[Postinfectious thrombocytosis as an acute phase reaction: the example of Haemophilus influenzae meningitis].
The postinfectious thrombocytosis occurring in 11 children with Haemophilus influenzae meningitis and/or septicaemia shows regular progress. The rise of thrombocyte concentrations starts around the 5th day after onset of antibiotic therapy, reaches values above 500,000/microliter between the 9th and 12th day, and relapses afterwards to normal values, which are reached around the 20th day. The range of thrombocytosis is influenced by the severity and complications (subdural effusions, secondary infection) of the infection as well as by the age of the patient. An inverse course of serum concentrations of C-reactive protein and thrombocyte concentrations points to the influence of this humoral reaction on the thrombocytic acute phase reaction.
Heyne
K
K
Klinik für Pädiatrie, Medizinischen Universität zu Lübeck.
Tegtmeyer
F K
FK
D000210:Acute-Phase Reaction / Q000209:etiology*; D002097:C-Reactive Protein / Q000378:metabolism; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007249:Inflammation / Q000209:etiology*; D008297:Male; D008583:Meningitis, Haemophilus / Q000150:complications*; D010976:Platelet Count; D011446:Prospective Studies; D013922:Thrombocytosis / Q000209:etiology*
D002097:C-Reactive Protein
Postinfektiöse Thrombozytose als Akute Phase-Reaktion: das Beispiel Haemophilus influenzae-Meningitis.