title: Cutaneous malignant melanoma in a black patient with neurofibromatosis (von Recklinghausen's disease).
abstract: A unique case of a cutaneous malignant melanoma arising in a black man with a familial history of neurofibromatosis (von Recklinghausen's disease) is reported. Although neurofibromatosis is believed to be a disorder of neural crest origin that is associated with a number of different malignancies, a definite association of malignant melanoma with neurofibromatosis has not been reported. The presence of a malignant melanoma arising on the trunk of a black man suggests an association of cutaneous malignant melanoma and neurofibromatosis--a malignancy and genodermatosis, respectively--of ultimate neural crest origin.
authors.affiliation: Department of Clinical Pathology and Diagnostic Medicine, East Carolina University School of Medicine, Greenville, North Carolina 27834.
authors.forename: J F
authors.initials: JF
authors.lastname: Silverman
authors.forename: M
authors.initials: M
authors.lastname: Blahove
authors.forename: J L
authors.initials: JL
authors.lastname: Collins
authors.forename: H T
authors.initials: HT
authors.lastname: Norris
mesh_terms: D000328:Adult; D044383:Black People; D006801:Humans; D008297:Male; D008545:Melanoma / Q000235:genetics / Q000473:pathology*; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009456:Neurofibromatosis 1 / Q000235:genetics / Q000473:pathology*; D012878:Skin Neoplasms / Q000235:genetics / Q000473:pathology*