title: Genetics of Alport's syndrome.
abstract: The pattern of inheritance of Alport's syndrome has been controversial for some time. Recent studies have clarified the mode of inheritance in this disease. Alport's syndrome is a heterogeneous disorder made up of a number of genetically distinct syndromes, with an autosomal dominant, an X-linked dominant and a rare autosomal recessive form. Clinical analysis shows that there are many distinct forms with or without nerve deafness, and with early or late occurrence of end-stage renal disease.
authors.affiliation: Unité de Recherches de Génétique Epidémiologique, Château de Longchamp, Paris, France.
authors.forename: J
authors.initials: J
authors.lastname: Feingold
authors.forename: E
authors.initials: E
authors.lastname: Bois
mesh_terms: D006801:Humans; D009394:Nephritis, Hereditary / Q000235:genetics*