title: Isoprenoid (phosphinylmethyl)phosphonates as inhibitors of squalene synthetase.
authors.affiliation: Squibb Institute for Medical Research, Princeton, New Jersey 08543-4000.
authors.forename: S A
authors.initials: SA
authors.lastname: Biller
authors.forename: C
authors.initials: C
authors.lastname: Forster
authors.forename: E M
authors.initials: EM
authors.lastname: Gordon
authors.forename: T
authors.initials: T
authors.lastname: Harrity
authors.forename: W A
authors.initials: WA
authors.lastname: Scott
authors.forename: C P
authors.initials: CP
authors.lastname: Ciosek
mesh_terms: D000818:Animals; D004164:Diphosphonates / Q000494:pharmacology*; D013186:Farnesyl-Diphosphate Farnesyltransferase / Q000037:antagonists & inhibitors*; D007700:Kinetics; D008862:Microsomes, Liver / Q000201:enzymology; D009943:Organophosphorus Compounds / Q000494:pharmacology*; D010088:Oxidoreductases / Q000037:antagonists & inhibitors*; D011106:Polyisoprenyl Phosphates / Q000494:pharmacology*; D051381:Rats; D012717:Sesquiterpenes; D013729:Terpenes / Q000494:pharmacology*
chemical_list: D004164:Diphosphonates; D009943:Organophosphorus Compounds; D011106:Polyisoprenyl Phosphates; D012717:Sesquiterpenes; D013729:Terpenes; C004808:farnesyl pyrophosphate; D010088:Oxidoreductases; D013186:Farnesyl-Diphosphate Farnesyltransferase