Gallium uptake in the thyroid gland in amiodarone-induced hyperthyroidism.
Amiodarone is an iodinated antiarrhythmic agent that is effective in the treatment of atrial and ventricular arrhythmias. A number of side effects are seen, including pulmonary toxicity and thyroid dysfunction. A patient with both amiodarone-induced pneumonitis and hyperthyroidism who exhibited abnormal gallium activity in the lungs, as well as diffuse gallium uptake in the thyroid gland is presented. The latter has not been previously reported and supports the concept of iodide-induced "thyroiditis" with gallium uptake reflecting the inflammatory response.
Ling
M C
MC
Section of Nuclear Medicine (Department of Radiology), University of California, San Francisco.
Dake
M D
MD
Okerlund
M D
MD
D000638:Amiodarone / Q000009:adverse effects*; D005710:Gallium Radioisotopes / Q000493:pharmacokinetics; D006801:Humans; D006980:Hyperthyroidism / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000378:metabolism; D011877:Radionuclide Imaging; D013961:Thyroid Gland / Q000000981:diagnostic imaging* / Q000378:metabolism
D005710:Gallium Radioisotopes; D000638:Amiodarone