Transplantation in Manitoba.
1. Renal transplantation can be performed at small regional centers as successfully as at large centers. 2. Immunosuppression should be individualized for the patient thereby avoiding the use of costly and often clinically complicated immunosuppressive regimens. 3. Small centers need to participate in large regional pools in order to give highly presensitized patients a reasonable chance of successful transplantation. 4. Long-term patient compliance is a major problem and requires careful surveillance of patients' adherence to their prescribed therapy. Frequent follow-up also allows for the detection of late rejection episodes which can often be reversed.
Jeffery
J R
JR
Department of Medicine, University of Manitoba, Winnipeg.
Downs
A
A
Fong
H
H
Hosking
D
D
McKenna
R
R
McKenzie
J K
JK
Ramsey
E
E
Rush
D N
DN
Thomson
A E
AE
Walker
R
R
D006085:Graft Survival; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods; D016030:Kidney Transplantation / Q000401:mortality / Q000706:statistics & numerical data*; D008350:Manitoba / Q000453:epidemiology; D011300:Preoperative Care / Q000379:methods; D016016:Proportional Hazards Models; D012086:Reoperation / Q000706:statistics & numerical data; D012307:Risk Factors; D015996:Survival Rate; D014019:Tissue Donors