In vivo sister chromatid exchange induced by 1,2-dichloroethane on bone marrow cells of mice.
In vivo sister chromatid exchange induced by 1,2-dichloroethane (DCE) was studied in bone marrow cells of mice after acute treatment for 24 hr. With the exception of the lowest concentration (0.5 mg/kg), each treated series exhibited a statistically significant increase in SCEs when compared with the control.
Giri
A K
AK
Department of Botany, University of Calcutta.
Que Hee
S S
SS
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects*; D001854:Bone Marrow Cells; D004305:Dose-Response Relationship, Drug; D005025:Ethylene Dichlorides / Q000633:toxicity*; D006843:Hydrocarbons, Chlorinated / Q000633:toxicity*; D008297:Male; D051379:Mice; D012854:Sister Chromatid Exchange / Q000187:drug effects*
D005025:Ethylene Dichlorides; D006843:Hydrocarbons, Chlorinated; C024565:ethylene dichloride