title: Application of high-resolution n.m.r. spectroscopy to the elucidation of the structure of the specific capsular polysaccharide of Streptococcus pneumoniae type 7F.
abstract: The specific capsular polysaccharide of Streptococcus pneumoniae type 7F (American type 51) is a high-molecular-weight neutral polymer composed of 2-acetamido-2-deoxy-D-galactose, 2-acetamido-2-deoxy-D-glucose, D-glucose, D-galactose, L-rhamnose, and 2-O-acetyl-L-rhamnose residues. N.m.r. spectroscopy (1H and 13C), in conjunction with composition and methylation analyses, and periodate oxidation data, showed the polysaccharide to be a branched polymer with a repeating heptasaccharide unit having the following structure. (formula; see text)
authors.affiliation: Division of Biological Sciences, National Research Council of Canada, Ottawa.
authors.forename: M
authors.initials: M
authors.lastname: Moreau
authors.forename: J C
authors.initials: JC
authors.lastname: Richards
authors.forename: M B
authors.initials: MB
authors.lastname: Perry
authors.forename: P J
authors.initials: PJ
authors.lastname: Kniskern
mesh_terms: D000107:Acetylation; D002849:Chromatography, Gas; D002850:Chromatography, Gel; D002852:Chromatography, Ion Exchange; D002855:Chromatography, Thin Layer; D003641:Deamination; D005779:Immunodiffusion; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D011135:Polysaccharides, Bacterial / Q000032:analysis*; D013296:Streptococcus pneumoniae / Q000032:analysis*
chemical_list: D011135:Polysaccharides, Bacterial