[In vitro activity of an extract of Yersinia enterocolitica 0:3 biotype 4 on lymphoblastic transformation].
Effects of an extract from Y. enterocolitica 0:3 biotype 4 on mouse splenocytes and human lymphocytes cultures were examined. Low doses had a mitogenic action on splenocytes, while high doses inhibited tritiated thymidine incorporation into the cells. With human lymphocytes only inhibitory effect was observed.
Binder
P
P
Paucod
J C
JC
Vidal
D
D
Pribat
A
A
Da Costa
J M
JM
Creach
O
O
D000818:Animals; D001426:Bacterial Proteins / Q000276:immunology*; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D006801:Humans; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000166:cytology; D051379:Mice; D008815:Mice, Inbred Strains; D013154:Spleen / Q000166:cytology; D013936:Thymidine / Q000378:metabolism; D014316:Tritium; D015008:Yersinia enterocolitica / Q000276:immunology*
D001426:Bacterial Proteins; D014316:Tritium; D013936:Thymidine
Etude in vitro de l'activité d'un extrait de Yersinia enterocolitica 0:3 biotype 4 sur la transformation lymphoblastique.