Lack of differential cognitive effects of lithium and carbamazepine in bipolar affective disorder.
Cognitive functioning was assessed in medication-free as well as carbamazepine- and lithium-treated patients with manic-depressive illness. Across a range of tests measuring attention, concentration, visuomotor function, and memory, no significant differences were observed across the three patient groups as compared with control subjects without manic-depressive illness. The clinical and theoretical implications of these findings are discussed.
Joffe
R T
RT
Department of Psychiatry, St. Michael's Hospital, Toronto, Ontario, Canada.
MacDonald
C
C
Kutcher
S P
SP
D000328:Adult; D001288:Attention / Q000187:drug effects; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000523:psychology; D002220:Carbamazepine / Q000627:therapeutic use*; D003071:Cognition / Q000187:drug effects*; D005260:Female; D006801:Humans; D008094:Lithium / Q000627:therapeutic use*; D016651:Lithium Carbonate; D008297:Male; D011939:Mental Recall / Q000187:drug effects; D011597:Psychomotor Performance / Q000187:drug effects
D016651:Lithium Carbonate; D002220:Carbamazepine; D008094:Lithium