title: [Evaluation of erythrocyte survival by the determination of glycosylated hemoglobin. Clinical value].
abstract: In normoglycaemic subjects the haemoglobin glycosylation rate primarily depends on duration of erythrocyte life. Measurements of glycosylated haemoglobin therefore can be used to evaluate erythrocyte life. Indeed, glycosylated haemoglobin is significantly reduced (p less than 0.001) in patients with autoimmune haemolytic anaemia or Minkowski-Chauffard syndrome as compared with patients with non-haemolytic anaemia. In addition, there is a strong correlation (r = 0.92) in non-diabetic subjects between the level of glycosylated haemoglobin and the percentage of daily haemolysis, as determined by a method using 51 Cr-labelled antologous red cells.
authors.forename: D
authors.initials: D
authors.lastname: Rigal
authors.forename: M
authors.initials: M
authors.lastname: Monestier
authors.forename: M
authors.initials: M
authors.lastname: Baboin-Jaubert
authors.forename: D
authors.initials: D
authors.lastname: Chabaud-Sassoulas
authors.forename: G L
authors.initials: GL
authors.lastname: Marseglia
authors.forename: D
authors.initials: D
authors.lastname: Ville
authors.forename: F
authors.initials: F
authors.lastname: Meyer
authors.forename: A
authors.initials: A
authors.lastname: Jouvenceaux
mesh_terms: D000740:Anemia / Q000097:blood*; D000743:Anemia, Hemolytic / Q000097:blood*; D002860:Chromium Radioisotopes; D004905:Erythrocyte Aging; D004912:Erythrocytes / Q000000981:diagnostic imaging; D006442:Glycated Hemoglobin / Q000032:analysis*; D006461:Hemolysis; D006801:Humans; D011877:Radionuclide Imaging
chemical_list: D002860:Chromium Radioisotopes; D006442:Glycated Hemoglobin
vernacular_title: Appréciation de la durée de vie des globules rouges par le dosage de l'hémoglobine glycosylée. Intérêt clinique.