J chain is expressed by more IgA2- than IgA1-producing cells in colonic mucosa, but it is reduced in both subclasses in inflammatory bowel disease.
Kett
K
K
Laboratory for Immunohistochemistry and Immunopathology, University of Oslo, Rikshospitalet, Norway.
Brandtzaeg
P
P
D003093:Colitis, Ulcerative / Q000276:immunology*; D003106:Colon / Q000276:immunology; D003424:Crohn Disease / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000096:biosynthesis*; D007132:Immunoglobulin Isotypes / Q000096:biosynthesis; D007144:Immunoglobulin J-Chains / Q000502:physiology*; D007413:Intestinal Mucosa / Q000276:immunology*
D007070:Immunoglobulin A; D007132:Immunoglobulin Isotypes; D007144:Immunoglobulin J-Chains