title: N-acetyl endorphin in rat spermatogonia and primary spermatocytes.
abstract: In previous reports modest levels of beta-endorphin have been found by radioimmunoassay in rat testis, and localized by immunofluorescence to the interstitial cells. We have confirmed these previous reports and extended them by showing that the majority of testicular endorphins are acetylated forms, N-acetyl gamma-endorphin, N-acetyl alpha-endorphin, and N-acetyl beta-endorphin1-27. In addition, N-acetylated endorphins are not found in interstitial cells, but are confined to spermatogonia and primary spermatocytes.
authors.forename: M C
authors.initials: MC
authors.lastname: Cheng
authors.forename: J A
authors.initials: JA
authors.lastname: Clements
authors.forename: A I
authors.initials: AI
authors.lastname: Smith
authors.forename: S J
authors.initials: SJ
authors.lastname: Lolait
authors.forename: J W
authors.initials: JW
authors.lastname: Funder
mesh_terms: D000375:Aging; D000818:Animals; D004723:Endorphins / Q000032:analysis*; D005455:Fluorescent Antibody Technique; D007985:Leydig Cells / Q000032:analysis / Q000502:physiology; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013090:Spermatocytes / Q000032:analysis* / Q000502:physiology; D013093:Spermatogonia / Q000032:analysis* / Q000502:physiology; D013094:Spermatozoa / Q000032:analysis*; D001615:beta-Endorphin
chemical_list: D004723:Endorphins; D001615:beta-Endorphin; C040967:N-acetyl-gamma-endorphin; C040082:N-acetyl-alpha-endorphin