title: Canine pancreaticoduodenal autotransplantation: a preparation for human pancreatic transplantation.
abstract: This canine pancreaticodunodenal autotransplantation model includes virtually the entire pancreas attached to a duodenal cuff (second portion). The blood supply is based on the superior pancreaticoduodenal artery and the venous outflow on the gastroduodenal vein. The vascular anastomoses are end-to-side to the external iliac artery and vein. Exocrine drainage is channeled through the bladder from the transplanted duodenum. This technique closely resembles whole-organ pancreas transplant in humans with a cystoduodenostomy. The bowel reconstruction consists of a Billroth I gastroduodenostomy and a cholecystoduodenostomy. The entire procedure is relatively free of major complications and may be performed in less than 4 hours.
authors.affiliation: Department of Surgery, Mayo Clinic and Foundation, Rochester, Minnesota 55905.
authors.forename: A R
authors.initials: AR
authors.lastname: Miller
authors.forename: C L
authors.initials: CL
authors.lastname: Marsh
authors.forename: J D
authors.initials: JD
authors.lastname: Perkins
mesh_terms: D000818:Animals; D004285:Dogs; D004386:Duodenum / Q000033:anatomy & histology / Q000637:transplantation*; D005260:Female; D006801:Humans; D008954:Models, Biological; D016035:Pancreas Transplantation / Q000379:methods* / Q000473:pathology; D014182:Transplantation, Autologous