The 20 alpha-hydroxysteroid dehydrogenase of Streptomyces hydrogenans.
In addition to the well-known 3 alpha,20 beta-hydroxysteroid dehydrogenase ('cortisone reductase'), Streptomyces hydrogenans produces a relatively stable, NAD-dependent 20 alpha-hydroxysteroid dehydrogenase of molecular mass approximately 48 kDa. This enzyme catalyzes the transfer of hydrogen from the 4-pro-S position of NADH.
Rimsay
R L
RL
Faculty of Medicine, Health Sciences Centre, Memorial University of Newfoundland, St. John's, Canada.
Murphy
G W
GW
Martin
C J
CJ
Orr
J C
JC
D015089:20-Hydroxysteroid Dehydrogenases / Q000302:isolation & purification*; D043607:20-alpha-Hydroxysteroid Dehydrogenase; D002384:Catalysis; D004591:Electrophoresis, Polyacrylamide Gel; D006859:Hydrogen / Q000378:metabolism; D008970:Molecular Weight; D009243:NAD / Q000378:metabolism; D013302:Streptomyces / Q000201:enzymology*
D009243:NAD; D006859:Hydrogen; D015089:20-Hydroxysteroid Dehydrogenases; D043607:20-alpha-Hydroxysteroid Dehydrogenase