title: Range of toxicity of topical cysteamine in rabbit eyes.
abstract: Cysteamine eye drops in concentrations from 0.1% to 10% were tested in albino rabbits in both short and long-term experiments. Toxicity, consisting of an inflammatory response, was proportional to the cysteamine concentration and absent at concentrations at or below 0.5%.
authors.affiliation: Clinical Branch, National Eye Institute, Bethesda, Maryland.
authors.forename: S
authors.initials: S
authors.lastname: Jain
authors.forename: T
authors.initials: T
authors.lastname: Kuwabara
authors.forename: W A
authors.initials: WA
authors.lastname: Gahl
authors.forename: M I
authors.initials: MI
authors.lastname: Kaiser-Kupfer
mesh_terms: D000818:Animals; D003543:Cysteamine / Q000008:administration & dosage / Q000633:toxicity*; D005123:Eye / Q000187:drug effects*; D005260:Female; D008297:Male; D009883:Ophthalmic Solutions; D011817:Rabbits
chemical_list: D009883:Ophthalmic Solutions; D003543:Cysteamine