title: [Nonrandom karyotype changes in chemically induced tumors of the Djungarian hamster].
abstract: In the cells of tumors induced with methylcholanthrene in wild type and mutant (pink-eyed dilution) Djungarian hamsters non-random involvement in structural changes of certain chromosomes (Xp, 3p and 3q, 7q, 8q) was revealed. In addition, characteristic feature of the majority of tumors was varied number of double-minutes chromosomes (DMs). In some tumors, the markers with long homogeneously or differentially stained regions (HSRs and DSRs) were also present. The DMs, HSRs and DSRs are known as the structures containing amplified genes.
authors.forename: O I
authors.initials: OI
authors.lastname: Sokova
authors.forename: O E
authors.initials: OE
authors.lastname: Kulagina
authors.forename: E E
authors.initials: EE
authors.lastname: Pogosiants
mesh_terms: D015127:9,10-Dimethyl-1,2-benzanthracene; D000818:Animals; D002869:Chromosome Aberrations; D006224:Cricetinae; D005260:Female; D005819:Genetic Markers; D007621:Karyotyping; D008297:Male; D008748:Methylcholanthrene; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000235:genetics*; D012737:Sex Factors
chemical_list: D005819:Genetic Markers; D008748:Methylcholanthrene; D015127:9,10-Dimethyl-1,2-benzanthracene
vernacular_title: Nesluchaĭnye izmeneniia kariotipa v khimicheski indutsirovannykh opukholiakh dzhungarskogo khomiachka.