Paradoxical precipitation of tonic seizures by lorazepam in a child with atypical absence seizures.
A 10-year-old girl with Lennox-Gastaut syndrome who received intravenous lorazepam for atypical absence status seizures is reported. Tonic seizures occurred immediately and appeared to represent a paradoxical seizure exacerbation. We also review other patients with paradoxical seizure exacerbation by benzodiazepines.
DiMario
F J
FJ
Division of Neurology, Children's Hospital of Philadelphia, Pennsylvania.
Clancy
R R
RR
D002648:Child; D004832:Epilepsy, Absence / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008140:Lorazepam / Q000009:adverse effects*; D013226:Status Epilepticus / Q000139:chemically induced* / Q000503:physiopathology
D008140:Lorazepam