title: Intralesional 5-fluorouracil for keratoacanthoma of the eyelid.
abstract: Keratoacanthoma of the lower eyelid developed in two patients. In the first case, conventional excision biopsy necessitated a large eyelid reconstruction procedure. In the second case, 5-fluorouracil was injected into the base of the keratoacanthoma. Both treatments resulted in complete resolution of the lesion with excellent cosmesis. Thus, intralesional 5-fluorouracil can be useful for keratoacanthomas of the eyelid in patients who are not good candidates for surgery.
authors.affiliation: Department of Surgery, Letterman Army Medical Center, Presidio of San Francisco, California 94129-6700.
authors.forename: D J
authors.initials: DJ
authors.lastname: Bergin
authors.forename: N A
authors.initials: NA
authors.lastname: Lapins
authors.forename: T A
authors.initials: TA
authors.lastname: Deffer
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005141:Eyelid Diseases / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005472:Fluorouracil / Q000627:therapeutic use*; D006801:Humans; D007636:Keratoacanthoma / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D013518:Surgery, Plastic
chemical_list: D005472:Fluorouracil