title: Cervical dilatation by Lamicel before first trimester abortion: a clinical and experimental study.
abstract: Twenty women were treated with Lamicel tents for 4 h and 20 women for 16 h before vacuum aspiration in the first trimester of pregnancy. The shorter time of treatment was as effective as the longer time with respect to cervical softening and dilatation. In comparison with an untreated control group, Lamicel treatment was followed by an increased collagenolytic activity and increased sensitivity to prostaglandin E2 of the cervical smooth muscle.
authors.affiliation: University of Göteborg, Sahlgren's Hospital, Department of Obstetrics and Gynecology, Sweden.
authors.forename: A
authors.initials: A
authors.lastname: Norström
authors.forename: I
authors.initials: I
authors.lastname: Bryman
authors.forename: H A
authors.initials: HA
authors.lastname: Hansson
mesh_terms: D000032:Abortion, Therapeutic / Q000379:methods*; D002584:Cervix Uteri / Q000187:drug effects* / Q000648:ultrastructure; D004106:Dilatation; D015232:Dinoprostone; D005260:Female; D006801:Humans; D008278:Magnesium Sulfate / Q000627:therapeutic use*; D008854:Microscopy, Electron; D009119:Muscle Contraction / Q000187:drug effects; D009638:Norepinephrine / Q000494:pharmacology; D011142:Polyvinyl Alcohol / Q000627:therapeutic use*; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011458:Prostaglandins E / Q000494:pharmacology; D014619:Vacuum Curettage
chemical_list: C034860:Lamicel; D011458:Prostaglandins E; D008278:Magnesium Sulfate; D011142:Polyvinyl Alcohol; D015232:Dinoprostone; D009638:Norepinephrine