An endogenous ligand for the central sulfonylurea receptor.
An endogenous ligand for the rat central sulfonylurea receptor has been evidenced in the rat central nervous system. The characteristics of this ligand (extractibility, non-dialysability, chromatographic behaviour on different media, sensitivity to proteases) indicate that it is a neutral to slightly basic peptide.
Virsolvy-Vergine
A
A
Centre CNRS-INSERM de Pharmacologie-Endocrinologie, Montpellier, France.
Brück
M
M
Dufour
M
M
Cauvin
A
A
Lupo
B
B
Bataille
D
D
D018528:ATP-Binding Cassette Transporters; D000818:Animals; D002462:Cell Membrane / Q000032:analysis / Q000378:metabolism; D002540:Cerebral Cortex / Q000032:analysis* / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D002852:Chromatography, Ion Exchange; D005913:Glipizide / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D008297:Male; D008970:Molecular Weight; D010206:Papain / Q000494:pharmacology; D010434:Pepsin A / Q000494:pharmacology; D010455:Peptides / Q000032:analysis* / Q000378:metabolism; D010741:Phospholipases A / Q000494:pharmacology; D015221:Potassium Channels; D024661:Potassium Channels, Inwardly Rectifying; D051381:Rats; D011919:Rats, Inbred Strains; D011955:Receptors, Drug / Q000378:metabolism*; D064233:Sulfonylurea Receptors
D018528:ATP-Binding Cassette Transporters; D010455:Peptides; D015221:Potassium Channels; D024661:Potassium Channels, Inwardly Rectifying; D011955:Receptors, Drug; D064233:Sulfonylurea Receptors; D010741:Phospholipases A; D010206:Papain; D010434:Pepsin A; D005913:Glipizide