title: Comparison of 51Cr-EDTA and 99mTc-DTPA slope clearances in children with vesicoureteric reflux.
abstract: The plasma clearances of 51Cr-EDTA and 99mTc-DTPA have been compared in a series of 154 children with reflux nephropathy. The study has shown that DTPA can replace EDTA with the advantage that it can also be used for dynamic renal imaging and calculation of individual kidney function. However, the source of the DTPA is important, as it has been shown to affect the comparison with EDTA clearance.
authors.affiliation: Department of Clinical Chemistry, Children's Hospital, Birmingham, UK.
authors.forename: P D
authors.initials: PD
authors.lastname: Griffiths
authors.forename: Z
authors.initials: Z
authors.lastname: Drolc
authors.forename: A
authors.initials: A
authors.lastname: Green
authors.forename: C M
authors.initials: CM
authors.lastname: Taylor
authors.forename: R H
authors.initials: RH
authors.lastname: White
mesh_terms: D002648:Child; D002860:Chromium Radioisotopes; D004492:Edetic Acid; D005919:Glomerular Filtration Rate; D006801:Humans; D015609:Organotechnetium Compounds; D004369:Pentetic Acid; D011866:Radioisotope Renography; D016284:Technetium Tc 99m Pentetate; D014718:Vesico-Ureteral Reflux / Q000000981:diagnostic imaging*
chemical_list: D002860:Chromium Radioisotopes; D015609:Organotechnetium Compounds; D004369:Pentetic Acid; D004492:Edetic Acid; D016284:Technetium Tc 99m Pentetate