title: Streptokinase in a loculated pleural effusion. Effectiveness determined by site of instillation.
abstract: A patient with a large loculated pleural effusion had streptokinase instilled into the loculation, and this was ineffective; however, when the same amount of streptokinase was instilled into the space around the loculation, there was rapid lysis of the loculation, resulting in the drainage of purulent fluid through the chest tube.
authors.affiliation: Department of Medicine, Albert Einstein College of Medicine-Montefiore Medical Center, Bronx, NY.
authors.forename: R G
authors.initials: RG
authors.lastname: Ogirala
authors.forename: M H
authors.initials: MH
authors.lastname: Williams
mesh_terms: D000328:Adult; D004322:Drainage / Q000379:methods; D006801:Humans; D007322:Instillation, Drug; D008297:Male; D010996:Pleural Effusion / Q000000981:diagnostic imaging / Q000601:surgery*; D011859:Radiography; D013300:Streptokinase / Q000008:administration & dosage*
chemical_list: D013300:Streptokinase