[Information concerning radiation-induced sarcomas. Report on 2 cases].
Two cases of radiation-induced sarcomas are presented. Osteosarcomas developed in the frontal bone after a latency period of 36 years following operation for brain tumor with post-operative irradiation (48 Gy) in one patient and in the region of the right sacro-iliac joint after ablation of testis for seminoma with post-operative irradiation (60 Gy) in another patient. In the literature, the risk of developing an irradiation-induced sarcoma is considered to be low (0.05-0.2%). Both cases, however, underline the necessity of an exact indication for irradiation to avoid such complications.
Schmidt
A
A
Institut für Pathologie, Friedrich-Schiller-Universität Jena.
Kob
D
D
Kosmehl
H
H
D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000473:pathology*; D001932:Brain Neoplasms / Q000532:radiotherapy; D003131:Combined Modality Therapy; D004407:Dysgerminoma / Q000532:radiotherapy; D005624:Frontal Bone / Q000473:pathology* / Q000528:radiation effects; D006801:Humans; D007085:Ilium / Q000473:pathology* / Q000528:radiation effects; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000473:pathology*; D012516:Osteosarcoma / Q000473:pathology*; D012888:Skull Neoplasms / Q000473:pathology*; D013736:Testicular Neoplasms / Q000532:radiotherapy
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