title: The status of sulphated isomers of glycosaminoglycans in fluorosed human teeth.
abstract: Fluorosed human teeth have lower concentrations of glycosaminoglycan (GAG) disaccharides and an increased dermatan sulphate content. Teeth from subjects with a high fluoride intake have a higher ratio of 4-sulphated to 6-sulphated GAGs. Increased dermatan sulphate may be an important factor in the clinical manifestations of fluorosis.
authors.affiliation: Department of Anatomy, All India Institute of Medical Sciences, New Delhi.
authors.forename: A K
authors.initials: AK
authors.lastname: Susheela
authors.forename: K
authors.initials: K
authors.lastname: Sharma
authors.forename: B P
authors.initials: BP
authors.lastname: Rajan
authors.forename: N
authors.initials: N
authors.lastname: Gnanasundaram
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002809:Chondroitin Sulfates / Q000032:analysis; D003871:Dermatan Sulfate / Q000032:analysis; D009050:Fluorosis, Dental / Q000378:metabolism*; D006025:Glycosaminoglycans / Q000032:analysis*; D006801:Humans; D007536:Isomerism
chemical_list: D006025:Glycosaminoglycans; D003871:Dermatan Sulfate; D002809:Chondroitin Sulfates