[The paraneoplastic syndrome in nasopharynx cancer. 32 cases].
Thirty-two cases of paraneoplastic syndrome associated with nasopharyngeal carcinoma are reported. The prevalence of the syndrome in young subjects was striking: 29 of the patients were under 25 years of age. Seventeen presented with hypertrophic osteoarthropathy, 13 with clubbing of the fingers, 1 with dermatomyositis and 1 with myelemia due to excessive production of bone marrow cells. Twenty-eight patients had metastases which involved the lung in 24. These pulmonary metastases are held responsible for the osteoarticular paraneoplastic syndrome, but in our 4 patients without metastases the syndrome was probably caused by the primary tumour itself.
Maalej
M
M
Ladgham
A
A
Ennouri
A
A
Ben Attia
A
A
Cammoun
M
M
Ellouze
R
R
D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000556:secondary; D002648:Child; D003882:Dermatomyositis / Q000209:etiology; D005260:Female; D006402:Hematologic Diseases / Q000209:etiology; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000503:physiopathology*; D010005:Osteoarthropathy, Secondary Hypertrophic / Q000209:etiology; D010257:Paraneoplastic Syndromes / Q000503:physiopathology*; D013997:Time Factors
Le syndrome paranéoplasique du cancer du nasopharynx. Trente-deux observations.