title: [Liquid intake measurement based on deuterium dilution].
abstract: Studies were carried out to ascertain methodological aspects and the validity of the deuterium dilution technique to determine maternal milk intake. Our study, conducted in 2-3 months-old normal infants, indicated that isotopic equilibrium is reached 6-8 hours after administration of an initial dose of 16.5% deuterium solution. Comparisons of liquid intake measured on a group of infants recovering from marasmic undernutrition, by the isotopic method and by direct recording of bottle-fed milk, revealed a good correlation of the respective values when the infants' body water was estimated using the Friis-Hansen formula. These findings suggest that the deuterium dilution technique is a valuable alternative to the current methods used to the measurement of maternal milk intake.
authors.affiliation: Departamento de Física, Facultad de Ciencias, Universidad de Chile, Casilla, Santiago.
authors.forename: C
authors.initials: C
authors.lastname: Infante
authors.forename: W
authors.initials: W
authors.lastname: Lara
authors.forename: F
authors.initials: F
authors.lastname: Mardones
authors.forename: P
authors.initials: P
authors.lastname: Rosso
authors.forename: F
authors.initials: F
authors.lastname: Vio
mesh_terms: D001834:Body Water / Q000378:metabolism*; D003903:Deuterium; D006801:Humans; D007223:Infant; D013058:Mass Spectrometry; D008895:Milk, Human / Q000378:metabolism*; D011502:Protein-Energy Malnutrition / Q000378:metabolism*; D011865:Radioisotope Dilution Technique; D012463:Saliva / Q000737:chemistry
chemical_list: D003903:Deuterium
vernacular_title: Medición de ingesta de líquidos en base a la dilución del deuterio.