Management of acute severe verapamil intoxication.
A 41-year-old man ingested 6.8 g of verapamil in a suicide attempt. The patient was severely hypotensive, oliguric, and developed a variety of dysrhythmias. He was also hyperglycemic. The patient was successfully resuscitated with intravenous normal saline, calcium chloride, dopamine, and norepinephrine. A review of the manifestations of verapamil intoxication and suggestions for management are outlined.
McMillan
R
R
Department of Medicine, McMaster University Medical Centre, Ontario, Canada.
D000208:Acute Disease; D000328:Adult; D002122:Calcium Chloride / Q000627:therapeutic use; D002302:Cardiac Output / Q000187:drug effects*; D002395:Catecholamines / Q000627:therapeutic use*; D006327:Heart Block / Q000139:chemically induced*; D006801:Humans; D006943:Hyperglycemia / Q000139:chemically induced; D007022:Hypotension / Q000139:chemically induced*; D008297:Male; D013406:Suicide, Attempted; D014700:Verapamil / Q000506:poisoning*
D002395:Catecholamines; D014700:Verapamil; D002122:Calcium Chloride