[Common migraine. Changes in conjugated and unconjugated catecholamines].
Plasma levels of conjugated and unconjugated catecholamines were measured in 27 migraineurs between attacks, in 9 migraineurs 1 to 2 hours after the onset of an attack, and in 30 controls. There were no significant changes in conjugated catecholamines; in contrast, a significant rise (p less than 0.01; KS test) in unconjugated dopamine, noradrenaline and adrenaline levels was observed during attacks. These results confirm that migrainous attacks are associated with platelet activation and with overactivity of the sympathetic system.
Pradalier
A
A
Launay
J M
JM
Dry
J
J
Dreux
C
C
Artigou
C
C
D000293:Adolescent; D000328:Adult; D002395:Catecholamines / Q000097:blood* / Q000378:metabolism / Q000502:physiology; D004298:Dopamine / Q000097:blood; D004837:Epinephrine / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000097:blood* / Q000378:metabolism; D009638:Norepinephrine / Q000097:blood
D002395:Catecholamines; D004298:Dopamine; D009638:Norepinephrine; D004837:Epinephrine
Migraine commune. Variations des catécholamines conjuguées et non conjuguées.