Ofloxacin, a new quinolone for the treatment of gonorrhea.
Forty-three patients with uncomplicated gonorrhea were treated with 400 mg of ofloxacin. All had cultures negative for Neisseria gonorrhoeae at follow-up within two weeks of treatment. Minimal side effects were reported. Ofloxacin appears to be satisfactory as a single-dose oral drug for the treatment of gonococcal urethritis, including those cases caused by penicillinase-producing strains of N. gonorrhoeae.
Rajakumar
M K
MK
Department of Medical Microbiology, University Hospital, Kuala Lumpur, Malaysia.
Ngeow
Y F
YF
Khor
B S
BS
Lim
K F
KF
D000284:Administration, Oral; D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015242:Ofloxacin; D010078:Oxazines / Q000008:administration & dosage / Q000627:therapeutic use*
D000890:Anti-Infective Agents; D010078:Oxazines; D015242:Ofloxacin