title: [Reproducibility of the exercise test and coronary vasomotor tonus].
abstract: The effect of coronary vasomotor tone on exercise test reproducibility was evaluated in two groups of patients. All had an apparently stable angina, a positive first exercise test and at least one significant stenosis at coronary arteriography. Group A patients (n = 30) had a positive ergonovine test (dynamic stenosis) whereas this test was negative (fixed stenosis) in group B patients (n = 29). Patients of both groups underwent two exercise tests without treatment, each of these tests being performed on a different day of the same week, at the same time and according to Bruce's procedure. The reproducibility of angina was poor in group A patients: 6/15 (40 p. 100) as against 18/20 (90 p. 100) in group B patients (p less than 0.05). Moreover, the initially positive exercise test subsequently become negative in 6 of the group A patients and in none of the group B patients (p less than 0.05). The time elapsed before ischaemia appeared was globally increased to the same extent in both groups, but individual variations were more pronounced in group A: a more than 1 minute variation was noted in 63 p. 100 of group A patients and in 18 p. 100 of group B patients (p less than 0.01). Similarly, the double product of ischaemia (-1 mm) varied by more than 20 p. 100 in 37 p. 100 of group A patients and in 14 p. 100 of group B patients. In contrast, the maximum stress parameters were increased to the same degree in both groups, including the double product duration.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Service de cardiologie B et hémodynamique, hôpital cardiologique, CHR de Lille.
authors.forename: G
authors.initials: G
authors.lastname: Traisnel
authors.forename: J M
authors.initials: JM
authors.lastname: Lablanche
authors.forename: J L
authors.initials: JL
authors.lastname: Fourrier
authors.forename: A
authors.initials: A
authors.lastname: Marquand
authors.forename: M E
authors.initials: ME
authors.lastname: Bertrand
mesh_terms: D000787:Angina Pectoris / Q000503:physiopathology*; D017023:Coronary Angiography; D003327:Coronary Disease / Q000188:drug therapy; D003329:Coronary Vasospasm / Q000503:physiopathology*; D004562:Electrocardiography; D004874:Ergonovine; D005080:Exercise Test; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D014666:Vasomotor System / Q000503:physiopathology
chemical_list: D004874:Ergonovine
vernacular_title: Reproductibilité de l'épreuve d'effort et tonus vasomoteur coronaire.