title: Therapeutic studies on vulvar vestibulitis.
abstract: Established drugs that could logically be hoped to have a beneficial effect on vulvar vestibulitis were evaluated empirically in small, uncontrolled, pilot studies. A small number of spontaneous remissions occurred in the groups using oral isotretinoin or progesterone cream. Apparent therapeutic responses were observed in women using oral dapsone, oral acyclovir or topical capsaicin. A further investigation of the last two drugs is warranted.
authors.affiliation: Department of Obstetrics and Gynecology, University of Florida College of Medicine, Gainesville 32610.
authors.forename: E G
authors.initials: EG
authors.lastname: Friedrich
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D002211:Capsaicin / Q000627:therapeutic use; D003622:Dapsone / Q000627:therapeutic use; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D015474:Isotretinoin; D011374:Progesterone / Q000627:therapeutic use; D014212:Tretinoin / Q000627:therapeutic use; D014847:Vulvitis / Q000188:drug therapy*
chemical_list: D011374:Progesterone; D014212:Tretinoin; D003622:Dapsone; D015474:Isotretinoin; D002211:Capsaicin; D000212:Acyclovir