Factors influencing the transfusion effect.
Pretransplant blood transfusions can improve kidney graft survival, but they risk sensitizing the patient. One transfusion induces the beneficial transfusion effect and has a minimal risk for sensitization. Recipients with different HLA-DR phenotypes may need different numbers of transfusions to improve graft survival. For nontransfused recipients it is important to receive a well-matched HLA-DR kidney.
Lagaaij
E L
EL
Eurotransplant Foundation, University Hospital-Leiden, The Netherlands.
Persijn
G G
GG
D001803:Blood Transfusion; D006085:Graft Survival; D006680:HLA Antigens; D006801:Humans; D016030:Kidney Transplantation / Q000276:immunology*
D006680:HLA Antigens