Suppression of lactation. A comparison of bromocriptine and prostaglandin E2.
Women in the puerperium who requested lactation suppression were randomly allocated to receive bromocriptine from puerperal day 1 to 14 or prostaglandin E2 from day 3 or 4 for 24 hours. Subjectively, lactation suppression was satisfactory in all cases. Objective measurements showed a trend toward more-effective early suppression with bromocriptine. After discharge from the hospital, 3 of the 21 women who received prostaglandin E2 complained of mild breast tenderness, whereas 10 of the 22 who received bromocriptine reported severe "rebound" breast tenderness.
England
M J
MJ
Department of Obstetrics and Gynaecology, Johannesburg Hospital, South Africa.
Tjallinks
A
A
Hofmeyr
J
J
Harber
J
J
D001971:Bromocriptine / Q000494:pharmacology*; D015232:Dinoprostone / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007774:Lactation / Q000187:drug effects*; D011247:Pregnancy; D011388:Prolactin / Q000097:blood
D001971:Bromocriptine; D011388:Prolactin; D015232:Dinoprostone