Bronchial ciliogenesis and oral steroid treatment in patients with asthma.
The effect of steroids on the ciliogenesis of bronchial epithelium has not previously been studied in asthmatics. Bronchial biopsies were taken during bronchoscopy from five asthmatics before and after oral steroid treatment, and studied by transmission electron microscopy. Two untreated healthy subjects served as controls. After treatment, ciliogenesis was abundant in all patients.
Heino
M
M
Department of Pulmonary Medicine, Helsinki University Central Hospital, Finland.
Karjalainen
J
J
Ylikoski
J
J
Laitinen
A
A
Laitinen
L A
LA
D000284:Administration, Oral; D000328:Adult; D001249:Asthma / Q000188:drug therapy* / Q000473:pathology; D001980:Bronchi / Q000648:ultrastructure*; D002923:Cilia / Q000187:drug effects / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use*
D011239:Prednisolone