Simultaneous dual isotope studies in the diagnosis of infection.
A simultaneous dual isotope technique incorporating computer subtraction for the diagnosis of bone, joint, or soft-tissue infection using [67Ga]citrate and [99mTc]MDP or sulfur colloid is described. Comparison of this technique with visual congruence or noncongruence of the two radionuclide images in 41 patients shows that the two techniques have identical sensitivity (93%) and specificity (92%) but the computer technique gave additional information in 17% of all cases (44% of abnormals) concerning the anatomic location of the infective focus which aided in the subsequent surgical management of the patient.
Malik
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D000293:Adolescent; D000328:Adult; D000368:Aged; D001847:Bone Diseases / Q000000981:diagnostic imaging*; D002648:Child; D002675:Child, Preschool; D003201:Computers; D003240:Connective Tissue Diseases / Q000000981:diagnostic imaging*; D004164:Diphosphonates; D005260:Female; D005710:Gallium Radioisotopes; D006801:Humans; D007239:Infections / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013382:Subtraction Technique; D013667:Technetium; D013669:Technetium Tc 99m Medronate; D013671:Technetium Tc 99m Sulfur Colloid
D004164:Diphosphonates; D005710:Gallium Radioisotopes; D013671:Technetium Tc 99m Sulfur Colloid; D013667:Technetium; D013669:Technetium Tc 99m Medronate