Heterochromatic variants and their association with neoplasias: V. Non-Hodgkin's lymphomas.
A study of heterochromatic regions in chromosomes #1, #9, and #16 was performed on lymphocytes of peripheral blood from 55 normal individuals and 50 patients with non-Hodgkin's lymphoma (NHL). Heteromorphism was present in 90% of the NHL patients, compared with 44% in normal individuals (p less than 0.001). An increase of inv(1), 1qh-, and 9qh-variants was observed in malignant lymphoma patients with respect to controls.
Labal de Vinuesa
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Centro Austral de Investigaciones Científicas (CADIC), Tierra del Fuego, Argentina.
Slavutsky
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Mudry de Pargament
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Larripa
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D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002878:Chromosomes, Human, Pair 1; D002885:Chromosomes, Human, Pair 16; D002899:Chromosomes, Human, Pair 9; D005819:Genetic Markers; D006570:Heterochromatin / Q000235:genetics*; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000235:genetics*; D008875:Middle Aged; D011110:Polymorphism, Genetic
D005819:Genetic Markers; D006570:Heterochromatin