Enzyme specialization during the evolution of amino acid biosynthetic pathways.
Amino acid sequence similarities detected between enzymes involved in methionine and cysteine biosynthesis, and between enzymes involved in the threonine, isoleucine and tryptophan biosynthetic pathways allow an experimental investigation of the mechanisms whereby metabolic pathways have evolved.
Parsot
C
C
Département de Biochimie et Génétique Moléculaire, Institut Pasteur, Paris, France.
Saint-Girons
I
I
Cohen
G N
GN
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000096:biosynthesis* / Q000235:genetics; D005075:Biological Evolution; D004798:Enzymes / Q000235:genetics / Q000378:metabolism; D008969:Molecular Sequence Data; D012689:Sequence Homology, Nucleic Acid
D000596:Amino Acids; D004798:Enzymes