In-vitro activity of amoxycillin/clavulanic acid and five other oral antibiotics against clinical isolates of Haemophilus influenzae and Branhamella catarrhalis.
The in-vitro activity of amoxycillin/clavulanic acid, amoxycillin, erythromycin, doxycycline, chloramphenicol and cephalexin against 183 clinical isolates of Haemophilus influenzae and 61 of Branhamella catarrhalis was determined. Amoxycillin/clavulanic acid showed the greatest activity against H. influenzae. All isolates of B. catarrhalis were susceptible to amoxycillin/clavulanic acid, chloramphenicol, cephalexin and doxycycline.
Fernández-Roblas
R
R
Department of Clinical Microbiology, Fundación Jiménez Díaz, Madrid, Spain.
Jiménez Arriero
M
M
Rodriguez-Tudela
J L
JL
Soriano
F
F
D000658:Amoxicillin / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001424:Bacterial Infections / Q000382:microbiology; D002969:Clavulanic Acids / Q000494:pharmacology*; D006192:Haemophilus Infections / Q000382:microbiology; D006193:Haemophilus influenzae / Q000187:drug effects* / Q000201:enzymology; D006801:Humans; D008826:Microbial Sensitivity Tests; D001936:Moraxella catarrhalis / Q000187:drug effects* / Q000201:enzymology; D001618:beta-Lactamases / Q000378:metabolism
D000900:Anti-Bacterial Agents; D002969:Clavulanic Acids; D000658:Amoxicillin; D001618:beta-Lactamases