[Bactericidal activity examination (MBC) of glutaric aldehyde on anaerobic non-sporing bacteria].
Sensibility (MBC) of 97 strains of non-sporing anaerobes separated from clinical materials coming from oral cavity to glutaric aldehyde (Koch Light Lab) has been examined. The experiments have been carried out by the suspension method adapting it properly to the examinations of anaerobes. 72 hours' cultures in enriched thioglycolate broth containing 10(9) of living cells of anaerobes in 1 ml have been used as inoculum. MBC results were read off after 7 days' incubation at temperature of 37 degrees C. From the total number of 97 strain 7 (7%) strains were sensible to the concentration of 156 to 311 micrograms/ml. In MBC ranges equal to 312 to 624 micrograms/ml 17 (17%) strains perished. Most of the strains namely 51 (53%) strains were damaged by the concentrations of 625 to 1249 micrograms/ml. The remaining 22 (23%) strains exacted to utilize glutaric aldehyde of the concentrations within the range of 1250 to 2500 micrograms/ml. It has been noticed that the strains from Leptotrichia buccalis species were the most sensitive ones. In the remaining of anaerobes under examinations the MBC values were similar to each other.
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D000447:Aldehydes / Q000494:pharmacology*; D001421:Bacteria, Anaerobic / Q000187:drug effects*; D005976:Glutaral / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D009055:Mouth / Q000382:microbiology
D000447:Aldehydes; D005976:Glutaral
Badanie działania bakteriobójczego (MBC) aldehydu glutarowego na nieprzetrwalnikujace bakterie beztlenowe.