Range of toxicity of topical cysteamine in rabbit eyes.
Cysteamine eye drops in concentrations from 0.1% to 10% were tested in albino rabbits in both short and long-term experiments. Toxicity, consisting of an inflammatory response, was proportional to the cysteamine concentration and absent at concentrations at or below 0.5%.
Jain
S
S
Clinical Branch, National Eye Institute, Bethesda, Maryland.
Kuwabara
T
T
Gahl
W A
WA
Kaiser-Kupfer
M I
MI
D000818:Animals; D003543:Cysteamine / Q000008:administration & dosage / Q000633:toxicity*; D005123:Eye / Q000187:drug effects*; D005260:Female; D008297:Male; D009883:Ophthalmic Solutions; D011817:Rabbits
D009883:Ophthalmic Solutions; D003543:Cysteamine