title: [Reye-like syndrome following valproate therapy in an adult].
abstract: Three months after anticonvulsive regulation by means of the spasmolytic agent Convulsofin, a 46-year-old man suffered severe hepatosis, and when the preparation was discontinued he suffered a severe cerebral dysfunction. The clinical picture is interpreted as being "similar to the Reye syndrome", and distinctions between this and previously reported cases are noted. There has been very little observation of such complications among adult patients.
authors.affiliation: Neurologische Klinik, Bezirksnervenklinik Brandenburg.
authors.forename: M
authors.initials: M
authors.lastname: Klein
authors.forename: U
authors.initials: U
authors.lastname: Wendt
mesh_terms: D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology; D004359:Drug Therapy, Combination; D004828:Epilepsies, Partial / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012202:Reye Syndrome / Q000139:chemically induced*; D014635:Valproic Acid / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D014635:Valproic Acid
vernacular_title: Reye-ähnliches Syndrom nach Valproinat-Therapie bei einem Erwachsenen.