Emergency coronary artery bypass graft surgery for threatened acute myocardial infarction related to coronary artery catheterization.
In 20 patients undergoing cardiac catheterization, usually involving balloon-catheter dilation or streptokinase infusion, catheter-induced coronary artery intimal damage resulted in severe chest pain, electrocardiographic evidence of obstruction or dissection of a major coronary artery. These patients were surgically revascularized within 8 hours after the onset of the acute chest pain syndrome. Our experience with pharmacological and catheter-related manipulations to improve coronary blood flow after the ischemic episode but before operation suggested that the additional time spent in the catheterization laboratory was worthwhile. The injured coronary artery was the left anterior descending in 10 patients, the right in 8, the left main in 1 patient, and an obtuse marginal branch of the circumflex in 1. The average number of grafts per patient was 2.5; only 6 patients had single bypass grafts. In 5 patients, intraaortic balloon pumping was used either preoperatively or postoperatively. Inotropic support was used postoperatively in 5 patients, and 7 patients received lidocaine for ventricular irritability. Abnormal elevation of the serum isoenzyme of creatine kinase (CK-MB) was seen in 8 patients, and new Q waves were noted in 4 patients; 3 of these 4 patients with new Q waves also had abnormal serum CK-MB levels. Global ejection fraction obtained by the equilibrium-gated blood pool scan postoperatively was 60 +/- 3%, which was similar to the 62 +/- 3% obtained from the contrast-determined ventriculogram done preoperatively prior to the catheter-related injury. There were no early or late deaths, but morbidity was much higher in the group who had emergency coronary artery bypass grafting (CABG) compared with those who had elective CABG.(ABSTRACT TRUNCATED AT 250 WORDS)
Roberts
A J
AJ
Faro
R S
RS
Rubin
M R
MR
Pepine
C J
CJ
Feldman
R L
RL
Ellison
D W
DW
LoPresti
J
J
Staples
E D
ED
Knauf
D G
DG
Alexander
J A
JA
D000800:Angioplasty, Balloon / Q000009:adverse effects; D006328:Cardiac Catheterization / Q000009:adverse effects*; D001026:Coronary Artery Bypass; D004562:Electrocardiography; D004630:Emergencies; D006439:Hemodynamics; D006801:Humans; D007261:Infusions, Intra-Arterial; D007432:Intraoperative Period; D009203:Myocardial Infarction / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D011184:Postoperative Period; D011300:Preoperative Care; D013300:Streptokinase / Q000008:administration & dosage
D013300:Streptokinase