title: Lactate dehydrogenase isoenzyme-1 in the mediastinal yolk sac tumor.
abstract: LDH isozymes in both the serum and tumor tissues of 4 patients with mediastinal yolk sac tumors, and in the cystic content of tumors transplanted into nude mice was examined. Our findings suggested that LDH-1, along with AFP, is an important marker of this tumor, and that LDH isozyme study is necessary for its diagnosis.
authors.affiliation: Department of Thoracic Surgery, Kyoto University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Ito
authors.forename: T
authors.initials: T
authors.lastname: Taki
authors.forename: A
authors.initials: A
authors.lastname: Mitsuoka
authors.forename: M
authors.initials: M
authors.lastname: Miyake
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D014408:Biomarkers, Tumor / Q000032:analysis*; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000032:analysis* / Q000096:biosynthesis; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis* / Q000201:enzymology / Q000601:surgery; D008649:Mesonephroma / Q000175:diagnosis* / Q000201:enzymology / Q000601:surgery; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation
chemical_list: D014408:Biomarkers, Tumor; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase