Reinnervation of sweat glands in the rat hind paw following peripheral nerve injury.
Electrophysiological experiments have been carried out to investigate the time course and extent of sweat gland reinnervation in the rat hind paw. The first evidence of functional reinnervation after nerve transection was obtained at 12 weeks, when the extent of innervation was 20% of that measured in control animals. By 20 weeks, reinnervation had reached almost 50% of control values but then there was no further improvement up to 52 weeks. These results are comparable to those for skin reinnervation by polymodal nociceptor afferents.
Bharali
L A
LA
Department of Physiology, Medical School, Bristol, U.K.
Burgess
S A
SA
Lisney
S J
SJ
Pearson
D
D
D000818:Animals; D005528:Foot; D008297:Male; D009409:Nerve Crush; D009416:Nerve Regeneration; D010525:Peripheral Nerves / Q000502:physiology*; D051381:Rats; D013545:Sweat Glands / Q000294:innervation*; D013546:Sweating