title: Reactive hyperemia monitored on rat muscle using perfluorocarbons and 19F NMR.
abstract: Perfluorinated blood substitutes can be detected by 19F NMR in vivo in small concentrations. Reactive hyperemia was induced in rat leg by the transient application of a tourniquet, causing a 50% increase in 19F NMR signal. These results show that this method can be used to monitor the kinetics of tissue perfusion.
authors.affiliation: DRF/SPh/RMBM, Centre d'Etudes Nucléaires de Grenoble, France.
authors.forename: B
authors.initials: B
authors.lastname: Authier
mesh_terms: D000818:Animals; D005466:Fluorocarbons; D006614:Hindlimb; D006940:Hyperemia / Q000209:etiology / Q000503:physiopathology*; D007511:Ischemia / Q000150:complications; D009682:Magnetic Resonance Spectroscopy; D009132:Muscles / Q000098:blood supply*; D051381:Rats; D012039:Regional Blood Flow
chemical_list: D005466:Fluorocarbons; C008807:perfluorotributylamine