The secretor locus as a marker for prenatal prediction of myotonic dystrophy (DM).
To verify the reliability of secretor status for prenatal diagnosis of myotonic dystrophy (DM), 179 amniotic fluid samples were compared with saliva or urine samples of the infants by hemagglutination inhibition. While no discrepancies were observed, problems could arise with intermediate results. Additionally, secretor typing is only informative in 8.4% of patients.
Greiner
J
J
Institut für Anthropologie und Humangenetik Universität, Heidelberg, Federal Republic of Germany.
Spengler
D H
DH
Krüger
J
J
Tariverdian
G
G
D000017:ABO Blood-Group System; D000653:Amniotic Fluid / Q000032:analysis; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007231:Infant, Newborn; D009223:Myotonic Dystrophy / Q000175:diagnosis / Q000235:genetics*; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012463:Saliva / Q000032:analysis; D014556:Urine / Q000032:analysis
D000017:ABO Blood-Group System; D005819:Genetic Markers