Sleep apnea in olivopontocerebellar degeneration: treatment with trazodone.
A 37-year-old man with a 19-year history of progressive autosomal-dominant olivopontocerebellar degeneration developed excessive daytime sleepiness and paroxysmal episodes that clinically resembled an ictal or postictal state. Polysomnography showed sleep apnea. Long-term therapy with trazodone resulted in resolution of the paroxysmal episodes, disappearance of daytime sleepiness, and gradual improvement of sleep architecture over several months.
Salazar-Grueso
E F
EF
Department of Neurology, University of Chicago, IL 60637.
Rosenberg
R S
RS
Roos
R P
RP
D000328:Adult; D006801:Humans; D008297:Male; D009849:Olivopontocerebellar Atrophies / Q000150:complications*; D012891:Sleep Apnea Syndromes / Q000188:drug therapy / Q000209:etiology*; D013132:Spinocerebellar Degenerations / Q000150:complications*; D014196:Trazodone / Q000627:therapeutic use*
D014196:Trazodone