A rare human model for oncogenesis.
A rare female human model of oral carcinoma (OC) who refrained from any type of tobacco and/or betel nut habits, belonged to an younger age group, had no pre-existing precancerous lesions in the oral cavity and who was exposed chronically to cashew nut oil, is presented. The role of genetic inherited influences, occupational and endocrine disturbances with racial factors in the causation of oral carcinoma is discussed. The significance of further studies at the genetic level, to rule out protooncogenic activation in the causation of oral cancer is summed up. The literature on the concept of oncogenesis is reviewed briefly.
Rajendran
R
R
Medical College, Trivandrum, South India.
Anil
S
S
Vijayakumar
T
T
D000293:Adolescent; D002294:Carcinoma, Squamous Cell / Q000209:etiology*; D005260:Female; D006801:Humans; D009754:Nuts / Q000009:adverse effects*; D012307:Risk Factors; D014062:Tongue Neoplasms / Q000209:etiology*