Canine pancreaticoduodenal autotransplantation: a preparation for human pancreatic transplantation.
This canine pancreaticodunodenal autotransplantation model includes virtually the entire pancreas attached to a duodenal cuff (second portion). The blood supply is based on the superior pancreaticoduodenal artery and the venous outflow on the gastroduodenal vein. The vascular anastomoses are end-to-side to the external iliac artery and vein. Exocrine drainage is channeled through the bladder from the transplanted duodenum. This technique closely resembles whole-organ pancreas transplant in humans with a cystoduodenostomy. The bowel reconstruction consists of a Billroth I gastroduodenostomy and a cholecystoduodenostomy. The entire procedure is relatively free of major complications and may be performed in less than 4 hours.
Miller
A R
AR
Department of Surgery, Mayo Clinic and Foundation, Rochester, Minnesota 55905.
Marsh
C L
CL
Perkins
J D
JD
D000818:Animals; D004285:Dogs; D004386:Duodenum / Q000033:anatomy & histology / Q000637:transplantation*; D005260:Female; D006801:Humans; D008954:Models, Biological; D016035:Pancreas Transplantation / Q000379:methods* / Q000473:pathology; D014182:Transplantation, Autologous