Lactate dehydrogenase isoenzyme-1 in the mediastinal yolk sac tumor.
LDH isozymes in both the serum and tumor tissues of 4 patients with mediastinal yolk sac tumors, and in the cystic content of tumors transplanted into nude mice was examined. Our findings suggested that LDH-1, along with AFP, is an important marker of this tumor, and that LDH isozyme study is necessary for its diagnosis.
Ito
M
M
Department of Thoracic Surgery, Kyoto University, Japan.
Taki
T
T
Mitsuoka
A
A
Miyake
M
M
D000293:Adolescent; D000328:Adult; D000818:Animals; D014408:Biomarkers, Tumor / Q000032:analysis*; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000032:analysis* / Q000096:biosynthesis; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis* / Q000201:enzymology / Q000601:surgery; D008649:Mesonephroma / Q000175:diagnosis* / Q000201:enzymology / Q000601:surgery; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation
D014408:Biomarkers, Tumor; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase