Coagulation, inflammation, and responses to injury.
Several mechanisms contributing to the development of post-traumatic alterations in organ function are reviewed. The importance of interactions between clotting and inflammatory mediators is detailed. A discussion of management strategies emphasizes the role of early recognition and aggressive treatment of organ dysfunction.
Pottmeyer
E
E
Department of Surgery, University of California, Davis.
Vassar
M J
MJ
Holcroft
J W
JW
D000210:Acute-Phase Reaction / Q000503:physiopathology*; D001095:Arachidonic Acids / Q000378:metabolism; D001777:Blood Coagulation; D003167:Complement Activation; D006728:Hormones / Q000502:physiology; D006801:Humans; D007249:Inflammation / Q000503:physiopathology*; D013564:Sympathetic Nervous System / Q000502:physiology; D014661:Vasoconstriction; D014947:Wounds and Injuries / Q000503:physiopathology*
D001095:Arachidonic Acids; D006728:Hormones