Hereford cattle immunized and protected against Boophilus microplus with soluble and membrane-associated antigens from the midgut of ticks.
Hereford cattle were immunized with membranes and soluble components extracted from the midgut of Boophilus microplus. Membrane vaccines protected cattle (91%) against challenge with 3 x 20,000 larval ticks administered at intervals of 7 days. Vaccines made from soluble antigens did not protect cattle. Antibody levels measured by enzyme-linked immunosorbent assay (ELISA) related to the levels of protection induced by vaccination.
Opdebeeck
J P
JP
Department of Parasitology, University of Queensland, St Lucia, Brisbane, Australia.
Wong
J Y
JY
Jackson
L A
LA
Dobson
C
C
D000818:Animals; D000917:Antibody Formation; D000941:Antigens / Q000276:immunology*; D002417:Cattle; D002418:Cattle Diseases / Q000517:prevention & control*; D008297:Male; D013984:Tick Infestations / Q000517:prevention & control / Q000662:veterinary*; D013987:Ticks / Q000276:immunology*; D014611:Vaccination / Q000662:veterinary*
D000941:Antigens