[Detection of antibodies to Neisseria gonorrhoeae in cervicovaginal secretion and in serum].
In 33 female patients suffering from gonorrhoea, we searched for specific antibodies (IgA, IgG, IgM) directed against gonococci by means of the indirect immunofluorescence technique. This investigation was performed both before and after specific treatment. In comparison to 17 healthy women, we found increased rates of IgA and IgG antibodies in the secretion of our patients, the IgA rate being slightly higher than the IgG count; IgM was not detectable at all. In the serum, IgG antibodies clearly dominated over IgA and IgM. After successful treatment, IgA antibodies showed a more rapid reduction than IgG in both secretion and serum.
Koch
H J
HJ
Klinik und Poliklinik für Hautkrankheiten des Bereich Medizin, Friedrich-Schiller-Universität Jena.
Meyer
J
J
D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis*; D002582:Cervix Mucus / Q000276:immunology*; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D009344:Neisseria gonorrhoeae / Q000276:immunology*; D013587:Syphilis / Q000276:immunology*
D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M
Nachweis von Antikörpern gegen Neisseria gonorrhoeae im Zervikovaginalsekret und im Serum.