Contractile activity enhances the synthesis of hexokinase II in rat skeletal muscle.
An 11-fold increase in hexokinase activity and the hexokinase II isoform was found in rat tibialis anterior muscle after 7 days of chronic, low-frequency stimulation. In vivo labeling studies showed that this increase in enzyme protein content was related to an approx. 30-fold increase in [35S] methionine incorporation.
Weber
F E
FE
Fakultät für Biologie, Universität Konstanz, FRG.
Pette
D
D
D000818:Animals; D004558:Electric Stimulation; D006593:Hexokinase / Q000096:biosynthesis*; D007527:Isoenzymes / Q000096:biosynthesis*; D008297:Male; D009119:Muscle Contraction; D009132:Muscles / Q000201:enzymology* / Q000294:innervation / Q000502:physiology; D010525:Peripheral Nerves / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains
D007527:Isoenzymes; D006593:Hexokinase