title: Perforation of the intestine in inflammatory bowel disease. An OMGE survey.
abstract: This presentation assesses the incidence of perforation of the intestine in patients with inflammatory bowel disease by reviewing the incidence of this complication in a total of 3175 patients from the OMGE inflammatory bowel disease multi-national survey. Amongst 1928 patients with ulcerative colitis, perforation was noted in only 5 (0.3%), which is much lower than in previous series (from 1% to 2%). By contrast, 19 of 1247 patients with Crohn's disease had perforated (1.5%). The survey thus suggests that the incidence of perforation in ulcerative colitis has fallen in the last 2 decades, probably as a result of the widespread implementation of early surgery. The risk of perforation of Crohn's disease remains quite high.
authors.affiliation: Ullevål Hospital, Oslo, Norway.
authors.forename: A
authors.initials: A
authors.lastname: Softley
authors.forename: S E
authors.initials: SE
authors.lastname: Clamp
authors.forename: I A
authors.initials: IA
authors.lastname: Bouchier
authors.forename: J
authors.initials: J
authors.lastname: Myren
authors.forename: G
authors.initials: G
authors.lastname: Watkinson
authors.forename: F T
authors.initials: FT
authors.lastname: de Dombal
mesh_terms: D003093:Colitis, Ulcerative / Q000150:complications*; D003424:Crohn Disease / Q000150:complications*; D006306:Health Surveys; D006801:Humans; D007391:International Cooperation; D007416:Intestinal Perforation / Q000209:etiology*; D008532:Megacolon, Toxic / Q000209:etiology