title: Intraocular pressure following intravitreal silicone oil injection.
abstract: The clinical features of 100 consecutive cases and the histopathology of six enucleated eyes, all having undergone silicone oil injection for complicated retinal detachments, were studied with regard to the incidence and mechanisms of postoperative intraocular pressure changes. Preoperatively, five patients had glaucoma and 35 had hypotony (7 mm Hg or less). Immediately after surgery, 43 patients had glaucoma and 14 had hypotony, while seven had glaucoma and 39 had hypotony in the late postoperative period (average follow-up of 1 year). In most cases, the mechanism of intraocular pressure change did not appear to be directly related to the presence of silicone, but rather to the preoperative status of the eye and other aspects of the vitreoretinal surgery. When silicone was a factor, the resulting intraocular pressure appeared to represent a balance between mechanisms obstructing aqueous outflow (pupillary block and the reaction to silicone bubbles in the anterior chamber angle) and mechanisms reducing aqueous production (cyclitic membranes and retinal detachment).
authors.affiliation: Duke University Eye Center, Duke University Medical Center, Durham, North Carolina 27710.
authors.forename: L L
authors.initials: LL
authors.lastname: Burk
authors.forename: M B
authors.initials: MB
authors.lastname: Shields
authors.forename: A D
authors.initials: AD
authors.lastname: Proia
authors.forename: B W
authors.initials: BW
authors.lastname: McCuen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D015353:Eye Enucleation; D005260:Female; D006801:Humans; D007267:Injections; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D012163:Retinal Detachment / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D012827:Silicone Oils / Q000009:adverse effects*
chemical_list: D012827:Silicone Oils