[Effect of hydralazine on the respiratory function of the lungs and blood gas composition in patients with chronic obstructive bronchitis].
Hydralazine possesses a marked bronchodilating effect. In patients with bronchial obstruction determined by disorder of airway drainage function in combination with noticeable pulmonary sclerotic changes, the use of hydralazine in ineffective and can result in the deterioration of blood oxygenation. Hydralazine at a dose of 50 mg significantly exceeds euphylline at a dose of 0.3 g in the expression and duration of the bronchodilating effect.
Gavrisiuk
V K
VK
Feshchenko
Iu I
IuI
Iakhnitsa
T V
TV
D000328:Adult; D000402:Airway Obstruction / Q000188:drug therapy / Q000503:physiopathology; D001991:Bronchitis / Q000188:drug therapy* / Q000503:physiopathology; D001993:Bronchodilator Agents; D002245:Carbon Dioxide / Q000097:blood*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D006830:Hydralazine / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood*; D012119:Respiration / Q000187:drug effects*
D001993:Bronchodilator Agents; D002245:Carbon Dioxide; D006830:Hydralazine; D010100:Oxygen
Vliianie gidralazina na ventiliatsionnuiu funktsiiu legkikh i gazovyĭ sostav krovi u bol'nykh khronicheskim obstruktivnym bronkhitom.