The incidence of Down syndrome in northern Finland with special reference to maternal age.
The incidence of live-born children with Down syndrome was found to be 1.73/1000 (1:578) in northern Finland over the years 1965 to 1979. Despite a marked reduction in the proportion of older mothers, no significant change in the incidence was observed. Instead, an age-specific rise in the incidence for mothers aged 25 to 29 years could be shown during the last five-year period in years 1975 to 1979.
Leisti
J
J
Vahtola
L
L
Linna
S L
SL
Herva
R
R
Koskela
S L
SL
Vitali
M
M
D000328:Adult; D001723:Birth Rate; D004314:Down Syndrome / Q000453:epidemiology*; D004812:Epidemiologic Methods; D005260:Female; D005387:Finland; D006801:Humans; D008297:Male; D008423:Maternal Age; D008875:Middle Aged; D012621:Seasons