title: Polyploid abnormalities in day 3 and day 5 merino sheep embryos.
abstract: The chromosome complement was assessed in Merino sheep embryos collected at 3 and 5 days after the onset of oestrus. Donor ewe treatments were: untreated, or immunized against androstenedione (day 3); and untreated, or treated with follicle-stimulating hormone (FSH), or treated with FSH plus immunization against androstenedione (day 5). No significant differences in the frequency of chromosomally abnormal embryos between treatment groups within each age group were observed, so the data have been combined. Euploid abnormalities were observed in 10.8% of the day-3 embryos (4/37), with the abnormalities being one 1n, one 3n and two 5n. Embryos with euploidy (10%) were also observed at day 5, with three 1n/2n mosaics and a 3n embryo present in a sample of 40. These data suggest that chromosomally aberrant embryos are not lost before day 5 of development.
authors.affiliation: Division of Animal Production, CSIRO, Blacktown, N. S. W.
authors.forename: J D
authors.initials: JD
authors.lastname: Murray
authors.forename: C D
authors.initials: CD
authors.lastname: Nancarrow
authors.forename: R J
authors.initials: RJ
authors.lastname: Scaramuzzi
authors.forename: Y
authors.initials: Y
authors.lastname: Cognie
mesh_terms: D000735:Androstenedione / Q000276:immunology; D000818:Animals; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D005260:Female; D005313:Fetal Death / Q000235:genetics; D005640:Follicle Stimulating Hormone / Q000494:pharmacology; D005865:Gestational Age; D007114:Immunization; D008297:Male; D011123:Polyploidy; D011247:Pregnancy; D012756:Sheep / Q000196:embryology*
chemical_list: D000735:Androstenedione; D005640:Follicle Stimulating Hormone