Aqueductal stenosis in neurofibromatosis.
Macrocrania (i.e., macrocephaly) is a common manifestation of von Recklinghausen neurofibromatosis (NF-1), occurring in approximately 30% of patients with this disorder. Megalencephaly is the usual basis for NF-1-associated macrocrania, although obstructive hydrocephalus secondary to a brain tumor or cranial vault dysplasia may occur. We describe 2 patients with NF-1 and aqueductal stenosis documented by CT scan. The incidence of aqueductal stenosis among our patients with NF-1 is 1%.
Riviello
J J
JJ
Department of Neurology, Alfred I. duPont Institute, Wilmington, Del.
Marks
H G
HG
Lee
M S
MS
Mandell
G A
GA
D000293:Adolescent; D001927:Brain Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D002535:Cerebral Aqueduct / Q000000981:diagnostic imaging*; D002675:Child, Preschool; D006801:Humans; D008297:Male; D009456:Neurofibromatosis 1 / Q000150:complications*; D014057:Tomography, X-Ray Computed