Preoperative serum CA-125 levels in patients with surgical stage I invasive ovarian adenocarcinoma.
Preoperative serum CA-125 levels were elevated in only three of 13 patients (23%) with a pelvic mass who were found to have surgical stage I invasive ovarian adenocarcinoma. This low incidence is surprising, since elevated levels have been found in greater than 80% of patients with advanced ovarian cancer. This suggests serious limitations for using serum CA-125 levels as a screening test for ovarian cancer.
Mann
W J
WJ
Department of Obstetrics and Gynecology, State University of New York, School of Medicine, Stony Brook 11794-8091.
Patsner
B
B
Cohen
H
H
Loesch
M
M
D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000951:Antigens, Neoplasm / Q000032:analysis*; D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor / Q000032:analysis*; D005260:Female; D006801:Humans; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery
D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor