title: [Absence, in the hypertrophied rat heart caused by aortocaval fistula, of several metabolic and electrophysiological changes seen in other models of hypertrophy].
abstract: In this work, we compared the electrophysiological and metabolic parameters of a volume overload model of cardiac hypertrophy (aorto-caval fistula) with those of two other models of hypertrophy (aortic stenosis and isoproterenol pretreatment). In these last models, a prolongation of action potential and a decrease of myocardial ATP content are observed. However, these alterations are not shown in the aorto-caval fistulated animals while their heart are well hypertrophied. The amplitude increase of phase 3 AP seemed to be a common factor of these models of cardiac hypertrophy.
authors.forename: C
authors.initials: C
authors.lastname: Thollon
authors.forename: J
authors.initials: J
authors.lastname: Aussedat
authors.forename: J
authors.initials: J
authors.lastname: Verdetti
authors.forename: P
authors.initials: P
authors.lastname: Kreher
mesh_terms: D000200:Action Potentials; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D001012:Aorta, Abdominal / Q000601:surgery; D001024:Aortic Valve Stenosis; D006332:Cardiomegaly / Q000378:metabolism / Q000503:physiopathology*; D004195:Disease Models, Animal; D004594:Electrophysiology; D005260:Female; D006321:Heart / Q000503:physiopathology*; D007545:Isoproterenol / Q000008:administration & dosage; D009206:Myocardium / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D014684:Venae Cavae / Q000601:surgery
chemical_list: D000255:Adenosine Triphosphate; D007545:Isoproterenol
vernacular_title: Absence chez le coeur de rat hypertrophié par fistule aorto-cave de certaines altérations métaboliques et électrophysiologiques observées dans le cas d'autres modèles d'hypertrophie.