Penicillamine-induced pemphigus foliaceus-like dermatosis. A case with unusual features, successfully treated by plasmapheresis.
A case of a severe, widespread bullous dermatosis clinically resembling pemphigus foliaceus occurred during treatment with penicillamine hydrochloride in a patient with rheumatoid arthritis. Histologically, the disease showed changes compatible with pemphigus vulgaris as well as with a bullous drug eruption. Treatment by plasmapheresis proved to be effective in controlling the disease.
Bahmer
F A
FA
Bambauer
R
R
Stenger
D
D
D003873:Dermatitis, Exfoliative / Q000473:pathology; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010392:Pemphigus / Q000139:chemically induced* / Q000473:pathology / Q000628:therapy; D010396:Penicillamine / Q000009:adverse effects*; D010956:Plasmapheresis; D012867:Skin / Q000473:pathology
D010396:Penicillamine