The role of influenza virus haemagglutinin in membrane fusion.
An acid-induced conformational change in influenza virus haemagglutinin triggers the virus to fuse with the endosomal membrane of a host cell during infection. Structural aspects of this change are discussed along with the possible haemagglutinin-mediated processes which occur during membrane fusion.
Wharton
S A
SA
Division of Virology, National Institute for Medical Research, Mill Hill, London, UK.
D000595:Amino Acid Sequence; D006389:Hemagglutinins, Viral / Q000737:chemistry / Q000502:physiology*; D008561:Membrane Fusion / Q000502:physiology*; D008968:Molecular Conformation; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009975:Orthomyxoviridae / Q000502:physiology
D006389:Hemagglutinins, Viral