title: Sleep apnea in olivopontocerebellar degeneration: treatment with trazodone.
abstract: A 37-year-old man with a 19-year history of progressive autosomal-dominant olivopontocerebellar degeneration developed excessive daytime sleepiness and paroxysmal episodes that clinically resembled an ictal or postictal state. Polysomnography showed sleep apnea. Long-term therapy with trazodone resulted in resolution of the paroxysmal episodes, disappearance of daytime sleepiness, and gradual improvement of sleep architecture over several months.
authors.affiliation: Department of Neurology, University of Chicago, IL 60637.
authors.forename: E F
authors.initials: EF
authors.lastname: Salazar-Grueso
authors.forename: R S
authors.initials: RS
authors.lastname: Rosenberg
authors.forename: R P
authors.initials: RP
authors.lastname: Roos
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D009849:Olivopontocerebellar Atrophies / Q000150:complications*; D012891:Sleep Apnea Syndromes / Q000188:drug therapy / Q000209:etiology*; D013132:Spinocerebellar Degenerations / Q000150:complications*; D014196:Trazodone / Q000627:therapeutic use*
chemical_list: D014196:Trazodone