title: Preoperative serum CA-125 levels in patients with surgical stage I invasive ovarian adenocarcinoma.
abstract: Preoperative serum CA-125 levels were elevated in only three of 13 patients (23%) with a pelvic mass who were found to have surgical stage I invasive ovarian adenocarcinoma. This low incidence is surprising, since elevated levels have been found in greater than 80% of patients with advanced ovarian cancer. This suggests serious limitations for using serum CA-125 levels as a screening test for ovarian cancer.
authors.affiliation: Department of Obstetrics and Gynecology, State University of New York, School of Medicine, Stony Brook 11794-8091.
authors.forename: W J
authors.initials: WJ
authors.lastname: Mann
authors.forename: B
authors.initials: B
authors.lastname: Patsner
authors.forename: H
authors.initials: H
authors.lastname: Cohen
authors.forename: M
authors.initials: M
authors.lastname: Loesch
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000951:Antigens, Neoplasm / Q000032:analysis*; D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor / Q000032:analysis*; D005260:Female; D006801:Humans; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery
chemical_list: D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor