[Sensitivity of individual Drosophila to the mutagenic action of ethyl methanesulfonate].
The genetic effect of some factors is generally evaluated as an average response of all individuals, without taking into account their potential differences. The presence of individual sensitivity in separate Drosophila organisms to the mutagenic influence of ethyl methanesulfonate was shown when analysing recessive sex-linked lethal mutations in germ cells of males. Different sensitivity of separate individuals to mutagens reflects the existence of cryptic genetic variability in Drosophila strains on a large scale. It is advisable to take into account individual sensitivity of organisms to mutagenic factors, when conducting mutation research and studying genetic consequences of biosphere pollution.
Goncharova
R I
RI
Levina
A B
AB
Kuzhir
T D
TD
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004331:Drosophila melanogaster / Q000235:genetics*; D005020:Ethyl Methanesulfonate / Q000633:toxicity*; D005804:Genes, Lethal / Q000187:drug effects; D005854:Germ Cells / Q000187:drug effects; D008297:Male; D009153:Mutagens
D009153:Mutagens; D005020:Ethyl Methanesulfonate
Izuchenie chuvstvitel'nosti otdel'nykh osobeĭ Drozofily k mutagennomi deĭstviiu étilmetansul'fonata.