title: WHO international reference reagents for human proinsulin and human insulin C-peptide.
abstract: Candidate preparations for international reference reagents for immunoassays of human proinsulin and human insulin C-peptide were evaluated in an international collaborative study. With the authorization of the Expert Committee on Biological Standardization of WHO, the following preparations were established as international reference reagents: human proinsulin (84/611, nominal ampoule content 6 micrograms) and human insulin C-peptide (84/510, 10 micrograms). Each preparation is intended as a primary reference reagent for the calibration of immunoassays.
authors.affiliation: National Institute for Biological Standards and Control, South Mimms, Potters Bar, Herts.
authors.forename: A F
authors.initials: AF
authors.lastname: Bristow
authors.forename: R E
authors.initials: RE
authors.lastname: Das
mesh_terms: D002096:C-Peptide / Q000592:standards*; D002138:Calibration; D006801:Humans; D007118:Immunoassay; D007202:Indicators and Reagents; D011384:Proinsulin / Q000592:standards*; D012015:Reference Standards; D014944:World Health Organization
chemical_list: D002096:C-Peptide; D007202:Indicators and Reagents; D011384:Proinsulin