title: Hyaline cartilage-origin bone and soft-tissue neoplasms: MR appearance and histologic correlation.
abstract: Magnetic resonance (MR) images and histologic studies of 16 chondroid-matrix lesions were reviewed to determine if any distinctive morphologic or signal features might be discerned. Ten biopsy-proved nonchondroid bone lesions were compared in terms of configuration and signal characteristics. The tumor matrix had a distinctive appearance of homogeneous high signal intensity in a defined lobular configuration on images of all hyaline cartilage lesions obtained with a long repetition time and a long echo time. The areas of hyperintensity relative to muscle corresponded to areas of hyaline cartilage matrix with its uniform composition, low cellularity, and high water content; the lobular morphologic characteristic had an identical histologic correlate. The chondroblastomas, clear-cell chondrosarcoma, and synovial chondromatosis demonstrated a much more cellular stroma, with only scattered islands of chondroid matrix, and were isointense or hypointense compared with muscle on all MR sequences. The distinctive lobular, high-intensity MR appearance was not seen in the ten nonchondroid bone lesions.
authors.affiliation: Department of Radiology, David W. Devon Medical Imaging Center, Philadelphia, PA.
authors.forename: E K
authors.initials: EK
authors.lastname: Cohen
authors.forename: H Y
authors.initials: HY
authors.lastname: Kressel
authors.forename: T S
authors.initials: TS
authors.lastname: Frank
authors.forename: M
authors.initials: M
authors.lastname: Fallon
authors.forename: D L
authors.initials: DL
authors.lastname: Burk
authors.forename: M K
authors.initials: MK
authors.lastname: Dalinka
authors.forename: M L
authors.initials: ML
authors.lastname: Schiebler
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000175:diagnosis / Q000473:pathology*; D002648:Child; D002812:Chondroma / Q000175:diagnosis / Q000473:pathology*; D002813:Chondrosarcoma / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D012516:Osteosarcoma / Q000175:diagnosis / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000473:pathology*