[Specific meningeal involvement in multiple myeloma].
Meningeal involvement is extremely rare in multiple myeloma. Its characteristic features can be derived from the 3 cases presented here and from the 11 cases previously published. Specific signs of meningeal myelomatosis include convulsions, confusion, cranial nerve palsies and plasma cells in the cerebrospinal fluid. Meningitis develops in patients with high tumoral mass myeloma, leukaemic in one-half of the cases. Treatment is ineffective, and death occurs within a few months.
Korinek
A
A
Solal-Celigny
P
P
Kuentz
M
M
Farcet
J P
JP
Clauvel
J P
JP
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000134:cerebrospinal fluid / Q000556:secondary / Q000628:therapy; D008581:Meningitis / Q000134:cerebrospinal fluid / Q000209:etiology*; D008875:Middle Aged; D009101:Multiple Myeloma / Q000134:cerebrospinal fluid / Q000150:complications* / Q000628:therapy; D009422:Nervous System Diseases / Q000209:etiology; D010954:Plasmacytoma / Q000134:cerebrospinal fluid; D011379:Prognosis
Atteinte méningée spécifique au cours du myélome multiple.