title: Age-related reference values for free amino acids in first morning urine specimens.
abstract: We determined age-related reference values for urinary free amino acids (in mmol/mol creatinine) in first morning urine specimens from 360 control subjects who were divided into nine age groups: birth to 1 month, 1-6 months, 6-12 months, 1-2 years, 2-4 years, 4-7 years, 7-10 years, 10-13 years, and older than 13 years. Except for taurine and 3-methylhistidine, the concentration of all the amino acids decreased with increasing age. The use of these results to detect aminoacidopathies and tubulopathies is discussed.
authors.affiliation: Laboratoire de Biochimie Médicale B, Hôpital Necker-Enfants Malades, Paris, France.
authors.forename: P R
authors.initials: PR
authors.lastname: Parvy
authors.forename: J I
authors.initials: JI
authors.lastname: Bardet
authors.forename: D M
authors.initials: DM
authors.lastname: Rabier
authors.forename: P P
authors.initials: PP
authors.lastname: Kamoun
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000596:Amino Acids / Q000652:urine*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008762:Methylhistidines / Q000652:urine; D012016:Reference Values; D013654:Taurine / Q000652:urine
chemical_list: D000596:Amino Acids; D008762:Methylhistidines; D013654:Taurine; C028118:3-methylhistidine