title: Studies on selenium in top athletes.
abstract: The authors performed a controlled trial in 18 top athletes (9 weight lifters and 9 rowers, girls) in order to make evident some chronic and acute effects (antioxidant) of selenium. Nonprotein--SH (essential glutathione), lipid peroxides (MDA-malondialdehyde), glucose-6-phosphate dehydrogenases (G-6-PDH) and fructose-1,6-diphosphate aldolase in serum, have been recorded initially on basal conditions, after 3 weeks of treatment (100 micrograms/day selenium or placebo) and again after 3 weeks of treatment, also on basal conditions, when crossing over the groups (between a free interval of 10 days). In another trial we registered these parameters on basal conditions and after two hours of hard training accompanied by a per oral administration of 150 micrograms selenium (respectively placebo). The results show significant changes under selenium treatment of the peroxides, G-6-PDH and light changes, not significant of the nonprotein--SH, changes which could suggest an antioxidant effect of this element.
authors.affiliation: Faculty of Medicine, Sports Medicine Department, Bucharest.
authors.forename: I
authors.initials: I
authors.lastname: Drâgan
authors.forename: E
authors.initials: E
authors.lastname: Ploeşteanu
authors.forename: E
authors.initials: E
authors.lastname: Cristea
authors.forename: M
authors.initials: M
authors.lastname: Mohora
authors.forename: V
authors.initials: V
authors.lastname: Dinu
authors.forename: V S
authors.initials: VS
authors.lastname: Troescu
mesh_terms: D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic; D005260:Female; D005634:Fructose-Bisphosphate Aldolase / Q000097:blood; D005954:Glucosephosphate Dehydrogenase / Q000097:blood; D005978:Glutathione / Q000097:blood; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D008054:Lipid Peroxides / Q000097:blood; D011446:Prospective Studies; D011897:Random Allocation; D012643:Selenium / Q000627:therapeutic use*; D013177:Sports; D013997:Time Factors; D014891:Weight Lifting
chemical_list: D008054:Lipid Peroxides; D005954:Glucosephosphate Dehydrogenase; D005634:Fructose-Bisphosphate Aldolase; D005978:Glutathione; D012643:Selenium