Modulation of hepatic cytochrome P-450 and DT-diaphorase by oral and sub-cutaneous administration of the pro-oxidant fungicide dichlone (2,3-dichloro-1,4-naphthoquinone).
Elliott
A J
AJ
Department of Biochemistry, University of Nevada-Reno 89557-0014.
Pardini
R S
RS
D000284:Administration, Oral; D000815:Aniline Hydroxylase / Q000378:metabolism; D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D005260:Female; D005659:Fungicides, Industrial / Q000378:metabolism / Q000633:toxicity*; D007279:Injections, Subcutaneous; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D008930:Mitochondria, Liver / Q000201:enzymology; D016660:NAD(P)H Dehydrogenase (Quinone); D009285:Naphthoquinones / Q000378:metabolism / Q000633:toxicity*; D011808:Quinone Reductases / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D005659:Fungicides, Industrial; D009285:Naphthoquinones; D003577:Cytochrome P-450 Enzyme System; C007332:dichlone; D000815:Aniline Hydroxylase; D016660:NAD(P)H Dehydrogenase (Quinone); D011808:Quinone Reductases