title: [Influence of dietary protein levels on the electrophoretic pattern and plasma IgG and IgM levels in pregnant rats and their offspring].
abstract: In view of the influence that nutritional and physiological status exert on the immunological capacity of the subject, a study was carried out for the purpose of studying the changes induced by three protein levels in the diet: (4%, 10% (control), and 20%) on total plasma proteins (TPP) and their fractions, as well as Ig G and Ig M levels in non-pregnant (NP) and pregnant (P) rats and their offspring. Effect of the diet on adult rats--In non-pregnant rats submitted to the high protein diet, Ig G levels increased while TPP decreased in P rats fed on 4% and 20% protein diets. The higher the protein level in the diet, the higher were the TPP values. Effect of pregnancy--Ig G and Ig M levels suffered an increase in rats fed the 4% and 10% protein diets, while a decrease was observed in rats submitted to the 20% protein level diet. The TPP rate diminished in rats fed on the low protein diets, and increased when the highest protein diet was administered. Effect of the diet on offspring--Ig M levels were only detected in neonates from rats fed with the low and high protein diets. Moreover, the TPP rate increased as a direct function of the dietary protein intake.
authors.affiliation: Universidad Complutense, Madrid, España.
authors.forename: P
authors.initials: P
authors.lastname: Varela
authors.forename: E
authors.initials: E
authors.lastname: Muñoz-Martínez
authors.forename: A
authors.initials: A
authors.lastname: Marcos
authors.forename: M T
authors.initials: MT
authors.lastname: Unzaga
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology; D001797:Blood Protein Electrophoresis; D004032:Diet; D004044:Dietary Proteins / Q000008:administration & dosage* / Q000494:pharmacology; D005260:Female; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D004044:Dietary Proteins; D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: Influencia del nivel proteínico dietario sobre el patrón electroforético y los niveles de Ig G e Ig M plasmáticos en ratas gestantes y sus neonatos.