title: Pericentric inversion of chromosome 19 in three families.
abstract: Pericentric inversion of chromosome 19 has been found in several members of three unrelated families from a restricted geographical region. In one of the families, an additional pericentric inversion of chromosome 9 was observed. Reproductive problems, multiple abortions in two families and a neonatal death in the third, were present. A review of previously described cases is included, and the genetic risk connected with this type of rearrangement is also discussed.
authors.affiliation: Dipartimento di Medicina Interna e Sanità Pubblica, Università dell'Aquila, Italy.
authors.forename: E
authors.initials: E
authors.lastname: D'Alessandro
authors.forename: C
authors.initials: C
authors.lastname: De Matteis Vaccarella
authors.forename: M L
authors.initials: ML
authors.lastname: Lo Re
authors.forename: F
authors.initials: F
authors.lastname: Cappa
authors.forename: A
authors.initials: A
authors.lastname: D'Alfonso
authors.forename: S
authors.initials: S
authors.lastname: Discepoli
authors.forename: M R
authors.initials: MR
authors.lastname: Della Penna
authors.forename: G
authors.initials: G
authors.lastname: Del Porto
mesh_terms: D000022:Abortion, Spontaneous / Q000235:genetics*; D000328:Adult; D002871:Chromosome Banding; D007446:Chromosome Inversion; D002888:Chromosomes, Human, Pair 19; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D011247:Pregnancy; D012307:Risk Factors