Ampicillin in breast milk during puerperal infections.
Low concentrations of ampicillin were found in colostrum/breast milk from 6 mothers treated with pivampicillin 1.05 to 2.1 g daily during the first to eighth day postpartum in the maternity ward. It was calculated that the breast-fed infant could theoretically receive 0.05-0.37% of the dose/kg given to the mother. It is concluded that direct exposure of the breast-fed infant suckling from a mother under treatment with ampicillin or pivampicillin seems to be minimal.
Matheson
I
I
Department of Pharmacotherapeutics, University of Oslo, Norway.
Samseth
M
M
Sande
H A
HA
D000667:Ampicillin / Q000031:analogs & derivatives* / Q000032:analysis*; D005260:Female; D006801:Humans; D008895:Milk, Human / Q000032:analysis*; D010917:Pivampicillin / Q000378:metabolism / Q000627:therapeutic use*; D011247:Pregnancy; D011645:Puerperal Infection / Q000188:drug therapy / Q000378:metabolism*
D010917:Pivampicillin; D000667:Ampicillin