Hyaline cartilage-origin bone and soft-tissue neoplasms: MR appearance and histologic correlation.
Magnetic resonance (MR) images and histologic studies of 16 chondroid-matrix lesions were reviewed to determine if any distinctive morphologic or signal features might be discerned. Ten biopsy-proved nonchondroid bone lesions were compared in terms of configuration and signal characteristics. The tumor matrix had a distinctive appearance of homogeneous high signal intensity in a defined lobular configuration on images of all hyaline cartilage lesions obtained with a long repetition time and a long echo time. The areas of hyperintensity relative to muscle corresponded to areas of hyaline cartilage matrix with its uniform composition, low cellularity, and high water content; the lobular morphologic characteristic had an identical histologic correlate. The chondroblastomas, clear-cell chondrosarcoma, and synovial chondromatosis demonstrated a much more cellular stroma, with only scattered islands of chondroid matrix, and were isointense or hypointense compared with muscle on all MR sequences. The distinctive lobular, high-intensity MR appearance was not seen in the ten nonchondroid bone lesions.
Cohen
E K
EK
Department of Radiology, David W. Devon Medical Imaging Center, Philadelphia, PA.
Kressel
H Y
HY
Frank
T S
TS
Fallon
M
M
Burk
D L
DL
Dalinka
M K
MK
Schiebler
M L
ML
D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000175:diagnosis / Q000473:pathology*; D002648:Child; D002812:Chondroma / Q000175:diagnosis / Q000473:pathology*; D002813:Chondrosarcoma / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D012516:Osteosarcoma / Q000175:diagnosis / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000473:pathology*