title: Delayed seroconversion to HIV in a hemophiliac.
abstract: In a 14-year-old boy with severe hemophilia B, HIV seroconversion was observed about 2 years after substitution therapy had been changed to heat-treated PPSB concentrates. This shows that HIV-antibodies may appear in hemophiliacs after time periods longer than generally assumed.
authors.affiliation: Klinische und Molekulare Virologie, Universität Erlangen-Nürnberg.
authors.forename: J
authors.initials: J
authors.lastname: von Hintzenstern
authors.forename: G
authors.initials: G
authors.lastname: Jahn
authors.forename: K
authors.initials: K
authors.lastname: Mang
authors.forename: D
authors.initials: D
authors.lastname: Harms
authors.forename: B
authors.initials: B
authors.lastname: Fleckenstein
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology*; D000293:Adolescent; D000914:Antibodies, Viral / Q000032:analysis*; D005164:Factor IX / Q000627:therapeutic use; D006678:HIV / Q000276:immunology*; D015483:HIV Antibodies; D002836:Hemophilia B / Q000276:immunology* / Q000628:therapy; D006801:Humans; D008297:Male
chemical_list: D000914:Antibodies, Viral; D015483:HIV Antibodies; D005164:Factor IX