title: Red cell enzyme polymorphisms in Papua New Guinea Eastern Highlands.
abstract: Ten red cell enzyme polymorphisms, malic dehydrogenase (MDH1), adenylate kinase (AK), phosphohexose isomerase (PHI), adenosine deaminase (ADA), esterase D (ESD), glutamic pyruvic transaminase (GPT), acid phosphatase (ACP1), phosphoglucomutase 1 and 2 (PGM1, PGM2), phosphogluconate dehydrogenase (PGD) were investigated in the Baruya tribe and several Anga tribes living high in the Wonenara and Marawaka valleys in Papua New Guinea Eastern Highlands (6.5S, 145.5E). Also a non-Anga tribe, the Aziana or Kenaze, was sampled. Variants were observed in ADA, PGM1 and PGM2. AK and PHI were monomorphic, all subjects being AK 1 and PHI 1; MDH1 was also monomorphic in Anga while variants were observed in Aziana. This latter tribe differed markedly in each system from the Anga peoples.
authors.affiliation: Institut National de Transfusion Sanguine, Etablissement Saint Antoine, Paris, France.
authors.forename: J
authors.initials: J
authors.lastname: Seger
authors.forename: M
authors.initials: M
authors.lastname: Godelier
authors.forename: L
authors.initials: L
authors.lastname: Halle
authors.forename: P
authors.initials: P
authors.lastname: Lemonnier
authors.forename: J L
authors.initials: JL
authors.lastname: Lory
authors.forename: P
authors.initials: P
authors.lastname: Rouger
authors.forename: J
authors.initials: J
authors.lastname: Ruffie
authors.forename: D
authors.initials: D
authors.lastname: Salmon
mesh_terms: D000483:Alleles; D044383:Black People / Q000235:genetics; D004912:Erythrocytes / Q000201:enzymology*; D005787:Gene Frequency; D006801:Humans; D007527:Isoenzymes / Q000097:blood / Q000235:genetics*; D010219:Papua New Guinea; D010641:Phenotype; D011110:Polymorphism, Genetic
chemical_list: D007527:Isoenzymes