Cutaneous angiomas in POEMS syndrome.
POEMS syndrome is an unusual plasma cell dyscrasia with multisystemic manifestations featuring polyneuropathy, organomegaly, endocrinopathy, M protein and constant skin involvement. We have seen a 58-year-old white man presenting with generalized eruptive angiomas as a rare skin manifestation of this syndrome. We review the literature and discuss the pathogenesis of vascular proliferation in this unusual entity.
Puig
L
L
Moreno
A
A
Domingo
P
P
Llistosella
E
E
de Moragas
J M
JM
D006332:Cardiomegaly / Q000150:complications*; D004700:Endocrine System Diseases / Q000150:complications*; D006023:Glycoproteins / Q000096:biosynthesis*; D006391:Hemangioma / Q000209:etiology*; D006529:Hepatomegaly / Q000150:complications*; D006801:Humans; D007674:Kidney Diseases / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000150:complications*; D010265:Paraproteinemias / Q000150:complications; D012871:Skin Diseases / Q000150:complications*; D012878:Skin Neoplasms / Q000209:etiology*; D013577:Syndrome
D006023:Glycoproteins; C023587:protein M (glycoprotein)