title: Polymorphic DNA markers linked to cystic fibrosis locus in 20 Italian nuclear families.
abstract: We report the haplotype characterization of 20 cystic fibrosis (CF) families for the allelic systems MET-H, D7S16, D7S13 and D7S8. Linkage disequilibrium between MET-H and CF was found in the population investigated. Twelve of the examined families were fully informative, 6 partially informative and 2 completely uninformative.
authors.affiliation: Cattedra di Genetica, Università di Urbino, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Novelli
authors.forename: L
authors.initials: L
authors.lastname: Potenza
authors.forename: A
authors.initials: A
authors.lastname: Ruzzo
authors.forename: B
authors.initials: B
authors.lastname: Dallapiccola
mesh_terms: D000483:Alleles; D002874:Chromosome Mapping; D003550:Cystic Fibrosis / Q000175:diagnosis* / Q000235:genetics; D004247:DNA / Q000032:analysis*; D005787:Gene Frequency; D008040:Genetic Linkage; D005819:Genetic Markers; D006239:Haplotypes; D006801:Humans; D007558:Italy; D009679:Nuclear Family; D010641:Phenotype; D011110:Polymorphism, Genetic; D011296:Prenatal Diagnosis
chemical_list: D005819:Genetic Markers; D004247:DNA