Allergic blepharoconjunctivitis due to phenylephrine.
Acute allergic blepharoconjunctivitis with mucopurulent discharge due to phenylephrine eye drops is reported. The reaction begins 3-4 hours after drug application, persists for 12 hours and regresses gradually within 72 hours. This clinical picture occurs with a phenylephrine concentration as low as 0.1%. Conjunctival biopsy of the inflamed eyes reveals marked infiltration by lymphocytes, plasma cells and eosinophiles, without predominance of any of these cells.
Geyer
O
O
Ichilov Hospital, Tel-Aviv, Israel.
Yust
I
I
Lazar
M
M
D000208:Acute Disease; D001762:Blepharitis / Q000139:chemically induced* / Q000473:pathology; D003233:Conjunctivitis, Allergic / Q000139:chemically induced* / Q000473:pathology; D004342:Drug Hypersensitivity / Q000209:etiology* / Q000473:pathology; D005141:Eyelid Diseases / Q000139:chemically induced*; D006801:Humans; D009883:Ophthalmic Solutions; D010656:Phenylephrine / Q000009:adverse effects*; D013492:Suppuration
D009883:Ophthalmic Solutions; D010656:Phenylephrine