title: Hereford cattle immunized and protected against Boophilus microplus with soluble and membrane-associated antigens from the midgut of ticks.
abstract: Hereford cattle were immunized with membranes and soluble components extracted from the midgut of Boophilus microplus. Membrane vaccines protected cattle (91%) against challenge with 3 x 20,000 larval ticks administered at intervals of 7 days. Vaccines made from soluble antigens did not protect cattle. Antibody levels measured by enzyme-linked immunosorbent assay (ELISA) related to the levels of protection induced by vaccination.
authors.affiliation: Department of Parasitology, University of Queensland, St Lucia, Brisbane, Australia.
authors.forename: J P
authors.initials: JP
authors.lastname: Opdebeeck
authors.forename: J Y
authors.initials: JY
authors.lastname: Wong
authors.forename: L A
authors.initials: LA
authors.lastname: Jackson
authors.forename: C
authors.initials: C
authors.lastname: Dobson
mesh_terms: D000818:Animals; D000917:Antibody Formation; D000941:Antigens / Q000276:immunology*; D002417:Cattle; D002418:Cattle Diseases / Q000517:prevention & control*; D008297:Male; D013984:Tick Infestations / Q000517:prevention & control / Q000662:veterinary*; D013987:Ticks / Q000276:immunology*; D014611:Vaccination / Q000662:veterinary*
chemical_list: D000941:Antigens