title: In vivo demonstration of flow recirculation and turbulence downstream of graded stenoses in canine arteries.
abstract: The velocity field around arterial stenoses was investigated using a pulsed doppler velocimeter in vivo. Asymmetric zones of recirculation were identified by systolic flow reversal in the post-stenotic field in carotid and iliac arteries of anesthetised dogs. There was a close correlation between shear intensity and turbulence as estimated by the velocity difference between the jet and the recirculation zone and by maximum spectral width respectively. Under the conditions of these experiments, stenosis grade (% diameter reduction) dominated hemodynamic variables such as Reynolds number, oscillation and pulsatility in determining the intensity of turbulence. The method used does not appear to have sufficient resolution to distinguish between turbulence and discrete oscillating velocities (vorticity) nor to allow determination of wall shear stress though the pattern of change of the latter is similar to that found downstream of axisymmetric stenosis in models using steady flow.
authors.forename: K J
authors.initials: KJ
authors.lastname: Hutchison
authors.forename: E
authors.initials: E
authors.lastname: Karpinski
mesh_terms: D000818:Animals; D001157:Arterial Occlusive Diseases / Q000503:physiopathology*; D001775:Blood Circulation; D004285:Dogs; D012212:Rheology