Xanthine oxidase activity in intestinal tumors induced by 1,2-dimethylhydrazine dihydrochloride.
1,2-Dimethylhydrazine-induced large bowel tumors in adult male rats contained significantly lower levels of xanthine oxidase and xanthine dehydrogenase activities when compared to levels in normal intestinal tissue. Xanthine dehydrogenase activity in the blood serum of DMH-treated rats was significantly higher than that of the control animals.
Mitidieri
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Centro de Pesquisa Básica, Instituto National de Câncer, Rio de Janeiro, Brasil.
Souza
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AS
Affonso
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D000818:Animals; D003110:Colonic Neoplasms / Q000139:chemically induced* / Q000201:enzymology; D004127:Dimethylhydrazines; D008297:Male; D051381:Rats; D014968:Xanthine Dehydrogenase / Q000097:blood / Q000378:metabolism; D014969:Xanthine Oxidase / Q000378:metabolism*
D004127:Dimethylhydrazines; D014968:Xanthine Dehydrogenase; D014969:Xanthine Oxidase