Structural gene encoding human factor XII is located at 5q33-qter.
The gene encoding human factor XII (F12) or Hageman factor has been mapped to 5q33-qter. This has been achieved by analyzing the results obtained from hybridizing a cloned fragment from the factor XII gene to a panel of human-hamster somatic cell hybrid DNAs and also by in situ hybridization to normal human metaphase cells. The previously reported results localizing F12 to 6p23 are discussed.
Royle
N J
NJ
Department of Human Genetics, University of Manitoba, Canada.
Nigli
M
M
Cool
D
D
MacGillivray
R T
RT
Hamerton
J L
JL
D000818:Animals; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002895:Chromosomes, Human, Pair 5; D006224:Cricetinae; D005174:Factor XII / Q000235:genetics*; D005796:Genes; D006801:Humans; D006822:Hybrid Cells; D007621:Karyotyping; D012689:Sequence Homology, Nucleic Acid
D005174:Factor XII