T complex hemispheric asymmetries: effects of stimulus intensity.
The T complex component of the human auditory evoked potential (AEP) is thought to be produced in auditory cortex, on the posterior lateral surface of the temporal lobe. Recorded over temporal scalp, it consists of an 80-90 ms positive peak, Ta, and a 120-140 negative peak, Tb. As part of an effort to develop the clinical usefulness of the T complex in assessing auditory cortical function, we studied the effects of change in monaural stimulus intensity (20-80 dB SL) on T complex latency, amplitude, and hemispheric differences in normal adults. Ta and Tb peak latencies decreased as stimulus intensity increased. These latency changes were not dependent on ear or hemisphere. Right hemisphere Ta latency was shorter with contralateral than with ipsilateral stimulation; while left hemisphere Ta latency was not dependent on the ear stimulated. Tb latency was shorter over the left hemisphere, and over the contralateral hemisphere. Ta-b amplitude increased as stimulus intensity increased. This amplitude change was not dependent on ear or hemisphere. Ta-b amplitudes were larger over the right hemisphere and over the contralateral hemisphere. Hemispheric asymmetries were not significantly affected by stimulus intensity.
Cacace
A T
AT
Department of Surgery, Albany Medical College, New York 12208.
Dowman
R
R
Wolpaw
J R
JR
D000293:Adolescent; D000328:Adult; D001303:Auditory Cortex / Q000502:physiology*; D005072:Evoked Potentials, Auditory; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008144:Loudness Perception / Q000502:physiology; D008297:Male; D008875:Middle Aged; D011930:Reaction Time