Plasma luteinizing hormone and progesterone concentrations in goats with estrous cycles of normal or short duration after prostaglandin F2 alpha administration during diestrus or pregnancy.
Plasma luteinizing hormone (LH) and progesterone concentrations were compared in does experiencing short-duration estrous cycles and in does with estrous cycles of normal duration. The short-duration estrous cycles were observed immediately after induction of abortion in pregnant does by use of prostaglandin (PG) F2 alpha. Intramuscular administration of 5 mg of PGF2 alpha was accomplished in 8 does that were 52 to 63 days into gestation and in 9 cycling does at 7 to 10 days after estrus. In both groups, the mean plasma concentration of progesterone decreased from a luteal phase concentration immediately before to less than 1 ng/ml by 24 hours after PGF2 alpha administration. Of the 8 does that aborted, 6 experienced short-duration estrous cycles, and 4 of these 6 had an LH surge during the time of blood sample collection. The mean time from PGF2 alpha administration to the LH surge was significantly (P less than 0.05) longer in does with short-duration estrous cycles (71 hours) than that in does with estrous cycles of normal duration (58 hours). The mean area under the LH concentration curve was significantly (P less than 0.005) less for does with short-duration estrous cycles. Short-duration estrous cycles were associated with delayed preovulatory LH surges of reduced magnitude.
Bretzlaff
K N
KN
Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana 61801.
Weston
P G
PG
Hixon
J E
JE
Ott
R S
RS
D000028:Abortion, Induced / Q000662:veterinary; D000034:Abortion, Veterinary / Q000139:chemically induced; D000818:Animals; D004031:Diestrus / Q000187:drug effects; D015237:Dinoprost; D004971:Estrus / Q000097:blood*; D005260:Female; D006041:Goats / Q000097:blood* / Q000502:physiology; D007986:Luteinizing Hormone / Q000097:blood*; D011247:Pregnancy; D011374:Progesterone / Q000097:blood*; D011460:Prostaglandins F / Q000494:pharmacology*
D011460:Prostaglandins F; D011374:Progesterone; D007986:Luteinizing Hormone; D015237:Dinoprost