Caudal deficiency and asplenia anomalies in sibs.
The caudal deficiency and asplenia anomalies have been described separately in children. Two sibs with these two entities are described. Only another similar case, with caudal deficiency and polysplenia anomalies was found in the literature. It is possible that this association could be a new syndromic entity. An autosomal recessive mode of inheritance is suggested.
Fullana
A
A
Servicio de Neonatología, Clínica Infantil, La Paz, Facultad de Medicina, Universidad Autónoma de Madrid, Spain.
Garcia-Frias
E
E
Martinez-Frias
M L
ML
Razquin
S
S
Quero
J
J
D000015:Abnormalities, Multiple / Q000235:genetics* / Q000473:pathology; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D013116:Spinal Cord / Q000002:abnormalities*; D013154:Spleen / Q000002:abnormalities*