A new reagent for the preparation of glycoconjugates.
The thioglycoside derivative 2-carbazoylethyl 1-thio-beta-D-galactopyranoside hydrochloride was synthesized. Conversion of the carbazoyl group into the reactive azidocarbonyl function leads to a well suited reagent for the preparation of glycoconjugates via amidation of proteins or synthetic carriers in aqueous media.
Moroder
L
L
Max-Planck-Institut für Biochemie, Abteilung Peptidchemie, Martinsried bei München.
D006001:Glycoconjugates / Q000138:chemical synthesis*; D006023:Glycoproteins / Q000138:chemical synthesis; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013862:Thiogalactosides / Q000138:chemical synthesis*; D013865:Thioglycosides / Q000138:chemical synthesis*
D006001:Glycoconjugates; D006023:Glycoproteins; D007202:Indicators and Reagents; D013862:Thiogalactosides; D013865:Thioglycosides; C057203:(2-carbazoylethyl)-1-thio-beta-galactopyranoside