Erythrocyte lipid peroxidation, glutathione and vitamin E levels in cholesterol-fed rats.
Erythrocyte cholesterol and phospholipid levels, the susceptibility of erythrocytes to lipid peroxidation as well as erythrocyte glutathione and vitamin E levels were determined in rats fed a high cholesterol (2%, w/w) and high cholic acid (0.5%, w/w) diet for 3 months. Cholesterol feeding caused an increase in erythrocyte cholesterol levels, but no change was observed in erythrocyte phospholipid levels. Dietary cholesterol did not alter the susceptibility of erythrocytes to lipid peroxidation as well as erythrocyte glutathione and vitamin E levels in rats.
Uysal
M
M
Department of Biochemistry, Istanbul Faculty of Medicine, University of Istanbul, Turkey.
Seçkin
S
S
Kutalp
G
G
Koçak-Toker
N
N
D000818:Animals; D002791:Cholesterol, Dietary / Q000494:pharmacology*; D004912:Erythrocytes / Q000378:metabolism*; D005978:Glutathione / Q000097:blood*; D008054:Lipid Peroxides / Q000097:blood*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D014810:Vitamin E / Q000097:blood*
D002791:Cholesterol, Dietary; D008054:Lipid Peroxides; D014810:Vitamin E; D005978:Glutathione