title: Structure, distribution, and expression of an ancient murine endogenous retroviruslike DNA family.
abstract: An endogenous retroviruslike DNA, B-26, was cloned from a BALB/c mouse embryo gene library by using a generalized murine leukemia virus DNA probe. Southern blot hybridization and nucleotide sequence analyses indicated that B-26 DNA might be a novel member of the GLN DNA family (A. Itin and E. Keshet, J. Virol. 59:301-307, 1986) which contains murine leukemia virus-related pol and env sequences. Northern analysis indicated that B-26-related RNAs of 8.4 and 3.0 kilobases were transcribed in thymus, spleen, brain, and liver tissues of 6-week-old BALB/c mice.
authors.affiliation: Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892.
authors.forename: M M
authors.initials: MM
authors.lastname: Obata
authors.forename: A S
authors.initials: AS
authors.lastname: Khan
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D015342:DNA Probes; D004279:DNA, Viral / Q000096:biosynthesis / Q000302:isolation & purification*; D015151:Immunoblotting; D051379:Mice; D008807:Mice, Inbred BALB C / Q000235:genetics; D008969:Molecular Sequence Data; D008979:Moloney murine leukemia virus / Q000235:genetics; D005810:Multigene Family; D014176:Protein Biosynthesis; D011533:Proviruses / Q000235:genetics; D015183:Restriction Mapping; D012190:Retroviridae / Q000235:genetics*
chemical_list: C057417:DNA B-26; D015342:DNA Probes; D004279:DNA, Viral