title: Steroids excreted by human skin. II. C19-steroid sulphates in human axillary sweat.
abstract: Beside dehydroepiandrosterone sulphate and androsterone sulphate, 5-androstene-3 beta, 17 beta-diol-3-sulphate and testosterone sulphate were isolated and identified from the axillary sweat of sexually mature women and men. The quantities of these four C19-steroid sulphates were determined individually in the sweat of eight healthy, sexually mature women and men: dehydroepiandrosterone sulphate was found in the highest amount, it was followed by 5-androstene-3 beta, 17 beta-diol-3-sulphate and androsterone sulphate. Testosterone sulphate occurred in the lowest quantity, its excretion amounting to about one-thousandth of that of dehydroepiandrosterone sulphate. Study of the C19-steroid sulphates excreted by the apocrine sweat glands permitted an insight into the steroid metabolism in human skin, which presumably is, closely connected with the steroid hormones of peripheral blood.
authors.forename: I
authors.initials: I
authors.lastname: Tóth
authors.forename: I
authors.initials: I
authors.lastname: Faredin
mesh_terms: D000293:Adolescent; D000328:Adult; D015114:Androstenediol / Q000031:analogs & derivatives / Q000032:analysis*; D000734:Androstenediols / Q000032:analysis*; D000738:Androsterone / Q000031:analogs & derivatives* / Q000032:analysis; D001365:Axilla; D003687:Dehydroepiandrosterone / Q000031:analogs & derivatives* / Q000032:analysis; D019314:Dehydroepiandrosterone Sulfate; D005260:Female; D006801:Humans; D008297:Male; D012737:Sex Factors; D013542:Sweat / Q000032:analysis*; D013739:Testosterone / Q000031:analogs & derivatives* / Q000032:analysis
chemical_list: D000734:Androstenediols; D013739:Testosterone; D003687:Dehydroepiandrosterone; D019314:Dehydroepiandrosterone Sulfate; C033537:5-androstene-3 beta,17 beta-diol sulfate; C028627:testosterone-17-sulfate; D015114:Androstenediol; D000738:Androsterone; C026905:androsterone sulfate