title: Solubility and partitioning. IX: Solubility of hydantoins in water.
abstract: An expression for estimating the aqueous solubility of weak electrolytes under different conditions of temperature and pH has been proposed in a previous publication. The expression, based on the additivity of free energy, separates solubility into three independent contributions. In the present work, the equation is tested with a different set of 18 solutes within the range of temperature of 20 to 50 degrees C and of pH of 1 to 10. The results show that the theoretical relationship between aqueous solubility and the three independent contributions used in the equation is in excellent agreement with the experimental data.
authors.affiliation: College of Pharmacy, University of Arizona, Tucson 85721.
authors.forename: R
authors.initials: R
authors.lastname: Pinal
authors.forename: S H
authors.initials: SH
authors.lastname: Yalkowsky
mesh_terms: D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006827:Hydantoins / Q000032:analysis*; D006863:Hydrogen-Ion Concentration; D012995:Solubility; D013816:Thermodynamics
chemical_list: D006827:Hydantoins