[Heart and heart-lung transplantation in the child. Indications, methods and results].
Over a 20 month period, 19 children aged 13 days to 15 years (10 under 3 years), received a heart transplantation (isolated: 16 cases, heart-lungs: 3 cases). There were 5 early deaths and 2 during the 3rd postoperative month (total: 44%). Postoperative period is currently over for 8 of the 9 survivors, who lead a normal life, with rather simple constraints: oral cyclosporin-azathioprine immunosuppressive therapy, monthly evaluation in the out-patient department. The method is relatively simple when it concerns heart transplantation. It is quite heavier and complex when it concerns heart-lung transplantation. On the whole, subject to a rigorous selection of the transplant (whose later dysfunction was the major cause of failure, with bacterial or viral infections), these methods find reasonable indications in a number of heart and/or lung malformations or dysfunctions inaccessible to conventional treatments or which used up their resources, making short-term death likely.
Kachaner
J
J
Service de Cardiologie Pédiatrique, Groupe Hospitalier Necker/Enfants-Malades/Laënnec, Paris.
Le Bidois
J
J
Sidi
D
D
Vouhe
P
P
Neveux
J Y
JY
Touati
G
G
D000293:Adolescent; D009202:Cardiomyopathies / Q000601:surgery; D002318:Cardiovascular Diseases / Q000150:complications / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D006330:Heart Defects, Congenital / Q000601:surgery; D016027:Heart Transplantation; D016041:Heart-Lung Transplantation; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications; D007223:Infant; D007231:Infant, Newborn; D008171:Lung Diseases / Q000601:surgery; D016040:Lung Transplantation; D008722:Methods; D011182:Postoperative Care; D014019:Tissue Donors
Transplantations cardique et cardiopulmonaire chez l'enfant. Indications, méthodes et résultats.