title: Molecular studies of the atrial natriuretic factor gene.
abstract: The molecular biology of human atrial natriuretic factor was studied. A cloned rat cDNA probe was used to analyze tissue for the synthesis of atrial natriuretic factor, and the human gene was identified and sequenced. Nucleotide sequence comparison of human and rodent atrial natriuretic factor genes suggests regions that are critical for regulated expression of this cardiac hormone.
authors.forename: C E
authors.initials: CE
authors.lastname: Seidman
authors.forename: K D
authors.initials: KD
authors.lastname: Bloch
authors.forename: J
authors.initials: J
authors.lastname: Zisfein
authors.forename: J A
authors.initials: JA
authors.lastname: Smith
authors.forename: E
authors.initials: E
authors.lastname: Haber
authors.forename: C
authors.initials: C
authors.lastname: Homcy
authors.forename: A D
authors.initials: AD
authors.lastname: Duby
authors.forename: E
authors.initials: E
authors.lastname: Choi
authors.forename: R M
authors.initials: RM
authors.lastname: Graham
authors.forename: J G
authors.initials: JG
authors.lastname: Seidman
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D009320:Atrial Natriuretic Factor; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics; D006801:Humans; D051379:Mice; D008968:Molecular Conformation; D009124:Muscle Proteins / Q000096:biosynthesis / Q000235:genetics*; D009711:Nucleotides / Q000032:analysis; D012333:RNA, Messenger / Q000235:genetics
chemical_list: D009124:Muscle Proteins; D009711:Nucleotides; D012333:RNA, Messenger; D009320:Atrial Natriuretic Factor; D004247:DNA