title: Auxotrophic heterozygosities and the ploidy of Candida parapsilosis and Candida krusei.
abstract: Evidence is presented that the type strain of Candida parapsilosis, ATCC 22019, is heterozygous MET/met and that Candida krusei Y 10930 is heterozygous URA/ura. This URA gene determines orotidine-5'-phosphate decarboxylase activity. Because each of these strains is demonstrably disomic for at least one chromosome, they are not haploid but must be diploid or aneuploid.
authors.affiliation: Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892.
authors.forename: W L
authors.initials: WL
authors.lastname: Whelan
authors.forename: K J
authors.initials: KJ
authors.lastname: Kwon-Chung
mesh_terms: D002175:Candida / Q000235:genetics* / Q000378:metabolism; D003470:Culture Media; D005800:Genes, Fungal; D005819:Genetic Markers; D006579:Heterozygote; D009963:Orotic Acid / Q000378:metabolism; D009964:Orotidine-5'-Phosphate Decarboxylase / Q000235:genetics; D011003:Ploidies; D014466:Ultraviolet Rays
chemical_list: D003470:Culture Media; D005819:Genetic Markers; D009963:Orotic Acid; D009964:Orotidine-5'-Phosphate Decarboxylase