Use of the flexible film isolator as a single circuit hypoxic chamber for small animals.
PVC isolators are now widely used for housing animals and provide a readily available pretested air-tight chamber (Pendry, 1984; Trexler, 1984). We have adapted a flexible film isolator for use as a hypoxic chamber for small animals. The environment within the chamber can be easily and continuously monitored with indwelling probes, obviating the need for a separate circuit for gas analysis. This design has been used for long-term studies of chronic hypoxia.
Winter
R J
RJ
Keast
C G
CG
Butler
P R
PR
Rudd
R M
RM
D000818:Animals; D001273:Atmosphere Exposure Chambers; D006332:Cardiomegaly / Q000662:veterinary; D004780:Environment, Controlled; D006976:Hypertension, Pulmonary / Q000662:veterinary; D000860:Hypoxia / Q000503:physiopathology / Q000662:veterinary*; D011086:Polycythemia / Q000662:veterinary; D051381:Rats; D011919:Rats, Inbred Strains; D012376:Rodent Diseases / Q000503:physiopathology*