title: The effects of cerebral hemidecortication on the eruption rate and uptake of [3H]-glycine by the periodontal ligament of the rat incisor.
abstract: Hemidecortication, which consists of removing one cerebral hemisphere, leaving intact the thalamus and hypothalamus, affects the hypothalamus-hypophyseal axis producing hypothyroidism. Hemidecorticate rats showed a significant decrease in the weekly eruption rate of the upper incisors and partial recovery after the administration of thyrotrophin-releasing hormone (TRH). The uptake of [3H]-glycine, 1 and 4 h after a single injection, shown by radioautography, was 25 to 50 per cent higher in the periodontal ligament of the experimental animals. Most of the labelled material was non-collagenous proteins because only 20 to 30 per cent was removed by collagenase.
authors.affiliation: Department of Morphology, School of Dentistry, UNICAMP, Piracicaba, SP, Brazil.
authors.forename: M do C
authors.initials: Mdo C
authors.lastname: Tse
authors.forename: M C
authors.initials: MC
authors.lastname: Boaventura
authors.forename: G D
authors.initials: GD
authors.lastname: Fernandes
authors.forename: J
authors.initials: J
authors.lastname: Merzel
mesh_terms: D000818:Animals; D002540:Cerebral Cortex / Q000502:physiology; D005998:Glycine / Q000378:metabolism*; D007180:Incisor; D008297:Male; D010513:Periodontal Ligament / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013963:Thyroid Hormones / Q000502:physiology*; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology; D014078:Tooth Eruption / Q000187:drug effects
chemical_list: D013963:Thyroid Hormones; D013973:Thyrotropin-Releasing Hormone; D005998:Glycine