title: Mutations for the autosomal recessive and autosomal dominant forms of polycystic kidney disease are not allelic.
abstract: The autosomal dominant form of polycystic kidney disease (ADPKD) has been linked to the alpha-globin gene locus on 16p. Linkage studies between the autosomal recessive type (ARPKD) and the 3' HVR of the alpha-globin gene cluster showed that the ARPKD and ADPKD are not allelic.
authors.affiliation: Department of Human Genetics, School of Pathology, South African Institute for Medical Research, Johannesburg.
authors.forename: M
authors.initials: M
authors.lastname: Ramsay
authors.forename: S T
authors.initials: ST
authors.lastname: Reeders
authors.forename: P D
authors.initials: PD
authors.lastname: Thomson
authors.forename: L S
authors.initials: LS
authors.lastname: Milner
authors.forename: L
authors.initials: L
authors.lastname: Lazarou
authors.forename: T M
authors.initials: TM
authors.lastname: Barratt
authors.forename: A
authors.initials: A
authors.lastname: Yau
authors.forename: O J
authors.initials: OJ
authors.lastname: Lehmann
authors.forename: T
authors.initials: T
authors.lastname: Jenkins
mesh_terms: D000483:Alleles; D005799:Genes, Dominant; D005808:Genes, Recessive; D008040:Genetic Linkage; D005819:Genetic Markers; D005914:Globins / Q000235:genetics; D006801:Humans; D009154:Mutation; D007690:Polycystic Kidney Diseases / Q000235:genetics*
chemical_list: D005819:Genetic Markers; D005914:Globins