title: Structural gene encoding human factor XII is located at 5q33-qter.
abstract: The gene encoding human factor XII (F12) or Hageman factor has been mapped to 5q33-qter. This has been achieved by analyzing the results obtained from hybridizing a cloned fragment from the factor XII gene to a panel of human-hamster somatic cell hybrid DNAs and also by in situ hybridization to normal human metaphase cells. The previously reported results localizing F12 to 6p23 are discussed.
authors.affiliation: Department of Human Genetics, University of Manitoba, Canada.
authors.forename: N J
authors.initials: NJ
authors.lastname: Royle
authors.forename: M
authors.initials: M
authors.lastname: Nigli
authors.forename: D
authors.initials: D
authors.lastname: Cool
authors.forename: R T
authors.initials: RT
authors.lastname: MacGillivray
authors.forename: J L
authors.initials: JL
authors.lastname: Hamerton
mesh_terms: D000818:Animals; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002895:Chromosomes, Human, Pair 5; D006224:Cricetinae; D005174:Factor XII / Q000235:genetics*; D005796:Genes; D006801:Humans; D006822:Hybrid Cells; D007621:Karyotyping; D012689:Sequence Homology, Nucleic Acid
chemical_list: D005174:Factor XII