Acute infectious lymphocytosis: phenotype of the proliferating cell.
A case of acute infectious lymphocytosis in an otherwise healthy 2-year-old child is reported. Marker analysis of the expanded blood lymphocytes showed that they were predominantly T cells and that there was a considerable increase in the helper/inducer phenotype (OKT4+) population. However, the lymphocyte response to polyclonal T-cell activators was low. This is the first report on T-cell subset distribution in acute infectious lymphocytosis.
Bertotto
A
A
de Felicis Arcangeli
C
C
Spinozzi
F
F
Gerli
R
R
Fabietti
G
G
Germini
G
G
Vaccaro
R
R
D000208:Acute Disease; D001402:B-Lymphocytes / Q000276:immunology; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008213:Lymphocyte Activation; D008218:Lymphocytosis / Q000235:genetics*; D010641:Phenotype; D013601:T-Lymphocytes / Q000276:immunology*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology