Changes in blood flow of the middle cerebral artery during absence seizures.
Blood flow velocities (BFVs) of the middle cerebral artery were measured by transcranial Doppler blood flowmeter in 2 patients with childhood absence epilepsy; a total of 8 absence seizures were recorded. BFV began to decrease 7-9 sec after the appearance of diffuse bilateral 3 Hz spike-and-wave bursts on electroencephalography, reaching the trough 0-8 sec after the disappearance of spike-and-wave bursts which was followed by BFV recovery with rebound phenomenon. BFV then returned to the pre-ictal value within 1 min after the seizure ended. Pulsatility index increased in accordance with BFV decrease.
Sanada
S
S
Department of Child Neurology, Okayama University Medical School, Japan.
Murakami
N
N
Ohtahara
S
S
D000293:Adolescent; D001783:Blood Flow Velocity; D002536:Cerebral Arteries / Q000503:physiopathology; D002560:Cerebrovascular Circulation; D002648:Child; D004569:Electroencephalography; D004832:Epilepsy, Absence / Q000235:genetics / Q000503:physiopathology*; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D014463:Ultrasonography