Prenatal diagnosis of tetrasomy 21.
Amniocentesis and prenatal diagnosis were done for late maternal age and an abnormality consistent with Tetrasomy 21 (47,XX, + t(21;21] was found in every cell examined of the initial amniotic fluid. Clinical examination revealed a fetus with many of the signs of Down Syndrome and pathological examination revealed gross abnormalities of the internal structures. Follow-up tissues showed mosaic Tetrasomy 21.
Lopes
V
V
Mak
E
E
Wyatt
P R
PR
D000328:Adult; D000649:Amniocentesis; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D025063:Chromosome Disorders; D002904:Chromosomes, Human, 21-22 and Y; D004314:Down Syndrome / Q000175:diagnosis / Q000235:genetics; D005260:Female; D005333:Fetus / Q000473:pathology; D006801:Humans; D007621:Karyotyping; D009030:Mosaicism; D011247:Pregnancy