title: Immunoscintigraphy of ovarian endometriosis. A preliminary study.
abstract: CA-125 is a membrane antigen detected in the serum of some women with gynaecological disease including endometriosis. We attempted to use a radioiodinated anti-CA-125 monoclonal antibody, OC-125, to image ovarian endometriosis using immunoscintigraphy. Two women with significant endometriosis and normal serum CA-125 levels had positive immunoscintigraphy. In one woman, all areas of endometriosis were imaged; in the other, endometriosis in one affected ovary was seen, but uptake in the other ovary was less than the extent of the disease.
authors.affiliation: John Radcliffe Hospital, Headington, Oxford.
authors.forename: S H
authors.initials: SH
authors.lastname: Kennedy
authors.forename: N D
authors.initials: ND
authors.lastname: Soper
authors.forename: O A
authors.initials: OA
authors.lastname: Mojiminiyi
authors.forename: B J
authors.initials: BJ
authors.lastname: Shepstone
authors.forename: D H
authors.initials: DH
authors.lastname: Barlow
mesh_terms: D000328:Adult; D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm / Q000276:immunology; D015295:Antigens, Tumor-Associated, Carbohydrate; D004715:Endometriosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging*; D010053:Ovary / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging
chemical_list: D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate