title: [Interaction of prostaglandins with low-density lipoproteins in human blood].
abstract: Interaction of prostaglandins (PG) with human plasma low density lipoproteins (LDL) was studied, using fluorescent spectroscopy and photoreactive labeling. It was demonstrated that PGE1 at low concentrations (less than 10(-9) M) induces specific lipid rearrangements on the surface of LDL globules. It was assumed that these rearrangements are brought about by the interaction of PG with apolipoprotein B to form short-living complexes. A possible mechanism and biological significance of the observed phenomenon are discussed.
authors.forename: M A
authors.initials: MA
authors.lastname: Martynova
authors.forename: E M
authors.initials: EM
authors.lastname: Manevich
authors.forename: E L
authors.initials: EL
authors.lastname: Vodovozova
authors.forename: G I
authors.initials: GI
authors.lastname: Muzia
authors.forename: V V
authors.initials: VV
authors.lastname: Bezuglov
mesh_terms: D000527:Alprostadil / Q000097:blood; D001055:Apolipoproteins B / Q000097:blood; D015232:Dinoprostone / Q000097:blood; D005456:Fluorescent Dyes; D006801:Humans; D008077:Lipoproteins, LDL / Q000097:blood*; D011453:Prostaglandins / Q000097:blood*; D011460:Prostaglandins F / Q000097:blood; D013050:Spectrometry, Fluorescence
chemical_list: D001055:Apolipoproteins B; D005456:Fluorescent Dyes; D008077:Lipoproteins, LDL; D011453:Prostaglandins; D011460:Prostaglandins F; D000527:Alprostadil; D015232:Dinoprostone; C100006:prostaglandin F1
vernacular_title: Vzaimodeĭstvie prostaglandinov s lipoproteinami nizkoĭ plotnosti krovi cheloveka.