Osler-Weber-Rendu disease in an infant.
A 23-month-old girl with Osler-Weber-Rendu (OWR) disease manifested by hemoptysis died of massive pulmonary hemorrhage. Autopsy showed predominant respiratory tract involvement, but telangiectatic vessels were also present in other sites. Skin lesions were absent. A grandfather had died after bleeding by mouth following physical exertion. This disease seldom appears in children and hemorrhage usually manifests after 30 years of age.
Reyes-Mújica
M
M
Department of Pathology, Instituto Nacional de Pediatría, DF, México.
López-Corella
E
E
Pérez-Fernández
L
L
Cuevas-Schacht
F
F
Carrillo-Farga
J
J
D005260:Female; D006801:Humans; D007223:Infant; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000473:pathology*