Steroids excreted by human skin. II. C19-steroid sulphates in human axillary sweat.
Beside dehydroepiandrosterone sulphate and androsterone sulphate, 5-androstene-3 beta, 17 beta-diol-3-sulphate and testosterone sulphate were isolated and identified from the axillary sweat of sexually mature women and men. The quantities of these four C19-steroid sulphates were determined individually in the sweat of eight healthy, sexually mature women and men: dehydroepiandrosterone sulphate was found in the highest amount, it was followed by 5-androstene-3 beta, 17 beta-diol-3-sulphate and androsterone sulphate. Testosterone sulphate occurred in the lowest quantity, its excretion amounting to about one-thousandth of that of dehydroepiandrosterone sulphate. Study of the C19-steroid sulphates excreted by the apocrine sweat glands permitted an insight into the steroid metabolism in human skin, which presumably is, closely connected with the steroid hormones of peripheral blood.
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D000293:Adolescent; D000328:Adult; D015114:Androstenediol / Q000031:analogs & derivatives / Q000032:analysis*; D000734:Androstenediols / Q000032:analysis*; D000738:Androsterone / Q000031:analogs & derivatives* / Q000032:analysis; D001365:Axilla; D003687:Dehydroepiandrosterone / Q000031:analogs & derivatives* / Q000032:analysis; D019314:Dehydroepiandrosterone Sulfate; D005260:Female; D006801:Humans; D008297:Male; D012737:Sex Factors; D013542:Sweat / Q000032:analysis*; D013739:Testosterone / Q000031:analogs & derivatives* / Q000032:analysis
D000734:Androstenediols; D013739:Testosterone; D003687:Dehydroepiandrosterone; D019314:Dehydroepiandrosterone Sulfate; C033537:5-androstene-3 beta,17 beta-diol sulfate; C028627:testosterone-17-sulfate; D015114:Androstenediol; D000738:Androsterone; C026905:androsterone sulfate