title: [The concept of basic therapy of chronic polyarthritis with D-penicillamine: clinical experiences over 10 years].
abstract: Rheumatoid arthritis is a chronic lifelong disease, facts which must be considered when concepts of therapy are developed. This paper reports retrospectively analyzed results of long-term therapy using D-penicillamine. One-hundred-sixteen patients were selected for critical analysis from among 257 treated patients. Judgment was made according to the parameters: inflammation activity, radiological progression, remission rate, clinical outcome-measurement. The results show that the clinical course of the disease is influenced by the treatment and they confirm the need for long-term therapy with an emphasis on immunomodulation.
authors.affiliation: Medizinisches Zentrum, Bad Ragaz.
authors.forename: R
authors.initials: R
authors.lastname: Hohmeister
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000097:blood / Q000000981:diagnostic imaging / Q000188:drug therapy*; D001175:Arthrography; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000378:metabolism; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008134:Long-Term Care; D008297:Male; D008875:Middle Aged; D010396:Penicillamine / Q000009:adverse effects / Q000627:therapeutic use*; D012189:Retrospective Studies
chemical_list: D002097:C-Reactive Protein; D010396:Penicillamine
vernacular_title: Konzept der Basistherapie der chronischen Polyarthritis mit D-Penicillamin: klinische Erfahrungen über 10 Jahre.