30-59 years, living in high mountain regions of Tien-Shan and Pamir (2800-3600 m above sea level) and in the lowlands (800-900 m). The incidence of borderline hypertension (BH) and essential hypertension (EH) was statistically significantly higher among the inhabitants of lowland regions: EH was recorded among them in 15.4%, vs. 4.2% among men living at high altitude; BH was present among the male lowland population (LL) in 10.6% vs. 6.0% among highlanders (HL). The main characteristic clinico-functional feature of EH in HL was its frequent association with high-altitude pulmonary hypertension and right ventricular hypertrophy. Aldosterone excretion was in HL with EH substantially lower, and sodium excretion higher, than in a comparable group of lowland inhabitants.
Mirrakhimov
M M
MM
Rafibekova
Zh S
ZhS
Dzhumagulova
A S
AS
Meimanaliev
T S
TS
Murataliev
T M
TM
Shatemirova
K K
KK
D000328:Adult; D000367:Age Factors; D000450:Aldosterone / Q000097:blood; D000472:Alkalosis, Respiratory / Q000209:etiology / Q000378:metabolism; D000531:Altitude; D000532:Altitude Sickness / Q000150:complications / Q000453:epidemiology; D006332:Cardiomegaly / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D006973:Hypertension / Q000453:epidemiology* / Q000378:metabolism; D006976:Hypertension, Pulmonary / Q000453:epidemiology / Q000209:etiology; D007707:Kyrgyzstan; D050356:Lipid Metabolism; D008297:Male; D008875:Middle Aged; D009790:Occupations; D011188:Potassium / Q000032:analysis
D000450:Aldosterone; D011188:Potassium