Serial serum calcitonin concentrations to evaluate response to therapy of patients with medullary thyroid carcinoma.
Six female patients with medullary thyroid carcinoma were treated with doxorubicin (50 mg/m2) and cis-diammine dichloroplatinum (70 mg/m2) every three weeks. No patient responded to therapy as was suggested by serial serum calcitonin concentrations before and after treatment.
Athanassiades
P
P
Athens University, Department of Clinical Therapeutics, Alexandra Hospital, Greece.
Piperingos
G
G
Pandos
P
P
Koutras
D
D
Moulopoulos
S
S
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols; D002116:Calcitonin / Q000097:blood*; D002277:Carcinoma / Q000097:blood / Q000188:drug therapy*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008875:Middle Aged; D008991:Monitoring, Physiologic; D013964:Thyroid Neoplasms / Q000097:blood / Q000188:drug therapy*; D013965:Thyroidectomy; D013974:Thyroxine / Q000627:therapeutic use
D004317:Doxorubicin; D002116:Calcitonin; D002945:Cisplatin; D013974:Thyroxine