title: [Serum sickness after fibrinolysis using intravenous streptokinase in myocardial infarction].
abstract: A case of serum sickness was observed 7 days after administration of intravenous streptokinase in the acute phase of myocardial infarction. The clinical presentation was the sudden development of fever, a papuloerythematous skin rash, myalgia and polyarthritis accompanied by a severe biological inflammatory syndrome without any signs of bacterial or viral infection. Spontaneous regression was observed within 72 hours. Although this complication of streptokinase fibrinolysis seems to be rare, clinicians should be aware of it and not confuse the allergic reaction with that of another drug, the withdrawal of which could be prejudicial for the patient.
authors.affiliation: Service de Cardiologie, Hôpital Ambroise-Paré, Boulogne.
authors.forename: F
authors.initials: F
authors.lastname: Albert
authors.forename: O
authors.initials: O
authors.lastname: Dubourg
authors.forename: G
authors.initials: G
authors.lastname: Steg
authors.forename: G
authors.initials: G
authors.lastname: Delorme
authors.forename: J P
authors.initials: JP
authors.lastname: Bourdarias
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D012713:Serum Sickness / Q000139:chemically induced*; D013300:Streptokinase / Q000009:adverse effects*
chemical_list: D013300:Streptokinase
vernacular_title: Maladie sérique après fibrinolyse par streptokinase intraveineuse au cours d'un infarctus du myocarde.