[Influence of dietary protein levels on the electrophoretic pattern and plasma IgG and IgM levels in pregnant rats and their offspring].
In view of the influence that nutritional and physiological status exert on the immunological capacity of the subject, a study was carried out for the purpose of studying the changes induced by three protein levels in the diet: (4%, 10% (control), and 20%) on total plasma proteins (TPP) and their fractions, as well as Ig G and Ig M levels in non-pregnant (NP) and pregnant (P) rats and their offspring. Effect of the diet on adult rats--In non-pregnant rats submitted to the high protein diet, Ig G levels increased while TPP decreased in P rats fed on 4% and 20% protein diets. The higher the protein level in the diet, the higher were the TPP values. Effect of pregnancy--Ig G and Ig M levels suffered an increase in rats fed the 4% and 10% protein diets, while a decrease was observed in rats submitted to the 20% protein level diet. The TPP rate diminished in rats fed on the low protein diets, and increased when the highest protein diet was administered. Effect of the diet on offspring--Ig M levels were only detected in neonates from rats fed with the low and high protein diets. Moreover, the TPP rate increased as a direct function of the dietary protein intake.
Varela
P
P
Universidad Complutense, Madrid, España.
Muñoz-Martínez
E
E
Marcos
A
A
Unzaga
M T
MT
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology; D001797:Blood Protein Electrophoresis; D004032:Diet; D004044:Dietary Proteins / Q000008:administration & dosage* / Q000494:pharmacology; D005260:Female; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains
D004044:Dietary Proteins; D007074:Immunoglobulin G; D007075:Immunoglobulin M
Influencia del nivel proteínico dietario sobre el patrón electroforético y los niveles de Ig G e Ig M plasmáticos en ratas gestantes y sus neonatos.