T(8;21) with a phenotype of chronic myeloid leukemia.
A myeloproliferative disorder having the phenotype of chronic myeloid leukemia (CML) with t(8;21) is reported. Neither t(9;22) nor a DNA rearrangement in the bcr region was detected. The presence of t(8;21), in contrast with previous experience, does not appear to prevent full maturation of the granulocytic series.
Raskind
W H
WH
Department of Medicine, University of Washington School of Medicine, Seattle 98195.
Papayannopoulou
T
T
Hammond
W P
WP
D000368:Aged; D002874:Chromosome Mapping; D004273:DNA, Neoplasm / Q000032:analysis; D005260:Female; D006801:Humans; D007621:Karyotyping; D007951:Leukemia, Myeloid / Q000235:genetics*; D010641:Phenotype
D004273:DNA, Neoplasm