title: The Iridovirus frog virus 3: a model for trans-acting proteins.
abstract: The amphibian Iridovirus, frog virus 3 (FV3), produces at least two trans-activating proteins that stimulate the expression of viral genes. One of these proteins induces transcription from the promoter of an immediate-early FV3 gene, whereas the other induces transcription from exogenously methylated DNA. These proteins may serve as a model for both viral and cellular trans-acting factors.
authors.affiliation: Department of Virology and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.
authors.forename: D B
authors.initials: DB
authors.lastname: Willis
authors.forename: J P
authors.initials: JP
authors.lastname: Thompson
mesh_terms: D001483:Base Sequence; D004279:DNA, Viral / Q000378:metabolism; D015967:Gene Expression Regulation, Viral; D007497:Iridoviridae / Q000235:genetics*; D008745:Methylation; D011401:Promoter Regions, Genetic; D015534:Trans-Activators / Q000378:metabolism*; D014158:Transcription, Genetic
chemical_list: D004279:DNA, Viral; D015534:Trans-Activators