title: Detection of HIV-1 neutralizing antibodies by a simple, rapid, colorimetric assay.
abstract: A rapid, simple, reproducible and semi-quantitative assay to measure neutralizing antibodies has been developed. It employs a unique cell line which is exquisitively sensitive to infection with all HIV isolates tested. The assay is amenable to microtiter formulation as well as analysis by automation.
authors.affiliation: Duke University Medical Center, Department of Surgery, Durham, NC 27710.
authors.forename: A J
authors.initials: AJ
authors.lastname: Langlois
authors.forename: T J
authors.initials: TJ
authors.lastname: Matthews
authors.forename: K J
authors.initials: KJ
authors.lastname: Weinhold
authors.forename: S
authors.initials: S
authors.lastname: Chaffee
authors.forename: M
authors.initials: M
authors.lastname: Hershfield
authors.forename: D P
authors.initials: DP
authors.lastname: Bolognesi
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis*; D002460:Cell Line; D003124:Colorimetry; D006678:HIV / Q000276:immunology*; D015483:HIV Antibodies; D006801:Humans; D009500:Neutralization Tests / Q000379:methods*
chemical_list: D000914:Antibodies, Viral; D015483:HIV Antibodies