The effect of ipratropium bromide (Atrovent) on the air conditioning capacity of the nose.
The air conditioning capacity of the nose was assessed by a method which permits measurements in both nasal cavities without blockage of the passage between the nasopharynx and oropharynx. By this method the degree of warming of the air and its humidification during the passage through the nasal cavity can be calculated. The effect of intranasal application of ipratropium bromide (Atrovent) on the air conditioning capacity of the nasal mucosa was evaluated in a group of normal subjects and a group of patients with vasomotor rhinitis. In this short term trial Atrovent was found not to have any effect on this capacity.
Kumlien
J
J
Drettner
B
B
D000328:Adult; D000368:Aged; D001286:Atropine Derivatives / Q000494:pharmacology*; D005260:Female; D006801:Humans; D009241:Ipratropium / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000187:drug effects* / Q000378:metabolism; D009666:Nose / Q000502:physiology*; D012119:Respiration; D012223:Rhinitis, Vasomotor / Q000503:physiopathology
D001286:Atropine Derivatives; D009241:Ipratropium