A case of partial sirenomelia and possible vitamin A teratogenesis.
Prenatal echographical findings of a partial sirenomelic fetus are described. An attempt was made to terminate pregnancy by administration of prostaglandin F2 alpha, but uterine rupture occurred. The teratogenic role of vitamin A ingested by the mother in the periconceptional period is discussed.
Von Lennep
E
E
El Khazen
N
N
De Pierreux
G
G
Amy
J J
JJ
Rodesch
F
F
Van Regemorter
N
N
D000014:Abnormalities, Drug-Induced / Q000175:diagnosis*; D000028:Abortion, Induced / Q000009:adverse effects; D000152:Acne Vulgaris / Q000188:drug therapy; D000328:Adult; D015237:Dinoprost; D004480:Ectromelia / Q000139:chemically induced* / Q000175:diagnosis; D005260:Female; D006801:Humans; D007668:Kidney / Q000002:abnormalities; D011247:Pregnancy; D011296:Prenatal Diagnosis; D011460:Prostaglandins F; D014463:Ultrasonography; D014597:Uterine Rupture / Q000209:etiology; D014801:Vitamin A / Q000009:adverse effects* / Q000627:therapeutic use
D011460:Prostaglandins F; D014801:Vitamin A; D015237:Dinoprost