title: Legal and scientific probability of causation of cancer and other environmental disease in individuals.
abstract: How to evaluate and apply probabilistic scientific evidence that cancer (or other diseases) have been caused by chemical substances (or other environmental agents) constitutes a critical problem which must be addressed by legal institutions. This article analyzes the basis of the current scientific concepts of causation and the means of incorporating epidemiological and statistical evidence of causation into the legal process, primarily with respect to cases of harm to individuals. Experiments with and adjustments of the legal system to effect an adequate accommodation of such probabilistic evidence are suggested.
authors.forename: T A
authors.initials: TA
authors.lastname: Brennan
authors.forename: R F
authors.initials: RF
authors.lastname: Carter
mesh_terms: D001681:Biological Assay; D004305:Dose-Response Relationship, Drug; D004812:Epidemiologic Methods; D006801:Humans; D007883:Legislation, Medical; D009152:Mutagenicity Tests; D009369:Neoplasms / Q000139:chemically induced / Q000209:etiology*; D010686:Philosophy, Medical; D014481:United States; D026712:Value of Life; D014942:Workers' Compensation