title: [Proctomucosectomy and colo-anal anastomosis in rectovaginal fistula following the use of suppositories containing ergotamine].
abstract: We observed a rectovaginal fistula in 2 patients who had applied ergotamine suppositories against migraine headaches. The local effect of ergotamine on the rectum mucosa as well as the higher systemic concentration after rectal application seem to promote the development of a rectovaginal fistula. Different methods for the surgical fistula repair are discussed, depending on location and diameter of the fistula. In our patients we have carried out the abdomino-transanal resection of the rectum with sutured colo-anal anastomosis.
authors.affiliation: Chirurgische Klinik, Katharinenhospital Stuttgart.
authors.forename: A
authors.initials: A
authors.lastname: Schwab
authors.forename: K
authors.initials: K
authors.lastname: Werthmann
authors.forename: P
authors.initials: P
authors.lastname: Merkle
authors.forename: H H
authors.initials: HH
authors.lastname: Thiele
mesh_terms: D000328:Adult; D001003:Anal Canal / Q000601:surgery; D003106:Colon / Q000601:surgery; D003125:Colostomy; D004878:Ergotamine; D004879:Ergotamines / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000601:surgery; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy*; D012006:Rectovaginal Fistula / Q000139:chemically induced* / Q000601:surgery; D012007:Rectum / Q000601:surgery; D013488:Suppositories; D013536:Suture Techniques
chemical_list: D004879:Ergotamines; D013488:Suppositories; D004878:Ergotamine
vernacular_title: Proktomucosektomie und coloanale Anastomose bei recto-vaginaler Fistel nach Anwendung ergotaminhaltiger Suppositorien.