Morbilliform erythrodermic fever with purpura. A benign eruptive fever occurring in 6 elderly women.
A febrile exanthem, hitherto unfamiliar, is reported in 6 elderly women. The rash itself is rather characteristic, and remarkable for its striking extent. It is a purpuric, morbilliform eruption dependent upon arteriocapillary damage in the skin, followed by the development of vast sheets of cyanotic erythema and an ultimate scarlatiniform desquamation. Cerebral and renal changes accompany the exanthem. At present the cause is not established. Drugs and viruses are to be considered. The disease is readily halted in the latter stages by systemic corticosteroids.
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D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D003873:Dermatitis, Exfoliative / Q000188:drug therapy / Q000473:pathology; D005076:Exanthema / Q000188:drug therapy / Q000473:pathology; D005260:Female; D005334:Fever; D006801:Humans; D008875:Middle Aged; D009543:Nifedipine / Q000009:adverse effects; D011693:Purpura / Q000188:drug therapy / Q000473:pathology; D012867:Skin / Q000473:pathology
D000305:Adrenal Cortex Hormones; D009543:Nifedipine