[Reduced frequency of homologous recombination in Bacillus subtilis mutants resistant to novobiocin].
B. subtilis mutants resistant to novobiocin that were selected after treatment of the strain SB25 by nitrosoguanidine acquired the slow growth, increased UV-sensitivity, the low frequency of homologous recombination in transduction and transformation. The mutant strains are characterized by the low activity of the double stranded DNA-dependent ATP-ase peculiar for cells with impaired B-subunit of DNA-gyrase.
Barabanshchikov
B I
BI
Malkov
S V
SV
Belov
I S
IS
Khabibullina
G N
GN
D001412:Bacillus subtilis / Q000187:drug effects / Q000235:genetics* / Q000528:radiation effects; D004352:Drug Resistance, Microbial; D005798:Genes, Bacterial; D009154:Mutation; D009675:Novobiocin / Q000494:pharmacology*; D011995:Recombination, Genetic; D014169:Transformation, Bacterial; D014466:Ultraviolet Rays
D009675:Novobiocin
Snizhenie chastoty gomologichnoĭ rekombinatsii u mutantov Bacillus subtilis, ustoĭchivykh k novobiotsinu.