title: [Information concerning radiation-induced sarcomas. Report on 2 cases].
abstract: Two cases of radiation-induced sarcomas are presented. Osteosarcomas developed in the frontal bone after a latency period of 36 years following operation for brain tumor with post-operative irradiation (48 Gy) in one patient and in the region of the right sacro-iliac joint after ablation of testis for seminoma with post-operative irradiation (60 Gy) in another patient. In the literature, the risk of developing an irradiation-induced sarcoma is considered to be low (0.05-0.2%). Both cases, however, underline the necessity of an exact indication for irradiation to avoid such complications.
authors.affiliation: Institut für Pathologie, Friedrich-Schiller-Universität Jena.
authors.forename: A
authors.initials: A
authors.lastname: Schmidt
authors.forename: D
authors.initials: D
authors.lastname: Kob
authors.forename: H
authors.initials: H
authors.lastname: Kosmehl
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000473:pathology*; D001932:Brain Neoplasms / Q000532:radiotherapy; D003131:Combined Modality Therapy; D004407:Dysgerminoma / Q000532:radiotherapy; D005624:Frontal Bone / Q000473:pathology* / Q000528:radiation effects; D006801:Humans; D007085:Ilium / Q000473:pathology* / Q000528:radiation effects; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000473:pathology*; D012516:Osteosarcoma / Q000473:pathology*; D012888:Skull Neoplasms / Q000473:pathology*; D013736:Testicular Neoplasms / Q000532:radiotherapy
vernacular_title: Zur Kenntnis strahlenbedingter Sarkome. Mitteilung über 2 Beobachtungen.