Secretor status, candidal carriage and candidal infection in patients with diabetes mellitus.
One hundred and nine patients with diabetes mellitus and 100 age-, sex- and denture-status-matched, non-diabetic individuals were investigated prospectively. Comparison was made of oral candidal carriage, clinical infection and inherited ability to secrete blood group antigens in saliva. Diabetic patients had a significantly higher prevalence of oral candidal carriage and infection (P less than 0.001) than non-diabetic individuals, but the candidal load between the 2 groups, was not significant. A comparable proportion of insulin-dependent, non-insulin dependent and control groups were secretors of blood group antigens, and there was no difference in the oral candidal carriage and infection rates between secretors and non-secretors.
Lamey
P J
PJ
Department of Oral Medicine and Pathology, Glasgow Dental Hospital and School, Scotland.
Darwaza
A
A
Fisher
B M
BM
Samaranayake
L P
LP
Macfarlane
T W
TW
Frier
B M
BM
D000017:ABO Blood-Group System; D002175:Candida / Q000302:isolation & purification*; D002180:Candidiasis, Oral / Q000150:complications; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000097:blood / Q000382:microbiology; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000150:complications / Q000382:microbiology; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology*; D009066:Mouth, Edentulous / Q000382:microbiology; D012463:Saliva / Q000032:analysis*
D000017:ABO Blood-Group System